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Sample records for lentes tecnis z-9000

  1. Imaging quality of bifocal piggyback intraocular lens versus ReSTOR and TECNIS multifocal lenses.

    PubMed

    Artigas, José M; Felipe, Adelina; Diaz-Llopis, Manuel; Garcia-Delpech, Salvador; Navea, Amparo

    2010-01-01

    The imaging quality provided by a piggyback integrated by a monofocal intraocular lens (IOL) + a bifocal IOL of zero power and +3.75 diopters of addition is compared with the optics quality of a simple multifocal IOL of the same power and addition. The imaging quality was evaluated by determining the modulation transfer function (MTF), using an artificial eye simulating in vivo conditions of the anterior chamber, including an artificial cornea and a wet cell containing physiologic solution where the IOL was positioned. The MTFs of the bifocal piggyback for near and distance vision were measured, with pupil diameters of 3 and 5 mm, and compared with the MTFs of an equivalent power of ReSTOR and TECNIS multifocal IOLs measured under the same conditions. The MTFs for distance and near focus of the bifocal piggyback are similar to the MTFs of the ReSTOR and TECNIS multifocal IOLs with the two diameters of pupil. A more accurate comparison, values of average modulation, and Strehl ratio show a greater similitude with ReSTOR than with TECNIS. The bifocal piggyback system provides a similar imaging quality to that obtained with a ReSTOR multifocal IOL and, like the ReSTOR, provides better performance in distance vision than in near vision, whereas the TECNIS multifocal IOL provides the best performance.

  2. Primary piggyback implantation using the Tecnis ZM900 multifocal intraocular lens: case series.

    PubMed

    Akaishi, Leonardo; Tzelikis, Patrick F; Gondim, Joyce; Vaz, Rodrigo

    2007-12-01

    To assess the postoperative outcomes of primary piggyback implantation using the Tecnis ZM900 multifocal intraocular lens (IOL) (Advanced Medical Optics). Hospital Oftalmológico de Brasília, Brasília, Brazil. Patients who had phacoemulsification with primary piggyback IOL implantation were analyzed prospectively. In all cases, a Tecnis ZM900 multifocal IOL was implanted in the capsular bag and a second silicone IOL was implanted in the ciliary sulcus. Information collected included near and distance uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), and the spherical equivalent (SE) before and after the surgery. Twenty eyes of 12 patients were included in the study. They were followed for 6 months. The mean preoperative distance UCVA was 20/400. At the last follow-up (6 months), the mean distance UCVA was 20/29, significantly better than before referral (P<.001). The mean preoperative SE was +6.35 diopters (D) +/- 2.25 (SD). Six months after surgery, the mean SE was -0.25 +/- 0.40 D (range -1.00 to +0.50 D), significantly better than before referral (P<.001). No patient lost lines of BCVA after surgery. At the last follow-up, 90% of the eyes achieved a near UCVA of J1 and 83.3% of patients were spectacle independent for near and distance vision. A second refractive procedure was performed in 2 eyes. Primary piggyback implantation using the Tecnis ZM900 multifocal IOL was a simple, safe, and accurate option for patients with high hyperopia who wanted to reduce their dependency on spectacles.

  3. Clinical outcomes after cataract surgery with implantation of the Tecnis ZMB00 multifocal intraocular lens

    PubMed Central

    Lubiński, Wojciech; Gronkowska-Serafin, Jolanta; Podborączyńska-Jodko, Karolina

    2014-01-01

    Background The aim of this study was to evaluate visual performance, contrast sensitivity, and patient satisfaction in patients undergoing cataract surgery with bilateral implantation of the Tecnis ZMB00 diffractive multifocal IOL (intraocular lens). Material/Methods This was a prospective study of 40 eyes of 20 patients with an age range from 48 to 67 years and undergoing cataract surgery with implantation of the diffractive 1-piece IOL Tecnis ZMB00 (Abbott Medical Optics) in 1 eye and 3 weeks later in the other eye. The following parameters were evaluated at 3 and 6 months after the operation: binocular uncorrected distance, intermediate and near visual acuity (UDVA, UIVA, UNVA), uncorrected binocular photopic and mesopic distance and photopic near contrast sensitivity (CSV-1000), subjective symptoms, and patient satisfaction (VF-14). Results No significant change was observed in logMAR UDVA between 3 and 6 months postoperatively (−0.11±0.14 vs. −0.10±0.13, p>0.05). In contrast, UNVA (0.06±0.12 vs. −0.02±0.12, p=0.004) and UIVA (0.12±0.15 vs. 0.07±0.11, p=0.005) in this period improved significantly. At 3 and 6 months after surgery, 85% of patients no longer needed to wear corrective lenses. Contrast sensitivity under different conditions was within normal age-matched limits, with significant improvements for some spatial frequencies at 3 and 6 months after surgery (p<0.04). Mean overall patient satisfaction was 9.39±1.06 and 9.19±1.20 (scale from 1 to 10, with 10 being the best score) at 3 and 6 months, respectively. Low level of halo perception was reported in 75% of patients. Conclusions The Tecnis ZMB00 IOL provides an effective restoration of the distance, intermediate, and near visual function, allowing patients to be totally free of need to wear corrective lenses and providing high levels of patient satisfaction. PMID:25022700

  4. Refractive lens exchange with the diffractive multifocal Tecnis ZM900 intraocular lens.

    PubMed

    Goes, Frank Joseph

    2008-03-01

    To assess visual outcomes and patient satisfaction after refractive lens exchange followed by bilateral implantation of the multifocal Tecnis intraocular lens (IOL). This prospective case series involved 59 eyes of 30 patients aged 56 +/- 8 years. Fifty-seven eyes were hyperopic (+3.52 +/- 1.80 diopters [D]) and 2 eyes were myopic (-1.12 +/- 0.53 D). Near, intermediate, and distance visual acuities were assessed at 1 and 6 months postoperatively. At last follow-up, patients were asked about their overall satisfaction, the occurrence of photic phenomena, difficulties driving at night, and spectacle independence. Six months after surgery and laser retreatment in 15 eyes, 90% of eyes achieved monocular uncorrected distance visual acuity of 20/30 or better (0.087 +/- 0.085 logMAR) and 100% of eyes could read J2 or better without correction, including 90% of eyes achieving J1 or better (0.133 +/- 0.095 logMAR). Evaluation of visual performance at 1 month versus 6 months (n = 44 eyes, no retreatment) revealed a considerable improvement of the uncorrected (0.175 +/- 0.122 vs 0.127 +/- 0.094 logMAR; P = .005) and distance-corrected (0.099 +/- 0.057 vs 0.068 +/- 0.031 logMAR; P = .001) near visual acuity whereas mean refractive errors and distance visual acuity remained unchanged. Overall, 96.4% of patients were very satisfied with the procedure and would choose the same lens again. The majority of patients (92.8%) were totally free from spectacles with only 7.2% occasionally wearing glasses for intermediate tasks. The multifocal Tecnis ZM900 IOL provides good distance and near vision after refractive lens exchange and a period of neuroadaptation. However, laser vision correction might be required to achieve emmetropia as well as spectacles to achieve good intermediate vision.

  5. Clinical Outcomes after Uncomplicated Cataract Surgery with Implantation of the Tecnis Toric Intraocular Lens

    PubMed Central

    Lubiński, Wojciech; Kaźmierczak, Beata; Gronkowska-Serafin, Jolanta; Podborączyńska-Jodko, Karolina

    2016-01-01

    Purpose. To evaluate the clinical outcomes after uncomplicated cataract surgery with implantation of an aspheric toric intraocular lens (IOL) during a 6-month follow-up. Methods. Prospective study including 27 consecutive eyes of 18 patients (mean age: 66.1 ± 11.4 years) with a visually significant cataract and corneal astigmatism ≥ 0.75 D and undergoing uncomplicated cataract surgery with implantation of the Tecnis ZCT toric IOL (Abbott Medical Optics). Visual, refractive, and keratometric outcomes as well as IOL rotation were evaluated during a 6-month follow-up. At the end of the follow-up, patient satisfaction and perception of optical/visual disturbances were also evaluated using a subjective questionnaire. Results. At 6 months after surgery, mean LogMAR uncorrected (UDVA) and corrected distance visual acuity (CDVA) were 0.19 ± 0.12 and 0.14 ± 0.10, respectively. Postoperative UDVA of 20/40 or better was achieved in 92.6% of eyes. Mean refractive cylinder decreased significantly from −3.73 ± 1.96 to −1.42 ± 0.88 D (p < 0.001), while keratometric cylinder did not change significantly (p = 0.44). Mean absolute IOL rotation was 1.1 ± 2.4°, with values of more than 5° in only 2 eyes (6.9%). Mean patient satisfaction score was 9.70 ± 0.46, using a scale from 0 (not at all satisfied) to 10 (very satisfied). No postoperative optical/visual disturbances were reported. Conclusion. Cataract surgery with implantation of the Tecnis toric IOL is an effective method of refractive correction in eyes with corneal astigmatism due to the good IOL positional stability, providing high levels of patient's satisfaction. PMID:27022478

  6. 7 CFR 1710.107 - Amount lent for acquisitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Amount lent for acquisitions. 1710.107 Section 1710... GUARANTEES Loan Purposes and Basic Policies § 1710.107 Amount lent for acquisitions. The maximum amount that will be lent for an acquisition is limited to the value of the property, as determined by RUS. If the...

  7. [Therapeutic qualities of a lente preparation of swine insulins manufactured by Pharmachem].

    PubMed

    Andreev, D; Bozadzhieva, E; Pampulov, L; Penchev, I; Uzunova, B

    1977-01-01

    The therapeutic effect of swine insulin preparation Lente, "Pharmachim" production was studied in 50 diabetics. Its hypoglycemizing activitis compared with that of standardized insulin Lente--"Novo", extract of bovine pancreas. The Bulgarian preparation was found to be very similar to the preparation Lente-Novo in its pharma-codynamic properties and could successfully be used in the diabetes melitus treatment. Insulin Lente Pharmachim is presumed to have lower antigenicity as an extract of swine pancreas, which is actually its great advantage for the therapeutic practice.

  8. 12 CFR 7.1003 - Money lent at banking offices or at other than banking offices.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 1 2013-01-01 2013-01-01 false Money lent at banking offices or at other than... TREASURY BANK ACTIVITIES AND OPERATIONS Bank Powers § 7.1003 Money lent at banking offices or at other than...(j) and 12 CFR 5.30, “money” is deemed to be “lent” only at the place, if any, where the borrower...

  9. 12 CFR 7.1003 - Money lent at banking offices or at other than banking offices.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 1 2014-01-01 2014-01-01 false Money lent at banking offices or at other than... TREASURY BANK ACTIVITIES AND OPERATIONS Bank Powers § 7.1003 Money lent at banking offices or at other than...(j) and 12 CFR 5.30, “money” is deemed to be “lent” only at the place, if any, where the borrower...

  10. 12 CFR 7.1003 - Money lent at banking offices or at other than banking offices.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 1 2012-01-01 2012-01-01 false Money lent at banking offices or at other than... TREASURY BANK ACTIVITIES AND OPERATIONS Bank Powers § 7.1003 Money lent at banking offices or at other than...(j) and 12 CFR 5.30, “money” is deemed to be “lent” only at the place, if any, where the borrower...

  11. 12 CFR 7.1003 - Money lent at banking offices or at other than banking offices.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Money lent at banking offices or at other than... TREASURY BANK ACTIVITIES AND OPERATIONS Bank Powers § 7.1003 Money lent at banking offices or at other than...(j) and 12 CFR 5.30, “money” is deemed to be “lent” only at the place, if any, where the borrower...

  12. Simplificando a luneta com lente de óculos

    NASA Astrophysics Data System (ADS)

    Canalle, J. B. G.; de Souza, A. C. F.

    2003-08-01

    A principal ferramenta de trabalho do astrônomo é o telescópio. O manuseio do mesmo é sempre motivo de enorme curiosidade por parte de alunos do ensino fundamental ou médio e até mesmo dos respectivos professores. Visando propiciar o acesso de alunos e professores ou interessados em geral a uma luneta de fácil construção, com materiais alternativos, de fácil localização no comércio, de baixo custo, resistente ao manuseio de alunos, simplificamos a montagem de uma luneta construída com lente de óculos, de 1 ou 2 graus positivos, e monóculo de fotografia, publicado por este autor no CCEF, vol.11(3), 212, 1994. Esta luneta, a qual permite ver as crateras lunares, apresentava como maior dificuldade de construção o tripé e o local de formação da imagem. Substituímos o tripé de madeira por uma simples garrafa PET de 2 litros cheia d'água. No lugar da ocular usamos a lente do monóculo de fotografia (ou visor de fotografia) encaixado dentro de uma bucha de redução curta, de 40 x 32 mm, e esta não mais dentro de uma luva (conexão hidráulica) de 40 mm de diâmetro, mas sim encostada no próprio tubo de PVC móvel (o qual permite o ajuste do foco) de 40 mm de diâmetro e presa a este por outro tubo de 40 mm de diâmetro e 10 cm de comprimento, serrado ao longo do seu comprimento. Com isto podemos ajustar a posição deste tubo de 10 cm também para que uma das suas extremidades coincida com o local de formação da imagem. Desta forma o observador saberá o local exato da formação da imagem, o que não era evidente na montagem anterior e causava uma dificuldade inicial até se descobrir a posição exata em que se deveria colocar o olho. Deste maneira, a montagem inicial que já era simples ficou ainda mais simples, mais barata e mais confortável para o uso. Um exemplar da mesma será exposto durante a XXIX Reunião Anual da Sociedade Astronômica Brasileira para inspeção e uso dos participantes.

  13. Use of glargine and lente insulins in cats with diabetes mellitus.

    PubMed

    Weaver, Kelli E; Rozanski, Elizabeth A; Mahony, Orla M; Chan, Daniel L; Freeman, Lisa M

    2006-01-01

    The goals of this study were to compare the efficacy of once-daily administered Glargine insulin to twice-daily administered Lente insulin in cats with diabetes mellitus and to describe the use of a high-protein, low-carbohydrate diet designed for the management of diabetes mellitus in cats. All cats with naturally occurring diabetes mellitus were eligible for inclusion. Baseline testing included a physical examination, serum biochemistry, urinalysis and urine culture, serum thyroxine concentration, and serum fructosamine concentration. All cats were fed the high-protein, low-carbohydrate diet exclusively. Cats were randomized to receive either 0.5 U/kg Lente insulin q12h or 0.5 U/kg Glargine insulin q24h. Re-evaluations were performed on all cats at weeks 1, 2, 4, 8, and 12, and included an assessment of clinical signs, physical examination, 16-hour blood glucose curve, and serum fructosamine concentrations. Thirteen cats completed the study (Lente, n = 7, Glargine, n = 6). There was significant improvement in serum fructosamine and glucose concentrations in all cats but there was no significant difference between the 2 insulin groups. Four of the 13 cats were in complete remission by the end of the study period (Lente, n = 3; Glargine, n = 1). The results of the study support the use of once-daily insulin Glargine or twice-daily Lente insulin in combination with a high-protein, low-carbohydrate diet for treatment of feline diabetes mellitus.

  14. Late radiation effects to the rectum and anus after treatment for prostate cancer; validity of the LENT/SOMA score.

    PubMed

    Lund, Jo-Å; Kaasa, Stein; Wibe, Arne; Widmark, Anders; Fransson, Per

    2013-05-01

    The Late Effects Normal Tissue/Subjective Objective Management Analytic (LENT/SOMA) system for grading of side effects after radiotherapy was proposed several years ago. Only a few studies have previously been performed on the validity of the LENT/SOMA. The aim of the present study was to validate the LENT/SOMA scoring system for recto-anal side effects after treatment for prostate cancer in a randomized trial. A total of 875 patients with locally advanced prostate cancer were randomized to either hormonal treatment alone or hormonal treatment plus radiotherapy in the Scandinavian Prostate Cancer Group 7 (SPCG-7) study. At least three years after treatment was started, the 178 patients that were randomized at St. Olavs Hospital were approached. One hundred and three patients of these accepted inclusion. The side effects according to LENT/SOMA were graded by oncologist and nurse. In addition, side effects were graded according to the European Organisation for Research and Treatment of Cancer and the Radiation Therapy Oncology Group (EORTC/RTOG) toxicity scale and patient-reported health-related quality of life (HRQOL) questionnaires. Content/face validity, sensitivity and inter-rater reliability of the LENT/SOMA tables for rectum were analyzed. Content/face analysis of LENT/SOMA revealed serious problems. Significant correlations (Spearman's rho > 0.4) were found between three of 15 LENT/SOMA items and similar HRQOL items. LENT/SOMA score made it possible to detect significant differences between the two groups of patients (p < 0.001), EORTC/RTOG toxicity score did not (p = 0.138). Inter-rater reliability was acceptable. LENT/SOMA scoring system for recto-anal side effects after radiotherapy for prostate cancer displays serious difficulties in the present study. Replacement of LENT/SOMA tables for rectum by a combination of patient-reported HRQOL questionnaires, clinical examination and objective physiological measurements might be called for.

  15. 48 CFR 252.223-7008 - Prohibition of Hexava-lent Chromium.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Chromium. 252.223-7008 Section 252.223-7008 Federal Acquisition Regulations System DEFENSE ACQUISITION... of Provisions And Clauses 252.223-7008 Prohibition of Hexava-lent Chromium. As prescribed in 223.7306, use the following clause: Prohibition of Hexavalent Chromium (JUN 2013) (a) Definitions. As used...

  16. Lent-On-Plus Lentiviral vectors for conditional expression in human stem cells.

    PubMed

    Benabdellah, Karim; Muñoz, Pilar; Cobo, Marién; Gutierrez-Guerrero, Alejandra; Sánchez-Hernández, Sabina; Garcia-Perez, Angélica; Anderson, Per; Carrillo-Gálvez, Ana Belén; Toscano, Miguel G; Martin, Francisco

    2016-11-17

    Conditional transgene expression in human stem cells has been difficult to achieve due to the low efficiency of existing delivery methods, the strong silencing of the transgenes and the toxicity of the regulators. Most of the existing technologies are based on stem cells clones expressing appropriate levels of tTA or rtTA transactivators (based on the TetR-VP16 chimeras). In the present study, we aim the generation of Tet-On all-in-one lentiviral vectors (LVs) that tightly regulate transgene expression in human stem cells using the original TetR repressor. By using appropriate promoter combinations and shielding the LVs with the Is2 insulator, we have constructed the Lent-On-Plus Tet-On system that achieved efficient transgene regulation in human multipotent and pluripotent stem cells. The generation of inducible stem cell lines with the Lent-ON-Plus LVs did not require selection or cloning, and transgene regulation was maintained after long-term cultured and upon differentiation toward different lineages. To our knowledge, Lent-On-Plus is the first all-in-one vector system that tightly regulates transgene expression in bulk populations of human pluripotent stem cells and its progeny.

  17. Lent-On-Plus Lentiviral vectors for conditional expression in human stem cells

    PubMed Central

    Benabdellah, Karim; Muñoz, Pilar; Cobo, Marién; Gutierrez-Guerrero, Alejandra; Sánchez-Hernández, Sabina; Garcia-Perez, Angélica; Anderson, Per; Carrillo-Gálvez, Ana Belén; Toscano, Miguel G.; Martin, Francisco

    2016-01-01

    Conditional transgene expression in human stem cells has been difficult to achieve due to the low efficiency of existing delivery methods, the strong silencing of the transgenes and the toxicity of the regulators. Most of the existing technologies are based on stem cells clones expressing appropriate levels of tTA or rtTA transactivators (based on the TetR-VP16 chimeras). In the present study, we aim the generation of Tet-On all-in-one lentiviral vectors (LVs) that tightly regulate transgene expression in human stem cells using the original TetR repressor. By using appropriate promoter combinations and shielding the LVs with the Is2 insulator, we have constructed the Lent-On-Plus Tet-On system that achieved efficient transgene regulation in human multipotent and pluripotent stem cells. The generation of inducible stem cell lines with the Lent-ON-Plus LVs did not require selection or cloning, and transgene regulation was maintained after long-term cultured and upon differentiation toward different lineages. To our knowledge, Lent-On-Plus is the first all-in-one vector system that tightly regulates transgene expression in bulk populations of human pluripotent stem cells and its progeny. PMID:27853296

  18. Predicting survival in malignant pleural effusion: development and validation of the LENT prognostic score.

    PubMed

    Clive, Amelia O; Kahan, Brennan C; Hooper, Clare E; Bhatnagar, Rahul; Morley, Anna J; Zahan-Evans, Natalie; Bintcliffe, Oliver J; Boshuizen, Rogier C; Fysh, Edward T H; Tobin, Claire L; Medford, Andrew R L; Harvey, John E; van den Heuvel, Michel M; Lee, Y C Gary; Maskell, Nick A

    2014-12-01

    Malignant pleural effusion (MPE) causes debilitating breathlessness and predicting survival is challenging. This study aimed to obtain contemporary data on survival by underlying tumour type in patients with MPE, identify prognostic indicators of overall survival and develop and validate a prognostic scoring system. Three large international cohorts of patients with MPE were used to calculate survival by cell type (univariable Cox model). The prognostic value of 14 predefined variables was evaluated in the most complete data set (multivariable Cox model). A clinical prognostic scoring system was then developed and validated. Based on the results of the international data and the multivariable survival analysis, the LENT prognostic score (pleural fluid lactate dehydrogenase, Eastern Cooperative Oncology Group (ECOG) performance score (PS), neutrophil-to-lymphocyte ratio and tumour type) was developed and subsequently validated using an independent data set. Risk stratifying patients into low-risk, moderate-risk and high-risk groups gave median (IQR) survivals of 319 days (228-549; n=43), 130 days (47-467; n=129) and 44 days (22-77; n=31), respectively. Only 65% (20/31) of patients with a high-risk LENT score survived 1 month from diagnosis and just 3% (1/31) survived 6 months. Analysis of the area under the receiver operating curve revealed the LENT score to be superior at predicting survival compared with ECOG PS at 1 month (0.77 vs 0.66, p<0.01), 3 months (0.84 vs 0.75, p<0.01) and 6 months (0.85 vs 0.76, p<0.01). The LENT scoring system is the first validated prognostic score in MPE, which predicts survival with significantly better accuracy than ECOG PS alone. This may aid clinical decision making in this diverse patient population. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  19. Assessment of morbidity in carcinoma of the cervix: a comparison of the LENT SOMA scales and the Franco-Italian glossary.

    PubMed

    Davidson, Susan E; Burns, Meriel P; Routledge, Jacqueline A; Swindell, Ric; Bentzen, Søren M; West, Catharine M L

    2003-11-01

    To assess the correlation between the LENT (late effects on normal tissue) SOMA (subjective objective management analytic) system and the Franco-Italian glossary scores of late morbidity in cervical cancer patients treated with radiation, and to compare the ability of the scoring systems to detect differences between radiation treatment groups. The study was retrospective. Patients, invited to take part in the study, had radiotherapy for cervical cancer and had a minimum of 3 years follow-up with no evidence of recurrence. One hundred patients agreed to take part. LENT subjective data were obtained using a patient questionnaire approach in order to complete the scales as published. The LENT objective, management and Franco-Italian glossary scores were obtained by a physician. Correlations between scores and differences between treatment groups were examined using non-parametric tests. The average LENT SOMA scores had a greater resolution than the maximum scores, and using the maximum score alone underestimated treatment morbidity. The Franco-Italian glossary scores correlated strongly with the LENT objective scores (rho=0.61, P<0.0005), and less strongly with the LENT subjective scores (rho=0.45, P<0.0005). Significant differences in morbidity between the radiation treatment groups were measured using both the LENT SOMA system and the Franco-Italian glossary. The maximum and average LENT scores should be reported for each subsite. The LENT objective scores correlated well with the scores obtained using the established Franco-Italian glossary, but the LENT system provided additional information on subjective treatment effects. Both systems were able to measure significant differences in morbidity between radiation treatment groups. In conclusion, the LENT SOMA system is a valid and comprehensive approach for scoring the late normal tissue effects of radiotherapy.

  20. Theoretical and Methodological Issues with Testing the SCCT and RIASEC Models: Comment on Lent, Sheu, and Brown (2010) and Lubinski (2010)

    ERIC Educational Resources Information Center

    Armstrong, Patrick Ian; Vogel, David L.

    2010-01-01

    The current article replies to comments made by Lent, Sheu, and Brown (2010) and Lubinski (2010) regarding the study "Interpreting the Interest-Efficacy Association From a RIASEC Perspective" (Armstrong & Vogel, 2009). The comments made by Lent et al. and Lubinski highlight a number of important theoretical and methodological issues, including the…

  1. Theoretical and Methodological Issues with Testing the SCCT and RIASEC Models: Comment on Lent, Sheu, and Brown (2010) and Lubinski (2010)

    ERIC Educational Resources Information Center

    Armstrong, Patrick Ian; Vogel, David L.

    2010-01-01

    The current article replies to comments made by Lent, Sheu, and Brown (2010) and Lubinski (2010) regarding the study "Interpreting the Interest-Efficacy Association From a RIASEC Perspective" (Armstrong & Vogel, 2009). The comments made by Lent et al. and Lubinski highlight a number of important theoretical and methodological issues, including the…

  2. Estatística de lentes gravitacionais e o gás de chaplygin generalizado

    NASA Astrophysics Data System (ADS)

    Oliveira, A. L. S.

    2003-08-01

    A estatística de lentes gravitacionais constitui uma poderosa ferramenta utilizada na obtenção de vínculos sobre parâmetros cosmológicos, principalmente sobre modelos com uma constante cosmológica. Embora de forma às vezes controversa, antes de 1998, a análise tradicional mostrava que modelos com o parâmetro de densidade da matéria da ordem da unidade são preferidos. Esse resultado começou a ser questionado, alguns anos atrás, com as indicações, advindas da análise de supernovas com alto valor de desvio para o vermelho, de que nosso Universo está acelerando. Atualmente há enorme interesse em saber qual é a natureza da componente responsável pela aceleração cósmica. Energia escura é a denominação usual dessa componente e sua característica principal é possuir pressão negativa. Nos modelos cosmológicos tradicionais, além da energia escura, considera-se também uma outra componente de origem desconhecida. Ela é denominada matéria escura e possui pressão nula. Mais recentemente modelos unificadores em que energia escura e matéria escura são manifestações distintas de um mesmo fluido (altas densidades matéria escura, baixas densidades energia escura) foram sugeridos. Um desses modelos é conhecido como Gás de Chaplygin Generalizado que é o modelo que investigaremos. Em nosso trabalho apresentamos vínculos sobre parâmetros desse modelo usando a estatística de lentes gravitacionais. Usamos observações de quasares na faixa do visível e consideramos extinção em nosso estudo. Análises semelhantes anteriores com esse tipo de objetos e que não consideram extinção são inconsistentes. Comparação dos vínculos obtidos através de lentes gravitacionais com outros advindos de outros testes será também apresentada.

  3. Increasing the rate of late toxicity by changing the score? A comparison of RTOG/EORTC and LENT/SOMA scores.

    PubMed

    Hoeller, Ulrike; Tribius, Silke; Kuhlmey, Antje; Grader, Kai; Fehlauer, Fabian; Alberti, Winfried

    2003-03-15

    The Radiation Therapy Oncology Group (RTOG) and Late Effects Normal Tissue Task Force subjective, objective, management, and analytic (LENT/SOMA) scores were compared in a group of breast cancer patients. The impact of the classification system on grading late effects was evaluated. Telangiectasia, skin pigmentation, and fibrosis were scored according to both LENT/SOMA and RTOG criteria. The results were compared with respect to up- or downgrading and correlated (Spearman's rho). Other side effects were recorded using LENT/SOMA criteria. Interobserver variability was calculated with Cohen's kappa. Two hundred fifty-nine subsequent relapse-free patients who underwent breast-conserving therapy between 1981 and 1995 were examined. The median dose of radiotherapy to the breast was 55 Gy. Adjuvant chemotherapy was given to 31 patients and tamoxifen to 52 patients. The median follow-up was 8 years. RTOG skin and s.c. tissue scales and LENT/SOMA breast and pigmentation scales were used. Two doctors examined 45 patients jointly. Of all patients, 20% had telangiectasia, 22% pigmentation, 43% fibrosis, 4% breast edema, 77% retraction/atrophy, and 54% pain. In comparison, when LENT/SOMA criteria were used, telangiectasia and pigmentation were upgraded in 34% and 36%, respectively, and telangiectasia was downgraded in 45%. Fibrosis correlated well (Spearman's rho 0.78, p = 0.01). An additional 356 side effects, mainly retraction/atrophy were observed in 226 patients using LENT/SOMA criteria. Interobserver variability was similar for both classification systems and ranged from Cohen's kappa 0.3 (retraction) to 0.91 (telangiectasia). LENT/SOMA criteria seem to be the better tool in grading and recording late radiation toxicity compared with the RTOG scale. There was some upgrading with the RTOG score when skin toxicity is evaluated. In contrast, fibrosis scores correlated very well. Adjustments of the LENT/SOMA scoring system should be considered to standardize reporting of late

  4. Assessment of the insecticidal potential of Eucalyptus urograndis essential oil against Rhodnius neglectus Lent (Hemiptera: Reduviidae).

    PubMed

    Gomes, S P; Favero, S

    2013-08-01

    The resistance of triatomines to pyrethroids has been reported in several Latin American countries, including Brazil, indicating the need for the development of new approaches for the control of vectors of the Chagas disease. In here, we evaluated the insecticidal potential of the essential oil of Eucalyptus urograndis (Myrtaceae) against unsexed third and fourth instars of Rhodnius neglectus Lent (Hemiptera: Reduviidae) in topical application, fumigation, surface contact, and repellency . The insecticidal activity of the essential oil tested was detected by topical application (LD50 = 0.1731 μL/insect and LD99 = 0.2948 μL/insect for 24 h), fumigation (LC50 = 0.021 mL/mL air and LC99 = 0.1525 mL/mL air for 24 h) and surface contact (LC50 = 0.7073 μL/cm(2) and LC99 = 4.59 μL/cm(2) for 24 h). Mortality observed after 48-72-h exposure was very high and did not allow for any adjustment of the mortality curve. In the repellency assay, an effect was observed on 80% of tested nymphs. However, no repellency was observed after 24 h of exposure. Eucalyptus urograndis essential oil has a high insecticidal and repellent potential for R. neglectus nymphs, whether serving as a molecular model for new substances or as an alternative for the control of these insects.

  5. Comparing the RTOG/EORTC and LENT-SOMA scoring systems for the evaluation of late skin toxicity after (125)I seed brachytherapy for parotid gland cancer.

    PubMed

    Mao, Ming-Hui; Feng, Zhien; Li, Hua; Qin, Li-Zheng; Li, Jian-Hua; Huang, Xin; Xing, Ru-Dong; Zhang, Jie; Zhang, Jian-Guo; Han, Zheng-Xue

    The Radiation Therapy Oncology Group (RTOG) and Late Effects Normal Tissue Task Force-Subjective, Objective, Management and Analytic (LENT-SOMA) scoring systems were compared for grading late skin effects after iodine-125 seed brachytherapy in parotid gland cancer patients. A total of 109 patients diagnosed with parotid gland carcinoma were treated postoperatively with iodine-125 seed brachytherapy at a dose of 100-120 Gy. After 6-24 months of followup, telangiectasia, skin pigmentation, atrophy, fibrosis, and ulceration were scored according to both RTOG and LENT-SOMA scale criteria. The strength of correlation between the scores and the interobserver variability were calculated. Of 109 patients, 22.9% had telangiectasia; 78.9%, pigmentation; 28.4%, fibrosis; 4.6%, edema; 0.9%, ulceration; 37.6%, retraction and/or atrophy; 22.9%, sensation change; and 11%, scaliness and/or roughness. Compared with RTOG, LENT-SOMA criteria resulted in the upgrading of pigmentation in 17% of cases, the downgrading of all instances of telangiectasia and the downgrading of one instance of Grade 4 ulceration to Grade 3. Between the two scales, fibrosis and atrophy correlated well (Spearman ρ, 0.992, 0.986). An additional 229 side effects were observed using LENT-SOMA criteria. The LENT-SOMA scale was more accurate than the RTOG scale for the evaluation of late skin and subcutaneous toxicity. The downgrading of telangiectasia and upgrading of pigmentation with the LENT-SOMA scale reflected the patients' conditions better than the scores obtained with the RTOG scale. The assessment of fibrosis and atrophy correlated well between the two scales. The use of the sum of the individual scores of the LENT-SOMA is therefore advocated. The addition of decreased sweating and the removal of the alopecia (scalp) metric should be considered to standardize the reporting of late radiation morbidity. Copyright © 2017 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.

  6. [Eduard Lent (1831-1911): founder and supporter of public health care, social institutions, and physician self-management].

    PubMed

    Lent, V

    2014-06-01

    Modern urology owes much to our predecessors. Researchers in the 20th century were able to develop their specialist techniques and their professional independence on the basis of the fundamental studies and measures carried out by their predecessors in the 19th century. As a medical practitioner, Eduard Lent provided pioneering solutions to the three major sociomedical problems of his time, namely wide-spread epidemics like cholera, social inequalities, and lack of organization of the medical profession. His answer are to be found in the organization of public healthcare, establishment of suitable social institutions, and the promotion of self-government of the medical profession. These achievements have left their imprint on many fields, including urology.

  7. Apport de l’IRM dans la prise en charge des compressions médullaires lentes non traumatiques

    PubMed Central

    Badji, Nfally; Deme, Hamidou; Akpo, Geraud; Ndong, Boucar; Toure, Mouhamadou Hamine; Diop, Sokhna Ba; Niang, El Hadji

    2016-01-01

    Les compressions médullaires lentes sont dues au développement dans le canal médullaire d’une lésion expansive. C’est une pathologie très fréquente dont le diagnostic est essentiellement clinique. L’imagerie par résonnance magnétique occupe une place incontournable dans le diagnostic de localisation et la recherche étiologique. En Europe l’étiologie tumorale est prépondérante. Le but de cette étude était de décrire les aspects IRM des compressions médullaires lentes et de déterminer le profil étiologique. Il s’agit d’une étude rétrospective portant sur 97 observations colligées au service de radiologie du CHUN de Fann sur une période de 30 mois (du 08/03/10 au 29/09/12). On été inclus dans l’étude, tous les patients adressés pour un tableau de compression médullaire lente survenu dans un contexte non traumatique. L’âge moyen des patients était de 42,6 ans avec des extrêmes compris entre 04 mois et 85 ans. Nous avons étudié la topographie des lésions (étage rachidien, compartiments canalaires) leur rehaussement et les critères d’orientation étiologique. Le protocole d’examen permettait la réalisation de séquence pondérées T1 sans avec injection de gado, T2, STIR et T2 DRIVE centrées sur les niveaux lésionnels ou les zones suspectes. L’IRM a permis de préciser le siège exact et l’étendue des lésions. L’atteinte du rachis dorsal représentait 42% des cas, suivi du rachis cervical avec 32% des cas. Les atteintes lombo-sacrées et pluri-étagées représentaient respectivement 18% et 08% des cas. Les lésions extradurales représentaient 87% des cas, suivi des lésions intradurales extramédullaires avec 08% des cas et des lésions intramédullaires dans 05% des cas. La particularité du profil étiologique de notre étude est la prédominance des épidurites infectieuses et la fréquence relative des épidurites métastatiques comparée aux séries occidentales. L’IRM vertébro-médullaire occupe

  8. [Natural helminth infection in Sicalis flaveola (Linnaeus, 1766), by Acuaria mayori Lent, Freitas and Proença, 1945 (Nematoda: Acuarioidea) in Brazil].

    PubMed

    Rodrigues, Maria L de A; Muniz-Pereira, Luís C; Pinto, Roberto M; Lins, Fernanda P; Riehl Vaz, Mônica G; de Abreu, Ana Paula M; de Souza, Paulo César A

    2005-01-01

    This is the first report of a natural infection in the saffron finch Sicalis flaveola (Linnaeus, 1766) captured in Brazil, with the establishment of a new host record for the acuarioid nematode Acuaria mayori Lent, Freitas and Proença, 1945, previously referred in Cyanocorax chrysops (Vieillot, 1818) from Paraguay and Sporophila caerulescens caerulescens (Vieillot, 1823) and C. cyanomelas (Wied, 1821) from Brazil and Myarchus nuttingi (Ridgway, 1883) from Costa Rica.

  9. Comparison of patient-reported late treatment toxicity (LENT-SOMA) with quality of life (EORTC QLQ-C30 and QLQ-H&N35) assessment after head and neck radiotherapy.

    PubMed

    Ho, Kean Fatt; Farnell, Damien J J; Routledge, Jacqueline A; Burns, Meriel P; Sykes, Andrew J; Slevin, Nick J; Davidson, Susan E

    2010-11-01

    The patient's role in toxicity reporting is increasingly acknowledged but requires the adaptation and validation of toxicity reporting instruments for patient use as most toxicity scales are designed for physician use. Recording of radiotherapy related late toxicity is important and needs to be improved. A patient-scored symptom questionnaire of late treatment effects using LENT-SOMA was compared with a recognised quality of life tool (EORTC QLQ-C30/H&N35). LENT-SOMA and EORTC QLQ-C30 patient questionnaires were prospectively completed by 220 head and neck cancer patients over 3 years and 72 completed EORTC QLQ-H&N35 questionnaires at 2 years post-radiotherapy. Endpoints common to both questionnaires (pain, swallowing, dental pain, dry mouth, opening mouth, analgesics) were matched. Spearman rank correlation coefficients with ρ>0.6 (P<0.001) were obtained for all "matched" scales except for analgesics scale, ρ=0.267 (P<0.05). There was good agreement between LENT-SOMA and EORTC QLQ-H&N35 except for analgesic endpoints. Global quality of life scores correlated negatively with average LENT-SOMA scores (P<0.001). Significant differences in average LENT-SOMA scores between treatment modalities were found. The LENT-SOMA questionnaire has demonstrated a high Cronbach's α value (0.786) indicating good reliability. LENT-SOMA patient questionnaire results agreed well with those from the EORTC QLQ-H&N35 questionnaire for toxicity items where they could be compared explicitly, particularly for subjective endpoints. Patient-reported late toxicity had a negative impact on quality of life. The LENT-SOMA patient questionnaire is both reliable and sensitive to differences between patients treated with different modalities. A patient-based questionnaire is an important contributor to capturing late radiotherapy effects. Copyright © 2010. Published by Elsevier Ireland Ltd.

  10. Theoretical and methodological issues with testing the SCCT and RIASEC models: Comment on Lent, Sheu, and Brown (2010) and Lubinski (2010).

    PubMed

    Armstrong, Patrick Ian; Vogel, David L

    2010-04-01

    The current article replies to comments made by Lent, Sheu, and Brown (2010) and Lubinski (2010) regarding the study "Interpreting the Interest-Efficacy Association From a RIASEC Perspective" (Armstrong & Vogel, 2009). The comments made by Lent et al. and Lubinski highlight a number of important theoretical and methodological issues, including the process of defining and differentiating between constructs, the assumptions underlying Holland's (1959, 1997) RIASEC (Realistic, Investigative, Artistic, Social, Enterprising, and Conventional types) model and interrelations among constructs specified in social cognitive career theory (SCCT), the importance of incremental validity for evaluating constructs, and methodological considerations when quantifying interest-efficacy correlations and for comparing models using multivariate statistical methods. On the basis of these comments and previous research on the SCCT and Holland models, we highlight the importance of considering multiple theoretical perspectives in vocational research and practice. Alternative structural models are outlined for examining the role of interests, self-efficacy, learning experiences, outcome expectations, personality, and cognitive abilities in the career choice and development process.

  11. Detecção inesperada de efeitos de lentes fracas em grupos de galáxias pouco luminosos em raios-X

    NASA Astrophysics Data System (ADS)

    Carrasco, R.; Mendes de Oliveira, C.; Sodrã©, L., Jr.; Lima Neto, G. B.; Cypriano, E. S.; Lengruber, L. L.; Cuevas, H.; Ramirez, A.

    2003-08-01

    Obtivemos, como parte do programa de verificação científica do GMOS Sul, imagens profundas de três grupos de galáxias: G97 e G102 (z~0,4) e G124 (z = 0,17). Esses alvos foram selecionados a partir do catálogo de fontes extensas de Vikhlinin (1998), por terem luminosidades em raios X menores que 3´1043 ergs s-1, valor cerca de uma ou duas ordens de grandeza inferior ao de aglomerados de galáxias. O objetivo primário dessas observações é o estudo da evolução de galáxias em grupos. Grupos são ambientes menos densos que aglomerados, contêm a grande maioria das galáxias do Universo mas que, até o momento, foram estudados detalhadamente apenas no Universo local (z~0). Com esses dados efetuamos uma análise estatística da distorção na forma das galáxias de fundo (lentes gravitacionais fracas) como forma de inferir o conteúdo e a distribuição de massa nesses grupos apesar de que, em princípio, esse efeito não deveria ser detectado uma vez que os critérios de seleção adotados previlegiam sistemas de baixa massa. De fato, para G124 obtivemos apenas um limite superior para sua massa que é compatível com sua luminosidade em raios X. De modo contrário e surpreendente, os objetos G102 e G097, aparentam ter massas que resultariam em dispersões de velocidade maiores que 1000 km s-1, muito maiores do que se espera para grupos de galáxias. Com efeito, para G097 obtivemos, a partir de dados do satélite XMM, uma estimativa para a temperatura do gás intragrupo de kT = 2,6 keV, que é tipica de sistemas com dispersões de velocidade de ~ 600 km s-1, bem característica de grupos. Essas contradições aparentes entre lentes fracas e raios X podem ser explicadas de dois modos: i) a massa obtida por lentes estaria sobreestimada devido à superposição de estruturas massivas ao longo da linha de visada ou ii) a temperatura do gás do meio intra-grupo reflete o potencial gravitacional de estruturas menores que estariam se fundindo para formar uma

  12. Isolated limb perfusion and external beam radiotherapy for soft tissue sarcomas of the extremity: long-term effects on normal tissue according to the LENT-SOMA scoring system.

    PubMed

    Hoven-Gondrie, Miriam L; Thijssens, Katja M J; Geertzen, Jan H B; Pras, Elisabeth; van Ginkel, Robert J; Hoekstra, Harald J

    2008-05-01

    With the combined treatment procedure of isolated limb perfusion (ILP), delayed surgical resection and external beam radiotherapy (EBRT) for locally advanced soft tissue sarcomas (STS) of the extremities, limb salvage rates of more than 80% can be achieved. However, long-term damage to the healthy surrounding tissue cannot be prevented. We studied the late effects on the normal tissue using the LENT-SOMA scoring system. A total of 32 patients-median age 47 (range 14-71) years-were treated for a locally advanced STS with ILP, surgical resection and often adjuvant 60-70 Gy EBRT. After a median follow-up of 88 (range 17-159) months, the patients were scored, using the LENT-SOMA scales, for the following late tissue damage: muscle/soft tissue, peripheral nerves, skin/subcutaneous tissue and vessels. According to the individual SOM parameters of the LENT-SOMA scales, 20 patients (63%) scored grade-3 toxicity on one or more separate items, reflecting severe symptoms with a negative impact on daily activities. Of these patients, 3 (9%) even scored grade-4 toxicity on some of the parameters, denoting irreversible functional damage necessitating major therapeutic intervention. In evaluating long-term morbidity after a combined treatment procedure for STS of the extremity, using modified LENT-SOMA scores, two-thirds of patients were found to have experienced serious late toxic effects.

  13. Description of the male genitalia of Belminus rugulosus Stål and Belminus corredori Galvão & Angulo, and comments on the holotype of Parabelminus yurupucu Lent & Wygodzinsky (Hemiptera: Heteroptera: Reduviidae: Triatominae: Bolboderini).

    PubMed

    Gil-Santana, Hélcio R; Galvão, Cleber

    2013-12-13

    The male genitalia of Belminus rugulosus Stål and Belminus corredori Galvão & Angulo are described and illustrated for the first time. Comments on the holotype of Parabelminus yurupucu Lent & Wygodzinsky are presented (Hemiptera: Heteroptera: Reduviidae: Triatominae: Bolboderini). A discussion on previous data in the literature on male genitalia of species of Belminus Stål is provided.

  14. Glare disability and spherical aberration with five foldable intraocular lenses: a prospective randomized study.

    PubMed

    Casprini, Fabrizio; Balestrazzi, Angelo; Tosi, Gian Marco; Miracco, Flavia; Martone, Gianluca; Cevenini, Gabriele; Caporossi, Aldo

    2005-02-01

    To compare differences in subjective glare and spherical aberration between five foldable intraocular lenses (IOLs) made of different materials and to different designs. This prospective study comprised 175 cataract patients who underwent phacoemulsification and were randomized to receive one of five types of foldable IOL (AcrySof MA30BA, Alcon; Sensar AR40, AMO; AcrySof SA30AL, Alcon; Sensar AR40e, AMO, and Tecnis Z9000, Pharmacia & Upjohn). All patients received a questionnaire investigating the incidence of subjective photic phenomena. Two months postoperatively, we collected data regarding subjective glare and evaluated pupil size, visual acuity and wavefront aberration of the cornea and eye. With regard to difficulty in performing ordinary activities under different light conditions and light and dark adaptation, the difference between the groups was not significant (p > 0.05, chi-squared test). With respect to difficulty in driving at night, the MA30BA group had a significant higher incidence of photic phenomena than the SA30AL, AR40e and Z9000 groups (p < 0.05, chi-squared test). Wavefront measurements revealed a significant difference between the Z9000, AR40e and SA30AL groups, which showed the lowest values, and the MA30BA group, which showed the highest value (p < 0.05, anova with Tamhane posthoc test). New generation IOLs such as the Pharmacia Z9000, AMO AR40e and AcrySof SA30AL have a lower incidence of glare and spherical aberrations; however, their impact on future IOL design should be conditioned by further data, especially regarding posterior capsule opacification.

  15. Redescriptions of the nematodes Litomosoides patersoni (Mazza, 1928) (Onchocercidae) and Stilestrongylus stilesi Freitas, Lent, and Almeida, 1937 (Heligmonellidae) parasites of Holochilus chacarius (Rodentia, Cricetidae) from Salta, Argentina.

    PubMed

    Notarnicola, Juliana; Digiani, María Celina; López, Pablo Martín

    2010-10-01

    Two nematode species are redescribed from the type host species Holochilus chacarius Thomas (Rodentia, Cricetidae, Sigmodontinae) and from the type locality of 1 of them, i.e., Ingenio San Martín de Tabacal, Salta Province, Argentina. Rodents were deposited at the Colección Mamíferos Lillo, Tucumán, Argentina. Litomosoides patersoni (Mazza, 1928) (Onchocercidae) possesses a buccal capsule with irregular external walls, a buccal cavity smooth, becoming thinner near the oral opening, a complete set of head papillae, 3-6 pairs of cloacal papillae, and the " sigmodontis " type of spicules. Filarioids were found in 3 of 17 examined hosts. Stilestrongylus stilesi Freitas, Lent, and Almeida, 1937 (Heligmonellidae), whose description was based on male specimens, was found in all 17 of the examined hosts. Here, we describe the female and the synlophe of both sexes. Females are characterized by a short uterus with less than 25 eggs, short ovejector, short and conical tail, and the posterior extremity strongly invaginated in a cuticular expansion usually harboring 1 to several eggs. The synlophe is characterized by 29-31 sub-equal cuticular ridges at the mid-body, with single (in males) or double (in females) axis of orientation of the ridges. The present work validates and enlarges the original descriptions of both species and assigns the specimens from L. patersoni, recovered from the type locality and the type host species, as neotypes.

  16. Prospective randomized study of clinical performance of 3 aspheric and 2 spherical intraocular lenses in 250 eyes.

    PubMed

    Caporossi, Aldo; Martone, Gianluca; Casprini, Fabrizio; Rapisarda, Lorenzo

    2007-09-01

    To compare the quality of vision with aspheric and spherical intraocular lenses (IOLs) in pseudophakic patients. This prospective, comparative, randomized study included 250 eyes of 125 patients with bilateral cataracts. Patients were randomly assigned to receive either IOLs with a spherical biconvex optic (Acrysof SN6OAT [Alcon] or Sensar AR40e [Advanced Medical Optics, AMO]) or IOLs with an aspheric optic (Acrysof IQ SN6OWF [Alcon], Tecnis Z9000 [AMO], or Sofport L161AO [Bausch & Lomb]). Ophthalmologic examination including best spectacle-corrected visual acuity, pupil size, ocular dominance investigation, contrast sensitivity under mesopic and photopic conditions, and wavefront analysis was performed 2 months postoperatively. Aspheric IOLs showed better contrast sensitivity compared to spherical IOLs at spatial frequencies of 6, 12, and 18 cycles per degree (cpd) under photopic conditions and at all spatial frequencies under mesopic conditions. There was no significant difference among the three aspheric IOLs at all spatial frequencies under either photopic or mesopic conditions. Mean total spherical aberration was statistically lower in dominant eyes with aspheric IOLs (0.05 +/- 0.06, 0.11 +/- 0.1, and 0.19 +/- 0.08 pm for the Tecnis Z9000, Acrysof IQ SN6OWF, and Sofport L161AO, respectively) compared with eyes with spherical IOLs (0.62 +/- 0.24 and 0.46 +/- 0.19 microm for the Acrysof SN6OAT and Sensar AR40e, respectively) for a 5-mm pupil diameter. The aspheric IOLs had less wavefront aberrations and performed better under both photopic and mesopic contrast sensitivity compared to the spherical IOLs. These findings confirm it is possible to improve the optical performance of IOLs by modifying the surfaces.

  17. Mazzanema n. gen. and Mazzanema fortuita n. comb. for Longistriata fortuita Freitas, Lent, and Almeida, 1937 (Nematoda: Heligmonellidae), a parasite of the marsh rat Holochilus chacarius (Rodentia: Cricetidae) from northern Argentina.

    PubMed

    Digiani, María Celina; Notarnicola, Juliana; Paulos, María Soledad

    2013-10-01

    The species described as Longistriata fortuita Freitas, Lent, and Almeida, 1937 is here redescribed from new material collected from the type host, Holochilus chacarius balnearum Thomas, and the type locality, San Martín del Tabacal, Salta, Argentina. Neotypes are designed for the species since the type material deposited by the authors is lost. The original description did not include the synlophe or the female and both are here described. Several characters of the synlophe as the number of ridges (14-19), the ridges continuous and all around body, and the presence of a gradient of size of the ridges allow us to place the species within the Heligmonellidae, Nippostrongylinae. The species possesses a unique combination of characters as the synlophe having a carene together with characters of the caudal bursa as the pattern 1-3-1 and the strong development of the dorsal lobe and ray, which precludes its inclusion in any known genus of Nippostrongylinae. A new genus Mazzanema n. gen. is proposed for it, resulting in the new combination Mazzzanema fortuita n. comb.

  18. An Excel-lent Card Trick

    ERIC Educational Resources Information Center

    Zullo, Holly S.

    2011-01-01

    Card tricks based on mathematical principles can be a great way to get students interested in exploring some important mathematical ideas. In this article, the author discusses a simple spreadsheet implementation that shows students why the card trick works and allows them to explore several variations. As an added bonus, students are introduced…

  19. March 30, 1993 Letter to Dr. Lents

    EPA Pesticide Factsheets

    This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Policy and Guidance Database available at www2.epa.gov/title-v-operating-permits/title-v-operating-permit-policy-and-guidance-document-index. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  20. An Excel-lent Card Trick

    ERIC Educational Resources Information Center

    Zullo, Holly S.

    2011-01-01

    Card tricks based on mathematical principles can be a great way to get students interested in exploring some important mathematical ideas. In this article, the author discusses a simple spreadsheet implementation that shows students why the card trick works and allows them to explore several variations. As an added bonus, students are introduced…

  1. Etude de l'effet de la température de dépôt ou de recuit sur la formation de l'interface Au/GaSb(100) par diffraction d'électrons lents et spectroscopies d'électrons Auger ou de pertes d'énergies

    NASA Astrophysics Data System (ADS)

    Rouanet, M.; Oueini, W.; Nouaoura, M.; Bertru, N.; Bonnet, J.; Lassabatere, L.

    1995-05-01

    Auger electron spectroscopy (AES), energy electron loss spectroscopy (EELS) and low energy electron diffraction (LEED) are used to precise the interaction of gold with GaSb(100) surfaces grown on GaSb substrates by molecular beam epitaxy (MBE). After the growth, the GaSb layers, produced in the laboratory, were transferred by the mean of an ultra vacuum lock chamber, into an other ultra vacuum devoted to the deposit of gold and to the physical studies. Measurements were first performed on the clean surfaces and then on surfaces covered by increasing amounts of gold (6 × 10^{13} 1.8 × 10^{16} atoms cm^{-2}) deposited on substrates brought at room temperature or at low temperature (220 K). The samples were then studied during the annealing up to 520 K. The results show, at the beginning of the deposition, gold was adsorbed on the MBE GaSb(100) surface. When the gold coverage increases and becomes higher than 10^{15} atomes cm^{-2}, Au diffuses into the bulk and forms alloys. Nous étudions par spectroscopie d'électrons Auger (SEA), spectroscopie de pertes d'énergies d'électrons lents (SPEEL) et diffraction d'électrons lents (DEL), l'adsorption de l'or sur des surfaces (100) de couches de GaSb obtenues au laboratoire par épitaxie par jets moléculaires (EJM) sur des substrats de GaSb, puis transférées pour dépôt et étude dans l'enceinte à ultravvide de dépôt métallique par l'intermédiaire d'un sas sous ultravide. Les mesures sont effectuées avant et après dépôts d'or (6 × 10^{13} 1,8 × 10^{16} atomes cm^{-2}) réalisés sur un substrat à la température ambiante ou refroidi à 220 K. Les échantillons sont ensuite étudiés pendant lerecuit jusqu'à 520 K. Les résultats obtenues montrent que l'or, dans un premier temps s'adsorbe sur la surface, puis, lorsque le dépôt augmente, diffuse dans le volume du matériau. cette diffusion, qui peut s'acompagner de la formation d'alliages, n'est cependant notable dans la gamme de température utilis

  2. Observación de lentes gravitatorias con ALMA

    NASA Astrophysics Data System (ADS)

    Bonilla, A.; Toloza, O.; Fuentes, I.; Motta, V.

    Gravitational lensing is a fundamental tool for cosmology. A recent instru- ment which will provide more information for models of these objects is ALMA. Our goal is to select lens candidates to observe with ALMA and then model them using GravLens Software. We had selected 12 quadruple images systems from the CASTLES database, which show a high probabil- ity of observing extended sources in the submillimetric range. These new data will allow us to improve existing models. FULL TEXT IN SPANISH

  3. Contrast sensitivity evaluation of aspheric and spherical intraocular lenses 2 years after implantation.

    PubMed

    Caporossi, Aldo; Casprini, Fabrizio; Martone, Gianluca; Balestrazzi, Angelo; Tosi, Gian Marco; Ciompi, Leonardo

    2009-07-01

    To compare the quality of vision with aspheric and spherical intraocular lenses (IOLs) in pseudophakic patients after long-term follow-up. Two hundred eyes of 100 patients with bilateral cataracts were randomly assigned to receive spherical (Acrysof SN60AT [Alcon Laboratories Inc] or Sensar AR40e [Advanced Medical Optics Inc]) or aspheric IOLs (Acrysof SN60WF [Alcon] or Tecnis Z9000 [Advanced Medical Optics]). Ophthalmologic examination, including best spectacle-corrected visual acuity (BSCVA), pupil size, ocular dominance, contrast sensitivity under mesopic and photopic conditions, and wavefront analysis, was performed 2 months and 1 and 2 years after surgery. No statistically significant differences among the four groups in terms of age, pupil diameter, postoperative BSCVA, comeal spherical aberration, and posterior capsular opacification were noted. At all followup examinations, contrast sensitivity results showed no significant differences between the two aspheric IOLs at all spatial frequencies. Under photopic conditions, significant differences (P<.05) between spherical and aspheric IOLs were detected for spatial frequencies of 12 and 18 cycles per degree (cpd) at 2 months and 2 years and 12 cpd at 1 year. Under mesopic conditions, significant differences (P<.05) were detected between spherical and aspheric IOLs for all spatial frequencies at 2 months; all spatial frequencies except 18 cpd at 1 year; and spatial frequencies of 3, 12, and 18 cpd at 2 years. In addition, aspheric IOLs had statistical reductions in total spherical aberration at all follow-up examinations (P<.01). This study confirms that implantation of a modified aspheric IOL improves functional visual performance at 2 years postoperative.

  4. Nd:YAG laser capsulotomy rates following implantation of square-edged intraocular lenses: polymethyl methacrylate versus silicone versus acrylic.

    PubMed

    Ram, Jagat; Kumar, Sunil; Sukhija, Jaspreet; Severia, Saurabh

    2009-04-01

    To study the influence of square-edged intraocular lenses (IOLs) on the development of posterior capsule opacification (PCO) and the requirement for laser capsulotomy. Retrospective study. Three hundred seventy-seven eyes of 377 patients were included. All these patients underwent phacoemulsification and implantation of square polymethyl methacrylate (PMMA) (Aurolab), silicone (Tecnis Z9000), acrylic hydrophobic (AcrySof MA60AC and Sensar Optiedge), or acrylic hydrophilic (Akreos Adapt) IOLs with a minimum of 2 years' follow-up. Only those cases in which Nd:YAG laser capsulotomy had been performed for visually significant PCO were evaluated. Three hundred seventy-seven eyes of 377 patients were included in the study. Follow-up duration ranged from 24 to 54 (mean 40.27, SD 8.42) months. The incidence of PCO requiring Nd:YAG laser capsulotomy was found to be significantly less in the silicone lens group: 1.4% as compared with an incidence of 11.7% in the PMMA lens group (p = 0.018). In the square-edged acrylic group, visually significant PCO requiring Nd:YAG laser capsulotomy was observed in 3.6%, 4.8%, and 6.8% of eyes implanted with AcrySof MA60AC, Sensar Optiedge, and Akreos Adapt IOLs, respectively. In 5 of the 7 eyes (71.4%) exhibiting PCO in the PMMA group, the condition developed within the first 6 months. In the silicone and acrylic group, development of PCO was delayed. The rate of visually significant PCO as well as the need for Nd:YAG laser capsulotomy is influenced by IOL biomaterial in addition to square edge. It is significantly delayed with square-edged foldable acrylic and silicone IOLs compared with square-edged PMMA IOLs.

