Leucine 208 in human histamine N-methyltransferase emerges as a hotspot for protein stability rationalizing the role of the L208P variant in intellectual disability.

PubMed

Tongsook, Chanakan; Niederhauser, Johannes; Kronegger, Elena; Straganz, Grit; Macheroux, Peter

2017-01-01

The degradation of histamine catalyzed by the SAM-dependent histamine N-methyltransferase (HNMT) is critically important for the maintenance of neurological processes. Recently, two mutations in the encoding human gene were reported to give rise to dysfunctional protein variants (G60D and L208P) leading to intellectual disability. In the present study, we have expressed eight L208 variants with either apolar (L208F and L208V), polar (L208N and L208T) or charged (L208D, L208H, L208K and L208R) amino acids to define the impact of side chain variations on protein structure and function. We found that the variants L208N, L208T, L208D and L208H were severely compromised in their stability. The other four variants were obtained in lower amounts in the order wild-type HNMT>L208F=L208V>L208K=L208R. Biochemical characterization of the two variants L208F and L208V exhibited similar Michaelis-Menten parameters for SAM and histamine while the enzymatic activity was reduced to 21% and 48%, respectively. A substantial loss of enzymatic activity and binding affinity for histamine was seen for the L208K and L208R variants. Similarly the thermal stability for the latter variants was reduced by 8 and 13°C, respectively. These findings demonstrate that position 208 is extremely sensitive to side chain variations and even conservative replacements affect enzymatic function. Molecular dynamics simulations showed that amino acid replacements in position 208 perturb the helical character and disrupt interactions with the adjacent β-strand, which is involved in the binding and correct positioning of histamine. This finding rationalizes the gradual loss of enzymatic activity observed in the L208 variants. Copyright © 2016 The Author(s). Published by Elsevier B.V. All rights reserved.

Inhibition of the TGF-β receptor I kinase promotes hematopoiesis in MDS

PubMed Central

Zhou, Li; Nguyen, Aaron N.; Sohal, Davendra; Ying Ma, Jing; Pahanish, Perry; Gundabolu, Krishna; Hayman, Josh; Chubak, Adam; Mo, Yongkai; Bhagat, Tushar D.; Das, Bhaskar; Kapoun, Ann M.; Navas, Tony A.; Parmar, Simrit; Kambhampati, Suman; Pellagatti, Andrea; Braunchweig, Ira; Zhang, Ying; Wickrema, Amittha; Medicherla, Satyanarayana; Boultwood, Jacqueline; Platanias, Leonidas C.; Higgins, Linda S.; List, Alan F.; Bitzer, Markus

2008-01-01

MDS is characterized by ineffective hematopoiesis that leads to peripheral cytopenias. Development of effective treatments has been impeded by limited insight into pathogenic pathways governing dysplastic growth of hematopoietic progenitors. We demonstrate that smad2, a downstream mediator of transforming growth factor–β (TGF-β) receptor I kinase (TBRI) activation, is constitutively activated in MDS bone marrow (BM) precursors and is overexpressed in gene expression profiles of MDS CD34+ cells, providing direct evidence of overactivation of TGF-β pathway in this disease. Suppression of the TGF-β signaling by lentiviral shRNA-mediated down-regulation of TBRI leads to in vitro enhancement of hematopoiesis in MDS progenitors. Pharmacologic inhibition of TBRI (alk5) kinase by a small molecule inhibitor, SD-208, inhibits smad2 activation in hematopoietic progenitors, suppresses TGF-β–mediated gene activation in BM stromal cells, and reverses TGF-β–mediated cell-cycle arrest in BM CD34+ cells. Furthermore, SD-208 treatment alleviates anemia and stimulates hematopoiesis in vivo in a novel murine model of bone marrow failure generated by constitutive hepatic expression of TGF-β1. Moreover, in vitro pharmacologic inhibition of TBRI kinase leads to enhancement of hematopoiesis in varied morphologic MDS subtypes. These data directly implicate TGF-β signaling in the pathobiology of ineffective hematopoiesis and identify TBRI as a potential therapeutic target in low-risk MDS. PMID:18474728

High-spin yrast structure of 204Hg from the decay of a four-hole, 22+ isomer

NASA Astrophysics Data System (ADS)

Wrzesiński, J.; Lane, G. J.; Maier, K. H.; Janssens, R. V. F.; Dracoulis, G. D.; Broda, R.; Byrne, A. P.; Carpenter, M. P.; Clark, R. M.; Cromaz, M.; Fornal, B.; Lauritsen, T.; Macchiavelli, A. O.; Rejmund, M.; Szpak, B.; Vetter, K.; Zhu, S.

2015-10-01

A high-spin isomer with τ >700 ns has been found in 204Hg , populated in reactions of 1360-MeV 208Pb and 330-MeV 48Ca beams with a thick 238U target and a 1450-MeV 208Pb beam on a thick 208Pb target. The observed γ -ray decay of the isomer has established the yrast states below it, including another isomer with τ =33 (3 ) ns. The experimental results are compared with shell-model calculations that include four holes in the configuration space between 132Sn and 208Pb . The available spectroscopic information, including transition strengths, total conversion, and angular correlation coefficients, together with the observed agreement with the calculations, allows spin, parity, and configuration assignments to be proposed for the experimental states. The τ >700 ns isomer is the 22+ state of maximum spin available from the alignment of the four valence holes with the configuration π h11/2 -2ν i13/2 -2 .

The macrocyclic peptide natural product CJ-15,208 is orally active and prevents reinstatement of extinguished cocaine-seeking behavior.

PubMed

Aldrich, Jane V; Senadheera, Sanjeewa N; Ross, Nicolette C; Ganno, Michelle L; Eans, Shainnel O; McLaughlin, Jay P

2013-03-22

The macrocyclic tetrapeptide natural product CJ-15,208 (cyclo[Phe-d-Pro-Phe-Trp]) exhibited both dose-dependent antinociception and kappa opioid receptor (KOR) antagonist activity after oral administration. CJ-15,208 antagonized a centrally administered KOR selective agonist, providing strong evidence it crosses the blood-brain barrier to reach KOR in the CNS. Orally administered CJ-15,208 also prevented both cocaine- and stress-induced reinstatement of extinguished cocaine-seeking behavior in the conditioned place preference assay in a time- and dose-dependent manner. Thus, CJ-15,208 is a promising lead compound with a unique activity profile for potential development, particularly as a therapeutic to prevent relapse to drug-seeking behavior in abstinent subjects.

8B + 208Pb Elastic Scattering at Coulomb Barrier Energies

NASA Astrophysics Data System (ADS)

La Commara, M.; Mazzocco, M.; Boiano, A.; Boiano, C.; Manea, C.; Parascandolo, C.; Pierroutsakou, D.; Signorini, C.; Strano, E.; Torresi, D.; Yamaguchi, H.; Kahl, D.; Di Meo, P.; Grebosz, J.; Imai, N.; Hirayama, Y.; Ishiyama, H.; Iwasa, N.; Jeong, S. C.; Jia, H. M.; Kim, Y. H.; Kimura, S.; Kubono, S.; Lin, C. J.; Miyatake, H.; Mukai, M.; Nakao, T.; Nicoletto, M.; Sakaguchi, Y.; Sánchez-Benítez, A. M.; Soramel, F.; Teranishi, T.; Wakabayashi, Y.; Watanabe, Y. X.; Yang, L.; Yang, Y. Y.

2018-02-01

The scattering process of weakly-bound nuclei at Coulomb barrier energies provides deep insights on the reaction dynamics induced by exotic nuclei. Within this framework, we measured for the first time the scattering process of the short-lived Radioactive Ion Beam (RIB) 8B (Sp = 0.1375 MeV) from a 208Pb target at 50 MeV beam energy. The 8B RIB was produced by means of the in-flight facility CRIB (RIKEN, Japan) with an average intensity on target of 10 kHz and a purity about 25%. Elastically scattering ions were detected in the angular range θc.m. = 10°-160° by means of the detector array EXPADES. A preliminary optical model analysis indicates a total reaction cross section of about 1 b, a value, once reduced, 2-3 times larger than those obtained for the reactions induced by the stable weakly-bound projectiles 6,7Li on a 208Pb target in the energy range around the Coulomb barrier.

8B + 208Pb Elastic Scattering at Coulomb Barrier Energies

NASA Astrophysics Data System (ADS)

La Commara, M.; Mazzocco, M.; Boiano, A.; Boiano, C.; Manea, C.; Parascandolo, C.; Pierroutsakou, D.; Signorini, C.; Strano, E.; Torresi, D.; Yamaguchi, H.; Kahl, D.; Di Meo, P.; Grebosz, J.; Imai, N.; Hirayama, Y.; Ishiyama, H.; Iwasa, N.; Jeong, S. C.; Jia, H. M.; Kim, Y. H.; Kimura, S.; Kubono, S.; Lin, C. J.; Miyatake, H.; Mukai, M.; Nakao, T.; Nicoletto, M.; Sakaguchi, Y.; Sánchez-Benítez, A. M.; Soramel, F.; Teranishi, T.; Wakabayashi, Y.; Watanabe, Y. X.; Yang, L.; Yang, Y. Y.

2017-11-01

The scattering process of weakly-bound nuclei at Coulomb barrier energies provides deep insights on the reaction dynamics induced by exotic nuclei. Within this framework, we measured for the first time the scattering process of the short-lived Radioactive Ion Beam (RIB) 8B (S p = 0.1375 MeV) from a 208Pb target at 50 MeV beam energy. The 8B RIB was produced by means of the in-flight facility CRIB (RIKEN, Japan) with an average intensity on target of 10 kHz and a purity about 25%. Elastically scattering ions were detected in the angular range θc.m. = 10°-160° by means of the detector array EXPADES. A preliminary optical model analysis indicates a total reaction cross section of about 1 b, a value, once reduced, 2-3 times larger than those obtained for the reactions induced by the stable weakly-bound projectiles 6,7Li on a 208Pb target in the energy range around the Coulomb barrier.

Targeting Energy Metabolic Pathways as Therapeutic Intervention for Breast Cancer

DTIC Science & Technology

2014-12-01

modulates the efficacy of curcumin and velcade against tumor cells. Autophagy. 2013, 9: 208-219. Cheng Y, Ren XC, Gowda P, Shan Y, Zhang L, Yuan YS...and modulates the efficacy of curcumin and velcade against tumor cells. Autophagy 2013; 9:208-19. 8. Parmer TG, Ward MD, Yurkow EJ, Vyas VH

The Macrocyclic Peptide Natural Product CJ-15,208 is Orally Active and Prevents Reinstatement of Extinguished Cocaine Seeking Behavior1

PubMed Central

Aldrich, Jane V.; Senadheera, Sanjeewa N.; Ross, Nicolette C.; Ganno, Michelle L.; Eans, Shainnel O.; McLaughlin, Jay P.

2013-01-01

The macrocyclic tetrapeptide natural product CJ-15,208 (cyclo[Phe-D-Pro-Phe-Trp]) exhibited both dose-dependent antinociception and kappa opioid receptor (KOR) antagonist activity after oral administration. CJ-15,208 antagonized a centrally administered KOR selective agonist, providing strong evidence it crosses the blood-brain barrier to reach KOR in the CNS. Orally administered CJ-15,208 also prevented both cocaine- and stress-induced reinstatement of extinguished cocaine seeking behavior in the conditioned place preference assay in a time- and dose-dependent manner. Thus, CJ-15,208 is a promising lead compound with a unique activity profile for potential development, particularly as a therapeutic to prevent relapse to drug seeking behavior in abstinent subjects. PMID:23327691

Discrimination of bullet types using analysis of lead isotopes deposited in gunshot entry wounds.

PubMed

Wunnapuk, Klintean; Minami, Takeshi; Durongkadech, Piya; Tohno, Setsuko; Ruangyuttikarn, Werawan; Moriwake, Yumi; Vichairat, Karnda; Sribanditmongkol, Pongruk; Tohno, Yoshiyuki

2009-01-01

In order to discriminate bullet types used in firearms, of which the victims died, the authors investigated lead isotope ratios in gunshot entry wounds from nine lead (unjacketed) bullets, 15 semi-jacketed bullets, and 14 full-jacketed bullets by inductively coupled plasma-mass spectrometry. It was found that the lead isotope ratio of 207/206 in gunshot entry wounds was the highest with lead bullets, and it decreased in order from full-jacketed to semi-jacketed bullets. Lead isotope ratios of 208/206 or 208/207 to 207/206 at the gunshot entry wound were able to discriminate semi-jacketed bullets from lead and full-jacketed ones, but it was difficult to discriminate between lead and full-jacketed bullets. However, a combination of element and lead isotope ratio analyses in gunshot entry wounds enabled discrimination between lead, semi-jacketed, and full-jacketed bullets.

Identification of alkaptonuria in the general population: a United Kingdom experience describing the challenges, possible solutions and persistent barriers.

PubMed

Ranganath, L; Taylor, A M; Shenkin, A; Fraser, W D; Jarvis, J; Gallagher, J A; Sireau, N

2011-06-01

Progress in research into rare diseases is challenging. This paper discusses strategies to identify individuals with the rare genetic disease alkaptonuria (AKU) within the general population. Strategies used included a questionnaire survey of general practitioners, a dedicated website and patient network contact, targeted family screening and medical conference targeting. Primary care physicians of the UK were targeted by a postal survey that involved mailing 11,151 UK GPs; the response rate was 18.2%. We have identified 75 patients in the UK with AKU by the following means: postal survey (23), targeted family screening (11), patient networks and the website (41). Targeting medical conferences (AKU, rare diseases, rheumatology, clinical biochemistry, orthopaedics, general practitioners) did not lead to new identification in the UK but helped identify overseas cases. We are now aware of 626 patients worldwide including newly identified non-UK people with AKU in the following areas: Slovakia (208), the rest of Europe (including Turkey) (79), North America (including USA and Canada) (110), and the rest of the world (154). A mechanism for identifying individuals with AKU in the general population-not just in the UK but worldwide-has been established. Knowledge of patients with AKU, both in the UK and outside, is often confined to establishing their location in a particular GP practice or association with a particular medical professional. Mere identification, however, does not always lead to full engagement for epidemiological research purposes or targeting treatment since further barriers exist.

Calculation of the Coulomb Fission Cross Sections for Pb-Pb and Bi-Pb Interactions at 158 A GeV

NASA Technical Reports Server (NTRS)

Poyser, William J.; Ahern, Sean C.; Norbury, John W.; Tripathi, R. K.

2002-01-01

The Weizsacker-Williams (WW) method of virtual quanta is used to make approximate cross section calculations for peripheral relativistic heavy-ion collisions. We calculated the Coulomb fission cross sections for projectile ions of Pb-208 and Bi-209 with energies of 158 A GeV interacting with a Pb-208 target. We also calculated the electromagnetic absorption cross section for Pb-208 ion interacting as described. For comparison we use both the full WW method and a standard approximate WW method. The approximate WW method in larger cross sections compared to the more accurate full WW method.

Radius anomaly in the diffraction model for heavy-ion elastic scattering

NASA Astrophysics Data System (ADS)

Pandey, L. N.; Mukherjee, S. N.

1984-04-01

The elastic scattering of heavy ions, 20Ne on 208Pb, 20Ne on 235U, 84Kr on 208Pb, and 84Kr on 232Th, is examined within the framework of Frahn's diffraction model. An analysis of the experiment using the "quarter point recipe" of the expected Fresnel cross sections yields a larger radius for 208Pb than the radii for 235U and 232Th. It is shown that inclusion of the nuclear deformation in the model removes the above anomaly in the radii, and the assumption of smooth cutoff of the angular momentum simultaneously leads to a better fit to elastic scattering data, compared to those obtained by the earlier workers on the assumption of sharp cutoff. [NUCLEAR REACTIONS Elastic scattering, 20Ne+208Pb (161.2 MeV), 20Ne+235U (175 MeV), 84Kr+208Pb (500 MeV), 84Kr+232Th (500 MeV), diffraction model, nuclear deformation.

Gottfried Sum Rule in QCD Nonsinglet Analysis of DIS Fixed-Target Data

NASA Astrophysics Data System (ADS)

Kotikov, A. V.; Krivokhizhin, V. G.; Shaikhatdenov, B. G.

2018-03-01

Deep-inelastic-scattering data from fixed-target experiments on the structure function F 2 were analyzed in the valence-quark approximation at the next-to-next-to-leading-order accuracy level in the strong-coupling constant. In this analysis, parton distributions were parametrized by employing information from the Gottfried sum rule. The strong-coupling constant was found to be α s ( M 2 Z) = 0.1180 ± 0.0020 (total expt. error), which is in perfect agreement with the world-averaged value from an updated Particle Data Group (PDG) report, α PDG s ( M 2 Z) = 0.1181 ± 0.0011. Also, the value of < x> u- d = 0.187 ± 0.021 found for the second moment of the difference in the u- and d-quark distributions complies very well with the most recent lattice result < x>LATTICE u- d = 0.208 ± 0.024.

Molecular Targeting of Prostate Cancer during Androgen Ablation: Inhibition of CHES1/FOXN3

DTIC Science & Technology

2012-05-01

histone deacetylase restores the DNA damage response in checkpoint- deficient strains of Saccharomyces cerevisiae. Mol Cell Biol 23, 4522-4531. 4. Ji...109,208,031 − 109,208,194 5 164 5.0666 C1orf62 56,874 548,058 TSS_upstream 9 chr16 65,080,679 − 65,080,894 5 216 4.9543 TK2 61,029 20,066 TES_downstream 10

Tracing fetal and childhood exposure to lead using isotope analysis of deciduous teeth

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shepherd, Thomas J.; British Geological Survey, Keyworth, Nottingham; Dirks, Wendy

We report progress in using the isotopic composition and concentration of Pb in the dentine and enamel of deciduous teeth to provide a high resolution time frame of exposure to Pb during fetal development and early childhood. Isotope measurements (total Pb and {sup 208}Pb/{sup 206}Pb, {sup 207}Pb/{sup 206}Pb ratios) were acquired by laser ablation inductively coupled mass spectrometry at contiguous 100 micron intervals across thin sections of the teeth; from the outer enamel surface to the pulp cavity. Teeth samples (n=10) were selected from two cohorts of children, aged 5–8 years, living in NE England. By integrating the isotope datamore » with histological analysis of the teeth, using the daily incremental lines in dentine, we were able to assign true estimated ages to each ablation point (first 2–3 years for molars, first 1–2 years for incisors+pre-natal growth). Significant differences were observed in the isotope composition and concentration of Pb between children, reflecting differences in the timing and sources of exposure during early childhood. Those born in 2000, after the withdrawal of leaded petrol in 1999, have the lowest dentine Pb levels (<0.2 µg Pb/g) with {sup 208}Pb/{sup 206}Pb (mean ±2σ: 2.126–2.079) {sup 208}Pb/{sup 206}Pb (mean ±2σ: 0.879–0.856) ratios that correlate very closely with modern day Western European industrial aerosols (PM{sub 10}, PM{sub 2.5}) suggesting that diffuse airborne pollution was probably the primary source and exposure pathway. Legacy lead, if present, is insignificant. For those born in 1997, dentine lead levels are typically higher (>0.4 µgPb/g) with {sup 208}Pb/{sup 206}Pb (mean ±2σ: 2.145–2.117) {sup 208}Pb/{sup 206}Pb (mean ±2σ: 0.898–0.882) ratios that can be modelled as a binary mix between industrial aerosols and leaded petrol emissions. Short duration, high intensity exposure events (1–2 months) were readily identified, together with evidence that dentine provides a good proxy for childhood changes in the isotope composition of blood Pb. Our pilot study confirms that laser ablation Pb isotope analysis of deciduous teeth, when carried out in conjunction with histological analysis, permits a reconstruction of the timing, duration and source of exposure to Pb during early childhood. With further development, this approach has the potential to study larger cohorts and appraise environments where the levels of exposure to Pb are much higher. - Highlights: • Reconstructing a high resolution chronology of early childhood exposure to lead. • Combined laser ablation lead isotope – histological analysis of children's teeth. • Using dentine to recover information on the intensity, duration and source of lead. • Importance of industrial airborne lead pollution in a post-leaded petrol era.« less

Roux-En-Y Gastric Bypass and Sleeve Gastrectomy Does Not Affect Food Preferences When Assessed by an Ad libitum Buffet Meal.

PubMed

Nielsen, Mette S; Christensen, Bodil J; Ritz, Christian; Rasmussen, Simone; Hansen, Thea T; Bredie, Wender L P; le Roux, Carel W; Sjödin, Anders; Schmidt, Julie B

2017-10-01

Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) lead to a reduction in energy intake. It is uncertain whether this reduction is simply due to eating smaller portions or if surgery changes food preferences towards less energy-dense food. Previous results rely on verbal reports, which may be prone to recall bias and underestimation of especially unhealthy foods. Using an ad libitum buffet meal targeting direct behavior, we investigated if RYGB and SG surgery leads to changes in food preferences. In addition, we assessed food preferences by a picture display test to explore differences between a method relying on verbal report and a method assessing direct behavior. Forty-one subjects (BMI 45.0 ± 6.8 kg/m 2 ) completed a visit pre- and 6 months post-RYGB (n = 31) and SG (n = 10). Mean BMI decreased with 11.7 ± 0.6 kg/m 2 and total energy intake at the buffet meal with 54% (4491 ± 208 kJ vs. 2083 ± 208 kJ, P < 0.001), respectively. However, relative energy intake from the following food categories: high-fat, low-fat, sweet, savory, high-fat-savory, high-fat-sweet, low-fat-savory, and low-fat-sweet, as well as energy density did not change following surgery (all P ≥ 0.18). In contrast, the picture display test showed that food from the low-fat-savory group was chosen more often post-surgery (34 ± 8% vs. 65 ± 9%, P = 0.02). The reduction in energy intake after RYGB and SG surgery and the subsequent weight loss seems to be primarily related to a reduction in portion sizes and not by changes in food preferences towards less energy-dense foods. These results underline the necessity of investigating eating behavior by targeting direct behavior.

Neutron density distributions of {sup 204,206,208}Pb deduced via proton elastic scattering at E{sub p}=295 MeV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zenihiro, J.; Sakaguchi, H.; Murakami, T.

Cross sections and analyzing powers for polarized proton elastic scattering from {sup 58}Ni, and {sup 204,206,208}Pb were measured at intermediate energy E{sub p}=295 MeV. An effective relativistic Love-Franey interaction is tuned to reproduce {sup 58}Ni scattering data within the framework of the relativistic impulse approximation. The neutron densities of the lead isotopes are deduced using model-independent sum-of-Gaussians distributions. Their error envelopes are estimated by a new {chi}{sup 2} criterion including uncertainties associated with the reaction model. The systematic behaviors of extracted error envelopes of the neutron density distributions in {sup 204,206,208}Pb are presented. The extracted neutron and proton density distributionmore » of {sup 208}Pb gives a neutron skin thickness of {Delta}r{sub np}=0.211{sub -0.063}{sup +0.054} fm.« less

An odyssey of environmental pollution: the rise, fall and remobilization of industrial lead in Australia

NASA Astrophysics Data System (ADS)

Taylor, M. P.; Kristensen, L.; Liqin, W.; Harvey, P. J.; Dong, C.; Rouillon, M.

2015-12-01

The use of lead in automobile gasoline resulted in more than 240,000 tonnes of lead being emitted to the Australian environment over its 70-year period of use starting in 1932. The consequences of the emissions and subsequent depositions have resulted in marked contamination of urban and peri-urban aerosols, soils, plants and humans. This paper charts these effects and examines the extent of recovery from one of the most pervasive and persistent environmental pollutants. Lead isotopic composition of Adelaide and Sydney aerosol filters show that air lead composition shifts from values that approximate Broken Hill type ores, the predominant lead source used in gasoline (1.04 206Pb/207Pb and 2.31 208Pb/207Pb), towards ratios that more closely match local uncontaminated soil and bedrock values (Adelaide ~1.19 206Pb/207Pb and ~2.50 208Pb/207Pb; Sydney ~1.15 206Pb/207Pb and 2.48 208Pb/207Pb). Proxy atmospheric measurements from historic wine, lichen and fungi samples extending over 120 years show how both concentration and composition values shifted in the middle to late 20th century to reflect petrol emissions and then recovered rapidly at the end of the century as leaded gasoline consumption declined. For example, lead in wine from South Australia fell from >100 μg/L in the 1960s and 1970s to < 5 μg/L in the 2010s due to the removal of the primary source of atmospheric lead - gasoline. However, measurement of contemporary surface soils, ash produced from wildfires and air filters demonstrate that the effect of depositions persists and industrial lead and other toxic metals (including arsenic, cadmium and nickel) are subject to frequent remobilization. Predicted increases in wildfires and the generation of lead, arsenic and cadmium toxic particulates warrants greater consideration of the risk for vulnerable populations and firefighters who are most exposed.

Lead-isotopic evidence for distinct source of granite and for distinct basement in the northern Appalachians, Maine.

USGS Publications Warehouse

Ayuso, R.A.

1986-01-01

Lead-isotopic compositions of feldspars in high-level Devonian granitic plutons across the northern Appalachians were measured. The presence of three fundamentally different sources of granites was indicated by three distinct lead-isotope groups. Plutons in the coastal lithotectonic block are the most radiogenic (206Pb/204Pb) 18.25-19.25; 207Pb/204Pb 15.59-15.67; 208Pb/204Pb 38.00-38.60); plutons in northern Maine are the least radiogenic (206Pb/204Pb 18.00-18.50; 207Pb/204Pb 15.51-15.55; 208Pb/204Pb 37.80-38.38). Intermediate lead-isotope values characterize the plutons in central Maine. All plutons show relatively radiogenic lead values for their ages and suggest the imprint of continental crustal sources, particularly in the coastal block. These plutons were formed in different crustal fragments in a continental environment, that were juxtaposed after emplacement of the granites.-L.C.H.

Neutron scattering from 208Pb at 30.4 and 40.0 MeV and isospin dependence of the nucleon optical potential

NASA Astrophysics Data System (ADS)

Devito, R. P.; Khoa, Dao T.; Austin, Sam M.; Berg, U. E. P.; Loc, Bui Minh

2012-02-01

Background: Analysis of data involving nuclei far from stability often requires the optical potential (OP) for neutron scattering. Because neutron data are seldom available, whereas proton scattering data are more abundant, it is useful to have estimates of the difference of the neutron and proton optical potentials. This information is contained in the isospin dependence of the nucleon OP. Here we attempt to provide it for the nucleon-208Pb system.Purpose: The goal of this paper is to obtain accurate n+208Pb scattering data and use it, together with existing p+208Pb and 208Pb(p,n)208BiIAS* data, to obtain an accurate estimate of the isospin dependence of the nucleon OP at energies in the 30-60-MeV range.Method: Cross sections for n+208Pb scattering were measured at 30.4 and 40.0 MeV, with a typical relative (normalization) accuracy of 2-4% (3%). An angular range of 15∘ to 130∘ was covered using the beam-swinger time-of-flight system at Michigan State University. These data were analyzed by a consistent optical-model study of the neutron data and of elastic p+208Pb scattering at 45 and 54 MeV. These results were combined with a coupled-channel analysis of the 208Pb(p,n) reaction at 45 MeV, exciting the 0+ isobaric analog state (IAS) in 208Bi.Results: The new data and analysis give an accurate estimate of the isospin impurity of the nucleon-208Pb OP at 30.4 MeV caused by the Coulomb correction to the proton OP. The corrections to the real proton OP given by the CH89 global systematics were found to be only a few percent, whereas for the imaginary potential it was greater than 20% at the nuclear surface. On the basis of the analysis of the measured elastic n+208Pb data at 40 MeV, a Coulomb correction of similar strength and shape was also predicted for the p+208Pb OP at energies around 54 MeV.Conclusions: Accurate neutron scattering data can be used in combination with proton scattering data and (p,n) charge exchange data leading to the IAS to obtain reliable estimates of the isospin impurity of the nucleon OP.

Accelerator driven neutron source design via beryllium target and 208Pb moderator for boron neutron capture therapy in alternative treatment strategy by Monte Carlo method.

PubMed

Khorshidi, Abdollah

2017-01-01

The reactor has increased its area of application into medicine especially boron neutron capture therapy (BNCT); however, accelerator-driven neutron sources can be used for therapy purposes. The present study aimed to discuss an alternative method in BNCT functions by a small cyclotron with low current protons based on Karaj cyclotron in Iran. An epithermal neutron spectrum generator was simulated with 30 MeV proton energy for BNCT purposes. A low current of 300 μA of the proton beam in spallation target concept via 9Be target was accomplished to model neutron spectrum using 208Pb moderator around the target. The graphite reflector and dual layer collimator were planned to prevent and collimate the neutrons produced from proton interactions. Neutron yield per proton, energy distribution, flux, and dose components in the simulated head phantom were estimated by MCNPX code. The neutron beam quality was investigated by diverse filters thicknesses. The maximum epithermal flux transpired using Fluental, Fe, Li, and Bi filters with thicknesses of 7.4, 3, 0.5, and 4 cm, respectively; as well as the epithermal to thermal neutron flux ratio was 161. Results demonstrated that the induced neutrons from a low energy and low current proton may be effective in tumor therapy using 208Pb moderator with average lethargy and also graphite reflector with low absorption cross section to keep the generated neutrons. Combination of spallation-based BNCT and proton therapy can be especially effective, if a high beam intensity cyclotron becomes available.

7 CFR 761.208 - Target participation rates for socially disadvantaged groups.

Code of Federal Regulations, 2010 CFR

2010-01-01

... for State and County levels annually. (3) When distributing loan funds in counties within Indian... in the county who are members of socially disadvantaged ethnic groups. (d) Women farmers. (1) The target participation rate for women farmers in each: (i) State is equal to the percent of farmers in the...

Lead Isotope Characterization of Petroleum Fuels in Taipei, Taiwan

PubMed Central

Yao, Pei-Hsuan; Shyu, Guey-Shin; Chang, Ying-Fang; Chou, Yu-Chen; Shen, Chuan-Chou; Chou, Chi-Su; Chang, Tsun-Kuo

2015-01-01

Leaded gasoline in Taiwan was gradually phased out from 1983 to 2000. However, it is unclear whether unleaded gasoline still contributes to atmospheric lead (Pb) exposure in urban areas. In this study, Pb isotopic compositions of unleaded gasolines, with octane numbers of 92, 95, 98, and diesel from two local suppliers in Taipei were determined by multi-collector inductively coupled plasma mass spectrometry with a two-sigma uncertainty of ± 0.02 %. Lead isotopic ratios of vehicle exhaust (208Pb/207Pb: 2.427, 206Pb/207Pb: 1.148, as estimated from petroleum fuels) overlap with the reported aerosol data. This agreement indicates that local unleaded petroleum fuels, containing 10–45 ng·Pb·g−1, are merely one contributor among various sources to urban aerosol Pb. Additionally, the distinction between the products of the two companies is statistically significant in their individual 208Pb/206Pb ratios (p-value < 0.001, t test). Lead isotopic characterization appears to be applicable as a “fingerprinting” tool for tracing the sources of Pb pollution. PMID:25918913

A regulatory sequence from the retinoid X receptor γ gene directs expression to horizontal cells and photoreceptors in the embryonic chicken retina.

PubMed

Blixt, Maria K E; Hallböök, Finn

2016-01-01

Combining techniques of episomal vector gene-specific Cre expression and genomic integration using the piggyBac transposon system enables studies of gene expression-specific cell lineage tracing in the chicken retina. In this work, we aimed to target the retinal horizontal cell progenitors. A 208 bp gene regulatory sequence from the chicken retinoid X receptor γ gene (RXRγ208) was used to drive Cre expression. RXRγ is expressed in progenitors and photoreceptors during development. The vector was combined with a piggyBac "donor" vector containing a floxed STOP sequence followed by enhanced green fluorescent protein (EGFP), as well as a piggyBac helper vector for efficient integration into the host cell genome. The vectors were introduced into the embryonic chicken retina with in ovo electroporation. Tissue electroporation targets specific developmental time points and in specific structures. Cells that drove Cre expression from the regulatory RXRγ208 sequence excised the floxed STOP-sequence and expressed GFP. The approach generated a stable lineage with robust expression of GFP in retinal cells that have activated transcription from the RXRγ208 sequence. Furthermore, GFP was expressed in cells that express horizontal or photoreceptor markers when electroporation was performed between developmental stages 22 and 28. Electroporation of a stage 12 optic cup gave multiple cell types in accordance with RXRγ gene expression in the early retina. In this study, we describe an easy, cost-effective, and time-efficient method for testing regulatory sequences in general. More specifically, our results open up the possibility for further studies of the RXRγ-gene regulatory network governing the formation of photoreceptor and horizontal cells. In addition, the method presents approaches to target the expression of effector genes, such as regulators of cell fate or cell cycle progression, to these cells and their progenitor.

Tracing changes in atmospheric sources of lead contamination using lead isotopic compositions in Australian red wine.

PubMed

Kristensen, Louise Jane; Taylor, Mark Patrick; Evans, Andrew James

2016-07-01

Air quality data detailing changes to atmospheric composition from Australia's leaded petrol consumption is spatially and temporally limited. In order to address this data gap, wine was investigated as a potential proxy for atmospheric lead conditions. Wine spanning sixty years was collected from two wine regions proximal to the South Australian capital city, Adelaide, and analysed for lead concentration and lead and strontium isotopic composition for source apportionment. Maximum wine lead concentrations (328 μg/L) occur prior to the lead-in-air monitoring in South Australia in the later 1970s. Wine lead concentrations mirror available lead-in-air measurements and show a declining trend reflecting parallel reductions in leaded petrol emissions. Lead from petrol dominated the lead in wine ((206)Pb/(207)Pb: 1.086; (208)Pb/(207)Pb: 2.360) until the introduction of unleaded petrol, which resulted in a shift in the wine lead isotopic composition closer to vineyard soil ((206)Pb/(207)Pb: 1.137; (208)Pb/(207)Pb: 2.421). Current mining activities or vinification processes appear to have no impact with recent wine samples containing less than 4 μg/L of lead. This study demonstrates wine can be used to chronicle changes in environmental lead emissions and is an effective proxy for atmospherically sourced depositions of lead in the absence of air quality data. Copyright © 2016 Elsevier Ltd. All rights reserved.

