A rapid leaf-disc sampler for psychrometric water potential measurements.
Wullschleger, S D; Oosterhuis, D M
1986-06-01
An instrument was designed which facilitates faster and more accurate sampling of leaf discs for psychrometric water potential measurements. The instrument consists of an aluminum housing, a spring-loaded plunger, and a modified brass-plated cork borer. The leaf-disc sampler was compared with the conventional method of sampling discs for measurement of leaf water potential with thermocouple psychrometers on a range of plant material including Gossypium hirsutum L., Zea mays L., and Begonia rex-cultorum L. The new sampler permitted a leaf disc to be excised and inserted into the psychrometer sample chamber in less than 7 seconds, which was more than twice as fast as the conventional method. This resulted in more accurate determinations of leaf water potential due to reduced evaporative water losses. The leaf-disc sampler also significantly reduced sample variability between individual measurements. This instrument can be used for many other laboratory and field measurements that necessitate leaf disc sampling.
A Rapid Leaf-Disc Sampler for Psychrometric Water Potential Measurements 1
Wullschleger, Stan D.; Oosterhuis, Derrick M.
1986-01-01
An instrument was designed which facilitates faster and more accurate sampling of leaf discs for psychrometric water potential measurements. The instrument consists of an aluminum housing, a spring-loaded plunger, and a modified brass-plated cork borer. The leaf-disc sampler was compared with the conventional method of sampling discs for measurement of leaf water potential with thermocouple psychrometers on a range of plant material including Gossypium hirsutum L., Zea mays L., and Begonia rex-cultorum L. The new sampler permitted a leaf disc to be excised and inserted into the psychrometer sample chamber in less than 7 seconds, which was more than twice as fast as the conventional method. This resulted in more accurate determinations of leaf water potential due to reduced evaporative water losses. The leaf-disc sampler also significantly reduced sample variability between individual measurements. This instrument can be used for many other laboratory and field measurements that necessitate leaf disc sampling. PMID:16664879
Disc size regulation in the brood cell building behavior of leaf-cutter bee, Megachile tsurugensis
NASA Astrophysics Data System (ADS)
Kim, Jong-Yoon
2007-12-01
The leaf-cutter bee, Megachile tsurugensis, builds a brood cell in a preexisting tunnel with leaf discs that she cuts in decreasing sizes and assembles them like a Russian matryoshka doll. By experimentally manipulating the brood cell, it was investigated how she regulates the size of leaf discs that fit in the brood cell’s internal volume. When the internal volume was artificially increased by removing a bulk of leaf discs, she decreased the leaf disc size, although increasing it would have made the leaf disc more fitting in the increased internal volume. As a reverse manipulation, when the internal volume was decreased by inserting a group of inner layers of preassembled leaf discs to a brood cell, she decreased the leaf disc size, so that the leaf disc could fit in the decreased internal volume. These results suggest that she uses at least two different mechanisms to regulate the disc size: the use of some internal memory about the degree of building work accomplished in the first and of sensory feedback of dimensional information at the construction site in the second manipulation, respectively. It was concluded that a stigmergic mechanism, an immediate sensory feedback from the brood cell changed by the building work, alone cannot explain the details of the bee’s behavior particularly with respect to her initial response to the first manipulation. For a more complete explanation of the behavior exhibited by the solitary bee, two additional behavioral elements, reinforcement of building activity and processing of dimensional information, were discussed along with stigmergy.
Disc size regulation in the brood cell building behavior of leaf-cutter bee, Megachile tsurugensis.
Kim, Jong-yoon
2007-12-01
The leaf-cutter bee, Megachile tsurugensis, builds a brood cell in a preexisting tunnel with leaf discs that she cuts in decreasing sizes and assembles them like a Russian matryoshka doll. By experimentally manipulating the brood cell, it was investigated how she regulates the size of leaf discs that fit in the brood cell's internal volume. When the internal volume was artificially increased by removing a bulk of leaf discs, she decreased the leaf disc size, although increasing it would have made the leaf disc more fitting in the increased internal volume. As a reverse manipulation, when the internal volume was decreased by inserting a group of inner layers of preassembled leaf discs to a brood cell, she decreased the leaf disc size, so that the leaf disc could fit in the decreased internal volume. These results suggest that she uses at least two different mechanisms to regulate the disc size: the use of some internal memory about the degree of building work accomplished in the first and of sensory feedback of dimensional information at the construction site in the second manipulation, respectively. It was concluded that a stigmergic mechanism, an immediate sensory feedback from the brood cell changed by the building work, alone cannot explain the details of the bee's behavior particularly with respect to her initial response to the first manipulation. For a more complete explanation of the behavior exhibited by the solitary bee, two additional behavioral elements, reinforcement of building activity and processing of dimensional information, were discussed along with stigmergy.
Cottrell, Ted E; Wood, Bruce W; Ni, Xinzhi
2009-04-01
The nature of the interaction between the black pecan aphid, Melanocallis caryaefoliae (Davis) (Hemiptera: Aphididae), and the chlorosis it causes to foliage of its pecan [Carya illinoinensis (Wangenh.) K. Koch)] host is poorly understood. Laboratory experiments were conducted on the settling behavior of the black pecan aphid, when provided chlorotic pecan leaf discs resulting from previous black pecan aphid feeding and nonchlorotic leaf discs, under a normal photoperiod and constant dark. Additionally, aphid development from the first instar to the adult stage was examined when nymphs were either allowed to feed on the same leaf disc or moved daily to a new, nondamaged, same age leaf disc. After 24 h, a significantly higher percentage of black pecan aphids settled on chlorotic than on nonchlorotic leaf discs, regardless of photoperiod. When starting from the first instar, nymphs that were prevented from inducing leaf chlorosis by moving daily to new, same-age leaf discs took approximately 5 d longer to complete development, had a shorter body length, and had higher mortality than when aphids remained on the same leaf disc. These results show that black pecan aphid-induced leaf chlorosis plays an important role in the interaction of the black pecan aphid with its pecan host.
Silver nano fabrication using leaf disc of Passiflora foetida Linn
NASA Astrophysics Data System (ADS)
Lade, Bipin D.; Patil, Anita S.
2017-06-01
The main purpose of the experiment is to develop a greener low cost SNP fabrication steps using factories of secondary metabolites from Passiflora leaf extract. Here, the leaf extraction process is omitted, and instead a leaf disc was used for stable SNP fabricated by optimizing parameters such as a circular leaf disc of 2 cm (1, 2, 3, 4, 5) instead of leaf extract and grade of pH (7, 8, 9, 11). The SNP synthesis reaction is tried under room temperature, sun, UV and dark condition. The leaf disc preparation steps are also discussed in details. The SNP obtained using (1 mM: 100 ml AgNO3+ singular leaf disc: pH 9, 11) is applied against featured room temperature and sun condition. The UV spectroscopic analysis confirms that sun rays synthesized SNP yields stable nano particles. The FTIR analysis confirms a large number of functional groups such as alkanes, alkyne, amines, aliphatic amine, carboxylic acid; nitro-compound, alcohol, saturated aldehyde and phenols involved in reduction of silver salt to zero valent ions. The leaf disc mediated synthesis of silver nanoparticles, minimizes leaf extract preparation step and eligible for stable SNP synthesis. The methods sun and room temperature based nano particles synthesized within 10 min would be use certainly for antimicrobial activity.
Water and Salt Stresses, Kinetin and Protein Synthesis in Tobacco Leaves 1
Ben-Zioni, Aliza; Itai, C.; Vaadia, Y.
1967-01-01
The capacity of tobacco (Nicotiana rustica) leaf discs to incorporate l-leucine 14C into proteins was measured. Leaf discs were obtained from plants which experienced soil water depletion, or which were exposed to a saline or osmotic stress in the root medium. The stresses were brief of relatively short duration and water potential did not decrease below 4 bars in the root media. Leaf discs were sampled 2 hours after stress removal, achieved by reirrigation, or replacement of saline and osmotic solutions with normal nutrient solution. Plants were always turgid when leaves were sampled. All stressed tissues showed reduced capacity to incorporate l-leucine 14C into protein. The reduction was about 50% and could not be attributed either to reduced uptake into the discs, or to possible isotopic dilution. Incorporation decreased progressively with leaf age in control discs as well as in stressed leaf discs. At all ages tested, incorporation in stressed discs was lower than that of the control. Full recovery of incorporation capacity in stressed discs was obtained when discs were sampled 72 hours after stress removal but not earlier. Kinetin pretreatment prior to incubation with labelled leucine partially restored incorporation in stressed discs. The differences in response to kinetin of stressed and control discs suggest a lower endogenous level of cytokinins in the stressed discs. The results were qualitatively similar regardless of the kind of stress given to the plants during pretreatment. This supports the hypothesis that the normal supply of root cytokinins is important in shoot metabolism. PMID:16656515
Snyman, S J; Meyer, G M; Richards, J M; Haricharan, N; Ramgareeb, S; Huckett, B I
2006-10-01
A rapid in vitro protocol using direct somatic embryogenesis and microprojectile bombardment was investigated to establish the developmental phases most suitable for efficient sugarcane transformation. Immature leaf roll disc explants with and without pre-emergent inflorescence tissue were compared. It was shown that for effective transformation to occur, explants should be cultured for several days to allow initiation of embryo development prior to bombardment. Leaf roll discs with pre-emergent inflorescences showed a higher degree of embryogenic competence than non-flowering explants, and transformation efficiency was higher when explants containing floral initials were bombarded. Despite the occurrence of high numbers of phenotypically negative plants, combining the use of inflorescent leaf roll discs with direct embryogenic regeneration has the potential to improve the speed and efficiency of transgenesis in sugarcane.
Abbas, H K; Paul, R N; Riley, R T; Tanaka, T; Shier, W T
1998-12-01
Ultrastructural effects of AAL-toxin TA from Alternaria alternata on black nightshade (Solanum, nigrum L.) leaf discs and correlation with biochemical measures of toxicity. In black nightshade (Solanum nigrum L.) leaf discs floating in solutions of AAL-toxin TA (0.01-200 microM) under continuous light at 25 degrees C, electrolyte leakage, chlorophyll loss, autolysis, and photobleaching were observed within 24 h. Electrolyte leakage, measured by the conductivity increase in the culture medium, began after 12 h with 200 microM AAL-toxin T(A), but was observed after 24 h with 0.01 to 50 microM AAL-toxin T(A), when it ranged from 25%) to 63% of total releasable electrolytes, respectively. After 48 h incubation, leakage ranged from 39% to 79% of total for 0.01 to 200 microM AAL-toxin T(A), respectively, while chlorophyll loss ranged from 5% to 32% of total, respectively. Ultrastructural examination of black night-shade leaf discs floating in 10 microM AAL-toxin TA under continuous light at 25 degrees C revealed cytological damage beginning at 30 h, consistent with the time electrolyte leakage and chlorophyll reduction were observed. After 30 h incubation chloroplast starch grains were enlarged in control leaf discs, but not in AAL-toxin T(A)-treated discs, and the thylakoids of treated tissue contained structural abnormalities. After 36-48 h incubation with 10 microM AAL-toxin T(A), all tissues were destroyed with only cell walls, starch grains, and thylakoid fragments remaining. Toxicity was light-dependent, because leaf discs incubated with AAL-toxin T(A) in darkness for up to 72 h showed little phytotoxic damage. Within 6 h of exposure to > or =0.5 microM toxin, phytosphingosine and sphinganine in black nightshade leaf discs increased markedly, and continued to increase up to 24 h exposure. Thus, phy siological and ultrastructural changes occurred in parallel with disruption of sphingolipid synthesis, consistent with the hypothesis that AAL-toxin T(A) causes phytotoxicity by interrupting sphingolipid biosynthesis, thereby damaging cellular membranes.
Nanjareddy, Kalpana; Arthikala, Manoj-Kumar; Blanco, Lourdes; Arellano, Elizabeth S; Lara, Miguel
2016-06-24
Phaseolus vulgaris is one of the most extensively studied model legumes in the world. The P. vulgaris genome sequence is available; therefore, the need for an efficient and rapid transformation system is more imperative than ever. The functional characterization of P. vulgaris genes is impeded chiefly due to the non-amenable nature of Phaseolus sp. to stable genetic transformation. Transient transformation systems are convenient and versatile alternatives for rapid gene functional characterization studies. Hence, the present work focuses on standardizing methodologies for protoplast isolation from multiple tissues and transient transformation protocols for rapid gene expression analysis in the recalcitrant grain legume P. vulgaris. Herein, we provide methodologies for the high-throughput isolation of leaf mesophyll-, flower petal-, hypocotyl-, root- and nodule-derived protoplasts from P. vulgaris. The highly efficient polyethylene glycol-mannitol magnesium (PEG-MMG)-mediated transformation of leaf mesophyll protoplasts was optimized using a GUS reporter gene. We used the P. vulgaris SNF1-related protein kinase 1 (PvSnRK1) gene as proof of concept to demonstrate rapid gene functional analysis. An RT-qPCR analysis of protoplasts that had been transformed with PvSnRK1-RNAi and PvSnRK1-OE vectors showed the significant downregulation and ectopic constitutive expression (overexpression), respectively, of the PvSnRK1 transcript. We also demonstrated an improved transient transformation approach, sonication-assisted Agrobacterium-mediated transformation (SAAT), for the leaf disc infiltration of P. vulgaris. Interestingly, this method resulted in a 90 % transformation efficiency and transformed 60-85 % of the cells in a given area of the leaf surface. The constitutive expression of YFP further confirmed the amenability of the system to gene functional characterization studies. We present simple and efficient methodologies for protoplast isolation from multiple P. vulgaris tissues. We also provide a high-efficiency and amenable method for leaf mesophyll transformation for rapid gene functional characterization studies. Furthermore, a modified SAAT leaf disc infiltration approach aids in validating genes and their functions. Together, these methods help to rapidly unravel novel gene functions and are promising tools for P. vulgaris research.
Boiça Júnior, Arlindo Leal; De Souza, Bruno Henrique Sardinha; Costa, Eduardo Neves; Ribeiro, Zulene Antonio; Stout, Michael Joseph
2015-02-01
This study aimed to evaluate some factors that influence the expression of antixenosis in soybean genotypes against Anticarsia gemmatalis Hübner and Spodoptera frugiperda (J. E. Smith) (Lepidoptera: Noctuidae). Free-choice and no-choice feeding assays were performed with the resistant soybean genotype IAC 100 and the susceptible genotype BRSGO 8360 using A. gemmatalis and S. frugiperda larvae. The following factors that may affect expression of resistance were evaluated: one larva versus two larvae per leaf disc; use of larvae without prior feeding suspension versus larvae starved for 3 h prior to the assay; leaf discs versus entire leaflets; upper part versus lower part of the plant; and, vegetative versus reproductive growth stages. The level of resistance exhibited by the genotype IAC 100 was high enough to not be obscured by the effects of all factors assayed in the present study upon the feeding preference of A. gemmatalis and S. frugiperda larvae. However, our results demonstrate the importance of knowing the optimal conditions for conducting an assay for evaluating resistance of genotypes for specialist and generalist insect species. Utilization of two larvae of A. gemmatalis per leaf disc, not starved before the assays, with leaf discs from the upper part of plants at the reproductive growth stage provided better discrimination of differences in antixenosis expression in soybean genotypes. For S. frugiperda, use of one larva per leaf disc, not starved before the assays, with leaf discs from the lower part of plants at the reproductive growth stage gave more satisfactory results for feeding preference tests. © The Authors 2015. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
Divilov, Konstantin; Wiesner-Hanks, Tyr; Barba, Paola; Cadle-Davidson, Lance; Reisch, Bruce I
2017-12-01
Quantitative phenotyping of downy mildew sporulation is frequently used in plant breeding and genetic studies, as well as in studies focused on pathogen biology such as chemical efficacy trials. In these scenarios, phenotyping a large number of genotypes or treatments can be advantageous but is often limited by time and cost. We present a novel computational pipeline dedicated to estimating the percent area of downy mildew sporulation from images of inoculated grapevine leaf discs in a manner that is time and cost efficient. The pipeline was tested on images from leaf disc assay experiments involving two F 1 grapevine families, one that had glabrous leaves (Vitis rupestris B38 × 'Horizon' [RH]) and another that had leaf trichomes (Horizon × V. cinerea B9 [HC]). Correlations between computer vision and manual visual ratings reached 0.89 in the RH family and 0.43 in the HC family. Additionally, we were able to use the computer vision system prior to sporulation to measure the percent leaf trichome area. We estimate that an experienced rater scoring sporulation would spend at least 90% less time using the computer vision system compared with the manual visual method. This will allow more treatments to be phenotyped in order to better understand the genetic architecture of downy mildew resistance and of leaf trichome density. We anticipate that this computer vision system will find applications in other pathosystems or traits where responses can be imaged with sufficient contrast from the background.
Marino, John A.; Perfecto, Ivette; Vandermeer, John
2015-01-01
The interaction of crop pests with their natural enemies is a fundament to their control. Natural enemies of fungal pathogens of crops are poorly known relative to those of insect pests, despite the diversity of fungal pathogens and their economic importance. Currently, many regions across Latin America are experiencing unprecedented epidemics of coffee rust (Hemileia vastatrix). Identification of natural enemies of coffee rust could aid in developing management strategies or in pinpointing species that could be used for biocontrol. In the present study, we characterized fungal communities associated with coffee rust lesions by single-molecule DNA sequencing of fungal rRNA gene bar codes from leaf discs (≈28 mm2) containing rust lesions and control discs with no rust lesions. The leaf disc communities were hyperdiverse in terms of fungi, with up to 69 operational taxonomic units (putative species) per control disc, and the diversity was only slightly reduced in rust-infected discs, with up to 63 putative species. However, geography had a greater influence on the fungal community than whether the disc was infected by coffee rust. Through comparisons between control and rust-infected leaf discs, as well as taxonomic criteria, we identified 15 putative mycoparasitic fungi. These fungi are concentrated in the fungal family Cordycipitaceae and the order Tremellales. These data emphasize the complexity of diverse fungi of unknown ecological function within a leaf that might influence plant disease epidemics or lead to the development of species for biocontrol of fungal disease. PMID:26567299
Quantum Yields of CAM Plants Measured by Photosynthetic O2 Exchange 1
Adams, William W.; Nishida, Kojiro; Osmond, C. Barry
1986-01-01
The quantum yield of photosynthetic O2 exchange was measured in eight species of leaf succulents representative of both malic enzyme type and phosphoenolpyruvate carboxykinase type CAM plants. Measurements were made at 25°C and CO2 saturation using a leaf disc O2 electrode system, either during or after deacidification. The mean quantum yield was 0.095 ± 0.012 (sd) moles O2 per mole quanta, which compared with 0.094 ± 0.006 (sd) moles O2 per mole quanta for spinach leaf discs measured under the same conditions. There were no consistent differences in quantum yield between decarboxylation types or during different phases of CAM metabolism. On the basis of current notions of compartmentation of CAM biochemistry, our observations are interpreted to indicate that CO2 refixation is energetically independent of gluconeogenesis during deacidification. PMID:16664793
James, Timothy Y; Marino, John A; Perfecto, Ivette; Vandermeer, John
2016-01-15
The interaction of crop pests with their natural enemies is a fundament to their control. Natural enemies of fungal pathogens of crops are poorly known relative to those of insect pests, despite the diversity of fungal pathogens and their economic importance. Currently, many regions across Latin America are experiencing unprecedented epidemics of coffee rust (Hemileia vastatrix). Identification of natural enemies of coffee rust could aid in developing management strategies or in pinpointing species that could be used for biocontrol. In the present study, we characterized fungal communities associated with coffee rust lesions by single-molecule DNA sequencing of fungal rRNA gene bar codes from leaf discs (≈28 mm(2)) containing rust lesions and control discs with no rust lesions. The leaf disc communities were hyperdiverse in terms of fungi, with up to 69 operational taxonomic units (putative species) per control disc, and the diversity was only slightly reduced in rust-infected discs, with up to 63 putative species. However, geography had a greater influence on the fungal community than whether the disc was infected by coffee rust. Through comparisons between control and rust-infected leaf discs, as well as taxonomic criteria, we identified 15 putative mycoparasitic fungi. These fungi are concentrated in the fungal family Cordycipitaceae and the order Tremellales. These data emphasize the complexity of diverse fungi of unknown ecological function within a leaf that might influence plant disease epidemics or lead to the development of species for biocontrol of fungal disease. Copyright © 2016, American Society for Microbiology. All Rights Reserved.
Piotrzkowski, Natalia; Schillberg, Stefan; Rasche, Stefan
2012-01-01
Transient Agrobacterium-mediated gene expression assays for Nicotiana tabacum (N. tabacum) are frequently used because they facilitate the comparison of multiple expression constructs regarding their capacity for maximum recombinant protein production. However, for three model proteins, we found that recombinant protein accumulation (rpa) was significantly influenced by leaf age and leaf position effects. The ratio between the highest and lowest amount of protein accumulation (max/min ratio) was found to be as high as 11. Therefore, construct-based impacts on the rpa level that are less than 11-fold will be masked by background noise. To address this problem, we developed a leaf disc-based screening assay and infiltration device that allows the rpa level in a whole tobacco plant to be reliably and reproducibly determined. The prototype of the leaf disc infiltration device allows 14 Agrobacterium-mediated infiltration events to be conducted in parallel. As shown for three model proteins, the average max/min rpa ratio was reduced to 1.4 using this method, which allows for a sensitive comparison of different genetic elements affecting recombinant protein expression. PMID:23029251
Leaf-shape effects in electromagnetic wave scattering from vegetation
NASA Technical Reports Server (NTRS)
Karam, Mostafa A.; Fung, Adrian K.
1989-01-01
A vegetation medium is modeled as a half-space of randomly distributed and oriented leaves of arbitrary shape. In accordance with the first-order radiative transfer theory, the backscattering coefficient for such a half-space is expressed in terms of the scattering amplitudes. For disc- or needle-shaped leaves, the generalized Rayleigh-Gans approximation is used to calculate the scattering amplitudes. This approach is valid for leaf dimensions up to the size of the incident wavelength. To examine the leaf-shape effect, elliptic discs are used to model deciduous leaves, and needles are used to model coniferous leaves. The differences between the scattering characteristics of leaves of different shapes are illustrated numerically for various orientations, frequencies, and incidence angles. It is found that the scattering characteristics of elliptic disc-shaped leaves are sensitive to the three angles of orientation and disc ellipticity. In general, both like and cross polarizations may be needed to differentiate the difference in scattering due to the shapes of the leaves.
NASA Technical Reports Server (NTRS)
Van Volkenburgh, E.; Cleland, R. E.; Watanabe, M.
1990-01-01
The quantity and quality of light required for light-stimulated cell expansion in leaves of Phaseolus vulgaris L. have been determined. Seedlings were grown in dim red light (RL; 4 micromoles photons m-2 s-1) until cell division in the primary leaves was completed, then excised discs were incubated in 10 mM sucrose plus 10 mM KCl in a variety of light treatments. The growth response of discs exposed to continuous white light (WL) for 16 h was saturated at 100 micromoles m-2 s-1, and did not show reciprocity. Extensive, but not continuous, illumination was needed for maximal growth. The wavelength dependence of disc expansion was determined from fluence-response curves obtained from 380 to 730 nm provided by the Okazaki Large Spectrograph. Blue (BL; 460 nm) and red light (RL; 660 nm) were most effective in promoting leaf cell growth, both in photosynthetically active and inhibited leaf discs. Far-red light (FR; 730 nm) reduced the effectiveness of RL, but not BL, indicating that phytochrome and a separate blue-light receptor mediate expansion of leaf cells.
Statistics of backscatter radar return from vegetation
NASA Technical Reports Server (NTRS)
Karam, M. A.; Chen, K. S.; Fung, A. K.
1992-01-01
The statistical characteristics of radar return from vegetation targets are investigated through a simulation study based upon the first-order scattered field. For simulation purposes, the vegetation targets are modeled as a layer of randomly oriented and spaced finite cylinders, needles, or discs, or a combination of them. The finite cylinder is used to represent a branch or a trunk, the needle for a stem or a coniferous leaf, and the disc for a decidous leaf. For a plane wave illuminating a vegetation canopy, simulation results show that the signal returned from a layer of disc- or needle-shaped leaves follows the Gamma distribution, and that the signal returned from a layer of branches resembles the log normal distribution. The Gamma distribution also represents the signal returned from a layer of a mixture of branches and leaves regardless of the leaf shapes. Results also indicate that the polarization state does not have a significant impact on signal distribution.
Cottrell, Ted E; Wood, Bruce W; Ni, Xinzhi
2010-11-01
Black pecan aphid, Melanocallis caryaefoliae (Davis) (Hemiptera: Aphididae), feeding elicits localized chlorotic injury to pecan foliage [Carya illinoinensis (Wangenh.) K Koch] and apparent acceleration of leaf senescence and defoliation. The ability of certain plant growth regulators (PGRs) (forchlorfenuron, gibberellic acid and aviglycine) to prevent M. caryaefoliae from triggering pecan leaf chlorosis and senescence-like processes was evaluated on two dates in both 2006 and 2007. Treatments were applied to orchard foliage and used in laboratory leaf-disc bioassays to assess possible reduction in aphid-elicited chlorosis and concomitant effects on aphid mortality and development. Foliage pretreated with forchlorfenuron + gibberellic acid prior to being challenged with aphids resulted in significantly less aphid-elicited chlorosis than did control or aviglycine-treated leaf discs. No PGR affected aphid mortality; however, development time was increased by forchlorfenuron + gibberellic acid in 2006 and by aviglycine + gibberellic acid on one date in 2007. Certain PGRs possess the potential for usage on pecan to protect foliar canopies from M. caryaefoliae via changes in the susceptibility of the host leaf to senescence-like factors being introduced by feeding aphids. This protective effect on host foliage and the associated suppressive effect on development of feeding aphids might also be relevant to pest management programs on other aphid-crop systems in which aphid-elicited chlorosis and senescence-like processes can limit profitability. Published 2010 by John Wiley & Sons, Ltd.
Reis, D F; Machado, M M D; Coutinho, N P; Rangel, J V; Moretti, M S; Morais, P B
2018-04-23
Macroinvertebrate shredders consume preferably leaves conditioned by fungi and bacteria which offer greater palatability to them. Plant species in Cerrado present high concentration of chemical elements such as lignin and cellulose, phenols and tanins thus making them less attractive for shredders consumption and limiting the palatability. This study aimed to evaluate the feeding preference of a macroinvertebrate shredder of the genus Phylloicus for plant material from two different biomes (Cerrado and Mata Atlântica), after conditioning in a stream of Mata Atlântica and observing their physical and chemical characteristics. Senescent leaves were collected, monthly from the litterfall of riparian vegetation in a 500 m stretch of a stream in each biome from August 2014 to January 201. The most abundant species in each stream was selected for the experiment. The experimental design consisted in with two treatments. The first (T1) comprised leaf discs from Chrysophyllum oliviforme (Cerrado species) together with leaf discs of Miconia chartacea (Atlantic Forest species) which were conditioned in the Atlantic Forest stream. The second treatment (T2) involved leaf discs of Miconia chartacea conditioned in Mata Altlântica and Cerrado streams. Both tests had showed significant differences between the two treatments (T1 and T2). For T1, there was consumption of M. chartacea leaf discs by Phylloicus sp., but there was no consumption of C. oliviforme discs. For T2, there was preference for M. chartaceae leaves conditioned in a stream of Mata Atlântica than in Cerrado stream. The results showed that Phylloicus sp., had presented preference for food detritus of the Mata Antlântica biome and rejection to the one from Cerrado biome.
A scattering model for forested area
NASA Technical Reports Server (NTRS)
Karam, M. A.; Fung, A. K.
1988-01-01
A forested area is modeled as a volume of randomly oriented and distributed disc-shaped, or needle-shaped leaves shading a distribution of branches modeled as randomly oriented finite-length, dielectric cylinders above an irregular soil surface. Since the radii of branches have a wide range of sizes, the model only requires the length of a branch to be large compared with its radius which may be any size relative to the incident wavelength. In addition, the model also assumes the thickness of a disc-shaped leaf or the radius of a needle-shaped leaf is much smaller than the electromagnetic wavelength. The scattering phase matrices for disc, needle, and cylinder are developed in terms of the scattering amplitudes of the corresponding fields which are computed by the forward scattering theorem. These quantities along with the Kirchoff scattering model for a randomly rough surface are used in the standard radiative transfer formulation to compute the backscattering coefficient. Numerical illustrations for the backscattering coefficient are given as a function of the shading factor, incidence angle, leaf orientation distribution, branch orientation distribution, and the number density of leaves. Also illustrated are the properties of the extinction coefficient as a function of leaf and branch orientation distributions. Comparisons are made with measured backscattering coefficients from forested areas reported in the literature.
Antipredator behaviours of a spider mite in response to cues of dangerous and harmless predators.
Dias, Cleide Rosa; Bernardo, Ana Maria Guimarães; Mencalha, Jussara; Freitas, Caelum Woods Carvalho; Sarmento, Renato Almeida; Pallini, Angelo; Janssen, Arne
2016-07-01
Prey are known to invest in costly antipredator behaviour when perceiving cues of dangerous, but not of relatively harmless predators. Whereas most studies investigate one type of antipredator behaviour, we studied several types (changes in oviposition, in escape and avoidance behaviour) in the spider mite Tetranychus evansi in response to cues from two predatory mites. The predator Phytoseiulus longipes is considered a dangerous predator for T. evansi, whereas Phytoseiulus macropilis has a low predation rate on this prey, thus is a much less dangerous predator. Spider mite females oviposited less on leaf disc halves with predator cues than on clean disc halves, independent of the predator species. On entire leaf discs, they laid fewer eggs in the presence of cues of the dangerous predator than on clean discs, but not in the presence of cues of the harmless predator. Furthermore, the spider mites escaped more often from discs with cues of the dangerous predator than from discs without predator cues, but they did not escape more from discs with cues of the harmless predator. The spider mites did not avoid plants with conspecifics and predators. We conclude that the spider mites displayed several different antipredator responses to the same predator species, and that some of these antipredator responses were stronger with cues of dangerous predators than with cues of harmless predators.
Antibacterial and antioxidant activities of Vaccinium corymbosum L. leaf extract
Pervin, Mehnaz; Hasnat, Md Abul; Lim, Beong Ou
2013-01-01
Objective To investigate antibacterial and antioxidant activity of the leaf extract of tropical medicinal herb and food plant Vaccinium corymbosum L. (V. corymbosum). Methods Free radical scavenging activity on DPPH, ABTS, and nitrites were used to analyse phenoic and flavonoid contents of leaf extract. Other focuses included the determination of antioxidant enzymatic activity (SOD, CAT and GPx), metal chelating activity, reduction power, lipid peroxidation inhibition and the prevention of oxidative DNA damage. Antibacterial activity was determined by using disc diffusion for seven strains of bacteria. Results Results found that V. corymbosum leaf extract had significant antibacterial activity. The tested extract displayed the highest activity (about 23.18 mm inhibition zone) against Salmonella typhymurium and the lowest antibacterial activity was observed against Enterococcus faecalis (about 14.08 mm inhibition zone) at 10 mg/ disc. The IC50 values for DPPH, ABTS and radical scavenging activity were 0.120, 0.049 and 1.160 mg/mL, respectively. V. corymbosum leaf extract also showed dose dependent reduction power, lipid peroxidation, DNA damage prevention and significant antioxidant enzymatic activity. Conclusions These findings demonstrate that leaf extract of V. corymbosum could be used as an alternative therapy for antibiotic-resistant bacteria and help prevent various free radical related diseases.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Turgeon, R.; Wimmers, L.E.
1988-05-01
Vein loading of exogenous ({sup 14}C)sucrose was studied using short uptake and wash periods to distinguish between direct loading into veins and loading via mesophyll tissue. Mature leaf tissue of Pisum sativum L. cv Little Marvel, or Coleus blumei Benth. cv Candidum, was abraded and leaf discs were floated on ({sup 14}C)sucrose solution for 1 or 2 minutes. Discs were then washed for 1 to 30 min either at room temperature or in the cold and were frozen, lyophilized, and autoradiographed. In P. sativum, veins were clearly labeled after 1 minute uptake and 1 minute wash periods. Autoradiographic images didmore » not change appreciably with longer times of uptake or wash. Vein loading was inhibited by p-chloromercuribenzenesulfonic acid. These results indicate that uptake of exogenous sucrose occurs directly into the veins in this species. When C. blumei leaf discs were floated on ({sup 14}C)sucrose for 2 minutes and washed in the cold, the mesophyll was labeled but little, if any, minor vein loading occurred. When discs were labeled for 2 minutes and washed at room temperature, label was transferred from the mesophyll to the veins within minutes. These results indicate that there may be different patterns of phloem loading of photosynthetically derived sucrose in these two species.« less
Bennett, Jerry M.; Cortes, Peter M.
1985-01-01
The adsorption of water by thermocouple psychrometer assemblies is known to cause errors in the determination of water potential. Experiments were conducted to evaluate the effect of sample size and psychrometer chamber volume on measured water potentials of leaf discs, leaf segments, and sodium chloride solutions. Reasonable agreement was found between soybean (Glycine max L. Merr.) leaf water potentials measured on 5-millimeter radius leaf discs and large leaf segments. Results indicated that while errors due to adsorption may be significant when using small volumes of tissue, if sufficient tissue is used the errors are negligible. Because of the relationship between water potential and volume in plant tissue, the errors due to adsorption were larger with turgid tissue. Large psychrometers which were sealed into the sample chamber with latex tubing appeared to adsorb more water than those sealed with flexible plastic tubing. Estimates are provided of the amounts of water adsorbed by two different psychrometer assemblies and the amount of tissue sufficient for accurate measurements of leaf water potential with these assemblies. It is also demonstrated that water adsorption problems may have generated low water potential values which in prior studies have been attributed to large cut surface area to volume ratios. PMID:16664367
Bennett, J M; Cortes, P M
1985-09-01
The adsorption of water by thermocouple psychrometer assemblies is known to cause errors in the determination of water potential. Experiments were conducted to evaluate the effect of sample size and psychrometer chamber volume on measured water potentials of leaf discs, leaf segments, and sodium chloride solutions. Reasonable agreement was found between soybean (Glycine max L. Merr.) leaf water potentials measured on 5-millimeter radius leaf discs and large leaf segments. Results indicated that while errors due to adsorption may be significant when using small volumes of tissue, if sufficient tissue is used the errors are negligible. Because of the relationship between water potential and volume in plant tissue, the errors due to adsorption were larger with turgid tissue. Large psychrometers which were sealed into the sample chamber with latex tubing appeared to adsorb more water than those sealed with flexible plastic tubing. Estimates are provided of the amounts of water adsorbed by two different psychrometer assemblies and the amount of tissue sufficient for accurate measurements of leaf water potential with these assemblies. It is also demonstrated that water adsorption problems may have generated low water potential values which in prior studies have been attributed to large cut surface area to volume ratios.
Garber, M P
1977-05-01
The effects of chilling temperatures, in light or dark, on the isolated thylakoids and leaf discs of cucumber (Cucumis sativa L. "Marketer") and spinach (Spinacia oleracea L. "Bloomsdale") were studied. The pretreatment of isolated thylakoids and leaf discs at 4 C in the dark did not affect the phenazine methosulfate-dependent phosphorylation, proton uptake, osmotic response to sucrose, Ca(2+)-dependent ATPase activity, or chlorophyll content. Exposure of cucumber cotyledon discs and isolated thylakoids of cucumber and spinach to 4 C in light resulted in a rapid inactivation of the thylakoids. The sequence of activities or components lost during inactivation (starting with the most sensitive) are: phenazine methosulfate-dependent cyclic phosphorylation, proton uptake, osmotic response to sucrose, Ca(2+)-dependent ATPase activity, and chlorophyll. The rate of loss of proton uptake, osmotic response to sucrose, Ca(2+)-dependent ATPase activity and chlorophyll is similar for isolated cucumber and spinach thylakoids, whereas spinach thylakoids are more resistant to the loss of phenazine methosulfate-dependent phosphorylation. The thylakoids of spinach leaf discs were unaffected by exposure to 4 C in light. The results question whether the extreme resistance of spinach thylakoids treated in vivo is solely a function of the chloroplast thylakoid membranes and establish the validity of using in vitro results to make inferences about cucumber thylakoids treated in vivo at 4 C in light.
Garber, Melvin P.
1977-01-01
The effects of chilling temperatures, in light or dark, on the isolated thylakoids and leaf discs of cucumber (Cucumis sativa L. “Marketer”) and spinach (Spinacia oleracea L. “Bloomsdale”) were studied. The pretreatment of isolated thylakoids and leaf discs at 4 C in the dark did not affect the phenazine methosulfate-dependent phosphorylation, proton uptake, osmotic response to sucrose, Ca2+-dependent ATPase activity, or chlorophyll content. Exposure of cucumber cotyledon discs and isolated thylakoids of cucumber and spinach to 4 C in light resulted in a rapid inactivation of the thylakoids. The sequence of activities or components lost during inactivation (starting with the most sensitive) are: phenazine methosulfate-dependent cyclic phosphorylation, proton uptake, osmotic response to sucrose, Ca2+-dependent ATPase activity, and chlorophyll. The rate of loss of proton uptake, osmotic response to sucrose, Ca2+-dependent ATPase activity and chlorophyll is similar for isolated cucumber and spinach thylakoids, whereas spinach thylakoids are more resistant to the loss of phenazine methosulfate-dependent phosphorylation. The thylakoids of spinach leaf discs were unaffected by exposure to 4 C in light. The results question whether the extreme resistance of spinach thylakoids treated in vivo is solely a function of the chloroplast thylakoid membranes and establish the validity of using in vitro results to make inferences about cucumber thylakoids treated in vivo at 4 C in light. PMID:16659980
Microwave model prediction and verifications for vegetated terrain
NASA Technical Reports Server (NTRS)
Fung, A. K.
1985-01-01
To understand the scattering properties of a deciduous and a coniferous type vegetation scattering models were developed assuming either a disc type leaf or a needle type leaf. The major effort is to calculate the corresponding scattering phase functions and then each of the functions is used in a radiative transfer formulation to compute the scattering intensity and consequently the scattering coefficient. The radiative transfer formulation takes into account the irregular ground surface by including the rough soil surface in the boundary condition. Thus, the scattering model accounts for volume scattering inside the vegetation layer, the surface scattering from the ground and the interaction between scattering from the soil surface and the vegetation volume. The contribution to backscattering by each of the three scattering mechanisms is illustrated along with the effects of each layer or surface parameter. The major difference between the two types of vegetation is that when the incident wavelength is comparable to the size of the leaf there is a peak appearing in the mid angular region of the backscattering curve for the disc type leaf whereas it is a dip in the same region for a needle type leaf.
Maoz, Yonatan; Gal, Shira; Argov, Yael; Domeratzky, Sylvie; Coll, Moshe; Palevsky, Eric
2016-05-01
Antagonistic interactions among predators with shared prey are thought to hamper their ability to suppress herbivores. Our aim was to quantify intraguild interactions in omnivorous predatory mite assemblages in the presence of pollen, and assess their effect on pest populations. We focused on the following naturally occurring phytoseiid species in Israeli citrus orchards and their ability to suppress a key pest, the citrus rust mite (CRM) Phyllocoptruta oleivora (Eriophyidae): the generalists Amblyseius swirskii and Typhlodromus athiasae and the specialised pollen feeders Iphiseius degenerans, Euseius scutalis, E. stipulatus and E. victoriensis. Evaluations were performed on two spatial scales, tree seedlings and leaf discs. On seedlings, experiments were conducted to quantify the interactions between predators in the presence of pollen and its effects on CRM suppression. On leaf discs, intraguild interactions were studied between pairs of phytoseiid species in the presence of pollen without CRM. On seedlings, the specialised pollen predators were more effective at suppressing CRM populations than the generalist predators. In most cases, the more aggressive intraguild predator was the specialised pollen feeder. Similarly, leaf-disc experiments suggest that in these interactions the specialised pollen feeders tend to be the intraguild predators more often than the intraguild prey. © 2015 Society of Chemical Industry.
Influence of long-term low levels of ozone on the leaf surface mycoflora of pinto bean plants
DOE Office of Scientific and Technical Information (OSTI.GOV)
Manning, W.J.; Papia, P.M.
Pinto bean plants (Phaseols vulgaris strain 111) were grown for 4, 7, 14, 21, or 28 days in greenhouses containing ambient air charcoal-filtered air or ozone at 6 pphm for 8 hr/day. Ozone was produced with a Welbach generator and monitored with Mast meters. The upper and lower surfaces of the first set of simple true leaves were used to make leaf prints on acidified potato-dextrose agar plates (PDA) at each sampling period. Discs cut from these leaves were washed 10 times in sterile water and plated on PDA. Results with leaf prints showed that species of 25 genera ofmore » fungi were present in recognizable successions on all leaves. The number of fungi per cm/sup 2/ leaf tissue increased with leaf age for all leaves, with the greatest number occurring on 28-day-old leaves with accumulated ozone flecks. Differences between leaves by sources was more quantitative than qualitative, with the exception of Aspergillus niger, which was common only on the leaves of plants grown in ambient air. Botrytis cincrea was commonly found on plates printed with leaves that had ozone fleck. Isolates of Candida, Cryptococcus, and Penicillium were the most abundant fungi on all leaves. Similar results were obtained with plated washed leaf discs except that the number of fungi genera present was reduced from 25 to 11.« less
USDA-ARS?s Scientific Manuscript database
Phytophthora capsici is responsible for multiple disease syndromes of Capsicum annuum but the resistance mechanism is still unknown. Evaluating gene expression during foliar blight can be used to identify expression patterns associated with resistance in Capsicum species. This study reports a direct...
Brusselman, Eva; Beck, Bert; Pollet, Sabien; Temmerman, Femke; Spanoghe, Pieter; Moens, Maurice; Nuyttens, David
2012-10-01
Spray volume can influence the amount of free water on the leaf surface and subsequently the ability of entomopathogenic nematodes (EPNs) to move. In this study, an investigation was made of the effect of spray volume (548, 730 and 1095 L ha(-1) ) on the deposition, viability and infectivity of EPNs against Galleria mellonella on savoy cabbage, cauliflower and leek. Increasing spray volume decreased nematode deposition on 7.1 cm2 leek leaf discs at a 15° angle with the spray nozzle. Although the number of living nematodes observed on leek after 240 min of exposure was not significantly different between the low-volume application (548 L ha(-1) ) and the high-volume application (1095 L ha(-1) ), a greater infectivity was obtained in the latter application. The higher number of droplets deposited on the leek discs in the high-volume application may have stimulated nematode movement. No significant effect of spray volume was observed on the relative deposition of Steinernema carpocapsae on the bottom side of cauliflower and savoy cabbage leaf discs. In spite of the low S. carpocapsae deposition on the bottom side of the savoy cabbage discs, high infectivity was obtained against G. mellonella. Using the lowest spray volume on savoy cabbage, infectivity decreased with increasing exposure time, while infectivity was not affected by exposure time when a spray volume of 730 L ha(-1) or more was used. Spray volume is an important application parameter, as it affects nematode infectivity. Future research should investigate the effect of spray volume in the field and its influence on the effect of adjuvants. Copyright © 2012 Society of Chemical Industry.
Tong, Wen-Jie; Chen, Fu; Wen, Xin-Ya
2014-01-01
The absorption and accumulation of ten mineral elements in four kinds of organs (root, steam, leaf and flower disc) in Helianthus annuus L. plants cultured in Hetao Irrigation District under different level of salinity stress were determined by ICP-AES with wet digestion (HNO3 + HClO4). The results showed that: (1) The contents of Fe, Mn, Zn, Ca, and Na were highest in roots, so was K in stems, B and Mg in leaves and P in flower discs, while no significant difference was detected in the content of Cu among these organs; (2) The cumulants of Ca, Mg, P, Cu, B and Zn were highest in flower discs, so were Na, Fe and Mn in roots and K in stems; (3) In sunflower plants, the proportion of mineral element cumulant for K : Ca : Mg : P : Na was 16.71 : 5.23 : 3.86 : 1.23 : 1.00, and for Zn : Fe : B : Mn: Cu was 56.28 : 27.75 : 1.93 : 1.17 : 1.00, respectively; (4) The effect of salinity stress on absorption of mineral elements differed according to the kind of organ and element, root was the most sensitive to soil salt content, followed by stem and leaf, and the effect on flower disc seemed complex.
Canakçi, S
2003-01-01
The effects of 100, 250, and 500 ppm acetylsalicylic acid solutions treatments on weight alteration, pigment and protein amounts in discs from the primary leaves of one month old bean (Phaseolus vulgaris L.) seedlings produced tinder greenhouse conditions are presented. The experiments show that: 100 ppm ASA had no significant influence (P > 0.05) but 250 and 500 ppm ASA caused an increase on weight loss (P < 0.01); ASA at higher concentrations (250 and 500 ppm), generally, caused a decrease on pigment amounts (P < 0.05-P < 0.01) but 100 ppm ASA had no considerably significant influence on them (P > 0.05), none of the ASA treatments caused a statistically significant influence on carotenoid amount (P > 0.05); 100 and 250 ppm ASA treatments did not cause a significant influence on protein amount (P > 0.05). however 500 ppm ASA treatment caused an increase on protein injury (P < 0.05). Consequently, it is supposed that wet weight loss, pigment and protein injury have somewhat increased on leaf discs. depending on the toxic effect of high acetylsalicylic acid concentrations.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Vera, P.; Conejero, V.
The effect of ethephon (2-chloroetylphosphonic acid) on the degradation of proteins and on the induction of Lycopersicon esculentum pathogenesis-related (PR) proteins was studied in tomato leaf discs. The rate of ribulose, -1,5-bisphosphate carboxylase/oxygenase (Rubisco) degradation was maximal in discs after 48 hours of incubation with 1 millimolar ethephon, leading to complete disappearance of Rubisco after 96 hours. This effect was correlated with an increase in PR protein synthesis and the induction of the previously reported alkaline proteolytic enzyme PR-P69. In vivo pulse-chase experiments demonstrated that ethephon not only affected Rubisco content but that of many other {sup 35}S-labeled proteins asmore » well, indicating that ethylene activates a general and nonspecific mechanism of protein degradation. This effect was partially inhibited in vivo by the action of pCMB, a selective inhibitor of cysteine-proteinases such as P69. These data reinforce the hypothesis that P69 and perhaps other PR proteins are involved in the mechanism of accelerated protein degradation activated by ethylene.« less
Tabassum, Saira; Ahmed, Madiha; Mirza, Bushra; Naeem, Muhammad; Zia, Muhammad; Shanwari, Zabta Khan; Khan, Gul Majid
2017-03-09
The role of plants for discovery of therapeutic potential accentuates the need to know their biological attributes. The present study aims to comprehend the biological attributes of Rhus punjabensis, an unexplored traditional medicinal plant. Leaf and stem extracts of R. punjabensis prepared in 11 different organic solvents are evaluated for multimode antioxidant potential, total phenolic and flavonoid contents were determined through colorimetric assays, HPLC-DAD analysis was carried out for quantification of various polyphenols in extracts. Brine shrimp lethality, SRB and MTT assays were used to elucidate plant's cytotoxic and antileishmanial potentials. Disc diffusion assay was used to elucidate the protein kinase inhibitory, antibacterial and antifungal spectrum. Ethanol + ethyl acetate yielded maximum extract recovery from leaf (6.11 ± 1.09% w/w), total phenolic content (80.5 ± 2.18 μg GAE/mg extract) and reducing power potential (165.4 ± 2.29 μg AAE/mg extract). Maximum flavonoid content (30.50 ± 1.11 μg QE/mg extract) and highest DPPH based free radical scavenging activity (IC 50 11.4 ± 2.07) was exhibited by the methanol + chloroform leaf extract. The methanol extract showed maximum total antioxidant capacity (74.5 ± 2.25 μg AAE/mg DW), protein kinase inhibitory (12.5 ± 1.10 bald phenotype at 100 μg/disc) and antifungal (MIC = 25 μg/disc against Aspergillus flavus) potential. Reverse phase HPLC-DAD based quantification reveals presence of gallic acid, apigenin, rutin and catechin in various extracts. Brine shrimp lethality assay demonstrated most extracts as highly cytotoxic (LC 50 < 50 μg/mL) whereas chloroform extract of leaf demonstrated maximuminhibition against human leukemia cell line (IC 50 7.80 ± 0.01 μg/mL). A significant activity against leishmanial promastigotes was demonstrated by n-hexane leaf extract (IC 50 = 15.78 ± 0.15 μg/mL). A better antibacterial activity,by the extracts, against Gram positive strains as compared to Gram negative was observed. Results recommend multiple-solvent system as a critical factor to sumptuous the biological prospective of R. punjabensis and propose it to be a useful natural hub for the discovery of novel antioxidant, anticancer, antileishmanial and antimicrobial agents.
Keshavarz-Tohid, Vahid; Taheri, Parissa; Taghavi, Seyed Mohsen; Tarighi, Saeed
2016-07-20
Nitric oxide (NO) is one of the main signal molecules, which is involved in plant growth and development and can change regular physiological activity in biotic and abiotic stresses. In this study, the role of NO in induced resistance with Pseudomonas fluorescent (CHA0) and basal resistance against Rhizoctonia solani in bean plant was investigated. Our results revealed that P. fluorescent and R. solani can increase NO production at 6h post inoculation (hpi). Also, using the NO donor S-nitroso-N-acetyl D-penicillamine (SNAP) led to increase NO and bean plant resistance against R. solani. Utilizing the NO scavenger, 2-(4-carboxyphenyl)-4,4,5,5-tetramethy-limidazoline-1-oxyl-3-oxide (cPTIO), not only decreased basal resistance but also reduced induced resistance. In continue, the activity of antioxidant enzymes was studied in the former treatments. SNAP, CHA0 and R. solani increased the activity of peroxidase (POX), catalase (CAT) and ascorbate peroxidase (APX) at 6, 12 and 24h post inoculation (hpi). In contrast, using cPTIO and R. solani simultaneously (cPTIO+R) showed reduction in activity of POX and APX at 6 hpi. The cPTIO+R treatment increased POX, APX and CAT activity at 12 and 24 hpi. Hydrogen peroxide (H 2 O 2 ) monitoring in the leaf discs clarified that SNAP can increase H 2 O 2 production like CHA0 and R. solani. On the other hand, SNAP increased the resistance level of leaf discs against R. solani. Treating the leaf discs with cPTIO led to decrease resistance against the pathogen. These leaf discs showed reduction in H 2 O 2 production at 6 hpi and suddenly enhanced H 2 O 2 generation was observed at 24hpi. This study showed that CHA0 can increase NO level in bean plants. NO induced H 2 O 2 generation and regulated redox state of the host plant. This interaction resulted in significant defense against the pathogen. Copyright © 2016 Elsevier GmbH. All rights reserved.
Transfer cell wall ingrowths and vein loading characteristics in pea leaf discs. [Pisum sativum
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wimmers, L.E.; Turgeon, R.
1987-04-01
Transfer cell wall ingrowths are thought to increase transport capacity by increasing plasmalemma surface area. Leaf minor vein phloem transfer cells presumably enhance phloem loading. In Pisum sativum cv. Little marvel grown under different light regimes (150 to 1000 ..mu..mol photons m/sup -2/ sec/sup -1/) there is a positive correlation between light intensity and wall ingrowth area in phloem transfer cells. The extent of ingrowth and correlation to light intensity is greatest in minor veins, decreasing as vein size increases. Vein loading was assayed by floating abraded leaf discs on /sup 14/C-sucrose (10 mM). There is a positive correlation betweenmore » uptake and transfer cell wall area, although the latter increased more than the former. The difference in uptake is stable throughout the photoperiod, and is also stable in mature leaves for at least four days after plants are transfered to a different light intensity. Sucrose uptake is biphasic. The saturable component of uptake is sensitive to light intensity, the Km for sucrose is negatively correlated to light intensity, while V/sub max/remains unchanged.« less
Höfner, Roswitha; Vazquez-Moreno, Luz; Winter, Klaus; Bohnert, Hans J.; Schmitt, Jürgen M.
1987-01-01
Intact plants of the halophilic species Mesembryanthemum crystallinum were induced to exhibit Crassulacean acid metabolism by irrigation with nutrient solution containing 500 millimolar NaCl. During the induction period, the extractable activity of phosphoenolpyruvate carboxylase (PEPcase) increased approximately 40-fold. This increase was linearly correlated with a mass increase of PEPcase protein as measured by single radial immunodiffusion. De novo synthesis of PEPcase protein was shown by immunoprecipitation of the newly synthesized, radioactively labeled protein in leaf discs from salt-treated plants. Nontreated plants were characterized by a low level of the enzyme and low rates of PEPcase synthesis. Synthesis of this enzyme in leaf discs was correlated with the concentration of NaCl in the nutrient solution during growth. Images Fig. 1 Fig. 2 Fig. 3 PMID:16665363
Egger, Barbara; Spangl, Bernhard; Koschier, Elisabeth Helene
2016-01-01
Behavioural responses of Frankliniella occidentalis (Pergande) (Thysanoptera: Thripidae), a generalist, cell sap-feeding insect species with piercing-sucking mouthparts, after continuous exposure to two deterrent secondary plant compounds are investigated. We compared in choice assays on bean leaf discs, the settling, feeding, and oviposition preferences of F. occidentalis females that had no experience with the two fatty acid derivatives methyl jasmonate and cis-jasmone before testing (naïve thrips) vs. females that had been exposed to the deterrent compounds before testing (experienced thrips). The thrips were exposed to the deterrents at low or high concentrations for varied time periods and subsequently tested on bean leaf discs treated with the respective deterrent at either a low or a high concentration. Frankliniella occidentalis females avoided settling on the deterrent-treated bean leaf discs for an observation period of 6 h, independent of their previous experience. Our results demonstrate that feeding and oviposition deterrence of the jasmonates to the thrips were not altered by continuous exposure of the thrips to the jasmonates. Habituation was not induced, neither by exposure to the low concentration of the deterrents nor by exposure to the high concentration. These results indicate that the risk of habituation to two volatile deterrent compounds after repeated exposure is not evident in F. occidentalis. This makes the two compounds potential candidates to be integrated in pest management strategies. PMID:26726263
Egger, Barbara; Spangl, Bernhard; Koschier, Elisabeth Helene
2016-01-01
Behavioural responses of Frankliniella occidentalis (Pergande) (Thysanoptera: Thripidae), a generalist, cell sap-feeding insect species with piercing-sucking mouthparts, after continuous exposure to two deterrent secondary plant compounds are investigated. We compared in choice assays on bean leaf discs, the settling, feeding, and oviposition preferences of F. occidentalis females that had no experience with the two fatty acid derivatives methyl jasmonate and cis -jasmone before testing (naïve thrips) vs. females that had been exposed to the deterrent compounds before testing (experienced thrips). The thrips were exposed to the deterrents at low or high concentrations for varied time periods and subsequently tested on bean leaf discs treated with the respective deterrent at either a low or a high concentration. Frankliniella occidentalis females avoided settling on the deterrent-treated bean leaf discs for an observation period of 6 h, independent of their previous experience. Our results demonstrate that feeding and oviposition deterrence of the jasmonates to the thrips were not altered by continuous exposure of the thrips to the jasmonates. Habituation was not induced, neither by exposure to the low concentration of the deterrents nor by exposure to the high concentration. These results indicate that the risk of habituation to two volatile deterrent compounds after repeated exposure is not evident in F. occidentalis . This makes the two compounds potential candidates to be integrated in pest management strategies.
Thompson, N P
1976-01-01
Citrus leaf discs and fruit taken from trees sprayed at recommended levels and twice recommended levels with ethion, parathion, azinphosmethyl, carbophenothion, and dioxathion were shaken with water and wetting agent for removal of dislodgable residues at 0, 1, 3, 5, 7, 14 and 21 days following treatment. The first portion of the field experiment was performed during a period of no rainfall (April) and the second when there was rainfall (July) in 1973. Four replicates of 50 leaf discs and 4 fruit, respectively, were averaged from each sampling to give data reported. A gas chromatograph equipped with a flame photometric detector was used for analysis. Dislodgable residues found decreased with increasing time following application and samples from the wet period were lower than those from the dry period. Moisture and temperature could account for the differences in the two sampling period.
Gols, Rieta; Roosjen, Mara; Dijkman, Herman; Dicke, Marcel
2003-12-01
Jasmonic acid (JA) and the octadecanoid pathway are involved in both induced direct and induced indirect plant responses. In this study, the herbivorous mite, Tetranychus urticae, and its predator, Phytoseiulus persimilis, were given a choice between Lima bean plants induced by JA or spider mites and uninduced control plants. Infestation densities resulting in the induction of predator attractants were much lower than thus far assumed, i.e., predatory mites were significantly attracted to plants that were infested for 2 days with only one or four spider mites per plant. Phytoseiulus persimilis showed a density-dependent response to volatiles from plants that were infested with different numbers of spider mites. Similarly, treating plants with increasing concentrations of JA also led to increased attraction of P. persimilis. Moreover, the duration of spider mite infestation was positively correlated with the proportion of predators that were attracted to mite-infested plants. A pretreatment of the plants with JA followed by a spider mite infestation enhanced the attraction of P. persimilis to plant volatiles compared to attraction to volatiles from plants that were only infested with spider mites and did not receive a pretreatment with JA. The herbivore, T. urticae preferred leaf tissue that previously had been infested with conspecifics to uninfested leaf tissue. In the case of choice tests with JA-induced and control leaf tissue, spider mites slightly preferred control leaf tissue. When spider mites were given a choice between leaf discs induced by JA and leaf discs damaged by spider mite feeding, they preferred the latter. The presence of herbivore induced chemicals and/or spider mite products enhanced settlement of the mites, whereas treatment with JA seemed to impede settlement.
ERIC Educational Resources Information Center
School Science Review, 1979
1979-01-01
Included is information regarding: student construction of Newton's Discs to demonstrate color and of paper helicopters to encourage inquiry; improvising an apparatus demonstrating pressure between two bubbles; animal behavior experiments involving woodlice; two experiments using electronics freezer spray; chromatography of dyes; leaf keys; an…
Meir, S; Philosoph-Hadas, S; Epstein, E; Aharoni, N
1985-05-01
Various naturally occurring carbohydrates, applied at a concentration range of 1 to 100 mm, stimulated ethylene production for several days in indoleacetic acid (IAA)-treated or untreated tobacco (Nicotiana tabacum L. cv ;Xanthi') leaf discs. The lag period for this sugar-stimulated ethylene production was 8 to 12 hours after excision in the untreated leaf discs, but less than 2 hours in the IAA-treated ones. Among the tested carbohydrates, 12 were found to increase synergistically ethylene production, with d-galactose, sucrose, and lactose being the most active; mannitol and l-glucose had no effect. The extent and duration of the increased ethylene production was dependent upon the type of sugar applied, the tissue's age, and the existence of both exogenous IAA and sugar in the medium. Sucrose appeared to elicit a continuous IAA effect for 48 hours, as expressed by increased ethylene production, even when IAA was removed from the medium after a 4-hour pulse. Sucrose stimulated both the uptake and decarboxylation of [1-(14)C]IAA, as well as the hydrolysis of the esteric and amide IAA conjugates formed in the tissue after application of free IAA. This gradual hydrolysis was accompanied by a further accumulation of a third IAA metabolite. Moreover, synthetic indole-3-acetyl-l-alanine increased ethylene production mainly with sucrose, and this effect was accompanied by its increased decarboxylation and turnover pattern suggesting that release of free IAA was involved. An esteric IAA conjugate, tentatively identified by GC retention time was found to be the major component (84%) of the naturally occurring IAA conjugates in tobacco leaves. Accordingly the sucrose-stimulated ethylene production in tobacco leaves can be ascribed mainly to the sucrose-stimulated hydrolysis of the esteric IAA conjugate.
Gold leaf: From gilding to the fabrication of disposable, wearable and low-cost electrodes.
Santos, Mauro Sérgio Ferreira; Ameku, Wilson Akira; Gutz, Ivano Gebhardt Rolf; Paixão, Thiago Regis Longo Cesar
2018-03-01
Gold is among the most used materials in electrocatalysis. Despite this, this noble metal is still too expensive to be used in the fabrication of low cost and disposable devices. In the present work, gold-leaf sheets, usually employed in decorative crafts and wedding candies, is introduced as an inexpensive source of gold. Planar-disc and nanoband gold electrodes were simply and easily manufactured by combining gold leaf and polyimide tape. The planar disc electrode exhibited electrochemical behavior similar to that of a commercial gold electrode in 0.2molL -1 H 2 SO 4 ; cyclic voltammetry of a 1mmolL -1 solution of potassium ferricyanide (K 3 [Fe(CN) 6 ]) in 0.2molL -1 KNO 3 , using this novel electrode, displayed an 80mV difference between the oxidation and reduction peak potentials. The electrode also delivers promising prospects for the development of wearable devices. When submitted to severe mechanical deformation, this electrode exhibited neither loss of electrical contact nor significant variation in electrode response, even after fifteen bending and/or folding cycles. The thickness of the gold-leaf sheet facilitates the production of nanoband electrodes with behavior similar to that of ultramicroelectrodes. The electrode surface is easily renewed by cutting a thin slice off its end with a razor blade; this process led to limiting currents that were reproducible, presenting a relative standard deviation (RSD) of 3.8% (n = 5). Copyright © 2017 Elsevier B.V. All rights reserved.
Fungal composition on leaves explains pollutant-mediated indirect effects on amphipod feeding.
Bundschuh, Mirco; Zubrod, Jochen P; Kosol, Sujitra; Maltby, Lorraine; Stang, Christoph; Duester, Lars; Schulz, Ralf
2011-07-01
The energy stored in coarse particulate organic matter, e.g. leaf litter, is released to aquatic ecosystems by breakdown processes involving microorganisms and leaf shredding invertebrates. The palatability of leaves and thus the feeding of shredders on leaf material are highly influenced by microorganisms. However, implications in the colonization of leaves by microorganisms (=conditioning) caused by chemical stressors are rarely studied. Our laboratory experiments, therefore, investigated for the first time effects of a fungicide on the conditioning process of leaf material by means of food-choice experiments using Gammarus fossarum (Crustacea: Amphipoda). Additionally, microbial analyses were conducted to facilitate the mechanistic understanding of the observed behavior. Gammarids significantly preferred control leaf discs over those conditioned in presence of the fungicide tebuconazole at concentrations of 50 and 500 μg/L. Besides the decrease of fungal biomass with increasing fungicide concentration, also the leaf associated fungal community composition showed that species preferred by gammarids, such as Alatospora acumunata, Clavariopsis aquatica, or Flagellospora curvula, were more frequent in the control. Tetracladium marchalianum, however, which is rejected by gammarids, was abundant in all treatments suggesting an increasing importance of this species for the lower leaf palatability--as other more palatable fungal species were almost absent--in the fungicide treatments. Hence, the food-choice behavior of G. fossarum seems to be a suitable indicator for alterations in leaf associated microbial communities, especially fungal species composition, caused by chemical stressors. Finally, this or similar test systems may be a reasonable supplement to the environmental risk assessment of chemicals in order to achieve its protection goals, as on the one hand, indirect effects may occur far below concentrations known to affect gammarids directly, and on the other hand, the observed shifts in leaf associated microbial communities may have perpetuating implications in leaf shredding invertebrates. Copyright © 2011 Elsevier B.V. All rights reserved.
Effect of detergent on the quantification of grapevine downy mildew Sporangia from leaf discs
USDA-ARS?s Scientific Manuscript database
Grapevine downy mildew (DM), caused by the oomycete Plasmopara viticola (Berk. & Curt.) Berlese & de Toni, is a major disease, especially in humid viticultural areas. Development of resistant cultivars is an important objective for grapevine breeding. In order to establish a reliable and inexpensive...
Thermal stresses in the laser disc from a tetragonal c-cut crystal
NASA Astrophysics Data System (ADS)
Yumashev, K. V.; Loiko, P. A.
2014-12-01
Analytical expressions for thermal stresses and strains, as well as displacements, are obtained for the laser disc from a tetragonal crystal cut along the [0 0 1] axis under plane stress approximation, for the first time, to our knowledge. This study illustrates that, in polar coordinates, the normal stresses, σr and σθ, are angular independent, while the shear one τrθ is zero. The thermal strains, εr and εθ, and displacements, u and υ, depend on both radial and tangential coordinates; this dependence has the shape of a four-leaf rose. For considered crystal cutting with isotropic in-plane thermal expansion, the displacements are not pure radial (υ≠0). The values of stresses, strains and displacements are calculated for the disc from a c-cut yttrium vanadate laser crystal, Nd:YVO4. The thermal fracture issues are analyzed for this crystal.
Kasajima, Ichiro
2017-04-26
Oxidative stress is considered to be involved in growth retardation of plants when they are exposed to a variety of biotic and abiotic stresses. Despite its potential importance in improving crop production, comparative studies on oxidative stress tolerance between rice (Oryza sativa L.) cultivars are limited. This work describes the difference in term of oxidative stress tolerance between 72 rice cultivars. 72 rice cultivars grown under naturally lit greenhouse were used in this study. Excised leaf discs were subjected to a low concentration of methyl viologen (paraquat), a chemical reagent known to generate reactive oxygen species in chloroplast. Chlorophyll fluorescence analysis using a two-dimensional fluorescence meter, ion leakage analysis as well as the measurement of chlorophyll contents were used to evaluate the oxidative stress tolerance of leaf discs. Furthermore, fluorescence intensities were finely analyzed based on new fluorescence theories that we have optimized. Treatment of leaf discs with methyl viologen caused differential decrease of maximum quantum yield of photosystem II (Fv/Fm) between cultivars. Decrease of Fv/Fm was also closely correlated with increase of ion leakage and decrease of chlorophyll a/b ratio. Fv/Fm was factorized into photochemical and non-photochemical parameters to classify rice cultivars into sensitive and tolerant ones. Among the 72 compared rice cultivars, the traditional cultivar Co13 was identified as the most tolerant to oxidative stress. Koshihikari, a dominant modern Japonica cultivar in Japan as well as IR58, one of the modern Indica breeding lines exhibited a strong tolerance to oxidative stress. Close correlation between Fv/Fm and chlorophyll a/b ratio provides a simple method to estimate oxidative stress tolerance, without measurement of chlorophyll fluorescence with special equipment. The fact that modern cultivars, especially major cultivars possessed tolerance to oxidative stress suggests that oxidative stress tolerance is one of the agricultural traits prerequisite for improvement of modern rice cultivars. Data presented in this study would enable breeding of rice cultivars having strong tolerance to oxidative stress.
Using the conservative nature of fresh leaf surface density to measure foliar area
NASA Astrophysics Data System (ADS)
Castillo, Omar S.; Zaragoza, Esther M.; Alvarado, Carlos J.; Barrera, Maria G.; Dasgupta-Schubert, Nabanita
2014-10-01
For a herbaceous species, the inverse of the fresh leaf surface density, the Hughes constant, is nearly conserved. We apply the Hughes constant to develop an absolute method of leafarea measurement that requires no regression fits, prior calibrations or oven-drying. The Hughes constant was determined in situ using a known geometry and weights of a sub-set obtained from the fresh leaves whose areas are desired. Subsequently, the leaf-areas (at any desired stratification level), were derived by utilizing the Hughes constant and the masses of the fresh leaves. The proof of concept was established for leaf-discs of the plants Mandevilla splendens and Spathiphyllum wallisii. The conservativeness of the Hughes constant over individual leaf-zones and different leaftypes from the leaves of each species was quantitatively validated. Using the globally averaged Hughes constant for each species, the leaf-area of these and additional co-species plants, were obtained. The leaf-area-measurement-by-mass was cross-checked with standard digital image analysis. There were no statistically significant differences between the leaf-area-measurement-by-mass and the digital image analysis measured leaf-areas and the linear correlation between the two methods was very good. Leaf-areameasurement- by-mass was found to be rapid and simple with accuracies comparable to the digital image analysis method. The greatly reduced cost of leaf-area-measurement-by-mass could be beneficial for small agri-businesses in developing countries.
Ontogeny of the sheathing leaf base in maize (Zea mays).
Johnston, Robyn; Leiboff, Samuel; Scanlon, Michael J
2015-01-01
Leaves develop from the shoot apical meristem (SAM) via recruitment of leaf founder cells. Unlike eudicots, most monocot leaves display parallel venation and sheathing bases wherein the margins overlap the stem. Here we utilized computed tomography (CT) imaging, localization of PIN-FORMED1 (PIN1) auxin transport proteins, and in situ hybridization of leaf developmental transcripts to analyze the ontogeny of monocot leaf morphology in maize (Zea mays). CT imaging of whole-mounted shoot apices illustrates the plastochron-specific stages during initiation of the basal sheath margins from the tubular disc of insertion (DOI). PIN1 localizations identify basipetal auxin transport in the SAM L1 layer at the site of leaf initiation, a process that continues reiteratively during later recruitment of lateral leaf domains. Refinement of these auxin transport domains results in multiple, parallel provascular strands within the initiating primordium. By contrast, auxin is transported from the L2 toward the L1 at the developing margins of the leaf sheath. Transcripts involved in organ boundary formation and dorsiventral patterning accumulate within the DOI, preceding the outgrowth of the overlapping margins of the sheathing leaf base. We suggest a model wherein sheathing bases and parallel veins are both patterned via the extended recruitment of lateral maize leaf domains from the SAM. © 2014 The Authors. New Phytologist © 2014 New Phytologist Trust.
Kinetin Reversal of NaCl Effects
Katz, Adriana; Dehan, Klara; Itai, Chanan
1978-01-01
Leaf discs of Nicotiana rustica L. were floated on NaCl in the presence of kinetin or abscisic acid. On the 5th day 14CO2 fixation, [3H]leucine incorporation, stomatal conductance, and chlorophyll content were determined. Kinetin either partially or completely reversed the inhibitory effects of NaCl while ABA had no effect. PMID:16660618
Lyyra, Satu; Meagher, Richard B; Kim, Tehryung; Heaton, Andrew; Montello, Paul; Balish, Rebecca S; Merkle, Scott A
2007-03-01
Eastern cottonwood (Populus deltoides Bartr. ex Marsh.) trees were engineered to express merA (mercuric ion reductase) and merB (organomercury lyase) transgenes in order to be used for the phytoremediation of mercury-contaminated soils. Earlier studies with Arabidopsis thaliana and Nicotiana tabacum showed that this gene combination resulted in more efficient detoxification of organomercurial compounds than did merB alone, but neither species is optimal for long-term field applications. Leaf discs from in vitro-grown merA, nptII (neomycin phosphotransferase) transgenic cottonwood plantlets were inoculated with Agrobacterium tumefaciens strain C58 carrying the merB and hygromycin resistance (hptII) genes. Polymerase chain reaction of shoots regenerated from the leaf discs under selection indicated an overall transformation frequency of 20%. Western blotting of leaves showed that MerA and MerB proteins were produced. In vitro-grown merA/merB plants were highly resistant to phenylmercuric acetate, and detoxified organic mercury compounds two to three times more rapidly than did controls, as shown by mercury volatilization assay. This indicates that these cottonwood trees are reasonable candidates for the remediation of organomercury-contaminated sites.
Egger, Barbara; Koschier, Elisabeth H
2014-01-01
The larval stages of Frankliniella occidentalis Pergande (Thysanoptera: Thripidae) cause more direct feeding damage to plants than the adults. We, therefore, investigated the behaviour-modifying effects on second instar larvae of two jasmonic acid derivatives. The artificial application of methyl jasmonate and cis -jasmone, both at 1 % concentration, deterred the larvae from settling in a dual choice bean leaf disc assay. We observed a dose-dependent feeding deterrence of both jasmonates and calculated the concentration required to reduce the feeding damage by 50 % relative to the control treatment (FDC 50 ) for each jasmonate. The feeding damage was reduced by the application of cis -jasmone at 1 % concentration, but not by the jasmonates at the respective FDC 50 in no-choice leaf disc bioassays. However, significantly more larvae left jasmonate-treated whole potted bean plants by migrating to the soil compared with control plants. Our results may be exploited extending behavioural manipulation by using plant compounds in thrips control programmes to the full lifecycle of the pest. Plant compounds could be used in integrated and biological pest management strategies against F. occidentalis in combination with the application of various above and below ground control measures.
Effects of disc warping on the inclination evolution of star-disc-binary systems
NASA Astrophysics Data System (ADS)
Zanazzi, J. J.; Lai, Dong
2018-07-01
Several recent studies have suggested that circumstellar discs in young stellar binaries may be driven into misalignement with their host stars due to the secular gravitational interactions between the star, disc, and the binary companion. The disc in such systems is twisted/warped due to the gravitational torques from the oblate central star and the external companion. We calculate the disc warp profile, taking into account the bending wave propagation and viscosity in the disc. We show that for typical protostellar disc parameters, the disc warp is small, thereby justifying the `flat-disc' approximation adopted in previous theoretical studies. However, the viscous dissipation associated with the small disc warp/twist tends to drive the disc towards alignment with the binary or the central star. We calculate the relevant time-scales for the alignment. We find that the alignment is effective for sufficiently cold discs with strong external torques, especially for systems with rapidly rotating stars, but is ineffective for the majority of the star-disc-binary systems. Viscous warp-driven alignment may be necessary to account for the observed spin-orbit alignment in multiplanet systems if these systems are accompanied by an inclined binary companion.
NASA Astrophysics Data System (ADS)
Tommy, Lukas; Hardjianto, Mardi; Agani, Nazori
2017-04-01
Connect Four is a two-player game which the players take turns dropping discs into a grid to connect 4 of one’s own discs next to each other vertically, horizontally, or diagonally. At Connect Four, Computer requires artificial intelligence (AI) in order to play properly like human. There are many AI algorithms that can be implemented to Connect Four, but the suitable algorithms are unknown. The suitable algorithm means optimal in choosing move and its execution time is not slow at search depth which is deep enough. In this research, analysis and comparison between standard alpha beta (AB) Pruning and MTD(f) will be carried out at the prototype of Connect Four in terms of optimality (win percentage) and speed (execution time and the number of leaf nodes). Experiments are carried out by running computer versus computer mode with 12 different conditions, i.e. varied search depth (5 through 10) and who moves first. The percentage achieved by MTD(f) based on experiments is win 45,83%, lose 37,5% and draw 16,67%. In the experiments with search depth 8, MTD(f) execution time is 35, 19% faster and evaluate 56,27% fewer leaf nodes than AB Pruning. The results of this research are MTD(f) is as optimal as AB Pruning at Connect Four prototype, but MTD(f) on average is faster and evaluates fewer leaf nodes than AB Pruning. The execution time of MTD(f) is not slow and much faster than AB Pruning at search depth which is deep enough.
Pasupuleti, Visweswara Rao; Prasad, TNVKV; Shiekh, Rayees Ahmad; Balam, Satheesh Krishna; Narasimhulu, Ganapathi; Reddy, Cirandur Suresh; Rahman, Ismail Ab; Gan, Siew Hua
2013-01-01
Nanotechnology is gaining momentum due to its ability to transform metals into nanoparticles. The synthesis, characterization, and applications of biologically synthesized nanomaterials have become an important branch of nanotechnology. Plant extracts are a cost-effective, ecologically friendly, and efficient alternative for the large-scale synthesis of nanoparticles. In this study, silver nanoparticles (AgNps) were synthesized using Rhinacanthus nasutus leaf extract. After exposing the silver ions to the leaf extract, the rapid reduction of silver ions led to the formation of AgNps in solution. The synthesis was confirmed by ultraviolet-visible spectroscopy, Fourier transform infrared spectroscopy, and transmission electron microscopy. The in vitro antimicrobial activity of the AgNps synthesized using R. nasutus leaf extract was investigated against Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumonia, Escherichia coli, Aspergillus niger, and Aspergillus flavus using a disc diffusion method. The AgNps showed potential activity against all of the bacterial strains and fungal colonies, indicating that R. nasutus has the potential to be used in the development of value-added products in the biomedical and nanotechnology-based industries. PMID:24039419
Pasupuleti, Visweswara Rao; Prasad, T N V; Shiekh, Rayees Ahmad; Balam, Satheesh Krishna; Narasimhulu, Ganapathi; Reddy, Cirandur Suresh; Ab Rahman, Ismail; Gan, Siew Hua
2013-01-01
Nanotechnology is gaining momentum due to its ability to transform metals into nanoparticles. The synthesis, characterization, and applications of biologically synthesized nanomaterials have become an important branch of nanotechnology. Plant extracts are a cost-effective, ecologically friendly, and efficient alternative for the large-scale synthesis of nanoparticles. In this study, silver nanoparticles (AgNps) were synthesized using Rhinacanthus nasutus leaf extract. After exposing the silver ions to the leaf extract, the rapid reduction of silver ions led to the formation of AgNps in solution. The synthesis was confirmed by ultraviolet-visible spectroscopy, Fourier transform infrared spectroscopy, and transmission electron microscopy. The in vitro antimicrobial activity of the AgNps synthesized using R. nasutus leaf extract was investigated against Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumonia, Escherichia coli, Aspergillus niger, and Aspergillus flavus using a disc diffusion method. The AgNps showed potential activity against all of the bacterial strains and fungal colonies, indicating that R. nasutus has the potential to be used in the development of value-added products in the biomedical and nanotechnology-based industries.
C.M. Free; R.M. Landis; J. Grogan; M.D. Schulze; M. Lentini; O. Dunisch; NO-VALUE
2014-01-01
Knowledge of tree age-size relationships is essential towards evaluating the sustainability of harvest regulations that include minimum diameter cutting limits and fixed-length cutting cycles. Although many tropical trees form annual growth rings and can be aged from discs or cores, destructive sampling is not always an option for valuable or threatened species. We...
de Araujo, José M; Marques, Edmilson J; de Oliveira, José V
2009-01-01
This work aimed to determine the efficiency of the entomopathogenic fungi Metarhizium anisopliae and Beauveria bassiana to control the aphid Lipaphis erysimi (Kalt.) (Hemiptera: Aphididae) in kale Brassica oleracea var acephala D.C., as well as their compatibility with a neem oil formulation (Neemseto). Ten isolates of both fungi were tested and the most pathogenic ones were B. bassiana CG001 and M. anisopliae CG30 with 90% and 4.4 days, and 64% and 3.8 days of mortality and median lethal time, respectively. Bioassays with neem at concentrations of 0.5, 1.0 and 2.0% were done either by leaf discs dipping or spraying the aphids on the leaf discs. The neem spraying treatment at 2.0% provided 90% mortality. The use of B. bassiana isolate CG001 or M. anisopliae isolate CG30 with neem at 0.125, 0.25, and 0.5%, demonstrated that these isolates could have their spore viability or colony growth affected when exposed to neem concentrations higher than 0.25%. In absolute values, the isolates B. bassiana CG001 and M. anisopliae CG30 are the most virulent to L. erysimi, and could be utilized in the management of this pest.
Andralojc, P J; Keys, A J; Martindale, W; Dawson, G W; Parry, M A
1996-10-25
[1-14C]Hamamelose (2-hydroxymethyl-D-ribose) was synthesized by reaction of ribulose 5-phosphate with potassium [14C]cyanide, catalytic hydrogenation of the resulting cyanohydrin, and dephosphorylation of the product. Its identity was established by a chromatographic comparison with hamamelose isolated from the bark of witch hazel (Hamamelis virginiana L.). Following vacuum infiltration of the [1-14C]hamamelose into leaf discs from Phaseolus vulgaris L., 14C-labeled 2carboxy-D-arabinitol (CA) and 2-carboxy-D-arabinitol 1-phosphate (CA1P) were formed, in the dark. Conversion of hamamelose to both CA and CA1P in the leaf discs was inhibited by dithiothreitol and sodium fluoride, although at high concentrations of these inhibitors conversion into CA was still evident when conversion into CA1P was totally inhibited. Wheat (Triticum aestivum L.) leaves converted hamamelose into CA without formation of CA1P. Leaves from P. vulgaris contained 68 nmol.g-1 fresh weight of hamamelose in the light and 35 nmol.g-1 fresh weight in the dark. A pathway for the biosynthesis of CA1P from Calvin cycle intermediates is proposed which includes the sequence: hamamelose --> CA --> CA1P.
Effect of altered sink:source ratio on photosynthetic metabolism of source leaves
DOE Office of Scientific and Technical Information (OSTI.GOV)
Plaut, Z.; Mayoral, M.L.; Reinhold, L.
When seven crop species were grown under identical environmental conditions, decreased sink:source ratio led to a decreased photosynthetic rate within 1 to 3 days in Cucumis sativus L., Gossypium hirsutum L., and Raphanus sativus L., but not in Capsicum annuum L., Solanum melongena L., Phaseolus vulgaris L., or Ricinus communis L. The decrease was not associated with stomatal closure. In cotton and cucumbers, sink removal led to an increase in starch and sugar content, in glucose 6-phosphate and fructose 6-phosphate pools, and in the proportion of /sup 14/C detected in sugar phosphates and UDPglucose following /sup 14/CO/sub 2/ supply. Whenmore » mannose was supplied to leaf discs to sequester cytoplasmic inorganic phosphate, promotion of starch synthesis, and inhibition of CO/sub 2/ fixation, were observed in control discs, but not in discs from treated plants. Phosphate buffer reduced starch synthesis in the latter, but not the former discs. The findings suggest that sink removal led to a decreased ratio inorganic phosphate:phosphorylated compounds. In beans /sup 14/C in sugar phosphates increased following sink removal, but without sucrose accumulation, suggesting tighter feedback control of sugar level. Starch accumulated to higher levels than in the other plants, but CO/sub 2/ fixation rate was constant for several days.« less
Regassa, Fekadu; Araya, Mengistu
2012-08-01
Following the rapidly expanding dairy enterprise, mastitis has remained the most economically damaging disease. The objective of this study was mainly to investigate the in vitro antibacterial activities of ethanol extracts of Combretum molle (R.Br.Ex.G.Don) Engl & Diels (Combretaceae) against antibiotic-resistant and susceptible Staphylococcus aureus and Streptococcus agalactiae isolated from clinical cases of bovine mastitis using agar disc diffusion method. The leaf and bark extracts showed antibacterial activity against S. aureus at concentrations of 3 mg/ml while the stem and seed extract did not show any bioactivity. Although both leaf and bark extracts were handled in the same manner, the antibacterial activity of the bark extract against the bacterial strains had declined gradually to a lower level as time advanced after extraction. The leaf extract had sustained bioactivity for longer duration. The susceptibility of the bacteria to the leaf extract is not obviously different between S. aureus and S. agalactiae. Also, there was no difference in susceptibility to the leaf extract between the antibiotic-resistant and antibiotic-sensitive bacteria. Further phytochemical and in vivo efficacy and safety studies are required to evaluate the therapeutic value of the plant against bovine mastitis.