  5. Canibalismo Extremo y Lente Gravitacional Intensa en el Cúmulo de Galaxias Abell 3827

    NASA Astrophysics Data System (ADS)

    Díaz, R. J.; West, M.; Bergmann, M.; Carrasco, E. R.; Gomez, P.; Lee, H.; Miller, B.; Turner, J.

    Abell 3827 is one of the most massive known clusters and at its center we observe an extreme example of galactic canibalism: a super giant elliptical galaxy in its formation process, devoring five massive galaxies at the same time. Using high spatial resolution Gemini+GMOS imagery and multi-object spectroscopy, we derived the redshift (z=0.099) and the radial velocity dispersion of the 55 brightest galaxies in the cluster central region (1134 +- 125 km/s). The estimated virial mass is ~ 1E14 M(sun) inside a radius of 300 kpc of the cluster center. We have also found features corresponding to a strong gravitational lense, four anular features arranged in an Einstein Ring from a galaxy (z=0.2) at double redshift than the cluster, and a fifth arclet feature corresponding to the lensed light of a farther galaxy (z=0.4). The possible Einstein Ring is of small angular size and the gravitational lense morphology would confirm that the cluster is indeed very massive and dense. FULL TEXT IN SPANISH.

  6. School-Wide Success Builds on 'ExCEL'lent Program

    ERIC Educational Resources Information Center

    Boutelle, Marsha

    2008-01-01

    It's not often that the goals of closing the achievement gap, providing professional development opportunities to teachers, and benefiting children by using innovative and effective instructional methods coincide. But at Sutterville Elementary School in Sacramento, CA, they do. This article describes the School-Wide Success (SWS) program, its…

  7. 12 CFR 7.1003 - Money lent at banking offices or at other than banking offices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...(j) and 12 CFR 5.30, “money” is deemed to be “lent” only at the place, if any, where the borrower in... by a borrower in person at a place that is not the bank's main office and is not licensed as a branch without violating 12 U.S.C. 36, 12 U.S.C. 81 and 12 CFR 5.30, provided that a third party is used...

  8. Biology of Triatoma carcavalloi Jurberg, Rocha & Lent, 1998 under laboratory conditions.

    PubMed

    Cardozo-de-Almeida, Margareth; Neves, Simone Caldas Teves; Almeida, Carlos Eduardo de; Lima, Nathanielly Rocha Casado de; Oliveira, Maria Luiza Ribeiro de; Santos-Mallet, Jacenir Reis dos; Gonçalves, Teresa Cristina Monte

    2014-01-01

    Triatoma carcavalloi is a wild species that is found in sympatry with Triatoma rubrovaria and Triatoma circummaculata, which are vectors of Trypanosoma cruzi currently found in rural areas of Rio Grande do Sul, Brazil. Fertility was assessed and to determine the incubation period, the eggs were observed until hatching. The first meal was offered to 1st stage nymphs. The intermolt period was also determined. The number of blood meals was quantified at each nymphal stage and the resistance to fasting as the period between ecdysis and death. Mortality was assessed and longevity was determined by recording the time that elapsed from molting to the adult stage and until death. The developmental cycle was assessed by recording the length in days of each stage from molting to adult hood. The average incubation period was 22.7 days. The average first meal occurred 3.1 days after hatching. The 5th stage nymph to adult intermolting period was the longest at 193.4 days. The average number of feedings during nymphal development was 13.4. The resistance to fasting assay indicated that the 3rd, 4th and 5th stage nymphs presented higher resistance than did adults. The highest mortality rate was observed in the 3rd stage nymphs (22.2%). The average length of adult survival was 25.6 weeks, and the average total life cycle lasted 503.4 days. This study is the first report on the biology of T. carcavalloi that fed on mice. The presented findings expand the bionomic knowledge of these species.

  9. "I Gave up MySpace for Lent": New Teachers and Social Networking Sites

    ERIC Educational Resources Information Center

    Kist, William

    2008-01-01

    This Digital Literacies column describes the dilemma many new teachers feel as their uses of social networking sites pose conflicts with institutional cautions regarding educators' participation in these kinds of online activities. Pre-service teachers discuss the challenges of marrying their own out-of-school literacies to mandated professional…

  10. "I Gave up MySpace for Lent": New Teachers and Social Networking Sites

    ERIC Educational Resources Information Center

    Kist, William

    2008-01-01

    This Digital Literacies column describes the dilemma many new teachers feel as their uses of social networking sites pose conflicts with institutional cautions regarding educators' participation in these kinds of online activities. Pre-service teachers discuss the challenges of marrying their own out-of-school literacies to mandated professional…

  11. School-Wide Success Builds on 'ExCEL'lent Program

    ERIC Educational Resources Information Center

    Boutelle, Marsha

    2008-01-01

    It's not often that the goals of closing the achievement gap, providing professional development opportunities to teachers, and benefiting children by using innovative and effective instructional methods coincide. But at Sutterville Elementary School in Sacramento, CA, they do. This article describes the School-Wide Success (SWS) program, its…

  12. Visual outcome and optical quality after bilateral implantation of aspheric diffractive multifocal, aspheric monofocal and spherical monofocal intraocular lenses: a prospective comparison

    PubMed Central

    Ye, Pan-Pan; Li, Xia; Yao, Ke

    2013-01-01

    AIM To evaluate the visual function after bilateral implantation of aspheric diffractive multifocal Tecnis ZMA00, aspheric monofocal ZA9003 versus spherical monofocal Akreos Adapt intraocular lenses (IOLs). METHODS Tecnis ZMA00, Tecnis ZA9003 or Akreos Adapt IOLs were bilaterally implanted in 180 eyes from 90 patients. The following parameters were assessed 3 months postoperatively: monocular and binocular uncorrected visual acuity (UCVA) and distance-corrected visual acuity (DCVA) for distance, intermediate and near, spherical aberration (SA), contrast and glare sensitivity, near point refractive power, uncorrected and best-corrected near stereoscopic acuity (NSA). Patient satisfaction was assessed by a questionnaire. RESULTS Three months postoperatively, the monocular and binocular UCVA and DCVA at near of Tecnis ZMA00 were significantly better than other two groups. The mean SA for 5.0mm optical zone in Tecnis ZMA00 and Tecnis ZA9003 was significantly lower than that in Akreos Adapt. Mean contrast sensitivity and glare sensitivity were better for Tecnis ZA9003 group than for other two groups. Patients with Tecnis ZMA00 had higher monocular and binocular near point refractive power and uncorrected NSA than monofocal groups. The patients in Tecnis ZMA00 had higher mean values for halo compared with other two groups. CONCLUSION Tecnis ZMA00 provided better near VA and uncorrected NSA and higher near point refractive power than monofocal IOLs and patients were spectacle independent. The IOLs with Tecnis aspheric design improved contrast and glare sensitivity. Patients with Tecnis ZMA00 reported more disturbances on visual phenomena of halo. PMID:23826522

  13. Acarbose, lente carbohydrate, and prebiotics promote metabolic health and longevity by stimulating intestinal production of GLP-1

    PubMed Central

    McCarty, Mark F; DiNicolantonio, James J

    2015-01-01

    The α-glucosidase inhibitor acarbose, which slows carbohydrate digestion and blunts postprandial rises in plasma glucose, has long been used to treat patients with type 2 diabetes or glucose intolerance. Like metformin, acarbose tends to aid weight control, postpone onset of diabetes and decrease risk for cardiovascular events. Acarbose treatment can favourably affect blood pressure, serum lipids, platelet aggregation, progression of carotid intima-media thickness and postprandial endothelial dysfunction. In mice, lifetime acarbose feeding can increase median and maximal lifespan—an effect associated with increased plasma levels of fibroblast growth factor 21 (FGF21) and decreased levels of insulin-like growth factor-I (IGF-I). There is growing reason to suspect that an upregulation of fasting and postprandial production of glucagon-like peptide-1 (GLP-1)—stemming from increased delivery of carbohydrate to L cells in the distal intestinal tract—is largely responsible for the versatile health protection conferred by acarbose. Indeed, GLP-1 exerts protective effects on vascular endothelium, the liver, the heart, pancreatic β cells, and the brain which can rationalise many of the benefits reported with acarbose. And GLP-1 may act on the liver to modulate its production of FGF21 and IGF-I, thereby promoting longevity. The benefits of acarbose are likely mimicked by diets featuring slowly-digested ‘lente’ carbohydrate, and by certain nutraceuticals which can slow carbohydrate absorption. Prebiotics that promote colonic generation of short-chain fatty acids represent an alternative strategy for boosting intestinal GLP-1 production. The health benefits of all these measures presumably would be potentiated by concurrent use of dipeptidyl peptidase 4 inhibitors, which slow the proteolysis of GLP-1 in the blood. PMID:25685364

  14. New record and cytogenetic analysis of Psammolestes tertius Lent & Jurberg, 1965 (Hemiptera, Reduviidae, Triatominae) from Bahia State, Brazil.

    PubMed

    Oliveira, J; Alevi, K C C; Fonseca, E O L; Souza, O M F; Santos, C G S; Azeredo-Oliveira, M T V; da Rosa, J A

    2016-06-20

    This paper reports on the first occurrence of Psammolestes tertius in the Chapada Diamantina region, located in the city of Seabra, Bahia State, in northeastern Brazil. Following an active search, 24 P. tertius specimens were collected from Phacellodomus rufifrons (rufous-fronted thornbird) nests. The insects did not present any symptoms of infection by Trypanosoma cruzi. P. tertius males were cytogenetically analyzed, and the results were compared with those of other specimens from the Brazilian State of Ceará. Triatomines from both locations presented the same cytogenetic characteristics: 22 chromosomes, little variation in the size of the autosomes, Y chromosomes that were larger than the X chromosomes, a chromocenter formed only by the sex chromosomes during prophase, and autosomes lacking constitutive heterochromatin. However, it is important to note that this species shows intraspecific chromosomal variation. In light of the results obtained, it is recommended that more studies be performed to characterize P. tertius. These studies will be particularly helpful in understanding this species in ecological, biological, biogeographical, and phylogenetic terms.

  15. Aspheric versus Spherical Posterior Chamber Intraocular Lenses

    PubMed Central

    Jafarinasab, Mohammad-Reza; Feizi, Sepehr; Baghi, Ahmad-Reza; Ziaie, Hossein; Yaseri, Mehdi

    2010-01-01

    Purpose To compare spherical aberration and contrast sensitivity function following implantation of four different foldable posterior chamber intraocular lenses (IOLs), namely Sensar, Akreos AO, Tecnis, and AcrySof IQ. Methods In this randomized clinical trial, 68 eyes of 68 patients with senile cataracts underwent phacoemulsification and IOL implantation with Sensar (n=17), Akreos AO (n=17), Tecnis (n=17), or AcrySof IQ (n=17). Uncorrected visual acuity (UCVA) and best spectacle-corrected visual acuity (BSCVA), spherical aberration and contrast sensitivity function (CSF) were compared among the study groups, 3 months after surgery. Results There was no significant difference between the study groups in terms of age (P = 0.21). Mean postoperative BSCVA with Sensar, Akreos AO, Tecnis, and AcrySof IQ was 0.15±0.10, 0.12±0.9, 0.08±0.08, and 0.08±0.07 logMAR, respectively (P=0.08). Spherical aberration measured over a 4 mm pupil was significantly higher with Sensar and Akreos AO than the two other IOLs. The difference between Tecnis and AcrySof IQ was significantly in favor of the former IOL. Over a 6 mm pupil, spherical aberrations were comparable with Sensar and Akreos AO, furthermore spherical aberration was also comparable among eyes implanted with Akreos AO, AcrySof IQ, and Tecnis. Sensar yielded significantly inferior results as compared to Acrysof IQ and Tecnis. CSF with Sensar was inferior to the three aspheric IOLs at the majority of spatial frequencies. Tecnis yielded significantly better mesopic CSF at 1.5 and 3 cycles per degree spatial frequencies. Conclusion Tecnis and AcrySof IQ provided significantly better visual function as compared to Sensar and Akreos AO, especially with smaller pupil size. However, this difference diminished with increasing pupil size. PMID:22737364

  16. The New World filarial genus Molinema Freitas & Lent, 1939 (Nematoda: Onchocercidae), with a description of four new species parasitic in the Echimyidae (Rodentia).

    PubMed

    Guerrero, R; Bain, O

    2001-03-01

    Four new species of Molinema (Filarioidea: Onchocercidae), parasites of echimyid rodents in South America, are described: M. algardneri n. sp. from Proechimys amphichoricus, M. barbarae n. sp. from P. cayennensis, both in Venezuela (Rio Negro and Cerro La Neblina, respectively), M. peruviensis n. sp. from P. steerei in Peru (lower Urubamba), and M. nattereri n. sp. (= Filaria diacantha Molin, 1858 pro parte) from Echimys ? didelphoides (= Loncheres rufa) in Brazil (Matto Grosso). They differ from each other and from the previously described species in the following characters: flat or concave head, cephalic ratio (distance between cephalic papillae in median view/lateral view), size and shape of the buccal capsule, length of the oesophagus, cuticular ornamentation of the female body, length of the ovijector, thick or slim female tail, area rugosa, long or short filament in the left spicule, heel in the right spicule, respective position of postcloacal papilla pairs 5 and 6, shape of the caudal lappets, terminal point present or absent, and the microfilariae. Molinema, which belongs to the worldwide Dipetalonema line, is distributed in two of the ten families of the Caviomorpha (South American Hystrichognathi have extended their distribution in South America since the early Oligocene). Nine species are parasitic in the Echimyidae (suborder Caviida); they have a short oesophagus and a complete or reduced set of precloacal papillae (four or three pairs). Two species are parasitic in the Erethizontidae (Erethizontida) and might be more primitive in having a well-developed oesophagus. However, the type-species M. diacantha, of which a female specimen was studied, has a large buccal capsule and has evolved concave head, while M. arbuta has a reduced buccal capsule and primitive flat head. This last species is a parasite of a Nearctic porcupine and probably represents a small line of Molinema which migrated to the north with its hosts when communications were established between the two American continents 3 mya (Pleistocene). M. sprenti, the unique parasite of the Castoridae in North America, is considered to be derived from this group by capture.

  17. A comparison of mesopic visual acuity and objective visual quality following cataract surgery with hydrophobic acrylic intraocular lenses.

    PubMed

    Beiko, George Hh; Gostimir, Miso; Haj-Ahmad, Lila

    2017-01-01

    To evaluate mesopic visual acuity and visual quality as measured by objective scatter index (OSI) in pseudophakic eyes with long-term follow-up after implantation of hydrophobic acrylic lenses made from two different lens materials. This study was carried out in a private clinic. This study was an observational cohort study. This pilot study included 181 eyes of 136 patients who had undergone cataract surgery with implantation of monofocal hydrophobic acrylic intraocular lenses (IOLs), either Alcon AcrySof (82 eyes) or Abbott Medical Optics' Tecnis (99 eyes). The monocular corrected distance visual acuity (CDVA) of the subjects was recorded under mesopic room illumination and OSI was measured by an optical quality analysis system using double-pass wavefront method. Mean follow-up duration was 60.07±18.82 months. Eyes implanted with Tecnis IOLs had statistically significantly better mesopic CDVA (0.08±0.08) compared to those implanted with AcrySof IOLs (0.11±0.07) (P=0.020). Mesopic CDVA of 20/25 or better was found in 79.8% of eyes in the Tecnis group compared to 62.2% of eyes in AcrySof group. Similarly, OSI was also found to be statistically significantly better for Tecnis IOLs compared to AcrySof IOL group (mean OSI, Tecnis: 1.65±0.92, AcrySof: 2.01±1.36; P=0.033). When glaucomatous eyes were excluded, OSI was still significantly better (P=0.028) in the Tecnis IOL group. The eyes implanted with Tecnis IOLs showed better long-term optical performance in terms of both OSI and mesopic visual acuity in comparison to those with AcrySof IOLs.

  18. ?La Maétresse dit que je suis lent?: Représentation de l'école française dans le discours d'élèves immigrés

    NASA Astrophysics Data System (ADS)

    Vasquez, Ana; Proux, Michelle B.

    1984-06-01

    The difficulties of immigrant children at school have generally been studied with the emphasis either on their deficiencies or on the schemes which they devise to enable them to adapt. The study which is presented here, however, aims at a radically different approach by viewing the problem within the theoretical framework of transculturation and by examining the way in which the pupils themselves perceive the French school system. A study is made of the outcome of 101 interviews which were conducted in their mother tongue with Spanish- or Portuguese-speaking boys and girls aged between 10 and 17 years old. On the basis of statistical analysis by computer, indices were formulated with the intention of establishing (a) the relationship between the researcher and the subject during the interview; (b) the links between the subject as an individual and his/her peer-group (`me' — `us'); (c) his/her perception of `others'; and (d) the way in which he/she relates to his/her experience (as something to be positively accepted — or to be suffered; `active' or `passive'). Keywords illustrate and underline the difficulties encountered both by pupils and by the school to grasp the idea of time norms as a cultural shaping and to perceive how relative they are.

  19. The exotic palm Roystonea oleracea (Jacq.) O.F. Cook as a rural biotype for Rhodnius neglectus Lent, 1954, in Caçu, State of Goiás.

    PubMed

    Vianna, Elisa Neves; de Andrade, Andrey José; Dias, Fernando Braga Stehling; Diotaiuti, Liléia

    2014-01-01

    Rhodnius neglectus is a triatomine that colonizes different palm species. In this study, we aimed to describe the presence of this triatomine bug in the royal palms (Roystonea oleracea) in a rural region of the State of Goiás. Palm infestation was investigated by dissecting the palms or by using live-bait traps. Two palm trees were infested by R. neglectus negative for Trypanosoma cruzi, the etiological agent for Chagas disease. In the study area, R. neglectus is frequently found in households. The adaptation of this species to palm trees introduced in Brazil for landscaping purposes poses another challenge for controlling the vectors of Chagas disease.

  20. El rol de Ia colaboracion y el Modelo de Aprendizaje Basado en Proyectos (ABPr) mediante el lente de la Teoria de Actividad (CHAT): un estudio de caso con estudiantes de 9no grado

    NASA Astrophysics Data System (ADS)

    Delgado, Isabel C.

    Los modelos de eensenanza y aprendizaje constructivistas conceptualizan el aprendizaje como un proceso activo. El modelo de Aprendizaje Basado en Proyectos (ABPr) se distingue por una serie de componentes, entre los cuales se destaca el aspecto colaborativo y cooperativo como un reto al momento de su implantacion. Son pocas las investigaciones que se concentran en este aspecto del modelo. En este estudio, se analizaron las diversas interacciones que surgen durante la implantacion de una unidad curricular sobre el tema de Geologia de Puerto Rico, la cual se diseno con el modelo ABPr cuyo enfoque es orientacion a proyectos. Particularmente, se examinaron las interacciones sociales que surgen entre los pares y entre pares y docente durante el proceso de planificacion y desarrollo de los productos finales, al igual que las interacciones entre los estudiantes y el material didactico en estas etapas del modelo. La investigacion es de tipo cualitativo e incorpora como diseno el estudio de caso. Las diversas interacciones constituyen la unidad de analisis. En el estudio participaron 19 estudiantes de 9no grado, a quienes se organizaron en 5 grupos colaborativos por temas de interes (Pangea, Placas tectonicas, Volcanes, Tsunamis y Terremotos). Las tecnicas que se utilizaron para recopilar los datos fueron: observaciones participativas, grupos focales y analisis de documentos (cuadernos reflexivos y respuestas de los estudiantes a la pregunta central del proyecto). Para el analisis de los datos se aplico la teoria de actividad (CHAT) que concentra la unidad de analisis en la actividad humana en un contexto particular. Los resultados del estudio senalan que las interacciones entre pares, entre pares y docente, asi como entre estudiantes y material didactico son fundamentales en el proceso de aprendizaje. Una mayor interaccion entre pares durante las etapas de planificar y desarrollar los productos finales de la unidad, promueve una mejor comprension de los conceptos de la unidad, segun evidencia los productos finales del ABPr. La interaccion con el docente es muy importante para mediar los conflictos y desacuerdos que surgen como parte de las interacciones entre pares. Por lo tanto, el uso de diversas estrategias de andamiaje por parte del docente durante las reuniones de los grupos colaborativos es esencial para el exito del modelo ABPr.

  1. Change in efficiency of aspheric intraocular lenses based on pupil diameter.

    PubMed

    Eom, Youngsub; Yoo, Eunjoo; Kang, Su-Yeon; Kim, Hyo-Myung; Song, Jong-Suk

    2013-03-01

    To measure the effect of spherical aberration correction by aspheric intraocular lenses (IOLs) based on pupil diameter, and to determine the minimum pupil diameter for each aspheric IOL. Retrospective cross-sectional study. Eight-six patients (169 eyes) who were implanted with a HOYA AF-1 NY-60 (HOYA Corporation) or Tecnis ZCB00 1-piece IOL (Abbott Medical Optics Inc) were enrolled. Ocular, corneal, and internal spherical aberrations were measured at the 1-month postoperative visit using the Wavefront Analyzer KR-1W (Topcon). Minimum pupil diameter, which is required for each aspheric IOL to be effective, was calculated using a regression equation. The mean value of internal spherical aberration of the Tecnis ZCB00 group (-0.09 ± 0.094 μm) was lower than that of the HOYA NY-60 group (-0.05 ± 0.072 μm) (P = .005). The original negative spherical aberrations of the HOYA NY-60 (-0.18 μm) were measured at a pupil diameter of 5.6 mm, and for the Tecnis ZCB00 (-0.27 μm) at a pupil diameter of 6.1 mm. The aspheric IOL efficiency dropped to 0% when the pupil diameter was 3.47 mm for the Tecnis ZCB00 group and 3.71 mm for the HOYA NY-60 group. When the pupil diameters of patients are smaller than 3.4 mm for the Tecnis ZCB00 and 3.7 mm for the HOYA NY-60, the spherical aberration correction using these aspheric IOLs seems to be ineffective. Approximately 10% of the eyes showed smaller pupil size than the minimum effective diameter under mesopic conditions. Copyright © 2013 Elsevier Inc. All rights reserved.

  2. 12 CFR 9.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... which deposits are received, or checks paid, or money lent. (k) Trust representative office means an... property. This list is illustrative and not comprehensive. Other activities may also be “ancillary... received, or checks paid, or money lent....

  3. Effect of Spherical Aberration on the Optical Quality after Implantation of Two Different Aspherical Intraocular Lenses

    PubMed Central

    Kovács, Illés; Vécsei-Marlovits, Pia Veronika

    2017-01-01

    Purpose To compare the effect of spherical aberration on optical quality in eyes with two different aspherical intraocular lenses. Methods 120 eyes of 60 patients underwent phacoemulsification. In patients' eyes, an aberration-free IOL (Aspira-aA; Human Optics) or an aberration-correcting aspherical IOL (Tecnis ZCB00; Abott Medical Optics) was randomly implanted. After surgery, contrast sensitivity and wavefront measurements as well as tilt and decentration measurements were performed. Results Contrast sensitivity was significantly higher in eyes with Aspira lens under mesopic conditions with 12 cycles per degree (CPD) and under photopic conditions with 18 CPD (p = 0.02). Wavefront measurements showed a higher total spherical aberration with a minimal pupil size of 4 mm in the Aspira group (0.05 ± 0.03) than in the Tecnis group (0.03 ± 0.02) (p = 0.001). Strehl ratio was higher in eyes with Tecnis (0.28 ± 0.17) with a minimal pupil size larger than 5 mm than that with Aspira (0.16 ± 0.14) (p = 0.04). In pupils with a minimum diameter of 4 mm spherical aberration had a significant effect on Strehl ratio, but not in pupils with a diameter less than 4 mm. Conclusions Optical quality was better in eyes with the aberration-correcting Tecnis IOL when pupils were large. In contrast, this could not be shown in eyes with pupils under 4 mm or larger. This trial is registered with Clinicaltrials.gov NCT03224728. PMID:28900544

  4. Early clinical experience with a new preloaded one-piece intraocular lens in paediatric cataract surgery.

    PubMed

    Gosling, D B; Chan, T K J

    2016-09-01

    PurposeTo report the clinical experience of using the Tecnis PCB00 (Abbott Medical Optics, Santa Ana, CA, USA) preloaded one-piece intraocular lens (IOL) in the setting of a tertiary referral centre for paediatric cataract.MethodsA retrospective case note review of all paediatric cataract surgeries using the Tecnis PCB00 IOL, at a single UK paediatric ophthalmology department.ResultsNine eyes in seven patients received the IOL between December 2014 and January 2016. All patients underwent lens aspiration and insertion of the IOL 'in the bag.' The indications for surgery included developmental cataract (8/9) and traumatic cataract (1/9). Mean age at the time of surgery was 7 years (range 2-14). The median improvement in logMAR best-corrected visual acuity was 0.475 (range 0.250-1.500). The mean follow-up duration was 5 months (range 1-13). No operative or post-operative complications occurred as a result of using the device.ConclusionThe Tecnis PCB00 preloaded IOL appears to be a safe and effective device in treating paediatric cataract.

  5. Lack of effect of intraocular lens asphericity on visual performance with acrylic intraocular lenses.

    PubMed

    Muñoz, Gonzalo; Albarrán-Diego, César; Galotto, M Ángeles; Pascual, Javier; Ferrer-Blasco, Teresa

    2011-01-01

    To determine whether implantation of acrylic intraocular lens (IOL) with aspheric design (Tecnis Z9003, AMO) results in improved visual acuity or contrast sensitivity compared with conventional spherical acrylic IOL (AR40e, AMO). In an intraindividual randomized prospective study of 60 patients with bilateral cataract, the Tecnis Z9003 IOL was compared with the AR40e IOL. Ocular aberrations for a 4.0-mm pupil and 6.0-mm pupil were measured with a Hartmann-Shack aberrometer. Quality of vision was measured using visual acuity and contrast sensitivity under mesopic and photopic conditions. Eyes with the Tecnis Z9003 IOL had significantly less spherical aberration and greater Strehl ratio after surgery, showing a better optical quality in comparison with the standard spherical IOL. However, visual acuity and both mesopic and photopic contrast sensitivity were not significantly different between the groups. The significantly better optical quality achieved with the aspheric acrylic IOL design did not result in improved visual acuity or contrast sensitivity in comparison with a conventional spherical acrylic IOL.

  6. Power-Aware Cognitive Packet Networks

    DTIC Science & Technology

    2005-04-01

    Power-Aware Cognitive Packet Networks Erol Gelenbe Dennis Gabor Chair Ricardo Lent Research Fellow Department of Electrical and Electronic...intelligent distribution of energy consumption in the network Power-Aware Cognitive Packet Networks Erol Gelenbe Dennis Gabor Chair Ricardo Lent

  7. Test of a Social Cognitive Model of Work Satisfaction in Teachers

    ERIC Educational Resources Information Center

    Duffy, Ryan D.; Lent, Robert W.

    2009-01-01

    Lent and Brown [Lent, R. W., & Brown, S. D. (2006). "Integrating person and situation perspectives on work satisfaction: A social-cognitive view." "Journal of Vocational Behavior,69", 236-247] recently proposed an integrative model of work satisfaction linked to social cognitive career theory. The model posits that work satisfaction is predicted…

  8. The Changing Nature of External Threats, Economic and Political Imperatives, and Seamless Logistics

    DTIC Science & Technology

    1997-07-01

    tank to defeat German armor. The US Sher- 84 AIRPOWER JOURNAL SUMMER 1997 The GBU-28 Bunker Buster Program is an excel lent case in point. One of the...reduc ing cycle time is criti­ cal. The GBU-28 Bunker Buster Program is an ex cel lent case in point. During Opera tion De sert Storm, a new weapon

  9. Social Cognitive Influences on Mexican Americans' Career Choices across Holland's Themes

    ERIC Educational Resources Information Center

    Flores, Lisa Y.; Robitschek, Chris; Celebi, Elif; Andersen, Christie; Hoang, Uyen

    2010-01-01

    This study examined several propositions of social cognitive career theory ([Lent et al., 1994] and [Lent et al., 2000]) with a sample of 393 Mexican American college students. It was hypothesized that person input (i.e., age) and background contextual variables (i.e., Anglo orientation, Mexican orientation, familism, instrumentality, and…

  10. A Social Cognitive Perspective on Well-Being in Educational and Work Settings: Cross-Cultural Considerations

    ERIC Educational Resources Information Center

    Sheu, Hung-Bin; Lent, Robert W.

    2009-01-01

    The article gives an overview of a social cognitive perspective on psychosocial well-being and adjustment (Lent, 2004), along with a model of educational and work-related satisfaction (Lent & Brown, 2006) that has been derived from it. The theoretical perspective integrates cognitive, behavioural, social, and personality variables hypothesized to…

  11. Test of a Social Cognitive Model of Work Satisfaction in Teachers

    ERIC Educational Resources Information Center

    Duffy, Ryan D.; Lent, Robert W.

    2009-01-01

    Lent and Brown [Lent, R. W., & Brown, S. D. (2006). "Integrating person and situation perspectives on work satisfaction: A social-cognitive view." "Journal of Vocational Behavior,69", 236-247] recently proposed an integrative model of work satisfaction linked to social cognitive career theory. The model posits that work satisfaction is predicted…

  12. Toric intraocular lens orientation and residual refractive astigmatism: an analysis

    PubMed Central

    Potvin, Rick; Kramer, Brent A; Hardten, David R; Berdahl, John P

    2016-01-01

    Purpose To analyze intraocular lens (IOL) orientation data from an online toric back-calculator (astigmatismfix.com) for determining if differences were apparent by lens type. Methods A retrospective review of astigmatismfix.com toric back-calculations that included IOL identification and intended orientation axis. Results Of 12,812 total validated calculation records, 8,229 included intended orientation and lens identification data. Of the latter, 5,674 calculations (69%) involved lenses oriented 5° or more from their intended position. Using estimated toric lens usage data, the percentage of lenses with orientation ≥5° from intended was 0.89% overall, but the percentage varied significantly between specific toric lens brands (P<0.05). The percentage of back-calculations related to lenses that were not oriented as intended was also statistically significantly different by lens brand (P<0.05). When IOLs were misoriented, they were significantly more likely to be misoriented in a counterclockwise direction (P<0.05). This was found to be due to a bias toward counterclockwise orientation observed with one specific brand, a bias that was not observed with the other three brands analyzed here. Conclusion The percentage of eyes with lens orientation ≥5° from intended in the Toric Results Analyzer data set was <1% of toric IOLs in general, with the relative percentage of Tecnis® Toric IOLs significantly higher than AcrySof® Toric IOLs. Both of these had higher rates than the Staar® Toric and Trulign® Toric lenses, with the availability of higher Tecnis and AcrySof cylinder powers a likely contributing factor. The AcrySof Toric IOL appears to be less likely than the Tecnis Toric IOL to cause residual astigmatism as a result of misorientation. The Tecnis Toric IOL appears more likely to be misoriented in a counterclockwise direction; no such bias was observed with the AcrySof Toric, the Trulign® Toric, or the Staar Toric IOLs. PMID:27703323

  13. Extended depth of focus intraocular lens: Chromatic performance

    PubMed Central

    Millán, Maria S.; Vega, Fidel

    2017-01-01

    We describe a first-and-second-diffractive-order intraocular lens ((1st,2nd)DIOL) within the class of hybrid refractive-diffractive designs for intraocular lenses (IOLs) and analyse its properties of focus extension and compensation of longitudinal chromatic aberration (LCA), particularly for lenses with low addition. Power, energy efficiency and their wavelength dependence are extended from monofocal IOL and conventional bifocal zeroth-and-first-diffractive-order IOL ((0th,1st)DIOL) to (1st,2nd)DIOL of low addition. Compensation of LCA is experimentally assessed in optical bench through the through-focus energy efficiency of three Tecnis IOLs with red, green and blue illuminations: ZA9003 (monofocal), ZKB00 (bifocal (0th,1st)DIOL with + 2.75 D add) and Symfony ZXR00. We prove Tecnis Symfony ZXR00 IOL can be considered an example of (1st,2nd)DIOL design of low addition, with LCA compensation in both the distance and intermediate foci, whereas the bifocal (0th,1st)DIOL does not compensate in the distance focus. However, the energy efficiency of (1st,2nd)DIOL for wavelengths other than the design wavelength is markedly more asymmetric.

  14. Contact Lenses for Vision Correction

    MedlinePlus

    ... Ophthalmologist Patient Stories Español Eye Health / Glasses & Contacts Contact Lenses Sections Contact Lenses for Vision Correction Contact ... to Know About Contact Lenses Colored Contact Lenses Contact Lenses for Vision Correction Leer en Español: Lentes ...

  15. 1. Historic American Buildings Survey Joseph Hill, Photographer August 1936 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill, Photographer August 1936 FIRST ORIGINAL STORE AND POSTOFFICE, COPY OF AN EARLY PHOTOGRAPH. LENT BY EVELYN S. CRAIG - Jansonist Colony, Colony Store & Post Office, Main & Bishop Hill Streets, Bishop Hill, Henry County, IL

  16. 3. West and south elevations. Joseph Hill, photographer, copied from ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. West and south elevations. Joseph Hill, photographer, copied from photo lent by Evelyn S. Craig. August 1936. - Jansonist Colony, Steeple Building, Main & Bishop Hill Streets, Bishop Hill, Henry County, IL

  17. 2. West and south elevation. Copied from an old print ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. West and south elevation. Copied from an old print by Joseph Hill, lent to survey by Evelyn S. Craig. - Jansonist Colony, Steeple Building, Main & Bishop Hill Streets, Bishop Hill, Henry County, IL

  18. Development of a Compact & Easy-to-Use 3-D Camera for High Speed Turbulent Flow Fields

    DTIC Science & Technology

    2013-12-05

    reconstruction methods (see Herman and Lent [32]) are well-suited for reconstruction given the above constraints. These methods form a linear system of...stereo particle image velocimetry. Experiments in Fluids, 2000. 29(7): p. S70-S77. 3. Brucker, C., D. Hess , and J. Kitzhofer, Single-view...in Aerospace Engineering2011, Auburn University. 32. Herman , G.T. and A. Lent, Iterative reconstruction algorithms. Comput Biol Med, 1976. 6(4): p

  19. Visual acuity and patient satisfaction at varied distances and lighting conditions after implantation of an aspheric diffractive multifocal one-piece intraocular lens

    PubMed Central

    Chang, Daniel H

    2016-01-01

    Purpose The aim of the study is to evaluate the visual acuity and patient satisfaction at varied distances under photopic and mesopic lighting conditions in patients bilaterally implanted with aspheric diffractive multifocal one-piece intraocular lenses. Methods In this retrospective–prospective study, 16 patients with a mean age of 66.2±9.2 years (range: 50–81 years) who had undergone bilateral phacoemulsification surgery with implantation of a Tecnis multifocal one-piece intraocular lens (ZMB00) were evaluated. Monocular and binocular uncorrected and distance-corrected visual acuities were measured at distance (20 ft), intermediate (70–80 cm), and near (35–40 cm) under photopic (85 cd/m2) and mesopic (3 cd/m2) lighting conditions and were compared using the paired t-test. All patients also completed a subjective questionnaire. Results At a mean follow-up of 9.5±3.9 months, distance, near, and intermediate visual acuity improved significantly from preoperative acuity. Under photopic and mesopic conditions, 93.8% and 62.5% of patients, respectively, had binocular uncorrected intermediate visual acuity of 20/40 or better, and 62.5% and 31.3% of patients had binocular uncorrected near visual acuity of 20/20 or better. All patients were satisfied with their overall vision without using glasses and/or contact lenses when compared with before surgery. A total of 87.5% of patients reported no glare and 68.8% of patients reported no halos around lights at night. Conclusion Tecnis multifocal one-piece intraocular lenses provide good distance, intermediate, and near visual acuity under photopic as well as mesopic lighting conditions. High levels of spectacle independence with low levels of photic phenomenon were achieved, resulting in excellent patient satisfaction. PMID:27536061

  20. Predictability and Vector Analysis of Laser In Situ Keratomileusis for Residual Errors in Eyes Implanted With Different Multifocal Intraocular Lenses.

    PubMed

    Santhiago, Marcony R; Ventura, Bruna V; Ghanem, Ramon C; Kara-Junior, Newton; Moraes, Haroldo V; Ghanem, Emir

    2016-11-01

    To investigate potential differences in predictability, efficacy, and safety of corneal excimer laser to correct residual myopia, hyperopia, and astigmatism in eyes previously implanted with multifocal intraocular lenses using distinct optical surfaces and platforms for multifocality. This prospective comparative study included 37 eyes submitted to laser in situ keratomileusis correction for residual errors after implantation of either an apodized diffractive-refractive (Restor) or a full-diffractive (Tecnis) multifocal intraocular lens. Data analysis included investigation of predictability, efficacy, and safety of excimer laser surgery to correct residual errors. A double-angle plot, using vector analysis, was also created to evaluate predictability of astigmatism correction. At 6-month follow-up, statistical analyses revealed a significant improvement when comparing preoperative (0.51 ± 0.25 and 0.44 ± 0.18) and postoperative values (0.17 ± 0.10 and 0.09 ± 0.07) of uncorrected distance visual acuity (P < 0.0001 and <0.0001), preoperative (0.92 ± 0.61 and 1.02 ± 0.45) and postoperative values (0.33 ± 0.23 and 0.19 ± 0.17) of manifest refractive spherical equivalent (P = 0.0006 and <0.0001), and preoperative (-1.08 ± 0.70 and -0.65 ± 0.42) and postoperative values (-0.25 ± 0.28 and -0.14 ± 0.21) of astigmatism (P < 0.0001 and <0.0001) in eyes implanted with Restor and Tecnis, respectively. Vector analysis revealed a predictable correction of astigmatism in all groups. Ninety-two percent of total eyes achieved a manifest refractive spherical equivalent within ±0.5 of emmetropia. Corneal excimer laser refractive surgery seems to be equally effective to correct different residual errors, including astigmatism, in eyes implanted with intraocular lenses with various platforms for multifocality.

  1. Targeted Zinc Delivery: A Novel Treatment for Prostate Cancer

    DTIC Science & Technology

    2010-06-01

    the behavior of cells in a tumor. With this in mind, we examined the ability of Zn to kill PC3 cells grown in a collagen extracellular matrix ECM...Lents NH, Hoyer MK, Jamaluddin N, Klein C, Baldassare J. “Direct intra-tumoral injection of zinc-acetate halts tumor growth in a xenograft model of...C.; Powell, C.R. et al. Br. J. Urol. Int., 2001, 87, 61. 9 (7) Shah MR, Kriedt CL, Lents NH, Hoyer MK, Jamaluddin N, Klein C, Baldassare J

  2. Examining a Model of Life Satisfaction among Unemployed Adults

    ERIC Educational Resources Information Center

    Duffy, Ryan D.; Bott, Elizabeth M.; Allan, Blake A.; Torrey, Carrie L.

    2013-01-01

    The present study examined a model of life satisfaction among a diverse sample of 184 adults who had been unemployed for an average of 10.60 months. Using the Lent (2004) model of life satisfaction as a framework, a model was tested with 5 hypothesized predictor variables: optimism, job search self-efficacy, job search support, job search…

  3. Comparison of glycemic variability associated with insulin glargine and intermediate-acting insulin when used as the basal component of multiple daily injections for adolescents with type 1 diabetes.

    PubMed

    White, Neil H; Chase, H Peter; Arslanian, Silva; Tamborlane, William V

    2009-03-01

    To compare the glucose variability associated with insulin glargine and NPH/Lente insulin used as the basal insulin component of a multiple daily injection (MDI) regimen in pediatric patients with type 1 diabetes. Continuous glucose monitoring data were collected from a subset of patients (n = 90) who agreed to use a continuous glucose monitoring system during an active-controlled, randomized, open-label study evaluating the safety and efficacy of insulin glargine and NPH/Lente insulin used with insulin lispro as part of an MDI regimen. Treatment with insulin glargine resulted in significant reductions in glucose variability as measured by the SD of glucose values (adjusted mean change from baseline to week 24: -13.4 mg/dl [-0.74 mmol/l]; P Lente were not significant. Insulin glargine is associated with greater reductions in glucose variability than NPH/Lente insulin in pediatric patients with type 1 diabetes.

  4. Corporations Can Be Real Angels When It Comes to Financing School Construction.

    ERIC Educational Resources Information Center

    Gonder, Peggy Odell

    1982-01-01

    Details cooperative agreements to finance new schools drawn up by growing school districts in Colorado and the corporations whose activities are responsible for that growth. The developers of an oil shale project and a tract housing project lent school districts money under very favorable terms. (JM)

  5. Portable Language-Independent Adaptive Translation from OCR

    DTIC Science & Technology

    2009-10-15

    cleaning algorithm legitimate ten charecters ere cropped C-H- Alter applying improved rule line cleaning algorithm Text character* ire kept mlecl In...models the document as an undirected weighted graph, a Revised lent hoe detection elgonthm 1 where each connected component is represented by a node

  6. Use of MMLE3 to Determine Lower Order Equivalent Systems in the Time Domain.

    DTIC Science & Technology

    1985-03-01

    responses. One fourth order response defines aircraft longitudinal motion in terms of short period frequency and damping ratio and phugoid frequency... aircraft longitudinal motion. Information 15 .............................a aa.. ... . ... ... With an adequate state-space model and a good initial...equivalent systems for aircraft longitudinal motion. The lower order equiva- lent systems are defined by time delay, equivalent frequency, and equivalent

  7. Feeling the Threat: Stereotype Threat as a Contextual Barrier to Women's Science Career Choice Intentions

    ERIC Educational Resources Information Center

    Deemer, Eric D.; Thoman, Dustin B.; Chase, Justin P.; Smith, Jessi L.

    2014-01-01

    Social cognitive career theory (SCCT; Lent, Brown, & Hackett, 1994, 2000) holds that contextual barriers inhibit self-efficacy and goal choice intentions from points both near and far from the active career development situation. The current study examined the influence of one such proximal barrier, stereotype threat, on attainment of these…

  8. 12 CFR 303.41 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Virgin Islands, and the Northern Mariana Islands at which deposits are received or checks paid or money... relating to transactions in which deposits are received or checks paid or money lent. A messenger service... institution or branch. (d) Home state means the state by which the bank is chartered. (e) Host state means...

  9. The Revenue Imperative: Finding New Funding Streams in the Face of Budget Cuts

    ERIC Educational Resources Information Center

    Fernandez, Kim

    2011-01-01

    By all accounts, 2010 was a watershed year for community colleges. President Obama touted the role these institutions play in putting Americans back to work, and widespread enrollment increases lent credibility to the notion that students at long last are realizing the benefits of two-year quality and value compared with the higher price of…

  10. 12 CFR 303.41 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) A messenger service that is operated by a bank or its affiliate that picks up and delivers items relating to transactions in which deposits are received or checks paid or money lent. A messenger service... of this subpart. Banks contracting with third parties to provide messenger services should...

  11. 12 CFR 303.41 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) A messenger service that is operated by a bank or its affiliate that picks up and delivers items relating to transactions in which deposits are received or checks paid or money lent. A messenger service... of this subpart. Banks contracting with third parties to provide messenger services should...

  12. 12 CFR 303.41 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) A messenger service that is operated by a bank or its affiliate that picks up and delivers items relating to transactions in which deposits are received or checks paid or money lent. A messenger service... of this subpart. Banks contracting with third parties to provide messenger services should...

  13. Career Counseling for Women Preparing to Leave Abusive Relationships: A Social Cognitive Career Theory Approach

    ERIC Educational Resources Information Center

    Wachter Morris, Carrie A.; Shoffner, Marie F.; Newsome, Deborah W.

    2009-01-01

    Career counselors work with people from varied segments of society. For battered women, some of the challenges they face from intimate partner violence may significantly influence their career exploration and decision making. Social cognitive career theory (SCCT; R. W. Lent, S. D. Brown, & G. Hackett, 1994) is a framework that has important…

  14. Social Cognitive Predictors of Mexican American College Students' Academic and Life Satisfaction

    ERIC Educational Resources Information Center

    Ojeda, Lizette; Flores, Lisa Y.; Navarro, Rachel L.

    2011-01-01

    In this study, we used Lent's (2004) social cognitive model of well being to examine the academic and life satisfaction of 457 Mexican American college students attending a Hispanic-Serving Institution. Using structural equation modeling, results indicated that the model provided a good fit to the data. Specifically, we found positive relations…

  15. Applying Social Cognitive Career Theory to Predict Interests and Choice Goals in Statistics among Spanish Psychology Students

    ERIC Educational Resources Information Center

    Blanco, Angeles

    2011-01-01

    This study investigated the usefulness of social cognitive career theory--SCCT (Lent, Brown, and Hackett, 1994) in predicting interests and goals relating to statistics among psychology students. The participants were 1036 Spanish students who completed measurements of statistics-related mastery experiences, self-efficacy, outcome expectations,…

  16. 12 CFR 5.30 - Establishment, acquisition, and relocation of a branch.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... deposits are received, checks paid, or money lent. A branch does not include an automated teller machine... purposes of making deposits, paying checks, or borrowing money (e.g., an office established by the bank that receives deposits only through the mail); or (B) It is located at the site of, or is an extension...

  17. 12 CFR 5.30 - Establishment, acquisition, and relocation of a branch.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... deposits are received, checks paid, or money lent. A branch does not include an automated teller machine... purposes of making deposits, paying checks, or borrowing money (e.g., an office established by the bank that receives deposits only through the mail); or (B) It is located at the site of, or is an extension...

  18. 12 CFR 5.30 - Establishment, acquisition, and relocation of a branch.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... deposits are received, checks paid, or money lent. A branch does not include an automated teller machine... purposes of making deposits, paying checks, or borrowing money (e.g., an office established by the bank that receives deposits only through the mail); or (B) It is located at the site of, or is an extension...

  19. 12 CFR 5.30 - Establishment, acquisition, and relocation of a branch.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... deposits are received, checks paid, or money lent. A branch does not include an automated teller machine... purposes of making deposits, paying checks, or borrowing money (e.g., an office established by the bank that receives deposits only through the mail); or (B) It is located at the site of, or is an extension...

  20. The Social Cognitive Model of Job Satisfaction among Teachers: Testing and Validation

    ERIC Educational Resources Information Center

    Badri, Masood A.; Mohaidat, Jihad; Ferrandino, Vincent; El Mourad, Tarek

    2013-01-01

    The study empirically tests an integrative model of work satisfaction (0280, 0140, 0300 and 0255) in a sample of 5,022 teachers in Abu Dhabi in the United Arab Emirates. The study provided more support for the Lent and Brown (2006) model. Results revealed that this model was a strong fit for the data and accounted for 82% of the variance in work…

  1. Predicting the Job and Life Satisfaction of Italian Teachers: Test of a Social Cognitive Model

    ERIC Educational Resources Information Center

    Lent, Robert W.; Nota, Laura; Soresi, Salvatore; Ginevra, Maria C.; Duffy, Ryan D.; Brown, Steven D.

    2011-01-01

    This study tested a social cognitive model of work and life satisfaction (Lent & Brown, 2006, 2008) in a sample of 235 Italian school teachers. The model offered good overall fit to the data, though not all individual path coefficients were significant. Three of five predictors (favorable work conditions, efficacy-relevant supports, and…

  2. Precursors of Learning Experiences in Social Cognitive Career Theory

    ERIC Educational Resources Information Center

    Tokar, David M.; Thompson, Mindi N.; Plaufcan, Melissa R.; Williams, Christine M.

    2007-01-01

    This study extended the research on Social Cognitive Career Theory (SCCT; [Lent, R. W., Brown, S. D., & Hackett, G. (1994). Toward a unifying social cognitive theory of career and academic interest, choice, and performance. "Journal of Vocational Behavior," 45, 79-122]) by examining the contributions of 3 person inputs (personality, gender, and…

  3. A Longitudinal Examination of Adolescent Career Planning and Exploration Using a Social Cognitive Career Theory Framework

    ERIC Educational Resources Information Center

    Rogers, Mary E.; Creed, Peter A.

    2011-01-01

    This study used social cognitive career theory (Lent, Brown, & Hackett, 1994), as a framework to investigate predictors of career choice actions, operationalised as career planning and career exploration. The model was tested cross-sectionally and longitudinally with 631 high school students enrolled in Grades 10-12. Students completed measures of…

  4. Integrating Person and Situation Perspectives on Work Satisfaction: A Social-Cognitive View

    ERIC Educational Resources Information Center

    Lent, Robert W.; Brown, Steven D.

    2006-01-01

    Social cognitive career theory (Lent, Brown, & Hackett, 1994) was originally designed to help explain interest development, choice, and performance in career and educational domains. These three aspects of career/academic development were presented in distinct but overlapping segmental models. This article presents a fourth social cognitive model…

  5. Social Cognitive Career Theory, Conscientiousness, and Work Performance: A Meta-Analytic Path Analysis

    ERIC Educational Resources Information Center

    Brown, Steven D.; Lent, Robert W.; Telander, Kyle; Tramayne, Selena

    2011-01-01

    We performed a meta-analytic path analysis of an abbreviated version of social cognitive career theory's (SCCT) model of work performance (Lent, Brown, & Hackett, 1994). The model we tested included the central cognitive predictors of performance (ability, self-efficacy, performance goals), with the exception of outcome expectations. Results…

  6. Relation of Social-Cognitive Factors to Academic Satisfaction in Engineering Students

    ERIC Educational Resources Information Center

    Lent, Robert W.; Singley, Daniel; Sheu, Hung-Bin; Schmidt, Janet A.; Schmidt, Linda C.

    2007-01-01

    Lent (2004) posited a model of domain-specific and overall life satisfaction in which social-cognitive variables (self-efficacy, outcome expectations, environmental supports, and perceived goal progress) play key roles. In this study, the authors examined the relation of these variables to academic satisfaction. Participants were 153 engineering…

  7. Relationships between College Knowledge and College-Going Beliefs of Eighth Grade Students

    ERIC Educational Resources Information Center

    Wisely, Lynn Woodward

    2013-01-01

    This study examined the relationships of college knowledge and parent education level with these college-going beliefs: (a) self-efficacy, (b) outcome expectations, (c) likelihood both to go to and graduate from college, (d) choice intentions, and (e) educational goals. Social Cognitive Career Theory (Lent, Brown, & Hackett, 1994) provided the…

  8. Teaching Petrarchan and Anti-Petrarchan Discourses in Early Modern English Lyrics

    ERIC Educational Resources Information Center

    Ribes, Purificación

    2012-01-01

    The aim of the present article is to help students realize that Petrarchism has been an influential source of inspiration for Early Modern English lyrics. Its topics and conventions have lent themselves to a wide variety of appropriations which the present selection of texts for analysis tries to illustrate. A few telling examples from Spenser,…

  9. Pick a Pair. Pancake Pairs

    ERIC Educational Resources Information Center

    Miller, Pat

    2005-01-01

    Cold February weather and pancakes are a traditional pairing. Pancake Day began as a way to eat up the foods that were abstained from in Lent--traditionally meat, fat, eggs and dairy products. The best-known pancake event is The Pancake Day Race in Buckinghamshire, England, which has been run since 1445. This column describes pairs of books that…

  10. Fitting the Bill: Commissioned Theatre Projects on Human Rights in Pakistan--The Work of Karachi-Based Theatre Group "Tehrik e Niswan"

    ERIC Educational Resources Information Center

    Mundrawala, Asma

    2007-01-01

    Theatre practitioners in Pakistan's southern city Karachi have seen a recent surge of interest in the past two decades by donor agencies from the Western world to fund theatre companies and employ various forms of theatre for development to service their agendas and areas of interest within their target communities. This trend may have lent a…

  11. Chemical Machine Building on the Rise in China - USSR

    DTIC Science & Technology

    2007-11-02

    Republic, work has been carried out for the purpose of increasing the efficiency of a mechanical pyrite -roasting furnaces; this has resulted in a more...sulfuric acid production plants. In addition, research is being conducted on pyrite roasting in small-size turbu- lent burners. Larger diaphragm baths

  12. Influence of Social Cognitive and Ethnic Variables on Academic Goals of Underrepresented Students in Science and Engineering: A Multiple-Groups Analysis

    ERIC Educational Resources Information Center

    Byars-Winston, Angela; Estrada, Yannine; Howard, Christina; Davis, Dalelia; Zalapa, Juan

    2010-01-01

    In this study we investigated the academic interests and goals of 223 African American, Latino/a, Southeast Asian, and Native American undergraduate students in 2 groups: biological science (BIO) and engineering (ENG) majors. Using social cognitive career theory (Lent, Brown, & Hackett, 1994), we examined the relationships of social cognitive…

  13. Learning To "See Beyond": Sixth-Grade Students' Artistic Perceptions of "The Giver."

    ERIC Educational Resources Information Center

    Whitelaw, Jessica; Wolf, Shelby A.

    2001-01-01

    Encourages students to slow down and to reflect upon what they had read. Focuses on the visual arts, particularly for their capacity to help move students from the concrete to the abstract. Notes that Lowry's (1993) novel "The Giver" particularly lent itself to this approach because its powerful visual imagery encourages readers to return to and…

  14. Two Tests of the Social Cognitive Model of Well-Being in Portuguese College Students

    ERIC Educational Resources Information Center

    Lent, Robert W.; Taveira, Maria do Ceu; Lobo, Cristina

    2012-01-01

    A social cognitive model of well-being (Lent & Brown, 2006, 2008) was tested in two studies (one cross-sectional, one longitudinal) with Portuguese college students. Participants in Study 1 (N = 366) completed measures of academic self-efficacy, environmental support, goal progress, academic satisfaction and stress, trait positive affect, and…

  15. 12 CFR 712.4 - What must an FCU and a CUSO do to maintain separate corporate identities?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... borrowings by the CUSO indicate that the FCU is not liable. (b) Legal opinion. Prior to an FCU investing in a... will limit potential exposure of the FCU to no more than the loss of funds invested in, or lent to, the... a manner that will limit potential exposure of the FCU to no more than the loss of funds invested in...

  16. College-Level Choice of Latino High School Students: A Social-Cognitive Approach

    ERIC Educational Resources Information Center

    Gonzalez, Laura M.

    2012-01-01

    Latino students attend 2-year colleges more often than 4-year colleges. This has an impact on the rate of bachelor's degree attainment, because the transfer rate between the 2 levels is low. The author uses national data to identify predictors associated with college-level choice and then uses social-cognitive career theory (Lent, Brown, &…

  17. Lithospheric Profiles in the Southwestern U. S. using Nevada Test Site Sources

    DTIC Science & Technology

    1993-07-31

    of mountain ranges on seismic waves is a major concern in efforts to monitor seismic events in many areas around the world . This effort represents...for gabbros at upper crustal pressures. Gabbro , the intrusive equiva- lent of basalt, has P-wave velocities of 6.83 km/fcc near the surface to about

  18. Perceived Social Status and Learning Experiences in Social Cognitive Career Theory

    ERIC Educational Resources Information Center

    Thompson, Mindi N.; Dahling, Jason J.

    2012-01-01

    The purpose of this study was to test a model based on Social Cognitive Career Theory (Lent, Brown, & Hackett, 1994) that placed perceived social status as an antecedent of career-related learning experiences, self-efficacy, and outcome expectations. Gender was included in the present model and results indicated that gender related as expected to…

  19. The Moral Impotence of Contemporary Experts

    ERIC Educational Resources Information Center

    Filion, Yves R.

    2004-01-01

    Technological growth in developed and developing countries in the 20th century has lent a great deal of importance to scientific reasoning in the management of human affairs. An important outgrowth has been the development of systems thinking to organize the workplace. The business reengineering process and the enterprise resource planning system…

  20. Initial Scale Development of the Contextual Support for Post-Secondary Planning Scales

    ERIC Educational Resources Information Center

    Ali, Saba Rasheed; Martens, Jessica Kelly; Button, Christopher; Larma, Nicholas C.

    2011-01-01

    Vocational psychologists and career theorists have articulated the importance of social support in the development of career plans for high school youth. More recently, Lent, Brown, and Hackett carefully articulated the location of contextual supports in the Social Cognitive Career Theory (SCCT) framework. However, there is a paucity of research…

  1. Predicting the Job and Life Satisfaction of Italian Teachers: Test of a Social Cognitive Model

    ERIC Educational Resources Information Center

    Lent, Robert W.; Nota, Laura; Soresi, Salvatore; Ginevra, Maria C.; Duffy, Ryan D.; Brown, Steven D.

    2011-01-01

    This study tested a social cognitive model of work and life satisfaction (Lent & Brown, 2006, 2008) in a sample of 235 Italian school teachers. The model offered good overall fit to the data, though not all individual path coefficients were significant. Three of five predictors (favorable work conditions, efficacy-relevant supports, and…

  2. Comparative measurements of stratospheric particulate content by aircraft and ground-based lidar. [aerosol sampling and scattering data analysis

    NASA Technical Reports Server (NTRS)

    Viezee, W.; Russell, P. B.; Hake, R. D., Jr.

    1974-01-01

    The matching method of lidar data analysis is explained, and the results from two flights studying the stratospheric aerosol using lidar techniques are summarized and interpreted. Support is lent to the matching method of lidar data analysis by the results, but it is not yet apparent that the analysis technique leads to acceptable results on all nights in all seasons.

  3. A Longitudinal Examination of the Social-Cognitive Model Applied to High School Girls' Choices of Nontraditional College Majors and Aspirations

    ERIC Educational Resources Information Center

    Nauta, Margaret M.; Epperson, Douglas L.

    2003-01-01

    This study tested a partial version of R. W. Lent, S. D. Brown, and G. Hackett's (1994) social-cognitive career theory model. Among 204 high school girls who attended science, math, and engineering (SME) career conferences, the authors used a 4-year longitudinal design to predict the choice of an SME college major and SME self-efficacy and outcome…

  4. Freshman Engineering Students At-Risk of Non-Matriculation: Self-Efficacy for Academic Learning

    ERIC Educational Resources Information Center

    Ernst, Jeremy V.; Bowen, Bradley D.; Williams, Thomas O.

