Systematic continuum-discretized coupled-channels calculations of total fusion for 6Li with targets 28Si, 59Co, 96Zr, 198Pt, and 209Bi: Effect of resonance states

NASA Astrophysics Data System (ADS)

Gómez Camacho, A.; Wang, Bing; Zhang, H. Q.

2018-05-01

Continuum discretized coupled-channel (CDCC) calculations of total fusion cross sections for reactions induced by the weakly bound nucleus 6Li with targets 28Si, 59Co, 96Zr, 198Pt, and 209Bi at energies around the Coulomb barrier are presented. In the cluster structure frame of 6Li→α +d , short-range absorption potentials are considered for the interactions between the α and d fragments with the targets. The effect of resonance (l =2 , Jπ=3+,2+,1+ ) and nonresonance states of 6Li on fusion is studied by using two approaches: (1) by omitting the resonance states from the full discretized CDCC breakup space and (2) by considering only the resonance subspace. A systematic analysis of the effect on fusion from resonance breakup couplings is carried out from light to heavy mass targets. Among other things, it is found that resonance breakup states produce strong repulsive polarization potentials that lead to fusion suppression. Couplings from nonresonance states give place to weak repulsive potentials at high energies; however, these become attractive for the heavier targets at low energies.

Reversal of chloroquine resistance in Plasmodium falciparum by CDR 87/209 and analogues.

PubMed

Walter, R D; Seth, M; Bhaduri, A P

1993-03-01

The spreading of resistance towards chloroquine has diminished its value as a potent and safe drug in malaria endemic areas. Recent reports on the reversal of chloroquine resistance in the malaria parasite Plasmodium falciparum in vitro and in vivo by verapamil, desipramine and other Ca(2+)-channel blockers and antidepressants has initiated a strategy for chemotherapy by treatment with chloroquine in combination with a drug resistance modulator. Described here is a class of modulators of distinct structure which reverse chloroquine resistance in a different manner. Contrary to verapamil and desipramine, CDRI 87/209, the most potent compound of this new class and used as a chemical lead, did not restore chloroquine accumulation in the resistant parasites, thereby indicating that besides the proposed blockade of drug efflux other mechanisms are vulnerable targets for a chemotherapeutic approach towards drug resistance. Similar to the former modulators, CDRI 87/209 showed only weak intrinsic plasmodicidal activity and the increase of drug susceptibility was restricted to resistant plasmodia.

48 CFR 209.570-1 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., DEPARTMENT OF DEFENSE ACQUISITION PLANNING CONTRACTOR QUALIFICATIONS Organizational and Consultant Conflicts... clause at 252.209-7007, Prohibited Financial Interests for Lead System Integrators. See PGI 209.570-1 for...

48 CFR 209.570-3 - Procedures.

Code of Federal Regulations, 2014 CFR

2014-10-01

... out the use of contracted lead system integrator functions over the shortest period of time consistent... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Procedures. 209.570-3 Section 209.570-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM...

48 CFR 209.570-3 - Procedures.

Code of Federal Regulations, 2013 CFR

2013-10-01

... out the use of contracted lead system integrator functions over the shortest period of time consistent... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Procedures. 209.570-3 Section 209.570-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM...

48 CFR 209.570-3 - Procedures.

Code of Federal Regulations, 2012 CFR

2012-10-01

... out the use of contracted lead system integrator functions over the shortest period of time consistent... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Procedures. 209.570-3 Section 209.570-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM...

48 CFR 209.570-3 - Procedures.

Code of Federal Regulations, 2011 CFR

2011-10-01

... out the use of contracted lead system integrator functions over the shortest period of time consistent... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Procedures. 209.570-3 Section 209.570-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM...

Measurement of 208Pb(n ,γ )209Pb Maxwellian averaged neutron capture cross section

NASA Astrophysics Data System (ADS)

Weissman, L.; Tessler, M.; Arenshtam, A.; Eliyahu, I.; Halfon, S.; Guerrero, C.; Kaizer, B.; Kijel, D.; Kreisel, A.; Palchan, T.; Paul, M.; Perry, A.; Schimel, G.; Silverman, I.; Shor, A.; Tamim, N.; Vaintraub, S.

2017-07-01

The doubly magic 208Pb nucleus is a bottleneck at the termination of the s -process path due to its very low neutron capture cross section. This cross section is also important for the decomposition of s , r processes and U/Th radiogenic decay contributions to the Pb-Bi solar abundances. The 208Pb(n ,γ )209Pb cross section was measured at the Soreq Applied Research Accelerator Facility Phase I using an intense quasi-Maxwellian neutron source produced by irradiation of the liquid-lithium target with a 1.5-mA continuous-wave proton beam at 1.94 MeV. The cross section was measured by counting the β activity from the irradiated lead target. The measurement allowed us to evaluate the Maxwellian averaged cross section (MACS) at 30 keV obtaining a value of 0.33(2) mb. This has been compared with the earlier activation and time-of-flight measurements found in the literature. The MACS cross-sectional value of the 63Cu(n ,γ )64Cu reaction was determined in the same experiment and is compared to a recent published value.

Realizing the potential of the Actinium-225 radionuclide generator in targeted alpha-particle therapy applications

PubMed Central

Miederer, Matthias; Scheinberg, David A.; McDevitt, Michael R.

2013-01-01

Alpha particle-emitting isotopes have been proposed as novel cytotoxic agents for augmenting targeted therapy. Properties of alpha particle radiation such as their limited range in tissue of a few cell diameters and their high linear energy transfer leading to dense radiation damage along each alpha track are promising in the treatment of cancer, especially when single cells or clusters of tumor cells are targeted. Actinium-225 (225Ac) is an alpha particle-emitting radionuclide that generates 4 net alpha particle isotopes in a short decay chain to stable 209Bi, and as such can be described as an alpha particle nanogenerator. This article reviews the literature pertaining to the research, development, and utilization of targeted 225Ac to potently and specifically affect cancer. PMID:18514364

The bioavailability and adverse impacts of lead and decabromodiphenyl ether on soil microbial activities.

PubMed

Chen, Lei; Zhang, Wei; Zhang, Rong; Lin, Kuangfei; He, Lei; Wu, Liqun

2015-08-01

Lead (Pb) and decabromodiphenyl ether (BDE209) are the main pollutants at electronic waste (e-waste) recycling sites (EWRSs), and their potential toxic effects on soil organisms have received extensive attention. However, the impact on soil microorganisms of joint exposure to the two chemicals remains almost unknown. Therefore, indoor incubation tests were performed to explore the adverse impacts of Pb and BDE209 on soil microbial activities and chemical transformation for the first time. The results have demonstrated that BDE209 was barely degraded in all treated groups, indicating that the presence of Pb hardly affected BDE209 dissipation. The fractions analysis according to Tessier suggested that Pb gradually transformed towards more stable fractions in the slightly alkaline soil, thus reducing the bioavailability of Pb. Additionally, increased Pb doses caused significantly higher bioavailability (p < 0.05), and the same trend was clearly observed after simultaneous exposure to BDE209. Generally, single Pb or BDE209 exposure markedly inhibited (p < 0.05 or 0.01) soil microbial biomass C (C mic), while soil basal respiration (SBR) indicated the opposite response trend (inhibition or stimulation for BDE209 or Pb alone, respectively). Compared to the controls, Pb dramatically (p < 0.01) facilitated soil metabolic quotient (qCO2) during the incubation period. After joint exposure to Pb and BDE209, C mic generally declined with increasing exposure concentration, following certain dose-response relationships. However, SBR and qCO2 were highly significantly stimulated (p < 0.01), and more doses of Pb and BDE209 resulted in higher values. The results of these observations have provided a basic understanding of the potential ecological risk of Pb and BDE209 in soil at EWRSs.

Asymptotic and near-target direct breakup of 6Li and 7Li

NASA Astrophysics Data System (ADS)

Kalkal, Sunil; Simpson, E. C.; Luong, D. H.; Cook, K. J.; Dasgupta, M.; Hinde, D. J.; Carter, I. P.; Jeung, D. Y.; Mohanto, G.; Palshetkar, C. S.; Prasad, E.; Rafferty, D. C.; Simenel, C.; Vo-Phuoc, K.; Williams, E.; Gasques, L. R.; Gomes, P. R. S.; Linares, R.

2016-04-01

Background: Li,76 and 9Be are weakly bound against breakup into their cluster constituents. Breakup location is important for determining the role of breakup in above-barrier complete fusion suppression. Recent works have pointed out that experimental observables can be used to separate near-target and asymptotic breakup. Purpose: Our purpose is to distinguish near-target and asymptotic direct breakup of Li,76 in reactions with nuclei in different mass regions. Method: Charged particle coincidence measurements are carried out with pulsed Li,76 beams on 58Ni and 64Zn targets at sub-barrier energies and compared with previous measurements using 208Pb and 209Bi targets. A detector array providing a large angular coverage is used, along with time-of-flight information to give definitive particle identification of the direct breakup fragments. Results: In interactions of 6Li with 58Ni and 64Zn, direct breakup occurs only asymptotically far away from the target. However, in interactions with 208Pb and 209Bi, near-target breakup occurs in addition to asymptotic breakup. Direct breakup of 7Li into α -t is not observed in interactions with 58Ni and 64Zn. However, near-target dominated direct breakup was observed in measurements with 208Pb and 209Bi. A modified version of the Monte Carlo classical trajectory model code platypus, which explicitly takes into account lifetimes associated with unbound states, is used to simulate sub-barrier breakup reactions. Conclusions: Near-target breakup in interactions with Li,76 is an important mechanism only for the heavy targets 208Pb and 209Bi. There is insignificant near-target direct breakup of 6Li and no direct breakup of 7Li in reactions with 58Ni and 64Zn. Therefore, direct breakup is unlikely to suppress the above-barrier fusion cross section in reactions of Li,76 with 58Ni and 64Zn nuclei.

Effects of decabromodiphenyl ether on lead mobility and microbial toxicity in soil.

PubMed

Zhang, Wei; Chen, Lei; Zhang, Rong; Lin, Kuangfei

2015-03-01

Lead (Pb) and decabromodiphenyl ether (BDE209) are the main pollutants at e-waste recycling sites (EWRSs). Focus on joint toxicological effects of the two chemicals has increasingly gained a great amount of interest. Therefore, the lab study was performed to determine the Pb mobility and microbial toxicity in a Pb-polluted soil in the presence of BDE209 for the first time. The results showed that BDE209 was barely degraded and could elicit the combined effects with Pb exposure during the entire incubation period. The exchangeable (EXCH) and carbonates fractions of Pb were transformed to organic, Fe/Mn oxides and residual fractions, and the addition of an appropriate amount (100mgkg(-1)) of BDE209 facilitated the transformation compared with Pb alone. In addition, soil microbial biomass C (Cmic), soil basal respiration (SBR) and metabolic quotient (qCO2) increased in the beginning of the experiment and then declined with the incubation period extension, and BDE209 addition might cause notable different response relative to the control. Significant correlations between EXCH or mobility factor (MF) of Pb and SBR, Cmic, or qCO2 in soil treated with BDE209 can be clearly observed. Results of the observations provide a better understanding of ecotoxicological effects of Pb and BDE209 joint exposure on indigenous microorganisms in soil at EWRSs. Copyright © 2014 Elsevier Ltd. All rights reserved.

Transgenerational endocrine disruption and neurotoxicity in zebrafish larvae after parental exposure to binary mixtures of decabromodiphenyl ether (BDE-209) and lead.

PubMed

Chen, Lianguo; Wang, Xianfeng; Zhang, Xiaohua; Lam, Paul K S; Guo, Yongyong; Lam, James C W; Zhou, Bingsheng

2017-11-01

Polybrominated diphenyl ethers (PBDEs) and heavy metals are two key groups of electric and electronic equipment contaminants. Despite their co-occurrence in aquatic environments, their combined effects remain largely unknown, particularly under a chronic exposure regime. In the present study, adult zebrafish (Danio rerio) were exposed to environmentally relevant concentrations of BDE-209 and lead (Pb), or their binary mixtures, for 3 months. After chronic parental exposure, increased transfer of BDE-209 and Pb to the offspring eggs was activated in the coexposure groups, with BDE-197 being the predominant PBDE congener, indicating the dynamic metabolism of BDE-209 in parental zebrafish. In the presence of Pb, culturing the eggs in clean water until 5 days post-fertilization (dpf) further accelerated the debromination of BDE-209 towards BDE-197 in the offspring, caused by the preferential removal of bromine atoms at meta positions. BDE-209 and Pb combinations induced reproductive and thyroid endocrine disruption in adults, which resulted in an imbalanced deposition of hormones in the eggs. However, compared with single chemical exposure, the larval offspring at 5 dpf from the coexposure groups had reversed the adverse influences from maternal origin. In addition, the interaction between BDE-209 and Pb led to transgenerational developmental neurotoxicity in the larval offspring, where inhibited neuronal growth and neurotransmitter signaling, disorganized muscular assembly, and impaired visual function contributed to the observed neurobehavioral deficits. Overall, depending on specific biological events, the complex interaction between BDE-209 and Pb under chronic exposure resulted in significant alterations in their environmental fate and toxicological actions, thus complicating the accurate evaluation of ecological risks and constituting an unquantified threat to environmental safety. Copyright © 2017 Elsevier Ltd. All rights reserved.

γ-ray spectroscopy of 209Tl

DOE PAGES

Amro, B. M. S.; Lister, C. J.; McCutchan, E. A.; ...

2017-01-30

Here, states in 209TI were populated using a multi-nucleon transfer reaction with a 136Xe beam impinging on a thick 208Pb target at E = 785 MeV. The beam was pulsed at 825 ns intervals in order to perform isomer decay spectroscopy. The known J π = 17/2 + isomer in 209TI was located at 1228(4) keV and measured to have a half-life of T 1/2 = 146(10) ns. A second isomer with J π = 13/2 + were found to have T 1/2 = 14(5) ns.

Sci-Thur AM: YIS – 01: New technologies for astatine-211 targeted alpha therapy research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crawford, Jason; Yang, Hua; Schaffer, Paul

Purpose: The short-range, densely ionizing α-particles emitted by {sup 211}At (t{sub 1/2}=7.2h) are well suited for the treatment of diffuse microscopic disease, using cancer targeting biomolecules. {sup 211}At availability is limited by the rarity of α-cyclotrons required for standard production. Image-based dosimetry is also limited for {sup 211}At, which emits low intensity X-rays. Our goal was to leverage state-of-the-art infrastructure at TRIUMF to produce and evaluate two related isotopes, {sup 211}Rn (t{sub 1/2}=14.6h, 73% decay to {sup 211}At) as a generator for {sup 211}At, and {sup 209}At (t{sub 1/2}=5.4h, X-ray/gamma-ray emitter) as a novel 211At surrogate for preclinical imaging studies.more » Methods: Produced by spallation of uranium with 480 MeV protons, mass separated ion beams of short-lived francium isotopes were implanted into NaCl targets where {sup 211}Rn or {sup 209}At were produced by radioactive decay, in situ. {sup 211}Rn was transferred to dodecane from which {sup 211}At was efficiently extracted and evaluated for clinical applicability. High energy SPECT/CT was evaluated for measuring {sup 209}At activity distributions in mice and phantoms. Results: Our small scale {sup 211}Rn/{sup 211}At generator system provided high purity {sup 211}At samples. The methods are immediately scalable to the level of radioactivity required for in vivo experiments with {sup 211}At. {sup 209}At-based high energy SPECT imaging was determined suitable for pursuing image-based dosimetry in mouse tumour models. In the future, we will utilize quantitative {sup 209}At-SPECT for image-based dose calculations. Conclusion: These early studies provided a foundation for future endeavours with {sup 211}At-based α-therapy. Canada is now significantly closer to clinical targeted α-therapy of cancer.« less

50 CFR 300.209 - Alternative procedures for nations identified as having vessels engaged in shark catch that are...

Code of Federal Regulations, 2014 CFR

2014-10-01

... identified as having vessels engaged in shark catch that are not certified in this subpart. 300.209 Section... identified as having vessels engaged in shark catch that are not certified in this subpart. (a) These... not target or incidentally catch sharks, or were harvested by practices that— (1) Are comparable to...

50 CFR 300.209 - Alternative procedures for nations identified as having vessels engaged in shark catch that are...

Code of Federal Regulations, 2013 CFR

2013-10-01

... identified as having vessels engaged in shark catch that are not certified in this subpart. 300.209 Section... identified as having vessels engaged in shark catch that are not certified in this subpart. (a) These... not target or incidentally catch sharks, or were harvested by practices that— (1) Are comparable to...

Which colours are seen by the patient during cataract surgery? Results of an intraoperative interview.

PubMed

Wenzel, M; Schulze Schwering, M

2016-03-01

To discover what cataract patients see during phacoemulsification and if these light phenomena influence their anxiety levels during surgery. In all, 200 patients were interviewed intraoperatively at the Eye Hospital, Petrisberg, Trier, Germany. The quality of the visual experiences was described and if these were pleasant, neutral or unpleasant. Systemic sedation was noted. Among 200 patients (209 eyes): 88 were men (91 eyes; 44%) and 112 were women (118 eyes; 56%). Median age (years): men (71), women (70). Mean operating time was 8 min. 49/209 (23%) were not anxious before and during surgery. 110/209 (52%) were more anxious before than during surgery, 50/209 (24%) were still anxious during surgery, 27/209 (13%) got sedation with midazolam (1-5 mg). Colours in descending order seen: blue, red, pink, yellow, green, purple, turquois, and orange. The most dominant colour combination was red/blue. Structures were seen by 162/209 (78%). Most (61%) intraoperative visual experiences were pleasant, 38% were neutral, and 1% found them transiently unpleasant. Three patients felt blinded by the light of the operating microscope. The experience of colours and other light phenomena was pleasant for most patients during phacoemulsification under topical anaesthesia. They occur spontaneously when the patient is fixating on the operating light. They are not dependent on the individual or environment. Sedation only in 13%. Direct questioning for visual sensations by the operating surgeon may lead to less need for sedation and lead to less side effects for elderly and multimorbidity people postoperatively. The surgeon can use this knowledge to reassure patients during surgery.

Changes of lead speciation and microbial toxicity in soil treated with repeated Pb exposure in the presence of BDE209.

PubMed

Zhang, Rong; Zhang, Wei; Liu, Gao; Lin, Kuangfei; Fu, Rongbing

2016-03-01

Lead (Pb) and decabromodiphenyl ether (BDE209) are main pollutants at electric waste (e-waste) recycling sites (EWRSs), and their joint toxicological effects have received extensive attention. Frequently, soil pollution at EWRSs usually results from the occurrence of repeated single or multiple pollution events, with continuous impacts on soil microorganisms. Therefore, a laboratory incubation study was conducted to determine Pb bioavailability and microbial toxicity in repeated Pb-polluted soil in the presence of BDE209 for the first time. We evaluated the impacts of repetitive exposure trials on chemical fractions of Pb, and the results showed that repeated single Pb pollution event resulted in an increase of carbonates fraction of Pb, which was different from one-off single Pb exposure. Moreover, one-off Pb-treated groups exhibited higher I R (reduced partition index) values on day 30 and all treatments remained the same I R level at the end of incubation period. The parameters of microbial toxicity were well reflected by soil enzymes. During the entire incubation, the dehydrogenase and urease activities were significantly inhibited by Pb (P < 0.01), and BDE209 supply could weaken the adverse influence. Additionally, significant correlations between available or metastable Pb and the two soil enzymes were clearly observed (P < 0.05 or 0.01). Such observations would provide useful information for ecological effects of Pb and BDE209 at EWRSs.

Is decabromodiphenyl ether (BDE-209) a developmental neurotoxicant?

PubMed Central

Costa, Lucio G.; Giordano, Gennaro

2011-01-01

Polybrominated diphenyl ether (PBDE) flame retardants have become ubiquitous environmental pollutants. The relatively higher body burden in toddlers and children has reaised concern for their potential developmental neurotoxicity, which has been suggested by animal studies, in vitro experiments, and recent human epidemiological evidence. While lower brominated PBDEs have been banned in several countries, the fully brominated decaBDE (BDE-209) is still utilized, though manufacturers will discontinue production in the U.S.A. in 2013. The recent decision by the U.S. Environmental Protection Agency to base the Reference Dose (RfD) for BDE-209 on a developmental neurotoxicity study has generated some controversy. Because of its bulky configuration, BDE-209 is poorly absorbed and does not easily penetrate the cell wall. Its acute and chronic toxicities are relatively low, with the liver and the thyroid as the primary targets, though there is some evidence of carcinogenicity. A few animal studies have indicated that BDE-209 may cause developmental neurotoxicity, affecting motor and cognitive domains, as seen for other PBDEs. Limited in vivo and in vitro studies have also evidenced effects of BDE-209 on thyroid hormone homeostasis and direct effects on nervous cells, again similar to what found with other lower brominated PBDEs. In contrast, a recent developmental neurotoxicity study, carried out according to international guidelines, has provided no evidence of adverse effects on neurodevelopment, and this should be considered in a future re-evaluation of BDE-209. While estimated exposure to BDE-209 in children is believed to be several orders of magnitude below the most conservative RfD proposed by the USEPA, questions remain on the extent and relevance of BDE-209 metabolism to lower brominated PBDEs in the environment and in humans. PMID:21182867

The heritage of pathogen pressures and ancient demography in the human innate-immunity CD209/CD209L region.

PubMed

Barreiro, Luis B; Patin, Etienne; Neyrolles, Olivier; Cann, Howard M; Gicquel, Brigitte; Quintana-Murci, Lluís

2005-11-01

The innate immunity system constitutes the first line of host defense against pathogens. Two closely related innate immunity genes, CD209 and CD209L, are particularly interesting because they directly recognize a plethora of pathogens, including bacteria, viruses, and parasites. Both genes, which result from an ancient duplication, possess a neck region, made up of seven repeats of 23 amino acids each, known to play a major role in the pathogen-binding properties of these proteins. To explore the extent to which pathogens have exerted selective pressures on these innate immunity genes, we resequenced them in a group of samples from sub-Saharan Africa, Europe, and East Asia. Moreover, variation in the number of repeats of the neck region was defined in the entire Human Genome Diversity Panel for both genes. Our results, which are based on diversity levels, neutrality tests, population genetic distances, and neck-region length variation, provide genetic evidence that CD209 has been under a strong selective constraint that prevents accumulation of any amino acid changes, whereas CD209L variability has most likely been shaped by the action of balancing selection in non-African populations. In addition, our data point to the neck region as the functional target of such selective pressures: CD209 presents a constant size in the neck region populationwide, whereas CD209L presents an excess of length variation, particularly in non-African populations. An additional interesting observation came from the coalescent-based CD209 gene tree, whose binary topology and time depth (approximately 2.8 million years ago) are compatible with an ancestral population structure in Africa. Altogether, our study has revealed that even a short segment of the human genome can uncover an extraordinarily complex evolutionary history, including different pathogen pressures on host genes as well as traces of admixture among archaic hominid populations.

Photolysis of highly brominated flame retardants leads to time-dependent dioxin-responsive mRNA expression in chicken embryonic hepatocytes.

PubMed

Su, Guanyong; Letcher, Robert J; Farmahin, Reza; Crump, Doug

2018-03-01

Tetradecabromo-1,4-diphenoxybenzene (TeDB-DiPhOBz) and 2,2',3,3',4,4',5,5',6,6'-decabromodiphenyl ether (BDE-209) are flame retardant chemicals that can undergo photolytic degradation. The present study compared the time-dependent photolyic degradation of TeDB-DiPhOBz and BDE-209, and dioxin-like product formation as a result of (UV) irradiation (I; irradiation time periods of 0, 1, 4, 15 and 40 days). Photo-degraded product fractions of UV-I-TeDB-DiPhOBz (nominal concentration: 1.9 μM) were administered to chicken embryonic hepatocytes (CEH), and significant induction of CYP1A4/5 mRNA expression was observed for fractions collected at the day 15 and 40 time points (fold change of 7.3/3.6 and 9.1/4.7, respectively). For the UV-I-BDE-209 fractions (nominal concentration: 10 μM), significant CYP1A4/5 up-regulation occurred at all time points, and the fraction collected on day 1 induced the greatest fold change of 510/86, followed by 410/68 (day 4) and 110/26 (day 15), respectively. For the UV-I-BDE-209 fraction collected at day 40, significant CEH cytotoxicity was observed. As a result, CYP1A4/5 expression was determined at a nominal concentration of 1 μM instead of 10 μM and CYP1A4/5 fold changes of 11/8.2 (day 40) were observed. Fractions eliciting the greatest CYP1A4/5 mRNA upregulation were further screened for transcriptomic effects using a PCR array comprising 27 dioxin-responsive genes. A total of 6 and 16 of the 27 target genes were up or down-regulated following UV-I-TeDB-DiPhOBz and UV-I-BDE-209 exposure, respectively. Overall, and regardless of the formation rate, these results raise concerns regarding the potential formation of dioxin-like compounds from flame retardants in products and materials such as plastics, and in natural sunlight irradiation situations in the environment (e.g. in landfill sites or electronic waste facilities). Copyright © 2017 Elsevier Ltd. All rights reserved.

Potentially Preventable Deaths Among the Five Leading Causes of Death - United States, 2010 and 2014.

PubMed

García, Macarena C; Bastian, Brigham; Rossen, Lauren M; Anderson, Robert; Miniño, Arialdi; Yoon, Paula W; Faul, Mark; Massetti, Greta; Thomas, Cheryll C; Hong, Yuling; Iademarco, Michael F

2016-11-18

Death rates by specific causes vary across the 50 states and the District of Columbia.* Information on differences in rates for the leading causes of death among states might help state health officials determine prevention goals, priorities, and strategies. CDC analyzed National Vital Statistics System data to provide national and state-specific estimates of potentially preventable deaths among the five leading causes of death in 2014 and compared these estimates with estimates previously published for 2010. Compared with 2010, the estimated number of potentially preventable deaths changed (supplemental material at https://stacks.cdc.gov/view/cdc/42472); cancer deaths decreased 25% (from 84,443 to 63,209), stroke deaths decreased 11% (from 16,973 to 15,175), heart disease deaths decreased 4% (from 91,757 to 87,950), chronic lower respiratory disease (CLRD) (e.g., asthma, bronchitis, and emphysema) deaths increased 1% (from 28,831 to 29,232), and deaths from unintentional injuries increased 23% (from 36,836 to 45,331). A better understanding of progress made in reducing potentially preventable deaths in the United States might inform state and regional efforts targeting the prevention of premature deaths from the five leading causes in the United States.