NASA Astrophysics Data System (ADS)
Rita, Wiwik Susanah; Swantara, I. Made Dira; Asih, I. A. Raka Astiti; Sinarsih, Ni Ketut; Suteja, I. Kadek Pater
2016-03-01
Total flavonoid and phenolic contents in some natural products was suspected of having a positive correlation to its activity in inhibiting the growth of bacteria. The aim of this study was to determine the total flavonoid and phenolic contents of n-butanol extract of Samanea saman leaf, and to evaluate the antibacterial activity towards Escherechia coli and Staphylococcus aureus. Extraction of compounds was done by ethanol 96%, followed by fractionation into n-hexane, ethyl acetate, and n-butanol. Determination of total flavonoid and phenolic contents was done by UV-Vis Spectrophotometer using standard of quersetin and galic acid respectively. In addition, antibacterial activity was evaluated by agar disc diffusion method. Extraction of 1000 g of Samanea saman leaf was obtained 80 g of ethanol extracts, fractionation of the extract was obtained 8.02 g of n-hexane extracts, 7.11 g of ethyl acetate extracts, 13.5 g of n-butanol extracts, and 14.16 g of aqueous extracts. Phytochemical screening of the n-butanol extracts revealed the presence of flavonoid and phenolic compounds. Total flavonoid and phenolic contents were successively 43.5798 mg QE/100g and 34.0180 mg GAE/100g. The butanol extracts inhibited the growth of S.aureus higher than the growth of E.coli. At the concentration of 2, 4, 6, 8 % (b/v), and positive control (meropenem μg/disc), inhibition zone towards S. aureus was successively 5.67, 9.33, 10.33, 12.00, and 32.33 mm, while the inhibition zone towards E. coli was1.33, 3.33, 4.33, 5.43, and 34.00 mm.
NASA Astrophysics Data System (ADS)
Ajitha, B.; Ashok Kumar Reddy, Y.; Sreedhara Reddy, P.
2014-07-01
This study reports the simple green synthesis method for the preparation of silver nanoparticles (Ag NPs) using Plectranthus amboinicus leaf extract. The pathway of nanoparticles formation is by means of reduction of AgNO3 by leaf extract, which acts as both reducing and capping agents. Synthesized Ag NPs were subjected to different characterizations for studying the structural, chemical, morphological, optical and antimicrobial properties. The bright circular fringes in SAED pattern and diffraction peaks in XRD profile reveals high crystalline nature of biosynthesized Ag NPs. Morphological studies shows the formation of nearly spherical nanoparticles. FTIR spectrum confirms the existence of various functional groups of biomolecules capping the nanoparticles. UV-visible spectrum displays single SPR band at 428 nm indicating the absence of anisotropic particles. The synthesized Ag NPs exhibited better antimicrobial property towards gram negative Escherichia coli and towards tested Penicillium spp. than other tested microorganisms using disc diffusion method. Finally it has proven that the synthesized bio-inspired Ag NPs have potent antimicrobial effect.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Casale, W.L.
1987-01-01
The 12,13-epoxytrichothecene mycotoxins deoxynivalenol (DON, vomitoxin) and T-2 toxin inhibited protein synthesis in vivo and in cell-free systems from wheat and maize, host plants of trichothecene-producing Fusarium spp.Protein synthesis in tissue (leaf discs and kernel sections) was measured by incorporation of /sup 3/H-leucine into acetone:ethanol insoluble material, and in cell-free translation systems from wheat embryos and maize seedling plumules by incorporation of /sup 3/H-leucine into trichloroacetic acid-insoluble material. The toxin concentration inhibiting 50% of /sup 3/H-leucine incorporation (ID/sub 50/) by several maize varieties were 0.9 ..mu..M (T-2 toxin) and 9-22 ..mu..M (DON). ID/sub 50/ values for wheat were 0.25 ..mu..Mmore » (T-2 toxin) and 4.5 ..mu..M (DON).« less
USDA-ARS?s Scientific Manuscript database
Transgenic plants of tobacco (Nicotiana tabacum L) and plum (Prunus domestica L) were produced by transforming with apple class 1 KNOX genes (MdKN1 and MdKN2) or corn KN1 gene. Transgenic tobacco plants were regenerated in vitro from transformed leaf discs cultured in a tissue medium lacking cytoki...
Vital, Pierangeli G; Rivera, Windell L
2011-10-01
To determine the antibacterial, antifungal, antiprotozoal, cytotoxic, and phytochemical properties of ethanol extracts of leaves of Voacanga globosa (Blanco) Merr. (V. globosa). The extracts were tested against bacteria and fungus through disc diffusion assay; against protozoa through growth curve determination, antiprotozoal and cytotoxicity assays. The extract revealed antibacterial activities, inhibiting the growth of Staphylococcus aureus, Bacillus cereus, Pseudomonas aeruginosa, Micrococcus luteus, and Salmonella typhimurium. Antifungal assay showed that it inhibited Candida albicans. The antiprotozoal assay against Trichomonas vaginalis and Entamoeba histolytica showed that V. globosa can inhibit the parasites, wherein the action can be comparable to metronidazole. With the in situ cell death detection kit, Trichomonas vaginalis and Entamoeba histolytica exposed to V. globosa leaf extract was observed to fluoresce simultaneously in red and yellow signals signifying apoptotic-like changes. Preliminary phytochemical screening revealed the chemical composition of plant extract containing alkaloids, saponins, 2-deoxysugars, and hydrolysable tannins. Thus, this study provides scientific evidence on the traditional use of V. globosa leaf extract in treating microbial diseases. Further, the leaf extract can possibly be used to produce alternative forms of antimicrobials. Copyright © 2011 Hainan Medical College. Published by Elsevier B.V. All rights reserved.
Fisher, K; Rowe, C; Phillips, C A
2007-05-01
To test the effect of oils and vapours of lemon, sweet orange and bergamot and their components against three Arcobacter butzleri strains. The disc diffusion method was used to screen the oils and vapours against three strains of A. butzleri. In vitro bergamot was the most inhibitory essential oil (EO) and both citral and linalool were effective. On cabbage leaf, the water isolate was the least susceptible to bergamot EO, citral and linalool (1-2 log reduction), with the chicken isolate being the most susceptible (6-8 log reduction). However, the latter appeared not to be susceptible to vapours over 24 h although type strain and water isolate populations reduced by 8 logs. On chicken skin, the effectiveness of the oils was reduced compared with that on cabbage leaf. Bergamot was the most effective of the oils tested and linalool the most effective component. All strains tested were less susceptible in food systems than in vitro. Arcobacter isolates vary in their response to EO suggesting that the results of type strain studies should be interpreted with caution. Bergamot EO has the potential for the inhibition of this 'emerging' pathogen.
Terminalia ferdinandiana Exell. Extracts inhibit the growth of body odour-forming bacteria.
McManus, K; Wood, A; Wright, M H; Matthews, B; Greene, A C; Cock, I E
2017-10-01
Terminalia ferdinandiana extracts are potent growth inhibitors of many bacterial pathogens. They may also inhibit the growth of malodour-producing bacteria and thus be useful deodorant components, although this is yet to be tested. Terminalia ferdinandiana fruit and leaf solvent extracts were investigated by disc diffusion and liquid dilution MIC assays against the most significant bacterial contributors to axillary and plantar malodour formation. Toxicity was determined using the Artemia franciscana nauplii bioassay. Non-targeted HPLC separation of the methanolic leaf extract coupled to high-resolution time-of-flight (TOF) mass spectroscopy was used for the identification and characterization of individual components in the extract. The T. ferdinandiana leaf extracts were the most potent bacterial growth inhibitors. The leaf methanolic extract was particularly potent, with low MIC values against C. jeikeium (233 μg mL -1 ), S. epidermidis (220 μg mL -1 ), P. acnes (625 μg mL -1 ) and B. linens (523 μg mL -1 ). The aqueous and ethyl acetate leaf extracts were also potent growth inhibitors of C. jeikeium and S. epidermidis (MICs < 1000 μg mL -1 ). In comparison, the fruit extracts were substantially less potent antibacterial agents, although still with MIC values indicative of moderate growth inhibitory activity. All T. ferdinandiana leaf extracts were non-toxic in the Artemia franciscana bioassay. Non-biased phytochemical analysis of the methanolic leaf extract revealed the presence of high levels of and high diversity of tannins and high levels of the flavone luteolin. The low toxicity of the T. ferdinandiana leaf extracts and their potent growth inhibition of axillary and plantar malodour-producing bacteria indicate their potential as deodorant components. © 2017 Society of Cosmetic Scientists and the Société Française de Cosmétologie.
Zhang, Zi-Shan; Liu, Mei-Jun; Gao, Hui-Yuan; Jin, Li-Qiao; Li, Yu-Ting; Li, Qing-Ming; Ai, Xi-Zhen
2015-10-16
Although root-to-shoot communication has been intensively investigated in plants under drought, few studies have examined root-to-shoot communication under chilling. Here we explored whether root-to-shoot communication contributes to the chilling-light tolerance of cucumber shoots and clarified the key signal involves in this communication. After leaf discs chilling-light treatment, the photoinhibitions of Photosystem I (PSI) and Photosystem II (PSII) were similar in leaf discs of two cucumber varieties (JY-3 and JC-4). When the whole plants, including roots, were chilled under light, the photosynthetic performances in JC-4 leaves decreased more seriously than that in JY-3 leaves. However, when the water status of leaves was maintained by warming roots or floating the attached leaves on water, the PSII activity and amount of PSI in the leaves of the two varieties were similar after chilling-light treatment. In addition, the differences of PSII activities and amount of PSI between the two varieties under whole plant chilling-light treatment were independent of ABA pretreatment. Above results indicate that (1) the better water status in leaves under chilling contributes to the higher chilling tolerance of JY-3; (2) the water status, rather than an ABA signal, dominates root-to-shoot communication under chilling and the chilling tolerance of cucumber shoot.
Bajpai, Vivek K; Al-Reza, Sharif M; Choi, Ung Kyu; Lee, Jong Hwi; Kang, Sun Chul
2009-08-01
The aims of this study were to analyze the chemical composition of leaf essential oil of Metasequioa glyptostroboides Miki, and to test the efficacy of oil and extracts (hexane, chloroform, ethyl acetate and methanol) against food spoilage and food-borne pathogenic bacteria and their antioxidant activity. The GC-MS analysis revealed 49 compounds representing 94.62% of the total oil containing 2-butaneone (30.6%), cyclopentane (15.1%), beta-myrcene (13.29%), cyclobutane (7.67%), furan (3%), valeramide (2.81%), borneol (1.2%), beta-farnesene (1.67%), thymol (1.44%) and alpha-pinene (1.46%) as major components. The oil (1000 microg/disc), and extracts (1500 microg/disc) exhibited promising antibacterial effect as a diameter of zones of inhibition (10-18 and 7-13 mm), respectively. MIC values of oil and the extracts were ranged 125-2000 and 250 to <2000 microg/ml, respectively. Also the oil had strong antibacterial effect on the viable counts. Scanning electron microscopic study demonstrated potential detrimental effect of the oil on the morphology of S. aureus KCTC1916. The free radical scavenging activities of the oil and ethyl acetate extract were found to be 11.32 and 19.12 microg/ml, respectively. Also the ethyl acetate extract revealed the highest phenolic contents (85.17 mg/g of dry wt) as compared to the other extracts.
NASA Technical Reports Server (NTRS)
Van Volkenburgh, E.; Cleland, R. E.
1990-01-01
Cell expansion in dicotyledonous leaves is strongly stimulated by bright white light (WL), at least in part as a result of light-induced acidification of the cell walls. It has been proposed that photosynthetic reactions are required for light-stimulated transport processes across plasma membranes of leaf cells, including proton excretion. The involvement of photosynthesis in growth and wall acidification of primary leaves of bean has been tested by inhibiting photosynthesis in two ways: by reducing chlorophyll content of intact plants with tentoxin (TX) and by treating leaf discs with 3-(3,4-dichlorophenyl)-1,1-dimethylurea (DCMU). Exposure to bright WL stimulated growth of intact leaves of TX-treated plants. Discs excised from green as well as from TX-or DCMU-treated leaves also responded by growing faster in WL, as long as exogenous sucrose was supplied to the photosynthetically inhibited tissues. The WL caused acidification of the epidermal surface of intact TX-leaves, but acidification of the incubation medium by mesophyll cells only occurred when photosynthesis was not inhibited. It is concluded that light-stimulated cell enlargement of bean leaves, and the necessary acidification of epidermal cell walls, are mediated by a pigment other than chlorophyll. Light-induced proton excretion by mesophyll cells, on the other hand, may require both a photosynthetic product (or exogenous sugars) and a non-photosynthetic light effect.
Phyllanthus wightianus Müll. Arg.: A Potential Source for Natural Antimicrobial Agents
Natarajan, D.; Srinivasan, R.; Shivakumar, M. S.
2014-01-01
Phyllanthus wightianus belongs to Euphorbiaceae family having ethnobotanical importance. The present study deals with validating the antimicrobial potential of solvent leaf extracts of P. wightianus. 11 human bacterial pathogens (Bacillus subtilis, Streptococcus pneumoniae, Staphylococcus epidermidis, Proteus vulgaris, Pseudomonas aeruginosa, Klebsiella pneumoniae, Salmonella typhimurium, Escherichia coli, Shigella flexneri, Proteus vulgaris, and Serratia marcescens) and 4 fungal pathogens (Candida albicans, Cryptococcus neoformans, Mucor racemosus, and Aspergillus niger) were also challenged with solvent leaf extracts usingagar well and disc diffusion methods. Further, identification of the active component present in the bioactive extract was done using GC-MS analysis. Results show that all extracts exhibited broad spectrum (6–29 mm) of antibacterial activity on most of the tested organisms. The results highlight the fact that the well in agar method was more effective than disc diffusion method. Significant antimicrobial activity was detected in methanol extract against S. pneumoniae (29 mm) with MIC and MBC values of 15.62 μg/mL. GC-MS analysis revealed that 29 bioactive constituents were present in methanolic extract of P. wightianus, of which 9,12-octadecaenioic acid (peak area 22.82%; RT-23.97) and N-hexadecanoic acid (peak area 21.55% RT-21.796) are the major compounds. The findings of this study show that P. wightianus extracts may be used as an anti-infective agent in folklore medicine. PMID:24883301
Non-reclosing pressure relief device for vacuum systems
Swansiger, William A.
1994-01-01
A non-reclosing overpressure protection device such as a rupture disc provides a non-reclosing opening upon forcible contact with a knife blade. A bellows, having an inlet capable of being sealably connected to a source of pressure (the vacuum system) and an outlet containing the rupture disc, transmits the pressure in the system to the disc. The bellows maintains the disc away from the knife when the pressure is below an overpressure amount, and carries the disc to a position when the pressure is above an overpressure amount where the disc is ruptured by the knife.
Non-reclosing pressure relief device for vacuum systems
Swansiger, W.A.
1994-02-08
A non-reclosing overpressure protection device such as a rupture disc provides a non-reclosing opening upon forcible contact with a knife blade. A bellows, having an inlet capable of being sealably connected to a source of pressure (the vacuum system) and an outlet containing the rupture disc, transmits the pressure in the system to the disc. The bellows maintains the disc away from the knife when the pressure is below an overpressure amount, and carries the disc to a position when the pressure is above an overpressure amount where the disc is ruptured by the knife. 6 figures.
Joseph, Karunan; Ibrahim, Fatimah; Cho, Jongman
2015-01-01
Recent advances in the field of centrifugal microfluidic disc suggest the need for electrical interface in the disc to perform active biomedical assays. In this paper, we have demonstrated an active application powered by the energy harvested from the rotation of the centrifugal microfluidic disc. A novel integration of power harvester disc onto centrifugal microfluidic disc to perform localized heating technique is the main idea of our paper. The power harvester disc utilizing electromagnetic induction mechanism generates electrical energy from the rotation of the disc. This contributes to the heat generation by the embedded heater on the localized heating disc. The main characteristic observed in our experiment is the heating pattern in relative to the rotation of the disc. The heating pattern is monitored wirelessly with a digital temperature sensing system also embedded on the disc. Maximum temperature achieved is 82 °C at rotational speed of 2000 RPM. The technique proves to be effective for continuous heating without the need to stop the centrifugal motion of the disc.
NASA Astrophysics Data System (ADS)
Dogan, Suzan
2016-07-01
Accretion discs are common in binary systems, and they are often found to be misaligned with respect to the binary orbit. The gravitational torque from a companion induces nodal precession in misaligned disc orbits. In this study, we first calculate whether this precession is strong enough to overcome the internal disc torques communicating angular momentum. We compare the disc precession torque with the disc viscous torque to determine whether the disc should warp or break. For typical parameters precession wins: the disc breaks into distinct planes that precess effectively independently. To check our analytical findings, we perform 3D hydrodynamical numerical simulations using the PHANTOM smoothed particle hydrodynamics code, and confirm that disc breaking is widespread and enhances accretion on to the central object. For some inclinations, the disc goes through strong Kozai cycles. Disc breaking promotes markedly enhanced and variable accretion and potentially produces high-energy particles or radiation through shocks. This would have significant implications for all binary systems: e.g. accretion outbursts in X-ray binaries and fuelling supermassive black hole (SMBH) binaries. The behaviour we have discussed in this work is relevant to a variety of astrophysical systems, for example X-ray binaries, where the disc plane may be tilted by radiation warping, SMBH binaries, where accretion of misaligned gas can create effectively random inclinations and protostellar binaries, where a disc may be misaligned by a variety of effects such as binary capture/exchange, accretion after binary formation.
On the formation of planetary systems in photoevaporating transition discs
NASA Astrophysics Data System (ADS)
Terquem, Caroline
2017-01-01
In protoplanetary discs, planetary cores must be at least 0.1 M⊕ at 1 au for migration to be significant; this mass rises to 1 M⊕ at 5 au. Planet formation models indicate that these cores form on million year time-scales. We report here a study of the evolution of 0.1 and 1 M⊕ cores, migrating from about 2 and 5 au, respectively, in million year old photoevaporating discs. In such a disc, a gap opens up at around 2 au after a few million years. The inner region subsequently accrete on to the star on a smaller time-scale. We find that, typically, the smallest cores form systems of non-resonant planets beyond 0.5 au with masses up to about 1.5 M⊕. In low-mass discs, the same cores may evolve in situ. More massive cores form systems of a few Earth-mass planets. They migrate within the inner edge of the disc gap only in the most massive discs. Delivery of material to the inner parts of the disc ceases with opening of the gap. Interestingly, when the heavy cores do not migrate significantly, the type of systems that are produced resembles our Solar system. This study suggests that low-mm flux transition discs may not form systems of planets on short orbits but may instead harbour Earth-mass planets in the habitable zone.
Choi, K W; Han, O; Lee, H J; Yun, Y C; Moon, Y H; Kim, M; Kuk, Y I; Han, S U; Guh, J O
1998-01-01
In an effort to develop transgenic plants resistant to diphenyl ether herbicides, we introduced the protoporphyrinogen oxidase (EC 1.3.3.4) gene of Bacillus subtilis into tobacco plants. The results from a Northern analysis and leaf disc assay indicate that the expression of the B. subtilis protoporphyrinogen oxidase gene under the cauliflower mosaic virus 35S promoter generated resistance to the diphenyl ether herbicide, oxyfluorfen, in transgenic tobacco plants.
NASA Astrophysics Data System (ADS)
Martin, Rebecca G.; Lubow, Stephen H.
2018-06-01
In a recent paper Martin & Lubow showed that a circumbinary disc around an eccentric binary can undergo damped nodal oscillations that lead to the polar (perpendicular) alignment of the disc relative to the binary orbit. The disc angular momentum vector aligns to the eccentricity vector of the binary. We explore the robustness of this mechanism for a low mass disc (0.001 of the binary mass) and its dependence on system parameters by means of hydrodynamic disc simulations. We describe how the evolution depends upon the disc viscosity, temperature, size, binary mass ratio, orbital eccentricity and inclination. We compare results with predictions of linear theory. We show that polar alignment of a low mass disc may occur over a wide range of binary-disc parameters. We discuss the application of our results to the formation of planetary systems around eccentric binary stars.
NASA Astrophysics Data System (ADS)
Ajitha, B.; Ashok Kumar Reddy, Y.; Reddy, P. Sreedhara
2014-03-01
In this paper we report the green synthesis of silver nanoparticles (Ag NPs) using Tephrosia purpurea leaf extract. The biomolecules present in the leaf extract are responsible for the formation of Ag NPs and they found to play dual role of both reducing as well as capping agents. The high crystallinity of Ag NPs is evident from bright circular spot array of SAED pattern and diffraction peaks in XRD profile. The synthesized Ag NPs are found to be nearly spherical ones with size approximately ∼20 nm. FTIR spectrum evidences the presence of different functional groups of biomolecules participated in encapsulating Ag NPs and the possible mechanism of Ag NPs formation was also suggested. Appearance of yellow color and surface plasmon resonance (SPR) peak at 425 nm confirms the Ag NPs formation. PL spectra showed decrement in luminescence intensity at higher excitation wavelengths. Antimicrobial activity of Ag NPs showed better inhibitory activity towards Pseudomonas spp. and Penicillium spp. compared to other test pathogens using standard Kirby-Bauer disc diffusion assay.
Ajitha, B; Ashok Kumar Reddy, Y; Sreedhara Reddy, P
2014-07-15
This study reports the simple green synthesis method for the preparation of silver nanoparticles (Ag NPs) using Plectranthus amboinicus leaf extract. The pathway of nanoparticles formation is by means of reduction of AgNO3 by leaf extract, which acts as both reducing and capping agents. Synthesized Ag NPs were subjected to different characterizations for studying the structural, chemical, morphological, optical and antimicrobial properties. The bright circular fringes in SAED pattern and diffraction peaks in XRD profile reveals high crystalline nature of biosynthesized Ag NPs. Morphological studies shows the formation of nearly spherical nanoparticles. FTIR spectrum confirms the existence of various functional groups of biomolecules capping the nanoparticles. UV-visible spectrum displays single SPR band at 428 nm indicating the absence of anisotropic particles. The synthesized Ag NPs exhibited better antimicrobial property towards gram negative Escherichia coli and towards tested Penicillium spp. than other tested microorganisms using disc diffusion method. Finally it has proven that the synthesized bio-inspired Ag NPs have potent antimicrobial effect. Copyright © 2014 Elsevier B.V. All rights reserved.
Maqbool, Qaisar; Iftikhar, Sidra; Nazar, Mudassar; Abbas, Fazal; Saleem, Asif; Hussain, Talib; Kausar, Rizwan; Anwaar, Sadaf; Jabeen, Nyla
2017-06-01
In present investigation, copper oxide (CuO) nanostructures have been prepared via green chemistry. Olea europaea leaf extract act as strong chelating agent for tailoring physical as well as bio-medical characteristics of CuO at the nano-size. Physical characterisation such as scanning electron microscope analysis depicts the formation of homogenised spherical shape nanoparticles (NPs) with average size of 42 nm. X-ray diffraction and Fourier transform infrared spectroscopy further confirmed the crystalline pure phase and monoclinic structure. High performance liquid chromatography (HPLC) testing is performed to evaluate the relative concentration of bioactive molecules in the O. europaea leaf extract. From HPLC results capping action of organic molecules around CuO-NPs is hypothesised. The antimicrobial potency of biosynthesised CuO-NPs have been evaluated using colony forming unit (CFU) counting assay and disc diffusion method which shows a significant zone of inhibition against bacterial and fungal strains may be highly potential for future antimicrobial pharmaceutics. Furthermore, reduction of various precursors by plant extract will reduce environmental impact over chemical synthesis.
Fischer, R. A.
1968-01-01
This paper reports a consistent and large opening response to light + CO2-free air in living stomata of isolated epidermal strips of Vicia faba. The response was compared to that of non-isolated stomata in leaf discs floating on water; stomatal apertures, guard cell solute potentials and starch contents were similar in the 2 situations. To obtain such stomatal behavior, it was necessary to float epidermal strips on dilute KCl solutions. This suggests that solute uptake is necessary for stomatal opening. The demonstration of normal stomatal behavior in isolated epidermal strips provides a very useful system in which to investigate the mechanism of stomatal opening. It was possible to show independent responses in stomatal aperture to light and to CO2-free air. PMID:16656995
Kuiper belt analogues in nearby M-type planet-host systems
NASA Astrophysics Data System (ADS)
Kennedy, G. M.; Bryden, G.; Ardila, D.; Eiroa, C.; Lestrade, J.-F.; Marshall, J. P.; Matthews, B. C.; Moro-Martin, A.; Wyatt, M. C.
2018-06-01
We present the results of a Herschel survey of 21 late-type stars that host planets discovered by the radial velocity technique. The aims were to discover new discs in these systems and to search for any correlation between planet presence and disc properties. In addition to the known disc around GJ 581, we report the discovery of two new discs, in the GJ 433 and GJ 649 systems. Our sample therefore yields a disc detection rate of 14 per cent, higher than the detection rate of 1.2 per cent among our control sample of DEBRIS M-type stars with 98 per cent confidence. Further analysis however shows that the disc sensitivity in the control sample is about a factor of two lower in fractional luminosity than for our survey, lowering the significance of any correlation between planet presence and disc brightness below 98 per cent. In terms of their specific architectures, the disc around GJ 433 lies at a radius somewhere between 1 and 30 au. The disc around GJ 649 lies somewhere between 6 and 30 au, but is marginally resolved and appears more consistent with an edge-on inclination. In both cases the discs probably lie well beyond where the known planets reside (0.06-1.1 au), but the lack of radial velocity sensitivity at larger separations allows for unseen Saturn-mass planets to orbit out to ˜5 au, and more massive planets beyond 5 au. The layout of these M-type systems appears similar to Sun-like star + disc systems with low-mass planets.
Generating large misalignments in gapped and binary discs
NASA Astrophysics Data System (ADS)
Owen, James E.; Lai, Dong
2017-08-01
Many protostellar gapped and binary discs show misalignments between their inner and outer discs; in some cases, ˜70° misalignments have been observed. Here, we show that these misalignments can be generated through a secular resonance between the nodal precession of the inner disc and the precession of the gap-opening (stellar or massive planetary) companion. An evolving protostellar system may naturally cross this resonance during its lifetime due to disc dissipation and/or companion migration. If resonance crossing occurs on the right time-scale, of the order of a few million years, characteristic for young protostellar systems, the inner and outer discs can become highly misaligned, with misalignments ≳ 60° typical. When the primary star has a mass of order a solar mass, generating a significant misalignment typically requires the companion to have a mass of ˜0.01-0.1 M⊙ and an orbital separation of tens of astronomical units. The recently observed companion in the cavity of the gapped, highly misaligned system HD 142527 satisfies these requirements, indicating that a previous resonance crossing event misaligned the inner and outer discs. Our scenario for HD 142527's misaligned discs predicts that the companion's orbital plane is aligned with the outer disc's; this prediction should be testable with future observations as the companion's orbit is mapped out. Misalignments observed in several other gapped disc systems could be generated by the same secular resonance mechanism.
Preliminary optical coherence tomography investigation of the temporo-mandibular joint disc
NASA Astrophysics Data System (ADS)
Mărcăuteanu, Corina; Demjan, Enikö; Sinescu, Cosmin; Negrutiu, Meda; Motoc, Adrian; Lighezan, Rodica; Vasile, Liliana; Hughes, Mike; Bradu, Adrian; Dobre, George; Podoleanu, Adrian G.
2010-02-01
Aim and objectives. The morphology and position of the temporo-mandibular disc are key issues in the diagnosis and treatment of arthrogenous temporo-mandibular disorders. Magnetic resonance imaging and arthroscopy are used today to identify: flattening of the pars posterior of the disc, perforation and/or adhesions in the pars intermedia of the disc and disc displacements. The present study proposes the investigation of the temporo-mandibular joint disc by optical coherence tomography (OCT). Material and methods. 8 human temporo-mandibular joint discs were harvested from dead subjects, under 40 year of age, and conserved in formalin. They had a normal morphology, with a thicker pars posterior (2,6 mm on the average) and a thinner pars intermedia (1mm on the average). We investigated the disc samples using two different OCT systems: an en-face OCT (time domain (TD)-OCT) system, working at 1300 nm (C-scan and B-scan mode) and a spectral OCT system (a Fourier domain (FD)-OCT) system , working at 840 nm (B-scan mode). Results. The OCT investigation of the temporo-mandibular joint discs revealed a homogeneous microstructure. The longer wavelength of the TD-OCT offers a higher penetration depth (2,5 mm in air), which is important for the analysis of the pars posterior, while the FD-OCT is much faster. Conclusions: OCT is a promising imaging method for the microstructural characterization of the temporo-mandibular disc.
NASA Astrophysics Data System (ADS)
Imtithal I., J.; Mustapha, Wan Aida Wan; Idris A., B.
2018-04-01
The potential of using plant and plant-derived products as deterrent against pest of crops in the field and during postharvest period, is gaining increasing attention, due to rapid development of resistance to the synthetic insecticides and couple with the fact that natural insecticides constitute a rich source of bioactive compounds that are safe and biodegradable into non-toxic products. The aim of the present study was to evaluate the insecticidal effects of chloroform extract of Pandanus amaryllifolius L. leaves against diamondback moth, Plutella xylostella under laboratory conditions. The medicinal plants were collected around Kampong Sungai Siput, Lubok China, Malacca, Malaysia. The leaf disc immersion method was used to assess the insecticidal effects of Pandanus amaryllifolius L. leaves extract on the larvae as well as duration of the larval phase following feeding of the second instar larvae of diamondback on the treated leaf discs for 24 h at various concentrations (0.5, 1, 2, 4 and 8 mg/ml). Larval mortality was evaluated every 24 hours for a period of three days. Highest larval percent was observed at 72hrs post exposure with 86.67 % mortality at 8mg/ml concentration LC50 and LC90 value was calculated against different concentrations. It was recorded that lowest LC50 and LC90 values were observed after 72 h of exposure followed by 48 h at 2.84 mg/ml and 17.59 mg/ml respectively and 3.36 mg/ml and 28.59 mg/ml respectively at 48 h of exposure time. Both larvae mortality and duration of exposure were found to be directly related to the concentration of Pandan amaryllifolius L. leaves extract and inversely related to fecundity. The present study indicates that phytochemicals derived from Pandanus amaryllifolius L. leaf extracts are effective DBM control agent and the plant extracts may be useful for further IPM program.
The role of disc self-gravity in circumbinary planet systems - II. Planet evolution
NASA Astrophysics Data System (ADS)
Mutter, Matthew M.; Pierens, Arnaud; Nelson, Richard P.
2017-08-01
We present the results of hydrodynamic simulations examining migration and growth of planets embedded in self-gravitating circumbinary discs. The binary star parameters are chosen to mimic those of the Kepler-16, -34 and -35 systems; the aim of this study is to examine the role of disc mass in determining the stopping locations of migrating planets at the edge of the cavity created by the central binary. Disc self-gravity can cause significant shrinkage of the cavity for disc masses in excess of 5-10 × the minimum mass solar nebula model. Planets forming early in the disc lifetime can migrate through the disc and stall at locations closer to the central star than is normally the case for lower mass discs, resulting in closer agreement between simulated and observed orbital architecture. The presence of a planet orbiting in the cavity of a massive disc can prevent the cavity size from expanding to the size of a lower mass disc. As the disc mass reduces over long time-scales, this indicates that circumbinary planet systems retain memory of their initial conditions. Our simulations produce planetary orbits in good agreement with Keper-16b without the need for self-gravity; Kepler-34 analogue systems produce wide and highly eccentric cavities, and self-gravity improves the agreement between simulations and data. Kepler-35b is more difficult to explain in detail due to its relatively low mass, which results in the simulated stopping location being at a larger radius than that observed.
NASA Astrophysics Data System (ADS)
Peschken, N.; Athanassoula, E.; Rodionov, S. A.
2017-06-01
We study the effect of angular momentum on the surface density profiles of disc galaxies, using high-resolution simulations of major mergers whose remnants have downbending radial density profiles (type II). As described in the previous papers of this series, in this scenario, most of the disc mass is acquired after the collision via accretion from a hot gaseous halo. We find that the inner and outer disc scalelengths, as well as the break radius, correlate with the total angular momentum of the initial merging system, and are larger for high-angular momentum systems. We follow the angular momentum redistribution in our simulated galaxies, and find that like the mass, the disc angular momentum is acquired via accretion, I.e. to the detriment of the gaseous halo. Furthermore, high-angular momentum systems give more angular momentum to their discs, which directly affects their radial density profile. Adding simulations of isolated galaxies to our sample, we find that the correlations are valid also for disc galaxies evolved in isolation. We show that the outer part of the disc at the end of the simulation is populated mainly by inside-out stellar migration, and that in galaxies with higher angular momentum, stars travel radially further out. This, however, does not mean that outer disc stars (in type II discs) were mostly born in the inner disc. Indeed, generally the break radius increases over time, and not taking this into account leads to overestimating the number of stars born in the inner disc.
The role of disc self-gravity in circumbinary planet systems - I. Disc structure and evolution
NASA Astrophysics Data System (ADS)
Mutter, Matthew M.; Pierens, Arnaud; Nelson, Richard P.
2017-03-01
We present the results of two-dimensional hydrodynamic simulations of self-gravitating circumbinary discs around binaries whose parameters match those of the circumbinary planet-hosting systems Kepler-16, Kepler-34 and Kepler-35. Previous work has shown that non-self-gravitating discs in these systems form an eccentric precessing inner cavity due to tidal truncation by the binary, and planets which form at large radii migrate until stalling at this cavity. Whilst this scenario appears to provide a natural explanation for the observed orbital locations of the circumbinary planets, previous simulations have failed to match the observed planet orbital parameters. The aim of this work is to examine the role of self-gravity in modifying circumbinary disc structure as a function of disc mass, prior to considering the evolution of embedded circumbinary planets. In agreement with previous work, we find that for disc masses between one and five times the minimum mass solar nebula (MMSN), disc self-gravity affects modest changes in the structure and evolution of circumbinary discs. Increasing the disc mass to 10 or 20 MMSN leads to two dramatic changes in disc structure. First, the scale of the inner cavity shrinks substantially, bringing its outer edge closer to the binary. Secondly, in addition to the eccentric inner cavity, additional precessing eccentric ring-like features develop in the outer regions of the discs. If planet formation starts early in the disc lifetime, these changes will have a significant impact on the formation and evolution of planets and precursor material.
Campos, Diana; Alves, Artur; Lemos, Marco F L; Correia, António; Soares, Amadeu M V M; Pestana, João L T
2014-07-01
Detritus processing is vital for freshwater ecosystems that depend on the leaf litter from riparian vegetation and is mediated by microorganisms and aquatic invertebrates. Shredder invertebrates transform coarse particulate organic matter into fine particulate organic matter used as food by collector species. Direct and indirect effects of contaminants can impair detritus processing and thus affect the functioning of these ecosystems. Here, we assessed the combined effects of a toxic metal (cadmium) and resource quality (leaf species) on detritus processing and shredder-collector interactions. We considered two types of leaves, alder and eucalyptus that were microbially conditioned under different Cd concentrations in the laboratory. The microbial communities present on leaves were analyzed by Denaturing Gradient Gel Electrophoresis (DGGE), and we also measured microbial respiration rates. Sericostoma vittatum (a caddisfly shredder) and Chironomus riparius (a midge collector) were also exposed to Cd and allowed to consume the corresponding alder or eucalyptus leaves. We evaluated C. riparius growth and leaf mass loss in multispecies microcosms. Cadmium exposure affected leaf conditioning and fungal diversity on both leaf species, as assessed by DGGE. Cadmium exposure also affected the mass loss of alder leaves by reductions in detritivore feeding, and impaired C. riparius growth. Chironomus riparius consumed alder leaf discs in the absence of shredders, but S. vittatum appear to promote C. riparius growth in treatments containing eucalyptus. These results show that indirect effects of contaminants along detritus-processing chains can occur through effects on shredder-collector interactions such as facilitation but they also depend on the nutritional quality of detritus and on sensitivity and feeding plasticity of detritivore species.
Faizan, Ahmad; Goel, Vijay K; Biyani, Ashok; Garfin, Steven R; Bono, Christopher M
2012-03-01
Studies delineating the adjacent level effect of single level disc replacement systems have been reported in literature. The aim of this study was to compare the adjacent level biomechanics of bi-level disc replacement, bi-level fusion and a construct having adjoining level disc replacement and fusion system. In total, biomechanics of four models- intact, bi level disc replacement, bi level fusion and fusion plus disc replacement at adjoining levels- was studied to gain insight into the effects of various instrumentation systems on cranial and caudal adjacent levels using finite element analysis (73.6N+varying moment). The bi-level fusion models are more than twice as stiff as compared to the intact model during flexion-extension, lateral bending and axial rotation. Bi-level disc replacement model required moments lower than intact model (1.5Nm). Fusion plus disc replacement model required moment 10-25% more than intact model, except in extension. Adjacent level motions, facet loads and endplate stresses increased substantially in the bi-level fusion model. On the other hand, adjacent level motions, facet loads and endplate stresses were similar to intact for the bi-level disc replacement model. For the fusion plus disc replacement model, adjacent level motions, facet loads and endplate stresses were closer to intact model rather than the bi-level fusion model, except in extension. Based on our finite element analysis, fusion plus disc replacement procedure has less severe biomechanical effects on adjacent levels when compared to bi-level fusion procedure. Bi-level disc replacement procedure did not have any adverse mechanical effects on adjacent levels. Copyright © 2011 Elsevier Ltd. All rights reserved.
Action spectra for photosynthetic inhibition
NASA Technical Reports Server (NTRS)
Caldwell, M. M.; Flint, S.; Camp, L. B.
1981-01-01
The ultraviolet action spectrum for photosynthesis inhibition was determined to fall between that of the general DNA action spectrum and the generalized plant action spectrum. The characteristics of this action spectrum suggest that a combination of pronounced increase in effectiveness with decreasing wavelength, substantial specificity for the UV-B waveband, and very diminished response in the UV-A waveband result in large radiation amplification factors when the action spectra are used as weighting functions. Attempted determination of dose/response relationships for leaf disc inhibition provided inconclusive data from which to deconvolute an action spectrum.
An unbiased study of debris discs around A-type stars with Herschel
NASA Astrophysics Data System (ADS)
Thureau, N. D.; Greaves, J. S.; Matthews, B. C.; Kennedy, G.; Phillips, N.; Booth, M.; Duchêne, G.; Horner, J.; Rodriguez, D. R.; Sibthorpe, B.; Wyatt, M. C.
2014-12-01
The Herschel DEBRIS (Disc Emission via a Bias-free Reconnaissance in the Infrared/Submillimetre) survey brings us a unique perspective on the study of debris discs around main-sequence A-type stars. Bias-free by design, the survey offers a remarkable data set with which to investigate the cold disc properties. The statistical analysis of the 100 and 160 μm data for 86 main-sequence A stars yields a lower than previously found debris disc rate. Considering better than 3σ excess sources, we find a detection rate ≥24 ± 5 per cent at 100 μm which is similar to the debris disc rate around main-sequence F/G/K-spectral type stars. While the 100 and 160 μm excesses slowly decline with time, debris discs with large excesses are found around some of the oldest A stars in our sample, evidence that the debris phenomenon can survive throughout the length of the main sequence (˜1 Gyr). Debris discs are predominantly detected around the youngest and hottest stars in our sample. Stellar properties such as metallicity are found to have no effect on the debris disc incidence. Debris discs are found around A stars in single systems and multiple systems at similar rates. While tight and wide binaries (<1 and >100 au, respectively) host debris discs with a similar frequency and global properties, no intermediate separation debris systems were detected in our sample.
The diversity of planetary system architectures: contrasting theory with observations
NASA Astrophysics Data System (ADS)
Miguel, Y.; Guilera, O. M.; Brunini, A.
2011-10-01
In order to explain the observed diversity of planetary system architectures and relate this primordial diversity to the initial properties of the discs where they were born, we develop a semi-analytical model for computing planetary system formation. The model is based on the core instability model for the gas accretion of the embryos and the oligarchic growth regime for the accretion of the solid cores. Two regimes of planetary migration are also included. With this model, we consider different initial conditions based on recent results of protoplanetary disc observations to generate a variety of planetary systems. These systems are analysed statistically, exploring the importance of several factors that define the planetary system birth environment. We explore the relevance of the mass and size of the disc, metallicity, mass of the central star and time-scale of gaseous disc dissipation in defining the architecture of the planetary system. We also test different values of some key parameters of our model to find out which factors best reproduce the diverse sample of observed planetary systems. We assume different migration rates and initial disc profiles, in the context of a surface density profile motivated by similarity solutions. According to this, and based on recent protoplanetary disc observational data, we predict which systems are the most common in the solar neighbourhood. We intend to unveil whether our Solar system is a rarity or whether more planetary systems like our own are expected to be found in the near future. We also analyse which is the more favourable environment for the formation of habitable planets. Our results show that planetary systems with only terrestrial planets are the most common, being the only planetary systems formed when considering low-metallicity discs, which also represent the best environment for the development of rocky, potentially habitable planets. We also found that planetary systems like our own are not rare in the solar neighbourhood, its formation being favoured in massive discs where there is not a large accumulation of solids in the inner region of the disc. Regarding the planetary systems that harbour hot and warm Jupiter planets, we found that these systems are born in very massive, metal-rich discs. Also a fast migration rate is required in order to form these systems. According to our results, most of the hot and warm Jupiter systems are composed of only one giant planet, which is also shown by the current observational data.
Nonlinear dynamics of the human lumbar intervertebral disc.
Marini, Giacomo; Huber, Gerd; Püschel, Klaus; Ferguson, Stephen J
2015-02-05
Systems with a quasi-static response similar to the axial response of the intervertebral disc (i.e. progressive stiffening) often present complex dynamics, characterized by peculiar nonlinearities in the frequency response. However, such characteristics have not been reported for the dynamic response of the disc. The accurate understanding of disc dynamics is essential to investigate the unclear correlation between whole body vibration and low back pain. The present study investigated the dynamic response of the disc, including its potential nonlinear response, over a range of loading conditions. Human lumbar discs were tested by applying a static preload to the top and a sinusoidal displacement at the bottom of the disc. The frequency of the stimuli was set to increase linearly from a low frequency to a high frequency limit and back down. In general, the response showed nonlinear and asymmetric characteristics. For each test, the disc had different response in the frequency-increasing compared to the frequency-decreasing sweep. In particular, the system presented abrupt changes of the oscillation amplitude at specific frequencies, which differed between the two sweeps. This behaviour indicates that the system oscillation has a different equilibrium condition depending on the path followed by the stimuli. Preload and amplitude of the oscillation directly influenced the disc response by changing the nonlinear dynamics and frequency of the jump-phenomenon. These results show that the characterization of the dynamic response of physiological systems should be readdressed to determine potential nonlinearities. Their direct effect on the system function should be further investigated. Copyright © 2014 Elsevier Ltd. All rights reserved.
DOT National Transportation Integrated Search
1981-03-01
The Washington Metropolitan Area Transit Authority (WMATA) rail transit car design adopted the use of disc brakes as the primary friction braking system. Unfortunately, while disc brakes are more efficient than the traditional tread brake designs, th...
Adaptation to different host plant ages facilitates insect divergence without a host shift
Zhang, Bin; Segraves, Kari A.; Xue, Huai-Jun; Nie, Rui-E; Li, Wen-Zhu; Yang, Xing-Ke
2015-01-01
Host shifts and subsequent adaption to novel host plants are important drivers of speciation among phytophagous insects. However, there is considerably less evidence for host plant-mediated speciation in the absence of a host shift. Here, we investigated divergence of two sympatric sister elm leaf beetles, Pyrrhalta maculicollis and P. aenescens, which feed on different age classes of the elm Ulmus pumila L. (seedling versus adult trees). Using a field survey coupled with preference and performance trials, we show that these beetle species are highly divergent in both feeding and oviposition preference and specialize on either seedling or adult stages of their host plant. An experiment using artificial leaf discs painted with leaf surface wax extracts showed that host plant chemistry is a critical element that shapes preference. Specialization appears to be driven by adaptive divergence as there was also evidence of divergent selection; beetles had significantly higher survival and fecundity when reared on their natal host plant age class. Together, the results identify the first probable example of divergence induced by host plant age, thus extending how phytophagous insects might diversify in the absence of host shifts. PMID:26378220
NASA Astrophysics Data System (ADS)
Lubow, Stephen H.; Ogilvie, Gordon I.
2017-08-01
Recent results by Martin et al. showed in 3D smoothed particle hydrodynamics simulations that tilted discs in binary systems can be unstable to the development of global, damped Kozai-Lidov (KL) oscillations in which the discs exchange tilt for eccentricity. We investigate the linear stability of KL modes for tilted inviscid discs under the approximations that the disc eccentricity is small and the disc remains flat. By using 1D equations, we are able to probe regimes of large ratios of outer to inner disc edge radii that are realistic for binary systems of hundreds of astronomical unit separations and are not easily probed by multidimensional simulations. For order unity binary mass ratios, KL instability is possible for a window of disc aspect ratios H/r in the outer parts of a disc that roughly scale as (nb/n)2 ≲ H/r ≲ nb/n, for binary orbital frequency nb and orbital frequency n at the disc outer edge. We present a framework for understanding the zones of instability based on the determination of branches of marginally unstable modes. In general, multiple growing eccentric KL modes can be present in a disc. Coplanar apsidal-nodal precession resonances delineate instability branches. We determine the range of tilt angles for unstable modes as a function of disc aspect ratio. Unlike the KL instability for free particles that involves a critical (minimum) tilt angle, disc instability is possible for any non-zero tilt angle depending on the disc aspect ratio.
Liang, Hang; Deng, Xiangyu; Shao, Zengwu
2017-10-01
To summarize the research progress of intervertebral disc endogenous stem cells for intervertebral disc regeneration and deduce the therapeutic potential of endogenous repair for intervertebral disc degeneration. The original articles about intervertebral disc endogenous stem cells for intervertebral disc regeneration were extensively reviewed; the reparative potential in vivo and the extraction and identification in vitro of intervertebral disc endogenous stem cells were analyzed; the prospect of endogenous stem cells for intervertebral disc regeneration was predicted. Stem cell niche present in the intervertebral discs, from which stem cells migrate to injured tissues and contribute to tissues regeneration under certain specific microenvironment. Moreover, the migration of stem cells is regulated by chemokines system. Tissue specific progenitor cells have been identified and successfully extracted and isolated. The findings provide the basis for biological therapy of intervertebral disc endogenous stem cells. Intervertebral disc endogenous stem cells play a crucial role in intervertebral disc regeneration. Therapeutic strategy of intervertebral disc endogenous stem cells is proven to be a promising biological approach for intervertebral disc regeneration.
Impact of planet-planet scattering on the formation and survival of debris discs
NASA Astrophysics Data System (ADS)
Marzari, F.
2014-10-01
Planet-planet scattering is a major dynamical mechanism able to significantly alter the architecture of a planetary system. In addition to that, it may also affect the formation and retention of a debris disc by the system. A violent chaotic evolution of the planets can easily clear leftover planetesimal belts preventing the ignition of a substantial collisional cascade that can give origin to a debris disc. On the other end, a mild evolution with limited steps in eccentricity and semimajor axis can trigger the formation of a debris disc by stirring an initially quiet planetesimal belt. The variety of possible effects that planet-planet scattering can have on the formation of debris discs is analysed and the statistical probability of the different outcomes is evaluated. This leads to the prediction that systems which underwent an episode of chaotic evolution might have a lower probability of harbouring a debris disc.
NASA Astrophysics Data System (ADS)
Pierens, A.; Nelson, R. P.
2018-06-01
Although most of the circumbinary planets detected by the Kepler spacecraft are on orbits that are closely aligned with the binary orbital plane, the systems Kepler-413 and Kepler-453 exhibit small misalignments of ˜2.5°. One possibility is that these planets formed in a circumbinary disc whose midplane was inclined relative to the binary orbital plane. Such a configuration is expected to lead to a warped and twisted disc, and our aim is to examine the inclination evolution of planets embedded in these discs. We employed 3D hydrodynamical simulations that examine the disc response to the presence of a modestly inclined binary with parameters that match the Kepler-413 system, as a function of disc parameters and binary inclinations. The discs all develop slowly varying warps, and generally display very small amounts of twist. Very slow solid body precession occurs because a large outer disc radius is adopted. Simulations of planets embedded in these discs resulted in the planet aligning with the binary orbit plane for disc masses close to the minimum mass solar nebular, such that nodal precession of the planet was controlled by the binary. For higher disc masses, the planet maintains near coplanarity with the local disc midplane. Our results suggest that circumbinary planets born in tilted circumbinary discs should align with the binary orbit plane as the disc ages and loses mass, even if the circumbinary disc remains misaligned from the binary orbit. This result has important implications for understanding the origins of the known circumbinary planets.
Response of Carbon Dioxide Fixation to Water Stress
Plaut, Z.; Bravdo, B.
1973-01-01
Application of water stress to isolated spinach (Spinacia oleracea) chloroplasts by redutcion of the osmotic potentials of CO2 fixation media below −6 to −8 bars resulted in decreased rates of fixation regardless of solute composition. A decrease in CO2 fixation rate of isolated chloroplasts was also found when leaves were dehydrated in air prior to chloroplast isolation. An inverse response of CO2 fixation to osmotic potential of the fixation medium was found with chloroplasts isolated from dehydrated leaves—namely, fixation rate was inhibited at −8 bars, compared with −16 or −24 bars. Low leaf water potentials were found to inhibit CO2 fixation of intact leaf discs to almost the same degree as they did CO2 fixation by chloroplasts isolated from those leaves. CO2 fixation by intact leaves was decreased by 50 and 80% when water potentials were reduced from −7.1 to −9.6 and from −7.1 to −17.6 bars, respectively. Transpiration was decreased by only 40 and 60%, under the same conditions. However, correction for the increase in leaf temperature indicated transpiration decreases of 57 and 80%, similar to the relative decreases in CO2 fixation. Despite the 4-fold increase in leaf resistance to CO2 diffusion in the gas phase when the water potential of leaves was reduced from −6.5 to −14.0 bars, an additional increase of about 50% in mesophyll resistance was obtained. CO2 concentration at compensation also increased when leaf water potential was reduced. PMID:16658493
NASA Astrophysics Data System (ADS)
Suriano, Scott S.; Li, Zhi-Yun; Krasnopolsky, Ruben; Shang, Hsien
2018-06-01
Radial substructures in circumstellar discs are now routinely observed by Atacama Large Millimeter/submillimeter Array. There is also growing evidence that disc winds drive accretion in such discs. We show through 2D (axisymmetric) simulations that rings and gaps develop naturally in magnetically coupled disc-wind systems on the scale of tens of au, where ambipolar diffusion (AD) is the dominant non-ideal magnetohydrodynamic effect. In simulations where the magnetic field and matter are moderately coupled, the disc remains relatively laminar with the radial electric current steepened by AD into a thin layer near the mid-plane. The toroidal magnetic field sharply reverses polarity in this layer, generating a large magnetic torque that drives fast accretion, which drags the poloidal field into a highly pinched radial configuration. The reconnection of this pinched field creates magnetic loops where the net poloidal magnetic flux (and thus the accretion rate) is reduced, yielding dense rings. Neighbouring regions with stronger poloidal magnetic fields accrete faster, forming gaps. In better magnetically coupled simulations, the so-called avalanche accretion streams develop continuously near the disc surface, rendering the disc-wind system more chaotic. Nevertheless, prominent rings and gaps are still produced, at least in part, by reconnection, which again enables the segregation of the poloidal field and the disc material similar to the more diffusive discs. However, the reconnection is now driven by the non-linear growth of magnetorotational instability channel flows. The formation of rings and gaps in rapidly accreting yet laminar discs has interesting implications for dust settling and trapping, grain growth, and planet formation.
Design and implementation of optical system for Placido-disc topography
NASA Astrophysics Data System (ADS)
Sui, Chenghua; Wo, Shengjie; Cai, Pinggen; Gao, Nan; Xu, Danyang; Han, Yonghao; Du, Chunnian
2017-11-01
Corneal topography provides powerful support in the diagnosis and treatment of corneal disease by displaying the corneal surface topography in data or image format. To realize the precise detection of corneal surface topography, an optical system for the corneal topography that is based on a Placido disc is designed, which includes a ring distribution on a Placido disc, an imaging system and a collimating illumination system. First, a mathematical model that is based on the corneal topography working principles is established with MATLAB to determine the distribution of white-and-black rings on the Placido disc, in which the ellipsoid facial rings-target of the Placido disc is utilized. Second, the imaging lens structure is designed and optimized by Zemax software. Last, the collimating illumination lens structure is designed by paraxial ray trace equations. The quality of the corneal topography, which is based on our designed optical system, is evaluated. The high-contrast image of uniformly distributed white-and-black rings is observed through the CCD camera. Our optical system for the corneal topography has high precision, with a measuring region of the cornea with a diameter of approximately 10 mm. Therefore, the creation of this optical system offers guidance for designing and improving the optical system of Placido-disc topography.
Noris, E.; Vaira, A. M.; Caciagli, P.; Masenga, V.; Gronenborn, B.; Accotto, G. P.
1998-01-01
A functional capsid protein (CP) is essential for host plant infection and insect transmission in monopartite geminiviruses. We studied two defective genomic DNAs of tomato yellow leaf curl virus (TYLCV), Sic and SicRcv. Sic, cloned from a field-infected tomato, was not infectious, whereas SicRcv, which spontaneously originated from Sic, was infectious but not whitefly transmissible. A single amino acid change in the CP was found to be responsible for restoring infectivity. When the amino acid sequences of the CPs of Sic and SicRcv were compared with that of a closely related wild-type virus (TYLCV-Sar), differences were found in the following positions: 129 (P in Sic and SicRcv, Q in Sar), 134 (Q in Sic and Sar, H in SicRcv) and 152 (E in Sic and SicRcv, D in Sar). We constructed TYLCV-Sar variants containing the eight possible amino acid combinations in those three positions and tested them for infectivity and transmissibility. QQD, QQE, QHD, and QHE had a wild-type phenotype, whereas PHD and PHE were infectious but nontransmissible. PQD and PQE mutants were not infectious; however, they replicated and accumulated CP, but not virions, in Nicotiana benthamiana leaf discs. The Q129P replacement is a nonconservative change, which may drastically alter the secondary structure of the CP and affect its ability to form the capsid. The additional Q134H change, however, appeared to compensate for the structural modification. Sequence comparisons among whitefly-transmitted geminiviruses in terms of the CP region studied showed that combinations other than QQD are present in several cases, but never with a P129. PMID:9811744
NASA Astrophysics Data System (ADS)
Zanazzi, J. J.; Lai, Dong
2018-07-01
Many hot Jupiter (HJ) systems have been observed to have their stellar spin axis misaligned with the planet's orbital angular momentum axis. The origin of this spin-orbit misalignment and the formation mechanism of HJs remain poorly understood. A number of recent works have suggested that gravitational interactions between host stars, protoplanetary discs, and inclined binary companions may tilt the stellar spin axis with respect to the disc's angular angular momentum axis, producing planetary systems with misaligned orbits. These previous works considered idealized disc evolution models and neglected the gravitational influence of newly formed planets. In this paper, we explore how disc photoevaporation and planet formation and migration affect the inclination evolution of planet-star-disc-binary systems. We take into account planet-disc interactions and the gravitational spin-orbit coupling between the host star and the planet. We find that the rapid depletion of the inner disc via photoevaporation reduces the excitation of stellar obliquities. Depending on the formation and migration history of HJs, the spin-orbit coupling between the star and the planet may reduces and even completely suppress the excitation of stellar obliquities. Our work constrains the formation/migration history of HJs. On the other hand, planetary systems with `cold' Jupiters or close-in super-earths may experience excitation of stellar obliquities in the presence of distant inclined companions.
Leterrier, Marina; Atanassova, Rossitza; Laquitaine, Laurent; Gaillard, Cécile; Coutos-Thévenot, Pierre; Delrot, Serge
2003-04-01
Tobacco plants were transformed by leaf disc regeneration with the VvHT1 (Vitis vinifera hexose transporter 1) cDNA under the control of the constitutive CaMV 35S promoter in a sense or antisense orientation. Among the 20 sense plants and 10 antisense plants obtained, two sense plants showed a mutant phenotype when grown in vitro, with stunted growth and an increase in the (leaves+stem)/roots dry weight ratio. The rate of [(3)H]-glucose uptake in leaf discs from these plants was decreased to 25% of the value measured in control plants. The amount of VvHT1 transgene and of host monosaccharide transporter MST transcripts in the leaves were studied by RNA gel blot analysis. The VvHT1 transcripts were usually present, but the amount of MST transcripts was the lowest in the plants that exhibited the most marked phenotype. Although the phenotype was lost when the plants were transferred from in vitro to greenhouse conditions, it was found again in vitro in the progeny obtained by self-pollination or by back-cross. The data show that VvHT1 sense expression resulted in unidirectional post-transcriptional gene inactivation of MST in some of the transformants, with dramatic effects on growth. They provide the first example of plants modified for hexose transport by post-transcriptional gene silencing. Some of the antisense plants also showed reduced expression of MST, and decreased growth. These results indicate that, like the sucrose transporters, hexose transporters play an important role in assimilate transport and in morphogenesis.
Kuiper belt structure around nearby super-Earth host stars
NASA Astrophysics Data System (ADS)
Kennedy, Grant M.; Matrà, Luca; Marmier, Maxime; Greaves, Jane S.; Wyatt, Mark C.; Bryden, Geoffrey; Holland, Wayne; Lovis, Christophe; Matthews, Brenda C.; Pepe, Francesco; Sibthorpe, Bruce; Udry, Stéphane
2015-05-01
We present new observations of the Kuiper belt analogues around HD 38858 and HD 20794, hosts of super-Earth mass planets within 1 au. As two of the four nearby G-type stars (with HD 69830 and 61 Vir) that form the basis of a possible correlation between low-mass planets and debris disc brightness, these systems are of particular interest. The disc around HD 38858 is well resolved with Herschel and we constrain the disc geometry and radial structure. We also present a probable James Clerk Maxwell Telescope sub-mm continuum detection of the disc and a CO J = 2-1 upper limit. The disc around HD 20794 is much fainter and appears marginally resolved with Herschel, and is constrained to be less extended than the discs around 61 Vir and HD 38858. We also set limits on the radial location of hot dust recently detected around HD 20794 with near-IR interferometry. We present High Accuracy Radial velocity Planet Searcher upper limits on unseen planets in these four systems, ruling out additional super-Earths within a few au, and Saturn-mass planets within 10 au. We consider the disc structure in the three systems with Kuiper belt analogues (HD 69830 has only a warm dust detection), concluding that 61 Vir and HD 38858 have greater radial disc extent than HD 20794. We speculate that the greater width is related to the greater minimum planet masses (10-20 M⊕ versus 3-5 M⊕), arising from an eccentric planetesimal population analogous to the Solar system's scattered disc. We discuss alternative scenarios and possible means to distinguish among them.
DUst around NEarby Stars. The Survey Observational Results
NASA Technical Reports Server (NTRS)
Eiroa, C.; Marshall, J. P.; Mora, A.; Montesinos, B.; Absil, O.; Augereau, J. Ch.; Bayo, A.; Bryden, G.; Danchi, W.; delBurgo, C.;
2013-01-01
Context. Debris discs are a consequence of the planet formation process and constitute the fingerprints of planetesimal systems. Their solar system counterparts are the asteroid and Edgeworth-Kuiper belts.Aims. The DUNES survey aims at detecting extra-solar analogues to the Edgeworth-Kuiper belt around solar-type stars, putting in this way the solar system into context. The survey allows us to address some questions related to the prevalence and properties of planetesimal systems.Methods. We used Herschel PACS to observe a sample of nearby FGK stars. Data at 100 and 160 micron were obtained, complemented in some cases with observations at 70 micron, and at 250, 350 and 500 micron using SPIRE. The observing strategy was to integrate as deep as possible at 100 micron to detect the stellar photosphere. Results. Debris discs have been detected at a fractional luminosity level down to several times that of the Edgeworth-Kuiper belt. The incidence rate of discs around the DUNES stars is increased from a rate of approx. 12.1% +/- 5% before Herschel to approx 20.2 % +/- % 2. A significant fraction (approx. 52%) of the discs are resolved, which represents an enormous step ahead from the previously known resolved discs. Some stars are associated with faint far-IR excesses attributed to a new class of cold discs. Although it cannot be excluded that these excesses are produced by coincidental alignment of background galaxies, statistical arguments suggest that at least some of them are true debris discs. Some discs display peculiar SEDs with spectral indexes in the 70-160 micron range steeper than the Rayleigh-Jeans one. An analysis of the debris disc parameters suggests that a decrease might exist of the mean black body radius from the F-type to the K-type stars. In addition, a weak trend is suggested for a correlation of disc sizes and an anticorrelation of disc temperatures with the stellar age.
System modeling with the DISC framework: evidence from safety-critical domains.
Reiman, Teemu; Pietikäinen, Elina; Oedewald, Pia; Gotcheva, Nadezhda
2012-01-01
The objective of this paper is to illustrate the development and application of the Design for Integrated Safety Culture (DISC) framework for system modeling by evaluating organizational potential for safety in nuclear and healthcare domains. The DISC framework includes criteria for good safety culture and a description of functions that the organization needs to implement in order to orient the organization toward the criteria. Three case studies will be used to illustrate the utilization of the DISC framework in practice.
The dispersal of planet-forming discs: theory confronts observations.
Ercolano, Barbara; Pascucci, Ilaria
2017-04-01
Discs of gas and dust around million-year-old stars are a by-product of the star formation process and provide the raw material to form planets. Hence, their evolution and dispersal directly impact what type of planets can form and affect the final architecture of planetary systems. Here, we review empirical constraints on disc evolution and dispersal with special emphasis on transition discs, a subset of discs that appear to be caught in the act of clearing out planet-forming material. Along with observations, we summarize theoretical models that build our physical understanding of how discs evolve and disperse and discuss their significance in the context of the formation and evolution of planetary systems. By confronting theoretical predictions with observations, we also identify the most promising areas for future progress.
The dispersal of planet-forming discs: theory confronts observations
Pascucci, Ilaria
2017-01-01
Discs of gas and dust around million-year-old stars are a by-product of the star formation process and provide the raw material to form planets. Hence, their evolution and dispersal directly impact what type of planets can form and affect the final architecture of planetary systems. Here, we review empirical constraints on disc evolution and dispersal with special emphasis on transition discs, a subset of discs that appear to be caught in the act of clearing out planet-forming material. Along with observations, we summarize theoretical models that build our physical understanding of how discs evolve and disperse and discuss their significance in the context of the formation and evolution of planetary systems. By confronting theoretical predictions with observations, we also identify the most promising areas for future progress. PMID:28484640
N-body simulations of planet formation: understanding exoplanet system architectures
NASA Astrophysics Data System (ADS)
Coleman, Gavin; Nelson, Richard
2015-12-01
Observations have demonstrated the existence of a significant population of compact systems comprised of super-Earths and Neptune-mass planets, and a population of gas giants that appear to occur primarily in either short-period (<10 days) or longer period (>100 days) orbits. The broad diversity of system architectures raises the question of whether or not the same formation processes operating in standard disc models can explain these planets, or if different scenarios are required instead to explain the widely differing architectures. To explore this issue, we present the results from a comprehensive suite of N-body simulations of planetary system formation that include the following physical processes: gravitational interactions and collisions between planetary embryos and planetesimals; type I and II migration; gas accretion onto planetary cores; self-consistent viscous disc evolution and disc removal through photo-evaporation. Our results indicate that the formation and survival of compact systems of super-Earths and Neptune-mass planets occur commonly in disc models where a simple prescription for the disc viscosity is assumed, but such models never lead to the formation and survival of gas giant planets due to migration into the star. Inspired in part by the ALMA observations of HL Tau, and by MHD simulations that display the formation of long-lived zonal flows, we have explored the consequences of assuming that the disc viscosity varies in both time and space. We find that the radial structuring of the disc leads to conditions in which systems of giant planets are able to form and survive. Furthermore, these giants generally occupy those regions of the mass-period diagram that are densely populated by the observed gas giants, suggesting that the planet traps generated by radial structuring of protoplanetary discs may be a necessary ingredient for forming giant planets.
A highly dynamical debris disc in an evolved planetary system
NASA Astrophysics Data System (ADS)
Manser, Christopher
2017-08-01
Our HST/COS survey for the photospheric pollution by planetary debris undisputably demonstrates that at least 25% of white dwarfs host an evolved planetary system. The debris discs holding the material that accretes onto the white dwarf are produced by the tidal disruption of asteroids, and are observed in nearly 40 systems by infrared excess emission from micron-sized dust. In a small number of cases, we have also detected double-peaked Ca II 860 nm emission lines from a metal-rich gaseous disc in addition to photospheric pollution and circumstellar dust. Our ground-based monitoring of the brightest of these systems, SDSS J1228+1040, over the last eleven years shows a dramatic morphological change in the emission line profiles on the time-scale of years. The evolution of the line profiles is consistent with the precession of an eccentric disc on a period of 25 years, indicating a recent dynamical interaction within the underlying dust disc. This could either be related to the initial circularisation of the disc, or a secondary impact onto an existing disc. We expect that the accretion rate onto the white dwarf varies on the same timescale as the Ca II emission lines, and there is the tantalising possibility to detect changes in the bulk abundances, if the impact of a planetesimal with a different bulk abundance stirred up the disc. We request a small amount of COS time to monitor the debris abundances over the next three HST Cycles to test this hypothesis, and bolster our understanding of the late evolution of planetary systems.
What's NEW at the GES DISC: Evolution of Data Management and Services for Aura Mission and Beyond
NASA Technical Reports Server (NTRS)
Wei, Jennifer
2016-01-01
GES DISC world. Aura data usage and trend. Aura data users requests. GES DISC update (before/after); New Access method (ftp to http) with Earthdata Login System, New Website (DISC/Mirador to New Interface), New Giovanni (Giovanni to Now Federated). GES DISC support beyond Aura Mission; Multi-sensor coincident data subsets, Level 2 support (Sub-setter, Visualization), Data List.
Wei, Jing; Graziane, Nicholas M; Gu, Zhenglin; Yan, Zhen
2015-11-13
Association studies have suggested that Disrupted-in-Schizophrenia 1 (DISC1) confers a genetic risk at the level of endophenotypes that underlies many major mental disorders. Despite the progress in understanding the significance of DISC1 at neural development, the mechanisms underlying DISC1 regulation of synaptic functions remain elusive. Because alterations in the cortical GABA system have been strongly linked to the pathophysiology of schizophrenia, one potential target of DISC1 that is critically involved in the regulation of cognition and emotion is the GABAA receptor (GABAAR). We found that cellular knockdown of DISC1 significantly reduced GABAAR-mediated synaptic and whole-cell current, whereas overexpression of wild-type DISC1, but not the C-terminal-truncated DISC1 (a schizophrenia-related mutant), significantly increased GABAAR currents in pyramidal neurons of the prefrontal cortex. These effects were accompanied by DISC1-induced changes in surface GABAAR expression. Moreover, the regulation of GABAARs by DISC1 knockdown or overexpression depends on the microtubule motor protein kinesin 1 (KIF5). Our results suggest that DISC1 exerts an important effect on GABAergic inhibitory transmission by regulating KIF5/microtubule-based GABAAR trafficking in the cortex. The knowledge gained from this study would shed light on how DISC1 and the GABA system are linked mechanistically and how their interactions are critical for maintaining a normal mental state. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.
Is the spiral morphology of the Elias 2-27 circumstellar disc due to gravitational instability?
NASA Astrophysics Data System (ADS)
Hall, Cassandra; Rice, Ken; Dipierro, Giovanni; Forgan, Duncan; Harries, Tim; Alexander, Richard
2018-06-01
A recent Atacama Large Millimeter/submillimeter Array (ALMA) observation of the Elias 2-27 system revealed a two-armed structure extending out to ˜300 au in radius. The protostellar disc surrounding the central star is unusually massive, raising the possibility that the system is gravitationally unstable. Recent work has shown that the observed morphology of the system can be explained by disc self-gravity, so we examine the physical properties of the disc necessary to detect self-gravitating spiral waves. Using three-dimensional smoothed particle hydrodynamics, coupled with radiative transfer and synthetic ALMA imaging, we find that observable spiral structure can only be explained by self-gravity if the disc has a low opacity (and therefore efficient cooling), and is minimally supported by external irradiation. This corresponds to a very narrow region of parameter space, suggesting that, although it is possible for the spiral structure to be due to disc self-gravity, other explanations, such as an external perturbation, may be preferred.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Terry, P.L.
1989-01-01
Whether upgrading or developing a security system, investing in a solid state video recorder may prove to be quite prudent. Even though the initial cost of a solid state recorder may be more expensive, when comparing it to a disc recorder it is practically maintenance free. Thus, the cost effectiveness of a solid state video recorder over an extended period of time more than justifies the initial expense. This document illustrates the use of a solid state video recorder as a direct replacement. It replaces a mechanically driven disc recorder that existed in a synchronized video recording system. The originalmore » system was called the Universal Video Disc Recorder System. The modified system will now be referred to as the Solid State Video Recording System. 5 figs.« less
Forming Disc Galaxies In Major Mergers: Radial Density Profiles And Angular Momentum
NASA Astrophysics Data System (ADS)
Peschken, Nicolas; Athanassoula, E.; Rodionov, S. A.; Lambert, J. C.
2017-06-01
In Athanassoula et al. (2016), we used high resolution N-body hydrodynamical simulations to model the major merger between two disc galaxies with a hot gaseous halo each, and showed that the remnant is a spiral galaxy. The two discs are destroyed by the collision, but after the merger, accretion from the surrounding gaseous halo allows the building of a new disc in the remnant galaxy. In Peschken et al. (2017), we used these simulations to study the radial surface density profiles of the remnant galaxies with downbending profiles (type II), i.e. composed of an inner and an outer exponential disc separated by a break. We analyzed the effect of angular momentum on these profiles, and found that the inner and outer disc scalelengths, as well as the break radius, all increase linearly with the total angular momentum of the initial merging system. Following the angular momentum redistribution in our simulations, we find that the disc angular momentum is acquired via accretion from the gaseous halo. Furthermore, high angular momentum systems give more angular momentum to their discs, which affects directly their radial density profile.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Irvine, R.F.; Letcher, A.J.; Lander, D.J.
1989-03-01
Pea (Pisum sativum) leaf discs or swimming suspensions of Chlamydomonas eugametos were radiolabeled with ({sup 3}H)myo-inositol or ({sup 32}P)Pi and the lipids were extracted, deacylated, and their glycerol moieties removed. The resulting inositol trisphosphate and bisphosphate fractions were examined by periodate degradation, reduction and dephosphorylation, or by incubation with human red cell membranes. Their likely structures were identified as D-myo-inositol(1,4,5)trisphosphate and D-myo-inositol(1,4,)-bisphosphate. It is concluded that plants contain phosphatidylinositol(4)phosphate and phosphatidylinositol(4,5)bisphosphate; no other polyphosphoinositides were detected.
Zhang, Guo-Jin; Hu, Hai-Hua; Zhang, Cai-Fei; Tian, Xiao-Juan; Peng, Hui; Gao, Tian-Gang
2015-01-01
Aster tianmenshanensis G. J. Zhang & T. G. Gao, a new species of Asteraceae from southern China is described and illustrated based on evidence from morphology, micromorphology and molecular phylogeny. The new species is superficially similar to Aster salwinensis Onno in having rosettes of spatulate leaves and a solitary, terminal capitulum, but it differs by its glabrous leaf margins, unequal disc floret lobes and 1-seriate pappus. The molecular phylogenetic analysis, based on nuclear sequences ITS, ETS and chloroplast sequence trnL-F, showed that the new species was nested within the genus Aster and formed a well supported clade with Aster verticillatus (Reinw.) Brouillet et al. The new species differs from the latter in having unbranched stems, much larger capitula, unequal disc floret lobes, beakless achenes and persistent pappus. In particular, A. tianmenshanensis has very short stigmatic lines, only ca. 0.18 mm long and less than 1/3 of the length of sterile style tip appendages, remarkably different from its congeners. This type of stigmatic line, as far as we know, has not been found in any other species of Aster. The very short stigmatic lines plus the unequal disc floret lobes imply that the new species may have a very specialized pollination system, which may be a consequence of habitat specialization. The new species grows only on the limestone cliffs of Mt. Tianmen, Hunan Province, at the elevation of 1400 m. It could only be accessed when a plank walkway was built across the cliffs for tourists. As it is known only from an area estimated at less than 10 km2 and a walkway passes through this location, its habitat could be easily disturbed. This species should best be treated as Critically Endangered based on the International Union for Conservation of Nature Red List Categories and Criteria B2a.
Tian, Xiao-Juan; Peng, Hui; Gao, Tian-Gang
2015-01-01
Aster tianmenshanensis G. J. Zhang & T. G. Gao, a new species of Asteraceae from southern China is described and illustrated based on evidence from morphology, micromorphology and molecular phylogeny. The new species is superficially similar to Aster salwinensis Onno in having rosettes of spatulate leaves and a solitary, terminal capitulum, but it differs by its glabrous leaf margins, unequal disc floret lobes and 1-seriate pappus. The molecular phylogenetic analysis, based on nuclear sequences ITS, ETS and chloroplast sequence trnL-F, showed that the new species was nested within the genus Aster and formed a well supported clade with Aster verticillatus (Reinw.) Brouillet et al. The new species differs from the latter in having unbranched stems, much larger capitula, unequal disc floret lobes, beakless achenes and persistent pappus. In particular, A. tianmenshanensis has very short stigmatic lines, only ca. 0.18 mm long and less than 1/3 of the length of sterile style tip appendages, remarkably different from its congeners. This type of stigmatic line, as far as we know, has not been found in any other species of Aster. The very short stigmatic lines plus the unequal disc floret lobes imply that the new species may have a very specialized pollination system, which may be a consequence of habitat specialization. The new species grows only on the limestone cliffs of Mt. Tianmen, Hunan Province, at the elevation of 1400 m. It could only be accessed when a plank walkway was built across the cliffs for tourists. As it is known only from an area estimated at less than 10 km2 and a walkway passes through this location, its habitat could be easily disturbed. This species should best be treated as Critically Endangered based on the International Union for Conservation of Nature Red List Categories and Criteria B2a. PMID:26308863
Antimicrobial activity of Carpolobia lutea extracts and fractions.
Nwidu, Lucky L; Nwafor, Paul A; Vilegas, Wagner
2012-01-01
Carpolobia lutea (G. Don) (Polygalaceae) is a tropical medicinal plant putative in traditional medicines against gonorrhea, gingivitis, infertility, antiulcer and malaria. The present study evaluated the antimicrobial, antifungal and antihelicobacter effects of extracts C. lutea leaf, stem and root. The extracts were examined using the disc-diffusion and Microplates of 96 wells containing Muller-Hinton methods against some bacterial strains: Eschericia coli (ATCC 25922), E. coli (ATCC10418), Pseudomonas aeruginosa (ATCC 27853), Staphylococcus aureus (ATCC 25923), Staphyllococus aureus (ATCC 6571), Enterococcus faecalis (ATCC 29212) and Bacillus subtilis (NCTC 8853) and four clinical isolates: one fungi (Candida albican) and three bacteria (Salmonella, Sheigella and staphylococcus aureus). The Gram-positive bacteria: Staphylococcus aureus (ATCC 25923), Enterococcus faecalis (ATCC 29212), Bacillus subtilis (ATCC 19659) and the Gram-negative bacteria: Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Cândida albicans (ATCC 18804) and Helicobacter pylori (ATCC 43504). Some of these extracts were found to be active against some tested strains but activity against H. pylori was >1000mg/ml and good fungistatic activity against C. albican. The MIC against C. albican is in the order n-HF > CHF > ETF= EAF.The order of potency of fraction was the ethanol root > n-HF leaf > ethanol fraction stem > chloroform fraction leaf = ethyl acetate fraction leaf. Polyphenols were demonstrated in ethanol fraction, ethyl acetate fraction, crude ethyl acetate extract and ethanol extract, respectively. These polyphenols isolated may partly explain and support the use of C. lutea for the treatment of infectious diseases in traditional Ibibio medicine of Nigeria.
Design and analysis of Air flow duct for improving the thermal performance of disc brake rotor
NASA Astrophysics Data System (ADS)
Raja, T.; Mathiselvan, G.; Sreenivasulureddy, M.; Goldwin Xavier, X.
2017-05-01
safety in automotive engineering has been considered as a number one priority in development of new vehicle. A brake system is one of the most critical systems in the vehicle, without which the vehicle will put a passenger in an unsafe position. Temperature distribution on disc rotor brake and the performance brake of disc rotor is influenced by the air flow around the disc rotor. In this paper, the effect of air flow over the disc rotor is analyzed using the CFD software. The air flow over the disc rotor is increased by using a duct to supply more air flow over the disc rotor. The duct is designed to supply more air to the rotor surface and it can be placed in front of the vehicle for better performance. Increasing the air flow around the rotor will maximize the heat convection from the rotor surface. The rotor life and the performance can be improved.
Walraevens, Joris; Liu, Baoge; Meersschaert, Joke; Demaerel, Philippe; Delye, Hans; Depreitere, Bart; Vander Sloten, Jos; Goffin, Jan
2009-03-01
Degeneration of intervertebral discs and facet joints is one of the most frequently encountered spinal disorders. In order to describe and quantify degeneration and evaluate a possible relationship between degeneration and biomechanical parameters, e.g., the intervertebral range of motion and intradiscal pressure, a scoring system for degeneration is mandatory. However, few scoring systems for the assessment of degeneration of the cervical spine exist. Therefore, two separate objective scoring systems to qualitatively and quantitatively assess the degree of cervical intervertebral disc and facet joint degeneration were developed and validated. The scoring system for cervical disc degeneration consists of three variables which are individually scored on neutral lateral radiographs: "height loss" (0-4 points), "anterior osteophytes" (0-3 points) and "endplate sclerosis" (0-2 points). The scoring system for facet joint degeneration consists of four variables which are individually scored on neutral computed tomography scans: "hypertrophy" (0-2 points), "osteophytes" (0-1 point), "irregularity" on the articular surface (0-1 point) and "joint space narrowing" (0-1 point). Each variable contributes with varying importance to the overall degeneration score (max 9 points for the scoring system of cervical disc degeneration and max 5 points for facet joint degeneration). Degeneration of 20 discs and facet joints of 20 patients was blindly assessed by four raters: two neurosurgeons (one senior and one junior) and two radiologists (one senior and one junior), firstly based on first subjective impression and secondly using the scoring systems. Measurement errors and inter- and intra-rater agreement were determined. The measurement error of the scoring system for cervical disc degeneration was 11.1 versus 17.9% of the subjective impression results. This scoring system showed excellent intra-rater agreement (ICC = 0.86, 0.75-0.93) and excellent inter-rater agreement (ICC = 0.78, 0.64-0.88). Surgeons as well as radiologists and seniors as well as juniors obtained excellent inter- and intra-rater agreement. The measurement error of the scoring system for cervical facet joint degeneration was 20.1 versus 24.2% of the subjective impression results. This scoring system showed good intra-rater agreement (ICC = 0.71, 0.42-0.89) and fair inter-rater agreement (ICC = 0.49, 0.26-0.74). Both scoring systems fulfilled the criteria for recommendation proposed by Kettler and Wilke. Our scoring systems can be reliable and objective tools for assessing cervical disc and facet joint degeneration. Moreover, the scoring system of cervical disc degeneration was shown to be experience- and discipline-independent.
Srinivasan, C; Liu, Zongrang; Scorza, Ralph
2011-04-01
Transgenic plants of tobacco (Nicotiana tabacum L) and European plum (Prunus domestica L) were produced by transforming with the apple class 1 KNOX genes (MdKN1 and MdKN2) or corn KNOX1 gene. Transgenic tobacco plants were regenerated in vitro from transformed leaf discs cultured in a medium lacking cytokinin. Ectopic expression of KNOX genes retarded shoot growth by suppressing elongation of internodes in transgenic tobacco plants. Expression of each of the three KNOX1 genes induced malformation and extensive lobbing in tobacco leaves. In situ regeneration of adventitious shoots was observed from leaves and roots of transgenic tobacco plants expressing each of the three KNOX genes. In vitro culture of leaf explants and internode sections excised from in vitro grown MdKN1 expressing tobacco shoots regenerated adventitious shoots on MS (Murashige and Skoog 1962) basal medium in the absence of exogenous cytokinin. Transgenic plum plants that expressed the MdKN2 or corn KNOX1 gene grew normally but MdKN1 caused a significant reduction in plant height, leaf shape and size and produced malformed curly leaves. A high frequency of adventitious shoot regeneration (96%) was observed in cultures of leaf explants excised from corn KNOX1-expressing transgenic plum shoots. In contrast to KNOX1-expressing tobacco, leaf and internode explants of corn KNOX1-expressing plum required synthetic cytokinin (thidiazuron) in the culture medium to induce adventitious shoot regeneration. The induction of high-frequency regeneration of adventitious shoots in vitro from leaves and stem internodal sections of plum through the ectopic expression of a KNOX1 gene is the first such report for a woody perennial fruit trees.
Planetary migration in protoplanetary discs and outer Solar System architecture.
NASA Astrophysics Data System (ADS)
Crida, A.; Morbidelli, A.; Tsiganis, K.