    2016-01-01

    Students identified as at-risk of non-academic continuation have a propensity toward lower academic self-efficacy than their peers (Lent, 2005). Within engineering, self-efficacy and confidence are major markers of university continuation and success (Lourens, 2014 Raelin, et al., 2014). This study explored academic learning self-efficacy specific…

  5. Game-Based Learning: How to Delight and Instruct in The 21st Century

    ERIC Educational Resources Information Center

    Foreman, Joel

    2004-01-01

    Not long after he completed his Ph.D. at the University of Michigan, Mike Van Lent used his interest in videogames and artificial intelligence to land a research professorship at the University of Southern California (USC). There he edits the Journal of Game Development and conducts studies for the Institute for Creative Technologies, a $45…

  6. Social-Cognitive Factors Affecting Clients' Career and Life Satisfaction after Counseling

    ERIC Educational Resources Information Center

    Verbruggen, Marijke; Sels, Luc

    2010-01-01

    This study examines factors affecting clients' career and life satisfaction in the first 6 months after having participated in career counseling. In particular, we tested a large subset of the recent social-cognitive model of work satisfaction of Lent and Brown using a longitudinal data set of 195 former counseling clients. Our results showed that…

  7. Legal Forum: The Changing Federal Role in Bilingual Education.

    ERIC Educational Resources Information Center

    McCarthy, Martha M.

    1986-01-01

    Presents a brief overview of historical developments and recent activity regarding the federal government's policy toward bilingual education. Focuses mainly on the Supreme Court's Lau v. Vichols decision of 1974, which lent support to bilingual education, and the Reagan Administration's challenges to current funding practices for such education.…

  8. Utilizing Cognitive Dissonance Theory To Improve Student Ratings of College Faculty Members.

    ERIC Educational Resources Information Center

    Carson, Rebecca Davis; Smith, Albert B.; Olivarez, Arturo, Jr.

    This study examined the impact of mid-semester student ratings feedback on a faculty's end-of-semester student ratings. The positive direction of the end-of-semester ratings in the two mid-semester feedback groups lent support to the premise that cognitive dissonance theory and various forms of mid-semester, student rating feedback can be used to…

  9. Adolescents on the Edge: Stories and Lessons to Transform Learning

    ERIC Educational Resources Information Center

    Lent, ReLeah Cossett; Baca, Jimmy Santiago

    2010-01-01

    Fusing Jimmy Santiago Baca's talents as a writer of memoir with ReLeah Cossett Lent's expertise in building and empowering classroom communities, this book offers a completely new approach to reaching at-risk adolescents. Centered around conflicts and life-altering choices, Baca's gripping personal narratives--delivered through short stories and…

  10. Adolescents on the Edge: Stories and Lessons to Transform Learning

    ERIC Educational Resources Information Center

    Lent, ReLeah Cossett; Baca, Jimmy Santiago

    2010-01-01

    Fusing Jimmy Santiago Baca's talents as a writer of memoir with ReLeah Cossett Lent's expertise in building and empowering classroom communities, this book offers a completely new approach to reaching at-risk adolescents. Centered around conflicts and life-altering choices, Baca's gripping personal narratives--delivered through short stories and…

  11. Career Goals, Preferences, and Support for Students in Psychology

    ERIC Educational Resources Information Center

    Miles, Belva A.

    2013-01-01

    Bandura's (1986) social cognitive theory has been adapted by Lent, Brown, and Hackett (1994) to form social cognitive career theory (SCCT). The theory posits three interlocking steps in academic and career development: interest, choice goal, and choice goal action. Self-efficacy, outcome expectations, barriers, and supports are hypothesized to…

  12. Longitudinal Relations of Self-Efficacy to Outcome Expectations, Interests, and Major Choice Goals in Engineering Students

    ERIC Educational Resources Information Center

    Lent, Robert W.; Sheu, Hung-Bin; Singley, Daniel; Schmidt, Janet A.; Schmidt, Linda C.; Gloster, Clay S.

    2008-01-01

    We examined the nature of the temporal relations among the core person variables in the social cognitive model of academic and career choice [Lent, R. W., Brown, S. D., & Hackett, G. (1994). Toward a unifying social cognitive theory of career and academic interest, choice, and performance [Monograph]. "Journal of Vocational Behavior," 45,…

  13. Testing the Choice Model of Social Cognitive Career Theory across Holland Themes: A Meta-Analytic Path Analysis

    ERIC Educational Resources Information Center

    Sheu, Hung-Bin; Lent, Robert W.; Brown, Steven D.; Miller, Matthew J.; Hennessy, Kelly D.; Duffy, Ryan D.

    2010-01-01

    Social cognitive career theory (SCCT; Lent, Brown, & Hackett, 1994) seeks to explain the factors that shape educational and vocational interests and choices. We used meta-analytic path analyses to synthesize data (from 1981 to 2008) relevant to SCCT's interest and choice hypotheses, organizing the literature according to Holland's (1997) broad…

  14. Influence of Social Cognitive and Ethnic Variables on Academic Goals of Underrepresented Students in Science and Engineering: A Multiple-Groups Analysis

    ERIC Educational Resources Information Center

    Byars-Winston, Angela; Estrada, Yannine; Howard, Christina; Davis, Dalelia; Zalapa, Juan

    2010-01-01

    In this study we investigated the academic interests and goals of 223 African American, Latino/a, Southeast Asian, and Native American undergraduate students in 2 groups: biological science (BIO) and engineering (ENG) majors. Using social cognitive career theory (Lent, Brown, & Hackett, 1994), we examined the relationships of social cognitive…

  15. Integrating Person and Situation Perspectives on Work Satisfaction: A Social-Cognitive View

    ERIC Educational Resources Information Center

    Lent, Robert W.; Brown, Steven D.

    2006-01-01

    Social cognitive career theory (Lent, Brown, & Hackett, 1994) was originally designed to help explain interest development, choice, and performance in career and educational domains. These three aspects of career/academic development were presented in distinct but overlapping segmental models. This article presents a fourth social cognitive model…

  16. Social Cognitive Career Theory, Conscientiousness, and Work Performance: A Meta-Analytic Path Analysis

    ERIC Educational Resources Information Center

    Brown, Steven D.; Lent, Robert W.; Telander, Kyle; Tramayne, Selena

    2011-01-01

    We performed a meta-analytic path analysis of an abbreviated version of social cognitive career theory's (SCCT) model of work performance (Lent, Brown, & Hackett, 1994). The model we tested included the central cognitive predictors of performance (ability, self-efficacy, performance goals), with the exception of outcome expectations. Results…

  17. Career Goals, Preferences, and Support for Students in Psychology

    ERIC Educational Resources Information Center

    Miles, Belva A.

    2013-01-01

    Bandura's (1986) social cognitive theory has been adapted by Lent, Brown, and Hackett (1994) to form social cognitive career theory (SCCT). The theory posits three interlocking steps in academic and career development: interest, choice goal, and choice goal action. Self-efficacy, outcome expectations, barriers, and supports are hypothesized to…

  18. Schooling along the Color Line: Progressives and the Education of Blacks in the New South.

    ERIC Educational Resources Information Center

    Dennis, Michael J.

    1998-01-01

    Examines the writings and speeches of several "progressive" southern academics who formed the basis of the crusade for industrial education for blacks. Shows how these intellectuals lent the authority of their institutions and the weight of their ideas to promote an educational system designed to maintain racial control and black…

  19. Survival and growth of thirteen tree species in coastal Oregon.

    Treesearch

    James T. Krygier

    1958-01-01

    Extraordinary growth of introduced tree species—such as Monterey and other pines in Australia, New Zealand, and South Africa, and Sitka spruce, Douglas-fir, and grand fir in Great Britain—has lent impetus to tests of exotic species. Planting of most exotics in the United States has generally met with poor success. Yet there is always speculation that...

  20. School Discipline Disparity: Converging Efforts for Better Student Outcomes

    ERIC Educational Resources Information Center

    Okilwa, Nathern S.; Robert, Catherine

    2017-01-01

    School policies and practices have historically lent themselves to disproportionate suspension and expulsion rates based on students' race, gender, and disability. The disparity between racial minorities, particularly Black males, and their White peers has generated concern from various stakeholders. Using Kingdon's ("Agendas, alternatives,…

  1. Precursors of Learning Experiences in Social Cognitive Career Theory

    ERIC Educational Resources Information Center

    Tokar, David M.; Thompson, Mindi N.; Plaufcan, Melissa R.; Williams, Christine M.

    2007-01-01

    This study extended the research on Social Cognitive Career Theory (SCCT; [Lent, R. W., Brown, S. D., & Hackett, G. (1994). Toward a unifying social cognitive theory of career and academic interest, choice, and performance. "Journal of Vocational Behavior," 45, 79-122]) by examining the contributions of 3 person inputs (personality, gender, and…

  2. Fitting the Bill: Commissioned Theatre Projects on Human Rights in Pakistan--The Work of Karachi-Based Theatre Group "Tehrik e Niswan"

    ERIC Educational Resources Information Center

    Mundrawala, Asma

    2007-01-01

    Theatre practitioners in Pakistan's southern city Karachi have seen a recent surge of interest in the past two decades by donor agencies from the Western world to fund theatre companies and employ various forms of theatre for development to service their agendas and areas of interest within their target communities. This trend may have lent a…

  3. The Moral Impotence of Contemporary Experts

    ERIC Educational Resources Information Center

    Filion, Yves R.

    2004-01-01

    Technological growth in developed and developing countries in the 20th century has lent a great deal of importance to scientific reasoning in the management of human affairs. An important outgrowth has been the development of systems thinking to organize the workplace. The business reengineering process and the enterprise resource planning system…

  4. Effects of Social Supports on the Career Choice Consideration of Chinese Farmers: A Social Cognitive Perspective

    ERIC Educational Resources Information Center

    Zhao, Li

    2012-01-01

    Drawing from social cognitive career theory (Lent, Brown, & Hackett, 1994), this study explored social supports' influence on the career choice consideration of farmers during China's current process of urbanization. A questionnaire was designed based on interviews with 140 people and a pretest with a sample of 419 participants. A total of 628…

  5. Pelvic radiation disease management by hyperbaric oxygen therapy: prospective study of 44 patients.

    PubMed

    Ouaïssi, Mehdi; Tran, Stephanie; Mege, Diane; Latrasse, Vivien; Barthelemy, Alain; Pirro, Nicolas; Grandval, Philippe; Lassey, James; Sielezneff, Igor; Sastre, Bernard; Coulange, Mathieu

    2014-01-01

    Pelvic radiation disease (PRD) occurs in 2-11% of patients undergoing pelvic radiation for urologic and gynecologic malignancies. Hyperbaric oxygen therapy (HBOT) has previously been described as a noninvasive therapeutic option for the treatment of PRD. the purpose of study was to analyze prospectively the results of HBOT in 44 consecutive patients with PRD who were resistant to conventional oral or topical treatments. Material and Methods. The median age of the cohort was 65.7 years (39-85). Twenty-seven percent of patients required blood transfusion (n = 12). The median of delay between radiotherapy and HBOT was 26 months (3-175). We evaluated the results of HBOT, using SOMA-LENT Scale. Results. SOMA-LENT score was decreased in 59% of patient. The median of SOMA-LENT score before HBOT was significantly higher, being equal to 14 (0-36), than after HBOT with the SOMA-LENT score of 12 (0-38) (P = 0.003). Tenesmus (P = 0.02), bleeding (P = 0.0001), and ulceration (P = 0.001) significantly decreased after HBOT. Regarding patients with colostomy, 33% (n = 4) benefited from colostomies closure. HBOT was generally well tolerated. Only one patient stopped precociously due to transient myopia. Conclusion. This study is in favor of the interest of HBOT in pelvic radiation disease treatment (PRD).

  6. Student Teachers' Perceptions of Cooperating Teachers as Teacher Educators: Development of Standards Based Scales

    ERIC Educational Resources Information Center

    Holbert, Romena M. Garrett

    2011-01-01

    Cooperating teachers play important roles in student teachers' development as educators. The purpose of this study was to develop a measure that enables systematic investigation of the actions and interactions of cooperating teachers during student teaching. Three sets of educational standards lent focus to this work. The measures developed were…

  7. Mexican American High Schools' Post-Secondary Educational Goals: Applying Social Cognitive Career Theory

    ERIC Educational Resources Information Center

    Flores, Lisa Y.; Navarro, Rachel L.; DeWitz, Joseph

    2008-01-01

    A multivariate multiple regression analysis predicting the educational goal aspirations and expectations of 89 Mexican American high school students was examined based on Lent, Brown, and Hackett's (1994) Social Cognitive Career Theory and prior research findings with Mexican American samples. No gender or generational status differences were…

  8. Social Cognitive and Cultural Orientation Predictors of Well-Being in Asian American College Students

    ERIC Educational Resources Information Center

    Hui, Kayi; Lent, Robert W.; Miller, Matthew J.

    2013-01-01

    This study examined the predictive utility of Lent and Brown's social cognitive model of educational and work well-being with a sample of Asian American college students, indexing well-being in terms of academic and social domain satisfaction. In addition, we examined the role of acculturation and enculturation as culture-specific predictors of…

  9. Role of Family Background, Student Behaviors, and School-Related Beliefs in Predicting High School Dropout

    ERIC Educational Resources Information Center

    Parr, Alyssa K.; Bonitz, Verena S.

    2015-01-01

    The authors' purpose was to test a parsimonious model derived from social cognitive career theory (R. W. Lent, S. D. Brown, & G. Hackett, 1994) and expectancy value theory (J. S. Eccles & A. Wigfield, 2002) that integrates groups of variables (demographic background, student behaviors, and school-related beliefs) with the goal of…

  10. The Role of Career Barriers in High School Students' Career Choice Behavior in Taiwan

    ERIC Educational Resources Information Center

    Tien, Hsiu-Lan Shelley; Wang, Ying-Fen; Liu, Ling-Chun

    2009-01-01

    The purpose of this study was to examine the role of career barriers in social cognitive career theory (R. W. Lent, S. D. Brown, & G. Hackett, 1994). The participants were 584 high school students in Taiwan, Republic of China. The gender differences in perceived career barriers and career self-efficacy were significant. Results of hierarchical…

  11. Testing a Model of Nontraditional Career Choice Goals with Mexican American Adolescent Men

    ERIC Educational Resources Information Center

    Flores, Lisa Y.; Navarro, Rachel L.; Smith, Jamie L.; Ploszaj, Ann M.

    2006-01-01

    This study examined the nontraditional career choice goals of 302 Mexican American adolescent men using an extended version of Lent, Brown, and Hacketts (1994) career choice model. It was hypothesized that several background contextual variables (e.g., acculturation level, parental support, perceived occupational gender barriers) would predict…

  12. Two Tests of the Social Cognitive Model of Well-Being in Portuguese College Students

    ERIC Educational Resources Information Center

    Lent, Robert W.; Taveira, Maria do Ceu; Lobo, Cristina

    2012-01-01

    A social cognitive model of well-being (Lent & Brown, 2006, 2008) was tested in two studies (one cross-sectional, one longitudinal) with Portuguese college students. Participants in Study 1 (N = 366) completed measures of academic self-efficacy, environmental support, goal progress, academic satisfaction and stress, trait positive affect, and…

  13. College-Level Choice of Latino High School Students: A Social-Cognitive Approach

    ERIC Educational Resources Information Center

    Gonzalez, Laura M.

    2012-01-01

    Latino students attend 2-year colleges more often than 4-year colleges. This has an impact on the rate of bachelor's degree attainment, because the transfer rate between the 2 levels is low. The author uses national data to identify predictors associated with college-level choice and then uses social-cognitive career theory (Lent, Brown, &…

  14. (S,S) Policies for a Dynamic Inventory Model with Stochastic Lead Times.

    DTIC Science & Technology

    1980-12-01

    University of North Carolina at Chapel Hill, 109 pp. Schultz, C. R., R. Ehrhardt, and A. MacCormick (1977), Forecastin g Opew atin Characteristics of (sS...colleagues, Professors Alastair MacCormick and Harvey M. Wagner. He also expresses his appreciation to James Lent who per- formed the computer calculations

  15. A Model of Client Impression Formation.

    ERIC Educational Resources Information Center

    Bodden, Jack L.; Winer, Jane L.

    1978-01-01

    The model describes the clients' impression-formation process, describes changes in client impressions as therapy progresses, and suggests the relevance of client impressions for therapy outcome. An attempt at empirical validation by using a clinical population lent some support to certain aspects of the proposed model. (Author)

  16. Career Counseling as an Environmental Support: Exploring Influences on Career Choice, Career Decision-Making Self-Efficacy, and Career Barriers

    ERIC Educational Resources Information Center

    Makela, Julia Panke

    2011-01-01

    This study was motivated by concerns regarding the difficult academic and career choices facing today's college students as they navigate higher education and encounter career barriers along their paths. Using Social Cognitive Career Theory (SCCT; Lent, Brown, & Hackett, 1994) as a primary framework, the study sought to understand the role that…

  17. Gender in the Development of Career Related Learning Experiences

    ERIC Educational Resources Information Center

    Williams, Christine Marie

    2010-01-01

    Social Cognitive Career Theory (SCCT; Lent, Brown, & Hackett, 1994) delineates the ways in which social forces may influence women's career development and create gender segregation in different types of occupations (see Betz, 2007 for a review). However, a number of questions remain, specifically in regards to how social forces may shape the core…

  18. Where Are the Women in Women's Sports? Predictors of Female Athletes' Interest in a Coaching Career

    ERIC Educational Resources Information Center

    Moran-Miller, Kelli; Flores, Lisa Y.

    2011-01-01

    In this study, we used social cognitive career theory (Lent, Brown, & Hackett, 1994) to examine the development of female athletes' career interest in coaching and, specifically, the impact of contextual factors (female coaching role models, working hours, and perceived discrimination) on coaching self-efficacy and outcome expectations.…

  19. Modeling College Women's Perceptions of Elite Leadership Positions with Social Cognitive Career Theory

    ERIC Educational Resources Information Center

    Yeagley, Emily E.; Subich, Linda M.; Tokar, David M.

    2010-01-01

    The utility of Social Cognitive Career Theory (SCCT; Lent, Brown, & Hackett, 1994) for predicting college women's interests and goals for positions of elite leadership was examined with 156 undergraduate women at a public university. They completed measures of elite leadership self-efficacy expectations, outcome expectations, interests, and goals.…

  20. The Gendered Nature of Career Related Learning Experiences: A Social Cognitive Career Theory Perspective

    ERIC Educational Resources Information Center

    Williams, Christine M.; Subich, Linda M.

    2006-01-01

    The learning experiences questionnaire (LEQ; Schaub & Tokar, 2005) was used to examine learning experiences as they relate to SCCT (Lent, Brown, & Hackett, 1994) across the Holland (1997) RIASEC typology. In particular, differences in men's and women's career related learning experiences were examined. A sample of 319 undergraduates at a public…

  1. Testing the Choice Model of Social Cognitive Career Theory across Holland Themes: A Meta-Analytic Path Analysis

    ERIC Educational Resources Information Center

    Sheu, Hung-Bin; Lent, Robert W.; Brown, Steven D.; Miller, Matthew J.; Hennessy, Kelly D.; Duffy, Ryan D.

    2010-01-01

    Social cognitive career theory (SCCT; Lent, Brown, & Hackett, 1994) seeks to explain the factors that shape educational and vocational interests and choices. We used meta-analytic path analyses to synthesize data (from 1981 to 2008) relevant to SCCT's interest and choice hypotheses, organizing the literature according to Holland's (1997) broad…

  2. Math and Science Social Cognitive Variables in College Students: Contributions of Contextual Factors in Predicting Goals

    ERIC Educational Resources Information Center

    Byars-Winston, Angela M.; Fouad, Nadya A.

    2008-01-01

    This study investigated the influence of two contextual factors, parental involvement and perceived career barriers, on math/science goals. Using social cognitive career theory (SCCT; Lent, Brown, & Hackett, 1994), a path model was tested to investigate hypothesized relationships between math- and science-related efficacy beliefs (i.e., task and…

  3. Pick a Pair. Pancake Pairs

    ERIC Educational Resources Information Center

    Miller, Pat

    2005-01-01

    Cold February weather and pancakes are a traditional pairing. Pancake Day began as a way to eat up the foods that were abstained from in Lent--traditionally meat, fat, eggs and dairy products. The best-known pancake event is The Pancake Day Race in Buckinghamshire, England, which has been run since 1445. This column describes pairs of books that…

  4. Where Are the Women in Women's Sports? Predictors of Female Athletes' Interest in a Coaching Career

    ERIC Educational Resources Information Center

    Moran-Miller, Kelli; Flores, Lisa Y.

    2011-01-01

    In this study, we used social cognitive career theory (Lent, Brown, & Hackett, 1994) to examine the development of female athletes' career interest in coaching and, specifically, the impact of contextual factors (female coaching role models, working hours, and perceived discrimination) on coaching self-efficacy and outcome expectations.…

  5. Comparative measurements of stratospheric particulate content by aircraft and ground-based lidar. [aerosol sampling and scattering data analysis

    NASA Technical Reports Server (NTRS)

    Viezee, W.; Russell, P. B.; Hake, R. D., Jr.

    1974-01-01

    The matching method of lidar data analysis is explained, and the results from two flights studying the stratospheric aerosol using lidar techniques are summarized and interpreted. Support is lent to the matching method of lidar data analysis by the results, but it is not yet apparent that the analysis technique leads to acceptable results on all nights in all seasons.

  6. Math Interest and Choice Intentions of Non-Traditional African-American College Students

    ERIC Educational Resources Information Center

    Waller, Byron

    2006-01-01

    This study investigated the application of the social-cognitive career theory (SCCT) (Lent, Brown, & Hackett, 1994) to the math interest and choice intentions of non-traditional African-American college student population. The associations between the social-cognitive constructs were examined to identify their relation to math interest and choice…

  7. Feeling the Threat: Stereotype Threat as a Contextual Barrier to Women's Science Career Choice Intentions

    ERIC Educational Resources Information Center

    Deemer, Eric D.; Thoman, Dustin B.; Chase, Justin P.; Smith, Jessi L.

    2014-01-01

    Social cognitive career theory (SCCT; Lent, Brown, & Hackett, 1994, 2000) holds that contextual barriers inhibit self-efficacy and goal choice intentions from points both near and far from the active career development situation. The current study examined the influence of one such proximal barrier, stereotype threat, on attainment of these…

  8. Desirability of Personality Dimensions: Auto- and Heteroperceptions by American and German College Students

    ERIC Educational Resources Information Center

    Crott, Helmut W.; Baltes, Paul B.

    1973-01-01

    The results of this study seem to support the usefulness of desirability judgments and personality items as vehicles for intercultural research. Findings lent support to the suggestion that the German student population has been subjected to marked cultural or generational change with regard to evaluative aspects of core personality dimensions.…

  9. Predicting the Math/Science Career Goals of Low-Income Prospective First-Generation College Students

    ERIC Educational Resources Information Center

    Garriott, Patton O.; Flores, Lisa Y.; Martens, Matthew P.

    2013-01-01

    The present study used social cognitive career theory (SCCT; Lent, Brown, & Hackett, 1994) to predict the math/science goal intentions of a sample of low-income prospective first-generation college students (N = 305). Structural equation modeling was used to test a model depicting relationships between contextual (i.e., social class, learning…

  10. Nanostructured Ceramics Obtained Under Extreme Conditions of Pressure and Temperature

    DTIC Science & Technology

    2011-11-20

    Alessandro Bof Oliveira, Patrícia Rodrigues da Silva, Pâmela Andréa Mantey Dos Santos, Tania Maria Haas Costa, Marcia Russman Gallas. An Approach for...Portuguese), 32:1926-1933, 2009. 15. Mesquita, Alexandra ; Bernardi , Maria Inês B. ; Mastelaro, Valmor R. ; Lente, Manuel H. ; Eiras, José A

  11. Examining a Model of Life Satisfaction among Unemployed Adults

    ERIC Educational Resources Information Center

    Duffy, Ryan D.; Bott, Elizabeth M.; Allan, Blake A.; Torrey, Carrie L.

    2013-01-01

    The present study examined a model of life satisfaction among a diverse sample of 184 adults who had been unemployed for an average of 10.60 months. Using the Lent (2004) model of life satisfaction as a framework, a model was tested with 5 hypothesized predictor variables: optimism, job search self-efficacy, job search support, job search…

  12. A Longitudinal Examination of Adolescent Career Planning and Exploration Using a Social Cognitive Career Theory Framework

    ERIC Educational Resources Information Center

    Rogers, Mary E.; Creed, Peter A.

    2011-01-01

    This study used social cognitive career theory (Lent, Brown, & Hackett, 1994), as a framework to investigate predictors of career choice actions, operationalised as career planning and career exploration. The model was tested cross-sectionally and longitudinally with 631 high school students enrolled in Grades 10-12. Students completed measures of…

  13. Game-Based Learning: How to Delight and Instruct in The 21st Century

    ERIC Educational Resources Information Center

    Foreman, Joel

    2004-01-01

    Not long after he completed his Ph.D. at the University of Michigan, Mike Van Lent used his interest in videogames and artificial intelligence to land a research professorship at the University of Southern California (USC). There he edits the Journal of Game Development and conducts studies for the Institute for Creative Technologies, a $45…

  14. The Revenue Imperative: Finding New Funding Streams in the Face of Budget Cuts

    ERIC Educational Resources Information Center

    Fernandez, Kim

    2011-01-01

    By all accounts, 2010 was a watershed year for community colleges. President Obama touted the role these institutions play in putting Americans back to work, and widespread enrollment increases lent credibility to the notion that students at long last are realizing the benefits of two-year quality and value compared with the higher price of…

  15. Relation of Social-Cognitive Factors to Academic Satisfaction in Engineering Students

    ERIC Educational Resources Information Center

    Lent, Robert W.; Singley, Daniel; Sheu, Hung-Bin; Schmidt, Janet A.; Schmidt, Linda C.

    2007-01-01

    Lent (2004) posited a model of domain-specific and overall life satisfaction in which social-cognitive variables (self-efficacy, outcome expectations, environmental supports, and perceived goal progress) play key roles. In this study, the authors examined the relation of these variables to academic satisfaction. Participants were 153 engineering…

  16. Facing the Issues: Challenges, Censorship, and Reflection through Dialogue

    ERIC Educational Resources Information Center

    Lent, ReLeah Cossett

    2008-01-01

    ReLeah Cossett Lent provides practical advice for ensuring that books are kept on shelves and in classrooms for students to read. She outlines steps for creating professional learning communities that engage with censorship issues and prepare schools to deal with book challenges in thoughtful, supportive ways. (Contains 4 figures.)

  17. In the Company of Critical Thinkers

    ERIC Educational Resources Information Center

    Lent, ReLeah

    2006-01-01

    What if we could truly engage high schools students in learning by actively involving them in research and discussion leading to concrete actions on issues that interest them? Lent describes her experiences working with student study groups composed of high school students and teachers or adult community members. Study groups differ from…

  18. Curvature Effects on the Heat Transfer Performance of Three-Dimensional Film Cooling of Gas Turbine Blades.

    DTIC Science & Technology

    1982-08-01

    Hill. 9 tiolteinot.H.J., Fockert. F. R.(;.. Erick -ien. V. .and Ramsey.J.. W.. New ’t’,rk. 191368. pp. 192-211, pp. 470. Journal of Engineering for Power...conven- been reported by Erikson and Goldstein [91 and lent means of analyzing the problem has been to con- Jabbari and Goldstein [101. In these

  19. 45 CFR 1160.5 - Eligibility for domestic exhibitions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... while on Exhibition in the United States. (a)(1) Example 1. An American museum is undergoing renovation... go on tour to three other museums in the United States. Many of these works have never been lent for travel, and this will be a unique and the last opportunity for museum visitors in other parts of...

  20. 45 CFR 1160.5 - Eligibility for domestic exhibitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... while on Exhibition in the United States. (a)(1) Example 1. An American museum is undergoing renovation... go on tour to three other museums in the United States. Many of these works have never been lent for travel, and this will be a unique and the last opportunity for museum visitors in other parts of...

  1. 45 CFR 1160.5 - Eligibility for domestic exhibitions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... while on Exhibition in the United States. (a)(1) Example 1. An American museum is undergoing renovation... go on tour to three other museums in the United States. Many of these works have never been lent for travel, and this will be a unique and the last opportunity for museum visitors in other parts of...

  2. 12 CFR 208.110 - Sale of bank's money orders off premises as establishment of branch office.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... deposits are received, or checks paid, or money lent.” The basic question is whether the sale of a bank's... 12 Banks and Banking 2 2011-01-01 2011-01-01 false Sale of bank's money orders off premises as establishment of branch office. 208.110 Section 208.110 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF...

  3. An Alternative U.S. Military Strategy for Africa in a Post-Cold War World

    DTIC Science & Technology

    2007-11-02

    provided equipment. A Belgian officer lent invaluable assistance in planning a clinic for Ruanda . In Malawi, the British help train Malawi engineers.whom...allies. For example, contacts established by HQ USEUCOM with the West German Ministry of Defense led to cooperation in projects in Ruanda and Niger

  4. Study of Nonlinear Mesoscale Processes: Applications to Lagrangian Data Analysis and Subgrid Scale Parameterization

    DTIC Science & Technology

    1997-09-30

    regions, and assimilation methods . In general, the accuracy of both short-term and long-term predictions improves signif- icantly with the assimilation of...Foundation (TAO Project). Assimilation methods for nonlinear Lagrangian processes and parameterization of turbu- lent phenomena using stochastic models are

  5. Attending to Place, Race, and Community: Trans-Local Partnering between Scholars and Activists in Central Appalachia and the Black Belt South

    ERIC Educational Resources Information Center

    Harris, Rosalind; Bernard, Marcus; Mullinax, Maureen; Worthen, Dreamal; Finch, Sokoya; Womack, Veronica

    2012-01-01

    The communities in the Black Belt South and Central Appalachian regions in the United States share long histories of persistent subjugation. Both regions also have strong traditions of partnerships between grassroots activists and scholars--partnerships that have, at times, lent resilient responses to political, economic and cultural challenges,…

  6. Variables that Affect Math Teacher Candidates' Intentions to Integrate Computer-Assisted Mathematics Education (CAME)

    ERIC Educational Resources Information Center

    Erdogan, Ahmet

    2010-01-01

    Based on Social Cognitive Carier Theory (SCCT) (Lent, Brown, & Hackett, 1994, 2002), this study tested the effects of mathematics teacher candidates' self-efficacy in, outcome expectations from, and interest in CAME on their intentions to integrate Computer-Assisted Mathematics Education (CAME). While mathematics teacher candidates' outcome…

  7. The Development and Initial Validation of Social Cognitive Career Theory Instruments to Measure Choice of Medical Specialty and Practice Location

    ERIC Educational Resources Information Center

    Rogers, Mary E.; Creed, Peter A.; Searle, Judy

    2009-01-01

    Social cognitive career theory served as the basis for the instrument development for scales assessing self-efficacy, outcome expectations, and goals to predict medical career choice. Lent and Brown's conceptualization of social cognitive constructs guided the development of items to measure choice of medical specialty and practice location. Study…

  8. Social-Cognitive Factors Affecting Clients' Career and Life Satisfaction after Counseling

    ERIC Educational Resources Information Center

    Verbruggen, Marijke; Sels, Luc

    2010-01-01

    This study examines factors affecting clients' career and life satisfaction in the first 6 months after having participated in career counseling. In particular, we tested a large subset of the recent social-cognitive model of work satisfaction of Lent and Brown using a longitudinal data set of 195 former counseling clients. Our results showed that…

  9. Initial Scale Development of the Contextual Support for Post-Secondary Planning Scales

    ERIC Educational Resources Information Center

    Ali, Saba Rasheed; Martens, Jessica Kelly; Button, Christopher; Larma, Nicholas C.

    2011-01-01

    Vocational psychologists and career theorists have articulated the importance of social support in the development of career plans for high school youth. More recently, Lent, Brown, and Hackett carefully articulated the location of contextual supports in the Social Cognitive Career Theory (SCCT) framework. However, there is a paucity of research…

  10. Applying Social Cognitive Career Theory to Predict Interests and Choice Goals in Statistics among Spanish Psychology Students

    ERIC Educational Resources Information Center

    Blanco, Angeles

    2011-01-01

    This study investigated the usefulness of social cognitive career theory--SCCT (Lent, Brown, and Hackett, 1994) in predicting interests and goals relating to statistics among psychology students. The participants were 1036 Spanish students who completed measurements of statistics-related mastery experiences, self-efficacy, outcome expectations,…

  11. The Influence of Gender, Generation Level, Parents' Education Level, and Perceived Barriers on the Educational Aspirations of Mexican American High School Students

    ERIC Educational Resources Information Center

    Ojeda, Lizette; Flores, Lisa Y.

    2008-01-01

    A portion of social-cognitive career theory (R. W. Lent, S. D. Brown, & G. Hackett, 1994) was tested by examining contextual factors related to the educational aspirations of 186 Mexican American high school students. A 3-step hierarchical regression analysis was conducted to determine the influence of gender, generation level, parents'…

  12. Perceived Social Status and Learning Experiences in Social Cognitive Career Theory

    ERIC Educational Resources Information Center

    Thompson, Mindi N.; Dahling, Jason J.

    2012-01-01

    The purpose of this study was to test a model based on Social Cognitive Career Theory (Lent, Brown, & Hackett, 1994) that placed perceived social status as an antecedent of career-related learning experiences, self-efficacy, and outcome expectations. Gender was included in the present model and results indicated that gender related as expected to…

  13. Career Counseling for Women Preparing to Leave Abusive Relationships: A Social Cognitive Career Theory Approach

    ERIC Educational Resources Information Center

    Wachter Morris, Carrie A.; Shoffner, Marie F.; Newsome, Deborah W.

    2009-01-01

    Career counselors work with people from varied segments of society. For battered women, some of the challenges they face from intimate partner violence may significantly influence their career exploration and decision making. Social cognitive career theory (SCCT; R. W. Lent, S. D. Brown, & G. Hackett, 1994) is a framework that has important…

  14. Social Cognitive Predictors of the Interests and Choices of Computing Majors: Applicability to Underrepresented Students

    ERIC Educational Resources Information Center

    Lent, Robert W.; Lopez, Frederick G.; Sheu, Hung-Bin; Lopez, Antonio M., Jr.

    2011-01-01

    In a replication and extension of earlier research, we examined the explanatory adequacy of the social cognitive choice model (Lent, Brown, & Hackett, 1994) in a sample of 1404 students majoring in a variety of computing disciplines at 23 historically Black and 27 predominantly White universities. Participants completed measures of self-efficacy,…

  15. The Role of Career Barriers in High School Students' Career Choice Behavior in Taiwan

    ERIC Educational Resources Information Center

    Tien, Hsiu-Lan Shelley; Wang, Ying-Fen; Liu, Ling-Chun

    2009-01-01

    The purpose of this study was to examine the role of career barriers in social cognitive career theory (R. W. Lent, S. D. Brown, & G. Hackett, 1994). The participants were 584 high school students in Taiwan, Republic of China. The gender differences in perceived career barriers and career self-efficacy were significant. Results of hierarchical…

  16. The Ongoing Social Construction of the Counseling for Work and Relationship Perspective

    ERIC Educational Resources Information Center

    Richardson, Mary Sue

    2012-01-01

    This rejoinder to the three reactions papers by Blustein (2012), Byars-Winston (2012), and Lent (2012) focuses first on the issue of what is old and what is new about the counseling for work and relationship perspective. This includes the issue of holism, the influence of contextualism, and the designation of new categories and a new discourse for…

  17. Facing the Issues: Challenges, Censorship, and Reflection through Dialogue

    ERIC Educational Resources Information Center

    Lent, ReLeah Cossett

    2008-01-01

    ReLeah Cossett Lent provides practical advice for ensuring that books are kept on shelves and in classrooms for students to read. She outlines steps for creating professional learning communities that engage with censorship issues and prepare schools to deal with book challenges in thoughtful, supportive ways. (Contains 4 figures.)

  18. Prospective First-Generation College Students: A Social-Cognitive Perspective

    ERIC Educational Resources Information Center

    Gibbons, Melinda M.; Borders, L. DiAnne

    2010-01-01

    The authors investigated differences in college-going expectations of middle school students who would be the 1st in their families to attend college. Social-cognitive career theory (SCCT; R. W. Lent, S. D. Brown, & G. Hackett, 1994) was used to examine college-related expectations in 272 seventh-grade students. Differences were found between…

  19. The Social Cognitive Model of Job Satisfaction among Teachers: Testing and Validation

    ERIC Educational Resources Information Center

    Badri, Masood A.; Mohaidat, Jihad; Ferrandino, Vincent; El Mourad, Tarek

    2013-01-01

    The study empirically tests an integrative model of work satisfaction (0280, 0140, 0300 and 0255) in a sample of 5,022 teachers in Abu Dhabi in the United Arab Emirates. The study provided more support for the Lent and Brown (2006) model. Results revealed that this model was a strong fit for the data and accounted for 82% of the variance in work…

  20. Longitudinal Test of the Social Cognitive Model of Choice in Engineering Students at Historically Black Universities

    ERIC Educational Resources Information Center

    Lent, Robert W.; Sheu, Hung-Bin; Gloster, Clay S.; Wilkins, Gregory

    2010-01-01

    We tested the social cognitive model of choice (Lent, Brown, & Hackett, 1994) using a longitudinal design. Participants were 116 students taking beginning engineering courses at two historically Black universities. They completed measures of self-efficacy, outcome expectations, interests, goals, and environmental supports and barriers near the end…

  1. Evaluating the Student Loan Fund of Thailand

    ERIC Educational Resources Information Center

    Tangkitvanich, Somkiat; Manasboonphempool, Areeya

    2010-01-01

    The Thai higher education sector has expanded quickly during the past decade, making a transition from an elitist to a mass institution. A driving force behind the expansion was believed to be the Student Loan Fund (SLF), introduced in 1996. During the first 10 years of its operation, the SLF has lent to more than 2.6 million students, with the…

  2. Overcoming Textbook Fatigue: 21st Century Tools to Revitalize Teaching and Learning

    ERIC Educational Resources Information Center

    Lent, ReLeah Cossett

    2012-01-01

    Go beyond a one-size-fits-all approach to teaching, and discover how shifting textbooks from "sole source" to just another resource revitalizes your practice, improves student achievement, and meets Common Core State Standards. Veteran teacher and literacy expert ReLeah Cossett Lent explains that how you use textbooks makes a huge difference in…

  3. Longitudinal Test of a Social Cognitive Model of Academic and Life Satisfaction

    ERIC Educational Resources Information Center

    Singley, Daniel B.; Lent, Robert W.; Sheu, Hung-Bin

    2010-01-01

    The authors tested a social cognitive model of academic and overall life satisfaction in a sample of 769 university students. The predictors, drawn from Lent's unifying perspective on well-being and psychosocial adjustment, included social cognitive (academic self-efficacy, goal progress, social support) and personality (trait positive affect)…

  4. Family Quality of Life Empowered by Family-Oriented Support

    ERIC Educational Resources Information Center

    Schippers, Alice; van Boheemen, Marleen

    2009-01-01

    Professional services for persons with intellectual disabilities (ID) have begun to attach more importance to their environment. The concept of (family-related) quality of life proved to link very well with this idea and lent itself to constructing and evaluating services. One outcome was the emergence of equal partnerships between families,…

  5. Effects of Social Supports on the Career Choice Consideration of Chinese Farmers: A Social Cognitive Perspective

    ERIC Educational Resources Information Center

    Zhao, Li

    2012-01-01

    Drawing from social cognitive career theory (Lent, Brown, & Hackett, 1994), this study explored social supports' influence on the career choice consideration of farmers during China's current process of urbanization. A questionnaire was designed based on interviews with 140 people and a pretest with a sample of 419 participants. A total of 628…

  6. Social Cognitive Predictors of Academic Adjustment and Life Satisfaction in Portuguese College Students: A Longitudinal Analysis

    ERIC Educational Resources Information Center

    Lent, Robert W.; Taveira, Maria do Ceu; Sheu, Hung-Bin; Singley, Daniel

    2009-01-01

    A social cognitive model of well-being [Lent, R. W. (2004). Toward a unifying theoretical and practical perspective on well-being and psychosocial adjustment. "Journal of Counseling Psychology," 51, 482-509.] was adapted to the context of academic adjustment and tested using a longitudinal design. Participants were 252 students at a…

  7. Social Cognitive and Cultural Orientation Predictors of Well-Being in Asian American College Students

    ERIC Educational Resources Information Center

    Hui, Kayi; Lent, Robert W.; Miller, Matthew J.

    2013-01-01

    This study examined the predictive utility of Lent and Brown's social cognitive model of educational and work well-being with a sample of Asian American college students, indexing well-being in terms of academic and social domain satisfaction. In addition, we examined the role of acculturation and enculturation as culture-specific predictors of…

  8. The Development and Initial Validation of Social Cognitive Career Theory Instruments to Measure Choice of Medical Specialty and Practice Location

    ERIC Educational Resources Information Center

    Rogers, Mary E.; Creed, Peter A.; Searle, Judy

    2009-01-01

    Social cognitive career theory served as the basis for the instrument development for scales assessing self-efficacy, outcome expectations, and goals to predict medical career choice. Lent and Brown's conceptualization of social cognitive constructs guided the development of items to measure choice of medical specialty and practice location. Study…

  9. The Ongoing Social Construction of the Counseling for Work and Relationship Perspective

    ERIC Educational Resources Information Center

    Richardson, Mary Sue

    2012-01-01

    This rejoinder to the three reactions papers by Blustein (2012), Byars-Winston (2012), and Lent (2012) focuses first on the issue of what is old and what is new about the counseling for work and relationship perspective. This includes the issue of holism, the influence of contextualism, and the designation of new categories and a new discourse for…

  10. Social Cognitive Predictors of the Interests and Choices of Computing Majors: Applicability to Underrepresented Students

    ERIC Educational Resources Information Center

    Lent, Robert W.; Lopez, Frederick G.; Sheu, Hung-Bin; Lopez, Antonio M., Jr.

    2011-01-01

    In a replication and extension of earlier research, we examined the explanatory adequacy of the social cognitive choice model (Lent, Brown, & Hackett, 1994) in a sample of 1404 students majoring in a variety of computing disciplines at 23 historically Black and 27 predominantly White universities. Participants completed measures of self-efficacy,…

  11. Social Cognitive Career Theory and the Prediction of Interests and Choice Goals in the Computing Disciplines

    ERIC Educational Resources Information Center

    Lent, Robert W.; Lopez, Antonio M., Jr.; Lopez, Frederick G.; Sheu, Hung-Bin

    2008-01-01

    We tested the fit of the social cognitive choice model [Lent, R.W., Brown, S.D., & Hackett, G. (1994). "Toward a unifying social cognitive theory of career and academic interest, choice, and performance [Monograph]." "Journal of Vocational Behavior," 45, 79-122] to the data across gender, educational level, and type of university among students in…

  12. Longitudinal Relations of Self-Efficacy to Outcome Expectations, Interests, and Major Choice Goals in Engineering Students

    ERIC Educational Resources Information Center

    Lent, Robert W.; Sheu, Hung-Bin; Singley, Daniel; Schmidt, Janet A.; Schmidt, Linda C.; Gloster, Clay S.

    2008-01-01

    We examined the nature of the temporal relations among the core person variables in the social cognitive model of academic and career choice [Lent, R. W., Brown, S. D., & Hackett, G. (1994). Toward a unifying social cognitive theory of career and academic interest, choice, and performance [Monograph]. "Journal of Vocational Behavior," 45,…

  13. Field experience with gas turbine meters

    SciTech Connect

    Hall, W.H.

    1984-04-01

    This paper discusses a company's experience and problems with turbine meters in a large offshore system. With the increased cost and decreasing reserves of natural gas, greater demands will be placed on gas measurement. Turbine meters have lent themselves well to the task and will continue to find more applications in the natural gas industry.

  14. Relationships between College Knowledge and College-Going Beliefs of Eighth Grade Students

    ERIC Educational Resources Information Center

    Wisely, Lynn Woodward

    2013-01-01

    This study examined the relationships of college knowledge and parent education level with these college-going beliefs: (a) self-efficacy, (b) outcome expectations, (c) likelihood both to go to and graduate from college, (d) choice intentions, and (e) educational goals. Social Cognitive Career Theory (Lent, Brown, & Hackett, 1994) provided the…

  15. Mexican American Middle School Students' Goal Intentions in Mathematics and Science: A Test of Social Cognitive Career Theory

    ERIC Educational Resources Information Center

    Navarro, Rachel L.; Flores, Lisa Y.; Worthington, Robert L.

    2007-01-01

    This study examined whether sociocontextual and sociocognitive variables explained the math/science goals of 409 Mexican American youth using a modified version of R. W. Lent, S. D. Brown, and G. Hackett's (1994) social cognitive career theory. Results from structural equation modeling indicated that the hypothesized model explained a significant…

  16. Math and Science Social Cognitive Variables in College Students: Contributions of Contextual Factors in Predicting Goals

    ERIC Educational Resources Information Center

    Byars-Winston, Angela M.; Fouad, Nadya A.

    2008-01-01

    This study investigated the influence of two contextual factors, parental involvement and perceived career barriers, on math/science goals. Using social cognitive career theory (SCCT; Lent, Brown, & Hackett, 1994), a path model was tested to investigate hypothesized relationships between math- and science-related efficacy beliefs (i.e., task and…

  17. Predicting the Math/Science Career Goals of Low-Income Prospective First-Generation College Students

    ERIC Educational Resources Information Center

    Garriott, Patton O.; Flores, Lisa Y.; Martens, Matthew P.

    2013-01-01

    The present study used social cognitive career theory (SCCT; Lent, Brown, & Hackett, 1994) to predict the math/science goal intentions of a sample of low-income prospective first-generation college students (N = 305). Structural equation modeling was used to test a model depicting relationships between contextual (i.e., social class, learning…

  18. Developing Effective Managers.

    ERIC Educational Resources Information Center

    Roberts, T.J.

    In this introductory work, the main principles on which British companies are basing management development programs are presented, and stages in assuring a supply of effective managerial talent are set forth: stages in assuring a supply of effective managerial t"lent are set forth: program planning based on clear objectives and…

  19. Attending to Place, Race, and Community: Trans-Local Partnering between Scholars and Activists in Central Appalachia and the Black Belt South

    ERIC Educational Resources Information Center

    Harris, Rosalind; Bernard, Marcus; Mullinax, Maureen; Worthen, Dreamal; Finch, Sokoya; Womack, Veronica

    2012-01-01

    The communities in the Black Belt South and Central Appalachian regions in the United States share long histories of persistent subjugation. Both regions also have strong traditions of partnerships between grassroots activists and scholars--partnerships that have, at times, lent resilient responses to political, economic and cultural challenges,…

  20. The acquisition process of musical tonal schema: implications from connectionist modeling

    PubMed Central

    Matsunaga, Rie; Hartono, Pitoyo; Abe, Jun-ichi

    2015-01-01

    Using connectionist modeling, we address fundamental questions concerning the acquisition process of musical tonal schema of listeners. Compared to models of previous studies, our connectionist model (Learning Network for Tonal Schema, LeNTS) was better equipped to fulfill three basic requirements. Specifically, LeNTS was equipped with a learning mechanism, bound by culture-general properties, and trained by sufficient melody materials. When exposed to Western music, LeNTS acquired musical ‘scale’ sensitivity early and ‘harmony’ sensitivity later. The order of acquisition of scale and harmony sensitivities shown by LeNTS was consistent with the culture-specific acquisition order shown by musically westernized children. The implications of these results for the acquisition process of a tonal schema of listeners are as follows: (a) the acquisition process may entail small and incremental changes, rather than large and stage-like changes, in corresponding neural circuits; (b) the speed of schema acquisition may mainly depend on musical experiences rather than maturation; and (c) the learning principles of schema acquisition may be culturally invariant while the acquired tonal schemas are varied with exposed culture-specific music. PMID:26441725

  1. 77 FR 30995 - Permits; Foreign Fishing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-24

    ... 0648-XC034 Permits; Foreign Fishing AGENCY: National Marine Fisheries Service (NMFS), National Oceanic... engage in fishing consisting solely of transporting fish or fish products at sea from a point within the... 18, 2012. Rebecca Lent, Director, Office of International Affairs, National Marine Fisheries Service...

  2. A Validation Study of the Thinking Styles Inventory: Implications for Gifted Education.

    ERIC Educational Resources Information Center

    Dai, David Yun; Feldhusen, John F.

    1999-01-01

    A study involving 96 gifted adolescents examined internal and external validity of the Thinking Styles Inventory (TSI) within the framework of Sternberg's (1988) theory of mental self-government. Results provided evidence of the external discriminant validity but lent only partial support to the internal validity of the instrument. (Author/CR)

  3. Corporations Can Be Real Angels When It Comes to Financing School Construction.

    ERIC Educational Resources Information Center

    Gonder, Peggy Odell

    1982-01-01

    Details cooperative agreements to finance new schools drawn up by growing school districts in Colorado and the corporations whose activities are responsible for that growth. The developers of an oil shale project and a tract housing project lent school districts money under very favorable terms. (JM)

  4. Family Factors Associated with Sixth-Grade Adolescents' Math and Science Career Interests

    ERIC Educational Resources Information Center

    Turner, Sherri L.; Steward, Jason C.; Lapan, Richard T.

    2004-01-01

    This study tested a causal model, based on social cognitive career theory (SCCT; R. W. Lent, S. D. Brown, & G. Hackett, 1994, 2000), of math and science career interests among 6th-grade adolescents (N = 318). Consistent with SCCT, it was found that career gender-typing, mother's and father's support for pursuing math and science careers, as well…

  5. Gender in the Development of Career Related Learning Experiences

    ERIC Educational Resources Information Center

    Williams, Christine Marie

    2010-01-01

    Social Cognitive Career Theory (SCCT; Lent, Brown, & Hackett, 1994) delineates the ways in which social forces may influence women's career development and create gender segregation in different types of occupations (see Betz, 2007 for a review). However, a number of questions remain, specifically in regards to how social forces may shape the core…

  6. Ethical and Moral Dimensions of the Professionalization of Teachers: Lessons To Be Learned from Doctors and Lawyers.

    ERIC Educational Resources Information Center

    Smith, Timothy H.

    In response to greater public awareness and concern, members of the legal and medical professions have begun to acknowledge that they have leadership roles to play in the shaping of public policies affecting the common good. The rapid pace of social change and scientific development has lent a new sense of urgency to the need for these two…

  7. 3 CFR 8923 - Proclamation 8923 of December 31, 2012. 150th Anniversary of the Emancipation Proclamation

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    .... Slavery still suspended the possibility of an America where life and liberty were the birthright of all... African Americans, giving new strength to liberty's cause. And with that document, President Lincoln lent... choose not only to remember, but also to make our own. Let us begin this new year by renewing our...

  8. Role of Family Background, Student Behaviors, and School-Related Beliefs in Predicting High School Dropout

    ERIC Educational Resources Information Center

    Parr, Alyssa K.; Bonitz, Verena S.

    2015-01-01

    The authors' purpose was to test a parsimonious model derived from social cognitive career theory (R. W. Lent, S. D. Brown, & G. Hackett, 1994) and expectancy value theory (J. S. Eccles & A. Wigfield, 2002) that integrates groups of variables (demographic background, student behaviors, and school-related beliefs) with the goal of…

  9. High order aberration and straylight evaluation after cataract surgery with implantation of an aspheric, aberration correcting monofocal intraocular lens

    PubMed Central

    Kretz, Florian T A; Tandogan, Tamer; Khoramnia, Ramin; Auffarth, Gerd U

    2015-01-01

    AIM To evaluate the quality of vision in respect to high order aberrations and straylight perception after implantation of an aspheric, aberration correcting, monofocal intraocular lens (IOL). METHODS Twenty-one patients (34 eyes) aged 50 to 83y underwent cataract surgery with implantation of an aspheric, aberration correcting IOL (Tecnis ZCB00, Abbott Medical Optics). Three months after surgery they were examined for uncorrected (UDVA) and corrected distance visual acuity (CDVA), contrast sensitivity (CS) under photopic and mesopic conditions with and without glare source, ocular high order aberrations (HOA, Zywave II) and retinal straylight (C-Quant). RESULTS Postoperatively, patients achieved a postoperative CDVA of 0.0 logMAR or better in 97.1% of eyes. Mean values of high order abberations were +0.02±0.27 (primary coma components) and -0.04±0.16 (spherical aberration term). Straylight values of the C-Quant were 1.35±0.44 log which is within normal range of age matched phakic patients. The CS measurements under mesopic and photopic conditions in combination with and without glare did not show any statistical significance in the patient group observed (P≥0.28). CONCLUSION The implantation of an aspherical aberration correcting monofocal IOL after cataract surgery resulted in very low residual higher order aberration (HOA) and normal straylight. PMID:26309872

  10. Successful Restoration of Visual Acuity with an Extended Range of Vision Intraocular Lens after Multifocal Laser Ablation.

    PubMed

    Black, Sondra

    2016-01-01

    As our baby boomer population is aging and developing cataracts, so are our post-LASIK patients. These patients underwent LASIK surgery as they wished to be spectacle-free and are hoping to remain so after intraocular lens (IOL) surgery. Unfortunately, very little information is available regarding the suitability of presbyopia correcting IOLs for post-LASIK patients. This case represents successful implantation of an extended range of vision IOL in a 59-year-old patient who underwent multifocal ablation excimer laser surgery 12 years before. Emmetropia was targeted for the dominant eye and -0.5 D for the fellow eye. The 13 month follow-up after bilateral implantation of the TECNIS Symfony IOL revealed an uncorrected visual acuity of 20/25 for distance, 20/20 for intermediate and 20/16 for near. The patient is very happy and did not report any visual symptoms when asked. This successful case should encourage surgeons to consider implanting an extended range of vision IOLs in post-LASIK patients.

  11. Successful Restoration of Visual Acuity with an Extended Range of Vision Intraocular Lens after Multifocal Laser Ablation

    PubMed Central

    Black, Sondra

    2016-01-01

    As our baby boomer population is aging and developing cataracts, so are our post-LASIK patients. These patients underwent LASIK surgery as they wished to be spectacle-free and are hoping to remain so after intraocular lens (IOL) surgery. Unfortunately, very little information is available regarding the suitability of presbyopia correcting IOLs for post-LASIK patients. This case represents successful implantation of an extended range of vision IOL in a 59-year-old patient who underwent multifocal ablation excimer laser surgery 12 years before. Emmetropia was targeted for the dominant eye and −0.5 D for the fellow eye. The 13 month follow-up after bilateral implantation of the TECNIS Symfony IOL revealed an uncorrected visual acuity of 20/25 for distance, 20/20 for intermediate and 20/16 for near. The patient is very happy and did not report any visual symptoms when asked. This successful case should encourage surgeons to consider implanting an extended range of vision IOLs in post-LASIK patients. PMID:28101037

  12. Visual results following implantation of a refractive multifocal IOL in one eye and a diffractive multifocal IOL in the contralateral eye.

    PubMed

    Goes, Frank Joseph

    2008-03-01

    To assess binocular visual results in patients who were scheduled to undergo cataract/refractive lens exchange with multifocal IOL implantation using a "mix & match" approach. This prospective study enrolled 40 eyes of 20 patients aged between 44 and 78 years (median age = 58.1 years) implanted with a refractive multifocal IOL (ReZoom) in their dominant eye and a diffractive multifocal IOL (Tecnis) in their non-dominant eye. Near, intermediate, and distance vision were assessed at 2 months following implantation. Patients underwent refractive lens exchange or cataract surgery in the dominant eye first, followed by the non-dominant eye 1 to 2 weeks later. Emmetropia was the goal for all surgeries. Preoperatively, the mean spherical equivalent refraction was +2.019 +/- 1.417 diopters (D) (median: +2.063 D). The mean binocular distance decimal visual acuity was 1.06 +/- 0.60 D, the mean binocular intermediate decimal visual acuity was 0.50 +/- 0.90 D, and the mean binocular near decimal visual acuity was 1.10 +/- 0.40 D. Preliminary visual outcomes in this series of patients indicate good results at all distances.

  13. Comparison of pseudophakic retinal straylight in spherical/aspherical and hydrophobic/hydrophilic intraocular lens

    PubMed Central

    Tang, Yong; Song, Hui; Chen, Jing; Tang, Xin

    2015-01-01

    AIM To study the potential reasons of increased straylight in pseudophakic eyes. METHODS Cross-sectional study. Seventy patients diagnosed as bilateral age-related cataract and implanted with Tecnis ZA9003, Sensar AR40e, SA60AT, XLSTABI ZO or Akeros AO intraocular lens (IOL) were enrolled in this research. Straylight was measured by a C-Quant straylight meter three to four weeks postoperatively. Five different modalities of IOL, including spherical/aspherical optics and hydrophobic/hydrophilic material were tested in this study. Normal as well as dilated pupils were used. The main outcome variable for straylight measurement was the logarithmic straylight parameter, log(s). RESULTS The straylight parameter increased significantly after pupil dilation (P<0.05). Straylight of aspherical IOL was significantly higher after pupil dilation (P<0.05) compared to spherical IOL. In normal pupil, straylight of hydrophobic IOL was significant higher when compared with hydrophilic IOL (P<0.05). CONCLUSION Straylight and visual acuity stand for the different aspects of visual function. Several factors including pupil diameter, optic material, aspherical design of IOL influence intraocular light scattering in pseudophakic eyes. Further investigation was needed to study the impact of optic material and optic surface design on pseudophakic straylight. PMID:26682163

  14. Refractive index and its impact on pseudophakic dysphotopsia

    PubMed Central

    Radmall, Bryce R; Floyd, Anne; Oakey, Zack; Olson, Randall J

    2015-01-01

    Purpose It has been shown that the biggest dissatisfier for uncomplicated cataract surgery patients is pseudophakic dysphotopsia (PD). While edge design of an intraocular lens (IOL) impacts this problem, refractive index is still controversial as to its impact. This retrospective cohort study was designed to determine the role of increasing refractive index in PD. Patients and methods This study was conducted at the John A. Moran Eye Center, University of Utah, USA. A retrospective chart review identified patients who received one of two hydrophobic acrylic single piece IOLs (AcrySof WF SP [SN60WF] or Tecnis SP [ZCB00]), which differed mainly by refractive index (1.55 versus 1.47). Eighty-seven patients who had received implantation of a one-piece hydrophobic acrylic IOL were enrolled. Patients were included if the surgery had been uncomplicated and took place at least a year before study participation. All eligible patients had 20/20 best corrected vision, without any disease known to impact visual quality. In addition to conducting a record review, the enrolled patients were surveyed for PD, using a modified National Eye Institute Visual Function questionnaire, as well as for overall satisfaction with visual quality. Results Statistical analysis demonstrated no difference between the two cohorts regarding PD, general visual function, and overall visual satisfaction. Conclusion The study suggests that with the two IOLs assessed, increasing the refractive index does not increase incidence of PD or decrease overall visual satisfaction. PMID:26229427

  15. Interaction of intraocular lenses with fibronectin and human lens epithelial cells: Effect of chemical composition and aging.

