Using biochemical and isotope geochemistry to understand the environmental and public health implications of lead pollution in the lower Guadiana River, Iberia: a freshwater bivalve study.

PubMed

Company, R; Serafim, A; Lopes, B; Cravo, A; Shepherd, T J; Pearson, G; Bebianno, M J

2008-11-01

Lead is a natural component of aquatic ecosystems with no known biological role and is highly toxic. Its toxicity stems from its ability to mimic biologically important metals and to produce membrane damage through lipid peroxidation (LPO). Most lead poisoning symptoms are thought to occur by interfering with an essential enzyme, delta-aminolevulinic acid dehydratase (ALAD), the activity of which is markedly inhibited by lead. The purpose of this work was to study the levels and effects of lead pollution (responses of ALAD and oxidative stress biomarker LPO) in the freshwater bivalve Corbicula fluminea along the lower Guadiana River (Portugal and Spain); a major river system impacted by historic mining pollution and more recent anthropogenic inputs. The results show that the enzymatic activity of ALAD is negatively correlated with the total Pb concentration of the whole tissue suggesting that ALAD has considerable potential as a biomarker of lead exposure in C. fluminea. To identify the sources of lead to which bivalves have been exposed, high precision (206)Pb/(204)Pb, (207)Pb/(204)Pb, (208)Pb/(204)/Pb ratios for C. fluminea confirm that historical mining activities in the Iberian Pyrite Belt are the dominant source of lead pollution in the lower Guadiana River. The isotope patterns however exhibit marked seasonal and geographic variation in response to rainfall and river water management. Locally, other anthropogenic sources of lead have been detected in C. fluminea close to population centres, thus adding to its versatility as a freshwater bio-indicator. Overall, the study highlights the value of natural ecosystems as monitors of water quality and their importance for public health assessment and surveillance.

Some Pb and Sr isotopic measurements on eclogites from the Roberts Victor mine, South Africa

USGS Publications Warehouse

Manton, W.I.; Tatsumoto, M.

1971-01-01

Five nodules of eclogite, one nodule of garnet peridotite and one sample of kimberlite from the Roberts Victor mine were analyzed for concentrations of U, Th, Pb, Rb and Sr and isotopic compositions of Pb and Sr. In the eclogites, U content ranges from 0.09 to 0.26 ppm, Th from 0.35 to 1.1 ppm, Pb from 0.79 to 5.5 ppm, Rb from 2.1 to 28 ppm and Sr from 133 to 346 ppm; 206Pb/204Pb ratios range from 14.8 to 18.5, 207Pb/204Pb from 14.9 to 15.7, 208Pb/204Pb from 35.2 to 38.5. The garnet peridotite contains 0.22 ppm U, 0.97 ppm Th, 1.05 ppm Pb, 6.9 ppm Rb and 108 ppm Sr and the kimberlite contains 2.5 ppm U, 30 ppm Th, 37 ppm Pb, 113 ppm Rb and 2040 ppm Sr. The lead in the eclogites has two components, a lead pyroextractable at 1100-1200?? and a non-pyroextractable residual lead. In three of the eclogites, which are to some extent altered, a proportion of the pyroextractable lead may be contaminating lead from the kimberlite, but an altered kyanite eclogite does not appear to be contaminated by this same kimberlite. The pyroextractable lead from a less altered eclogite contains a much larger proportion of 206Pb. Compositions calculated for the residual leads vary greatly. In many of the pyroextraction runs the primary eclogitic phases disappeared and the new phases plagioclase, clinopyroxene and a magnetic iron compound were formed. Why part of the lead should have been retained by these new phases is not understood. ?? 1971.

Isotope-ratio measurements of lead in NIST standard reference materials by multiple-collector inductively coupled plasma mass spectrometry.

PubMed

Platzner, I; Ehrlich, S; Halicz, L

2001-07-01

The capability of a second-generation Nu Instruments multiple collector inductively coupled plasma mass spectrometer (MC-ICP-MS) has been evaluated for precise and accurate isotope-ratio determinations of lead. Essentially the mass spectrometer is a double-focusing instrument of Nier-Johnson analyzer geometry equipped with a newly designed variable-dispersion ion optical device, enabling the measured ion beams to be focused into a fixed array of Faraday collectors and an ion-counting assembly. NIST SRM Pb 981, 982, and 983 isotopic standards were used. Addition of thallium to the lead standards and subsequent simultaneous measurement of the thallium and lead isotopes enabled correction for mass discrimination, by use of the exponential correction law and 205Tl/203Tl = 2.3875. Six measurements of SRM Pb-982 furnished the results 206Pb/204Pb = 36.7326(68), 207Pb/204Pb = 17.1543(30), 208Pb/204Pb = 36.7249(69), 207Pb/206Pb = 0.46700(1), and 208Pb/206Pb = 0.99979(2); the NIST-certified values were 36.738(37), 17.159(25), 36.744(50), 0.46707(20), and 1.00016(36), respectively. Direct isotope lead analysis in silicates can be performed without any chemical separation. NIST SRM 610 glass was dissolved and introduced into the MC-ICP-MS by means of a micro concentric nebulizer. The ratios observed were in excellent agreement with previously reported data obtained by TIMS and laser ablation MC-ICP-MS, despite the high Ca/Pb concentration ratio (200/1) and the presence of many other elements at levels comparable with that of lead. Approximately 0.2 microg lead are sufficient for isotope analysis with ratio uncertainties between 240 and 530 ppm.

Oceanic Pb-isotopic sources of proterozoic and paleozoic volcanogenic massive sulfide deposits on Prince of Wales Island and vicinity, southeastern Alaska

USGS Publications Warehouse

Ayuso, Robert A.; Karl, Susan M.; Slack, John F.; Haeussler, Peter J.; Bittenbender, Peter E.; Wandless, Gregory A.; Colvin, Anna

2005-01-01

Volcanogenic massive sulfide (VMS) deposits on Prince of Wales Island and vicinity in southeastern Alaska are associated with Late Proterozoic through Cambrian volcanosedimentary rocks of the Wales Group and with Ordovician through Early Silurian felsic volcanic rocks of the Moira Sound unit (new informal name). The massive sulfide deposits in the Wales Group include the Big Harbor, Copper City, Corbin, Keete Inlet, Khayyam, Ruby Tuesday, and Stumble-On deposits, and those in the Moira Sound unit include the Barrier Islands, Moira Copper, Niblack, and Nichols Bay deposits. Pb-isotopic signatures were determined on sulfide minerals (galena, pyrite, chalcopyrite, pyrrhotite, and sphalerite) to constrain metal sources of the massive sulfides and for comparison with data for other deposits in the region. Except for the Ruby Tuesday deposit, galena is relatively rare in most of these deposits. Pb-isotopic signatures distinguish the mainly Cu+Zn±Ag±Au massive sulfide deposits in the Wales Group from the Zn+Cu±Ag±Au massive sulfide deposits in the Moira Sound unit. Among the older group of deposits, the Khayyam deposit has the widest variation in Pb-isotopic ratios (206Pb/204Pb=17.169–18.021, 207Pb/204Pb=15.341–15.499, 208Pb/204Pb=36.546–37.817); data for the other massive sulfide deposits in the Wales Group overlap the isotopic variations in the Khayyam deposit. Pb-isotopic ratios for both groups of deposits are lower than those on the average crustal Pbevolution curve (µ=9.74), attesting to a large mantle influence in the Pb source. All the deposits show no evidence for Pb evolution primarily in the upper or lower continental crust. Samples from the younger group of deposits have scattered Pb-isotopic compositions and plot as a broad band on uranogenic and thorogenic Pb diagrams. Data for these deposits overlap the trend for massive sulfide deposits in the Wales Group but extend to significantly more radiogenic Pb-isotopic values. Pb-isotopic ratios of samples from the massive sulfide deposits in the Moira Sound unit plot on a different trend (206Pb/204Pb=17.375–19.418, 207Pb/204Pb=15.361–15.519, 208Pb/204Pb=36.856–37.241) from the steep slope defined by the massive sulfide deposits in the Wales Group. In comparison, the Pb-isotopic ratios of Devonian polymetallic (Pb-Zn-Au-Ag) quartz-sulfide veins vary widely ( 206Pb/204Pb=18.339–18.946, 207Pb/204Pb=15.447–15.561, 208Pb/204Pb=37.358–38.354), straddling the slope defined by the massive sulfide deposits in the Moira Sound unit. The general decrease in 207Pb/204Pb ratio in these deposits, relative to the average crustal Pb-evolution curve, suggests that the most likely lead sources were those associated with oceanic volcanic rocks. The massive sulfide deposits in the Wales Group may have resided within an intraoceanic tectonic setting where the mantle was the predominant contributor of metals. Some contribution from reworked arc material or recycled older, hydrothermally altered oceanic crust (including pelagic sediment) is also possible. Lead sources of the massive sulfide deposits in the Moira Sound unit also included an older source region, possibly a Late Proterozoic or Cambrian volcanosedimentary sequence and the massive sulfide deposits in the Wales Group. Preliminary regional comparison of the Pb-isotopic data indicates that the Greens Creek (Admiralty Island, Alaska) and Windy Craggy (northern British Columbia) deposits probably did not share a common lead source with the VMS deposits on Prince of Wales Island. Other sulfide occurrences on Admiralty Island are also more radiogenic than those on Prince of Wales Island. Large differences in 207Pb/204Pb ratio suggest that the lead in the VMS deposits in different parts of the Alexander terrane evolved from sources with heterogeneous U/Pb ratios, resulting from mixing of mantle and crustal components. 

Anthropogenic and natural lead isotopes in Fe-hydroxides and Fe-sulphates in a watershed associated with arsenic-enriched groundwater, Maine, USA

USGS Publications Warehouse

Ayuso, Robert A.; Foley, Nora K.

2008-01-01

A survey of the natural and anthropogenic sources of lead contributing to secondary minerals in sulphidic schists associated with arsenic-enriched groundwater in Coastal Maine shows that the most likely source is natural Pb, particularly from coexisting sulphide minerals. The secondary minerals also reflect notable contributions from anthropogenic Pb. The Pb isotopes establish pathways by which Pb, and by inference As, could have been transported from As-bearing minerals (arsenian pyrite, arsenopyrite, lollingite, orpiment, arsenic oxide and others), via sulphide oxidation or carbonation reactions into multiple generations of secondary minerals (goethite, hematite, jarosite, natrojarosite and others). Lead isotopic compositions of the sulphides and secondary minerals determined by thermal ionization mass spectrometry (n=53) range widely. Lead and As contents of the sulphides and secondary minerals overlap, and are generally positively correlated. Pyrite, the dominant sulphide in sulphidic schists associated with As-enriched groundwater in Coastal Maine, has values of 206Pb/204Pb from 18.186 to 18.391, 207Pb/204Pb from 15.617 to 15.657, 208Pb/204Pb from 38.052 to 38.210, 206Pb/207Pb from c. 1.1625 to 1.1760 and 208Pb/207Pb from c. 2.4276 to 2.4394. Mixtures of Fe-hydroxide and oxide minerals (predominantly goethite and hematite) and secondary Fe-sulphate minerals (jarosite, natrojarosite, rozenite and melanterite) in the sulphidic schists have overlapping but generally higher values of 206Pb/204Pb from 18.495 to 19.747 (one sample at 21.495), 207Pb/204Pb from 15.595 to 15.722 (one sample at 15.839), 208Pb/204Pb from 38.186 to 39.162,206Pb/207Pb from c.1.1860 to 1.2575 (one sample at 1.3855) and 208Pb/207Pb from c. 2.4441 to 2.4865 than the sulphides. Sulphides from Zn-Pb metal mines are somewhat less radiogenic than sulphides from the schists. Other sulphides (mostly pyrite) associated with pegmatites and granitic rocks are heterogeneous and more radiogenic than the pyrite-rich sulphidic schists. Sulphides from other regional bedrock units also have heterogeneous isotope values. Lead isotopic compositions of the sulphides from the sulphidic schists and coexisting Fe-oxides and Fe-sulphates produced by weathering and alteration overlap, but the secondary minerals extend toward more radiogenic values that broadly indicate the addition of Pb from anthropogenic origin. As a component of Pb from extensively used arsenical pesticides may also be present in the secondary minerals, the range in Pb isotope values is consistent with multiple sources: natural Pb from the schists and anthropogenic Pb (industrial and possibly from agricultural activities). Contributions from past mining activities or from other bedrock sources are not implicated.

Lead isotopic evidence for mixed sources of Proterozoic granites and pegmatites, Black Hills, South Dakota, USA

NASA Astrophysics Data System (ADS)

Krogstad, Eirik J.; Walker, Richard J.; Nabelek, Peter I.; Russ-Nabelek, Carol

1993-10-01

The lead isotopic compositions of K-feldspars separated from the ca. 1700 Ma Harney Peak Granite complex and spatially associated granitic pegmatites indicate that these rocks were derived from at least two sources. It has been reported previously that the core of the Harney Peak Granite complex is dominated by relatively lower/ gd18O (avg. 11.5 %.) granites, whereas higher / gd18O (avg. 13.2%.) granites occur around the periphery of the complex. The higher δ 18O granites and one simple pegmatite have low values of 207Pb /204Pb for their 206Pb /204Pb Thus, they likely were derived from a source with a short crustal residence time. This source may have been the pelitic schists into which the Harney Peak Granite complex and pegmatites were intruded. Feldspars from granites with lower / gd18O values have significantly higher 207Pb /204Pb for their 206Pb /204Pb . The data define a linear array with a slope equivalent to an age of ca. 2.6 Ga with t 2 defined to be 1.7 Ga. Such a slope could represent a mixing array or a secondary isochron for the source. These low δ18O granites could have been derived from a source with a high U/ Pb and with a crustal residence beginning before the Proterozoic. The source (s) of these granites may have been a sediment derived from late Archean continental crust. The highly evolved Tin Mountain pegmatite has lead isotopic systematics intermediate between those of the two granite groups, suggesting either a mixed source or contamination. Two late Archean granites, the Little Elk Granite and the Bear Mountain Granite, had precursors with high U/Pb and low Th/U histories. The Th/U history of the Bear Mountain Granite is too low for this rock to have been an important component of the source of the Proterozoic granites. However, crustal rocks with lead isotopic compositions similar to those of the Little Elk Granite were an important source of lead for some of the Proterozoic granitic rocks.

U-Th-Pb and Rb-Sr systematics of Allende and U-Th-Pb systematics of Orgueil

USGS Publications Warehouse

Tatsumoto, M.; Unruh, D.M.; Desborough, G.A.

1976-01-01

U-Th-Pb systematics study of Allende inclusions showed that U, Th and Sr concentrations in Ca, Al (pyroxene)-rich chondrules and white and pinkish-white aggregate separates of Allende are five to ten times higher than those of the matrix, whereas Mg (olivine)-rich chondrules have U and Th concentrations about twice as high as the matrix. Th concentrations are extremely high in white aggregates and in pinkish-white (spinel-rich) aggregates while U and Sr concentrations in white aggregates are more than twice as high as those in pinkish-white aggregates. Large enrichment of these refractory elements in the white aggregates indicates that they contain high-temperature condensates from the solar nebula. The Pb concentrations in the inclusions are less than half of those in the whole rock and matrix, indicating that the matrix is a lower-temperature condensate. The isotopic composition of lead in the matrix is less radiogenic than that of the whole meteorite, whereas lead in Ca- and Al-rich chondrules and aggregates is extremely radiogenic. The 206Pb/204Pb ratio reaches as high as 55.9 in a white aggregate separate. The lead of Mg-rich chondrules is moderately radiogenic and the 206Pb/204Pb ratio ranges from 18 to 26. A striking linear relationship exists among leads in the chondrules, aggregates and matrix on the 207Pb/204Pb vs 204Pb/204Pb plot. The slope of the best fit line is 0.6188 ?? 0.0016, yielding an isochron age of 4553 ?? 4 m.y. The regression line passes through primordial lead values obtained from Canyon Diablo troilite. The data, when corrected for Canyon Diablo troilite Pb and plotted on a U-Pb concordia diagram, show that the pink and white aggregates and the Ca-Al-rich and Mg-rich inclusions have excess Pb and define a chord which intersects the concordia curve at 4548 ?? 25 m.y. and 107 ?? 70 m.y. The intercepts might correspond to the agglomeration age of the meteorite and a time of probably later disturbance, respectively. The matrix and some chondrules which contain less radiogenic lead did, however, not fit on the chord. The Rb-Sr data of Allende did not define an isochron suggesting that the Rb-Sr system was also disturbed by a later event, as suggested by the U-Pb concordia data. The lowest observed 87Sr/86Sr ratio in Allende inclusions is similar to the initial ratio of the Angra dos Reis achondrite (Papanastassiou, Thesis, 1970). The initial Pb isotopic composition of Orgueil calculated by a single-stage evolution model is more radiogenic than that of Canyon Diablo troilite. To reconcile the U-Pb data of Orgueil and Allende, we propose that the initial lead isotopic composition of the carbonaceous chondrites was slightly different from that of Canyon Diablo troilite Pb. ?? 1976.

Cooperative multi-targeting of signaling networks by angiomiR-204 inhibits vasculogenic mimicry in breast cancer cells.

PubMed

Salinas-Vera, Yarely M; Marchat, Laurence A; García-Vázquez, Raúl; González de la Rosa, Claudia Haydée; Castañeda-Saucedo, Eduardo; Tito, Napoleón Navarro; Flores, Carlos Palma; Pérez-Plasencia, Carlos; Cruz-Colin, José L; Carlos-Reyes, Ángeles; López-González, José Sullivan; Álvarez-Sánchez, María Elizbeth; López-Camarillo, César

2018-06-06

RNA-based multi-target therapies focused in the blocking of signaling pathways represent an attractive approach in cancer. Here, we uncovered a miR-204 cooperative targeting of multiple signaling transducers involved in vasculogenic mimicry (VM). Our data showed that invasive triple negative MDA-MB-231 and Hs-578T breast cancer cells, but not poorly invasive MCF-7 cells, efficiently undergoes matrix-associated VM under hypoxia. Ectopic restoration of miR-204 in MDA-MB-231 cells leads to a potent inhibition of VM and reduction of number of branch points and patterned 3D channels. Further analysis of activation state of multiple signaling pathways using Phosphorylation Antibody Arrays revealed that miR-204 reduced the expression and phosphorylation levels of 13 proteins involved in PI3K/AKT, RAF1/MAPK, VEGF, and FAK/SRC signaling. In agreement with phospho-proteomic profiling, VM was impaired following pharmacological administration of PI3K and SRC inhibitors. Mechanistic studies confirmed that miR-204 exerts a negative post-transcriptional regulation of PI3K-α and c-SRC proto-oncogenes. Moreover, overall survival analysis of a large cohort of breast cancer patients indicates that low miR-204 and high FAK/SRC levels were associated with worst outcomes. In conclusion, our study provides novel lines of evidence indicating that miR-204 may exerts a fine-tuning regulation of the synergistic transduction of PI3K/AKT/FAK mediators critical in VM formation. Copyright © 2018 Elsevier B.V. All rights reserved.

Uranium-lead isotope systematics of Mars inferred from the basaltic shergottite QUE 94201

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gaffney, A M; Borg, L E; Connelly, J N

2006-12-22

Uranium-lead ratios (commonly represented as {sup 238}U/{sup 204}Pb = {mu}) calculated for the sources of martian basalts preserve a record of petrogenetic processes that operated during early planetary differentiation and formation of martian geochemical reservoirs. To better define the range of {mu} values represented by the source regions of martian basalts, we completed U-Pb elemental and isotopic analyses on whole rock, mineral and leachate fractions from the martian meteorite Queen Alexandra Range 94201 (QUE 94201). The whole rock and silicate mineral fractions have unradiogenic Pb isotopic compositions that define a narrow range ({sup 206}Pb/{sup 204}Pb = 11.16-11.61). In contrast, themore » Pb isotopic compositions of weak HCl leachates are more variable and radiogenic. The intersection of the QUE 94201 data array with terrestrial Pb in {sup 206}Pb/{sup 204}Pb-{sup 207}Pb/{sup 204}Pb-{sup 208}Pb/{sup 204}Pb compositional space is consistent with varying amounts of terrestrial contamination in these fractions. We calculate that only 1-7% contamination is present in the purified silicate mineral and whole rock fractions, whereas the HCl leachates contain up to 86% terrestrial contamination. Despite the contamination, we are able to use the U-Pb data to determine the initial {sup 206}Pb/{sup 204}Pb of QUE 94201 (11.086 {+-} 0.008) and calculate the {mu} value of the QUE 94201 mantle source to be 1.823 {+-} 0.008. This is the lowest {mu} value calculated for any martian basalt source, and, when compared to the highest values determined for martian basalt sources, indicates that {mu} values in martian source reservoirs vary by at least 100%. The range of source {mu} values further indicates that the {mu} value of bulk silicate Mars is approximately three. The amount of variation in the {mu} values of the mantle sources ({mu} {approx} 2-4) is greater than can be explained by igneous processes involving silicate phases alone. We suggest the possibility that a small amount of sulfide crystallization may generate large extents of U-Pb fractionation during formation of the mantle sources of martian basalts.« less

The 17D-204 and 17DD yellow fever vaccines: an overview of major similarities and subtle differences.

PubMed

Ferreira, Clarissa de Castro; Campi-Azevedo, Ana Carolina; Peruhype-Magalhāes, Vanessa; Costa-Pereira, Christiane; Albuquerque, Cleandro Pires de; Muniz, Luciana Feitosa; Yokoy de Souza, Talita; Oliveira, Ana Cristina Vanderley; Martins-Filho, Olindo Assis; da Mota, Licia Maria Henrique

2018-01-01

The yellow fever vaccine is a live attenuated virus vaccine that is considered one of the most efficient vaccines produced to date. The original 17D strain generated the substrains 17D-204 and 17DD, which are used for the current production of vaccines against yellow fever. The 17D-204 and 17DD substrains present subtle differences in their nucleotide compositions, which can potentially lead to variations in immunogenicity and reactogenicity. We will address the main changes in the immune responses induced by the 17D-204 and 17DD yellow fever vaccines and report similarities and differences between these vaccines in cellular and humoral immunity . This is a relevant issue in view of the re-emergence of yellow fever in Uganda in 2016 and in Brazil in the beginning of 2017. Areas covered: This article will be divided into 8 sections that will analyze the innate immune response, adaptive immune response, humoral response, production of cytokines, immunity in children, immunity in the elderly, gene expression and adverse reactions. Expert commentary: The 17D-204 and 17DD yellow fever vaccines present similar immunogenicity, with strong activation of the cellular and humoral immune responses. Additionally, both vaccines have similar adverse effects, which are mostly mild and thus are considered safe.

Identifying sources of Pb pollution in urban soils by means of MC-ICP-MS and TOF-SIMS.

PubMed

Rodríguez-Seijo, Andrés; Arenas-Lago, Daniel; Andrade, María Luisa; Vega, Flora A

2015-05-01

Lead pollution was evaluated in 17 urban soils from parks and gardens in the city of Vigo (NW Spain). The Pb isotope ratios ((207)Pb/(206)Pb, (208)Pb/(204)Pb, (206)Pb/(204)Pb and (208)Pb/(206)Pb) were determined after being measured by MC-ICP-MS. The association of the isotopes ((204)Pb, (206)Pb, (207)Pb and (208)Pb) with the different components of the soil was studied using TOF-SIMS. The isotopic ranges obtained for the samples were between 1.116 and 1.203 ((206)Pb/(207)Pb), 2.044-2.143 ((208)Pb/(206)Pb), 37.206-38.608 ((208)Pb/(204)Pb), 15.5482-15.6569 ((207)Pb/(204)Pb) and 17.357-18.826 ((206)Pb/(204)Pb). The application of the three-end-member model indicates that the Pb derived from petrol is the main source of Pb in the soils (43.51% on average), followed by natural or geogenic Pb (39.12%) and industrial emissions (17.37%). The emissions derived from coal combustion do not appear to influence the content of Pb in the soil. TOF-SIMS images show that the Pb mainly interacts with organic matter. This technique contributes to the understanding of the association of anthropogenic Pb with the components of the soil, as well as the particle size of these associations, thus allowing the possible sources of Pb to be identified.

Characterization of a Novel BCHE “Silent” Allele: Point Mutation (p.Val204Asp) Causes Loss of Activity and Prolonged Apnea with Suxamethonium

PubMed Central

Delacour, Herve; Lushchekina, Sofya; Mabboux, Isabelle; Bousquet, Aurore; Ceppa, Franck; Schopfer, Lawrence M.; Lockridge, Oksana; Masson, Patrick

2014-01-01

Butyrylcholinesterase deficiency is characterized by prolonged apnea after the use of muscle relaxants (suxamethonium or mivacurium) in patients who have mutations in the BCHE gene. Here, we report a case of prolonged neuromuscular block after administration of suxamethonium leading to the discovery of a novel BCHE variant (c.695T>A, p.Val204Asp). Inhibition studies, kinetic analysis and molecular dynamics were undertaken to understand how this mutation disrupts the catalytic triad and determines a “silent” phenotype. Low activity of patient plasma butyrylcholinesterase with butyrylthiocholine (BTC) and benzoylcholine, and values of dibucaine and fluoride numbers fit with heterozygous atypical silent genotype. Electrophoretic analysis of plasma BChE of the proband and his mother showed that patient has a reduced amount of tetrameric enzyme in plasma and that minor fast-moving BChE components: monomer, dimer, and monomer-albumin conjugate are missing. Kinetic analysis showed that the p.Val204Asp/p.Asp70Gly-p.Ala539Thr BChE displays a pure Michaelian behavior with BTC as the substrate. Both catalytic parameters Km = 265 µM for BTC, two times higher than that of the atypical enzyme, and a low Vmax are consistent with the absence of activity against suxamethonium. Molecular dynamic (MD) simulations showed that the overall effect of the mutation p.Val204Asp is disruption of hydrogen bonding between Gln223 and Glu441, leading Ser198 and His438 to move away from each other with subsequent disruption of the catalytic triad functionality regardless of the type of substrate. MD also showed that the enzyme volume is increased, suggesting a pre-denaturation state. This fits with the reduced concentration of p.Ala204Asp/p.Asp70Gly-p.Ala539Thr tetrameric enzyme in the plasma and non-detectable fast moving-bands on electrophoresis gels. PMID:25054547

Mutational activation of a Galphai causes uncontrolled proliferation of aerial hyphae and increased sensitivity to heat and oxidative stress in Neurospora crassa.

PubMed Central

Yang, Q; Borkovich, K A

1999-01-01

Heterotrimeric G proteins, consisting of alpha, beta, and gamma subunits, transduce environmental signals through coupling to plasma membrane-localized receptors. We previously reported that the filamentous fungus Neurospora crassa possesses a Galpha protein, GNA-1, that is a member of the Galphai superfamily. Deletion of gna-1 leads to defects in apical extension, differentiation of asexual spores, sensitivity to hyperosmotic media, and female fertility. In addition, Deltagna-1 strains have lower intracellular cAMP levels under conditions that promote morphological abnormalities. To further define the function of GNA-1 in signal transduction in N. crassa, we examined properties of strains with mutationally activated gna-1 alleles (R178C or Q204L) as the only source of GNA-1 protein. These mutations are predicted to inhibit the GTPase activity of GNA-1 and lead to constitutive signaling. In the sexual cycle, gna-1(R178C) and gna-1(Q204L) strains are female-fertile, but produce fewer and larger perithecia than wild type. During asexual development, gna-1(R178C) and gna-1(Q204L) strains elaborate abundant, long aerial hyphae, produce less conidia, and possess lower levels of carotenoid pigments in comparison to wild-type controls. Furthermore, gna-1(R178C) and gna-1(Q204L) strains are more sensitive to heat shock and exposure to hydrogen peroxide than wild-type strains, while Deltagna-1 mutants are more resistant. In contrast to Deltagna-1 mutants, gna-1(R178C) and gna-1(Q204L) strains have higher steady-state levels of cAMP than wild type. The results suggest that GNA-1 possesses several Gbetagamma-independent functions in N. crassa. We propose that GNA-1 mediates signal transduction pathway(s) that regulate aerial hyphae development and sensitivity to heat and oxidative stresses, possibly through modulation of cAMP levels. PMID:9872952

Kinetic analysis of lead metabolism in healthy humans

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rabinowitz, M.B.; Wetherill, G.W.; Kopple, J.D.

