Sample records for lawrencium 256

  1. Measurement of the first ionization potential of lawrencium, element 103.

    PubMed

    Sato, T K; Asai, M; Borschevsky, A; Stora, T; Sato, N; Kaneya, Y; Tsukada, K; Düllmann, Ch E; Eberhardt, K; Eliav, E; Ichikawa, S; Kaldor, U; Kratz, J V; Miyashita, S; Nagame, Y; Ooe, K; Osa, A; Renisch, D; Runke, J; Schädel, M; Thörle-Pospiech, P; Toyoshima, A; Trautmann, N

    2015-04-09

    The chemical properties of an element are primarily governed by the configuration of electrons in the valence shell. Relativistic effects influence the electronic structure of heavy elements in the sixth row of the periodic table, and these effects increase dramatically in the seventh row--including the actinides--even affecting ground-state configurations. Atomic s and p1/2 orbitals are stabilized by relativistic effects, whereas p3/2, d and f orbitals are destabilized, so that ground-state configurations of heavy elements may differ from those of lighter elements in the same group. The first ionization potential (IP1) is a measure of the energy required to remove one valence electron from a neutral atom, and is an atomic property that reflects the outermost electronic configuration. Precise and accurate experimental determination of IP1 gives information on the binding energy of valence electrons, and also, therefore, on the degree of relativistic stabilization. However, such measurements are hampered by the difficulty in obtaining the heaviest elements on scales of more than one atom at a time. Here we report that the experimentally obtained IP1 of the heaviest actinide, lawrencium (Lr, atomic number 103), is 4.96(+0.08)(-0.07) electronvolts. The IP1 of Lr was measured with (256)Lr (half-life 27 seconds) using an efficient surface ion-source and a radioisotope detection system coupled to a mass separator. The measured IP1 is in excellent agreement with the value of 4.963(15) electronvolts predicted here by state-of-the-art relativistic calculations. The present work provides a reliable benchmark for theoretical calculations and also opens the way for IP1 measurements of superheavy elements (that is, transactinides) on an atom-at-a-time scale.

  2. 40 CFR 256.40 - Requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Requirements. 256.40 Section 256.40 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Facility Planning and Implementation § 256.40...

  3. 40 CFR 256.40 - Requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirements. 256.40 Section 256.40 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Facility Planning and Implementation § 256.40...

  4. 40 CFR 256.40 - Requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Requirements. 256.40 Section 256.40 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Facility Planning and Implementation § 256.40...

  5. 40 CFR 256.40 - Requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirements. 256.40 Section 256.40 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Facility Planning and Implementation § 256.40...

  6. 40 CFR 256.40 - Requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirements. 256.40 Section 256.40 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Facility Planning and Implementation § 256.40...

  7. 40 CFR 256.11 - Recommendations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommendations. 256.11 Section 256.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT...; Distribution of Funding § 256.11 Recommendations. (a) Responsibilities should be identified for each of the...

  8. 40 CFR 256.11 - Recommendations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommendations. 256.11 Section 256.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT...; Distribution of Funding § 256.11 Recommendations. (a) Responsibilities should be identified for each of the...

  9. 30 CFR 256.2 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Policy. 256.2 Section 256.2 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas, and Sulphur Management, General § 256.2 Policy...

  10. 17 CFR 38.256 - Trade reconstruction.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 1 2014-04-01 2014-04-01 false Trade reconstruction. 38.256 Section 38.256 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION DESIGNATED CONTRACT MARKETS Prevention of Market Disruption § 38.256 Trade reconstruction. The designated contract market must...

  11. 17 CFR 38.256 - Trade reconstruction.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Trade reconstruction. 38.256 Section 38.256 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION DESIGNATED CONTRACT MARKETS Prevention of Market Disruption § 38.256 Trade reconstruction. The designated contract market must...

  12. 25 CFR 256.4 - Information Collection.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Information Collection. 256.4 Section 256.4 Indians... Information Collection. The information collection requirements contained in § 256.9 have been approved by the... information is collected to determine applicant eligibility for services and eligibility to participate in the...

  13. 30 CFR 256.71 - Directional drilling.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Directional drilling. 256.71 Section 256.71..., and Extensions § 256.71 Directional drilling. In accordance with an approved exploration plan or development and production plan, a lease may be maintained in force by directional wells drilled under the...

  14. 40 CFR 25.6 - Public meetings.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Public meetings. 25.6 Section 25.6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PUBLIC PARTICIPATION IN PROGRAMS UNDER THE RESOURCE CONSERVATION AND RECOVERY ACT, THE SAFE DRINKING WATER ACT, AND THE CLEAN WATER ACT § 25.6 Public...

  15. 30 CFR 256.71 - Directional drilling.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Directional drilling. 256.71 Section 256.71... OIL AND GAS IN THE OUTER CONTINENTAL SHELF Assignments, Transfers, and Extensions § 256.71 Directional drilling. In accordance with an approved exploration plan or development and production plan, a lease may...

  16. 30 CFR 256.71 - Directional drilling.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Directional drilling. 256.71 Section 256.71... LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Assignments, Transfers, and Extensions § 256.71 Directional drilling. In accordance with a BOEM-approved exploration plan or development and...

  17. 30 CFR 256.71 - Directional drilling.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Directional drilling. 256.71 Section 256.71... LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Assignments, Transfers, and Extensions § 256.71 Directional drilling. In accordance with a BOEM-approved exploration plan or development and...

  18. 30 CFR 256.71 - Directional drilling.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Directional drilling. 256.71 Section 256.71... LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Assignments, Transfers, and Extensions § 256.71 Directional drilling. In accordance with a BOEM-approved exploration plan or development and...

  19. 30 CFR 256.82 - Environmental studies.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Environmental studies. 256.82 Section 256.82... INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Studies § 256.82 Environmental studies. (a) The Director shall conduct a study of any area or region included in any lease sale...

  20. 30 CFR 256.82 - Environmental studies.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Environmental studies. 256.82 Section 256.82... OIL AND GAS IN THE OUTER CONTINENTAL SHELF Studies § 256.82 Environmental studies. (a) The Director shall conduct a study of any area or region included in any lease sale in order to establish information...

  1. 30 CFR 256.63 - Service fees.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Service fees. 256.63 Section 256.63 Mineral... IN THE OUTER CONTINENTAL SHELF Assignments, Transfers, and Extensions § 256.63 Service fees. (a) The table in this paragraph (a) shows the fees that you must pay to MMS for the services listed. The fees...

  2. 17 CFR 256.01-7 - Records.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Records. 256.01-7 Section 256... COMPANY ACT OF 1935 General Instructions § 256.01-7 Records. (a) The books of account and other records of... identification and audit. (b) The books and records referred to herein shall include not only accounting records...

  3. 17 CFR 256.01-7 - Records.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Records. 256.01-7 Section 256... COMPANY ACT OF 1935 General Instructions § 256.01-7 Records. (a) The books of account and other records of... identification and audit. (b) The books and records referred to herein shall include not only accounting records...

  4. 17 CFR 256.931 - Rents.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Rents. 256.931 Section 256.931 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) UNIFORM SYSTEM OF ACCOUNTS..., computers, data processing equipment, micro-wave and telecommunication equipment, airplanes, automobiles...

  5. 17 CFR 256.301 - Organization.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Organization. 256.301 Section 256.301 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) UNIFORM... service company such as stock, minute books and corporate seal. Note: This account shall not include any...

  6. 17 CFR 256.301 - Organization.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Organization. 256.301 Section 256.301 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) UNIFORM... service company such as stock, minute books and corporate seal. Note: This account shall not include any...

  7. 30 CFR 256.26 - General.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false General. 256.26 Section 256.26 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS... for environmental analysis and consideration for leasing. The Director, on his/her own motion, may...

  8. 7 CFR 2018.256-2018.300 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false [Reserved] 2018.256-2018.300 Section 2018.256-2018.300 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL... (CONTINUED) ADMINISTRATIVE REGULATIONS GENERAL Availability of Information §§ 2018.256-2018.300 [Reserved] ...

  9. 7 CFR 2018.256-2018.300 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 15 2011-01-01 2011-01-01 false [Reserved] 2018.256-2018.300 Section 2018.256-2018.300 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL... (CONTINUED) ADMINISTRATIVE REGULATIONS GENERAL Availability of Information §§ 2018.256-2018.300 [Reserved] ...

  10. 7 CFR 2018.256-2018.300 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 15 2014-01-01 2014-01-01 false [Reserved] 2018.256-2018.300 Section 2018.256-2018.300 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL... (CONTINUED) ADMINISTRATIVE REGULATIONS GENERAL Availability of Information §§ 2018.256-2018.300 [Reserved] ...

  11. 7 CFR 2018.256-2018.300 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false [Reserved] 2018.256-2018.300 Section 2018.256-2018.300 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL... (CONTINUED) ADMINISTRATIVE REGULATIONS GENERAL Availability of Information §§ 2018.256-2018.300 [Reserved] ...

  12. 7 CFR 2018.256-2018.300 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false [Reserved] 2018.256-2018.300 Section 2018.256-2018.300 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL... (CONTINUED) ADMINISTRATIVE REGULATIONS GENERAL Availability of Information §§ 2018.256-2018.300 [Reserved] ...

  13. 30 CFR 256.2 - Policy.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Policy. 256.2 Section 256.2 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas, and...

  14. 27 CFR 24.256 - Bottle aging wine.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Bottle aging wine. 24.256 Section 24.256 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT... of Wine § 24.256 Bottle aging wine. Wine bottled or packed and stored for the purpose of aging need...

  15. 27 CFR 24.256 - Bottle aging wine.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Bottle aging wine. 24.256 Section 24.256 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT... of Wine § 24.256 Bottle aging wine. Wine bottled or packed and stored for the purpose of aging need...

  16. 27 CFR 24.256 - Bottle aging wine.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Bottle aging wine. 24.256 Section 24.256 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT... of Wine § 24.256 Bottle aging wine. Wine bottled or packed and stored for the purpose of aging need...

  17. 27 CFR 24.256 - Bottle aging wine.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Bottle aging wine. 24.256 Section 24.256 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT... of Wine § 24.256 Bottle aging wine. Wine bottled or packed and stored for the purpose of aging need...

  18. 42 CFR 84.256 - Quality control requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Quality control requirements. 84.256 Section 84.256... § 84.256 Quality control requirements. (a) In addition to the construction and performance requirements specified in §§ 84.251, 84.252, 84.253, 84.254, and 84.255, the quality control requirements in paragraphs...

  19. 42 CFR 84.256 - Quality control requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Quality control requirements. 84.256 Section 84.256... § 84.256 Quality control requirements. (a) In addition to the construction and performance requirements specified in §§ 84.251, 84.252, 84.253, 84.254, and 84.255, the quality control requirements in paragraphs...

  20. 42 CFR 84.256 - Quality control requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Quality control requirements. 84.256 Section 84.256... § 84.256 Quality control requirements. (a) In addition to the construction and performance requirements specified in §§ 84.251, 84.252, 84.253, 84.254, and 84.255, the quality control requirements in paragraphs...

  1. 42 CFR 84.256 - Quality control requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Quality control requirements. 84.256 Section 84.256... § 84.256 Quality control requirements. (a) In addition to the construction and performance requirements specified in §§ 84.251, 84.252, 84.253, 84.254, and 84.255, the quality control requirements in paragraphs...

  2. 42 CFR 84.256 - Quality control requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Quality control requirements. 84.256 Section 84.256... § 84.256 Quality control requirements. (a) In addition to the construction and performance requirements specified in §§ 84.251, 84.252, 84.253, 84.254, and 84.255, the quality control requirements in paragraphs...

  3. 30 CFR 256.50 - Dating of leases.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Dating of leases. 256.50 Section 256.50 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Issuance of Leases § 256.50 Dating of leases. All leases issued under...

  4. HgCdTe 256x256 NWIR FPA

    NASA Technical Reports Server (NTRS)

    Vural, Kadri; Blessinger, Michael; Chen, Jenkon; Kleinhans, William

    1989-01-01

    Researchers developed a HgCdTe 256x256 focal plane array (FPA) which operates in the 1 to 5 micron band. This is presently the largest demonstrated HgCdTe FPA. The detector material is HgCdTe on sapphire (PACE-1 technology) which has a low thermal expansion mismatch with silicon. The multiplexer is a CMOS FET-switch device processed through a commercial silicon foundry. The multiplexer input is direct injection and the charge capacity is about 2 times 10 to the 7th power electrons. The kTC limited read noise is 400 electrons. Researchers demonstrated high background imaging using the device. The broadband quantum efficiency is measured to be 59 percent. Dark currents less than 0.1 pA were measured at 77 K for detectors processed on PACE-1 material with 4.9 microns cutoff. The dark currents decrease as the temperature is lowered, and researchers are presently studying the T less than 77 K characteristics. The interconnect yield is greater than 95 percent. The devices are available for astronomical applications.

  5. 17 CFR 256.123 - Investment in associate companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Investment in associate companies. 256.123 Section 256.123 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... UTILITY HOLDING COMPANY ACT OF 1935 2. Investments § 256.123 Investment in associate companies. This...

  6. 17 CFR 256.123 - Investment in associate companies.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Investment in associate companies. 256.123 Section 256.123 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... UTILITY HOLDING COMPANY ACT OF 1935 2. Investments § 256.123 Investment in associate companies. This...

  7. 32 CFR 256.7 - Accident potential zone guidelines.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Accident potential zone guidelines. 256.7 Section 256.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS AIR INSTALLATIONS COMPATIBLE USE ZONES § 256.7 Accident potential zone guidelines...

  8. 32 CFR 256.7 - Accident potential zone guidelines.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Accident potential zone guidelines. 256.7 Section 256.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS AIR INSTALLATIONS COMPATIBLE USE ZONES § 256.7 Accident potential zone guidelines...

  9. 17 CFR 256.310 - Aircraft and airport equipment.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Aircraft and airport equipment. 256.310 Section 256.310 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... UTILITY HOLDING COMPANY ACT OF 1935 Service Company Property Accounts § 256.310 Aircraft and airport...

  10. 17 CFR 256.310 - Aircraft and airport equipment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Aircraft and airport equipment. 256.310 Section 256.310 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... UTILITY HOLDING COMPANY ACT OF 1935 Service Company Property Accounts § 256.310 Aircraft and airport...

  11. 17 CFR 256.01-6 - Departmental classification required.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Departmental classification required. 256.01-6 Section 256.01-6 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... UTILITY HOLDING COMPANY ACT OF 1935 General Instructions § 256.01-6 Departmental classification required...

  12. 17 CFR 256.426.1 - Donations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Donations. 256.426.1 Section... COMPANY ACT OF 1935 Income and Expense Accounts § 256.426.1 Donations. This account shall include all payments or donations for charitable, social or community welfare purposes. ...

  13. 17 CFR 256.426.1 - Donations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Donations. 256.426.1 Section... COMPANY ACT OF 1935 Income and Expense Accounts § 256.426.1 Donations. This account shall include all payments or donations for charitable, social or community welfare purposes. ...

  14. 40 CFR 25.6 - Public meetings.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Public meetings. 25.6 Section 25.6... meetings. Public meetings are any assemblies or gathering, (such as conferences, informational sessions... to attend. Public meetings are less formal than public hearings. They do not require formal...

  15. 17 CFR 256.124 - Other investments.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Other investments. 256.124... COMPANY ACT OF 1935 2. Investments § 256.124 Other investments. This account shall include the cost or current value of investments, whichever is less, in securities, club memberships, associations, life...

  16. 17 CFR 256.124 - Other investments.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Other investments. 256.124... COMPANY ACT OF 1935 2. Investments § 256.124 Other investments. This account shall include the cost or current value of investments, whichever is less, in securities, club memberships, associations, life...

  17. 30 CFR 256.12 - Supplemental sales.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Supplemental sales. 256.12 Section 256.12 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas, and Sulphur Management...

  18. 17 CFR 256.01-8 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... SYSTEM OF ACCOUNTS FOR MUTUAL SERVICE COMPANIES AND SUBSIDIARY SERVICE COMPANIES, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 General Instructions § 256.01-8 Definitions. Definitions contained in the Public... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Definitions. 256.01-8 Section...

  19. 17 CFR 256.135 - Working funds.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Working funds. 256.135 Section... COMPANY ACT OF 1935 3. Current and Accrued Assets § 256.135 Working funds. This account shall include cash advanced to officers, agents, employees and others as petty cash or working funds. ...

  20. 17 CFR 256.135 - Working funds.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Working funds. 256.135 Section... COMPANY ACT OF 1935 3. Current and Accrued Assets § 256.135 Working funds. This account shall include cash advanced to officers, agents, employees and others as petty cash or working funds. ...

  1. 17 CFR 256.237 - Interest accrued.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Interest accrued. 256.237... COMPANY ACT OF 1935 7. Current and Accrued Liabilities § 256.237 Interest accrued. This account shall include the amount of interest accrued on all liabilities of the service company. Supporting records shall...

  2. 17 CFR 256.237 - Interest accrued.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Interest accrued. 256.237... COMPANY ACT OF 1935 7. Current and Accrued Liabilities § 256.237 Interest accrued. This account shall include the amount of interest accrued on all liabilities of the service company. Supporting records shall...

  3. 30 CFR 256.80 - Leases of other minerals.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Leases of other minerals. 256.80 Section 256.80 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Section 6 Leases § 256.80 Leases of other minerals. The...

  4. 30 CFR 256.25 - Areas near coastal States.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Areas near coastal States. 256.25 Section 256... SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Call for Information and Nominations § 256.25 Areas near coastal States. (a) At the time information is solicited for leasing of areas within 3...

  5. 17 CFR 256.236 - Taxes accrued.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Taxes accrued. 256.236 Section... COMPANY ACT OF 1935 7. Current and Accrued Liabilities § 256.236 Taxes accrued. (a) This account shall be credited with the amount of taxes accrued during the accounting period, corresponding debits being made to...

  6. 17 CFR 256.409 - Income taxes.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Income taxes. 256.409 Section... COMPANY ACT OF 1935 Income and Expense Accounts § 256.409 Income taxes. (a) This account shall include the amount of local, State and Federal taxes on income properly accruable during the period covered by the...

  7. 17 CFR 256.409 - Income taxes.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Income taxes. 256.409 Section... COMPANY ACT OF 1935 Income and Expense Accounts § 256.409 Income taxes. (a) This account shall include the amount of local, State and Federal taxes on income properly accruable during the period covered by the...

  8. 40 CFR 256.42 - Recommendations for assuring facility development.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommendations for assuring facility development. 256.42 Section 256.42 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID... Planning and Implementation § 256.42 Recommendations for assuring facility development. (a) The State plan...

  9. 17 CFR 256.188 - Research, development, or demonstration expenditures.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Research, development, or demonstration expenditures. 256.188 Section 256.188 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... COMPANIES, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 4. Deferred Debits § 256.188 Research, development, or...

  10. 17 CFR 256.303 - Miscellaneous intangible plant.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Miscellaneous intangible plant. 256.303 Section 256.303 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... plant. (a) This account shall include the cost of patent rights, licenses, privileges, and other...

  11. 17 CFR 256.216 - Unappropriated retained earnings.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... retained earnings. This account shall include the balance, either debit or credit, arising from earnings... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Unappropriated retained earnings. 256.216 Section 256.216 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION...

  12. 24 CFR 203.256 - Insurance of open-end advance.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Insurance of open-end advance. 203.256 Section 203.256 Housing and Urban Development Regulations Relating to Housing and Urban... Insurance § 203.256 Insurance of open-end advance. Insurance on an open-end advance will be evidenced by...

  13. 24 CFR 203.256 - Insurance of open-end advance.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Insurance of open-end advance. 203.256 Section 203.256 Housing and Urban Development Regulations Relating to Housing and Urban... Insurance § 203.256 Insurance of open-end advance. Insurance on an open-end advance will be evidenced by...

  14. 24 CFR 203.256 - Insurance of open-end advance.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Insurance of open-end advance. 203.256 Section 203.256 Housing and Urban Development Regulations Relating to Housing and Urban... Insurance § 203.256 Insurance of open-end advance. Insurance on an open-end advance will be evidenced by...

  15. 24 CFR 203.256 - Insurance of open-end advance.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Insurance of open-end advance. 203.256 Section 203.256 Housing and Urban Development Regulations Relating to Housing and Urban... Insurance § 203.256 Insurance of open-end advance. Insurance on an open-end advance will be evidenced by...

  16. 24 CFR 203.256 - Insurance of open-end advance.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Insurance of open-end advance. 203.256 Section 203.256 Housing and Urban Development Regulations Relating to Housing and Urban... Insurance § 203.256 Insurance of open-end advance. Insurance on an open-end advance will be evidenced by...

  17. 30 CFR 256.10 - Information to States.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Information to States. 256.10 Section 256.10 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas, and Sulphur Management...

  18. 17 CFR 256.920 - Salaries and wages.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Salaries and wages. 256.920... COMPANY ACT OF 1935 2. Expense § 256.920 Salaries and wages. (a) This account shall include salaries, wages, bonuses and other consideration for services, with the exception of director's fees paid directly...

  19. 40 CFR 60.256 - Continuous monitoring requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ....256 Section 60.256 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... rates of 25 Mg (28 tons) per year or more, a bag leak detection system according to the requirements in... performance test on an operating day average basis. (c) Each bag leak detection system used to comply with...

  20. 40 CFR 60.256 - Continuous monitoring requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ....256 Section 60.256 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... rates of 25 Mg (28 tons) per year or more, a bag leak detection system according to the requirements in... performance test on an operating day average basis. (c) Each bag leak detection system used to comply with...

  1. 40 CFR 60.256 - Continuous monitoring requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ....256 Section 60.256 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... rates of 25 Mg (28 tons) per year or more, a bag leak detection system according to the requirements in... performance test on an operating day average basis. (c) Each bag leak detection system used to comply with...

  2. 40 CFR 60.256 - Continuous monitoring requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ....256 Section 60.256 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... rates of 25 Mg (28 tons) per year or more, a bag leak detection system according to the requirements in... performance test on an operating day average basis. (c) Each bag leak detection system used to comply with...

  3. 40 CFR 256.05 - Annual work program.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Annual work program. 256.05 Section..., Definitions § 256.05 Annual work program. (a) The annual work program submitted for financial assistance under... Administrator and the State shall agree on the contents of the annual work program. The Administrator will...

  4. 40 CFR 256.05 - Annual work program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Annual work program. 256.05 Section..., Definitions § 256.05 Annual work program. (a) The annual work program submitted for financial assistance under... Administrator and the State shall agree on the contents of the annual work program. The Administrator will...

  5. 27 CFR 24.256 - Bottle aging wine.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Bottle aging wine. 24.256... OF THE TREASURY LIQUORS WINE Storage, Treatment and Finishing of Wine Bottling, Packing, and Labeling of Wine § 24.256 Bottle aging wine. Wine bottled or packed and stored for the purpose of aging need...

  6. 30 CFR 256.65 - Attorney General review.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Attorney General review. 256.65 Section 256.65... give due consideration to the views of the Attorney General. The Secretary may act on an assignment or transfer if the Attorney General has not responded to the request for consultation within 30 days of said...

  7. 30 CFR 256.43 - Chargeability for production.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....41 of this part, chargeability under § 256.46(g) of this part, 1.454 barrels of natural gas liquids... SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Issuance of Leases § 256.43 Chargeability for..., certificate of deposit for a security, fractional undivided interest in oil, gas, or other mineral rights, or...

  8. 40 CFR 256.25 - Recommendation for inactive facilities.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... notification of agencies responsible for public health and safety. ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Recommendation for inactive facilities. 256.25 Section 256.25 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID...

  9. 40 CFR 256.25 - Recommendation for inactive facilities.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... notification of agencies responsible for public health and safety. ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Recommendation for inactive facilities. 256.25 Section 256.25 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID...

  10. 40 CFR 256.25 - Recommendation for inactive facilities.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... notification of agencies responsible for public health and safety. ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Recommendation for inactive facilities. 256.25 Section 256.25 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID...

  11. 40 CFR 256.65 - Recommendations for public participation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... participation. 256.65 Section 256.65 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Public... designed to encourage informed public participation in the development and implementation of solid waste...

  12. 40 CFR 256.25 - Recommendation for inactive facilities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommendation for inactive facilities. 256.25 Section 256.25 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste...

  13. 40 CFR 256.25 - Recommendation for inactive facilities.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommendation for inactive facilities. 256.25 Section 256.25 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste...

  14. 24 CFR 25.6 - Violations creating grounds for administrative action.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Violations creating grounds for administrative action. 25.6 Section 25.6 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development MORTGAGEE REVIEW BOARD § 25.6 Violations creating grounds for administrative...

  15. 25 CFR 256.12 - Who administers the Housing Improvement Program?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Who administers the Housing Improvement Program? 256.12 Section 256.12 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HOUSING HOUSING IMPROVEMENT PROGRAM § 256.12 Who administers the Housing Improvement Program? The Housing Improvement Program is...

  16. 25 CFR 256.12 - Who administers the Housing Improvement Program?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Who administers the Housing Improvement Program? 256.12 Section 256.12 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HOUSING HOUSING IMPROVEMENT PROGRAM § 256.12 Who administers the Housing Improvement Program? The Housing Improvement Program is...

  17. 25 CFR 256.12 - Who administers the Housing Improvement Program?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Who administers the Housing Improvement Program? 256.12 Section 256.12 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HOUSING HOUSING IMPROVEMENT PROGRAM § 256.12 Who administers the Housing Improvement Program? The Housing Improvement Program is...

  18. 25 CFR 256.12 - Who administers the Housing Improvement Program?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Who administers the Housing Improvement Program? 256.12 Section 256.12 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HOUSING HOUSING IMPROVEMENT PROGRAM § 256.12 Who administers the Housing Improvement Program? The Housing Improvement Program is...

  19. 25 CFR 256.12 - Who administers the Housing Improvement Program?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Who administers the Housing Improvement Program? 256.12 Section 256.12 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HOUSING HOUSING IMPROVEMENT PROGRAM § 256.12 Who administers the Housing Improvement Program? The Housing Improvement Program is...

  20. 7 CFR 1220.256 - Separability.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOYBEAN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Soybean Promotion and Research Order Miscellaneous § 1220.256 Separability. If any...

  1. 7 CFR 1220.256 - Separability.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOYBEAN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Soybean Promotion and Research Order Miscellaneous § 1220.256 Separability. If any...

  2. 15 CFR 256.2 - The Research Associate Program.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false The Research Associate Program. 256.2... INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE FELLOWSHIPS AND RESEARCH ASSOCIATES RESEARCH ASSOCIATE PROGRAM § 256.2 The Research Associate Program. The Bureau provides its facilities, scientific...

  3. 15 CFR 256.2 - The Research Associate Program.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false The Research Associate Program. 256.2... INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE FELLOWSHIPS AND RESEARCH ASSOCIATES RESEARCH ASSOCIATE PROGRAM § 256.2 The Research Associate Program. The Bureau provides its facilities, scientific...

  4. 15 CFR 256.2 - The Research Associate Program.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false The Research Associate Program. 256.2... INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE FELLOWSHIPS AND RESEARCH ASSOCIATES RESEARCH ASSOCIATE PROGRAM § 256.2 The Research Associate Program. The Bureau provides its facilities, scientific...

  5. 17 CFR 256.01-13 - Submission of questions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Submission of questions. 256.01-13 Section 256.01-13 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... interpretation of the prescribed accounting to the Division of Corporate Regulation or its successor for...

  6. 30 CFR 256.29 - Proposed notice of sale.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Proposed notice of sale. 256.29 Section 256.29 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE... measures, including lease stipulations and conditions, to mitigate adverse impacts on the environments. For...

  7. 30 CFR 256.8 - Leasing maps and diagrams.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Leasing maps and diagrams. 256.8 Section 256.8 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas, and Sulphur Management...

  8. 17 CFR 256.411.5 - Investment tax credit.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Investment tax credit. 256.411... HOLDING COMPANY ACT OF 1935 Income and Expense Accounts § 256.411.5 Investment tax credit. (a) This account shall be debited with the amounts of investment tax credits related to service company property...

  9. 17 CFR 256.411.5 - Investment tax credit.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Investment tax credit. 256.411... HOLDING COMPANY ACT OF 1935 Income and Expense Accounts § 256.411.5 Investment tax credit. (a) This account shall be debited with the amounts of investment tax credits related to service company property...

  10. 30 CFR 256.0 - Authority for information collection.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... OF THE INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas, and Sulphur Management, General § 256.0 Authority for information collection. (a... information collection is “30 CFR part 256, Leasing of Sulphur or Oil and Gas in the Outer Continental Shelf...

  11. 24 CFR 232.256 - Partial payment of claims.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Partial payment of claims. 232.256 Section 232.256 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MORTGAGE AND LOAN...

  12. 24 CFR 232.256 - Partial payment of claims.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Partial payment of claims. 232.256 Section 232.256 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MORTGAGE AND LOAN...

  13. 30 CFR 256.80 - Leases of other minerals.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Leases of other minerals. 256.80 Section 256.80 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE....80 Leases of other minerals. The existence of a lease that meets the requirements of section 6(a) of...

  14. 40 CFR 81.256 - Northeast Iowa Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Northeast Iowa Intrastate Air Quality Control Region. 81.256 Section 81.256 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.256 Northeast Iowa Intrastate Air Quality Control Region. The Northeast Iowa...

  15. 40 CFR 256.42 - Recommendations for assuring facility development.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... development. 256.42 Section 256.42 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Facility... unrestricted movement of solid and hazardous waste across State and local boundaries. ...

  16. Development of 256 x 256 Element Impurity Band Conduction Infrared Detector Arrays for Astronomy

    NASA Technical Reports Server (NTRS)

    Domingo, George

    1997-01-01

    This report describes the work performed on a one and a half year advance technology program to develop Impurity Band Conduction (IBC) detectors with very low dark current, high quantum efficiency, and with good repeatable processes. The program fabricated several epitaxial growths of Si:As detecting layers from 15 to 35 microns thick and analyzed the performance versus the thickness and the Arsenic concentration of these epitaxial layers. Some of the epitaxial runs did not yield because of excessive residual impurities. The thicker epitaxial layers and the ones with higher Arsenic concentration resulted in good detectors with low dark currents and good quantum efficiency. The program hybridized six detector die from the best detector wafers to a low noise, 256 x 256 readout array and delivered the hybrids to NASA Ames for a more detailed study of the performance of the detectors.

  17. 40 CFR 256.22 - Recommendations for State regulatory powers.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Recommendations for State regulatory powers. 256.22 Section 256.22 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste...

  18. 40 CFR 256.22 - Recommendations for State regulatory powers.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Recommendations for State regulatory powers. 256.22 Section 256.22 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste...

  19. 40 CFR 256.21 - Requirements for State regulatory powers.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirements for State regulatory powers. 256.21 Section 256.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste...

  20. 40 CFR 256.21 - Requirements for State regulatory powers.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirements for State regulatory powers. 256.21 Section 256.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste...

  1. 40 CFR 256.20 - Requirements for State legal authority.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirements for State legal authority. 256.20 Section 256.20 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste...

  2. 40 CFR 256.20 - Requirements for State legal authority.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirements for State legal authority. 256.20 Section 256.20 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste...

  3. 40 CFR 256.21 - Requirements for State regulatory powers.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Requirements for State regulatory powers. 256.21 Section 256.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste...

  4. 40 CFR 256.20 - Requirements for State legal authority.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Requirements for State legal authority. 256.20 Section 256.20 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste...

  5. 40 CFR 256.22 - Recommendations for State regulatory powers.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Recommendations for State regulatory powers. 256.22 Section 256.22 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste...

  6. 40 CFR 256.20 - Requirements for State legal authority.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirements for State legal authority. 256.20 Section 256.20 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste...

  7. 40 CFR 256.20 - Requirements for State legal authority.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Requirements for State legal authority. 256.20 Section 256.20 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste...

  8. 28 CFR 25.6 - Accessing records in the system.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Accessing records in the system. 25.6 Section 25.6 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The...) Search the relevant databases (i.e., NICS Index, NCIC, III) for any matching records; and (iv) Provide...

  9. 28 CFR 25.6 - Accessing records in the system.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Accessing records in the system. 25.6 Section 25.6 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The...) Search the relevant databases (i.e., NICS Index, NCIC, III) for any matching records; and (iv) Provide...