7 CFR 761.208 - Target participation rates for socially disadvantaged groups.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Indian reservations, the Agency will allocate the funds on a reservation-wide basis. (4) The Agency... groups. (d) Women farmers. (1) The target participation rate for women farmers in each: (i) State is equal to the percent of farmers in the State who are women. (ii) County is equal to the percent of...

7 CFR 761.208 - Target participation rates for socially disadvantaged groups.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Indian reservations, the Agency will allocate the funds on a reservation-wide basis. (4) The Agency... groups. (d) Women farmers. (1) The target participation rate for women farmers in each: (i) State is equal to the percent of farmers in the State who are women. (ii) County is equal to the percent of...

7 CFR 761.208 - Target participation rates for socially disadvantaged groups.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Indian reservations, the Agency will allocate the funds on a reservation-wide basis. (4) The Agency... groups. (d) Women farmers. (1) The target participation rate for women farmers in each: (i) State is equal to the percent of farmers in the State who are women. (ii) County is equal to the percent of...

Investigation of off-site airborne transport of lead from a superfund removal action site using lead isotope ratios and concentrations

USGS Publications Warehouse

Pribil, Michael J.; Maddaloni, Mark A.; Staiger, Kimberly; Wilson, Eric; Magriples, Nick; Ali, Mustafa; Santella, Dennis

2014-01-01

Lead (Pb) concentration and Pb isotopic composition of surface and subsurface soil samples were used to investigate the potential for off-site air transport of Pb from a former white Pb processing facility to neighboring residential homes in a six block area on Staten Island, NY. Surface and subsurface soil samples collected on the Jewett White Pb site were found to range from 1.122 to 1.138 for 206Pb/207Pb and 2.393 to 2.411 for 208Pb/207Pb. The off-site surface soil samples collected from residential backyards, train trestle, near site grass patches and background areas varied from 1.144 to 1.196 for 206Pb/207Pb and 2.427 to 2.464 for 208Pb/207Pb. Two soil samples collected along Richmond Terrace, where Jewett site soils accumulated after major rain events, varied from 1.136 to 1.147 for 206Pb/207Pb and 2.407 to 2.419 for 208Pb/207Pb. Lead concentration for on-site surface soil samples ranged from 450 to 8000 ug/g, on-site subsurface soil samples ranged from 90,000 to 240,000 ug/g and off-site samples varied from 380 to 3500 ug/g. Lead concentration and isotopic composition for the Staten Island off-site samples were similar to previously published data for other northeastern US cities and reflect re-suspension and re-mobilization of local accumulated Pb. The considerable differences in both the Pb isotopic composition and Pb concentration of on-site and off-site samples resulted in the ability to geochemically trace the transport of particulate Pb. Data in this study indicate minimal off-site surface transport of Pb from the Jewett site into the neighboring residential area.

The verbal facilitation effect: re-reading person descriptions as a system variable to improve identification performance.

PubMed

Sporer, Siegfried L; Kaminski, Kristina S; Davids, Maike C; McQuiston, Dawn

2016-11-01

When witnesses report a crime, police usually ask for a description of the perpetrator. Several studies suggested that verbalising faces leads to a detriment in identification performance (verbal overshadowing effect [VOE]) but the effect has been difficult to replicate. Here, we sought to reverse the VOE by inducing context reinstatement as a system variable through re-reading one's own description before an identification task. Participants (N = 208) watched a video film and were then dismissed (control group), only described the perpetrator, or described and later re-read their own descriptions before identification in either target-present or target-absent lineups after a 2-day or a 5-week delay. Identification accuracy was significantly higher after re-reading (85.0%) than in the no description control group (62.5%) irrespective of target presence. Data were internally replicated using a second target and corroborated by several small meta-analyses. Identification accuracy was related to description quality. Moreover, there was a tendency towards a verbal facilitation effect (VFE) rather than a VOE. Receiver operating characteristic (ROC) curve analyses confirm that our findings are not due to a shift in response bias but truly reflect improvement of recognition performance. Differences in the ecological validity of study paradigms are discussed.

Metal enrichment and lead isotope analysis for source apportionment in the urban dust and rural surface soil.

PubMed

Yu, Yang; Li, Yingxia; Li, Ben; Shen, Zhenyao; Stenstrom, Michael K

2016-09-01

To understand the metal accumulation in the environment and identify its sources, 29 different metal contents and lead (Pb) isotope ratios were determined for 40 urban dust samples, 36 surface soil samples, and one river sediment sample collected in the municipality of Beijing, China. Results showed that cadmium, copper (Cu), mercury, Pb, antimony (Sb), and zinc demonstrated to be the typical urban contaminants and mostly influenced by the adjacent human activities with higher content to background ratios and SD values. Among the 29 metal elements investigated, Cu and Sb were found to be the most distinct elements that were highly affected by the developing level and congestion status of the cities with much higher contents in dust in more developed and congested cities. There was a relatively wider range of Pb isotope ratios of country surface soil than those of urban dust. The results of source identification based on Pb isotope ratios showed that coal combustion was the first largest Pb source and vehicle exhaust was the second largest source. The sum of them accounted for 74.6% mass proportion of overall Pb pollution on average. The surface soil sample collected at an iron mine had the highest (204)Pb/(206)Pb, (207)Pb/(206)Pb, and (208)Pb/(206)Pb ratios indicating ore had much higher ratios than other sources. The fine particle subsamples had higher (204)Pb/(206)Pb, (207)Pb/(206)Pb, and (208)Pb/(206)Pb ratios than the coarse particle subsamples indicating more anthropogenic sources of coal combustion and vehicle exhaust for fine particles and more background influence for coarse particles. These results help with pinpointing the major Pb sources and applying suitable measures for the target sources. Copyright © 2016 Elsevier Ltd. All rights reserved.

Void effect analysis of Pb-208 of fast reactors with modified CANDLE burn-up scheme

DOE Office of Scientific and Technical Information (OSTI.GOV)

Widiawati, Nina, E-mail: nina-widiawati28@yahoo.com; Su’ud, Zaki, E-mail: szaki@fi.itb.ac.id

Void effect analysis of Pb-208 as coolant of fast reactors with modified candle burn-up scheme has been conducted. Lead cooled fast reactor (LFR) is one of the fourth-generation reactor designs. The reactor is designed with a thermal power output of 500 MWt. Modified CANDLE burn-up scheme allows the reactor to have long life operation by supplying only natural uranium as fuel cycle input. This scheme introducing discrete region, the fuel is initially put in region 1, after one cycle of 10 years of burn up it is shifted to region 2 and region 1 is filled by fresh natural uraniummore » fuel. The reactor is designed for 100 years with 10 regions arranged axially. The results of neutronic calculation showed that the void coefficients ranged from −0.6695443 % at BOC to −0.5273626 % at EOC for 500 MWt reactor. The void coefficients of Pb-208 more negative than Pb-nat. The results showed that the reactors with Pb-208 coolant have better level of safety than Pb-nat.« less

12 CFR Appendix D-1 to Part 208 - Interagency Guidelines Establishing Standards for Safety and Soundness

Code of Federal Regulations, 2014 CFR

2014-01-01

... benefits and any compensatory arrangement that could lead to material financial loss to an institution... or that could lead to material financial loss to the institution. III. Prohibition on Compensation...-cash benefits provided to the individual; 2. The compensation history of the individual and other...

12 CFR Appendix D-1 to Part 208 - Interagency Guidelines Establishing Standards for Safety and Soundness

Code of Federal Regulations, 2012 CFR

2012-01-01

... benefits and any compensatory arrangement that could lead to material financial loss to an institution... or that could lead to material financial loss to the institution. III. Prohibition on Compensation...-cash benefits provided to the individual; 2. The compensation history of the individual and other...

12 CFR Appendix D-1 to Part 208 - Interagency Guidelines Establishing Standards for Safety and Soundness

Code of Federal Regulations, 2013 CFR

2013-01-01

... benefits and any compensatory arrangement that could lead to material financial loss to an institution... or that could lead to material financial loss to the institution. III. Prohibition on Compensation...-cash benefits provided to the individual; 2. The compensation history of the individual and other...

Combining lead isotopes and cluster analysis to distinguish the Guarani and Serra Geral Aquifer Systems and contaminated waters in a highly industrialized area in Southern Brazil.

PubMed

Kuhn, Isadora Aumond; Roisenberg, Ari

2017-10-01

The Rio dos Sinos Watershed area is located at the Middle-West region of the Rio Grande do Sul State, Southern Brazil, along thirty two municipalities and affecting 1.5 million inhabitants and many important industrial centers. Three main aquifers are recognized in the study area: the unconfined-fractured Serra Geral Aquifer System, the porous Guarani Aquifer System, and the Permian Aquitard. This study aims to understand groundwater, surface water and human activity interactions in the Rio dos Sinos Watershed, evaluating the application of stable lead isotopic ratios analyzed for this propose. Thirty six groundwater samples, 8 surface water samples and 5 liquid effluents of tanneries and landfills samples were measured using a Thermal Ionization Mass Spectrometer Thermo-Finnigan and a Neptune Multi-Collector Inductively Coupled Plasma Mass Spectrometer. Groundwater isotopic ratios have a wider range compared to the surface water, with less radiogenic averages 208 Pb/ 204 Pb = 38.1837 vs 38.4050 (standard deviation = 0.2921 vs 0.1343) and 206 Pb/ 204 Pb = 18.2947 vs 18.4766 (standard deviation = 0.2215 vs 0.1059), respectively. Industrial liquid effluents (tanneries and industrial landfill) have averages 208 Pb/ 204 Pb = 38.1956 and 206 Pb/ 204 Pb = 18.3169, distinct from effluent samples of domestic sanitary landfill (averages 208 Pb/ 204 Pb = 38.2353 and 206 Pb/ 204 Pb = 18.6607). Hierarchical cluster analysis led to distinguish six groups of groundwater, representing the three aquifers that occur in the area, two clusters suggesting groundwater mixtures and one demonstrating a highly contaminated groundwater. By analyzing the cluster results and wells' stratigraphic profiles it was possible to distinguish the different aquifers in the area. The Serra Geral Aquifer System has 206 Pb/ 204 Pb ratios between 18.4718 and 18.7089; 207 Pb/ 204 Pb between 15.6692 and 15.6777; 208 Pb/ 204 Pb between 38.6826 and 38.7616; 207 Pb/ 206 Pb between 0.8372 and 0.8623; 208 Pb/ 206 Pb between 2.0671 and 2.0964 and the Guarani Aquifer System has a wider range ( 208 Pb/ 204 Pb ranged from 37.9393 to 38.1279 and 206 Pb/ 204 Pb ranged from 18.0892 to 18.3217). Water mixing of these two aquifer systems is reflected by transitional results. The results confirm that the hierarchical cluster analysis of lead isotopes is a useful tool to discriminate different aquifer conditions, reflecting mostly the influence of the natural lead isotopic composition of the aquifers instead of the anthropogenic activities (urban and industrial), except when the groundwater is highly contaminated by human activity. Copyright © 2017 Elsevier Ltd. All rights reserved.

Breakup and fusion cross sections of the 6Li nucleus with targets of mass A = 58, 144 and 208

NASA Astrophysics Data System (ADS)

Mukeru, B.; Rampho, G. J.; Lekala, M. L.

2018-04-01

We use the continuum discretized coupled channels method to investigate the effects of continuum-continuum coupling on the breakup and fusion cross sections of the weakly bound 6Li nucleus with the 58Ni, 144Sm and 208Pb nuclear targets. The cross sections were analyzed at incident energies E cm below, close to and above the Coulomb barrier V B. We found that for the medium and heavy targets, the breakup cross sections are enhanced at energies below the Coulomb barrier (E cm/V B ≤ 0.8) owing to these couplings. For the lighter target, relatively small enhancement of the breakup cross sections appear at energies well below the barrier (E cm/V B ≤ 0.6). At energies E cm/V B > 0.8 for medium and heavy targets, and E cm/V B > 0.6 for the light target, the continuum-continuum couplings substantially suppress the breakup cross sections. On the other hand, the fusion cross sections are enhanced at energies E cm/V B < 1.4, E cm/V B < 1.2 and E cm/V B < 0.8 for the light, medium and heavy target, respectively. The enhancement decreases as the target mass increases. Above the indicated respective energies, these couplings suppress the fusion cross sections. We also compared the breakup and fusion cross sections, and found that below the barrier, the breakup cross sections are more dominant regardless of whether continuum-continuum couplings are included.

Flux rates of atmospheric lead pollution within soils of a small catchment in northern Sweden and their implications for future stream water quality.

PubMed

Klaminder, Jonatan; Bindler, Richard; Laudon, Hjalmar; Bishop, Kevin; Emteryd, Ove; Renberg, Ingemar

2006-08-01

It is not well-known how the accumulated pool of atmospheric lead pollution in the boreal forest soil will affect the groundwater and surface water chemistry in the future as this lead migrates through the soil profile. This study uses stable lead isotopes (206Pb/207Pb and 208Pb/ 207Pb ratios) to trace the transport of atmospheric lead pollution within the soil of a small catchment and predict future lead level changes in a stream draining the catchment. Low 206Pb/207Pb and 208Pb/207Pb ratios for the lead in the soil water (1.16 +/- 0.02; 2.43 +/- 0.03) and streamwater (1.18 +/- 0.03; 2.42 +/- 0.03) in comparison to that of the mineral soil (>1.4; >2.5) suggest that atmospheric pollution contributes by about 90% (65-100%) to the lead pool found in these matrixes. Calculated transport rates of atmospheric lead along a soil transect indicate that the mean residence time of lead in organic and mineral soil layers is at a centennial to millennial time scale. A maximum release of the present pool of lead pollution in the soil to the stream is predicted to occur within 200-800 years. Even though the uncertainty of the prediction is large, it emphasizes the magnitude of the time lag between the accumulation of atmospheric lead pollution in soils and the subsequent response in streamwater quality.

One-group fission cross sections for plutonium and minor actinides inserted in calculated neutron spectra of fast reactor cooled with lead-208 or lead-bismuth eutectic

DOE Office of Scientific and Technical Information (OSTI.GOV)

Khorasanov, G. L.; Blokhin, A. I.

The paper is dedicated to one-group fission cross sections of Pu and MA in LFRs spectra with the aim to increase these values by choosing a coolant which hardens neutron spectra. It is shown that replacement of coolant from Pb-Bi with Pb-208 in the fast reactor RBEC-M, designed in Russia, leads to increasing the core mean neutron energy. As concerns fuel Pu isotopes, their one-group fission cross sections become slightly changed, while more dramatically Am-241 one-group fission cross section is changed. Another situation occurs in the lateral blanket containing small quantities of minor actinides. It is shown that as amore » result of lateral blanket mean neutron energy hardening the one-group fission cross sections of Np-237, Am-241 and Am-243 increases up to 8-11%. This result allows reducing the time of minor actinides burning in FRs. (authors)« less

Containing arsenic-enriched groundwater tracing lead isotopic compositions of common arsenical pesticides in a coastal Maine watershed

USGS Publications Warehouse

Ayuso, Robert A.; Foley, Nora K.; Robinson, Glipin R.; Colvin, A.S.; Lipfert, G.; Reeve, A.S.

2006-01-01

Arsenical pesticides and herbicides were extensively used on apple, blueberry, and potato crops in New England during the first half of the twentieth century. Lead arsenate was the most heavily used arsenical pesticide until it was officially banned. Lead arsenate, calcium arsenate, and sodium arsenate have similar Pb isotope compositions: 208Pb207Pb = 2.3839-2.4722, and 206Pb207Pb = 1.1035-1.2010. Other arsenical pesticides such as copper acetoarsenite (Paris green), methyl arsonic acid and methane arsonic acid, as well as arsanilic acid are widely variable in isotope composition. Although a complete understanding of the effects of historical use of arsenical pesticides is not available, initial studies indicate that arsenic and lead concentrations in stream sediments in New England are higher in agricultural areas that intensely used arsenical pesticides than in other areas. The Pb isotope compositions of pesticides partially overlap values of stream sediments from areas with the most extensive agricultural use. The lingering effects of arsenical pesticide use were tested in a detailed geochemical and isotopic study of soil profiles from a watershed containing arsenic-enriched ground water in coastal Maine. Acid-leach compositions of the soils represent lead adsorbed to mineral surfaces or held in soluble minerals (Fe- and Mn-hydroxides, carbonate, and some micaceous minerals), whereas residue compositions likely reflect bedrock compositions. The soil profiles contain labile Pb (acid-leach) showing a moderate range in 206Pb 207Pb (1.1870-1.2069), and 208Pb207Pb (2.4519-2.4876). Isotope values vary as a function of depth: the lowest Pb isotope ratios (e.g.,208Pb206Pb) representing labile lead are in the uppermost soil horizons. Lead contents decrease with depth in the soil profiles. Arsenic contents show no clear trend with depth. A multi-component mixing scheme that included lead from the local parent rock (Penobscot Formation), lead derived from combustion of fossil fuels, and possibly lead from other anthropogenic sources (e.g., pesticides), could account for Pb isotope variations in the soil profiles. In agricultural regions, our preliminary data show that the extensive use of arsenical pesticides and herbicides can be a significant anthropogenic source of arsenic and lead to stream sediments and soils.

Lead contamination in cocoa and cocoa products: isotopic evidence of global contamination.

PubMed

Rankin, Charley W; Nriagu, Jerome O; Aggarwal, Jugdeep K; Arowolo, Toyin A; Adebayo, Kola; Flegal, A Russell

2005-10-01

In this article we present lead concentrations and isotopic compositions from analyses of cocoa beans, their shells, and soils from six Nigerian cocoa farms, and analyses of manufactured cocoa and chocolate products. The average lead concentration of cocoa beans was

Lead Contamination in Cocoa and Cocoa Products: Isotopic Evidence of Global Contamination

PubMed Central

Rankin, Charley W.; Nriagu, Jerome O.; Aggarwal, Jugdeep K.; Arowolo, Toyin A.; Adebayo, Kola; Flegal, A. Russell

2005-01-01

In this article we present lead concentrations and isotopic compositions from analyses of cocoa beans, their shells, and soils from six Nigerian cocoa farms, and analyses of manufactured cocoa and chocolate products. The average lead concentration of cocoa beans was ≤ 0.5 ng/g, which is one of the lowest reported values for a natural food. In contrast, lead concentrations of manufactured cocoa and chocolate products were as high as 230 and 70 ng/g, respectively, which are consistent with market-basket surveys that have repeatedly listed lead concentrations in chocolate products among the highest reported for all foods. One source of contamination of the finished products is tentatively attributed to atmospheric emissions of leaded gasoline, which is still being used in Nigeria. Because of the high capacity of cocoa bean shells to adsorb lead, contamination from leaded gasoline emissions may occur during the fermentation and sun-drying of unshelled beans at cocoa farms. This mechanism is supported by similarities in lead isotopic compositions of cocoa bean shells from the different farms (206Pb/207Pb = 1.1548–1.1581; 208Pb/207Pb = 2.4344–2.4394) with those of finished cocoa products (206Pb/207Pb = 1.1475–1.1977; 208Pb/207Pb = 2.4234–2.4673). However, the much higher lead concentrations and larger variability in lead isotopic composition of finished cocoa products, which falls within the global range of industrial lead aerosols, indicate that most contamination occurs during shipping and/or processing of the cocoa beans and the manufacture of cocoa and chocolate products. PMID:16203244

Fusion-fission and quasifission in the reactions with heavy ions leading to the formation of Hs

NASA Astrophysics Data System (ADS)

Itkis, I. M.; Itkis, M. G.; Knyazheva, G. N.; Kozulin, E. M.

2012-10-01

Mass and energy distributions of binary reaction products obtained in the reactions 22Ne+249Cf,26Mg+248Cm,36S+238U and 58Fe+208Pb leading to Hs isotopes have been measured. At energies below the Coulomb barrier the bimodal fission of Hs*, formed in the reaction 26Mg+248Cm, is observed. In the reaction 36S+238U the considerable part of the symmetric fragments arises from the quasifission process. At energies above the Coulomb barrier the symmetric fragments originate mainly from fusion-fission process for both reactions with Mg and S ions. In the case of the 58Fe+208Pb reaction the quasifission process dominates at all measured energies. The pre- and post-scission neutron multiplicities as a function of the fragment mass have been obtained for the reactions studied.

Inhibition of transforming growth factor-β attenuates brain injury and neurological deficits in a rat model of germinal matrix hemorrhage.

PubMed

Manaenko, Anatol; Lekic, Tim; Barnhart, Margaret; Hartman, Richard; Zhang, John H

2014-03-01

Transforming growth factor-β (TGF-β) overproduction and activation of the TGF-β pathway are associated with the development of brain injury following germinal matrix hemorrhage (GMH) in premature infants. We examined the effects of GMH on the level of TGF-β1 in a novel rat collagenase-induced GMH model and determined the effect of inhibition of the TGF receptor I. In total, 92 seven-day old (P7) rats were used. Time-dependent effects of GMH on the level of TGF-β1 and TGF receptor I were evaluated by Western blot. A TGF receptor I inhibitor (SD208) was administered daily for 3 days, starting either 1 hour or 3 days after GMH induction. The effects of GMH and SD208 on the TGF-β pathway were evaluated by Western blot at day 3. The effects of GMH and SD208 on cognitive and motor function were also assessed. The effects of TGF receptor I inhibition by SD208 on GMH-induced brain injury and underlying molecular pathways were investigated by Western blot, immunofluorescence, and morphology studies 24 days after GMH. GMH induced significant delay in development, caused impairment in both cognitive and motor functions, and resulted in brain atrophy in rat subjects. GMH also caused deposition of both vitronectin (an extracellular matrix protein) and glial fibrillary acidic protein in perilesion areas, associated with development of hydrocephalus. SD208 ameliorated GMH-induced developmental delay, improved cognitive and motor functions, and attenuated body weight loss. SD208 also decreased vitronectin and glial fibrillary acidic protein deposition and decreased GMH-induced brain injury. Increased level of TGF-β1 and activation of the TGF-β pathway associate with the development of brain injury after GMH. SD208 inhibits GMH-induced activation of the TGF-β pathway and leads to an improved developmental profile, partial recovery of cognitive and motor functions, and attenuation of GMH-induced brain atrophy and hydrocephalus.

Identifying sources of Pb pollution in urban soils by means of MC-ICP-MS and TOF-SIMS.

PubMed

Rodríguez-Seijo, Andrés; Arenas-Lago, Daniel; Andrade, María Luisa; Vega, Flora A

2015-05-01

Lead pollution was evaluated in 17 urban soils from parks and gardens in the city of Vigo (NW Spain). The Pb isotope ratios ((207)Pb/(206)Pb, (208)Pb/(204)Pb, (206)Pb/(204)Pb and (208)Pb/(206)Pb) were determined after being measured by MC-ICP-MS. The association of the isotopes ((204)Pb, (206)Pb, (207)Pb and (208)Pb) with the different components of the soil was studied using TOF-SIMS. The isotopic ranges obtained for the samples were between 1.116 and 1.203 ((206)Pb/(207)Pb), 2.044-2.143 ((208)Pb/(206)Pb), 37.206-38.608 ((208)Pb/(204)Pb), 15.5482-15.6569 ((207)Pb/(204)Pb) and 17.357-18.826 ((206)Pb/(204)Pb). The application of the three-end-member model indicates that the Pb derived from petrol is the main source of Pb in the soils (43.51% on average), followed by natural or geogenic Pb (39.12%) and industrial emissions (17.37%). The emissions derived from coal combustion do not appear to influence the content of Pb in the soil. TOF-SIMS images show that the Pb mainly interacts with organic matter. This technique contributes to the understanding of the association of anthropogenic Pb with the components of the soil, as well as the particle size of these associations, thus allowing the possible sources of Pb to be identified.

Determined Initial lead for South Of Isua (SOI) terrain suggests a single homogeneous source for it and possibly other archaean rocks

NASA Astrophysics Data System (ADS)

Tera, F.

2011-12-01

A Thorogenic-Uranogenic Lead Isotope Plane (TULIP), which entails plotting 206/208 (or its reverse) vs 207/208 (or its reverse), was applied to the Pb data on South of Isua (SOI) by Kamber et al., (1). When the data on 20 samples of these rocks and feldspars are plotted in pairs (each pair is a rock and its feldspar) on TULIP, they fall on 10 mixing lines that converge on a single spot (Fig. 1). This is the end member initial lead (EMIL). The 206/208 & 207/208 so determined are 0.3675 and 0.43525, respectively. From these values one calculates 207/206 = 1.1843 ± 0.0007, for EMIL. This pattern requires either: A) each pair has a singular kappa, K = 232Th/238U, different from others, or B) a pair's in situ decay Pb was homogenized in recent times. On 204/206 vs 207/206 diagram, the whole rocks of SOI define a 3.776 Ga isochron (2). From this and EMIL's 207/206, one obtains: 206/204 = 10.977, 207/204 = 12.974; and 208/204 = 29.756. This singularity of initial Pb contrasts with a deduced variability by the original authors (1). EMIL's radiogenic *(207/206) = 1.6220, gives a single-stage age = 5.9 Ga, indicating inapplicability of its evolution in one stage. Also, the μ calculated from 238U-206Pb for the single stage is different from that inferred from 235U-207Pb, confirming disqualification of this scenario. Reconciliation of the two decay schemes necessitates assumption of EMIL evolution in a minimum of two stages. Starting at 4.563 Ga, five scenarios were assumed: First stage ends and second starts at 4.55, 4.54, 4.53, 4.52 or 4.51 Ga. Second stages end at 3.776 Ga. The calculated μ1 for the first stage are 106, 59.5, 44.6, 36.3 and 30.9 respectively. For μ2 the change is limited, from 5.45 to 5.28. Only an average calculated K for both stages is possible. For the five outlined scenarios it ranges from 1.118 to 1.111. Earlier, Tera (3) observed that initial Pb of the oldest terrestrial reservoir requires evolution in two stages. There too μ1 >> μ2. Data on other rocks from Isua Greenstone Belt (1) and Amîtsoq gneiss (4) fall inside the TULIP triangle of SOI, suggesting potential derivation of these Archaean rocks from the same homogeneous source.

Compaction at the longitudinal construction joint in asphalt pavements (KYSPR-00-208)

DOT National Transportation Integrated Search

2002-05-01

Poor compaction practices at longitudinal construction joints in hot-mix asphalt (HMA) pavements lead to premature pavement failure. The hypothesis is that poorly constructed or compacted HMA joints tend to be more permeable and allow water to enter ...

Racial and Socioeconomic Disparities in Nutrition Behaviors: Targeted Interventions Needed

ERIC Educational Resources Information Center

Fahlman, Mariane M.; McCaughtry, Nate; Martin, Jeffrey; Shen, Bo

2010-01-01

Objective: To compare dietary knowledge, behaviors and self-efficacy of black middle school students of low socioeconomic status with their white counterparts of higher socioeconomic status. Design: Cross-sectional, school-based survey. Setting: Large metropolitan area in the United States. Participants: Middle school students (1,208 of low…

Targeting Energy Metabolic Pathways as Therapeutic Intervention for Breast Cancer

DTIC Science & Technology

2013-10-01

known as the Warburg effect. Glycolytic cancer cells are believed to be resistant to anticancer treatment and to induction of apoptosis mediated...autophagy and apoptosis by EEF2K controls cellular fate and modulates the efficacy of curcumin and velcade against tumor cells. Autophagy. 2013, 9: 208-219

Identification of TMEM208 and PQLC2 as reference genes for normalizing mRNA expression in colorectal cancer treated with aspirin

PubMed Central

Zhu, Yuanyuan; Yang, Chao; Weng, Mingjiao; Zhang, Yan; Yang, Chunhui; Jin, Yinji; Yang, Weiwei; He, Yan; Wu, Yiqi; Zhang, Yuhua; Wang, Guangyu; RajkumarEzakiel Redpath, Riju James; Zhang, Lei; Jin, Xiaoming; Liu, Ying; Sun, Yuchun; Ning, Ning; Qiao, Yu; Zhang, Fengmin; Li, Zhiwei; Wang, Tianzhen; Zhang, Yanqiao; Li, Xiaobo

2017-01-01

Numerous evidences indicate that aspirin usage causes a significant reduction in colorectal cancer. However, the molecular mechanisms about aspirin preventing colon cancer are largely unknown. Quantitative reverse transcription polymerase chain reaction (qRT-PCR) is a most frequently used method to identify the target molecules regulated by certain compound. However, this method needs stable internal reference genes to analyze the expression change of the targets. In this study, the transcriptional stabilities of several traditional reference genes were evaluated in colon cancer cells treated with aspirin, and also, the suitable internal reference genes were screened by using a microarray and were further identified by using the geNorm and NormFinder softwares, and then were validated in more cell lines and xenografts. We have showed that three traditional internal reference genes, β-actin, GAPDH and α-tubulin, are not suitable for studying gene transcription in colon cancer cells treated with aspirin, and we have identified and validated TMEM208 and PQLC2 as the ideal internal reference genes for detecting the molecular targets of aspirin in colon cancer in vitro and in vivo. This study reveals stable internal reference genes for studying the target genes of aspirin in colon cancer, which will contribute to identify the molecular mechanism behind aspirin preventing colon cancer. PMID:28184026

Identification of TMEM208 and PQLC2 as reference genes for normalizing mRNA expression in colorectal cancer treated with aspirin.

PubMed

Zhu, Yuanyuan; Yang, Chao; Weng, Mingjiao; Zhang, Yan; Yang, Chunhui; Jin, Yinji; Yang, Weiwei; He, Yan; Wu, Yiqi; Zhang, Yuhua; Wang, Guangyu; RajkumarEzakiel Redpath, Riju James; Zhang, Lei; Jin, Xiaoming; Liu, Ying; Sun, Yuchun; Ning, Ning; Qiao, Yu; Zhang, Fengmin; Li, Zhiwei; Wang, Tianzhen; Zhang, Yanqiao; Li, Xiaobo

2017-04-04

Numerous evidences indicate that aspirin usage causes a significant reduction in colorectal cancer. However, the molecular mechanisms about aspirin preventing colon cancer are largely unknown. Quantitative reverse transcription polymerase chain reaction (qRT-PCR) is a most frequently used method to identify the target molecules regulated by certain compound. However, this method needs stable internal reference genes to analyze the expression change of the targets. In this study, the transcriptional stabilities of several traditional reference genes were evaluated in colon cancer cells treated with aspirin, and also, the suitable internal reference genes were screened by using a microarray and were further identified by using the geNorm and NormFinder softwares, and then were validated in more cell lines and xenografts. We have showed that three traditional internal reference genes, β-actin, GAPDH and α-tubulin, are not suitable for studying gene transcription in colon cancer cells treated with aspirin, and we have identified and validated TMEM208 and PQLC2 as the ideal internal reference genes for detecting the molecular targets of aspirin in colon cancer in vitro and in vivo. This study reveals stable internal reference genes for studying the target genes of aspirin in colon cancer, which will contribute to identify the molecular mechanism behind aspirin preventing colon cancer.

Constraining recent lead pollution sources in the North Pacific using ice core stable lead isotopes

NASA Astrophysics Data System (ADS)

Kreutz, K. J.; Osterberg, E. C.; Gross, B.; Handley, M.; Wake, C. P.; Yalcin, K.

2009-12-01

Trends and sources of lead aerosol pollution in the North Pacific boundary layer from 1970-2001 are investigated using a high-resolution ice core record recovered from Eclipse Icefield (3017 masl; St. Elias Mountains, Canada). Average Pb concentrations in the ice core are enriched 31.8 times above crustal values based on ratios with five crustal reference elements (La, Ce, Pr, Al and Ti), indicating that >90% of the Pb deposited is anthropogenic. Isotopic analyses (208Pb/207Pb and 206Pb/207Pb) confirm that the Pb deposited at Eclipse Icefield is predominantly anthropogenic. Annually averaged Pb concentrations range from 25.6 ng/l to 96.7 ng/l (67.6 ng/l mean) and show no long term trend for the 1970-2001 period, contrary to other ice core records from the North Atlantic and the North Pacific. The stable Pb isotope ratio (208Pb/207Pb and 206Pb/207Pb) field indicates that recent Eclipse Icefield Pb pollution represents a variable mixture of North American, Central Eurasian and Asian (Chinese and Japanese) emissions transported across the Pacific basin, with Chinese coal combustion likely being the primary source. Increasing 208Pb/207Pb and 206Pb/207Pb ratios from the 1970’s through 2001 reflect the progressive East Asian industrialization concurrent with a decrease in Eurasian Pb emissions. We compare Pb isotope results from the Eclipse Icefield to data recently acquired from Denali National Park, where snowpit samples were collected from the Kahiltna Pass region (3048 masl). Pb isotope data from both sites are used to evaluate the relative importance of Asian emissions at similar altitudes yet different latitudes.

Lead isotope ratios in tree bark pockets: an indicator of past air pollution in the Czech Republic.

PubMed

Conkova, M; Kubiznakova, J

2008-10-15

Tree bark pockets were collected at four sites in the Czech Republic with differing levels of lead (Pb) pollution. The samples, spanning 1923-2005, were separated from beech (Fagus sylvatica) and spruce (Picea abies). Elevated Pb content (0.1-42.4 microg g(-1)) reflected air pollution in the city of Prague. The lowest Pb content (0.3-2.6 microg g(-1)) was found at the Kosetice EMEP "background pollution" site. Changes in (206)Pb/(207)Pb and (208)Pb/(206)Pb isotope ratios were in agreement with operation times of the Czech main anthropogenic Pb sources. Shortly after the Second World War, the (206)Pb/(207)Pb isotope ratio in bark pockets decreased from 1.17 to 1.14 and the (208)Pb/(206)Pb isotope ratio increased from 2.12 to 2.16. Two dominant emission sources responsible for these changes, lignite and leaded petrol combustion, contributed to the shifts in Pb isotope ratios. Low-radiogenic petrol Pb ((206)Pb/(207)Pb of 1.11) lead to lower (206)Pb/(207)Pb in bark pockets over time. High-radiogenic lignite-derived Pb ((206)Pb/(207)Pb of 1.18 to 1.19) was detected in areas affected by coal combustion rather than by traffic.