The steady state kinetics of lead metabolism were studied in five healthy men with stable isotope tracers. Subjects lived in a metabolic unit and ate constant low lead diets. Their intake was supplemented each day with 79 to 204 ..mu..g of enriched lead-204 as nitrate which was ingested with meals for 1 to 124 days. The concentration and isotopic composition of lead was determined serially in blood, urine, feces, and diet and less commonly in hair, nails, sweat, bone, and alimentary tract secretions by isotopic dilution, mass spectrometric analysis. The data suggest a three-compartmental model for lead metabolism. The firstmore » compartment encompasses blood and is 1.5 to 2.2 times larger than the blood mass. It contains approximately 1.7 to 2.0 mg of lead and has a mean life of 35 days. This pool is in direct communication with ingested lead, urinary lead, and pools two and three. The second compartment is largely composed of soft tissue, contains about 0.3 to 0.9 mg of lead, and has a mean life of approximately 40 days. This pool gives rise to lead in hair, nails, sweat, and salivary, gastric, pancreatic, and biliary secretions. Pool three resides primarily in the skeleton, contains the vast quantity of body lead, and has a very slow mean life. Bones appear to differ in their rates of lead turnover. Within the relatively small changes in blood lead observed in the present study, the transfer coefficients between the pools remained constant.« less

Pb isotope geochemistry of Piton de la Fournaise historical lavas

NASA Astrophysics Data System (ADS)

Vlastélic, Ivan; Deniel, Catherine; Bosq, Chantal; Télouk, Philippe; Boivin, Pierre; Bachèlery, Patrick; Famin, Vincent; Staudacher, Thomas

2009-07-01

Variations of Pb isotopes in historical lavas (1927-2007) from Piton de la Fournaise are investigated based on new (116 samples) and published (127 samples) data. Lead isotopic signal exhibits smooth fluctuations (18.87 < 206Pb/ 204Pb < 18.94) on which superimpose unradiogenic spikes ( 206Pb/ 204Pb down to 18.70). Lead isotopes are decoupled from 87Sr/ 86Sr and 143Nd/ 144Nd, which display small and barely significant variations, respectively. No significant change of Pb isotope composition occurred during the longest (> 3 years) periods of inactivity of the volcano (1939-1942, 1966-1972, 1992-1998), supporting previous inferences that Pb isotopic variations occur mostly during and not between eruptions. Intermediate compositions (18.904 < 206Pb/ 204Pb < 18.917) bracket the longest periods of quiescence. In this respect, the highly frequent occurrence of an intermediate composition (18.90 < 206Pb/ 204Pb < 18.91), which clearly defines an isotopic baseline during the most recent densely sampled period (1975-2007), either suggests direct sampling of plume melts or sampling of a voluminous magma reservoir that buffers Pb isotopic composition. Deviations from this prevalent composition occurred during well-defined time periods, namely 1977-1986 (radiogenic signature), 1986-1990 and 1998-2005 (unradiogenic signatures). The three periods display a progressive isotopic drift ending by a rapid return (mostly during a single eruption) to the isotopic baseline. The isotopic gradients could reflect progressive emptying of small magma reservoirs or magma conduits, which are expected to be more sensitive to wall-rock interactions than the main magma chamber. These gradients provide a lower bound ranging from 0.1 to 0.17 km 3 for the size of the shallow magma storage system. The isotopic shifts (March 1986, January 1990 and February 2005) are interpreted as refilling the plumbing system with deep melts that have not interacted with crustal components. The volume of magma erupted between the two major refilling events of March 1986 and February 2005 (0.28 km 3) could provide a realistic estimate of the magma reservoir size. Unradiogenic anomalies appear to be linked, more or less directly, to the eruption of olivine-rich lavas. The related samples have low 206Pb/ 204Pb and 208Pb/ 204Pb but normal 207Pb/ 204Pb, suggesting a recent decrease of U/Pb and Th/Pb, for instance through sequestration of Pb into sulfides. Olivine and sulfides, which are both denser than silicate melts, could be entrained with magma pulses, which give rise to high-flux oceanite eruptions.

Lead and strontium isotopic evidence for crustal interaction and compositional zonation in the source regions of Pleistocene basaltic and rhyolitic magmas of the Coso volcanic field, California

USGS Publications Warehouse

Bacon, C.R.; Kurasawa, H.; Delevaux, M.H.; Kistler, R.W.; Doe, B.R.

1984-01-01

The isotopic compositions of Pb and Sr in Pleistocene basalt, high-silica rhyolite, and andesitic inclusions in rhyolite of the Coso volcanic field indicate that these rocks were derived from different levels of compositionally zoned magmatic systems. The 2 earliest rhyolites probably were tapped from short-lived silicic reservoirs, in contrast to the other 36 rhyolite domes and lava flows which the isotopic data suggest may have been leaked from the top of a single, long-lived magmatic system. Most Coso basalts show isotopic, geochemical, and mineralogic evidence of interaction with crustal rocks, but one analyzed flow has isotopic ratios that may represent mantle values (87Sr/86Sr=0.7036,206Pb/204Pb=19.05,207Pb/204Pb=15.62,208Pb/204Pb= 38.63). The (initial) isotopic composition of typical rhyolite (87Sr/86Sr=0.7053,206Pb/204Pb=19.29,207Pb/204Pb= 15.68,208Pb/204Pb=39.00) is representative of the middle or upper crust. Andesitic inclusions in the rhyolites are evidently samples of hybrid magmas from the silicic/mafic interface in vertically zoned magma reservoirs. Silicic end-member compositions inferred for these mixed magmas, however, are not those of erupted rhyolite but reflect the zonation within the silicic part of the magma reservoir. The compositional contrast at the interface between mafic and silicic parts of these systems apparently was greater for the earlier, smaller reservoirs. ?? 1984 Springer-Verlag.

Neutron density distributions of {sup 204,206,208}Pb deduced via proton elastic scattering at E{sub p}=295 MeV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zenihiro, J.; Sakaguchi, H.; Murakami, T.

Cross sections and analyzing powers for polarized proton elastic scattering from {sup 58}Ni, and {sup 204,206,208}Pb were measured at intermediate energy E{sub p}=295 MeV. An effective relativistic Love-Franey interaction is tuned to reproduce {sup 58}Ni scattering data within the framework of the relativistic impulse approximation. The neutron densities of the lead isotopes are deduced using model-independent sum-of-Gaussians distributions. Their error envelopes are estimated by a new {chi}{sup 2} criterion including uncertainties associated with the reaction model. The systematic behaviors of extracted error envelopes of the neutron density distributions in {sup 204,206,208}Pb are presented. The extracted neutron and proton density distributionmore » of {sup 208}Pb gives a neutron skin thickness of {Delta}r{sub np}=0.211{sub -0.063}{sup +0.054} fm.« less

TRPM3 and miR-204 establish a regulatory circuit that controls oncogenic autophagy in clear cell renal cell carcinoma

PubMed Central

Hall, Daniel P.; Cost, Nicholas G.; Hegde, Shailaja; Kellner, Emily; Mikhaylova, Olga; Stratton, Yiwen; Ehmer, Birgit; Abplanalp, William A.; Pandey, Raghav; Biesiada, Jacek; Harteneck, Christian; Plas, David R.; Meller, Jarek; Czyzyk-Krzeska, Maria F.

2014-01-01

Summary Autophagy promotes tumor growth by generating nutrients from the degradation of intracellular structures. Here we establish, using shRNAs, a dominant negative mutant, and a pharmacologic inhibitor, mefenamic acid (MFA), that the Transient Receptor Potential Melastatin 3 (TRPM3) channel promotes growth of clear cell renal cell carcinoma (ccRCC) and stimulates MAP1LC3A (LC3A) and MAP1LC3B (LC3B) autophagy. Increased expression of TRPM3 in RCC leads to Ca2+ influx, activation of CAMKK2, AMPK, and ULK1, and phagophore formation. In addition, TRPM3 Ca2+ and Zn2+ fluxes inhibit miR-214 which directly targets LC3A and LC3B. The von Hippel-Lindau tumor suppressor (VHL) represses TRPM3 through miR-204 directly and indirectly through another miR-204 target, Caveolin 1 (CAV1). PMID:25517751

24 CFR 92.204 - Applicability of requirements to entities that receive a reallocation of HOME funds, other than...

Code of Federal Regulations, 2012 CFR

2012-04-01

... affirmative marketing requirements, labor requirements, and lead-based paint requirements, applicable to participating jurisdictions. (c) Subpart B (Allocation Formula), subpart C (Consortia; Designation and...

24 CFR 92.204 - Applicability of requirements to entities that receive a reallocation of HOME funds, other than...

Code of Federal Regulations, 2014 CFR

2014-04-01

... affirmative marketing requirements, labor requirements, and lead-based paint requirements, applicable to participating jurisdictions. (c) Subpart B (Allocation Formula), subpart C (Consortia; Designation and...

24 CFR 92.204 - Applicability of requirements to entities that receive a reallocation of HOME funds, other than...

Code of Federal Regulations, 2011 CFR

2011-04-01

... affirmative marketing requirements, labor requirements, and lead-based paint requirements, applicable to participating jurisdictions. (c) Subpart B (Allocation Formula), subpart C (Consortia; Designation and...

24 CFR 92.204 - Applicability of requirements to entities that receive a reallocation of HOME funds, other than...

Code of Federal Regulations, 2010 CFR

2010-04-01

... affirmative marketing requirements, labor requirements, and lead-based paint requirements, applicable to participating jurisdictions. (c) Subpart B (Allocation Formula), subpart C (Consortia; Designation and...

24 CFR 92.204 - Applicability of requirements to entities that receive a reallocation of HOME funds, other than...

Code of Federal Regulations, 2013 CFR

2013-04-01

... affirmative marketing requirements, labor requirements, and lead-based paint requirements, applicable to participating jurisdictions. (c) Subpart B (Allocation Formula), subpart C (Consortia; Designation and...

Geology, S-Pb isotopes, and 40Ar/39Ar geochronology of the Zhaxikang Sb-Pb-Zn-Ag deposit in Southern Tibet: implications for multiple mineralization events at Zhaxikang

NASA Astrophysics Data System (ADS)

Sun, Xiang; Zheng, Youye; Pirajno, Franco; McCuaig, T. Campbell; Yu, Miao; Xia, Shenlan; Song, Qingjie; Chang, Huifang

2018-03-01

Several Au, Sb, Sb-Au, Pb-Zn, and Sb-Pb-Zn-Ag deposits are present throughout the North Himalaya in southern Tibet, China. The largest Sb-Pb-Zn-Ag deposit is Zhaxikang (18 Mt at 0.6 wt% Sb, 2.0 wt% Pb, 3.5 wt% Zn, and 78 g/t Ag). Zhaxikang veins are hosted within N-S trending faults, which crosscut the Early-Middle Jurassic Ridang Formation consisting of shale interbedded with sandstone and limestone deposited on a passive continental margin. Ore paragenesis indicates that Zhaxikang mineralization occurred in two main phases composed of six total stages. The initial phase was characterized by assemblages of fine-grained Mn-Fe carbonate + arsenopyrite + pyrite + sphalerite (stage 1), followed by relatively coarse-grained Mn-Fe carbonate + Fe-rich sphalerite + galena + pyrite (stage 2). The second phase was marked by assemblages of quartz + pyrite + Fe-poor sphalerite and Ag-rich galena + tetrahedrite + sericite (stage 3), quartz + Sb-Pb sulfosalt minerals mainly composed of boulangerite and jamesonite (stage 4), quartz + stibnite ± cinnabar (stage 5), and quartz ± calcite (stage 6). Sulfides of stage 2 have δ34SV-CDT of 8.4-12.0‰, 206Pb/204Pb ratios of 19.648 to 19.659, 207Pb/204Pb ratios of 15.788 to 15.812, and 208Pb/204Pb ratios of 40.035 to 40.153. Sulfides of stage 3 have similar δ34SV-CDT of 6.1-11.2‰ and relatively more radiogenic lead isotopes (206Pb/204Pb = 19.683-19.792). Stage 4 Sb-Pb sulfosalt minerals have δ34SV-CDT of 5.0-7.2‰ and even more radiogenic lead (206Pb/204Pb = 19.811-19.981). By contrast, stibnite of stage 5 has δ34SV-CDT of 4.5-7.8‰ and less radiogenic lead (206Pb/204Pb = 18.880-18.974). Taken together with the geological observations that the Pb-Zn-bearing Mn-Fe carbonate veins were crosscut by various types of quartz veins, sphalerite and galena of stage 2 underwent dissolution and remobilization, and that Sb-Pb(-Fe) sulfosalts formed at the expense of Pb from stage 2 galena and of Fe from stage 2 sphalerite, we argue that the early Pb-Zn veins were overprinted by later Sb-rich fluids. Stage 2 fluids were likely acidic and oxidized and leached lead from high-grade metamorphic rocks of the Greater Himalayan crystalline complex (GHC) and sulfur from reduced rocks, such as slate of the Ridang Formation, along N-S trending faults, leading to precipitation of Pb-Zn sulfides and Mn-Fe carbonate and formation of solution collapse breccias. Later Sb-rich fluids leached Pb from the GHC and the pre-existing sulfides and deposited Fe-poor sphalerite, Ag-rich galena, tetrahedrite, Sb-Pb sulfosalts, and stibnite in quartz veins that cut pre-existing Pb-Zn-bearing Mn-Fe carbonate veins. The Sb-rich fluids also likely leached Pb from Early Cretaceous gabbro and formed stibnite at shallow levels where early Pb-Zn-bearing Mn-Fe carbonate veins are absent. A sericite 40Ar-39Ar plateau age of 17.9 ± 0.5 Ma from stage 3 veins represents the timing of the onset of stage 3 mineralization.

The Earth's missing lead may not be in the core.

PubMed

Lagos, M; Ballhaus, C; Münker, C; Wohlgemuth-Ueberwasser, C; Berndt, J; Kuzmin, Dmitry V

2008-11-06

Relative to the CI chondrite class of meteorites (widely thought to be the 'building blocks' of the terrestrial planets), the Earth is depleted in volatile elements. For most elements this depletion is thought to be a solar nebular signature, as chondrites show depletions qualitatively similar to that of the Earth. On the other hand, as lead is a volatile element, some Pb may also have been lost after accretion. The unique (206)Pb/(204)Pb and (207)Pb/(204)Pb ratios of the Earth's mantle suggest that some lead was lost about 50 to 130 Myr after Solar System formation. This has commonly been explained by lead lost via the segregation of a sulphide melt to the Earth's core, which assumes that lead has an affinity towards sulphide. Some models, however, have reconciled the Earth's lead deficit with volatilization. Whichever model is preferred, the broad coincidence of U-Pb model ages with the age of the Moon suggests that lead loss may be related to the Moon-forming impact. Here we report partitioning experiments in metal-sulphide-silicate systems. We show that lead is neither siderophile nor chalcophile enough to explain the high U/Pb ratio of the Earth's mantle as being a result of lead pumping to the core. The Earth may have accreted from initially volatile-depleted material, some lead may have been lost to degassing following the Moon-forming giant impact, or a hidden reservoir exists in the deep mantle with lead isotope compositions complementary to upper-mantle values; it is unlikely though that the missing lead resides in the core.

Lead Isotope Geochemistry of Mississippi Valley-Type Pb-Zn Deposits of the Ozark Region, U.S. Midcontinent: Constraints on the Origin of Ore Metals

NASA Astrophysics Data System (ADS)

Potra, A.

2015-12-01

The Ozark region of the U.S. midcontinent is one of the world's most important provinces of MVT mineralization, hosting world-class ore deposits. The ores in the Tri-State (TS) and Northern Arkansas (NA) districts, dominated by sphalerite, are mainly hosted by platform carbonate rocks and vary in age from Ordovician and Mississippian for NA and Mississippian for TS. The deposits are considered to have formed from a regional hydrothermal flow system consisting of sedimentary brines discharged from the Arkoma basin and adjacent platform during the Late Pennsylvanian to Early Permian Ouachita orogeny. New MC-ICP-MS Pb isotope analyses of sphalerites are presented in order to compare and contrast the isotopic signature of ores from the NA and TS districts with those from other MVT districts from central and eastern US and trace metal sources. The Pb isotope ratios of ores from the TS District (208Pb/204Pb between 40.7443 and 41.2626; 207Pb/204Pb between 15.8633 and 15.9571; 206Pb/204Pb between 21.8373 and 22.1956) plot in an area that is superimposed on the Pb isotope field defined by samples from the Central Missouri District, suggesting similar metal sources. The sphalerites are less radiogenic than samples from the Upper Mississippi Valley District, but more radiogenic than samples from any other MVT district. Sphalerites from the NA District have lower Pb isotope values (208Pb/204Pb between 39.4633 and 40.8863; 207Pb/204Pb between 15.8216 and 15.9176; 206Pb/204Pb between 20.2396 and 21.6438) than the TS District ores; they plot below the field defined by samples from the Illinois-Kentucky district and overlap the field defined by ores from the Southeast Missouri (Viburnum and Old Lead Belt) district, implying similar metal sources. Current data suggest that basement of Grenvillian age (1 - 1.2 by), thought to be present in Arkansas, to the south of the Viburnum Trend, may be a likely source of the radiogenic Pb component. Pb data from ores in the NA and the Southeast Missouri districts are collinear with data from the TS and Central Missouri districts.

Proline Can Have Opposite Effects on Fast and Slow Protein Folding Phases

PubMed Central

Osváth, Szabolcs; Gruebele, Martin

2003-01-01

Proline isomerization is well known to cause additional slow phases during protein refolding. We address a new question: does the presence of prolines significantly affect the very fast kinetics that lead to the formation of folding intermediates? We examined both the very slow (10–100 min) and very fast (4 μs–2.5 ms) folding kinetics of the two-domain enzyme yeast phosphoglycerate kinase by temperature-jump relaxation. Phosphoglycerate kinase contains a conserved cis-proline in position 204, in addition to several trans-prolines. Native cis-prolines have the largest effect on folding kinetics because the unfolded state favors trans isomerization, so we compared the kinetics of a P204H mutant with the wild-type as a proof of principle. The presence of Pro-204 causes an additional slow phase upon refolding from the cold denatured state, as reported in the literature. Contrary to this, the fast folding events are sped up in the presence of the cis-proline, probably by restriction of the conformational space accessible to the molecule. The wild-type and Pro204His mutant would be excellent models for off-lattice simulations probing the effects of conformational restriction on short timescales. PMID:12885665

Unradiogenic Pb Anomalies in Historical Lavas of Piton de la Fournaise (Reunion Island)

NASA Astrophysics Data System (ADS)

Vlastelic, I.

2008-12-01

A detailed investigation (218 samples) of Pb isotope variations in the most recent (1975-2007), well- documented and densely sampled eruptions of Piton de la Fournaise has been undertaken (Vlastelic et al, in press). Lead isotopes exhibit smooth temporal fluctuations (18.87<206Pb/204Pb<18.94) on which superimpose rare (5), but pronounced unradiogenic spikes (206Pb/204Pb down to 17.63). In 208Pb/204Pb vs. 206Pb/204Pb space, normal and anomalous samples plot along a single linear array. In 207Pb/204Pb vs. 206Pb/204Pb space, normal samples define an array whose slope (0.16) is commonly observed in ocean island basalts, whereas anomalous samples define less steep arrays (slopes down to 0.04). It follows that some of the anomalous samples have unusually high 207Pb/204Pb for their 206Pb/204Pb. These latter are enriched in Pb by a factor three. The lack of reproducibility of isotopic analyses suggests that samples are heterogeneous at a sub-millimeter scale. The origin of the unradiogenic anomalies is enigmatic. Leaching experiments rule out anthropogenic contamination. Interaction of plume melts with a contaminant genetically unrelated to the Reunion plume is possible although not supported by trace-element and Sr-Nd isotope signatures indistinguishable from normal lavas. On the other hand, interaction with or entrainment of Pb-rich, most likely unradiogenic sulfides could affect specifically Pb isotope compositions. Inspection of the well-know eruptions history reveals that the isotopic anomalies coincide with transitions from basalts to oceanites (lavas rich in cumulative olivine). Olivine and sulfides, which are both denser than silicate melts, could be entrained with magma pulses, which give rise to high-flux oceanite eruptions. Some sulfides may originate from the oceanic crust. Others may originate from sulfide solidus depth (c.a. 160 km) where sulfides melts are expected to pond (Hart and Gaetani, 2006). These deep sulfides melts could be remnants of past melting events of the Reunion plume. References Hart, S.R., Gaetani, G.A., 2006. Contrib. Mineral. Petrol. 152, 295-308. Vlastelic, I., et al., 2008. J. Volcanol. Geotherm. Res., in press.

The identification of lead ammunition as a source of lead exposure in First Nations: the use of lead isotope ratios.

PubMed

Tsuji, Leonard J S; Wainman, Bruce C; Martin, Ian D; Sutherland, Celine; Weber, Jean-Philippe; Dumas, Pierre; Nieboer, Evert

2008-04-15

The use of lead shotshell to hunt water birds has been associated with lead-contamination in game meat. However, evidence illustrating that lead shotshell is a source of lead exposure in subsistence hunting groups cannot be deemed definitive. This study seeks to determine whether lead shotshell constitutes a source of lead exposure using lead isotope ratios. We examined stable lead isotope ratios for lichens, lead shotshell and bullets, and blood from residents of Fort Albany and Kashechewan First Nations, and the City of Hamilton, Ontario, Canada. Data were analyzed using ANOVA and regression analyses. ANOVA of isotope ratios for blood revealed significant differences with respect to location, but not sex. Hamilton differed from both Kashechewan and Fort Albany; however, the First Nations did not differ from each other. ANOVA of the isotope ratios for lead ammunition and lichens revealed no significant differences between lichen groups (north and south) and for the lead ammunition sources (pellets and bullets). A plot of (206)Pb/(204)Pb and (206)Pb/(207)Pb values illustrated that lichens and lead ammunition were distinct groupings and only the 95% confidence ellipse of the First Nations group overlapped that of lead ammunition. In addition, partial correlations between blood-lead levels (adjusted for age) and isotope ratios revealed significant (p<0.05) positive correlations for (206)Pb/(204)Pb and (206)Pb/(207)Pb, and a significant negative correlation for (208)Pb/(206)Pb, as predicted if leaded ammunition were the source of lead exposure. In conclusion, lead ammunition was identified as a source of lead exposure for First Nations people; however, the isotope ratios for lead shotshell pellets and bullets were indistinguishable. Thus, lead-contaminated meat from game harvested with lead bullets may also be contributing to the lead body burden.

Dietary lead: effects on hepatic fatty acid composition in chicks.

PubMed

Donaldson, W E; Leeming, T K

1984-03-30

Arbor Acre broiler chicks were fed diets containing 0, 500, 750, 1000, 2000, or 4000 ppm lead (as Pb acetate X 3 H2O) from day-old through 21 days of age. There were 8 groups of 10 male chicks per lead level. Eight chicks from each dietary lead level were killed at 21 days, and hepatic fatty acid composition was determined for each chick by gas-liquid chromatography. Increasing dietary lead levels decreased the concentrations of 16:1 and 18:1 fatty acids (first No. = No. carbons; second No. = No. double bonds) and increased the concentrations of 18:0 and 20:4. The concentration of 18:2 fatty acids did not differ significantly from control values for any level of lead. However, the ratio 18:2/20:4 declined from a control value of 3.3 to approximately 2 for all lead treatments. The ratio of saturated/monoenoic fatty acids increased with dietary lead levels above 1000 ppm. In a second experiment 10 male broiler chicks per treatment were fed either a control diet or the control diet plus 2000 ppm lead, 60 ppm cadmium, 500 ppm mercury, or 10 ppm selenium (as Pb acetate X 3 H2O, CdSO4, HgCl2, or Na2SeO3, respectively) for 21 days. Six chicks from each group were killed at 21 days, and hepatic fatty acid composition was determined for each chick. In comparison to control, the ratio 18:2/20:4 was lowered by lead but unaffected by cadmium, mercury, and selenium. The data suggest that lead may increase tissue peroxidation (as noted by other workers) via a relative increase of 20:4 fatty acid and that a decrease of hepatic ratio 18:2/20:4 may be a specific sign of lead toxicity.

miR-204 reverses temozolomide resistance and inhibits cancer initiating cells phenotypes by degrading FAP-α in glioblastoma.

PubMed

Yang, Yun-Na; Zhang, Xiang-Hua; Wang, Yan-Ming; Zhang, Xi; Gu, Zheng

2018-05-01

Malignant gliomas are treated with temozolomide (TMZ) at present, but often exhibit resistance to this agent. Cancer-initiating cells (CICs) have been suggested to lead to TMZ resistance. The mechanisms underlying CICs-based TMZ resistance are not fully understood. MicroRNAs (miRNAs) have been demonstrated to serve important roles in tumorigenesis and TMZ resistance. In the present study, a sphere forming assay and western blot analysis were performed to detect the formation of CICs and fibroblast activation protein α (FAP-α) protein expression. It was revealed that TMZ resistance promoted the formation of CICs and upregulated FAP-α expression in glioblastoma cells. Over-expressing FAP-α was also demonstrated to promote TMZ resistance and induce the formation of CICs in U251MG cells. In addition, using a reverse transcription-quantitative polymerase chain reaction, it was observed that miR-204 was downregulated in U251MG-resistant (-R) cells. miR-204 expression negatively correlated with the FAP-α levels in human glioblastoma tissues, and it may inhibit the formation of CICs and reverse TMZ resistance in U251MG-R cells. Therefore, it was concluded that miR-204 reversed temozolomide resistance and inhibited CICs phenotypes by degrading FAP-α in glioblastoma.

miR-204 reverses temozolomide resistance and inhibits cancer initiating cells phenotypes by degrading FAP-α in glioblastoma

PubMed Central

Yang, Yun-Na; Zhang, Xiang-Hua; Wang, Yan-Ming; Zhang, Xi; Gu, Zheng

2018-01-01

Malignant gliomas are treated with temozolomide (TMZ) at present, but often exhibit resistance to this agent. Cancer-initiating cells (CICs) have been suggested to lead to TMZ resistance. The mechanisms underlying CICs-based TMZ resistance are not fully understood. MicroRNAs (miRNAs) have been demonstrated to serve important roles in tumorigenesis and TMZ resistance. In the present study, a sphere forming assay and western blot analysis were performed to detect the formation of CICs and fibroblast activation protein α (FAP-α) protein expression. It was revealed that TMZ resistance promoted the formation of CICs and upregulated FAP-α expression in glioblastoma cells. Over-expressing FAP-α was also demonstrated to promote TMZ resistance and induce the formation of CICs in U251MG cells. In addition, using a reverse transcription-quantitative polymerase chain reaction, it was observed that miR-204 was downregulated in U251MG-resistant (-R) cells. miR-204 expression negatively correlated with the FAP-α levels in human glioblastoma tissues, and it may inhibit the formation of CICs and reverse TMZ resistance in U251MG-R cells. Therefore, it was concluded that miR-204 reversed temozolomide resistance and inhibited CICs phenotypes by degrading FAP-α in glioblastoma. PMID:29725461

Lead in the Getchell-Turquoise ridge Carlin-type gold deposits from the perspective of potential igneous and sedimentary rock sources in Northern Nevada: Implications for fluid and metal sources

USGS Publications Warehouse

Tosdal, R.M.; Cline, J.S.; Fanning, C.M.; Wooden, J.L.