  10. 28 CFR 25.6 - Accessing records in the system.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Accessing records in the system. 25.6 Section 25.6 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The...) Search the relevant databases (i.e., NICS Index, NCIC, III) for any matching records; and (iv) Provide...

  11. 28 CFR 25.6 - Accessing records in the system.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Accessing records in the system. 25.6 Section 25.6 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The...) Search the relevant databases (i.e., NICS Index, NCIC, III) for any matching records; and (iv) Provide...

  12. 49 CFR 195.256 - Crossing of railroads and highways.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Crossing of railroads and highways. 195.256... TRANSPORTATION OF HAZARDOUS LIQUIDS BY PIPELINE Construction § 195.256 Crossing of railroads and highways. The pipe at each railroad or highway crossing must be installed so as to adequately withstand the dynamic...

  13. 49 CFR 195.256 - Crossing of railroads and highways.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 3 2012-10-01 2012-10-01 false Crossing of railroads and highways. 195.256... TRANSPORTATION OF HAZARDOUS LIQUIDS BY PIPELINE Construction § 195.256 Crossing of railroads and highways. The pipe at each railroad or highway crossing must be installed so as to adequately withstand the dynamic...

  14. 49 CFR 195.256 - Crossing of railroads and highways.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 3 2011-10-01 2011-10-01 false Crossing of railroads and highways. 195.256... TRANSPORTATION OF HAZARDOUS LIQUIDS BY PIPELINE Construction § 195.256 Crossing of railroads and highways. The pipe at each railroad or highway crossing must be installed so as to adequately withstand the dynamic...

  15. 49 CFR 195.256 - Crossing of railroads and highways.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 3 2014-10-01 2014-10-01 false Crossing of railroads and highways. 195.256... TRANSPORTATION OF HAZARDOUS LIQUIDS BY PIPELINE Construction § 195.256 Crossing of railroads and highways. The pipe at each railroad or highway crossing must be installed so as to adequately withstand the dynamic...

  16. 49 CFR 195.256 - Crossing of railroads and highways.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 3 2013-10-01 2013-10-01 false Crossing of railroads and highways. 195.256... TRANSPORTATION OF HAZARDOUS LIQUIDS BY PIPELINE Construction § 195.256 Crossing of railroads and highways. The pipe at each railroad or highway crossing must be installed so as to adequately withstand the dynamic...

  17. 17 CFR 256.255 - Accumulated deferred investment tax credits.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... investment tax credits. 256.255 Section 256.255 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... investment tax credits. (a) This account shall be credited and account 411.5, Investment tax credit, debited with investment tax credits deferred by companies which do not apply such credits as a reduction of the...

  18. 40 CFR 256.02 - Scope of the State solid waste management plan.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., General Requirements, Definitions § 256.02 Scope of the State solid waste management plan. (a)(1) The... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Scope of the State solid waste management plan. 256.02 Section 256.02 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED...

  19. 40 CFR 256.02 - Scope of the State solid waste management plan.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., General Requirements, Definitions § 256.02 Scope of the State solid waste management plan. (a)(1) The... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Scope of the State solid waste management plan. 256.02 Section 256.02 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED...

  20. 40 CFR 256.02 - Scope of the State solid waste management plan.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., General Requirements, Definitions § 256.02 Scope of the State solid waste management plan. (a)(1) The... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Scope of the State solid waste management plan. 256.02 Section 256.02 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED...

  1. 40 CFR 256.02 - Scope of the State solid waste management plan.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., General Requirements, Definitions § 256.02 Scope of the State solid waste management plan. (a)(1) The... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Scope of the State solid waste management plan. 256.02 Section 256.02 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED...

  2. 40 CFR 256.02 - Scope of the State solid waste management plan.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., General Requirements, Definitions § 256.02 Scope of the State solid waste management plan. (a)(1) The... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Scope of the State solid waste management plan. 256.02 Section 256.02 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED...

  3. 49 CFR 256.11 - Applications.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... execution and be signed by the Chief Executive Officer of the applicant or by the applicant, where the... TRANSPORTATION FINANCIAL ASSISTANCE FOR RAILROAD PASSENGER TERMINALS Regulations Governing Applications for and Disbursement of Financial Assistance § 256.11 Applications. (a) Incorporation by reference in application of...

  4. 37 CFR 256.1 - General.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT ARBITRATION ROYALTY PANEL RULES AND PROCEDURES ADJUSTMENT OF ROYALTY FEE FOR CABLE COMPULSORY LICENSE § 256.1 General. This part establishes adjusted terms and rates for royalty payments in accordance with the provisions of 17...

  5. 15 CFR 256.3 - Procedure.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... PROGRAM § 256.3 Procedure. Arrangements for collaborative research by NIST with a Research Associate generally begin through discussions or correspondence between NIST scientists and representatives of... are followed by the consummation of a Memorandum of Agreement which is signed by NIST, the sponsoring...

  6. 15 CFR 256.3 - Procedure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... PROGRAM § 256.3 Procedure. Arrangements for collaborative research by NIST with a Research Associate generally begin through discussions or correspondence between NIST scientists and representatives of... are followed by the consummation of a Memorandum of Agreement which is signed by NIST, the sponsoring...

  7. 15 CFR 256.3 - Procedure.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... PROGRAM § 256.3 Procedure. Arrangements for collaborative research by NIST with a Research Associate generally begin through discussions or correspondence between NIST scientists and representatives of... are followed by the consummation of a Memorandum of Agreement which is signed by NIST, the sponsoring...

  8. 15 CFR 256.3 - Procedure.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... PROGRAM § 256.3 Procedure. Arrangements for collaborative research by NIST with a Research Associate generally begin through discussions or correspondence between NIST scientists and representatives of... are followed by the consummation of a Memorandum of Agreement which is signed by NIST, the sponsoring...

  9. 15 CFR 256.3 - Procedure.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... PROGRAM § 256.3 Procedure. Arrangements for collaborative research by NIST with a Research Associate generally begin through discussions or correspondence between NIST scientists and representatives of... are followed by the consummation of a Memorandum of Agreement which is signed by NIST, the sponsoring...

  10. 25 CFR 256.24 - Will I need flood insurance?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Will I need flood insurance? 256.24 Section 256.24... Will I need flood insurance? You will need flood insurance if your dwelling is located in an area identified as having special flood hazards under the Flood Disaster Protection Act of 1973 (Pub. L. 93-234...

  11. A 256×256 low-light-level CMOS imaging sensor with digital CDS

    NASA Astrophysics Data System (ADS)

    Zou, Mei; Chen, Nan; Zhong, Shengyou; Li, Zhengfen; Zhang, Jicun; Yao, Li-bin

    2016-10-01

    In order to achieve high sensitivity for low-light-level CMOS image sensors (CIS), a capacitive transimpedance amplifier (CTIA) pixel circuit with a small integration capacitor is used. As the pixel and the column area are highly constrained, it is difficult to achieve analog correlated double sampling (CDS) to remove the noise for low-light-level CIS. So a digital CDS is adopted, which realizes the subtraction algorithm between the reset signal and pixel signal off-chip. The pixel reset noise and part of the column fixed-pattern noise (FPN) can be greatly reduced. A 256×256 CIS with CTIA array and digital CDS is implemented in the 0.35μm CMOS technology. The chip size is 7.7mm×6.75mm, and the pixel size is 15μm×15μm with a fill factor of 20.6%. The measured pixel noise is 24LSB with digital CDS in RMS value at dark condition, which shows 7.8× reduction compared to the image sensor without digital CDS. Running at 7fps, this low-light-level CIS can capture recognizable images with the illumination down to 0.1lux.

  12. 17 CFR 256.01-3 - General structure of accounting system.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... accounting system. 256.01-3 Section 256.01-3 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) UNIFORM SYSTEM OF ACCOUNTS FOR MUTUAL SERVICE COMPANIES AND SUBSIDIARY SERVICE... accounting system. (a) The accounts provided herein are in two general categories: Balance sheet accounts and...

  13. 30 CFR 256.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas, and Sulphur Management, General § 256.1... Secretary of the Interior (Secretary) will exercise the authority to administer a leasing program for oil...

  14. 30 CFR 256.12 - Supplemental sales.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas, and Sulphur Management, General § 256.12 Supplemental sales. (a) The Secretary may conduct a...

  15. 40 CFR 256.06 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... § 256.06 Definitions. Terms not defined below have the meanings assigned them by section 1004 of the Act. The Act means the Solid Waste Disposal Act, as amended by the Resource Conservation and Recovery Act... resource recovery system or component thereof, any system, program or facility for resource conservation...

  16. 40 CFR 256.06 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... § 256.06 Definitions. Terms not defined below have the meanings assigned them by section 1004 of the Act. The Act means the Solid Waste Disposal Act, as amended by the Resource Conservation and Recovery Act... resource recovery system or component thereof, any system, program or facility for resource conservation...

  17. 40 CFR 256.06 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... § 256.06 Definitions. Terms not defined below have the meanings assigned them by section 1004 of the Act. The Act means the Solid Waste Disposal Act, as amended by the Resource Conservation and Recovery Act... resource recovery system or component thereof, any system, program or facility for resource conservation...

  18. 40 CFR 256.06 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... § 256.06 Definitions. Terms not defined below have the meanings assigned them by section 1004 of the Act. The Act means the Solid Waste Disposal Act, as amended by the Resource Conservation and Recovery Act... resource recovery system or component thereof, any system, program or facility for resource conservation...

  19. 40 CFR 256.06 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... § 256.06 Definitions. Terms not defined below have the meanings assigned them by section 1004 of the Act. The Act means the Solid Waste Disposal Act, as amended by the Resource Conservation and Recovery Act... resource recovery system or component thereof, any system, program or facility for resource conservation...

  20. 17 CFR 256.411 - Provision for deferred income taxes-credit.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... taxes-credit. 256.411 Section 256.411 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... deferred income taxes—credit. This account shall be credited and Accumulated Deferred Income Taxes debited with an amount equal to the portion of taxes on income payable for the year which is attributable to a...

  1. 17 CFR 256.01-5 - Determination of service cost accounting.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... accounting. Service at cost and fair allocation of costs require, first of all, an accurate accounting for... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Determination of service cost accounting. 256.01-5 Section 256.01-5 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION...

  2. 42 CFR 422.256 - Review, negotiation, and approval of bids.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 3 2013-10-01 2013-10-01 false Review, negotiation, and approval of bids. 422.256..., and Related Information and Plan Approval § 422.256 Review, negotiation, and approval of bids. (a... aggregate bid amounts submitted under § 422.252 and conduct negotiations with MA organizations regarding...

  3. 42 CFR 422.256 - Review, negotiation, and approval of bids.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 3 2012-10-01 2012-10-01 false Review, negotiation, and approval of bids. 422.256..., and Related Information and Plan Approval § 422.256 Review, negotiation, and approval of bids. (a... aggregate bid amounts submitted under § 422.252 and conduct negotiations with MA organizations regarding...

  4. 42 CFR 422.256 - Review, negotiation, and approval of bids.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 3 2014-10-01 2014-10-01 false Review, negotiation, and approval of bids. 422.256..., and Related Information and Plan Approval § 422.256 Review, negotiation, and approval of bids. (a... aggregate bid amounts submitted under § 422.252 and conduct negotiations with MA organizations regarding...

  5. 40 CFR 97.256 - Account error.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS CAIR SO2 Allowance Tracking System § 97.256... any error in any CAIR SO2 Allowance Tracking System account. Within 10 business days of making such...

  6. 42 CFR 422.256 - Review, negotiation, and approval of bids.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 3 2011-10-01 2011-10-01 false Review, negotiation, and approval of bids. 422.256... Information and Plan Approval § 422.256 Review, negotiation, and approval of bids. (a) Authority. Subject to... submitted under § 422.252 and conduct negotiations with MA organizations regarding these bids (including the...

  7. 42 CFR 422.256 - Review, negotiation, and approval of bids.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Review, negotiation, and approval of bids. 422.256... Information and Plan Approval § 422.256 Review, negotiation, and approval of bids. (a) Authority. Subject to... submitted under § 422.252 and conduct negotiations with MA organizations regarding these bids (including the...

  8. Implementation of cryptographic hash function SHA256 in C++

    NASA Astrophysics Data System (ADS)

    Shrivastava, Akash

    2012-02-01

    This abstract explains the implementation of SHA Secure hash algorithm 256 using C++. The SHA-2 is a strong hashing algorithm used in almost all kinds of security applications. The algorithm consists of 2 phases: Preprocessing and hash computation. Preprocessing involves padding a message, parsing the padded message into m-bits blocks, and setting initialization values to be used in the hash computation. It generates a message schedule from padded message and uses that schedule, along with functions, constants, and word operations to iteratively generate a series of hash values. The final hash value generated by the computation is used to determine the message digest. SHA-2 includes a significant number of changes from its predecessor, SHA-1. SHA-2 consists of a set of four hash functions with digests that are 224, 256, 384 or 512 bits. The algorithm outputs a 256 bits message block with an internal state block of 256 bits and initial block size of 512 bits. Maximum message length in bit is generated is 2^64 -1, over all computed over a series of 64 rounds consisting or several operations such as and, or, Xor, Shr, Rot. The code will provide clear understanding of the hash algorithm and generates hash values to retrieve message digest.

  9. 40 CFR 256.31 - Recommendations for developing and implementing resource conservation and recovery programs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... implementing resource conservation and recovery programs. 256.31 Section 256.31 Protection of Environment... SOLID WASTE MANAGEMENT PLANS Resource Conservation and Resource Recovery Programs § 256.31 Recommendations for developing and implementing resource conservation and recovery programs. (a) In order to...

  10. 40 CFR 256.24 - Recommendations for closing or upgrading open dumps.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Recommendations for closing or upgrading open dumps. 256.24 Section 256.24 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS...

  11. 40 CFR 256.24 - Recommendations for closing or upgrading open dumps.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Recommendations for closing or upgrading open dumps. 256.24 Section 256.24 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS...

  12. 40 CFR 256.23 - Requirements for closing or upgrading open dumps.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirements for closing or upgrading open dumps. 256.23 Section 256.23 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid...

  13. 40 CFR 256.23 - Requirements for closing or upgrading open dumps.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirements for closing or upgrading open dumps. 256.23 Section 256.23 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid...

  14. 40 CFR 256.23 - Requirements for closing or upgrading open dumps.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Requirements for closing or upgrading open dumps. 256.23 Section 256.23 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid...

  15. 40 CFR 256.24 - Recommendations for closing or upgrading open dumps.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Recommendations for closing or upgrading open dumps. 256.24 Section 256.24 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS...

  16. 40 CFR 256.05 - Annual work program.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 256.05 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Purpose, General Requirements... implementation of the State plan. ...

  17. 40 CFR 256.05 - Annual work program.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 256.05 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Purpose, General Requirements... implementation of the State plan. ...

  18. 17 CFR 256.01-2 - Application to service companies doing business with nonassociate companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... COMPANIES AND SUBSIDIARY SERVICE COMPANIES, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 General Instructions § 256.01-2 Application to service companies doing business with nonassociate companies. While this... companies doing business with nonassociate companies. 256.01-2 Section 256.01-2 Commodity and Securities...

  19. AQP2 Plasma Membrane Diffusion Is Altered by the Degree of AQP2-S256 Phosphorylation

    PubMed Central

    Arnspang, Eva C.; Login, Frédéric H.; Koffman, Jennifer S.; Sengupta, Prabuddha; Nejsum, Lene N.

    2016-01-01

    Fine tuning of urine concentration occurs in the renal collecting duct in response to circulating levels of arginine vasopressin (AVP). AVP stimulates intracellular cAMP production, which mediates exocytosis of sub-apical vesicles containing the water channel aquaporin-2 (AQP2). Protein Kinase A (PKA) phosphorylates AQP2 on serine-256 (S256), which triggers plasma membrane accumulation of AQP2. This mediates insertion of AQP2 into the apical plasma membrane, increasing water permeability of the collecting duct. AQP2 is a homo-tetramer. When S256 on all four monomers is changed to the phosphomimic aspartic acid (S256D), AQP2-S256D localizes to the plasma membrane and internalization is decreased. In contrast, when S256 is mutated to alanine (S256A) to mimic non-phosphorylated AQP2, AQP2-S256A localizes to intracellular vesicles as well as the plasma membrane, with increased internalization from the plasma membrane. S256 phosphorylation is not necessary for exocytosis and dephosphorylation is not necessary for endocytosis, however, the degree of S256 phosphorylation is hypothesized to regulate the kinetics of AQP2 endocytosis and thus, retention time in the plasma membrane. Using k-space Image Correlation Spectroscopy (kICS), we determined how the number of phosphorylated to non-phosphorylated S256 monomers in the AQP2 tetramer affects diffusion speed of AQP2 in the plasma membrane. When all four monomers mimicked constitutive phosphorylation (AQP2-S256D), diffusion was faster than when all four were non-phosphorylated (AQP2-S256A). AQP2-WT diffused at a speed similar to that of AQP2-S256D. When an average of two or three monomers in the tetramer were constitutively phosphorylated, the average diffusion coefficients were not significantly different to that of AQP2-S256D. However, when only one monomer was phosphorylated, diffusion was slower and similar to AQP2-S256A. Thus, AQP2 with two to four phosphorylated monomers has faster plasma membrane kinetics, than the

  20. AQP2 Plasma Membrane Diffusion Is Altered by the Degree of AQP2-S256 Phosphorylation.

    PubMed

    Arnspang, Eva C; Login, Frédéric H; Koffman, Jennifer S; Sengupta, Prabuddha; Nejsum, Lene N

    2016-10-28

    Fine tuning of urine concentration occurs in the renal collecting duct in response to circulating levels of arginine vasopressin (AVP). AVP stimulates intracellular cAMP production, which mediates exocytosis of sub-apical vesicles containing the water channel aquaporin-2 (AQP2). Protein Kinase A (PKA) phosphorylates AQP2 on serine-256 (S256), which triggers plasma membrane accumulation of AQP2. This mediates insertion of AQP2 into the apical plasma membrane, increasing water permeability of the collecting duct. AQP2 is a homo-tetramer. When S256 on all four monomers is changed to the phosphomimic aspartic acid (S256D), AQP2-S256D localizes to the plasma membrane and internalization is decreased. In contrast, when S256 is mutated to alanine (S256A) to mimic non-phosphorylated AQP2, AQP2-S256A localizes to intracellular vesicles as well as the plasma membrane, with increased internalization from the plasma membrane. S256 phosphorylation is not necessary for exocytosis and dephosphorylation is not necessary for endocytosis, however, the degree of S256 phosphorylation is hypothesized to regulate the kinetics of AQP2 endocytosis and thus, retention time in the plasma membrane. Using k-space Image Correlation Spectroscopy (kICS), we determined how the number of phosphorylated to non-phosphorylated S256 monomers in the AQP2 tetramer affects diffusion speed of AQP2 in the plasma membrane. When all four monomers mimicked constitutive phosphorylation (AQP2-S256D), diffusion was faster than when all four were non-phosphorylated (AQP2-S256A). AQP2-WT diffused at a speed similar to that of AQP2-S256D. When an average of two or three monomers in the tetramer were constitutively phosphorylated, the average diffusion coefficients were not significantly different to that of AQP2-S256D. However, when only one monomer was phosphorylated, diffusion was slower and similar to AQP2-S256A. Thus, AQP2 with two to four phosphorylated monomers has faster plasma membrane kinetics, than the

  1. 40 CFR 256.41 - Recommendations for assessing the need for facilities.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommendations for assessing the need for facilities. 256.41 Section 256.41 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... their impact on facility needs should be assessed. (3) Current and projected movement of solid and...

  2. 40 CFR 256.41 - Recommendations for assessing the need for facilities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommendations for assessing the need for facilities. 256.41 Section 256.41 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... their impact on facility needs should be assessed. (3) Current and projected movement of solid and...

  3. 30 CFR 256.10 - Information to States.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas, and Sulphur Management, General § 256.10 Information to States. (a) The information covered...

  4. 31 CFR 256.31 - How does FMS compute interest on payments?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false How does FMS compute interest on payments? 256.31 Section 256.31 Money and Finance: Treasury Regulations Relating to Money and Finance... compute interest on payments? FMS computes interest according to the terms of the statute that waives...

  5. 40 CFR 256.62 - Requirements for public participation in State regulatory development.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirements for public participation in State regulatory development. 256.62 Section 256.62 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  6. 40 CFR 256.62 - Requirements for public participation in State regulatory development.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Requirements for public participation in State regulatory development. 256.62 Section 256.62 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  7. 40 CFR 256.62 - Requirements for public participation in State regulatory development.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirements for public participation in State regulatory development. 256.62 Section 256.62 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  8. 40 CFR 256.62 - Requirements for public participation in State regulatory development.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirements for public participation in State regulatory development. 256.62 Section 256.62 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  9. 40 CFR 256.62 - Requirements for public participation in State regulatory development.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Requirements for public participation in State regulatory development. 256.62 Section 256.62 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  10. 17 CFR 256.308 - Office furniture and equipment.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... UTILITY HOLDING COMPANY ACT OF 1935 Service Company Property Accounts § 256.308 Office furniture and... equipment, accounting machines, electronic claculators, typewriters and other mechanical office equipment. ...

  11. 17 CFR 256.308 - Office furniture and equipment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... UTILITY HOLDING COMPANY ACT OF 1935 Service Company Property Accounts § 256.308 Office furniture and... equipment, accounting machines, electronic claculators, typewriters and other mechanical office equipment. ...

  12. 30 CFR 256.44 - Bids disqualified.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... prior production period with an average daily production in excess of 1.6 million barrels of crude oil, natural gas and liquified petroleum products and has not filed a Statement of Production as required by... or refused to file a detailed report of production when required to do so under § 256.46(g) of this...

  13. 17 CFR 256.01-13 - Submission of questions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... UTILITY HOLDING COMPANY ACT OF 1935 General Instructions § 256.01-13 Submission of questions. To promote... consideration and decision. Balance Sheet Accounts: Assets and Other Debit Accounts 1. service company property ...

  14. 17 CFR 256.426.5 - Other deductions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... deductible before determining total income before interest charges. (b) Records shall be so maintained by...) UNIFORM SYSTEM OF ACCOUNTS FOR MUTUAL SERVICE COMPANIES AND SUBSIDIARY SERVICE COMPANIES, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Income and Expense Accounts § 256.426.5 Other deductions. (a) This account...

  15. 17 CFR 256.305 - Structures and improvements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... provided for machinery, apparatus, or other equipment of the company shall be charged to the same account... (CONTINUED) UNIFORM SYSTEM OF ACCOUNTS FOR MUTUAL SERVICE COMPANIES AND SUBSIDIARY SERVICE COMPANIES, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Service Company Property Accounts § 256.305 Structures and...

  16. 17 CFR 256.136 - Temporary cash investments.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Temporary cash investments... UTILITY HOLDING COMPANY ACT OF 1935 3. Current and Accrued Assets § 256.136 Temporary cash investments. This account shall include the cost of investments, such as demand and time loans, bankers' acceptances...

  17. 17 CFR 256.136 - Temporary cash investments.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Temporary cash investments... UTILITY HOLDING COMPANY ACT OF 1935 3. Current and Accrued Assets § 256.136 Temporary cash investments. This account shall include the cost of investments, such as demand and time loans, bankers' acceptances...

  18. 20 CFR 632.256 - Submission of applications.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.256 Submission of applications. To the extent possible, Native American grantees will be notified of their summer youth allocation at the same time section 401 allocations are announced. The summer plan will be a...

  19. 20 CFR 632.256 - Submission of applications.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.256 Submission of applications. To the extent possible, Native American grantees will be notified of their summer youth allocation at the same time section 401 allocations are announced. The summer plan will be a...

  20. 20 CFR 632.256 - Submission of applications.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.256 Submission of applications. To the extent possible, Native American grantees will be notified of their summer youth allocation at the same time section 401 allocations are announced. The summer plan will be a...

  1. 17 CFR 256.215 - Appropriated retained earnings.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Appropriated retained earnings... UTILITY HOLDING COMPANY ACT OF 1935 Liabilities and Other Credit Accounts § 256.215 Appropriated retained earnings. This account shall include the amount of retained earnings which has been appropriated or set...

  2. 40 CFR 256.64 - Requirements for public participation in the open dump inventory.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirements for public participation in the open dump inventory. 256.64 Section 256.64 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  3. 40 CFR 256.63 - Requirements for public participation in the permitting of facilities.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Requirements for public participation in the permitting of facilities. 256.63 Section 256.63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  4. 40 CFR 256.64 - Requirements for public participation in the open dump inventory.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirements for public participation in the open dump inventory. 256.64 Section 256.64 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  5. 40 CFR 256.64 - Requirements for public participation in the open dump inventory.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirements for public participation in the open dump inventory. 256.64 Section 256.64 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  6. 40 CFR 256.63 - Requirements for public participation in the permitting of facilities.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirements for public participation in the permitting of facilities. 256.63 Section 256.63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  7. 40 CFR 256.63 - Requirements for public participation in the permitting of facilities.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirements for public participation in the permitting of facilities. 256.63 Section 256.63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  8. 40 CFR 256.64 - Requirements for public participation in the open dump inventory.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Requirements for public participation in the open dump inventory. 256.64 Section 256.64 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  9. 40 CFR 256.63 - Requirements for public participation in the permitting of facilities.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirements for public participation in the permitting of facilities. 256.63 Section 256.63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  10. 40 CFR 256.64 - Requirements for public participation in the open dump inventory.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Requirements for public participation in the open dump inventory. 256.64 Section 256.64 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  11. 40 CFR 256.60 - Requirements for public participation in State and substate plans.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Requirements for public participation in State and substate plans. 256.60 Section 256.60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  12. 30 CFR 256.0 - Authority for information collection.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas, and... part 256, Leasing of Sulphur or Oil and Gas in the Outer Continental Shelf.” (b) MMS collects this...

  13. 30 CFR 256.8 - Leasing maps and diagrams.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas, and Sulphur Management, General § 256.8 Leasing maps and diagrams. (a) Any area of the OCS...

  14. 40 CFR 256.60 - Requirements for public participation in State and substate plans.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Requirements for public participation in State and substate plans. 256.60 Section 256.60 Protection of Environment ENVIRONMENTAL PROTECTION... shall: (1) Publicize information in news media having broad audiences in the geographic area; (2) Place...

  15. 40 CFR 256.60 - Requirements for public participation in State and substate plans.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirements for public participation in State and substate plans. 256.60 Section 256.60 Protection of Environment ENVIRONMENTAL PROTECTION... shall: (1) Publicize information in news media having broad audiences in the geographic area; (2) Place...

  16. 40 CFR 256.60 - Requirements for public participation in State and substate plans.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirements for public participation in State and substate plans. 256.60 Section 256.60 Protection of Environment ENVIRONMENTAL PROTECTION... shall: (1) Publicize information in news media having broad audiences in the geographic area; (2) Place...

  17. 40 CFR 256.60 - Requirements for public participation in State and substate plans.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirements for public participation in State and substate plans. 256.60 Section 256.60 Protection of Environment ENVIRONMENTAL PROTECTION... shall: (1) Publicize information in news media having broad audiences in the geographic area; (2) Place...

  18. 17 CFR 256.01-4 - Construction or service contracts, and centralized procurement accounting.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... expenses directly attributable to construction work shall be excluded from the accounting system of the... companies. Cost of goods procured shall be excluded from the accounting system of the service company and... contracts, and centralized procurement accounting. 256.01-4 Section 256.01-4 Commodity and Securities...

  19. 27 CFR 25.6 - Delegations of the Administrator.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., DEPARTMENT OF THE TREASURY ALCOHOL BEER Scope of Regulations § 25.6 Delegations of the Administrator. The... 27 CFR Part 25, Beer. You may obtain a copy of this order by accessing the TTB Web site (http://www...

  20. 27 CFR 25.6 - Delegations of the Administrator.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., DEPARTMENT OF THE TREASURY LIQUORS BEER Scope of Regulations § 25.6 Delegations of the Administrator. The... 27 CFR Part 25, Beer. You may obtain a copy of this order by accessing the TTB Web site (http://www...

  1. 27 CFR 25.6 - Delegations of the Administrator.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., DEPARTMENT OF THE TREASURY ALCOHOL BEER Scope of Regulations § 25.6 Delegations of the Administrator. The... 27 CFR Part 25, Beer. You may obtain a copy of this order by accessing the TTB Web site (http://www...

  2. 27 CFR 25.6 - Delegations of the Administrator.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., DEPARTMENT OF THE TREASURY LIQUORS BEER Scope of Regulations § 25.6 Delegations of the Administrator. The... 27 CFR Part 25, Beer. You may obtain a copy of this order by accessing the TTB Web site (http://www...

  3. 27 CFR 25.6 - Delegations of the Administrator.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., DEPARTMENT OF THE TREASURY LIQUORS BEER Scope of Regulations § 25.6 Delegations of the Administrator. The... 27 CFR Part 25, Beer. You may obtain a copy of this order by accessing the TTB Web site (http://www...

  4. 40 CFR 256.31 - Recommendations for developing and implementing resource conservation and recovery programs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Recommendations for developing and implementing resource conservation and recovery programs. 256.31 Section 256.31 Protection of Environment... are identified. These studies should review various technological approaches, environmental...

  5. 40 CFR 256.31 - Recommendations for developing and implementing resource conservation and recovery programs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Recommendations for developing and implementing resource conservation and recovery programs. 256.31 Section 256.31 Protection of Environment... are identified. These studies should review various technological approaches, environmental...

  6. 40 CFR 256.31 - Recommendations for developing and implementing resource conservation and recovery programs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Recommendations for developing and implementing resource conservation and recovery programs. 256.31 Section 256.31 Protection of Environment... are identified. These studies should review various technological approaches, environmental...

  7. 40 CFR 256.31 - Recommendations for developing and implementing resource conservation and recovery programs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommendations for developing and implementing resource conservation and recovery programs. 256.31 Section 256.31 Protection of Environment... are identified. These studies should review various technological approaches, environmental...

  8. 40 CFR 256.61 - Requirements for public participation in the annual State work program.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirements for public participation in the annual State work program. 256.61 Section 256.61 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  9. 40 CFR 256.61 - Requirements for public participation in the annual State work program.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirements for public participation in the annual State work program. 256.61 Section 256.61 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  10. 40 CFR 256.61 - Requirements for public participation in the annual State work program.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirements for public participation in the annual State work program. 256.61 Section 256.61 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  11. 40 CFR 256.61 - Requirements for public participation in the annual State work program.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Requirements for public participation in the annual State work program. 256.61 Section 256.61 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  12. 40 CFR 256.61 - Requirements for public participation in the annual State work program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Requirements for public participation in the annual State work program. 256.61 Section 256.61 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE...

  13. 17 CFR 256.108 - Accumulated provision for depreciation and amortization of service company property.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., unless the company maintains costs and related reserves for specific units or types of property. (c... depreciation and amortization of service company property. 256.108 Section 256.108 Commodity and Securities... COMPANIES AND SUBSIDIARY SERVICE COMPANIES, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Balance Sheet...

  14. Design and Development of 256x256 Linear Mode Low-Noise Avalanche Photodiode Arrays

    NASA Technical Reports Server (NTRS)

    Yuan, Ping; Sudharsanan, Rengarajan; Bai, Xiaogang; Boisvert, Joseph; McDonald, Paul; Chang, James

    2011-01-01

    A larger format photodiode array is always desirable for many LADAR imaging applications. However, as the array format increases, the laser power or the lens aperture has to increase to maintain the same flux per pixel thus increasing the size, weight and power of the imaging system. In order to avoid this negative impact, it is essential to improve the pixel sensitivity. The sensitivity of a short wavelength infrared linear-mode avalanche photodiode (APD) is a delicate balance of quantum efficiency, usable gain, excess noise factor, capacitance, and dark current of APD as well as the input equivalent noise of the amplifier. By using InA1As as a multiplication layer in an InP-based APD, the ionization coefficient ratio, k, is reduced from 0.40 (lnP) to 0.22, and the excess noise is reduced by about 50%. An additional improvement in excess noise of 25% was achieved by employing an impact-ionization-engineering structure with a k value of 0.15. Compared with the traditional InP structure, about 30% reduction in the noise-equivalent power with the following amplifier can be achieved. Spectrolab demonstrated 30-um mesa APD pixels with a dark current less than 10 nA and a capacitance of 60 fF at gain of 10. APD gain uninformity determines the usable gain of most pixels in an array, which is critical to focal plane array sensitivity. By fine tuning the material growth and device process, a break-down-voltage standard deviation of 0.1 V and gain of 30 on individual pixels were demonstrated in our 256x256 linear-mode APD arrays.