    PubMed

    Tortolano, Lionel; Serrano, Carole; Jubeli, Emile; Saunier, Johanna; Yagoubi, Najet

    2015-12-01

    The aim of this study is to investigate in vitro interactions between hydrophobic acrylate intraocular lenses (IOLs) and their biological environment. The influence of lens chemical composition and aging on fibronectin (FN) adsorption and on IOLs cytotoxicity on human lens epithelial cells was examined. Cytotoxicity of acrylate monomers used in IOLs manufacture was also investigated. Four different IOLs were included in the study: Acrysof(®), Tecnis(®), EnVista(®), and iSert(®). Implants were artificially aged in a xenon arc chamber to simulate 2 years of light exposure. Fibronectin adsorption on IOL surface was quantified using ELISA and correlated to surface roughness determined with AFM. Direct contact cytotoxicity was determined with the MTT assay and cell morphology was observed with light microscopy. Results showed that fibronectin adsorption did not differ significantly among IOLs, whatever their chemical composition. Moreover, aging conditions did not impact fibronectin adsorption. All IOLs were biocompatible even after applying 2-year aging conditions, with cell viability higher than 70%. Five acrylate monomers appeared to be toxic in the range of concentrations tested, but no monomer release from the IOLs could be detected during accelerated 2-year incubation with saline solution. This study did not reveal an influence of chemical composition and aging on protein adsorption and on biocompatibility.

  16. Observation de l'interaction entre atome et surface en cellule de vapeur submicrométrique

    NASA Astrophysics Data System (ADS)

    Dutier, G.; Saltiel, S.; Bloch, D.; Ducloy, M.; Papoyan, A.; Sarkisyan, D.

    2002-06-01

    Sur une cellule de vapeur d'épaisseur submicrométrique ( 300 nm), les spectres d'absorption linéaire se révèlent très peu sensibles à l'effet Doppler (les effets transitoires favorisent fortement les atomes lents), et font apparaître les effets de l'interaction van der Waals à longue portée entre atome-surface. L'étude, entreprise d'abord sur la raie de résonance D1 de Cs, est poursuivie sur une transition à deux photons vers le niveau Cs 6(D{3/2}) résonnant avec la surface de YAG de la fenêtre. Elle ouvre diverses perspectives, notamment la détection d'états liés par un puits de potentiel induit par la surface.

  17. [Triatoma vandae sp.n. of the oliveirai complex from the State of Mato Grosso, Brazil (Hemiptera: Reduviidae: Triatominae)].

    PubMed

    Carcavallo, Rodolfo U; Jurberg, José; Rocha, Dayse da Silva; Galvao, Cleber; Noireau, François; Lent, Herman

    2002-07-01

    There are several specific complexes belonging to the genus Triatoma Laporte, 1832, which are generally associated to specific geographic areas. Recent publications have linked the oliveirai complex to ecosystems of Mato Grosso, which are also present in other Brazilian states and even in other bordering countries as eastern Paraguay. The study of the abundant material collected during the last years allowed the description of several new species of the oliveirai complex: T. jurbergi Carcavallo, Galvão Lent, 1998; T. baratai Carcavallo Jurberg, 2000 and T. klugi Carcavallo, Jurberg, Lent Galvão, 2001. Another new species belonging to the same complex is described here as T. vandae sp.n. It originates from the state of Mato Grosso, and has been reared in the insectary of the Laboratório Nacional e Internacional de Referência em Taxonomia de Triatomíneos, Departamento de Entomologia, Instituto Oswaldo Cruz-Fiocruz, Rio de Janeiro.

  18. Complex carbohydrates in the dietary management of patients with glycogenosis caused by glucose-6-phosphatase deficiency.

    PubMed

    Smit, G P; Ververs, M T; Belderok, B; Van Rijn, M; Berger, R; Fernandes, J

    1988-07-01

    Carbohydrates with digestion characteristics between those of lente uncooked starches and rapidly digestible oligosaccharides were administered in a dose of 1.5 g/kg body weight to five patients with glycogenosis from glucose-6-phosphatase deficiency. Postprandial duration of normoglycemia and concentrations of blood insulin and lactate were determined. Uncooked barley groats in water, or incorporated in a meal turned out to behave as lente carbohydrates. Uncooked couscous in water, couscous incorporated in a meal, and partially cooked macaroni given as a meal behaved as semilente carbohydrates as compared with uncooked cornstarch and glucose. The in vitro determination of the digestibility index along with the in vivo tolerance test enables us to choose and incorporate semilente carbohydrates in the day-time treatment of patients.

  19. Mercury Cadmium Selenide for Infrared Detection

    DTIC Science & Technology

    2013-06-01

    were grown using elemental mercury (Hg), cadmium (Cd), and selenium (Se) sources. The beam equiva- lent pressure ( BEP ) emanating from all sources was...flux), the BEP measured for the cracker source was found to vary with the cracking zone temperature, tracking with the data found in Ref. 7. This sug...The Se BEP measured for the typical cracking zone temperature of 800 C was found to be close to a factor of two lower than at the typical effusion cell

  20. Review of Cytoskeleton Research in Cell Differentiation and Development.

    DTIC Science & Technology

    1987-09-10

    mined stem cells of normal lineages and cytokeratins are a family of approximate- they are composed of malignant cells , an, lv 20 polypeptides which... cell to become a normnal stem cell . be characterized by the combinations of This was demonstrated ’rv placing embrv-- basic and acidic cytokeratins...these proteins are exel- tat the malignant stem cell was incor- lent markers for the different routes of p4 rated Into the develeping enbrvu and it

  1. Fluid Dynamic Mechanisms and Interactions within Separated Flows and Their Effects on Missile Aerodynamics

    DTIC Science & Technology

    1983-05-01

    incompressihle potential flow problems suitable for this method include the following: (1) Free overfall ; (2) Flow past a sluice gate; (3) Flow past a sharp...of recompression-reattachment of a turbu- lent free shear layer , it was learned that this same integral analysis can be employed to study the base ...approaches zero as the free stream Mach number increases toward unity, while the base pressure coefficient decreases toward more negative values. It was

  2. Inventions, Patents, and Related Matters

    DTIC Science & Technology

    1964-02-06

    in mantaining research records. Notel;ooks.12 DO Entries will be made in an officially authorized bound notebook. Entries will be made in ink. All...specialized laboratory tool , it is inadvisable to ap- ply for patent, particularly if a number of equiva- lent prior-art ways of satisfactorily...of materials, plant layout and tooling , to the extent-that such information is not readily disclosed by inspection or analysis of the product

  3. Environmental Compliance Assessment System Army National Guard (ECAS- ARNG)

    DTIC Science & Technology

    1993-09-01

    34* Total Metal - the sum of the concentrations of mass of copper, nickel, chromium , and zinc (40 CFR 413.02). "* Total Solids - the materials in sewage...3X13) 413.14(f)). (NOTE: Electroplating of common metals refers to electroplating with copper, nickel, chromium , zinc, tin, lead. cadmium, iron...absence of chelating agents in the pretreatment process, that after reduction of hexavz’lent chromium wastes, and after neutralization using calcium

  4. CrossTalk: The Journal of Defense Software Engineering. Volume 20, Number 5, May 2007

    DTIC Science & Technology

    2007-05-01

    DIRECTOR PUBLISHER MANAGING EDITOR ASSOCIATE EDITOR ARTICLE COORDINATOR PHONE E-MAIL CROSSTALK ONLINE The Honorable John Grimes Jeff Schwalb Kevin...issue are trademarks of their companies. CrossTalk Online Services: See <www.stsc.hill.af.mil/ crosstalk>, call (801) 777-0857 or e-mail <stsc.web...excel- lent analogy. Today, most people are very competent car shoppers . They use tools such as the Internet, car magazines, buying guides, and lessons

  5. JPRS Report, East Asia, Southeast Asia.

    DTIC Science & Technology

    2007-11-02

    to be realized in a not too distant future. The first-phase realisation of the project was considered as fairly successful , especially those in...managing their business and this posed a setback to their success in business. Datuk Koding, who is also Minister for Industrial and Rural Development...inputs and buy their produce, they were at the mercy of usurers and traders who lent them money at high interest rates and bought their produce at

  6. Recognizing and Understanding Revolutionary Change in Warfare: The Sovereignty of Context

    DTIC Science & Technology

    2006-02-01

    lent his formidable personal authority, as well as the weight of his small but influential Office of Net Assessment in the Office of the Secretary...consequence. As the preceding discussion suggests, this cannot be done by studying past RMAs or ruminating on the nature of transformation. It can be done...impractical to expect more than a small number of military specialists to acquire a deep knowledge of the relevant local societies with their

  7. The Harmon Memorial Lectures in Military History 1959-1987

    DTIC Science & Technology

    1988-01-01

    refusal to change course-for example, his di 3ire to get on with the war against Japan, a compulsion he could never forget-and his desirc to gct on...6. Ernest Taveson, Re ,eemer Nation: The Idea of America sv Millennial Role (Chicago, 1968). 7. lent y May, The Fnjlightevnment in Amenrica (New...themselves under a moral compulsion to refrain from doing what is lawfully ordered of them. If they are under suffi- ciently powerful moral pressure and are

  8. Comparison of Two Hierarchical Routing Protocols for Heterogeneous MANET

    DTIC Science & Technology

    2007-10-01

    révèlent que le protocole H-OLSR est d’un rendement supérieur au protocole H-LANMAR pour la plupart des scénarios de mobilité de groupe qui portent...bien à une topologie de MANET hétérogène du domaine tactique. Nous recourons à des scénarios de mobilité de groupe qui caractérisent l’exploitation

  9. Efficient Server Aided Secure Two Party Function Evaluation with Applications to Genomic Computation

    DTIC Science & Technology

    2016-07-14

    that disease (see section 3.1 for more detail). Then if the partners can each separately evaluate their DNA for a fingerprint of a specific disease...lent to a SNP) and both parties searching whether the disease fingerprint also appears in the server’s DNA . This requires scanning over the entire...medicine uses genomic tests prior to pre- scribing a treatment to ensure its success; – paternity testing uses DNA data to determine whether one

  10. Case report: a tale of two dentures.

    PubMed

    Beckett, H; Sequeira, P

    1998-12-01

    A case is presented where loss of an incisor tooth in a partial denture wearer created an aesthetic emergency. It was not possible to solve this simply by addition of a tooth to the existing denture. Reference to the previous dental history suggested that a further immediate solution might be unwise. The design of the existing denture lent itself to the novel solution of a second denture, retained by elements of the first.

  11. Description and Flow Characterization of Hypersonic Facilities

    DTIC Science & Technology

    1994-08-01

    a space marching algorithm which includes the induced pressure effects of boundary-layer growth from laminar to turbu- lent flow provided the...showing the onset of air liquifaction . decrease in stream Mach number and an increase in stream static pressure. As was the case with air liquefaction...tank, which then induces pressures to locally separate the tunnel boundary layer. Sequential shadowgraph pictures (Fig. 37) 15 AEDC-TR-94-8

  12. Maintenance in Service of High Temperature Parts

    DTIC Science & Technology

    1982-01-01

    ont une cinetique de croissance plus lente, contrl~e par la diffusion du nickel A travers la phase g-NiAI riche en nickel (60 us de NiAI sur IN 100 en...des procedes de soudage conventionrel notasTent sun les surerailiaccs Ac fonderie. Mais l’int~rnt economique est site apparu e la reparation de pieces

  13. Graphidioides subterraneus n. sp. (Nematoda: Trichostrongyloidea) from the South American subterranean rodent Ctenomys talarum Thomas, 1898 (Rodentia: Octodontidae).

    PubMed

    Rossin, M A; Timi, J T; Malizia, A I

    2005-06-01

    A new nematode species, Graphidioides subterraneus n. sp., found in the stomach of C. talarum from Argentina is described. The new species more closely resembles G. mazzai Lent & Freitas, 1935, parasite of Galea leucoblephara from Argentina, and G. kravetzi Sutton & Durette-Desset, 1995, parasite of Holochilus brasiliensis from Uruguay. It can be distinguished by shorter spicules, by the shape of the gubernaculum, by shorter uterine branches, and by a different number of ridges of the synlophe all along the body.

  14. A History of the Little Rock District U. S. Army Corps of Engineers

    DTIC Science & Technology

    1971-01-01

    improveD;lent and flood control . This was the first time that a President had included river controls as part of the goals of his Presidential...by Major General E. M. Markham, Chief of Engineers. The supporters of flood control lost no time in demand- ing flood control action; Senator Bennett...collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources

  15. Sowing Modern SEAD: Reaping Success or Changing Strains

    DTIC Science & Technology

    2005-06-01

    air forces located Iraqi 58“Success from the Air,” Jane’s Defence Weekly, 6 April 1991, 530. 59 Christopher Bolkcom, Military Suppression of Enemy...60 Maj Gen Walter Buchanan, “Air Force Current Operations,” briefing to Congressional Air Power Caucus, Bolling AFB, 12 March 2001, in Christopher ...tactics raised system costs and sustained performance lent SEAD 67 Christopher Bolkcom, Military Suppression of Enemy Air Defenses (SEAD): Assessing

  16. Military Review, September 1994. Volume 74, Number 9

    DTIC Science & Technology

    1994-09-01

    I ederation of Malaysia. wanted the Malaysianl governm~lent to rlvlerseillt Throughout the negotiation process, ethnic senl- all Malaysians , not JUSt...thle Malays. Lee chain- sibiliti’ wer paImon cosdrain. ic ioned a " Malaysian ’’ Malaysia as opplosed to a 1945, race riots and ethnically based...British withdrawal was disastrous. lin nsd te othas si rgon T heeo- Singapore perceived that the Malaysian , triajy, thle PI NA is~l an xample of Sou

  17. Second Topical Meeting on Laser Techniques in the Extreme Ultraviolet.

    DTIC Science & Technology

    1985-01-10

    lasers. Cenfined Plasma Column, S. Suckewer, C. Keane, H. .-Milchborg, C. H. Skinner , and D. Voorhees, Plasma Physics-- 1&.30 AM COFFEE BREAK...and Cr) and carbon (2d = 150 ,) from 80 to 350 eV. Spectrometer configurations composed of variable-line-space IT. J. Watson Research Center, IBM...EUV Une I (Poster Paper) Intensities in Co,.-Laser-Produced Plasmas, C. H. Skinner , C. lent Generation of Tunable Radiation below 100 nm In Keane, H

  18. The Effect of the Summer Training Program on Midshipmen Career Choice at the United States Naval Academy

    DTIC Science & Technology

    2004-03-01

    theory, and social constructionism . It is important to note that the specific names of the traditions and the theories they contain vary from author...parental influence is substituted with a social culture of peers and teachers. Specific research of students and the influence of the academic...Vocational Education Research , 21(4), 3-21. Lent, B. W., Hackett G., & Brown S. D. (1999). A social cognitive view of school- to-work transition. The

  19. National Dam Safety Program. Diascund Reservoir Dam. Inventory Number: VA-12703. New Kent County, Virginia. Phase I Inspection Report.

    DTIC Science & Technology

    1979-03-01

    12703) County: New lent State: Virginia Coordinate.: Lat . 3725.8 Long. 7654.0 Dat. of Insp.ctian: 14 Decanber 1978 Weather: Fair Te.p.rature: 450 p...MO l l SICISNO N O . V I S S I N I A - \\• 7 ~ - -~L:~ - -- ~~ _ No.__ II-U~4~~ - - - ~ . ~~ ‘; • - -4 . • ‘ _ . TESI BORING LOG

  20. Sexual Functioning During Menopause: Schemas, Hormones, and Race

    DTIC Science & Technology

    2010-10-08

    John Wu and Mr. Omar Larco lent their expertise in performing the ELISA hormone assays. I also would like to thank all the individuals who allowed me...theorists have postulated that schema formation may be linked to early attachment experiences ( Bowlby , 1969). Schemas are thought to form at a young...population study. Maturitas, 34(1), 17-23. Bowlby , J. (1969). Attachment and loss (vol 1) Attachment. New York: Basic Books. Bowles, C. (1986

  1. The Anomalous Metalloporphyrin and Chlorophyll a Activated Chemiluminescence of Dimethyldioxetanone. Chemically Initiated Electron-Exchange Luminescence.

    DTIC Science & Technology

    1980-02-26

    on the rate of reaction of decalin hydroperoxide . Moreover, the free-base reaction is not chemilumine- scent. More recently, McCapra reported...Sigma) was also purified by treatment with DDQ. Other metalloporphyrins were prepared by reaction of the appropriate diva- lent metal salt with the...Navy Annapolis, Maryland 21401 Washington, D.C. 20360 1 Naval Ocean Systems Center Defense Documentation Center Attn: Dr. S. Yamamoto , Marine Building

  2. A Review and Evaluation of Integrated Atmospheric Boundary-Layer Models for Maritime Applications.

    DTIC Science & Technology

    1981-11-01

    done in these areas, but most of the questions will probably be resolved within the next few years. Conversely , the entrainment parameterizations are...1981: "The daytime evolutin of the East African jet", J. Atmos.Sci., 38, 114-128. 20. Fairall, C.W., K.L. Davidson and G.E. Schacher, 1982...one degree per hundred meters;, the actual measured spectrum (or extinction coeffi<Lent) will tend to increase. 2 , 3 u Conversely , if one takes a

  3. New Directions for Early Literacy in a Digital Age: The iPad

    ERIC Educational Resources Information Center

    Flewitt, Rosie; Messer, David; Kucirkova, Natalia

    2015-01-01

    In this paper, we discuss how iPads offer innovative opportunities for early literacy learning but also present challenges for teachers and children. We lent iPads to a Children's Centre nursery (3- to 4-year-olds), a primary school reception class (4- to 5-year-olds) and a Special School (7- to 13-year-olds), discussed their potential uses with…

  4. New Directions for Early Literacy in a Digital Age: The iPad

    ERIC Educational Resources Information Center

    Flewitt, Rosie; Messer, David; Kucirkova, Natalia

    2015-01-01

    In this paper, we discuss how iPads offer innovative opportunities for early literacy learning but also present challenges for teachers and children. We lent iPads to a Children's Centre nursery (3- to 4-year-olds), a primary school reception class (4- to 5-year-olds) and a Special School (7- to 13-year-olds), discussed their potential uses with…

  5. Parhadjelia cairinae n. sp. (Nematoda: Habronematoidea: Habronematidae) in the Muscovy duck, Cairina moschata (Linnaeus, 1758) (Aves: Anseriformes: Anatidae), from the area de conservacion Guanacaste, Costa Rica.

    PubMed

    Zhang, Luping; Brooks, Daniel R

    2005-04-01

    A new species of Parahadjelia occurs in the muscovy duck, Cairina moschata (Linnaeus, 1758), from the Area de Conservacion Guanacaste, Costa Rica. The new species differs from Parhadjelia neglecta Lent and Freitas, 1939, in the body size, in the spicules shape and ratio of spicules, and in having 2 pairs of sessile papillae near the tail tip of the male. The characters exhibited by P. neglecta and the new species validate its generic status distinct from Hadjelia.

  6. Whats in Your Estimate at Completion

    DTIC Science & Technology

    2014-04-01

    the influence of contractor overhead costs, general and administrative costs, and cost of money . Add in profit/fee and you get price, which takes...you directly into budget territory: totals, phasing, obligations and expenditures. Thus an EAC discussion should be married with evaluation of a...Time is money , so this is an excel- lent opportunity for the PM to inquire how the contractor schedule risk analysis (SRA) was conducted, and to what

  7. Modeling Turbulent Mixing/Combustion of Bio Agents Behind Detonations: Effect of Instabilities, Dense Clustering, and Trace Survivability

    DTIC Science & Technology

    2017-06-01

    and Stewart , 1990; Williams et al., 1996). In contrast, very few investigations have focused on the effect of presence of particles, either solid or...by means of fine powders. Proc. Combust. Inst., 7, 504. Lee, H.I., and Stewart , D.S. 1990. Calculation of linear detonation instability: One...progresses. This is in excel- lent agreement with the results in literature (Dou et al., 2008; Lee and Stewart , 1990). Also, the peak value of the pressure

  8. A Random Matrix Theory Approach to National Procurement Spending: Applications to the CC130 Hercules Fleet Performance

    DTIC Science & Technology

    2010-08-01

    indicateurs de rendement de haut niveau, ce qui donne à penser que la flotte a une réaction inélastique aux chocs de dépenses. Ces résultats révèlent...celles qui sont observées dans les données ont peu d’effet sur le rendement. Nous pouvons conclure que l’entretien est très robuste ; les chocs de

  9. Sales Training for Army Recruiter Success: Interviews with Excellent Recruiters

    DTIC Science & Technology

    1987-11-01

    merit of an expert modeling system of the skills and strategies used by excel- lent Army recruiters. Neurolinguistic programming (NLP) was used as the...7. AUTHOR(&) 8. CONTRACT OR GRANT NUMBER(s) Steven R. Frieman 9. PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT. PROJECT, TASK U.S...Recruiting 2M AUSTIRACT (rcnttm ame r orw am nssry i Identify by block number) s-This report describes a program of research on communication strategies and

  10. [Brueghel's cripples].

    PubMed

    Keeman, J N Hans

    2011-01-01

    The auction of Brueghel's 'Fight between Carnival and Lent' is the reason for a survey of a group of cripples painted by Brueghel. In the late middle ages and early modern times, cripples and the handicapped who could only move with the aid of crutches were virtually excluded from society. Begging and making music were often the only way they could make a living. Their injuries were not always genuine, often they were feigned to gain sympathy and obtain money more easily.

  11. Rediscovery and New Morphological Data on Two Hassalstrongylus (Nematoda: Heligmonellidae) Coparasitic in the Marsh Rat Holochilus chacarius (Rodentia: Cricetidae) from Argentina.

    PubMed

    Digiani, María Celina; Notarnicola, Juliana; Navone, Graciela T

    2015-10-01

    Two species of Hassalstrongylus Durette-Desset, 1971, coparasitic in Holochilus chacarius Thomas (Rodentia, Cricetidae) and not recorded since their original description in 1937, were newly found in their type host and locality. Hassalstrongylus mazzai (Freitas, Lent and Almeida, 1937) and Hassalstrongylus argentinus (Freitas, Lent and Almeida, 1937) were obtained from Ho. chacarius from 2 different populations: one from Salta Province (northwest Argentina) and another from Chaco Province (northeast Argentina). The species described as Heligmonoides mazzai Freitas, Lent and Almeida, 1937 had been transferred to Hassalstrongylus even though its synlophe had never been studied. We provide the first descriptions and illustrations of the synlophe of males and females of Hassalstrongylus mazzai and the female of H. argentinus and account for morphological and metrical variability. We confirm, through the study of the synlophe, the placement of Hassalstrongylus mazzai in the genus Hassalstrongylus and designate neotypes for the species because the type material deposited by the authors could not be found. Females of both species were morphologically very similar, and a principal components analysis (PCA) performed on some morphometrical characters showed that the body length, uterus length, and an unexpected character as the number of eggs were useful characters in the discrimination of both species.

  12. Tissue compliance meter is a more reproducible method of measuring radiation-induced fibrosis than late effects of normal tissue-subjective objective management analytical in patients treated with intracavitary brachytherapy accelerated partial breast irradiation: results of a prospective trial.

    PubMed

    Wernicke, A Gabriella; Greenwood, Eleni A; Coplowitz, Shana; Parashar, Bhupesh; Kulidzhanov, Fridon; Christos, Paul J; Fischer, Andrew; Nori, Dattatreyudu; Chao, Kun S Clifford

    2013-01-01

    Identification of radiation-induced fibrosis (RIF) remains a challenge with Late Effects of Normal Tissue-Subjective Objective Management Analytical (LENT-SOMA). Tissue compliance meter (TCM), a non-invasive applicator, may render a more reproducible tool for measuring RIF. In this study, we prospectively quantify RIF after intracavitary brachytherapy (IB) accelerated partial breast irradiation (APBI) with TCM and compare it with LENT-SOMA. Thirty-nine women with American Joint Committee on Cancer Stages 0-I breast cancer, treated with lumpectomy and intracavitary brachytherapy delivered by accelerated partial breast irradiation (IBAPBI), were evaluated by two raters in a prospective manner pre-IBAPBI and every 6 months post-IBAPBI for development of RIF, using TCM and LENT-SOMA. TCM classification scale grades RIF as 0 = none, 1 = mild, 2 = moderate, and 3 = severe, corresponding to a change in TCM (ΔTCM) between the IBAPBI and nonirradiated breasts of ≤2.9, 3.0-5.9, 6.0-8.9, ≥9.0 mm, respectively. LENT-SOMA scale employs clinical palpation to grade RIF as 0 = none, 1 = mild, 2 = moderate, and 3 = severe. Correlation coefficients-Intraclass (ICC), Pearson (r), and Cohen's kappa (κ)-were employed to assess reliability of TCM and LENT-SOMA. Multivariate and univariate linear models explored the relationship between RIF and anatomical parameters [bra cup size], antihormonal therapy, and dosimetric factors [balloon diameter, skin-to-balloon distance (SBD), V150, and V200]. Median time to follow-up from completion of IBAPBI is 3.6 years (range, 0.8-4.9 years). Median age is 69 years (range, 47-82 years). Median breast cup size is 39D (range, 34B-44DDD). Median balloon size is 41.2 cc (range, 37.6-50.0 cc), and median SBD is 1.4 cm (range, 0.2-5.5 cm). At pre-IBAPBI, TCM measurements demonstrate high interobserver agreement between two raters in all four quadrants of both breasts ICC ≥ 0.997 (95% CI 0.994-1.000). After 36 months, RIF is graded by TCM scale as 0

  13. Determinants of patient satisfaction and function related to vision following cataract surgery in eyes with no visually consequential ocular co-morbidity.

    PubMed

    Kirwan, Clare; Nolan, John M; Stack, Jim; Moore, Tara C B; Beatty, Stephen

    2015-10-01

    To investigate subjectively reported outcomes following cataract surgery and the relationships between such outcomes in the context of falling thresholds for cataract surgery. Large, private, non-refractive cataract practice, Institute of Eye Surgery, Whitfield Clinic, Waterford, Ireland Pre-operative, intra-operative and post-operative data of 2552 eyes undergoing phacoemulsification and implantation of the Tecnis(R) ZCB00 1-piece intraocular lens (IOL) by a single surgeon between July 2009 and October 2013 was analysed. Patients without visually consequential ocular co-morbidity completed two validated questionnaires, designed to assess subjectively perceived visual functioning and identify symptoms of dysphotopsia following cataract surgery. 54.8 % of questionnaire respondents were entirely satisfied (satisfaction 10/10) post-operatively, with 83.7 % reporting satisfaction of ≥7/10. Satisfaction was positively associated with patient age and negatively associated with spectacle dependence, dysphotopsia, and function related to vision (NEI VF-11) score. The mean (±standard deviation[SD]) dysphotopsia score was 1.36 (±1.9; scale 0-10), with 40 % of respondents reporting no dysphotopsia symptoms and 9.8 % reporting clinically meaningful dysphotopsia. The mean (±SD) National Eye Institute visual function-11 (NEI VF-11) score was 0.33 (±0.53; scale 0-4) and reduced function related to vision was associated with increasing severity of dysphotopsia symptoms. When linear regression was applied, 17.5 % of the variation in functionality was attributable to symptoms of dysphotopsia. Dysphotopsia is an important determinant of a patient having difficulty with vision-related tasks following cataract surgery, and patient satisfaction is positively associated with patient age and negatively associated with spectacle in dependence, dysphotopsia and function related to the vision (NEI VF-11) score.

  14. Visual Outcomes, Quality of Vision, and Quality of Life of Diffractive Multifocal Intraocular Lens Implantation after Myopic Laser In Situ Keratomileusis: A Prospective, Observational Case Series

    PubMed Central

    2017-01-01

    Purpose. To report visual performance and quality of life after implantation of a bifocal diffractive multifocal intraocular lens (MIOL) in postmyopic laser in situ keratomileusis (LASIK) patients. Methods. Prospective, observational case series. Patients with prior myopic LASIK who had implantation of Tecnis ZMA00/ZMB00 MIOL (Abbott Medical Optics) at Hong Kong Sanatorium and Hospital were included. Postoperative examinations included monocular and binocular distance, intermediate and near visual acuity (VA), and contrast sensitivity; visual symptoms (0–5); satisfaction (1–5); spectacle independence rate; and quality of life. Results. Twenty-three patients (27 eyes) were included. No intraoperative complications developed. Mean monocular uncorrected VA at distance, intermediate, and near were 0.13 ± 0.15 (standard deviation), 0.22 ± 0.15, and 0.16 ± 0.15, respectively. Corresponding mean values for binocular uncorrected VA were 0.00 ± 0.10, 0.08 ± 0.13, and 0.13 ± 0.10, respectively. No eyes lost >1 line of corrected distance VA. Contrast sensitivity at different spatial frequencies between operated and unoperated eyes did not differ significantly (all P > 0.05). Mean score for halos, night glare, starbursts, and satisfaction were 1.46 ± 1.62, 1.85 ± 1.69, 0.78 ± 1.31, and 3.50 ± 1.02, respectively. Eighteen patients (78%) reported complete spectacle independence. Mean composite score of the quality-of-life questionnaire was 90.31 ± 8.50 out of 100. Conclusions. Implantation of the MIOL after myopic LASIK was safe and achieved good visual performance. PMID:28133543

  15. Halo and Through-Focus Performance of Four Diffractive Multifocal Intraocular Lenses.

    PubMed

    Vega, Fidel; Alba-Bueno, Francisco; Millán, María S; Varón, Consuelo; Gil, Miguel A; Buil, Jose A

    2015-06-01

    To compare, as a function of pupil size, the through-focus performance and halo features of four diffractive intraocular lenses (IOLs). Three diffractive bifocal IOLs (ReSTOR +2.5 D SV25T0, Tecnis +2.75 D ZKB00, and AT LISA +3.75 D 809M) and a diffractive trifocal IOL (AT LISA tri +3.33 D, +1.66 D 839MP) were tested in vitro in a modified International Organization for Standardization eye model. The modulation transfer function (MTF) at the IOLs' foci was obtained with pupils ranging from 2.0 to 5.0 mm. Through-focus MTF curves (at 50 cycles/mm) were compared among all the IOLs. The halo formation and characteristics were obtained from image analysis. The multifocal IOLs studied in this work showed, at their foci, secondary out-of-focus images, which originate halos and whose characteristics depend on the lens design and pupil size. The smallest halo occurred for the distance focus of the SV25T0. The distance and near foci of the SV25T0 yielded, respectively, the best and lowest optical quality among the studied IOLs. The distance focus of the ZKB00, AT LISA, and AT LISA tri were of similar quality, but the near focus of the ZKB00 outperformed the near foci of the rest of the IOLs. The IOLs' optical performance gradually deteriorates as pupil increases. Differences in the design of the diffractive IOLs translate into differences in optical quality at their foci, through-focus performance, and halo features, which can offer further information to surgeons when selecting which IOL to implant.

  16. Protection of Salivary Function by Concomitant Pilocarpine During Radiotherapy: A Double-Blind, Randomized, Placebo-Controlled Study

    SciTech Connect

    Burlage, Fred R. Roesink, Judith M.; Kampinga, Harm H.; Coppes, Rob P.; Terhaard, Chris; Langendijk, Johannes A.; Luijk, Peter van; Stokman, Monique A.; Vissink, Arjan

    2008-01-01

    Purpose: To investigate the effect of concomitant administration of pilocarpine during radiotherapy for head-and-neck squamous cell carcinoma (HNSCC) on postradiotherapy xerostomia. Methods and Materials: A prospective, double blind, placebo-controlled randomized trial including 170 patients with HNSCC was executed to study the protective effect of pilocarpine on radiotherapy-induced parotid gland dysfunction. The primary objective endpoint was parotid flow rate complication probability (PFCP) scored 6 weeks, 6 months, and 12 months after radiotherapy. Secondary endpoints included Late Effects of Normal Tissue/Somatic Objective Management Analytic scale (LENT SOMA) and patient-rated xerostomia scores. For all parotid glands, dose-volume histograms were assessed because the dose distribution in the parotid glands is considered the most important prognostic factor with regard to radiation-induced salivary dysfunction. Results: Although no significant differences in PFCP were found for the two treatments arms, a significant (p = 0.03) reduced loss of parotid flow 1 year after radiotherapy was observed in those patients who received pilocarpine and a mean parotid dose above 40 Gy. The LENT SOMA and patient-rated xerostomia scores showed similar trends toward less dryness-related complaints for the pilocarpine group. Conclusions: Concomitant administration of pilocarpine during radiotherapy did not improve the PFCP or LENT SOMA and patient-rated xerostomia scores. In a subgroup of patients with a mean dose above 40 Gy, pilocarpine administration resulted in sparing of parotid gland function. Therefore, pilocarpine could be provided to patients in whom sufficient sparing of the parotid is not achievable.

  17. Espectroscopia multi-objeto e imageamento de Abell 586 com GMOS - o estado dinâmico de um aglomerado de galáxias com arcos gravitacionais

    NASA Astrophysics Data System (ADS)

    Cypriano, E. S.; Sodrã©, L., Jr.; Kneib, J.-P.; Campusano, L.

    2003-08-01

    Nesse trabalho é apresentado um estudo do conteúdo de massa do aglomerado de galáxias A586 (z = 0.171) bem como sua distribuição espacial. Isso foi feito a partir de dados de espectroscopia multi-objeto e imageamento obtidos com o instrumento GMOS acoplado ao telescópio Gemini-Norte. A massa desse aglomerado foi estudada a partir da posição dos seus arcos gravitacionais (lentes fortes), da medida estatística da distorção na forma das galáxias de fundo (lentes fracas) e através da dispersão de velocidades de uma amostra de cerca de 30 galáxias pertencentes ao aglomerado (teorema do virial). Os dois primeiros métodos não dependem do estado dinâmico do aglomerado, enquanto que o terceiro sim. Desse modo, comparando seus resultados pode-se estimar o grau de relaxamento desse sistema. Dados de raios X presentes na literatura também serão incluídos nessa análise. Nossos resultados preliminares a partir das técnicas de lentes fracas, mostram que, supondo que a distribuição de massa desse aglomerado seja a de uma esfera isotérmica, espera-se que ele apresente uma dispersão de velocidades de 1330+/-78 km s-1, em contradicao com medidas similares feitas por Dahle et al. 2002 que encontram valores tão altos quanto 1680 km s-1. Já o estudo dinâmico resultou numa dispersão de velocidades de ~950 km s-1.

  18. Quantum Dot Cellular Automata: Computing with Coupled Quantum-Dot Molecules

    NASA Astrophysics Data System (ADS)

    Porod, Wolfgang

    1998-05-01

    We have recently proposed a scheme of using coupled quantum dots to realize digital computing elements.(C. S. Lent, P. D. Tougaw, W. Porod, and G. H. Bernstein, Nanotechnology 4, 49 (1993); C. S. Lent, P. D. Tougaw, and W. Porod, Applied Physics Letters 62, 714 (1993).) Our scheme was inspired by recent work on nanometer-scale lithography in semiconductors which has permitted the construction of quantum dots which may be viewed as artificial atoms; furthermore, the principle of dot-dot coupling has also been demonstrated, thus realizing artificial semiconductor molecules. This talk will review the work of the Notre Dame group on the theory and modeling of cellular arrays of coupled quantum-dot molecules, which we refer to as quantum-dot cellular automata (QCA). We consider inhomogeneous arrays of quantum-dot molecules, where each molecule forms the basic unit in a cellular automaton-type array architecture. These cells (molecules) consists of four or five quantum dots in close enough proximity to enable electron tunneling between dots. Coulomb repulsion between electrons in the cell results in a bistable ground state whose configuration is determined by the configuration of neighboring cells. The electrons tend to occupy antipodal sites in one of two ground-state configurations which may be used to encode binary information. We have demonstrated that Boolean logic gates can be constructed, and simple design rules permit the fabrication of any logic function. The basic principle of QCA operation was demonstrated in recent experiments.(A. O. Orlov, I. Amlani, G. H. Bernstein, C. S. Lent, and G. L. Snider, Science 277, 928, (1997).)

  19. Late Gastrointestinal Toxicity After Dose-Escalated Conformal Radiotherapy for Early Prostate Cancer: Results From the UK Medical Research Council RT01 Trial (ISRCTN47772397)

    SciTech Connect

    Syndikus, Isabel; Morgan, Rachel C.; Sydes, Matthew R.; Graham, John D.; Dearnaley, David P.

    2010-07-01

    Purpose: In men with localized prostate cancer, dose-escalated conformal radiotherapy (CFRT) improves efficacy outcomes at the cost of increased toxicity. We present a detailed analysis to provide further information about the incidence and prevalence of late gastrointestinal side effects. Methods and Materials: The UK Medical Research Council RT01 trial included 843 men with localized prostate cancer, who were treated for 6 months with neoadjuvant radiotherapy and were randomly assigned to either 64-Gy or 74-Gy CFRT. Toxicity was evaluated before CFRT and during long-term follow-up using Radiation Therapy Oncology Group (RTOG) grading, the Late Effects on Normal Tissue: Subjective, Objective, Management (LENT/SOM) scale, and Royal Marsden Hospital assessment scores. Patients regularly completed Functional Assessment of Cancer Therapy--Prostate (FACT-P) and University of California, Los Angeles, Prostate Cancer Index (UCLA-PCI) questionnaires. Results: In the dose-escalated group, the hazard ratio (HR) for rectal bleeding (LENT/SOM grade {>=}2) was 1.55 (95% CI, 1.17-2.04); for diarrhea (LENT/SOM grade {>=}2), the HR was 1.79 (95% CI, 1.10-2.94); and for proctitis (RTOG grade {>=}2), the HR was 1.64 (95% CI, 1.20-2.25). Compared to baseline scores, the prevalence of moderate and severe toxicities generally increased up to 3 years and than lessened. At 5 years, the cumulative incidence of patient-reported severe bowel problems was 6% vs. 8% (standard vs. escalated, respectively) and severe distress was 4% vs. 5%, respectively. Conclusions: There is a statistically significant increased risk of various adverse gastrointestinal events with dose-escalated CFRT. This remains at clinically acceptable levels, and overall prevalence ultimately decreases with duration of follow-up.

  20. Low-Speed Wind-Tunnel Tests of a Pilotless Aircraft Having Horizontal and Vertical Wings and Cruciform Tail

    DTIC Science & Technology

    1947-08-19

    otability and •••"nt.i’ol, to raonsure the oiloron effoctivenoaa, and to erllbrute tho r;.domo and tho Machmeter pitot -etr>tic orifices. It wus found...cnuo’jn largo errors in the static- pressure reading obtained by thn orlginr.? ol-.atio- tubo install:’.tion. A practical installation point on the...Machrceter pitot —ctatlc orifices c.-libration ere also presented. SYMBOLS C«C.R. P ~Pn H-P„ lift coefficient drag coo ."fie lent pitchlng-monent

  1. Lise Meitner and the beta-ray energy controversy: An historical perspective

    SciTech Connect

    Watkins, S.A.

    1983-06-01

    Much has been written about the early history of beta-ray research and the controversy it provoked. Many prominent physicists lent their talents to the solution of this puzzling problem. One of the foremost of these was Lise Meitner, conspicuous in the fray not only because of her creative experimental work, but also because of her attachment to a physical principle: the simplicity of nature. This article reviews the sequence of events as they preceded, coincided with, and followed her work on the subject.

  2. Lise Meitner and the beta-ray energy controversy: An historical perspective

    NASA Astrophysics Data System (ADS)

    Watkins, Sallie A.

    1983-06-01

    Much has been written about the early history of beta-ray research and the controversy it provoked. Many prominent physicists lent their talents to the solution of this puzzling problem. One of the foremost of these was Lise Meitner, conspicuous in the fray not only because of her creative experimental work, but also because of her attachment to a physical principle—the simplicity of nature. This article reviews the sequence of events as they preceded, coincided with, and followed her work on the subject.

  3. Triatoma jatai sp. nov. in the state of Tocantins, Brazil (Hemiptera: Reduviidae: Triatominae)

    PubMed Central

    Gonçalves, Teresa Cristina Monte; Teves-Neves, Simone Caldas; dos Santos-Mallet, Jacenir Reis; Carbajal-de-la-Fuente, Ana Laura; Lopes, Catarina Macedo

    2013-01-01

    Triatoma jatai sp. nov. is the first new species of triatomine to be described in the state of Tocantins, in the northern region of Brazil. It was caught on rock outcrops in the wild environment and, more recently, invading homes. While T. jatai sp. nov. is morphologically similar to Triatoma costalimai, it is distinguished by its general colouring, differences in the blotches on the connexivum, wing size in females and external structures of the male genitalia. The type series has been deposited in the Entomological Collection and Herman Lent Collection, Oswaldo Cruz Institute-Oswaldo Cruz Foundation, Rio de Janeiro, Brazil. PMID:23828010

  4. Improved Quantitative Debris Monitoring Capability

    DTIC Science & Technology

    1987-04-01

    voltage increase. A rate increase of the output was expected. The results were inconclusive because the oil contained 12 - r b a large amount of the 10...34ME%7A= - %ZT.ATQf This research was partially funded by the in-house 1 rdt )eri (lent research fund. 𔃻 CCSATI CODIES a S%.9jECT bE~,ohq. n~f...q.-bwrI This report describes the operation and performance evaluation results of a QDmi Mark TI prototype fine ferrous debris monitoring system

  5. David Packard’s Legacy on American Military Policy

    DTIC Science & Technology

    2015-03-25

    support and credibility it lent to the 1986 Goldwater-Nichols Act (GNA). GNA was not perfect , nor did if fix all the issues faced, then or now, by the...reforms that persist to this day and although not perfect , he was the right type of visionary leader injected into the system at AU/ACSC/SMITH, B/AY15...2014. Nemfakos, Charles, Irv Blickstein, Aine Seitz McCarthy, and Jerry M. Sollinger. The Perfect Storm. Research, Santa Monica: RAND Corporation

  6. Developing a Vision: Incorporating Ecosystem Services into Decision Making - Proceedings of a Workshop

    USGS Publications Warehouse

    Hogan, Dianna; Arthaud, Greg; Goodman, Iris; Pattison, Malka; Sayre, Roger G.; Shapiro, Carl; Van Horne, Bea

    2009-01-01

    The production, location, use, and value of ecosystem services have become an important factor in resource management. Decisions relating to resource conservation and restoration, as well as development, require an understanding of the services provided by natural systems and the response of these systems to natural and human-induced change. Increased demands for development and the resulting pressures on ecosystem services have lent urgency to the need for an improved understanding of the value of natural capital. However, resource management decisions are often made without considering the importance and value of services resulting from natural systems.

  7. Report of Operation FITZWILLIAM. Volume 1, Design of Operation and Summary of Results (REDACTED)

    DTIC Science & Technology

    1948-01-01

    reo~ Geiger cOUilters, and a second ’:’lith equipment for aea.suring the electrical current of the atmos!)here will a’U.g11lent the upper...minteDa.Dca an located at sue statian ’ CJ-374.) ’ ’ ’ .... oHliRWNG mas9IDIL ~ Tib~ (20Ull7.s.) 4tcir L. Bu 1er (43rd .1f1ns B;) 1’raoerlab...looat1on and amplitude ot · tbe ataospbem electric perturllltions. together vith the est:!mted awra.ge bac:tqp:ootmd. (5) "Fitzwmiam roriard• will

  8. Advanced Integrated Fuel/Combustion Systems

    DTIC Science & Technology

    2004-01-01

    Heat and Mass Transfer in Turbu- lent Pipe Channel Flow,’’ Int. Chem. Eng., 16, pp. 359–368. @26# L. P. Chin, V. R. Katta, and S. P. Heneghan...and heated transfer line for online analysis. A 0.32 mm ID GasPro GSC (Astec Separation Technologies, Inc.) ‘‘ Porous - Layer Open Tubular’’ (PLOT) column...species within a nondepleting fuel. Multi-dimensional effects are accounted for in Eqs. ~1! and ~2! by using convective heat and mass transfer

  9. Ethical dilemmas related to counseling clients living with HIV/AIDS.

    PubMed

    Garcia, J G; Froehlich, R J; Cartwright, B; Letiecq, D; Forrester, L E; Mueller, R O

    1999-01-01

    This study tested an eight-factor model of client actions/decisions in terms of the extent to which professionals counseling persons with HIV/AIDS believed that those actions/decisions presented ethical dilemmas, and the frequency with which they encountered such actions. A confirmatory factor analysis lent initial support for the hypothetical eight-factor ethical-dilemma model for the ratings regarding the extent to which the participants believed those items constituted ethical dilemmas. Similar results were obtained for the frequency ratings, but in this case a second, competing model was equally plausible. Several significant predictors of participant ratings were found and are discussed.

  10. Military Geography of the Sino-Soviet Border.

    DTIC Science & Technology

    1981-07-31

    Junggar Basin itself is a triangular wedge of mostly steppe land lying between the Tian Shan and the Altay ( Altai ) mountains to the north along the...Impe’rilI Soviet control of all rrIor east kit t he IUri I Mountains .) Al though of less immediate conciern, Rirso;isir strateistu; datinog from...determined by the huge salt lent represe’nted by Mongolia , a Soviet ally. To thle West, on tile Chinesew side are the X1in j ang-Uygpr (Sinkiang-Uighur) and

  11. L'astronomie dans le monde

    NASA Astrophysics Data System (ADS)

    Manfroid, J.

    2002-09-01

    Jeunes étoiles et vieilles galaxies; Chiens de Chasse; Des images en partie belges; Détection chimique de planètes?; Amas cannibale; Le pulsar œil de bœuf; Supernova 2002 DJ; Centaurus A; Et de cent; Près du trou noir; Un cratère sous la Merdu Nord; Des astéroï des frôlent la Terre; Photons fatigués; Taches solaires; Un grand lac martien; Les naines brunes en infrarouge; Bourrelet équatorial; Fusion de trous noirs; Le hamburger de Gomez; Matière sombre; Non aux étoiles à quarks

  12. [Mothers, children, and the policies of Chile's Servicio Nacional de Salud (1952-1964)].

    PubMed

    Zárate Campos, María Soledad; Godoy Catalán, Lorena

    2011-12-01

    This description and exploration of the early years of Servicio Nacional de Salud, founded in 1952, analyzes the agency's progress and challenges, as well as the role of the Programa de Salud Materno-Infantil. The latter program lent continuity to a variety of sanitary protection policies for mothers and children dating to the 1920s, while also improving and expanding on existing policies and devising new ones within the framework of social medicine. The program recorded successes but also encountered limitations, which derived not only from agency-specific problems but also from the social and economic ills afflicting the country as a whole.

  13. Simulation of Streamflow Regulation Effects on the Water Quality of the Allegheny River,

    DTIC Science & Technology

    1983-02-01

    M:LE 7213 EN, F:’ EACH RIVER MILE 0. 93 LENT (MILES) 1.81 CZAuTATIDN INTERVAL. 1RX O1 4 FIRST DAY’ OF S "JLATIC44 PFIC : 152 ( I .- 9I 7 3 ) L.AST DAY OF...FORM4 1. REORT NMBER 2. GOVT ACCESSION No. 3 - RECIPIENT’S CATALOG NUMBER 4. TTLE andS15tiie)S. TYPE OF REPORT 6 PERIOD COVERED 6. PERFCRMING ORG. REPORT...I If. SUMMARY ill. DESCRIPTION OF THE STUDY AREA 3 Physical Setting 3 The Corps of Engineers Reservoir System and its Operation 7 IV. METHOD OF STUDY

  14. Operation Neptune, 6 June-8 July 1944 Normandy

    DTIC Science & Technology

    1944-07-01

    para6hute problems was map- ped out to begin with battalion drops and to culminate with a drop of three re- giments. Glider personnel trained with the...9th InfantrY Division passed through the bridgehead and attacked to..the west coast :of. tho. penis -sula. 325th _Glider Infantry Reogment The regiLent...IDUY R.iver southeast of ETIVI’J2 an.d. Wiest of MOITTESSY at 2809󈧓. orompnjy 3 erect - ed footbridges at NTIPBEiTVIELL and VI,:D󈧇>TT;I,’ tE for the

  15. Is Crohn's disease due to defective immunity?

    PubMed Central

    Korzenik, J R

    2007-01-01

    The understanding of the pathophysiology of Crohn's disease is currently undergoing a reassessment. The concept of this disease as a primary T cell disorder is being questioned, with a new emphasis on the role of innate immunity in initiating early events and in perpetuating the inflammatory state. Crohn's disease has been proposed instead to result from impaired innate immunity, encompassing the mucosal barrier and cellular elements including neutrophils and macrophages. Recent advances in genetics, functional studies on innate immunity and therapeutic trials on patients with Crohn's disease have lent support to this evolving hypothesis. PMID:17172582

  16. Diving Behaviour of Cuvier’s (Ziphius cavirostris) and Blainwille’s (Mesoplodon densirostris) Beaked Whales in Hawaii

    DTIC Science & Technology

    2006-01-01

    plongées les plus longues et les plus profondes et certaines espèces sont portées à s’échouer en groupe en réaction au sonar de forte intensité...remontée des plongées longues et profondes sont substantiellement plus lents que les taux de descente, alors que, pour les plongées plus courtes, il n’y...13 June 2006. Published on the NRC Research Press Web site at http://cjz.nrc.ca on 15 September 2006. R.W. Baird1 and G.S. Schorr. Cascadia Research

  17. Instrumentation for Surface Flux Measurements

    DTIC Science & Technology

    2012-05-10

    National Park , she used the sonic and a Li-Cor C02-H20 analyzer at a height of 3 m to measure the vertical turbulent flux of C02 downwind of...SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) U. S. Army Research Office P.O. Box 12211 Research Triangle Park , NC 27709-2211 3. REPORT TYPE...and subgrid-scale array measurements In summer 2000 we lent 7 of the CSAT3 sonics to the National Center for Atmo- spheric Research (NCAR) for use in

  18. Installation Restoration Program. Final Report Phase II, Stage 1 - Problem Confirmation Study, Norton Air Force Base, San Bernardino, California. Volume 2. Appendices.

    DTIC Science & Technology

    1985-07-01

    2, meets these activated carbon (Filtrasorb-300 or flask. criteria, equivalent (Calgon Corp.)). .a e6.5.2.2 Gases-To prepare standarcs U. 5.2.4 The...through a carbon filter bed contsining the stock standard. Commercially syringe with a 0.006 inch ID needle about 1 lb. of activated carbon ...500 g of activated carbon (Calgon Corp., Filtrasorb-300, or equivalent). 5.1.2 A water purification system (Millipore Super-Q or equiva- lent) may be

  19. Where are the women in women's sports? Predictors of female athletes' interest in a coaching career.

    PubMed

    Moran-Miller, Kelli; Flores, Lisa Y

    2011-03-01

    In this study, we used social cognitive career theory (Lent, Brown, & Hackett, 1994) to examine the development of female athletes' career interest in coaching and, specifically, the impact of contextual factors (female coaching role models, working hours, and perceived discrimination) on coaching self-efficacy and outcome expectations. Participants were 205 predominantly White, heterosexual female student athletes. A path analysis indicated that role models and working hours predicted coaching self-efficacy, which predicted coaching outcome expectations. Additionally, coaching self-efficacy, coaching outcome expectations, and contextual factors predicted coaching interest. Practical implications are discussed as well as suggestions for further research in this relatively unexplored area.

  20. Direct Effects of Phosphate on Vascular Cell Function

    PubMed Central

    Lau, Wei Ling; Pai, Ashwini; Moe, Sharon M.; Giachelli, Cecilia M.

    2011-01-01

    Elevated serum phosphate has clinically been associated with vascular stiffness and cardiovascular mortality. Mechanistic studies over the past decade looking at phosphate’s local effects on the vessel wall have lent insight into various pathways that culminate in vascular calcification.Smooth muscle cell phenotype change and apoptosis play prominent roles. The sodium-phosphate cotransporter PiT-1 is required for the osteochondrogenic differentiation of smooth muscle cellsin vitro. Less is known about phosphate-driven valve interstitial cell calcification and elastin degradation.In this paper, we review the current knowledge about phosphate-induced changes in the vascular wall. PMID:21406295

  1. Laser cooling of a trapped two-component Fermi gas

    SciTech Connect

    Idziaszek, Z.; Santos, L.; Lewenstein, M.; Baranov, M.

    2003-04-01

    We study the collective Raman cooling of a trapped two-component Fermi gas using quantum master equation in the festina lente regime, where the heating due to photon reabsorption can be neglected. The Monte Carlo simulations show that three-dimensional temperatures of the order of 0.008T{sub F} can be achieved. We analyze the heating related to background losses, and show that our laser-cooling scheme can maintain the temperature of the gas without significant additional losses.

  2. Access Control for Home Data Sharing: Attitudes, Needs and Practices

    DTIC Science & Technology

    2009-10-01

    roommates or F for families), household number within that type and member letter. For example, participant R2A belongs to the second roommate household (R2...moment.” R2A , a law student, once lent her computer to her adolescent sister, who inserted random words into a class assignment. R2A turned in the altered...bury sensitive files in layers of directories. According to R2A , “If you name something ‘8F2R349,’ who’s going to look at that?” C2B said, “[My

  3. Reconnaissance-Level Assessment of Water Quality Near Flandreau, South Dakota

    DTIC Science & Technology

    2002-01-01

    product .50 Anthraquinone No 84-65-1 Manufacturing dye/ textiles , seed treatment, bird repel - lent .50 Benzo[a]pyrene Yes 50-32-8 Regulated PAH, used in...drainage .50 N,N′ -diethyl-meta-toluamide (DEET) No 134-62-3 Insecticide, urban uses, mosquito repellent .50 Naphthalene No 91-20-3 Fumigant, moth...R.J., and Brunett, J.O., 1985, Overview of the occurrence of nitrate in ground water of the United States, in National Water Summary 1984—Hydro

  4. U.S. POSTDOCS: Report Urges Better Treatment, Status.

    PubMed

    Mervis, J

    2000-09-15

    For years, U.S. postdocs have been complaining about paltry salaries, lack of benefits, and lowly status. This week, a committee of the National Academies of Sciences and Engineering and the Institute of Medicine validated many of their complaints and lent its considerable weight to efforts to provide greater institutional support for postdocs. At the same time, however, the panel sidestepped two burning issues by explicitly declining to recommend a boost in postdoc salaries or take a position on whether to curtail the size of the postdoc workforce, which has more than doubled in the past 20 years to an estimated 52,000.

  5. Pressure Drop in Tank and Float Vent Tubes on Diving Airplane

    DTIC Science & Technology

    1939-01-01

    diameters of 13/32 and 21/32 inch were lent on a 6-inch radius and the 37/32-inch tube was tent on a 9-inch radius. Friction measurements with the 13/32...tube oponod into a velum .-; co.i;al to that of tho vontod tank or float on the diving airplane-. Tho flight tost was nado with a 4.55-cubic-foot tank...would on a diving airplane. Included in figure 6 aye the curves for the varyir.g-temveri.ture and. tho core tent - temperature conditions ooaputed

  6. Differentiation between Triatoma arthurneivai and Triatoma wygodzinskyi (Hemiptera: Reduviidae: Triatominae) using cytotaxonomy.

    PubMed

    Alevi, K C C; Imperador, C H L; Moreira, F F F; Jurberg, J; Azeredo-Oliveira, M T V

    2016-06-20

    Using classic morphometric techniques to examine the head and thorax of Triatoma specimens, researchers identified a possible taxonomic problem involving T. arthurneivai (Lent & Martins) and T. wygodzinskyi (Lent). A recent geometric morphometric study indicated that the insects captured outside the Serra do Cipó region, State of Minas Gerais, Brazil, were T. wygodzinskyi. The misidentification of T. arthurneivai as T. wygodzinskyi could result in several problems associated with entoepidemiological lifting, the biological characterization of the species, and phylogenetic reconstruction. For the first time, we describe the use of cytogenetic analysis as a tool for differentiation between T. arthurneivai and T. wygodzinskyi. The results indicated that both species had the same number of chromosomes 2n = 22 (20A + XY). However, analyses of spermatocytes during early prophase indicated that it was possible to differentiate T. arthurneivai and T. wygodzinskyi, because only T. arthurneivai exhibited heteropycnotic blocks distributed in the chromatin. Therefore, we highlight the analysis of spermatocytes as a taxonomic tool for the characterization of T. arthurneivai and T. wygodzinskyi, and suggest that the technique can be used for entoepidemiological lifting in vector control programs. Thus, the results presented here, in conjunction with morphometric analyses, are of utmost taxonomic and epidemiological importance for the identification of T. arthurneivai and T. wygodzinskyi specimens.