Synthesis, molecular modeling and biological evaluation of PSB as targeted antibiotics.

PubMed

Cheng, Kui; Zheng, Qing-Zhong; Hou, Jin; Zhou, Yang; Liu, Chang-Hong; Zhao, Jing; Zhu, Hai-Liang

2010-04-01

We described here the design, synthesis, molecular modeling, and biological evaluation of a series of peptide and Schiff bases (PSB) small molecules, inhibitors of Escherichia coli beta-Ketoacyl-acyl carrier protein synthase III (ecKAS III). The initial lead compound was reported by us previously, we continued to carry out structure-activity relationship studies and optimize the lead structure to potent inhibitors in this research. The results demonstrated that both N-(2-(3,5-dichloro-2-hydroxybenzylideneamino)propyl)-2-hydroxybenzamide (1f) and 2-hydroxy-N-(2-(2-hydroxy-5-iodobenzylideneamino)propyl)-4-methylbenzamide (3e) posses good ecKAS III inhibitory activity and well binding affinities by bonding Gly152/Gly209 of ecKAS III and fit into the mouth of the substrate tunnel, and can be as potential antibiotics agent, displaying minimal inhibitory concentration values in the range 0.20-3.13microg/mL and 0.39-3.13microg/mL against various bacteria. Copyright 2010 Elsevier Ltd. All rights reserved.

Distribution and accumulation of polybrominated diphenyl ethers (PBDEs) in Hong Kong mangrove sediments.

PubMed

Zhu, Haowen; Wang, Ying; Wang, Xiaowei; Luan, Tiangang; Tam, Nora F Y

2014-01-15

Polybrominated diphenyl ethers (PBDEs) have been used extensively as brominated flame retardants in various polymers, and have become serious environmental contaminants, particularly in coastal sediments. Mangrove wetlands are important coastal ecosystems in tropical and subtropical regions, and mangrove sediments are often the pollutant sinks due to their close proximity with human activities. In Hong Kong, sediment samples collected from five mangrove swamps were found to be contaminated with PBDEs and the eight measured BDE congeners, including BDE-28, -47, -99, -100, -153, -154, -183 and -209 were detected in all mangrove sediments, indicating that these pollutants were widespread in Hong Kong mangrove wetlands. Among the five swamps, relatively high concentrations of PBDEs were recorded in Mai Po mangrove swamp in the northwestern Hong Kong, which is part of the RAMSAR site but is severely influenced by the pollution from the Pearl River Delta. The depth profile of PBDEs in sediment cores collected from Mai Po also showed the inputs of PBDEs in this mangrove swamp increased year by year. In all sediments, the concentrations of BDE-209 were 1-2 orders of magnitude higher than the other congeners in the same sediment. The concentrations of BDE-209 and ∑PBDEs (defined as the sum of seven targeted BDE congeners except BDE-209) ranged from 1.53 to 75.9 ng g(-1) and from 0.57 to 14.4 ng g(-1), respectively. Among the targeted BDE congeners except BDE-209, slightly different composition was recorded among samples collected from different locations, with BDE-153 and -183 being the pre-dominated congeners. In all mangrove swamps, except Tai O in the southwest of Hong Kong, ∑PBDEs concentrations showed a common trend of landward>seaward>mudflat. The concentrations of ∑PBDEs were significantly correlated with total organic matter (TOM) content in sediments but not with the sediment particle sizes in each mangrove swamp. © 2013.

48 CFR 209.570-3 - Procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... prospective contractor meets the definition of “lead system integrator”; (2) Consider all information... workforce or a system engineering and technical assistance contractor; (2) Shall include a plan for phasing...

Method for the preparation of radon-211. [Patent application

DOEpatents

Meyer, G.J.; Lambrecht, R.M.

1980-10-10

A method is claimed for the production of /sup 211/Rn which can be easily isolated from the target and obtained in high yields. It is claimed that the radioisotope /sup 211/Rn can be prepared by the bombardment of /sup 209/Bi with /sup 7/Li particles using the nuclear reaction /sup 209/Bi(/sup 7/Li,5n)/sup 211/Rn. The /sup 211/Rn can be isolated from the target quite easily by degassing at elevated temperatures and the radiochemical purity of the product is better than 98%. It can thus be used as a generator system for /sup 211/At which is of potential interest in biomedical applications. The excitation function for this reaction is about from 40 to 60 MeV and the cross section for /sup 211/Rn production reaches 650 mb at 53 MeV producing a saturation yield of 5.5 ..mu..Ci/nA.

Barriers to implementing the NICE guidelines for early-onset neonatal infection: cross-sectional survey of neonatal blood culture reporting by laboratories in the UK.

PubMed

Paul, S P; Caplan, E M; Morgan, H A; Turner, P C

2018-04-01

The National Institute for Health and Care Excellence published guidelines for managing early-onset neonatal infections in 2012. It recommended provision for reporting blood cultures (BCs) with growth detected or not detected at 36 h. To determine if this was followed, a telephone survey was conducted amongst lead biomedical scientists based at microbiology laboratories (N = 209) in the UK. Overall, 202/209 responded and 139/202 had on-site facilities for BCs. BC results with growth detected or not detected at 36 h were available out-of-hours in 36/139 (26.6%) and 66/139 (47.5%) neonatal units, respectively. Early discontinuation of antibiotics should lead to improved antibiotic stewardship. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

77 FR 20388 - California State Nonroad Engine Pollution Control Standards; Large Spark-Ignition (LSI) Engines...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-04

...: (1) there is inadequate lead time to permit the development of the necessary technology giving... with section 209(e)(1) of the Clean Air Act, California's LSI regulations must not affect new farming... Act if there is inadequate lead-time to permit the development of technology necessary to meet those...

Elastic Scattering of 65 MeV Protons from Several Nuclei between 16O and 209Bi

NASA Astrophysics Data System (ADS)

Ahmed, Syed; Akther, Parvin; Ferdous, Nasima; Begum, Amena; Gupta, Hiranmay

1997-10-01

Elastic scattering of 65 MeV polarized protons from twenty five nuclei ranging from 16O to 209Bi have been analysed within the framework of the nine parameter optical model. A set of optical model parameters has been obtained which shows the systematic behaviour of the target mass dependence of the real potential, volume integral and the r.m.s. radius. The isotopic spin dependence of the real potential has also been studied. Parameters obtained by fitting the elastic scattering data have been able to reproduce the pickup and stripping reaction cross sections as studied in a few cases.

40 CFR 421.104 - Standards of performance for new sources.

Code of Federal Regulations, 2013 CFR

2013-07-01

... pounds) of tungstic acid (as W) produced Lead 11.490 5.333 Zinc 41.850 17.230 Ammonia (as N) 5,469.000 2... Lead 1.003 0.466 Zinc 3.653 1.504 Ammonia (as N) 477.400 209.900 Total suspended solids 53.720 42.970 p... pounds) of sodium tungstate (as W) produced Lead 0.000 0.000 Zinc 0.000 0.000 Ammonia (as N) 0.000 0.000...

40 CFR 421.104 - Standards of performance for new sources.

Code of Federal Regulations, 2014 CFR

2014-07-01

... pounds) of tungstic acid (as W) produced Lead 11.490 5.333 Zinc 41.850 17.230 Ammonia (as N) 5,469.000 2... Lead 1.003 0.466 Zinc 3.653 1.504 Ammonia (as N) 477.400 209.900 Total suspended solids 53.720 42.970 p... pounds) of sodium tungstate (as W) produced Lead 0.000 0.000 Zinc 0.000 0.000 Ammonia (as N) 0.000 0.000...

40 CFR 421.104 - Standards of performance for new sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

... pounds) of tungstic acid (as W) produced Lead 11.490 5.333 Zinc 41.850 17.230 Ammonia (as N) 5,469.000 2... Lead 1.003 0.466 Zinc 3.653 1.504 Ammonia (as N) 477.400 209.900 Total suspended solids 53.720 42.970 p... pounds) of sodium tungstate (as W) produced Lead 0.000 0.000 Zinc 0.000 0.000 Ammonia (as N) 0.000 0.000...

40 CFR 421.104 - Standards of performance for new sources.

Code of Federal Regulations, 2012 CFR

2012-07-01

... pounds) of tungstic acid (as W) produced Lead 11.490 5.333 Zinc 41.850 17.230 Ammonia (as N) 5,469.000 2... Lead 1.003 0.466 Zinc 3.653 1.504 Ammonia (as N) 477.400 209.900 Total suspended solids 53.720 42.970 p... pounds) of sodium tungstate (as W) produced Lead 0.000 0.000 Zinc 0.000 0.000 Ammonia (as N) 0.000 0.000...

48 CFR 252.209-7006 - Limitations on Contractors Acting as Lead System Integrators.

Code of Federal Regulations, 2010 CFR

2010-10-01

... system(s), subsystem(s), system of systems, or services described in this solicitation. (d) If the... through a process over which the offeror exercised no control. (f) This provision implements the...

Identification of H209 as Essential for pH 8-Triggered Receptor-Independent Syncytium Formation by S Protein of Mouse Hepatitis Virus A59.

PubMed

Li, Pei; Shan, Yiwei; Zheng, Wangliang; Ou, Xiuyuan; Mi, Dan; Mu, Zhixia; Holmes, Kathryn V; Qian, Zhaohui

2018-06-01

The spike glycoprotein (S) of murine coronavirus mouse hepatitis virus (MHV) strain A59 uses murine carcinoembryonic antigen-related cell adhesion molecule 1a as its receptor for cell entry, but S protein can also be triggered in the absence of receptor by pH 8.0 alone at 37°C. The mechanism by which conformational changes of this S glycoprotein can be triggered by pH 8.0 has not yet been determined. Here, we show that MHV-A59 S protein is triggered by pH 8.0 at 37°C to induce receptor-independent syncytium (RIS) formation on 293T cells, and that the conformational changes in S proteins triggered by pH 8.0 are very similar to those triggered by receptor binding. We systemically mutated each of 15 histidine residues in S protein and found that H209 is essential for pH 8.0-triggered RIS formation, while H179, H441, H643, and H759 also play important roles in this process. Replacement of H209 with Ala had no effect on receptor binding, but in murine 17Cl.1 cells mutant H209A MHV-A59 showed delayed growth kinetics and was readily outcompeted by wild-type virus when mixed together, indicating that the H209A mutation caused a defect in virus fitness. Finally, the H209A mutation significantly increased the thermostability of S protein in its prefusion conformation, which may raise the energy barrier for conformational change of S protein required for membrane fusion and lead to a decrease in virus fitness in cell culture. Thus, MHV-A59 may have evolved to lower the stability of its S protein in order to increase virus fitness. IMPORTANCE Enveloped viruses enter cells through fusion of viral and cellular membranes, and the process is mediated by interactions between viral envelope proteins and their host receptors. In the prefusion conformation, viral envelope proteins are metastable, and activation to the fusion conformation is tightly regulated, since premature activation would lead to loss of viral infectivity. The stability of viral envelope proteins greatly influences their activation and virus fitness. Here, we report that, similar to the A82V mutation in Ebola glycoprotein, in the S glycoprotein of murine coronavirus MHV-A59, the histidine residue at position of 209 significantly affects the thermal stability of the S protein, determines whether S protein can be activated at 37°C by either pH 8.0 alone or by receptor binding, and affects viral fitness in cell culture. Thus, the spike glycoprotein of MHV-A59 has evolved to retain histidine at position 209 to optimize virus fitness. Copyright © 2018 American Society for Microbiology.

40 CFR 421.106 - Pretreatment standards for new sources.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Lead 11.490 5.333 Zinc 41.850 17.230 Ammonia (as N) 5,469.000 2,404.000 (b) Subpart J—Acid Leach Wet....504 Ammonia (as N) 477.400 209.900 (c) Subpart J—Alkali Leach Wash. PSNS Pollutant or pollutant... (as W) produced Lead 0.000 0.000 Zinc 0.000 0.000 Ammonia (as N) 0.000 0.000 (d) Subpart J—Alkali...

40 CFR 421.106 - Pretreatment standards for new sources.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Lead 11.490 5.333 Zinc 41.850 17.230 Ammonia (as N) 5,469.000 2,404.000 (b) Subpart J—Acid Leach Wet....504 Ammonia (as N) 477.400 209.900 (c) Subpart J—Alkali Leach Wash. PSNS Pollutant or pollutant... (as W) produced Lead 0.000 0.000 Zinc 0.000 0.000 Ammonia (as N) 0.000 0.000 (d) Subpart J—Alkali...

40 CFR 421.106 - Pretreatment standards for new sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Lead 11.490 5.333 Zinc 41.850 17.230 Ammonia (as N) 5,469.000 2,404.000 (b) Subpart J—Acid Leach Wet....504 Ammonia (as N) 477.400 209.900 (c) Subpart J—Alkali Leach Wash. PSNS Pollutant or pollutant... (as W) produced Lead 0.000 0.000 Zinc 0.000 0.000 Ammonia (as N) 0.000 0.000 (d) Subpart J—Alkali...

40 CFR 421.106 - Pretreatment standards for new sources.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Lead 11.490 5.333 Zinc 41.850 17.230 Ammonia (as N) 5,469.000 2,404.000 (b) Subpart J—Acid Leach Wet....504 Ammonia (as N) 477.400 209.900 (c) Subpart J—Alkali Leach Wash. PSNS Pollutant or pollutant... (as W) produced Lead 0.000 0.000 Zinc 0.000 0.000 Ammonia (as N) 0.000 0.000 (d) Subpart J—Alkali...

40 CFR 421.105 - Pretreatment standards for existing sources.

Code of Federal Regulations, 2013 CFR

2013-07-01

... tungstic acid (as W) produced Lead 11.490 5.333 Zinc 41.850 17.230 Ammonia (as N) 5,469.000 2,404.000 (b... 0.466 Zinc 3.653 1.504 Ammonia (as N) 477.400 209.900 (c) Subpart J—Alkali Leach Wash. PSES... pounds) of tungstate (as W) produced Lead 0.000 0.000 Zinc 0.000 0.000 Ammonia (as N) 0.000 0.000 (d...

40 CFR 421.105 - Pretreatment standards for existing sources.

Code of Federal Regulations, 2014 CFR

2014-07-01

... tungstic acid (as W) produced Lead 11.490 5.333 Zinc 41.850 17.230 Ammonia (as N) 5,469.000 2,404.000 (b... 0.466 Zinc 3.653 1.504 Ammonia (as N) 477.400 209.900 (c) Subpart J—Alkali Leach Wash. PSES... pounds) of tungstate (as W) produced Lead 0.000 0.000 Zinc 0.000 0.000 Ammonia (as N) 0.000 0.000 (d...

40 CFR 421.105 - Pretreatment standards for existing sources.

Code of Federal Regulations, 2010 CFR

2010-07-01

... tungstic acid (as W) produced Lead 11.490 5.333 Zinc 41.850 17.230 Ammonia (as N) 5,469.000 2,404.000 (b... 0.466 Zinc 3.653 1.504 Ammonia (as N) 477.400 209.900 (c) Subpart J—Alkali Leach Wash. PSES... pounds) of tungstate (as W) produced Lead 0.000 0.000 Zinc 0.000 0.000 Ammonia (as N) 0.000 0.000 (d...

40 CFR 421.105 - Pretreatment standards for existing sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

... tungstic acid (as W) produced Lead 11.490 5.333 Zinc 41.850 17.230 Ammonia (as N) 5,469.000 2,404.000 (b... 0.466 Zinc 3.653 1.504 Ammonia (as N) 477.400 209.900 (c) Subpart J—Alkali Leach Wash. PSES... pounds) of tungstate (as W) produced Lead 0.000 0.000 Zinc 0.000 0.000 Ammonia (as N) 0.000 0.000 (d...

40 CFR 421.105 - Pretreatment standards for existing sources.

Code of Federal Regulations, 2012 CFR

2012-07-01

... tungstic acid (as W) produced Lead 11.490 5.333 Zinc 41.850 17.230 Ammonia (as N) 5,469.000 2,404.000 (b... 0.466 Zinc 3.653 1.504 Ammonia (as N) 477.400 209.900 (c) Subpart J—Alkali Leach Wash. PSES... pounds) of tungstate (as W) produced Lead 0.000 0.000 Zinc 0.000 0.000 Ammonia (as N) 0.000 0.000 (d...

40 CFR 421.106 - Pretreatment standards for new sources.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Lead 11.490 5.333 Zinc 41.850 17.230 Ammonia (as N) 5,469.000 2,404.000 (b) Subpart J—Acid Leach Wet....504 Ammonia (as N) 477.400 209.900 (c) Subpart J—Alkali Leach Wash. PSNS Pollutant or pollutant... (as W) produced Lead 0.000 0.000 Zinc 0.000 0.000 Ammonia (as N) 0.000 0.000 (d) Subpart J—Alkali...

Measurement and Analysis of Neutron Leakage Spectra from Pb and LBE Cylinders with D-T Neutrons

NASA Astrophysics Data System (ADS)

Chen, Size; Gan, Leting; Li, Taosheng; Han, Yuncheng; Liu, Chao; Jiang, Jieqiong; Wu, Yican

2017-09-01

For validating the current evaluated neutron data libraries, neutron leakage spectra from lead and lead bismuth eutectic (LBE) cylinders have been measured using an intense D-T pulsed neutron source with time-of-flight (TOF) method by Institute of Nuclear Energy Safety Technology (INEST), Chinese Academy of Sciences (CAS). The measured leakage spectra have been compared with the calculated ones using Super Monte Carlo Simulation Program for Nuclear and Radiation Process (SuperMC) with the evaluated pointwise data of lead and bismuth processed from ENDF/B-VII.1, JEFF-3.1 and JENDL-4.0 libraries. This work shows that calculations of the three libraries are all generally consistent with the lead experimental result. For LBE experiment, the JEFF-3.1 and JENDL-4.0 calculations both agree well with the measurement. However, the result of ENDF/B-VII.1 fails to fit with the measured data, especially in the energy range of 5.5 and 7 MeV with difference more than 80%. Through sensitivity analysis with partial cross sections of 209Bi in ENDF/B-VII.1 and JEFF, the difference between the measurement and the ENDF/B-VII.1 calculation in LBE experiment is found due to the neutron data of 209Bi.

Measurements of cross sections for the 209Bi(n, 4n) reaction by using high energy neutrons with continuous energy spectra

NASA Astrophysics Data System (ADS)

Min, Kyung Joo; Bak, Sang-In; Ham, Cheolmin; In, Eun Jin; Kim, Do Yoon; Myung, Hyunjeong; Shim, Chungbo; Shin, Jae Won; Zhou, Yujie; Park, Tae-Sun; Hong, Seung-Woo; Bhoraskar, V. N.

2017-09-01

We measured 209Bi(n, 4n) cross sections at neutron energies En = 29.8 ± 1.8 MeV and En = 34.8 ± 1.8 MeV. Bismuth oxide samples were irradiated with the neutrons produced by impinging 30, 35 and 40 MeV proton beams on a 1.05 cm thick beryllium target, where the proton beams were from the MC-50 Cyclotron of Korea Institute of Radiological Medical Sciences (KIRAMS). The neutron flux for each proton beam energy Ep, ΦEp(En), has a broad spectrum with respect to En. By taking the difference in the neutron fluxes, the difference spectra, Φ40(En) -Φ35(En) and Φ35(En) -Φ30(En), are obatined and found to be peaked at En = 29.8 and 34.8 MeV, respectively, with a width of about 3.6 MeV. By making use of this observation and employing the TENDL-2009 library we could extract the 209Bi(n, 4n)206Bi cross sections at the aforementioned neutron energies.

A study of oxidative stress induced by two polybrominated diphenyl ethers in the rotifer Brachionus plicatilis.

PubMed

Zhang, Jing; Wang, You; Sun, Kai-Ming; Fang, Kuan; Tang, Xuexi

2016-12-15

Polybrominated diphenyl ethers (PBDEs) are widely dispersed persistent organic pollutants in the marine ecosystem. However, their toxic mechanisms in marine organisms, especially invertebrates, remain poorly understood. Two common congeners of PBDEs, tetrabrominated diphenyl ether-47 (BDE-47) and decabrominated diphenyl ether-209 (BDE-209), were investigated. Their toxic mechanisms, with a focus on oxidative stress, were examined in rotifer Brachionus plicatilis. Overproduction of reactive oxygen species (ROS) was induced by two PBDEs. The expression of superoxide dismutase (SOD) mRNA was increased, suggesting SOD play a main role in ROS-scavenging. The intercellular concentrations of calcium ([Ca 2+ ] in ) and the expression of calmodulin (CaM) mRNA were increased. This indicates the calcium ion (Ca 2+ ) signaling channel is involved in PBDEs stress. Further analysis showed that the reproductive system might be the target site for toxicity of PBDEs. Moreover, high value of detection indexes in BDE-47 experimental groups suggested BDE-47 might cause higher oxidative damage than BDE-209 in rotifers. Copyright © 2016 Elsevier Ltd. All rights reserved.

Polybrominated diphenyl ether (PBDE) levels in dust from previously owned automobiles at United States dealerships.

PubMed

Lagalante, Anthony F; Oswald, Timothy D; Calvosa, Frank C

2009-04-01

The levels of BDE-28, BDE-47, BDE-99, BDE-100, BDE-153, BDE-154, BDE-183, and BDE-209 were determined in the dust sampled from 60 automobiles that were available for resale at U.S. dealerships. The dominant congener in automobile dust was BDE-209 comprising 95% of the total PBDE levels with a median level of 48.1 microg g(-1). Statistical analysis of the vehicle attributes indicates that the BDE-209 levels are different (p<0.05) with respect to groupings by vehicle model year, vehicle manufacturer, and the country of manufacture. Vehicle dust samples contained the characteristic profile of the PBDE congeners that comprise the PentaBDE formulation. While DecaBDE use is banned in Maine and Washington and is targeted for restriction in the near future by six U.S. states, vehicles and airplanes are exempt from the ban. It is anticipated that the human exposure potential to PBDEs from automobile dust ingestion will continue for an indefinite future period in the U.S. population.

49 CFR 209.209 - Hearing.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Hearing. 209.209 Section 209.209 Transportation... TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Compliance Orders § 209.209 Hearing. (a) When a respondent... and the respondent fail to agree upon an acceptable consent order, the hearing officer designated by...

49 CFR 209.209 - Hearing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Hearing. 209.209 Section 209.209 Transportation... TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Compliance Orders § 209.209 Hearing. (a) When a respondent... and the respondent fail to agree upon an acceptable consent order, the hearing officer designated by...

48 CFR 3009.570-1 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SECURITY ACQUISITION REGULATION (HSAR) ACQUISITION PLANNING CONTRACTOR QUALIFICATIONS Organizational and Consultant Conflicts of Interest 3009.570-1 Definitions. “Direct Financial Interest,” as used in this section, is defined in the clause at HSAR 48 CFR 3052.209-75, Prohibited Financial Interests for Lead System...

Does Compound Nucleus remember its Isospin- An Evidence from the Fission Widths

NASA Astrophysics Data System (ADS)

Garg, Swati; Jain, Ashok Kumar

2018-05-01

We present an evidence of isospin effects in nuclear fission by comparing the fission widths for reactions involving different isospin states of the same compound nucleus (CN). Yadrovsky [1] suggested this possibility in 1975. Yadrovsky obtained the fission widths for two reaction data sets, namely 206Pb(α,f) and 209Bi(p,f), both leading to same CN, and concluded that "a nucleus remembers the isospin value of the nuclear states leading to fission". We obtain the fission decay widths for both the T0 + ½ and T0 - ½ states of CN by using two appropriate reaction data sets. We then compare the fission widths for the two isospin states of CN. More specifically, we have chosen the combination of 206Pb(α,f) and 209Bi(p,f) same as presented in Yadrovsky's paper [1] in this study. A significant difference between the ratios of fission decay widths to total decay widths for different isospin values suggests that isospin plays an important role in fission.

Uveal Melanoma: Identifying Immunological and Chemotherapeutic Targets to Treat Metastases.

PubMed

Jager, Martine J; Dogrusöz, Mehmet; Woodman, Scott E

2017-01-01

Uveal melanoma is an intraocular malignancy that, depending on its size and genetic make-up, may lead to metastases in up to 50% of cases. Currently, no therapy has been proven to improve survival. However, new therapies exploiting immune responses against metastases are being developed. The primary tumor is well characterized: tumors at high risk of developing metastases often contain macrophages and lymphocytes. However, these lymphocytes are often regulatory T cells that may suppress immune response. Currently, immune checkpoint inhibitors have shown marked efficacy in multiple cancers (eg, cutaneous melanoma) but do not yet improve survival in uveal melanoma patients. More knowledge needs to be acquired regarding the function of T cells in uveal melanoma. Other therapeutic options are related to the biochemical pathways. Targeting the RAF-MEK-ERK pathway with small molecule MEK inhibitors abrogates the growth of UM cells harboring GNAQ/GNA11 Q209 mutations, suggesting that these aberrant G-protein oncogenes mediate, at least in part, their effect through this hallmark proliferation pathway. Other pathways are also implicated, such as those involving c-Jun and YAP. Further studies may show how interference in the different pathways may affect survival. Copyright 2017 Asia-Pacific Academy of Ophthalmology.

Phosphorylation of Arabidopsis ubiquitin ligase ATL31 is critical for plant carbon/nitrogen nutrient balance response and controls the stability of 14-3-3 proteins.