  15. 40 CFR 256.65 - Recommendations for public participation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommendations for public... Participation § 256.65 Recommendations for public participation. (a) State and substate planning agencies should establish an advisory group, or utilize an existing group, to provide recommendations on major policy and...

  16. 49 CFR Appendix A to Part 256 - Certificate

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Certificate A Appendix A to Part 256 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... therein are true and correct to the best of his knowledge, information and belief. [43 FR 21890, May 22...

  17. 49 CFR Appendix A to Part 256 - Certificate

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Certificate A Appendix A to Part 256 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... therein are true and correct to the best of his knowledge, information and belief. [43 FR 21890, May 22...

  18. 49 CFR Appendix A to Part 256 - Certificate

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Certificate A Appendix A to Part 256 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... therein are true and correct to the best of his knowledge, information and belief. [43 FR 21890, May 22...

  19. 49 CFR Appendix A to Part 256 - Certificate

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Certificate A Appendix A to Part 256 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... therein are true and correct to the best of his knowledge, information and belief. [43 FR 21890, May 22...

  20. 49 CFR Appendix A to Part 256 - Certificate

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Certificate A Appendix A to Part 256 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... therein are true and correct to the best of his knowledge, information and belief. [43 FR 21890, May 22...

  1. 17 CFR 256.152 - Fuel stock expenses undistributed.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Fuel stock expenses... (CONTINUED) UNIFORM SYSTEM OF ACCOUNTS FOR MUTUAL SERVICE COMPANIES AND SUBSIDIARY SERVICE COMPANIES, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 3. Current and Accrued Assets § 256.152 Fuel stock expenses...

  2. 17 CFR 256.926 - Employee pensions and benefits.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Employee pensions and benefits... UTILITY HOLDING COMPANY ACT OF 1935 2. Expense § 256.926 Employee pensions and benefits. This account... employee benefit programs such as medical and surgical benefits, disability benefits, life insurance...

  3. 24 CFR 213.256 - Premiums; insurance upon completion.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Premiums; insurance upon completion... HOUSING AND URBAN DEVELOPMENT MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES COOPERATIVE HOUSING MORTGAGE INSURANCE Contract Rights and Obligations-Projects § 213.256 Premiums...

  4. Field gamma-ray spectrometer GS256: measurements stability

    NASA Astrophysics Data System (ADS)

    Mojzeš, Andrej

    2009-01-01

    The stability of in situ readings of the portable gamma-ray spectrometer GS256 during the field season of 2006 was studied. The instrument is an impulse detector of gamma rays based on NaI(Tl) 3" × 3" scintillation unit and 256-channel spectral analyzer which allows simultaneous assessment of up to 8 radioisotopes in rocks. It is commonly used in surface geophysical survey for the measurement of natural 40K, 238U and 232Th but also artificial 137Cs quantities. The statistical evaluation is given of both repeated measurements - in the laboratory and at several field control points in different survey areas. The variability of values shows both the instrument stability and also the relative influence of some meteorological factors, mainly rainfalls. The analysis shows an acceptable level of instrument measurements stability, the necessity to avoid measurement under unfavourable meteorological conditions and to keep detailed field book information about time, position and work conditions.

  5. 25 CFR 256.26 - Can I receive Housing Improvement Program services if I am living in a mobile home?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... am living in a mobile home? 256.26 Section 256.26 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE... I am living in a mobile home? Yes. If you meet the eligibility criteria in § 256.6 and there is... § 256.7. If you require Category B services and your mobile home has exterior walls of less than three...

  6. 42 CFR 447.256 - Procedures for CMS action on assurances and State plan amendments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... plan amendments. 447.256 Section 447.256 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES... action on assurances and State plan amendments. (a) Criteria for approval. (1) CMS approval action on State plans and State plan amendments, is taken in accordance with subpart B of part 430 of this chapter...

  7. 42 CFR 447.256 - Procedures for CMS action on assurances and State plan amendments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... plan amendments. 447.256 Section 447.256 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES... action on assurances and State plan amendments. (a) Criteria for approval. (1) CMS approval action on State plans and State plan amendments, is taken in accordance with subpart B of part 430 of this chapter...

  8. 25 CFR 256.20 - How are these repairs or construction trades persons, home building contractors, or construction...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false How are these repairs or construction trades persons, home building contractors, or construction companies selected and paid? 256.20 Section 256.20 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HOUSING HOUSING IMPROVEMENT PROGRAM § 256.20 How are these repairs or construction trades persons...

  9. 17 CFR 256.930.1 - General advertising expenses.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false General advertising expenses... UTILITY HOLDING COMPANY ACT OF 1935 2. Expense § 256.930.1 General advertising expenses. This account shall include the cost of materials used and expenses incurred in advertising and related activities...

  10. 17 CFR 256.930.1 - General advertising expenses.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false General advertising expenses... UTILITY HOLDING COMPANY ACT OF 1935 2. Expense § 256.930.1 General advertising expenses. This account shall include the cost of materials used and expenses incurred in advertising and related activities...

  11. 17 CFR 256.403 - Depreciation and amortization expense.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Depreciation and amortization... UTILITY HOLDING COMPANY ACT OF 1935 Income and Expense Accounts § 256.403 Depreciation and amortization expense. This account shall include the amount of depreciation and amortization for all service plant, and...

  12. 17 CFR 256.01-11 - Methods of allocation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) UNIFORM SYSTEM OF ACCOUNTS FOR MUTUAL SERVICE COMPANIES AND SUBSIDIARY SERVICE COMPANIES, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 General Instructions § 256.01-11 Methods of allocation. Indirect costs and compensation for use of capital shall be allocated to work orders in accordance with the service company's...

  13. 17 CFR 256.921 - Office supplies and expenses.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Office supplies and expenses... UTILITY HOLDING COMPANY ACT OF 1935 2. Expense § 256.921 Office supplies and expenses. (a) This account shall include office supplies and expenses incurred in connection with the general administration of...

  14. 31 CFR 256.41 - When is reimbursement due for CDA and No FEAR payments?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... No FEAR payments? 256.41 Section 256.41 Money and Finance: Treasury Regulations Relating to Money and... When is reimbursement due for CDA and No FEAR payments? Reimbursement for a CDA or No FEAR payment... Management (OPM) regulations, No FEAR reimbursements or payment reimbursement plans must be made within 45...

  15. 31 CFR 256.13 - Are agencies required to supply a taxpayer identification number (TIN) when submitting a request...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... taxpayer identification number (TIN) when submitting a request for payment? 256.13 Section 256.13 Money and... BILLS Requesting Payments § 256.13 Are agencies required to supply a taxpayer identification number (TIN) when submitting a request for payment? Yes, agencies must include a valid TIN on all requests for...

  16. 31 CFR 256.13 - Are agencies required to supply a taxpayer identification number (TIN) when submitting a request...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... taxpayer identification number (TIN) when submitting a request for payment? 256.13 Section 256.13 Money and... BILLS Requesting Payments § 256.13 Are agencies required to supply a taxpayer identification number (TIN) when submitting a request for payment? Yes, agencies must include a valid TIN on all requests for...

  17. 31 CFR 256.13 - Are agencies required to supply a taxpayer identification number (TIN) when submitting a request...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... taxpayer identification number (TIN) when submitting a request for payment? 256.13 Section 256.13 Money and... BILLS Requesting Payments § 256.13 Are agencies required to supply a taxpayer identification number (TIN) when submitting a request for payment? Yes, agencies must include a valid TIN on all requests for...

  18. 31 CFR 256.13 - Are agencies required to supply a taxpayer identification number (TIN) when submitting a request...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... taxpayer identification number (TIN) when submitting a request for payment? 256.13 Section 256.13 Money and... BILLS Requesting Payments § 256.13 Are agencies required to supply a taxpayer identification number (TIN) when submitting a request for payment? Yes, agencies must include a valid TIN on all requests for...

  19. 31 CFR 256.13 - Are agencies required to supply a taxpayer identification number (TIN) when submitting a request...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... taxpayer identification number (TIN) when submitting a request for payment? 256.13 Section 256.13 Money and... BILLS Requesting Payments § 256.13 Are agencies required to supply a taxpayer identification number (TIN) when submitting a request for payment? Yes, agencies must include a valid TIN on all requests for...

  20. 30 CFR 256.72 - Compensatory payments as production.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Assignments, Transfers, and Extensions § 256.72 Compensatory payments as production. If an oil and gas lessee makes compensatory payments and if the lease is not being maintained in force by other production of oil or gas in...

  1. 17 CFR 256.421 - Miscellaneous income or loss.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Miscellaneous income or loss... UTILITY HOLDING COMPANY ACT OF 1935 Income and Expense Accounts § 256.421 Miscellaneous income or loss. This account shall include all income or loss items not provided for elsewhere. (Secs. 13, 15, 20, 49...

  2. 40 CFR 256.42 - Recommendations for assuring facility development.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Facility Planning and Implementation § 256.42 Recommendations for assuring facility development. (a) The State plan... facilities, and (4) Development of schedules of implementation. (d) The State plan should encourage private...

  3. 40 CFR 256.42 - Recommendations for assuring facility development.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Facility Planning and Implementation § 256.42 Recommendations for assuring facility development. (a) The State plan... facilities, and (4) Development of schedules of implementation. (d) The State plan should encourage private...

  4. 40 CFR 256.42 - Recommendations for assuring facility development.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Facility Planning and Implementation § 256.42 Recommendations for assuring facility development. (a) The State plan... facilities, and (4) Development of schedules of implementation. (d) The State plan should encourage private...

  5. 49 CFR 256.13 - Review and approval of applications.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... local public and private investment, by transportation carriers and others, in improved intercity and local public transportation facilities and services; (7) Encourage the preservation of railroad... 49 Transportation 4 2010-10-01 2010-10-01 false Review and approval of applications. 256.13...

  6. 50 CFR 216.256 - Applications for Letters of Authorization.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND IMPORTING OF MARINE MAMMALS Taking Marine Mammals Incidental to Conducting Precision Strike Weapon Missions in the Gulf of Mexico § 216.256 Applications for Letters of Authorization. To incidentally take...

  7. 30 CFR 256.58 - Termination of the period of liability and cancellation of a bond.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... provide an alternative form of security, and the Regional Director determines that the alternative form of... cancellation of a bond. 256.58 Section 256.58 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION... retain other forms of security as shown in the following table: For the following type of bond The period...

  8. 24 CFR 3282.256 - Distributor or retailer complaint handling.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) Where a distributor or retailer receives a consumer complaint or other information concerning a... 24 Housing and Urban Development 5 2014-04-01 2014-04-01 false Distributor or retailer complaint... Distributor Responsibilities § 3282.256 Distributor or retailer complaint handling. (a) When a distributor or...

  9. 24 CFR 3282.256 - Distributor or dealer complaint handling.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) Where a distributor or dealer receives a consumer complaint or other information concerning a... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false Distributor or dealer complaint... Distributor Responsibilities § 3282.256 Distributor or dealer complaint handling. (a) When a distributor or...

  10. 24 CFR 3282.256 - Distributor or dealer complaint handling.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) Where a distributor or dealer receives a consumer complaint or other information concerning a... 24 Housing and Urban Development 5 2012-04-01 2012-04-01 false Distributor or dealer complaint... Distributor Responsibilities § 3282.256 Distributor or dealer complaint handling. (a) When a distributor or...

  11. 24 CFR 3282.256 - Distributor or dealer complaint handling.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) Where a distributor or dealer receives a consumer complaint or other information concerning a... 24 Housing and Urban Development 5 2013-04-01 2013-04-01 false Distributor or dealer complaint... Distributor Responsibilities § 3282.256 Distributor or dealer complaint handling. (a) When a distributor or...

  12. 24 CFR 3282.256 - Distributor or dealer complaint handling.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Where a distributor or dealer receives a consumer complaint or other information concerning a... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Distributor or dealer complaint... Distributor Responsibilities § 3282.256 Distributor or dealer complaint handling. (a) When a distributor or...

  13. 17 CFR 256.188 - Research, development, or demonstration expenditures.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Research, development, or... COMPANIES, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 4. Deferred Debits § 256.188 Research, development, or... of all expenditures for research, development or demonstration undertaken by or sponsored through the...

  14. 25 CFR 256.28 - What can I do if I disagree with actions taken under the Housing Improvement Program?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Housing Improvement Program? 256.28 Section 256.28 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HOUSING HOUSING IMPROVEMENT PROGRAM § 256.28 What can I do if I disagree with actions taken under the Housing Improvement Program? You may appeal action or inaction by an official of the Bureau of...

  15. 42 CFR 441.256 - Additional condition for Federal financial participation (FFP).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... LIMITS APPLICABLE TO SPECIFIC SERVICES Sterilizations § 441.256 Additional condition for Federal financial participation (FFP). (a) FFP is not available in expenditures for any sterilization or...

  16. 40 CFR 256.27 - Recommendation for schedules leading to compliance with the prohibition of open dumping.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Recommendation for schedules leading to compliance with the prohibition of open dumping. 256.27 Section 256.27 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE...

  17. 40 CFR 256.27 - Recommendation for schedules leading to compliance with the prohibition of open dumping.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Recommendation for schedules leading to compliance with the prohibition of open dumping. 256.27 Section 256.27 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE...

  18. 40 CFR 256.26 - Requirement for schedules leading to compliance with the prohibition of open dumping.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Requirement for schedules leading to compliance with the prohibition of open dumping. 256.26 Section 256.26 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE...

  19. 40 CFR 256.26 - Requirement for schedules leading to compliance with the prohibition of open dumping.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirement for schedules leading to compliance with the prohibition of open dumping. 256.26 Section 256.26 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE...

  20. 40 CFR 256.27 - Recommendation for schedules leading to compliance with the prohibition of open dumping.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Recommendation for schedules leading to compliance with the prohibition of open dumping. 256.27 Section 256.27 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE...

  1. 40 CFR 256.26 - Requirement for schedules leading to compliance with the prohibition of open dumping.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirement for schedules leading to compliance with the prohibition of open dumping. 256.26 Section 256.26 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE...

  2. 30 CFR 250.256 - What related facilities and operations information must accompany the DPP or DOCD?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What related facilities and operations information must accompany the DPP or DOCD? 250.256 Section 250.256 Mineral Resources MINERALS MANAGEMENT... SHELF Plans and Information Contents of Development and Production Plans (dpp) and Development...

  3. Osteoporosis‐like Changes in Walker Carcinoma 256‐Bearing Rats, Not Accompanied with Hypercalcemia or Parathyroid Hormone‐related Protein Production

    PubMed Central

    Waki, Yoshihiro; Kasugai, Shohei; Ohya, Keiichi

    1995-01-01

    Walker carcinoma 256 (W256) was reported to induce hypercalcemia dependent on bone metastasis and/or parathyroid hormone‐related protein (PTHrP) in the rat, providing a model of the humoral hypercalcemia of malignancy. In this study, after the subcutaneous inoculation of cells of the W256/S line, which is maintained in this laboratory, into young female Wistar Imamichi rats (6 weeks old), serum calcium and phosphorus levels changed only within the control range, whereas serum alkaline phosphatase activity and urinary calcium level significantly increased and urinary phosphorus decreased during the tumor growth, resulting in hypercalciuria and hypophosphaturia. W256/S did not express PTHrP‐mRNA, whereas LLC‐W256 cells did express it. Serum PTHrP level was not changed in W256/S‐bearing rats. Osteoporosis‐like changes, bone weight loss, low contents of bone calcium and phosphorus, and a decrease in the bone mineral density (BMD), were observed in the femur 14 days after the tumor inoculation. There was a pronounced decrease in the serum 17β‐estradiol level during the tumor growth. The reduction of BMD of femurs in W256/S‐bearing rats was significantly inhibited by treatment with salmon calcitonin or 17β‐estradiol. On the basis of these results, W256/S carcinoma‐bearing rats seem to be a useful model for osteoporosis of hypoovarianism. PMID:7540609

  4. 17 CFR 256.408 - Taxes other than income taxes.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Taxes other than income taxes... UTILITY HOLDING COMPANY ACT OF 1935 Income and Expense Accounts § 256.408 Taxes other than income taxes. (a) This account shall include the amount of state unemployment insurance, franchise taxes, federal...

  5. 30 CFR 250.256 - What related facilities and operations information must accompany the DPP or DOCD?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What related facilities and operations information must accompany the DPP or DOCD? 250.256 Section 250.256 Mineral Resources BUREAU OF OCEAN ENERGY... OPERATIONS IN THE OUTER CONTINENTAL SHELF Plans and Information Contents of Development and Production Plans...

  6. l-Glutamine supplementation promotes an improved energetic balance in Walker-256 tumor-bearing rats.

    PubMed

    Martins, Heber Amilcar; Bazotte, Roberto Barbosa; Vicentini, Geraldo Emilio; Lima, Mariana Machado; Guarnier, Flavia Alessandra; Hermes-Uliana, Catchia; Frez, Flavia Cristina Vieira; Bossolani, Gleison Daion Piovezana; Fracaro, Luciane; Fávaro, Larissa Dos Santos; Manzano, Mariana Inocêncio; Zanoni, Jacqueline Nelisis

    2017-03-01

    We evaluated the effects of supplementation with oral l-glutamine in Walker-256 tumor-bearing rats. A total of 32 male Wistar rats aged 54 days were randomly divided into four groups: rats without Walker-256 tumor, that is, control rats (C group); control rats supplemented with l-glutamine (CG group); Walker-256 tumor rats without l-glutamine supplementation (WT group); and WT rats supplemented with l-glutamine (WTG group). l-Glutamine was incorporated into standard food at a proportion of 2 g/100 g (2%). After 10 days of the experimental period, the jejunum and duodenum were removed and processed. Protein expression levels of key enzymes of gluconeogenesis, that is, phosphoenolpyruvate carboxykinase and glucose-6-phosphatase, were analyzed by western blot and immunohistochemical techniques. In addition, plasma corticosterone, glucose, insulin, and urea levels were evaluated. The WTG group showed significantly increased plasma glucose and insulin levels ( p < 0.05); however, plasma corticosterone and urea remained unchanged. Moreover, the WTG group showed increased immunoreactive staining for jejunal phosphoenolpyruvate carboxykinase and increased expression of duodenal glucose-6-phosphatase. Furthermore, the WTG group presented with less intense cancer cachexia and slower tumor growth. These results could be attributed, at least partly, to increased intestinal gluconeogenesis and insulinemia, and better glycemia maintenance during fasting in Walker-256 tumor rats on a diet supplemented with l-glutamine.

  7. 256. Photocopy of drawing (1975 piping drawing by the Ralph ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    256. Photocopy of drawing (1975 piping drawing by the Ralph M. Parsons Company) LIQUID OXYGEN FLOW DIAGRAM FOR THE LSB AREA, SHEET P-2 - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 East, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  8. 30 CFR 256.20 - Consideration of coastal zone management program.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Consideration of coastal zone management... SHELF Oil and Gas Leasing Program § 256.20 Consideration of coastal zone management program. In the development of the leasing program, consideration shall be given to the coastal zone management program being...

  9. 46 CFR 153.256 - Trunks, domes, and openings of cargo tanks.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Equipment Cargo Tanks § 153.256 Trunks, domes, and openings of cargo tanks. (a) The hatch of a cargo tank... uppermost part of the tank, extending above the weatherdeck; (2) Its hatch at the top of the trunk or dome...

  10. 46 CFR 153.256 - Trunks, domes, and openings of cargo tanks.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Equipment Cargo Tanks § 153.256 Trunks, domes, and openings of cargo tanks. (a) The hatch of a cargo tank... uppermost part of the tank, extending above the weatherdeck; (2) Its hatch at the top of the trunk or dome...

  11. 46 CFR 153.256 - Trunks, domes, and openings of cargo tanks.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Equipment Cargo Tanks § 153.256 Trunks, domes, and openings of cargo tanks. (a) The hatch of a cargo tank... uppermost part of the tank, extending above the weatherdeck; (2) Its hatch at the top of the trunk or dome...

  12. 46 CFR 153.256 - Trunks, domes, and openings of cargo tanks.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Equipment Cargo Tanks § 153.256 Trunks, domes, and openings of cargo tanks. (a) The hatch of a cargo tank... uppermost part of the tank, extending above the weatherdeck; (2) Its hatch at the top of the trunk or dome...

  13. 46 CFR 153.256 - Trunks, domes, and openings of cargo tanks.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Equipment Cargo Tanks § 153.256 Trunks, domes, and openings of cargo tanks. (a) The hatch of a cargo tank... uppermost part of the tank, extending above the weatherdeck; (2) Its hatch at the top of the trunk or dome...

  14. The oophorectomy effect on Walker 256 tumor inoculated into the vagina and uterine cervix of female rats.

    PubMed

    Brito, Nara Macedo Botelho; Carvalho, Rita de Kássia Vidigal; Matos, Lia Tavares de Moura Brasil; Lobato, Rodolfo Costa; Brito, Rosângela Baía

    2009-01-01

    Verify the effect of oophorectomy on the evolution of the Walker 256 tumor inoculated into the vagina and cervix of female rats. Ten Wistar, female rats were used, distributed into two groups with 05 animals each: Tumor group (TG): Rats inoculated with Walker 256 tumor; Oophorectomy group (OG): oophorectomized rats inoculated with Walker 256 tumor. The day before the tumor vaginal inoculation, acetic acid was inoculated into the vaginas of both groups of rats; the following day, the vaginal walls were scarified with an endocervix brush, and then Walker 256 tumor was inoculated. After 12 days, the tumor was removed together with the vagina and uterine horns for macro and microscopic analyses. The data were submitted to statistical analyses. There was no statistical difference between the two groups; however it was observed that the behavior of tumor growth on the OG group presented greater invasion, compromising the uterine horns. The results of the study on the GO group presented a macroscopic behavior different from the TG group, however, both of them presented similar development in terms of tumor mass.

  15. Differential Fault Analysis on CLEFIA with 128, 192, and 256-Bit Keys

    NASA Astrophysics Data System (ADS)

    Takahashi, Junko; Fukunaga, Toshinori

    This paper describes a differential fault analysis (DFA) attack against CLEFIA. The proposed attack can be applied to CLEFIA with all supported keys: 128, 192, and 256-bit keys. DFA is a type of side-channel attack. This attack enables the recovery of secret keys by injecting faults into a secure device during its computation of the cryptographic algorithm and comparing the correct ciphertext with the faulty one. CLEFIA is a 128-bit blockcipher with 128, 192, and 256-bit keys developed by the Sony Corporation in 2007. CLEFIA employs a generalized Feistel structure with four data lines. We developed a new attack method that uses this characteristic structure of the CLEFIA algorithm. On the basis of the proposed attack, only 2 pairs of correct and faulty ciphertexts are needed to retrieve the 128-bit key, and 10.78 pairs on average are needed to retrieve the 192 and 256-bit keys. The proposed attack is more efficient than any previously reported. In order to verify the proposed attack and estimate the calculation time to recover the secret key, we conducted an attack simulation using a PC. The simulation results show that we can obtain each secret key within three minutes on average. This result shows that we can obtain the entire key within a feasible computational time.

  16. A comparative study of Message Digest 5(MD5) and SHA256 algorithm

    NASA Astrophysics Data System (ADS)

    Rachmawati, D.; Tarigan, J. T.; Ginting, A. B. C.

    2018-03-01

    The document is a collection of written or printed data containing information. The more rapid advancement of technology, the integrity of a document should be kept. Because of the nature of an open document means the document contents can be read and modified by many parties so that the integrity of the information as a content of the document is not preserved. To maintain the integrity of the data, it needs to create a mechanism which is called a digital signature. A digital signature is a specific code which is generated from the function of producing a digital signature. One of the algorithms that used to create the digital signature is a hash function. There are many hash functions. Two of them are message digest 5 (MD5) and SHA256. Those both algorithms certainly have its advantages and disadvantages of each. The purpose of this research is to determine the algorithm which is better. The parameters which used to compare that two algorithms are the running time and complexity. The research results obtained from the complexity of the Algorithms MD5 and SHA256 is the same, i.e., ⊖ (N), but regarding the speed is obtained that MD5 is better compared to SHA256.

  17. 17 CFR 256.309 - Automobiles, other vehicles, and related garage equipment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Automobiles, other vehicles... § 256.309 Automobiles, other vehicles, and related garage equipment. This account shall include the delivered cost of all service company owned automobiles, vans, trucks, and other vehicles used by the...

  18. 17 CFR 256.309 - Automobiles, other vehicles, and related garage equipment.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Automobiles, other vehicles... § 256.309 Automobiles, other vehicles, and related garage equipment. This account shall include the delivered cost of all service company owned automobiles, vans, trucks, and other vehicles used by the...

  19. 40 CFR 256.24 - Recommendations for closing or upgrading open dumps.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste Disposal Programs § 256.24 Recommendations for closing or upgrading open dumps. (a) All... feasibility of resource recovery or resource conservation to reduce the solid waste volume entering a facility...

  20. 40 CFR 256.24 - Recommendations for closing or upgrading open dumps.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste Disposal Programs § 256.24 Recommendations for closing or upgrading open dumps. (a) All... feasibility of resource recovery or resource conservation to reduce the solid waste volume entering a facility...

  1. 40 CFR 264.256 - Special requirements for ignitable or reactive waste.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., AND DISPOSAL FACILITIES Waste Piles § 264.256 Special requirements for ignitable or reactive waste. Ignitable or reactive waste must not be placed in a waste pile unless the waste and waste pile satisfy all... immediately after placement in the pile so that: (1) The resulting waste, mixture, or dissolution of material...

  2. 40 CFR 265.256 - Special requirements for ignitable or reactive waste.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... TREATMENT, STORAGE, AND DISPOSAL FACILITIES Waste Piles § 265.256 Special requirements for ignitable or reactive waste. (a) Ignitable or reactive waste must not be placed in a pile unless the waste and pile satisfy all applicable requirements of 40 CFR part 268, and: (1) Addition of the waste to an existing pile...

  3. 29 CFR 779.256 - Conditions for enterprise coverage of gasoline service establishments.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Conditions for enterprise coverage of gasoline service... Apply; Enterprise Coverage The Gasoline Service Establishment Enterprise § 779.256 Conditions for enterprise coverage of gasoline service establishments. (a) The requirement that the enterprise must be “an...

  4. 29 CFR 779.256 - Conditions for enterprise coverage of gasoline service establishments.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Conditions for enterprise coverage of gasoline service... Apply; Enterprise Coverage The Gasoline Service Establishment Enterprise § 779.256 Conditions for enterprise coverage of gasoline service establishments. (a) The requirement that the enterprise must be “an...

  5. 29 CFR 779.256 - Conditions for enterprise coverage of gasoline service establishments.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Conditions for enterprise coverage of gasoline service... Apply; Enterprise Coverage The Gasoline Service Establishment Enterprise § 779.256 Conditions for enterprise coverage of gasoline service establishments. (a) The requirement that the enterprise must be “an...

  6. 29 CFR 779.256 - Conditions for enterprise coverage of gasoline service establishments.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 3 2014-07-01 2014-07-01 false Conditions for enterprise coverage of gasoline service... Apply; Enterprise Coverage The Gasoline Service Establishment Enterprise § 779.256 Conditions for enterprise coverage of gasoline service establishments. (a) The requirement that the enterprise must be “an...

  7. 29 CFR 779.256 - Conditions for enterprise coverage of gasoline service establishments.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Conditions for enterprise coverage of gasoline service... Apply; Enterprise Coverage The Gasoline Service Establishment Enterprise § 779.256 Conditions for enterprise coverage of gasoline service establishments. (a) The requirement that the enterprise must be “an...

  8. One-stop shop assessment for atrial septal defect closure using 256-slice coronary CT angiography.

    PubMed

    Yamasaki, Yuzo; Nagao, Michinobu; Kawanami, Satoshi; Kamitani, Takeshi; Sagiyama, Koji; Yamanouchi, Torahiko; Sakamoto, Ichiro; Yamamura, Kenichiro; Yabuuchi, Hidetake; Honda, Hiroshi

    2017-02-01

    To investigate the feasibility and accuracy of measurement of the pulmonary to systemic blood flow ratio (Qp/Qs) and defect and rim sizes in secundum atrial septal defects (ASDs) using 256-slice CT, compared to the reference transoesophageal echocardiography (TEE) and right heart catheterization (RHC) measurements. Twenty-three consecutive adult patients with secundum ASDs who underwent retrospective ECG-gated coronary CT angiography (CCTA), TEE and RHC were enrolled in this study. Right ventricular (RV) and left ventricular (LV) stroke volumes (SV) were calculated by biventricular volumetry of CCTA. Qp/Qs-CT was defined as RVSV/LVSV. The sizes of the defect and rim were measured by multi-planar reconstruction CT images. Correlations between Qp/Qs-CT and Qp/Qs-RHC and between the defect diameter obtained by CT and TEE were analyzed by Pearson's coefficient analysis. Rim sizes by CT and TEE were compared by paired t-test. Qp/Qs-CT was significantly correlated with Qp/Qs-RHC (r = 0.83, p < 0.0001), and the defect diameter by CT was significantly correlated with that by TEE (r = 0.95, p < 0.0001). There was no significant difference between CT and TEE in measurements of rim size. 256-slice CCTA allows measuring Qp/Qs and size of defects and rims in patients with secundum ASDs, accomplishing pretreatment evaluation non-invasively and comprehensively. • Quantification of left-to-right shunting can be performed reliably and accurately by CT. • The sizes of defects and rims can be measured accurately using 256-slice CT. • 256-slice CT permits pretreatment evaluation of ASD non-invasively and comprehensively.

  9. 32 CFR 256.6 - Runway classification by aircraft type.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Runway classification by aircraft type. 256.6... type. Class A runways S-2, VC-6, C-1, C-2, TC-4C, U-10, U-11, LU-16, TU-16, HU-16, C-7, C-8, C-12, C-47...-130, A-7, A-38, AV-8, P-2, P-3, T-29, T-33, T-37, T-39, T-1, HC-130B, C-131, C-140, C-5A, KC-97, F-9...

  10. 32 CFR 256.6 - Runway classification by aircraft type.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Runway classification by aircraft type. 256.6... type. Class A runways S-2, VC-6, C-1, C-2, TC-4C, U-10, U-11, LU-16, TU-16, HU-16, C-7, C-8, C-12, C-47...-130, A-7, A-38, AV-8, P-2, P-3, T-29, T-33, T-37, T-39, T-1, HC-130B, C-131, C-140, C-5A, KC-97, F-9...

  11. 25 CFR 256.6 - Am I eligible for the Housing Improvement Program?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Section 256.6 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HOUSING HOUSING IMPROVEMENT... Improvement Program if: (a) You are a member of a Federally recognized American Indian tribe or Alaska Native... percent of the Department of Health and Human Services poverty income guidelines. These guidelines are...

  12. 31 CFR 256.33 - For what period of time is interest computed under 31 U.S.C. 1304(b)?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false For what period of time is interest computed under 31 U.S.C. 1304(b)? 256.33 Section 256.33 Money and Finance: Treasury Regulations Relating to....33 For what period of time is interest computed under 31 U.S.C. 1304(b)? Interest is computed from...

  13. METALLOPROTEINS DURING DEVELOPMENT OF WALKER-256 CARCINOSARCOMA RESISTANT PHENOTYPE.

    PubMed

    Chekhun, V F; Lozovska, Yu V; Burlaka, A P; Ganusevich, I I; Shvets, Yu V; Lukianova, N Yu; Todor, I M; Demash, D V; Pavlova, A A; Naleskina, L A

    2015-01-01

    The study was focused on the detection of changes in serum and tumor metal-containing proteins in animals during development ofdoxorubicin-resistant phenotype in malignant cells after 12 courses of chemotherapy. We found that on every stage of resistance development there was a significant increase in content of ferritin and transferrin proteins (which take part in iron traffick and storage) in Walker-256 carc'inosarcoma tissue. We observed decreased serumferritin levels at the beginning stage of the resistance development and significant elevation of this protein levels in the cases withfully developed resistance phenotype. Transferrin content showed changes opposite to that offerritin. During the development of resistance phenotype the tumor tissue also exhibited increased 'free iron' concentration that putatively correlate with elevation of ROS generation and levels of MMP-2 and MMP-9 active forms. The tumor non-protein thiol content increases gradually as well. The serum of animals with early stages of resistance phenotype development showed high ceruloplasmin activity and its significant reduction after loss of tumor sensitivity to doxorubicin. Therefore, the development of resistance phenotype in Walker-256 carcinosarcoma is accompanied by both the deregulation of metal-containing proteins in serum and tumor tissue and by the changes in activity of antioxidant defense system. Thus, the results of this study allow us to determine the spectrum of metal-containing proteins that are involved in the development of resistant tumor phenotype and that may be targeted for methods for doxorubicin sensitivity correction therapy.

