Constancy and Variability: Dialogic Literacy Events as Sites for Improvisation in Two 3rd-Grade Classrooms

ERIC Educational Resources Information Center

Jordan, Michelle E.; Santori, Diane

2015-01-01

This multisite study investigates dialogic literacy events that revolved around narrative and informational texts in two 3rd-grade classrooms. The authors offer a metaphor of musical improvisation to contemplate dialogic literacy events as part of the repertoire of teaching and learning experiences. In literacy learning, where there is much…

More States Retaining 3rd Graders

ERIC Educational Resources Information Center

Robelen, Erik W.

2012-01-01

As increasing numbers of states move to end social promotion of 3rd graders, some are also including interventions to help students learn to read. Oklahoma is one of several states that recently adopted new reading policies that--with limited exceptions--call for 3rd graders to be held back if they flunk a state standardized test. Supporters say…

Promoting learning transfer in post registration education: a collaborative approach.

PubMed

Finn, Frances L; Fensom, Sue A; Chesser-Smyth, Patricia

2010-01-01

Pre-registration nurse education in Ireland became a four year undergraduate honors degree programme in 2002 (Government of Ireland, 2000. The Nursing Education Forum Report. Dublin, Dublin Stationary Office.). Consequently, the Irish Government invested significant resources in post registration nursing education in order to align certificate and diploma trained nurses with the qualification levels of new graduates. However, a general concern amongst academic and clinical staff in the South East of Ireland was that there was limited impact of this initiative on practice. These concerns were addressed through a collaborative approach to the development and implementation of a new part-time post registration degree that incorporated an enquiry and practice based learning philosophy. The principles of learning transfer (Ford, K., 1994. Defining transfer of learning the meaning is in the answers. Adult Learning 5 (4), p. 2214.) underpinned the curriculum development and implementation process with the goal of reducing the theory practice gap. This paper reports on all four stages of the curriculum development process: exploration, design, implementation and evaluation (Quinn, F.M., 2002. Principles and Practices of Nurse Education, fourth ed. Nelson Thornes, Cheltenham), and the subsequent impact of learning transfer on practice development. Eclectic approaches of quantitative and qualitative data collection techniques were utilised in the evaluation. The evaluation of this project to date supports our view that this practice based enquiry curriculum promotes the transfer of learning in the application of knowledge to practice, impacting both student and service development.

Learning to Be an Information Architect

ERIC Educational Resources Information Center

Wusteman, Judith

2013-01-01

This article describes a recently introduced module at University College Dublin School of Information and Library Studies (SILS), entitled "Information Architecture: Designing the Web." The module provides students with a realistic experience of how information architects apply their skills to produce usable web sites, via a project to…

Teaching Newton's 3rd law of motion using learning by design approach

NASA Astrophysics Data System (ADS)

Aquino, Jiezel G.; Caliguid, Mariel P.; Buan, Amelia T.; Magsayod, Joy R.; Lahoylahoy, Myrna E.

2018-01-01

This paper presents the process and implementation of Learning by Design Approach in teaching Newton's 3rd Law of Motion. A lesson activity from integrative STEM education was adapted, modified and enhanced through pilot testing. After revisions, the implementation was done to one class. The respondent's prior knowledge was first assessed by a pretest. PPIT (present the scenario, plan, implement and test) was the framework followed in the implementation of Learning by Design. Worksheets were then utilized to measure their conceptual understanding and perception. A score guide was also used to evaluate the student's output. Paired t-test analysis showed that there is a significant difference in the pretest and posttest achievement scores. This implies that the performance of the students have improved during the implementation of the Learning by Design. The Analysis of variance also depicts that the low, average and high benefited in the Learning by Design approach. The results of this study suggests that Learning by Design is an effective approach in teaching Newton's 3rd Law of Motion and thus be used in a Science classroom.

Disability Awareness and University Staff Training in Ireland (Practice Brief)

ERIC Educational Resources Information Center

Padden, Lisa; Ellis, Carol

2015-01-01

It is vital that all university staff have awareness of the difficulties that may be experienced by students with disabilities. Staff must be given the knowledge and resources to support these students effectively. University College Dublin (UCD) Access & Lifelong Learning has developed a communication and training strategy to improve…

PreK-3rd: How Superintendents Lead Change. PreK-3rd Policy Action Brief. No. Five

ERIC Educational Resources Information Center

Marietta, Geoff

2010-01-01

Leading change to create an integrated PreK-3rd education and connect early learning programs with the K-12 system is not easy. Superintendents require courage to take the first step, persistence and political skills to encourage organizational and community engagement, and a relentless focus on results to measure progress and build momentum. As a…

Implementing Engineering With Nature within the Corps: A Workshop

DTIC Science & Technology

2013-09-01

Browne , University College Dublin 10:55 – 11:25 Breakwaters for the creation of...Kelsie USACE‐ERDC Banks, Cynthia USACE‐ERDC Bowers, Keith Biohabitats Bridges, Todd USACE‐ERDC Browne , Mark University College of Dublin Carter... Browne IRCSET Post‐doctoral Fellow University College Dublin School of Biology and Environmental Sciences Science Centre West Belfield Dublin

Supporting Children's Participation in Second-Language Stories in an Irish-Language Preschool

ERIC Educational Resources Information Center

Mhathuna, Maire Mhic

2008-01-01

This paper considers how children learning a second language were supported as active participants during storytelling sessions in an Irish-language immersion preschool in Dublin. Audio-recordings and observations were made of the story sessions once a fortnight over a period of six months. The resulting transcripts were analysed from an…

Quality Assurance and Teacher Education: International Challenges and Expectations. Rethinking Education. Volume 6

ERIC Educational Resources Information Center

Harford, Judith, Ed.; Hudson, Brian, Ed.; Niemi, Hannele, Ed.

2012-01-01

Ensuring quality in and through teaching and learning has become a fundamental global concern. Emanating from a colloquium on "Quality Assurance and Teacher Education" hosted by University College Dublin in 2010 and funded by the European Educational Research Association, this book interrogates how quality cultures can be fostered in the…

Lecturer Responses to the Inclusion of Students with Intellectual Disabilities Auditing Undergraduate Classes

ERIC Educational Resources Information Center

O'Connor, Barrie; Kubiak, John; Espiner, Deborah; O'Brien, Patricia

2012-01-01

Although postsecondary education for people with intellectual disabilities can improve their chances of employment and create a more satisfying life, higher education is becoming a more usual avenue of postschool learning. As part of a 2-year Certificate in Contemporary Living (CCL) Program offered at Trinity College Dublin, students audited…

Emerging Trends and New Directions in Telecollaborative Learning

ERIC Educational Resources Information Center

O'Dowd, Robert

2016-01-01

This article provides an overview of the most significant emerging trends and tendencies in telecollaborative practice. In order to achieve this, I review the recent literature in the area and I identify recurring themes from the Telecollaboration in Higher Education conference which took place in Trinity College Dublin, Ireland from 21 to 23…

Proceedings of the International Association for Development of the Information Society (IADIS) International Conference on Cognition and Exploratory Learning in the Digital Age (CELDA) (12th, Maynooth, Greater Dublin, Ireland, October 24-26, 2015)

ERIC Educational Resources Information Center

Sampson, Demetrios G., Ed.; Spector, J. Michael, Ed.; Ifenthaler, Dirk, Ed.; Isaias, Pedro, Ed.

2015-01-01

These proceedings contain the papers of the 12th International Conference on Cognition and Exploratory Learning in the Digital Age (CELDA 2015), October 24-26, 2015, which has been organized by the International Association for Development of the Information Society (IADIS), co-organized by Maynooth University, Ireland, and endorsed by the…

Sir Patrick Dun and the Complete School of Physic in eighteenth-century Dublin.

PubMed

Mullaney, S

2015-03-01

2013 is the tercentenary of the death of Sir Patrick Dun. When Dun died in 1713, he left the proceeds of his estate to enhance medical education in Dublin by funding chairs in medicine. He showed remarkable innovation, but it took 95 years, five Acts of Parliament, two House of Commons enquiries and a House of Lords enquiry before Dun's wishes were brought to fruition and systematic clinical education was available for Dublin medical students. The passage of the final School of Physic Act in 1800 insured that a hospital would open in his name and regular clinical education was provided. The physician, Richard Steevens, who died 3 years earlier in 1710, left the proceeds of his estate to found a hospital, which opened, in his name, in 1733. The contemporary primary sources have been analysed and material from relevant secondary sources has been included where appropriate. Dublin was the beneficiary of these bequests and if circumstances had been more favourable, and the proceeds had been used more efficiently at the start of the eighteenth-century, Dublin could well have rivalled Edinburgh as the seat of medical education in the eighteenth century. In the early nineteenth century, it would fulfil that role and equal Edinburgh as one of the primary centres of medical education in Europe.

Prevalence of culturable airborne spores of selected allergenic and pathogenic fungi in outdoor air

NASA Astrophysics Data System (ADS)

O'Gorman, Céline M.; Fuller, Hubert T.

2008-06-01

Temporal and spatial variations in airborne spore concentrations of selected allergenic and pathogenic fungi were examined in Dublin, Ireland, in 2005. Air samples were taken at four outdoor locations in the city every 2 weeks, coupled with measurements of meteorological conditions. Total culturable airborne fungal spore concentrations in Dublin ranged from 30-6800 colony forming units per cubic metre of air (CFU m-3) over the 12-month period. Cladosporium, Penicillium, Aspergillus and Alternaria spores were constantly present in the Dublin atmosphere, representing >20% of the total culturable spore count. Concentrations of Cladosporium increased significantly in summer and reached allergenic threshold levels, peaking at over 3200 CFU m-3 in August. Penicillium spore concentrations never reached allergenic threshold levels, with average concentrations of <150 CFU m-3. Alternaria conidia formed only 0.3% of the total culturable fungal spore count and concentrations never exceeded 50 CFU m-3, attributable to the coastal position of Dublin and its low levels of arable production. The opportunistic human pathogen Aspergillus fumigatus was present throughout the year in nominal concentrations (<10 CFU m-3), but sporadic high counts were also recorded (300-400 CFU m-3), the potential health implications of which give cause for concern. Spores of neither Cryptococcus neoformans nor Stachybotrys chartarum were detected, but airborne basidiospores of Schizophyllum commune were evidenced by the dikaryotization of monokaryon tester strains following exposure to the air. The relationships between airborne fungal spore concentrations and meteorological factors were analysed by redundancy analysis and revealed positive correlations between temperature and Cladosporium and relative humidity and Penicillium and Aspergillus.

A comparison of dental caries levels in two communities with different oral health prevention strategies stratified in different social classes.

PubMed

Sagheri, Darius; McLoughlin, Jacinta; Clarkson, John J

2007-01-01

To compare dental caries levels of schoolchildren stratified in different social classes whose domestic water supply had been fluoridated since birth (Dublin) with those living in an area where fluoridated salt was available (Freiburg). A representative, random sample of twelve-year-old children was examined and dental caries was recorded using World Health Organization criteria. A total of 699 twelve-year-old children were examined, 377 were children in Dublin and 322 in Freiburg. In Dublin the mean decayed, missing, and filled permanent teeth (DMFT) was 0.80 and in Freiburg it was 0.69. An examination of the distribution of the DMFT score revealed that its distribution is highly positively skewed. For this reason this study provides summary analyses based on medians and inter-quartile range and nonparametric rank sum tests. In both cities caries levels of children in social class 1 (highest) were considerably lower when compared with the other social classes regardless of the fluoride intervention model used. The caries levels showed a reduced disparity between children in social class 2 (medium) and 3 (lowest) in Dublin compared with those in social class 2 and 3 in Freiburg. The evidence from this study confirmed that water fluoridation has reduced the gap in dental caries experience between medium and lower social classes in Dublin compared with the greater difference in caries experience between the equivalent social classes in Freiburg. The results from this study established the important role of salt fluoridation where water fluoridation is not feasible.

Universal Design for Learning and Its Application to Clinical Placements in Health Science Courses (Practice Brief)

ERIC Educational Resources Information Center

Heelan, Ann; Halligan, Phil; Quirke, Mary

2015-01-01

In 2013 Ireland's Association for Higher Education, Access and Disability (AHEAD), in partnership with the School of Nursing University College Dublin (UCD), hosted a summer school for professionals working in the Health Sciences sector who have responsibility for including students with disabilities in the health professions, including clinical…

Report from the European Prison Education Association, September 2007

ERIC Educational Resources Information Center

Behan, Cormac

2007-01-01

The main activity of the European Prison Education Association (EPEA) since the last edition of the Journal was the 11th European Prison Education Association International Conference, which took place in Dublin, Ireland from June 13th to 17th. The conference, Learning for Liberation, was the largest EPEA conference to date with 180 participants…

Integrating Personal Development and Career Planning: The Outcomes for First Year Undergraduate Learning

ERIC Educational Resources Information Center

Monks, Kathy; Conway, Edel; Dhuigneain, Muireann Ni

2006-01-01

This article describes the way in which colleagues from the Business faculty, the Careers Service and the Library at Dublin City University collaborated to design and deliver an integrated approach to personal development planning (PDP) with the aim of motivating first year undergraduate students to take greater responsibility for their own…

DUBLIN CORE

EPA Science Inventory

The Dublin Core is a metadata element set intended to facilitate discovery of electronic resources. It was originally conceived for author-generated descriptions of Web resources, and the Dublin Core has attracted broad ranging international and interdisciplinary support. The cha...

The Salmonella dublin virulence plasmid mediates systemic but not enteric phases of salmonellosis in cattle.

PubMed Central

Wallis, T S; Paulin, S M; Plested, J S; Watson, P R; Jones, P W

1995-01-01

Plasmid-bearing and plasmid-free isolates and a plasmid-cured strain of Salmonella dublin were compared for virulence in calves. The plasmid-bearing strains were highly virulent, causing severe enteric and systemic disease with high mortality. In contrast, the plasmid-free strains caused diarrhea but only low mortality. The infection kinetics of a wild-type and a derivative plasmid-cured strain were compared. Both strains were isolated in high numbers from intestinal sites at 3 and 6 days after oral challenge and were isolated at comparable frequencies from systemic sites at 3 days, but not at 6 days, when the wild-type strain was predominant. The strains were equally invasive in intestinal epithelia with and without Peyer's patch and elicited comparable secretory and inflammatory responses and intestinal pathology in ligated ileal loops. The effect of the virulence plasmid on growth kinetics and on the outer membrane protein profile was assessed in an in vivo growth chamber. The virulence plasmid did not influence either extracellular growth or the expression of major outer membrane proteins. These observations demonstrate that the virulence plasmid is not involved in either the enteric phase of infection or the systemic dissemination of S. dublin but probably mediates the persistence of S. dublin at systemic sites. PMID:7790094

Supporting Parental Involvement in Children's Early Learning: Lessons from Community Childcare Centres in Dublin's Docklands

ERIC Educational Resources Information Center

Share, Michelle; Kerrins, Liz

2013-01-01

Recently in Ireland attention has been placed on the importance of parental involvement in early childhood care and education settings as seen in the Síolta Quality Standards and Aistear Curriculum Framework. Yet there is little Irish empirical evidence on parental involvement in childcare settings; on the involvement models being used, or on the…

Language Learning in Virtual Worlds: Designing for Languaging, the Role of Affordances

ERIC Educational Resources Information Center

Nocchi, Susanna

2014-01-01

This article will utilise data collected during SLItaliano, an Italian language course run in the Virtual World (VW) of Second Life® (SL®) in 2012. The course was offered to third level students of Italian as a Foreign Language (FL) in an Irish college, the Dublin Institute of Technology (DIT). It was designed and coordinated by the researcher and…

Investigation of a cutaneous delayed hypersensitivity response as a means of detecting Salmonella dublin infection in cattle.

PubMed

Aitken, M M; Hall, G A; Jones, P W

1978-05-01

Delayed hypersensitivity reactions developed 48 to 96 h after intradermal injection of killed Salmonella dublin in 25 of 28 cattle which had been inoculated intravenously, and in five of 10 cattle which had been inoculated orally with S dublin 24 to 493 days previously. Control animals showed no delayed hypersensitivity reactions. Persistence of infection in five of the intravenously inoculated and in four of the orally inoculated animals was confirmed by isolation of S dublin from the carcases at necropsy one week after skin testing. Failure to isolate the organism from the carcases of 21 animals which had reacted positively to the intradermal test did not eliminate the possibility of their being carriers of S dublin. Skin testing was concluded to be a reliable means of identifying animals which had been, and possibly still were, infected systemically with S dublin. However recovered animals might be falsely identified as infected. Repeated testing gave misleading results.

Wintertime aerosol chemical composition and source apportionment of the organic fraction across Ireland

NASA Astrophysics Data System (ADS)

Ovadnevaite, J.; Lin, C.; Ceburnis, D.; Huang, R. J. J.; O'Dowd, C. D. D.

2017-12-01

A national wide characterization of PM1 was studied for the first time using a high-time resolution Aerosol Chemical Speciation Monitor (ACSM) and Aethalometer in Ireland during the heating season. Dublin, the capital of Ireland, is the most polluted area with an average PM1 of 7.6 μg/m3, with frequent occurrence of peak concentration over 200 μg/m3 primarily due to solid fuels burning, while Mace Head, in the west coast, is least polluted with an average PM1 of 0.8 μg/m3 due to the distance from the emission sources. The organic aerosol is the most dominant species across Ireland, contributing 65%, 58%, 32%, 33% to total PM1 mass in Dublin, Birr, Carnsore Point, and Mace Head, respectively. Birr, a small town in the midland of Ireland, has comparable PM1 levels (4.8 μg/m3) and similar chemical compositions with that in Dublin. Carnsore Point, on the southeast coast, has similar composition with that at Mace Head, but nearly 3 times the levels of PM1 mass due to its relative closeness to other European countries. Positive matrix factorization (PMF) with the multi-linear engine (ME-2) was performed on the organic matrix to quantify the contribution of factor candidates. Peat burning was found to be the dominant factor across Ireland, contributing more than 40% of the total organic mass in Dublin and Birr while OOA is dominant at rural Carnsore Point and Mace Head. Possible geographic origins of PM1 species and organic factors using polar plots were explored. The findings of solid fuels burning (primarily peat burning) driving the pollution episodes suggest an elimination or controlled emission of solid fuels burning would reduce PM1 by at least 50%.

Groundwater conditions and studies in the Augusta–Richmond County area, Georgia, 2008–2009

USGS Publications Warehouse

Gonthier, Gerard; Lawrence, Stephen J.; Peck, Michael F.; Holloway, O. Gary

2011-01-01

Groundwater studies and monitoring efforts conducted during 2008–2009, as part of the U.S. Geological Survey (USGS) Cooperative Water Program with the City of Augusta in Richmond County, Georgia, provided data for the effective management of local water resources. During 2008–2009 the USGS completed: (1) installation of three monitoring wells and the collection of lithologic and geophysical logging data to determine the extent of hydrogeologic units, (2) collection of continuous groundwater-level data from wells near Well Fields 2 and 3, (3) collection of synoptic groundwater-level measurements and construction of potentiometric-surface maps in Richmond County to establish flow gradients and groundwater-flow directions in the Dublin and Midville aquifer systems, (4) completion of a 24-hour aquifer test to determine hydraulic characteristics of the lower Dublin aquifer, and upper and lower Midville aquifers in Well Field 2, and (5) collection of groundwater samples from selected wells in Well Field 2 for laboratory analysis of volatile organic compounds and groundwater tracers to assess groundwater quality and estimate the time of groundwater recharge. Potentiometric-surface maps of the Dublin and Midville aquifer systems for 2008–2009 indicate that the general groundwater flow direction within Richmond County is eastward toward the Savannah River, with the exception of the area around Well Field 2, where pumping interrupts the eastward flow of water toward the Savannah River and causes flow lines to bend toward the center of pumping. Results from a 24-hour aquifer test conducted in 2009 within the upper and lower Midville aquifers at Well Field 2 indicated a transmissivity and storativity for the upper and lower Midville aquifers, combined, of 4,000 feet-squared per day and 2x10-4, respectively. The upper and lower Midville aquifers and the middle lower Midville confining unit, which is 85-feet thick in this area, yielded horizontal hydraulic conductivity and specific storage values of about 45 feet per day and 2x10-6 ft-1, respectively. Results from the 24-hour aquifer test also indicate a low horizontal hydraulic conductivity for the lower Dublin aquifer of less than 1 foot per day. Of the 35 volatile organic compounds (VOCs) analyzed in 23 groundwater samples during 2008–2009, only six were detected above laboratory reporting limits in samples from eight wells. No concentration in groundwater samples collected during 2008–2009 exceeded drinking water standards. Trichloroethene had the maximum VOC concentration (1.9 micrograms per liter) collected from a water sample during 2008–2009. Water-quality sampling of several wells near Well Field 2 indicate that, while in operation, the northernmost production well might have diverted groundwater, containing low levels of trichloroethene from at least two other production wells. Analysis of sulfur hexafluoride data indicate the average year of recharge ranges between 1981 and 1984 for water samples from five wells open to the upper and lower Midville aquifers, and 1991 for a water sample from one shallow well open to the lower Dublin aquifer. All of these ages suggest a short flow path and nearby source of contamination. The actual source of low levels of VOCs at Well Field 2 remains unknown. Three newly installed monitoring wells indicate that hydrogeologic units beneath Well Fields 2 and 3 are composed of sand and clay layers. Hydrogeologic units, encountered at Well Field 2, in order of increasing depth are the lower Dublin confining unit, lower Dublin aquifer, upper Midville confining unit, upper Midville aquifer, lower Midville confining unit, and lower Midville aquifer. West of Well Field 3, hydrogeologic units, in order of increasing depth are the Upper Three Runs aquifer, Gordon confining unit, Gordon aquifer, lower Dublin confining unit, lower Dublin aquifer, upper Midville confining unit, upper Midville aquifer, lower Midville confining unit, and lower Midville aquifer.

Participation of patients and family members in healthcare services at the service and national levels: A lesson learned in Dublin, Ireland.

PubMed

Whiston, Lucy; Barry, Joe M; Darker, Catherine D

2017-03-01

Identify the current amount and intensity of patient and family participation at the patient, service and national levels from a diabetes and a psychiatric service perspective. Establish the current level of support for greater participation and related characteristics. Researcher-administered questionnaires were conducted with 738 patients and family members in an outpatient type 2 diabetes service and an outpatient psychiatric service, both in Dublin, Ireland. Patient and family participation at the service and national levels are restricted to the provision of information. Typically no involvement in discussions or the decision -making process is reported. The majority of participants favour greater patient participation at the service level (537/669; 80.3%) and the national level (561/651; 86.2%). Greater support for patient and family member participation is significantly associated with participant's age, service satisfaction and level of education. Patient and family participation is greatest at the patient level. The majority of patients and family members support greater participation at the service and national levels. The best way to implement participation needs to be identified. There needs to be a greater focus on participation at the service level. The role of family members also needs to be investigated further. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

The Homolog of the Gene bstA of the BTP1 Phage from Salmonella enterica Serovar Typhimurium ST313 Is an Antivirulence Gene in Salmonella enterica Serovar Dublin.

PubMed

Herrero-Fresno, Ana; Espinel, Irene Cartas; Spiegelhauer, Malene Roed; Guerra, Priscila Regina; Andersen, Karsten Wiber; Olsen, John Elmerdahl

2018-01-01

In a previous study, a novel virulence gene, bstA , identified in a Salmonella enterica serovar Typhimurium sequence type 313 (ST313) strain was found to be conserved in all published Salmonella enterica serovar Dublin genomes. In order to analyze the role of this gene in the host-pathogen interaction in S Dublin, a mutant where this gene was deleted ( S Dublin Δ bstA ) and a mutant which was further genetically complemented with bstA ( S Dublin 3246-C) were constructed and tested in models of in vitro and in vivo infection as well as during growth competition assays in M9 medium, Luria-Bertani broth, and cattle blood. In contrast to the results obtained for a strain of S Typhimurium ST313, the lack of bstA was found to be associated with increased virulence in S Dublin. Thus, S Dublin Δ bstA showed higher levels of uptake than the wild-type strain during infection of mouse and cattle macrophages and higher net replication within human THP-1 cells. Furthermore, during mouse infections, S Dublin Δ bstA was more virulent than the wild type following a single intraperitoneal infection and showed an increased competitive index during competitive infection assays. Deletion of bstA did not affect either the amount of cytokines released by THP-1 macrophages or the cytotoxicity toward these cells. The histology of the livers and spleens of mice infected with the wild-type strain and the S Dublin Δ bstA mutant revealed similar levels of inflammation between the two groups. The gene was not important for adherence to or invasion of human epithelial cells and did not influence bacterial growth in rich medium, minimal medium, or cattle blood. In conclusion, a lack of bstA affects the pathogenicity of S Dublin by decreasing its virulence. Therefore, it might be regarded as an antivirulence gene in this serovar. Copyright © 2017 American Society for Microbiology.

75 FR 76953 - Foreign-Trade Zone 238-Dublin, VA Site Renumbering Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-10

... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Foreign-Trade Zone 238--Dublin, VA Site Renumbering Notice Foreign-Trade Zone 238 was approved by the Foreign-Trade Zones Board on August 5, 1999 (Board Order 1047). FTZ 238 currently consists of 1 ``site'' totaling 50 acres in the Dublin area. The...

The Dublin Declaration on Maternal Health Care and Anti-Abortion Activism

PubMed Central

2017-01-01

Abstract The Dublin Declaration on Maternal Healthcare—issued by self-declared pro-life activists in Ireland in 2012—states unequivocally that abortion is never medically necessary, even to save the life of a pregnant woman. This article examines the influence of the Dublin Declaration on abortion politics in Latin America, especially El Salvador and Chile, where it has recently been used in pro-life organizing to cast doubt on the notion that legalizing abortion will reduce maternal mortality. Its framers argue that legalizing abortion will not improve maternal mortality rates, but reproductive rights advocates respond that the Dublin Declaration is junk science designed to preserve the world’s most restrictive abortion laws. Analyzing the strategy and impact of the Dublin Declaration brings to light one of the tactics used in anti-abortion organizing. PMID:28630540

The Dublin Declaration on Maternal Health Care and Anti-Abortion Activism: Examples from Latin America.

PubMed

Morgan, Lynn M

2017-06-01

The Dublin Declaration on Maternal Healthcare-issued by self-declared pro-life activists in Ireland in 2012-states unequivocally that abortion is never medically necessary, even to save the life of a pregnant woman. This article examines the influence of the Dublin Declaration on abortion politics in Latin America, especially El Salvador and Chile, where it has recently been used in pro-life organizing to cast doubt on the notion that legalizing abortion will reduce maternal mortality. Its framers argue that legalizing abortion will not improve maternal mortality rates, but reproductive rights advocates respond that the Dublin Declaration is junk science designed to preserve the world's most restrictive abortion laws. Analyzing the strategy and impact of the Dublin Declaration brings to light one of the tactics used in anti-abortion organizing.

What is FirstSchool? Issues in PreK-3rd Education. Number One

ERIC Educational Resources Information Center

Ritchie, Sharon; Maxwell, Kelly; Clifford, Richard

2009-01-01

FirstSchool is part of a national PreK-3rd movement of schools, districts, educators and universities seeking to improve how children from ages 3 to 8 learn and develop in schools. While these different projects use a variety of names, all are working to connect high-quality PreK programs with high-quality elementary schools. FirstSchool is…

Web-Based Learning in a Geometry Course

ERIC Educational Resources Information Center

Chan, Hsungrow; Tsai, Pengheng; Huang, Tien-Yu

2006-01-01

This study concerns applying Web-based learning with learner controlled instructional materials in a geometry course. The experimental group learned in a Web-based learning environment, and the control group learned in a classroom. We observed that the learning method accounted for a total variation in learning effect of 19.1% in the 3rd grade and…

Genetic diversity, anti-microbial resistance, plasmid profile and frequency of the Vi antigen in Salmonella Dublin strains isolated in Brazil.

PubMed

Vilela, F P; Frazão, M R; Rodrigues, D P; Costa, R G; Casas, M R T; Fernandes, S A; Falcão, J P; Campioni, F

2018-02-01

Salmonella Dublin is strongly adapted to cattle causing enteritis and/or systemic disease with high rates of mortality. However, it can be sporadically isolated from humans, usually causing serious disease, especially in patients with underlying chronic diseases. The aim of this study was to molecularly type S. Dublin strains isolated from humans and animals in Brazil to verify the diversity of these strains as well as to ascertain possible differences between strains isolated from humans and animals. Moreover, the presence of the capsular antigen Vi and the plasmid profile was characterized in addition to the anti-microbial resistance against 15 drugs. For this reason, 113 S. Dublin strains isolated between 1983 and 2016 from humans (83) and animals (30) in Brazil were typed by PFGE and MLVA. The presence of the capsular antigen Vi was verified by PCR, and the phenotypic expression of the capsular antigen was determined serologically. Also, a plasmid analysis for each strain was carried out. The strains studied were divided into 35 different PFGE types and 89 MLVA-types with a similarity of ≥80% and ≥17.5%, respectively. The plasmid sizes found ranged from 2 to >150 kb and none of the strains studied presented the capsular antigen Vi. Resistance or intermediate resistance was found in 23 strains (20.3%) that were resistant to ampicillin, ciprofloxacin, chloramphenicol, imipenem, nalidixic acid, piperacillin, streptomycin and/or tetracycline. The majority of the S. Dublin strains studied and isolated over a 33-year period may descend from a common subtype that has been contaminating humans and animals in Brazil and able to cause invasive disease even in the absence of the capsular antigen. The higher diversity of resistance phenotypes in human isolates, as compared with animal strains, may be a reflection of the different anti-microbial treatments used to control S. Dublin infections in humans in Brazil. © 2017 Blackwell Verlag GmbH.

Coming to Journalism: A Comparative Case Study of Postgraduate Students in Dublin and Amman

ERIC Educational Resources Information Center

O'Boyle, Neil; Knowlton, Steven

2015-01-01

This article presents findings from a pilot study of postgraduate journalism students in Dublin and Amman. The study compared professional outlooks and social characteristics of students in both contexts and examined institutional settings. The study finds that journalism students in Dublin and Amman have very similar views on the profession,…

Physical stratigraphy and hydrostratigraphy of Upper Cretaceous and Paleocene sediments, Burke and Screven Counties, Georgia

USGS Publications Warehouse

Falls, W.F.; Baum, J.S.; Prowell, D.C.

1997-01-01

Six geologic units are recognized in the Cretaceous and the Paleocene sediments of eastern Burke and Screven Counties in Georgia on the basis of lithologic, geophysical, and paleontologic data collected from three continuously cored testholes in Georgia and one testhole in South Carolina. The six geologic units are separated by regional unconformities and are designated from oldest to youngest as the Cape Fear Formation, the Middendorf Formation, the Black Creek Group (undivided), and the Steel Creek Formation in the Upper Cretaceous section, and the Ellenton and the Snapp Formations in the Paleocene section. The geologic units provide a spatial and temporal framework for the identification and correlation of a basal confining unit beneath the Midville aquifer system and five aquifers and five confining units in the Dublin and the Midville aquifer systems. The Dublin aquifer system is divided hydrostratigraphically into the Millers Pond, the upper Dublin, and the lower Dublin aquifers. The Midville aquifer system is divided hydrostratigraphically into the upper and the lower Midville aquifers. The fine-grained sediments of the Millers Pond, the lower Dublin, and the lower Midville confining units are nonmarine deposits and are present in the upper part of the Snapp Formation, the Black Creek Group (undivided), and the Middendorf Formation, respectively. Hydrologic data for specific sets of monitoring wells at the Savannah River Site in South Carolina and the Millers Pond site in Georgia confirm that these three units are leaky confining units and locally impede vertical ground-water flow between adjacent aquifers. The fine-grained sediments of the upper Dublin and the upper Midville confining units are marine-deltaic deposits of the Ellenton Formation and the Black Creek Group (undivided), respectively. Hydrologic data confirm that the upper Dublin confining unit regionally impedes vertical ground-water flow on both sides of the Savannah River. The upper Midville confining unit impedes vertical ground-water flow in the middle and downdip parts of the study area and is a leaky confining unit in the updip part of the study area. Recognition of the upper Dublin confining unit as a regional confining unit between the Millers Pond and the upper Dublin aquifers also confirms that the Millers Pond aquifer is a separate hydrologic unit from the rest of the Dublin aquifer system. This multi-aquifer framework increases the vertical hydrostratigraphic resolution of hydraulic properties and gradients in the Dublin and Midville aquifer systems for the investigation of ground-water flow beneath the Savannah River in the vicinity of the U.S. Department of Energy Savannah River Site.

Intestinal Epithelial Cells Modulate Antigen-Presenting Cell Responses to Bacterial DNA

PubMed Central

Campeau, J. L.; Salim, S. Y.; Albert, E. J.; Hotte, N.

2012-01-01

Intestinal epithelial cells and antigen-presenting cells orchestrate mucosal innate immunity. This study investigated the role of bacterial DNA in modulating epithelial and bone marrow-derived antigen-presenting cells (BM-APCs) and subsequent T-lymphocyte responses. Murine MODE-K epithelial cells and BM-APCs were treated with DNA from either Bifidobacterium breve or Salmonella enterica serovar Dublin directly and under coculture conditions with CD4+ T cells. Apical stimulation of MODE-K cells with S. Dublin DNA enhanced secretion of cytokines from underlying BM-APCs and induced interleukin-17 (IL-17) and gamma interferon (IFN-γ) secretion from CD4+ T cells. Bacterial DNA isolated from either strain induced maturation and increased cytokine secretion from BM-APCs. Conditioned medium from S. Dublin-treated MODE-K cells elicited an increase in cytokine secretion similar to that seen for S. Dublin DNA. Treatment of conditioned medium from MODE-K cells with RNase and protease prevented the S. Dublin-induced increased cytokine secretion. Oral feeding of mice with B. breve DNA resulted in enhanced levels of colonic IL-10 and transforming growth factor β (TGFβ) compared with what was seen for mice treated with S. Dublin DNA. In contrast, feeding mice with S. Dublin DNA increased levels of colonic IL-17 and IL-12p70. T cells from S. Dublin DNA-treated mice secreted high levels of IL-12 and IFN-γ compared to controls and B. breve DNA-treated mice. These results demonstrate that intestinal epithelial cells are able to modulate subsequent antigen-presenting and T-cell responses to bacterial DNA with pathogenic but not commensal bacterial DNA inducing effector CD4+ T lymphocytes. PMID:22615241

Self-Grading and Peer-Grading for Formative and Summative Assessments in 3rd through 12th Grade Classrooms: A Meta-Analysis

ERIC Educational Resources Information Center

Sanchez, Carmen E.; Atkinson, Kayla M.; Koenka, Alison C.; Moshontz, Hannah; Cooper, Harris

2017-01-01

The "assessment 'for' learning" movement in education has increased attention to self-grading and peer-grading practices in primary and secondary schools. This research synthesis examined several questions pertaining to the use of self-grading and peer-grading in conjunction with criterion-referenced testing in 3rd- through…

American Society for Parenteral & Enteral Nutrition

MedlinePlus

... Center Advertising and Sponsorship Learn More ASPEN Enteral Nutrition by the Numbers: EN Data Across the Healthcare Continuum Learn More The ASPEN Adult Nutrition Support Core Curriculum, 3rd Edition Has Arrived! The ...

Report from the International Conference on Dublin Core and Metadata Applications, 2001.

ERIC Educational Resources Information Center

Sugimoto, Shigeo; Adachi, Jun; Baker, Thomas; Weibel, Stuart

This paper describes the International Conference on Dublin Core and Metadata Applications 2001 (DC-2001), the ninth major workshop of the Dublin Core Metadata Initiative (DCMI), which was held in Tokyo in October 2001. DC-2001 was a week-long event that included both a workshop and a conference. In the tradition of previous events, the workshop…

The Stage and the City: Narrative, Identity and Place in Dermot Bolger's "The Ballymun Trilogy" (2004-2008)

ERIC Educational Resources Information Center

Malone, Niamh; O'Sullivan, Carmel

2011-01-01

Located two miles from Dublin Airport, Ballymun was built (1966-9) to accommodate people displaced from the inner-city slums dramatised in Sean O'Casey's Dublin Trilogy. "The Stage and the City" draws on the author's research project at Trinity College Dublin, on Theatre and Urban Regeneration. Specifically, it situates Dermot Bolger's…

The diagnosis of salmonella abortion in cattle with particular reference to Salmonella dublin. A review.

PubMed Central

Hinton, M.

1977-01-01

The diagnosis of abortion in cattle caused by Salmonella dublin depends upon the isolation of the organism from either the products of conception, uterine discharges, vaginal mucus or milk together with serological evidence of active infection. S. dublin may be isolated when an active or a latent carrier cow abourts but in these cases an active infection will not be demonstrable. The retrospective identification of a case of S. dublin abortion may prove difficult as excretion of the organism is usually transient and the serum agglutinating antibodies frequently fall to low titres soon after the abortion. PMID:328768

Dublin and Irish politics in the age of Charles Lucas.

PubMed

Hill, J

2015-09-01

In addition to his contributions to medicine, Charles Lucas had a long career in politics, starting in the 1740s as a guild representative on the lower house of Dublin corporation, and culminating in his election to the Irish House of Commons in 1761. By examining the background in Dublin and Irish politics, this paper explores Lucas' impact on the electorate, and how it was that he was able to win a parliamentary seat in Dublin and retain it for a decade while he campaigned in support of a range of important Patriot issues. Lucas had none of the qualifications that would normally be required for a successful politician. His father held some land, but as a younger son who had to make a living, Charles was apprenticed to a Dublin apothecary. Nor did he have the political connections that might have compensated for a lack of land, wealth, or status. But Lucas possessed other advantages, notably an education that enabled him to read the city's medieval charters, identifying areas where the Dublin freemen had lost 'ancient rights', and some experience of publishing, so that he could appeal to the electorate. Lucas' remarkable political success stemmed from both local circumstances and his own personal qualities.

Genomic comparison of the closely-related Salmonella enterica serovars enteritidis, dublin and gallinarum

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matthews, T. David; Schmieder, Robert; Silva, Genivaldo G. Z.

The Salmonella enterica serovars Enteritidis, Dublin, and Gallinarum are closely related but differ in virulence and host range. To identify the genetic elements responsible for these differences and to better understand how these serovars are evolving, we sequenced the genomes of Enteritidis strain LK5 and Dublin strain SARB12 and compared these genomes to the publicly available Enteritidis P125109, Dublin CT 02021853 and Dublin SD3246 genome sequences. We also compared the publicly available Gallinarum genome sequences from biotype Gallinarum 287/91 and Pullorum RKS5078. Using bioinformatic approaches, we identified single nucleotide polymorphisms, insertions, deletions, and differences in prophage and pseudogene content betweenmore » strains belonging to the same serovar. Through our analysis we also identified several prophage cargo genes and pseudogenes that affect virulence and may contribute to a host-specific, systemic lifestyle. These results strongly argue that the Enteritidis, Dublin and Gallinarum serovars of Salmonella enterica evolve by acquiring new genes through horizontal gene transfer, followed by the formation of pseudogenes. As a result, the loss of genes necessary for a gastrointestinal lifestyle ultimately leads to a systemic lifestyle and niche exclusion in the host-specific serovars.« less

Genomic comparison of the closely-related Salmonella enterica serovars enteritidis, dublin and gallinarum

DOE PAGES

Matthews, T. David; Schmieder, Robert; Silva, Genivaldo G. Z.; ...

2015-06-03

The Salmonella enterica serovars Enteritidis, Dublin, and Gallinarum are closely related but differ in virulence and host range. To identify the genetic elements responsible for these differences and to better understand how these serovars are evolving, we sequenced the genomes of Enteritidis strain LK5 and Dublin strain SARB12 and compared these genomes to the publicly available Enteritidis P125109, Dublin CT 02021853 and Dublin SD3246 genome sequences. We also compared the publicly available Gallinarum genome sequences from biotype Gallinarum 287/91 and Pullorum RKS5078. Using bioinformatic approaches, we identified single nucleotide polymorphisms, insertions, deletions, and differences in prophage and pseudogene content betweenmore » strains belonging to the same serovar. Through our analysis we also identified several prophage cargo genes and pseudogenes that affect virulence and may contribute to a host-specific, systemic lifestyle. These results strongly argue that the Enteritidis, Dublin and Gallinarum serovars of Salmonella enterica evolve by acquiring new genes through horizontal gene transfer, followed by the formation of pseudogenes. As a result, the loss of genes necessary for a gastrointestinal lifestyle ultimately leads to a systemic lifestyle and niche exclusion in the host-specific serovars.« less

Genomic Comparison of the Closely-Related Salmonella enterica Serovars Enteritidis, Dublin and Gallinarum

PubMed Central

Matthews, T. David; Schmieder, Robert; Silva, Genivaldo G. Z.; Busch, Julia; Cassman, Noriko; Dutilh, Bas E.; Green, Dawn; Matlock, Brian; Heffernan, Brian; Olsen, Gary J.; Farris Hanna, Leigh; Schifferli, Dieter M.; Maloy, Stanley; Dinsdale, Elizabeth A.; Edwards, Robert A.

2015-01-01

The Salmonella enterica serovars Enteritidis, Dublin, and Gallinarum are closely related but differ in virulence and host range. To identify the genetic elements responsible for these differences and to better understand how these serovars are evolving, we sequenced the genomes of Enteritidis strain LK5 and Dublin strain SARB12 and compared these genomes to the publicly available Enteritidis P125109, Dublin CT 02021853 and Dublin SD3246 genome sequences. We also compared the publicly available Gallinarum genome sequences from biotype Gallinarum 287/91 and Pullorum RKS5078. Using bioinformatic approaches, we identified single nucleotide polymorphisms, insertions, deletions, and differences in prophage and pseudogene content between strains belonging to the same serovar. Through our analysis we also identified several prophage cargo genes and pseudogenes that affect virulence and may contribute to a host-specific, systemic lifestyle. These results strongly argue that the Enteritidis, Dublin and Gallinarum serovars of Salmonella enterica evolve by acquiring new genes through horizontal gene transfer, followed by the formation of pseudogenes. The loss of genes necessary for a gastrointestinal lifestyle ultimately leads to a systemic lifestyle and niche exclusion in the host-specific serovars. PMID:26039056

INTERNATIONAL APPROACH TO LEARNING DISABILITIES OF CHILDREN AND YOUTH, ANNUAL INTERNATIONAL CONFERENCE OF THE ASSOCIATION FOR CHILDREN WITH LEARNING DISABILITIES, INC. (3RD, TULSA, OKLAHOMA, MARCH 3-5, 1966).

ERIC Educational Resources Information Center

MESIROW, LOUISE

SELECTED PRESENTATIONS (27) OF PARTICIPANTS IN THE THIRD INTERNATIONAL CONFERENCE OF THE ASSOCIATION FOR CHILDREN WITH LEARNING DISABILITIES ARE PRESENTED. PAPERS FROM GENERAL SESSIONS DISCUSS THE FOLLOWING TOPICS--LEARNING DISABILITIES, A SCREENING SCALE, DIAGNOSIS AND REMEDIATION, ETIOLOGY, AND READING. OTHER TOPIC AREAS INCLUDE MEDICATION, THE…

LC21-Hopes and Cautions for the Library of Congress; The NSF National Science, Mathematics, Engineering, and Technology Education Digital Library (NSDL) Program: A Progress Report; A Grammar of Dublin Core; Measuring the Impact of an Electronic Journal Collection on Library Costs: A Framework and Preliminary Observations; Emulation As a Digital Preservation Strategy.

ERIC Educational Resources Information Center

O'Donnell, James J.; Zia, Lee L.; Baker, Thomas; Montgomery, Carol Hansen; Granger, Stewart

2000-01-01

Includes five articles: (1) discusses Library of Congress efforts to include digital materials; (2) describes the National Science Foundation (NSF) digital library program to improve science, math, engineering, and technology education; (3) explains Dublin Core grammar; (4) measures the impact of electronic journals on library costs; and (5)…

Learning in Adulthood: A Comprehensive Guide, 3rd Edition

ERIC Educational Resources Information Center

Merriam, Sharan B.; Caffarella, Rosemary S.; Baumgartner, Lisa M.

2006-01-01

In this updated landmark book, the authors have gathered the seminal work and most current thinking on adult learning into one volume. This book addresses a wide range of topics including: Who are adult learners? How do adults learn? Why are adults involved in learning activities? How does the social context shape the learning that adults are…

Production of Optical Quality Free Standing Diamond Wafer

DTIC Science & Technology

2008-05-19

Title : Production of Optical Quality Free Standing Diamond Wafer Prime Contractor : Onyx Optics, Inc. 6551 Sierra Lane Dublin, Ca 94568...www.onyxoptics.com Program Manager : Helmuth Meissner Onyx Optics, Inc. 6551 Sierra Lane Dublin, CA 94568 Email: hmeissner@onyxoptics.com Ph: 925...PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Onyx Optics, Inc. 6551 Sierra Lane Dublin, Ca 94568 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING

Ego depletion interferes with rule-defined category learning but not non-rule-defined category learning.

PubMed

Minda, John P; Rabi, Rahel

2015-01-01

Considerable research on category learning has suggested that many cognitive and environmental factors can have a differential effect on the learning of rule-defined (RD) categories as opposed to the learning of non-rule-defined (NRD) categories. Prior research has also suggested that ego depletion can temporarily reduce the capacity for executive functioning and cognitive flexibility. The present study examined whether temporarily reducing participants' executive functioning via a resource depletion manipulation would differentially impact RD and NRD category learning. Participants were either asked to write a story with no restrictions (the control condition), or without using two common letters (the ego depletion condition). Participants were then asked to learn either a set of RD categories or a set of NRD categories. Resource depleted participants performed more poorly than controls on the RD task, but did not differ from controls on the NRD task, suggesting that self regulatory resources are required for successful RD category learning. These results lend support to multiple systems theories and clarify the role of self-regulatory resources within this theory.

Ego depletion interferes with rule-defined category learning but not non-rule-defined category learning

PubMed Central

Minda, John P.; Rabi, Rahel

2015-01-01

Considerable research on category learning has suggested that many cognitive and environmental factors can have a differential effect on the learning of rule-defined (RD) categories as opposed to the learning of non-rule-defined (NRD) categories. Prior research has also suggested that ego depletion can temporarily reduce the capacity for executive functioning and cognitive flexibility. The present study examined whether temporarily reducing participants’ executive functioning via a resource depletion manipulation would differentially impact RD and NRD category learning. Participants were either asked to write a story with no restrictions (the control condition), or without using two common letters (the ego depletion condition). Participants were then asked to learn either a set of RD categories or a set of NRD categories. Resource depleted participants performed more poorly than controls on the RD task, but did not differ from controls on the NRD task, suggesting that self regulatory resources are required for successful RD category learning. These results lend support to multiple systems theories and clarify the role of self-regulatory resources within this theory. PMID:25688220

Cooperative Learning as a Democratic Learning Method

ERIC Educational Resources Information Center

Erbil, Deniz Gökçe; Kocabas, Ayfer

2018-01-01

In this study, the effects of applying the cooperative learning method on the students' attitude toward democracy in an elementary 3rd-grade life studies course was examined. Over the course of 8 weeks, the cooperative learning method was applied with an experimental group, and traditional methods of teaching life studies in 2009, which was still…

Proflavine-mediated inactivation of Salmonella dublin exposed to visible sunlight in natural fresh water.

PubMed

Kussovski, V K; Hristov, A E; Radoucheva, T S

2001-01-01

The survival of Salmonella dublin exposed to visible sunlight, and heterotrophic bacteria in freshwater microcosms in the presence and absence of the photosensitizer proflavine, was studied. Enumeration of S. dublin and the heterotrophic bacteria showed that in both illuminated and nonilluminated systems (without proflavine) the bacteria remained viable and culturable for at least 6 days. The optimal proflavine concentration (no effect in the dark and a maximal photoinactivation of salmonellae after irradiation) was 2 mg l(-1). In contrast to S. dublin, the heterotrophic bacteria overcame the initial inhibitory effect of proflavine. The possible use of photosterilization against contamination with pathogenic bacteria in water model ecosystems, is discussed.

The Less Widely Taught Languages of Europe. Proceedings of the Joint United Nations Educational, Scientific, and Cultural Organization, International Association of Applied Linguistics, and Irish Association of Applied Linguistics Symposium (St. Patrick's College, Dublin, Ireland, April 23-25, 1987).

ERIC Educational Resources Information Center

Mathuna, Liam Mac, Ed.; And Others

Papers presented at a symposium on Europe's less commonly taught languages include the following: "The Necessity of Dialogue" (Marcel de Greve); "Socio- and Psycholinguistic Interference in Teaching Foreign Languages" (Penka Ilieva-Baltova); "Satellite Television, National Television, and Video in Teaching/Learning Less…

Design Fixation and Cooperative Learning in Elementary Engineering Design Project: A Case Study

ERIC Educational Resources Information Center

Luo, Yi

2015-01-01

This paper presents a case study examining 3rd, 4th and 5th graders' design fixation and cooperative learning in an engineering design project. A mixed methods instrument, the Cooperative Learning Observation Protocol (CLOP), was adapted to record frequency and class observation on cooperative learning engagement through detailed field notes.…

Should Any Workplace Be Exempt from Smoke-Free Law: The Irish Experience

PubMed Central

McCaffrey, M.; Goodman, P.; Gavigan, A.; Kenny, C.; Hogg, C.; Byrne, L.; McLaughlin, J.; Young, K.; Clancy, L.

2012-01-01

Background. In 2004, the Irish Government introduced national legislation banning smoking in workplaces; with exemptions for “a place of residence”. This paper summarises three Irish studies of exempted premises; prisons, psychiatric hospitals and nursing homes. Methods. PM2.5 and nicotine were measured in nursing homes and psychiatric hospitals, in addition to ultrafine particles in the hospitals. In the prisons, officers (n = 30) completed exhaled breath Carbon Monoxide (CO) measurements. Questionnaires determined officers' opinion on introducing smoking prohibitions in prisons. Nursing home smoking policies were examined and questionnaires completed by staff regarding workplace secondhand smoke (SHS) exposure. Findings. Ultrafine particle concentrations in psychiatric hospitals averaged 130,000  cm3, approximately 45% higher than Dublin pub (35.5 μg/m3) pre ban. PM2.5 levels in psychiatric hospitals (39.5 μg/m3) were similar to Dublin pubs (35.5 μg/m3) pre ban. In nursing homes permitting smoking, similar PM2.5 levels (33 μg/m3) were measured, with nicotine levels (0.57 μg/m3) four times higher than “non-smoking” nursing homes (0.13 μg/m3). In prisons, 44% of non-smoking officers exhibited exhaled breath CO criteria for light to heavy smokers. Conclusions. With SHS exposure levels in some exempted workplaces similar to Dublin pubs levels pre ban, policies ensuring full protection must be developed and implemented as a right for workers, inmates and patients. PMID:22693522

Should any workplace be exempt from smoke-free law: the Irish experience.

PubMed

McCaffrey, M; Goodman, P; Gavigan, A; Kenny, C; Hogg, C; Byrne, L; McLaughlin, J; Young, K; Clancy, L

2012-01-01

In 2004, the Irish Government introduced national legislation banning smoking in workplaces; with exemptions for "a place of residence". This paper summarises three Irish studies of exempted premises; prisons, psychiatric hospitals and nursing homes. PM(2.5) and nicotine were measured in nursing homes and psychiatric hospitals, in addition to ultrafine particles in the hospitals. In the prisons, officers (n = 30) completed exhaled breath Carbon Monoxide (CO) measurements. Questionnaires determined officers' opinion on introducing smoking prohibitions in prisons. Nursing home smoking policies were examined and questionnaires completed by staff regarding workplace secondhand smoke (SHS) exposure. Ultrafine particle concentrations in psychiatric hospitals averaged 130,000  cm(3), approximately 45% higher than Dublin pub (35.5 μg/m(3)) pre ban. PM(2.5) levels in psychiatric hospitals (39.5 μg/m(3)) were similar to Dublin pubs (35.5 μg/m(3)) pre ban. In nursing homes permitting smoking, similar PM(2.5) levels (33 μg/m(3)) were measured, with nicotine levels (0.57 μg/m(3)) four times higher than "non-smoking" nursing homes (0.13 μg/m(3)). In prisons, 44% of non-smoking officers exhibited exhaled breath CO criteria for light to heavy smokers. With SHS exposure levels in some exempted workplaces similar to Dublin pubs levels pre ban, policies ensuring full protection must be developed and implemented as a right for workers, inmates and patients.

Measles outbreak in Dublin, 2000.

PubMed

McBrien, Jacqueline; Murphy, John; Gill, Denis; Cronin, Mary; O'Donovan, Catherine; Cafferkey, Mary T

2003-07-01

An outbreak of measles occurred in Ireland between December 1999 and July 2000. The majority of cases were in north Dublin, the catchment area of The Children's University Hospital (TCUH). Details of all of the 111 children attending the hospital with a diagnosis of measles between December 1999 and July 2000 were prospectively entered into a database. Charts were subsequently reviewed to extract epidemiologic and clinical details. National figures were obtained from the National Disease Surveillance Centre. In the study period 355 attended TCUH with a serologic or clinical diagnosis of measles, and 111 were admitted (47% female, 53% male). The main indications for admission were dehydration in 79%, pneumonia or pneumonitis in 47% and tracheitis in 32%. Thirteen children (11.7% of those admitted) required treatment in the intensive care unit, and in 7 of these mechanical ventilation was necessary. There were 3 deaths as a result of measles. Public health measures to curb spread of the disease included promotion of immunization for susceptible children nationally and recommending administration of measles-mumps-rubella vaccine (MMR) from the age of 6 months, in North Dublin. This outbreak of measles posed a major challenge to the hospital and the community for the first half of 2000. The national MMR immunization rate before the outbreak was gravely suboptimal at 79%, whereas the rate in North Dublin, the catchment area of TCUH, was <70%. Three children died as a result of a vaccine-preventable illness.

Neurobiological Underpinnings of Math and Reading Learning Disabilities

PubMed Central

Ashkenazi, Sarit; Black, Jessica M.; Abrams, Daniel A.; Hoeft, Fumiko; Menon, Vinod

2013-01-01

The primary goal of this review is to highlight current research and theories describing the neurobiological basis of math (MD), reading (RD), and comorbid math and reading disability (MD+RD). We first describe the unique brain and cognitive processes involved in acquisition of math and reading skills, emphasizing similarities and differences in each domain. Next we review functional imaging studies of MD and RD in children, integrating relevant theories from experimental psychology and cognitive neuroscience to characterize the functional neuroanatomy of cognitive dysfunction in MD and RD. We then review recent research on the anatomical correlates of MD and RD. Converging evidence from morphometry and tractography studies are presented to highlight distinct patterns of white matter pathways which are disrupted in MD and RD. Finally, we examine how the intersection of MD and RD provides a unique opportunity to clarify the unique and shared brain systems which adversely impact learning and skill acquisition in MD and RD, and point out important areas for future work on comorbid learning disabilities. PMID:23572008

Histopathology case definition of naturally acquired Salmonella enterica serovar Dublin infection in young Holstein cattle in the northeastern United States.

PubMed

Pecoraro, Heidi L; Thompson, Belinda; Duhamel, Gerald E

2017-11-01

Salmonella enterica subsp. enterica serovar Dublin ( Salmonella Dublin) is a host-adapted bacterium that causes high morbidity and mortality in dairy cattle worldwide. A retrospective search of archives at the New York Animal Health Diagnostic Center revealed 57 culture-confirmed Salmonella Dublin cases from New York and Pennsylvania in which detailed histology of multiple tissues was available. Tissues routinely submitted by referring veterinarians for histologic evaluation included sections of heart, lungs, liver, spleen, and lymph nodes. Of the 57 S almonella Dublin-positive cases, all were Holstein breed, 53 were female (93%), and 49 (86%) were <6 mo of age. Specifically, in calves <6 mo of age, >90% (45 of 49) of lungs, 90% (28 of 31) of livers, 50% (11 of 22) of spleens, and 62% (18 of 29) of lymph nodes examined had moderate-to-severe inflammation with or without necrosis. Inconstant lesions were seen in 48% (10 of 21) of hearts examined, and consisted of variable inflammatory infiltrates and rare areas of necrosis. We propose a histopathology case definition of Salmonella Dublin in <6-mo-old Holstein cattle that includes a combination of pulmonary alveolar capillary neutrophilia with or without hepatocellular necrosis and paratyphoid granulomas, splenitis, and lymphadenitis. These findings will assist in the development of improved protocols for the diagnosis of infectious diseases of dairy cattle.

Investigating traffic light violations by cyclists in Dublin City Centre.

PubMed

Richardson, Matthew; Caulfield, Brian

2015-11-01

This research examines the behaviour of cyclists in Dublin City with specific regard to red light running. A number of specific research questions are raised by this study. These questions address the impact of different infrastructure types on red light running, as well as the behavioural patterns and demographics of offending cyclists. Two data collection methods were used to gather information on cyclists in Dublin City - an observational survey and an online questionnaire. The observational surveys examined cyclist compliance with different traffic signal systems and the impact of on-road and off-road cycle infrastructure. An online questionnaire was used to get direct feedback from cyclists in Dublin City on the reasons (if any) they decide to commit infringement at traffic lights. With the recent growth of cycling in Dublin City (as well as many other international cities) it is vital to accommodate and manage this growing demand by ensuring the safety and road discipline of cyclists. The next few years will be crucial for the continued development of cycling in Dublin, particularly due to the increasing investment by transport planners in cycle infrastructure. It is therefore important to identify now the main factors which influence cyclist's decisions to break red lights in order to guide local traffic authorities in their efforts to reduce such transgressions. Copyright © 2015 Elsevier Ltd. All rights reserved.