2003-01-01

Lead isotope compositions of bulk mineral samples (fluorite, orpiment, and realgar) determined using conventional techniques and of ore-stage arsenian pyrite using the Sensitive High Resolution Ion-Microprobe (SHRIMP) in the Getchell and Turquoise Ridge Carlin-type gold deposits (Osgood Mountains) require contribution from two different Pb sources. One Pb source dominates the ore stage. It has a limited Pb isotope range characterized by 208Pb/206Pb values of 2.000 to 2.005 and 207Pb/206Pb values of 0.8031 to 0.8075, as recorded by 10-??m-diameter spot SHRIMP analyses of ore-stage arsenian pyrite. These values approximately correspond to 206Pb/204Pb of 19.3 to 19.6, 207Pb/204Pb of 15.65 to 15.75, and 208Pb/204Pb of 39.2 to 39.5. This Pb source is isotopically similar to that in average Neoproterozoic and Cambrian elastic rocks but not to any potential magmatic sources. Whether those clastic rocks provided Pb to the ore fluid cannot be unequivocally proven because their Pb isotope compositions over the same range as in ore-stage arsenian pyrite are similar to those of Ordovician to Devonian siliciclastic and calcareous rocks. The Pb source in the calcareous rocks most likely is largely detrital minerals, since that detritus was derived from the same sources as the detritus in the Neoproterozoic and Cambrian clastic rocks. The second Pb source is characterized by a large range of 206Pb/204Pb values (18-34) with a limited range of 208Pb/204Pb values (38.1-39.5), indicating low but variable Th/U and high and variable U/Pb values. The second Pb source dominates late and postore-stage minerals but is also found in preore sulfide minerals. These Pb isotope characteristics typify Ordovician to Devonian siliciclastic and calcareous rocks around the Carlin trend in northeast Nevada. Petrologically similar rocks host the Getchell and Turquoise Ridge deposits. Lead from the second source was either contributed from the host sedimentary rock sequences or brought into the hydrothermal system by oxidized ground water as the system collapsed. Late ore- and postore-stage sulfide minerals (pyrite, orpiment, and stibnite) from the Betze-Post and Meikle deposits in the Carlin trend and from the Jerritt Canyon mining district have Pb isotope characteristics similar to those determined in Getchell and Turquoise Ridge. This observation suggests that the Pb isotope compositions of their ore fluids may be similar to those at Getchell and Turquoise Ridge. Two models can explain the Pb isotope compositions of the ore-stage arsenian pyrite versus the late ore or postore sulfide minerals. In either model, Pb from the Ordovician to Devonian siliciclastic and calcareous rock source enters the hydrothermal system late in the ore stage but not to any extent during the main stage of ore deposition. In one model, ore-stage Pb was derived from a source with Pb isotope compositions similar to those of the Neoproterozoic and Cambrian clastic sequence, transported as part of the ore fluid and then deposited in the ore-stage arsenian pyrite and fluorite. The second model is based on the observation that the Pb isotope characteristics of the ore-stage minerals also are found in some Ordovician to Devonian calcareous and siliciclastic rocks. Hence, ore-stage Pb could have been derived locally and simply concentrated during the ore stage. Critical to the second model is the removal of all high 206Pb/204Pb (>20) material during alteration. It Also requires the retention of only the low 206Pb/204Pb component of the Ordovician to Devonian sedimentary rocks. This critical step is possible only if the high 206Pb/204Pb values are contained in readily dissolvable mineral phases, whereas the low 206Pb/204Pb values are found only in refractory minerals that released Pb during a final alteration stage just prior deposition of auriferous arsenian pyrite. Distinguishing between Pb transported with the ore fluid or inherited from the site of mineral deposition is not straightforward

Ore genesis of the Wusihe carbonate-hosted Zn-Pb deposit in the Dadu River Valley district, Yangtze Block, SW China: evidence from ore geology, S-Pb isotopes, and sphalerite Rb-Sr dating

NASA Astrophysics Data System (ADS)

Xiong, Suo-Fei; Gong, Yong-Jun; Jiang, Shao-Yong; Zhang, Xiao-Jing; Li, Qian; Zeng, Guo-Ping

2018-01-01

The Wusihe carbonate-hosted Zn-Pb deposit (3.7 Mt. Zn + Pb at a grade of 8.6% Zn and 2.0% Pb) is the largest deposit in the Dadu River Valley district of the Sichuan-Yunnan-Guizhou metallogenic province of southwest China. Three types of orebodies occur: (1) stratiform, banded and lamellar, within dolomite of the Neoproterozoic Dengying Formation; (2) vein type; and (3) breccia type. Four stages of mineralization are distinguished: (i) pyrite stage, (ii) pyrite-pyrrhotite-galena-sphalerite-bitumen stage, (iii) sphalerite-galena stage, and (iv) bitumen-calcite stage. Sphalerite and galena from stages II and III show δ34S ranges from +7.1 to +9.7‰ and +9.1 to +13.1‰, respectively. High-precision in situ lead isotope analyses of sulfides show 208Pb/204Pb, 207Pb/204Pb, and 206Pb/204Pb ratios of 37.938 to 38.336, 15.579 to 15.682, and 17.951 to 18.195, respectively, which suggest a mixing of lead from the basement and the host rocks. Rb-Sr isotope analyses for six sphalerite samples of stage II yielded an isochron age of 411 ± 10 Ma (MSWD = 1.4). Combining all available ore geology and geochemical data, together with fluid inclusion data reported previously, we suggest that the Wusihe deposit is a Mississippi Valley-type (MVT) deposit.

Lead isotopes in lichen transplants around a Cu smelter in Russia determined by MC-ICP-MS reveal transient records of multiple sources.

PubMed

Spiro, B; Weiss, D J; Purvis, O W; Mikhailova, I; Williamson, B J; Coles, B J; Udachin, V

2004-12-15

Transplants of the lichen Hypogymnia physodes, which is relatively tolerant to SO2 and heavy metals, were deployed for 3 months over a 60 km long SW-NE transect centered on a highly polluting Cu smelter and its adjoining town of Karabash, southern Urals, Russia. The abundance of 206Pb, 207Pb, 208Pb, and 204Pb were determined by MC-ICP-MS. The measurement of 204Pb revealed critical features, which would otherwise remain concealed: (i) The precise isotope ratios referenced to 204Pb allowed several different sources to be resolved even within the small area covered: (a) the obvious pollutant source of the Karabash Cu smelter; (b) two dispersed sources, likely to include soil with lower and different contributions of thorogenic and uranogenic lead; and (c) one anthropogenic source with higher contribution of 235U derived Pb. (ii) In part of the transect, the Pb isotope composition changed while the Pb concentrations remained the same. This indicates that the Pb content of the transplantation material from the background site was largely replaced and that the transplants provide a transient record reflecting a continuous accumulation and loss of environmental Pb, probably mainly in the form of extracellular particles. Overall, the method of lichen transplantation coupled with Pb isotope ratio determinations proved effective in assessing the usefulness of lichens in biomonitoring and in resolving different sources of atmospheric deposition.

Spectroscopic Measurement of LEAD-204 Isotope Shift and LEAD-205 Nuclear Spin.

NASA Astrophysics Data System (ADS)

Schonberger, Peter

The isotope shift of ('204)Pb and the nuclear spin of 1.4 x 10('7)-y ('205)Pb was determined from a high -resolution optical measurement of the 6p('2) ('3)P(,o) -6p7s('3)P(,1)('o) 283.3-nm resonance line. The value of the shift, relative to ('208)Pb is -140.2(8) x 10('-3)cm(' -1), the negative sign indicating a shift to lower wave numbers. The precision is 3-4 times greater than that of previous measurements. The spin of ('205)Pb l = 5/2 was obtained from the measurement of the relative intensities of its three hyperfine components. This method of absorption spectroscopy determination of ground state nuclear spin is applicable to any stable or longlived isotope. High resolution optical absorption spectra were obtained with a 25.4cm diffraction grating in a 9.1m focal length Czerny-Turner spectrometer. A signal-averaging scanning technique was used to record the spectra. Increased precision in the isotope shift measurement was attained by using separated isotope samples of ('204)Pb and ('207)Pb. A controlled amount of the later was incorporated in the absorption cell to provide internal calibration by its 6p7s ('3)P(,1)('o) hfs separation. Absorption spectra were recorded for several optical thicknesses of the absorber. A single spin value of increased precision was derived from the entire set of combined data.

Stable lead isotopes reveal a natural source of high lead concentrations to gasoline-contaminated groundwater

USGS Publications Warehouse

Landmeyer, J.E.; Bradley, P.M.; Bullen, T.D.

2003-01-01

Concentrations of total lead as high as 1,600 ??g/L were detected in gasoline-contaminated and uncontaminated groundwater at three gasoline-release sites in South Carolina. Total lead concentrations were highest in turbid groundwater samples from gasoline-contaminated and uncontaminated wells, whereas lower turbidity groundwater samples (collected using low-flow methods) had lower total lead concentrations. Dissolved lead concentrations in all wells sampled, however, were less than 15 ??g total lead/L, the current United States Environmental Protection Agency (US EPA) maximum contaminant level (MCL). Because many total lead concentrations exceeded the MCL, the source of lead to the groundwater system at two of the three sites was investigated using a stable lead isotope ratio approach. Plots of the stable isotope ratios of lead (Pb) in groundwater as 207Pb/206Pb versus 208Pb/206Pb, and 208Pb/204Pb versus 206Pb/204Pb were similar to ratios characteristic of lead-based minerals in local rocks of the southeastern US, and were not similar to the stable lead isotopes ratios characteristic of distant lead ore deposits such as Broken Hill, Australia, used to produce tetraethyl lead in gasoline products prior to its phase-out and ban in the United States. Moreover, the isotopic composition of dissolved lead was equivalent to the isotopic composition of total lead in turbid samples collected from the same well, suggesting that the majority of the lead detected in the groundwater samples was associated with sediment particulates of indigenous aquifer material, rather than lead associated with spilled leaded gasoline. The results of this investigation indicate that (1) lead detected at some gasoline-release sites may be derived from the local aquifer material, rather than the gasoline release, and consequently may affect site-specific remediation goals; (2) non-low flow groundwater sampling methods, such as a disposable bailer, may result in turbid groundwater samples and high total lead concentrations, and; (3) stable lead isotopes can be used to clarify the source of lead detected above permissible levels in gasoline-contaminated groundwater systems.

Lead mobilization during tectonic reactivation of the western Baltic Shield

DOE Office of Scientific and Technical Information (OSTI.GOV)

Romer, R.L.; Wright, J.E.

Lead isotope data from sulfide deposits of the western part of the Baltic Shield define mixing lines in the [sup 206]Pb/[sup 204]Pb-[sup 207]Pb/[sup 204]Pb diagram. Lead from two types of sulfide deposits have been investigated: (1) Exhalative and volcanogenic deposits that are syngenetic with their host rocks; and (2) vein deposits. The syngenetic deposits locally show a very wide range of lead isotopic compositions that reflect a variable addition of highly radiogenic lead, while the vein deposits, although they have radiogenic lead isotopic compositions, exhibit only limited isotopic variations. In different provinces of the shield, both types of deposits fallmore » on the same lead mixing array. The slope of the lead mixing lines varies as a function of the age of basement rocks and the age of the tectonic event which produced the lead mobilization and therefore relates the source rock age with the age of lead mobilization. Calculated mixing ages fall into several short time periods that correspond either to orogenic events or to major phases of continental rifting. The orogenic events are the ca 360--430 Ma Caledonian, ca 900--1100 Ma Sveconorwegian, and the ca 1800--1900 Ma Svecofennian orogenic cycles. The rifting events correspond to the formation of the ca 280 Ma Oslo rift and the Ordovician (ca 450 Ma) graben system in the area of the present Gulf of Bothnia. Each mixing age indicates that lead was mobilized, probably as a consequence of mild thermal disturbances, and that the crust was permeable to lead migration. The data show that the geographic distribution of sulfide deposits with highly radiogenic lead isotopic compositions coincides with old graben systems, orogenic belts, and orogenic forelands on the Baltic Shield. The ages of vein deposits and their geographic distribution demonstrate multiple tectonic reactivation of the interior of the Baltic Shield in response to orogenic events at its margin. 68 refs., 6 refs., 4 tabs.« less

78 FR 80379 - Federal Acquisition Regulation; Trade Agreements Thresholds

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-31

... 79,507 79,507 10,335,931 Oman FTA 204,000 204,000 10,335,931 Panama FTA 204,000 204,000 7,864,000...,335,931 --Mexico 79,507 79,507 10,335,931 Oman FTA 204,000 204,000 10,335,931 Panama FTA 204,000 204...

Successful treatment of extreme acute lead intoxication.

PubMed

Mikler, J; Banovcin, P; Jesenak, M; Hamzikova, J; Statelova, D

2009-03-01

Severe acute lead intoxications are rare and are associated with accidental or purposeful ingestion. There were only few cases of severe to fatal poisonings reported in literature in children. We report a case of acute lead intoxication in a child with extremely high lead blood level of 20.4 micromol/L (422.7 microg/dL), who was treated with chelation and in whom significant organ dysfunction did not develop. Documented significant high level above 3.37 micromol/L (corresponding to 70 microg/dL) in this patient persisted for approximately 24 h. Adequate, single or combined chelatation therapy in early phase of acute lead poisoning is essential for the further patient's outcome.

Variable sources for Cretaceous to recent HIMU and HIMU-like intraplate magmatism in New Zealand

NASA Astrophysics Data System (ADS)

van der Meer, Q. H. A.; Waight, T. E.; Scott, J. M.; Münker, C.

2017-07-01

Continental intraplate magmas with isotopic affinities similar to HIMU are identified worldwide. Involvement of an asthenospheric HIMU or HIMU-like source is contested because the characteristic radiogenic Pb compositions coupled with unradiogenic Sr and intermediate Nd and Hf compositions can also result from in-situ ingrowth in metasomatised lithospheric mantle. Sr-Nd-Pb-Hf isotopic compositions of late Cretaceous lamprophyre dikes from Westland, New Zealand, provide new insights into the formation of a HIMU-like alkaline intraplate magmatic province under the Zealandia continent. The oldest (102-100 Ma) calc-alkaline lamprophyres are compositionally similar to the preceding arc-magmatism (206Pb/204Pb(i) = 18.6, 207Pb/204Pb(i) = 15.62, 208Pb/204Pb(i) = 38.6, 87Sr/86Sr(i) = 0.7063-0.7074, εNd(i) = -2.1 - +0.1 and εHf(i) = -0.2 - +2.3) and are interpreted as melts originating from subduction-modified lithosphere. Alkaline dikes erupted on the inboard Gondwana margin shortly after cessation of subduction (92-84 Ma) have heterogeneous isotopic properties: 206Pb/204Pb(i) = 18.7 to 19.4, 207Pb/204Pb(i) = 15.60 to 15.65, 208Pb/204Pb(i) = 38.6 to 39.4, 87Sr/86Sr(i) = 0.7031 to 0.7068, εNd(i) = +4.5 to +8.0 and εHf(i) = +5.1 to +8.0. Melt compositions point to an amphibole-bearing spinel facies lithospheric mantle source enriched by metasomatism that introduced, amongst many elements, U + Th which lead to rapid ingrowth to HIMU-like compositions. Importantly, this HIMU-like source enrichment appears to have completely originated from the complex local subduction history. A coeval episode of alkaline magmatism (mainly 98-82 Ma) occurred outboard of Gondwana's former active margin and on the Hikurangi oceanic plateau (accreted to Zealandia in the Early Cretaceous) with compositions closer to true HIMU (206Pb/204Pb(i) ≈ 20.5, 207Pb/204Pb(i) ≈ 15.7, 208Pb/204Pb(i) ≈ 40.0, εNd(i) ≈ 4.5 and εHf(i) ≈ 4.0). In contrast to the inboard HIMU-like magmas, the radiogenic 207Pb/204Pb and relatively unradiogenic Nd and Hf require an ancient enriched source component. This magmatism is interpreted to represent melting of a fossilised HIMU source that resided under the Hikurangi Plateau. These genetically distinct but isotopically similar intraplate reservoirs were separated by the down-going slab under Gondwana's former active margin. Ancient HIMU magmatism was locally replaced by the young HIMU-like type which became dominant across Zealandia during the Late Cretaceous. Our research suggests that the sources for alkaline intraplate magmas with compositions similar to ocean island basalts can be formed either with or without the involvement of a plume-derived component.

Outbreak of fatal childhood lead poisoning related to artisanal gold mining in northwestern Nigeria, 2010.

PubMed

Dooyema, Carrie A; Neri, Antonio; Lo, Yi-Chun; Durant, James; Dargan, Paul I; Swarthout, Todd; Biya, Oladayo; Gidado, Saheed O; Haladu, Suleiman; Sani-Gwarzo, Nasir; Nguku, Patrick M; Akpan, Henry; Idris, Sa'ad; Bashir, Abdullahi M; Brown, Mary Jean

2012-04-01

In May 2010, a team of national and international organizations was assembled to investigate children's deaths due to lead poisoning in villages in northwestern Nigeria. Our goal was to determine the cause of the childhood lead poisoning outbreak, investigate risk factors for child mortality, and identify children < 5 years of age in need of emergency chelation therapy for lead poisoning. We administered a cross-sectional, door-to-door questionnaire in two affected villages, collected blood from children 2-59 months of age, and obtained soil samples from family compounds. Descriptive and bivariate analyses were performed with survey, blood lead, and environmental data. Multivariate logistic regression techniques were used to determine risk factors for childhood mortality. We surveyed 119 family compounds. Of 463 children < 5 years of age, 118 (25%) had died in the previous year. We tested 59% (204/345) of children < 5 years of age, and all were lead poisoned (≥ 10 µg/dL); 97% (198/204) of children had blood lead levels (BLLs) ≥ 45 µg/dL, the threshold for initiating chelation therapy. Gold ore was processed inside two-thirds of the family compounds surveyed. In multivariate modeling, significant risk factors for death in the previous year from suspected lead poisoning included the age of the child, the mother's work at ore-processing activities, community well as primary water source, and the soil lead concentration in the compound. The high levels of environmental contamination, percentage of children < 5 years of age with elevated BLLs (97%, > 45 µg/dL), and incidence of convulsions among children before death (82%) suggest that most of the recent childhood deaths in the two surveyed villages were caused by acute lead poisoning from gold ore-processing activities. Control measures included environmental remediation, chelation therapy, public health education, and control of mining activities.

Outbreak of Fatal Childhood Lead Poisoning Related to Artisanal Gold Mining in Northwestern Nigeria, 2010

PubMed Central

Neri, Antonio; Lo, Yi-Chun; Durant, James; Dargan, Paul I.; Swarthout, Todd; Biya, Oladayo; Gidado, Saheed O.; Haladu, Suleiman; Sani-Gwarzo, Nasir; Nguku, Patrick M.; Akpan, Henry; Idris, Sa’ad; Bashir, Abdullahi M.; Brown, Mary Jean

2011-01-01

Background: In May 2010, a team of national and international organizations was assembled to investigate children’s deaths due to lead poisoning in villages in northwestern Nigeria. Objectives: Our goal was to determine the cause of the childhood lead poisoning outbreak, investigate risk factors for child mortality, and identify children < 5 years of age in need of emergency chelation therapy for lead poisoning. Methods: We administered a cross-sectional, door-to-door questionnaire in two affected villages, collected blood from children 2–59 months of age, and obtained soil samples from family compounds. Descriptive and bivariate analyses were performed with survey, blood lead, and environmental data. Multivariate logistic regression techniques were used to determine risk factors for childhood mortality. Results: We surveyed 119 family compounds. Of 463 children < 5 years of age, 118 (25%) had died in the previous year. We tested 59% (204/345) of children < 5 years of age, and all were lead poisoned (≥ 10 µg/dL); 97% (198/204) of children had blood lead levels (BLLs) ≥ 45 µg/dL, the threshold for initiating chelation therapy. Gold ore was processed inside two-thirds of the family compounds surveyed. In multivariate modeling, significant risk factors for death in the previous year from suspected lead poisoning included the age of the child, the mother’s work at ore-processing activities, community well as primary water source, and the soil lead concentration in the compound. Conclusion: The high levels of environmental contamination, percentage of children < 5 years of age with elevated BLLs (97%, > 45 µg/dL), and incidence of convulsions among children before death (82%) suggest that most of the recent childhood deaths in the two surveyed villages were caused by acute lead poisoning from gold ore–processing activities. Control measures included environmental remediation, chelation therapy, public health education, and control of mining activities. PMID:22186192

44 CFR 204.27-204.40 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-10-01

... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false [Reserved] 204.27-204.40 Section 204.27-204.40 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FIRE MANAGEMENT ASSISTANCE GRANT PROGRAM Declaration Process...

44 CFR 204.27-204.40 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-10-01

... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true [Reserved] 204.27-204.40 Section 204.27-204.40 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FIRE MANAGEMENT ASSISTANCE GRANT PROGRAM Declaration Process...

44 CFR 204.27-204.40 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-10-01

... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false [Reserved] 204.27-204.40 Section 204.27-204.40 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FIRE MANAGEMENT ASSISTANCE GRANT PROGRAM Declaration Process...

44 CFR 204.27-204.40 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false [Reserved] 204.27-204.40 Section 204.27-204.40 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FIRE MANAGEMENT ASSISTANCE GRANT PROGRAM Declaration Process...

44 CFR 204.27-204.40 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false [Reserved] 204.27-204.40 Section 204.27-204.40 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FIRE MANAGEMENT ASSISTANCE GRANT PROGRAM Declaration Process...

The Pb Isotope Pedigree of Western Samoan Volcanics: New Insights From High-Precision Analysis by NEPTUNE ICP/MS

NASA Astrophysics Data System (ADS)

Hart, S. R.; Workman, R. K.; Coetzee, M.; Blusztajn, J. S.; Ball, L.; Johnson, K. T.

2002-12-01

The Samoan hotspot has produced a chain of volcanism stretching from the island of Savai'i in the west to the presently active "leading-edge" volcano, Vailulu'u, in the east. An alignment of seamounts and submarine banks extending west of Savai'i is believed to be the earliest expression of the hotspot (Johnson, 1986). In 2001, we sampled the oldest shield exposures on Savai'i and western Upolu; these, and samples from the western banks Lalla Rookh, Combe and Alexa, have been analyzed for Pb isotopes using a new high precision Pb technique developed on the NEPTUNE ICP/Multi-Collector at W.H.O.I. Pb samples were doped with the NBS 997 thallium standard, with Pb/Tl ratios between 4 and 10; mass discrimination was adjusted to 205Tl/203Tl=2.387075 using an exponential fractionation law. Each run consisted of 35 cycles (16 s each) at an uptake rate of 0.13 μl/min (~12 minutes per run). The abundance sensitivity of the NEPTUNE is 2 ppm downmass and 1 ppm upmass; tailing at mass 204 from Tl is therefore ~30 ppm for 204Pb in a Pb/Tl = 4 solution. This can be adequately accounted for by careful selection of off-peak baseline positions. Beyond this effect, there is no dependence of Pb isotope ratios on Pb/Tl, over the range from 4-10. The correction on 204Pb for 204Hg was also minimal (20-30 ppm) and quite stable. Thirty runs of the NBS 981 standard (200 ppb solution, 12 different days over a period of 5 months) produced results very similar to the best TIMS data, with excellent external reproducibility: 206Pb/204Pb=19.9309(90), 207Pb/204Pb=15.4843(98), 208Pb/204Pb=36.6756(112) (in parenthesis, +/- 2σ in ppm). Similar external reproducibility was achieved for the Samoan basalt samples (duplicate runs on different days on solution splits from a single chemistry: +/- 2σ ppm = 101, 89 and 117, respectively). Over this time period, the variability of Tl mass bias was very small (+/- 130 ppm standard deviation). The only significant pitfall we have encountered is a memory effect that we believe is related to re-sputtering of prior Pb's (particularly the unradiogenic 981's) from the cones. Our results from the Savai'i and Upolu shields form well-defined linear arrays, separate but parallel in 208/204-206/204 and intersecting in 207/204-206/204; the Savai'i array in the latter plot is unusual in that it has a negative slope. The Upolu shield data is distinct from the Upolu post-erosional field; however, the Savai'i shield is only marginally resolvable from the Savai'i post-erosional field. The Pb data from Lalla Rookh and Combe banks are firmly ensconced in the general field of Samoan Pb's; the data from Alexa Bank, while outside the Samoan field, is aligned with it and arguably "Samoan". This new data extend the evidence of Samoan hotspot activity back in time by at least 600 km, and possibly 1400 km (9-20 m.y. at 7cm/year plate velocity).

Aviation Maintenance Technology. Airframe. A204. Aircraft Welding. Instructor Material.

ERIC Educational Resources Information Center

Oklahoma State Board of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This teacher's guide is designed to aid teachers in leading students through a module on aircraft welding on airframes. The module contains four units that cover the following topics: (1) gas welding and cutting; (2) brazing and soldering; (3) shielded metal arc welding; and (4) gas tungsten arc welding. Each unit follows a standardized format…

Determined Initial lead for South Of Isua (SOI) terrain suggests a single homogeneous source for it and possibly other archaean rocks

NASA Astrophysics Data System (ADS)

Tera, F.

2011-12-01

A Thorogenic-Uranogenic Lead Isotope Plane (TULIP), which entails plotting 206/208 (or its reverse) vs 207/208 (or its reverse), was applied to the Pb data on South of Isua (SOI) by Kamber et al., (1). When the data on 20 samples of these rocks and feldspars are plotted in pairs (each pair is a rock and its feldspar) on TULIP, they fall on 10 mixing lines that converge on a single spot (Fig. 1). This is the end member initial lead (EMIL). The 206/208 & 207/208 so determined are 0.3675 and 0.43525, respectively. From these values one calculates 207/206 = 1.1843 ± 0.0007, for EMIL. This pattern requires either: A) each pair has a singular kappa, K = 232Th/238U, different from others, or B) a pair's in situ decay Pb was homogenized in recent times. On 204/206 vs 207/206 diagram, the whole rocks of SOI define a 3.776 Ga isochron (2). From this and EMIL's 207/206, one obtains: 206/204 = 10.977, 207/204 = 12.974; and 208/204 = 29.756. This singularity of initial Pb contrasts with a deduced variability by the original authors (1). EMIL's radiogenic *(207/206) = 1.6220, gives a single-stage age = 5.9 Ga, indicating inapplicability of its evolution in one stage. Also, the μ calculated from 238U-206Pb for the single stage is different from that inferred from 235U-207Pb, confirming disqualification of this scenario. Reconciliation of the two decay schemes necessitates assumption of EMIL evolution in a minimum of two stages. Starting at 4.563 Ga, five scenarios were assumed: First stage ends and second starts at 4.55, 4.54, 4.53, 4.52 or 4.51 Ga. Second stages end at 3.776 Ga. The calculated μ1 for the first stage are 106, 59.5, 44.6, 36.3 and 30.9 respectively. For μ2 the change is limited, from 5.45 to 5.28. Only an average calculated K for both stages is possible. For the five outlined scenarios it ranges from 1.118 to 1.111. Earlier, Tera (3) observed that initial Pb of the oldest terrestrial reservoir requires evolution in two stages. There too μ1 >> μ2. Data on other rocks from Isua Greenstone Belt (1) and Amîtsoq gneiss (4) fall inside the TULIP triangle of SOI, suggesting potential derivation of these Archaean rocks from the same homogeneous source.

Isotopic identification of natural vs. anthropogenic lead sources in marine sediments from the inner Ría de Vigo (NW Spain).

PubMed

Álvarez-Iglesias, P; Rubio, B; Millos, J

2012-10-15

San Simón Bay, the inner part of the Ría de Vigo (NW Spain), an area previously identified as highly polluted by Pb, was selected for the application of Pb stable isotope ratios as a fingerprinting tool in subtidal and intertidal sediment cores. Lead isotopic ratios were determined by inductively coupled plasma mass spectrometry on extracts from bulk samples after total acid digestion. Depth-wise profiles of (206)Pb/(207)Pb, (206)Pb/(204)Pb, (207)Pb/(204)Pb, (208)Pb/(204)Pb and (208)Pb/(207)Pb ratios showed, in general, an upward decrease for both intertidal and subtidal sediments as a consequence of the anthropogenic activities over the last century, or centuries. Waste channel samples from a nearby ceramic factory showed characteristic Pb stable isotope ratios different from those typical of coal and petrol. Natural isotope ratios from non-polluted samples were established for the study area, differentiating sediments from granitic or schist-gneiss sources. A binary mixing model employed on the polluted samples allowed estimating the anthropogenic inputs to the bay. These inputs represented between 25 and 98% of Pb inputs in intertidal samples, and 9-84% in subtidal samples, their contributions varying with time. Anthropogenic sources were apportioned according to a three-source model. Coal combustion-related emissions were the main anthropogenic source Pb to the bay (60-70%) before the establishment of the ceramic factory in the area (in the 1970s) which has since constituted the main source (95-100%), followed by petrol-related emissions. The Pb inputs history for the intertidal area was determined for the 20th century, and, for the subtidal area, the 19th and 20th centuries. Copyright © 2012 Elsevier B.V. All rights reserved.

18 CFR 385.204 - Applications (Rule 204).

Code of Federal Regulations, 2010 CFR

2010-04-01

....204 Applications (Rule 204). Any person seeking a license, permit, certification, or similar authorization or permission, must file an application to obtain that authorization or permission. ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Applications (Rule 204...

40 CFR 1065.703 - Distillate diesel fuel.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 1 Cetane Number 40-50 40-50 40-50 ASTM D613-05. Distillation range: Initial boiling point °C 171-204 171-204 171-204 ASTM D86-07a. 10 pct. point 204-238 204-238 204-238 50 pct. point 243-282 243-282 243...-37 ASTM D4052-96e01. Total sulfur, ultra low sulfur mg/kg 7-15 See 40 CFR 80.580. Total sulfur, low...

Lead isotope compositions of Late Cretaceous and early Tertiary igneous rocks and sulfide minerals in Arizona: Implications for the sources of plutons and metals in porphyry copper deposits

USGS Publications Warehouse

Bouse, R.M.; Ruiz, J.; Titley, S.R.; Tosdal, R.M.; Wooden, J.L.