  7. Molecular quantum-dot cellular automata--from molecular structure to circuit dynamics

    NASA Astrophysics Data System (ADS)

    Lu, Yuhui; Lent, Craig

    2008-03-01

    Quantum-dot cellular automata (QCA) [1] provides a transistor-less paradigm for molecular electronics. In the QCA approach, binary information is stored in the charge configuration of single cells, and transferred via Coulomb coupling between neighboring cells. Single-molecule QCA cells can be realized by using as quantum dots the localized states of mixed-valence complexes. Several candidate QCA molecules have been synthesized and shown to have the required field-induced switching properties [2]. We report progress towards a hierarchic dynamic theory of QCA circuits. We use ab initio techniques to calculate the relevant molecular electronic structure, and extract parameters for a simpler Hamiltonian to describe switching behavior. We then apply a coherence vector formalism to model interaction with the thermal environment and generate a circuit-dynamic description. [1] C. S. Lent, P. D. Tougaw, W. Porod, and G. H. Bernstein, Nanotechnology, vol. 4, pp. 49, 1993. [2] H. Qi, S. Sharma, Z. Li, G. L. Snider, A. O. Orlov, C. S. Lent, and T. P. Fehlner, J.Am.Chem.Soc., vol. 125, pp. 15250, 2003.

  8. Hyperbaric Oxygen Therapy for Radiation-Induced Cystitis and Proctitis

    SciTech Connect

    Oliai, Caspian; Fisher, Brandon; Jani, Ashish; Wong, Michael; Poli, Jaganmohan; Brady, Luther W.; Komarnicky, Lydia T.

    2012-11-01

    Purpose: To provide a retrospective analysis of the efficacy of hyperbaric oxygen therapy (HBOT) for treating hemorrhagic cystitis (HC) and proctitis secondary to pelvic- and prostate-only radiotherapy. Methods and Materials: Nineteen patients were treated with HBOT for radiation-induced HC and proctitis. The median age at treatment was 66 years (range, 15-84 years). The range of external-beam radiation delivered was 50.0-75.6 Gy. Bleeding must have been refractory to other therapies. Patients received 100% oxygen at 2.0 atmospheres absolute pressure for 90-120 min per treatment in a monoplace chamber. Symptoms were retrospectively scored according to the Late Effects of Normal Tissues-Subjective, Objective, Management, Analytic (LENT-SOMA) scale to evaluate short-term efficacy. Recurrence of hematuria/hematochezia was used to assess long-term efficacy. Results: Four of the 19 patients were lost to follow-up. Fifteen patients were evaluated and received a mean of 29.8 dives: 11 developed HC and 4 proctitis. All patients experienced a reduction in their LENT-SOMA score. After completion of HBOT, the mean LENT-SOMA score was reduced from 0.78 to 0.20 in patients with HC and from 0.66 to 0.26 in patients with proctitis. Median follow-up was 39 months (range, 7-70 months). No cases of hematuria were refractory to HBOT. Complete resolution of hematuria was seen in 81% (n = 9) and partial response in 18% (n = 2). Recurrence of hematuria occurred in 36% (n = 4) after a median of 10 months. Complete resolution of hematochezia was seen in 50% (n = 2), partial response in 25% (n = 1), and refractory bleeding in 25% (n = 1). Conclusions: Hyperbaric oxygen therapy is appropriate for radiation-induced HC once less time-consuming therapies have failed to resolve the bleeding. In these conditions, HBOT is efficacious in the short and long term, with minimal side effects.

  9. Laser-induced fluorescence of space-exposed polyurethane

    NASA Technical Reports Server (NTRS)

    Hill, Ralph H., Jr.

    1993-01-01

    The object of this work was to utilize laser-induced fluorescence technique to characterize several samples of space-exposed polyurethane. These samples were flown on the Long Duration Exposure Facility (LDEF), which was in a shuttle-like orbit for nearly 6 years. Because of our present work to develop laser-induced-fluorescence inspection techniques for polymers, space-exposed samples and controls were lent to us for evaluation. These samples had been attached to the outer surface of LDEF; therefore, they were subjected to thermal cycling, solar ultraviolet radiation, vacuum, and atomic oxygen. It is well documented that atomic oxygen and ultraviolet exposure have detrimental effects on many polymers. This was a unique opportunity to make measurements on material that had been naturally degraded by an unusual environment. During our past work, data have come from artificially degraded samples and generally have demonstrated a correlation between laser-induced fluorescence and tensile strength or elasticity.

  10. Current Trends in Plague Research: From Genomics to Virulence

    PubMed Central

    Huang, Xiao-Zhe; Nikolich, Mikeljon P.; Lindler, Luther E.

    2006-01-01

    Yersinia pestis is the causative agent of plague, which diverged from Yersinia pseudotuberculosis within the past 20,000 years.Although these two species share a high degree of homology at the DNA level (>90%), they differ radically in their pathogenicity and transmission. In this review, we briefly outline the known virulence factors that differentiate these two species and emphasize genetic studies that have been conducted comparing Y. pestis and Y. pseudotuberculosis.These comparisons have led to a better understanding of the genetic contributions to the differences in the virulence and pathogenicity between these two organisms and have generated information that can be applied in future diagnostic and vaccine development. Comparison of the genetic differences between Y. pestis and Y. pseudotuberculosis has also lent insight into the emergence of acute pathogens from organisms causing milder diseases. PMID:16988099

  11. Productivity --- 8 for 8. [Labor Relations at Gulf Oil

    SciTech Connect

    Breaux, M.P.

    1983-03-01

    According to the author, a spokesman for Gulf Oil Corporation, the petroleum industry in the United States has reason to be proud of its record in labor relations, in labor negotiations, and in the success of its bargaining. For many years, this industry found itself alone in advocating noncompliance with COLAs and not participating in fully paid medical plans and other labor programs other industries felt it necessary to adopt and underwrite. This staunch resistance lent the petroleum industry, over the years, the reputation of an industrial dinosaur, but this has lately changed as industry at large, especially during an economic recession, has seen the wisdom behind the motives of the petroleum industry. The author goes on to state that Gulf's employees are well paid and that the last contract, stipulating a 9 percent and 7 percent increase over the next two years, was a bilaterally fair settlement.

  12. Nematode Parasites of Teiid Lizards from the Brazilian Amazon Rainforest.

    PubMed

    Macedo, Lilian Cristina; Gardner, Scott L; Melo, Francisco Tiago Vasconcelos; Giese, Elane Guerreiro; Dos Santos, Jeannie Nascimento

    2016-11-30

    This study presents the helminth composition and parameters of infection by several species of nematodes in teiid lizards, Ameiva a. ameiva (Linnaeus, 1758), Cnemidophorus cryptus Cole & Dessauer, 1993, and Kentropyx calcarata Spix, 1825 from the Brazilian Amazonian Rainforest. The lizard populations we studied were parasitized by six species of Nemata, including: Spinicauda spinicauda (Olfers, 1919), Parapharyngodon alvarengai Freitas, 1957, Physaloptera sp. (adults), Physaloptera sp. (larvae), Piratuba digiticauda Lent and Freitas, 1941, and Anisakidae (larvae). The overall prevalence was 66.17% and the mean intensity of infection was 19.40 ± 25.48. The association between the body-length of lizards and abundance and richness of parasitic nematodes was statistically significant only in Ameiva a. ameiva. A new host record is reported here with one specimen of the family Anasakidae in Ameiva a. ameiva. Both S. spinicauda and Physaloptera sp. represent new records from C. cryptus.

  13. Personalized nutrition and obesity.

    PubMed

    Qi, Lu

    2014-08-01

    The past few decades have witnessed a rapid rise in nutrition-related disorders such as obesity in the United States and over the world. Traditional nutrition research has associated various foods and nutrients with obesity. Recent advances in genomics have led to identification of the genetic variants determining body weight and related dietary factors such as intakes of energy and macronutrients. In addition, compelling evidence has lent support to interactions between genetic variations and dietary factors in relation to obesity and weight change. Moreover, recently emerging data from other 'omics' studies such as epigenomics and metabolomics suggest that more complex interplays between the global features of human body and dietary factors may exist at multiple tiers in affecting individuals' susceptibility to obesity; and a concept of 'personalized nutrition' has been proposed to integrate this novel knowledge with traditional nutrition research, with the hope ultimately to endorse person-centric diet intervention to mitigate obesity and related disorders.

  14. Chinese College Test Takers' Individual Differences and Reading Test Performance: A Structural Equation Modeling Approach.

    PubMed

    Zhang, Limei

    2016-06-01

    This study reports on the relationships between test takers' individual differences and their performance on a reading comprehension test. A total of 518 Chinese college students (252 women and 256 men; M age = 19.26 year, SD = 0.98) answered a questionnaire and sit for a reading comprehension test. The study found that test takers' L2 language proficiency was closely linked to their test performance. Test takers' employment of strategies was significantly and positively associated with their performance on the test. Test takers' motivation was found to be significantly associated with reading test performance. Test anxiety was negatively related to their use of reading strategies and test performance. The results of the study lent support to the threshold hypothesis of language proficiency. The implications for classroom teaching were provided. © The Author(s) 2016.

  15. Use of flow cytometry for high-throughput cell population estimates in brain tissue

    PubMed Central

    Young, Nicole A.; Flaherty, David K.; Airey, David C.; Varlan, Peter; Aworunse, Feyi; Kaas, Jon H.; Collins, Christine E.

    2012-01-01

    The large size of primate brains is an impediment to obtaining high-resolution cell number maps of the cortex in humans and non-human primates. We present a rapid, flow cytometry-based cell counting method that can be used to estimate cell numbers from homogenized brain tissue samples comprising the entire cortical sheet. The new method, called the flow fractionator, is based on the isotropic fractionator (IF) method (Herculano-Houzel and Lent, 2005), but substitutes flow cytometry analysis for manual, microscope analysis using a Neubauer counting chamber. We show that our flow cytometry-based method for total cell estimation in homogenized brain tissue provides comparable data to that obtained using a counting chamber on a microscope. The advantages of the flow fractionator over existing methods are improved precision of cell number estimates and improved speed of analysis. PMID:22798947

  16. Host-parasite relationships of Zootoca vivipara (Sauria: Lacertidae) in the Pyrenees (North Spain).

    PubMed

    Sanchis, V; Roig, J M; Carretero, M A; Roca, V; Llorente, G A

    2000-01-01

    The helminths infesting the common lizard, Zootoca vivipara (Jacquin, 1787), were studied with special attention to the relations between the number of nematodes, Oswaldocruzia filiformis (Goeze, 1782), and the size, sex and age class of the host. The possible seasonality of the parasite intensity and the relationship with the feeding habits of the host were also tested. Helminth infracommunities of Z. vivipara were depauperate with lizards harbouring only two species, the trematode Plagiorchis molini (Lent et Freitas, 1940) and the nematode O. filiformis. A positive correlation between host size and the number of O. filiformis was found for female Z. vivipara. However, no correlation was detected between intensity and sex or age class. The feeding habits of Z. vivipara, the isolation of the population studied and the low level of interaction with other reptilian or amphibian species are suggested as the causes of the depauperate helminth infracommunities found in this lacertid lizard.

  17. Network characteristics, perceived social support, and psychological adjustment in mothers of children with autism spectrum disorder.

    PubMed

    Benson, Paul R

    2012-12-01

    This study examined the characteristics of the support networks of 106 mothers of children with ASD and their relationship to perceived social support, depressed mood, and subjective well-being. Using structural equation modeling, two competing sets of hypotheses were assessed: (1) that network characteristics would impact psychological adjustment directly, and (2) that network effects on adjustment would be indirect, mediated by perceived social support. Results primarily lent support to the latter hypotheses, with measures of network structure (network size) and function (proportion of network members providing emotional support) predicting increased levels of perceived social support which, in turn, predicted decreased depressed mood and increased well-being. Results also indicated that increased interpersonal strain in the maternal network was directly and indirectly associated with increased maternal depression, while being indirectly linked to reduced well-being. Study limitations and implications are discussed.

  18. Optimization of Orchestral Layouts Based on Instrument Directivity Patterns

    NASA Astrophysics Data System (ADS)

    Stroud, Nathan Paul

    The experience of hearing an exceptional symphony orchestra perform in an excel- lent concert hall can be profound and moving, causing a level of excitement not often reached for listeners. Romantic period style orchestral music, recognized for validating the use of intense emotion for aesthetic pleasure, was the last significant development in the history of the orchestra. In an age where orchestral popularity is waning, the possibil- ity of evolving the orchestral sound in our modern era exists through the combination of our current understanding of instrument directivity patterns and their interaction with architectural acoustics. With the aid of wave field synthesis (WFS), newly proposed variations on orchestral layouts are tested virtually using a 64-channel WFS array. Each layout is objectively and subjectively compared for determination of which layout could optimize the sound of the orchestra and revitalize the excitement of the performance.

  19. The advent of printing as an obstacle to the development of rational medicine.

    PubMed

    Ring, M E

    1972-07-01

    At the time that printing came onto the scene in western Europe in the mid-1400s, the medical community was struggling in the depths of superstition, and little rational medicine was being practiced. With this new invention, a flood of ancient, outmoded texts was released upon the public, and eager readers frequently were unaware that books they were being sold as new works were actually in some cases a thousand years old. Added to this was the fact that the appearance in print of this irrational material lent credibility and authoritativeness to unscientific writings. Thus, in contrast to many other fields which were immeasurably helped by the advent of the printed book, rational medicine was in fact held back and prevented from developing for at least a full century. It was not until the Renaissance was well under way that important original contributions by such towering figures as Vesalius supplanted these worthless repetitions of ancient superstitions.

  20. Does powerlessness explain the relationship between intimate partner violence and depression?

    PubMed

    Filson, Jennifer; Ulloa, Emilio; Runfola, Cristin; Hokoda, Audrey

    2010-03-01

    The current study aimed to test whether relationship power could act as a mediator of the relationship between intimate partner violence and depression. The proposed mediation model was based on the theory of gender and power and on previous research of intimate partner violence and depression. Survey results from a sample of 327 single undergraduate women lent support to the hypothesis stating that relationship power accounts for some of the association between intimate partner violence and depression. Results revealed that women who felt powerless had higher rates of intimate violence victimization and higher levels of depression; a mediation analysis revealed that sexual relationship power mediated the relationship between intimate partner violence and depression. Future interventions targeting the prevention of intimate partner violence among young women may want to utilize an empowerment approach to decrease their likelihood of experiencing dating violence victimization and their subsequent risk for depression.

  1. Molecular Spintronics: Theory of Spin-Dependent Electron Transport Between Iron Nano-Contacts Bridged by Organic Molecules and Fe Atomic Chains*

    NASA Astrophysics Data System (ADS)

    Dalgleish, Hugh

    2005-03-01

    Recent experiments [1] have lent support to theoretical predictions [2] that organic molecules connecting nickel nano-contacts may exhibit magneto-resistance and spin-valve effects. Here we present predictions of spintronic phenomena in another class of ferromagnetic nano-systems: Fe nano-contacts bridged by single conducting or insulating molecules or chains of Fe atoms. Models are constructed based on semi-empirical considerations, the known electronic structure of bulk Fe and ab initio density functional calculations. Using Lippmann-Schwinger and Green's function techniques, and Landauer theory, significant magneto-resistance is predicted in these systems. Under appropriate conditions, novel device characteristics such as negative magneto-resistance are also predicted to emerge. * Supported by NSERC and the Canadian Institute for Advanced Research. 1 J. R. Petta et al., Phys. Rev. Lett. 93, 136601 (2004). 2 E. G. Emberly and G. Kirczenow, Chem. Phys. 281, 311 (2002); R. Pati, et al., Phys. Rev. B 68, 100407 (2003).

  2. Petrifying the nation: paleontology collections in Brazil, 1836-1844.

    PubMed

    Martinez, Paulo Henrique

    2012-12-01

    The formation and study of natural history and paleontology collections was part of the installation of political order under the Empire of Brazil, as well as the establishment of a scientific program. The symbiosis between science and the nation was actively promoted by Peter W. Lund, pioneer of paleontology studies in the country. The collections and writings produced by the naturalist lent support to the visualization of the past and the writing of history in Brazilian and European scientific and cultural institutions and museums. The disputes over the political order under the Regencies and the Majority were closely accompanied by the study and explanation of the forms of life and the planet found in the past.

  3. The development and construct validation of a Spanish version of an Academic Self-Concept scale for middle school Hispanic students from families of low socioeconomic levels.

    PubMed

    Menjares, P C; Michael, W B; Rueda, R

    2000-05-01

    For a sample of 305 6th, 7th and 8th grade students, of whom 95% was from economically disadvantaged Hispanic families and for whom English was their second language, evidence was sought regarding the reliability and construct validity of scores on a Spanish version of an academic self-concept measure entitled Dimensions of Self-Concept (DOSC), comprising five subscales bearing the same names as those of the five hypothesized constructs that they were intended to operationalize: Level of Aspiration, Anxiety, Academic Interest and Satisfaction, Leadership and Initiative, and Identification versus Alienation. Reliability estimates varying between .72 and .80 were judged to be reasonably satisfactory. Results from oblique factor analysis lent empirical support for the hypothesized constructs of Anxiety, Leadership and Initiative, and Identification versus Alienation. Scores associated with the subscales of Level of Aspiration and Academic Interest and Satisfaction generated a factor interpreted as a fusion of the two constructs of Level of Aspiration and Academic Interest and Satisfaction.

  4. Media Use, Cognitive Performance, and Life Satisfaction of the Chinese Elderly.

    PubMed

    Sun, Shaojing; Zhang, Shuangyue; Fan, Xitao

    2016-10-01

    Media use and aging is an important interdisciplinary topic pertaining to communication, gerontology, and psychology, among others. Integrating research on media-induced recovery and life satisfaction, the present study examined media uses and effects in the context of health and aging. Specifically, data from a large random sample were analyzed to investigate the relationships between media use, cognitive performance, and life satisfaction among the Chinese elderly. Results, in general, lent support to the slightly modified structural model. Specifically, media-induced recovery outcomes can be categorized into proximate (e.g., cognitive performance), intermediate (e.g., health satisfaction), and distal levels (e.g., life satisfaction). Also, situational factors (e.g., disease history) had statistically significant effects on media-induced recovery outcomes. Theoretical and practical implications of the research findings were discussed, and future research directions were suggested.

  5. A phylogenetic view of the Out of Asia/Eurasia and Out of Africa hypotheses in the light of recent molecular and palaeontological finds.

    PubMed

    Árnason, Úlfur

    2017-09-05

    The substantiality of the Out of Africa hypothesis was addressed in the light of recent genomic analysis of extant humans (Homo sapiens sapiens, Hss) and progress in Neanderthal palaeontology. The examination lent no support to the commonly assumed Out of Africa scenario but favoured instead a Eurasian divergence between Neanderthals and Hss (the Askur/Embla hypothesis) and an Out of Asia/Eurasia hypothesis according to which all other parts of the world were colonized by Hss migrations from Asia. The examination suggested furthermore that the ancestors of extant KhoeSan and Mbuti composed the first Hss dispersal(s) into Africa and that the ancestors of Yoruba made up a later wave into the same continent. The conclusions constitute a change in paradigm for the study of human evolution. Copyright © 2017. Published by Elsevier B.V.

  6. AN AUTOPSIC ART: DRAWINGS OF 'DR GRANVILLE'S MUMMY' IN THE ROYAL SOCIETY ARCHIVES.

    PubMed

    Riggs, Christina

    2016-06-20

    In 1821 Augustus Bozzi Granville FRS unwrapped and dissected an ancient Egyptian mummy, presenting the results of his examination to the Royal Society in 1825. He commissioned artist Henry Perry to draw the process in stages; these drawings were subsequently engraved by James Basire for publication in Philosophical Transactions. This article presents the original drawings for the first time, allowing comparison with their engravings. Taken together with Granville's accounts of the unwrapping of the mummy, the drawings demonstrate the significant role of illustration and other visual practices in anatomical argumentation in the early nineteenth century, as well as the prestige that commissioned illustrations lent to the performance and dissemination of scientific expertise. Moreover, the drawings include one of the key visual tropes of race science--a skull in left-facing profile, mapped with a facial angle--and thus indicate the early incorporation of Egyptian mummies into typologies of race.

  7. An autopsic art: drawings of ‘Dr Granville's mummy’ in the Royal Society archives

    PubMed Central

    Riggs, Christina

    2016-01-01

    In 1821 Augustus Bozzi Granville FRS unwrapped and dissected an ancient Egyptian mummy, presenting the results of his examination to the Royal Society in 1825. He commissioned artist Henry Perry to draw the process in stages; these drawings were subsequently engraved by James Basire for publication in Philosophical Transactions. This article presents the original drawings for the first time, allowing comparison with their engravings. Taken together with Granville's accounts of the unwrapping of the mummy, the drawings demonstrate the significant role of illustration and other visual practices in anatomical argumentation in the early nineteenth century, as well as the prestige that commissioned illustrations lent to the performance and dissemination of scientific expertise. Moreover, the drawings include one of the key visual tropes of race science—a skull in left-facing profile, mapped with a facial angle—and thus indicate the early incorporation of Egyptian mummies into typologies of race. PMID:27386713

  8. [Trust as a fundamental key for management in the service of people: Robert Spaemann's work].

    PubMed

    Marco Perles, Ginés Santiago

    2008-01-01

    In the present paper, we analyse the role of trust in the search for truthful health management in the service of people, bearing in mind the considerations of Robert Spaemann, Emeritus Professor of Ethics and Politics at the University of Munich. According to this author, trust is an intangible asset which helps the transmission of knowledge and the voluntary assumption of responsibility. In the first place, the transfer of knowledge, because the credibility of any professional involved in health management is threatened when such activity is carried out in a scenario in which managers may provide incentives for just the opposite of cooperative knowledge, so that transparency in the transmission of truth and "getting on" in one's career may appear in conflict. Secondly, the voluntary assumption of responsibilities, because the credibility of a health manager is lent weight when, in any contingency, he/she regularly puts the interests of patients before personal interests.

  9. Status of SOFCo SOFC technology development

    SciTech Connect

    Privette, R.; Perna, M.A.; Kneidel, K.

    1996-12-31

    SOFCo, a Babcock & Wilcox/Ceramatec Research & Development Limited Partnership, is a collaborative research and development venture to develop technologies related to planar, solid-oxide fuel cells (SOFCs). SOFCo has successfully demonstrated a kW-class, solid-oxide fuel cell module operating on pipeline natural gas. The SOFC system design integrates the air preheater and the fuel processor with the fuel cell stacks into a compact test unit; this is the platform for multi-kW modules. The cells, made of tape-cast zirconia electrolyte and conventional electrode materials, exhibit excel lent stability in single-cell tests approaching 40,000 hours of operation. Stack tests using 10-cm and 15-cm cells with ceramic interconnects also show good performance and stability in tests for many thousands of hours.

  10. De-coding the Neutral Hydrogen (21cm) Line Profiles of Disk galaxies

    NASA Astrophysics Data System (ADS)

    Moak, Sandy; Madore, Barry; Khatami, David

    2017-01-01

    Neutral hydrogen is the most abundant element in the interstellar medium, and it has long lent astronomers insight into galaxy structure, galactic interactions, and even dark matter prevalence. It is necessary to implement a detailed coding scheme that characterizes the 21-cm HI line profiles which exist in abundance throughout literature. We have utilized a new computer simulation program that exposes the internal architecture of a galaxy by way of mapping the one-dimensional line profile on to the three-dimensional parameters of a given galaxy. We have created a naming system to classify HI line profiles, which represents a kinematic description of the galaxy simply by considering its classification within the coding scheme.

  11. A shock-layer theory based on thirteen-moment equations and DSMC calculations of rarefied hypersonic flows

    NASA Technical Reports Server (NTRS)

    Cheng, H. K.; Wong, Eric Y.; Dogra, V. K.

    1991-01-01

    Grad's thirteen-moment equations are applied to the flow behind a bow shock under the formalism of a thin shock layer. Comparison of this version of the theory with Direct Simulation Monte Carlo calculations of flows about a flat plate at finite attack angle has lent support to the approach as a useful extension of the continuum model for studying translational nonequilibrium in the shock layer. This paper reassesses the physical basis and limitations of the development with additional calculations and comparisons. The streamline correlation principle, which allows transformation of the 13-moment based system to one based on the Navier-Stokes equations, is extended to a three-dimensional formulation. The development yields a strip theory for planar lifting surfaces at finite incidences. Examples reveal that the lift-to-drag ratio is little influenced by planform geometry and varies with altitudes according to a 'bridging function' determined by correlated two-dimensional calculations.

  12. Through-the-earth communication: Experiment results from Billie Mine and Mississippi Chemical Mine

    NASA Astrophysics Data System (ADS)

    Buettner, H. M.; Didwall, E. M.; Bukofzer, D. C.

    1988-06-01

    As part of the Lawrence Livermore National Laboratory (LLNL) effort to evaluate Through-the-Earth Communication (TEC) as an option for military communication systems, experiments were conducted involving transmission, reception, and performance monitoring of digital electromagnetic communication signals propagating through the earth. The two experiments reported on here not only demonstrated that TEC is useful for transmissions at digital rates above a few bits per second, but also provided data on performance parameters with which to evaluate TEC in various military applications. The most important aspect of these experiments is that the bit error rate (BER) is measured rather than just estimated from purely analytic developments. By measuring this important parameter, not only has more credibility been lent to the proof of concept goals of the experiment, but also a means for judging the effects of assumptions in BER theoretical models has been provided.

  13. Phylogenetic relationship among East Asian species of the Stegana genus group (Diptera, Drosophilidae).

    PubMed

    Li, Tong; Gao, Jian-jun; Lu, Jin-ming; Ji, Xing-lai; Chen, Hong-wei

    2013-01-01

    The phylogenetic relationship among 27 East Asian species of the Stegana genus group was reconstructed using DNA sequences of mitochondrial (COI and ND2) and nuclear (28S) genes. The results lent support to the current generic/subgeneric taxonomic classification in the genus group with the exceptions of the paraphyly of the genus Parastegana and the subgenus Oxyphortica in the genus Stegana. The ancestral areas and divergence times in the genus group were reconstructed/estimated, and accordingly, the biogeographical history of this important clade was discussed. It was proposed that, the evolution of the plant family Fagaceae, especially Quercus, may have played a certain role in facilitating the diversification of the Stegana genus group. Copyright © 2012 Elsevier Inc. All rights reserved.

  14. Schwannome bénin du nerf grand sciatique, à propos de 2 cas

    PubMed Central

    Chahbouni, Mohammed; Eloukili, Issam; Berrady, Mohamed Ali; Lamrani, Moulay Omar; Kharmaz, Mohamed; Ismail, Farid; Mahfoud, Mustapha; El Bardouni, Ahmed; Berrada, Mohamed Saleh; El Yaacoubi, Mouradh

    2014-01-01

    Les tumeurs primitives des nerfs périphériques représentent 1 à 2% des tumeurs des tissus mous. Les schwannomes sont en règle des tumeurs isolées de taille modérée et de croissance lente. Il convient de distinguer le schwannomes bénin et le neurofibrome des tumeurs malignes survenant généralement au cours d'une maladie de Recklinghausen. L'IRM permet d'orienter le diagnostic en mettant en évidence une tumeur de même signal que le tissu musculaire. Le traitement idéal de ces tumeurs consiste en une énucléation chirurgicale avec dissection soigneuse des faisceaux nerveux avoisinants. Nous rapportons deux cas d'un schwannome bénin développé aux dépens du nerf grand sciatique. PMID:25489357

  15. Longwall Guidance and Control Development

    NASA Technical Reports Server (NTRS)

    1982-01-01

    The longwall guidance and control (G&C) system was evaluated to determine which systems and subsystems lent themselves to automatic control in the mining of coal. The upper coal/shale interface was identified as the reference for a vertical G&C system, with two sensors (the natural backgound and the sensitized pick) being used to locate and track this boundary. In order to insure a relatively smooth recession surface (roof and floor of the excavated seam), a last and present cut measuring instrument (acoustic sensor) was used. Potentiometers were used to measure elevations of the shearer arms. The intergration of these components comprised the vertical control system (pitch control). Yaw and roll control were incorporated into a face alignment system which was designed to keep the coal face normal to its external boundaries. Numerous tests, in the laboratory and in the field, have confirmed the feasibility of automatic horizon control, as well as determining the face alignment.

  16. Toward Proof of Concept of a One Health Approach to Disease Prediction and Control

    PubMed Central

    Kock, Richard; Kachani, Malika; Kunkel, Rebekah; Thomas, Jason; Gilbert, Jeffrey; Wallace, Robert; Blackmore, Carina; Wong, David; Karesh, William; Natterson, Barbara; Dugas, Raymond; Rubin, Carol

    2013-01-01

    A One Health approach considers the role of changing environments with regard to infectious and chronic disease risks affecting humans and nonhuman animals. Recent disease emergence events have lent support to a One Health approach. In 2010, the Stone Mountain Working Group on One Health Proof of Concept assembled and evaluated the evidence regarding proof of concept of the One Health approach to disease prediction and control. Aspects examined included the feasibility of integrating human, animal, and environmental health and whether such integration could improve disease prediction and control efforts. They found evidence to support each of these concepts but also identified the need for greater incorporation of environmental and ecosystem factors into disease assessments and interventions. The findings of the Working Group argue for larger controlled studies to evaluate the comparative effectiveness of the One Health approach. PMID:24295136

  17. Effect of religious rules on time of conception in Romania from 1905 to 2001.

    PubMed

    Herteliu, Claudiu; Ileanu, Bogdan Vasile; Ausloos, Marcel; Rotundo, Giulia

    2015-09-01

    Does the interdiction of sexual intercourse during Nativity and Lent fasting periods have any effect on when babies are conceived in Romania, in the 20th century? Based on date of birth records from the 20th century, Lent had a greater effect than the Nativity fast on conception within the Eastern Orthodox (ORTHD) population. Seasonality of births (and therefore of conception) is affected by geographical factors (latitude, weather, day-length). Other demographic, economic and socio-cultural characteristics (education, ethnicity, religion) have been proved to have an influence on conception. The analyzed data consists of registered daily birth records for a long time series (35 429 points = 365 (days/year) × 97 years + 24 leap years), with 24 947 061 births in Romania over the period 1905-2001. The data were obtained from the 1992 and 2002 censuses. Based on the reported birth date of each person, the estimated date of conception is computed using a standard gestation period of 280 days. The population was grouped into two categories (ORTHD and Non-Orthodox (NORTHD)) based on religious affiliation. Data analysis is performed in the same manner for both groups. Preliminary data analyses regarding seasonal variations in conception are considered first. Econometric models are applied and tested. The dependent variable in these models is the calculated date of conception, while the independent variables are: (i) religious affiliation; (ii) dates of Nativity and Lent fasts (the latter varies slightly from year to year); (iii) rural versus urban residence; (iv) length of day-light; (v) non-working days and (vi) trend. The models are tested for validity using analysis of variance while the regression coefficients are tested by the Student t-test. All models are statistically valid (P < 0.01); all regression coefficients for the ORTHD group are valid (P < 0.01, except for rurality between 1990 and 2001, with P < 0.05). The data analysis indicates smaller standard error

  18. Academic satisfaction among Latino/a and White men and women engineering students.

    PubMed

    Flores, Lisa Y; Navarro, Rachel L; Lee, Hang Shim; Addae, Dorothy A; Gonzalez, Rebecca; Luna, Laura L; Jacquez, Ricardo; Cooper, Sonya; Mitchell, Martha

    2014-01-01

    The current study tests a model of academic satisfaction in engineering based on Lent, Brown, and Hackett's (1994, 2000) social cognitive career theory among a sample of 527 engineering majors attending a Hispanic serving institution. The findings indicated that (a) an alternative bidirectional model fit the data for the full sample; (b) all of the hypothesized relations were significant for the full sample, except the path from engineering interests to goals; (c) social cognitive career theory predictors accounted for a significant amount of variance in engineering goals (26.6%) and academic satisfaction (45.1%); and (d) the model parameters did not vary across men and women or across Latino/a and White engineering undergraduate students. Implications for research and practice are discussed in relation to persistence in engineering among women and Latinos/as. (c) 2014 APA, all rights reserved.

  19. Similarity of the patterns of sensilla on the antennae of Triatoma melanosoma and Triatoma infestans.

    PubMed

    Catalá, S; Torres, M

    2001-04-01

    The patterns of sensilla on the antennae of sylvatic Triatoma melanosoma Lent, Jurberg, Galvao and Carcavallo 1994 were compared with those of three samples of Triatoma infestans (Klug 1834) - one of domestic populations in Paraguay, Bolivia, Argentina and Chile, one of the sylvatic 'dark morph' from the Bolivian Chaco, and one from sylvatic sites in the Cochabamba region of Bolivia. The results of multivariate analysis indicated that, in terms of their antennal sensilla, the T. melanosoma and the 'dark morph' of T. infestans were more similar to the domestic T. infestans than to the sylvatic T. infestans from Cochabamba. As in previous molecular and genetic studies, there was no evidence to indicate that the bugs identified as T. melanosoma and those identified as T. infestans belonged to different species. The taxonomic position of T. melanosoma should therefore be reconsidered.

  20. Explicit and implicit horizons for simulated landing approaches.

    PubMed

    Lintern, G; Liu, Y T

    1991-08-01

    In a flight simulator experienced pilots flew landing approaches to a representation of an airport scene in which various sources of information had been distorted or removed. Reasonably accurate approaches could be made to a scene that contained only an aimpoint and a horizon. The addition of a runway outline did not enhance accuracy or stability, which lent credence to the hypothesis that the invariant angle between horizon and aimpoint can support glide slope control. Explicit distortion of this angle by simulation of up-sloping or down-sloping terrain beyond the runway had predictable effects on glide slope control. Implicit specification of a veridical horizon with texture lines parallel to the runway centerline weakened the effect of distortions in the explicit horizon. Thus both explicit and implicit specifications of the horizon contribute to perception of the glide slope angle. Implications of these results for the design of visual scenes for flight simulation are discussed.

  1. High-energy nearshore processes

    USGS Publications Warehouse

    1986-01-01

    The problem of shoreline erosion has become a matter of much interest in the recent press. To some extent this interest has been driven by the slow rise in sea level that has lent an air of inevitabilty to matters. However, the discussions certainly become more focused by the approach of a major storm or hurricane: for instance, the 1985 scare associated with Hurricane Gloria. In fact, it is these major events that dominate the episodic erosion history of an area, and so it is on the basis of knowledge of these events that decisions are made on the development and management of our shorelines. Unfortunately, both our understanding of the fundamental processes and the extent to which our knowledge is transmitted to coastal planners is less than we might hope.

  2. Origins and consequences of tripartite efficacy beliefs within elite athlete dyads.

    PubMed

    Jackson, Ben; Knapp, Peter; Beauchamp, Mark R

    2008-10-01

    Drawing from Lent and Lopez's (2002) "tripartite" model of relational efficacy, the overall purpose of this study was to examine antecedents and consequences of self-efficacy, other-efficacy, and relation-inferred self-efficacy (RISE) within six international-level athlete dyads. Semistructured interviews were conducted and data were content analyzed using deductive and inductive procedures. Sources of efficacy emerged in relation to perceptions regarding (i) oneself, (ii) one's partner, (iii) the dyad/relationship, and (iv) external factors. Results also revealed the emergence of a number of salient intrapersonal and interpersonal outcomes, incorporating cognitive, affective, as well as behavioral consequences. Implications for theory development and future research are considered, and applied propositions are discussed with regard to effective relationship management in elite sport.

  3. Pulmonary artery intimal sarcoma: a brief case series.

    PubMed

    Austin, Bethany A; Griffin, Brian P

    2008-08-01

    Primary pulmonary artery intimal sarcomas are often diagnosed only at the time of surgery or autopsy as a result of few specific findings both clinically and on imaging studies. We report two cases of this rare and lethal malignancy, both of which were initially thought to be manifestations of thromboembolic disease. In the case of one man, the diagnosis was delayed several months, at which point attempted surgical resection was not feasible. In the second case the echocardiographic and computed tomographic results generated further evaluation. This led to a more prompt diagnosis and treatment extending the patient's survival. In addition, we describe the echocardiographic findings that lent support to the need for surgical intervention and histologic diagnosis.

  4. From a pump handle to oral rehydration therapy: a model of translational research.

    PubMed

    Schultz, Stanley G

    2007-12-01

    Few afflictions have attracted as much attention and impacted on as many societal and biomedical areas as cholera. Dr. John Snow's studies launched the field of epidemiology, were early applications of medical cartography, and promoted the use of statistical methods in medicine. The finding that cholera was due to the ingestion of contaminated water lent to the demise of the prevalent "miasmatic theory of contagion," set the platform for the "germ theory of disease," and promoted the growth of public health concerns for water purification and sanitation. More recent attention to this disease led to the notion of "secretory diarrhea" and the translation of basic principles to the development of oral rehydration therapy and its "spin-offs" (Gatorade and Pedilyte).

  5. Sources of self-efficacy and coach/instructor behaviors underlying relation-inferred self-efficacy (RISE) in recreational youth sport.

    PubMed

    Saville, Paul D; Bray, Steven R; Martin Ginis, Kathleen A; Cairney, John; Marinoff-Shupe, Deborah; Pettit, Andrew

    2014-04-01

    Interpersonal feedback from coaches may be instrumental in the formation of children's self-efficacy to learn or perform sport skills. We report on two studies that explored perceived sources of self-efficacy and relation-inferred self-efficacy (RISE) in one-on-one interviews with sport camp participants (N = 61; ages 7-12) and focus groups with recreational league participants (N = 28; ages 8-12). Participants' responses indicated that prior experiences and socially constructed interactions contributed to the development of self-efficacy and RISE beliefs. Results support Bandura's (1997) theorizing that self-efficacy is developed through processing of experiential feedback as well as Lent and Lopez's (2002) tripartite theory proposing interpersonal feedback from influential others contributes to children's RISE and self-efficacy.

  6. [Prominence in the media, renown in the sciences: the construction of a paradigmatic feminist and a scientist at Rio de Janeiro's Museu Nacional].

    PubMed

    Lopes, Maria Margaret

    2008-06-01

    Bertha Lutz was one of the women of her generation who enjoyed indisputable political and scientific authority. She wrote much and even more was written about her, especially during her day. The newspaper chronicles by Lima Barreto, countless letters, scientific papers, and unpublished texts by Bertha herself that are surveyed in this article indicate how much her feminism--inseparable from other dimensions of her life--fostered her professional career. Her feminism earned her a carefully constructed renown and visibility that interlocked with her professional performance. Science lent her social prestige and guaranteed legitimacy for her causes. During a period when the scientific community itself was engaged in publicizing its own activities, Bertha's feminist prominence in the media helped her make a name in the sciences.

  7. A SYNCHRONIZED FIR/VUV LIGHT SOURCE AT JEFFERSON LAB

    SciTech Connect

    Stephen Benson, David Douglas, George Neil, Michelle D. Shinn, Gwyn Williams

    2012-07-01

    We describe a dual free-electron laser (FEL) configuration on the UV Demo FEL at Jefferson Lab that allows simultaneous lasing at FIR/THz and UV wavelengths. The FIR/THz source would be an FEL oscillator with a short wiggler providing nearly diffraction-limited pulses with pulse energy exceeding 50 microJoules. The FIR source would use the exhaust beam from a UVFEL. The coherent harmonics in the VUV from the UVFEL are out-coupled through a hole. The FIR source uses a shorter resonator with either hole or edge coupling to provide very high power FIR pulses. Simulations indicate excel-lent spectral brightness in the FIR region with over 100 W/cm-1 output.

  8. Sheet silicon cell/module technology

    NASA Technical Reports Server (NTRS)

    Morrison, A. D.

    1983-01-01

    The cost involved in the performance of the standard operations for the manufacture of silicon wafers is insignificant in the case of space photovoltaics applications. It is, however, a decisive factor with respect to terrestrial applications of silicon photovoltaic devices. In 1975, a program was, therefore, begun to develop low cost silicon solar arrays for terrestrial applications. The goal was silicon-based photovoltaic (PV) modules ready for installation at a selling price of $0.50/watt (1975 dollars). Sheet and ribbon silicon growth held out the promise of reduced cost through continuous operation, high material throughput, high material utilization efficiency, and a product whose shape lent itself to the assembly of high packing density modules. Attention is given to ribbon growth technologies, sheet technology generic problems, and ribbon cell and module technology status. It is concluded that the potential for crystalline ribbon silicon appears to be better today than ever before.

  9. Equations of Motion of a Ground Moving Target for a Multi-Channel Spaceborne SAR

    DTIC Science & Technology

    2009-03-01

    function of the receive phase center index p (= 1, 2, 3, etc.) along the antenna and the pulse (or slow) time t: Rp(t) = R0 +(p−1)D(Ψ−Φ0)+(Vtr − Vsr )(t...radial acceleration component. R0, Φ0, Vtr, Vta, and Atr are defined for time t0. Vsr depends onVs and Φ0 in a predictable way. Vs,Vg, andVe vary slowly...l’impulsion (lent) : Rp(t) = R0 +(p−1)D(Ψ−Φ0)+(Vtr − Vsr )(t − t0) + (p−1)D R0 (Vta −Vg)(t − t0)+ 1 2 ( V 2e −2VsVta R0 +Atr ) (t − t0) 2 Les équations

  10. Healing and the invention of metaphor: the effectiveness of symbols revisited.

    PubMed

    Kirmayer, L J

    1993-06-01

    In this essay, I argue that a theory of meaning adequate to account for the effectiveness of symbolic healing and psychotherapy requires some variant of the three concepts of myth, metaphor and archetype. Myth stands for the overarching narrative structures of the self produced and lent authority by cultural tradition. Archetype stands not for performed ideas or images, but for the bodily-given in meaning. Metaphor occupies an intermediate realm, linking narrative and bodily-given experience through imaginative constructions and enactments that allow movement in sensory-affective quality space. This pluralistic perspective itself constitutes a middle-ground between constructivist and realist approaches to meaning that can integrate causal and interpretive models of symbolic healing.

  11. James E. Webb, Technocracy, and the New Deal Roots of "Space Age Management".

    PubMed

    Needell, Allan A

    abstract James E. Webb, NASA's Administrator during the hectic years preparing to send American astronauts to the Moon, has come to represent the pinnacle of postwar American optimism and support for large-scale, technically complex national undertakings. Success in 1969 lent credence to Webb's faith in "space age management." By the 1980s such "technocratic optimism" had precipitously declined. Since 1985, with the publication of Walter A. McDougall's Pulitzer Prize winning. . . The Heavens and the Earth, the rise and decline of such optimism has often been framed in the context of Cold War ideology and competition. In this study, aspects of Webb's vision are traced back prior to World War II. It argues that Cold War emphasis, although certainly crucial for understanding the institutions and practices Webb directed, nevertheless tends to mask the full extent of the 1980s rejection of long standing attitudes toward planning, expertise, and rigorous scientific and technical knowledge.

  12. Applications of finite element and wave envelope element approximations to turbofan engine noise radiation including flight effects

    NASA Technical Reports Server (NTRS)

    Parrett, A. V.; Eversman, W.

    1984-01-01

    The problem of acoustic radiation from turbofan engine inlets in flow has not lent itself fully to analysis by numerical means because of the large domains and high frequencies involved. The current work has extended the use of finite elements and wave envelope elements, elements which simulate decay and wavelike behaviour in their interpolation functions, from the no-flow case in which they have been proven, to cases incorporating mean flow. By employing an irrotational mean flow assumption, the acoustics problem has been posed in an axisymmetric formulation in terms of acoustic velocity potential, thus minimizing computer solution storage requirements. The results obtained from the numerical procedures agree well with known analytical solutions, static experimental jet engines inflow data, and also with flight test results.

  13. A shock-layer theory based on thirteen-moment equations and DSMC calculations of rarefied hypersonic flows

    NASA Technical Reports Server (NTRS)

    Cheng, H. K.; Wong, Eric Y.; Dogra, V. K.

    1991-01-01

    Grad's thirteen-moment equations are applied to the flow behind a bow shock under the formalism of a thin shock layer. Comparison of this version of the theory with Direct Simulation Monte Carlo calculations of flows about a flat plate at finite attack angle has lent support to the approach as a useful extension of the continuum model for studying translational nonequilibrium in the shock layer. This paper reassesses the physical basis and limitations of the development with additional calculations and comparisons. The streamline correlation principle, which allows transformation of the 13-moment based system to one based on the Navier-Stokes equations, is extended to a three-dimensional formulation. The development yields a strip theory for planar lifting surfaces at finite incidences. Examples reveal that the lift-to-drag ratio is little influenced by planform geometry and varies with altitudes according to a 'bridging function' determined by correlated two-dimensional calculations.

  14. Processing-structure characterization of rheocast IN-100 superalloy

    NASA Technical Reports Server (NTRS)

    Cheng, Jung-Jen Allen; Apelian, Diran; Doherty, Roger D.

    1986-01-01

    The rheocasting solidification process was applied in the production of IN-100 nickel base superalloy, and the effects of processing variables, such as stirring speed, isothermal stirring time, and volume fraction solid during isothermal stirring, on the resultant rheocast structure were investigated. Ingots that were furnace cooled at the same rate but without stirring were compared with the rheocast ingots. Rheocasting yielded fine-grained structures, where the extent of microsegregation, the variation in macrostructure, and the solidification-induced porosity and ingot cracking were found to be reduced in comparison to the unstirred ingots. The grain size and nonuniformity were reduced by increasing the stirring speed, isothermal stirring time, or the volume fraction solid during stirring; decreased microsegregation was achieved by an increase in the volume fraction solid. The structures of grain boundaries lent support to the grain boundary mechanism proposed by Vogel et al. (1977) for rheocasting.

  15. Description and preliminary calibration results for the Langley hypersonic CF4 tunnel

    NASA Technical Reports Server (NTRS)

    Midden, R. E.; Miller, C. G.

    1978-01-01

    A detailed description of the hypersonic CF4 tunnel is presented along with discussion of the basic components, instrumentation, and operating procedure. Operational experience with the CF4 reclaimer and lead-bath heater is discussed. Comparison of measured and predicted shock detachment distance on a sphere and pressure distributions measured on a sharp leading-edge flat plate revealed the absence of significant flow nonuniformity and lent creditability to predicted free stream flow conditions. The economic operation of this facility centers about the CF4 reclaimer, which was designed to operate at an efficiency of 90 to 95 percent. A number of modifications were made to the reclaimer system to improve its performance, and presently, the system reclaims approximately 75 percent of the test gas. Even with current budgetary constraints, this efficiency permits the CF4 tunnel to be operated as a viable research wind tunnel.

  16. Sheet silicon cell/module technology

    NASA Technical Reports Server (NTRS)

    Morrison, A. D.

    1983-01-01

    The cost involved in the performance of the standard operations for the manufacture of silicon wafers is insignificant in the case of space photovoltaics applications. It is, however, a decisive factor with respect to terrestrial applications of silicon photovoltaic devices. In 1975, a program was, therefore, begun to develop low cost silicon solar arrays for terrestrial applications. The goal was silicon-based photovoltaic (PV) modules ready for installation at a selling price of $0.50/watt (1975 dollars). Sheet and ribbon silicon growth held out the promise of reduced cost through continuous operation, high material throughput, high material utilization efficiency, and a product whose shape lent itself to the assembly of high packing density modules. Attention is given to ribbon growth technologies, sheet technology generic problems, and ribbon cell and module technology status. It is concluded that the potential for crystalline ribbon silicon appears to be better today than ever before.

  17. The private sector role in financing mineral development

    SciTech Connect

    Baiz, C.F. III

    1982-01-01

    The role of the private sector, specifically commercial banks, is one of growing demand in financing mineral development as these projects become more capital intensive. From straightforward lending, to various forms of project financing that today borders on the exotic, to technical analytical capabilities on an in-house basis, the commercial bank has a definite role in the funding of metals and mineral development. However, from the outset, the single most important, yet most misunderstood, concept of a commercial bank's money must be pointed out. That is, the commercial bank is a source of debt capital, not equity capital. The commercial bank does not expect, nor does it get, the equity returns on its money lent. Therefore, neither will it accept the risks assumed by equity capital. These equity risks are correctly placed as the responsibility of the corporative shareholders.

  18. Applications of finite element and wave envelope element approximations to turbofan engine noise radiation including flight effects

    NASA Technical Reports Server (NTRS)

    Parrett, A. V.; Eversman, W.

    1984-01-01

    The problem of acoustic radiation from turbofan engine inlets in flow has not lent itself fully to analysis by numerical means because of the large domains and high frequencies involved. The current work has extended the use of finite elements and wave envelope elements, elements which simulate decay and wavelike behaviour in their interpolation functions, from the no-flow case in which they have been proven, to cases incorporating mean flow. By employing an irrotational mean flow assumption, the acoustics problem has been posed in an axisymmetric formulation in terms of acoustic velocity potential, thus minimizing computer solution storage requirements. The results obtained from the numerical procedures agree well with known analytical solutions, static experimental jet engines inflow data, and also with flight test results.

  19. From closed ranks to open doors: Elaine and John Cummings' mental health education experiment in 1950s Saskatchewan.

    PubMed

    Kendall, Kathleen

    2011-01-01

    During late 1951 and early 1952, married couple, social biologist Elaine Cumming and psychiatrist John Cumming, led a mental health education experiment in Indian Head, Saskatchewan. The study, which was intended to inform strategies toward deinstitutionalization, sought to determine if attitudes regarding mental illness could be changed through commonly used educational practices. It was shaped by the shared interests of powerful philanthropic, charitable, psychiatric, academic and governmental bodies to create healthier citizens and a stronger democratic nation through expert knowledge. However, in addition to the disappointing findings indicating that attitudes remained unchanged, the town appeared to close ranks against the research team. Nonetheless, the Cummings' later association with sociologists at Harvard University enabled them to interpret the results in a way that lent the study credibility and themselves legitimacy, thus opening the door to their careers as very successful researchers and policy-makers.

  20. A DISCUSSION ON UTILIZATION OF HEAT PIPE AND VAPOUR CHAMBER TECHNOLOGY AS A PRIMARY DEVICE FOR HEAT EXTRACTION FROM PHOTON ABSORBER SURFACES

    SciTech Connect

    Suthar, K. J.; Lurie, Alexander M.; Den Hartog, P.

    2016-01-01

    Heat pipes and vapour chambers work on heat exchange phenomena of two-phase flow and are widely used for in-dustrial and commercial applications. These devices offer very high effective thermal conductivities (5,000-200,000 W/m/K) and are adaptable to various sizes, shapes, and ori-entations. Although they have been found to be an excel-lent thermal management solution for laptops, satellites, and many things in-between, heat pipes and vapour cham-bers have yet to be adopted for use at particle accelerator facilities where they offer the possibility of more compact and more efficient means to remove heat from unwanted synchrotron radiation. As with all technologies, there are inherent limitations. Foremost, they are limited by practi-cality to serve as local heat transfer devices; heat transfer over long distances is likely best provided by other means. Heat pipes also introduce unique failure modes which must be considered.

  1. The Advent of Printing as an Obstacle to the Development of Rational Medicine

    PubMed Central

    Ring, Malvin E.

    1972-01-01

    At the time that printing came onto the scene in western Europe in the mid-1400s, the medical community was struggling in the depths of superstition, and little rational medicine was being practiced. With this new invention, a flood of ancient, outmoded texts was released upon the public, and eager readers frequently were unaware that books they were being sold as new works were actually in some cases a thousand years old. Added to this was the fact that the appearance in print of this irrational material lent credibility and authoritativeness to unscientific writings. Thus, in contrast to many other fields which were immeasurably helped by the advent of the printed book, rational medicine was in fact held back and prevented from developing for at least a full century. It was not until the Renaissance was well under way that important original contributions by such towering figures as Vesalius supplanted these worthless repetitions of ancient superstitions. PMID:4559907

  2. Role of momentum and velocity for radiating electrons

    NASA Astrophysics Data System (ADS)

    Capdessus, Rémi; Noble, Adam; McKenna, Paul; Jaroszynski, Dino A.

    2016-02-01

    Radiation reaction remains one of the most fascinating open questions in electrodynamics. The development of multi-petawatt laser facilities capable of reaching extreme intensities has lent this topic a new urgency, and it is now more important than ever to properly understand it. Two models of radiation reaction, due to Landau and Lifshitz and due to Sokolov, have gained prominence, but there has been little work exploring the relation between the two. We show that in the Sokolov theory, electromagnetic fields induce a Lorentz transformation between momentum and velocity, which eliminates some of the counterintuitive results of Landau-Lifshitz. In particular, the Lorentz boost in a constant electric field causes the particle to lose electrostatic potential energy more rapidly than it otherwise would, explaining the longstanding mystery of how an electron can radiate while experiencing no radiation reaction force. These ideas are illustrated in examples of relevance to astrophysics and laser-particle interactions, where radiation reaction effects are particularly prominent.

  3. Examining the career development of Mexican American middle school students: A test of social cognitive career theory

    NASA Astrophysics Data System (ADS)

    Navarro, Rachel Leah

    This study tested portions of Lent, Brown, and Hackett's (1994) Social Cognitive Career Theory (SCCT) in the domain of mathematics and science with a sample of Mexican American middle school students. Results supported a modified path model. This study's findings supported several SCCT propositions regarding the positive relationships among background contextual affordances, learning experiences, self-efficacy, outcome expectations, interests, and goals. However, findings suggested that the influence of person inputs (i.e., gender and generational status) and some background contextual affordances (i.e., acculturation level) on learning experiences may be not be direct; instead, an indirect effect via a relationship with other background contextual affordances (i.e., perceived social support and social class) was found. Furthermore, results supported direct effects of gender on self-efficacy and learning experiences on goal intentions---two relationships not posited in SCCT. Implications for future research and counseling with Mexican American adolescents are discussed.

  4. Project to design and develop an energy-related program: For public housing residents and renters: Volume 1, Final report

    SciTech Connect

    Not Available

    1988-05-01

    This demonstration project was undertaken as a result of an unsolicited proposal submitted by THE ASSIGNMENT GROUP (TAG) to the Office of Minority Economic Impact, Department of Energy (DOE). The problem to which the proposal responded was how to minimize the costs associated with public housing tenants in standard public housing as well as under homeownership transfers. A related problem was how to graduate the tenants to another level of responsibility and self-sufficiency through resident business developments and training in energy-related fields. The size and gravity of the problem necessitated a purpose or aim that had nationwide application, yet lent itself to a microscopic look. Consequently, the goal that emanated was the design and development of an energy-related demonstration program that educates public housing residents, facilitates indigenous business development where appropriate, and trains residents to provide needed services.

  5. The separation of lipoproteins from egg yolk and their effect on the motility and integrity of bovine spermatozoa.

    PubMed

    Foulkes, J A

    1977-03-01

    Lipoproteins were separated by centrifugation and column chromatography and included in citrate-based semen diluents. One lipoprotein fraction was particularly effective in preventing injury to bovine spermatozoa during dilution and freezing and thawing when assessed using motility and release of hyaluronidase as criteria of cell damage. Radioactive labelling of egg-yolk lipids demonstrated that egg-yolk components remained associated with spermatozoa even after extensive washing to remove diluent. The patterns of labelling of lipids extracte from the washed spermatozoa did not indicate that particular lipids became associated with spermatozoa. Increases in the specific radioactivity of lipid extracts from washed spermatozoa lent support to the contention that lipoproteins become firmly bound to the cells.

  6. Use of flow cytometry for high-throughput cell population estimates in brain tissue.

    PubMed

    Young, Nicole A; Flaherty, David K; Airey, David C; Varlan, Peter; Aworunse, Feyi; Kaas, Jon H; Collins, Christine E

    2012-01-01

    The large size of primate brains is an impediment to obtaining high-resolution cell number maps of the cortex in humans and non-human primates. We present a rapid, flow cytometry-based cell counting method that can be used to estimate cell numbers from homogenized brain tissue samples comprising the entire cortical sheet. The new method, called the flow fractionator, is based on the isotropic fractionator (IF) method (Herculano-Houzel and Lent, 2005), but substitutes flow cytometry analysis for manual, microscope analysis using a Neubauer counting chamber. We show that our flow cytometry-based method for total cell estimation in homogenized brain tissue provides comparable data to that obtained using a counting chamber on a microscope. The advantages of the flow fractionator over existing methods are improved precision of cell number estimates and improved speed of analysis.

  7. Modeling stochastic excitation of acoustic modes in stars: present status and perspectives

    NASA Astrophysics Data System (ADS)

    Samadi, R.; Belkacem, K.; Goupil, M.-J.; Ludwig, H.-G.; Dupret, M.-A.

    2008-12-01

    Solar-like oscillations have now been detected for more than ten years and their frequencies measured for a still growing number of stars with various characteristics (e.g. mass, chemical composition, evolutionary stage ...). Excitation of such oscillations is attributed to turbu- lent convection and takes place in the uppermost part of the convective envelope. Since the pioneering work of Goldreich & Keely (1977), more sophisticated theoretical models of stochastic excitation were developed, which differ from each other both by the way turbulent convection is modeled and by the assumed sources of excitation. We briefly review here the different underlying approximations and assumptions of those models. A second part shows that computed mode excitation rates crucially depend on the way time-correlations between eddies are described but also on the surface metal abundance of the star.

  8. Environmental induction of the fetal epigenome

    PubMed Central

    Odom, Lawrence N; Taylor, Hugh S

    2011-01-01

    The healthy adult is the result of successful interaction between the maternal environment and the developing fetal epigenome. The Barker hypothesis first suggested that in utero exposure to the maternal environment impacts adult health and disease. Since the origin of this theory, numerous studies have lent further support. Epigenomic alteration involves DNA methylation and histone modifications. Pregnancy, when the epigenome is typically actively programmed, is a vulnerable time, when exposures may have the most profound epigenetic effect. Recent advances have allowed an understanding of the extent and mechanism by which environmental exposures alter the epigenome of the fetus. Healthcare providers who treat and counsel reproductive-age women are in a unique position to protect against these epigenetic alterations and therefore prevent adverse impact on the developing fetus that may manifest throughout life. PMID:21297874

  9. New theoretical considerations in polymer rheology: Elastic breakdown of chain entanglement network

    NASA Astrophysics Data System (ADS)

    Wang, Shi-Qing; Ravindranath, Sham; Wang, Yangyang; Boukany, Pouyan

    2007-08-01

    Recent experimental evidence has motivated us to present a set of new theoretical considerations and to provide a rationale for interpreting the intriguing flow phenomena observed in entangled polymer solutions and melts [P. Tapadia and S. Q. Wang, Phys. Rev. Lett. 96, 016001 (2006); 96, 196001 (2006); S. Q. Wang et al., ibid. 97, 187801 (2006)]. Three forces have been recognized to play important roles in controlling the response of a strained entanglement network. During flow, an intermolecular locking force fiml arises and causes conformational deformation in each load-bearing strand between entanglements. The chain deformation builds up a retractive force fretract within each strand. Chain entanglement prevails in quiescence because a given chain prefers to stay interpenetrating into other chains within its pervaded volume so as to enjoy maximum conformational entropy. Since each strand of length lent has entropy equal to kBT, the disentanglement criterion is given by fretract>fent~kBT/lent in the case of interrupted deformation. This condition identifies fent as a cohesive force. Imbalance among these forces causes elastic breakdown of the entanglement network. For example, an entangled polymer yields during continuous deformation when the declining fiml cannot sustain the elevated fretract. This opposite trend of the two forces is at the core of the physics governing a ``cohesive'' breakdown at the yield point (i.e., the stress overshoot) in startup flow. Identifying the yield point as the point of force imbalance, we can also rationalize the recently observed striking scaling behavior associated with the yield point in continuous deformation of both shear and extension.