The study of selective property of college student’s learning space

NASA Astrophysics Data System (ADS)

Nagai, Mizuki; Matsumoto, Yuji; Naka, Ryusuke

2018-05-01

These days, college students study not only at places designed for learning such as libraries in colleges, but also cafes in downtown while the number of facilities for learning run by colleges is increasing. Then I have researched facilities in college and those in downtown to find selective properties of college students’ learning space. First, I found by questionnaire survey that students chose “3rd place” such as cafes and fast food shops, second to their houses and libraries in college. Next, I found “psychological factor” were also affected their choice. Furthermore, they studied different subjects at different places. In experiments, I researched how effectively they studied each subject at every place. The results show that I find that places you like and places where learning efficiency is good are different. They learned the least effective at “3d place” regardless of what they learned. The result of how long they kept high-level intellectual activity at each place shows that they could work on the study with more motivation at their favorite place and 3rd place. On the other hand, at the 2nd place, they could study rather effectively, but could not keep concentration and motivation for a long time. In this way, college students have 2 patterns of choosing learning space.

Actes/Proceedings, Canadian Association of Applied Linguistics, 3rd Annual Meeting.

ERIC Educational Resources Information Center

Laval Univ., Quebec (Quebec). International Center for Research on Bilingualism.

These proceedings on applied linguistics and language learning contain the following papers: (1) "Audio-visual and Applied Linguistics; The State of the Question," by V. Ferenczi (in French); (2) "Research in Fundamental Language: The State of the Question," by B. Pottier (in French); (3) "Psycholinguistic Insights into Language Learning," by F.…

Fostering Engagement with the "Common European Framework of Reference for Languages" and the European Language Portfolio: Learning from Good Practice in University Language Centres

ERIC Educational Resources Information Center

Carson, Lorna

2016-01-01

This article begins with a brief overview of the aims and activities of the CercleS CEFR/ELP Focus Group. It goes on to report on some of the outcomes of the 2015 CercleS CEFR/ELP seminar hosted by the Centre for Language and Communication Studies at Trinity College Dublin. The five examples presented during the seminar's plenary sessions are…

Early Fractions Learning of 3rd Grade Students in SD Laboratorium Unesa

ERIC Educational Resources Information Center

Sari, Elisabet Ayunika Permata; Juniati, Dwi; Patahudin, Sitti Maesuri

2012-01-01

Fractions varied meanings is one of the causes of difficulties in learning fractions. These students should be given greater opportunities to explore the meaning of fractions before they learn the relationship between fractions and operations on fractions. Although students shading an area represents a fraction, it does not mean they really…

Best Practice in Motivation and Management in the Classroom. 3rd Edition

ERIC Educational Resources Information Center

Wiseman, Denise G.; Hunt, Gilbert H.

2013-01-01

Having the ability to manage the learning environment, motivate students in the environment, and offer instruction that itself is motivating and which contributes to students learning what they need to learn and acquiring skills they need to acquire characterizes effective teachers. To meet these expectations, teachers need highly developed skills…

There Are No New Lessons Learned, Just Old Lessons Relearned: A Case Study of Operation Iraqi Freedom Through the Eyes of Maslow

DTIC Science & Technology

2010-04-05

Abraham Maslow , a renowned American psychologist, prioritized human needs into four categories and his theory suggests that humans are motivated by...addressed through examination of other COIN and reconstruction operations. Endnotes 1 Abraham H. Maslow , Motivation and Personality, 3rd ed. (New...a basic understanding of Islam and provided a great contextual background for research. Maslow , Abraham H. Motivation and Personality, 3rd ed. New

Physiological and molecular responses of Lactuca sativa to colonization by Salmonella enterica serovar Dublin.

PubMed

Klerks, M M; van Gent-Pelzer, M; Franz, E; Zijlstra, C; van Bruggen, A H C

2007-08-01

This paper describes the physiological and molecular interactions between the human-pathogenic organism Salmonella enterica serovar Dublin and the commercially available mini Roman lettuce cv. Tamburo. The association of S. enterica serovar Dublin with lettuce plants was first determined, which indicated the presence of significant populations outside and inside the plants. The latter was evidenced from significant residual concentrations after highly efficient surface disinfection (99.81%) and fluorescence microscopy of S. enterica serovar Dublin in cross sections of lettuce at the root-shoot transition region. The plant biomass was reduced significantly compared to that of noncolonized plants upon colonization with S. enterica serovar Dublin. In addition to the physiological response, transcriptome analysis by cDNA amplified fragment length polymorphism analysis also provided clear differential gene expression profiles between noncolonized and colonized lettuce plants. From these, generally and differentially expressed genes were selected and identified by sequence analysis, followed by reverse transcription-PCR displaying the specific gene expression profiles in time. Functional grouping of the expressed genes indicated a correlation between colonization of the plants and an increase in expressed pathogenicity-related genes. This study indicates that lettuce plants respond to the presence of S. enterica serovar Dublin at physiological and molecular levels, as shown by the reduction in growth and the concurrent expression of pathogenicity-related genes. In addition, it was confirmed that Salmonella spp. can colonize the interior of lettuce plants, thus potentially imposing a human health risk when processed and consumed.

Building Early Learning Leaders: New Jersey's PreK-3rd Leadership Training. A Case Study

ERIC Educational Resources Information Center

Rice, Cynthia; Costanza, Vincent

2011-01-01

New Jersey school administrators are finding themselves in need of the supports necessary to build on the state's existing model preschools toward a broader vision of early learning, including making strong connections to the early learning system. Clearly, changing the educational mindset and building the related capacity of front-line leaders is…

School in the Park: Bridging Formal and Informal Learning Environments

ERIC Educational Resources Information Center

Mathison, Carla; Wachowiak, Susan; Feldman, Linda

2007-01-01

In San Diego, California, 800 public school students from the inner city are attending a program called School in the Park (SITP), for approximately one-fourth of their 3rd-, 4th-, and 5th-grade education. This unique program blends rigorous academic standards (formal learning) with hands-on, experiential curricula (informal learning), using…

Serovars, bacteriophage types and antimicrobial sensitivities associated with salmonellosis in dogs in the UK (1954-2012).

PubMed

Philbey, A W; Mather, H A; Gibbons, J F; Thompson, H; Taylor, D J; Coia, J E

2014-01-25

Serovars and bacteriophage (phage) types were determined for 442 isolates of Salmonella enterica from dogs in the UK submitted to the Scottish Salmonella Reference Laboratory from 1954 to 2012. The most frequent serovars were Salmonella Typhimurium (196 isolates; 44.3 per cent), Dublin (40 isolates; 9.0 per cent), Enteritidis (28 isolates; 6.3 per cent), Montevideo (19 isolates; 4.3 per cent), Virchow (10 isolates; 2.3 per cent), Heidelberg (8 isolates; 1.8 per cent) and Derby (8 isolates; 1.8 per cent), along with 55 other recognised serovars among 127 other isolates, and six incompletely classified isolates. Serovars were frequently represented by strains commonly associated with poultry, cattle or pigs and their products. Among 196 Salmonella Typhimurium isolates from dogs, the most frequent phage types (definitive types) were the multiple antimicrobial-resistant strains DT104 (62 isolates), DT204c (18 isolates) and DT193 (8 isolates), along with antimicrobial sensitive wild finch strains DT40 (13 isolates) and DT56 variant (8 isolates). Eleven of 28 isolates of Salmonella Enteritidis were phage type 4. S enterica was frequently recovered from faecal or intestinal samples of dogs with diarrhoea, although many dogs had concurrent infection with other enteric pathogens. Salmonella Dublin was recovered from the brain and/or cerebrospinal fluid of two dogs with meningoencephalitis. Salmonella Kedougou was isolated from the joint fluid of a dog with septic arthritis. Salmonella Typhimurium and Salmonella Dublin were each recovered from the vaginas of bitches that had aborted. Isolates of Salmonella Enteritidis phage types 1, 4 and 8, Salmonella Typhimurium DT104, Salmonella Dublin and Salmonella Indiana were isolated from clinically healthy dogs in households where the same strains were recovered from human beings with diarrhoea. The pattern ampicillin-chloramphenicol-spectinomycin-streptomycin-sulfamethoxazole-tetracycline (ACSpSSuT) was the most frequent resistance phenotype and was observed in 44 (13.3 per cent) of 330 isolates. Dogs in the UK are exposed to a wide variety of serovars of S enterica, sometimes associated with clinical disease, and represent a zoonotic risk.

3rd grade English language learners making sense of sound

NASA Astrophysics Data System (ADS)

Suarez, Enrique; Otero, Valerie

2013-01-01

Despite the extensive body of research that supports scientific inquiry and argumentation as cornerstones of physics learning, these strategies continue to be virtually absent in most classrooms, especially those that involve students who are learning English as a second language. This study presents results from an investigation of 3rd grade students' discourse about how length and tension affect the sound produced by a string. These students came from a variety of language backgrounds, and all were learning English as a second language. Our results demonstrate varying levels, and uses, of experiential, imaginative, and mechanistic reasoning strategies. Using specific examples from students' discourse, we will demonstrate some of the productive aspects of working within multiple language frameworks for making sense of physics. Conjectures will be made about how to utilize physics as a context for English Language Learners to further conceptual understanding, while developing their competence in the English language.

Injection of new psychoactive substance snow blow associated with recently acquired HIV infections among homeless people who inject drugs in Dublin, Ireland, 2015.

PubMed

Giese, Coralie; Igoe, Derval; Gibbons, Zorina; Hurley, Caroline; Stokes, Siobhan; McNamara, Sinead; Ennis, Orla; O'Donnell, Kate; Keenan, Eamon; De Gascun, Cillian; Lyons, Fiona; Ward, Mary; Danis, Kostas; Glynn, Ronan; Waters, Allison; Fitzgerald, Margaret

2015-01-01

In February 2015, an outbreak of recently acquired HIV infections among people who inject drugs (PWID) was identified in Dublin, following similar outbreaks in Greece and Romania in 2011. We compared drug and risk behaviours among 15 HIV cases and 39 controls. Injecting a synthetic cathinone, snow blow, was associated with recent HIV infection (AOR: 49; p=0.003). Prevention and control efforts are underway among PWID in Dublin, but may also be needed elsewhere in Europe.

Bug Distribution and Pattern Classification.

DTIC Science & Technology

1985-07-15

Center Educational Psychology University of Leyden San Diego. CA 92152 Urbana. IL 61801 Education Research Center oernaavelaan 2 Dr. Erling B. Andersen...Dr. Dattprasad rlivgi 23314 EN Leyden Department of Statistics Syracuse University The NETHERLANDS 3tudiestraede 6 Department of Psychology 1455...Rebecca Hetter Learning R&D Center Navy Personnel R&D Center University of Pittsburgh Ms. Kathleen Moreno Code 62 Pittsburgh, PA 15260 Navy Personnel R

Adaptive Training and Education Research at the US Army Research Laboratory: Bibliography (2013-2015)

DTIC Science & Technology

2016-03-01

US); 2014. ISBN 978-0-9893923-2-7. Goldberg, B. Chapter 9: Metacognitive supports to drive self -regulated learning experiences. In: Sottilare R...Presented at Metacognition and Self -Regulated Learning: Preparing Individuals through Learning How to Learn Workshop, 11th Annual International Conference... metacognition in the UrbanSim open-ended learning environment. In: Sottilare R, Sinatra A, editors. Proceedings of the 3rd Annual Approved for public release

Space Radar Image of Dublin, Ireland

NASA Image and Video Library

1999-04-15

This radar image of Dublin, Ireland, shows how the radar distinguishes between densely populated urban areas and nearby areas that are relatively unsettled. In the center of the image is the city natural harbor along the Irish Sea.

Hydrogeology and water quality of the Dublin and Midville aquifer systems at Waynesboro, Burke County, Georgia, 2011

USGS Publications Warehouse

Gonthier, Gerard

2013-01-01

The hydrogeology and water quality of the Dublin and Midville aquifer systems were characterized in the City of Waynesboro area in Burke County, Georgia, based on geophysical and drillers’ logs, flowmeter surveys, a 24-houraquifer test, and the collection and chemical analysis of water samples in a newly constructed well. At the test site, the Dublin aquifer system consists of interlayered sands and clays between depths of 396 and 691 feet, and the Midville aquifer system consists of a sandy clay layer overlying a sand and gravel layer between depths of 728 and 936 feet. The new well was constructed with three screened intervals in the Dublin aquifer system and four screened intervals in the Midville aquifer system. Wellbore-flowmeter testing at a pumping rate of 1,000 gallons per minute indicated that 52.2 percent of the total flow was from the shallower Dublin aquifer system with the remaining 47.8 percent from the deeper Midville aquifer system. The lower part of the lower Midville aquifer (900 to 930 feet deep), contributed only 0.1 percent of the total flow. Hydraulic properties of the two aquifer systems were estimated using data from two wellbore-flowmeter surveys and a 24-hour aquifer test. Estimated values of transmissivity for the Dublin and Midville aquifer systems were 2,000 and 1,000 feet squared per day, respectively. The upper and lower Dublin aquifers have a combined thickness of about 150 feet and the horizontal hydraulic conductivity of the Dublin aquifer system averages 10 feet per day. The upper Midville aquifer, lower Midville confining unit, and lower Midville aquifer have a combined thickness of about 210 feet, and the horizontal hydraulic conductivity of the Midville aquifer system averages 6 feet per day. Storage coefficient of the Dublin aquifer system, computed using the Theis method on water-level data from one observation well, was estimated to be 0.0003. With a thickness of about 150 feet, the specific storage of the Dublin aquifer system averages about 2×10-6 per foot. Water quality of the Dublin and Midville aquifer systems was characterized during the aquifer test on the basis of water samples collected from composite well flow originating from five depths in the completed production well during the aquifer test. Samples were analyzed for total dissolved solids, specific conductance, pH, alkalinity, and major ions. Water-quality results from composite samples, known flow contribution from individual screens, and a mixing equation were used to calculate water-quality values for sample intervals between sample depths or below the bottom sample depth. With the exception of iron and manganese, constituent concentrations of water from each of the sampled intervals and total flow from the well were within U.S. Environmental Protection Agency primary and secondary drinking-water standards. Water from the bottommost sample interval in the lower part of the lower Midville aquifer (900 to 930 feet) contained manganese and iron concentrations of 59.1 and 1,160 micrograms per liter, respectively, which exceeded secondary drinking-water standards. Because this interval contributed only 0.1 percent of the total flow to the well, water quality of this interval had little effect on the composite well water quality. Two other sample intervals from the Midville aquifer system and the total flow from both aquifer systems contained iron concentrations that slightly exceeded the secondary drinking-water standard of 300 micrograms per liter.

Can 18-Month-Old Infants Learn Words by Listening in on Conversations?

ERIC Educational Resources Information Center

Floor, Penelope; Akhtar, Nameera

2006-01-01

Previous research has shown that children as young as 2 can learn words from 3rd-party conversations (Akhtar, Jipson, & Callanan, 2001). The focus of this study was to determine whether younger infants could learn a new word through overhearing. Novel object labels were introduced to 18-month-old infants in 1 of 2 conditions: directly by an…

Beyond Course Availability: An Investigation into Order and Concurrency Effects of Undergraduate Programming Courses on Learning.

ERIC Educational Resources Information Center

Urbaczewski, Andrew; Urbaczewski, Lise

The objective of this study was to find the answers to two primary research questions: "Do students learn programming languages better when they are offered in a particular order, such as 4th generation languages before 3rd generation languages?"; and "Do students learn programming languages better when they are taken in separate semesters as…

Dynamic Assessment of Algebraic Learning in Predicting Third Graders’ Development of Mathematical Problem Solving

PubMed Central

Fuchs, Lynn S.; Compton, Donald L.; Fuchs, Douglas; Hollenbeck, Kurstin N.; Craddock, Caitlin F.; Hamlett, Carol L.

2008-01-01

Dynamic assessment (DA) involves helping students learn a task and indexing responsiveness to that instruction as a measure of learning potential. The purpose of this study was to explore the utility of a DA of algebraic learning in predicting 3rd graders’ development of mathematics problem solving. In the fall, 122 3rd-grade students were assessed on language, nonverbal reasoning, attentive behavior, calculations, word-problem skill, and DA. On the basis of random assignment, students received 16 weeks of validated instruction on word problems or received 16 weeks of conventional instruction on word problems. Then, students were assessed on word-problem measures proximal and distal to instruction. Structural equation measurement models showed that DA measured a distinct dimension of pretreatment ability and that proximal and distal word-problem measures were needed to account for outcome. Structural equation modeling showed that instruction (conventional vs. validated) was sufficient to account for math word-problem outcome proximal to instruction; by contrast, language, pretreatment math skill, and DA were needed to forecast learning on word-problem outcomes more distal to instruction. Findings are discussed in terms of responsiveness-to-intervention models for preventing and identifying learning disabilities. PMID:19884957

Bioethicsing.

PubMed

Arawi, Thalia; Mikati, Diana

2017-04-01

This article describes the components of a unique 9 month required course in bioethics for 3rd year medical students at the American University of Beirut. The blended (hybrid) learning format emphasizes three innovative learning activities: the bioethics documentary, edutainment games, and the bioethics log book. Sample student responses are included as well as an outline of limitations.

Developing clinical scenarios from a European perspective: successes and challenges.

PubMed

Wiseman, Allison; Horton, Khim

2011-10-01

This paper presents developmental work involving students from the University College Dublin (UCD), Ireland (n=9), University of Surrey, England (n=8) and University of Ljubljana and University of Maribor, Slovenia (n=5) participating in the Erasmus Intensive Programme. The Erasmus programme offers a two week 'Summer School' in the Faculty of Health Sciences, University of Maribor, Slovenia. Using a participatory approach, facilitators from both the UCD and Surrey engaged with students from all of the universities to develop scenarios for simulated learning experiences, in the care of older people, for utilisation on an e learning facility and within the simulated clinical learning environment. Students developed key transferable skills in learning, such as information literacy, cultural diversity, team working, communication, and clinical skills acquisition whilst exploring differences in healthcare delivery in other European countries. Copyright © 2011 Elsevier Ltd. All rights reserved.

Capturing the Complexity: Content, Type, and Amount of Instruction and Quality of the Classroom Learning Environment Synergistically Predict Third Graders' Vocabulary and Reading Comprehension Outcomes

ERIC Educational Resources Information Center

Connor, Carol McDonald; Spencer, Mercedes; Day, Stephanie L.; Giuliani, Sarah; Ingebrand, Sarah W.; McLean, Leigh; Morrison, Frederick J.

2014-01-01

We examined classrooms as complex systems that affect students' literacy learning through interacting effects of content and amount of time individual students spent in literacy instruction along with the global quality of the classroom learning environment. We observed 27 3rd-grade classrooms serving 315 target students using 2 different…

Forum 76; a Modern Chautauqua. Proceedings of the National Conference on Open Learning and Nontraditional Study (3rd, Lincoln, Nebraska, June 15-17, 1976).

ERIC Educational Resources Information Center

Cavert, C. Edward, Comp.

This third national conference on open learning and nontraditional study attempted to demonstrate cooperative efforts across the country and to show how open learning and nontraditional study relate to unified efforts to achieve common goals. Topics discussed at the conference included: (1) the national overview, (2) military training programs,…

Fraction Interventions for Students Struggling to Learn Mathematics: A Research Synthesis

ERIC Educational Resources Information Center

Shin, Mikyung; Bryant, Diane Pedrotty

2015-01-01

This study synthesized intervention studies focusing on instruction to improve fraction skills. Seventeen studies met the inclusion criteria: being published in English-language peer-reviewed journals or dissertations between 1975 and 2014, and targeting 3rd- through 12th-grade students struggling to learn mathematics. From the "Common Core…

Learning Activities Parents Can Do with Their Children.

ERIC Educational Resources Information Center

Arizona State Dept. of Education, Phoenix.

Learning activities parents can do with their children are described. Descriptions of activities are organized according to three age ranges: kindergarten through 3rd grade, 4th through 6th grade, and 7th through 12th grade. Initial discussion concerns pointers for parents of kindergartners; 41 things schools expect children to do before they…

Data Drive These Coaches: Literacy Project Merges School Goals with Teachers' Learning Needs

ERIC Educational Resources Information Center

Ittner, Anne; Helman, Lori; Burns, Matthew; McComas, Jennifer

2015-01-01

Research highlights the importance of individualized approaches and coaching to ongoing professional learning (Darling-Hammond, Wei, Andree, Richardson, & Orphanos, 2009). The purpose of this article is to describe an initiative that set out to help all students become proficient readers by 3rd grade. It demonstrates how coaching can support…

The Universal House: Energy, Shelter & The California Indian. Activity Guide, 4th/5th Grade.

ERIC Educational Resources Information Center

California Energy Extension Service, Sacramento.

This activity guide links energy awareness with resource management and traditional California Indian cultures for the 3rd-6th grade span. The materials combine cooperative, hands-on activities with background information and learning extensions. The interdisciplinary lessons are built upon themes, concepts, and learning processes outlined in…

Metadata: Standards for Retrieving WWW Documents (and Other Digitized and Non-Digitized Resources)

NASA Astrophysics Data System (ADS)

Rusch-Feja, Diann

The use of metadata for indexing digitized and non-digitized resources for resource discovery in a networked environment is being increasingly implemented all over the world. Greater precision is achieved using metadata than relying on universal search engines and furthermore, meta-data can be used as filtering mechanisms for search results. An overview of various metadata sets is given, followed by a more focussed presentation of Dublin Core Metadata including examples of sub-elements and qualifiers. Especially the use of the Dublin Core Relation element provides connections between the metadata of various related electronic resources, as well as the metadata for physical, non-digitized resources. This facilitates more comprehensive search results without losing precision and brings together different genres of information which would otherwise be only searchable in separate databases. Furthermore, the advantages of Dublin Core Metadata in comparison with library cataloging and the use of universal search engines are discussed briefly, followed by a listing of types of implementation of Dublin Core Metadata.

Effect of the luxS gene on biofilm formation and antibiotic resistance by Salmonella serovar Dublin.

PubMed

Ju, Xiangyu; Li, Junjie; Zhu, Mengjiao; Lu, Zhaoxin; Lv, Fengxia; Zhu, Xiaoyu; Bie, Xiaomei

2018-05-01

Biofilms are communities of bacterial cells that serve to protect them from external adverse influences and enhance bacterial resistance to antibiotics and sanitizers. Here, we studied the regulatory effects of glucose and sodium chloride on biofilm formation in Salmonella serovar Dublin (S. Dublin). To analyze expression levels of the quorum sensing gene luxS, we created a luxS knockout mutant. Also, antimicrobial resistance, hydrophobicity and autoinducer-2 (AI-2) activity of both the wild-type (WT) and the mutant strain were investigated. Our results revealed that glucose was not essential for S. Dublin biofilm formation but had an inhibitory effect on biofilm formation when the concentration was over 0.1%. NaCl was found to be indispensable in forming biofilm, and it also exerted an inhibitory effect at high concentrations (>1.0%). Both the WT and the mutant strains displayed significant MIC growth after biofilm formation. An increase of up to 32,768 times in the resistance of S. Dublin in biofilm phonotype against antibiotic (ampicillin) compared to its planktonic phonotype was observed. However, S. Dublin luxS knockout mutant only showed slight differences compared to the WT strain in the antimicrobial tests although it displayed better biofilm-forming capacity than the WT strain. The mutant strain also exhibited higher hydrophobicity than the WT strain, which was a feature related to biofilm formation. The production of the quorum sensing autoinducer-2 (AI-2) was significantly lower in the mutant strain than in the WT strain since the LuxS enzyme, encoded by the luxS gene, plays an essential role in AI-2 synthesis. However, the limited biofilm-forming ability in the WT strain indicated AI-2 was not directly related to S. Dublin biofilm formation. Furthermore, gene expression analysis of the WT and mutant strains revealed upregulation of genes related to biofilm stress response and enhanced resistance in the luxS mutant strain, which may provide evidence for the regulatory role of the luxS gene in biofilm formation. Copyright © 2018 Elsevier Ltd. All rights reserved.

The perception of place and the 'origins of handedness' debate: towards a cognitive cartography of science in late-Victorian Dublin.

PubMed

O'Sullivan, Tanya

2015-01-01

In 1884, a medical paper entitled 'Consideration of the Structural and Acquisitional Elements in Dextral Pre-Eminence' penned by the Dublin physician George Sigerson, appeared in the Proceedings of the Royal Irish Academy. A number of years later, the Journal of the Anthropological Institute of Great Britain and Ireland presented a similar piece by Dublin anatomist Daniel John Cunningham, on the topic of 'Right-Handedness and Left-Brainedness'. For the late nineteenth-century scientific community, these articles represented two Dublin-based contributions to a long-running and wide-ranging debate on the origins of handedness. However, by building on the geographical premise that scientific knowledge bears the imprint of its location and that place matters in the way scientific claims come to be sanctioned, this paper probes, not merely an encounter with evolutionary science in the less well explored domain of fin de siècle Dublin, but more crucially, how these local reviews of manual dexterity were in part shaped by the scientists' differing perceptions of their city. By attending to the lives of Sigerson and Cunningham and focusing on the interplay between life-space, city-space and science, it underscores the critical role of place and space in the reception, circulation and mobilisation of scientific knowledge in the city. Copyright © 2015 Elsevier Ltd. All rights reserved.

Radar Image of Dublin, Ireland

NASA Image and Video Library

2017-12-08

Visualization Date 1994-04-11 This radar image of Dublin, Ireland, shows how the radar distingishes between densely populated urban areas and nearby areas that are relatively unsettled. In the center of the image is the city's natural harbor along the Irish Sea. The pinkish areas in the center are the densely populated parts of the city and the blue/green areas are the suburbs. The two ends of the Dublin Bay are Howth Point, the circular peninsula near the upper right side of the image, and Dun Laoghaire, the point to the south. The small island just north of Howth is called "Ireland's Eye," and the larger island, near the upper right corner of the image is Lambay Island. The yellow/green mountains in the lower left of the image (south) are the Wicklow Mountains. The large lake in the lower left, nestled within these mountains, is the Poulaphouca Reservoir along River Liffey. The River Liffey, the River Dodder and the Tolka River are the three rivers that flow into Dublin. The straight features west of the city are the Grand Canal and the three rivers are the faint lines above and below these structures. The dark X-shaped feature just to the north of the city is the Dublin International Airport. The image was acquired by the Spaceborne Imaging Radar-C/X-band Synthetic Aperture (SIR-C/X-SAR) when it flew aboard the space shuttle Endeavour on April 11, 1994. This area is centered at 53.3 degrees north latitude, 6.2 degrees west longitude. The area shown is approximately 55 kilometers by 42 kilometers (34 miles by 26 miles). The colors are assigned to different frequencies and polarizations of the radar as follows: Red is L-band horizontally transmitted, horizontally received; green is L-band vertically transmitted, vertically received; and blue is C-band vertically transmitted, vertically received. SIR-C/X-SAR, a joint mission of the German, Italian, and the United States space agencies, is part of NASA's Mission to Planet Earth. Credit: NASA/GSFC For more information go to: visibleearth.nasa.gov/view_rec.php?id=467

Transition to blended learning: experiences from the first year of our blended learning Bachelor of Nursing Studies programme.

PubMed

Sweeney, Mary-Rose; Kirwan, Anne; Kelly, Mary; Corbally, Melissa; O Neill, Sandra; Kirwan, Mary; Hourican, Susan; Matthews, Anne; Hussey, Pamela

2016-10-01

The School of Nursing at Dublin City University offered a new blended learning Bachelor of Nursing Studies programme in the academic year 2011. To document the experiences of the academic team making the transition from a face-to-face classroom-delivered programme to the new blended learning format. Academics who delivered the programme were asked to describe their experiences of developing the new programme via two focus groups. Five dominant themes were identified: Staff Readiness; Student Readiness; Programme Delivery and Student Engagement; Assessment of Module Learning Outcomes and Feedback; and Reflecting on the First Year and Thinking of the Future. Face-to-face tutorials were identified as very important to both academics and students. Reservations about whether migrating the programme to an online format encouraged students to engage in additional practices of plagiarism were expressed by some. Student ability/readiness to engage with technology-enhanced learning was an important determinant of their own success academically. In the field of nursing blended learning is a relatively new and emerging field which will require huge cultural shifts for staff and students alike.

"The Coat Traps All Your Body Heat": Heterogeneity as Fundamental to Learning

ERIC Educational Resources Information Center

Rosebery, Ann S.; Ogonowski, Mark; DiSchino, Mary; Warren, Beth

2010-01-01

This article explores heterogeneity as fundamental to learning. Inspired by Bakhtin's notion of heteroglossia, a design team consisting of an experienced classroom teacher and 2 researchers investigated how a class of 3rd and 4th graders came to understand disciplinary points of view on heat, heat transfer, and the particulate nature of matter.…

Effects of Integrating Multimedia into the Third Grade Mathematics Curriculum to Improve Student Learning

ERIC Educational Resources Information Center

Liu, Yuliang

2012-01-01

This project was designed to test Mayer's multimedia theory in an elementary school to improve students' mathematics learning for low-income children. The study designed and developed two multimedia mathematics experiments in 3rd grade: 9's multiplication experiment and geometric solids experiment. The two experimental lessons were implemented in…

Morphological Analysis in Learning to Read Pseudowords in Hebrew

ERIC Educational Resources Information Center

Bar-On, Amalia; Ravid, Dorit

2011-01-01

This paper examines the role of morphology in gradeschool children's learning to read nonpointed Hebrew. It presents two experiments testing the reading of morphologically based nonpointed pseudowords. One hundred seventy-one Hebrew-speaking children and adolescents in seven age/schooling groups (beginning and end of 2nd, 3rd, 4th, 7th, and 11th…

Personalized Messages That Promote Science Learning in Virtual Environments

ERIC Educational Resources Information Center

Moreno, Roxana; Mayer, Richard E.

2004-01-01

College students learned how to design the roots, stem, and leaves of plants to survive in five different virtual reality environments through an agent-based multimedia educational game. For each student, the agent used personalized speech (e.g., including I and you) or nonpersonalized speech (e.g., 3rd-person monologue), and the game was…

Safe Surgery Trainer

DTIC Science & Technology

2014-11-15

design, testing, and development. b) Prototype Development – Continue developing SST software, game -flow, and mechanics. Continue developing art...refined learning objectives into measurement outlines. Update IRB submissions, edit usability game play study, and update I/ITSEC IRB. Provide case...minimal or near zero. 9) Related Activities a) Presenting at the Design of Learning Games Community Workshop, at I/ITSEC, Wednesday, Dec 3 rd

An Inquiry-Based Augmented Reality Mobile Learning Approach to Fostering Primary School Students' Historical Reasoning in Non-Formal Settings

ERIC Educational Resources Information Center

Efstathiou, Irene; Kyza, Eleni A.; Georgiou, Yiannis

2018-01-01

This study investigated the contribution of a location-based augmented reality (AR) inquiry-learning environment in developing 3rd grade students' historical empathy and conceptual understanding. Historical empathy is an important element of historical thinking, which is considered to improve conceptual understanding and support the development of…

Six Differentiated Strategies for ESL Literacy for Birth to Third Grade Developmentally Disabled and Normal Students of Hispanic Heritage

ERIC Educational Resources Information Center

Jaramillo, James; Jaramillo, Olga

2013-01-01

When one effectively employs the strategies of exploratory-learning, wait-time, intervention, guided reading, meaning, and phonological-morphological-syntactical awareness-for infants and on up-to 3rd grade students-all-in a Montessori-like-learning-literacy-setting replete with semantical interactions with phonology, syllabology, morphology, and…

Identifying Psychometric Properties of the Social-Emotional Learning Skills Scale

ERIC Educational Resources Information Center

Esen-Aygun, Hanife; Sahin-Taskin, Cigdem

2017-01-01

This study aims to develop a comprehensive scale of social-emotional learning. After constructing a wide range of item pool and expertise evaluation, validity and reliability studies were carried out through using the data-set of 439 primary school students at 3rd and 4th grade levels. Exploratory and confirmatory factor analysis results revealed…

Mathvision: A Mobile Video Application for Math Teacher Noticing of Learning Progressions

ERIC Educational Resources Information Center

Lewis, Stephen T.; Chao, Theodore; Battista, Michael

2017-01-01

We report on the development and evaluation of MathVision, a mobile-application designed to develop Virtual Professional Learning Communities through asynchronous discussion about 2nd, 3rd, 4th, and 5th grade students' mathematical thinking. MathVision allows teachers to upload videos of problems solving sessions using Cognition Based Assessment…

Synthesis of Research Symposium at CLD's 33rd International Conference on Learning Disabilities: "Must Reads for 2011"

ERIC Educational Resources Information Center

Weiser, Beverly L.; Reed, Deborah K.; Kethley, Caroline I.; Mathes, Patricia G.

2012-01-01

In October 2011, Council for Learning Disabilities' (CLD's) research committee members (i.e., authors of this article) presented their "Must Reads" at the organization's 33rd Annual International Conference on Learning Disabilities. In this article, the presenters summarize a few of their selected articles and state why each article is a "Must…

The impact of goal setting and goal orientation on performance during a clerkship surgical skills training program.

PubMed

Gardner, Aimee K; Diesen, Diana L; Hogg, Deborah; Huerta, Sergio

2016-02-01

The purpose of this study was to integrate relevant goal-setting theory and to identify if trainees' goal orientations have an impact on the assigned goals-performance relationship. Trainees attended 1 of the 3 goal-training activities (do your best, performance, or learning goals) for knot tying (KT) and camera navigation (CN) during the 3rd-year clerkship rotation. Questionnaires and pretests and/or post-tests were completed. One twenty-seven 3rd-year medical students (age: 25 ± 2.6; 54% women) participated in the training program. Pretraining to post-training performance changes were significant for all groups on both tasks (P < .01), but the increase was significantly greater (P < .01) for the learning goals group (do your best: KTΔ = 2.14, CNΔ = 1.69; performance: KTΔ = 2.49, CNΔ = 2.24; learning: KTΔ = 3.04 CNΔ = 2.76). Correlations between goal orientations and improvement were examined, revealing a unique role of goal orientation for performance improvement. These data indicate that consideration of goal type and trainee goal orientation must be considered during curriculum development to maximize educational value. Copyright © 2016 Elsevier Inc. All rights reserved.

Principle Paradigms Revisiting the Dublin Core 1:1 Principle

ERIC Educational Resources Information Center

Urban, Richard J.

2012-01-01

The Dublin Core "1:1 Principle" asserts that "related but conceptually different entities, for example a painting and a digital image of the painting, are described by separate metadata records" (Woodley et al., 2005). While this seems to be a simple requirement, studies of metadata quality have found that cultural heritage…

From the Building to the Grid: An Energy Revolution and Modeling Challenge; Workshop Proceedings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kroposki, B.; Komomua, C.; O'Malley, M.

This report summarizes the workshop entitled: From the Building to the Grid: An Energy Revolution and Modeling Challenge. The first workshop was held May 1-2, 2012 on NREL's campus in Golden, Colorado. The second was held June 6-7, 2012 at the University College Dublin, in Dublin, Ireland.

Selections from the ABC 2017 Annual Conference, Dublin, Ireland: Finding a Pedagogical Pot o' Gold

ERIC Educational Resources Information Center

Whalen, D. Joel

2018-01-01

This article, the first of a two-part series, offers readers 13 teaching innovations debuted at the 2017 Association for Business Communication's annual conference in Dublin, Ireland. Assignment topics presented here include communication strategy and message-packaging skills, deep communication insights, and career and personal development.…

Work Now and in the Future--3. Proceedings from the Annual Conference for Business and Industry Representatives, Educators and Others Concerned with the Changing World of Work (3rd, Portland, Oregon, November 5-6, 1986).

ERIC Educational Resources Information Center

McClure, Larry; Cotton, Kathleen, Ed.

These proceedings of a conference, which focused on technology and communications in tomorrow's workplace, include the following: synopses of "Learning for Life: Increasing Awareness of Human Capabilities" and the follow-up session "Multiplying Intelligence: What Do We Know about Learning Styles?" (Dee Dickinson); "From Programmed Instruction to…

Development of the Learning Result of Innovation and Information Technology in Education Using CIPPA, for Third Year Students in the Bachelor of Education Program, Nakhon Phanom University

ERIC Educational Resources Information Center

Hanrin, Chanwit

2014-01-01

This research proposes (1) to develop the learning management plan for the Innovation and Information Technology in Education of the 3rd year students of the Bachelor of Education Program by using CIPPA effectively according to the criteria 75/75; (2) to study the effectiveness index of the learning management plan for the Innovation and…

Effects of Instructional Support within Constructivist Learning Environments for Elementary School Students' Understanding of "Floating and Sinking"

ERIC Educational Resources Information Center

Hardy, Ilonca; Jonen, Angela; Moller, Komelia; Stern, Elsbeth

2006-01-01

In a repeated measures design (pretest, posttest, 1-year follow-up) with 161 3rd-grade students, the authors compared 2 curricula on floating and sinking within constructivist learning environments, varying in instructional support. The 2 curricula differed in the sequencing of content and the teacher's cognitively structuring statements. At the…

Elementary School Teachers as "Targets and Agents of Change": Teachers' Learning in Interaction with Reform Science Curriculum

ERIC Educational Resources Information Center

Metz, Kathleen E.

2009-01-01

This article examines teachers' perspectives on the challenges of using a science reform curriculum, as well as their learning in interaction with the curriculum and parallel professional development program. As case studies, I selected 4 veteran teachers of 2nd or 3rd grade, with varying science backgrounds (including 2 with essentially none).…

Running to Achieve: Engaging Students in Literacy and Physical Activity through an After-School Learning Community

ERIC Educational Resources Information Center

Vanzandt, Christina

2011-01-01

The purpose of this participant-observation study is to describe rural, southern, 3rd-5th grade children's engagement in running and writing in an after-school learning community called "Running to Achieve." This study provides insights into links between physical activity and writing by using one to engage students in the other. Three…

Can Animations Effectively Substitute for Traditional Teaching Methods? Part II: Potential for Differentiated Learning

ERIC Educational Resources Information Center

Gregorius, Roberto Ma.; Santos, Rhodora; Dano, Judith B.; Gutierrez, Jose J.

2010-01-01

Animations were prepared using Adobe Flash MX and tested on elementary (3rd-5th grade) and secondary chemistry students. A pre- and post-test study was used to compare the learning gains of students who received the animations with those who received textbook reading time and discussion in class. The control and experimental groups were further…

A School-Randomized Clinical Trial of an Integrated Social-Emotional Learning and Literacy Intervention: Impacts after 1 School Year

ERIC Educational Resources Information Center

Jones, Stephanie M.; Brown, Joshua L.; Hoglund, Wendy L. G.; Aber, J. Lawrence

2010-01-01

Objective: To report experimental impacts of a universal, integrated school-based intervention in social-emotional learning and literacy development on change over 1 school year in 3rd-grade children's social-emotional, behavioral, and academic outcomes. Method: This study employed a school-randomized, experimental design and included 942…

Extract from an Interview of Sean O'Connor: 8 September 1986

ERIC Educational Resources Information Center

Mulcahy, D. G.; O'Sullivan, Denis

2014-01-01

The educational community appreciates the editors of "Irish Educational Studies" for making the Interview with Sean O'Connor, in Dublin, Ireland available to a wider audience in 2014. The interview was originally in Sean O'Connor's home in Dublin on 8 September 1986. By that time, O'Connor had retired as Secretary of the Department of…

C2-C6 background hydrocarbon concentrations monitored at a roof top and green park site, in Dublin City centre.

PubMed

O'Donoghue, R T; Broderick, B M

2007-09-01

A 5 week monitoring campaign was carried out in Dublin City centre, to establish which site gave a more accurate background city centre estimation: a roof-top or green field site. This background represented a conservative estimate of HC exposure in Dublin City centre, useful for quantifying health effects related to this form of pollution and also for establishing a local background relative to the four surrounding main roads when the wind direction is travelling towards each road with the background receptor upwind. Over the entire monitoring campaign, the lowest concentrations and relative standard deviations were observed at the green field site, regardless of time of day or meteorological effects.

Perception of medical undergraduate students about interactive lectures in an outcome-based integrated curriculum: A cross-sectional study

PubMed Central

Asad, Mohammad Rehan; Amir, Khwaja; Tadvi, Naser Ashraf; Afzal, Kamran; Sami, Waqas; Irfan, Abdul

2017-01-01

OBJECTIVE: The objective of this study is to explore the student's perspectives toward the interactive lectures as a teaching and learning method in an integrated curriculum. MATERIALS AND METHODS: This cross-sectional study was conducted among 1st, 2nd and 3rd year male medical students (n = 121). A self-administered questionnaire based on the Visual, Auditory, Reader, Kinesthetic learning styles, learning theories, and role of feedback in teaching and learning on five-point Likert rating scale was used. The questionnaire was constructed after extensive literature review. RESULTS: There was an 80% response rate in this study. The total number of undergraduate medical students responded in the study were n = 97, 34 students of 1st year, n = 30 students of 2nd year and n = 33 student were in 3rd year, the mean scores of the student responses were calculated using Independent samples Kruskal–Wallis. There was no significant difference in the responses of the students of different years except for the question “The Interactive lectures facilitate effective use of learning resources.” Which showed significant difference in the responses of the 3 years students by Independent samples Kruskal–Wallis test. No significant association was found between the year of study and items of the questionnaire except for the same item, “ The Interactive lectures facilitates effective use of learning resources” by Spearman rank correlation test. CONCLUSION: The students perceive interactive lecture as an effective tool for facilitating visual and auditory learning modes, and for achieving curricular strategies. The student find the feedback given during the interactive lectures is effective in modifying learning attitude and enhancing motivation toward learning. PMID:29296601

Perception of medical undergraduate students about interactive lectures in an outcome-based integrated curriculum: A cross-sectional study.

PubMed

Asad, Mohammad Rehan; Amir, Khwaja; Tadvi, Naser Ashraf; Afzal, Kamran; Sami, Waqas; Irfan, Abdul

2017-01-01

The objective of this study is to explore the student's perspectives toward the interactive lectures as a teaching and learning method in an integrated curriculum. This cross-sectional study was conducted among 1 st , 2 nd and 3 rd year male medical students ( n = 121). A self-administered questionnaire based on the Visual, Auditory, Reader, Kinesthetic learning styles, learning theories, and role of feedback in teaching and learning on five-point Likert rating scale was used. The questionnaire was constructed after extensive literature review. There was an 80% response rate in this study. The total number of undergraduate medical students responded in the study were n = 97, 34 students of 1 st year, n = 30 students of 2 nd year and n = 33 student were in 3 rd year, the mean scores of the student responses were calculated using Independent samples Kruskal-Wallis. There was no significant difference in the responses of the students of different years except for the question "The Interactive lectures facilitate effective use of learning resources." Which showed significant difference in the responses of the 3 years students by Independent samples Kruskal-Wallis test. No significant association was found between the year of study and items of the questionnaire except for the same item, " The Interactive lectures facilitates effective use of learning resources" by Spearman rank correlation test. The students perceive interactive lecture as an effective tool for facilitating visual and auditory learning modes, and for achieving curricular strategies. The student find the feedback given during the interactive lectures is effective in modifying learning attitude and enhancing motivation toward learning.

Early math matters: kindergarten number competence and later mathematics outcomes.

PubMed

Jordan, Nancy C; Kaplan, David; Ramineni, Chaitanya; Locuniak, Maria N

2009-05-01

Children's number competencies over 6 time points, from the beginning of kindergarten to the middle of 1st grade, were examined in relation to their mathematics achievement over 5 later time points, from the end of 1st grade to the end of 3rd grade. The relation between early number competence and mathematics achievement was strong and significant throughout the study period. A sequential process growth curve model showed that kindergarten number competence predicted rate of growth in mathematics achievement between 1st and 3rd grades as well as achievement level through 3rd grade. Further, rate of growth in early number competence predicted mathematics performance level in 3rd grade. Although low-income children performed more poorly than their middle-income counterparts in mathematics achievement and progressed at a slower rate, their performance and growth were mediated through relatively weak kindergarten number competence. Similarly, the better performance and faster growth of children who entered kindergarten at an older age were explained by kindergarten number competence. The findings show the importance of early number competence for setting children's learning trajectories in elementary school mathematics. Copyright 2009 APA, all rights reserved

Early Math Matters: Kindergarten Number Competence and Later Mathematics Outcomes

PubMed Central

Jordan, Nancy C.; Kaplan, David; Ramineni, Chaitanya; Locuniak, Maria N.

2009-01-01

Children’s number competencies over 6 time points, from the beginning of kindergarten to the middle of 1st grade, were examined in relation to their mathematics achievement over 5 later time points, from the end of 1st grade to the end of 3rd grade. The relation between early number competence and mathematics achievement was strong and significant throughout the study period. A sequential process growth curve model showed that kindergarten number competence predicted rate of growth in mathematics achievement between 1st and 3rd grades as well as achievement level through 3rd grade. Further, rate of growth in early number competence predicted mathematics performance level in 3rd grade. Although low-income children performed more poorly than their middle-income counterparts in mathematics achievement and progressed at a slower rate, their performance and growth were mediated through relatively weak kindergarten number competence. Similarly, the better performance and faster growth of children who entered kindergarten at an older age were explained by kindergarten number competence. The findings show the importance of early number competence for setting children’s learning trajectories in elementary school mathematics. PMID:19413436

Stimulus modality and working memory performance in Greek children with reading disabilities: additional evidence for the pictorial superiority hypothesis.

PubMed

Constantinidou, Fofi; Evripidou, Christiana

2012-01-01

This study investigated the effects of stimulus presentation modality on working memory performance in children with reading disabilities (RD) and in typically developing children (TDC), all native speakers of Greek. It was hypothesized that the visual presentation of common objects would result in improved learning and recall performance as compared to the auditory presentation of stimuli. Twenty children, ages 10-12, diagnosed with RD were matched to 20 TDC age peers. The experimental tasks implemented a multitrial verbal learning paradigm incorporating three modalities: auditory, visual, and auditory plus visual. Significant group differences were noted on language, verbal and nonverbal memory, and measures of executive abilities. A mixed-model MANOVA indicated that children with RD had a slower learning curve and recalled fewer words than TDC across experimental modalities. Both groups of participants benefited from the visual presentation of objects; however, children with RD showed the greatest gains during this condition. In conclusion, working memory for common verbal items is impaired in children with RD; however, performance can be facilitated, and learning efficiency maximized, when information is presented visually. The results provide further evidence for the pictorial superiority hypothesis and the theory that pictorial presentation of verbal stimuli is adequate for dual coding.

Supporting 3rd-grade students model-based explanations about groundwater: a quasi-experimental study of a curricular intervention

NASA Astrophysics Data System (ADS)

Zangori, Laura; Vo, Tina; Forbes, Cory T.; Schwarz, Christina V.

2017-07-01

Scientific modelling is a key practice in which K-12 students should engage to begin developing robust conceptual understanding of natural systems, including water. However, little past research has explored primary students' learning about groundwater, engagement in scientific modelling, and/or the ways in which teachers conceptualise and cultivate model-based science learning environments. We are engaged in a multi-year project designed to support 3rd-grade students' formulation of model-based explanations (MBE) for hydrologic phenomenon, including groundwater, through curricular and instructional support. In this quasi-experimental comparative study of five 3rd-grade classrooms, we present findings from analysis of students' MBE generated as part of experiencing a baseline curricular intervention (Year 1) and a modelling-enhanced curricular intervention (Year 2). Findings show that students experiencing the latter version of the unit made significant gains in both conceptual understanding and reasoning about groundwater, but that these gains varied by classroom. Overall, student gains from Year 1 to Year 2 were attributed to changes in two of the five classrooms in which students were provided additional instructional supports and scaffolds to enhance their MBE for groundwater. Within these two classrooms, the teachers enacted the Year 2 curriculum in unique ways that reflected their deeper understanding about the practices of modelling. Their enactments played a critical role in supporting students' MBE about groundwater. Study findings contribute to research on scientific modelling in elementary science learning environments and have important implications for teachers and curriculum developers.

A proposal on teaching methodology: cooperative learning by peer tutoring based on the case method

NASA Astrophysics Data System (ADS)

Pozo, Antonio M.; Durbán, Juan J.; Salas, Carlos; del Mar Lázaro, M.

2014-07-01

The European Higher Education Area (EHEA) proposes substantial changes in the teaching-learning model, moving from a model based mainly on the activity of teachers to a model in which the true protagonist is the student. This new framework requires that students develop new abilities and acquire specific skills. This also implies that the teacher should incorporate new methodologies in class. In this work, we present a proposal on teaching methodology based on cooperative learning and peer tutoring by case study. A noteworthy aspect of the case-study method is that it presents situations that can occur in real life. Therefore, students can acquire certain skills that will be useful in their future professional practice. An innovative aspect in the teaching methodology that we propose is to form work groups consisting of students from different levels in the same major. In our case, the teaching of four subjects would be involved: one subject of the 4th year, one subject of the 3rd year, and two subjects of the 2nd year of the Degree in Optics and Optometry of the University of Granada, Spain. Each work group would consist of a professor and a student of the 4th year, a professor and a student of the 3rd year, and two professors and two students of the 2nd year. Each work group would have a tutoring process from each professor for the corresponding student, and a 4th-year student providing peer tutoring for the students of the 2nd and 3rd year.

Bioelectromagnetics 2005

DTIC Science & Technology

2006-08-14

fields in wound healing and nerve regeneration; 2) ultrashort high voltage pulses for tumor treatment; 3) therapeutic uses of magnetic fields; 4...7 Session 3: Role Of Electric Fields In Wound Healing And Nerve Regeneration (Continued)..........26 Session 4: Exposure...8 Bioelectromagnetics 2005, Dublin, Ireland Session 1: Role Of Electric Fields In Wound Healing And Nerve Regeneration Chairs: Richard

Boundary Crossing in R&D Projects in Schools: Learning through Cross-Professional Collaboration

ERIC Educational Resources Information Center

Schenke, Wouter; van Driel, Jan; Geijsel, Femke P.; Volman, Monique L. L.

2017-01-01

Background/Context: School leaders, teachers, and researchers are increasingly involved in collaborative research and development (R&D) projects in schools, which encourage crossing boundaries between the fields of school and research. It is not clear, however, what and how professionals in these projects learn through cross-professional…

"A Victim of Its Own Success"? The Diploma in Addiction Studies at Trinity College Dublin

ERIC Educational Resources Information Center

Woods, Marguerite; Butler, Shane

2011-01-01

This article reviews and reflects on the Diploma in Addiction Studies: a 1-year, full-time programme taught at the School of Social Work and Social Policy in Trinity College Dublin since the academic year 1983/1984, which has recently had its external funding withdrawn. The programme was aimed at multidisciplinary classes, including students from…

"The Problem of Trinity College Dublin": A Historical Perspective on Rationalisation in Higher Education in Ireland

ERIC Educational Resources Information Center

Walsh, John

2014-01-01

This paper offers a historical perspective on government policies for the rationalisation of higher education (HE) in Ireland through a critical re-appraisal of the initiative for "merger" of Trinity College and University College Dublin. The initiative launched by Donogh O'Malley in 1967 was the first significant attempt by an Irish…

Developing Online Tutorials to Improve Information Literacy Skills for Second-Year Nursing Students of University College Dublin

ERIC Educational Resources Information Center

Walters, Kirsteen; Bolich, Cecilia; Duffy, Daniel; Quinn, Ciarán; Walsh, Kathryn; Connolly, Sarah

2015-01-01

This article explores the process of developing online tutorials for a specified student group, in this case Second-Year Nursing students in University College Dublin. The product was commissioned by the Health Sciences Library and the UCD School of Nursing, Midwifery, and Health Systems. It was developed as a "Capstone Project" for part…

Quality of Family Life and Mortality in Seventeenth Century Dublin

ERIC Educational Resources Information Center

Jordan, Thomas E.

2010-01-01

Inquiry into the quality of family life in seventeenth century Dublin is an attempt to understand conditions in the second largest city in the British Isles; further, the era was one of convulsions in the body politic, social, and religious. The Scottish James I and VI (1556 1625) determined that the Irish province closest to Scotland, Ulster,…

The Dublin Dashboard: Design and Development of a Real-Time Analytical Urban Dashboard

NASA Astrophysics Data System (ADS)

McArdle, G.; Kitchin, R.

2016-09-01

As many cities increase in size across multiple dimensions such as population, economic output and physical size, new methods for understanding and managing cities are required. Data produced by and about urban environments offer insight into what is happening in cities. Real-time data from sensors within the city record current transport and environmental conditions such as noise levels, water levels, journey times and public transport delays. Similarly administrative data such as demographics, employment statistics, property prices and crime rates all provide insight into how a city is evolving. Traditionally, these data were maintained separately and managed by individual city departments. Advances in technology and a move to open-government have placed many of these data in the public domain. Urban dashboards have emerged as a technique to visualise these data in an accessible way. This paper describes the implementation of one such dashboard, the Dublin Dashboard, an interactive website which collects, analyses and visualises data from a variety of sources about Dublin in Ireland through a series of interactive maps, graphs and applications. This paper describes the approach, the data and the technology used to develop the Dublin Dashboard and acts as a guideline for developing urban dashboards in other cities.

ALT-C 96: Integrating Technology into the Curriculum. Conference Programme and Abstracts of the Association for Learning Technology Conference (3rd, Glasgow, Scotland, September 16-18, 1996).

ERIC Educational Resources Information Center

Cameron, Shona, Ed.

This program for the 1996 Association for Learning Technology Conference summarizes the poster sessions, discussions, workshops, and software demonstrations, and provides abstracts of the 38 papers presented. Topics covered by the papers include: hand-held technology for mathematics; modeling global warming; computer-mediated communications; Java;…

Professional Learning Communities Facilitator's Guide for the What Works Clearinghouse Practice Guide: Foundational Skills to Support Reading for Understanding in Kindergarten through 3rd Grade. REL 2016-277

ERIC Educational Resources Information Center

Kosanovich, Marcia; Foorman, Barbara

2016-01-01

The Regional Educational Laboratory (REL) Southeast developed a Professional Learning Community (PLC) Facilitators Guide to support educators in the implementation of recommendations from the What Works Clearinghouse's. The practice guide focuses on the foundational reading skills that enable students to read words, relate those words to their…

Determining an Effective Interactive Multimedia Arabic Language Courseware for Malaysian Primary School Children: An Alternative Paradigm for Learning in the Classroom

ERIC Educational Resources Information Center

Faryadi, Qais; Bakar, Zainab Abu; Maidinsah, Hamidah

2007-01-01

The prime purpose of this experimental research was to determine whether learning Arabic as a foreign language can be effectively enhanced through traditional methodology. As such, this research carefully investigated and critically analyzed the effectiveness of the traditional paradigm in teaching Arabic as a foreign language to 3rd grade primary…

FAA perspectives on historical wake turbulence R&D to recent operational implementations

DOT National Transportation Integrated Search

2017-06-03

A major intent of this presentation is to delineate why the many years of wake turbulence R&D are finally yielding beneficial operational implementations. It will highlight lessons learned from past R&D and going forward for NextGen and beyond.

An interactive learning environment for health care professionals.

PubMed Central

Cobbs, E.; Pincetl, P.; Silverman, B.; Liao, R. L.; Motta, C.

1994-01-01

This article summarizes experiences to date with building and deploying a clinical simulator that medical students use as part of a 3rd year primary care rotation. The simulated microworld helps students and health care professionals gain experience with and learn meta-cognitive skills for the care of complex patient populations that require treatment in the biopsychosocial-value dimensions. We explain lessons learned and next steps resulting from use of the program by over 300 users to date. PMID:7949975

Cognitive Risk Factors for Specific Learning Disorder: Processing Speed, Temporal Processing, and Working Memory.

PubMed

Moll, Kristina; Göbel, Silke M; Gooch, Debbie; Landerl, Karin; Snowling, Margaret J

2016-01-01

High comorbidity rates between reading disorder (RD) and mathematics disorder (MD) indicate that, although the cognitive core deficits underlying these disorders are distinct, additional domain-general risk factors might be shared between the disorders. Three domain-general cognitive abilities were investigated in children with RD and MD: processing speed, temporal processing, and working memory. Since attention problems frequently co-occur with learning disorders, the study examined whether these three factors, which are known to be associated with attention problems, account for the comorbidity between these disorders. The sample comprised 99 primary school children in four groups: children with RD, children with MD, children with both disorders (RD+MD), and typically developing children (TD controls). Measures of processing speed, temporal processing, and memory were analyzed in a series of ANCOVAs including attention ratings as covariate. All three risk factors were associated with poor attention. After controlling for attention, associations with RD and MD differed: Although deficits in verbal memory were associated with both RD and MD, reduced processing speed was related to RD, but not MD; and the association with RD was restricted to processing speed for familiar nameable symbols. In contrast, impairments in temporal processing and visuospatial memory were associated with MD, but not RD. © Hammill Institute on Disabilities 2014.

Towards a For-Profit University in Dublin: Another Brick in the Wall of Neo-Liberalism?