2007-08-01
Planets form around stars in gaseous protoplanetary discs. Due to tidal effects, they perturb the gas distribution, which in turn affects their motion. If the planet is massive enough (see for instance Crida et al. 2006 for a criterion), it repels the gas efficiently and opens a gap around its orbit ; then, locked into its gap, the planet follows the disc viscous evolution, which generally consists in accretion onto the central star. This process is called type II migration and leads to the orbital decay of the planet on a timescale shorter than the disc lifetime. After a review of these processes, we will focus on the Solar System giant planets. Strong constraints suggest that they did not migrate significantly. Masset and Snellgrove (2001) have shown that the evolution of 2 giants planets in mean motion resonance in a common gap differs from the evolution of a single planet. For what concerns Jupiter and Saturn, we found that in some conditions on the disc parameter, they can avoid significant migration (Morbidelli and Crida 2007). Adding Uranus and Neptune to the system, six stable fully resonant configurations for the four giants in the gas disc appear. Of course, none of them correspond to the present configuration. However, after the gas disc phase, the system was surrounded by a planetesimal disk. Interactions with this debris disk make the planets slowly evolve, until an instability in reached. This destabilises the planetesimal disc and triggers the Late Heavy Bombardment, while the planets reach their actual position, like in the model by Tsiganis et al (2005) and Gomes et al (2005). Our simulations show a very satisfying case, opening the possibility for a dynamically consistent scenario of the outer Solar System evolution, starting from the gas phase.
López-Arredondo, Damar L; Herrera-Estrella, Luis
2013-05-01
Antibiotic and herbicide resistance genes are currently the most frequently used selectable marker genes for plant research and crop development. However, the use of antibiotics and herbicides must be carefully controlled because the degree of susceptibility to these compounds varies widely among plant species and because they can also affect plant regeneration. Therefore, new selectable marker systems that are effective for a broad range of plant species are still needed. Here, we report a simple and inexpensive system based on providing transgenic plant cells the capacity to convert a nonmetabolizable compound (phosphite, Phi) into an essential nutrient for cell growth (phosphate) trough the expression of a bacterial gene encoding a phosphite oxidoreductase (PTXD). This system is effective for the selection of Arabidopsis transgenic plants by germinating T0 seeds directly on media supplemented with Phi and to select transgenic tobacco shoots from cocultivated leaf disc explants using nutrient media supplemented with Phi as both a source of phosphorus and selective agent. Because the ptxD/Phi system also allows the establishment of large-scale screening systems under greenhouse conditions completely eliminating false transformation events, it should facilitate the development of novel plant transformation methods. © 2013 Society for Experimental Biology, Association of Applied Biologists and Blackwell Publishing Ltd.
The evolution of photoevaporating viscous discs in binaries
NASA Astrophysics Data System (ADS)
Rosotti, Giovanni P.; Clarke, Cathie J.
2018-02-01
A large fraction of stars are in binary systems, yet the evolution of protoplanetary discs in binaries has been little explored from the theoretical side. In this paper, we investigate the evolution of the discs surrounding the primary and secondary components of binary systems on the assumption that this is driven by photoevaporation induced by X-rays from the respective star. We show how for close enough separations (20-30 au for average X-ray luminosities) the tidal torque of the companion changes the qualitative behaviour of disc dispersal from inside out to outside in. Fewer transition discs created by photoevaporation are thus expected in binaries. We also demonstrate that in close binaries the reduction in viscous time leads to accelerated disc clearing around both components, consistent with unresolved observations. When looking at the differential disc evolution around the two components, in close binaries discs around the secondary clear first due to the shorter viscous time-scale associated with the smaller outer radius. In wide binaries instead the difference in photoevaporation rate makes the secondaries longer lived, though this is somewhat dependent on the assumed scaling of viscosity with stellar mass. We find that our models are broadly compatible with the growing sample of resolved observations of discs in binaries. We also predict that binaries have higher accretion rates than single stars for the same disc mass. Thus, binaries probably contribute to the observed scatter in the relationship between disc mass and accretion rate in young stars.
NAC Off-Vehicle Brake Testing Project
2007-05-01
disc pads/rotors and drum shoe assemblies/ drums - Must use vehicle “OEM” brake /hub-end hardware, or ESA... brake component comparison analysis (primary)* - brake system design analysis - brake system component failure analysis - (*) limited to disc pads...e.g. disc pads/rotors, drum shoe assemblies/ drums . - Not limited to “OEM” brake /hub-end hardware as there is none ! - Weight transfer, plumbing,
Simulating the X-ray luminosity of Be X-ray binaries: the case for black holes versus neutron stars
NASA Astrophysics Data System (ADS)
Brown, R. O.; Ho, W. C. G.; Coe, M. J.; Okazaki, A. T.
2018-04-01
There are over 100 Be stars that are known to have neutron star companions but only one such system with a black hole. Previous theoretical work suggests this is not due to their formation but due to differences in X-ray luminosity. It has also been proposed that the truncation of the Be star's circumstellar disc is dependent on the mass of the compact object. Hence, Be star discs in black hole binaries are smaller. Since accretion onto the compact object from the Be star's disc is what powers the X-ray luminosity, a smaller disc in black hole systems leads to a lower luminosity. In this paper, simulations are performed with a range of eccentricities and compact object mass. The disc's size and density are shown to be dependent on both quantities. Mass capture and, in turn, X-ray luminosity are heavily dependent on the size and density of the disc. Be/black hole binaries are expected to be up to ˜10 times fainter than Be/neutron star binaries when both systems have the same eccentricity and can be 100 times fainter when comparing systems with different eccentricity.
Petropoulos, Ioannis K; Pournaras, Jean-Antoine C; Stangos, Alexandros N; Pournaras, Constantin J
2009-01-01
To investigate the effect of systemic nitric oxide synthase (NOS) inhibition on optic disc oxygen partial pressure (PO(2)) in normoxia and hypercapnia. Intervascular optic disc PO(2) was measured in 12 anesthetized minipigs by using oxygen-sensitive microelectrodes placed <50 microm from the optic disc. PO(2) was measured continuously during 10 minutes under normoxia, hyperoxia (100% O(2)), carbogen breathing (95% O(2), 5% CO(2)), and hypercapnia (increased inhaled CO(2)). Measurements were repeated after intravenous injection of N(omega)-nitro-L-arginine methyl ester (L-NAME) 100 mg/kg. Intravenous L-arginine 100 mg/kg was subsequently given to three animals. Before L-NAME injection, an increase was observed in optic disc PO(2) during hypercapnia (DeltaPO(2) = 3.2 +/- 1.7 mm Hg; 18%; P = 0.001) and carbogen breathing (DeltaPO(2) = 12.8 +/- 5.1 mm Hg; 69%; P < 0.001). Optic disc PO(2) in normoxia remained stable for 30 minutes after L-NAME injection (4% decrease from baseline; P > 0.1), despite a 21% increase of mean arterial pressure. Optic disc PO(2) increase under hypercapnia was blunted after L-NAME injection (DeltaPO(2) = 0.6 +/- 1.1 mm Hg; 3%; P > 0.1), and this effect was reversible by L-arginine. Moreover, L-NAME reduced the response to carbogen by 29% (DeltaPO(2) = 9.1 +/- 4.4 mm Hg; 49%; P = 0.01 versus before L-NAME). The response to hyperoxia was not affected. Whereas systemic NOS inhibition did not affect optic disc PO(2) in normoxia, a blunting effect was noted on the CO(2)-induced optic disc PO(2) increase. Nitric oxide appears to mediate the hypercapnic optic disc PO(2) increase.
A wireless sequentially actuated microvalve system
NASA Astrophysics Data System (ADS)
Baek, Seung-Ki; Yoon, Yong-Kyu; Jeon, Hye-Seon; Seo, Soonmin; Park, Jung-Hwan
2013-04-01
A wireless microvalve system was fabricated based on induction heating for flow control in microfluidics by sequential valve opening. In this approach, we used paraffin wax as a flow plug, which can be changed from solid to liquid with adjacent heating elements operated by induction heating. Programmable opening of valves was devised by using different thermal responses of metal discs to a magnetic field. Copper and nickel discs with a diameter of 2.5 mm and various thicknesses (50, 100 and 200 µm) were prepared as heating elements by a laser cutting method, and they were integrated in the microfluidic channel as part of the microvalve. A calorimetric test was used to measure the thermal properties of the discs in terms of kinds of metal and disc thickness. Sequential openings of the microvalves were performed using the difference in the thermal response of 100 µm thick copper disc and 50 µm thick nickel disc for short-interval openings and 200 µm thick copper disc and 100-µm-thick nickel disc for long-interval openings. The thermal effect on fluid samples as a result of induction heating of the discs was studied by investigating lysozyme denaturation. More heat was generated in heating elements made of copper than in those made of nickel, implying differences in the thermal response of heating elements made of copper and nickel. Also, the thickness of the heating elements affected the thermal response in the elements. Valve openings for short intervals of 1-5 s and long intervals of 15-23 s were achieved by using two sets of heating elements. There was no significant change in lysozyme activity by increasing the temperature of the heating discs. This study demonstrates that a wireless sequentially actuated microvalve system can provide programmed valve opening, portability, ease of fabrication and operation, disposability, and low cost.
Joseph, Karunan; Ibrahim, Fatimah; Cho, Jongman; Thio, Tzer Hwai Gilbert; Al-Faqheri, Wisam; Madou, Marc
2015-01-01
The development of micro-power generators for centrifugal microfluidic discs enhances the platform as a green point-of-care diagnostic system and eliminates the need for attaching external peripherals to the disc. In this work, we present micro-power generators that harvest energy from the disc's rotational movement to power biomedical applications on the disc. To implement these ideas, we developed two types of micro-power generators using piezoelectric films and an electromagnetic induction system. The piezoelectric-based generator takes advantage of the film's vibration during the disc's rotational motion, whereas the electromagnetic induction-based generator operates on the principle of current generation in stacks of coil exposed to varying magnetic flux. We have successfully demonstrated that at the spinning speed of 800 revolutions per minute (RPM) the piezoelectric film-based generator is able to produce up to 24 microwatts using 6 sets of films and the magnetic induction-based generator is capable of producing up to 125 milliwatts using 6 stacks of coil. As a proof of concept, a custom made localized heating system was constructed to test the capability of the magnetic induction-based generator. The heating system was able to achieve a temperature of 58.62 °C at 2200 RPM. This development of lab-on-a-disc micro power generators preserves the portability standards and enhances the future biomedical applications of centrifugal microfluidic platforms.
NASA Astrophysics Data System (ADS)
Remigius, W. Dheelibun; Sarkar, Sunetra; Gupta, Sayan
2017-03-01
Use of heavy gases in centrifugal compressors for enhanced oil extraction have made the impellers susceptible to failures through acousto-elastic instabilities. This study focusses on understanding the dynamical behavior of such systems by considering the effects of the bounded fluid housed in a casing on a rotating disc. First, a mathematical model is developed that incorporates the interaction between the rotating impeller - modelled as a flexible disc - and the bounded compressible fluid medium in which it is immersed. The nonlinear effects arising due to large deformations of the disc have been included in the formulation so as to capture the post flutter behavior. A bifurcation analysis is carried out with the disc rotational speed as the bifurcation parameter to investigate the dynamical behavior of the coupled system and estimate the stability boundaries. Parametric studies reveal that the relative strengths of the various dissipation mechanisms in the coupled system play a significant role that affect the bifurcation route and the post flutter behavior in the acousto-elastic system.
System and method for continuous solids slurry depressurization
DOE Office of Scientific and Technical Information (OSTI.GOV)
Leininger, Thomas Frederick; Steele, Raymond Douglas; Yen, Hsien-Chin William
A continuous slag processing system includes a rotating parallel disc pump, coupled to a motor and a brake. The rotating parallel disc pump includes opposing discs coupled to a shaft, an outlet configured to continuously receive a fluid at a first pressure, and an inlet configured to continuously discharge the fluid at a second pressure less than the first pressure. The rotating parallel disc pump is configurable in a reverse-acting pump mode and a letdown turbine mode. The motor is configured to drive the opposing discs about the shaft and against a flow of the fluid to control a differencemore » between the first pressure and the second pressure in the reverse-acting pump mode. The brake is configured to resist rotation of the opposing discs about the shaft to control the difference between the first pressure and the second pressure in the letdown turbine mode.« less
Characterisation of glufosinate resistance mechanisms in Eleusine indica.
Jalaludin, Adam; Yu, Qin; Zoellner, Peter; Beffa, Roland; Powles, Stephen B
2017-06-01
An Eleusine indica population has evolved resistance to glufosinate, a major post-emergence herbicide of global agriculture. This population was analysed for target-site (glutamine synthetase) and non-target-site (glufosinate uptake, translocation and metabolism) resistance mechanisms. Glutamine synthetase (GS) activity extracted from susceptible (S) and resistant (R*) plants was equally sensitive to glufosinate inhibition, with IC 50 values of 0.85 mm and 0.99 mm, respectively. The extractable GS activity was also similar in S and R* samples. Foliar uptake of [ 14 C]-glufosinate did not differ in S and R* plants, nor did glufosinate net uptake in leaf discs. Translocation of [ 14 C]-glufosinate into untreated shoots and roots was also similar in both populations, with 44% to 47% of the herbicide translocated out from the treated leaf 24 h after treatment. The HPLC and LC-MS analysis of glufosinate metabolism revealed no major metabolites in S or R* leaf tissue. Glufosinate resistance in this resistant population is not due to an insensitive GS, or increased activity, or altered glufosinate uptake and translocation, or enhanced glufosinate metabolism. Thus, target-site resistance is likely excluded and the exact resistance mechanism(s) remain to be determined. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.
Montero, Javier; Gómez-Polo, Cristina
2016-06-01
The final color of a ceramic restoration is influenced by both the ceramic thickness and the cement shade. This study aims to evaluate the color stability according to the 3D Master System of e.max ceramic discs after bonding with different shades of luting agents. A total of 120 e.max.Press 2M1 HT ceramic discs (60 discs of 1-mm thick and 60 discs of 0.5 mm thick) and three different values of Variolink Veneer cement were used (-3, 0, +3) for the cementation process. An Easyshade compact device was used to measure color shade tabs, according to the 3D Master System, on the discs both before and after the cementation protocols. Bivariate and multivariate analyses were carried out with the spss v.21. After bonding with the different luting agents, only 30% remained as 2M1: specifically, 22% of the thinner discs and 37.3% of the thicker discs. In general, the effect of bonding increased the value and the chroma of the shade to a significant extent. Regression analyses revealed that the most significant predictor for all color parameters was cement shade, the thinner disc group bonded with -3 cement being the most unstable subgroup. According to the 3D Master System, the shade of the luting agent was the main predictor of the final color. However, the final color seems to be somewhat unpredictable, at least according to the modulating factors evaluated in the present study.
NASA Astrophysics Data System (ADS)
Manha, William D.
2010-09-01
Pressure relief devices are used in pressure systems and on pressure vessels to prevent catastrophic rupture or explosion from excessive pressure. Pressure systems and pressure vessels have manufacturers maximum rated operating pressures or maximum design pressures(MDP) for which there are relatively high safety factors and minimum risk of rupture or explosion. Pressure systems and pressure vessels that have a potential to exceed the MDP by being connected to another higher pressure source, a compressor, or heat to water(boiler) are required to have over-pressure protecting devices. Such devices can be relief valves and/or burst discs to safely relieve potentially excessive pressure and prevent unacceptable ruptures and explosions which result in fail-safe pressure systems and pressure vessels. Common aerospace relief valve and burst disc requirements and standards will be presented. This will include the NASA PSRP Interpretation Letter TA-88-074 Fault Tolerance of Systems Using Specially Certified Burst Disks that dictates burst disc requirements for payloads on Shuttle. Two recent undesirable manned space payloads pressure relief devices and practices will be discussed, as well as why these practices should not be continued. One example for discussion is the use of three burst discs that have been placed in series to comply with safety requirements of three controls to prevent a catastrophic hazard of the over-pressurization and rupture of pressure system and/or vessels. The cavities between the burst discs are evacuated and are the reference pressures for activating the two upstream burst discs. If the upstream burst disc leaks into the reference cavity, the reference pressure increases and it can increase the burst disc activating pressure and potentially result in the burst disc assembly being ineffective for over pressure protection. The three burst discs-in-series assembly was found acceptable because the burst discs are designed for minimum risk(DFMR) of leakage into the reference cavity. Since the burst discs are DFMR, a single burst disc would suffice, without adding the two leak-into-reference cavity failure modes. A single DFMR burst disc is preferable. An Alpha Magnetic Spectrometer - 02 burst disc assembly, with three-in-series burst discs test failure, necessitated the deletion of one of the burst discs, will be presented. Payload relief valves require periodic retests were extended significantly beyond the normal one year retest period because of the reduced ISS down mass capability which followed the Columbia accident. The acceptability of the extended retest period was determined by analysis, materials stability, benign environment, relatively inert fluid exposure, etc.(The policy letter, NC4-02-205 Guidelines for Certification and Verification of Pressure System Control Hardware, that permitted this action will be provided even though this application is not recommended for extending relief valve annual retest requirements.) The first crack pressure of a relief valve after an extended inactive period can be higher than the set crack pressure. Extrapolation of the extended inactive period and increased crack pressure could result in ineffective over pressure protection. Thus, relief valves with a ring or lever for activation are recommended so the relief valve can periodically be verified to open, functionality verified and the extended relief valve retest period should be discouraged. Stainless Steel cylindrical poppet-in-cylindrical housing check valves should never be used in a fluid with ions for an extended period of time, because the poppet is vulnerable to seizing or not functioning as a relief valve, even though the specifications, crack pressure, reseat pressure, maximum flow, and reseat leak look very much like the specifications for a relief valve. The technical reasons for this avoidance of using check valves as a relief valve will be discussed. The presentation will be summarized and recommendations made.
The Diverse Data, User Driven Services and the Power of Giovanni at NASA GES DISC
NASA Technical Reports Server (NTRS)
Shen, Suhung
2017-01-01
This presentation provides an overview of remote sensing and model data at GES (Goddard Earth Sciences) DISC (Data and Information Services Center); Overview of data services at GES DISC (Registration with NASA data system; Searching and downloading data); Giovanni (Geospatial Interactive Online VisualizationANd aNalysis Infrastructure): online data exploration tool; and NASA Earth Data and Information System.
Fernandez, Lorena E.; Koivunen, Marja; Yang, April; Flor-Weiler, Lina; Marrone, Pamela G.
2013-01-01
Isolate A396, a bacterium isolated from a Japanese soil sample demonstrated strong insecticidal and miticidal activities in laboratory bioassays. The isolate was characterized through biochemical methods, fatty acid methyl ester (FAME) analysis, sequencing of 16S rRNA, multilocus sequence typing and analysis, and DNA-DNA hybridization. FAME analysis matched A396 to Burkholderia cenocepacia, but this result was not confirmed by 16S rRNA or DNA-DNA hybridization. 16S rRNA sequencing indicated closest matches with B. glumae and B. plantarii. DNA-DNA hybridization experiments with B. plantarii, B. glumae, B. multivorans, and B. cenocepacia confirmed the low genetic similarity (11.5 to 37.4%) with known members of the genus. PCR-based screening showed that A396 lacks markers associated with members of the B. cepacia complex. Bioassay results indicated two mechanisms of action: through ingestion and contact. The isolate effectively controlled beet armyworms (Spodoptera exigua; BAW) and two-spotted spider mites (Tetranychus urticae; TSSM). In diet overlay bioassays with BAW, 1% to 4% (vol/vol) dilution of the whole-cell broth caused 97% to 100% mortality 4 days postexposure, and leaf disc treatment bioassays attained 75% ± 22% mortality 3 days postexposure. Contact bioassays led to 50% larval mortality, as well as discoloration, stunting, and failure to molt. TSSM mortality reached 93% in treated leaf discs. Activity was maintained in cell-free supernatants and after heat treatment (60°C for 2 h), indicating that a secondary metabolite or excreted thermostable enzyme might be responsible for the activity. Based on these results, we describe the novel species Burkholderia rinojensis, a good candidate for the development of a biocontrol product against insect and mite pests. PMID:24096416
Rajesh, Gururagavendra; Shenoy, Ramya; Rao, Ashwini
2016-01-01
Introduction Annona muricata also called as Soursop is a, flowering evergreen tree native to Mexico, Cuba, Central America and parts of India. The miracle tree as it is widely known as a natural cancer killer that is 10,000 times stronger than chemotherapy. Based on these miraculous claims, the leaves of these plants were used as an extract at varying concentrations as an antibacterial agent against oral pathogens. Aim The aim of the study was to assess antimicrobial efficacy of Soursop leaf extarct (Annona muricata) on Streptococcus mutans, Streptococcus mitis, Porphyromonas gingivalis, Prevotella intermedia and Candida albicans using disc diffusion method. Materials and Methods Extracts of Annona muricata leaves of concentrations of 1%, 5%, 10%, 15% and 20% were prepared. The anti-microbial efficacy was evaluated using disc diffusion method against Streptococcus mutans, Streptococcus mitis, Porphyromonas gingivalis, Prevotella intermedia and Candida albicans on agar plates. Results All concentrations of extracts were effective on the microbiota except for the P. Intermedia. The Soursop extract was highly effective on Candida species, with all concentrations exhibiting bactericidal and fungicidal property. The extracts at different concentration were effective when compared to the gold standard controls and the effect was statistically significant (p<0.05). Data obtained was analysed using one way analysis of variance (ANOVA) and Tukey’s post-hoc test. Conclusion The Soursop extracts were efficient for all test organisms expect P. intermedia. The present study demonstrated the in-vitro efficacy of Soursop was highest against S. mutans followed by C. albicans and least on P. intermedia. Hence, this study proves to an extent that the Soursop extract when used against oral microbiota has sufficient anti-microbial and fungicidal property. PMID:28050493
Giongo, A M M; Vendramim, J D; Freitas, S D L; Silva, M F G F
2016-12-01
The study was carried out to evaluate the bioactivity of secondary metabolites from Trichilia pallida, Trichilia pallens, and Toona ciliata against fall armyworm Spodoptera frugiperda (J. E. Smith) larvae. The studied compounds included (+/-)-catechins, a triglyceride, and cedrelone isolated from T. ciliata branches, fruits, and stems, respectively; dammaradienol isolated from T. pallida leaves; and scopoletin isolated from T. pallens branches. The compounds' activity was evaluated through ingestion and topic treatment. Treated artificial diet was offered to first instar larvae to evaluate ingestion effect, while an application on the dorsal thoracic region of third instar larvae was used to evaluate the topic effect. Mortality was assessed daily, and larval weight was recorded after 7 days for ingestion and 5 days for topic application. Scopoletin and triglyceride caused low mortality rates and reduction in larval weight by ingestion, (+/-)-catechins caused larval weight reduction by ingestion, and scopoletin reduced survival by topic treatment. The most effective compound was cedrelone that affected larval survival and development mainly by ingestion. The estimated LC 50 , LC 90 , and EC 50 for cedrelone were 0.0365, 0.0659, and 0.0095%, respectively. Further, cedrelone-treated corn leaf discs were offered to fourth instar larvae during 16 h in choice and no-choice tests. The deterrence indexes obtained in the choice tests were 23.5 and 36.3% at concentrations of 0.0365 and 0.0659, respectively. Consumption of cedrelone-treated leaf discs at the concentration of 0.0659% was lower compared to the control in the no-choice test. Thus, cedrelone caused lethal and sublethal effects and phagodeterrence on S. frugiperda and should be further studied.
Origin and evolution of two-component debris discs and an application to the q1 Eridani system
NASA Astrophysics Data System (ADS)
Schüppler, Christian; Krivov, Alexander V.; Löhne, Torsten; Booth, Mark; Kirchschlager, Florian; Wolf, Sebastian
2016-09-01
Many debris discs reveal a two-component structure, with an outer Kuiper-belt analogue and a warm inner component whose origin is still a matter of debate. One possibility is that warm emission stems from an `asteroid belt' closer in to the star. We consider a scenario in which a set of giant planets is formed in an initially extended planetesimal disc. These planets carve a broad gap around their orbits, splitting up the disc into the outer and the inner belts. After the gas dispersal, both belts undergo collisional evolution in a steady-state regime. This scenario is explored with detailed collisional simulations involving realistic physics to describe a long-term collisional depletion of the two-component disc. We find that the inner disc may be able to retain larger amounts of material at older ages than thought before on the basis of simplified analytic models. We show that the proposed scenario is consistent with a suite of thermal emission and scattered light observational data for a bright two-temperature debris disc around a nearby solar-type star q1 Eridani. This implies a Solar system-like architecture of the system, with an outer massive `Kuiper belt', an inner `asteroid belt', and a few Neptune- to Jupiter-mass planets in between.
NASA Astrophysics Data System (ADS)
Kraus, S.; Kluska, J.; Kreplin, A.; Bate, M.; Harries, T.; Hofmann, K.-H.; Hone, E.; Monnier, J.; Weigelt, G.; Anugu, N.; de Wit, W.-J..; Wittkowski, M.
2017-12-01
High-mass stars exhibit a significantly higher multiplicity frequency than low-mass stars, likely reflecting differences in how they formed. Theory suggests that high-mass binaries may form by the fragmentation of self-gravitational discs or by alternative scenarios such as disc-assisted capture. Near-infrared interferometric observations reveal the high-mass young stellar object IRAS 17216-3801 to be a close high-mass protobinary with a separation of 0.058 arcseconds ( 170 au). This is the closest high-mass protobinary system imaged to date. We also resolve near- infrared excess emission around the individual stars, which is associated with hot dust in circumstellar discs. These discs are strongly misaligned with respect to the binary separation vector, indicating that tidal forces have not yet had time to realign. We measure a higher accretion rate towards the circumsecondary disc, confirming a hydrodynamic effect where the secondary star disrupts the primary star’s accretion stream and effectively limits the mass that the primary star can accrete. NACO L'-band imaging may also have resolved the circumbinary disc that feeds the accretion onto the circumstellar discs. This discovery demonstrates the unique capabilities of the VLTI, creating exciting new opportunities to study the dynamical processes that govern the architecture of close multiple systems.
NASA Technical Reports Server (NTRS)
Petrucco, R. J.; Leonardi, S. J.
1973-01-01
The wetting characteristics and deposit forming tendencies of a series of lubricants were evaluated using a microfog jet delivery system to wet a flat heated rotating disc. The performances of the nine lubricants are discussed in terms of the various testing parameters which include temperature, disc speed and lubricant gas flow rates. Also discussed are the heat transfer characteristics of two of the lubricants on that same plane disc specimen. The wetting characteristics and heat transfer characteristics of one of the lubricants on a complex disc simulating bearing geometry are also discussed.
Gravitational instabilities in a protosolar-like disc - I. Dynamics and chemistry
NASA Astrophysics Data System (ADS)
Evans, M. G.; Ilee, J. D.; Boley, A. C.; Caselli, P.; Durisen, R. H.; Hartquist, T. W.; Rawlings, J. M. C.
2015-10-01
To date, most simulations of the chemistry in protoplanetary discs have used 1 + 1D or 2D axisymmetric α-disc models to determine chemical compositions within young systems. This assumption is inappropriate for non-axisymmetric, gravitationally unstable discs, which may be a significant stage in early protoplanetary disc evolution. Using 3D radiative hydrodynamics, we have modelled the physical and chemical evolution of a 0.17 M⊙ self-gravitating disc over a period of 2000 yr. The 0.8 M⊙ central protostar is likely to evolve into a solar-like star, and hence this Class 0 or early Class I young stellar object may be analogous to our early Solar system. Shocks driven by gravitational instabilities enhance the desorption rates, which dominate the changes in gas-phase fractional abundances for most species. We find that at the end of the simulation, a number of species distinctly trace the spiral structure of our relatively low-mass disc, particularly CN. We compare our simulation to that of a more massive disc, and conclude that mass differences between gravitationally unstable discs may not have a strong impact on the chemical composition. We find that over the duration of our simulation, successive shock heating has a permanent effect on the abundances of HNO, CN and NH3, which may have significant implications for both simulations and observations. We also find that HCO+ may be a useful tracer of disc mass. We conclude that gravitational instabilities induced in lower mass discs can significantly, and permanently, affect the chemical evolution, and that observations with high-resolution instruments such as Atacama Large Millimeter/submillimeter Array (ALMA) offer a promising means of characterizing gravitational instabilities in protosolar discs.
Debris disc constraints on planetesimal formation
NASA Astrophysics Data System (ADS)
Krivov, Alexander V.; Ide, Aljoscha; Löhne, Torsten; Johansen, Anders; Blum, Jürgen
2018-02-01
Two basic routes for planetesimal formation have been proposed over the last decades. One is a classical `slow-growth' scenario. Another one is particle concentration models, in which small pebbles are concentrated locally and then collapse gravitationally to form planetesimals. Both types of models make certain predictions for the size spectrum and internal structure of newly born planetesimals. We use these predictions as input to simulate collisional evolution of debris discs left after the gas dispersal. The debris disc emission as a function of a system's age computed in these simulations is compared with several Spitzer and Herschel debris disc surveys around A-type stars. We confirm that the observed brightness evolution for the majority of discs can be reproduced by classical models. Further, we find that it is equally consistent with the size distribution of planetesimals predicted by particle concentration models - provided the objects are loosely bound `pebble piles' as these models also predict. Regardless of the assumed planetesimal formation mechanism, explaining the brightest debris discs in the samples uncovers a `disc mass problem'. To reproduce such discs by collisional simulations, a total mass of planetesimals of up to ˜1000 Earth masses is required, which exceeds the total mass of solids available in the protoplanetary progenitors of debris discs. This may indicate that stirring was delayed in some of the bright discs, that giant impacts occurred recently in some of them, that some systems may be younger than previously thought or that non-collisional processes contribute significantly to the dust production.
On the energy dissipation rate at the inner edge of circumbinary discs
NASA Astrophysics Data System (ADS)
Terquem, Caroline; Papaloizou, John C. B.
2017-01-01
We study, by means of numerical simulations and analysis, the details of the accretion process from a disc on to a binary system. We show that energy is dissipated at the edge of a circumbinary disc and this is associated with the tidal torque that maintains the cavity: angular momentum is transferred from the binary to the disc through the action of compressional shocks and viscous friction. These shocks can be viewed as being produced by fluid elements that drift into the cavity and, before being accreted, are accelerated on to trajectories that send them back to impact the disc. The rate of energy dissipation is approximately equal to the product of potential energy per unit mass at the disc's inner edge and the accretion rate, estimated from the disc parameters just beyond the cavity edge, that would occur without the binary. For very thin discs, the actual accretion rate on to the binary may be significantly less. We calculate the energy emitted by a circumbinary disc taking into account energy dissipation at the inner edge and also irradiation arising there from reprocessing of light from the stars. We find that, for tight PMS binaries, the SED is dominated by emission from the inner edge at wavelengths between 1-4 and 10 μm. This may apply to systems like CoRoT 223992193 and V1481 Ori.
Inestabilidad radiativa en un disco de acreción en sistemas binarios interactuantes
NASA Astrophysics Data System (ADS)
De Vito, M. A.; Benvenuto, O. G.; Horvath, J. E.
2016-08-01
Close binary systems are formed by a varied family of objects, in particular, the named redback systems, i.e. the donor star transfers material to the neutron star, putting it in an accretion disc surrounding this star. Later, this material falls on the neutron star. In the last years it was observed that some members of the redback family experienced transition from the state of low mass X-ray binary system to the pulsar state, and in the opposite way. The time scales associated with these transitions suggest that they are related to instabilities in the accretion disc. That fact motivates us to model the accretion disc around the neutron star in this kind of systems. We present our first results, associated with instabilities in the disc by irradiation of the neutron star.
Synthesis of Organic Matter of Prebiotic Chemistry at the Protoplanetary Disc
NASA Astrophysics Data System (ADS)
Snytnikov, Valeriy; Stoynovskaya, Olga; Rudina, Nina
We have carried out scanning electron microscopic examination of CM carbonaceous chondrites meteorites Migey, Murchison, Staroe Boriskino aged more than 4.56 billion years (about 50 million years from the beginning of the formation of the Solar system). Our study confirmed the conclusion of Rozanov, Hoover and other researchers about the presence of microfossils of bacterial origin in the matrix of all these meteorites. Since the time of the Solar system formation is 60 - 100 million years, the primary biocenosis emerged in the protoplanetary disc of the Solar system before meteorites or simultaneously with them. It means that prebiological processes and RNA world appeared even earlier in the circumsolar protoplanetary disc. Most likely, this appearance of prebiotic chemistry takes place nowday in massive and medium-massive discs of the observed young stellar objects (YSO) class 0 and I. The timescale of the transition from chemical to biological evolution took less than 50 million years for the Solar system. Further evolution of individual biocenosis in a protoplanetary disc associated with varying physico-chemical conditions during the formation of the Solar system bodies. Biocenosis on these bodies could remove or develop under the influence of many cosmic factors and geological processes in the case of Earth. To complete the primary biosphere formation in short evolution time - millions of years - requires highly efficient chemical syntheses. In industrial chemistry for the efficient synthesis of ammonia, hydrogen cyanide, methanol and other organic species, that are the precursors to obtain prebiotic compounds, catalytic reactors of high pressure are used. Thus (1) necessary amount of the proper catalyst in (2) high pressure areas of the disc can trigger these intense syntheses. The disc contains the solids with the size from nanoparticle to pebble. Iron and magnesium is catalytically active ingredient for such solids. The puzzle is a way to provide hydrogen pressure inside the disc from tens to hundred atmospheres. We simulated unsteady processes in massive circumstellar discs around YSO class O and I. In the computational experiments, we have shown that at a certain stage of its evolution the circumstellar discs of gas and solids produces local areas of high pressure. According to the classical heterogeneous catalysis, a wide range of organic and prebiotic compounds could have been synthesized in these areas. Can we capture these areas of high pressure synthesis in observation of circumstellar discs? Due to the small sizes of such areas they can be hardly ever resolved even with the modern telescopes such as ALMA. However, we can try to detect their signatures in the disc, since the gas of the disc keep the set of organic synthesis products. The idea is to define the signature of the process using laboratory experiments. Varying gas temperature and pressure in laboratory setup we can carry out the catalytic high pressure syntheses and specify the set of gaseous products. These sets of organic compounds observed in the discs may serve as indicators of the emergence of high-pressure areas of prebiotic chemistry. Thus, there is a special interest to the study of YSO class 0 and I by means of observational astronomy. For these objects, first data on the presence of individual organic compounds in massive hydrogen-helium component of the discs appear. The origin of the organic compounds that are associated with chemical reactions in the discs should be separated from the set of organic compounds of the initial molecular cloud.
DEMONSTRATION OF BULLETIN: DISC TUBE™ MODULE TECHNOLOGY ROCHEM SEPARATION SYSTEMS, INC.
The Rochem Disc Tube™ Module System uses membrane separation to treat aqueous solutions ranging from seawater to leachate contaminated with organic solvents. The system uses reverse osmosis through a semipermeable membrane to separate purified water from contaminated liquids. Osm...
Planet signatures and Size Segregation in Debris Discs
NASA Astrophysics Data System (ADS)
Thébault, Philippe
2014-01-01
The response of a debris disc to a planetary perturber is the result of the complex interplay between gravitational effects, grain collisions and stellar radiation pressure (Stark & Kuchner (2009). We investigate to what extent this response can depart from the pure gravitational case when including grain collisional production and radiation pressure. We use the DyCoSS code (Thébault (2012), designed to study the coupled effect of collisions and dynamics for systems at steady state with one perturbing body. We focus on two outcomes: the 2D surface density profile of the disc+planet system, and the way the Particle Size Distribution (PSD) is spatially segregated within the disc. We consider two set-ups: 1) a narrow ring with an exterior ``shepherding'' planet, and 2) an extended disc in which a planet is embedded. For each case, the planet mass and orbit are explored as free parameters, and an unperturbed ``no-planet'' case is also considered. Another parameter is the disc's collisional activity, as parameterized by its optical depth τ.
A photoevaporative gap in the closest planet-forming disc
NASA Astrophysics Data System (ADS)
Ercolano, Barbara; Rosotti, Giovanni P.; Picogna, Giovanni; Testi, Leonardo
2017-01-01
The dispersal of the circum-stellar discs of dust and gas surrounding young low-mass stars has important implications for the formation of planetary systems. Photoevaporation from energetic radiation from the central object is thought to drive the dispersal in the majority of discs, by creating a gap which disconnects the outer from the inner regions of the disc and then disperses the outer disc from the inside-out, while the inner disc keeps draining viscously on to the star. In this Letter, we show that the disc around TW Hya, the closest protoplanetary disc to Earth, may be the first object where a photoevaporative gap has been imaged around the time at which it is being created. Indeed, the detected gap in the Atacama large millimeter/submillimeter array images is consistent with the expectations of X-ray photoevaporation models, thus not requiring the presence of a planet. The photoevaporation model is also consistent with a broad range of properties of the TW Hya system, e.g. accretion rate and the location of the gap at the onset of dispersal. We show that the central, unresolved 870 μm continuum source might be produced by free-free emission from the gas and/or residual dust inside the gap.
Evolution of an accretion disc in binary black hole systems
NASA Astrophysics Data System (ADS)
Kimura, Shigeo S.; Takahashi, Sanemichi Z.; Toma, Kenji
2017-03-01
We investigate evolution of an accretion disc in binary black hole (BBH) systems and possible electromagnetic counterparts of the gravitational waves from mergers of BBHs. Perna et al. proposed a novel evolutionary scenario of an accretion disc in BBHs in which a disc eventually becomes 'dead', I.e. the magnetorotational instability (MRI) becomes inactive. In their scenario, the dead disc survives until a few seconds before the merger event. We improve the dead disc model and propose another scenario, taking account of effects of the tidal torque from the companion and the critical ionization degree for MRI activation more carefully. We find that the mass of the dead disc is much lower than that in the Perna's scenario. When the binary separation sufficiently becomes small, the mass inflow induced by the tidal torque reactivates MRI, restarting mass accretion on to the black hole. We also find that this disc 'revival' happens more than thousands of years before the merger. The mass accretion induced by the tidal torque increases as the separation decreases, and a relativistic jet could be launched before the merger. The emissions from these jets are too faint compared to gamma-ray bursts, but detectable if the merger events happen within ≲10 Mpc or if the masses of the black holes are as massive as ˜105 M⊙.
Design and simulation of a new bidirectional actuator for haptic systems featuring MR fluid
NASA Astrophysics Data System (ADS)
Hung, Nguyen Quoc; Tri, Diep Bao; Cuong, Vo Van; Choi, Seung-Bok
2017-04-01
In this research, a new configuration of bidirectional actuator featuring MR fluid (BMRA) is proposed for haptic application. The proposed BMRA consists of a driving disc, a driving housing and a driven disc. The driving disc is placed inside the driving housing and rotates counter to each other by a servo DC motor and a bevel gear system. The driven shaft is also placed inside the housing and next to the driving disc. The gap between the two disc and the gap between the discs and the housing are filled with MR fluid. On the driven disc, two mutual magnetic coils are placed. By applying currents to the two coils mutually, the torque at the output shaft, which is fixed to the driven disc, can be controlled with positive, zero or negative value. This make the actuator be suitable for haptic application. After a review of MR fluid and its application, configuration of the proposed BMRA is presented. The modeling of the actuator is then derived based on Bingham rheological model of MRF and magnetic finite element analysis (FEA). The optimal design of the actuator is then performed to minimize the mass of the BMRA. From the optimal design result, performance characteristics of the actuator is simulated and detailed design of a prototype actuator is conducted.
Rationale, principles and experimental evaluation of the concept of soft stabilization.
Mulholland, Robert C; Sengupta, Dilip K
2002-10-01
The apparent clinical success of spinal stabilization methods that restrict rather than abolish movement in relieving mechanical back pain indicates that the concept of the aetiology of back pain should be reviewed. Further understanding of how degeneration affects disc biomechanics, and an understanding of how current soft stabilization systems alters them, may allow us to define more precisely what are the essential requirements of an ideal soft stabilization system. It appears that abnormal patterns of loading rather than abnormal movement are the reason that disc degeneration causes back pain in some patients. Abnormal load transmission is the principal cause of pain in osteoarthritic joints, and both osteotomy and, indeed, joint replacement succeed because they alter the load transmission across the joint. This concept is supported by the fact that abnormal patterns of stress distribution measured across the disc correlate with painful discs on discography. Clinically, it is often noted that back pain is primarily related to position or posture, rather than movement of the lumbar spine. Clinical success after solid fusion is unpredictable because it does not necessarily prevent painful loading across the disc, and also it may interfere with maintenance of sagittal balance in varying postures. The Graf ligament restricted flexion, and was modestly successful. It unfortunately increased the load over the posterior annulus. The Dynesys system reduces movement both in flexion and extension, and appears to be more successful. However, often it also unloads the disc to a degree that is unpredictable. The authors believe that this unloading of the disc is an important feature of a flexible stabilization system. A new a design of a flexible stabilization system has recently been described in an in vitro study, which unloads the disc by introduction of a load-sharing fulcrum near the axis of movement together with an elastic posterior ligament. This design produces maximal unloading of the disc, whilst allowing a restricted range of movement, which serves the important purpose of allowing the patient to maintain sagittal balance in varying postures.
Disrupted in schizophrenia 1 and synaptic function in the mammalian central nervous system
Randall, Andrew D; Kurihara, Mai; Brandon, Nicholas J; Brown, Jon T
2014-01-01
The disrupted in schizophrenia 1 (DISC1) gene is found at the breakpoint of an inherited chromosomal translocation, and segregates with major mental illnesses. Its potential role in central nervous system (CNS) malfunction has triggered intensive investigation of the biological roles played by DISC1, with the hope that this may shed new light on the pathobiology of psychiatric disease. Such work has ranged from investigations of animal behavior to detailed molecular-level analysis of the assemblies that DISC1 forms with other proteins. Here, we discuss the evidence for a role of DISC1 in synaptic function in the mammalian CNS. PMID:24712987
Debris Discs: Modeling/theory review
NASA Astrophysics Data System (ADS)
Thébault, P.
2012-03-01
An impressive amount of photometric, spectroscopic and imaging observations of circumstellar debris discs has been accumulated over the past 3 decades, revealing that they come in all shapes and flavours, from young post-planet-formation systems like Beta-Pic to much older ones like Vega. What we see in these systems are small grains, which are probably only the tip of the iceberg of a vast population of larger (undetectable) collisionally-eroding bodies, leftover from the planet-formation process. Understanding the spatial structure, physical properties, origin and evolution of this dust is of crucial importance, as it is our only window into what is going on in these systems. Dust can be used as a tracer of the distribution of their collisional progenitors and of possible hidden massive pertubers, but can also allow to derive valuable information about the disc's total mass, size distribution or chemical composition. I will review the state of the art in numerical models of debris disc, and present some important issues that are explored by current modelling efforts: planet-disc interactions, link between cold (i.e. Herschel-observed) and hot discs, effect of binarity, transient versus continuous processes, etc. I will finally present some possible perspectives for the development of future models.
Choosing an Optical Disc System: A Guide for Users and Resellers.
ERIC Educational Resources Information Center
Vane-Tempest, Stewart
1995-01-01
Presents a guide for selecting an optional disc system. Highlights include storage hierarchy; standards; data life cycles; security; implementing an optical jukebox system; optimizing the system; performance; quality and reliability; software; cost of online versus near-line; and growing opportunities. Sidebars provide additional information on…
CFD Modeling and Simulation of Aeorodynamic Cooling of Automotive Brake Rotor
NASA Astrophysics Data System (ADS)
Belhocien, Ali; Omar, Wan Zaidi Wan
Braking system is one of the important control systems of an automotive. For many years, the disc brakes have been used in automobiles for the safe retarding of the vehicles. During the braking enormous amount of heat will be generated and for effective braking sufficient heat dissipation is essential. The thermal performance of disc brake depends upon the characteristics of the airflow around the brake rotor and hence the aerodynamics is an important in the region of brake components. A CFD analysis is carried out on the braking system as a case study to make out the behavior of airflow distribution around the disc brake components using ANSYS CFX software. We are interested in the determination of the heat transfer coefficient (HTC) on each surface of a ventilated disc rotor varying with time in a transient state using CFD analysis, and then imported the surface film condition data into a corresponding FEM model for disc temperature analysis.
Potential of tissue culture for breeding root-knot nematode resistance into vegetables.
Fassuliotis, G; Bhatt, D P
1982-01-01
Plant protoplast technology is being investigated as a means of transferring root-knot nematode resistance factors from Solanum sisymbriifolium into the susceptible S. melongena. Solanum sisymbriifolium plants regenerated from callus lost resistance to Meloidogyne javanica but retained resistance to M. incognita. Tomato plants cloned from leaf discs of the root-knot nematode resistant 'Patriot' were completely susceptible to M. incognita, while sections of stems and leaves rooted in sand in the absence of growth hormones retained resistance. Changes in resistance persisted for three generations. It is postulated that the exogenous hormonal constituents of the culture medium are modifying the expression of genetic resistance.
Exogenous nitric oxide improves sugarcane growth and photosynthesis under water deficit.
Silveira, Neidiquele M; Frungillo, Lucas; Marcos, Fernanda C C; Pelegrino, Milena T; Miranda, Marcela T; Seabra, Amedea B; Salgado, Ione; Machado, Eduardo C; Ribeiro, Rafael V
2016-07-01
Nitric oxide (NO)-mediated redox signaling plays a role in alleviating the negative impact of water stress in sugarcane plants by improving root growth and photosynthesis. Drought is an environmental limitation affecting sugarcane growth and yield. The redox-active molecule nitric oxide (NO) is known to modulate plant responses to stressful conditions. NO may react with glutathione (GSH) to form S-nitrosoglutathione (GSNO), which is considered the main reservoir of NO in cells. Here, we investigate the role of NO in alleviating the effects of water deficit on growth and photosynthesis of sugarcane plants. Well-hydrated plants were compared to plants under drought and sprayed with mock (water) or GSNO at concentrations ranging from 10 to 1000 μM. Leaf GSNO sprayed plants showed significant improvement of relative water content and leaf and root dry matter under drought compared to mock-sprayed plants. Additionally, plants sprayed with GSNO (≥ 100 μM) showed higher leaf gas exchange and photochemical activity as compared to mock-sprayed plants under water deficit and after rehydration. Surprisingly, a raise in the total S-nitrosothiols content was observed in leaves sprayed with GSH or GSNO, suggesting a long-term role of NO-mediated responses to water deficit. Experiments with leaf discs fumigated with NO gas also suggested a role of NO in drought tolerance of sugarcane plants. Overall, our data indicate that the NO-mediated redox signaling plays a role in alleviating the negative effects of water stress in sugarcane plants by protecting the photosynthetic apparatus and improving shoot and root growth.
NASA GES DISC Level 2 Aerosol Analysis and Visualization Services
NASA Technical Reports Server (NTRS)
Wei, Jennifer; Petrenko, Maksym; Ichoku, Charles; Yang, Wenli; Johnson, James; Zhao, Peisheng; Kempler, Steve
2015-01-01
Overview of NASA GES DISC Level 2 aerosol analysis and visualization services: DQViz (Data Quality Visualization)MAPSS (Multi-sensor Aerosol Products Sampling System), and MAPSS_Explorer (Multi-sensor Aerosol Products Sampling System Explorer).
The Formation and Fragmentation of Primordial Protostellar Discs
NASA Astrophysics Data System (ADS)
Clark, Paul C.; Glover, Simon C. O.; Smith, Rowan J.; Greif, Thomas H.; Klessen, Ralf S.; Bromm, Volker
2010-11-01
We study the formation and evolution of the protostellar discs that form around the first stars in the Universe. Using sink particles, we replace the gravitationally bound gas at densities higher than 1015 cm-3 and radii greater than 3 AU from the central protostellar core, with an accreting point mass that is able to gravitationally interact with the surrounding gas. We find the disc is gravitationally (or `Toomre') unstable, and is dominated by a strong m = 2 spiral mode. Although the angular momentum transport is dominated by a combination of gravitational torques and Reynolds stresses, which are extremely efficient mechanisms, the disc is unable to process the infalling material and grows increasingly gravitationally unstable. During the build-up of the disc, the temperature in the gas is regulated by a combination of H2 line cooling, collision-induced emission and H2 dissociation, which together help to offset heating from the gravitational collapse and feedback from the protostar. Once the disc starts to fragment, H2 dissociation keeps the gas almost isothermal as the collapse of the fragment progresses. The fragmentation occurs when the protostar/disc system is only 230 yr old and at a distance of ~20 AU from its sibling, by which point the central protostar has a mass of ~1 Msolar. Given the angular momentum of the new protostellar system, it is likely that the protostars will grow to become a massive binary system.
On the diversity and statistical properties of protostellar discs
NASA Astrophysics Data System (ADS)
Bate, Matthew R.
2018-04-01
We present results from the first population synthesis study of protostellar discs. We analyse the evolution and properties of a large sample of protostellar discs formed in a radiation hydrodynamical simulation of star cluster formation. Due to the chaotic nature of the star formation process, we find an enormous diversity of young protostellar discs, including misaligned discs, and discs whose orientations vary with time. Star-disc interactions truncate discs and produce multiple systems. Discs may be destroyed in dynamical encounters and/or through ram-pressure stripping, but reform by later gas accretion. We quantify the distributions of disc mass and radii for protostellar ages up to ≈105 yr. For low-mass protostars, disc masses tend to increase with both age and protostellar mass. Disc radii range from of order 10 to a few hundred au, grow in size on time-scales ≲ 104 yr, and are smaller around lower mass protostars. The radial surface density profiles of isolated protostellar discs are flatter than the minimum mass solar nebula model, typically scaling as Σ ∝ r-1. Disc to protostar mass ratios rarely exceed two, with a typical range of Md/M* = 0.1-1 to ages ≲ 104 yr and decreasing thereafter. We quantify the relative orientation angles of circumstellar discs and the orbit of bound pairs of protostars, finding a preference for alignment that strengths with decreasing separation. We also investigate how the orientations of the outer parts of discs differ from the protostellar and inner disc spins for isolated protostars and pairs.
Trapping of low-mass planets outside the truncated inner edges of protoplanetary discs
NASA Astrophysics Data System (ADS)
Miranda, Ryan; Lai, Dong
2018-02-01
We investigate the migration of a low-mass (≲10 M⊕) planet near the inner edge of a protoplanetary disc using two-dimensional viscous hydrodynamics simulations. We employ an inner boundary condition representing the truncation of the disc at the stellar corotation radius. As described by Tsang, wave reflection at the inner disc boundary modifies the Type I migration torque on the planet, allowing migration to be halted before the planet reaches the inner edge of the disc. For low-viscosity discs (α ≲ 10-3), planets may be trapped with semi-major axes as large as three to five times the inner disc radius. In general, planets are trapped closer to the inner edge as either the planet mass or the disc viscosity parameter α increases, and farther from the inner edge as the disc thickness is increased. This planet trapping mechanism may impact the formation and migration history of close-in compact multiplanet systems.
Television animation store: Recording pictures on a parallel transfer magnetic disc
NASA Astrophysics Data System (ADS)
Durey, A. J.
1984-12-01
The recording and replaying of digital video signals using a computer-type magnetic disc-drive as part of an electronic rostrum camera animation system is described. The system was developed to enable picture sequences to be generated directly as television signals, instead of using cine film. The characteristics of the disc-drive are described together with data processing, error protection and signal synchronization systems, which enable digital television YUV component signals, sampled at 12 MHz, 4 MHz and 4 MHz respectively, to be recorded and replayed in real time.
Fisher, K; Phillips, C A
2006-12-01
To investigate the effectiveness of oils and vapours of lemon (Citrus limon), sweet orange (Citrus sinensis) and bergamot (Citrus bergamia) and their components against a number of common foodborne pathogens. The disc diffusion method was used to screen the oils and vapours against Listeria monocytogenes, Staphylococcus aureus, Bacillus cereus, Escherichia coli O157 and Campylobacter jejuni. The survival of each species, demonstrated to be susceptible in the in vitro studies, was tested on cabbage leaf for 60 s by direct contact and on chicken skin for 10 min by direct contact and 24 h by vapour. The results indicate that bergamot was the most inhibitory essential oil (EO) and citral and linalool mimicked its effect (P > 0.001). Citral and linalool vapours produced 6 log reductions in L. monocytogenes, Staph. aureus and B. cereus populations on cabbage leaf after 8-10 h exposure but bergamot vapour exposure, while producing a similar reduction in L. monocytogenes and B. cereus populations, had no effect on Staph. aureus. Bergamot was the most effective of the oils tested and linalool the most effective anti-bacterial component. Gram-positive bacteria were more susceptible than Gram-negative bacteria in vitro, although Camp. jejuni and E. coli O157 were inhibited by bergamot and linalool oils and by linalool vapour. All bacteria tested were less susceptible in food systems than in vitro. Of the Gram-positive bacteria tested Staph. aureus was the least susceptible to both the oils and the components tested. Results suggest the possibility that citrus EOs, particularly bergamot, could be used as a way of combating the growth of common causes of food poisoning.
Sánchez Pérez, A; Honrubia López, F M; Larrosa Poves, J M; Polo Llorens, V; Melcon Sánchez-Frieras, B
2001-09-01
To develop a lens planimetry technique for the optic disc using AutoCAD. To determine variability magnitude of the optic disc morphological measurements. We employed AutoCAD R.14.0 Autodesk: image acquisition, contour delimitation by multiple lines fitting or ellipse adjustment, image sectorialization and measurements quantification (optic disc and excavation, vertical diameters, optic disc area, excavation area, neuroretinal sector area and Beta atrophy area). Intraimage or operator and interimage o total reproducibility was studied by coefficient of variability (CV) (n=10) in normal and myopic optic discs. This technique allows to obtain optic disc measurement in 5 to 10 minutes time. Total or interimage variability of measurements introduced by one observer presents CV range from 1.18-4.42. Operator or intraimage measurement presents CV range from 0.30-4.21. Optic disc contour delimitation by ellipse adjustment achieved better reproducibility results than multiple lines adjustment in all measurements. Computer assisted AutoCAD planimetry is an interactive method to analyse the optic disc, feasible to incorporate to clinical practice. Reproducibility results are comparable to other analyzers in quantification optic disc morphology. Ellipse adjustment improves results in optic disc contours delimitation.
Yue, James J; Garcia, Rolando; Miller, Larry E
2016-01-01
Degeneration of the lumbar intervertebral discs is a leading cause of chronic low back pain in adults. Treatment options for patients with chronic lumbar discogenic pain unresponsive to conservative management include total disc replacement (TDR) or lumbar fusion. Until recently, only two lumbar TDRs had been approved by the US Food and Drug Administration − the Charité Artificial Disc in 2004 and the ProDisc-L Total Disc Replacement in 2006. In June 2015, a next-generation lumbar TDR received Food and Drug Administration approval − the activL® Artificial Disc (Aesculap Implant Systems). Compared to previous-generation lumbar TDRs, the activL® Artificial Disc incorporates specific design enhancements that result in a more precise anatomical match and allow a range of motion that better mimics the healthy spine. The results of mechanical and clinical studies demonstrate that the activL® Artificial Disc results in improved mechanical and clinical outcomes versus earlier-generation artificial discs and compares favorably to lumbar fusion. The purpose of this report is to describe the activL® Artificial Disc including implant characteristics, intended use, surgical technique, postoperative care, mechanical testing, and clinical experience to date. PMID:27274317
Dancing with the stars: formation of the Fomalhaut triple system and its effect on the debris discs
NASA Astrophysics Data System (ADS)
Shannon, Andrew; Clarke, Cathie; Wyatt, Mark
2014-07-01
Fomalhaut is a triple system, with all components widely separated (˜105 au). Such widely separated binaries are thought to form during cluster dissolution, but that process is unlikely to form such a triple system. We explore an alternative scenario, where A and C form as a tighter binary from a single molecular cloud core (with semimajor axis ˜104 au), and B is captured during cluster dispersal. We use N-body simulations augmented with the Galactic tidal forces to show that such a system naturally evolves into a Fomalhaut-like system in about half of cases, on a time-scale compatible with the age of Fomalhaut. From initial non-interacting orbits, Galactic tides drive cycles in B's eccentricity that lead to a close encounter with C. After several close encounters, typically lasting tens of millions of years, one of the stars is ejected. The Fomalhaut-like case with both components at large separations is almost invariably a precursor to the ejection of one component, most commonly Fomalhaut C. By including circumstellar debris in a subset of the simulations, we also show that such an evolution usually does not disrupt the coherently eccentric debris disc around Fomalhaut A, and in some cases can even produce such a disc. We also find that the final eccentricity of the disc around A and the disc around C are correlated, which may indicate that the dynamics of the three stars stirred C's disc, explaining its unusual brightness.
Yu, Yan; Mao, Haiqing; Li, Jing-Sheng; Tsai, Tsung-Yuan; Cheng, Liming; Wood, Kirkham B.; Li, Guoan; Cha, Thomas D.
2017-01-01
While abnormal loading is widely believed to cause cervical spine disc diseases, in vivo cervical disc deformation during dynamic neck motion has not been well delineated. This study investigated the range of cervical disc deformation during an in vivo functional flexion–extension of the neck. Ten asymptomatic human subjects were tested using a combined dual fluoroscopic imaging system (DFIS) and magnetic resonance imaging (MRI)-based three-dimensional (3D) modeling technique. Overall disc deformation was determined using the changes of the space geometry between upper and lower endplates of each intervertebral segment (C3/4, C4/5, C5/6, and C6/7). Five points (anterior, center, posterior, left, and right) of each disc were analyzed to examine the disc deformation distributions. The data indicated that between the functional maximum flexion and extension of the neck, the anterior points of the discs experienced large changes of distraction/compression deformation and shear deformation. The higher level discs experienced higher ranges of disc deformation. No significant difference was found in deformation ranges at posterior points of all the discs. The data indicated that the range of disc deformation is disc level dependent and the anterior region experienced larger changes of deformation than the center and posterior regions, except for the C6/7 disc. The data obtained from this study could serve as baseline knowledge for the understanding of the cervical spine disc biomechanics and for investigation of the biomechanical etiology of disc diseases. These data could also provide insights for development of motion preservation surgeries for cervical spine. PMID:28334358
Yu, Yan; Mao, Haiqing; Li, Jing-Sheng; Tsai, Tsung-Yuan; Cheng, Liming; Wood, Kirkham B; Li, Guoan; Cha, Thomas D
2017-06-01
While abnormal loading is widely believed to cause cervical spine disc diseases, in vivo cervical disc deformation during dynamic neck motion has not been well delineated. This study investigated the range of cervical disc deformation during an in vivo functional flexion-extension of the neck. Ten asymptomatic human subjects were tested using a combined dual fluoroscopic imaging system (DFIS) and magnetic resonance imaging (MRI)-based three-dimensional (3D) modeling technique. Overall disc deformation was determined using the changes of the space geometry between upper and lower endplates of each intervertebral segment (C3/4, C4/5, C5/6, and C6/7). Five points (anterior, center, posterior, left, and right) of each disc were analyzed to examine the disc deformation distributions. The data indicated that between the functional maximum flexion and extension of the neck, the anterior points of the discs experienced large changes of distraction/compression deformation and shear deformation. The higher level discs experienced higher ranges of disc deformation. No significant difference was found in deformation ranges at posterior points of all the discs. The data indicated that the range of disc deformation is disc level dependent and the anterior region experienced larger changes of deformation than the center and posterior regions, except for the C6/7 disc. The data obtained from this study could serve as baseline knowledge for the understanding of the cervical spine disc biomechanics and for investigation of the biomechanical etiology of disc diseases. These data could also provide insights for development of motion preservation surgeries for cervical spine.
ALMA observations of the multiplanet system 61 Vir: what lies outside super-Earth systems?
NASA Astrophysics Data System (ADS)
Marino, S.; Wyatt, M. C.; Kennedy, G. M.; Holland, W.; Matrà, L.; Shannon, A.; Ivison, R. J.
2017-08-01
A decade of surveys has hinted at a possible higher occurrence rate of debris discs in systems hosting low-mass planets. This could be due to common favourable forming conditions for rocky planets close in and planetesimals at large radii. In this paper, we present the first resolved millimetre study of the debris disc in the 4.6 Gyr old multiplanet system 61 Vir, combining Atacama Large Millimeter/submillimeter Array and James Clerk Maxwell Telescope data at 0.86 mm. We fit the data using a parametric disc model, finding that the disc of planetesimals extends from 30 au to at least 150 au, with a surface density distribution of millimetre-sized grains with a power-law slope of 0.1^{+1.1}_{-0.8}. We also present a numerical collisional model that can predict the evolution of the surface density of millimetre grains for a given primordial disc, finding that it does not necessarily have the same radial profile as the total mass surface density (as previous studies suggested for the optical depth), with the former being flatter. Finally, we find that if the planetesimal disc was stirred at 150 au by an additional unseen planet, that planet should be more massive than 10 M⊕ and lie between 10 and 20 au. Lower planet masses and semimajor axes down to 4 au are possible for eccentricities ≫0.1.
Salamat, Sara; Hutchings, John; Kwong, Clemens; Magnussen, John; Hancock, Mark J
2016-01-01
To assess the relationship between quantitative measures of disc height and signal intensity with the Pfirrmann disc degeneration scoring system and to test the inter-rater reliability of the quantitative measures. Participants were 76 people who had recently recovered from their last episode of acute low back pain and underwent MRI scan on a single 3T machine. At all 380 lumbar discs, quantitative measures of disc height and signal intensity were made by 2 independent raters and compared to Pfirrmann scores from a single radiologist. For quantitative measures of disc height and signal intensity a "raw" score and 2 adjusted ratios were calculated and the relationship with Pfirrmann scores was assessed. The inter-tester reliability of quantitative measures was also investigated. There was a strong linear relationship between quantitative disc signal intensity and Pfirrmann scores for grades 1-4, but not for grades 4 and 5. For disc height only, Pfirrmann grade 5 had significantly reduced disc height compared to all other grades. Results were similar regardless of whether raw or adjusted scores were used. Inter-rater reliability for the quantitative measures was excellent (ICC > 0.97). Quantitative measures of disc signal intensity were strongly related to Pfirrmann scores from grade 1 to 4; however disc height only differentiated between grade 4 and 5 Pfirrmann scores. Using adjusted ratios for quantitative measures of disc height or signal intensity did not significantly alter the relationship with Pfirrmann scores.
Alignment in star-debris disc systems seen by Herschel
NASA Astrophysics Data System (ADS)
Greaves, J. S.; Kennedy, G. M.; Thureau, N.; Eiroa, C.; Marshall, J. P.; Maldonado, J.; Matthews, B. C.; Olofsson, G.; Barlow, M. J.; Moro-Martín, A.; Sibthorpe, B.; Absil, O.; Ardila, D. R.; Booth, M.; Broekhoven-Fiene, H.; Brown, D. J. A.; Cameron, A. Collier; del Burgo, C.; Di Francesco, J.; Eislöffel, J.; Duchêne, G.; Ertel, S.; Holland, W. S.; Horner, J.; Kalas, P.; Kavelaars, J. J.; Lestrade, J.-F.; Vican, L.; Wilner, D. J.; Wolf, S.; Wyatt, M. C.
2014-02-01
Many nearby main-sequence stars have been searched for debris using the far-infrared Herschel satellite, within the DEBRIS, DUNES and Guaranteed-Time Key Projects. We discuss here 11 stars of spectral types A-M where the stellar inclination is known and can be compared to that of the spatially resolved dust belts. The discs are found to be well aligned with the stellar equators, as in the case of the Sun's Kuiper belt, and unlike many close-in planets seen in transit surveys. The ensemble of stars here can be fitted with a star-disc tilt of ≲ 10°. These results suggest that proposed mechanisms for tilting the star or disc in fact operate rarely. A few systems also host imaged planets, whose orbits at tens of au are aligned with the debris discs, contrary to what might be expected in models where external perturbers induce tilts.
Breaking mean-motion resonances during Type I planet migration
NASA Astrophysics Data System (ADS)
Hands, T. O.; Alexander, R. D.
2018-03-01
We present 2D hydrodynamical simulations of pairs of planets migrating simultaneously in the Type I regime in a protoplanetary disc. Convergent migration naturally leads to the trapping of these planets in mean-motion resonances. Once in resonance the planets' eccentricity grows rapidly, and disc-planet torques cause the planets to escape resonance on a time-scale of a few hundred orbits. The effect is more pronounced in highly viscous discs, but operates efficiently even in inviscid discs. We attribute this resonance-breaking to overstable librations driven by moderate eccentricity damping, but find that this mechanism operates differently in hydrodynamic simulations than in previous analytic calculations. Planets escaping resonance in this manner can potentially explain the observed paucity of resonances in Kepler multitransiting systems, and we suggest that simultaneous disc-driven migration remains the most plausible means of assembling tightly packed planetary systems.
Mishra, Amita; Sharma, Amit Kumar; Kumar, Shashank; Saxena, Ajit K; Pandey, Abhay K
2013-01-01
The present study reports the phytochemical profiling, antimicrobial, antioxidant, and anticancer activities of Bauhinia variegata leaf extracts. The reducing sugar, anthraquinone, and saponins were observed in polar extracts, while terpenoids and alkaloids were present in nonpolar and ethanol extracts. Total flavonoid contents in various extracts were found in the range of 11-222.67 mg QE/g. In disc diffusion assays, petroleum ether and chloroform fractions exhibited considerable inhibition against Klebsiella pneumoniae. Several other extracts also showed antibacterial activity against pathogenic strains of E. coli, Proteus spp. and Pseudomonas spp. Minimum bactericidal concentration (MBC) values of potential extracts were found between 3.5 and 28.40 mg/mL. The lowest MBC (3.5 mg/mL) was recorded for ethanol extract against Pseudomonas spp. The antioxidant activity of the extracts was compared with standard antioxidants. Dose dependent response was observed in reducing power of extracts. Polar extracts demonstrated appreciable metal ion chelating activity at lower concentrations (10-40 μg/mL). Many extracts showed significant antioxidant response in beta carotene bleaching assay. AQ fraction of B. variegata showed pronounced cytotoxic effect against DU-145, HOP-62, IGR-OV-1, MCF-7, and THP-1 human cancer cell lines with 90-99% cell growth inhibitory activity. Ethyl acetate fraction also produced considerable cytotoxicity against MCF-7 and THP-1 cell lines. The study demonstrates notable antibacterial, antioxidant, and anticancer activities in B. variegata leaf extracts.
Recent Developments in Interactive and Communicative CALL: Hypermedia and "Intelligent" Systems.
ERIC Educational Resources Information Center
Coughlin, Josette M.
Two recent developments in computer-assisted language learning (CALL), interactive video systems and "intelligent" games, are discussed. Under the first heading, systems combining the use of a computer and video disc player are described, and Compact Discs Interactive (CDI) and Digital Video Interactive (DVI) are reviewed. The…
Exact density-potential pairs from complex-shifted axisymmetric systems
NASA Astrophysics Data System (ADS)
Ciotti, Luca; Marinacci, Federico
2008-07-01
In a previous paper, the complex-shift method has been applied to self-gravitating spherical systems, producing new analytical axisymmetric density-potential pairs. We now extend the treatment to the Miyamoto-Nagai disc and the Binney logarithmic halo, and we study the resulting axisymmetric and triaxial analytical density-potential pairs; we also show how to obtain the surface density of shifted systems from the complex shift of the surface density of the parent model. In particular, the systems obtained from Miyamoto-Nagai discs can be used to describe disc galaxies with a peanut-shaped bulge or with a central triaxial bar, depending on the direction of the shift vector. By using a constructive method that can be applied to generic axisymmetric systems, we finally show that the Miyamoto-Nagai and the Satoh discs, and the Binney logarithmic halo cannot be obtained from the complex shift of any spherical parent distribution. As a by-product of this study, we also found two new generating functions in closed form for even and odd Legendre polynomials, respectively.
The formation of co-orbital planets and their resulting transit signatures
NASA Astrophysics Data System (ADS)
Granados Contreras, Agueda Paula; Boley, Aaron
2018-04-01
Systems with Tightly-packed Inner Planets (STIPs) are metastable, exhibiting sudden transitions to an unstable state that can potentially lead to planet consolidation. When these systems are embedded in a gaseous disc, planet-disc interactions can significantly reduce the frequency of instabilities, and if they do occur, disc torques alter the dynamical outcomes. We ran a suite of N-body simulations of synthetic 6-planet STIPs using an independent implementation of IAS15 that includes a prescription for gaseous tidal damping. The algorithm is based on the results of disc simulations that self-consistently evolve gas and planets. Even for very compact configurations, the STIPS are resistant to instability when gas is present. However, instability can still occur, and in some cases, the combination of system instability and gaseous damping leads to the formation of co-orbiting planets that are stable even when gas damping is removed. While rare, such systems should be detectable in transit surveys, although the dynamics of the system can make the transit signature difficult to identify.
Gebhard, Harry; James, Andrew R.; Bowles, Robby D.; Dyke, Jonathan P.; Saleh, Tatianna; Doty, Stephen P.; Bonassar, Lawrence J.; Härtl, Roger
2011-01-01
Study design: Prospective randomized animal study. Objective: To determine a surgical technique for reproducible and functional intervertebral disc replacement in an orthotopic animal model. Methods: The caudal 3/4 intervertebral disc (IVD) of the rat tail was approached by two surgical techniques: blunt dissection, stripping and retracting (Technique 1) or incising and repairing (Technique 2) the dorsal longitudinal tendons. The intervertebral disc was dissected and removed, and then either discarded or reinserted. Outcome measures were perioperative complications, spontaneous tail movement, 7T MRI (T1- and T2-sequences for measurement of disc space height (DSH) and disc hydration). Microcomputed tomographic imaging (micro CT) was additionally performed postmortem. Results: No vascular injuries occurred and no systemic or local infections were observed over the course of 1 month. Tail movements were maintained. With tendon retraction (Technique 1) gross loss of DSH occurred with both discectomy and reinsertion. Tendon division (Technique 2) maintained DSH with IVD reinsertion but not without. The DSH was demonstrated on MRI measurement. A new scoring system to assess IVD appearances was described. Conclusions: The rat tail model, with a tendon dividing surgical technique, can function as an orthotopic animal model for IVD research. Mechanical stimulation is maintained by preserved tail movements. 7T MRI is a feasible modality for longitudinal monitoring for the rat caudal disc. PMID:22956934
Optical excess of dim isolated neutron stars
NASA Astrophysics Data System (ADS)
Ertan, Ü.; Çalışkan, Ş.; Alpar, M. A.
2017-09-01
The optical excess in the spectra of dim isolated neutron stars (XDINs) is a significant fraction of their rotational energy loss rate. This is strikingly different from the situation in isolated radio pulsars. We investigate this problem in the framework of the fallback disc model. The optical spectra can be powered by magnetic stresses on the innermost disc matter, as the energy dissipated is emitted as blackbody radiation mainly from the inner rim of the disc. In the fallback disc model, XDINs are the sources evolving in the propeller phase with similar torque mechanisms. In this model, the ratio of the total magnetic work that heats up the inner disc matter is expected to be similar for different XDINs. Optical luminosities that are calculated consistently with the optical spectra and the theoretical constraints on the inner disc radii give very similar ratios of the optical luminosity to the rotational energy loss rate for all these sources. These ratios indicate that a significant fraction of the magnetic torque heats up the disc matter while the remaining fraction expels disc matter from the system. For XDINs, the contribution of heating by X-ray irradiation to the optical luminosity is negligible in comparison with the magnetic heating. The correlation we expect between the optical luminosities and the rotational energy loss rates of XDINs can be a property of the systems with low X-ray luminosities, in particular those in the propeller phase.
A flickering study of nova-like systems KR Aur and UU Aqr
NASA Astrophysics Data System (ADS)
Dobrotka, A.; Mineshige, S.; Casares, J.
2012-03-01
We present a study of the flickering activity in two nova-like systems, KR Aur and UU Aqr. We applied a statistical model of flickering simulations in accretion discs based on turbulent angular momentum transport between two adjacent rings with an exponential distribution of the turbulence dimension scale. The model is based on a steady-state disc model, which is satisfied in the case of hot ionized discs of nova-like cataclysmic variables. Our model successfully fits the observed power-density spectrum of KR Aur with the disc parameter α= 0.10-0.40 and an inner-disc truncation radius in the range Rin= 0.88-1.67 × 109 cm. The exact values depend on the mass-transfer rate in the sense that α decreases and Rin increases with mass-transfer rate. In any case, the inner-disc radius found for KR Aur is considerably smaller than those for quiescent dwarf novae, as predicted by the disc instability model. On the other hand, our simulations fail to reproduce the power-density spectrum of UU Aqr. A tantalizing explanation involves the possible presence of spiral waves, which are expected in UU Aqr because of its low mass ratio but not in KR Aur. In general our model predicts the observed concentration of flickering in the central disc. We explain this by the radial dependence of the angular-momentum gradient.
High-density near-field optical disc recording using phase change media and polycarbonate substrate
NASA Astrophysics Data System (ADS)
Shinoda, Masataka; Saito, Kimihiro; Ishimoto, Tsutomu; Kondo, Takao; Nakaoki, Ariyoshi; Furuki, Motohiro; Takeda, Minoru; Akiyama, Yuji; Shimouma, Takashi; Yamamoto, Masanobu
2004-09-01
We developed a high density near field optical recording disc system with a solid immersion lens and two laser sources. In order to realize the near field optical recording, we used a phase change recording media and a molded polycarbonate substrate. The near field optical pick-up consists of a solid immersion lens with numerical aperture of 1.84. The clear eye pattern of 90.2 GB capacity (160nm track pitch and 62 nm per bit) was observed. The jitter using a limit equalizer was 10.0 % without cross-talk. The bit error rate using an adaptive PRML with 8 taps was 3.7e-6 without cross-talk. We confirmed that the near field optical disc system is a promising technology for a next generation high density optical disc system.
Ladhari, Afef; Laarif, Asma; Omezzine, Faten; Haouala, Rabiaa
2013-01-01
Aqueous and organic (hexane, chloroform, and methanol) extracts of siliquae, stems and leaves, and seeds of Cleome arabica L. (Brassicales: Capparidaceae) were evaluated in the laboratory for their antifeeding and insecticidal effect on larvae of the cotton leafworm, Spodoptera littoralis (Boisduval) (Lepidoptera, Noctuidae), using a leaf dipping bioassay with castor bean, Ricinus communis L. (Malpighiales: Euphorbiaceae), leaf discs. The polar extracts caused significant mortality. At the highest dose, C. arabica extracts exhibited significant antifeeding and phagostimulating activities against S. littoralis larvae. Under no-choice conditions, the methanol extract of siliquae was the most active, and the antifeedant index calculated over 24 hr for 3rd instar larvae varied significantly from 16 to 37%. Using nutritional indices, it was established that there was a significant decrease in growth rate concomitant with a reduction in consumption. These results suggest the presence of anti-feeding and/or toxic substances in the extracts that may be useful in developing bio-insecticides based on C. arabica extracts for use in integrated pest management of leafworm and other agricultural pests. PMID:23906290
Using and Developing with CD-Interactive: Frequently Asked Questions Are Answered.
ERIC Educational Resources Information Center
Lediaev, Lucy; van Sonderen, Lex
1994-01-01
Discusses Compact Disc-Interactive (CD-I) using a question-and-answer format. Highlights include development of the CD-I technology; where to purchase discs and players; compatibility with other CD-ROM drives; how to make discs; authoring systems versus custom programs; entertainment and educational applications; licensing issues; specifications;…
The Reading Disc: Learning to Read Using Interactive CD.
ERIC Educational Resources Information Center
Shaw, Simon
1991-01-01
Describes the development of an interactive compact disc on CD-ROM XA that was designed to help adults learn to read. The application of technology to learning is discussed, differences in learner control in computer-based systems are considered, virtual writing is described, and assessment activities available on the disc are explained. (five…
Marini, Giacomo; Studer, Harald; Huber, Gerd; Püschel, Klaus; Ferguson, Stephen J
2016-06-01
Patient-specific modelling of the spine is a powerful tool to explore the prevention and the treatment of injuries and pathologies. Albeit several methods have been proposed for the discretization of the bony structures, the efficient representation of the intervertebral disc anisotropy remains a challenge, especially with complex geometries. Furthermore, the swelling of the disc's nucleus pulposus is normally added to the model after geometry definition, at the cost of changes of the material properties and an unrealistic description of the prestressed state. The aim of this study was to develop techniques, which preserve the patient-specific geometry of the disc and allow the representation of the system anisotropy and residual stresses, independent of the system discretization. Depending on the modelling features, the developed approaches resulted in a response of patient-specific models that was in good agreement with the physiological response observed in corresponding experiments. The proposed methods represent a first step towards the development of patient-specific models of the disc which respect both the geometry and the mechanical properties of the specific disc.
NASA Astrophysics Data System (ADS)
Molnár, Dániel Cs; Sargent, Mark T.; Delhaize, Jacinta; Delvecchio, Ivan; Smolčić, Vernesa; Novak, Mladen; Schinnerer, Eva; Zamorani, Giovanni; Bondi, Marco; Herrera-Ruiz, Noelia; Murphy, Eric J.; Vardoulaki, Eleni; Karim, Alexander; Leslie, Sarah; Magnelli, Benjamin; Carollo, C. Marcella; Middelberg, Enno
2018-03-01
Using infrared data from the Herschel Space Observatory and Karl G. Jansky Very Large Array 3 GHz observations in the COSMOS field, we investigate the redshift evolution of the infrared-radio correlation (IRRC) for star-forming galaxies (SFGs) we classify as either spheroid- or disc-dominated based on their morphology. The sample predominantly consists of disc galaxies with stellar mass ≳ 1010 M⊙, and residing on the star-forming main sequence (MS). After the removal of AGN using standard approaches, we observe a significant difference between the redshift evolution of the median IR/radio ratio \\overline{q}_{TIR} of (i) a sample of ellipticals, plus discs with a substantial bulge component (`spheroid-dominated' SFGs) and, (ii) virtually pure discs and irregular systems (`disc-dominated' SFGs). The spheroid-dominated population follows a declining \\overline{q}_{TIR} versus z trend similar to that measured in recent evolutionary studies of the IRRC. However, for disc-dominated galaxies, where radio and IR emission should be linked to star formation in the most straightforward way, we measure very little change in \\overline{q}_{TIR}. This suggests that low-redshift calibrations of radio emission as a star formation rate (SFR) tracer may remain valid out to at least z ≃ 1-1.5 for pure star-forming systems. We find that the different redshift evolution of qTIR for the spheroid- and disc-dominated sample is mainly due to an increasing radio excess for spheroid-dominated galaxies at z ≳ 0.8, hinting at some residual AGN activity in these systems. This finding demonstrates that in the absence of AGN, the IRRC is independent of redshift, and that radio observations can therefore be used to estimate SFRs at all redshifts for genuinely star-forming galaxies.
Formation of precessing jets by tilted black hole discs in 3D general relativistic MHD simulations
NASA Astrophysics Data System (ADS)
Liska, M.; Hesp, C.; Tchekhovskoy, A.; Ingram, A.; van der Klis, M.; Markoff, S.
2018-02-01
Gas falling into a black hole (BH) from large distances is unaware of BH spin direction, and misalignment between the accretion disc and BH spin is expected to be common. However, the physics of tilted discs (e.g. angular momentum transport and jet formation) is poorly understood. Using our new GPU-accelerated code H-AMR, we performed 3D general relativistic magnetohydrodynamic simulations of tilted thick accretion discs around rapidly spinning BHs, at the highest resolution to date. We explored the limit where disc thermal pressure dominates magnetic pressure, and showed for the first time that, for different magnetic field strengths on the BH, these flows launch magnetized relativistic jets propagating along the rotation axis of the tilted disc (rather than of the BH). If strong large-scale magnetic flux reaches the BH, it bends the inner few gravitational radii of the disc and jets into partial alignment with the BH spin. On longer time-scales, the simulated disc-jet system as a whole undergoes Lense-Thirring precession and approaches alignment, demonstrating for the first time that jets can be used as probes of disc precession. When the disc turbulence is well resolved, our isolated discs spread out, causing both the alignment and precession to slow down.
Extended transiting discs and rings around planets and brown dwarfs: theoretical constraints
NASA Astrophysics Data System (ADS)
Zanazzi, J. J.; Lai, Dong
2017-02-01
Newly formed planets (or brown dwarfs) may possess discs or rings which occupy an appreciable fraction of the planet's Hill sphere and extend beyond the Laplace radius, where the tidal torque from the host star dominates over the torque from the oblate planet. Such a disc/ring can exhibit unique, detectable transit signatures, provided that the disc/ring is significantly misaligned with the orbital plane of the planet. There exists tentative evidence for an extended ring system around the young K5 star 1 SWASP J140747-354542. We present a general theoretical study of the inclination (warp) profile of circumplanetary discs under the combined influences of the tidal torque from the central star, the torque from the oblate planet, and the self-gravity of the disc. We calculate the equilibrium warp profile (`generalized Laplace surface') and investigate the condition for coherent precession of the disc. We find that to maintain a non-negligible misalignment between the extended outer disc and the planet's orbital plane, and to ensure coherent disc precession, the disc surface density must be sufficiently large so that the self-gravity torque overcomes the tidal torque from the central star. Our analysis and quantitative results can be used to constrain the parameters of transiting circumplanetary discs which may be detected in the future.
Senescent intervertebral disc cells exhibit perturbed matrix homeostasis phenotype.
Ngo, Kevin; Patil, Prashanti; McGowan, Sara J; Niedernhofer, Laura J; Robbins, Paul D; Kang, James; Sowa, Gwendolyn; Vo, Nam
2017-09-01
Aging greatly increases the risk for intervertebral disc degeneration (IDD) as a result of proteoglycan loss due to reduced synthesis and enhanced degradation of the disc matrix proteoglycan (PG). How disc matrix PG homeostasis becomes perturbed with age is not known. The goal of this study is to determine whether cellular senescence is a source of this perturbation. We demonstrated that disc cellular senescence is dramatically increased in the DNA repair-deficient Ercc1 -/Δ mouse model of human progeria. In these accelerated aging mice, increased disc cellular senescence is closely associated with the rapid loss of disc PG. We also directly examine PG homeostasis in oxidative damage-induced senescent human cells using an in vitro cell culture model system. Senescence of human disc cells treated with hydrogen peroxide was confirmed by growth arrest, senescence-associated β-galactosidase activity, γH2AX foci, and acquisition of senescence-associated secretory phenotype. Senescent human disc cells also exhibited perturbed matrix PG homeostasis as evidenced by their decreased capacity to synthesize new matrix PG and enhanced degradation of aggrecan, a major matrix PG. of the disc. Our in vivo and in vitro findings altogether suggest that disc cellular senescence is an important driver of PG matrix homeostatic perturbation and PG loss. Published by Elsevier B.V.