1999-01-01

Porphyry copper deposits in Arizona are genetically associated with Late Cretaceous and early Tertiary igneous complexes that consist of older intermediate volcanic rocks and younger intermediate to felsic intrusions. The igneous complexes and their associated porphyry copper deposits were emplaced into an Early Proterozoic basement characterized by different rocks, geologic histories, and isotopic compositions. Lead isotope compositions of the Proterozoic basement rocks define, from northwest to southeast, the Mojave, central Arizona, and southeastern Arizona provinces. Porphyry copper deposits are present in each Pb isotope province. Lead isotope compositions of Late Cretaceous and early Tertiary plutons, together with those of sulfide minerals in porphyry copper deposits and of Proterozoic country rocks, place important constraints on genesis of the magmatic suites and the porphyry copper deposits themselves. The range of age-corrected Pb isotope compositions of plutons in 12 Late Cretaceous and early Tertiary igneous complexes is 206Pb/204Pb = 17.34 to 22.66, 207Pb/204Pb = 15.43 to 15.96, and 208Pb/204Pb = 37.19 to 40.33. These Pb isotope compositions and calculated model Th/U are similar to those of the Proterozoic rocks in which the plutons were emplaced, thereby indicating that Pb in the younger rocks and ore deposits was inherited from the basement rocks and their sources. No Pb isotope differences distinguish Late Cretaceous and early Tertiary igneous complexes that contain large economic porphyry copper deposits from less rich or smaller deposits that have not been considered economic for mining. Lead isotope compositions of Late Cretaceous and early Tertiary plutons and sulfide minerals from 30 metallic mineral districts, furthermore, require that the southeastern Arizona Pb province be divided into two subprovinces. The northern subprovince has generally lower 206Pb/204Pb and higher model Th/U, and the southern subprovince has higher 206Pb/204Pb and lower model Th/U. These Pb isotope differences are inferred to result from differences in their respective post-1.7 Ga magmatic histories. Throughout Arizona, Pb isotope compositions of Late Cretaceous and early Tertiary plutons and associated sulfide minerals are distinct from those of Jurassic plutons and also middle Tertiary igneous rocks and sulfide minerals. These differences most likely reflect changes in tectonic setting and magmatic sources. Within Late Cretaceous and early Tertiary igneous complexes that host economic porphyry copper deposits, there is commonly a decrease in Pb isotope composition from older to younger plutons. This decrease in Pb isotope values with time suggests an increasing involvement of crust with lower U/Pb than average crust in the source(s) of Late Cretaceous and early Tertiary magmas. Lead isotope compositions of the youngest porphyries in the igneous complexes are similar to those in most sulfide minerals within the associated porphyry copper deposit. This Pb isotope similarity argues for a genetic link between them. However, not all Pb in the sulfide minerals in porphyry copper deposits is magmatically derived. Some sulfide minerals, particularly those that are late stage, or distal to the main orebody, or in Proterozoic or Paleozoic rocks, have elevated Pb isotope compositions displaced toward the gross average Pb isotope composition of the local country rocks. The more radiogenic isotopic compositions argue for a contribution of Pb from those rocks at the site of ore deposition. Combining the Pb isotope data with available geochemical, isotopic, and petrologic data suggests derivation of the young porphyry copper-related plutons, most of their Pb, and other metals from a hybridized lower continental crustal source. Because of the likely involvement of subduction-related mantle-derived basaltic magma in the hybridized lower crustal source, an indiscernible mantle contribution is probable in the porphyry magmas. Clearly, in addition

Anomalous Lead Isotopic Composition of Galena and Age of Altered Uranium Minerals: a Case study of Chauli Deposits, Chatkal-Qurama District, Uzbekistan

NASA Astrophysics Data System (ADS)

Chernyshev, I. V.; Golubev, V. N.; Chugaev, A. V.

2017-11-01

The enrichment of lead isotopic composition of nonuranium minerals, in the first place galena in 206Pb and 207Pb, as compared to common lead is a remarkable feature of uranium deposits. The study of such lead isotopic composition anomalous in 206Pb and 207Pb in uranium minerals provides an opportunity for not only identification of superimposed processes resulting in transformation of uranium ores during deposit history but also calculation of age of these processes under certain model assumptions. Galena from the Chauli deposit in the Chatkal-Qurama district, Uzbekistan, a typical representative of hydrothermal uranium deposits associated with domains of Phanerozoic continental volcanism, has been examined with the highprecision (±0.02%) MC-ICP-MS method. Twenty microsamples of galena were taken from polished sections. Six of them are galena hosted in carbonate adjacent to pitchblende spherulites or filling thin veinlets (approximately 60 μm) cutting pitchblende. Isotopically anomalous lead with 206Pb/204Pb and 207Pb/204Pb values reaching 20.462 and 15.743, respectively, has been found in these six microsamples in contrast to another fourteen in which the Pb-Pb characteristics are consistent with common lead. On the basis of these data and with account for the 292 ± 2 Ma age for the Chauli deposit, the age of epigenetic transformation of uranium ores of this deposit has been estimated. During this process, radiogenic lead partly lost from pitchblende was captured into galena. The obtained date is 170 Ma. In the Chatkal-Qurama district, these epigenetic processes are apparently caused by the interaction of uranium minerals with activated underground water under tectonic activity and relief transformation, which took place from the post-Permian (i.e., after the Chauli formation) to the Jurassic period.

40 CFR Appendix I to Part 204 - Appendix I to Part 204

Code of Federal Regulations, 2011 CFR

2011-07-01

... Part 204 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS NOISE EMISSION STANDARDS FOR CONSTRUCTION EQUIPMENT Pt. 204, App. I Appendix I to Part 204 Table I... Noise Data Sheet Test report number: Subject: Manufacturer: Model: Serial No.: Rated speed: Rpm: Rated...

41 CFR 50-204.2 - General safety and health standards.

Code of Federal Regulations, 2013 CFR

2013-07-01

... health standards. 50-204.2 Section 50-204.2 Public Contracts and Property Management Other Provisions Relating to Public Contracts PUBLIC CONTRACTS, DEPARTMENT OF LABOR 204-SAFETY AND HEALTH STANDARDS FOR FEDERAL SUPPLY CONTRACTS General Safety and Health Standards § 50-204.2 General safety and health...

40 CFR Appendix I to Part 204 - Appendix I to Part 204

Code of Federal Regulations, 2010 CFR

2010-07-01

... Part 204 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS NOISE EMISSION STANDARDS FOR CONSTRUCTION EQUIPMENT Pt. 204, App. I Appendix I to Part 204 Table I... Noise Data Sheet Test report number: Subject: Manufacturer: Model: Serial No.: Rated speed: Rpm: Rated...

17 CFR 204.34 - Employee response.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Employee response. 204.34... DEBT COLLECTION Salary Offset § 204.34 Employee response. (a) Introduction. An employee must respond to... ways discussed in § 204.34, Employee response, and § 204.35, Petition for pre-offset hearing. Where...

Monitoring steel bridge renovation using lead isotopic tracing.

PubMed

Salome, Fred; Gulson, Brian; Chiaradia, Massimo; Davis, Jeffrey; Morris, Howard

2017-05-01

Monitoring removal of lead (Pb) paint from steel structures usually involves analysis of environmental samples for total lead and determination of blood Pb levels of employees involved in the Pb paint removal. We used high precision Pb isotopic tracing for a bridge undergoing Pb paint removal to determine if Pb in the environmental and blood samples originated from the bridge paint. The paint system on the bridge consisted of an anti-corrosive red Pb primer top-coated with a Micaceous Iron Oxide (MIO) alkyd. Analysis of the red Pb primer gave uniform isotopic ratios indicative of Pb from the geologically-ancient Broken Hill mines in western New South Wales, Australia. Likewise waste abrasive material, as anticipated, had the same isotopic composition as the paint. The isotopic ratios for other samples lay on 2 separate linear arrays on a 207 Pb/ 204 Pb versus 206 Pb/ 204 Pb diagram, one largely defined by gasoline and the majority of the ambient air data, and the other by data for one sample each of gasoline and ambient air and underwater sediments. Isotopic ratios in background ambient air samples for the project were characteristic of leaded gasoline. Air sampling during paint removal showed a contribution of paint Pb ranging from about 20 to 40%. Isotopic ratios in the blood of 8 employees prior to the commencement of work showed that 6 of these had been previously exposed to the Broken Hill Pb possibly from earlier bridge paint removal projects. One subject appeared to have increased exposure to Pb probably from the paint renovations. Copyright © 2017 Elsevier Ltd. All rights reserved.

A 300 year history of lead contamination in northern French Alps reconstructed from distant lake sediment records.

PubMed

Arnaud, F; Revel-Rolland, M; Bosch, D; Winiarski, T; Desmet, M; Tribovillard, N; Givelet, N

2004-05-01

Lead concentrations and isotopic ratios were measured along two well-dated sediment cores from two distant lakes: Anterne (2100 m a.s.l.) and Le Bourget (270 m a.s.l.), submitted to low and high direct human impact and covering the last 250 and 600 years, respectively. The measurement of lead in old sediment samples (>3000 BP) permits, in using mixing-models, the determination of lead concentration, flux and isotopic composition of purely anthropogenic origin. We thus show that since ca. 1800 AD the regional increase in lead contamination was mostly driven by coal consumption ((206)Pb/(207)Pb approximately 1.17-1.19; (206)Pb/(204)Pb approximately 18.3-18.6), which peaks around 1915 AD. The increasing usage of leaded gasoline, introduced in the 1920s, was recorded in both lakes by increasing Pb concentrations and decreasing Pb isotope ratios. A peak around 1970 ((206)Pb/(207)Pb approximately 1.13-1.16; (206)Pb/(204)Pb approximately 17.6-18.0) corresponds to the worldwide recorded leaded gasoline maximum of consumption. The 1973 oil crisis is characterised by a drastic drop of lead fluxes in both lakes (from approximately 35 to <20 mg cm(-2) yr(-1)). In the late 1980s, environmental policies made the Lake Anterne flux drop to pre-1900 values (<10 mg cm(-2) yr(-1)) while Lake Le Bourget is always submitted to an important flux (approximately 25 mg cm(-2) yr(-1)). The good match of our distant records, together and with a previously established series in an ice core from Mont Blanc, provides confidence in the use of sediments as archives of lead contamination. The integration of the Mont Blanc ice core results from Rosman et al. with our data highlights, from 1990 onward, a decoupling in lead sources between the high elevation sites (Lake Anterne and Mont Blanc ice core), submitted to a mixture of long-distance and regional contamination and the low elevation site (Lake Le Bourget), where regional contamination is predominant.

miR-204-5p suppresses cell proliferation by inhibiting IGFBP5 in papillary thyroid carcinoma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Lianyong; Wang, Jingnan; Li, Xiangqi

2015-02-20

microRNAs (miRNAs) are frequently dysregulated in human malignancies. It was recently shown that miR-204-5p is downregulated in papillary thyroid carcinoma (PTC); however, the functional significance of this observation is not known. This study investigated the role of miR-204-5p in PTC. Overexpressing miR-204-5p suppressed PTC cell proliferation and induced cell cycle arrest and apoptosis. The results of a luciferase reporter assay showed that miR-204-5p can directly bind to the 3′ untranslated region (UTR) of insulin-like growth factor-binding protein 5 (IGFBP5) mRNA, and IGFBP5 overexpression partially reversed the growth-inhibitory effects of miR-204-5p. These results indicate that miR-204-5p acts as a tumor suppressormore » in PTC by regulating IGFBP5 expression and that miR-204-5p can potentially serve as an antitumorigenic agent in the treatment of PTC. - Highlights: • miR-204-5p expression is downregulated in PTC tissues and cell lines. • miR-204-5p suppresses proliferation and promotes apoptosis in PTC cells. • miR-204-5p suppresses IGFBP5 expression by direct binding to the 3′-UTR. • IGFBP5 overexpression reverses the effects of miR-204-5p.« less

48 CFR 243.204-70-5 - Exceptions.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT CONTRACT MODIFICATIONS Change Orders 243.204-70-5 Exceptions. (a) The limitations in 243.204-70-2, 243.204-70-3, and 243.204-70-4 do not apply to unpriced change orders... change orders for ship construction and ship repair. (c) The head of the agency may waive the limitations...

48 CFR 243.204-70-5 - Exceptions.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT CONTRACT MODIFICATIONS Change Orders 243.204-70-5 Exceptions. (a) The limitations in 243.204-70-2, 243.204-70-3, and 243.204-70-4 do not apply to unpriced change orders... change orders for ship construction and ship repair. (c) The head of the agency may waive the limitations...

miR-204 inhibits angiogenesis and promotes sensitivity to cetuximab in head and neck squamous cell carcinoma cells by blocking JAK2-STAT3 signaling.

PubMed

Wu, Qingwei; Zhao, Yingying; Wang, Peihua

2018-03-01

This study aims to investigate the roles of miR-204 in tumor angiogenesis of head and neck squamous cell carcinoma (HNSCC). Here, we found that miR-204 level was reduced in HNSCC tissues relative to that in normal adjacent tissues. Overexpression of miR-204 promoted tumor angiogenesis in HNSCC cells. Mechanistically, JAK2 was identified as a direct target of miR-204, and miR-204 overexpression blocked JAK2/STAT3 pathway. Moreover, overexpression of JAK2 attenuated the inhibition of miR-204 on tumor angiogenesis of HNSCC. Furthermore, overexpression of miR-204 enhanced sensitivity of cetuximab in HNSCC cells, this effect was attenuated by JAK2 overexpression too. Importantly, JAK2 expression was negatively correlated with miR-204 level in HNSCC tissues. Therefore, miR-204 acts as a tumor suppressor by blocking JAK2/STAT3 pathway in HNSCC cells. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

Lead isotope studies of the Guerrero composite terrane, west-central Mexico: implications for ore genesis

NASA Astrophysics Data System (ADS)

Potra, Adriana; Macfarlane, Andrew W.

2014-01-01

New thermal ionization mass spectrometry and multi-collector inductively coupled plasma mass spectrometry Pb isotope analyses of three Cenozoic ores from the La Verde porphyry copper deposit located in the Zihuatanejo-Huetamo subterrane of the Guerrero composite terrane are presented and the metal sources are evaluated. Lead isotope ratios of 3 Cenozoic ores from the El Malacate and La Esmeralda porphyry copper deposits located in the Zihuatanejo-Huetamo subterrane and of 14 ores from the Zimapan and La Negra skarn deposits from the adjoining Sierra Madre terrane are also presented to look for systematic differences in the lead isotope trends and ore metal sources among the proposed exotic tectonostratigraphic terranes of southern Mexico. Comparison among the isotopic signatures of ores from the Sierra Madre terrane and distinct subterranes of the Guerrero terrane supports the idea that there is no direct correlation between the distinct suspect terranes of Mexico and the isotopic signatures of the associated Cenozoic ores. Rather, these Pb isotope patterns are interpreted to reflect increasing crustal contribution to mantle-derived magmas as the arc advanced eastward onto a progressively thicker continental crust. The lead isotope trend observed in Cenozoic ores is not recognized in the ores from Mesozoic volcanogenic massive sulfide and sedimentary exhalative deposits. The Mesozoic ores formed prior to the amalgamation of the Guerrero composite terrane to the continental margin, which took place during the Late Cretaceous, in intraoceanic island arc and intracontinental marginal basin settings, while the Tertiary deposits formed after this event in a continental arc setting. Lead isotope ratios of the Mesozoic and Cenozoic ores appear to reflect these differences in tectonic setting of ore formation. Most Pb isotope values of ores from the La Verde deposit (206Pb/204Pb = 18.674-18.719) are less radiogenic than those of the host igneous rocks, but plot within the field defined by the Huetamo Sequence, suggesting that these ores may also contain metals from the sedimentary rocks. The Pb isotope ratios of ore samples from the Zimapan deposit (206Pb/204Pb = 18.771-18.848) are substantially higher than the whole-rock Pb isotope compositions of the basement rocks. The similarity of ore Pb to igneous rock Pb in the Zimapan district (206Pb/204Pb = 18.800-18.968) may indicate that the proximal source of ore metals in the hydrothermal system was the igneous activity.

40 CFR 421.93 - Effluent limitations guidelines representing the degree of effluent reduction attainable by the...

Code of Federal Regulations, 2011 CFR

2011-07-01

... Metallurgical Acid Plants Subcategory § 421.93 Effluent limitations guidelines representing the degree of...—Metallurgical Acid Plant—BAT Effluent Limitations Pollutant or pollutant property Maximum for any 1 day Maximum... 1.584 Cadmium 0.511 0.204 Copper 3.269 1.558 Lead 0.715 0.332 Zinc 2.605 1.073 Fluoride 1 89.390 50...

40 CFR 421.93 - Effluent limitations guidelines representing the degree of effluent reduction attainable by the...

Code of Federal Regulations, 2010 CFR

2010-07-01

... Metallurgical Acid Plants Subcategory § 421.93 Effluent limitations guidelines representing the degree of...—Metallurgical Acid Plant—BAT Effluent Limitations Pollutant or pollutant property Maximum for any 1 day Maximum... 1.584 Cadmium 0.511 0.204 Copper 3.269 1.558 Lead 0.715 0.332 Zinc 2.605 1.073 Fluoride 1 89.390 50...

48 CFR 46.204 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false [Reserved] 46.204 Section 46.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Quality Requirements 46.204 [Reserved] ...

8 CFR 204.8 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false [Reserved] 204.8 Section 204.8 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRANT PETITIONS Immigrant Visa Petitions § 204.8 [Reserved] ...

40 CFR 243.204 - Collection management.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Collection management. 243.204 Section 243.204 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES... and Recommended Procedures § 243.204 Collection management. ...

40 CFR 243.204 - Collection management.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Collection management. 243.204 Section 243.204 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES... and Recommended Procedures § 243.204 Collection management. ...

40 CFR 243.204 - Collection management.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Collection management. 243.204 Section 243.204 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES... and Recommended Procedures § 243.204 Collection management. ...

40 CFR 243.204 - Collection management.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Collection management. 243.204 Section 243.204 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES... and Recommended Procedures § 243.204 Collection management. ...

40 CFR 243.204 - Collection management.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Collection management. 243.204 Section 243.204 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES... and Recommended Procedures § 243.204 Collection management. ...

Origin of the Red Dog Zn-Pb-Ag deposits, Brooks Range, Alaska: Evidence from regional Pb and Sr isotope sources

USGS Publications Warehouse

Ayuso, R.A.; Kelley, K.D.; Leach, D.L.; Young, L.E.; Slack, J.F.; Wandless, G.; Lyon, A.M.; Dillingham, J.L.

2004-01-01

Pb and Sr isotope data were obtained on the shale-hosted Zn-Pb-Ag Red Dog deposits (Qanaiyaq, Main, Aqqaluk, and Paalaaq), other shale-hosted deposits near Red Dog, and Zn-Pb-Ag sulfide and barite deposits in the western and central Brooks Range. The Red Dog deposits and other shale-hosted Zn-Pb-Ag deposits near Red Dog are hosted in the Mississippian Kuna Formation, which is underlain by a sequence of marine-deltaic clastic rocks of the Upper Devonian to Lower Mississippian Endicott Group. Ag-Pb-Zn vein-breccias are found in the Endicott Group. Galena formed during the main mineralization stages in the Red Dog deposits and from the Anarraaq and Wulik deposits have overlapping Pb isotope compositions in the range 206Pb/204Pb = 18.364 to 18.428, 207Pb/204Pb = 15.553 to 15.621, and 208Pb/204Pb = 38.083 to 38.323. Galena and sphalerite formed during the main ore-forming stages in the Red Dog deposits define a narrow field on standard uranogenic and thorogenic Pb isotope diagrams. Lead in sulfides of the Red Dog district is less radiogenic (238U/204Pb: ?? = 9.51-9.77) than is indicated by the average crustal lead evolution model (?? = 9.74), a difference consistent with a long history of evolution at low ratios of ?? before the Carboniferous. The homogeneous regional isotopic reservoir of Pb may indicate large-scale transport and leaching of minerals with various ?? ratios and Th/Pb ratios. Younger and genetically unrelated fluids did not significantly disturb the isotopic compositions of galena and sphalerite after the main mineralization event in the Red Dog district. Some pyrite shows evidence of minor Pb remobilization. The overall lead isotope homogeneity in the shale-hosted massive sulfide deposits is consistent with three types of control: a homogeneous regional source, mixing of lead during leaching of a thick sedimentary section and fluid transport, or mixing at the site of deposition. Isotopic variability of the hydrothermal fluids, as represented by galena in the Red Dog district, appears to be consistent with a simple mixing system. Evidence indicates that galena was deposited from largely similar hydrothermal solutions throughout the Red Dog district. A shared regional isotopic reservoir is also supported by the correspondence of Pb isotope compositions of galena in deposits of the Red Dog district and galena in clastic rocks (vein-breccias). Leaching of metals and progressive extraction of radiogenic lead from the clastic rocks in the Endicott Group may account for the trend of increasing 206Pb/204Pb in galena of the Red Dog district. Galena in the Red Dog deposits is unlikely to have been derived entirely from the same isotopic reservoir as that represented by the lead in the Kuna Formation or from the igneous rocks in the Red Dog district. Sr isotope data for barite, calcite, and witherite from the Red Dog deposits are compared with data from regional barite that is associated with sulfides and from barite in sulfide-poor occurrences. Fluids with heterogeneous Sr isotope signatures are indicated. Barite in the Main deposit extends to higher ratios of 87Sr/86Sr (0.709034-0.709899) than barite in the Anarraaq deposit (0.708615-0.709256). All barite is more radiogenic than Carboniferous seawater. Other Mississippian(?) shale-hosted deposits and mineral occurrences containing barite in the Red Dog district and barite in regional occurrences east of Red Dog in the western and central Brooks Range also have heterogeneous 87Sr/86Sr ratios. Carbonate (87Sr/86Sr = 0.710319-0.713637) and witherite (87 Sr/86 Sr = 0.710513) in the Main deposit are more radiogenic than barite. In contrast, carbonate (87Sr/86Sr = 0.708196-0.709740) intergrown with massive sulfides at Anarraaq has isotopic compositions similar to that of barite. Paragenetic and isotop ic studies suggest that early barite is similar to barite typically formed in cold seeps along continental margins. This early fine-grained barite formed before the main mineralizat

48 CFR 204.7301 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Definitions. 204.7301 Section 204.7301 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Export-Controlled Items 204.7301 Definitions. Export...

48 CFR 204.7301 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Definitions. 204.7301 Section 204.7301 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Export-Controlled Items 204.7301 Definitions. Export...

48 CFR 204.7301 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Definitions. 204.7301 Section 204.7301 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Export-Controlled Items 204.7301 Definitions. Export...

48 CFR 53.204 - Administrative matters.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Administrative matters. 53.204 Section 53.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.204 Administrative matters. ...

48 CFR 53.204 - Administrative matters.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Administrative matters. 53.204 Section 53.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.204 Administrative matters. ...

48 CFR 53.204 - Administrative matters.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Administrative matters. 53.204 Section 53.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.204 Administrative matters. ...

48 CFR 53.204 - Administrative matters.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Administrative matters. 53.204 Section 53.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.204 Administrative matters. ...

48 CFR 53.204 - Administrative matters.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Administrative matters. 53.204 Section 53.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.204 Administrative matters. ...

Lead isotope ratio measurements as indicators for the source of lead poisoning in Mute swans (Cygnus olor) wintering in Puck Bay (northern Poland).

PubMed

Binkowski, Łukasz J; Meissner, Włodzimierz; Trzeciak, Marta; Izevbekhai, Kelvin; Barker, James

2016-12-01

Lead (Pb) poisoning is most commonly linked amongst anthropogenically-caused deaths in waterfowl and this is often associated with hunting and fishing activities. However, the exact identification of the source may be difficult with commonly-used techniques. We have studied isotope ratios using Inductively-Coupled Plasma Mass Spectrometry (ICP-MS) to investigate the source of Pb in the blood of Mute swans (n = 49) wintering in northern Poland. We compared the values of isotopic ratios from blood and ammunition pellets available on the Polish market. The mean Pb concentrations found was 0.241 μg/g (w/w) and nearly half of the blood specimens had elevated Pb levels (higher than the cited 0.23 μg/g w/w threshold of poisoning). Only the mean 208/206 Pb isotope ratio was similar in blood and pellet samples. Mean ratios of isotopes 206/204, 206/207 and 208/207 in swans' blood and in pellets differed significantly. Moreover, coefficients of variation were higher in blood samples than in pellets. These discrepancies and significant differences in abundance of 204 Pb and 207 Pb isotopes in both materials indicated that pellets available today on the Polish market were not the source of Pb in the blood of Mute swans wintering in northern Poland. Copyright © 2016 Elsevier Ltd. All rights reserved.

Production of bismuth-204 for medical use

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kinsley, M.T.; Lebowitz, E.; Baranosky, J.

1973-11-01

A method is described for producing practical quantities of highpuriti, / sup 204/Bi by, the /sup 206/Pb(p,3n)/sup 204/Bi reaction. A simple elec trolytic separation method with good yield has been developed. The cross section for the above reaction was calculated for 32,MeV protons. Decay data for /supb 204/Bi-/ sup 204m/Pb equilibrium samples are also reported. (auth)

Factors controlling elevated lead concentrations in water samples from aquifer systems in Florida

USGS Publications Warehouse

Katz, B.G.; Bullen, M.P.; Bullen, T.D.; Hansard, Paul

1999-01-01

Concentrations of total lead (Pb) and dissolved Pb exceeded the U.S. Environmental Protection Agency action level of 15 micrograms per liter (mg/L) in approximately 19 percent and 1.3 percent, respectively, of ground-water samples collected during 1991-96 from a statewide network of monitoring wells designed to delineate background water quality of Florida's major aquifer systems. Differences in total Pb concentrations among aquifer systems reflect the combined influence of anthropogenic sources and chemical conditions in each system. A highly significant (p<0.001) difference in median total Pb concentrations was found for water samples from wells with water-level recording devices that contain Pb-counterweights (14 mg/L) compared to non-recorder wells (2 mg/L). Differences between total Pb concentrations for recorder and non-recorder wells are even more pronounced when compared for each aquifer system. The largest differences for recorder status are found for the surficial aquifer system, where median total Pb concentrations are 44 and 2.4 mg/L for recorder wells and non-recorder wells, respectively. Leaching of Pb from metal casing materials is another potential source of Pb in ground water samples. Median total Pb concentrations in water samples from the surficial, intermediate, and Floridan aquifer systems are higher from recorder wells cased with black iron than for recorder wells with steel and PVC casing material. Stable isotopes of Pb were used in this study to distinguish between anthropogenic and natural sources of Pb in ground water, as Pb retains the isotopic signature of the source from which it is derived. Based on similarities between slopes and intercepts of trend lines for various sample types (plots of 206Pb/204Pb versus 208Pb/204Pb and 207Pb/204Pb versus 208Pb/204Pb) the predominant source of total Pb in water samples from the surficial aquifer system is corrosion of Pb counterweights. It is likely that only ground-water samples, not the aquifer, were contaminated with elevated Pb concentations. Pb-isotopic ratios of water from the Floridan aquifer system plot between trend lines connecting the isotopic composition of Pb counterweights and the composition of acid leachates of material from the Floridan aquifer system, indicating that Pb in these waters most likely is a mixture of Pb derived from aquifer material and corrosion of Pb counterweights.

Levels and source apportionment of children's lead exposure: could urinary lead be used to identify the levels and sources of children's lead pollution?

PubMed

Cao, Suzhen; Duan, Xiaoli; Zhao, Xiuge; Wang, Beibei; Ma, Jin; Fan, Delong; Sun, Chengye; He, Bin; Wei, Fusheng; Jiang, Guibin

2015-04-01

As a highly toxic heavy metal, the pollution and exposure risks of lead are of widespread concern for human health. However, the collection of blood samples for use as an indicator of lead pollution is not always feasible in most cohort or longitudinal studies, especially those involving children health. To evaluate the potential use of urinary lead as an indicator of exposure levels and source apportionment, accompanying with environmental media samples, lead concentrations and isotopic measurements (expressed as (207)Pb/(206)Pb, (208)Pb/(206)Pb and (204)Pb/(206)Pb) were investigated and compared between blood and urine from children living in the vicinities of a typical coking plant and lead-acid battery factory. The results showed urinary lead might not be a preferable proxy for estimating blood lead levels. Fortunately, urinary lead isotopic measurements could be used as an alternative for identifying the sources of children's lead exposure, which coincided well with the blood lead isotope ratio analysis. Copyright © 2015 Elsevier Ltd. All rights reserved.