ERIC Educational Resources Information Center

Limond, David

2010-01-01

This article concerns the provision of for-profit higher education in the Republic of Ireland (RoI), particularly in Dublin. It briefly sketches the general development of university/college provision in the RoI and, more importantly, it describes certain aspects of the current state of play and makes a tentative prediction for the future--namely,…

The Museum of Irish Industry, Robert Kane and Education for All in the Dublin of the 1850s and 1860s

ERIC Educational Resources Information Center

Cullen, Clara

2009-01-01

The Museum of Irish Industry in Dublin, in its short existence (1845-1867) facilitated the access of ordinary people to popular scientific education, became a "cause celebre" and was defended by popular protest when the government recommended its abolition in 1862. Its Director, Sir Robert Kane (1809-1890) was not only an advocate of…

MLVA for Salmonella enterica subsp. enterica Serovar Dublin: Development of a Method Suitable for Inter-Laboratory Surveillance and Application in the Context of a Raw Milk Cheese Outbreak in France in 2012

PubMed Central

Vignaud, Marie-Léone; Cherchame, Emeline; Marault, Muriel; Chaing, Emilie; Le Hello, Simon; Michel, Valerie; Jourdan-Da Silva, Nathalie; Lailler, Renaud; Brisabois, Anne; Cadel-Six, Sabrina

2017-01-01

Salmonella enterica subspecies enterica serovar Dublin (S. Dublin) figures among the most frequently isolated Salmonella strains in humans in France. This serovar may affect production and animal health mainly in cattle herds with corresponding high economic losses. Given that the current gold standard method, pulsed-field gel electrophoresis (PFGE), provides insufficient discrimination for epidemiological investigations, we propose a standard operating procedure in this study for multiple-locus variable number tandem repeat analysis (MLVA) of S. Dublin, suitable for inter-laboratory surveillance. An in silico analysis on the genome of S. Dublin strains CT_02021853 was performed to identify appropriate microsatellite regions. Of 21 VNTR loci screened, six were selected and 401 epidemiologically unrelated and related strains, isolated from humans, food and animals were analyzed to assess performance criteria such as typeability, discriminatory power and epidemiological concordance. The MLVA scheme developed was applied to an outbreak involving Saint-Nectaire cheese for which investigations were conducted in France in 2012, making it possible to discriminate between epidemiologically related strains and sporadic case strains, while PFGE assigned only a single profile. The six loci selected were sequenced on a large set of strains to determine the sequence of the repeated units and flanking regions, and their stability was evaluated in vivo through the analysis of the strains investigated from humans, food and the farm environment during the outbreak. The six VNTR selected were found to be stable and the discriminatory power of the MLVA method developed was calculated to be 0.954 compared with that for PFGE, which was only 0.625. Twenty-four reference strains were selected from the 401 examined strains in order to represent most of the allele diversity observed for each locus. This reference set can be used to harmonize MLVA results and allow data exchange between laboratories. This original MLVA protocol could be used easily and routinely for monitoring of serovar Dublin isolates and for conducting outbreak investigations. PMID:28289408

Studying abroad inclusively: Reflections by college students with and without intellectual disability.

PubMed

Prohn, Seb M; Kelley, Kelly R; Westling, David L

2016-12-01

Postsecondary education programs have increased opportunities for students with and without intellectual disabilities to study abroad as inclusive classes. Using open-coding qualitative techniques, the authors examined an inclusive study abroad group's daily reflective journals during a study abroad trip to London and Dublin. Three shared categories emerged from analysis: personal development, bonding/social inclusion, and learning from English and Irish adults with intellectual disabilities. Each group reported two distinct categories as well. Students with intellectual disabilities described the importance of mobility/transportation and fun, while their classmates without intellectual disabilities described the importance of inclusive learning and an increasing awareness of barriers to full participation for people with disabilities. Student-constructed categories are used to describe the benefits of inclusive study abroad and build future inclusive international opportunities. © The Author(s) 2015.

Possible roles for fronto-striatal circuits in reading disorder

PubMed Central

Hancock, Roeland; Richlan, Fabio; Hoeft, Fumiko

2016-01-01

Several studies have reported hyperactivation in frontal and striatal regions in individuals with reading disorder (RD) during reading-related tasks. Hyperactivation in these regions is typically interpreted as a form of neural compensation and related to articulatory processing. Fronto-striatal hyperactivation in RD can however, also arise from fundamental impairment in reading related processes, such as phonological processing and implicit sequence learning relevant to early language acquisition. We review current evidence for the compensation hypothesis in RD and apply large-scale reverse inference to investigate anatomical overlap between hyperactivation regions and neural systems for articulation, phonological processing, implicit sequence learning. We found anatomical convergence between hyperactivation regions and regions supporting articulation, consistent with the proposed compensatory role of these regions, and low convergence with phonological and implicit sequence learning regions. Although the application of large-scale reverse inference to decode function in a clinical population should be interpreted cautiously, our findings suggest future lines of research that may clarify the functional significance of hyperactivation in RD. PMID:27826071

Characterization of Salmonella enterica isolates causing bacteremia in Lima, Peru, using multiple typing methods

PubMed Central

Betancor, Laura; García, Coralith; Astocondor, Lizeth; Hinostroza, Noemí; Bisio, Julieta; Rivera, Javier; Perezgasga, Lucía; Pérez Escanda, Victoria; Yim, Lucía; Jacobs, Jan; García-del Portillo, Francisco; Chabalgoity, José A.; Puente, José L.

2017-01-01

In this study, different molecular typing tools were applied to characterize 95 Salmonella enterica blood isolates collected between 2008 and 2013 from patients at nine public hospitals in Lima, Peru. Combined results of multiplex PCR serotyping, two- and seven-loci multilocus sequence typing (MLST) schemes, serotyping, IS200 amplification and RAPD fingerprints, showed that these infections were caused by eight different serovars: Enteritidis, Typhimurium, Typhi, Choleraesuis, Dublin, Paratyphi A, Paratyphi B and Infantis. Among these, Enteritidis, Typhimurium and Typhi were the most prevalent, representing 45, 36 and 11% of the isolates, respectively. Most isolates (74%) were not resistant to ten primarily used antimicrobial drugs; however, 37% of the strains showed intermediate susceptibility to ciprofloxacin (ISC). Antimicrobial resistance integrons were carried by one Dublin (dfra1 and aadA1) and two Infantis (aadA1) isolates. The two Infantis isolates were multidrug resistant and harbored a large megaplasmid. Amplification of spvC and spvRA regions showed that all Enteritidis (n = 42), Typhimurium (n = 34), Choleraesuis (n = 3) and Dublin (n = 1) isolates carried the Salmonella virulence plasmid (pSV). We conclude that the classic serotyping method can be substituted by the multiplex PCR and, when necessary, sequencing of only one or two loci of the MLST scheme is a valuable tool to confirm the results. The effectiveness and feasibility of different typing tools is discussed. PMID:29267322

The problem of seeing hospital staff without G.P. referral--the otolaryngological experience.

PubMed

Walshe, P; McGrain, S; Colgan, G; McShane, D

2001-01-01

Over a three month period, a record was kept of the number of hospital staff who approached the E.N.T. team requesting help for a medical problem. Staff members included doctors, nurses, clerical staff, paramedical staff and porters. The total number of employees in the hospital was recorded. The average General practitioner public patient list (General medical Service cardholders) for South Dublin was recorded (our hospital is in south west Dublin). The total number of hospital staff seen by E.N.T. in 3 months was seventy seven. The total number of hospital staff seen by other surgical specialties was approximately one hundred and sixty seven. Extrapolation of numbers seen by E.N.T. service in three months to numbers seen over a one year period is 308 patients. The numbers seen by the E.N.T. service in three months corresponds to 11.7% of the average South Dublin General Practitioner Medical card list. It has been estimated that approximately 20% of all problems the average General practitioner sees in a week are E.N.T. related. Those practices with a smaller paediatric population would have approximately 15% of the total practice concearned with E.N.T. problems. Therefore as 15% of 2,400 (total hospital staff) = 360, there is potentially a small General Practice which is 'hidden' within the hospital.

A Comparative Study of the Personality Characteristics of Primary-School Students with Learning Disabilities and Their Nonlearning Disabled Peers

ERIC Educational Resources Information Center

Gitanjali, Sharma

2004-01-01

This study examined the personality characteristics of 180 boys and girls of ages 8, 9, and 10 with learning disabilities (LD) in 3rd, 4th, and 5th grade in urban and rural primary schools of Andhrapradesh, India. The subjects were identified based on their scholastic achievement on a spelling dictation test, an oral reading test, a reading…

Professional Learning Communities Participant's Activities for the What Works Clearinghouse Practice Guide: Foundational Skills to Support Reading for Understanding in Kindergarten through 3rd Grade. REL 2016-277a

ERIC Educational Resources Information Center

Kosanovich, Marcia; Foorman, Barbara

2016-01-01

The Regional Educational Laboratory (REL) Southeast developed a Professional Learning Community (PLC) Facilitators Guide to support educators in the implementation of recommendations from the What Works Clearinghouse's. The practice guide focuses on the foundational reading skills that enable students to read words, relate those words to their…

The Effect of Teaching Methods and Learning Styles on Capabilities of Writing Essays on Elementary School's Students in East Jakarta

ERIC Educational Resources Information Center

Wuryani; Yufiarti

2017-01-01

The objective of this research was to discover the effect of teaching methods and learning styles on the student's ability to write essays. This study was conducted in elementary school in East Jakarta. The population of this studies was 3rd-grade elementary school students who study in East Jakarta. Samples were taken with stratified cluster…

Technological Innovation, Corporate R&D Alliances and Organizational Learning

DTIC Science & Technology

1995-01-01

public corporations . On the other hand, the questionnaire response bias was a potential problem. As explained in Section 4, the size and innovativeness...DISSERTATION RAND. " " .,’ Technological Innovation, Corporate R&D Alliances and Organizational Learning Wayne G. Walker RAND Graduate School... response , including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing

Evaluation of Alternative Conceptual Models Using Interdisciplinary Information: An Application in Shallow Groundwater Recharge and Discharge

NASA Astrophysics Data System (ADS)

Lin, Y.; Bajcsy, P.; Valocchi, A. J.; Kim, C.; Wang, J.

2007-12-01

Natural systems are complex, thus extensive data are needed for their characterization. However, data acquisition is expensive; consequently we develop models using sparse, uncertain information. When all uncertainties in the system are considered, the number of alternative conceptual models is large. Traditionally, the development of a conceptual model has relied on subjective professional judgment. Good judgment is based on experience in coordinating and understanding auxiliary information which is correlated to the model but difficult to be quantified into the mathematical model. For example, groundwater recharge and discharge (R&D) processes are known to relate to multiple information sources such as soil type, river and lake location, irrigation patterns and land use. Although hydrologists have been trying to understand and model the interaction between each of these information sources and R&D processes, it is extremely difficult to quantify their correlations using a universal approach due to the complexity of the processes, the spatiotemporal distribution and uncertainty. There is currently no single method capable of estimating R&D rates and patterns for all practical applications. Chamberlin (1890) recommended use of "multiple working hypotheses" (alternative conceptual models) for rapid advancement in understanding of applied and theoretical problems. Therefore, cross analyzing R&D rates and patterns from various estimation methods and related field information will likely be superior to using only a single estimation method. We have developed the Pattern Recognition Utility (PRU), to help GIS users recognize spatial patterns from noisy 2D image. This GIS plug-in utility has been applied to help hydrogeologists establish alternative R&D conceptual models in a more efficient way than conventional methods. The PRU uses numerical methods and image processing algorithms to estimate and visualize shallow R&D patterns and rates. It can provide a fast initial estimate prior to planning labor intensive and time consuming field R&D measurements. Furthermore, the Spatial Pattern 2 Learn (SP2L) was developed to cross analyze results from the PRU with ancillary field information, such as land coverage, soil type, topographic maps and previous estimates. The learning process of SP2L cross examines each initially recognized R&D pattern with the ancillary spatial dataset, and then calculates a quantifiable reliability index for each R&D map using a supervised machine learning technique called decision tree. This JAVA based software package is capable of generating alternative R&D maps if the user decides to apply certain conditions recognized by the learning process. The reliability indices from SP2L will improve the traditionally subjective approach to initiating conceptual models by providing objectively quantifiable conceptual bases for further probabilistic and uncertainty analyses. Both the PRU and SP2L have been designed to be user-friendly and universal utilities for pattern recognition and learning to improve model predictions from sparse measurements by computer-assisted integration of spatially dense geospatial image data and machine learning of model dependencies.

Dad Was a Terrible Hard Worker: The Influence of Family and School on Dublin's Men's Working Lives--Preliminary Findings. CLMS Working Paper.

ERIC Educational Resources Information Center

Goodwin, John

The influences that home, family, and education have on Irish men's experiences of working life are explored based on interviews and questionnaire research carried out in North Dublin during 1997 and 1998. A two-stage research design was adopted. The first stage involved a short attitudinal-type questionnaire given to men at a sporting club. The…

"Click Here to Order This Book": A Case Study of Print and Electronic Patron-Driven Acquisition in University College Dublin

ERIC Educational Resources Information Center

Tynan, Mark; McCarney, Eoin

2014-01-01

University College Dublin became the first library in the Republic of Ireland to trial patron-driven acquisition (PDA) as a collection development tool in 2013. A total of 42% of UCD Library's book budget was allocated to the project, which included both electronic and print books. This article describes the twelve month project from the tender…

The implications of renewable energy research and development: Policy scenario analysis with experience and learning effects

NASA Astrophysics Data System (ADS)

Kobos, Peter Holmes

This dissertation analyzes the current and potential future costs of renewable energy technology from an institutional perspective. The central hypothesis is that reliable technology cost forecasting can be achieved through standard and modified experience curves implemented in a dynamic simulation model. Additionally, drawing upon region-specific institutional lessons highlights the role of market, social, and political institutions throughout an economy. Socio-political influences and government policy pathways drive resource allocation decisions that may be predominately influenced by factors other than those considered in a traditional market-driven, mechanistic approach. Learning in economic systems as a research topic is an attractive complement to the notion of institutional pathways. The economic implications of learning by doing, as first outlined by Arrow (1962), highlight decreasing production costs as individuals, or more generally the firm, become more familiar with a production process. The standard approach in the literature has been to employ a common experience curve where cumulative production is the only independent variable affecting costs. This dissertation develops a two factor experience curve, adding research, development and demonstration (RD&D) expenditures as a second variable. To illustrate the concept in the context of energy planning, two factor experience curves are developed for wind energy technology and solar photovoltaic (PV) modules under different assumptions on learning rates for cumulative capacity and the knowledge stock (a function of past RD&D efforts). Additionally, a one factor experience curve and cost trajectory scenarios are developed for concentrated solar power and geothermal energy technology, respectively. Cost forecasts are then developed for all four of these technologies in a dynamic simulation model. Combining the theoretical framework of learning by doing with the fields of organizational learning and institutional economics, this dissertation argues that the current state of renewable energy technology costs is largely due to the past production efforts (learning by doing) and RD&D efforts (learning by searching) in these global industries. This cost pathway, however, may be altered through several policy process feedback mechanisms including targeted RD&D expenditures, maintenance of RD&D to promote learning effects, and financial incentive programs that support energy production from renewable energy technologies.

Data-driven heterogeneity in mathematical learning disabilities based on the triple code model.

PubMed

Peake, Christian; Jiménez, Juan E; Rodríguez, Cristina

2017-12-01

Many classifications of heterogeneity in mathematical learning disabilities (MLD) have been proposed over the past four decades, however no empirical research has been conducted until recently, and none of the classifications are derived from Triple Code Model (TCM) postulates. The TCM proposes MLD as a heterogeneous disorder, with two distinguishable profiles: a representational subtype and a verbal subtype. A sample of elementary school 3rd to 6th graders was divided into two age cohorts (3rd - 4th grades, and 5th - 6th grades). Using data-driven strategies, based on the cognitive classification variables predicted by the TCM, our sample of children with MLD clustered as expected: a group with representational deficits and a group with number-fact retrieval deficits. In the younger group, a spatial subtype also emerged, while in both cohorts a non-specific cluster was produced whose profile could not be explained by this theoretical approach. Copyright © 2017 Elsevier Ltd. All rights reserved.

R&D Alert. Volume 7, Number 2, 2005

ERIC Educational Resources Information Center

White, Noel, Ed.

2005-01-01

"R&D Alert" covers issues affecting schools in the Western Regional Educational Laboratory's four-state region--Arizona, California, Nevada, and Utah--and throughout the United States. This issue of "R&D Alert" shares what WestEd is learning from a sample of their latest work, focusing on three points in the process:…

Effects of Data Sampling on Graphical Depictions of Learning

ERIC Educational Resources Information Center

Carey, Mary-Katherine; Bourret, Jason C.

2014-01-01

Continuous and discontinuous data-collection methods were compared in the context of discrete-trial programming. Archival data sets were analyzed using trial sampling (1st 5 trials, 1st 3 trials, and 1st trial only) and session sampling (every other session, every 3rd session, and every 5th session). Results showed that trial sampling…

What's in a Domain: Understanding How Students Approach Questioning in History and Science

ERIC Educational Resources Information Center

Portnoy, Lindsay Blau; Rabinowitz, Mitchell

2014-01-01

How students ask questions as they learn has implications for understanding, retention, and problem solving. The current research investigates the influence of domain, age, and previous experience with content on the ways students approach questioning across history and science texts. In 3 experiments, 3rd-, 8th-, and 10th-grade students in large…

The effects of light emitting diode therapy following high intensity exercise.

PubMed

Denis, Romain; O'Brien, Christopher; Delahunt, Eamonn

2013-05-01

To determine the effects of light emitting diode therapy (LEDT) irradiation on blood lactate concentration ([La]) clearance, peak power output and fatigue index (FI) following high intensity fatiguing exercise. Single-blinded randomised cross-over placebo controlled trial. University College Dublin, Institute for Sport and Health, Human performance laboratory. Eighteen healthy male athletes were recruited from field-based sports (including soccer, hockey and rugby union) and participated in the present study. Dependent variables were the peak power output elicited during the Wingate Anaerobic Test (WAnT), FI and [La] before and after each exercise. WAnT performance was measured prior to high intensity fatiguing exercise (Yo-Yo IR2), prior to LEDT or placebo, and following LEDT or placebo. [La] was measured at baseline, immediately after the Yo-Yo IR2, and in the 3rd, 9th, and 15th min following LEDT or placebo condition. No significant group by treatment interactions were observed for any outcome measures (P > 0.05). We conclude that LEDT irradiation applied following high intensity exercise was not effective and has no immediate effect on [La] clearance, peak power and FI, and thus has no significant effect on muscle recovery in athletes at the intensity and irradiation parameters used in the present study. Further research using different parameters is required to determine how LEDT may contribute to post-exercise recovery. Copyright © 2012 Elsevier Ltd. All rights reserved.

Still Going Strong: A Tracer Study of the Community Mothers Programme, Dublin, Ireland. Early Childhood Development: Practice and Reflections. Following Footsteps.

ERIC Educational Resources Information Center

Molloy, Brenda

Home visiting is the strategy used by the Community Mothers Programme to enhance parenting skills of first-time mothers from economically disadvantaged areas in Dublin, Ireland. The home visitors are all women from the community who volunteer to visit parents in their homes once a month for 1 hour over a 12-month period. In a 1989 evaluation, 232…

An outbreak of Salmonella dublin infection in England and Wales associated with a soft unpasteurized cows' milk cheese.

PubMed

Maguire, H; Cowden, J; Jacob, M; Rowe, B; Roberts, D; Bruce, J; Mitchell, E

1992-12-01

An outbreak of Salmonella dublin infection occurred in England and Wales in October to December 1989. Forty-two people were affected, mainly adults, and most lived in south-east England. Microbiological and epidemiological investigations implicated an imported Irish soft unpasteurized cows' milk cheese as the vehicle of infection. A case-control study showed a statistically significant association between infection and consumption of the suspect cheese (p = 0.001). Salmonella dublin was subsequently isolated from cheeses obtained from the manufacturer's premises. Initial control measures included the withdrawal of the cheese from retail sale and a Food Hazard Warning to Environmental Health Departments, as well as a press release, from the Department of Health. Subsequently, a decision was taken by the manufacturer to pasteurize milk used in the production of cheese for the UK market and importation of the cheese resumed in June 1990.

An outbreak of Salmonella dublin infection in England and Wales associated with a soft unpasteurized cows' milk cheese.

PubMed Central

Maguire, H.; Cowden, J.; Jacob, M.; Rowe, B.; Roberts, D.; Bruce, J.; Mitchell, E.

1992-01-01

An outbreak of Salmonella dublin infection occurred in England and Wales in October to December 1989. Forty-two people were affected, mainly adults, and most lived in south-east England. Microbiological and epidemiological investigations implicated an imported Irish soft unpasteurized cows' milk cheese as the vehicle of infection. A case-control study showed a statistically significant association between infection and consumption of the suspect cheese (p = 0.001). Salmonella dublin was subsequently isolated from cheeses obtained from the manufacturer's premises. Initial control measures included the withdrawal of the cheese from retail sale and a Food Hazard Warning to Environmental Health Departments, as well as a press release, from the Department of Health. Subsequently, a decision was taken by the manufacturer to pasteurize milk used in the production of cheese for the UK market and importation of the cheese resumed in June 1990. PMID:1468523

A full XML-based approach to creating hypermedia learning modules in web-based environments: application to a pathology course.

PubMed

Staccini, Pascal; Dufour, Jean -Charles; Joubert, Michel; Michiels, Jean -François; Fieschi, Marius

2003-01-01

Nowadays, web-based learning services are a key topic in the pedagogical and learning strategies of universities. While organisational and teaching requirements of the learning environment are being evaluated, technical specifications are emerging, enabling educators to build advanced "units of learning". Changes, however, take a long time and cost-effective solutions have to be found to involve our institutions in such actions. In this paper, we present a model of the components of a course. We detail the method followed to implement this model in hypermedia modules with a viewer that can be played on line or from a CD-ROM. The XML technology has been used to implement all the data structures and a client-side architecture has been designed to build a course viewer. Standards of description of content (such as Dublin Core and DocBook) have been integrated into the data structures. This tool has been populated with data from a pathology course and supports other medical contents. The choice of the architecture and the usefulness of the programming tools are discussed. The means of migrating towards a server-side application are presented.

Smoking characteristics of Polish immigrants in Dublin.

PubMed

Kabir, Zubair; Clarke, Vanessa; Keogan, Sheila; Currie, Laura M; Zatonski, Witold; Clancy, Luke

2008-12-31

This study examined two main hypotheses: a) Polish immigrants' smoking estimates are greater than their Irish counterparts (b) Polish immigrants purchasing cigarettes from Poland smoke "heavier" (>/= 20 cigarettes a day) when compared to those purchasing cigarettes from Ireland. The study also set out to identify significant predictors of 'current' smoking (some days and everyday) among the Polish immigrants. Dublin residents of Polish origin (n = 1,545) completed a previously validated Polish questionnaire in response to an advertisement in a local Polish lifestyle magazine over 5 weekends (July-August, 2007). The Office of Tobacco Control telephone-based monthly survey data were analyzed for the Irish population in Dublin for the same period (n = 484). Age-sex adjusted smoking estimates were: 47.6% (95% Confidence Interval [CI]: 47.3%; 48.0%) among the Poles and 27.8% (95% CI: 27.2%; 28.4%) among the general Irish population (p < 0.001). Of the 57% of smokers (n = 345/606) who purchased cigarettes solely from Poland and the 33% (n = 198/606) who purchased only from Ireland, 42.6% (n = 147/345) and 41.4% (n = 82/198) were "heavy" smokers, respectively (p = 0.79). Employment (Odds Ratio [OR]: 2.89; 95% CI: 1.25-6.69), lower education (OR: 3.76; 95%CI: 2.46-5.74), and a longer stay in Ireland (>24 months) were significant predictors of current smoking among the Poles. An objective validation of the self-reported smoking history of a randomly selected sub-sample immigrant group, using expired carbon monoxide (CO) measurements, showed a highly significant correlation coefficient (r = 0.64) of expired CO levels with the reported number of cigarettes consumed (p < 0.0001). Polish immigrants' smoking estimates are higher than their Irish counterparts, and particularly if employed, with only primary-level education, and are overseas >2 years.

Exploring Cultural Heritage Resources in a 3d Collaborative Environment

NASA Astrophysics Data System (ADS)

Respaldiza, A.; Wachowicz, M.; Vázquez Hoehne, A.

2012-06-01

Cultural heritage is a complex and diverse concept, which brings together a wide domain of information. Resources linked to a cultural heritage site may consist of physical artefacts, books, works of art, pictures, historical maps, aerial photographs, archaeological surveys and 3D models. Moreover, all these resources are listed and described by a set of a variety of metadata specifications that allow their online search and consultation on the most basic characteristics of them. Some examples include Norma ISO 19115, Dublin Core, AAT, CDWA, CCO, DACS, MARC, MoReq, MODS, MuseumDat, TGN, SPECTRUM, VRA Core and Z39.50. Gateways are in place to fit in these metadata standards into those used in a SDI (ISO 19115 or INSPIRE), but substantial work still remains to be done for the complete incorporation of cultural heritage information. Therefore, the aim of this paper is to demonstrate how the complexity of cultural heritage resources can be dealt with by a visual exploration of their metadata within a 3D collaborative environment. The 3D collaborative environments are promising tools that represent the new frontier of our capacity of learning, understanding, communicating and transmitting culture.

Joint Machine Learning and Game Theory for Rate Control in High Efficiency Video Coding.

PubMed

Gao, Wei; Kwong, Sam; Jia, Yuheng

2017-08-25

In this paper, a joint machine learning and game theory modeling (MLGT) framework is proposed for inter frame coding tree unit (CTU) level bit allocation and rate control (RC) optimization in High Efficiency Video Coding (HEVC). First, a support vector machine (SVM) based multi-classification scheme is proposed to improve the prediction accuracy of CTU-level Rate-Distortion (R-D) model. The legacy "chicken-and-egg" dilemma in video coding is proposed to be overcome by the learning-based R-D model. Second, a mixed R-D model based cooperative bargaining game theory is proposed for bit allocation optimization, where the convexity of the mixed R-D model based utility function is proved, and Nash bargaining solution (NBS) is achieved by the proposed iterative solution search method. The minimum utility is adjusted by the reference coding distortion and frame-level Quantization parameter (QP) change. Lastly, intra frame QP and inter frame adaptive bit ratios are adjusted to make inter frames have more bit resources to maintain smooth quality and bit consumption in the bargaining game optimization. Experimental results demonstrate that the proposed MLGT based RC method can achieve much better R-D performances, quality smoothness, bit rate accuracy, buffer control results and subjective visual quality than the other state-of-the-art one-pass RC methods, and the achieved R-D performances are very close to the performance limits from the FixedQP method.

David Gordon Campbell Robertson: A Biographical Sketch

NASA Astrophysics Data System (ADS)

See, J. B.

Emeritus Professor David Robertson of the Missouri University of Science and Technology was born in Dublin Ireland on 29 December 1941. His father was a merchant navy Captain who served during WWII and during David's early years his family lived in Dublin and Donegal where David went to the local elementary school. In 1954 he moved to London with his parents and attended Highgate School before commencing metallurgy at the Royal School of Mines, Imperial College, London in 1960.

Pathogen translocation and histopathological lesions in an experimental model of Salmonella Dublin infection in calves receiving lactic acid bacteria and lactose supplements

PubMed Central

Zbrun, María V.; Soto, Lorena P.; Bertozzi, Ezequiel; Sequeira, Gabriel J.; Marti, Luis E.; Signorini, Marcelo L.; Armesto, Roberto Rodríguez; Rosmini, Marcelo R.

2012-01-01

The purpose of this study was to evaluate the capacity of a lactic acid bacteria (LAB) inoculum to protect calves with or without lactose supplements against Salmonella Dublin infection by evaluating histopathological lesions and pathogen translocation. Fifteen calves were divided into three groups [control group (C-G), a group inoculated with LAB (LAB-G), and a group inoculated with LAB and given lactose supplements (L-LAB-G)] with five, six, and four animals, respectively. The inoculum, composed of Lactobacillus (L.) casei DSPV 318T, L. salivarius DSPV 315T, and Pediococcus acidilactici DSPV 006T, was administered with milk replacer. The LAB-G and L-LAB-G received a daily dose of 109 CFU/kg body weight of each strain throughout the experiment. Lactose was provided to the L-LAB-G in doses of 100 g/day. Salmonella Dublin (2 × 1010 CFU) was orally administered to all animals on day 11 of the experiment. The microscopic lesion index values in target organs were 83%, 70%, and 64.3% (p < 0.05) for the C-G, LAB-G, and L-LAB-G, respectively. Administration of the probiotic inoculum was not fully effective against infection caused by Salmonella. Although probiotic treatment was unable to delay the arrival of pathogen to target organs, it was evident that the inoculum altered the response of animals against pathogen infection. PMID:23000583

The EUROCALL Review, Number 19

ERIC Educational Resources Information Center

Gimeno, Ana, Ed.

2011-01-01

"The EUROCALL Review" is published online biannually by the European Association for Computer-Assisted Language Learning (EUROCALL). This issue offers regular sections on: (1) up-to-date information on Special Interest Groups; (2) reports on on-going CALL or CALL-related R&D projects in which EUROCALL members participate; (3) reports…

The EUROCALL Review, Volume 21, Number 1

ERIC Educational Resources Information Center

Gimeno, Ana, Ed.

2013-01-01

"The EUROCALL Review" is published online biannually by the European Association for Computer-Assisted Language Learning (EUROCALL). This issue offers regular sections on: (1) up-to-date information on Special Interest Groups; (2) reports on on-going CALL or CALL-related R&D projects in which EUROCALL members participate; (3) reports…

$320,000 Kindergarten Teachers

ERIC Educational Resources Information Center

Chetty, Raj; Friedman, John N.; Hilger, Nathaniel; Saez, Emmanuel; Schanzenbach, Diane Whitmore; Yagan, Danny

2010-01-01

In Project STAR, 11,571 students in Tennessee and their teachers were randomly assigned to different classrooms in their schools from kindergarten to 3rd grade. Researchers learned that kindergarten test scores are highly correlated with such outcomes as earnings at age 27, college attendance, home ownership, and retirement savings. Students who…

Mathematics in Early Years Education. 3rd Edition

ERIC Educational Resources Information Center

Montague-Smith, Ann; Price, Alison

2012-01-01

This third edition of the best-selling "Mathematics in Nursery Education" provides an accessible introduction to the teaching of mathematics in the early years. Covering all areas of mathematics learning--number and counting, calculation, pattern, shape, measures and data handling--it summarises the research findings and underlying key concepts…

An Examination of Principals' Leadership and Its Impact on Early Elementary Grades

ERIC Educational Resources Information Center

Hallissey, Megan

2017-01-01

This exploratory, qualitative multiple-site case study examined principals' expectations of teaching practices and children's learning for early elementary grade levels (K, 1st, 2nd, and 3rd). Specifically, this study investigated principals' understanding of developmentally appropriate practices regarding instructional methods, curriculum…

The EUROCALL Review, Volume 20, Number 2

ERIC Educational Resources Information Center

Gimeno, Ana, Ed.

2012-01-01

"The EUROCALL Review" is published online biannually by the European Association for Computer-Assisted Language Learning (EUROCALL). This issue offers regular sections on: (1) up-to-date information on Special Interest Groups; (2) reports on on-going CALL or CALL-related R&D projects in which EUROCALL members participate; (3) reports…

The EUROCALL Review, Number 18

ERIC Educational Resources Information Center

Gimeno, Ana, Ed.

2011-01-01

"The EUROCALL Review" is published online biannually by the European Association for Computer-Assisted Language Learning (EUROCALL). This issue offers regular sections on: (1) up-to-date information on Special Interest Groups; (2) reports on on-going CALL or CALL-related R&D projects in which EUROCALL members participate; (3) reports…

On Safari: Animals and Their Habitats. Grades 2/3. Tapestries for Learning Series.

ERIC Educational Resources Information Center

McDonald, Heather

This thematic unit involves 2nd and 3rd grade students in an in-depth study of wild animals and their habitats. The interdisciplinary unit connects knowledge related to art, language arts, applied mathematics, social studies, and science. Students think about different types of animals from around the world and consider how they are alike and…

Non-Traditional and Interdisciplinary Programs. Selected Papers from the Annual Conference on Non-Traditional and Interdisciplinary Programs (3rd, Arlington, Virginia, July 1-3, 1985).

ERIC Educational Resources Information Center

Fonseca, James W., Comp.

Sixty-one papers are presented from the George Mason University (Virginia) annual conference on nontraditional interdisciplinary programs. They are grouped in the following categories, with three to ten papers per category: adjunct faculty; corporate/university linkages; experiential learning; graduate non-traditional programs; interdisciplinary…

Using Photographs to Probe Students' Understanding of Physical Concepts: The Case of Newton's 3rd Law

NASA Astrophysics Data System (ADS)

Eshach, Haim

2010-08-01

The starting point of the present research is the following question: since we live in an age that makes increasing use of visual representations of all sorts, is not the visual representation a learner constructs a window into his/her understanding of what is or is not being learned? Following this direction of inquiry, the present preliminary study introduces and evaluates a novel technique for pinpointing learners’ misconceptions, namely, one that has learners create and interpret their own photographs (CIP). 27 high-school students and 26 pre-service teacher trainees were asked to assume the role of textbook designers and create a display—photograph plus attached verbal explanation—which, in their opinion, best depicted Newton’s 3rd law. Subsequent analysis of the participants’ photographs yielded the following six misconception categories: 3rd law not depicted; 3rd law depicts a sequence of events; tendency to introduce irrelevant entities in explanations; the word ‘reaction’ used colloquially; tendency to restrict the application of the third law to dynamic situations; and informal explanations in which the word “force” is absent. The findings indicate that, indeed, the CIP method can be effectively employed to elicit, detect, and investigate learners’ misconceptions. The CIP method joins the growing efforts to utilize the yet relatively untapped potential of visual tools for science education purposes.

[Gender-dependent effects of histone deacetylase inhibitor sodium valproate on early olfactory learning in 129Sv mice].

PubMed

Burenkova, O V; Aleksandrova, E A; Zaraĭskaia, I Iu

2013-02-01

In the brain, histone acetylation underlies both learning and the maintenance of long-term sustained effects of early experience which is further epigenetically inherited. However, the role of acetylation in learning previously has only been studied in adult animals: high level of learning could be dependent on high levels of histone H3 acetylation in the brain. The role of acetylation in the mechanisms of early learning has not been studied. In the present work, we were interested whether histone deacetylase inhibitor sodium valproate which increases the level of histone H3 acetylation will affect early olfactory discrimination learning in 8-day-old pups of 129Sv mice that are characterized by low efficiency of learning with imitation of maternal grooming. Multiple valproate injections from 3rd to 6th postnatal day had a gender-dependent effect: learning was selectively improved in male but not in female pups. In the female pups, learning improvement was observed after multiple injections of saline. Possible epigenetic mechanisms underlying these sex differences are discussed.

PhysDoc: A Distributed Network of Physics Institutions: Collecting, Indexing, and Searching High Quality Documents by Using Harvest; The Dublin Core Metadata Initiative: Mission, Current Activities, and Future Directions; Information Services for Higher Education: A New Competitive Space; Intellectual Property Conservancies.

ERIC Educational Resources Information Center

Severiens, Thomas; Hohlfeld, Michael; Zimmermann, Kerstin; Hilf, Eberhard R.; von Ossietzky, Carl; Weibel, Stuart L.; Koch, Traugott; Hughes, Carol Ann; Bearman, David

2000-01-01

Includes four articles that discuss a variety to topics, including a distributed network of physics institutions documents called PhysDocs which harvests information from the local Web-servers of professional physics institutions; the Dublin Core metadata initiative; information services for higher education in a competitive environment; and…

Trends in the Evolution of the Public Web, 1998-2002; The Fedora Project: An Open-source Digital Object Repository Management System; State of the Dublin Core Metadata Initiative, April 2003; Preservation Metadata; How Many People Search the ERIC Database Each Day?

ERIC Educational Resources Information Center

O'Neill, Edward T.; Lavoie, Brian F.; Bennett, Rick; Staples, Thornton; Wayland, Ross; Payette, Sandra; Dekkers, Makx; Weibel, Stuart; Searle, Sam; Thompson, Dave; Rudner, Lawrence M.

2003-01-01

Includes five articles that examine key trends in the development of the public Web: size and growth, internationalization, and metadata usage; Flexible Extensible Digital Object and Repository Architecture (Fedora) for use in digital libraries; developments in the Dublin Core Metadata Initiative (DCMI); the National Library of New Zealand Te Puna…

Keeping Dublin Core Simple: Cross-Domain Discovery or Resource Description?; First Steps in an Information Commerce Economy: Digital Rights Management in the Emerging E-Book Environment; Interoperability: Digital Rights Management and the Emerging EBook Environment; Searching the Deep Web: Direct Query Engine Applications at the Department of Energy.

ERIC Educational Resources Information Center

Lagoze, Carl; Neylon, Eamonn; Mooney, Stephen; Warnick, Walter L.; Scott, R. L.; Spence, Karen J.; Johnson, Lorrie A.; Allen, Valerie S.; Lederman, Abe

2001-01-01

Includes four articles that discuss Dublin Core metadata, digital rights management and electronic books, including interoperability; and directed query engines, a type of search engine designed to access resources on the deep Web that is being used at the Department of Energy. (LRW)

Characterising the hydrothermal circulation patterns beneath thermal springs in the limestones of the Carboniferous Dublin Basin, Ireland: a geophysical and geochemical approach.

NASA Astrophysics Data System (ADS)

Blake, Sarah; Henry, Tiernan; Muller, Mark R.; Jones, Alan G.; Moore, John Paul; Murray, John; Campanyà, Joan; Vozár, Jan; Walsh, John; Rath, Volker

2016-04-01

A hydrogeological conceptual model of the sources, circulation pathways and temporal variations of two low-enthalpy thermal springs is derived from a multi-disciplinary approach. The springs are situated in the Carboniferous limestones of the Dublin Basin, in east-central Ireland. Kilbrook spring (Co. Kildare) has the highest recorded temperatures for any thermal spring in Ireland (maximum of 25.0 °C), and St. Gorman's Well (Co. Meath) has a complex and variable temperature profile (maximum of 21.8 °C). These temperatures are elevated with respect to average Irish groundwater temperatures (9.5 - 10.5 °C), and represent a geothermal energy potential, which is currently under evaluation. A multi-disciplinary investigation based upon audio-magnetotelluric (AMT) surveys, time-lapse temperature and chemistry measurements, and hydrochemical analysis, has been undertaken with the aims of investigating the provenance of the thermal groundwater and characterising the geological structures facilitating groundwater circulation in the bedrock. The hydrochemical analysis indicates that the thermal waters flow within the limestones of the Dublin Basin, and there is evidence that Kilbrook spring receives a contribution from deep-basinal fluids. The time-lapse temperature, electrical conductivity and water level records for St. Gorman's Well indicate a strongly non-linear response to recharge inputs to the system, suggestive of fluid flow in karst conduits. The 3-D electrical resistivity models of the subsurface revealed two types of geological structure beneath the springs; (1) Carboniferous normal faults, and (2) Cenozoic strike-slip faults. These structures are dissolutionally enhanced, particularly where they intersect. The karstification of these structures, which extend to depths of at least 500 m, has provided conduits that facilitate the operation of a relatively deep hydrothermal circulation pattern (likely estimated depths between 240 and 1,000 m) within the Dublin Basin. The results of this study support a hypothesis that the thermal maximum and simultaneous increased discharge observed each winter at both springs is the result of rapid infiltration, heating and re-circulation of meteoric waters within a structurally- and recharge-controlled hydrothermal circulation system.

A Guide for Parents and Families about What Your 3rd Grader Should Be Learning in School This Year. Don't Fail Your Children = Una Guia para los Padres y Familias Acerca de Lo Que Su Hijo de 3er Grado Debe Aprender en la Escuela Este Ano. No Le Falle a Sus Hijos.

ERIC Educational Resources Information Center

South Carolina State Dept. of Education, Columbia.

This guide, in English- and Spanish-language versions, shares with parents information about the South Carolina Curriculum Standards. The standards outline state requirements for children's learning and what students across the state should be able to do in certain subjects. The guide lists seven key reasons parents should be aware of the new…

Network Centric Warfare Case Study. U.S. V Corps and 3rd Infantry Division (Mechanized) During Operation Iraq Freedom Combat Operations (Mar-Apr 2003). Volume 1: Operations

DTIC Science & Technology

2003-11-01

Command Historian , and the personnel from the Center for Army Lessons Learned (CALL) for their assistance in gaining access to the many documents that...after the Network Centric Warfare Case Study operations. The Center for Army Lessons Learned (CALL), the V Corps Command Historian , and other... Historian , Dr. Charles Kirkpatrick, in Heidelberg, Germany, assisted in this effort. Nu- merous documents were collected, both unclassified and classified

Transition III in Alabama: A Profile of Commitment. Proceedings of the Annual Statewide Conference on Transition (3rd, Auburn, Alabama, January 1994).

ERIC Educational Resources Information Center

Browning, Philip, Ed.

This proceedings document provides the texts of 18 presentations given at a 3-day conference in 1993 which focused on policies, materials, programs, and activities being implemented in Alabama to foster the successful transition of youth with disabilities to adult life. First, four individuals with learning disabilities (Travis Moore, Kim…

Cognitive and Mathematical Profiles for Different Forms of Learning Difficulties

PubMed Central

Cirino, Paul T.; Fuchs, Lynn S.; Elias, John T.; Powell, Sarah R.; Schumacher, Robin F.

2014-01-01

The purpose of this study was to compare subgroups of students with various forms of learning difficulties (< 25th percentile) on cognitive and mathematics characteristics. Students with mathematics difficulty (MD, n = 105), reading difficulty (RD, n = 65), both (MDRD, n = 87), or neither (NoLD, n = 403) were evaluated on an array of cognitive measures (e.g., working memory and language) and on mathematics measures of foundational numerical competencies, computation, and problem solving. Results revealed expected level differences among groups in both domains: NoLD outperformed RD, and MD outperformed MDRD. Profile differences were noted among pairs of subgroups on cognitive measures. On mathematics measures, profile differences were noted between RD and other subgroups, but not between MD and MDRD subgroups. The most discriminating cognitive measures were processing speed and language; the most discriminating mathematics measures depended on the subgroups being compared. Results were further evaluated according to more severe (< 10th percentile) criteria for MD and RD, which generally affected level differences more than the profile patterns. Results have implications for understanding comorbid MD and RD and for conceptualizing core deficits in MD. PMID:23851137

The Book of My Dreams

ERIC Educational Resources Information Center

Degirmenci Gundogmus, Hatice

2018-01-01

This study offers an opportunity for learning the characteristics of elementary school students' dream books that can increase their willingness to read. In the study, for which the qualitative research method was adopted in line with this main purpose, 275 elementary school students that attended different schools at 2nd, 3rd and 4th grades were…

Curriculum Based Assessment: A Primer. 3rd Edition

ERIC Educational Resources Information Center

Hargis, Charles H.

2004-01-01

The use of curriculum based assessment (CBA) to ensure learning disabled and low achieving students adequate educational opportunity remains the focus in this direct and comprehensive third edition. The additions to this edition are in the way of providing detail and explanation in the context of current and emerging issues in educational…

Effects of a Short Strategy Training on Metacognitive Monitoring across the Life-Span

ERIC Educational Resources Information Center

von der Linden, Nicole; Löffler, Elisabeth; Schneider, Wolfgang

2015-01-01

The present study was conducted to explore the potential positive influence of a short strategy training on metacognitive monitoring competencies covering a life-span approach. Participants of four age groups (3rd-grade children, adolescents, younger and older adults) concluded a paired-associate learning task. Additionally, they gave delayed…

IT [Information Technology] in Vocational Education [and] Training. Paper Presentations: Session D.

ERIC Educational Resources Information Center

2000

This document contains 15 papers from the information technology (IT) in vocational education and training (VET) section of an international conference on VET for lifelong learning in the information era. The following papers are included: "Adapting the System of Continuing Vocational Education for the 3rd Industrial Revolution--Experiences…

Effects of notetaking instruction on 3rd grade student's science learning and notetaking behavior

NASA Astrophysics Data System (ADS)

Lee, Pai-Lin

The research examined effects of notetaking instruction on elementary-aged students' ability to recall science information and notetaking behavior. Classes of 3rd grade students were randomly assigned to three treatment conditions, strategic notetaking, partial strategic notetaking, and control, for 4 training sessions. The effects of the notetaking instruction were measured by their performances on a test on science information taught during the training, a long-term free recall of the information, and number of information units recalled with or without cues. Students' prior science achievement was used to group students into two levels (high vs. low) and functioned as another independent variable in analysis. Results indicated significant treatment effect on cued and non-cued recall of the information units in favor of the strategy instruction groups. Students with higher prior achievement in science performed better on cued recall and long-term free recall of information. The results suggest that students as young as at the third grade can be instructed to develop the ability of notetaking that promotes their learning.

Does Special Care Dentistry undergraduate teaching improve dental student attitudes towards people with disabilities?

PubMed

Mac Giolla Phadraig, C; Nunn, J H; Tornsey, O; Timms, M

2015-05-01

Undergraduate dental curricula increasingly aim to address student attitudes towards people with disabilities. This study reports the effectiveness of a comprehensive, blended learning Special Care Dentistry undergraduate programme to change attitudes towards people with disabilities. A validated psychometric instrument (ATDP-Form 0) was given as a course evaluation to third-year dental students in the Dublin Dental University Hospital over 3 years from 2010 to 2013, immediately before and after the delivery of a brief comprehensive curriculum in Special Care Dentistry. From a population of 109 students, 100 (91.7%) pre-test and 83 (76.1%) retest responses were analysed. Mean score before the course, for all years, was 74.8 (SD = 14.7), compared with 76.8 (SD = 14.0) for all years after the course. Dental students in our study had neither particularly positive, or negative attitudes towards people with disabilities. There was no statistically significant difference in student attitudes before and after the educational intervention. This study, therefore, shows that a comprehensive undergraduate blended learning module, which aimed to improve attitudes towards people with disabilities, did not do so, using the described measures within the selected timeframe. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Epidemiology of virulence-associated plasmids and outer membrane protein patterns within seven common Salmonella serotypes.

PubMed

Helmuth, R; Stephan, R; Bunge, C; Hoog, B; Steinbeck, A; Bulling, E

1985-04-01

Antibiotic-sensitive Salmonella isolates belonging to seven common serotypes and originating from 29 different countries from all continents were investigated for their plasmid DNA content (337 isolates) and their outer membrane protein profiles (216 isolates). Of the S. typhimurium, S. enteritidis, S. dublin, and S. choleraesuis isolates, 90% or more carried a serotype-specific plasmid. The molecular sizes of the plasmids were 60 megadaltons (Md) for S. typhimurium, 37 Md for S. enteritidis, 56 Md for S. dublin, and 30 Md for S. choleraesuis. The outer membrane protein profiles were homogeneous within each of the seven serotypes, except that a minority of S. enteritidis and S. dublin strains were lacking one major outer membrane protein. Virulence studies were performed with 39 representative strains by measuring the 50% lethal doses (LD50S) after oral infection of mice. The LD50 values obtained for plasmid-positive strains of S. typhimurium, S. enteritidis, and S. dublin were up to 10(6)-fold lower than the values obtained for the plasmid-free strains of the same serotype. Only the plasmid-positive strains could invade the livers of orally infected mice, and only they were resistant to the bactericidal activity of 90% guinea pig serum. Strains of S. infantis were generally plasmid free, whereas S. panama and S. heidelberg isolates carried heterogeneous plasmid populations. The virulence properties of the latter three serotypes could not be correlated with the predominant plasmids found in these strains.

Epidemiology of virulence-associated plasmids and outer membrane protein patterns within seven common Salmonella serotypes.

PubMed Central

Helmuth, R; Stephan, R; Bunge, C; Hoog, B; Steinbeck, A; Bulling, E

1985-01-01

Antibiotic-sensitive Salmonella isolates belonging to seven common serotypes and originating from 29 different countries from all continents were investigated for their plasmid DNA content (337 isolates) and their outer membrane protein profiles (216 isolates). Of the S. typhimurium, S. enteritidis, S. dublin, and S. choleraesuis isolates, 90% or more carried a serotype-specific plasmid. The molecular sizes of the plasmids were 60 megadaltons (Md) for S. typhimurium, 37 Md for S. enteritidis, 56 Md for S. dublin, and 30 Md for S. choleraesuis. The outer membrane protein profiles were homogeneous within each of the seven serotypes, except that a minority of S. enteritidis and S. dublin strains were lacking one major outer membrane protein. Virulence studies were performed with 39 representative strains by measuring the 50% lethal doses (LD50S) after oral infection of mice. The LD50 values obtained for plasmid-positive strains of S. typhimurium, S. enteritidis, and S. dublin were up to 10(6)-fold lower than the values obtained for the plasmid-free strains of the same serotype. Only the plasmid-positive strains could invade the livers of orally infected mice, and only they were resistant to the bactericidal activity of 90% guinea pig serum. Strains of S. infantis were generally plasmid free, whereas S. panama and S. heidelberg isolates carried heterogeneous plasmid populations. The virulence properties of the latter three serotypes could not be correlated with the predominant plasmids found in these strains. Images PMID:3980081

An inventory of trees in Dublin city centre.

PubMed

Ningal, Tine; Mills, Gerald; Smithwick, Pamela

2010-01-01

While urban areas are often considered to be comprised chiefly of artificial surfaces, they can contain a substantial portion of green space and a great diversity of natural habitats. These spaces include public parks, private gardens and street trees, all of which can provide valuable environmental services, such as improved air quality. Trees play a particular role in cities as they are often placed along roadsides and in the median strip of busy streets. As such they regulate access to sunshine, restrict airflow, provide shelter, scavenge air pollutants and manage noise at the street level. A tree planting policy can be an important part of a broader environmental strategy aimed at improving the quality of life in urban areas but this requires up-to-date knowledge of the current tree stock, which does not exist for Dublin. This article presents an inventory of trees in Dublin's city centre, defined as the area between the Grand and Royal canals. The results show that there are over 10,000 trees in the study area representing a density of 684 trees km-2 or one tree to approximately every 50 residents of the city centre. The tree canopy extent when in full foliage was nearly 1 km2 in extent or 6% of the study area. A more detailed analysis of those trees planted along streets shows little species variation but clear distinction in the sizes of trees, which is indicative of the age of planting. These data are used to estimate the carbon stored in Dublin's trees.

Use of social information in the problem solving of orangutans (Pongo pygmaeus) and human children (Homo sapiens).

PubMed

Call, J; Tomasello, M

1995-09-01

Fourteen juvenile and adult orangutans and 24 3- and 4-year-old children participated in 4 studies on imitative learning in a problem-solving situation. In all studies a simple to operate apparatus was used, but its internal mechanism was hidden from subjects to prevent individual learning. In the 1st study, orangutans observed a human demonstrator perform 1 of 4 actions on the apparatus and obtain a reward; they subsequently showed no signs of imitative learning. Similar results were obtained in a 2nd study in which orangutan demonstrators were used. Similar results were also obtained in a 3rd study in which a human encouraged imitation from an orangutan that had previously been taught to mimic arbitrary human actions. In a 4th study, human 3- and 4-year-old children learned the task by means of imitation.

Peer Tutoring and Clinical Stage: analysis of experience and potential applications in the First Level Degree Course in Nursing, section of Desenzano Del Garda.

PubMed

Lo Biondo, Paolo; Avino, Nicola; Podavini, Enrica; Prandelli, Matteo

2015-01-01

Among the various methods of learning and experience in the literature, the methodology of Peer Tutoring is particularly important for the formation of the student nurses. The Peer Tutoring identifies a model of cooperative learning, aiming to activate a spontaneous process to transfer knowledge, emotions and experiences from some members of a group to other members of equal status but with a difference in the knowledge and cognitive skills or relational. The First level degree course in Nursing, section of Desenzano del Garda (Brescia, Italy) has been applying a methodology that can be defined as Peer Tutoring for the last four years. The applicability of the method is based on the coupling of an expert student of the 3rd year of the course to a group of students from the 1st or 2nd year. The study has the main objective to analyze the experience in the branch of Desenzano del Garda and see if the learning method of the Peer Tutoring is valid within the context of clinical internship. The study, of descriptive-observational type, was conducted in the academic year 2013-2014. The samples in the research are two: the first sample consisted of 53 students in their first year of studies, 46 students of the 2nd year of the course and 30 students of the 3rd year of the course who attended the experience as tutoring students (students tutors), for a total of 129 students; the second sample consisted of 15 students of the 3rd year of the course who attended the experience of the Peer Tutoring applied to the Stage clinical students as tutors (students Tutor). The research allowed important information to be gathered regarding the utility and interventions to improve the quality of the project of Peer tutoring. Peer Tutoring is a learning methodology that works and that can be applied in learning pathways for nursing students. The training of students Tutor is a matter of considerable importance: in fact the students ask to be trained to respect the structure and functions of the organizations in which they are inserted, in the management of the groups, the educational skills and techniques and teaching strategies.

Physical exercise improves learning in zebrafish, Danio rerio.

PubMed

Luchiari, Ana Carolina; Chacon, Diana Marques Martins

2013-11-01

Zebrafish is an ideal vertebrate model for neuroscience studies focusing on learning and memory. Although genetic manipulation of zebrafish is available, behavioral protocols are often lacking. In this study we tested whether physical activity can facilitate zebrafish's learning process in an associative conditioning task. Learning was inferred by the approach of the feeding area just after the conditioned stimulus (light). Unexercised zebrafish showed conditioning response from the 5th testing day while fish previously submitted to swim against the water current showed learning by the 3rd day of testing. It seems that physical activity may accelerate associative learning response in zebrafish, indicating the benefits of exercise for cognitive processes. We suggest that this preliminary work could be useful for high throughput screening. Copyright © 2013 Elsevier B.V. All rights reserved.

Mathematical learning disorder in school-age children with attention-deficit hyperactivity disorder.

PubMed

Capano, Lucia; Minden, Debbie; Chen, Shirley X; Schacher, Russell J; Ickowicz, Abel

2008-06-01

To explore the prevalence of mathematics disorder (MD) relative to reading disorders (RD) in school-age children with attention-deficit hyperactivity disorder (ADHD) and examine the effects of age, sex, cooccurring conduct disorder (CD), and ADHD subtype on this comorbidity. Participants were school-age children (n = 476) with confirmed DSM-IV diagnosis of ADHD. The assessment included semistructured parent and teacher interviews and standardized measures of intelligence, academic attainment, and language abilities. Based on the presence or absence of concurrent learning disorders, we compared the emerging 4 groups: ADHD-only, ADHD + MD, ADHD + RD, and ADHD + MD + RD. Overall prevalence of comorbid ADHD + MD was 18.1%. Age, sex, ADHD subtypes, or comorbid CD did not affect the frequency of MD. Children with concurrent ADHD and either MD or RD attained lower IQ, language, and academic scores than those with ADHD alone. Children with ADHD + MD + RD were more seriously impaired and demonstrated distinct deficits in receptive and expressive language. MDs are relatively common in school-age children with ADHD and are frequently associated with RDs. Children with ADHD + MD + RD are more severely impaired. These deficits simply cannot be explained as consequences of ADHD and might have unique biological underpinnings, with implications for diagnostic classification and therapeutic interventions.

Texarkana Battles Dropout Dilemma

ERIC Educational Resources Information Center

Filogamo, Martin J.

1970-01-01

Describes multimedia learning centers, established with government funding, for which the contractor, Dorsett Educational Systems, will be paid according to the increased learning efficiency of participating students. (RD)

Problem-based learning in comparison with lecture-based learning among medical students.

PubMed

Faisal, Rizwan; Bahadur, Sher; Shinwari, Laiyla

2016-06-01

To compare performance of medical students exposed to problem-based learning and lecture-based learning. The descriptive study was conducted at Rehman Medical College, Peshawar, Pakistan from May 20 to September 20, 2014, and comprised 146 students of 3rd year MBBS who were randomised into two equal groups. One group was taught by the traditional lecture based learning, while problem-based learning was conducted for the other group on the same topic. At the end of sessions, the performance of the two groups was evaluated by one-best type of 50 multiple choice questions. Total marks were 100, with each question carrying 2 marks. SPSS 15 was used for statistical analysis. There were 146 students who were divided into two equal groups of 73(50%) each. The mean score in the group exposed to problem-based learning was 3.2 ± 0.8 while those attending lecture-based learning was 2.7±0.8 (p= 0.0001). Problem-based learning was more effective than lecture based learning in the academic performance of medical students.

Unsupervised deep learning reveals prognostically relevant subtypes of glioblastoma.