PubMed

Yasuda, Shigetaka; Sato, Takeo; Maekawa, Shugo; Aoyama, Shoki; Fukao, Yoichiro; Yamaguchi, Junji

2014-05-30

Ubiquitin ligase plays a fundamental role in regulating multiple cellular events in eukaryotes by fine-tuning the stability and activity of specific target proteins. We have previously shown that ubiquitin ligase ATL31 regulates plant growth in response to nutrient balance between carbon and nitrogen (C/N) in Arabidopsis. Subsequent study demonstrated that ATL31 targets 14-3-3 proteins for ubiquitination and modulates the protein abundance in response to C/N-nutrient status. However, the underlying mechanism for the targeting of ATL31 to 14-3-3 proteins remains unclear. Here, we show that ATL31 interacts with 14-3-3 proteins in a phosphorylation-dependent manner. We identified Thr(209), Ser(247), Ser(270), and Ser(303) as putative 14-3-3 binding sites on ATL31 by motif analysis. Mutation of these Ser/Thr residues to Ala in ATL31 inhibited the interaction with 14-3-3 proteins, as demonstrated by yeast two-hybrid and co-immunoprecipitation analyses. Additionally, we identified in vivo phosphorylation of Thr(209) and Ser(247) on ATL31 by MS analysis. A peptide competition assay showed that the application of synthetic phospho-Thr(209) peptide, but not the corresponding unphosphorylated peptide, suppresses the interaction between ATL31 and 14-3-3 proteins. Moreover, Arabidopsis plants overexpressing mutated ATL31, which could not bind to 14-3-3 proteins, showed accumulation of 14-3-3 proteins and growth arrest in disrupted C/N-nutrient conditions similar to wild-type plants, although overexpression of intact ATL31 resulted in repression of 14-3-3 accumulation and tolerance to the conditions. Together, these results demonstrate that the physiological role of phosphorylation at 14-3-3 binding sites on ATL31 is to modulate the binding ability and stability of 14-3-3 proteins to control plant C/N-nutrient response. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

GNQ-209P Mutation in Metastatic Uveal Melanoma and Treatment Outcome.

PubMed

Abdel Karim, Nagla; Eldessouki, Ihab; Taftaf, Ahmad; Ayham, Deeb; Gaber, Ola; Makramalla, Abouelmagd; Correa, Zelia M

2018-01-01

Metastatic prognosis in uveal melanoma is assessed by gene expression profiling (GEP) testing of the tumor cells, usually obtained by fine needle aspiration (FNA). GEP has demonstrated high accuracy in distinguishing class I and II tumors, both having different metastatic potential. Transcriptomic studies identified distinct mutations including somatic mutations in GNAQ and GNA11 , detected in more than 80%, and contribute to the upregulation of the mitogen-activated protein kinase (MAPK) pathway and the development of uveal melanoma (UM). The role of these mutations in treatment selection and possible benefit from targeted therapy are somewhat unclear. However, until the discovery of novel agents, local versus systemic therapies remain options for treatment that can still be considered for disease control in certain cases. We report a series of patients with metastatic UM with distinct mutational profiles. One had significant liver metastases with proven GNQ-209P mutation on tissue biopsy while peripheral blood molecular profiling did not show these mutations. The other three cases had no GNQ-209P mutation. All cases received nab-paclitaxel (Abraxane) as a treatment drug, and we record their responses to treatment and their molecular-profiling results.

49 CFR 209.101 - Civil penalties generally.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Civil penalties generally. 209.101 Section 209.101..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Hazardous Materials Penalties Civil Penalties § 209.101 Civil penalties generally. (a) Sections 209.101 through 209.121 prescribe rules of...

49 CFR 209.101 - Civil penalties generally.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Civil penalties generally. 209.101 Section 209.101..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Hazardous Materials Penalties Civil Penalties § 209.101 Civil penalties generally. (a) Sections 209.101 through 209.121 prescribe rules of...

The Environmentally Sound Aquaculture Strategies Based on Bioaccumulation of Heavy Metal of Lead (Pb) on Seaweed of Gracilaria verrucosa on Aquaculture Areas of MuararejaVillage, Tegal City

NASA Astrophysics Data System (ADS)

Nurjanah; Ambariyanto; Supriharyono; Yulianto, Bambang

2018-02-01

Community activities such as industry, trade, animal husbandry and agriculture and ssettlements resulting in heavy metals of lead (Pb) can be accumulated in water, sediment and seaweed Gracillaria verrucosa. It can contaminate ponds and affect aquaculture activities in Tegal. Seaweed Gracilaria verrucosa is afisheries commodity that has economical value and cultivated in the area of aquaculture MuararejaTegal. It can serve as fitoremedian that will help reduce the impact of heavy metal pollution due to its ability to accumulate pollutants. The objective of this study was to analyze bioaccumulation of heavy metals of lead (Pb) and its relationship with water quality management in order to develop seaweed cultivation of Gracillaria verrucosa in ponds in the area of aquaculture MuararejaTegal. The method used in this study is a survey, analysis of heavy metals of lead (Pb) in pond water, sediment and seaweed using Atomic Absorption Spectrophotometer (AAS) and the data were analyzed by descriptive quantitative. Bioconcentration of lead (Pb) during the dry season in pond water, sediment and seaweed Gracillaria verrucosa was measured from 0.003 to 0.025 ppm,5.543 to 23.699 ppm and 0.209 to 0.326 ppm respectively. While in the rainy season bioconcentration of lead (Pb) are from 0.003 to 0.015 ppm, sediment from 6.377 to 9.858 ppm and 0.209 to 0.326 ppm respectively. Bioconcentration of Pb in dry season was higher than in the rainy season and the biggest bioconcentration was found in the sediment pond waters. Pb bioaccumulation low and still below the quality standards of the Ministry of Environment decision 51 of 2004 so that the product is safe for consumption.

Cross sections of proton-induced nuclear reactions on bismuth and lead up to 100 MeV

NASA Astrophysics Data System (ADS)

Mokhtari Oranj, L.; Jung, N. S.; Bakhtiari, M.; Lee, A.; Lee, H. S.

2017-04-01

Production cross sections of 209Bi(p , x n )207,206,205,204,203Po, 209Bi(p , pxn) 207,206,205,204,203,202Bi, and natPb(p , x n ) 206,205,204,203,202,201Bi reactions were measured to fill the gap in the excitation functions up to 100 MeV as well as to figure out the effects of different nuclear properties on proton-induced reactions including heavy nuclei. The targets were arranged in two different stacks consisting of Bi, Pb, Al, Au foils and Pb plates. The proton beam intensity was determined by the activation analysis method using 27Al(p ,3 p n )24Na, 197Au(p ,p n )196Au, and 197Au(p , p 3 n )194Au monitor reactions in parallel as well as the Gafchromic film dosimetry method. The activities of produced radionuclei in the foils were measured by the HPGe spectroscopy system. Over 40 new cross sections were measured in the investigated energy range. A satisfactory agreement was observed between the present experimental data and the previously published data. Excitation functions of mentioned reactions were calculated by using the theoretical model based on the latest version of the TALYS code and compared to the new data as well as with other data in the literature. Additionally, the effects of various combinations of the nuclear input parameters of different level density models, optical model potentials, and γ-ray strength functions were considered. It was concluded that if certain level density models are used, the calculated cross sections could be comparable to the measured data. Furthermore, the effects of optical model potential and γ-ray strength functions were considerably lower than that of nuclear level densities.

48 CFR 3052.209-75 - Prohibited financial interests for lead system integrators.

Code of Federal Regulations, 2010 CFR

2010-10-01

... for the development or production of a major system, if the prime contractor is not expected at the time of award to perform a substantial portion of the work on the system and the major subsystems. (4... procurement of services, the primary purpose of which is to perform acquisition functions closely associated...

48 CFR 252.209-7007 - Prohibited Financial Interests for Lead System Integrators.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contractor for the development or production of a major system, if the prime contractor is not expected at the time of award to perform a substantial portion of the work on the system and the major subsystems... for the procurement of services, the primary purpose of which is to perform acquisition functions...

A novel fluorescent aptasensor based on hairpin structure of complementary strand of aptamer and nanoparticles as a signal amplification approach for ultrasensitive detection of cocaine.

PubMed

Emrani, Ahmad Sarreshtehdar; Danesh, Noor Mohammad; Ramezani, Mohammad; Taghdisi, Seyed Mohammad; Abnous, Khalil

2016-05-15

Cocaine is one of the most commonly misused stimulant which could influence the central nervous system. In this study, a fluorescent aptamer-based sensor (aptasensor) was designed for sensitive and selective detection of cocaine, based on hairpin structure of complementary strand of aptamer (CS), target-induced release of aptamer (Apt) from CS and two kinds of nanoparticles, including silica nanoparticles (SNPs) coated with streptavidin and gold nanoparticles (AuNPs). The designed aptasensor acquires characteristics of AuNPs such as unique optical properties and large surface area, SNPs as amplifiers of fluorescence intensity, higher affinity of Apt toward its target relative to its CS, and finally the hairpin structure of CS that brings the fluorophore (FAM) to close proximity to the surface of SNPs. In the absence of cocaine, FAM is in close proximity to the surface of AuNPs, resulting in a weak fluorescence emission. In the presence of target, FAM comes to close proximity to the surface of SNPs because of the formation of hairpin structure of CS, leading to a very strong fluorescence emission. The fabricated fluorescent aptasensor exhibited a good selectivity toward cocaine with a limit of detection (LOD) as low as 209 pM. Moreover, the designed aptasensor was successfully utilized to detect cocaine in serum with a LOD as low as 293 pM. Copyright © 2015 Elsevier B.V. All rights reserved.

49 CFR 209.321 - Hearing.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Hearing. 209.321 Section 209.321 Transportation... TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Disqualification Procedures § 209.321 Hearing. (a) Upon receipt of a hearing request complying with § 209.311, an administrative hearing for review of a notice of...

49 CFR 209.321 - Hearing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Hearing. 209.321 Section 209.321 Transportation... TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Disqualification Procedures § 209.321 Hearing. (a) Upon receipt of a hearing request complying with § 209.311, an administrative hearing for review of a notice of...

Photofission of 197Au and 209Bi at intermediate energies

NASA Astrophysics Data System (ADS)

Haba, H.; Sakamoto, K.; Igarashi, M.; Kasaoka, M.; Washiyama, K.; Matsumura, H.; Oura, Y.; Shibata, S.; Furukawa, M.; Fujiwara, I.

2003-01-01

Recoil properties and yields of radionuclides formed in the photofission of 197Au and 209Bi by bremsstrahlung of end-point energies ( E 0) from 300 to 1100 MeV have been investigated using the thick-target thick-catcher method. The kinetic energies T of the residual nuclei were deduced based on the two-step vector model and discussed by comparing with the reported results on protoninduced reactions as well as those on photospallation. The charge distribution was reproduced by a Gaussian function with the most probable charge Zp expressed by a linera function of the product mass number A and with the A-independent width FWHM CD. Based on the charge distribution parameters, the symmetric mass yield distribution with the most probable mass A p of 92 m.u. and the width FWHM MD of 39 m.u. was obtained for 197Au at E 0≥600 MeV. The A p value for 209Bi was larger by 4 m.u. than that for 197Au and the FWHM MD was smaller by 6 m.u. A comparison with the calculations using the Photon-induced Intranuclear Cascade Analysis 3 code combined with the Generalized Evaporation Model code (PICA3/GEM) was also performed.

22 CFR 209.9 - Hearings.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Hearings. 209.9 Section 209.9 Foreign Relations... INTERNATIONAL DEVELOPMENT-EFFECTUATION OF TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 § 209.9 Hearings. (a) Opportunity for hearing. Whenever an opportunity for a hearing is required by § 209.8(c), reasonable notice...

22 CFR 209.9 - Hearings.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Hearings. 209.9 Section 209.9 Foreign Relations... INTERNATIONAL DEVELOPMENT-EFFECTUATION OF TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 § 209.9 Hearings. (a) Opportunity for hearing. Whenever an opportunity for a hearing is required by § 209.8(c), reasonable notice...

22 CFR 209.9 - Hearings.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Hearings. 209.9 Section 209.9 Foreign Relations... INTERNATIONAL DEVELOPMENT-EFFECTUATION OF TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 § 209.9 Hearings. (a) Opportunity for hearing. Whenever an opportunity for a hearing is required by § 209.8(c), reasonable notice...

22 CFR 209.9 - Hearings.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Hearings. 209.9 Section 209.9 Foreign Relations... INTERNATIONAL DEVELOPMENT-EFFECTUATION OF TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 § 209.9 Hearings. (a) Opportunity for hearing. Whenever an opportunity for a hearing is required by § 209.8(c), reasonable notice...

49 CFR 350.211 - What is the format of the certification required by § 350.209?

Code of Federal Regulations, 2011 CFR

2011-10-01

... FMCSRs and the HMRs. 2. The State has designated (name of State CMV safety agency) as the lead agency to... inspected CMVs. 5. The State requires that all reports relating to the program be submitted to the... requirement that registrants of CMVs declare their knowledge of the applicable Federal or State CMV safety...

49 CFR 350.211 - What is the format of the certification required by § 350.209?

Code of Federal Regulations, 2013 CFR

2013-10-01

... FMCSRs and the HMRs. 2. The State has designated (name of State CMV safety agency) as the lead agency to... inspected CMVs. 5. The State requires that all reports relating to the program be submitted to the... requirement that registrants of CMVs declare their knowledge of the applicable Federal or State CMV safety...

49 CFR 350.211 - What is the format of the certification required by § 350.209?

Code of Federal Regulations, 2014 CFR

2014-10-01

... FMCSRs and the HMRs. 2. The State has designated (name of State CMV safety agency) as the lead agency to... inspected CMVs. 5. The State requires that all reports relating to the program be submitted to the... requirement that registrants of CMVs declare their knowledge of the applicable Federal or State CMV safety...

49 CFR 350.211 - What is the format of the certification required by § 350.209?

Code of Federal Regulations, 2010 CFR

2010-10-01

... FMCSRs and the HMRs. 2. The State has designated (name of State CMV safety agency) as the lead agency to... inspected CMVs. 5. The State requires that all reports relating to the program be submitted to the... requirement that registrants of CMVs declare their knowledge of the applicable Federal or State CMV safety...

49 CFR 350.211 - What is the format of the certification required by § 350.209?

Code of Federal Regulations, 2012 CFR

2012-10-01

... FMCSRs and the HMRs. 2. The State has designated (name of State CMV safety agency) as the lead agency to... inspected CMVs. 5. The State requires that all reports relating to the program be submitted to the... requirement that registrants of CMVs declare their knowledge of the applicable Federal or State CMV safety...

[Benchmarking in ambulatory care practices--The European Practice Assessment (EPA)].

PubMed

Szecsenyi, Joachim; Broge, Björn; Willms, Sara; Brodowski, Marc; Götz, Katja

2011-01-01

The European Practice Assessment (EPA) is a comprehensive quality management which consists of 220 indicators covering 5 domains (infrastructure, people, information, finance, and quality and safety). The aim of the project presented was to evaluate EPA as an instrument for benchmarking in ambulatory care practices. A before-and-after design with a comparison group was chosen. One hundred and two practices conducted EPA at baseline (t1) and at the 3-year follow-up (t2). A further 209 practices began EPA at t2 (comparison group). Since both practice groups differed in several variables (age of GP, location and size of practice), a matched-pair design based on propensity scores was applied leading to a subgroup of 102 comparable practices (out of the 209 practices). Data analysis was carried out using Z scores of the EPA domains. The results showed significant improvements in all domains between t1 and t2 as well as between the comparison group and t2. Furthermore, the results demonstrate that the implementation of total quality management and the re-assessment of the EPA procedure can lead to significant improvements in almost all domains. Copyright © 2011. Published by Elsevier GmbH.

The MNK–eIF4E Signaling Axis Contributes to Injury-Induced Nociceptive Plasticity and the Development of Chronic Pain

PubMed Central

Asiedu, Marina N.; Megat, Salim; Burton, Michael D.; Burgos-Vega, Carolina C.; Melemedjian, Ohannes K.; Boitano, Scott; Vagner, Josef; Pancrazio, Joseph J.; Mogil, Jeffrey S.; Dussor, Gregory

2017-01-01

Injury-induced sensitization of nociceptors contributes to pain states and the development of chronic pain. Inhibiting activity-dependent mRNA translation through mechanistic target of rapamycin and mitogen-activated protein kinase (MAPK) pathways blocks the development of nociceptor sensitization. These pathways convergently signal to the eukaryotic translation initiation factor (eIF) 4F complex to regulate the sensitization of nociceptors, but the details of this process are ill defined. Here we investigated the hypothesis that phosphorylation of the 5′ cap-binding protein eIF4E by its specific kinase MAPK interacting kinases (MNKs) 1/2 is a key factor in nociceptor sensitization and the development of chronic pain. Phosphorylation of ser209 on eIF4E regulates the translation of a subset of mRNAs. We show that pronociceptive and inflammatory factors, such as nerve growth factor (NGF), interleukin-6 (IL-6), and carrageenan, produce decreased mechanical and thermal hypersensitivity, decreased affective pain behaviors, and strongly reduced hyperalgesic priming in mice lacking eIF4E phosphorylation (eIF4ES209A). Tests were done in both sexes, and no sex differences were found. Moreover, in patch-clamp electrophysiology and Ca2+ imaging experiments on dorsal root ganglion neurons, NGF- and IL-6-induced increases in excitability were attenuated in neurons from eIF4ES209A mice. These effects were recapitulated in Mnk1/2−/− mice and with the MNK1/2 inhibitor cercosporamide. We also find that cold hypersensitivity induced by peripheral nerve injury is reduced in eIF4ES209A and Mnk1/2−/− mice and following cercosporamide treatment. Our findings demonstrate that the MNK1/2–eIF4E signaling axis is an important contributing factor to mechanisms of nociceptor plasticity and the development of chronic pain. SIGNIFICANCE STATEMENT Chronic pain is a debilitating disease affecting approximately one in three Americans. Chronic pain is thought to be driven by changes in the excitability of peripheral nociceptive neurons, but the precise mechanisms controlling these changes are not elucidated. Emerging evidence demonstrates that mRNA translation regulation pathways are key factors in changes in nociceptor excitability. Our work demonstrates that a single phosphorylation site on the 5′ cap-binding protein eIF4E is a critical mechanism for changes in nociceptor excitability that drive the development of chronic pain. We reveal a new mechanistic target for the development of a chronic pain state and propose that targeting the upstream kinase, MAPK interacting kinase 1/2, could be used as a therapeutic approach for chronic pain. PMID:28674170

49 CFR 209.303 - Coverage.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Coverage. 209.303 Section 209.303 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Disqualification Procedures § 209.303 Coverage. This...

49 CFR 209.303 - Coverage.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Coverage. 209.303 Section 209.303 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Disqualification Procedures § 209.303 Coverage. This...

49 CFR 209.303 - Coverage.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Coverage. 209.303 Section 209.303 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Disqualification Procedures § 209.303 Coverage. This...

49 CFR 209.303 - Coverage.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Coverage. 209.303 Section 209.303 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Disqualification Procedures § 209.303 Coverage. This...

49 CFR 209.303 - Coverage.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Coverage. 209.303 Section 209.303 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Disqualification Procedures § 209.303 Coverage. This...

48 CFR 53.209 - Contractor qualifications.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Contractor qualifications. 53.209 Section 53.209 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.209 Contractor qualifications. ...

48 CFR 1553.209 - Contractor qualifications.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contractor qualifications. 1553.209 Section 1553.209 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY CLAUSES AND FORMS FORMS Prescription of Forms 1553.209 Contractor qualifications. ...

Uptake of polybrominated diphenyl ethers by carrot and lettuce crops grown in compost-amended soils.

PubMed

Bizkarguenaga, E; Iparraguirre, A; Oliva, E; Quintana, J B; Rodil, R; Fernández, L A; Zuloaga, O; Prieto, A

2016-02-01

The uptake of polybrominated diphenyl ethers (PBDEs) by carrot and lettuce was investigated. Degradation of PBDEs in soil in the absence of the plants was discarded. Different carrot (Nantesa and Chantenay) and lettuce (Batavia Golden Spring and Summer Queen) varieties were grown in fortified or contaminated compost-amended soil mixtures under greenhouse conditions. After plant harvesting, roots (core and peel) and leaves were analyzed separately for carrot, while for lettuce, leaves and hearts were analyzed together. The corresponding bioconcentration factors (BCFs) were calculated. In carrots, a concentration gradient of 2,2',3,4,4',5'-hexabromodiphenyl ether (BDE-138) became evident that decreased from the root peel via root core to the leaves. For decabromodiphenyl ether (BDE-209) at the low concentration level (7 and 20 ng g(-1)), the leaves incorporated the highest concentration of the target substance. For lettuce, a decrease in the BCF value (from 0.24 to 0.02) was observed the higher the octanol-water partition coefficient, except in the case of BDE-183 (BCF = 0.51) and BDE-209 (BCF values from 0.41 to 0.74). Significant influence of the soils and crop varieties on the uptake could not be supported. Metabolic debromination, hydroxylation or methylation of the target PBDEs in the soil-plant system was not observed.

49 CFR 209.215 - Time limitation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Time limitation. 209.215 Section 209.215 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Compliance Orders § 209.215 Time...

49 CFR 209.215 - Time limitation.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Time limitation. 209.215 Section 209.215 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Compliance Orders § 209.215 Time...

49 CFR 209.215 - Time limitation.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Time limitation. 209.215 Section 209.215 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Compliance Orders § 209.215 Time...

Ultrasound, histopathological, and genetic features of uveal melanoma in a Mexican-Mestizo population.

PubMed

Delgado, S; Rodriguez Reyes, A; Mora Rios, L; Dueñas-González, A; Taja-Chayeb, L; Moragrega Adame, E

2018-01-01

To describe the ultrasound, histopathological and genetic characteristics of uveal melanoma in a Mexican-Mestizo population. A total of 39 enucleated eyes with a histopathological diagnosis of uveal melanoma were assessed by describing the clinical findings, and ultrasound, histopathological and genetic features. A high correlation was observed between tumour height measurement using ultrasound and histopathology. In our cases, tumour size and reflectivity were higher compared with those reported in the literature. The preliminary data on the molecular assessment of the tumours show the presence of an unreported polymorphism (T>C IVS5+34) and one sample with GNAQ mutation (A>C CAA>CCA Gln 209 Pro). Ultrasound is a reliable method to identify the size of the tumour. Furthermore, knowledge of the molecular mechanisms promises new perspectives for the development of new targeted therapeutics. Fortunately this leads to progress in the treatment of patients with metastatic disease or prevents it in those at high risk. Copyright © 2017 Sociedad Española de Oftalmología. Publicado por Elsevier España, S.L.U. All rights reserved.

48 CFR 209.270 - Aviation and ship critical safety items.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Aviation and ship critical safety items. 209.270 Section 209.270 Federal Acquisition Regulations System DEFENSE ACQUISITION... Requirements 209.270 Aviation and ship critical safety items. ...

48 CFR 209.270 - Aviation and ship critical safety items.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Aviation and ship critical safety items. 209.270 Section 209.270 Federal Acquisition Regulations System DEFENSE ACQUISITION... Requirements 209.270 Aviation and ship critical safety items. ...

48 CFR 209.270 - Aviation and ship critical safety items.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Aviation and ship critical safety items. 209.270 Section 209.270 Federal Acquisition Regulations System DEFENSE ACQUISITION... Requirements 209.270 Aviation and ship critical safety items. ...

48 CFR 209.270 - Aviation and ship critical safety items.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Aviation and ship critical safety items. 209.270 Section 209.270 Federal Acquisition Regulations System DEFENSE ACQUISITION... Requirements 209.270 Aviation and ship critical safety items. ...

40 CFR 240.209 - Safety.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Safety. 240.209 Section 240.209 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.209 Safety. ...

48 CFR 209.270 - Aviation and ship critical safety items.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Requirements 209.270 Aviation and ship critical safety items. ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Aviation and ship critical safety items. 209.270 Section 209.270 Federal Acquisition Regulations System DEFENSE ACQUISITION...

49 CFR 209.337 - Information collection.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Information collection. 209.337 Section 209.337 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Information collection. The information collection requirements in § 209.331 of this part have been reviewed...

48 CFR 1436.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2012 CFR

2012-10-01

... with architect-engineer firms. 1436.209 Section 1436.209 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 1436.209 Construction contracts with architect-engineer...

48 CFR 436.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2013 CFR

2013-10-01

... with architect-engineer firms. 436.209 Section 436.209 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 436.209 Construction contracts with architect-engineer...

48 CFR 1436.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... with architect-engineer firms. 1436.209 Section 1436.209 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 1436.209 Construction contracts with architect-engineer...

48 CFR 1436.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... with architect-engineer firms. 1436.209 Section 1436.209 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 1436.209 Construction contracts with architect-engineer...

48 CFR 436.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2014 CFR

2014-10-01

... with architect-engineer firms. 436.209 Section 436.209 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 436.209 Construction contracts with architect-engineer...

48 CFR 2936.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2014 CFR

2014-10-01

... with architect-engineer firms. 2936.209 Section 2936.209 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL CONTRACTING REQUIREMENTS CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 2936.209 Construction contracts with architect-engineer firms. As...

48 CFR 1536.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2013 CFR

2013-10-01

... with architect-engineer firms. 1536.209 Section 1536.209 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 1536.209 Construction contracts with architect-engineer...

48 CFR 436.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... with architect-engineer firms. 436.209 Section 436.209 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 436.209 Construction contracts with architect-engineer...

48 CFR 436.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2012 CFR

2012-10-01

... with architect-engineer firms. 436.209 Section 436.209 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 436.209 Construction contracts with architect-engineer...

48 CFR 2936.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... with architect-engineer firms. 2936.209 Section 2936.209 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL CONTRACTING REQUIREMENTS CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 2936.209 Construction contracts with architect-engineer firms. As...

48 CFR 436.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... with architect-engineer firms. 436.209 Section 436.209 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 436.209 Construction contracts with architect-engineer...