  14. Performance of Trellis Coded 256 QAM super-multicarrier modem VLSI's for SDH interface outage-free digital microwave radio

    NASA Astrophysics Data System (ADS)

    Aikawa, Satoru; Nakamura, Yasuhisa; Takanashi, Hitoshi

    1994-02-01

    This paper describes the performance of an outage free SXH (Synchronous Digital Hierarchy) interface 256 QAM modem. An outage free DMR (Digital Microwave Radio) is achieved by a high coding gain trellis coded SPORT QAM and Super Multicarrier modem. A new frame format and its associated circuits connect the outage free modem to the SDH interface. The newly designed VLSI's are key devices for developing the modem. As an overall modem performance, BER (bit error rate) characteristics and equipment signatures are presented. A coding gain of 4.7 dB (at a BER of 10(exp -4)) is obtained using SPORT 256 QAM and Viterbi decoding. This coding gain is realized by trellis coding as well as by increasing of transmission rate. Roll-off factor is decreased to maintain the same frequency occupation and modulation level as ordinary SDH 256 QAM modern.

  15. 24 CFR 221.256 - Interest rate increase and payment of mortgage insurance premiums on mortgages under § 221.60 and...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... of mortgage insurance premiums on mortgages under § 221.60 and § 221.65. 221.256 Section 221.256... Interest rate increase and payment of mortgage insurance premiums on mortgages under § 221.60 and § 221.65.... (c) The liability for payment of mortgage insurance premiums shall begin on and be computed from the...

  16. 19 CFR 10.256 - Maintenance of records and submission of Certificate by importer.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED... Certain Other Non-Textile Articles § 10.256 Maintenance of records and submission of Certificate by importer. (a) Maintenance of records. Each importer claiming preferential treatment for an article under...

  17. 19 CFR 10.256 - Maintenance of records and submission of Certificate by importer.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED... Certain Other Non-Textile Articles § 10.256 Maintenance of records and submission of Certificate by importer. (a) Maintenance of records. Each importer claiming preferential treatment for an article under...

  18. 19 CFR 10.256 - Maintenance of records and submission of Certificate by importer.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED... Certain Other Non-Textile Articles § 10.256 Maintenance of records and submission of Certificate by importer. (a) Maintenance of records. Each importer claiming preferential treatment for an article under...

  19. 19 CFR 10.256 - Maintenance of records and submission of Certificate by importer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED... Certain Other Non-Textile Articles § 10.256 Maintenance of records and submission of Certificate by importer. (a) Maintenance of records. Each importer claiming preferential treatment for an article under...

  20. 19 CFR 10.256 - Maintenance of records and submission of Certificate by importer.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED... Certain Other Non-Textile Articles § 10.256 Maintenance of records and submission of Certificate by importer. (a) Maintenance of records. Each importer claiming preferential treatment for an article under...

  1. Decay properties of 256-339Ds superheavy nuclei

    NASA Astrophysics Data System (ADS)

    Santhosh, K. P.; Nithya, C.

    2017-09-01

    The decay properties of 84 isotopes of darmstadtium superheavy nuclei ( Z = 110) have been studied using various theoretical models. The proton emission half-lives, the alpha decay half-lives, the spontaneous fission half-lives and the cluster decay half-lives of all the isotopes are evaluated. The one-proton emission half-lives and the alpha decay half-lives are predicted using the Coulomb and proximity potential model for deformed nuclei (CPPMDN). The calculated alpha half-lives are compared with the available experimental results as well as with the predictions of other theoretical models. The predicted half-lives matches well with the experimental results. The one-proton half-lives are also compared with the predictions using other formalisms. The shell-effect-dependent formula of Santhosh et al. has been employed for calculating the spontaneous fission half-lives. A theoretical comparison of spontaneous fission half-lives with four different formalisms is performed. By comparing the one-proton emission half-lives, the alpha decay half-lives and the spontaneous fission half-lives decay modes are predicted for all the isotopes of Ds. It is seen that the isotopes within the range 256 ≤ A ≤ 263 and 279 ≤ A ≤ 339 decay through spontaneous fission and the isotopes 264 ≤ A ≤ 278 exhibit alpha decay. Cluster decay half-lives are calculated using different models including the Coulomb and proximity potential (CPPM), for determining the magicities in the superheavy region. The effect of magicity at N = 184 and N = 202 were confirmed from the plot of log_{10}T_{1/2} versus neutron number of the daughter nuclei for the emission of different clusters. We hope that the systematic and detailed study of all the possible decay modes of 256-339Ds using various theoretical models will be helpful in the experimental identification of the isotopes of the element in the future.

  2. 256. Linn Cove Viaduct. This is the first precast concrete ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    256. Linn Cove Viaduct. This is the first precast concrete segmental concrete segmental viaduct to be built with the progressive method in the United States. It contains nearly every type of highway construction within its length. With is super elevation of up to ten degrees and its tight horizontal and spiral curves, it was the most complicated bridge of its type built to that time. Looking south-southwest. - Blue Ridge Parkway, Between Shenandoah National Park & Great Smoky Mountains, Asheville, Buncombe County, NC

  3. 25 CFR 256.14 - What are the steps that must be taken to process my application for the Housing Improvement Program?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... to process my application for the Housing Improvement Program? (a) The servicing housing office must... 25 Indians 1 2010-04-01 2010-04-01 false What are the steps that must be taken to process my application for the Housing Improvement Program? 256.14 Section 256.14 Indians BUREAU OF INDIAN AFFAIRS...

  4. 30 CFR 256.70 - Extension of lease by drilling or well reworking operations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Extension of lease by drilling or well..., DEPARTMENT OF THE INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Assignments, Transfers, and Extensions § 256.70 Extension of lease by drilling or well reworking operations...

  5. 30 CFR 256.70 - Extension of lease by drilling or well reworking operations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Extension of lease by drilling or well..., DEPARTMENT OF THE INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Assignments, Transfers, and Extensions § 256.70 Extension of lease by drilling or well reworking operations...

  6. 30 CFR 256.70 - Extension of lease by drilling or well reworking operations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Extension of lease by drilling or well..., DEPARTMENT OF THE INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Assignments, Transfers, and Extensions § 256.70 Extension of lease by drilling or well reworking operations...

  7. Increase in IS256 transposition in invasive vancomycin heteroresistant Staphylococcus aureus isolate belonging to ST100 and its derived VISA mutants.

    PubMed

    Di Gregorio, Sabrina; Fernandez, Silvina; Perazzi, Beatriz; Bello, Natalia; Famiglietti, Angela; Mollerach, Marta

    2016-09-01

    In Staphylococcus aureus, transposition of IS256 has been described to play an important role in biofilm formation and antibiotic resistance. This study describes the molecular characterization of two clinical heterogeneous vancomycin-intermediate S. aureus (hVISA) isolates recovered from the same patient (before and after antibiotic treatment) and two VISA derivatives obtained by serial passages in the presence of vancomycin. Our results showed that antibiotic treatment (in vivo and in vitro) could enhance IS256 transposition, being responsible for the eventual loss of agr function. As far as we know this is the first study that reports the increase of IS256 transposition in isogenic strains after antibiotic treatment in a clinical setting. Copyright © 2016 Elsevier B.V. All rights reserved.

  8. 40 CFR 256.27 - Recommendation for schedules leading to compliance with the prohibition of open dumping.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste Disposal Programs § 256.27 Recommendation for schedules leading...

  9. 40 CFR 256.27 - Recommendation for schedules leading to compliance with the prohibition of open dumping.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste Disposal Programs § 256.27 Recommendation for schedules leading...

  10. 40 CFR 256.26 - Requirement for schedules leading to compliance with the prohibition of open dumping.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste Disposal Programs § 256.26 Requirement for schedules leading to...

  11. 40 CFR 256.26 - Requirement for schedules leading to compliance with the prohibition of open dumping.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Solid Waste Disposal Programs § 256.26 Requirement for schedules leading to...

  12. 47 CFR 25.256 - Special Requirements for operations in the 3.65-3.7 GHz band.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) COMMON CARRIER SERVICES SATELLITE COMMUNICATIONS Technical Standards § 25.256 Special Requirements for....65-3.7 GHz band must negotiate in good faith with that terrestrial licensee to arrive at mutually...

  13. 47 CFR 25.256 - Special Requirements for operations in the 3.65-3.7 GHz band.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) COMMON CARRIER SERVICES SATELLITE COMMUNICATIONS Technical Standards § 25.256 Special Requirements for....65-3.7 GHz band must negotiate in good faith with that terrestrial licensee to arrive at mutually...

  14. General Description of the Compact Digital Ionospheric Sounder Digisonde 256. Revised

    DTIC Science & Technology

    1981-12-01

    channels upper bit phases 1i 16 channels lower bit phases P3 Maximum Method Options = 0 No birdie, no channel toss-out, no ARTIST , no film = 1 bit Birdie... ARTIST output (without 14 and 15) = l bit 4, 5, 6, 7, 12, 13, 14, 15 Film output with 10 sec ,delayed start P4 Printer Cleaning Threshold * 0 No...function for the autoscaled foF2 parameter based on the evaluation of 256 non-spread ionograms from January 1980, Goose Bay, Labrador. For more than

  15. 42 CFR 447.256 - Procedures for CMS action on assurances and State plan amendments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Procedures for CMS action on assurances and State... for Inpatient Hospital and Long-Term Care Facility Services Payment Rates § 447.256 Procedures for CMS action on assurances and State plan amendments. (a) Criteria for approval. (1) CMS approval action on...

  16. Metabolic changes during development of Walker-256 carcinosarcoma resistance to doxorubicin.

    PubMed

    Todor, I N; Lukyanova, N Yu; Shvets, Yu V; Lozovska, Yu V; Chekhun, V F

    2015-03-01

    To study indices of energy metabolism, content of K(+) and Mg(++) both in peripheral blood and in Walker-256 carcinosarcoma during development of resistance to doxorubicin. Resistance of Walker-256 carcinosarcoma to doxorubicin has been developed through 12 subsequent transplantations of tumor after the chemotherapy. Parental strain was inhibited by drug by 65%, while transitional resistant substrains - by 30% and 2%, respectively. Determination of biochemical indices in blood serum and homogenates of tumor tissue, level of potassium, magnesium, lactate, glucose, activities of lactate dehydrogenase and glucose-6-phosphate dehydrogenase was performed with the help of biochemical and immune-enzyme analyzer GBG ChemWell 2990 (USA) using standard kits. Polarography was used to determine indices of mitochondrial oxidative phosphorylation. Study of mitochondrial membrane potential was carried out on flow cytometer Beckman Coulter Epics XL using dye JC-1. It has been determined that development of drug resistance causes the decrease of K(+), Mg(++), glucose content in blood serum and increase of these indices in tumor tissue. At the same time, gradual tumor's loss of sensitivity is characterized by decrease of glycolysis activity in it and activation of mitochondrial oxidative phosphorylation and pentose phosphate pathway of glucose degradation, which causes more intensive formation of NADPH. Development of drug resistance of tumor causes certain metabolic changes in organism and tumor. Further study of such changes will make possible to determine tumor and extratumor markers of resistance.

  17. Supplementation with L-glutamine prevents tumor growth and cancer-induced cachexia as well as restores cell proliferation of intestinal mucosa of Walker-256 tumor-bearing rats.

    PubMed

    Martins, Heber Amilcar; Sehaber, Camila Caviquioli; Hermes-Uliana, Catchia; Mariani, Fernando Augusto; Guarnier, Flavia Alessandra; Vicentini, Geraldo Emílio; Bossolani, Gleison Daion Piovezana; Jussani, Laraine Almeida; Lima, Mariana Machado; Bazotte, Roberto Barbosa; Zanoni, Jacqueline Nelisis

    2016-12-01

    This study aimed to evaluate the intestinal mucosa of the duodenum and jejunum of Walker-256 tumor-bearing rats supplemented with L-glutamine. Thirty-two male 50-day-old Wistar rats (Rattus norvegicus) were randomly divided into four groups: control (C), control supplemented with 2 % L-glutamine (GC), Walker-256 tumor (WT), and Walker-256 tumor supplemented with 2 % L-glutamine (TWG). Walker-256 tumor was induced by inoculation viable tumor cells in the right rear flank. After 10 days, celiotomy was performed and duodenal and jejunal tissues were removed and processed. We evaluated the cachexia index, proliferation index, villus height, crypt depth, total height of the intestinal wall, and number of goblet cells by the technique of periodic acid-Schiff (PAS). Induction of Walker-256 tumor promoted a reduction of metaphase index in the TW group animals, which was accompanied by a reduction in the villous height and crypt depths, resulting in atrophy of the intestinal wall as well as increased PAS-positive goblet cells. Supplementation with L-glutamine reduced the tumor growth and inhibited the development of the cachectic syndrome in animals of the TWG group. Furthermore, amino acid supplementation promoted beneficial effects on the intestinal mucosa in the TWG animals through restoration of the number of PAS-positive goblet cells. Therefore, supplementation with 2 % L-glutamine exhibited a promising role in the prevention of tumor growth and cancer-associated cachexia as well as restoring the intestinal mucosa in the duodenum and jejunum of Walker-256 tumor-bearing rats.

  18. Aerobic Exercise Training Attenuates Tumor Growth and Reduces Insulin Secretion in Walker 256 Tumor-Bearing Rats

    PubMed Central

    Moreira, Veridiana Mota; da Silva Franco, Claudinéia Conationi; Prates, Kelly Valério; Gomes, Rodrigo Mello; de Moraes, Ana Maria Praxedes; Ribeiro, Tatiane Aparecida; Martins, Isabela Peixoto; Previate, Carina; Pavanello, Audrei; Matiusso, Camila Cristina Ianoni; Almeida, Douglas Lopes; Francisco, Flávio Andrade; Malta, Ananda; Tófolo, Laize Peron; da Silva Silveira, Sandra; Saavedra, Lucas Paulo Jacinto; Machado, Katia; da Silva, Paulo Henrique Olivieri; Fabrício, Gabriel S.; Palma-Rigo, Kesia; de Souza, Helenir Medri; de Fátima Silva, Flaviane; Biazi, Giuliana Regina; Pereira, Taís Susane; Vieira, Elaine; Miranda, Rosiane Aparecida; de Oliveira, Júlio Cezar; da Costa Lima, Luiz Delmar; Rinaldi, Wilson; Ravanelli, Maria Ida; de Freitas Mathias, Paulo Cezar

    2018-01-01

    Aerobic exercise training can improve insulin sensitivity in many tissues; however, the relationship among exercise, insulin, and cancer cell growth is unclear. We tested the hypothesis that aerobic exercise training begun during adolescence can attenuate Walker 256 tumor growth in adult rats and alter insulin secretion. Thirty-day-old male Wistar rats engaged in treadmill running for 8 weeks, 3 days/week, 44 min/day, at 55–65% VO2max until they were 90 days old (TC, Trained Control). An equivalently aged group was kept inactive during the same period (SC, Sedentary Control). Then, half the animals of the SC and TC groups were reserved as the control condition and the other half were inoculated with Walker 256 cancer cells, yielding two additional groups (Sedentary Walker and Trained Walker). Zero mortalities were observed in tumor-bearing rats. Body weight (BW), food intake, plasma glucose, insulin levels, and peripheral insulin sensitivity were analyzed before and after tumor cell inoculation. We also evaluated tumor growth, metastasis and cachexia. Isolated pancreatic islets secretory activity was analyzed. In addition, we evaluated mechanic sensibility. Our results showed improved physical performance according to the final workload and VO2max and reduced BW in trained rats at the end of the running protocol. Chronic adaptation to the aerobic exercise training decreased tumor weight, cachexia and metastasis and were associated with low glucose and insulin levels and high insulin sensitivity before and after tumor cell inoculation. Aerobic exercise started at young age also reduced pancreatic islet insulin content and insulin secretion in response to a glucose stimulus, without impairing islet morphology in trained rats. Walker 256 tumor-bearing sedentary rats also presented reduced pancreatic islet insulin content, without changing insulin secretion through isolated pancreatic islets. The mechanical sensitivity test indicated that aerobic exercise training

  19. Aerobic Exercise Training Attenuates Tumor Growth and Reduces Insulin Secretion in Walker 256 Tumor-Bearing Rats.

    PubMed

    Moreira, Veridiana Mota; da Silva Franco, Claudinéia Conationi; Prates, Kelly Valério; Gomes, Rodrigo Mello; de Moraes, Ana Maria Praxedes; Ribeiro, Tatiane Aparecida; Martins, Isabela Peixoto; Previate, Carina; Pavanello, Audrei; Matiusso, Camila Cristina Ianoni; Almeida, Douglas Lopes; Francisco, Flávio Andrade; Malta, Ananda; Tófolo, Laize Peron; da Silva Silveira, Sandra; Saavedra, Lucas Paulo Jacinto; Machado, Katia; da Silva, Paulo Henrique Olivieri; Fabrício, Gabriel S; Palma-Rigo, Kesia; de Souza, Helenir Medri; de Fátima Silva, Flaviane; Biazi, Giuliana Regina; Pereira, Taís Susane; Vieira, Elaine; Miranda, Rosiane Aparecida; de Oliveira, Júlio Cezar; da Costa Lima, Luiz Delmar; Rinaldi, Wilson; Ravanelli, Maria Ida; de Freitas Mathias, Paulo Cezar

    2018-01-01

    Aerobic exercise training can improve insulin sensitivity in many tissues; however, the relationship among exercise, insulin, and cancer cell growth is unclear. We tested the hypothesis that aerobic exercise training begun during adolescence can attenuate Walker 256 tumor growth in adult rats and alter insulin secretion. Thirty-day-old male Wistar rats engaged in treadmill running for 8 weeks, 3 days/week, 44 min/day, at 55-65% VO 2max until they were 90 days old (TC, Trained Control). An equivalently aged group was kept inactive during the same period (SC, Sedentary Control). Then, half the animals of the SC and TC groups were reserved as the control condition and the other half were inoculated with Walker 256 cancer cells, yielding two additional groups (Sedentary Walker and Trained Walker). Zero mortalities were observed in tumor-bearing rats. Body weight (BW), food intake, plasma glucose, insulin levels, and peripheral insulin sensitivity were analyzed before and after tumor cell inoculation. We also evaluated tumor growth, metastasis and cachexia. Isolated pancreatic islets secretory activity was analyzed. In addition, we evaluated mechanic sensibility. Our results showed improved physical performance according to the final workload and VO 2max and reduced BW in trained rats at the end of the running protocol. Chronic adaptation to the aerobic exercise training decreased tumor weight, cachexia and metastasis and were associated with low glucose and insulin levels and high insulin sensitivity before and after tumor cell inoculation. Aerobic exercise started at young age also reduced pancreatic islet insulin content and insulin secretion in response to a glucose stimulus, without impairing islet morphology in trained rats. Walker 256 tumor-bearing sedentary rats also presented reduced pancreatic islet insulin content, without changing insulin secretion through isolated pancreatic islets. The mechanical sensitivity test indicated that aerobic exercise training

  20. Use of LC-MS/MS and Bayes' theorem to identify protein kinases that phosphorylate aquaporin-2 at Ser256.

    PubMed

    Bradford, Davis; Raghuram, Viswanathan; Wilson, Justin L L; Chou, Chung-Lin; Hoffert, Jason D; Knepper, Mark A; Pisitkun, Trairak

    2014-07-15

    In the renal collecting duct, binding of AVP to the V2 receptor triggers signaling changes that regulate osmotic water transport. Short-term regulation of water transport is dependent on vasopressin-induced phosphorylation of aquaporin-2 (AQP2) at Ser256. The protein kinase that phosphorylates this site is not known. We use Bayes' theorem to rank all 521 rat protein kinases with regard to the likelihood of a role in Ser256 phosphorylation on the basis of prior data and new experimental data. First, prior probabilities were estimated from previous transcriptomic and proteomic profiling data, kinase substrate specificity data, and evidence for kinase regulation by vasopressin. This ranking was updated using new experimental data describing the effects of several small-molecule kinase inhibitors with known inhibitory spectra (H-89, KN-62, KN-93, and GSK-650394) on AQP2 phosphorylation at Ser256 in inner medullary collecting duct suspensions. The top-ranked kinase was Ca2+/calmodulin-dependent protein kinase II (CAMK2), followed by protein kinase A (PKA) and protein kinase B (AKT). Liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based in vitro phosphorylation studies compared the ability of three highly ranked kinases to phosphorylate AQP2 and other inner medullary collecting duct proteins, PKA, CAMK2, and serum/glucocorticoid-regulated kinase (SGK). All three proved capable of phosphorylating AQP2 at Ser256, although CAMK2 and PKA were more potent than SGK. The in vitro phosphorylation experiments also identified candidate protein kinases for several additional phosphoproteins with likely roles in collecting duct regulation, including Nedd4-2, Map4k4, and 3-phosphoinositide-dependent protein kinase 1. We conclude that Bayes' theorem is an effective means of integrating data from multiple data sets in physiology.

  1. Lamellipodia and Membrane Blebs Drive Efficient Electrotactic Migration of Rat Walker Carcinosarcoma Cells WC 256.

    PubMed

    Sroka, Jolanta; Krecioch, Izabela; Zimolag, Eliza; Lasota, Slawomir; Rak, Monika; Kedracka-Krok, Sylwia; Borowicz, Pawel; Gajek, Marta; Madeja, Zbigniew

    2016-01-01

    The endogenous electric field (EF) may provide an important signal for directional cell migration during wound healing, embryonic development and cancer metastasis but the mechanism of cell electrotaxis is poorly understood. Additionally, there is no research addressing the question on the difference in electrotactic motility of cells representing various strategies of cell movement-specifically blebbing vs. lamellipodial migration. In the current study we constructed a unique experimental model which allowed for the investigation of electrotactic movement of cells of the same origin but representing different modes of cell migration: weakly adherent, spontaneously blebbing (BC) and lamellipodia forming (LC) WC256 cells. We report that both BC and LC sublines show robust cathodal migration in a physiological EF (1-3 V/cm). The directionality of cell movement was completely reversible upon reversing the field polarity. However, the full reversal of cell direction after the change of EF polarity was much faster in the case of BC (10 minutes) than LC cells (30 minutes). We also investigated the distinct requirements for Rac, Cdc42 and Rho pathways and intracellular Ca2+ in electrotaxis of WC256 sublines forming different types of cell protrusions. It was found that Rac1 is required for directional movement of LC to a much greater extent than for BC, but Cdc42 and RhoA are more crucial for BC than for LC cells. The inhibition of ROCK did not affect electrotaxis of LC in contrast to BC cells. The results also showed that intracellular Ca2+ is essential only for the electrotactic reaction of BC cells. Moreover, inhibition of MLCK and myosin II did not affect the electrotaxis of LC in contrast to BC cells. In conclusion, our results revealed that both lamellipodia and membrane blebs can efficiently drive electrotactic migration of WC 256 carcinosarcoma cells, however directional migration is mediated by different signalling pathways.

  2. Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam.

    PubMed

    Botelho, Nara Macedo; Corrêa, Suelen Costa; Lobato, Rodolfo Costa; Teixeira, Renan Kleber Costa; Quaresma, Juarez Antônio Simões

    2013-03-01

    To investigate the immunohistochemistry of the uterine cervix of 20 Wistar rats (Rattus norvegicus) bearing the Walker 256 tumor, treated with copaiba oil (Copaifera officinalis). The animals were grouped into four subgroups, with five rats each: the GCT and GCopT received distilled water and topically copaiba, respectively, while the GCG and GCopG received distilled water and copaiba by gavage, respectively. The substances were administered for nine days. On the 12th day, after euthanasia, the tumor pieces were sent to the identification of T CD4+, T CD8+ and Natural Killer cells. It was found that the pattern of expression for specific markers of phenotypes of cells involved in tumor immune response was similar in all groups, regardless the administration way of copaiba oil (topical or gavage). Copaiba balsam, administered either topically or by gavage, did not alter the pattern of tumor immune response in rats bearing Walker 256 Tumor.

  3. An SEU resistant 256K SOI SRAM

    NASA Astrophysics Data System (ADS)

    Hite, L. R.; Lu, H.; Houston, T. W.; Hurta, D. S.; Bailey, W. E.

    1992-12-01

    A novel SEU (single event upset) resistant SRAM (static random access memory) cell has been implemented in a 256K SOI (silicon on insulator) SRAM that has attractive performance characteristics over the military temperature range of -55 to +125 C. These include worst-case access time of 40 ns with an active power of only 150 mW at 25 MHz, and a worst-case minimum WRITE pulse width of 20 ns. Measured SEU performance gives an Adams 10 percent worst-case error rate of 3.4 x 10 exp -11 errors/bit-day using the CRUP code with a conservative first-upset LET threshold. Modeling does show that higher bipolar gain than that measured on a sample from the SRAM lot would produce a lower error rate. Measurements show the worst-case supply voltage for SEU to be 5.5 V. Analysis has shown this to be primarily caused by the drain voltage dependence of the beta of the SOI parasitic bipolar transistor. Based on this, SEU experiments with SOI devices should include measurements as a function of supply voltage, rather than the traditional 4.5 V, to determine the worst-case condition.

  4. Respiratory-gated segment reconstruction for radiation treatment planning using 256-slice CT-scanner during free breathing

    NASA Astrophysics Data System (ADS)

    Mori, Shinichiro; Endo, Masahiro; Kohno, Ryosuke; Minohara, Shinichi; Kohno, Kazutoshi; Asakura, Hiroshi; Fujiwara, Hideaki; Murase, Kenya

    2005-04-01

    The conventional respiratory-gated CT scan technique includes anatomic motion induced artifacts due to the low temporal resolution. They are a significant source of error in radiotherapy treatment planning for the thorax and upper abdomen. Temporal resolution and image quality are important factors to minimize planning target volume margin due to the respiratory motion. To achieve high temporal resolution and high signal-to-noise ratio, we developed a respiratory gated segment reconstruction algorithm and adapted it to Feldkamp-Davis-Kress algorithm (FDK) with a 256-detector row CT. The 256-detector row CT could scan approximately 100 mm in the cranio-caudal direction with 0.5 mm slice thickness in one rotation. Data acquisition for the RS-FDK relies on the assistance of the respiratory sensing system by a cine scan mode (table remains stationary). We evaluated RS-FDK in phantom study with the 256-detector row CT and compared it with full scan (FS-FDK) and HS-FDK results with regard to volume accuracy and image noise, and finally adapted the RS-FDK to an animal study. The RS-FDK gave a more accurate volume than the others and it had the same signal-to-noise ratio as the FS-FDK. In the animal study, the RS-FDK visualized the clearest edges of the liver and pulmonary vessels of all the algorithms. In conclusion, the RS-FDK algorithm has a capability of high temporal resolution and high signal-to-noise ratio. Therefore it will be useful when combined with new radiotherapy techniques including image guided radiation therapy (IGRT) and 4D radiation therapy.

  5. Walker 256 Tumor Growth Suppression by Crotoxin Involves Formyl Peptide Receptors and Lipoxin A4

    PubMed Central

    Brigatte, Patrícia; Faiad, Odair Jorge; Ferreira Nocelli, Roberta Cornélio; Landgraf, Richardt G.; Palma, Mario Sergio; Cury, Yara; Curi, Rui; Sampaio, Sandra Coccuzzo

    2016-01-01

    We investigated the effects of Crotoxin (CTX), the main toxin of South American rattlesnake (Crotalus durissus terrificus) venom, on Walker 256 tumor growth, the pain symptoms associated (hyperalgesia and allodynia), and participation of endogenous lipoxin A4. Treatment with CTX (s.c.), daily, for 5 days reduced tumor growth at the 5th day after injection of Walker 256 carcinoma cells into the plantar surface of adult rat hind paw. This observation was associated with inhibition of new blood vessel formation and decrease in blood vessel diameter. The treatment with CTX raised plasma concentrations of lipoxin A4 and its natural analogue 15-epi-LXA4, an effect mediated by formyl peptide receptors (FPRs). In fact, the treatment with Boc-2, an inhibitor of FPRs, abolished the increase in plasma levels of these mediators triggered by CTX. The blockage of these receptors also abolished the inhibitory action of CTX on tumor growth and blood vessel formation and the decrease in blood vessel diameter. Together, the results herein presented demonstrate that CTX increases plasma concentrations of lipoxin A4 and 15-epi-LXA4, which might inhibit both tumor growth and formation of new vessels via FPRs. PMID:27190493

  6. Lamellipodia and Membrane Blebs Drive Efficient Electrotactic Migration of Rat Walker Carcinosarcoma Cells WC 256

    PubMed Central

    Sroka, Jolanta; Krecioch, Izabela; Zimolag, Eliza; Lasota, Slawomir; Rak, Monika; Kedracka-Krok, Sylwia; Borowicz, Pawel; Gajek, Marta; Madeja, Zbigniew

    2016-01-01

    The endogenous electric field (EF) may provide an important signal for directional cell migration during wound healing, embryonic development and cancer metastasis but the mechanism of cell electrotaxis is poorly understood. Additionally, there is no research addressing the question on the difference in electrotactic motility of cells representing various strategies of cell movement—specifically blebbing vs. lamellipodial migration. In the current study we constructed a unique experimental model which allowed for the investigation of electrotactic movement of cells of the same origin but representing different modes of cell migration: weakly adherent, spontaneously blebbing (BC) and lamellipodia forming (LC) WC256 cells. We report that both BC and LC sublines show robust cathodal migration in a physiological EF (1–3 V/cm). The directionality of cell movement was completely reversible upon reversing the field polarity. However, the full reversal of cell direction after the change of EF polarity was much faster in the case of BC (10 minutes) than LC cells (30 minutes). We also investigated the distinct requirements for Rac, Cdc42 and Rho pathways and intracellular Ca2+ in electrotaxis of WC256 sublines forming different types of cell protrusions. It was found that Rac1 is required for directional movement of LC to a much greater extent than for BC, but Cdc42 and RhoA are more crucial for BC than for LC cells. The inhibition of ROCK did not affect electrotaxis of LC in contrast to BC cells. The results also showed that intracellular Ca2+ is essential only for the electrotactic reaction of BC cells. Moreover, inhibition of MLCK and myosin II did not affect the electrotaxis of LC in contrast to BC cells. In conclusion, our results revealed that both lamellipodia and membrane blebs can efficiently drive electrotactic migration of WC 256 carcinosarcoma cells, however directional migration is mediated by different signalling pathways. PMID:26863616

  7. 30 CFR 256.95 - How do I transfer a bonus or royalty credit to another person?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I transfer a bonus or royalty credit to... INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Bonus or Royalty Credits for Exchange of Certain Leases Offshore Florida § 256.95 How do I transfer a bonus or royalty credit...

  8. First Results from HF (High-Frequency) Oblique Backscatter Soundings to the Northwest of College, Alaska Using a Modified ULCAR Digisonde D-256

    DTIC Science & Technology

    1989-03-01

    the D-256: The D-256 vertical sounder has been described in considerable detail by Bibl et al. (1981), but for the sake of completeness, the essential...in Figure 12. 20 Table 3 Status Table for Current Sounder Modes at Sheep Creek 1 VI Z T H X D 7 1 4 (for actual Doppler values, see Table 5.7 in Bibl ...etal, 1981) Azimuth Sequence Code Table 5.9 I oblique ( Bibl ) N P X S U F L V choes have ’EofN 00 3000 2400 1800 1200 600 X 0 polariza ion and Status

  9. A 1 GHz sample rate, 256-channel, 1-bit quantization, CMOS, digital correlator chip

    NASA Technical Reports Server (NTRS)

    Timoc, C.; Tran, T.; Wongso, J.

    1992-01-01

    This paper describes the development of a digital correlator chip with the following features: 1 Giga-sample/second; 256 channels; 1-bit quantization; 32-bit counters providing up to 4 seconds integration time at 1 GHz; and very low power dissipation per channel. The improvements in the performance-to-cost ratio of the digital correlator chip are achieved with a combination of systolic architecture, novel pipelined differential logic circuits, and standard 1.0 micron CMOS process.