Documentation of pharmaceutical care: Validation of an intervention oriented classification system.
Maes, Karen A; Studer, Helene; Berger, Jérôme; Hersberger, Kurt E; Lampert, Markus L
2017-12-01
During the dispensing process, pharmacists may come across technical and clinical issues requiring a pharmaceutical intervention (PI). An intervention-oriented classification system is a helpful tool to document these PIs in a structured manner. Therefore, we developed the PharmDISC classification system (Pharmacists' Documentation of Interventions in Seamless Care). The aim of this study was to evaluate the PharmDISC system in the daily practice environment (in terms of interrater reliability, appropriateness, interpretability, acceptability, feasibility, and validity); to assess its user satisfaction, the descriptive manual, and the online training; and to explore first implementation aspects. Twenty-one pharmacists from different community pharmacies each classified 30 prescriptions requiring a PI with the PharmDISC system on 5 selected days within 5 weeks. Interrater reliability was determined using model PIs and Fleiss's kappa coefficients (κ) were calculated. User satisfaction was assessed by questionnaire with a 4-point Likert scale. The main outcome measures were interrater reliability (κ); appropriateness, interpretability, validity (ratio of completely classified PIs/all PIs); feasibility, and acceptability (user satisfaction and suggestions). The PharmDISC system reached an average substantial agreement (κ = 0.66). Of documented 519 PIs, 430 (82.9%) were completely classified. Most users found the system comprehensive (median user agreement 3 [2/3.25 quartiles]) and practical (3[2.75/3]). The PharmDISC system raised the awareness regarding drug-related problems for most users (n = 16). To facilitate its implementation, an electronic version that automatically connects to the prescription together with a task manager for PIs needing follow-up was suggested. Barriers could be time expenditure and lack of understanding the benefits. Substantial interrater reliability and acceptable user satisfaction indicate that the PharmDISC system is a valid system to document PIs in daily community pharmacy practice. © 2017 John Wiley & Sons, Ltd.
An Automatic Lab-on-Disc System for Blood Typing.
Chang, Yaw-Jen; Fan, Yi-Hua; Chen, Shia-Chung; Lee, Kuan-Hua; Lou, Liao-Yong
2018-04-01
A blood-typing assay is a critical test to ensure the serological compatibility of a donor and an intended recipient prior to a blood transfusion. This article presents a lab-on-disc blood-typing system to conduct a total of eight assays for a patient, including forward-typing tests, reverse-typing tests, and irregular-antibody tests. These assays are carried out in a microfluidic disc simultaneously. A blood-typing apparatus was designed to automatically manipulate the disc. The blood type can be determined by integrating the results of red blood cell (RBC) agglutination in the microchannels. The experimental results of our current 40 blood samples show that the results agree with those examined in the hospital. The accuracy reaches 97.5%.
1RXS J180834.7+101041 is a new cataclysmic variable with non-uniform disc
NASA Astrophysics Data System (ADS)
Yakin, D. G.; Suleimanov, V. F.; Shimansky, V. V.; Borisov, N. V.; Bikmaev, I. F.; Sakhibullin, N. A.
2010-11-01
Results of photometric and spectroscopic investigations of the recently discovered disc cataclysmic variable star 1RXS J180834.7+101041 are presented. Emission spectra of the system show broad double peaked hydrogen and helium emission lines. Doppler maps for the hydrogen lines demonstrate strongly non-uniform emissivity distribution in the disc, similar to that found in IP Peg. It means that the system is a new cataclysmic variable with a spiral density wave in the disc. Masses of the components (MWD = 0.8+/-0.22 Msolar and MRD = 0.14+/-0.02 Msolar), and the orbit inclination (i = 78°+/- 1.°5) were estimated using the various well-known relations for cataclysmic variables.
Rees, Robert C; McArdle, Stephanie; Mian, Shahid; Li, Geng; Ahmad, Murrium; Parkinson, Richard; Ali, Selman A
2002-02-01
Disabled infectious single cycle-herpes simplex viruses (DISC-HSV) have been shown to be safe for use in humans and may be considered efficacious as vectors for immunogene therapy in cancer. Preclinical studies show that DISC-HSV is an efficient delivery system for cytokine genes and antigens. DISC-HSV infects a high proportion of cells, resulting in rapid gene expression for at least 72 h. The DISC-HSV-mGM-CSF vector, when inoculated into tumors, induces tumor regression in a high percentage of animals, concomitant with establishing a cytotoxic T-cell response, which is MHC class I restricted and directed against peptides of known tumor antigens. The inherent properties of DISC-HSV makes it a suitable vector for consideration in human immunogene therapy trials.
Formation of terrestrial planets in eccentric and inclined giant planet systems
NASA Astrophysics Data System (ADS)
Sotiriadis, Sotiris; Libert, Anne-Sophie; Raymond, Sean N.
2018-06-01
Aims: Evidence of mutually inclined planetary orbits has been reported for giant planets in recent years. Here we aim to study the impact of eccentric and inclined massive giant planets on the terrestrial planet formation process, and investigate whether it can possibly lead to the formation of inclined terrestrial planets. Methods: We performed 126 simulations of the late-stage planetary accretion in eccentric and inclined giant planet systems. The physical and orbital parameters of the giant planet systems result from n-body simulations of three giant planets in the late stage of the gas disc, under the combined action of Type II migration and planet-planet scattering. Fourteen two- and three-planet configurations were selected, with diversified masses, semi-major axes (resonant configurations or not), eccentricities, and inclinations (including coplanar systems) at the dispersal of the gas disc. We then followed the gravitational interactions of these systems with an inner disc of planetesimals and embryos (nine runs per system), studying in detail the final configurations of the formed terrestrial planets. Results: In addition to the well-known secular and resonant interactions between the giant planets and the outer part of the disc, giant planets on inclined orbits also strongly excite the planetesimals and embryos in the inner part of the disc through the combined action of nodal resonance and the Lidov-Kozai mechanism. This has deep consequences on the formation of terrestrial planets. While coplanar giant systems harbour several terrestrial planets, generally as massive as the Earth and mainly on low-eccentric and low-inclined orbits, terrestrial planets formed in systems with mutually inclined giant planets are usually fewer, less massive (<0.5 M⊕), and with higher eccentricities and inclinations. This work shows that terrestrial planets can form on stable inclined orbits through the classical accretion theory, even in coplanar giant planet systems emerging from the disc phase.
High-frequency transformation of Lobelia erinus L. by Agrobacterium-mediated gene transfer.
Tsugawa, H; Kagami, T; Suzuki, M
2004-05-01
A highly efficient transformation procedure was developed for Lobelia erinus. Leaf or cotyledon discs were inoculated with Agrobacterium tumefaciens strain EHA105 harboring the binary vector plasmid pIG121Hm, which contains a beta-glucuronidase gene with an intron as a reporter gene and both the neomycin phosphotransferase II and hygromycin phosphotransferase genes as selectable markers. The hygromycin-resistant calli produced on the selection medium were transferred to MS medium supplemented with 0.5 mg/l benzyladenine and 0.2 mg/l indole-3-acetic acid for regeneration of adventitious shoots. Transgenic plants were obtained as a result of the high regeneration rate of the transformed calli, which was as high as 83%. In contrast, no transgenic plant was obtained by the procedure of direct shoot formation following inoculation with A. tumefaciens. Transgenic plants flowered 3-4 months after transformation. Integration of the transgenes was detected using PCR and Southern blot analysis, which revealed that one to several copies were integrated into the genomes of the host plants. The transformation frequency at the stage of whole plants was very high--45% per inoculated disc. Copyright 2004 Springer-Verlag
SITE TECHNOLOGY CAPSULE: ROCHEM SEPARATION SYSTEMS, INC. - DISC TUBE MODULE TECHNOLOGY
SITE Program demonstration of the Rochem Disc Tube Module™(DTM) developed by Rochem Separations Systems, Inc. The demonstration test was conducted at the central landfill superfund site in Johnston, Rhode island in August, 1994. The DTM technology is an innovative membrane filt...
Blue phase-change recording at high data densities and data rates
NASA Astrophysics Data System (ADS)
Dekker, Martijn K.; Pfeffer, Nicola; Kuijper, Maarten; Ubbens, Igolt P.; Coene, Wim M. J.; Meinders, E. R.; Borg, Herman J.
2000-09-01
For the DVR system with the use of a blue laser diode (wavelength 405 nm) we developed (12 cm) discs with a total capacity of 22.4 GB. The land/groove track pitch is 0.30 micrometers and the channel bit length is 87 nm. The DVR system uses a d equals 1 code. These phase change discs can be recorded at continuous angular velocity at a maximum of 50 Mbps user data rate (including all format and ECC overhead) and meet the system specifications. Fast growth determined phase change materials (FGM) are used for the active layer. In order to apply these FGM discs at small track pitch special attention has been paid to the issue of thermal cross-write. Finally routes towards higher capacities such as advanced bit detection schemes and the use of a smaller track pitch are considered. These show the feasibility in the near future of at least 26.0 GB on a disc for the DVR system with a blue laser diode.
Alavi, Mehran; Karimi, Naser
2017-12-12
Recently, major problem related to pathogenic bacteria is augmentation of antibiotic resistance which has been changed treatment and recovery of millions of infectious patients. The present study reports an eco-friendly, rapid and easy method for synthesis of silver (Ag), copper (Cu) and titanium dioxide (TiO 2 ) nanoparticles (NPs) using Artemisia haussknechtii leaf aqueous extract with antibacterial activities against multi-drug resistance (MDR) bacteria species. Three different concentrations (0.001, 0.01 and 0.1 M) of AgNO 3 , CuSO 4 and TiO (OH) 2 were investigated for obtaining optimum NPs green synthesis. Total phenolic content, total flavonoid content of leaf extract and total antioxidant activity (DPPH) assay were determined as radical scavenging methods. UV-Visible spectroscopy, Fourier transform infrared spectroscopy analysis, X-ray diffraction, energy dispersive X-ray spectroscopy, field emission scanning electron microscope and atomic force microscopy (AFM) were used due to NPs characterization. The size average of the Ag, Cu and TiO 2 NPs obtained were respectively 10.69 ± 5.55, 35.36 ± 44.4 and 92.58 ± 56.98 nm. In the case of antibacterial assay, disc diffusion assay, minimum inhibitory concentration, minimum bactericidal concentration, bacterial growth and morphology of four MDR species Staphylococcus aureus ATCC 43300, Staphylococcus epidermidis ATCC 12258, Serratia marcescens ATTC13880 and Escherichia coli ATCC 25922 were evaluated. Results of this study demonstrated that A. haussknechtii leaf extract with various groups of phytochemicals such as phenols and flavonoids had suitable ability in green synthesis of Ag, Cu and TiO 2 NPs. Also, Ag and Cu NPs had more antibacterial activities compared to TiO 2 NPs.
Revolution evolution: tracing angular momentum during star and planetary system formation
NASA Astrophysics Data System (ADS)
Davies, Claire Louise
2015-04-01
Stars form via the gravitational collapse of molecular clouds during which time the protostellar object contracts by over seven orders of magnitude. If all the angular momentum present in the natal cloud was conserved during collapse, stars would approach rotational velocities rapid enough to tear themselves apart within just a few Myr. In contrast to this, observations of pre-main sequence rotation rates are relatively slow (∼ 1 - 15 days) indicating that significant quantities of angular momentum must be removed from the star. I use observations of fully convective pre-main sequence stars in two well-studied, nearby regions of star formation (namely the Orion Nebula Cluster and Taurus-Auriga) to determine the removal rate of stellar angular momentum. I find the accretion disc-hosting stars to be rotating at a slower rate and contain less specific angular momentum than the disc-less stars. I interpret this as indicating a period of accretion disc-regulated angular momentum evolution followed by near-constant rotational evolution following disc dispersal. Furthermore, assuming that the age spread inferred from the Hertzsprung-Russell diagram constructed for the star forming region is real, I find that the removal rate of angular momentum during the accretion-disc hosting phase to be more rapid than that expected from simple disc-locking theory whereby contraction occurs at a fixed rotation period. This indicates a more efficient process of angular momentum removal must operate, most likely in the form of an accretion-driven stellar wind or outflow emanating from the star-disc interaction. The initial circumstellar envelope that surrounds a protostellar object during the earliest stages of star formation is rotationally flattened into a disc as the star contracts. An effective viscosity, present within the disc, enables the disc to evolve: mass accretes inwards through the disc and onto the star while momentum migrates outwards, forcing the outer regions of the disc to expand. I used spatially resolved submillimetre detections of the dust and gas components of protoplanetary discs, gathered from the literature, to measure the radial extent of discs around low-mass pre-main sequence stars of ∼ 1-10 Myr and probe their viscous evolution. I find no clear observational evidence for the radial expansion of the dust component. However, I find tentative evidence for the expansion ofthe gas component. This suggests that the evolution of the gas and dust components of protoplanetary discs are likely governed by different astrophysical processes. Observations of jets and outflows emanating from protostars and pre-main sequence stars highlight that it may also be possible to remove angular momentum from the circumstellar material. Using the sample of spatially resolved protoplanetary discs, I find no evidence for angular momentum removal during disc evolution. I also use the spatially resolved debris discs from the Submillimetre Common-User Bolometer Array-2 Observations of Nearby Stars survey to constrain the amount of angular momentum retained within planetary systems. This sample is compared to the protoplanetary disc angular momenta and to the angular momentum contained within pre-stellar cores. I find that significant quantities of angular momentum must be removed during disc formation and disc dispersal. This likely occurs via magnetic braking during the formation of the disc, via the launching of a disc or photo-evaporative wind, and/or via ejection of planetary material following dynamical interactions.
Lou, Chao; Chen, Hongliang; Mei, Liangwei; Yu, Weiyang; Zhu, Kejun; Liu, Feijun; Chen, Zhenzhong; Xiang, Guangheng; Chen, Minjiang; Weng, Qiaoyou; He, Dengwei
2017-10-01
The aim of this study was to revisit and further investigate the association between menopause and disc degeneration in the lumbar spine using a magnetic resonance imaging-based eight-level grading system. This study cohort comprised of 1,566 women and 1,382 age-matched men who were admitted for low back pain from June 2013 to October 2016. Data on age, weight, height, body mass index, age at natural menopause, and years since menopause (YSM) were obtained. Lumbar disc degeneration was assessed using a magnetic resonance imaging-based eight-level grading system. After adjustment for the confounding factors of age, height, and weight, young age-matched men were more susceptible to disc degeneration than premenopausal women (P < 0.05). However, after menopause, postmenopausal women had a significant tendency to develop more severe disc degeneration than their age-matched men (P < 0.05), and also compared with premenopausal and perimenopausal women (P < 0.01). Postmenopausal women were divided into nine subgroups by every 5 YSM. When YSM was less than 15 years, a positive trend was observed between YSM and severity of disc degeneration, respectively, at L1/L2 (r = 0.241), L2/L3 (r = 0.193), L3/L4 (r = 0.191), L4/L5 (r = 0.165), L5/S1 (r = 0.153), and all lumbar discs (r = 0.237) (P < 0.05 or 0.01). The analysis of covariance indicated a significant difference in each disc level (P < 0.05 or 0.01) between every two groups. When YSM was more than 15 years, the significant difference, however, disappeared in each disc level (P > 0.05). Menopause is associated with lumbar disc degeneration. The association occurred in the first 15 YSM, suggesting estrogen deficiency might be a risk factor of disc degeneration of the lumbar spine. Further studies need to be carried out for deciding whether age or menopause plays a more important role in the progression of disc degeneration in the lumbar spine.
Protoporphyrin IX Content Correlates with Activity of Photobleaching Herbicides
Becerril, Jose M.; Duke, Stephen O.
1989-01-01
Several laboratories have demonstrated recently that photobleaching herbicides such as acifluorfen and oxadiazon cause accumulation of protoporphyrin IX (PPIX), a photodynamic pigment capable of herbicidal activity. We investigated, in acifluorfen-treated tissues, the in vivo stability of PPIX, the kinetics of accumulation, and the correlation between concentration of PPIX and herbicidal damage. During a 20 hour dark period, PPIX levels rose from barely detectable concentrations to 1 to 2 nanomoles per 50 cucumber (Cucumis sativus L.) cotyledon discs treated with 10 micromolar acifluorfen. When placed in 500 micromoles per square meter per second PAR, PPIX levels decayed logarithmically, with an initial half-life of about 2.5 hours. PPIX levels at each time after exposure to light correlated positively with the cellular damage that occurred during the following 1 hour in both green and yellow (tentoxin-treated) cucumber cotyledon tissues. PPIX levels in discs incubated for 20 hours in darkness correlated positively with the acifluorfen concentration in which they were incubated. In cucumber, the level of herbicidal damage caused by several p-nitrodiphenyl other herbicides, a p-chlorodiphenylether herbicide, and oxadiazon correlated positively with the amount of PPIX induced to accumulate by each of the herbicide treatments. Similar results were obtained with acifluorfen-treated pigweed and velvetleaf primary leaf tissues. In cucumber, PPIX levels increased within 15 and 30 minutes after exposure of discs to 10 micromolar acifluorfen in the dark and light, respectively. These data strengthen the view that PPIX is responsible for all or a major part of the photobleaching activity of acifluorfen and related herbicides. PMID:16666869
Xue, Yingen; Meats, Alan; Beattie, G Andrew C; Spooner-Hart, Robert; Herron, Grant A
2009-08-01
Occasional pesticide application in integrated pest management to at least part of a crop requires that any biological control agents must re-invade previously sprayed areas in order that resurgent pests can be constrained. The ability of the phytoseiid predatory mite Phytoseiulus persimilis to feed on adult two-spotted spider mite (TSSM) Tetranychus urticae on excised leaf discs in both control conditions and in a treatment with a sub lethal residue of agricultural mineral oil (AMO) was assessed. The predator exhibited a Type II functional response with the asymptote significantly higher in the AMO conditions due to the fact that the prey grew slower and reached a smaller size in this treatment. In terms of prey volume eaten, the satiation level of the predator was unchanged by the AMO deposits. The numbers of eggs produced by adult P. persimilis females at densities of 4, 8 and 16 TSSM adult females/disc in the control were significantly higher than those in the AMO treatment, but were similar for the higher density levels, 32 and 64 prey per disc. Thus the functional response in terms of volume of prey eaten explained the numerical response in terms of predator eggs produced. The presence of AMO deposits when the prey were at high density had no effect on predator efficiency (volume eaten) but resulted in a lower intake than that in control conditions when there was a greater distance between prey.
Weber, Kathryn T; Jacobsen, Timothy D; Maidhof, Robert; Virojanapa, Justin; Overby, Chris; Bloom, Ona; Quraishi, Shaheda; Levine, Mitchell; Chahine, Nadeen O
2015-03-01
Low back pain is a leading cause of disability worldwide and the second most common cause of physician visits. There are many causes of back pain, and among them, disc herniation and intervertebral disc degeneration are the most common diagnoses and targets for intervention. Currently, clinical treatment outcomes are not strongly correlated with diagnoses, emphasizing the importance for characterizing more completely the mechanisms of degeneration and their relationships with symptoms. This review covers recent studies elucidating cellular and molecular changes associated with disc mechanobiology, as it relates to degeneration and regeneration. Specifically, we review findings on the biochemical changes in disc diseases, including cytokines, chemokines, and proteases; advancements in disc disease diagnostics using imaging modalities; updates on studies examining the response of the intervertebral disc to injury; and recent developments in repair strategies, including cell-based repair, biomaterials, and tissue engineering. Findings on the effects of the omega-6 fatty acid, linoleic acid, on nucleus pulposus tissue engineering are presented. Studies described in this review provide greater insights into the pathogenesis of disc degeneration and may define new paradigms for early or differential diagnostics of degeneration using new techniques such as systemic biomarkers. In addition, research on the mechanobiology of disease enriches the development of therapeutics for disc repair, with potential to diminish pain and disability associated with disc degeneration.
Mountain Plains Learning Experience Guide: Automotive Repair. Course: Brake Systems.
ERIC Educational Resources Information Center
Schramm, C.; Osland, Walt
One of twelve individualized courses included in an automotive repair curriculum, this course covers theory, operation, and repair of drum brakes, disc brakes, and brake system components. The course is comprised of six units: (1) Fundamentals of Brake Systems, (2) Master Cylinder, (3) Drum Brakes, (4) Disc Brakes, (5) Power Brakes, and (6)…
NASA Astrophysics Data System (ADS)
Doǧan, S.; Nixon, C. J.; King, A. R.; Pringle, J. E.
2018-05-01
Accretion discs are generally warped. If a warp in a disc is too large, the disc can `break' apart into two or more distinct planes, with only tenuous connections between them. Further, if an initially planar disc is subject to a strong differential precession, then it can be torn apart into discrete annuli that precess effectively independently. In previous investigations, torque-balance formulae have been used to predict where and when the disc breaks into distinct parts. In this work, focusing on discs with Keplerian rotation and where the shearing motions driving the radial communication of the warp are damped locally by turbulence (the `diffusive' regime), we investigate the stability of warped discs to determine the precise criterion for an isolated warped disc to break. We find and solve the dispersion relation, which, in general, yields three roots. We provide a comprehensive analysis of this viscous-warp instability and the emergent growth rates and their dependence on disc parameters. The physics of the instability can be understood as a combination of (1) a term that would generally encapsulate the classical Lightman-Eardley instability in planar discs (given by ∂(νΣ)/∂Σ < 0) but is here modified by the warp to include ∂(ν1|ψ|)/∂|ψ| < 0, and (2) a similar condition acting on the diffusion of the warp amplitude given in simplified form by ∂(ν2|ψ|)/∂|ψ| < 0. We discuss our findings in the context of discs with an imposed precession, and comment on the implications for different astrophysical systems.
SITE program demonstration of the Rochem Disc Tube™ Module (DTM) developed by Rochem Separation systems Inc. The demonstration test was conducted at the central landfill Superfund site in Johnston, Rhode Island in August 1994. The DTM technology is an innovative membrane filtra...
Optic disc coloboma in two nigerian siblings: Case report and review of literature.
Babalola, Y O; Olawoye, O O; Idam, P O
2017-11-01
We report two cases of bilateral asymmetric optic disc coloboma (ODC) in siblings. The index patient is a 9-year-old Nigerian girl with severe cognitive deficit who presented with a poor vision of 3 years' duration. She had a history of childhood febrile convulsions and delayed developmental milestones. Her visual acuity could not be assessed because she had a cognitive deficit and expressive aphasia. Ocular examination revealed a very large excavated right optic disc with only a strip of remnant neuro-retinal rim superiorly, and a smaller left optic disc with inferior disc excavation, superior wedge of the pink neuro-retinal rim as well as a temporal optic disc pit. No systemic features of syndromes associated with ODCs and intellectual disability were present in both patients. The younger sibling an 8-year-old girl later presented to the eye clinic with a 5-month history of poor vision in the left eye. Ocular examination revealed visual acuity of 6/6 in the right eye and counting fingers in the left eye. Dilated binocular indirect ophthalmoscopy revealed a right large excavated colobomatous disc and a left small disc with infero-temporal disc coloboma.
NASA Technical Reports Server (NTRS)
Kempler, Steven; Teng, Bill; Friedl, Lawrence; Lynnes, Chris; Leptoukh, Gregory
2008-01-01
Recognizing the significance of NASA remote sensing Earth science data in monitoring and better understanding our planet s natural environment, NASA has implemented the Decision Support Through Earth Science Research Results program (NASA ROSES solicitations). a) This successful program has yielded several monitoring, surveillance, and decision support systems through collaborations with benefiting organizations. b) The Goddard Space Flight Center (GSFC) Earth Sciences Data and Information Services Center (GES DISC) has participated in this program on two projects (one complete, one ongoing), and has had opportune ad hoc collaborations gaining much experience in the formulation, management, development, and implementation of decision support systems utilizing NASA Earth science data. c) In addition, GES DISC s understanding of Earth science missions and resulting data and information, including data structures, data usability and interpretation, data interoperability, and information management systems, enables the GES DISC to identify challenges that come with bringing science data to decision makers. d) The purpose of this presentation is to share GES DISC decision support system project experiences in regards to system sustainability, required data quality (versus timeliness), data provider understanding of how decisions are made, and the data receivers willingness to use new types of information to make decisions, as well as other topics. In addition, defining metrics that really evaluate success will be exemplified.
The disappearance and reformation of the accretion disc during a low state of FO Aquarii
NASA Astrophysics Data System (ADS)
Hameury, J.-M.; Lasota, J.-P.
2017-09-01
Context. FO Aquarii, an asynchronous magnetic cataclysmic variable (intermediate polar) went into a low state in 2016, from which it slowly and steadily recovered without showing dwarf nova outbursts. This requires explanation since in a low state, the mass-transfer rate is in principle too low for the disc to be fully ionised and the disc should be subject to the standard thermal and viscous instability observed in dwarf novae. Aims: We investigate the conditions under which an accretion disc in an intermediate polar could exhibit a luminosity drop of two magnitudes in the optical band without showing outbursts. Methods: We use our numerical code for the time evolution of accretion discs, including other light sources from the system (primary, secondary, hot spot). Results: We show that although it is marginally possible for the accretion disc in the low state to stay on the hot stable branch, the required mass-transfer rate in the normal state would then have to be extremely high, of the order of 1019 g s-1 or even larger. This would make the system so intrinsically bright that its distance should be much larger than allowed by all estimates. We show that observations of FO Aqr are well accounted for by the same mechanism that we have suggested as explaining the absence of outbursts during low states of VY Scl stars: during the decay, the magnetospheric radius exceeds the circularisation radius, so that the disc disappears before it enters the instability strip for dwarf nova outbursts. Conclusions: Our results are unaffected, and even reinforced, if accretion proceeds both via the accretion disc and directly via the stream during some intermediate stages; the detailed process through which the disc disappears still requires investigation.
Intradiscal pressure study of percutaneous disc decompression with nucleoplasty in human cadavers.
Chen, Yung C; Lee, Sang-heon; Chen, Darwin
2003-04-01
Intradiscal pressure was measured after percutaneous disc decompression by nucleoplasty in human cadavers with different degrees of disc degeneration. To assess intradiscal pressure change after disc decompression, and to analyze the influence of degeneration on the intradiscal pressure change. Partial removal of the nucleus has been shown to decompress herniated discs, relieving pressure on nerve roots and, in some cases, offering relief from disc pain. Nucleoplasty, a new minimally invasive procedure using patented Coblation technology, combines coagulation and ablation for partial removal of the nucleus. Coblated channels remove the tissue volume and may decrease the disc pressure. Three fresh human cadaver spinal specimens (T8-L5; age, 54-84 years; mean age, 70.7 years) were used in this investigation. The intradiscal pressure was measured at three points: before treatment, after each channel was created, and after treatment using a 25-guage 6-inch needle connected to a Merit Medical Systems Intellisystem Inflation Monitor. The needles were calibrated initially to approximately 30 pounds per square inch. For the control, the change in disc pressure was recorded by the same procedure without using Coblation energy. To evaluate the effectiveness of nucleoplasty, disc pressure changes were compared between treatment with and without Coblation energy. Intradiscal pressure was markedly reduced in the younger, healthy disc cadaver. In the older, degenerative disc cadavers, the change in intradiscal pressure after nucleoplasty was very small. There was an inverse correlation between the degree of disc degeneration and the change in intradiscal pressure. Pressure reduction through nucleoplasty is highly dependent on the degree of spine degeneration. Nucleoplasty markedly reduced intradiscal pressure in nondegenerative discs, but had a negligible effect on highly degenerative discs.
1975-10-01
17’ 34V51 DISTANCE 11590.013 m SITE 9 DISC SITE 7 DISC SITE 9 DISC «; TTE 12 DISC 14937.421 m PAD ^,DOME ^ _"_’ - --^CONCRET t...air from either San Diego or Long Beach. To reach the station from the Operations Building at the Naval Undersea Center in Wilson Cove, drive...Operations Building at the Naval Undersea Center In Wilson Cove, drive southeast along the road for about one block. Cross the main road ,jnd proceed south
Kaminitz, Ayelet; Barzilay, Ran; Segal, Hadar; Taler, Michal; Offen, Daniel; Gil-Ad, Irit; Mechoulam, Raphael; Weizman, Abraham
2014-01-01
OBJECTIVES. Disrupted in schizophrenia 1 (DISC1) is considered the most prominent candidate gene for schizophrenia. In this study, we aimed to characterize behavioural and brain biochemical traits in a mouse expressing a dominant negative DISC1mutant (DN-DISC1). DN-DISC1 mice underwent behavioural tests to evaluate object recognition, social preference and social novelty seeking. ELISA was conducted on brain tissue to evaluate BDNF levels. Western blot was employed to measure BDNF receptor (TrkB) and cannabinoid receptor CB1. The mutant DISC1 mice displayed deficits in preference to social novelty while both social preference and object recognition were intact. Biochemical analysis of prefrontal cortex and hippocampus revealed a modest reduction in cortical TrkB protein levels of male mice while no differences in BDNF levels were observed. We found sex dependent differences in the expression of cannabinoid-1 receptors. We describe novel behavioural and biochemical abnormalities in the DN-DISC1 mouse model of schizophrenia. The data shows for the first time a possible link between DISC1 mutation and the cannabinoid system.
Birth of an Unusual Planetary System
NASA Technical Reports Server (NTRS)
2005-01-01
This artist's animation shows a brown dwarf surrounded by a swirling disc of planet-building dust. NASA's Spitzer Space Telescope spotted such a disc around a surprisingly low-mass brown dwarf, or 'failed star.' The brown dwarf, called OTS 44, is only 15 times the size of Jupiter, making it the smallest brown dwarf known to host a planet-forming, or protoplanetary disc. Astronomers believe that this unusual system will eventually spawn planets. If so, they speculate that OTS 44's disc has enough mass to make one small gas giant and a few Earth-sized rocky planets. OTS 44 is about 2 million years old. At this relatively young age, brown dwarfs are warm and appear reddish in color. With age, they grow cooler and darker.Vertebral degenerative disc disease severity evaluation using random forest classification
NASA Astrophysics Data System (ADS)
Munoz, Hector E.; Yao, Jianhua; Burns, Joseph E.; Pham, Yasuyuki; Stieger, James; Summers, Ronald M.
2014-03-01
Degenerative disc disease (DDD) develops in the spine as vertebral discs degenerate and osseous excrescences or outgrowths naturally form to restabilize unstable segments of the spine. These osseous excrescences, or osteophytes, may progress or stabilize in size as the spine reaches a new equilibrium point. We have previously created a CAD system that detects DDD. This paper presents a new system to determine the severity of DDD of individual vertebral levels. This will be useful to monitor the progress of developing DDD, as rapid growth may indicate that there is a greater stabilization problem that should be addressed. The existing DDD CAD system extracts the spine from CT images and segments the cortical shell of individual levels with a dual-surface model. The cortical shell is unwrapped, and is analyzed to detect the hyperdense regions of DDD. Three radiologists scored the severity of DDD of each disc space of 46 CT scans. Radiologists' scores and features generated from CAD detections were used to train a random forest classifier. The classifier then assessed the severity of DDD at each vertebral disc level. The agreement between the computer severity score and the average radiologist's score had a quadratic weighted Cohen's kappa of 0.64.
Scaling leaf measurements to estimate cotton canopy gas exchange
USDA-ARS?s Scientific Manuscript database
Diurnal leaf and canopy gas exchange of well watered field grown cotton were measured. Leaf measurements were made with a portable photosynthesis system and canopy measurements with open Canopy Evapo-Transpiration and Assimilation (CETA) systems. Leaf level measurements were arithmetically scaled to...
Be discs in coplanar circular binaries: Phase-locked variations of emission lines
NASA Astrophysics Data System (ADS)
Panoglou, Despina; Faes, Daniel M.; Carciofi, Alex C.; Okazaki, Atsuo T.; Baade, Dietrich; Rivinius, Thomas; Borges Fernandes, Marcelo
2018-01-01
In this paper, we present the first results of radiative transfer calculations on decretion discs of binary Be stars. A smoothed particle hydrodynamics code computes the structure of Be discs in coplanar circular binary systems for a range of orbital and disc parameters. The resulting disc configuration consists of two spiral arms, and this can be given as input into a Monte Carlo code, which calculates the radiative transfer along the line of sight for various observational coordinates. Making use of the property of steady disc structure in coplanar circular binaries, observables are computed as functions of the orbital phase. Some orbital-phase series of line profiles are given for selected parameter sets under various viewing angles, to allow comparison with observations. Flat-topped profiles with and without superimposed multiple structures are reproduced, showing, for example, that triple-peaked profiles do not have to be necessarily associated with warped discs and misaligned binaries. It is demonstrated that binary tidal effects give rise to phase-locked variability of the violet-to-red (V/R) ratio of hydrogen emission lines. The V/R ratio exhibits two maxima per cycle; in certain cases those maxima are equal, leading to a clear new V/R cycle every half orbital period. This study opens a way to identifying binaries and to constraining the parameters of binary systems that exhibit phase-locked variations induced by tidal interaction with a companion star.
NASA Technical Reports Server (NTRS)
Leptoukh, Gregory G.
2005-01-01
The NASA Goddard Earth Sciences Data and Information Services Center (GES DISC) is one of the major Distributed Active Archive Centers (DAACs) archiving and distributing remote sensing data from the NASA's Earth Observing System. In addition to providing just data, the GES DISC/DAAC has developed various value-adding processing services. A particularly useful service is data processing a t the DISC (i.e., close to the input data) with the users' algorithms. This can take a number of different forms: as a configuration-managed algorithm within the main processing stream; as a stand-alone program next to the on-line data storage; as build-it-yourself code within the Near-Archive Data Mining (NADM) system; or as an on-the-fly analysis with simple algorithms embedded into the web-based tools (to avoid downloading unnecessary all the data). The existing data management infrastructure at the GES DISC supports a wide spectrum of options: from data subsetting data spatially and/or by parameter to sophisticated on-line analysis tools, producing economies of scale and rapid time-to-deploy. Shifting processing and data management burden from users to the GES DISC, allows scientists to concentrate on science, while the GES DISC handles the data management and data processing at a lower cost. Several examples of successful partnerships with scientists in the area of data processing and mining are presented.
DUst around NEarby Stars. The survey observational results
NASA Astrophysics Data System (ADS)
Eiroa, C.; Marshall, J. P.; Mora, A.; Montesinos, B.; Absil, O.; Augereau, J. Ch.; Bayo, A.; Bryden, G.; Danchi, W.; del Burgo, C.; Ertel, S.; Fridlund, M.; Heras, A. M.; Krivov, A. V.; Launhardt, R.; Liseau, R.; Löhne, T.; Maldonado, J.; Pilbratt, G. L.; Roberge, A.; Rodmann, J.; Sanz-Forcada, J.; Solano, E.; Stapelfeldt, K.; Thébault, P.; Wolf, S.; Ardila, D.; Arévalo, M.; Beichmann, C.; Faramaz, V.; González-García, B. M.; Gutiérrez, R.; Lebreton, J.; Martínez-Arnáiz, R.; Meeus, G.; Montes, D.; Olofsson, G.; Su, K. Y. L.; White, G. J.; Barrado, D.; Fukagawa, M.; Grün, E.; Kamp, I.; Lorente, R.; Morbidelli, A.; Müller, S.; Mutschke, H.; Nakagawa, T.; Ribas, I.; Walker, H.
2013-07-01
Context. Debris discs are a consequence of the planet formation process and constitute the fingerprints of planetesimal systems. Their solar system counterparts are the asteroid and Edgeworth-Kuiper belts. Aims: The DUNES survey aims at detecting extra-solar analogues to the Edgeworth-Kuiper belt around solar-type stars, putting in this way the solar system into context. The survey allows us to address some questions related to the prevalence and properties of planetesimal systems. Methods: We used Herschel/PACS to observe a sample of nearby FGK stars. Data at 100 and 160 μm were obtained, complemented in some cases with observations at 70 μm, and at 250, 350 and 500 μm using SPIRE. The observing strategy was to integrate as deep as possible at 100 μm to detect the stellar photosphere. Results: Debris discs have been detected at a fractional luminosity level down to several times that of the Edgeworth-Kuiper belt. The incidence rate of discs around the DUNES stars is increased from a rate of ~12.1% ± 5% before Herschel to ~20.2% ± 2%. A significant fraction (~52%) of the discs are resolved, which represents an enormous step ahead from the previously known resolved discs. Some stars are associated with faint far-IR excesses attributed to a new class of cold discs. Although it cannot be excluded that these excesses are produced by coincidental alignment of background galaxies, statistical arguments suggest that at least some of them are true debris discs. Some discs display peculiar SEDs with spectral indexes in the 70-160 μm range steeper than the Rayleigh-Jeans one. An analysis of the debris disc parameters suggests that a decrease might exist of the mean black body radius from the F-type to the K-type stars. In addition, a weak trend is suggested for a correlation of disc sizes and an anticorrelation of disc temperatures with the stellar age. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.Appendices are available in electronic form at http://www.aanda.orgTables 14 and 15 are also available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/555/A11Full Tables 2-5, 10 and 12 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/555/A11
NASA Astrophysics Data System (ADS)
Restrepo, Simon; Basler, Konrad
2016-08-01
Calcium signalling is a highly versatile cellular communication system that modulates basic functions such as cell contractility, essential steps of animal development such as fertilization and higher-order processes such as memory. We probed the function of calcium signalling in Drosophila wing imaginal discs through a combination of ex vivo and in vivo imaging and genetic analysis. Here we discover that wing discs display slow, long-range intercellular calcium waves (ICWs) when mechanically stressed in vivo or cultured ex vivo. These slow imaginal disc intercellular calcium waves (SIDICs) are mediated by the inositol-3-phosphate receptor, the endoplasmic reticulum (ER) calcium pump SERCA and the key gap junction component Inx2. The knockdown of genes required for SIDIC formation and propagation negatively affects wing disc recovery after mechanical injury. Our results reveal a role for ICWs in wing disc homoeostasis and highlight the utility of the wing disc as a model for calcium signalling studies.
Burtis, C.A.; Johnson, W.F.; Walker, W.A.
1985-08-05
A rotor and disc assembly for use in a centrifugal fast analyzer. The assembly is designed to process multiple samples of whole blood followed by aliquoting of the resultant serum into precisely measured samples for subsequent chemical analysis. The assembly requires minimal operator involvement with no mechanical pipetting. The system comprises: (1) a whole blood sample disc; (2) a serum sample disc; (3) a sample preparation rotor; and (4) an analytical rotor. The blood sample disc and serum sample disc are designed with a plurality of precision bore capillary tubes arranged in a spoked array. Samples of blood are loaded into the blood sample disc by capillary action and centrifugally discharged into cavities of the sample preparation rotor where separation of serum and solids is accomplished. The serum is loaded into the capillaries of the serum sample disc by capillary action and subsequently centrifugally expelled into cuvettes of the analyticaly rotor for conventional methods. 5 figs.
Burtis, Carl A.; Johnson, Wayne F.; Walker, William A.
1988-01-01
A rotor and disc assembly for use in a centrifugal fast analyzer. The assembly is designed to process multiple samples of whole blood followed by aliquoting of the resultant serum into precisely measured samples for subsequent chemical analysis. The assembly requires minimal operator involvement with no mechanical pipetting. The system comprises (1) a whole blood sample disc, (2) a serum sample disc, (3) a sample preparation rotor, and (4) an analytical rotor. The blood sample disc and serum sample disc are designed with a plurality of precision bore capillary tubes arranged in a spoked array. Samples of blood are loaded into the blood sample disc in capillary tubes filled by capillary action and centrifugally discharged into cavities of the sample preparation rotor where separation of serum and solids is accomplished. The serum is loaded into the capillaries of the serum sample disc by capillary action and subsequently centrifugally expelled into cuvettes of the analytical rotor for analysis by conventional methods.
Rethinking Black Hole Accretion Discs
NASA Astrophysics Data System (ADS)
Salvesen, Greg
Accretion discs are staples of astrophysics. Tapping into the gravitational potential energy of the accreting material, these discs are highly efficient machines that produce copious radiation and extreme outflows. While interesting in their own right, accretion discs also act as tools to study black holes and directly influence the properties of the Universe. Black hole X-ray binaries are fantastic natural laboratories for studying accretion disc physics and black hole phenomena. Among many of the curious behaviors exhibited by these systems are black hole state transitions -- complicated cycles of dramatic brightening and dimming. Using X-ray observations with high temporal cadence, we show that the evolution of the accretion disc spectrum during black hole state transitions can be described by a variable disc atmospheric structure without invoking a radially truncated disc geometry. The accretion disc spectrum can be a powerful diagnostic for measuring black hole spin if the effects of the disc atmosphere on the emergent spectrum are well-understood; however, properties of the disc atmosphere are largely unconstrained. Using statistical methods, we decompose this black hole spin measurement technique and show that modest uncertainties regarding the disc atmosphere can lead to erroneous spin measurements. The vertical structure of the disc is difficult to constrain due to our ignorance of the contribution to hydrostatic balance by magnetic fields, which are fundamental to the accretion process. Observations of black hole X-ray binaries and the accretion environments near supermassive black holes provide mounting evidence for strong magnetization. Performing numerical simulations of accretion discs in the shearing box approximation, we impose a net vertical magnetic flux that allows us to effectively control the level of disc magnetization. We study how dynamo activity and the properties of turbulence driven by the magnetorotational instability depend on the magnetized state of the gas, spanning weak-to-strong disc magnetization regimes. We also demonstrate that a background poloidal magnetic flux is required to form and sustain a strongly magnetized accretion disc. This thesis motivates the need for understanding how magnetic fields affect the observed spectrum from black hole accretion discs.
A disc inside the bipolar planetary nebula M2-9
NASA Astrophysics Data System (ADS)
Lykou, F.; Chesneau, O.; Zijlstra, A. A.; Castro-Carrizo, A.; Lagadec, E.; Balick, B.; Smith, N.
2011-03-01
Aims: Bipolarity in proto-planetary and planetary nebulae is associated with events occurring in or around their cores. Past infrared observations have revealed the presence of dusty structures around the cores, many in the form of discs. Characterising those dusty discs provides invaluable constraints on the physical processes that govern the final mass expulsion of intermediate mass stars. We focus this study on the famous M2-9 bipolar nebula, where the moving lighthouse beam pattern indicates the presence of a wide binary. The compact and dense dusty core in the centre of the nebula can be studied by means of optical interferometry. Methods: M2-9 was observed with VLTI/MIDI at 39-47 m baselines with the UT2-UT3 and UT3-UT4 baseline configurations. These observations are interpreted using a dust radiative transfer Monte Carlo code. Results: A disc-like structure is detected perpendicular to the lobes, and a good fit is found with a stratified disc model composed of amorphous silicates. The disc is compact, 25 × 35 mas at 8 μm and 37 × 46 mas at 13 μm. For the adopted distance of 1.2 kpc, the inner rim of the disc is ~15 AU. The mass represents a few percent of the mass found in the lobes. The compactness of the disc puts strong constraints on the binary content of the system, given an estimated orbital period 90-120 yr. We derive masses of the binary components between 0.6-1.0 M⊙ for a white dwarf and 0.6-1.4 M⊙ for an evolved star. We present different scenarios on the geometric structure of the disc accounting for the interactions of the binary system, which includes an accretion disc as well. Based on observations collected at the European Organisation for Astronomical Research in the Southern Hemisphere, Chile, ESO N: 079.D-146.
Bacterial Outer Membrane Vesicles Induce Plant Immune Responses.
Bahar, Ofir; Mordukhovich, Gideon; Luu, Dee Dee; Schwessinger, Benjamin; Daudi, Arsalan; Jehle, Anna Kristina; Felix, Georg; Ronald, Pamela C
2016-05-01
Gram-negative bacteria continuously pinch off portions of their outer membrane, releasing membrane vesicles. These outer membrane vesicles (OMVs) are involved in multiple processes including cell-to-cell communication, biofilm formation, stress tolerance, horizontal gene transfer, and virulence. OMVs are also known modulators of the mammalian immune response. Despite the well-documented role of OMVs in mammalian-bacterial communication, their interaction with plants is not well studied. To examine whether OMVs of plant pathogens modulate the plant immune response, we purified OMVs from four different plant pathogens and used them to treat Arabidopsis thaliana. OMVs rapidly induced a reactive oxygen species burst, medium alkalinization, and defense gene expression in A. thaliana leaf discs, cell cultures, and seedlings, respectively. Western blot analysis revealed that EF-Tu is present in OMVs and that it serves as an elicitor of the plant immune response in this form. Our results further show that the immune coreceptors BAK1 and SOBIR1 mediate OMV perception and response. Taken together, our results demonstrate that plants can detect and respond to OMV-associated molecules by activation of their immune system, revealing a new facet of plant-bacterial interactions.
Hydrodynamic outcomes of planet scattering in transitional discs
NASA Astrophysics Data System (ADS)
Moeckel, Nickolas; Armitage, Philip J.
2012-01-01
A significant fraction of unstable multiple planet systems are likely to scatter during the transitional disc phase as gas damping becomes ineffectual. Using a large ensemble of FARGO hydrodynamic simulations and MERCURY N-body integrations, we directly follow the dynamics of planet-disc and planet-planet interactions through the clearing phase and through 50 Myr of planetary system evolution. Disc clearing is assumed to occur as a result of X-ray-driven photoevaporation. We find that the hydrodynamic evolution of individual scattering systems is complex, and can involve phases in which massive planets orbit within eccentric gaps, or accrete directly from the disc without a gap. Comparing the results to a reference gas-free model, we find that the N-body dynamics and hydrodynamics of scattering into one- and two-planet final states are almost identical. The eccentricity distributions in these channels are almost unaltered by the presence of gas. The hydrodynamic simulations, however, also form a population of low-eccentricity three-planet systems in long-term stable configurations, which are not found in N-body runs. The admixture of these systems results in modestly lower eccentricities in hydrodynamic as opposed to gas-free simulations. The precise incidence of these three-planet systems is likely a function of the initial conditions; different planet set-ups (number or spacing) may change the quantitative character of this result. We analyse the properties of surviving multiple planet systems, and show that only a small fraction (a few per cent) enter mean motion resonances after scattering, while a larger fraction form stable resonant chains and avoid scattering entirely. Our results remain consistent with the hypothesis that exoplanet eccentricity results from scattering, though the detailed agreement between observations and gas-free simulation results is likely coincidental. We discuss the prospects for further tests of scattering models by observing planets or non-axisymmetric gas structure in transitional discs.
Mueller, Andrea; Fujioka-Kobayashi, Masako; Mueller, Heinz-Dieter; Lussi, Adrian; Sculean, Anton; Schmidlin, Patrick R; Miron, Richard J
2017-05-01
Hyaluronic acid (HA) is a natural constituent of connective tissues and plays an important role in their development, maintenance, and regeneration. Recently, HA has been shown to improve wound healing. However, no basic in vitro study to date has investigated its mode of action. Therefore, the purpose of this study was to examine morphological changes of dentin surfaces following HA coating and thereafter investigate the influence of periodontal ligament (PDL) cell survival, attachment, and spreading to dentin discs. HA was coated onto dentin discs utilizing either non-cross-linked (HA) or cross-linked (HA cl) delivery systems. Morphological changes to dentin discs were then assessed using scanning electron microscopy (SEM). Thereafter, human PDL cells were seeded under three in vitro conditions including (1) dilution of HA (1:100), (2) dilution of HA (1:10), and (3) HA coated directly to dentin discs. Samples were then investigated for PDL cell survival, attachment, and spreading using a live/dead assay, cell adhesion assay, and SEM imaging, respectively. While control dentin discs demonstrated smooth surfaces both at low and high magnification, the coating of HA altered surface texture of dentin discs by increasing surface roughness. HA cl further revealed greater surface texture/roughness likely due to the cross-linking carrier system. Thereafter, PDL cells were seeded on control and HA coated dentin discs and demonstrated a near 100 % survival rate for all samples demonstrating high biocompatibility of HA at dilutions of both 1:100 and 1:10. Interestingly, non-cross-linked HA significantly increased cell numbers at 8 h, whereas cross-linked HA improved cell spreading as qualitatively assessed by SEM. The results from the present study demonstrate that both carrier systems for HA were extremely biocompatible and demonstrated either improved cell numbers or cell spreading onto dentin discs. Future in vitro and animal research is necessary to further characterize the optimal delivery system of HA for improved clinical use. HA is a highly biocompatible material that may improve PDL cell attachment or spreading on dentin.
NASA Astrophysics Data System (ADS)
Zhao, Bo; Caselli, Paola; Li, Zhi-Yun; Krasnopolsky, Ruben
2018-02-01
Efficient magnetic braking is a formidable obstacle to the formation of rotationally supported discs (RSDs) around protostars in magnetized dense cores. We have previously shown, through 2D (axisymmetric) non-ideal magnetohydrodynamic simulations, that removing very small grains (VSGs: ∼10 Å to few 100 Å) can greatly enhance ambipolar diffusion and enable the formation of RSDs. Here, we extend the simulations of disc formation enabled by VSG removal to 3D. We find that the key to this scenario of disc formation is that the drift velocity of the magnetic field almost cancels out the infall velocity of the neutrals in the 102-103 au scale 'pseudo-disc' where the field lines are most severely pinched and most of protostellar envelope mass infall occurs. As a result, the bulk neutral envelope matter can collapse without dragging much magnetic flux into the disc-forming region, which lowers the magnetic braking efficiency. We find that the initial discs enabled by VSG removal tend to be Toomre-unstable, which leads to the formation of prominent spiral structures that function as centrifugal barriers. The piling-up of infall material near the centrifugal barrier often produces dense fragments of tens of Jupiter masses, especially in cores that are not too strongly magnetized. Some fragments accrete on to the central stellar object, producing bursts in mass accretion rate. Others are longer lived, although whether they can survive for a long term to produce multiple systems remains to be ascertained. Our results highlight the importance of dust grain evolution in determining the formation and properties of protostellar discs and potentially multiple systems.
Changes in orientation and shape of protoplanetary discs moving through an ambient medium
NASA Astrophysics Data System (ADS)
Wijnen, T. P. G.; Pelupessy, F. I.; Pols, O. R.; Portegies Zwart, S.
2017-08-01
Misalignments between the orbital planes of planets and the equatorial planes of their host stars have been observed in our solar system, in transiting exoplanets, and for the orbital planes of debris discs. We present a mechanism that causes such a spin-orbit misalignment for a protoplanetary disc due to its movement through an ambient medium. Our physical explanation of the mechanism is based on the theoretical solutions to the Stark problem. We test this idea by performing self-consistent hydrodynamical simulations and simplified gravitational N-body simulations. The N-body model reduces the mechanism to the relevant physical processes. The hydrodynamical simulations show the mechanism in its full extent, including gas-dynamical and viscous processes in the disc which are not included in the theoretical framework. We find that a protoplanetary disc embedded in a flow changes its orientation as its angular momentum vector tends to align parallel to the relative velocity vector. Due to the force exerted by the flow, orbits in the disc become eccentric, which produces a net torque and consequentially changes the orbital inclination. The tilting of the disc causes it to contract. Apart from becoming lopsided, the gaseous disc also forms a spiral arm even if the inclination does not change substantially. The process is most effective at high velocities and observational signatures are therefore mostly expected in massive star-forming regions and around winds or supernova ejecta. Our N-body model indicates that the interaction with supernova ejecta is a viable explanation for the observed spin-orbit misalignment in our solar system.
NASA Astrophysics Data System (ADS)
Forgan, D. H.; Hall, C.; Meru, F.; Rice, W. K. M.
2018-03-01
It is likely that most protostellar systems undergo a brief phase where the protostellar disc is self-gravitating. If these discs are prone to fragmentation, then they are able to rapidly form objects that are initially of several Jupiter masses and larger. The fate of these disc fragments (and the fate of planetary bodies formed afterwards via core accretion) depends sensitively not only on the fragment's interaction with the disc, but also with its neighbouring fragments. We return to and revise our population synthesis model of self-gravitating disc fragmentation and tidal downsizing. Amongst other improvements, the model now directly incorporates fragment-fragment interactions while the disc is still present. We find that fragment-fragment scattering dominates the orbital evolution, even when we enforce rapid migration and inefficient gap formation. Compared to our previous model, we see a small increase in the number of terrestrial-type objects being formed, although their survival under tidal evolution is at best unclear. We also see evidence for disrupted fragments with evolved grain populations - this is circumstantial evidence for the formation of planetesimal belts, a phenomenon not seen in runs where fragment-fragment interactions are ignored. In spite of intense dynamical evolution, our population is dominated by massive giant planets and brown dwarfs at large semimajor axis, which direct imaging surveys should, but only rarely, detect. Finally, disc fragmentation is shown to be an efficient manufacturer of free-floating planetary mass objects, and the typical multiplicity of systems formed via gravitational instability will be low.
Mertz, Stuart M.; Arntzen, Charles J.
1977-01-01
Pathotoxin preparations were obtained from either axenic culture filtrate of race T of Bipolaris maydis (Nisikado) Shoemaker (new culture media and toxin purification procedures are described) or extracts of maize leaves infected with the fungus. The toxins (10−6 to 10−8m) caused inhibition of [86Rb]K+ uptake in leaf discs and apical root segments of Zea mays L. cv W64A Texas (Tcms) and normal (N) cytoplasms. Significant inhibition was measurable as early as 5 min after adding toxin. In Tcms per cent inhibition was increased by increasing toxin concentration and time in toxin, by using solution at pH 5 rather than pH 7, by decreasing external KCl concentration over the range 50 to 0.1 mm (in the presence of 0.5 mm CaSO4), or by exposing leaf discs to light rather than dark during the uptake period in toxin. Root uptake of 22Na+ and 36Cl− was inhibited to a lesser extent than K+. Inhibition of 32PO43− uptake occurred after 40 min when cyclosis had ceased. When combined with data in the literature, our data indicate that the plasmalemma is the probable primary site of toxin action in N and Tcms maize. Comparison of the effects of toxin on K+ uptake in N and Tcms maize suggests the existence of more than one mode of toxin action: a weak disruptive effect in N and Tcms, and in addition, specific membrane sites in Tcms involved in monovalent ion uptake. Six genotypes in N or Tcms cytoplasm which exhibited different degrees of disease susceptibility in the field showed a corresponding gradation of susceptibility to the toxin when a K+ uptake bioassay was used. This correlation is strong evidence that the sites of toxin action affecting K+ transport have characteristics closely related to cellular factors regulating susceptibility to fungal attack. PMID:16660094
Müller, Caroline; van Loon, Joop; Ruschioni, Sara; De Nicola, Gina Rosalinda; Olsen, Carl Erik; Iori, Renato; Agerbirk, Niels
2015-10-01
Isothiocyanates (ITCs), released from Brassicales plants after hydrolysis of glucosinolates, are known for their negative effects on herbivores but mechanisms have been elusive. The ITCs are initially present in dissolved form at the site of herbivore feeding, but volatile ITCs may subsequently enter the gas phase and all ITCs may react with matrix components. Deterrence to herbivores resulting from topically applied volatile ITCs in artificial feeding assays may hence lead to ambiguous conclusions. In the present study, the non-volatile ITC moringin (4-(α-L-rhamnopyranosyloxy)benzyl ITC) and its glucosinolate precursor glucomoringin were examined for effects on behaviour and taste physiology of specialist insect herbivores of Brassicales. In feeding bioassays, glucomoringin was not deterrent to larvae of Pieris napi (Lepidoptera: Pieridae) and Athalia rosae (Hymenoptera: Tenthredinidae), which are adapted to glucosinolates. Glucomoringin stimulated feeding of larvae of the related Pieris brassicae (Lepidoptera: Pieridae) and also elicited electrophysiological activity from a glucosinolate-sensitive gustatory neuron in the lateral maxillary taste sensilla. In contrast, the ITC moringin was deterrent to P. napi and P. brassicae at high levels and to A. rosae at both high and low levels when topically applied to cabbage leaf discs (either 12, 120 or 1200 nmol moringin per leaf disc of 1cm diameter). Survival of A. rosae was also significantly reduced when larvae were kept on leaves treated with moringin for several days. Furthermore, moringin elicited electrophysiological activity in a deterrent-sensitive neuron in the medial maxillary taste sensillum of P. brassicae, providing a sensory mechanism for the deterrence and the first known ITC taste response of an insect. In simulated feeding assays, recovery of moringin was high, in accordance with its non-volatile nature. Our results demonstrate taste-mediated deterrence of a non-volatile, natural ITC to glucosinolate-adapted insects. Copyright © 2015 Elsevier Ltd. All rights reserved.
Brévault, T; Carletto, J; Tribot, J; Vanlerberghe-Masutti, F
2011-08-01
Field populations of the cotton aphid, Aphis gossypii Glover, are structured into geographically widespread host races. In the cotton-producing regions of West and Central Africa (WCA), two genotypes have been repeatedly detected within the cotton host race, one of which (Burk1) is prevalent (>90%) and resistant to several insecticides, as opposed to the second one (Ivo). Here, we conducted whole plant and field cage experiments to test hypotheses for such low genetic diversity, including selection from insecticide treatments, interclonal competition and adaptation to host plant, or climatic conditions. To assess the genetic diversity of immigrant aphids, alatae were trapped and collected on cotton and relay host plants (okra and roselle) in the early cropping season. Individuals were genotyped at eight specific microsatellite loci and characterized by a multilocus genotype (MLG). When independently transferred from cotton (Gossypium hirustum L.) leaf discs to whole plants (G. hirsutum and G. arboreum, roselle and okra), Ivo and Burk1 performed equally well. When concurrently transferred from cotton leaf discs to the same plant species, Ivo performed better than Burk1, indicating that competition favoured Ivo. This was also the case on G. hirsutum growing outdoors. Conversely, Burk1 prevailed when cotton plants were sprayed with insecticides. In experiments where aphids were allowed to move to neighbouring plants, Burk1 was better represented than Ivo on low-populated plants, suggesting that dispersal may be a way to avoid competition on crowded plants. Most cotton aphids collected on cotton or relay host plants in the early cropping season were Burk1 (>90%), indicating high dispersal ability and, probably reflecting high frequency on host plants from which they dispersed. In the agricultural landscape of WCA, the use of broad-range insecticides on both cotton and relay host plants has led to the prevalence of one genotype of A. gossypii resistant to different classes of insecticides. Deployment of widespread and integrated pest management strategies are needed to restore cotton aphid control.
Changes in intervertebral disc cross-sectional area with bed rest and space flight
NASA Technical Reports Server (NTRS)
LeBlanc, A. D.; Evans, H. J.; Schneider, V. S.; Wendt, R. E. 3rd; Hedrick, T. D.
1994-01-01
STUDY DESIGN. We measured the cross-sectional area of the intervertebral discs of normal volunteers after an overnight rest; before, during, and after 5 or 17 weeks of bed rest; and before and after 8 days of weightlessness. OBJECTIVES. This study sought to determine the degree of expansion of the lumbar discs resulting from bed rest and space flight. SUMMARY OF BACKGROUND DATA. Weightlessness and bed rest, an analog for weightlessness, reduce the mechanical loading on the musculoskeletal system. When unloaded, intervertebral discs will expand, increasing the nutritional diffusion distance and altering the mechanical properties of the spine. METHODS. Magnetic resonance imaging was used to measure the cross-sectional area and transverse relaxation time (T2) of the intervertebral discs. RESULTS. Overnight or longer bed rest causes expansion of the disc area, which reaches an equilibrium value of about 22% (range 10-40%) above baseline within 4 days. Increases in disc area were associated with modest increases in disc T2. During bed rest, disc height increased approximately 1 mm, about one-half of previous estimates based on body height measurements. After 5 weeks of bed rest, disc area returned to baseline within a few days of ambulation, whereas after 17 weeks, disc area remained above baseline 6 weeks after reambulation. After 8 days of weightlessness, T2, disc area, and lumbar length were not significantly different from baseline values 24 hours after landing. CONCLUSIONS. Significant adaptive changes in the intervertebral discs can be expected during weightlessness. These changes, which are rapidly reversible after short-duration flights, may be an important factor during and after long-duration missions.
NASA Astrophysics Data System (ADS)
Vidal Vázquez, E.; Miranda, J. G. V.; Mirás-Avalos, J. M.; Díaz, M. C.; Paz-Ferreiro, J.
2009-04-01
Mathematical description of the spatial characteristics of soil surface microrelief still remains a challenge. Soil surface roughness parameters are required for modelling overland flow and erosion. The objective of this work was to evaluate the potential of multifractal for analyzing the decay of initial surface roughness induced by natural rainfall under different soil tillage systems. Field experiments were performed on an Oxisol at Campinas, São Paulo State (Brazil). Six tillage treatments, namely, disc harrow, disc plow, chisel plow, disc harrow + disc level, disc plow + disc level and chisel plow + disc level were tested. In each plot soil surface microrelief was measured for times, with increasing amounts of natural rainfall using a pinmeter. The sampling scheme was a square grid with 25 x 25 mm point spacing and the plot size was 1350 x 1350 mm, so that each data set consisted of 3025 individual elevation points. Duplicated measurements were taken per treatment and date, yielding a total of 48 experimental data sets. All the investigated microrelief data sets exhibited, in general, scale properties, and the degree of multifractality showed wide differences between them. Multifractal analysis distinguishes two different patterns of soil surface microrelief, the first one has features close to monofractal spectra and the second clearly indicates multifractal behavior. Both, singularity spectra and generalized dimension spectra allow differentiating between soil tillage systems. In general, changes in values of multifractal parameters under simulated rainfall showed no or little correspondence with the evolution of the vertical microrelief component described by indices such as the standard deviation of the point height measurements. Multifractal parameters provided valuable information for chararacterizing the spatial features of soil surface microrelief as they were able to discriminate data sets with similar values for the vertical component of roughness.
Influence of chilling and drought on water relations and abscisic acid accumulation in bean
DOE Office of Scientific and Technical Information (OSTI.GOV)
Vernieri, P.; Pardossi, A.; Tognoni, F.
Intact bean seedlings were subjected to either chilling (4{degree}C) or drought stress. Leaf water relations and abscisic acid (ABA) content were monitored throughout a stress-recovery cycle. Chilling at low relative humidity (RH) and drought caused similar water deficits, as indicated by the decline in relative water content and water potentials, but they had different effects on ABA accumulation. There was a rapid increase in ABA levels in the leaves of water-deprived plants while only slight ABA accumulation was observed after 48 h of chilling (4{degree}C). After 24 h cold treatment there were large changes in turgor but no change inmore » ABA content. Plants chilled for 24 h accumulated ABA only when transferred to recovery conditions (20{degree}C, 90-95% RH, in the dark) to an extent that was related to the rate of leaf rehydration. When the chilling treatment was performed in a water-saturated atmosphere, plants did not suffer any water stress and ABA levels did not increase over a period of 48 h. However, when the chilling treatment lasted for a longer period (72 h), a significant increase in ABA levels was found also in the absence of water deficit. Experiments performed with leaf discs incubated in a mannitol solution (osmotic potential {minus}1{center dot}6 MPa) at different temperatures indicated that low temperature markedly inhibits ABA synthesis and that water stress induces increases in ABA content only at non-limiting warm temperatures.« less
[Induction and in vitro culture of hairy roots of Dianthus caryophyllus and its plant regeneration].
Shi, Heping; Zhu, Yuanfeng; Wang, Bei; Sun, Jiangbing; Huang, Shengqin
2014-11-01
To use Agrobacterium rhizogenes-induced hairy roots to create new germplasm of Dianthus caryophyllus, we transformed D. caryophyllus with A. rhizogenes by leaf disc for plant regeneration from hairy roots. The white hairy roots could be induced from the basal surface of leaf explants of D. caryophyllus 12 days after inoculation with A. rhizogenes ATCC15834. The percentage of the rooting leaf explants was about 90% 21 days after inoculation. The hairy roots could grow rapidly and autonomously in liquid or solid phytohormone-free MS medium. The transformation was confirmed by PCR amplification of rol gene of Ri plasmid and silica gel thin-layer chromatography of opines from D. caryophyllus hairy roots. Hairy roots could form light green callus after cultured on MS+6-BA 1.0-3.0 mg/L + NAA 0.1-0.2 mg/L for 15 days. The optimum medium for adventitious shoots formation was MS + 6-BA 2.0 mg/L + NAA 0.02 mg/L, where the rate of adventitious shoot induction was 100% after cultured for 6 weeks. The mean number of adventitious shoot per callus was 30-40. The adventitious shoots can form roots when cultured on phytohormone-free 1/2 MS or 1/2 MS +0.5 mg/L NAA for 10 days. When the rooted plantlets transplanted in the substrate mixed with perlite sand and peat (volume ratio of 1:2), the survival rate was above 95%.
Antioxidant, antimicrobial and toxicological properties of Schinus molle L. essential oils.
Martins, Maria do Rosário; Arantes, Silvia; Candeias, Fátima; Tinoco, Maria Teresa; Cruz-Morais, Júlio
2014-01-01
Schinus molle L. has been used in folk medicine as antibacterial, antiviral, topical antiseptic, antifungal, antioxidant, anti-inflammatory, anti-tumoural as well as antispasmodic and analgesic; however, there are few studies of pharmacological and toxicological properties of Schinus molle essential oils. The aim of this study was to evaluate the antioxidant and antimicrobial activities of Schinus molle leaf and fruit essential oils, correlated with their chemical composition and evaluate their acute toxicity. The chemical composition of Schinus molle leaf and fruit essential oils were evaluated by GC-FID and GC-MS. Antioxidant properties were determined using the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) free radical and β-carotene/linoleic acid methods. Antimicrobial properties were evaluated by the agar disc diffusion method and minimal inhibitory concentration assay. Toxicity in Artemia salina and acute toxicity with behavioural screening in mice were evaluated. The dominant compounds found in leaf and fruit essential oils (EOs) were monoterpene hydrocarbons, namely α-phellandrene, β-phellandrene, β-myrcene, limonene and α-pinene. EOs showed low scavenging antioxidant activity by the DPPH free radical method and a higher activity by the β-carotene/linoleic acid method. Antimicrobial activity of EOs was observed for Gram+, Gram- pathogenic bacteria and food spoilage fungi. EOs showed totoxicity for Artemia salina and lower toxicity in Swiss mice. The result showed that EOs of leaves and fruits of Schinus molle demonstrated antioxidant and antimicrobial properties, suggesting their potential use in food or pharmaceutical industries. © 2013 Published by Elsevier Ireland Ltd.
Mishra, Amita; Sharma, Amit Kumar; Kumar, Shashank; Saxena, Ajit K.; Pandey, Abhay K.
2013-01-01
The present study reports the phytochemical profiling, antimicrobial, antioxidant, and anticancer activities of Bauhinia variegata leaf extracts. The reducing sugar, anthraquinone, and saponins were observed in polar extracts, while terpenoids and alkaloids were present in nonpolar and ethanol extracts. Total flavonoid contents in various extracts were found in the range of 11–222.67 mg QE/g. In disc diffusion assays, petroleum ether and chloroform fractions exhibited considerable inhibition against Klebsiella pneumoniae. Several other extracts also showed antibacterial activity against pathogenic strains of E. coli, Proteus spp. and Pseudomonas spp. Minimum bactericidal concentration (MBC) values of potential extracts were found between 3.5 and 28.40 mg/mL. The lowest MBC (3.5 mg/mL) was recorded for ethanol extract against Pseudomonas spp. The antioxidant activity of the extracts was compared with standard antioxidants. Dose dependent response was observed in reducing power of extracts. Polar extracts demonstrated appreciable metal ion chelating activity at lower concentrations (10–40 μg/mL). Many extracts showed significant antioxidant response in beta carotene bleaching assay. AQ fraction of B. variegata showed pronounced cytotoxic effect against DU-145, HOP-62, IGR-OV-1, MCF-7, and THP-1 human cancer cell lines with 90–99% cell growth inhibitory activity. Ethyl acetate fraction also produced considerable cytotoxicity against MCF-7 and THP-1 cell lines. The study demonstrates notable antibacterial, antioxidant, and anticancer activities in B. variegata leaf extracts. PMID:24093108
First results of the SONS survey: submillimetre detections of debris discs
NASA Astrophysics Data System (ADS)
Panić, O.; Holland, W. S.; Wyatt, M. C.; Kennedy, G. M.; Matthews, B. C.; Lestrade, J. F.; Sibthorpe, B.; Greaves, J. S.; Marshall, J. P.; Phillips, N. M.; Tottle, J.
2013-10-01
New detections of debris discs at submillimetre wavelengths present highly valuable complementary information to prior observations of these sources at shorter wavelengths. Characterization of discs through spectral energy distribution modelling including the submillimetre fluxes is essential for our basic understanding of disc mass and temperature, and presents a starting point for further studies using millimetre interferometric observations. In the framework of the ongoing SCUBA-2 Observations of Nearby Stars, the instrument SCUBA-2 on the James Clerk Maxwell Telescope was used to provide measurements of 450 and 850 μm fluxes towards a large sample of nearby main-sequence stars with debris discs detected previously at shorter wavelengths. We present the first results from the ongoing survey, concerning 850 μm detections and 450 μm upper limits towards 10 stars, the majority of which are detected at submillimetre wavelengths for the first time. One, or possibly two, of these new detections is likely a background source. We fit the spectral energy distributions of the star+disc systems with a blackbody emission approach and derive characteristic disc temperatures. We use these temperatures to convert the observed fluxes to disc masses. We obtain a range of disc masses from 0.001 to 0.1 M⊕, values similar to the prior dust mass measurements towards debris discs. There is no evidence for evolution in dust mass with age on the main sequence, and indeed the upper envelope remains relatively flat at ≈0.5 M⊕ at all ages. The inferred disc masses are lower than those from disc detections around pre-main-sequence stars, which may indicate a depletion of solid mass. This may also be due to a change in disc opacity, though limited sensitivity means that it is not yet known what fraction of pre-main-sequence stars have discs with dust masses similar to debris disc levels. New, high-sensitivity detections are a path towards investigating the trends in dust mass evolution.
Kelvin-Helmholtz instability of counter-rotating discs
NASA Astrophysics Data System (ADS)
Quach, Dan; Dyda, Sergei; Lovelace, Richard V. E.
2015-01-01
Observations of galaxies and models of accreting systems point to the occurrence of counter-rotating discs where the inner part of the disc (r < r0) is corotating and the outer part is counter-rotating. This work analyses the linear stability of radially separated co- and counter-rotating thin discs. The strong instability found is the supersonic Kelvin-Helmholtz instability. The growth rates are of the order of or larger than the angular rotation rate at the interface. The instability is absent if there is no vertical dependence of the perturbation. That is, the instability is essentially three dimensional. The non-linear evolution of the instability is predicted to lead to a mixing of the two components, strong heating of the mixed gas, and vertical expansion of the gas, and annihilation of the angular momenta of the two components. As a result, the heated gas will free-fall towards the disc's centre over the surface of the inner disc.
Localization of the lumbar discs using machine learning and exact probabilistic inference.
Oktay, Ayse Betul; Akgul, Yusuf Sinan
2011-01-01
We propose a novel fully automatic approach to localize the lumbar intervertebral discs in MR images with PHOG based SVM and a probabilistic graphical model. At the local level, our method assigns a score to each pixel in target image that indicates whether it is a disc center or not. At the global level, we define a chain-like graphical model that represents the lumbar intervertebral discs and we use an exact inference algorithm to localize the discs. Our main contributions are the employment of the SVM with the PHOG based descriptor which is robust against variations of the discs and a graphical model that reflects the linear nature of the vertebral column. Our inference algorithm runs in polynomial time and produces globally optimal results. The developed system is validated on a real spine MRI dataset and the final localization results are favorable compared to the results reported in the literature.
Huang, Hai; Kornberg, Thomas B
2015-05-07
The flight muscles, dorsal air sacs, wing blades, and thoracic cuticle of the Drosophila adult function in concert, and their progenitor cells develop together in the wing imaginal disc. The wing disc orchestrates dorsal air sac development by producing decapentaplegic and fibroblast growth factor that travel via specific cytonemes in order to signal to the air sac primordium (ASP). Here, we report that cytonemes also link flight muscle progenitors (myoblasts) to disc cells and to the ASP, enabling myoblasts to relay signaling between the disc and the ASP. Frizzled (Fz)-containing myoblast cytonemes take up Wingless (Wg) from the disc, and Delta (Dl)-containing myoblast cytonemes contribute to Notch activation in the ASP. Wg signaling negatively regulates Dl expression in the myoblasts. These results reveal an essential role for cytonemes in Wg and Notch signaling and for a signal relay system in the myoblasts.
Real-time high-resolution PC-based system for measurement of errors on compact disks
NASA Astrophysics Data System (ADS)
Tehranchi, Babak; Howe, Dennis G.
1994-10-01
Hardware and software utilities are developed to directly monitor the Eight-to-Fourteen (EFM) demodulated data bytes at the input of a CD player's Cross-Interleaved Reed-Solomon Code (CIRC) block decoder. The hardware is capable of identifying erroneous data with single-byte resolution in the serial data stream read from a Compact Disc by a CDD 461 Philips CD-ROM drive. In addition, the system produces graphical maps that show the physical location of the measured errors on the entire disc, or via a zooming and planning feature, on user selectable local disc regions.
Wang, Qian; Xu, Zheng; Hu, Tingxing; Rehman, Hafeez Ur; Chen, Hong; Li, Zhongbin; Ding, Bo; Hu, Hongling
2014-01-01
Walnut agroforestry systems have many ecological and economic benefits when intercropped with cool-season species. However, decomposing leaf litter is one of the main sources of allelochemicals in such systems. In this study, lettuce (Lactuca sativa var. angustata) was grown in the soil incorporated with walnut leaf litter to assess its allelopathic activity. Lettuce growth and physiological processes were inhibited by walnut leaf litter, especially during early growth stage (1-2 euphylla period) or with large amount of litter addition. The plants treated by small amount of leaf litter recovered their growth afterwards, while the inhibition for 180 g leaf litter persisted until harvest. Twenty-eight compounds were identified in the leaf litter, and several of them were reported to be phytotoxic, which may be responsible for the stress induced by walnut leaf litter. Thus, for highest economic value of vegetables such as lettuce, excessive incorporation of leaf litter should be discouraged.
ELNET--The Electronic Library Database System.
ERIC Educational Resources Information Center
King, Shirley V.
1991-01-01
ELNET (Electronic Library Network), a Japanese language database, allows searching of index terms and free text terms from articles and stores the full text of the articles on an optical disc system. Users can order fax copies of the text from the optical disc. This article also explains online searching and discusses machine translation. (LRW)
Efficient radiative transfer techniques in hydrodynamic simulations
NASA Astrophysics Data System (ADS)
Mercer, A.; Stamatellos, D.; Dunhill, A.
2018-05-01
Radiative transfer is an important component of hydrodynamic simulations as it determines the thermal properties of a physical system. It is especially important in cases where heating and cooling regulate significant processes, such as in the collapse of molecular clouds, the development of gravitational instabilities in protostellar discs, disc-planet interactions, and planet migration. We compare two approximate radiative transfer methods which indirectly estimate optical depths within hydrodynamic simulations using two different metrics: (i) the gravitational potential and density of the gas (Stamatellos et al.), and (ii) the pressure scale-height (Lombardi et al.). We find that both methods are accurate for spherical configurations e.g. in collapsing molecular clouds and within clumps that form in protostellar discs. However, the pressure scale-height approach is more accurate in protostellar discs (low and high-mass discs, discs with spiral features, discs with embedded planets). We also investigate the β-cooling approximation which is commonly used when simulating protostellar discs, and in which the cooling time is proportional to the orbital period of the gas. We demonstrate that the use of a constant β cannot capture the wide range of spatial and temporal variations of cooling in protostellar discs, which may affect the development of gravitational instabilities, planet migration, planet mass growth, and the orbital properties of planets.
Diaz-Garcia, Sandra; Ahmed, Sara; Baonza, Antonio
2016-01-01
Regeneration is the ability that allows organisms to replace missing organs or lost tissue after injuries. This ability requires the coordinated activity of different cellular processes, including programmed cell death. Apoptosis plays a key role as a source of signals necessary for regeneration in different organisms. The imaginal discs of Drosophila melanogaster provide a particularly well-characterised model system for studying the cellular and molecular mechanisms underlying regeneration. Although it has been shown that signals produced by apoptotic cells are needed for homeostasis and regeneration of some tissues of this organism, such as the adult midgut, the contribution of apoptosis to disc regeneration remains unclear. Using a new method for studying disc regeneration in physiological conditions, we have defined the pattern of cell death in regenerating discs. Our data indicate that during disc regeneration, cell death increases first at the wound edge, but as regeneration progresses dead cells can be observed in regions far away from the site of damage. This result indicates that apoptotic signals initiated in the wound spread throughout the disc. We also present results which suggest that the partial inhibition of apoptosis does not have a major effect on disc regeneration. Finally, our results suggest that during disc regeneration distinct apoptotic signals might be acting simultaneously.
Total analysis systems with Thermochromic Etching Discs technology.
Avella-Oliver, Miquel; Morais, Sergi; Carrascosa, Javier; Puchades, Rosa; Maquieira, Ángel
2014-12-16
A new analytical system based on Thermochromic Etching Discs (TED) technology is presented. TED comprises a number of attractive features such as track independency, selective irradiation, a high power laser, and the capability to create useful assay platforms. The analytical versatility of this tool opens up a wide range of possibilities to design new compact disc-based total analysis systems applicable in chemistry and life sciences. In this paper, TED analytical implementation is described and discussed, and their analytical potential is supported by several applications. Microarray immunoassay, immunofiltration assay, solution measurement, and cell culture approaches are herein addressed in order to demonstrate the practical capacity of this system. The analytical usefulness of TED technology is herein demonstrated, describing how to exploit this tool for developing truly integrated analytical systems that provide solutions within the point of care framework.
Katsel, Pavel; Tan, Weilun; Abazyan, Bagrat; Davis, Kenneth L; Ross, Christopher; Pletnikov, Mikhail V; Haroutunian, Vahram
2011-01-01
Abnormalities in oligodendrocyte (OLG) differentiation and OLG gene expression deficit have been described in schizophrenia (SZ). Recent studies revealed a critical requirement for Disrupted-in-Schizophrenia 1 (DISC1) in neural development. Transgenic mice with forebrain restricted expression of mutant human DISC1 (ΔhDISC1) are characterized by neuroanatomical and behavioral abnormalities reminiscent of some features of SZ. We sought to determine whether the expression of ΔhDISC1 may influence the development of OLGs in this mouse model. OLG- and cell cycle-associated gene and protein expression were characterized in the forebrain of ΔhDISC1 mice during different stages of neurodevelopment (E15 and P1 days) and in adulthood. The results suggest that the expression of ΔhDISC1 exerts a significant influence on oligodendrocyte differentiation and function, evidenced by premature OLG differentiation and increased proliferation of their progenitors. Additional findings showed that neuregulin 1 and its receptors may be contributing factors to the observed upregulation of OLG genes. Thus, OLG function may be perturbed by mutant hDISC1 in a model system that provides new avenues for studying aspects of the pathogenesis of SZ. PMID:21605958
Yang, Lili; Mu, Liangshan; Huang, Kaiyu; Zhang, Tianyi; Mei, Zihan; Zeng, Wenrong; He, Jiawei; Chen, Wei; Liu, Xiaozheng; Ye, Xinjian; Yan, Zhihan
2016-12-13
The relationship between abdominal adiposity and disc degeneration remains largely uninvestigated. Here, we investigated the association between abdominal adipose tissue thickness and lumbar disc degeneration in a cross-sectional study of 2415 participants from The Second Affiliated Hospital of Wenzhou Medical University. All subjects were scanned with a 3T Magnetic Resonance Imaging system to evaluate the degree of lumbar disc degeneration. Multiple logistic regression analysis revealed that men in the highest quartiles for abdominal diameter (AD), sagittal diameter (SAD), and ventral subcutaneous thickness (VST) were at higher odds ratio for severe lumbar disc degeneration than men in the lowest quartiles. The adjusted model revealed that women in the highest quartiles for AD and SAD were also at higher odds ratio for severe lumbar disc degeneration than women in the lowest quartiles. Our results suggest that abdominal obesity might be one of underlying mechanisms of lumbar disc degeneration, and preventive strategies including weight control could be useful to reduce the incidence of lumbar disc degeneration. Prospective studies are needed to this confirm these results and to identify more deeper underlying mechanisms.
Effects of cryogenic treatment on the wear properties of brake discs
NASA Astrophysics Data System (ADS)
Nadig, D. S.; Shivakumar, P.; Anoop, S.; Chinmay, Kulkarni; Divine, P. V.; Harsha, H. P.
2017-02-01
Disc brakes are invariably used in all the automobiles either to reduce the rotational speed of the wheel or to hold the vehicle stationary. During the braking action, the kinetic energy is converted into heat which can result in high temperatures resulting in fading of brake effects. Brake discs produced out of martensite stainless steel (SS410) are expected to exhibit high wear resistance properties with low value of coefficient of friction. These factors increase the useful life of the brake discs with minimal possibilities of brake fade. To study the effects of cryogenic treatment on the wear behaviour, two types of brake discs were cryotreated at 98K for 8 and 24 hours in a specially developed cryotreatment system using liquid nitrogen. Wear properties of the untreated and cryotreated test specimens were experimentally determined using the pin on disc type tribometer (ASTM G99-95). Similarly, the Rockwell hardness (HRC) of the specimens were tested in a hardness tester in accordance with ASTM E18. In this paper, the effects of cryotreatment on the wear and hardness properties of untreated and cryotreated brake discs are presented. Results indicate enhancement of wear properties and hardness after cryogenic treatment compared with the normal brakes discs.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Castillo, E.; Vergara, M.; Moreno, Y.