Determination of Fusion Barrier Distributions from Quasielastic Scattering Cross Sections towards Superheavy Nuclei Synthesis

NASA Astrophysics Data System (ADS)

Tanaka, Taiki; Narikiyo, Yoshihiro; Morita, Kosuke; Fujita, Kunihiro; Kaji, Daiya; Morimoto, Kouji; Yamaki, Sayaka; Wakabayashi, Yasuo; Tanaka, Kengo; Takeyama, Mirei; Yoneda, Akira; Haba, Hiromitsu; Komori, Yukiko; Yanou, Shinya; Jean-Paul Gall, Benoît; Asfari, Zouhair; Faure, Hugo; Hasebe, Hiroo; Huang, Minghui; Kanaya, Jumpei; Murakami, Masashi; Yoshida, Atsushi; Yamaguchi, Takayuki; Tokanai, Fuyuki; Yoshida, Tomomi; Yamamoto, Shoya; Yamano, Yuki; Watanabe, Kenyu; Ishizawa, Satoshi; Asai, Masato; Aono, Ryuji; Goto, Shin-ichi; Katori, Kenji; Hagino, Kouichi

2018-01-01

In order to study the nucleus-nucleus interactions for syntheses of superheavy nuclei, we measured excitation functions for the quasielastic scattering of 48Ca+208Pb, 50Ti+208Pb, and 48Ca+248Cm using the gas-filled-type recoil ion separator GARIS. The quasielastic scattering events were clearly separated from deep-inelastic events by using GARIS and its focal plan detectors, except for high-incident-energy points. The quasielastic barrier distributions were successfully extracted for these systems, and compared with coupled-channels calculations. The results of the calculations indicate that vibrational and rotational excitations of the colliding nuclei, as well as neutron transfers before contact, strongly affect the structure of the barrier distribution. For the reactions of 48Ca+208Pb and 50Ti+208Pb, a local maximum of the barrier distribution occurred at the same energy as the peak of the 2n evaporation cross section of the system. On the other hand, for the hot fusion reaction of 48Ca+248Cm, the 4n evaporation cross section of the system peaks at energies well above the maximum of the barrier distribution. This may be attributed to the deformation of the target nucleus. We argue that these findings can be utilized to locate the optimal energy for future searches for undiscovered superheavy nuclei.

Study of isomeric states in 198,200,202,206Pb and 206Hg populated in fragmentation reactions

NASA Astrophysics Data System (ADS)

Lalović, N.; Rudolph, D.; Podolyák, Zs; Sarmiento, L. G.; Simpson, E. C.; Alexander, T.; Cortés, M. L.; Gerl, J.; Golubev, P.; Ameil, F.; Arici, T.; Bauer, Ch; Bazzacco, D.; Bentley, M. A.; Boutachkov, P.; Bowry, M.; Fahlander, C.; Gadea, A.; Gellanki, J.; Givechev, A.; Goel, N.; Górska, M.; Gottardo, A.; Gregor, E.; Guastalla, G.; Habermann, T.; Hackstein, M.; Jungclaus, A.; Kojouharov, I.; Kumar, R.; Kurz, N.; Lettmann, M.; Lizarazo, C.; Louchart, C.; Merchán, E.; Michelagnoli, C.; Moeller, Th; Moschner, K.; Patel, Z.; Pietralla, N.; Pietri, S.; Ralet, D.; Reese, M.; Regan, P. H.; Reiter, P.; Schaffner, H.; Singh, P.; Stahl, C.; Stegmann, R.; Stezowski, O.; Taprogge, J.; Thöle, P.; Wendt, A.; Wieland, O.; Wilson, E.; Wood, R.; Wollersheim, H.-J.; Birkenbach, B.; Bruyneel, B.; Burrows, I.; Clément, E.; Désesquelles, P.; Domingo-Pardo, C.; Eberth, J.; González, V.; Hess, H.; Jolie, J.; Judson, D. S.; Menegazzo, R.; Mengoni, D.; Napoli, D. R.; Pullia, A.; Quintana, B.; Rainovski, G.; Salsac, M. D.; Sanchis, E.; Simpson, J.; Valiente Dóbon, J. J.; AGATA Collaboration

2018-03-01

Isomeric states in isotopes in the vicinity of doubly-magic 208Pb were populated following reactions of a relativistic 208Pb primary beam impinging on a 9Be fragmentation target. Secondary beams of 198,200,202,206Pb and 206Hg were isotopically separated and implanted in a passive stopper positioned in the focal plane of the GSI Fragment Separator. Delayed γ rays were detected with the Advanced Gamma Tracking Array (AGATA). Decay schemes were re-evaluated and interpreted with shell-model calculations. The momentum-dependent population of isomeric states in the two-nucleon hole nuclei 206Pb/206Hg was found to differ from the population of multi neutron-hole isomeric states in 198,200,202Pb.

Comprehensive Development Plan in Office Skills. Final Performance Report.

ERIC Educational Resources Information Center

Waubonsee Community Coll., Sugar Grove, IL.

The Waubonsee Community College Comprehensive Development Plan in Office Skills served 208 students by assessment of basic skills and referral to appropriate programs or help with job skills and referral to employment during the 18-month grant period from December 1988 through June 30, 1990. The target population was minority women or economically…

Resolving neutrino mass hierarchy from supernova (anti)neutrino-nucleus reactions

NASA Astrophysics Data System (ADS)

Vale, Deni; Paar, Nils

2015-10-01

Recently a hybrid method has been introduced to determine neutrino mass hierarchy by simultaneous measurements of detector responses induced by antineutrino and neutrino fluxes from accretion and cooling phase of type II supernova. The (anti)neutrino-nucleus cross sections for 12C, 16O, 56Fe and 208Pb are calculated in the framework of relativistic nuclear energy density functional and weak interaction Hamiltonian, while the cross sections for inelastic scattering on free protons in mineral oil and water, p (v¯e,e+)n are obtained using heavy-baryon chiral perturbation theory. The simulations of (anti)neutrino fluxes emitted from a proto-neutron star in a core-collapse supernova include collective and Mikheyev-Smirnov-Wolfenstein effects inside star. It is shown that simultaneous use of ve/v¯e detectors with different target material allow to determine the neutrino mass hierarchy from the ratios of ve/v¯e induced particle emissions. The hybrid method favors detectors with heavier target nuclei (208Pb) for the neutrino sector, while for antineutrinos the use of free protons in mineral oil and water is more appropriate.

Prenatal metal exposure in the Middle East: imprint of war in deciduous teeth of children.

PubMed

Savabieasfahani, M; Ali, S Sadik; Bacho, R; Savabi, O; Alsabbak, M

2016-09-01

In war zones, the explosion of bombs, bullets, and other ammunition releases multiple neurotoxicants into the environment. The Middle East is currently the site of heavy environmental disruption by massive bombardments. A very large number of US military bases, which release highly toxic environmental contaminants, have also been erected since 2003. Current knowledge supports the hypothesis that war-created pollution is a major cause of rising birth defects and cancers in Iraq. We created elemental bio-imaging of trace elements in deciduous teeth of children with birth defects from Iraq. Healthy and naturally shed teeth from Lebanon and Iran were also analyzed for trace elements. Lead (Pb) was highest in teeth from children with birth defects who donated their teeth from Basra, Iraq (mean 0.73-16.74 (208)Pb/(43)Ca ppm, n = 3). Pb in healthy Lebanese and Iranian teeth were 0.038-0.382 (208)Pb/(43)Ca ppm (n = 4) and 0.041-0.31 (208)Pb/(43)Ca ppm (n = 2), respectively. Our hypothesis that increased war activity coincides with increased metal levels in deciduous teeth is confirmed by this research. Lead levels were similar in Lebanese and Iranian deciduous teeth. Deciduous teeth from Iraqi children with birth defects had remarkably higher levels of Pb. Two Iraqi teeth had four times more Pb, and one tooth had as much as 50 times more Pb than samples from Lebanon and Iran.

Effect of proteases on biofilm formation of the plastic-degrading actinomycete Rhodococcus ruber C208.

PubMed

Gilan, Irit; Sivan, Alex

2013-05-01

In most habitats, the vast majority of microbial populations form biofilms on solid surfaces, whether natural or artificial. These biofilms provide either increased physical support and/or a source of nutrients. Further modifications and development of biofilms are regulated by signal molecules secreted by the cells. Because synthetic polymers are not soluble in aqueous solutions, biofilm-producing bacteria may biodegrade such materials more efficiently than planktonic strains. Bacterial biofilms comprise bacterial cells embedded in self-secreted extracellular polymeric substances (EPS). Revealing the roles of each component of the EPS will enable further insight into biofilm development and the EPS structure-function relationship. A strain of Rhodococcus ruber (C208) displayed high hydrophobicity and formed a dense biofilm on the surface of polyethylene films while utilizing the polyolefin as carbon and energy sources. This study investigated the effects of several proteases on C208 biofilm formation and stability. The proteolysis of C208 biofilm gave conflicting results. Trypsin significantly reduced biofilm formation, and the resultant biofilm appeared monolayered. In contrast, proteinase K enhanced biofilm formation, which was robust and multilayered. Presumably, proteinase K degraded self-secreted proteases or quorum-sensing peptides, which may be involved in biofilm detachment processes, leading to a multilayered, nondispersed biofilm. © 2013 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.

Decay analysis of compound nuclei formed in reactions with exotic neutron-rich 9Li projectile and the synthesis of 217At* within the dynamical cluster-decay model

NASA Astrophysics Data System (ADS)

Kaur, Arshdeep; Kaushal, Pooja; Hemdeep; Gupta, Raj K.

2018-01-01

The decay of various compound nuclei formed via exotic neutron-rich 9Li projectile is studied within the dynamical cluster-decay model (DCM). Following the earlier work of one of us (RKG) and collaborators (M. Kaur et al. (2015) [1]), for an empirically fixed neck-length parameter ΔRemp, the only parameter in the DCM, at a given incident laboratory energy ELab, we are able to fit almost exactly the (total) fusion cross section σfus =∑x=16σxn for 9Li projectile on 208Pb and other targets, with σfus depending strongly on the target mass of the most abundant isotope and its (magic) shell structure. This result shows the predictable nature of the DCM. The neck-length parameter ΔRemp is fixed empirically for the decay of 217At* formed in 9Li + 208Pb reaction at a fixed laboratory energy ELab, and then the total fusion cross section σfus calculated for all other reactions using 9Li as a projectile on different targets. Apparently, this procedure could be used to predict σfus for 9Li-induced reactions where experimental data are not available. Furthermore, optimum choice of "cold" target-projectile combinations, forming "hot" compact configurations, are predicted for the synthesis of compound nucleus 217At* with 8Li + 209Pb as one of the target-projectile combination, or another (t , p) combination 48Ca + 169Tb, with a doubly magic 48Ca, as the best possibility.

Stable lead isotopes reveal a natural source of high lead concentrations to gasoline-contaminated groundwater

USGS Publications Warehouse

Landmeyer, J.E.; Bradley, P.M.; Bullen, T.D.

2003-01-01

Concentrations of total lead as high as 1,600 ??g/L were detected in gasoline-contaminated and uncontaminated groundwater at three gasoline-release sites in South Carolina. Total lead concentrations were highest in turbid groundwater samples from gasoline-contaminated and uncontaminated wells, whereas lower turbidity groundwater samples (collected using low-flow methods) had lower total lead concentrations. Dissolved lead concentrations in all wells sampled, however, were less than 15 ??g total lead/L, the current United States Environmental Protection Agency (US EPA) maximum contaminant level (MCL). Because many total lead concentrations exceeded the MCL, the source of lead to the groundwater system at two of the three sites was investigated using a stable lead isotope ratio approach. Plots of the stable isotope ratios of lead (Pb) in groundwater as 207Pb/206Pb versus 208Pb/206Pb, and 208Pb/204Pb versus 206Pb/204Pb were similar to ratios characteristic of lead-based minerals in local rocks of the southeastern US, and were not similar to the stable lead isotopes ratios characteristic of distant lead ore deposits such as Broken Hill, Australia, used to produce tetraethyl lead in gasoline products prior to its phase-out and ban in the United States. Moreover, the isotopic composition of dissolved lead was equivalent to the isotopic composition of total lead in turbid samples collected from the same well, suggesting that the majority of the lead detected in the groundwater samples was associated with sediment particulates of indigenous aquifer material, rather than lead associated with spilled leaded gasoline. The results of this investigation indicate that (1) lead detected at some gasoline-release sites may be derived from the local aquifer material, rather than the gasoline release, and consequently may affect site-specific remediation goals; (2) non-low flow groundwater sampling methods, such as a disposable bailer, may result in turbid groundwater samples and high total lead concentrations, and; (3) stable lead isotopes can be used to clarify the source of lead detected above permissible levels in gasoline-contaminated groundwater systems.

Tracing lead contamination in foods in the city of Kolkata, India.

PubMed

Das, Avijit; Krishna, Kvss; Kumar, Rajeev; Das, Anindya; Sengupta, Siladitya; Ghosh, Joy Gopal

2016-11-01

Lead isotopic ratios (LIR) of eight common food items, street dust, coal, diesel, sediments, lead ore and rainwater from India have been reported for the first time in this paper. This study characterized the source and extent of lead pollution in the different foodstuff consumed in Kolkata, a major metropolis of eastern India. The atmospheric lead input to the food items, sold openly in busy roadside markets of the city, has been quantified. The mean 207/206 and 208/206 LIRs of the eight food items ranged from 0.8847 to 0.8924 and 2.145 to 2.167, respectively. Diesel had the highest mean 207/206 and 208/206 values of 0.9015 and 2.1869, respectively, apart from the lead ore. The food items had a mean lead concentration between 3.78 and 43.35 mg kg -1 . The two ratio scatter plots of all the different environmental matrices were spread linearly between the uncontaminated Ichapur sediment and diesel. The 207/206 LIRs of the coal with a mean of 0.8777 did not fall in the linear trend, while the street dust and food samples overlapped strongly. The rainwater sample had a 207/206 LIR of 0.9007. Contaminated sediments in Dhapa, the repository of the city's municipal garbage, had a mean 207/206 LIR of 0.8658. The corresponding value obtained from the sewage-fed vegetable grown there was 0.8058. The present study indicated that diesel was one of the main contributor to Pb pollution. The atmospheric lead contribution to the food items was in the range of 68.48-86.66 %.

One century sedimentary record of lead and zinc pollution in Yangzong Lake, a highland lake in southwestern China.

PubMed

Zhang, Enlou; Liu, Enfeng; Shen, Ji; Cao, Yanmin; Li, Yanling

2012-01-01

Reconstruction of trace metal pollution histories and sources may help us to regulate current pollutant discharge. This is especially important for the highland lakes in southwestern China, which are facing trace metals pollution. We present sedimentary records of 11 metals accumulated in Yangzong Lake since the 1870's, a highland lake in southwestern China. Pollution of lead and zinc (Pb and Zn) was differentiated based on principal component analysis, geochemical normalization, and lead isotope ratios. Nearly all the metals as well as grain size composition show generally constant values before the mid-1980's, denoting stable detrital input in the catchment. Fluctuations in the concentrations of the metals as well as grain size composition since the mid-1980's indicate an increase in soil erosion with strengthened human disturbance in the catchment. After geochemical normalization, Pb and Zn showed constant values before 1990 AD and then a gradual increase in parallel with the variations in 208Pb/206Pb and 207Pb/206Pb ratios, indicating that Pb and Zn pollution occurred. Combining the data of 208pb/206Pb and 207Pb/6Pb ratios in the sediments of Yangzong Lake, leaded gasoline, Pb-Zn ore and coal, and consumption or production historical trends, we deduced that the enhanced Pb and Zn pollution in Yangzong Lake is caused primarily by ore mining and refining.

Photography, Motion Picture Film Cores and Spools, Performances, and Other Technical Information

DTIC Science & Technology

2000-01-01

process was an outgrowth of the Fred Waller Flexible Gunnery Trainer25 used to train aerial gunners to hit fast-moving air-borne targets. The realism ...34Travelling matte photography and the blue-screen system," published serially, Am. Cinemat , 44: 590-606, Oct. 1963; 45: 34-45, Jan. 1964; 208-210, 226-227

Spectroscopy of 204,206,208Rn and the systematic behavior of Z=86 isotopes

NASA Astrophysics Data System (ADS)

Horn, D.; Baktash, C.; Lister, C. J.

1981-11-01

A spectroscopic investigation of the radon isotopes 204,206,208Rn was performed by means of the reactions 192,194,196Pt(16O,4n)204,206,208Rn and 197Au(14N,5n)206Rn with 16O energies between 85 and 110 MeV and 14N energies between 80 and 94 MeV. γ-γ coincidences, pulsed beam yield functions, angular distributions, and pulsed beam isomeric decay rates were measured. The yrast and near-yrast level structure was established to J~15ℏ, and in each of the three nuclei two isomers above the known Jπ=8+ state were observed. The systematic trends for the Z=86 isotopes are compared with the behavior expected in a single particle model, and increased collectivity is found with decreasing neutron number. Analogies are made with the N=86 system. NUCLEAR REACTIONS 192,194,196Pt (16O,4n), E=85-110 MeV; 197Au(14N,5n), E=80-94 MeV. Measured Iγ(E,t), Iγ(θ), γ-γ(t). Deduced level sequences, Jπ, T12, transition rates. Continuous and pulsed beams, enriched targets, Ge(Li) detectors.

Characteristics of lead isotope ratios and elemental concentrations in PM 10 fraction of airborne particulate matter in Shanghai after the phase-out of leaded gasoline

NASA Astrophysics Data System (ADS)

Zheng, Jian; Tan, Mingguang; Shibata, Yasuyuki; Tanaka, Atsushi; Li, Yan; Zhang, Guilin; Zhang, Yuanmao; Shan, Zuci

The stable lead (Pb) isotope ratios and the concentrations of 23 elements, including heavy metals and toxic elements, were measured in the PM 10 airborne particle samples collected at seven monitoring sites in Shanghai, China, to evaluate the current elemental compositions and local airborne Pb isotope ratio characteristics. Some source-related samples, such as cement, coal and oil combustion dust, metallurgic dust, vehicle exhaust particles derived from leaded gasoline and unleaded gasoline, and polluted soils were analyzed for their Pb content and isotope ratio and compared to those observed in PM 10 samples. Airborne Pb concentration ranged from 167 to 854 ng/m 3 in the seven monitored sites with an average of 515 ng/m 3 in Shanghai, indicating that a high concentration of Pb remains in the air after the phasing out of leaded gasoline. Lead isotopic compositions in airborne particles ( 207Pb/ 206Pb, 0.8608±0.0018; 208Pb/ 206Pb, 2.105±0.005) are clearly distinct from the vehicle exhaust particles ( 207Pb/ 206Pb, 0.8854±0.0075; 208Pb/ 206Pb, 2.145±0.006), suggesting that the automotive lead is not currently the major component of Pb in the air. By using a binary mixing equation, a source apportionment based on 207Pb/ 206Pb ratios, indicates that the contribution from automotive emission to the airborne Pb is around 20%. The Pb isotope ratios obtained in the source-related samples confirmed that the major emission sources are metallurgic dust, coal combustion, and cement.

Isotope-ratio measurements of lead in NIST standard reference materials by multiple-collector inductively coupled plasma mass spectrometry.

PubMed

Platzner, I; Ehrlich, S; Halicz, L

2001-07-01

The capability of a second-generation Nu Instruments multiple collector inductively coupled plasma mass spectrometer (MC-ICP-MS) has been evaluated for precise and accurate isotope-ratio determinations of lead. Essentially the mass spectrometer is a double-focusing instrument of Nier-Johnson analyzer geometry equipped with a newly designed variable-dispersion ion optical device, enabling the measured ion beams to be focused into a fixed array of Faraday collectors and an ion-counting assembly. NIST SRM Pb 981, 982, and 983 isotopic standards were used. Addition of thallium to the lead standards and subsequent simultaneous measurement of the thallium and lead isotopes enabled correction for mass discrimination, by use of the exponential correction law and 205Tl/203Tl = 2.3875. Six measurements of SRM Pb-982 furnished the results 206Pb/204Pb = 36.7326(68), 207Pb/204Pb = 17.1543(30), 208Pb/204Pb = 36.7249(69), 207Pb/206Pb = 0.46700(1), and 208Pb/206Pb = 0.99979(2); the NIST-certified values were 36.738(37), 17.159(25), 36.744(50), 0.46707(20), and 1.00016(36), respectively. Direct isotope lead analysis in silicates can be performed without any chemical separation. NIST SRM 610 glass was dissolved and introduced into the MC-ICP-MS by means of a micro concentric nebulizer. The ratios observed were in excellent agreement with previously reported data obtained by TIMS and laser ablation MC-ICP-MS, despite the high Ca/Pb concentration ratio (200/1) and the presence of many other elements at levels comparable with that of lead. Approximately 0.2 microg lead are sufficient for isotope analysis with ratio uncertainties between 240 and 530 ppm.

Experimental approach to measure thick target neutron yields induced by heavy ions for shielding

NASA Astrophysics Data System (ADS)

Trinh, N. D.; Fadil, M.; Lewitowicz, M.; Brouillard, C.; Clerc, T.; Damoy, S.; Desmezières, V.; Dessay, E.; Dupuis, M.; Grinyer, G. F.; Grinyer, J.; Jacquot, B.; Ledoux, X.; Madeline, A.; Menard, N.; Michel, M.; Morel, V.; Porée, F.; Rannou, B.; Savalle, A.

2017-09-01

Double differential (angular and energy) neutron distributions were measured using an activation foil technique. Reactions were induced by impinging two low-energy heavy-ion beams accelerated with the GANIL CSS1 cyclotron: (36S (12 MeV/u) and 208Pb (6.25 MeV/u)) onto thick natCu targets. Results have been compared to Monte-Carlo calculations from two codes (PHITS and FLUKA) for the purpose of benchmarking radiation protection and shielding requirements. This comparison suggests a disagreement between calculations and experiment, particularly for high-energy neutrons.

A View from the Aisle Revisited: Delight and Outrage in the Classroom

ERIC Educational Resources Information Center

Swanson, Scott R.; Azab, Carol; Davis, J. Charlene

2015-01-01

This research explores marketing students' emotional reactions to classroom encounters. We identify what types of critical incidents lead to specific emotional outcomes. The study included a sample of 1,208 marketing undergraduates. Findings confirm the viability of the taxonomies identified by Swanson and Davis (2000). We expand their framework…

40 CFR 468.15 - Pretreatment standards for new sources (PSNS).

Code of Federal Regulations, 2014 CFR

2014-07-01

...—pounds per 1,000,000 off-pounds of copper or copper alloy hot rolled Chromium 0.038 0.015 Copper 0.131 0... Chromium 0.140 0.056 Copper 0.485 0.231 Lead 0.037 0.034 Nickel 0.208 0.140 Zinc 0.386 0.159 TTO 0.128 0... copper alloy drawn Chromium 0.031 0.012 Copper 0.108 0.051 Lead 0.0085 0.0076 Nickel 0.046 0.031 Zinc 0...

40 CFR 468.15 - Pretreatment standards for new sources (PSNS).

Code of Federal Regulations, 2013 CFR

2013-07-01

...—pounds per 1,000,000 off-pounds of copper or copper alloy hot rolled Chromium 0.038 0.015 Copper 0.131 0... Chromium 0.140 0.056 Copper 0.485 0.231 Lead 0.037 0.034 Nickel 0.208 0.140 Zinc 0.386 0.159 TTO 0.128 0... copper alloy drawn Chromium 0.031 0.012 Copper 0.108 0.051 Lead 0.0085 0.0076 Nickel 0.046 0.031 Zinc 0...

40 CFR 468.15 - Pretreatment standards for new sources (PSNS).

Code of Federal Regulations, 2012 CFR

2012-07-01

...—pounds per 1,000,000 off-pounds of copper or copper alloy hot rolled Chromium 0.038 0.015 Copper 0.131 0... Chromium 0.140 0.056 Copper 0.485 0.231 Lead 0.037 0.034 Nickel 0.208 0.140 Zinc 0.386 0.159 TTO 0.128 0... copper alloy drawn Chromium 0.031 0.012 Copper 0.108 0.051 Lead 0.0085 0.0076 Nickel 0.046 0.031 Zinc 0...

Anthropogenic and natural lead isotopes in Fe-hydroxides and Fe-sulphates in a watershed associated with arsenic-enriched groundwater, Maine, USA

USGS Publications Warehouse

Ayuso, Robert A.; Foley, Nora K.

2008-01-01

A survey of the natural and anthropogenic sources of lead contributing to secondary minerals in sulphidic schists associated with arsenic-enriched groundwater in Coastal Maine shows that the most likely source is natural Pb, particularly from coexisting sulphide minerals. The secondary minerals also reflect notable contributions from anthropogenic Pb. The Pb isotopes establish pathways by which Pb, and by inference As, could have been transported from As-bearing minerals (arsenian pyrite, arsenopyrite, lollingite, orpiment, arsenic oxide and others), via sulphide oxidation or carbonation reactions into multiple generations of secondary minerals (goethite, hematite, jarosite, natrojarosite and others). Lead isotopic compositions of the sulphides and secondary minerals determined by thermal ionization mass spectrometry (n=53) range widely. Lead and As contents of the sulphides and secondary minerals overlap, and are generally positively correlated. Pyrite, the dominant sulphide in sulphidic schists associated with As-enriched groundwater in Coastal Maine, has values of 206Pb/204Pb from 18.186 to 18.391, 207Pb/204Pb from 15.617 to 15.657, 208Pb/204Pb from 38.052 to 38.210, 206Pb/207Pb from c. 1.1625 to 1.1760 and 208Pb/207Pb from c. 2.4276 to 2.4394. Mixtures of Fe-hydroxide and oxide minerals (predominantly goethite and hematite) and secondary Fe-sulphate minerals (jarosite, natrojarosite, rozenite and melanterite) in the sulphidic schists have overlapping but generally higher values of 206Pb/204Pb from 18.495 to 19.747 (one sample at 21.495), 207Pb/204Pb from 15.595 to 15.722 (one sample at 15.839), 208Pb/204Pb from 38.186 to 39.162,206Pb/207Pb from c.1.1860 to 1.2575 (one sample at 1.3855) and 208Pb/207Pb from c. 2.4441 to 2.4865 than the sulphides. Sulphides from Zn-Pb metal mines are somewhat less radiogenic than sulphides from the schists. Other sulphides (mostly pyrite) associated with pegmatites and granitic rocks are heterogeneous and more radiogenic than the pyrite-rich sulphidic schists. Sulphides from other regional bedrock units also have heterogeneous isotope values. Lead isotopic compositions of the sulphides from the sulphidic schists and coexisting Fe-oxides and Fe-sulphates produced by weathering and alteration overlap, but the secondary minerals extend toward more radiogenic values that broadly indicate the addition of Pb from anthropogenic origin. As a component of Pb from extensively used arsenical pesticides may also be present in the secondary minerals, the range in Pb isotope values is consistent with multiple sources: natural Pb from the schists and anthropogenic Pb (industrial and possibly from agricultural activities). Contributions from past mining activities or from other bedrock sources are not implicated.

Double folding analysis of 3He elastic and inelastic scattering to low lying states on 90Zr, 116Sn and 208Pb at 270 MeV

NASA Astrophysics Data System (ADS)

Marwa, N. El-Hammamy

2015-03-01

The experimental data on elastic and inelastic scattering of 270 MeV 3He particles to several low lying states in 90Zr, 116Sn and 208Pb are analyzed within the double folding model (DFM). Fermi density distribution (FDD) of target nuclei is used to obtain real potentials with different powers. DF results are introduced into a modified DWUCK4 code to calculate the elastic and inelastic scattering cross sections. Two choices of potentials form factors are used; Woods Saxon (WS) and Woods Saxon Squared (WS2) for real potential, while the imaginary part is taken as phenomenological Woods Saxon (PWS) and phenomenological Woods Saxon Squared (PWS2). This comparison provides information about the similarities and differences of the models used in calculations.

11Li Breakup on 208 at energies around the Coulomb barrier.

PubMed

Fernández-García, J P; Cubero, M; Rodríguez-Gallardo, M; Acosta, L; Alcorta, M; Alvarez, M A G; Borge, M J G; Buchmann, L; Diget, C A; Falou, H A; Fulton, B R; Fynbo, H O U; Galaviz, D; Gómez-Camacho, J; Kanungo, R; Lay, J A; Madurga, M; Martel, I; Moro, A M; Mukha, I; Nilsson, T; Sánchez-Benítez, A M; Shotter, A; Tengblad, O; Walden, P

2013-04-05

The inclusive breakup for the (11)Li + (208)Pb reaction at energies around the Coulomb barrier has been measured for the first time. A sizable yield of (9)Li following the (11)Li dissociation has been observed, even at energies well below the Coulomb barrier. Using the first-order semiclassical perturbation theory of Coulomb excitation it is shown that the breakup probability data measured at small angles can be used to extract effective breakup energy as well as the slope of B(E1) distribution close to the threshold. Four-body continuum-discretized coupled-channels calculations, including both nuclear and Coulomb couplings between the target and projectile to all orders, reproduce the measured inclusive breakup cross sections and support the presence of a dipole resonance in the (11)Li continuum at low excitation energy.

Lead Isotope Characteristics of the Mindyak Gold Deposit, Southern Urals: Evidence for the Source of Metals

NASA Astrophysics Data System (ADS)

Chugaev, A. V.; Znamensky, S. E.

2018-01-01

The isotopic composition of Pb in pyrite of the Mindyak orogenic gold deposit located in the Main Ural Fault Zone, the Southern Urals, has been studied by the high-precision MC-ICP-MS method. Orebodies at the deposit are composed of early pyrite and late polysulfide-carbonate-quartz mineral assemblages. The orebodies are localized in olistostrome with carbonaceous clayey-cherty cement. Pyrites from early and late mineral assemblages are close in Pb isotope ratios. For early pyrite 206Pb/204Pb = 18.250-18.336, 207Pb/204Pb = 15.645-15.653, 208Pb/204Pb = 38.179-38.461; while for late pyrite 206Pb/204Pb = 18.102-18.378, 207Pb/204Pb = 15.635-15.646, 208Pb/204Pb = 38.149-38.320. The model parameters μ2 (238U/204Pb = 9.91 ± 2), ω2 (232Th/204Pb = 38.5 ± 4), and 232Th/238U = 3.88 ± 3 indicate that an upper crustal Pb source played a leading role in ore formation. Carbonaceous shale as an olistostrome cement and syngenetic sulfide mineralization are considered to be the main Pb sources of both early and late mineral assemblages. An additional recept in apparently magmatic lead is suggested for the late veinlet mineralization. The involvement of lead from several sources in ore formation is consistent with the genetic model, which assumes a two-stage formation of orebodies at the Mindyak deposit.

40 CFR Appendix G to Part 50 - Reference Method for the Determination of Lead in Total Suspended Particulate Matter

Code of Federal Regulations, 2014 CFR

2014-07-01

... Study of Procedures Evaluated by the Federal Advisory Committee on Detection and Quantitation Approaches... placed in a heated ultrasonic bath for one hour to facilitate the extraction of Pb. Following... the summation of signal intensities for the isotopic masses 206, 207, and 208. In most cases, the...

Decommissioning and PIE of the MEGAPIE spallation target

DOE Office of Scientific and Technical Information (OSTI.GOV)

Latge, C.; Henry, J.; Wohlmuther, M.

2013-07-01

A key experiment in the Accelerated Driven Systems roadmap, the MEGAwatt PIlot Experiment (MEGAPIE) (1 MW) was initiated in 1999 in order to design and build a liquid lead-bismuth spallation target, then to operate it into the Swiss spallation neutron facility SINQ at Paul Scherrer Institute. The target has been designed, manufactured, and tested during integral tests, before irradiation carried out end of 2006. During irradiation, neutron and thermo hydraulic measurements were performed allowing deep interpretation of the experiment and validation of the models used during design phase. The decommissioning, Post Irradiation Examinations and waste management phases were defined properly.more » The phases dedicated to cutting, sampling, cleaning, waste management, samples preparation and shipping to various laboratories were performed by PSI teams: all these phases constitute a huge work, which allows now to perform post-irradiation examination (PIE) of structural material, irradiated in relevant conditions. Preliminary results are presented in the paper, they concern chemical characterization. The following radio-nuclides have been identified by γ-spectrometry: {sup 60}Co, {sup 101}Rh, {sup 102}Rh, {sup 108m}Ag, {sup 110m}Ag, {sup 133}Ba, {sup 172}Hf/Lu, {sup 173}Lu, {sup 194}Hg/Au, {sup 195}Au, {sup 207}Bi. For some of these nuclides the activities can be easily evaluated from γ-spectrometry results ({sup 207}Bi, {sup 194}Hg/Au), while other nuclides can only be determined after chemical separations ({sup 108m}Ag, {sup 110m}Ag, {sup 195}Au, {sup 129}I, {sup 36}Cl and α-emitting {sup 208-210}Po). The concentration of {sup 129}I is lower than expected. The chemical analysis already performed on spallation and corrosion products in the lead-bismuth eutectic (LBE) are very relevant for further applications of LBE as a spallation media and more generally as a coolant.« less

Face Recognition and Processing in a Mini Brain

DTIC Science & Technology

2007-09-28

flying honeybees ( Apis mellifera ) as a model to understand how a non-mammalian brain learns to recognise human faces. Individual bees were trained...understand how a non-mammalian brain processes human faces is the honeybee (J Exp Biol 2005 v208p4709). Individual free flying honeybees ( Apis ... mellifera ) were provided with differential conditioning to achromatic target and distractor face images. Bee acquisition reached >70% correct choices

Efficacy of hepatitis B virus ribonuclease H inhibitors, a new class of replication antagonists, in FRG human liver chimeric mice.