PubMed

Young, Jonathan D; Cai, Chunhui; Lu, Xinghua

2017-10-03

One approach to improving the personalized treatment of cancer is to understand the cellular signaling transduction pathways that cause cancer at the level of the individual patient. In this study, we used unsupervised deep learning to learn the hierarchical structure within cancer gene expression data. Deep learning is a group of machine learning algorithms that use multiple layers of hidden units to capture hierarchically related, alternative representations of the input data. We hypothesize that this hierarchical structure learned by deep learning will be related to the cellular signaling system. Robust deep learning model selection identified a network architecture that is biologically plausible. Our model selection results indicated that the 1st hidden layer of our deep learning model should contain about 1300 hidden units to most effectively capture the covariance structure of the input data. This agrees with the estimated number of human transcription factors, which is approximately 1400. This result lends support to our hypothesis that the 1st hidden layer of a deep learning model trained on gene expression data may represent signals related to transcription factor activation. Using the 3rd hidden layer representation of each tumor as learned by our unsupervised deep learning model, we performed consensus clustering on all tumor samples-leading to the discovery of clusters of glioblastoma multiforme with differential survival. One of these clusters contained all of the glioblastoma samples with G-CIMP, a known methylation phenotype driven by the IDH1 mutation and associated with favorable prognosis, suggesting that the hidden units in the 3rd hidden layer representations captured a methylation signal without explicitly using methylation data as input. We also found differentially expressed genes and well-known mutations (NF1, IDH1, EGFR) that were uniquely correlated with each of these clusters. Exploring these unique genes and mutations will allow us to further investigate the disease mechanisms underlying each of these clusters. In summary, we show that a deep learning model can be trained to represent biologically and clinically meaningful abstractions of cancer gene expression data. Understanding what additional relationships these hidden layer abstractions have with the cancer cellular signaling system could have a significant impact on the understanding and treatment of cancer.

[The importance of early diagnosis and intervention in children diagnosed with reading disorder. Case studies].

PubMed

Törö, Krisztina; Balázs, Judit

2015-06-01

Reading Disorder (RD) belongs to Specific Learning Disorders within the chapter of Neurodevelopmental Disorders in the Diagnostic and Statistic Manual of Mental Disorders 5th edition. Previous research shows that the time of the diagnosis of RD - early (before starting school) or late - has a great impact on the prognosis. In the current paper we present the cases of two children diagnosed with RD. Our cases demonstrate that if RD is diagnosed in early childhood, the child's and his/her family's quality of life can be influenced in a positive direction, while late recognition of RD might influence the child's and the family's quality of life negatively. For these reasons it is important that experts recognize RD in time, start appropriate treatment and give proper support to children diagnosed with RD and their families.

Male street prostitution in Dublin: a psychological analysis.

PubMed

McCabe, Ian; Acree, Michael; O'Mahony, Finbar; McCabe, Jenny; Kenny, Jean; Twyford, Jennifer; Quigley, Karen; McGlanaghy, Edel

2011-01-01

This study assessed the mental health characteristics of 12 male street prostitutes (MSPs) in Dublin, with particular regard to issues of homelessness, substance abuse, depression, suicidal ideation, and self-esteem. Participants completed five psychometric tests, which indicated that all of the participants had above average levels of depression and suicidal ideation and low levels of self-esteem. This study found that candidates likely to become MSPs are young males with a combination of factors, including a background of childhood sexual or physical abuse, leaving school early, running away from home, and a dependence on heroin.

Jonathan Osborne (1794-1864) MD FRCPI: a crypto-neurologist.

PubMed

Breathnach, Caoimhghín S

2009-08-01

Jonathan Osborne was born in Dublin and educated in Trinity College Dublin, where he became Professor of Materia Medica. As physician to Sir Patrick Dun's and Mercer Hospitals he reported extensively on those patients who came under his care. In his native city he is remembered for the instruments he devised, for his studies on dropsies (particularly albuminuric nephritis), and for his therapeutic approach to epilepsy and neuralgia. It is his thorough analysis of a patient with conduction aphasia in 1833, however, which has stood the test of time.

Supporting 3rd-Grade Students Model-Based Explanations about Groundwater: A Quasi-Experimental Study of a Curricular Intervention

ERIC Educational Resources Information Center

Zangori, Laura; Vo, Tina; Forbes, Cory T.; Schwarz, Christina V.

2017-01-01

Scientific modelling is a key practice in which K-12 students should engage to begin developing robust conceptual understanding of natural systems, including water. However, little past research has explored primary students' learning about groundwater, engagement in scientific modelling, and/or the ways in which teachers conceptualise and…

Pedestrian Safety: Injury Control Curriculum Guide (For K - 3rd Grade). Second Edition.

ERIC Educational Resources Information Center

Wooner, Rosestelle B., Ed.

This curriculum guide attempts to help the early childhood teacher show children how to incorporate safety precautions into daily life. Good safety practices can prevent the death or injury of young children by automobile, truck, bus, pedestrian, bicycle, and tricycle accidents. The guide focuses on student involvement in the learning process and…

Comparative-Descriptive Study of Academic Vocabulary Specific Instruction on 3rd Grade English Language Learner Reading Scores

ERIC Educational Resources Information Center

Ward, Shelley

2017-01-01

Language must be taught with academic vocabulary that is meaningful and that can be transferred between content and context. This comparative-descriptive research study examines how academic specific instruction increases students' learning of a second language acquisition (i.e., English). The conceptual framework of the study drew research…

Use of Lecture Capture in Undergraduate Biological Science Education

ERIC Educational Resources Information Center

Wiese, Candace; Newton, Genevieve

2013-01-01

This study examined the use of lecture capture in students in a large 3rd year undergraduate biological science course at the University of Guelph. Data regarding viewing behaviour, academic performance, and attendance were analyzed in relation to student learning approach (as assessed by the R-SPQ-2F), gender, and year of post-secondary…

Empirical Validation of Integrated Learning Performances for Hydrologic Phenomena: 3rd-Grade Students' Model-Driven Explanation-Construction

ERIC Educational Resources Information Center

Forbes, Cory T.; Zangori, Laura; Schwarz, Christina V.

2015-01-01

Water is a crucial topic that spans the K-12 science curriculum, including the elementary grades. Students should engage in the articulation, negotiation, and revision of model-based explanations about hydrologic phenomena. However, past research has shown that students, particularly early learners, often struggle to understand hydrologic…

Effective Partnerships in School Reform: Lessons Learned from the Midwest Child-Parent Center Expansion

ERIC Educational Resources Information Center

Hayakawa, Momoko; Englund, Michelle M.; Candee, Allyson; Lease, Erin; Sullivan, Molly; Warner-Richter, Mallory; Reynolds, Arthur J.

2015-01-01

The Midwest Expansion of the Child-Parent Center Education Program (MCPC) is a pre-K to 3rd grade intervention program aimed at improving economically disadvantaged children's school success by enhancing continuity in instruction and increasing parental involvement. Opened in Chicago in the 1960s, this school reform model has undergone significant…

Teaching Visually Impaired Children. 3rd Edition

ERIC Educational Resources Information Center

Bishop, Virginia E.

2004-01-01

In this exceptional new third edition, the author has retained much of the practical "how to" approach of the previous editions, but adds depth in two dimensions: learning theory and the educational process. This book is "so comprehensive in scope and complete in detail that it would be the most likely recommended" (from the foreword by Dr.…

Boyz to Men? Teaching to Restore Black Boys' Childhood

ERIC Educational Resources Information Center

Ladson Billings, Gloria

2011-01-01

Many schools see teaching African American boys as a daunting challenge. However, in many schools the primary focus of Black male children's educational experience is maintaining order and discipline rather than student learning and academic achievement. By the time Black boys reach the 3rd or 4th grade their teachers and other school personnel no…

The Young Artist as Scientist: What Can Leonardo Teach Us?

ERIC Educational Resources Information Center

Pollman, Mary Jo

2017-01-01

This is the first in-depth look at the important connections between the arts and science specifically for early childhood education (pre-K-3rd grade). Highlighting their many commonalities, such as the processes involved in creative problem solving, the author draws on what we can learn from Leonardo da Vinci as the supreme artist-scientist.…

Preliminary Impacts of SECURe PreK on Child- and Classroom-Level Outcomes

ERIC Educational Resources Information Center

Jones, Stephanie M.; Kargman, Marie; Kargman, Max; Bailey, Rebecca

2014-01-01

This paper presents initial results from a pilot evaluation of the pre-K component of a new school-based intervention strategy (Social, Emotional, and Cognitive Understanding and Regulation in education, SECURe) for pre-kindergarten through 3rd grade that is designed to build skills in social-emotional learning (focusing on executive function and…

The Electric Company; Television and Reading, 1971-1980: A Mid-Experiment Appraisal.

ERIC Educational Resources Information Center

Cooney, Joan Ganz

"The Electric Company" was created by the Children's Television Workshop as an experiment to teach reading to 2nd, 3rd, and 4th grade children having difficulty learning to read. Solidly based on research in the teaching of reading, the curriculum emphasizes decoding skills. The production process included several phases: (1) assembling…

The International Cytokine Conference (11th) Held in Dublin (Ireland) on September 20-24 2003 (European Cytokine Network, Volume 14, Number 3, September 2003)

DTIC Science & Technology

2003-09-01

Fisiologia Celular UNAM, Mexico City/ Mexico specific marker of bacterial sepsis. Despite the increasing clinical importance of PCT the knowledge about its...about their function or scription factor NF-kappaB. Likewise, Varicella -zoster virus strongly mechanism of action. activates the AP- 1 components Jun and

Toy talk: simple strategies to create richer grammatical input.

PubMed

Hadley, Pamela A; Walsh, Kathleen M

2014-07-01

The purpose of this initial feasibility study was to determine whether brief instruction in toy talk would change grammatical properties of adult language, specifically 3rd person lexical noun phrase (NP) subjects. Eighteen college students participated in the study. The use of 3rd person subjects was examined before and after instruction on toy talk strategies (i.e., talk about the toys, give the item its name). Change in the input informativeness for tense (i.e., the proportion of verb forms marked for tense out of all verb forms) was also examined, although adults were not instructed on use of tense/agreement morphemes. Following instruction, statistically significant increases with large effect sizes were observed for use of 3rd person subjects, lexical NP subjects, and input informativeness for tense (Cohen's d = 1.20, 2.08, and 0.89, respectively). These findings demonstrate that young adults can learn these simple strategies with relatively brief instruction, and the use of toy talk also changes the richness of tense/agreement marking in adult language input. Considerations for incorporating toy talk into existing language modeling practices and future plans for evaluating the efficacy of toy talk are discussed.

Hyper Text Mark-up Language and Dublin Core metadata element set usage in websites of Iranian State Universities' libraries.

PubMed

Zare-Farashbandi, Firoozeh; Ramezan-Shirazi, Mahtab; Ashrafi-Rizi, Hasan; Nouri, Rasool

2014-01-01

Recent progress in providing innovative solutions in the organization of electronic resources and research in this area shows a global trend in the use of new strategies such as metadata to facilitate description, place for, organization and retrieval of resources in the web environment. In this context, library metadata standards have a special place; therefore, the purpose of the present study has been a comparative study on the Central Libraries' Websites of Iran State Universities for Hyper Text Mark-up Language (HTML) and Dublin Core metadata elements usage in 2011. The method of this study is applied-descriptive and data collection tool is the check lists created by the researchers. Statistical community includes 98 websites of the Iranian State Universities of the Ministry of Health and Medical Education and Ministry of Science, Research and Technology and method of sampling is the census. Information was collected through observation and direct visits to websites and data analysis was prepared by Microsoft Excel software, 2011. The results of this study indicate that none of the websites use Dublin Core (DC) metadata and that only a few of them have used overlaps elements between HTML meta tags and Dublin Core (DC) elements. The percentage of overlaps of DC elements centralization in the Ministry of Health were 56% for both description and keywords and, in the Ministry of Science, were 45% for the keywords and 39% for the description. But, HTML meta tags have moderate presence in both Ministries, as the most-used elements were keywords and description (56%) and the least-used elements were date and formatter (0%). It was observed that the Ministry of Health and Ministry of Science follows the same path for using Dublin Core standard on their websites in the future. Because Central Library Websites are an example of scientific web pages, special attention in designing them can help the researchers to achieve faster and more accurate information resources. Therefore, the influence of librarians' ideas on the awareness of web designers and developers will be important for using metadata elements as general, and specifically for applying such standards.

Hyper Text Mark-up Language and Dublin Core metadata element set usage in websites of Iranian State Universities’ libraries

PubMed Central

Zare-Farashbandi, Firoozeh; Ramezan-Shirazi, Mahtab; Ashrafi-Rizi, Hasan; Nouri, Rasool

2014-01-01

Introduction: Recent progress in providing innovative solutions in the organization of electronic resources and research in this area shows a global trend in the use of new strategies such as metadata to facilitate description, place for, organization and retrieval of resources in the web environment. In this context, library metadata standards have a special place; therefore, the purpose of the present study has been a comparative study on the Central Libraries’ Websites of Iran State Universities for Hyper Text Mark-up Language (HTML) and Dublin Core metadata elements usage in 2011. Materials and Methods: The method of this study is applied-descriptive and data collection tool is the check lists created by the researchers. Statistical community includes 98 websites of the Iranian State Universities of the Ministry of Health and Medical Education and Ministry of Science, Research and Technology and method of sampling is the census. Information was collected through observation and direct visits to websites and data analysis was prepared by Microsoft Excel software, 2011. Results: The results of this study indicate that none of the websites use Dublin Core (DC) metadata and that only a few of them have used overlaps elements between HTML meta tags and Dublin Core (DC) elements. The percentage of overlaps of DC elements centralization in the Ministry of Health were 56% for both description and keywords and, in the Ministry of Science, were 45% for the keywords and 39% for the description. But, HTML meta tags have moderate presence in both Ministries, as the most-used elements were keywords and description (56%) and the least-used elements were date and formatter (0%). Conclusion: It was observed that the Ministry of Health and Ministry of Science follows the same path for using Dublin Core standard on their websites in the future. Because Central Library Websites are an example of scientific web pages, special attention in designing them can help the researchers to achieve faster and more accurate information resources. Therefore, the influence of librarians’ ideas on the awareness of web designers and developers will be important for using metadata elements as general, and specifically for applying such standards. PMID:24741646

Automatic extraction of road features in urban environments using dense ALS data

NASA Astrophysics Data System (ADS)

Soilán, Mario; Truong-Hong, Linh; Riveiro, Belén; Laefer, Debra

2018-02-01

This paper describes a methodology that automatically extracts semantic information from urban ALS data for urban parameterization and road network definition. First, building façades are segmented from the ground surface by combining knowledge-based information with both voxel and raster data. Next, heuristic rules and unsupervised learning are applied to the ground surface data to distinguish sidewalk and pavement points as a means for curb detection. Then radiometric information was employed for road marking extraction. Using high-density ALS data from Dublin, Ireland, this fully automatic workflow was able to generate a F-score close to 95% for pavement and sidewalk identification with a resolution of 20 cm and better than 80% for road marking detection.

Cognitive and mathematical profiles for different forms of learning difficulties.

PubMed

Cirino, Paul T; Fuchs, Lynn S; Elias, John T; Powell, Sarah R; Schumacher, Robin F

2015-01-01

The purpose of this study was to compare subgroups of students with various forms of learning difficulties (< 25th percentile) on cognitive and mathematics characteristics. Students with mathematics difficulty (MD, n = 105), reading difficulty (RD, n = 65), both (MDRD, n = 87), or neither (NoLD, n = 403) were evaluated on an array of cognitive measures (e.g., working memory and language) and on mathematics measures of foundational numerical competencies, computation, and problem solving. Results revealed expected level differences among groups in both domains: NoLD outperformed RD, and MD outperformed MDRD. Profile differences were noted among pairs of subgroups on cognitive measures. On mathematics measures, profile differences were noted between RD and other subgroups, but not between MD and MDRD subgroups. The most discriminating cognitive measures were processing speed and language; the most discriminating mathematics measures depended on the subgroups being compared. Results were further evaluated according to more severe (< 10th percentile) criteria for MD and RD, which generally affected level differences more than the profile patterns. Results have implications for understanding comorbid MD and RD and for conceptualizing core deficits in MD. © Hammill Institute on Disabilities 2013.

Smoking characteristics of Polish immigrants in Dublin

PubMed Central

Kabir, Zubair; Clarke, Vanessa; Keogan, Sheila; Currie, Laura M; Zatonski, Witold; Clancy, Luke

2008-01-01

Background This study examined two main hypotheses: a) Polish immigrants' smoking estimates are greater than their Irish counterparts (b) Polish immigrants purchasing cigarettes from Poland smoke "heavier" (≥ 20 cigarettes a day) when compared to those purchasing cigarettes from Ireland. The study also set out to identify significant predictors of 'current' smoking (some days and everyday) among the Polish immigrants. Methods Dublin residents of Polish origin (n = 1,545) completed a previously validated Polish questionnaire in response to an advertisement in a local Polish lifestyle magazine over 5 weekends (July–August, 2007). The Office of Tobacco Control telephone-based monthly survey data were analyzed for the Irish population in Dublin for the same period (n = 484). Results Age-sex adjusted smoking estimates were: 47.6% (95% Confidence Interval [CI]: 47.3%; 48.0%) among the Poles and 27.8% (95% CI: 27.2%; 28.4%) among the general Irish population (p < 0.001). Of the57% of smokers (n = 345/606) who purchased cigarettes solely from Poland and the 33% (n = 198/606) who purchased only from Ireland, 42.6% (n = 147/345) and 41.4% (n = 82/198) were "heavy" smokers, respectively (p = 0.79). Employment (Odds Ratio [OR]: 2.89; 95% CI: 1.25–6.69), lower education (OR: 3.76; 95%CI: 2.46–5.74), and a longer stay in Ireland (>24 months) were significant predictors of current smoking among the Poles. An objective validation of the self-reported smoking history of a randomly selected sub-sample immigrant group, using expired carbon monoxide (CO) measurements, showed a highly significant correlation coefficient (r = 0.64) of expired CO levels with the reported number of cigarettes consumed (p < 0.0001). Conclusion Polish immigrants' smoking estimates are higher than their Irish counterparts, and particularly if employed, with only primary-level education, and are overseas >2 years. PMID:19117510

Tensor Decompositions for Learning Latent Variable Models

DTIC Science & Technology

2012-12-08

and eigenvectors of tensors is generally significantly more complicated than their matrix counterpart (both algebraically [Qi05, CS11, Lim05] and...The reduction First, let W ∈ Rd×k be a linear transformation such that M2(W,W ) = W M2W = I where I is the k × k identity matrix (i.e., W whitens ...approximate the whitening matrix W ∈ Rd×k from second-moment matrix M2 ∈ Rd×d. To do this, one first multiplies M2 by a random matrix R ∈ Rd×k′ for some k′ ≥ k

Detection of Salmonella spp. in veterinary samples by combining selective enrichment and real-time PCR.

PubMed

Goodman, Laura B; McDonough, Patrick L; Anderson, Renee R; Franklin-Guild, Rebecca J; Ryan, James R; Perkins, Gillian A; Thachil, Anil J; Glaser, Amy L; Thompson, Belinda S

2017-11-01

Rapid screening for enteric bacterial pathogens in clinical environments is essential for biosecurity. Salmonella found in veterinary hospitals, particularly Salmonella enterica serovar Dublin, can pose unique challenges for culture and testing because of its poor growth. Multiple Salmonella serovars including Dublin are emerging threats to public health given increasing prevalence and antimicrobial resistance. We adapted an automated food testing method to veterinary samples and evaluated the performance of the method in a variety of matrices including environmental samples ( n = 81), tissues ( n = 52), feces ( n = 148), and feed ( n = 29). A commercial kit was chosen as the basis for this approach in view of extensive performance characterizations published by multiple independent organizations. A workflow was established for efficiently and accurately testing veterinary matrices and environmental samples by use of real-time PCR after selective enrichment in Rappaport-Vassiliadis soya (RVS) medium. Using this method, the detection limit for S. Dublin improved by 100-fold over subculture on selective agars (eosin-methylene blue, brilliant green, and xylose-lysine-deoxycholate). Overall, the procedure was effective in detecting Salmonella spp. and provided next-day results.

The Brady Bunch? New evidence for nominative determinism in patients' health: retrospective, population based cohort study.

PubMed

Keaney, John J; Groarke, John D; Galvin, Zita; McGorrian, Catherine; McCann, Hugh A; Sugrue, Declan; Keelan, Edward; Galvin, Joseph; Blake, Gavin; Mahon, Niall G; O'Neill, James

2013-12-12

To ascertain whether a name can influence a person's health, by assessing whether people with the surname "Brady" have an increased prevalence of bradycardia. Retrospective, population based cohort study. One university teaching hospital in Dublin, Ireland. People with the surname "Brady" in Dublin, determined through use of an online telephone directory. Prevalence of participants who had pacemakers inserted for bradycardia between 1 January 2007 and 28 February 2013. 579 (0.36%) of 161,967 people who were listed on the Dublin telephone listings had the surname "Brady." The proportion of pacemaker recipients was significantly higher among Bradys (n=8, 1.38%) than among non-Bradys (n=991, 0.61%; P=0.03). The unadjusted odds ratio (95% confidence interval) for pacemaker implantation among individuals with the surname Brady compared with individuals with other surnames was 2.27 (1.13 to 4.57). Patients named Brady are at increased risk of needing pacemaker implantation compared with the general population. This finding shows a potential role for nominative determinism in health.

Tom O'Connor: His legacy of atmospheric aerosol research in Ireland

NASA Astrophysics Data System (ADS)

Jennings, S. Gerard

2013-05-01

Dr. Thomas C. (Tom) O'Connor received his foundation in atmospheric aerosols through his M. Sc. work at University College Dublin (with P.J. Nolan) and then as research scholar with Leo W. Pollak at the Dublin Institute of Advanced Studies. On moving to Galway in 1956, a significant legacy was his choosing of a field station site at Mace Head and his pioneering measurements there. He played a pivotal role in the development and progression of the Mace Head Atmospheric Research Station (www.macehead.org) for some 50 years. He passed away peacefully in November 2012.

[Primary Study on Predicting the Termination of Paroxysmal Atrial Fibrillation Based on a Novel RdR RR Intervals Scatter Plot].

PubMed

Lu, Hongwei; Zhang, Chenxi; Sun, Ying; Hao, Zhidong; Wang, Chunfang; Tian, Jiajia

2015-08-01

Predicting the termination of paroxysmal atrial fibrillation (AF) may provide a signal to decide whether there is a need to intervene the AF timely. We proposed a novel RdR RR intervals scatter plot in our study. The abscissa of the RdR scatter plot was set to RR intervals and the ordinate was set as the difference between successive RR intervals. The RdR scatter plot includes information of RR intervals and difference between successive RR intervals, which captures more heart rate variability (HRV) information. By RdR scatter plot analysis of one minute RR intervals for 50 segments with non-terminating AF and immediately terminating AF, it was found that the points in RdR scatter plot of non-terminating AF were more decentralized than the ones of immediately terminating AF. By dividing the RdR scatter plot into uniform grids and counting the number of non-empty grids, non-terminating AF and immediately terminating AF segments were differentiated. By utilizing 49 RR intervals, for 20 segments of learning set, 17 segments were correctly detected, and for 30 segments of test set, 20 segments were detected. While utilizing 66 RR intervals, for 18 segments of learning set, 16 segments were correctly detected, and for 28 segments of test set, 20 segments were detected. The results demonstrated that during the last one minute before the termination of paroxysmal AF, the variance of the RR intervals and the difference of the neighboring two RR intervals became smaller. The termination of paroxysmal AF could be successfully predicted by utilizing the RdR scatter plot, while the predicting accuracy should be further improved.

Can Executive Functions Help to Understand Children with Mathematical Learning Disorders and to Improve Instruction?

ERIC Educational Resources Information Center

Desoete, Annemie; De Weerdt, Frauke

2013-01-01

Working memory, inhibition and naming speed was assessed in 22 children with mathematical learning disorders (MD), 17 children with a reading learning disorder (RD), and 45 children without any learning problems between 8 and 12 years old. All subjects with learning disorders performed poorly on working memory tasks, providing evidence that they…

The benefits of utilising geo-mapping for visualising the vitamin D status of Dublin city and the surrounding urban districts.

PubMed

Laird, E; Shannon, T; Crowley, V E F; Healy, M

2017-11-01

There have been few published reports of visualising vitamin D status at a micro level, i.e., within large individual urban centres of countries. To produce a visual map of the vitamin D status [25-hydroxy vitamin D-25(OH)D] of a large urban centre (n > 350,000) incorporating the regions of Dublin city that constitute the general practitioner catchment area of a large academic teaching adult hospital. An observational investigation of 5287 free living Irish adults (>18 years). Approximately, 15.2 % of those sampled in the winter period (October-February) were vitamin D deficient (<30 nmol/L) compared with 10.8 % of those sampled in the summer period (March-September). Vitamin D tests requested from the most social economically deprived urban locations (Dublin 8 and Lucan postal districts) had the highest rates of deficiency (23.5 and 20.4 %, respectively, both seasons). On average, females had a significantly higher 25(OH)D concentration compared with males (57.9 vs 52.3 nmol/L, respectively), while the younger participants (18-50 years) mean 25(OH)D concentration was 27 % lower in winter and 20.7 % lower in summer in comparison with the older participants (>50 years) (P < 0.0001). For the first time in Ireland, a visual depiction of data can be used to aid in the rapid identification of vitamin D status trends within a major urban area. These findings provide useful data to help inform public health policy regarding endemic vitamin D insufficiency to help target the population groups and resident location areas most at risk.

Using Inquiry-Based Instructional Strategies to Increase Student Achievement in 3rd Grade Social Studies

ERIC Educational Resources Information Center

McRae-Jones, Wanda Joycelyn

2017-01-01

21st Century skills such as critical-thinking and problem-solving skills are very important when it comes to Science Technology Engineering and Mathematics or STEM. But those same skills should be integrated in social studies. The impact of students' learning in social studies as a result of implementing inquiry-based instructional strategies was…

Residence Life and the New Student Experience, 3rd Edition. The First-Year Experience Monograph Series No. 5

ERIC Educational Resources Information Center

Zeller, William J., Ed.

2008-01-01

Residence life programs play a key role in recruiting students, helping them make a successful transition to a new institution, and in retaining them, whether students are enrolling for the first time, transferring from another institution, or entering graduate school. Chapters in this book address theories of learning and development, new…

Touch the Future: Discovering Abilities through Technology for Living, Learning, Working and Playing. Southeast Regional Conference (3rd, Atlanta, Georgia, April 10-12, 1991).

ERIC Educational Resources Information Center

Georgia State Dept. of Human Resources, Atlanta. Div. of Rehabilitation Services.

This packet of materials was originally intended for participants in a 1991 conference on assistive technology for the disabled. After a detailed listing of the conference schedule, individual sections provide abstracts, biographical sketches, and summaries concerning the following conference topics: blending, computer labs, family, grants and…

Developing an Aquaponics System to Learn Sustainability and Social Compromise Skills

ERIC Educational Resources Information Center

Duarte, Abel J.; Malheiro, Benedita; Ribeiro, Cristina; Silva, Manuel F.; Ferreira, Paulo; Guedes, Pedro

2015-01-01

The goal of this project, one of the proposals of the EPS@ISEP Spring 2014, was to develop an Aquaponics System. Over recent years Aquaponics systems have received increased attention since they contribute to reduce the strain on resources within 1st and 3rd world countries. Aquaponics is the combination of Hydroponics and Aquaculture, mimicking a…

Political Learning Processes: On the Difficult Role of Critical Intellectuals in Social Movements

ERIC Educational Resources Information Center

Hawel, Marcus; Kalmring, Stefan

2015-01-01

In this article the authors try to elaborate an explicit connection between social theories in relation to the role of intellectuals in social movements. These should view themselves as educational movements if they seek to be successful. By so doing they could avoid either inventing the wheel for the 2nd or 3rd time "afresh" or moving…

Use of Online Information Resources by RMIT University Economics, Finance, and Marketing Students Participating in a Cooperative Education Program

ERIC Educational Resources Information Center

Costa, Cathy

2009-01-01

This paper examines the use of online information resources by Economics, Finance, and Marketing 3rd year students in a cooperative education program and explores some possible factors and issues that influence how students use these resources. The nature of Work Integrated Learning (WIL) programs, the business information environment, and the…

Project CRISS[R] (CReating Independence through Student-owned Strategies). What Works Clearinghouse Intervention Report

ERIC Educational Resources Information Center

What Works Clearinghouse, 2010

2010-01-01

Project CRISS[R] (CReating Independence through Student-owned Strategies) is a professional development program for teachers that aims to improve reading, writing, and learning for 3rd- through 12th-grade students. The implementation of Project CRISS[R] does not require a change in the curriculum or materials being used in the classroom, but…

Cross-Informant Agreement of Children's Social-Emotional Skills: An Investigation of Ratings by Teachers, Parents, and Students from a Nationally Representative Sample

ERIC Educational Resources Information Center

Gresham, Frank M.; Elliott, Stephen N.; Metallo, Sarah; Byrd, Shelby; Wilson, Elizabeth; Cassidy, Kaitlan

2018-01-01

This study examines the agreement across informant pairs of teachers, parents, and students regarding the students' social-emotional learning (SEL) competencies. Two student subsamples representative of the social skills improvement system (SSIS) SEL edition rating forms national standardization sample were examined: first, 168 students (3rd to…

Motivation, Comprehensibility, and Accentedness in L2 Spanish: Investigating Motivation as a Time-Varying Predictor of Pronunciation Development

ERIC Educational Resources Information Center

Nagle, Charles

2018-01-01

This study examined relationships between language learning motivation and the longitudinal development of second language (L2) pronunciation. Twenty-six English-speaking learners of Spanish recorded a simplified picture description task 5 times over a year-long period spanning their 2nd, 3rd, and 4th semesters of Spanish language instruction.…

Improving Reading Comprehension in Kindergarten through 3rd Grade: IES Practice Guide. NCEE 2010-4038

ERIC Educational Resources Information Center

Shanahan, Timothy; Callison, Kim; Carriere, Christine; Duke, Nell K.; Pearson, P. David; Schatschneider, Christopher; Torgesen, Joseph

2010-01-01

Strong reading comprehension skills are central not only to academic and professional success, but also to a productive social and civic life. These skills build the capacity to learn independently, to absorb information on a variety of topics, to enjoy reading, and to experience literature more deeply. Despite the growing demand for highly…

The Educational Development of Students Following Participation in a Pre-School Programme in a Disadvantaged Area in Ireland. Studies and Evaluation Papers 12.

ERIC Educational Resources Information Center

Kellaghan, Thomas; Greaney, Betty Jane

This longitudinal study evaluated the effects of a preschool project designed to serve children between 3 and 5 years of age in a disadvantaged inner-city area in Dublin, Ireland. The preschool, established in 1969, emphasized the development of children's cognitive skills and established structures to increase parents' involvement in their…

Medical Student Perceptions of the Learning Environment in Medical School Change as Students Transition to Clinical Training in Undergraduate Medical School.

PubMed

Dunham, Lisette; Dekhtyar, Michael; Gruener, Gregory; CichoskiKelly, Eileen; Deitz, Jennifer; Elliott, Donna; Stuber, Margaret L; Skochelak, Susan E

2017-01-01

Phenomenon: The learning environment is the physical, social, and psychological context in which a student learns. A supportive learning environment contributes to student well-being and enhances student empathy, professionalism, and academic success, whereas an unsupportive learning environment may lead to burnout, exhaustion, and cynicism. Student perceptions of the medical school learning environment may change over time and be associated with students' year of training and may differ significantly depending on the student's gender or race/ethnicity. Understanding the changes in perceptions of the learning environment related to student characteristics and year of training could inform interventions that facilitate positive experiences in undergraduate medical education. The Medical School Learning Environment Survey (MSLES) was administered to 4,262 students who matriculated at one of 23 U.S. and Canadian medical schools in 2010 and 2011. Students completed the survey at the end of each year of medical school as part of a battery of surveys in the Learning Environment Study. A mixed-effects longitudinal model, t tests, Cohen's d effect size, and analysis of variance assessed the relationship between MSLES score, year of training, and demographic variables. After controlling for gender, race/ethnicity, and school, students reported worsening perceptions toward the medical school learning environment, with the worst perceptions in the 3rd year of medical school as students begin their clinical experiences, and some recovery in the 4th year after Match Day. The drop in MSLES scores associated with the transition to the clinical learning environment (-0.26 point drop in addition to yearly change, effect size = 0.52, p < .0001) is more than 3 times greater than the drop between the 1st and 2nd year (0.07 points, effect size = 0.14, p < .0001). The largest declines were from items related to work-life balance and informal student relationships. There was some, but not complete, recovery in perceptions of the medical school learning environment in the 4th year. Insights: Perceptions of the medical school learning environment worsen as students continue through medical school, with a stronger decline in perception scores as students' transition to the clinical learning environment. Students reported the greatest drop in finding time for outside activities and students helping one another in the 3rd year. Perceptions differed based on gender and race/ethnicity. Future studies should investigate the specific features of medical schools that contribute most significantly to student perceptions of the medical school learning environment, both positive and negative, to pinpoint potential interventions and improvements.

Asynchronous Learning Sources in a High-Tech Organization

ERIC Educational Resources Information Center

Bouhnik, Dan; Giat, Yahel; Sanderovitch, Yafit

2009-01-01

Purpose: The purpose of this study is to characterize learning from asynchronous sources among research and development (R&D) personnel. It aims to examine four aspects of asynchronous source learning: employee preferences regarding self-learning; extent of source usage; employee satisfaction with these sources and the effect of the sources on the…

IRETHERM: The geothermal energy potential of Irish radiothermal granites

NASA Astrophysics Data System (ADS)

Farrell, Thomas; Jones, Alan; Muller, Mark; Feely, Martin; Brock, Andrew; Long, Mike; Waters, Tim

2014-05-01

The IRETHERM project is developing a strategic understanding of Ireland's deep geothermal energy potential through integrated modelling of new and existing geophysical and geological data. One aspect of IRETHERM's research focuses on Ireland's radiothermal granites, where increased concentrations of radioelements provide elevated heat-production (HP), surface heat-flow (SHF) and subsurface temperatures. An understanding of the contribution of granites to the thermal field of Ireland is important to assessing the geothermal energy potential of this low-enthalpy setting. This study focuses on the Galway granite in western Ireland, and the Leinster and the buried Kentstown granites in eastern Ireland. Shallow (<250 m) boreholes were drilled into the exposed Caledonian Leinster and Galway granites as part of a 1980's geothermal project. These studies yielded HP = 2-3 μWm-3 and HF = 80 mWm-2 at the Sally Gap borehole in the Northern Units of the Leinster granite, to the SW of Dublin. In the Galway granite batholith, on the west coast of Ireland, the Costelloe-Murvey granite returned HP = 7 μWm-3 and HF = 77 mWm-2, measured at the Rossaveal borehole. The buried Kentstown granite, 35 km NW of Dublin, has an associated negative Bouguer anomaly and was intersected by two mineral exploration boreholes at depths of 660 m and 490 m. Heat production is measured at 2.4 μWm-3 in core samples taken from the weathered top 30 m of the granite. The core of this study consists of a program of magnetotelluric (MT) and audio-magnetotelluric (AMT) data acquisition across the three granite bodies, over three fieldwork seasons. MT and AMT data were collected at 59 locations along two profiles over the Leinster granite. Preliminary results show that the northern units of the Leinster granite (40 km SW of Dublin) extend to depths of 2-5 km. Preliminary results from the southern profile suggest a greater thickness of granite to a depth of 6-9 km beneath the Tullow pluton, 75 km SW of Dublin. Over the Galway granite, MT and AMT data have been collected at a total of 75 sites (33 consist of only AMT data acquisition, with both MT and AMT recorded at the remaining 42). Preliminary results show a deep resistor extending to depths of 15-20 km beneath the central block, with the resistive upper layer extending to depths of 3.5-7 km west of the Shannawona fault, a major structure that cuts the batholith. MT and AMT data acquired along a profile at 22 locations over the Kentstown granite suggests that this buried granite is at a depth of 400 m beneath the centre of the gravity anomaly. The MT and AMT data will be integrated with gravity and seismic refraction data (in the case of the Leinster granite) to identify deeply penetrating faults, which may provide conduits for hydrothermal fluids, and to produce a robust estimation of the volumetric extent of the granites, which is crucial in defining their geothermal energy potential. Thermal conductivity and geochemical data will be incorporated to constrain the heat contribution of granites to the Irish crust.

Dental students' perceived sources of stress: a multi-country study.

PubMed

Polychronopoulou, Argy; Divaris, Kimon

2009-05-01

The aim of this study was to identify dental students' self-reported sources of stress and to explore the role of specific curricular and institutional differences in the variation of perceived stressors among dental students in Greece, Ireland, Slovenia, Sweden, Spain, and Croatia. A thirty-item modified version of the Dental Environment Stress (DES) questionnaire was administered to all undergraduate students enrolled at six European dental schools selected to reflect geographical, curricular, and professional environment diversity: Athens, Greece; Dublin, Ireland; Ljubljana, Slovenia; Malmö, Sweden; Santiago de Compostela, Spain; and Zagreb, Croatia. Participation varied from 93 percent in Athens to 65 percent in Dublin. A total of 1,492 questionnaires were available for analysis. Univariate analysis and multivariate modelling were used for data analysis. Performance pressure, workload, and self-efficacy beliefs constituted the students' main concerns. In the univariate analysis, student responses differed by country: Swedish students provided the lowestst scores in five out of six DES factors, Spanish students were the most concerned about "clinical training" and "performance pressure," whereas Greek students were the most concerned about "patient treatment." Multivariate modelling revealed that problem-based learning (PBL) was inversely associated with perceived stress for "self-efficacy beliefs" OR (95% CI): 0.66 (0.52, 0.84), "workload" OR (95% CI): 0.58 (0.41, 0.80); and "clinical training" OR (95% CI): 0.69 (0.50, 0.95) when compared to traditional curricula. Students' perceived stressors differed greatly among the six institutions and were associated with both individual (gender, study level) and educational/institutional (curriculum type, class size, educational costs) parameters.

Neurobiological Underpinnings of Math and Reading Learning Disabilities

ERIC Educational Resources Information Center

Ashkenazi, Sarit; Black, Jessica M.; Abrams, Daniel A.; Hoeft, Fumiko; Menon, Vinod

2013-01-01

The primary goal of this review is to highlight current research and theories describing the neurobiological basis of math (MD), reading (RD), and comorbid math and reading disability (MD+RD). We first describe the unique brain and cognitive processes involved in acquisition of math and reading skills, emphasizing similarities and differences in…

R&D Centres in Mexico in an Open Economy: Redefining Operating Practices

ERIC Educational Resources Information Center

de Gortari Rabiela, Rebeca; Corral, Maria Josefa Santos

2004-01-01

Structural changes in Mexico's economy and trade policies have influenced firms' efforts to achieve technological innovation and improve their learning processes. In this context, R&D centres face new challenges in responding to firms' technological needs. The authors analyse how this new environment is affecting the operating practices of R&D…

Cognitive Risk Factors for Specific Learning Disorder: Processing Speed, Temporal Processing, and Working Memory

ERIC Educational Resources Information Center

Moll, Kristina; Göbel, Silke M.; Gooch, Debbie; Landerl, Karin; Snowling, Margaret J.

2016-01-01

High comorbidity rates between reading disorder (RD) and mathematics disorder (MD) indicate that, although the cognitive core deficits underlying these disorders are distinct, additional domain-general risk factors might be shared between the disorders. Three domain-general cognitive abilities were investigated in children with RD and MD:…

Understanding native Russian listeners' errors on an English word recognition test: model-based analysis of phoneme confusion.

PubMed

Shi, Lu-Feng; Morozova, Natalia

2012-08-01

Word recognition is a basic component in a comprehensive hearing evaluation, but data are lacking for listeners speaking two languages. This study obtained such data for Russian natives in the US and analysed the data using the perceptual assimilation model (PAM) and speech learning model (SLM). Listeners were randomly presented 200 NU-6 words in quiet. Listeners responded verbally and in writing. Performance was scored on words and phonemes (word-initial consonants, vowels, and word-final consonants). Seven normal-hearing, adult monolingual English natives (NM), 16 English-dominant (ED), and 15 Russian-dominant (RD) Russian natives participated. ED and RD listeners differed significantly in their language background. Consistent with the SLM, NM outperformed ED listeners and ED outperformed RD listeners, whether responses were scored on words or phonemes. NM and ED listeners shared similar phoneme error patterns, whereas RD listeners' errors had unique patterns that could be largely understood via the PAM. RD listeners had particular difficulty differentiating vowel contrasts /i-I/, /æ-ε/, and /ɑ-Λ/, word-initial consonant contrasts /p-h/ and /b-f/, and word-final contrasts /f-v/. Both first-language phonology and second-language learning history affect word and phoneme recognition. Current findings may help clinicians differentiate word recognition errors due to language background from hearing pathologies.

Early development of language by hand: composing, reading, listening, and speaking connections; three letter-writing modes; and fast mapping in spelling.

PubMed

Berninger, Virginia W; Abbott, Robert D; Jones, Janine; Wolf, Beverly J; Gould, Laura; Anderson-Youngstrom, Marci; Shimada, Shirley; Apel, Kenn

2006-01-01

The first findings from a 5-year, overlapping-cohorts longitudinal study of typical language development are reported for (a) the interrelationships among Language by Ear (listening), Mouth (speaking), Eye (reading), and Hand (writing) in Cohort 1 in 1st and 3rd grade and Cohort 2 in 3rd and 5th grade; (b) the interrelationships among three modes of Language by Hand (writing manuscript letters with pen and keyboard and cursive letters with pen) in each cohort in the same grade levels as (a); and (c) the ability of the 1st graders in Cohort 1 and the 3rd graders in Cohort 2 to apply fast mapping in learning to spell pseudowords. Results showed that individual differences in Listening Comprehension, Oral Expression, Reading Comprehension, and Written Expression are stable developmentally, but each functional language system is only moderately correlated with the others. Likewise, manuscript writing, cursive writing, and keyboarding are only moderately correlated, and each has a different set of unique neuropsychological predictors depending on outcome measure and grade level. Results support the use of the following neuropsychological measures in assessing handwriting modes: orthographic coding, rapid automatic naming, finger succession (grapho-motor planning for sequential finger movements), inhibition, inhibition/switching, and phonemes skills (which may facilitate transfer of abstract letter identities across letter formats and modes of production). Both 1st and 3rd graders showed evidence of fast mapping of novel spoken word forms onto written word forms over 3 brief sessions (2 of which involved teaching) embedded in the assessment battery; and this fast mapping explained unique variance in their spelling achievement over and beyond their orthographic and phonological coding abilities and correlated significantly with current and next-year spelling achievement.

Interactive learning media based on flash for basic electronic engineering development for SMK Negeri 1 Driyorejo - Gresik

NASA Astrophysics Data System (ADS)

Mandigo Anggana Raras, Gustav

2018-04-01

This research aims to produce a product in the form of flash based interactive learning media on a basic electronic engineering subject that reliable to be used and to know students’ responses about the media. The target of this research is X-TEI 1 class at SMK Negeri 1 Driyorejo – Gresik. The method used in this study is R&D that has been limited into seven stages only (1) potential and problems, (2) data collection, (3) product design, (4) product validation, (5) product revision, (6) field test, and (7) analysis and writing. The obtained result is interactive learning media named MELDASH. Validation process used to produce a valid interactive learning media. The result of media validation state that the interactive learning media has a 90.83% rating. Students’ responses to this interactive learning media is really good with 88.89% rating.

R&D Organizations As Learning Systems

ERIC Educational Resources Information Center

Carlsson, Barbara; And Others

1976-01-01

Describes how the authors developed an understanding of the research and development process at the Proctor and Gamble Company by applying David Kolb's Learning Model for Individuals to the organizational learning process. (Available from Alfred P. Sloan School of Management, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139;…

Using Photographs to Probe Students' Understanding of Physical Concepts: The Case of Newton's 3rd Law

ERIC Educational Resources Information Center

Eshach, Haim

2010-01-01

The starting point of the present research is the following question: since we live in an age that makes increasing use of visual representations of all sorts, is not the visual representation a learner constructs a window into his/her understanding of what is or is not being learned? Following this direction of inquiry, the present preliminary…

Naval Aerospace Medical Research Laboratory. 1993 Command History.

DTIC Science & Technology

1994-04-01

selected student naval aviators score differentially on the test battery and are their scores correlated with flight school performance? 58...Ph.D., attended 3rd Meeting of Accelerated Research Initiative, Nenral Constraints on Cognitive Architecture, Learning Research and Development...Shamma, S.E. and Stanny, R.R,, "Models of Cognitive Performance Assessment Tests," Mathematical Modeling and Scientific Compuiing, Vol. 2, pp. 240-245

The Effects of Implementing a Classwide Peer Tutoring Model on Social Approvals and Disapprovals Emitted during Unstructured Free Time

ERIC Educational Resources Information Center

Lawson, Tracy Reilly; Trapenberg, Gabrielle

2007-01-01

This study tested a classwide peer tutoring model using rule-governed responding to teach tutors to accurately present learn units during social studies instruction using a multiple baseline across participants with pre and post intervention probes. Three students, aged 8 to 10, in a self-contained 3rd/4th grade CABAS[R] classroom participated in…

What's Our Position? A Critical Media Literacy Study of Popular Culture Websites with Eighth-Grade Special Education Students

ERIC Educational Resources Information Center

Kesler, Ted; Tinio, Pablo P. L.; Nolan, Brian T.

2016-01-01

This article reports on an action research project with 9 eighth-grade special education students in a self-contained classroom in an urban public school. The 1st author, in collaboration with the classroom teacher (3rd author), taught the students a critical media literacy framework to explore popular culture websites. Students learned to analyze…

The Brady Bunch? New evidence for nominative determinism in patients’ health: retrospective, population based cohort study

PubMed Central

Groarke, John D; Galvin, Zita; McGorrian, Catherine; McCann, Hugh A; Sugrue, Declan; Keelan, Edward; Galvin, Joseph; Blake, Gavin; Mahon, Niall G; O’Neill, James

2013-01-01

Objective To ascertain whether a name can influence a person’s health, by assessing whether people with the surname “Brady” have an increased prevalence of bradycardia. Design Retrospective, population based cohort study. Setting One university teaching hospital in Dublin, Ireland. Participants People with the surname “Brady” in Dublin, determined through use of an online telephone directory. Main outcome measure Prevalence of participants who had pacemakers inserted for bradycardia between 1 January 2007 and 28 February 2013. Results 579 (0.36%) of 161 967 people who were listed on the Dublin telephone listings had the surname “Brady.” The proportion of pacemaker recipients was significantly higher among Bradys (n=8, 1.38%) than among non-Bradys (n=991, 0.61%; P=0.03). The unadjusted odds ratio (95% confidence interval) for pacemaker implantation among individuals with the surname Brady compared with individuals with other surnames was 2.27 (1.13 to 4.57). Conclusions Patients named Brady are at increased risk of needing pacemaker implantation compared with the general population. This finding shows a potential role for nominative determinism in health. PMID:24336304

Verbal Learning and Memory Functions in Adolescents with Reading Disabilities

ERIC Educational Resources Information Center

Oyler, James D.; Obrzut, John E.; Asbjornsen, Arve E.

2012-01-01

The authors of this current study compared the memory performance of adolescent students with specific reading disabilities (RD) with that of typical adolescent readers on a newly developed verbal learning test, the "Bergen-Tucson Verbal Learning Test" (BTVLT). This multiple trial test was designed to measure memory acquisition,…

Learning Strategies of Physics Teacher Candidates: Relationships with Physics Achievement and Class Level

NASA Astrophysics Data System (ADS)

Selçuk, Gamze S.; Çalişkan, Serap; Erol, Mustafa

2007-04-01

Learning strategy concept was introduced in the education field from the development of cognitive psychology. Learning strategies are behaviors and thoughts that a learner engages in during learning which are intended to influence the learner's encoding process. Literature on learning strategies in physics field is very scarce. Participants of the research consist of teacher candidates (n=137) from 1st, 2nd, 3rd, 4th and 5th grade attending Department of Physics Education, Education Faculty of Buca, Dokuz Eylül University in Turkey. Data of this research was collected by ``Scale of Learning Strategies Usage in Physics'' (Cronbach's Alpha=0.93). Mean, Standard Deviation, Analysis of Variance were used to analyze the research data. This paper reports on teacher candidates' learning strategies used in physics education The paper investigates the relationships between learning strategies and physics achievement, class level. Some important outcomes of the research are presented, discussed and certain suggestions are made.

Peer exchange conference, September 19-21, 2006.

DOT National Transportation Integrated Search

2006-09-01

The objectives of the peer exchange process were to: : Learn how the Hawaii Department of Transportation manages and : conducts their Research, Development and Technology Transfer : (RD&TT) Program; also to learn how Montana and Nevada DOTs : man...

Breaking barriers: a competency-based framework for promoting the integration of the pediatrician's education.

PubMed

Naghettini, Alessandra V; Bollela, Valdes R; Costa, Nilce M S C; Salgado, Luciana M R

2011-01-01

To describe the process of integration and revision of a pediatric program curriculum which resulted in the creation of a competency-based framework recommended in the Brazilian National Curricular Guidelines. Quali-quantitative analysis of an intervention evaluating the students and professors' perception of the pediatric program curriculum (focus groups and semi-structured interviews). Results were discussed during teaching development workshops. A competency-based framework was suggested for the pediatric program from the 3rd to the 6th year. The new curriculum was approved, implemented, and reevaluated six months later. Twelve students (12%) from the 3rd to the 6th year participated in the focus groups, and 11 professors (78.5%) answered the questionnaire. Most participants reported lack of integration among the courses, lack of knowledge about the learning goals of the internships, few opportunities of practice, and predominance of theoretical evaluation. In the training workshops, a competency-based curriculum was created after pediatrics and collective health professors reached an agreement. The new curriculum was focused on general competency, learning goals, opportunities available to learn these goals, and evaluation system. After six months, 93% (104/112) of students and 79% (11/14) of professors reported greater integration of the program and highlighted the inclusion of the clinical performance evaluation. The collective creation of a competency-based curriculum promoted higher satisfaction of students and professors. After being implemented, the new curriculum was considered to integrate the teaching practices and contents, improving the quality of the clinical performance evaluation.

Skierarchy: Extending the Power of Crowdsourcing Using a Hierarchy of Domain Experts, Crowd and Machine Learning

DTIC Science & Technology

2012-11-01

college background and good reading comprehension skills in English, and bring to them to the office space to work for us full-time on micro-tasks. This...reasonable reading comprehension skills in English. The expert spent only 1/3rd the time as each member of the crowd in the entire annotation process...3. DATES COVERED 00-00-2012 to 00-00-2012 4. TITLE AND SUBTITLE Skierarchy: Extending the Power of Crowdsourcing Using a Hierarchy of Domain

NREL and General Motors Announce R&D Partnership to Reduce Cost of

Science.gov Websites

modeling studies to a multiyear National Fuel Cell Electric Vehicle Learning Demonstration. Data from the Learning Demonstration were sent to the National Fuel Cell Technology Evaluation Center (NFCTEC), a data

E-Learning Platform for Education Innovation: A Case for Botswana

ERIC Educational Resources Information Center

Marumo, Rapelang; Sehurutshi, Richard; Wangombe, Kabanya

2009-01-01

This article intends to investigate the challenges of e-learning implementation with an emphasis on education innovation. The Botswana government imports technology rather than developing it in-house through or in association with a well-developed national research and development (R&D) centre. In simple terms, e-learning is the delivery of…

Maternal Stress in Nonverbal Learning Disorder: A Comparison with Reading Disorder

ERIC Educational Resources Information Center

Antshel, Kevin M.; Joseph, Guy-Ronald

2006-01-01

Maternal stress was assessed in mothers of children ages 8 to 11 years with learning disorders (LD). Age-, gender-, and IQ-matched children with reading disorders (RD; n = 31), children with nonverbal learning disorders (NVLD; n = 21), and typically developing control participants (n = 23) participated. Mothers of children with LD reported higher…

Embedded Incremental Feature Selection for Reinforcement Learning

DTIC Science & Technology

2012-05-01

Prior to this work, feature selection for reinforce- ment learning has focused on linear value function ap- proximation ( Kolter and Ng, 2009; Parr et al...InProceed- ings of the the 23rd International Conference on Ma- chine Learning, pages 449–456. Kolter , J. Z. and Ng, A. Y. (2009). Regularization and feature

Armed To Learn: Aiming At California K 12 School Gun Policy

DTIC Science & Technology

2016-03-01

involvement in, or presence of, any militia. In District of Columbia v. Heller in 2008, the Supreme Court changed the long-standing collective rights...research focused on decision-making processes that are based on risk management principles fostered by the Insurance Institute of America. Risk...Management, 3rd ed. (Malvern, PA: Insurance Institute of America, 2003), http://www.theinstitutes.org/guide/designations/associate-risk-management

JPRS Report China.

DTIC Science & Technology

1988-09-19

40050343 Beijing GUANGMING RIBAO in Chinese 22Jun88p4 [By Xu Binghe 1776 3521 0735] [Text] This year marks the 10th anniversary of the 3rd Plenary...foreign policy." More than 30 persons from the Foreign Affairs College, other institu- tions of higher learning and research units in Beijing ...bold, enlightened, dynamic and effective way." 9411 Central Party School Symposium on Political Development Strategy 40050341c Beijing GUANGMING

International development of traditional medicine / complementary and alternative medicine research--what can Europe learn?

PubMed

Hök, Johanna; Lewith, George; Weidenhammer, Wolfgang; Santos-Rey, Koldo; Fønnebø, Vinjar; Wiesener, Solveig; Falkenberg, Torkel

2012-01-01

The aim of this study was to analyse global research and development (R&D) strategies for traditional medicine (TM) and complementary and alternative medicine (CAM) across the world to learn from previous and on-going activities. 52 representatives within CAMbrella nominated 43 key international stakeholders (individuals and organisations) and 15 of these were prioritised. Information from policy documents including mission statements, R&D strategies and R&D activities were collected in combination with personal interviews. Data were analysed using the principles of content analysis. Key stakeholders vary greatly in terms of capacity, mission and funding source (private/public). They ranged from only providing research funding to having a comprehensive R&D and communication agenda. A common shift in R&D strategy was noted; whereas 10 years ago research focused mainly on exploring efficacy and mechanisms, today the majority of stakeholders emphasise the importance of a broad spectrum of research, including methodologies exploring context, safety and comparative effectiveness. The scarce public investment in this field in Europe stands in stark contrast to the large investments found in Australia, Asia and North America. There is an emerging global trend supporting a broad research repertoire, including qualitative and comparative effectiveness research. This trend should be considered by the EU given the experience and the substantial research funding committed by the included stakeholders. To facilitate international collaborative efforts and minimise the risk of investment failure, we recommend the formation of a centralised EU CAM research centre fostering a broad CAM R&D agenda with the responsibility for implementing the relevant findings of CAMbrella.

Growth in Rapid Automatized Naming from Grades K to 8 in Children with Math or Reading Disabilities

ERIC Educational Resources Information Center

Mazzocco, Michèle M. M.; Grimm, Kevin J.

2013-01-01

Rapid automatized naming (RAN) is widely used to identify reading disabilities (RD) and has recently been considered a potential predictor of risk for mathematics learning disabilities (MLD). Here we longitudinally examine RAN performance from Grades K to 8, to view how growth on RAN response time differs for children with RD versus MLD. Across…

Usage of unscheduled hospital care by homeless individuals in Dublin, Ireland: a cross-sectional study

PubMed Central

Cullivan, Sarah; Sears, Jess; Lawlee, Ann Marie; Browne, Joe; Kieran, Jennifer; Segurado, Ricardo; O’Carroll, Austin; O’Reilly, Fiona; Creagh, Donnacha; Bergin, Colm; Kenny, Rose Anne; Byrne, Declan

2017-01-01

Objectives Homeless people lack a secure, stable place to live and experience higher rates of serious illness than the housed population. Studies, mainly from the USA, have reported increased use of unscheduled healthcare by homeless individuals. We sought to compare the use of unscheduled emergency department (ED) and inpatient care between housed and homeless hospital patients in a high-income European setting in Dublin, Ireland. Setting A large university teaching hospital serving the south inner city in Dublin, Ireland. Patient data are collected on an electronic patient record within the hospital. Participants We carried out an observational cross-sectional study using data on all ED visits (n=47 174) and all unscheduled admissions under the general medical take (n=7031) in 2015. Primary and secondary outcome measures The address field of the hospital’s electronic patient record was used to identify patients living in emergency accommodation or rough sleeping (hereafter referred to as homeless). Data on demographic details, length of stay and diagnoses were extracted. Results In comparison with housed individuals in the hospital catchment area, homeless individuals had higher rates of ED attendance (0.16 attendances per person/annum vs 3.0 attendances per person/annum, respectively) and inpatient bed days (0.3 vs 4.4 bed days/person/annum). The rate of leaving ED before assessment was higher in homeless individuals (40% of ED attendances vs 15% of ED attendances in housed individuals). The mean age of homeless medical inpatients was 44.19 years (95% CI 42.98 to 45.40), whereas that of housed patients was 61.20 years (95% CI 60.72 to 61.68). Homeless patients were more likely to terminate an inpatient admission against medical advice (15% of admissions vs 2% of admissions in homeless individuals). Conclusion Homeless patients represent a significant proportion of ED attendees and medical inpatients. In contrast to housed patients, the bulk of usage of unscheduled care by homeless people occurs in individuals aged 25–65 years. PMID:29196477

Usage of unscheduled hospital care by homeless individuals in Dublin, Ireland: a cross-sectional study.