48 CFR 1436.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2014 CFR

2014-10-01

... with architect-engineer firms. 1436.209 Section 1436.209 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 1436.209 Construction contracts with architect-engineer...

48 CFR 1536.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... with architect-engineer firms. 1536.209 Section 1536.209 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 1536.209 Construction contracts with architect-engineer...

48 CFR 1536.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2012 CFR

2012-10-01

... with architect-engineer firms. 1536.209 Section 1536.209 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 1536.209 Construction contracts with architect-engineer...

48 CFR 1536.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... architect-engineer firms. 1536.209 Section 1536.209 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 1536.209 Construction contracts with architect-engineer firms. (a...

48 CFR 2936.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... with architect-engineer firms. 2936.209 Section 2936.209 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL CONTRACTING REQUIREMENTS CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 2936.209 Construction contracts with architect-engineer firms. As...

48 CFR 1436.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2013 CFR

2013-10-01

... with architect-engineer firms. 1436.209 Section 1436.209 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 1436.209 Construction contracts with architect-engineer...

48 CFR 2936.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2012 CFR

2012-10-01

... with architect-engineer firms. 2936.209 Section 2936.209 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL CONTRACTING REQUIREMENTS CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 2936.209 Construction contracts with architect-engineer firms. As...

48 CFR 1536.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2014 CFR

2014-10-01

... with architect-engineer firms. 1536.209 Section 1536.209 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 1536.209 Construction contracts with architect-engineer...

40 CFR 240.209 - Safety.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Safety. 240.209 Section 240.209 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.209 Safety. ...

48 CFR 253.209 - Contractor qualifications.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contractor qualifications. 253.209 Section 253.209 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS FORMS Prescription of Forms 253.209 Contractor qualifications. ...

48 CFR 1553.209-70 - EPA Form 1900-26, Contracting Officer's Evaluation of Contractor Performance.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., Contracting Officer's Evaluation of Contractor Performance. 1553.209-70 Section 1553.209-70 Federal... 1553.209-70 EPA Form 1900-26, Contracting Officer's Evaluation of Contractor Performance. As prescribed... evaluation of Contractor performance. ...

14 CFR 67.209 - Neurologic.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Neurologic. 67.209 Section 67.209... STANDARDS AND CERTIFICATION Second-Class Airman Medical Certificate § 67.209 Neurologic. Neurologic... neurologic condition that the Federal Air Surgeon, based on the case history and appropriate, qualified...

14 CFR 67.209 - Neurologic.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Neurologic. 67.209 Section 67.209... STANDARDS AND CERTIFICATION Second-Class Airman Medical Certificate § 67.209 Neurologic. Neurologic... neurologic condition that the Federal Air Surgeon, based on the case history and appropriate, qualified...

7 CFR 868.209 - Information.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 7 2012-01-01 2012-01-01 false Information. 868.209 Section 868.209 Agriculture... Application of Standards § 868.209 Information. Requests for the Rice Inspection Handbook, Equipment Handbook, or for information concerning approved devices and procedures, criteria for approved devices, and...

7 CFR 868.209 - Information.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 7 2013-01-01 2013-01-01 false Information. 868.209 Section 868.209 Agriculture... Application of Standards § 868.209 Information. Requests for the Rice Inspection Handbook, Equipment Handbook, or for information concerning approved devices and procedures, criteria for approved devices, and...

7 CFR 868.209 - Information.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 7 2011-01-01 2011-01-01 false Information. 868.209 Section 868.209 Agriculture... Application of Standards § 868.209 Information. Requests for the Rice Inspection Handbook, Equipment Handbook, or for information concerning approved devices and procedures, criteria for approved devices, and...

7 CFR 868.209 - Information.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 7 2014-01-01 2014-01-01 false Information. 868.209 Section 868.209 Agriculture... Application of Standards § 868.209 Information. Requests for the Rice Inspection Handbook, Equipment Handbook, or for information concerning approved devices and procedures, criteria for approved devices, and...

23 CFR 650.209 - Construction.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false Construction. 650.209 Section 650.209 Highways FEDERAL..., STRUCTURES, AND HYDRAULICS Erosion and Sediment Control on Highway Construction Projects § 650.209 Construction. (a) Permanent erosion and sediment control measures and practices shall be established and...

23 CFR 650.209 - Construction.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 23 Highways 1 2013-04-01 2013-04-01 false Construction. 650.209 Section 650.209 Highways FEDERAL..., STRUCTURES, AND HYDRAULICS Erosion and Sediment Control on Highway Construction Projects § 650.209 Construction. (a) Permanent erosion and sediment control measures and practices shall be established and...

23 CFR 650.209 - Construction.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 23 Highways 1 2014-04-01 2014-04-01 false Construction. 650.209 Section 650.209 Highways FEDERAL..., STRUCTURES, AND HYDRAULICS Erosion and Sediment Control on Highway Construction Projects § 650.209 Construction. (a) Permanent erosion and sediment control measures and practices shall be established and...

23 CFR 650.209 - Construction.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 23 Highways 1 2012-04-01 2012-04-01 false Construction. 650.209 Section 650.209 Highways FEDERAL..., STRUCTURES, AND HYDRAULICS Erosion and Sediment Control on Highway Construction Projects § 650.209 Construction. (a) Permanent erosion and sediment control measures and practices shall be established and...

23 CFR 650.209 - Construction.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false Construction. 650.209 Section 650.209 Highways FEDERAL..., STRUCTURES, AND HYDRAULICS Erosion and Sediment Control on Highway Construction Projects § 650.209 Construction. (a) Permanent erosion and sediment control measures and practices shall be established and...

7 CFR 868.209 - Information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 7 2010-01-01 2010-01-01 false Information. 868.209 Section 868.209 Agriculture... Application of Standards § 868.209 Information. Requests for the Rice Inspection Handbook, Equipment Handbook, or for information concerning approved devices and procedures, criteria for approved devices, and...

49 CFR 399.209 - Test procedures.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 5 2011-10-01 2011-10-01 false Test procedures. 399.209 Section 399.209 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY... STANDARDS Step, Handhold, and Deck Requirements for Commercial Motor Vehicles § 399.209 Test procedures. (a...

20 CFR 209.11 - Employee representatives' reports.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Employee representatives' reports. 209.11 Section 209.11 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT RAILROAD EMPLOYERS' REPORTS AND RESPONSIBILITIES § 209.11 Employee representatives' reports. An individual...

49 CFR 209.313 - Discovery.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Discovery. 209.313 Section 209.313 Transportation... TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Disqualification Procedures § 209.313 Discovery. (a... parties. Discovery is designed to enable a party to obtain relevant information needed for preparation of...

49 CFR 209.313 - Discovery.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Discovery. 209.313 Section 209.313 Transportation... TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Disqualification Procedures § 209.313 Discovery. (a... parties. Discovery is designed to enable a party to obtain relevant information needed for preparation of...

49 CFR 209.313 - Discovery.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Discovery. 209.313 Section 209.313 Transportation... TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Disqualification Procedures § 209.313 Discovery. (a... parties. Discovery is designed to enable a party to obtain relevant information needed for preparation of...

49 CFR 209.313 - Discovery.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Discovery. 209.313 Section 209.313 Transportation... TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Disqualification Procedures § 209.313 Discovery. (a... parties. Discovery is designed to enable a party to obtain relevant information needed for preparation of...

48 CFR 36.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2013 CFR

2013-10-01

... with architect-engineer firms. 36.209 Section 36.209 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 36.209 Construction contracts with architect-engineer firms. No...

48 CFR 636.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2013 CFR

2013-10-01

... with architect-engineer firms. 636.209 Section 636.209 Federal Acquisition Regulations System DEPARTMENT OF STATE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 636.209 Construction contracts with architect-engineer firms. The...

48 CFR 636.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2014 CFR

2014-10-01

... with architect-engineer firms. 636.209 Section 636.209 Federal Acquisition Regulations System DEPARTMENT OF STATE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 636.209 Construction contracts with architect-engineer firms. The...

48 CFR 636.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... with architect-engineer firms. 636.209 Section 636.209 Federal Acquisition Regulations System DEPARTMENT OF STATE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 636.209 Construction contracts with architect-engineer firms. The...

48 CFR 636.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2012 CFR

2012-10-01

... with architect-engineer firms. 636.209 Section 636.209 Federal Acquisition Regulations System DEPARTMENT OF STATE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 636.209 Construction contracts with architect-engineer firms. The...

48 CFR 36.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... with architect-engineer firms. 36.209 Section 36.209 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 36.209 Construction contracts with architect-engineer firms. No...

48 CFR 636.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... with architect-engineer firms. 636.209 Section 636.209 Federal Acquisition Regulations System DEPARTMENT OF STATE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 636.209 Construction contracts with architect-engineer firms. The...

48 CFR 2936.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2013 CFR

2013-10-01

... architect-engineer firms. 2936.209 Section 2936.209 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL CONTRACTING REQUIREMENTS CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 2936.209 Construction contracts with architect-engineer firms. As required by FAR...

48 CFR 36.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... with architect-engineer firms. 36.209 Section 36.209 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 36.209 Construction contracts with architect-engineer firms. No...

48 CFR 36.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2012 CFR

2012-10-01

... with architect-engineer firms. 36.209 Section 36.209 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 36.209 Construction contracts with architect-engineer firms. No...

48 CFR 36.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2014 CFR

2014-10-01

... with architect-engineer firms. 36.209 Section 36.209 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 36.209 Construction contracts with architect-engineer firms. No...

47 CFR 54.209 - Annual reporting requirements for designated eligible telecommunications carriers.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 3 2010-10-01 2010-10-01 false Annual reporting requirements for designated eligible telecommunications carriers. 54.209 Section 54.209 Telecommunication FEDERAL COMMUNICATIONS... Service Support § 54.209 Annual reporting requirements for designated eligible telecommunications carriers...

47 CFR 54.209 - Annual reporting requirements for designated eligible telecommunications carriers.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 3 2011-10-01 2011-10-01 false Annual reporting requirements for designated eligible telecommunications carriers. 54.209 Section 54.209 Telecommunication FEDERAL COMMUNICATIONS... Service Support § 54.209 Annual reporting requirements for designated eligible telecommunications carriers...

49 CFR 209.313 - Discovery.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Discovery. 209.313 Section 209.313 Transportation... TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Disqualification Procedures § 209.313 Discovery. (a... parties. Discovery is designed to enable a party to obtain relevant information needed for preparation of...

47 CFR 76.209 - Fairness doctrine; personal attacks; political editorials.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 4 2010-10-01 2010-10-01 false Fairness doctrine; personal attacks; political editorials. 76.209 Section 76.209 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Cablecasting § 76.209 Fairness doctrine...

Decabrominated Diphenyl Ethers (BDE-209) in Chinese and Global Air: Levels, Gas/Particle Partitioning, and Long-Range Transport: Is Long-Range Transport of BDE-209 Really Governed by the Movement of Particles?

PubMed

Li, Yi-Fan; Qiao, Li-Na; Ren, Nan-Qi; Sverko, Ed; Mackay, Donald; Macdonald, Robie W

2017-01-17

In this paper, we report air concentrations of BDE-209 in both gas- and particle-phases across China. The annual mean concentrations of BDE-209 were from below detection limit (BDL) to 77.0 pg·m -3 in the gas-phase and 1.06-728 pg·m -3 in the particle-phase. Among the nine PBDEs measured, BDE-209 is the dominant congener in Chinese atmosphere in both gas and particle phases. We predicted the partitioning behavior of BDE-209 in air using our newly developed steady state equation, and the results matched the monitoring data worldwide very well. It was found that the logarithm of the partition quotient of BDE-209 is a constant, and equal to -1.53 under the global ambient temperature range (from -50 to +50 °C). The gaseous fractions of BDE-209 in air depends on the concentration of total suspended particle (TSP). The most important conclusion derived from this study is that, BDE-209, like other semivolatile organic compounds (SVOCs), cannot be sorbed entirely to atmospheric particles; and there is a significant amount of gaseous BDE-209 in global atmosphere, which is subject to long-range atmospheric transport (LRAT). Therefore, it is not surprising that BDE-209 can enter the Arctic through LRAT mainly by air transport rather than by particle movement. This is a significant advancement in understanding the global transport process and the pathways entering the Arctic for chemicals with low volatility and high octanol-air partition coefficients, such as BDE-209.

49 CFR 190.209 - Response options.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 3 2010-10-01 2010-10-01 false Response options. 190.209 Section 190.209 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... PROCEDURES Enforcement § 190.209 Response options. Within 30 days of receipt of a notice of probable...

48 CFR 209.106 - Preaward surveys.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Preaward surveys. 209.106 Section 209.106 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... Preaward surveys. When requesting a preawared survey, follow the procedures at PGI 209.106. [69 FR 65089...

48 CFR 209.106 - Preaward surveys.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Preaward surveys. 209.106 Section 209.106 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... Preaward surveys. When requesting a preawared survey, follow the procedures at PGI 209.106. [69 FR 65089...

48 CFR 209.106 - Preaward surveys.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Preaward surveys. 209.106 Section 209.106 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... Preaward surveys. When requesting a preawared survey, follow the procedures at PGI 209.106. [69 FR 65089...

48 CFR 209.106 - Preaward surveys.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Preaward surveys. 209.106 Section 209.106 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... Preaward surveys. When requesting a preawared survey, follow the procedures at PGI 209.106. [69 FR 65089...

48 CFR 209.106 - Preaward surveys.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Preaward surveys. 209.106 Section 209.106 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... Preaward surveys. When requesting a preawared survey, follow the procedures at PGI 209.106. [69 FR 65089...

34 CFR 668.209 - Uncorrected data adjustments.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 3 2010-07-01 2010-07-01 false Uncorrected data adjustments. 668.209 Section 668.209 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION STUDENT ASSISTANCE GENERAL PROVISIONS Cohort Default Rates § 668.209...

48 CFR 253.209-1 - Responsible prospective contractors.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Responsible prospective contractors. 253.209-1 Section 253.209-1 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS FORMS Prescription of Forms 253.209-1 Responsible...

48 CFR 253.209-1 - Responsible prospective contractors.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Responsible prospective contractors. 253.209-1 Section 253.209-1 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS FORMS Prescription of Forms 253.209-1 Responsible...

48 CFR 1815.209-70 - NASA solicitation provisions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true NASA solicitation provisions. 1815.209-70 Section 1815.209-70 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND... Receipt of Proposals and Information 1815.209-70 NASA solicitation provisions. (a) The contracting officer...

48 CFR 1815.209-70 - NASA solicitation provisions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false NASA solicitation provisions. 1815.209-70 Section 1815.209-70 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND... Receipt of Proposals and Information 1815.209-70 NASA solicitation provisions. (a) The contracting officer...

48 CFR 1815.209-70 - NASA solicitation provisions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false NASA solicitation provisions. 1815.209-70 Section 1815.209-70 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND... Receipt of Proposals and Information 1815.209-70 NASA solicitation provisions. (a) The contracting officer...

48 CFR 1815.209-70 - NASA solicitation provisions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false NASA solicitation provisions. 1815.209-70 Section 1815.209-70 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND... Receipt of Proposals and Information 1815.209-70 NASA solicitation provisions. (a) The contracting officer...

48 CFR 1815.209-70 - NASA solicitation provisions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false NASA solicitation provisions. 1815.209-70 Section 1815.209-70 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND... Receipt of Proposals and Information 1815.209-70 NASA solicitation provisions. (a) The contracting officer...

10 CFR 209.3 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Definitions. 209.3 Section 209.3 Energy DEPARTMENT OF ENERGY OIL INTERNATIONAL VOLUNTARY AGREEMENTS General Provisions § 209.3 Definitions. For purposes of... Agency established by Decision of the Council of the Organization for Economic Cooperation and...

20 CFR 209.16 - Disposal of payroll records.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Disposal of payroll records. 209.16 Section 209.16 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT RAILROAD EMPLOYERS' REPORTS AND RESPONSIBILITIES § 209.16 Disposal of payroll records. Employers may...

46 CFR 169.209 - Routes permitted.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 7 2011-10-01 2011-10-01 false Routes permitted. 169.209 Section 169.209 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Inspection and Certification Certificate of Inspection § 169.209 Routes permitted. (a) The area of operation for...

46 CFR 169.209 - Routes permitted.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Routes permitted. 169.209 Section 169.209 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Inspection and Certification Certificate of Inspection § 169.209 Routes permitted. (a) The area of operation for...

49 CFR 209.17 - Motions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... officer. Each motion shall state the particular order, ruling, or action desired and the grounds therefor... 49 Transportation 4 2011-10-01 2011-10-01 false Motions. 209.17 Section 209.17 Transportation... TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES General § 209.17 Motions. Motions shall be in writing...

49 CFR 209.17 - Motions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... officer. Each motion shall state the particular order, ruling, or action desired and the grounds therefor... 49 Transportation 4 2010-10-01 2010-10-01 false Motions. 209.17 Section 209.17 Transportation... TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES General § 209.17 Motions. Motions shall be in writing...

7 CFR 1744.209 - Records.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 11 2014-01-01 2014-01-01 false Records. 1744.209 Section 1744.209 Agriculture... § 1744.209 Records. (a) The records of borrowers, including records relating to qualified investments... right to review the records of the borrower relating to qualified investments to determine if the...

7 CFR 1744.209 - Records.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 11 2011-01-01 2011-01-01 false Records. 1744.209 Section 1744.209 Agriculture... § 1744.209 Records. (a) The records of borrowers, including records relating to qualified investments... right to review the records of the borrower relating to qualified investments to determine if the...

7 CFR 1744.209 - Records.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 11 2013-01-01 2013-01-01 false Records. 1744.209 Section 1744.209 Agriculture... § 1744.209 Records. (a) The records of borrowers, including records relating to qualified investments... right to review the records of the borrower relating to qualified investments to determine if the...

7 CFR 1744.209 - Records.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 11 2012-01-01 2012-01-01 false Records. 1744.209 Section 1744.209 Agriculture... § 1744.209 Records. (a) The records of borrowers, including records relating to qualified investments... right to review the records of the borrower relating to qualified investments to determine if the...

7 CFR 1744.209 - Records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 11 2010-01-01 2010-01-01 false Records. 1744.209 Section 1744.209 Agriculture... § 1744.209 Records. (a) The records of borrowers, including records relating to qualified investments... right to review the records of the borrower relating to qualified investments to determine if the...

40 CFR 209.16 - Late intervention.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Late intervention. 209.16 Section 209.16 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS... Hearings for Orders Issued Under Section 11(d) of the Noise Control Act § 209.16 Late intervention...

40 CFR 209.16 - Late intervention.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Late intervention. 209.16 Section 209.16 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS... Hearings for Orders Issued Under Section 11(d) of the Noise Control Act § 209.16 Late intervention...

40 CFR 209.16 - Late intervention.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Late intervention. 209.16 Section 209.16 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS... Hearings for Orders Issued Under Section 11(d) of the Noise Control Act § 209.16 Late intervention...

40 CFR 209.16 - Late intervention.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Late intervention. 209.16 Section 209.16 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS... Hearings for Orders Issued Under Section 11(d) of the Noise Control Act § 209.16 Late intervention...

40 CFR 209.16 - Late intervention.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Late intervention. 209.16 Section 209.16 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS... Hearings for Orders Issued Under Section 11(d) of the Noise Control Act § 209.16 Late intervention...

49 CFR 209.103 - Minimum and maximum penalties.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Minimum and maximum penalties. 209.103 Section 209... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Hazardous Materials Penalties Civil Penalties § 209.103 Minimum and maximum penalties. (a) A person who knowingly violates a...

49 CFR 209.103 - Minimum and maximum penalties.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Minimum and maximum penalties. 209.103 Section 209... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Hazardous Materials Penalties Civil Penalties § 209.103 Minimum and maximum penalties. (a) A person who knowingly violates a...

49 CFR 209.103 - Minimum and maximum penalties.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Minimum and maximum penalties. 209.103 Section 209... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Hazardous Materials Penalties Civil Penalties § 209.103 Minimum and maximum penalties. (a) A person who knowingly violates a...

49 CFR 209.103 - Minimum and maximum penalties.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Minimum and maximum penalties. 209.103 Section 209... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Hazardous Materials Penalties Civil Penalties § 209.103 Minimum and maximum penalties. (a) A person who knowingly violates a...

49 CFR 209.103 - Minimum and maximum penalties.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Minimum and maximum penalties. 209.103 Section 209... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Hazardous Materials Penalties Civil Penalties § 209.103 Minimum and maximum penalties. (a) A person who knowingly violates a...

Evaluation of 209At as a theranostic isotope for 209At-radiopharmaceutical development using high-energy SPECT

NASA Astrophysics Data System (ADS)

Crawford, J. R.; Robertson, A. K. H.; Yang, H.; Rodríguez-Rodríguez, C.; Esquinas, P. L.; Kunz, P.; Blinder, S.; Sossi, V.; Schaffer, P.; Ruth, T. J.

2018-02-01

The development of alpha-emitting radiopharmaceuticals using 211At requires quantitative determination of the time-dependent nature of the 211At biodistribution. However, imaging-based methods for acquiring this information with 211At have not found wide-spread use because of its low abundance of decay emissions suitable for external detection. In this publication we demonstrate the theranostic abilities of the 211At/209At isotope pair and present the first-ever 209At SPECT images. The VECTor microSPECT/PET/CT scanner was used to image 209At with a collimator suitable for the 511 keV annihilation photons of PET isotopes. Data from distinct photopeaks of the 209At energy spectrum (195 keV (22.6%), 239 keV (12.4 %), 545 keV (91.0 %), a combined 782/790 keV peak (147 %), and 209Po x-rays (139.0 %)) were independently evaluated for use in image reconstructions using Monte Carlo (GATE) simulations and phantom studies. 209At-imaging in vivo was demonstrated in a healthy mouse injected with 10 MBq of free [209At]astatide. Image-based measurements of 209At uptake in organs of interest—acquired in 5 min intervals—were compared to ex vivo gamma counter measurements of the same organs. Simulated and measured data indicated that—due to the large amount of scatter from high energy (>750 keV) gammas—reconstructed images using the x-ray peak outperformed those obtained from other peaks in terms of image uniformity and spatial resolution, determined to be  <0.85 mm. 209At imaging using the x-ray peak revealed a biodistribution that matched the known distribution of free astatide, and in vivo image-based measurements of 209At uptake in organs of interest matched ex vivo measurements within 10%. We have acquired the first 209At SPECT images and demonstrated the ability of quantitative SPECT imaging with 209At to accurately determine astatine biodistributions with high spatial and temporal resolution.

46 CFR 109.209 - Appliances for watertight integrity.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Appliances for watertight integrity. 109.209 Section 109.209 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Tests, Drills, and Inspections § 109.209 Appliances for watertight integrity. (a) Before getting...

46 CFR 109.209 - Appliances for watertight integrity.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Appliances for watertight integrity. 109.209 Section 109.209 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Tests, Drills, and Inspections § 109.209 Appliances for watertight integrity. (a) Before getting...

46 CFR 109.209 - Appliances for watertight integrity.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Appliances for watertight integrity. 109.209 Section 109.209 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Tests, Drills, and Inspections § 109.209 Appliances for watertight integrity. (a) Before getting...

46 CFR 109.209 - Appliances for watertight integrity.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Appliances for watertight integrity. 109.209 Section 109.209 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Tests, Drills, and Inspections § 109.209 Appliances for watertight integrity. (a) Before getting...

46 CFR 109.209 - Appliances for watertight integrity.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Appliances for watertight integrity. 109.209 Section 109.209 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Tests, Drills, and Inspections § 109.209 Appliances for watertight integrity. (a) Before getting...

49 CFR 209.115 - Hearing.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Hearing. 209.115 Section 209.115 Transportation... Hearing. (a) When a hearing is requested and scheduled under § 209.113, a hearing officer designated by the Chief Counsel convenes and presides over the hearing. If requested by respondent and if...

18 CFR 706.209 - Gambling, betting, and lotteries.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 2 2012-04-01 2012-04-01 false Gambling, betting, and lotteries. 706.209 Section 706.209 Conservation of Power and Water Resources WATER RESOURCES COUNCIL EMPLOYEE RESPONSIBILITIES AND CONDUCT Conduct and Responsibilities of Employees § 706.209 Gambling, betting...

48 CFR 209.571-6 - Identification of organizational conflicts of interest.

Code of Federal Regulations, 2011 CFR

2011-10-01

... organizational conflicts of interest. 209.571-6 Section 209.571-6 Federal Acquisition Regulations System DEFENSE... Organizational and Consultant Conflicts of Interest 209.571-6 Identification of organizational conflicts of interest. When evaluating organizational conflicts of interest for major defense acquisition programs or...

24 CFR 570.209 - Guidelines for evaluating and selecting economic development projects.

Code of Federal Regulations, 2010 CFR

2010-04-01

... selecting economic development projects. 570.209 Section 570.209 Housing and Urban Development Regulations... DEVELOPMENT BLOCK GRANTS Eligible Activities § 570.209 Guidelines for evaluating and selecting economic... activities to be carried out for economic development purposes. Specifically, these guidelines are applicable...

42 CFR 93.209 - Funding component.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Funding component. 93.209 Section 93.209 Public... EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Definitions § 93.209 Funding component. Funding component means any organizational unit of the PHS...

42 CFR 93.209 - Funding component.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Funding component. 93.209 Section 93.209 Public... EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Definitions § 93.209 Funding component. Funding component means any organizational unit of the PHS...

42 CFR 93.209 - Funding component.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Funding component. 93.209 Section 93.209 Public... EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Definitions § 93.209 Funding component. Funding component means any organizational unit of the PHS...

42 CFR 93.209 - Funding component.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Funding component. 93.209 Section 93.209 Public... EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Definitions § 93.209 Funding component. Funding component means any organizational unit of the PHS...

42 CFR 93.209 - Funding component.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Funding component. 93.209 Section 93.209 Public... EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Definitions § 93.209 Funding component. Funding component means any organizational unit of the PHS...