  10. ULA-OP 256: A 256-Channel Open Scanner for Development and Real-Time Implementation of New Ultrasound Methods.

    PubMed

    Boni, Enrico; Bassi, Luca; Dallai, Alessandro; Guidi, Francesco; Meacci, Valentino; Ramalli, Alessandro; Ricci, Stefano; Tortoli, Piero

    2016-10-01

    Open scanners offer an increasing support to the ultrasound researchers who are involved in the experimental test of novel methods. Each system presents specific performance in terms of number of channels, flexibility, processing power, data storage capability, and overall dimensions. This paper reports the design criteria and hardware/software implementation details of a new 256-channel ultrasound advanced open platform. This system is organized in a modular architecture, including multiple front-end boards, interconnected by a high-speed (80 Gb/s) ring, capable of finely controlling all transmit (TX) and receive (RX) signals. High flexibility and processing power (equivalent to 2500 GFLOP) are guaranteed by the possibility of individually programming multiple digital signal processors and field programmable gate arrays. Eighty GB of on-board memory are available for the storage of prebeamforming, postbeamforming, and baseband data. The use of latest generation devices allowed to integrate all needed electronics in a small size ( 34 cm ×30 cm ×26 cm). The system implements a multiline beamformer that allows obtaining images of 96 lines by 2048 depths at a frame rate of 720 Hz (expandable to 3000 Hz). The multiline beamforming capability is also exploited to implement a real-time vector Doppler scheme in which a single TX and two independent RX apertures are simultaneously used to maintain the analysis over a full pulse repetition frequency range.

  11. Reduction of the estimated radiation dose and associated patient risk with prospective ECG-gated 256-slice CT coronary angiography

    NASA Astrophysics Data System (ADS)

    Efstathopoulos, E. P.; Kelekis, N. L.; Pantos, I.; Brountzos, E.; Argentos, S.; Grebáč, J.; Ziaka, D.; Katritsis, D. G.; Seimenis, I.

    2009-09-01

    Computed tomography (CT) coronary angiography has been widely used since the introduction of 64-slice scanners and dual-source CT technology, but high radiation doses have been reported. Prospective ECG-gating using a 'step-and-shoot' axial scanning protocol has been shown to reduce radiation exposure effectively while maintaining diagnostic accuracy. 256-slice scanners with 80 mm detector coverage have been currently introduced into practice, but their impact on radiation exposure has not been adequately studied. The aim of this study was to assess radiation doses associated with CT coronary angiography using a 256-slice CT scanner. Radiation doses were estimated for 25 patients scanned with either prospective or retrospective ECG-gating. Image quality was assessed objectively in terms of mean CT attenuation at selected regions of interest on axial coronary images and subjectively by coronary segment quality scoring. It was found that radiation doses associated with prospective ECG-gating were significantly lower than retrospective ECG-gating (3.2 ± 0.6 mSv versus 13.4 ± 2.7 mSv). Consequently, the radiogenic fatal cancer risk for the patient is much lower with prospective gating (0.0176% versus 0.0737%). No statistically significant differences in image quality were observed between the two scanning protocols for both objective and subjective quality assessments. Therefore, prospective ECG-gating using a 'step-and-shoot' protocol that covers the cardiac anatomy in two axial acquisitions effectively reduces radiation doses in 256-slice CT coronary angiography without compromising image quality.

  12. 31 CFR 256.1 - What is Treasury's role in paying awards and settlements from the Judgment Fund?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false What is Treasury's role in paying... Information § 256.1 What is Treasury's role in paying awards and settlements from the Judgment Fund? (a) The... amount exceeds $2,500 (for administrative awards) and is in compliance with the regulatory requirements...

  13. Cervical hip fractures do not occur in arthrotic joints. A clinicoradiographic study of 256 patients.

    PubMed

    Dretakis, E K; Steriopoulos, K A; Kontakis, G M; Giaourakis, G; Economakis, G; Dretakis, K E

    1998-08-01

    We studied endogenic factors for the occurrence of cervical hip fractures in 256 patients. 230 underwent hemiarthroplasty, and 26 were treated with internal fixation or without surgery. The condition of the fractured hip and of the ipsilateral knee, as well as the mobility of the patient before the fracture, were studied in all 256 patients. The removed femoral heads were examined, photographed and radiographs were taken with sensitive film. The acetabulum and the femoral head were macroscopically normal in all 230 cases and there was no radiographic evidence of arthrosis. 64% of the patients were fully mobile before the fracture, 34% were mobile with the aid of a cane and 2% were dependent. In 88%, the ipsilateral knee was normal both clinically and radiographically, and in 12%, there was moderate arthrosis. When comparing the mobility before the fracture and the condition of the ipsilateral hip and knee in 100 patients having a cervical fracture with 100 patients having a trochanteric fracture matched for age and sex, we found that a normal hip joint was sine qua non while a normal ipsilateral knee and a fully mobile individual were important additional conditions for the occurrence of a cervical hip fracture, instead of a trochanteric one, after a fall in an elderly person.

  14. Collagen-coated cellulose sponge: three dimensional matrix for tissue culture of Walker tumor 256.

    PubMed

    Leighton, J; Justh, G; Esper, M; Kronenthal, R L

    1967-03-10

    Three-dimensional growth of large populations of cells in vitro has been observed in the interstices of a matrix consisting of collagen-coated cellu lose sponge. The growth of Walker tumor 256 in this composite matrix is com pared with that found in a matrix composed of either cellulose sponge alone or collagen sponge alone. The composite matrix is superior to either one. Collagen coated cellulose sponge may provide a simple tool for the study of social interaction of cells in the formation of organized elementary tissue structures.

  15. Creatine supplementation prevents hyperhomocysteinemia, oxidative stress and cancer-induced cachexia progression in Walker-256 tumor-bearing rats.

    PubMed

    Deminice, Rafael; Cella, Paola Sanches; Padilha, Camila S; Borges, Fernando H; da Silva, Lilian Eslaine Costa Mendes; Campos-Ferraz, Patrícia L; Jordao, Alceu Afonso; Robinson, Jason Lorne; Bertolo, Robert F; Cecchini, Rubens; Guarnier, Flávia Alessandra

    2016-08-01

    The purpose of this study was to investigate (1) the impact of tumor growth on homocysteine (Hcy) metabolism, liver oxidative stress and cancer cachexia and, (2) the potential benefits of creatine supplementation in Walker-256 tumor-bearing rats. Three experiments were conducted. First, rats were killed on days 5 (D5), 10 (D10) and 14 (D14) after tumor implantation. In experiment 2, rats were randomly assigned to three groups designated as control (C), tumor-bearing (T) and tumor-bearing supplemented with creatine (TCr). A life span experiment was conducted as the third experiment. Creatine was supplied in drinking water for 21 days (8 g/L) in all cases. Tumor implantation consisted of a suspension of Walker-256 cells (8.0 × 10(7) cells in 0.5 mL of PBS). The progressive increase (P < 0.05) in tumor mass coincided with a progressively lower body weight and higher hepatic oxidative stress; plasma Hcy concentration was 80 % higher (P < 0.05) by 10 days of tumor implantation. Impaired Hcy metabolism was evidenced by decreased hepatic betaine-homocysteine methyltransferase (Bhmt), glycine N-methyltransferase (Gnmt) and cystathionine beta synthase (CBS) gene expression. In contrast, creatine supplementation promoted a 28 % reduction of tumor weight (P < 0.05). Plasma Hcy (C 6.1 ± 0.6, T 10.3 ± 1.5, TCr 6.3 ± 0.9, µmol/L) and hepatic oxidative stress were lower in the TCr group compared to T. Creatine supplementation was unable to decrease Hcy concentration and to increase SAM/SAH ratio in tumor tissue. These data suggest that creatine effects on hepatic impaired Hcy metabolism promoted by tumor cell inoculation are responsible to decrease plasma Hcy in tumor-bearing rats. In conclusion, Walker-256 tumor growth is associated with progressive hyperhomocysteinemia, body weight loss and liver oxidative stress in rats. Creatine supplementation, however, prevented these tumor-associated perturbations.

  16. Complete Circular Genome Sequence of Successful ST8/SCCmecIV Community-Associated Methicillin-Resistant Staphylococcus aureus (OC8) in Russia: One-Megabase Genomic Inversion, IS256's Spread, and Evolution of Russia ST8-IV.

    PubMed

    Wan, Tsai-Wen; Khokhlova, Olga E; Iwao, Yasuhisa; Higuchi, Wataru; Hung, Wei-Chun; Reva, Ivan V; Singur, Olga A; Gostev, Vladimir V; Sidorenko, Sergey V; Peryanova, Olga V; Salmina, Alla B; Reva, Galina V; Teng, Lee-Jene; Yamamoto, Tatsuo

    2016-01-01

    ST8/SCCmecIV community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has been a common threat, with large USA300 epidemics in the United States. The global geographical structure of ST8/SCCmecIV has not yet been fully elucidated. We herein determined the complete circular genome sequence of ST8/SCCmecIVc strain OC8 from Siberian Russia. We found that 36.0% of the genome was inverted relative to USA300. Two IS256, oppositely oriented, at IS256-enriched hot spots were implicated with the one-megabase genomic inversion (MbIN) and vSaβ split. The behavior of IS256 was flexible: its insertion site (att) sequences on the genome and junction sequences of extrachromosomal circular DNA were all divergent, albeit with fixed sizes. A similar multi-IS256 system was detected, even in prevalent ST239 healthcare-associated MRSA in Russia, suggesting IS256's strong transmission potential and advantage in evolution. Regarding epidemiology, all ST8/SCCmecIVc strains from European, Siberian, and Far Eastern Russia, examined had MbIN, and geographical expansion accompanied divergent spa types and resistance to fluoroquinolones, chloramphenicol, and often rifampicin. Russia ST8/SCCmecIVc has been associated with life-threatening infections such as pneumonia and sepsis in both community and hospital settings. Regarding virulence, the OC8 genome carried a series of toxin and immune evasion genes, a truncated giant surface protein gene, and IS256 insertion adjacent to a pan-regulatory gene. These results suggest that unique single ST8/spa1(t008)/SCCmecIVc CA-MRSA (clade, Russia ST8-IVc) emerged in Russia, and this was followed by large geographical expansion, with MbIN as an epidemiological marker, and fluoroquinolone resistance, multiple virulence factors, and possibly a multi-IS256 system as selective advantages.

  17. CT Angiography of Peripheral Arterial Disease by 256-Slice Scanner: Accuracy, Advantages and Disadvantages Compared to Digital Subtraction Angiography.

    PubMed

    Mishra, Atul; Jain, Narendra; Bhagwat, Anand

    2017-07-01

    Peripheral arterial occlusive disease (PAOD) may cause disabling claudication or critical limb ischemia. Multidetector computed tomography (CT) technology has evolved to the level of 256-slice CT scanners which has significantly improved the spatial and temporal resolution of the images. This has provided the capability of chasing the contrast bolus at a fast speed enabling angiographic imaging of long segments of the body. These images can be reconstructed in various planes and various modes for detailed analysis of the peripheral vascular diseases which helps in making treatment decision. The aim of this retrospective study was to compare the CT angiograms (CTAs) of all cases of PAOD done by 256-slice CT scanner at a tertiary care vascular center and comparing these images with the digital subtraction angiograms (DSAs) of these patients. The retrospective study included 53 patients who underwent both CTA and DSA at our center over a period of 3 years from March 2013 to March 2016. The CTA showed high sensitivity (93%) and specificity (92.7%) for overall assessment of degree of stenosis in a vascular segment in cases of aortic and lower limb occlusive disease. The assessment of lesions of infrapopliteal segment was comparatively inferior (sensitivity 91.6%, accuracy 73.3%, and positive predictive value 78.5%), more so in the presence of significant calcification. The advantages of CTA were its noninvasive nature, ability to image large area of body, almost no adverse effects to the patients, and better assessment of vessel wall disease. However, the CTA assessment of collaterals was inferior with a sensitivity of only 62.7% as compared to DSA. Overall, 256-slice CTA provides fast and accurate imaging of vascular tree which can restrict DSA only in few selected cases as a problem-solving tool where clinico-radiological mismatch is present.

  18. Structural Variations of Human Glucokinase Glu256Lys in MODY2 Condition Using Molecular Dynamics Study.

    PubMed

    Yellapu, Nanda Kumar; Kandlapalli, Kalpana; Valasani, Koteswara Rao; Sarma, P V G K; Matcha, Bhaskar

    2013-01-01

    Glucokinase (GK) is the predominant hexokinase that acts as glucose sensor and catalyses the formation of Glucose-6-phosphate. The mutations in GK gene influence the affinity for glucose and lead to altered glucose levels in blood causing maturity onset diabetes of the young type 2 (MODY2) condition, which is one of the prominent reasons of type 2 diabetic condition. In view of the importance of mutated GK resulting in hyperglycemic condition, in the present study, molecular dynamics simulations were carried out in intact and 256 E-K mutated GK structures and their energy values and conformational variations were correlated. Energy variations were observed in mutated GK (3500 Kcal/mol) structure with respect to intact GK (5000 Kcal/mol), and it showed increased γ -turns, decreased β -turns, and more helix-helix interactions that affected substrate binding region where its volume increased from 1089.152 Å(2) to 1246.353 Å(2). Molecular docking study revealed variation in docking scores (intact = -12.199 and mutated = -8.383) and binding mode of glucose in the active site of mutated GK where the involvement of A53, S54, K56, K256, D262 and Q286 has resulted in poor glucose binding which probably explains the loss of catalytic activity and the consequent prevailing of high glucose levels in MODY2 condition.

  19. Complete Circular Genome Sequence of Successful ST8/SCCmecIV Community-Associated Methicillin-Resistant Staphylococcus aureus (OC8) in Russia: One-Megabase Genomic Inversion, IS256’s Spread, and Evolution of Russia ST8-IV

    PubMed Central

    Wan, Tsai-Wen; Higuchi, Wataru; Hung, Wei-Chun; Reva, Ivan V.; Singur, Olga A.; Gostev, Vladimir V.; Sidorenko, Sergey V.; Peryanova, Olga V.; Salmina, Alla B.; Reva, Galina V.; Teng, Lee-Jene; Yamamoto, Tatsuo

    2016-01-01

    ST8/SCCmecIV community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has been a common threat, with large USA300 epidemics in the United States. The global geographical structure of ST8/SCCmecIV has not yet been fully elucidated. We herein determined the complete circular genome sequence of ST8/SCCmecIVc strain OC8 from Siberian Russia. We found that 36.0% of the genome was inverted relative to USA300. Two IS256, oppositely oriented, at IS256-enriched hot spots were implicated with the one-megabase genomic inversion (MbIN) and vSaβ split. The behavior of IS256 was flexible: its insertion site (att) sequences on the genome and junction sequences of extrachromosomal circular DNA were all divergent, albeit with fixed sizes. A similar multi-IS256 system was detected, even in prevalent ST239 healthcare-associated MRSA in Russia, suggesting IS256’s strong transmission potential and advantage in evolution. Regarding epidemiology, all ST8/SCCmecIVc strains from European, Siberian, and Far Eastern Russia, examined had MbIN, and geographical expansion accompanied divergent spa types and resistance to fluoroquinolones, chloramphenicol, and often rifampicin. Russia ST8/SCCmecIVc has been associated with life-threatening infections such as pneumonia and sepsis in both community and hospital settings. Regarding virulence, the OC8 genome carried a series of toxin and immune evasion genes, a truncated giant surface protein gene, and IS256 insertion adjacent to a pan-regulatory gene. These results suggest that unique single ST8/spa1(t008)/SCCmecIVc CA-MRSA (clade, Russia ST8-IVc) emerged in Russia, and this was followed by large geographical expansion, with MbIN as an epidemiological marker, and fluoroquinolone resistance, multiple virulence factors, and possibly a multi-IS256 system as selective advantages. PMID:27741255

  20. 25 CFR 256.11 - What are the occupancy and square footage standards for a dwelling provided with Category C...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false What are the occupancy and square footage standards for a..., DEPARTMENT OF THE INTERIOR HOUSING HOUSING IMPROVEMENT PROGRAM § 256.11 What are the occupancy and square... bedrooms Total dwelling square footage 1 (maximum) 1-3 2 2 900 4-6 2 3 1050 7 or more 2 4 31350 1 Total...

  1. 25 CFR 256.11 - What are the occupancy and square footage standards for a dwelling provided with Category C...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What are the occupancy and square footage standards for a..., DEPARTMENT OF THE INTERIOR HOUSING HOUSING IMPROVEMENT PROGRAM § 256.11 What are the occupancy and square... bedrooms Total dwelling square footage 1 (maximum) 1-3 2 2 900 4-6 2 3 1050 7 or more 2 4 31350 1 Total...

  2. 25 CFR 256.11 - What are the occupancy and square footage standards for a dwelling provided with Category C...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What are the occupancy and square footage standards for a..., DEPARTMENT OF THE INTERIOR HOUSING HOUSING IMPROVEMENT PROGRAM § 256.11 What are the occupancy and square... bedrooms Total dwelling square footage 1 (maximum) 1-3 2 2 900 4-6 2 3 1050 7 or more 2 4 31350 1 Total...

  3. 25 CFR 256.11 - What are the occupancy and square footage standards for a dwelling provided with Category C...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false What are the occupancy and square footage standards for a..., DEPARTMENT OF THE INTERIOR HOUSING HOUSING IMPROVEMENT PROGRAM § 256.11 What are the occupancy and square... bedrooms Total dwelling square footage 1 (maximum) 1-3 2 2 900 4-6 2 3 1050 7 or more 2 4 31350 1 Total...

  4. 25 CFR 256.11 - What are the occupancy and square footage standards for a dwelling provided with Category C...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true What are the occupancy and square footage standards for a..., DEPARTMENT OF THE INTERIOR HOUSING HOUSING IMPROVEMENT PROGRAM § 256.11 What are the occupancy and square... bedrooms Total dwelling square footage 1 (maximum) 1-3 2 2 900 4-6 2 3 1050 7 or more 2 4 31350 1 Total...

  5. Structural Variations of Human Glucokinase Glu256Lys in MODY2 Condition Using Molecular Dynamics Study

    PubMed Central

    Yellapu, Nanda Kumar; Kandlapalli, Kalpana; Valasani, Koteswara Rao; Sarma, P. V. G. K.; Matcha, Bhaskar

    2013-01-01

    Glucokinase (GK) is the predominant hexokinase that acts as glucose sensor and catalyses the formation of Glucose-6-phosphate. The mutations in GK gene influence the affinity for glucose and lead to altered glucose levels in blood causing maturity onset diabetes of the young type 2 (MODY2) condition, which is one of the prominent reasons of type 2 diabetic condition. In view of the importance of mutated GK resulting in hyperglycemic condition, in the present study, molecular dynamics simulations were carried out in intact and 256 E-K mutated GK structures and their energy values and conformational variations were correlated. Energy variations were observed in mutated GK (3500 Kcal/mol) structure with respect to intact GK (5000 Kcal/mol), and it showed increased γ-turns, decreased β-turns, and more helix-helix interactions that affected substrate binding region where its volume increased from 1089.152 Å2 to 1246.353 Å2. Molecular docking study revealed variation in docking scores (intact = −12.199 and mutated = −8.383) and binding mode of glucose in the active site of mutated GK where the involvement of A53, S54, K56, K256, D262 and Q286 has resulted in poor glucose binding which probably explains the loss of catalytic activity and the consequent prevailing of high glucose levels in MODY2 condition. PMID:23476789

  6. Leucine-rich diet alters the 1H-NMR based metabolomic profile without changing the Walker-256 tumour mass in rats.

    PubMed

    Viana, Laís Rosa; Canevarolo, Rafael; Luiz, Anna Caroline Perina; Soares, Raquel Frias; Lubaczeuski, Camila; Zeri, Ana Carolina de Mattos; Gomes-Marcondes, Maria Cristina Cintra

    2016-10-03

    Cachexia is one of the most important causes of cancer-related death. Supplementation with branched-chain amino acids, particularly leucine, has been used to minimise loss of muscle tissue, although few studies have examined the effect of this type of nutritional supplementation on the metabolism of the tumour-bearing host. Therefore, the present study evaluated whether a leucine-rich diet affects metabolomic derangements in serum and tumour tissues in tumour-bearing Walker-256 rats (providing an experimental model of cachexia). After 21 days feeding Wistar female rats a leucine-rich diet, distributed in L-leucine and LW-leucine Walker-256 tumour-bearing groups, we examined the metabolomic profile of serum and tumour tissue samples and compared them with samples from tumour-bearing rats fed a normal protein diet (C - control; W - tumour-bearing groups). We utilised 1 H-NMR as a means to study the serum and tumour metabolomic profile, tumour proliferation and tumour protein synthesis pathway. Among the 58 serum metabolites examined, we found that 12 were altered in the tumour-bearing group, reflecting an increase in activity of some metabolic pathways related to energy production, which diverted many nutrients toward tumour growth. Despite displaying increased tumour cell activity (i.e., higher Ki-67 and mTOR expression), there were no differences in tumour mass associated with changes in 23 metabolites (resulting from valine, leucine and isoleucine synthesis and degradation, and from the synthesis and degradation of ketone bodies) in the leucine-tumour group. This result suggests that the majority of nutrients were used for host maintenance. A leucine rich-diet, largely used to prevent skeletal muscle loss, did not affect Walker 256 tumour growth and led to metabolomic alterations that may partially explain the positive effects of leucine for the whole tumour-bearing host.

  7. Follow-up of coronary artery bypass graft patency: diagnostic efficiency of high-pitch dual-source 256-slice MDCT findings.

    PubMed

    Yuceler, Zeyneb; Kantarci, Mecit; Yuce, Ihsan; Kizrak, Yesim; Bayraktutan, Ummugulsum; Ogul, Hayri; Kiris, Adem; Celik, Omer; Pirimoglu, Berhan; Genc, Berhan; Gundogdu, Fuat

    2014-01-01

    Our aim was to evaluate the diagnostic accuracy of 256-slice, high-pitch mode multidetector computed tomography (MDCT) for coronary artery bypass graft (CABG) patency. Eighty-eight patients underwent 256-slice MDCT angiography to evaluate their graft patency after CABG surgery using a prospectively synchronized electrocardiogram in the high-pitch spiral acquisition mode. Effective radiation doses were calculated. We investigated the diagnostic accuracy of high-pitch, low-dose, prospective, electrocardiogram-triggering, dual-source MDCT for CABG patency compared with catheter coronary angiography imaging findings. A total of 215 grafts and 645 vessel segments were analyzed. All graft segments had diagnostic image quality. The proximal and middle graft segments had significantly (P < 0.05) better mean image quality scores (1.18 ± 0.4) than the distal segments (1.31 ± 0.5). Using catheter coronary angiography as the reference standard, high-pitch MDCT had the following sensitivity, specificity, positive predictive value, and negative predictive value of per-segment analysis for detecting graft patency: 97.1%, 99.6%, 94.4%, and 99.8%, respectively. In conclusion, MDCT can be used noninvasively with a lower radiation dose for the assessment of restenosis in CABG patients.

  8. APOA2 -256T>C polymorphism interacts with saturated fatty acids intake to affect anthropometric and hormonal variables in type 2 diabetic patients.

    PubMed

    Basiri, Marjan Ghane; Sotoudeh, Gity; Alvandi, Ehsan; Djalali, Mahmood; Eshraghian, Mohammad Reza; Noorshahi, Neda; Koohdani, Fariba

    2015-05-01

    Recent studies have established the interaction between APOA2 -256T>C polymorphism and dietary saturated fatty acids intake in relation to obesity on healthy individuals. In the current study, we investigate the effects of this interaction on anthropometric variables and serum levels of leptin and ghrelin in patients with type 2 diabetes. In this cross-sectional study, 737 patients with type 2 diabetes mellitus (290 males and 447 females) were recruited from diabetes clinics in Tehran. The usual dietary intake of all participants during the last year was obtained by validated semiquantitative food frequency questionnaire. APOA2 genotyping was performed by real-time PCR on genomic DNA. No significant relation was obtained by univariate analysis between anthropometric variables and APOA2 genotypes. However, after adjusting for age, gender, physical activity and total energy intake, we identified a significant interaction between APOA2-saturated fatty acids intake and body mass index (BMI). After adjusting for potential confounders, serum levels of ghrelin in CC genotype patients were significantly higher than T allele carriers (p = 0.03), whereas the case with leptin did not reveal a significant difference. The result of this study confirmed the interaction between APOA2 -256T>C polymorphism and SFAs intake with BMI in type 2 diabetic patients. In fact, homozygous patients for the C allele with high saturated fatty acids intake had higher BMI. The APOA2 -256T>C polymorphism was associated with elevated levels of serum ghrelin.

  9. A 256 pixel magnetoresistive biosensor microarray in 0.18μm CMOS

    PubMed Central

    Hall, Drew A.; Gaster, Richard S.; Makinwa, Kofi; Wang, Shan X.; Murmann, Boris

    2014-01-01

    Magnetic nanotechnologies have shown significant potential in several areas of nanomedicine such as imaging, therapeutics, and early disease detection. Giant magnetoresistive spin-valve (GMR SV) sensors coupled with magnetic nanotags (MNTs) possess great promise as ultra-sensitive biosensors for diagnostics. We report an integrated sensor interface for an array of 256 GMR SV biosensors designed in 0.18 μm CMOS. Arranged like an imager, each of the 16 column level readout channels contains an analog front- end and a compact ΣΔ modulator (0.054 mm2) with 84 dB of dynamic range and an input referred noise of 49 nT/√Hz. Performance is demonstrated through detection of an ovarian cancer biomarker, secretory leukocyte peptidase inhibitor (SLPI), spiked at concentrations as low as 10 fM. This system is designed as a replacement for optical protein microarrays while also providing real-time kinetics monitoring. PMID:24761029

  10. Radiation dose to patients and image quality evaluation from coronary 256-slice computed tomographic angiography

    NASA Astrophysics Data System (ADS)

    Chen, Liang-Kuang; Wu, Tung-Hsin; Yang, Ching-Ching; Tsai, Chia-Jung; Lee, Jason J. S.

    2010-07-01

    The aim of this study is to assess radiation dose and the corresponding image quality from suggested CT protocols which depends on different mean heart rate and high heart rate variability by using 256-slice CT. Fifty consecutive patients referred for a cardiac CT examination were included in this study. All coronary computed tomographic angiography (CCTA) examinations were performed on a 256-slice CT scanner with one of five different protocols: retrospective ECG-gating (RGH) with full dose exposure in all R-R intervals (protocol A), RGH of 30-80% pulsing window with tube current modulation (B), RGH of 78±5% pulsing window with tube current modulation (C), prospective ECG-triggering (PGT) of 78% R-R interval with 5% padding window (D) and PGT of 78% R-R interval without padding window (E). Radiation dose parameters and image quality scoring were determined and compared. In this study, no significant differences were found in comparison on image quality of the five different protocols. Protocol A obtained the highest radiation dose comparing with those of protocols B, C, D and E by a factor of 1.6, 2.4, 2.5 and 4.3, respectively ( p<0.001), which were ranged between 2.7 and 11.8 mSv. The PGT could significantly reduce radiation dose delivered to patients, as compared to the RGH. However, the use of PGT has limitations and is only good in assessing cases with lower mean heart rate and stable heart rate variability. With higher mean heart rate and high heart rate variability circumstances, the RGH within 30-80% of R-R interval pulsing window is suggested as a feasible technique for assessing diagnostic performance.

  11. 31 CFR 256.32 - What documentation must be submitted to the Judgment Fund Branch to preserve the right to seek...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... to the Judgment Fund Branch to preserve the right to seek interest under 31 U.S.C. 1304(b) in a case... Costs § 256.32 What documentation must be submitted to the Judgment Fund Branch to preserve the right to... preserve interest rights under 31 U.S.C. 1304. A copy of the judgment and cover letter must be sent to the...

  12. Effects of Walker 256 carcinoma on metabolic alterations during the evolution of pregnancy.

    PubMed

    Cintra-Gomes, M C; Cury, L; Parreira, M R; Elias, C F; Areas, M A

    1990-01-01

    The control of pregnant cancer patients is difficult because it involves both mother and fetus, and the metabolic alterations in the cancer host induce a massive mobilization of nutrients diverted to the neoplastic cells. The purpose of the present study was to determine the evolution of the Walker 256 carcinoma in pregnant rats and its consequences on fetal development. The results showed that the tumors displayed a very rapid rate of growth and induced a reduction in fetal weights in the pregnant tumor-bearing rats. The tumor-bearing and pregnant tumor-bearing groups showed a decrease in blood glucose and total serum protein, suggesting an increase in energy utilization of these substrates and synthetic activity by the tumoral cells. An imbalance between protein synthesis and catabolism may occur in the tumor-bearing rats which may be related to the degree of nutritional depletion.

  13. Evaluation of radiation dose of triple rule-out coronary angiography protocols with different scan length using 256-slice CT

    NASA Astrophysics Data System (ADS)

    Tsai, Chia-Jung; Lee, Jason J. S.; Chen, Liang-Kuang; Mok, Greta S. P.; Hsu, Shih-Ming; Wu, Tung-Hsin

    2011-10-01

    Triple rule-out coronary CT angiography (TRO-CTA) is a new approach for providing noninvasive visualization of coronary arteries with simultaneous evaluation of pulmonary arteries, thoracic aorta and other intrathoracic structures. The increasing use of TRO-CTA examination with longer scan length is associated with the concerns about radiation dose and their corresponding cancer risk. The purpose of this study is to evaluate organ dose and effective dose for the TRO-CTA examination with 2 scan lengths: TRO std and TRO ext, using 256-slice CT. TRO-CTA examinations were performed on a 256-slice CT scanner without ECG-based tube current modulation. Absorbed organ doses were measured using an anthropomorphic phantom and thermal-luminance dosimeters (TLDs). Effective dose was determined by taking a sum of the measured absorbed organ doses multiplied with the tissue weighting factor based on ICRP-103, and compared to that calculated using the dose-length product (DLP) method. We obtained high organ doses in the thyroid, esophagus, breast, heart and lung in both TRO-CTA protocols. Effective doses of the TRO std and TRO ext protocols with the phantom method were 26.37 and 42.49 mSv, while those with the DLP method were 19.68 and 38.96 mSv, respectively. Our quantitative dose information establishes a relationship between radiation dose and scanning length, and can provide a practical guidance to best clinical practice.

  14. 256 fs, 2 nJ soliton pulse generation from MoS2 mode-locked fiber laser

    NASA Astrophysics Data System (ADS)

    Jiang, Zike; Chen, Hao; Li, Jiarong; Yin, Jinde; Wang, Jinzhang; Yan, Peiguang

    2017-12-01

    We demonstrate an Er-doped fiber laser (EDFL) mode-locked by a MoS2 saturable absorber (SA), delivering a 256 fs, 2 nJ soliton pulse at 1563.4 nm. The nonlinear property of the SA prepared by magnetron sputtering deposition (MSD) is measured with a modulation depth (MD) of ∼19.48% and a saturable intensity of 4.14 MW/cm2. To the best of our knowledge, the generated soliton pulse has the highest pulse energy of 2 nJ among the reported mode-locked EDFLs based on transition metal dichalcogenides (TMDs). Our results indicate that MSD-grown SAs could offer an exciting platform for high pulse energy and ultrashort pulse generation.

  15. Combination of advanced encryption standard 256 bits with md5 to secure documents on android smartphone

    NASA Astrophysics Data System (ADS)

    Pasaribu, Hendra; Sitanggang, Delima; Rizki Damanik, Rudolfo; Rudianto Sitompul, Alex Chandra

    2018-04-01

    File transfer by using a smartphone has some security issues like data theft by irresponsible parties. To improve the quality of data security systems on smartphones, in this research the integration of AES 256 bit algorithm by using MD5 hashing is proposed. The use of MD5 aims to increase the key strength of the encryption and decryption process of document files. The test results show that the proposed method can increase the key strength of the encryption and decryption process in the document file. Encryption and decryption time by using AES and MD5 combination is faster than using AES only on *.txt file type and reverse results for *.docx, *.xlsx, *.pptx and *.pdf file files.