PubMed

Long, Kelly R; Lomonosova, Elena; Li, Qilan; Ponzar, Nathan L; Villa, Juan A; Touchette, Erin; Rapp, Stephen; Liley, R Matt; Murelli, Ryan P; Grigoryan, Alexandre; Buller, R Mark; Wilson, Lisa; Bial, John; Sagartz, John E; Tavis, John E

2018-01-01

Chronic hepatitis B virus infection cannot be cured by current therapies, so new treatments are urgently needed. We recently identified novel inhibitors of the hepatitis B virus ribonuclease H that suppress viral replication in cell culture. Here, we employed immunodeficient FRG KO mice whose livers had been engrafted with primary human hepatocytes to ask whether ribonuclease H inhibitors can suppress hepatitis B virus replication in vivo. Humanized FRG KO mice infected with hepatitis B virus were treated for two weeks with the ribonuclease H inhibitors #110, an α-hydroxytropolone, and #208, an N-hydroxypyridinedione. Hepatitis B virus viral titers and S and e antigen plasma levels were measured. Treatment with #110 and #208 caused significant reductions in plasma viremia without affecting hepatitis B virus S or e antigen levels, and viral titers rebounded following treatment cessation. This is the expected pattern for inhibitors of viral DNA synthesis. Compound #208 suppressed viral titers of both hepatitis B virus genotype A and C isolates. These data indicate that Hepatitis B virus replication can be suppressed during infection in an animal by inhibiting the viral ribonuclease H, validating the ribonuclease H as a novel target for antiviral drug development. Copyright © 2017 Elsevier B.V. All rights reserved.

Production of n-rich Nuclei along the Closed Shell N=126 in the collision 136Xe + 208Pb @E lab =870 MeV

NASA Astrophysics Data System (ADS)

Quero, D.; Vardaci, E.; Kozulin, E. M.; Zagrebaev, V. A.; Corradi, L.; Pulcini, A.; La Rana, G.; Itkis, I. M.; Knyazheva, G. N.; Novikov, K.; Harca, I.; Fioretto, E.; Stefanini, A. M.; Montanari, D.; Montagnoli, G.; Scarlassara, F.; Szilner, S.; Mijatović, T.; Trzaska, W. H.

2018-05-01

Multi-nucleon transfer reactions are nowadays the only known mean to produce neutron-rich nuclei in the Terra Incognita. The closed-shell region N=126 is crucial for both studying shell-quenching in exotic nuclei and the r-process, being its last “waiting-point”. The choice of suitable reactions is challenging and a favorable case is 136Xe+208Pb, near the Coulomb barrier, because their neutron shell-closures play a stabilizing role, favoring the proton-transfer from lead to xenon. TOF-TOF data were analyzed to reconstruct the mass-energy distribution of the primary fragments. Preliminary results of an experiment held at Laboratori Nazionali di Legnaro with PRISMA, aimed at A and Z identification of the products, will be shown.

Core excitations across the neutron shell gap in 207Tl

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wilson, E.; Podolyák, Zs.; Grawe, H.

2015-05-05

The single closed-neutron-shell, one proton–hole nucleus 207Tl was populated in deep-inelastic collisions of a 208Pb beam with a 208Pb target. The yrast and near-yrast level scheme has been established up to high excitation energy, comprising an octupole phonon state and a large number of core excited states. Based on shell-model calculations, all observed single core excitations were established to arise from the breaking of the N=126 neutron core. While the shell-model calculations correctly predict the ordering of these states, their energies are compressed at high spins. It is concluded that this compression is an intrinsic feature of shell-model calculations usingmore » two-body matrix elements developed for the description of two-body states, and that multiple core excitations need to be considered in order to accurately calculate the energy spacings of the predominantly three-quasiparticle states.« less

Diabetes Self-Management Education Enhanced by the Low Vision Professional

ERIC Educational Resources Information Center

Sokol-McKay, Debra A.

2007-01-01

Diabetes currently affects 20.8 million people in the United States and is the leading cause of blindness in people between the ages of 20 and 74 years. The author uses a fictional but typical example to explain the ways in which low vision specialists can improve the diabetes self-management program of a person with low vision and demonstrates…

Lead isotope profiling in dairy calves.

PubMed

Buchweitz, John; McClure-Brinton, Kimberly; Zyskowski, Justin; Stensen, Lauren; Lehner, Andreas

2015-03-01

Lead (Pb) is a common cause of heavy metal poisonings in cattle. Sources of Pb on farms include crankcase oil, machinery grease, batteries, plumbing, and paint chips. Consequently, consumption of Pb from these sources may negatively impact animal health and Pb may be inadvertently introduced into the food supply. Therefore, the scope of poisoning incidents must be clearly assessed and sources of intoxication identified and strategies to mitigate exposure evaluated and implemented to prevent future exposures. Stable isotope analysis by inductively-coupled plasma mass spectrometry (ICP-MS) has proven itself of value in forensic investigations. We report on the extension of Pb stable isotope analysis to bovine tissues and profile comparisons with paint chips and soils collected from an affected dairy farm to elucidate the primary source. Pb occurs naturally as four stable isotopes: (204)Pb, (206)Pb, (207)Pb, and (208)Pb. Herein a case is reported to illustrate the use of (207)Pb/(206)Pb and (208)Pb/(206)Pb ratios to link environmental sources of exposure with tissues from a poisoned animal. Chemical Pb profiling provides a valuable tool for field investigative approaches to Pb poisoning in production agriculture and is applicable to subclinical exposures. Copyright © 2014 Elsevier Inc. All rights reserved.

Measurements of neutron skin in calcium and lead

NASA Astrophysics Data System (ADS)

Michaels, Robert

2017-01-01

Measurement of the parity-violating electron scattering asymmetry from 208Pb has demonstrated a new opportunity at Jefferson Lab to measure the weak charge form factor and hence pin down the neutron radius in nuclei in a relatively clean and model-independent way. This is because the Z boson of the weak interaction couples primarily to neutrons. We will describe the PREX and CREX experiments on 208Pb and 48Ca respectively. PREX-I ran in 2010, and CREX and a second run of PREX are currently in preparation. These are both doubly-magic nuclei whose first excited state can be discriminated by the high resolution spectrometers at JLab. The heavier lead nucleus, with a neutron excess, provides an interpretation of the neutron skin thickness in terms of properties of bulk neutron matter. For the lighter 48Ca nucleus, which is also rich in neutrons, microscopic nuclear theory calculations are feasible and are sensitive to poorly constrained 3-neutron forces. The measuements are a fundamental test of nuclear structure with applications to heavy ion research and neutron stars. Jefferson Science Associates, LLC, which operates Jefferson Lab for the U.S. DOE under U.S. DOE contract DE-AC05-060R23177.

Application of droplet digital PCR to determine copy number of endogenous genes and transgenes in sugarcane.

PubMed

Sun, Yue; Joyce, Priya Aiyar

2017-11-01

Droplet digital PCR combined with the low copy ACT allele as endogenous reference gene, makes accurate and rapid estimation of gene copy number in Q208 A and Q240 A attainable. Sugarcane is an important cultivated crop with both high polyploidy and aneuploidy in its 10 Gb genome. Without a known copy number reference gene, it is difficult to accurately estimate the copy number of any gene of interest by PCR-based methods in sugarcane. Recently, a new technology, known as droplet digital PCR (ddPCR) has been developed which can measure the absolute amount of the target DNA in a given sample. In this study, we deduced the true copy number of three endogenous genes, actin depolymerizing factor (ADF), adenine phosphoribosyltransferase (APRT) and actin (ACT) in three Australian sugarcane varieties, using ddPCR by comparing the absolute amounts of the above genes with a transgene of known copy number. A single copy of the ACT allele was detected in Q208 A , two copies in Q240 A , but was absent in Q117. Copy number variation was also observed for both APRT and ADF, and ranged from 9 to 11 in the three tested varieties. Using this newly developed ddPCR method, transgene copy number was successfully determined in 19 transgenic Q208 A and Q240 A events using ACT as the reference endogenous gene. Our study demonstrates that ddPCR can be used for high-throughput genetic analysis and is a quick, accurate and reliable alternative method for gene copy number determination in sugarcane. This discovered ACT allele would be a suitable endogenous reference gene for future gene copy number variation and dosage studies of functional genes in Q208 A and Q240 A .

Dynamical Cluster-decay Model (DCM) applied to 9Li+208Pb reaction

NASA Astrophysics Data System (ADS)

Kaur, Arshdeep; Hemdeep; Kaushal, Pooja; Behera, Bivash R.; Gupta, Raj K.

2017-10-01

The decay mechanism of 217At* formed in 9Li+208Pb reaction is studied within the dynamical cluster-decay model (DCM) at various center-of-mass energies. The aim is to see the behavior of a light neutron-rich radioactive beam on a doubly-magic target nucleus for the (total) fusion cross section σfus and the individual decay channel cross sections. Experimentally, only the isotopic yield of heavy mass residues * 211- 214At [equivalently, the light-particles (LPs) evaporation residue cross sections σxn for x = 3- 6 neutrons emission] are measured, with the fusion-fission (ff) component σff taken zero. For a fixed neck-length parameter ΔR, the only parameter in the DCM, we are able to fit σfus =∑x=16σxn almost exactly for 9Li on 208Pb at all E c . m .'s. However, the observed individual decay channels (3n-6n) are very poorly fitted, with unobserved channels (1n, 2n) and σff strongly over-estimated. Different ΔR values, meaning thereby different reaction time scales, are required to fit individually both the observed and unobserved evaporation residue channels (1n-6n) and σff, but then the compound nucleus (CN) contribution σCN is very small (< 1%), and the non-compound nucleus (nCN) decay cross section σnCN contributes the most towards total σfus (=σCN +σnCN). Thus, the 9Li induced reaction on doubly-magic 208Pb is more of a quasi-fission-like nCN decay, which is further analyzed in terms of the statistical CN formation probability PCN and CN survival probability Psurv. For the reaction under study, PCN < < 1 and Psurv → 1, in particular at above barrier energies.

22 CFR 208.105 - Does this part apply to me?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Does this part apply to me? 208.105 Section 208.105 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) General § 208.105 Does this part apply to me? Portions of this part (see table at § 208.25(b...

22 CFR 208.105 - Does this part apply to me?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Does this part apply to me? 208.105 Section 208.105 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) General § 208.105 Does this part apply to me? Portions of this part (see table at § 208.25(b...

Occurrence of simultaneous cathodal-anodal capture with left ventricular quadripolar leads for cardiac resynchronization therapy: an electrocardiogram evaluation.

PubMed

Occhetta, Eraldo; Dell'Era, Gabriele; Giubertoni, Ailia; Magnani, Andrea; Rametta, Francesco; Blandino, Alessandro; Magnano, Vincenzo; Malacrida, Maurizio; Marino, Paolo

2017-04-01

The occurrence of left ventricular (LV) anodal activation during pacing with modern multipolar cardiac resynchronization therapy (CRT) systems has never been reported. The aim of our study was to demonstrate, by means of electrocardiogram (ECG) analysis, the occurrence of simultaneous cathodal-anodal LV capture with quadripolar LV leads. We studied 10 first-time recipients of a CRT device equipped with a quadripolar LV lead. During follow-up, standard supine 12-lead ECGs were obtained in available cathode-to-anode LV pacing configurations with a pulse amplitude equal to twice the pacing threshold. The occurrence of simultaneous cathodal-anodal LV capture was defined as the presence of variations in electrocardiographic ventricular activation (EVA) when the distal tip (cathode)-to-device can (anode) pacing configuration was compared with the distal tip (cathode)-to-proximal ring (anode) configuration. In eight patients, we found differences in EVA when different LV sites were paced through the unipolar LV tip and unipolar LV ring configurations. In these patients, a difference in EVA was detected in 61.5% (59 of 96) of the ECG leads (marked difference in 31.3%, slight difference in 30.2%). Changes in EVA between unipolar tip-to-can and bipolar tip-to-ring pacing that were suggestive of cathodal-anodal LV capture were found in six patients. In these patients, a total of 30 (41.7%) ECG leads showed a difference in EVA (marked difference in 20.8%, slight difference in 20.8%). In our experience, additional anodal capture by the proximal LV ring during LV pacing is provable in most recipients of a resynchronization device equipped with a multipolar LV lead. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2016. For permissions please email: journals.permissions@oup.com.

Hybrid method to resolve the neutrino mass hierarchy by supernova (anti)neutrino induced reactions

NASA Astrophysics Data System (ADS)

Vale, D.; Rauscher, T.; Paar, N.

2016-02-01

We introduce a hybrid method to determine the neutrino mass hierarchy by simultaneous measurements of responses of at least two detectors to antineutrino and neutrino fluxes from accretion and cooling phases of core-collapse supernovae. The (anti)neutrino-nucleus cross sections for 56Fe and 208Pb are calculated in the framework of the relativistic nuclear energy density functional and weak interaction Hamiltonian, while the cross sections for inelastic scattering on free protons p(bar nue,e+)n are obtained using heavy-baryon chiral perturbation theory. The modelling of (anti)neutrino fluxes emitted from a protoneutron star in a core-collapse supernova include collective and Mikheyev-Smirnov-Wolfenstein effects inside the exploding star. The particle emission rates from the elementary decay modes of the daughter nuclei are calculated for normal and inverted neutrino mass hierarchy. It is shown that simultaneous use of (anti)neutrino detectors with different target material allows to determine the neutrino mass hierarchy from the ratios of νe- and bar nue-induced particle emissions. This hybrid method favors neutrinos from the supernova cooling phase and the implementation of detectors with heavier target nuclei (208Pb) for the neutrino sector, while for antineutrinos the use of free protons in mineral oil or water is the appropriate choice.

Study of SHE at SHIP

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hofmanna, Sigurd; Institut fuer Kernphysik, Goethe-Universitaet Frankfurt, Max von Laue-Strasse 1, 60438 Frankfurt am Main

2010-06-01

The nuclear shell model predicts that the next doubly magic shell-closure beyond {sup 208}Pb is at a proton number Z = 114, 120, or 126 and at a neutron number N = 184. The outstanding aim of experimental investigations is the exploration of this region of spherical 'SuperHeavy Elements'(SHEs). Experimental methods are described, which allowed for the identification of elements produced on a cross-section level of about 1 pb. Reactions used at SHIP are based on targets of lead and uranium. The decay data reveal that for the heaviest elements, the dominant decay mode is alpha emission, not fission. Decaymore » properties as well as reaction cross-sections are compared with results obtained at other laboratories and with results of theoretical investigations. Finally, plans are presented for the further development of the experimental set-up and the application of new techniques, as for instance the precise mass measurement of the produced nuclei using ion traps. At increased sensitivity, detailed exploration of the region of spherical SHEs will start, after first steps on the island of SHEs were made in recent years.« less

Studies of SHE at SHIP

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hofmann, Sigurd; Institut fuer Kernphysik, Goethe-Universitaet Frankfurt, Max von Laue-Strasse 1, 60438 Frankfurt am Main

2010-04-30

The nuclear shell model predicts that the next doubly magic shell-closure beyond {sup 208}Pb is at a proton number Z = 114, 120, or 126 and at a neutron number N = 184. The outstanding aim of experimental investigations is the exploration of this region of spherical 'Super-Heavy Elements'(SHEs). Experimental methods are described, which allowed for the identification of elements produced on a cross-section level of about 1 pb. Reactions used at SHIP are based on targets of lead and uranium. The decay data reveal that for the heaviest elements, the dominant decay mode is alpha emission, not fission. Decaymore » properties as well as reaction cross-sections are compared with results obtained at other laboratories and with results of theoretical investigations. Finally, plans are presented for the further development of the experimental setup and the application of new techniques, as for instance the precise mass measurement of the produced nuclei using ion traps. At increased sensitivity, detailed exploration of the region of spherical SHEs will start, after first steps on the island of SHEs were made in recent years.« less

22 CFR 208.345 - What happens if I fail to disclose information required under § 208.335?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false What happens if I fail to disclose information... Disclosing Information-Primary Tier Participants § 208.345 What happens if I fail to disclose information required under § 208.335? If we later determine that you failed to disclose information under § 208.335...

22 CFR 208.345 - What happens if I fail to disclose information required under § 208.335?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false What happens if I fail to disclose information... Disclosing Information-Primary Tier Participants § 208.345 What happens if I fail to disclose information required under § 208.335? If we later determine that you failed to disclose information under § 208.335...

Investigation of different C-backings for targets

NASA Astrophysics Data System (ADS)

Hübner, Annett; Kindler, Birgit; Lommel, Bettina; Steiner, Jutta; Yakusheva, Vera; Khuyagbaatar, J.; Hinde, David J.; Dasgupta, Mahananda

2018-05-01

For a special application, carbon-backings with a very flat surface, microscopically as well as macroscopically, were needed as backings for targets of enriched isotopes. However, betaine-sucrose routinely applied at GSI as parting agent for carbon deposition results in a microscopically rough surface which was not perfectly satisfying the experimental requirements. For these targets we investigated the carbon-backing quality in relation to the applied different parting agents and different deposition processes. In this paper we report on the yield, on the structure of the carbon layers and the deposited target layer of 208PbS, 206PbS, and 142NdF3 depending on the parting agent, the thickness and the deposition methods. We report on elastic scattering experiments with a 48Ti-beam demonstrating the influence of the structure of the carbon backing on the experimental results.

Association between circulating microRNA-208a and severity of coronary heart disease.

PubMed

Zhang, Yao; Li, Hai-Hong; Yang, Rui; Yang, Bai-Jing; Gao, Zhao-Yu

2017-09-01

Circulating microRNA (miR)-208a is specifically expressed in the heart muscle, which is involved in the regulation of myosin during cardiac development. Previous studies reported that cardiac-specific miR-208a level is significantly higher in plasma of coronary heart disease (CHD) patients. However, whether it correlates with severity of CHD, has never been elucidated before. The aim of this study was to explore the association between miR-208a and the presence and severity of CHD. Samples were collected from 290 CHD patients and 110 subjects with angiographic exclusion of CHD. Circulating miRNA-208a expression was detected using quantitative real-time PCR. The Gensini score was used to evaluate the severity of coronary stenotic lesions. Expression of miRNA-208a was identified on the basis of the quartiles of the Gensini score, and association between the miRNA-208a levels and CHD was analyzed. Diagnostic potential of miR-208a of CHD was performed by ROC analysis. CHD patients had higher miRNA-208a expression (1.61, 0.45-3.86 vs. 0.66, 0.11-1.42, p < .001), and the biomarker level significantly increased following an increasing the Gensini score (p < .001). Gensini score was significantly associated with miRNA-208a expression (r = 0.8525, p < .001). The optimal cut-off value of the relative level of miR-208a was with a specificity of 93.6% and a sensitivity of 75.5%. The AUC of miR-208a was 0.919 (95% CI, 0.893-0.945; p < .001). These preliminary results suggest that the expression of miR-208a may be associated with atherogenesis. The level of circulating miR-208a in predicting the severity of coronary atherosclerosis may have a relatively certain value.

Case-Only Gene–Environment Interaction Between ALAD tagSNPs and Occupational Lead Exposure in Prostate Cancer

PubMed Central

Neslund-Dudas, Christine; Levin, Albert M.; Rundle, Andrew; Beebe-Dimmer, Jennifer; Bock, Cathryn H.; Nock, Nora L.; Jankowski, Michelle; Datta, Indrani; Krajenta, Richard; Dou, Q. Ping; Mitra, Bharati; Tang, Deliang; Rybicki, Benjamin A.

2014-01-01

BACKGROUND Black men have historically had higher blood lead levels than white men in the U.S. and have the highest incidence of prostate cancer in the world. Inorganic lead has been classified as a probable human carcinogen. Lead (Pb) inhibits delta-aminolevulinic acid dehydratase (ALAD), a gene recently implicated in other genitourinary cancers. The ALAD enzyme is involved in the second step of heme biosynthesis and is an endogenous inhibitor of the 26S proteasome, a master system for protein degradation and a current target of cancer therapy. METHODS Using a case-only study design, we assessed potential gene–environment (G × E) interactions between lifetime occupational Pb exposure and 11 tagSNPs within ALAD in black (N = 260) and white (N = 343) prostate cancer cases. RESULTS Two ALAD tagSNPs in high linkage disequilibrium showed significant interaction with high Pb exposure among black cases (rs818684 interaction odds ratio or IOR = 2.73, 95% CI 1.43–5.22, P = 0.002; rs818689 IOR = 2.20, 95% CI 1.15–4.21, P = 0.017) and an additional tagSNP, rs2761016, showed G × E interaction with low Pb exposure (IOR = 2.08, 95% CI 1.13– 3.84, P = 0.019). Further, the variant allele of rs818684 was associated with a higher Gleason grade in those with high Pb exposure among both blacks (OR 3.96, 95% CI 1.01–15.46, P = 0.048) and whites (OR 2.95, 95% CI 1.18–7.39, P = 0.020). CONCLUSIONS Genetic variation in ALAD may modify associations between Pb and prostate cancer. Additional studies of ALAD, Pb, and prostate cancer are warranted and should include black men. PMID:24500903

Signatures of α clustering in ultrarelativistic collisions with light nuclei

NASA Astrophysics Data System (ADS)

Rybczyński, Maciej; Piotrowska, Milena; Broniowski, Wojciech

2018-03-01

We explore possible observable signatures of α clustering of light nuclei in ultrarelativistic nuclear collisions involving Be,97, 12C, and 16O. The clustering leads to specific spatial correlations of the nucleon distributions in the ground state, which are manifest in the earliest stage of the ultrahigh energy reaction. The formed initial state of the fireball is sensitive to these correlations, and the effect influences, after the collective evolution of the system, the hadron production in the final stage. Specifically, we study effects on the harmonic flow in collisions of light clustered nuclei with a heavy target (208Pb), showing that measures of the elliptic flow are sensitive to clusterization in Be,97, whereas triangular flow is sensitive to clusterization in 12C and 16O. Specific predictions are made for model collisions at energies available at the CERN Super Proton Synchrotron. In another exploratory development we also examine proton-beryllium collisions, where the 3 /2- ground state of Be,97 nuclei is polarized by an external magnetic field. Clusterization leads to multiplicity distributions of participant nucleons which depend on the orientation of the polarization with respect to the collision axis, as well as on the magnetic number of the state. The obtained effects on multiplicities reach a factor of a few for collisions with a large number of participant nucleons.

22 CFR 208.965 - Legal proceedings.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Legal proceedings. 208.965 Section 208.965 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Definitions § 208.965 Legal proceedings. Legal proceedings means any criminal proceeding or any...

22 CFR 208.965 - Legal proceedings.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Legal proceedings. 208.965 Section 208.965 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Definitions § 208.965 Legal proceedings. Legal proceedings means any criminal proceeding or any...

40 CFR 240.208 - Residue.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Residue. 240.208 Section 240.208 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.208 Residue. ...

5 CFR 430.208 - Rating performance.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Rating performance. 430.208 Section 430.208 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERFORMANCE MANAGEMENT Performance Appraisal for General Schedule, Prevailing Rate, and Certain Other Employees § 430.208...

5 CFR 430.208 - Rating performance.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Rating performance. 430.208 Section 430.208 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERFORMANCE MANAGEMENT Performance Appraisal for General Schedule, Prevailing Rate, and Certain Other Employees § 430.208...

5 CFR 430.208 - Rating performance.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Rating performance. 430.208 Section 430.208 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERFORMANCE MANAGEMENT Performance Appraisal for General Schedule, Prevailing Rate, and Certain Other Employees § 430.208...

5 CFR 430.208 - Rating performance.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Rating performance. 430.208 Section 430.208 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERFORMANCE MANAGEMENT Performance Appraisal for General Schedule, Prevailing Rate, and Certain Other Employees § 430.208...

48 CFR 208.405 - Ordering procedures for Federal Supply Schedules.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Federal Supply Schedules. 208.405 Section 208.405 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE ACQUISITION PLANNING REQUIRED SOURCES OF SUPPLIES AND SERVICES Federal Supply Schedules 208.405 Ordering procedures for Federal Supply Schedules. In all orders...

42 CFR 460.208 - Financial statements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 4 2010-10-01 2010-10-01 false Financial statements. 460.208 Section 460.208... ELDERLY (PACE) Data Collection, Record Maintenance, and Reporting § 460.208 Financial statements. (a... must submit a certified financial statement that includes appropriate footnotes. (2) The financial...

29 CFR 2200.208 - Discovery.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 9 2011-07-01 2011-07-01 false Discovery. 2200.208 Section 2200.208 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH REVIEW COMMISSION RULES OF PROCEDURE Simplified Proceedings § 2200.208 Discovery. Discovery, including requests for admissions, will only be...

29 CFR 2200.208 - Discovery.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 9 2014-07-01 2014-07-01 false Discovery. 2200.208 Section 2200.208 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH REVIEW COMMISSION RULES OF PROCEDURE Simplified Proceedings § 2200.208 Discovery. Discovery, including requests for admissions, will only be...

29 CFR 2200.208 - Discovery.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 9 2012-07-01 2012-07-01 false Discovery. 2200.208 Section 2200.208 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH REVIEW COMMISSION RULES OF PROCEDURE Simplified Proceedings § 2200.208 Discovery. Discovery, including requests for admissions, will only be...

29 CFR 2200.208 - Discovery.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 9 2013-07-01 2013-07-01 false Discovery. 2200.208 Section 2200.208 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH REVIEW COMMISSION RULES OF PROCEDURE Simplified Proceedings § 2200.208 Discovery. Discovery, including requests for admissions, will only be...

29 CFR 2200.208 - Discovery.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false Discovery. 2200.208 Section 2200.208 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH REVIEW COMMISSION RULES OF PROCEDURE Simplified Proceedings § 2200.208 Discovery. Discovery, including requests for admissions, will only be...

18 CFR 706.208 - Indebtedness.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 2 2014-04-01 2014-04-01 false Indebtedness. 706.208 Section 706.208 Conservation of Power and Water Resources WATER RESOURCES COUNCIL EMPLOYEE RESPONSIBILITIES AND CONDUCT Conduct and Responsibilities of Employees § 706.208 Indebtedness. (a) An employee...

18 CFR 706.208 - Indebtedness.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Indebtedness. 706.208 Section 706.208 Conservation of Power and Water Resources WATER RESOURCES COUNCIL EMPLOYEE RESPONSIBILITIES AND CONDUCT Conduct and Responsibilities of Employees § 706.208 Indebtedness. (a) An employee...

18 CFR 706.208 - Indebtedness.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 2 2013-04-01 2012-04-01 true Indebtedness. 706.208 Section 706.208 Conservation of Power and Water Resources WATER RESOURCES COUNCIL EMPLOYEE RESPONSIBILITIES AND CONDUCT Conduct and Responsibilities of Employees § 706.208 Indebtedness. (a) An employee...

18 CFR 706.208 - Indebtedness.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Indebtedness. 706.208 Section 706.208 Conservation of Power and Water Resources WATER RESOURCES COUNCIL EMPLOYEE RESPONSIBILITIES AND CONDUCT Conduct and Responsibilities of Employees § 706.208 Indebtedness. (a) An employee...

ISOTOPIC COMPOSITION OF THE COMMON LEAD OF JAPAN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sakai, H.; Sato, K.

1958-11-01

Lead tetramethyl was synthesized from lead iodide isolated from 14 galenas, 2 anglesites, and 6 pyromorphites of Japan. The mass spectrometric analysis was carried out for the peaks of lead and lead hydride ions. The isotopic compositions of leads from these minerais lie wiyhn a narrow range. The average values for gnlanas are 18.51 O 0.05 for Pb/sup 238//Pb/sup 204/ 15.60 plus or minus 0.05 for Pb/sup 207//Pb/sup 204/8.76 plus or minus 0.15 forPb/ sup 208//Pb/sup 204/ For lead of secondary minerals they are 18.52 plus or minus 0.05, 15.62 plus or minus 0.05, and 38.78 plus or minus 0.15,more » respectively. No detectabla difference was observed between the isotopic compositions of primary and secondary lead ores. The ratios, U/sub 238/Pb/sup 204, and Th/sup 232/ U/sup 238/, in the source magma are estimated from the lead abundances. They are« less

A study of spin isovector giant resonances with the208Pb(n, p)208Tl reaction

NASA Astrophysics Data System (ADS)

Moinester, M. A.; Trudel, A.; Raywood, K.; Yen, S.; Spicer, B. M.; Abegg, R.; Alford, W. P.; Auerbach, N.; Celler, A.; Frekers, D.; Häusser, O.; Helmer, R. L.; Henderson, R.; Hicks, K. H.; Jackson, K. P.; Jeppesen, R. G.; King, N. S. P.; Long, S.; Miller, C. A.; Vetterli, M.; Watson, J.; Yavin, A. I.

1989-10-01

The208Pb(n, p)208Tl reaction was studied at 198 and 458 MeV in a search for isovector spin giant resonances. Peaks at 5.1 MeV and 13.6 MeV excitation in208Tl are observed and discussed as candidates for the T> spin giant dipole resonance (SGDR), the spin isovector monopole resonance (SIVM), and the spin isovector quadrupole resonance (SIVQ).

Lead isotope ratio measurements as indicators for the source of lead poisoning in Mute swans (Cygnus olor) wintering in Puck Bay (northern Poland).

PubMed

Binkowski, Łukasz J; Meissner, Włodzimierz; Trzeciak, Marta; Izevbekhai, Kelvin; Barker, James

2016-12-01

Lead (Pb) poisoning is most commonly linked amongst anthropogenically-caused deaths in waterfowl and this is often associated with hunting and fishing activities. However, the exact identification of the source may be difficult with commonly-used techniques. We have studied isotope ratios using Inductively-Coupled Plasma Mass Spectrometry (ICP-MS) to investigate the source of Pb in the blood of Mute swans (n = 49) wintering in northern Poland. We compared the values of isotopic ratios from blood and ammunition pellets available on the Polish market. The mean Pb concentrations found was 0.241 μg/g (w/w) and nearly half of the blood specimens had elevated Pb levels (higher than the cited 0.23 μg/g w/w threshold of poisoning). Only the mean 208/206 Pb isotope ratio was similar in blood and pellet samples. Mean ratios of isotopes 206/204, 206/207 and 208/207 in swans' blood and in pellets differed significantly. Moreover, coefficients of variation were higher in blood samples than in pellets. These discrepancies and significant differences in abundance of 204 Pb and 207 Pb isotopes in both materials indicated that pellets available today on the Polish market were not the source of Pb in the blood of Mute swans wintering in northern Poland. Copyright © 2016 Elsevier Ltd. All rights reserved.

40 CFR 240.208-1 - Requirement.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirement. 240.208-1 Section 240.208-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.208-1 Requirement...

40 CFR 240.208-1 - Requirement.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirement. 240.208-1 Section 240.208-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.208-1 Requirement...

40 CFR 240.208-1 - Requirement.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirement. 240.208-1 Section 240.208-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.208-1 Requirement...

20 CFR 345.208 - System records.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true System records. 345.208 Section 345.208... EMPLOYERS' CONTRIBUTIONS AND CONTRIBUTION REPORTS Individual Employer Records § 345.208 System records... charges, pooled credits, and unallocated charges for the experience rating system and will publish a...

20 CFR 345.208 - System records.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false System records. 345.208 Section 345.208... EMPLOYERS' CONTRIBUTIONS AND CONTRIBUTION REPORTS Individual Employer Records § 345.208 System records... charges, pooled credits, and unallocated charges for the experience rating system and will publish a...

20 CFR 345.208 - System records.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false System records. 345.208 Section 345.208... EMPLOYERS' CONTRIBUTIONS AND CONTRIBUTION REPORTS Individual Employer Records § 345.208 System records... charges, pooled credits, and unallocated charges for the experience rating system and will publish a...

31 CFR 208.4 - Waivers.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Waivers. 208.4 Section 208.4 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL AGENCY DISBURSEMENTS § 208.4...

31 CFR 208.2 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Definitions. 208.2 Section 208.2 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL AGENCY DISBURSEMENTS § 208.2...

20 CFR 345.208 - System records.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false System records. 345.208 Section 345.208... EMPLOYERS' CONTRIBUTIONS AND CONTRIBUTION REPORTS Individual Employer Records § 345.208 System records... charges, pooled credits, and unallocated charges for the experience rating system and will publish a...

22 CFR 208.995 - Principal.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Principal. 208.995 Section 208.995 Foreign...) Definitions § 208.995 Principal. Principal means— (a) An officer, director, owner, partner, principal investigator, or other person within a participant with management or supervisory responsibilities related to a...

44 CFR 208.35 - Reimbursement for Advisory.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Cooperative Agreements § 208.35 Reimbursement for Advisory. DHS will not reimburse costs incurred during an... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Reimbursement for Advisory. 208.35 Section 208.35 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY...

44 CFR 208.42 - Reimbursement for other administrative costs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Reimbursement for other administrative costs. 208.42 Section 208.42 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT... SYSTEM Response Cooperative Agreements § 208.42 Reimbursement for other administrative costs. Costs...

19 CFR 208.5 - Public hearing.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 3 2010-04-01 2010-04-01 false Public hearing. 208.5 Section 208.5 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS WITH RESPECT TO COMMERCIAL AVAILABILITY OF TEXTILE FABRIC AND YARN IN SUB-SAHARAN AFRICAN COUNTRIES § 208.5 Public...

30 CFR 90.208 - Bimonthly sampling.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Bimonthly sampling. 90.208 Section 90.208... MANDATORY HEALTH STANDARDS-COAL MINERS WHO HAVE EVIDENCE OF THE DEVELOPMENT OF PNEUMOCONIOSIS Sampling Procedures § 90.208 Bimonthly sampling. (a) Each operator shall take one valid respirable dust sample for...