30 CFR 71.209 - Respirable dust samples; transmission by operator.

Code of Federal Regulations, 2012 CFR

2012-07-01

... operator. 71.209 Section 71.209 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY HEALTH STANDARDS-SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES Sampling Procedures § 71.209 Respirable dust samples; transmission by...

30 CFR 71.209 - Respirable dust samples; transmission by operator.

Code of Federal Regulations, 2013 CFR

2013-07-01

... operator. 71.209 Section 71.209 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY HEALTH STANDARDS-SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES Sampling Procedures § 71.209 Respirable dust samples; transmission by...

30 CFR 71.209 - Respirable dust samples; transmission by operator.

Code of Federal Regulations, 2014 CFR

2014-07-01

... operator. 71.209 Section 71.209 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY HEALTH STANDARDS-SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES Sampling Procedures § 71.209 Respirable dust samples; transmission by...

50 CFR 226.209 - Critical habitat for hawksbill turtle.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Critical habitat for hawksbill turtle. 226.209 Section 226.209 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS DESIGNATED CRITICAL HABITAT § 226.209...

50 CFR 226.209 - Critical habitat for hawksbill turtle.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 50 Wildlife and Fisheries 10 2012-10-01 2012-10-01 false Critical habitat for hawksbill turtle. 226.209 Section 226.209 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS DESIGNATED CRITICAL HABITAT § 226.209...

47 CFR 27.209 - Designated entities; bidding credits; unjust enrichment.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false Designated entities; bidding credits; unjust enrichment. 27.209 Section 27.209 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON... 2305-2320 MHz and 2345-2360 MHz Bands § 27.209 Designated entities; bidding credits; unjust enrichment...

33 CFR 209.335 - Publication.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Publication. 209.335 Section 209... ADMINISTRATIVE PROCEDURE § 209.335 Publication. (a) Section 4 of the Administrative Procedure Act requires publication of general notice of proposed rule making in the Federal Register (unless all persons subject...

22 CFR 209.6 - Compliance information.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Compliance information. 209.6 Section 209.6... § 209.6 Compliance information. (a) Cooperation and assistance. The Administrator shall to the fullest... and accurate compliance reports at such times, and in such form and containing such information, as...

48 CFR 415.209 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Solicitation provisions and contract clauses. 415.209 Section 415.209 Federal Acquisition Regulations System DEPARTMENT OF... Proposals and Information 415.209 Solicitation provisions and contract clauses. (a) The provision at 452.215...

22 CFR 209.4 - Discrimination prohibited.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Discrimination prohibited. 209.4 Section 209.4 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT NON-DISCRIMINATION IN FEDERALLY-ASSISTED PROGRAMS... § 209.4 Discrimination prohibited. (a) General. No person in the United States shall, on the grounds of...

22 CFR 209.4 - Discrimination prohibited.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Discrimination prohibited. 209.4 Section 209.4 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT NON-DISCRIMINATION IN FEDERALLY-ASSISTED PROGRAMS... § 209.4 Discrimination prohibited. (a) General. No person in the United States shall, on the grounds of...

22 CFR 209.4 - Discrimination prohibited.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Discrimination prohibited. 209.4 Section 209.4 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT NON-DISCRIMINATION IN FEDERALLY-ASSISTED PROGRAMS... § 209.4 Discrimination prohibited. (a) General. No person in the United States shall, on the grounds of...

22 CFR 209.4 - Discrimination prohibited.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Discrimination prohibited. 209.4 Section 209.4 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT NON-DISCRIMINATION IN FEDERALLY-ASSISTED PROGRAMS... § 209.4 Discrimination prohibited. (a) General. No person in the United States shall, on the grounds of...

24 CFR 570.209 - Guidelines for evaluating and selecting economic development projects.

Code of Federal Regulations, 2012 CFR

2012-04-01

... selecting economic development projects. 570.209 Section 570.209 Housing and Urban Development Regulations... DEVELOPMENT BLOCK GRANTS Eligible Activities § 570.209 Guidelines for evaluating and selecting economic... activities to be carried out for economic development purposes. Specifically, these guidelines are applicable...

28 CFR 5.209 - Information relating to employees.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Information relating to employees. 5.209 Section 5.209 Judicial Administration DEPARTMENT OF JUSTICE ADMINISTRATION AND ENFORCEMENT OF FOREIGN AGENTS REGISTRATION ACT OF 1938, AS AMENDED § 5.209 Information relating to employees. A registrant shall...

49 CFR 209.115 - Hearing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Hearing. 209.115 Section 209.115 Transportation... Hearing. (a) When a hearing is requested and scheduled under § 209.113, a hearing officer designated by the Chief Counsel convenes and presides over the hearing. If requested by respondent and if...

5 CFR 930.209 - Senior Administrative Law Judge Program.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Senior Administrative Law Judge Program. 930.209 Section 930.209 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL...) Administrative Law Judge Program § 930.209 Senior Administrative Law Judge Program. (a) OPM administers a Senior...

5 CFR 930.209 - Senior Administrative Law Judge Program.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Senior Administrative Law Judge Program. 930.209 Section 930.209 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL...) Administrative Law Judge Program § 930.209 Senior Administrative Law Judge Program. (a) OPM administers a Senior...

5 CFR 930.209 - Senior Administrative Law Judge Program.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Senior Administrative Law Judge Program. 930.209 Section 930.209 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL...) Administrative Law Judge Program § 930.209 Senior Administrative Law Judge Program. (a) OPM administers a Senior...

10 CFR 209.2 - Delegation.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 3 2011-01-01 2011-01-01 false Delegation. 209.2 Section 209.2 Energy DEPARTMENT OF ENERGY OIL INTERNATIONAL VOLUNTARY AGREEMENTS General Provisions § 209.2 Delegation. To the extent otherwise permitted by law, any authority, duty, or responsibility vested in DOE or the Administrator under...

10 CFR 209.2 - Delegation.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Delegation. 209.2 Section 209.2 Energy DEPARTMENT OF ENERGY OIL INTERNATIONAL VOLUNTARY AGREEMENTS General Provisions § 209.2 Delegation. To the extent otherwise permitted by law, any authority, duty, or responsibility vested in DOE or the Administrator under...

48 CFR 52.209-5 - Certification Regarding Responsibility Matters.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Responsibility Matters. 52.209-5 Section 52.209-5 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.209-5 Certification Regarding Responsibility Matters. As prescribed in 9.104-7(a), insert the following provision: Certification Regarding Responsibility Matters (APR 2010) (a)(1) The Offeror certifies...

48 CFR 52.209-5 - Certification Regarding Responsibility Matters.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Responsibility Matters. 52.209-5 Section 52.209-5 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.209-5 Certification Regarding Responsibility Matters. As prescribed in 9.104-7(a), insert the following provision: Certification Regarding Responsibility Matters (APR 2010) (a)(1) The Offeror certifies...

48 CFR 52.209-5 - Certification Regarding Responsibility Matters.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Responsibility Matters. 52.209-5 Section 52.209-5 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.209-5 Certification Regarding Responsibility Matters. As prescribed in 9.104-7(a), insert the following provision: Certification Regarding Responsibility Matters (APR 2010) (a)(1) The Offeror certifies...

48 CFR 52.209-7 - Information Regarding Responsibility Matters.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Responsibility Matters. 52.209-7 Section 52.209-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.209-7 Information Regarding Responsibility Matters. As prescribed at 9.104-7(b), insert the following provision: Information Regarding Responsibility Matters (JUL 2013) (a) Definitions. As used in...

48 CFR 52.209-7 - Information Regarding Responsibility Matters.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Responsibility Matters. 52.209-7 Section 52.209-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.209-7 Information Regarding Responsibility Matters. As prescribed at 9.104-7(b), insert the following provision: Information Regarding Responsibility Matters (JUL 2013) (a) Definitions. As used in...

48 CFR 52.209-7 - Information Regarding Responsibility Matters.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Responsibility Matters. 52.209-7 Section 52.209-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.209-7 Information Regarding Responsibility Matters. As prescribed at 9.104-7(b), insert the following provision: Information Regarding Responsibility Matters (FEB 2012) (a) Definitions. As used in...

48 CFR 52.209-5 - Certification Regarding Responsibility Matters.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Responsibility Matters. 52.209-5 Section 52.209-5 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.209-5 Certification Regarding Responsibility Matters. As prescribed in 9.104-7(a), insert the following provision: Certification Regarding Responsibility Matters (APR 2010) (a)(1) The Offeror certifies...

50 CFR 665.209 - Fishing moratorium at Hancock Seamounts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 50 Wildlife and Fisheries 13 2014-10-01 2014-10-01 false Fishing moratorium at Hancock Seamounts. 665.209 Section 665.209 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC... Hawaii Fisheries § 665.209 Fishing moratorium at Hancock Seamounts. Fishing for, and possession of...

50 CFR 665.209 - Fishing moratorium at Hancock Seamounts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 50 Wildlife and Fisheries 13 2012-10-01 2012-10-01 false Fishing moratorium at Hancock Seamounts. 665.209 Section 665.209 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC... Hawaii Fisheries § 665.209 Fishing moratorium at Hancock Seamounts. Fishing for, and possession of...

50 CFR 665.209 - Fishing moratorium at Hancock Seamounts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Fishing moratorium at Hancock Seamounts. 665.209 Section 665.209 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC... Hawaii Fisheries § 665.209 Fishing moratorium at Hancock Seamounts. Fishing for, and possession of...

50 CFR 665.209 - Fishing moratorium at Hancock Seamounts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 50 Wildlife and Fisheries 13 2013-10-01 2013-10-01 false Fishing moratorium at Hancock Seamounts. 665.209 Section 665.209 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC... Hawaii Fisheries § 665.209 Fishing moratorium at Hancock Seamounts. Fishing for, and possession of...

50 CFR 665.209 - Fishing moratorium on Hancock Seamount.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Fishing moratorium on Hancock Seamount. 665.209 Section 665.209 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC... Hawaii Fisheries § 665.209 Fishing moratorium on Hancock Seamount. Fishing for Hawaii bottomfish and...

48 CFR 2052.209-71 - Contractor organizational conflicts of interest (representation).

Code of Federal Regulations, 2010 CFR

2010-10-01

... conflicts of interest (representation). 2052.209-71 Section 2052.209-71 Federal Acquisition Regulations... of Provisions and Clauses 2052.209-71 Contractor organizational conflicts of interest (representation... Organizational Conflicts of Interest Representation (OCT 1999) I represent to the best of my knowledge and belief...

18 CFR 706.209 - Gambling, betting, and lotteries.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Gambling, betting, and lotteries. 706.209 Section 706.209 Conservation of Power and Water Resources WATER RESOURCES COUNCIL EMPLOYEE RESPONSIBILITIES AND CONDUCT Conduct and Responsibilities of Employees § 706.209 Gambling, betting...

18 CFR 706.209 - Gambling, betting, and lotteries.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Gambling, betting, and lotteries. 706.209 Section 706.209 Conservation of Power and Water Resources WATER RESOURCES COUNCIL EMPLOYEE RESPONSIBILITIES AND CONDUCT Conduct and Responsibilities of Employees § 706.209 Gambling, betting...

18 CFR 706.209 - Gambling, betting, and lotteries.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 2 2013-04-01 2012-04-01 true Gambling, betting, and lotteries. 706.209 Section 706.209 Conservation of Power and Water Resources WATER RESOURCES COUNCIL EMPLOYEE RESPONSIBILITIES AND CONDUCT Conduct and Responsibilities of Employees § 706.209 Gambling, betting...

18 CFR 706.209 - Gambling, betting, and lotteries.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 2 2014-04-01 2014-04-01 false Gambling, betting, and lotteries. 706.209 Section 706.209 Conservation of Power and Water Resources WATER RESOURCES COUNCIL EMPLOYEE RESPONSIBILITIES AND CONDUCT Conduct and Responsibilities of Employees § 706.209 Gambling, betting...

33 CFR 209.345 - Water resource policies and authorities.

Code of Federal Regulations, 2013 CFR

2013-07-01

... authorities. 209.345 Section 209.345 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE ADMINISTRATIVE PROCEDURE § 209.345 Water resource policies and authorities... accomplishment by local interests, and (iii) periodic and final inspections. (3) The District Engineer will...

33 CFR 209.345 - Water resource policies and authorities.

Code of Federal Regulations, 2012 CFR

2012-07-01

... authorities. 209.345 Section 209.345 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE ADMINISTRATIVE PROCEDURE § 209.345 Water resource policies and authorities... accomplishment by local interests, and (iii) periodic and final inspections. (3) The District Engineer will...

33 CFR 209.345 - Water resource policies and authorities.

Code of Federal Regulations, 2011 CFR

2011-07-01

... authorities. 209.345 Section 209.345 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE ADMINISTRATIVE PROCEDURE § 209.345 Water resource policies and authorities... accomplishment by local interests, and (iii) periodic and final inspections. (3) The District Engineer will...

40 CFR 209.15 - Intervention.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Intervention. 209.15 Section 209.15 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS RULES OF... Orders Issued Under Section 11(d) of the Noise Control Act § 209.15 Intervention. (a) Persons desiring to...

40 CFR 209.15 - Intervention.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Intervention. 209.15 Section 209.15 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS RULES OF... Orders Issued Under Section 11(d) of the Noise Control Act § 209.15 Intervention. (a) Persons desiring to...

40 CFR 209.15 - Intervention.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Intervention. 209.15 Section 209.15 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS RULES OF... Orders Issued Under Section 11(d) of the Noise Control Act § 209.15 Intervention. (a) Persons desiring to...

40 CFR 209.15 - Intervention.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Intervention. 209.15 Section 209.15 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS RULES OF... Orders Issued Under Section 11(d) of the Noise Control Act § 209.15 Intervention. (a) Persons desiring to...

40 CFR 209.15 - Intervention.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Intervention. 209.15 Section 209.15 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS RULES OF... Orders Issued Under Section 11(d) of the Noise Control Act § 209.15 Intervention. (a) Persons desiring to...

33 CFR 209.335 - Publication.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Publication. 209.335 Section 209... ADMINISTRATIVE PROCEDURE § 209.335 Publication. (a) Section 4 of the Administrative Procedure Act requires publication of general notice of proposed rule making in the Federal Register (unless all persons subject...

33 CFR 209.335 - Publication.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Publication. 209.335 Section 209... ADMINISTRATIVE PROCEDURE § 209.335 Publication. (a) Section 4 of the Administrative Procedure Act requires publication of general notice of proposed rule making in the Federal Register (unless all persons subject...

33 CFR 209.335 - Publication.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Publication. 209.335 Section 209... ADMINISTRATIVE PROCEDURE § 209.335 Publication. (a) Section 4 of the Administrative Procedure Act requires publication of general notice of proposed rule making in the Federal Register (unless all persons subject...

33 CFR 209.335 - Publication.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Publication. 209.335 Section 209... ADMINISTRATIVE PROCEDURE § 209.335 Publication. (a) Section 4 of the Administrative Procedure Act requires publication of general notice of proposed rule making in the Federal Register (unless all persons subject...

48 CFR 53.209-1 - Responsible prospective contractors.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contractors. 53.209-1 Section 53.209-1 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.209-1 Responsible prospective contractors. (a) SF 1403 (Rev. 9/88), Preaward Survey of Prospective Contractor (General). SF 1403 is authorized for...

49 CFR 209.131 - Criminal penalties generally.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Criminal penalties generally. 209.131 Section 209... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Hazardous Materials Penalties Criminal Penalties § 209.131 Criminal penalties generally. A person who knowingly violates 49 U.S.C. 5104(b...

49 CFR 209.131 - Criminal penalties generally.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Criminal penalties generally. 209.131 Section 209... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Hazardous Materials Penalties Criminal Penalties § 209.131 Criminal penalties generally. A person who knowingly violates 49 U.S.C. 5104(b...

49 CFR 209.131 - Criminal penalties generally.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Criminal penalties generally. 209.131 Section 209... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Hazardous Materials Penalties Criminal Penalties § 209.131 Criminal penalties generally. A person who knowingly violates 49 U.S.C. 5104(b...

49 CFR 209.409 - Penalties.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., or has caused death or injury, a penalty not to exceed $100,000 per violation may be assessed. Each... 49 Transportation 4 2011-10-01 2011-10-01 false Penalties. 209.409 Section 209.409 Transportation... TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Reporting of Remedial Actions § 209.409 Penalties. Any...

49 CFR 209.131 - Criminal penalties generally.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Criminal penalties generally. 209.131 Section 209... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Hazardous Materials Penalties Criminal Penalties § 209.131 Criminal penalties generally. A person who knowingly violates 49 U.S.C. 5104(b...

49 CFR 209.409 - Penalties.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., or has caused death or injury, a penalty not to exceed $105,000 per violation may be assessed. Each... 49 Transportation 4 2012-10-01 2012-10-01 false Penalties. 209.409 Section 209.409 Transportation... TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Reporting of Remedial Actions § 209.409 Penalties. Any...

49 CFR 209.409 - Penalties.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., or has caused death or injury, a penalty not to exceed $105,000 per violation may be assessed. Each... 49 Transportation 4 2013-10-01 2013-10-01 false Penalties. 209.409 Section 209.409 Transportation... TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Reporting of Remedial Actions § 209.409 Penalties. Any...

49 CFR 209.131 - Criminal penalties generally.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Criminal penalties generally. 209.131 Section 209... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Hazardous Materials Penalties Criminal Penalties § 209.131 Criminal penalties generally. A person who knowingly violates 49 U.S.C. 5104(b...

49 CFR 209.409 - Penalties.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., or has caused death or injury, a penalty not to exceed $105,000 per violation may be assessed. Each... 49 Transportation 4 2014-10-01 2014-10-01 false Penalties. 209.409 Section 209.409 Transportation... TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Reporting of Remedial Actions § 209.409 Penalties. Any...

49 CFR 209.409 - Penalties.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., or has caused death or injury, a penalty not to exceed $100,000 per violation may be assessed. Each... 49 Transportation 4 2010-10-01 2010-10-01 false Penalties. 209.409 Section 209.409 Transportation... TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Reporting of Remedial Actions § 209.409 Penalties. Any...

Teratogenic responses of zebrafish embryos to decabromodiphenyl ether (BDE-209) in the presence of nano-SiO2 particles.

PubMed

Chao, Shu-Ju; Huang, Chin Pao; Chen, Pei-Chung; Huang, Chihpin

2017-07-01

This study investigated the influence of nano-SiO 2 particles (nSiO 2 ) on the teratogenic responses of zebrafish embryos to decabromodiphenyl ether (BDE-209). Zebrafish embryos were exposed to BDE-209 in the absence and presence of nSiO 2 for 96 h post fertilization (hpf). Results showed that formation of nSiO 2 -BDE-209 associates promoted both extracellular and intracellular uptake of BDE-209 by zebrafish embryos, thereby increasing the bioconcentration of BDE-209 on the chorion surface and the embryos. Results also showed embryos delay hatching temporarily when co-exposure to BDE-209 and nSiO 2 at 60 hpf. Furthermore, there was heartbeat decline (28.3 beats/10s) and increase in irregular heartbeat (45.8%) in zebrafish larvae at 96 hpf, compared to the sole exposure to BDE-209 (32.7 beats/10s and 0%). Malformation in terms of spinal curvature (SC), pericardial edema (PE) and yolk sac edema (YSE) were observed on zebrafish larvae at 33.9, 23.4, and 18%, respectively. Overall, abnormal development of zebrafish was apparent when co-exposure to BDE-209 and nSiO 2 . All relevant evidence considered, nSiO 2 could facilitate the transport of BDE-209 towards zebrafish embryos and negatively impact the development of zebrafish. Copyright © 2017 Elsevier Ltd. All rights reserved.

48 CFR 2452.209-70 - Potential organizational conflicts of interest.

Code of Federal Regulations, 2010 CFR

2010-10-01

... nature of the potential conflict of interest is [Contracting Officer insert description]: (c) Offerors... conflicts of interest. 2452.209-70 Section 2452.209-70 Federal Acquisition Regulations System DEPARTMENT OF... Provisions and Clauses 2452.209-70 Potential organizational conflicts of interest. As prescribed in 2409.507...

48 CFR 1352.209-70 - Potential organizational conflict of interest.

Code of Federal Regulations, 2010 CFR

2010-10-01

... and Consultant Conflicts of Interest) due to [state the nature of the potential conflict]. Accordingly... conflict of interest. 1352.209-70 Section 1352.209-70 Federal Acquisition Regulations System DEPARTMENT OF....209-70 Potential organizational conflict of interest. As prescribed in 48 CFR 1309.507-1(a), insert...

29 CFR 2200.209 - Hearing.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 9 2013-07-01 2013-07-01 false Hearing. 2200.209 Section 2200.209 Labor Regulations... Simplified Proceedings § 2200.209 Hearing. (a) Procedures. As soon as practicable after the conclusion of the pre-hearing conference, the Judge will hold a hearing on any issue that remains in dispute. The...

29 CFR 2200.209 - Hearing.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 9 2012-07-01 2012-07-01 false Hearing. 2200.209 Section 2200.209 Labor Regulations... Simplified Proceedings § 2200.209 Hearing. (a) Procedures. As soon as practicable after the conclusion of the pre-hearing conference, the Judge will hold a hearing on any issue that remains in dispute. The...

12 CFR 209.5 - The share register.

Code of Federal Regulations, 2010 CFR

2010-01-01

... CANCELLATION OF FEDERAL RESERVE BANK CAPITAL STOCK (REGULATION I) § 209.5 The share register. (a) Electronic or... cancellation dates and prices of shares cancelled, as the case may be. ... 12 Banks and Banking 2 2010-01-01 2010-01-01 false The share register. 209.5 Section 209.5 Banks...

20 CFR 209.4 - Method of filing.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Method of filing. 209.4 Section 209.4... EMPLOYERS' REPORTS AND RESPONSIBILITIES § 209.4 Method of filing. Any report or information required to be... with the Board electronically, which includes the use of magnetic tape, computer diskette, electronic...

18 CFR 376.209 - Procedures during periods of emergency requiring activation of the Continuity of Operations Plan.

Code of Federal Regulations, 2011 CFR

2011-04-01

... periods of emergency requiring activation of the Continuity of Operations Plan. 376.209 Section 376.209... GENERAL RULES ORGANIZATION, MISSION, AND FUNCTIONS; OPERATIONS DURING EMERGENCY CONDITIONS Commission Operation During Emergency Conditions § 376.209 Procedures during periods of emergency requiring activation...

40 CFR 761.209 - Number of copies of a manifest.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., AND USE PROHIBITIONS PCB Waste Disposal Records and Reports § 761.209 Number of copies of a manifest... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Number of copies of a manifest. 761.209 Section 761.209 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC...

40 CFR 761.209 - Number of copies of a manifest.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., AND USE PROHIBITIONS PCB Waste Disposal Records and Reports § 761.209 Number of copies of a manifest... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Number of copies of a manifest. 761.209 Section 761.209 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC...

29 CFR 2200.209 - Hearing.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false Hearing. 2200.209 Section 2200.209 Labor Regulations... Simplified Proceedings § 2200.209 Hearing. (a) Procedures. As soon as practicable after the conclusion of the pre-hearing conference, the Judge will hold a hearing on any issue that remains in dispute. The...

10 CFR 26.209 - Self-declarations.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 1 2013-01-01 2013-01-01 false Self-declarations. 26.209 Section 26.209 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Managing Fatigue § 26.209 Self-declarations. (a) If an individual is performing, or being assessed for, work under a waiver of one or more of the requirements...

10 CFR 26.209 - Self-declarations.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 1 2014-01-01 2014-01-01 false Self-declarations. 26.209 Section 26.209 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Managing Fatigue § 26.209 Self-declarations. (a) If an individual is performing, or being assessed for, work under a waiver of one or more of the requirements...

10 CFR 26.209 - Self-declarations.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 1 2012-01-01 2012-01-01 false Self-declarations. 26.209 Section 26.209 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Managing Fatigue § 26.209 Self-declarations. (a) If an individual is performing, or being assessed for, work under a waiver of one or more of the requirements...

10 CFR 835.209 - Concentrations of radioactive material in air.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Concentrations of radioactive material in air. 835.209 Section 835.209 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Standards for Internal and External Exposure § 835.209 Concentrations of radioactive material in air. (a) The derived air...

10 CFR 835.209 - Concentrations of radioactive material in air.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Concentrations of radioactive material in air. 835.209 Section 835.209 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Standards for Internal and External Exposure § 835.209 Concentrations of radioactive material in air. (a) The derived air...

10 CFR 835.209 - Concentrations of radioactive material in air.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Concentrations of radioactive material in air. 835.209 Section 835.209 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Standards for Internal and External Exposure § 835.209 Concentrations of radioactive material in air. (a) The derived air...

10 CFR 835.209 - Concentrations of radioactive material in air.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Concentrations of radioactive material in air. 835.209 Section 835.209 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Standards for Internal and External Exposure § 835.209 Concentrations of radioactive material in air. (a) The derived air...

46 CFR 13.209 - Eligibility: Cargo course.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 1 2012-10-01 2012-10-01 false Eligibility: Cargo course. 13.209 Section 13.209... TANKERMEN Requirements for âTankerman-PICâ Endorsement § 13.209 Eligibility: Cargo course. Each applicant for an original “Tankerman-PIC” endorsement shall present a certificate of completion from a course in...

46 CFR 13.209 - Eligibility: Cargo course.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 1 2013-10-01 2013-10-01 false Eligibility: Cargo course. 13.209 Section 13.209... TANKERMEN Requirements for âTankerman-PICâ Endorsement § 13.209 Eligibility: Cargo course. Each applicant for an original “Tankerman-PIC” endorsement shall present a certificate of completion from a course in...

46 CFR 13.209 - Eligibility: Cargo course.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false Eligibility: Cargo course. 13.209 Section 13.209... TANKERMEN Requirements for âTankerman-PICâ Endorsement § 13.209 Eligibility: Cargo course. Each applicant for an original “Tankerman-PIC” endorsement shall present a certificate of completion from a course in...

