Science.gov

Sample records for lepton-hyperon interactions

  1. Interactive numerals

    PubMed Central

    2017-01-01

    Although Arabic numerals (like ‘2016’ and ‘3.14’) are ubiquitous, we show that in interactive computer applications they are often misleading and surprisingly unreliable. We introduce interactive numerals as a new concept and show, like Roman numerals and Arabic numerals, interactive numerals introduce another way of using and thinking about numbers. Properly understanding interactive numerals is essential for all computer applications that involve numerical data entered by users, including finance, medicine, aviation and science. PMID:28484609

  2. Media Interaction.

    ERIC Educational Resources Information Center

    Nordlund, Jan-Erik

    1978-01-01

    Defines and operationalizes the concept of media interaction, which implies that the audience member experiences "interaction" with, and in many cases identifies with, persons in the media content. Presents a model of media interaction and the results of surveys conducted to explore hypotheses derived form the model. (JMF)

  3. Interacting faults

    NASA Astrophysics Data System (ADS)

    Peacock, D. C. P.; Nixon, C. W.; Rotevatn, A.; Sanderson, D. J.; Zuluaga, L. F.

    2017-04-01

    The way that faults interact with each other controls fault geometries, displacements and strains. Faults rarely occur individually but as sets or networks, with the arrangement of these faults producing a variety of different fault interactions. Fault interactions are characterised in terms of the following: 1) Geometry - the spatial arrangement of the faults. Interacting faults may or may not be geometrically linked (i.e. physically connected), when fault planes share an intersection line. 2) Kinematics - the displacement distributions of the interacting faults and whether the displacement directions are parallel, perpendicular or oblique to the intersection line. Interacting faults may or may not be kinematically linked, where the displacements, stresses and strains of one fault influences those of the other. 3) Displacement and strain in the interaction zone - whether the faults have the same or opposite displacement directions, and if extension or contraction dominates in the acute bisector between the faults. 4) Chronology - the relative ages of the faults. This characterisation scheme is used to suggest a classification for interacting faults. Different types of interaction are illustrated using metre-scale faults from the Mesozoic rocks of Somerset and examples from the literature.

  4. Imagined Interactions

    ERIC Educational Resources Information Center

    Honeycutt, James M.

    2010-01-01

    Social scientists have been studying imagined interactions since the mid-1980s and have measured numerous physiological correlates (Honeycutt, 2010). In this commentary I assess the research reported in Crisp and Turner (May-June 2009) and highlight the underlying mechanisms of imagined interactions that have empirically been laid out across…

  5. Imagined Interactions

    ERIC Educational Resources Information Center

    Honeycutt, James M.

    2010-01-01

    Social scientists have been studying imagined interactions since the mid-1980s and have measured numerous physiological correlates (Honeycutt, 2010). In this commentary I assess the research reported in Crisp and Turner (May-June 2009) and highlight the underlying mechanisms of imagined interactions that have empirically been laid out across…

  6. Interacting parasites

    USGS Publications Warehouse

    Lafferty, Kevin D.

    2010-01-01

    Parasitism is the most popular life-style on Earth, and many vertebrates host more than one kind of parasite at a time. A common assumption is that parasite species rarely interact, because they often exploit different tissues in a host, and this use of discrete resources limits competition (1). On page 243 of this issue, however, Telfer et al. (2) provide a convincing case of a highly interactive parasite community in voles, and show how infection with one parasite can affect susceptibility to others. If some human parasites are equally interactive, our current, disease-by-disease approach to modeling and treating infectious diseases is inadequate (3).

  7. Interacting Galaxies

    NASA Image and Video Library

    2008-04-24

    This beautiful pair of interacting galaxies consists of NGC 5754, the large spiral on the right, and NGC 5752, the smaller companion in the bottom left corner of the image. This image is from NASA Hubble Space Telescope.

  8. Interactive training.

    PubMed

    Toogood, Sandy

    2008-09-01

    Active support (AS) was developed to help staff organise and deliver practical support for meaningful client engagement in everyday activities. Both the amount and momentary effectiveness of staff support for client engagement have been found to increase following AS training. Training typically consists of a combination of workshops and onsite coaching sessions. To date, onsite training procedures have not been described or evaluated independently of AS workshops. An onsite training procedure used in AS--interactive training (IT)--was evaluated independently of AS workshops through direct observation of staff and client behaviour. Staff views were canvassed via a questionnaire. Following interactive training, staff assistance and client engagement increased. Staff views on the experience were positive. Results from this preliminary study suggest that further research on the effectiveness of interactive training is warranted.

  9. Weak Interactions

    DOE R&D Accomplishments Database

    Lee, T. D.

    1957-06-01

    Experimental results on the non-conservation of parity and charge conservation in weak interactions are reviewed. The two-component theory of the neutrino is discussed. Lepton reactions are examined under the assumption of the law of conservation of leptons and that the neutrino is described by a two- component theory. From the results of this examination, the universal Fermi interactions are analyzed. Although reactions involving the neutrino can be described, the same is not true of reactions which do not involve the lepton, as the discussion of the decay of K mesons and hyperons shows. The question of the invariance of time reversal is next examined. (J.S.R.)

  10. Interacting Compasses

    NASA Astrophysics Data System (ADS)

    Riveros, Héctor G.; Betancourt, Julián

    2009-10-01

    The use of multiple compasses to map and visualize magnetic fields is well-known. The magnetic field exerts a torque on the compasses aligning them along the lines of force. Some science museums show the field of a magnet using a table with many compasses in a closely packed arrangement. However, the very interesting interactions that occur between the compasses themselves are frequently neglected. In this paper we describe demonstrations, using arrays of compasses, that show these interactions and model magnetic domains in ferromagnetic materials.

  11. Interactive Video.

    ERIC Educational Resources Information Center

    Boyce, Carol

    1992-01-01

    A workshop on interactive video was designed for fourth and fifth grade students, with the goals of familiarizing students with laser disc technology, developing a cadre of trained students to train other students and staff, and challenging able learners to utilize higher level thinking skills while conducting a research project. (JDD)

  12. Interactive Astronomy.

    ERIC Educational Resources Information Center

    Martin, Jean K.

    1997-01-01

    Presents guiding principles for developing interactive lessons for the World Wide Web. Describes "Amazing Space: Education Online from the Hubble Space Telescope", a program where students study spectacular Hubble Space Telescope images of stars and star-forming regions to learn about the life cycle of stars and the creation of atoms. (JRH)

  13. Constructive Interaction.

    ERIC Educational Resources Information Center

    Miyake, Naomi

    To identify conditions that make a conversational interaction constructive--in the sense that the participants can find the way toward the success of what they wanted to accomplish--two situations were examined. In one, a professional researcher explained her data to a statistician. In the other, three groups of two people cooperated with each…

  14. Interacting Compasses

    ERIC Educational Resources Information Center

    Riveros, Hector G.; Betancourt, Julian

    2009-01-01

    The use of multiple compasses to map and visualize magnetic fields is well-known. The magnetic field exerts a torque on the compasses aligning them along the lines of force. Some science museums show the field of a magnet using a table with many compasses in a closely packed arrangement. However, the very interesting interactions that occur…

  15. Interactive Astronomy.

    ERIC Educational Resources Information Center

    Martin, Jean K.

    1997-01-01

    Presents guiding principles for developing interactive lessons for the World Wide Web. Describes "Amazing Space: Education Online from the Hubble Space Telescope", a program where students study spectacular Hubble Space Telescope images of stars and star-forming regions to learn about the life cycle of stars and the creation of atoms. (JRH)

  16. Interacting Compasses

    ERIC Educational Resources Information Center

    Riveros, Hector G.; Betancourt, Julian

    2009-01-01

    The use of multiple compasses to map and visualize magnetic fields is well-known. The magnetic field exerts a torque on the compasses aligning them along the lines of force. Some science museums show the field of a magnet using a table with many compasses in a closely packed arrangement. However, the very interesting interactions that occur…

  17. Interactive Macroeconomics

    NASA Astrophysics Data System (ADS)

    Di Guilmi, Corrado; Gallegati, Mauro; Landini, Simone

    2017-04-01

    Preface; List of tables; List of figures, 1. Introduction; Part I. Methodological Notes and Tools: 2. The state space notion; 3. The master equation; Part II. Applications to HIA Based Models: 4. Financial fragility and macroeconomic dynamics I: heterogeneity and interaction; 5. Financial fragility and macroeconomic Dynamics II: learning; Part III. Conclusions: 6. Conclusive remarks; Part IV. Appendices and Complements: Appendix A: Complements to Chapter 3; Appendix B: Solving the ME to solve the ABM; Appendix C: Specifying transition rates; Index.

  18. Sibling interaction.

    PubMed

    Balsam, Rosemary H

    2013-01-01

    Sibling interactions traditionally were conceived psychoanalytically in "vertical" and parentified oedipal terms and overlooked in their own right, for complicated reasons (Colonna and Newman 1983). Important work has been done to right this, from the 1980s and onward, with conferences and writings. Juliet Mitchell's 2000 and, in particular, her 2003 books, for example, have brought "lateral" sibling relations forcefully to the forefront of insights, especially about sex and violence, with the added interdisciplinary impact of illuminating upheaval in global community interactions as well as having implications for clinicians. A clinical example from the analysis of an adult woman with a ten-years-younger sister will show here how we need both concepts to help us understand complex individual psychic life. The newer "lateral" sibling emphasis, including Mitchell's "Law of the Mother" and "seriality," can be used to inform the older "vertical" take, to enrich the full dimensions of intersubjective oedipal and preoedipal reciprocities that have been foundational in shaping that particular analysand's inner landscape. Some technical recommendations for heightening sensitivity to the import of these dynamics will be offered along the way here, by invoking Hans Loewald's useful metaphor of the analytic situation as theater.

  19. [Pharmacokinetic interactions].

    PubMed

    Arazo Garcés, Piedad; de los Santos Gil, Ignacio

    2013-06-01

    Rilpivirine (RPV) is a nonnucleoside reverse transcriptase inhibitor (NNRTI) that has been approved for use in treatment-naïve patients and which has potent antiviral activity. Its adverse effects profile differs from that of first-generation NNRTs. The pharmacological interactions produced by RPV are due to its effects on the CYP450 system; RPV is a substrate and mild inducer of CYP3A4. Moreover, in vitro, RPV inhibits glycoprotein-P. RPV has clinically significant pharmacological interactions, especially with protease inhibitors (except boosted darunavir and lopinavir) and the NNRTIs efavirenz and nevirapine. Coadministration of RPV with drugs that increase gastric pH, such as omeprazole, or those inducing CYP3A4, such as rifampicin, can significantly reduce RPV concentrations and is contraindicated. The concomitant use of RPV with a CYP3A4 inhibitor (such as clarithromycin) can increase RPV concentrations. Administration of PRV with food is recommended to obtain better absorption and adequate plasma values. Copyright © 2013 Elsevier España, S.L. All rights reserved.

  20. Cosmic Interactions

    NASA Astrophysics Data System (ADS)

    2008-01-01

    An image based on data taken with ESO's Very Large Telescope reveals a triplet of galaxies intertwined in a cosmic dance. ESO PR Photo 02/08 ESO PR Photo 02/08 NGC 7173, 7174, and 7176 The three galaxies, catalogued as NGC 7173 (top), 7174 (bottom right) and 7176 (bottom left), are located 106 million light-years away towards the constellation of Piscis Austrinus (the 'Southern Fish'). NGC 7173 and 7176 are elliptical galaxies, while NGC 7174 is a spiral galaxy with quite disturbed dust lanes and a long, twisted tail. This seems to indicate that the two bottom galaxies - whose combined shape bears some resemblance to that of a sleeping baby - are currently interacting, with NGC 7176 providing fresh material to NGC 7174. Matter present in great quantity around the triplet's members also points to the fact that NGC 7176 and NGC 7173 have interacted in the past. Astronomers have suggested that the three galaxies will finally merge into a giant 'island universe', tens to hundreds of times as massive as our own Milky Way. ESO PR Photo 02/08 ESO PR Photo 02b/08 NGC 7173, 7174, and 7176 The triplet is part of a so-called 'Compact Group', as compiled by Canadian astronomer Paul Hickson in the early 1980s. The group, which is the 90th entry in the catalogue and is therefore known as HCG 90, actually contains four major members. One of them - NGC 7192 - lies above the trio, outside of this image, and is another peculiar spiral galaxy. Compact groups are small, relatively isolated, systems of typically four to ten galaxies in close proximity to one another. Another striking example is Robert's Quartet. Compact groups are excellent laboratories for the study of galaxy interactions and their effects, in particular the formation of stars. As the striking image reveals, there are many other galaxies in the field. Some are distant ones, while others seem to be part of the family. Studies made with other telescopes have indeed revealed that the HCG 90 group contains 16 members

  1. Electroweak interactions

    SciTech Connect

    Bjorken, J.D.

    1980-10-01

    A point of view of the electroweak interaction is presented. It begins phenomenologically and moves in stages toward the conventional gauge theory formalism containing elementary scalar Higgs-fields and then beyond. The purpose in so doing is that the success of the standard SU(2) x U(1) theory in accounting for low energy phenomena need not automatically imply success at high energies. It is deemed unlikely by most theorists that the predicted W/sup + -/ or Z/sup 0/ does not exist or does not have the mass and/or couplings anticipated in the standard model. However, the odds that the standard predictions will work are not 100%. Therefore there is some reason to look at the subject as one would were he forced by a wrong experimental outcome - to go back to fundamentals and ascertain what is the minimal amount of theory necessary to account for the data.

  2. Designing "Interaction": How Do Interaction Design Students Address Interaction?

    ERIC Educational Resources Information Center

    Karlgren, Klas; Ramberg, Robert; Artman, Henrik

    2016-01-01

    Interaction design is usually described as being concerned with interactions with and through artifacts but independent of a specific implementation. Design work has been characterized as a conversation between the designer and the situation and this conversation poses a particular challenge for interaction design as interactions can be elusive…

  3. Designing "Interaction": How Do Interaction Design Students Address Interaction?

    ERIC Educational Resources Information Center

    Karlgren, Klas; Ramberg, Robert; Artman, Henrik

    2016-01-01

    Interaction design is usually described as being concerned with interactions with and through artifacts but independent of a specific implementation. Design work has been characterized as a conversation between the designer and the situation and this conversation poses a particular challenge for interaction design as interactions can be elusive…

  4. Cloud Interactions

    NASA Technical Reports Server (NTRS)

    2004-01-01

    [figure removed for brevity, see original site]

    Released 1 July 2004 The atmosphere of Mars is a dynamic system. Water-ice clouds, fog, and hazes can make imaging the surface from space difficult. Dust storms can grow from local disturbances to global sizes, through which imaging is impossible. Seasonal temperature changes are the usual drivers in cloud and dust storm development and growth.