30 CFR 90.208 - Bimonthly sampling.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Bimonthly sampling. 90.208 Section 90.208... MANDATORY HEALTH STANDARDS-COAL MINERS WHO HAVE EVIDENCE OF THE DEVELOPMENT OF PNEUMOCONIOSIS Sampling Procedures § 90.208 Bimonthly sampling. (a) Each operator shall take one valid respirable dust sample for...

23 CFR 633.208 - Maintenance.

Code of Federal Regulations, 2010 CFR

2010-04-01

... responsibility of the State. The State may arrange for maintenance of such roads or portions thereof, by... 23 Highways 1 2010-04-01 2010-04-01 false Maintenance. 633.208 Section 633.208 Highways FEDERAL... PROVISIONS Federal-Aid Contracts (Appalachian Contracts) § 633.208 Maintenance. Maintenance of all highway...

7 CFR 1400.208 - Family members.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Family members. 1400.208 Section 1400.208 Agriculture... SUBSEQUENT CROP, PROGRAM, OR FISCAL YEARS Payment Eligibility § 1400.208 Family members. (a) Notwithstanding... persons, a majority of whom are family members, an adult family member who makes a significant...

34 CFR 685.208 - Repayment plans.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 3 2010-07-01 2010-07-01 false Repayment plans. 685.208 Section 685.208 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION WILLIAM D. FORD FEDERAL DIRECT LOAN PROGRAM Borrower Provisions § 685.208 Repayment...

44 CFR 208.26 - Accountability for use of funds.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Accountability for use of funds. 208.26 Section 208.26 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY... Preparedness Cooperative Agreements § 208.26 Accountability for use of funds. The Sponsoring Agency is...

44 CFR 208.46 - Title to equipment.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Title to equipment. 208.46 Section 208.46 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF... Agreements § 208.46 Title to equipment. Title to equipment purchased by a Sponsoring Agency with funds...

44 CFR 208.27 - Title to equipment.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Title to equipment. 208.27 Section 208.27 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF... Cooperative Agreements § 208.27 Title to equipment. Title to equipment purchased by a Sponsoring Agency with...

9 CFR 93.208 - Articles accompanying poultry.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Articles accompanying poultry. 93.208 Section 93.208 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF... FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Poultry § 93.208 Articles accompanying poultry. No...

9 CFR 93.208 - Articles accompanying poultry.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Articles accompanying poultry. 93.208 Section 93.208 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF... FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Poultry § 93.208 Articles accompanying poultry. No...

9 CFR 93.208 - Articles accompanying poultry.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Articles accompanying poultry. 93.208 Section 93.208 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF... FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Poultry § 93.208 Articles accompanying poultry. No...

9 CFR 93.208 - Articles accompanying poultry.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Articles accompanying poultry. 93.208 Section 93.208 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF... FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Poultry § 93.208 Articles accompanying poultry. No...

9 CFR 93.208 - Articles accompanying poultry.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Articles accompanying poultry. 93.208 Section 93.208 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF... FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Poultry § 93.208 Articles accompanying poultry. No...

50 CFR 226.208 - Critical habitat for green turtle.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 50 Wildlife and Fisheries 10 2012-10-01 2012-10-01 false Critical habitat for green turtle. 226.208 Section 226.208 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS DESIGNATED CRITICAL HABITAT § 226.208...

5 CFR 1216.208 - Restrictions that apply to released records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Restrictions that apply to released records. 1216.208 Section 1216.208 Administrative Personnel MERIT SYSTEMS PROTECTION BOARD ORGANIZATION... RECORDS IN LEGAL PROCEEDINGS Demands or Requests for Testimony and Production of Documents § 1216.208...

48 CFR 208.7003-1 - Assignments under integrated materiel management (IMM).

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Assignments under integrated materiel management (IMM). 208.7003-1 Section 208.7003-1 Federal Acquisition Regulations System... SUPPLIES AND SERVICES Coordinated Acquisition 208.7003-1 Assignments under integrated materiel management...

48 CFR 208.7003-1 - Assignments under integrated materiel management (IMM).

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Assignments under integrated materiel management (IMM). 208.7003-1 Section 208.7003-1 Federal Acquisition Regulations System... SUPPLIES AND SERVICES Coordinated Acquisition 208.7003-1 Assignments under integrated materiel management...

48 CFR 208.7003-1 - Assignments under integrated materiel management (IMM).

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Assignments under integrated materiel management (IMM). 208.7003-1 Section 208.7003-1 Federal Acquisition Regulations System... SUPPLIES AND SERVICES Coordinated Acquisition 208.7003-1 Assignments under integrated materiel management...

48 CFR 208.7003-1 - Assignments under integrated materiel management (IMM).

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Assignments under integrated materiel management (IMM). 208.7003-1 Section 208.7003-1 Federal Acquisition Regulations System... SUPPLIES AND SERVICES Coordinated Acquisition 208.7003-1 Assignments under integrated materiel management...

48 CFR 208.7003-1 - Assignments under integrated materiel management (IMM).

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Assignments under integrated materiel management (IMM). 208.7003-1 Section 208.7003-1 Federal Acquisition Regulations System... SUPPLIES AND SERVICES Coordinated Acquisition 208.7003-1 Assignments under integrated materiel management...

48 CFR 1817.208 - Solicitation provisions and contract clauses. (NASA supplements paragraph (c))

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Solicitation provisions and contract clauses. (NASA supplements paragraph (c)) 1817.208 Section 1817.208 Federal Acquisition... SPECIAL CONTRACTING METHODS Options 1817.208 Solicitation provisions and contract clauses. (NASA...

48 CFR 1817.208 - Solicitation provisions and contract clauses. (NASA supplements paragraph (c))

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Solicitation provisions and contract clauses. (NASA supplements paragraph (c)) 1817.208 Section 1817.208 Federal Acquisition... SPECIAL CONTRACTING METHODS Options 1817.208 Solicitation provisions and contract clauses. (NASA...

46 CFR 185.208 - Accidents to machinery.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 7 2011-10-01 2011-10-01 false Accidents to machinery. 185.208 Section 185.208 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Marine Casualties and Voyage Records § 185.208 Accidents to machinery. The owner, managing...

46 CFR 185.208 - Accidents to machinery.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Accidents to machinery. 185.208 Section 185.208 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Marine Casualties and Voyage Records § 185.208 Accidents to machinery. The owner, managing...

22 CFR 208.510 - Who maintains the EPLS?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Who maintains the EPLS? 208.510 Section 208.510 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Excluded Parties List System § 208.510 Who maintains the EPLS? In accordance with the OMB...

22 CFR 208.510 - Who maintains the EPLS?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Who maintains the EPLS? 208.510 Section 208.510 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Excluded Parties List System § 208.510 Who maintains the EPLS? In accordance with the OMB...

28 CFR 16.208 - Annual report.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Annual report. 16.208 Section 16.208... Observation of Parole Commission Meetings § 16.208 Annual report. The Commission shall report annually to Congress regarding its compliance with Sunshine Act requirements, including a tabulation of the total...

28 CFR 16.208 - Annual report.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Annual report. 16.208 Section 16.208... Observation of Parole Commission Meetings § 16.208 Annual report. The Commission shall report annually to Congress regarding its compliance with Sunshine Act requirements, including a tabulation of the total...

28 CFR 16.208 - Annual report.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Annual report. 16.208 Section 16.208... Observation of Parole Commission Meetings § 16.208 Annual report. The Commission shall report annually to Congress regarding its compliance with Sunshine Act requirements, including a tabulation of the total...

28 CFR 16.208 - Annual report.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Annual report. 16.208 Section 16.208... Observation of Parole Commission Meetings § 16.208 Annual report. The Commission shall report annually to Congress regarding its compliance with Sunshine Act requirements, including a tabulation of the total...

7 CFR 1400.208 - Family members.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Family members. 1400.208 Section 1400.208 Agriculture... SUBSEQUENT CROP, PROGRAM, OR FISCAL YEARS Payment Eligibility § 1400.208 Family members. (a) Notwithstanding... persons, a majority of whom are family members, an adult family member who makes a significant...

8 CFR 208.2 - Jurisdiction

Code of Federal Regulations, 2010 CFR

2010-01-01

... jurisdiction over credible fear determinations under § 208.30 and reasonable fear determinations under § 208.31... reasonable fear determinations referred to the Immigration Court under § 208.31, and credible fear... longer than authorized; (ii) An alien stowaway who has been found to have a credible fear of persecution...

23 CFR 646.208 - Funding.

Code of Federal Regulations, 2010 CFR

2010-04-01

...-Highway Projects § 646.208 Funding. (a) Railroad/highway crossing projects may be funded through the Federal-aid funding source appropriate for the involved project. (b) Projects for the elimination of... 23 Highways 1 2010-04-01 2010-04-01 false Funding. 646.208 Section 646.208 Highways FEDERAL...

10 CFR 1015.208 - Administrative wage garnishment.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Administrative wage garnishment. 1015.208 Section 1015.208... for the Administrative Collection of Claims § 1015.208 Administrative wage garnishment. (a) DOE may use administrative wage garnishment to collect money from a debtor's disposable pay to satisfy...

48 CFR 208.7005 - Military interdepartmental purchase requests.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Military interdepartmental... Coordinated Acquisition 208.7005 Military interdepartmental purchase requests. Follow the procedures at— (a) PGI 253.208-1 when using DD Form 448, Military Interdepartmental Purchase Request; and (b) PGI 253.208...

23 CFR 646.208 - Funding.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 23 Highways 1 2014-04-01 2014-04-01 false Funding. 646.208 Section 646.208 Highways FEDERAL...-Highway Projects § 646.208 Funding. (a) Railroad/highway crossing projects may be funded through the Federal-aid funding source appropriate for the involved project. (b) Projects for the elimination of...

23 CFR 646.208 - Funding.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 23 Highways 1 2013-04-01 2013-04-01 false Funding. 646.208 Section 646.208 Highways FEDERAL...-Highway Projects § 646.208 Funding. (a) Railroad/highway crossing projects may be funded through the Federal-aid funding source appropriate for the involved project. (b) Projects for the elimination of...

23 CFR 646.208 - Funding.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false Funding. 646.208 Section 646.208 Highways FEDERAL...-Highway Projects § 646.208 Funding. (a) Railroad/highway crossing projects may be funded through the Federal-aid funding source appropriate for the involved project. (b) Projects for the elimination of...

23 CFR 646.208 - Funding.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 23 Highways 1 2012-04-01 2012-04-01 false Funding. 646.208 Section 646.208 Highways FEDERAL...-Highway Projects § 646.208 Funding. (a) Railroad/highway crossing projects may be funded through the Federal-aid funding source appropriate for the involved project. (b) Projects for the elimination of...

19 CFR 208.1 - Applicability of part.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 3 2010-04-01 2010-04-01 false Applicability of part. 208.1 Section 208.1 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS WITH RESPECT TO COMMERCIAL AVAILABILITY OF TEXTILE FABRIC AND YARN IN SUB-SAHARAN AFRICAN COUNTRIES § 208.1...

44 CFR 208.36 - Reimbursement for Alert.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Reimbursement for Alert. 208.36 Section 208.36 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT... § 208.41 of this part. (4) Food and beverages for Task Force Members and Support Specialists when DHS...

31 CFR 208.1 - Scope and application.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Scope and application. 208.1 Section 208.1 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL AGENCY DISBURSEMENTS § 208.1...

20 CFR 498.208 - Exchange of witness lists, witness statements and exhibits.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Exchange of witness lists, witness statements and exhibits. 498.208 Section 498.208 Employees' Benefits SOCIAL SECURITY ADMINISTRATION CIVIL MONETARY PENALTIES, ASSESSMENTS AND RECOMMENDED EXCLUSIONS § 498.208 Exchange of witness lists, witness...

48 CFR 52.208-5 - Condition of Leased Vehicles.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Vehicles. 52.208-5 Section 52.208-5 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION....208-5 Condition of Leased Vehicles. As prescribed in 8.1104(b), insert the following clause in solicitations and contracts for leasing motor vehicles, unless the motor vehicles are leased in foreign...

29 CFR 825.208 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 3 2012-07-01 2012-07-01 false [Reserved] 825.208 Section 825.208 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee Leave Entitlements Under the Family and Medical Leave Act § 825.208 [Reserved] ...

29 CFR 825.208 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 3 2013-07-01 2013-07-01 false [Reserved] 825.208 Section 825.208 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee Leave Entitlements Under the Family and Medical Leave Act § 825.208 [Reserved] ...

29 CFR 825.208 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 3 2014-07-01 2014-07-01 false [Reserved] 825.208 Section 825.208 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee Leave Entitlements Under the Family and Medical Leave Act § 825.208 [Reserved] ...

29 CFR 825.208 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 3 2011-07-01 2011-07-01 false [Reserved] 825.208 Section 825.208 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee Leave Entitlements Under the Family and Medical Leave Act § 825.208 [Reserved] ...

29 CFR 825.208 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false [Reserved] 825.208 Section 825.208 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee Leave Entitlements Under the Family and Medical Leave Act § 825.208 [Reserved] ...

12 CFR 208.63 - Procedures for monitoring Bank Secrecy Act compliance.

Code of Federal Regulations, 2010 CFR

2010-01-01

... compliance. 208.63 Section 208.63 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM MEMBERSHIP OF STATE BANKING INSTITUTIONS IN THE FEDERAL RESERVE SYSTEM (REGULATION H) Miscellaneous Requirements § 208.63 Procedures for monitoring Bank Secrecy Act compliance. (a) Purpose. This...

12 CFR 208.60 - Authority, purpose, and scope.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 208.60 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM MEMBERSHIP OF STATE BANKING INSTITUTIONS IN THE FEDERAL RESERVE SYSTEM (REGULATION H) Miscellaneous Requirements § 208.60 Authority, purpose, and scope. (a) Authority. Subpart F of Regulation H (12 CFR part 208...

33 CFR 110.208 - Buffalo Harbor, N.Y.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Buffalo Harbor, N.Y. 110.208 Section 110.208 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.208 Buffalo Harbor, N.Y. (a) The anchorage grounds—(1...

50 CFR 226.208 - Critical habitat for green turtle.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Critical habitat for green turtle. 226.208 Section 226.208 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS DESIGNATED CRITICAL HABITAT § 226.208 Critical habitat for...

49 CFR 195.208 - Welding of supports and braces.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 3 2010-10-01 2010-10-01 false Welding of supports and braces. 195.208 Section 195.208 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS... HAZARDOUS LIQUIDS BY PIPELINE Construction § 195.208 Welding of supports and braces. Supports or braces may...

18 CFR 376.208 - Effect upon existing Commission requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Effect upon existing Commission requirements. 376.208 Section 376.208 Conservation of Power and Water Resources FEDERAL ENERGY...; OPERATIONS DURING EMERGENCY CONDITIONS Commission Operation During Emergency Conditions § 376.208 Effect upon...

18 CFR 376.208 - Effect upon existing Commission requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Effect upon existing Commission requirements. 376.208 Section 376.208 Conservation of Power and Water Resources FEDERAL ENERGY...; OPERATIONS DURING EMERGENCY CONDITIONS Commission Operation During Emergency Conditions § 376.208 Effect upon...

18 CFR 376.208 - Effect upon existing Commission requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Effect upon existing Commission requirements. 376.208 Section 376.208 Conservation of Power and Water Resources FEDERAL ENERGY...; OPERATIONS DURING EMERGENCY CONDITIONS Commission Operation During Emergency Conditions § 376.208 Effect upon...

18 CFR 376.208 - Effect upon existing Commission requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Effect upon existing Commission requirements. 376.208 Section 376.208 Conservation of Power and Water Resources FEDERAL ENERGY...; OPERATIONS DURING EMERGENCY CONDITIONS Commission Operation During Emergency Conditions § 376.208 Effect upon...

18 CFR 376.208 - Effect upon existing Commission requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Effect upon existing Commission requirements. 376.208 Section 376.208 Conservation of Power and Water Resources FEDERAL ENERGY...; OPERATIONS DURING EMERGENCY CONDITIONS Commission Operation During Emergency Conditions § 376.208 Effect upon...

12 CFR 208.61 - Bank security procedures.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 2 2011-01-01 2011-01-01 false Bank security procedures. 208.61 Section 208.61 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM MEMBERSHIP OF STATE BANKING INSTITUTIONS IN THE FEDERAL RESERVE SYSTEM (REGULATION H) Miscellaneous Requirements § 208...

46 CFR 122.208 - Accidents to machinery.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Accidents to machinery. 122.208 Section 122.208 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS CARRYING MORE THAN 150... Voyage Records § 122.208 Accidents to machinery. The owner, managing operator, or master shall report...

46 CFR 122.208 - Accidents to machinery.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Accidents to machinery. 122.208 Section 122.208 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS CARRYING MORE THAN 150... Voyage Records § 122.208 Accidents to machinery. The owner, managing operator, or master shall report...

30 CFR 208.9 - Agreements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Agreements. 208.9 Section 208.9 Mineral... FEDERAL ROYALTY OIL General Provisions § 208.9 Agreements. (a) A purchaser must submit to MMS two copies of any written third-party agreements, or two copies of a full written explanation of any oral third...

31 CFR 535.208 - Evasions; effective date.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Evasions; effective date. 535.208 Section 535.208 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE... § 535.208 Evasions; effective date. (a) Any transaction for the purpose of, or which has the effect of...

30 CFR 208.15 - Audits.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Audits. 208.15 Section 208.15 Mineral Resources... OIL General Provisions § 208.15 Audits. Audits of the accounts and books of lessees, operators, payors... directed by MMS. Such audits will be for the purpose of determining compliance with applicable statutes...

30 CFR 75.208 - Warning devices.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Warning devices. 75.208 Section 75.208 Mineral... SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.208 Warning devices. Except during the installation of roof supports, the end of permanent roof support shall be posted with a readily visible warning...

30 CFR 75.208 - Warning devices.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Warning devices. 75.208 Section 75.208 Mineral... SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.208 Warning devices. Except during the installation of roof supports, the end of permanent roof support shall be posted with a readily visible warning...

30 CFR 75.208 - Warning devices.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Warning devices. 75.208 Section 75.208 Mineral... SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.208 Warning devices. Except during the installation of roof supports, the end of permanent roof support shall be posted with a readily visible warning...

30 CFR 75.208 - Warning devices.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Warning devices. 75.208 Section 75.208 Mineral... SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.208 Warning devices. Except during the installation of roof supports, the end of permanent roof support shall be posted with a readily visible warning...

30 CFR 75.208 - Warning devices.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Warning devices. 75.208 Section 75.208 Mineral... SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.208 Warning devices. Except during the installation of roof supports, the end of permanent roof support shall be posted with a readily visible warning...

48 CFR 1815.208 - Submission, modification, revision, and withdrawal of proposals. (NASA supplements paragraph (b))

Code of Federal Regulations, 2012 CFR

2012-10-01

..., revision, and withdrawal of proposals. (NASA supplements paragraph (b)) 1815.208 Section 1815.208 Federal... TYPES CONTRACTING BY NEGOTIATION Solicitation and Receipt of Proposals and Information 1815.208 Submission, modification, revision, and withdrawal of proposals. (NASA supplements paragraph (b)) (b) The FAR...

48 CFR 1815.208 - Submission, modification, revision, and withdrawal of proposals. (NASA supplements paragraph (b))

Code of Federal Regulations, 2011 CFR

2011-10-01

..., revision, and withdrawal of proposals. (NASA supplements paragraph (b)) 1815.208 Section 1815.208 Federal... TYPES CONTRACTING BY NEGOTIATION Solicitation and Receipt of Proposals and Information 1815.208 Submission, modification, revision, and withdrawal of proposals. (NASA supplements paragraph (b)) (b) The FAR...

48 CFR 1815.208 - Submission, modification, revision, and withdrawal of proposals. (NASA supplements paragraph (b))

Code of Federal Regulations, 2013 CFR

2013-10-01

..., revision, and withdrawal of proposals. (NASA supplements paragraph (b)) 1815.208 Section 1815.208 Federal... TYPES CONTRACTING BY NEGOTIATION Solicitation and Receipt of Proposals and Information 1815.208 Submission, modification, revision, and withdrawal of proposals. (NASA supplements paragraph (b)) (b) The FAR...

48 CFR 1815.208 - Submission, modification, revision, and withdrawal of proposals. (NASA supplements paragraph (b))

Code of Federal Regulations, 2014 CFR

2014-10-01

..., revision, and withdrawal of proposals. (NASA supplements paragraph (b)) 1815.208 Section 1815.208 Federal... TYPES CONTRACTING BY NEGOTIATION Solicitation and Receipt of Proposals and Information 1815.208 Submission, modification, revision, and withdrawal of proposals. (NASA supplements paragraph (b)) (b) The FAR...

44 CFR 208.64 - Administrative and audit requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Administrative and audit requirements. 208.64 Section 208.64 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE NATIONAL URBAN SEARCH AND RESCUE RESPONSE SYSTEM Reimbursement Claims and Appeals § 208.64...

30 CFR 77.208 - Storage of materials.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Storage of materials. 77.208 Section 77.208 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH... Installations § 77.208 Storage of materials. (a) Materials shall be stored and stacked in a manner which...

30 CFR 77.208 - Storage of materials.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Storage of materials. 77.208 Section 77.208 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH... Installations § 77.208 Storage of materials. (a) Materials shall be stored and stacked in a manner which...

5 CFR 842.208 - Firefighters, law enforcement officers, and nuclear materials couriers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Firefighters, law enforcement officers, and nuclear materials couriers. 842.208 Section 842.208 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES RETIREMENT SYSTEM-BASIC ANNUITY Eligibility § 842.208 Firefighters, la...

33 CFR 110.208 - Buffalo Harbor, N.Y.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Buffalo Harbor, N.Y. 110.208 Section 110.208 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.208 Buffalo Harbor, N.Y. (a) The anchorage grounds—(1...

18 CFR 701.208 - WRC petition for judicial extension of time.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 2 2012-04-01 2012-04-01 false WRC petition for judicial extension of time. 701.208 Section 701.208 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COUNCIL ORGANIZATION Availability of Information § 701.208 WRC petition for judicial...

18 CFR 701.208 - WRC petition for judicial extension of time.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false WRC petition for judicial extension of time. 701.208 Section 701.208 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COUNCIL ORGANIZATION Availability of Information § 701.208 WRC petition for judicial...

18 CFR 701.208 - WRC petition for judicial extension of time.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 2 2013-04-01 2012-04-01 true WRC petition for judicial extension of time. 701.208 Section 701.208 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COUNCIL ORGANIZATION Availability of Information § 701.208 WRC petition for judicial...

18 CFR 701.208 - WRC petition for judicial extension of time.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 2 2014-04-01 2014-04-01 false WRC petition for judicial extension of time. 701.208 Section 701.208 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COUNCIL ORGANIZATION Availability of Information § 701.208 WRC petition for judicial...

18 CFR 701.208 - WRC petition for judicial extension of time.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false WRC petition for judicial extension of time. 701.208 Section 701.208 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COUNCIL ORGANIZATION Availability of Information § 701.208 WRC petition for judicial...

44 CFR 208.3 - Authority for the National US&R Response System.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Order 12148. (b) Implementing plan. The National Response Plan identifies DHS as the primary Federal...&R Response System. 208.3 Section 208.3 Emergency Management and Assistance FEDERAL EMERGENCY... RESPONSE SYSTEM General § 208.3 Authority for the National US&R Response System. (a) Enabling legislation...

44 CFR 208.3 - Authority for the National US&R Response System.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Order 12148. (b) Implementing plan. The National Response Plan identifies DHS as the primary Federal...&R Response System. 208.3 Section 208.3 Emergency Management and Assistance FEDERAL EMERGENCY... RESPONSE SYSTEM General § 208.3 Authority for the National US&R Response System. (a) Enabling legislation...

44 CFR 208.3 - Authority for the National US&R Response System.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Order 12148. (b) Implementing plan. The National Response Plan identifies DHS as the primary Federal...&R Response System. 208.3 Section 208.3 Emergency Management and Assistance FEDERAL EMERGENCY... RESPONSE SYSTEM General § 208.3 Authority for the National US&R Response System. (a) Enabling legislation...

44 CFR 208.3 - Authority for the National US&R Response System.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Order 12148. (b) Implementing plan. The National Response Plan identifies DHS as the primary Federal...&R Response System. 208.3 Section 208.3 Emergency Management and Assistance FEDERAL EMERGENCY... RESPONSE SYSTEM General § 208.3 Authority for the National US&R Response System. (a) Enabling legislation...

44 CFR 208.3 - Authority for the National US&R Response System.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Order 12148. (b) Implementing plan. The National Response Plan identifies DHS as the primary Federal...&R Response System. 208.3 Section 208.3 Emergency Management and Assistance FEDERAL EMERGENCY... RESPONSE SYSTEM General § 208.3 Authority for the National US&R Response System. (a) Enabling legislation...

5 CFR 842.208 - Firefighters, law enforcement officers, and nuclear materials couriers.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., and nuclear materials couriers. 842.208 Section 842.208 Administrative Personnel OFFICE OF PERSONNEL... ANNUITY Eligibility § 842.208 Firefighters, law enforcement officers, and nuclear materials couriers. (a... enforcement officer or nuclear materials courier totaling 25 years; or (2) After becoming age 50 and...

49 CFR 195.208 - Welding of supports and braces.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 3 2012-10-01 2012-10-01 false Welding of supports and braces. 195.208 Section 195.208 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS... HAZARDOUS LIQUIDS BY PIPELINE Construction § 195.208 Welding of supports and braces. Supports or braces may...

49 CFR 195.208 - Welding of supports and braces.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 3 2011-10-01 2011-10-01 false Welding of supports and braces. 195.208 Section 195.208 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS... HAZARDOUS LIQUIDS BY PIPELINE Construction § 195.208 Welding of supports and braces. Supports or braces may...

49 CFR 195.208 - Welding of supports and braces.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 3 2014-10-01 2014-10-01 false Welding of supports and braces. 195.208 Section 195.208 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS... HAZARDOUS LIQUIDS BY PIPELINE Construction § 195.208 Welding of supports and braces. Supports or braces may...

49 CFR 195.208 - Welding of supports and braces.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 3 2013-10-01 2013-10-01 false Welding of supports and braces. 195.208 Section 195.208 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS... HAZARDOUS LIQUIDS BY PIPELINE Construction § 195.208 Welding of supports and braces. Supports or braces may...

44 CFR 208.6 - System resource reports.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false System resource reports. 208.6 Section 208.6 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE NATIONAL URBAN SEARCH AND RESCUE RESPONSE SYSTEM General § 208.6 System resource reports. (a) Reports to...

7 CFR 20.8 - Failure to report.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 1 2014-01-01 2014-01-01 false Failure to report. 20.8 Section 20.8 Agriculture Office of the Secretary of Agriculture EXPORT SALES REPORTING REQUIREMENTS § 20.8 Failure to report. Any person who knowingly fails to report export sales pursuant to the requirements of these regulations shall...

7 CFR 20.8 - Failure to report.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 1 2010-01-01 2010-01-01 false Failure to report. 20.8 Section 20.8 Agriculture Office of the Secretary of Agriculture EXPORT SALES REPORTING REQUIREMENTS § 20.8 Failure to report. Any person who knowingly fails to report export sales pursuant to the requirements of these regulations shall...

7 CFR 20.8 - Failure to report.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 1 2011-01-01 2011-01-01 false Failure to report. 20.8 Section 20.8 Agriculture Office of the Secretary of Agriculture EXPORT SALES REPORTING REQUIREMENTS § 20.8 Failure to report. Any person who knowingly fails to report export sales pursuant to the requirements of these regulations shall...

7 CFR 20.8 - Failure to report.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 1 2013-01-01 2013-01-01 false Failure to report. 20.8 Section 20.8 Agriculture Office of the Secretary of Agriculture EXPORT SALES REPORTING REQUIREMENTS § 20.8 Failure to report. Any person who knowingly fails to report export sales pursuant to the requirements of these regulations shall...

7 CFR 20.8 - Failure to report.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 1 2012-01-01 2012-01-01 false Failure to report. 20.8 Section 20.8 Agriculture Office of the Secretary of Agriculture EXPORT SALES REPORTING REQUIREMENTS § 20.8 Failure to report. Any person who knowingly fails to report export sales pursuant to the requirements of these regulations shall...

13 CFR 400.208 - Issuance of the Guarantee.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 13 Business Credit and Assistance 1 2014-01-01 2014-01-01 false Issuance of the Guarantee. 400.208 Section 400.208 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.208 Issuance of the Guarantee. (a) The Board's decisions...

13 CFR 400.208 - Issuance of the Guarantee.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Issuance of the Guarantee. 400.208 Section 400.208 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.208 Issuance of the Guarantee. (a) The Board's decisions...

13 CFR 400.208 - Issuance of the Guarantee.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false Issuance of the Guarantee. 400.208 Section 400.208 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.208 Issuance of the Guarantee. (a) The Board's decisions...

13 CFR 400.208 - Issuance of the Guarantee.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false Issuance of the Guarantee. 400.208 Section 400.208 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.208 Issuance of the Guarantee. (a) The Board's decisions...

13 CFR 400.208 - Issuance of the Guarantee.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 13 Business Credit and Assistance 1 2012-01-01 2012-01-01 false Issuance of the Guarantee. 400.208 Section 400.208 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.208 Issuance of the Guarantee. (a) The Board's decisions...

31 CFR 515.208 - Restrictions on loans, credits and other financing.

Code of Federal Regulations, 2010 CFR

2010-07-01

... other financing. 515.208 Section 515.208 Money and Finance: Treasury Regulations Relating to Money and... REGULATIONS Prohibitions § 515.208 Restrictions on loans, credits and other financing. No United States... provide other financing for the purpose of financing transactions involving confiscated property the claim...

Levels and source apportionment of children's lead exposure: could urinary lead be used to identify the levels and sources of children's lead pollution?

PubMed

Cao, Suzhen; Duan, Xiaoli; Zhao, Xiuge; Wang, Beibei; Ma, Jin; Fan, Delong; Sun, Chengye; He, Bin; Wei, Fusheng; Jiang, Guibin

2015-04-01

As a highly toxic heavy metal, the pollution and exposure risks of lead are of widespread concern for human health. However, the collection of blood samples for use as an indicator of lead pollution is not always feasible in most cohort or longitudinal studies, especially those involving children health. To evaluate the potential use of urinary lead as an indicator of exposure levels and source apportionment, accompanying with environmental media samples, lead concentrations and isotopic measurements (expressed as (207)Pb/(206)Pb, (208)Pb/(206)Pb and (204)Pb/(206)Pb) were investigated and compared between blood and urine from children living in the vicinities of a typical coking plant and lead-acid battery factory. The results showed urinary lead might not be a preferable proxy for estimating blood lead levels. Fortunately, urinary lead isotopic measurements could be used as an alternative for identifying the sources of children's lead exposure, which coincided well with the blood lead isotope ratio analysis. Copyright © 2015 Elsevier Ltd. All rights reserved.

Growth Recovery of Lemna gibba and Lemna minor Following a 7-Day Exposure to the Herbicide Diuron.

PubMed

Burns, Mitchell; Hanson, Mark L; Prosser, Ryan S; Crossan, Angus N; Kennedy, Ivan R

2015-08-01

In agricultural catchments, aquatic ecosystems can experience a pulse exposure to pesticides. Following such exposure, non-target organisms that are not extirpated may recover. This paper investigates the potential of two duckweed species (Lemna minor and Lemna gibba) to recover from a 7-day exposure to different concentrations (0.4-208 µg L(-1)) of the herbicide diuron. There was significant inhibition in the growth and biomass after the initial 7-day exposure (e.g. frond number EC50=59.2 and 52.2 µg L(-1) for L. minor and L. gibba, respectively). Following transfer to clean media, recovery (the highest concentration yielding no significant difference in the effect endpoint from the control) was observed for all effects endpoints at concentrations ranging 60-111 µg L(-1) for L. minor and 60-208 µg L(-1) for L. gibba. These results suggest that recovery is possible for primary producers at environmentally relevant concentrations considered significant in ecological risk assessment.

Low-power lead-cooled fast reactor loaded with MOX-fuel

NASA Astrophysics Data System (ADS)

Sitdikov, E. R.; Terekhova, A. M.

2017-01-01

Fast reactor for the purpose of implementation of research, education of undergraduate and doctoral students in handling innovative fast reactors and training specialists for atomic research centers and nuclear power plants (BRUTs) was considered. Hard neutron spectrum achieved in the fast reactor with compact core and lead coolant. Possibility of prompt neutron runaway of the reactor is excluded due to the low reactivity margin which is less than the effective fraction of delayed neutrons. The possibility of using MOX fuel in the BRUTs reactor was examined. The effect of Keff growth connected with replacement of natural lead coolant to 208Pb coolant was evaluated. The calculations and reactor core model were performed using the Serpent Monte Carlo code.

12 CFR 208.76 - What Federal Reserve approvals are necessary for financial subsidiaries?

Code of Federal Regulations, 2010 CFR

2010-01-01

... for financial subsidiaries? 208.76 Section 208.76 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF... SYSTEM (REGULATION H) Financial Subsidiaries of State Member Banks § 208.76 What Federal Reserve approvals are necessary for financial subsidiaries? (a) Notice requirements. (1) A state member bank may not...

22 CFR 208.1005 - State.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false State. 208.1005 Section 208.1005 Foreign...) Definitions § 208.1005 State. (a) State means— (1) Any of the states of the United States; (2) The District of Columbia; (3) The Commonwealth of Puerto Rico; (4) Any territory or possession of the United States; or (5...

22 CFR 208.530 - Where can I find the EPLS?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Where can I find the EPLS? 208.530 Section 208.530 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Excluded Parties List System § 208.530 Where can I find the EPLS? (a) You may access the EPLS...