2007-07-01
This paper describes the feasibility of an aerobic system (rotating biological contactor, RBC) and a biological anaerobic system (upward-flow anaerobic sludge bed reactor) at small scale for the treatment of a landfill leachate. In the first phase of the aerobic system study, a cyclic-batch RBC system was used to select perforated acetate discs among three different acetate disc configurations. These discs were chosen on the basis of high COD removal (65%) and biological stability. In the second phase, the RBC system (using four stages) was operated continuously at different hydraulic retention times (HRT), at different rotational speeds, and with varyingmore » organic concentrations of the influent leachate (2500-9000 mg L{sup -1}). Forty percent of the total surface area of each perforated disc was submerged in the leachate. A COD removal of about 52% was obtained at an HRT of 24 h and a rotational speed of 6 rpm. For the anaerobic system, the reactor was evaluated with a volumetric organic load of 3273 g-COD m{sup -3} day{sup -1} at an HRT of 54, 44, 39, 24 and 17 h. At these conditions, the system reached COD removal efficiencies of 62%, 61%, 59%, 44% and 24%, respectively.« less
Investigation of cryogenic rupture disc design
NASA Technical Reports Server (NTRS)
Keough, J. B.; Oldland, A. H.
1973-01-01
Rupture disc designs of both the active (command actuated) and passive (pressure ruptured) types were evaluated for performance characteristics at cryogenic temperatures and for capability to operate in a variety of cryogens, including gaseous and liquid fluorine. The test results, coupled with information from literature and industry searches, were used to establish a statement of design criteria and recommended practices for application of rupture discs to cryogenic rocket propellant feed and vent systems.
Mine Hoist Operator Training System. Phase I Report.
1978-11-01
Bodies of Knowledge Function Control speed of conveyances Hold conveyances in position Structural Components Types of brakes : * Disc * Drum - Jaw...Parallel motion Components of each type * Disc / drum * Pads/shoes * Operating mechanisms Operating mediums for braking * Hydraulic/pneumatic * Manual...SHAFT GUIDES Wood El BRAKES Steel Rails El Drum : Wire Rope: Jaw El Full Lock El Parallel Motion El Half Lock El Disc El LEVELS DRIVE MOTORS Single El
Blading System and Method For Controlling Structural Vibrations
NASA Technical Reports Server (NTRS)
Nguyen, Nhan (Inventor)
2000-01-01
A new blading system for controlling the structural vibrations in axial-flow compressors, turbines, or fans, as in aircraft engines and like turbomachines including a stator disc and a rotor disc is presented. The rotor disc defines several radial hubs that retain the rotor blading systems. Each blading system includes a blade formed of an airfoil, and a root attachment which is dimensioned to fit within, and to engage a corresponding hub. Viscoelastic dampers are selectively applied to the outer surfaces of the root attachment on which compressive or shear forces are likely to develop, intermediate the root attachment and the hub, for compression therebetween upon rotation of the rotor disc, in order to dampen structural vibrations. One advantage presented by the viscoelastic dampers lies in its simplicity, efficiency, cost effectiveness, and its ability to be retrofitted into existing turbomachines with minor surface treatment of the root attachments. Furthermore, since the dampers are not exposed to the inflowing airstream, they do not affect the aerodynamic performance of the turbomachine. Another feature of the damping system is that it provides a significant source of damping to minimize destructive structural vibrations, thereby increasing the durability of the turbomachine, and reducing acoustic noise accompanying high amplitude vibrations.
Forming spectroscopic massive protobinaries by disc fragmentation
NASA Astrophysics Data System (ADS)
Meyer, D. M.-A.; Kuiper, R.; Kley, W.; Johnston, K. G.; Vorobyov, E.
2018-01-01
The surroundings of massive protostars constitute an accretion disc which has numerically been shown to be subject to fragmentation and responsible for luminous accretion-driven outbursts. Moreover, it is suspected to produce close binary companions which will later strongly influence the star's future evolution in the Hertzsprung-Russel diagram. We present three-dimensional gravitation-radiation-hydrodynamic numerical simulations of 100 M⊙ pre-stellar cores. We find that accretion discs of young massive stars violently fragment without preventing the (highly variable) accretion of gaseous clumps on to the protostars. While acquiring the characteristics of a nascent low-mass companion, some disc fragments migrate on to the central massive protostar with dynamical properties showing that its final Keplerian orbit is close enough to constitute a close massive protobinary system, having a young high- and a low-mass components. We conclude on the viability of the disc fragmentation channel for the formation of such short-period binaries, and that both processes - close massive binary formation and accretion bursts - may happen at the same time. FU-Orionis-type bursts, such as observed in the young high-mass star S255IR-NIRS3, may not only indicate ongoing disc fragmentation, but also be considered as a tracer for the formation of close massive binaries - progenitors of the subsequent massive spectroscopic binaries - once the high-mass component of the system will enter the main-sequence phase of its evolution. Finally, we investigate the Atacama Large (sub-)Millimeter Array observability of the disc fragments.
A Herschel resolved far-infrared dust ring around HD 207129
NASA Astrophysics Data System (ADS)
Marshall, J. P.; Löhne, T.; Montesinos, B.; Krivov, A. V.; Eiroa, C.; Absil, O.; Bryden, G.; Maldonado, J.; Mora, A.; Sanz-Forcada, J.; Ardila, D.; Augereau, J.-Ch.; Bayo, A.; Del Burgo, C.; Danchi, W.; Ertel, S.; Fedele, D.; Fridlund, M.; Lebreton, J.; González-García, B. M.; Liseau, R.; Meeus, G.; Müller, S.; Pilbratt, G. L.; Roberge, A.; Stapelfeldt, K.; Thébault, P.; White, G. J.; Wolf, S.
2011-05-01
Context. Dusty debris discs around main sequence stars are thought to be the result of continuous collisional grinding of planetesimals in the system. The majority of these systems are unresolved and analysis of the dust properties is limited by the lack of information regarding the dust location. Aims: The Herschel DUNES key program is observing 133 nearby, Sun-like stars (<20 pc, FGK spectral type) in a volume limited survey to constrain the absolute incidence of cold dust around these stars by detection of far infrared excess emission at flux levels comparable to the Edgeworth-Kuiper belt (EKB). Methods: We have observed the Sun-like star HD 207129 with Herschel PACS and SPIRE. In all three PACS bands we resolve a ring-like structure consistent with scattered light observations. Using α Boötis as a reference point spread function (PSF), we deconvolved the images, clearly resolving the inner gap in the disc at both 70 and 100 μm. Results: We have resolved the dust-producing planetesimal belt of a debris disc at 100 μm for the first time. We measure the radial profile and fractional luminosity of the disc, and compare the values to those of discs around stars of similar age and/or spectral type, placing this disc in context of other resolved discs observed by Herschel/DUNES. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.
Birth of an Unusual Planetary System Artist Concept
2005-02-08
This artist animation shows a brown dwarf surrounded by a swirling disc of planet-building dust. NASA Spitzer Space Telescope spotted such a disc around a surprisingly low-mass brown dwarf, or failed star.
Stellar populations, stellar masses and the formation of galaxy bulges and discs at z < 3 in CANDELS
NASA Astrophysics Data System (ADS)
Margalef-Bentabol, Berta; Conselice, Christopher J.; Mortlock, Alice; Hartley, Will; Duncan, Kenneth; Kennedy, Rebecca; Kocevski, Dale D.; Hasinger, Guenther
2018-02-01
We present a multicomponent structural analysis of the internal structure of 1074 high-redshift massive galaxies at 1 < z < 3 from the CANDELS HST Survey. In particular, we examine galaxies best fitted by two structural components, and thus likely forming discs and bulges. We examine the stellar mass, star formation rates (SFRs) and colours of both the inner 'bulge' and outer 'disc' components for these systems using Spectral Energy Distribution (SED) information from the resolved ACS+WFC3 HST imaging. We find that the majority of both inner and outer components lie in the star-forming region of UVJ space (68 and 90 per cent, respectively). However, the inner portions, or the likely forming bulges, are dominated by dusty star formation. Furthermore, we show that the outer components of these systems have a higher SFR than their inner regions, and the ratio of SFR between 'disc' and 'bulge' increases at lower redshifts. Despite the higher SFR of the outer component, the stellar mass ratio of inner to outer component remains constant through this epoch. This suggests that there is mass transfer from the outer to inner components for typical two-component-forming systems, thus building bulges from discs. Finally, using Chandra data we find that the presence of an active galactic nucleus is more common in both one-component spheroid-like galaxies and two-component systems (13 ± 3 and 11 ± 2 per cent) than in one-component disc-like galaxies (3 ± 1 per cent), demonstrating that the formation of a central inner component likely triggers the formation of central massive black holes in these galaxies.
[In situ analysis of pathomechanisms of human intervertebral disc degeneration].
Weiler, C
2013-11-01
Low back pain is one of the major causes of pain and disability in the western world, with a constantly rising life-time prevalence of approximately 60-85 %. Degeneration of the intervertebral disc is believed to be a major cause of low back pain. Semiquantitative macroscopic and microscopic changes of the intervertebral disc were assessed and classified. Furthermore additional methods, such as immunohistochemistry, in situ hybridization and in situ zymography were used to analyze phenotypic cellular and matrix changes. We have developed and tested a practicable, valid and reliable histological classification system for lumbar discs which can serve as a morphological reference framework to allow more sophisticated molecular biological studies on the pathogenesis of ageing and degeneration of discs. Secondly, we were able to demonstrate that intrinsic (genetic) and extrinsic (e.g. overweight) factors have a profound effect on the process of disc degeneration. Cells with a notochord-like phenotype are present in a considerable fraction of adult lumbar intervertebral discs. The presence of these cells is associated with distinct features of (early) age-related disc degeneration. During the process of disc degeneration, the intervertebral disc shows a progressive and significant reduction in height due to tissue resorption. This matrix loss is related to an imbalance between matrix synthesis and degradation. During this process an inflammatory reaction takes place and resident disc cells are causatively involved. In summary, disc degeneration is a multifactorial disease with a strong intrinsic (hereditary) and extrinsic (e.g. mechanical factors) background. The process starts as early as in the second decade of life and shows high interindividual differences. The loss of regenerative capacity in the intervertebral disc is probably related to the loss of stem cells, e.g. notochord-like cells. Resident disc cells are involved in the inflammatory reaction with increased matrix degradation, resorption and reduced matrix synthesis.
Sack, Lawren; Scoffoni, Christine
2012-12-31
Water is a key resource, and the plant water transport system sets limits on maximum growth and drought tolerance. When plants open their stomata to achieve a high stomatal conductance (gs) to capture CO2 for photosynthesis, water is lost by transpiration(1,2). Water evaporating from the airspaces is replaced from cell walls, in turn drawing water from the xylem of leaf veins, in turn drawing from xylem in the stems and roots. As water is pulled through the system, it experiences hydraulic resistance, creating tension throughout the system and a low leaf water potential (Ψ(leaf)). The leaf itself is a critical bottleneck in the whole plant system, accounting for on average 30% of the plant hydraulic resistance(3). Leaf hydraulic conductance (K(leaf) = 1/ leaf hydraulic resistance) is the ratio of the water flow rate to the water potential gradient across the leaf, and summarizes the behavior of a complex system: water moves through the petiole and through several orders of veins, exits into the bundle sheath and passes through or around mesophyll cells before evaporating into the airspace and being transpired from the stomata. K(leaf) is of strong interest as an important physiological trait to compare species, quantifying the effectiveness of the leaf structure and physiology for water transport, and a key variable to investigate for its relationship to variation in structure (e.g., in leaf venation architecture) and its impacts on photosynthetic gas exchange. Further, K(leaf) responds strongly to the internal and external leaf environment(3). K(leaf) can increase dramatically with irradiance apparently due to changes in the expression and activation of aquaporins, the proteins involved in water transport through membranes(4), and K(leaf) declines strongly during drought, due to cavitation and/or collapse of xylem conduits, and/or loss of permeability in the extra-xylem tissues due to mesophyll and bundle sheath cell shrinkage or aquaporin deactivation(5-10). Because K(leaf) can constrain gs and photosynthetic rate across species in well watered conditions and during drought, and thus limit whole-plant performance they may possibly determine species distributions especially as droughts increase in frequency and severity(11-14). We present a simple method for simultaneous determination of K(leaf) and gs on excised leaves. A transpiring leaf is connected by its petiole to tubing running to a water source on a balance. The loss of water from the balance is recorded to calculate the flow rate through the leaf. When steady state transpiration (E, mmol • m(-2) • s(-1)) is reached, gs is determined by dividing by vapor pressure deficit, and K(leaf) by dividing by the water potential driving force determined using a pressure chamber (K(leaf)= E /- Δψ(leaf), MPa)(15). This method can be used to assess K(leaf) responses to different irradiances and the vulnerability of K(leaf) to dehydration(14,16,17).
Abdulah, Rizky; Milanda, Tiana; Sugijanto, Milyadi; Barliana, Melisa I; Diantini, Ajeng; Supratman, Unang; Subarnas, Anas
2017-01-01
Bacterial antimicrobial resistance is a major health problem worldwide. Plants consumed by non-human primates are potentially safe for humans. In this study, we examined the potential antibacterial properties of plants consumed by non-human primates in Indonesia. We studied the antibacterial properties of the leaf extracts of 34 primate-consumed plants against Escherichia coli and Bacillus subtilis in vitro. The plants were collected from the Pangandaran Conservation Area, West Java Province, Indonesia. The leaves were dried and then powdered by crushing and the potential active ingredients were extracted with 95% ethanol at room temperature for 24 hours. The obtained solvent was then dried at 50ºC under reduced pressure. The antibacterial properties of each product were then tested to determine the minimum inhibitory and minimum bactericidal concentrations using the broth microdilution technique and a disc diffusion test was also performed. The results show Kleinhovia hospita, Dillenia excelsa and Garcinia celebica had the best antibacterial properties against Escherichia coli and Ficus benjamina, Ficus altissima, and Elaeocarpus glaber had the best antibacterial properties against Bacillus subtilis. Some of the studied leaf extracts in our study have the potential to be developed into antibacterial medications and need to be studied further.
Protoplast Volume:Water Potential Relationship and Bound Water Fraction in Spinach Leaves 1
Santakumari, Mane; Berkowitz, Gerald A.
1989-01-01
Methods used to estimate the (nonosmotic) bound water fraction (BWF) (i.e. apoplast water) of spinach (Spinacia oleracea L.) leaves were evaluated. Studies using three different methods of pressure/volume (P/V) curve construction all resulted in a similar calculation of BWF; approximately 40%. The theoretically derived BWF, and the water potential (Ψw)/relative water content relationship established from P/V curves were used to establish the relationship between protoplast (i.e. symplast) volume and Ψw. Another method of establishing the protoplast volume/Ψw relationship in spinach leaves was compared with the results from P/V curve experiments. This second technique involved the vacuum infiltration of solutions at a range of osmotic potentials into discs cut from spinach leaves. These solutions contained radioactively labeled H2O and sorbitol. This dual label infiltration technique allowed for simultaneous measurement of the total and apoplast volumes in leaf tissue; the difference yielded the protoplast volume. The dual label infiltration experiments and the P/V curve constructions both showed that below −1 megapascals, protoplast volume decreases sharply with decreasing water potential; with 50% reduction in protoplast volume occurring at −1.8 megapascals leaf water potential. PMID:16666983
Rampino, Antonio; Walker, Rosie May; Torrance, Helen Scott; Anderson, Susan Maguire; Fazio, Leonardo; Di Giorgio, Annabella; Taurisano, Paolo; Gelao, Barbara; Romano, Raffaella; Masellis, Rita; Ursini, Gianluca; Caforio, Grazia; Blasi, Giuseppe; Millar, J Kirsty; Porteous, David John; Thomson, Pippa Ann; Bertolino, Alessandro; Evans, Kathryn Louise
2014-01-01
Cognitive dysfunction is central to the schizophrenia phenotype. Genetic and functional studies have implicated Disrupted-in-Schizophrenia 1 (DISC1), a leading candidate gene for schizophrenia and related psychiatric conditions, in cognitive function. Altered expression of DISC1 and DISC1-interactors has been identified in schizophrenia. Dysregulated expression of DISC1-interactome genes might, therefore, contribute to schizophrenia susceptibility via disruption of molecular systems required for normal cognitive function. Here, the blood RNA expression levels of DISC1 and DISC1-interacting proteins were measured in 63 control subjects. Cognitive function was assessed using neuropsychiatric tests and functional magnetic resonance imaging was used to assess the activity of prefrontal cortical regions during the N-back working memory task, which is abnormal in schizophrenia. Pairwise correlations between gene expression levels and the relationship between gene expression levels and cognitive function and N-back-elicited brain activity were assessed. Finally, the expression levels of DISC1, AKAP9, FEZ1, NDEL1 and PCM1 were compared between 63 controls and 69 schizophrenic subjects. We found that DISC1-interactome genes showed correlated expression in the blood of healthy individuals. The expression levels of several interactome members were correlated with cognitive performance and N-back-elicited activity in the prefrontal cortex. In addition, DISC1 and NDEL1 showed decreased expression in schizophrenic subjects compared to healthy controls. Our findings highlight the importance of the coordinated expression of DISC1-interactome genes for normal cognitive function and suggest that dysregulated DISC1 and NDEL1 expression might, in part, contribute to susceptibility for schizophrenia via disruption of prefrontal cortex-dependent cognitive functions.
Rampino, Antonio; Walker, Rosie May; Torrance, Helen Scott; Anderson, Susan Maguire; Fazio, Leonardo; Di Giorgio, Annabella; Taurisano, Paolo; Gelao, Barbara; Romano, Raffaella; Masellis, Rita; Ursini, Gianluca; Caforio, Grazia; Blasi, Giuseppe; Millar, J. Kirsty; Porteous, David John; Thomson, Pippa Ann; Bertolino, Alessandro; Evans, Kathryn Louise
2014-01-01
Cognitive dysfunction is central to the schizophrenia phenotype. Genetic and functional studies have implicated Disrupted-in-Schizophrenia 1 (DISC1), a leading candidate gene for schizophrenia and related psychiatric conditions, in cognitive function. Altered expression of DISC1 and DISC1-interactors has been identified in schizophrenia. Dysregulated expression of DISC1-interactome genes might, therefore, contribute to schizophrenia susceptibility via disruption of molecular systems required for normal cognitive function. Here, the blood RNA expression levels of DISC1 and DISC1-interacting proteins were measured in 63 control subjects. Cognitive function was assessed using neuropsychiatric tests and functional magnetic resonance imaging was used to assess the activity of prefrontal cortical regions during the N-back working memory task, which is abnormal in schizophrenia. Pairwise correlations between gene expression levels and the relationship between gene expression levels and cognitive function and N-back-elicited brain activity were assessed. Finally, the expression levels of DISC1, AKAP9, FEZ1, NDEL1 and PCM1 were compared between 63 controls and 69 schizophrenic subjects. We found that DISC1-interactome genes showed correlated expression in the blood of healthy individuals. The expression levels of several interactome members were correlated with cognitive performance and N-back-elicited activity in the prefrontal cortex. In addition, DISC1 and NDEL1 showed decreased expression in schizophrenic subjects compared to healthy controls. Our findings highlight the importance of the coordinated expression of DISC1-interactome genes for normal cognitive function and suggest that dysregulated DISC1 and NDEL1 expression might, in part, contribute to susceptibility for schizophrenia via disruption of prefrontal cortex-dependent cognitive functions. PMID:24940743
The Gas Content Of Protoplanetary Herbig Ae/be Discs As Seen With Herschel
NASA Astrophysics Data System (ADS)
Meeus, Gwendolyn; Herschel OTKP, GASPS; Dent, B.
2011-09-01
The mechanisms determining planet formation are not (yet) well-understood. Primordial protoplanetary discs consist 99% out of gas, and only 1% out of dust. With time, those discs are believed to evolve from a flaring geometry into a flat geometry, as the initially small dust grains grow to larger sizes and settle towards the mid-plane. In the mean time, the gas will disperse, until so little is left that giant planets no longer can form. As an important piece of the puzzle of planet formation, it is important to understand the influence of the gas heating/cooling processes on the young disc structure, its chemical composition and finally how fast gas gets dispersed. In this talk, we study the protoplanetary discs around Herbig Ae/Be stars, young objects of intermediate mass, in the context of its gas content. We present Herschel PACS spectroscopic observations for a sample that was obtained within the GASPS (Gas in Protoplanetary Systems) Open Time Key Project, concentrating on the detection and characterisation of emission lines of the [OI], [CII], and CO, tracing the disc between 5 and 500 AU. We look for correlations between the observed line fluxes and stellar properties such as effective temperature, Halpha emission, accretion rates and UV flux, as well as the disc properties: degree of flaring, presence and strength of PAH emission and disc mass. We will present a few cases to show how simultaneous modeling (using the thermo-chemical disc code ProDiMo) of the atomic fine structure lines and both molecular lines can constrain the disc gas mass, once the disc structure is derived. Finally, we compare our gas line observations with those of young debris disc stars, for which the HAEBE stars are thought to be progenitors.
Electromagnetic backscattering from a random distribution of lossy dielectric scatterers
NASA Technical Reports Server (NTRS)
Lang, R. H.
1980-01-01
Electromagnetic backscattering from a sparse distribution of discrete lossy dielectric scatterers occupying a region 5 was studied. The scatterers are assumed to have random position and orientation. Scattered fields are calculated by first finding the mean field and then by using it to define an equivalent medium within the volume 5. The scatterers are then viewed as being embedded in the equivalent medium; the distorted Born approximation is then used to find the scattered fields. This technique represents an improvement over the standard Born approximation since it takes into account the attenuation of the incident and scattered waves in the equivalent medium. The method is used to model a leaf canopy when the leaves are modeled by lossy dielectric discs.
DISC BRAKE SYSTEM (CENTER), INCLUDING BELT DRIVE TO SECONDARY GENERAL ...
DISC BRAKE SYSTEM (CENTER), INCLUDING BELT DRIVE TO SECONDARY GENERAL MOTORS ENGINE (LEFT)AND FERREL REDUCTION GEAR CONNECTION TO ALLIS-CHALMERS DIESEL ENGINE (RIGHT), LOOKING NORTH. NOTE TORQUE CONVERTER (TOP) AND THROTTLE (BELOW) LINES CONNECTING TO PRIMARY ENGINE. - Mad River Glen, Single Chair Ski Lift, 62 Mad River Glen Resort Road, Fayston, Washington County, VT
A study of a direct-injection stratified-charge rotary engine for motor vehicle application
NASA Astrophysics Data System (ADS)
Kagawa, Ryoji; Okazaki, Syunki; Somyo, Nobuhiro; Akagi, Yuji
1993-03-01
A study of a direct-injection stratified-charge system (DISC), as applied to a rotary engine (RE) for motor vehicle usage, was undertaken. The goals of this study were improved fuel consumption and reduced exhaust emissions. These goals were thought feasible due to the high thermal efficiency associated with the DISC-RE. This was the first application of this technology to a motor vehicle engine. Stable ignition and ideal stratification systems were developed by means of numerical calculations, air-fuel mixture measurements, and actual engine tests. The use of DISC resulted in significantly improved fuel consumption and reduced exhaust emissions. The use of an exhaust gas recirculating system was studied and found to be beneficial in NOx reduction.
The formation of bulges, discs and two-component galaxies in the CANDELS Survey at z < 3
NASA Astrophysics Data System (ADS)
Margalef-Bentabol, Berta; Conselice, Christopher J.; Mortlock, Alice; Hartley, Will; Duncan, Kenneth; Ferguson, Harry C.; Dekel, Avishai; Primack, Joel R.
2016-09-01
We examine a sample of 1495 galaxies in the CANDELS fields to determine the evolution of two-component galaxies, including bulges and discs, within massive galaxies at the epoch 1 < z < 3 when the Hubble sequence forms. We fit all of our galaxies' light profiles with a single Sérsic fit, as well as with a combination of exponential and Sérsic profiles. The latter is done in order to describe a galaxy with an inner and an outer component, or bulge and disc component. We develop and use three classification methods (visual, F-test and the residual flux fraction) to separate our sample into one-component galaxies (disc/spheroids-like galaxies) and two-component galaxies (galaxies formed by an `inner part' or bulge and an `outer part' or disc). We then compare the results from using these three different ways to classify our galaxies. We find that the fraction of galaxies selected as two-component galaxies increases on average 50 per cent from the lowest mass bin to the most massive galaxies, and decreases with redshift by a factor of 4 from z = 1 to 3. We find that single Sérsic `disc-like' galaxies have the highest relative number densities at all redshifts, and that two-component galaxies have the greatest increase and become at par with Sérsic discs by z = 1. We also find that the systems we classify as two-component galaxies have an increase in the sizes of their outer components, or `discs', by about a factor of 3 from z = 3 to 1.5, while the inner components or `bulges' stay roughly the same size. This suggests that these systems are growing from the inside out, whilst the bulges or protobulges are in place early in the history of these galaxies. This is also seen to a lesser degree in the growth of single `disc-like' galaxies versus `spheroid-like' galaxies over the same epoch.
Utilizing Remote Sensing Data to Ascertain Soil Moisture Applications and Air Quality Conditions
NASA Technical Reports Server (NTRS)
Leptoukh, Gregory; Kempler, Steve; Teng, William; Friedl, Lawrence; Lynnes, Chris
2009-01-01
Recognizing the significance of NASA remote sensing Earth science data in monitoring and better understanding our planet's natural environment, NASA Earth Applied Sciences has implemented the 'Decision Support Through Earth Science Research Results' program. Several applications support systems through collaborations with benefiting organizations have been implemented. The Goddard Earth Sciences Data and Information Services Center (GES DISC) has participated in this program on two projects (one complete, one ongoing), and has had opportune ad hoc collaborations utilizing NASA Earth science data. GES DISC's understanding of Earth science missions and resulting data and information enables the GES DISC to identify challenges that come with bringing science data to research applications. In this presentation we describe applications research projects utilizing NASA Earth science data and a variety of resulting GES DISC applications support system project experiences. In addition, defining metrics that really evaluate success will be exemplified.
Observing the On-going Formation of Planets and its Effects on Their Parent Discs
NASA Astrophysics Data System (ADS)
Willson, Matthew Alexander
2017-06-01
As the number of known exoplanetary systems has grown, it has become increasing apparent that our current understanding of planet formation is insufficient to explain the broad but distinct distributions of planets and planetary systems we observe. In particular, constructing a coherent model of planetary formation and migration within a circumstellar disc which is capable of producing both hot Jupiters or Solar System-like planetary system is high challenging. Resolved observations of where planets form and how they influence their parent discs provides essential information for tackling this important question. A promising technique for detecting close-in companions is Sparse Aperture Masking (SAM). The technique uses a mask to transform a single aperture telescope into a compact interferometric array capable of reliably detecting point sources at the diffraction limit or closer to a bright star with superior contrasts than extreme AO systems at the cost of smaller fields of view. Applying image reconstruction techniques to the interferometric information allows an observer to recover detailed structure in the circumstellar material. In this thesis I present work on the interpretation of SAM interferometry data on protoplanetary discs through the simulation of a number of scenarios expected to be commonly seen, and the application of this technique to a number of objects. Analysing data taken as part of a SAM survey of transitional and pre-transitional discs using the Keck-II/NIRC2 instrument, I detected three companion candidates within the discs of DM Tau, LkHα 330, and TW Hya, and resolved a gap in the disc around FP Tau as indicated by flux from the disc rim. The location of all three of the companions detected as part of the survey are positioned in interesting regions of their parent discs. The candidate, LkHα 330 b is a potentially cavity opening companion due to its close radial proximity to the inner rim of the outer disc. DM Tau b is located immediately outside of a ring of dusty material largely responsible for the NIR comment of the disc SED, similar to TW Hya b located in a shallow gap in the dust disc outside another ring of over-dense dusty material which bounds a deep but narrow gap. Both of these companion candidates maybe migrating cores which are feeding from the enriched ring of material. I conducted a more extensive study of the pre-transitional disc, V1247 Ori, covering three epochs and the H-, K- and L-wavebands. Complementary observations with VLT/SPHERE in Hα and continuum plus SMA observations in CO (2-1) and continuum were performed. The orientation and geometry of the outer disc was recovered with the SMA data and determine the direction of rotation. We image the inner rim of the outer disc in L-band SAM data, recovering the rim in all three epochs. Combining all three data sets together we form a detailed image of the rim. In H- and K-band SAM data we observe the motion of a close-in companion candidate. This motion was found to be too large to be adequately explained through a near-circular Keplerian orbit within the plane of the disc around the central star. Hence an alternate hypothesis had to be developed. I postulated that the fitted position of the companion maybe influenced by the emission from the disc rim seen in the L-band SAM data. I constructed a suite of model SAM data sets of a companion and a disc rim and found that under the right conditions the fitted separation of a companion will be larger than the true separation. Under these conditions we find the motion of the companion candidate to be consistent with a near-circular Keplerian orbit within the plane of the disc at a semi-major axis of ˜6 au. The Hα data lack the necessary resolution to confirm the companion as an accreting body, but through the high contrast sensitivities enabled by the state of the art SPHERE instrument I was able to rule out any other accreting body within the gap, unless deeply embedded by the sparse population of MIR emitting dust grains previously inferred to reside within the gap. Through the combination of SAM and SMA data we constrain the 3-D orientation of the disc, and through multi-wavelength SAM observation identify a close-in companion potentially responsible for the gap clearing and asymmetric arm structures seen in previous observations of this target. During my PhD I have contributed to the field of planet formation through the identification of four new candidate protoplanets observed in the discs of pre-main sequence stars. To do so I have quantified the confidence levels of companion fits to SAM data sets and formed synthetic data from models of asymmetric structures seen in these discs. I have described for the first time the effects of extended sources of emission on the fitted results of companion searches within interferometric data sets. I have combined SAM data sets from two separate telescopes with different apertures and masks to produce reconstructed image of an illuminated disc rim with superior uv-cover! age. I have used the expertise I have developed in this field to contribute to a number of other studies, including the study of the young star TYC 8241 2652 1, resulting in the rejection of a sub-stellar companion as the cause of the rapid dispersal of the star`s disc. The companion candidates I have identified here should be followed up to confirm their presence and nature as accreting protoplanets. Objects such as these will provide the opportunity for more detailed study of the process of planet formation in the near future with the next generation of instruments in the JWST and E-ELT.
Ginseng leaf-stem: bioactive constituents and pharmacological functions
Wang, Hongwei; Peng, Dacheng; Xie, Jingtian
2009-01-01
Ginseng root is used more often than other parts such as leaf stem although extracts from ginseng leaf-stem also contain similar active ingredients with pharmacological functions. Ginseng's leaf-stems are more readily available at a lower cost than its root. This article reviews the pharmacological effects of ginseng leaf-stem on some diseases and adverse effects due to excessive consumption. Ginseng leaf-stem extract contains numerous active ingredients, such as ginsenosides, polysaccharides, triterpenoids, flavonoids, volatile oils, polyacetylenic alcohols, peptides, amino acids and fatty acids. The extract contains larger amounts of the same active ingredients than the root. These active ingredients produce multifaceted pharmacological effects on the central nervous system, as well as on the cardiovascular, reproductive and metabolic systems. Ginseng leaf-stem extract also has anti-fatigue, anti-hyperglycemic, anti-obesity, anti-cancer, anti-oxidant and anti-aging properties. In normal use, ginseng leaf-stem extract is quite safe; adverse effects occur only when it is over dosed or is of poor quality. Extracts from ginseng root and leaf-stem have similar multifaceted pharmacological activities (for example central nervous and cardiovascular systems). In terms of costs and source availability, however, ginseng leaf-stem has advantages over its root. Further research will facilitate a wider use of ginseng leaf-stem. PMID:19849852
NASA Astrophysics Data System (ADS)
Cridland, A. J.; Pudritz, Ralph E.; Birnstiel, Tilman; Cleeves, L. Ilsedore; Bergin, Edwin A.
2017-08-01
We present the next step in a series of papers devoted to connecting the composition of the atmospheres of forming planets with the chemistry of their natal evolving protoplanetary discs. The model presented here computes the coupled chemical and dust evolution of the disc and the formation of three planets per disc model. Our three canonical planet traps produce a Jupiter near 1 AU, a Hot Jupiter and a Super-Earth. We study the dependence of the final orbital radius, mass, and atmospheric chemistry of planets forming in disc models with initial disc masses that vary by 0.02 M⊙ above and below our fiducial model (M_{disc,0} = 0.1 M_{⊙}). We compute C/O and C/N for the atmospheres formed in our three models and find that C/Oplanet ˜ C/O_{disc}, which does not vary strongly between different planets formed in our model. The nitrogen content of atmospheres can vary in planets that grow in different disc models. These differences are related to the formation history of the planet, the time and location that the planet accretes its atmosphere, and are encoded in the bulk abundance of NH3. These results suggest that future observations of atmospheric NH3 and an estimation of the planetary C/O and C/N can inform the formation history of particular planetary systems.
Garip, Hasan; Tufekcioglu, Sukran; Kaya, Emre
2018-01-01
Objectives: To analyze the relationships between temporalis and masseter muscle hypertrophy and temporomandibular joint (TMJ) disc displacement in patients with severe bruxism using magnetic resonance imaging (MRI). Methods: This retrospective study included 100 patients with severe bruxism, referred to the Department of Oral and Maxillofacial Surgery, University of Marmara and Istanbul Medipol University, Istanbul, Turkey, between January 2015 and December 2016. Patients underwent TMJ MRI with a 1.5-T system in open and closed mouth positions. The masseter and temporalis muscles were measured in the axial plane when the patient’s mouth was closed. Results: At its thinnest, the disc averaged was 1.11±0.24 mm. At their thickest, the masseter averaged was 13.65±2.19 mm and temporalis muscles was 12.98±2.4 mm. Of the discs, 24% were positioned normally, 74% were positioned anteriorly, and 2% were positioned posteriorly. The temporalis muscle was significantly thicker in patients with normally positioned discs than in those with anteriorly positioned discs (p=0.035). Conclusions: The temporalis muscle was significantly thicker in patients with normally positioned discs than in those with anteriorly positioned discs (p=0.035). Additional studies should be conducted to evaluate the relationships between all masticatory and surrounding muscles and disc movements in patients with bruxism. PMID:29332113
Oscillations of Static Discs around Schwarzschild Black Holes: Effect of Self-Gravitation
NASA Astrophysics Data System (ADS)
Semerák, Oldřich; Žáček, Miroslav
2000-12-01
The oscillations of accretion-disc matter about roughly circular motion may produce a quasi-periodic variation in the observed signal (Ipser 1996, AAA 65.067.047). They were studied theoretically on non-gravitating, test discs, in a pseudo-Newtonian manner as well as in general relativity, both in static and in stationary fields. The present paper shows how the radial profiles of oscillation frequencies can be modified by the self-gravity of the disc. Exact superpositions of a Schwarzschild black hole with the Lemos and Letelier (1994, AAA 61.067.077) annular discs (static thin discs obtained by inversion of the first Morgan-Morgan solution) are considered to be simple (static) models of an accretion system. Both the epicyclic and perpendicular frequencies are plotted against the Schwarzschild radius, the circumferential radius, and the proper distance from the horizon. The curves indicate that in the innermost parts more massive discs are more stable with respect to horizontal perturbations, whereas they are less stable with respect to vertical perturbations. In the case of a sequence of discs interpretable as counter-rotating particles on stable time-like circular geodesics and having their inner rims just on marginally stable circular orbits, oscillations of the inner parts get faster with increasing disc mass; the maximum of the epicyclic frequency, important for trapping of the low-frequency modes near the inner radius, moves to smaller radii and becomes somewhat higher.
Circumbinary discs: Numerical and physical behaviour
NASA Astrophysics Data System (ADS)
Thun, Daniel; Kley, Wilhelm; Picogna, Giovanni
2017-08-01
Aims: Discs around a central binary system play an important role in star and planet formation and in the evolution of galactic discs. These circumbinary discs are strongly disturbed by the time varying potential of the binary system and display a complex dynamical evolution that is not well understood. Our goal is to investigate the impact of disc and binary parameters on the dynamical aspects of the disc. Methods: We study the evolution of circumbinary discs under the gravitational influence of the binary using two-dimensional hydrodynamical simulations. To distinguish between physical and numerical effects we apply three hydrodynamical codes. First we analyse in detail numerical issues concerning the conditions at the boundaries and grid resolution. We then perform a series of simulations with different binary parameters (eccentricity, mass ratio) and disc parameters (viscosity, aspect ratio) starting from a reference model with Kepler-16 parameters. Results: Concerning the numerical aspects we find that the length of the inner grid radius and the binary semi-major axis must be comparable, with free outflow conditions applied such that mass can flow onto the central binary. A closed inner boundary leads to unstable evolutions. We find that the inner disc turns eccentric and precesses for all investigated physical parameters. The precession rate is slow with periods (Tprec) starting at around 500 binary orbits (Tbin) for high viscosity and a high aspect ratio H/R where the inner hole is smaller and more circular. Reducing α and H/R increases the gap size and Tprec reaches 2500 Tbin. For varying binary mass ratios qbin the gap size remains constant, whereas Tprec decreases with increasing qbin. For varying binary eccentricities ebin we find two separate branches in the gap size and eccentricity diagram. The bifurcation occurs at around ecrit ≈ 0.18 where the gap is smallest with the shortest Tprec. For ebin lower and higher than ecrit, the gap size and Tprec increase. Circular binaries create the most eccentric discs. Movies associated to Figs. 1 and 8 are available at http://www.aanda.org
Proto-planetary disc evolution and dispersal
NASA Astrophysics Data System (ADS)
Rosotti, Giovanni Pietro
2015-05-01
Planets form from gas and dust discs in orbit around young stars. The timescale for planet formation is constrained by the lifetime of these discs. The properties of the formed planetary systems depend thus on the evolution and final dispersal of the discs, which is the main topic of this thesis. Observations reveal the existence of a class of discs called "transitional", which lack dust in their inner regions. They are thought to be the last stage before the complete disc dispersal, and hence they may provide the key to understanding the mechanisms behind disc evolution. X-ray photoevaporation and planet formation have been studied as possible physical mechanisms responsible for the final dispersal of discs. However up to now, these two phenomena have been studied separately, neglecting any possible feedback or interaction. In this thesis we have investigated what is the interplay between these two processes. We show that the presence of a giant planet in a photo-evaporating disc can significantly shorten its lifetime, by cutting the inner regions from the mass reservoir in the exterior of the disc. This mechanism produces transition discs that for a given mass accretion rate have larger holes than in models considering only X-ray photo-evaporation, constituting a possible route to the formation of accreting transition discs with large holes. These discs are found in observations and still constitute a puzzle for the theory. Inclusion of the phenomenon called "thermal sweeping", a violent instability that can destroy a whole disc in as little as 10 4 years, shows that the outer disc left can be very short-lived (depending on the X-ray luminosity of the star), possibly explaining why very few non accreting transition discs are observed. However the mechanism does not seem to be efficient enough to reconcile with observations. In this thesis we also show that X-ray photo-evaporation naturally explains the observed correlation between stellar masses and accretion rates and is therefore the ideal candidate for driving disc evolution. Another process that can influence discs is a close encounter with another star. In this thesis we develop a model to study the effect of stellar dynamics in the natal stellar cluster on the discs, following for the first time at the same time the stellar dynamics together with the evolution of the discs. We find that, although close encounters with stars are unlikely to change significantly the mass of a disc, they can change substantially its size, hence imposing an upper limit on the observed disc radii. Finally, we investigated in this thesis whether discs can be reformed after their dispersal. If a star happens to be in a region that is currently forming stars, it can accrete material from the interstellar medium. This mechanism may result in the production of "second generation" discs such that in a given star forming region a few percent of stars may still possess a disc, in tentative agreement with observations of so called "old accretors", which are difficult to explain within the current paradigm of disc evolution and dispersal.
Growth and evolution of satellites in a Jovian massive disc
NASA Astrophysics Data System (ADS)
Moraes, R. A.; Kley, W.; Vieira Neto, E.
2018-03-01
The formation of satellite systems in circum-planetary discs is considered to be similar to the formation of rocky planets in a proto-planetary disc, especially super-Earths. Thus, it is possible to use systems with large satellites to test formation theories that are also applicable to extrasolar planets. Furthermore, a better understanding of the origin of satellites might yield important information about the environment near the growing planet during the last stages of planet formation. In this work, we investigate the formation and migration of the Jovian satellites through N-body simulations. We simulated a massive, static, low-viscosity, circum-planetary disc in agreement with the minimum mass sub-nebula model prescriptions for its total mass. In hydrodynamic simulations, we found no signs of gaps, therefore type II migration is not expected. Hence, we used analytic prescriptions for type I migration, eccentricity and inclination damping, and performed N-body simulations with damping forces added. Detailed parameter studies showed that the number of final satellites is strong influenced by the initial distribution of embryos, the disc temperature, and the initial gas density profile. For steeper initial density profiles, it is possible to form systems with multiple satellites in resonance while a flatter profile favours the formation of satellites close to the region of the Galilean satellites. We show that the formation of massive satellites such as Ganymede and Callisto can be achieved for hotter discs with an aspect ratio of H/r ˜ 0.15 for which the ice line was located around 30RJ.
NASA Astrophysics Data System (ADS)
Faridah; Natalia; Lina, Maria; W, Hendig
2014-03-01
Suji (Pleomele angustifolia NE Brown) is one of the medicinal plants of the tribe of Liliaceae, empirically useful to treat coughs and respiratory diseases such as tuberculosis (TB) and pneumonia. In this study, ethanolic extract of suji leaves was tested its activity against bacteria that attacks the respiratory organs, namely Mycobacterium tuberculosis and Streptococcus pneumoniae, using a paper disc diffusion and dilution agar method. These extracts have activity in inhibiting the growth of M. tuberculosis at a concentration of 8 mg and against S. pneumoniae at a concentration of 4 mg. The fractions were tested their antibacterial activity against Streptococcus pneumoniae using paper disc diffusion method. The most active fraction was chosen based on the inhibition diameter. The fractions contained flavonoids, steroids, and essential oils. The precipitate isolated from the extraction process shows needle-shaped, white, cold and tasteless crystals. Moreover, the HPLC analysis of isolate revealed a single peak with a retention time of 7.183 minutes. The exact compounds in the isolate could not be determined but it was known the compounds contained the functional groups of alkene, alkane, C=O, -OH. Test results obtained from UV-Vis spectrophotometer provides maximum absorption at a wavelength of 203.0 nm.
Molecules in Protoplanetary HAEBE discs as seen with Herschel.
NASA Astrophysics Data System (ADS)
Meeus, G.
2011-05-01
The discovery of planets around other stars has revealed that planet formation is ubiquitous. However, the mechanisms determining planet formation are not (yet) well-understood. Primordial protoplanetary discs consist 99% out of gas, and only 1% out of dust. With time, those discs are believed to evolve from a flaring geometry into a flat geometry, as the initially small dust grains grow to larger sizes and settle towards the mid-plane. In the mean time, the gas will disperse, until so little is left that giant planets no longer can form. It is thus important to understand the chemical composition of the disc and the influence of the gas heating/cooling processes on the disc structure, and finally how gas gets dispersed as a pieces of the puzzle of planet formation. In this contribution, we study the protoplanetary discs around Herbig Ae/Be stars, young objects of intermediate mass, in the context of gas chemistry. We present Herschel PACS spectroscopic observations for a sample that was obtained within the GASPS (Gas in Protoplanetary Systems) Open Time Key Project, concentrating on the detection and characterisation of emission lines of the molecules H20, CO and CH+ (besides [OI] and [CII]), tracing the disc between 5 and 500 AU. We look for correlations between the observed line fluxes and stellar properties such as effective temperature, Halpha emission, accretion rates and UV flux, as well as the disc properties: degree of flaring, presence and strength of PAH emission and disc mass. We will present a few cases to show how simultaneous modeling (using the thermo-chemical disc code ProDiMo) of the atomic fine structure lines and both Space Telescope and ground-based molecular lines can constrain the disc gas mass, once the disc structure is derived (here with the radiative transfer code MCFost). Finally, we compare our gas line observations with those of young debris disc stars, for which the HAEBE stars are thought to be progenitors.
High-speed electromechanical chutter for imaging spectrographs
NASA Technical Reports Server (NTRS)
Nguyen, Quang-Viet (Inventor)
2005-01-01
The present invention presents a high-speed electromechanical shutter which has at least two rotary beam choppers that are synchronized using a phase-locked loop electronic control to reduce the duty cycle. These choppers have blade means that can comprise discs or drums, each having about 60 (+/- 15) slots which are from about 0.3 to about 0.8 mm wide and about 5 to about 20 nun long (radially) which are evenly distributed through out 360 deg, and a third rotary chopper which is optically aligned has a small number of slots, such as for example, 1 to 10 slots which are about 1 to about 2 mm wide and about 5 to about 20 mm long (radially). Further the blade means include phase slots that allow the blade means to be phase locked using a closed loop control circuit. In addition, in a preferred embodiment, the system also has a leaf shutter. Thus the invention preferably achieves a gate width of less than about 100 microseconds, using motors that operate at 3000 to 10,OOO rpm, and with a phase jitter of less than about 1.5 microseconds, and further using an aperture with more than about 75% optical transmission with a clear aperture of about 0.8 -10 nun. The system can be synchronized to external sources at 0 6 kHz lasers, data acquisition systems, and cameras.
High-speed electromechanical shutter for imaging spectrographs
NASA Technical Reports Server (NTRS)
Nguyen, Quang-Viet (Inventor)
2005-01-01
The present invention presents a high-speed electromechanical shutter which has at least two rotary beam choppers that are synchronized using a phase-locked loop electronic control to reduce the duty cycle. These choppers have blade means that can comprise discs or drums, each having about 60 (+/-15) slots which are from about 0.3 to about 0.8 mm wide and about 5 to about 20 mm long (radially) which are evenly distributed through out 360?, and a third rotary chopper which is optically aligned has a small number of slots, such as for example, 1 to 10 slots which are about 1 to about 2 mm wide and about 5 to about 20 mm long (radially). Further the blade means include phase slots that allow the blade means to be phase locked using a closed loop control circuit. In addition, in a preferred embodiment, the system also has a leaf shutter. Thus the invention preferably achieves a gate width of less than about 100 microseconds, using motors that operate at 3000 to 10,000 rpm, and with a phase jitter of less than about 1.5 microseconds, and further using an aperture with more than about 75% optical transmission with a clear aperture of about 0.8 mm?10 mm. The system can be synchronized to external sources at 0 6 kHz lasers, data acquisition systems, and cameras.
Design and Development of Micro-Power Generating Device for Biomedical Applications of Lab-on-a-Disc
Joseph, Karunan; Ibrahim, Fatimah; Cho, Jongman; Thio, Tzer Hwai Gilbert; Al-Faqheri, Wisam; Madou, Marc
2015-01-01
The development of micro-power generators for centrifugal microfluidic discs enhances the platform as a green point-of-care diagnostic system and eliminates the need for attaching external peripherals to the disc. In this work, we present micro-power generators that harvest energy from the disc’s rotational movement to power biomedical applications on the disc. To implement these ideas, we developed two types of micro-power generators using piezoelectric films and an electromagnetic induction system. The piezoelectric-based generator takes advantage of the film’s vibration during the disc’s rotational motion, whereas the electromagnetic induction-based generator operates on the principle of current generation in stacks of coil exposed to varying magnetic flux. We have successfully demonstrated that at the spinning speed of 800 revolutions per minute (RPM) the piezoelectric film-based generator is able to produce up to 24 microwatts using 6 sets of films and the magnetic induction-based generator is capable of producing up to 125 milliwatts using 6 stacks of coil. As a proof of concept, a custom made localized heating system was constructed to test the capability of the magnetic induction-based generator. The heating system was able to achieve a temperature of 58.62°C at 2200 RPM. This development of lab-on-a-disc micro power generators preserves the portability standards and enhances the future biomedical applications of centrifugal microfluidic platforms. PMID:26422249
Enormous disc of cool gas surrounding the nearby powerful radio galaxy NGC612 (PKS0131-36)
NASA Astrophysics Data System (ADS)
Emonts, B. H. C.; Morganti, R.; Oosterloo, T. A.; Holt, J.; Tadhunter, C. N.; van der Hulst, J. M.; Ojha, R.; Sadler, E. M.
2008-06-01
We present the detection of an enormous disc of cool neutral hydrogen (HI) gas surrounding the S0 galaxy NGC612, which hosts one of the nearest powerful radio sources (PKS0131-36). Using the Australia Telescope Compact Array, we detect MHI = 1.8 × 109Msolar of HI emission-line gas that is distributed in a 140-kpc wide disc-like structure along the optical disc and dust lane of NGC612. The bulk of the gas in the disc appears to be settled in regular rotation with a total velocity range of 850kms-1, although asymmetries in this disc indicate that perturbations are being exerted on part of the gas, possibly by a number of nearby companions. The HI disc in NGC612 suggests that the total mass enclosed by the system is Menc ~ 2.9 × 1012 sin-2 iMsolar, implying that this early-type galaxy contains a massive dark matter halo. We also discuss an earlier study by Holt et al. that revealed the presence of a prominent young stellar population at various locations throughout the disc of NGC612, indicating that this is a rare example of an extended radio source that is hosted by a galaxy with a large-scale star-forming disc. In addition, we map a faint HI bridge along a distance of 400kpc in between NGC612 and the gas-rich (MHI = 8.9 × 109Msolar) barred galaxy NGC619, indicating that likely an interaction between both systems occurred. From the unusual amounts of HI gas and young stars in this early-type galaxy, in combination with the detection of a faint optical shell and the system's high infrared luminosity, we argue that either ongoing or past galaxy interactions or a major merger event are a likely mechanism for the triggering of the radio source in NGC612. This paper is part of an ongoing study to map the large-scale neutral hydrogen properties of nearby radio galaxies and it presents the first example of large-scale HI detected around a powerful Fanaroff-Riley type II (FR-II) radio galaxy. The HI properties of the FR-II radio galaxy NGC612 are very similar to those found for low-power compact radio sources, but different from those of extended Fanaroff-Riley type I (FR-I) sources.
The rotation of discs around neutron stars: dependence on the Hall diffusion
NASA Astrophysics Data System (ADS)
Faghei, Kazem; Salehi, Fatemeh
2018-01-01
In this paper, we study the dynamics of a geometrically thin, steady and axisymmetric accretion disc surrounding a rotating and magnetized star. The magnetic field lines of star penetrate inside the accretion disc and are twisted due to the differential rotation between the magnetized star and the disc. We apply the Hall diffusion effect in the accreting plasma, because of the Hall diffusion plays an important role in both fully ionized plasma and weakly ionized medium. In the current research, we show that the Hall diffusion is also an important mechanism in accreting plasma around neutron stars. For the typical system parameter values associated with the accreting X-ray binary pulsar, the angular velocity of the inner regions of disc departs outstandingly from Keplerian angular velocity, due to coupling between the magnetic field of neutron star and the rotating plasma of disc. We found that the Hall diffusion is very important in inner disc and increases the coupling between the magnetic field of neutron star and accreting plasma. On the other word, the rotational velocity of inner disc significantly decreases in the presence of the Hall diffusion. Moreover, the solutions imply that the fastness parameter decreases and the angular velocity transition zone becomes broad for the accreting plasma including the Hall diffusion.
NASA Astrophysics Data System (ADS)
Kaufman, J.; Blaes, O. M.; Hirose, S.
2018-06-01
Warm Comptonization models for the soft X-ray excess in active galactic nuclei (AGN) do not self-consistently explain the relationship between the Comptonizing medium and the underlying accretion disc. Because of this, they cannot directly connect the fitted Comptonization temperatures and optical depths to accretion disc parameters. Since bulk velocities exceed thermal velocities in highly radiation pressure dominated discs, in these systems bulk Comptonization by turbulence may provide a physical basis in the disc itself for warm Comptonization models. We model the dependence of bulk Comptonization on fundamental accretion disc parameters, such as mass, luminosity, radius, spin, inner boundary condition, and α. In addition to constraining warm Comptonization models, our model can help distinguish contributions from bulk Comptonization to the soft X-ray excess from those due to other physical mechanisms, such as absorption and reflection. By linking the time variability of bulk Comptonization to fluctuations in the disc vertical structure due to magnetorotational instability (MRI) turbulence, our results show that observations of the soft X-ray excess can be used to study disc turbulence in the radiation pressure dominated regime. Because our model connects bulk Comptonization to 1D vertical structure temperature profiles in a physically intuitive way, it will be useful for understanding this effect in future simulations run in new regimes.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ross, N., E-mail: rossn2282@gmail.com; Kostylev, M., E-mail: mikhail.kostylev@uwa.edu.au; Stamps, R. L.
2014-09-21
Standing spin wave mode frequencies and linewidths in partially disordered perpendicular magnetized arrays of sub-micron Permalloy discs are measured using broadband ferromagnetic resonance and compared to analytical results from a single, isolated disc. The measured mode structure qualitatively reproduces the structure expected from the theory. Fitted demagnetizing parameters decrease with increasing array disorder. The frequency difference between the first and second radial modes is found to be higher in the measured array systems than predicted by theory for an isolated disc. The relative frequencies between successive spin wave modes are unaffected by reduction of the long-range ordering of discs inmore » the array. An increase in standing spin wave resonance linewidth at low applied magnetic fields is observed and grows more severe with increased array disorder.« less
Signatures of massive collisions in debris discs. A self-consistent numerical model
NASA Astrophysics Data System (ADS)
Kral, Q.; Thébault, P.; Augereau, J.-C.; Boccaletti, A.; Charnoz, S.
2015-01-01
Context. Violent stochastic collisional events have been invoked as a possible explanation for some debris discs displaying pronounced azimuthal asymmetries or having a luminosity excess exceeding that expected for systems at collisional steady-state. So far, no thorough modelling of the consequences of such stochastic events has been carried out, mainly because of the extreme numerical challenge of coupling the dynamical and collisional evolution of the released dust. Aims: We perform the first fully self-consistent modelling of the aftermath of massive breakups in debris discs. We follow the collisional and dynamical evolution of dust released after the breakup of a Ceres-sized body at 6 AU from its central star. We investigate the duration, magnitude, and spatial structure of the signature left by such a violent event, as well as its observational detectability. Methods: We use the recently developed LIDT-DD code, which handles the coupled collisional and dynamical evolution of debris discs. The main focus is placed on the complex interplay between destructive collisions, Keplerian dynamics, and radiation pressure forces. We use the GRaTer package to estimate the system's luminosity at different wavelengths. Results: The breakup of a Ceres-sized body at 6 AU creates an asymmetric dust disc that is homogenized by the coupled action of collisions and dynamics on a timescale of a few 105 years. After a transient period where it is very steep, the particle size distribution in the system relaxes to a collisional steady-state law after ~104 years. The luminosity excess in the breakup's aftermath should be detectable by mid-IR photometry, from a 30 pc distance, over a period of ~106 years that exceeds the duration of the asymmetric phase of the disc (a few 105 years). As for the asymmetric structures, we derive synthetic images for the VLT/SPHERE and JWST/MIRI instruments, showing that they should be clearly visible and resolved from a 10 pc distance. Images at 1.6 μm (marginally), 11.4, and 15.5 μm show the inner disc structures, while 23 μm images display the outer disc asymmetries.
SONS: The JCMT legacy survey of debris discs in the submillimetre
NASA Astrophysics Data System (ADS)
Holland, Wayne S.; Matthews, Brenda C.; Kennedy, Grant M.; Greaves, Jane S.; Wyatt, Mark C.; Booth, Mark; Bastien, Pierre; Bryden, Geoff; Butner, Harold; Chen, Christine H.; Chrysostomou, Antonio; Davies, Claire L.; Dent, William R. F.; Di Francesco, James; Duchêne, Gaspard; Gibb, Andy G.; Friberg, Per; Ivison, Rob J.; Jenness, Tim; Kavelaars, JJ; Lawler, Samantha; Lestrade, Jean-François; Marshall, Jonathan P.; Moro-Martin, Amaya; Panić, Olja; Phillips, Neil; Serjeant, Stephen; Schieven, Gerald H.; Sibthorpe, Bruce; Vican, Laura; Ward-Thompson, Derek; van der Werf, Paul; White, Glenn J.; Wilner, David; Zuckerman, Ben
2017-09-01
Debris discs are evidence of the ongoing destructive collisions between planetesimals, and their presence around stars also suggests that planets exist in these systems. In this paper, we present submillimetre images of the thermal emission from debris discs that formed the SCUBA-2 Observations of Nearby Stars (SONS) survey, one of seven legacy surveys undertaken on the James Clerk Maxwell Telescope between 2012 and 2015. The overall results of the survey are presented in the form of 850 μm (and 450 μm, where possible) images and fluxes for the observed fields. Excess thermal emission, over that expected from the stellar photosphere, is detected around 49 stars out of the 100 observed fields. The discs are characterized in terms of their flux density, size (radial distribution of the dust) and derived dust properties from their spectral energy distributions. The results show discs over a range of sizes, typically 1-10 times the diameter of the Edgeworth-Kuiper Belt in our Solar system. The mass of a disc, for particles up to a few millimetres in size, is uniquely obtainable with submillimetre observations and this quantity is presented as a function of the host stars' age, showing a tentative decline in mass with age. Having doubled the number of imaged discs at submillimetre wavelengths from ground-based, single-dish telescope observations, one of the key legacy products from the SONS survey is to provide a comprehensive target list to observe at high angular resolution using submillimetre/millimetre interferometers (e.g. Atacama Large Millimeter Array, Smithsonian Millimeter Array).
Out of the Dust, A Planet is Born Artist Concept
2004-05-27
In this artist's conception, a possible newfound planet spins through a clearing in a nearby star's dusty, planet-forming disc. This clearing was detected around the star CoKu Tau 4 by NASA's Spitzer Space Telescope. Astronomers believe that an orbiting massive body, like a planet, may have swept away the star's disc material, leaving a central hole. The possible planet is theorized to be at least as massive as Jupiter, and may have a similar appearance to what the giant planets in our own solar system looked like billions of years ago. A graceful ring, much like Saturn's, spins high above the planet's cloudy atmosphere. The ring is formed from countless small orbiting particles of dust and ice, leftovers from the initial gravitational collapse that formed the possible giant planet. If we were to visit a planet like this, we would have a very different view of the universe. The sky, instead of being the familiar dark expanse lit by distant stars, would be dominated by the thick disc of dust that fills this young planetary system. The view looking toward CoKu Tau 4 would be relatively clear, as the dust in the interior of the disc has fallen into the accreting star. A bright band would seem to surround the central star, caused by light scattered back by the dust in the disc. Looking away from CoKu Tau 4, the dusty disc would appear dark, blotting out light from all the stars in the sky except those which lie well above the plane of the disc. http://photojournal.jpl.nasa.gov/catalog/PIA05988
NASA Astrophysics Data System (ADS)
Wu, Meng-Ru; Fernández, Rodrigo; Martínez-Pinedo, Gabriel; Metzger, Brian D.
2016-12-01
We consider r-process nucleosynthesis in outflows from black hole accretion discs formed in double neutron star and neutron star-black hole mergers. These outflows, powered by angular momentum transport processes and nuclear recombination, represent an important - and in some cases dominant - contribution to the total mass ejected by the merger. Here we calculate the nucleosynthesis yields from disc outflows using thermodynamic trajectories from hydrodynamic simulations, coupled to a nuclear reaction network. We find that outflows produce a robust abundance pattern around the second r-process peak (mass number A ˜ 130), independent of model parameters, with significant production of A < 130 nuclei. This implies that dynamical ejecta with high electron fraction may not be required to explain the observed abundances of r-process elements in metal poor stars. Disc outflows reach the third peak (A ˜ 195) in most of our simulations, although the amounts produced depend sensitively on the disc viscosity, initial mass or entropy of the torus, and nuclear physics inputs. Some of our models produce an abundance spike at A = 132 that is absent in the Solar system r-process distribution. The spike arises from convection in the disc and depends on the treatment of nuclear heating in the simulations. We conclude that disc outflows provide an important - and perhaps dominant - contribution to the r-process yields of compact binary mergers, and hence must be included when assessing the contribution of these systems to the inventory of r-process elements in the Galaxy.
da Costa, Juliana B; Goncalves, Flavia; Ferracane, Jack L
2011-01-01
The purpose of this study was to evaluate surface finish and gloss of a two-step composite finishing/polishing (F/P) disc system compared with two multistep systems on five composites. Seventy-five disc-shaped composite specimens (D=10.0 mm, 2 mm thick, n=15 per composite) were made of microfill (Durafill-D), nanofill (Filtek Supreme-FS), nanohybrid (Premise-PR), and microhybrids (Filtek Z250-FZ, Esthet-EX). One side of each specimen was initially finished with a carbide bur. Five specimens of each resin composite were randomly assigned to receive full F/P by each of the disc systems: two-step (Enhance Flex NST-EF) and four-step (Sof-Lex-SL, Super-Snap-SS). Surface gloss was measured with a glossmeter and surface roughness was measured with a profilometer. Results were analyzed by two-way analysis of variance (ANOVA)/Tukey's (α<0.05). No difference in gloss was noted among the three F/P systems when used with D and EX; no difference between SL and EF when used with any composite, except for FS; and no difference between SL and SS when used with any composite. SL and EF showed similar surface roughness when used on all composites, except for EX. EF and SS showed similar surface roughness on PR. SL and SS showed similar surface roughness values on every composite, except for FZ. EF was capable of providing similar gloss and surface roughness to SL on four composites evaluated but was not able to produce as glossy or as smooth a surface as SS for three of the five composites.
Development of Ultrasound to Measure In-Vivo Dynamic Cervical Spine Intervertebral Disc Mechanics
2016-01-01
Award Number: W81XWH-13-1-0050 TITLE: Development of Ultrasound to Measure In-vivo Dynamic Cervical Spine Intervertebral Disc Mechanics PRINCIPAL...CONTRACT NUMBER W81XWH-13-1-0050 Development of Ultrasound to Measure In-vivo Dynamic Cervical Spine Intervertebral Disc Mechanics 5b. GRANT NUMBER 5c...elasticity during compression or tension. As a portable, low cost imaging modality, the dual ultrasound system quantified cervical spine IVD displacement and
Kulduk, Ahmet; Altun, Necdet S; Senkoylu, Alpaslan
2015-12-01
The primary purpose of dynamic stabilization is to preserve the normal range of motion (ROM) by restricting abnormal movement in the spine. Our aim was to analyze the effects of two different dynamic stabilization systems using finite element modeling (FEM). Coflex and Dynesys dynamic devices were modeled and implanted at the L4-L5 segment using virtual FEM. A 400 N compressive force combined with 6 N flexion, extension, bending and axial rotation forces was applied to the L3-4 and L4-5 segments. ROM and disc loading forces were analyzed. Both systems reduced ROM and disc loading forces at the implanted lumbar segment, with the exception of the Coflex interspinous device, which increased ROM by 19% and did not change disc-loading forces in flexion. The Coflex device prevented excessive disc loading, but increased ROM abnormally in flexion. Neither device provided satisfactory motion preservation or load sharing in other directions. Copyright © 2015 John Wiley & Sons, Ltd.
On-line damage detection in rotating machinery
NASA Astrophysics Data System (ADS)
Alkhalifa, Tareq Jawad
This work is concerned with a set of techniques to detect internal defects in uniform circular discs (rotors). An internal defect is intentionally manufactured in stereolithographic discs by a rapid prototyping process using cured resin SL 5170 material. The analysis and results presented here are limited to a uniform circular disc, with internal defects, mounted on a uniform flexible circular shaft. The setup is comprised of a Bently Nevada rotor kit connected to a data acquisition system. The rotor consists of a disc and shaft that is supported by journal bearings and is coupled to a motor by a rubber joint. Damage produces localized changes in the strain energy, which is quantified to characterize the damage. Based on previous research, the Strain Energy Damage Index (SEDI) is utilized to localize the damage due to strain energy differences between damaged and undamaged modes. To accomplish the objective, this work covers three types of analysis: finite element analysis, vibration analysis, and experimental modal analysis. Finite element analysis (using SDRC Ideas software) is performed to develop a multi-degree-of-freedom (MDOF) rotor system with internal damage, and its dynamic characteristics are investigated. The analysis is performed for two different types damage cases: radial damage and circular damage. Parametric study for radial damage and random noise to undamaged disc have been investigated to predict the effect of noise in the damage detection. The developed on-line damage detection technique for rotating equipment incorporates and couples both vibration analysis and experimental modal analysis. The dynamic investigation of the rotating discs (with and without defect) is conducted by vibration signal analysis (using proximity sensors, data acquisition and LabView). The vibration analysis provides a unique vibration signature for the damaged disc, which indicates the existence of the damage. The vibration data are acquired at different running speeds (1000, 2500, 5000 rpm). Then the dynamic investigation of non-rotating discs (with and without defect) is conducted by experimental modal analysis (using STAR software). While the vibration analysis detects and indicates the existence of damage while the disc is rotating, experimental modal analysis (using STAR and MATLAB software) provides the localization of damage through the modal parameters for a non-rotating disc. Both of the experimental diagnostic algorithms are based on measurement of the dynamic behavior of the damaged disc. The results are compared with the reference, or baseline, one, obtained initially for an undamaged disc. (Abstract shortened by UMI.)
Mozafari, Ali Akbar; Vafaee, Yavar; Karami, Edris
2015-07-01
An efficient and rapid in vitro propagation system for Satureja avromanica, a rare and endangered folk medicinal plant of Iran was developed through the shoot tip and leaf disc explants. Nodal and leaf explants from wild plants were established on MS and WPM media supplemented with BA, BAP and TDZ (0, 0.1, 0.5, 1, 1.5, 2, 5 and 10 mgl(-1)) alone or by application of BA and TDZ (0, 2, 5 and 10 mgl(-1)) in combination with IBA and 2,4-D (0, 0.1, 0.5 and 1 mgl(-1)), respectively. Based on results, the highest mean shoot number (6.21) was obtained on MS medium supplemented with 2 mgl(-1) BA. Regarding the shoot elongation, MS supplemented with 2 mgl(-1) TDZ and MS containing 5 mgl(-1) BA showed the longest shoots (4.82 and 4.39 cm, respectively) after 6 weeks of culture. As a matter of fact, increasing all three tested cytokinins levels led to enhancement of explant response frequency and regenerated shoot number. On the other side, WPM medium supplemented with 0.1 mgl(-1) IBA was found suitable for rooting of regenerated shoots. RAPD molecular analysis revealed genetic stability of in vitro raised plants. In conclusion, individual application of BA, BAP and TDZ were in favor of S. avromanica direct shoot regeneration while treatment media with a combination of IBA and BA as well as 2,4-D and TDZ resulted in callogenesis in most explants. Finally, the in vitro raised plantlets were acclimatized and successfully established in the greenhouse conditions. Our developed protocol can be employed for the large-scale micropropagation and conservation of S. avromanica as a threatened medicinal plant.
Parkinson, Richard J; Mian, Shahid; Bishop, Michael C; Gray, Trevor; Li, Geng; McArdle, Stephanie E B; Ali, Selman; Rees, Robert C
2003-06-15
DISC-HSV is a replication incompetent herpes simplex virus that is a highly efficient vector for the transduction of genes in vivo and in vitro. We examine the ability of DISC-HSV to infect human prostate cancer cell-lines and xenograft tumor models, and induce expression of reporter and therapeutic cytokine genes. Infection was confirmed by cellular staining for the beta-galactosidase reporter gene product, and by EM. Human GM-CSF production following DISC-hGMCSF infection was measured using ELISA. The metabolic activity of infected cells was determined by NADP/NADPH assay. Cell death was estimated by cell-cycle analysis using flow cytometry with propidium iodide staining. Infection of DU145, PC3 and LNCaP cells with DISC-HSV was dose dependent. Cells infected with DISC-hGM-CSF released significant levels of hGM-CSF for 3 days. NADP/NADPH assay suggested that infected cells continued to be metabolically active for 3 days post-infection, which was consistent with flow cytometry findings that cell death did not occur within 7 days of infection. Tumor xenografts injected with DISC-HSV expressed beta-galactosidase, and intracellular viral particles were demonstrated using EM. We have previously reported the rejection of established tumors following intra-tumoral injection of DISC-GMCSF. This study demonstrates the ability of DISC-HSV to infect prostate cancer and express GMCSF at significant levels. We suggest that prostate cancer is a potential target for therapy using DISC-HSV containing GM-CSF. Copyright 2003 Wiley-Liss, Inc.
Park, H-Yl; Hwang, Y S; Park, C K
2017-04-01
PurposeTo investigate the clinical characteristics according to the location of focal lamina cribrosa (LC) defects and its associated ocular features.Patients and methodsA total of 139 open-angle glaucoma patients underwent Spectralis optical coherence tomography (OCT) with enhanced depth imaging. Alterations in the contour of the LC were investigated to find focal LC defects. The location of the visible LC defect from the neural canal wall (far-peripheral and mid-peripheral) and clock-hour position (superotemporal, temporal and inferotemporal) were classified. Disc ovality ratio and disc-foveal angle were measured from disc and retinal nerve fiber layer (RNFL) photographs. The disc tilt degree was measured using a Heidelberg Retina Tomograph (HRT) III system. The en face OCT image of the disc scans was registered to the disc and RNFL photographs, to determine whether the focal LC defects corresponded spatially to the glaucomatous damage location.ResultsEyes with far-peripheral LC defects were significantly myopic and had a higher disc ovality ratio. The disc tilt degree obtained by HRT revealed significant temporal disc tilt in eyes with temporal LC defects (P<0.001). Eyes with inferotemporal LC defects had a significantly larger disc-foveal angle (P=0.027). The inferotemporal LC defects corresponded to the location of glaucomatous damage in 81.6%; however, only 46.2% of eyes with a superotemporal LC defect and 3.2% of eyes with a temporal LC defect corresponded spatially with the glaucomatous damage location.ConclusionsThe clinical characteristics and association with glaucomatous damage location were different according to the location of focal LC defect.
Disc herniations in the national football league.
Gray, Benjamin L; Buchowski, Jacob M; Bumpass, David B; Lehman, Ronald A; Mall, Nathan A; Matava, Matthew J
2013-10-15
Retrospective analysis of a prospectively collected database. To determine the overall incidence, location, and type of disc herniations in professional football players to target treatment issues and prevention. Disc herniations represent a common and debilitating injury to the professional athlete. The NFL's (National Football League's) Sports Injury Monitoring System is a surveillance database created to monitor the league for all injuries, including injuries to the cervical, thoracic, and lumbar spine. A retrospective analysis was performed on all disc herniations to the cervical, thoracic, and lumbar spine during a 12-season period (2000-2012) using the NFL's surveillance database. The primary data points included the location of the injury, player position, activity at time of injury, and playing time lost due to injury. During the 12 seasons, 275 disc herniations occurred in the spine. In regard to location, 76% occurred in the lumbar spine and most frequently affected the L5-S1 disc. The offensive linemen were most frequently injured. As expected, blocking was the activity that caused most injuries. Lumbar disc herniations rose in prevalence and had a mean loss of playing time of more than half the season (11 games). Thoracic disc herniations led to the largest mean number of days lost overall, whereas players with cervical disc herniations missed the most practices. Disc herniations represent a significant cause of morbidity in the NFL. Although much attention is placed on spinal cord injuries, preventive measures targeting the cervical, thoracic, and lumbar spine may help to reduce the overall incidence of these debilitating injuries.Level of Evidence: N/A.
Disc herniations in the National Football League.
Gray, Benjamin L; Buchowski, Jacob M; Bumpass, David B; Lehman, Ronald A; Mall, Nathan A; Matava, Matthew J
2013-10-15
Retrospective analysis of a prospectively collected database. To determine the overall incidence, location, and type of disc herniations in professional football players to target treatment issues and prevention. Disc herniations represent a common and debilitating injury to the professional athlete. The NFL's (National Football League's) Sports Injury Monitoring System is a surveillance database created to monitor the league for all injuries, including injuries to the cervical, thoracic, and lumbar spine. A retrospective analysis was performed on all disc herniations to the cervical, thoracic, and lumbar spine during a 12-season period (2000–2012) using the NFL's surveillance database. The primary data points included the location of the injury, player position, activity at time of injury, and playing time lost due to injury. During the 12 seasons, 275 disc herniations occurred in the spine. In regard to location, 76% occurred in the lumbar spine and most frequently affected the L5–S1 disc. The offensive linemen were most frequently injured. As expected, blocking was the activity that caused most injuries. Lumbar disc herniations rose in prevalence and had a mean loss of playing time of more than half the season (11 games). Thoracic disc herniations led to the largest mean number of days lost overall, whereas players with cervical disc herniations missed the most practices. Disc herniations represent a significant cause of morbidity in the NFL. Although much attention is placed on spinal cord injuries, preventive measures targeting the cervical, thoracic, and lumbar spine may help to reduce the overall incidence of these debilitating injuries. N/A
WISE J080822.18-644357.3 - a 45 Myr-old accreting M dwarf hosting a primordial disc
NASA Astrophysics Data System (ADS)
Murphy, Simon J.; Mamajek, Eric E.; Bell, Cameron P. M.
2018-05-01
WISE J080822.18-644357.3 (WISE J0808-6443) was recently identified as a new M dwarf debris disc system and a candidate member of the 45 Myr-old Carina association. Given that the strength of its infrared excess (LIR/L⋆ ≃ 0.1) appears to be more consistent with a young protoplanetary disc, we present the first optical spectra of the star and reassess its evolutionary and membership status. We find WISE J0808-6443 to be a Li-rich M5 star with strong H α emission (-125 < EW < -65 Å over 4 epochs) whose strength and broad width are consistent with accretion at a low level (˜10-10 M⊙ yr-1) from its disc. The spectral energy distribution of the star is consistent with a primordial disc and is well-fitted using a two-temperature blackbody model with Tinner ≃ 1100 K and Touter ≃ 240 K. AllWISE multi-epoch photometry shows the system exhibits significant variability in the 3.4 and 4.6 μm bands. We calculate an improved proper motion based on archival astrometry, and combined with a new radial velocity, the kinematics of the star are consistent with membership in Carina at a kinematic distance of 90 ± 9 pc. The spectroscopic and photometric data are consistent with WISE J0808-6443 being a ˜0.1 M⊙ Classical T-Tauri star and one of the oldest known accreting M-type stars. These results provide further evidence that the upper limit on the lifetimes of gas-rich discs - and hence the time-scales to form and evolve protoplanetary systems - around the lowest mass stars may be longer than previously recognized, or some mechanism may be responsible for regenerating short-lived discs at later stages of pre-main sequence evolution.
LkHα 262/263: the paradigm of multiplicity vs disk fraction in low-mass stellar systems.
NASA Astrophysics Data System (ADS)
Velasco, S.; Rebolo, R.; Oscoz, A.; Labadie, L.; Pérez-Garrido, A.
2017-03-01
The study of multiple systems and their link with the presence of discs around their components is key to understanding the evolution of low-mass pre-main sequence stars. Although there are indications that high-multiplicity systems are much more frequent among very young stars, until now, only a few of these young low-mass stellar systems have been confirmed. Here, we present high spatial resolution i band imaging of the system formed by LkHα 262 and LkHα 263, in the MBM12 cloud. It was obtained during the first commissioning period of the Adaptive Optics Lucky Imager (AOLI) at the 4.2 m William Herschel Telescope, using its Lucky Imaging mode. The multiple system LkHα 262/263 is composed of four low-mass very young M-type stars and some discs, including an edge-on disc around LkHα 263C. The AOLI data combined with previously available and newly obtained optical and infrared imaging show that the three components of LkHα 263 are co-moving, that there is orbital motion in the AB pair (0.41arcsec separation), and, remarkably, that LkHα 262-263 is a common proper motion system with a less than 1 mas/yr relative motion. According to BT-settl models the mass of each of the five components is close to 0.4 M and the age is in the range 1-2 Myr. We also give marginal evidence of a cooler companion to LkHα 262, at less than 0.15 arcsec, turning LkHα 262-263 into a five-component likely gravitationally bounded system. The presence of discs in some of the components offers an interesting opportunity to investigate the formation and evolution of discs in the early stages of multiple very low-mass systems.
Performance, Agility and Cost of Cloud Computing Services for NASA GES DISC Giovanni Application
NASA Astrophysics Data System (ADS)
Pham, L.; Chen, A.; Wharton, S.; Winter, E. L.; Lynnes, C.
2013-12-01
The NASA Goddard Earth Science Data and Information Services Center (GES DISC) is investigating the performance, agility and cost of Cloud computing for GES DISC applications. Giovanni (Geospatial Interactive Online Visualization ANd aNalysis Infrastructure), one of the core applications at the GES DISC for online climate-related Earth science data access, subsetting, analysis, visualization, and downloading, was used to evaluate the feasibility and effort of porting an application to the Amazon Cloud Services platform. The performance and the cost of running Giovanni on the Amazon Cloud were compared to similar parameters for the GES DISC local operational system. A Giovanni Time-Series analysis of aerosol absorption optical depth (388nm) from OMI (Ozone Monitoring Instrument)/Aura was selected for these comparisons. All required data were pre-cached in both the Cloud and local system to avoid data transfer delays. The 3-, 6-, 12-, and 24-month data were used for analysis on the Cloud and local system respectively, and the processing times for the analysis were used to evaluate system performance. To investigate application agility, Giovanni was installed and tested on multiple Cloud platforms. The cost of using a Cloud computing platform mainly consists of: computing, storage, data requests, and data transfer in/out. The Cloud computing cost is calculated based on the hourly rate, and the storage cost is calculated based on the rate of Gigabytes per month. Cost for incoming data transfer is free, and for data transfer out, the cost is based on the rate in Gigabytes. The costs for a local server system consist of buying hardware/software, system maintenance/updating, and operating cost. The results showed that the Cloud platform had a 38% better performance and cost 36% less than the local system. This investigation shows the potential of cloud computing to increase system performance and lower the overall cost of system management.
Badel, Tomislav; Carek, Andreja; Podoreski, Dijana; Pavicin, Ivana Savić; Lovko, Sandra Kocijan
2010-09-01
Temporomandibular disorders are a form of musculoskeletal disorders, which reduce the function of stomatognathic system and they are related to some other diseases causing painful conditions and disorders of oral function. The aim of this paper is to describe a one year follow up clinical case of a female patient with comorbid multiple sclerosis and a relatively rare form of articular disc disorder. Primary clinical diagnostics encompassed manual methods of TMJ examination. Definite diagnosis included radiologic examination. Clinical hyperextensive condyle position was palpated bilaterally and subsequently confirmed by a functional panoramic radiograph of TMJ. The anterior displacement of disc with reduction was diagnosed by magnetic resonance and in the right joint there was a disc displacement upon excursive movement. From relevant literature, the relationship of a number of diseases that can be related to functional disorder of the orofacial system, such as multiple sclerosis, has been described from many aspects. Also, apart from the standard classification of one form of anterior displacement of the disc, made primarily by magnetic resonance, cases of disc displacement upon excursive mandibular movement can rarely be found in literature.
Application of high-speed photography to chip refining
NASA Astrophysics Data System (ADS)
Stationwala, Mustafa I.; Miller, Charles E.; Atack, Douglas; Karnis, A.
1991-04-01
Several high speed photographic methods have been employed to elucidate the mechanistic aspects of producing mechanical pulp in a disc refiner. Material flow patterns of pulp in a refmer were previously recorded by means of a HYCAM camera and continuous lighting system which provided cine pictures at up to 10,000 pps. In the present work an IMACON camera was used to obtain several series of high resolution, high speed photographs, each photograph containing an eight-frame sequence obtained at a framing rate of 100,000 pps. These high-resolution photographs made it possible to identify the nature of the fibrous material trapped on the bars of the stationary disc. Tangential movement of fibre floes, during the passage of bars on the rotating disc over bars on the stationary disc, was also observed on the stator bars. In addition, using a cinestroboscopic technique a large number of high resolution pictures were taken at three different positions of the rotating disc relative to the stationary disc. These pictures were computer analyzed, statistically, to determine the fractional coverage of the bars of the stationary disc with pulp. Information obtained from these studies provides new insights into the mechanism of the refining process.
NASA Astrophysics Data System (ADS)
Bose, Debadin; Chatterjee, Someswar
2016-08-01
Among the various inorganic nanoparticles, silver nanoparticles have received substantial attention in the field of antimicrobial research. For safe and biocompatible use of silver nanoparticles in antimicrobial research, the different biogenic routes are developed to synthesize silver nanoparticles that do not use toxic chemicals. Among those, to synthesize silver nanoparticles, the use of plant part extract becomes an emerging field because plant part acts as reducing as well as capping agent. For large-scale production of antibacterial silver nanoparticles using plant part, the synthesis route should be very simple, rapid, cost-effective and environment friendly based on easy availability and non-toxic nature of plant, stability and antibacterial potential of biosynthesized nanoparticles. In the present study, we report a very simple, rapid, cost-effective and environment friendly route for green synthesis of silver nanoparticles using guava ( Psidium guajava) leaf extract as reducing as well as capping agent. This plant has been opted for the present study for its known medicinal properties, and it is easily available in all seasons and everywhere. The biosynthesized silver nanoparticles are characterized by UV-Vis and TEM analysis. The average particle size is 40 nm in the range of 10-90 nm. The antibacterial activity of these nanoparticles against Pseudomonas aeruginosa MTCC 741 has been measured by disc diffusion method, agar cup assay and serial dilution turbidity measurement assay. The results show that green synthesized silver nanoparticles, using guava ( Psidium guajava) leaf extract, have a potential to inhibit the growth of bacteria.