40 CFR 204.55 - Requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirements. 204.55 Section 204.55 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS NOISE EMISSION STANDARDS FOR CONSTRUCTION EQUIPMENT Portable Air Compressors § 204.55 Requirements. ...

40 CFR 204.55 - Requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirements. 204.55 Section 204.55 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS NOISE EMISSION STANDARDS FOR CONSTRUCTION EQUIPMENT Portable Air Compressors § 204.55 Requirements. ...

40 CFR 204.55 - Requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirements. 204.55 Section 204.55 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS NOISE EMISSION STANDARDS FOR CONSTRUCTION EQUIPMENT Portable Air Compressors § 204.55 Requirements. ...

48 CFR 39.204 - Exceptions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Exceptions. 39.204 Section 39.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Electronic and Information Technology 39.204 Exceptions. The...

48 CFR 39.204 - Exceptions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Exceptions. 39.204 Section 39.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Electronic and Information Technology 39.204 Exceptions. The...

48 CFR 39.204 - Exceptions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Exceptions. 39.204 Section 39.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Electronic and Information Technology 39.204 Exceptions. The...

48 CFR 39.204 - Exceptions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Exceptions. 39.204 Section 39.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Electronic and Information Technology 39.204 Exceptions. The...

23 CFR 450.204 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 23 Highways 1 2012-04-01 2012-04-01 false Definitions. 450.204 Section 450.204 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Statewide Transportation Planning and Programming § 450.204 Definitions. Except as otherwise...

23 CFR 450.204 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 23 Highways 1 2014-04-01 2014-04-01 false Definitions. 450.204 Section 450.204 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Statewide Transportation Planning and Programming § 450.204 Definitions. Except as otherwise...

23 CFR 450.204 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 23 Highways 1 2013-04-01 2013-04-01 false Definitions. 450.204 Section 450.204 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Statewide Transportation Planning and Programming § 450.204 Definitions. Except as otherwise...

48 CFR 49.204 - Deductions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Deductions. 49.204 Section 49.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TERMINATION OF CONTRACTS Additional Principles for Fixed-Price Contracts Terminated for Convenience 49.204...

23 CFR 450.204 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false Definitions. 450.204 Section 450.204 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Statewide Transportation Planning and Programming § 450.204 Definitions. Except as otherwise...

23 CFR 450.204 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false Definitions. 450.204 Section 450.204 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Statewide Transportation Planning and Programming § 450.204 Definitions. Except as otherwise...

49 CFR 172.204 - Shipper's certification.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Shipper's certification. 172.204 Section 172.204 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY... SECURITY PLANS Shipping Papers § 172.204 Shipper's certification. (a) General. Except as provided in...

48 CFR 1517.204 - Contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Contracts. 1517.204 Section 1517.204 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Options 1517.204 Contracts. The SCM may approve a...

48 CFR 2033.204 - Policy.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Policy. 2033.204 Section 2033.204 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL CONTRACTING REQUIREMENTS PROTESTS, DISPUTES, AND APPEALS Disputes and Appeals 2033.204 Policy. Final decisions of the NRC...

48 CFR 2033.204 - Policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Policy. 2033.204 Section 2033.204 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL CONTRACTING REQUIREMENTS PROTESTS, DISPUTES, AND APPEALS Disputes and Appeals 2033.204 Policy. Final decisions of the NRC...

48 CFR 2033.204 - Policy.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Policy. 2033.204 Section 2033.204 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL CONTRACTING REQUIREMENTS PROTESTS, DISPUTES, AND APPEALS Disputes and Appeals 2033.204 Policy. Final decisions of the NRC...

24 CFR 585.204 - Locational considerations.

Code of Federal Regulations, 2011 CFR

2011-04-01

... URBAN DEVELOPMENT COMMUNITY FACILITIES YOUTHBUILD PROGRAM Youthbuild Planning Grants § 585.204... 24 Housing and Urban Development 3 2011-04-01 2010-04-01 true Locational considerations. 585.204 Section 585.204 Housing and Urban Development Regulations Relating to Housing and Urban Development...

24 CFR 585.204 - Locational considerations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... URBAN DEVELOPMENT COMMUNITY FACILITIES YOUTHBUILD PROGRAM Youthbuild Planning Grants § 585.204... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Locational considerations. 585.204 Section 585.204 Housing and Urban Development Regulations Relating to Housing and Urban Development...

48 CFR 1253.204 - Administrative matters.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Administrative matters. 1253.204 Section 1253.204 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION CLAUSES AND FORMS FORMS Prescription of Forms 1253.204 Administrative matters. The following forms are...

48 CFR 1253.204 - Administrative matters.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Administrative matters. 1253.204 Section 1253.204 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION CLAUSES AND FORMS FORMS Prescription of Forms 1253.204 Administrative matters. The following forms are...

48 CFR 1253.204 - Administrative matters.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Administrative matters. 1253.204 Section 1253.204 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION CLAUSES AND FORMS FORMS Prescription of Forms 1253.204 Administrative matters. The following forms are...

48 CFR 1253.204 - Administrative matters.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Administrative matters. 1253.204 Section 1253.204 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION CLAUSES AND FORMS FORMS Prescription of Forms 1253.204 Administrative matters. The following forms are...

48 CFR 1253.204 - Administrative matters.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Administrative matters. 1253.204 Section 1253.204 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION CLAUSES AND FORMS FORMS Prescription of Forms 1253.204 Administrative matters. The following forms are...

48 CFR 204.802 - Contract files.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Contract files. 204.802 Section 204.802 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.802 Contract files. Official contract...

48 CFR 204.802 - Contract files.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Contract files. 204.802 Section 204.802 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.802 Contract files. Official contract...

48 CFR 204.802 - Contract files.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contract files. 204.802 Section 204.802 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.802 Contract files. Official contract...

48 CFR 204.802 - Contract files.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Contract files. 204.802 Section 204.802 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.802 Contract files. Official contract...

48 CFR 204.802 - Contract files.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Contract files. 204.802 Section 204.802 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.802 Contract files. Official contract...

48 CFR 1817.204 - Contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contracts. 1817.204 Section 1817.204 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Options 1817.204 Contracts. (e)(i) The 5...

5 CFR 362.204 - Development, evaluation, promotion, and certification.

Code of Federal Regulations, 2010 CFR

2010-01-01

... be placed, with full-time management and/or technical responsibilities consistent with the Fellow's... certification. 362.204 Section 362.204 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PRESIDENTIAL MANAGEMENT FELLOWS PROGRAM Program Administration § 362.204 Development, evaluation...

Sirtuin1 protects endothelial Caveolin-1 expression and preserves endothelial function via suppressing miR-204 and endoplasmic reticulum stress.

PubMed

Kassan, M; Vikram, A; Kim, Y R; Li, Q; Kassan, A; Patel, H H; Kumar, S; Gabani, M; Liu, J; Jacobs, J S; Irani, K

2017-02-09

Sirtuin1 (Sirt1) is a class III histone deacetylase that regulates a variety of physiological processes, including endothelial function. Caveolin1 (Cav1) is also an important determinant of endothelial function. We asked if Sirt1 governs endothelial Cav1 and endothelial function by regulating miR-204 expression and endoplasmic reticulum (ER) stress. Knockdown of Sirt1 in endothelial cells, and in vivo deletion of endothelial Sirt1, induced endothelial ER stress and miR-204 expression, reduced Cav1, and impaired endothelium-dependent vasorelaxation. All of these effects were reversed by a miR-204 inhibitor (miR-204 I) or with overexpression of Cav1. A miR-204 mimic (miR-204 M) decreased Cav1 in endothelial cells. In addition, high-fat diet (HFD) feeding induced vascular miR-204 and reduced endothelial Cav1. MiR-204-I protected against HFD-induced downregulation of endothelial Cav1. Moreover, pharmacologic induction of ER stress with tunicamycin downregulated endothelial Cav1 and impaired endothelium-dependent vasorelaxation that was rescued by overexpressing Cav1. In conclusion, Sirt1 preserves Cav1-dependent endothelial function by mitigating miR-204-mediated vascular ER stress.

Delivery of antagomiR204-conjugated gold nanoparticles from PLGA sheets and its implication in promoting osseointegration of titanium implant in type 2 diabetes mellitus.

PubMed

Liu, Xiangwei; Tan, Naiwen; Zhou, Yuchao; Wei, Hongbo; Ren, Shuai; Yu, Fan; Chen, Hui; Jia, Chengming; Yang, Guodong; Song, Yingliang

2017-01-01

Impaired osseointegration of the implant remains the big hurdle for dental implant therapy in diabetic patients. In this study, the authors first identified that miR204 was strikingly highly expressed in the bone mesenchymal stem cells (BMSCs) of diabetic rats. Forced expression of miR204 repressed the osteogenic potential of BMSCs, while inhibition of miR204 significantly increased the osteogenic capacity. Moreover, the miR204 inhibitor was conjugated with gold nanoparticles (AuNP-antagomiR204) and dispersed them in the poly(lactic-co-glycolic acid) (PLGA) solution. The AuNP-antagomiR204 containing PLGA solution was applied for coating the surface of titanium implant. Electron microscope revealed that an ultrathin sheet was formed on the surface of the implant, and the AuNPs were evenly dispersed in the coated PLGA sheet. Cellular experiments revealed that these encapsulated AuNP-antagomiR204 were able to be released from the PLGA sheet and uptaken by adherent BMSCs. In vivo animal study further confirmed that the AuNP-antagomiR204 released from PLGA sheet promoted osseointegration, as revealed by microcomputerized tomography (microCT) reconstruction and histological assay. Taken together, this study established that miR204 misexpression accounted for the deficient osseointegation in diabetes mellitus, while PLGA sheets aided the release of AuNP-antagomiR204, which would be a promising strategy for titanium implant surface functionalization toward better osseointegration.

WAVE2 targeting to phosphatidylinositol 3,4,5-triphosphate mediated by insulin receptor substrate p53 through a complex with WAVE2.

PubMed

Takahashi, Kazuhide; Suzuki, Katsuo

2010-11-01

Membrane targeting of WAVE2 along microtubules to phosphatidylinositol 3,4,5-triphosphate (PIP(3)) in response to an extracellular stimulus requires Rac1, Pak1, stathmin, and EB1. However, whether WAVE2 interacts directly with PIP(3) or not remains unclear. We demonstrate that insulin-like growth factor I (IGF-I) induces WAVE2 membrane targeting, accompanied by phosphorylation of Pak1 at serine 199/204 (Ser199/204) and stathmin at Ser38 in the inner cytoplasmic region. This is spatially independent of the membrane region where the IGF-I receptor (IGF-IR) is locally activated. WAVE2, phosphorylated Pak1, and phosphorylated stathmin located at the microtubule ends began to accumulate at the leading edge of cells in close proximity to PIP(3) that was produced in a phosphatidylinositol 3-kinase (PI 3-kinase)-dependent manner. The PIP(3)-beads binding assay revealed that insulin receptor substrate p53 (IRSp53) and actin rather than WAVE2 bound to PIP(3). IRSp53 constitutively associated with WAVE2 and these two proteins colocalized with PIP(3) at the leading edge after IGF-I stimulation. Suppression of IRSp53 expression by two independent small interfering RNAs (siRNAs) completely inhibited IGF-I-induced membrane targeting and local accumulation of WAVE2 at the leading edge of cells. We propose that IRSp53 constitutively forms a complex with WAVE2 and is crucial for membrane targeting followed by local accumulation of WAVE2 at the leading edge of cells through linking WAVE2 to PIP(3) that is produced near locally activated IGF-IR in response to IGF-I. Copyright (c) 2010 Elsevier Inc. All rights reserved.

7 CFR 22.204 - Rural development committees.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 1 2011-01-01 2011-01-01 false Rural development committees. 22.204 Section 22.204 Agriculture Office of the Secretary of Agriculture RURAL DEVELOPMENT COORDINATION Roles and Responsibilities of Federal Government § 22.204 Rural development committees. State rural development committees...

7 CFR 22.204 - Rural development committees.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 1 2010-01-01 2010-01-01 false Rural development committees. 22.204 Section 22.204 Agriculture Office of the Secretary of Agriculture RURAL DEVELOPMENT COORDINATION Roles and Responsibilities of Federal Government § 22.204 Rural development committees. State rural development committees...

9 CFR 204.5 - Indexes.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Indexes. 204.5 Section 204.5 Animals and Animal Products GRAIN INSPECTION, PACKERS AND STOCKYARDS ADMINISTRATION (PACKERS AND STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE ORGANIZATION AND FUNCTIONS Public Information § 204.5 Indexes...

9 CFR 204.7 - Appeals.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Appeals. 204.7 Section 204.7 Animals and Animal Products GRAIN INSPECTION, PACKERS AND STOCKYARDS ADMINISTRATION (PACKERS AND STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE ORGANIZATION AND FUNCTIONS Public Information § 204.7 Appeals. Any...

9 CFR 204.5 - Indexes.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Indexes. 204.5 Section 204.5 Animals and Animal Products GRAIN INSPECTION, PACKERS AND STOCKYARDS ADMINISTRATION (PACKERS AND STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE ORGANIZATION AND FUNCTIONS Public Information § 204.5 Indexes...

9 CFR 204.5 - Indexes.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Indexes. 204.5 Section 204.5 Animals and Animal Products GRAIN INSPECTION, PACKERS AND STOCKYARDS ADMINISTRATION (PACKERS AND STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE ORGANIZATION AND FUNCTIONS Public Information § 204.5 Indexes...

9 CFR 204.7 - Appeals.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Appeals. 204.7 Section 204.7 Animals and Animal Products GRAIN INSPECTION, PACKERS AND STOCKYARDS ADMINISTRATION (PACKERS AND STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE ORGANIZATION AND FUNCTIONS Public Information § 204.7 Appeals. Any...

9 CFR 204.7 - Appeals.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Appeals. 204.7 Section 204.7 Animals and Animal Products GRAIN INSPECTION, PACKERS AND STOCKYARDS ADMINISTRATION (PACKERS AND STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE ORGANIZATION AND FUNCTIONS Public Information § 204.7 Appeals. Any...

9 CFR 204.7 - Appeals.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Appeals. 204.7 Section 204.7 Animals and Animal Products GRAIN INSPECTION, PACKERS AND STOCKYARDS ADMINISTRATION (PACKERS AND STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE ORGANIZATION AND FUNCTIONS Public Information § 204.7 Appeals. Any...

9 CFR 204.2 - Organization.

Code of Federal Regulations, 2012 CFR

2012-01-01

... STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE ORGANIZATION AND FUNCTIONS Public Information § 204.2 Organization. (a) The Grain Inspection, Packers and Stockyards Administration (Packers and Stockyards Programs... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Organization. 204.2 Section 204.2...

9 CFR 204.2 - Organization.

Code of Federal Regulations, 2013 CFR

2013-01-01

... STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE ORGANIZATION AND FUNCTIONS Public Information § 204.2 Organization. (a) The Grain Inspection, Packers and Stockyards Administration (Packers and Stockyards Programs... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Organization. 204.2 Section 204.2...

9 CFR 204.5 - Indexes.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Indexes. 204.5 Section 204.5 Animals and Animal Products GRAIN INSPECTION, PACKERS AND STOCKYARDS ADMINISTRATION (PACKERS AND STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE ORGANIZATION AND FUNCTIONS Public Information § 204.5 Indexes...

9 CFR 204.2 - Organization.

Code of Federal Regulations, 2014 CFR

2014-01-01

... STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE ORGANIZATION AND FUNCTIONS Public Information § 204.2 Organization. (a) The Grain Inspection, Packers and Stockyards Administration (Packers and Stockyards Programs... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Organization. 204.2 Section 204.2...

9 CFR 204.5 - Indexes.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Indexes. 204.5 Section 204.5 Animals and Animal Products GRAIN INSPECTION, PACKERS AND STOCKYARDS ADMINISTRATION (PACKERS AND STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE ORGANIZATION AND FUNCTIONS Public Information § 204.5 Indexes...

9 CFR 204.7 - Appeals.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Appeals. 204.7 Section 204.7 Animals and Animal Products GRAIN INSPECTION, PACKERS AND STOCKYARDS ADMINISTRATION (PACKERS AND STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE ORGANIZATION AND FUNCTIONS Public Information § 204.7 Appeals. Any...

40 CFR 240.204 - Water quality.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Water quality. 240.204 Section 240.204 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.204 Water quality. ...

40 CFR 240.204 - Water quality.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Water quality. 240.204 Section 240.204 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.204 Water quality. ...

5 CFR 2638.204 - Deputy ethics official.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Deputy ethics official. 2638.204 Section 2638.204 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Designated Agency Ethics Official § 2638.204...

30 CFR 20.4 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false [Reserved] 20.4 Section 20.4 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MINE LAMPS OTHER THAN STANDARD CAP LAMPS § 20.4 [Reserved] ...

48 CFR 1517.204 - Contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contracts. 1517.204 Section 1517.204 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Options 1517.204 Contracts. The SCM may approve a contract with...

48 CFR 243.204 - Administration.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Administration. 243.204... OF DEFENSE CONTRACT MANAGEMENT CONTRACT MODIFICATIONS Change Orders 243.204 Administration. Follow the procedures at PGI 243.204 for administration of change orders. [75 FR 48277, Aug. 10, 2010] ...

30 CFR 20.4 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false [Reserved] 20.4 Section 20.4 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MINE LAMPS OTHER THAN STANDARD CAP LAMPS § 20.4 [Reserved] ...

30 CFR 20.4 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 1 2012-07-01 2012-07-01 false [Reserved] 20.4 Section 20.4 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MINE LAMPS OTHER THAN STANDARD CAP LAMPS § 20.4 [Reserved] ...

30 CFR 20.4 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false [Reserved] 20.4 Section 20.4 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MINE LAMPS OTHER THAN STANDARD CAP LAMPS § 20.4 [Reserved] ...

30 CFR 20.4 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 1 2013-07-01 2013-07-01 false [Reserved] 20.4 Section 20.4 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MINE LAMPS OTHER THAN STANDARD CAP LAMPS § 20.4 [Reserved] ...

41 CFR 101-6.204 - Discrimination prohibited.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Discrimination prohibited. 101-6.204 Section 101-6.204 Public Contracts and Property Management Federal Property Management...-Nondiscrimination in Programs Receiving Federal Financial Assistance § 101-6.204 Discrimination prohibited. ...

41 CFR 101-6.204 - Discrimination prohibited.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 41 Public Contracts and Property Management 2 2013-07-01 2012-07-01 true Discrimination prohibited. 101-6.204 Section 101-6.204 Public Contracts and Property Management Federal Property Management...-Nondiscrimination in Programs Receiving Federal Financial Assistance § 101-6.204 Discrimination prohibited. ...

41 CFR 101-6.204 - Discrimination prohibited.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 41 Public Contracts and Property Management 2 2011-07-01 2007-07-01 true Discrimination prohibited. 101-6.204 Section 101-6.204 Public Contracts and Property Management Federal Property Management...-Nondiscrimination in Programs Receiving Federal Financial Assistance § 101-6.204 Discrimination prohibited. ...

41 CFR 101-6.204 - Discrimination prohibited.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 41 Public Contracts and Property Management 2 2014-07-01 2012-07-01 true Discrimination prohibited. 101-6.204 Section 101-6.204 Public Contracts and Property Management Federal Property Management...-Nondiscrimination in Programs Receiving Federal Financial Assistance § 101-6.204 Discrimination prohibited. ...

41 CFR 101-6.204 - Discrimination prohibited.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 41 Public Contracts and Property Management 2 2012-07-01 2012-07-01 false Discrimination prohibited. 101-6.204 Section 101-6.204 Public Contracts and Property Management Federal Property Management...-Nondiscrimination in Programs Receiving Federal Financial Assistance § 101-6.204 Discrimination prohibited. ...

5 CFR 2638.204 - Deputy ethics official.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Deputy ethics official. 2638.204 Section 2638.204 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Designated Agency Ethics Official § 2638.204...

8 CFR 204.305 - State preadoption requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false State preadoption requirements. 204.305 Section 204.305 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRANT PETITIONS Intercountry Adoption of a Convention Adoptee § 204.305 State preadoption requirements. State...

31 CFR 587.204 - Evasions; attempts; conspiracies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Evasions; attempts; conspiracies. 587.204 Section 587.204 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... MONTENEGRO) MILOSEVIC SANCTIONS REGULATIONS Prohibitions § 587.204 Evasions; attempts; conspiracies. (a...

40 CFR 240.204 - Water quality.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Water quality. 240.204 Section 240.204 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.204 Water quality. ...

40 CFR 240.204 - Water quality.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Water quality. 240.204 Section 240.204 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.204 Water quality. ...

40 CFR 240.204 - Water quality.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Water quality. 240.204 Section 240.204 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.204 Water quality. ...

48 CFR 243.204 - Administration.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Administration. 243.204... OF DEFENSE CONTRACT MANAGEMENT CONTRACT MODIFICATIONS Change Orders 243.204 Administration. Follow the procedures at PGI 243.204 for administration of change orders. [75 FR 48277, Aug. 10, 2010] ...

48 CFR 243.204 - Administration.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Administration. 243.204... OF DEFENSE CONTRACT MANAGEMENT CONTRACT MODIFICATIONS Change Orders 243.204 Administration. Follow the procedures at PGI 243.204 for administration of change orders. [75 FR 48277, Aug. 10, 2010] ...

48 CFR 243.204 - Administration.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Administration. 243.204... OF DEFENSE CONTRACT MANAGEMENT CONTRACT MODIFICATIONS Change Orders 243.204 Administration. Follow the procedures at PGI 243.204 for administration of change orders. [75 FR 48277, Aug. 10, 2010] ...

48 CFR 6.204 - Section 8(a) competition.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Section 8(a) competition. 6.204 Section 6.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION ACQUISITION PLANNING COMPETITION REQUIREMENTS Full and Open Competition After Exclusion of Sources 6.204...

20 CFR 725.204 - Determination of relationship; spouse.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Determination of relationship; spouse. 725.204 Section 725.204 Employees' Benefits EMPLOYMENT STANDARDS ADMINISTRATION, DEPARTMENT OF LABOR...) § 725.204 Determination of relationship; spouse. (a) For the purpose of augmenting benefits, an...

5 CFR 2638.204 - Deputy ethics official.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 3 2012-01-01 2012-01-01 false Deputy ethics official. 2638.204 Section 2638.204 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Designated Agency Ethics Official § 2638.204...

5 CFR 2638.204 - Deputy ethics official.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false Deputy ethics official. 2638.204 Section 2638.204 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Designated Agency Ethics Official § 2638.204...

5 CFR 2638.204 - Deputy ethics official.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 3 2014-01-01 2014-01-01 false Deputy ethics official. 2638.204 Section 2638.204 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Designated Agency Ethics Official § 2638.204...

42 CFR 66.204 - Application.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Application. 66.204 Section 66.204 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL RESEARCH SERVICE AWARDS Institutional Grants § 66.204 Application. (a) Application for a grant...

42 CFR 66.204 - Application.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Application. 66.204 Section 66.204 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL RESEARCH SERVICE AWARDS Institutional Grants § 66.204 Application. (a) Application for a grant...

42 CFR 66.204 - Application.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Application. 66.204 Section 66.204 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL RESEARCH SERVICE AWARDS Institutional Grants § 66.204 Application. (a) Application for a grant...

48 CFR 243.204 - Administration.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Administration. 243.204... OF DEFENSE CONTRACT MANAGEMENT CONTRACT MODIFICATIONS Change Orders 243.204 Administration. Follow the procedures at PGI 243.204 for administration of change orders. [75 FR 48277, Aug. 10, 2010] ...

Radiogenic Isotopes As Paleoceanographic Tracers in Deep-Sea Corals: Advances in TIMS Measurements of Pb Isotopes and Application to Southern Ocean Corals

NASA Astrophysics Data System (ADS)

Wilson, D. J.; van de Flierdt, T.; Bridgestock, L. J.; Paul, M.; Rehkamper, M.; Robinson, L. F.; Adkins, J. F.

2014-12-01

Deep-sea corals have emerged as a valuable archive of deep ocean paleoceanographic change, with uranium-series dating providing absolute ages and the potential for centennial resolution. In combination with measurements of radiocarbon, neodymium isotopes and clumped isotopes, this archive has recently been exploited to reconstruct changes in ventilation, water mass sourcing and temperature in relation to millennial climate change. Lead (Pb) isotopes in both corals and seawater have also been used to track anthropogenic inputs through space and time and to trace transport pathways within the oceans. Better understanding of the oceanic Pb cycle is emerging from the GEOTRACES programme. However, while Pb isotopes have been widely used in environmental studies, their full potential as a (pre-anthropogenic) paleoceanographic tracer remains to be exploited. In deep-sea corals, challenges exist from low Pb concentrations in aragonite in comparison to secondary coatings, the potential for contamination, and the efficient elemental separation required for measurement by thermal ionisation mass spectrometry (TIMS). Here we discuss progress in measuring Pb isotopes in coral aragonite using a 207Pb-204Pb double spike on a ThermoFinnigan Triton TIMS. For a 2 ng NIST-981 Pb standard, the long term reproducibility (using 1011 Ω resistors) is ~1000 ppm (2 s.d.) on 206Pb/204Pb, 207Pb/204Pb and 208Pb/204Pb ratios. We now show that using a new 1012 Ω resistor to measure the small 204Pb beam improves the internal precision on these ratios from ~500 ppm (2 s.e.) to ~250 ppm (2 s.e.) and we envisage a potential improvement in the long term reproducibility as a consequence. We further assess the internal precision and external reproducibility of our method using a BCR-2 rock standard and an in-house coral standard. Preliminary evidence on the application of this method to natural samples is derived from cleaning experiments and replication tests on deep-sea corals from the Southern Ocean.

32 CFR 204.4 - Responsibilities.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false Responsibilities. 204.4 Section 204.4 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS USER FEES § 204.4 Responsibilities. (a) The USD(C) shall develop and monitor policies governing user...

47 CFR 0.204 - The exercise of delegated authority.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 47 Telecommunication 1 2012-10-01 2012-10-01 false The exercise of delegated authority. 0.204 Section 0.204 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION Delegations of Authority General § 0.204 The exercise of delegated authority. (a) Authority to issue orders...

47 CFR 0.204 - The exercise of delegated authority.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 1 2013-10-01 2013-10-01 false The exercise of delegated authority. 0.204 Section 0.204 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION Delegations of Authority General § 0.204 The exercise of delegated authority. (a) Authority to issue orders...

47 CFR 0.204 - The exercise of delegated authority.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 1 2011-10-01 2011-10-01 false The exercise of delegated authority. 0.204 Section 0.204 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION Delegations of Authority General § 0.204 The exercise of delegated authority. (a) Authority to issue orders...

47 CFR 0.204 - The exercise of delegated authority.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 1 2014-10-01 2014-10-01 false The exercise of delegated authority. 0.204 Section 0.204 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION Delegations of Authority General § 0.204 The exercise of delegated authority. (a) Authority to issue orders...

48 CFR 204.101 - Contracting officer's signature.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contracting officer's signature. 204.101 Section 204.101 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS... officer's signature. Follow the procedures at PGI 204.101 for signature of contract documents. [71 FR 9268...

31 CFR 598.204 - Evasions; attempts; conspiracies.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Evasions; attempts; conspiracies. 598.204 Section 598.204 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... REGULATIONS Prohibitions § 598.204 Evasions; attempts; conspiracies. Except to the extent provided in...

31 CFR 598.204 - Evasions; attempts; conspiracies.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Evasions; attempts; conspiracies. 598.204 Section 598.204 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... REGULATIONS Prohibitions § 598.204 Evasions; attempts; conspiracies. Except to the extent provided in...

31 CFR 598.204 - Evasions; attempts; conspiracies.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Evasions; attempts; conspiracies. 598.204 Section 598.204 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... REGULATIONS Prohibitions § 598.204 Evasions; attempts; conspiracies. Except to the extent provided in...

31 CFR 598.204 - Evasions; attempts; conspiracies.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Evasions; attempts; conspiracies. 598.204 Section 598.204 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... REGULATIONS Prohibitions § 598.204 Evasions; attempts; conspiracies. Except to the extent provided in...

40 CFR 240.204-1 - Requirement.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirement. 240.204-1 Section 240.204-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.204-1 Requirement...

40 CFR 240.204-1 - Requirement.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirement. 240.204-1 Section 240.204-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.204-1 Requirement...

40 CFR 240.204-1 - Requirement.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirement. 240.204-1 Section 240.204-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.204-1 Requirement...

47 CFR 0.204 - The exercise of delegated authority.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false The exercise of delegated authority. 0.204 Section 0.204 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION Delegations of Authority General § 0.204 The exercise of delegated authority. (a) Authority to issue orders...