31 CFR 208.6 - Availability of the Direct Express® Card.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 2 2012-07-01 2012-07-01 false Availability of the Direct Express® Card. 208.6 Section 208.6 Money and Finance: Treasury Regulations Relating to Money and Finance... within the meaning of Public Law 104-208. [75 FR 80335, Dec. 22, 2010] ...

31 CFR 208.6 - Availability of the Direct Express ® Card.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 2 2013-07-01 2013-07-01 false Availability of the Direct Express ® Card. 208.6 Section 208.6 Money and Finance: Treasury Regulations Relating to Money and Finance... within the meaning of Public Law 104-208. [75 FR 80335, Dec. 22, 2010] ...

31 CFR 208.6 - Availability of the Direct Express ® Card.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance: Treasury 2 2014-07-01 2014-07-01 false Availability of the Direct Express ® Card. 208.6 Section 208.6 Money and Finance: Treasury Regulations Relating to Money and Finance... within the meaning of Public Law 104-208. [75 FR 80335, Dec. 22, 2010] ...

42 CFR 59.208 - Use of project funds.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Use of project funds. 59.208 Section 59.208 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Grants for Family Planning Service Training § 59.208 Use of project funds. (a) Any funds granted...

42 CFR 59.208 - Use of project funds.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Use of project funds. 59.208 Section 59.208 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Grants for Family Planning Service Training § 59.208 Use of project funds. (a) Any funds granted...

42 CFR 59.208 - Use of project funds.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Use of project funds. 59.208 Section 59.208 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Grants for Family Planning Service Training § 59.208 Use of project funds. (a) Any funds granted...

42 CFR 59.208 - Use of project funds.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Use of project funds. 59.208 Section 59.208 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Grants for Family Planning Service Training § 59.208 Use of project funds. (a) Any funds granted...

42 CFR 59.208 - Use of project funds.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Use of project funds. 59.208 Section 59.208 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Grants for Family Planning Service Training § 59.208 Use of project funds. (a) Any funds granted...

22 CFR 208.330 - What requirements must I pass down to persons at lower tiers with whom I intend to do business?

Code of Federal Regulations, 2011 CFR

2011-04-01

... at lower tiers with whom I intend to do business? 208.330 Section 208.330 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Responsibilities of Participants Regarding Transactions Doing Business with Other Persons § 208.330 What...

34 CFR 682.208 - Due diligence in servicing a loan.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 3 2010-07-01 2010-07-01 false Due diligence in servicing a loan. 682.208 Section 682.208 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF... § 682.208 Due diligence in servicing a loan. (a) The loan servicing process includes reporting to...

40 CFR 141.208 - Special notice for exceedance of the SMCL for fluoride.

Code of Federal Regulations, 2011 CFR

2011-07-01

... SMCL for fluoride. 141.208 Section 141.208 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Drinking Water Violations § 141.208 Special notice for exceedance of the SMCL for fluoride. (a) When is the special notice to be given? Community water systems that exceed the fluoride secondary maximum contaminant...

40 CFR 141.208 - Special notice for exceedance of the SMCL for fluoride.

Code of Federal Regulations, 2010 CFR

2010-07-01

... SMCL for fluoride. 141.208 Section 141.208 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Drinking Water Violations § 141.208 Special notice for exceedance of the SMCL for fluoride. (a) When is the special notice to be given? Community water systems that exceed the fluoride secondary maximum contaminant...

22 CFR 208.330 - What requirements must I pass down to persons at lower tiers with whom I intend to do business?

Code of Federal Regulations, 2010 CFR

2010-04-01

... at lower tiers with whom I intend to do business? 208.330 Section 208.330 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Responsibilities of Participants Regarding Transactions Doing Business with Other Persons § 208.330 What...

48 CFR 253.208-1 - DD Form 448, Military Interdepartmental Purchase Request.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false DD Form 448, Military Interdepartmental Purchase Request. 253.208-1 Section 253.208-1 Federal Acquisition Regulations System DEFENSE... DD Form 448, Military Interdepartmental Purchase Request. Follow the procedures at PGI 253.208-1 for...

22 CFR 20.8 - Effect on other benefits.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Effect on other benefits. 20.8 Section 20.8 Foreign Relations DEPARTMENT OF STATE PERSONNEL BENEFITS FOR CERTAIN FORMER SPOUSES § 20.8 Effect on other benefits. Payment to a former spouse under this part shall not impair, reduce, or otherwise affect benefits...

7 CFR 760.208 - Availability of funds.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 7 2011-01-01 2011-01-01 false Availability of funds. 760.208 Section 760.208... Farm-Raised Fish Program § 760.208 Availability of funds. By law, “up to” $50 million per year for the... funds that will be considered available to pay claims will be that amount approved by the Secretary...

7 CFR 760.208 - Availability of funds.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 7 2010-01-01 2010-01-01 false Availability of funds. 760.208 Section 760.208... Farm-Raised Fish Program § 760.208 Availability of funds. By law, “up to” $50 million per year for the... funds that will be considered available to pay claims will be that amount approved by the Secretary...

22 CFR 208.920 - Civil judgment.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Civil judgment. 208.920 Section 208.920 Foreign...) Definitions § 208.920 Civil judgment. Civil judgment means the disposition of a civil action by any court of... creates a civil liability for the complained of wrongful acts, or a final determination of liability under...

22 CFR 208.920 - Civil judgment.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Civil judgment. 208.920 Section 208.920 Foreign...) Definitions § 208.920 Civil judgment. Civil judgment means the disposition of a civil action by any court of... creates a civil liability for the complained of wrongful acts, or a final determination of liability under...

12 CFR 208.84 - What you must disclose.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 2 2013-01-01 2013-01-01 false What you must disclose. 208.84 Section 208.84 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM MEMBERSHIP OF... Insurance § 208.84 What you must disclose. (a) Insurance disclosures. In connection with the initial...

Circulating Plasma MicroRNA-208a as Potential Biomarker of Chronic Indeterminate Phase of Chagas Disease.

PubMed

Linhares-Lacerda, Leandra; Granato, Alessandra; Gomes-Neto, João Francisco; Conde, Luciana; Freire-de-Lima, Leonardo; de Freitas, Elisangela O; Freire-de-Lima, Celio G; Coutinho Barroso, Shana P; Jorge de Alcântara Guerra, Rodrigo; Pedrosa, Roberto C; Savino, Wilson; Morrot, Alexandre

2018-01-01

Chagas cardiomyopathy is the most severe clinical manifestation of chronic Chagas disease. The disease affects most of the Latin American countries, being considered one of the leading causes of morbidity and death in the continent. The pathogenesis of Chagas cardiomyopathy is very complex, with mechanisms involving parasite-dependent cytopathy, immune-mediated myocardial damage and neurogenic disturbances. These pathological changes eventually result in cardiac myocyte hypertrophy, arrhythmias, congestive heart failure and stroke during chronic infection phase. Herein, we show that miR-208a, a microRNA that is a key factor in promoting cardiovascular dysfunction during cardiac hypertrophy processes of heart failure, has its circulating levels increased during chronic indeterminate phase when compared to cardiac (CARD) clinical forms in patients with Chagas disease. In contrast, we have not found altered serum levels of miR-34a, a microRNA known to promote pro-apoptotic role in myocardial infarction during degenerative process of cardiac injuries thus indicating intrinsic differences in the nature of the mechanisms underlying the heart failure triggered by Trypanosoma cruzi infection. Our findings support that the chronic indeterminate phase is a progressive phase involved in the genesis of chagasic cardiopathy and point out the use of plasma levels of miR-208a as candidate biomarker in risk-prediction score for the clinical prognosis of Chagas disease.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Monna, F.; Aiuppa, A.; Varrica, D.

A total of 25 lichen thalli of Parmelia conspersa (Ehrh), collected at Vulcano island and at Mt. Etna, during a one-year biogeochemical survey, were analyzed for Pb, br, Al, Sc,[sup 206]Pb/[sup 207]Pb, and [sup 208]Pb/[sup 206]Pb ratios. Lead isotope ratios were also measured on aerosol samples from urban areas and industrial sites of Sicily. The observed [sup 206]Pb/[sup 207]Pb range for urban and industrial aerosols matches the anthropogenic signature. Lichens instead, are closer to the compositional field of [sup 206]Pb rich geogenic sources. This natural input is more evident at Vulcano island than at Mt. Etna, where the anthropogenic activitiesmore » are considerably more effective. On the basis of lead isotope data, Pb/Br ratios and calculated lead enrichment factors, a natural lead pollution from volcanoes is suggested. Volcanic lead contribution ranges from 10 to 30% at Mt. Etna to 10--80% at Vulcano island.« less

18 CFR 154.208 - Service of tariff filings on customers and other parties.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Service of tariff filings on customers and other parties. 154.208 Section 154.208 Conservation of Power and Water Resources... SCHEDULES AND TARIFFS Procedures for Changing Tariffs § 154.208 Service of tariff filings on customers and...

18 CFR 154.208 - Service of tariff filings on customers and other parties.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Service of tariff filings on customers and other parties. 154.208 Section 154.208 Conservation of Power and Water Resources... SCHEDULES AND TARIFFS Procedures for Changing Tariffs § 154.208 Service of tariff filings on customers and...

18 CFR 154.208 - Service of tariff filings on customers and other parties.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Service of tariff filings on customers and other parties. 154.208 Section 154.208 Conservation of Power and Water Resources... SCHEDULES AND TARIFFS Procedures for Changing Tariffs § 154.208 Service of tariff filings on customers and...

18 CFR 154.208 - Service of tariff filings on customers and other parties.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Service of tariff filings on customers and other parties. 154.208 Section 154.208 Conservation of Power and Water Resources... SCHEDULES AND TARIFFS Procedures for Changing Tariffs § 154.208 Service of tariff filings on customers and...

10 CFR 835.208 - Limits for members of the public entering a controlled area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Limits for members of the public entering a controlled area. 835.208 Section 835.208 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Standards for Internal and External Exposure § 835.208 Limits for members of the public entering a controlled...

30 CFR 208.5 - Notice of royalty oil sale.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Notice of royalty oil sale. 208.5 Section 208.5... OF FEDERAL ROYALTY OIL General Provisions § 208.5 Notice of royalty oil sale. If the Secretary decides to take royalty oil in kind for sale to eligible refiners, MMS will issue a “Notice of...

22 CFR 208.205 - Why is it important to know if a particular transaction is a covered transaction?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Why is it important to know if a particular transaction is a covered transaction? 208.205 Section 208.205 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Covered Transactions § 208.205 Why is it...

19 CFR 201.208 - Tax refund offset.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 3 2010-04-01 2010-04-01 false Tax refund offset. 201.208 Section 201.208 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF GENERAL APPLICATION Debt Collection § 201.208 Tax refund offset. (a) Scope. The provisions of 26 U.S.C. 6402(d) and 31 U.S.C. 3720A...

19 CFR 201.208 - Tax refund offset.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 3 2011-04-01 2011-04-01 false Tax refund offset. 201.208 Section 201.208 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF GENERAL APPLICATION Debt Collection § 201.208 Tax refund offset. (a) Scope. The provisions of 26 U.S.C. 6402(d) and 31 U.S.C. 3720A...

19 CFR 201.208 - Tax refund offset.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 3 2013-04-01 2013-04-01 false Tax refund offset. 201.208 Section 201.208 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF GENERAL APPLICATION Debt Collection § 201.208 Tax refund offset. (a) Scope. The provisions of 26 U.S.C. 6402(d) and 31 U.S.C. 3720A...

19 CFR 201.208 - Tax refund offset.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 3 2012-04-01 2012-04-01 false Tax refund offset. 201.208 Section 201.208 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF GENERAL APPLICATION Debt Collection § 201.208 Tax refund offset. (a) Scope. The provisions of 26 U.S.C. 6402(d) and 31 U.S.C. 3720A...

19 CFR 201.208 - Tax refund offset.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 3 2014-04-01 2014-04-01 false Tax refund offset. 201.208 Section 201.208 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF GENERAL APPLICATION Debt Collection § 201.208 Tax refund offset. (a) Scope. The provisions of 26 U.S.C. 6402(d) and 31 U.S.C. 3720A...

23 CFR 636.208 - May I use my existing prequalification procedures with design-build contracts?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false May I use my existing prequalification procedures with design-build contracts? 636.208 Section 636.208 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS DESIGN-BUILD CONTRACTING Selection Procedures, Award Criteria § 636.208 May I use my existing...

22 CFR 208.305 - May I enter into a covered transaction with an excluded or disqualified person?

Code of Federal Regulations, 2011 CFR

2011-04-01

... excluded or disqualified person? 208.305 Section 208.305 Foreign Relations AGENCY FOR INTERNATIONAL... Regarding Transactions Doing Business with Other Persons § 208.305 May I enter into a covered transaction... transaction with an excluded person, unless the U.S. Agency for International Development grants an exception...

18 CFR 154.208 - Service of tariff filings on customers and other parties.

Code of Federal Regulations, 2010 CFR

2010-04-01

... filings on customers and other parties. 154.208 Section 154.208 Conservation of Power and Water Resources... SCHEDULES AND TARIFFS Procedures for Changing Tariffs § 154.208 Service of tariff filings on customers and other parties. (a) On or before the filing date, the company must serve, upon all customers as of the...

9 CFR 381.208 - Poultry products offered for entry and entered to be handled and transported as domestic; entry...

Code of Federal Regulations, 2010 CFR

2010-01-01

... INSPECTION AND CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS Imported Poultry Products § 381.208... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Poultry products offered for entry and....208 Section 381.208 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF...

22 CFR 208.305 - May I enter into a covered transaction with an excluded or disqualified person?

Code of Federal Regulations, 2010 CFR

2010-04-01

... excluded or disqualified person? 208.305 Section 208.305 Foreign Relations AGENCY FOR INTERNATIONAL... Regarding Transactions Doing Business with Other Persons § 208.305 May I enter into a covered transaction... transaction with an excluded person, unless the U.S. Agency for International Development grants an exception...

Methylene chloride exposure and carboxyhemoglobin levels in cabinetmakers.

PubMed

Banjoko, Sunny O; Sridhar Mynapelli, K C; Ogunkola, Isiah O; Masheyi, Olatunde O

2007-05-01

Methylene chloride (MeCl(2)) is a clear colorless volatile sweet smelling lipophilic solvent used as a constituent of wood vanishes and paints. Human exposure is mainly due to inhalation and its biotransformation by the hepatic mixed function oxidases (MFO) leads to formation of carbon monoxide (CO). Simultaneous exposure to MeCl(2) and increased ambient CO results in undesirably increased carboxyhemoglobin (COHb) formation, which predisposes to carboxyhemoglobinaemia with the central nervous system as the primary target organ of toxicity.In this study, ambient CO levels were determined using a CO personal monitor in different pasts of Ibadan Nigeria and work place microenvironment of 50 Cabinet makers (test group) and 50 volunteer (control) in non-furniture making occupations. Mann Whitney U and Kruskaal Wallis were the statistical methods of analysis used.Questionnaires were administered to both groups carboxyhaemoglobin levels were determined in venous blood drawn from individuals in the two groups by differential spectrophotometric method.Ambient CO levels in Ibadan were observed to be between 4 and 52 ppm with a mean of 20 ppm. Work environment CO levels were significantly higher in test subjects than controls at 5.2 ± 1.08 ppm and 2.08 ± 0.91 ppm respectively (P <0.001). COHb in cabinetmakers with mean working hours of 9.48 ± 2.9 per day was 3.95 ± 1.35 (%) while that of controls with mean working hours of 8.0 ± 0.8 per day was 2.08 ± 0.91 ppm (P <0.001). Smoking however did not significantly affect the COHb levels within the two groups (P >0.05).It is therefore imperative to substitute MeCl(2) for safer chemicals in wood vanish and paints and the use of protective gas masks and adequate ventilation should be mandatory whenever MeCl(2) is used.

Methylene chloride exposure and carboxyhemoglobin levels in cabinetmakers

PubMed Central

Banjoko, Sunny O.; Sridhar Mynapelli, K. C.; Ogunkola, Isiah O.; Masheyi, Olatunde O.

2007-01-01

Methylene chloride (MeCl2) is a clear colorless volatile sweet smelling lipophilic solvent used as a constituent of wood vanishes and paints. Human exposure is mainly due to inhalation and its biotransformation by the hepatic mixed function oxidases (MFO) leads to formation of carbon monoxide (CO). Simultaneous exposure to MeCl2 and increased ambient CO results in undesirably increased carboxyhemoglobin (COHb) formation, which predisposes to carboxyhemoglobinaemia with the central nervous system as the primary target organ of toxicity. In this study, ambient CO levels were determined using a CO personal monitor in different pasts of Ibadan Nigeria and work place microenvironment of 50 Cabinet makers (test group) and 50 volunteer (control) in non-furniture making occupations. Mann Whitney U and Kruskaal Wallis were the statistical methods of analysis used. Questionnaires were administered to both groups carboxyhaemoglobin levels were determined in venous blood drawn from individuals in the two groups by differential spectrophotometric method. Ambient CO levels in Ibadan were observed to be between 4 and 52 ppm with a mean of 20 ppm. Work environment CO levels were significantly higher in test subjects than controls at 5.2 ± 1.08 ppm and 2.08 ± 0.91 ppm respectively (P <0.001). COHb in cabinetmakers with mean working hours of 9.48 ± 2.9 per day was 3.95 ± 1.35 (%) while that of controls with mean working hours of 8.0 ± 0.8 per day was 2.08 ± 0.91 ppm (P <0.001). Smoking however did not significantly affect the COHb levels within the two groups (P >0.05). It is therefore imperative to substitute MeCl2 for safer chemicals in wood vanish and paints and the use of protective gas masks and adequate ventilation should be mandatory whenever MeCl2 is used. PMID:21938216

Site overview. Part 1 of 3part panorama with nos. CA27022 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Site overview. Part 1 of 3-part panorama with nos. CA-2702-2 and CA-2707-3. Southern LTA ship hangar (building 28; hangar no. 2 in distant center of photograph. Seen from roadway leading to northern LTA ship hangar (building 29; hangar no. 1) landing pad. Looking 208 SSW. - Marine Corps Air Station Tustin, East of Red Hill Avenue between Edinger Avenue & Barranca Parkway, Tustin, Orange County, CA

Site overview. Part 1 of 3part panorama with nos. CA27022 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Site overview. Part 1 of 3-part panorama with nos. CA-2702-2 and CA-2707-3. Southern LTA ship hangar (building 28; hangar no. 2 in distant center of photograph. Seen from roadway leading to northern LTA ship hangar (building 29; hangar no. 1) landing pad. Looking 208 SSW. - Marine Corps Air Station Tustin, Northern Lighter Than Air Ship Hangar, Meffett Avenue & Maxfield Street, Tustin, Orange County, CA

22 CFR 208.320 - Must I verify that principals of my covered transactions are eligible to participate?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Must I verify that principals of my covered transactions are eligible to participate? 208.320 Section 208.320 Foreign Relations AGENCY FOR INTERNATIONAL... Regarding Transactions Doing Business with Other Persons § 208.320 Must I verify that principals of my...

22 CFR 208.325 - What happens if I do business with an excluded person in a covered transaction?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false What happens if I do business with an excluded person in a covered transaction? 208.325 Section 208.325 Foreign Relations AGENCY FOR INTERNATIONAL... Regarding Transactions Doing Business with Other Persons § 208.325 What happens if I do business with an...

22 CFR 208.310 - What must I do if a Federal agency excludes a person with whom I am already doing business in a...

Code of Federal Regulations, 2011 CFR

2011-04-01

... person with whom I am already doing business in a covered transaction? 208.310 Section 208.310 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Responsibilities of Participants Regarding Transactions Doing Business with Other Persons § 208.310 What must I do...

22 CFR 208.325 - What happens if I do business with an excluded person in a covered transaction?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false What happens if I do business with an excluded person in a covered transaction? 208.325 Section 208.325 Foreign Relations AGENCY FOR INTERNATIONAL... Regarding Transactions Doing Business with Other Persons § 208.325 What happens if I do business with an...

22 CFR 208.320 - Must I verify that principals of my covered transactions are eligible to participate?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Must I verify that principals of my covered transactions are eligible to participate? 208.320 Section 208.320 Foreign Relations AGENCY FOR INTERNATIONAL... Regarding Transactions Doing Business with Other Persons § 208.320 Must I verify that principals of my...

22 CFR 208.310 - What must I do if a Federal agency excludes a person with whom I am already doing business in a...

Code of Federal Regulations, 2010 CFR

2010-04-01

... person with whom I am already doing business in a covered transaction? 208.310 Section 208.310 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Responsibilities of Participants Regarding Transactions Doing Business with Other Persons § 208.310 What must I do...

12 CFR 208.71 - What are the requirements to invest in or control a financial subsidiary?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 2 2010-01-01 2010-01-01 false What are the requirements to invest in or control a financial subsidiary? 208.71 Section 208.71 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF... SYSTEM (REGULATION H) Financial Subsidiaries of State Member Banks § 208.71 What are the requirements to...

Assessment of Proper Bonding Methods and Mechanical Characterization FPGA CQFPs

NASA Technical Reports Server (NTRS)

Davis, Milton C.

2008-01-01

This presentation discusses fractured leads on field-programmable gate array (FPGA) during flight vibration. Actions taken to determine root cause and resolution of the failure include finite element analysis (FEA) and vibration testing and scanning electron microscopy (with X-ray microanalysis) and energy dispersive spectrometry (SEM/EDS) failure assessment. Bonding methods for surface mount parts is assessed, including critical analysis and assessment of random fatigue damage. Regarding ceramic quad flat pack (CQFP) lead fracture, after disassembling the attitude control electronics (ACE) configuration, photographs showed six leads cracked on FPGA RTSX72SU-1 CQ208B package located on the RWIC card. An identical package (FPGA RTSX32SU-1 CQ208B) mounted on the RWIC did not results in cracked pins due to vibration. FPGA lead failure theories include workmanship issues in the lead-forming, material defect in the leads of the FPGA packages, and the insecure mounting of the board in the card guides, among other theories. Studies were conducted using simple calculations to determine the response and fatigue life of the package. Shorter packages exhibited more response when loaded by out-of-plane displacement of PCB while taller packages exhibit more response when loaded by in-plane acceleration of PCB. Additionally, under-fill did not contribute to reducing stress in leads due to out-of-plane PCB loading or from component twisting, as much as corner bonding. The combination of corner bond and under-fill is best to address mechanical and thermal S/C environment. Test results of bonded parts showed reduced (dampened) amplitude and slightly shifted peaks at the un-bonded natural frequency and an additional response at the bonded frequency. Stress due to PCBB out-of-plane loading was decreased on in the corners when only a corner bond was used. Future work may address CQFP fatigue assessment, including the investigation of discrepancy in predicted fatigue damage, as well as comparing fatigue life and fatigue damage cycle ration computed using FEA and Miner's rule to results from a fatigue assessment software program.

Dopamine receptor antagonists as new mode-of-action insecticide leads for control of Aedes and Culex mosquito vectors.

PubMed

Nuss, Andrew B; Ejendal, Karin F K; Doyle, Trevor B; Meyer, Jason M; Lang, Emma G; Watts, Val J; Hill, Catherine A

2015-03-01

New mode-of-action insecticides are sought to provide continued control of pesticide resistant arthropod vectors of neglected tropical diseases (NTDs). We previously identified antagonists of the AaDOP2 D1-like dopamine receptor (DAR) from the yellow fever mosquito, Aedes aegypti, with toxicity to Ae. aegypti larvae as leads for novel insecticides. To extend DAR-based insecticide discovery, we evaluated the molecular and pharmacological characteristics of an orthologous DAR target, CqDOP2, from Culex quinquefasciatus, the vector of lymphatic filariasis and West Nile virus. CqDOP2 has 94.7% amino acid identity to AaDOP2 and 28.3% identity to the human D1-like DAR, hD1. CqDOP2 and AaDOP2 exhibited similar pharmacological responses to biogenic amines and DAR antagonists in cell-based assays. The antagonists amitriptyline, amperozide, asenapine, chlorpromazine and doxepin were between 35 to 227-fold more selective at inhibiting the response of CqDOP2 and AaDOP2 in comparison to hD1. Antagonists were toxic to both C. quinquefasciatus and Ae. aegypti larvae, with LC50 values ranging from 41 to 208 μM 72 h post-exposure. Orthologous DOP2 receptors identified from the African malaria mosquito, Anopheles gambiae, the sand fly, Phlebotomus papatasi and the tsetse fly, Glossina morsitans, had high sequence similarity to CqDOP2 and AaDOP2. DAR antagonists represent a putative new insecticide class with activity against C. quinquefasciatus and Ae. aegypti, the two most important mosquito vectors of NTDs. There has been limited change in the sequence and pharmacological properties of the DOP2 DARs of these species since divergence of the tribes Culicini and Aedini. We identified antagonists selective for mosquito versus human DARs and observed a correlation between DAR pharmacology and the in vivo larval toxicity of antagonists. These data demonstrate that sequence similarity can be predictive of target potential. On this basis, we propose expanded insecticide discovery around orthologous DOP2 targets from additional dipteran vectors.

Pressure-induced zigzag phosphorus chain and superconductivity in boron monophosphide.

PubMed

Zhang, Xinyu; Qin, Jiaqian; Liu, Hanyu; Zhang, Shiliang; Ma, Mingzhen; Luo, Wei; Liu, Riping; Ahuja, Rajeev

2015-03-04

We report on the prediction of the zinc-blende structure BP into a novel C2/m phase from 113 to 208 GPa which possesses zigzag phosphorus chain structure, followed by another P42/mnm structure above 208 GPa above using the particle-swarm search method. Strong electron-phonon coupling λ in compressed BP is found, in particular for C2/m phase with the zigzag phosphorus chain, which has the highest λ (0.56-0.61) value among them, leading to its high superconducting critical temperature Tc (9.4 K-11.5 K), which is comparable with the 4.5 K to 13 K value of black phosphorus phase I (orthorhombic, Cmca). This is the first system in the boron phosphides which shows superconductivity from the present theoretical calculations. Our results show that pressure-induced zigzag phosphorus chain in BP exhibit higher superconducting temperature TC, opening a new route to search and design new superconductor materials with zigzag phosphorus chains.

Unexpected opioid activity profiles of analogues of the novel peptide kappa opioid receptor ligand CJ-15,208.

PubMed

Aldrich, Jane V; Kulkarni, Santosh S; Senadheera, Sanjeewa N; Ross, Nicolette C; Reilley, Kate J; Eans, Shainnel O; Ganno, Michelle L; Murray, Thomas F; McLaughlin, Jay P

2011-09-05

An alanine scan was performed on the novel κ opioid receptor (KOR) peptide ligand CJ-15,208 to determine which residues contribute to the potent in vivo agonist activity observed for the parent peptide. These cyclic tetrapeptides were synthesized by a combination of solid-phase peptide synthesis of the linear precursors, followed by cyclization in solution. Like the parent peptide, each of the analogues exhibited agonist activity and KOR antagonist activity in an antinociceptive assay in vivo. Unlike the parent peptide, the agonist activity of the potent analogues was mediated predominantly, if not exclusively, by μ opioid receptors (MOR). Thus analogues 2 and 4, in which one of the phenylalanine residues was replaced by alanine, exhibited both potent MOR agonist activity and KOR antagonist activity in vivo. These peptides represent novel lead compounds for the development of peptide-based opioid analgesics. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

22 CFR 208.360 - What happens if I fail to disclose the information required under § 208.355?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false What happens if I fail to disclose the... Regarding Transactions Disclosing Information-Lower Tier Participants § 208.360 What happens if I fail to disclose the information required under § 208.355? If we later determine that you failed to tell the person...

22 CFR 208.360 - What happens if I fail to disclose the information required under § 208.355?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false What happens if I fail to disclose the... Regarding Transactions Disclosing Information-Lower Tier Participants § 208.360 What happens if I fail to disclose the information required under § 208.355? If we later determine that you failed to tell the person...

22 CFR 208.830 - Under what conditions do I get an additional opportunity to challenge the facts on which the...

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Under what conditions do I get an additional opportunity to challenge the facts on which the proposed debarment is based? 208.830 Section 208.830 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Debarment § 208.830 Under what...

12 CFR Appendix B to Part 208 - Capital Adequacy Guidelines for State Member Banks: Tier 1 Leverage Measure

Code of Federal Regulations, 2014 CFR

2014-01-01

... Banks: Tier 1 Leverage Measure B Appendix B to Part 208 Banks and Banking FEDERAL RESERVE SYSTEM BOARD... RESERVE SYSTEM (REGULATION H) Pt. 208, App. B Appendix B to Part 208—Capital Adequacy Guidelines for State... state member banks are outlined in Appendix A to this part. b. The guidelines apply to all state member...

49 CFR 40.208 - What problem requires corrective action but does not result in the cancellation of a test?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 1 2013-10-01 2013-10-01 false What problem requires corrective action but does not result in the cancellation of a test? 40.208 Section 40.208 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Problems in Drug Tests § 40.208 What problem requires...

25 CFR 900.208 - How are non-medical related tort claims and lawsuits filed for DOI?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false How are non-medical related tort claims and lawsuits filed for DOI? 900.208 Section 900.208 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR, AND... Related Claims § 900.208 How are non-medical related tort claims and lawsuits filed for DOI? Non-medical...

25 CFR 900.208 - How are non-medical related tort claims and lawsuits filed for DOI?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false How are non-medical related tort claims and lawsuits filed for DOI? 900.208 Section 900.208 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR, AND... Related Claims § 900.208 How are non-medical related tort claims and lawsuits filed for DOI? Non-medical...

Probing Novel Properties of Nucleons and Nuclei via Parity Violating Electron Scattering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mercado, Luis

2012-05-01

This thesis reports on two experiments conducted by the HAPPEx (Hall A Proton Parity Experiment) collaboration at the Thomas Jefferson National Accelerator Facility. For both, the weak neutral current interaction (WNC, mediated by the Z 0 boson) is used to probe novel properties of hadronic targets. The WNC interaction amplitude is extracted by measuring the parity-violating asymmetry in the elastic scattering of longitudinally polarized electrons o unpolarized target hadrons. HAPPEx-III, conducted in the Fall of 2009, used a liquid hydrogen target at a momentum transfer of Q 2 = 0.62 GeV 2. The measured asymmetry was used to set newmore » constraints on the contribution of strange quark form factors (G s E,M ) to the nucleon electromagnetic form factors. A value of A PV = -23.803±} 0.778 (stat)± 0.359 (syst) ppm resulted in G s E + 0.517G s M = 0.003± 0.010 (stat)± 0.004 (syst)± 0.009 (FF). PREx, conducted in the Spring of 2010, used a polarized electron beam on a 208Pb target at a momentum transfer of Q 2 = 0.009 GeV 2. This parity-violating asymmetry can be used to obtain a clean measurement of the root-mean-square radius of the neutrons in the 208Pb nucleus. The Z 0 boson couples mainly to neutrons; the neutron weak charge is much larger than that of the proton. The value of this asymmetry is at the sub-ppm level and has a projected experimental fractional precision of 3%. We will describe the accelerator setup used to set controls on helicity-correlated beam asymmetries and the analysis methods for finding the raw asymmetry for HAPPEx-III. We will also discuss in some detail the preparations to meet the experimental challenges associated with measuring such a small asymmetry with the degree of precision required for PREx.« less

Epidermal Growth Factor Receptor Overexpression as a Target for Auger Electron Radiotherapy of Breast Cancer

DTIC Science & Technology

2002-08-01

treatment of mice with 92.5 MBq (2.5 mCi) of ..In-DTPA-hEGF in five divided weekly doses. * Cumulative Radioactivity in Source Compartment (,s, Bq x...equiv- nalization of the radiopharmaceutical resulted in selective alent to a human dose of 14,208 MBq /m 2) can be safely and enhanced cytotoxicity in... be construed as an official Department of the Army position, policy or decision unless so designated by other documentation. " ROIForm Approved

48 CFR 208.002 - Priorities for use of Government supply sources.

Code of Federal Regulations, 2010 CFR

2010-10-01

... REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE ACQUISITION PLANNING REQUIRED SOURCES OF SUPPLIES AND SERVICES 208... Acquisition, and Subpart 208.74, Enterprise Software Agreements. [71 FR 39004, July 11, 2006] ...

Elevated blood lead levels from exposure via a radiator workshop.

PubMed

Treble, R G; Thompson, T S; Morton, D N

1998-04-01

Elevated lead levels were discovered in blood samples collected from family members where both the father and the mother worked in a radiator repair workshop. The father and mother were found to have blood lead levels of 2.0 and 0.5 mumol/L (41.7 and 10.4 micrograms/dL), respectively. The father's blood lead level was just below the Canadian occupational health and safety intervention level (2.5 mumol/L or 52.1 micrograms/dL). The two children had blood lead levels of 1.0 and 0.8 mumol/L (20.8 and 16.7 micrograms/dL), both of which are in excess of the recommended guideline for intervention in the case of children (0.5 mumol/L or 10.4 micrograms/dL). The exposure of the two children was possibly due to a combination of pathways including exposure at the workshop itself during visits and also the transportation of lead-containing dust to the home environment.

22 CFR 208.415 - What must I do if a Federal agency excludes the participant or a principal after I enter into a...

Code of Federal Regulations, 2010 CFR

2010-04-01

... that the action is proper. (b) You may not renew or extend covered transactions (other than no-cost... participant or a principal after I enter into a covered transaction? 208.415 Section 208.415 Foreign Relations...) Responsibilities of USAID Officials Regarding Transactions § 208.415 What must I do if a Federal agency excludes...

48 CFR 208.7001 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Program. Integrated materiel management means assignment of acquisition management responsibility to one... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Definitions. 208.7001 Section 208.7001 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT...

48 CFR 208.7001 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Program. Integrated materiel management means assignment of acquisition management responsibility to one... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Definitions. 208.7001 Section 208.7001 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT...

48 CFR 208.7001 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Program. Integrated materiel management means assignment of acquisition management responsibility to one... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Definitions. 208.7001 Section 208.7001 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT...