PubMed

Ní Cheallaigh, Clíona; Cullivan, Sarah; Sears, Jess; Lawlee, Ann Marie; Browne, Joe; Kieran, Jennifer; Segurado, Ricardo; O'Carroll, Austin; O'Reilly, Fiona; Creagh, Donnacha; Bergin, Colm; Kenny, Rose Anne; Byrne, Declan

2017-12-01

Homeless people lack a secure, stable place to live and experience higher rates of serious illness than the housed population. Studies, mainly from the USA, have reported increased use of unscheduled healthcare by homeless individuals.We sought to compare the use of unscheduled emergency department (ED) and inpatient care between housed and homeless hospital patients in a high-income European setting in Dublin, Ireland. A large university teaching hospital serving the south inner city in Dublin, Ireland. Patient data are collected on an electronic patient record within the hospital. We carried out an observational cross-sectional study using data on all ED visits (n=47 174) and all unscheduled admissions under the general medical take (n=7031) in 2015. The address field of the hospital's electronic patient record was used to identify patients living in emergency accommodation or rough sleeping (hereafter referred to as homeless). Data on demographic details, length of stay and diagnoses were extracted. In comparison with housed individuals in the hospital catchment area, homeless individuals had higher rates of ED attendance (0.16 attendances per person/annum vs 3.0 attendances per person/annum, respectively) and inpatient bed days (0.3 vs 4.4 bed days/person/annum). The rate of leaving ED before assessment was higher in homeless individuals (40% of ED attendances vs 15% of ED attendances in housed individuals). The mean age of homeless medical inpatients was 44.19 years (95% CI 42.98 to 45.40), whereas that of housed patients was 61.20 years (95% CI 60.72 to 61.68). Homeless patients were more likely to terminate an inpatient admission against medical advice (15% of admissions vs 2% of admissions in homeless individuals). Homeless patients represent a significant proportion of ED attendees and medical inpatients. In contrast to housed patients, the bulk of usage of unscheduled care by homeless people occurs in individuals aged 25-65 years. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Giocampus school: a "learning through playing" approach to deliver nutritional education to children.

PubMed

Rosi, Alice; Brighenti, Furio; Finistrella, Viviana; Ingrosso, Lisa; Monti, Giorgia; Vanelli, Maurizio; Vitale, Marco; Volta, Elio; Scazzina, Francesca

2016-01-01

To improve nutritional knowledge of children, single-group educational interventions with pre/post knowledge assessment were performed in primary schools in Parma, Italy, participating to the Giocampus Program. A total of 8165 children (8-11 years old) of 3rd, 4th and 5th grades of primary school were involved in 3 hours per class nutritional lessons, with specifically designed games and activities for each school grade. To evaluate children learning, a questionnaire was administered before and after three months of educational intervention. A total of 16330 questionnaires were analysed. Children nutritional knowledge significantly increased (p< 0.001) in all school grades. The integrated "learning through playing" approach, including the educational figures, tools and games, was successful in improving children's nutritional knowledge. A stable integration of this method in primary school settings could prepare a new generation of citizens, better educated on health-promotion lifestyles.

Digital Libraries and the Problem of Purpose [and] On DigiPaper and the Dissemination of Electronic Documents [and] DFAS: The Distributed Finding Aid Search System [and] Best Practices for Digital Archiving: An Information Life Cycle Approach [and] Mapping and Converting Essential Federal Geographic Data Committee (FGDC) Metadata into MARC21 and Dublin Core: Towards an Alternative to the FGDC Clearinghouse [and] Evaluating Website Modifications at the National Library of Medicine through Search Log analysis.

ERIC Educational Resources Information Center

Levy, David M.; Huttenlocher, Dan; Moll, Angela; Smith, MacKenzie; Hodge, Gail M.; Chandler, Adam; Foley, Dan; Hafez, Alaaeldin M.; Redalen, Aaron; Miller, Naomi

2000-01-01

Includes six articles focusing on the purpose of digital public libraries; encoding electronic documents through compression techniques; a distributed finding aid server; digital archiving practices in the framework of information life cycle management; converting metadata into MARC format and Dublin Core formats; and evaluating Web sites through…

Mapping and converting essential Federal Geographic Data Committee (FGDC) metadata into MARC21 and Dublin Core: towards an alternative to the FGDC Clearinghouse

USGS Publications Warehouse

Chandler, A.; Foley, D.; Hafez, A.M.

2000-01-01

The purpose of this article is to raise and address a number of issues related to the conversion of Federal Geographic Data Committee metadata into MARC21 and Dublin Core. We present an analysis of 466 FGDC metadata records housed in the National Biological Information Infrastructure (NBII) node of the FGDC Clearinghouse, with special emphasis on the length of fields and the total length of records in this set. One of our contributions is a 34 element crosswalk, a proposal that takes into consideration the constraints of the MARC21 standard as implemented in OCLC's World Cat and the realities of user behavior.

Evaluation of BAUER K220 High Pressure Breathing Air Compressor

DTIC Science & Technology

1990-03-01

switch , intermediate 6 Inter-cooler lstf2nd stage pressure lst/2nd stage 7 Inter-cooler 2nd/3rd stage 25 Pressure switch , intermediate 8 Inter-cooler...3rd/4th stage pressure 2nd/3rd stage 9 After-cooler 26 Pressure switch , intermediate 10 Inter-filter 2nd/3rd stage pressure 3rd/4th stage 11 Inter...filter 3rd/4th stage 27 Temperature switch 4th stage 12 Oil and water separator 28 Final pressure switch . 13 Safety valve 1st stage 29 3/2-way solenoid

Helping science to succeed: improving processes in R&D.

PubMed

Sewing, Andreas; Winchester, Toby; Carnell, Pauline; Hampton, David; Keighley, Wilma

2008-03-01

Bringing drugs to the market remains a costly and, until now, often unpredictable challenge. Although understanding the underlying science is key to further progress, our imperfect knowledge of disease and complex biological systems leaves excellence in execution as the most tangible lever to sustain our serendipitous approach to drug discovery. The problems encountered in pharmaceutical R&D are not unique, but to learn from other industries it is important to recognise similarity, rather than differences, and to advance industrialisation of R&D beyond technology and automation. Tools like Lean and Six Sigma, already applied to increase business excellence across diverse organisations, can equally be introduced to pharmaceutical R&D and offer the potential to transform operations without large-scale investment.

Medical humanities: a closer look at learning.

PubMed

Patterson, A; Sharek, D; Hennessy, M; Phillips, M; Schofield, S

2016-06-01

The inclusion of medical humanities with medical curricula is a question that has been the focus of attention for many within the evolving field. This study addressed the question from a medical education perspective and aimed to investigate what students at Trinity College Dublin learned from participating in a short medical humanities student-selected module in their first year of an undergraduate medical programme. A total of 156 students provided a written reflection on a memorable event that occurred during their student-selected module. The reflections were analysed using the Reflection Evaluation for Learners' Enhanced Competencies Tool (REFLECT) and through qualitative thematic analysis of the written reflections. Evidence of learning from the REFLECT quantitative analysis showed that 50% of students displayed higher levels of reflection when describing their experience. The reflection content analysis supported the heterogeneous nature of learning outcome for students, with evidence to support the idea that the module provided opportunities for students to explore their beliefs, ideas and feelings regarding a range of areas outside their current experience or world view, to consider the views of others that they may have not previously been aware of, to reflect on their current views, and to consider their future professional practice. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Anxiety and Depression in Children with Nonverbal Learning Disabilities, Reading Disabilities, or Typical Development

ERIC Educational Resources Information Center

Mammarella, Irene C.; Ghisi, Marta; Bomba, Monica; Bottesi, Gioia; Caviola, Sara; Broggi, Fiorenza; Nacinovich, Renata

2016-01-01

The main goal of the present study was to shed further light on the psychological characteristics of children with different learning disability profiles aged between 8 and 11 years, attending from third to sixth grade. Specifically, children with nonverbal learning disabilities (NLD), reading disabilities (RD), or a typical development (TD) were…

Selecting At-Risk Readers in First Grade for Early Intervention: A Two-Year Longitudinal Study of Decision Rules and Procedures

ERIC Educational Resources Information Center

Compton, Donald L.; Fuchs, Douglas; Fuchs, Lynn S.; Bryant, Joan D.

2006-01-01

Response to intervention (RTI) models for identifying learning disabilities rely on the accurate identification of children who, without Tier 2 tutoring, would develop reading disability (RD). This study examined 2 questions concerning the use of 1st-grade data to predict future RD: (1) Does adding initial word identification fluency (WIF) and 5…

Conference on the Neurobiology of Learning and Memory (3rd)

DTIC Science & Technology

1988-09-23

TREATMENT IN PARADOXICAL SLEEP I. Portell-Cortes, DEPRIVATION PLATFORMS IN RATS . Norpdo-Bernal Area do Psicobiologia Dept. de Psicologia do la Salut Univ...of California Irvine, CA 92717 Irvine, CA 92717 Dr. Robert W. Doty Dr. David Easton Center for Brain Research School of Social Sciences Univ. of...Ignacio Morgado-Bernal Dr. Georges Moroz Area de Psicobiologia CNS Development Psicologia do la Salud CIBA-GEIGY Corp. Univ. Autonoma do Barcelona DEV

Evaluation of the role of incentive structure on student participation and performance in active learning strategies: A comparison of case-based and team-based learning.

PubMed

Carrasco, Gonzalo A; Behling, Kathryn C; Lopez, Osvaldo J

2018-04-01

Student participation is important for the success of active learning strategies, but participation is often linked to the level of preparation. At our institution, we use two types of active learning activities, a modified case-based learning exercise called active learning groups (ALG) and team-based learning (TBL). These strategies have different assessment and incentive structures for participation. Non-cognitive skills are assessed in ALG using a subjective five-point Likert scale. In TBL, assessment of individual student preparation is based on a multiple choice quiz conducted at the beginning of each session. We studied first-year medical student participation and performance in ALG and TBL as well as performance on course final examinations. Student performance in TBL, but not in ALG, was strongly correlated with final examination scores. Additionally, in students who performed in the upper 33rd percentile on the final examination, there was a positive correlation between final examination performance and participation in TBL and ALG. This correlation was not seen in students who performed in the lower 33rd percentile on the final examinations. Our results suggest that assessments of medical knowledge during active learning exercises could supplement non-cognitive assessments and could be good predictors of performance on summative examinations.

Healthy Buddies: a novel, peer-led health promotion program for the prevention of obesity and eating disorders in children in elementary school.

PubMed

Stock, Suzanne; Miranda, Charmaine; Evans, Stacey; Plessis, Suzanne; Ridley, Julia; Yeh, Sophia; Chanoine, Jean-Pierre

2007-10-01

We designed and tested a novel health promotion program for elementary schools that was based on peer teaching from older to younger schoolchildren ("Healthy Buddies"). This prospective pilot study compared the effect of our program (2-3 hours/week, 21 weeks) in 2 Canadian elementary schools (intervention: n = 232 children, the whole school implementing the program; control: n = 151). Older students (4th through 7th grade) were given direct instruction from 1 intervention teacher and were paired with younger students (kindergarten through 3rd grade) for the whole school year. Students in 4th through 7th grade then acted as teachers for their younger "buddies." All lessons included 3 components of healthy living: nutrition, physical activity, and healthy body image. The students first learned how to be positive buddies and learned the 3 components of a healthy life. Thereafter, they learned how to overcome challenges to living a healthy life. Outcome measures (intervention and control schools at the beginning and end of the school year) included validated questionnaires that assessed healthy-living knowledge, behavior and attitude, a 9-minute fitness run, self-competence, body satisfaction, disordered eating symptoms, and anthropometry (BMI, blood pressure, and heart rate). Compared with control students, both older and younger intervention students showed an increase in healthy-living knowledge, behavior, and attitude scores and a smaller increase in systolic blood pressure. BMI and weight increased less in the intervention students in 4th through 7th grade and height more in the intervention students in kindergarten through 3rd grade. Our student-led curriculum improved knowledge not only in older schoolchildren but also in their younger buddies. It also decreased weight velocity in the older students. Student-led teaching may be an efficient, easy-to-implement way of promoting a healthy lifestyle from kindergarten to 7th grade.

Conceptualization of an R&D Based Learning-to-Innovate Model for Science Education

ERIC Educational Resources Information Center

Lai, Oiki Sylvia

2013-01-01

The purpose of this research was to conceptualize an R & D based learning-to-innovate (LTI) model. The problem to be addressed was the lack of a theoretical L TI model, which would inform science pedagogy. The absorptive capacity (ACAP) lens was adopted to untangle the R & D LTI phenomenon into four learning processes: problem-solving via…

The Development of Discovery-Inquiry Learning Model to Reduce the Science Misconceptions of Junior High School Students

ERIC Educational Resources Information Center

Tompo, Basman; Ahmad, Arifin; Muris, Muris

2016-01-01

The main objective of this research was to develop discovery inquiry (DI) learning model to reduce the misconceptions of Science student level of secondary school that is valid, practical, and effective. This research was an R&D (research and development). The trials of discovery inquiry (DI) learning model were carried out in two different…

Leveling the Field on Math and Science Tests for Students with Learning Disabilities. R&D Connections. Number 12

ERIC Educational Resources Information Center

Stone, Elizabeth; Cook, Linda

2009-01-01

Research studies have shown that a smaller percentage of students with learning disabilities participate in state assessments than do their peers without learning disabilities. Furthermore, there is almost always a performance gap between these groups of students on these assessments. It is important to evaluate whether a performance gap on a…

Transcriptional regulation of ABI3- and ABA-responsive genes including RD29B and RD29A in seeds, germinating embryos, and seedlings of Arabidopsis.

PubMed

Nakashima, Kazuo; Fujita, Yasunari; Katsura, Koji; Maruyama, Kyonoshin; Narusaka, Yoshihiro; Seki, Motoaki; Shinozaki, Kazuo; Yamaguchi-Shinozaki, Kazuko

2006-01-01

ABA-responsive elements (ABREs) are cis-acting elements and basic leucine zipper (bZIP)-type ABRE-binding proteins (AREBs) are transcriptional activators that function in the expression of RD29B in vegetative tissue of Arabidopsis in response to abscisic acid (ABA) treatment. Dehydration-responsive elements (DREs) function as coupling elements of ABRE in the expression of RD29A in response to ABA. Expression analysis using abi3 and abi5 mutants showed that ABI3 and ABI5 play important roles in the expression of RD29B in seeds. Base-substitution analysis showed that two ABREs function strongly and one ABRE coupled with DRE functions weakly in the expression of RD29A in embryos. In a transient transactivation experiment, ABI3, ABI5 and AREB1 activated transcription of a GUS reporter gene driven by the RD29B promoter strongly but these proteins activated the transcription driven by the RD29A promoter weakly. In 35S::ABI3 Arabidopsis plants, the expression of RD29B was up-regulated strongly, but that of RD29A was up-regulated weakly. These results indicate that the expression of RD29B having ABREs in the promoter is up-regulated strongly by ABI3, whereas that of RD29A having one ABRE coupled with DREs in the promoter is up-regulated weakly by ABI3. We compared the expression of 7000 Arabidopsis genes in response to ABA treatment during germination and in the vegetative growth stage, and that in 35S::ABI3 plants using a full-length cDNA microarray. The expression of ABI3- and/or ABA-responsive genes and cis-elements in the promoters are discussed.

Cyanidin-3-glucoside extracted from mulberry fruit can reduce N-methyl-N-nitrosourea-induced retinal degeneration in rats.

PubMed

Lee, Seung Hee; Jeong, Eojin; Paik, Sun-Sook; Jeon, Ji Hyun; Jung, Sung Won; Kim, Hyun-Bok; Kim, Muyan; Chun, Myung-Hoon; Kim, In-Beom

2014-01-01

To investigate the effect of cyanidin-3-O-glucoside (C3G) on a rat retinal degeneration (RD) model. Experimental RD was induced in rats by the intraperitoneal injection of N-methyl-N-nitrosourea (MNU) at 50 mg/kg. C3G extracted from mulberry (Morus alba L.) fruit (50 mg/kg) was orally administered, daily for 1, 2 and 4 weeks after MNU injection. The effects of C3G administration on MNU-induced RD retinas were histologically and functionally assessed by hematoxylin and eosin staining and electroretinography (ERG), respectively. The degree of retinal injury in C3G-administered RD rats was evaluated by immunohistochemistry with an antibody against glial fibrillary acidic protein (GFAP). The preferential protective effect of C3G on scotopic vision was examined by western blot analysis. Marked loss of photoreceptors in the outer nuclear layer (ONL) was observed in RD rats at 2 and 4 weeks after MNU injection, while the ONL in the MNU-induced RD rats given C3G was relatively well preserved. Immunohistochemistry with anti-GFAP showed that retinal injury was also reduced in the retinas of the rats given C3G. Functional assessment by using ERG recordings showed that scotopic ERG responses were significantly increased in RD rats given C3G for 4 weeks (p < 0.01) compared with that of untreated RD rats. In the RD rats given short-term C3G (for 1 and 2 weeks), the increase in ERG responses was not significant. In addition, western blot analysis showed that rhodopsin level in the C3G-administered RD retinas significantly increased compared to that in the non-administered RD retinas (p < 0.05), whereas red/green opsin level did not show any significant difference. Long-term administration of C3G extracted from mulberry fruit could structurally reduce photoreceptor damage and functionally improve scotopic visual functions in the RD rat model induced by MNU.

Federal Student Aid Policy: Can We Learn from Experience? Proceedings of the New York Education Policy Seminar (3rd, Albany, New York, October 1985). [and Discussant Comments]. Rockefeller Institute Conference Proceedings, Number 7, Spring 1986.

ERIC Educational Resources Information Center

McPherson, Michael S.; And Others

1985-01-01

This paper examines the problem of determining how effective student aid programs have been in promoting the college enrollment of lower income and disadvantaged students and analyzes the institutional means through which federal aid policies have been implemented. The importance of considering the key role of state and institutional responses to…

Current Research in European Vocational Education and Human Resource Development. Proceedings of the Programme Presented By the Research Network on Vocational Education and Training (VETNET) at the European Conference of Educational Research (ECER) (3rd, Edinburgh, Scotland, September 20-23, 2000).

ERIC Educational Resources Information Center

Manning, Sabine, Ed.; Raffe, David, Ed.

These 24 papers represent the proceedings of a program presented by the research network on vocational education and training (VET). They include "School-Arranged or Market-Governed Workplace Training?" (Ulla Arnell-Gustafsson); "Prospects for Mutual Learning and Transnational Transfer of Innovative Practice in European VET"…

Communication Problems of Learning Disabled Children.

ERIC Educational Resources Information Center

Bryan, Tanis

The presentation reviews the empirical data concerning the existence and types of language problems experienced by learning disabled (LD) and reading disabled (RD) children. An introductory section provides criteria for classification as LD in research samples and a discussion of research data sources in the field of language assessment. Section…

80. GENERAL VIEW TO NORTH ON 3RD AVENUE EL AT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

80. GENERAL VIEW TO NORTH ON 3RD AVENUE EL AT GUN HILL STATION. 7TH AVENUE EL EXPRESS IS VISIBLE ABOVE THE 3RD AVENUE EL WHICH JOINED ONTO THE SAME STRUCTURE AT GUN HILL ROAD. NOTE: GUN HILL ROAD IS THE NORTH TERMINUS OF THE 3RD AVENUE ELEVATED. TRAINS DID NOT CARRY PASSENGERS BEYOND THIS POINT, ALTHOUGH THE 3RD AVENUE TRACK DID EXTEND FURTHER NORTH FOR SWITCHING PURPOSES AND INTO THE YARDS. - Interborough Rapid Transit Company, Third Avenue Elevated Line, Borough of the Bronx, New York County, NY

Ground-water levels, predevelopment ground-water flow, and stream-aquifer relations in the vicinity of the Savannah River Site, Georgia and South Carolina

USGS Publications Warehouse

Clarke, John S.; West, Christopher T.

1998-01-01

Ground-water levels, predevelopment ground-water flow, and stream-aquifer relations in the vicinity of the U.S. Department of Energy Savannah River Site, Georgia and South Carolina, were evaluated as part of a cooperative study between the U.S. Geological Survey, U.S. Department of Energy, and Georgia Department of Natural Resources. As part of this evaluation: (1) ground-water-level fluctuations and trends in three aquifer systems in sediment of Cretaceous and Tertiary age were described and related to patterns of ground-water use and precipitations; (2) a conceptual model ofthe stream-aquifer flow system was developed; (3) the predevelopment ground-water flow system, configuration of potentiometric surfaces, trans-river flow, and recharge-discharge relations were described; and (4) stream-aquifer relations and the influence of river incision on ground-water flow and stream-aquifer relations were described. The 5,147-square mile study area is located in the northern part of the Coastal Plain physiographic province of Georgia and South Carolina. Coastal Plain sediments comprise three aquifer systems consisting of seven aquifers that are separated hydraulically by confining units. The aquifer systems are, in descending order: (1) the Floridan aquifer system?consisting of the Upper Three Runs and Gordon aquifers in sediments of Eocene age; (2) the Dublin aquifer system?consisting of the Millers Pond, upper Dublin, and lower Dublin aquifers in sediments of Paleocene-Late Cretaceous age; and (3) the Midville aquifer system?consisting of the upper Midville and lower Midville aquifers in sediments of Late Cretaceous age. The Upper Three Runs aquifer is the shallowest aquifer and is unconfined to semi-confined throughout most of the study area. Ground-water levels in the Upper Three Runs aquifer respond to a local flow system and are affected mostly by topography and climate. Ground-water flow in the deeper, Gordon aquifer and Dublin and Midville aquifer systems is characterized by local flow near outcrop areas to the north, changing to intermediate flow and then regional flow downdip (southeastward) as the aquifers become more deeply buried. Water levels in these deeper aquifers show a pronounced response to topography and climate in the vicinity of outcrops, and diminish southeastward where the aquifer is more deeply buried. Stream stage and pumpage affect ground-water levels in these deeper aquifers to varying degrees throughout the study area. The geologic characteristics of the Savannah River alluvial valley substantially control the configuration of potentiometric surfaces, ground-water-flow directions, and stream-aquifer relations. Data from 18 shallow borings indicate incision into each aquifer by the paleo Savannah River channel and subsequent infill of permeable alluvium, allowing for direct hydraulic connection between aquifers and the Savannah River along parts of its reach. This hydraulic connection may be the cause of large ground-water discharge to the river near Jackson, S.C., where the Gordon aquifer is in contact with Savannah River alluvium, and also the cause of lows or depressions formed in the potentiometric surfaces of confined aquifers that are in contact with the alluvium. Ground water in these aquifers flows toward the depressions. The influence of the river is diminished downstream where the aquifers are deeply buried, and upstream and downstream ground-water flow is possibly separated by a water divide or 'saddle'. Water-level data indicate that saddle features probably exist in the Gordon aquifer and Dublin aquifer system, and also might be present in the Midville aquifer system. Ground-water levels respond seasonally or in long term to changes in precipitation, evapotranspiration, pumpage, and river stage. Continuous water-level data and water-levels measured in a network of 271 wells during the Spring (May) and Fall (October) in 1992, indicate that seasonal water-level changes generally are

Ireland

NASA Image and Video Library

2017-12-08

On August 7, 2003, the NASA Aqua MODIS instrument acquired this image of Ireland on the first day this summer that most of the island hasn´t been completely obscured by cloud cover. Called the Emerald Isle for a good reason, Ireland is draped in vibrant shades of green amidst the blue Atlantic Ocean and Celtic (south) and Irish (east) Seas. Faint ribbons of blue-green phytoplankton drift in the waters of the Celtic Sea, just south of Dublin. Dublin itself appears as a large grayish-brown spot on the Republic of Ireland´s northeastern coast. This large capital city (population 1.12 million) sits on the River Liffey, effectively splitting the city in half. Northern Ireland´s capital city, Belfast, also sits on a river: the River Lagan. This city, though its population is only a fifth of the size of Dublin´s, is also clearly visible in the image as a grayish-brown spot on the coast of the Irish Sea. Sensor Aqua/MODIS Credit Jeff Schmaltz, MODIS Rapid Response Team, NASA/GSFC For more information go to: visibleearth.nasa.gov/view_rec.php?id=5744 NASA Goddard Space Flight Center is home to the nation's largest organization of combined scientists, engineers and technologists that build spacecraft, instruments and new technology to study the Earth, the sun, our solar system, and the universe. Follow us on Twitter Join us on Facebook

A Resource Manual for Community College Faculty to Support Students with Learning Disabilities

ERIC Educational Resources Information Center

Cheng, Laura

2013-01-01

According to the 23rd Annual Report to Congress, U.S. Department of Education, one out of every five people in the United States has a learning disability (LD). The dropout rate among these students is high, and students with learning disabilities are also less likely to attend 4-year colleges and universities. Although a majority of students with…

Evaluation of undergraduate clinical learning experiences in the subject of pediatric dentistry using critical incident technique.

PubMed

Vyawahare, S; Banda, N R; Choubey, S; Parvekar, P; Barodiya, A; Dutta, S

2013-01-01

In pediatric dentistry, the experiences of dental students may help dental educators better prepare graduates to treat the children. Research suggests that student's perceptions should be considered in any discussion of their education, but there has been no systematic examination of India's undergraduate dental students learning experiences. This qualitative investigation aimed to gather and analyze information about experiences in pediatric dentistry from the students' viewpoint using critical incident technique (CIT). The sample group for this investigation came from all 240 3rd and 4th year dental students from all the four dental colleges in Indore. Using CIT, participants were asked to describe at least one positive and one negative experience in detail. They described 308 positive and 359 negative experiences related to the pediatric dentistry clinic. Analysis of the data resulted in the identification of four key factors related to their experiences: 1) The instructor; 2) the patient; 3) the learning process; and 4) the learning environment. The CIT is a useful data collection and analysis technique that provides rich, useful data and has many potential uses in dental education.

Development of interactive hypermedia software for high school biology: A research and development study

NASA Astrophysics Data System (ADS)

Alturki, Uthman T.

The goal of this research was to research, design, and develop a hypertext program for students who study biology. The Ecology Hypertext Program was developed using Research and Development (R&D) methodology. The purpose of this study was to place the final "product", a CD-ROM for learning biology concepts, in the hands of teachers and students to help them in learning and teaching process. The product was created through a cycle of literature review, needs assessment, development, and a cycle of field tests and revisions. I applied the ten steps of R&D process suggested by Borg and Gall (1989) which, consisted of: (1) Literature review, (2) Needs assessment, (3) Planning, (4) Develop preliminary product, (5) Preliminary field-testing, (6) Preliminary revision, (7) Main field-testing, (8) Main revision, (9) Final field-testing, and (10) Final product revision. The literature review and needs assessment provided a support and foundation for designing the preliminary product---the Ecology Hypertext Program. Participants in the needs assessment joined a focus group discussion. They were a group of graduate students in education who suggested the importance for designing this product. For the preliminary field test, the participants were a group of high school students studying biology. They were the potential user of the product. They reviewed the preliminary product and then filled out a questionnaire. Their feedback and suggestions were used to develop and improve the product in a step called preliminary revision. The second round of field tasting was the main field test in which the participants joined a focus group discussion. They were the same group who participated in needs assessment task. They reviewed the revised product and then provided ideas and suggestions to improve the product. Their feedback were categorized and implemented to develop the product as in the main revision task. Finally, a group of science teachers participated in this study by reviewing the product and then filling out the questionnaire. Their suggestions were used to conduct the final step in R&D methodology, the final product revision. The primary result of this study was the Ecology Hypertext Program. It considered a small attempt to give students an opportunity to learn through an interactive hypertext program. In addition, using the R&D methodology was an ideal procedure for designing and developing new educational products and material.

Science, School Science, and School: Looking at Science Learning in Classrooms from the Perspective of Basil Bernstein's Theory of the Structure of Pedagogic Discourse

NASA Astrophysics Data System (ADS)

Campbell, Ralph Ian

This analytic paper asks one question: How does Basil Bernstein's concept of the structure of pedagogic discourse (SPD) contribute to our understanding of the role of teacher-student interactions in science learning in the classroom? Applying Bernstein's theory of the SPD to an analysis of current research in science education explores the structure of Bernstein's theory as a tool for understanding the challenges and questions related to current concerns about classroom science learning. This analysis applies Bernstein's theory of the SPD as a heuristic through a secondary reading of selected research from the past fifteen years and prompts further consideration of Bernstein's ideas. This leads to a reevaluation of the categories of regulative discourse (RD) and instructional discourse (ID) as structures that frame learning environments and the dynamics of student-teacher interactions, which determine learning outcomes. The SPD becomes a simple but flexible heuristic, offering a useful deconstruction of teaching and learning dynamics in three different classroom environments. Understanding the framing interactions of RD and ID provides perspectives on the balance of agency and expectation, suggesting some causal explanations for the student learning outcomes described by the authors. On one hand, forms of open inquiry and student-driven instruction may lack the structure to ensure the appropriation of desired forms of scientific thinking. On the other hand, well-designed pathways towards the understanding of fundamental concepts in science may lack the forms of more open-ended inquiry that develop transferable understanding. Important ideas emerge about the complex dynamics of learning communities, the materials of learning, and the dynamic role of the teacher as facilitator and expert. Simultaneously, the SPD as a flexible heuristic proves ambiguous, prompting a reevaluation of Bernstein's organization of RD and ID. The hierarchical structure of pedagogic discourse becomes a problematic distinction. Regulative discourse is often more instructional and instructional discourse more instrumental in shaping roles and relationships within the learning community. This analysis suggests an agenda for future classroom research and the education of teachers, capitalizing on the SPD as heuristic and reevaluating the ways that social dynamics and structures for domain-specific learning interact in the realization of classroom learning.

Impact of modellers' decisions on hydrological a priori predictions

NASA Astrophysics Data System (ADS)

Holländer, H. M.; Bormann, H.; Blume, T.; Buytaert, W.; Chirico, G. B.; Exbrayat, J.-F.; Gustafsson, D.; Hölzel, H.; Krauße, T.; Kraft, P.; Stoll, S.; Blöschl, G.; Flühler, H.

2013-07-01

The purpose of this paper is to stimulate a re-thinking of how we, the catchment hydrologists, could become reliable forecasters. A group of catchment modellers predicted the hydrological response of a man-made 6 ha catchment in its initial phase (Chicken Creek) without having access to the observed records. They used conceptually different model families. Their modelling experience differed largely. The prediction exercise was organized in three steps: (1) for the 1st prediction modellers received a basic data set describing the internal structure of the catchment (somewhat more complete than usually available to a priori predictions in ungauged catchments). They did not obtain time series of stream flow, soil moisture or groundwater response. (2) Before the 2nd improved prediction they inspected the catchment on-site and attended a workshop where the modellers presented and discussed their first attempts. (3) For their improved 3rd prediction they were offered additional data by charging them pro forma with the costs for obtaining this additional information. Holländer et al. (2009) discussed the range of predictions obtained in step 1. Here, we detail the modeller's decisions in accounting for the various processes based on what they learned during the field visit (step 2) and add the final outcome of step 3 when the modellers made use of additional data. We document the prediction progress as well as the learning process resulting from the availability of added information. For the 2nd and 3rd step, the progress in prediction quality could be evaluated in relation to individual modelling experience and costs of added information. We learned (i) that soft information such as the modeller's system understanding is as important as the model itself (hard information), (ii) that the sequence of modelling steps matters (field visit, interactions between differently experienced experts, choice of model, selection of available data, and methods for parameter guessing), and (iii) that added process understanding can be as efficient as adding data for improving parameters needed to satisfy model requirements.

Louis I. Dublin and the development of the observational study: the Metropolitan Life Insurance Company natural history (cohort) studies of typhoid fever and scarlet fever.

PubMed

Lilienfeld, David E

2009-06-01

During 1911-1914, using the resources of the Metropolitan Life Insurance Company, Louis I. Dublin conducted two national studies into the survival of those surviving episodes of typhoid fever or scarlet fever. He identified an elevated risk of such mortality, associated with specific causes of death, among those having had typhoid fever but not among the scarlet fever survivors. The studies were methodologically sophisticated, resembling those conducted three to four decades later. The studies appear to have been accepted by the medical and public health communities. However, the absence of modern data processing technology and the lack of financial support for such studies by other investigators precluded the further development of modern epidemiology until World War II.

Robert Dyer Lyons (I 826-1886), microscopist, meteorologist, physician, parliamentarian.

PubMed

Breathnach, Caoimhghin S

2008-06-01

When the attention of Robert Dyer Lyons was drawn to the medical value of the microscope in 1850, he trained himself in its use, and after annually reviewing its recent discoveries he was despatched as chief pathologist to the Army of the East in April 1855. His Report (1856) was a feather in his cap when he returned from the Crimea to Dublin and took up a professorship in the recently founded Catholic University medical school. Popularity as a teacher and success as a physician broadened his interests to national affairs, and he advocated increased funding for university education and re-afforestation. He was elected a Liberal M P for Dublin in 1880 but did not stand for re-election in 1886, the year of his death.

MotorWeek

ScienceCinema

None

2017-12-27

In 2008, PBS's MotorWeek, television's original automotive magazine, visited Argonne's Transportation Technology R&D Center "To learn what it really takes to make clean power sources a viable reality."

Healthcare resource utilization with ixazomib or placebo plus lenalidomide-dexamethasone in the randomized, double-blind, phase 3 TOURMALINE-MM1 study in relapsed/refractory multiple myeloma.

PubMed

Hari, Parameswaran; Lin, Huamao Mark; Zhu, Yanyan; Berg, Deborah; Richardson, Paul G; Moreau, Philippe

2018-05-29

The aim of this analysis was to assess healthcare resource utilization in the pivotal phase 3 TOURMALINE-MM1 study of the oral proteasome inhibitor ixazomib or placebo plus lenalidomide and dexamethasone (Rd) in relapsed and/or refractory multiple myeloma (RRMM). In this double-blind, placebo-controlled, randomized study (NCT01564537), 722 patients with RRMM following 1-3 prior lines of therapy received Rd plus ixazomib (ixazomib-Rd; n = 360) or matching placebo (placebo-Rd; n = 362) until disease progression or unacceptable toxicity. Healthcare resource utilization data were captured on Day 1 of each 28-day cycle, every 4 weeks during follow-up for progression-free survival, and every 12 weeks during subsequent follow-up, and included medical encounters (length of stay, inpatient, outpatient, and reason) and number of missing days from work or other activities for patients and caregivers. Exposure-adjusted rates of hospitalization were similar between the ixazomib-Rd and placebo-Rd arms, at 0.530 and 0.564 per patient year (ppy), respectively, as were outpatient visit rates (3.305 and 3.355 ppy). Mean length of hospitalization per patient was 10.0 and 10.8 days, respectively. In both arms, hospitalization and outpatient visit rates were higher in patients with two or three prior lines of treatment (ixazomib-Rd: 0.632 and 3.909 ppy; placebo-Rd: 0.774 and 3.539 ppy) compared with patients with one prior line (ixazomib-Rd: 0.460 and 2.888 ppy; placebo-Rd: 0.436 and 3.243 ppy). Patients and their caregivers who missed any work or other activity missed a median of 7 and 5 days in the ixazomib-Rd arm, respectively, vs 8 and 4 days with placebo-Rd. The study was not powered for a statistical comparison of healthcare resource utilization between treatment arms, nor did it capture costs associated with utilization of the identified healthcare resources. This pre-specified analysis demonstrated that the all-oral triplet regimen of ixazomib added to Rd did not increase healthcare resource utilization compared with placebo-Rd.

Survey of K-3rd-Grade Teachers' Knowledge of Ear Infections and Willingness to Participate in Prevention Programs

ERIC Educational Resources Information Center

Danhauer, Jeffrey L.; Johnson, Carole E.; Caudle, Abby T.

2011-01-01

Purpose: Ear infections are prevalent in kindergarten through 3rd-grade (K-3rd) children and can affect their performance at school. Chewing gum, when administered by parents and teachers, can help prevent ear infections in children. This pilot study surveyed K-3rd-grade teachers in the Santa Barbara School Districts to assess their knowledge…

75 FR 55313 - Record of Decision (ROD) for Conversion of the 3rd Armored Cavalry Regiment (3rd ACR) to a...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-10

... DEPARTMENT OF DEFENSE Department of the Army Record of Decision (ROD) for Conversion of the 3rd Armored Cavalry Regiment (3rd ACR) to a Stryker Brigade Combat Team (SBCT) at Fort Hood, TX AGENCY: Department of the Army, DoD. ACTION: Notice of Availability (NOA). SUMMARY: The Department of the Army...

Assessing Saudi medical students learning approach using the revised two-factor study process questionnaire.

PubMed

Shaik, Shaffi Ahamed; Almarzuqi, Ahmed; Almogheer, Rakan; Alharbi, Omar; Jalal, Abdulaziz; Alorainy, Majed

2017-08-17

To assess learning approaches of 1st, 2nd, and 3rd-year medical students by using revised two-factor study process questionnaire, and to assess reliability and validity of the questionnaire. This cross-sectional study was conducted at the College of Medicine, Riyadh, Saudi Arabia in 2014. The revised two-factor study process questionnaire (R-SPQ-2F) was completed by 610 medical students of both genders, from foundation (first year), central nervous system (second year), medicine and surgery (third year) courses. The study process was evaluated by computing mean scores of two research study approaches (deep & surface) using student's t-test and one-way analysis of variance. The internal consistency and construct validity of the questionnaire were assessed using Cronbach's α and factor analysis. The mean score of deep approach was significantly higher than the surface approach among participants(t (770) =7.83, p= 0.000) for the four courses. The mean scores of deep approach were significantly higher among participants with higher grade point average (F (2,768) =13.31, p=0.001) along with more number of study hours by participants (F (2,768) =20.08, p=0.001). The Cronbach's α-values of items at 0.70 indicate the good internal consistency of questionnaire used. Factor analysis confirms two factors (deep and surface approaches) of R-SPQ-2F. The deep approach to learning was the primary approach among 1st, 2nd and 3rd-year King Saud University medical students. This study confirms reliability and validity of the revised two-factor study process questionnaire. Medical educators could use the results of such studies to make required changes in the curriculum.

Undergraduate psychiatry students' attitudes towards teaching methods at an Irish university.

PubMed

Jabbar, F; Casey, P; Kelly, B D

2016-11-01

At University College Dublin, teaching in psychiatry includes clinical electives, lectures, small-group and problem-based teaching, consistent with international trends. To determine final-year psychiatry students' attitudes towards teaching methods. We distributed questionnaires to all final-year medical students in two classes (2008 and 2009), after final psychiatry examination (before results) and all of them participated (n = 111). Students' interest in psychiatry as a career increased during psychiatry teaching. Students rated objective structured clinical examination (OSCE) as the most useful element of teaching and examination. The most common learning style was "reflector"; the least common was "pragmatist". Two thirds believed teaching could be improved (increased patient contact) and 89 % reported that experience of psychiatry changed attitudes towards mental illness (increased understanding). Students' preference for OSCEs may reflect the closeness of OSCE as a form of learning to OSCE as a form of assessment: OSCEs both focus on specific clinical skills and help prepare for examinations. Future research could usefully examine the extent to which these findings are university-specific or instructor-dependent. Information on the consistency of various teaching, examination and modularisation methods would also be useful.

The impact of safety rules revisions on safety culture, incident rates, and liability claims in the U.S. railroad industry : a summary of lessons-learned

DOT National Transportation Integrated Search

2003-01-01

The Federal Railroad Administration (FRA) Human Factors Research and Development (R&D) Program sponsored a lessons-learned study to examine the impact of safety rules revision on safety culture, incident rates, and liability claims in the railroad in...

Self-Monitoring Support for Learning to Write

ERIC Educational Resources Information Center

Cho, Kwangsu; Cho, Moon-Heum; Hacker, Douglas J.

2010-01-01

This study examined the role of self-monitoring (SM) support for writing skill improvement in a reciprocal peer review of writing system called scaffolded writing and revision in the disciplines (SWoRD). Based on previous literature on the key role of SM in self-regulated learning, students were provided with opportunities to self-monitor their…

Depression among older people in Europe: the EURODEP studies.

PubMed

Copeland, John R M; Beekman, Aartjan T F; Braam, Arjan W; Dewey, Michael E; Delespaul, Philippe; Fuhrer, Rebecca; Hooijer, Christopher; Lawlor, Brian A; Kivela, Sirkka-Liisa; Lobo, Anthony; Magnusson, Halgrimur; Mann, Anthony H; Meller, Ingeborg; Prince, Martin J; Reischies, Friedel; Roelands, Marc; Skoog, Ingmar; Turrina, Cesare; deVries, Marten W; Wilson, Kenneth C M

2004-02-01

The data from nine centres in Europe which had used the Geriatric Mental Scale (GMS) AGECAT were analysed to compare prevalence of diagnoses in subjects aged 65 years and over living in the community. Levels of depressive illness were: Iceland 8.8%, Liverpool 10.0%; Zaragoza 10.7%; Dublin 11.9%; Amsterdam 12.0%; Berlin 16.5%; London 17.3%; Verona 18.3% and Munich 23.6%. Taking all levels of depression, five high (Amsterdam, Berlin, Munich, London and Verona) and four low (Dublin, Iceland, Liverpool, Zaragoza) scoring centres were identified. Meta-analysis of all 13,808 subjects yielded a mean level of depression of 12.3% (95% CI 11.8-12.9), 14.1% for women (95% CI 13.5-14.8) and 8.6% for men (95% CI 7.9-9.3). Symptom levels varied between centres: 40% of the total study population in Amsterdam reported depressive mood against only 26% in Zaragoza. To incorporate studies from other centres using other methods for depression identification, the EURO-D scale was developed from 12 items of the GMS and validated against other scales and expert diagnosis. A two factor solution emerged, an 'affective suffering factor' and a 'motivation factor'. The EURO-D scale was applied to 14 population based surveys. Depression score tended to increase with age unlike levels of prevalence of depression. Large between centre differences were evident in levels of depression unexplained by age, gender or marital status. These data show that depressive illness defined as suitable for intervention is common among older people in Europe. Opportunities for effective treatment are almost certainly being lost. Levels of depressive symptoms vary significantly between high and low scoring centres, prompting the next phase of this study, an examination of risk factors in Europe.

The Teaching of Mechanical Engineering Design at UCD, Dublin.

ERIC Educational Resources Information Center

Timoney, Seamus

1988-01-01

Describes a design course which stresses the identification of talented students and gives them techniques for synthesis. Explains the course requirements, design and manufacturing functions, and product concept. (YP)

Better together: Simultaneous presentation of speech and gesture in math instruction supports generalization and retention.

PubMed

Congdon, Eliza L; Novack, Miriam A; Brooks, Neon; Hemani-Lopez, Naureen; O'Keefe, Lucy; Goldin-Meadow, Susan

2017-08-01

When teachers gesture during instruction, children retain and generalize what they are taught (Goldin-Meadow, 2014). But why does gesture have such a powerful effect on learning? Previous research shows that children learn most from a math lesson when teachers present one problem-solving strategy in speech while simultaneously presenting a different, but complementary, strategy in gesture (Singer & Goldin-Meadow, 2005). One possibility is that gesture is powerful in this context because it presents information simultaneously with speech. Alternatively, gesture may be effective simply because it involves the body, in which case the timing of information presented in speech and gesture may be less important for learning. Here we find evidence for the importance of simultaneity: 3 rd grade children retain and generalize what they learn from a math lesson better when given instruction containing simultaneous speech and gesture than when given instruction containing sequential speech and gesture. Interpreting these results in the context of theories of multimodal learning, we find that gesture capitalizes on its synchrony with speech to promote learning that lasts and can be generalized.

Clarithromycin (Biaxin)-lenalidomide-low-dose dexamethasone (BiRd) versus lenalidomide-low-dose dexamethasone (Rd) for newly diagnosed myeloma.

PubMed

Gay, Francesca; Rajkumar, S Vincent; Coleman, Morton; Kumar, Shaji; Mark, Tomer; Dispenzieri, Angela; Pearse, Roger; Gertz, Morie A; Leonard, John; Lacy, Martha Q; Chen-Kiang, Selina; Roy, Vivek; Jayabalan, David S; Lust, John A; Witzig, Thomas E; Fonseca, Rafael; Kyle, Robert A; Greipp, Philip R; Stewart, A Keith; Niesvizky, Ruben

2010-09-01

The objective of this case-matched study was to compare the efficacy and toxicity of the addition of clarithromycin (Biaxin) to lenalidomide/low-dose dexamethasone (BiRd) vs. lenalidomide/low-dose dexamethasone (Rd) for newly diagnosed myeloma. Data from 72 patients treated at the New York Presbyterian Hospital-Cornell Medical Center were retrospectively compared with an equal number of matched pair mates selected among patients seen at the Mayo Clinic who received Rd. Case matching was blinded and was performed according to age, gender, and transplant status. On intention-to-treat analysis, complete response (45.8% vs. 13.9%, P < 0.001) and very-good-partial-response or better (73.6% vs. 33.3%, P < 0.001) were significantly higher with BiRd. Time-to-progression (median 48.3 vs. 27.5 months, P = 0.071), and progression-free survival (median 48.3 vs. 27.5 months, P = 0.044) were higher with BiRd. There was a trend toward better OS with BiRd (3-year OS: 89.7% vs. 73.0%, P = 0.170). Main grade 3-4 toxicities of BiRd were hematological, in particular thrombocytopenia (23.6% vs. 8.3%, P = 0.012). Infections (16.7% vs. 9.7%, P = 0.218) and dermatological toxicity (12.5% vs. 4.2%, P = 0.129) were higher with Rd. Results of this case-matched analysis suggest that there is significant additive value when clarithromycin is added to Rd. Randomized phase III trials are needed to confirm these results. © 2010 Wiley-Liss, Inc.

Mathematics Education beyond 2000: Proceedings of the Annual Meeting of the Mathematics Education Research Group of Australasia (23rd, Fremantle, Western Australia, Australia, July 5-9, 2000). Volume 1 [and] Volume 2.

ERIC Educational Resources Information Center

Bana, Jack, Ed.; Chapman, Anne, Ed.

This document contains Volumes 1 and 2 of the proceedings of the 23rd annual conference of the Mathematics Education Research Group of Australasia Incorporated (MERGA) held at Fremantle, Western Australia, July 5-9, 2000. Papers in Volume 1 include: (1) "Bridging Practices: Intertwining Content and Pedagogy in Teaching and Learning To Teach"…

Continuous executive function disruption interferes with application of an information integration categorization strategy.

PubMed

Miles, Sarah J; Matsuki, Kazunaga; Minda, John Paul

2014-07-01

Category learning is often characterized as being supported by two separate learning systems. A verbal system learns rule-defined (RD) categories that can be described using a verbal rule and relies on executive functions (EFs) to learn via hypothesis testing. A nonverbal system learns non-rule-defined (NRD) categories that cannot be described by a verbal rule and uses automatic, procedural learning. The verbal system is dominant in that adults tend to use it during initial learning but may switch to the nonverbal system when the verbal system is unsuccessful. The nonverbal system has traditionally been thought to operate independently of EFs, but recent studies suggest that EFs may play a role in the nonverbal system-specifically, to facilitate the transition away from the verbal system. Accordingly, continuously interfering with EFs during the categorization process, so that EFs are never fully available to facilitate the transition, may be more detrimental to the nonverbal system than is temporary EF interference. Participants learned an NRD or an RD category while EFs were untaxed, taxed temporarily, or taxed continuously. When EFs were continuously taxed during NRD categorization, participants were less likely to use a nonverbal categorization strategy than when EFs were temporarily taxed, suggesting that when EFs were unavailable, the transition to the nonverbal system was hindered. For the verbal system, temporary and continuous interference had similar effects on categorization performance and on strategy use, illustrating that EFs play an important but different role in each of the category-learning systems.

Lessons learned from Ebola Vaccine R&D during a public health emergency.

PubMed

Kieny, Marie-Paule

2018-02-16

In spite of a complete lack of Research and Development (R&D) preparedness, the 2013-2016 West-Africa Ebola experience demonstrated that it is possible to compress R&D timelines to less than a single year, from a more usual decade or longer. This is mostly to be credited to an unprecedented collaborative effort building on the availability of a small number of candidate diagnostic tests, drugs and vaccines that could be moved rapidly into the clinical phase evaluation. The World Health Organization (WHO) led international consultations and activities - including the organization of a successful Ebola vaccine efficacy trial in Guinea - as a contribution to the unprecedented global efforts to control the Ebola epidemic. Since 2015, WHO expert teams and partners are implementing a novel R&D model for emerging infectious pathogens which are the most likely to cause severe outbreaks in the future, and for which no or only few medical countermeasures are available: the WHO R&D Blueprint. The objective for the Blueprint is the fostering of a R&D environment which is prepared for quickly and effectively responding to outbreaks due to emerging infectious disease.

A Proposed Conceptual Framework and Investigation of Upward Feedback Receptivity in Medical Education.

PubMed

Kost, Amanda; Combs, Heidi; Smith, Sherilyn; Klein, Eileen; Kritek, Patricia; Robins, Lynne; Cianciolo, Anna T; Butani, Lavjay; Gigante, Joseph; Ramani, Subha

2015-01-01

WGEA 2015 CONFERENCE ABSTRACT (EDITED). Faculty Perceptions of Receiving Feedback From Third-Year Clerkship Students. Amanda Kost, Heidi Combs, Sherilyn Smith, Eileen Klein, Patricia Kritek, and Lynne Robins. PHENOMENON: In addition to giving feedback to 3rd-year clerkship students, some clerkship instructors receive feedback, requested or spontaneous, from students prior to the clerkship's end. The concept of bidirectional feedback is appealing as a means of fostering a culture of respectful communication and improvement. However, little is known about how teachers perceive this feedback in practice or how it impacts the learning environment. We performed 24 semistructured 30-minute interviews with 3 to 7 attending physician faculty members each in Pediatrics, Internal Medicine, Family Medicine, Surgery, Psychiatry, and Obstetrics and Gynecology who taught in 3rd-year required clerkships during the 2012-2013 academic year. Questions probed teachers' experience with and attitudes toward receiving student feedback. Prompts were used to elicit stories and obtain participant demographics. Interviews were audio-recorded, transcribed, and entered into Dedoose for qualitative analysis. Researchers read transcripts holistically for meaning, designed a coding template, and then independently coded each transcript. A constant comparative approach and regular meetings were used to ensure consistent coding between research team members. Participants ranged in age from 37 to 74, with 5 to 35 years of teaching experience. Seventy-one percent were male, and 83% identified as White. In our preliminary analysis, our informants reported a range of experience in receiving student feedback prior to the end of a clerkship, varying from no experience to having developed mechanisms to regularly request specific feedback about their programs. Most expressed openness to actively soliciting and receiving student feedback on their teaching during the clerkship although many questioned whether this process was feasible. Actual responses to receiving student feedback were mixed. Some reported having received feedback that motivated change, and others rejected the feedback they received on the grounds that it lacked validity or was inappropriate. Others expressed uncertainty about how they would react to student feedback. Faculty expressed a preference for receiving feedback about behaviors and items that were within their control. INSIGHTS: These findings suggest there is opportunity to pilot implementation of a structured student feedback mechanism, separate from teacher evaluations, in selected 3rd-year clerkships. Materials should developed to help faculty solicit, understand, and respond to student feedback and to help students frame and provide the kinds of feedback to teachers that will lead to suggested improvements. Both these endeavors have the potential to improve the clinical learning environment during 3rd-year clerkships through the cultivation of respectful communication and the encouragement of improvement in teaching efforts.

Improving Scientific Metadata Interoperability And Data Discoverability using OAI-PMH

NASA Astrophysics Data System (ADS)

Devarakonda, Ranjeet; Palanisamy, Giri; Green, James M.; Wilson, Bruce E.

2010-12-01

While general-purpose search engines (such as Google or Bing) are useful for finding many things on the Internet, they are often of limited usefulness for locating Earth Science data relevant (for example) to a specific spatiotemporal extent. By contrast, tools that search repositories of structured metadata can locate relevant datasets with fairly high precision, but the search is limited to that particular repository. Federated searches (such as Z39.50) have been used, but can be slow and the comprehensiveness can be limited by downtime in any search partner. An alternative approach to improve comprehensiveness is for a repository to harvest metadata from other repositories, possibly with limits based on subject matter or access permissions. Searches through harvested metadata can be extremely responsive, and the search tool can be customized with semantic augmentation appropriate to the community of practice being served. However, there are a number of different protocols for harvesting metadata, with some challenges for ensuring that updates are propagated and for collaborations with repositories using differing metadata standards. The Open Archive Initiative Protocol for Metadata Handling (OAI-PMH) is a standard that is seeing increased use as a means for exchanging structured metadata. OAI-PMH implementations must support Dublin Core as a metadata standard, with other metadata formats as optional. We have developed tools which enable our structured search tool (Mercury; http://mercury.ornl.gov) to consume metadata from OAI-PMH services in any of the metadata formats we support (Dublin Core, Darwin Core, FCDC CSDGM, GCMD DIF, EML, and ISO 19115/19137). We are also making ORNL DAAC metadata available through OAI-PMH for other metadata tools to utilize, such as the NASA Global Change Master Directory, GCMD). This paper describes Mercury capabilities with multiple metadata formats, in general, and, more specifically, the results of our OAI-PMH implementations and the lessons learned. References: [1] R. Devarakonda, G. Palanisamy, B.E. Wilson, and J.M. Green, "Mercury: reusable metadata management data discovery and access system", Earth Science Informatics, vol. 3, no. 1, pp. 87-94, May 2010. [2] R. Devarakonda, G. Palanisamy, J.M. Green, B.E. Wilson, "Data sharing and retrieval using OAI-PMH", Earth Science Informatics DOI: 10.1007/s12145-010-0073-0, (2010). [3] Devarakonda, R.; Palanisamy, G.; Green, J.; Wilson, B. E. "Mercury: An Example of Effective Software Reuse for Metadata Management Data Discovery and Access", Eos Trans. AGU, 89(53), Fall Meet. Suppl., IN11A-1019 (2008).

Grimsvotn ash plume detection by ground-based elastic Lidar at Dublin Airport on May 2011

NASA Astrophysics Data System (ADS)

Lolli, S.; Martucci, G.; O'Dowd, C.; sauvage, L.; Nolan, P.

2011-12-01

Volcanic emissions comprising steam, ash, and gases are injected into the atmosphere and produce effects affecting Earth's climate. Volcanic ash is composed of non-spherical mineral and metal (particles spanning a large size range. The largest ones are likely to sediment quickly close to the eruption site. The ash component, and sulphate formed by subsequent oxidation of the SO2 occurring in clouds, poses a variety of hazards to humans and machinery on the ground, as well as damage to the aircrafts which fly through the ash layers. To mitigate such hazards the Irish Aviation Authority (IAA) equipped with an ALS Lidar, produced by LEOSPHERE, deployed at Dublin Airport, which provides real-time range-corrected backscatter signal and depolarization ratio profiles allowing the detection and monitoring of ash plumes. On May, 21st 2011, the Grimsvotn Icelandic volcano erupted, sending a plume of ash, smoke and steam 12 km into the air and causing flights to be disrupted at Iceland's main Keflavik airport and at a number of North European airports. Due to upper level global circulation, the ash plume moved from Iceland towards Ireland and North of Scotland, and was detected a number of times by the ALS Lidar above Dublin Airport between May, 21st and 25th. A preliminary analysis of the detected volcanic plume is presented here as well as a preliminary intercomparison of the microphysical and optical characteristics with the Eyjafjallajökull eruption in 2010.

Syphilis serology in pregnancy: an eight-year study (2005-2012) in a large teaching maternity hospital in Dublin, Ireland.

PubMed

McGettrick, Padraig; Ferguson, Wendy; Jackson, Valerie; Eogan, Maeve; Lawless, Mairead; Ciprike, Vaneta; Varughese, Alan; Coulter-Smith, Sam; Lambert, John S

2016-03-01

All cases of positive syphilis serology detected in antenatal and peripartum screening in a large teaching maternity hospital in inner city Dublin, Ireland over an eight-year period (2005-2012 inclusive) were reviewed and included in our study. Demographic, antenatal registration, laboratory (including co-infections), partner serology, treatment and delivery data were recorded in our database. Infant follow-up, treatment and outcome data were also collected. During this period, 194 women had positive syphilis serology, of which 182 completed their pregnancies at the institution. This accounts for 0.28% of the total number of women completing their pregnancies during this time (N = 66038); 79 had no previous diagnosis of infection. There was one case of re-infection during pregnancy. Thirty-two women were co-infected with human immunodeficiency virus, hepatitis B or hepatitis C. There was one case suggestive of congenital syphilis infection. Our study is a comprehensive analysis of the diagnosis, management and clinical outcomes of women testing positive for syphilis infection in pregnancy. It reveals the relatively high prevalence of syphilis infection in the population utilising the maternity services in north inner-city Dublin. It re-enforces the importance of continued active surveillance to prevent morbidity and mortality associated with maternal syphilis infection. It also highlights the importance of strategies such as re-testing high-risk groups and definitive screening of spouse serology. © The Author(s) 2015.

Secondary prevention and cognitive function after stroke: a study protocol for a 5-year follow-up of the ASPIRE-S cohort

PubMed Central

Williams, David; Gaynor, Eva; Bennett, Kathleen; Dolan, Eamon; Callaly, Elizabeth; Large, Margaret; Hickey, Anne

2017-01-01

Introduction Cognitive impairment is common following stroke and can increase disability and levels of dependency of patients, potentially leading to greater burden on carers and the healthcare system. Effective cardiovascular risk factor control through secondary preventive medications may reduce the risk of cognitive decline. However, adherence to medications is often poor and can be adversely affected by cognitive deficits. Suboptimal medication adherence negatively impacts secondary prevention targets, increasing the risk of recurrent stroke and further cognitive decline. The aim of this study is to profile cognitive function and secondary prevention, including adherence to secondary preventive medications and healthcare usage, 5 years post-stroke. The prospective associations between cognition, cardiovascular risk factors, adherence to secondary preventive medications, and rates of recurrent stroke or other cardiovascular events will also be explored. Methods and analysis This is a 5-year follow-up of a prospective study of the Action on Secondary Prevention Interventions and Rehabilitation in Stroke (ASPIRE-S) cohort of patients with stroke. This cohort will have a detailed assessment of cognitive function, adherence to secondary preventive medications and cardiovascular risk factor control. Ethics and dissemination Ethical approval for this study was granted by the Research Ethics Committees at Beaumont Hospital, Dublin and Connolly Hospital, Dublin, Mater Misericordiae University Hospital, Dublin, and the Royal College of Surgeons in Ireland. Findings will be disseminated through presentations and peer-reviewed publications. PMID:28348196

Prevalence and Patterns of Learning Disabilities in School Children.