46 CFR 13.209 - Eligibility: Cargo course.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Eligibility: Cargo course. 13.209 Section 13.209... TANKERMEN Requirements for âTankerman-PICâ Endorsement § 13.209 Eligibility: Cargo course. Each applicant for an original “Tankerman-PIC” endorsement shall present a certificate of completion from a course in...

24 CFR 941.209 - Audit.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Audit. 941.209 Section 941.209... HOUSING DEVELOPMENT PHA Eligibility and Program Requirements § 941.209 Audit. All PHAs that receive funds under this part for the development of low-income housing shall comply with audit requirements in 24 CFR...

47 CFR 53.209 - Biennial audit.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 3 2010-10-01 2010-10-01 false Biennial audit. 53.209 Section 53.209... PROVISIONS CONCERNING BELL OPERATING COMPANIES Separate Affiliate; Safeguards § 53.209 Biennial audit. (a) A... obtain and pay for a Federal/State joint audit every two years conducted by an independent auditor to...

10 CFR 26.209 - Self-declarations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Self-declarations. 26.209 Section 26.209 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Managing Fatigue § 26.209 Self-declarations. (a) If an individual is performing, or being assessed for, work under a waiver of the requirements contained in § 26...

10 CFR 26.209 - Self-declarations.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 1 2011-01-01 2011-01-01 false Self-declarations. 26.209 Section 26.209 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Managing Fatigue § 26.209 Self-declarations. (a) If an individual is performing, or being assessed for, work under a waiver of the requirements contained in § 26...

7 CFR 20.9 - Records.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 1 2014-01-01 2014-01-01 false Records. 20.9 Section 20.9 Agriculture Office of the Secretary of Agriculture EXPORT SALES REPORTING REQUIREMENTS § 20.9 Records. Each reporting exporter shall establish and maintain accurate records as to all export sales of commodities subject to these regulations...

7 CFR 20.9 - Records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 1 2010-01-01 2010-01-01 false Records. 20.9 Section 20.9 Agriculture Office of the Secretary of Agriculture EXPORT SALES REPORTING REQUIREMENTS § 20.9 Records. Each reporting exporter shall establish and maintain accurate records as to all export sales of commodities subject to these regulations...

47 CFR 97.209 - Earth station.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 5 2013-10-01 2013-10-01 false Earth station. 97.209 Section 97.209... SERVICE Special Operations § 97.209 Earth station. (a) Any amateur station may be an Earth station. A holder of any class operator license may be the control operator of an Earth station, subject to the...

47 CFR 97.209 - Earth station.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 5 2011-10-01 2011-10-01 false Earth station. 97.209 Section 97.209... SERVICE Special Operations § 97.209 Earth station. (a) Any amateur station may be an Earth station. A holder of any class operator license may be the control operator of an Earth station, subject to the...

47 CFR 97.209 - Earth station.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 47 Telecommunication 5 2012-10-01 2012-10-01 false Earth station. 97.209 Section 97.209... SERVICE Special Operations § 97.209 Earth station. (a) Any amateur station may be an Earth station. A holder of any class operator license may be the control operator of an Earth station, subject to the...

47 CFR 97.209 - Earth station.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 5 2010-10-01 2010-10-01 false Earth station. 97.209 Section 97.209... SERVICE Special Operations § 97.209 Earth station. (a) Any amateur station may be an Earth station. A holder of any class operator license may be the control operator of an Earth station, subject to the...

47 CFR 97.209 - Earth station.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 5 2014-10-01 2014-10-01 false Earth station. 97.209 Section 97.209... SERVICE Special Operations § 97.209 Earth station. (a) Any amateur station may be an Earth station. A holder of any class operator license may be the control operator of an Earth station, subject to the...

48 CFR 2052.209-72 - Contractor organizational conflicts of interest.

Code of Federal Regulations, 2010 CFR

2010-10-01

... conflicts of interest. 2052.209-72 Section 2052.209-72 Federal Acquisition Regulations System NUCLEAR... Clauses 2052.209-72 Contractor organizational conflicts of interest. As prescribed at 2009.570-5(a) and..., contracts, and simplified acquisitions of the types described; 2009.570-4(b): Contractor Organizational...

5 CFR 179.209 - Voluntary repayment agreement as alternative to salary offset.

Code of Federal Regulations, 2010 CFR

2010-01-01

... alternative to salary offset. 179.209 Section 179.209 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS CLAIMS COLLECTION STANDARDS Salary Offset § 179.209 Voluntary repayment agreement as alternative to salary offset. (a)(1) In response to a notice of intent, an employee may propose...

40 CFR 180.209 - Terbacil; tolerances for residues.

Code of Federal Regulations, 2010 CFR

2010-07-01

....209 Section 180.209 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Specific Tolerances § 180.209..., hay 2.0 Apple 0.3 Asparagus 0.4 Blueberry 0.2 Caneberry subgroup 13A 0.2 Peach 0.2 Peppermint, tops 2...

40 CFR 180.209 - Terbacil; tolerances for residues.

Code of Federal Regulations, 2011 CFR

2011-07-01

....209 Section 180.209 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Specific Tolerances § 180.209..., hay 2.0 Apple 0.3 Asparagus 0.4 Blueberry 0.2 Caneberry subgroup 13A 0.2 Peach 0.2 Peppermint, tops 2...

7 CFR 3555.209 - Rural Energy Plus loans.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 15 2014-01-01 2014-01-01 false Rural Energy Plus loans. 3555.209 Section 3555.209... AGRICULTURE GUARANTEED RURAL HOUSING PROGRAM (Eff. 9-1-14) Underwriting the Property § 3555.209 Rural Energy Plus loans. Loans guaranteed under Rural Energy Plus provisions are for the purchase of energy...

48 CFR 1852.209-72 - Composition of the contractor.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contractor. 1852.209-72 Section 1852.209-72 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND... and Clauses 1852.209-72 Composition of the contractor. As prescribed in 1809.670, insert the following clause: Composition of the Contractor (DEC 1988) If the Contractor is comprised of more than one legal...

14 CFR 135.209 - VFR: Fuel supply.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false VFR: Fuel supply. 135.209 Section 135.209 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS... Limitations and Weather Requirements § 135.209 VFR: Fuel supply. (a) No person may begin a flight operation in...

14 CFR 135.209 - VFR: Fuel supply.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false VFR: Fuel supply. 135.209 Section 135.209 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS... Limitations and Weather Requirements § 135.209 VFR: Fuel supply. (a) No person may begin a flight operation in...

14 CFR 135.209 - VFR: Fuel supply.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false VFR: Fuel supply. 135.209 Section 135.209 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS... Limitations and Weather Requirements § 135.209 VFR: Fuel supply. (a) No person may begin a flight operation in...

14 CFR 135.209 - VFR: Fuel supply.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false VFR: Fuel supply. 135.209 Section 135.209 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS... Limitations and Weather Requirements § 135.209 VFR: Fuel supply. (a) No person may begin a flight operation in...

13 CFR 400.209 - Funding for the Program.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Funding for the Program. 400.209 Section 400.209 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.209 Funding for the Program. The Act provides funding for...

13 CFR 400.209 - Funding for the Program.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 13 Business Credit and Assistance 1 2012-01-01 2012-01-01 false Funding for the Program. 400.209 Section 400.209 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.209 Funding for the Program. The Act provides funding for...

13 CFR 400.209 - Funding for the Program.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false Funding for the Program. 400.209 Section 400.209 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.209 Funding for the Program. The Act provides funding for...

13 CFR 400.209 - Funding for the Program.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 13 Business Credit and Assistance 1 2014-01-01 2014-01-01 false Funding for the Program. 400.209 Section 400.209 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.209 Funding for the Program. The Act provides funding for...

13 CFR 400.209 - Funding for the Program.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false Funding for the Program. 400.209 Section 400.209 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.209 Funding for the Program. The Act provides funding for...

Therapeutic Role of Bmi-1 Inhibitors in Eliminating Prostate Tumor Stem Cells

DTIC Science & Technology

2015-10-01

antitumor activity in mouse xenografts did not exert toxic effects on normal tissues. BMI-1 targeted therapy when combined with taxotere resulted in...utilizing zebrafish xenografts (Sabaawy Lab) and prostate cancer cell lines (Bertino Lab), and 3) Confirmation of the antitumor activity of C-209...in mouse xenografts alone and upon combination with taxotere (Bertino Lab). The following tasks from the approved SOW were performed to achieve the

Hubble Sweeps a Messy Star Factory

NASA Image and Video Library

2017-12-08

This sprinkle of cosmic glitter is a blue compact dwarf galaxy known as Markarian 209. Galaxies of this type are blue-hued, compact in size, gas-rich, and low in heavy elements. They are often used by astronomers to study star formation, as their conditions are similar to those thought to exist in the early Universe. Markarian 209 in particular has been studied extensively. It is filled with diffuse gas and peppered with star-forming regions towards its core. This image captures it undergoing a particularly dramatic burst of star formation, visible as the lighter blue cloudy region towards the top right of the galaxy. This clump is filled with very young and hot newborn stars. This galaxy was initially thought to be a young galaxy undergoing its very first episode of star formation, but later research showed that Markarian 209 is actually very old, with an almost continuous history of forming new stars. It is thought to have never had a dormant period — a period during which no stars were formed — lasting longer than 100 million years. The dominant population of stars in Markarian 209 is still quite young, in stellar terms, with ages of under 3 million years. For comparison, the sun is some 4.6 billion years old, and is roughly halfway through its expected lifespan. The observations used to make this image were taken using Hubble’s Wide Field Camera 3 and Advanced Camera for Surveys, and span the ultraviolet, visible, and infrared parts of the spectrum. A scattering of other bright galaxies can be seen across the frame, including the bright golden oval that could, due to a trick of perspective, be mistaken as part of Markarian 209 but is in fact a background galaxy. Credit: ESA/Hubble & NASA Acknowledgement: Nick Rose NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Development of Effective Aerobic Cometabolic Systems for the In Situ Transformation of Problematic Chlorinated Solvent Mixtures

DTIC Science & Technology

2005-02-01

vector contained the ampicillin resistance gene , only transformed colonies should grow on the plates and since the inserted DNA should have knocked...flava 340 209 203 69 2422 Nitrogen-fixing bacterium MI753 340 209 203 69 2571 Pseudomonas spinosa 340 209 203 217 2458 Xylophilus ampelinus 340 209...277 203 198 2767 Unidentified bacterium 340 277 203 198 2674 Type 0803 filamentous bacterium 340 277 203 198 2581 Xylophilus ampelinus 340 209 203 217

12 CFR 209.3 - Cancellation of Reserve Bank stock.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Cancellation of Reserve Bank stock. 209.3 Section 209.3 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM ISSUE AND CANCELLATION OF FEDERAL RESERVE BANK CAPITAL STOCK (REGULATION I) § 209.3 Cancellation of...

12 CFR 209.3 - Cancellation of Reserve Bank stock.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 2 2011-01-01 2011-01-01 false Cancellation of Reserve Bank stock. 209.3 Section 209.3 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM ISSUE AND CANCELLATION OF FEDERAL RESERVE BANK CAPITAL STOCK (REGULATION I) § 209.3 Cancellation of...

40 CFR 94.209 - Special provisions for post-manufacture marinizers and small-volume manufacturers.

Code of Federal Regulations, 2010 CFR

2010-07-01

...-manufacture marinizers and small-volume manufacturers. 94.209 Section 94.209 Protection of Environment... COMPRESSION-IGNITION ENGINES Certification Provisions § 94.209 Special provisions for post-manufacture... demonstrate one of the following: (1) It is a post-manufacture marinizer and that the base engines used for...

41 CFR 101-27.209-1 - GSA stock items.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true GSA stock items. 101-27.209-1 Section 101-27.209-1 Public Contracts and Property Management Federal Property Management...-Management of Shelf-Life Materials § 101-27.209-1 GSA stock items. Shelf-life items that meet the criteria...

27 CFR 9.209 - Calistoga.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Calistoga. 9.209 Section 9.209 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL AMERICAN VITICULTURAL AREAS Approved American Viticultural Areas § 9.209 Calistoga. (a) Name. The name of the viticultural area...

27 CFR 9.209 - Calistoga.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Calistoga. 9.209 Section 9.209 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS AMERICAN VITICULTURAL AREAS Approved American Viticultural Areas § 9.209 Calistoga. (a) Name. The name of the viticultural area...

27 CFR 9.209 - Calistoga.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Calistoga. 9.209 Section 9.209 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS AMERICAN VITICULTURAL AREAS Approved American Viticultural Areas § 9.209 Calistoga. (a) Name. The name of the viticultural area...

27 CFR 9.209 - Calistoga.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Calistoga. 9.209 Section 9.209 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS AMERICAN VITICULTURAL AREAS Approved American Viticultural Areas § 9.209 Calistoga. (a) Name. The name of the viticultural area...

27 CFR 9.209 - Calistoga.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Calistoga. 9.209 Section 9.209 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL AMERICAN VITICULTURAL AREAS Approved American Viticultural Areas § 9.209 Calistoga. (a) Name. The name of the viticultural area...

8 CFR 209.2 - Adjustment of status of alien granted asylum.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Adjustment of status of alien granted asylum. 209.2 Section 209.2 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS OF REFUGEES AND ALIENS GRANTED ASYLUM § 209.2 Adjustment of status of alien...

8 CFR 209.2 - Adjustment of status of alien granted asylum.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Adjustment of status of alien granted asylum. 209.2 Section 209.2 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS OF REFUGEES AND ALIENS GRANTED ASYLUM § 209.2 Adjustment of status of alien...

8 CFR 209.2 - Adjustment of status of alien granted asylum.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Adjustment of status of alien granted asylum. 209.2 Section 209.2 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS OF REFUGEES AND ALIENS GRANTED ASYLUM § 209.2 Adjustment of status of alien...

8 CFR 209.2 - Adjustment of status of alien granted asylum.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Adjustment of status of alien granted asylum. 209.2 Section 209.2 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS OF REFUGEES AND ALIENS GRANTED ASYLUM § 209.2 Adjustment of status of alien...

8 CFR 209.2 - Adjustment of status of alien granted asylum.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Adjustment of status of alien granted asylum. 209.2 Section 209.2 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS OF REFUGEES AND ALIENS GRANTED ASYLUM § 209.2 Adjustment of status of alien...

30 CFR 20.9 - Class 2 lamps.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Class 2 lamps. 20.9 Section 20.9 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MINE LAMPS OTHER THAN STANDARD CAP LAMPS § 20.9 Class 2 lamps. (a) Safety. (1...

48 CFR 1352.209-75 - Title 13 and non-disclosure requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

....209-75 Title 13 and non-disclosure requirements. As prescribed in 48 CFR 1309.507-2(e), insert the following clause: Title 13 and Non-Disclosure Requirements (APR 2010) The Census Bureau's data are protected...-disclosure requirements. 1352.209-75 Section 1352.209-75 Federal Acquisition Regulations System DEPARTMENT OF...

12 CFR 209.5 - The share register.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 2 2011-01-01 2011-01-01 false The share register. 209.5 Section 209.5 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM ISSUE AND CANCELLATION OF FEDERAL RESERVE BANK CAPITAL STOCK (REGULATION I) § 209.5 The share register. (a) Electronic or...

49 CFR 382.209 - Use following an accident.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 5 2010-10-01 2010-10-01 false Use following an accident. 382.209 Section 382.209... ALCOHOL USE AND TESTING Prohibitions § 382.209 Use following an accident. No driver required to take a post-accident alcohol test under § 382.303 shall use alcohol for eight hours following the accident, or...

49 CFR 382.209 - Use following an accident.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 5 2011-10-01 2011-10-01 false Use following an accident. 382.209 Section 382.209... ALCOHOL USE AND TESTING Prohibitions § 382.209 Use following an accident. No driver required to take a post-accident alcohol test under § 382.303 shall use alcohol for eight hours following the accident, or...

29 CFR 825.209 - Maintenance of employee benefits.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 3 2012-07-01 2012-07-01 false Maintenance of employee benefits. 825.209 Section 825.209... Leave Act § 825.209 Maintenance of employee benefits. (a) During any FMLA leave, an employer must... benefits provided to an employee prior to taking FMLA leave must be maintained during the FMLA leave. For...

29 CFR 825.209 - Maintenance of employee benefits.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 3 2013-07-01 2013-07-01 false Maintenance of employee benefits. 825.209 Section 825.209... Leave Act § 825.209 Maintenance of employee benefits. (a) During any FMLA leave, an employer must... benefits provided to an employee prior to taking FMLA leave must be maintained during the FMLA leave. For...

40 CFR 209.22 - Other discovery.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Other discovery. 209.22 Section 209.22... Orders Issued Under Section 11(d) of the Noise Control Act § 209.22 Other discovery. (a) Further discovery under this section shall be undertaken only upon order of the administrative law judge or upon...

40 CFR 209.22 - Other discovery.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Other discovery. 209.22 Section 209.22... Orders Issued Under Section 11(d) of the Noise Control Act § 209.22 Other discovery. (a) Further discovery under this section shall be undertaken only upon order of the administrative law judge or upon...

40 CFR 209.22 - Other discovery.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Other discovery. 209.22 Section 209.22... Orders Issued Under Section 11(d) of the Noise Control Act § 209.22 Other discovery. (a) Further discovery under this section shall be undertaken only upon order of the administrative law judge or upon...

14 CFR 135.209 - VFR: Fuel supply.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false VFR: Fuel supply. 135.209 Section 135.209... AND ON DEMAND OPERATIONS AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT VFR/IFR Operating Limitations and Weather Requirements § 135.209 VFR: Fuel supply. (a) No person may begin a flight operation in...

46 CFR 108.209 - Hospital spaces.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Hospital spaces. 108.209 Section 108.209 Shipping COAST... Construction and Arrangement Accommodation Spaces § 108.209 Hospital spaces. (a) Each unit carrying twelve or more persons on a voyage of more than three days must have a hospital space. (b) Each hospital space...

46 CFR 108.209 - Hospital spaces.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Hospital spaces. 108.209 Section 108.209 Shipping COAST... Construction and Arrangement Accommodation Spaces § 108.209 Hospital spaces. (a) Each unit carrying twelve or more persons on a voyage of more than three days must have a hospital space. (b) Each hospital space...

46 CFR 108.209 - Hospital spaces.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Hospital spaces. 108.209 Section 108.209 Shipping COAST... Construction and Arrangement Accommodation Spaces § 108.209 Hospital spaces. (a) Each unit carrying twelve or more persons on a voyage of more than three days must have a hospital space. (b) Each hospital space...

46 CFR 108.209 - Hospital spaces.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Hospital spaces. 108.209 Section 108.209 Shipping COAST... Construction and Arrangement Accommodation Spaces § 108.209 Hospital spaces. (a) Each unit carrying twelve or more persons on a voyage of more than three days must have a hospital space. (b) Each hospital space...

46 CFR 108.209 - Hospital spaces.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Hospital spaces. 108.209 Section 108.209 Shipping COAST... Construction and Arrangement Accommodation Spaces § 108.209 Hospital spaces. (a) Each unit carrying twelve or more persons on a voyage of more than three days must have a hospital space. (b) Each hospital space...

10 CFR 590.209 - Exchanges by displacement.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Exchanges by displacement. 590.209 Section 590.209 Energy... Natural Gas § 590.209 Exchanges by displacement. Any importer of natural gas may enter into an exchange by displacement agreement without the prior authorization of the Assistant Secretary when the net effect of the...

10 CFR 590.209 - Exchanges by displacement.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Exchanges by displacement. 590.209 Section 590.209 Energy... Natural Gas § 590.209 Exchanges by displacement. Any importer of natural gas may enter into an exchange by displacement agreement without the prior authorization of the Assistant Secretary when the net effect of the...

10 CFR 590.209 - Exchanges by displacement.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Exchanges by displacement. 590.209 Section 590.209 Energy... Natural Gas § 590.209 Exchanges by displacement. Any importer of natural gas may enter into an exchange by displacement agreement without the prior authorization of the Assistant Secretary when the net effect of the...

10 CFR 590.209 - Exchanges by displacement.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Exchanges by displacement. 590.209 Section 590.209 Energy... Natural Gas § 590.209 Exchanges by displacement. Any importer of natural gas may enter into an exchange by displacement agreement without the prior authorization of the Assistant Secretary when the net effect of the...

10 CFR 590.209 - Exchanges by displacement.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Exchanges by displacement. 590.209 Section 590.209 Energy... Natural Gas § 590.209 Exchanges by displacement. Any importer of natural gas may enter into an exchange by displacement agreement without the prior authorization of the Assistant Secretary when the net effect of the...

40 CFR 209.22 - Other discovery.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Other discovery. 209.22 Section 209.22... Orders Issued Under Section 11(d) of the Noise Control Act § 209.22 Other discovery. (a) Further discovery under this section shall be undertaken only upon order of the administrative law judge or upon...

40 CFR 209.12 - Time.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Time. 209.12 Section 209.12 Protection... Issued Under Section 11(d) of the Noise Control Act § 209.12 Time. (a) In computing any period of time... period of time begins to run shall not be included, except as otherwise provided. Saturdays, Sundays, and...

40 CFR 209.12 - Time.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Time. 209.12 Section 209.12 Protection... Issued Under Section 11(d) of the Noise Control Act § 209.12 Time. (a) In computing any period of time... period of time begins to run shall not be included, except as otherwise provided. Saturdays, Sundays, and...

40 CFR 209.12 - Time.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Time. 209.12 Section 209.12 Protection... Issued Under Section 11(d) of the Noise Control Act § 209.12 Time. (a) In computing any period of time... period of time begins to run shall not be included, except as otherwise provided. Saturdays, Sundays, and...

40 CFR 209.12 - Time.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Time. 209.12 Section 209.12 Protection... Issued Under Section 11(d) of the Noise Control Act § 209.12 Time. (a) In computing any period of time... period of time begins to run shall not be included, except as otherwise provided. Saturdays, Sundays, and...

40 CFR 209.12 - Time.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Time. 209.12 Section 209.12 Protection... Issued Under Section 11(d) of the Noise Control Act § 209.12 Time. (a) In computing any period of time... period of time begins to run shall not be included, except as otherwise provided. Saturdays, Sundays, and...

40 CFR 209.28 - Record.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Record. 209.28 Section 209.28... Orders Issued Under Section 11(d) of the Noise Control Act § 209.28 Record. (a) Hearings shall be... of the record and the sole official transcript. Copies of the record shall be filed with the hearing...

40 CFR 209.28 - Record.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Record. 209.28 Section 209.28... Orders Issued Under Section 11(d) of the Noise Control Act § 209.28 Record. (a) Hearings shall be... of the record and the sole official transcript. Copies of the record shall be filed with the hearing...

40 CFR 209.28 - Record.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Record. 209.28 Section 209.28... Orders Issued Under Section 11(d) of the Noise Control Act § 209.28 Record. (a) Hearings shall be... of the record and the sole official transcript. Copies of the record shall be filed with the hearing...

49 CFR 219.209 - Reports of tests and refusals.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Reports of tests and refusals. 219.209 Section 219.209 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CONTROL OF ALCOHOL AND DRUG USE Post-Accident Toxicological Testing § 219.209 Reports of tests and refusals. (...

48 CFR 1852.209-70 - Product removal from Qualified Products List.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Product removal from Qualified Products List. 1852.209-70 Section 1852.209-70 Federal Acquisition Regulations System NATIONAL... Provisions and Clauses 1852.209-70 Product removal from Qualified Products List. As prescribed in 1809.206-71...

48 CFR 1553.209-71 - EPA Form 1900-27, Project Officer's Evaluation of Contractor Performance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Officer's Evaluation of Contractor Performance. 1553.209-71 Section 1553.209-71 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY CLAUSES AND FORMS FORMS Prescription of Forms 1553.209-71 EPA Form 1900-27, Project Officer's Evaluation of Contractor Performance. As prescribed in 1509.170-4...

14 CFR 91.209 - Aircraft lights.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Aircraft lights. 91.209 Section 91.209... Requirements § 91.209 Aircraft lights. No person may: (a) During the period from sunset to sunrise (or, in... position lights; (2) Park or move an aircraft in, or in dangerous proximity to, a night flight operations...

14 CFR 91.209 - Aircraft lights.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Aircraft lights. 91.209 Section 91.209... Requirements § 91.209 Aircraft lights. No person may: (a) During the period from sunset to sunrise (or, in... position lights; (2) Park or move an aircraft in, or in dangerous proximity to, a night flight operations...

14 CFR 91.209 - Aircraft lights.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Aircraft lights. 91.209 Section 91.209... Requirements § 91.209 Aircraft lights. No person may: (a) During the period from sunset to sunrise (or, in... position lights; (2) Park or move an aircraft in, or in dangerous proximity to, a night flight operations...

14 CFR 91.209 - Aircraft lights.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Aircraft lights. 91.209 Section 91.209... Requirements § 91.209 Aircraft lights. No person may: (a) During the period from sunset to sunrise (or, in... position lights; (2) Park or move an aircraft in, or in dangerous proximity to, a night flight operations...

14 CFR 91.209 - Aircraft lights.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Aircraft lights. 91.209 Section 91.209... Requirements § 91.209 Aircraft lights. No person may: (a) During the period from sunset to sunrise (or, in... position lights; (2) Park or move an aircraft in, or in dangerous proximity to, a night flight operations...

12 CFR 209.2 - Banks desiring to become member banks.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 2 2011-01-01 2011-01-01 false Banks desiring to become member banks. 209.2 Section 209.2 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM ISSUE AND CANCELLATION OF FEDERAL RESERVE BANK CAPITAL STOCK (REGULATION I) § 209.2 Banks desiring to...

46 CFR 502.209 - Use of depositions at hearings.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 9 2011-10-01 2011-10-01 false Use of depositions at hearings. 502.209 Section 502.209... Depositions, Written Interrogatories, and Discovery § 502.209 Use of depositions at hearings. (a) General. At the hearing, any part or all of a deposition, so far as admissible under the rules of evidence, may be...