48 CFR 208.7001 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Program. Integrated materiel management means assignment of acquisition management responsibility to one... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Definitions. 208.7001 Section 208.7001 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT...

48 CFR 208.7001 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Program. Integrated materiel management means assignment of acquisition management responsibility to one... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Definitions. 208.7001 Section 208.7001 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT...

48 CFR 208.7403 - Acquisition procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SYSTEM, DEPARTMENT OF DEFENSE ACQUISITION PLANNING REQUIRED SOURCES OF SUPPLIES AND SERVICES Enterprise Software Agreements 208.7403 Acquisition procedures. Follow the procedures at PGI 208.7403 when acquiring commercial software and related services. [71 FR 39005, July 11, 2006] ...

76 FR 40709 - 36(b)(1) Arms Sales Notification

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-11

... aircraft systems that include TC-208s, Cessna 172s, AC-208s, T-6As, and King Air 350s. Included are ground... Force (QAF Amd 4, QAH, Amd 4) (v) Prior Related Cases, if any: FMS case QAS-$33M-21Sep10 FMS case SAD... systems that include TC- 208s, Cessna 172s, AC-208s, T-6As, and King Air 350s. Included are ground...

22 CFR 208.365 - What must I do if I learn of information required under § 208.355 after entering into a covered...

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false What must I do if I learn of information...-Lower Tier Participants § 208.365 What must I do if I learn of information required under § 208.355... written notice to that person if you learn either that— (a) You failed to disclose information earlier, as...

22 CFR 208.365 - What must I do if I learn of information required under § 208.355 after entering into a covered...

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false What must I do if I learn of information...-Lower Tier Participants § 208.365 What must I do if I learn of information required under § 208.355... written notice to that person if you learn either that— (a) You failed to disclose information earlier, as...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saenboonruang, Kiadtisak

In contrast to the nuclear charge densities, which have been accurately measured with electron scattering, the knowledge of neutron densities still lack precision. Previous model-dependent hadron experiments suggest the difference between the neutron radius, R n, of a heavy nucleus and the proton radius, R p, to be in the order of several percent. To accurately obtain the difference, R n-R p, which is essentially a neutron skin, the Jefferson Lab Lead ( 208Pb) Radius Experiment (PREX) measured the parity-violating electroweak asymmetry in the elastic scattering of polarized electrons from 208Pb at an energy of 1.06 GeV and a scatteringmore » angle of 5° . Since Z 0 boson couples mainly to neutrons, this asymmetry provides a clean measurement of R n with respect to R p. PREX was conducted at the Jefferson lab experimental Hall A, from March to June 2010. The experiment collected a final data sample of 2x 10 7 helicity-window quadruplets. The measured parity-violating electroweak asymmetry A PV = 0.656 ± 0.060 (stat) ± 0.014 (syst) ppm corresponds to a difference between the radii of the neutron and proton distributions, R n-R p = 0.33 +0.16 -0.18 fm and provides the first electroweak observation of the neutron skin as expected in a heavy, neutron-rich nucleus. The value of the neutron radius of 208Pb has important implications for models of nuclear structure and their application in atomic physics and astrophysics such as atomic parity non-conservation (PNC) and neutron stars.« less

Microscopic few-body and Gaussian-shaped density distributions for the analysis of the 6He exotic nucleus with different target nuclei

NASA Astrophysics Data System (ADS)

Aygun, M.; Kucuk, Y.; Boztosun, I.; Ibraheem, Awad A.

2010-12-01

The elastic scattering angular distributions of 6He projectile on different medium and heavy mass target nuclei including 12C, 27Al, 58Ni, 64Zn, 65Cu, 197Au, 208Pb and 209Bi have been examined by using the few-body and Gaussian-shaped density distributions at various energies. The microscopic real parts of the complex nuclear optical potential have been obtained by using the double-folding model for each of the density distributions and the phenomenological imaginary potentials have been taken as the Woods-Saxon type. Comparative results of the few-body and Gaussian-shaped density distributions together with the experimental data are presented within the framework of the optical model.

22 CFR 208.900 - Adequate evidence.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Adequate evidence. 208.900 Section 208.900 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE DEBARMENT AND SUSPENSION... support the reasonable belief that a particular act or omission has occurred. ...

22 CFR 208.900 - Adequate evidence.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Adequate evidence. 208.900 Section 208.900 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE DEBARMENT AND SUSPENSION... support the reasonable belief that a particular act or omission has occurred. ...

40 CFR 61.208 - Certification requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Certification requirements. 61.208 Section 61.208 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standards for Radon...

40 CFR 61.208 - Certification requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 8 2011-07-01 2011-07-01 false Certification requirements. 61.208 Section 61.208 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standards for Radon...

Deregulated Cardiac Specific MicroRNAs in Postnatal Heart Growth.

PubMed

Yu, Pujiao; Wang, Hongbao; Xie, Yuan; Zhou, Jinzhe; Yao, Jianhua; Che, Lin

2016-01-01

The heart is recognized as an organ that is terminally differentiated by adulthood. However, during the process of human development, the heart is the first organ with function in the embryo and grows rapidly during the postnatal period. MicroRNAs (miRNAs, miRs), as regulators of gene expression, play important roles during the development of multiple systems. However, the role of miRNAs in postnatal heart growth is still unclear. In this study, by using qRT-PCR, we compared the expression of seven cardiac- or muscle-specific miRNAs that may be related to heart development in heart tissue from mice at postnatal days 0, 3, 8, and 14. Four miRNAs-miR-1a-3p, miR-133b-3p, miR-208b-3p, and miR-206-3p-were significantly decreased while miR-208a-3p was upregulated during the postnatal heart growth period. Based on these results, GeneSpring GX was used to predict potential downstream targets by performing a 3-way comparison of predictions from the miRWalk, PITA, and microRNAorg databases. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis were used to identify potential functional annotations and signaling pathways related to postnatal heart growth. This study describes expression changes of cardiac- and muscle-specific miRNAs during postnatal heart growth and may provide new therapeutic targets for cardiovascular diseases.

29 CFR 1603.208 - Motions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 4 2010-07-01 2010-07-01 false Motions. 1603.208 Section 1603.208 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF THE...

29 CFR 1603.208 - Motions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 4 2012-07-01 2012-07-01 false Motions. 1603.208 Section 1603.208 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF THE...

29 CFR 1603.208 - Motions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 4 2013-07-01 2013-07-01 false Motions. 1603.208 Section 1603.208 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF THE...

29 CFR 1603.208 - Motions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 4 2011-07-01 2011-07-01 false Motions. 1603.208 Section 1603.208 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF THE...

29 CFR 1603.208 - Motions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 4 2014-07-01 2014-07-01 false Motions. 1603.208 Section 1603.208 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF THE...

48 CFR 208.7002 - Assignment authority.

Code of Federal Regulations, 2012 CFR

2012-10-01

... activities concerned. (b) Under the Integrated Materiel Management Program, assignments are made by the... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Assignment authority. 208.7002 Section 208.7002 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM...

48 CFR 208.7002 - Assignment authority.

Code of Federal Regulations, 2013 CFR

2013-10-01

... activities concerned. (b) Under the Integrated Materiel Management Program, assignments are made by the... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Assignment authority. 208.7002 Section 208.7002 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM...

48 CFR 208.7002 - Assignment authority.

Code of Federal Regulations, 2011 CFR

2011-10-01

... activities concerned. (b) Under the Integrated Materiel Management Program, assignments are made by the... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Assignment authority. 208.7002 Section 208.7002 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM...

48 CFR 208.7002 - Assignment authority.

Code of Federal Regulations, 2014 CFR

2014-10-01

... activities concerned. (b) Under the Integrated Materiel Management Program, assignments are made by the... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Assignment authority. 208.7002 Section 208.7002 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM...

31 CFR 208.3 - Payment by electronic funds transfer.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false Payment by electronic funds transfer... DISBURSEMENTS § 208.3 Payment by electronic funds transfer. Subject to § 208.4, and notwithstanding any other... electronic funds transfer. ...

31 CFR 208.3 - Payment by electronic funds transfer.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 2 2012-07-01 2012-07-01 false Payment by electronic funds transfer... DISBURSEMENTS § 208.3 Payment by electronic funds transfer. Subject to § 208.4, and notwithstanding any other... electronic funds transfer. ...

The macrocyclic tetrapeptide [D-Trp]CJ-15,208 produces short-acting κ opioid receptor antagonism in the CNS after oral administration

PubMed Central

Eans, Shainnel O; Ganno, Michelle L; Reilley, Kate J; Patkar, Kshitij A; Senadheera, Sanjeewa N; Aldrich, Jane V; McLaughlin, Jay P

2013-01-01

Background and Purpose Cyclic peptides are resistant to proteolytic cleavage, therefore potentially exhibiting activity after systemic administration. We hypothesized that the macrocyclic κ opioid receptor (KOR)-selective antagonist [D-Trp]CJ-15,208 would demonstrate antagonist activity after systemic, that is, s.c. and oral (per os, p. o.), administration. Experimental Approach C57BL/6J mice were pretreated with [D-Trp]CJ-15,208 s.c. or p.o. before administration of the KOR-selective agonist U50,488 and the determination of antinociception in the warm-water tail-withdrawal assay. The locomotor activity of mice treated with [D-Trp]CJ-15,208 was determined by rotorod testing. Additional mice demonstrating cocaine conditioned place preference and subsequent extinction were pretreated daily with vehicle or [D-Trp]CJ-15,208 and then exposed to repeated forced swim stress or a single additional session of cocaine place conditioning before redetermining place preference. Key Results Pretreatment with [D-Trp]CJ-15,208 administered s.c. or p.o. dose-dependently antagonized the antinociception induced by i.p. administration of U50,488 in mice tested in the warm-water tail-withdrawal assay for less than 12 and 6 h respectively. [D-Trp]CJ-15,208 also produced limited (<25%), short-duration antinociception mediated through KOR agonism. Orally administered [D-Trp]CJ-15,208 dose-dependently antagonized centrally administered U50,488-induced antinociception, and prevented stress-, but not cocaine-induced, reinstatement of extinguished cocaine-seeking behaviour, consistent with its KOR antagonist activity, without affecting locomotor activity. Conclusions and Implications The macrocyclic tetrapeptide [D-Trp]CJ-15,208 is a short-duration KOR antagonist with weak KOR agonist activity that is active after oral administration and demonstrates blood–brain barrier permeability. These data validate the use of systemically active peptides such as [D-Trp]CJ-15,208 as potentially useful therapeutics. PMID:23425081

The macrocyclic tetrapeptide [D-Trp]CJ-15,208 produces short-acting κ opioid receptor antagonism in the CNS after oral administration.

PubMed

Eans, Shainnel O; Ganno, Michelle L; Reilley, Kate J; Patkar, Kshitij A; Senadheera, Sanjeewa N; Aldrich, Jane V; McLaughlin, Jay P

2013-05-01

Cyclic peptides are resistant to proteolytic cleavage, therefore potentially exhibiting activity after systemic administration. We hypothesized that the macrocyclic κ opioid receptor (KOR)-selective antagonist [D-Trp]CJ-15,208 would demonstrate antagonist activity after systemic, that is, s.c. and oral (per os, p. o.), administration. C57BL/6J mice were pretreated with [D-Trp]CJ-15,208 s.c. or p.o. before administration of the KOR-selective agonist U50,488 and the determination of antinociception in the warm-water tail-withdrawal assay. The locomotor activity of mice treated with [D-Trp]CJ-15,208 was determined by rotorod testing. Additional mice demonstrating cocaine conditioned place preference and subsequent extinction were pretreated daily with vehicle or [D-Trp]CJ-15,208 and then exposed to repeated forced swim stress or a single additional session of cocaine place conditioning before redetermining place preference. Pretreatment with [D-Trp]CJ-15,208 administered s.c. or p.o. dose-dependently antagonized the antinociception induced by i.p. administration of U50,488 in mice tested in the warm-water tail-withdrawal assay for less than 12 and 6 h respectively. [D-Trp]CJ-15,208 also produced limited (<25%), short-duration antinociception mediated through KOR agonism. Orally administered [D-Trp]CJ-15,208 dose-dependently antagonized centrally administered U50,488-induced antinociception, and prevented stress-, but not cocaine-induced, reinstatement of extinguished cocaine-seeking behaviour, consistent with its KOR antagonist activity, without affecting locomotor activity. The macrocyclic tetrapeptide [D-Trp]CJ-15,208 is a short-duration KOR antagonist with weak KOR agonist activity that is active after oral administration and demonstrates blood-brain barrier permeability. These data validate the use of systemically active peptides such as [D-Trp]CJ-15,208 as potentially useful therapeutics. © 2013 The Authors. British Journal of Pharmacology © 2013 The British Pharmacological Society.

Role of Loop-Clamping Side Chains in Catalysis by Triosephosphate Isomerase.

PubMed

Zhai, Xiang; Amyes, Tina L; Richard, John P

2015-12-09

The side chains of Y208 and S211 from loop 7 of triosephosphate isomerase (TIM) form hydrogen bonds to backbone amides and carbonyls from loop 6 to stabilize the caged enzyme-substrate complex. The effect of seven mutations [Y208T, Y208S, Y208A, Y208F, S211G, S211A, Y208T/S211G] on the kinetic parameters for TIM catalyzed reactions of the whole substrates dihydroxyacetone phosphate and d-glyceraldehyde 3-phosphate [(k(cat)/K(m))(GAP) and (k(cat)/K(m))DHAP] and of the substrate pieces glycolaldehyde and phosphite dianion (k(cat)/K(HPi)K(GA)) are reported. The linear logarithmic correlation between these kinetic parameters, with slope of 1.04 ± 0.03, shows that most mutations of TIM result in an identical change in the activation barriers for the catalyzed reactions of whole substrate and substrate pieces, so that the transition states for these reactions are stabilized by similar interactions with the protein catalyst. The second linear logarithmic correlation [slope = 0.53 ± 0.16] between k(cat) for isomerization of GAP and K(d)(⧧) for phosphite dianion binding to the transition state for wildtype and many mutant TIM-catalyzed reactions of substrate pieces shows that ca. 50% of the wildtype TIM dianion binding energy, eliminated by these mutations, is expressed at the wildtype Michaelis complex, and ca. 50% is only expressed at the wildtype transition state. Negative deviations from this correlation are observed when the mutation results in a decrease in enzyme reactivity at the catalytic site. The main effect of Y208T, Y208S, and Y208A mutations is to cause a reduction in the total intrinsic dianion binding energy, but the effect of Y208F extends to the catalytic site.

Laser photochemical lead isotopes separation for harmless nuclear power engineering

NASA Astrophysics Data System (ADS)

Bokhan, P. A.; Fateev, N. V.; Kim, V. A.; Zakrevsky, D. E.

2016-09-01

The collisional quenching of the metastable 3 P 1,2 and 1 D 2 lead atoms is studied experimentally in the gas flow of the lead atoms, reagent-molecules and a carrier gas Ar. The experimental parameters were similar to the conditions that are required in the operation of the experimental setup for photochemical isotope separation. Excited atoms are generated under electron impact conditions created by a gas glow discharge through the mixture of gases and monitored photoelectrically by attenuation of atomic resonance radiation from hollow cathode 208Pb lamp. The decay of the excited atoms has been studied in the presence various molecules and total cross section data are reported. The flow tube measurements has allowed to separate the physical and chemical quenching channels and measure the rates of the chemical reaction excited lead with N2O, CH2Cl2, SF6 and CuBr molecules. These results are discussed in the prospects of the obtaining isotopically modified lead as a promising coolant in the reactors on the fast-neutron.

7 CFR 330.208 - Courtesy permits.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 5 2011-01-01 2011-01-01 false Courtesy permits. 330.208 Section 330.208 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FEDERAL PLANT PEST REGULATIONS; GENERAL; PLANT PESTS; SOIL, STONE, AND QUARRY...

7 CFR 330.208 - Courtesy permits.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 5 2014-01-01 2014-01-01 false Courtesy permits. 330.208 Section 330.208 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FEDERAL PLANT PEST REGULATIONS; GENERAL; PLANT PESTS; SOIL, STONE, AND QUARRY...

7 CFR 330.208 - Courtesy permits.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 5 2013-01-01 2013-01-01 false Courtesy permits. 330.208 Section 330.208 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FEDERAL PLANT PEST REGULATIONS; GENERAL; PLANT PESTS; SOIL, STONE, AND QUARRY...

7 CFR 330.208 - Courtesy permits.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 5 2012-01-01 2012-01-01 false Courtesy permits. 330.208 Section 330.208 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FEDERAL PLANT PEST REGULATIONS; GENERAL; PLANT PESTS; SOIL, STONE, AND QUARRY...

7 CFR 330.208 - Courtesy permits.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Courtesy permits. 330.208 Section 330.208 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FEDERAL PLANT PEST REGULATIONS; GENERAL; PLANT PESTS; SOIL, STONE, AND QUARRY...

7 CFR 205.208-205.235 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false [Reserved] 205.208-205.235 Section 205.208-205.235 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) ORGANIC FOODS PRODUCTION ACT...

40 CFR 6.208 - Records of decision.

Code of Federal Regulations, 2010 CFR

2010-07-01

....208 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROCEDURES FOR IMPLEMENTING THE NATIONAL ENVIRONMENTAL POLICY ACT AND ASSESSING THE ENVIRONMENTAL EFFECTS ABROAD OF EPA ACTIONS EPA's NEPA Environmental Review Procedures § 6.208 Records of decision. (a) The Responsible Official may not make any...

31 CFR 208.8 - Recipient responsibilities.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Recipient responsibilities. 208.8 Section 208.8 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL AGENCY...

31 CFR 208.7 - Agency responsibilities.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Agency responsibilities. 208.7 Section 208.7 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL AGENCY...

44 CFR 206.208 - Direct Federal assistance.

Code of Federal Regulations, 2010 CFR

2010-10-01

...) Project management. (1) The performing Federal agency shall ensure that the work is completed in... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Direct Federal assistance. 206.208 Section 206.208 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY...

24 CFR 880.208 - Financing.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Financing. 880.208 Section 880.208 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF THE ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN...

40 CFR 761.208 - Obtaining manifests.

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.208 Obtaining manifests. (a)(1) A generator may use... 761.208 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL...) Commercial printer; (iii) PCB waste generator, transporter or, designated facility; or (iv) PCB waste broker...

40 CFR 761.208 - Obtaining manifests.

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.208 Obtaining manifests. (a)(1) A generator may use... 761.208 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL...) Commercial printer; (iii) PCB waste generator, transporter or, designated facility; or (iv) PCB waste broker...

48 CFR 49.208 - Equitable adjustment after partial termination.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Equitable adjustment after partial termination. 49.208 Section 49.208 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TERMINATION OF CONTRACTS Additional Principles for Fixed-Price Contracts...

40 CFR 240.208-3 - Recommended procedures: Operations.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Operations. 240.208-3 Section 240.208-3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended...

31 CFR 800.208 - Critical infrastructure.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Critical infrastructure. 800.208 Section 800.208 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF INVESTMENT SECURITY, DEPARTMENT OF THE TREASURY REGULATIONS PERTAINING TO MERGERS, ACQUISITIONS...

8 CFR 208.12 - Reliance on information compiled by other sources.

Code of Federal Regulations, 2010 CFR

2010-01-01

... whether the alien has a credible fear of persecution or torture pursuant to § 208.30 of this part, or a reasonable fear of persecution or torture pursuant to § 208.31, the asylum officer may rely on material...

1. STREETSCAPE VIEW OF 208 VINE STREET (FIRST HOUSE ON ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. STREETSCAPE VIEW OF 208 VINE STREET (FIRST HOUSE ON RIGHT) LOOKING WEST. THIS STRUCTURE WAS ONE OF APPROXIMATELY SEVENTEEN DUPLEXES BUILT AS THE ORIGINAL WORKER HOUSING FOR THE LaGRANGE COTTON MILLS, LATER KNOWN AS CALUMET MILL. LaGRANGE MILLS (1888-89) WAS THE FIRST COTTON MILL IN LaGRANGE. NOTE THE GABLE-ON-HIP ROOF FORM AND IDENTICAL STRUCTURES FACING EACH OTHER ALONG BOTH SIDES OF THE NARROW STREET. - 208 Vine Street (House), 208 Vine Street, La Grange, Troup County, GA

Transforming growth factor-{beta}-inducible phosphorylation of Smad3.

PubMed

Wang, Guannan; Matsuura, Isao; He, Dongming; Liu, Fang

2009-04-10

Smad proteins transduce the transforming growth factor-beta (TGF-beta) signal at the cell surface into gene regulation in the nucleus. Upon TGF-beta treatment, the highly homologous Smad2 and Smad3 are phosphorylated by the TGF-beta receptor at the SSXS motif in the C-terminal tail. Here we show that in addition to the C-tail, three (S/T)-P sites in the Smad3 linker region, Ser(208), Ser(204), and Thr(179) are phosphorylated in response to TGF-beta. The linker phosphorylation peaks at 1 h after TGF-beta treatment, behind the peak of the C-tail phosphorylation. We provide evidence suggesting that the C-tail phosphorylation by the TGF-beta receptor is necessary for the TGF-beta-induced linker phosphorylation. Although the TGF-beta receptor is necessary for the linker phosphorylation, the receptor itself does not phosphorylate these sites. We further show that ERK is not responsible for TGF-beta-dependent phosphorylation of these three sites. We show that GSK3 accounts for TGF-beta-inducible Ser(204) phosphorylation. Flavopiridol, a pan-CDK inhibitor, abolishes TGF-beta-induced phosphorylation of Thr(179) and Ser(208), suggesting that the CDK family is responsible for phosphorylation of Thr(179) and Ser(208) in response to TGF-beta. Mutation of the linker phosphorylation sites to nonphosphorylatable residues increases the ability of Smad3 to activate a TGF-beta/Smad-target gene as well as the growth-inhibitory function of Smad3. Thus, these observations suggest that TGF-beta-induced phosphorylation of Smad3 linker sites inhibits its antiproliferative activity.

A 6.1 s isomer and rotational bands in $sup 192$Os

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pakkanen, A.; Heikkinen, D.W.

A 6.1 plus or minus 0.2 s activity has been observed when natural Os targets were bombarded with 14.5 MeV neutrons. The activity is assigned to the decay of a high-spin isomer in /sup 192/Os at 2015.4 keV, which is depopulated by M2 and E3 transitions. Singles and coincidence gamma -ray spectra have allowed the identification of seven new states in /sup 192/Os. Several of these levels have been placed in either the ground- state or gamma -vibrational bands, which are strongly mixed. Excitation energies, B(E2) ratios for these bands are compared with different theoretical models. (auth) It is shownmore » that, if one uses single-particle energies from experiment and a delta residual interaction, it is not possible to obtain the energy of the giant dipole and spurious states of /sup 208/Pb, and at the same time obtain reasonable results for the low-lying two- particle spectra of /sup 210/Pb or /sup 210/Po. Related to the above problem, the isobaric analog state of /sup 208/Pb (in /sup 208/Bi) comes much too low in calculations using realistic interactions. It is noted that the above difficulties can be overcome, phenomenologically at least, by adding to the effective interaction some longrange repulsive components. The Bansal- French and the Schiffer interactions are examples of these; however, the dipole--dipole component of the Schiffer interaction gives much too large a splitting between the dipole state and spurious state. (auth)« less

Atmospherically deposited trace metals from bulk mineral concentrate port operations.

PubMed

Taylor, Mark Patrick

2015-05-15

Although metal exposures in the environment have declined over the last two decades, certain activities and locations still present a risk of harm to human health. This study examines environmental dust metal and metalloid hazards (arsenic, cadmium, lead and nickel) associated with bulk mineral transport, loading and unloading port operations in public locations and children's playgrounds in the inner city of Townsville, northern Queensland. The mean increase in lead on post-play hand wipes (965 μg/m(2)/day) across all sites was more than 10-times the mean pre-play loadings (95 μg/m(2)/day). Maximum loading values after a 10-minute play period were 3012 μg/m(2), more than seven times the goal of 400 μg/m(2) used by the Government of Western Australia (2011). Maximum daily nickel post-play hand loadings (404 μg/m(2)) were more than 26 times above the German Federal Immission Control Act 2002 annual benchmark of 15 μg/m(2)/day. Repeat sampling over the 5-day study period showed that hands and surfaces were re-contaminated daily from the deposition of metal-rich atmospheric dusts. Lead isotopic composition analysis of dust wipes ((208)Pb/(207)Pb and (206)Pb/(207)Pb) showed that surface dust lead was similar to Mount Isa type ores, which are exported through the Port of Townsville. While dust metal contaminant loadings are lower than other mining and smelting towns in Australia, they exceeded national and international benchmarks for environmental quality. The lessons from this study are clear - even where operations are considered acceptable by managing authorities, targeted assessment and monitoring can be used to evaluate whether current management practices are truly best practice. Reassessment can identify opportunities for improvement and maximum environmental and human health protection. Copyright © 2015 Elsevier B.V. All rights reserved.

Case-only gene-environment interaction between ALAD tagSNPs and occupational lead exposure in prostate cancer.

PubMed

Neslund-Dudas, Christine; Levin, Albert M; Rundle, Andrew; Beebe-Dimmer, Jennifer; Bock, Cathryn H; Nock, Nora L; Jankowski, Michelle; Datta, Indrani; Krajenta, Richard; Dou, Q Ping; Mitra, Bharati; Tang, Deliang; Rybicki, Benjamin A

2014-05-01

Black men have historically had higher blood lead levels than white men in the U.S. and have the highest incidence of prostate cancer in the world. Inorganic lead has been classified as a probable human carcinogen. Lead (Pb) inhibits delta-aminolevulinic acid dehydratase (ALAD), a gene recently implicated in other genitourinary cancers. The ALAD enzyme is involved in the second step of heme biosynthesis and is an endogenous inhibitor of the 26S proteasome, a master system for protein degradation and a current target of cancer therapy. Using a case-only study design, we assessed potential gene-environment (G × E) interactions between lifetime occupational Pb exposure and 11 tagSNPs within ALAD in black (N = 260) and white (N = 343) prostate cancer cases. Two ALAD tagSNPs in high linkage disequilibrium showed significant interaction with high Pb exposure among black cases (rs818684 interaction odds ratio or IOR = 2.73, 95% CI 1.43-5.22, P = 0.002; rs818689 IOR = 2.20, 95% CI 1.15-4.21, P = 0.017) and an additional tagSNP, rs2761016, showed G × E interaction with low Pb exposure (IOR = 2.08, 95% CI 1.13-3.84, P = 0.019). Further, the variant allele of rs818684 was associated with a higher Gleason grade in those with high Pb exposure among both blacks (OR 3.96, 95% CI 1.01-15.46, P = 0.048) and whites (OR 2.95, 95% CI 1.18-7.39, P = 0.020). Genetic variation in ALAD may modify associations between Pb and prostate cancer. Additional studies of ALAD, Pb, and prostate cancer are warranted and should include black men. Prostate 74:637-646, 2014. © 2014 Wiley Periodicals, Inc. © 2014 Wiley Periodicals, Inc.

Historical reconstruction of atmospheric lead pollution in central Yunnan province, southwest China: an analysis based on lacustrine sedimentary records.

PubMed

Liu, Enfeng; Zhang, Enlou; Li, Kai; Nath, Bibhash; Li, Yanling; Shen, Ji

2013-12-01

Atmospheric lead (Pb) pollution during the last century in central Yunnan province, one of the largest non-ferrous metal production centers in China, was reconstructed using sediment cores collected from Fuxian and Qingshui Lakes. Lead concentrations and isotopic ratios ((207)Pb/(206)Pb and (208)Pb/(206)Pb) were measured in sediment cores from both lakes. The operationally defined chemical fractions of Pb in sediment core from Fuxian Lake were determined by the optimized BCR procedure. The chronology of the cores was reconstructed using (210)Pb and (137)Cs dating methods. Similar three-phase variations in isotopic ratios and enrichment factors of Pb were observed in the sediment cores from both lakes. Before the 1950s, the sediment data showed low (207)Pb/(206)Pb and (208)Pb/(206)Pb ratios and enrichment factors (EFs=~1), indicating that the sedimentary Pb was predominantly of lithogenic origin. However, these indices were increased gradually between the 1950s and the mid-1980s, implying an atmospheric Pb deposition. The EFs and isotopic ratios of Pb reached their peak during recent years, indicating aggravating atmospheric Pb pollution. The average anthropogenic Pb fluxes since the mid-1980s were estimated to be 0.032 and 0.053 g m(-2) year(-1) recorded in Fuxian and Qingshui cores, respectively. The anthropogenic Pb was primarily concentrated in the reducible fraction. Combining the results of Pb isotopic compositions and chemical speciations in the sediment cores and in potential sources, we deduced that recent aggravating atmospheric Pb pollution in central Yunnan province should primarily be attributed to regional emissions from non-ferrous metal production industries.

Field isotopic study of lead fate and compartmentalization in earthworm-soil-metal particle systems for highly polluted soil near Pb recycling factory.

PubMed

Goix, Sylvaine; Mombo, Stéphane; Schreck, Eva; Pierart, Antoine; Lévêque, Thibaut; Deola, Frédéric; Dumat, Camille

2015-11-01

Earthworms are important organisms in soil macrofauna and play a key role in soil functionality, and consequently in terrestrial ecotoxicological risk assessments. Because they are frequently observed in soils strongly polluted by metals, the influence of earthworm bioturbation on Pb fate could therefore be studied through the use of Pb isotopes. Total Pb concentrations and isotopic composition ((206)Pb, (207)Pb and (208)Pb) were then measured in earthworms, casts and bulk soils sampled at different distance from a lead recycling factory. Results showed decreasing Pb concentrations with the distance from the factory whatever the considered matrix (bulk soils, earthworm bodies or cast samples) with higher concentrations in bulk soils than in cast samples. The bivariate plot (208)Pb/(206)Pb ratios versus (206)Pb/(207)Pb ratios showed that all samples can be considered as a linear mixing between metallic process particulate matter (PM) and geochemical Pb background. Calculated anthropogenic fraction of Pb varied between approximately 84% and 100%. Based on Pb isotopic signatures, the comparison between casts, earthworms and bulk soils allowed to conclude that earthworms preferentially ingest the anthropogenic lead fraction associated with coarse soil organic matter. Actually, soil organic matter was better correlated with Pb isotopic ratios than with Pb content in soils. The proposed hypothesis is therefore a decrease of soil organic matter turnover due to Pb pollution with consequences on Pb distribution in soils and earthworm exposure. Finally, Pb isotopes analysis constitutes an efficient tool to study the influence of earthworm bioturbation on Pb cycle in polluted soils. Copyright © 2015 Elsevier Ltd. All rights reserved.

48 CFR 208.7304 - Refined precious metals.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Refined precious metals... Government-Owned Precious Metals 208.7304 Refined precious metals. See PGI 208.7304 for a list of refined precious metals managed by DSCP. [71 FR 39005, July 11, 2006] ...

48 CFR 208.7304 - Refined precious metals.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Refined precious metals... Government-Owned Precious Metals 208.7304 Refined precious metals. See PGI 208.7304 for a list of refined precious metals managed by DSCP. [71 FR 39005, July 11, 2006] ...

44 CFR 208.25 - Obsolete equipment.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Obsolete equipment. 208.25... Cooperative Agreements § 208.25 Obsolete equipment. (a) The Assistant Administrator will periodically identify obsolete items on the Equipment Cache List and provide such information to Sponsoring Agencies. (b) Neither...

31 CFR 208.10 - Reservation of rights.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Reservation of rights. 208.10 Section 208.10 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL AGENCY...

31 CFR 208.6 - General account requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false General account requirements. 208.6 Section 208.6 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL AGENCY...

12 CFR 208.35 - Qualification requirements for transactions in certain securities. [Reserved

Code of Federal Regulations, 2010 CFR

2010-01-01

... requirements for transactions in certain securities. [Reserved] ... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Qualification requirements for transactions in certain securities. [Reserved] 208.35 Section 208.35 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF...

22 CFR 208.860 - What factors may influence the debarring official's decision?

Code of Federal Regulations, 2010 CFR

2010-04-01

... not necessarily determinative of your present responsibility. In making a debarment decision, the... official's decision? 208.860 Section 208.860 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT... debarring official's decision? This section lists the mitigating and aggravating factors that the debarring...

44 CFR 208.23 - Allowable costs under Preparedness Cooperative Agreements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Allowable costs under Preparedness Cooperative Agreements. 208.23 Section 208.23 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE NATIONAL URBAN SEARCH AND...

40 CFR 240.208-2 - Recommended procedures: Design.

Code of Federal Regulations, 2010 CFR

2010-07-01

....208-2 Section 240.208-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures... allow for removal from the site of residue or other solids in a manner that protects the environment. ...

45 CFR 144.208 - Deadlines for submission of reports.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Section 144.208 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS REQUIREMENTS RELATING TO HEALTH INSURANCE COVERAGE Source: § 144.208 Deadlines for... care insurance policies issued to individuals or individuals under group coverage specified in § 144...

44 CFR 208.52 - Reimbursement procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Reimbursement procedures. 208... Reimbursement Claims and Appeals § 208.52 Reimbursement procedures. (a) General. A Sponsoring Agency must present a claim for reimbursement to DHS in such manner as the Assistant Administrator specifies . (b...

31 CFR 208.9 - Compliance.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false Compliance. 208.9 Section 208.9 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT... Compliance. (a) Treasury will monitor agencies' compliance with this part. Treasury may require agencies to...

31 CFR 208.9 - Compliance.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Compliance. 208.9 Section 208.9 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT... Compliance. (a) Treasury will monitor agencies' compliance with this part. Treasury may require agencies to...

30 CFR 70.208 - Bimonthly sampling; designated areas.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Bimonthly sampling; designated areas. 70.208... SAFETY AND HEALTH MANDATORY HEALTH STANDARDS-UNDERGROUND COAL MINES Sampling Procedures § 70.208 Bimonthly sampling; designated areas. (a) Each operator shall take one valid respirable dust sample from...