  10. Imagerie Resolue dans le Temps des Photons et Neutres Metastables Emis D'une Surface Par Stimulation Electronique

    NASA Astrophysics Data System (ADS)

    Leclerc, Gregoire

    L'appareil que nous presentons ici a ete mis au point pour permettre d'accumuler des images numeriques, resolues dans le temps, de la desorption par stimulation electronique (DSE) d'ions positifs et negatifs, de photons et de neutres metastables, tout en conservant des capacites de base de diffraction d'electrons lents (DEL) et de transmission d'electrons lents (TEL). Le spectrometre comporte un monochromateur d'electrons a secteur cylindrique de 127^ circ dont l'optique de sortie permet la focalisation du faisceau d'electrons sur une large gamme d'energies. Le detecteur consiste en un empilement de galettes de microcanaux et d'une anode resistive a encodage de division de charges. La reponse spatiale du detecteur a ete calibree et plusieurs causes de non-linearite ont ete localisees et corrigees. Des methodes de correction materielle et logicielle des distorsions spatiales sont presentees. La resolution temporelle des evenements est obtenue en pulsant le faisceau d'electrons, et de facon synchrone la detection, laquelle est couplee a un micro-ordinateur. La premiere partie de ce travail est consacree a la caracterisation du spectrometre et la presentation de nombreux parametres operationnels, obtenus soit au moment de la conception, soit experimentalement. Suit la presentation de donnees de DEL et de DSE pour le systeme Ar/Pt(111) en films minces a 15K. Les sequences temporelles d'images de metastables d'Ar desorbes ont revele la presence de plusieurs populations distinctes, ayant des distributions angulaires et distributions d'energie cinetique que nous avons pu separer. Les fonctions d'excitation de l'emission de photons et de la desorption de differentes composantes de metastables, ainsi que la dependance de ces signaux sur l'epaisseur des films d'Ar, sont aussi presentees et analysees. Les techniques que nous avons developpees ont permis de cerner les mecanismes en jeu pour la desorption et la luminescence.

  11. Predicting the STEM outcomes of academically qualified women: A longitudinal examination of social cognitive career theory

    NASA Astrophysics Data System (ADS)

    Wasson, Jillian Woodford

    There is a well-documented gender disparity in science, technology, engineering, and mathematics (STEM) fields, which has been the focus of research for several decades (i.e., Betz & Hackett, 1981; Ceci & Williams, 2009, 2010; Wang, Eccles, & Kenny, 2013). Questions as to why this is the case are not new; however, with the growing body of research, there seem to be more questions than answers. This study drew primarily from the vocational psychology literature, particularly Social Cognitive Career Theory, building on previous literature in this area by examining differences in career choices made over time by qualified women across different stages in the education-to-career pathway. The results of the present study indicate that among qualified women many of the SCCT personal and contextual variables are relevant to STEM career development. Moreover, findings from the present study support the hypothesis (Lent et al., 1994) that personal, environmental, and behavioral variables affect one another. An important aspect of the SCCT model is the acknowledgment that at any given point in time, certain variables will carry different weight (Lent et al., 1994). The current study provides further support for this and underscores the necessity of understanding and framing career development as a process, unfolding across several developmental stages. These findings, their generalizability, and implications for practice should be carefully considered in the context of several limitations that this sample was influenced by: limitations in reliability and selection of variables, lack of diversity within the sample, as well as the extraneous variables related to overall economic and political backdrop.

  12. Vital statistics of Triatominae (Hemiptera: Reduviidae) under laboratory conditions: III. Rhodnius neglectus.

    PubMed

    Rabinovich, Jorge Eduardo; Nieves, Eliana Lorena

    2011-07-01

    Five cohorts of 100 eggs of Rhodnius neglectus Lent 1954 (Hemiptera Reduviidae) were reared simultaneously in the laboratory under constant conditions (26 +/- 1 degrees C and 60 +/- 10% RH), with mortality and fecundity data recorded weekly. We calculated stage-specific developmental times, age-specific mortality and fecundity, stage-specific and total preadult mortality, and the intrinsic rate of natural increase (r0 = 0.21), the finite population growth rate (h = 1.23), the net reproductive rate (R0 = 314.24), and the generation time (T = 21.45 wk). Elasticity analysis showed that the dominant life-history traits determining lamda were the adult female survival, and the survival of instar V nymphs (molting into adult females). Adult females dominated the stage-specific reproductive value, and the egg stage dominated the stable stage distribution (SSD). The damping ratio (p = 1.11) suggests a relatively rapid period of recovery to a disturbed SSD. Results were compared with previous values from the literature and conform relatively well, considering that environmental conditions were not always the same. Compared with two other species of the same genus, Rhodnius neivai Lent 1953 and Rhodnius prolixus Stål 1859, R. neglectus ranked higher in fecundity (total eggs/ female /life) and in female longevity, intermediate in the intrinsic rate of natural increase (r0), and lower in developmental time and mortality. By fitting a logistic model of population growth to the density field values of a spontaneous colonization of two field experimental chicken coops we estimated the intrinsic rate of natural increase and carrying capacity parameters, and compared the former with our laboratory results.

  13. Quality of Life Assessment After Concurrent Chemoradiation for Invasive Bladder Cancer: Results of a Multicenter Prospective Study (GETUG 97-015)

    SciTech Connect

    Lagrange, Jean-Leon; Bascoul-Mollevi, Caroline; Geoffrois, Lionnel; Beckendorf, Veronique; Ferrero, Jean-Marc; Joly, Florence; Allouache, Nedjila; Bachaud, Jean-Marc; Chevreau, Christine; Kramar, Andrew; Chauvet, Bruno

    2011-01-01

    Purpose: To evaluate bladder preservation and functional quality after concurrent chemoradiotherapy for muscle-invasive cancer in 53 patients included in a Phase II trial. Patient and Methods: Pelvic irradiation delivered 45Gy, followed by an 18-Gy boost. Concurrent chemotherapy with cisplatin and 5-fluorouracil by continuous infusion was performed at Weeks 1, 4, and 7 during radiotherapy. Patients initially suitable for surgery were evaluated with macroscopically complete transurethral resection after 45Gy, followed by radical cystectomy in case of incomplete response. The European Organization for Research and Treatment of Cancer quality of life questionnaire QLQ-C30, specific items on bladder function, and the Late Effects in Normal Tissues-Subjective, Objective, Management, and Analytic (LENT-SOMA) symptoms scale were used to evaluate quality of life before treatment and 6, 12, 24, and 36 months after treatment. Results: Median age was 68 years for 51 evaluable patients. Thirty-two percent of patients had T2a tumors, 46% T2b, 16% T3, and 6% T4. A visibly complete transurethral resection was possible in 66%. Median follow-up was 8 years. Bladder was preserved in 67% (95% confidence interval, 52-79%) of patients. Overall survival was 36% (95% confidence interval, 23-49%) at 8 years for all patients, and 45% (28-61%) for the 36 patients suitable for surgery. Satisfactory bladder function, according to LENT-SOMA, was reported for 100% of patients with preserved bladder and locally controlled disease 6-36 months after the beginning of treatment. Satisfactory bladder function was reported for 35% of patients before treatment and for 43%, 57%, and 29%, respectively, at 6, 18, and 36 months. Conclusions: Concurrent chemoradiation therapy allowed bladder preservation with tumor control for 67% patients at 8 years. Quality of life and quality of bladder function were satisfactory for 67% of patients.

  14. Brain Injury After Proton Therapy or Carbon Ion Therapy for Head-and-Neck Cancer and Skull Base Tumors

    SciTech Connect

    Miyawaki, Daisuke Murakami, Masao; Demizu, Yusuke; Sasaki, Ryohei; Niwa, Yasue; Terashima, Kazuki; Nishimura, Hideki; Hishikawa, Yoshio; Sugimura, Kazuro

    2009-10-01

    Purpose: To assess the incidence of early delayed or late morbidity of Brain after particle therapy for skull base tumors and head-and-neck cancers. Methods and Materials: Between May 2001 and December 2005, 59 patients with cancerous invasion of the skull base were treated with proton or carbon ion therapy at the Hyogo Ion Beam Medical Center. Adverse events were assessed according to the magnetic resonance imaging findings (late effects of normal tissue-subjective, objective, management, analytic [LENT-SOMA]) and symptoms (Common Terminology Criteria for Adverse Events [CTCAE], version 3.0). Dose-volume histograms were used to analyze the relationship between the dose and volume of the irradiated brain and the occurrence of brain injury. The median follow-up time was 33 months. Results: Of the 48 patients treated with proton therapy and 11 patients treated with carbon ion radiotherapy, 8 (17%) and 7 (64%), respectively, developed radiation-induced brain changes (RIBCs) on magnetic resonance imaging (LENT-SOMA Grade 1-3). Four patients (7%) had some clinical symptoms, such as vertigo and headache (CTCAE Grade 2) or epilepsy (CTCAE Grade 3). The actuarial occurrence rate of RIBCs at 2 and 3 years was 20% and 39%, respectively, with a significant difference in the incidence between the proton and carbon ion radiotherapy groups. The dose-volume histogram analyses revealed significant differences between Brain lobes with and without RIBCs in the actuarial volume of brain lobes receiving high doses. Conclusion: Particle therapies produced minimal symptomatic brain toxicities, but sequential evaluation with magnetic resonance imaging detected a greater incidence of RIBCs. Significant differences were observed in the irradiated brain volume between Brain lobes with and without RIBCs.

  15. A randomized prospective study of rehabilitation therapy in the treatment of radiation-induced dysphagia and trismus.

    PubMed

    Tang, Y; Shen, Q; Wang, Y; Lu, K; Wang, Y; Peng, Y

    2011-01-01

    To evaluate the therapeutic effect of rehabilitation therapy on radiation-induced dysphagia and trismus in nasopharyngeal carcinoma (NPC) patients after radiotherapy. 43 NPC patients after radiotherapy were included. Patients were randomly assigned to either the rehabilitation group or a control group. Both groups were subjected to routine treatment, while the rehabilitation group also received rehabilitation therapy for 3 months. The severity of dysphagia was assessed using the water swallow test, while trismus was evaluated with the LENT/SOMA score and the interincisor distance (IID). The water swallow test, the LENT/SOMA score, as well as IID for both groups before and after treatment were analyzed and compared. After treatment, the rehabilitation group displayed a significant improvement in swallowing function, while the control group did not. The efficacy rate (percentage of patients with excellent or effective results) of rehabilitation group was higher than that of control group (77% vs. 43%), and the difference was statistically significant (ϰ(2) = 5.32, p = 0.02). IID pretreatment and posttreatment did not show much difference in the rehabilitation group, while in the control group IID significantly decreased posttreatment (1.1 ± 0.36 cm vs.1.8 ± 0.56 cm, p = 0.001). Although the mean IID in patients of both groups decreased after the 3 month follow-up, the decrease in the rehabilitation group was less than that of the control group (0.19 ± 0.5 cm vs. 0.69 ± 0.56 cm, p = 0.004 ). The efficacy rate of trismus in the rehabilitation group was significantly higher than that of the control group (64% vs. 28%, ϰ(2) = 5.31, p = 0.02). Rehabilitation training can improve swallow function and slow down the progress of trismus in NPC patients following radiotherapy.

  16. The past, present, and future of bone morphometry: its contribution to an improved understanding of bone biology.

    PubMed

    Jee, Webster S S

    2005-01-01

    It was not until the 1950s that a better paradigm for bone biology evolved, which led to the birth of bone histomorphometry. Two clinicians, Harold Frost (1958-1964) and Lent Johnson (1964), were responsible for the paradigm stating that the primary function of bone is mechanical load bearing with subsidiary function to participate in plasma calcium homeostasis to support hematopoesis. Dynamic bone histomorphometry was born when Milch et al. (1958) discovered bone localization of tetracycline and Frost generated the methodology to study tetracycline-based dynamic histological analysis of cortical bone remodeling (1961-1965). Dynamic bone histomorphometry did not blossom until Frost, while a Sun Valley Workshop participant, developed it to address trabecular bone dynamics. The combination of Arnold (1948) producing thin sections of plastic-embedded undecalcified bone and Frost's (1977-1983) modification of dynamic cortical bone histology for cancellous bone made it possible to study tetracycline-based dynamic histomorphometry of cancellous bone. It led to the better understanding of basic metabolic unit (BMU) remodelling and to Frost's mechanostat hypothesis, and characterized the rat model to accelerate the development of several drugs in the treatment of bone diseases. Currently, dynamic bone histomorphometry has contributed to studies in bone's mechanical usage windows, mechanical usage setpoint hypothesis, muscle-bone relations, marrow-bone relations, the Utah paradigm of musculoskeletal physiology, apoptosis, genetics (transgenic mice) and bone structure, bone quality, the lacunocanalicular network and bone modelling, and remodeling hypothesis, osteocyte role as mechanosensory, chemosensory, and regulatory in bone maintenance, targeted and untargeted remodeling, the role of permissive agents, etc., items in bone biology expounded briefly by Lent Johnson (1965) and continuously by Harold Frost at the Sun Valley Workshop (1965-2003). Finally, "What's next

  17. Modélisation de la dynamique de la chaîne peptidique des protéines en solution par RMN à travers les couplages dipolaires

    NASA Astrophysics Data System (ADS)

    Bouvignies, G.; Bernadó, P.; Blackledge, M.

    2005-11-01

    L'activité d'une protéine est liée non seulement à sa structure, mais également à sa dynamique, et il est important de connaître la nature de ses mouvements pour comprendre sa fonction biologique. La résonance magnétique nucléaire est particulièrement utile pour étudier la dynamique d'une molécule en solution sur une gamme de temps de corrélation très large. En particulière, la relaxation des spins 15N ou 13C donne accès aux mouvements moléculaires avec les temps caractéristiques entre les dizaines de picosecondes et le temps de corrélation rotationelle de la molécule (autour de 10ns pour une protéine monomérique de 20 kD à 300 K). Les vitesses de relaxation dépendent de la flexibilité de chaque site, et peuvent être caractérisé en termes d'amplitude et de temps caractéristique locale. La précision de ces paramètres et sa compréhension en termes de fonction exigent que la réorientation globale de la molécule soit correctement prise en compte. Ces méthodes expérimentales, qui seront présentées ici brièvement, font maintenant partie de la panoplie d'expériences appliquées dans l'étude de la relation structure-dynamique d'une protéine et ses partenaires. Néanmoins les mouvements plus lents, entre la nano et la milliseconde, sont plus difficiles à étudier, et il y a très peu d'information disponible sur la nature de la dynamique de la chaîne peptidique dans cette gamme de temps par RMN. Très récemment de nouvelles méthodologies ont été proposées, basées sur l'alignement préférentiel d'une protéine par rapport au champ magnétique, induit par dissolution de la molécule dans un cristal liquide très dilué. Dans ces conditions les changements conformationels sur des temps caractéristique plus lents (jusqu'au millisecondes) peuvent être étudiés. Nous présenterons cette technique, et quelques résultats, comparant la dynamique rapide (ps-ns), et plus lente le long de la chaîne peptidique de quatre protéines.

  18. [CT densitometry for the grading of subcutaneous fibrosis after the photon-neutron therapy of malignant salivary gland tumors].

    PubMed

    Eich, H T; Eich, P D; Stuschke, M; Müller, R D; Sack, H

    1999-03-01

    To evaluate alternative treatment regimen e.g. neutron therapy determination of treatment efficacy as well as side effects is important. Sensitivity of computed tomography (CT) in detecting changes of connective tissue after neutron therapy was examined. In the course of their follow-up period (median 45 months) 12 patients with malignant salivary gland tumors who had postoperatively received neutron (1/12) or photon/neutron therapy (11/12) were examined by means of CT densitometry on 3 representative scans in the area of radiotherapy. In 3 ROI (regions of interest) in subcutaneous fatty tissue the density at the irradiated and the non-irradiated side was determined according to Hounsfield units (HU) and the average density was calculated. The average density of both sides was compared and correlated with the clinical grade of fibrosis according to LENT SOMA. All CT measurements (216 ROI, 18 ROI per patient) showed higher density levels on the irradiated side than on the non-irradiated side. The average density on the irradiated side was -57.7 +/- 4.7 HU and on the non-irradiated side -69.4 +/- 5.8 HU (p = 0.002). In 3/12 patients a clinical fibrosis was not seen; however, the relative density measured on the irradiated and non-irradiated side deviated by up to 8%. This could have been caused by minimal changes not being noticed by either patient and examiner. In patients with determined fibrosis Grade 1 (8/12) the relative density deviation was 4 to 39%. In 1/12 patients with determined fibrosis Grade 2 the relative density deviation was 50% (Figures 1a and 1b). Fibrosis Grade 3 and 4 did not occur (Table 1). Fibrosis is correlated with an increasing value of HU of the tissue density in CT. With the described method it is possible to graduate radiation induced subcutaneous fibrosis in correlation to the clinical fibrosis grade according to LENT SOMA. In the patients we examined subcutaneous fibroses after photon/neutron therapy were moderate. Especially in

  19. Late radiation side effects, cosmetic outcomes and pain in breast cancer patients after breast-conserving surgery and three-dimensional conformal radiotherapy : Risk-modifying factors.

    PubMed

    Hille-Betz, Ursula; Vaske, Bernhard; Bremer, Michael; Soergel, Philipp; Kundu, Sudip; Klapdor, Rüdiger; Hillemanns, Peter; Henkenberens, Christoph

    2016-01-01

    The purpose of this work was to identify parameters influencing the risk of late radiation side effects, fair or poor cosmetic outcomes (COs) and pain in breast cancer patients after breast-conserving therapy (BCT) and three-dimensional conformal radiotherapy (3D-CRT). Between 2006 and 2013, 159 patients were treated at the Hannover Medical School. Physician-rated toxicity according to the LENT-SOMA criteria, CO and pain were assessed by multivariate analysis. LENT-SOMA grade 1-4 toxicity was observed as follows: fibrosis 10.7 %, telangiectasia 1.2 %, arm oedema 8.8 % and breast oedema 5.0 %. In addition, 15.1 % of patients reported moderate or severe breast pain, and 21.4 % complained about moderate or severe pain in the arm or shoulder. In multivariate analysis, axillary clearing (AC) was significantly associated with lymphoedema of the arm [odds ratio (OR) 4.37, p = 0.011, 95 % confidence interval (CI) 1.4-13.58]. Breast oedema was also highly associated with AC (OR 10.59, p = 0.004, 95 % CI 2.1-53.36), a ptosis grade 2/3 or pseudoptosis and a bra size ≥ cup C (OR 5.34, p = 0.029, 95 % CI 1.2-24.12). A ptosis grade 2/3 or pseudoptosis and a bra size ≥ cup C were the parameters significantly associated with an unfavourable CO (OR 3.19, p = 0.019, 95 % CI 1.2-8.4). Concerning chronic breast pain, we found a trend related to the prescribed radiation dose including boost (OR 1.077, p = 0.060, 95 % CI 0.997-1.164). Chronic shoulder or arm pain was statistically significantly associated with lymphoedema of the arm (OR 3.9, p = 0.027, 95 % CI 1.17-13.5). Chronic arm and breast oedema were significantly influenced by the extent of surgery (AC). Ptotic and large breasts were significantly associated with unfavourable COs and chronic breast oedema. Late toxicities exclusive breast pain were not associated with radiotherapy parameters.

  20. Martian Mixed Layer during Pathfinder Mission

    NASA Astrophysics Data System (ADS)

    Martinez, G. M.; Valero, F.; Vazquez, L.

    2008-09-01

    In situ measurements of the Martian Planetary Boundary Layer (MPBL) encompass only the sur- face layer. Therefore, in order to fully address the MPBL, it becomes necessary to simulate somehow the behaviour of the martian mixed layer. The small-scale processes that happen in the MPBL cause GCM's ([1], [2]) to describe only partially the turbulent statistics, height, convective scales, etc, of the surface layer and the mixed layer. For this reason, 2D and 3D martian mesoscale models ([4], [5]), and large eddy simulations ([4], [6], [7], [8]) have been designed in the last years. Although they are expected to simulate more accurately the MPBL, they take an extremely expensive compu- tational time. Alternatively, we have derived the main turbu- lent characteristics of the martian mixed layer by using surface layer and mixed layer similarity ([9], [10]). From in situ temperature and wind speed measurements, together with quality-tested simu- lated ground temperature [11], we have character- ized the martian mixed layer during the convective hours of Pathfinder mission Sol 25. Mean mixed layer turbulent statistics like tem- perature variance < σ? >, horizontal wind speed variance < σu,v >, vertical wind speed variance < σw >, viscous dissipation rate < ǫ >, and turbu- lent kinetic energy < e > have been calculated, as well as the mixed layer height zi, and the convective scales of wind w? and temperature θ?. Our values, obtained with negligible time cost, match quite well with some previously obtained results via LES's ([4] and [8]). A comparisson between the above obtained mar- tian values and the typical Earth values are shown in Table 1. Convective velocity scale w doubles its counterpart terrestrial typical value, as it does the mean wind speed variances < σu,v > and < σw >. On the other hand, the temperature scale θ? and the mean temperature variance < σ > are virtually around one order higher on Mars. The limitations of these results concern the va- lidity

  1. 70 Gy versus 80 Gy in localized prostate cancer: 5-year results of GETUG 06 randomized trial.

    PubMed

    Beckendorf, Véronique; Guerif, Stéphane; Le Prisé, Elisabeth; Cosset, Jean-Marc; Bougnoux, Agnes; Chauvet, Bruno; Salem, Naji; Chapet, Olivier; Bourdain, Sylvain; Bachaud, Jean-Marc; Maingon, Philippe; Hannoun-Levi, Jean-Michel; Malissard, Luc; Simon, Jean-Marc; Pommier, Pascal; Hay, Men; Dubray, Bernard; Lagrange, Jean-Léon; Luporsi, Elisabeth; Bey, Pierre

    2011-07-15

    To perform a randomized trial comparing 70 and 80 Gy radiotherapy for prostate cancer. A total of 306 patients with localized prostate cancer were randomized. No androgen deprivation was allowed. The primary endpoint was biochemical relapse according to the modified 1997-American Society for Therapeutic Radiology and Oncology and Phoenix definitions. Toxicity was graded using the Radiation Therapy Oncology Group 1991 criteria and the late effects on normal tissues-subjective, objective, management, analytic scales (LENT-SOMA) scales. The patients' quality of life was scored using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire 30-item cancer-specific and 25-item prostate-specific modules. The median follow-up was 61 months. According to the 1997-American Society for Therapeutic Radiology and Oncology definition, the 5-year biochemical relapse rate was 39% and 28% in the 70- and 80-Gy arms, respectively (p = .036). Using the Phoenix definition, the 5-year biochemical relapse rate was 32% and 23.5%, respectively (p = .09). The subgroup analysis showed a better biochemical outcome for the higher dose group with an initial prostate-specific antigen level >15 ng/mL. At the last follow-up date, 26 patients had died, 10 of their disease and none of toxicity, with no differences between the two arms. According to the Radiation Therapy Oncology Group scale, the Grade 2 or greater rectal toxicity rate was 14% and 19.5% for the 70- and 80-Gy arms (p = .22), respectively. The Grade 2 or greater urinary toxicity was 10% at 70 Gy and 17.5% at 80 Gy (p = .046). Similar results were observed using the LENT-SOMA scale. Bladder toxicity was more frequent at 80 Gy than at 70 Gy (p = .039). The quality-of-life questionnaire results before and 5 years after treatment were available for 103 patients with no differences found between the 70- and 80-Gy arms. High-dose radiotherapy provided a better 5-year biochemical outcome with slightly

  2. 70 Gy Versus 80 Gy in Localized Prostate Cancer: 5-Year Results of GETUG 06 Randomized Trial;Prostate cancer; Dose escalation; Conformal radiotherapy; Randomized trial

    SciTech Connect

    Beckendorf, Veronique; Guerif, Stephane; Le Prise, Elisabeth; Cosset, Jean-Marc; Bougnoux, Agnes; Chauvet, Bruno; Salem, Naji; Chapet, Olivier; Bourdain, Sylvain; Bachaud, Jean-Marc; Maingon, Philippe; Hannoun-Levi, Jean-Michel; Malissard, Luc; Simon, Jean-Marc; Pommier, Pascal; Hay, Men; Dubray, Bernard; Lagrange, Jean-Leon; Luporsi, Elisabeth; Bey, Pierre

    2011-07-15

    Purpose: To perform a randomized trial comparing 70 and 80 Gy radiotherapy for prostate cancer. Patients and Methods: A total of 306 patients with localized prostate cancer were randomized. No androgen deprivation was allowed. The primary endpoint was biochemical relapse according to the modified 1997-American Society for Therapeutic Radiology and Oncology and Phoenix definitions. Toxicity was graded using the Radiation Therapy Oncology Group 1991 criteria and the late effects on normal tissues-subjective, objective, management, analytic scales (LENT-SOMA) scales. The patients' quality of life was scored using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire 30-item cancer-specific and 25-item prostate-specific modules. Results: The median follow-up was 61 months. According to the 1997-American Society for Therapeutic Radiology and Oncology definition, the 5-year biochemical relapse rate was 39% and 28% in the 70- and 80-Gy arms, respectively (p = .036). Using the Phoenix definition, the 5-year biochemical relapse rate was 32% and 23.5%, respectively (p = .09). The subgroup analysis showed a better biochemical outcome for the higher dose group with an initial prostate-specific antigen level >15 ng/mL. At the last follow-up date, 26 patients had died, 10 of their disease and none of toxicity, with no differences between the two arms. According to the Radiation Therapy Oncology Group scale, the Grade 2 or greater rectal toxicity rate was 14% and 19.5% for the 70- and 80-Gy arms (p = .22), respectively. The Grade 2 or greater urinary toxicity was 10% at 70 Gy and 17.5% at 80 Gy (p = .046). Similar results were observed using the LENT-SOMA scale. Bladder toxicity was more frequent at 80 Gy than at 70 Gy (p = .039). The quality-of-life questionnaire results before and 5 years after treatment were available for 103 patients with no differences found between the 70- and 80-Gy arms. Conclusion: High-dose radiotherapy provided a

  3. Conventional karyotyping and fluorescence in situ hybridization: an effective utilization strategy in diagnostic adult acute myeloid leukemia.

    PubMed

    He, Rong; Wiktor, Anne E; Hanson, Curtis A; Ketterling, Rhett P; Kurtin, Paul J; Van Dyke, Daniel L; Litzow, Mark R; Howard, Matthew T; Howard, Matthew H; Reichard, Kaaren K

    2015-06-01

    Cytogenetics defines disease entities and predicts prognosis in acute myeloid leukemia (AML). Conventional karyotyping provides a comprehensive view of the genome, while fluorescence in situ hybridization (FISH) detects targeted abnormalities. The aim of this study was to compare the utility of karyotyping and FISH in adult AML. We studied 250 adult AML cases with concurrent karyotyping and FISH testing. Karyotyping was considered adequate when 20 or more metaphases were analyzed. In total, 220 cases had adequate karyotyping and were classified as normal karyotype/normal FISH (n = 92), normal karyotype/abnormal FISH (n = 4), abnormal karyotype/normal FISH (n = 8), and abnormal karyotype/abnormal FISH (n = 116). The overall karyotype/FISH concordance rate was 97.7% with five discordant cases identified, four from the normal karyotype/abnormal FISH group and one from the abnormal karyotype/abnormal FISH group. No karyotype/FISH discordance was seen in the abnormal karyotype/normal FISH group for the FISH probes evaluated. FISH lent prognostic information in one (0.5%) of 220 cases with normal karyotype/abnormal FISH: CBFB-MYH11 fusion, indicating favorable prognosis. In adult AML, FISH rarely provides additional information when karyotyping is adequate. We therefore propose an evidence-based, cost-effective algorithmic approach for routine conventional karyotype and FISH testing in adult AML workup. Copyright© by the American Society for Clinical Pathology.

  4. The pleasures and perils of prophetic advocacy: Henry E. Sigerist and the politics of medical reform.

    PubMed Central

    Fee, E

    1996-01-01

    Henry E. Sigerist, an internationally renowned medical historian, played a surprisingly important and visible role in American medical politics in the 1930s and 1940s. Born in Paris of Swiss parents, he was professor in Leipzig, Germany, before coming to the United States in 1932 as professor of the history of medicine at Johns Hopkins University. Once in America. Sigerist became deeply involved in medical politics and the campaign for national health insurance. He argued that individualized medical practice was outdated and should gradually be superseded by state-run and state-financed health services. National health insurance was but one step in this historical progression. Sigerist thus lent the weight of history itself to the cause of medical care reform. The charming and erudite Sigerist was welcomed by the leaders of academic medicine in America. Soon, he emerged as a spokesman of the left wing of the medical profession, an effective and popular speaker and an impassioned advocate of socialized medicine. This paper traces Sigerist's political ideas and activities, and his contributions toward medical care reform in the United States. Images p1639-a p1642-a PMID:8916536

  5. Behavioural variant frontotemporal dementia: clinical and therapeutic approaches.

    PubMed

    Fernández-Matarrubia, M; Matías-Guiu, J A; Moreno-Ramos, T; Matías-Guiu, J

    2014-10-01

    Behavioural variant frontotemporal dementia (bvFTD) is the most frequent presentation in the clinical spectrum of frontotemporal dementia (FTD) and it is characterised by progressive changes in personality and conduct. Major breakthroughs in molecular biology and genetics made during the last two decades have lent us a better understanding of this syndrome, which may be the first manifestation in many different neurodegenerative diseases. We reviewed the main epidemiological, clinical, diagnostic and therapeutic aspects of bvFTD. Most cases manifest sporadically and the average age of onset is 58 years. Current criteria for bvFTD propose three levels of diagnostic certainty: possible, probable, and definite. Clinical diagnosis is based on a detailed medical history provided by family members and caregivers, in conjunction with neuropsychological testing. Treatments which have been used in bvFDT to date are all symptomatic and their effectiveness is debatable. New drugs designed for specific molecular targets that are implicated in frontotemporal lobar degeneration are being developed. BvFDT is a frequent cause of dementia. It is a non-specific syndrome associated with heterogeneous histopathological and biomolecular findings. The definition of clinical subtypes complemented by biomarker identification may help predict the underlying pathology. This knowledge, along with the development of drugs designed for molecular targets, will offer new treatment possibilities. Copyright © 2013 Sociedad Española de Neurología. Published by Elsevier Espana. All rights reserved.

  6. The analyst's narrative function: Inventing a possibility.

    PubMed

    Pereira da Silva, Maria Cecília

    2017-02-01

    This article describes a psychic function common to analysts that was gradually revealed through clinical work with children. It is a psychic quality derived from function α, which involves analysts' capacity for reverie - their narrative function. The author presents two clinical situations where this function developed in the analytic field in relation to patients' difficulty in symbolizing. In the first case there was an early traumatic experience unavailable for representation. The analyst lent the patient her ability to represent and produced a narrative that made it possible to create a world of phantasies and transform nightmares into 'dreamable' dreams. In other words, she removed the quality of unbearable, irrepresentable reality that characterized those raw experiences encrypted in the psyche. In the second case the analyst's narrative function sought to connect with the isolation, the shell that housed a child suffering from an autistic disorder whose ability to represent had not been established. The analyst provided meaning for the patient's repetitive, stereotyped play, thus weaving the child's subjectivity and gradually introducing a notion of alterity. The author seeks to show how this function, in the thematic construction of the session, facilitated both the working-through of a traumatic situation (with the ability to share representations) and the constitution of the psychic fabric. Copyright © 2016 Institute of Psychoanalysis.

  7. The Association of Academic Health Sciences Libraries Annual Statistics: an exploratory twenty-five-year trend analysis

    PubMed Central

    Byrd, Gary D.; Shedlock, James

    2003-01-01

    This paper presents an exploratory trend analysis of the statistics published over the past twenty-four editions of the Annual Statistics of Medical School Libraries in the United States and Canada. The analysis focuses on the small subset of nineteen consistently collected data variables (out of 656 variables collected during the history of the survey) to provide a general picture of the growth and changing dimensions of services and resources provided by academic health sciences libraries over those two and one-half decades. The paper also analyzes survey response patterns for U.S. and Canadian medical school libraries, as well as osteopathic medical school libraries surveyed since 1987. The trends show steady, but not dramatic, increases in annual means for total volumes collected, expenditures for staff, collections and other operating costs, personnel numbers and salaries, interlibrary lending and borrowing, reference questions, and service hours. However, when controlled for inflation, most categories of expenditure have just managed to stay level. The exceptions have been expenditures for staff development and travel and for collections, which have both outpaced inflation. The fill rate for interlibrary lending requests has remained steady at about 75%, but the mean ratio of items lent to items borrowed has decreased by nearly 50%. PMID:12883578

  8. A retrospective study on 69 cases of maxillary tooth transposition.

    PubMed

    Cho, Shiu-yin; Chu, Vanessa; Ki, Yung

    2012-01-01

    The published literature on tooth transposition includes only a few studies that have involved more than 50 subjects. The aim of the present study was to investigate the prevalence of true maxillary tooth transposition and possible associated dental anomalies in a larger sample of children. The dental records and radiographs of children who had been diagnosed as having true maxillary tooth transposition at a School Dental Clinic in Hong Kong were studied retrospectively. Data were analyzed for sex and side distribution, as well as for associated dental anomalies. Trends of differences were analyzed statistically using the Fisher exact or chi-squared test. A total of 69 cases of true maxillary tooth transposition were identified and studied; its prevalence in Hong Kong Chinese children was 0.81%. More females than males were affected, and the difference between the sexes was statistically significant (P < 0.05). The prevalence of congenitally missing teeth, microdontia of the maxillary lateral incisors or dental impaction was higher in patients with maxillary tooth transposition than in the general population (P < 0.05, P < 0.0005, and P < 0.0001, respectively). The fact that patients with maxillary tooth transposition were more likely to have congenital absence or microdontia of the maxillary lateral incisors lent further support to the contention that a developmental field defect plays a role in the pathogenesis of maxillary tooth transposition.

  9. Neuroimaging of Fear-Associated Learning

    PubMed Central

    Greco, John A; Liberzon, Israel

    2016-01-01

    Fear conditioning has been commonly used as a model of emotional learning in animals and, with the introduction of functional neuroimaging techniques, has proven useful in establishing the neurocircuitry of emotional learning in humans. Studies of fear acquisition suggest that regions such as amygdala, insula, anterior cingulate cortex, and hippocampus play an important role in acquisition of fear, whereas studies of fear extinction suggest that the amygdala is also crucial for safety learning. Extinction retention testing points to the ventromedial prefrontal cortex as an essential region in the recall of the safety trace, and explicit learning of fear and safety associations recruits additional cortical and subcortical regions. Importantly, many of these findings have implications in our understanding of the pathophysiology of psychiatric disease. Recent studies using clinical populations have lent insight into the changes in regional activity in specific disorders, and treatment studies have shown how pharmaceutical and other therapeutic interventions modulate brain activation during emotional learning. Finally, research investigating individual differences in neurotransmitter receptor genotypes has highlighted the contribution of these systems in fear-associated learning. PMID:26294108

  10. Liposarcome paratesticulaire métastatique

    PubMed Central

    Fahsi, Otheman; Kallat, Adil; Ouazize, Hicham; Dergamoun, Hamza; Sayegh, Hachem El; Iken, Ali; Benslimane, Lounis; Nouini, Yassine

    2017-01-01

    Nous rapportons le cas dramatique d'un liposarcome à cellules rondes paratesticulaire d'emblée métastatique chez un jeune homme de 18 ans. Il s'agit d'une tumeur rare qui se développe à partir du tissu graisseux entourant le testicule et le cordon spermatique. Les signes cliniques et radiologiques sont peu spécifiques, le diagnostic n'est en général fait que sur la pièce opératoire. Le traitement consiste en une orchidéctomie radicale par voie inguinale, parfois élargie aux structures adjacentes. La radiothérapie adjuvante pourrait avoir une place en cas de masse localement avancée ou en cas de résection incomplète. Malgré une évolutivité lente, une surveillance prolongée s'impose du fait du risque élevé de récidive tardive. PMID:28819522

  11. UV photography of the earth and the moon

    NASA Technical Reports Server (NTRS)

    1973-01-01

    The fundamental aim of this experiment was the acquisition of ultraviolet photographs of the earth and the moon that could be used to interpret similar imagery of Mars and Venus. Venus shows no markings whatever when viewed in visible light, a phenomenon that is in keeping with its immensely thick atmosphere and perpetual cloud cover, but in the near ultraviolet, the planet exhibits low contrast markings which vary in position and appearance with time. Mars posed just the opposite problem from Venus at wavelengths below 4500 A, Mars shows very little detail, sometimes none at all, whereas at longer wavelengths, the surface is clearly visible. Occasionally observers have reported that this obscuration has lifted and the ground has become visible at the shorter wavelengths as well. Such events have been labeled blue clearings and led to the suggestion that the ultraviolet obscuration was caused by an atmospheric haze. Mariner 6 and 7 observations of Mars failed to find such a haze and lent support to the alternative view that ascribed the absence of detail on UV photographs to a simple lack of contrast between Martian surface features at these wavelengths.

  12. Malignant Tumors of the Nasal Cavity and Paranasal Sinuses: Long-Term Outcome and Morbidity With Emphasis on Hypothalamic-Pituitary Deficiency

    SciTech Connect

    Snyers, An Janssens, Geert; Twickler, Marcel B.; Hermus, Ad R.; Takes, Robert P.; Kappelle, Arnoud C.; Merkx, Matthias A.W.; Dirix, Piet; Kaanders, Johannes H.A.M.

    2009-04-01

    Purpose: To evaluate the long-term outcome after surgery and radiotherapy for patients with sinonasal cancer and assess late toxicity, with special emphasis on hypothalamic-pituitary dysfunction. Methods and Materials: A retrospective analysis of 168 patients treated for sinonasal cancer in a single institute between 1986 and 2006. A more detailed analysis was performed on a subgroup of 76 patients with adenocarcinoma or squamous cell carcinoma treated with curative intent. Long-term survivors were evaluated for late toxicity by a multidisciplinary team using the late effects of normal tissues (LENT SOMA) scoring system. Additional endocrinologic tests were performed for assessment of hypothalamic-pituitary function. Results: Five-year actuarial local control and overall survival rates were 62% and 35% for all patients and 64% and 42% for the subgroup with squamous cell carcinoma and adenocarcinoma. In multivariate analysis, T stage was the only significant factor predicting local relapse (79% at 5 years for T1-T3 vs. 53% for T4; p = 0.006). Sinonasal mucosal melanomas had the highest rate of regional failure (33% at 5 years). Thirteen of 21 patients (62%) evaluated at the late morbidity clinic had hormonal disturbances, of whom 5 (24%) had definitive evidence of hypopituitarism with multiple hormonal deficiencies. Conclusion: Local failure is the dominant cause of treatment failure for patients with sinonasal cancer, with T4 stage the only independent predictor. Because of a high rate of radiation-induced hypopituitarism, we recommend endocrinologic surveillance for these patients.

  13. Cell Churches and Stem Cell Marketing in South Korea and the United States.

    PubMed

    Sipp, Douglas

    2016-05-23

    The commercial provision of putative stem cell-based medical interventions in the absence of conclusive evidence of safety and efficacy has formed the basis of an unregulated industry for more than a decade. Many clinics offering such supposed stem cell treatments include statements about the 'ethical' nature of somatic (often colloquially referred to as 'adult' stem cells) stem cells, in specific contrast to human embryonic stem cells (hESCs), which have been the subject of intensive political, legal, and religious controversy since their first derivation in 1998. Christian groups-both Roman Catholic and evangelical Protestant-in many countries have explicitly promoted the medical potential and current-day successes in the clinical application of somatic stem cells, lending indirect support to the activities of businesses marketing stem cells ahead of evidence. In this article, I make a preliminary examination of how the structures and belief systems of certain churches in South Korea and the United States, both of which are home to significant stem cell marketing industries, has complemented other factors, including national biomedical funding initiatives, international economic rivalries, permissive legal structures, which have lent impetus to a problematic and often exploitative sector of biomedical commerce.

  14. Using a safe taxi service to transport newborn babies home from hospital.

    PubMed

    Eventov-Friedman, S; Bar-Oz, B; Zisk-Rony, R Y

    2014-01-01

    To evaluate an intervention to enhance parents' use of car safety seats (CSSs) for their newborn baby's first journey home from the hospital in a population not usually exposed to television, internet and mainstream printed media. Parents of newborn babies who did not bring a CSS to the hospital before their baby was discharged were lent a CSS to use in a 'safe taxi' service. All taxi drivers were trained to install the CSS safely. The intervention was evaluated using preprogramme questionnaires and follow-up interviews 4-8 weeks after discharge. Twelve parents participated in the intervention during the study period (January to April 2011) and in the evaluation process. Eleven couples were Jewish and one was Muslim. Most (75%) reported that they had not previously used CSS routinely and the reason was not financial. Following the 'safe taxi' intervention, 83% reported the use of CSS when travelling in all vehicles (excluding buses). On follow-up, most participants reported that the intervention increased their awareness and the use of CSS. The intervention, targeted at this specific population, was well received by the parents, increased awareness, changed practices and assured that more newborns travelled home safely in a CSS. ©2013 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

  15. Physicians' use of computer software in answering clinical questions.

    PubMed Central

    Osheroff, J A; Bankowitz, R A

    1993-01-01

    Descriptive data about the use of medical information software were gathered from physicians who were early users of these resources. Eight clinically active internists and medical subspecialists were lent a microcomputer loaded with six commercially available medical information software products. Participants used the software for two weeks to answer questions arising in their practice and completed written questionnaires. They recorded a total of 50 questions (between 3 and 11 per participant per two-week study period). Using the workstation, participants answered 20 questions (40% of the total), partially answered 16 questions (32%), and did not obtain useful information for 14 questions (28%). Participants found answers outside the workstation to 8 of the 14 questions (57%) not answered by using the software. The most common question topic was drug information (16 questions, or 32% of the total). The most common problems encountered using the workstation were retrieval of incomplete information (20 questions, or 40% of the total) and difficulty navigating the software (16 questions, or 32%). Other problems included difficulty translating clinical problems into questions, inappropriate resource selection, inadequate training for using the software, and excessive time required to access information. The study highlights several opportunities for medical librarians and others involved in clinical information management to facilitate the use of computer software for solving clinical problems. PMID:8428184

  16. Bell P–63A King Cobra at the Aircraft Engine Research Laboratory

    NASA Image and Video Library

    1944-01-21

    The Army Air Forces lent the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory a Bell P–63A King Cobra in October 1943 to complement the lab's extensive efforts to improve the Allison V–1710 engine. The V–1710-powered P–63A was a single-seat fighter that could reach speeds of 410 miles per hour and an altitude of 43,000 feet. The fighter, first produced in 1942, was an improvement on Bell’s P–39, but persistent performance problems at high altitudes prevented its acceptance by the Air Corps. Instead many of the P–63s were transferred to the Soviet Union. Almost every test facility at the NACA’s engine lab was used to study the Allison V–1710 engine and its supercharger during World War II. Researchers were able to improve the efficiency, capacity and pressure ratio of the supercharger. They found that improved cooling significantly reduced engine knock in the fuel. Once the researchers were satisfied with their improvements, the new supercharger and cooling components were installed on the P–63A. The Flight Research Division first established the aircraft’s normal flight performance parameters such as speed at various altitudes, rate of climb, and peak altitude. Ensuing flights established the performance parameters of the new configuration in order to determine the improved performance. The program increased V–1710’s horsepower from 1650 to 2250.

  17. Philippines: rural electrification. Project impact evaluation report No. 15

    SciTech Connect

    Mandel, D.H.; Allgeier, P.F.; Wasserman, G.; Hickey, G.; Salazar, R.

    1980-12-01

    AID's overall evaluation of its Philippine Rural Electrification (RE) program, consisting of eight successive projects, had limited effect on the rural poor and the economic development process. This program began in 1965 and has since energized 844 (59% of the national total) Philippine municipalities, 9088 (27%) barrios, 1,159,434 (20%) households, and 101 new cooperatives; resulting in a change of schedule for total national energization from 1980 to 1987. To improve the productive capacity of the poor, cooperatives were organized and lent funds to extend electrical power into their areas. Many of the poor, however, could not afford its installation, continued use, or more than one or two light bulbs a month. Community lighting, such as street-lighting, indirectly helped the poor in various ways, such as by providing greater personal security. Those with sufficient financial resources or skills were able to use the electricity for entrepreneurial activities. RE impact upon development occurred in areas with a concentrated population, available technical skills and capital, and access to large and diverse markets. Active promotion of electricity-dependent investments and projects also increased program impact.

  18. Social cognitive determinants of ecstasy use to target in evidence-based interventions: a meta-analytical review.

    PubMed

    Peters, Gjalt-Jorn Y; Kok, Gerjo; Abraham, Charles

    2008-01-01

    The health hazards and prevalence of ecstasy use have been documented in two decades of research, but no review reporting on potentially modifiable antecedents of use is available. The aim of this study was to integrate systematically research identifying cognitive correlates of ecstasy use. Such research has the potential to identify targets for evidence-based interventions designed to discourage use. The databases PsycINFO and MedLine were searched, inclusion criteria applied to resulting hits, and descendency and ancestry approaches applied to the selected publications. Reported associations between cognitive determinants, including intention to use and ecstasy use measures, were synthesized by calculating a weighted mean effect size, r. The pattern of associations lent support both to the theory of planned behaviour (TPB) and the expectancy approach as descriptions of potentially useful determinants. Attitudes were associated most strongly with intention and use, followed by subjective norm and perceived behavioural control. Consideration of the strength of associations and the potential modifiability of identified cognitions suggests that evidence-based interventions to discourage ecstasy use should target negative expectancies, perceived behavioural control and anticipated regret, and consider tailoring perceived behavioural control elements.

  19. Multicultural counseling self-efficacy scale-racial diversity form: factor structure and test of a social cognitive model.

    PubMed

    Sheu, Hung-Bin; Rigali-Oiler, Marybeth; Lent, Robert W

    2012-01-01

    This study was conducted to gather evidence on the factor structure and concurrent criterion validity of the multicultural counseling self-efficacy scale-racial diversity form (MCSE-RD; Sheu & Lent, 2007). The MCSE-RD was designed to assess therapists' perceived capabilities in performing culturally relevant in-session behaviors in cross-racial counseling. Participants were 209 students in counseling-related graduate programs in the USA. Confirmatory factor analyses identified a bifactor structure in which responses to MCSE-RD items could be explained by one generic and three multicultural-specific counseling self-efficacy factors. Support was also found for a social cognitive model in which self-efficacy and interests in multicultural counseling mediated the effects of prior cross-racial client contacts and perceptions of multicultural training environments on intent to perform multicultural counseling in the future. Additionally, outcome expectations were predictive of multicultural counseling interests and choice goals. Implications for multicultural training and directions for future research are highlighted.

  20. A longitudinal examination of adolescent career planning and exploration using a social cognitive career theory framework.

    PubMed

    Rogers, Mary E; Creed, Peter A

    2011-02-01

    This study used social cognitive career theory (Lent, Brown, & Hackett, 1994), as a framework to investigate predictors of career choice actions, operationalised as career planning and career exploration. The model was tested cross-sectionally and longitudinally with 631 high school students enrolled in Grades 10-12. Students completed measures of self-efficacy, outcome expectations, goals, supports and personality. Results of the hierarchical regression analyses indicated strong support for self-efficacy and goals predicting career planning and exploration across all grades at T1, and predicting change in career planning and exploration from T1 to T2. Whilst support for pathways among other predictor variables (personality, contextual influences and biographic variables) to choice actions was found, these pathways varied across grades at T1, and also from T1 to T2. Implications for social cognitive career theory, career counselling practice and future research are discussed. Copyright © 2010 The Association for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  1. Prediction of job search intentions and behaviors: Testing the social cognitive model of career self-management.

    PubMed

    Lim, Robert H; Lent, Robert W; Penn, Lee T

    2016-10-01

    We present 2 studies testing the recently developed social-cognitive model of career self-management (Lent & Brown, 2013) in the context of the job search process. In the first study, a sample of 243 unemployed job seekers completed measures of job search self-efficacy, outcome expectations, social support, search intentions, conscientiousness, and perceived control (or volition) over the outcomes of the job search. The latter variable was added to the social-cognitive model to examine the possibility, derived from the psychology of working perspective, that perceived volition might moderate the relation of self-efficacy to job search intentions. The second study included 240 graduating college seniors and focused on the utility of the social-cognitive, personality, and perceived outcome control variables in predicting active engagement in the job search process. Path analyses indicated that the model generally fit the data well in both studies. In Study 1, self-efficacy and outcome expectations mediated the relations of the other predictors to job search intentions. In Study 2, job search intentions produced the primary direct path to subsequent job search behaviors; conscientiousness, support, and outcome control related to job search behavior indirectly through self-efficacy and its linkage to intentions. Outcome control moderated self-efficacy/intention relations only in Study 2, and the pattern of moderation was contrary to expectations. Implications for further inquiry and practice with job seekers are discussed. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  2. Influence of Social Cognitive and Ethnic Variables on Academic Goals of Underrepresented Students in Science and Engineering: A Multiple-Groups Analysis

    PubMed Central

    Byars-Winston, Angela; Estrada, Yannine; Howard, Christina; Davis, Dalelia; Zalapa, Juan

    2010-01-01

    This study investigated the academic interests and goals of 223 African American, Latino/a, Southeast Asian, and Native American undergraduate students in two groups: biological science and engineering (S/E) majors. Using social cognitive career theory (Lent, Brown, & Hackett, 1994), we examined the relationships of social cognitive variables (math/science academic self-efficacy, math/science outcome expectations), along with the influence of ethnic variables (ethnic identity, other-group orientation) and perceptions of campus climate to their math/science interests and goal commitment to earn an S/E degree. Path analysis revealed that the hypothesized model provided good overall fit to the data, revealing significant relationships from outcome expectations to interests and to goals. Paths from academic self-efficacy to S/E goals and from interests to S/E goals varied for students in engineering and biological science. For both groups, other-group orientation was positively related to self-efficacy and support was found for an efficacy-mediated relationship between perceived campus climate and goals. Theoretical and practical implications of the study’s findings are considered as well as future research directions. PMID:20495610

  3. A comparison between an in vitro method to determine carbohydrate digestion rate and the glycemic response in young men.

    PubMed

    Araya, H; Contreras, P; Alviña, M; Vera, G; Pak, N

    2002-08-01

    This study examines the relationship between the results of in vitro determinations of carbohydrate digestion rates and the glycemic index. Ten healthy non smoking men, aged between 21 and 24-y-old, were selected to participate in the study. Six different meals with similar levels of carbohydrates were assayed at breakfast in ten subjects and blood samples were obtained at 0, 15, 30, 60 and 120 min to determine glucose levels. The Englyst's enzymatic method was used in the in vitro study. The six meals were based in cereals (rice or spaghetti); legumes (lentil soup and beans with spaghetti); and potato (potato stew with meat and vegetables). The meals showed different glycemic indices: rice and spaghetti based meals had lower values (mean value 31.4 and 42, respectively); the intermediate values corresponded to lentil soup and the bean dish (49.3, and 76.8 respectively) and the higher glycemic index was shown by the potato based meal (82). A significant correlation was observed when the ratio of rapid carbohydrate digestion rate and the lente carbohydrate digestion rate was correlated with the glycemic index of the meals, but not when only the rapid carbohydrate digestion rate was considered. These results demonstrate a useful, simple and inexpensive method to estimate the biological response of high carbohydrate meals.

  4. Rapid carbohydrate digestion rate produced lesser short-term satiety in obese preschool children.

    PubMed

    Alviña, M; Araya, H

    2004-04-01

    To examine whether high carbohydrate meals with different carbohydrate digestion rates have an effect on the short-term satiety in normal and obese preschool children. In total, 48 children of both gender, 24 normal and 24 obese, according to body mass index, aged between 3 and 6 y, were selected from children who were attending to a day-care center where they consumed three meals in the day. Rapid (potato-based meal) and lente (spaghetti-based meal) carbohydrate digestion rate meal were given at lunch, matching energy intake, carbohydrate, protein and fat levels, and then the preschool children's energy intake at the subsequent mealtime was observed. In this last mealtime, the children received varied types of high-acceptability foods in higher quantities than the normal serving. At lunch, a significant higher energy intake, lesser satiation, was observed in both groups, normal-weight and obese children, when they consumed the potato-based meal. In the subsequent mealtime, a significant effect of carbohydrate digestion rate was demonstrated, but only in obese preschool children, being higher in the meal with rapid digestion rate carbohydrates. Rapid carbohydrate digestion rate meal produced a significative lesser satiation in normal-weight and obese children. However, only in obese children a significant lesser satiety was observed after consumption of the rapid carbohydrate digestion rate meal, indicating a decreased capacity of energy regulation in obese children. The finding of the present work could provide dietary strategies required for decreasing prevalence in overweight and obesity in preschool children.

  5. Carbohydrate digestibility and metabolic effects.

    PubMed

    Wong, Julia M W; Jenkins, David J A

    2007-11-01

    There is a history of interest in the metabolic effects of alterations in small intestinal digestion and colonic fermentation of carbohydrate. It is believed that the rate of digestion of carbohydrate determines the place and form in which carbohydrate is absorbed. Slowly absorbed or lente carbohydrate sources may reduce postprandial glucose surges and the need for insulin with important implications for lowering coronary heart disease risk and reducing diabetes incidence. Carbohydrates that are not digested in the small intestine will enter the colon, and those that are fermentable will be salvaged as short-chain fatty acids in the colon and at the same time may stimulate colonic microflora, such as bifidobacteria. This process may have metabolic effects in the gut and throughout the host, possibly related to short-chain fatty acid products, although these effects are less well documented. One important aspect of colonic fermentation is the stimulation of certain populations of the colonic microflora, which may assist in the biotransformation of bioactive food components including the cleaving of plant phenolics from their glycone to produce the more rapidly absorbed aglycone. However, human studies have been limited. Therefore, further studies are required to explore these important aspects of metabolism related to the rate of carbohydrate absorption and fermentation and their implications in health and disease.

  6. Bioinformatics Identification of Drug Resistance-Associated Gene Pairs in Mycobacterium tuberculosis.

    PubMed

    Cui, Ze-Jia; Yang, Qing-Yong; Zhang, Hong-Yu; Zhu, Qiang; Zhang, Qing-Ye

    2016-08-27

    Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis (Mtb). Due to the extensive use of anti-tuberculosis drugs and the development of mutations, the emergence and spread of multidrug-resistant tuberculosis is recognized as one of the most dangerous threats to global tuberculosis control. Some single mutations have been identified to be significantly linked with drug resistance. However, the prior research did not take gene-gene interactions into account, and the emergence of transmissible drug resistance is connected with multiple genetic mutations. In this study we use the bioinformatics software GBOOST (The Hong Kong University, Clear Water Bay, Kowloon, Hong Kong, China) to calculate the interactions of Single Nucleotide Polymorphism (SNP) pairs and identify gene pairs associated with drug resistance. A large part of the non-synonymous mutations in the drug target genes that were included in the screened gene pairs were confirmed by previous reports, which lent sound solid credits to the effectiveness of our method. Notably, most of the identified gene pairs containing drug targets also comprise Pro-Pro-Glu (PPE) family proteins, suggesting that PPE family proteins play important roles in the drug resistance of Mtb. Therefore, this study provides deeper insights into the mechanisms underlying anti-tuberculosis drug resistance, and the present method is useful for exploring the drug resistance mechanisms for other microorganisms.

  7. ANALYSIS OF SULFONATES IN AQUEOUS SAMPLES BY ION-PAIR LC/ESI-MS/MS WITH IN-SOURCE CID FOR ADDUCT PEAK ELIMINATION

    SciTech Connect

    OUYANG,S.; VAIRAVAMURTHY,M.A.

    1999-06-13

    Determination of low-molecular-weight organic sulfonates (e.g. taurine and cysteic acid) in aqueous solutions is important in many applications of biological, environmental and pharmaceutical sciences. These compounds are difficult to be determined by commonly used reversed-phase liquid chromatographic separation combined with UV-Visible detection because of their high solubility and the lack chromophoric moieties. Here the authors report a method combining ion-pair liquid chromatography and electrospray ionization tandem mass spectrometry (IPLC/ESI-MS/MS)for determining sulfonates. The ability of low-molecular-weight sulfonates to form ion-pairs with quaternary ammonium cations in aqueous solutions allowed LC separation with a C{sub 18} column. Detection of the sulfonates was accomplished with ESI-MS that lends a universal mode of mass detection for polar, water soluble compounds. An in-source collision induced dissociation (CID) was applied to eliminate the adduct peaks in mass spectra. Characteristic marker ions showed in the second stage mass spectra lent a method for identifying sulfonates.

  8. Corrosion of structural materials by lead-based reactor coolants.

    SciTech Connect

    Abraham, D. P.; Leibowitz, L.; Maroni, V. A.; McDeavitt, S. M.; Raraz, A. G.