46 CFR 502.209 - Use of depositions at hearings.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 9 2010-10-01 2010-10-01 false Use of depositions at hearings. 502.209 Section 502.209... Depositions, Written Interrogatories, and Discovery § 502.209 Use of depositions at hearings. (a) General. At the hearing, any part or all of a deposition, so far as admissible under the rules of evidence, may be...

29 CFR 778.209 - Method of inclusion of bonus in regular rate.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 3 2012-07-01 2012-07-01 false Method of inclusion of bonus in regular rate. 778.209 Section 778.209 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF... COMPENSATION Payments That May Be Excluded From the âRegular Rateâ Bonuses § 778.209 Method of inclusion of...

29 CFR 778.209 - Method of inclusion of bonus in regular rate.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 3 2013-07-01 2013-07-01 false Method of inclusion of bonus in regular rate. 778.209 Section 778.209 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF... COMPENSATION Payments That May Be Excluded From the âRegular Rateâ Bonuses § 778.209 Method of inclusion of...

29 CFR 778.209 - Method of inclusion of bonus in regular rate.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 3 2014-07-01 2014-07-01 false Method of inclusion of bonus in regular rate. 778.209 Section 778.209 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF... COMPENSATION Payments That May Be Excluded From the âRegular Rateâ Bonuses § 778.209 Method of inclusion of...

29 CFR 778.209 - Method of inclusion of bonus in regular rate.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Method of inclusion of bonus in regular rate. 778.209 Section 778.209 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF... COMPENSATION Payments That May Be Excluded From the âRegular Rateâ Bonuses § 778.209 Method of inclusion of...

41 CFR 101-27.209 - Utilization and distribution of shelf-life items.

Code of Federal Regulations, 2014 CFR

2014-07-01

... distribution of shelf-life items. 101-27.209 Section 101-27.209 Public Contracts and Property Management... PROCUREMENT 27-INVENTORY MANAGEMENT 27.2-Management of Shelf-Life Materials § 101-27.209 Utilization and distribution of shelf-life items. Where it is determined that specified quantities of both Type I and Type II...

29 CFR 778.209 - Method of inclusion of bonus in regular rate.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 3 2011-07-01 2011-07-01 false Method of inclusion of bonus in regular rate. 778.209 Section 778.209 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF... COMPENSATION Payments That May Be Excluded From the âRegular Rateâ Bonuses § 778.209 Method of inclusion of...

30 CFR 77.209 - Surge and storage piles.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Surge and storage piles. 77.209 Section 77.209... Installations § 77.209 Surge and storage piles. No person shall be permitted to walk or stand immediately above a reclaiming area or in any other area at or near a surge or storage pile where the reclaiming...

30 CFR 77.209 - Surge and storage piles.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Surge and storage piles. 77.209 Section 77.209... Installations § 77.209 Surge and storage piles. No person shall be permitted to walk or stand immediately above a reclaiming area or in any other area at or near a surge or storage pile where the reclaiming...

42 CFR 59.209 - Civil rights.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Civil rights. 59.209 Section 59.209 Public Health... Grants for Family Planning Service Training § 59.209 Civil rights. Attention is called to the requirements of Title VI of the Civil Rights Act of 1964 (78 Stat. 252, 42 U.S.C. 2000d et seq.) and in...

42 CFR 59.209 - Civil rights.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Civil rights. 59.209 Section 59.209 Public Health... Grants for Family Planning Service Training § 59.209 Civil rights. Attention is called to the requirements of Title VI of the Civil Rights Act of 1964 (78 Stat. 252, 42 U.S.C. 2000d et seq.) and in...

42 CFR 59.209 - Civil rights.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Civil rights. 59.209 Section 59.209 Public Health... Grants for Family Planning Service Training § 59.209 Civil rights. Attention is called to the requirements of Title VI of the Civil Rights Act of 1964 (78 Stat. 252, 42 U.S.C. 2000d et seq.) and in...

42 CFR 59.209 - Civil rights.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Civil rights. 59.209 Section 59.209 Public Health... Grants for Family Planning Service Training § 59.209 Civil rights. Attention is called to the requirements of Title VI of the Civil Rights Act of 1964 (78 Stat. 252, 42 U.S.C. 2000d et seq.) and in...

42 CFR 59.209 - Civil rights.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Civil rights. 59.209 Section 59.209 Public Health... Grants for Family Planning Service Training § 59.209 Civil rights. Attention is called to the requirements of Title VI of the Civil Rights Act of 1964 (78 Stat. 252, 42 U.S.C. 2000d et seq.) and in...

Erratum: ``On the Evolution of Star-forming Galaxies'' (ApJ, 615, 209 [2004])

NASA Astrophysics Data System (ADS)

Hopkins, A. M.

2007-01-01

The star formation rate (SFR) density values reported in my 2004 paper for the data taken from D. W. Hogg et al. (ApJ, 615, 209 [2004]) are in error. The original cosmology conversion factor used was incorrect, and the values listed in Table 2 for both C1 and ρ˙*com are in error. Moreover, the (incorrect) value reported for C1 was not that used in calculating the (incorrect) values of ρ˙*com. The correct cosmology conversion leads to SFR density values that are smaller than those given in the original paper by amounts decreasing monotonically from ~43% for the z=0.2 bin to ~30% for the z=1.2 bin, as indicated by A. M. Hopkins & J. F. Beacom (ApJ, 615, 209 [2004]), who show an updated version of the star formation history diagram (compare their Fig. 1 with my original Fig. 1). The correct SFR density values are given here in a new Table 1, which has the same format as Table 2 of my original paper, although the table notes are omitted here. Apart from the location of the corresponding data points in Figure 1, this error does not significantly alter any of the results or conclusions of the original paper. I thank Chun Ly for bringing this error to my attention.

Adrenergic antagonists restrict replication of Legionella.

PubMed

Harrison, Christopher F; Kicka, Sébastien; Kranjc, Agata; Finsel, Ivo; Chiriano, Gianpaolo; Ouertatani-Sakouhi, Hajer; Soldati, Thierry; Scapozza, Leonardo; Hilbi, Hubert

2015-07-01

Legionella pneumophila is a facultative intracellular bacterium, which upon inhalation can cause a potentially fatal pneumonia termed Legionnaires' disease. The opportunistic pathogen grows in environmental amoebae and mammalian macrophages within a unique membrane-bound compartment, the 'Legionella-containing vacuole'. Bacteria are exposed to many environmental cues including small signalling molecules from eukaryotic cells. A number of pathogenic bacteria sense and respond to catecholamine hormones, such as adrenalin and noradrenalin, a process mediated via the QseBC two-component system in some bacteria. In this study, we examined the effect of adrenergic compounds on L. pneumophila, and discovered that the adrenergic receptor antagonists benoxathian, naftopidil, propranolol and labetalol, as well as the QseC sensor kinase inhibitor LED209, reduced the growth of L. pneumophila in broth or amoebae, while replication in macrophages was enhanced. Growth restriction was common to members of the genus Legionella and Mycobacterium, and was observed for L. pneumophila in the replicative but not stationary phase of the biphasic life cycle. Deletion of the L. pneumophila qseBC genes indicated that growth inhibition by adrenergics or LED209 is mediated only to a minor extent by this two-component system, implying the presence of other adrenergic sensing systems. This study identifies adrenergic molecules as novel inhibitors of extra- and intracellular growth of Legionella and reveals LED209 as a potential lead compound to combat infections with Legionella or Mycobacterium spp.

18Ne Excited States Two-Proton Decay

NASA Astrophysics Data System (ADS)

de Napoli, M.; Rapisarda, E.; Raciti, G.; Cardella, G.; Amorini, F.; Giacoppo, F.; Sfienti, C.

2008-04-01

Two-proton radioactivity studies have been performed on excited states of 18Ne produced by 20Ne fragmentation at the FRS of the Laboratori Nazionali del Sud and excited via Coulomb excitation on a 209Pb target. The 18Ne levels decay has been studied by complete kinematical reconstruction. In spite of the low statistic, the energy and angular correlations of the emitted proton pairs indicate the presence of 2He emission toghether with the democratic decay.

Excitation of cavitation bubbles in low-temperature liquid nitrogen

NASA Astrophysics Data System (ADS)

Sasaki, Koichi; Harada, Shingo

2017-06-01

We excited a cavitation bubble by irradiating a Nd:YAG laser pulse onto a titanium target that was installed in liquid nitrogen at a temperature below the boiling point. To our knowledge, this is the first experiment in which a cavitation bubble has been successfully excited in liquid nitrogen. We compared the cavitation bubble in liquid nitrogen with that in water on the basis of an equation reported by Florschuetz and Chao [J. Heat Transfer 87, 209 (1965)].

Formation of polybrominated dibenzofurans (PBDFs) after heating of a salmon sample spiked with decabromodiphenyl ether (BDE-209).

PubMed

Vetter, Walter; Bendig, Paul; Blumenstein, Marina; Hägele, Florian; Behnisch, Peter A; Brouwer, Abraham

2015-10-01

Fish is a major source for the intake of polybrominated diphenyl ethers (PBDEs). However, fish is scarcely consumed without being cooked, and previous studies showed that the heating of salmon fillet contaminated with BDE-209 for longer periods of time was accompanied with the partial transformation of this brominated flame retardant. In this study, we heated salmon fillet spiked with BDE-209 and verified that this process was linked with the formation of polybrominated dibenzofurans (PBDFs) in the fish. Each minute of heating 1 g salmon fillet spiked with 200 ng BDE-209 generated about 0.5 ‰ PBDFs relative to the initial amount of the pre-dioxin BDE-209. This result of the chemical analysis by gas chromatography with mass spectrometry (GC/MS) was verified by means of an effect-directed bio-assay (DR CALUX). While unheated salmon with BDE-209 and heated salmon without BDE-209 were tested nontoxic, the bioanalytical response of fish linearly increased upon heating. We also found that PBDF formation did neither occur with BDE-47 nor when BDE-209 was heated in edible oil instead of salmon fillet. Due to the formation of PBDFs in this process, the consumption of heated, BDE-209 contaminated fish may add to the uptake of dioxin-like compounds with our diet.

The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cells

PubMed Central

Mayr, Christian; Wagner, Andrej; Loeffelberger, Magdalena; Bruckner, Daniela; Jakab, Martin; Berr, Frieder; Di Fazio, Pietro; Ocker, Matthias; Neureiter, Daniel; Pichler, Martin; Kiesslich, Tobias

2016-01-01

BMI1 is a core component of the polycomb repressive complex 1 (PRC1) and is up-regulated in biliary tract cancer (BTC), contributing to aggressive clinical features. In this study we investigated the cytotoxic effects of PTC-209, a recently developed inhibitor of BMI1, in BTC cells. PTC-209 reduced overall viability in BTC cell lines in a dose-dependent fashion (0.04 - 20 μM). Treatment with PTC-209 led to slightly enhanced caspase activity and stop of cell proliferation. Cell cycle analysis revealed that PTC-209 caused cell cycle arrest at the G1/S checkpoint. A comprehensive investigation of expression changes of cell cycle-related genes showed that PTC-209 caused significant down-regulation of cell cycle-promoting genes as well as of genes that contribute to DNA synthesis initiation and DNA repair, respectively. This was accompanied by significantly elevated mRNA levels of cell cycle inhibitors. In addition, PTC-209 reduced sphere formation and, in a cell line-dependent manner, aldehyde dehydrogease-1 positive cells. We conclude that PTC-209 might be a promising drug for future in vitro and in vivo studies in BTC. PMID:26623561

VizieR Online Data Catalog: Spatial structure of young stellar clusters. III. (Kuhn+, 2015)

NASA Astrophysics Data System (ADS)

Kuhn, M. A.; Feigelson, E. D.; Getman, K. V.; Sills, A.; Bate, M. R.; Borissova, J.

2017-10-01

This paper uses the Paper I (Kuhn et al. 2014, J/ApJ/787/107) catalog of 142 subclusters of young stars in 17 MYStIX star-forming regions. These subclusters were found and characterized using the stars in the MYStIX Probable Complex Member (MPCM) catalogs from Broos et al. (2013, J/ApJS/209/32). The multiwavelength data analysis efforts that went into this catalog are described by Feigelson et al. (2013, J/ApJS/209/26), King et al. (2013, J/ApJS/209/28), Kuhn et al. (2013, J/ApJS/209/27; 2013, J/ApJS/209/29), Naylor et al. (2013, J/ApJS/209/30), Povich et al. (2013, J/ApJS/209/31), and Townsley et al. (2014, J/ApJS/213/1), which provided uniform data coverage across the 17 star-forming regions investigated here, including the most comprehensive and reliable lists of young stars in many of the nearest MSFRs. (3 data files).

Lead effects on body composition and organ size of wintering canvasbacks Aythya valisineria in Louisiana

USGS Publications Warehouse

Pace, R.M.; Hohman, W.L.; Custer, T.W.

1999-01-01

We tested whether lead exposure, as evidenced by liver lead concentration, affected body composition and organ sizes of canvasback ducks Aythya valisineria in Louisiana during winter 1987-88. After adjusting for body size, sex, age, and site and month of collection, we found decreases in ingesta-free body mass; breast, leg, and body protein; body fat; intestine length; and liver and gizzard masses associated with increased liver lead concentrations. There were no apparent associations between liver lead concentrations and testes and body ash masses, or caecal length. We used the concentration of 26.7 ppm of liver lead on a dry matter (dm) basis as indicative of lead toxicosis. We predicted that a canvasback with 26.7 ppm dm liver lead would weigh 209 g less and have 105 g less fat than an unexposed individual. Whereas many lead exposed canvasbacks may survive through winter, their subsequent survival, ability to reproduce and perform other annual cycle events may be compromised. We recommend management to make lead unavailable to waterfowl at major concentration areas and periodic monitoring of lead contamination in waterfowl populations.

25 CFR 20.209 - Can a tribe operating under a tribal redesign plan go back to operating under this part?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 1 2012-04-01 2011-04-01 true Can a tribe operating under a tribal redesign plan go back to operating under this part? 20.209 Section 20.209 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Welfare Reform § 20.209...

Serine 209 resides within a putative p38(MAPK) consensus motif and regulates monoamine oxidase-A activity.

PubMed

Cao, Xia; Rui, Lewei; Pennington, Paul R; Chlan-Fourney, Jennifer; Jiang, Zhongjian; Wei, Zelan; Li, Xin-Min; Edmondson, Dale E; Mousseau, Darrell D

2009-10-01

The p38 mitogen-activated protein kinase (MAPK) cascade as well as the enzyme monoamine oxidase-A (MAO-A) have both been associated with oxidative stress. We observed that the specific inhibition of the p38(MAPK) protein [using either a chemical inhibitor or a dominant-negative p38(MAPK) clone] selectively induces MAO-A activity and MAO-A-sensitive toxicity in several neuronal cell lines, including primary cortical neurons. Over-expression of a constitutively active p38(MAPK) results in the phosphorylation of the MAO-A protein and inhibition of MAO-A activity. The MAO-A(Ser209Glu) phosphomimic - bearing a targeted substitution within a putative p38(MAPK) consensus motif - is neither active nor neurotoxic. In contrast, the MAO-A(Ser209Ala) variant (mimics dephosphorylation) does not associate with p38(MAPK), and is both very active and very toxic. Substitution of the homologous serine in the MAO-B isoform, i.e. Ser200, with either Glu or Ala does not affect the catalytic activity of the corresponding over-expressed proteins. These combined in vitro data strongly suggest a direct p38(MAPK)-dependent inhibition of MAO-A function. Based on published observations, this endogenous means of selectively regulating MAO-A function could provide for an adaptive response to oxidative stress associated with disorders as diverse as depression, reperfusion/ischemia, and the early stages of Alzheimer's disease.

49 CFR 40.209 - What procedural problems do not result in the cancellation of a test and do not require correction?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 1 2013-10-01 2013-10-01 false What procedural problems do not result in the cancellation of a test and do not require correction? 40.209 Section 40.209 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Problems in Drug Tests § 40.209 What procedura...

GNAQ and GNA11 mutations occur in 9.5% of mucosal melanoma and are associated with poor prognosis.

PubMed

Sheng, Xinan; Kong, Yan; Li, Yiqian; Zhang, Qiannan; Si, Lu; Cui, Chuanliang; Chi, Zhihong; Tang, Bixia; Mao, Lili; Lian, Bin; Wang, Xuan; Yan, Xieqiao; Li, Siming; Dai, Jie; Guo, Jun

2016-09-01

Mucosal melanoma (MM) is a rare subtype of melanoma in Caucasians with extremely poor prognosis, and therapy strategy has not been clearly established for MM. We aimed to investigate the genetic aberrations possibly applicable in targeted therapy of MM. We examined the somatic mutations of GNAQ and GNA11 (GNAQ/11, encoding the guanine nucleotide-binding alpha subunits) in MM and evaluated their correlation to clinicopathologic features of MM. This study collected samples from primary lesions of 284 MM patients. Tissue samples were analysed for mutations in exons 4 and 5 of GNAQ/11 in genomic DNA by polymerase chain reaction amplification and Sanger sequencing. Correlations of GNAQ/11 mutations to clinicopathologic features and prognosis of MM were evaluated. The overall mutation frequency of GNAQ/11 in MM was 9.5% (27 in 284), with a frequency of 4.6% and 4.9% for GNAQ and GNA11 mutations, respectively. The mutations in exon 5 of GNAQ/11 occurred exclusively in codon 209. GNAQ(Q209L) was the most prevalent variation (92.3% of missense GNAQ mutations). GNAQ/11 mutations were not significantly associated with age, gender, ulceration, and primary anatomic site. The median overall survival for MM patients with GNAQ mutations (16.0 versus 26.0 months, P = 0.031) or GNA11 mutations (15.0 versus 26.0 months, P = 0.039) were significantly shorter than those for patients with wild-type GNAQ and GNA11, respectively. Our study suggests that GNAQ and GNA11 mutations occur frequently in MM and may be a prognostic factor for MM. Our data implicate that GNAQ/11 may be potential targets for targeted therapy of MM. Copyright © 2016 Elsevier Ltd. All rights reserved.

Characterization and Targeting of the Aldehyde Dehydrogenase Subpopulation in Ovarian Cancer

DTIC Science & Technology

2016-10-01

and p21 Upregulation by Combinatorial Epigallocatechin Gallate and Sulforaphane. J Oncol, 2013: 872957, 2013. o Schultz MJ, Swindall AF, Wright JW...Sztul ES, Landen CN, Bellis SL. ST6Gal- I sialyltransferase confers cisplatin resistance in ovarian tumor cells. J Ovar Res, 6(1): 25, 2013. o...Erickson BK, Conner MG, Landen CN Jr. The Role of the Fallopian Tube in the Origin of Ovarian Cancer. Am J Obstet Gynecol, 209 (5): 409-14, 2013. o

Targeting Androgen Receptor by Lysosomal Degradation in Prostate Cancer

DTIC Science & Technology

2015-11-01

transport of TFEB, Autophagy 8 (2012) 903-914. [7] J. Brugarolas, K. Lei , R.L. Hurley, B.D. Manning, J.H. Reiling, E. Hafen, L.A. Witters, L.W. Ellisen...chromatography ~ anti-FLAG immunoprecipitation B D EWS pos~t~on mass pept~ de 416-429 1449 .66 GDATVSYEDPPTAK 571-594 2289.08 GGPGGMRGGRGGLMDRGGPGGMFR...vector 1 2 3 -- FLAG-His EWS-Fii-1 4 5 6 - FLAG tubulin c RNA helicase A pos~t~on mass pept~ de 121-141 2161 .97 AENNSEVGASGYGVPGPTWDR 200-209

RNAi-Based Suppressor Screens Reveal Genetic Interactions Between the CRL2LRR-1 E3-Ligase and the DNA Replication Machinery in Caenorhabditis elegans

PubMed Central

Ossareh-Nazari, Batool; Katsiarimpa, Anthi; Merlet, Jorge; Pintard, Lionel

2016-01-01

Cullin-RING E3-Ligases (CRLs), the largest family of E3 ubiquitin-Ligases, regulate diverse cellular processes by promoting ubiquitination of target proteins. The evolutionarily conserved Leucine Rich Repeat protein 1 (LRR-1) is a substrate-recognition subunit of a CRL2LRR-1 E3-ligase. Here we provide genetic evidence supporting a role of this E3-enzyme in the maintenance of DNA replication integrity in Caenorhabditis elegans. Through RNAi-based suppressor screens of lrr-1(0) and cul-2(or209ts) mutants, we identified two genes encoding components of the GINS complex, which is part of the Cdc45-MCM-GINS (CMG) replicative helicase, as well as CDC-7 and MUS-101, which drives the assembly of the CMG helicase during DNA replication. In addition, we identified the core components of the ATR/ATL-1 DNA replication checkpoint pathway (MUS-101, ATL-1, CLSP-1, CHK-1). These results suggest that the CRL2LRR-1 E3-ligase acts to modify or degrade factor(s) that would otherwise misregulate the replisome, eventually leading to the activation of the DNA replication checkpoint. PMID:27543292

1. GENERAL VIEW OF ROUTE 209 LOOKING NORTH SHOWING SLEEPING ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. GENERAL VIEW OF ROUTE 209 LOOKING NORTH SHOWING SLEEPING BEAR INN, SLEEPING BEAR INN GARAGE AND DORMITORY, D.H. DAY STORE, RESTROOM, AND GARAGE - Glen Haven Historic District, Route 209, Glen Arbor, Leelanau County, MI

7 CFR 1450.209 - Signup.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Signup. 1450.209 Section 1450.209 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Establishment...

7 CFR 1450.209 - Signup.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 10 2012-01-01 2012-01-01 false Signup. 1450.209 Section 1450.209 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Establishment...

7 CFR 1450.209 - Signup.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 10 2013-01-01 2013-01-01 false Signup. 1450.209 Section 1450.209 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Establishment...

7 CFR 1450.209 - Signup.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 10 2014-01-01 2014-01-01 false Signup. 1450.209 Section 1450.209 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Establishment...

A modeling approach to compare ΣPCB concentrations between congener-specific analyses

USGS Publications Warehouse

Gibson, Polly P.; Mills, Marc A.; Kraus, Johanna M.; Walters, David M.

2017-01-01

Changes in analytical methods over time pose problems for assessing long-term trends in environmental contamination by polychlorinated biphenyls (PCBs). Congener-specific analyses vary widely in the number and identity of the 209 distinct PCB chemical configurations (congeners) that are quantified, leading to inconsistencies among summed PCB concentrations (ΣPCB) reported by different studies. Here we present a modeling approach using linear regression to compare ΣPCB concentrations derived from different congener-specific analyses measuring different co-eluting groups. The approach can be used to develop a specific conversion model between any two sets of congener-specific analytical data from similar samples (similar matrix and geographic origin). We demonstrate the method by developing a conversion model for an example data set that includes data from two different analytical methods, a low resolution method quantifying 119 congeners and a high resolution method quantifying all 209 congeners. We used the model to show that the 119-congener set captured most (93%) of the total PCB concentration (i.e., Σ209PCB) in sediment and biological samples. ΣPCB concentrations estimated using the model closely matched measured values (mean relative percent difference = 9.6). General applications of the modeling approach include (a) generating comparable ΣPCB concentrations for samples that were analyzed for different congener sets; and (b) estimating the proportional contribution of different congener sets to ΣPCB. This approach may be especially valuable for enabling comparison of long-term remediation monitoring results even as analytical methods change over time. 

1. EXTERIOR VIEW OF 209 WARE STREET LOOKING SOUTH. THIS ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. EXTERIOR VIEW OF 209 WARE STREET LOOKING SOUTH. THIS STRUCTURE WAS ONE OF APPROXIMATELY SEVENTEEN DUPLEXES BUILT AS THE ORIGINAL WORKER HOUSING FOR THE LaGRANGE COTTON MILLS, LATER KNOWN AS CALUMET MILL. LaGRANGE MILLS (1888-89) WAS THE FIRST COTTON MILL IN LaGRANGE. NOTE THE GABLE-ON-HIP ROOF FORM AND TWO IDENTICAL STRUCTURES VISIBLE TO THE LEFT. - 209 Ware Street (House), 209 Ware Street, La Grange, Troup County, GA

Studies on the interaction of BDE-47 and BDE-209 with acetylcholinesterase (AChE) based on the neurotoxicity through fluorescence, UV-vis spectra, and molecular docking.

PubMed

Wang, Shutao; Wu, Chuan; Liu, Zhisheng; You, Hong

2018-05-01

The neurotoxicity of polybrominated diphenyl ethers (PBDEs) has been of concern. Acetylcholinesterase (AChE) is a critical enzyme in the central and peripheral nervous system related to neurotoxicity. The interaction between BDE-47, BDE-209, and AChE was investigated through fluorescence and UV-vis spectra combined with molecular docking. Both BDE-47 and BDE-209 bound with AChE and changed the microenvironment of some amino acid residues, resulting in a change of AChE conformation. Hydrophobic interaction is the main binding force between BDE-47, BDE-209, and AChE, and electrostatic interaction exists according to the thermodynamic parameters of the interaction between them. A hydrophobic interaction of BDE-47-AChE and BDE-209-AChE has been confirmed through molecular docking to dominate the binding force. The binding constants of BDE-47-AChE and BDE-209-AChE were 4.2 × 10 4 and 4.1 × 10 4  L/mol, respectively, and the lowest binding energies of BDE-47-AChE and BDE-209-AChE were -7.8 and -5.9 kJ/mol, respectively. BDE-47 is more likely to bind with AChE than BED-209. Copyright © 2018 Elsevier B.V. All rights reserved.

47 CFR 20.9 - Commercial mobile radio service.

Code of Federal Regulations, 2010 CFR

2010-10-01

... presumption that Personal Communications Service, VHF Public Coast, and AMTS Stations are commercial mobile... 47 Telecommunication 2 2010-10-01 2010-10-01 false Commercial mobile radio service. 20.9 Section 20.9 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES...

49 CFR 1540.209 - Fees for security threat assessment.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 9 2014-10-01 2014-10-01 false Fees for security threat assessment. 1540.209 Section 1540.209 Transportation Other Regulations Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY CIVIL AVIATION SECURITY...