    Eons of atmospheric dust storm activity has left its mark on the surface of Mars. Dust carried aloft by the wind has settled out on every available surface; sand dunes have been created and moved by centuries of wind; and the effect of continual sand-blasting has modified many regions of Mars, creating yardangs and other unusual surface forms.

    This image was acquired during mid-spring near the North Pole. The linear water-ice clouds are now regional in extent and often interact with neighboring cloud system, as seen in this image. The bottom of the image shows how the interaction can destroy the linear nature. While the surface is still visible through most of the clouds, there is evidence that dust is also starting to enter the atmosphere.

    Image information: VIS instrument. Latitude 68.4, Longitude 258.8 East (101.2 West). 38 meter/pixel resolution.

    Note: this THEMIS visual image has not been radiometrically nor geometrically calibrated for this preliminary release. An empirical correction has been performed to remove instrumental effects. A linear shift has been applied in the cross-track and down-track direction to approximate spacecraft and planetary motion. Fully calibrated and geometrically projected images will be released through the Planetary Data System in accordance with Project policies at a later time.

    NASA's Jet Propulsion Laboratory manages the 2001 Mars Odyssey mission for NASA's Office of Space Science, Washington, D.C. The Thermal Emission Imaging System (THEMIS) was developed by Arizona State University, Tempe, in collaboration

  5. Formation et interaction (Teacher Education and Interaction).

    ERIC Educational Resources Information Center

    Bertocchini, Paola; Costanzo, Edwige

    1989-01-01

    Effective interaction is as important in inservice education programs for language teachers as it is in the foreign language classroom. Techniques are described for improving the quality of interaction in teacher workshops through simulation exercises. (MSE)

  6. PIC: Protein Interactions Calculator

    PubMed Central

    Tina, K. G.; Bhadra, R.; Srinivasan, N.

    2007-01-01

    Interactions within a protein structure and interactions between proteins in an assembly are essential considerations in understanding molecular basis of stability and functions of proteins and their complexes. There are several weak and strong interactions that render stability to a protein structure or an assembly. Protein Interactions Calculator (PIC) is a server which, given the coordinate set of 3D structure of a protein or an assembly, computes various interactions such as disulphide bonds, interactions between hydrophobic residues, ionic interactions, hydrogen bonds, aromatic–aromatic interactions, aromatic–sulphur interactions and cation–π interactions within a protein or between proteins in a complex. Interactions are calculated on the basis of standard, published criteria. The identified interactions between residues can be visualized using a RasMol and Jmol interface. The advantage with PIC server is the easy availability of inter-residue interaction calculations in a single site. It also determines the accessible surface area and residue-depth, which is the distance of a residue from the surface of the protein. User can also recognize specific kind of interactions, such as apolar–apolar residue interactions or ionic interactions, that are formed between buried or exposed residues or near the surface or deep inside. PMID:17584791

  7. PIC: Protein Interactions Calculator.

    PubMed

    Tina, K G; Bhadra, R; Srinivasan, N

    2007-07-01

    Interactions within a protein structure and interactions between proteins in an assembly are essential considerations in understanding molecular basis of stability and functions of proteins and their complexes. There are several weak and strong interactions that render stability to a protein structure or an assembly. Protein Interactions Calculator (PIC) is a server which, given the coordinate set of 3D structure of a protein or an assembly, computes various interactions such as disulphide bonds, interactions between hydrophobic residues, ionic interactions, hydrogen bonds, aromatic-aromatic interactions, aromatic-sulphur interactions and cation-pi interactions within a protein or between proteins in a complex. Interactions are calculated on the basis of standard, published criteria. The identified interactions between residues can be visualized using a RasMol and Jmol interface. The advantage with PIC server is the easy availability of inter-residue interaction calculations in a single site. It also determines the accessible surface area and residue-depth, which is the distance of a residue from the surface of the protein. User can also recognize specific kind of interactions, such as apolar-apolar residue interactions or ionic interactions, that are formed between buried or exposed residues or near the surface or deep inside.

  8. Food and Drug Interactions.

    PubMed

    Choi, Jong Hwan; Ko, Chang Mann

    2017-01-01

    Natural foods and vegetal supplements have recently become increasingly popular for their roles in medicine and as staple foods. This has, however, led to the increased risk of interaction between prescribed drugs and the bioactive ingredients contained in these foods. These interactions range from pharmacokinetic interactions (absorption, distribution, metabolism, and excretion influencing blood levels of drugs) to pharmacodynamic interactions (drug effects). In a quantitative respect, these interactions occur mainly during metabolism. In addition to the systemic metabolism that occurs mainly in the liver, recent studies have focused on the metabolism in the gastrointestinal tract endothelium before absorption. Inhibition of metabolism causes an increase in the blood levels of drugs and could have adverse reactions. The food-drug interactions causing increased blood levels of drugs may have beneficial or detrimental therapeutic effects depending on the intensity and predictability of these interactions. It is therefore important to understand the potential interactions between foods and drugs should and the specific outcomes of such interactions.

  9. Interacting dark sector with transversal interaction

    SciTech Connect

    Chimento, Luis P.; Richarte, Martín G.

    2015-03-26

    We investigate the interacting dark sector composed of dark matter, dark energy, and dark radiation for a spatially flat Friedmann-Robertson-Walker (FRW) background by introducing a three-dimensional internal space spanned by the interaction vector Q and solve the source equation for a linear transversal interaction. Then, we explore a realistic model with dark matter coupled to a scalar field plus a decoupled radiation term, analyze the amount of dark energy in the radiation era and find that our model is consistent with the recent measurements of cosmic microwave background anisotropy coming from Planck along with the future constraints achievable by CMBPol experiment.

  10. Gestalt Interactional Groups

    ERIC Educational Resources Information Center

    Harman, Robert L.; Franklin, Richard W.

    1975-01-01

    Gestalt therapy in groups is not limited to individual work in the presence of an audience. Describes several ways to involve gestalt groups interactionally. Interactions described focus on learning by doing and discovering, and are noninterpretive. (Author/EJT)

  11. Computerized Interactive Harness Engineering

    NASA Technical Reports Server (NTRS)

    Billitti, J. W.

    1985-01-01

    Computerized interactive harness engineering program inexpensive, interactive system for learning and using engineering approach to interconnection systems. Basically data-base system that stores information as files of individual connectors and handles wiring information in circuit groups stored as records.

  12. Interactions between magnetohydrodynamical discontinuities

    SciTech Connect

    Dai, W.; Woodward, P.R. )

    1994-11-01

    Interactions between magnetohydrodynamical (MHD) discontinuities are studied through numerical simulations for the set of one-dimensional MHD equations. The interactions include the impact of a shock on a contact discontinuity, the collision of two shocks, and the catchup of a shock over another shock. The shocks involved in the interactions may be very strong. Each shock in an interaction may be either a fast or a slow shock.

  13. Interactivity: A Forgotten Art?

    ERIC Educational Resources Information Center

    Sims, Rod

    1997-01-01

    This paper promotes further discussion and analysis of interactivity in learning environments and contains a classification of interaction types appropriate for consideration in multimedia settings. Through an examination of related factors associated with navigation and control, a matrix of interactive dimensions is proposed. (Author)

  14. Interactive Reactor Simulation.

    ERIC Educational Resources Information Center

    Nuttall, Herbert E., Jr.; Himmelblau, David M.

    In the field of chemical engineering, interactive process models can simulate the dynamic behavior and analysis of chemical processes. DYFLO was the process simulation program selected as a foundation for development of interactive programs for computer-assisted instruction (CAI) in chemical engineering. Interactive Computing and time sharing…

  15. Dynamic Interactive Learning Systems

    ERIC Educational Resources Information Center

    Sabry, Khaled; Barker, Jeff

    2009-01-01

    This paper reviews and discusses the notions of interactivity and dynamicity of learning systems in relation to information technologies and design principles that can contribute to interactive and dynamic learning. It explores the concept of dynamic interactive learning systems based on the emerging generation of information as part of a…

  16. Global Interaction in Design

    ERIC Educational Resources Information Center

    Bennett, Audrey Grace

    2010-01-01

    Based on a virtual conference, Glide'08 (Global Interaction in Design Education), that brought international design scholars together online, this special issue expands on the topics of cross-cultural communication and design and the technological affordances that support such interaction. The author discusses the need for global interaction in…

  17. Evolving synergetic interactions

    PubMed Central

    Wu, Bin; Arranz, Jordi; Du, Jinming; Zhou, Da; Traulsen, Arne

    2016-01-01

    Cooperators forgo their own interests to benefit others. This reduces their fitness and thus cooperators are not likely to spread based on natural selection. Nonetheless, cooperation is widespread on every level of biological organization ranging from bacterial communities to human society. Mathematical models can help to explain under which circumstances cooperation evolves. Evolutionary game theory is a powerful mathematical tool to depict the interactions between cooperators and defectors. Classical models typically involve either pairwise interactions between individuals or a linear superposition of these interactions. For interactions within groups, however, synergetic effects may arise: their outcome is not just the sum of its parts. This is because the payoffs via a single group interaction can be different from the sum of any collection of two-player interactions. Assuming that all interactions start from pairs, how can such synergetic multiplayer games emerge from simpler pairwise interactions? Here, we present a mathematical model that captures the transition from pairwise interactions to synergetic multiplayer ones. We assume that different social groups have different breaking rates. We show that non-uniform breaking rates do foster the emergence of synergy, even though individuals always interact in pairs. Our work sheds new light on the mechanisms underlying such synergetic interactions. PMID:27466437

  18. The Interactive Learning Toolkit: supporting interactive classrooms

    NASA Astrophysics Data System (ADS)

    Dutta, S.; McCauley, V.; Mazur, E.

    2004-05-01

    Research-based interactive learning techniques have dramatically improved student understanding. We have created the 'Interactive Learning Toolkit' (ILT), a web-based learning management system, to help implement two such pedagogies: Just in Time Teaching and Peer Instruction. Our main goal in developing this toolkit is to save the instructor time and effort and to use technology to facilitate the interaction between the students and the instructor (and between students themselves). After a brief review of both pedagogies, we will demonstrate the many exciting new features of the ILT. We will show how technology can not only implement, but also supplement and improve these pedagogies. We would like acknowdge grants from NSF and DEAS, Harvard University

  19. [Drug-drug interactions: interactions between xenobiotics].

    PubMed

    Haen, E

    2014-04-01

    Drug-drug interactions (DDI) are a major topic in programs for continuous medical education (CME). Many physicians are afraid of being trapped into charges of malpractice; however, DDI cannot be avoided in many cases. They belong to routine medical practice and it is often impossible to avoid them. Moreover, they do not just occur between drugs but between any kind of foreign substance (xenobiotica), such as food (e.g. grapefruit juice, broccoli, barbecue) as well as legal (e.g. tobacco smoke, caffeine and alcohol) and illegal drugs. Therefore, the medical challenge is not just to avoid any interaction. Instead the physician faces the question of how to proceed with drug treatment in the presence of such interactions. Based on the medical education a physician has to judge first of all whether there is a risk for interactions in the prescription being planned for an individual patient. The classification of interactions proposed in this article (PD1-PD4, PK1-PK3) might help as a sort of check list. For more detailed information the physician can then consult one of the many databases available on the internet, such as PSIAConline (http://www.psiac.de) and MediQ (http://www.mediq.ch). Pharmacokinetic interactions can be easily assessed, monitored and controlled by therapeutic drug monitoring (TDM). Besides these tools it is important to keep in mind that nobody knows everything; even physicians do not know everything. So take pride in asking someone who might help and for this purpose AGATE offers a drug information service AID (http://www.amuep-agate.de). Just good for nothing, without being based on any kind of medical approach are computer programs that judge prescriptions without taking into account a patient's individual peculiarities. In case these types of programs produce red exclamation marks or traffic lights to underline their judgment, they might even work in a contrapuntal way by just eliciting insecurity and fear.

  20. The interactive brain hypothesis

    PubMed Central

    Di Paolo, Ezequiel; De Jaegher, Hanne

    2012-01-01

    Enactive approaches foreground the role of interpersonal interaction in explanations of social understanding. This motivates, in combination with a recent interest in neuroscientific studies involving actual interactions, the question of how interactive processes relate to neural mechanisms involved in social understanding. We introduce the Interactive Brain Hypothesis (IBH) in order to help map the spectrum of possible relations between social interaction and neural processes. The hypothesis states that interactive experience and skills play enabling roles in both the development and current function of social brain mechanisms, even in cases where social understanding happens in the absence of immediate interaction. We examine the plausibility of this hypothesis against developmental and neurobiological evidence and contrast it with the widespread assumption that mindreading is crucial to all social cognition. We describe the elements of social interaction that bear most directly on this hypothesis and discuss the empirical possibilities open to social neuroscience. We propose that the link between coordination dynamics and social understanding can be best grasped by studying transitions between states of coordination. These transitions form part of the self-organization of interaction processes that characterize the dynamics of social engagement. The patterns and synergies of this self-organization help explain how individuals understand each other. Various possibilities for role-taking emerge during interaction, determining a spectrum of participation. This view contrasts sharply with the observational stance that has guided research in social neuroscience until recently. We also introduce the concept of readiness to interact to describe the practices and dispositions that are summoned in situations of social significance (even if not interactive). This latter idea links interactive factors to more classical observational scenarios. PMID:22701412

  1. How Interactive Is the Interactive Whiteboard?

    ERIC Educational Resources Information Center

    Quashie, Valerie

    2009-01-01

    An interactive whiteboard (IWB) is simply a surface onto which a computer screen can be displayed, via a projector. It is touch-sensitive and lets one use a pen like a mouse, controlling the computer from the board itself. Everything that can be displayed on a computer can be displayed onto the whiteboard and, if the computer is linked to speakers…

  2. Interactive Whiteboards: Interactive or Just Whiteboards?

    ERIC Educational Resources Information Center

    Northcote, Maria; Mildenhall, Paula; Marshall, Linda; Swan, Paul

    2010-01-01

    Over the last decade, interactive whiteboards have become popular teaching and learning tools, especially in primary school classrooms. Research studies from recent literature report on high levels of student motivation, teacher enthusiasm and whole-school support associated with these technological tools. Much research to date has reported on the…

  3. Beam-Bem interactions

    SciTech Connect

    Kim, Hyung Jin; /Fermilab

    2011-12-01

    In high energy storage-ring colliders, the nonlinear effect arising from beam-beam interactions is a major source that leads to the emittance growth, the reduction of beam life time, and limits the collider luminosity. In this paper, two models of beam-beam interactions are introduced, which are weak-strong and strong-strong beam-beam interactions. In addition, space-charge model is introduced.