  16. Metformin reduces the Walker-256 tumor development in obese-MSG rats via AMPK and FOXO3a.

    PubMed

    de Queiroz, Eveline A I F; Akamine, Eliana H; de Carvalho, Maria Helena C; Sampaio, Sandra C; Fortes, Zuleica B

    2015-01-15

    Studies have associated obesity with a wide variety of cancers. Metformin, an anti-diabetic drug, has recently received attention as a potentially useful therapeutic agent for treating cancer. Therefore, the objective of this study was to analyze the mechanisms involved in the increase in tumor development and the reduction of it by metformin in obesity using an experimental breast tumor model. Newborn male Wistar rats were subcutaneously injected with 400mg/kg monosodium glutamate (MSG) (obese) or saline (control) at 2, 3, 4, 5 and 6 days of age. After 16 weeks, 1 × 10(7) Walker-256 tumor cells were subcutaneously injected in the right flank of the rats and concomitantly the treatment with metformin 300 mg/kg/15 days, via gavage, started. The rats were divided into 4 groups: control tumor (CT), control tumor metformin (CTM), obese-MSG tumor (OT) and obese-MSG tumor metformin (OTM). On the 18th week the tumor development and metformin effect were analyzed. Tumor development was higher in OT rats compared with CT rats. Activation of insulin-IR-ERK1/2 pathway and an anti-apoptotic effect might be the mechanisms involved in the higher development of tumor in obesity. The effect of metformin reducing the tumor development in obese rats might involve increased mRNA expression of pRb and p27, increased activity of AMPK and FOXO3a and decreased expression of p-ERK1/2 (Thr202/Tyr204) in Walker-256 tumor. Our data allow us to suggest that metformin, reducing the stimulatory effect of obesity on tumor development, has a potential role in the management of cancers. Copyright © 2014 Elsevier Inc. All rights reserved.

  17. Spatial mapping and statistical reproducibility of an array of 256 one-dimensional quantum wires

    NASA Astrophysics Data System (ADS)

    Al-Taie, H.; Smith, L. W.; Lesage, A. A. J.; See, P.; Griffiths, J. P.; Beere, H. E.; Jones, G. A. C.; Ritchie, D. A.; Kelly, M. J.; Smith, C. G.

    2015-08-01

    We utilize a multiplexing architecture to measure the conductance properties of an array of 256 split gates. We investigate the reproducibility of the pinch off and one-dimensional definition voltage as a function of spatial location on two different cooldowns, and after illuminating the device. The reproducibility of both these properties on the two cooldowns is high, the result of the density of the two-dimensional electron gas returning to a similar state after thermal cycling. The spatial variation of the pinch-off voltage reduces after illumination; however, the variation of the one-dimensional definition voltage increases due to an anomalous feature in the center of the array. A technique which quantifies the homogeneity of split-gate properties across the array is developed which captures the experimentally observed trends. In addition, the one-dimensional definition voltage is used to probe the density of the wafer at each split gate in the array on a micron scale using a capacitive model.

  18. High-port low-latency optical switch architecture with optical feed-forward buffering for 256-node disaggregated data centers.

    PubMed

    Terzenidis, Nikos; Moralis-Pegios, Miltiadis; Mourgias-Alexandris, George; Vyrsokinos, Konstantinos; Pleros, Nikos

    2018-04-02

    Departing from traditional server-centric data center architectures towards disaggregated systems that can offer increased resource utilization at reduced cost and energy envelopes, the use of high-port switching with highly stringent latency and bandwidth requirements becomes a necessity. We present an optical switch architecture exploiting a hybrid broadcast-and-select/wavelength routing scheme with small-scale optical feedforward buffering. The architecture is experimentally demonstrated at 10Gb/s, reporting error-free performance with a power penalty of <2.5dB. Moreover, network simulations for a 256-node system, revealed low-latency values of only 605nsec, at throughput values reaching 80% when employing 2-packet-size optical buffers, while multi-rack network performance was also investigated.

  19. Childhood history of behavioral inhibition and comorbidity status in 256 adults with social phobia.

    PubMed

    Rotge, Jean-Yves; Grabot, Denis; Aouizerate, Bruno; Pélissolo, Antoine; Lépine, Jean-Pierre; Tignol, Jean

    2011-03-01

    Behavioral inhibition (BI), a heritable temperament, predisposes one to an increased risk of social phobia. Recent investigations have reported that BI may also be a precursor to anxiety as well as depressive and alcohol-related disorders, which are frequently comorbid with social phobia. In the present study, we explored the relationship between BI and psychiatric disorders in 256 adults with a primary diagnosis of social phobia. BI severity was retrospectively assessed with the Retrospective Self-Report of Inhibition (RSRI). The severity of social phobia and the presence of comorbid diagnoses were evaluated with the Liebowitz Social Anxiety Scale (LSAS) and the Mini-International Neuropsychiatric Interview, respectively. The RSRI score was significantly and positively correlated with both the LSAS score and the occurrence of a major depressive disorder. No significant association was found with other anxiety and substance-related disorders. The assessment of BI was retrospective and self-reported. A childhood history of BI was associated with an increased risk of depressive comorbidity in social phobia. Copyright © 2010 Elsevier B.V. All rights reserved.

  20. Systematization of actinides using cluster analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kopyrin, A.A.; Terent`eva, T.N.; Khramov, N.N.

    1994-11-01

    A representation of the actinides in multidimensional property space is proposed for systematization of these elements using cluster analysis. Literature data for their atomic properties are used. Owing to the wide variation of published ionization potentials, medians are used to estimate them. Vertical dendograms are used for classification on the basis of distances between the actinides in atomic-property space. The properties of actinium and lawrencium are furthest removed from the main group. Thorium and mendelevium exhibit individualized properties. A cluster based on the einsteinium-fermium pair is joined by californium.

  1. Resistance exercise attenuates skeletal muscle oxidative stress, systemic pro-inflammatory state, and cachexia in Walker-256 tumor-bearing rats.

    PubMed

    Padilha, Camila Souza; Borges, Fernando Henrique; Costa Mendes da Silva, Lilian Eslaine; Frajacomo, Fernando Tadeu Trevisan; Jordao, Alceu Afonso; Duarte, José Alberto; Cecchini, Rubens; Guarnier, Flávia Alessandra; Deminice, Rafael

    2017-09-01

    The aim of this study was to investigate the effects of resistance exercise training (RET) on oxidative stress, systemic inflammatory markers, and muscle wasting in Walker-256 tumor-bearing rats. Male (Wistar) rats were divided into 4 groups: sedentary controls (n = 9), tumor-bearing (n = 9), exercised (n = 9), and tumor-bearing exercised (n = 10). Exercised and tumor-bearing exercised rats were exposed to resistance exercise of climbing a ladder apparatus with weights tied to their tails for 6 weeks. The physical activity of control and tumor-bearing rats was confined to the space of the cage. After this period, tumor-bearing and tumor-bearing exercised animals were inoculated subcutaneously with Walker-256 tumor cells (11.0 × 10 7 cells in 0.5 mL of phosphate-buffered saline) while control and exercised rats were injected with vehicle. Following inoculation, rats maintained resistance exercise training (exercised and tumor-bearing exercised) or sedentary behavior (control and tumor-bearing) for 12 more days, after which they were euthanized. Results showed muscle wasting in the tumor-bearing group, with body weight loss, increased systemic leukocytes, and inflammatory interleukins as well as muscular oxidative stress and reduced mTOR signaling. In contrast, RET in the tumor-bearing exercised group was able to mitigate the reduced body weight and muscle wasting with the attenuation of muscle oxidative stress and systemic inflammatory markers. RET also prevented loss of muscle strength associated with tumor development. RET, however, did not prevent the muscle proteolysis signaling via FBXO32 gene messenger RNA expression in the tumor-bearing group. In conclusion, RET performed prior tumor implantation prevents cachexia development by attenuating tumor-induced systemic pro-inflammatory condition with muscle oxidative stress and muscle damage.

  2. Morphologic classification of the right auricule on 256-slice computed tomography.

    PubMed

    Li, Cai-Ying; Gao, Bu-Lang; Pan, Tong; Xiang, Cheng; Liu, Xiao-Wei; Yang, Hai-Qing; Yi, Lan-Ying; Liao, Qi-Bin

    2017-06-01

    To investigate the shape of right auricule on 256-slice computed tomography (CT). Five hundred people (250 men, age range 16-84 years) who had cardiac multidetector CT angiography were recruited in this study. All patients had normal sinus rhythm with normal blood pressure (<140/90 mmHg for systolic/diastolic pressure). The morphology of the right auricule was studied and compared after reconstruction of the raw images. All patients successfully had cardiac CT angiography (100%), and the right auricule morphology was divided into five types and nine subtypes, including Type I of triangular shape (Ia and Ib), Type II of M shape (IIa and IIb), Type III of L shape (IIIa and IIIb), Type IV of reverse L shape (IVa and IVb), and Type V of balanced shape. The most common type of right auricule is Type IV (28.4%) followed by Type II (24.0%), whereas the least common is Type V (11.0%). Type Ia was present significantly (P < 0.0001) more frequently in females than in males, whereas Type IIa significantly (P = 0.042) more frequently in males than females. No other significant (P > 0.05) sex difference existed in the constitution ratio of the types. The normal angle was greater in Type Ib than in Ia. The greater the normal angle in Type I, the greater the deviation of the right auricule tip towards the left. A good understanding of the right auricule anatomical morphology can better guide atrial pacing, radiofrequency ablation and other surgical procedures while preventing possible intra-procedural complications.

  3. Cryogenic on-chip multiplexer for the study of quantum transport in 256 split-gate devices

    NASA Astrophysics Data System (ADS)

    Al-Taie, H.; Smith, L. W.; Xu, B.; See, P.; Griffiths, J. P.; Beere, H. E.; Jones, G. A. C.; Ritchie, D. A.; Kelly, M. J.; Smith, C. G.

    2013-06-01

    We present a multiplexing scheme for the measurement of large numbers of mesoscopic devices in cryogenic systems. The multiplexer is used to contact an array of 256 split gates on a GaAs/AlGaAs heterostructure, in which each split gate can be measured individually. The low-temperature conductance of split-gate devices is governed by quantum mechanics, leading to the appearance of conductance plateaux at intervals of 2e2/h. A fabrication-limited yield of 94% is achieved for the array, and a "quantum yield" is also defined, to account for disorder affecting the quantum behaviour of the devices. The quantum yield rose from 55% to 86% after illuminating the sample, explained by the corresponding increase in carrier density and mobility of the two-dimensional electron gas. The multiplexer is a scalable architecture, and can be extended to other forms of mesoscopic devices. It overcomes previous limits on the number of devices that can be fabricated on a single chip due to the number of electrical contacts available, without the need to alter existing experimental set ups.

  4. Constraints on Planetary Companions in the Magnification A=256 Microlensing Event OGLE-2003-BLG-423

    NASA Astrophysics Data System (ADS)

    Yoo, Jaiyul; DePoy, D. L.; Gal-Yam, A.; Gaudi, B. S.; Gould, A.; Han, C.; Lipkin, Y.; Maoz, D.; Ofek, E. O.; Park, B.-G.; Pogge, R. W.; Mu Fun Collaboration; Szymański, M. K.; Udalski, A.; Szewczyk, O.; Kubiak, M.; Żebruń, K.; Pietrzyński, G.; Soszyński, I.; Wyrzykowski, Ł.; OGLE Collaboration

    2004-12-01

    We develop a new method of modeling microlensing events based on a Monte Carlo simulation that incorporates both a Galactic model and the constraints imposed by the observed characteristics of the event. The method provides an unbiased way to analyze the event, especially when parameters are poorly constrained by the observed light curve. We apply this method to search for planetary companions of the lens in OGLE-2003-BLG-423, whose maximum magnification Amax=256+/-43 (or Amax=400+/-115 from the light-curve data alone) is the highest among single-lens events ever recorded. The method permits us for the first time to place constraints directly in the planet mass-projected physical separation plane rather than in the mass ratio-Einstein radius plane as was done previously. For example, Jovian-mass companions of main-sequence stars at 2.5 AU are excluded with 80% efficiency. Based in part on observations obtained with the 1.3 m Warsaw Telescope at the Las Campanas Observatory of the Carnegie Institution of Washington.

  5. Design, Synthesis and Evaluation of Novel 2,5,6-Trisubstituted Benzimidazoles Targeting FtsZ as Antitubercular Agents

    PubMed Central

    Park, Bora; Awasthi, Divya; Chowdhury, Soumya R.; Melief, Eduard H.; Kumar, Kunal; Knudson, Susan E.; Slayden, Richard A.; Ojima, Iwao

    2014-01-01

    Filamenting temperature-sensitive protein Z (FtsZ), an essential cell division protein, is a promising target for the drug discovery of new-generation antibacterial agents against various bacterial pathogens. As a part of SAR studies on benzimidazoles, we have synthesized a library of 376 novel 2,5,6-trisubstituted benzimidazoles, bearing ether or thioether linkage at the 6-position. In a preliminary HTP screening against Mtb H37Rv, 108 compounds were identified as hits at a cut off concentration of 5 μg/mL. Among those hits, 10 compounds exhibited MIC values in the range of 0.63–12.5 μg/mL. Light scattering assay and TEM analysis with the most potent compound 5a clearly indicate that its molecular target is Mtb-FtsZ. Also, the Kd of 5a with Mtb-FtsZ was determined to be 1.32 μM. PMID:24726304

  6. Coronary Stent Artifact Reduction with an Edge-Enhancing Reconstruction Kernel - A Prospective Cross-Sectional Study with 256-Slice CT.

    PubMed

    Tan, Stéphanie; Soulez, Gilles; Diez Martinez, Patricia; Larrivée, Sandra; Stevens, Louis-Mathieu; Goussard, Yves; Mansour, Samer; Chartrand-Lefebvre, Carl

    2016-01-01

    Metallic artifacts can result in an artificial thickening of the coronary stent wall which can significantly impair computed tomography (CT) imaging in patients with coronary stents. The objective of this study is to assess in vivo visualization of coronary stent wall and lumen with an edge-enhancing CT reconstruction kernel, as compared to a standard kernel. This is a prospective cross-sectional study involving the assessment of 71 coronary stents (24 patients), with blinded observers. After 256-slice CT angiography, image reconstruction was done with medium-smooth and edge-enhancing kernels. Stent wall thickness was measured with both orthogonal and circumference methods, averaging thickness from diameter and circumference measurements, respectively. Image quality was assessed quantitatively using objective parameters (noise, signal to noise (SNR) and contrast to noise (CNR) ratios), as well as visually using a 5-point Likert scale. Stent wall thickness was decreased with the edge-enhancing kernel in comparison to the standard kernel, either with the orthogonal (0.97 ± 0.02 versus 1.09 ± 0.03 mm, respectively; p<0.001) or the circumference method (1.13 ± 0.02 versus 1.21 ± 0.02 mm, respectively; p = 0.001). The edge-enhancing kernel generated less overestimation from nominal thickness compared to the standard kernel, both with the orthogonal (0.89 ± 0.19 versus 1.00 ± 0.26 mm, respectively; p<0.001) and the circumference (1.06 ± 0.26 versus 1.13 ± 0.31 mm, respectively; p = 0.005) methods. The edge-enhancing kernel was associated with lower SNR and CNR, as well as higher background noise (all p < 0.001), in comparison to the medium-smooth kernel. Stent visual scores were higher with the edge-enhancing kernel (p<0.001). In vivo 256-slice CT assessment of coronary stents shows that the edge-enhancing CT reconstruction kernel generates thinner stent walls, less overestimation from nominal thickness, and better image quality scores than the standard kernel.

  7. Design, synthesis and evaluation of novel 2,5,6-trisubstituted benzimidazoles targeting FtsZ as antitubercular agents.

    PubMed

    Park, Bora; Awasthi, Divya; Chowdhury, Soumya R; Melief, Eduard H; Kumar, Kunal; Knudson, Susan E; Slayden, Richard A; Ojima, Iwao

    2014-05-01

    Filamenting temperature-sensitive protein Z (FtsZ), an essential cell division protein, is a promising target for the drug discovery of new-generation antibacterial agents against various bacterial pathogens. As a part of SAR studies on benzimidazoles, we have synthesized a library of 376 novel 2,5,6-trisubstituted benzimidazoles, bearing ether or thioether linkage at the 6-position. In a preliminary HTP screening against Mtb H37Rv, 108 compounds were identified as hits at a cut off concentration of 5 μg/mL. Among those hits, 10 compounds exhibited MIC values in the range of 0.63-12.5 μg/mL. Light scattering assay and TEM analysis with the most potent compound 5a clearly indicate that its molecular target is Mtb-FtsZ. Also, the Kd of 5a with Mtb-FtsZ was determined to be 1.32 μM. Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. KOI-256's Magnetic Activity Under the Influence of the White Dwarf

    NASA Astrophysics Data System (ADS)

    Yoldaş, Ezgi; Dal, Hasan Ali

    2017-11-01

    We present the findings about chromospheric activity nature of KOI-256 obtained from the Kepler Mission data. First, it was found that there are some sinusoidal variations out-of-eclipses due to cool spot activity. The sinusoidal variations modelled by the spotmodel program indicate that the active component has two different active regions. Their longitudinal variation revealed that one of them has a migration period of 3.95 yrs, while the other has a migration period of 8.37 yrs. Second, 225 flares were detected from the short cadence data in total. The parameters, such as increase (T r) and decay (T d) times, total flare time (T t), equivalent durations (P), were calculated for each flare. The distribution of equivalent durations versus total flare times in logarithmic scale is modelled to find flare activity level. The Plateau value known as the saturation level of the active component was calculated to be 2.3121 ± 0.0964 s, and the Half-life value, which is required flare total time to reach the saturation, was computed to be 2233.6 s. In addition, the frequency of N 1, which is the number of flares per an hour in the system, was found to be 0.05087 h-1, while the flare frequency N 2 that the flare-equivalent duration emitting per an hour was found to be 0.00051. Contrary to the spot activity, it has been found that the flares are in tends to appear at specific phases due to the white dwarf component.

  9. Effects of hyperthermia and hyperglycemia on the metastases formation and on survival of rat bearing W256 carcinosarcoma.

    PubMed

    Shah, S A; Jain, R K; Finney, P L

    1982-01-01

    Hyperthermia (temperatures less than 42 degrees C) is widely used in the treatment of cancer. Current thrust in this field is directed towards using agents which can potentiate the effects of hyperthermia. Combined local hyperthermia (43 degrees C/2 hours) and hyperglycemia (6g glucose/kg body weight; mean blood glucose levels of 500 mg%) was investigated for treating a metastasizing form of a rat W256 carcinosarcoma. Glucose loading of the tumor-bearing rats rendered the foot tumors physically more easy to heat (due to inhibition of tumor blood flow), but combined hyperthermia and hyperglycemia lead to a decrease in survival rate (13% compared to 41% with heat alone), most animals died with widespread metastases in lymph nodes, lungs and kidneys. The data does not support the postulate that hyperglycemia leads to sensitization of tumor destruction by hyperthermia. We suggest that Corynebacterium parvum, a non-specific immunostimulant, should be thoroughly investigated as a potentiator of hyperthermia.

  10. Retarded protein folding of deficient human α1-antitrypsin D256V and L41P variants

    PubMed Central

    Jung, Chan-Hun; Na, Yu-Ran; Im, Hana

    2004-01-01

    α1-Antitrypsin is the most abundant protease inhibitor in plasma and is the archetype of the serine protease inhibitor superfamily. Genetic variants of human α1-antitrypsin are associated with early-onset emphysema and liver cirrhosis. However, the detailed molecular mechanism for the pathogenicity of most variant α1-antitrypsin molecules is not known. Here we examined the structural basis of a dozen deficient α1-antitrypsin variants. Unlike most α1-antitrypsin variants, which were unstable, D256V and L41P variants exhibited extremely retarded protein folding as compared with the wild-type molecule. Once folded, however, the stability and inhibitory activity of these variant proteins were comparable to those of the wild-type molecule. Retarded protein folding may promote protein aggregation by allowing the accumulation of aggregation-prone folding intermediates. Repeated observations of retarded protein folding indicate that it is an important mechanism causing α1-antitrypsin deficiency by variant molecules, which have to fold into the metastable native form to be functional. PMID:14767073

  11. Quantitative analysis of the right auricle with 256-slice computed tomography.

    PubMed

    Li, Cai-Ying; Gao, Bu-Lang; Pan, Tong; Xiang, Cheng; Zhang, Xue-Jing; Liu, Xiao-Wei; Fan, Qiong-Ying

    2017-04-01

    To quantitatively measure the morphology parameters of the right auricle with 256-slice multidetector computed tomography angiography (MDCTA) in healthy people. A retrospective analysis of 200 patients who had undergone coronary MDCTA with negative findings was performed. The raw imaging data were reconstructed and the right auricular volume, right atrial volume, right auricle height, base long and short axes, base perimeter and area, normal angle, and distance were quantitatively measured. Men had significantly (P < 0.05) greater values than women in the right auricular volume (13.3 ± 4.0 vs. 11.7 ± 3.7 mL) and height (33.0 ± 5.0 vs. 30.5 ± 5.2 mm), the base long axis (34.4 ± 4.1 vs. 33.2 ± 3.9 mm), area (787.6 ± 177.6 vs. 771.0 ± 143.2 mm 2 ) and perimeter (119.2 ± 17.5 vs. 115.0 ± 13.0), and the normal distance (22.4 ± 6.6 vs. 20.2 ± 6.7 mm). The normal 95 % reference range for the right auricular parameters was put forward. The right auricular parameters had a good correlation with the right atrium volume, aortic diameter, the body weight, height, and body surface area but a bad correlation with the vertebral body height. Significantly (P < 0.05) greater values were found in the normal angle and distance in subjects below than over 40 years of age. No other significant (P > 0.05) difference existed in the other right auricular parameters. Quantitative measurements of the right auricle can help us get a good understanding of the right auricular morphology and its relationship with surrounding structures and are helpful for cardiac interventions of electrophysiology and radiofrequency ablation.

  12. 320 x 256 Complementary Barrier Infrared Detector Focal Plane Array for Long-Wave Infrared Imaging

    NASA Technical Reports Server (NTRS)

    Nguyen, Jean; Rafol, Sir B.; Soibel, Alexander; Khoskhlagh, Arezou; Ting, David Z.-Y.; Liu, John K.; Mumolo, Jason M.; Gunapala, Sarath D.

    2012-01-01

    A 320 x 256 Complementary Barrier Infrared (CBIRD) focal plane array for long-wavelength infrared (LWIR) imaging is reported. The arrays were grown by molecular beam expitaxy (MBE) with a 300 period 1.9 um thick absorber. The mean dark current density of 2.2 x 10-4 A/cm2 was measured at an operating bias of 128 mV with a long wavelength cutoff of 8.8 ?m observed at 50% of the peak. The maximum quantum efficiency was 54% measured at 5.6 ?m. Operating at T = 80K, the array yielded an 81% fill factor with 97% operability. Good imagery with a mean noise equivalent different temperature (NE?T) of 18.6 mK and a mean detectivity of D* = 1.3 x 1011 cm-Hz1/2/W was achieved. The substrate was thinned using mechanical lapping and neither an AR coating nor a passivation layer was applied. This article provides the details of the fabrication process for achieving low-dark current LWIR CBIRD arrays. Discussion for an effective hard mask for excellent pattern transfer is given and appropriate mounting techniques for good thermal contact during the dry etching process is described. The challenges and differences between etching large 200 ?m test diodes and small 28 ?m FPA pixels are given.

  13. Pixel parallel localized driver design for a 128 x 256 pixel array 3D 1Gfps image sensor

    NASA Astrophysics Data System (ADS)

    Zhang, C.; Dao, V. T. S.; Etoh, T. G.; Charbon, E.

    2017-02-01

    In this paper, a 3D 1Gfps BSI image sensor is proposed, where 128 × 256 pixels are located in the top-tier chip and a 32 × 32 localized driver array in the bottom-tier chip. Pixels are designed with Multiple Collection Gates (MCG), which collects photons selectively with different collection gates being active at intervals of 1ns to achieve 1Gfps. For the drivers, a global PLL is designed, which consists of a ring oscillator with 6-stage current starved differential inverters, achieving a wide frequency tuning range from 40MHz to 360MHz (20ps rms jitter). The drivers are the replicas of the ring oscillator that operates within a PLL. Together with level shifters and XNOR gates, continuous 3.3V pulses are generated with desired pulse width, which is 1/12 of the PLL clock period. The driver array is activated by a START signal, which propagates through a highly balanced clock tree, to activate all the pixels at the same time with virtually negligible skew.

  14. Validation of new superheavy elements and IUPAC-IUPAP joint working group

    NASA Astrophysics Data System (ADS)

    Jarlskog, Cecilia

    2016-12-01

    The great chemist Glenn Seaborg has written a delightful little book "Man-made Transuranium Elements", published in 1963, in which he points out that: "The former basic criterion for the discovery of a new element - namely, chemical identification and separation from all previously-known elements - had to be changed in the case of lawrencium (element 103). This also may be true for elements beyond lawrencium." Indeed this is what has happened. The elements with Z ≥ 103 are produced in nuclear reactions and are detected by counters. The detectors have undergone substantial refinement. For example one uses multiwire proportional chambers [for which George Charpak received the 1992 Nobel Prize in Physics] as well as solid state micro-strip detectors. In spite of this remarkable shift from chemistry to physics, the managerial staff of the International Union of Pure and Applied Chemistry (IUPAC) does not seem to be aware of what has been going on. The validation of superheavy elements should be done by physicists as the chemists lack the relevant competence as I will discuss here below. This article is about a collaboration between International Union of Pure and Applied Chemistry (IUPAC) and its sister organization International Union of Pure and Applied Physics (IUPAP), to deal with discovery of superheavy elements beyond Z = 112. I spent a great deal of time on this issue. In my opinion, the collaboration turned out to be a failure. For the sake of science, which should be our most important concern (and not politics), the rules for the future collaborations, if any, should be accurately defined and respected. The validation of new elements should be done by people who have the relevant competence - the physicists.

  15. A customizable commercial miniaturized 320×256 indium gallium arsenide shortwave infrared camera

    NASA Astrophysics Data System (ADS)

    Huang, Shih-Che; O'Grady, Matthew; Groppe, Joseph V.; Ettenberg, Martin H.; Brubaker, Robert M.

    2004-10-01

    The design and performance of a commercial short-wave-infrared (SWIR) InGaAs microcamera engine is presented. The 0.9-to-1.7 micron SWIR imaging system consists of a room-temperature-TEC-stabilized, 320x256 (25 μm pitch) InGaAs focal plane array (FPA) and a high-performance, highly customizable image-processing set of electronics. The detectivity, D*, of the system is greater than 1013 cm-√Hz/W at 1.55 μm, and this sensitivity may be adjusted in real-time over 100 dB. It features snapshot-mode integration with a minimum exposure time of 130 μs. The digital video processor provides real time pixel-to-pixel, 2-point dark-current subtraction and non-uniformity compensation along with defective-pixel substitution. Other features include automatic gain control (AGC), gamma correction, 7 preset configurations, adjustable exposure time, external triggering, and windowing. The windowing feature is highly flexible; the region of interest (ROI) may be placed anywhere on the imager and can be varied at will. Windowing allows for high-speed readout enabling such applications as target acquisition and tracking; for example, a 32x32 ROI window may be read out at over 3500 frames per second (fps). Output video is provided as EIA170-compatible analog, or as 12-bit CameraLink-compatible digital. All the above features are accomplished in a small volume < 28 cm3, weight < 70 g, and with low power consumption < 1.3 W at room temperature using this new microcamera engine. Video processing is based on a field-programmable gate array (FPGA) platform with a soft-embedded processor that allows for ease of integration/addition of customer-specific algorithms, processes, or design requirements. The camera was developed with the high-performance, space-restricted, power-conscious application in mind, such as robotic or UAV deployment.

  16. A reconfigurable on-line learning spiking neuromorphic processor comprising 256 neurons and 128K synapses

    PubMed Central

    Qiao, Ning; Mostafa, Hesham; Corradi, Federico; Osswald, Marc; Stefanini, Fabio; Sumislawska, Dora; Indiveri, Giacomo

    2015-01-01

    Implementing compact, low-power artificial neural processing systems with real-time on-line learning abilities is still an open challenge. In this paper we present a full-custom mixed-signal VLSI device with neuromorphic learning circuits that emulate the biophysics of real spiking neurons and dynamic synapses for exploring the properties of computational neuroscience models and for building brain-inspired computing systems. The proposed architecture allows the on-chip configuration of a wide range of network connectivities, including recurrent and deep networks, with short-term and long-term plasticity. The device comprises 128 K analog synapse and 256 neuron circuits with biologically plausible dynamics and bi-stable spike-based plasticity mechanisms that endow it with on-line learning abilities. In addition to the analog circuits, the device comprises also asynchronous digital logic circuits for setting different synapse and neuron properties as well as different network configurations. This prototype device, fabricated using a 180 nm 1P6M CMOS process, occupies an area of 51.4 mm2, and consumes approximately 4 mW for typical experiments, for example involving attractor networks. Here we describe the details of the overall architecture and of the individual circuits and present experimental results that showcase its potential. By supporting a wide range of cortical-like computational modules comprising plasticity mechanisms, this device will enable the realization of intelligent autonomous systems with on-line learning capabilities. PMID:25972778

  17. A reconfigurable on-line learning spiking neuromorphic processor comprising 256 neurons and 128K synapses.

    PubMed

    Qiao, Ning; Mostafa, Hesham; Corradi, Federico; Osswald, Marc; Stefanini, Fabio; Sumislawska, Dora; Indiveri, Giacomo

    2015-01-01

    Implementing compact, low-power artificial neural processing systems with real-time on-line learning abilities is still an open challenge. In this paper we present a full-custom mixed-signal VLSI device with neuromorphic learning circuits that emulate the biophysics of real spiking neurons and dynamic synapses for exploring the properties of computational neuroscience models and for building brain-inspired computing systems. The proposed architecture allows the on-chip configuration of a wide range of network connectivities, including recurrent and deep networks, with short-term and long-term plasticity. The device comprises 128 K analog synapse and 256 neuron circuits with biologically plausible dynamics and bi-stable spike-based plasticity mechanisms that endow it with on-line learning abilities. In addition to the analog circuits, the device comprises also asynchronous digital logic circuits for setting different synapse and neuron properties as well as different network configurations. This prototype device, fabricated using a 180 nm 1P6M CMOS process, occupies an area of 51.4 mm(2), and consumes approximately 4 mW for typical experiments, for example involving attractor networks. Here we describe the details of the overall architecture and of the individual circuits and present experimental results that showcase its potential. By supporting a wide range of cortical-like computational modules comprising plasticity mechanisms, this device will enable the realization of intelligent autonomous systems with on-line learning capabilities.

  18. The triaxiality and Coriolis effects on the fission barrier in isovolumic nuclei with mass number A = 256 based on multidimensional total Routhian surface calculations

    NASA Astrophysics Data System (ADS)

    Chai, Qing-Zhen; Zhao, Wei-Juan; Wang, Hua-Lei; Liu, Min-Liang; Xu, Fu-Rong

    2018-05-01

    The triaxiality and Coriolis effects on the first fission barrier in even-even nuclei with A=256 have been studied in terms of the approach of multidimensional total Routhian surface calculations. The present results are compared with available data and other theories, showing a good agreement. Based on the deformation energy or Routhian curves, the first fission barriers are analyzed, focusing on their shapes, heights, and evolution with rotation. It is found that, relative to the effect on the ground-state minimum, the saddle point, at least the first one, can be strongly affected by the triaxial deformation degree of freedom and Coriolis force. The evolution trends of the macroscopic and microscopic (shell and pairing) contributions as well as the triaxial fission barriers are briefly discussed.

  19. Bax/Bcl-2 protein expression ratio and leukocyte function are related to reduction of Walker-256 tumor growth after β-hydroxy-β-methylbutyrate (HMB) administration in Wistar rats.