44 CFR 204.21 - Fire management assistance declaration criteria.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Declaration Process § 204.21 Fire management assistance declaration criteria. (a) Determinations. We will... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Fire management assistance declaration criteria. 204.21 Section 204.21 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT...

44 CFR 204.21 - Fire management assistance declaration criteria.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Declaration Process § 204.21 Fire management assistance declaration criteria. (a) Determinations. We will... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Fire management assistance declaration criteria. 204.21 Section 204.21 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT...

44 CFR 204.21 - Fire management assistance declaration criteria.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Declaration Process § 204.21 Fire management assistance declaration criteria. (a) Determinations. We will... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Fire management assistance declaration criteria. 204.21 Section 204.21 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT...

44 CFR 204.21 - Fire management assistance declaration criteria.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Declaration Process § 204.21 Fire management assistance declaration criteria. (a) Determinations. We will... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Fire management assistance declaration criteria. 204.21 Section 204.21 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT...

44 CFR 204.21 - Fire management assistance declaration criteria.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Declaration Process § 204.21 Fire management assistance declaration criteria. (a) Determinations. We will... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Fire management assistance declaration criteria. 204.21 Section 204.21 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT...

29 CFR 1614.204 - Class complaints.

Code of Federal Regulations, 2011 CFR

2011-07-01

... media employed to give notice of the existence of the class complaint. The notice, where appropriate... 29 Labor 4 2011-07-01 2011-07-01 false Class complaints. 1614.204 Section 1614.204 Labor... EMPLOYMENT OPPORTUNITY Provisions Applicable to Particular Complaints § 1614.204 Class complaints. (a...

5 CFR 362.204 - Conversion to the competitive service.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Conversion to the competitive service. 362.204 Section 362.204 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PATHWAYS PROGRAMS Internship Program § 362.204 Conversion to the competitive service. (a) An...

5 CFR 362.204 - Conversion to the competitive service.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Conversion to the competitive service. 362.204 Section 362.204 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PATHWAYS PROGRAMS Internship Program § 362.204 Conversion to the competitive service. (a) An...

20 CFR 725.204 - Determination of relationship; spouse.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Determination of relationship; spouse. 725.204 Section 725.204 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR...) § 725.204 Determination of relationship; spouse. (a) For the purpose of augmenting benefits, an...

7 CFR 1430.204 - Requesting benefits.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 10 2014-01-01 2014-01-01 false Requesting benefits. 1430.204 Section 1430.204... Program § 1430.204 Requesting benefits. (a) A request for benefits or contract application, under this... MILC benefits must certify the accuracy and truthfulness of the information in their contract...

7 CFR 1430.204 - Requesting benefits.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 10 2013-01-01 2013-01-01 false Requesting benefits. 1430.204 Section 1430.204... Program § 1430.204 Requesting benefits. (a) A request for benefits or contract application, under this... MILC benefits must certify the accuracy and truthfulness of the information in their contract...

7 CFR 1430.204 - Requesting benefits.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Requesting benefits. 1430.204 Section 1430.204... Program § 1430.204 Requesting benefits. (a) A request for benefits or contract application, under this... MILC benefits must certify the accuracy and truthfulness of the information in their contract...

7 CFR 1430.204 - Requesting benefits.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 10 2012-01-01 2012-01-01 false Requesting benefits. 1430.204 Section 1430.204... Program § 1430.204 Requesting benefits. (a) A request for benefits or contract application, under this... MILC benefits must certify the accuracy and truthfulness of the information in their contract...

7 CFR 1430.204 - Requesting benefits.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Requesting benefits. 1430.204 Section 1430.204... Program § 1430.204 Requesting benefits. (a) A request for benefits or contract application, under this... MILC benefits must certify the accuracy and truthfulness of the information in their contract...

8 CFR 204.301 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Definitions. 204.301 Section 204.301 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRANT PETITIONS Intercountry Adoption of a Convention Adoptee § 204.301 Definitions. The definitions in 22 CFR 96.2 apply to...

8 CFR 204.303 - Determination of habitual residence.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Determination of habitual residence. 204.303 Section 204.303 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRANT PETITIONS Intercountry Adoption of a Convention Adoptee § 204.303 Determination of habitual...

40 CFR 240.204-1 - Requirement.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Requirement. 240.204-1 Section 240.204-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.204-1 Requirement...

31 CFR 541.204 - Evasions; attempts; conspiracies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Evasions; attempts; conspiracies. 541.204 Section 541.204 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... § 541.204 Evasions; attempts; conspiracies. (a) Except as otherwise authorized, and notwithstanding any...

31 CFR 598.204 - Evasions; attempts; conspiracies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Evasions; attempts; conspiracies. 598.204 Section 598.204 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... REGULATIONS Prohibitions § 598.204 Evasions; attempts; conspiracies. Except to the extent provided in...

31 CFR 588.204 - Evasions; attempts; conspiracies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Evasions; attempts; conspiracies. 588.204 Section 588.204 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... Prohibitions § 588.204 Evasions; attempts; conspiracies. (a) Except as otherwise authorized, and...

1 CFR 20.4 - Description of program activities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 1 General Provisions 1 2010-01-01 2010-01-01 false Description of program activities. 20.4 Section 20.4 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER PREPARATION, TRANSMITTAL, AND PROCESSING OF DOCUMENTS HANDLING OF THE UNITED STATES GOVERNMENT MANUAL STATEMENTS § 20.4...

48 CFR 204.805 - Disposal of contract files.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Disposal of contract files. 204.805 Section 204.805 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.805 Disposal of contract files. (1...

48 CFR 204.804 - Closeout of contract files.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Closeout of contract files. 204.804 Section 204.804 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.804 Closeout of contract files. (1...

48 CFR 204.804 - Closeout of contract files.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Closeout of contract files. 204.804 Section 204.804 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.804 Closeout of contract files...

48 CFR 204.805 - Disposal of contract files.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Disposal of contract files. 204.805 Section 204.805 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.805 Disposal of contract files. (1...

48 CFR 204.805 - Disposal of contract files.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Disposal of contract files. 204.805 Section 204.805 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.805 Disposal of contract files. (1...

48 CFR 204.805 - Disposal of contract files.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Disposal of contract files. 204.805 Section 204.805 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.805 Disposal of contract files. (1...

48 CFR 204.804 - Closeout of contract files.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Closeout of contract files. 204.804 Section 204.804 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.804 Closeout of contract files...

48 CFR 204.804 - Closeout of contract files.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Closeout of contract files. 204.804 Section 204.804 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.804 Closeout of contract files. (1...

48 CFR 204.805 - Disposal of contract files.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Disposal of contract files. 204.805 Section 204.805 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.805 Disposal of contract files. (1...

48 CFR 204.804 - Closeout of contract files.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Closeout of contract files. 204.804 Section 204.804 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.804 Closeout of contract files. (1...

18 CFR 706.204 - Financial interests.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Financial interests. 706.204 Section 706.204 Conservation of Power and Water Resources WATER RESOURCES COUNCIL EMPLOYEE RESPONSIBILITIES AND CONDUCT Conduct and Responsibilities of Employees § 706.204 Financial interests. (a) An...

18 CFR 706.204 - Financial interests.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Financial interests. 706.204 Section 706.204 Conservation of Power and Water Resources WATER RESOURCES COUNCIL EMPLOYEE RESPONSIBILITIES AND CONDUCT Conduct and Responsibilities of Employees § 706.204 Financial interests. (a) An...

18 CFR 706.204 - Financial interests.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 2 2014-04-01 2014-04-01 false Financial interests. 706.204 Section 706.204 Conservation of Power and Water Resources WATER RESOURCES COUNCIL EMPLOYEE RESPONSIBILITIES AND CONDUCT Conduct and Responsibilities of Employees § 706.204 Financial interests. (a) An...

18 CFR 706.204 - Financial interests.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 2 2012-04-01 2012-04-01 false Financial interests. 706.204 Section 706.204 Conservation of Power and Water Resources WATER RESOURCES COUNCIL EMPLOYEE RESPONSIBILITIES AND CONDUCT Conduct and Responsibilities of Employees § 706.204 Financial interests. (a) An...

18 CFR 706.204 - Financial interests.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 2 2013-04-01 2012-04-01 true Financial interests. 706.204 Section 706.204 Conservation of Power and Water Resources WATER RESOURCES COUNCIL EMPLOYEE RESPONSIBILITIES AND CONDUCT Conduct and Responsibilities of Employees § 706.204 Financial interests. (a) An...

28 CFR 16.204 - Public notice.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Public notice. 16.204 Section 16.204 Judicial Administration DEPARTMENT OF JUSTICE PRODUCTION OR DISCLOSURE OF MATERIAL OR INFORMATION Public Observation of Parole Commission Meetings § 16.204 Public notice. (a) Requirements. Every open meeting and...

44 CFR 204.2 - Scope.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Scope. 204.2 Section 204.2 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FIRE MANAGEMENT ASSISTANCE GRANT PROGRAM General § 204.2 Scope. This part is intended...

44 CFR 204.2 - Scope.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Scope. 204.2 Section 204.2 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FIRE MANAGEMENT ASSISTANCE GRANT PROGRAM General § 204.2 Scope. This part is intended...

44 CFR 204.2 - Scope.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Scope. 204.2 Section 204.2 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FIRE MANAGEMENT ASSISTANCE GRANT PROGRAM General § 204.2 Scope. This part is intended...

44 CFR 204.2 - Scope.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Scope. 204.2 Section 204.2 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FIRE MANAGEMENT ASSISTANCE GRANT PROGRAM General § 204.2 Scope. This part is intended...

31 CFR 586.204 - Prohibited new investment within Serbia.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Serbia. 586.204 Section 586.204 Money and Finance: Treasury Regulations Relating to Money and Finance... (SERBIA & MONTENEGRO) KOSOVO SANCTIONS REGULATIONS Prohibitions § 586.204 Prohibited new investment within Serbia. Except as otherwise provided in regulations, orders, directives, or licenses that may hereafter...

In vitro and in vivo evaluation of osteoinductivity and bone fusion ability of an activin a/BMP2 chimera (AB204): a comparison study between AB204 and rhBMP-2.

PubMed

Zheng, Guang Bin; Lee, Jae Hyup; Jin, Yuan-Zhe

2017-12-01

This study compared osteoinductivity and osteogenic capacity between AB204 and rhBMP-2 using hMSCs in vitro and a beagle's posterolateral spinal fusion model. Cultured hMSCs were treated with AB204 or rhBMP-2 with low to high doses. Three male beagles were performed posterolateral spinal fusion with biphasic calcium phosphate (2 ml) + AB204 or rhBMP-2 (20, 50 or 200 µg). They were euthanized after 8 weeks. The fusion rate and bone formation of spine samples were examined. AB204 had higher alkaline phosphatase activity, mineralization and osteogenic-related gene expression than rhBMP-2. Fusion rates in all rhBMP-2 groups were 0. They were 100% for 50 μg and 200 μg AB204 groups. Therefore, AB204 showed higher osteogenicity than rhBMP-2. It could be a better bone graft substitute.

32 CFR 204.6 - Collections.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false Collections. 204.6 Section 204.6 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS USER FEES § 204.6 Collections. (a) Collections of fees will be made in advance or simultaneously with...

17 CFR 204.64 - Hearing.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false Hearing. 204.64 Section 204.64... Administrative Wage Garnishment § 204.64 Hearing. (a) Request for hearing. The Commission will order a hearing... hearing concerning, for debts not previously established by judicial or administrative order, the...

17 CFR 204.56 - Administrative charges.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false Administrative charges. 204.56 Section 204.56 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION RULES RELATING TO DEBT COLLECTION Tax Refund Offset § 204.56 Administrative charges. To the extent permitted by law, all...

17 CFR 204.56 - Administrative charges.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Administrative charges. 204.56 Section 204.56 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION RULES RELATING TO DEBT COLLECTION Tax Refund Offset § 204.56 Administrative charges. To the extent permitted by law, all...

40 CFR 243.204-1 - Requirement.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirement. 243.204-1 Section 243.204... THE STORAGE AND COLLECTION OF RESIDENTIAL, COMMERCIAL, AND INSTITUTIONAL SOLID WASTE Requirements and Recommended Procedures § 243.204-1 Requirement. The collection of solid wastes (or materials which have been...

40 CFR 243.204-1 - Requirement.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirement. 243.204-1 Section 243.204... THE STORAGE AND COLLECTION OF RESIDENTIAL, COMMERCIAL, AND INSTITUTIONAL SOLID WASTE Requirements and Recommended Procedures § 243.204-1 Requirement. The collection of solid wastes (or materials which have been...

40 CFR 243.204-1 - Requirement.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirement. 243.204-1 Section 243.204... THE STORAGE AND COLLECTION OF RESIDENTIAL, COMMERCIAL, AND INSTITUTIONAL SOLID WASTE Requirements and Recommended Procedures § 243.204-1 Requirement. The collection of solid wastes (or materials which have been...

6 CFR 27.204 - Minimum concentration by security issue.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 6 Domestic Security 1 2010-01-01 2010-01-01 false Minimum concentration by security issue. 27.204 Section 27.204 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Chemical Facility Security Program § 27.204 Minimum concentration by...

40 CFR 204.52 - Portable air compressor noise emission standard.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Portable air compressor noise emission standard. 204.52 Section 204.52 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS NOISE EMISSION STANDARDS FOR CONSTRUCTION EQUIPMENT Portable Air Compressors § 204.52...

19 CFR 201.204 - Salary offset.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 3 2010-04-01 2010-04-01 false Salary offset. 201.204 Section 201.204 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF GENERAL APPLICATION Debt Collection § 201.204 Salary offset. (a) Notice requirements before offset where the Commission is the creditor...

19 CFR 201.204 - Salary offset.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 3 2013-04-01 2013-04-01 false Salary offset. 201.204 Section 201.204 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF GENERAL APPLICATION Debt Collection § 201.204 Salary offset. (a) Notice requirements before offset where the Commission is the creditor...

19 CFR 201.204 - Salary offset.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 3 2011-04-01 2011-04-01 false Salary offset. 201.204 Section 201.204 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF GENERAL APPLICATION Debt Collection § 201.204 Salary offset. (a) Notice requirements before offset where the Commission is the creditor...

19 CFR 201.204 - Salary offset.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 3 2012-04-01 2012-04-01 false Salary offset. 201.204 Section 201.204 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF GENERAL APPLICATION Debt Collection § 201.204 Salary offset. (a) Notice requirements before offset where the Commission is the creditor...

44 CFR 204.3 - Definitions used throughout this part.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Definitions used throughout this part. 204.3 Section 204.3 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FIRE MANAGEMENT ASSISTANCE GRANT PROGRAM General § 204.3...

44 CFR 204.3 - Definitions used throughout this part.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Definitions used throughout this part. 204.3 Section 204.3 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FIRE MANAGEMENT ASSISTANCE GRANT PROGRAM General § 204.3...

8 CFR 204.6 - Petitions for employment creation aliens.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Petitions for employment creation aliens. 204.6 Section 204.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRANT PETITIONS Immigrant Visa Petitions § 204.6 Petitions for employment creation aliens. (a) General...

8 CFR 204.6 - Petitions for employment creation aliens.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Petitions for employment creation aliens. 204.6 Section 204.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRANT PETITIONS Immigrant Visa Petitions § 204.6 Petitions for employment creation aliens. (a) General...

8 CFR 204.6 - Petitions for employment creation aliens.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Petitions for employment creation aliens. 204.6 Section 204.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRANT PETITIONS Immigrant Visa Petitions § 204.6 Petitions for employment creation aliens. (a) General...

8 CFR 204.6 - Petitions for employment creation aliens.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Petitions for employment creation aliens. 204.6 Section 204.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRANT PETITIONS Immigrant Visa Petitions § 204.6 Petitions for employment creation aliens. (a) General...

48 CFR 243.204-70-4 - Limitations on obligations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Limitations on obligations. 243.204-70-4 Section 243.204-70-4 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT CONTRACT MODIFICATIONS Change Orders 243.204-70...

47 CFR 73.204 - International agreements and other restrictions on use of channels.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 4 2010-10-01 2010-10-01 false International agreements and other restrictions on use of channels. 73.204 Section 73.204 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES RADIO BROADCAST SERVICES FM Broadcast Stations § 73.204 International...

47 CFR 73.204 - International agreements and other restrictions on use of channels.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 4 2011-10-01 2011-10-01 false International agreements and other restrictions on use of channels. 73.204 Section 73.204 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES RADIO BROADCAST SERVICES FM Broadcast Stations § 73.204 International...

40 CFR 204.52 - Portable air compressor noise emission standard.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Portable air compressor noise emission standard. 204.52 Section 204.52 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS NOISE EMISSION STANDARDS FOR CONSTRUCTION EQUIPMENT Portable Air Compressors § 204.52...

37 CFR 204.9 - Judicial review.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Judicial review. 204.9 Section 204.9 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT OFFICE AND PROCEDURES PRIVACY ACT: POLICIES AND PROCEDURES § 204.9 Judicial review. Within two years of the...

37 CFR 204.6 - Fees.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Fees. 204.6 Section 204.6 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT OFFICE AND PROCEDURES PRIVACY ACT: POLICIES AND PROCEDURES § 204.6 Fees. (a) The Copyright Office will provide, free of charge...

37 CFR 204.2 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Definitions. 204.2 Section 204.2 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT OFFICE AND PROCEDURES PRIVACY ACT: POLICIES AND PROCEDURES § 204.2 Definitions. For purposes of this part: (a) The term...

8 CFR 204.314 - Appeal.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Appeal. 204.314 Section 204.314 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRANT PETITIONS Intercountry Adoption of a Convention Adoptee § 204.314 Appeal. (a) Decisions that may be appealed. (1) Except as provided...

48 CFR 428.204 - Alternatives in lieu of corporate or individual sureties.

Code of Federal Regulations, 2010 CFR

2010-10-01

... corporate or individual sureties. 428.204 Section 428.204 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Sureties and Other Security for Bonds 428.204 Alternatives in lieu of corporate or individual sureties. HCA's shall establish procedures...

48 CFR 428.204 - Alternatives in lieu of corporate or individual sureties.

Code of Federal Regulations, 2012 CFR

2012-10-01

... corporate or individual sureties. 428.204 Section 428.204 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Sureties and Other Security for Bonds 428.204 Alternatives in lieu of corporate or individual sureties. HCA's shall establish procedures...

48 CFR 428.204 - Alternatives in lieu of corporate or individual sureties.

Code of Federal Regulations, 2013 CFR

2013-10-01

... corporate or individual sureties. 428.204 Section 428.204 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Sureties and Other Security for Bonds 428.204 Alternatives in lieu of corporate or individual sureties. HCA's shall establish procedures...

48 CFR 428.204 - Alternatives in lieu of corporate or individual sureties.

Code of Federal Regulations, 2014 CFR

2014-10-01

... corporate or individual sureties. 428.204 Section 428.204 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Sureties and Other Security for Bonds 428.204 Alternatives in lieu of corporate or individual sureties. HCA's shall establish procedures...

48 CFR 428.204 - Alternatives in lieu of corporate or individual sureties.

Code of Federal Regulations, 2011 CFR

2011-10-01

... corporate or individual sureties. 428.204 Section 428.204 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Sureties and Other Security for Bonds 428.204 Alternatives in lieu of corporate or individual sureties. HCA's shall establish procedures...

5 CFR 930.204 - Appointments and conditions of employment.

Code of Federal Regulations, 2013 CFR

2013-01-01

.... 930.204 Section 930.204 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL...) Administrative Law Judge Program § 930.204 Appointments and conditions of employment. (a) Appointment. An agency may appoint an individual to an administrative law judge position only with prior approval of OPM...

5 CFR 930.204 - Appointments and conditions of employment.

Code of Federal Regulations, 2012 CFR

2012-01-01

.... 930.204 Section 930.204 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL...) Administrative Law Judge Program § 930.204 Appointments and conditions of employment. (a) Appointment. An agency may appoint an individual to an administrative law judge position only with prior approval of OPM...

7 CFR 59.204 - Mandatory weekly reporting for swine.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 3 2012-01-01 2012-01-01 false Mandatory weekly reporting for swine. 59.204 Section 59.204 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... (CONTINUED) LIVESTOCK MANDATORY REPORTING Swine Reporting § 59.204 Mandatory weekly reporting for swine. (a...

7 CFR 59.204 - Mandatory weekly reporting for swine.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 3 2011-01-01 2011-01-01 false Mandatory weekly reporting for swine. 59.204 Section 59.204 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... (CONTINUED) LIVESTOCK MANDATORY REPORTING Swine Reporting § 59.204 Mandatory weekly reporting for swine. (a...

7 CFR 59.204 - Mandatory weekly reporting for swine.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 3 2014-01-01 2014-01-01 false Mandatory weekly reporting for swine. 59.204 Section 59.204 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... (CONTINUED) LIVESTOCK MANDATORY REPORTING Swine Reporting § 59.204 Mandatory weekly reporting for swine. (a...

7 CFR 59.204 - Mandatory weekly reporting for swine.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 3 2013-01-01 2013-01-01 false Mandatory weekly reporting for swine. 59.204 Section 59.204 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... (CONTINUED) LIVESTOCK MANDATORY REPORTING Swine Reporting § 59.204 Mandatory weekly reporting for swine. (a...

7 CFR 59.204 - Mandatory weekly reporting for swine.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Mandatory weekly reporting for swine. 59.204 Section 59.204 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... (CONTINUED) LIVESTOCK MANDATORY REPORTING Swine Reporting § 59.204 Mandatory weekly reporting for swine. (a...

45 CFR 160.204 - Process for requesting exception determinations.

Code of Federal Regulations, 2010 CFR

2010-10-01

.... 160.204 Section 160.204 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES ADMINISTRATIVE DATA STANDARDS AND RELATED REQUIREMENTS GENERAL ADMINISTRATIVE REQUIREMENTS Preemption of State Law § 160.204 Process for requesting exception determinations. (a) A request to except a provision of State law from...

5 CFR 841.204 - Deemed application to protect survivors.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Deemed application to protect survivors. 841.204 Section 841.204 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL... for Benefits § 841.204 Deemed application to protect survivors. (a) A former employee is deemed to...

5 CFR 841.204 - Deemed application to protect survivors.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Deemed application to protect survivors. 841.204 Section 841.204 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL... for Benefits § 841.204 Deemed application to protect survivors. (a) A former employee is deemed to...

5 CFR 841.204 - Deemed application to protect survivors.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Deemed application to protect survivors. 841.204 Section 841.204 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL... for Benefits § 841.204 Deemed application to protect survivors. (a) A former employee is deemed to...

5 CFR 841.204 - Deemed application to protect survivors.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Deemed application to protect survivors. 841.204 Section 841.204 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL... for Benefits § 841.204 Deemed application to protect survivors. (a) A former employee is deemed to...

5 CFR 841.204 - Deemed application to protect survivors.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Deemed application to protect survivors. 841.204 Section 841.204 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL... for Benefits § 841.204 Deemed application to protect survivors. (a) A former employee is deemed to...

48 CFR 243.204-70-4 - Limitations on obligations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Limitations on obligations. 243.204-70-4 Section 243.204-70-4 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT CONTRACT MODIFICATIONS Change Orders 243.204-70...

37 CFR 41.204 - Notice of basis for relief.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Notice of basis for relief. 41.204 Section 41.204 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE PRACTICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Patent Interferences § 41.204 Notice...

12 CFR 204.121 - Bankers' banks.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 2 2011-01-01 2011-01-01 false Bankers' banks. 204.121 Section 204.121 Banks... REQUIREMENTS OF DEPOSITORY INSTITUTIONS (REGULATION D) Interpretations § 204.121 Bankers' banks. (a)(1) The...' banks. (2) In its application of these requirements to specific institutions, the Board will use the...

32 CFR 204.1 - Purpose.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false Purpose. 204.1 Section 204.1 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS USER FEES § 204.1 Purpose. This part implements the DoD program under Title 31, United States Code, section 9701...

48 CFR 204.470 - U.S.-International Atomic Energy Agency Additional Protocol.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false U.S.-International Atomic Energy Agency Additional Protocol. 204.470 Section 204.470 Federal Acquisition Regulations System DEFENSE... Information Within Industry 204.470 U.S.-International Atomic Energy Agency Additional Protocol. ...

48 CFR 204.470 - U.S.-International Atomic Energy Agency Additional Protocol.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false U.S.-International Atomic Energy Agency Additional Protocol. 204.470 Section 204.470 Federal Acquisition Regulations System DEFENSE... Information Within Industry 204.470 U.S.-International Atomic Energy Agency Additional Protocol. ...

48 CFR 204.470 - U.S.-International Atomic Energy Agency Additional Protocol.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false U.S.-International Atomic Energy Agency Additional Protocol. 204.470 Section 204.470 Federal Acquisition Regulations System DEFENSE... Information Within Industry 204.470 U.S.-International Atomic Energy Agency Additional Protocol. ...

48 CFR 204.470 - U.S.-International Atomic Energy Agency Additional Protocol.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false U.S.-International Atomic Energy Agency Additional Protocol. 204.470 Section 204.470 Federal Acquisition Regulations System DEFENSE... Information Within Industry 204.470 U.S.-International Atomic Energy Agency Additional Protocol. ...

48 CFR 204.470 - U.S.-International Atomic Energy Agency Additional Protocol.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false U.S.-International Atomic Energy Agency Additional Protocol. 204.470 Section 204.470 Federal Acquisition Regulations System DEFENSE... Information Within Industry 204.470 U.S.-International Atomic Energy Agency Additional Protocol. ...

8 CFR 204.301 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Definitions. 204.301 Section 204.301 Aliens... 204.300(b), means the adoption, on or after the Convention effective date, of an alien child... disappeared if it is established that the stepparent either never knew of the child's existence, or never knew...

42 CFR 50.204 - Informed consent requirement.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Informed consent requirement. 50.204 Section 50.204 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS POLICIES OF GENERAL APPLICABILITY Sterilization of Persons in Federally Assisted Family Planning Projects § 50.204 Informed consent requirement. Informed consent...

42 CFR 50.204 - Informed consent requirement.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Informed consent requirement. 50.204 Section 50.204 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS POLICIES OF GENERAL APPLICABILITY Sterilization of Persons in Federally Assisted Family Planning Projects § 50.204 Informed consent requirement. Informed consent...

42 CFR 50.204 - Informed consent requirement.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Informed consent requirement. 50.204 Section 50.204 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS POLICIES OF GENERAL APPLICABILITY Sterilization of Persons in Federally Assisted Family Planning Projects § 50.204 Informed consent requirement. Informed consent...

42 CFR 50.204 - Informed consent requirement.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Informed consent requirement. 50.204 Section 50.204 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS POLICIES OF GENERAL APPLICABILITY Sterilization of Persons in Federally Assisted Family Planning Projects § 50.204 Informed consent requirement. Informed consent...

42 CFR 50.204 - Informed consent requirement.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Informed consent requirement. 50.204 Section 50.204 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS POLICIES OF GENERAL APPLICABILITY Sterilization of Persons in Federally Assisted Family Planning Projects § 50.204 Informed consent requirement. Informed consent...

28 CFR 5.204 - Amendments.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Amendments. 5.204 Section 5.204 Judicial Administration DEPARTMENT OF JUSTICE ADMINISTRATION AND ENFORCEMENT OF FOREIGN AGENTS REGISTRATION ACT OF 1938, AS AMENDED § 5.204 Amendments. (a) An initial, supplemental, or final statement which is deemed deficient by the Assistant Attorney...

28 CFR 5.204 - Amendments.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Amendments. 5.204 Section 5.204 Judicial Administration DEPARTMENT OF JUSTICE ADMINISTRATION AND ENFORCEMENT OF FOREIGN AGENTS REGISTRATION ACT OF 1938, AS AMENDED § 5.204 Amendments. (a) An initial, supplemental, or final statement which is deemed deficient by the Assistant Attorney...

28 CFR 5.204 - Amendments.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Amendments. 5.204 Section 5.204 Judicial Administration DEPARTMENT OF JUSTICE ADMINISTRATION AND ENFORCEMENT OF FOREIGN AGENTS REGISTRATION ACT OF 1938, AS AMENDED § 5.204 Amendments. (a) An initial, supplemental, or final statement which is deemed deficient by the Assistant Attorney...

28 CFR 5.204 - Amendments.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Amendments. 5.204 Section 5.204 Judicial Administration DEPARTMENT OF JUSTICE ADMINISTRATION AND ENFORCEMENT OF FOREIGN AGENTS REGISTRATION ACT OF 1938, AS AMENDED § 5.204 Amendments. (a) An initial, supplemental, or final statement which is deemed deficient by the Assistant Attorney...