PubMed

Padhy, Susanta Kumar; Goel, Sonu; Das, Shyam Sinder; Sarkar, Siddharth; Sharma, Vijaylaxmi; Panigrahi, Mahima

2016-04-01

To assess the prevalence and patterns of learning disabilities (LD) in school going children in a northern city of India. The present cross-sectional study comprised of three-staged screening procedure for assessing learning disabilities of 3rd and 4th grade students studying in government schools. The first stage comprised of the teacher identifying at-risk student. In the second stage, teachers assessed at-risk students using Specific Learning Disability-Screening Questionnaire (SLD-SQ). The third stage comprised of assessment of the screen positive students using Brigance Diagnostic Inventory (BDI) part of NIMHANS Index of Specific Learning Disabilities for identifying the cases of LD. A total of 1211 (33.6%) children out of the total screened (n = 3600) were identified as at-risk by the teachers at the first stage. Of them, 360 were found to screen positive on the second stage using SLD-SQ. The most common deficits were missing out words or sentences while reading, misplacing letters or words while reading or writing, and making frequent mistake in spelling while writing or reading. Of these, 108 children were confirmed to have learning disability on the third stage using BDI, which represented 3.08% of the total population. Learning disability is an important concern in young school aged children. Early identification of such students can help in early institution of intervention and suitable modifications in teaching techniques.

Improving Science Achievement and Attitudes of Students with and without Learning Disabilities

ERIC Educational Resources Information Center

Sanders-White, Pamela

2013-01-01

The primary purpose of this study was to investigate the effect of structured note-taking compared to traditional note-taking on the acquisition of scientific knowledge for students with and without learning disabilities (LD) and students with reading difficulties (RD). An additional purpose was to examine whether the two note-taking methods…

Intervention Effects for Students with Comorbid Forms of Learning Disability: Understanding the Needs of Nonresponders

ERIC Educational Resources Information Center

Fuchs, Lynn S.; Fuchs, Douglas; Compton, Donald L.

2013-01-01

In this article, we considered evidence from our intervention research programs on whether students with learning disability (LD) in reading and mathematics (comorbid LD) respond differently to intervention, compared to students with reading LD alone (RD) or to students with mathematics LD alone (MD). The goal was to gain insight into whether…

The Role of Leadership: The Challenge of Knowledge Management and Learning in Knowledge-Intensive Organizations

ERIC Educational Resources Information Center

Mas-Machuca, Marta

2014-01-01

Knowledge and learning are important driving forces for business success and competitiveness, especially in the knowledge-intensive organizations (KIO's) whose core business is to create and sell knowledge (e.g. education, R&D units, and consultancy organizations, among others). Previous works suggested one of the Critical Success Factor (CSF)…

Erratum to "Large-scale mitochondrial COI gene sequence variability reflects the complex colonization history of the invasive soft-shell clam, Mya arenaria (L.) (Bivalvia)" [Estuar. Coast. Shelf Sci. 181 (2016) 256-265

NASA Astrophysics Data System (ADS)

Lasota, Rafal; Pierscieniak, Karolina; Garcia, Pascale; Simon-Bouhet, Benoit; Wolowicz, Maciej

2017-03-01

The publisher regrets a printing error in the last paragraph in the Results section. The correct text should read as follows: Tajima's D, Fu and Li's D* and F*, and Fu's Fs were negative for all American populations, and statistically significant in most cases (Table 3). In most of the European populations the values of neutrality tests were positive, but not statistically significant. The highest positive values of neutrality tests were noted in the populations from Reykjavik (Iceland) and Dublin (Ireland) (Table 3).

The Development of Newtonian Calculus in Britain, 1700-1800

NASA Astrophysics Data System (ADS)

Guicciardini, Niccoló

2003-11-01

Introduction; Overture: Newton's published work on the calculus of fluxions; Part I. The Early Period: 1. The diffusion of the calculus (1700-1730); 2. Developments in the calculus of fluxions (1714-1733); 3. The controversy on the foundations of the calculus (1734-1742); Part II. The Middle Period: 4. The textbooks on fluxions (1736-1758); 5. Some applications of the calculus (1740-1743); 6. The analytic art (1755-1785); Part III. The Reform: 7. Scotland (1785-1809); 8. The Military Schools (1773-1819); 9. Cambridge and Dublin (1790-1820); 10. Tables; Endnotes; Bibliography; Index.

The Impact of Team-Based Learning on Nervous System Examination Knowledge of Nursing Students.

PubMed

Hemmati Maslakpak, Masomeh; Parizad, Naser; Zareie, Farzad

2015-12-01

Team-based learning is one of the active learning approaches in which independent learning is combined with small group discussion in the class. This study aimed to determine the impact of team-based learning in nervous system examination knowledge of nursing students. This quasi-experimental study was conducted on 3(rd) grade nursing students, including 5th semester (intervention group) and 6(th) semester (control group). The traditional lecture method and the team-based learning method were used for educating the examination of the nervous system for intervention and control groups, respectively. The data were collected by a test covering 40-questions (multiple choice, matching, gap-filling and descriptive questions) before and after intervention in both groups. Individual Readiness Assurance Test (RAT) and Group Readiness Assurance Test (GRAT) used to collect data in the intervention group. In the end, the collected data were analyzed by SPSS ver. 13 using descriptive and inferential statistical tests. In team-based learning group, mean and standard deviation was 13.39 (4.52) before the intervention, which had been increased to 31.07 (3.20) after the intervention and this increase was statistically significant. Also, there was a statistically significant difference between the scores of RAT and GRAT in team-based learning group. Using team-based learning approach resulted in much better improvement and stability in the nervous system examination knowledge of nursing students compared to traditional lecture method; therefore, this method could be efficiently used as an effective educational approach in nursing education.

General Motors' R&D: Managing Innovation Globally

NASA Astrophysics Data System (ADS)

Taub, Alan

2006-03-01

The rapid pace of technology development and the globalization of the automobile industry are major forces driving General Motors to devise new ways to innovate faster and more efficiently. In response, GM has developed a global R&D network that has transformed GM's research and development organization from a U.S.-based enterprise to one that is over 30 percent leveraged with collaboration in 16 countries. This talk will focus on the challenges faced as well as the lessons learned and best practices developed in building this network.

An Evidence-Based Approach to Estimating the National and State Costs of PreK-3rd. FCD Policy Brief Advancing PK-3rd. No.10

ERIC Educational Resources Information Center

Picus, Lawrence O.; Odden, Allan; Goetz, Michael

2009-01-01

This study estimates the costs of providing a high-quality PreK-3rd education approach in all 50 states plus the District of Columbia. Relying on an Evidence-Based approach to school finance adequacy, it identifies the staffing resources needed to offer high-quality integrated PreK-3rd programs and then estimates the costs of those resources. By…

Exploratory factor analysis of the Research and Development Culture Index among qualified nurses.

PubMed

Watson, Bill; Clarke, Charlotte; Swallow, Vera; Forster, Stewart

2005-10-01

This paper presents the exploratory factor analysis of a rating instrument for assessing the strength of organizational Research and Development (R&D) culture. Despite nursing's limited research capacity, the discipline is capitalizing upon opportunities to become involved in research and is making strong progress. Within the context of the debate on nursing research capacity, the R&D Culture Index was developed as a means of appraising R&D culture within health care organizations. Factor analysis was carried out on data collected from 485 nursing staff. The method of extraction was Principal Components Analysis with oblique rotation. The Index was developed from the findings of qualitative research conducted with NHS staff. Eighteen items, encompassing the main themes from the data, were initially included in the Index. This pilot instrument was distributed to nursing staff within three different types of NHS Trust. Factor analysis resulted in rejection of two items and the analysis was repeated using the remaining 16 items. Three latent factors were extracted accounting for 58.0% of the variance in the data. The factors were: R&D Support, describing the perceived support within the working environment for R&D activity; Personal R&D Skills and Aptitude, describing an individual's perception of their ability towards R&D activity; and Personal R&D Intention, describing an individual's willingness to engage in R&D activity. Each factor had good internal reliability, as did the overall index. The R&D Culture Index provides an efficient means of assessing the strength of an organization's R&D culture in a way that captures the role of the individual practitioner and the organizational environment. These findings suggest that the continuing promotion of R&D within health care organizations is dependent upon a multi-faceted approach that addresses the learning needs of the organization as well as those of the individual practitioners.

Outcome prediction of third ventriculostomy: a proposed hydrocephalus grading system.

PubMed

Kehler, U; Regelsberger, J; Gliemroth, J; Westphal, M

2006-08-01

An important factor in making a recommendation for different treatment modalities in hydrocephalus patients (VP shunt versus endoscopic third ventriculostomy) is the definition of the underlying pathology which determines the prognosis/outcome of the surgical procedure. Third ventriculostomies (3rd VS) are successful mainly in obstructive hydrocephalus but also in some subtypes of communicating hydrocephalus. A simple, easily applicable grading system that is designed to predict the outcome of 3rd VS is proposed. The hydrocephalus is graded on the basis of the extent of downward bulging of the floor of the third ventricle, which reflects the pressure gradient between the 3rd ventricle and the basal cisterns, presence of directly visualised CSF pathway obstruction in MRI, and the progression of the clinical symptoms resulting in five different grades. In this proposed grading system, grade 1 hydrocephalus subtype shows no downward bulged floor of the 3rd ventricle, no obstruction of the CSF pathway, and no progressive symptoms of hydrocephalus. There is no indication for 3rd VS. Grades 2 to 4 show different combinations of the described parameters. Grade 5 subtype shows a markedly downward bulged floor of the 3rd ventricle and direct detection of the CSF pathway obstruction (i.e., aqueductal stenosis) with progressive clinical deterioration. Retrospective application of this grading scheme to a series of 72 3rd VS has demonstrated a high correlation with the outcome: The success rate in grade 3 reached 40%, in grade 4: 58%, and in grade 5: 95%. This standardised grading system predicts the outcome of 3rd VS and helps in decision making for 3rd VS versus VP shunting.

Characterization of the HLA-DRβ1 third hypervariable region amino acid sequence according to charge and parental inheritance in systemic sclerosis.

PubMed

Gentil, Coline A; Gammill, Hilary S; Luu, Christine T; Mayes, Maureen D; Furst, Dan E; Nelson, J Lee

2017-03-07

Specific HLA class II alleles are associated with systemic sclerosis (SSc) risk, clinical characteristics, and autoantibodies. HLA nomenclature initially developed with antibodies as typing reagents defining DRB1 allele groups. However, alleles from different DRB1 allele groups encode the same third hypervariable region (3rd HVR) sequence, the primary T-cell recognition site, and 3rd HVR charge differences can affect interactions with T cells. We considered 3rd HVR sequences (amino acids 67-74) irrespective of the allele group and analyzed parental inheritance considered according to the 3rd HVR charge, comparing SSc patients with controls. In total, 306 families (121 SSc and 185 controls) were HLA genotyped and parental HLA-haplotype origin was determined. Analysis was conducted according to DRβ1 3rd HVR sequence, charge, and parental inheritance. The distribution of 3rd HVR sequences differed in SSc patients versus controls (p = 0.007), primarily due to an increase of specific DRB1*11 alleles, in accord with previous observations. The 3rd HVR sequences were next analyzed according to charge and parental inheritance. Paternal transmission of DRB1 alleles encoding a +2 charge 3rd HVR was significantly reduced in SSc patients compared with maternal transmission (p = 0.0003, corrected for analysis of four charge categories p = 0.001). To a lesser extent, paternal transmission was increased when charge was 0 (p = 0.021, corrected for multiple comparisons p = 0.084). In contrast, paternal versus maternal inheritance was similar in controls. SSc patients differed from controls when DRB1 alleles were categorized according to 3rd HVR sequences. Skewed parental inheritance was observed in SSc patients but not in controls when the DRβ1 3rd HVR was considered according to charge. These observations suggest that epigenetic modulation of HLA merits investigation in SSc.

Enhanced negative feedback responses in remitted depression.

PubMed

Santesso, Diane L; Steele, Katherine T; Bogdan, Ryan; Holmes, Avram J; Deveney, Christen M; Meites, Tiffany M; Pizzagalli, Diego A

2008-07-02

Major depressive disorder (MDD) is characterized by hypersensitivity to negative feedback that might involve frontocingulate dysfunction. MDD patients exhibit enhanced electrophysiological responses to negative internal (errors) and external (feedback) cues. Whether this dysfunction extends to remitted depressed (RD) individuals with a history of MDD is currently unknown. To address this issue, we examined the feedback-related negativity in RD and control participants using a probabilistic punishment learning task. Despite equivalent behavioral performance, RD participants showed larger feedback-related negativities to negative feedback relative to controls; group differences remained after accounting for residual anxiety and depressive symptoms. The present findings suggest that abnormal responses to negative feedback extend to samples at increased risk for depressive episodes in the absence of current symptoms.

Soft computing prediction of economic growth based in science and technology factors

NASA Astrophysics Data System (ADS)

Marković, Dušan; Petković, Dalibor; Nikolić, Vlastimir; Milovančević, Miloš; Petković, Biljana

2017-01-01

The purpose of this research is to develop and apply the Extreme Learning Machine (ELM) to forecast the gross domestic product (GDP) growth rate. In this study the GDP growth was analyzed based on ten science and technology factors. These factors were: research and development (R&D) expenditure in GDP, scientific and technical journal articles, patent applications for nonresidents, patent applications for residents, trademark applications for nonresidents, trademark applications for residents, total trademark applications, researchers in R&D, technicians in R&D and high-technology exports. The ELM results were compared with genetic programming (GP), artificial neural network (ANN) and fuzzy logic results. Based upon simulation results, it is demonstrated that ELM has better forecasting capability for the GDP growth rate.

Research and Development Productivity in the USSR. Causes of Decline Since the 1960’s and Prospects for the 1980’s

DTIC Science & Technology

1987-03-23

Feminization of R&D personnel ..... .. 210 11.3.2.1 Productivity of women in R&D. 210 11.3.2.2 The share of women in R&D. 212 Chapter 12. Expanding R&D on the...I Changes in the share of women in the higher tiers of scientific hierarchy are of particular importance for judging the impact of feminization ... Feminization must have occurred primarily in higher education, the least important sector of R&D. The share of women among all R&D employees increased

Creative Digital Worksheet Base on Mobile Learning

NASA Astrophysics Data System (ADS)

Wibawa, S. C.; Cholifah, R.; Utami, A. W.; Nurhidayat, A. I.

2018-01-01

The student is required to understand and act in the classroom and it is very important for selecting the media learning to determine the learning outcome. An instructional media is needed to help students achieve the best learning outcome. The objectives of this study are (1) to make Android-based student worksheet, (2) to know the students’ response on Android-based student worksheet in multimedia subject, (3) to determine the student result using Android-based student worksheet. The method used was Research and Development (R&D) using post-test-only in controlled quasi-experimental group design. The subjects of the study were 2 classes, a control class and an experimental class. The results showed (1) Android-based student worksheet was categorized very good as percentage of 85%; (2) the students’ responses was categorized very good as percentage of 86.42%; (3) the experimental class results were better than control class. The average result on cognitive tests on the experimental class was 89.97 and on control class was 78.31; whether the average result on psychomotor test on the experimental class was 89.90 and on the control class was 79.83. In conclusion, student result using Android-based student worksheet was better than those without it.

The influence of survey duration on estimates of food intakes and its relevance for public health nutrition and food safety issues.

PubMed

Lambe, J; Kearney, J; Leclercq, C; Zunft, H F; De Henauw, S; Lamberg-Allardt, C J; Dunne, A; Gibney, M J

2000-02-01

To examine the influence of food consumption survey duration on estimates of percentage consumers, mean total population intakes and intakes among consumers only and to consider its relevance for public health nutrition and food safety issues. Prospective food consumption survey. A multicentre study in five centres in the European Union-Dublin, Ghent, Helsinki, Potsdam and Rome. Teenage subjects were recruited through schools; 948 (80%) out of 1180 subjects completed the survey. 14-day food diaries were used to collect the food consumption data. For mean total population intakes, 53% of the foods had slopes significantly different to 0 (P<0.05). In practical terms (g/day), these differences were small, with 41% of foods having differences of

Genomic Variability of Mycobacterium tuberculosis Strains of the Euro-American Lineage Based on Large Sequence Deletions and 15-Locus MIRU-VNTR Polymorphism

PubMed Central

Rindi, Laura; Medici, Chiara; Bimbi, Nicola; Buzzigoli, Andrea; Lari, Nicoletta; Garzelli, Carlo

2014-01-01

A sample of 260 Mycobacterium tuberculosis strains assigned to the Euro-American family was studied to identify phylogenetically informative genomic regions of difference (RD). Mutually exclusive deletions of regions RD115, RD122, RD174, RD182, RD183, RD193, RD219, RD726 and RD761 were found in 202 strains; the RDRio deletion was detected exclusively among the RD174-deleted strains. Although certain deletions were found more frequently in certain spoligotype families (i.e., deletion RD115 in T and LAM, RD174 in LAM, RD182 in Haarlem, RD219 in T and RD726 in the “Cameroon” family), the RD-defined sublineages did not specifically match with spoligotype-defined families, thus arguing against the use of spoligotyping for establishing exact phylogenetic relationships between strains. Notably, when tested for katG463/gyrA95 polymorphism, all the RD-defined sublineages belonged to Principal Genotypic Group (PGG) 2, except sublineage RD219 exclusively belonging to PGG3; the 58 Euro-American strains with no deletion were of either PGG2 or 3. A representative sample of 197 isolates was then analyzed by standard 15-locus MIRU-VNTR typing, a suitable approach to independently assess genetic relationships among the strains. Analysis of the MIRU-VNTR typing results by using a minimum spanning tree (MST) and a classical dendrogram showed groupings that were largely concordant with those obtained by RD-based analysis. Isolates of a given RD profile show, in addition to closely related MIRU-VNTR profiles, related spoligotype profiles that can serve as a basis for better spoligotype-based classification. PMID:25197794

Third-line therapy in recurrent glioblastoma: is it another chance for bevacizumab?

PubMed

Franceschi, Enrico; Lamberti, Giuseppe; Paccapelo, Alexandro; Di Battista, Monica; Genestreti, Giovenzio; Minichillo, Santino; Mura, Antonella; Bartolini, Stefania; Agati, Raffaele; Brandes, Alba A

2018-04-18

Standard glioblastoma therapy is long-lasting. Among second-line therapy, choices could be bevacizumab and nitrosoureas depending on National Agencies approval. There is no consensus on 3rd line therapy or clinical trials specifically designed for this setting. We reviewed our institutional database on all consecutive patients who received 3rd line therapy for glioblastoma. Data on 168 out of 1337 (12.6%) glioblastoma patients who underwent 3rd line therapy treatment were collected. Third line treatments were bevacizumab or chemotherapy (nitrosourea, temozolomide or carboplatin plus etoposide). Median progression free survival was 2.9 months and median survival time was 6.6 months from the start of 3rd line therapy. Bevacizumab significantly improved progression-free survival (4.7 vs. 2.6 months, p = .020) and survival from 3rd line start (8.0 vs. 6.0 months, p = .014) in respect to chemotherapy. Toxicity of grade ≥ 3 occurred in 13.7% of patients. In multivariate analysis, survival in 3rd line treatment depends on MGMT methylation (p = .006) and treatment with Bevacizumab (p = .011). Third line therapy in selected glioblastoma patients may be feasible and well tolerated. Bevacizumab improved outcome in 3rd line in respect to chemotherapy.

Sematech: Purpose and Performance

PubMed Central

Irwin, Douglas A.; Klenow, Peter J.

1996-01-01

In previous research, we have found a steep learning curve in the production of semiconductors. We estimated that most production knowledge remains internal to the firm, but that a significant fraction “spills over” to other firms. The existence of such spillovers may justify government actions to stimulate research on semiconductor manufacturing technology. The fact that not all production knowledge spills over, meanwhile, creates opportunities for firms to form joint ventures and slide down their learning curves more efficiently. With these considerations in mind, in 1987 14 leading U.S. semiconductor producers, with the assistance of the U.S. government in the form of $100 million in annual subsidies, formed a research and development (R&D) consortium called Sematech. In previous research, we estimated that Sematech has induced its member firms to lower their R&D spending. This may reflect more sharing and less duplication of research, i.e., more research being done with each R&D dollar. If this is the case, then Sematech members may wish to replace any funding withdrawn by the U.S. government. This in turn would imply that the U.S. government’s contributions to Sematech do not induce more semiconductor research than would otherwise occur. PMID:8917487

Promoting interdisciplinary project-based learning to build the skill sets for research and development of medical devices in academia.

PubMed

Krishnan, Shankar

2013-01-01

The worldwide need for rapid expansion and diversification of medical devices and the corresponding requirements in industry pose arduous challenges for educators to train undergraduate biomedical engineering (BME) students. Preparing BME students for working in the research and development (R&D) in medical device industry is not easily accomplished by adopting traditional pedagogical methods. Even with the inclusion of the design and development elements in capstone projects, medical device industry may be still experience a gap in fulfilling their needs in R&D. This paper proposes a new model based on interdisciplinary project-based learning (IDPBL) to address the requirements of building the necessary skill sets in academia for carrying out R&D in medical device industry. The proposed model incorporates IDPBL modules distributed in a stepwise fashion through the four years of a typical BME program. The proposed model involves buy-in and collaboration from faculty as well as students. The implementation of the proposed design in an undergraduate BME program is still in process. However, a variant of the proposed IDPBL method has been attempted at a limited scale at the postgraduate level and has shown some success. Extrapolating the previous results, the adoption of the IDPBL to BME training seems to suggest promising outcomes. Despite numerous implementation challenges, with continued efforts, the proposed IDPBL will be valuable n academia for skill sets building for medical device R&D.

Basic number processing in children with specific learning disorders: Comorbidity of reading and mathematics disorders.

PubMed

Moll, Kristina; Göbel, Silke M; Snowling, Margaret J

2015-01-01

As well as being the hallmark of mathematics disorders, deficits in number processing have also been reported for individuals with reading disorders. The aim of the present study was to investigate separately the components of numerical processing affected in reading and mathematical disorders within the framework of the Triple Code Model. Children with reading disorders (RD), mathematics disorders (MD), comorbid deficits (RD + MD), and typically developing children (TD) were tested on verbal, visual-verbal, and nonverbal number tasks. As expected, children with MD were impaired across a broad range of numerical tasks. In contrast, children with RD were impaired in (visual-)verbal number tasks but showed age-appropriate performance in nonverbal number skills, suggesting their impairments were domain specific and related to their reading difficulties. The comorbid group showed an additive profile of the impairments of the two single-deficit groups. Performance in speeded verbal number tasks was related to rapid automatized naming, a measure of visual-verbal access in the RD but not in the MD group. The results indicate that deficits in number skills are due to different underlying cognitive deficits in children with RD compared to children with MD: a phonological deficit in RD and a deficit in processing numerosities in MD.

A lesson from Japan: research and development efficiency is a key element of pharmaceutical industry consolidation process.

PubMed

Shimura, Hirohisa; Masuda, Sachiko; Kimura, Hiromichi

2014-02-01

Scholarly attention to pharmaceutical companies' ability to sustain research and development (R&D) productivity has increased as they increasingly handle business challenges. Furthermore, the deterioration of R&D productivity has long been considered a major cause of mergers and acquisitions (M&As). This study attempts to investigate quantitatively the possible causes of the deterioration and the relationship between the deterioration and M&As by examining the Japanese pharmaceutical industry. Japan from 1980 to 1997 is an ideal case because of the availability of official data, but more importantly the significant changes in its business environment at the time. Using the Malmquist Index and data envelopment analysis, we measured the deterioration of R&D productivity from 1980 to 1997 based on a sample of 15 Japanese companies. Two lessons can be learned from Japan's case. First, to sustain R&D productivity over the long term, companies should use licensing activities and focus on the dominant therapeutic franchises. Second, if a company fails significantly to catch up with the benchmark, it is likely to pursue an M&A or seek an alternative way to improve R&D productivity. These findings appear similar to the current situation of the global pharmaceutical industry, although Japan pursued more licensing activities than M&A to improve R&D productivity.

The Development of Physics Learning Instrument Based on Hypermedia and Its Influence on the Student Problem Solving Skill

ERIC Educational Resources Information Center

Amin, Bunga Dara; Mahmud, Alimuddin; Muris

2016-01-01

This research aims to produce a learning instrument based on hypermedia which is valid, interesting, practical, and effective as well as to know its influence on the problem based skill of students Mathematical and Science Faculty, Makassar State University. This research is a research and development at (R&D) type. The development procedure…

On JALT96: Crossing Borders. Proceedings of the Annual JALT International Conference on Language Teaching and Learning (23rd, Hiroshima, Japan, November 1996).

ERIC Educational Resources Information Center

Cornwell, Steve, Ed.; Rule, Peggy, Ed.; Sugino, Toshiko, Ed.

Papers from an international conference on language teaching/learning are presented by topic and grouped under seven sections. An introductory section contains two papers on cultural diversity and world English. The second section, on teacher development, contains papers on these topics: teacher development and socialization; teachers' responses…

NPDES Permit for Charlo Wastewater Treatment Facility in Montana

EPA Pesticide Factsheets

Under NPDES permit MT-0022551, the Consolidated Charlo-Lake County Water & Sewer District is authorized to discharge from its wastewater treatment facility located in Lake County, Montana to an unnamed swale that runs to Dublin Gulch.

Davenport, William (1782-1823)

NASA Astrophysics Data System (ADS)

Murdin, P.

2000-11-01

Irish astronomer, born in Dublin, became the second director of the Armagh Observatory. During eight fruitless years of idleness and decline he contributed practically nothing to astronomy until he committed suicide with a shotgun in the study of the observatory....

75 FR 10995 - IFR Altitudes; Miscellaneous Amendments

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-10

... Read in Part Alma, GA VORTAC......... Dublin, GA *3000 VORTAC. *1700--MOCA *2000--GNSS MEA Alma R-345... V626 Is Amended To Read in Part Myton, UT VORTAC Ymont, UT FIX *15000 *12600--MOCA *12600--GNSS MEA...

Descriptive Metadata: Emerging Standards.

ERIC Educational Resources Information Center

Ahronheim, Judith R.

1998-01-01

Discusses metadata, digital resources, cross-disciplinary activity, and standards. Highlights include Standard Generalized Markup Language (SGML); Extensible Markup Language (XML); Dublin Core; Resource Description Framework (RDF); Text Encoding Initiative (TEI); Encoded Archival Description (EAD); art and cultural-heritage metadata initiatives;…

Daedalus in Dublin: A Physicist's Labyrinth

NASA Astrophysics Data System (ADS)

O'Connor, Thomas C.

2014-03-01

I describe some of the rich physical and natural-philosophy heritage of the urban center of the Irish capital Dublin (first tour) and its environs (second tour), in a two-part excursion that could take between two and eight hours in toto. In terms of history, both tours center around the nineteenth century. The first tour is located in and around Trinity College, and we encounter such personages as William Rowan Hamilton, George Fitzgerald, Ernest Walton, and Erwin Schrödinger, among others. Moving away from Trinity College, the second tour explores some of the periphery of the city. I describe the role of politics, money, and religion in shaping the emergence and development of scientific talent among the Irish people, and consequently the footprint left by physics in the city today, with its numerous sites and names that put Irish physics in an honorable place among the nations.

Proceedings of the DoD Information Analysis Center Conference (3rd) Held at Naval Surface Weapons Center, White Oak, Silver Spring, Maryland, 8-9 December 1981,

DTIC Science & Technology

1982-12-09

34 .: .. . .2 .., - " SESSION II Mr. Jerome Persh, Staff Specialist for Materials and qtructures, OUSDR&E Mr. Charles Miller. Program Director for Federal...Control Division, Office of Assistant Secretary of Defense Management Systems Mr. Jerome Pearson, Air Force Flight Dynamics Laboratory Mr. Harry Pebly...your support and I solicit your assistance. The selection of subjects for the Conference is an excellent one; we are all going to learn a lot here. The

A Learning Organization Born in the Crucible of Combat: The 3rd Infantry Brigade, 2nd Division, in World War I

DTIC Science & Technology

2016-06-10

killed in action ( KIA ), with thousands of wounded in action (WIA), in nine months of fighting in Europe.4 However, the ability to overcome these... KIA , WIA, or captured. Of these numbers the 9th Infantry suffered most heavily, losing 44 officers and 1469 enlisted.155 Captain Burress of the 9th...Infantry Brigade reported only eighty-six men KIA , and 285 men WIA.188 The set-piece battle maneuver that was practiced at the division and brigade

Antimicrobial resistance and serotype prevalence of Salmonella isolated from dairy cattle in the southwestern United States.

PubMed

Edrington, T S; Schultz, C L; Bischoff, K M; Callaway, T R; Looper, M L; Genovese, K J; Jung, Y S; McReynolds, J L; Anderson, R C; Nisbet, D J

2004-01-01

Mature dairy cattle were sampled over a 2-year period (2001-2002) on six farms in New Mexico and Texas. Fecal samples (n = 1560) were collected via rectal palpation and cultured for Salmonella, and one isolate from each positive sample was serotyped. Three isolates of each serotype, with the exception of Salmonella Newport (n = 12), were examined for susceptibility to 17 antimicrobial agents. Twenty-two different serotypes were identified from a total of 393 Salmonella isolates. Montevideo was the predominant serotype (27%) followed by Mbandaka (15%), Senftenberg (11.4%), Newport (6.4%), Anatum (4.8%), and Give (4.8%). Salmonella Typhimurium and Dublin, two frequently reported serotypes, accounted for only 1% of the observed serotypes in this study. Sixty-four percent of the serotypes were susceptible to all 17 antimicrobials, 14% were resistant to a single agent, and 22% were multiresistant (2-11 types of resistance). All isolates tested were susceptible to amikacin, apramycin, imipenem, ceftriaxone, nalidixic acid, and ciprofloxacin. The most frequent types of resistance were to sulfamethoxazole, tetracycline, streptomycin, kanamycin, chloramphenicol, and ampicillin (ranging from 8.9 to 22.4%). Serotypes demonstrating multiple resistance included Dublin and Give (resistant to three or more antibiotics), Typhimurium (resistant to five antibiotics), and Newport (four and two isolates resistant to six and nine antibiotics, respectively). Class 1 integrons were present in only two Salmonella Dublin isolates and one Salmonella Newport isolate. The most prevalent resistance patterns observed in this study were toward antimicrobial agents commonly used in cattle, while all Salmonella isolates were susceptible to ceftriaxone and ciprofloxacin, antibiotics used in human medicine.

Mid-Dinantian Waulsortian buildups in the Dublin Basin, Ireland

NASA Astrophysics Data System (ADS)

Somerville, Ian D.; Strogen, Peter; Jones, Gareth Ll.

1992-08-01

The sedimentary history and biostratigraphic setting of Waulsortian carbonate buildups of the Feltrim Limestone Formation (late Courceyan to early Chadian) within the Dublin Basin are described. There is no unique precursor or successor facies to this formation, and the massive Waulsortian banks are composed predominantly of peloidal, skeletal wackestones and lime mudstones with packstones near the tops of banks. These banks form tabular bodies of moderate relief and are interbedded with thin shales and argillaceous crinoidal limestones of inter-bank facies. In the southwest of the basin inter-bank facies are rare and the bank facies have abundant stromatactis cavities, and uniquely at Roselawn a fauna of rugose corals. All buildups in the Dublin Basin have Phase C and/or D component assemblages of Lees and Miller (1985) and are interpreted as accumulating in moderately shallow-water depths, near or within the photic zone. Isopachs for the Feltrim Limestone Formation show a NE-SW-trending axial depocentre where the Waulsortian facies is in excess of 400 m thickness. Deposition appears to have taken place on this "double-sided" ramp, in a manner similar to the model of Lees (1982) for Belgium and southern Britain. Soft-sediment deformation such as large-scale slumping, shale-injections and water-escape structures, not previously recorded from these rocks is widespread. The upper surface of the Feltrim Limestone Formation is fissured and displays a prominent erosion surface. Termination of Waulsortian facies deposition and influx of terrigenous sediment was caused by rapid uplift, attributed to Chadian tectonism. However, eustatic sea-level fall cannot be ruled out as a partial cause of the demise of the Waulsortian.

The prevalence of dental caries and fissure sealants in 12 year old children by disadvantaged status in Dublin (Ireland).

PubMed

Sagheri, D; McLoughlin, J; Clarkson, J J

2009-03-01

The aim was to record dental caries levels and the presence of fissure sealants in 12-year-old schoolchildren whose domestic water supply had been fluoridated since birth in Dublin (Ireland). Cross-sectional study. Participants A representative, random sample of 12-year-old schoolchildren in north-west Dublin. Dental caries levels were recorded using WHO criteria and fissure sealant was recorded when sealant was detectable on a permanent molar tooth. Medical card ownership, as a surrogate for disadvantage, was recorded by use of a questionnaire. Three-hundred and thirty-two (332) children were examined. The mean DMFT was 0.80 (SD 1.24). Analysis (Mann-Whitney U test) based on stratification of the sample according to medical-card status revealed no statistically significant difference between DMFT median scores of children of medical-card holders (i.e., social disadvantage background) and non medical-card holders (p-value = 0.23). However, the data revealed a social gradient in the presence of at least one fissure sealant. Approximately 10% more children in the group of medical-card holders had no fissure sealants present. Fisher's exact test was used to examine the association between the absence of fissure sealants and at least one fissure sealant between the two groups and was considered to be statistically significant (p-value = 0.04). This study demonstrated a social gradient in the presence of fissure sealants, but no such gradient in dental caries levels. This demonstrates the importance of population-based measures in the prevention of dental caries, such as water fluoridation, in reducing oral health inequalities.

[Learning and Repetive Reproduction of Memorized Sequences by the Right and the Left Hand].

PubMed

Bobrova, E V; Lyakhovetskii, V A; Bogacheva, I N

2015-01-01

An important stage of learning a new skill is repetitive reproduction of one and the same sequence of movements, which plays a significant role in forming of the movement stereotypes. Two groups of right-handers repeatedly memorized (6-10 repetitions) the sequences of their hand transitions by experimenter in 6 positions, firstly by the right hand (RH), and then--by the left hand (LH) or vice versa. Random sequences previously unknown to the volunteers were reproduced in the 11 series. Modified sequences were tested in the 2nd and 3rd series, where the same elements' positions were presented in different order. The processes of repetitive sequence reproduction were similar for RH and LH. However, the learning of the modified sequences differed: Information about elements' position disregarding the reproduction order was used only when LH initiated task performing. This information was not used when LH followed RH and when RH performed the task. Consequently, the type of information coding activated by LH helped learn the positions of sequence elements, while the type of information coding activated by RH prevented learning. It is supposedly connected with the predominant role of right hemisphere in the processes of positional coding and motor learning.

How do general practice residents use social networking sites in asynchronous distance learning?

PubMed

Maisonneuve, Hubert; Chambe, Juliette; Lorenzo, Mathieu; Pelaccia, Thierry

2015-09-21

Blended learning environments - involving both face-to-face and remote interactions - make it easier to adapt learning programs to constraints such as residents' location and low teacher-student ratio. Social networking sites (SNS) such as Facebook®, while not originally intended to be used as learning environments, may be adapted for the distance-learning part of training programs. The purpose of our study was to explore the use of SNS for asynchronous distance learning in a blended learning environment as well as its influence on learners' face-to-face interactions. We conducted a qualitative study and carried out semi-structured interviews. We performed purposeful sampling for maximal variation to include eight general practice residents in 2(nd) and 3(rd) year training. A thematic analysis was performed. The social integration of SNS facilitates the engagement of users in their learning tasks. This may also stimulate students' interactions and group cohesion when members meet up in person. Most of the general practice residents who work in the blended learning environment we studied had a positive appraisal on their use of SNS. In particular, we report a positive impact on their engagement in learning and their participation in discussions during face-to-face instruction. Further studies are needed in order to evaluate the effectiveness of SNS in blended learning environments and the appropriation of SNS by teachers.

Modeling Oral Reading Fluency Development in Latino Students: A Longitudinal Study Across Second and Third Grade

PubMed Central

Al Otaiba, Stephanie; Petscher, Yaacov; Williams, Rihana S.; Pappamihiel, N. Eleni; Dyrlund, Allison K.; Connor, Carol

2009-01-01

This study examines growth in oral reading fluency across 2nd and 3rd grade for Latino students grouped in 3 English proficiency levels: students receiving English as a second language (ESL) services (n = 2,182), students exited from ESL services (n = 965), and students never designated as needing services (n = 1,857). An important focus was to learn whether, within these 3 groups, proficiency levels and growth were reliably related to special education status. Using hierarchical linear modeling, the authors compared proficiency levels and growth in oral reading fluency in English between and within groups and then to state reading benchmarks. Findings indicate that oral reading fluency scores reliably distinguished between students with learning disabilities and typically developing students within each group (effect sizes ranging from 0.96 to 1.51). The growth trajectory included a significant quadratic trend (generally slowing over time). These findings support the effectiveness of using oral reading fluency in English to screen and monitor reading progress under Response to Intervention models, but also suggest caution in interpreting oral reading fluency data as part of the process in identifying students with learning disabilities. PMID:25132688

Earthquake: Game-based learning for 21st century STEM education

NASA Astrophysics Data System (ADS)

Perkins, Abigail Christine

To play is to learn. A lack of empirical research within game-based learning literature, however, has hindered educational stakeholders to make informed decisions about game-based learning for 21st century STEM education. In this study, I modified a research and development (R&D) process to create a collaborative-competitive educational board game illuminating elements of earthquake engineering. I oriented instruction- and game-design principles around 21st century science education to adapt the R&D process to develop the educational game, Earthquake. As part of the R&D, I evaluated Earthquake for empirical evidence to support the claim that game-play results in student gains in critical thinking, scientific argumentation, metacognitive abilities, and earthquake engineering content knowledge. I developed Earthquake with the aid of eight focus groups with varying levels of expertise in science education research, teaching, administration, and game-design. After developing a functional prototype, I pilot-tested Earthquake with teacher-participants (n=14) who engaged in semi-structured interviews after their game-play. I analyzed teacher interviews with constant comparison methodology. I used teachers' comments and feedback from content knowledge experts to integrate game modifications, implementing results to improve Earthquake. I added player roles, simplified phrasing on cards, and produced an introductory video. I then administered the modified Earthquake game to two groups of high school student-participants (n = 6), who played twice. To seek evidence documenting support for my knowledge claim, I analyzed videotapes of students' game-play using a game-based learning checklist. My assessment of learning gains revealed increases in all categories of students' performance: critical thinking, metacognition, scientific argumentation, and earthquake engineering content knowledge acquisition. Players in both student-groups improved mostly in critical thinking, having doubled the number of exhibited instances of critical thinking between games. Players in the first group exhibited about a third more instances of metacognition between games, while players in the second group doubled such instances. Between games, players in both groups more than doubled the number of exhibited instances of using earthquake engineering content knowledge. The student-players expanded use of scientific argumentation for all game-based learning checklist categories. With empirical evidence, I conclude play and learning can connect for successful 21 st century STEM education.

ADDIE Model Application Promoting Interactive Multimedia

NASA Astrophysics Data System (ADS)

Baharuddin, B.

2018-02-01

This paper presents the benefits of interactive learning in a vocational high school, which is developed by Research and Developmet (R&D) method. The questionnaires, documentations, and instrument tests are used to obtain data and it is analyzed by descriptive statistic. The results show the students’ competence is generated up to 80.00 %, and the subject matter aspects of the content is up to 90.00 %. The learning outcomes average is 85. This type media fulfils the proposed objective which can enhance the learning outcome.

Learning a Procedure from Multimedia Instructions: The Effects of Film and Practice.

DTIC Science & Technology

1983-11-01

retaining information in the visuals and verbals of an educational movie. Educational Communication and Technology Journal, 31, 23-32, 1983. Baggett...ADA136 658 LEARNING 4 ROCEDUE FROM MULTMEDIA INSTRUCTIONS:R EFFE U F FIM AN U RD N A BUS E S U C AN , S ENE RA DO NUU8 CS R BOULD R OFCGIIVNCEC...INSTITUTE OF COGNITIVE S CIENCE Learning a Procedure from Multimedia Instructions: Iwo* The Effects of Film and Practice Deprtment of psyhology

Remediation System Evaluation, Former Honeywell Facility in Fort Washington, Pennsylvania

EPA Pesticide Factsheets

The Honeywell facility is located at 1100 Virginia Drive in Upper Dublin Township, Montgomery County, Pennsylvania in the Fort Washington Industrial Park. The property is approximately 67 acres and is owned by 1100 Virginia Drive Associates.

Environmental impact case study : Project 0100-077-105, C-501 : Dublin, Virginia.

DOT National Transportation Integrated Search

1971-01-01

At the request of the Environmental Quality Division of the Virginia Department of Highways, the Environmental and Economics Section of the Virginia Highway Research Council conducted a study to determine the probable socioeconomic and environmental ...

Gynecologic simulation training increases medical student confidence and interest in women's health.

PubMed

Nitschmann, Caroline; Bartz, Deborah; Johnson, Natasha R

2014-01-01

Exposure to commonly performed gynecologic procedures via simulation has potential to improve medical student knowledge and foster confidence with procedures. To implement and evaluate a gynecologic simulation curriculum for 3rd-year medical students during their obstetrics and gynecology core clerkship. A gynecologic simulation curriculum was implemented for medical students during their obstetrics and gynecology clerkship. Participants completed pre-and postsurveys to assess learner confidence; effect on interest in a surgical field, women's health, and obstetrics and gynecology as a career; and whether the session met their learning needs. Fifty-nine students participated. Improved confidence in performing the procedures was noted when comparing mean survey scores before and after the simulation for IUD insertion and removal (1.9 pre, 4.3 post, p < .0001), for dilatation and curettage (1.7 pre, 3.8 post, p < .0001), and basic laparoscopy skills (2.1 pre, 4.3 post, p < .0001). An increase in pursuing a surgical field (3.3 pre, 3.6 post, p < .003) and interest in women's health (3.7 pre, 4.9 post, p < .004) was noted among students after the simulation session. The curriculum strongly met the students learning needs with a mean score of 4.54 on the 5-point scale. Gynecologic simulation training for medical students can increase confidence in procedures, interest in pursuing a surgical field and women's health, and was highly effective in meeting student learning needs.

Targeted intervention strategies to optimise diversion of BMW in the Dublin, Ireland region

DOE Office of Scientific and Technical Information (OSTI.GOV)

Purcell, M., E-mail: mary.purcell@cit.ie; Centre for Water Resources Research, School of Architecture, Landscape and Civil Engineering, University College Dublin, Newstead, Belfield, Dublin 4; Magette, W.L.

Highlights: > Previous research indicates that targeted strategies designed for specific areas should lead to improved diversion. > Survey responses and GIS model predictions from previous research were the basis for goal setting. > Then logic modelling and behavioural research were employed to develop site-specific management intervention strategies. > Waste management initiatives can be tailored to specific needs of areas rather than one size fits all means currently used. - Abstract: Urgent transformation is required in Ireland to divert biodegradable municipal waste (BMW) from landfill and prevent increases in overall waste generation. When BMW is optimally managed, it becomes amore » resource with value instead of an unwanted by-product requiring disposal. An analysis of survey responses from commercial and residential sectors for the Dublin region in previous research by the authors proved that attitudes towards and behaviour regarding municipal solid waste is spatially variable. This finding indicates that targeted intervention strategies designed for specific geographic areas should lead to improved diversion rates of BMW from landfill, a requirement of the Landfill Directive 1999/31/EC. In the research described in this paper, survey responses and GIS model predictions from previous research were the basis for goal setting, after which logic modelling and behavioural research were employed to develop site-specific waste management intervention strategies. The main strategies devised include (a) roll out of the Brown Bin (Organics) Collection and Community Workshops in Dun Laoghaire Rathdown, (b) initiation of a Community Composting Project in Dublin City (c) implementation of a Waste Promotion and Motivation Scheme in South Dublin (d) development and distribution of a Waste Booklet to promote waste reduction activities in Fingal (e) region wide distribution of a Waste Booklet to the commercial sector and (f) Greening Irish Pubs Initiative. Each of these strategies was devised after interviews with both the residential and commercial sectors to help make optimal waste management the norm for both sectors. Strategy (b), (e) and (f) are detailed in this paper. By integrating a human element into accepted waste management approaches, these strategies will make optimal waste behaviour easier to achieve. Ultimately this will help divert waste from landfill and improve waste management practice as a whole for the region. This method of devising targeted intervention strategies can be adapted for many other regions.« less

78 FR 26616 - Draft NOAA Five Year Research and Development Plan

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-07

... understanding among NOAA's leadership, workforce, partners, constituents, and Congress on how the agency's R&D... learn from its experiences. ADDRESSES: The draft can be found at http://nrc.noaa.gov/CouncilProducts...

78 FR 59080 - Audit and Financial Management Advisory Committee (AFMAC)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-25

... Administration, 409 3rd Street SW., Office of the Chief Financial Officer Conference Room, 6th Floor, Washington.... Jonathan Carver, Chief Financial Officer, 409 3rd Street SW., 6th Floor, Washington, DC 20416, phone: (202...-1608, email: [email protected] ; SBA, Office of Chief Financial Officer, 409 3rd Street SW...

How do early emotional experiences in the operating theatre influence medical student learning in this environment?

PubMed

Bowrey, David J; Kidd, Jane M

2014-01-01

The emotions experienced by medical students on first exposure to the operating theatre are unknown. It is also unclear what influence these emotions have on the learning process. To understand the emotions experienced by students when in the operating theatre for the first time and the impact of these emotions on learning. Nine 3rd-year medical students participated in semistructured interviews to explore these themes. A qualitative approach was used; interviews were transcribed and coded thematically. All participants reported initial negative emotions (apprehension, anxiety, fear, shame, overwhelmed), with excitement being reported by 3. Six participants considered that their anxiety was so overwhelming that it was detrimental to their learning. Participants described a period of familiarization to the environment, after which learning was facilitated. Early learning experiences centered around adjustment to the physical environment of the operating theatre. Factors driving initial negative feelings were loss of familiarity, organizational issues, concerns about violating protocol, and a fear of syncope. Participants considered that it took a median of 1 week (range = 1 day-3 weeks) or 5 visits to the operating theatre (range = 1-10) before feeling comfortable in the new setting. Emotions experienced on subsequent visits to the operating theatre were predominantly positive (enjoyment, happiness, confident, involved, pride). Two participants reported negative feelings related to social exclusion. Being included in the team was a powerful determinant of enjoyment. These findings indicate that for learning in the operating theatre to be effective, addressing the negative emotions of the students might be beneficial. This could be achieved by a formal orientation program for both learners and tutors in advance of attendance in the operating theatre. For learning to be optimized, students must feel a sense of inclusion in the theatre community of practice.

Interfering effects of retrieval in learning new information.

PubMed

Finn, Bridgid; Roediger, Henry L

2013-11-01

In 7 experiments, we explored the role of retrieval in associative updating, that is, in incorporating new information into an associative memory. We tested the hypothesis that retrieval would facilitate incorporating a new contextual detail into a learned association. Participants learned 3 pieces of information-a person's face, name, and profession (in Experiments 1-5). In the 1st phase, participants in all conditions learned faces and names. In the 2nd phase, participants either restudied the face-name pair (the restudy condition) or were given the face and asked to retrieve the name (the test condition). In the 3rd phase, professions were presented for study just after restudy or testing. Our prediction was that the new information (the profession) would be more readily learned following retrieval of the face-name association compared to restudy of the face-name association. However, we found that the act of retrieval generally undermined acquisition of new associations rather than facilitating them. This detrimental effect emerged on both immediate and delayed tests. Further, the effect was not due to selective attention to feedback because we found impairment whether or not feedback was provided after the Phase 2 test. The data are novel in showing that the act of retrieving information can inhibit the ability to learn new information shortly thereafter. The results are difficult to accommodate within current theories that mostly emphasize benefits of retrieval for learning. PsycINFO Database Record (c) 2013 APA, all rights reserved.

Chunking and Consolidation: A Theoretical Synthesis of Semantic Networks, Configuring in Conditioning, S--R Versus Cognitive Learning, Normal Forgetting, the Amnesic Syndrome, and the Hippocampal Arousal System.

ERIC Educational Resources Information Center

Wickelgren, Wayne A.

1979-01-01

The relationship between current information processing and prior associative theories of human and animal learning, memory, and amnesia are discussed. The paper focuses on the two components of the amnesic syndrome, retrograde amnesia and anterograde amnesia. A neural theory of chunking and consolidation is proposed. (Author/RD)

Workshop Proceedings for USAF Institute for National Security Studies: Combatting Fissile Materials Smuggling Workshop #5, Held in Dublin, California, 3-4 February 1998.

DTIC Science & Technology

1999-02-01

civil defense program. Responsibility is spread over lots of government agencies. E. Nadler: The media has hyped nuclear smuggling efforts, which did...help to deter criminals, but the media doesn’t pay much attention yet to BW. It has been the focus of attention recently in Iraq. J. Adams: The BW issue...view it. The issue is that the balance is off center. A. Weber: I agree that the balance is off on the policy side. But BW is getting media attention

R&D 100 Awards | NREL

Science.gov Websites

a cost of about $.50/watt. Learn more HP Apollo 8000 System HP Apollo 8000 System Uses component Award - HP Apollo 8000 System - Steve Hammond and Team 2008 Editor's Choice Award - Hybrid CIGS (copper

Prospective Evaluation of Prior Image Constrained Compressed Sensing (PICCS) Algorithm in Abdominal CT: A comparison of reduced dose with standard dose imaging

PubMed Central

Lubner, Meghan G.; Pickhardt, Perry J.; Kim, David H.; Tang, Jie; Munoz del Rio, Alejandro; Chen, Guang-Hong

2014-01-01

Purpose To prospectively study CT dose reduction using the “prior image constrained compressed sensing” (PICCS) reconstruction technique. Methods Immediately following routine standard dose (SD) abdominal MDCT, 50 patients (mean age, 57.7 years; mean BMI, 28.8) underwent a second reduced-dose (RD) scan (targeted dose reduction, 70-90%). DLP, CTDIvol and SSDE were compared. Several reconstruction algorithms (FBP, ASIR, and PICCS) were applied to the RD series. SD images with FBP served as reference standard. Two blinded readers evaluated each series for subjective image quality and focal lesion detection. Results Mean DLP, CTDIvol, and SSDE for RD series was 140.3 mGy*cm (median 79.4), 3.7 mGy (median 1.8), and 4.2 mGy (median 2.3) compared with 493.7 mGy*cm (median 345.8), 12.9 mGy (median 7.9 mGy) and 14.6 mGy (median 10.1) for SD series, respectively. Mean effective patient diameter was 30.1 cm (median 30), which translates to a mean SSDE reduction of 72% (p<0.001). RD-PICCS image quality score was 2.8±0.5, improved over the RD-FBP (1.7±0.7) and RD-ASIR(1.9±0.8)(p<0.001), but lower than SD (3.5±0.5)(p<0.001). Readers detected 81% (184/228) of focal lesions on RD-PICCS series, versus 67% (153/228) and 65% (149/228) for RD-FBP and RD-ASIR, respectively. Mean image noise was significantly reduced on RD-PICCS series (13.9 HU) compared with RD-FBP (57.2) and RD-ASIR (44.1) (p<0.001). Conclusion PICCS allows for marked dose reduction at abdominal CT with improved image quality and diagnostic performance over reduced-dose FBP and ASIR. Further study is needed to determine indication-specific dose reduction levels that preserve acceptable diagnostic accuracy relative to higher-dose protocols. PMID:24943136

A role of decision-making competency in science learning utilizing a social valuation framework

NASA Astrophysics Data System (ADS)

Katsuo, Akihito

2005-11-01

The role of decision-making in learning performance has been an occasional topic in the research literature in science education, but rarely has it been a central issue in the field. Nonetheless, recent studies regarding the topic in several fields other than education, such as cognitive neuroscience and social choice theory, indicate the fundamental importance(s) of the topic. This study focuses on a possible role of decision-making in science learning. Initially the study was designed to probe the decision-making ability of elementary school children with a modified version of the Iowa Gambling Task (IGT). The experiment involved six Montessori 3rd and 4th grade students as the experimental group and eight public school 3rd and 4th grade students as the control group. The result of the modified IGT revealed a tendency in choice trajectories favoring children at the Montessori school. However, the probabilistic value went below the statistically significant level set by the U test. A further study focused on the impact of better decision-making ability revealed in the first experiment on performances with a science learning module that emphasized collective reasoning. The instruction was based on a set of worksheets with multiple choices on which students were asked to make predictions with and to provide supportive arguments regarding outcomes of experiments introduced in the worksheet. Then the whole class was involved with a real experiment to see which choice was correct. The findings in the study indicated that the Montessori students often obtained higher scores than non-Montessori students in making decision with a tendency of consistency in terms of their choices of the alternatives on the worksheets. The findings of the experiments were supported by a correlational analysis that was performed at the end of study. Although no statistically significant correlations were found, there was a tendency for positively associative shifts between the scores of the modified IGT and the scores for the performances on the science module for the Montessori students.

Utilization of Concurrent Buffers to Facilitate Seamless Data Transition in Tactical Cellular Communications

DTIC Science & Technology

2015-09-01

INTENTIONALLY LEFT BLANK xiii LIST OF ACRONYMS AND ABBREVIATIONS 2G 2nd Generation 3G 3rd Generation 3GPP 3rd Generation Partnership Project 4G 4th...System (UMTS) is the standard that governs 3rd Generation ( 3G ) migration of Global Services for Mobile (GSM) networks. It defines packet-based...network may assist or mitigate. 14. SUBJECT TERMS IEEE, 802.21, Media Independent Handover, mobile , communications, cyber, tactical, buffer, cellular

Guidelines for incorporating scientific knowledge and practice on rare diseases into higher education: neuronal ceroid lipofuscinoses as a model disorder.

PubMed

Cismondi, Inés Adriana; Kohan, Romina; Adams, Heather; Bond, Mike; Brown, Rachel; Cooper, Jonathan D; de Hidalgo, Perla K; Holthaus, Sophia-Martha Kleine; Mole, Sara E; Mugnaini, Julia; de Ramirez, Ana María Oller; Pesaola, Favio; Rautenberg, Gisela; Platt, Frances M; Noher de Halac, Inés

2015-10-01

This article addresses the educational issues associated with rare diseases (RD) and in particular the Neuronal Ceroid Lipofuscinoses (NCLs, or CLN diseases) in the curricula of Health Sciences and Professional's Training Programs. Our aim is to develop guidelines for improving scientific knowledge and practice in higher education and continuous learning programs. Rare diseases (RD) are collectively common in the general population with 1 in 17 people affected by a RD in their lifetime. Inherited defects in genes involved in metabolism are the commonest group of RD with over 8000 known inborn errors of metabolism. The majority of these diseases are neurodegenerative including the NCLs. Any professional training program on NCL must take into account the medical, social and economic burdens related to RDs. To address these challenges and find solutions to them it is necessary that individuals in the government and administrative authorities, academia, teaching hospitals and medical schools, the pharmaceutical industry, investment community and patient advocacy groups all work together to achieve these goals. The logistical issues of including RD lectures in university curricula and in continuing medical education should reflect its complex nature. To evaluate the state of education in the RD field, a summary should be periodically up dated in order to assess the progress achieved in each country that signed up to the international conventions addressing RD issues in society. It is anticipated that auditing current practice will lead to higher standards and provide a framework for those educators involved in establishing RD teaching programs world-wide. Copyright © 2015 Elsevier B.V. All rights reserved.

Final analysis of survival outcomes in the phase 3 FIRST trial of up-front treatment for multiple myeloma.