  4. Food-drug interactions.

    PubMed

    Bushra, Rabia; Aslam, Nousheen; Khan, Arshad Yar

    2011-03-01

    The effect of drug on a person may be different than expected because that drug interacts with another drug the person is taking (drug-drug interaction), food, beverages, dietary supplements the person is consuming (drug-nutrient/food interaction) or another disease the person has (drug-disease interaction). A drug interaction is a situation in which a substance affects the activity of a drug, i.e. the effects are increased or decreased, or they produce a new effect that neither produces on its own. These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances. Regarding food-drug interactions physicians and pharmacists recognize that some foods and drugs, when taken simultaneously, can alter the body's ability to utilize a particular food or drug, or cause serious side effects. Clinically significant drug interactions, which pose potential harm to the patient, may result from changes in pharmaceutical, pharmacokinetic, or pharmacodynamic properties. Some may be taken advantage of, to the benefit of patients, but more commonly drug interactions result in adverse drug events. Therefore it is advisable for patients to follow the physician and doctors instructions to obtain maximum benefits with least food-drug interactions. The literature survey was conducted by extracting data from different review and original articles on general or specific drug interactions with food. This review gives information about various interactions between different foods and drugs and will help physicians and pharmacists prescribe drugs cautiously with only suitable food supplement to get maximum benefit for the patient.

  5. Food and Drug Interactions

    PubMed Central

    Choi, Jong Hwan; Ko, Chang Mann

    2017-01-01

    Natural foods and vegetal supplements have recently become increasingly popular for their roles in medicine and as staple foods. This has, however, led to the increased risk of interaction between prescribed drugs and the bioactive ingredients contained in these foods. These interactions range from pharmacokinetic interactions (absorption, distribution, metabolism, and excretion influencing blood levels of drugs) to pharmacodynamic interactions (drug effects). In a quantitative respect, these interactions occur mainly during metabolism. In addition to the systemic metabolism that occurs mainly in the liver, recent studies have focused on the metabolism in the gastrointestinal tract endothelium before absorption. Inhibition of metabolism causes an increase in the blood levels of drugs and could have adverse reactions. The food-drug interactions causing increased blood levels of drugs may have beneficial or detrimental therapeutic effects depending on the intensity and predictability of these interactions. It is therefore important to understand the potential interactions between foods and drugs should and the specific outcomes of such interactions. PMID:28261555

  6. Two interacting Hofstadter butterflies

    SciTech Connect

    Barelli, A.; Bellissard, J.; Jacquod, P.; Shepelyansky, D.L.

    1997-04-01

    The problem of two interacting particles in a quasiperiodic potential is addressed. Using analytical and numerical methods, we explore the spectral properties and eigenstates structure from the weak to the strong interaction case. More precisely, a semiclassical approach based on noncommutative geometry techniques is used to understand the intricate structure of such a spectrum. An interaction induced localization effect is furthermore emphasized. We discuss the application of our results on a two-dimensional model of two particles in a uniform magnetic field with on-site interaction. {copyright} {ital 1997} {ital The American Physical Society}

  7. The Science of Interaction

    SciTech Connect

    Pike, William A.; Stasko, John T.; Chang, Remco; O'Connell, Theresa

    2009-09-23

    There is a growing recognition with the visual analytics community that interaction and inquiry are inextricable. It is through the interactive manipulation of a visual interface – the analytic discourse – that knowledge is constructed, tested, refined, and shared. This paper reflects on the interaction challenges raised in the original visual analytics research and development agenda and further explores the relationship between interaction and cognition. It identifies recent exemplars of visual analytics research that have made substantive progress toward the goals of a true science of interaction, which must include theories and testable premises about the most appropriate mechanisms for human-information interaction. Six areas for further work are highlighted as those among the highest priorities for the next five years of visual analytics research: ubiquitous, embodied interaction; capturing user intentionality; knowledge-based interfaces; principles of design and perception; collaboration; and interoperability. Ultimately, the goal of a science of interaction is to support the visual analytics community through the recognition and implementation of best practices in the representation of and interaction with visual displays.

  8. Gender interactions and success.

    PubMed

    Wiggins, Carla; Peterson, Teri

    2004-01-01

    Does gender by itself, or does gender's interaction with career variables, better explain the difference between women and men's careers in healthcare management? US healthcare managers were surveyed regarding career and personal experiences. Gender was statistically interacted with explanatory variables. Multiple regression with backwards selection systematically removed non-significant variables. All gender interaction variables were non-significant. Much of the literature proposes that work and career factors impact working women differently than working men. We find that while gender alone is a significant predictor of income, it does not significantly interact with other career variables.

  9. Reconceptualizing sex, brain and psychopathology: interaction, interaction, interaction

    PubMed Central

    Joel, D; Yankelevitch-Yahav, R

    2014-01-01

    In recent years there has been a growing recognition of the influence of sex on brain structure and function, and in relation, on the susceptibility, prevalence and response to treatment of psychiatric disorders. Most theories and descriptions of the effects of sex on the brain are dominated by an analogy to the current interpretation of the effects of sex on the reproductive system, according to which sex is a divergence system that exerts a unitary, overriding and serial effect on the form of other systems. We shortly summarize different lines of evidence that contradict aspects of this analogy. The new view that emerges from these data is of sex as a complex system whose different components interact with one another and with other systems to affect body and brain. The paradigm shift that this understanding calls for is from thinking of sex in terms of sexual dimorphism and sex differences, to thinking of sex in terms of its interactions with other factors and processes. Our review of data obtained from animal models of psychopathology clearly reveals the need for such a paradigmatic shift, because in the field of animal behaviour whether a sex difference exists and its direction depend on the interaction of many factors including, species, strain, age, specific test employed and a multitude of environmental factors. We conclude by explaining how the new conceptualization can account for sex differences in psychopathology. Linked Articles This article is part of a themed section on Animal Models in Psychiatry Research. To view the other articles in this section visit http://dx.doi.org/10.1111/bph.2014.171.issue-20 PMID:24758640

  10. Drug-nutrient interactions.

    PubMed

    Chan, Lingtak-Neander

    2013-07-01

    Drug-nutrient interactions are defined as physical, chemical, physiologic, or pathophysiologic relationships between a drug and a nutrient. The causes of most clinically significant drug-nutrient interactions are usually multifactorial. Failure to identify and properly manage drug-nutrient interactions can lead to very serious consequences and have a negative impact on patient outcomes. Nevertheless, with thorough review and assessment of the patient's history and treatment regimens and a carefully executed management strategy, adverse events associated with drug-nutrient interactions can be prevented. Based on the physiologic sequence of events after a drug or a nutrient has entered the body and the mechanism of interactions, drug-nutrient interactions can be categorized into 4 main types. Each type of interaction can be managed using similar strategies. The existing data that guide the clinical management of most drug-nutrient interactions are mostly anecdotal experience, uncontrolled observations, and opinions, whereas the science in understanding the mechanism of drug-nutrient interactions remains limited. The challenge for researchers and clinicians is to increase both basic and higher level clinical research in this field to bridge the gap between the science and practice. The research should aim to establish a better understanding of the function, regulation, and substrate specificity of the nutrient-related enzymes and transport proteins present in the gastrointestinal tract, as well as assess how the incidence and management of drug-nutrient interactions can be affected by sex, ethnicity, environmental factors, and genetic polymorphisms. This knowledge can help us develop a true personalized medicine approach in the prevention and management of drug-nutrient interactions.

  11. Normal Shock Vortex Interaction

    DTIC Science & Technology

    2003-03-01

    Figure 9: Breakdown map for normal-shock vortex-interaction. References [1] O. Thomer, W. Schroder and M. Meinke , Numerical Simulation of Normal...and Oblique-Shock Vortex Interaction, ZAMM Band 80, Sub. 1, pp. 181-184, 2000. [2] O. Thomer, E. Krause, W. Schroder and M. Meinke , Computational

  12. Let Social Interaction Flourish

    ERIC Educational Resources Information Center

    Case, Anny Fritzen

    2016-01-01

    The author describes lessons learned--through a high school project that grouped English language learners with native speakers to create a video--about ways to foster respectful, productive interaction among English learners and peers who are native speakers. The potential benefits of students who are just learning English interacting socially…

  13. Interactive Presentation of Content

    ERIC Educational Resources Information Center

    Magdin, Martin; Turcáni, Milan; Vrábel, Marek

    2009-01-01

    In the paper we discus about design of universal environment for solution of creating effective multimedia applications with accent on the implementation of interactive elements with the possibility of using the adaptive systems (AS). We also discuss about possibilities of offline presentation of this interactive multimedia adaptive animations…

  14. Interaction Analysis in MANOVA.

    ERIC Educational Resources Information Center

    Betz, M. Austin

    Simultaneous test procedures (STPS for short) in the context of the unrestricted full rank general linear multivariate model for population cell means are introduced and utilized to analyze interactions in factorial designs. By appropriate choice of an implying hypothesis, it is shown how to test overall main effects, interactions, simple main,…

  15. Storyboarding Multimedia Interactions.

    ERIC Educational Resources Information Center

    Martin, Linda C.

    2000-01-01

    Understanding how to include interactivity when designing multimedia-based training (MBT) storyboards is a major key for a successful MBT. Discusses the basic formats of interactions and when to use each format. Describes how to storyboard and areas to address, including: the display area, prompts, branching, programming and graphics notes,…

  16. Visualizing Dispersion Interactions

    ERIC Educational Resources Information Center

    Gottschalk, Elinor; Venkataraman, Bhawani

    2014-01-01

    An animation and accompanying activity has been developed to help students visualize how dispersion interactions arise. The animation uses the gecko's ability to walk on vertical surfaces to illustrate how dispersion interactions play a role in macroscale outcomes. Assessment of student learning reveals that students were able to develop…

  17. Storyboarding Multimedia Interactions.

    ERIC Educational Resources Information Center

    Martin, Linda C.

    2000-01-01

    Understanding how to include interactivity when designing multimedia-based training (MBT) storyboards is a major key for a successful MBT. Discusses the basic formats of interactions and when to use each format. Describes how to storyboard and areas to address, including: the display area, prompts, branching, programming and graphics notes,…

  18. Interactive Visualization of Dependencies

    ERIC Educational Resources Information Center

    Moreno, Camilo Arango; Bischof, Walter F.; Hoover, H. James

    2012-01-01

    We present an interactive tool for browsing course requisites as a case study of dependency visualization. This tool uses multiple interactive visualizations to allow the user to explore the dependencies between courses. A usability study revealed that the proposed browser provides significant advantages over traditional methods, in terms of…

  19. Interactive Visualization of Dependencies

    ERIC Educational Resources Information Center

    Moreno, Camilo Arango; Bischof, Walter F.; Hoover, H. James

    2012-01-01

    We present an interactive tool for browsing course requisites as a case study of dependency visualization. This tool uses multiple interactive visualizations to allow the user to explore the dependencies between courses. A usability study revealed that the proposed browser provides significant advantages over traditional methods, in terms of…

  20. University-industry interaction

    NASA Technical Reports Server (NTRS)

    Hastings, Daniel E.

    1990-01-01

    It is posited that university industry interaction is highly desirable from the viewpoint of the long term economic development of the country as well as being desirable for the Space Grant Programs. The present and future possible interactions are reviewed for the three university levels namely, undergraduate, graduate, and faculty research.

  1. Interactive TV: The Sequel.

    ERIC Educational Resources Information Center

    Brown, Eric

    1998-01-01

    Examines the future of interactive TV where consumers navigate the Internet on their TVs with WebTV set-top boxes. Focuses on competition between cable companies and computer and consumer electronics companies. Highlights nine companies and partnerships developing interactive hardware and services. (PEN)

  2. Visualizing Dispersion Interactions

    ERIC Educational Resources Information Center

    Gottschalk, Elinor; Venkataraman, Bhawani

    2014-01-01

    An animation and accompanying activity has been developed to help students visualize how dispersion interactions arise. The animation uses the gecko's ability to walk on vertical surfaces to illustrate how dispersion interactions play a role in macroscale outcomes. Assessment of student learning reveals that students were able to develop…

  3. Let Social Interaction Flourish

    ERIC Educational Resources Information Center

    Case, Anny Fritzen

    2016-01-01

    The author describes lessons learned--through a high school project that grouped English language learners with native speakers to create a video--about ways to foster respectful, productive interaction among English learners and peers who are native speakers. The potential benefits of students who are just learning English interacting socially…

  4. Interaction Online: A Reevaluation

    ERIC Educational Resources Information Center

    Battalio, John

    2007-01-01

    Instructors commonly assume that the successful online course must replicate its live counterpart by including a variety of interactions among student, instructor, and computer. Given the changing lifestyles prompted by an evolving Internet, an increasing student need for autonomy, and student learning styles, highly interactive courses may not…

  5. Elementary particle interactions

    SciTech Connect

    Bugg, W.M.; Condo, G.T.; Handler, T.; Hart, E.L.; Ward, B.F.L.; Close, F.E.; Christophorou, L.G.