    2000-11-16

    Advanced nuclear reactor design has, in recent years, focused increasingly on the use of heavy-liquid-metal coolants, such as lead and lead-bismuth eutectic. Similarly, programs on accelerator-based transmutation systems have also considered the use of such coolants. Russian experience with heavy-metal coolants for nuclear reactors has lent credence to the validity of this approach. Of significant concern is the compatibility of structural materials with these coolants. We have used a thermal convection-based test method to allow exposure of candidate materials to molten lead and lead-bismuth flowing under a temperature gradient. The gradient was deemed essential in evaluating the behavior of the test materials in that should preferential dissolution of components of the test material occur we would expect dissolution in the hotter regions and deposition in the colder regions, thus promoting material transport. Results from the interactions of a Si-rich mild steel alloy, AISI S5, and a ferritic-martensitic stainless steel, HT-9, with the molten lead-bismuth are presented.

  9. [Use of health professional cards by general practice locums: frequency and difficulties].

    PubMed

    Godin, Audrey; Renouf, Vincent; Raginel, Thibaut

    2015-01-01

    Health professional cards are used for electronic production and transmission of medical reimbursement requests. These cards are personal and cannot be lent, including to locums. However, general practice locums often report using the cards of the practitioners they replace. The aim of this study was to assess the use of general practice locum's own professional cards for patient reimbursements in 2013. A retrospective survey by computerized questionnaire was conducted in 2014 in Lower-Normandy among general practice locums. Data were collected on their possession, knowledge,frequency and difficulties using their own cards in 2013. All locums were familiar with health professional cards, but 71.9% did not know about health professional trainee cards. 71.9% of respondents had a card in 2013 and only 26.1% of them had already used the card. 78.1% of respondents thought they could use the card of the practitioner that they replaced' The main difficulties encountered when using health professional cards were the failure of general practitioners to ask locums to use their own cards, problems with software configuration and card installation, and a poor understanding of the purpose of the card. Locums in Lower Normandy in 2013 rarely used their own cards when they have one. Better information concerning use of the cars is required for locums.

  10. Geometric issues in reverse osmosis: numerical simulation and experimentation.

    PubMed

    Srivathsan, G; Sparrow, Ephraim; Gorman, John

    2014-01-01

    This investigation is a synergistic combination of laboratory experimentation and numerical simulation to quantify the practical impact of geometric imperfections in the flow channels of a reverse osmosis (RO) system. To this end, carefully executed experiments are performed to quantify the fluid flow in a system containing feed spacers which are embedded in the RO membrane. In a complementary activity, numerical simulations were performed both for an ideal geometric situation (without embedments) and the actual geometric configuration including the embedments. It was found that the presence of unaccounted embedments affected the pressure drop predictions for the system by 14-19%. When account was taken of the embedments, the simulation results were found to be virtually coincident with the experimental results. This outcome suggests that deviations between experimental and simulation results encountered in the literature might well have been due to geometrical deviations of the type investigated here. The numerical simulation of the feedwater fluid flow was based on the often-used but unverified assumption that the velocity field experiences the geometric periodicity of the feed spacer. This assumption was lent support by results from a non-periodic simulation model and by the excellent agreement between the numerically based predictions and the experimental data.

  11. The metaphor of epigenesis: Kant, Blumenbach and Herder.

    PubMed

    Helbig, Daniela; Nassar, Dalia

    2016-08-01

    Over the last few decades, the meaning of the scientific theory of epigenesis and its significance for Kant's critical philosophy have become increasingly central questions. Most recently, scholars have argued that epigenesis is a key factor in the development of Kant's understanding of reason as self-grounding and self-generating. Building on this work, our claim is that Kant appealed to not just any epigenetic theory, but specifically Johann Friedrich Blumenbach's account of generation, and that this appeal must be understood not only in terms of self-organization, but also in terms of the demarcation of a specific domain of inquiry: for Blumenbach, the study of life; for Kant, the study of reason. We argue that Kant adopted this specific epigenetic model as a result of his dispute with Herder regarding the independence of reason from nature. Blumenbach's conception of epigenesis and his separation of a domain of the living from the non-living lent Kant the tools to demarcate metaphysics, and to guard reason against Herder's attempts to naturalize it.

  12. Ethical considerations of mobile phone use by patients in KwaZulu-Natal: Obstacles for mHealth?

    PubMed Central

    Mars, Maurice

    2014-01-01

    Abstract Background mHealth has the potential to facilitate telemedicine services, particularly in the developing world. Concern has been expressed about the confidentiality of health information that is relayed by mobile phone. Aim We examined the habits and practices of mobile phone use by patients in KwaZulu-Natal, South Africa. Methods We conducted a descriptive survey of two patient populations: 137 urban patients attending private practitioners and 139 patients in remote rural areas attending outpatient departments in Government-funded hospitals. The questionnaire covered several domains: demographics, mobile phone use, privacy and confidentiality and future use for health-related matters. Results Two hundred and seventy-six patients completed the questionnaire. We found that a third of our participants shared their mobile phone with others, 24% lent their phone to others and more than half received health-related messages for other people. Mobile phone theft was common, as was number changing. Thirty-eight percent of the people were not able to afford airtime for more than a week in the past year and 22% of rural patients were unable to keep their phone charged. Mobile phone signal coverage was significantly worse in the rural areas than in urban areas. Conclusion This study highlights the legal and ethical ramifications that these practices and findings will have on mHealth programmes in our setting. Healthcare providers and regulators will need to consider how patients use and manage their mobile phones when developing services and regulations. PMID:26245406

  13. Job characteristics, recovery experiences and occupational well-being: testing cross-lagged relationships across 1 year.

    PubMed

    Kinnunen, Ulla; Feldt, Taru

    2013-12-01

    The aim of the present study conducted among 274 Finnish employees was to examine the relationships between job characteristics, recovery experiences and occupational well-being across 1 year. We hypothesized that these relationships would follow normal causation, that is, job characteristics at T1 predict recovery experiences (detachment, relaxation, mastery and control at off-job time) and well-being (fatigue at work and work engagement) at T2, and recovery experiences at T1 predict well-being at T2. The structural equation modelling analyses lent support to the hypothesized normal causation model compared with the reversed causation and reciprocal models. However, only the longitudinal relationships between job characteristics and recovery experiences were significant. More specifically, high job demands at T1 predicted poor detachment, relaxation and control during off-job time at T2; and high job resources at T1 predicted high mastery experiences in off-job time at T2. Thus, our study showed that job demands in particular inhibited recovery experiences in the long term, but this was not reflected in employee well-being across 1 year. Copyright © 2013 John Wiley & Sons, Ltd.

  14. Impact of caloric and dietary restriction regimens on markers of health and longevity in humans and animals: a summary of available findings

    PubMed Central

    2011-01-01

    Considerable interest has been shown in the ability of caloric restriction (CR) to improve multiple parameters of health and to extend lifespan. CR is the reduction of caloric intake - typically by 20 - 40% of ad libitum consumption - while maintaining adequate nutrient intake. Several alternatives to CR exist. CR combined with exercise (CE) consists of both decreased caloric intake and increased caloric expenditure. Alternate-day fasting (ADF) consists of two interchanging days; one day, subjects may consume food ad libitum (sometimes equaling twice the normal intake); on the other day, food is reduced or withheld altogether. Dietary restriction (DR) - restriction of one or more components of intake (typically macronutrients) with minimal to no reduction in total caloric intake - is another alternative to CR. Many religions incorporate one or more forms of food restriction. The following religious fasting periods are featured in this review: 1) Islamic Ramadan; 2) the three principal fasting periods of Greek Orthodox Christianity (Nativity, Lent, and the Assumption); and 3) the Biblical-based Daniel Fast. This review provides a summary of the current state of knowledge related to CR and DR. A specific section is provided that illustrates related work pertaining to religious forms of food restriction. Where available, studies involving both humans and animals are presented. The review includes suggestions for future research pertaining to the topics of discussion. PMID:21981968

  15. [Natural history and eighteenth-century ideas regarding generation and heredity: Buffon and Bonnet].

    PubMed

    Castañeda, L A

    1995-01-01

    The intellectual course of natural history reveals three conceptual approaches. The first was the taxonomic point of view, where naturalists worked to name and classify the living beings created by God. The second approach was provided by the eighteenth century's philosophical doctrine of mechanism, which lent natural history its method of endeavoring to comprehend the workings of organisms, inasmuch as the world "ran". Calling into question the adequacy of prior message, the third approach argued that living things display characteristics quite distinct from those of non-living matter, making it necessary to understand processes rather than simply decompose phenomena to then analyze them. This inadequacy became apparent at the moment when ideas of generation and heredity ascribed a reproductive history to living things, a history where the act of one fellow creature being formed by another plays an important role in coming to understand the workings of life. The paper analyzes these conceptual approaches from the perspective of Buffon's and Bonnet's ideas on reproduction and heredity, which represented opposite schools of thought: epigenesis and preformation.

  16. Compression of thick laminated composite beams with initial impact-like damage

    NASA Technical Reports Server (NTRS)

    Breivik, N. L.; Guerdal, Z.; Griffin, O. H., Jr.

    1992-01-01

    While the study of compression after impact of laminated composites has been under consideration for many years, the complexity of the damage initiated by low velocity impact has not lent itself to simple predictive models for compression strength. The damage modes due to non-penetrating, low velocity impact by large diameter objects can be simulated using quasi-static three-point bending. The resulting damage modes are less coupled and more easily characterized than actual impact damage modes. This study includes the compression testing of specimens with well documented initial damage states obtained from three-point bend testing. Compression strengths and failure modes were obtained for quasi-isotropic stacking sequences from 0.24 to 1.1 inches thick with both grouped and interspersed ply stacking. Initial damage prior to compression testing was divided into four classifications based on the type, extent, and location of the damage. These classifications are multiple through-thickness delaminations, isolated delamination, damage near the surface, and matrix cracks. Specimens from each classification were compared to specimens tested without initial damage in order to determine the effects of the initial damage on the final compression strength and failure modes. A finite element analysis was used to aid in the understanding and explanation of the experimental results.

  17. A human factors systems approach to understanding team-based primary care: a qualitative analysis.

    PubMed

    Mundt, Marlon P; Swedlund, Matthew P

    2016-12-01

    Research shows that high-functioning teams improve patient outcomes in primary care. However, there is no consensus on a conceptual model of team-based primary care that can be used to guide measurement and performance evaluation of teams. To qualitatively understand whether the Systems Engineering Initiative for Patient Safety (SEIPS) model could serve as a framework for creating and evaluating team-based primary care. We evaluated qualitative interview data from 19 clinicians and staff members from 6 primary care clinics associated with a large Midwestern university. All health care clinicians and staff in the study clinics completed a survey of their communication connections to team members. Social network analysis identified key informants for interviews by selecting the respondents with the highest frequency of communication ties as reported by their teammates. Semi-structured interviews focused on communication patterns, team climate and teamwork. Themes derived from the interviews lent support to the SEIPS model components, such as the work system (Team, Tools and Technology, Physical Environment, Tasks and Organization), team processes and team outcomes. Our qualitative data support the SEIPS model as a promising conceptual framework for creating and evaluating primary care teams. Future studies of team-based care may benefit from using the SEIPS model to shift clinical practice to high functioning team-based primary care. © The Author 2016. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  18. The measurement of patellar alignment in patellofemoral pain syndrome: are we confusing assumptions with evidence?

    PubMed

    Wilson, Tony

    2007-06-01

    Patellofemoral pain syndrome is one of the most common orthopaedic complaints presenting to physical therapists. Although its etiology is uncertain, the cause is most often considered to be malalignment or lateral tracking of the patella. Consequently, measurement of patellar alignment has come to be accepted as an integral part of the examination of patellofemoral pain syndrome. Various measurement techniques exist, both clinical and radiological, and these have been frequently used in the diagnosis and treatment of the condition. As a corollary, the widespread use of such measurements has also lent weight to the theory that patellar malalignment is one of the primary causes of patellofemorai pain syndrome. However, an analysis of the literature reveals that the vast majority of these measurement procedures lack the appropriate scientific qualities to be considered acceptable measurement tools, including questionable reliability and validity, and an absence of appropriate normative data and a gold standard. This paper assesses the evidence for the usefulness of the most commonly used measures of patellar alignment and concludes that many of the beliefs of the clinical community with regard to the existence and measurement of patellar malalignment in patellofemoral pain syndrome may be based largely on assumptions and not on evidence.

  19. Investigation of social cognitive career theory for minority recruitment in school psychology.

    PubMed

    Bocanegra, Joel O; Gubi, Aaron A; Cappaert, Kevin J

    2016-06-01

    School psychology trainers have historically struggled to adequately increase the number of professionals from diverse backgrounds. An increase in diverse providers is important in meeting the needs of a burgeoning racial/ethnic minority student population. Previous research suggests that minority undergraduate psychology students have less knowledge and exposure to school psychology than for counseling and clinical psychology, and that students with greater exposure or knowledge of school psychology reported significantly greater choice intentions for school psychology. The purpose of this study is to test the applicability of the Social Cognitive Career Theory (SCCT; Lent, Brown, & Hackett, 1994) in explaining minority undergraduate psychology students' choice intentions for school psychology. This study is an analysis of existing data and is based on a national sample of 283 minority undergraduate psychology students. All instruments used in this study were found to have internal consistency ranging from .83 to .91. Students' learning experiences, self-efficacy, outcome expectations, and choice intentions for school psychology were evaluated by way of a mediator analysis. Results from a path analysis suggest that outcome expectations mediated the relationship between exposure and choice intentions for school psychology. Implications for minority recruitment practices are discussed. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  20. Paperless anesthesia: uses and abuses of these data.

    PubMed

    Anderson, Brian J; Merry, Alan F

    2015-12-01

    Demonstrably accurate records facilitate clinical decision making, improve patient safety, provide better defense against frivolous lawsuits, and enable better medical policy decisions. Anesthesia Information Management Systems (AIMS) have the potential to improve on the accuracy and reliability of handwritten records. Interfaces with electronic recording systems within the hospital or wider community allow correlation of anesthesia relevant data with biochemistry laboratory results, billing sections, radiological units, pharmacy, earlier patient records, and other systems. Electronic storage of large and accurate datasets has lent itself to quality assurance, enhancement of patient safety, research, cost containment, scheduling, anesthesia training initiatives, and has even stimulated organizational change. The time for record making may be increased by AIMS, but in some cases has been reduced. The question of impact on vigilance is not entirely settled, but substantial negative effects seem to be unlikely. The usefulness of these large databases depends on the accuracy of data and they may be incorrect or incomplete. Consequent biases are threats to the validity of research results. Data mining of biomedical databases makes it easier for individuals with political, social, or economic agendas to generate misleading research findings for the purpose of manipulating public opinion and swaying policymakers. There remains a fear that accessibility of data may have undesirable regulatory or legal consequences. Increasing regulation of treatment options during the perioperative period through regulated policies could reduce autonomy for clinicians. These fears are as yet unsubstantiated. © 2015 John Wiley & Sons Ltd.

  1. Manipulating In-House Designed Drug Databases For The Prediction of pH-Dependent Aqueous Drug Solubility

    PubMed Central

    D’Souza, Malcolm J.; AlAbed, Ghada J.; Earley, Melissa; Roberts, Natalia; Gerges, Fady J.

    2014-01-01

    Chemical, pharmacokinetic, and pharmacodynamics properties are available in the package inserts of every Food and Drug Administration (FDA) approved prescription drug, including all available chemotherapy drugs. These inserts follow a specific format imposed by the FDA. Whether chemotherapy drugs are administered via the parenteral route or alimentary tract, a significant factor affecting their bioavailability, elimination and consequently the drug’s effectiveness and potency, is its state of aqueous solubility. Water solubility has always lent itself poorly to the different predictive and experimental measures employed in the determination of a useful quantitative assessment. In this project, we first built a chemical structure based searchable database for 85 FDA approved chemotherapy drugs and then used Bio-Rad’s KnowItAll® Informatics suite to focus on the drugs pH-dependent water solubility prediction. We compared the predicted values for water solubility to the available values reported in the drug inserts, testing the practical utility and the predictive ability of our model in reporting such a clinically relevant, underreported pharmacokinetic parameter. A relational cancer drug database (MySQL) was created to further facilitate analysis and/or prediction of a chemotherapy compound’s missing pharmacokinetic properties. PMID:24478935

  2. Predicting the math/science career goals of low-income prospective first-generation college students.

    PubMed

    Garriott, Patton O; Flores, Lisa Y; Martens, Matthew P

    2013-04-01

    The present study used social cognitive career theory (SCCT; Lent, Brown, & Hackett, 1994) to predict the math/science goal intentions of a sample of low-income prospective first-generation college students (N = 305). Structural equation modeling was used to test a model depicting relationships between contextual (i.e., social class, learning experiences, proximal supports and barriers) and person-cognitive (i.e., self-efficacy, outcome expectations, interests, goals) variables as hypothesized in SCCT and based on previous literature on low-income first-generation college students. Results indicated that the hypothesized model provided the best representation of the data. All paths in the model were statistically significant, with the exceptions of paths from self-efficacy to goals, outcome expectations to interests, and perceived barriers to self-efficacy. Bootstrapping procedures revealed that the relationships between social class, self-efficacy, and outcome expectations were mediated through learning experiences. Furthermore, the relationship between social supports and goals was mediated by self-efficacy and interests and the relationships between self-efficacy, outcome expectations, and goals were mediated by interests. Contrary to hypotheses, the relationship between barriers and goals was not mediated by self-efficacy and interests. The hypothesis that proximal contextual supports and barriers would moderate the relationship between interests and goals was not supported. The final model explained 66% and 55% of the variance in math/science interests and goals, respectively. Implications for future research and practice are discussed.

  3. Sci—Thur AM: YIS - 11: Estimation of Bladder-Wall Cumulative Dose in Multi-Fraction Image-Based Gynaecological Brachytherapy Using Deformable Point Set Registration

    SciTech Connect

    Zakariaee, R; Brown, C J; Hamarneh, G; Parsons, C A; Spadinger, I

    2014-08-15

    Dosimetric parameters based on dose-volume histograms (DVH) of contoured structures are routinely used to evaluate dose delivered to target structures and organs at risk. However, the DVH provides no information on the spatial distribution of the dose in situations of repeated fractions with changes in organ shape or size. The aim of this research was to develop methods to more accurately determine geometrically localized, cumulative dose to the bladder wall in intracavitary brachytherapy for cervical cancer. The CT scans and treatment plans of 20 cervical cancer patients were used. Each patient was treated with five high-dose-rate (HDR) brachytherapy fractions of 600cGy prescribed dose. The bladder inner and outer surfaces were delineated using MIM Maestro software (MIM Software Inc.) and were imported into MATLAB (MathWorks) as 3-dimensional point clouds constituting the “bladder wall”. A point-set registration toolbox for MATLAB, Coherent Point Drift (CPD), was used to non-rigidly transform the bladder-wall points from four of the fractions to the coordinate system of the remaining (reference) fraction, which was chosen to be the emptiest bladder for each patient. The doses were accumulated on the reference fraction and new cumulative dosimetric parameters were calculated. The LENT-SOMA toxicity scores of these patients were studied against the cumulative dose parameters. Based on this study, there was no significant correlation between the toxicity scores and the determined cumulative dose parameters.

  4. Neuroimaging of Fear-Associated Learning.

    PubMed

    Greco, John A; Liberzon, Israel

    2016-01-01

    Fear conditioning has been commonly used as a model of emotional learning in animals and, with the introduction of functional neuroimaging techniques, has proven useful in establishing the neurocircuitry of emotional learning in humans. Studies of fear acquisition suggest that regions such as amygdala, insula, anterior cingulate cortex, and hippocampus play an important role in acquisition of fear, whereas studies of fear extinction suggest that the amygdala is also crucial for safety learning. Extinction retention testing points to the ventromedial prefrontal cortex as an essential region in the recall of the safety trace, and explicit learning of fear and safety associations recruits additional cortical and subcortical regions. Importantly, many of these findings have implications in our understanding of the pathophysiology of psychiatric disease. Recent studies using clinical populations have lent insight into the changes in regional activity in specific disorders, and treatment studies have shown how pharmaceutical and other therapeutic interventions modulate brain activation during emotional learning. Finally, research investigating individual differences in neurotransmitter receptor genotypes has highlighted the contribution of these systems in fear-associated learning.

  5. Pellet pestle homogenization of agarose gel slices at 45 degrees C for deoxyribonucleic acid extraction.

    PubMed

    Kurien, B T; Kaufman, K M; Harley, J B; Scofield, R H

    2001-09-15

    A simple method for extracting DNA from agarose gel slices is described. The extraction is rapid and does not involve harsh chemicals or sophisticated equipment. The method involves homogenization of the excised gel slice (in Tris-EDTA buffer), containing the DNA fragment of interest, at 45 degrees C in a microcentrifuge tube with a Kontes pellet pestle for 1 min. The "homogenate" is then centrifuged for 30 s and the supernatant is saved. The "homogenized" agarose is extracted one more time and the supernatant obtained is combined with the previous supernatant. The DNA extracted using this method lent itself to restriction enzyme analysis, ligation, transformation, and expression of functional protein in bacteria. This method was found to be applicable with 0.8, 1.0, and 2.0% agarose gels. DNA fragments varying from 23 to 0.4 kb were extracted using this procedure and a yield ranging from 40 to 90% was obtained. The yield was higher for fragments 2.0 kb and higher (70-90%). This range of efficiency was maintained when the starting material was kept between 10 and 300 ng. The heat step was found to be critical since homogenization at room temperature failed to yield any DNA. Extracting DNA with our method elicited an increased yield (up to twofold) compared with that extracted with a commercial kit. Also, the number of transformants obtained using the DNA extracted with our method was at least twice that obtained using the DNA extracted with the commercial kit.

  6. Anatomy's use of unclaimed bodies: reasons against continued dependence on an ethically dubious practice.

    PubMed

    Jones, D Gareth; Whitaker, Maja I

    2012-03-01

    The use of unclaimed bodies has been one of the distinguishing features of the anatomy profession since the passing of nineteenth century legislation aimed at solving the problem of grave robbing. Only in more recent years has the use of bequeathed bodies supplanted dependence upon unclaimed bodies in many (but not all) countries. We argue that this dependence has opened the profession to a range of questionable ethical practices. Starting with contraventions of the early Anatomy Acts, we trace the manner in which the legitimacy of using unclaimed bodies has exposed vulnerable groups to dissection without their consent. These groups have included the impoverished, the mentally ill, African Americans, slaves, and stigmatized groups during the Nazi era. Unfortunately, ethical constraints have not been imposed on the use of unclaimed bodies. The major public plastination exhibitions of recent years invite us to revisit these issues, even though some like Body Worlds claim to use bequeathed bodies. The widespread use of unclaimed bodies in institutional settings has lent to these public exhibitions a modicum of legitimacy that is needed even when donated bodies are employed. This is because the notion of donation has changed as demonstrated by consideration of the principles of beneficence and non-maleficence. We conclude that anatomists should cease using unclaimed bodies. Difficult as this will be in some cultures, the challenge for anatomists is to establish relationships of trust with their local communities and show how body donation can assist both the community and the profession.

  7. Electrisation

    PubMed Central

    Chaibdraa, A.; Medjellekh, M.S.; Bentakouk, M.C.

    2009-01-01

    Summary La qualité de la prise en charge en urgence des patients atteints d'accidents d'électrisation dépend du degré de compréhension des données physiopathologiques à l'origine des nombreuses manifestations cliniques, dominées par la mort subite. La connaissance des rôles respectifs des différentes caractéristiques de l'électricité (les ampères tuent, les volts brûlent, le risque potentiellement élevé de traumatisme associé), de l'électrothermie et des mécanismes à l'échelon cellulaire a permis de mieux appréhender son extrême gravité. Les conséquences fonctionnelles, esthétiques et psychologiques, avec de lourdes séquelles, expliquent le caractère multidisciplinaire de la prise en charge au long cours. Face à une morbidité importante, la prévention est fondamentale, en particulier pour les professions exposées et pour ce qui concerne les accidents domestiques chez l'enfant. PMID:21991147

  8. Social-cognitive predictors of vocational outcomes in transition youth with epilepsy: Application of social cognitive career theory.

    PubMed

    Sung, Connie; Connor, Annemarie

    2017-08-01

    This study examined the utility of social-cognitive career theory (SCCT; Lent, Brown, & Hackett, 1994) as a framework to investigate career self-efficacy, outcome expectations, goals, and contextual supports and barriers as predictors of choice actions among transition-age individuals with epilepsy. Moreover, these SCCT constructs are offered as an operational definition of work participation in this population. Using a quantitative descriptive research design and hierarchical regression analysis (HRA), 90 transition-age individuals with epilepsy, age 18-25, were recruited from affiliates of the Epilepsy Foundation and invited to complete an online survey comprised of a series of self-report social-cognitive measures. The HRA findings indicated that self-efficacy, outcome expectations, and environmental supports were significant predictors of work participation in youth and young adults with epilepsy. The final model accounted for 58% of the variance in work participation, which is considered a large effect size. The research findings provide support for the use of the SCCT framework to identify predictors of work participation and to provide guidance for designing customized vocational rehabilitation services and career development interventions for individuals with epilepsy in the transition from adolescence to adulthood. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  9. Molecular biology of seed storage proteins and lectins

    SciTech Connect

    Shannon, L.M.; Chrispeels, M.J.

    1986-01-01

    The seeds of many plants contain abundant storage protein and lectin which have been the subject of biochemical investigations for over a hundred years. Because these proteins represent abundant gene products translated from abundant messages, they were among the first plant proteins to which the techniques of molecular biology were applied. Many of the proteins have now been purified and characterized and their amino acid sequences have been determined; some have been crystallized and their 3-dimensional structure is known. Studies of their biosynthesis, transport and accumulation in protein bodies have lead to a greater understanding of the dynamics of plant cell organelles. Seed storage proteins and lectins are encoded by small gene families whose members show considerable homology and appear to have been conserved in evolution. The expression of these genes is highly regulated in time (development) and space (tissue). The recent discovery that other plant organs synthesize lectins, or lectin-like proteins which are closely related to the seed lectins, has lent additional support to the search for a function for these intriguing proteins; this finding also indicates that different members of the gene family are expressed in different tissues. Individual papers were processed separately for the data base.

  10. Social cognitive predictors of academic and life satisfaction: Measurement and structural equivalence across three racial/ethnic groups.

    PubMed

    Sheu, Hung-Bin; Mejia, Araceli; Rigali-Oiler, Marybeth; Primé, Dominic R; Chong, Shiqin Stephanie

    2016-07-01

    Data of 306 Caucasian American, 284 Asian American, and 259 Latino/a American college students were analyzed in this study to test a modified version of Lent and Brown's (2006, 2008) satisfaction model in the academic context. In addition to the full set of variables hypothesized in the original model, the modified academic satisfaction model also included independent and interdependent self-construals to represent one's cultural orientations. Comparisons between the hypothesized model and 2 alternative models showed that direct paths from extraversion and emotional stability added significantly to the predictions of academic satisfaction and life satisfaction for all 3 racial/ethnic groups while those from independent and interdependent self-construals also had the same effects for Latino/a American students. The hypothesized model offered excellent fit to the data of all 3 racial/ethnic groups. Consistent with theoretical prediction, academic supports, self-efficacy, outcome expectations, or goal progress formed pathways that mediated the relations of personality traits and self-construals to academic satisfaction or life satisfaction across 3 groups. Although full measurement equivalence (configural invariance and metric invariance) was observed, 4 structural paths and 16 indirect effects differed significantly by race/ethnicity. Most of these differences in structural paths and indirect effects occurred between Caucasian Americans and Asian Americans. On balance, findings of the study provided evidence for the cross-racial/ethnic validity of the modified academic satisfaction model while identifying racial/ethnic differences that might have useful clinical implications. (PsycINFO Database Record

  11. Eltgol Acutelly Improves Airway Clearance and Reduces Static Pulmonary Volumes in Adult Cystic Fibrosis Patients

    PubMed Central

    Guimarães, Fernando Silva; Lopes, Agnaldo José; Moço, Vanessa Joaquim Ribeiro; Cavalcanti de Souza, Felipe; Silveira de Menezes, Sara Lúcia

    2014-01-01

    Chest physical therapy techniques are essential in order to reduce the frequency of recurrent pulmonary infections that progressively affect lung function in cystic fibrosis patients. Recently, ELTGOL (L’Expiration Lente Totale Glotte Ouverte en décubitus Latéral) emerged as an inexpensive and easy to perform therapeutic option. The aim of this study was to compare the acute effects of ELTGOL and the Flutter valve in stable adult patients with cystic fibrosis. [Subjects and Methods] This was a randomized, crossover study with a sample of cystic fibrosis outpatients. The subjects underwent two protocols (Flutter Valve and ELTGOL interventions, referred to as ELTGOL and FLUTTER) in a randomized order with a one-week washout interval between them. The main outcomes were pulmonary function variables and expectorated sputum dry weight. [Results] ELTGOL cleared 0.34 g more of secretions than FLUTTER (95% CI 0.11 to 0.57). When comparing the physiological effects of ELTGOL and FLUTTER, the first was superior in improving airway resistance (−0.51 cmH2O/L/s; 95% CI −0.88 to −0.14) and airway conductance (0.016 L/s/cmH2O; 95% CI 0.008 to 0.023). [Conclusion] ELTGOL promoted higher secretion removal and improvement in airway resistance and conductance than the Flutter valve. These techniques were equivalent in reducing the pulmonary hyperinflation and air trapping in cystic fibrosis patients. PMID:25013273

  12. First-principles search for potential high temperature superconductors in the Mg-B-A (A=alkaline metal) system with high boron content

    NASA Astrophysics Data System (ADS)

    Chepulskyy, Roman; Mazin, Igor; Curtarolo, Stefano

    2008-03-01

    Possible superconductivity at 50K was recently reported [1] in the Mg-B-A (A=Cs, Rb, Ba) system. Although attempts to reproduce this finding have been unsuccessful so far [2], if a stable or metastable phase could be found by a first principle search similar to that in Ref. 3, this would have lent credibility to the experimental finding [1] and outline possible further directions. The results of Ref. 1 suggest that (a) the superconducting phase is not similar to MgB2 (B site has cubic or similarly high symmetry) and (b) boron content is higher than in MgB2. We report first-principles study of the thermodynamics of alkali and alkaline earth doping in the boron- rich part of the Mg-B phase diagram (MgBn with n>2), searching for a phase that could explain the results of Ref. [1]. [1] A.V. Palnichenko et al., JETP Letters 86, 272 (2007). [2] R K Singh et al http://arxiv.org/abs/0709.4001v1. [3] S. Curtarolo et al, Calphad 29, 163 (2005).

  13. Insights into how nucleotide supplements enhance the peroxidase-mimicking DNAzyme activity of the G-quadruplex/hemin system

    PubMed Central

    Stefan, Loic; Denat, Franck; Monchaud, David

    2012-01-01

    Since the initial discovery of the catalytic capability of short DNA fragments, this peculiar enzyme-like property (termed DNAzyme) has continued to garner much interest in the scientific community because of the virtually unlimited applications in developing new molecular devices. Alongside the exponential rise in the number of DNAzyme applications in the last past years, the search for convenient ways to improve its overall efficiency has only started to emerge. Credence has been lent to this strategy by the recent demonstration that the quadruplex-based DNAzyme proficiency can be enhanced by ATP supplements. Herein, we have made a further leap along this path, trying first of all to decipher the actual DNAzyme catalytic cycle (to gain insights into the steps ATP may influence), and subsequently investigating in detail the influence of all the parameters that govern the catalytic efficiency. We have extended this study to other nucleotides and quadruplexes, thus demonstrating the versatility and broad applicability of such an approach. The defined exquisitely efficient DNAzyme protocols were exploited to highlight the enticing advantages of this method via a 96-well plate experiment that enables the detection of nanomolar DNA concentrations in real-time with the naked-eye (see movie as Supplementary Data). PMID:22730286

  14. A twice-as-smart synthetic G-quartet: PyroTASQ is both a smart quadruplex ligand and a smart fluorescent probe.

    PubMed

    Laguerre, Aurélien; Stefan, Loic; Larrouy, Manuel; Genest, David; Novotna, Jana; Pirrotta, Marc; Monchaud, David

    2014-09-03

    Recent and unambiguous evidences of the formation of DNA and RNA G-quadruplexes in cells has provided solid support for these structures to be considered as valuable targets in oncology. Beyond this, they have lent further credence to the anticancer strategies relying on small molecules that selectively target these higher-order DNA/RNA architectures, referred to as G-quadruplex ligands. They have also shed bright light on the necessity of designing multitasking ligands, displaying not only enticing quadruplex interacting properties (affinity, structural selectivity) but also additional features that make them usable for detecting quadruplexes in living cells, notably for determining whether, when, and where these structures fold and unfold during the cell cycle and also for better assessing the consequences of their stabilization by external agents. Herein, we report a brand new design of such multitasking ligands, whose structure experiences a quadruplex-promoted conformational switch that triggers not only its quadruplex affinity (i.e., smart ligands, which display high affinity and selectivity for DNA/RNA quadruplexes) but also its fluorescence (i.e., smart probes, which behave as selective light-up fluorescent reporters on the basis of a fluorogenic electron redistribution). The first prototype of such multifunctional ligands, termed PyroTASQ, represents a brand new generation of quadruplex ligands that can be referred to as "twice-as-smart" quadruplex ligands.

  15. The Afya Bora Fellowship: An Innovative Program Focused on Creating an Interprofessional Network of Leaders in Global Health.

    PubMed

    Green, Wendy M; Farquhar, Carey; Mashalla, Yohana

    2017-09-01

    Most current health professions education programs are focused on the development of clinical skills. As a result, they may not address the complex and interconnected nature of global health. Trainees require relevant clinical, programmatic, and leadership skills to meet the challenges of practicing in an increasingly globalized environment. To develop health care leaders within sub-Saharan Africa, the Afya Bora Consortium developed a one-year fellowship for medical doctors and nurses. Fellows from nine institutions in the United States and sub-Saharan Africa participate in 12 learning modules focused on leadership development and program management. Classroom-based training is augmented with an experiential apprenticeship component. Since 2011, 100 fellows have graduated from the program. During their apprenticeships, fellows developed projects beneficial to their development and to host organizations. The program has developed fellows' skills in leadership, lent expertise to local organizations, and built knowledge in local contexts. Most fellows have returned to their countries of origin, thus building local capacity. U.S.-based fellows examine global health challenges from regional perspectives and learn from sub-Saharan African experts and peers. The Consortium provides ongoing support to alumni through career development awards and alumni network engagement with current and past fellow cohorts. The Consortium expanded from its initial network of five countries to six and continues to seek opportunities for geographical and institutional expansion.

  16. From goal motivation to goal progress: the mediating role of coping in the Self-Concordance Model.

    PubMed

    Gaudreau, Patrick; Carraro, Natasha; Miranda, Dave

    2012-01-01

    The present studies examined the mediating role of self-regulatory mechanisms in the relationship between goal motivation and goal progress in the Self-Concordance Model. First, a systematic review, using meta-analytical path analysis, supported the mediating role of effort and action planning in the positive association between autonomous goal motivation and goal progress. Second, results from two additional empirical studies, using structural equation modeling, lent credence to the mediating role of coping in the relationship between goal motivation and goal progress of university students. Autonomous goal motivation was positively associated with task-oriented coping, which predicted greater goal progress during midterm exams (Study 1, N=702) and at the end of the semester in a different sample (Study 2, N=167). Controlled goal motivation was associated with greater disengagement-oriented coping (Study 1 and Study 2) and lesser use of task-oriented coping (Study 2), which reduced goal progress. These results held up after controlling for perceived stress (Study 2). Our findings highlight the importance of coping in the "inception-to-attainment" goal process because autonomous goal motivation indirectly rather than directly predicts goal progress of university students through their usage of task-oriented coping.

  17. Social cognitive predictors of first- and non-first-generation college students' academic and life satisfaction.

    PubMed

    Garriott, Patton O; Hudyma, Aaron; Keene, Chesleigh; Santiago, Dana

    2015-04-01

    The present study tested Lent's (2004) social-cognitive model of normative well-being in a sample (N = 414) of first- and non-first-generation college students. A model depicting relationships between: positive affect, environmental supports, college self-efficacy, college outcome expectations, academic progress, academic satisfaction, and life satisfaction was examined using structural equation modeling. The moderating roles of perceived importance of attending college and intrinsic goal motivation were also explored. Results suggested the hypothesized model provided an adequate fit to the data while hypothesized relationships in the model were partially supported. Environmental supports predicted college self-efficacy, college outcome expectations, and academic satisfaction. Furthermore, college self-efficacy predicted academic progress while college outcome expectations predicted academic satisfaction. Academic satisfaction, but not academic progress predicted life satisfaction. The structural model explained 44% of the variance in academic progress, 56% of the variance in academic satisfaction, and 28% of the variance in life satisfaction. Mediation analyses indicated several significant indirect effects between variables in the model while moderation analyses revealed a 3-way interaction between academic satisfaction, intrinsic motivation for attending college, and first-generation college student status on life satisfaction. Results are discussed in terms of applying the normative model of well-being to promote first- and non-first-generation college students' academic and life satisfaction.

  18. The Incidence of Sixteenth Century Cosmic Models in Modern Texts

    NASA Astrophysics Data System (ADS)

    Maene, S. A.; Best, J. S.; Usher, P. D.

    1999-12-01

    In the sixteenth century, the bounded cosmological models of Copernicus (1543) and Tycho Brahe (1588), and the unbounded model of Thomas Digges (1576), vied with the bounded geocentric model of Ptolemy (c. 140 AD). The work of the philosopher Giordano Bruno in 1584 lent further support to the Digges model. Despite the eventual acceptance of the unbounded universe, analysis of over 100 modern introductory astronomy texts reveals that these early unbounded models are mentioned infrequently. The ratio of mentions of Digges' model to Copernicus' model has the surprisingly low value of R = 0.08. The philosophical speculation of Bruno receives mention more than twice as often (R = 0.17). The expectation that these early unbounded models warrant inclusion in astronomy texts is supported both by modern hindsight and by the literature of the time. In Shakespeare's "Hamlet" of c. 1601, Prince Hamlet suffers from two transformations. According to the cosmic allegorical model, one transformation changes the bounded geocentricism of Ptolemy to the bounded heliocentricism of Copernicus, while the other completes the change to Digges' model of the infinite universe of suns. This interpretation and the modern world view suggest that both transformations should receive equal mention and thus that the ratio R in introductory texts should be close to unity. This work was supported in part by the NASA West Virginia Space Grant Consortium.

  19. Evaluation of LANDSAT-1 image applications to geologic mapping, structural analysis and mineral resource inventory of South America with special emphasis on the Andes Mountain region

    NASA Technical Reports Server (NTRS)

    Carter, W. D. (Principal Investigator)

    1976-01-01

    The author has identified the following significant results. The discovery of copper mineralization along a lineament mapped in Area 7 (La Paz) has lent credence to the use of LANDSAT 1 data as a basic step in mineral exploration. In Area 9 (Copiapo Region), a number of lineaments were found to be associated with the largest copper deposits of the region. In Area 12 (Magallanes), the identification of what is believed to be a tertiary basin from LANDSAT 1 data has resulted in a new area for petroleum exploration. Band 7 images, as black and white transparencies, were found to be the most useful for geologic interpretation in both tropical vegetated areas and desert regions. Color composites made by the diazochrome process, chromaline process, and from color additive viewers provided additional information. Mosaics of LANDSAT 1 data covering 4 x 6 degrees of latitude and longitude compiled at the 1:1,000,000 scale were found to be an ideal size and format for most users.

  20. Correlates of lending needles/syringes among HIV-seropositive injection drug users.

    PubMed

    Metsch, Lisa R; Pereyra, Margaret; Purcell, David W; Latkin, Carl A; Malow, Robert; Gómez, Cynthia A; Latka, Mary H

    2007-11-01

    Among HIV-positive injection drug users (IDUs), we examined the correlates of lending needles/syringes with HIV-negative and unknown status injection partners. HIV-positive IDUs (N=738) from 4 cities in the United States who reported injection drug use with other IDUs in the past 3 months participated in an audio computer-assisted self-administered interview. Eighteen percent of study participants self-reported having lent their needles to HIV-negative or unknown status injection partners. Multivariate analyses showed that 6 variables were significantly associated with this high-risk injecting practice. Older IDUs, high school graduates, and those reporting more supportive peer norms for safer drug use were less likely to lend needles/syringes. Admission to a hospital for drug treatment in the past 6 months, having injected with >1 person in the past 3 months, and having more psychiatric symptoms were all associated with more risk. These findings underscore the need for a continued prevention focus on HIV-positive IDUs that recognizes the combination of drug use, mental health factors, and social factors that might affect this high-risk injecting practice, which could be associated with HIV and hepatitis C transmission.

  1. Interaction between heat acclimation and exogenous insulin in brown adipose tissue of rats

    NASA Astrophysics Data System (ADS)

    Ohno, H.; Yamashita, H.; Sato, N.; Habara, Y.; Gasa, S.; Nagasawa, J.; Sato, Y.; Ishikawa, M.; Segawa, M.; Yamamoto, M.

    1992-09-01

    Seventy-one male Wistar strain rats (7 weeks old) were kept at 5, 25, or 34° C, respectively, for 2 weeks with or without insulin administration. Insulin (Novo Lente MC) was given subcutaneously in a dose of 3.62 nmol/125 µl saline per 100 g body weight. An apparent effect of insulin treatment was noted only in heat-exposed rats, resulting in a remarkable gain in inter-scapular brown adipose tissue (BAT) mass of heat-acclimated, insulin-treated rats in terms of weight or weight per unit body weight. The BAT from heat-acclimated, insulin-treated rats had significantly higher levels of protein, DNA, RNA, and triglyceride than BAT from heat-acclimated, saline-treated rats. Therefore, it seems likely that the growth of BAT in heat-acclimated, insulin-treated rats was mostly due to the anabolic effects of insulin. The uncoupling protein mRNA was, however, present in BAT of heat-acclimated, insulin-treated rats at rather a depressed level, explaining a corresponding decrease in cold tolerance. On the other hand, the expression of insulin receptor mRNA was attenuated in BAT of rats from all the insulin-treated groups, possibly due to the down-regulation of insulin. Thus, there appeared to be some linkage among BAT, heat acclimation, and insulin.

  2. The short form of the VIA Inventory of Strengths.

    PubMed

    Azañedo, Carolina M; Fernández-Abascal, Enrique G; Barraca, Jorge

    2017-05-01

    The VIA Institute on Character is offering the VIA-120 as the standard VIA Survey, replacing the original 240-item version. The present work involved the construction and the initial evaluation of the Spanish VIA-120 as a short version of the Spanish adaptation of the VIA-IS. This short form was developed using data from 2,143 Spanish-speaking adults. The Spanish VIA-120 was developed by selecting the five items with the highest corrected item-total correlations from the 10 items per subscale of the Spanish VIA-IS. Results lent support to the reliability and validity of this short form to measure the 24 character strengths included in The Values in Action (VIA) classification. The internal consistency coefficients of the subscales of the Spanish version of the VIA-120 were substantially equivalent to the long version. The VIA-120 showed high convergence with the Spanish VIA-IS in terms of descriptive statistics and associations with life satisfaction, positive affect, and negative affect. Factor structure congruence coefficients also indicated very high convergence between the VIA-IS and the short form. The Spanish VIA-120 proved to be a reliable, valid instrument for the assessment of character strengths.

  3. Psychological considerations of man in space: Problems & solutions

    NASA Astrophysics Data System (ADS)

    Kass, J.; Kass, R.; Samaltedinov, I.

    With concrete plans for long duration flight taking form a new impetus is lent to preparing man for this hostile and unnatural environment. Cramped conditions, isolation from family and loved ones, work stress, fear, and incompatibility with fellow crew, are but a few of the problems suffered by astronauts and cosmonauts during their long missions in orbit about the earth. Although criteria for selection of crew is one aspect of attacking the problem, it has not solved it Notwithstanding good selection, team combination, and counselling before flight, problems have still occurred with unwanted consequences. Incompatibility of team members, far from being the exception, has been frequent. This has been detrímental both physiologically and psychologically for the individual as well as for the operational success and safety of the missions. Because problems will inevitably occur in future long duration missions, especially when they are of international and multi-cultural nature, the importance of dealing with them is underlined. This paper takes a different approach towards ameliorating these problems, namely that of psychological group training before a mission.

  4. A study of the fracture process and factors that control toughness variability in Charpy V-notch specimens

    NASA Astrophysics Data System (ADS)

    Bouchard, Real

    La presente etude a ete initiee pour developper une comprehension quantitative du processus de rupture avec les facteurs qui controlent la dispersion des mesures de tenacite lorsque des eprouvettes Charpy entaillees en V sont utilisees. Un grand nombre d'essais ont ete realises pour un acier C-Mn: eprouvettes Charpy testees sous impact, eprouvettes Charpy testees en flexion lente, eprouvettes axisymetriques entaillees et sollicitees en traction et essais de tenacite sur eprouvettes prefissurees. Base sur le concept de la statistique de Weibull, l'approche locale developpee par le groupe Beremin a ete utilisee pour decrire la probabilite de rupture par clivage en fonction de la contrainte appliquee aussi bien qu'en fonction de l'energie Charpy obtenue. Le calcul par elements finis a ete realise pour determiner la distribution de la deformation et des contraintes en pointe d'entaille et de fissure. La nouvelle approche introduite decrit bien les resultats experimentaux. Les points d'initiation du clivage ont ete identifies au MEB et par la suite, avec la technique de faisceau d'ions focalise, sectionnes, polis et examines. L'examen de la microstructure sous le point d'initiation revele clairement que le clivage s'initie par un mecanisme d'empilement de dislocations ou les dislocations sont arretees aux joints de grain, aux interfaces de perlite/ferrite ou de perlite qui agissent comme barrieres physiques.

  5. Complications inattendues de la chirurgie: deux cas de brûlure par plaque de bistouri électrique

    PubMed Central

    Diop, B.; Sy, A.; Ba, P.A.; MBaye, B.; Wane, Y.; Sarre, S.M.

    2016-01-01

    Summary Les risques d’accidents électriques sont une réalité dans les blocs opératoires avec le nombre croissant d’équipements électriques, électroniques et de liquides inflammables utilisés. Le bistouri électrique demeure le dispositif le plus utilisé pour son effet électrochirurgical de coagulation ou section tissulaire. Lorsque qu’elle est défectueuse ou mal placée sur une surface réduite de la peau, la plaque du bistouri peut être à l’origine de brûlure cutanée classiquement profonde, de cicatrisation lente. Elle ajoute à l’affection initiale une surmorbidité iatrogène, inattendue, aux conséquences dévastatrices pour le patient, le chirurgien et parfois la structure hospitalière. Nous rapportons deux cas de brûlure cutanée par plaque de bistouri survenue en peropératoire lors de l’utilisation du bistouri électrique en mode monopolaire et discutons les aspects étiologiques, cliniques et préventifs. PMID:28289364

  6. [Haute Autorite de sante opinion on cost-effectiveness of health products : results and perspectives].

    PubMed

    Midy, Fabienne; Raimond, Véronique; Thébaut, Clémence; Sambuc, Cléa; Rumeau-Pichon, Catherine

    2015-01-01

    Since 3rd October 2013 in France, drug companies applying for reimbursement of an innovative and expensive drug or medical device are required to provide the French National Authority for Health (HAS) with a cost-effectiveness assessment of their product. After a methodological audit of the economic evaluation submitted by the drug company, the Health Economics and Public Health Committee (CEESP) issues an opinion on the expected or observed cost-effectiveness. This opinion is sent to the Pricing Committee (CEPS) which determines the price of the product. After summarizing the French reimburse'!lent and pricing system, the objective of this article is to review the first 22 months of activity, in which HAS issued 30 cost-effectiveness opinions. The process, based on exchanges between drug companies and HAS, allowed the pricing committee to document the economic criterion in the majority of applications, while characterizing the degree of uncertainty of the results. For ten applications, major methodological concerns led the CEESP to reject the drug company's assessment.

  7. Violin

    NASA Astrophysics Data System (ADS)

    Curtin, Joseph; Rossing, Thomas D.

    The first known violins were built in Italy in the early 1500s. While not much is yet known about the instrument's prior development, European forebears include the rebec and the Renaissance fiddle, which themselves evolved from instruments found in the ancient Eastern world. The violin brought together in a particularly happy way features seen in a variety of earlier stringed instruments. Arched plates increased the stiffness-to-mass ratio of the body, creating a more brilliant sound and helping resist long-term deformation. A pronounced waist gave the bow access to the outermost strings, while the precisely calibrated curves of fingerboard and bridge enabled the strings to be played individually as well as in two-, three-, and even four-part chords. In contrast to the viola da gamba and guitar, the violin's top and back plates overhung the ribs, allowing easy removal for repairs, thus contributing to the instrument's fabled longevity. A graceful outline, harmonious proportions, and the minimal use of ornamentation together lent the violin a timeless beauty - explaining in part why it has resisted significant stylistic modification to this day. For a discussion of historical string instruments, see Chap. 17.

  8. The stretch reflex and the contributions of C David Marsden.

    PubMed

    Bhattacharyya, Kalyan B

    2017-01-01

    The stretch reflex or myotatic reflex refers to the contraction of a muscle in response to its passive stretching by increasing its contractility as long as the stretch is within physiological limits. For ages, it was thought that the stretch reflex was of short latency and it was synonymous with the tendon reflex, subserving the same spinal reflex arc. However, disparities in the status of the two reflexes in certain clinical situations led Marsden and his collaborators to carry out a series of experiments that helped to establish that the two reflexes had different pathways. That the two reflexes are dissociated has been proved by the fact that the stretch reflex and the tendon reflex, elicited by stimulation of the same muscle, have different latencies, that of the stretch reflex being considerably longer. They hypothesized that the stretch reflex had a transcortical course before it reached the spinal motor neurons for final firing. Additionally, the phenomenon of stimulus-sensitive cortical myoclonus lent further evidence to the presence of the transcortical loop where the EEG correlate preceded the EMG discharge. This concept has been worked out by later neurologists in great detail, and the general consensus is that indeed, the stretch reflex is endowed with a conspicuous transcortical component.

  9. Parametric display of myocardial function.

    PubMed

    Eusemann, C D; Ritman, E L; Bellemann, M E; Robb, R A

    2001-01-01

    Quantitative assessment of regional heart motion has significant potential to provide more specific diagnosis of cardiac disease and cardiac malfunction than currently possible. Local heart motion may be captured from various medical imaging scanners. In this study, 3-D reconstructions of pre-infarct and post-infarct hearts were obtained from the Dynamic Spatial Reconstructor (DSR)[Ritman EL, Robb RA, Harris LD. Imaging physiological functions: experience with DSR. Philadelphia: Praeger, 1985; Robb RA, Lent AH, Gilbert BK, Chu A. The dynamic spatial reconstructor: a computed tomography system for high-speed simultaneous scanning of multiple cross sections of the heart. J Med Syst 1980;4(2):253-88; Jorgensen SM, Whitlock SV, Thomas PJ, Roessler RW, Ritman EL. The dynamic spatial reconstructor: a high speed, stop action, 3-D, digital radiographic imager of moving internal organs and blood. Proceedings of SPIE, Ultrahigh- and High-speed Photography, Videography, Photonics, and Velocimetry 1990;1346:180-91.] (DSR). Using functional parametric mapping of disturbances in regional contractility and relaxation, regional myocardial motion during a cardiac cycle is color mapped onto a deformable heart model to facilitate appreciation of the structure-to-function relationships in the myocardium, such as occurs in regional patterns of akinesis or dyskinesis associated with myocardial ischemia or infarction resulting from coronary artery occlusion.

  10. Re-surgery and chest wall re-irradiation for recurrent breast cancer - a second curative approach

    PubMed Central

    2011-01-01

    Background Repeat radiation is a rarely used treatment strategy that must be performed with caution. The efficacy and toxicity of a second curative radiotherapy series was investigated in cases of recurrent breast cancer. Methods Forty-two patients treated from 1993 to 2003 with resection (n = 30) and postoperative re-irradiation or definitive re-irradiation (n = 12) for recurrent breast cancer were enrolled in the study. Concurrent hyperthermia was performed in 29 patients. The median age was 57 years. The median pre-radiation exposure was 54Gy. Re-irradiation was conventionally fractionated to a median total dose of 60Gy. Results After a median follow-up of 41 months (range 3-92 months) higher graded late toxicity > G3 according to CTC 3.0 and LENT-SOMA was not observed. The estimated 5-year local control rate reached 62%. The estimated 5-year overall survival rate was 59%. Significantly inferior survival was associated with recurrence within two years (40 vs. 71%, p < ([0-9]).01) and presence of macroscopic tumour load (24 vs. 75%, p = 0.03). Conclusions Repeat radiotherapy for recurrent breast cancer with total radiation doses of 60 Gy and the addition of hyperthermia in the majority of patients was feasible, with acceptable late morbidity and improved prognosis, particularly in patients with previous resection of recurrent tumours. PMID:21609498

  11. Re-surgery and chest wall re-irradiation for recurrent breast cancer: a second curative approach.

    PubMed

    Müller, Arndt-Christian; Eckert, Franziska; Heinrich, Vanessa; Bamberg, Michael; Brucker, Sara; Hehr, Thomas

    2011-05-25

    Repeat radiation is a rarely used treatment strategy that must be performed with caution. The efficacy and toxicity of a second curative radiotherapy series was investigated in cases of recurrent breast cancer. Forty-two patients treated from 1993 to 2003 with resection (n = 30) and postoperative re-irradiation or definitive re-irradiation (n = 12) for recurrent breast cancer were enrolled in the study. Concurrent hyperthermia was performed in 29 patients. The median age was 57 years. The median pre-radiation exposure was 54Gy. Re-irradiation was conventionally fractionated to a median total dose of 60Gy. After a median follow-up of 41 months (range 3-92 months) higher graded late toxicity > G3 according to CTC 3.0 and LENT-SOMA was not observed. The estimated 5-year local control rate reached 62%. The estimated 5-year overall survival rate was 59%. Significantly inferior survival was associated with recurrence within two years (40 vs. 71%, p < ([0-9]).01) and presence of macroscopic tumour load (24 vs. 75%, p = 0.03). Repeat radiotherapy for recurrent breast cancer with total radiation doses of 60 Gy and the addition of hyperthermia in the majority of patients was feasible, with acceptable late morbidity and improved prognosis, particularly in patients with previous resection of recurrent tumours.

  12. The Effect of Dressing Styles and Attitudes of Psychiatrists on Treatment Preferences: Comparison between Patients and Psychiatrists

    PubMed Central

    ATASOY, Nuray; ŞENORMANCI, Ömer; SARAÇLI, Özge; DOĞAN, Veysel; KAYGISIZ, İsmet; ATİK, Levent; ÖRSEL, Sibel

    2015-01-01

    Introduction Recently, different dressing styles and attitudes of psychiatrists have been proposed to enhance the interaction between patients and the physician. The aim of the present study was to investigate the preferences of dressing style and attitudes of a psychiatrist of the patients referred to an outpatient psychiatry clinic and the perception of psychiatrists regarding the preferences of the patients. Methods One hundred and fifty-three patients referred to the outpatient psychiatry clinic of the Bülent Ecevit University School of Medicine, and 94 psychiatrists have been included in the present study. Results When the images of psychiatrists were evaluated in terms of referral for treatment, trust in treatment, and willingness to share their confidential matters, both groups gave minimum scores to causal/sports dress style. While psychiatrists preferred to dress in a suit, casuals, and white coat, the preference order was white coat, casual dress, and suit in the patient group. There was a significant difference between the groups with respect to three dressing styles. Conclusion It can be suggested that psychiatrists assume that patients are traditional in terms of their preference of the dressing style of a doctor and doctor–patient relationship, and a white coat is important to enhance the treatment adherence of patients.

  13. Couches minces de phosphates de titane par voie sol-gel

    NASA Astrophysics Data System (ADS)

    Schmutz, C.; Basset, E.; Barboux, P.

    1993-04-01

    Colloidal solutions of ferroelectrics (KTiOPO4) or ionic conductors (LiTi2(PO4)3) materials have been synthetized. These solutions have been used for thin film synthesis. They are obtained by polycondensation reactions between phosphoric acid esters PO(OH){3-x}(OR)x (with 0 < x < 3 and R = Et, ^nBu, ...) and titanium alkoxides. The ratio POH/Ti and the amount of hydrolysis and the parameters which control the condensation. Nous avons synthétisé des solutions colloïdales de précurseurs de phosphates tels que des ferroélectriques (KTiOPO4) ou des conducteurs ioniques (LiTi2(PO4)3) adaptées au dépôt en couches minces. Elles sont obtenues par des réactions de polycondensation contrôlées entre les esters de l'acide phosphorique PO(OH){3-x}(OR)x (avec 0lent la condensation.

  14. Influence of social cognitive and ethnic variables on academic goals of underrepresented students in science and engineering: a multiple-groups analysis.

    PubMed

    Byars-Winston, Angela; Estrada, Yannine; Howard, Christina; Davis, Dalelia; Zalapa, Juan

    2010-04-01

    This study investigated the academic interests and goals of 223 African American, Latino/a, Southeast Asian, and Native American undergraduate students in two groups: biological science and engineering (S/E) majors. Using social cognitive career theory (Lent, Brown, & Hackett, 1994), we examined the relationships of social cognitive variables (math/science academic self-efficacy, math/science outcome expectations), along with the influence of ethnic variables (ethnic identity, other-group orientation) and perceptions of campus climate to their math/science interests and goal commitment to earn an S/E degree. Path analysis revealed that the hypothesized model provided good overall fit to the data, revealing significant relationships from outcome expectations to interests and to goals. Paths from academic self-efficacy to S/E goals and from interests to S/E goals varied for students in engineering and biological science. For both groups, other-group orientation was positively related to self-efficacy and support was found for an efficacy-mediated relationship between perceived campus climate and goals. Theoretical and practical implications of the study's findings are considered as well as future research directions.