    PubMed

    Kuczera, Diogo; Paro de Oliveira, Heloísa Helena; Fonseca Guimarães, Fernando de Souza; de Lima, Carina; Alves, Luciana; Machado, Andressa Franzói; Coelho, Isabela; Yamaguchi, Adriana; Donatti, Lucélia; Naliwaiko, Katya; Fernandes, Luiz Claudio; Nunes, Everson Araújo

    2012-01-01

    This study investigated the mechanisms by which β-hydroxy-β-methylbutyrate (HMB) administration in rats reduces Walker-256 tumor growth. Male Wistar rats were supplemented with HMB (76 mg/kg/day) (HW), or a placebo (W), during 8 wk by gavage. At the 6th wk, rats were inoculated with a suspension of Walker 256 tumor cells (3 × 10(7)/mL). Fifteen days after inoculation, the HW group showed higher glycemia (109.4 ± 5.53 vs. 89.87 ± 7.02 mg/dL, P < 0.05) and lower spleen (1.35 ± 0.05 vs. 1.65 ± 0.12 g, P < 0.05) and tumor weights (9.64 ± 1.07 vs. 13.55 ± 1.19 g, P < 0.05) compared to the W group. Tumor cells extracted from the HMB-treated rats displayed a 36.9% decrement in rates of proliferation ex vivo and a significant increase in the Bax/Bcl-2 protein expression ratio in comparison to those extracted from the placebo-treated rats (P < 0.05). Both phagocytic capacity and H(2)O(2) production rates were higher in polymorphnuclear cells that were obtained from the blood of the HW rats in comparison to those from the W rats (P < 0.05). Reduction of necrotic regions and an intense infiltration of leukocytes and activated granulocytes in HW were evident by transmission electron microscopy. Our findings suggest that HMB supplementation decreases tumor burden by modifying the inner environment of tumor cells and by interfering with blood leukocyte function.

  20. On-chip gradient generation in 256 microfluidic cell cultures: simulation and experimental validation.

    PubMed

    Somaweera, Himali; Haputhanthri, Shehan O; Ibraguimov, Akif; Pappas, Dimitri

    2015-08-07

    A microfluidic diffusion diluter was used to create a stable concentration gradient for dose response studies. The microfluidic diffusion diluter used in this study consisted of 128 culture chambers on each side of the main fluidic channel. A calibration method was used to find unknown concentrations with 12% error. Flow rate dependent studies showed that changing the flow rates generated different gradient patterns. Mathematical simulations using COMSOL Multi-physics were performed to validate the experimental data. The experimental data obtained for the flow rate studies agreed with the simulation results. Cells could be loaded into culture chambers using vacuum actuation and cultured for long times under low shear stress. Decreasing the size of the culture chambers resulted in faster gradient formation (20 min). Mass transport into the side channels of the microfluidic diffusion diluter used in this study is an important factor in creating the gradient using diffusional mixing as a function of the distance. To demonstrate the device's utility, an H2O2 gradient was generated while culturing Ramos cells. Cell viability was assayed in the 256 culture chambers, each at a discrete H2O2 concentration. As expected, the cell viability for the high concentration side channels increased (by injecting H2O2) whereas the cell viability in the low concentration side channels decreased along the chip due to diffusional mixing as a function of distance. COMSOL simulations were used to identify the effective concentration of H2O2 for cell viability in each side chamber at 45 min. The gradient effects were confirmed using traditional H2O2 culture experiments. Viability of cells in the microfluidic device under gradient conditions showed a linear relationship with the viability of the traditional culture experiment. Development of the microfluidic device used in this study could be used to study hundreds of concentrations of a compound in a single experiment.

  1. Antioxidant effects of açaí seed ( Euterpe oleracea ) in anorexia-cachexia syndrome induced by Walker-256 tumor.

    PubMed

    Nascimento, Vitor Hugo Nunes do; Lima, Carla Dos Santos; Paixão, Jorge Tadeu Campos; Freitas, Jofre Jacob da Silva; Kietzer, Katia Simone

    2016-09-01

    To assess antioxidant effects of açaí seed extract on anorexia-cachexia induced by Walker-256 tumor. A population of 20 lab rats were distributed into four groups (n=5): Control Group (CG), which only received tumor inoculation. Experimental Group-100 (EG-100), with animals submitted to tumor inoculation and treated with seed extract in a 100 mg / ml concentration through gavage. Experimental Group-200 (EG-200), with animals submitted to tumor inoculation and treated with seed extract in a 200 mg / ml concentration. Placebo Group (GP), which received tumor inoculation and ethanol-water solution. We analyzed proteolysis, lipid peroxidation, tumor diameter and weight. Lipid peroxidation was representative only in the cerebral cortex, where there was more oxidative stress in rats treated with the extract (p = 0.0276). For proteolysis, there was less muscle damage in untreated rats (p = 0.0312). Only tumor diameter in treated rats was significantly lower (p = 0.0200) compared to untreated ones. The açaí seed extract showed no beneficial effect on the general framework of the cachectic syndrome in lab rats. However, some anticarcinogenic effects were observed in the tumor diameter and weight.

  2. Optimization of polyhydroxybutyrate production by Bacillus sp. CFR 256 with corn steep liquor as a nitrogen source.

    PubMed

    Vijayendra, S V N; Rastogi, N K; Shamala, T R; Anil Kumar, P K; Kshama, L; Joshi, G J

    2007-06-01

    Polyhydroxyalkanotes (PHAs), the eco-friendly biopolymers produced by many bacteria, are gaining importance in curtailing the environmental pollution by replacing the non-biodegradable plastics derived from petroleum. The present study was carried out to economize the polyhydroxybutyrate (PHB) production by optimizing the fermentation medium using corn steep liquor (CSL), a by-product of starch processing industry, as a cheap nitrogen source, by Bacillus sp. CFR 256. Response surface methodology (RSM) was used to optimize the fermentation medium using the variables such as corn steep liquor (5-25 g l(-1)), Na(2)HPO(4) 2H(2)O (2.2-6.2 g l(-1)), KH(2)PO(4) (0.5-2.5 g l(-1)), sucrose (5-55 g l(-1)) and inoculum concentration (1-25 ml l(-1)). Central composite rotatable design (CCRD) experiments were carried out to study the complex interactions of the variables.The optimum conditions for maximum PHB production were (g l(-1)): CSL-25, Na(2)HPO(4) 2H(2)O-2.2, KH(2)PO(4) - 0.5, sucrose - 55 and inoculum - 10 (ml l(-1)). After 72 h of fermentation, the amount of PHA produced was 8.20 g l(-1) (51.20% of dry cell biomass). It is the first report on optimization of fermentation medium using CSL as a nitrogen source, for PHB production by Bacillus sp.

  3. Personalized assessment of radiation risks from the one-stop-shop myocardial 256-slice CT examination.

    PubMed

    Perisinakis, Kostas; Seimenis, Ioannis; Tzedakis, Antonis; Pagonidis, Kostas; Papadakis, Antonios E; Damilakis, John

    2013-10-15

    This study provides data on the cumulative life attributable risk (LAR) of radiation-induced cancer from the combination of coronary CT angiography (CCTA), dynamic CT perfusion (CTP) and delayed enhancement (DE) CT scans, required for reliable risk-benefit analysis of the one-stop-shop CCTA + CTP + DECT cardiac examination. Monte Carlo simulation of the dynamic CTP and DECT exposures on 62 adult individuals was employed to determine radiation absorbed dose to exposed radiosensitive organs. Corresponding data for CCTA were derived using patient chest circumference and previously published data. Individual-specific LARs of cancer were estimated using organ/tissue-specific radiogenic cancer risk factors. Total LAR from CCTA + CTP + DECT scans' sequence were estimated and compared to nominal intrinsic risk of cancer. The main contribution, up to 80%, to cumulative radiation burden from CCTA + CTP + DECT scan-sequence was found to originate from the CTP scan. The total LAR from CCTA + CTP + DECT for females was found 4-6 times higher, compared to males. The mean cumulative risk of radiogenic cancer associated with the complete CCTA + CTP + DECT scan sequence was found to marginally increase the intrinsic risk for cancer induction by less than 0.6% and 0.1% for females and males, respectively. The radiation risk from the 256-slice CCTA + CTP + DECT scan sequence may be considered low and should not constitute an obstacle for the clinical endorsement of the one-stop-shop cardiac CT examination, given that its clinical value has been well verified. Nevertheless, every effort should be made towards optimization of the dynamic CTP component which is the main contributor to patient radiation burden. © 2013.

  4. Development of an intraoperative gamma camera based on a 256-pixel mercuric iodide detector array

    NASA Astrophysics Data System (ADS)

    Patt, B. E.; Tornai, M. P.; Iwanczyk, J. S.; Levin, C. S.; Hoffman, E. J.

    1997-06-01

    A 256-element mercuric iodide (HgI/sub 2/) detector array has been developed which is intended for use as an intraoperative gamma camera (IOGC). The camera is specifically designed for use in imaging gamma-emitting radiopharmaceuticals (such as 99m-Tc labeled Sestamibi) incorporated into brain tumors in the intraoperative surgical environment. The system is intended to improve the success of tumor removal surgeries by allowing more complete removal of subclinical tumor cells without removal of excessive normal tissue. The use of HgI/sub 2/ detector arrays in this application facilitates construction of an imaging head that is very compact and has a high SNR. The detector is configured as a cross-grid array. Pixel dimensions are 1.25 mm squares separated by 0.25 mm. The overall dimension of the detector is 23.75 mm on a side. The detector thickness is 1 mm which corresponds to over 60% stopping at 140 keV. The array has good uniformity with average energy resolution of 5.2/spl plusmn/2.9% FWHM at 140 keV (best resolution was 1.9% FWHM). Response uniformity (/spl plusmn//spl sigma/) was 7.9%. A study utilizing realistic tumor phantoms (uptake ratio varied from 2:1 to 100:1) in background (1 mCi/l) was conducted. SNRs for the reasonably achievable uptake ratio of 50:1 were 5.61 /spl sigma/ with 1 cm of background depth ("normal tissue") and 2.74 /spl sigma/ with 4 cm of background for a 6.3 /spl mu/l tumor phantom (/spl sim/270 nCi at the time of the measurement).

  5. The association between the brain and mind pops: a voxel-based morphometry study in 256 Chinese college students.

    PubMed

    Zhang, Lei; Li, Wenfu; Wei, Dongtao; Yang, Wenjing; Yang, Ning; Qiao, Lei; Qiu, Jiang; Zuo, Xi-Nian; Zhang, Qinglin

    2016-06-01

    Mind pops or involuntary semantic memories refer to words, phrases, images, or melodies that suddenly pop into one's mind without any deliberate attempt to recall them. Despite their prevalence in everyday life, research on mind pops has started only recently. Notably, mind pops are very similar to clinical involuntary phenomena such as hallucinations in schizophrenia, suggesting their potential role in pathology. The present study aimed to investigate the relationship between mind pops and the brain morphometry measured in 302 healthy young adults; after exclusions, 256 participants were included in our analyses. Specifically, the Mind Popping Questionnaire (MPQ) was employed to measure the degree of individual mind pops, whereas the Voxel-Based Morphometry (VBM) was used to compute the volumes of both gray and white matter tissues. Multiple regression analyses on MPQ and VBM metrics indicated that high-frequency mind pops were significantly associated with smaller gray matter volume in the left middle temporal gyrus as well as with larger gray and white matter volume in the right medial prefrontal cortex. This increase in mind pops is also linked to higher creativity and the personality trait of 'openness'. These data not only suggest a key role of the two regions in generating self-related thoughts, but also open a possible link between brain and creativity or personality.

  6. A 256-channel, high throughput and precision time-to-digital converter with a decomposition encoding scheme in a Kintex-7 FPGA

    NASA Astrophysics Data System (ADS)

    Song, Z.; Wang, Y.; Kuang, J.

    2018-05-01

    Field Programmable Gate Arrays (FPGAs) made with 28 nm and more advanced process technology have great potentials for implementation of high precision time-to-digital convertors (TDC), because the delay cells in the tapped delay line (TDL) used for time interpolation are getting smaller and smaller. However, the bubble problems in the TDL status are becoming more complicated, which make it difficult to achieve TDCs on these chips with a high time precision. In this paper, we are proposing a novel decomposition encoding scheme, which not only can solve the bubble problem easily, but also has a high encoding efficiency. The potential of these chips to realize TDC can be fully released with the scheme. In a Xilinx Kintex-7 FPGA chip, we implemented a TDC system with 256 TDC channels, which doubles the number of TDC channels that our previous technique could achieve. Performances of all these TDC channels are evaluated. The average RMS time precision among them is 10.23 ps in the time-interval measurement range of (0–10 ns), and their measurement throughput reaches 277 M measures per second.

  7. The effect of head size/shape, miscentering, and bowtie filter on peak patient tissue doses from modern brain perfusion 256-slice CT: How can we minimize the risk for deterministic effects?

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Perisinakis, Kostas; Seimenis, Ioannis; Tzedakis, Antonis

    Purpose: To determine patient-specific absorbed peak doses to skin, eye lens, brain parenchyma, and cranial red bone marrow (RBM) of adult individuals subjected to low-dose brain perfusion CT studies on a 256-slice CT scanner, and investigate the effect of patient head size/shape, head position during the examination and bowtie filter used on peak tissue doses. Methods: The peak doses to eye lens, skin, brain, and RBM were measured in 106 individual-specific adult head phantoms subjected to the standard low-dose brain perfusion CT on a 256-slice CT scanner using a novel Monte Carlo simulation software dedicated for patient CT dosimetry. Peakmore » tissue doses were compared to corresponding thresholds for induction of cataract, erythema, cerebrovascular disease, and depression of hematopoiesis, respectively. The effects of patient head size/shape, head position during acquisition and bowtie filter used on resulting peak patient tissue doses were investigated. The effect of eye-lens position in the scanned head region was also investigated. The effect of miscentering and use of narrow bowtie filter on image quality was assessed. Results: The mean peak doses to eye lens, skin, brain, and RBM were found to be 124, 120, 95, and 163 mGy, respectively. The effect of patient head size and shape on peak tissue doses was found to be minimal since maximum differences were less than 7%. Patient head miscentering and bowtie filter selection were found to have a considerable effect on peak tissue doses. The peak eye-lens dose saving achieved by elevating head by 4 cm with respect to isocenter and using a narrow wedge filter was found to approach 50%. When the eye lies outside of the primarily irradiated head region, the dose to eye lens was found to drop to less than 20% of the corresponding dose measured when the eye lens was located in the middle of the x-ray beam. Positioning head phantom off-isocenter by 4 cm and employing a narrow wedge filter results in a moderate

  8. Immunological mechanism of low-dose priming radiation resistance in walker-256 tumor model mice

    PubMed Central

    Feng, Li; Qin, Ling; Guo, Dan; Deng, Daping; Lu, Feng; Li, Hailiang; Bao, Narisu; Yang, Xiting; Ding, Hongyu; Li, Jianguo

    2017-01-01

    The aim of the present study was to investigate whether low-dose priming radiation induces antitumor immunity that can be augmented by the modulation of natural killer (NK) cell and cytokine activity using a mouse tumor model. Walker-256 cells were injected into the right flank of male BALB/c mice. At 7 days after inoculation, mice were divided into three groups, including group 1,2,3. In group 1 the mice were without radiation, in group 2 the mice were received 2 Gy radiation only, and in group 3 the mice were radiated with a priming dose of 75 mGy followed by 2 Gy radiation after 24 h. On day 21 following the radiation, the tumors were removed and the tumor index (tumor weight as a percentage of body weight) was calculated. At 1, 7, 14 and 21 days following the 2 Gy radiation, mouse splenocytes were isolated to analyze the NK activity and measure the production of the cytokines interleukin-1β, interferon-γ and tumor necrosis factor-α by ELISA. Apoptosis was also measured by flow cytometry. The results demonstrated that priming radiation significantly delayed the tumor growth and prolonged the median survival time to 38 days compared with the 31-day survival in the 2 Gy radiation group. The percentage of apoptotic cells was significantly higher in the mice that received 75 mGy + 2 Gy radiation compared with that in the mice that received 2 Gy alone; by contrast, mice that were not irradiated exhibited a relatively low level of apoptosis. The primed mice had a higher level of NK activity as compared with the mice exposed to 2 Gy radiation only or mice that were not irradiated. Furthermore, cytokine expression remained at a higher level in mice receiving priming dose of radiation compared that in the mice receiving only 2 Gy radiation. In conclusion, the results indicated that low-dose priming X-ray radiation may enhance the NK activity and the levels of cytokines, and that the immune response serves an important role in anticancer therapy, including radiotherapy

  9. Low-Dose Cannabinoid Type 2 Receptor Agonist Attenuates Tolerance to Repeated Morphine Administration via Regulating μ-Opioid Receptor Expression in Walker 256 Tumor-Bearing Rats.

    PubMed

    Zhang, Mingyue; Wang, Kun; Ma, Min; Tian, Songyu; Wei, Na; Wang, Guonian

    2016-04-01

    Morphine is widely used in patients with moderate and severe cancer pain, whereas the development of drug tolerance remains a major problem associated with opioid use. Previous studies have shown that cannabinoid type 2 (CB2) receptor agonists induce morphine analgesia, attenuate morphine tolerance in normal and neuropathic pain animals, induce transcription of the μ-opioid receptor (MOR) gene in Jurkat T cells, and increase morphine analgesia in cancer pain animals. However, no studies of the effects of CB2 receptor agonists on morphine tolerance in cancer pain have been performed. Therefore, we investigated the effect of repeated intrathecal (IT) injection of the low-dose CB2 receptor agonist AM1241 on the development of morphine tolerance in walker 256 tumor-bearing rats. We also tested the influence of the CB2 receptor agonist AM1241 on MOR protein and messenger ribonucleic acid (mRNA) expression in the rat spinal cord and dorsal root ganglia (DRG). Walker 256 cells were implanted into the plantar region of each rat's right hindpaw. Tumor-bearing rats received IT injection of the CB2 receptor agonist AM1241 or antagonist AM630 with or without morphine subcutaneously twice daily for 8 days. Rats receiving drug vehicle only served as the control group. Mechanical paw withdrawal threshold and thermal paw withdrawal latency were assessed by a von Frey test and hot plate test 30 minutes after drug administration every day. MOR protein and mRNA expression in the spinal cord and DRG were detected after the last day (day 8) of drug administration via Western blot and real-time reverse transcription polymerase chain reaction. The data were analyzed via analysis of variance followed by Student t test with Bonferroni correction for multiple comparisons. Repeated morphine treatments reduced the mechanical withdrawal threshold and thermal latency. Coadministration of a nonanalgetic dose of the CB2 receptor agonist AM1241 with morphine significantly inhibited the

  10. Mortality and Epidemiology in 256 Cases of Pediatric Traumatic Brain Injury: Korean Neuro-Trauma Data Bank System (KNTDBS) 2010-2014.

    PubMed

    Jeong, Hee-Won; Choi, Seung-Won; Youm, Jin-Young; Lim, Jeong-Wook; Kwon, Hyon-Jo; Song, Shi-Hun

    2017-11-01

    Among pediatric injury, brain injury is a leading cause of death and disability. To improve outcomes, many developed countries built neurotrauma databank (NTDB) system but there was not established nationwide coverage NTDB until 2009 and there have been few studies on pediatric traumatic head injury (THI) patients in Korea. Therefore, we analyzed epidemiology and outcome from the big data of pediatric THI. We collected data on pediatric patients from 23 university hospitals including 9 regional trauma centers from 2010 to 2014 and analyzed their clinical factors (sex, age, initial Glasgow coma scale, cause and mechanism of head injury, presence of surgery). Among all the 2617 THI patients, total number of pediatric patients was 256. The average age of the subjects was 9.07 (standard deviation±6.3) years old. The male-to female ratio was 1.87 to 1 and male dominance increases with age. The most common cause for trauma were falls and traffic accidents. Age ( p =0.007), surgery ( p <0.001), mechanism of trauma ( p =0.016), subdural hemorrhage (SDH) ( p <0.001), diffuse axonal injury (DAI) ( p <0.001) were statistically significant associated with severe brain injury. Falls were the most common cause of trauma, and age, surgery, mechanism of trauma, SDH, DAI increased with injury severity. There is a critical need for effective fall and traffic accidents prevention strategies for children, and we should give attention to these predicting factors for more effective care.

  11. Insulin, not glutamine dipeptide, reduces lipases expression and prevents fat wasting and weight loss in Walker 256 tumor-bearing rats.

    PubMed

    de Morais, Hely; de Fatima Silva, Flaviane; da Silva, Francemilson Goulart; Silva, Milene Ortiz; Graciano, Maria Fernanda Rodrigues; Martins, Maria Isabel Lovo; Carpinelli, Ângelo Rafael; Mazucco, Tânia Longo; Bazotte, Roberto Barbosa; de Souza, Helenir Medri

    2017-07-05

    Cachexia is the main cause of mortality in advanced cancer patients. We investigated the effects of insulin (INS) and glutamine dipeptide (GDP), isolated or associated, on cachexia and metabolic changes induced by Walker 256 tumor in rats. INS (NPH, 40 UI/kg, sc) or GDP (1.5g/kg, oral gavage) was once-daily administered during 11 days after tumor cell inoculation. GDP, INS or INS+GDP treatments did not influence the tumor growth. However, INS and INS+GDP prevented retroperitoneal fat wasting and body weight loss of tumor-bearing rats. In consistency, INS and INS+GDP prevented the increased expression of triacylglycerol lipase (ATGL) and hormone sensitive lipase (HSL), without changing the expression of tumor necrosis factor α (TNF-α) and interleukin-6 (IL-6) in the retroperitoneal adipose tissue of tumor-bearing rats. INS and INS+GDP also prevented anorexia and hyperlactatemia of tumor-bearing rats. However, INS and INS+GDP accentuated the loss of muscle mass (gastrocnemius, soleus and long digital extensor) without affecting the myostatin expression in the gastrocnemius muscle and blood corticosterone. GDP treatment did not promote beneficial effects. It can be concluded that treatment with INS (INS or INS+GDP), not with GDP, prevented fat wasting and weight loss in tumor-bearing rats without reducing tumor growth. These effects might be attributed to the reduction of lipases expression (ATGL and LHS) and increased food intake. The results show the physiological function of INS in the suppression of lipolysis induced by cachexia mediators in tumor-bearing rats. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. KSC-98pc256

    NASA Image and Video Library

    1998-01-31

    KENNEDY SPACE CENTER, Fla. -- The Space Shuttle orbiter Endeavour touches down on Runway 15 of the KSC Shuttle Landing Facility (SLF) to complete the nearly nine-day STS-89 mission. Main gear touchdown was at 5:35:09 p.m. EST on Jan. 31, 1998. The wheels stopped at 5:36:19 EST, completing a total mission time of eight days, 19 hours, 48 minutes and four seconds. The 89th Space Shuttle mission was the 42nd (and 13th consecutive) landing of the orbiter at KSC, and STS-89 was the eighth of nine planned dockings of the Space Shuttle with the Russian Space Station Mir. STS-89 Mission Specialist Andrew Thomas, Ph.D., succeeded NASA astronaut and Mir 24 crew member David Wolf, M.D., who was on the Russian space station since late September 1997. Dr. Wolf returned to Earth on Endeavour with the remainder of the STS-89 crew, including Commander Terrence Wilcutt; Pilot Joe Edwards Jr.; and Mission Specialists James Reilly, Ph.D.; Michael Anderson; Bonnie Dunbar, Ph.D.; and Salizhan Sharipov with the Russian Space Agency. Dr. Thomas is scheduled to remain on Mir until the STS-91 Shuttle mission returns in June 1998. In addition to the docking and crew exchange, STS-89 included the transfer of science, logistical equipment and supplies between the two orbiting spacecrafts

  13. Dual-Use of Compact HF Radars for the Detection of Mid-and Large-size Vessels

    DTIC Science & Technology

    2010-01-01

    make detecting a ship nearby very difficult. The zero-Doppler is from signals returned from any stationary object wile the sea-echo Bragg peaks are due...the six detection processes IIR-128 (blue), IIR-256 (red), IIR-256 (magenta), Median-64 (dark brown ), Median-128 ( brown ), Median-256 (dark green). As...IIR-256 (red), IIR-256 (magenta), Median-64 (dark brown ), Median-128 ( brown ), Median-256 (dark green). Acknowledgements This work was funded by the

  14. Novel Nonsense Variants c.58C>T (p.Q20X) and c.256G>T (p.E85X) in the CHEK2 Gene Identified in Breast Cancer Patients from Balochistan.

    PubMed

    Baloch, Abdul Hameed; Khosa, Ahmad Nawaz; Bangulzai, Nasrullah; Shuja, Jamila; Naseeb, Hafiz Khush; Jan, Mohammad; Marghazani, Illahi Bakhsh; Kakar, MasoodulHaq; Baloch, Dost Mohammad; Cheema, Abdul Majeed; Ahmad, Jamil

    2016-01-01

    Breast cancer is very common and the leading cause of cancer deaths among women globally. Hereditary cases account for 510% of the total burden and CHEK2, which plays crucial role in response to DNA damage to promote cell cycle arrest and repair or induce apoptosis, is considered as a moderate penetrance breast cancer risk gene. Our objective in the current study was to analyze mutations in related to breast cancer. A total of 271 individuals including breast cancer patients and normal subjects were enrolled and all 14 exons of CHEK2 were amplified and sequenced. The majority of the patients (>95%) were affected with invasive ductal carcinoma (IDC), 52.1% were diagnosed with grade III tumors and 56.2% and 27.5% with advanced stages III and IV. Two novel nonsense variants i.e. c.58C>T (P.Q20X) and c.256G>T (p.E85X) at exon 1 and 2 in two breast cancer patients were identified, both novel and not reported elsewhere.

  15. MT3250BA: a 320×256-50µm snapshot microbolometer ROIC for high-resistance detector arrays

    NASA Astrophysics Data System (ADS)

    Eminoglu, Selim; Akin, Tayfun

    2013-06-01

    This paper reports the development of a new microbolometer readout integrated circuit (MT3250BA) designed for high-resistance detector arrays. MT3250BA is the first microbolometer readout integrated circuit (ROIC) product from Mikro-Tasarim Ltd., which is a fabless IC design house specialized in the development of monolithic CMOS imaging sensors and ROICs for hybrid photonic imaging sensors and microbolometers. MT3250BA has a format of 320 × 256 and a pixel pitch of 50 µm, developed with a system-on-chip architecture in mind, where all the timing and biasing for this ROIC are generated on-chip without requiring any external inputs. MT3250BA is a highly configurable ROIC, where many of its features can be programmed through a 3-wire serial interface allowing on-the-fly configuration of many ROIC features. MT3250BA has 2 analog video outputs and 1 analog reference output for pseudo-differential operation, and the ROIC can be programmed to operate in the 1 or 2-output modes. A unique feature of MT3250BA is that it performs snapshot readout operation; therefore, the image quality will only be limited by the thermal time constant of the detector pixels, but not by the scanning speed of the ROIC, as commonly found in the conventional microbolometer ROICs performing line-by-line (rolling-line) readout operation. The signal integration is performed at the pixel level in parallel for the whole array, and signal integration time can be programmed from 0.1 µs up to 100 ms in steps of 0.1 µs. The ROIC is designed to work with high-resistance detector arrays with pixel resistance values higher than 250 kΩ. The detector bias voltage can be programmed on-chip over a 2 V range with a resolution of 1 mV. The ROIC has a measured input referred noise of 260 µV rms at 300 K. The ROIC can be used to build a microbolometer infrared sensor with an NETD value below 100 mK using a microbolometer detector array fabrication technology with a high detector resistance value (≥ 250 K

  16. 40 CFR 256.10 - Requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Identification of Responsibilities... guidelines for identification of regions and agencies for solid waste management (40 CFR part 255), the State...

  17. 40 CFR 256.11 - Recommendations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Identification of Responsibilities... facilities. (d) Responsibilities should be identified for the development and implementation of the...

  18. 40 CFR 256.10 - Requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Identification of Responsibilities... guidelines for identification of regions and agencies for solid waste management (40 CFR part 255), the State...

  19. 40 CFR 256.10 - Requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Identification of Responsibilities... guidelines for identification of regions and agencies for solid waste management (40 CFR part 255), the State...

  20. 40 CFR 256.10 - Requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Identification of Responsibilities... guidelines for identification of regions and agencies for solid waste management (40 CFR part 255), the State...

  1. 40 CFR 256.10 - Requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Identification of Responsibilities... guidelines for identification of regions and agencies for solid waste management (40 CFR part 255), the State...

  2. 30 CFR 256.4 - Authority.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas, and Sulphur Management, General... Secretary of the Interior to issue, on a competitive basis, leases for oil and gas, and sulphur, in...

  3. 30 CFR 256.4 - Authority.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas... for oil and gas, and sulphur, in submerged lands of the outer Continental Shelf (OCS). The Act... major oil and gas producers. [64 FR 72795, Dec. 28, 1999] ...

  4. 30 CFR 256.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas, and... administer a leasing program for oil, gas and sulphur. The procedures under which the Secretary will exercise...

  5. 25 CFR 256.2 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... parental support by tribal or state law (if any) applicable to the person at his or her residence, except... construction must conform to applicable tribal, county, State, or national codes and to appropriate building... of severe climate, the size of the house may be reduced to meet the region's applicable building...

  6. 25 CFR 256.2 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... parental support by tribal or state law (if any) applicable to the person at his or her residence, except... construction must conform to applicable tribal, county, State, or national codes and to appropriate building... of severe climate, the size of the house may be reduced to meet the region's applicable building...

  7. 25 CFR 256.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... parental support by tribal or state law (if any) applicable to the person at his or her residence, except... construction must conform to applicable tribal, county, State, or national codes and to appropriate building... of severe climate, the size of the house may be reduced to meet the region's applicable building...

  8. 15 CFR 256.1 - Introduction.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... facilities available to persons other than Bureau employees to work with scientists and engineers in collaborative research aimed at furthering the Nation's scientific, industrial, and economic growth. Such cooperative programs may be sponsored by professional, technical, or industrial organizations or associations...

  9. 30 CFR 256.11 - Helium.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the manner required by the United States to such plants or reduction works as the United States may provide. (c) The extraction of helium shall not cause a reduction in the value of the lessee's gas or any... necessary for the extraction of helium. The extraction of helium shall not cause substantial delays in the...

  10. 30 CFR 256.11 - Helium.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    .... Delivery shall be made in the manner required by the United States to such plants or reduction works as the United States may provide. (c) The extraction of helium shall not cause a reduction in the value of the... and other equipment necessary for the extraction of helium. The extraction of helium shall not cause...

  11. 25 CFR 256.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... standards for the region; (ii) The heating system must have the capacity to maintain a minimum temperature... economical access to utilities and must be easy to enter and leave; and (ix) Aesthetics and access to school...

  12. 32 CFR 256.4 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... installations and neighboring civilian communities by means of a compatible land use planning and control.... In all instances the primary objective will be to identify planning areas and reasonable land use guidelines which will be recommended to appropriate agencies who are in control of the planning functions for...

  13. 32 CFR 256.4 - Policy.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... installations and neighboring civilian communities by means of a compatible land use planning and control.... In all instances the primary objective will be to identify planning areas and reasonable land use guidelines which will be recommended to appropriate agencies who are in control of the planning functions for...

  14. 37 CFR 2.56 - Specimens.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... exceeding these size requirements (a “bulky specimen”), the Office will create a digital facsimile of the... bulky specimen. (3) In the absence of non-bulky alternatives, the Office may accept an audio or video...

  15. 15 CFR 256.1 - Introduction.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... facilities available to persons other than Bureau employees to work with scientists and engineers in collaborative research aimed at furthering the Nation's scientific, industrial, and economic growth. Such cooperative programs may be sponsored by professional, technical, or industrial organizations or associations...

  16. 49 CFR 256.5 - Eligibility.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... reasonable opportunity to review and comment upon the project as it affects property listed or eligible for... passenger terminal, features which appear reasonably likely to attract private investors willing to finance...

  17. 37 CFR 2.56 - Specimens.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... advertising of the services in commerce. (b)(1) A trademark specimen is a label, tag, or container for the... actually used in the sale or advertising of the services. (3) A collective trademark or collective service mark specimen must show how a member uses the mark on the member's goods or in the sale or advertising...

  18. 40 CFR 256.30 - Requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... law from entering into long-term contracts for the supply of solid waste to resource recovery... AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Resource Conservation and Resource Recovery... resource conservation and recovery, the State plan shall provide for a policy and strategy for...

  19. 40 CFR 256.30 - Requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... law from entering into long-term contracts for the supply of solid waste to resource recovery... AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Resource Conservation and Resource Recovery... resource conservation and recovery, the State plan shall provide for a policy and strategy for...

  20. 40 CFR 256.30 - Requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... law from entering into long-term contracts for the supply of solid waste to resource recovery... AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Resource Conservation and Resource Recovery... resource conservation and recovery, the State plan shall provide for a policy and strategy for...

  1. 40 CFR 256.30 - Requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... law from entering into long-term contracts for the supply of solid waste to resource recovery... AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Resource Conservation and Resource Recovery... resource conservation and recovery, the State plan shall provide for a policy and strategy for...