    1990-10-01

    This report discusses freon bubble chamber experiments exposed to {mu}{sup +} and neutrinos, photon-proton interactions; shower counter simulations; SLD detectors at the Stanford Linear Collider, and the detectors at the Superconducting Super Collider; elementary particle interactions; physical properties of dielectric materials used in High Energy Physics detectors; and Nuclear Physics. (LSP)

  6. Electromagnetic cellular interactions.

    PubMed

    Cifra, Michal; Fields, Jeremy Z; Farhadi, Ashkan

    2011-05-01

    Chemical and electrical interaction within and between cells is well established. Just the opposite is true about cellular interactions via other physical fields. The most probable candidate for an other form of cellular interaction is the electromagnetic field. We review theories and experiments on how cells can generate and detect electromagnetic fields generally, and if the cell-generated electromagnetic field can mediate cellular interactions. We do not limit here ourselves to specialized electro-excitable cells. Rather we describe physical processes that are of a more general nature and probably present in almost every type of living cell. The spectral range included is broad; from kHz to the visible part of the electromagnetic spectrum. We show that there is a rather large number of theories on how cells can generate and detect electromagnetic fields and discuss experimental evidence on electromagnetic cellular interactions in the modern scientific literature. Although small, it is continuously accumulating.

  7. Spacelab user interaction

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The results of the third and final phase of a study undertaken to define means of optimizing the Spacelab experiment data system by interactively manipulating the flow of data were presented. A number of payload applicable interactive techniques and an integrated interaction system for each of two possible payloads are described. These interaction systems have been functionally defined and are accompanied with block diagrams, hardware specifications, software sizing and speed requirements, operational procedures and cost/benefits analysis data for both onboard and ground based system elements. It is shown that accrued benefits are attributable to a reduction in data processing costs obtained by, generally, a considerable reduction in the quantity of data that might otherwise be generated without interaction. One other additional anticipated benefit includes the increased scientific value obtained by the quicker return of all useful data.

  8. Venus: Interaction with Solar Wind

    NASA Astrophysics Data System (ADS)

    Russell, C.; Luhmann, J.; Murdin, P.

    2002-07-01

    The solar wind interaction with VENUS provides the archetypal interaction of a flowing magnetized PLASMA with a PLANETARY IONOSPHERE. Mars interacts with the solar wind in much the same way as does Venus, while the rotating plasma in the Saturnian magnetosphere is believed to interact similarly with its moon, Titan (see SATURN: MAGNETOSPHERE INTERACTION WITH TITAN). The interaction of the Jovian ...

  9. Cefuroxime antacid interactions.

    PubMed

    Sultana, N; Mubeen, T; Arayne, M S; Ifzal, R

    2001-01-01

    Cefuroxime sodium a second generation semi-synthetic cephalosporin is effective for treating meningitis, lower respiratory tract infections, gonorrhea, bone and joint infections and is approved for surgical prophylaxis. There are number of synergistic and as well as antagonistic drug interactions reported for this antibiotic. Withstanding to gastric irritations caused by this antibiotic, antacids may possibly be co-administered with cefuroxime, which may result in severe adverse drug interaction. The present work describes the effect of magnesium carbonate, magnesium hydroxide, magnesium trisilicate, megaldrate powder, sodium bicarbonate, aluminum oxide and simethicone suspension on the in vitro availability of cefuroxime sodium. The mechanism of interaction between antibiotic and antacids was also studied.

  10. Early Interactive Emotional Development

    PubMed Central

    Messinger, Daniel S.; Mahoor, Mohammad H.; Cadavid, Steven; Chow, Sy-Miin; Cohn, Jeffrey F.

    2010-01-01

    Early infant emotional development concerns the interactive emergence of emotional states that motivate approach and withdrawal. These are indexed by different patterns of infant facial expressions, vocalization, and gazing that emerge within parent-infant interactions in the first 10 months of life. Specifically, the interface of a limited number of interactive parameters creates complex real-time patterns which change over developmental time. These phenomena are described below using techniques from our laboratory such as statistical simulations, continuous ratings, and computer vision modeling. PMID:21804955

  11. Adverse Drug Interactions

    PubMed Central

    Becker, Daniel E.

    2011-01-01

    The potential for interactions with current medications should always be considered when administering or prescribing any drug. Considering the staggering number of drugs patients may be taking, this task can be daunting. Fortunately, drug classes employed in dental practice are relatively few in number and therapy is generally brief in duration. While this reduces the volume of potential interactions, there are still a significant number to be considered. This article will review basic principles of drug interactions and highlight those of greatest concern in dental practice. PMID:21410363

  12. The ADAMS interactive interpreter

    SciTech Connect

    Rietscha, E.R.

    1990-12-17

    The ADAMS (Advanced DAta Management System) project is exploring next generation database technology. Database management does not follow the usual programming paradigm. Instead, the database dictionary provides an additional name space environment that should be interactively created and tested before writing application code. This document describes the implementation and operation of the ADAMS Interpreter, an interactive interface to the ADAMS data dictionary and runtime system. The Interpreter executes individual statements of the ADAMS Interface Language, providing a fast, interactive mechanism to define and access persistent databases. 5 refs.

  13. Interactive Design Activism

    NASA Astrophysics Data System (ADS)

    Goulev, Petar; Farrer, Joan

    The following sections are included: * Introduction * Computers and Human Well-being * To Fuzzy or Yes (No)! * Interactive Design Activism * Sensing the Sun * Personalised Public Health Advice * Modifying Human Behaviour * Transdisciplinarity, Knowledge Transfer and Multi-domain

  14. Electromagnetic and Weak Interactions

    NASA Astrophysics Data System (ADS)

    Salam, A.; Ward, J. C.

    One of the recurrent dreams in elementary particles physics is that of a possible fundamental synthesis between electro-magnetism and weak interactions [1]. The idea has its origin in the following shared characteristics…

  15. Chasing Ecological Interactions.

    PubMed

    Jordano, Pedro

    2016-09-01

    Basic research on biodiversity has concentrated on individual species-naming new species, studying distribution patterns, and analyzing their evolutionary relationships. Yet biodiversity is more than a collection of individual species; it is the combination of biological entities and processes that support life on Earth. To understand biodiversity we must catalog it, but we must also assess the ways species interact with other species to provide functional support for the Tree of Life. Ecological interactions may be lost well before the species involved in those interactions go extinct; their ecological functions disappear even though they remain. Here, I address the challenges in studying the functional aspects of species interactions and how basic research is helping us address the fast-paced extinction of species due to human activities.

  16. Atomic & Molecular Interactions

    SciTech Connect

    2002-07-12

    The Gordon Research Conference (GRC) on Atomic & Molecular Interactions was held at Roger Williams University, Bristol, RI. Emphasis was placed on current unpublished research and discussion of the future target areas in this field.

  17. Interactive Science on Mars

    NASA Astrophysics Data System (ADS)

    Mercer, C. R.; Landis, G. A.

    2017-02-01

    Swarms of small citizen-driven rovers can conduct Mars surface science missions. Transportation and communication technology needed for human exploration can enable this new interactive science mission architecture.

  18. Chasing Ecological Interactions

    PubMed Central

    2016-01-01

    Basic research on biodiversity has concentrated on individual species—naming new species, studying distribution patterns, and analyzing their evolutionary relationships. Yet biodiversity is more than a collection of individual species; it is the combination of biological entities and processes that support life on Earth. To understand biodiversity we must catalog it, but we must also assess the ways species interact with other species to provide functional support for the Tree of Life. Ecological interactions may be lost well before the species involved in those interactions go extinct; their ecological functions disappear even though they remain. Here, I address the challenges in studying the functional aspects of species interactions and how basic research is helping us address the fast-paced extinction of species due to human activities. PMID:27631692

  19. Interactive Office user's manual

    NASA Technical Reports Server (NTRS)

    Montgomery, Edward E.; Lowers, Benjamin; Nabors, Terri L.

    1990-01-01

    Given here is a user's manual for Interactive Office (IO), an executive office tool for organization and planning, written specifically for Macintosh. IO is a paperless management tool to automate a related group of individuals into one productive system.

  20. Interactive spectra demonstration

    NASA Astrophysics Data System (ADS)

    Palmquist, Bruce C.

    2002-03-01

    This report describes an interactive demonstration to help students qualitatively understand emission, continuous, and absorption spectra. Students throw colored balls at a person representing an electron that can move between discrete energy levels.

  1. Grapefruit and drug interactions.

    PubMed

    2012-12-01

    Since the late 1980s, grapefruit juice has been known to affect the metabolism of certain drugs. Several serious adverse effects involving drug interactions with grapefruit juice have been published in detail. The components of grapefruit juice vary considerably depending on the variety, maturity and origin of the fruit, local climatic conditions, and the manufacturing process. No single component accounts for all observed interactions. Other grapefruit products are also occasionally implicated, including preserves, lyophylised grapefruit juice, powdered whole grapefruit, grapefruit seed extract, and zest. Clinical reports of drug interactions with grapefruit juice are supported by pharmacokinetic studies, each usually involving about 10 healthy volunteers, in which the probable clinical consequences were extrapolated from the observed plasma concentrations. Grapefruit juice inhibits CYP3A4, the cytochrome P450 isoenzyme most often involved in drug metabolism. This increases plasma concentrations of the drugs concerned, creating a risk of overdose and dose-dependent adverse effects. Grapefruit juice also inhibits several other cytochrome P450 isoenzymes, but they are less frequently implicated in interactions with clinical consequences. Drugs interacting with grapefruit and inducing serious clinical consequences (confirmed or very probable) include: immunosuppressants, some statins, benzodiazepines, most calcium channel blockers, indinavir and carbamazepine. There are large inter-individual differences in enzyme efficiency. Along with the variable composition of grapefruit juice, this makes it difficult to predict the magnitude and clinical consequences of drug interactions with grapefruit juice in a given patient. There is increasing evidence that transporter proteins such as organic anion transporters and P-glycoprotein are involved in interactions between drugs and grapefruit juice. In practice, numerous drugs interact with grapefruit juice. Although only a few

  2. Beam-Material Interaction

    SciTech Connect

    Mokhov, N. V.; Cerutti, F.

    2016-01-01

    Th is paper is motivated by the growing importance of better understanding of the phenomena and consequences of high-intensity energetic particle beam interactions with accelerator, generic target, and detector components. It reviews the principal physical processes of fast-particle interactions with matter, effects in materials under irradiation, materials response, related to component lifetime and performance, simulation techniques, and methods of mitigating the impact of radiation on the components and environment in challenging current and future applications.

  3. LASER-tissue interactions.

    PubMed

    Carroll, Lisa; Humphreys, Tatyana R

    2006-01-01

    As new laser devices continue to emerge, it becomes increasingly important for the clinical dermatologist to understand the basic principles behind their operation. A fundamental understanding of how lasers interact with tissue will enable the physician to choose the most appropriate laser for a given clinical situation. Although the physical laws guiding laser design are vastly complex, the fundamental principles of laser-tissue interaction can be summarized as they are applicable to the clinician.

  4. An Interactive Plotting Routine

    NASA Technical Reports Server (NTRS)

    Bowdish, D. W.

    1985-01-01

    Routine called CRTRPM meets needs of applications programer to plot data in interactive environment on Tektronix graphics terminal. CRTRPM designed specifically for applications where data is viewed and responded to at terminal. CRTRPM produces from one to four grids on terminal screen at one time, with from one to ten plots of X-Y data on each grid. CRTRPM written in FORTRAN V for interactive execution.

  5. PIA: ISOPHOT Interactive Analysis

    NASA Astrophysics Data System (ADS)

    Gabriel, Carlos; Acosta, Jose; Heinrichsen, Ingolf; Skaley, Detlef; Tai, Wai Ming; Morris, Huw; Merluzzi, Paola

    2014-08-01

    ISOPHOT is one of the instruments on board the Infrared Space Observatory (ISO). ISOPHOT Interactive Analysis (PIA) is a scientific and calibration interactive data analysis tool for ISOPHOT data reduction. Written in IDL under Xwindows, PIA offers a full context sensitive graphical interface for retrieving, accessing and analyzing ISOPHOT data. It is available in two nearly identical versions; a general observers version omits the calibration sequences.

  6. Replicators with Hebb interactions

    NASA Astrophysics Data System (ADS)

    de Oliveira, V. M.

    2003-01-01

    We do an analytical study of the statistical properties of an ecosystem composed of species that are coupled via pairwise interactions that are given by the Hebb rule and have deterministic self-interactions u. In the model each species is characterized by an infinite set of p = αN traits. As one of our main results, we observe that the ecosystem becomes less cooperative as the complexity of species (number of traits) is increased.

  7. Interactive DIF Generator

    NASA Technical Reports Server (NTRS)

    Preheim, Larry E.; Amy, Laraine; Young, Jimmie D.

    1993-01-01

    Interactive DIF Generator (IDG) computer program serves as utility to generate and manipulate directory interchange format (DIF) files. Creates and updates DIF files, sent to NASA's Master Directory, also referred to as International Global Change Directory at Goddard Space Flight Center. Many government and university data systems use Master Directory to advertise availability of research data. IDG is interactive software tool and requires mouse or trackball to operate. Written in C language.

  8. Vortice-propeller interaction

    NASA Astrophysics Data System (ADS)

    Hemon, Alain; Huberson, Serge

    1989-08-01

    The interactions between a ship's propeller blades and the boundary layer created by the ship are investigated. A finite element calculation method based on Navier-Stokes equation is developed. The application of an k-epsilon turbulence model for improving the analysis is considered. The flow azimuthal homogenization hypothesis is applied and leads to an accurate evaluation of the propeller performances. The unsteady effects generated by the interaction between the propeller blades and the vortices are analyzed.

  9. Interactive Plotting Program

    NASA Technical Reports Server (NTRS)

    Moore, Judith G.

    1988-01-01

    Interactive Plotting Program (IAP) provides fast and easy method of plotting data in presentable format. Extensive plot editing done with various IAP commands, typed interactively from terminal or read from batch command files. Ability to redirect output to variety of devices enables user to tailor plots with graphics terminal before printing. Designed to allow addition or deletion of code for any type of terminal or plotting device. Written in FORTRAN 77 and Assembler.