5 CFR 430.209 - Agency responsibilities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 430.209 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERFORMANCE MANAGEMENT Performance Appraisal for General Schedule, Prevailing Rate, and Certain Other Employees § 430.209... the employee's most recent ratings of record, and any subsequent performance ratings, when an employee...

5 CFR 430.209 - Agency responsibilities.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 430.209 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERFORMANCE MANAGEMENT Performance Appraisal for General Schedule, Prevailing Rate, and Certain Other Employees § 430.209... the employee's most recent ratings of record, and any subsequent performance ratings, when an employee...

40 CFR 61.209 - Required records.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Required records. 61.209 Section 61.209 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standards for Radon Emissions From...

40 CFR 61.209 - Required records.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 8 2011-07-01 2011-07-01 false Required records. 61.209 Section 61.209 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standards for Radon Emissions From...

Application of the WFD cost proportionality principle to diffuse pollution mitigation: a case study for Scottish Lochs.

PubMed

Vinten, A J A; Martin-Ortega, J; Glenk, K; Booth, P; Balana, B B; MacLeod, M; Lago, M; Moran, D; Jones, M

2012-04-30

The Water Framework Directive (WFD) aims to deliver good ecological status (GES) for Europe's waters. It prescribes the use of economic principles, such as derogation from GES on grounds of disproportionate costs of mitigation. This paper proposes an application of the proportionality principle to mitigation of phosphorus (P) pollution of 544 Scottish lochs at national and local water body scales. P loading estimates were derived from a national diffuse pollution screening tool. For 293 of these lochs (31% of the loch area), GES already occurred. Mitigation cost-effectiveness was assessed using combined mitigation cost curves for managed grassland, rough grazing, arable land, sewage and septic tank sources. These provided sufficient mitigation (92% of national P load) for GES to be achieved on another 31% of loch area at annualised cost of £2.09 m/y. Mitigation of the residual P loading preventing other lochs achieving GES was considered by using a "mop-up" cost of £200/kg P (assumed cost effectiveness of removal of P directly from lochs), leading to a total cost of £189 m/y. Lochs were ranked by mitigation costs per loch area to give a national scale marginal mitigation cost curve. A published choice experiment valuation of WFD targets for Scottish lochs was used to estimate marginal benefits at national scale and combined with the marginal cost curve. This gave proportionate costs of £5.7 m/y leading to GES in 72% of loch area. Using national mean marginal benefits with a scheme to estimate changes in individual loch value with P loading gave proportionate costs of £25.6 m/y leading to GES in 77% of loch area (491 lochs). Copyright © 2011 Elsevier Ltd. All rights reserved.

Microscopic few-body and Gaussian-shaped density distributions for the analysis of the 6He exotic nucleus with different target nuclei

NASA Astrophysics Data System (ADS)

Aygun, M.; Kucuk, Y.; Boztosun, I.; Ibraheem, Awad A.

2010-12-01

The elastic scattering angular distributions of 6He projectile on different medium and heavy mass target nuclei including 12C, 27Al, 58Ni, 64Zn, 65Cu, 197Au, 208Pb and 209Bi have been examined by using the few-body and Gaussian-shaped density distributions at various energies. The microscopic real parts of the complex nuclear optical potential have been obtained by using the double-folding model for each of the density distributions and the phenomenological imaginary potentials have been taken as the Woods-Saxon type. Comparative results of the few-body and Gaussian-shaped density distributions together with the experimental data are presented within the framework of the optical model.

49 CFR 24.209 - Relocation payments not considered as income.

Code of Federal Regulations, 2010 CFR

2010-10-01

....209 Section 24.209 Transportation Office of the Secretary of Transportation UNIFORM RELOCATION... assistance under the Social Security Act (42 U.S. Code 301 et seq.) or any other Federal law, except for any Federal law providing low-income housing assistance. ...

18 CFR 154.209 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false [Reserved] 154.209 Section 154.209 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER NATURAL GAS ACT RATE SCHEDULES AND TARIFFS Procedures for Changing...

18 CFR 154.209 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false [Reserved] 154.209 Section 154.209 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER NATURAL GAS ACT RATE SCHEDULES AND TARIFFS Procedures for Changing...

18 CFR 154.209 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false [Reserved] 154.209 Section 154.209 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER NATURAL GAS ACT RATE SCHEDULES AND TARIFFS Procedures for Changing...

18 CFR 154.209 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false [Reserved] 154.209 Section 154.209 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER NATURAL GAS ACT RATE SCHEDULES AND TARIFFS Procedures for Changing...

18 CFR 154.209 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false [Reserved] 154.209 Section 154.209 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER NATURAL GAS ACT RATE SCHEDULES AND TARIFFS Procedures for Changing...

40 CFR 6.209 - Filing requirements for EPA EISs.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Section 6.209 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROCEDURES FOR IMPLEMENTING THE NATIONAL ENVIRONMENTAL POLICY ACT AND ASSESSING THE ENVIRONMENTAL EFFECTS ABROAD OF EPA ACTIONS EPA's NEPA Environmental Review Procedures § 6.209 Filing requirements for EPA EISs. (a) The...

30 CFR 285.207-285.209 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-07-01

....209 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases General Lease Information §§ 285.207—285.209 [Reserved] Competitive Lease Process ...

24 CFR 115.209 - Technical assistance.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false Technical assistance. 115.209 Section 115.209 Housing and Urban Development Regulations Relating to Housing and Urban Development OFFICE OF ASSISTANT SECRETARY FOR EQUAL OPPORTUNITY, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT FAIR...

24 CFR 115.209 - Technical assistance.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 1 2014-04-01 2014-04-01 false Technical assistance. 115.209 Section 115.209 Housing and Urban Development Regulations Relating to Housing and Urban Development OFFICE OF ASSISTANT SECRETARY FOR EQUAL OPPORTUNITY, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT FAIR...

24 CFR 115.209 - Technical assistance.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 1 2013-04-01 2013-04-01 false Technical assistance. 115.209 Section 115.209 Housing and Urban Development Regulations Relating to Housing and Urban Development OFFICE OF ASSISTANT SECRETARY FOR EQUAL OPPORTUNITY, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT FAIR...

24 CFR 115.209 - Technical assistance.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Technical assistance. 115.209 Section 115.209 Housing and Urban Development Regulations Relating to Housing and Urban Development OFFICE OF ASSISTANT SECRETARY FOR EQUAL OPPORTUNITY, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT FAIR...

40 CFR 240.209-3 - Recommended procedures: Operations.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Occupational Respiratory Disease, National Institute for Occupational Safety and Health, Morgantown, W. Va. (c... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommended procedures: Operations. 240.209-3 Section 240.209-3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED...

40 CFR 240.209-3 - Recommended procedures: Operations.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Occupational Respiratory Disease, National Institute for Occupational Safety and Health, Morgantown, W. Va. (c... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Recommended procedures: Operations. 240.209-3 Section 240.209-3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED...

40 CFR 240.209-3 - Recommended procedures: Operations.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Occupational Respiratory Disease, National Institute for Occupational Safety and Health, Morgantown, W. Va. (c... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Recommended procedures: Operations. 240.209-3 Section 240.209-3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED...

48 CFR 1515.209 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2012 CFR

2012-10-01

... and contract clauses. 1515.209 Section 1515.209 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Solicitation and Receipt... selection and their relative importance in each solicitation. (a) The contracting officer shall insert the...

48 CFR 1515.209 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... and contract clauses. 1515.209 Section 1515.209 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Solicitation and Receipt... selection and their relative importance in each solicitation. (a) The contracting officer shall insert the...

48 CFR 1515.209 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

... and contract clauses. 1515.209 Section 1515.209 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Solicitation and Receipt... selection and their relative importance in each solicitation. (a) The contracting officer shall insert the...

48 CFR 1515.209 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

... and contract clauses. 1515.209 Section 1515.209 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Solicitation and Receipt... selection and their relative importance in each solicitation. (a) The contracting officer shall insert the...

48 CFR 1552.209-71 - Organizational conflicts of interest.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Organizational conflicts of interest. 1552.209-71 Section 1552.209-71 Federal Acquisition Regulations System ENVIRONMENTAL... accomplished through simplified acquisition procedures, use of the clause is optional. Organizational Conflicts...

48 CFR 1552.209-71 - Organizational conflicts of interest.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Organizational conflicts of interest. 1552.209-71 Section 1552.209-71 Federal Acquisition Regulations System ENVIRONMENTAL... accomplished through simplified acquisition procedures, use of the clause is optional. Organizational Conflicts...

48 CFR 1552.209-71 - Organizational conflicts of interest.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Organizational conflicts of interest. 1552.209-71 Section 1552.209-71 Federal Acquisition Regulations System ENVIRONMENTAL... accomplished through simplified acquisition procedures, use of the clause is optional. Organizational Conflicts...

33 CFR 135.209 - Guaranty as evidence.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Guaranty as evidence. 135.209 Section 135.209 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION COMPENSATION FUND...

33 CFR 136.209 - Proof.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Proof. 136.209 Section 136.209 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS PROCEDURES; DESIGNATION OF...

33 CFR 135.209 - Guaranty as evidence.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Guaranty as evidence. 135.209 Section 135.209 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION COMPENSATION FUND...

33 CFR 135.209 - Guaranty as evidence.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Guaranty as evidence. 135.209 Section 135.209 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION COMPENSATION FUND...

33 CFR 136.209 - Proof.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Proof. 136.209 Section 136.209 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS PROCEDURES; DESIGNATION OF...

33 CFR 135.209 - Guaranty as evidence.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Guaranty as evidence. 135.209 Section 135.209 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION COMPENSATION FUND...

33 CFR 136.209 - Proof.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Proof. 136.209 Section 136.209 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS PROCEDURES; DESIGNATION OF...

33 CFR 135.209 - Guaranty as evidence.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Guaranty as evidence. 135.209 Section 135.209 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION COMPENSATION FUND...

33 CFR 136.209 - Proof.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Proof. 136.209 Section 136.209 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS PROCEDURES; DESIGNATION OF...

33 CFR 136.209 - Proof.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Proof. 136.209 Section 136.209 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS PROCEDURES; DESIGNATION OF...

47 CFR 90.209 - Bandwidth limitations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 5 2010-10-01 2010-10-01 false Bandwidth limitations. 90.209 Section 90.209 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND... not necessarily indicate the bandwidth occupied by the emission at any instant. In those cases where...

48 CFR 836.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2012 CFR

2012-10-01

... with architect-engineer firms. 836.209 Section 836.209 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER...-engineer firms. (a) When the contracting officer considers it necessary or advantageous to award a contract...

48 CFR 836.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... with architect-engineer firms. 836.209 Section 836.209 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER...-engineer firms. (a) When the contracting officer considers it necessary or advantageous to award a contract...

48 CFR 836.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... with architect-engineer firms. 836.209 Section 836.209 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER...-engineer firms. (a) When the contracting officer considers it necessary or advantageous to award a contract...

48 CFR 836.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2014 CFR

2014-10-01

... with architect-engineer firms. 836.209 Section 836.209 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER...-engineer firms. (a) When the contracting officer considers it necessary or advantageous to award a contract...

48 CFR 836.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2013 CFR

2013-10-01

... with architect-engineer firms. 836.209 Section 836.209 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER...-engineer firms. (a) When the contracting officer considers it necessary or advantageous to award a contract...

40 CFR 240.209-2 - Recommended procedures: Design.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Design. 240.209-2 Section 240.209-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures...

5 CFR 353.209 - Retention protections.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Retention protections. 353.209 Section 353.209 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS RESTORATION... protections. (a) During uniformed service. An employee may not be demoted or separated (other than military...

5 CFR 843.209 - Waiver of notification requirement.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Waiver of notification requirement. 843.209 Section 843.209 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES RETIREMENT SYSTEM-DEATH BENEFITS AND EMPLOYEE REFUNDS One-time...

41 CFR 101-29.209 - Purchase description.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Purchase description. 101-29.209 Section 101-29.209 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 29-FEDERAL PRODUCT...

41 CFR 101-6.209 - Compliance information.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Compliance information. 101-6.209 Section 101-6.209 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 6-MISCELLANEOUS REGULATIONS 6.2...

Effects of decabromodiphenyl ether and planting on the abundance and community composition of nitrogen-fixing bacteria and ammonia oxidizers in mangrove sediments: A laboratory microcosm study.

PubMed

Chen, Juan; Wang, Pei-Fang; Wang, Chao; Wang, Xun; Gao, Han

2018-03-01

While nitrogen (N) fixation and ammonia oxidation by microorganisms are two important N cycling processes, little is known about how the microbes that drive these two processes respond when sediments are contaminated with persistent organic pollutants. In this study, we carried out a laboratory microcosm experiment to examine the effects of decabromodiphenyl ether (BDE-209), either on its own or combined with a common mangrove species, Avicennia marina, on the abundance, diversity, and community composition of N-fixing bacteria (NFB) and ammonia-oxidizing archaea (AOA) and bacteria (AOB) in mangrove sediments. The sediments were very N-limited after one year. The rates of N fixation and NFB abundance were significantly higher in the sediments that contaminated by BDE-209, especially in the planted sediment, indicating that both BDE-209 and planting stimulated N fixation in N-limited mangrove sediments. In contrast, the potential nitrification rate and abundance of AOA and AOB decreased significantly under BDE-209 and planting, and the inhibitory effects were stronger in the sediment with both planting and BDE-209 than in the sediments with either BDE-209 or planting. The results from pyrosequencing showed that the richness and diversity of NFB increased, while those of AOA and AOB decreased, in the sediments treated with BDE-209 only and with BDE-209 combined with planting. The community compositions of NFB, AOA, and AOB in the sediments shifted significantly because of BDE-209, either alone or particularly when combined with planting, as shown by the increases in some NFB from the Proteobacteria phylum and decreases in AOA in the Nitrosopumilus genus and AOB in the Nitrosospira genus, respectively. Copyright © 2017 Elsevier B.V. All rights reserved.

DNA methylation and copy number variation analyses of human embryonic stem cell-derived neuroprogenitors after low-dose decabromodiphenyl ether and/or bisphenol A exposure.

PubMed

Du, L; Sun, W; Li, X M; Li, X Y; Liu, W; Chen, D

2018-05-01

The polybrominated diphenyl ether flame retardants decabromodiphenyl ether (BDE-209) and bisphenol A (BPA) are environmental contaminants that can cross the placenta and exert toxicity in the developing fetal nervous system. Copy number variants (CNVs) play a role in a number of genetic disorders and may be implicated in BDE-209/BPA teratogenicity. In this study, we found that BDE-209 and/or BPA exposure decreased neural differentiation efficiency of human embryonic stem cells (hESCs), although there was a >90% induction of neuronal progenitor cells (NPCs) from exposed hESCs. However, the mean of CNV numbers in the NPCs with BDE-209 + BPA treatment was significantly higher compared to the other groups, whereas DNA methylation was lower and DNA methyltransferase(DNMT1 and DNMT3A) expression were significantly decreased in all of the BDE-209 and/or BPA treatment groups compared with the control groups. The number of CNVs in chromosomes 3, 4, 11, 22, and X in NPCs with BDE-209 and/or BPA exposure was higher compared to the control group. In addition, CNVs in chromosomes 7, 8, 14, and 16 were stable in hESCs and hESCs-derived NPCs irrespective of BDE-209/BPA exposure, and CNVs in chromosomes 20 q11.21 and 16 p13.11 might be induced by neural differentiation. Thus, BDE-209/BPA exposure emerges as a potential source of CNVs distinct from neural differentiation by itself. BDE-209 and/or BPA exposure may cause genomic instability in cultured stem cells via reduced activity of DNA methyltransferase, suggesting a new mechanism of human embryonic neurodevelopmental toxicity caused by this class of environmental toxins.

Toxicological effects on earthworms (Eisenia fetida) exposed to sub-lethal concentrations of BDE-47 and BDE-209 from a metabolic point.

PubMed

Liang, Ruoyu; Chen, Juan; Shi, Yajuan; Lu, Yonglong; Sarvajayakesavalu, Suriyanarayanan; Xu, Xiangbo; Zheng, Xiaoqi; Khan, Kifayatullah; Su, Chao

2018-05-15

Earthworms improve the soil fertility and they are also sensitive to soil contaminants. Earthworms (Eisenia fetida), standard reference species, were usually chosen to culture and handle for toxicity tests. Metabolic responses in earthworms exposed to 2, 2', 4, 4'-tetrabromodiphenyl ether (BDE-47) and decabromodiphenyl ether (BDE-209) were inhibitory and interfered with basal metabolism. In this study, 1 H-NMR based metabolomics was used to identify sensitive biomarkers and explore metabolic responses of earthworms under sub-lethal BDE-47 and BDE-209 concentrations for 14 days. The results revealed that lactate was accumulated in earthworms exposed to BDE-47 and BDE-209. Glutamate increased significantly when the concentration of BDE-47 and BDE-209 reached 10 mg/kg. The BDE-47 exposure above 50 mg/kg concentration decreased the content of fumarate significantly, which was noticed different from that of BDE-209. Whereas, the BDE-207 or BDE-209 exposure increased the protein degradation into amino acids in vivo. The increased betaine content indicated that earthworms may maintain the cell osmotic pressure and protected enzyme activity by metabolic regulation. Moreover, the BDE-47 and BDE-209 exposure at 10 mg/kg changed most of the metabolites significantly, indicating that the metabolic responses were more sensitive than growth inhibition and gene expression. The metabolomics results revealed the toxic modes of BDE-47 and BDE-209 act on the osmoregulation, energy metabolism, nerve activities, tricarboxylic acid cycle and amino acids metabolism. Furthermore, our results highlighted that the 1 H-NMR based metabolomics is a strong tool for identifying sensitive biomarkers and eco-toxicological assessment. Copyright © 2018 Elsevier Ltd. All rights reserved.

Antibiotic drug rifabutin is effective against lung cancer cells by targeting the eIF4E-β-catenin axis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Ji; Huang, Yijiang; Gao, Yunsuo

The essential roles of overexpression of eukaryotic translation initiation factor 4E (eIF4E) and aberrant activation of β-catenin in lung cancer development have been recently identified. However, whether there is a direct connection between eIF4E overexpression and β-catenin activation in lung cancer cells is unknown. In this study, we show that antibiotic drug rifabutin targets human lung cancer cells via inhibition of eIF4E-β-catenin axis. Rifabutin is effectively against lung cancer cells in in vitro cultured cells and in vivo xenograft mouse model through inhibiting proliferation and inducing apoptosis. Mechanistically, eIF4E regulates β-catenin activity in lung cancer cells as shown by the increased β-cateninmore » phosphorylation and activity in cells overexpressing eIF4E, and furthermore that the regulation is dependent on phosphorylation at S209. Rifabutin suppresses eIF4E phosphorylation, leads to decreased β-catenin phosphorylation and its subsequent transcriptional activities. Depletion of eIF4E abolishes the inhibitory effects of rifabutin on β-catenin activities and overexpression of β-catenin reverses the inhibitory effects of rifabutin on cell growth and survival, further confirming that rifabutin acts on lung cancer cells via targeting eIF4E- β-catenin axis. Our findings identify the eIF4E- β-catenin axis as a critical regulator of lung cancer cell growth and survival, and suggest that its pharmacological inhibition may be therapeutically useful in lung cancer. - Highlights: • Rifabutin targets EGFR-mutated lung cancer cells in vitro and in vivo. • eIF4E phosphorylation regulates β-catenin activity in lung cancer cells. • Rifabutin acts on lung cancer cells via eIF4E- β-catenin axis. • Rifabutin can be repurposed for lung cancer treatment.« less

Biodegradation of Decabromodiphenyl Ether (BDE-209) by Crude Enzyme Extract from Pseudomonas aeruginosa.

PubMed

Liu, Yu; Gong, Ai-Jun; Qiu, Li-Na; Li, Jing-Rui; Li, Fu-Kai

2015-09-18

The biodegradation effect and mechanism of decabromodiphenyl ether (BDE-209) by crude enzyme extract from Pseudomonas aeruginosa were investigated. The results demonstrated that crude enzyme extract exhibited obviously higher degradation efficiency and shorter biodegradation time than Pseudomonas aeruginosa itself. Under the optimum conditions of pH 9.0, 35 °C and protein content of 2000 mg/L, 92.77% of the initial BDE-209 (20 mg/L) was degraded after 5 h. A BDE-209 biodegradation pathway was proposed on the basis of the biodegradation products identified by GC-MS analysis. The biodegradation mechanism showed that crude enzyme extract degraded BDE-209 into lower brominated PBDEs and OH-PBDEs through debromination and hydroxylation of the aromatic rings.

Biodegradation of Decabromodiphenyl Ether (BDE-209) by Crude Enzyme Extract from Pseudomonas aeruginosa

PubMed Central

Liu, Yu; Gong, Ai-Jun; Qiu, Li-Na; Li, Jing-Rui; Li, Fu-Kai

2015-01-01

The biodegradation effect and mechanism of decabromodiphenyl ether (BDE-209) by crude enzyme extract from Pseudomonas aeruginosa were investigated. The results demonstrated that crude enzyme extract exhibited obviously higher degradation efficiency and shorter biodegradation time than Pseudomonas aeruginosa itself. Under the optimum conditions of pH 9.0, 35 °C and protein content of 2000 mg/L, 92.77% of the initial BDE-209 (20 mg/L) was degraded after 5 h. A BDE-209 biodegradation pathway was proposed on the basis of the biodegradation products identified by GC-MS analysis. The biodegradation mechanism showed that crude enzyme extract degraded BDE-209 into lower brominated PBDEs and OH-PBDEs through debromination and hydroxylation of the aromatic rings. PMID:26393637

The G209A mutation in the alpha-synuclein gene is not detected in familial cases of Parkinson disease in non-Greek and/or Italian populations.

PubMed

Wang, W W; Khajavi, M; Patel, B J; Beach, J; Jankovic, J; Ashizawa, T

1998-12-01

To determine whether the G-to-A substitution at nucleotide 209 (G209A) mutation in the alpha-synuclein gene is responsible for familial Parkinson disease (PD) in the US population. Polymerase chain reaction-based DNA analysis of consecutive patients with PD and family history of PD. A university-affiliated movement disorder clinic and a Veterans Affairs clinical research laboratory. Forty-four patients with PD and family history of PD and 29 patients with sporadic PD, all with no known Greek and/or Italian background. None of the DNA samples showed the G209A mutation. The G209A mutation is rare in US patients with familial PD.

29 CFR 1603.209 - Filing and service.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 4 2013-07-01 2013-07-01 false Filing and service. 1603.209 Section 1603.209 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF...

29 CFR 1603.209 - Filing and service.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 4 2014-07-01 2014-07-01 false Filing and service. 1603.209 Section 1603.209 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF...

29 CFR 1603.209 - Filing and service.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 4 2012-07-01 2012-07-01 false Filing and service. 1603.209 Section 1603.209 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF...

29 CFR 1603.209 - Filing and service.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 4 2011-07-01 2011-07-01 false Filing and service. 1603.209 Section 1603.209 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF...

29 CFR 1603.209 - Filing and service.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 4 2010-07-01 2010-07-01 false Filing and service. 1603.209 Section 1603.209 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF...

30 CFR 585.207-585.209 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-07-01

....209 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY AND ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases General Lease Information §§ 585.207-585.209 [Reserved] Competitive Lease Process ...

30 CFR 285.207-285.209 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-07-01

....209 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases General Lease Information §§ 285.207—285.209 [Reserved...

30 CFR 585.207-585.209 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-07-01

....209 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY AND ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases General Lease Information §§ 585.207-585.209 [Reserved] Competitive Lease Process ...

30 CFR 585.207-585.209 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

....209 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY AND ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases General Lease Information §§ 585.207-585.209 [Reserved] Competitive Lease Process ...

48 CFR 1552.209-71 - Organizational conflicts of interest.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Organizational conflicts of interest. 1552.209-71 Section 1552.209-71 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION... through simplified acquisition procedures, use of the clause is optional. Organizational Conflicts of...

40 CFR 240.209-3 - Recommended procedures: Operations.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Occupational Respiratory Disease, National Institute for Occupational Safety and Health, Morgantown, W. Va. (c... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Recommended procedures: Operations. 240.209-3 Section 240.209-3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID...

24 CFR 1710.209 - Title and land use.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false Title and land use. 1710.209 Section 1710.209 Housing and Urban Development Regulations Relating to Housing and Urban Development... URBAN DEVELOPMENT (INTERSTATE LAND SALES REGISTRATION PROGRAM) LAND REGISTRATION Reporting Requirements...

24 CFR 1710.209 - Title and land use.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 5 2014-04-01 2014-04-01 false Title and land use. 1710.209 Section 1710.209 Housing and Urban Development Regulations Relating to Housing and Urban Development... URBAN DEVELOPMENT (INTERSTATE LAND SALES REGISTRATION PROGRAM) LAND REGISTRATION Reporting Requirements...

24 CFR 1710.209 - Title and land use.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 5 2013-04-01 2013-04-01 false Title and land use. 1710.209 Section 1710.209 Housing and Urban Development Regulations Relating to Housing and Urban Development... URBAN DEVELOPMENT (INTERSTATE LAND SALES REGISTRATION PROGRAM) LAND REGISTRATION Reporting Requirements...

24 CFR 1710.209 - Title and land use.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 5 2012-04-01 2012-04-01 false Title and land use. 1710.209 Section 1710.209 Housing and Urban Development Regulations Relating to Housing and Urban Development... URBAN DEVELOPMENT (INTERSTATE LAND SALES REGISTRATION PROGRAM) LAND REGISTRATION Reporting Requirements...

31 CFR 800.209 - Critical technologies.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Critical technologies. 800.209 Section... TAKEOVERS BY FOREIGN PERSONS Definitions § 800.209 Critical technologies. The term critical technologies..., nuclear nonproliferation, or missile technology), as well as those that are controlled for reasons of...