28 CFR 5.204 - Amendments.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Amendments. 5.204 Section 5.204 Judicial Administration DEPARTMENT OF JUSTICE ADMINISTRATION AND ENFORCEMENT OF FOREIGN AGENTS REGISTRATION ACT OF 1938, AS AMENDED § 5.204 Amendments. (a) An initial, supplemental, or final statement which is deemed deficient by the Assistant Attorney...

10 CFR 835.204 - Planned special exposures.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Planned special exposures. 835.204 Section 835.204 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Standards for Internal and External Exposure § 835.204 Planned special exposures. (a) A planned special exposure may be authorized for a radiological worker to...

40 CFR 204.57-9 - Prohibition of distribution in commerce; manufacturer's -remedy.

Code of Federal Regulations, 2013 CFR

2013-07-01

... commerce; manufacturer's -remedy. 204.57-9 Section 204.57-9 Protection of Environment ENVIRONMENTAL... Portable Air Compressors § 204.57-9 Prohibition of distribution in commerce; manufacturer's -remedy. (a... noise emission tests conducted pursuant to this Subpart B may not be distributed in commerce until...

40 CFR 204.57-9 - Prohibition of distribution in commerce; manufacturer's -remedy.

Code of Federal Regulations, 2014 CFR

2014-07-01

... commerce; manufacturer's -remedy. 204.57-9 Section 204.57-9 Protection of Environment ENVIRONMENTAL... Portable Air Compressors § 204.57-9 Prohibition of distribution in commerce; manufacturer's -remedy. (a... noise emission tests conducted pursuant to this Subpart B may not be distributed in commerce until...

40 CFR 204.57-9 - Prohibition of distribution in commerce; manufacturer's -remedy.

Code of Federal Regulations, 2011 CFR

2011-07-01

... commerce; manufacturer's -remedy. 204.57-9 Section 204.57-9 Protection of Environment ENVIRONMENTAL... Portable Air Compressors § 204.57-9 Prohibition of distribution in commerce; manufacturer's -remedy. (a... noise emission tests conducted pursuant to this Subpart B may not be distributed in commerce until...

40 CFR 204.57-9 - Prohibition of distribution in commerce; manufacturer's -remedy.

Code of Federal Regulations, 2010 CFR

2010-07-01

... commerce; manufacturer's -remedy. 204.57-9 Section 204.57-9 Protection of Environment ENVIRONMENTAL... Portable Air Compressors § 204.57-9 Prohibition of distribution in commerce; manufacturer's -remedy. (a... noise emission tests conducted pursuant to this Subpart B may not be distributed in commerce until...

31 CFR 537.204 - Prohibited new investment in Burma.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Prohibited new investment in Burma. 537.204 Section 537.204 Money and Finance: Treasury Regulations Relating to Money and Finance... Prohibitions § 537.204 Prohibited new investment in Burma. Except as otherwise authorized, new investment, as...

48 CFR 204.7107 - Contract accounting classification reference number (ACRN) and agency accounting identifier (AAI).

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Contract accounting classification reference number (ACRN) and agency accounting identifier (AAI). 204.7107 Section 204.7107 Federal... ADMINISTRATIVE MATTERS Uniform Contract Line Item Numbering System 204.7107 Contract accounting classification...

50 CFR 226.204 - Critical habitat for Sacramento winter-run chinook salmon.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 50 Wildlife and Fisheries 10 2014-10-01 2014-10-01 false Critical habitat for Sacramento winter-run chinook salmon. 226.204 Section 226.204 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE... HABITAT § 226.204 Critical habitat for Sacramento winter-run chinook salmon. The following waterways...

50 CFR 226.204 - Critical habitat for Sacramento winter-run chinook salmon.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 50 Wildlife and Fisheries 10 2013-10-01 2013-10-01 false Critical habitat for Sacramento winter-run chinook salmon. 226.204 Section 226.204 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE... HABITAT § 226.204 Critical habitat for Sacramento winter-run chinook salmon. The following waterways...

46 CFR 180.204 - Survival craft-vessels operating on coastwise routes.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft-vessels operating on coastwise routes. 180.204 Section 180.204 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL... Craft § 180.204 Survival craft—vessels operating on coastwise routes. (a) Except as allowed by paragraph...

42 CFR 56.204 - Grant evaluation and award.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Grant evaluation and award. 56.204 Section 56.204 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR MIGRANT HEALTH SERVICES Grants for Planning and Developing Migrant Health Centers § 56.204 Grant evaluation and...

22 CFR 204.43 - Governing law.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Governing law. 204.43 Section 204.43 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HOUSING GUARANTY STANDARD TERMS AND CONDITIONS Administration § 204.43 Governing law. This Guaranty shall be governed by and construed in accordance with the laws of...

22 CFR 204.43 - Governing law.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Governing law. 204.43 Section 204.43 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HOUSING GUARANTY STANDARD TERMS AND CONDITIONS Administration § 204.43 Governing law. This Guaranty shall be governed by and construed in accordance with the laws of...

22 CFR 204.43 - Governing law.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Governing law. 204.43 Section 204.43 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HOUSING GUARANTY STANDARD TERMS AND CONDITIONS Administration § 204.43 Governing law. This Guaranty shall be governed by and construed in accordance with the laws of...

22 CFR 204.43 - Governing law.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Governing law. 204.43 Section 204.43 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HOUSING GUARANTY STANDARD TERMS AND CONDITIONS Administration § 204.43 Governing law. This Guaranty shall be governed by and construed in accordance with the laws of...

21 CFR 522.204 - Boldenone.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Boldenone. 522.204 Section 522.204 Food and Drugs..., AND RELATED PRODUCTS IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS § 522.204 Boldenone. (a) Specifications. Each milliliter of solution contains 25 or 50 milligrams (mg) boldenone undecylenate. (b) Sponsor...

21 CFR 522.204 - Boldenone.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 6 2013-04-01 2013-04-01 false Boldenone. 522.204 Section 522.204 Food and Drugs..., AND RELATED PRODUCTS IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS § 522.204 Boldenone. (a) Specifications. Each milliliter of solution contains 25 or 50 milligrams (mg) boldenone undecylenate. (b) Sponsor...

21 CFR 522.204 - Boldenone.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 6 2011-04-01 2011-04-01 false Boldenone. 522.204 Section 522.204 Food and Drugs..., AND RELATED PRODUCTS IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS § 522.204 Boldenone. (a) Specifications. Each milliliter of solution contains 25 or 50 milligrams (mg) boldenone undecylenate. (b) Sponsor...

21 CFR 522.204 - Boldenone.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 6 2014-04-01 2014-04-01 false Boldenone. 522.204 Section 522.204 Food and Drugs..., AND RELATED PRODUCTS IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS § 522.204 Boldenone. (a) Specifications. Each milliliter of solution contains 25 or 50 milligrams (mg) boldenone undecylenate. (b) Sponsor...

21 CFR 522.204 - Boldenone.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 6 2012-04-01 2012-04-01 false Boldenone. 522.204 Section 522.204 Food and Drugs..., AND RELATED PRODUCTS IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS § 522.204 Boldenone. (a) Specifications. Each milliliter of solution contains 25 or 50 milligrams (mg) boldenone undecylenate. (b) Sponsor...

50 CFR 622.204 - At-sea observer coverage.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 50 Wildlife and Fisheries 12 2013-10-01 2013-10-01 false At-sea observer coverage. 622.204 Section 622.204 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC... Fishery of the South Atlantic Region § 622.204 At-sea observer coverage. (a) Required coverage. A vessel...

50 CFR 622.204 - At-sea observer coverage.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 50 Wildlife and Fisheries 12 2014-10-01 2014-10-01 false At-sea observer coverage. 622.204 Section 622.204 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC... Fishery of the South Atlantic Region § 622.204 At-sea observer coverage. (a) Required coverage. A vessel...

10 CFR 1050.204 - Advance approval for acceptance of gifts or decorations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Advance approval for acceptance of gifts or decorations. 1050.204 Section 1050.204 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) FOREIGN GIFTS AND DECORATIONS Guidelines for Acceptance of Foreign Gifts or Decorations § 1050.204 Advance approval for...

42 CFR 438.204 - Elements of State quality strategies.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 4 2014-10-01 2014-10-01 false Elements of State quality strategies. 438.204 Section 438.204 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Improvement § 438.204 Elements of State quality strategies. At a minimum, State strategies must include the...

42 CFR 438.204 - Elements of State quality strategies.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 4 2012-10-01 2012-10-01 false Elements of State quality strategies. 438.204 Section 438.204 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Improvement § 438.204 Elements of State quality strategies. At a minimum, State strategies must include the...

42 CFR 438.204 - Elements of State quality strategies.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 4 2013-10-01 2013-10-01 false Elements of State quality strategies. 438.204 Section 438.204 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Improvement § 438.204 Elements of State quality strategies. At a minimum, State strategies must include the...

12 CFR 204.132 - Treatment of loan strip participations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Treatment of loan strip participations. 204.132 Section 204.132 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM RESERVE REQUIREMENTS OF DEPOSITORY INSTITUTIONS (REGULATION D) Interpretations § 204.132 Treatment of loan...

12 CFR 204.127 - Nondepository participation in “Federal funds” market.

Code of Federal Regulations, 2010 CFR

2010-01-01

... market. 204.127 Section 204.127 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM RESERVE REQUIREMENTS OF DEPOSITORY INSTITUTIONS (REGULATION D) Interpretations... selling depository institution. (c) The Board regards the notice requirements set out in 12 CFR 204.126 as...

40 CFR 204.5-3 - Export exemptions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Export exemptions. 204.5-3 Section 204... NOISE EMISSION STANDARDS FOR CONSTRUCTION EQUIPMENT General Provisions § 204.5-3 Export exemptions. (a) A new product intended solely for export, and so labeled or marked on the outside of the container...

44 CFR 204.24 - Determination on request for a fire management assistance declaration.

Code of Federal Regulations, 2014 CFR

2014-10-01

... ASSISTANCE GRANT PROGRAM Declaration Process § 204.24 Determination on request for a fire management... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Determination on request for a fire management assistance declaration. 204.24 Section 204.24 Emergency Management and Assistance...

44 CFR 204.26 - Appeal of fire management assistance declaration denial.

Code of Federal Regulations, 2011 CFR

2011-10-01

... PROGRAM Declaration Process § 204.26 Appeal of fire management assistance declaration denial. (a... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Appeal of fire management assistance declaration denial. 204.26 Section 204.26 Emergency Management and Assistance FEDERAL EMERGENCY...

44 CFR 204.24 - Determination on request for a fire management assistance declaration.

Code of Federal Regulations, 2012 CFR

2012-10-01

... ASSISTANCE GRANT PROGRAM Declaration Process § 204.24 Determination on request for a fire management... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Determination on request for a fire management assistance declaration. 204.24 Section 204.24 Emergency Management and Assistance...

44 CFR 204.26 - Appeal of fire management assistance declaration denial.

Code of Federal Regulations, 2014 CFR

2014-10-01

... PROGRAM Declaration Process § 204.26 Appeal of fire management assistance declaration denial. (a... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Appeal of fire management assistance declaration denial. 204.26 Section 204.26 Emergency Management and Assistance FEDERAL EMERGENCY...

44 CFR 204.26 - Appeal of fire management assistance declaration denial.

Code of Federal Regulations, 2010 CFR

2010-10-01

... PROGRAM Declaration Process § 204.26 Appeal of fire management assistance declaration denial. (a... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Appeal of fire management assistance declaration denial. 204.26 Section 204.26 Emergency Management and Assistance FEDERAL EMERGENCY...

44 CFR 204.26 - Appeal of fire management assistance declaration denial.

Code of Federal Regulations, 2012 CFR

2012-10-01

... PROGRAM Declaration Process § 204.26 Appeal of fire management assistance declaration denial. (a... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Appeal of fire management assistance declaration denial. 204.26 Section 204.26 Emergency Management and Assistance FEDERAL EMERGENCY...

44 CFR 204.24 - Determination on request for a fire management assistance declaration.

Code of Federal Regulations, 2013 CFR

2013-10-01

... ASSISTANCE GRANT PROGRAM Declaration Process § 204.24 Determination on request for a fire management... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Determination on request for a fire management assistance declaration. 204.24 Section 204.24 Emergency Management and Assistance...

44 CFR 204.26 - Appeal of fire management assistance declaration denial.

Code of Federal Regulations, 2013 CFR

2013-10-01

... PROGRAM Declaration Process § 204.26 Appeal of fire management assistance declaration denial. (a... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Appeal of fire management assistance declaration denial. 204.26 Section 204.26 Emergency Management and Assistance FEDERAL EMERGENCY...

44 CFR 204.24 - Determination on request for a fire management assistance declaration.

Code of Federal Regulations, 2011 CFR

2011-10-01

... ASSISTANCE GRANT PROGRAM Declaration Process § 204.24 Determination on request for a fire management... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Determination on request for a fire management assistance declaration. 204.24 Section 204.24 Emergency Management and Assistance...

41 CFR 109-38.204-50 - Records of exempted motor vehicles.

Code of Federal Regulations, 2011 CFR

2011-01-01

... motor vehicles. 109-38.204-50 Section 109-38.204-50 Public Contracts and Property Management Federal... AVIATION, TRANSPORTATION, AND MOTOR VEHICLES 38-MOTOR EQUIPMENT MANAGEMENT 38.2-Registration, Identification, and Exemptions § 109-38.204-50 Records of exempted motor vehicles. The Director, Office of...

12 CFR 268.204 - Class complaints.

Code of Federal Regulations, 2011 CFR

2011-01-01

... shall notify class members of the final decision and relief awarded, if any, through the same media... 12 Banks and Banking 3 2011-01-01 2011-01-01 false Class complaints. 268.204 Section 268.204 Banks... REGARDING EQUAL OPPORTUNITY Provisions Applicable to Particular Complaints § 268.204 Class complaints. (a...

8 CFR 204.301 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Definitions. 204.301 Section 204.301 Aliens... 204.300(b), means the adoption, on or after the Convention effective date, of an alien child... child's life so that the parent's whereabouts are unknown, there is no reasonable expectation of the...

8 CFR 204.301 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Definitions. 204.301 Section 204.301 Aliens... 204.300(b), means the adoption, on or after the Convention effective date, of an alien child... child's life so that the parent's whereabouts are unknown, there is no reasonable expectation of the...

8 CFR 204.301 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Definitions. 204.301 Section 204.301 Aliens... 204.300(b), means the adoption, on or after the Convention effective date, of an alien child... child's life so that the parent's whereabouts are unknown, there is no reasonable expectation of the...

37 CFR 204.5 - Procedures for requesting access to records.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Procedures for requesting access to records. 204.5 Section 204.5 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT OFFICE AND PROCEDURES PRIVACY ACT: POLICIES AND PROCEDURES § 204.5 Procedures for...

37 CFR 204.1 - Purposes and scope.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Purposes and scope. 204.1 Section 204.1 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT OFFICE AND PROCEDURES PRIVACY ACT: POLICIES AND PROCEDURES § 204.1 Purposes and scope. The purposes of these...

37 CFR 204.7 - Request for correction or amendment of records.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Request for correction or amendment of records. 204.7 Section 204.7 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT OFFICE AND PROCEDURES PRIVACY ACT: POLICIES AND PROCEDURES § 204.7 Request for...

22 CFR 204.43 - Governing law.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Governing law. 204.43 Section 204.43 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HOUSING GUARANTY STANDARD TERMS AND CONDITIONS Administration § 204.43 Governing law. This Guaranty shall be governed by and construed in accordance with the laws of...

8 CFR 204.300 - Scope of this subpart.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Scope of this subpart. 204.300 Section 204.300 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRANT PETITIONS Intercountry Adoption of a Convention Adoptee § 204.300 Scope of this subpart. (a) Convention adoptees. This...

32 CFR 204.6 - Collections.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Collections. 204.6 Section 204.6 National... USER FEES § 204.6 Collections. (a) Collections of fees will be made in advance or simultaneously with..., and managing cash and debt collections. (b) Unless a statute provides otherwise, user fee collections...

8 CFR 204.302 - Role of service providers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Role of service providers. 204.302 Section 204.302 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRANT PETITIONS Intercountry Adoption of a Convention Adoptee § 204.302 Role of service providers. (a) Who may...

25 CFR 11.204 - Prosecutors.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 1 2014-04-01 2014-04-01 false Prosecutors. 11.204 Section 11.204 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Courts of Indian Offenses; Personnel; Administration § 11.204 Prosecutors. Except as may otherwise be...

25 CFR 11.204 - Prosecutors.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 1 2012-04-01 2011-04-01 true Prosecutors. 11.204 Section 11.204 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Courts of Indian Offenses; Personnel; Administration § 11.204 Prosecutors. Except as may otherwise be...

25 CFR 11.204 - Prosecutors.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 1 2011-04-01 2011-04-01 false Prosecutors. 11.204 Section 11.204 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Courts of Indian Offenses; Personnel; Administration § 11.204 Prosecutors. Except as may otherwise be...

25 CFR 11.204 - Prosecutors.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 1 2013-04-01 2013-04-01 false Prosecutors. 11.204 Section 11.204 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Courts of Indian Offenses; Personnel; Administration § 11.204 Prosecutors. Except as may otherwise be...

10 CFR 835.204 - Planned special exposures.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Planned special exposures. 835.204 Section 835.204 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Standards for Internal and External Exposure § 835.204 Planned special exposures. (a) A planned special exposure may be authorized for a radiological worker to...

10 CFR 835.204 - Planned special exposures.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Planned special exposures. 835.204 Section 835.204 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Standards for Internal and External Exposure § 835.204 Planned special exposures. (a) A planned special exposure may be authorized for a radiological worker to...

10 CFR 835.204 - Planned special exposures.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Planned special exposures. 835.204 Section 835.204 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Standards for Internal and External Exposure § 835.204 Planned special exposures. (a) A planned special exposure may be authorized for a radiological worker to...

10 CFR 835.204 - Planned special exposures.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Planned special exposures. 835.204 Section 835.204 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Standards for Internal and External Exposure § 835.204 Planned special exposures. (a) A planned special exposure may be authorized for a radiological worker to...

48 CFR 28.204 - Alternatives in lieu of corporate or individual sureties.

Code of Federal Regulations, 2013 CFR

2013-10-01

....204-3 instead of a corporate or individual surety for the bond. When any of those types of security... corporate or individual sureties. 28.204 Section 28.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Sureties and Other Security for...

48 CFR 2928.204 - Alternatives in lieu of corporate or individual sureties.

Code of Federal Regulations, 2010 CFR

2010-10-01

... corporate or individual sureties. 2928.204 Section 2928.204 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Sureties and Other Security for Bonds 2928.204 Alternatives in lieu of corporate or individual sureties. Upon receipt of any of the...

48 CFR 28.204 - Alternatives in lieu of corporate or individual sureties.

Code of Federal Regulations, 2010 CFR

2010-10-01

....204-3 instead of a corporate or individual surety for the bond. When any of those types of security... corporate or individual sureties. 28.204 Section 28.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Sureties and Other Security for...

48 CFR 2928.204 - Alternatives in lieu of corporate or individual sureties.

Code of Federal Regulations, 2011 CFR

2011-10-01

... corporate or individual sureties. 2928.204 Section 2928.204 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Sureties and Other Security for Bonds 2928.204 Alternatives in lieu of corporate or individual sureties. Upon receipt of any of the...

48 CFR 28.204 - Alternatives in lieu of corporate or individual sureties.

Code of Federal Regulations, 2011 CFR

2011-10-01

....204-3 instead of a corporate or individual surety for the bond. When any of those types of security... corporate or individual sureties. 28.204 Section 28.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Sureties and Other Security for...

48 CFR 28.204 - Alternatives in lieu of corporate or individual sureties.

Code of Federal Regulations, 2012 CFR

2012-10-01

....204-3 instead of a corporate or individual surety for the bond. When any of those types of security... corporate or individual sureties. 28.204 Section 28.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Sureties and Other Security for...

48 CFR 2928.204 - Alternatives in lieu of corporate or individual sureties.

Code of Federal Regulations, 2012 CFR

2012-10-01

... corporate or individual sureties. 2928.204 Section 2928.204 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Sureties and Other Security for Bonds 2928.204 Alternatives in lieu of corporate or individual sureties. Upon receipt of any of the...

48 CFR 2928.204 - Alternatives in lieu of corporate or individual sureties.

Code of Federal Regulations, 2013 CFR

2013-10-01

... corporate or individual sureties. 2928.204 Section 2928.204 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Sureties and Other Security for Bonds 2928.204 Alternatives in lieu of corporate or individual sureties. Upon receipt of any of the...

48 CFR 2928.204 - Alternatives in lieu of corporate or individual sureties.

Code of Federal Regulations, 2014 CFR

2014-10-01

... corporate or individual sureties. 2928.204 Section 2928.204 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Sureties and Other Security for Bonds 2928.204 Alternatives in lieu of corporate or individual sureties. Upon receipt of any of the...

48 CFR 28.204 - Alternatives in lieu of corporate or individual sureties.

Code of Federal Regulations, 2014 CFR

2014-10-01

....204-3 instead of a corporate or individual surety for the bond. When any of those types of security... corporate or individual sureties. 28.204 Section 28.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Sureties and Other Security for...

49 CFR 571.204 - Standard No. 204; Steering control rearward displacement.

Code of Federal Regulations, 2012 CFR

2012-10-01

... displacement. 571.204 Section 571.204 Transportation Other Regulations Relating to Transportation (Continued... displacement. S1. Purpose and scope. This standard specifies requirements limiting the rearward displacement of... displacement shall be measured relative to an undisturbed point on the vehicle and shall represent the maximum...

49 CFR 571.204 - Standard No. 204; Steering control rearward displacement.

Code of Federal Regulations, 2014 CFR

2014-10-01

... displacement. 571.204 Section 571.204 Transportation Other Regulations Relating to Transportation (Continued... displacement. S1. Purpose and scope. This standard specifies requirements limiting the rearward displacement of... displacement shall be measured relative to an undisturbed point on the vehicle and shall represent the maximum...

49 CFR 571.204 - Standard No. 204; Steering control rearward displacement.

Code of Federal Regulations, 2010 CFR

2010-10-01

... displacement. 571.204 Section 571.204 Transportation Other Regulations Relating to Transportation (Continued... displacement. S1. Purpose and scope. This standard specifies requirements limiting the rearward displacement of... displacement shall be measured relative to an undisturbed point on the vehicle and shall represent the maximum...

49 CFR 571.204 - Standard No. 204; Steering control rearward displacement.

Code of Federal Regulations, 2011 CFR

2011-10-01

... displacement. 571.204 Section 571.204 Transportation Other Regulations Relating to Transportation (Continued... displacement. S1. Purpose and scope. This standard specifies requirements limiting the rearward displacement of... displacement shall be measured relative to an undisturbed point on the vehicle and shall represent the maximum...

49 CFR 571.204 - Standard No. 204; Steering control rearward displacement.

Code of Federal Regulations, 2013 CFR

2013-10-01

... displacement. 571.204 Section 571.204 Transportation Other Regulations Relating to Transportation (Continued... displacement. S1. Purpose and scope. This standard specifies requirements limiting the rearward displacement of... displacement shall be measured relative to an undisturbed point on the vehicle and shall represent the maximum...

48 CFR 2903.204 - Treatment of violations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Treatment of violations. 2903.204 Section 2903.204 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL IMPROPER....204 Treatment of violations. Any suspected violations of FAR subpart 3.2 and the clause at FAR 52.203...

48 CFR 3017.204-90 - Detention Facilities and Services (ICE).

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Detention Facilities and Services (ICE). 3017.204-90 Section 3017.204-90 Federal Acquisition Regulations System DEPARTMENT OF... SPECIAL CONTRACTING METHODS Options. 3017.204-90 Detention Facilities and Services (ICE). The ICE Head of...

48 CFR 3017.204-90 - Detention Facilities and Services (ICE).

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 7 2013-10-01 2012-10-01 true Detention Facilities and Services (ICE). 3017.204-90 Section 3017.204-90 Federal Acquisition Regulations System DEPARTMENT OF... SPECIAL CONTRACTING METHODS Options 3017.204-90 Detention Facilities and Services (ICE). The ICE Head of...

48 CFR 3017.204-90 - Detention Facilities and Services (ICE).

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Detention Facilities and Services (ICE). 3017.204-90 Section 3017.204-90 Federal Acquisition Regulations System DEPARTMENT OF... SPECIAL CONTRACTING METHODS Options. 3017.204-90 Detention Facilities and Services (ICE). The ICE Head of...

48 CFR 3017.204-90 - Detention Facilities and Services (ICE).

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 7 2014-10-01 2014-10-01 false Detention Facilities and Services (ICE). 3017.204-90 Section 3017.204-90 Federal Acquisition Regulations System DEPARTMENT OF... SPECIAL CONTRACTING METHODS Options 3017.204-90 Detention Facilities and Services (ICE). The ICE Head of...

48 CFR 3017.204-90 - Detention Facilities and Services (ICE).

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 7 2012-10-01 2012-10-01 false Detention Facilities and Services (ICE). 3017.204-90 Section 3017.204-90 Federal Acquisition Regulations System DEPARTMENT OF... SPECIAL CONTRACTING METHODS Options 3017.204-90 Detention Facilities and Services (ICE). The ICE Head of...

24 CFR 51.204 - HUD-assisted hazardous facilities.

Code of Federal Regulations, 2014 CFR

2014-04-01

... area where people may congregate or be present. The mitigating measures listed in § 51.205 may be taken.... 51.204 Section 51.204 Housing and Urban Development Office of the Secretary, Department of Housing... Hazardous Operations Handling Conventional Fuels or Chemicals of an Explosive or Flammable Nature § 51.204...

24 CFR 51.204 - HUD-assisted hazardous facilities.

Code of Federal Regulations, 2011 CFR

2011-04-01

... area where people may congregate or be present. The mitigating measures listed in § 51.205 may be taken.... 51.204 Section 51.204 Housing and Urban Development Office of the Secretary, Department of Housing... Hazardous Operations Handling Conventional Fuels or Chemicals of an Explosive or Flammable Nature § 51.204...

24 CFR 51.204 - HUD-assisted hazardous facilities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... area where people may congregate or be present. The mitigating measures listed in § 51.205 may be taken.... 51.204 Section 51.204 Housing and Urban Development Office of the Secretary, Department of Housing... Hazardous Operations Handling Conventional Fuels or Chemicals of an Explosive or Flammable Nature § 51.204...

24 CFR 51.204 - HUD-assisted hazardous facilities.

Code of Federal Regulations, 2013 CFR

2013-04-01

... area where people may congregate or be present. The mitigating measures listed in § 51.205 may be taken.... 51.204 Section 51.204 Housing and Urban Development Office of the Secretary, Department of Housing... Hazardous Operations Handling Conventional Fuels or Chemicals of an Explosive or Flammable Nature § 51.204...

24 CFR 51.204 - HUD-assisted hazardous facilities.

Code of Federal Regulations, 2012 CFR

2012-04-01

... area where people may congregate or be present. The mitigating measures listed in § 51.205 may be taken.... 51.204 Section 51.204 Housing and Urban Development Office of the Secretary, Department of Housing... Hazardous Operations Handling Conventional Fuels or Chemicals of an Explosive or Flammable Nature § 51.204...

31 CFR 800.204 - Control.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Control. 800.204 Section 800.204 Money... FOREIGN PERSONS Definitions § 800.204 Control. (a) The term control means the power, direct or indirect... in paragraphs (a)(1) through (9) of this section. (b) In examining questions of control in situations...

31 CFR 800.204 - Control.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Control. 800.204 Section 800.204 Money... FOREIGN PERSONS Definitions § 800.204 Control. (a) The term control means the power, direct or indirect... in paragraphs (a)(1) through (9) of this section. (b) In examining questions of control in situations...

31 CFR 800.204 - Control.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Control. 800.204 Section 800.204 Money... FOREIGN PERSONS Definitions § 800.204 Control. (a) The term control means the power, direct or indirect... in paragraphs (a)(1) through (9) of this section. (b) In examining questions of control in situations...

31 CFR 800.204 - Control.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Control. 800.204 Section 800.204... FOREIGN PERSONS Definitions § 800.204 Control. (a) The term control means the power, direct or indirect... in paragraphs (a)(1) through (9) of this section. (b) In examining questions of control in situations...

31 CFR 800.204 - Control.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Control. 800.204 Section 800.204 Money... FOREIGN PERSONS Definitions § 800.204 Control. (a) The term control means the power, direct or indirect... in paragraphs (a)(1) through (9) of this section. (b) In examining questions of control in situations...