  10. Food-drug interactions.

    PubMed

    Schmidt, Lars E; Dalhoff, Kim

    2002-01-01

    Interactions between food and drugs may inadvertently reduce or increase the drug effect. The majority of clinically relevant food-drug interactions are caused by food-induced changes in the bioavailability of the drug. Since the bioavailability and clinical effect of most drugs are correlated, the bioavailability is an important pharmacokinetic effect parameter. However, in order to evaluate the clinical relevance of a food-drug interaction, the impact of food intake on the clinical effect of the drug has to be quantified as well. As a result of quality review in healthcare systems, healthcare providers are increasingly required to develop methods for identifying and preventing adverse food-drug interactions. In this review of original literature, we have tried to provide both pharmacokinetic and clinical effect parameters of clinically relevant food-drug interactions. The most important interactions are those associated with a high risk of treatment failure arising from a significantly reduced bioavailability in the fed state. Such interactions are frequently caused by chelation with components in food (as occurs with alendronic acid, clodronic acid, didanosine, etidronic acid, penicillamine and tetracycline) or dairy products (ciprofloxacin and norfloxacin), or by other direct interactions between the drug and certain food components (avitriptan, indinavir, itraconazole solution, levodopa, melphalan, mercaptopurine and perindopril). In addition, the physiological response to food intake, in particular gastric acid secretion, may reduce the bioavailability of certain drugs (ampicillin, azithromycin capsules, didanosine, erythromycin stearate or enteric coated, and isoniazid). For other drugs, concomitant food intake may result in an increase in drug bioavailability either because of a food-induced increase in drug solubility (albendazole, atovaquone, griseofulvin, isotretinoin, lovastatin, mefloquine, saquinavir and tacrolimus) or because of the secretion of

  11. Towards interactive narrative medicine.

    PubMed

    Cavazza, Marc; Charles, Fred

    2013-01-01

    Interactive Storytelling technologies have attracted significant interest in the field of simulation and serious gaming for their potential to provide a principled approach to improve user engagement in training scenarios. In this paper, we explore the use of Interactive Storytelling to support Narrative Medicine as a reflective practice. We describe a workflow for the generation of virtual narratives from high-level descriptions of patients' experiences as perceived by physicians, which can help to objectivize such perceptions and support various forms of analysis.

  12. Flank solar wind interaction

    NASA Technical Reports Server (NTRS)

    Moses, Stewart L.; Greenstadt, Eugene W.; Coroniti, Ferdinand V.

    1994-01-01

    In this report we will summarize the results of the work performed under the 'Flank Solar Wind Interaction' investigation in support of NASA's Space Physics Guest Investigator Program. While this investigation was focused on the interaction of the Earth's magnetosphere with the solar wind as observed by instruments on the International Sun-Earth Explorer (ISEE) 3 spacecraft, it also represents the culmination of decades of research performed by scientists at TRW on the rich phenomenology of collisionless shocks in space.

  13. Human-machine interactions

    DOEpatents

    Forsythe, J. Chris; Xavier, Patrick G.; Abbott, Robert G.; Brannon, Nathan G.; Bernard, Michael L.; Speed, Ann E.

    2009-04-28

    Digital technology utilizing a cognitive model based on human naturalistic decision-making processes, including pattern recognition and episodic memory, can reduce the dependency of human-machine interactions on the abilities of a human user and can enable a machine to more closely emulate human-like responses. Such a cognitive model can enable digital technology to use cognitive capacities fundamental to human-like communication and cooperation to interact with humans.

  14. Interaction with Machine Improvisation

    NASA Astrophysics Data System (ADS)

    Assayag, Gerard; Bloch, George; Cont, Arshia; Dubnov, Shlomo

    We describe two multi-agent architectures for an improvisation oriented musician-machine interaction systems that learn in real time from human performers. The improvisation kernel is based on sequence modeling and statistical learning. We present two frameworks of interaction with this kernel. In the first, the stylistic interaction is guided by a human operator in front of an interactive computer environment. In the second framework, the stylistic interaction is delegated to machine intelligence and therefore, knowledge propagation and decision are taken care of by the computer alone. The first framework involves a hybrid architecture using two popular composition/performance environments, Max and OpenMusic, that are put to work and communicate together, each one handling the process at a different time/memory scale. The second framework shares the same representational schemes with the first but uses an Active Learning architecture based on collaborative, competitive and memory-based learning to handle stylistic interactions. Both systems are capable of processing real-time audio/video as well as MIDI. After discussing the general cognitive background of improvisation practices, the statistical modelling tools and the concurrent agent architecture are presented. Then, an Active Learning scheme is described and considered in terms of using different improvisation regimes for improvisation planning. Finally, we provide more details about the different system implementations and describe several performances with the system.

  15. Embedded human computer interaction.

    PubMed

    Baber, Christopher; Baumann, Konrad

    2002-05-01

    In this paper, human interaction with embedded or ubiquitous technology is considered. The techniques focus on the use of what might be termed "everyday" objects and actions as a means of controlling (or otherwise interacting with) technology. While this paper is not intended to be an exhaustive review, it does present a view of the immediate future of human-computer interaction (HCI) in which users move beyond the desktop to where interacting with technology becomes merged with other activity. At one level this places HCI in the context of other forms of personal and domestic technologies. At another level, this raises questions as to how people will interact with technologies of the future. Until now, HCI had often relied on people learning obscure command sets or learning to recognise words and objects on their computer screen. The most significant advance in HCI (the invention of the WIMP interface) is already some 40 years old. Thus, the future of HCI might be one in which people are encouraged (or at least allowed) to employ the skills that they have developed during their lives in order to interact with technology, rather than being forced to learn and perfect new skills.

  16. Sperm-egg interaction.

    PubMed

    Evans, Janice P

    2012-01-01

    A crucial step of fertilization is the sperm-egg interaction that allows the two gametes to fuse and create the zygote. In the mouse, CD9 on the egg and IZUMO1 on the sperm stand out as critical players, as Cd9(-/-) and Izumo1(-/-) mice are healthy but infertile or severely subfertile due to defective sperm-egg interaction. Moreover, work on several nonmammalian organisms has identified some of the most intriguing candidates implicated in sperm-egg interaction. Understanding of gamete membrane interactions is advancing through characterization of in vivo and in vitro fertilization phenotypes, including insights from less robust phenotypes that highlight potential supporting (albeit not absolutely essential) players. An emerging theme is that there are varied roles for gamete molecules that participate in sperm-egg interactions. Such roles include not only functioning as fusogens, or as adhesion molecules for the opposite gamete, but also functioning through interactions in cis with other proteins to regulate membrane order and functionality.

  17. History of Weak Interactions

    DOE R&D Accomplishments Database

    Lee, T. D.

    1970-07-01

    While the phenomenon of beta-decay was discovered near the end of the last century, the notion that the weak interaction forms a separate field of physical forces evolved rather gradually. This became clear only after the experimental discoveries of other weak reactions such as muon-decay, muon-capture, etc., and the theoretical observation that all these reactions can be described by approximately the same coupling constant, thus giving rise to the notion of a universal weak interaction. Only then did one slowly recognize that the weak interaction force forms an independent field, perhaps on the same footing as the gravitational force, the electromagnetic force, and the strong nuclear and sub-nuclear forces.

  18. Molecular interaction databases.

    PubMed

    Orchard, Sandra

    2012-05-01

    Molecular interaction databases are playing an ever more important role in our understanding of the biology of the cell. An increasing number of resources exist to provide these data and many of these have adopted the controlled vocabularies and agreed-upon standardised data formats produced by the Molecular Interaction workgroup of the Human Proteome Organization Proteomics Standards Initiative (HUPO PSI-MI). Use of these standards allows each resource to establish PSI Common QUery InterfaCe (PSICQUIC) service, making data from multiple resources available to the user in response to a single query. This cooperation between databases has been taken a stage further, with the establishment of the International Molecular Exchange (IMEx) consortium which aims to maximise the curation power of numerous data resources, and provide the user with a non-redundant, consistently annotated set of interaction data. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. Interactions of anabolic steroids.

    PubMed

    Kopera, H

    1993-01-01

    Drug-drug interactions, or interference between drugs and other treatments, depend on many factors and are therefore difficult to predict. However, a number are clearly established in the case of anabolic-androgenic steroids. The beneficial interactions between anabolic steroids and radiotherapy or cytostatic drugs respectively are of therapeutic value. Adjuvant treatment with anabolic compounds in patients undergoing radiation and/or cytostatic therapy is beneficial because it can prevent or reduce depression of erythropoiesis, granulopoiesis and thrombopoiesis. It also diminishes protein catabolism, supports recovery, improves the general condition of the patient and minimizes radiation sickness. Potentially adverse interactions with anabolic steroids must be expected in the case of oral anticoagulants and antidiabetic drugs, since sensitivity to each of the latter is increased. This makes it particularly advisable to monitor patients receiving either oral anticoagulants or antidiabetic treatment concurrently with anabolic drugs.

  20. Dike/Drift Interactions

    SciTech Connect

    E. Gaffiney

    2004-11-23

    This report presents and documents the model components and analyses that represent potential processes associated with propagation of a magma-filled crack (dike) migrating upward toward the surface, intersection of the dike with repository drifts, flow of magma in the drifts, and post-magma emplacement effects on repository performance. The processes that describe upward migration of a dike and magma flow down the drift are referred to as the dike intrusion submodel. The post-magma emplacement processes are referred to as the post-intrusion submodel. Collectively, these submodels are referred to as a conceptual model for dike/drift interaction. The model components and analyses of the dike/drift interaction conceptual model provide the technical basis for assessing the potential impacts of an igneous intrusion on repository performance, including those features, events, and processes (FEPs) related to dike/drift interaction (Section 6.1).

  1. Propeller tip vortex interactions

    NASA Technical Reports Server (NTRS)

    Johnston, Robert T.; Sullivan, John P.

    1990-01-01

    Propeller wakes interacting with aircraft aerodynamic surfaces are a source of noise and vibration. For this reason, flow visualization work on the motion of the helical tip vortex over a wing and through the second stage of a counterrotation propeller (CRP) has been pursued. Initially, work was done on the motion of a propeller helix as it passes over the center of a 9.0 aspect ratio wing. The propeller tip vortex experiences significant spanwise displacements when passing across a lifting wing. A stationary propeller blade or stator was installed behind the rotating propeller to model the blade vortex interaction in a CRP. The resulting vortex interaction was found to depend on the relative vortex strengths and vortex sign.

  2. Carotenoid-Protein Interactions

    NASA Astrophysics Data System (ADS)

    Britton, George; Helliwell, John R.

    Chapter 5 shows that the aggregation of carotenoid molecules can have a profound effect on their properties and hence their functioning in biological systems. Another important influence is the interaction between carotenoids and other molecules. The way that interactions of carotenoids with lipid bilayers influence the structure and properties of membranes and membrane-asociated processes is discussed in Chapter 10, and the aggregation of carotenoid molecules within the bilayers in Chapter 5. Of particular importance, though, are interactions between carotenoids and proteins. These allow the hydrophobic carotenoids to be transported, to exist, and to function in an aqueous environment. In some cases they may modify strongly the light-absorption properties and hence the colour and photochemistry of the carotenoids.

  3. Achromatic Interaction Point Design

    SciTech Connect

    Guimei Wang,, Yaroslav Derbenev, S.Alex Bogacz, P. Chevtsov, Andre Afanaciev, Charles Ankenbrandt, Valentin Ivanov, Rolland P. Johnson

    2009-05-01

    Designers of high-luminosity energy-frontier muon colliders must provide strong beam focusing in the interaction regions. However, the construction of a strong, aberration-free beam focus is difficult and space consuming, and long straight sections generate an off-site radiation problem due to muon decay neutrinos that interact as they leave the surface of the earth. Without some way to mitigate the neutrino radiation problem, the maximum c.m. energy of a muon collider will be limited to about 3.5 TeV. A new concept for achromatic low beta design is being developed, in which the interaction region telescope and optical correction elements, are installed in the bending arcs. The concept, formulated analytically, combines space economy, a preventative approach to compensation for aberrations, and a reduction of neutrino flux concentration. An analytical theory for the aberration-free, low beta, spatially compact insertion is being developed.

  4. Multimodal Interaction Control

    NASA Astrophysics Data System (ADS)

    Beskow, Jonas; Carlson, Rolf; Edlund, Jens; Granström, Björn; Heldner, Mattias; Hjalmarsson, Anna; Skantze, Gabriel

    No matter how well hidden our systems are and how well they do their magic unnoticed in the background, there are times when direct interaction between system and human is a necessity. As long as the interaction can take place unobtrusively and without techno-clutter, this is desirable. It is hard to picture a means of interaction less obtrusive and techno-cluttered than spoken communication on human terms. Spoken face-to-face communication is the most intuitive and robust form of communication between humans imaginable. In order to exploit such human spoken communication to its full potential as an interface between human and machine, we need a much better understanding of how the more human-like aspects of spoken communication work.

  5. Solar-terrestrial interactions

    NASA Technical Reports Server (NTRS)

    1977-01-01

    The effects of solar radiation on man's environment are discussed. It is solar radiation that is the basic energy source driving the circulations of the earth's atmosphere and oceans. Solar radiation is responsible for the ionization of the earth's upper atmosphere to form the ionosphere, which is important to our understanding of the magnetosphere and its interaction with the solar wind. The solar wind, which is the continuous (but not steady) flow of the sun's coronal plasma and magnetic field into interplanetary space, plays both an active and passive role in its interaction with the earth's environment.

  6. The new interactive CESAR

    SciTech Connect

    Fox, P.B.; Yatabe, M.

    1987-01-01

    In this report the Nuclear Criticality Safety Analytical Methods Resource Center describes a new interactive version of CESAR, a critical experiments storage and retrieval program available on the Nuclear Criticality Information System (NCIS) database at Lawrence Livermore National Laboratory. The original version of CESAR did not include interactive search capabilities. The CESAR database was developed to provide a convenient, readily accessible means of storing and retrieving code input data for the SCALE Criticality Safety Analytical Sequences and the codes comprising those sequences. The database includes data for both cross section preparation and criticality safety calculations. 3 refs., 1 tab.

  7. Propeller/wing interaction

    NASA Technical Reports Server (NTRS)

    Witkowski, David P.; Johnston, Robert T.; Sullivan, John P.

    1989-01-01

    The present experimental investigation of the steady-state and unsteady-state effects due to the interaction between a tractor propeller's wake and a wing employs, in the steady case, wind tunnel measurements at low subsonic speed; results are obtained which demonstrate wing performance response to variations in configuration geometry. Other steady-state results involve the propeller-hub lift and side-force due to the wing's influence on the propeller. The unsteady effects of interaction were studied through flow visualization of propeller-tip vortex distortion over a wing, again using a tractor-propeller configuration.