  2. 40 CFR 256.30 - Requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... law from entering into long-term contracts for the supply of solid waste to resource recovery... AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Resource Conservation and Resource Recovery... resource conservation and recovery, the State plan shall provide for a policy and strategy for...

  3. 30 CFR 256.5 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., conditions, and quality of the marine ecosystem, including the waters of the high seas, the contiguous zone..., conditions, and factors which interactively determine the productivity, state, conditions, and quality of the... determine the state, condition, and quality of living conditions, employment, and health of those affected...

  4. 40 CFR 256.50 - Requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... underground sources of drinking water under the authority of section 1442(a)(8)(C) of the Safe Drinking Water... Drinking Water Act (42 U.S.C. 300f et seq.) and with the designation of sole source aquifers under section... recovery and solid waste disposal programs at various installations); (8) Department of Energy (State...

  5. 40 CFR 256.50 - Requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... underground sources of drinking water under the authority of section 1442(a)(8)(C) of the Safe Drinking Water... Drinking Water Act (42 U.S.C. 300f et seq.) and with the designation of sole source aquifers under section... recovery and solid waste disposal programs at various installations); (8) Department of Energy (State...

  6. 40 CFR 256.50 - Requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... underground sources of drinking water under the authority of section 1442(a)(8)(C) of the Safe Drinking Water... Drinking Water Act (42 U.S.C. 300f et seq.) and with the designation of sole source aquifers under section... recovery and solid waste disposal programs at various installations); (8) Department of Energy (State...

  7. 40 CFR 256.50 - Requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... underground sources of drinking water under the authority of section 1442(a)(8)(C) of the Safe Drinking Water... Drinking Water Act (42 U.S.C. 300f et seq.) and with the designation of sole source aquifers under section... recovery and solid waste disposal programs at various installations); (8) Department of Energy (State...

  8. 40 CFR 256.50 - Requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... underground sources of drinking water under the authority of section 1442(a)(8)(C) of the Safe Drinking Water... Drinking Water Act (42 U.S.C. 300f et seq.) and with the designation of sole source aquifers under section... recovery and solid waste disposal programs at various installations); (8) Department of Energy (State...

  9. 49 CFR 256.11 - Applications.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... accordance with appendix M of Office of Management and Budget Circular A-102, applicants shall use the pre... appendix M of Office of Management and Budget Circular A-102. Applicants shall include under Part IV... of Management and Budget Circular A-102, adequate procedures for financial control, accounting, and...

  10. 49 CFR 256.3 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... and others, and other public activities supported in whole or in part under Federal law. (g) Council...: Intercity bus, commuter rail, intra-city rail transit and bus transportation, airport limousine service and... Railroad Revitalization and Regulatory Reform Act of 1976, as amended, Public Law 94-210, 90 Stat. 125, 49...

  11. 17 CFR 256.931 - Rents.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... property of others used, occupied or operated in connection with service company functions. Provide..., computers, data processing equipment, micro-wave and telecommunication equipment, airplanes, automobiles...

  12. 17 CFR 256.307 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., communications and dispatching, automatic data processing, information storage and retrieval, research and laboratory testing, construction, meter repairing, and printing and stationery. Subaccounts shall be...

  13. 40 CFR 256.11 - Recommendations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... authorized State hazardous waste management program under subtitle C of the Act. (e) The State plan should... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Identification of Responsibilities...

  14. 40 CFR 256.11 - Recommendations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... authorized State hazardous waste management program under subtitle C of the Act. (e) The State plan should... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Identification of Responsibilities...

  15. 25 CFR 256.2 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... construction must conform to applicable tribal, county, State, or national codes and to appropriate building... that is claimed to adversely affect the interested party making the request, as provided in part 2 of... (including lands owned by corporations established pursuant to the Alaska Native Claims Settlement Act...

  16. 30 CFR 256.5 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... productivity, state, conditions, and quality of the marine ecosystem, including the waters of the high seas..., conditions, and quality of the terrestrial ecosystem from the shoreline inward to the boundaries of the... factors which interactively determine the state, condition, and quality of living conditions, employment...

  17. 30 CFR 256.40 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... products means natural gas liquid products including the following: ethane, propane, butane, pentane... resulting from the removal of natural gas liquids and nonhydrocarbon gases. (3) Of liquefied petroleum products means the volume of natural gas liquids produced from reservoir gas and liquefied at surface...

  18. 30 CFR 256.40 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... interest. (g) Liquefied petroleum products means natural gas liquid products including the following... liquids and nonhydrocarbon gases. (3) Of liquefied petroleum products means the volume of natural gas liquids produced from reservoir gas and liquefied at surface separators, field facilities, or gas...

  19. 32 CFR 256.3 - Criteria.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... assumptions and data upon which these guidelines are based and require individual study. Where it is desirable to restrict the density of development of an area, it is not usually possible to state that one... wind conditions are such that a large percentage (i.e., over 80 percent) of the operations are in one...

  20. 32 CFR 256.3 - Criteria.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... assumptions and data upon which these guidelines are based and require individual study. Where it is desirable to restrict the density of development of an area, it is not usually possible to state that one... wind conditions are such that a large percentage (i.e., over 80 percent) of the operations are in one...

  1. 30 CFR 256.22 - General.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... area. [51 FR 6107, Feb. 20, 1986] ... Director shall prepare a report describing the general geology and potential mineral resources of the area... describing, to the extent known, any other valuable resources contained within the general area and the...

  2. 30 CFR 256.22 - General.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... contained within the general area and the potential effect of mineral operations upon the resources or upon the total environment or other uses of the area. [51 FR 6107, Feb. 20, 1986] ... potential mineral resources of the area under consideration. The Director may request other interested...

  3. Providing Cryptographic Security and Evidentiary Chain-of-Custody with the Advanced Forensic Format, Library, and Tools

    DTIC Science & Technology

    2008-08-19

    1 hash of the page page%d sha256 The segment for the SHA256 hash of the page Bad Sector Management: badsectors The number of sectors in the image...written, AFFLIB can automatically compute the page’s MD5, SHA-1, and/or SHA256 hash and write an associated segment containing the hash value. The...are written into segments themselves, with the segment name being name/ sha256 where name is the original segment name sha256 is the hash algorithm used

  4. Sensor Agent Processing Software (SAPS)

    DTIC Science & Technology

    2004-05-01

    buildings, sewers, and tunnels. The time scale governs many aspects of tactical sensing. In high intensity combat situations forces move within...21 Figure 9-2 BAE Systems Sitex00 High Bandwidth...float) Subscribers Subscribers Preprocessor Channel 1 xout[256] Data File in Memory xout[256] S w i t c h High Pass Filter (IIR) xin[256] xout[256

  5. 40 CFR Table A-7 to Subpart A of... - Data Elements That Are Inputs to Emission Equations and for Which the Reporting Deadline Is March...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... mass balance equation. K 98.116(b) Only annual production by product from each EAF (No CEMS). K 98.116... contributed by methane. Y 98.256(f)(7) Only molar volume conversion factor. Y 98.256(f)(10) Only coke burn-off... methane in coking gas. Y 98.256(l)(5) Only molar volume conversion factor. Y 98.256(m)(3) Only total...

  6. Novel Nonsense Variants c.58C>T (p.Q20X) and c.256G>T (p.E85X) in the CHEK2 Gene Identified dentified in Breast Cancer Patients from Balochistan.

    PubMed

    Baloch, Abdul Hameed; Khosa, Ahmad Nawaz; Bangulzai, Nasrullah; Shuja, Jamila; Naseeb, Hafiz Khush; Jan, Mohammad; Marghazani, Illahi Bakhsh; Kakar, Masood-Ul-Haq; Baloch, Dost Mohammad; Cheema, Abdul Majeed; Ahmad, Jamil

    2016-01-01

    Breast cancer is the most commonly occurring and leading cause of cancer deaths among women globally. Hereditary cases account 5-10% of all the cases and CHEK2 is considered as a moderate penetrance breast cancer risk gene. CHEK2 plays a crucial role in response to DNA damage to promote cell cycle arrest and repair DNA damage or induce apoptosis. Our objective in the current study was to analyze mutations in the CHEK2 gene related to breast cancer in Balochistan. A total of 271 individuals including breast cancer patients and normal subjects were enrolled. All 14 exons of CHEK2 were amplified and sequenced. The majority of the patients (>95%) had invasive ductal carcinomas (IDCs), 52.1% were diagnosed with tumor grade III and 56.1% and 27.5% were diagnosed with advance stages III and IV. Two novel nonsense variants i.e. c.58C>T (P.Q20X) and c.256G>T (p.E85X) at exon 1 and 2 in two breast cancer patients were identified in the current study. Both the variants identified were novel and have not been reported elsewhere.

  7. High-frame rate multiport CCD imager and camera

    NASA Astrophysics Data System (ADS)

    Levine, Peter A.; Patterson, David R.; Esposito, Benjamin J.; Tower, John R.; Lawler, William B.

    1993-01-01

    A high frame rate visible CCD camera capable of operation up to 200 frames per second is described. The camera produces a 256 X 256 pixel image by using one quadrant of a 512 X 512 16-port, back illuminated CCD imager. Four contiguous outputs are digitally reformatted into a correct, 256 X 256 image. This paper details the architecture and timing used for the CCD drive circuits, analog processing, and the digital reformatter.

  8. Image Filtering with Boolean and Statistical Operators.

    DTIC Science & Technology

    1983-12-01

    S3(2) COMPLEX AMAT(256, 4). BMAT (256. 4). CMAT(256. 4) CALL IOF(3. MAIN. AFLNM. DFLNI, CFLNM. MS., 82, S3) CALL OPEN(1.AFLNM* 1.IER) CALL CHECKC!ER...RDBLK(2. 6164. MAT. 16, IER) CALL CHECK(IER) DO I K-1. 4 DO I J-1.256 CMAT(J. K)-AMAT(J. K)’. BMAT (J. K) I CONTINUE S CALL WRBLK(3. 164!. CMAT. 16. IER

  9. Some aspects of adaptive transform coding of multispectral data

    NASA Technical Reports Server (NTRS)

    Ahmed, N.; Natarajan, T.

    1977-01-01

    This paper concerns a data compression study pertaining to multi-spectral scanner (MSS) data. The motivation for this undertaking is the need for securing data compression of images obtained in connection with the Landsat Follow-On Mission, where a compression of at least 6:1 is required. The MSS data used in this study consisted of four scenes: Tristate, consisting of 256 pels per row and a total of 512 rows - i.e., (256x512), (2) Sacramento (256x512), (3) Portland (256x512), and (4) Bald Knob (200x256). All these scenes were on digital tape at 6 bits/pel. The corresponding reconstructed scenes of 1 bit/pel (i.e., a 6:1 compression) are included.

  10. 47 CFR 15.214 - Cordless telephones.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... discrete digital codes. Factory-set codes must be continuously varied over at least 256 possible codes as... readily select from among at least 256 possible discrete digital codes. The cordless telephone shall be... fixed code that is continuously varied among at least 256 discrete digital codes as each telephone is...

  11. 17 CFR 256.00-1 - Preface.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... reimbursable costs and charges to customers, and (3) account for compensation for use of capital, if paid. (d... OF ACCOUNTS FOR MUTUAL SERVICE COMPANIES AND SUBSIDIARY SERVICE COMPANIES, PUBLIC UTILITY HOLDING... Accounts for Mutual Service and Subsidiary Service Companies represents a modernization of the accounting...

  12. 17 CFR 256.236 - Taxes accrued.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... credited with the amount of taxes accrued during the accounting period, corresponding debits being made to... be kept so as to show for each class of taxes the amount accrued, the basis for the accrual, the...

  13. 17 CFR 256.231 - Notes payable.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... the face value of all notes, drafts, acceptances, or other similar evidences of indebtedness, payable on demand or within a time not exceeding one year from date of issue, to other than associate...

  14. 30 CFR 256.7 - Cross references.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., see 30 CFR part 290. (c) For multiple use conflicts, see the Environmental Protection Agency listing..., 50 CFR part 296; (3) Coastal Energy Impact Program, 15 CFR part 931; (e) For Coast Guard regulations...

  15. 30 CFR 256.7 - Cross references.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., see 30 CFR part 290. (c) For multiple use conflicts, see the Environmental Protection Agency listing..., 50 CFR part 296; (3) Coastal Energy Impact Program, 15 CFR part 931; (e) For Coast Guard regulations...

  16. 7 CFR 868.256 - Milling requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... FOR CERTAIN AGRICULTURAL COMMODITIES United States Standards for Brown Rice for Processing Principles....252(g)) in brown rice for processing, the degree of milling shall be equal to, or better than, that of the interpretive line sample for “well-milled” rice. [42 FR 40869, Aug. 12, 1977. Redesignated at...

  17. 7 CFR 868.256 - Milling requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... FOR CERTAIN AGRICULTURAL COMMODITIES United States Standards for Brown Rice for Processing Principles....252(g)) in brown rice for processing, the degree of milling shall be equal to, or better than, that of the interpretive line sample for “well-milled” rice. [42 FR 40869, Aug. 12, 1977. Redesignated at...

  18. 30 CFR 256.31 - State comments.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... interest and the well-being of the citizens of the affected State. A determination of the national interest... a reasonable balance between the national interest and the well-being of the citizens of the...

  19. 17 CFR 256.924 - Property insurance.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... insurance premiums to protect the service company against losses and damages to owned or leased property... covered, and the applicable premiums. Any dividends distributed by mutual insurance companies shall be credited to the accounts to which the insurance premiums were charged. ...

  20. 17 CFR 256.924 - Property insurance.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... insurance premiums to protect the service company against losses and damages to owned or leased property... covered, and the applicable premiums. Any dividends distributed by mutual insurance companies shall be credited to the accounts to which the insurance premiums were charged. ...

  1. 40 CFR 96.256 - Account error.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS CAIR SO2 Allowance... her own motion, correct any error in any CAIR SO2 Allowance Tracking System account. Within 10...

  2. 49 CFR 256.7 - Financial assistance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... passenger terminal, under subsection 4(i)(2) of the Act, may be expended for the following project costs incurred after the date of final project approval: (1) Acquisition or long-term lease of real property or... project implementation; (2) Final architectural and engineering construction documentation, including all...

  3. 76 FR 256 - Informed Consent Elements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-04

    ... societies, trade organizations representing clinical research organizations, drug and device sponsors, blood banks, clinical research organizations, research hospitals, medical device manufacturers, nonprofit... Administration Amendments Act of 2007 (FDAAA) and is designed to promote transparency of clinical research to...

  4. 30 CFR 256.7 - Cross references.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., see 30 CFR part 290. (c) For multiple use conflicts, see the Environmental Protection Agency listing..., 50 CFR part 296; (3) Coastal Energy Impact Program, 15 CFR part 931; (e) For Coast Guard regulations...

  5. 30 CFR 256.7 - Cross references.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., see 30 CFR part 290. (c) For multiple use conflicts, see the Environmental Protection Agency listing..., 50 CFR part 296; (3) Coastal Energy Impact Program, 15 CFR part 931; (e) For Coast Guard regulations...

  6. 30 CFR 256.7 - Cross references.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... multiple use conflicts, see the Environmental Protection Agency listing of ocean dumping sites—40 CFR part... sanctuary regulations, 15 CFR part 922; (2) Fishermen's Contingency Fund, 50 CFR part 296; (3) Coastal...

  7. The Correlation Between Subjective and Objective Measures of Coded Speech Quality and Intelligibility Following Noise Corruption

    DTIC Science & Technology

    1981-12-01

    VALUES OF EACH BLOCK C TO BE PRINTED. C C ASTORE - 256 VALUE REAL ARRAY USED TO C STORE THE CONVERTED VOLTAGES C FROM ISTORE C C SBLK- STARTING BLOCK...BETWEEN -5.00 C VOLTS AND +5.00 VOLTS. C ~c INTEGER IFILE(13),SBLK,CBLK,ISTORE(256),ST(22), " IBLOCKSJFILE(13),EBLK t :- C REAL ASTORE (256) C C ENTER...CONVERT EACH BLOCK TO BE PRINTED INTO VOLTAGES AND C STORE IN THE ARRAY ASTORE . WRITE ASTORE INTO THE C FILE NAMED BY JFILE C C DO 60 I=1,256 ASTORE (I

  8. First-Principles Study of Superconductivity in Ultra- thin Pb Films

    NASA Astrophysics Data System (ADS)

    Noffsinger, Jesse; Cohen, Marvin L.

    2010-03-01

    Recently, superconductivity in ultrathin layered Pb has been confirmed in samples with as few as two atomic layers [S. Qin, J. Kim, Q. Niu, and C.-K. Shih, Science 2009]. Interestingly, the prototypical strong-coupling superconductor exhibits different Tc's for differing surface reconstructions in samples with only two monolayers. Additionally, Tc is seen to oscillate as the number of atomic layers is increased. Using first principles techniques based on Wannier functions, we analyze the electronic structure, lattice dynamics and electron-phonon coupling for varying thicknesses and surface reconstructions of layered Pb. We discuss results as they relate to superconductivity in the bulk, for which accurate calculations of superconducting properties can be compared to experiment [W. L. McMillan and J.M. Rowell, PRL 1965]. This work was supported by National Science Foundation Grant No. DMR07-05941, the U.S. Department of Energy under Contract No. DE-AC02-05CH11231. Computational resources have been provided by the Lawrencium computational cluster resource provided by the IT Division at the Lawrence Berkeley National Laboratory (Supported by the Director, Office of Science, Office of Basic Energy Sciences, of the U.S. Department of Energy under Contract No. DE-AC02-05CH11231)

  9. Malignant neoplasms of the nasal cavity and paranasal sinuses: a series of 256 patients in Mexico City and Monterrey. Is air pollution the missing link?

    PubMed

    Calderón-Garcidueñas, L; Delgado, R; Calderón-Garcidueñas, A; Meneses, A; Ruiz, L M; De La Garza, J; Acuna, H; Villarreal-Calderón, A; Raab-Traub, N; Devlin, R

    2000-04-01

    Air pollution is a serious health problem in major cities in Mexico. The concentrations of monitored criteria pollutants have been above the US National Ambient Air Quality Standards for the last decade. To determine whether the number of primary malignant nasal and paranasal neoplasms has increased, we surveyed 256 such cases admitted to a major adult oncology hospital located in metropolitan Mexico City (MMC) for the period from 1976-1997 and to a tertiary hospital in Monterrey, an industrial city, for the period from 1993-1998. The clinical histories and histopathologic material were reviewed, and a brief clinical summary was written for each case. In the MMC hospital the number of newly diagnosed nasal and paranasal neoplasms per year for the period from 1976-1986 averaged 5.1, whereas for the next 11 years it increased to 12.5. The maximal increase was observed in 1995-1997, with an average of 20.3 new cases per year (P = 0.0006). The predominant neoplasms in these series were non-Hodgkin's lymphoma, squamous cell carcinoma, melanoma, adenocarcinoma, Schneiderian carcinoma, and nasopharyngeal carcinoma. In the Monterrey hospital a 2-fold increase in the numbers of newly diagnosed nasal and paranasal neoplasms was recorded between 1993 and 1998. The predominant MMC neoplasm in this series, namely nasal T-cell/natural killer cell non-Hodgkin's lymphoma, is potentially Epstein-Barr virus related. Nasal and paranasal malignant neoplasms are generally rare. Environmental causative factors include exposure in industries such as nickel refining, leather, and wood furniture manufacturing. Although epidemiologic studies have not addressed the relationship between outdoor air pollution and sinonasal malignant neoplasms, there is strong evidence for the nasal and paranasal carcinogenic effect of occupational aerosol complex chemical mixtures. General practitioners and ear, nose, and throat physicians working in highly polluted cities should be aware of the clinical

  10. Extending the Advanced Forensic Format to Accommodate Multiple Data Sources, Logical Evidence, Arbitrary Information and Forensic Workflow

    DTIC Science & Technology

    2009-01-01

    objects, and in particular the attribute of SHA256 hash is expressed (but other attributes may also be expressed). Digital signatures have been used in...34a62f06/00000 aff4: sha256 ¼þXf4i..7rPCgo ¼ urn:aff4:34a62f06/00000.idx aff4: sha256 ¼ ptV7xOK6..C7R6Xs ¼ urn:aff4:34a62f06/properties aff4: sha256 ¼ yoZ..YMtk...urn:aff4:34a62f06 aff4: sha256 ¼ udajC5C.BVii7psU ¼ fls-i aff4 ‘‘NY case 1’’ aff4imager -i -o http://ny.wan/evidence2.aff4 \\ -k http://ny.wan/alice.key

  11. LBNL DSD Whole Frog Project

    Science.gov Websites

    500 x 1Byte x 136 images. So each 500 bytes from this dataset represents one scan line of the slice image. For example, using PBM: Get frame one: rawtopgm 256 256 < tomato.data > frame1 Get frames one to four into a single image: rawtopgm 256 1024 < tomato.data >frame1-4 Get frame two (skip

  12. Advancing Cost-Effective Readiness by Improving the Supply Chain Management of Sparse, Intermittently-Demanded Parts

    DTIC Science & Technology

    2015-03-26

    DEMANDED PARTS DISSERTATION Gregory H. Gehret AFIT-ENS-DS-15-M- 256 DEPARTMENT OF THE AIR FORCE AIR UNIVERSITY AIR FORCE INSTITUTE...protection in the United States. AFIT-ENS-DS-15-M- 256 ADVANCING COST-EFFECTIVE READINESS BY IMPROVING THE SUPPLY CHAIN MANAGEMENT OF SPARSE...RELEASE; DISTRIBUTION UNLIMITED. AFIT-ENS-DS-15-M- 256 ADVANCING COST-EFFECTIVE READINESS BY IMPROVING THE SUPPLY CHAIN MANAGEMENT OF SPARSE

  13. 40 CFR Table A-7 to Subpart A of... - Data Elements That Are Inputs to Emission Equations and for Which the Reporting Deadline Is March...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ....116(b) Only annual production by product from each EAF (No CEMS). K 98.116(e)(4) All. K 98.116(e)(5... factor if using Eq. Y-3. Y 98.256(e)(10) Only fraction of carbon in the flare gas contributed by methane... methane in coking gas. Y 98.256(l)(5) Only molar volume conversion factor. Y 98.256(m)(3) Only total...

  14. Structure-guided modification of Rhizomucor miehei lipase for production of structured lipids.

    PubMed

    Zhang, Jun-Hui; Jiang, Yu-Yan; Lin, Ying; Sun, Yu-Fei; Zheng, Sui-Ping; Han, Shuang-Yan

    2013-01-01

    To improve the performance of yeast surface-displayed Rhizomucor miehei lipase (RML) in the production of human milk fat substitute (HMFS), we mutated amino acids in the lipase substrate-binding pocket based on protein hydrophobicity, to improve esterification activity. Five mutants: Asn87Ile, Asn87Ile/Asp91Val, His108Leu/Lys109Ile, Asp256Ile/His257Leu, and His108Leu/Lys109Ile/Asp256Ile/His257Leu were obtained and their hydrolytic and esterification activities were assayed. Using Discovery Studio 3.1 to build models and calculate the binding energy between lipase and substrates, compared to wild-type, the mutant Asp256Ile/His257Leu was found to have significantly lower energy when oleic acid (3.97 KJ/mol decrease) and tripalmitin (7.55 KJ/mol decrease) were substrates. This result was in accordance with the esterification activity of Asp256Ile/His257Leu (2.37-fold of wild-type). The four mutants were also evaluated for the production of HMFS in organic solvent and in a solvent-free system. Asp256Ile/His257Leu had an oleic acid incorporation of 28.27% for catalyzing tripalmitin and oleic acid, and 53.18% for the reaction of palm oil with oleic acid. The efficiency of Asp256Ile/His257Leu was 1.82-fold and 1.65-fold that of the wild-type enzyme for the two reactions. The oleic acid incorporation of Asp256Ile/His257Leu was similar to commercial Lipozyme RM IM for palm oil acidolysis with oleic acid. Yeast surface-displayed RML mutant Asp256Ile/His257Leu is a potential, economically feasible catalyst for the production of structured lipids.

  15. A workflow for multiclass determination of 256 pesticides in essential oils by liquid chromatography tandem mass spectrometry using evaporation and dilution approaches: Application to lavandin, lemon and cypress essential oils.

    PubMed

    Fillatre, Yoann; Rondeau, David; Daguin, Antoine; Communal, Pierre-Yves

    2016-01-01

    This paper describes the determination of 256 multiclass pesticides in cypress and lemon essential oils (EOs) by the way of liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI/MS/MS) analysis using the scheduled selected reaction monitoring mode (sSRM) available on a hybrid quadrupole linear ion trap (QLIT) mass spectrometer. The performance of a sample preparation of lemon and cypress EOs based on dilution or evaporation under nitrogen assisted by a controlled heating were assessed. The best limits of quantification (LOQs) were achieved with the evaporation under nitrogen method giving LOQs≤10µgL(-1) for 91% of the pesticides. In addition the very satisfactory results obtained for recovery, repeatability and linearity showed that for EOs of relatively low evaporation temperature, a sample preparation based on evaporation under nitrogen is well adapted and preferable to dilution. By compiling these results with those previously published by some of us on lavandin EO, we proposed a workflow dedicated to multiresidue determination of pesticides in various EOs by LC-ESI/sSRM. Among the steps involved in this workflow, the protocol related to mass spectrometry proposes an alternative confirmation method to the classical SRM ratio criteria based on a sSRM survey scan followed by an information-dependent acquisition using the sensitive enhanced product ion (EPI) scan to generate MS/MS spectra then compared to a reference. The submitted workflow was applied to the case of lemon EOs samples highlighting for the first time the simultaneous detection of 20 multiclass pesticides in one EO. Some pesticides showed very high concentration levels with amounts greatly exceeding the mgL(-1). Copyright © 2015 Elsevier B.V. All rights reserved.

  16. Intelligence and Electronic Warfare (IEW) Streamlining Project. Volume 3. Reference Documentation (Part 2), B

    DTIC Science & Technology

    1992-09-01

    DoC* A 0" SAF ED P To FS E’F IRA C cons SPDOD ACES OPTPS 0(14 con 0CAC -O-0( Ell 23n Doc AG DOI on @- TS A Of0 Eg D SSO OIPIV PR0C At"C EMSC EN6ICT...except as noted in specific agreements, through 30 Sep 94. (4) Distribute, on a pro rata basis, across all CMFs, those resource changes imposed by...156A (.RD) Sig Sys Maint Tech WOTTC 1 Oct 93 256A 4C-256A Sig Sys Maint Tecn WOTTC I Oct 93 256A 4-11-C32-256A-RC Phase I Sig Sys Maint Tech SWOT -RC

  17. Two novel compound heterozygous mutations in the BCKDHB gene that cause the intermittent form of maple syrup urine disease.

    PubMed

    Guo, Yi; Liming, Liu; Jiang, Li

    2015-12-01

    Intermittent maple syrup urine disease (MSUD) is a potentially life-threatening metabolic disorder caused by a deficiency of branched chain α-ketoacid dehydrogenase (BCKD) complex. In contrast to classic MSUD, children with the intermittent form usually have an atypical clinical manifestation. Here, we describe the presenting symptoms and clinical course of a Chinese boy with intermittent MSUD. Mutation analysis identified two previously unreported mutations in exon 7 of the BCKDHB gene: c.767A > G (p.Y256C) and c.768C > G (p.Y256X); the parents were each heterozygous for one of these mutations. In silico analysis predicted Y256C probably affects protein structure; Y256X leads to a premature stop codon. This case demonstrates intermittent MSUD should be suspected in cases with symptoms of recurrent encephalopathy, especially ataxia or marked drowsiness, which usually present after the neonatal period and in conjunction with infection. symmetrical basal ganglia damage but normal myelination in the posterior limb will assist differential diagnosis; alloisoleucine is a useful diagnostic marker and mutation analysis may be of prognostic value. These novel mutations Y256C and Y256X result in the clinical manifestation of a variant form of MSUD, expanding the mutation spectrum of this disease.

  18. LinoSPAD: a time-resolved 256×1 CMOS SPAD line sensor system featuring 64 FPGA-based TDC channels running at up to 8.5 giga-events per second

    NASA Astrophysics Data System (ADS)

    Burri, Samuel; Homulle, Harald; Bruschini, Claudio; Charbon, Edoardo

    2016-04-01

    LinoSPAD is a reconfigurable camera sensor with a 256×1 CMOS SPAD (single-photon avalanche diode) pixel array connected to a low cost Xilinx Spartan 6 FPGA. The LinoSPAD sensor's line of pixels has a pitch of 24 μm and 40% fill factor. The FPGA implements an array of 64 TDCs and histogram engines capable of processing up to 8.5 giga-photons per second. The LinoSPAD sensor measures 1.68 mm×6.8 mm and each pixel has a direct digital output to connect to the FPGA. The chip is bonded on a carrier PCB to connect to the FPGA motherboard. 64 carry chain based TDCs sampled at 400 MHz can generate a timestamp every 7.5 ns with a mean time resolution below 25 ps per code. The 64 histogram engines provide time-of-arrival histograms covering up to 50 ns. An alternative mode allows the readout of 28 bit timestamps which have a range of up to 4.5 ms. Since the FPGA TDCs have considerable non-linearity we implemented a correction module capable of increasing histogram linearity at real-time. The TDC array is interfaced to a computer using a super-speed USB3 link to transfer over 150k histograms per second for the 12.5 ns reference period used in our characterization. After characterization and subsequent programming of the post-processing we measure an instrument response histogram shorter than 100 ps FWHM using a strong laser pulse with 50 ps FWHM. A timing resolution that when combined with the high fill factor makes the sensor well suited for a wide variety of applications from fluorescence lifetime microscopy over Raman spectroscopy to 3D time-of-flight.

  19. The Utility of fMRI for Assessing and Predicting Individual Differences in Fatigue Vulnerability

    DTIC Science & Technology

    2010-06-15

    field of view (FOV) = 25.6 cm, image matrix = 256 x 256. Next, a set of T1-weighted axial low -resolution anatomical images encompassing the whole...wide range of central nervous system disorders and medication effects ( Lowe & Rabbitt, 1998; Randall, Fleck, Shneerson & File, 2004). These tests are...fusiform gyrus (Figure 5E); 6) Brodmann area 19 (Figure 5F); and 7) the entire cerebellum (Figure 5G ). Figure 5. Axial (top row) and sagittal

  20. Processing of A New Digital Orthoimage Map of The Martian Western Hemisphere Using Data Obtained From The Mars Orbiter Camera At A Resolution of 256 Pixel/deg

    NASA Astrophysics Data System (ADS)

    Wählisch, M.; Niedermaier, G.; van Gasselt, S.; Scholten, F.; Wewel, F.; Roatsch, T.; Matz, K.-D.; Jaumann, R.

    We present a new digital orthoimage map of Mars using data obtained from the CCD line scanner Mars Orbiter Camera (MOC) of the Mars Global Surveyor Mis- sion (MGS) [1,2]. The map covers the Mars surface from 0 to 180 West and from 60 South to 60 North with the MDIM2 resolution of 256 pixel/degree and size. Image data processing has been performed using multiple programs, developed by DLR, Technical University of Berlin [3], JPL, and the USGS. 4,339 Context and 183 Geodesy images [2] were included. After radiometric corrections, the images were Mars referenced [4], geometrically corrected [5] and orthoprojected using a global Martian Digital Terrain Model (DTM) with a resolution of 64 pixel/degree, developed at DLR and based on MGS Mars Orbiter Laser Altimeter (MOLA) data [6]. To elim- inate major differences in brightness between the individual images of the mosaics, high- and low-pass filter processing techniques were applied for each image. After filtering, the images were mosaicked without registering or using block adjustment techniques in order to improve the geometric quality. It turns out that the accuracy of the navigation data has such a good quality that the orthoimages fit very well to each other. When merging the MOC mosaic with the MOLA data using IHS- trans- formation, we recognized very good correspondence between these two datasets. We create a topographic image map of the Coprates region (MC­18) adding contour lines derived from the global DTM to the mosaic. These maps are used for geological and morphological interpretations in order to review and improve our current Viking-based knowledge about the Martian surface. References: [1] www.mssss.com, [2] Caplinger, M. and M. Malin, "The Mars Or- biter Camera Geodesy Campaign, JGR, in press, [3] Scholten, F., Vol XXXI, Part B2, Wien 1996, p.351-356, [4] naïf.jpl.nasa.gov, [5] R.L.Kirk. et al. (2001), "Geometric Calibration of the Mars Orbiter Cameras and Coalignment with Mars Orbiter Laser Altimeter