A Herbivorous Mite Down-Regulates Plant Defence and Produces Web to Exclude Competitors
Sarmento, Renato A.; Lemos, Felipe; Dias, Cleide R.; Kikuchi, Wagner T.; Rodrigues, Jean C. P.; Pallini, Angelo; Sabelis, Maurice W.; Janssen, Arne
2011-01-01
Herbivores may interact with each other through resource competition, but also through their impact on plant defence. We recently found that the spider mite Tetranychus evansi down-regulates plant defences in tomato plants, resulting in higher rates of oviposition and population growth on previously attacked than on unattacked leaves. The danger of such down-regulation is that attacked plants could become a more profitable resource for heterospecific competitors, such as the two-spotted spider mite Tetranychus urticae. Indeed, T. urticae had an almost 2-fold higher rate of oviposition on leaf discs on which T. evansi had fed previously. In contrast, induction of direct plant defences by T. urticae resulted in decreased oviposition by T. evansi. Hence, both herbivores affect each other through induced plant responses. However, when populations of T. evansi and T. urticae competed on the same plants, populations of the latter invariably went extinct, whereas T. evansi was not significantly affected by the presence of its competitor. This suggests that T. evansi can somehow prevent its competitor from benefiting from the down-regulated plant defence, perhaps by covering it with a profuse web. Indeed, we found that T. urticae had difficulties reaching the leaf surface to feed when the leaf was covered with web produced by T. evansi. Furthermore, T. evansi produced more web when exposed to damage or other cues associated with T. urticae. We suggest that the silken web produced by T. evansi serves to prevent competitors from profiting from down-regulated plant defences. PMID:21887311
NASA Astrophysics Data System (ADS)
Grand, Robert
2016-09-01
Simulations are playing an increasingly important role in probing the formation history of the Milky Way, including the formation of the thick/thin disc and origin of the metal distribution and chemo-dynamical relations. We introduce the Auriga project, a suite of high resolution cosmological-zoom simulations of Milky Way-sized galaxies simulated with the state-of-the-art cosmological magneto-hydrodynamical code AREPO, and present an analysis of the formation and evolution of the stellar disc(s) from early times to present day. In particular, we show that 'thickened discs' are mainly driven by a bar (if present) and interactions with satellites of masses log10 (M/ Mo ) >= 10, whereas other potential heating mechanisms such as spiral arms, radial migration, and adiabatic heating from mid-plane density growth are all sub-dominant. Interestingly, we find that even in cases of violent satellite interactions the disc reforms quickly (within a few giga years), producing a well-defined disc-bulge system. In nearly all simulations the overall structure of the disc becomes gradually more radially extended and vertically thinner with time, in support of the inside-out, upside-down formation scenario, and without the presence of a thin/thick disc dichotomy. In addition, we comment on the mass distribution of mono-abundance populations and their relation to the bulge and disc components, which are readily comparable to observations from surveys such as APOGEE and Gaia.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Voss, D.E.; Cohen, S.A.
1979-11-01
A time-of-flight system utilizing a novel mechanical chopper has been developed to measure the energy spectrum of neutral deuterium atoms emitted from a tokamak plasma. The chopper system consists of a motor, a magnetically levitated shaft, and a chopper disc. The 20 g disc is rigidly attached to a 159 g shaft assembly and the set is supported against gravity in vacuum by permanent magnets and a stabilizing servo system. All components are uhv compatible to avoid contamination to the tokamak and to the detector. The 25.4 cm OD, .005 cm thick, 301 stainless steel chopper disc has 24 .025more » cm wide slots photoetched at an 11.4 cm radius. An effective aperture time of .55 ..mu..s is achieved during typical steady state operation at 22,500 rpm with a vacuum pressure of 2 x 10/sup -8/ torr.« less
USDA-ARS?s Scientific Manuscript database
Leaf area index (LAI) and leaf chlorophyll (Chl) content represent key biophysical and biochemical controls on water, energy and carbon exchange processes in the terrestrial biosphere. In combination, LAI and leaf Chl content provide critical information on vegetation density, vitality and photosynt...
Aerodynamic investigations of a disc-wing
NASA Astrophysics Data System (ADS)
Dumitrache, Alexandru; Frunzulica, Florin; Grigorescu, Sorin
2017-01-01
The purpose of this paper is to evaluate the aerodynamic characteristics of a wing-disc, for a civil application in the fire-fighting system. The aerodynamic analysis is performed using a CFD code, named ANSYS Fluent, in the flow speed range up to 25 m/s, at lower and higher angle of attack. The simulation is three-dimensional, using URANS completed by a SST turbulence model. The results are used to examine the flow around the disc with increasing angle of attack and the structure of the wake.
Outer edges of debris discs. How sharp is sharp?
NASA Astrophysics Data System (ADS)
Thébault, P.; Wu, Y.
2008-04-01
Context: Rings or annulus-like features have been observed in most imaged debris discs. Outside the main ring, while some systems (e.g., β Pictoris and AU Mic) exhibit smooth surface brightness profiles (SB) that fall off roughly as ~r-3.5, others (e.g. HR 4796A and HD 139664) display large drops in luminosity at the ring's outer edge and steeper radial luminosity profiles. Aims: We seek to understand this diversity of outer edge profiles under the “natural” collisional evolution of the system, without invoking external agents such as planets or gas. Methods: We use a multi-annulus statistical code to follow the evolution of a collisional population, ranging in size from dust grains to planetesimals and initially confined within a belt (the “birth ring”). The crucial effect of radiation pressure on the dynamics and spatial distribution of the smallest grains is taken into account. We explore the dependence of the resulting disc surface brightness profile on various parameters. Results: The disc typically evolves toward a “standard” steady state, where the radial surface brightness profile smoothly decreases with radius as r-3.5 outside the birth ring. This confirms and extends the semi-analytical study of Strubbe & Chiang (2006, ApJ, 648, 652) and provides a firm basis for interpreting observed discs. Deviations from this typical profile, in the form of a sharp outer edge and a steeper fall-off, occur for two “extreme” cases: 1) when the birth ring is so massive that it becomes radially optically thick for the smallest grains. However, the required disc mass is probably too high here to be realistic; 2) when the dynamical excitation of the dust-producing planetesimals is so low (< e> and < i> ≤ 0.01) that the smallest grains, which otherwise dominate the optical depth of the system, are preferentially depleted. This low-excitation case, although possibly not generic, cannot be ruled out by observations for most systems, . Conclusions: Our “standard” profile provides a satisfactory explanation for a large group of debris discs that show smooth outer edges and SB ∝ r-3.5. Systems with sharper outer edges, barring other confining agents, could still be explained by “natural” collisional evolution if their dynamical excitation is very low. We show that such a dynamically-cold case provides a satisfactory fit to the specific HR4796A ring.
Chemical contamination remote sensing
NASA Technical Reports Server (NTRS)
Carrico, J. P.; Phelps, K. R.; Webb, E. N.; Mackay, R. A.; Murray, E. R.
1986-01-01
A ground mobile laser test bed system was assembled to assess the feasibility of detection of various types of chemical contamination using Differential Scattering (DISC) and Differential Absorption (DIAL) Lidar techniques. Field experiments with the test bed system using chemical simulants were performed. Topographic reflection and range resolved DIAL detection of vapors as well as DISC detection of aerosols and surface contamination were achieved. Review of detection principles, design of the test bed system, and results of the experiments are discussed.
Does warm debris dust stem from asteroid belts?
NASA Astrophysics Data System (ADS)
Geiler, Fabian; Krivov, Alexander V.
2017-06-01
Many debris discs reveal a two-component structure, with a cold outer and a warm inner component. While the former are likely massive analogues of the Kuiper belt, the origin of the latter is still a matter of debate. In this work, we investigate whether the warm dust may be a signature of asteroid belt analogues. In the scenario tested here, the current two-belt architecture stems from an originally extended protoplanetary disc, in which planets have opened a gap separating it into the outer and inner discs which, after the gas dispersal, experience a steady-state collisional decay. This idea is explored with an analytic collisional evolution model for a sample of 225 debris discs from a Spitzer/IRS catalogue that are likely to possess a two-component structure. We find that the vast majority of systems (220 out of 225, or 98 per cent) are compatible with this scenario. For their progenitors, original protoplanetary discs, we find an average surface density slope of -0.93 ± 0.06 and an average initial mass of (3.3^{+0.4}_{-0.3})× 10^{-3} solar masses, both of which are in agreement with the values inferred from submillimetre surveys. However, dust production by short-period comets and - more rarely - inward transport from the outer belts may be viable, and not mutually excluding, alternatives to the asteroid belt scenario. The remaining five discs (2 per cent of the sample: HIP 11486, HIP 23497, HIP 57971, HIP 85790, HIP 89770) harbour inner components that appear inconsistent with dust production in an 'asteroid belt.' Warm dust in these systems must either be replenished from cometary sources or represent an aftermath of a recent rare event, such as a major collision or planetary system instability.
A 1-D model of the nonlinear dynamics of the human lumbar intervertebral disc
NASA Astrophysics Data System (ADS)
Marini, Giacomo; Huber, Gerd; Püschel, Klaus; Ferguson, Stephen J.
2017-01-01
Lumped parameter models of the spine have been developed to investigate its response to whole body vibration. However, these models assume the behaviour of the intervertebral disc to be linear-elastic. Recently, the authors have reported on the nonlinear dynamic behaviour of the human lumbar intervertebral disc. This response was shown to be dependent on the applied preload and amplitude of the stimuli. However, the mechanical properties of a standard linear elastic model are not dependent on the current deformation state of the system. The aim of this study was therefore to develop a model that is able to describe the axial, nonlinear quasi-static response and to predict the nonlinear dynamic characteristics of the disc. The ability to adapt the model to an individual disc's response was a specific focus of the study, with model validation performed against prior experimental data. The influence of the numerical parameters used in the simulations was investigated. The developed model exhibited an axial quasi-static and dynamic response, which agreed well with the corresponding experiments. However, the model needs further improvement to capture additional peculiar characteristics of the system dynamics, such as the change of mean point of oscillation exhibited by the specimens when oscillating in the region of nonlinear resonance. Reference time steps were identified for specific integration scheme. The study has demonstrated that taking into account the nonlinear-elastic behaviour typical of the intervertebral disc results in a predicted system oscillation much closer to the physiological response than that provided by linear-elastic models. For dynamic analysis, the use of standard linear-elastic models should be avoided, or restricted to study cases where the amplitude of the stimuli is relatively small.
The Formation Of Bulges, Discs And Two Component Galaxies In The CANDELS Survey At z<3
NASA Astrophysics Data System (ADS)
Margaleff Bentabol, Berta; Conselice, Christopher; CANDELS Team
2016-09-01
The most massive galaxies in the local Universe can be classified as disk-dominated and spheroid-dominated (i.e. Hubble type). However, it is unclear how and when these dominant structures form and the possible connection between them. To address this issue we have investigated massive galaxies (logM>10) in the CANDELS fields at the epoch of 1
Comets as a possible source of nanodust in the Solar System cloud and in planetary debris discs
NASA Astrophysics Data System (ADS)
Mann, Ingrid
2017-05-01
Comets, comet-like objects and their fragments are the most plausible source for the dust in both the inner heliosphere and planetary debris discs around other stars. The smallest size of dust particles in debris discs is not known and recent observational results suggest that the size distribution of the dust extends down to sizes of a few nanometres or a few tens of nanometres. In the Solar System, electric field measurements from spacecraft observe events that are explained with high-velocity impacts of nanometre-sized dust. In some planetary debris discs an observed mid- to near-infrared emission supposedly results from hot dust located in the vicinity of the star. And the observed emission is characteristic of dust of sizes a few tens of nanometres. Rosetta observations, on the other hand, provide little information on the presence of nanodust near comet 67P/Churyumov-Gerasimenko. This article describes why this is not in contradiction to the observations of nanodust in the heliosphere and in planetary debris discs. The direct ejection of nanodust from the nucleus of the comet would not contribute significantly to the observed nanodust fluxes. We discuss a scenario that nanodust forms in the interplanetary dust cloud through the high-velocity collision process in the interplanetary medium for which the production rates are highest near the Sun. Likewise, fragmentation by collisions occurs near the star in planetary debris discs. The collisional fragmentation process in the inner Solar System occurs at similar velocities to those of the collisional evolution in the interstellar medium. A question for future studies is whether there is a common magic size of the smallest collision fragments and what determines this size. This article is part of the themed issue 'Cometary science after Rosetta'.
Thermal stability of bubble domains in ferromagnetic discs
NASA Astrophysics Data System (ADS)
Hrkac, G.; Bance, S.; Goncharov, A.; Schrefl, T.; Suess, D.
2007-05-01
The transition and thermal stability of disc-shaped ferromagnetic particles at the temperature of T = 300 K with a uniaxial anisotropy along the symmetry axis from a bi-domain to a single domain state has been studied. The nudge elastic band method was used to map the energy landscape and to calculate the energy barrier between the transition states. For single FePt disc-shaped particles with perpendicular anisotropy three transition configurations have been found: single domain, stripe- and stable bubble domains at zero applied field. The single domain configuration along the positive anisotropy axis is reached by an annihilation process of the domain wall and the all-down state by a complex domain expansion process. Magnetization configurations in two interacting discs show an increase in thermal stability compared with single disc systems, which is attributed to the interacting magnetostatic energy between the two particles.
Mishra, Monali P; Padhy, Rabindra N
2013-12-01
To screen methanolic leaf extracts of 21 timber-yielding plants for antibacterial activity against nine species of uropathogenic bacteria isolated from clinical samples of a hospital (Enterococcus faecalis, Staphylococcus aureus, Acinetobacter baumannii, Citrobacter freundii, Enterobacter aerogenes, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Pseudomonas aeruginosa). Bacterial strains were subjected to antibiotic sensitivity tests by the Kirby-Bauer's disc diffusion method. The antibacterial potentiality of leaf extracts was monitored by the agar-well diffusion method with multidrug-resistant (MDR) strains of nine uropathogens. Two Gram-positive isolates, E. faecalis and S. aureus, were resistant to 14 of the 18 antibiotics used. Gram-negative isolates A. baumannii, C. freundii, E. aerogenes, E. coli, K. pneumoniae, P. mirabilis, and P. aeruginosa were resistant to 10, 12, 9, 11, 11, 10, and 11 antibiotics, respectively, of the 14 antibiotics used. Methanolic leaf extracts of Anogeissus acuminata had the maximum zone of inhibition size-29 mm against S. aureus and 28 mm against E. faecalis and P. aeruginosa. Cassia tora had 29 mm as the zone of inhibition size for E. faecalis, E. aerogenes, and P. aeruginosa. Based on the minimum inhibitory concentration and minimum bactericidal concentration values, the most effective 10 plants against uropathogens could be arranged in decreasing order as follows: C. tora > A. acuminata > Schleichera oleosa > Pterocarpus santalinus > Eugenia jambolana > Bridelia retusa > Mimusops elengi > Stereospermum kunthianum > Tectona grandis > Anthocephalus cadamba. The following eight plants had moderate control capacity: Artocarpus heterophyllus, Azadirachta indica, Dalbergia latifolia, Eucalyptus citriodora, Gmelina arborea, Pongamia pinnata, Pterocarpus marsupium, and Shorea robusta. E. coli, followed by A. baumannii, C. freundii, E. aerogenes, P. mirabilis, and P. aeruginosa were controlled by higher amounts/levels of leaf extracts. Phytochemicals of all plants were qualitatively estimated. A majority of timber-yielding plants studied had in vitro control capacity against MDR uropathogenic bacteria.
Bergsträsser, Sergej; Fanourakis, Dimitrios; Schmittgen, Simone; Cendrero-Mateo, Maria Pilar; Jansen, Marcus; Scharr, Hanno; Rascher, Uwe
2015-01-01
Combined assessment of leaf reflectance and transmittance is currently limited to spot (point) measurements. This study introduces a tailor-made hyperspectral absorption-reflectance-transmittance imaging (HyperART) system, yielding a non-invasive determination of both reflectance and transmittance of the whole leaf. We addressed its applicability for analysing plant traits, i.e. assessing Cercospora beticola disease severity or leaf chlorophyll content. To test the accuracy of the obtained data, these were compared with reflectance and transmittance measurements of selected leaves acquired by the point spectroradiometer ASD FieldSpec, equipped with the FluoWat device. The working principle of the HyperART system relies on the upward redirection of transmitted and reflected light (range of 400 to 2500 nm) of a plant sample towards two line scanners. By using both the reflectance and transmittance image, an image of leaf absorption can be calculated. The comparison with the dynamically high-resolution ASD FieldSpec data showed good correlation, underlying the accuracy of the HyperART system. Our experiments showed that variation in both leaf chlorophyll content of four different crop species, due to different fertilization regimes during growth, and fungal symptoms on sugar beet leaves could be accurately estimated and monitored. The use of leaf reflectance and transmittance, as well as their sum (by which the non-absorbed radiation is calculated) obtained by the HyperART system gave considerably improved results in classification of Cercospora leaf spot disease and determination of chlorophyll content. The HyperART system offers the possibility for non-invasive and accurate mapping of leaf transmittance and absorption, significantly expanding the applicability of reflectance, based on mapping spectroscopy, in plant sciences. Therefore, the HyperART system may be readily employed for non-invasive determination of the spatio-temporal dynamics of various plant properties.
A Herschel resolved debris disc around HD 105211
NASA Astrophysics Data System (ADS)
Hengst, S.; Marshall, J. P.; Horner, J.; Marsden, S. C.
2017-07-01
Debris discs are the dusty aftermath of planet formation processes around main-sequence stars. Analysis of these discs is often hampered by the absence of any meaningful constraint on the location and spatial extent of the disc around its host star. Multi-wavelength, resolved imaging ameliorates the degeneracies inherent in the modelling process, making such data indispensable in the interpretation of these systems. The Herschel Space Observatory observed HD 105211 (η Cru, HIP 59072) with its Photodetector Array Camera and Spectrometer (PACS) instrument in three far-infrared wavebands (70, 100 and 160 μm). Here we combine these data with ancillary photometry spanning optical to far-infrared wavelengths in order to determine the extent of the circumstellar disc. The spectral energy distribution and multi-wavelength resolved emission of the disc are simultaneously modelled using a radiative transfer and imaging codes. Analysis of the Herschel/PACS images reveals the presence of extended structure in all three PACS images. From a radiative transfer model we derive a disc extent of 87.0 ± 2.5 au, with an inclination of 70.7 ± 2.2° to the line of sight and a position angle of 30.1 ± 0.5°. Deconvolution of the Herschel images reveals a potential asymmetry but this remains uncertain as a combined radiative transfer and image analysis replicates both the structure and the emission of the disc using a single axisymmetric annulus.
Army Medical Imaging System - ARMIS
1992-08-08
modems , scanners, hard disk drives, dot matrix printers, erasable-optical disc drives, CD-ROM drives, WORM disc drives and tape drives are fully...can use 56K leased lines, TI links, digital data circuits, or public telephone lines. 3. ISDN The Integrated Services Digital Network, ISDN, is a
Lunar-forming impacts: processes and alternatives
Canup, R. M.
2014-01-01
The formation of a protolunar disc by a giant impact with the early Earth is discussed, focusing on two classes of impacts: (i) canonical impacts, in which a Mars-sized impactor produces a planet–disc system whose angular momentum is comparable to that in the current Earth and Moon, and (ii) high-angular-momentum impacts, which produce a system whose angular momentum is approximately a factor of 2 larger than that in the current Earth and Moon. In (i), the disc originates primarily from impactor-derived material and thus is expected to have an initial composition distinct from that of the Earth's mantle. In (ii), a hotter, more compact initial disc is produced with a silicate composition that can be nearly identical to that of the silicate Earth. Both scenarios require subsequent processes for consistency with the current Earth and Moon: disc–planet compositional equilibration in the case of (i), or large-scale angular momentum loss during capture of the newly formed Moon into the evection resonance with the Sun in the case of (ii). PMID:25114302
The origin of the eccentricity of the hot Jupiter in CI Tau
NASA Astrophysics Data System (ADS)
Rosotti, G. P.; Booth, R. A.; Clarke, C. J.; Teyssandier, J.; Facchini, S.; Mustill, A. J.
2017-01-01
Following the recent discovery of the first radial velocity planet in a star still possessing a protoplanetary disc (CI Tau), we examine the origin of the planet's eccentricity (e ˜0.3). We show through long time-scale (105 orbits) simulations that the planetary eccentricity can be pumped by the disc, even when its local surface density is well below the threshold previously derived from short time-scale integrations. We show that the disc may be able to excite the planet's orbital eccentricity in <1 Myr for the system parameters of CI Tau. We also perform two-planet scattering experiments and show that alternatively the observed planet may plausibly have acquired its eccentricity through dynamical scattering of a migrating lower mass planet, which has either been ejected from the system or swallowed by the central star. In the latter case the present location and eccentricity of the observed planet can be recovered if it was previously stalled within the disc's magnetospheric cavity.
NASA Technical Reports Server (NTRS)
Petrenko, M.; Hegde, M.; Bryant, K.; Johnson, J. E.; Ritrivi, A.; Shen, S.; Volmer, B.; Pham, L. B.
2015-01-01
Goddard Earth Sciences Data and Information Services Center (GES DISC) has been providing access to scientific data sets since 1990s. Beginning as one of the first Earth Observing System Data and Information System (EOSDIS) archive centers, GES DISC has evolved to offer a wide range of science-enabling services. With a growing understanding of needs and goals of its science users, GES DISC continues to improve and expand on its broad set of data discovery and access tools, sub-setting services, and visualization tools. Nonetheless, the multitude of the available tools, a partial overlap of functionality, and independent and uncoupled interfaces employed by these tools often leave the end users confused as of what tools or services are the most appropriate for a task at hand. As a result, some the services remain underutilized or largely unknown to the users, significantly reducing the availability of the data and leading to a great loss of scientific productivity. In order to improve the accessibility of GES DISC tools and services, we have designed and implemented UUI, the Unified User Interface. UUI seeks to provide a simple, unified, and intuitive one-stop shop experience for the key services available at GES DISC, including sub-setting (Simple Subset Wizard), granule file search (Mirador), plotting (Giovanni), and other services. In this poster, we will discuss the main lessons, obstacles, and insights encountered while designing the UUI experience. We will also present the architecture and technology behind UUI, including NodeJS, Angular, and Mongo DB, as well as speculate on the future of the tool at GES DISC as well as in a broader context of the Space Science Informatics.
Exoplanet recycling in massive white-dwarf debris discs
NASA Astrophysics Data System (ADS)
Van Lieshout, Rik
2017-06-01
When a star evolves into a white dwarf, the planetary system it hosts can become unstable. Planets in such systems may then be scattered onto star-grazing orbits, leading to their tidal disruption as they pass within the white dwarf’s Roche limit. We study the massive, compact debris discs that may arrise from this process using a combination of analytical estimates and numerical modelling. The discs are gravitationally unstable, resulting in an enhanced effective viscosity due to angular momentum transport associated with self-gravity wakes. For disc masses greater than ~1026 g (corresponding to progenitor objects comparable to the Galilean moons), viscous spreading dominates over Poynting-Robertson drag in the outer parts of the disc. In such massive discs, mass is transported both in- and outwards. When the outward-flowing material spreads beyond the Roche limit, it coagulates into new (minor) planets in a process analogous to the ongoing formation of Saturn’s innermost moonlets. This process recycles a substantial fraction of the original disc mass (tens of percents), with the bulk of the mass locked in a single large body orbitting in a 2:1 mean-motion resonance with the Roche limit. As such, the recycling of a tidally disrupted super-Earth could yield an Earth-mass planet on a 10--20 hr orbit. For white dwarfs with a temperature below 6000-7000 K (corresponding to a cooling age of >1--2 Gyr), this orbit is located in the white dwarf’s habitable zone. The recycling process also creates a string of smaller bodies just outside the Roche limit. These may account for the collection of minor planets postulated to orbit white dwarf WD 1145+017.
Rms-flux relation and fast optical variability simulations of the nova-like system MV Lyr
NASA Astrophysics Data System (ADS)
Dobrotka, A.; Mineshige, S.; Ness, J.-U.
2015-03-01
The stochastic variability (flickering) of the nova-like system (subclass of cataclysmic variable) MV Lyr yields a complicated power density spectrum with four break frequencies. Scaringi et al. analysed high-cadence Kepler data of MV Lyr, taken almost continuously over 600 d, giving the unique opportunity to study multicomponent Power Density Spectra (PDS) over a wide frequency range. We modelled this variability with our statistical model based on disc angular momentum transport via discrete turbulent bodies with an exponential distribution of the dimension scale. Two different models were used, a full disc (developed from the white dwarf to the outer radius of ˜1010 cm) and a radially thin disc (a ring at a distance of ˜1010 cm from the white dwarf) that imitates an outer disc rim. We succeed in explaining the two lowest observed break frequencies assuming typical values for a disc radius of 0.5 and 0.9 times the primary Roche lobe and an α parameter of 0.1-0.4. The highest observed break frequency was also modelled, but with a rather small accretion disc with a radius of 0.3 times the primary Roche lobe and a high α value of 0.9 consistent with previous findings by Scaringi. Furthermore, the simulated light curves exhibit the typical linear rms-flux proportionality linear relation and the typical log-normal flux distribution. As the turbulent process is generating fluctuations in mass accretion that propagate through the disc, this confirms the general knowledge that the typical rms-flux relation is mainly generated by these fluctuations. In general, a higher rms is generated by a larger amount of superposed flares which is compatible with a higher mass accretion rate expressed by a larger flux.
Fresnel field interaction applied to scattering from a vegetation layer
NASA Technical Reports Server (NTRS)
Fung, A. K.; Chen, M. F.; Lee, K. K.
1987-01-01
Models for scattering from a vegetation layer treated as a collection of discrete scatterers usually assume far field interaction among scatterers. In a real vegetation medium such as a deciduous forest or a soybean field it is not always true that each leaf is in the far field of other leaves. This paper examines the additional effect when scatterers are permitted to be in the Fresnel zone of one another. Both disc-shaped and needle-shaped leaves are considered. It is found that in general this causes the backscattering coefficient to be lower for the disk-shaped leaves and may be higher or lower for the needle-shaped leaves depending upon polarization, incidence angle, and frequency than those computed under the assumption of conventional far field interaction.
Yi, Seong; Kim, Keung Nyun; Yang, Moon Sul; Yang, Joong Won; Kim, Hoon; Ha, Yoon; Yoon, Do Heum; Shin, Hyun Chul
2010-07-15
Retrospective study of the difference of heterotopic ossification (HO) occurrence according to 3 different types of prosthesis. This study was designed to investigate the difference of HO occurrence according to different type of prosthesis. HO is defined as formation of the bone outside the skeletal system. Reported HO occurrence rate in cervical artificial disc replacement (ADR) was unexpectedly high and varied. But the influencing factors of HO in cervical ADR have not been elucidated well. The prosthesis-related factors for making difference of HO occurrence were investigated in this study. A total of 170 patients undergoing cervical arthroplasty with the Bryan cervical disc prosthesis (Medtroic Sofamor Danek, Memphis, TN), Mobi-C disc prosthesis (LDR Medical, Troyes, France), and ProDisc-C (Synthes, Inc., West Chester, PA) were included. Cervical lateral radiographs obtained before and after surgery were used to identify HO. Occurrence rate, occurrence-free period, location, and grade of HOs were investigated according to the different prosthesis. Each prosthesis group included patients as follows: Bryan disc, 81 patients; Mobi-C, 61 patients; and ProDisc-C, 28 patients. Overall HO rate was 40.6% (69 of 170 patients). Each HO occurrence rate by prosthesis was as follows: the Bryan disc group, 21.0%; Mobi-C group, 52.5%; and the ProDisc-C group, 71.4%. In the survival analysis, all patients showed 27.1 +/- 3.7 months as the median survival. The Bryan disc group showed statistically longer survival (48.4 +/- 7.4 months) than the other groups. Occurrence of HO is an inevitable postoperative complication after cervical ADR. The occurrence rate of HO was higher than our expectation. Moreover, definite differences in occurrence rate according to the prosthesis type were identified by this study.
Exoplanet recycling in massive white-dwarf debris discs
NASA Astrophysics Data System (ADS)
van Lieshout, R.; Kral, Q.; Charnoz, S.; Wyatt, M. C.; Shannon, A.
2018-05-01
Several tens of white dwarfs are known to host circumstellar discs of dusty debris, thought to arise from the tidal disruption of rocky bodies originating in the star's remnant planetary system. This paper investigates the evolution of such discs if they are very massive, as may be the case if their progenitor was a terrestrial planet, moon, or dwarf planet. Assuming the discs are physically thin and flat, like Saturn's rings, their evolution is governed by Poynting-Robertson drag or viscous spreading, where the disc's effective viscosity is due to self-gravity wakes. For discs with masses ≳ 1026 g, located in the outer parts of the tidal disruption zone, viscous spreading dominates the evolution, and mass is transported both in- and outwards. When outwards-spreading material flows beyond the Roche limit, it coagulates into new (minor) planets in a process analogous to the ongoing formation of moonlets at the outer edge of Saturn's rings. The newly formed bodies migrate outwards by exchanging angular momentum with the disc and coalesce into larger objects through mutual collisions. Eventually, the disc's Roche-limit overflow recycles tens of percent of the original disc mass; most ends up in a single large body near 2:1 mean-motion resonance with the disc's outer edge. Hence, the recycling of a tidally disrupted super-Earth, for example, could yield an Earth-mass planet on a ˜10-h orbit, located in the habitable zone for 2-to-10-Gyr-old white dwarfs. The recycling process also creates a population of smaller bodies just outside the Roche limit, which may explain the minor planets recently postulated to orbit WD 1145+017.
On the Radio Detectability of Circumplanetary Discs
NASA Astrophysics Data System (ADS)
Zhu, Zhaohuan; Andrews, Sean M.; Isella, Andrea
2018-06-01
Discs around young planets, so-called circumplanetary discs (CPDs), are essential for planet growth, satellite formation, and planet detection. We study the millimetre and centimetre emission from accreting CPDs by using the simple α disc model. We find that it is easier to detect CPDs at shorter radio wavelengths (e.g. λ ≲ 1 mm). For example, if the system is 140 pc away from us, deep observations (e.g. 5 hours) at ALMA Band 7 (0.87 mm) are sensitive to as small as 0.03 lunar mass of dust in CPDs. If the CPD is around a Jupiter mass planet 20 AU away from the host star and has a viscosity parameter α ≲ 0.001, ALMA can detect this disc when it accretes faster than 10-10M⊙/yr. ALMA can also detect the "minimum mass sub-nebulae" disc if such a disc exists around a young planet in YSOs. However, to distinguish the embedded compact CPD from the circumstellar disc material, we should observe circumstellar discs with large gaps/cavities using the highest resolution possible. We also calculate the CPD fluxes at VLA bands, and discuss the possibility of detecting radio emission from jets/winds launched in CPDs. Finally we argue that, if the radial drift of dust particles is considered, the drifting timescale for millimetre dust in CPDs can be extremely short. It only takes 102-103 years for CPDs to lose millimetre dust. Thus, for CPDs to be detectable at radio wavelengths, mm-sized dust in CPDs needs to be replenished continuously, or the disc has a significant fraction of micron-sized dust or a high gas surface density so that the particle drifting timescale is long, or the radial drift is prevented by other means (e.g. pressure traps).
A novel collinear optical system with annulus mirrors for holographic disc driver
NASA Astrophysics Data System (ADS)
Wang, Ye
2008-12-01
This paper focus on a novel collinear lens system with annulus mirrors for holographic disc driver, both information beam and reference beam are use same laser beam. The expanded and parallel laser beam, center part of it as the information beam then through Fourier transform lens, the beam around center part as a reference beam. On this axis, the ring reference beam reflected by two annulus shaped mirrors, then became a convergent beam, together with the information beam which through the first Fourier transform lens then produce holographic pattern to be write into the holographic disc behind of them, this lens system with two mirrors made the angle between information beam and reference beam more wide, can improved the multiplex level of holographic storage. Pair of Fourier transform lens with advance performance is designed in this paper.
Formation and survival of Population III stellar systems
NASA Astrophysics Data System (ADS)
Hirano, Shingo; Bromm, Volker
2017-09-01
The initial mass function of the first, Population III (Pop III), stars plays a vital role in shaping galaxy formation and evolution in the early Universe. One key remaining issue is the final fate of secondary protostars formed in the accretion disc, specifically whether they merge or survive. We perform a suite of hydrodynamic simulations of the complex interplay among fragmentation, protostellar accretion and merging inside dark matter minihaloes. Instead of the traditional sink particle method, we employ a stiff equation of state approach, so that we can more robustly ascertain the viscous transport inside the disc. The simulations show inside-out fragmentation because the gas collapses faster in the central region. Fragments migrate on the viscous time-scale, over which angular momentum is lost, enabling them to move towards the disc centre, where merging with the primary protostar can occur. This process depends on the fragmentation scale, such that there is a maximum scale of (1-5) × 104 au, inside which fragments can migrate to the primary protostar. Viscous transport is active until radiative feedback from the primary protostar destroys the accretion disc. The final mass spectrum and multiplicity thus crucially depends on the effect of viscosity in the disc. The entire disc is subjected to efficient viscous transport in the primordial case with viscous parameter α ≤ 1. An important aspect of this question is the survival probability of Pop III binary systems, possible gravitational wave sources to be probed with the Advanced LIGO detectors.
Kinetic Self-Assembly of DNA Tiles and Bricks
2016-08-26
research, and educa- tion. This is achieved by freeze drying cell-free systems into paper and other porous substrates to create materials with the...different toehold switches on paper . Experiments were performed by freeze drying the recombinant PT7 expression system onto paper discs, along with linear...DNA encoding specific switch RNAs. The paper discs were rehy- drated with or without the complementary RNA trigger 24 hr after drying and then
Beaubois, Elisabeth; Girard, Sebastien; Lallechere, Sebastien; Davies, Eric; Paladian, Françoise; Bonnet, Pierre; Ledoigt, Gerard; Vian, Alain
2007-07-01
Exposing all of a wild-type tomato plant to electromagnetic radiation evoked rapid and substantial accumulation of basic leucine-zipper transcription factor (bZIP) mRNA in the terminal leaf (#4) with kinetics very similar to that seen in response to wounding, while in the abscisic acid (ABA) mutant (Sitiens), the response was more rapid, but transient. Submitting just the oldest leaf (#1) of a wild-type plant to irradiation evoked bZIP mRNA accumulation both locally in the exposed leaf and systemically in the unexposed (distant) leaf #4, although systemic accumulation was delayed somewhat. Accumulation of Pin2 mRNA was less than bZIP in both the exposed and distant leaves in wild type, but there was no delay in the systemic response. In Sitiens, bZIP mRNA accumulation was far less than in wild type in both local and distant leaves, while Pin2 mRNA accumulation was stronger in the exposed leaf, but totally prevented in the systemic leaf. In the jasmonic acid (JA) mutant (JL-5) and in wild-type plants treated with the ABA biosynthesis inhibitor, naproxen, responses were similar to those in the ABA mutant, while treatment of the exposed leaf with calcium antagonists totally abolished both local and systemic increases in bZIP transcript accumulation.
2013-01-01
Background Caesalpinia bonducella is an important medicinal plant for its traditional uses against different types of diseases. Therefore, the present study investigated the antimicrobial, antidiarrhoeal, and cytotoxic activities of the methanol extract and ethyl acetate, chloroform, and petroleum ether (pet. ether) fractions of C. bonducella leaves. Methods The antibacterial potentialities of methanol extract and its fractions of C. bonducella leaves were investigated by the disc diffusion method against four gram-positive and five gram-negative bacteria at 300, 500 and 800 μg/disc. Kanamycin (30 μg/disc) was used as the standard drug. Antidiarrhoeal activities of leaf extracts were evaluated at two doses (200 and 400 mg/kg) and compared with loperamide in a castor oil-induced diarrhoeal model in rat. The fractions were subjected to a brine shrimp lethality test to evaluate their cytotoxicity. Results The methanol extract and other three fractions exhibited better activities at higher concentrations. Amongst, the chloroform fraction showed maximum activity at all three concentrations (300, 500, and 800 μg/disc) against almost all bacteria. S. aureus and P. aeruginosa showed better sensitivities to all extracts at all three concentrations excluding the pet. ether fraction. Bacillus megaterium and Klebsiella spp. were two bacteria amongst nine that showed lowest sensitivity to the extracts. Maximum zone of inhibition (25-mm) was obtained by the methanol extract at an 800 μg/disc concentration against S. aureus. In the antidiarrhoeal test, all fractions exhibited dose-dependent actions, which were statistically significant (p < 0.05). Ethyl acetate fraction exerted maximum inhibition (51.11%) against defecation, whereas 57.75% inhibition was obtained for loperamide. Moderate cytotoxicity was found for the methanol extract and its three fractions compared with the standard drug vincristine sulfate in the brine shrimp bioassay. In the present study, the LC50 values of the methanol crude extract and ethyl acetate, chloroform, pet. ether fractions and vincristine sulfate were 223.87, 281.84, 112.2, 199.53, and 12.59 μg/mL, respectively. Therefore, the ethyl acetate fraction showed maximum cytotoxicity, whereas minimum cytotoxicity was observed for the chloroform fraction. Conclusion The present study revealed that the ethyl acetate fraction of the C. bonducella leaves has significant antidiarrhoeal properties. The methanol extract and other three fractions of the C. bonducella leaves possess potent antibacterial activities along with moderate cytotoxicities that may lead to new drug development. PMID:23663985
Billah, Muhammad Mutassim; Islam, Rafikul; Khatun, Hajera; Parvin, Shahnaj; Islam, Ekramul; Islam, Sm Anisul; Mia, Akbar Ali
2013-05-12
Caesalpinia bonducella is an important medicinal plant for its traditional uses against different types of diseases. Therefore, the present study investigated the antimicrobial, antidiarrhoeal, and cytotoxic activities of the methanol extract and ethyl acetate, chloroform, and petroleum ether (pet. ether) fractions of C. bonducella leaves. The antibacterial potentialities of methanol extract and its fractions of C. bonducella leaves were investigated by the disc diffusion method against four gram-positive and five gram-negative bacteria at 300, 500 and 800 μg/disc. Kanamycin (30 μg/disc) was used as the standard drug. Antidiarrhoeal activities of leaf extracts were evaluated at two doses (200 and 400 mg/kg) and compared with loperamide in a castor oil-induced diarrhoeal model in rat. The fractions were subjected to a brine shrimp lethality test to evaluate their cytotoxicity. The methanol extract and other three fractions exhibited better activities at higher concentrations. Amongst, the chloroform fraction showed maximum activity at all three concentrations (300, 500, and 800 μg/disc) against almost all bacteria. S. aureus and P. aeruginosa showed better sensitivities to all extracts at all three concentrations excluding the pet. ether fraction. Bacillus megaterium and Klebsiella spp. were two bacteria amongst nine that showed lowest sensitivity to the extracts. Maximum zone of inhibition (25-mm) was obtained by the methanol extract at an 800 μg/disc concentration against S. aureus. In the antidiarrhoeal test, all fractions exhibited dose-dependent actions, which were statistically significant (p < 0.05). Ethyl acetate fraction exerted maximum inhibition (51.11%) against defecation, whereas 57.75% inhibition was obtained for loperamide. Moderate cytotoxicity was found for the methanol extract and its three fractions compared with the standard drug vincristine sulfate in the brine shrimp bioassay. In the present study, the LC50 values of the methanol crude extract and ethyl acetate, chloroform, pet. ether fractions and vincristine sulfate were 223.87, 281.84, 112.2, 199.53, and 12.59 μg/mL, respectively. Therefore, the ethyl acetate fraction showed maximum cytotoxicity, whereas minimum cytotoxicity was observed for the chloroform fraction. The present study revealed that the ethyl acetate fraction of the C. bonducella leaves has significant antidiarrhoeal properties. The methanol extract and other three fractions of the C. bonducella leaves possess potent antibacterial activities along with moderate cytotoxicities that may lead to new drug development.
The extremely truncated circumstellar disc of V410 X-ray 1: a precursor to TRAPPIST-1?
NASA Astrophysics Data System (ADS)
Boneberg, D. M.; Facchini, S.; Clarke, C. J.; Ilee, J. D.; Booth, R. A.; Bruderer, S.
2018-06-01
Protoplanetary discs around brown dwarfs and very low mass (VLM) stars offer some of the best prospects for forming Earth-sized planets in their habitable zones. To this end, we study the nature of the disc around the VLM star V410 X-ray 1, whose spectral energy distribution (SED) is indicative of an optically thick and very truncated dust disc, with our modelling suggesting an outer radius of only 0.6 au. We investigate two scenarios that could lead to such a truncation, and find that the observed SED is compatible with both. The first scenario involves the truncation of both the dust and gas in the disc, perhaps due to a previous dynamical interaction or the presence of an undetected companion. The second scenario involves the fact that a radial location of 0.6 au is close to the expected location of the H2O snowline in the disc. As such, a combination of efficient dust growth, radial migration, and subsequent fragmentation within the snowline leads to an optically thick inner dust disc and larger, optically thin outer dust disc. We find that a firm measurement of the CO J = 2-1 line flux would enable us to distinguish between these two scenarios, by enabling a measurement of the radial extent of gas in the disc. Many models we consider contain at least several Earth-masses of dust interior to 0.6 au, suggesting that V410 X-ray 1 could be a precursor to a system with tightly packed inner planets, such as TRAPPIST-1.
Gold nanoparticles on titanium and interaction with prototype protein.
Padmos, J Daniel; Duchesne, Paul; Dunbar, Michael; Zhang, Peng
2010-10-01
Modifying titanium (Ti) implant surfaces with functional proteins can strengthen the interface between prosthesis and bone. A prototype system was developed using gold nanoparticles (AuNPs) to immobilize proteins onto Ti. An electroless (galvanic displacement) deposition method was first used to form AuNPs of controlled size and coverage on commercial Ti foil (giving Ti-AuNPs). Parameters were then modified to create two groups of discs (n = 26) with different average AuNP diameters. Scanning electron microscopy and X-ray photoelectron spectroscopy were used to characterize the morphology and surface structure of Ti-AuNPs. To study the interaction of Ti-AuNPs with proteins, Ti discs (n = 8) modified with plain AuNPs and discs (n = 8) modified with thiol (HS--R--COOH)-functionalized AuNPs were treated with lysozyme solution. The amount and activity of the lysozyme on the discs were examined with Micro-BCA and enzymatic assays. Lysozyme was immobilized onto the discs, and the assays showed that the discs with thiol-functionalized AuNPs, discs with bare AuNPs, and Ti controls had average lysozyme adsorptions of 23 x 10(4), 2.3 x 10(4), and 5.7 x 10(4) microg/m2, respectively. The activity assays showed that 21.5, 18.4, and 12.5% of the adsorbed lysozyme was active on the discs with thiol-functionalized AuNPs, discs with bare AuNPs, and Ti controls, respectively. This technique holds promise for binding functional biomolecules to surgical implants, hence possibly creating implant surfaces that react to their local environment. Copyright 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2010.
Chernyakova, M.; Abdo, A. A.; Neronov, A.; ...
2014-01-30
Here, we report on broad multiwavelength observations of the 2010–2011 periastron passage of the γ-ray loud binary system PSR B1259-63. High-resolution interferometric radio observations establish extended radio emission trailing the position of the pulsar. Observations with the FermiGamma-ray Space Telescope reveal GeV γ-ray flaring activity of the system, reaching the spin-down luminosity of the pulsar, around 30 d after periastron. Furthermore, there are no clear signatures of variability at radio, X-ray and TeV energies at the time of the GeV flare. Variability around periastron in the Hα emission line, can be interpreted as the gravitational interaction between the pulsar andmore » the circumstellar disc. The equivalent width of the Hα grows from a few days before periastron until a few days later, and decreases again between 18 and 46 d after periastron. In near-infrared we observe the similar decrease of the equivalent width of Brγ line between the 40th and 117th day after the periastron. For the idealized disc, the variability of the Hα line represents the variability of the mass and size of the disc. Finally, we discuss possible physical relations between the state of the disc and GeV emission under assumption that GeV flare is directly related to the decrease of the disc size.« less
NASA Astrophysics Data System (ADS)
Zakhozhay, Olga V.
2017-04-01
We study a possibility to detect signatures of brown dwarf companions in a circumstellar disc based on spectral energy distributions. We present the results of spectral energy distribution simulations for a system with a 0.8 M⊙ central object and a companion with a mass of 30 M J embedded in a typical protoplanetary disc. We use a solution to the one-dimensional radiative transfer equation to calculate the protoplanetary disc flux density and assume, that the companion moves along a circular orbit and clears a gap. The width of the gap is assumed to be the diameter of the brown dwarf Hill sphere. Our modelling shows that the presence of such a gap can initiate an additional minimum in the spectral energy distribution profile of a protoplanetary disc at λ = 10-100 μm. We found that it is possible to detect signatures of the companion when it is located within 10 AU, even when it is as small as 3 M J. The spectral energy distribution of a protostellar disc with a massive fragment (of relatively cold temperature 400 K) might have a similar double peaked profile to the spectral energy distribution of a more evolved disc that contains a gap.
Sasakawa, Kei; Umegaki, Koji; Sakurai, Shinji
2018-04-01
We aimed to assess the relationship between throwing distance and kinematic release parameters of the flying disc in unskilled throwers, and to assess the relationship between kinetic variables acting on flying discs and the change in spin velocity during long forehand throws by skilled and unskilled throwers. Ten skilled and eleven unskilled throwers performed throws at maximum effort. Reflective marker positions on the disc and body were recorded with a 3D motion capture system during the throws to derive kinematic variables of a disc and kinetic variables acting on the disc. The analysis interval was from maximum external shoulder rotation to disc release. Significant correlations were observed between the throwing distance and spin velocity in skilled (r = 0.722, P < 0.05) and unskilled throwers (r = 0.794, P < 0.01), between the change in spin velocity and the angular impulse of moments of force, in unskilled throwers (r = 0.703, P < 0.05), and between the change in spin velocity and the angular impulse of torque among skilled throwers (r = 0.680, P < 0.01). Therefore, a strategy for increasing spin velocity in unskilled throwers could be used to generate a larger torque, similar to that observed in skilled throwers.
Gas Modelling in the Disc of HD 163296
NASA Technical Reports Server (NTRS)
Tilling, I.; Woitke, P.; Meeus, G.; Mora, A.; Montesinos, B.; Riviere-Marichalar, P.; Eiroa, C.; Thi, W. -F.; Isella, A.; Roberge, A.;
2011-01-01
We present detailed model fits to observations of the disc around the Herbig Ae star HD 163296. This well-studied object has an age of approx. 4Myr, with evidence of a circumstellar disc extending out to approx. 540AU. We use the radiation thermo-chemical disc code ProDiMo to model the gas and dust in the circumstellar disc of HD 163296, and attempt to determine the disc properties by fitting to observational line and continuum data. These include new Herschel/PACS observations obtained as part of the open-time key program GASPS (Gas in Protoplanetary Systems), consisting of a detection of the [Oi] 63 m line and upper limits for several other far infrared lines. We complement this with continuum data and ground-based observations of the CO-12 3-2, 2-1 and CO-13 J=1-0 line transitions, as well as the H2 S(1) transition. We explore the effects of stellar ultraviolet variability and dust settling on the line emission, and on the derived disc properties. Our fitting efforts lead to derived gas/dust ratios in the range 9-100, depending on the assumptions made. We note that the line fluxes are sensitive in general to the degree of dust settling in the disc, with an increase in line flux for settled models. This is most pronounced in lines which are formed in the warm gas in the inner disc, but the low excitation molecular lines are also affected. This has serious implications for attempts to derive the disc gas mass from line observations. We derive fractional PAH abundances between 0.007 and 0.04 relative to ISM levels. Using a stellar and UV excess input spectrum based on a detailed analysis of observations, we find that the all observations are consistent with the previously assumed disc geometry
Truncated disc surface brightness profiles produced by flares
NASA Astrophysics Data System (ADS)
Borlaff, Alejandro; Eliche-Moral, M. Carmen; Beckman, John; Font, Joan
2017-03-01
Previous studies have discarded that flares in galactic discs may explain the truncation that are frequently observed in highly-inclined galaxies (Kregel et al. 2002). However, no study has systematically analysed this hypothesis using realistic models for the disc, the flare and the bulge. We derive edge-on and face-on surface brightness profiles for a series of realistic galaxy models with flared discs that sample a wide range of structural and photometric parameters across the Hubble Sequence, accordingly to observations. The surface brightness profile for each galaxy model has been simulated for edge-on and face-on views to find out whether the flared disc produces a significant truncation in the disc in the edge-on view compared to the face-on view or not. In order to simulate realistic images of disc galaxies, we have considered the observational distribution of the photometric parameters as a function of the morphological type for three mass bins (10 < log10(M/M ⊙) < 10.7, 10.7 < log10(M/M ⊙) < 11 and log10(M/M ⊙) > 11), and four morphological type bins (S0-Sa, Sb-Sbc, Sc-Scd and Sd-Sdm). For each mass bin, we have restricted the photometric and structural parameters of each modelled galaxy to their characteristic observational ranges (μ0, disc, μeff, bulge, B/T, M abs, r eff, n bulge, h R, disc) and the flare in the disc (h z, disc/h R, disc, ∂h z, disc/∂R, see de Grijs & Peletier 1997, Graham 2001, López-Corredoira et al. 2002, Yoachim & Dalcanton 2006, Bizyaev et al. 2014, Mosenkov et al. 2015). Contrary to previous claims, the simulations show that realistic flared disks can be responsible for the truncations observed in many edge-on systems, preserving the profile of the non-flared analogous model in face-on view. These breaks reproduce the properties of the weak-to-intermediate breaks observed in many real Type-II galaxies in the diagram relating the radial location of the break (R brkII) in units of the inner disk scale-length with the break strength S (Laine et al. 2014). Radial variation of the scale-height of the disc (flaring) can explain the existence of many breaks in edge-on galaxies, especially of those with low break strengths 10\\frac{ho}{hi} \\sim \\ [-0.3,-0.1]$ .
NASA Astrophysics Data System (ADS)
Shah, Rajesh C.; Shah, Rajiv B.
2017-12-01
Based on the Shliomis ferrofluid flow model (SFFM) and continuity equation for the film as well as porous region, modified Reynolds equation for lubrication of circular squeeze film bearings is derived by considering the effects of oblique radially variable magnetic field (VMF), slip velocity at the film-porous interface and rotations of both the discs. The squeeze film bearings are made up of circular porous upper disc of different shapes (exponential, secant, mirror image of secant and parallel) and circular impermeable flat lower disc. The validity of Darcy's Law is assumed in the porous region. The SFFM is important because it includes the effects of rotations of the carrier liquid as well as magnetic particles. The VMF is used because of its advantage of generating maximum field at the required active contact area of the bearing design system. Also, the effect of porosity is included because of its advantageous property of self-lubrication. Using Reynolds equation, general form of pressure equation is derived and expression for dimensionless load-carrying capacity is obtained. Using this expression, results for different bearing design systems (due to different shapes of the upper disc) are computed and compared for variation of different parameters.
A novel ethylene responsive factor CitERF13 plays a role in photosynthesis regulation.
Xie, Xiu-Lan; Xia, Xiao-Jian; Kuang, Sheng; Zhang, Xi-Li; Yin, Xue-Ren; Yu, Jing-Quan; Chen, Kun-Song
2017-03-01
Ethylene responsive factors (ERFs) act as critical downstream components of the ethylene signalling pathway in regulating plant development and stress responses. However little is known about its role in regulation of photosynthesis. Here, we identified an ethylene-inducible ERF gene in citrus, CitERF13. Transient over-expression of CitERF13 in N. tabacum leaves, resulted in a significant decrease in net photosynthetic rate. Closer examination of photosynthetic activity of PSII and PSI indicated that CitERF13 overexpression led to declines of F v /F m , Y(II) and Y(I). However, change in NPQ was less pronounced. CitERF13 overexpression also significantly reduced V c,max , J max and AQY, indicating inhibition of the Calvin cycle. The expression of photosynthesis-related genes was suppressed to a variable extent in leaf blades transiently over-expressing CitERF13. CitERF13 transient overexpression in tobacco or citrus both resulted in a decline of Chlorophyll content and CitERF13 overexpressing tobacco leaf disc was more susceptible to chlorosis in response to MV-mediated oxidative stress. The results suggest that CitERF13 is potentially involved in suppressing photosynthesis through multiple pathways, for instance, inhibiting photochemical activity of photosynthesis, CO 2 carboxylation capacity and chlorophyll metabolism. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
Lovtsova, Julia; Gorb, Elena; Dai, Zhendong; Ji, Aihong; Zhao, Zhihui; Jiang, Nan; Gorb, Stanislav N.
2017-01-01
Silks play an important role in the life of various arthropods. A highly neglected prerequisite to make versatile use of silks is sufficient attachment to substrates. Although there have been some studies on the structure and mechanics of silk anchorages of spiders, for insects only anecdotal reports on attachment-associated spinning behaviour exist. Here, we experimentally studied the silk attachment of the pupae and last instar caterpillars of the tea bagworm Eumeta minuscula (Butler 1881) (Lepidoptera, Psychidae) to the leaves of its host plant Ilex chinensis. We found that the bagworms spin attachment discs, which share some structural features with those of spiders, like a plaque consisting of numerous overlaid, looped glue-coated silk fibres and the medially attaching suspension thread. Although the glue, which coats the fibres, cannot spread and adhere very well to the leaf surface, high pull-off forces were measured, yielding a mean safety factor (force divided by the animal weight) of 385.6. Presumably, the bagworms achieve this by removal of the leaf epidermis prior to silk attachment, which exposes the underlying tissue that represents a much better bonding site. This ensures a reliable attachment during the immobile, vulnerable pupal stage. This is the first study on the biomechanics and structure of silk attachments to substrates in insects. PMID:28250101
Pereira, Elvis Almeida; Rocha, Lucas Custódio Lomba; Folly, Henrique; da Silva, Hélio Ricardo; Santana, Diego José
2018-01-01
Based on concordant differences in male advertisement call, tadpole morphology, and absence of haplotype sharing in the barcoding 16S mitochondrial DNA, we describe here a new species of spotted leaf frog of the genus Phasmahyla from Atlantic Forest, State of Rio de Janeiro, Southeast Brazil. The new species is most similar to P. cochranae (type locality) and P. spectabilis (type locality). It differs from these species by the size of the calcar, moderate-sized body (snout-vent length 30.4-34.4 mm in adult eight males), and in the advertisement call. The tadpoles of Phasmahyla lisbella sp. nov. differ from P. exilis , P. spectabilis , P. timbo , P. guttata and P. jandaia because they do not have row of teeth in the anterior part; differ from P. cruzi by the shape of the anterior end of the oral disc. Through genetic data (phylogenetic distance and haplotype genealogy) we diagnosed the new species where the genetic divergences among its congeners is about 3-6% in a fragment of the 16S rRNA gene, which is above the threshold typically characterizing distinct species of anurans. However, the new species can be distinguished from other congeneric species based on an integrative approach (molecular, bioacoustics, larval, and adult morphology).
Roy, Sudipta; Parvin, Rubia; Ghosh, Subhadeep; Bhattacharya, Somesankar; Maity, Santanu; Banerjee, Debdulal
2018-01-01
The tannase production ability by endophytic actinobacteria and the genetic identity of responsible tannase gene were determined. The studied strains were isolated from surface-sterilized leaf discs of Ailanthus excelsa Roxb. Four strains were found to hydrolyze tannic acid on solid media containing 0.4% tannic acid. The strain AL1L was found as tan B LP indicating production of tannase with diverse of substrate affinity. The tannase production from the potential strain AL1L was performed in liquid tannic acid broth (0.4%, w/v). The strain was later identified as Streptomyces sp. AL1L on the basis of 16S rDNA homology. Highest enzyme activity was observed at 48 h of incubation at the exponential growth phase. The enzyme was purified by ammonium sulfate precipitation followed by dialysis (15 kD cut off). This enzyme, with molecular weight 180 kD shows highest catalytic activity at 35 °C, pH 6 with substrate concentration 0.1 g%. The purified enzyme possesses 1.4 × 10 -3 K m and 11.15 U/ml as V max . The above study indicates high industrial prospective of endophytic actinobacteria as source of tannase of potential biotechnological applications.
NASA Technical Reports Server (NTRS)
Tucker, C. J.; Garratt, M. W.
1977-01-01
A stochastic leaf radiation model based upon physical and physiological properties of dicot leaves has been developed. The model accurately predicts the absorbed, reflected, and transmitted radiation of normal incidence as a function of wavelength resulting from the leaf-irradiance interaction over the spectral interval of 0.40-2.50 micron. The leaf optical system has been represented as Markov process with a unique transition matrix at each 0.01-micron increment between 0.40 micron and 2.50 micron. Probabilities are calculated at every wavelength interval from leaf thickness, structure, pigment composition, and water content. Simulation results indicate that this approach gives accurate estimations of actual measured values for dicot leaf absorption, reflection, and transmission as a function of wavelength.
Chang, Chih-Ling; Wang, Ding-Han; Yang, Mu-Chen; Hsu, Wun-Eng; Hsu, Ming-Lun
2018-04-01
Temporomandibular joint (TMJ) is one of the most complex joints of the human body. Due to its unique movement, in terms of combination of rotation and translator movement, disc of the joint plays an important role to maintain its normal function. In order to sustain the normal function of the TMJ, disc must be kept in proper position as well as maintain normal shape in all circumstances. Once the disc is not any more in its normal position during function of the joint, disturbance of the joint can be occurred which will lead to subsequent distortion of the disc. Shape of the disc can be influenced by many factors i.e.: abnormal function or composition of the disc itself. Etiology of the internal derangement of the disc remains controversial. Multifactorial theory has been postulated in most of previous manuscripts. Disc is composed of mainly extracellular matrix. Abnormal proportion of collagen type I & III may also leads to joint hypermobility which may be also a predisposing factor of this disorder. Thus it can be recognized as local manifestation of a systemic disorder. Different treatment modalities with from conservative treatment to surgical intervention distinct success rate have been reported. Recently treatment with extracellular matrix injection becomes more and more popular to strengthen the joint itself. Since multifactorial in character, the best solution of the treatment modalities should be aimed to resolve possible etiology from different aspects. Team work may be indication to reach satisfied results. Copyright © 2018. Published by Elsevier Taiwan.
Basak, Suradeep; Guha, Proshanta
2015-12-23
The current study aimed at characterizing the chemical components of betel leaf (Piper betle L. var. Tamluk Mitha) essential oil (BLEO) and modelling its effect on growth of Penicillium expansum on semi-synthetic medium. Gas chromatography-mass spectrophotometry (GC-MS) analysis of BLEO revealed the presence of different bioactive phenolic compounds in significant amounts. Among 46 different components identified, chavibetol (22.0%), estragole (15.8%), β-cubebene (13.6%), chavicol (11.8%), and caryophyllene (11.3%) were found to be the major compounds of BLEO. A disc diffusion and disc volatilization method were used to evaluate antifungal activity of the oil against a selected food spoilage mould. The logistic model was used to study the kinetics of spore germination. Prediction and validation of antifungal effect of BLEO was performed on semi-synthetic medium (apple juice agar) using predictive microbiological tools. The Baranyi and Roberts model was used to estimate maximum growth rate (μmax in mm/day) and apparent lag time (λ in days) of the mould. Secondary modelling was performed using a re-parameterized Monod-type equation based on cardinal values to study the effect of different BLEO concentration on estimated growth parameters. Emax (minimum concentration of oil at which mould growth was inhibited) and MIC (minimum inhibitory concentration of BLEO at which lag time is infinite) value of BLEO against P. expansum was estimated to be 0.56 and 0.74 μl/ml, respectively, which was found to be similar on potato dextrose agar (PDA) as well as apple juice agar (AJA) medium. The correlation between estimated growth parameters of the mould on both the media was obtained with satisfactory statistical indices (R(2) and RMSE). This study revealed inhibitory efficacy of BLEO on spore germination, mycelial growth and apparent lag time of P. expansum in a dose-dependent manner. Hence, BLEO has potential to be used as a natural food preservative. Copyright © 2015 Elsevier B.V. All rights reserved.
Glial cell migration in the eye disc.
Silies, Marion; Yuva, Yeliz; Engelen, Daniel; Aho, Annukka; Stork, Tobias; Klämbt, Christian
2007-11-28
Any complex nervous system is made out of two major cell types, neurons and glial cells. A hallmark of glial cells is their pronounced ability to migrate. En route to their final destinations, glial cells are generally guided by neuronal signals. Here we show that in the developing visual system of Drosophila glial cell migration is largely controlled by glial-glial interactions and occurs independently of axonal contact. Differentiation into wrapping glia is initiated close to the morphogenetic furrow. Using single cell labeling experiments we identified six distinct glial cell types in the eye disc. The migratory glial population is separated from the wrapping glial cells by the so-called carpet cells, extraordinary large glial cells, each covering a surface area of approximately 10,000 epithelial cells. Subsequent cell ablation experiments demonstrate that the carpet glia regulates glial migration in the eye disc epithelium and suggest a new model underlying glial migration and differentiation in the developing visual system.
Spatially resolved mid-infrared observations of the triple system T Tauri
NASA Astrophysics Data System (ADS)
Ratzka, Th.; Schegerer, A. A.; Leinert, Ch.; Ábrahám, P.; Henning, Th.; Herbst, T. M.; Köhler, R.; Wolf, S.; Zinnecker, H.
2009-08-01
Aims: The aim of this study is to enhance our knowledge of the characteristics and distribution of the circumstellar dust associated with the individual components of the young hierarchical triple system T Tau. Methods: To reach this goal, observations in the N-band (8-13 μm) with the two-telescope interferometric instrument MIDI at the VLTI were performed. For the northern component of the T Tau system, projected baseline lengths of 43 m, 62 m, and 85 m were used. For the southern binary projected baseline lengths of equivalent resolution could be utilised. Our study is based on both the interferometric and the spectrophotometric measurements and is supplemented by new visual and infrared photometry. Also, the phases were investigated to determine the dominating mid-infrared source in the close southern binary. The data were fit with the help of a sophisticated physical disc model. This model utilises the radiative transfer code MC3D that is based on the Monte-Carlo method. Results: Extended mid-infrared emission is found around all three components of the system. Simultaneous fits to the photometric and interferometric data confirm the picture of an almost face-on circumstellar disc around T Tau N. Towards this star, the silicate band is seen in emission. This emission feature is used to model the dust content of the circumstellar disc. Clear signs of dust processing are found. Towards T Tau S, the silicate band is seen in absorption. This absorption is strongly pronounced towards the infrared companion T Tau Sa as can be seen from the first individual N-band spectra for the two southern components. Our fits support the previous suggestion that an almost edge-on disc is present around T Tau Sa. This disc is thus misaligned with respect to the circumstellar disc around T Tau N. The interferometric data indicate that the disc around T Tau Sa is oriented in the north-south direction, which favours this source as launching site for the east-western jet. We further determine from the interferometric data the relative positions of the components of the southern binary in the N-band. We find good agreement with recent position measurements in the near-infrared. Based on observations with the Very Large Telescope Interferometer (VLTI, proposal 074. C-0209(A) and 077.C-0176(C)).
NASA Astrophysics Data System (ADS)
Kempler, S.; Teng, W.; Friedl, L.; Lynnes, C.
2008-12-01
In recognizing the significance of NASA remote sensing Earth science data in monitoring and better understanding our planet's natural environment, NASA has implemented the 'Decision Support Through Earth Science Research Results' program to solicit "proposals that develop and demonstrate innovative and practicable applications of NASA Earth science observations and research"that focus on improving decision making activities", as stated in the NASA ROSES-2008, A.18 solicitation. This very successful program has yielded several monitoring, surveillance, and decision support systems through collaborations with benefiting organizations in the areas of agriculture, air quality, disaster management, ecosystems, public health, water resources, and aviation weather. The Goddard Space Flight Center (GSFC) Earth Sciences Data and Information Services Center (GES DISC) has participated in this program on two projects (one complete, one ongoing), and has had opportune ad hoc collaborations gaining much experience in the formulation, management, development, and implementation of decision support systems utilizing NASA Earth science data. Coupling this experience with the GES DISC's total understanding and vast experience regarding Earth science missions and resulting data and information, including data structures, data usability and interpretation, data interoperability, and information management systems, the GES DISC is in the unique position to more readily identify challenges that come with bringing science data to decision makers. These challenges consist of those that can be met within typical science data usage frameworks, as well as those challenges that arise when utilizing science data for previously unplanned applications, such as decision support systems. The purpose of this presentation is to share GES DISC decision support system project experiences in regards to system sustainability, required data quality (versus timeliness), data provider understanding how decisions are made, which leads to the data receivers willingness to use new types of information to make decisions, as well as other topics. In addition, defining metrics that 'really' evaluate success will be exemplified.
NASA Technical Reports Server (NTRS)
Kempler, Steven; Lynnes, Christopher; Vollmer, Bruce; Alcott, Gary; Berrick, Stephen
2009-01-01
Increasingly sophisticated National Aeronautics and Space Administration (NASA) Earth science missions have driven their associated data and data management systems from providing simple point-to-point archiving and retrieval to performing user-responsive distributed multisensor information extraction. To fully maximize the use of remote-sensor-generated Earth science data, NASA recognized the need for data systems that provide data access and manipulation capabilities responsive to research brought forth by advancing scientific analysis and the need to maximize the use and usability of the data. The decision by NASA to purposely evolve the Earth Observing System Data and Information System (EOSDIS) at the Goddard Space Flight Center (GSFC) Earth Sciences (GES) Data and Information Services Center (DISC) and other information management facilities was timely and appropriate. The GES DISC evolution was focused on replacing the EOSDIS Core System (ECS) by reusing the In-house developed disk-based Simple, Scalable, Script-based Science Product Archive (S4PA) data management system and migrating data to the disk archives. Transition was completed in December 2007
Tarafder, Solaiman; Koch, Alia; Jun, Yena; Chou, Conrad; Awadallah, Mary R; Lee, Chang H
2016-04-25
Three dimensional (3D) printing has emerged as an efficient tool for tissue engineering and regenerative medicine, given its advantages for constructing custom-designed scaffolds with tunable microstructure/physical properties. Here we developed a micro-precise spatiotemporal delivery system embedded in 3D printed scaffolds. PLGA microspheres (μS) were encapsulated with growth factors (GFs) and then embedded inside PCL microfibers that constitute custom-designed 3D scaffolds. Given the substantial difference in the melting points between PLGA and PCL and their low heat conductivity, μS were able to maintain its original structure while protecting GF's bioactivities. Micro-precise spatial control of multiple GFs was achieved by interchanging dispensing cartridges during a single printing process. Spatially controlled delivery of GFs, with a prolonged release, guided formation of multi-tissue interfaces from bone marrow derived mesenchymal stem/progenitor cells (MSCs). To investigate efficacy of the micro-precise delivery system embedded in 3D printed scaffold, temporomandibular joint (TMJ) disc scaffolds were fabricated with micro-precise spatiotemporal delivery of CTGF and TGFβ3, mimicking native-like multiphase fibrocartilage. In vitro, TMJ disc scaffolds spatially embedded with CTGF/TGFβ3-μS resulted in formation of multiphase fibrocartilaginous tissues from MSCs. In vivo, TMJ disc perforation was performed in rabbits, followed by implantation of CTGF/TGFβ3-μS-embedded scaffolds. After 4 wks, CTGF/TGFβ3-μS embedded scaffolds significantly improved healing of the perforated TMJ disc as compared to the degenerated TMJ disc in the control group with scaffold embedded with empty μS. In addition, CTGF/TGFβ3-μS embedded scaffolds significantly prevented arthritic changes on TMJ condyles. In conclusion, our micro-precise spatiotemporal delivery system embedded in 3D printing may serve as an efficient tool to regenerate complex and inhomogeneous tissues.
Hossain, M Amzad; Kabir, M J; Salehuddin, S M; Rahman, S M Mizanur; Das, A K; Singha, Sandip Kumar; Alam, Md Khorshed; Rahman, Atiqur
2010-05-01
The antibacterial potential of essential oils and methanol extracts of sweet basil Ocimum basilicum L. (Lamiaceae) was evaluated for controlling the growth range of food-borne pathogenic bacteria. Essential oils extracted by hydrodistillation from the leaves and stems were analyzed by GC-MS. Fifty-seven compounds representing 94.9 and 96.1% of the total leaf and stem oils, respectively, were identified, of which methyl chavicol (36.7 and 29.9%), gitoxigenin (9.3 and 10.2%), trimethoquinol (10.3 and 8.4%), beta-guaiene (3.7 and 4.1%), aciphyllene (3.4 and 3.0%), alizarin (3.2 and 4.4%), naphthaline (2.2 and 3.8%), (-)-caryophyllene (2.0 and 1.9%), and mequinol (1.6 and 1.8%) were the major compounds. The essential oils (10 microL/disc of 1:5, v/v dilution with methanol) and methanol extracts (300 microg/disc) of O. basilicum displayed a great potential of antibacterial activity against Bacillius cereus, B. subtilis, B. megaterium, Staphylococcus aureus, Listeria monocytogenes, Escherichia coli, Shigella boydii, S. dysenteriae, Vibrio parahaemolyticus, V. mimicus, and Salmonella typhi with their respective zones of inhibition of 11.2-21.1 mm and MIC values of 62.5-500 microg/mL. The results of this study suggest that the natural products derived from O. basilicum may have potential use in the food and/or pharmaceutical industries as antimicrobial agents.
The Role of Plant Water Storage on Water Fluxes within the Coupled Soil-Plant-Atmosphere System
NASA Astrophysics Data System (ADS)
Huang, C. W.; Duman, T.; Parolari, A.; Katul, G. G.
2015-12-01
Plant water storage (PWS) contributes to whole-plant transpiration (up to 50%), especially in large trees and during severe drought conditions. PWS also can impact water-carbon economy as well as the degree of resistance to drought. A 1-D porous media model is employed to accommodate transient water flow through the plant hydraulic system. This model provides a mechanistic representation of biophysical processes constraining water transport, accounting for plant hydraulic architecture and the nonlinear relation between stomatal aperture and leaf water potential when limited by soil water availability. Water transport within the vascular system from the stem base to the leaf-lamina is modeled using Richards's equation, parameterized with the hydraulic properties of the plant tissues. For simplicity, the conducting flow in the radial direction is not considered here and the capacitance at the leaf-lamina is assumed to be independent of leaf water potential. The water mass balance in the leaf lamina sets the upper boundary condition for the flow system, which links the leaf-level transpiration to the leaf water potential. Thus, the leaf-level gas exchange can be impacted by soil water availability through the water potential gradient from the leaf lamina to the soil, and vice versa. The root water uptake is modeled by a multi-layered macroscopic scheme to account for possible hydraulic redistribution (HR) in certain conditions. The main findings from the model calculations are that (1) HR can be diminished by the residual water potential gradient from roots to leaves at night due to aboveground capacitance, tree height, nocturnal transpiration or the combination of the three. The degree of reduction depends on the magnitude of residual water potential gradient; (2) nocturnal refilling to PWS elevates the leaf water potential that subsequently delays the onset of drought stress at the leaf; (3) Lifting water into the PWS instead of HR can be an advantageous strategy for overstory species especially when drought progresses in the presence of competing understory species.
On the timing behaviour of PSR B1259-63 under the propeller torque from a transient accretion disc
NASA Astrophysics Data System (ADS)
Yi, Shu-Xu; Cheng, K. S.
2018-05-01
The γ-ray pulsar binary system PSR B1259-63 flares in GeV after each periastron. The origin of these flares is still under debate. Recently, in 2017, we proposed a mechanism that might explain the GeV flares. In that model, a transient accretion disc is expected to be formed from the matter that was gravity-captured by the neutron star from the main-sequence companion's circumstellar disc. The transient accretion disc exerts a spin-down torque on the neutron star (i.e. the propeller effect), which might be traceable via pulsar timing observations of PSR B1259-63. In this paper, we consider the propeller effect phenomenologically using a parameter χ, which describes the coupling between the disc matter and the neutron star. Comparing the expected timing residuals with recent observations by Shannon et al., we conclude that the angular momentum transfer is very weak (with the coupling parameter χ ≤ 10-4).
ICT and e-Governance: A Conceptual Model of e-DISC
NASA Astrophysics Data System (ADS)
Tejasvee, Sanjay; Sarangdevot, S. S.; Gahlot, Devendra; Gour, Vishal; Sandal, Shruti
2010-11-01
One of the most important objectives of e-governance is, proper distribution and delivery of government information and services to the citizens. By progression in resources of information technology, great opportunities comes to the government for serve information and services to the citizens and public sector in better manner. This paper intends to examine and explore the conceptual model of e-DISC (Effective Deliverance of Information and Services to the Citizens) The purpose of this paper is to gain a better understanding of e-government in India with the concept of e-DISC with ICTs and how to deal with challenges and barriers for successful e-DISC model with accuracy. The obtained results prove that the utilizing and by increasing interest in the new electronic, information, and communication technologies (ICTs) and e-DISC model in recent time, government improved the quality of e-governance and delivery of information and services and acknowledged the awareness of the system is also valuable.
NASA Astrophysics Data System (ADS)
2008-09-01
Astronomers have been able to study planet-forming discs around young Sun-like stars in unsurpassed detail, clearly revealing the motion and distribution of the gas in the inner parts of the disc. This result, which possibly implies the presence of giant planets, was made possible by the combination of a very clever method enabled by ESO's Very Large Telescope. Uncovering the disc ESO PR Photo 27a/08 Planet-forming Disc Planets could be home to other forms of life, so the study of exoplanets ranks very high in contemporary astronomy. More than 300 planets are already known to orbit stars other than the Sun, and these new worlds show an amazing diversity in their characteristics. But astronomers don't just look at systems where planets have already formed - they can also get great insights by studying the discs around young stars where planets may currently be forming. "This is like going 4.6 billion years back in time to watch how the planets of our own Solar System formed," says Klaus Pontoppidan from Caltech, who led the research. Pontoppidan and colleagues have analysed three young analogues of our Sun that are each surrounded by a disc of gas and dust from which planets could form. These three discs are just a few million years old and were known to have gaps or holes in them, indicating regions where the dust has been cleared and the possible presence of young planets. The new results not only confirm that gas is present in the gaps in the dust, but also enable astronomers to measure how the gas is distributed in the disc and how the disc is oriented. In regions where the dust appears to have been cleared out, molecular gas is still highly abundant. This can either mean that the dust has clumped together to form planetary embryos, or that a planet has already formed and is in the process of clearing the gas in the disc. For one of the stars, SR 21, a likely explanation is the presence of a massive giant planet orbiting at less than 3.5 times the distance between the Earth and the Sun, while for the second star, HD 135344B, a possible planet could be orbiting at 10 to 20 times the Earth-Sun distance. The observations of the third star, TW Hydrae, may also require the presence of one or two planets. "Our observations with the CRIRES instrument on ESO's Very Large Telescope clearly reveal that the discs around these three young, Sun-like stars are all very different and will most likely result in very different planetary systems," concludes Pontoppidan. "Nature certainly does not like to repeat herself" [1]. "These kinds of observations complement the future work of the ALMA observatory, which will be imaging these discs in great detail and on a larger scale," adds Ewine van Dishoeck, from Leiden Observatory, who works with Pontoppidan. To study the gaps in dust discs that are the size of the Solar System around stars that are located up to 400 light-years away is a daunting challenge that requires a clever solution and the best possible instruments [2]. "Traditional imaging cannot hope to see details on the scale of planetary distances for objects located so far away," explains van Dishoeck. "Interferometry can do better but won't allow us to follow the motion of the gas." Astronomers used a technique known as 'spectro-astrometric imaging' to give them a window into the inner regions of the discs where Earth-like planets may be forming. They were able not only to measure distances as small as one-tenth the Earth-Sun distance, but to measure the velocity of the gas at the same time [3]. "The particular configuration of the instrument and the use of adaptive optics allows astronomers to carry out observations with this technique in a very user-friendly way: as a consequence, spectro-astrometric imaging with CRIRES can now be routinely performed," says team member Alain Smette, from ESO [4].
NASA Astrophysics Data System (ADS)
Obara, Shin'ya
Plant shoot configurations evolve so that maximum sunlight may be obtained. The objective of this study is to develop a compact light-condensing system mimicking a plant shoot configuration that is applicable to a light source from a large area. In this paper, the relationship between the position of a light source (the sun) and the rate at which light is absorbed by each leaf was investigated in detail for plant shoot models of a dogwood (simple leaf) and a ginkgo tree (lobed leaf). The rate of light quantum received in each leaf model is reported to an analysis program that uses cross entropy (CE). The analyses showed that the peak amount of light received in the plant-shoot-light-condensing system was during February (vernal equinox) and October (autumnal equinox). Similarly, the rate of light quantum received in each leaf was measured with the CE. The results found that the plant-shoot-light-condensing system that maximizes the amount of light received has differences in the light received in each leaf. Furthermore, the light-condensing characteristics of the ginkgo biloba model are better than the dogwood model. The light-condensing characteristics of a leaf are influenced by the size, a lobe, shape, and the length of the branch.
Hu, Zhaoyan; Lu, Lijun; Zhang, Tianyi; Chen, Zhenglong; Zhang, Tao
2013-12-01
This paper mainly studies the driving system of centrifugal blood pump for extracorporeal circulation, with the core being disc magnetic coupling. Structure parameters of disc magnetic coupling are related to the ability of transferring magnetic torque. Therefore, it is necessary to carry out disc magnetic coupling permanent magnet pole number (n), air gap length (L(g)), permanent magnet thickness (L(m)), permanent magnet body inside diameter (R(i)) and outside diameter (R(o)), etc. thoroughly. This paper adopts the three-dimensional static magnetic field edge element method of Ansys for numerical calculation, and analyses the relations of magnetic coupling each parameter to transmission magnetic torque. It provides a good theory basis and calculation method for further optimization of the disc magnetic coupling.
Automated assembly of microfluidic "lab-on-a-disc"
NASA Astrophysics Data System (ADS)
Berger, M.; Müller, T.; Voebel, T.; Baum, C.; Glennon, T.; Mishra, R.; Kinahan, D.; King, D.; Ducrée, J.; Brecher, C.
2018-02-01
Point-of-care (POC) testing attracts more and more attention in the medical health sector because of their specific property to perform the diagnostic close to the patient. The fast diagnosis right at the hospital or the doctor's office improves the medical reaction time and the chances for a successful healing process. One of this POC test systems is a "Lab-on-a-Disc" (LoaD) which looks like a compact disc crisscrossed with microfluidic tubes and cavities. The fluid to be analysed is placed in the LoaD and an external device then rotates the LoaD. The cavities inside the LoaD and the centrifugal force ensure a clearly defined sequence of the analysis. Furthermore, we aim for an inexpensive manufacture of the medical product without neglecting its quality and functionality. Therefore, the Fraunhofer IPT works on an assembly cell to implement dissoluble films concisely into the disc. This dissoluble film demonstrates its successful usage as a gate for the fluid, which opens after a predefined moment in the cycle. Furthermore, we investigate to integrate a laser welding process into our gantry system and demonstrate its efficiency with the welding of polymer discs. This procedure is clinically safe because no further laser absorption material is needed in the sealing process, which might pollute the LoaD. Moreover, this process allows the alignment of several discs before the welding and therefore leads to precisely manufactured LoaDs in large quantities. All these methods together enable a fast, costefficient and reliable mass production to bring POC testing among the people.
TRMM Precipitation Application Examples Using Data Services at NASA GES DISC
NASA Technical Reports Server (NTRS)
Liu, Zhong; Ostrenga, D.; Teng, W.; Kempler, S.; Greene, M.
2012-01-01
Data services to support precipitation applications are important for maximizing the NASA TRMM (Tropical Rainfall Measuring Mission) and the future GPM (Global Precipitation Mission) mission's societal benefits. TRMM Application examples using data services at the NASA GES DISC, including samples from users around the world will be presented in this poster. Precipitation applications often require near-real-time support. The GES DISC provides such support through: 1) Providing near-real-time precipitation products through TOVAS; 2) Maps of current conditions for monitoring precipitation and its anomaly around the world; 3) A user friendly tool (TOVAS) to analyze and visualize near-real-time and historical precipitation products; and 4) The GES DISC Hurricane Portal that provides near-real-time monitoring services for the Atlantic basin. Since the launch of TRMM, the GES DISC has developed data services to support precipitation applications around the world. In addition to the near-real-time services, other services include: 1) User friendly TRMM Online Visualization and Analysis System (TOVAS; URL: http://disc2.nascom.nasa.gov/Giovanni/tovas/); 2) Mirador (http://mirador.gsfc.nasa.gov/), a simplified interface for searching, browsing, and ordering Earth science data at GES DISC. Mirador is designed to be fast and easy to learn; 3) Data via OPeNDAP (http://disc.sci.gsfc.nasa.gov/services/opendap/). The OPeNDAP provides remote access to individual variables within datasets in a form usable by many tools, such as IDV, McIDAS-V, Panoply, Ferret and GrADS; and 4) The Open Geospatial Consortium (OGC) Web Map Service (WMS) (http://disc.sci.gsfc.nasa.gov/services/wxs_ogc.shtml). The WMS is an interface that allows the use of data and enables clients to build customized maps with data coming from a different network.
Review of past, present, and future of recording technology
NASA Astrophysics Data System (ADS)
Al-Jibouri, Abdul-Rahman
2003-03-01
The revolution of information storage and recording has been advanced significantly over the past two decades. Since the development of computers in early 1950s by IBM, the data (information) was stored on magnetic disc by inducing magnetic flux to define the pit direction. The first disc was developed by IBM with diameter of 25inch to store around 10 kByte. After four decades, the disc drive has become more advanced by reducing the drive size, increasing ariel density and cost reduction. The introduction of new computer operating systems and the Internet resulted in the need to develop high ariel density in the 1990s. Therefore, the disc drive manufacturers were pushed harder to develop new technologies at low cost to survive the competitive market. The disc drives, which are based on media (where the data/information is stored) and the head (which will write and read data/information). The head and disc are separated and with the current technology the spacing between the disc and head is about 40nm. A new technology based on magnetic recording was developed to serve the audio market. This technology is called magnetic type, it is similar to the disc drive, but the media is based on tape rather than rigid disc. Another difference being the head and media are in direct contact. Magnetic tape was developed for audio application and a few years later this technology was extended to allow and accept another technology, called video. This allows consumers to record and view movies in their home. The magnetic tape also used the computer industries for back up data. Magnetic tape is still used in computers and has advanced further over the past decade, companies like Quantum Corp has developed digital linear tape.