  8. Propeller/wing interaction

    NASA Technical Reports Server (NTRS)

    Witkowski, David P.; Johnston, Robert T.; Sullivan, John P.

    1989-01-01

    The present experimental investigation of the steady-state and unsteady-state effects due to the interaction between a tractor propeller's wake and a wing employs, in the steady case, wind tunnel measurements at low subsonic speed; results are obtained which demonstrate wing performance response to variations in configuration geometry. Other steady-state results involve the propeller-hub lift and side-force due to the wing's influence on the propeller. The unsteady effects of interaction were studied through flow visualization of propeller-tip vortex distortion over a wing, again using a tractor-propeller configuration.

  9. Solitary water wave interactions

    NASA Astrophysics Data System (ADS)

    Craig, W.; Guyenne, P.; Hammack, J.; Henderson, D.; Sulem, C.

    2006-05-01

    This article concerns the pairwise nonlinear interaction of solitary waves in the free surface of a body of water lying over a horizontal bottom. Unlike solitary waves in many completely integrable model systems, solitary waves for the full Euler equations do not collide elastically; after interactions, there is a nonzero residual wave that trails the post-collision solitary waves. In this report on new numerical and experimental studies of such solitary wave interactions, we verify that this is the case, both in head-on collisions (the counterpropagating case) and overtaking collisions (the copropagating case), quantifying the degree to which interactions are inelastic. In the situation in which two identical solitary waves undergo a head-on collision, we compare the asymptotic predictions of Su and Mirie [J. Fluid Mech. 98, 509 (1980)] and Byatt-Smith [J. Fluid Mech. 49, 625 (1971)], the wavetank experiments of Maxworthy [J. Fluid Mech. 76, 177 (1976)], and the numerical results of Cooker, Weidman, and Bale [J. Fluid Mech. 342, 141 (1997)] with independent numerical simulations, in which we quantify the phase change, the run-up, and the form of the residual wave and its Fourier signature in both small- and large-amplitude interactions. This updates the prior numerical observations of inelastic interactions in Fenton and Rienecker [J. Fluid Mech. 118, 411 (1982)]. In the case of two nonidentical solitary waves, our precision wavetank experiments are compared with numerical simulations, again observing the run-up, phase lag, and generation of a residual from the interaction. Considering overtaking solitary wave interactions, we compare our experimental observations, numerical simulations, and the asymptotic predictions of Zou and Su [Phys. Fluids 29, 2113 (1986)], and again we quantify the inelastic residual after collisions in the simulations. Geometrically, our numerical simulations of overtaking interactions fit into the three categories of Korteweg-deVries two

  10. Interactions between interactions: predator-prey, parasite-host, and mutualistic interactions.

    PubMed

    Møller, Anders Pape

    2008-01-01

    Ecological interactions such as those between predators and prey, parasites and hosts, and pollinators and plants are usually studied on their own while neglecting that one category of interactions can have dramatic effects on another. Such interactions between interactions will have both ecological and evolutionary effects because the actions of one party will influence interactions among other parties, thereby eventually causing feedback on the first party. Examples of such interactions include the effects of predators and parasites on the evolution of host sexual selection, the effects of parasites and predators on the evolution of virulence, and the effects of parasites and predators on the evolution of pollinator mutualisms. Such interactions among interactions will generally prevent simple cases of coevolution, because any single case of interaction between two parties may be affected by an entire range of additional interacting factors. These phenomena will have implications not only for how ecologists and evolutionary biologists empirically study interactions but also on how such interactions are modeled.

  11. Teleconferencing and Interactive Media.

    ERIC Educational Resources Information Center

    Parker, Lorne A., Comp.; Olgren, Christine H., Comp.

    This publication contains more than 50 papers on the latest developments and applications of interactive media to link distant locations. The contributors, who represent business, government, education, medical, and telecommunications organizations in the United States, Canada, England, and Australia, have had direct experience with the full range…

  12. Interactive Technology for Education.

    ERIC Educational Resources Information Center

    Brooks, Robert; Perl, Barry

    1991-01-01

    By using the kind of two-way television system envisioned by Buckminster Fuller, school children can learn at their own rates and select interesting topics, thereby continually reinforcing the desire to learn. Today's new interactive video systems, from multimedia encyclopedias to hypermedia combinations, allow students to explore subject matter…

  13. Interactive Tabletops in Education

    ERIC Educational Resources Information Center

    Dillenbourg, Pierre; Evans, Michael

    2011-01-01

    Interactive tabletops are gaining increased attention from CSCL researchers. This paper analyses the relation between this technology and teaching and learning processes. At a global level, one could argue that tabletops convey a socio-constructivist flavor: they support small teams that solve problems by exploring multiple solutions. The…

  14. Interactive Genetics Tutorial Project.

    ERIC Educational Resources Information Center

    Wisconsin Univ., Madison. Dept. of Curriculum and Instruction.

    The Interactive Genetics Tutorial (IGT) project and the Intelligent Tutoring System for the IGT project named MENDEL supplement genetics instruction in biology courses by providing students with experience in designing, conducting, and evaluating genetics experiments. The MENDEL software is designed to: (1) simulate genetics experiments that…

  15. Electron interaction in matter

    NASA Technical Reports Server (NTRS)

    Dance, W. E.; Rainwater, W. J.; Rester, D. H.

    1969-01-01

    Data on the scattering of 1-MeV electrons in aluminum for the case of non-normal incidence, electron-bremsstrahlung cross-sections in thin targets, and the production of bremstrahlung by electron interaction in thick targets, are presented both in tabular and graphic form. These results may interest physicists and radiologists.

  16. Weak and electromagnetic interactions

    NASA Astrophysics Data System (ADS)

    Salam, Abdus

    One of the recurrent dreams in elementary particle physics is that of a possible fundamental synthesis between electromagnetism and weak interaction. The idea has its origin in the following shared characteristics: 1. Both forces affect equally all forms of matter -leptons as well as hadrons. 2. Both are vector in character. 3. Both (individually) possess universal coupling strengths.

  17. Interaction Information Retrieval.

    ERIC Educational Resources Information Center

    Dominich, Sandor

    1994-01-01

    Discussion of information retrieval focuses on an Interaction Information Retrieval model in which documents are interconnected; queries and documents are treated in the same way; and retrieval is the result of the interconnection between query and documents. A theoretical mathematical formulation of this type of retrieval is given. (Contains 31…

  18. GENIE final state interactions

    SciTech Connect

    Dytman, Steven

    2015-10-15

    Final state interactions are an important component of any neutrino-nucleus Monte Carlo program. GENIE has 2 FSI programs which serve different purposes. Each has fair-good agreement with a wide range of hadron-nucleus data. Recent improvements and planned advancements are described.

  19. Magnetosphere-ionosphere interactions

    NASA Technical Reports Server (NTRS)

    Vondrak, R. R.; Chiu, Y. T.; Evans, D. S.; Patterson, V. G.; Romick, G. J.; Stasiewicz, K.

    1979-01-01

    The present understanding of magnetosphere ionosphere interactions is described, and present and future predictive capabilities are assessed. Ionospheric features directly coupled to the magnetosphere to a significant degree are considered, with emphasis given to those phenomena of major interest to forecasters and users.

  20. Standardizing Interaction Design Education

    ERIC Educational Resources Information Center

    Thomassen, Aukje; Ozcan, Oguzhan

    2010-01-01

    The objective of this paper is to which extend the didactic format of studio-based group-work is applicable for creating a common-ground for Interaction Design Education in European Perspective. The current debate on design education shows us a landscape of different initiatives. So far difficulties have arisen in the area of accreditation and…

  1. Interactive Mold House Tour

    EPA Pesticide Factsheets

    Get a quick glimpse of some of the most important ways to protect your home from mold by this interactive tour of the Mold House. Room-by-room, you'll learn about common mold issues and how to address them.

  2. Data Interactive Publications Revisited

    NASA Astrophysics Data System (ADS)

    Domenico, B.; Weber, W. J.

    2011-12-01

    A few years back, the authors presented examples of online documents that allowed the reader to interact directly with datasets, but there were limitations that restricted the interaction to specific desktop analysis and display tools that were not generally available to all readers of the documents. Recent advances in web service technology and related standards are making it possible to develop systems for publishing online documents that enable readers to access, analyze, and display the data discussed in the publication from the perspective and in the manner from which the author wants it to be represented. By clicking on embedded links, the reader accesses not only the usual textual information in a publication, but also data residing on a local or remote web server as well as a set of processing tools for analyzing and displaying the data. With the option of having the analysis and display processing provided on the server, there are now a broader set of possibilities on the client side where the reader can interact with the data via a thin web client, a rich desktop application, or a mobile platform "app." The presentation will outline the architecture of data interactive publications along with illustrative examples.

  3. Data Interactive Publications

    NASA Astrophysics Data System (ADS)

    Domenico, B.; Weber, J.

    2012-04-01

    For some years now, the authors have developed examples of online documents that allowed the reader to interact directly with datasets, but there were limitations that restricted the interaction to specific desktop analysis and display tools that were not generally available to all readers of the documents. Recent advances in web service technology and related standards are making it possible to develop systems for publishing online documents that enable readers to access, analyze, and display the data discussed in the publication from the perspective and in the manner from which the author wants it to be represented. By clicking on embedded links, the reader accesses not only the usual textual information in a publication, but also data residing on a local or remote web server as well as a set of processing tools for analyzing and displaying the data. With the option of having the analysis and display processing provided on the server (or in the cloud), there are now a broader set of possibilities on the client side where the reader can interact with the data via a thin web client, a rich desktop application, or a mobile platform "app." The presentation will outline the architecture of data interactive publications along with illustrative examples.

  4. Connectionist Interaction Information Retrieval.

    ERIC Educational Resources Information Center

    Dominich, Sandor

    2003-01-01

    Discussion of connectionist views for adaptive clustering in information retrieval focuses on a connectionist clustering technique and activation spreading-based information retrieval model using the interaction information retrieval method. Presents theoretical as well as simulation results as regards computational complexity and includes…

  5. Designing Interactive Learning Systems.

    ERIC Educational Resources Information Center

    Barker, Philip

    1990-01-01

    Describes multimedia, computer-based interactive learning systems that support various forms of individualized study. Highlights include design models; user interfaces; design guidelines; media utilization paradigms, including hypermedia and learner-controlled models; metaphors and myths; authoring tools; optical media; workstations; four case…

  6. Interactive Reflective Logs

    ERIC Educational Resources Information Center

    Deaton, Cynthia Minchew; Deaton, Benjamin E.; Leland, Katina

    2010-01-01

    The authors created an interactive reflective log (IRL) to provide teachers with an opportunity to use a journal approach to record, evaluate, and communicate student understanding of science concepts. Unlike a traditional journal, the IRL incorporates prompts to encourage students to discuss their understanding of science content and science…

  7. Interactive shape metamorphosis

    NASA Technical Reports Server (NTRS)

    Chen, David T.; State, Andrei; Banks, David

    1994-01-01

    A technique for controlled metamorphosis between surfaces in 3-space is described. Well-understood techniques to produce shape metamorphosis between models in a 2D parametric space is applied. The user selects morphable features interactively, and the morphing process executes in real time on a high-performance graphics multicomputer.

  8. Electronically Enhanced Classroom Interaction.

    ERIC Educational Resources Information Center

    Draper, Stephen; Cargill, Julie; Cutts, Quintin

    A design rationale for introducing electronic equipment (a group response system) for student interaction in lecture theaters is presented, linking the instructional design to theory. The effectiveness of the equipment for learning depends mostly on what pedagogic method is employed. Various alternative types are introduced, including: assessment;…

  9. Interaction, 1996-1997.

    ERIC Educational Resources Information Center

    Hajdu-Vaughn, Susan, Ed.; Coyle, Barbara, Ed.

    1997-01-01

    This collection includes four quarterly issues of "Interaction," a publication of the Canadian Child Care Federation. Each issue addresses several topics and is arranged in four sections: opinions, practice/pratique, focus/a propos, and news/nouvelles. The opinions section includes letters and editorial/review columns, the practice…

  10. Teleconferencing and Interactive Media.

    ERIC Educational Resources Information Center

    Parker, Lorne A., Comp.; Olgren, Christine H., Comp.

    This publication contains more than 50 papers on the latest developments and applications of interactive media to link distant locations. The contributors, who represent business, government, education, medical, and telecommunications organizations in the United States, Canada, England, and Australia, have had direct experience with the full range…

  11. Adhesive interactions with wood

    Treesearch

    Charles R. Frihart

    2004-01-01

    While the chemistry for the polymerization of wood adhesives has been studied systematically and extensively, the critical aspects of the interaction of adhesives with wood are less clearly understood. General theories of bond formation need to be modified to take into account the porosity of wood and the ability of chemicals to be absorbed into the cell wall....

  12. Interactive Technology for Education.

    ERIC Educational Resources Information Center

    Brooks, Robert; Perl, Barry

    1991-01-01

    By using the kind of two-way television system envisioned by Buckminster Fuller, school children can learn at their own rates and select interesting topics, thereby continually reinforcing the desire to learn. Today's new interactive video systems, from multimedia encyclopedias to hypermedia combinations, allow students to explore subject matter…

  13. Interaction with William Carnall

    SciTech Connect

    Judd, Brian R. . E-mail: juddbr@pha.jhu.edu

    2005-02-15

    A personal account is given of interaction with William T. Carnall during the period 1977-1988, when I made regular visits to the Argonne National Laboratory to discuss the theoretical background to the spectroscopic work he was carrying out on the lanthanides and actinides.