30 CFR 70.208 - Bimonthly sampling; designated areas.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Bimonthly sampling; designated areas. 70.208... SAFETY AND HEALTH MANDATORY HEALTH STANDARDS-UNDERGROUND COAL MINES Sampling Procedures § 70.208 Bimonthly sampling; designated areas. (a) Each operator shall take one valid respirable dust sample from...

45 CFR 400.208 - Claims involving family units which include both refugees and nonrefugees.

Code of Federal Regulations, 2010 CFR

2010-10-01

... refugees and nonrefugees. 400.208 Section 400.208 Public Welfare Regulations Relating to Public Welfare OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Federal Funding Federal Funding for Expenditures for Determining...

31 CFR 208.11 - Accounts for disaster victims.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Accounts for disaster victims. 208.11 Section 208.11 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL AGENCY...

21 CFR 211.208 - Drug product salvaging.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 4 2014-04-01 2014-04-01 false Drug product salvaging. 211.208 Section 211.208 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR FINISHED PHARMACEUTICALS Returned and Salvaged Drug...

21 CFR 211.208 - Drug product salvaging.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 4 2013-04-01 2013-04-01 false Drug product salvaging. 211.208 Section 211.208 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR FINISHED PHARMACEUTICALS Returned and Salvaged Drug...

21 CFR 211.208 - Drug product salvaging.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 4 2011-04-01 2011-04-01 false Drug product salvaging. 211.208 Section 211.208 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR FINISHED PHARMACEUTICALS Returned and Salvaged Drug...

21 CFR 211.208 - Drug product salvaging.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 4 2012-04-01 2012-04-01 false Drug product salvaging. 211.208 Section 211.208 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR FINISHED PHARMACEUTICALS Returned and Salvaged Drug...

31 CFR 800.208 - Critical infrastructure.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Critical infrastructure. 800.208..., AND TAKEOVERS BY FOREIGN PERSONS Definitions § 800.208 Critical infrastructure. The term critical infrastructure means, in the context of a particular covered transaction, a system or asset, whether physical or...

31 CFR 800.208 - Critical infrastructure.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Critical infrastructure. 800.208..., AND TAKEOVERS BY FOREIGN PERSONS Definitions § 800.208 Critical infrastructure. The term critical infrastructure means, in the context of a particular covered transaction, a system or asset, whether physical or...

31 CFR 800.208 - Critical infrastructure.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Critical infrastructure. 800.208..., AND TAKEOVERS BY FOREIGN PERSONS Definitions § 800.208 Critical infrastructure. The term critical infrastructure means, in the context of a particular covered transaction, a system or asset, whether physical or...

31 CFR 800.208 - Critical infrastructure.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Critical infrastructure. 800.208..., AND TAKEOVERS BY FOREIGN PERSONS Definitions § 800.208 Critical infrastructure. The term critical infrastructure means, in the context of a particular covered transaction, a system or asset, whether physical or...

44 CFR 208.10 - Other regulations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Other regulations. 208.10 Section 208.10 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF... Other regulations. The following provisions of title 44 CFR, Chapter I also apply to the program in this...

44 CFR 208.10 - Other regulations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Other regulations. 208.10 Section 208.10 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF... Other regulations. The following provisions of title 44 CFR, Chapter I also apply to the program in this...

23 CFR 636.208 - May I use my existing prequalification procedures with design-build contracts?

Code of Federal Regulations, 2010 CFR

2010-04-01

... design-build contracts? 636.208 Section 636.208 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS DESIGN-BUILD CONTRACTING Selection Procedures, Award Criteria... use your existing prequalification procedures for either construction or engineering design firms as a...

23 CFR 810.208 - Action by the Federal Highway Administrator.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 23 Highways 1 2014-04-01 2014-04-01 false Action by the Federal Highway Administrator. 810.208 Section 810.208 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PUBLIC TRANSPORTATION MASS TRANSIT AND SPECIAL USE HIGHWAY PROJECTS Making Highway Rights-of-Way Available for Mass...

23 CFR 810.208 - Action by the Federal Highway Administrator.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 23 Highways 1 2013-04-01 2013-04-01 false Action by the Federal Highway Administrator. 810.208 Section 810.208 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PUBLIC TRANSPORTATION MASS TRANSIT AND SPECIAL USE HIGHWAY PROJECTS Making Highway Rights-of-Way Available for Mass...

23 CFR 810.208 - Action by the Federal Highway Administrator.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 23 Highways 1 2012-04-01 2012-04-01 false Action by the Federal Highway Administrator. 810.208 Section 810.208 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PUBLIC TRANSPORTATION MASS TRANSIT AND SPECIAL USE HIGHWAY PROJECTS Making Highway Rights-of-Way Available for Mass...

5 CFR 178.208 - Applicability of general procedures.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Applicability of general procedures. 178.208 Section 178.208 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS... Applicability of general procedures. When not in conflict with this subpart, the provisions of subpart A of this...

γ-ray spectroscopy of 209Tl

DOE PAGES

Amro, B. M. S.; Lister, C. J.; McCutchan, E. A.; ...

2017-01-30

Here, states in 209TI were populated using a multi-nucleon transfer reaction with a 136Xe beam impinging on a thick 208Pb target at E = 785 MeV. The beam was pulsed at 825 ns intervals in order to perform isomer decay spectroscopy. The known J π = 17/2 + isomer in 209TI was located at 1228(4) keV and measured to have a half-life of T 1/2 = 146(10) ns. A second isomer with J π = 13/2 + were found to have T 1/2 = 14(5) ns.

21 CFR 211.208 - Drug product salvaging.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Drug product salvaging. 211.208 Section 211.208 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS... natural disasters, fires, accidents, or equipment failures shall not be salvaged and returned to the...

44 CFR 208.38 - Reimbursement for re-supply and logistics costs incurred during Activation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... this subpart, DHS will not reimburse costs incurred for re-supply and logistical support during... and logistics costs incurred during Activation. 208.38 Section 208.38 Emergency Management and...-supply and logistics costs incurred during Activation. With the exception of emergency procurement...

22 CFR 208.215 - Which nonprocurement transactions are not covered transactions?

Code of Federal Regulations, 2010 CFR

2010-04-01

... transactions: (a) A direct award to— (1) A foreign government or foreign governmental entity; (2) A public international organization; (3) An entity owned (in whole or in part) or controlled by a foreign government; or... covered transactions? 208.215 Section 208.215 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT...

31 CFR 208.3 - Payment by electronic funds transfer.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Payment by electronic funds transfer. 208.3 Section 208.3 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL AGENCY...

31 CFR 208.5 - Availability of the ETA SM.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Availability of the ETA SM. 208.5 Section 208.5 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL AGENCY...

44 CFR 208.1 - Purpose and scope of this part.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Purpose and scope of this part. 208.1 Section 208.1 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY... Rescue Response System. (b) Scope. This part applies to Sponsoring Agencies and other participants in the...

44 CFR 208.1 - Purpose and scope of this part.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Purpose and scope of this part. 208.1 Section 208.1 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY... Rescue Response System. (b) Scope. This part applies to Sponsoring Agencies and other participants in the...

44 CFR 208.1 - Purpose and scope of this part.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Purpose and scope of this part. 208.1 Section 208.1 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY... Rescue Response System. (b) Scope. This part applies to Sponsoring Agencies and other participants in the...

24 CFR 115.208 - Procedures for renewal of certification.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 1 2013-04-01 2013-04-01 false Procedures for renewal of certification. 115.208 Section 115.208 Housing and Urban Development Regulations Relating to Housing and Urban Development OFFICE OF ASSISTANT SECRETARY FOR EQUAL OPPORTUNITY, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT...

24 CFR 115.208 - Procedures for renewal of certification.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Procedures for renewal of certification. 115.208 Section 115.208 Housing and Urban Development Regulations Relating to Housing and Urban Development OFFICE OF ASSISTANT SECRETARY FOR EQUAL OPPORTUNITY, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT...

24 CFR 115.208 - Procedures for renewal of certification.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 1 2014-04-01 2014-04-01 false Procedures for renewal of certification. 115.208 Section 115.208 Housing and Urban Development Regulations Relating to Housing and Urban Development OFFICE OF ASSISTANT SECRETARY FOR EQUAL OPPORTUNITY, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT...

24 CFR 115.208 - Procedures for renewal of certification.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false Procedures for renewal of certification. 115.208 Section 115.208 Housing and Urban Development Regulations Relating to Housing and Urban Development OFFICE OF ASSISTANT SECRETARY FOR EQUAL OPPORTUNITY, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT...

24 CFR 115.208 - Procedures for renewal of certification.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Procedures for renewal of certification. 115.208 Section 115.208 Housing and Urban Development Regulations Relating to Housing and Urban Development OFFICE OF ASSISTANT SECRETARY FOR EQUAL OPPORTUNITY, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT...

5 CFR 362.208 - Resignation, termination, reduction in force, and appeal rights.

Code of Federal Regulations, 2010 CFR

2010-01-01

... force, and appeal rights. 362.208 Section 362.208 Administrative Personnel OFFICE OF PERSONNEL... Resignation, termination, reduction in force, and appeal rights. (a) Resignation. A Fellow or Senior Fellow... Senior Fellow is terminated for this or any reason. (c) Reduction in force. Fellows and Senior Fellows...

42 CFR 3.208 - Continued protection of patient safety work product.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Continued protection of patient safety work product. 3.208 Section 3.208 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS PATIENT SAFETY ORGANIZATIONS AND PATIENT SAFETY WORK PRODUCT Confidentiality and...

12 CFR 208.1 - Authority, purpose, and scope.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 208.1 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM MEMBERSHIP OF STATE BANKING INSTITUTIONS IN THE FEDERAL RESERVE SYSTEM (REGULATION H) General Membership and Branching Requirements § 208.1 Authority, purpose, and scope. (a) Authority. Subpart A of Regulation H (12...

10 CFR 1707.208 - Restrictions that apply to released records.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Restrictions that apply to released records. 1707.208 Section 1707.208 Energy DEFENSE NUCLEAR FACILITIES SAFETY BOARD TESTIMONY BY DNFSB EMPLOYEES AND PRODUCTION OF OFFICIAL RECORDS IN LEGAL PROCEEDINGS Requests for Testimony and Production of Documents § 1707...

10 CFR 1707.208 - Restrictions that apply to released records.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Restrictions that apply to released records. 1707.208 Section 1707.208 Energy DEFENSE NUCLEAR FACILITIES SAFETY BOARD TESTIMONY BY DNFSB EMPLOYEES AND PRODUCTION OF OFFICIAL RECORDS IN LEGAL PROCEEDINGS Requests for Testimony and Production of Documents § 1707...

10 CFR 1707.208 - Restrictions that apply to released records.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Restrictions that apply to released records. 1707.208 Section 1707.208 Energy DEFENSE NUCLEAR FACILITIES SAFETY BOARD TESTIMONY BY DNFSB EMPLOYEES AND PRODUCTION OF OFFICIAL RECORDS IN LEGAL PROCEEDINGS Requests for Testimony and Production of Documents § 1707...

10 CFR 1707.208 - Restrictions that apply to released records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Restrictions that apply to released records. 1707.208 Section 1707.208 Energy DEFENSE NUCLEAR FACILITIES SAFETY BOARD TESTIMONY BY DNFSB EMPLOYEES AND PRODUCTION OF OFFICIAL RECORDS IN LEGAL PROCEEDINGS Requests for Testimony and Production of Documents § 1707...

10 CFR 1707.208 - Restrictions that apply to released records.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Restrictions that apply to released records. 1707.208 Section 1707.208 Energy DEFENSE NUCLEAR FACILITIES SAFETY BOARD TESTIMONY BY DNFSB EMPLOYEES AND PRODUCTION OF OFFICIAL RECORDS IN LEGAL PROCEEDINGS Requests for Testimony and Production of Documents § 1707...

41 CFR 105-64.208 - What special conditions apply to release of medical records?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What special conditions apply to release of medical records? 105-64.208 Section 105-64.208 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION...

41 CFR 105-64.208 - What special conditions apply to release of medical records?

Code of Federal Regulations, 2012 CFR

2012-01-01

... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false What special conditions apply to release of medical records? 105-64.208 Section 105-64.208 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION...

41 CFR 105-64.208 - What special conditions apply to release of medical records?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false What special conditions apply to release of medical records? 105-64.208 Section 105-64.208 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION...

41 CFR 105-64.208 - What special conditions apply to release of medical records?

Code of Federal Regulations, 2014 CFR

2014-01-01

... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false What special conditions apply to release of medical records? 105-64.208 Section 105-64.208 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION...

41 CFR 105-64.208 - What special conditions apply to release of medical records?

Code of Federal Regulations, 2011 CFR

2011-01-01

... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false What special conditions apply to release of medical records? 105-64.208 Section 105-64.208 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION...

24 CFR 3280.208 - Smoke alarm requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 5 2012-04-01 2012-04-01 false Smoke alarm requirements. 3280.208... URBAN DEVELOPMENT MANUFACTURED HOME CONSTRUCTION AND SAFETY STANDARDS Fire Safety § 3280.208 Smoke alarm requirements. (a) Labeling. Each smoke alarm required under paragraph (b) of this section must conform with the...

24 CFR 3280.208 - Smoke alarm requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 5 2013-04-01 2013-04-01 false Smoke alarm requirements. 3280.208... URBAN DEVELOPMENT MANUFACTURED HOME CONSTRUCTION AND SAFETY STANDARDS Fire Safety § 3280.208 Smoke alarm requirements. (a) Labeling. Each smoke alarm required under paragraph (b) of this section must conform with the...

24 CFR 3280.208 - Smoke alarm requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false Smoke alarm requirements. 3280.208... URBAN DEVELOPMENT MANUFACTURED HOME CONSTRUCTION AND SAFETY STANDARDS Fire Safety § 3280.208 Smoke alarm requirements. (a) Labeling. Each smoke alarm required under paragraph (b) of this section must conform with the...

24 CFR 3280.208 - Smoke alarm requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 5 2014-04-01 2014-04-01 false Smoke alarm requirements. 3280.208... URBAN DEVELOPMENT MANUFACTURED HOME CONSTRUCTION AND SAFETY STANDARDS Fire Safety § 3280.208 Smoke alarm requirements. Link to an amendment published at 78 FR 73982, Dec. 9, 2013. (a) Labeling. Each smoke alarm...

40 CFR 211.208 - Export provisions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Export provisions. 211.208 Section 211... PRODUCT NOISE LABELING Hearing Protective Devices § 211.208 Export provisions. (a) The outside of each package or container containing a hearing protective device intended solely for export must be so labeled...

24 CFR 1003.208 - Criteria for compliance with the primary objective.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Criteria for compliance with the primary objective. 1003.208 Section 1003.208 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN HOUSING...

7 CFR 3555.208 - Special requirements for manufactured homes.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 15 2014-01-01 2014-01-01 false Special requirements for manufactured homes. 3555.208... Property § 3555.208 Special requirements for manufactured homes. Loans may be guaranteed for manufactured homes if all the requirements in this section are met. (a) Eligible costs. In addition to the loan...

48 CFR 208.7000 - Scope of subpart.

Code of Federal Regulations, 2010 CFR

2010-10-01

... (commodity assignments are listed in PGI 208.7006); or (b) The Integrated Materiel Management Program (assignments are in DoD 4140.26-M, Defense Integrated Materiel Management Manual for Consumable Items). [56 FR... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Scope of subpart. 208.7000...

48 CFR 208.7000 - Scope of subpart.

Code of Federal Regulations, 2011 CFR

2011-10-01

... (commodity assignments are listed in PGI 208.7006); or (b) The Integrated Materiel Management Program (assignments are in DoD 4140.26-M, Defense Integrated Materiel Management Manual for Consumable Items). [56 FR... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Scope of subpart. 208.7000...

48 CFR 208.7000 - Scope of subpart.

Code of Federal Regulations, 2013 CFR

2013-10-01

... (commodity assignments are listed in PGI 208.7006); or (b) The Integrated Materiel Management Program (assignments are in DoD 4140.26-M, Defense Integrated Materiel Management Manual for Consumable Items). [56 FR... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Scope of subpart. 208.7000...

48 CFR 208.7000 - Scope of subpart.

Code of Federal Regulations, 2014 CFR

2014-10-01

... (commodity assignments are listed in PGI 208.7006); or (b) The Integrated Materiel Management Program (assignments are in DoD 4140.26-M, Defense Integrated Materiel Management Manual for Consumable Items). [56 FR... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Scope of subpart. 208.7000...

48 CFR 208.7000 - Scope of subpart.

Code of Federal Regulations, 2012 CFR

2012-10-01

... (commodity assignments are listed in PGI 208.7006); or (b) The Integrated Materiel Management Program (assignments are in DoD 4140.26-M, Defense Integrated Materiel Management Manual for Consumable Items). [56 FR... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Scope of subpart. 208.7000...

44 CFR 208.38 - Reimbursement for re-supply and logistics costs incurred during Activation.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Reimbursement for re-supply and logistics costs incurred during Activation. 208.38 Section 208.38 Emergency Management and...-supply and logistics costs incurred during Activation. With the exception of emergency procurement...

44 CFR 208.38 - Reimbursement for re-supply and logistics costs incurred during Activation.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Reimbursement for re-supply and logistics costs incurred during Activation. 208.38 Section 208.38 Emergency Management and...-supply and logistics costs incurred during Activation. With the exception of emergency procurement...

44 CFR 208.38 - Reimbursement for re-supply and logistics costs incurred during Activation.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Reimbursement for re-supply and logistics costs incurred during Activation. 208.38 Section 208.38 Emergency Management and...-supply and logistics costs incurred during Activation. With the exception of emergency procurement...

44 CFR 208.38 - Reimbursement for re-supply and logistics costs incurred during Activation.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Reimbursement for re-supply and logistics costs incurred during Activation. 208.38 Section 208.38 Emergency Management and...-supply and logistics costs incurred during Activation. With the exception of emergency procurement...

50 CFR 226.208 - Critical habitat for green turtle.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Critical habitat for green turtle. 226.208 Section 226.208 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC... green turtle. (a) Culebra Island, Puerto Rico—Waters surrounding the island of Culebra from the mean...

12 CFR 208.51 - Real estate lending standards.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 2 2011-01-01 2011-01-01 false Real estate lending standards. 208.51 Section... MEMBERSHIP OF STATE BANKING INSTITUTIONS IN THE FEDERAL RESERVE SYSTEM (REGULATION H) Real Estate Lending and Appraisal Standards § 208.51 Real estate lending standards. (a) Adoption of written policies. Each state...

12 CFR 208.51 - Real estate lending standards.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 2 2014-01-01 2014-01-01 false Real estate lending standards. 208.51 Section... MEMBERSHIP OF STATE BANKING INSTITUTIONS IN THE FEDERAL RESERVE SYSTEM (REGULATION H) Real Estate Lending and Appraisal Standards § 208.51 Real estate lending standards. (a) Adoption of written policies. Each state...

12 CFR 208.51 - Real estate lending standards.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 2 2013-01-01 2013-01-01 false Real estate lending standards. 208.51 Section... MEMBERSHIP OF STATE BANKING INSTITUTIONS IN THE FEDERAL RESERVE SYSTEM (REGULATION H) Real Estate Lending and Appraisal Standards § 208.51 Real estate lending standards. (a) Adoption of written policies. Each state...

12 CFR 208.51 - Real estate lending standards.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 2 2012-01-01 2012-01-01 false Real estate lending standards. 208.51 Section... MEMBERSHIP OF STATE BANKING INSTITUTIONS IN THE FEDERAL RESERVE SYSTEM (REGULATION H) Real Estate Lending and Appraisal Standards § 208.51 Real estate lending standards. (a) Adoption of written policies. Each state...

22 CFR 208.880 - What factors may influence the debarring official during reconsideration?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false What factors may influence the debarring official during reconsideration? 208.880 Section 208.880 Foreign Relations AGENCY FOR INTERNATIONAL... influence the debarring official during reconsideration? The debarring official may reduce or terminate your...

12 CFR 208.37 - Government securities sales practices.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Government securities sales practices. 208.37... Securities-Related Activities § 208.37 Government securities sales practices. (a) Scope. This subpart is applicable to state member banks that have filed notice as, or are required to file notice as, government...

12 CFR 208.37 - Government securities sales practices.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 2 2013-01-01 2013-01-01 false Government securities sales practices. 208.37... Securities-Related Activities § 208.37 Government securities sales practices. (a) Scope. This subpart is applicable to state member banks that have filed notice as, or are required to file notice as, government...

44 CFR 208.37 - Reimbursement for equipment and supply costs incurred during Activation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... and supply costs incurred during Activation. 208.37 Section 208.37 Emergency Management and Assistance... and supply costs incurred during Activation. (a) Allowable costs. DHS will reimburse costs incurred for the emergency procurement of equipment and supplies in the number, type, and up to the cost...

8 CFR 208.20 - Determining if an asylum application is frivolous.

Code of Federal Regulations, 2010 CFR

2010-01-01

... frivolous. 208.20 Section 208.20 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION... immigration judge or the Board of Immigration Appeals specifically finds that the alien knowingly filed a... material elements is deliberately fabricated. Such finding shall only be made if the immigration judge or...

27 CFR 555.208 - Construction of type 2 magazines.

Code of Federal Regulations, 2010 CFR

2010-04-01

... magazines. 555.208 Section 555.208 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO... Construction of type 2 magazines. A type 2 magazine is a box, trailer, semitrailer, or other mobile facility. (a) Outdoor magazines—(1) General. Outdoor magazines are to be bullet-resistant, fire-resistant...

44 CFR 208.2 - Definitions of terms used in this part.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Definitions of terms used in this part. 208.2 Section 208.2 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY... defined term unless such capitalization results from the application of standard capitalization or style...

37 CFR 41.208 - Content of substantive and responsive motions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Content of substantive and responsive motions. 41.208 Section 41.208 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE PRACTICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Patent...

37 CFR 41.208 - Content of substantive and responsive motions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Content of substantive and responsive motions. 41.208 Section 41.208 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE PRACTICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Patent...

12 CFR 208.51 - Real estate lending standards.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Real estate lending standards. 208.51 Section... MEMBERSHIP OF STATE BANKING INSTITUTIONS IN THE FEDERAL RESERVE SYSTEM (REGULATION H) Real Estate Lending and Appraisal Standards § 208.51 Real estate lending standards. (a) Adoption of written policies. Each state...

19 CFR 208.7 - Determinations and reports.

Code of Federal Regulations, 2011 CFR

2011-04-01

... its reports to the President by September 25, 2007, with respect to petitions received on or before... separate views by members of the Commission regarding such determinations. (d) Public version of report... 19 Customs Duties 3 2011-04-01 2011-04-01 false Determinations and reports. 208.7 Section 208.7...

24 CFR 92.208 - Eligible community housing development organization (CHDO) operating expense and capacity...

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Eligible community housing development organization (CHDO) operating expense and capacity building costs. 92.208 Section 92.208 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development HOME...

27 CFR 41.208 - Maintenance and retention of records and reports.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Maintenance and retention of records and reports. 41.208 Section 41.208 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO IMPORTATION OF TOBACCO...

7 CFR 1160.208 - Powers of the Board.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 9 2010-01-01 2009-01-01 true Powers of the Board. 1160.208 Section 1160.208 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... of deposit of a bank that is a member of the Federal Reserve System, or in obligations fully...

44 CFR 208.45 - Advance of funds.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Agreements § 208.45 Advance of funds. At the time of Activation of a Task Force, the Task Force will develop... advance of funds will not include any costs for equipment purchase. ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Advance of funds. 208.45...

44 CFR 208.12 - Maximum Pay Rate Table.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Maximum Pay Rate Table. 208... § 208.12 Maximum Pay Rate Table. (a) Purpose. This section establishes the process for creating and updating the Maximum Pay Rate Table (Table), and the Table's use to reimburse Affiliated Personnel (Task...

50 CFR 665.208 - Protected species conservation.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 50 Wildlife and Fisheries 13 2013-10-01 2013-10-01 false Protected species conservation. 665.208... Fisheries § 665.208 Protected species conservation. The Regional Administrator may change the size of the protected species study zones defined in § 665.201 of this subpart: (a) If the Regional Administrator...

50 CFR 665.208 - Protected species conservation.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Protected species conservation. 665.208... Fisheries § 665.208 Protected species conservation. The Regional Administrator may change the size of the protected species study zones defined in § 665.201 of this subpart: (a) If the Regional Administrator...

50 CFR 665.208 - Protected species conservation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Protected species conservation. 665.208... Fisheries § 665.208 Protected species conservation. The Regional Administrator may change the size of the protected species study zones defined in § 665.201 of this subpart: (a) If the Regional Administrator...

50 CFR 665.208 - Protected species conservation.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 50 Wildlife and Fisheries 13 2012-10-01 2012-10-01 false Protected species conservation. 665.208... Fisheries § 665.208 Protected species conservation. The Regional Administrator may change the size of the protected species study zones defined in § 665.201 of this subpart: (a) If the Regional Administrator...

50 CFR 665.208 - Protected species conservation.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 50 Wildlife and Fisheries 13 2014-10-01 2014-10-01 false Protected species conservation. 665.208... Fisheries § 665.208 Protected species conservation. The Regional Administrator may change the size of the protected species study zones defined in § 665.201 of this subpart: (a) If the Regional Administrator...

42 CFR 57.208 - Health professions student loan promissory note and disclosure requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Health professions student loan promissory note and disclosure requirements. 57.208 Section 57.208 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR CONSTRUCTION OF TEACHING FACILITIES, EDUCATIONAL IMPROVEMENTS...

Coupled-channels analyses for 9,11Li + 208Pb fusion reactions with multi-neutron transfer couplings

NASA Astrophysics Data System (ADS)

Choi, Ki-Seok; Cheoun, Myung-Ki; So, W. Y.; Hagino, K.; Kim, K. S.

2018-05-01

We discuss the role of two-neutron transfer processes in the fusion reaction of the 9,11Li + 208Pb systems. We first analyze the 9Li + 208Pb reaction by taking into account the coupling to the 7Li + 210Pb channel. To this end, we assume that two neutrons are directly transferred to a single effective channel in 210Pb and solve the coupled-channels equations with the two channels. By adjusting the coupling strength and the effective Q-value, we successfully reproduce the experimental fusion cross sections for this system. We then analyze the 11Li + 208Pb reaction in a similar manner, that is, by taking into account three effective channels with 11Li + 208Pb, 9Li + 210Pb, and 7Li + 212Pb partitions. In order to take into account the halo structure of the 11Li nucleus, we construct the potential between 11Li and 208Pb with a double folding procedure, while we employ a Woods-Saxon type potential with the global Akyüz-Winther parameters for the other channels. Our calculation indicates that the multiple two-neutron transfer process plays a crucial role in the 11Li + 208Pb fusion reaction at energies around the Coulomb barrier.

Lead Isotopic Source Signatures for Rains and River Waters in Taiwan

NASA Astrophysics Data System (ADS)

You, C.; Cheng, M.; Lee, M.; Lin, F.

2002-12-01

Lead isotopic compositions and Pb contents in rains and river waters are sensitive proxies for air-pollutant sources and their transport processes. We have collected more than 100 wet precipitations between 1998 and 2001 at Peng-Chia Yu, an offshore island in northern Taiwan, and two other cities, Taichung and Tainan, located at central and southern Taiwan. Additional 14 river waters collected along the Er-Ren-Shi River, Tainan were investigated for systematic comparison. All collected samples were analyzed for major ions (i.e., Cl, Na, Mg, Ca, SO4, NO3 and NH4) by ion chromatography, trace elements and Pb isotopes by ICP-MS (Element II) installed at NCKU. The Peng-Chia Yu rains show large seasonal variation in major ions where Na and Cl are much higher in the winter season. Significant industrial contributions of SO4, NH4 and nsCa are detected at Taichung and Tainan. Trace element results display a more complicated picture, suggesting mixing among seasalt, Asia continental dust, and atmospheric pollutant. These chemical data can be understood in terms of seasonal wind direction changes due to the Asian monsoon system. In winter, the northerly cold wind blow materials with high concentration of anthropogenic input (i.e., Pb and SO4) and dust source (i.e., Al and Ca) from the Asia continent. In contrast, the intertropical convergence zone (ITCZ) migrates northward and caused southwest monsoon prevail in the summer. The 208Pb/207Pb ratio shows consistent seasonal trends as that of Pb contents, possibly a result of mixing between Asia atmospheric sources and seasalt. For the Er-ren Shi River waters, Pb and Pb isotopic compositions vary systematically downstream. Pb concentrations decrease rapidly from 5200 ppt at upstream stations to a value of less than 50 ppt near the estuary whereas 208Pb/207Pb varied between 2.087 and 2.124. The 208Pb/206Pb vs. 1/Pb plot demonstrates a mixing trend between anthropogenic sources and seawater. These results demonstrate that Pb and Pb isotopes in rains and river waters can be used as useful tools for tracing air-borne pollutant sources and their transportation processes.

Role of shell corrections in the phenomenon of cluster radioactivity

NASA Astrophysics Data System (ADS)

Kaur, Mandeep; Singh, Bir Bikram; Sharma, Manoj K.

2018-05-01

The detailed investigation has been carried out to explore the role of shell corrections in the decay of various radioactive parent nuclei in trans-lead region, specifically, which lead to doubly magic 208Pb daughter nucleus through emission of clusters such as 14C, 18,20O, 22,24,26Ne, 28,30 Mg and 34S i. The fragmentation potential comprises of binding energies (BE), Coulomb potential (Vc) and nuclear or proximity potential (VP) of the decaying fragments (or clusters). It is relevant to mention here that the contributions of VLDM (T=0) and δU (T=0) in the BE have been analysed within the Strutinsky renormanlization procedure. In the framework of quantum mechanical fragmentation theory (QMFT), we have investigated the above mentioned cluster decays with and without inclusion of shell corrections in the fragmentation potential for spherical as well as non-compact oriented nuclei. We find that the experimentally observed clusters 14C, 18,20O, 22,24,26 Ne, 28,30 Mg and 34Si having doubly magic 208 Pb daughter nucleus are not strongly minimized, they do so only after the inclusion of shell corrections in the fragmentation potential. The nuclear structure information carried by the shell corrections have been explored via these calculations, within the collective clusterisation process of QMFT, in the study of ground state decay of radioactive nuclei. The role of different parts of fragmentation potentials such as VLDM, δU, Vc and Vp is dually analysed for better understanding of radioactive cluster decay.

50 CFR 223.208 - Corals.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Sanctuaries Act 16 U.S.C. 1431 et seq. NOAA, NOS Coral Reef Conservation Act 16 U.S.C. 6406 Commandant, U.S... Management; Coral Reef RestorationFL Statute § 390.0558 Florida Fish and Wildlife Conservation Commission... 50 Wildlife and Fisheries 10 2012-10-01 2012-10-01 false Corals. 223.208 Section 223.208 Wildlife...

50 CFR 223.208 - Corals.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Sanctuaries Act 16 U.S.C. 1431 et seq. NOAA, NOS Coral Reef Conservation Act 16 U.S.C. 6406 Commandant, U.S... Management; Coral Reef RestorationFL Statute § 390.0558 Florida Fish and Wildlife Conservation Commission... 50 Wildlife and Fisheries 10 2014-10-01 2014-10-01 false Corals. 223.208 Section 223.208 Wildlife...

50 CFR 223.208 - Corals.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Sanctuaries Act 16 U.S.C. 1431 et seq. NOAA, NOS Coral Reef Conservation Act 16 U.S.C. 6406 Commandant, U.S... Management; Coral Reef RestorationFL Statute § 390.0558 Florida Fish and Wildlife Conservation Commission... 50 Wildlife and Fisheries 10 2013-10-01 2013-10-01 false Corals. 223.208 Section 223.208 Wildlife...

50 CFR 223.208 - Corals.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Act 16 U.S.C. 1431 et seq. NOAA, NOS Coral Reef Conservation Act 16 U.S.C. 6406 Commandant, U.S. Coast...; Coral Reef RestorationFL Statute § 390.0558 Florida Fish and Wildlife Conservation Commission Fish and... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Corals. 223.208 Section 223.208 Wildlife...

50 CFR 223.208 - Corals.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Sanctuaries Act 16 U.S.C. 1431 et seq. NOAA, NOS Coral Reef Conservation Act 16 U.S.C. 6406 Commandant, U.S... Management; Coral Reef RestorationFL Statute § 390.0558 Florida Fish and Wildlife Conservation Commission... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Corals. 223.208 Section 223.208 Wildlife...

7 CFR 400.208 - Term of the contract.

Code of Federal Regulations, 2010 CFR

2010-01-01

... writing to the other party that the contract is not to be renewed. Any breach of the contract, or failure... 7 Agriculture 6 2010-01-01 2010-01-01 false Term of the contract. 400.208 Section 400.208..., DEPARTMENT OF AGRICULTURE GENERAL ADMINISTRATIVE REGULATIONS Agency Sales and Service Contract-Standards for...

42 CFR 402.208 - Factors considered in determining whether to exclude, and the length of exclusion.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 2 2014-10-01 2014-10-01 false Factors considered in determining whether to exclude, and the length of exclusion. 402.208 Section 402.208 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CIVIL MONEY PENALTIES...

22 CFR 208.705 - What does the suspending official consider in issuing a suspension?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false What does the suspending official consider in issuing a suspension? 208.705 Section 208.705 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT... cause for suspension or from potential business relationships or involvement with a program of the...

40 CFR 124.208 - What are the opportunities for public comments and hearings on draft permit decisions?

Code of Federal Regulations, 2014 CFR

2014-07-01

... comments and hearings on draft permit decisions? 124.208 Section 124.208 Protection of Environment... the opportunities for public comments and hearings on draft permit decisions? (a) The public notice... your draft permit decision. This time is referred to as the public comment period. You must...