PubMed

Facon, Thierry; Dimopoulos, Meletios A; Dispenzieri, Angela; Catalano, John V; Belch, Andrew; Cavo, Michele; Pinto, Antonello; Weisel, Katja; Ludwig, Heinz; Bahlis, Nizar J; Banos, Anne; Tiab, Mourad; Delforge, Michel; Cavenagh, Jamie D; Geraldes, Catarina; Lee, Je-Jung; Chen, Christine; Oriol, Albert; De La Rubia, Javier; White, Darrell; Binder, Daniel; Lu, Jin; Anderson, Kenneth C; Moreau, Philippe; Attal, Michel; Perrot, Aurore; Arnulf, Bertrand; Qiu, Lugui; Roussel, Murielle; Boyle, Eileen; Manier, Salomon; Mohty, Mohamad; Avet-Loiseau, Herve; Leleu, Xavier; Ervin-Haynes, Annette; Chen, Guang; Houck, Vanessa; Benboubker, Lotfi; Hulin, Cyrille

2018-01-18

This FIRST trial final analysis examined survival outcomes in patients with transplant-ineligible newly diagnosed multiple myeloma (NDMM) treated with lenalidomide and low-dose dexamethasone until disease progression (Rd continuous), Rd for 72 weeks (18 cycles; Rd18), or melphalan, prednisone, and thalidomide (MPT; 72 weeks). The primary endpoint was progression-free survival (PFS; primary comparison: Rd continuous vs MPT). Overall survival (OS) was a key secondary endpoint (final analysis prespecified ≥60 months' follow-up). Patients were randomized to Rd continuous (n = 535), Rd18 (n = 541), or MPT (n = 547). At a median follow-up of 67 months, PFS was significantly longer with Rd continuous vs MPT (hazard ratio [HR], 0.69; 95% confidence interval [CI], 0.59-0.79; P < .00001) and was similarly extended vs Rd18. Median OS was 10 months longer with Rd continuous vs MPT (59.1 vs 49.1 months; HR, 0.78; 95% CI, 0.67-0.92; P = .0023), and similar with Rd18 (62.3 months). In patients achieving complete or very good partial responses, Rd continuous had an ≈30-month longer median time to next treatment vs Rd18 (69.5 vs 39.9 months). Over half of all patients who received second-line treatment were given a bortezomib-based therapy. Second-line outcomes were improved in patients receiving bortezomib after Rd continuous and Rd18 vs after MPT. No new safety concerns, including risk for secondary malignancies, were observed. Treatment with Rd continuous significantly improved survival outcomes vs MPT, supporting Rd continuous as a standard of care for patients with transplant-ineligible NDMM. This trial was registered at www.clinicaltrials.gov as #NCT00689936 and EudraCT as 2007-004823-39. © 2018 by The American Society of Hematology.

Final analysis of survival outcomes in the phase 3 FIRST trial of up-front treatment for multiple myeloma

PubMed Central

Dimopoulos, Meletios A.; Dispenzieri, Angela; Catalano, John V.; Belch, Andrew; Cavo, Michele; Pinto, Antonello; Weisel, Katja; Ludwig, Heinz; Bahlis, Nizar J.; Banos, Anne; Tiab, Mourad; Delforge, Michel; Cavenagh, Jamie D.; Geraldes, Catarina; Lee, Je-Jung; Chen, Christine; Oriol, Albert; De La Rubia, Javier; White, Darrell; Binder, Daniel; Lu, Jin; Anderson, Kenneth C.; Moreau, Philippe; Attal, Michel; Perrot, Aurore; Arnulf, Bertrand; Qiu, Lugui; Roussel, Murielle; Boyle, Eileen; Manier, Salomon; Mohty, Mohamad; Avet-Loiseau, Herve; Leleu, Xavier; Ervin-Haynes, Annette; Chen, Guang; Houck, Vanessa; Benboubker, Lotfi; Hulin, Cyrille

2018-01-01

This FIRST trial final analysis examined survival outcomes in patients with transplant-ineligible newly diagnosed multiple myeloma (NDMM) treated with lenalidomide and low-dose dexamethasone until disease progression (Rd continuous), Rd for 72 weeks (18 cycles; Rd18), or melphalan, prednisone, and thalidomide (MPT; 72 weeks). The primary endpoint was progression-free survival (PFS; primary comparison: Rd continuous vs MPT). Overall survival (OS) was a key secondary endpoint (final analysis prespecified ≥60 months’ follow-up). Patients were randomized to Rd continuous (n = 535), Rd18 (n = 541), or MPT (n = 547). At a median follow-up of 67 months, PFS was significantly longer with Rd continuous vs MPT (hazard ratio [HR], 0.69; 95% confidence interval [CI], 0.59-0.79; P < .00001) and was similarly extended vs Rd18. Median OS was 10 months longer with Rd continuous vs MPT (59.1 vs 49.1 months; HR, 0.78; 95% CI, 0.67-0.92; P = .0023), and similar with Rd18 (62.3 months). In patients achieving complete or very good partial responses, Rd continuous had an ≈30-month longer median time to next treatment vs Rd18 (69.5 vs 39.9 months). Over half of all patients who received second-line treatment were given a bortezomib-based therapy. Second-line outcomes were improved in patients receiving bortezomib after Rd continuous and Rd18 vs after MPT. No new safety concerns, including risk for secondary malignancies, were observed. Treatment with Rd continuous significantly improved survival outcomes vs MPT, supporting Rd continuous as a standard of care for patients with transplant-ineligible NDMM. This trial was registered at www.clinicaltrials.gov as #NCT00689936 and EudraCT as 2007-004823-39. PMID:29150421

[Development and effect analysis of web-based instruction program to prevent elementary school students from safety accidents].

PubMed

Chung, Eun-Soon; Jeong, Ihn-Sook; Song, Mi-Gyoung

2004-06-01

This study was aimed to develop a WBI(Web Based Instruction) program on safety for 3rd grade elementary school students and to test the effects of it. The WBI program was developed using Macromedia flash MX, Adobe Illustrator 10.0 and Adobe Photoshop 7.0. The web site was http://www.safeschool.co.kr. The effect of it was tested from Mar 24, to Apr 30, 2003. The subjects were 144 students enrolled in the 3rd grade of an elementary school in Gyungju. The experimental group received the WBI program lessons while each control group received textbook-based lessons with visual presenters and maps, 3 times. Data was analyzed with descriptive statistics, and chi2 test, t-test, and repeated measure ANOVA. First, the WBI group reported a longer effect on knowledge and practice of accident prevention than the textbook-based lessons, indicating that the WBI is more effective. Second, the WBI group was better motivated to learn the accident prevention lessons, showing that the WBI is effective. As a result, the WBI group had total longer effects on knowledge, practice and motivation of accident prevention than the textbook-based instruction. We recommend that this WBI program be used in each class to provide more effective safety instruction in elementary schools.

76 FR 38613 - Initiation of Five-Year (“Sunset”) Review

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-01

.... Alloy Steel Pipe (3rd Review). A-580-809 731-TA-533 South Korea Circular Welded Non- David Goldberger, (202) 482-4136. Alloy Steel Pipe (3rd Review). A-489-501 731-TA-273 Turkey Welded Carbon Steel David Goldberger, (202) 482-4136. Pipe & Tube (3rd Review). C-489-502 701-TA-253 Turkey Welded Carbon Steel David...

Foundational Skills to Support Reading for Understanding in Kindergarten through 3rd Grade. Educator's Practice Guide. NCEE 2016-4008

ERIC Educational Resources Information Center

Foorman, Barbara; Beyler, Nicholas; Borradaile, Kelley; Coyne, Michael; Denton, Carolyn A.; Dimino, Joseph; Furgeson, Joshua; Hayes, Lynda; Henke, Juliette; Justice, Laura; Keating, Betsy; Lewis, Warnick; Sattar, Samina; Streke, Andrei; Wagner, Richard; Wissel, Sarah

2016-01-01

The goal of this practice guide is to offer educators specific, evidence-based recommendations for teaching foundational reading skills to students in kindergarten through 3rd grade. This guide is a companion to the existing practice guide, "Improving Reading Comprehension in Kindergarten Through 3rd Grade", and as a set, these guides…

Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program

PubMed Central

Hamey, Fiona K.; Errami, Youssef

2017-01-01

Differentiation of lineage-committed cells from multipotent progenitors requires the establishment of accessible chromatin at lineage-specific transcriptional enhancers and promoters, which is mediated by pioneer transcription factors that recruit activating chromatin remodeling complexes. Here we show that the Mbd3/nucleosome remodeling and deacetylation (NuRD) chromatin remodeling complex opposes this transcriptional pioneering during B cell programming of multipotent lymphoid progenitors by restricting chromatin accessibility at B cell enhancers and promoters. Mbd3/NuRD-deficient lymphoid progenitors therefore prematurely activate a B cell transcriptional program and are biased toward overproduction of pro–B cells at the expense of T cell progenitors. The striking reduction in early thymic T cell progenitors results in compensatory hyperproliferation of immature thymocytes and development of T cell lymphoma. Our results reveal that Mbd3/NuRD can regulate multilineage differentiation by constraining the activation of dormant lineage-specific enhancers and promoters. In this way, Mbd3/NuRD protects the multipotency of lymphoid progenitors, preventing B cell–programming transcription factors from prematurely enacting lineage commitment. Mbd3/NuRD therefore controls the fate of lymphoid progenitors, ensuring appropriate production of lineage-committed progeny and suppressing tumor formation. PMID:28899870

Development of stable isotope mixing models in ecology - Dublin

EPA Science Inventory

More than 40 years ago, stable isotope analysis methods used in geochemistry began to be applied to ecological studies. One common application is using mathematical mixing models to sort out the proportional contributions of various sources to a mixture. Examples include contri...

Monopoly Profits: The Market for Taxi Licenses.

ERIC Educational Resources Information Center

Keane, Michael

1981-01-01

Presents a case study dealing with open versus closed markets for use in college economics classes. Using the example of the taxi license monopoly in Dublin, Ireland, students examine how theories of supply and demand explain the characteristics of open and closed markets. (AM)

Cataloging the Net: Can We Do It?

ERIC Educational Resources Information Center

Oder, Norman

1998-01-01

Discusses possibilities for cataloging Internet resources and the role that the library profession can play. Topics include the Dublin Core metadata; public library projects (Michigan Electronic Library "MEL" and Librarians' Index to the Internet "LII"); academic library projects (INFOMINE, Scout Report); commercial sites…

Influence of passive smoking on learning in elementary school.

PubMed

Jorge, Juliana Gomes; Botelho, Clóvis; Silva, Ageo Mário Cândido; Moi, Gisele Pedroso

2016-01-01

To analyze the association between household smoking and the development of learning in elementary schoolchildren. Cross-sectional study with 785 students from the 2nd to the 5th year of elementary school. Students were evaluated by the School Literacy Screening Protocol to identify the presence of learning disabilities. Mothers/guardians were interviewed at home through a validated questionnaire. Descriptive and bivariate analysis, as well as multivariate Poisson regression, were performed. In the final model, the variables associated with learning difficulties were current smoking at the household in the presence of the child (PR=6.10, 95% CI: 4.56 to 8.16), maternal passive smoking during pregnancy (PR=1.46, 95% CI: 1.07 to 2.01), students attending the 2nd and 3rd years of Elementary School (PR=1.44, 95% CI: 1.10 to 1.90), and being children of mothers with only elementary level education (PR=1.36, 95% CI: 1.04 to 1.79). The study demonstrated an association between passive exposure to tobacco smoke and learning difficulties at school. Copyright © 2016 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

Reciprocal benefit to senior and junior peers: An outcome of a pilot research workshop at medical university.

PubMed

Ahsin, Sadia; Abbas, Seyyeda; Zaidi, Noshin; Azad, Nadia; Kaleem, Fatima

2015-08-01

A study was planned to explore and evaluate the role of senior peers in the learning process of their juniors during a Research Methodology workshop, and to assess educational advantages for seniors in leading roles. Twenty medical students participated with 15 juniors (1st to 3rd year) and 5 seniors (final/fourth year) divided into 5 groups with one senior student each at Foundation University Medical College, Islamabad, Pakistan. The seniors supervised and engaged the groups to develop research questions, formulate objectives, review literature, outline study designs, develop study tools/questionnaire and finally shape their projects in synopsis. Overall advantages to both juniors and seniors through this peer-assisted learning model were assessed by feedback proformas with open and closed-ended questions. Senior peers' facilitation was effective in the learning process of junior peers. Senior peers also gained academic benefit by exercising their leadership qualities through teaching and maintaining group dynamics.

A Big Data Platform for Storing, Accessing, Mining and Learning Geospatial Data

NASA Astrophysics Data System (ADS)

Yang, C. P.; Bambacus, M.; Duffy, D.; Little, M. M.

2017-12-01

Big Data is becoming a norm in geoscience domains. A platform that is capable to effiently manage, access, analyze, mine, and learn the big data for new information and knowledge is desired. This paper introduces our latest effort on developing such a platform based on our past years' experiences on cloud and high performance computing, analyzing big data, comparing big data containers, and mining big geospatial data for new information. The platform includes four layers: a) the bottom layer includes a computing infrastructure with proper network, computer, and storage systems; b) the 2nd layer is a cloud computing layer based on virtualization to provide on demand computing services for upper layers; c) the 3rd layer is big data containers that are customized for dealing with different types of data and functionalities; d) the 4th layer is a big data presentation layer that supports the effient management, access, analyses, mining and learning of big geospatial data.

Large Sequence Polymorphisms of the Euro-American lineage of Mycobacterium tuberculosis: a phylogenetic reconstruction and evidence for convergent evolution in the DR locus.

PubMed

Rindi, Laura; Lari, Nicoletta; Garzelli, Carlo

2012-10-01

The Euro-American lineage of the Mycobacterium tuberculosis complex consists of 10 sublineages, each defined by a deletion of a large genomic region (RD, region of difference); by spoligotyping, that probes the polymorphism of the Direct Repeat (DR) locus, the Euro-American strains are classified into 5 lineages (T, Haarlem, LAM, S and X) and 34 sublineages, but the relationships between the RD-defined sublineages and the spoligotype groupings are largely unclear. By testing a global sample of 158 Euro-American strains, mutually exclusive deletions of RD115, RD122, RD174, RD182, RD183, RD193, RD219, RD726 or RD761 were found in 122 strains; deletion of RD724, typical of strains from Central Africa, was not found. The RD-defined sublineages, tested for katG463/gyrA95 polymorphism, belonged to Principal Genotypic Group (PGG) 2, with the exception of RD219 sublineage belonging to PGG3; the 36 strains with no deletion were of either PGG2 or 3. Based on these polymorphisms, a phylogenetic reconstruction of the Euro-American lineage, that integrates the previously reported phylogeny, is proposed. Although certain deletions were found to be associated to certain spoligotype lineages (i.e., deletion RD115 to T and LAM, RD174 to LAM, RD182 to Haarlem, RD219 to T), our analysis indicates a general lack of concordance between RD-defined sublineages and spoligotype groupings. Moreover, of the 42 spoligotypes detected among the study strains, sixteen were shared by strains belonging to different RD sublineages. IS6110-RFLP analysis of strains sharing spoligotypes confirmed a poor genetic relatedness between strains of different RD sublineages. These findings provide evidence for the occurrence of a high degree of homoplasy in the DR locus leading to convergent evolution to identical spoligotypes. The incongruence between Large Sequence Polymorphism and spoligotype polymorphism argues against the use of spoligotyping for establishing phylogenetic relationships within the Euro-American lineage. Copyright © 2012 Elsevier B.V. All rights reserved.

10 CFR 1045.4 - Responsibilities.

Code of Federal Regulations, 2013 CFR

2013-01-01

... declassification of RD and FRD in accordance with the Atomic Energy Act; (2) In coordination with the DoD, develop regulations to implement the RD and FRD classification system; (3) Determine whether nuclear-related information is RD; (4) Oversee agency implementation of the RD and FRD classification system to ensure...

10 CFR 1045.4 - Responsibilities.

Code of Federal Regulations, 2014 CFR

2014-01-01

... declassification of RD and FRD in accordance with the Atomic Energy Act; (2) In coordination with the DoD, develop regulations to implement the RD and FRD classification system; (3) Determine whether nuclear-related information is RD; (4) Oversee agency implementation of the RD and FRD classification system to ensure...

10 CFR 1045.4 - Responsibilities.

Code of Federal Regulations, 2011 CFR

2011-01-01

... declassification of RD and FRD in accordance with the Atomic Energy Act; (2) In coordination with the DoD, develop regulations to implement the RD and FRD classification system; (3) Determine whether nuclear-related information is RD; (4) Oversee agency implementation of the RD and FRD classification system to ensure...

10 CFR 1045.4 - Responsibilities.

Code of Federal Regulations, 2012 CFR

2012-01-01

... declassification of RD and FRD in accordance with the Atomic Energy Act; (2) In coordination with the DoD, develop regulations to implement the RD and FRD classification system; (3) Determine whether nuclear-related information is RD; (4) Oversee agency implementation of the RD and FRD classification system to ensure...

10 CFR 1045.4 - Responsibilities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... declassification of RD and FRD in accordance with the Atomic Energy Act; (2) In coordination with the DoD, develop regulations to implement the RD and FRD classification system; (3) Determine whether nuclear-related information is RD; (4) Oversee agency implementation of the RD and FRD classification system to ensure...

The relationship between mortality caused by cardiovascular diseases and two climatic factors in densely populated areas in Norway and Ireland.

PubMed

Eng, H; Mercer, J B

2000-10-01

Seasonal variations in mortality due to cardiovascular disease have been demonstrated in many countries, with the highest levels occurring during the coldest months of the year. It has been suggested that this can be explained by cold climate. In this study, we examined the relationship between mortality and two different climatic factors in two densely populated areas (Dublin, Ireland and Oslo/Akershus, Norway). Meteorological data (mean daily air temperatures and wind speed) and registered daily mortality data for three groups of cardiovascular disease for the period 1985-1994 were obtained for the two respective areas. The daily mortality ratio for both men and women of 60 years and older was calculated from the mortality data. The wind chill temperature equivalent was calculated from the Siple and Passels formula. The seasonal variations in mortality were greater in Dublin than in Oslo/Akershus, with mortality being highest in winter. This pattern was similar to that previously shown for the two respective countries as a whole. There was a negative correlation between mortality and both air temperature and wind chill temperature equivalent for all three groups of diseases. The slopes of the linear regression lines describing the relationship between mortality and air temperature were a lot steeper for the Irish data than for the Norwegian data. However, the difference between the steepness of the linear regression lines for the relationship between mortality and wind chill temperature equivalent was considerably less between the two areas. This can be explained by the fact that Dublin is a much windier area than Oslo/Akershus. The results of this study demonstrate that the inclusion of two climatic factors rather than just one changes the impression of the relationship between climate and cardiovascular disease mortality.

Episiotomy: the final cut?

PubMed

Steiner, Naama; Weintraub, Adi Y; Wiznitzer, Arnon; Sergienko, Ruslan; Sheiner, Eyal

2012-12-01

To investigate whether episiotomy prevents 3rd or 4th degree perineal tears in critical conditions such as shoulder dystocia, instrumental deliveries (vacuum or forceps), persistent occiput-posterior position, fetal macrosomia (>4,000 g), and non-reassuring fetal heart rate (NRFHR) patterns. A retrospective study comparing 3rd and 4th degree perineal tears during vaginal deliveries with or without episiotomy, in selected critical conditions was performed. Multiple gestations, preterm deliveries (<37 weeks' gestation) and cesarean deliveries were excluded from the analysis. Stratified analysis (using the Mantel-Haenszel technique) was used to obtain the weighted odds ratio (OR), while controlling for these variables. During the study period, there were 168,077 singleton vaginal deliveries. Of those, 188 (0.1%) had 3rd or 4th degree perineal tears. Vaginal deliveries with episiotomy had statistically significant higher rates of 3rd or 4th degree perineal tears than those without episiotomy (0.2 vs. 0.1%; P<0.001). The association between episiotomy and severe perineal tears remained significant even in the critical conditions. Stratified analysis revealed that the adjusted ORs for 3rd or 4th degree perineal tears in these critical conditions (Macrosomia OR=2.3; instrumental deliveries OR=1.8; NRFHR patterns OR=2.1; occipito-posterior position OR=2.3; and shoulder dystocia OR=2.3) were similar to the crude OR (OR=2.3). Mediolateral episiotomy is an independent risk factor for 3rd or 4th degree perineal tears, even in critical conditions such as shoulder dystocia, instrumental deliveries, occiput-posterior position, fetal macrosomia, and NRFHR. Prophylactic use of episiotomy in these conditions does not seem beneficial if performed to prevent 3rd or 4th degree perineal tears.

Android-assisted physics mobile learning to improve senior high school students' divergent thinking skills and physics HOTS

NASA Astrophysics Data System (ADS)

Mardiana, Nana; Kuswanto, Heru

2017-08-01

The aims of the research concerned here were to reveal (1) the characteristics of Android-assisted PML (physics mobile learning) to improve SMA (sekolah menengah atas, Indonesian senior high school) students' divergent thinking skills and physics HOTS (higher order thinking skills); (2) the feasibility of the Android-assisted PML; and (3) the influence of using the Android-assisted PML on improvement in SMA students' divergent thinking skills and physics HOTS. The7 research was of the R&D (research and development) type, adapted from theBorg-&-Gall development model. The research data were analyzed by means of MANOVA with the significance level of 5%. The results are as follows. (1) The product of the development, a learning media in software form with the android package(apk) format, is named PML (to refer to Physics Mobile Learning), which has such characterictics as being operable with use of Android devicesand being very good in quality in the aspect oflearning, material, software technology, and audiovisual appearance. 2) The developed learning media referred to as PML is appropriate for learning activity according to evaluation by a material expert, a media expert, peer reviewers, and physics teachers as well as according to results of students' tryouts. (3) The use of the Android-assisted PML media product could improve SMA students' divergent thinking skillsand physics HOTS with the respective high-category gain scores of 0.701 and 0.759.

Constructing a Global Learning Partnership in Physiotherapy: An Ireland-Uganda Initiative.

PubMed

O'Sullivan, Cliona; Kazibwe, Herman; Whitehouse, Zillah; Blake, Catherine

2017-01-01

There is a strong correlation between disability and poverty and it is acknowledged that until disability issues are addressed, the goal of poverty reduction in low-income countries is unlikely to be achieved. Despite the high prevalence of disability in developing countries, there remains a significant shortage of rehabilitation professionals as highlighted by the WHO report, Human resources for Health (2006). The purpose of this project was to develop a collaborative and sustainable partnership to strengthen educational and research capacity in global health, disability, and rehabilitation between two physiotherapy schools; University College Dublin, Ireland, and Mbarara University of Science and Technology, Uganda. This article aims to describe the approach used and initial project outcomes. This project involved a bilateral visit to both institutions by two members of staff of respective physiotherapy programs. These visits entailed stakeholder meetings, clinical site visits, and workshops to identify the priorities for the partnership and shape the collaboration going forward. Appreciative inquiry methodology was used during the workshops and the four-dimensional framework for curriculum development was used to guide analysis and underpin findings. The key priorities identified were (i) development of joint global health learning initiative, (ii) to explore the possibility of postgraduate learning and research opportunities for Ugandan colleagues, and (iii) to develop joint clinical placements. The rationale and context and a plan of action is described. The project is ambitious and in order to be sustainable, the importance of long-term interinstitutional commitment and further funding cannot be ignored. This work provides a framework for other universities and institutions wishing to undertake similar activities. Such partnerships provide rich learning opportunities for students and health professionals and facilitate a deeper understanding of global health issues, social and cultural health determinants, and development of enhanced professional skills.

Accuracy in identifying the elbow rotation axis on simulated fluoroscopic images using a new anatomical landmark.

PubMed

Wiggers, J K; Snijders, R M; Dobbe, J G G; Streekstra, G J; den Hartog, D; Schep, N W L

2017-11-01

External fixation of the elbow requires identification of the elbow rotation axis, but the accuracy of traditional landmarks (capitellum and trochlea) on fluoroscopy is limited. The relative distance (RD) of the humerus may be helpful as additional landmark. The first aim of this study was to determine the optimal RD that corresponds to an on-axis lateral image of the elbow. The second aim was to assess whether the use of the optimal RD improves the surgical accuracy to identify the elbow rotation axis on fluoroscopy. CT scans of elbows from five volunteers were used to simulate fluoroscopy; the actual rotation axis was calculated with CT-based flexion-extension analysis. First, three observers measured the optimal RD on simulated fluoroscopy. The RD is defined as the distance between the dorsal part of the humerus and the projection of the posteromedial cortex of the distal humerus, divided by the anteroposterior diameter of the humerus. Second, eight trauma surgeons assessed the elbow rotation axis on simulated fluoroscopy. In a preteaching session, surgeons used traditional landmarks. The surgeons were then instructed how to use the optimal RD as additional landmark in a postteaching session. The deviation from the actual rotation axis was expressed as rotational and translational error (±SD). Measurement of the RD was robust and easily reproducible; the optimal RD was 45%. The surgeons identified the elbow rotation axis with a mean rotational error decreasing from 7.6° ± 3.4° to 6.7° ± 3.3° after teaching how to use the RD. The mean translational error decreased from 4.2 ± 2.0 to 3.7 ± 2.0 mm after teaching. The humeral RD as additional landmark yielded small but relevant improvements. Although fluoroscopy-based external fixator alignment to the elbow remains prone to error, it is recommended to use the RD as additional landmark.

76 FR 71867 - Addition of Certain Persons to the Entity List; and Implementation of Entity List Annual Review...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-21

.... Microrayan 3rd Apt. 45, block 21, Kabul, Afghanistan, and A2 Ground Floor, City Computer Plaza, Shar-e-Naw... --Ibrahim Walid Microrayan 3rd Apt. 45, Block No. 21, Kabul, Afghanistan. China (1) Xian Semi Electronic Co.... --Farid; and 744.11 of the --Engineer Idris. EAR). Microrayan 3rd Apt. 45, block 21, Kabul, Afghanistan...

Effects of Intensive Fluency Instruction on the Reading Proficiency of Third-Grade Struggling Readers

ERIC Educational Resources Information Center

Rasinski, Timothy; Paige, David; Rains, Cameron; Stewart, Fran; Julovich, Brenda; Prenkert, Deb; Rupley, William H.; Nichols, William Dee

2017-01-01

The present study examined the impact of an intensive reading fluency intervention on the overall reading performance of 37 struggling readers in 3rd grade. Students' 3rd-grade classroom teachers and/or their performance on a state-mandated reading achievement test given toward the end of the 3rd-grade school year identified them for the study.…

77 FR 40479 - Airworthiness Directives; Rolls-Royce Corporation Turboshaft Engines

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-10

... inspection (FPI) on certain 3rd and 4th stage turbine wheels for cracks in the turbine blades. We are issuing this AD to prevent failure of 3rd or 4th stage turbine wheel blades which could cause engine failure... certain 3rd and 4th stage turbine wheels for cracks in the turbine blades. Comments We gave the public the...

A Kinesthetic Learning Approach to Earth Science for 3rd and 4th Grade Students on the Pajarito Plateau, Los Alamos, NM

NASA Astrophysics Data System (ADS)

Wershow, H. N.; Green, M.; Stocker, A.; Staires, D.

2010-12-01

Current efforts towards Earth Science literacy in New Mexico are guided by the New Mexico Science Benchmarks [1]. We are geoscience professionals in Los Alamos, NM who believe there is an important role for non-traditional educators utilizing innovative teaching methods. We propose to further Earth Science literacy for local 3rd and 4th grade students using a kinesthetic learning approach, with the goal of fostering an interactive relationship between the students and their geologic environment. We will be working in partnership with the Pajarito Environmental Education Center (PEEC), which teaches the natural heritage of the Pajarito Plateau to 3rd and 4th grade students from the surrounding area, as well as the Family YMCA’s Adventure Programs Director. The Pajarito Plateau provides a remarkable geologic classroom because minimal structural features complicate the stratigraphy and dramatic volcanic and erosional processes are plainly on display and easily accessible. Our methodology consists of two approaches. First, we will build an interpretive display of the local geology at PEEC that will highlight prominent rock formations and geologic processes seen on a daily basis. It will include a simplified stratigraphic section with field specimens and a map linked to each specimen’s location to encourage further exploration. Second, we will develop and implement a kinesthetic curriculum for an exploratory field class. Active engagement with geologic phenomena will take place in many forms, such as a scavenger hunt for precipitated crystals in the vesicles of basalt flows and a search for progressively smaller rhyodacite clasts scattered along an actively eroding canyon. We believe students will be more receptive to origin explanations when they possess a piece of the story. Students will be provided with field books to make drawings of geologic features. This will encourage independent assessment of phenomena and introduce the skill of scientific observation. We expect students to develop comprehension of basic geologic concepts and processes such as erosion and sediment transport, caldera formation, ash flows, crystallization and volcanic cooling features. More importantly, we hope students will become excited about their geologic environment and pursue further engagement. We will attempt to quantify student comprehension and engagement by administering simple questionnaires before and after exposure to both the PEEC display and the field class. ____________________________________________________________ [1] New Mexico Science Content Standards, Benchmarks, and Performance Standards. Approved 2003, New Mexico State Department of Education. 3rd Grade Benchmark: “Know that Earth’s features are constantly changed by a combination of slow and rapid processes that include the action of volcanoes, earthquakes, mountain building, biological changes, erosion, and weathering” 4th Grade Benchmark: “Know that the properties of rocks and minerals reflect the processes that shaped them (i.e., igneous, metamorphic, and sedimentary rocks)”

Metadata: Pure and Simple, or Is It?

ERIC Educational Resources Information Center

Chalmers, Marilyn

2002-01-01

Discusses issues concerning metadata in Web pages based on experiences in a vocational education center library in Queensland (Australia). Highlights include Dublin Core elements; search engines; controlled vocabulary; performance measurement to assess usage patterns and provide quality control over the vocabulary; and considerations given the…

Towards a Generative Phonology of the Modern Irish Noun

ERIC Educational Resources Information Center

Wigger, Arndt

1973-01-01

Revised version of Komplexe Regelmerkmale in der Morphologie des Irischen'' (Complex Rule Characteristics in Irish Morphology), a paper presented at a meeting of the Societas Linguistica Europaea, Prague, Czechoslovakia, October 10, 1970; present paper presented at the Dublin Linguistic Circle, January 10, 1971. (DD)

The Cognitive and Academic Profiles of Reading and Mathematics Learning Disabilities

PubMed Central

Compton, Donald L.; Fuchs, Lynn S.; Fuchs, Douglas; Lambert, Warren; Hamlett, Carol

2012-01-01

The purpose of this study was to examine the cognitive and academic profiles associated with learning disability (LD) in reading comprehension, word reading, applied problems, and calculations. The goal was to assess the specificity hypothesis, in which unexpected underachievement associated with LD is represented in terms of distinctive patterns of cognitive and academic strengths and weaknesses. At the start of 3rd grade, the authors assessed 684 students on five cognitive dimensions (nonverbal problem solving, processing speed, concept formation, language, and working memory), and across Grades 3 through 5, the authors assessed performance in each academic area three to four times. Based on final intercept, the authors classified students as LD or not LD in each of the four academic areas. For each of these four LD variables, they conducted multivariate cognitive profile analysis and academic profile analysis. Results, which generally supported the specificity hypothesis, are discussed in terms of the potential connections between reading and mathematics LD. PMID:21444929

The cognitive and academic profiles of reading and mathematics learning disabilities.

PubMed

Compton, Donald L; Fuchs, Lynn S; Fuchs, Douglas; Lambert, Warren; Hamlett, Carol

2012-01-01

The purpose of this study was to examine the cognitive and academic profiles associated with learning disability (LD) in reading comprehension, word reading, applied problems, and calculations. The goal was to assess the specificity hypothesis, in which unexpected underachievement associated with LD is represented in terms of distinctive patterns of cognitive and academic strengths and weaknesses. At the start of 3rd grade, the authors assessed 684 students on five cognitive dimensions (nonverbal problem solving, processing speed, concept formation, language, and working memory), and across Grades 3 through 5, the authors assessed performance in each academic area three to four times. Based on final intercept, the authors classified students as LD or not LD in each of the four academic areas. For each of these four LD variables, they conducted multivariate cognitive profile analysis and academic profile analysis. Results, which generally supported the specificity hypothesis, are discussed in terms of the potential connections between reading and mathematics LD.

The development of product parity sensitivity in children with mathematics learning disability and in typical achievers.

PubMed

Rotem, Avital; Henik, Avishai

2013-02-01

Parity helps us determine whether an arithmetic equation is true or false. The current research examines the development of sensitivity to parity cues in multiplication in typically achieving (TA) children (grades 2, 3, 4 and 6) and in children with mathematics learning disabilities (MLD, grades 6 and 8), via a verification task. In TA children the onset of parity sensitivity was observed at the beginning of 3rd grade, whereas in children with MLD it was documented only in 8th grade. These results suggest that children with MLD develop parity aspects of number sense, though later than TA children. To check the plausibility of equations, children used mainly the multiplication parity rule rather than familiarity with even products. Similar to observations in adults, parity sensitivity was largest for problems with two even operands, moderate for problems with one even and one odd operand, and smallest for problems with two odd operands. Copyright © 2012 Elsevier Ltd. All rights reserved.

Brief strategic therapy for obsessive–compulsive disorder: a clinical and research protocol of a one-group observational study

PubMed Central

Pietrabissa, Giada; Manzoni, Gian Mauro; Gibson, Padraic; Boardman, Donald; Gori, Alessio; Castelnuovo, Gianluca

2016-01-01

Introduction Obsessive–compulsive disorder (OCD) is a disabling psychopathology. The mainstay of treatment includes cognitive–behavioural therapy (CBT) and medication management. However, individual suffering, functional impairments as well as the direct and indirect costs associated with the disease remain substantial. New treatment programmes are necessary and the brief strategic therapy (BST) has recently shown encouraging results in clinical practice but no quantitative study has as yet been conducted. Methods and analysis The clinical effectiveness of the OCD-specific BST protocol will be evaluated in a one-group observational study. Participants will be sequentially recruited from a state community psychotherapy clinic in Dublin, Ireland. Outcome measures will be the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) and the Beck Depression Inventory-II (BDI-II). Data will be collected at baseline, at treatment termination and at 3 month follow-up. The statistical significance of the post-treatment effect will be assessed by the paired-sample Student t test, while clinical significance will be evaluated by means of the equivalence testing method, which will be also used to assess the maintenance of effect at follow-up. Ethics/dissemination The present study is approved by the Hesed House Ethics Board in Dublin. Findings will enhance the evidence-based knowledge about the clinical effectiveness of BST in treating OCD symptoms, prior to assessing its efficacy in a randomised and controlled clinical trial, and will be disseminated through publication in peer-reviewed journals and conference presentations. PMID:27013594

Smoking among schoolchildren

PubMed Central

O'Rourke, A. H.; O'Byrne, D. J.; Wilson-Davis, K.

1983-01-01

As part of its health education programme, the Irish Cancer Society sponsored studies of the smoking habits of Dublin schoolchildren in the late 1960s and early 1970s. It was decided to review the situation a decade later, and accordingly the Health Education Bureau, the Medico-Social Research Board and the Irish Cancer Society funded a survey of smokers among Dublin post-primary schoolchildren in 1981. The prevalance of smoking among schoolchildren is still at a high level, and the main change over the last 10 years has been the fact that girls have almost caught up with the boys. It was hard to evaluate the effect of health education over the decade. Although many of the `smoking' students wanted to give up smoking the reason was not long-term health. In fact, concentrating on the `cancer/shorten life' effects of smoking may be counterproductive and anti-smoking campaigns should perhaps stress the immediate benefits of giving up smoking-better breathing, increased ability for sport, saving of money, and so on. PMID:6631802

Diarrhea, stimulation and growth predict neurodevelopment in young North Indian children.

PubMed

Kvestad, Ingrid; Taneja, Sunita; Hysing, Mari; Kumar, Tivendra; Bhandari, Nita; Strand, Tor A

2015-01-01

Infants and young children in low to middle-income countries are at risk for adverse neurodevelopment due to multiple risk factors. In this study, we sought to identify stimulation and learning opportunities, growth, and burden of respiratory infections and diarrhea as predictors for neurodevelopment. We visited 422 North Indian children 6 to 30 months old weekly for six months. Childhood illnesses were assessed biweekly. At end study, we assessed neurodevelopment using the Ages and Stages Questionnaire 3rd ed. (ASQ-3) and gathered information on stimulation and learning opportunities. We identified predictors for ASQ-3 scores in multiple linear and logistic regression models. We were able to explain 30.5% of the variation in the total ASQ-3 score by the identified predictors. When adjusting for child characteristics and annual family income, stimulation and learning opportunities explained most of the variation by 25.1%. Height for age (standardized beta: 0.12, p<.05) and weight for height z-scores (std. beta: 0.09, p<.05) were positively associated with the total ASQ-3 score, while number of days with diarrhea was negatively associated with these scores (std. beta: -0.13, p<0.01). Our results support the importance of early child stimulation and general nutrition for child development. Our study also suggests that diarrhea is an additional risk factor for adverse neurodevelopment in vulnerable children.

Who am I now? The experience of being a post-registration children's student nurse in the first clinical placement.

PubMed

Begley, Thelma

2007-07-01

Role transition from staff nurse to post-registration student is not a well researched area of nursing. Two previous Irish studies have been reported of the experiences of post-registration midwifery students [McCrea, H., Thompson, K., Carswell, L., Whittington, D., 1994. Student midwives' learning experience on the wards. Journal of Clinical Nursing 3, 97-102; Begley, C., 1997. Midwives in the making: a longitudinal study of the experiences of student midwives during their two-year training in Ireland. Unpublished PhD Thesis, School of Nursing and Midwifery, Trinity College, Dublin.] but there is limited research into post-registration children's student nurses experiences. A broadly phenomenological approach was employed to interpret what it means to be a post-registration children's student nurse during the first clinical placement. Data was collected from a purposive sample of six students, using unstructured tape recorded interviews. Thematic content analysis was utilised to produce an interpretation of nurses' experience within the first clinical placement. The findings reflect the participants' role confusion when changing from being a staff nurse in one discipline of nursing to being a post-registration student in another. They find previous experience is not recognised and that students originating from different disciplines in nursing have different experiences within the first placement. Coping mechanisms are discussed along with preparation for and supports available in the clinical area.

ATLAS Cloud R&D

NASA Astrophysics Data System (ADS)

Panitkin, Sergey; Barreiro Megino, Fernando; Caballero Bejar, Jose; Benjamin, Doug; Di Girolamo, Alessandro; Gable, Ian; Hendrix, Val; Hover, John; Kucharczyk, Katarzyna; Medrano Llamas, Ramon; Love, Peter; Ohman, Henrik; Paterson, Michael; Sobie, Randall; Taylor, Ryan; Walker, Rodney; Zaytsev, Alexander; Atlas Collaboration

2014-06-01

The computing model of the ATLAS experiment was designed around the concept of grid computing and, since the start of data taking, this model has proven very successful. However, new cloud computing technologies bring attractive features to improve the operations and elasticity of scientific distributed computing. ATLAS sees grid and cloud computing as complementary technologies that will coexist at different levels of resource abstraction, and two years ago created an R&D working group to investigate the different integration scenarios. The ATLAS Cloud Computing R&D has been able to demonstrate the feasibility of offloading work from grid to cloud sites and, as of today, is able to integrate transparently various cloud resources into the PanDA workload management system. The ATLAS Cloud Computing R&D is operating various PanDA queues on private and public resources and has provided several hundred thousand CPU days to the experiment. As a result, the ATLAS Cloud Computing R&D group has gained a significant insight into the cloud computing landscape and has identified points that still need to be addressed in order to fully utilize this technology. This contribution will explain the cloud integration models that are being evaluated and will discuss ATLAS' learning during the collaboration with leading commercial and academic cloud providers.

The effects of an online basic life support course on undergraduate nursing students' learning.

PubMed

Tobase, Lucia; Peres, Heloisa H C; Gianotto-Oliveira, Renan; Smith, Nicole; Polastri, Thatiane F; Timerman, Sergio

2017-08-25

To describe learning outcomes of undergraduate nursing students following an online basic life support course (BLS). An online BLS course was developed and administered to 94 nursing students. Pre- and post-tests were used to assess theoretical learning. Checklist simulations and feedback devices were used to assess the cardiopulmonary resuscitation (CPR) skills of the 62 students who completed the course. A paired t-test revealed a significant increase in learning [pre-test (6.4 ± 1.61), post-test (9.3 ± 0.82), p < 0.001]. The increase in the average grade after taking the online course was significant (p<0.001). No learning differences (p=0.475) had been observed between 1st and 2nd year (9.20 ± 1.60), and between 3rd and 4th year (9.67 ± 0.61) students. A CPR simulation was performed after completing the course: students checked for a response (90%), exposed the chest (98%), checked for breathing (97%), called emergency services (76%), requested for a defibrillator (92%), checked for a pulse (77%), positioned their hands properly (87%), performed 30 compressions/cycle (95%), performed compressions of at least 5 cm depth (89%), released the chest (90%), applied two breaths (97%), used the automated external defibrillator (97%), and positioned the pads (100%). The online course was an effective method for teaching and learning key BLS skills wherein students were able to accurately apply BLS procedures during the CPR simulation. This short-term online training, which likely improves learning and self-efficacy in BLS providers, can be used for the continuing education of health professionals.

IMACS 󈨟: Proceedings of the IMACS World Congress on Computation and Applied Mathematics (13th) Held in Dublin, Ireland on July 22-26, 1991. Volume 4. Modelling and Simulation for Electrical, Electronic and Semiconductor Devices, Computation for Management Systems, Applications of Modelling and Simulation, Environmental Systems Simulation, Software Forum, Poster Sessions

DTIC Science & Technology

1991-07-01

synchronous machine case study . IEEE T rons. on For the ease nd -nq -2, four time scales trust be used And the A.C, Vol. 36. nul 3, March 1989. damnper... studied . A spot welded(Csse 3) * ss s i* r 0. or a line welded( Case 4) reinforcement plate is attached on the colliding surface of box beams arnd their...phased armature, is given on Figure 1. analytical field calculation in the machine magnetic structure. Il - MAGNETIC STRUCTURE MODELLING: In the case

Children, Families, and Public Schools: Building Community Alliances for Learning. The National Education Association's Annual Conference on Human and Civil Rights in Education (23rd, February 22-24, 1985). NEA Report.

ERIC Educational Resources Information Center

National Education Association, Washington, DC.

This conference addressed the problems of children whose circumstances limit their ability to learn, their access to equal educational opportunity, and their basic civil rights, and the role of National Education Association (NEA) members and their communities in solving these problems. The keynote address by Blandina Cardenas Ramirez, excerpted…

PreK-3rd: Next Steps for State Longitudinal Data Systems. PreK-3rd Policy Action Brief. No. Eight

ERIC Educational Resources Information Center

Hernandez, Donald J.

2012-01-01

The growing movement to strengthen PreK-3rd education as an essential foundation for student success, along with the rapid expansion in public funding for PreK, has created an urgent need to measure children's educational progress, in a continuous fashion, from the beginning of PreK through Grade Three. Currently, some state governments are…

Do 2nd and 3rd Grade Teachers' Linguistic Knowledge and Instructional Practices Predict Spelling Gains in Weaker Spellers?

ERIC Educational Resources Information Center

Puliatte, Alison; Ehri, Linnea C.

2018-01-01

The relationship between 2nd and 3rd grade teachers' linguistic knowledge and spelling instructional practices and their students' spelling gains from fall to spring was examined. Second grade (N = 16) and 3rd grade (N = 16) teachers were administered an instructional practices survey and a linguistic knowledge test. Total scores on the two…

The proto-oncoprotein FBI-1 interacts with MBD3 to recruit the Mi-2/NuRD-HDAC complex and BCoR and to silence p21WAF/CDKN1A by DNA methylation.

PubMed

Choi, Won-Il; Jeon, Bu-Nam; Yoon, Jae-Hyeon; Koh, Dong-In; Kim, Myung-Hwa; Yu, Mi-Young; Lee, Kyung-Mi; Kim, Youngsoo; Kim, Kyunggon; Hur, Sujin Susanne; Lee, Choong-Eun; Kim, Kyung-Sup; Hur, Man-Wook

2013-07-01

The tumour-suppressor gene CDKN1A (encoding p21Waf/Cip1) is thought to be epigenetically repressed in cancer cells. FBI-1 (ZBTB7A) is a proto-oncogenic transcription factor repressing the alternative reading frame and p21WAF/CDKN1A genes of the p53 pathway. FBI-1 interacts directly with MBD3 (methyl-CpG-binding domain protein 3) in the nucleus. We demonstrated that FBI-1 binds both non-methylated and methylated DNA and that MBD3 is recruited to the CDKN1A promoter through its interaction with FBI-1, where it enhances transcriptional repression by FBI-1. FBI-1 also interacts with the co-repressors nuclear receptor corepressor (NCoR), silencing mediator for retinoid and thyroid receptors (SMRT) and BCL-6 corepressor (BCoR) to repress transcription. MBD3 regulates a molecular interaction between the co-repressor and FBI-1. MBD3 decreases the interaction between FBI-1 and NCoR/SMRT but increases the interaction between FBI-1 and BCoR. Because MBD3 is a subunit of the Mi-2 autoantigen (Mi-2)/nucleosome remodelling and histone deacetylase (NuRD)-HDAC complex, FBI-1 recruits the Mi-2/NuRD-HDAC complex via MBD3. BCoR interacts with the Mi-2/NuRD-HDAC complex, DNMTs and HP1. MBD3 and BCoR play a significant role in the recruitment of the Mi-2/NuRD-HDAC complex- and the NuRD complex-associated proteins, DNMTs and HP. By recruiting DNMTs and HP1, Mi-2/NuRD-HDAC complex appears to play key roles in epigenetic repression of CDKN1A by DNA methylation.

Memory and comprehension deficits in spatial descriptions of children with non-verbal and reading disabilities.

PubMed

Mammarella, Irene C; Meneghetti, Chiara; Pazzaglia, Francesca; Cornoldi, Cesare

2014-01-01

The present study investigated the difficulties encountered by children with non-verbal learning disability (NLD) and reading disability (RD) when processing spatial information derived from descriptions, based on the assumption that both groups should find it more difficult than matched controls, but for different reasons, i.e., due to a memory encoding difficulty in cases of RD and to spatial information comprehension problems in cases of NLD. Spatial descriptions from both survey and route perspectives were presented to 9-12-year-old children divided into three groups: NLD (N = 12); RD (N = 12), and typically developing controls (TD; N = 15); then participants completed a sentence verification task and a memory for locations task. The sentence verification task was presented in two conditions: in one the children could refer to the text while answering the questions (i.e., text present condition), and in the other the text was withdrawn (i.e., text absent condition). Results showed that the RD group benefited from the text present condition, but was impaired to the same extent as the NLD group in the text absent condition, suggesting that the NLD children's difficulty is due mainly to their poor comprehension of spatial descriptions, while the RD children's difficulty is due more to a memory encoding problem. These results are discussed in terms of their implications in the neuropsychological profiles of children with NLD or RD, and the processes involved in spatial descriptions.

Worldwide Market For Scientific Lasers

NASA Astrophysics Data System (ADS)

Westra, Sicco

1989-06-01

I'm going to talk about the worldwide market for scientific lasers. I felt we should start with a quote from our soon-to-be President and learn from him how he feels about the commitment that the government should make to R&D. "R&D is the economic Fountain of Youth, and we really should take good care of it because that is where our business is for the future." If you read through that quote, it is very clear that at least before the election, he made a very strong commitment to this. It will be interesting to see over the next four years whether he keeps to that commitment or not, but I happen to totally agree with what he is saying here. The R&D market, as I see it, is certainly, as far as lasers are concerned, the growth place for new technology and applications.

27 CFR 9.46 - Livermore Valley.

Code of Federal Regulations, 2011 CFR

2011-04-01

....” (b) Approved maps. The appropriate maps for determining the boundary of the Livermore Valley... 1980); (12) Hayward, CA (1993); and (13) Las Trampas Ridge, CA (1995). (c) Boundary. The Livermore... miles, passing through the Dublin map near Walpert Ridge, onto the Hayward map to the point where the...

27 CFR 9.46 - Livermore Valley.

Code of Federal Regulations, 2010 CFR

2010-04-01

....” (b) Approved maps. The appropriate maps for determining the boundary of the Livermore Valley... 1980); (12) Hayward, CA (1993); and (13) Las Trampas Ridge, CA (1995). (c) Boundary. The Livermore... miles, passing through the Dublin map near Walpert Ridge, onto the Hayward map to the point where the...

us9805_latilt

Science.gov Websites

;meta http-equiv=Content-Type content="text/html; charset=iso-8859-1"> <meta name=ProgId content=Word.Document> <meta name=Generator content="Microsoft Word 11"> <meta name /dublin_core"> <meta name=dc.title content="Alaska Solar Resource: Flat Plate Collector, Facing

William E. Wilson and his contemporaries

NASA Astrophysics Data System (ADS)

Elliott, I.

Although he never attended school or university, William E. Wilson FRS, of Daramona, County Westmeath, made pioneering contributions to solar physics, celestial photography and stellar photometry. His well-equipped observatory attracted collaborators who included George Francis FitzGerald of Trinity College Dublin and Arthur Rambaut of Dunsink Observatory.

Core Skills Assessment to Improve Mathematical Competency

ERIC Educational Resources Information Center

Carr, Michael; Bowe, Brian; Ní Fhloinn, Eabhnat

2013-01-01

Many engineering undergraduates begin third-level education with significant deficiencies in their core mathematical skills. Every year, in the Dublin Institute of Technology, a diagnostic test is given to incoming first-year students, consistently revealing problems in basic mathematics. It is difficult to motivate students to address these…

Language across Cultures. Proceedings of a Symposium (St. Patrick's College, Dublin, Ireland, July 8-9, 1983).

ERIC Educational Resources Information Center

Mathuna, Liam Mac; Singleton, David

Papers presented at the symposium on the relationship between language and culture include, in addition to an opening adress: "Sociosemiotics Across Cultures" (Wolfgang Kuhlwein); "Translation Across Languages or Across Cultures?" (Albrecht Neubert); "Grammatical Categories Across Cultures" (Olga Tomic); "On…

Careers and people

NASA Astrophysics Data System (ADS)

2013-01-01

On his staff page of the Trinity College Dublin website, Michael Coey lists "champagne" as his favourite drink. At the end of 2012, the Belfast-born experimental physicist received an extra reason to raise a celebratory glass thanks to Science Foundation Ireland (SFI), which named him its Researcher of the Year.

The penalty points system in Ireland - Does it remain effective 14 years on?

PubMed

Downey, C; Donnelly, M

2018-06-01

Road traffic accidents (RTAs) are the leading cause of trauma related mortality in Ireland. The penalty points system (PPS) was introduced in Ireland in 2002 to incentivise safer driving and reduce injury. Its early effect was studied previously 1 which concluded that there was a slight reduction in RTA related femoral shaft fractures (a sensitive indicator of high energy trauma) and a dramatic reduction in RTA related discharges. We hypothesized that over the following 14 years, the penalty points system might lose its effectiveness. Data was again collected from the same HIPE departments from six Dublin teaching hospitals and also University Hospital Waterford (to represent both an urban and a more rural population cohort respectively) examining RTA related femoral shaft fractures over an identical 6 month period (October-April). RTA related discharge data over an identical 6 month period was again acquired and analysed from Beaumont Hospital, Dublin (identical data source to previous study). These results were compared with the identical 6 month period in 2001/02 & 2002/03 (October-April). The total number of RTA related femoral shaft fracture discharges in Dublin decreased from 16 post introduction of PPS in the 2002/03 6-month period to 7 in 2015/16 6-month period. The number remained the same in the Waterford region (n = 5). The total RTA related discharges in Beaumont Hospital, Dublin decreased from 70 post PPS introduction to 57 in the 2015/16 6-month period. This represents an incidence rate of 4.5/1000 discharges (vs 6.9 post introduction) which was a statistically significant reduction (p = 0.014). The mean length of stay for these patients reduced from 13 to 7.7 days. There were consistent reductions in head injury (major & minor), lower limb fracture and facial fracture since the introduction of the PPS. The upper limb, pelvic/acetabular and thoracic injuries remained largely unchanged. Whilst RTA related spinal and abdominal injuries decreased after the introduction of the PPS, this study shows that these injuries have unfortunately increased since the post-PPS study in 2002/03. These results further support the effectiveness of the penalty points system and at a time where road death figures are under the spotlight, endorse the efficacious strategies implemented by the road safety authority in Ireland. Copyright © 2017 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.

Testing two approaches to revictimization prevention among adolescent girls in the child welfare system.

PubMed

DePrince, Anne P; Chu, Ann T; Labus, Jennifer; Shirk, Stephen R; Potter, Cathryn

2015-02-01

Girls in the child welfare system are at high risk of revictimization in adolescence. The present study compared two interventions designed to decrease revictimization in a diverse sample of adolescent child welfare-involved girls. The social learning/feminist (SL/F) intervention focused on concepts derived from social learning and feminist models of risk, such as sexism and beliefs about relationships. The risk detection/executive function (RD/EF) intervention focused on development of specific executive function abilities related to detecting and responding to risky situations/people. Participants were randomized to RD/EF (n = 67) or SL/F intervention (n = 67). A group of youth (n = 42) engaged in the research assessments only. Participants (n = 180) were assessed before intervention, immediately after intervention, 2 months after intervention, and 6 months after intervention. We examined revictimization (the presence/absence of sexual or physical assault in any relationship) over time. Adolescent girls in the RD/EF condition were nearly five times less likely to report sexual revictimization compared with girls in the no-treatment group. A trend suggested that girls who participated in the SL/F intervention were 2.5 times less likely to report sexual revictimization relative to the no-treatment group. For physical revictimization, the odds of not being physically revictimized were three times greater in the SL/F condition and two times greater in the RD/EF condition compared with the no-treatment group. The active interventions did not differ significantly from one another in rates of revictimization, suggesting that practitioners have at least two viable options to engage high-risk youth in revictimization prevention. Copyright © 2015 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

Variable phenotypic expressivity in inbred retinal degeneration mouse lines: A comparative study of C3H/HeOu and FVB/N rd1 mice.

PubMed

van Wyk, Michiel; Schneider, Sabine; Kleinlogel, Sonja

2015-01-01

Recent advances in optogenetics and gene therapy have led to promising new treatment strategies for blindness caused by retinal photoreceptor loss. Preclinical studies often rely on the retinal degeneration 1 (rd1 or Pde6b(rd1)) retinitis pigmentosa (RP) mouse model. The rd1 founder mutation is present in more than 100 actively used mouse lines. Since secondary genetic traits are well-known to modify the phenotypic progression of photoreceptor degeneration in animal models and human patients with RP, negligence of the genetic background in the rd1 mouse model is unwarranted. Moreover, the success of various potential therapies, including optogenetic gene therapy and prosthetic implants, depends on the progress of retinal degeneration, which might differ between rd1 mice. To examine the prospect of phenotypic expressivity in the rd1 mouse model, we compared the progress of retinal degeneration in two common rd1 lines, C3H/HeOu and FVB/N. We followed retinal degeneration over 24 weeks in FVB/N, C3H/HeOu, and congenic Pde6b(+) seeing mouse lines, using a range of experimental techniques including extracellular recordings from retinal ganglion cells, PCR quantification of cone opsin and Pde6b transcripts, in vivo flash electroretinogram (ERG), and behavioral optokinetic reflex (OKR) recordings. We demonstrated a substantial difference in the speed of retinal degeneration and accompanying loss of visual function between the two rd1 lines. Photoreceptor degeneration and loss of vision were faster with an earlier onset in the FVB/N mice compared to C3H/HeOu mice, whereas the performance of the Pde6b(+) mice did not differ significantly in any of the tests. By postnatal week 4, the FVB/N mice expressed significantly less cone opsin and Pde6b mRNA and had neither ERG nor OKR responses. At 12 weeks of age, the retinal ganglion cells of the FVB/N mice had lost all light responses. In contrast, 4-week-old C3H/HeOu mice still had ERG and OKR responses, and we still recorded light responses from C3H/HeOu retinal ganglion cells until the age of 24 weeks. These results show that genetic background plays an important role in the rd1 mouse pathology. Analogous to human RP, the mouse genetic background strongly influences the rd1 phenotype. Thus, different rd1 mouse lines may follow different timelines of retinal degeneration, making exact knowledge of genetic background imperative in all studies that use rd1 models.

PET imaging predicts future body weight and cocaine preference

DOE Office of Scientific and Technical Information (OSTI.GOV)

Michaelides M.; Wang G.; Michaelides M.

Deficits in dopamine D2/D3 receptor (D2R/D3R) binding availability using PET imaging have been reported in obese humans and rodents. Similar deficits have been reported in cocaine-addicts and cocaine-exposed primates. We found that D2R/D3R binding availability negatively correlated with measures of body weight at the time of scan (ventral striatum), at 1 (ventral striatum) and 2 months (dorsal and ventral striatum) post scan in rats. Cocaine preference was negatively correlated with D2R/D3R binding availability 2 months (ventral striatum) post scan. Our findings suggest that inherent deficits in striatal D2R/D3R signaling are related to obesity and drug addiction susceptibility and that ventralmore » and dorsal striatum serve dissociable roles in maintaining weight gain and cocaine preference. Measuring D2R/D3R binding availability provides a way for assessing susceptibility to weight gain and cocaine abuse in rodents and given the translational nature of PET imaging, potentially primates and humans.« less

Cargo Movement Operations System (CMOS). Updated Software Requirements Specifications, Increment 2, (Communications CSCI)

DTIC Science & Technology

1990-11-14

NO [ ] COMMENT DISPOSITION: COMMENT STATUS: OPEN [ ] CLOSED [ ] ORIGINATOR CONTROL NUMBER: SRS2-0002 PROGRAM OFFICE CONTROL NUMBER: DATA ITEM...e. (1st and 3rd sentence), 3.2.7.21, and 3.2.8 b. CMOS PMO ACCEPTS COMMENT: YES [ ] NO [ ] ERCI ACCEPTS COMMENT: YES [ ] NO [ COMMENT DISPOSITION...3rd 3.2.7.6 4th 3.2.7.22 4th 3.2.7.7 4th 3.2.8 d. 2nd & 3rd 3.2.7.9 4th 3.2.8 e. 2nd CMOS PMO ACCEPTS COMMENT: YES [ ] NO [ ] ERCI ACCEPTS COMMENT: YES [ ] NO [ ] COMMENT DISPOSITION: COMMENT STATUS: OPEN [

How Should Municipal Police Agencies Participate in America’s Homeland Security Strategy?