  15. Studies of cancer and radiation dose among atomic bomb survivors. The example of breast cancer.

    PubMed

    Land, C E

    1995-08-02

    A comprehensive program of medical follow-up of survivors of the atomic bombings of Hiroshima and Nagasaki, Japan, by the Radiation Effects Research Foundation (RERF) has produced quantitative estimates of cancer risk from exposure to ionizing radiation. For breast cancer in women, in particular, the strength of the radiation dose response and the generally low level of population risk in the absence of radiation exposure have led to a clear description of excess risk and its variation by age at exposure and over time following exposure. Comparisons of RERF data with data from medically irradiated populations have yielded additional information on the influence of population and underlying breast cancer rates on radiation-related risk. Epidemiological investigations of breast cancer cases and matched controls among atomic bomb survivors have clarified the role of reproductive history as a modifier of the carcinogenic effects of radiation exposure. Finally, a pattern of radiation-related risk by attained age among the survivors exposed during childhood or adolescence suggests the possible existence of a radiation-susceptible subgroup. The hypothetical existence of such a group is lent plausibility by the results of recent family studies suggesting that heritable mutations in certain genes are associated with familial aggregations of breast cancer. The recent isolation and cloning of one such gene, BRCA1, makes it likely that the hypothesis can be tested using molecular assays of archival and other tissue obtained from atomic bomb survivor cases and controls.

  16. Are Members of the Triatoma brasiliensis (Hemiptera, Reduviidae) Species Complex Able to Alter the Biology and Virulence of a Trypanosoma cruzi Strain?

    PubMed

    Costa, J; Araújo, C A C; Freitas, C A V; Borges-Pereira, J

    2015-04-01

    Trypanosoma cruzi is the causative agent of Chagas disease, transmitted to humans and mammals by blood-sucking hemipteran insects belonging to the Triatominae subfamily. The two main genotypes of T. cruzi (TcI and TcII) differ in many characteristics concerning their genetic profile. Despite the extensive literature on vectors and the etiologic agent, several interactive aspects between these two elements of Chagas disease are still waiting to be further clarified. Here, biological and histological features resulting from the interaction between Albino Swiss mice and T. cruzi isolate PB913 after passages through vectors of the Triatoma brasiliensis species complex were evaluated. Comparing the four members of the T. brasiliensis species complex-Triatoma brasiliensis brasiliensis Neiva, Triatoma brasiliensis macromelasoma Galvão, Triatoma melanica Neiva & Lent, and Triatoma juazeirensis Costa & Felix-no significant differences in parasitemia of the infected mice were observed. At 20 days post-infection, the highest number of parasites was observed in the group of mice that were infected with parasites obtained from T. b. macromelasoma. Tropism of the parasites to different organs such as heart, bladder, and skeletal muscles followed by inflammatory cell infiltrates was observed with quantitative and qualitative differences. Even though the four members of the T. brasiliensis species complex differ in their geographical distribution, morphology, biology, ecology, and genetics, no significant influence on the parasitemia of the T. cruzi PB913 isolate was detected. After evaluation of the tissue samples, a higher pathogenicity of parasites obtained from T. b. brasiliensis was noticeable.

  17. Heterozygosity increases microsatellite mutation rate

    PubMed Central

    Amos, William

    2016-01-01

    Whole genome sequencing of families of Arabidopsis has recently lent strong support to the heterozygote instability (HI) hypothesis that heterozygosity locally increases mutation rate. However, there is an important theoretical difference between the impact on base substitutions, where mutation rate increases in regions surrounding a heterozygous site, and the impact of HI on sequences such as microsatellites, where mutations are likely to occur at the heterozygous site itself. At microsatellite loci, HI should create a positive feedback loop, with heterozygosity and mutation rate mutually increasing each other. Direct support for HI acting on microsatellites is limited and contradictory. I therefore analysed AC microsatellites in 1163 genome sequences from the 1000 genomes project. I used the presence of rare alleles, which are likely to be very recent in origin, as a surrogate measure of mutation rate. I show that rare alleles are more likely to occur at locus-population combinations with higher heterozygosity even when all populations carry exactly the same number of alleles. PMID:26740567

  18. Indicators of science, technology, engineering, and math (STEM) career interest among middle school students in the USA

    NASA Astrophysics Data System (ADS)

    Mills, Leila A.

    This study examines middle school students' perceptions of a future career in a science, math, engineering, or technology (STEM) career field. Gender, grade, predispositions to STEM contents, and learner dispositions are examined for changing perceptions and development in career-related choice behavior. Student perceptions as measured by validated measurement instruments are analyzed pre and post participation in a STEM intervention energy-monitoring program that was offered in several U.S. middle schools during the 2009-2010, 2010-2011 school years. A multiple linear regression (MLR) model, developed by incorporating predictors identified by an examination of the literature and a hypothesis-generating pilot study for prediction of STEM career interest, is introduced. Theories on the career choice development process from authors such as Ginzberg, Eccles, and Lent are examined as the basis for recognition of career concept development among students. Multiple linear regression statistics, correlation analysis, and analyses of means are used to examine student data from two separate program years. Study research questions focus on predictive ability, RSQ, of MLR models by gender/grade, and significance of model predictors in order to determine the most significant predictors of STEM career interest, and changes in students' perceptions pre and post program participation. Analysis revealed increases in the perceptions of a science career, decreases in perceptions of a STEM career, increase of the significance of science and mathematics to predictive models, and significant increases in students' perceptions of creative tendencies.

  19. Alkaline phosphatase activity in salivary gland cells of Rhodnius neglectus and R. prolixus (Hemiptera, Triatominae).

    PubMed

    Lima-Oliveira, A P M; Alevi, K C C; Anhê, A C B; Azeredo-Oliveira, M T V

    2016-07-29

    Alkaline phosphatase activity was detected in salivary gland cells of the Rhodnius neglectus Lent, 1954, and R. prolixus Stal, 1859, vectors of Trypanosoma cruzi Chagas, 1909 (etiological agent of Chagas disease) and T. rangeli Tejera, 1920 (pathogenic to insect). The Gomori technique was used to demonstrate alkaline phosphatase activity. Alkaline phosphatase activity was observed throughout the entire gland, with an increased activity in the posterior region of the principal gland. In particular, phosphatase activity was found in the nucleolar corpuscles, suggesting a relationship with the rRNA transcription and ribosomal biogenesis. Alkaline phosphatase was also detected in the nuclear membrane and nuclear matrix, suggesting an association with the nucleo-cytoplasmic transport of ribonucleoproteins and the mechanisms of cell cycle and DNA replication, respectively. This study highlights the importance of alkaline phosphatase in the salivary gland of R. prolixus and R. neglectus and emphasizes its importance in secretory activity. Secretory activity is directly involved in hematophagy and, consequently, in development during metamorphosis. The observed presence of alkaline phosphatase suggests its involvement in the production of saliva allowing feeding of these insects that are important vectors of Chagas disease.

  20. Reinforcement and generalization of productive plural allomorphs in two retarded children1

    PubMed Central

    Sailor, Wayne

    1971-01-01

    Morphological dictates of English usage call for the unvoiced allomorph /-s/ to form the plural of singular nouns with unvoiced endings (e.g., cups). Conversely, the voiced allomorph /-z/ is required to form the plural of nouns with voiced endings (e.g., tree). The study sought to determine the extent to which differential reinforcement could control the acquisition of plural allomorphs in two retarded subjects. In Condition 1, one subject was trained with reinforcement procedures on a list of words calling for the /-s/ allomorph. She was then given unreinforced probe items to determine the extent of generalization to words calling for the /-z/ allomorph. In Condition 2, the procedures were reversed and this subject was trained on a /-z/ list and probed for generalization of /-z/ to words calling for /-s/. A second subject was exposed to the same conditions in the opposite order. The results for the two subjects lent unequivocal support for the hypothesis of generalized training effects. It was concluded that appropriate usage of the linguistic response class “plurals” is susceptible to generalized training effects of differential reinforcement. PMID:16795307

  1. Rupture utérine spontanée sur léiomyosarcome utérin

    PubMed Central

    Boussouni, Khouloud; Benoulaid, Meryem; Dafiri, Rachida

    2016-01-01

    Les sarcomes utérins sont des cancers rares caractérisés par leur polymorphisme clinique et histologique. Ce sont des tumeurs malignes de mauvais pronostic. Ils se révèlent, généralement, par des symptômes non spécifiques à type de douleurs pelviennes, métrorragies. Un tableau d'abdomen aigu avec hémopneumopéritoine est une présentation rare. Nous rapportons le cas d'un léiomyosarcome utérin qui s'est manifesté par une péritonite aigue généralisée inaugurale chez une femme de 43 ans. Le diagnostic de perforation utérine sur tumeur maligne a été suspecté par l'imagerie préopératoire en urgence (échographie et TDM) et confirmé histologiquement. PMID:27642425

  2. Eltgol acutelly improves airway clearance and reduces static pulmonary volumes in adult cystic fibrosis patients.

    PubMed

    Guimarães, Fernando Silva; Lopes, Agnaldo José; Moço, Vanessa Joaquim Ribeiro; Cavalcanti de Souza, Felipe; Silveira de Menezes, Sara Lúcia

    2014-06-01

    Chest physical therapy techniques are essential in order to reduce the frequency of recurrent pulmonary infections that progressively affect lung function in cystic fibrosis patients. Recently, ELTGOL (L'Expiration Lente Totale Glotte Ouverte en décubitus Latéral) emerged as an inexpensive and easy to perform therapeutic option. The aim of this study was to compare the acute effects of ELTGOL and the Flutter valve in stable adult patients with cystic fibrosis. [Subjects and Methods] This was a randomized, crossover study with a sample of cystic fibrosis outpatients. The subjects underwent two protocols (Flutter Valve and ELTGOL interventions, referred to as ELTGOL and FLUTTER) in a randomized order with a one-week washout interval between them. The main outcomes were pulmonary function variables and expectorated sputum dry weight. [Results] ELTGOL cleared 0.34 g more of secretions than FLUTTER (95% CI 0.11 to 0.57). When comparing the physiological effects of ELTGOL and FLUTTER, the first was superior in improving airway resistance (-0.51 cmH2O/L/s; 95% CI -0.88 to -0.14) and airway conductance (0.016 L/s/cmH2O; 95% CI 0.008 to 0.023). [Conclusion] ELTGOL promoted higher secretion removal and improvement in airway resistance and conductance than the Flutter valve. These techniques were equivalent in reducing the pulmonary hyperinflation and air trapping in cystic fibrosis patients.

  3. Chest physiotherapy for collecting sputum samples from HIV-positive patients suspected of having tuberculosis.

    PubMed

    Souza Pinto, V; Bammann, R H

    2007-12-01

    A public referral hospital in Sao Paulo, Brazil. To evaluate chest physiotherapy as a means of obtaining sputum samples from human immunodeficiency virus (HIV) positive in-patients suspected of having pulmonary tuberculosis (TB). A prospective study. Five consecutive samples were collected from 132 patients using the 'spontaneous' technique (ST) on day 1, slow expiration with the glottis open in a lateral posture ('expiration lente totale glotte ouverte en infralatéral', ELTGOL) on day 2, ST on day 3, sputum induction with hypertonic saline (SIHS) on day 4 and ST on day 5. Samples were processed for acid-fast bacilli (AFB) smear and seeded onto Löwenstein-Jensen medium. Mycobacteria were recovered from 34 patients (25.8%). Nine (26.5%) of the strains were identified as mycobacteria other than Mycobacterium tuberculosis. AFB smear sensitivity was higher in ELTGOL samples than in ST or SIHS samples (52.9% vs. 32.4% and 29.4%), although the difference among the three was not significant (P = 0.098). In culture, the three ST samples proved significantly more sensitive (P = 0.05). Physiotherapy shows promise as a technique for obtaining sputum from HIV-positive patients, and AFB testing of a single sample presents high sensitivity. However, this does not preclude the routine collection of three samples, as TB cannot be ruled out before the culture results are known.

  4. Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule.

    PubMed

    Bruno, Stefano; Uliassi, Elisa; Zaffagnini, Mirko; Prati, Federica; Bergamini, Christian; Amorati, Riccardo; Paredi, Gianluca; Margiotta, Marilena; Conti, Paola; Costi, Maria Paola; Kaiser, Marcel; Cavalli, Andrea; Fato, Romana; Bolognesi, Maria Laura

    2017-01-12

    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has recently gained attention as an antiprotozoan and anticancer drug target. We have previously identified 2-phenoxy-1,4-naphthoquinone as an inhibitor of both Trypanosoma brucei and human GAPDH. Herein, through multiple chemical, biochemical, and biological studies, and through the design of analogs, we confirmed the formation of a covalent adduct, we clarified the inhibition mechanism, and we demonstrated antitrypanosomal, antiplasmodial, and cytotoxic activities in cell cultures. The overall results lent support to the hypothesis that 2-phenoxy-1,4-naphthoquinone binds the GAPDH catalytic cysteine covalently through a phenolate displacement mechanism. By investigating the reactivity of 2-phenoxy-1,4-naphthoquinone and its analogs with four GAPDH homologs, we showed that the covalent inhibition is not preceded by the formation of a strong non-covalent complex. However, an up to fivefold difference in inactivation rates among homologs hinted at structural or electrostatic differences of their active sites that could be exploited to further design kinetically selective inhibitors. Moreover, we preliminarily showed that 2-phenoxy-1,4-naphthoquinone displays selectivity for GAPDHs over two other cysteine-dependent enzymes, supporting its suitability as a warhead starting fragment for the design of novel inhibitors.

  5. Expectancy and Conditioning in Placebo Analgesia: Separate or Connected Processes?

    PubMed Central

    Kirsch, Irving; Kong, Jian; Sadler, Pamela; Spaeth, Rosa; Cook, Amanda; Kaptchuk, Ted; Gollub, Randy

    2014-01-01

    Expectancy and conditioning are often tested as opposing explanations of placebo analgesia, most commonly by pitting the effects of a conditioning procedure against those of a verbally-induced expectation for pain reduction. However, conditioning procedures can also alter expectations, such that the effect of conditioning on pain might be mediated by expectancy. We assessed the effect of conditioning on expected pain and placebo-induced pain reduction. Participants were told that the treatment (real or sham acupuncture) would affect one side of the arm but not the other. Because a real acupuncture effect would not be specific to a randomly selected side of the arm, any difference in pain between the “treated” and the “untreated” side would be a placebo effect. There were no significant main effects or interactions associated with type of acupuncture (real versus sham). In both groups, conditioning decreased expected pain for “treated” location and also increased the placebo effect (i.e., the difference in pain report between “treated” and “untreated” locations). In addition, mediation analysis lent support to the hypothesis that the effects of conditioning on placebo analgesia may be mediated by expectancy, although the size of this indirect effect requires further study. PMID:25093194

  6. Understanding the gender gap: Social cognitive changes during an introductory stem course.

    PubMed

    Hardin, Erin E; Longhurst, Melanie O

    2016-03-01

    Despite robust support for the basic theoretical model of social cognitive career theory (Lent, Brown, & Hackett, 1994) and predictions that, for example, increases (or declines) in self-efficacy would lead to subsequent increases (or declines) in interest, there has been surprisingly little longitudinal research that has directly examined the extent to which members of different groups (e.g., women and men) actually do experience changes in critical social-cognitive variables over time early in their curricula in the fields of science, technology, engineering, and mathematics (STEM). Knowing the extent to which such changes occur in typical introductory undergraduate courses is important for targeting interventions to increase persistence of underrepresented groups in STEM. We measured social-cognitive-career-theory-relevant variables near the middle and at the end of the 1st semester of a gateway introductory chemistry course and found that women had lower STEM self-efficacy, coping self-efficacy, and STEM interest than did men, even after controlling for actual course performance. Although there were no detrimental changes across the semester for women or men, men experienced a small but significant increase in their perceived support for pursuing a STEM degree, whereas women did not. (c) 2016 APA, all rights reserved).

  7. Radial Internal Material Handling System (RIMS) for Circular Habitat Volumes

    NASA Technical Reports Server (NTRS)

    Howe, A. Scott; Haselschwardt, Sally

    2012-01-01

    A Radial Internal Material Handling System (RIMS) has been developed to service a circular floor area in variable gravity. On planetary surfaces, pressurized human habitable volumes will require a means to carry heavy equipment between various locations within the volume of the habitat, regardless of the partial gravity (Earth, moon, Mars, etc). On the NASA Habitat Demonstration Unit (HDU), a vertical cylindrical volume, it was determined that a variety of heavy items would need to be carried back and forth from deployed locations to the General Maintenance Work Station (GMWS) when in need of repair, and other equipment may need to be carried inside for repairs, such as rover parts and other external equipment. The vertical cylindrical volume of the HDU lent itself to a circular overhead track and hoist system that allows lifting of heavy objects from anywhere in the habitat to any other point in the habitat interior. In addition, the system is able to hand off lifted items to other material handling systems through the side hatches, such as through an airlock. This paper describes the RIMS system which is scalable for application in a variety of circular habitat volumes.

  8. Light and/or atomic beams to detect ultraweak gravitational effects

    NASA Astrophysics Data System (ADS)

    Tartaglia, Angelo; Belfi, Jacopo; Beverini, Nicolò; Di Virgilio, Angela; Ortolan, Antonello; Porzio, Alberto; Ruggiero, Matteo Luca

    2014-06-01

    We shall review the opportunities lent by ring lasers and atomic beams interferometry in order to reveal gravitomagnetic effects on Earth. Both techniques are based on the asymmetric propagation of waves in the gravitational field of a rotating mass; actually the times of flight for co- or counter-rotating closed paths turn out to be different. After discussing properties and limitations of the two approaches we shall describe the proposed GINGER experiment which is being developed for the Gran Sasso National Laboratories in Italy. The experimental apparatus will consist of a three-dimensional array of square rings, 6m × 6m, that is planned to reach a sensitivity in the order of 1prad/√Hertz or better. This sensitivity would be one order of magnitude better than the best existing ring, which is the G-ring in Wettzell, Bavaria, and would allow for the terrestrial detection of the Lense-Thirring effect and possibly of deviations from General Relativity. The possibility of using either the ring laser approach or atomic interferometry in a space mission will also be considered. The technology problems are under experimental study using both the German G-ring and the smaller G-Pisa ring, located at the Gran Sasso.

  9. Primary progressive aphasia: from syndrome to disease.

    PubMed

    Matías-Guiu, J A; García-Ramos, R

    2013-01-01

    Primary progressive aphasia (PPA) is a clinical syndrome characterised by a progressive decline in language and speech of neurodegenerative origin. Major breakthroughs made in recent years have lent us a better understanding of this syndrome, which may be the first manifestation of any of a number of neurodegenerative diseases. We reviewed the main aspects of PPA epidemiology, clinical manifestations, diagnosis, aetiology and treatment. Most cases manifest sporadically and the typical age of onset is between 50 and 70 years. Three clinically distinct variants have been described: nonfluent or agrammatic PPA, semantic PPA and logopenic PPA. Each of these variants tends to be associated with specific histopathological findings, but clinical diagnostic methods are imperfect predictors of underlying pathology. Anatomical and functional neuroimaging can provide useful biomarkers. Several treatments have been proposed, and while no clear benefits have been demonstrated, acetylcholinesterase inhibitors may be useful, especially in the logopenic variant. PPA is an emerging syndrome which may be more prevalent than we might expect. It was previously listed as part of the frontotemporal dementia spectrum, and it is also related to Alzheimer disease. Clinical diagnosis, complemented by a biomarker evaluation, may predict the underlying pathology, which in turn will improve treatment possibilities. Copyright © 2012 Sociedad Española de Neurología. Published by Elsevier Espana. All rights reserved.

  10. Personalized nutrition and obesity

    PubMed Central

    Qi, Lu

    2017-01-01

    The past few decades have witnessed a rapid rise in nutrition-related disorders such as obesity in the United States and over the world. Traditional nutrition research has associated various foods and nutrients with obesity. Recent advances in genomics have led to identification of the genetic variants determining body weight and related dietary factors such as intakes of energy and macronutrients. In addition, compelling evidence has lent support to interactions between genetic variations and dietary factors in relation to obesity and weight change. Moreover, recently emerging data from other ‘omics’ studies such as epigenomics and metabolomics suggest that more complex interplays between the global features of human body and dietary factors may exist at multiple tiers in affecting individuals’ susceptibility to obesity; and a concept of ‘personalized nutrition’ has been proposed to integrate this novel knowledge with traditional nutrition research, with the hope ultimately to endorse person-centric diet intervention to mitigate obesity and related disorders. PMID:24716734

  11. The Cyclic Peptide Ecumicin Targeting ClpC1 Is Active against Mycobacterium tuberculosis In Vivo

    PubMed Central

    Gao, Wei; Kim, Jin-Yong; Anderson, Jeffrey R.; Akopian, Tatos; Hong, Seungpyo; Jin, Ying-Yu; Kandror, Olga; Kim, Jong-Woo; Lee, In-Ae; Lee, Sun-Young; McAlpine, James B.; Mulugeta, Surafel; Sunoqrot, Suhair; Wang, Yuehong; Yang, Seung-Hwan; Yoon, Tae-Mi; Goldberg, Alfred L.; Pauli, Guido F.; Cho, Sanghyun

    2014-01-01

    Drug-resistant tuberculosis (TB) has lent urgency to finding new drug leads with novel modes of action. A high-throughput screening campaign of >65,000 actinomycete extracts for inhibition of Mycobacterium tuberculosis viability identified ecumicin, a macrocyclic tridecapeptide that exerts potent, selective bactericidal activity against M. tuberculosis in vitro, including nonreplicating cells. Ecumicin retains activity against isolated multiple-drug-resistant (MDR) and extensively drug-resistant (XDR) strains of M. tuberculosis. The subcutaneous administration to mice of ecumicin in a micellar formulation at 20 mg/kg body weight resulted in plasma and lung exposures exceeding the MIC. Complete inhibition of M. tuberculosis growth in the lungs of mice was achieved following 12 doses at 20 or 32 mg/kg. Genome mining of lab-generated, spontaneous ecumicin-resistant M. tuberculosis strains identified the ClpC1 ATPase complex as the putative target, and this was confirmed by a drug affinity response test. ClpC1 functions in protein breakdown with the ClpP1P2 protease complex. Ecumicin markedly enhanced the ATPase activity of wild-type (WT) ClpC1 but prevented activation of proteolysis by ClpC1. Less stimulation was observed with ClpC1 from ecumicin-resistant mutants. Thus, ClpC1 is a valid drug target against M. tuberculosis, and ecumicin may serve as a lead compound for anti-TB drug development. PMID:25421483

  12. The autocatalytic step is an integral part of the hydrogenase cycle.

    PubMed

    Bankó, Sarolta; Kucsma, Zsuzsanna; Lente, Gábor; Bagyinka, Csaba

    2013-03-01

    We earlier proved the involvement of an autocatalytic step in the oxidation of H(2) by HynSL hydrogenase from Thiocapsa roseopersicina, and demonstrated that two enzyme forms interact in this step. Using a modified thin-layer reaction chamber which permits quantitative analysis of the concentration of the reaction product (reduced benzyl viologen) in the reaction volume during the oxidation of H(2), we now show that the steady-state concentration of the product displays a strong enzyme concentration dependence. This experimental fact can be explained only if the previously detected autocatalytic step occurs inside the catalytic enzyme-cycle and not in the enzyme activation process. Consequently, both interacting enzyme forms should participate in the catalytic cycle of the enzyme. As far as we are aware, this is the first experimental observation of such a phenomenon resulting in an apparent inhibition of the enzyme. It is additionally concluded that the interaction of the two enzyme forms should result in a conformational change in the enzyme-substrate form. This scheme is very similar to that of prion reactions. Since merely a few molecules are involved at some point of the reaction, this process is entirely stochastic in nature. We have therefore developed a stochastic calculation method, calculations with which lent support to the conclusion drawn from the experiment. Copyright © 2012 Elsevier B.V. All rights reserved.

  13. Chemical genetic screen in fission yeast reveals roles for vacuolar acidification, mitochondrial fission, and cellular GMP levels in lifespan extension.

    PubMed

    Stephan, Jessica; Franke, Jacqueline; Ehrenhofer-Murray, Ann E

    2013-08-01

    The discovery that genetic mutations in several cellular pathways can increase lifespan has lent support to the notion that pharmacological inhibition of aging pathways can be used to extend lifespan and to slow the onset of age-related diseases. However, so far, only few compounds with such activities have been described. Here, we have conducted a chemical genetic screen for compounds that cause the extension of chronological lifespan of Schizosaccharomyces pombe. We have characterized eight natural products with such activities, which has allowed us to uncover so far unknown anti-aging pathways in S. pombe. The ionophores monensin and nigericin extended lifespan by affecting vacuolar acidification, and this effect depended on the presence of the vacuolar ATPase (V-ATPase) subunits Vma1 and Vma3. Furthermore, prostaglandin J₂ displayed anti-aging properties due to the inhibition of mitochondrial fission, and its effect on longevity required the mitochondrial fission protein Dnm1 as well as the G-protein-coupled glucose receptor Git3. Also, two compounds that inhibit guanosine monophosphate (GMP) synthesis, mycophenolic acid (MPA) and acivicin, caused lifespan extension, indicating that an imbalance in guanine nucleotide levels impinges upon longevity. We furthermore have identified diindolylmethane (DIM), tschimganine, and the compound mixture mangosteen as inhibiting aging. Taken together, these results reveal unanticipated anti-aging activities for several phytochemicals and open up opportunities for the development of novel anti-aging therapies. © 2013 John Wiley & Sons Ltd and the Anatomical Society.

  14. Feathered dinosaurs from China and the evolution of major avian characters.

    PubMed

    Xu, Xing

    2006-03-01

    Recent discoveries of feathered dinosaurs from Early Cretaceous deposits in Liaoning, China, have not only lent strongest support for the dinosaurian hypothesis of bird origins, but have also provided much-needed information about the origins of feathers and avian flight. Preliminary analysis of character evolution suggests that the major avian osteological characters were acquired during the early evolution of maniraptoran dinosaurs. The available evidence also suggests that the first feathers with a filamentous morphology probably evolved in basal coelurosaurs and pennaceous feathers (including those with aerodynamic features) were developed in non-avian maniraptorans, indicating that feathers evolved before the origin of birds and their flight. An evolutionary model is proposed here to describe the major stages of feather evolution, a process characterized by a combination of both transformational and innovative modifications. This model is different from some recent developmental models, which suggest that feathers are evolutionary novelties without a homologous relationship to reptilian scales. Although non-avian theropods are traditionally regarded as distinctly cursorial animals, recent discoveries suggest that the closest relatives of birds might be arboreal theropods. Many bird features, such as the furcula and pennaceous feathers, evolved in a terrestrial context, whereas others, such as some pedal modifications, may have evolved in an arboreal context. Consequently, arboreality may have also contributed to the origin of avian flight.

  15. If exposure to aluminium in antiperspirants presents health risks, its content should be reduced.

    PubMed

    Pineau, Alain; Fauconneau, Bernard; Sappino, André-Pascal; Deloncle, Roger; Guillard, Olivier

    2014-04-01

    Since aluminium (Al) pervades our environment, the scientific community has for many years raised concerns regarding its safety in humans. Al is present in numerous cosmetics such as antiperspirants, lipsticks and sunscreens. Al chlorohydrate is the active antiperspirant agent in underarm cosmetics and may constitute for Al a key exposure route to the human body and a potential source of damage. An in vitro study has demonstrated that Al from antiperspirant can be absorbed through viable human stripped skin. The potential toxicity of Al has been clearly shown and recent works convincingly argue that Al could be involved in cancerogenic processes. Nowadays, for example, Al is suspected of being involved in breast cancer. Recent work in cells in culture has lent credence to the hypothesis that this metal could accumulate in the mammary gland and selectively interfere with the biological properties of breast epithelial cells, thereby promoting a cascade of alterations reminiscent of the early phases of malignant transformation. In addition, several studies suggest that the presence of Al in human breast could influence metastatic process. As a consequence, given that the toxicity of Al has been widely recognized and that it is not a physiological component in human tissues, reducing the concentration of this metal in antiperspirants is a matter of urgency.

  16. Third record of Rhodnius amazonicus and comparative study with R. pictipes (Hemiptera, Reduviidae, Triatominae).

    PubMed

    da Rosa, João Aristeu; Souza, Eder Santos; da Costa Teixeira, Adelson; Barbosa, Rosenildo Ribeiro; de Souza, Aecildo José; Belintani, Tiago; Nascimento, Juliana Damieli; Gil-Santana, Hélcio Reinaldo; de Oliveira, Jader

    2017-12-01

    Rhodnius amazonicus Almeida et al. (1973) is a triatomine of rare occurrence. This species was found for the third time in Breves city, Pará state, Brazil. Morphometric and morphological studies were carried out on one male and one female. Lent and Wygodzinsky (1979) considered this species as a synonym of R. pictipes, until its revalidation after 23 years by Bérenger and Pluot-Sigwalt (2002). Considering the synonym mentioned above, a comparative study between these two species was performed in order to report the third encounter of this species, and increase the number of morphological characters that distinguish R. amazonicus from R. pictipes. The dorsal side of the head, the dorsal and ventral portions of the thorax, the dorsal, ventral and posterior sides of the female genitalia, eggs and the median process of the pygophore were examined by scanning electronic microscopy (SEM). The head, thorax, abdomen and egg parameters of these two species were also measured. The identification of characters on the head, stridulatory sulcus, mesosternum, metasternum, scutellum, process of urotergite I, external female genitalia, pygophore and eggs made the distinction between R. amazonicus and R. pictipes possible. This study has shown the new characters recorded and described for the first time for R. amazonicus and R. pictipes by SEM here made it possible to confirm the morphological separation between these two species. The morphometric analysis also confirmed that the above two taxa are different at specific level. Copyright © 2017. Published by Elsevier B.V.

  17. Benzidine-based dyes: effects of industrial practices, regulations, and world trade on the biological stains market.

    PubMed

    Dapson, R W

    2009-06-01

    One of the most sweeping changes in the dye industry since the advent of synthetic dyes grew out of the health risks associated with benzidine. Dyes made from benzidine and its derivatives were used around the world until adverse health effects become incontrovertible. Workers and family members of workers involved in production and use of benzidine-based dyes had a high incidence of bladder cancer. Following publication of several reports documenting this health hazard, dye makers in the USA, Europe, and Japan phased these dyes out of production in the 1970s. Government regulations lent legal support for these voluntary initiatives. Two strategies subsequently evolved to compensate: developed nations brought alternative substances to market while emerging countries increased production of carcinogenic dyes and sold them at discount prices around the world. Nearly all dye manufacturing now has moved away from nations whose costs of production and compliance rendered them unable to compete. The purpose of this brief review is to publicize the health risks associated with dyes made from benzidine and its congeners, and to alert all companies and end users handling these dyes for biomedical applications that composition of the product and lot-to-lot variability may be problematic because of the manufacturing and distribution practices of the countries where they are produced.

  18. The fate of a progressive science: the Harvard Fatigue Laboratory, athletes, the science of work and the politics of reform.

    PubMed

    Scheffler, Robin Wolfe

    2011-06-01

    In the early twentieth century, fatigue research marked a site of conflicting scientific, industrial, and cultural understandings of working bodies. Many fatigue researchers understood fatigue to be a physiological fact and allied themselves with Progressive-era reformers in urging industrial regulation. Reformers clashed with advocates of Taylorism, who held that productivity could be perpetually increased through managerial efficiency. Histories of this conflict typically cease with the end of the First World War. I examine the work of the Harvard Fatigue Laboratory in the 1920s and 1930s to explore the impact that the introduction of biochemical methods had on the relationship between science and reform. The Laboratory developed sophisticated techniques to study the blood of exercising individuals. In particular, it found that exercising individuals could attain a biochemically "steady state," or equilibrium, and extrapolated from this to assert that fatigue was psychological, not physiological, in nature. In contrast to Progressive-era research, the Laboratory reached this conclusion through laboratory examination, not of workers, but of Laboratory staff members and champion marathon runners. I present the Laboratory's institutional history, scientific work, and finally how common cultural understandings of athletes and work lent plausibility to its efforts to make authoritative statements about industrial conditions.

  19. Deaf students and scientists side-by-side: Self-efficacy and modeling in real-world earth science research

    NASA Astrophysics Data System (ADS)

    Jepson, Patricia Jane

    Deaf and hard of hearing students from five high schools were involved in an earth science project on geological faults. Variables of interest were self-efficacy in science and self-efficacy in career decision-making. The influence and characteristics of role models for deaf and hard of hearing students were also examined. Social cognitive career theory (Lent, Brown, & Hackett, 1994) was used as the theoretical base in this mixed method study. The fault curriculum unit was a collaborative project between Geosciences faculty at the University of Massachusetts and SOAR-High, an earth science program coordinated by the Clerc Center at Gallaudet University. Students participated in three interconnected learning components: (a) classroom experiments using a specially designed sandbox unit to model changes that take place in the earth's crust; (b) videoconferences with geoscientists; and (c) a five-day field trip where students, teachers, and scientists worked side-by-side in the field studying faults in Utah. Quantitative and qualitative data focused on science self-efficacy, career decision-making self-efficacy, and the influence of role models. Results suggested that active, student-centered learning activities had a positive impact on science self-efficacy and career decision making self-efficacy.

  20. Exploring the work lives of adults with serious mental illness from a vocational psychology perspective.

    PubMed

    Millner, Uma Chandrika; Rogers, Erna Sally; Bloch, Philippe; Costa, William; Pritchett, Sharon; Woods, Tracy

    2015-10-01

    Current vocational services for adults with serious mental illness remain largely atheoretical and disconnected from mainstream vocational psychology research and practice. This study explored the perspectives on work of adults with serious mental illness, compared perspectives of young and older adults, and assessed these perspectives for the applicability of a well-established theory of vocational psychology. A national sample of 76 individuals with mental illness engaged in the workforce completed a semistructured questionnaire. We applied the principles of a participatory approach to consensual qualitative research methodology in the study design and data analysis. Results yielded a large number of categories, which clustered under domains representative of the primary constructs of social cognitive career theory (SCCT; Lent, 2013). These domains included the antecedents of self-efficacy, namely, personal accomplishments, vicarious learning, social persuasion, and physical or emotional states as well as additional constructs of outcome expectations, personal goals, and contextual barriers. The SCCT model will likely provide a useful framework to bridge the gap between career development theory and vocational services for individuals with mental illness.

  1. Anévrysme de l’aorte thoracique ascendante post traumatique probable: à propos d’un cas

    PubMed Central

    Amine, Abdellah; Belasri, Salah; Janah, Hicham

    2016-01-01

    Les anévrismes de l'aorte thoracique représentent une affection relativement rare. Les étiologies sont dominées par l'athérosclérose, les dystrophies du tissu élastique et le traumatisme. Les auteurs rapportent le cas d'un patient âgé de 50 ans, ayant comme antécédents pathologiques un traumatisme thoracique sévère à l'âge de 25 ans lors d'un stage de parachutisme, qui consulte pour des signes neurosensoriels d'une hypertension artérielle. La radiographie pulmonaire montre une dilatation anévrismale de l'aorte thoracique. L'échocardiographie trans-thoracique, l'angio-scanner et l'imagerie par résonance magnétique objective un processus anévrismal de l'aorte ascendante. Le bilan d'extension et la recherche étiologique se révèlent négatifs. L'étude anatomo-pathologique de la pièce opératoire montre des lésions non spécifiques. PMID:28292069

  2. A public health physician named Walter Leser.

    PubMed

    Mello, Guilherme Arantes; Bonfim, José Ruben de Alcântara

    2015-09-01

    A brief review of the career of the public health physician Walter Sidney Pereira Leser, who died in 2004 aged 94. Self-taught, from his 1933 doctoral thesis he became a country reference in the field of statistics and epidemiology, with dozens of studies and supervisions. In the clinical field he is one of the founders of Fleury Laboratory, and participates in the creation of CREMESP. As an academic, Leser was a professor at the Escola de Sociologia e Política de São Paulo, Escola Paulista de Medicina e Faculdade de Farmácia e Odontologia da USP. Also, Leser introduced objective tests in the college entrance examination, and led the creation of CESCEM and Carlos Chagas Foundation. In the Escola Paulista de Medicina he created the first Preventive Medicine Department of the country. As a public official, he was secretary of the State Department of Health of São Paulo between 1967 and 1971 and between 1975 and 1979, responsible for extensive reforms and innovations. Among the most remembered, the creation of sanitary medical career. Throughout this legacy, he lent his name to the "Medal of Honor and Merit Public Health Management" of the State of São Paulo.

  3. Binaires semi-détachées : taxonomie

    NASA Astrophysics Data System (ADS)

    Hameury, Jean-Marie

    2001-01-01

    We discuss here compact binaries in which the orbital separation is small enough that mass is transferred from one star to the other. These systems are classified according to the nature of the primary: algols for ordinary stars, cataclysmic variables for white dwarfs, and X-ray binaries for black holes and neutron stars. These classes are often studied separately, even though the same physical processes occur in all objects; a global approach is most useful for understanding these objects and the physical processes. On discutera ici des binaires serrées dans lesquelles la séparation est suffisamment faible pour qu'il y ait échange de matière entre les deux étoiles. La classification de ces systèmes est liée à la nature de l'étoile accrétante: algols pour la séquence principale, variables cataclysmiques pour les naines blanches, et binaires X pour les étoiles à neutrons ou les trous noirs. Ces classes sont souvent étudiées de façon séparée, mais elles révèlent des processus physiques communs; la compréhension des objets et de la physique sous-jacente bénéficie d'une approche globale.

  4. Morphological specializations of baleen whales associated with hydrodynamic performance and ecological niche.

    PubMed

    Woodward, Becky L; Winn, Jeremy P; Fish, Frank E

    2006-11-01

    Feeding behavior, prey type, and habitat appear to be associated with the morphological design of body, fluke, and flippers in baleen whales. Morphometric data from whaling records and recent stranding events were compiled, and morphometric parameters describing the body length, and fluke and flipper dimensions for an "average" blue whale Balaenoptera musculus, humpback whale Megaptera novaeangliae, gray whale Eschrichtius robustus, and right whale Eubalaena glacialis were determined. Body mass, body volume, body surface area, and fluke and flipper surface areas were estimated. The resultant morphological configurations lent themselves to the following classifications based on hydrodynamic principles: fast cruiser, slow cruiser, fast maneuverer, and slow maneuverer. Blue whales have highly streamlined bodies with small, high aspect ratio flippers and flukes for fast efficient cruising in the open ocean. On the other hand, the rotund right whale has large, high aspect ratio flukes for efficient slow speed cruising that is optimal for their continuous filter feeding technique. Humpbacks have large, high aspect ratio flippers and a large, low aspect ratio tail for quick acceleration and high-speed maneuvering which would help them catch their elusive prey, while gray whales have large, low aspect ratio flippers and flukes for enhanced low-speed maneuvering in complex coastal water habitats.

  5. Teaching ethics in the clinic. The theory and practice of moral case deliberation.

    PubMed

    Molewijk, A C; Abma, T; Stolper, M; Widdershoven, G

    2008-02-01

    A traditional approach to teaching medical ethics aims to provide knowledge about ethics. This is in line with an epistemological view on ethics in which moral expertise is assumed to be located in theoretical knowledge and not in the moral experience of healthcare professionals. The aim of this paper is to present an alternative, contextual approach to teaching ethics, which is grounded in a pragmatic-hermeneutical and dialogical ethics. This approach is called moral case deliberation. Within moral case deliberation, healthcare professionals bring in their actual moral questions during a structured dialogue. The ethicist facilitates the learning process by using various conversation methods in order to find answers to the case and to develop moral competencies. The case deliberations are not unique events, but are a structural part of the professional training on the work floor within healthcare institutions. This article presents the underlying theory on (teaching) ethics and illustrates this approach with an example of a moral case deliberation project in a Dutch psychiatric hospital. The project was evaluated using the method of responsive evaluation. This method provided us with rich information about the implementation process and effects the research process itself also lent support to the process of implementation.

  6. The Association of Academic Health Sciences Libraries Annual Statistics: an exploratory twenty-five-year trend analysis.

    PubMed

    Byrd, Gary D; Shedlock, James

    2003-04-01

    This paper presents an exploratory trend analysis of the statistics published over the past twenty-four editions of the Annual Statistics of Medical School Libraries in the United States and Canada. The analysis focuses on the small subset of nineteen consistently collected data variables (out of 656 variables collected during the history of the survey) to provide a general picture of the growth and changing dimensions of services and resources provided by academic health sciences libraries over those two and one-half decades. The paper also analyzes survey response patterns for U.S. and Canadian medical school libraries, as well as osteopathic medical school libraries surveyed since 1987. The trends show steady, but not dramatic, increases in annual means for total volumes collected, expenditures for staff, collections and other operating costs, personnel numbers and salaries, interlibrary lending and borrowing, reference questions, and service hours. However, when controlled for inflation, most categories of expenditure have just managed to stay level. The exceptions have been expenditures for staff development and travel and for collections, which have both outpaced inflation. The fill rate for interlibrary lending requests has remained steady at about 75%, but the mean ratio of items lent to items borrowed has decreased by nearly 50%.

  7. The center-cut solution.

    PubMed

    Firnstahl, T W

    1993-01-01

    Timothy Firnstahl owns five successful restaurants in Seattle, but he recently came very close to owning none. In the early 1990s, he found himself, like so many restauranteurs, facing rising costs, inefficient management, and a recession. Confronting financial annihilation, Firnstahl had to act quickly: since he had no peripherals to trim, he cut off the head of his company. Remarkably, it worked. Firnstahl's problem was his new and innovative restaurant, Sharps Fresh Roasting. The heart of the Sharps concept was a unique long-roasting technique that made lean, inexpensive meats taste as juicy and delicious as fattier, expensive cuts. The process also lent itself to faster service and lower labor costs. But it wasn't working. Sharps wasn't breaking even, and his other restaurants couldn't make up the difference. He needed a solution fast. Firnstahl got his answer from Mikhail Gorbachev: slash the centralized command and liberate the company. In doing so, he would also transfer virtually all power and responsibility to his line managers. And after five months of intensive study and planning, he accomplished what he set out to do. He fired most of his corporate staff, empowered his restaurant managers with "100% Power and Responsibility," and, finally, undertook a massive promotion campaign. A year later, Sharps Fresh Roasting is the gold mine Firnstahl always believed it could be. He's done away with bureaucracy and turned business around in a down market. All this because his managers are managing themselves.

  8. Development of radiation damage during in-situ Kr++ irradiation of Fesbnd Nisbnd Cr model austenitic steels

    NASA Astrophysics Data System (ADS)

    Desormeaux, M.; Rouxel, B.; Motta, A. T.; Kirk, M.; Bisor, C.; de Carlan, Y.; Legris, A.

    2016-07-01

    In situ irradiations of 15Cr/15Nisbnd Ti and 15Cr/25Nisbnd Ti model austenitic steels were performed at the Intermediate Voltage Electron Microscope (IVEM)-Tandem user Facility (Argonne National Laboratory) at 600 °C using 1 MeV Kr++. The experiment was designed in the framework of cladding development for the GEN IV Sodium Fast Reactors (SFR). It is an extension of previous high dose irradiations on those model alloys at JANNuS-Saclay facility in France, aimed at investigating swelling mechanisms and microstructure evolution of these alloys under irradiation [1]. These studies showed a strong influence of Ni in decreasing swelling. In situ irradiations were used to continuously follow the microstructure evolution during irradiation using both diffraction contrast imaging and recording of diffraction patterns. Defect analysis, including defect size, density and nature, was performed to characterize the evolving microstructure and the swelling. Comparison of 15Cr/15Nisbnd Ti and 15Cr/25Nisbnd Ti irradiated microstructure has lent insight into the effect of nickel content in the development of radiation damage caused by heavy ion irradiation. The results are quantified and discussed in this paper.

  9. Cutting the Flesh: Surgery, Autopsy and Cannibalism in the Belgian Congo

    PubMed Central

    Au, Sokhieng

    2017-01-01

    Within the colonial setting of the Belgian Congo, the process of cutting the body, whether living or dead, lent itself to conflation with cannibalism and other fantastic consumption stories by both Congolese and Belgian observers. In part this was due to the instability of the meaning of the human body and the human corpse in the colonial setting. This essay maps out different views of the cadaver and personhood through medical technologies of opening the body in the Belgian Congo. The attempt to impose a specific reading of the human body on the Congolese populations through anatomy and related Western medical disciplines was unsuccessful. Ultimately, practices such as surgery and autopsy were reinterpreted and reshaped in the colonial context, as were the definitions of social and medical death. By examining the conflicts that arose around medical technologies of cutting human flesh, this essay traces multiple parallel narratives on acceptable use and representation of the human body (Congolese or Belgian) beyond its medical assignation. PMID:28260570

  10. Infall of gas as the formation mechanism of stars up to 20 times more massive than the Sun.

    PubMed

    Beltrán, Maria T; Cesaroni, Riccardo; Codella, Claudio; Testi, Leonardo; Furuya, Ray S; Olmi, Luca

    2006-09-28

    Theory predicts and observations confirm that low-mass stars (like the Sun) in their early life grow by accreting gas from the surrounding material. But for stars approximately 10 times more massive than the Sun (approximately 10M(o)), the powerful stellar radiation is expected to inhibit accretion and thus limit the growth of their mass. Clearly, stars with masses >10M(o) exist, so there must be a way for them to form. The problem may be solved by non-spherical accretion, which allows some of the stellar photons to escape along the symmetry axis where the density is lower. The recent detection of rotating disks and toroids around very young massive stars has lent support to the idea that high-mass ( > 8M(o)) stars could form in this way. Here we report observations of an ammonia line towards a high-mass star forming region. We conclude that the gas is falling inwards towards a very young star of approximately 20M(o), in line with theoretical predictions of non-spherical accretion.

  11. Insights into how nucleotide supplements enhance the peroxidase-mimicking DNAzyme activity of the G-quadruplex/hemin system.

    PubMed

    Stefan, Loic; Denat, Franck; Monchaud, David

    2012-09-01

    Since the initial discovery of the catalytic capability of short DNA fragments, this peculiar enzyme-like property (termed DNAzyme) has continued to garner much interest in the scientific community because of the virtually unlimited applications in developing new molecular devices. Alongside the exponential rise in the number of DNAzyme applications in the last past years, the search for convenient ways to improve its overall efficiency has only started to emerge. Credence has been lent to this strategy by the recent demonstration that the quadruplex-based DNAzyme proficiency can be enhanced by ATP supplements. Herein, we have made a further leap along this path, trying first of all to decipher the actual DNAzyme catalytic cycle (to gain insights into the steps ATP may influence), and subsequently investigating in detail the influence of all the parameters that govern the catalytic efficiency. We have extended this study to other nucleotides and quadruplexes, thus demonstrating the versatility and broad applicability of such an approach. The defined exquisitely efficient DNAzyme protocols were exploited to highlight the enticing advantages of this method via a 96-well plate experiment that enables the detection of nanomolar DNA concentrations in real-time with the naked-eye (see movie as Supplementary Data).

  12. A Qualitative Study to Inform the Development of a Videogame for Adolescent Human Immunodeficiency Virus Prevention

    PubMed Central

    Rosenthal, Marjorie S.; Camenga, Deepa R.; Edelman, E. Jennifer; Fiellin, Lynn E.

    2012-01-01

    Abstract We used qualitative methods to inform the development of an interactive videogame focused on behavior change to reduce risk and promote human immunodeficiency virus (HIV) prevention in young minority adolescents. Guided by community-partnered research principles, we conducted and analyzed 16 individual interviews and six focus groups with 10–15 year-old boys and girls (36 unique participants) at a neighborhood-based nonprofit organization serving youth from low-resource neighborhoods. Three recurrent themes lent themselves to translation into a videogame-based intervention. Adolescents reported protective factors and facilitators to engaging in risk behaviors, including (1) their personal ability to balance the tension between individuation and group membership, (2) the presence of stable mentor figures in their life, and (3) the neighborhood in which they live. We used these themes to inform the design of our videogame intervention with the goal that these methods may increase the intervention's efficacy at promoting HIV prevention by making them more tailored and relevant to a specific population. Our qualitative study provides a practical understanding of how important elements identified by minority youth regarding negotiating around risk behaviors can be integrated into a videogame intervention. These findings offer valuable insights to researchers whose goal is to design effective and tailored interventions to affect behavior change. PMID:24078897

  13. Should Hypersexual Disorder be Classified as an Addiction?

    PubMed Central

    Kor, Ariel; Fogel, Yehuda; Reid, Rory C.; Potenza, Marc N.

    2013-01-01

    Hypersexual behavior has been documented within clinical and research settings over the past decade. Despite recent research on hypersexuality and its associated features, many questions remain how best to define and classify hypersexual behavior. Proposed diagnostic criteria for Hypersexual Disorder (HD) have been proposed for the DSM-5 and a preliminary field trial has lent some support to the reliability and validity of the HD diagnosis. However, debate exists with respect to the extent to which the disorder might be categorized as a non-substance or behavioral addiction. In this article, we will discuss this debate in the context of data citing similarities and differences between hypersexual disorder, drug addictions, and pathological gambling. The authors of this paper conclude that despite many similarities between the features of hypersexual behavior and substance-related disorders, the research on HD at this time is in its infancy and much remains to be learned before definitively characterizing HD as an addiction at this time. PMID:24273404

  14. Does the periodic vegetarianism of Greek Orthodox Christians benefit blood pressure?

    PubMed

    Sarri, Katerina; Linardakis, Manolis; Codrington, Caroline; Kafatos, Anthony

    2007-04-01

    The Greek Orthodox Christian (GOC) diet is a periodic vegetarian-type diet that shares all the characteristics of the Mediterranean diet. No study to date has investigated its impact on blood pressure (BP). Thirty-eight devout Orthodox Christian fasters and 29 matched controls living in Crete, Greece, were followed for 1 year during 2001. BP data were gathered before (pre) and near completion (end) of the three major fasting periods of the Orthodox Christian calendar [Christmas (40 days)-Easter (48 days)-Assumption (15 days)] along with other information on their dietary and lifestyle habits, body measurements and blood samples. Throughout the study fasters had higher mean SBP and DBP than controls. No fasting period had a significant BP lowering effect on fasters. Fasters' prevalence of end-Christmas and end-Lent high-normal BP was significantly higher than that of the controls', while it was reduced during the Assumption and reached the very low levels of controls'. On the whole, compared to controls, fasters increased their fiber, magnesium and fruit and vegetable consumption during the fasting periods and decreased their sodium and calcium intake. BMI and blood lipids were significantly associated with SBP/DBP at almost all measurements. Religious adherence to a periodic vegetarian Mediterranean-style diet does not have an observable effect on BP. Further research is needed in order to establish conclusive evidence.

  15. Impact of caloric and dietary restriction regimens on markers of health and longevity in humans and animals: a summary of available findings.

    PubMed

    Trepanowski, John F; Canale, Robert E; Marshall, Kate E; Kabir, Mohammad M; Bloomer, Richard J

    2011-10-07

    Considerable interest has been shown in the ability of caloric restriction (CR) to improve multiple parameters of health and to extend lifespan. CR is the reduction of caloric intake - typically by 20 - 40% of ad libitum consumption - while maintaining adequate nutrient intake. Several alternatives to CR exist. CR combined with exercise (CE) consists of both decreased caloric intake and increased caloric expenditure. Alternate-day fasting (ADF) consists of two interchanging days; one day, subjects may consume food ad libitum (sometimes equaling twice the normal intake); on the other day, food is reduced or withheld altogether. Dietary restriction (DR) - restriction of one or more components of intake (typically macronutrients) with minimal to no reduction in total caloric intake - is another alternative to CR. Many religions incorporate one or more forms of food restriction. The following religious fasting periods are featured in this review: 1) Islamic Ramadan; 2) the three principal fasting periods of Greek Orthodox Christianity (Nativity, Lent, and the Assumption); and 3) the Biblical-based Daniel Fast. This review provides a summary of the current state of knowledge related to CR and DR. A specific section is provided that illustrates related work pertaining to religious forms of food restriction. Where available, studies involving both humans and animals are presented. The review includes suggestions for future research pertaining to the topics of discussion.

  16. Effects of Greek Orthodox Christian Church fasting on serum lipids and obesity.

    PubMed

    Sarri, Katerina O; Tzanakis, Nikolaos E; Linardakis, Manolis K; Mamalakis, George D; Kafatos, Anthony G

    2003-05-16

    No study to date has focused on the impact of Greek Orthodox Christian fasting on serum lipoproteins and obesity yet. 120 Greek adults were followed longitudinally for one year. Sixty fasted regularly in all fasting periods (fasters) and 60 did not fast at all (controls). The three major fasting periods under study were: Christmas (40 days), Lent (48 days) and Assumption (August, 15 days). A total of 6 measurements were made during one year including pre- and end-fasting blood collection, serum lipoprotein analyses and anthropometric measurements. Statistically significant end-fasting total and LDL cholesterol differences were found in fasters. Fasters compared to controls presented 12.5% lower end-total cholesterol (p < 0.001), 15.9% lower end-LDL cholesterol (p < 0.001) and 1.5% lower end-BMI (p < 0.001). The end- LDL/HDL ratio was lower in fasters (6.5%, p < 0.05) while the change in end- HDL cholesterol in fasters (4.6% decline) was not significant. Similar results were found when the pre- and end-fasting values of fasters were compared. No change was found in control subjects. Adherence to Greek Orthodox fasting periods contributes to a reduction in the blood lipid profile including a non-significant reduction in HDL cholesterol and possible impact on obesity.

  17. The monzogabbroic intrusion in the island of Vulcano, Aeolian Archipelago, Italy

    NASA Astrophysics Data System (ADS)

    Faraone, D.; Silvano, A.; Verdiani, G.

    1986-10-01

    Two drill-holes were carried out during 1983 84 by the “Joint Venture” AGIP-EMS-ENEL on the island of Vulcano southwest of the Cratere della Fossa. After passing through pyroclastics and lavas of the young volcanic centres of Vulcano the drill-holes penetrated an intrusion of monzogabbro to leuco-monzogabbro composition. In one of the holes the top of the intrusion occurs at 1360 m and the intrusive rocks are found to the bottom of the well at 2050 m. At this depth the temperature exceeds 419 °C and the temperature gradients are sufficiently steep that magma could well be reached only a few hundred metres deeper. Lava of the South Vulcano centre is metamorphosed by the intrusion. A massive pyroclastic bed, underlying the welded scoriae deposits associated with collapse of the Caldera del Piano system, contains blocks of the intrusion. Radiometric data suggest an intrusion age of 30 000 years. Geophysical data indicate that the main intrusion is a shallow level and is located in the stretch of sea west of Mt. Lentìa.

  18. [Evaluation of emergency services of the hospitals from the QualiSUS program].

    PubMed

    O'Dwyer, Gisele Oliveira; de Oliveira, Sergio Pacheco; de Seta, Marismary Horsth

    2009-01-01

    The aid lent by the emergency services is the object of this paper, which aims to assess the emergency service of the QualiSUS program. The study is descriptive with the application of a questionnaire to the responsible of the emergency services in eight hospitals. The emergency services were always overcrowded, and the causes pointed were the low resolutivity of basic attention and the precariousness of the hospital network. Contributing to this there is the primary care decreased resolutivity and the precariousness of the hospital network. Six hospitals do not manage the emergency service. The entrance system is not organized and only three hospitals work with risk classification. All of them refer difficulties with internal and external services. The hardest pathologies to refer to other services are the chronicles, neurological and social. The professionals do not have specific qualification and the precariousness job contracts do not contribute neither for the professional's fixation nor for his qualification. Clinical protocols are used by one service. It was noticed the influence of the QualiSUS in the hospitals. The failure of the health services network interferes with the emergency patient's profile. The investment of the QualiSUS cannot be restrained to the hospital. Emergency should be more integrated to the system and hospital. The qualification of human resources is indispensable as well as the bed's regulation.

  19. Radial Internal Material Handling System (RIMS) for Circular Habitat Volumes

    NASA Technical Reports Server (NTRS)

    Howe, A. Scott; Haselschwardt, Sally

    2012-01-01

    A Radial Internal Material Handling System (RIMS) has been developed to service a circular floor area in variable gravity. On planetary surfaces, pressurized human habitable volumes will require a means to carry heavy equipment between various locations within the volume of the habitat, regardless of the partial gravity (Earth, moon, Mars, etc). On the NASA Habitat Demonstration Unit (HDU), a vertical cylindrical volume, it was determined that a variety of heavy items would need to be carried back and forth from deployed locations to the General Maintenance Work Station (GMWS) when in need of repair, and other equipment may need to be carried inside for repairs, such as rover parts and other external equipment. The vertical cylindrical volume of the HDU lent itself to a circular overhead track and hoist system that allows lifting of heavy objects from anywhere in the habitat to any other point in the habitat interior. In addition, the system is able to hand off lifted items to other material handling systems through the side hatches, such as through an airlock. This paper describes the RIMS system which is scalable for application in a variety of circular habitat volumes.

  20. Using multiple pharmacoeconomic methods to conduct a cost-effectiveness analysis of histamine H2-receptor antagonists.

    PubMed

    McCoy, S; Blayney-Chandramouli, J; Mutnick, A

    1998-12-15

    A formulary decision at a health care institution was studied by using two pharmacoeconomic methods. A pharmacoeconomic study was undertaken to assess the impact of a 1995 formulary decision to designate cimetidine as the primary histamine H2-receptor antagonist (H2RA) and to restrict the use of famotidine. Consecutive patients receiving either i.v. cimetidine or famotidine for stress ulcer prophylaxis were reviewed during a two-month period in 1997, and information on demographics, dosage and duration of H2RA therapy, admission date, laboratory test values, and adverse drug reactions was collected. Data for 62 patients (43 cimetidine recipients and 19 famotidine recipients) were evaluated. Therapy was categorized as successful or failed, and the data were then evaluated by decision analysis to evaluate the cost-effectiveness of the agents and by multiattribute utility theory (MAUT) to incorporate a humanistic evaluation of the treatments, namely, the number of doses administered and the number of times dosages were changed. The decision tree revealed that the average cost of receiving cimetidine was $82.01 and the average cost of famotidine therapy was $92.45. The MAUT analysis showed that cimetidine was the preferred agent as long as cost was valued at greater than 60% of the decision-making process and efficacy remained equal between the two agents. Two pharmacoeconomic methods lent support to a formulary decision at a health care institution.