  14. Teaching with Interactive Multimedia.

    ERIC Educational Resources Information Center

    Hudson, Tim

    Based on the idea that anyone who is interested in making entertaining and informative presentations in educational settings is interested in multimedia, this practical guide offers tips for communication (and other) teachers who want to integrate and program interactive multimedia into their courses. The guide suggests that teachers on limited…

  15. Interactive Tabletops in Education

    ERIC Educational Resources Information Center

    Dillenbourg, Pierre; Evans, Michael

    2011-01-01

    Interactive tabletops are gaining increased attention from CSCL researchers. This paper analyses the relation between this technology and teaching and learning processes. At a global level, one could argue that tabletops convey a socio-constructivist flavor: they support small teams that solve problems by exploring multiple solutions. The…

  16. Dimensions of Group Interaction

    ERIC Educational Resources Information Center

    Dawidowicz, Paula

    2008-01-01

    The correlation between positive and negative group interactions and one or another of individuals' attitudes or characteristics--moral development, critical thinking, resilience, and self efficacy--has been examined previously. However, no systemic examination of individuals' development of patterns of these characteristics and those patterns'…

  17. Electronically Enhanced Classroom Interaction.

    ERIC Educational Resources Information Center

    Draper, Stephen; Cargill, Julie; Cutts, Quintin

    A design rationale for introducing electronic equipment (a group response system) for student interaction in lecture theaters is presented, linking the instructional design to theory. The effectiveness of the equipment for learning depends mostly on what pedagogic method is employed. Various alternative types are introduced, including: assessment;…

  18. Interaction, 1996-1997.

    ERIC Educational Resources Information Center

    Hajdu-Vaughn, Susan, Ed.; Coyle, Barbara, Ed.

    1997-01-01

    This collection includes four quarterly issues of "Interaction," a publication of the Canadian Child Care Federation. Each issue addresses several topics and is arranged in four sections: opinions, practice/pratique, focus/a propos, and news/nouvelles. The opinions section includes letters and editorial/review columns, the practice…

  19. Interactive Learning by Satellite.

    ERIC Educational Resources Information Center

    Barker, Bruce O.

    1987-01-01

    Describes three systems of interactive satellite instruction for high school credit: German by Satellite, offered by the University of Oklahoma; Accelerated Learning of Spanish, originating in Utah; and the TI-IN network, which broadcasts 14 different high school courses from San Antonio, Texas. (JC)

  20. Connectionist Interaction Information Retrieval.

    ERIC Educational Resources Information Center

    Dominich, Sandor

    2003-01-01

    Discussion of connectionist views for adaptive clustering in information retrieval focuses on a connectionist clustering technique and activation spreading-based information retrieval model using the interaction information retrieval method. Presents theoretical as well as simulation results as regards computational complexity and includes…

  1. Standardizing Interaction Design Education

    ERIC Educational Resources Information Center

    Thomassen, Aukje; Ozcan, Oguzhan

    2010-01-01

    The objective of this paper is to which extend the didactic format of studio-based group-work is applicable for creating a common-ground for Interaction Design Education in European Perspective. The current debate on design education shows us a landscape of different initiatives. So far difficulties have arisen in the area of accreditation and…

  2. Nucleon-nucleon interactions

    SciTech Connect

    Wiringa, R.B.

    1996-12-31

    Nucleon-nucleon interactions are at the heart of nuclear physics, bridging the gap between QCD and the effective interactions appropriate for the shell model. We discuss the current status of {ital NN} data sets, partial-wave analyses, and some of the issues that go into the construction of potential models. Our remarks are illustrated by reference to the Argonne {ital v}{sub 18} potential, one of a number of new potentials that fit elastic nucleon-nucleon data up to 350 MeV with a {Chi}{sup 2} per datum near 1. We also discuss the related issues of three-nucleon potentials, two-nucleon charge and current operators, and relativistic effects. We give some examples of calculations that can be made using these realistic descriptions of {ital NN} interactions. We conclude with some remarks on how our empirical knowledge of {ital NN} interactions may help constrain models at the quark level, and hence models of nucleon structure.

  3. Interaction: Examples and Possibilities.

    ERIC Educational Resources Information Center

    Schick, James B. M.

    2000-01-01

    Explores examples of software that employs interactivity to engage students in a dialogue with the past: (1) "Reverse America"; (2) "Pilgrims and Indians"; (3) "Keys to Victory in the War for Independence"; (4) "Monmouth"; (5) "Critical Period"; (6) "Translating"; (7) "Founders"; and (8) "Convention". (CMK)

  4. Interacting Chaplygin gas revisited

    NASA Astrophysics Data System (ADS)

    Saha, Subhajit; Ghosh, Saumya; Gangopadhyay, Sunandan

    2017-07-01

    In this paper, the implications of considering interaction between Chaplygin gas and a barotropic fluid with constant equation of state have been explored. The unique feature of this work is that assuming an interaction Q ∝ Hρd, analytic expressions for the energy density and pressure have been derived in terms of the hypergeometric 2F1 function. It is worthwhile to mention that an interacting Chaplygin gas model was considered in 2006 by Zhang and Zhu, nevertheless, analytic solutions for the continuity equations could not be determined assuming an interaction proportional to H times the sum of the energy densities of Chaplygin gas and dust. Our model can successfully explain the transition from the early decelerating phase to the present phase of cosmic acceleration. Arbitrary choice of the free parameters of our model through trial and error shows that recent observational data strongly favors wm = 0 and wm = -1 3 over the wm = 1 3 case. Interestingly, the present model also incorporates the transition of dark energy into the phantom domain, however, future deceleration is forbidden.

  5. Interactive Reflective Logs

    ERIC Educational Resources Information Center

    Deaton, Cynthia Minchew; Deaton, Benjamin E.; Leland, Katina

    2010-01-01

    The authors created an interactive reflective log (IRL) to provide teachers with an opportunity to use a journal approach to record, evaluate, and communicate student understanding of science concepts. Unlike a traditional journal, the IRL incorporates prompts to encourage students to discuss their understanding of science content and science…

  6. Interactions of cosmic superstrings

    SciTech Connect

    Jackson, Mark G.; /Fermilab

    2007-06-01

    We develop methods by which cosmic superstring interactions can be studied in detail. These include the reconnection probability and emission of radiation such as gravitons or small string loops. Loop corrections to these are discussed, as well as relationships to (p; q)-strings. These tools should allow a phenomenological study of string models in anticipation of upcoming experiments sensitive to cosmic string radiation.

  7. Embarrassment in Dyadic Interaction.

    ERIC Educational Resources Information Center

    Edelmann, Robert J.; Hampson, Sarah E.

    1981-01-01

    Subject pairs (N=18) participated in an alternating question-and-answer session at one of two interactional distances utilizing questions which increased in their intimacy content. Results indicated topic intimacy, but not distance, affected the embarrassment potential of the situation. Increases in embarrassment caused changes in nonverbal and…

  8. INTERACT: an object oriented protein-protein interaction database.

    PubMed

    Eilbeck, K; Brass, A; Paton, N; Hodgman, C

    1999-01-01

    Protein-protein interactions provide vital information concerning the function of proteins, complexes and networks. Currently there is no widely accepted repository of this interaction information. Our aim is to provide a single database with the necessary architecture to fully store, query and analyse interaction data. An object oriented database has been created which provides scientists with a resource for examining existing protein-protein interactions and inferring possible interactions from the data stored. It also provides a basis for examining networks of interacting proteins, via analysis of the data stored. The database contains over a thousand interactions. k.eilbeck@stud.man.ac.uk

  9. The evolution of social interactions changes predictions about interacting phenotypes.

    PubMed

    Kazancıoğlu, Erem; Klug, Hope; Alonzo, Suzanne H

    2012-07-01

    In many traits involved in social interactions, such as courtship and aggression, the phenotype is an outcome of interactions between individuals. Such traits whose expression in an individual is partly determined by the phenotype of its social partner are called "interacting phenotypes." Quantitative genetic models suggested that interacting phenotypes can evolve much faster than nonsocial traits. Current models, however, consider the interaction between phenotypes of social partners as a fixed phenotypic response rule, represented by an interaction coefficient (ψ). Here, we extend existing theoretical models and incorporate the interaction coefficient as a trait that can evolve. We find that the evolution of the interaction coefficient can change qualitatively the predictions about the rate and direction of evolution of interacting phenotypes. We argue that it is crucial to determine whether and how the phenotypic response of an individual to its social partner can evolve to make accurate predictions about the evolution of traits involved in social interactions. © 2012 The Author(s).

  10. Drug Interaction and Pharmacist

    PubMed Central

    Ansari, JA

    2010-01-01

    The topic of drug–drug interactions has received a great deal of recent attention from the regulatory, scientific, and health care communities worldwide. Nonsteroidal anti-inflammatory drugs, antibiotics and, in particular, rifampin are common precipitant drugs prescribed in primary care practice. Drugs with a narrow therapeutic range or low therapeutic index are more likely to be the objects for serious drug interactions. Object drugs in common use include warfarin, fluoroquinolones, antiepileptic drugs, oral contraceptives, cisapride, and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. The pharmacist, along with the prescriber has a duty to ensure that patients are aware of the risk of side effects and a suitable course of action should they occur. With their detailed knowledge of medicine, pharmacists have the ability to relate unexpected symptoms experienced by patients to possible adverse effects of their drug therapy. PMID:21042495

  11. Interactive optical panel

    DOEpatents

    Veligdan, James T.

    1995-10-03

    An interactive optical panel assembly 34 includes an optical panel 10 having a plurality of ribbon optical waveguides 12 stacked together with opposite ends thereof defining panel first and second faces 16, 18. A light source 20 provides an image beam 22 to the panel first face 16 for being channeled through the waveguides 12 and emitted from the panel second face 18 in the form of a viewable light image 24a. A remote device 38 produces a response beam 40 over a discrete selection area 36 of the panel second face 18 for being channeled through at least one of the waveguides 12 toward the panel first face 16. A light sensor 42,50 is disposed across a plurality of the waveguides 12 for detecting the response beam 40 therein for providing interactive capability.

  12. Diabetes Interactive Atlas

    PubMed Central

    Burrows, Nilka R.; Geiss, Linda S.

    2014-01-01

    The Diabetes Interactive Atlas is a recently released Web-based collection of maps that allows users to view geographic patterns and examine trends in diabetes and its risk factors over time across the United States and within states. The atlas provides maps, tables, graphs, and motion charts that depict national, state, and county data. Large amounts of data can be viewed in various ways simultaneously. In this article, we describe the design and technical issues for developing the atlas and provide an overview of the atlas’ maps and graphs. The Diabetes Interactive Atlas improves visualization of geographic patterns, highlights observation of trends, and demonstrates the concomitant geographic and temporal growth of diabetes and obesity. PMID:24503340

  13. Volcanism-Climate Interactions

    NASA Technical Reports Server (NTRS)

    Walter, Louis S. (Editor); Desilva, Shanaka (Editor)

    1991-01-01

    The range of disciplines in the study of volcanism-climate interactions includes paleoclimate, volcanology, petrology, tectonics, cloud physics and chemistry, and climate and radiation modeling. Questions encountered in understanding the interactions include: the source and evolution of sulfur and sulfur-gaseous species in magmas; their entrainment in volcanic plumes and injection into the stratosphere; their dissipation rates; and their radiative effects. Other issues include modeling and measuring regional and global effects of such large, dense clouds. A broad-range plan of research designed to answer these questions was defined. The plan includes observations of volcanoes, rocks, trees, and ice cores, as well as satellite and aircraft observations of erupting volcanoes and resulting lumes and clouds.

  14. Evolution of intrafamilial interactions.

    PubMed Central

    Lynch, M

    1987-01-01

    A theory for the evolution of behavioral interactions among relatives is developed that allows for genetic correlations between the types of behavior that are expressed in different social contexts. Both theoretical and empirical considerations indicate that such genetic constraints will almost certainly be common in natural populations. It is shown that when genetic correlations between elements of social behavior exist, Hamilton's rule inaccurately describes the conditions for evolution by way of kin selection. The direction in which social organization evolves is a delicate function of the genetic covariance structure among behaviors expressed as an offspring, sibling, parent, etc. A change in this covariance structure caused by random genetic drift or by a change in environment for a population exhibiting genotype-environment interaction can cause the population to suddenly cross a threshold into a new selective domain. Consequently, radical changes in social organization may arise between closely related species without any major shift in selective pressures external to the population. Images PMID:3479804

  15. Interactive protein manipulation

    SciTech Connect

    SNCrivelli@lbl.gov

    2003-07-01

    We describe an interactive visualization and modeling program for the creation of protein structures ''from scratch''. The input to our program is an amino acid sequence -decoded from a gene- and a sequence of predicted secondary structure types for each amino acid-provided by external structure prediction programs. Our program can be used in the set-up phase of a protein structure prediction process; the structures created with it serve as input for a subsequent global internal energy minimization, or another method of protein structure prediction. Our program supports basic visualization methods for protein structures, interactive manipulation based on inverse kinematics, and visualization guides to aid a user in creating ''good'' initial structures.

  16. Tetrel Bonding Interactions.

    PubMed

    Bauzá, Antonio; Mooibroek, Tiddo J; Frontera, Antonio

    2016-02-01

    Tetrel (Tr) bonding is first placed into perspective as a σ-hole bonding interaction with atoms of the Tr family. An sp(3) R4Tr unit has four σ-holes with which a Lewis base can form a complex. We then highlight some inspiring crystal structures where Tr bonding is obvious, followed by an account of our own work. We have shown that Tr bonding is ubiquitous in the solid state and we have highlighted that Tr bonding with carbon is possible when C is placed in the appropriate chemical context. We hope that this account serves as an initial guide and source of inspiration for others wishing to exploit this vastly underexplored interaction.

  17. Interactive design center.

    SciTech Connect

    Pomplun, Alan R. (Sandia National Laboratories, Livermore, CA)

    2005-07-01

    Sandia's advanced computing resources provide researchers, engineers and analysts with the ability to develop and render highly detailed large-scale models and simulations. To take full advantage of these multi-million data point visualizations, display systems with comparable pixel counts are needed. The Interactive Design Center (IDC) is a second generation visualization theater designed to meet this need. The main display integrates twenty-seven projectors in a 9-wide by 3-high array with a total display resolution of more than 35 million pixels. Six individual SmartBoard displays offer interactive capabilities that include on-screen annotation and touch panel control of the facility's display systems. This report details the design, implementation and operation of this innovative facility.