DTIC Science & Technology

2008-12-01

NonProfit Organizations: A Guide to Strengthening and Sustaining Organizational Achievement, 3rd ed. (San Francisco, CA: Jossey- Bass , 2004). 43 Ibid 36...Planning for Public and NonProfit Organizations: A Guide to Strengthening and Sustaining Organizational Achievement, 3rd ed. (San Francisco, CA: Jossey- Bass ...Public and NonProfit Organizations: A Guide to Strengthening and Sustaining Organizational Achievement, 3rd ed. (San Francisco, CA: Jossey- Bass , 2004

CUSTOM OPTIMIZATION OF INTRAOCULAR LENS ASPHERICITY

PubMed Central

Koch, Douglas D.; Wang, Li

2007-01-01

Purpose To investigate the optimal amount of ocular spherical aberration (SA) in an intraocular lens (IOL) to maximize optical quality. Methods In 154 eyes of 94 patients aged 40 to 80 years, implantation of aspheric IOLs was simulated with different amounts of SA to produce residual ocular SA from −0.30 μm to +0.30 μm. Using the VOL-CT program (Sarver & Associates, Carbondale, Illinois), corneal wavefront aberrations up to 6th order were computed from corneal topographic elevation data (Humphrey Atlas, Carl Zeiss Meditec, Inc, Dublin, California). Using the ZernikeTool program (Advanced Medical Optics, Inc, Santa Ana, California), the polychromatic point spread function with Stiles-Crawford effect was calculated for the residual ocular higher-order aberrations (HOAs, 3rd to 6th order, 6-mm pupil), assuming fully corrected 2nd-order aberrations. Five parameters were used to quantify optical image quality, and we determined the residual ocular SA at which the maximal image quality was achieved for each eye. Stepwise multiple regression analysis was performed to assess the predictors for optimal SA of each eye. Results The optimal SA varied widely among eyes. Most eyes had best image quality with low amounts of negative SA. For modulation transfer function volume up to 15 cycles/degree, the amount of optimal SA could be predicted based on other HOAs of the cornea with coefficient of multiple determination (R2) of 79%. Eight Zernike terms significantly contributed to the optimal SA in this model; the order of importance to optimal SA from most to least was: Z60, Z62, Z42, Z53, Z64, Z3−1, Z33, and Z31. For the other 4 measures of visual quality, the coefficients of determination varied from 32% to 63%. Conclusion The amount of ocular SA producing best image quality varied widely among subjects and could be predicted based on corneal HOAs. Selection of an aspheric IOL should be customized according to the full spectrum of corneal HOAs and not 4th-order SA alone. PMID:18427592

Competency in ECG Interpretation Among Medical Students

PubMed Central

Kopeć, Grzegorz; Magoń, Wojciech; Hołda, Mateusz; Podolec, Piotr

2015-01-01

Background Electrocardiogram (ECG) is commonly used in diagnosis of heart diseases, including many life-threatening disorders. We aimed to assess skills in ECG interpretation among Polish medical students and to analyze the determinants of these skills. Material/Methods Undergraduates from all Polish medical schools were asked to complete a web-based survey containing 18 ECG strips. Questions concerned primary ECG parameters (rate, rhythm, and axis), emergencies, and common ECG abnormalities. Analysis was restricted to students in their clinical years (4th–6th), and students in their preclinical years (1st–3rd) were used as controls. Results We enrolled 536 medical students (females: n=299; 55.8%), aged 19 to 31 (23±1.6) years from all Polish medical schools. Most (72%) were in their clinical years. The overall rate of good response was better in students in years 4th–5th than those in years 1st–3rd (66% vs. 56%; p<0.0001). Competency in ECG interpretation was higher in students who reported ECG self-learning (69% vs. 62%; p<0.0001) but no difference was found between students who attended or did not attend regular ECG classes (66% vs. 66%; p=0.99). On multivariable analysis (p<0.0001), being in clinical years (OR: 2.45 [1.35–4.46] and self-learning (OR: 2.44 [1.46–4.08]) determined competency in ECG interpretation. Conclusions Polish medical students in their clinical years have a good level of competency in interpreting the primary ECG parameters, but their ability to recognize ECG signs of emergencies and common heart abnormalities is low. ECG interpretation skills are determined by self-education but not by attendance at regular ECG classes. Our results indicate qualitative and quantitative deficiencies in teaching ECG interpretation at medical schools. PMID:26541993

Specific Learning Disorder: Prevalence and Gender Differences

PubMed Central

Moll, Kristina; Kunze, Sarah; Neuhoff, Nina; Bruder, Jennifer; Schulte-Körne, Gerd

2014-01-01

Comprehensive models of learning disorders have to consider both isolated learning disorders that affect one learning domain only, as well as comorbidity between learning disorders. However, empirical evidence on comorbidity rates including all three learning disorders as defined by DSM-5 (deficits in reading, writing, and mathematics) is scarce. The current study assessed prevalence rates and gender ratios for isolated as well as comorbid learning disorders in a representative sample of 1633 German speaking children in 3rd and 4th Grade. Prevalence rates were analysed for isolated as well as combined learning disorders and for different deficit criteria, including a criterion for normal performance. Comorbid learning disorders occurred as frequently as isolated learning disorders, even when stricter cutoff criteria were applied. The relative proportion of isolated and combined disorders did not change when including a criterion for normal performance. Reading and spelling deficits differed with respect to their association with arithmetic problems: Deficits in arithmetic co-occurred more often with deficits in spelling than with deficits in reading. In addition, comorbidity rates for arithmetic and reading decreased when applying stricter deficit criteria, but stayed high for arithmetic and spelling irrespective of the chosen deficit criterion. These findings suggest that the processes underlying the relationship between arithmetic and reading might differ from those underlying the relationship between arithmetic and spelling. With respect to gender ratios, more boys than girls showed spelling deficits, while more girls were impaired in arithmetic. No gender differences were observed for isolated reading problems and for the combination of all three learning disorders. Implications of these findings for assessment and intervention of learning disorders are discussed. PMID:25072465

Specific learning disorder: prevalence and gender differences.

PubMed

Moll, Kristina; Kunze, Sarah; Neuhoff, Nina; Bruder, Jennifer; Schulte-Körne, Gerd

2014-01-01

Comprehensive models of learning disorders have to consider both isolated learning disorders that affect one learning domain only, as well as comorbidity between learning disorders. However, empirical evidence on comorbidity rates including all three learning disorders as defined by DSM-5 (deficits in reading, writing, and mathematics) is scarce. The current study assessed prevalence rates and gender ratios for isolated as well as comorbid learning disorders in a representative sample of 1633 German speaking children in 3rd and 4th Grade. Prevalence rates were analysed for isolated as well as combined learning disorders and for different deficit criteria, including a criterion for normal performance. Comorbid learning disorders occurred as frequently as isolated learning disorders, even when stricter cutoff criteria were applied. The relative proportion of isolated and combined disorders did not change when including a criterion for normal performance. Reading and spelling deficits differed with respect to their association with arithmetic problems: Deficits in arithmetic co-occurred more often with deficits in spelling than with deficits in reading. In addition, comorbidity rates for arithmetic and reading decreased when applying stricter deficit criteria, but stayed high for arithmetic and spelling irrespective of the chosen deficit criterion. These findings suggest that the processes underlying the relationship between arithmetic and reading might differ from those underlying the relationship between arithmetic and spelling. With respect to gender ratios, more boys than girls showed spelling deficits, while more girls were impaired in arithmetic. No gender differences were observed for isolated reading problems and for the combination of all three learning disorders. Implications of these findings for assessment and intervention of learning disorders are discussed.

Sensitivity and specificity of machine learning classifiers for glaucoma diagnosis using Spectral Domain OCT and standard automated perimetry.

PubMed

Silva, Fabrício R; Vidotti, Vanessa G; Cremasco, Fernanda; Dias, Marcelo; Gomi, Edson S; Costa, Vital P

2013-01-01

To evaluate the sensitivity and specificity of machine learning classifiers (MLCs) for glaucoma diagnosis using Spectral Domain OCT (SD-OCT) and standard automated perimetry (SAP). Observational cross-sectional study. Sixty two glaucoma patients and 48 healthy individuals were included. All patients underwent a complete ophthalmologic examination, achromatic standard automated perimetry (SAP) and retinal nerve fiber layer (RNFL) imaging with SD-OCT (Cirrus HD-OCT; Carl Zeiss Meditec Inc., Dublin, California). Receiver operating characteristic (ROC) curves were obtained for all SD-OCT parameters and global indices of SAP. Subsequently, the following MLCs were tested using parameters from the SD-OCT and SAP: Bagging (BAG), Naive-Bayes (NB), Multilayer Perceptron (MLP), Radial Basis Function (RBF), Random Forest (RAN), Ensemble Selection (ENS), Classification Tree (CTREE), Ada Boost M1(ADA),Support Vector Machine Linear (SVML) and Support Vector Machine Gaussian (SVMG). Areas under the receiver operating characteristic curves (aROC) obtained for isolated SAP and OCT parameters were compared with MLCs using OCT+SAP data. Combining OCT and SAP data, MLCs' aROCs varied from 0.777(CTREE) to 0.946 (RAN).The best OCT+SAP aROC obtained with RAN (0.946) was significantly larger the best single OCT parameter (p<0.05), but was not significantly different from the aROC obtained with the best single SAP parameter (p=0.19). Machine learning classifiers trained on OCT and SAP data can successfully discriminate between healthy and glaucomatous eyes. The combination of OCT and SAP measurements improved the diagnostic accuracy compared with OCT data alone.

High Expression of Galectin-3 in Patients with IgG4-Related Disease: A Proteomic Approach.

PubMed

Salah, Adeeb; Yoshifuji, Hajime; Ito, Shinji; Kitagori, Koji; Kiso, Kaori; Yamada, Norishige; Nakajima, Toshiki; Haga, Hironori; Tsuruyama, Tatsuaki; Miyagawa-Hayashino, Aya

2017-01-01

Immunoglobulin G4-related disease (IgG4-RD) is a multiorgan condition manifesting itself in different forms. This study aimed to investigate protein expression profiles and to find the possible biomarker for IgG4-RD by liquid chromatography mass spectrometry (LC-MS) using tissue sections in IgG4-RD patients. Protein expression profiles in five IgG4-related pancreatitis and three normal pancreatic samples were compared using LC-MS and were validated by quantitative real-time PCR (qRT-PCR), immunoblotting, and immunohistochemistry. ELISA was employed in the serum of 20 patients with systemic IgG4-RD before and during steroid treatment. LC-MS indicated that the levels of 17 proteins were significantly higher and 12 others were significantly lower in IgG4-related pancreatitis patients compared to controls. Among these proteins, galectin-3 levels were 13-fold higher in IgG4-related pancreatitis ( P < 0.01). These results were confirmed by immunoblotting and qRT-PCR. The average number of galectin-3 + cells in various organs of IgG4-RD patients, including salivary glands, lungs, and lymph nodes, was higher than in controls. Galectin-3 was detectable in macrophages, dendritic cells, and stromal myofibroblast-like cells, but not in lymphocytes by immunofluorescence staining. Serum galectin-3 levels were higher in patients with IgG4-RD compared with healthy donors and remained high during steroid therapy. Galectin-3 was overexpressed in IgG4-RD and the levels were indirectly related to clinical activity.

High Expression of Galectin-3 in Patients with IgG4-Related Disease: A Proteomic Approach

PubMed Central

Salah, Adeeb; Yoshifuji, Hajime; Ito, Shinji; Kitagori, Koji; Kiso, Kaori; Yamada, Norishige; Nakajima, Toshiki; Haga, Hironori; Tsuruyama, Tatsuaki

2017-01-01

Objectives Immunoglobulin G4-related disease (IgG4-RD) is a multiorgan condition manifesting itself in different forms. This study aimed to investigate protein expression profiles and to find the possible biomarker for IgG4-RD by liquid chromatography mass spectrometry (LC-MS) using tissue sections in IgG4-RD patients. Methods Protein expression profiles in five IgG4-related pancreatitis and three normal pancreatic samples were compared using LC-MS and were validated by quantitative real-time PCR (qRT-PCR), immunoblotting, and immunohistochemistry. ELISA was employed in the serum of 20 patients with systemic IgG4-RD before and during steroid treatment. Results LC-MS indicated that the levels of 17 proteins were significantly higher and 12 others were significantly lower in IgG4-related pancreatitis patients compared to controls. Among these proteins, galectin-3 levels were 13-fold higher in IgG4-related pancreatitis (P < 0.01). These results were confirmed by immunoblotting and qRT-PCR. The average number of galectin-3 + cells in various organs of IgG4-RD patients, including salivary glands, lungs, and lymph nodes, was higher than in controls. Galectin-3 was detectable in macrophages, dendritic cells, and stromal myofibroblast-like cells, but not in lymphocytes by immunofluorescence staining. Serum galectin-3 levels were higher in patients with IgG4-RD compared with healthy donors and remained high during steroid therapy. Conclusion Galectin-3 was overexpressed in IgG4-RD and the levels were indirectly related to clinical activity. PMID:28593065

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

PubMed Central

Zhang, Yi; Ng, Huck-Hui; Erdjument-Bromage, Hediye; Tempst, Paul; Bird, Adrian; Reinberg, Danny

1999-01-01

ATP-dependent nucleosome remodeling and core histone acetylation and deacetylation represent mechanisms to alter nucleosome structure. NuRD is a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. The histone deacetylases HDAC1 and HDAC2 and the histone binding proteins RbAp48 and RbAp46 form a core complex shared between NuRD and Sin3-histone deacetylase complexes. The histone deacetylase activity of the core complex is severely compromised. A novel polypeptide highly related to the metastasis-associated protein 1, MTA2, and the methyl-CpG-binding domain-containing protein, MBD3, were found to be subunits of the NuRD complex. MTA2 modulates the enzymatic activity of the histone deacetylase core complex. MBD3 mediates the association of MTA2 with the core histone deacetylase complex. MBD3 does not directly bind methylated DNA but is highly related to MBD2, a polypeptide that binds to methylated DNA and has been reported to possess demethylase activity. MBD2 interacts with the NuRD complex and directs the complex to methylated DNA. NuRD may provide a means of gene silencing by DNA methylation. PMID:10444591

Impact of the river Liffey discharge on nutrient and chlorophyll concentrations in the Liffey estuary and Dublin Bay (Irish Sea)

NASA Astrophysics Data System (ADS)

O'Higgins, T. G.; Wilson, J. G.

2005-08-01

Temperature, salinity, nutrients (total oxidised nitrogen (TON), ammonium (NH 4) and orthophosphate (PO 4)) and chlorophyll a were monitored in the Liffey estuary and Dublin Bay from June 2000 to June 2003. Four groups of sites were defined comprising the upper estuary (Gp. I), the outer estuary (Gp. III) with a small set (Gp. II) of sites between Groups I and III heavily influenced by the sewage treatment works outflow, and the Bay proper (Gp. IV). Riverine inputs of TON and PO 4 were calculated at an average of 826 t N y -1 and 31 t P y -1, respectively, and were largely controlled by flow rate. The sewage treatment works were identified as a major source of PO 4 and NH 4 to the system. Mixing in the upper estuary of nutrient limited saline waters with hypernutrified river water regularly (i.e. annually) produced relatively high concentrations of chlorophyll a (>10 mg chl a m -3), and also sporadic blooms with extremely high chlorophyll a values (max. 121.6 mg chl a m -3). These latter phytoplankton blooms occurred in high salinity waters and were due to mixing of nutrient limited saline waters and nutrient rich river waters. The mean annual flux of phytoplankton carbon from the river Liffey was calculated at 23.5 t C y -1, of which half was accumulated or remineralised in the estuary and did not enter the Bay. In the Bay proper (Gp. IV) summer nutrient concentrations dropped below detection limits, and chlorophyll a concentrations followed the classic pattern with a spring bloom maximum of 5.5 mg chl a m -3. This pattern in nutrients and chlorophyll a came from the advection of waters into the Bay from an offshore source. Overall while there was considerable evidence for eutrophication in the estuary, the bay itself showed little biological response to nutrient loading.

The Rise and Decline of U.S. Private Sector Investments in Energy R&D since the Arab Oil Embargo of 1973

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dooley, James J.

2010-11-01

This paper presents two distinct datasets that describe investments in energy research and development (R&D) by the US private sector since the mid1970s, which is when the US government began to systematically collect these data. The first dataset is based upon a broad survey of more than 20,000 firms’ industrial R&D activities. This broad survey of US industry is coordinated by the US National Science Foundation. The second dataset discussed here is a much narrower accounting of the energy R&D activities of the approximately two dozen largest US oil and gas companies conducted by the US Department of Energy’s Energymore » Information Agency. Even given the large disparity in the breadth and scope of these two surveys of the private sector’s support for energy R&D, both datasets tell the same story in terms of the broad outlines of the private sector’s investments in energy R&D since the mid 1970s. The broad outlines of the US private sector’s support for energy R&D since the mid 1970s is: (1) In the immediate aftermath of the Arab Oil Embargo of 1973, there is a large surge in US private sector investments in energy R&D that peaked in the period between 1980 and 1982 at approximately $3.7 billion to $6.7 billion per year (in inflation adjusted 2010 US dollars) depending upon which survey is used (2) Private sector investments in energy R&D declined from this peak until bottoming out at approximately $1.8 billion to $1 billion per year in 1999; (3) US private sector support for energy R&D has recovered somewhat over the past decade and stands at $2.2 billion to $3.4 billion. Both data sets indicate that the US private sector’s support for energy R&D has been and remains dominated by fossil energy R&D and in particular R&D related to the needs of the oil and gas industry.« less

International Metadata Initiatives: Lessons in Bibliographic Control.

ERIC Educational Resources Information Center

Caplan, Priscilla

This paper looks at a subset of metadata schemes, including the Text Encoding Initiative (TEI) header, the Encoded Archival Description (EAD), the Dublin Core Metadata Element Set (DCMES), and the Visual Resources Association (VRA) Core Categories for visual resources. It examines why they developed as they did, major point of difference from…

A strange cat in Dublin

NASA Astrophysics Data System (ADS)

O'Raifeartaigh, Cormac

2012-11-01

Not many life stories in physics involve Nazis, illicit sex, a strange cat and the genetic code. Thus, a new biography of the great Austrian physicist Erwin Schrödinger is always of interest, and with Erwin Schrödinger and the Quantum Revolution, veteran science writer John Gribbin does not disappoint.

Partnerships To Mine Unexploited Sources of Metadata.

ERIC Educational Resources Information Center

Reynolds, Regina Romano

This paper discusses the metadata created for other purposes as a potential source of bibliographic data. The first section addresses collecting metadata by means of templates, including the Nordic Metadata Project's Dublin Core Metadata Template. The second section considers potential partnerships for re-purposing metadata for bibliographic use,…

The Competitive Struggle.

ERIC Educational Resources Information Center

Barry, Jeff; Bilal, Dania; Penniman, W. David

1998-01-01

Presents results of a survey of 30 library systems vendors to examine how successfully they met the key challenges of 1997: integration, testing, and marketing a new generation of systems. Character-based systems, the Dublin Core, Java, and the Z39.50 standard are discussed. Profiles describing sales and product developments for each of the…

EFFECT OF AIR-POLLUTION CONTROL ON DEATH RATES IN DUBLIN, IRELAND: AN INTERVENTION STUDY. (R827353C006)

EPA Science Inventory

Background Particulate air pollution episodes have been associated with increased daily death. However, there is little direct evidence that diminished particulate air pollution concentrations would lead to reductions in death rates. We assessed the effect of ...

Australian Core Catholic Youth, Catholic Schools and Religious Education

ERIC Educational Resources Information Center

Rymarz, Richard; Graham, John

2006-01-01

This paper reports on research on the attitudes of a differentiated sample of students to Catholic schools in general and religious education in particular. Core Catholic youth are described, following Fulton "et al." (2000: "Young Catholics at the New Millennium", Dublin, University College Press), as individuals who have an…

Studying Abroad Inclusively: Reflections by College Students with and without Intellectual Disability

ERIC Educational Resources Information Center

Prohn, Seb M.; Kelley, Kelly R.; Westling, David L.

2016-01-01

Postsecondary education programs have increased opportunities for students with and without intellectual disabilities to study abroad as inclusive classes. Using open-coding qualitative techniques, the authors examined an inclusive study abroad group's daily reflective journals during a study abroad trip to London and Dublin. Three shared…

Models of Re-Engaging Adult Learners with Mathematics

ERIC Educational Resources Information Center

O'Sullivan, Ciaran; Robinson, Paul; Keogh, John; O'Neill, John

2017-01-01

So-called "Mathematics-anxiety" can be a key inhibitor for some adult learners considering higher education. The Institute of Technology Tallaght (ITT) in Dublin hosts the "Centre of Expertise for Adult Numeracy/Mathematics Education" mathematics research group which is a hub of EPISTEM, formerly known as the "National…

Searchers Net Treasure in Monterey.

ERIC Educational Resources Information Center

McDermott, Irene E.

1999-01-01

Reports on Web keyword searching, metadata, Dublin Core, Extensible Markup Language (XML), metasearch engines (metasearch engines search several Web indexes and/or directories and/or Usenet and/or specific Web sites), and the Year 2000 (Y2K) dilemma, all topics discussed at the second annual Internet Librarian Conference sponsored by Information…

78 FR 53054 - Radio Broadcasting Services; Chillicothe, Dublin, Hillsboro, and Marion, Ohio

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-28

... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [FCC 13-105; MB Docket No. 02-266; RM-10557... Communications Commission. ACTION: Final rule; application for review. SUMMARY: This document denies an... Channel Communications for the reallotment, downgrade in class of channel, and change of community of...

Digital Initiatives and Metadata Use in Thailand

ERIC Educational Resources Information Center

SuKantarat, Wichada

2008-01-01

Purpose: This paper aims to provide information about various digital initiatives in libraries in Thailand and especially use of Dublin Core metadata in cataloguing digitized objects in academic and government digital databases. Design/methodology/approach: The author began researching metadata use in Thailand in 2003 and 2004 while on sabbatical…

George Sigerson: Charcot's translator.

PubMed

Lyons, J B

1997-04-01

Senator George Sigerson (1836-1925), Dublin's first neurologist, was also a significant contributor to Anglo-Irish literature. His medical career and literary accomplishments are outlined, the focus of the article being Sigerson's friendly relationship with Charcot (with whom he corresponded), and whose Leçons sur les maladies du système nerveux he translated.

Wireless Technologies in Support of ISS Experimentation and Operations

NASA Technical Reports Server (NTRS)

Wagner, Raymond; Fink, Patrick

2012-01-01

Presentation reviews: (1) Wireless Communications (a) Internal (b) External (2) RFID (Radio Frequency Identification) (a) Existing and R&D (3) Wireless Sensor Networks (a) Existing and R&D (4) Ultra-Wide Band (UWB) (a) R&D

Are patients referred to rehabilitation diagnosed accurately?

PubMed

Tederko, Piotr; Krasuski, Marek; Nyka, Izabella; Mycielski, Jerzy; Tarnacka, Beata

2017-07-17

An accurate diagnosis of the leading health condition and comorbidities is a prerequisite for safe and effective rehabilitation. The problem of diagnostic errors in physical and rehabilitation medicine (PRM) has not been addressed sufficiently. The responsibility of a referring physician is to determine indications and contraindications for rehabilitation. To assess the rate of and risk factors for inaccurate referral diagnoses (RD) in patients referred to a rehabilitation facility. We hypothesized that inaccurate RD would be more common in patients 1) referred by non-PRM physicians; 2) waiting longer for the admission; 3) older patients. Retrospective observational study. 1000 randomly selected patients admitted between 2012 and 2016 to a day- rehabilitation center (DRC). University DRC specialized in musculoskeletal diseases. On admission all cases underwent clinical verification of RD. Inappropriateness regarding primary diagnoses and comorbidities were noted. Influence of several factors affecting probability of inaccurate RD was analyzed with multiple binary regression model applied to 6 categories of diseases. The rate of inaccurate RD was 25.2%. Higher frequency of inaccurate RD was noted among patients referred by non-PRM specialists (30.3% vs 17.3% in cases referred by PRM specialists). Application of logit regression showed highly significant influence of the specialty of a referring physician on the odds of inaccurate RD (joint Wald test ch2(6)=38.98, p- value=0.000), controlling for the influence of other variables. This may reflect a suboptimal knowledge of the rehabilitation process and a tendency to neglect of comorbidities by non-PRM specialists. The rate of inaccurate RD did not correlate with time between referral and admission (joint Wald test of all odds ratios equal to 1, chi2(6)=5.62, p-value=0.467), however, mean and median waiting times were relatively short (35.7 and 25 days respectively).A high risk of overlooked multimorbidity was revealed in elderly patients (all odds ratios for variable age significantly higher than 1). Hypotheses 1 and 3 were confirmed. Over 25% of patients referred to DRC had inaccurate RD. Risk factors for inaccurate RD include referral by a non-PRM specialist and elderly age. Verification of RD should be routinely introduced to PRM practice.

Diffusion tensor MRI tractography reveals increased fractional anisotropy (FA) in arcuate fasciculus following music-cued motor training.

PubMed

Moore, Emma; Schaefer, Rebecca S; Bastin, Mark E; Roberts, Neil; Overy, Katie

2017-08-01

Auditory cues are frequently used to support movement learning and rehabilitation, but the neural basis of this behavioural effect is not yet clear. We investigated the microstructural neuroplasticity effects of adding musical cues to a motor learning task. We hypothesised that music-cued, left-handed motor training would increase fractional anisotropy (FA) in the contralateral arcuate fasciculus, a fibre tract connecting auditory, pre-motor and motor regions. Thirty right-handed participants were assigned to a motor learning condition either with (Music Group) or without (Control Group) musical cues. Participants completed 20minutes of training three times per week over four weeks. Diffusion tensor MRI and probabilistic neighbourhood tractography identified FA, axial (AD) and radial (RD) diffusivity before and after training. Results revealed that FA increased significantly in the right arcuate fasciculus of the Music group only, as hypothesised, with trends for AD to increase and RD to decrease, a pattern of results consistent with activity-dependent increases in myelination. No significant changes were found in the left ipsilateral arcuate fasciculus of either group. This is the first evidence that adding musical cues to movement learning can induce rapid microstructural change in white matter pathways in adults, with potential implications for therapeutic clinical practice. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

BJUT at TREC 2015 Microblog Track: Real Time Filtering Using Knowledge Base

DTIC Science & Technology

2015-11-20

learning to rank of tweets. In Proceedings of the 23rd International Conference on Computational Linguistics , pages 295–303. Association for Computational... Linguistics , 2010. Thorsten Joachims. Optimizing search engines using clickthrough data. In Proceedings of the eighth ACM SIGKDD international

Plantar pressure distribution of ostrich during locomotion on loose sand and solid ground

PubMed Central

Han, Dianlei; Ma, Songsong; Luo, Gang; Ji, Qiaoli; Xue, Shuliang; Yang, Mingming; Li, Jianqiao

2017-01-01

Background The ostrich is a cursorial bird with extraordinary speed and endurance, especially in the desert, and thus is an ideal large-scale animal model for mechanic study of locomotion on granular substrate. Methods The plantar pressure distributions of ostriches walking/running on loose sand/solid ground were recorded using a dynamic pressure plate. Results The center of pressure (COP) on loose sand mostly originated from the middle of the 3rd toe, which differed from the J-shaped COP trajectory on solid ground. At mid-stance, a high-pressure region was observed in the middle of the 3rd toe on loose sand, but three high-pressure regions were found on solid ground. The gait mode significantly affected the peak pressures of the 3rd and 4th toes (p = 1.5 × 10−6 and 2.39 × 10−8, respectively), but not that of the claw (p = 0.041). The effects of substrate were similar to those of the gait mode. Discussion Ground reaction force trials of each functional part showed the 3rd toe bore more body loads and the 4th toe undertook less loads. The pressure distributions suggest balance maintenance on loose sand was provided by the 3rd and 4th toes and the angle between their length axes. On loose sand, the middle of the 3rd toe was the first to touch the sand with a smaller attack angle to maximize the ground reaction force, but on solid ground, the lateral part was the first to touch the ground to minimize the transient loading. At push-off, the ostrich used solidification properties of granular sand under the compression of the 3rd toe to generate sufficient traction. PMID:28761792

The Power of PreK-3rd: How a Small Foundation Helped Push Washington State to the Forefront of the PreK-3rd Movement. FCD Case Study

ERIC Educational Resources Information Center

Nyhan, Paul

2011-01-01

The New School Foundation was not born from a commission, legislative mandate, research project, think tank, or even the mind of a leading education scholar. One of Washington state's pioneering PreK-3rd initiatives began as the brainchild of a wealthy Seattle businessman, Stuart Sloan, 20 years ago. The New School Foundation and its ideas were…

Sickness absence and disability pension following breast cancer - A population-based matched cohort study.

PubMed

Lundh, Marie Høyer; Lampic, Claudia; Nordin, Karin; Ahlgren, Johan; Bergkvist, Leif; Lambe, Mats; Berglund, Anders; Johansson, Birgitta

2014-12-01

To compare sickness absence and disability pension in a population-based cohort of women with breast cancer (n = 463) from 1 year pre-diagnosis until 3 years post-diagnosis with a matched control group (n = 2310), and to investigate predictors of sickness absence during the 2nd and 3rd year post-diagnosis. Following breast cancer, the proportion of disease-free women with sickness absence decreased post-diagnosis (1st-3rd year; 78%-31%-19%), but did not reach the pre-diagnostic level (14%; P < 0.05). Post-diagnosis, patients were more likely than controls to be sickness absent (1st-3rd year; P < 0.001). No between-group differences were observed for disability pension post-diagnosis (P > 0.05). Among patients, chemotherapy, baseline fatigue and pre-diagnosis sick days predicted sickness absence during the 2nd, 3rd, and 2nd and 3rd year post-diagnosis, respectively (P < 0.05). Breast cancer is associated with increased sickness absence 3 years post-diagnosis. In a clinical setting, prevention and treatment of side effects are important in reducing long-term consequences. Copyright © 2014 Elsevier Ltd. All rights reserved.

Characteristics of Internal Medicine Physicians Disciplined by Professional Colleges in Canada.

PubMed

Liu, Jessica J; Alam, Asim Q; Goldberg, Hanna R; Matelski, John Justin; Bell, Chaim M

2015-07-01

Physician misconduct is of serious concern to patient safety and quality of care. Currently, there are limited data on disciplinary proceedings involving internal medicine (IM) physicians.The aim of this study was to investigate the number and nature of disciplinary cases among IM physicians compared with those of other disciplined physicians.Our retrospective study reviewed information from all provincial Colleges of Physicians and Surgeons (CPS) and compiled a database of all disciplined physicians from 2000 to 2013 in Canada. Disciplinary rate differences (RDs) were calculated for IM physicians and compared with other physicians.From 2000 to 2013, overall disciplinary rates were low (9.6 cases per 10,000 physician years). There were 899 disciplinary cases, 49 of which involved 45 different IM physicians. IM physicians comprised 10.8% of all disciplined physicians and were disciplined at a lower rate than non-IM physicians, incurring 5.18 fewer cases per 10,000 physician years than other physicians (95% confidence interval [CI] 3.62-6.73; P < 0.001). They were significantly less likely to be disciplined for: unprofessional conduct (RD 1.16; CI 0.45-1.87; P = 0.001); unlicensed activity (RD 0.78; CI 0.37-1.19; P < 0.001); standard of care issues (RD 1.37; CI 0.49-2.26; P = 0.002); sexual misconduct (RD 1.65; CI 0.90-2.40; P < 0.001); miscellaneous (RD 0.80; CI 0.11-1.50; P = 0.020); mental illness (RD 0.06; CI 0.01-0.12; P = 0.025); inappropriate prescribing (RD 0.74; CI 0.15-1.33; P = 0.010); and criminal conviction (RD 0.33; CI 0.00-0.65; P = 0.048). No significant differences were found with respect to unclear violations, fraudulent behavior/prevarication, or offenses involving drugs/alcohol (all RDs less than 0.32). IM physicians were also less likely to incur the following penalties: voluntary license surrender (RD 0.53; CI 0.37-0.69; P < 0.001); suspension (RD 2.39; CI 1.26-3.51; P < 0.001); retraining/assessment (RD 1.58; CI 0.77-2.39; P < 0.001); restriction (RD 1.60; CI 0.74-2.46; P < 0.001); other (RD 0.52; CI 0.07-0.97; P = 0.030); formal reprimand (RD 2.78; CI 1.77-3.79; P < 0.001); or fine (RD 3.28; CI 1.89-4.67; P < 0.001). No significant differences were found with respect to revocation or mandated counseling/rehabilitation (all RDs less than 0.46).Generally, disciplinary rates among physicians were low. Compared with other physicians, IM physicians have significantly lower disciplinary rates overall and are less likely to incur the majority of disciplinary offenses and penalties.

WNN 92; Proceedings of the 3rd Workshop on Neural Networks: Academic/Industrial/NASA/Defense, Auburn Univ., AL, Feb. 10-12, 1992 and South Shore Harbour, TX, Nov. 4-6, 1992

NASA Technical Reports Server (NTRS)

Padgett, Mary L. (Editor)

1993-01-01

The present conference discusses such neural networks (NN) related topics as their current development status, NN architectures, NN learning rules, NN optimization methods, NN temporal models, NN control methods, NN pattern recognition systems and applications, biological and biomedical applications of NNs, VLSI design techniques for NNs, NN systems simulation, fuzzy logic, and genetic algorithms. Attention is given to missileborne integrated NNs, adaptive-mixture NNs, implementable learning rules, an NN simulator for travelling salesman problem solutions, similarity-based forecasting, NN control of hypersonic aircraft takeoff, NN control of the Space Shuttle Arm, an adaptive NN robot manipulator controller, a synthetic approach to digital filtering, NNs for speech analysis, adaptive spline networks, an anticipatory fuzzy logic controller, and encoding operations for fuzzy associative memories.

Sentinel-1 SAR Deployment Testing- Lessons Learned

NASA Astrophysics Data System (ADS)

Schwarz, Sebastian; Alberti, Mathias V.

2015-09-01

On April 3rd 2014, ESA has launched the Sentinel-1A spacecraft with its SAR instrument payload. During the first 12 hours in space, the antenna was released and successfully deployed to its operational configuration. Almost 6 years before that date, the first conceptual considerations regarding integration, alignment and on- ground deployment testing took place. Starting in these early phases of the project, the paper contains an overview of the concepts and trades which were performed to identify the most suitable off-loading MGSE for this heavy and fragile antenna. Following that, the challenges and lessons learned during the different developments of this test setup are discussed. This includes MGSE specific topics, such as the minimization of structural deformation under load or the optimization of the pulley arrangement as result of a coupled multibody analysis. On the other hand, load and deformation control strategies for the flight hardware, as well as safety related aspects are covered.

The regulatory element READ1 epistatically influences reading and language, with both deleterious and protective alleles

PubMed Central

Powers, Natalie R; Eicher, John D; Miller, Laura L; Kong, Yong; Smith, Shelley D; Pennington, Bruce F; Willcutt, Erik G; Olson, Richard K; Ring, Susan M; Gruen, Jeffrey R

2016-01-01

Background Reading disability (RD) and language impairment (LI) are heritable learning disabilities that obstruct acquisition and use of written and spoken language, respectively. We previously reported that two risk haplotypes, each in strong linkage disequilibrium (LD) with an allele of READ1, a polymorphic compound short tandem repeat within intron 2 of risk gene DCDC2, are associated with RD and LI. Additionally, we showed a non-additive genetic interaction between READ1 and KIAHap, a previously reported risk haplotype in risk gene KIAA0319, and that READ1 binds the transcriptional regulator ETV6. Objective To examine the hypothesis that READ1 is a transcriptional regulator of KIAA0319. Methods We characterised associations between READ1 alleles and RD and LI in a large European cohort, and also assessed interactions between READ1 and KIAHap and their effect on performance on measures of reading, language and IQ. We also used family-based data to characterise the genetic interaction, and chromatin conformation capture (3C) to investigate the possibility of a physical interaction between READ1 and KIAHap. Results and conclusions READ1 and KIAHap show interdependence—READ1 risk alleles synergise with KIAHap, whereas READ1 protective alleles act epistatically to negate the effects of KIAHap. The family data suggest that these variants interact in trans genetically, while the 3C results show that a region of DCDC2 containing READ1 interacts physically with the region upstream of KIAA0319. These data support a model in which READ1 regulates KIAA0319 expression through KIAHap and in which the additive effects of READ1 and KIAHap alleles are responsible for the trans genetic interaction. PMID:26660103

Endoventricular Deep Brain Stimulation of the Third Ventricle: Proof of Concept and Application to Cluster Headache.

PubMed

Chabardès, Stéphan; Carron, Romain; Seigneuret, Eric; Torres, Napoleon; Goetz, Laurent; Krainik, Alexandre; Piallat, Brigitte; Pham, Pascale; David, Olivier; Giraud, Pierrick; Benabid, Alim Louis

2016-12-01

The third ventricle (3rd V) is surrounded by centers related to satiety, homeostasis, hormones, sleep, memory, and pain. Stimulation of the wall of the 3rd V could be useful to treat disorders related to dysfunction of the hypothalamus. To assess safety and efficacy of endoventricular electrical stimulation of the hypothalamus using a floating deep brain stimulation (DBS) lead laid on the floor of the 3rd V to treat refractory cluster headaches (CH). Seven patients, aged 24 to 60 years, experiencing chronic CH (mean chronic duration 5.8 ± 2.5 years) were enrolled in this pilot, prospective, open study assessing the safety and potential efficacy of chronic DBS of the 3rd V. Number of attacks was collected during baseline and was compared with those occurring at 3, 6, and 12 months postoperation. Any side effects that occurred during or after surgery were reported. Effect on mood was assessed using the Hospital Anxiety and Depression scale during baseline and at 6 and 12 months postoperation. Insertion of the lead into the posterior 3rd V and chronic stimulation was feasible and safe in all patients. The voltage ranged from 0.9 to 2.3 volts. The most common side effect was transient trembling vision during stimulation. At 12 months, 3 of 7 patients were pain free, 2 had 90% improvement, 1 of 7 had 75% improvement, and 1 of 7 was not significantly improved. This proof of concept demonstrates the feasibility, safety, and potential efficacy of 3rd V DBS using an endoventricular road that could be applied to treat various diseases involving hypothalamic areas. CCH, chronic cluster headacheCH, cluster headacheDBS, deep brain stimulationHAD, hospital anxiety depressionONS, occipital nerve stimulationPAG, periaqueductal gray matterPH, posterior hypothalamusPVG, periventricular gray matter3rd V, third ventricle.

The role of IL-6 and IL-1beta in painful perineural inflammatory neuritis.

PubMed

Eliav, Eli; Benoliel, Rafael; Herzberg, Uri; Kalladka, Mythili; Tal, Michael

2009-05-01

Inflammation along a nerve trunk (perineural inflammation), without detectable axonal damage, has been shown to induce transient pain in the organ supplied by the nerve. The aims of the present study were to study the role IL-6 and IL-1beta, in pain induced by perineural inflammation. IL-6 and IL-1beta secretion from rat's sciatic nerves, L-5 Dorsal Root Ganglia (DRG), and the hind paw skin, 3 and 8 days following exposure of the nerve to Complete Freund's Adjuvant (CFA), were measured using ELISA method. Hind paw tactile-allodynia, mechano-hyperalgesia, heat-allodynia and electrical detection thresholds were tested up to 8 days following the application of CFA, IL-6 or IL-1beta adjacent to the sciatic nerve trunk. Employing electrophysiological recording, saphenous nerve spontaneous activity, nerve trunk mechano-sensitivity and paw tactile detection threshold (determined by recording action potential induced by the lowest mechanical stimulus) were assessed 3 and 8 days following exposure of the nerve trunk to CFA, IL-6, or IL-1beta. IL-6 and IL-1beta secretion from the nerve was significantly elevated on the 3rd day post-operation (DPO). On the 8th DPO, IL-6 levels returned to baseline while IL-1beta levels remained significantly elevated. The DRG cytokine's level was increased on the 3rd and 8th DPOs, contralateral cytokine's level was increased on the 3rd DPO. The skin IL-6 level was increased bilaterally on the 3rd DPO and returned to baseline on the 8th DPO. IL-1beta levels increased in the affected side on the 3rd and bilaterally on the 8th DPO. Direct application of IL-6 or CFA on the sciatic nerve induced significant hind paw tactile-allodynia from the 1st to 5th DPOs, reduced electrical detection threshold from the 1st to 3rd DPOs, mechano-hyperalgesia from 3rd to 5th DPOs and heat-allodynia on the 3rd DPO. Direct application of IL-1beta induced paw tactile and heat-allodynia on the 7-8th DPOs and mechano-hyperalgesia on the 5-8th DPOs. Perineural inflammation significantly increased spontaneous activity myelinated fibres 3 and 8 days following the application. Direct application of IL-6 induced elevation of spontaneous activity on the 3rd while IL-1beta on the 8th DPO. Nerve mechano-sensitivity was significantly increased on the 3rd day following exposure to CFA and IL-6 and on the 8th following CFA application. The rat's paw lowest mechanical force necessary for induction of action potential, was significantly reduced 3 days following CFA application. IL-6 and IL-1beta play an important role in pain induced by perineural inflammation. IL-6 activity is more prominent immediately following application (2-5th DPOs), while IL-1beta, activity is more significant in a later stage (5-8th DPOs).

Reduction of wound infections in laparoscopic-assisted colorectal resections by plastic wound ring drapes (REDWIL)?--A randomized controlled trial.

PubMed

Lauscher, J C; Grittner, F; Stroux, A; Zimmermann, M; le Claire, M; Buhr, H J; Ritz, J P

2012-10-01

Surgical site infections (SSIs) are frequent complications in colorectal surgery and may lead to burst abdomen, incisional hernia, and increased perioperative costs. Plastic wound ring drapes (RD) were introduced some decades ago to protect the abdominal wound from bacteria and reduce SSIs. There have been no controlled trials examining the benefit of RD in laparoscopic colorectal surgery. The Reduction of wound infections in laparoscopic assisted colorectal resections by plastic wound ring drapes (REDWIL) trial was thus designed to assess their effectiveness in preventing SSIs after elective laparoscopic colorectal resections. REDWIL is a randomized controlled monocenter trial with two parallel groups (experimental group with RD and control group without RD). Patients undergoing elective laparoscopic colorectal resection were included. The primary endpoint was SSIs. Secondary outcomes were colonization of the abdominal wall with bacteria, reoperations/readmissions, early/late postoperative complications, and cost of hospital stay. The duration of follow-up was 6 months. Between January 2008 and October 2010, 109 patients were randomly assigned to the experimental or control group (with or without RD). Forty-six patients in the RD group and 47 patients in the control group completed follow-up. SSIs developed in ten patients with RD (21.7 %) and six patients without RD (12.8 %) (p = 0.28). An intraoperative swab taken from the abdominal wall was positive in 66.7 % of patients with RD and 57.5 % without RD (p = 0.46). The number of species cultured within one swab was significantly higher in those without RD (p = 0.03). The median total inpatient costs including emergency readmissions were 3,402 ± 4,038 in the RD group and 3,563 ± 1,735 in the control group (p = 0.869). RD do not reduce the rate of SSIs in laparoscopic colorectal surgery. The inpatient costs are similar with and without RD.

Discover the pythagorean theorem using interactive multimedia learning

NASA Astrophysics Data System (ADS)

Adhitama, I.; Sujadi, I.; Pramudya, I.

2018-04-01

In learning process students are required to play an active role in learning. They do not just accept the concept directly from teachers, but also build their own knowledge so that the learning process becomes more meaningful. Based on the observation, when learning Pythagorean theorem, students got difficulty on determining hypotenuse. One of the solution to solve this problem is using an interactive multimedia learning. This article aims to discuss the interactive multimedia as learning media for students. This was a Research and Development (R&D) by using ADDIE model of development. The results obtained was multimedia which was developed proper for students as learning media. Besides, on Phytagorian theorem learning activity we also compare Discovery Learning (DL) model with interactive multimedia and DL without interactive multimedia, and obtained that DL with interactive gave positive effect better than DL without interactive multimedia. It was also obtainde that interactive multimedia can attract and increase the interest ot the students on learning math. Therefore, the use of interactive multimedia on DL procees can improve student learning achievement.

Pharmacokinetic properties of tandem d-peptides designed for treatment of Alzheimer's disease.

PubMed

Leithold, Leonie H E; Jiang, Nan; Post, Julia; Niemietz, Nicole; Schartmann, Elena; Ziehm, Tamar; Kutzsche, Janine; Shah, N Jon; Breitkreutz, Jörg; Langen, Karl-Josef; Willuweit, Antje; Willbold, Dieter

2016-06-30

Peptides are more and more considered for the development of drug candidates. However, they frequently exhibit severe disadvantages such as instability and unfavourable pharmacokinetic properties. Many peptides are rapidly cleared from the organism and oral bioavailabilities as well as in vivo half-lives often remain low. In contrast, some peptides consisting solely of d-enantiomeric amino acid residues were shown to combine promising therapeutic properties with high proteolytic stability and enhanced pharmacokinetic parameters. Recently, we have shown that D3 and RD2 have highly advantageous pharmacokinetic properties. Especially D3 has already proven promising properties suitable for treatment of Alzheimer's disease. Here, we analyse the pharmacokinetic profiles of D3D3 and RD2D3, which are head-to-tail tandem d-peptides built of D3 and its derivative RD2. Both D3D3 and RD2D3 show proteolytic stability in mouse plasma and organ homogenates for at least 24h and in murine and human liver microsomes for 4h. Notwithstanding their high affinity to plasma proteins, both peptides are taken up into the brain following i.v. as well as i.p. administration. Although both peptides contain identical d-amino acid residues, they are arranged in a different sequence order and the peptides show differences in pharmacokinetic properties. After i.p. administration RD2D3 exhibits lower plasma clearance and higher bioavailability than D3D3. We therefore concluded that the amino acid sequence of RD2 leads to more favourable pharmacokinetic properties within the tandem peptide, which underlines the importance of particular sequence motifs, even in short peptides, for the design of further therapeutic d-peptides. Copyright © 2016 Elsevier B.V. All rights reserved.

Research and development in drug innovation: reflections from the 2013 bioeconomy conference in China, lessons learned and future perspectives

PubMed Central

Liu, Changxiao; Constantinides, Panayiotis P.; Li, Yazhuo

2014-01-01

The enormous progress biotechnology, bioinformatics and nanotechnology made in recent years provides opportunities and scientific framework for development of biomedicine and constitutes a paradigm shift in pharmaceutical R&D and drug innovation. By analyzing the data and related information at R&D level over the past decades, developmental tendency and R&D patterns were summarized. We found that a growing number of biologics in the pipeline of pharma companies with successful products already in the market though, small molecular entities have primarily dominated drug innovation. Additionally, small/medium size companies will continue to play a key role in the development of small molecule drugs and biologics in a multi-channel integrated process. More importantly, modern and effective R&D strategies in biomedicine development to predict and evaluate efficacy and/or safety of 21st century therapeutics are urgently needed. To face new challenges, developmental strategies were proposed, in terms of molecular targeted medicine, generic drugs, new drug delivery system and protein-based drugs. Under the current circumstances, interdisciplinary cooperation mode and policy related to drug innovation in China were deeply discussed as well. PMID:26579372

[The influence of phychological features and learning styles on the academic performance of medical students].

PubMed

Bitran, Marcela; Lafuente, Montserrat; Zúñiga, Denisse; Viviani, Paola; Mena, Beltrán

2004-09-01

The degree of difficulty we experience while learning different concepts and skills depends, among other things, on our psychological features and learning style. This may be particularly true for medical students, whose formation involves the acquisition of multiple cognitive, affective and psychomotor skills. To assess whether the psychological features and learning styles of medical students are associated with their academic performance. The psychological preferences and learning styles of 66 students of the 2001-graduating cohort were determined with the Myers Briggs Type Inventory (MBTI) and the Kolb Learning Style Inventory (LSI), respectively. The academic performance was assessed by the Calificación Médica Nacional (CMN), Chile and by the marks obtained during the Basic (1st to 3rd), Preclinical (4th and 5th) and Clinical (6th and 7th) years of undergraduate training. The psychological features, together with the sex of students were found to be associated with the performance in the Preclinical and Clinical years, and to the CMN. In men, the interest and ability to communicate with people and the concern for harmony, and in women the tendency to function in a systematic and orderly way are the features associated to high academic performance. No associations were found between learning styles and academic performance. The finding that the psychological preferences of medical students are relevent to their academic performance opens a new perspective to analyze the medical education and to design programs aimed at improving learning.

A foreign body in disguise.

PubMed

Leith, R; O'Connell, A C

2013-10-01

Young children habitually place objects in their mouths to discover and learn about the world and it is considered a normal stage of early childhood development. Ingestion and aspiration of foreign objects predominantly occurs in preschool toddlers with a peak incidence at age three years, and can have serious consequences. A 2-year-old boy presented to the Dublin Dental University Hospital with a tooth-coloured mass tightly adherent to a lower primary incisor. The lesion surrounded the cervical third of the crown on the lower right primary central incisor and extended subgingivally. The tooth was mobile but with minimal inflammation. The tooth was subsequently extracted under general anaesthesia to reveal that the mass was in fact a foreign body, although this was originally thought unlikely as a cause. The patient underwent an unremarkable recovery. The case of a foreign body disguised as a tooth-like abnormality was only identified under general anaesthesia, and even then it was impossible to prise the object from the tooth in situ. Misdiagnosis of impacted foreign bodies in young children presents complicated diagnostic problems.

Better management of Irish hospitals.

PubMed

Brugha, C M

1991-08-01

The establishment of the Dublin Hospitals Initiative and the Efficiency Review Group as first steps in an "action" plan was based on the report in 1989 of the Commission of Health Funding which suggested that "the solution to the problem facing the Irish health services...(lies) primarily...in the way that services are planned, organised and delivered". Our health service is in transition from the phase of facility management into that of functional management. This will involve facing the fact of the limit on resources, introducing information systems and getting the co-operation of hospital doctors. The most senior executive in a hospital must firstly be a good general manager with sufficient power to manage. Hospitals should be divided into centres of responsibility made up of one or more centres of activity. Formal education for hospital administrators should be extended. There is a need for training at all levels, particularly of those administrative and medical staff who have direct interaction with the computer-based system. There should be a commitment to management development particularly by means of teamwork and action learning.

RD2-MolPack-Chim3, a packaging cell line for stable production of lentiviral vectors for anti-HIV gene therapy.

PubMed

Stornaiuolo, Anna; Piovani, Bianca Maria; Bossi, Sergio; Zucchelli, Eleonora; Corna, Stefano; Salvatori, Francesca; Mavilio, Fulvio; Bordignon, Claudio; Rizzardi, Gian Paolo; Bovolenta, Chiara

2013-08-01

Over the last two decades, several attempts to generate packaging cells for lentiviral vectors (LV) have been made. Despite different technologies, no packaging clone is currently employed in clinical trials. We developed a new strategy for LV stable production based on the HEK-293T progenitor cells; the sequential insertion of the viral genes by integrating vectors; the constitutive expression of the viral components; and the RD114-TR envelope pseudotyping. We generated the intermediate clone PK-7 expressing constitutively gag/pol and rev genes and, by adding tat and rd114-tr genes, the stable packaging cell line RD2-MolPack, which can produce LV carrying any transfer vector (TV). Finally, we obtained the RD2-MolPack-Chim3 producer clone by transducing RD2-MolPack cells with the TV expressing the anti-HIV transgene Chim3. Remarkably, RD114-TR pseudovirions have much higher potency when produced by stable compared with transient technology. Most importantly, comparable transduction efficiency in hematopoietic stem cells (HSC) is obtained with 2-logs less physical particles respect to VSV-G pseudovirions produced by transient transfection. Altogether, RD2-MolPack technology should be considered a valid option for large-scale production of LV to be used in gene therapy protocols employing HSC, resulting in the possibility of downsizing the manufacturing scale by about 10-fold in respect to transient technology.

The proto-oncoprotein FBI-1 interacts with MBD3 to recruit the Mi-2/NuRD-HDAC complex and BCoR and to silence p21WAF/CDKN1A by DNA methylation

PubMed Central

Choi, Won-Il; Jeon, Bu-Nam; Yoon, Jae-Hyeon; Koh, Dong-In; Kim, Myung-Hwa; Yu, Mi-Young; Lee, Kyung-Mi; Kim, Youngsoo; Kim, Kyunggon; Hur, Sujin Susanne; Lee, Choong-Eun; Kim, Kyung-Sup; Hur, Man-Wook

2013-01-01

The tumour-suppressor gene CDKN1A (encoding p21Waf/Cip1) is thought to be epigenetically repressed in cancer cells. FBI-1 (ZBTB7A) is a proto-oncogenic transcription factor repressing the alternative reading frame and p21WAF/CDKN1A genes of the p53 pathway. FBI-1 interacts directly with MBD3 (methyl-CpG–binding domain protein 3) in the nucleus. We demonstrated that FBI-1 binds both non-methylated and methylated DNA and that MBD3 is recruited to the CDKN1A promoter through its interaction with FBI-1, where it enhances transcriptional repression by FBI-1. FBI-1 also interacts with the co-repressors nuclear receptor corepressor (NCoR), silencing mediator for retinoid and thyroid receptors (SMRT) and BCL-6 corepressor (BCoR) to repress transcription. MBD3 regulates a molecular interaction between the co-repressor and FBI-1. MBD3 decreases the interaction between FBI-1 and NCoR/SMRT but increases the interaction between FBI-1 and BCoR. Because MBD3 is a subunit of the Mi-2 autoantigen (Mi-2)/nucleosome remodelling and histone deacetylase (NuRD)-HDAC complex, FBI-1 recruits the Mi-2/NuRD-HDAC complex via MBD3. BCoR interacts with the Mi-2/NuRD-HDAC complex, DNMTs and HP1. MBD3 and BCoR play a significant role in the recruitment of the Mi-2/NuRD-HDAC complex– and the NuRD complex–associated proteins, DNMTs and HP. By recruiting DNMTs and HP1, Mi-2/NuRD-HDAC complex appears to play key roles in epigenetic repression of CDKN1A by DNA methylation. PMID:23658227

The effects of an online basic life support course on undergraduate nursing students’ learning

PubMed Central

Tobase, Lucia; Peres, Heloisa H.C.; Smith, Nicole; Polastri, Thatiane F.; Timerman, Sergio

2017-01-01

Objectives To describe learning outcomes of undergraduate nursing students following an online basic life support course (BLS). Methods An online BLS course was developed and administered to 94 nursing students. Pre- and post-tests were used to assess theoretical learning. Checklist simulations and feedback devices were used to assess the cardiopulmonary resuscitation (CPR) skills of the 62 students who completed the course. Results A paired t-test revealed a significant increase in learning [pre-test (6.4 ± 1.61), post-test (9.3 ± 0.82), p < 0.001]. The increase in the average grade after taking the online course was significant (p<0.001). No learning differences (p=0.475) had been observed between 1st and 2nd year (9.20 ± 1.60), and between 3rd and 4th year (9.67 ± 0.61) students. A CPR simulation was performed after completing the course: students checked for a response (90%), exposed the chest (98%), checked for breathing (97%), called emergency services (76%), requested for a defibrillator (92%), checked for a pulse (77%), positioned their hands properly (87%), performed 30 compressions/cycle (95%), performed compressions of at least 5 cm depth (89%), released the chest (90%), applied two breaths (97%), used the automated external defibrillator (97%), and positioned the pads (100%). Conclusions The online course was an effective method for teaching and learning key BLS skills wherein students were able to accurately apply BLS procedures during the CPR simulation. This short-term online training, which likely improves learning and self-efficacy in BLS providers, can be used for the continuing education of health professionals. PMID:28850944

Students' perception of the learning environment in a distributed medical programme.

PubMed

Veerapen, Kiran; McAleer, Sean

2010-09-24

The learning environment of a medical school has a significant impact on students' achievements and learning outcomes. The importance of equitable learning environments across programme sites is implicit in distributed undergraduate medical programmes being developed and implemented. To study the learning environment and its equity across two classes and three geographically separate sites of a distributed medical programme at the University of British Columbia Medical School that commenced in 2004. The validated Dundee Ready Educational Environment Survey was sent to all students in their 2nd and 3rd year (classes graduating in 2009 and 2008) of the programme. The domains of the learning environment surveyed were: students' perceptions of learning, students' perceptions of teachers, students' academic self-perceptions, students' perceptions of the atmosphere, and students' social self-perceptions. Mean scores, frequency distribution of responses, and inter- and intrasite differences were calculated. The perception of the global learning environment at all sites was more positive than negative. It was characterised by a strongly positive perception of teachers. The work load and emphasis on factual learning were perceived negatively. Intersite differences within domains of the learning environment were more evident in the pioneer class (2008) of the programme. Intersite differences consistent across classes were largely related to on-site support for students. Shared strengths and weaknesses in the learning environment at UBC sites were evident in areas that were managed by the parent institution, such as the attributes of shared faculty and curriculum. A greater divergence in the perception of the learning environment was found in domains dependent on local arrangements and social factors that are less amenable to central regulation. This study underlines the need for ongoing comparative evaluation of the learning environment at the distributed sites and interaction between leaders of these sites.