Evolution of protoplanetary discs with magnetically driven disc winds
NASA Astrophysics Data System (ADS)
Suzuki, Takeru K.; Ogihara, Masahiro; Morbidelli, Alessandro; Crida, Aurélien; Guillot, Tristan
2016-12-01
Aims: We investigate the evolution of protoplanetary discs (PPDs) with magnetically driven disc winds and viscous heating. Methods: We considered an initially massive disc with 0.1 M⊙ to track the evolution from the early stage of PPDs. We solved the time evolution of surface density and temperature by taking into account viscous heating and the loss of mass and angular momentum by the disc winds within the framework of a standard α model for accretion discs. Our model parameters, turbulent viscosity, disc wind mass-loss, and disc wind torque, which were adopted from local magnetohydrodynamical simulations and constrained by the global energetics of the gravitational accretion, largely depends on the physical condition of PPDs, particularly on the evolution of the vertical magnetic flux in weakly ionized PPDs. Results: Although there are still uncertainties concerning the evolution of the vertical magnetic flux that remains, the surface densities show a large variety, depending on the combination of these three parameters, some of which are very different from the surface density expected from the standard accretion. When a PPD is in a wind-driven accretion state with the preserved vertical magnetic field, the radial dependence of the surface density can be positive in the inner region <1-10 au. The mass accretion rates are consistent with observations, even in the very low level of magnetohydrodynamical turbulence. Such a positive radial slope of the surface density strongly affects planet formation because it inhibits the inward drift or even causes the outward drift of pebble- to boulder-sized solid bodies, and it also slows down or even reversed the inward type-I migration of protoplanets. Conclusions: The variety of our calculated PPDs should yield a wide variety of exoplanet systems.
NASA Astrophysics Data System (ADS)
Sobol, Emil; Sviridov, Alexander; Omeltchenko, Alexander; Baum, Olga; Baskov, Andrey; Borchshenko, Igor; Golubev, Vladimir; Baskov, Vladimir
2011-03-01
In 1999 we have introduced a new approach for treatment of spine diseases based on the mechanical effect of nondestructive laser radiation on the nucleus pulposus of the intervertebral disc. Laser reconstruction of spine discs (LRD) involves puncture of the disc and non-destructive laser irradiation of the nucleus pulposus to activate reparative processes in the disc tissues. In vivo animal study has shown that LRD allows activate the growth of hyaline type cartilage in laser affected zone. The paper considers physical processes and mechanisms of laser regeneration, presents results of investigations aimed to optimize laser settings and to develop feedback control system for laser reparation in cartilages of spine and joints. The results of laser reconstruction of intervertebral discs for 510 patients have shown substantial relief of back pain for 90% of patients. Laser technology has been experimentally tested for reparation of traumatic and degenerative diseases in joint cartilage of 20 minipigs. It is shown that laser regeneration of cartilage allows feeling large (more than 5 mm) defects which usually never repair on one's own. Optical techniques have been used to promote safety and efficacy of the laser procedures.
The effects of dynamic loading on the intervertebral disc.
Chan, Samantha C W; Ferguson, Stephen J; Gantenbein-Ritter, Benjamin
2011-11-01
Loading is important to maintain the balance of matrix turnover in the intervertebral disc (IVD). Daily cyclic diurnal assists in the transport of large soluble factors across the IVD and its surrounding circulation and applies direct and indirect stimulus to disc cells. Acute mechanical injury and accumulated overloading, however, could induce disc degeneration. Recently, there is more information available on how cyclic loading, especially axial compression and hydrostatic pressure, affects IVD cell biology. This review summarises recent studies on the response of the IVD and stem cells to applied cyclic compression and hydrostatic pressure. These studies investigate the possible role of loading in the initiation and progression of disc degeneration as well as quantifying a physiological loading condition for the study of disc degeneration biological therapy. Subsequently, a possible physiological/beneficial loading range is proposed. This physiological/beneficial loading could provide insight into how to design loading regimes in specific system for the testing of various biological therapies such as cell therapy, chemical therapy or tissue engineering constructs to achieve a better final outcome. In addition, the parameter space of 'physiological' loading may also be an important factor for the differentiation of stem cells towards most ideally 'discogenic' cells for tissue engineering purpose.
Bayır, Şafak
2016-01-01
With the advances in the computer field, methods and techniques in automatic image processing and analysis provide the opportunity to detect automatically the change and degeneration in retinal images. Localization of the optic disc is extremely important for determining the hard exudate lesions or neovascularization, which is the later phase of diabetic retinopathy, in computer aided eye disease diagnosis systems. Whereas optic disc detection is fairly an easy process in normal retinal images, detecting this region in the retinal image which is diabetic retinopathy disease may be difficult. Sometimes information related to optic disc and hard exudate information may be the same in terms of machine learning. We presented a novel approach for efficient and accurate localization of optic disc in retinal images having noise and other lesions. This approach is comprised of five main steps which are image processing, keypoint extraction, texture analysis, visual dictionary, and classifier techniques. We tested our proposed technique on 3 public datasets and obtained quantitative results. Experimental results show that an average optic disc detection accuracy of 94.38%, 95.00%, and 90.00% is achieved, respectively, on the following public datasets: DIARETDB1, DRIVE, and ROC. PMID:27110272
Biomechanical analysis of a new lumbar interspinous device with optimized topology.
Chen, Chen-Sheng; Shih, Shih-Liang
2018-01-06
Interspinous spacers used stand-alone preserve joint movement but provide little protection for diseased segments of the spine. Used as adjuncts with fusion, interspinous spacers offer rigid stability but may accelerate degeneration on adjacent levels. Our new device is intended to balance the stability and preserves motion provided by the implant. A new interspinous spacer was devised according to the results of topology optimization studies. Four finite element (FE) spine models were created that consisted of an intact spine without an implant, implantation of the novel, the device for intervertebral assisted motion (DIAM system), and the Dynesys system. All models were loaded with moments, and their range of motions (ROMs), peak disc stresses, and facet contact forces were analyzed. The limited motion segment ROMs, shielded disc stresses, and unloaded facet contact forces of the new devices were greater than those of the DIAM and Dynesys system at L3-L4 in almost all directions of movements. The ROMs, disc stresses, and facet contact forces of the new devices at L2-L3 were slightly greater than those in the DIAM system, but much lower than those in the Dynesys system in most directions. This study demonstrated that the new device provided more stability at the instrumented level than the DIAM system did, especially in lateral rotation and the bending direction. The device caused fewer adjacent ROMs, lower disc stresses, and lower facet contact forces than the Dynesys system did. Additionally, this study conducted topology optimization to design the new device and created a smaller implant for minimal invasive surgery.
Nondestructive and Real-time Measurement of Moisture in Plant
NASA Astrophysics Data System (ADS)
Ogawa, Yuichi; Kawase, Kodo; Mizuno, Maya; Yamashita, Masatsugu; Otani, Chiko
We constructed a THz transillumination system for water content monitoring, and we succeeded in measuring the moisture level in plants. Our measurement system uses a widely tunable coherent THz parametric oscillator source. As target we chose for this experiment a leaf of Japanese basil. The time variation of the water content in the leaf was monitored in two situations: a leaf freshly cut which is left to dry out, and the leaf of a water stressed plant. We found by real-time measurements that the water content of a cut leaf does not decrease uniformly in time. Also, the response to water stress is delayed by about 5-10 minutes. Furthermore, we demonstrated a moisture measurement using a transillumination THz imaging system. As target we chose for this experiment a leaf of Hedera helix held between two thin plastic sheets. The change of the moisture distribution is clearly visible. These results show that the method described here can be applied to nondestructive and real-time monitoring of water content in plants.
Ceramic composite protection for turbine disc bursts. [for the A-300 aircraft
NASA Technical Reports Server (NTRS)
Gardner, P. B.
1977-01-01
Ceramic composite turbine disc protection panels for the A300B were developed using armor technology. Analytical predictions for modifying the ballistic projectile armor system were verified by a test program conducted to qualify the rotor containment system. With only a slight change in the areal density of the armor system a more than two-fold increase in kinetic energy protection level was achieved. Thickness of the fiberglass reinforced plastic backing material was increased to achieve an optimum ratio of ceramic thickness to backing thickness for the different ballistic defeat condition.
NASA Astrophysics Data System (ADS)
Kandasamy, Kathiresan; Alikunhi, Nabeel M.; Manickaswami, Gayathridevi; Nabikhan, Asmathunisha; Ayyavu, Gopalakrishnan
2013-02-01
The present work investigated the effect of leaf extract from coastal plant Prosopis chilensis on synthesis of silver nanoparticles using AgNO3 as a substrate and to find their antibacterial potential on pathogenic Vibrio species in the shrimp, Penaeus monodon. The leaf extract could be able to produce silver nanoparticles, as evident by gradual change in colour of the reaction mixture consisted of the extract and 1 mM AgNO3 to dark brown. The silver nanoparticles exhibited 2 θ values corresponding to the presence of silver nanocrystal, as evident by X-ray diffraction spectrum. The peaks corresponding to flavanones and terpenoids were found to be stabilizing agents of the nanoparticles, as revealed by Fourier transform infrared spectroscopy. The size of silver nanoparticles ranged from 5 to 25 nm with an average of 11.3 ± 2.1 nm and was mostly of spherical in shape, as confirmed by transmission electron microscopy. The silver nanoparticles were found to inhibit Vibrio pathogens viz., Vibrio cholerae, V. harveyi, and V. parahaemolyticus and this antibacterial effect was better than that of leaf extract, as proved by disc diffusion assay. The nanoparticles were then tested in the shrimp Penaeus monodon challenged with the four species of Vibrio pathogens for 30 days. The shrimps fed with silver nanoparticles exhibited higher survival, associated with immunomodulation in terms of higher haemocyte counts, phenoloxidase and antibacterial activities of haemolymph of P. monodon which is on par with that of control. Thus, the present study proved the possibility of using silver nanoparticles produced by coastal Prosopis chilensis as antibacterial agent in controlling vibriosis.
DLA Pre-Award Contracting System
1993-05-01
Gulley DPSSO Bldg 33 Standards Cheryl Haines DISC-RMO Bldg 36 Lead Time Jeff Hammer DGSC-P Bldg 32 DPACS WorkloadjersonnedALT Judy Harroson DLA-Z...33 DPACS Functionality Lou JuIg DISC-RM Bldg 36 Resource Data Sandra King DLA-ZSM 3A675 Project Oversight Scotie Knott DGSC-P Bldg 33 Post Award Dave
Modeling the Compact Disc Read System in Lab
ERIC Educational Resources Information Center
Hinaus, Brad; Veum, Mick
2009-01-01
One of the great, engaging aspects of physics is its application to everyday technology. The compact disc player is an example of one such technology that applies fundamental principles from optics in order to efficiently store and quickly retrieve information. We have created a lab in which students use simple optical components to assemble a…
Compact disk error measurements
NASA Technical Reports Server (NTRS)
Howe, D.; Harriman, K.; Tehranchi, B.
1993-01-01
The objectives of this project are as follows: provide hardware and software that will perform simple, real-time, high resolution (single-byte) measurement of the error burst and good data gap statistics seen by a photoCD player read channel when recorded CD write-once discs of variable quality (i.e., condition) are being read; extend the above system to enable measurement of the hard decision (i.e., 1-bit error flags) and soft decision (i.e., 2-bit error flags) decoding information that is produced/used by the Cross Interleaved - Reed - Solomon - Code (CIRC) block decoder employed in the photoCD player read channel; construct a model that uses data obtained via the systems described above to produce meaningful estimates of output error rates (due to both uncorrected ECC words and misdecoded ECC words) when a CD disc having specific (measured) error statistics is read (completion date to be determined); and check the hypothesis that current adaptive CIRC block decoders are optimized for pressed (DAD/ROM) CD discs. If warranted, do a conceptual design of an adaptive CIRC decoder that is optimized for write-once CD discs.
NASA Astrophysics Data System (ADS)
Messina, S.; Monard, B.; Biazzo, K.; Melo, C. H. F.; Frasca, A.
2014-10-01
Context. The early stage of stellar evolution is characterized by a magnetic coupling between a star and its accretion disc, known as a star-disc locking mechanism. The disc-locking prevents the star to spin its rotation up, and its timescale depends on the disc lifetime, which should not be longer than about 10 Myr. Some mechanisms can significantly shorten this lifetime, allowing a few stars to start spinning up much earlier than other stars and increasing the observed rotation period dispersion among coeval stars. Aims: In the present study, we aim to investigate how the properties of the circumstellar environment can shorten the disc lifetime, more specifically the presence of a close stellar companion. Methods: We have identified a few multiple stellar systems, composed of stars with similar masses, which belong to associations with a known age. Since all parameters that are responsible for the rotational evolution, with the exception of environment properties and initial stellar rotation, are similar for all components, we expect that significant differences among the rotation periods can only arise from differences in the disc lifetimes. A photometric timeseries allowed us to measure the rotation periods of each component, while high-resolution spectra provided us with the fundamental parameters, v sin i and chromospheric line fluxes. Results: In the present study, we have collected timeseries photometry of BD-21 1074, a member of the 21 Myr old β Pictoris association, and measured the rotation periods of its brightest components A and B. They differ significantly, and the component B, which has a closer companion C, rotates faster than the more distant and isolated component A. It also displays a slightly higher chromospheric activity level. Conclusions: Since components A and B have similar mass, age, and initial chemical composition, we can ascribe the rotation period difference to either different initial rotation periods or different disc-locking phases arising from the presence of the close companion C. In the specific case of BD-21 1074, the second scenario seems to be more favored. However, a statistically meaningful sample is yet needed to be able to infer which scenario is more likely. In our hypothesis of different disc-locking phase, any planet orbiting this star, if found by future investigations, is likely formed very rapidly owing to a gravitational instability mechanism, rather than core accretion. Only a large difference of initial rotation periods alone could account for the observed period difference, leaving comparable disc lifetimes.
Hysteresis and thermal limit cycles in MRI simulations of accretion discs
NASA Astrophysics Data System (ADS)
Latter, H. N.; Papaloizou, J. C. B.
2012-10-01
The recurrentoutbursts that characterize low-mass binary systems reflect thermal state changes in their associated accretion discs. The observed outbursts are connected to the strong variation in disc opacity as hydrogen ionizes near 5000 K. This physics leads to accretion disc models that exhibit bistability and thermal limit cycles, whereby the disc jumps between a family of cool and low-accreting states and a family of hot and efficiently accreting states. Previous models have parametrized the disc turbulence via an alpha (or 'eddy') viscosity. In this paper we treat the turbulence more realistically via a suite of numerical simulations of the magnetorotational instability (MRI) in local geometry. Radiative cooling is included via a simple but physically motivated prescription. We show the existence of bistable equilibria and thus the prospect of thermal limit cycles, and in so doing demonstrate that MRI-induced turbulence is compatible with the classical theory. Our simulations also show that the turbulent stress and pressure perturbations are only weakly dependent on each other on orbital times; as a consequence, thermal instability connected to variations in turbulent heating (as opposed to radiative cooling) is unlikely to operate, in agreement with previous numerical results. Our work presents a first step towards unifying simulations of full magnetohydrodynamic turbulence with the correct thermal and radiative physics of the outbursting discs associated with dwarf novae, low-mass X-ray binaries and possibly young stellar objects.
Topographical analysis of corneal astigmatism in patients with tilted-disc syndrome.
Bozkurt, Banu; Irkec, Murat; Gedik, Sansal; Orhan, Mehmet; Erdener, Uğur
2002-07-01
To evaluate the corneal topography in patients with tilted-disc syndrome to determine the relationship between optic disc dysversion and corneal astigmatism and the pattern of astigmatism in these patients. The study included 23 eyes of the 13 tilted-disc syndrome patients with spheric refractive errors ranging between +1.00 D and -9.00 D (mean -4.00 +/- 3.4 D) and astigmatic errors ranging between -0.50 and -4.50 D (mean -1.95 +/- 0.93 D). Corneal topography was performed by computer-assisted videokeratoscope topographic modelling system 2 (TMS-2) and incidence of corneal astigmatism, corneal topographic patterns, and mean values of the topographic indices were determined. Corneal topographic analysis showed corneal astigmatism in 22 out of 23 patients with tilted discs. Corneal astigmatism was symmetric bow tie pattern in 10 eyes (45.45%), asymmetric bow tie pattern in 11 eyes (50%) and irregular in 1 eye (4.5%). Among the patients with bow tie pattern group (21 eyes), 14 eyes had with-the-rule astigmatism, 1 eye had against-the-rule astigmatism, and 6 eyes had oblique astigmatism. In 18 eyes, astigmatism was corneal, whereas combined corneal and lenticular in 4 eyes and lenticular in 1 eye. In the majority of tilted-disc cases, ocular astigmatism is mainly corneal. Morphogenetic factors in the development of the tilted disc might possibly influence the corneal development in such a way to result in corneal astigmatism.
Simulating a slow bar in the low surface brightness galaxy UGC 628
NASA Astrophysics Data System (ADS)
Chequers, Matthew H.; Spekkens, Kristine; Widrow, Lawrence M.; Gilhuly, Colleen
2016-12-01
We present a disc-halo N-body model of the low surface brightness galaxy UGC 628, one of the few systems that harbours a `slow' bar with a ratio of corotation radius to bar length of R ≡ R_c/a_b ˜ 2. We select our initial conditions using SDSS DR10 photometry, a physically motivated radially variable mass-to-light ratio profile, and rotation curve data from the literature. A global bar instability grows in our submaximal disc model, and the disc morphology and dynamics agree broadly with the photometry and kinematics of UGC 628 at times between peak bar strength and the onset of buckling. Prior to bar formation, the disc and halo contribute roughly equally to the potential in the galaxy's inner region, giving the disc enough self-gravity for bar modes to grow. After bar formation, there is significant mass redistribution, creating a baryon-dominated inner and dark matter-dominated outer disc. This implies that, unlike most other low surface brightness galaxies, UGC 628 is not dark matter dominated everywhere. Our model nonetheless implies that UGC 628 falls on the same relationship between dark matter fraction and rotation velocity found for high surface brightness galaxies, and lends credence to the argument that the disc mass fraction measured at the location where its contribution to the potential peaks is not a reliable indicator of its dynamical importance at all radii.
Three-dimensional disc-satellite interaction: torques, migration, and observational signatures
NASA Astrophysics Data System (ADS)
Arzamasskiy, Lev; Zhu, Zhaohuan; Stone, James M.
2018-04-01
The interaction of a satellite with a gaseous disc results in the excitation of spiral density waves, which remove angular momentum from the orbit. In addition, if the orbit is not coplanar with the disc, three-dimensional effects will excite bending and eccentricity waves. We perform three-dimensional hydrodynamic simulations to study nonlinear disc-satellite interaction in inviscid protoplanetary discs for a variety of orbital inclinations from 0° to 180°. It is well known that three-dimensional effects are important even for zero inclination. In this work, we (1) show that for planets with small inclinations (as in the Solar system), effects such as the total torque and migration rate strongly depend on the inclination and are significantly different (about 2.5 times smaller) from the two-dimensional case, (2) give formulae for the migration rate, inclination damping, and precession rate of planets with different inclination angles in disc with different scale heights, and (3) present the observational signatures of a planet on an inclined orbit with respect to the protoplanetary disc. For misaligned planets, we find good agreement with linear theory in the limit of small inclinations, and with dynamical friction estimates for intermediate inclinations. We find that in the latter case, the dynamical friction force is not parallel to the relative planetary velocity. Overall, the derived formulae will be important for studying exoplanets with obliquity.
The co-existence of hot and cold gas in debris discs
NASA Astrophysics Data System (ADS)
Rebollido, I.; Eiroa, C.; Montesinos, B.; Maldonado, J.; Villaver, E.; Absil, O.; Bayo, A.; Canovas, H.; Carmona, A.; Chen, Ch.; Ertel, S.; Garufi, A.; Henning, Th.; Iglesias, D. P.; Launhardt, R.; Liseau, R.; Meeus, G.; Moór, A.; Mora, A.; Olofsson, J.; Rauw, G.; Riviere-Marichalar, P.
2018-06-01
Context. Debris discs have often been described as gas-poor discs as the gas-to-dust ratio is expected to be considerably lower than in primordial, protoplanetary discs. However, recent observations have confirmed the presence of a non-negligible amount of cold gas in the circumstellar (CS) debris discs around young main-sequence stars. This cold gas has been suggested to be related to the outgassing of planetesimals and cometary-like objects. Aims: The goal of this paper is to investigate the presence of hot gas in the immediate surroundings of the cold-gas-bearing debris-disc central stars. Methods: High-resolution optical spectra of all currently known cold-gas-bearing debris-disc systems, with the exception of β Pic and Fomalhaut, have been obtained from La Palma (Spain), La Silla (Chile), and La Luz (Mexico) observatories. To verify the presence of hot gas around the sample of stars, we have analysed the Ca II H&K and the Na I D lines searching for non-photospheric absorptions of CS origin, usually attributed to cometary-like activity. Results: Narrow, stable Ca II and/or Na I absorption features have been detected superimposed to the photospheric lines in 10 out of the 15 observed cold-gas-bearing debris-disc stars. Features are found at the radial velocity of the stars, or slightly blue- or red-shifted, and/or at the velocity of the local interstellar medium (ISM). Some stars also present transient variable events or absorptions extended towards red wavelengths (red wings). These are the first detections of such Ca II features in 7 out of the 15 observed stars. Although an ISM origin cannot categorically be excluded, the results suggest that the stable and variable absorptions arise from relatively hot gas located in the CS close-in environment of the stars. This hot gas is detected in at least 80%, of edge-on cold-gas-bearing debris discs, while in only 10% of the discs seen close to face-on. We interpret this result as a geometrical effect, and suggest that the non-detection of hot gas absorptions in some face-on systems is due to the disc inclination and likely not to the absence of the hot-gas component. This gas is likely released in physical processes related in some way to the evaporation of exocomets, evaporation of dust grains, or grain-grain collisions close to the central star. The reduced spectra are only available at the CDS (ascii files) and at the FEROS archive (FITS files) via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/614/A3
NASA Technical Reports Server (NTRS)
Vollmer, Bruce; Kempler, Steven J.; Ramapriyan, Hampapuram K.
2009-01-01
A major need stated by the NASA Earth science research strategy is to develop long-term, consistent, and calibrated data and products that are valid across multiple missions and satellite sensors. (NASA Solicitation for Making Earth System data records for Use in Research Environments (MEaSUREs) 2006-2010) Selected projects create long term records of a given parameter, called Earth Science Data Records (ESDRs), based on mature algorithms that bring together continuous multi-sensor data. ESDRs, associated algorithms, vetted by the appropriate community, are archived at a NASA affiliated data center for archive, stewardship, and distribution. See http://measures-projects.gsfc.nasa.gov/ for more details. This presentation describes the NASA GSFC Earth Science Data and Information Services Center (GES DISC) approach to managing the MEaSUREs ESDR datasets assigned to GES DISC. (Energy/water cycle related and atmospheric composition ESDRs) GES DISC will utilize its experience to integrate existing and proven reusable data management components to accommodate the new ESDRs. Components include a data archive system (S4PA), a data discovery and access system (Mirador), and various web services for data access. In addition, if determined to be useful to the user community, the Giovanni data exploration tool will be made available to ESDRs. The GES DISC data integration methodology to be used for the MEaSUREs datasets is presented. The goals of this presentation are to share an approach to ESDR integration, and initiate discussions amongst the data centers, data managers and data providers for the purpose of gaining efficiencies in data management for MEaSUREs projects.
Arayasantiparb, Raweewan; Tsuchimochi, Makoto
2010-02-01
Many measures have been developed to determine the extent of disc displacement in internal derangements of the temporomandibular joint (TMJ) using magnetic resonance imaging. The purpose of this study was to develop a quantitative method of analyzing disc position and to evaluate the positions of the disc in internal derangements of the TMJ (group 1, with reduction; group 2, without reduction). Magnetic resonance images of 150 TMJs in 20 healthy volunteers and 55 patients with internal derangements were evaluated. The anatomical points of interest of the TMJ, including the anterior (DA) and posterior (DP) points of the disc, were marked on parasagittal magnetic resonance images of the TMJ disc taken in both the closed- and the open-mouth positions. All points were recorded using an x-y coordinate system, with reference to a referral line. In the closed-mouth position, the DP in patients in group 1 was situated in a more-anterior direction than the DP in volunteers. The DP in group 2 was located further anterior and inferior than the DP in group 1. However, the position of the DA did not differ between group 1 and group 2. In the open-mouth position, the DP was displaced anteroinferiorly to a greater extent in group 2 than in group 1 (one-way ANOVA, followed by Scheffe's test; P < 0.0001). The distance between the disc points in the closed- and open-mouth positions was also evaluated. Comparison of the disc point position in the closed- and open-mouth positions in symptomatic and asymptomatic displaced TMJ discs revealed no significant difference. In conclusion, most of our results quantitatively support previously reported findings in imaging, surgical, and histopathological studies of TMJ internal derangement. We suggest that our measure of disc position of the TMJ would be useful to assess the status and response to treatment of internal derangements of the TMJ.
Comets as a possible source of nanodust in the Solar System cloud and in planetary debris discs.
Mann, Ingrid
2017-07-13
Comets, comet-like objects and their fragments are the most plausible source for the dust in both the inner heliosphere and planetary debris discs around other stars. The smallest size of dust particles in debris discs is not known and recent observational results suggest that the size distribution of the dust extends down to sizes of a few nanometres or a few tens of nanometres. In the Solar System, electric field measurements from spacecraft observe events that are explained with high-velocity impacts of nanometre-sized dust. In some planetary debris discs an observed mid- to near-infrared emission supposedly results from hot dust located in the vicinity of the star. And the observed emission is characteristic of dust of sizes a few tens of nanometres. Rosetta observations, on the other hand, provide little information on the presence of nanodust near comet 67P/Churyumov-Gerasimenko. This article describes why this is not in contradiction to the observations of nanodust in the heliosphere and in planetary debris discs. The direct ejection of nanodust from the nucleus of the comet would not contribute significantly to the observed nanodust fluxes. We discuss a scenario that nanodust forms in the interplanetary dust cloud through the high-velocity collision process in the interplanetary medium for which the production rates are highest near the Sun. Likewise, fragmentation by collisions occurs near the star in planetary debris discs. The collisional fragmentation process in the inner Solar System occurs at similar velocities to those of the collisional evolution in the interstellar medium. A question for future studies is whether there is a common magic size of the smallest collision fragments and what determines this size.This article is part of the themed issue 'Cometary science after Rosetta'. © 2017 The Author(s).
NASA Astrophysics Data System (ADS)
Blajer, W.; Dziewiecki, K.; Kołodziejczyk, K.; Mazur, Z.
2011-05-01
Underactuated systems are featured by fewer control inputs than the degrees-of-freedom, m < n. The determination of an input control strategy that forces such a system to complete a set of m specified motion tasks is a challenging task, and the explicit solution existence is conditioned to differential flatness of the problem. The flatness-based solution denotes that all the 2 n states and m control inputs can be algebraically expressed in terms of the m specified outputs and their time derivatives up to a certain order, which is in practice attainable only for simple systems. In this contribution the problem is posed in a more practical way as a set of index-three differential-algebraic equations, and the solution is obtained numerically. The formulation is then illustrated by a two-degree-of-freedom underactuated system composed of two rotating discs connected by a torsional spring, in which the pre-specified motion of one of the discs is actuated by the torque applied to the other disc, n = 2 and m = 1. Experimental verification of the inverse simulation control methodology is reported.
Concentric Coplanar Capacitive Sensor System with Quantitative Model
NASA Technical Reports Server (NTRS)
Chen, Tianming (Inventor); Bowler, Nicola (Inventor)
2014-01-01
A concentric coplanar capacitive sensor includes a charged central disc forming a first electrode, an outer annular ring coplanar with and outer to the charged central disc, the outer annular ring forming a second electrode, and a gap between the charged central disc and the outer annular ring. The first electrode and the second electrode may be attached to an insulative film. A method provides for determining transcapacitance between the first electrode and the second electrode and using the transcapacitance in a model that accounts for a dielectric test piece to determine inversely the properties of the dielectric test piece.
NASA Astrophysics Data System (ADS)
Khan, Aamir; Shah, Rehan Ali; Shuaib, Muhammad; Ali, Amjad
2018-06-01
The effects of magnetic field dependent (MFD) thermosolutal convection and MFD viscosity of the fluid dynamics are investigated between squeezing discs rotating with different velocities. The unsteady constitutive expressions of mass conservation, modified Navier-Stokes, Maxwell and MFD thermosolutal convection are coupled as a system of ordinary differential equations. The corresponding solutions for the transformed radial and azimuthal momentum as well as solutions for the azimuthal and axial induced magnetic field equations are determined, also the MHD pressure and torque which the fluid exerts on the upper disc is derived and discussed in details. In the case of smooth discs the self-similar equations are solved using Homotopy Analysis Method (HAM) with appropriate initial guesses and auxiliary parameters to produce an algorithm with an accelerated and assured convergence. The validity and accuracy of HAM results is proved by comparison of the HAM solutions with numerical solver package BVP4c. It has been shown that magnetic Reynolds number causes to decrease magnetic field distributions, fluid temperature, axial and tangential velocity. Also azimuthal and axial components of magnetic field have opposite behavior with increase in MFD viscosity. Applications of the study include automotive magneto-rheological shock absorbers, novel aircraft landing gear systems, heating up or cooling processes, biological sensor systems and biological prosthetic etc.
Chai, Yuzhu; Yamamoto, Shuichi; Hirayama, Atsuko; Yotsukura, Jiro; Yamazaki, Hiroko
2005-01-01
To evaluate optic nerve function by pattern visual evoked potentials (VEPs) in eyes with optic disc swelling due to neuroretinitis associated with cat scratch disease (CSD). Four eyes of four patients with marked optic disc swelling resembling optic neuritis but diagnosed serologically as CSD received systemic steroid treatment. VEPs elicited by black and white checkerboard stimuli created on a TV monitor were recorded before the treatment. The visual acuity (VA) in the affected eyes was decreased to 20/50 in two eyes and finger counting in two eyes at their initial visits. Ophthalmoscopic examination revealed neuroretinitis characterized by severe optic disc swelling, chorioretinal exudates, and macular edema in all eyes. Anti-Bartonella henselae serum antibody was markedly elevated in all patients confirming the diagnosis of CSD. The P100 of the transient VEPs was only mildly reduced without a delay in the implicit times in three eyes and only slightly delayed in the other eye. The steady-state VEPs were mildly reduced in two eyes and phase-reversed in other two eyes. The VA fully recovered after systemic steroid treatment in all patients. Although all examined patients showed marked swelling of the optic disc and visual decrease, the pattern VEPs were not affected as severely as in idiopathic optic neuritis. However, the degree of change of the pattern VEPs varied among patients.
Foltz, Mary H; Kage, Craig C; Johnson, Casey P; Ellingson, Arin M
2017-11-01
Intervertebral disc degeneration is a prevalent phenomenon associated with back pain. It is of critical clinical interest to discriminate disc health and identify early stages of degeneration. Traditional clinical T2-weighted magnetic resonance imaging (MRI), assessed using the Pfirrmann classification system, is subjective and fails to adequately capture initial degenerative changes. Emerging quantitative MRI techniques offer a solution. Specifically, T2* mapping images water mobility in the macromolecular network, and our preliminary ex vivo work shows high predictability of the disc's glycosaminoglycan content (s-GAG) and residual mechanics. The present study expands upon this work to predict the biochemical and biomechanical properties in vivo and assess their relationship with both age and Pfirrmann grade. Eleven asymptomatic subjects (range: 18-62 yrs) were enrolled and imaged using a 3T MRI scanner. T2-weighted images (Pfirrmann grade) and quantitative T2* maps (predict s-GAG and residual stress) were acquired. Surface maps based on the distribution of these properties were generated and integrated to quantify the surface volume. Correlational analyses were conducted to establish the relationship between each metric of disc health derived from the quantitative T2* maps with both age and Pfirrmann grade, where an inverse trend was observed. Furthermore, the nucleus pulposus (NP) signal in conjunction with volumetric surface maps provided the ability to discern differences during initial stages of disc degeneration. This study highlights the ability of T2* mapping to noninvasively assess the s-GAG content, residual stress, and distributions throughout the entire disc, which may provide a powerful diagnostic tool for disc health assessment.
Benbelaïd, R; Fleiter, B
2006-03-01
The aim of this study was to evaluate sensitivity and specificity of a new method to locate temporo-mandibular joint (TMJ) disc using magnetic resonance imaging (MRI) and analyze disc-condyle relationships, in asymptomatic subjects and patients with disc displacement. Twenty-nine sagittal MRI of 16 subjects, 8 asymptomatic volunteers and 8 subjects with anterior disc displacement, were carried out during controlled opening from intercuspal position up to a 25 mm opening. Selected sections were analyzed with a graphic computerized system of coordinates. The total surface area (TS) of disc section was separated into anterior surface area (AS) and posterior surface area. Areas were determined by computer. Two trained examiners drew images at random. The reliability of AS/TS ratio index was evaluated in a previous study. AS/TS ratio sensitivity (Se) and specificity (Sp) were calculated closed mouth, 5 mm open and 25 mm open mouth. Best sensitivity (Se=0.63) and specificity (Sp=0.81) were obtained when MRI was realized with closed mouth and 25 mm open mouth. Lower sensitivity was observed when MRI was performed either with closed mouth (Se=0.54) or 25 mm open mouth (Se=0.18). Lower specificity was observed with 5 mm open mouth (Sp=0.68). In conclusion, it was confirmed as well that MRI of anterior disc displacement should be performed with closed mouth and opened mouth. Thus, further studies are required to assess disc displacement and mechanical alterations and to evaluate the risk of direct damage on TMJ tissues.
Leaf shape: genetic controls and environmental factors.
Tsukaya, Hirokazu
2005-01-01
In recent years, many genes have been identified that are involved in the developmental processes of leaf morphogenesis. Here, I review the mechanisms of leaf shape control in a model plant, Arabidopsis thaliana, focusing on genes that fulfill special roles in leaf development. The lateral, two-dimensional expansion of leaf blades is highly dependent on the determination of the dorsoventrality of the primordia, a defining characteristic of leaves. Having a determinate fate is also a characteristic feature of leaves and is controlled by many factors. Lateral expansion is not only controlled by general regulators of cell cycling, but also by the multi-level regulation of meristematic activities, e.g., specific control of cell proliferation in the leaf-length direction, in leaf margins and in parenchymatous cells. In collaboration with the polarized control of leaf cell elongation, these redundant and specialized regulating systems for cell cycling in leaf lamina may realize the elegantly smooth, flat structure of leaves. The unified, flat shape of leaves is also dependent on the fine integration of cell proliferation and cell enlargement. Interestingly, while a decrease in the number of cells in leaf primordia can trigger a cell volume increase, an increase in the number of cells does not trigger a cell volume decrease. This phenomenon is termed compensation and suggests the existence of some systems for integration between cell cycling and cell enlargement in leaf primordia via cell-cell communication. The environmental adjustment of leaf expansion to light conditions and gravity is also summarized.
Effects of combination of leaf resources on competition in container mosquito larvae.
Reiskind, M H; Zarrabi, A A; Lounibos, L P
2012-08-01
Resource diversity is critical to fitness in many insect species, and may determine the coexistence of competitive species and the function of ecosystems. Plant material provides the nutritional base for numerous aquatic systems, yet the consequences of diversity of plant material have not been studied in aquatic container systems important for the production of mosquitoes. To address how diversity in leaf detritus affects container-inhabiting mosquitoes, we examined how leaf species affect competition between two container inhabiting mosquito larvae, Aedes aegypti and Aedes albopictus, that co-occur in many parts of the world. We tested the hypotheses that leaf species changes the outcome of intra- and interspecific competition between these mosquito species, and that combinations of leaf species affect competition in a manner not predictable based upon the response to each leaf species alone (i.e. the response to leaf combinations is non-additive). We find support for our first hypothesis that leaf species can affect competition, evidence that, in general, leaf combination alters competitive interactions, and no support that leaf combination impacts interspecific competition differently than intraspecific competition. We conclude that combinations of leaves increase mosquito production non-additively such that combinations of leaves act synergistically, in general, and result in higher total yield of adult mosquitoes in most cases, although certain leaf combinations for A. albopictus are antagonistic. We also conclude that leaf diversity does not have a different effect on interspecific competition between A. aegypti and A. albopictus, relative to intraspecific competition for each mosquito.
NASA Technical Reports Server (NTRS)
Liu, Z.; Ostrenga, D.; Vollmer, B.; Kempler, S.; Deshong, B.; Greene, M.
2015-01-01
The NASA Goddard Earth Sciences (GES) Data and Information Services Center (DISC) hosts and distributes GPM data within the NASA Earth Observation System Data Information System (EOSDIS). The GES DISC is also home to the data archive for the GPM predecessor, the Tropical Rainfall Measuring Mission (TRMM). Over the past 17 years, the GES DISC has served the scientific as well as other communities with TRMM data and user-friendly services. During the GPM era, the GES DISC will continue to provide user-friendly data services and customer support to users around the world. GPM products currently and to-be available: -Level-1 GPM Microwave Imager (GMI) and partner radiometer products, DPR products -Level-2 Goddard Profiling Algorithm (GPROF) GMI and partner products, DPR products -Level-3 daily and monthly products, DPR products -Integrated Multi-satellitE Retrievals for GPM (IMERG) products (early, late, and final) A dedicated Web portal (including user guides, etc.) has been developed for GPM data (http://disc.sci.gsfc.nasa.gov/gpm). Data services that are currently and to-be available include Google-like Mirador (http://mirador.gsfc.nasa.gov/) for data search and access; data access through various Web services (e.g., OPeNDAP, GDS, WMS, WCS); conversion into various formats (e.g., netCDF, HDF, KML (for Google Earth), ASCII); exploration, visualization, and statistical online analysis through Giovanni (http://giovanni.gsfc.nasa.gov); generation of value-added products; parameter and spatial subsetting; time aggregation; regridding; data version control and provenance; documentation; science support for proper data usage, FAQ, help desk; monitoring services (e.g. Current Conditions) for applications. The United User Interface (UUI) is the next step in the evolution of the GES DISC web site. It attempts to provide seamless access to data, information and services through a single interface without sending the user to different applications or URLs (e.g., search, access, subset, Giovanni, documents).
A Physiological and Behavioral Mechanism for Leaf Herbivore-Induced Systemic Root Resistance1[OPEN
Erb, Matthias; Robert, Christelle A.M.; Marti, Guillaume; Lu, Jing; Doyen, Gwladys R.; Villard, Neil; Barrière, Yves; Wolfender, Jean-Luc; Turlings, Ted C.J.
2015-01-01
Indirect plant-mediated interactions between herbivores are important drivers of community composition in terrestrial ecosystems. Among the most striking examples are the strong indirect interactions between spatially separated leaf- and root-feeding insects sharing a host plant. Although leaf feeders generally reduce the performance of root herbivores, little is known about the underlying systemic changes in root physiology and the associated behavioral responses of the root feeders. We investigated the consequences of maize (Zea mays) leaf infestation by Spodoptera littoralis caterpillars for the root-feeding larvae of the beetle Diabrotica virgifera virgifera, a major pest of maize. D. virgifera strongly avoided leaf-infested plants by recognizing systemic changes in soluble root components. The avoidance response occurred within 12 h and was induced by real and mimicked herbivory, but not wounding alone. Roots of leaf-infested plants showed altered patterns in soluble free and soluble conjugated phenolic acids. Biochemical inhibition and genetic manipulation of phenolic acid biosynthesis led to a complete disappearance of the avoidance response of D. virgifera. Furthermore, bioactivity-guided fractionation revealed a direct link between the avoidance response of D. virgifera and changes in soluble conjugated phenolic acids in the roots of leaf-attacked plants. Our study provides a physiological mechanism for a behavioral pattern that explains the negative effect of leaf attack on a root-feeding insect. Furthermore, it opens up the possibility to control D. virgifera in the field by genetically mimicking leaf herbivore-induced changes in root phenylpropanoid patterns. PMID:26430225
NASA Astrophysics Data System (ADS)
Coudeyras, N.; Sinou, J.-J.; Nacivet, S.
2009-01-01
Brake squeal noise is still an issue since it generates high warranty costs for the automotive industry and irritation for customers. Key parameters must be known in order to reduce it. Stability analysis is a common method of studying nonlinear phenomena and has been widely used by the scientific and the engineering communities for solving disc brake squeal problems. This type of analysis provides areas of stability versus instability for driven parameters, thereby making it possible to define design criteria. Nevertheless, this technique does not permit obtaining the vibrating state of the brake system and nonlinear methods have to be employed. Temporal integration is a well-known method for computing the dynamic solution but as it is time consuming, nonlinear methods such as the Harmonic Balance Method (HBM) are preferred. This paper presents a novel nonlinear method called the Constrained Harmonic Balance Method (CHBM) that works for nonlinear systems subject to flutter instability. An additional constraint-based condition is proposed that omits the static equilibrium point (i.e. the trivial static solution of the nonlinear problem that would be obtained by applying the classical HBM) and therefore focuses on predicting both the Fourier coefficients and the fundamental frequency of the stationary nonlinear system. The effectiveness of the proposed nonlinear approach is illustrated by an analysis of disc brake squeal. The brake system under consideration is a reduced finite element model of a pad and a disc. Both stability and nonlinear analyses are performed and the results are compared with a classical variable order solver integration algorithm. Therefore, the objectives of the following paper are to present not only an extension of the HBM (CHBM) but also to demonstrate an application to the specific problem of disc brake squeal with extensively parametric studies that investigate the effects of the friction coefficient, piston pressure, nonlinear stiffness and structural damping.
NASA Astrophysics Data System (ADS)
Hales, Antonio S.; Barlow, M. J.; Crawford, I. A.; Casassus, S.
2017-04-01
We have conducted a search for optical circumstellar absorption lines in the spectra of 16 debris disc host stars. None of the stars in our sample showed signs of emission line activity in either Hα, Ca II or Na I, confirming their more evolved nature. Four stars were found to exhibit narrow absorption features near the cores of the photospheric Ca II and Na I D lines (when Na I D data were available). We analyse the characteristics of these spectral features to determine whether they are of circumstellar or interstellar origins. The strongest evidence for circumstellar gas is seen in the spectrum of HD 110058, which is known to host a debris disc observed close to edge-on. This is consistent with a recent ALMA detection of molecular gas in this debris disc, which shows many similarities to the β Pictoris system.
Newton, Kymberly; Zubrod, Jochen P; Englert, Dominic; Lüderwald, Simon; Schell, Theresa; Baudy, Patrick; Konschak, Marco; Feckler, Alexander; Schulz, Ralf; Bundschuh, Mirco
2018-06-05
Waterborne exposure towards fungicides is known to trigger negative effects in aquatic leaf-associated microbial decomposers and leaf-shredding macroinvertebrates. We expected similar effects when these organisms use leaf material from terrestrial plants that were treated with systemic fungicides as a food source since the fungicides may remain within the leaves when entering aquatic systems. To test this hypothesis, we treated black alder (Alnus glutinosa) trees with a tap water control or a systemic fungicide mixture (azoxystrobin, cyprodinil, quinoxyfen, and tebuconazole) at two worst-case application rates. Leaves of these trees were used in an experiment targeting alterations in two functions provided by leaf-associated microorganisms, namely the decomposition and conditioning of leaf material. The latter was addressed via the food-choice response of the amphipod shredder Gammarus fossarum. During a second experiment, the potential impact of long-term consumption of leaves from trees treated with systemic fungicides on G. fossarum was assessed. Systemic fungicide treatment altered the resource quality of the leaf material resulting in trends of increased fungal spore production and an altered community composition of leaf-associated fungi. These changes in turn caused a significant preference of Gammarus for microbially conditioned leaves that had received the highest fungicide treatment over control leaves. This higher food quality ultimately resulted in a higher gammarid growth (up to 300% increase) during the long-term feeding assay. Although the underlying mechanisms still need to be addressed, the present study demonstrates a positive indirect response in aquatic organisms due to systemic pesticide application in a terrestrial system. As the effects from the introduction of plant material treated with systemic fungicides strongly differ from those mediated via other pathways (e.g., waterborne exposure), our study provides a novel perspective of fungicide-triggered effects in aquatic detritus-based food webs. Copyright © 2018 Elsevier Ltd. All rights reserved.
Leaf ontogeny and demography explain photosynthetic seasonality in Amazon evergreen forests
NASA Astrophysics Data System (ADS)
Wu, J.; Albert, L.; Lopes, A. P.; Restrepo-Coupe, N.; Hayek, M.; Wiedemann, K. T.; Guan, K.; Stark, S. C.; Prohaska, N.; Tavares, J. V.; Marostica, S. F.; Kobayashi, H.; Ferreira, M. L.; Campos, K.; Silva, R. D.; Brando, P. M.; Dye, D. G.; Huxman, T. E.; Huete, A. R.; Nelson, B. W.; Saleska, S. R.
2015-12-01
Photosynthetic seasonality couples the evolutionary ecology of plant leaves to large-scale rhythms of carbon and water exchanges that are important feedbacks to climate. However, the extent, magnitude, and controls on photosynthetic seasonality of carbon-rich tropical forests are poorly resolved, controversial in the remote sensing literature, and inadequately represented in most earth system models. Here we show that ecosystem-scale phenology (measured by photosynthetic capacity), rather than environmental seasonality, is the primary driver of photosynthetic seasonality at four Amazon evergreen forests spanning gradients in rainfall seasonality, forest composition, and flux seasonality. We further demonstrate that leaf ontogeny and demography explain most of this ecosystem phenology at two central Amazon evergreen forests, using a simple leaf-cohort canopy model that integrates eddy covariance-derived CO2 fluxes, novel near-surface camera-detected leaf phenology, and ground observations of litterfall and leaf physiology. The coordination of new leaf growth and old leaf divestment (litterfall) during the dry season shifts canopy composition towards younger leaves with higher photosynthetic efficiency, driving large seasonal increases (~27%) in ecosystem photosynthetic capacity. Leaf ontogeny and demography thus reconciles disparate observations of forest seasonality from leaves to eddy flux towers to satellites. Strategic incorporation of such whole-plant coordination processes as phenology and ontogeny will improve ecological, evolutionary and earth system theories describing tropical forests structure and function, allowing more accurate representation of forest dynamics and feedbacks to climate in earth system models.
Transient events in bright debris discs: Collisional avalanches revisited
NASA Astrophysics Data System (ADS)
Thebault, P.; Kral, Q.
2018-01-01
Context. A collisional avalanche is set off by the breakup of a large planetesimal, releasing vast amounts of small unbound grains that enter a debris disc located further away from the star, triggering there a collisional chain reaction that could potentially create detectable transient structures. Aims: We investigate this mechanism, using for the first time a fully self-consistent code coupling dynamical and collisional evolutions. We also quantify for the first time the photometric evolution of the system and investigate whether or not avalanches could explain the short-term luminosity variations recently observed in some extremely bright debris discs. Methods: We use the state-of-the-art LIDT-DD code. We consider an avalanche-favoring A6V star, and two set-ups: a "cold disc" case, with a dust release at 10 au and an outer disc extending from 50 to 120 au, and a "warm disc" case with the release at 1 au and a 5-12 au outer disc. We explore, in addition, two key parameters: the density (parameterized by its optical depth τ) of the main outer disc and the amount of dust released by the initial breakup. Results: We find that avalanches could leave detectable structures on resolved images, for both "cold" and "warm" disc cases, in discs with τ of a few 10-3, provided that large dust masses (≳1020-5 × 1022 g) are initially released. The integrated photometric excess due to an avalanche is relatively limited, less than 10% for these released dust masses, peaking in the λ 10-20 μm domain and becoming insignificant beyond 40-50 μm. Contrary to earlier studies, we do not obtain stronger avalanches when increasing τ to higher values. Likewise, we do not observe a significant luminosity deficit, as compared to the pre-avalanche level, after the passage of the avalanche. These two results concur to make avalanches an unlikely explanation for the sharp luminosity drops observed in some extremely bright debris discs. The ideal configuration for observing an avalanche would be a two-belt structure, with an inner belt (at 1 or 10 au for the "warm" and "cold" disc cases, respectively) of fractional luminosity f ≳ 10-4 where breakups of massive planetesimals occur, and a more massive outer belt, with τ of a few 10-3, into which the avalanche chain reaction develops and propagates.
Value-added Data Services at the Goddard Earth Sciences Data and Information Services Center
NASA Technical Reports Server (NTRS)
Leptoukh, Gregory G.; Alcott, Gary T.; Kempler, Steven J.; Lynnes, Christopher S.; Vollmer, Bruce E.
2004-01-01
The NASA Goddard Earth Sciences Data and Information Services Center (GES DISC), in addition to serving the Earth Science community as one of the major Distributed Active Archives Centers (DAACs), provides much more than just data. Among the value-added services available to general users are subsetting data spatially and/or by parameter, online analysis (to avoid downloading unnecessarily all the data), and assistance in obtaining data from other centers. Services available to data producers and high-volume users include consulting on building new products with standard formats and metadata and construction of data management systems. A particularly useful service is data processing at the DISC (i.e., close to the input data) with the users algorithm. This can take a number of different forms: as a configuration-managed algorithm within the main processing stream; as a stand-alone program next to the on-line data storage; as build-it-yourself code within the Near-Archive Data Mining (NADM) system; or as an on-the-fly analysis with simple algorithms embedded into the web-based tools. Partnerships between the GES DISC and scientists, both producers and users, allow the scientists to concentrate on science, while the GES DISC handles the data management, e.g., formats, integration, and data processing. The existing data management infrastructure at the GES DISC supports a wide spectrum of options: from simple data support to sophisticated on-line analysis tools, producing economies of scale and rapid time-to-deploy. At the same time, such partnerships allow the GES DISC to serve the user community more efficiently and to better prioritize on-line holdings. Several examples of successful partnerships are described in the presentation.
Fischer, William S.; Wall, Michael; McDermott, Michael P.; Kupersmith, Mark J.; Feldon, Steven E.
2015-01-01
Purpose. To describe the methods used by the Photographic Reading Center (PRC) of the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT) and to report baseline assessments of papilledema severity in participants. Methods. Stereoscopic digital images centered on the optic disc and the macula were collected using certified personnel and photographic equipment. Certification of the camera system included standardization and calibration using a model eye. Lay readers assessed disc photos of all eyes using the Frisén grade and performed quantitative measurements of papilledema. Frisén grades by PRC were compared with site investigator clinical grades. Spearman rank correlations were used to quantify associations among disc features and selected clinical variables. Results. Frisén grades according to the PRC and site investigator's grades, matched exactly in 48% of the study eyes and 42% of the fellow eyes and within one grade in 94% of the study eyes and 92% of the fellow eyes. Frisén grade was strongly correlated (r > 0.65, P < 0.0001) with quantitative measures of disc area. Cerebrospinal fluid pressure was weakly associated with Frisén grade and disc area determinations (r ≤ 0.31). Neither Frisén grade nor any fundus feature was associated with perimetric mean deviation. Conclusions. In a prospective clinical trial, lay readers agreed reasonably well with physicians in assessing Frisén grade. Standardization of camera systems enhanced consistency of photographic quality across study sites. Images were affected more by sensors with poor dynamic range than by poor resolution. Frisén grade is highly correlated with quantitative assessment of disc area. (ClinicalTrials.gov number, NCT01003639.) PMID:26024112
Fischer, William S; Wall, Michael; McDermott, Michael P; Kupersmith, Mark J; Feldon, Steven E
2015-05-01
To describe the methods used by the Photographic Reading Center (PRC) of the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT) and to report baseline assessments of papilledema severity in participants. Stereoscopic digital images centered on the optic disc and the macula were collected using certified personnel and photographic equipment. Certification of the camera system included standardization and calibration using a model eye. Lay readers assessed disc photos of all eyes using the Frisén grade and performed quantitative measurements of papilledema. Frisén grades by PRC were compared with site investigator clinical grades. Spearman rank correlations were used to quantify associations among disc features and selected clinical variables. Frisén grades according to the PRC and site investigator's grades, matched exactly in 48% of the study eyes and 42% of the fellow eyes and within one grade in 94% of the study eyes and 92% of the fellow eyes. Frisén grade was strongly correlated (r > 0.65, P < 0.0001) with quantitative measures of disc area. Cerebrospinal fluid pressure was weakly associated with Frisén grade and disc area determinations (r ≤ 0.31). Neither Frisén grade nor any fundus feature was associated with perimetric mean deviation. In a prospective clinical trial, lay readers agreed reasonably well with physicians in assessing Frisén grade. Standardization of camera systems enhanced consistency of photographic quality across study sites. Images were affected more by sensors with poor dynamic range than by poor resolution. Frisén grade is highly correlated with quantitative assessment of disc area. (ClinicalTrials.gov number, NCT01003639.).
Terzi, Rabiye; Saruhan, Neslihan; Sağlam, A; Nar, Hatice; Kadioğlu, A
2009-12-01
We studied the changes in antioxidant system and chlorophyll fluorescence parameters in post-stress emerging Ctenanthe setosa (Rosc.) Eichler (Marantaceae) plants (PSE plants) having reduced leaf area under drought stress causing leaf rolling and re-watering. PSE plants were compared to primary stressed plants (PS) in previous studies. The parameters were measured at different visual leaf rolling scores from 1 to 4 (1 is unrolled, 4 is tightly rolled and the others is intermediate form). Water potentials and stomatal conductance of leaves were gradually decreased during leaf rolling. Similarly, maximum quantum efficiency of open PS II center and quantum yield of PS II decreased during the rolling period. Non-photochemical quenching of chlorophyll fluorescence decreased at score 2 then increased while photochemical quenching did not change during leaf rolling. Electron transport rate decreased only at score 4 but approximately reached to score 1 level after re-watering. Superoxide dismutase activity was not constant at all leaf rolling scores. Ascorbate peroxidase, catalase and glutathione reductase activities generally tended to increase during leaf rolling. Lipid peroxidation and H 2 O 2 content increased at score 2 but decreased at the later scores. On the other hand, O 2 .- production increased during the rolling period. After re-watering of the plants having score 4 of leaf rolling, antioxidant enzyme activities were lower than those of score 1. Other physiological parameters also tended to reach the value of score 1. The results indicated that PSE plants gained drought tolerance by reducing leaf area effectively induced their antioxidant systems and protected the photosynthesis under drought stress similar to PS plants.
Linear dynamic coupling in geared rotor systems
NASA Technical Reports Server (NTRS)
David, J. W.; Mitchell, L. D.
1986-01-01
The effects of high frequency oscillations caused by the gear mesh, on components of a geared system that can be modeled as rigid discs are analyzed using linear dynamic coupling terms. The coupled, nonlinear equations of motion for a disc attached to a rotating shaft are presented. The results of a trial problem analysis show that the inclusion of the linear dynamic coupling terms can produce significant changes in the predicted response of geared rotor systems, and that the produced sideband responses are greater than the unbalanced response. The method is useful in designing gear drives for heavy-lift helicopters, industrial speed reducers, naval propulsion systems, and heavy off-road equipment.
Argonaute-based programmable RNase as a tool for cleavage of highly-structured RNA.
Dayeh, Daniel M; Cantara, William A; Kitzrow, Jonathan P; Musier-Forsyth, Karin; Nakanishi, Kotaro
2018-06-12
The recent identification and development of RNA-guided enzymes for programmable cleavage of target nucleic acids offers exciting possibilities for both therapeutic and biotechnological applications. However, critical challenges such as expensive guide RNAs and inability to predict the efficiency of target recognition, especially for highly-structured RNAs, remain to be addressed. Here, we introduce a programmable RNA restriction enzyme, based on a budding yeast Argonaute (AGO), programmed with cost-effective 23-nucleotide (nt) single-stranded DNAs as guides. DNA guides offer the advantage that diverse sequences can be easily designed and purchased, enabling high-throughput screening to identify optimal recognition sites in the target RNA. Using this DNA-induced slicing complex (DISC) programmed with 11 different guide DNAs designed to span the sequence, sites of cleavage were identified in the 352-nt human immunodeficiency virus type 1 5'-untranslated region. This assay, coupled with primer extension and capillary electrophoresis, allows detection and relative quantification of all DISC-cleavage sites simultaneously in a single reaction. Comparison between DISC cleavage and RNase H cleavage reveals that DISC not only cleaves solvent-exposed sites, but also sites that become more accessible upon DISC binding. This study demonstrates the advantages of the DISC system for programmable cleavage of highly-structured, functional RNAs.
The lamppost model: effects of photon trapping, the bottom lamp and disc truncation
NASA Astrophysics Data System (ADS)
Niedźwiecki, Andrzej; Zdziarski, Andrzej A.
2018-04-01
We study the lamppost model, in which the primary X-ray sources in accreting black-hole systems are located symmetrically on the rotation axis on both sides of the black hole surrounded by an accretion disc. We show the importance of the emission of the source on the opposite side to the observer. Due to gravitational light bending, its emission can increase the direct (i.e., not re-emitted by the disc) flux by as much as an order of magnitude. This happens for near to face-on observers when the disc is even moderately truncated. For truncated discs, we also consider effects of emission of the top source gravitationally bent around the black hole. We also present results for the attenuation of the observed radiation with respect to that emitted by the lamppost as functions of the lamppost height, black-hole spin and the degree of disc truncation. This attenuation, which is due to the time dilation, gravitational redshift and the loss of photons crossing the black-hole horizon, can be as severe as by several orders of magnitude for low lamppost heights. We also consider the contribution to the observed flux due to re-emission by optically-thick matter within the innermost stable circular orbit.
Study report on laser storage and retrieval of image data
NASA Technical Reports Server (NTRS)
Becker, C. H.
1976-01-01
The theoretical foundation is presented for a system of real-time nonphotographic and nonmagnetic digital laser storage and retrieval of image data. The system utilizes diffraction-limited laser focusing upon thin metal films, melting elementary holes in the metal films in laser focus. The metal films are encapsulated in rotating flexible mylar discs which act as the permanent storage carries. Equal sized holes encompass two dimensional digital ensembles of information bits which are time-sequentially (bit by bit) stored and retrieved. The bits possess the smallest possible size, defined by the Rayleigh criterion of coherent physical optics. Space and time invariant reflective read-out of laser discs with a small laser, provides access to the stored digital information. By eliminating photographic and magnetic data processing, which characterize the previous state of the art, photographic grain, diffusion, and gamma-distortion do not exist. Similarly, magnetic domain structures, magnetic gaps, and magnetic read-out are absent with a digital laser disc system.
An inner warp in the DoAr 44 T Tauri transition disc
NASA Astrophysics Data System (ADS)
Casassus, Simon; Avenhaus, Henning; Pérez, Sebastián; Navarro, Víctor; Cárcamo, Miguel; Marino, Sebastián; Cieza, Lucas; Quanz, Sascha P.; Alarcón, Felipe; Zurlo, Alice; Osses, Axel; Rannou, Fernando R.; Román, Pablo E.; Barraza, Marcelo
2018-07-01
Optical/IR images of transition discs (TDs) have revealed deep intensity decrements in the rings of HAeBes HD 142527 and HD 100453 that can be interpreted as shadowing from sharply tilted inner discs, such that the outer discs are directly exposed to stellar light. Here we report similar dips in SPHERE+IRDIS differential polarized imaging (DPI) of T Tauri DoAr 44. With a fairly axially symmetric ring in the sub-mm radio continuum, DoAr 44 is likely also a warped system. We constrain the warp geometry by comparing radiative transfer predictions with the DPI data in H band (Qϕ(H)) and with a re-processing of archival 336 GHz ALMA observations. The observed DPI shadows have coincident radio counterparts, but the intensity drops are much deeper in Qϕ(H) (˜88 per cent), compared to the shallow drops at 336 GHz (˜24 per cent). Radiative transfer predictions with an inner disc tilt of ˜30 ± 5 deg approximately account for the observations. ALMA long-baseline observations should allow the observation of the warped gas kinematics inside the cavity of DoAr 44.
Effect of grinding with diamond-disc and -bur on the mechanical behavior of a Y-TZP ceramic.
Pereira, G K R; Amaral, M; Simoneti, R; Rocha, G C; Cesar, P F; Valandro, L F
2014-09-01
This study compared the effects of grinding on the surface micromorphology, phase transformation (t→m), biaxial flexural strength and structural reliability (Weibull analysis) of a Y-TZP (Lava) ceramic using diamond-discs and -burs. 170 discs (15×1.2mm) were produced and divided into 5 groups: without treatment (Ctrl, as-sintered), and ground with 4 different systems: extra-fine (25µm, Xfine) and coarse diamond-bur (181µm, Coarse), 600-grit (25µm, D600) and 120-grit diamond-disc (160µm, D120). Grinding with burs was performed using a contra-angle handpiece (T2-Revo R170, Sirona), while for discs (Allied) a Polishing Machine (Ecomet, Buehler) was employed, both under water-cooling. Micromorphological analysis showed distinct patterns generated by grinding with discs and burs, independent of grit size. There was no statistical difference for characteristic strength values (MPa) between smaller grit sizes (D600 - 1050.08 and Xfine - 1171.33), although they presented higher values compared to Ctrl (917.58). For bigger grit sizes, a significant difference was observed (Coarse - 1136.32>D120 - 727.47). Weibull Modules were statistically similar between the tested groups. Within the limits of this study, from a micromorphological point-of-view, the treatments performed did not generate similar effects, so from a methodological point-of-view, diamond-discs should not be employed to simulate clinical abrasion performed with diamond-burs on Y-TZP ceramics. Copyright © 2014 Elsevier Ltd. All rights reserved.
Savoldelli, Charles; Bouchard, Pierre-Olivier; Loudad, Raounak; Baque, Patrick; Tillier, Yannick
2012-07-01
This study aims at analysing the stresses distribution in the temporomandibular joint (TMJ) using a complete high-resolution finite element model (FE Model). This model is used here to analyse the stresses distribution in the discs during a closing jaw cycle. In the end, this model enables the prediction of the stress evolution in the TMJ disc submitted to various loadings induced by mandibular trauma, surgery or parafunction. The geometric data for the model were obtained from MRI and CT scans images of a healthy male patient. Surface and volume meshes were successively obtained using a 3D image segmentation software (AMIRA(®)). Bone components of skull and mandible, both of joint discs, temporomandibular capsules and ligaments and dental arches were meshed as separate bodies. The volume meshes were transferred to the FE analysis software (FORGE(®)). Material properties were assigned for each region. Boundary conditions for closing jaw simulations were represented by different load directions of jaws muscles. The von Mises stresses distribution in both joint discs during closing conditions was analyzed. The pattern of von Mises stresses in the TMJ discs is non-symmetric and changed continuously during jaw movement. Maximal stress is reached on the surface disc in areas in contact with others bodies. The three-dimension finite element model of masticatory system will make it possible to simulate different conditions that appear to be important in the cascade of events leading to joint damage.
NASA Astrophysics Data System (ADS)
Phuong, Nguyen Thi; Diep, Pham Ngoc; Dutrey, Anne; Chapillon, Edwige; Darriulat, Pierre; Guilloteau, Stéphane; Hoai, Do Thi; Tuyet Nhung, Pham; Tang, Ya-Wen; Thao, Nguyen Thi; Tuan-Anh, Pham
2018-03-01
Observations by the Atacama Large Millimetre/sub-millimetre Array of the dust continuum and 13CO(3–2) millimetre emissions of the triple stellar system GG Tau A are analysed, giving evidence for a rotating gas disc and a concentric and coplanar dust ring. The present work complements an earlier analysis (Tang et al.) by exploring detailed properties of the gas disc. A 95% confidence level upper limit of 0.24″ (34 au) is placed on the disc scale height at a distance of 1″ (140 au) from the central stars. Evidence for Keplerian rotation of the gas disc is presented, with the rotation velocity reaching ∼3.1 km s‑1 at 1″ from the central stars, and a 99% confidence level upper limit of 9% is placed on relative contribution from a possible in-fall velocity. Variations of the intensity across the disc area are studied in detail and confirm the presence of a hot spot in the south-eastern quadrant. However several other significant intensity variations, in particular a depression in the northern direction, are also revealed. Variations of the intensity are found to be positively correlated to variations of the line width. Possible contributions to the measured line width are reviewed, suggesting an increase of the disc temperature and opacity with decreasing distance from the stars.
Barbaro, V; Boccanera, G; Daniele, C; Grigioni, M; Palombo, A
1995-09-01
A fatigue life test, by accelerating the beat rate, simulates several years of virtual life of a prosthetic heart valve in a short period of time. The correlation between the in vivo life of a valve and in vitro testing expectations is as yet not well established, but reproducible test conditions yield precious information about wear and failure. The paper reports a qualitative analysis of mechanical valve wear as part of a comparison program designed to investigate the significance of fatigue testing with the ultimate aim of defining standard guidelines for these type of tests. Two tilting disc valves (29 mm) were subjected to 16 years of fatigue life simulated by means of a Rowan Ash fatigue tester (accelerated rate of 1,200 bpm). Fatigue-induced effects on valve disc and ring surfaces were observed under a monitor microscope to identify wear sites and patterns. A high speed cinematographic system was used to investigate the mechanisms responsible for the wear (wear modes). Valve closure was inspected at a 6,000 frame/s rate. Because of disc rotation during the tilting movement, the points of contact between disc and ring are distributed all around the disc edge but focally on the ring. On both sides of the disc, the surfaces present ring-like concentric grooves. After 16 years of fatigue life the valves showed neither severe wear nor alteration of their fluidodynamic behavior in the pulsatile flow test.
NASA Astrophysics Data System (ADS)
Chen, M.; Butler, E. E.; Wythers, K. R.; Kattge, J.; Ricciuto, D. M.; Thornton, P. E.; Atkin, O. K.; Flores-Moreno, H.; Reich, P. B.
2017-12-01
In order to better estimate the carbon budget of the globe, accurately simulating gross primary productivity (GPP) in earth system models is critical. When upscaling leaf level photosynthesis to the canopy, climate models uses different big-leaf schemes. About half of the state-of-the-art earth system models use a "two-big-leaf" scheme that partitions canopies into direct and diffusively illuminated fractions to reduce high bias of GPP simulated by one-big-leaf models. Some two-big-leaf models, such as ACME (identical in this respect to CLM 4.5) add leaf area index (LAI) and stem area index (SAI) together when calculating canopy radiation transfer. This treatment, however, will result in higher fraction of sunlit leaves. It will also lead to an artificial overestimation of canopy nitrogen content. Here we introduce a new algorithm of simulating SAI in a two-big-leaf model. The new algorithm reduced the sunlit leave fraction of the canopy and conserved the nitrogen content from leaf to canopy level. The lower fraction of sunlit leaves reduced global GPP especially in tropical area. Compared to the default model, for the past 100 years (1909-2009), the averaged global annual GPP is lowered by 4.11 PgC year-1 using this new algorithm.
Targeted manipulation of leaf form via local growth repression.
Malinowski, Robert; Kasprzewska, Ania; Fleming, Andrew J
2011-06-01
A classical view is that leaf shape is the result of local promotion of growth linked to cell proliferation. However, an alternative hypothesis is that leaf form is the result of local repression of growth in an otherwise growing system. Here we show that leaf form can indeed be manipulated in a directed fashion by local repression of growth. We show that targeting expression of an inhibitor of a cyclin-dependent kinase (KRP1) to the sinus area of developing leaves of Arabidopsis leads to local growth repression and the formation of organs with extreme lobing, including generation of leaflet-like organs. Directing KRP1 expression to other regions of the leaf using an miRNA target sequence tagging approach also leads to predictable novel leaf forms, and repression of growth in the leaf margin blocks the outgrowth of lobes, leading to a smoother perimeter. In addition, we show that decreased growth around the perimeter and across the leaf abaxial surface leads to a change in 3D form, as predicted by mechanical models of leaf growth. Our analysis provides experimental evidence that local repression of growth influences leaf shape, suggesting that it could be part of the mechanism of morphogenesis in plants in the context of an otherwise growing system. © 2011 The Authors. The Plant Journal © 2011 Blackwell Publishing Ltd.
Brushed permanent magnet DC MLC motor operation in an external magnetic field.
Yun, J; St Aubin, J; Rathee, S; Fallone, B G
2010-05-01
Linac-MR systems for real-time image-guided radiotherapy will utilize the multileaf collimators (MLCs) to perform conformal radiotherapy and tumor tracking. The MLCs would be exposed to the external fringe magnetic fields of the linac-MR hybrid systems. Therefore, an experimental investigation of the effect of an external magnetic field on the brushed permanent magnet DC motors used in some MLC systems was performed. The changes in motor speed and current were measured for varying external magnetic field strengths up to 2000 G generated by an EEV electromagnet. These changes in motor characteristics were measured for three orientations of the motor in the external magnetic field, mimicking changes in motor orientations due to installation and/or collimator rotations. In addition, the functionality of the associated magnetic motor encoder was tested. The tested motors are used with the Varian 120 leaf Millennium MLC (Maxon Motor half leaf and full leaf motors) and the Varian 52 leaf MKII MLC (MicroMo Electronics leaf motor) including a carriage motor (MicroMo Electronics). In most cases, the magnetic encoder of the motors failed prior to any damage to the gearbox or the permanent magnet motor itself. This sets an upper limit of the external magnetic field strength on the motor function. The measured limits of the external magnetic fields were found to vary by the motor type. The leaf motor used with a Varian 52 leaf MKII MLC system tolerated up to 450 +/- 10 G. The carriage motor tolerated up to 2000 +/- 10 G field. The motors used with the Varian 120 leaf Millennium MLC system were found to tolerate a maximum of 600 +/- 10 G. The current Varian MLC system motors can be used for real-time image-guided radiotherapy coupled to a linac-MR system, provided the fringe magnetic fields at their locations are below the determined tolerance levels. With the fringe magnetic fields of linac-MR systems expected to be larger than the tolerance levels determined, some form of magnetic shielding would be required.
Nearby stars of the Galactic disc and halo - IV
NASA Astrophysics Data System (ADS)
Fuhrmann, Klaus
2008-02-01
The Milky Way Galaxy has an age of about 13 billion years. Solar-type stars evolve all the long way to the realm of degenerate objects on essentially this time-scale. This, as well as the particular advantage that the Sun offers through reliable differential spectroscopic analyses, render these stars the ideal tracers for the fossil record of our parent spiral. Astrophysics is a science that is known to be notoriously plagued by selection effects. The present work - with a major focus in this fourth contribution on model atmosphere analyses of spectroscopic binaries and multiple star systems - aims at a volume-complete sample of about 300 nearby F-, G-, and K-type stars that particularly avoids any kinematical or chemical pre-selection from the outset. It thereby provides an unbiased record of the local stellar populations - the ancient thick disc and the much younger thin disc. On this base, the detailed individual scrutiny of the long-lived stars of both populations unveils the thick disc as a single-burst component with a local normalization of no less than 20 per cent. This enormous fraction, combined with its much larger scaleheight, implies a mass for the thick disc that is comparable to that of the thin disc. On account of its completely different mass-to-light ratio the thick disc thereby becomes the dark side of the Milky Way, an ideal major source for baryonic dark matter. This massive, ancient population consequently challenges any gradual build-up scenario for our parent spiral. Even more, on the supposition that the Galaxy is not unusual, the thick disc - as it emerges from this unbiased spectroscopic work - particularly challenges the hierarchical cold-dark-matter-dominated formation picture for spiral galaxies in general.
NASA Astrophysics Data System (ADS)
Iacob Tudose, E. T.; Zaharia, C.
2018-06-01
The spinning disc (SD) technology has received increased attention in the last years due to its enhanced fluid flow features resulting in improved property transfers. The actual study focuses on characterization of the flow within a spinning disc system based on experimental data used to establish the residence time distribution (RTD) and its dependence on the feeding liquid flowrate and the disc rotational speed. To obtain these data, an inert tracer (sodium chloride) was injected as a pulse input in the liquid stream entering the disc and the salt concentration of the liquid leaving the disc was continuously recorded. The obtained data indicate that an increase in the liquid flowrate from 10 L/h to 30 L/h determines a narrower RTD function. Also, at rotational speed of 200 rpm, the residence time distribution is broader than that for 500 rpm and 800 rpm. The RTD data suggest that depending on the needed flow characteristics, one can choose a certain flowrate and rotational speed domain for its application. Also, the SD technology was used to process textile wastewater treated with bentonite (as both coagulation and discoloration agent) in order to investigate whether the quality indicators such as the total suspended solid content, turbidity and discoloration, can be improved. The experimental results are promising since the discoloration and the removals of suspended solids attained values of over 40%, and respectively, 50 %, depending on the effluent flowrate (10 l/h and 30 L/h), and the disc rotational speed (200 rpm, 550 rpm and 850 rpm) without any other addition of chemicals, or initiation of other simultaneous treatment processes (e.g., advanced oxidative, or reductive, or biochemical processes). This recommends spinning disc technology as a suitable and promising tool to improve different wastewater characteristics.
Iwai, Kazunori; Koyama, Koji; Okada, Takashi; Nakazato, Koichi; Takahashi, Ray; Matsumoto, Shingo; Yamamoto, Yosuke; Hiranuma, Kenji
2016-01-01
Lumbar intervertebral disc degeneration (LDD) frequently occurs in athletes. Associations between LDD and trunk muscles still remain unclear. This study examined whether there is an association between the prevalence of LDD and the symmetry and size of the cross-sectional areas (CSAs) of the trunk muscles in combat sports athletes. Participants in this study were 151 collegiate male combat sports athletes. A total of 755 lumbar intervertebral discs from L1-2 to L5-S1 in 151 athletes were assessed using magnetic resonance imaging (MRI) and a comprehensive grading system of LDD (grades I-V). All 151 athletes were divided into 2 groups: LDD and non-LDD. CSAs of trunk muscles at the L3-4 disc level were measured using MRI. Sixty-nine athletes had LDD at 1 or more disc levels (45.7 %). The LDD grade for the lower 2 disc levels was significantly higher than that for the other disc levels (p < 0.001). The CSAs of the left and right sides in trunk muscles were significantly asymmetrical, independent of the LDD which was prevalent in the disc levels (obliques: p = 0.040; quadratus lumborum: p < 0.001). The relative CSAs of trunk muscles to their body weight in the LDD group were significantly smaller than those in the non-LDD group (rectus abdominis: p = 0.011; obliques: p = 0.024; quadratus lumborum: p = 0.006; lumbar erector spinae plus multifidus: p = 0.001). This study suggests that the prevalence of LDD is associated with asymmetrical and relatively smaller CSAs of trunk muscles in combat sports athletes.
Jaszczak, Jacob S; Wolpe, Jacob B; Bhandari, Rajan; Jaszczak, Rebecca G; Halme, Adrian
2016-10-01
Damage to Drosophila melanogaster imaginal discs activates a regeneration checkpoint that (1) extends larval development and (2) coordinates the regeneration of the damaged disc with the growth of undamaged discs. These two systemic responses to damage are both mediated by Dilp8, a member of the insulin/insulin-like growth factor/relaxin family of peptide hormones, which is released by regenerating imaginal discs. Growth coordination between regenerating and undamaged imaginal discs is dependent on Dilp8 activation of nitric oxide synthase (NOS) in the prothoracic gland (PG), which slows the growth of undamaged discs by limiting ecdysone synthesis. Here we demonstrate that the Drosophila relaxin receptor homolog Lgr3, a leucine-rich repeat-containing G-protein-coupled receptor, is required for Dilp8-dependent growth coordination and developmental delay during the regeneration checkpoint. Lgr3 regulates these responses to damage via distinct mechanisms in different tissues. Using tissue-specific RNA-interference disruption of Lgr3 expression, we show that Lgr3 functions in the PG upstream of NOS, and is necessary for NOS activation and growth coordination during the regeneration checkpoint. When Lgr3 is depleted from neurons, imaginal disc damage no longer produces either developmental delay or growth inhibition. To reconcile these discrete tissue requirements for Lgr3 during regenerative growth coordination, we demonstrate that Lgr3 activity in both the CNS and PG is necessary for NOS activation in the PG following damage. Together, these results identify new roles for a relaxin receptor in mediating damage signaling to regulate growth and developmental timing. Copyright © 2016 by the Genetics Society of America.
The ALMA early science view of FUor/EXor objects - V. Continuum disc masses and sizes
NASA Astrophysics Data System (ADS)
Cieza, Lucas A.; Ruíz-Rodríguez, Dary; Perez, Sebastian; Casassus, Simon; Williams, Jonathan P.; Zurlo, Alice; Principe, David A.; Hales, Antonio; Prieto, Jose L.; Tobin, John J.; Zhu, Zhaohuan; Marino, Sebastian
2018-03-01
Low-mass stars build a significant fraction of their total mass during short outbursts of enhanced accretion known as FUor and EXor outbursts. FUor objects are characterized by a sudden brightening of ˜5 mag at visible wavelengths within 1 yr and remain bright for decades. EXor objects have lower amplitude outbursts on shorter time-scales. Here we discuss a 1.3 mm Atacama Large Millimeter/submillimeter Array (ALMA) mini-survey of eight outbursting sources (three FUors, four EXors, and the borderline object V1647 Ori) in the Orion Molecular Cloud. While previous papers in this series discuss the remarkable molecular outflows observed in the three FUor objects and V1647 Ori, here we focus on the continuum data and the differences and similarities between the FUor and EXor populations. We find that FUor discs are significantly more massive (˜80-600 MJup) than the EXor objects (˜0.5-40 MJup). We also report that the EXor sources lack the prominent outflows seen in the FUor population. Even though our sample is small, the large differences in disc masses and outflow activity suggest that the two types of objects represent different evolutionary stages. The FUor sources seem to be rather compact (Rc < 20-40 au) and to have a smaller characteristic radius for a given disc mass when compared to T Tauri stars. V1118 Ori, the only known close binary system in our sample, is shown to host a disc around each one of the stellar components. The disc around HBC 494 is asymmetric, hinting at a structure in the outer disc or the presence of a second disc.
DISC1 Causes Associative Memory and Neurodevelopmental Defects in Fruit Flies
Furukubo-Tokunaga, Katsuo; Kurita, Kazuki; Honjo, Ken; Pandey, Himani; Ando, Tetsuya; Takayama, Kojiro; Arai, Yuko; Mochizuki, Hiroaki; Ando, Mai; Kamiya, Atsushi; Sawa, Akira
2016-01-01
Originally found in a Scottish family with diverse mental disorders, the DISC1 protein has been characterized as an intracellular scaffold protein that associates with diverse binding partners in neural development. To explore its functions in a genetically tractable system, we expressed the human DISC1 in fruit flies (Drosophila melanogaster). As in mammalian neurons, DISC1 is localized to diverse subcellular domains of developing fly neurons including the nuclei, axons and dendrites. Overexpression of DISC1 impairs associative memory. Experiments with deletion/mutation constructs have revealed the importance of amino terminal domain (46–290) for memory suppression whereas carboxyl domain (598–854) and the amino terminal residues (1–45) including the nuclear localization signal (NLS1) are dispensable. DISC1 overexpression also causes suppression of axonal and dendritic branching of mushroom body neurons, which mediate a variety of cognitive functions in the fly brain. Analyses with deletion constructs reveal that protein domains 598–854 and 349–402 are both required for the suppression of axonal branching while amino-terminal domains including NLS1 are dispensable. In contrast, NLS1 was required for the suppression of dendritic branching, suggesting a mechanism involving gene expression. Moreover, domain 403–596 is also required for the suppression of dendritic branching. We also show that overexpression of DISC1 suppresses glutamatergic synaptogenesis in developing neuromuscular junctions. Deletion/mutation experiments have revealed the importance of protein domains 403–596 and 349–402 for synaptic suppression, while amino terminal domains including NLS1 are dispensable. Finally, we show that DISC1 functionally interacts with the fly homolog of Dysbindin (DTNBP1) via direct protein-protein interaction in developing synapses. PMID:26976042
TERASHIMA, ICHIRO; ARAYA, TAKAO; MIYAZAWA, SHIN-ICHI; SONE, KOSEI; YANO, SATOSHI
2004-01-01
• Background and Aims The paper by Monsi and Saeki in 1953 (Japanese Journal of Botany 14: 22–52) was pioneering not only in mathematical modelling of canopy photosynthesis but also in eco-developmental studies of seasonal changes in leaf canopies. • Scope Construction and maintenance mechanisms of efficient photosynthetic systems at three different scaling levels—single leaves, herbaceous plants and trees—are reviewed mainly based on the nitrogen optimization theory. First, the nitrogen optimization theory with respect to the canopy and the single leaf is briefly introduced. Secondly, significance of leaf thickness in CO2 diffusion in the leaf and in leaf photosynthesis is discussed. Thirdly, mechanisms of adjustment of photosynthetic properties of the leaf within the herbaceous plant individual throughout its life are discussed. In particular, roles of sugar sensing, redox control and of cytokinin are highlighted. Finally, the development of a tree is considered. • Conclusions Various mechanisms contribute to construction and maintenance of efficient photosynthetic systems. Molecular backgrounds of these ecologically important mechanisms should be clarified. The construction mechanisms of the tree cannot be explained solely by the nitrogen optimization theory. It is proposed that the pipe model theory in its differential form could be a potential tool in future studies in this research area. PMID:15598701
NASA Astrophysics Data System (ADS)
Zhang, Jun; Dong, Chengcheng; Zhang, Hui; Li, Song; Song, Aiguo
2018-05-01
This paper presents a novel lander anchoring system based on sawing method for asteroid exploration. The system is composed of three robotic arms, three cutting discs, and a control system. The discs mounted at the end of the arms are able to penetrate into the rock surface of asteroids. After the discs cut into the rock surface, the self-locking function of the arms provides forces to fix the lander on the surface. Modeling, trajectory planning, simulations, mechanism design, and prototype fabrication of the anchoring system are discussed, respectively. The performances of the system are tested on different kinds of rocks, at different sawing angles, locations, and speeds. Results show that the system can cut 15 mm deep into granite rock in 180 s at sawing angle of 60°, with the average power of 58.41 W, and the "weight on bit" (WOB) of 8.637 N. The 7.8 kg anchoring system is capable of providing omni-directional anchoring forces, at least 225 N normal and 157 N tangent to the surface of the rock. The system has the advantages of low-weight, low energy consumption and balance forces, high anchoring efficiency and reliability, and could enable the lander to move and sample or assist astronauts and robots in walking and sampling on asteroids.
Chasing discs around O-type (proto)stars: Evidence from ALMA observations
NASA Astrophysics Data System (ADS)
Cesaroni, R.; Sánchez-Monge, Á.; Beltrán, M. T.; Johnston, K. G.; Maud, L. T.; Moscadelli, L.; Mottram, J. C.; Ahmadi, A.; Allen, V.; Beuther, H.; Csengeri, T.; Etoka, S.; Fuller, G. A.; Galli, D.; Galván-Madrid, R.; Goddi, C.; Henning, T.; Hoare, M. G.; Klaassen, P. D.; Kuiper, R.; Kumar, M. S. N.; Lumsden, S.; Peters, T.; Rivilla, V. M.; Schilke, P.; Testi, L.; van der Tak, F.; Vig, S.; Walmsley, C. M.; Zinnecker, H.