5 CFR 930.204 - Appointments and conditions of employment.

Code of Federal Regulations, 2014 CFR

2014-01-01

.... 930.204 Section 930.204 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL...) Administrative Law Judge Program § 930.204 Appointments and conditions of employment. Link to an amendment... administrative law judge position only with prior approval of OPM, except when it makes its selection from the...

50 CFR 216.204 - Mitigation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Mitigation. 216.204 Section 216.204... U.S. Beaufort Sea § 216.204 Mitigation. The activity identified in § 216.200(a) must be conducted in... their habitats. When conducting operations identified in § 216.200, the mitigation measures contained in...

10 CFR 830.204 - Documented safety analysis.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Documented safety analysis. 830.204 Section 830.204 Energy DEPARTMENT OF ENERGY NUCLEAR SAFETY MANAGEMENT Safety Basis Requirements § 830.204 Documented safety analysis... approval from DOE for the methodology used to prepare the documented safety analysis for the facility...

48 CFR 52.204-13 - System for Award Management Maintenance.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Management Maintenance. 52.204-13 Section 52.204-13 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.204-13 System for Award Management Maintenance. As prescribed in 4.1105(b), use the following clause: System for Award Management Maintenance (JUL 2013) (a) Definitions. As used in this clause...

41 CFR 50-204.35 - Application for variations from radiation levels.

Code of Federal Regulations, 2012 CFR

2012-07-01

... variations from radiation levels. 50-204.35 Section 50-204.35 Public Contracts and Property Management Other... FOR FEDERAL SUPPLY CONTRACTS Radiation Standards § 50-204.35 Application for variations from radiation levels. (a) In accordance with policy expressed in the Federal Radiation Council's memorandum concerning...

41 CFR 50-204.35 - Application for variations from radiation levels.

Code of Federal Regulations, 2011 CFR

2011-07-01

... variations from radiation levels. 50-204.35 Section 50-204.35 Public Contracts and Property Management Other... FOR FEDERAL SUPPLY CONTRACTS Radiation Standards § 50-204.35 Application for variations from radiation levels. (a) In accordance with policy expressed in the Federal Radiation Council's memorandum concerning...

41 CFR 50-204.35 - Application for variations from radiation levels.

Code of Federal Regulations, 2013 CFR

2013-07-01

... variations from radiation levels. 50-204.35 Section 50-204.35 Public Contracts and Property Management Other... FOR FEDERAL SUPPLY CONTRACTS Radiation Standards § 50-204.35 Application for variations from radiation levels. (a) In accordance with policy expressed in the Federal Radiation Council's memorandum concerning...

41 CFR 50-204.35 - Application for variations from radiation levels.

Code of Federal Regulations, 2014 CFR

2014-07-01

... variations from radiation levels. 50-204.35 Section 50-204.35 Public Contracts and Property Management Other... FOR FEDERAL SUPPLY CONTRACTS Radiation Standards § 50-204.35 Application for variations from radiation levels. (a) In accordance with policy expressed in the Federal Radiation Council's memorandum concerning...

29 CFR 20.4 - Determination of delinquency; notice.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 1 2010-07-01 2010-07-01 true Determination of delinquency; notice. 20.4 Section 20.4 Labor Office of the Secretary of Labor FEDERAL CLAIMS COLLECTION Disclosure of Information to Credit Reporting Agencies § 20.4 Determination of delinquency; notice. (a) The agency head (or designee...

44 CFR 204.64 - Reporting and audit requirements

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Reporting and audit requirements 204.64 Section 204.64 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FIRE MANAGEMENT ASSISTANCE GRANT PROGRAM Grant Administration § 204.64 Reporting and audit...

10 CFR 600.204 - Effect on other issuances.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Effect on other issuances. 600.204 Section 600.204 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS FINANCIAL ASSISTANCE RULES Uniform Administrative Requirements for Grants and Cooperative Agreements to State and Local Governments General § 600.204 Effect on...

48 CFR 204.7107 - Contract accounting classification reference number (ACRN) and agency accounting identifier (AAI).

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contract accounting classification reference number (ACRN) and agency accounting identifier (AAI). 204.7107 Section 204.7107 Federal... ADMINISTRATIVE MATTERS Uniform Contract Line Item Numbering System 204.7107 Contract accounting classification...

48 CFR 204.606 - Reporting data.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Reporting data. 204.606... OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Reporting 204.606 Reporting data. In addition to FAR 4.606, follow the procedures at PGI 204.606 for reporting data to FPDS. [74 FR 37644, July 29...

48 CFR 204.606 - Reporting data.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Reporting data. 204.606... OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Reporting 204.606 Reporting data. In addition to FAR 4.606, follow the procedures at PGI 204.606 for reporting data to FPDS. [74 FR 37644, July 29...

48 CFR 204.606 - Reporting data.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Reporting data. 204.606... OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Reporting 204.606 Reporting data. In addition to FAR 4.606, follow the procedures at PGI 204.606 for reporting data to FPDS. [74 FR 37644, July 29...

37 CFR 41.204 - Notice of basis for relief.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Notice of basis for relief. 41.204 Section 41.204 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE PRACTICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Patent Interferences § 41.204 Notice...

32 CFR 724.204 - Eligibility for naval discharge review.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Eligibility for naval discharge review. 724.204 Section 724.204 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL NAVAL DISCHARGE REVIEW BOARD Authority/Policy for Departmental Discharge Review § 724.204 Eligibility for naval...

32 CFR 724.204 - Eligibility for naval discharge review.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Eligibility for naval discharge review. 724.204 Section 724.204 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL NAVAL DISCHARGE REVIEW BOARD Authority/Policy for Departmental Discharge Review § 724.204 Eligibility for naval...

46 CFR 308.204 - Additional war risk protection and indemnity insurance.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 8 2013-10-01 2013-10-01 false Additional war risk protection and indemnity insurance. 308.204 Section 308.204 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.204 Additional war risk...

46 CFR 308.204 - Additional war risk protection and indemnity insurance.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 8 2011-10-01 2011-10-01 false Additional war risk protection and indemnity insurance. 308.204 Section 308.204 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.204 Additional war risk...

46 CFR 308.204 - Additional war risk protection and indemnity insurance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Additional war risk protection and indemnity insurance. 308.204 Section 308.204 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.204 Additional war risk...

46 CFR 308.204 - Additional war risk protection and indemnity insurance.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 8 2014-10-01 2014-10-01 false Additional war risk protection and indemnity insurance. 308.204 Section 308.204 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.204 Additional war risk...

46 CFR 308.204 - Additional war risk protection and indemnity insurance.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 8 2012-10-01 2012-10-01 false Additional war risk protection and indemnity insurance. 308.204 Section 308.204 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.204 Additional war risk...

34 CFR 682.204 - Maximum loan amounts.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 3 2010-07-01 2010-07-01 false Maximum loan amounts. 682.204 Section 682.204 Education..., DEPARTMENT OF EDUCATION FEDERAL FAMILY EDUCATION LOAN (FFEL) PROGRAM General Provisions § 682.204 Maximum... a full academic year, the maximum annual amount that the student may receive may not exceed the...

19 CFR 204.5 - Reports.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 3 2013-04-01 2013-04-01 false Reports. 204.5 Section 204.5 Customs Duties UNITED... ON AGRICULTURAL PROGRAMS § 204.5 Reports. After completion of its investigation, the Commission will transmit to the President a report of the results thereof, including its findings and recommendations based...

19 CFR 204.5 - Reports.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 3 2010-04-01 2010-04-01 false Reports. 204.5 Section 204.5 Customs Duties UNITED... ON AGRICULTURAL PROGRAMS § 204.5 Reports. After completion of its investigation, the Commission will transmit to the President a report of the results thereof, including its findings and recommendations based...

19 CFR 204.5 - Reports.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 3 2014-04-01 2014-04-01 false Reports. 204.5 Section 204.5 Customs Duties UNITED... ON AGRICULTURAL PROGRAMS § 204.5 Reports. After completion of its investigation, the Commission will transmit to the President a report of the results thereof, including its findings and recommendations based...

41 CFR 50-204.1 - Scope and application.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 41 Public Contracts and Property Management 1 2011-07-01 2009-07-01 true Scope and application. 50-204.1 Section 50-204.1 Public Contracts and Property Management Other Provisions Relating to Public... Scope and Application § 50-204.1 Scope and application. (a) The Walsh-Healey Public Contracts Act...

41 CFR 50-204.1 - Scope and application.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 41 Public Contracts and Property Management 1 2012-07-01 2009-07-01 true Scope and application. 50-204.1 Section 50-204.1 Public Contracts and Property Management Other Provisions Relating to Public... Scope and Application § 50-204.1 Scope and application. (a) The Walsh-Healey Public Contracts Act...

41 CFR 50-204.1a - Variances.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Variances. 50-204.1a Section 50-204.1a Public Contracts and Property Management Other Provisions Relating to Public Contracts PUBLIC CONTRACTS, DEPARTMENT OF LABOR 204-SAFETY AND HEALTH STANDARDS FOR FEDERAL SUPPLY CONTRACTS Scope...

41 CFR 50-204.1a - Variances.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 41 Public Contracts and Property Management 1 2013-07-01 2013-07-01 false Variances. 50-204.1a Section 50-204.1a Public Contracts and Property Management Other Provisions Relating to Public Contracts PUBLIC CONTRACTS, DEPARTMENT OF LABOR 204-SAFETY AND HEALTH STANDARDS FOR FEDERAL SUPPLY CONTRACTS Scope...

41 CFR 50-204.1 - Scope and application.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 41 Public Contracts and Property Management 1 2013-07-01 2013-07-01 false Scope and application. 50-204.1 Section 50-204.1 Public Contracts and Property Management Other Provisions Relating to... CONTRACTS Scope and Application § 50-204.1 Scope and application. (a) The Walsh-Healey Public Contracts Act...

41 CFR 50-204.1a - Variances.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 41 Public Contracts and Property Management 1 2011-07-01 2009-07-01 true Variances. 50-204.1a Section 50-204.1a Public Contracts and Property Management Other Provisions Relating to Public Contracts PUBLIC CONTRACTS, DEPARTMENT OF LABOR 204-SAFETY AND HEALTH STANDARDS FOR FEDERAL SUPPLY CONTRACTS Scope...

41 CFR 50-204.1a - Variances.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 41 Public Contracts and Property Management 1 2012-07-01 2009-07-01 true Variances. 50-204.1a Section 50-204.1a Public Contracts and Property Management Other Provisions Relating to Public Contracts PUBLIC CONTRACTS, DEPARTMENT OF LABOR 204-SAFETY AND HEALTH STANDARDS FOR FEDERAL SUPPLY CONTRACTS Scope...

41 CFR 50-204.1 - Scope and application.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 41 Public Contracts and Property Management 1 2014-07-01 2014-07-01 false Scope and application. 50-204.1 Section 50-204.1 Public Contracts and Property Management Other Provisions Relating to... CONTRACTS Scope and Application § 50-204.1 Scope and application. (a) The Walsh-Healey Public Contracts Act...

41 CFR 50-204.1 - Scope and application.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Scope and application. 50-204.1 Section 50-204.1 Public Contracts and Property Management Other Provisions Relating to Public... Scope and Application § 50-204.1 Scope and application. (a) The Walsh-Healey Public Contracts Act...

41 CFR 50-204.1a - Variances.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 41 Public Contracts and Property Management 1 2014-07-01 2014-07-01 false Variances. 50-204.1a Section 50-204.1a Public Contracts and Property Management Other Provisions Relating to Public Contracts PUBLIC CONTRACTS, DEPARTMENT OF LABOR 204-SAFETY AND HEALTH STANDARDS FOR FEDERAL SUPPLY CONTRACTS Scope...

14 CFR 1212.204 - Fees.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Fees. 1212.204 Section 1212.204 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PRIVACY ACT-NASA REGULATIONS Access to Records § 1212.204 Fees. (a) Fees will not be charged for: (1) Search for a retrieval of the requesting...

14 CFR 1212.204 - Fees.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Fees. 1212.204 Section 1212.204 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PRIVACY ACT-NASA REGULATIONS Access to Records § 1212.204 Fees. (a) Fees will not be charged for: (1) Search for a retrieval of the requesting...

12 CFR 204.3 - Reporting and location.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Reporting and location. 204.3 Section 204.3... REQUIREMENTS OF DEPOSITORY INSTITUTIONS (REGULATION D) § 204.3 Reporting and location. (a) Every depository... corporation is located in the Federal Reserve District that contains the location specified in the institution...

13 CFR 400.204 - Loan terms.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 13 Business Credit and Assistance 1 2012-01-01 2012-01-01 false Loan terms. 400.204 Section 400.204 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.204 Loan terms. (a) All loans guaranteed under the Program shall be...

13 CFR 400.204 - Loan terms.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 13 Business Credit and Assistance 1 2014-01-01 2014-01-01 false Loan terms. 400.204 Section 400.204 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.204 Loan terms. (a) All loans guaranteed under the Program shall be...

13 CFR 400.204 - Loan terms.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false Loan terms. 400.204 Section 400.204 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.204 Loan terms. (a) All loans guaranteed under the Program shall be...

13 CFR 400.204 - Loan terms.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Loan terms. 400.204 Section 400.204 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.204 Loan terms. (a) All loans guaranteed under the Program shall be...

13 CFR 400.204 - Loan terms.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false Loan terms. 400.204 Section 400.204 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.204 Loan terms. (a) All loans guaranteed under the Program shall be...

48 CFR 204.606 - Reporting data.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Reporting data. 204.606... OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Reporting 204.606 Reporting data. In addition to FAR 4.606, follow the procedures at PGI 204.606 for reporting data to FPDS. [74 FR 37644, July 29...

48 CFR 204.606 - Reporting data.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Reporting data. 204.606... OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Reporting 204.606 Reporting data. In addition to FAR 4.606, follow the procedures at PGI 204.606 for reporting data to FPDS. [74 FR 37644, July 29...

40 CFR 204.54 - Test procedures.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Test procedures. 204.54 Section 204.54... STANDARDS FOR CONSTRUCTION EQUIPMENT Portable Air Compressors § 204.54 Test procedures. (a) General. This... which the test is conducted. (b) Test site description. The location for measuring noise employed during...

17 CFR 204.55 - Change in notification to Financial Management Service.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false Change in notification to Financial Management Service. 204.55 Section 204.55 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION RULES RELATING TO DEBT COLLECTION Tax Refund Offset § 204.55 Change in notification to...

41 CFR 50-204.29 - Waste disposal.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Waste disposal. 50-204.29 Section 50-204.29 Public Contracts and Property Management Other Provisions Relating to Public Contracts... Radiation Standards § 50-204.29 Waste disposal. No employer shall dispose of radioactive material except by...

32 CFR 204.9 - Schedule of fees and rates.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false Schedule of fees and rates. 204.9 Section 204.9 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS USER FEES § 204.9 Schedule of fees and rates. (a) Schedule of fees and rates. (1) This schedule...

32 CFR 204.5 - Fees.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false Fees. 204.5 Section 204.5 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS USER FEES § 204.5 Fees. (a) General. (1) All fees shall be based on full cost to the U.S. Government or market...

41 CFR 50-204.36 - Radiation standards for mining.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Radiation standards for mining. 50-204.36 Section 50-204.36 Public Contracts and Property Management Other Provisions Relating to Public Contracts PUBLIC CONTRACTS, DEPARTMENT OF LABOR 204-SAFETY AND HEALTH STANDARDS FOR FEDERAL SUPPLY CONTRACTS Radiation Standards § 50...

41 CFR 50-204.36 - Radiation standards for mining.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 41 Public Contracts and Property Management 1 2012-07-01 2009-07-01 true Radiation standards for mining. 50-204.36 Section 50-204.36 Public Contracts and Property Management Other Provisions Relating to Public Contracts PUBLIC CONTRACTS, DEPARTMENT OF LABOR 204-SAFETY AND HEALTH STANDARDS FOR FEDERAL SUPPLY CONTRACTS Radiation Standards § 50...

41 CFR 50-204.36 - Radiation standards for mining.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 41 Public Contracts and Property Management 1 2011-07-01 2009-07-01 true Radiation standards for mining. 50-204.36 Section 50-204.36 Public Contracts and Property Management Other Provisions Relating to Public Contracts PUBLIC CONTRACTS, DEPARTMENT OF LABOR 204-SAFETY AND HEALTH STANDARDS FOR FEDERAL SUPPLY CONTRACTS Radiation Standards § 50...

17 CFR 204.7 - Hearing.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false Hearing. 204.7 Section 204.7... Administrative Offset § 204.7 Hearing. (a) A debtor will be provided a reasonable opportunity for an oral hearing... documentary evidence. (b) In cases where an oral hearing is provided to the debtor, the Commission's designee...

77 FR 2089 - Proposed Information Collection Request of the ETA 204, Experience Rating Report; Comment Request...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-13

... DEPARTMENT OF LABOR Proposed Information Collection Request of the ETA 204, Experience Rating.... Background: The data submitted annually on the ETA-204 report enables the Employment and Training... systems. Used in conjunction with other data, the ETA-204 assists in determining the effects of certain...

42 CFR 425.204 - Content of the application.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 3 2014-10-01 2014-10-01 false Content of the application. 425.204 Section 425.204 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM (CONTINUED) MEDICARE SHARED SAVINGS PROGRAM Application Procedures and Participation Agreement § 425.204 Content of the...

41 CFR 50-204.8 - Use of compressed air.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 41 Public Contracts and Property Management 1 2013-07-01 2013-07-01 false Use of compressed air. 50-204.8 Section 50-204.8 Public Contracts and Property Management Other Provisions Relating to... CONTRACTS General Safety and Health Standards § 50-204.8 Use of compressed air. Compressed air shall not be...

41 CFR 50-204.8 - Use of compressed air.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 41 Public Contracts and Property Management 1 2014-07-01 2014-07-01 false Use of compressed air. 50-204.8 Section 50-204.8 Public Contracts and Property Management Other Provisions Relating to... CONTRACTS General Safety and Health Standards § 50-204.8 Use of compressed air. Compressed air shall not be...

40 CFR 204.3 - Number and gender.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Number and gender. 204.3 Section 204.3... STANDARDS FOR CONSTRUCTION EQUIPMENT General Provisions § 204.3 Number and gender. As used in this part, words in the singular shall be deemed to import the plural, and words in the masculine gender shall be...

40 CFR 204.3 - Number and gender.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Number and gender. 204.3 Section 204.3... STANDARDS FOR CONSTRUCTION EQUIPMENT General Provisions § 204.3 Number and gender. As used in this part, words in the singular shall be deemed to import the plural, and words in the masculine gender shall be...

40 CFR 204.3 - Number and gender.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Number and gender. 204.3 Section 204.3... STANDARDS FOR CONSTRUCTION EQUIPMENT General Provisions § 204.3 Number and gender. As used in this part, words in the singular shall be deemed to import the plural, and words in the masculine gender shall be...

40 CFR 204.3 - Number and gender.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Number and gender. 204.3 Section 204.3... STANDARDS FOR CONSTRUCTION EQUIPMENT General Provisions § 204.3 Number and gender. As used in this part, words in the singular shall be deemed to import the plural, and words in the masculine gender shall be...

40 CFR 204.3 - Number and gender.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Number and gender. 204.3 Section 204.3... STANDARDS FOR CONSTRUCTION EQUIPMENT General Provisions § 204.3 Number and gender. As used in this part, words in the singular shall be deemed to import the plural, and words in the masculine gender shall be...

42 CFR 51c.204 - Grant evaluation and award.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Grant evaluation and award. 51c.204 Section 51c.204 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR COMMUNITY HEALTH SERVICES Grants for Planning and Developing Community Health Centers § 51c.204 Grant evaluation...

42 CFR 51c.204 - Grant evaluation and award.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Grant evaluation and award. 51c.204 Section 51c.204 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR COMMUNITY HEALTH SERVICES Grants for Planning and Developing Community Health Centers § 51c.204 Grant evaluation...

5 CFR 892.204 - How do I waive participation in premium conversion before the benefit first becomes effective?

Code of Federal Regulations, 2010 CFR

2010-01-01

... conversion before the benefit first becomes effective? 892.204 Section 892.204 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL FLEXIBLE BENEFITS PLAN: PRE-TAX PAYMENT OF HEALTH BENEFITS PREMIUMS Eligibility and Participation § 892.204 How do I...

44 CFR 204.23 - Processing a request for a fire management assistance declaration.

Code of Federal Regulations, 2011 CFR

2011-10-01

... ASSISTANCE GRANT PROGRAM Declaration Process § 204.23 Processing a request for a fire management assistance... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Processing a request for a fire management assistance declaration. 204.23 Section 204.23 Emergency Management and Assistance...

44 CFR 204.25 - FEMA-State agreement for fire management assistance grant program.

Code of Federal Regulations, 2010 CFR

2010-10-01

... GRANT PROGRAM Declaration Process § 204.25 FEMA-State agreement for fire management assistance grant... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false FEMA-State agreement for fire management assistance grant program. 204.25 Section 204.25 Emergency Management and Assistance FEDERAL...

44 CFR 204.25 - FEMA-State agreement for fire management assistance grant program.

Code of Federal Regulations, 2014 CFR

2014-10-01

... GRANT PROGRAM Declaration Process § 204.25 FEMA-State agreement for fire management assistance grant... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false FEMA-State agreement for fire management assistance grant program. 204.25 Section 204.25 Emergency Management and Assistance FEDERAL...

44 CFR 204.25 - FEMA-State agreement for fire management assistance grant program.

Code of Federal Regulations, 2011 CFR

2011-10-01

... GRANT PROGRAM Declaration Process § 204.25 FEMA-State agreement for fire management assistance grant... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false FEMA-State agreement for fire management assistance grant program. 204.25 Section 204.25 Emergency Management and Assistance FEDERAL...

44 CFR 204.25 - FEMA-State agreement for fire management assistance grant program.

Code of Federal Regulations, 2012 CFR

2012-10-01

... GRANT PROGRAM Declaration Process § 204.25 FEMA-State agreement for fire management assistance grant... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true FEMA-State agreement for fire management assistance grant program. 204.25 Section 204.25 Emergency Management and Assistance FEDERAL...

44 CFR 204.23 - Processing a request for a fire management assistance declaration.

Code of Federal Regulations, 2012 CFR

2012-10-01

... ASSISTANCE GRANT PROGRAM Declaration Process § 204.23 Processing a request for a fire management assistance... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Processing a request for a fire management assistance declaration. 204.23 Section 204.23 Emergency Management and Assistance...

44 CFR 204.23 - Processing a request for a fire management assistance declaration.

Code of Federal Regulations, 2014 CFR

2014-10-01

... ASSISTANCE GRANT PROGRAM Declaration Process § 204.23 Processing a request for a fire management assistance... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Processing a request for a fire management assistance declaration. 204.23 Section 204.23 Emergency Management and Assistance...

44 CFR 204.23 - Processing a request for a fire management assistance declaration.

Code of Federal Regulations, 2013 CFR

2013-10-01

... ASSISTANCE GRANT PROGRAM Declaration Process § 204.23 Processing a request for a fire management assistance... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Processing a request for a fire management assistance declaration. 204.23 Section 204.23 Emergency Management and Assistance...

44 CFR 204.25 - FEMA-State agreement for fire management assistance grant program.

Code of Federal Regulations, 2013 CFR

2013-10-01

... GRANT PROGRAM Declaration Process § 204.25 FEMA-State agreement for fire management assistance grant... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false FEMA-State agreement for fire management assistance grant program. 204.25 Section 204.25 Emergency Management and Assistance FEDERAL...

48 CFR 52.204-5 - Women-Owned Business (Other Than Small Business).

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Women-Owned Business (Other Than Small Business). 52.204-5 Section 52.204-5 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.204-5 Women-Owned Business (Other Than Small Business). As prescribed in 4.607(b...

37 CFR 204.8 - Appeal of refusal to correct or amend an individual's record.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Appeal of refusal to correct or amend an individual's record. 204.8 Section 204.8 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT OFFICE AND PROCEDURES PRIVACY ACT: POLICIES AND PROCEDURES § 204.8...

5 CFR 2606.204 - Request for review of an initial denial of access.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Request for review of an initial denial of access. 2606.204 Section 2606.204 Administrative Personnel OFFICE OF GOVERNMENT ETHICS ORGANIZATION AND PROCEDURES PRIVACY ACT RULES Access to Records and Accounting of Disclosures § 2606.204...

22 CFR 20.4 - Retirement benefits.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Retirement benefits. 20.4 Section 20.4 Foreign Relations DEPARTMENT OF STATE PERSONNEL BENEFITS FOR CERTAIN FORMER SPOUSES § 20.4 Retirement benefits. (a) Type of benefits. (1) A former spouse who meets the qualification requirements of § 20.3 is entitled to...

22 CFR 20.4 - Retirement benefits.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Retirement benefits. 20.4 Section 20.4 Foreign Relations DEPARTMENT OF STATE PERSONNEL BENEFITS FOR CERTAIN FORMER SPOUSES § 20.4 Retirement benefits. (a) Type of benefits. (1) A former spouse who meets the qualification requirements of § 20.3 is entitled to...

22 CFR 20.4 - Retirement benefits.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Retirement benefits. 20.4 Section 20.4 Foreign Relations DEPARTMENT OF STATE PERSONNEL BENEFITS FOR CERTAIN FORMER SPOUSES § 20.4 Retirement benefits. (a) Type of benefits. (1) A former spouse who meets the qualification requirements of § 20.3 is entitled to...

22 CFR 20.4 - Retirement benefits.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Retirement benefits. 20.4 Section 20.4 Foreign Relations DEPARTMENT OF STATE PERSONNEL BENEFITS FOR CERTAIN FORMER SPOUSES § 20.4 Retirement benefits. (a) Type of benefits. (1) A former spouse who meets the qualification requirements of § 20.3 is entitled to...

22 CFR 20.4 - Retirement benefits.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Retirement benefits. 20.4 Section 20.4 Foreign Relations DEPARTMENT OF STATE PERSONNEL BENEFITS FOR CERTAIN FORMER SPOUSES § 20.4 Retirement benefits. (a) Type of benefits. (1) A former spouse who meets the qualification requirements of § 20.3 is entitled to...

42 CFR 59.204 - Application for a grant.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Application for a grant. 59.204 Section 59.204 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Grants for Family Planning Service Training § 59.204 Application for a grant. (a) An...

42 CFR 59.204 - Application for a grant.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Application for a grant. 59.204 Section 59.204 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Grants for Family Planning Service Training § 59.204 Application for a grant. (a) An...

42 CFR 59.204 - Application for a grant.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Application for a grant. 59.204 Section 59.204 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Grants for Family Planning Service Training § 59.204 Application for a grant. (a) An...

42 CFR 59.204 - Application for a grant.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Application for a grant. 59.204 Section 59.204 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Grants for Family Planning Service Training § 59.204 Application for a grant. (a) An...

42 CFR 59.204 - Application for a grant.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Application for a grant. 59.204 Section 59.204 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Grants for Family Planning Service Training § 59.204 Application for a grant. (a) An...

12 CFR 204.133 - Multiple savings deposits treated as a transaction account.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 2 2012-01-01 2012-01-01 false Multiple savings deposits treated as a transaction account. 204.133 Section 204.133 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF...) Interpretations § 204.133 Multiple savings deposits treated as a transaction account. (a) Authority. Under section...

12 CFR 204.133 - Multiple savings deposits treated as a transaction account.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 2 2014-01-01 2014-01-01 false Multiple savings deposits treated as a transaction account. 204.133 Section 204.133 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF...) Interpretations § 204.133 Multiple savings deposits treated as a transaction account. (a) Authority. Under section...

8 CFR 204.310 - Filing requirements for Form I-800A.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Filing requirements for Form I-800A. 204.310 Section 204.310 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRANT PETITIONS Intercountry Adoption of a Convention Adoptee § 204.310 Filing requirements for Form I...

8 CFR 204.306 - Classification as an immediate relative based on a Convention adoption.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Classification as an immediate relative based on a Convention adoption. 204.306 Section 204.306 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRANT PETITIONS Intercountry Adoption of a Convention Adoptee § 204...

30 CFR 204.212 - What if I took relief for which I was ineligible?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What if I took relief for which I was ineligible? 204.212 Section 204.212 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT ALTERNATIVES FOR MARGINAL PROPERTIES Accounting and Auditing Relief § 204.212...

30 CFR 204.204 - What accounting and auditing relief will MMS not allow?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What accounting and auditing relief will MMS... INTERIOR MINERALS REVENUE MANAGEMENT ALTERNATIVES FOR MARGINAL PROPERTIES Accounting and Auditing Relief § 204.204 What accounting and auditing relief will MMS not allow? MMS will not approve your request for...