2017-06-01
Context. Circumstellar discs around massive stars could mediate the accretion onto the star from the infalling envelope, and could minimize the effects of radiation pressure. Despite such a crucial role, only a few convincing candidates have been provided for discs around deeply embedded O-type (proto)stars. Aims: In order to establish whether disc-mediated accretion is the formation mechanism for the most massive stars, we have searched for circumstellar, rotating discs around a limited sample of six luminous (>105L⊙) young stellar objects. These objects were selected on the basis of their IR and radio properties in order to maximize the likelihood of association with disc+jet systems. Methods: We used ALMA with 0.̋2 resolution to observe a large number of molecular lines typical of hot molecular cores. In this paper we limit our analysis to two disc tracers (methyl cyanide, CH3CN, and its isotopologue, 13CH3CN), and an outflow tracer (silicon monoxide, SiO). Results: We reveal many cores, although their number depends dramatically on the target. We focus on the cores that present prominent molecular line emission. In six of these a velocity gradient is seen across the core,three of which show evidence of Keplerian-like rotation. The SiO data reveal clear but poorly collimated bipolar outflow signatures towards two objects only. This can be explained if real jets are rare (perhaps short-lived) in very massive objects and/or if stellar multiplicity significantly affects the outflow structure.For all cores with velocity gradients, the velocity field is analysed through position-velocity plots to establish whether the gas is undergoing rotation with νrot ∝ R- α, as expected for Keplerian-like discs. Conclusions: Our results suggest that in three objects we are observing rotation in circumstellar discs, with three more tentative cases, and one core where no evidence for rotation is found. In all cases but one, we find that the gas mass is less than the mass of any embedded O-type star, consistent with the (putative) discs undergoing Keplerian-like rotation. With the caveat of low number statistics, we conclude that the disc detection rate could be sensitive to the evolutionary stage of the young stellar object. In young, deeply embedded sources, the evidence for discs could be weak because of confusion with the surrounding envelope, while in the most evolved sources the molecular component of the disc could have already been dispersed. Only in those objects that are at an intermediate stage of the evolution would the molecular disc be sufficiently prominent and relatively less embedded to be detectable by mm/submm observations.
USDA-ARS?s Scientific Manuscript database
Early leaf spot caused by the fungus Cercospora arachidicola, and late leaf spot caused by the fungus Cercosporidium personatum, are major yield-reducing diseases of peanut (Arachis hypogaea L.) in the southeastern U.S. Effective control of both leaf spots can be reached with integrated disease man...
NASA Astrophysics Data System (ADS)
Wang, Aiming; Cheng, Xiaohan; Meng, Guoying; Xia, Yun; Wo, Lei; Wang, Ziyi
2017-03-01
Identification of rotor unbalance is critical for normal operation of rotating machinery. The single-disc and single-span rotor, as the most fundamental rotor-bearing system, has attracted research attention over a long time. In this paper, the continuous single-disc and single-span rotor is modeled as a homogeneous and elastic Euler-Bernoulli beam, and the forces applied by bearings and disc on the shaft are considered as point forces. A fourth-order non-homogeneous partial differential equation set with homogeneous boundary condition is solved for analytical solution, which expresses the unbalance response as a function of position, rotor unbalance and the stiffness and damping coefficients of bearings. Based on this analytical method, a novel Measurement Point Vector Method (MPVM) is proposed to identify rotor unbalance while operating. Only a measured unbalance response registered for four selected cross-sections of the rotor-shaft under steady-state operating conditions is needed when using the method. Numerical simulation shows that the detection error of the proposed method is very small when measurement error is negligible. The proposed method provides an efficient way for rotor balancing without test runs and external excitations.
Simonin, Kevin A; Roddy, Adam B; Link, Percy; Apodaca, Randy; Tu, Kevin P; Hu, Jia; Dawson, Todd E; Barbour, Margaret M
2013-12-01
During daylight hours, the isotope composition of leaf water generally approximates steady-state leaf water isotope enrichment model predictions. However, until very recently there was little direct confirmation that isotopic steady-state (ISS) transpiration in fact exists. Using isotope ratio infrared spectroscopy (IRIS) and leaf gas exchange systems we evaluated the isotope composition of transpiration and the rate of change in leaf water isotopologue storage (isostorage) when leaves were exposed to variable environments. In doing so, we developed a method for controlling the absolute humidity entering the gas exchange cuvette for a wide range of concentrations without changing the isotope composition of water vapour. The measurement system allowed estimation of (18)O enrichment both at the evaporation site and for bulk leaf water, in the steady state and the non-steady state. We show that non-steady-state effects dominate the transpiration isoflux even when leaves are at physiological steady state. Our results suggest that a variable environment likely prevents ISS transpiration from being achieved and that this effect may be exacerbated by lengthy leaf water turnover times due to high leaf water contents. © 2013 John Wiley & Sons Ltd.
Mishra, Monali P.; Padhy, Rabindra N.
2013-01-01
Objectives To screen methanolic leaf extracts of 21 timber-yielding plants for antibacterial activity against nine species of uropathogenic bacteria isolated from clinical samples of a hospital (Enterococcus faecalis, Staphylococcus aureus, Acinetobacter baumannii, Citrobacter freundii, Enterobacter aerogenes, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Pseudomonas aeruginosa). Methods Bacterial strains were subjected to antibiotic sensitivity tests by the Kirby–Bauer's disc diffusion method. The antibacterial potentiality of leaf extracts was monitored by the agar-well diffusion method with multidrug-resistant (MDR) strains of nine uropathogens. Results Two Gram-positive isolates, E. faecalis and S. aureus, were resistant to 14 of the 18 antibiotics used. Gram-negative isolates A. baumannii, C. freundii, E. aerogenes, E. coli, K. pneumoniae, P. mirabilis, and P. aeruginosa were resistant to 10, 12, 9, 11, 11, 10, and 11 antibiotics, respectively, of the 14 antibiotics used. Methanolic leaf extracts of Anogeissus acuminata had the maximum zone of inhibition size—29 mm against S. aureus and 28 mm against E. faecalis and P. aeruginosa. Cassia tora had 29 mm as the zone of inhibition size for E. faecalis, E. aerogenes, and P. aeruginosa. Based on the minimum inhibitory concentration and minimum bactericidal concentration values, the most effective 10 plants against uropathogens could be arranged in decreasing order as follows: C. tora > A. acuminata > Schleichera oleosa > Pterocarpus santalinus > Eugenia jambolana > Bridelia retusa > Mimusops elengi > Stereospermum kunthianum > Tectona grandis > Anthocephalus cadamba. The following eight plants had moderate control capacity: Artocarpus heterophyllus, Azadirachta indica, Dalbergia latifolia, Eucalyptus citriodora, Gmelina arborea, Pongamia pinnata, Pterocarpus marsupium, and Shorea robusta. E. coli, followed by A. baumannii, C. freundii, E. aerogenes, P. mirabilis, and P. aeruginosa were controlled by higher amounts/levels of leaf extracts. Phytochemicals of all plants were qualitatively estimated. Conclusions A majority of timber-yielding plants studied had in vitro control capacity against MDR uropathogenic bacteria. PMID:24524024
Wolff, Jonas O; Lovtsova, Julia; Gorb, Elena; Dai, Zhendong; Ji, Aihong; Zhao, Zhihui; Jiang, Nan; Gorb, Stanislav N
2017-03-01
Silks play an important role in the life of various arthropods. A highly neglected prerequisite to make versatile use of silks is sufficient attachment to substrates. Although there have been some studies on the structure and mechanics of silk anchorages of spiders, for insects only anecdotal reports on attachment-associated spinning behaviour exist. Here, we experimentally studied the silk attachment of the pupae and last instar caterpillars of the tea bagworm Eumeta minuscula (Butler 1881) (Lepidoptera, Psychidae) to the leaves of its host plant Ilex chinensis We found that the bagworms spin attachment discs, which share some structural features with those of spiders, like a plaque consisting of numerous overlaid, looped glue-coated silk fibres and the medially attaching suspension thread. Although the glue, which coats the fibres, cannot spread and adhere very well to the leaf surface, high pull-off forces were measured, yielding a mean safety factor (force divided by the animal weight) of 385.6. Presumably, the bagworms achieve this by removal of the leaf epidermis prior to silk attachment, which exposes the underlying tissue that represents a much better bonding site. This ensures a reliable attachment during the immobile, vulnerable pupal stage. This is the first study on the biomechanics and structure of silk attachments to substrates in insects. © 2017 The Author(s).
Dobbertin, Matthias; Eilmann, Britta; Bleuler, Peter; Giuggiola, Arnaud; Graf Pannatier, Elisabeth; Landolt, Werner; Schleppi, Patrick; Rigling, Andreas
2010-03-01
In Valais, Switzerland, Scots pines (Pinus sylvestris L.) are declining, mainly following drought. To assess the impact of drought on tree growth and survival, an irrigation experiment was initiated in 2003 in a mature pine forest, approximately doubling the annual precipitation. Tree crown transparency (lack of foliage) and leaf area index (LAI) were annually assessed. Seven irrigated and six control trees were felled in 2006, and needles, stem discs and branches were taken for growth analysis. Irrigation in 2004 and 2005, both with below-average precipitation, increased needle size, area and mass, stem growth and, with a 1-year delay, shoot length. This led to a relative decrease in tree crown transparency (-14%) and to an increase in stand LAI (+20%). Irrigation increased needle length by 70%, shoot length by 100% and ring width by 120%, regardless of crown transparency. Crown transparency correlated positively with mean needle size, shoot length and ring width and negatively with specific leaf area. Trees with high crown transparency (low growth, short needles) experienced similar increases in needle mass and growth with irrigation than trees with low transparency (high growth, long needles), indicating that seemingly declining trees were able to 'recover' when water supply became sufficient. A simple drought index before and during the irrigation explained most of the variation found in the parameters for both irrigated and control trees.
Where can a Trappist-1 planetary system be produced?
NASA Astrophysics Data System (ADS)
Haworth, Thomas J.; Facchini, Stefano; Clarke, Cathie J.; Mohanty, Subhanjoy
2018-04-01
We study the evolution of protoplanetary discs that would have been precursors of a Trappist-1-like system under the action of accretion and external photoevaporation in different radiation environments. Dust grains swiftly grow above the critical size below which they are entrained in the photoevaporative wind, so although gas is continually depleted, dust is resilient to photoevaporation after only a short time. This means that the ratio of the mass in solids (dust plus planetary) to the mass in gas rises steadily over time. Dust is still stripped early on, and the initial disc mass required to produce the observed 4 M⊕ of Trappist-1 planets is high. For example, assuming a Fatuzzo & Adams distribution of UV fields, typical initial disc masses have to be >30 per cent the stellar (which are still Toomre Q stable) for the majority of similar mass M dwarfs to be viable hosts of the Trappist-1 planets. Even in the case of the lowest UV environments observed, there is a strong loss of dust due to photoevaporation at early times from the weakly bound outer regions of the disc. This minimum level of dust loss is a factor of 2 higher than that which would be lost by accretion on to the star during 10 Myr of evolution. Consequently, even in these least irradiated environments, discs that are viable Trappist-1 precursors need to be initially massive (>10 per cent of the stellar mass).
System and Method for Finite Element Simulation of Helicopter Turbulence
NASA Technical Reports Server (NTRS)
McFarland, R. E. (Inventor); Dulsenberg, Ken (Inventor)
1999-01-01
The present invention provides a turbulence model that has been developed for blade-element helicopter simulation. This model uses an innovative temporal and geometrical distribution algorithm that preserves the statistical characteristics of the turbulence spectra over the rotor disc, while providing velocity components in real time to each of five blade-element stations along each of four blades. for a total of twenty blade-element stations. The simulator system includes a software implementation of flight dynamics that adheres to the guidelines for turbulence set forth in military specifications. One of the features of the present simulator system is that it applies simulated turbulence to the rotor blades of the helicopter, rather than to its center of gravity. The simulator system accurately models the rotor penetration into a gust field. It includes time correlation between the front and rear of the main rotor, as well as between the side forces felt at the center of gravity and at the tail rotor. It also includes features for added realism, such as patchy turbulence and vertical gusts in to which the rotor disc penetrates. These features are realized by a unique real time implementation of the turbulence filters. The new simulator system uses two arrays one on either side of the main rotor to record the turbulence field and to produce time-correlation from the front to the rear of the rotor disc. The use of Gaussian Interpolation between the two arrays maintains the statistical properties of the turbulence across the rotor disc. The present simulator system and method may be used in future and existing real-time helicopter simulations with minimal increase in computational workload.
Comparison of the bond strength of stainless steel orthodontic brackets bonded to crown porcelains.
Chay, Siew Han; Wattanapayungkul, Pranee; Yap, Adrian U Jin; Loh, Poey Ling; Chung, Sew Meng
2005-05-01
The bond strengths and mode of failure of stainless steel orthodontic brackets bonded to the newer all-ceramic crown systems has not been fully investigated. To compare the shear-peel bond strengths and modes of failure of stainless steel Begg orthodontic brackets bonded to all-ceramic crown systems (Finesse, Empress II) and a conventional feldsphatic crown porcelain (Vita Omega 900). Fifteen flat-surface discs of three crown porcelains (Finesse, Vita Omega 900, Empress II) were made and mounted in acrylic moulds. The discs were pumiced, etched with phosphoric acid, primed with silane, and a flat stainless steel Begg bracket bonded to each disc with a chemical cure composite resin (Unite Bond). The discs were stored for one week in water and debonded with a sheer-peel load in an Instron uniaxial testing system with a crosshead speed of 0.5 mm/min. The composite remnants on the ceramic surfaces were classified using the Adhesive Remnant Index (ARI). The bond strength of Finesse (15.03 +/- 1.90 MPa) was significantly greater (p < 0.001) than Vita Omega 900 11.51 +/- 2.35 MPa) and Empress II (11.12 +/- 1.78 MPa). There were no significant differences among the ARI scores. The mode of failure was a mixture of adhesive and cohesive failure. The results indicate that the bond strengths of stainless steel orthodontic brackets bonded to Finesse and Empress II porcelains are clinically acceptable.
Leverstein-van Hall, Maurine A; Waar, Karola; Muilwijk, Jan; Cohen Stuart, James
2013-11-01
The CLSI recommends a fixed 2 : 1 ratio of co-amoxiclav for broth microdilution susceptibility testing of Enterobacteriaceae, while EUCAST recommends a fixed 2 mg/L clavulanate concentration. The aims of this study were: (i) to determine the influence of a switch from CLSI to EUCAST methodology on Escherichia coli susceptibility rates; (ii) to compare susceptibility results obtained using EUCAST-compliant microdilution with those from disc diffusion and the Etest; and (iii) to evaluate the clinical outcome of patients with E. coli sepsis treated with co-amoxiclav in relation to the susceptibility results obtained using either method. Resistance rates were determined in three laboratories that switched from CLSI to EUCAST cards with the Phoenix system (Becton Dickinson) as well as in 17 laboratories that continued to use CLSI cards with the VITEK 2 system (bioMérieux). In one laboratory, isolates were simultaneously tested by both the Phoenix system and either disc diffusion (n = 471) or the Etest (n = 113). Medical and laboratory records were reviewed for E. coli sepsis patients treated with co-amoxiclav monotherapy. Only laboratories that switched methodology showed an increase in resistance rates - from 19% in 2010 to 31% in 2011 (P < 0.0001). All isolates that tested susceptible by microdilution were also susceptible by disc diffusion or the Etest, but of 326 isolates that tested resistant by microdilution, 43% and 59% tested susceptible by disc diffusion and the Etest, respectively. Among the 89 patients included there was a better correlation between clinical response and measured MICs using the Phoenix system than the Etest. EUCAST methodology resulted in higher co-amoxiclav E. coli resistance rates than CLSI methodology, but correlated better with clinical outcome. EUCAST-compliant microdilution and disc diffusion provided discrepant results.
Jamaludin, Amir; Lootus, Meelis; Kadir, Timor; Zisserman, Andrew; Urban, Jill; Battié, Michele C; Fairbank, Jeremy; McCall, Iain
2017-05-01
Investigation of the automation of radiological features from magnetic resonance images (MRIs) of the lumbar spine. To automate the process of grading lumbar intervertebral discs and vertebral bodies from MRIs. MR imaging is the most common imaging technique used in investigating low back pain (LBP). Various features of degradation, based on MRIs, are commonly recorded and graded, e.g., Modic change and Pfirrmann grading of intervertebral discs. Consistent scoring and grading is important for developing robust clinical systems and research. Automation facilitates this consistency and reduces the time of radiological analysis considerably and hence the expense. 12,018 intervertebral discs, from 2009 patients, were graded by a radiologist and were then used to train: (1) a system to detect and label vertebrae and discs in a given scan, and (2) a convolutional neural network (CNN) model that predicts several radiological gradings. The performance of the model, in terms of class average accuracy, was compared with the intra-observer class average accuracy of the radiologist. The detection system achieved 95.6% accuracy in terms of disc detection and labeling. The model is able to produce predictions of multiple pathological gradings that consistently matched those of the radiologist. The model identifies 'Evidence Hotspots' that are the voxels that most contribute to the degradation scores. Automation of radiological grading is now on par with human performance. The system can be beneficial in aiding clinical diagnoses in terms of objectivity of gradings and the speed of analysis. It can also draw the attention of a radiologist to regions of degradation. This objectivity and speed is an important stepping stone in the investigation of the relationship between MRIs and clinical diagnoses of back pain in large cohorts. Level 3.
DZ Chamaeleontis: a bona fide photoevaporating disc
NASA Astrophysics Data System (ADS)
Canovas, H.; Montesinos, B.; Schreiber, M. R.; Cieza, L. A.; Eiroa, C.; Meeus, G.; de Boer, J.; Ménard, F.; Wahhaj, Z.; Riviere-Marichalar, P.; Olofsson, J.; Garufi, A.; Rebollido, I.; van Holstein, R. G.; Caceres, C.; Hardy, A.; Villaver, E.
2018-02-01
Context. DZ Cha is a weak-lined T Tauri star (WTTS) surrounded by a bright protoplanetary disc with evidence of inner disc clearing. Its narrow Hα line and infrared spectral energy distribution suggest that DZ Cha may be a photoevaporating disc. Aims: We aim to analyse the DZ Cha star + disc system to identify the mechanism driving the evolution of this object. Methods: We have analysed three epochs of high resolution optical spectroscopy, photometry from the UV up to the sub-mm regime, infrared spectroscopy, and J-band imaging polarimetry observations of DZ Cha. Results: Combining our analysis with previous studies we find no signatures of accretion in the Hα line profile in nine epochs covering a time baseline of 20 yr. The optical spectra are dominated by chromospheric emission lines, but they also show emission from the forbidden lines [SII] 4068 and [OI] 6300Å that indicate a disc outflow. The polarized images reveal a dust depleted cavity of 7 au in radius and two spiral-like features, and we derive a disc dust mass limit of Mdust< 3 MEarth from the sub-mm photometry. No stellar (M⋆> 80 MJup) companions are detected down to 0.̋07 ( 8 au, projected). Conclusions: The negligible accretion rate, small cavity, and forbidden line emission strongly suggests that DZ Cha is currently at the initial stages of disc clearing by photoevaporation. At this point the inner disc has drained and the inner wall of the truncated outer disc is directly exposed to the stellar radiation. We argue that other mechanisms like planet formation or binarity cannot explain the observed properties of DZ Cha. The scarcity of objects like this one is in line with the dispersal timescale (≲105 yr) predicted by this theory. DZ Cha is therefore an ideal target to study the initial stages of photoevaporation. Based on observations collected at the European Organisation for Astronomical Research in the Southern Hemisphere under ESO programme 097.C-0536. Based on data obtained from the ESO Science Archive Facility under request number 250112.
Moving mode shape function approach for spinning disk and asymmetric disc brake squeal
NASA Astrophysics Data System (ADS)
Kang, Jaeyoung
2018-06-01
The solution approach of an asymmetric spinning disk under stationary friction loads requires the mode shape function fixed in the disk in the assumed mode method when the equations of motion is described in the space-fixed frame. This model description will be termed the 'moving mode shape function approach' and it allows us to formulate the stationary contact load problem in both the axisymmetric and asymmetric disk cases. Numerical results show that the eigenvalues of the time-periodic axisymmetric disk system are time-invariant. When the axisymmetry of the disk is broken, the positive real parts of the eigenvalues highly vary with the rotation of the disk in the slow speeds in such application as disc brake squeal. By using the Floquet stability analysis, it is also shown that breaking the axisymmetry of the disc alters the stability boundaries of the system.
Time variability of viscosity parameter in differentially rotating discs
NASA Astrophysics Data System (ADS)
Rajesh, S. R.; Singh, Nishant K.
2014-07-01
We propose a mechanism to produce fluctuations in the viscosity parameter (α) in differentially rotating discs. We carried out a nonlinear analysis of a general accretion flow, where any perturbation on the background α was treated as a passive/slave variable in the sense of dynamical system theory. We demonstrate a complete physical picture of growth, saturation and final degradation of the perturbation as a result of the nonlinear nature of coupled system of equations. The strong dependence of this fluctuation on the radial location in the accretion disc and the base angular momentum distribution is demonstrated. The growth of fluctuations is shown to have a time scale comparable to the radial drift time and hence the physical significance is discussed. The fluctuation is found to be a power law in time in the growing phase and we briefly discuss its statistical significance.
Showalter, Brent L; Beckstein, Jesse C; Martin, John T; Beattie, Elizabeth E; Espinoza Orías, Alejandro A; Schaer, Thomas P; Vresilovic, Edward J; Elliott, Dawn M
2012-07-01
Experimental measurement and normalization of in vitro disc torsion mechanics and collagen content for several animal species used in intervertebral disc research and comparing these with the human disc. To aid in the selection of appropriate animal models for disc research by measuring torsional mechanical properties and collagen content. There is lack of data and variability in testing protocols for comparing animal and human disc torsion mechanics and collagen content. Intervertebral disc torsion mechanics were measured and normalized by disc height and polar moment of inertia for 11 disc types in 8 mammalian species: the calf, pig, baboon, goat, sheep, rabbit, rat, and mouse lumbar discs, and cow, rat, and mouse caudal discs. Collagen content was measured and normalized by dry weight for the same discs except the rat and the mouse. Collagen fiber stretch in torsion was calculated using an analytical model. Measured torsion parameters varied by several orders of magnitude across the different species. After geometric normalization, only the sheep and pig discs were statistically different from human discs. Fiber stretch was found to be highly dependent on the assumed initial fiber angle. The collagen content of the discs was similar, especially in the outer annulus where only the calf and goat discs were statistically different from human. Disc collagen content did not correlate with torsion mechanics. Disc torsion mechanics are comparable with human lumbar discs in 9 of 11 disc types after normalization by geometry. The normalized torsion mechanics and collagen content of the multiple animal discs presented are useful for selecting and interpreting results for animal disc models. Structural organization of the fiber angle may explain the differences that were noted between species after geometric normalization.
Automated rice leaf disease detection using color image analysis
NASA Astrophysics Data System (ADS)
Pugoy, Reinald Adrian D. L.; Mariano, Vladimir Y.
2011-06-01
In rice-related institutions such as the International Rice Research Institute, assessing the health condition of a rice plant through its leaves, which is usually done as a manual eyeball exercise, is important to come up with good nutrient and disease management strategies. In this paper, an automated system that can detect diseases present in a rice leaf using color image analysis is presented. In the system, the outlier region is first obtained from a rice leaf image to be tested using histogram intersection between the test and healthy rice leaf images. Upon obtaining the outlier, it is then subjected to a threshold-based K-means clustering algorithm to group related regions into clusters. Then, these clusters are subjected to further analysis to finally determine the suspected diseases of the rice leaf.
Halic, Tansel; Kockara, Sinan; Bayrak, Coskun; Rowe, Richard
2010-10-07
Until quite recently spinal disorder problems in the U.S. have been operated by fusing cervical vertebrae instead of replacement of the cervical disc with an artificial disc. Cervical disc replacement is a recently approved procedure in the U.S. It is one of the most challenging surgical procedures in the medical field due to the deficiencies in available diagnostic tools and insufficient number of surgical practices For physicians and surgical instrument developers, it is critical to understand how to successfully deploy the new artificial disc replacement systems. Without proper understanding and practice of the deployment procedure, it is possible to injure the vertebral body. Mixed reality (MR) and virtual reality (VR) surgical simulators are becoming an indispensable part of physicians' training, since they offer a risk free training environment. In this study, MR simulation framework and intricacies involved in the development of a MR simulator for the rasping procedure in artificial cervical disc replacement (ACDR) surgery are investigated. The major components that make up the MR surgical simulator with motion tracking system are addressed. A mixed reality surgical simulator that targets rasping procedure in the artificial cervical disc replacement surgery with a VICON motion tracking system was developed. There were several challenges in the development of MR surgical simulator. First, the assembly of different hardware components for surgical simulation development that involves knowledge and application of interdisciplinary fields such as signal processing, computer vision and graphics, along with the design and placements of sensors etc . Second challenge was the creation of a physically correct model of the rasping procedure in order to attain critical forces. This challenge was handled with finite element modeling. The third challenge was minimization of error in mapping movements of an actor in real model to a virtual model in a process called registration. This issue was overcome by a two-way (virtual object to real domain and real domain to virtual object) semi-automatic registration method. The applicability of the VICON MR setting for the ACDR surgical simulator is demonstrated. The main stream problems encountered in MR surgical simulator development are addressed. First, an effective environment for MR surgical development is constructed. Second, the strain and the stress intensities and critical forces are simulated under the various rasp instrument loadings with impacts that are applied on intervertebral surfaces of the anterior vertebrae throughout the rasping procedure. Third, two approaches are introduced to solve the registration problem in MR setting. Results show that our system creates an effective environment for surgical simulation development and solves tedious and time-consuming registration problems caused by misalignments. Further, the MR ACDR surgery simulator was tested by 5 different physicians who found that the MR simulator is effective enough to teach the anatomical details of cervical discs and to grasp the basics of the ACDR surgery and rasping procedure.
Mixed reality simulation of rasping procedure in artificial cervical disc replacement (ACDR) surgery
2010-01-01
Background Until quite recently spinal disorder problems in the U.S. have been operated by fusing cervical vertebrae instead of replacement of the cervical disc with an artificial disc. Cervical disc replacement is a recently approved procedure in the U.S. It is one of the most challenging surgical procedures in the medical field due to the deficiencies in available diagnostic tools and insufficient number of surgical practices For physicians and surgical instrument developers, it is critical to understand how to successfully deploy the new artificial disc replacement systems. Without proper understanding and practice of the deployment procedure, it is possible to injure the vertebral body. Mixed reality (MR) and virtual reality (VR) surgical simulators are becoming an indispensable part of physicians’ training, since they offer a risk free training environment. In this study, MR simulation framework and intricacies involved in the development of a MR simulator for the rasping procedure in artificial cervical disc replacement (ACDR) surgery are investigated. The major components that make up the MR surgical simulator with motion tracking system are addressed. Findings A mixed reality surgical simulator that targets rasping procedure in the artificial cervical disc replacement surgery with a VICON motion tracking system was developed. There were several challenges in the development of MR surgical simulator. First, the assembly of different hardware components for surgical simulation development that involves knowledge and application of interdisciplinary fields such as signal processing, computer vision and graphics, along with the design and placements of sensors etc . Second challenge was the creation of a physically correct model of the rasping procedure in order to attain critical forces. This challenge was handled with finite element modeling. The third challenge was minimization of error in mapping movements of an actor in real model to a virtual model in a process called registration. This issue was overcome by a two-way (virtual object to real domain and real domain to virtual object) semi-automatic registration method. Conclusions The applicability of the VICON MR setting for the ACDR surgical simulator is demonstrated. The main stream problems encountered in MR surgical simulator development are addressed. First, an effective environment for MR surgical development is constructed. Second, the strain and the stress intensities and critical forces are simulated under the various rasp instrument loadings with impacts that are applied on intervertebral surfaces of the anterior vertebrae throughout the rasping procedure. Third, two approaches are introduced to solve the registration problem in MR setting. Results show that our system creates an effective environment for surgical simulation development and solves tedious and time-consuming registration problems caused by misalignments. Further, the MR ACDR surgery simulator was tested by 5 different physicians who found that the MR simulator is effective enough to teach the anatomical details of cervical discs and to grasp the basics of the ACDR surgery and rasping procedure PMID:20946594
Wu, Yushan; Gong, Wanzhuo; Wang, Yangmei; Yong, Taiwen; Yang, Feng; Liu, Weigui; Wu, Xiaoling; Du, Junbo; Shu, Kai; Liu, Jiang; Liu, Chunyan; Yang, Wenyu
2018-03-29
Leaf anatomy and the stomatal development of developing leaves of plants have been shown to be regulated by the same light environment as that of mature leaves, but no report has yet been written on whether such a long-distance signal from mature leaves regulates the total leaf area of newly emerged leaves. To explore this question, we created an investigation in which we collected data on the leaf area, leaf mass per area (LMA), leaf anatomy, cell size, cell number, gas exchange and soluble sugar content of leaves from three soybean varieties grown under full sunlight (NS), shaded mature leaves (MS) or whole plants grown in shade (WS). Our results show that MS or WS cause a marked decline both in leaf area and LMA in newly developing leaves. Leaf anatomy also showed characteristics of shade leaves with decreased leaf thickness, palisade tissue thickness, sponge tissue thickness, cell size and cell numbers. In addition, in the MS and WS treatments, newly developed leaves exhibited lower net photosynthetic rate (Pn), stomatal conductance (Gs) and transpiration rate (E), but higher carbon dioxide (CO 2 ) concentration in the intercellular space (Ci) than plants grown in full sunlight. Moreover, soluble sugar content was significantly decreased in newly developed leaves in MS and WS treatments. These results clearly indicate that (1) leaf area, leaf anatomical structure, and photosynthetic function of newly developing leaves are regulated by a systemic irradiance signal from mature leaves; (2) decreased cell size and cell number are the major cause of smaller and thinner leaves in shade; and (3) sugars could possibly act as candidate signal substances to regulate leaf area systemically.
NASA Technical Reports Server (NTRS)
Shim, J.; Leonardi, S. J.
1972-01-01
The wettabilities and heat transfer rates of microfog jets (oil-mist nozzle flows) impinging on a heated rotating disc were determined under an inert atmosphere of nitrogen at temperatures ranging from 600 to 800 F. The results are discussed in relation to the various factors involved in the microfog lubricant application systems. Two novel reclassifying nozzles and a vortex mist generator were also studied.
NASA Astrophysics Data System (ADS)
Shinoda, Masataka; Saito, Kimihiro; Kondo, Takao; Ishimoto, Tsutomu; Nakaoki, Ariyoshi
2003-02-01
We have investigated high-density near-field readout using a solid immersion lens with a high refractive index. By using a glass material with a high refractive index of 2.08, we developed an optical pick-up with the effective numerical aperture of 1.8. We could observe a clear eye pattern for a 50 GB capacity disc in 120 mm diameter. We confirmed that the near-field readout system is promising method of realizing a high-density optical disc system.
Exorcising Maxwell's Demon from Liboff's Three-Channel Conundrum
NASA Astrophysics Data System (ADS)
Opatrný, Tomáš; Mišáková, Zuzana
2011-02-01
We study a model proposed by Liboff (Found. Phys. Lett. 10:89, 1997) to violate the second law of thermodynamics. Discs are moving without friction in three connected channels inclined by π/3 with respect to each other. Based on the geometry considerations, it was argued that eventually all the discs end up in the middle channel regardless of their initial positions. This would mean a decrease of the entropy of the system and violation of the second law. We argue that no such anomalous behavior occurs in the system.
Ultra Compact Optical Pickup with Integrated Optical System
NASA Astrophysics Data System (ADS)
Nakata, Hideki; Nagata, Takayuki; Tomita, Hironori
2006-08-01
Smaller and thinner optical pickups are needed for portable audio-visual (AV) products and notebook personal computers (PCs). We have newly developed an ultra compact recordable optical pickup for Mini Disc (MD) that measures less than 4 mm from the disc surface to the bottom of the optical pickup, making the optical system markedly compact. We have integrated all the optical components into an objective lens actuator moving unit, while fully satisfying recording and playback performance requirements. In this paper, we propose an ultra compact optical pickup applicable to portable MD recorders.
Breedy, Odalisca; Guzman, Hector M
2018-01-05
The genus Adelogorgia is distinguished from other holaxonians in having conspicuously ornamented double-disc sclerites and leaf clubs in the coenenchyme, and non-mineralised axis cores. The two eastern Pacific species currently recognised as Adelogorgia are diagnosed and illustrated. Three new species for the genus are described from new localities and depth ranges. Analysis of external and internal characters, especially sclerite colours and sizes, and colony colour, shape and branching, allows separating the species. An identification key to the five species is provided, as well as a character table for comparisons. This study was based on newly collected specimens from 50 to 200 m deep, and re-examination of all historical material. We conclude that the genus comprises five valid species with a wider distribution than previously reported. This research is a contribution to the octocoral systematics and biodiversity from mesophotic and deep waters.
Transgenic tobacco expressing Pinellia ternata agglutinin confers enhanced resistance to aphids.
Yao, Jianhong; Pang, Yongzhen; Qi, Huaxiong; Wan, Bingliang; Zhao, Xiuyun; Kong, Weiwen; Sun, Xiaofen; Tang, Kexuan
2003-12-01
Tobacco leaf discs were transformed with a plasmid, pBIPTA, containing the selectable marker neomycin phosphotransferase gene (nptII) and Pinellia ternata agglutinin gene (pta) via Agrobacterium tumefaciens-mediated transformation. Thirty-two independent transgenic tobacco plants were regenerated. PCR and Southern blot analyses confirmed that the pta gene had integrated into the plant genome and northern blot analysis revealed transgene expression at various levels in transgenic plants. Genetic analysis confirmed Mendelian segregation of the transgene in T1 progeny. Insect bioassays showed that transgenic plants expressing PTA inhibited significantly the growth of peach potato aphid (Myzus persicae Sulzer). This is the first report that transgenic plants expressing pta confer enhanced resistance to aphids. Our study indicates that the pta gene can be used as a supplement to the snowdrop (Galanthus nivalis) lectin gene (gna) in the control of aphids, a sap-sucking insect pest causing significant yield losses of crops.
Xu, Xuenong; Enkegaard, Annie
2010-01-01
The prey preference of polyphagous predators plays an important role in suppressing different species of pest insects. In this study the prey preference of the predatory mite, Amblyseius swirskii (Athias-Henriot) (Acari: Phytoseiidae) was examined between nymphs of the twospotted spider mite, Tetranychus urticae Koch (Acari: Tetranychidae) and first instar larvae of the western flower thrips, Frankliniella occidentalis (Pergande) (Thysanoptera: Thripidae), as well as between active and chrysalis spider mite protonymphs and active and chrysalis spider mite deutonymphs. The study was done in the laboratory on bean leaf discs at 25 ± 1° C and 70 ± 5% RH. Amblyseius swirskii had a clear preference for thrips compared to both spider mite protonymphs and deutonymphs. About twice as many thrips as spider mites were consumed. Amblyseius swirskii did not show a preference between active and chrysalis stages of spider mites.
Some current research in rotating-disc systems.
Owen, J M; Wilson, M
2001-05-01
Rotating-disc systems are used to model the flow and heat transfer that occurs inside the cooling-air systems of gas-turbine engines. In this paper, recent computational and experimental research in three systems is discussed: rotor-stator systems, rotating cavities with superposed flow and buoyancy-induced flow in a rotating cavity. Discussion of the first two systems concentrates respectively on pre-swirl systems and rotating cavities with a peripheral inflow and outflow of cooling air. Buoyancy-induced flow in a rotating cavity is one of the most difficult problems facing computationalists and experimentalists, and there are similarities between the circulation in the Earth's atmosphere and the flow inside gas-turbine rotors. For this case, results are presented for heat transfer in sealed annuli and in rotating cavities with an axial throughflow of cooling air.
ERIC Educational Resources Information Center
Innovative Systems Research, Inc., Pennsauken, NJ.
Twelve different conversion plans were delineated and evaluated in the performance of this study effort. An indepth technical, financial, and cost/benefit analysis was included. One plan was determined to be distinctively more cost-effective than any of the other plans because it provided a technically feasible system that assured the maximum…
Heintze, Siegward Dietmar; Forjanic, Monika
2008-10-01
To evaluate the effect of the multiple-use of a three-step rubber-based polishing system on the polishing performance with and without a disinfection/sterilization protocol with prolonged disinfection (overnight). The three-step polishing system Astropol was applied under standardized contact pressure of 2 N on 320 grit pre-roughened flat composite specimens of Tetric EvoCeram for 10 seconds (F and P disc) and 30 seconds (HP disc) respectively. After each polishing step, the surface gloss and roughness were measured with a glossmeter and an optical sensor (FRT MicroProf), respectively. Material loss of the composite specimens and polishing instruments were measured after each step with a high precision digital scale. For all four variables (surface gloss, surface roughness, composite loss, loss of rubber material) the mean percentage of change compared to the reference was calculated. Already after the first use, the instruments which were used without disinfection or sterilization demonstrated a statistically significantly reduced polishing performance in all polishing steps compared to the reference (new polishing system) (t-test, P < 0.05). In addition, this loss in performance further increased with the second and third re-use. Especially the third component (Astropol HP) was affected by performance loss. By contrast, the multiple-use of the instruments which were subjected to prolonged disinfection did not result in a reduced polishing performance. For the P disc, a statistically significant improvement of the polishing performance could be observed throughout almost all multiple-use sessions (ANOVA, P < 0.05). The improved polishing performance was, however, accompanied by an increased loss of the silicone rubber material of the P and F polishing discs; the HP discs were not affected by this loss. Furthermore, particles of the rubber material also adhered to the composite. The polishing performance of the discs which were only subjected to the sterilization process was not statistically significantly different to the polishing performance of the control group in terms of surface roughness; but the surface gloss was worse than that of the control group. No loss of rubber material or adherence to the composite was observed in this group.
Showalter, Brent L.; Beckstein, Jesse C.; Martin, John T.; Beattie, Elizabeth E.; Orías, Alejandro A. Espinoza; Schaer, Thomas P.; Vresilovic, Edward J.; Elliott, Dawn M.
2012-01-01
Study Design Experimental measurement and normalization of in vitro disc torsion mechanics and collagen content for several animal species used in intervertebral disc research and comparing these to the human disc. Objective To aid in the selection of appropriate animal models for disc research by measuring torsional mechanical properties and collagen content. Summary of Background Data There is lack of data and variability in testing protocols for comparing animal and human disc torsion mechanics and collagen content. Methods Intervertebral disc torsion mechanics were measured and normalized by disc height and polar moment of inertia for 11 disc types in 8 mammalian species: the calf, pig, baboon, goat, sheep, rabbit, rat, and mouse lumbar, and cow, rat, and mouse caudal. Collagen content was measured and normalized by dry weight for the same discs except the rat and mouse. Collagen fiber stretch in torsion was calculated using an analytical model. Results Measured torsion parameters varied by several orders of magnitude across the different species. After geometric normalization, only the sheep and pig discs were statistically different from human. Fiber stretch was found to be highly dependent on the assumed initial fiber angle. The collagen content of the discs was similar, especially in the outer annulus where only the calf and goat discs were statistically different from human. Disc collagen content did not correlate with torsion mechanics. Conclusion Disc torsion mechanics are comparable to human lumbar discs in 9 of 11 disc types after normalization by geometry. The normalized torsion mechanics and collagen content of the multiple animal discs presented is useful for selecting and interpreting results for animal models of the disc. Structural composition of the disc, such as initial fiber angle, may explain the differences that were noted between species after geometric normalization. PMID:22333953
Infrared characterization of thermal gradients on disc brakes
NASA Astrophysics Data System (ADS)
Panier, Stephane; Dufrenoy, Philippe; Bremond, Pierre
2003-04-01
The heat generated in frictional organs like brakes and clutches induces thermal distortions which may lead to localized contact areas and hot spots developments. Hot spots are high thermal gradients on the rubbing surface. They count among the most dangerous phenomena in frictional organs leading to damage, early failure and unacceptable braking performances such as brake fade or undesirable low frequency vibrations called hot judder. In this paper, an experimental study of hot spots occurrence in railway disc brakes is reported on. The aim of this study was to better classify and to explain the thermal gradients appearance on the surface of the disc. Thermograph measurements with an infrared camera have been carried out on the rubbing surface of brake discs on a full-scale test bench. The infrared system was set to take temperature readings in snap shot mode precisely synchronized with the rotation of the disc. Very short integration time allows reducing drastically haziness of thermal images. Based on thermographs, a classification of hot-spots observed in disc brakes is proposed. A detailed investigation of the most damaging thermal gradients, called macroscopic hot spots (MHS) is given. From these experimental researches, a scenario of hot spots occurrence is suggested step by step. Thanks to infrared measurements at high frequency with high resolution, observations give new highlights on the conditions of hot spots appearance. Comparison of the experimental observations with the theoretical approaches is finally discussed.
Binary stars in the Galactic thick disc
NASA Astrophysics Data System (ADS)
Izzard, Robert G.; Preece, Holly; Jofre, Paula; Halabi, Ghina M.; Masseron, Thomas; Tout, Christopher A.
2018-01-01
The combination of asteroseismologically measured masses with abundances from detailed analyses of stellar atmospheres challenges our fundamental knowledge of stars and our ability to model them. Ancient red-giant stars in the Galactic thick disc are proving to be most troublesome in this regard. They are older than 5 Gyr, a lifetime corresponding to an initial stellar mass of about 1.2 M⊙. So why do the masses of a sizeable fraction of thick-disc stars exceed 1.3 M⊙, with some as massive as 2.3 M⊙? We answer this question by considering duplicity in the thick-disc stellar population using a binary population-nucleosynthesis model. We examine how mass transfer and merging affect the stellar mass distribution and surface abundances of carbon and nitrogen. We show that a few per cent of thick-disc stars can interact in binary star systems and become more massive than 1.3 M⊙. Of these stars, most are single because they are merged binaries. Some stars more massive than 1.3 M⊙ form in binaries by wind mass transfer. We compare our results to a sample of the APOKASC data set and find reasonable agreement except in the number of these thick-disc stars more massive than 1.3 M⊙. This problem is resolved by the use of a logarithmically flat orbital-period distribution and a large binary fraction.
Leaf shrinkage with dehydration: coordination with hydraulic vulnerability and drought tolerance.
Scoffoni, Christine; Vuong, Christine; Diep, Steven; Cochard, Hervé; Sack, Lawren
2014-04-01
Leaf shrinkage with dehydration has attracted attention for over 100 years, especially as it becomes visibly extreme during drought. However, little has been known of its correlation with physiology. Computer simulations of the leaf hydraulic system showed that a reduction of hydraulic conductance of the mesophyll pathways outside the xylem would cause a strong decline of leaf hydraulic conductance (K(leaf)). For 14 diverse species, we tested the hypothesis that shrinkage during dehydration (i.e. in whole leaf, cell and airspace thickness, and leaf area) is associated with reduction in K(leaf) at declining leaf water potential (Ψ(leaf)). We tested hypotheses for the linkage of leaf shrinkage with structural and physiological water relations parameters, including modulus of elasticity, osmotic pressure at full turgor, turgor loss point (TLP), and cuticular conductance. Species originating from moist habitats showed substantial shrinkage during dehydration before reaching TLP, in contrast with species originating from dry habitats. Across species, the decline of K(leaf) with mild dehydration (i.e. the initial slope of the K(leaf) versus Ψ(leaf) curve) correlated with the decline of leaf thickness (the slope of the leaf thickness versus Ψ(leaf) curve), as expected based on predictions from computer simulations. Leaf thickness shrinkage before TLP correlated across species with lower modulus of elasticity and with less negative osmotic pressure at full turgor, as did leaf area shrinkage between full turgor and oven desiccation. These findings point to a role for leaf shrinkage in hydraulic decline during mild dehydration, with potential impacts on drought adaptation for cells and leaves, influencing plant ecological distributions.
NASA Astrophysics Data System (ADS)
Omel'chenko, A. I.; Sobol', E. N.
2009-03-01
The thermomechanical effect of 1.56-μm fibre laser pulses on intervertebral disc cartilage has been studied using ac conductivity measurements with coaxial electrodes integrated with an optical fibre for laser radiation delivery to the tissue. The observed time dependences of tissue conductivity can be interpreted in terms of hydraulic effects and thermomechanical changes in tissue structure. The laserinduced changes in the electrical parameters of the tissue are shown to correlate with the structural changes, which were visualised using shadowgraph imaging. Local ac conductivity measurements in the bulk of tissue can be used to develop a diagnostic/monitoring system for laser regeneration of intervertebral discs.
McKown, Athena D; Cochard, Hervé; Sack, Lawren
2010-04-01
Leaf venation architecture is tremendously diverse across plant species. Understanding the hydraulic functions of given venation traits can clarify the organization of the vascular system and its adaptation to environment. Using a spatially explicit model (the program K_leaf), we subjected realistic simulated leaves to modifications and calculated the impacts on xylem and leaf hydraulic conductance (K(x) and K(leaf), respectively), important traits in determining photosynthesis and growth. We tested the sensitivity of leaves to altered vein order conductivities (1) in the absence or (2) presence of hierarchical vein architecture, (3) to major vein tapering, and (4) to modification of vein densities (length/leaf area). The K(x) and K(leaf) increased with individual vein order conductivities and densities; for hierarchical venation systems, the greatest impact was from increases in vein conductivity for lower vein orders and increases in density for higher vein orders. Individual vein order conductivities were colimiting of K(x) and K(leaf), as were their densities, but the effects of vein conductivities and densities were orthogonal. Both vein hierarchy and vein tapering increased K(x) relative to xylem construction cost. These results highlight the important consequences of venation traits for the economics, ecology, and evolution of plant transport capacity.
Bars in dark-matter-dominated dwarf galaxy discs
NASA Astrophysics Data System (ADS)
Marasco, A.; Oman, K. A.; Navarro, J. F.; Frenk, C. S.; Oosterloo, T.
2018-05-01
We study the shape and kinematics of simulated dwarf galaxy discs in the APOSTLE suite of Λ cold dark matter (ΛCDM) cosmological hydrodynamical simulations. We find that a large fraction of these gas-rich, star-forming discs show weak bars in their stellar component, despite being dark-matter-dominated systems. The bar pattern shape and orientation reflect the ellipticity of the dark matter potential, and its rotation is locked to the slow figure rotation of the triaxial dark halo. The bar-like nature of the potential induces non-circular motions in the gas component, including strong bisymmetric flows that can be readily seen as m = 3 harmonic perturbations in the H I line-of-sight velocity fields. Similar bisymmetric flows are seen in many galaxies of The HI Nearby Galaxy Survey (THINGS) and Local Irregulars That Trace Luminosity Extremes THINGS (LITTLE THINGS), although on average their amplitudes are a factor of ˜2 weaker than in our simulated discs. Our results indicate that bar-like patterns may arise even when baryons are not dominant, and that they are common enough to warrant careful consideration when analysing the gas kinematics of dwarf galaxy discs.
Automatic detection of retinal anatomy to assist diabetic retinopathy screening.
Fleming, Alan D; Goatman, Keith A; Philip, Sam; Olson, John A; Sharp, Peter F
2007-01-21
Screening programmes for diabetic retinopathy are being introduced in the United Kingdom and elsewhere. These require large numbers of retinal images to be manually graded for the presence of disease. Automation of image grading would have a number of benefits. However, an important prerequisite for automation is the accurate location of the main anatomical features in the image, notably the optic disc and the fovea. The locations of these features are necessary so that lesion significance, image field of view and image clarity can be assessed. This paper describes methods for the robust location of the optic disc and fovea. The elliptical form of the major retinal blood vessels is used to obtain approximate locations, which are refined based on the circular edge of the optic disc and the local darkening at the fovea. The methods have been tested on 1056 sequential images from a retinal screening programme. Positional accuracy was better than 0.5 of a disc diameter in 98.4% of cases for optic disc location, and in 96.5% of cases for fovea location. The methods are sufficiently accurate to form an important and effective component of an automated image grading system for diabetic retinopathy screening.
Experimental Studies of Spray Deposition on a Flat Surface in a Vacuum Environment
NASA Technical Reports Server (NTRS)
Golliher, Eric L.; Yao, S. C.
2015-01-01
Cooling of spacecraft components in the space environment is an on-going research effort. The electronics used in modern spacecraft are always changing and the heat flux is increasing. New, one-of-a-kind missions require new approaches to thermal control. In this research, under vacuum conditions, a pulsed water spray impinged on a small disc, while a high speed data acquisition system recorded the temperature histories of this copper disc. The water droplets froze quickly and accumulated on the disc as the spray continued. After the spray stopped, the frozen water that remained on the disc then sublimated into the vacuum environment and cooled the disc. This paper examines two important aspects of this process: 1) the difference in spray start up and shutdown in a vacuum environment versus in a standard atmospheric pressure environment, and 2) the water utilization efficiency in a vacuum environment due to the effects of drop trajectories and drop bouncing on the surface. Both phenomena play a role during spray cooling in a vacuum. This knowledge should help spacecraft designers plan for spray cooling as an option to cool spacecraft electronics, human metabolic generated heat, and heat from other sources.
The transiting dust clumps in the evolved disc of the Sun-like UXor RZ Psc.
Kennedy, Grant M; Kenworthy, Matthew A; Pepper, Joshua; Rodriguez, Joseph E; Siverd, Robert J; Stassun, Keivan G; Wyatt, Mark C
2017-01-01
RZ Psc is a young Sun-like star, long associated with the UXor class of variable stars, which is partially or wholly dimmed by dust clumps several times each year. The system has a bright and variable infrared excess, which has been interpreted as evidence that the dimming events are the passage of asteroidal fragments in front of the host star. Here, we present a decade of optical photometry of RZ Psc and take a critical look at the asteroid belt interpretation. We show that the distribution of light curve gradients is non-uniform for deep events, which we interpret as possible evidence for an asteroidal fragment-like clump structure. However, the clumps are very likely seen above a high optical depth midplane, so the disc's bulk clumpiness is not revealed. While circumstantial evidence suggests an asteroid belt is more plausible than a gas-rich transition disc, the evolutionary status remains uncertain. We suggest that the rarity of Sun-like stars showing disc-related variability may arise because (i) any accretion streams are transparent and/or (ii) turbulence above the inner rim is normally shadowed by a flared outer disc.
Automatic detection of retinal anatomy to assist diabetic retinopathy screening
NASA Astrophysics Data System (ADS)
Fleming, Alan D.; Goatman, Keith A.; Philip, Sam; Olson, John A.; Sharp, Peter F.
2007-01-01
Screening programmes for diabetic retinopathy are being introduced in the United Kingdom and elsewhere. These require large numbers of retinal images to be manually graded for the presence of disease. Automation of image grading would have a number of benefits. However, an important prerequisite for automation is the accurate location of the main anatomical features in the image, notably the optic disc and the fovea. The locations of these features are necessary so that lesion significance, image field of view and image clarity can be assessed. This paper describes methods for the robust location of the optic disc and fovea. The elliptical form of the major retinal blood vessels is used to obtain approximate locations, which are refined based on the circular edge of the optic disc and the local darkening at the fovea. The methods have been tested on 1056 sequential images from a retinal screening programme. Positional accuracy was better than 0.5 of a disc diameter in 98.4% of cases for optic disc location, and in 96.5% of cases for fovea location. The methods are sufficiently accurate to form an important and effective component of an automated image grading system for diabetic retinopathy screening.
The transiting dust clumps in the evolved disc of the Sun-like UXor RZ Psc
NASA Astrophysics Data System (ADS)
Kennedy, Grant M.; Kenworthy, Matthew A.; Pepper, Joshua; Rodriguez, Joseph E.; Siverd, Robert J.; Stassun, Keivan G.; Wyatt, Mark C.
2017-01-01
RZ Psc is a young Sun-like star, long associated with the UXor class of variable stars, which is partially or wholly dimmed by dust clumps several times each year. The system has a bright and variable infrared excess, which has been interpreted as evidence that the dimming events are the passage of asteroidal fragments in front of the host star. Here, we present a decade of optical photometry of RZ Psc and take a critical look at the asteroid belt interpretation. We show that the distribution of light curve gradients is non-uniform for deep events, which we interpret as possible evidence for an asteroidal fragment-like clump structure. However, the clumps are very likely seen above a high optical depth midplane, so the disc's bulk clumpiness is not revealed. While circumstantial evidence suggests an asteroid belt is more plausible than a gas-rich transition disc, the evolutionary status remains uncertain. We suggest that the rarity of Sun-like stars showing disc-related variability may arise because (i) any accretion streams are transparent and/or (ii) turbulence above the inner rim is normally shadowed by a flared outer disc.
NASA Astrophysics Data System (ADS)
Alonso-Martínez, M.; Riviere-Marichalar, P.; Meeus, G.; Kamp, I.; Fang, M.; Podio, L.; Dent, W. R. F.; Eiroa, C.
2017-07-01
Context. At early stages of stellar evolution young stars show powerful jets and/or outflows that interact with protoplanetary discs and their surroundings. Despite the scarce knowledge about the interaction of jets and/or outflows with discs, spectroscopic studies based on Herschel and ISO data suggests that gas shocked by jets and/or outflows can be traced by far-IR (FIR) emission in certain sources. Aims: We want to provide a consistent catalogue of selected atomic ([OI] and [CII]) and molecular (CO, H2O, and OH) line fluxes observed in the FIR, separate and characterize the contribution from the jet and the disc to the observed line emission, and place the observations in an evolutionary picture. Methods: The atomic and molecular FIR (60-190 μm) line emission of protoplanetary discs around 76 T Tauri stars located in Taurus are analysed. The observations were carried out within the Herschel key programme Gas in Protoplanetary Systems (GASPS). The spectra were obtained with the Photodetector Array Camera and Spectrometer (PACS). The sample is first divided in outflow and non-outflow sources according to literature tabulations. With the aid of archival stellar/disc and jet/outflow tracers and model predictions (PDRs and shocks), correlations are explored to constrain the physical mechanisms behind the observed line emission. Results: Outflow sources exhibit brighter atomic and molecular emission lines and higher detection rates than non-outflow sources. The line detection fractions decrease with SED evolutionary status (from Class I to Class III). We find correlations between [OI] 63.18 μm and [OI] 6300 Å, o-H2O 78.74 μm, CO 144.78 μm, OH 79.12+79.18 μm, and the continuum flux at 24 μm. The atomic line ratios can be explain either by fast (Vshock > 50 km s-1) dissociative J-shocks at low densities (n 103 cm-3) occurring along the jet and/or PDR emission (G0 > 102, n 103-106 cm-3). To account for the [CII] absolute fluxes, PDR emission or UV irradiation of shocks is needed. In comparison, the molecular emission is more compact and the line ratios are better explained with slow (Vshock < 40 km s-1) C-type shocks with high pre-shock densities (104-106 cm-3), with the exception of OH lines, that are better described by J-type shocks. Disc models alone fail to reproduce the observed molecular line fluxes, but a contribution to the line fluxes from UV-illuminated discs and/or outflow cavities is expected. Far-IR lines dominate disc cooling at early stages and weaken as the star+disc system evolves from Class I to Class III, with an increasing relative disc contribution to the line fluxes. Conclusions: Models which take into account jets, discs, and their mutual interaction are needed to disentangle the different components and study their evolution. The much higher detection rate of emission lines in outflow sources and the compatibility of line ratios with shock model predictions supports the idea of a dominant contribution from the jet/outflow to the line emission, in particular at earlier stages of the stellar evolution as the brightness of FIR lines depends in large part on the specific evolutionary stage. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.
Response of Leaf Water Potential, Stomatal Resistance, and Leaf Rolling to Water Stress
O'Toole, John C.; Cruz, Rolando T.
1980-01-01
Numerous studies have associated increased stomatal resistance with response to water deficit in cereals. However, consideration of change in leaf form seems to have been neglected. The response of adaxial and abaxial stomatal resistance and leaf rolling in rice to decreasing leaf water potential was investigated. Two rice cultivars were subjected to control and water stress treatments in a deep (1-meter) aerobic soil. Concurrent measurements of leaf water potential, stomatal resistance, and degree of leaf rolling were made through a 29-day period after cessation of irrigation. Kinandang Patong, an upland adapted cultivar, maintained higher dawn and midday leaf water potential than IR28, a hybrid selected in irrigated conditions. This was not explained by differences in leaf diffusive resistance or leaf rolling, and is assumed to result from a difference in root system extent. Stomatal resistance increased more on the abaxial than the adaxial leaf surface in both cultivars. This was associated with a change in leaf form or rolling inward of the upper leaf surface. Both responses, increased stomatal resistance and leaf rolling, were initiated in a similar leaf water potential range (−8 to −12 bars). Leaves of IR28 became fully rolled at leaf water potential of about −22 bars; however, total leaf diffusive resistance was only about 4 to 5 seconds per centimeter (conductance 0.25 to 0.2 centimeter per second) at that stage. Leaf diffusive resistance and degree of leaf rolling were linearly related to leaf water potential. Thus, leaf rolling in rice may be used as an estimate of the other two less obvious effects of water deficit. PMID:16661206
Weng, Ensheng; Farrior, Caroline E; Dybzinski, Ray; Pacala, Stephen W
2017-06-01
Earth system models are incorporating plant trait diversity into their land components to better predict vegetation dynamics in a changing climate. However, extant plant trait distributions will not allow extrapolations to novel community assemblages in future climates, which will require a mechanistic understanding of the trade-offs that determine trait diversity. In this study, we show how physiological trade-offs involving leaf mass per unit area (LMA), leaf lifespan, leaf nitrogen, and leaf respiration may explain the distribution patterns of evergreen and deciduous trees in the temperate and boreal zones based on (1) an evolutionary analysis of a simple mathematical model and (2) simulation experiments of an individual-based dynamic vegetation model (i.e., LM3-PPA). The evolutionary analysis shows that these leaf traits set up a trade-off between carbon- and nitrogen-use efficiency at the scale of individual trees and therefore determine competitively dominant leaf strategies. As soil nitrogen availability increases, the dominant leaf strategy switches from one that is high in nitrogen-use efficiency to one that is high in carbon-use efficiency or, equivalently, from high-LMA/long-lived leaves (i.e., evergreen) to low-LMA/short-lived leaves (i.e., deciduous). In a region of intermediate soil nitrogen availability, the dominant leaf strategy may be either deciduous or evergreen depending on the initial conditions of plant trait abundance (i.e., founder controlled) due to feedbacks of leaf traits on soil nitrogen mineralization through litter quality. Simulated successional patterns by LM3-PPA from the leaf physiological trade-offs are consistent with observed successional dynamics of evergreen and deciduous forests at three sites spanning the temperate to boreal zones. © 2016 John Wiley & Sons Ltd.
The energetic and carbon economic origins of leaf thermoregulation.
Michaletz, Sean T; Weiser, Michael D; McDowell, Nate G; Zhou, Jizhong; Kaspari, Michael; Helliker, Brent R; Enquist, Brian J
2016-08-22
Leaf thermoregulation has been documented in a handful of studies, but the generality and origins of this pattern are unclear. We suggest that leaf thermoregulation is widespread in both space and time, and originates from the optimization of leaf traits to maximize leaf carbon gain across and within variable environments. Here we use global data for leaf temperatures, traits and photosynthesis to evaluate predictions from a novel theory of thermoregulation that synthesizes energy budget and carbon economics theories. Our results reveal that variation in leaf temperatures and physiological performance are tightly linked to leaf traits and carbon economics. The theory, parameterized with global averaged leaf traits and microclimate, predicts a moderate level of leaf thermoregulation across a broad air temperature gradient. These predictions are supported by independent data for diverse taxa spanning a global air temperature range of ∼60 °C. Moreover, our theory predicts that net carbon assimilation can be maximized by means of a trade-off between leaf thermal stability and photosynthetic stability. This prediction is supported by globally distributed data for leaf thermal and photosynthetic traits. Our results demonstrate that the temperatures of plant tissues, and not just air, are vital to developing more accurate Earth system models.
Cohen, Stephen M.; Jürgens, Gerd
1989-01-01
Limb development in the Drosophila embryo requires a pattern-forming system to organize positional information along the proximal–distal axis of the limb. This system must function in the context of the well characterized anterior–posterior and dorsal–ventral pattern-forming systems that are required to organize the body plan of the embryo. By genetic criteria the Distal-less gene appears to play a central role in limb development. Lack-of-function Distal-less mutations cause the deletion of a specific subset of embryonic peripheral sense organs that represent the evolutionary remnants of larval limbs. Distal-less activity is also required in the imaginal discs for the development of adult limbs. This requirement is cell autonomous and region specific within the developing limb primordium. Production of genetically mosaic imaginal discs, in which clones of cells lack Distal-less activity, indicates the existence of an organized proximal–distal positional information in very young imaginal disc primordia. We suggest that this graded positional information may depend on the activity of the Distal-less gene. Images PMID:16453891
NASA Technical Reports Server (NTRS)
Hall, Philip; Balakumar, P.
1990-01-01
A class of exact steady and unsteady solutions of the Navier Stokes equations in cylindrical polar coordinates is given. The flows correspond to the motion induced by an infinite disc rotating with constant angular velocity about the z-axis in a fluid occupying a semi-infinite region which, at large distances from the disc, has velocity field proportional to (x,-y,O) with respect to a Cartesian coordinate system. It is shown that when the rate of rotation is large, Karman's exact solution for a disc rotating in an otherwise motionless fluid is recovered. In the limit of zero rotation rate a particular form of Howarth's exact solution for three-dimensional stagnation point flow is obtained. The unsteady form of the partial differential system describing this class of flow may be generalized to time-periodic equilibrium flows. In addition the unsteady equations are shown to describe a strongly nonlinear instability of Karman's rotating disc flow. It is shown that sufficiently large perturbations lead to a finite time breakdown of that flow whilst smaller disturbances decay to zero. If the stagnation point flow at infinity is sufficiently strong, the steady basic states become linearly unstable. In fact there is then a continuous spectrum of unstable eigenvalues of the stability equations but, if the initial value problem is considered, it is found that, at large values of time, the continuous spectrum leads to a velocity field growing exponentially in time with an amplitude decaying algebraically in time.
Pick, Thea R; Bräutigam, Andrea; Schlüter, Urte; Denton, Alisandra K; Colmsee, Christian; Scholz, Uwe; Fahnenstich, Holger; Pieruschka, Roland; Rascher, Uwe; Sonnewald, Uwe; Weber, Andreas P M
2011-12-01
We systematically analyzed a developmental gradient of the third maize (Zea mays) leaf from the point of emergence into the light to the tip in 10 continuous leaf slices to study organ development and physiological and biochemical functions. Transcriptome analysis, oxygen sensitivity of photosynthesis, and photosynthetic rate measurements showed that the maize leaf undergoes a sink-to-source transition without an intermediate phase of C(3) photosynthesis or operation of a photorespiratory carbon pump. Metabolome and transcriptome analysis, chlorophyll and protein measurements, as well as dry weight determination, showed continuous gradients for all analyzed items. The absence of binary on-off switches and regulons pointed to a morphogradient along the leaf as the determining factor of developmental stage. Analysis of transcription factors for differential expression along the leaf gradient defined a list of putative regulators orchestrating the sink-to-source transition and establishment of C(4) photosynthesis. Finally, transcriptome and metabolome analysis, as well as enzyme activity measurements, and absolute quantification of selected metabolites revised the current model of maize C(4) photosynthesis. All data sets are included within the publication to serve as a resource for maize leaf systems biology.
Pick, Thea R.; Bräutigam, Andrea; Schlüter, Urte; Denton, Alisandra K.; Colmsee, Christian; Scholz, Uwe; Fahnenstich, Holger; Pieruschka, Roland; Rascher, Uwe; Sonnewald, Uwe; Weber, Andreas P.M.
2011-01-01
We systematically analyzed a developmental gradient of the third maize (Zea mays) leaf from the point of emergence into the light to the tip in 10 continuous leaf slices to study organ development and physiological and biochemical functions. Transcriptome analysis, oxygen sensitivity of photosynthesis, and photosynthetic rate measurements showed that the maize leaf undergoes a sink-to-source transition without an intermediate phase of C3 photosynthesis or operation of a photorespiratory carbon pump. Metabolome and transcriptome analysis, chlorophyll and protein measurements, as well as dry weight determination, showed continuous gradients for all analyzed items. The absence of binary on–off switches and regulons pointed to a morphogradient along the leaf as the determining factor of developmental stage. Analysis of transcription factors for differential expression along the leaf gradient defined a list of putative regulators orchestrating the sink-to-source transition and establishment of C4 photosynthesis. Finally, transcriptome and metabolome analysis, as well as enzyme activity measurements, and absolute quantification of selected metabolites revised the current model of maize C4 photosynthesis. All data sets are included within the publication to serve as a resource for maize leaf systems biology. PMID:22186372
NASA Astrophysics Data System (ADS)
Mayes, M. T.; Estes, L. D.; Gago, X.; Debats, S. R.; Caylor, K. K.; Manfreda, S.; Oudemans, P.; Ciraolo, G.; Maltese, A.; Nadal, M.; Estrany, J.
2016-12-01
Leaf area is an important ecosystem variable that relates to vegetation biomass, productivity, water and nutrient use in natural and agricultural systems globally. Since the 1980s, optical satellite image-based estimates of leaf area based on indices such as Normalized Difference Vegetation Index (NDVI) have greatly improved understanding of vegetation structure, function, and responses to disturbance at landscape (10^3 km2) to continental (10^6 km2) spatial scales. However, at landscape scales, satellites have failed to capture many leaf area patterns indicative of vegetation succession, crop types, stress and other conditions important for ecological processes. Small drones (UAS - unmanned aerial systems) offer new means for assessing leaf area and vegetation structure at higher spatial resolutions (<1 m) and land cover features such as substrate exposure that may affect estimates of vegetation structure in satellite data. Yet it is unclear how differences in spatial and spectral resolution between UAS and satellite data affect their relationships to each other, and to common field measurements of leaf area (e.g. LiCOR photosensors) and land cover. Constraining these relationships is important for leveraging UAS data to improve scaling of field data on leaf area and biomass to satellite data from Landsat, Sentinel-2, and increasing numbers of commercial sensors. Here, we quantify relationships among field, UAS and satellite estimates of vegetation leaf area and biomass in three case study landscapes spanning semi-arid Mediterranean (Matera, Southern Italy and Mallorca, Spain) and North American temperate ecosystems (New Jersey, USA). We assess how land cover and sensor spectral characteristics affect UAS and satellite-derived NDVI, leaf-area and biomass estimates. Then, we assess the fidelity of UAS, WorldView-2, and Landsat leaf-area and biomass estimates to field-measured landscape changes and variability, including vegetation recovery from fire (Mallorca), and leaf-area and biomass variability due to orchard type and agro-ecosystem management (Matera, New Jersey). Finally, we highlight promising ways forward for improving field data collection and the use of UAS observations to monitor vegetation leaf-area and biomass change at landscape scales in natural and agricultural systems.
Intelligent Tutoring Systems: Machine Learning Research
1991-07-01
is composed of cutin . Ki: Cutin is impermeable to gases. Does the cuticle restrict water loss from the leaf? Domain Expert: Yes, that’s right. Kl...transported from inside the Leaf Epidermis to the atmosphere outside of the Leaf Epidermis. Rule 1: If an object is composed of cutin , then it is
Large Steel Tank Fails and Rockets to Height of 30 meters - Rupture Disc Installed Incorrectly.
Hedlund, Frank H; Selig, Robert S; Kragh, Eva K
2016-06-01
At a brewery, the base plate-to-shell weld seam of a 90-m(3) vertical cylindrical steel tank failed catastrophically. The 4 ton tank "took off" like a rocket leaving its contents behind, and landed on a van, crushing it. The top of the tank reached a height of 30 m. The internal overpressure responsible for the failure was an estimated 60 kPa. A rupture disc rated at < 50 kPa provided overpressure protection and thus prevented the tank from being covered by the European Pressure Equipment Directive. This safeguard failed and it was later discovered that the rupture disc had been installed upside down. The organizational root cause of this incident may be a fundamental lack of appreciation of the hazards of large volumes of low-pressure compressed air or gas. A contributing factor may be that the standard piping and instrumentation diagram (P&ID) symbol for a rupture disc may confuse and lead to incorrect installation. Compressed air systems are ubiquitous. The medium is not toxic or flammable. Such systems however, when operated at "slight overpressure" can store a great deal of energy and thus constitute a hazard that ought to be addressed by safety managers.
Electromagnetic versus Lense-Thirring alignment of black hole accretion discs
NASA Astrophysics Data System (ADS)
Polko, Peter; McKinney, Jonathan C.
2017-01-01
Accretion discs and black holes (BHs) have angular momenta that are generally misaligned, which can lead to warped discs and bends in any jets produced. We examine whether a disc that is misaligned at large radii can be aligned more efficiently by the torque of a Blandford-Znajek (BZ) jet than by Lense-Thirring (LT) precession. To obtain a strong result, we will assume that these torques maximally align the disc, rather than cause precession, or disc tearing. We consider several disc states that include radiatively inefficient thick discs, radiatively efficient thin discs, and super-Eddington accretion discs. The magnetic field strength of the BZ jet is chosen as either from standard equipartition arguments or from magnetically arrested disc (MAD) simulations. We show that standard thin accretion discs can reach spin-disc alignment out to large radii long before LT would play a role, due to the slow infall time that gives even a weak BZ jet time to align the disc. We show that geometrically thick radiatively inefficient discs and super-Eddington discs in the MAD state reach spin-disc alignment near the BH when density profiles are shallow as in magnetohydrodynamical simulations, while the BZ jet aligns discs with steep density profiles (as in advection-dominated accretion flows) out to larger radii. Our results imply that the BZ jet torque should affect the cosmological evolution of BH spin magnitude and direction, spin measurements in active galactic nuclei and X-ray binaries, and the interpretations for Event Horizon Telescope observations of discs or jets in strong-field gravity regimes.
Rossatto, Davi Rodrigo; Franco, Augusto Cesar
2017-04-01
The assessment of leaf strategies has been a common theme in ecology, especially where multiple sources of environmental constraints (fire, seasonal drought, nutrient-poor soils) impose a strong selection pressure towards leaf functional diversity, leading to inevitable tradeoffs among leaf traits, and ultimately to niche segregation among coexisting species. As diversification on leaf functional strategies is dependent on integration at whole plant level, we hypothesized that regardless of phylogenetic relatedness, leaf trait functional syndromes in a multivariate space would be associated with the type of growth form. We measured traits related to leaf gas exchange, structure and nutrient status in 57 coexisting species encompassing all Angiosperms major clades, in a wide array of plant morphologies (trees, shrubs, sub-shrubs, herbs, grasses and palms) in a savanna of Central Brazil. Growth forms differed in mean values for the studied functional leaf traits. We extracted 4 groups of functional typologies: grasses (elevated leaf dark respiration, light-saturated photosynthesis on a leaf mass and area basis, lower values of leaf Ca and Mg), herbs (high values of SLA, leaf N and leaf Fe), palms (high values of stomatal conductance, leaf transpiration and leaf K) and woody eudicots (sub-shrubs, shrubs and trees; low SLA and high leaf Ca and Mg). Despite the large range of variation among species for each individual trait and the independent evolutionary trajectory of individual species, growth forms were strongly associated with particular leaf trait combinations, suggesting clear evolutionary constraints on leaf function for morphologically similar species in savanna ecosystems.
Mayaud, L; Congedo, M; Van Laghenhove, A; Orlikowski, D; Figère, M; Azabou, E; Cheliout-Heraut, F
2013-10-01
A brain-computer interface aims at restoring communication and control in severely disabled people by identification and classification of EEG features such as event-related potentials (ERPs). The aim of this study is to compare different modalities of EEG recording for extraction of ERPs. The first comparison evaluates the performance of six disc electrodes with that of the EMOTIV headset, while the second evaluates three different electrode types (disc, needle, and large squared electrode). Ten healthy volunteers gave informed consent and were randomized to try the traditional EEG system (six disc electrodes with gel and skin preparation) or the EMOTIV Headset first. Together with the six disc electrodes, a needle and a square electrode of larger surface were simultaneously recording near lead Cz. Each modality was evaluated over three sessions of auditory P300 separated by one hour. No statically significant effect was found for the electrode type, nor was the interaction between electrode type and session number. There was no statistically significant difference of performance between the EMOTIV and the six traditional EEG disc electrodes, although there was a trend showing worse performance of the EMOTIV headset. However, the modality-session interaction was highly significant (P<0.001) showing that, while the performance of the six disc electrodes stay constant over sessions, the performance of the EMOTIV headset drops dramatically between 2 and 3h of use. Finally, the evaluation of comfort by participants revealed an increasing discomfort with the EMOTIV headset starting with the second hour of use. Our study does not recommend the use of one modality over another based on performance but suggests the choice should be made on more practical considerations such as the expected length of use, the availability of skilled labor for system setup and above all, the patient comfort. Copyright © 2013 Elsevier Masson SAS. All rights reserved.
NASA Astrophysics Data System (ADS)
Vollmer, B.; Ostrenga, D.; Johnson, J. E.; Savtchenko, A. K.; Shen, S.; Teng, W. L.; Wei, J. C.
2013-12-01
Digital Object Identifiers (DOIs) are applied to selected data sets at the NASA Goddard Earth Sciences Data and Information Services Center (GES DISC). The DOI system provides an Internet resolution service for unique and persistent identifiers of digital objects. Products assigned DOIs include data from the NASA MEaSUREs Program, the Earth Observing System (EOS) Aqua Atmospheric Infrared Sounder (AIRS) and EOS Aura High Resolution Dynamics Limb Sounder (HIRDLS). DOIs are acquired and registered through EZID, California Digital Library and DataCite. GES DISC hosts a data set landing page associated with each DOI containing information on and access to the data including a recommended data citation when using the product in research or applications. This work includes participation with the earth science community (e.g., Earth Science Information Partners (ESIP) Federation) and the NASA Earth Science Data and Information System (ESDIS) Project to identify, establish and implement best practices for assigning DOIs and managing supporting information, including metadata, for earth science data sets. Future work includes (1) coordination with NASA mission Science Teams and other data providers on the assignment of DOIs for other GES DISC data holdings, particularly for future missions such as Orbiting Carbon Observatory -2 and -3 (OCO-2, OCO-3) and projects (MEaSUREs 2012), (2) construction of landing pages that are both human and machine readable, and (3) pursuing the linking of data and publications with tools such as the Thomson Reuters Data Citation Index.
Hu, Jonathan K.; Morishita, Yuichiro; Montgomery, Scott R.; Hymanson, Henry; Taghavi, Cyrus E.; Do, Duc; Wang, Jeff C.
2011-01-01
Degenerative disc disease and disc bulge in the lumbar spine are common sources of lower back pain. Little is known regarding disc bulge migration and lumbar segmental mobility as the lumbar spine moves from flexion to extension. In this study, 329 symptomatic (low back pain with or without neurological symptoms) patients with an average age of 43.5 years with varying degrees of disc degeneration were examined to characterize the kinematics of the lumbar intervertebral discs through flexion, neutral, and extension weight-bearing positions. In this population, disc bulge migration associated with dynamic motion of the lumbar spine significantly increased with increased grade of disk degeneration. Although no obvious trends relating the migration of disc bulge and angular segmental mobility were seen, translational segmental mobility tended to increase with disc bulge migration in all of the degenerative disc states. It appears that many factors, both static (intervertebral disc degeneration or disc height) and dynamic (lumbar segmental mobility), affect the mechanisms of lumbar disc bulge migration. PMID:24353937
Classifying and modelling spiral structures in hydrodynamic simulations of astrophysical discs
NASA Astrophysics Data System (ADS)
Forgan, D. H.; Ramón-Fox, F. G.; Bonnell, I. A.
2018-05-01
We demonstrate numerical techniques for automatic identification of individual spiral arms in hydrodynamic simulations of astrophysical discs. Building on our earlier work, which used tensor classification to identify regions that were `spiral-like', we can now obtain fits to spirals for individual arm elements. We show this process can even detect spirals in relatively flocculent spiral patterns, but the resulting fits to logarithmic `grand-design' spirals are less robust. Our methods not only permit the estimation of pitch angles, but also direct measurements of the spiral arm width and pattern speed. In principle, our techniques will allow the tracking of material as it passes through an arm. Our demonstration uses smoothed particle hydrodynamics simulations, but we stress that the method is suitable for any finite-element hydrodynamics system. We anticipate our techniques will be essential to studies of star formation in disc galaxies, and attempts to find the origin of recently observed spiral structure in protostellar discs.
Fardon, David F; Williams, Alan L; Dohring, Edward J; Murtagh, F Reed; Gabriel Rothman, Stephen L; Sze, Gordon K
2014-11-15
This article comprises a review of the literature pertaining to the normal and pathological lumbar disc and the compilation of a standardized nomenclature. To provide a resource that promotes a clear understanding of lumbar disc terminology among clinicians, radiologists, and researchers. The article "Nomenclature and Classification of Lumbar Disc Pathology. Recommendations of the Combined Task Forces of the North American Spine Society, American Society of Spine Radiology and American Society of Neuroradiology" was published in 2001 in Spine © Lippincott, Williams and Wilkins and formally endorsed by the 3 boards. Its purpose, which it served for well over a decade, was to promote greater clarity and consistency of usage of spine terminology. Since 2001, there has been sufficient evolution in our understanding of the lumbar disc to suggest the need for revision and updating. The document represents the consensus recommendations of the current combined task forces and reflects changes consistent with current concepts in radiological and clinical care. A PubMed search was performed for literature pertaining to the lumbar disc. The task force members individually and collectively reviewed the literature and revised the 2001 document. It was then reviewed by the governing boards of the American Society of Spine Radiology, the American Society of Neuroradiology, and the North American Spine Society. After further revision based on their feedback, the paper was approved for publication. The article provides a discussion of the recommended diagnostic categories and a glossary of terms pertaining to the lumbar disc, a detailed discussion of the terms and their recommended usage, as well as updated illustrations and literature references. We have revised and updated a document that, since 2001, has provided a widely accepted nomenclature that helps maintain consistency and accuracy in the description of the properties of the normal and abnormal lumbar discs and that serves as a system for classification and reporting built upon that nomenclature.
Propeller-driven outflows from an MRI disc
NASA Astrophysics Data System (ADS)
Lii, Patrick S.; Romanova, Marina M.; Ustyugova, Galina V.; Koldoba, Alexander V.; Lovelace, Richard V. E.
2014-06-01
Accreting magnetized stars may be in the propeller regime of disc accretion in which the angular velocity of the stellar magnetosphere exceeds that of the inner disc. In these systems, the stellar magnetosphere acts as a centrifugal barrier and plays a dominant role in the inner disc dynamics by inhibiting matter accretion on to the star. In this work, we investigate the dynamics of the propeller regime using axisymmetric MHD simulations of MRI-driven accretion on to a rapidly rotating magnetized star. The disc matter is inhibited from accreting on to the star and instead accumulates at the disc-magnetosphere boundary, slowly building up a reservoir of matter. Some of this matter diffuses into the outer magnetosphere where it picks up angular momentum and is ejected as an outflow which gradually collimates at larger distances from the star. If the ejection rate is smaller than the disc's accretion rate, then the matter accumulates at the disc-magnetosphere boundary faster than it can be ejected. In this situation, accretion on to the propelling star proceeds through the episodic accretion cycle in which episodes of matter accumulation are followed by a brief episode of simultaneous ejection and accretion on to the star. In addition to the matter-dominated wind component, the propeller also drives a well-collimated, magnetically dominated Poynting jet which transports energy and angular momentum away from the star. The propelling stars undergo strong spin-down due to the outflow of angular momentum in the wind and jet. We measure spin-down time-scales of ˜1.2 Myr for a cTTs in the strong propeller regime of accretion. The propeller mechanism may explain some of the jets and winds observed around some T Tauri stars as well as the nature of their ejections. It may also explain some of the quasi-periodic variability observed in cataclysmic variables, millisecond pulsars and other magnetized stars.
Wu, W J; Zhang, X K; Zheng, X F; Yang, Y H; Jiang, S D; Jiang, L S
2013-01-01
Hypoxia-inducible factor-1alpha (HIF-1 alpha) has been reported to have an important role in the metabolism and synthesis of extracellular matrix of the nucleus pulposus cells (NPCs) and was assumed to be involved in the process of intervertebral disc degeneration. The objective of this study was to investigate the role of HIF-1alpha in disc degeneration in vivo using a conditional HIF-1alpha knockout (KO) mouse model. ShhCre transgenic mice were mated with HIF-1 alpha fl/fl mice to generate conditional HIF-1alpha KO mice (HIF-1alpha fl/fl-ShhCre+). Three mice of each genotype (Wide-type and HIF-1alpha KO) at the age of 3 days, 6, and 12 weeks were sacrificed after genotyping. Five lumbar disc samples were harvested from each mouse, with a total of 45 disc samples for each genotype. In situ hybridization and immunohistochemical analysis were used to check the efficacy of HIF-1alpha knockout. Histological grading of the disc degeneration was performed according to the classification system proposed by Boos et al. Picro-sirius red staining, Safranine O/fast green staining and immunohistochemical study were used to evaluate the expression of aggrecan, type-II collagen and vascular endothelial growth factor (VEGF). Histologic analysis revealed more NPC deaths and signs of degeneration in HIF-1alpha KO mice and the degeneration scores of HIF-1alpha KO mice were significantly higher than those of the Wide-type mice at the age of 6 weeks and 12 weeks. There were less expressions of aggrecan, type-II collagen and VEGF in the intervertebral discs of HIF1-alpha KO mice than in those of wild-type mice. Taken together, the results of our study indicated that HIF-1alpha is a pivotal contributor to NPC survival and the homeotasis of extracellular matrix through the HIF-1alpha/VEGF signaling pathway, and plays an important role in the development of disc degeneration.