  18. Interactive chemical reactivity exploration.

    PubMed

    Haag, Moritz P; Vaucher, Alain C; Bosson, Maël; Redon, Stéphane; Reiher, Markus

    2014-10-20

    Elucidating chemical reactivity in complex molecular assemblies of a few hundred atoms is, despite the remarkable progress in quantum chemistry, still a major challenge. Black-box search methods to find intermediates and transition-state structures might fail in such situations because of the high-dimensionality of the potential energy surface. Here, we propose the concept of interactive chemical reactivity exploration to effectively introduce the chemist's intuition into the search process. We employ a haptic pointer device with force feedback to allow the operator the direct manipulation of structures in three dimensions along with simultaneous perception of the quantum mechanical response upon structure modification as forces. We elaborate on the details of how such an interactive exploration should proceed and which technical difficulties need to be overcome. All reactivity-exploration concepts developed for this purpose have been implemented in the samson programming environment.

  19. Neutrinophilic nonstandard interactions

    NASA Astrophysics Data System (ADS)

    Farzan, Yasaman; Heeck, Julian

    2016-09-01

    We construct UV-complete models for nonstandard neutrino interactions mediated by a sub-GeV gauge boson Z' coupled to baryon number B or B -L . A flavor-dependent Z' coupling to neutrinos is induced by mixing a U (1 )'-charged Dirac fermion with the active neutrinos, naturally suppressing flavor violation or nonuniversality of the charged leptons to the loop level. We show that these models can give rise to large flavor-conserving as well as flavor-violating nonstandard neutral-current neutrino interactions potentially observable in current or future oscillation experiments such as DUNE without being in conflict with other constraints such as neutrino scattering or lepton-flavor-violating decays. In particular, the LMA-Dark solution to the solar-neutrino anomaly can be obtained for U (1 )B, but not for U (1 )B-L.

  20. Combustor diffuser interaction program

    NASA Technical Reports Server (NTRS)

    Srinivasan, Ram; Thorp, Daniel

    1986-01-01

    Advances in gas turbine engine performance are achieved by using compressor systems with high stage loading and low part count, which result in high exit Mach numbers. The diffuser and combustor systems in such engines should be optimized to reduce system pressure loss and to maximize the engine thrust-to-weight ratio and minimize length. The state-of-the-art combustor-diffuser systems do not meet these requirements. Detailed understanding of the combustor-diffuser flow field interaction is required for designing advanced gas turbine engines. An experimental study of the combustor-diffuser interaction (CDI) is being conducted to obtain data for the evaluation and improvement of analytical models applicable to a wide variety of diffuser designs. The CDI program consists of four technical phases: Literature Search; Baseline Configuration; Parametric Configurations; and Performance Configurations. Phase 2 of the program is in progress.

  1. Interactive optical panel

    DOEpatents

    Veligdan, J.T.

    1995-10-03

    An interactive optical panel assembly includes an optical panel having a plurality of ribbon optical waveguides stacked together with opposite ends thereof defining panel first and second faces. A light source provides an image beam to the panel first face for being channeled through the waveguides and emitted from the panel second face in the form of a viewable light image. A remote device produces a response beam over a discrete selection area of the panel second face for being channeled through at least one of the waveguides toward the panel first face. A light sensor is disposed across a plurality of the waveguides for detecting the response beam therein for providing interactive capability. 10 figs.

  2. The interactive videodisc.

    PubMed

    Leveridge, L L

    1983-04-01

    Dynamic audiovisual presentations that are interactive due to the use of videodisc systems provide more efficient and effective communication of those elements of medicine best learned by seeing them, than is possible via traditional modes. This is particularly true when externally interfaced electronic data processors are used to automate the process. While magnetic and stylus-type videodisc players can serve in education, it is the optical videodisc that has the greatest educational potential. The AMA has been exploring the capabilities of optical videodisc systems and demonstrating pilot programs that use good principles of audiovisual and computer-assisted instruction in tutorial formats or presented as patient management problems. We are on the threshold of a revolution in communication potentially as significant to education as the one which followed the invention of movable type. Using interactive videodisc programs, designed and produced with skill and care, we can solve some of medical education's most pressing problems.

  3. Interactive digital signal processor

    NASA Technical Reports Server (NTRS)

    Mish, W. H.; Wenger, R. M.; Behannon, K. W.; Byrnes, J. B.

    1982-01-01

    The Interactive Digital Signal Processor (IDSP) is examined. It consists of a set of time series analysis Operators each of which operates on an input file to produce an output file. The operators can be executed in any order that makes sense and recursively, if desired. The operators are the various algorithms used in digital time series analysis work. User written operators can be easily interfaced to the sysatem. The system can be operated both interactively and in batch mode. In IDSP a file can consist of up to n (currently n=8) simultaneous time series. IDSP currently includes over thirty standard operators that range from Fourier transform operations, design and application of digital filters, eigenvalue analysis, to operators that provide graphical output, allow batch operation, editing and display information.

  4. Titan's magnetospheric interaction

    NASA Technical Reports Server (NTRS)

    Neubauer, F. M.; Gurnett, D. A.; Scudder, J. D.; Hartle, R. E.

    1984-01-01

    Voyager 1 encounter data are used to theoretically examine the interaction of Titan with the solar wind, the Saturn magnetosheath and the Saturn magnetosphere. The spacecraft data comprised magnetometer, plasma wave, radio signal and charged particle measurements. Attention is given to the Alfven (1.9) and Mach (0.57) numbers detected in the Saturn magnetosheath, along with a fast hydrodynamic Mach number of 0.55. Incident plasma interacted with the Titan atmosphere and produced a magnetosphere through mass capture and field-line draping. The tail region was loaded with N(+) and N2(+)/H2CN(+) ions instead of the strong H(+) signals typical of other regions. The magnetotail featured four lobes, and the Titan atmosphere was calculated to lose 10 to the 24th ions/sec. Finally, the Titan internal rotationally aligned magnetic field has an estimated strength of 7 x 10 to the 20th gauss/cu cm.

  5. Antinucleon-nucleus interactions

    SciTech Connect

    Dover, C.B.

    1987-01-01

    Recent experimental and theoretical results on anti p-nucleus interactions are reviewed. We focus on determinations of the anti p optical potential from elastic scattering, the use of (anti p, anti p') inelastic scattering to reveal aspects of the spin-isospin dependence of N anti N amplitudes, and some puzzling features of (anti p, anti n) charge exchange reactions on nuclei. 47 refs., 7 figs.

  6. Mesoscale/convective interaction

    NASA Technical Reports Server (NTRS)

    Haines, P. A.; Sun, W. Y.

    1988-01-01

    A novel cumulus parameterization scheme (CPS) has been developed in order to account for mesoscale/convective-scale interaction which considers both the mesoscale and convective scale mass and moisture budgets, under the assumption that the heating rate is a maximum for given environmental conditions. The basis of the CPS is a detailed, quasi-one-dimensional cloud model that calculates mass and moisture fluxes similar to those calculated by the Schlesinger (1978) three-dimensional model.

  7. Acousto-Optic Interactions.

    DTIC Science & Technology

    The document reports the results of the experimental and theoretical investigation of acousto - optic interactions in guided wave structure for optical...waves and acoustic surface waves and experimental results of isotropic and anisotropic diffraction in LiNbO3 and quartz. A simple acousto - optic plate...CVD ZnO films on sapphire, which may be needed for the acousto - optic devices in thin films are also included. (Author)

  8. Interacting warm dark matter

    SciTech Connect

    Cruz, Norman; Palma, Guillermo; Zambrano, David; Avelino, Arturo E-mail: guillermo.palma@usach.cl E-mail: avelino@fisica.ugto.mx

    2013-05-01

    We explore a cosmological model composed by a dark matter fluid interacting with a dark energy fluid. The interaction term has the non-linear λρ{sub m}{sup α}ρ{sub e}{sup β} form, where ρ{sub m} and ρ{sub e} are the energy densities of the dark matter and dark energy, respectively. The parameters α and β are in principle not constrained to take any particular values, and were estimated from observations. We perform an analytical study of the evolution equations, finding the fixed points and their stability properties in order to characterize suitable physical regions in the phase space of the dark matter and dark energy densities. The constants (λ,α,β) as well as w{sub m} and w{sub e} of the EoS of dark matter and dark energy respectively, were estimated using the cosmological observations of the type Ia supernovae and the Hubble expansion rate H(z) data sets. We find that the best estimated values for the free parameters of the model correspond to a warm dark matter interacting with a phantom dark energy component, with a well goodness-of-fit to data. However, using the Bayesian Information Criterion (BIC) we find that this model is overcame by a warm dark matter – phantom dark energy model without interaction, as well as by the ΛCDM model. We find also a large dispersion on the best estimated values of the (λ,α,β) parameters, so even if we are not able to set strong constraints on their values, given the goodness-of-fit to data of the model, we find that a large variety of theirs values are well compatible with the observational data used.

  9. ELEMENTARY PARTICLE INTERACTIONS

    SciTech Connect

    EFREMENKO, YURI; HANDLER, THOMAS; KAMYSHKOV, YURI; SIOPSIS, GEORGE; SPANIER, STEFAN

    2013-07-30

    The High-Energy Elementary Particle Interactions group at UT during the last three years worked on the following directions and projects: Collider-based Particle Physics; Neutrino Physics, particularly participation in “NOνA”, “Double Chooz”, and “KamLAND” neutrino experiments; and Theory, including Scattering amplitudes, Quark-gluon plasma; Holographic cosmology; Holographic superconductors; Charge density waves; Striped superconductors; and Holographic FFLO states.

  10. [Brain-gut interactions].

    PubMed

    Bonaz, B

    2010-08-01

    Our digestive tract has an autonomous functioning but also has a bidirectional relation with our brain known as brain-gut interactions. This communication is mediated by the autonomous nervous system, i.e., the sympathetic and parasympathetic nervous systems, with a mixed afferent and efferent component, and the circumventricular organs located outside the blood-brain barrier. The vagus nerve, known as the principal component of the parasympathetic nervous system, is a mixed nerve composed of 90% afferent fibers, which has physiological roles due to its putative vegetative functions. The vagus nerve has also anti-inflammatory properties both through the hypothalamic pituitary adrenal axis (through its afferents) and the cholinergic anti-inflammatory pathway (through its efferents). The sympathetic nervous system has a classical antagonist effect on the parasympathetic nervous system at the origin of an equilibrated sympathovagal balance in normal conditions. The brain is able to integrate inputs coming from the digestive tract inside a central autonomic network organized around the hypothalamus, limbic system and cerebral cortex (insula, prefrontal, cingulate) and in return to modify the autonomic nervous system and the hypothalamic pituitary adrenal axis in the frame of physiological loops. A dysfunction of these brain-gut interactions, favoured by stress, is most likely involved in the pathophysiology of digestive diseases such as irritable bowel syndrome or even inflammatory bowel diseases. A better knowledge of these brain-gut interactions has therapeutic implications in the domain of pharmacology, neurophysiology, behavioural and cognitive management.

  11. Transactional interactive multimedia banner

    NASA Astrophysics Data System (ADS)

    Shae, Zon-Yin; Wang, Xiping; von Kaenel, Juerg

    2000-05-01

    Advertising in TV broadcasting has shown that multimedia is a very effective means to present merchandise and attract shoppers. This has been applied to the Web by including animated multimedia banner ads on web pages. However, the issues of coupling interactive browsing, shopping, and secure transactions e.g. from inside a multimedia banner, have only recently started to being explored. Currently there is an explosively growing amount of back-end services available (e.g., business to business commerce (B2B), business to consumer (B2C) commerce, and infomercial services) in the Internet. These services are mostly accessible through static HTML web pages at a few specific web portals. In this paper, we will investigate the feasibility of using interactive multimedia banners as pervasive access point for the B2C, B2B, and infomercial services. We present a system architecture that involves a layer of middleware agents functioning as the bridge between the interactive multimedia banners and back-end services.

  12. Biomolecular Interaction Assay

    SciTech Connect

    Bruckner-Lea, Cindy J.; Brown, L; Holman, David A.; Olson, Lydia; Grate, Jay W.

    2000-12-29

    Understanding the binding interactions of complexes of multiple proteins is an important area of medical research since many biological signaling pathways involve multiple protein complexes. A number of sensor technologies have been adapted to monitoring biomolecular interactions. Acoustic wave devices such as flexural plate wave devices, surface transverse waves, and quartz crystal microbalances detect the mass increase observed upon binding of a solution biomolecule to a surface bound biomolecule. However, these devices will also respond to changes in viscosity, temperature, liquid density, and viscoelastic effects, which may confound the interpretation of observed signals. Nonspecific binding is indistinguishable from specific binding. Several techniques for refractive index sensing, such as planar wave guides and surface plasmon resonance (SPR), can also be used to observe biomolecular interactions localized at a surface. Again, nonspecific binding is indistinguishable from specific binding. In addition, the derivatized surface must be very thin and uniform to obtain adequate sensitivity and reproducibility, and the technique is not suited for monitoring large multiple protein complexes since the measurement sensitivity decreases rapidly with distance from the sensor surface. All of these techniques use planar surfaces that are difficult to prepare and characterize, and must be prepared fresh for each assay.

  13. Bacteria-surface interactions.

    PubMed

    Tuson, Hannah H; Weibel, Douglas B

    2013-05-14

    The interaction of bacteria with surfaces has important implications in a range of areas, including bioenergy, biofouling, biofilm formation, and the infection of plants and animals. Many of the interactions of bacteria with surfaces produce changes in the expression of genes that influence cell morphology and behavior, including genes essential for motility and surface attachment. Despite the attention that these phenotypes have garnered, the bacterial systems used for sensing and responding to surfaces are still not well understood. An understanding of these mechanisms will guide the development of new classes of materials that inhibit and promote cell growth, and complement studies of the physiology of bacteria in contact with surfaces. Recent studies from a range of fields in science and engineering are poised to guide future investigations in this area. This review summarizes recent studies on bacteria-surface interactions, discusses mechanisms of surface sensing and consequences of cell attachment, provides an overview of surfaces that have been used in bacterial studies, and highlights unanswered questions in this field.

  14. Interactive reservoir simulation

    SciTech Connect

    Regtien, J.M.M. Por, G.J.A.; Stiphout, M.T. van; Vlugt, F.F. van der

    1995-12-31

    Shell`s new Modular Reservoir Simulator (MoReS) has been equipped with a comprehensive and versatile user interface called FrontEnd. Apart from providing a user-friendly environment for interactive reservoir simulation, FrontEnd serves a software platform for other dynamic simulation and reservoir-engineering applications. It offers to all supported applications a common user interface, enables the re-use of code and reduces overall maintenance and support costs associated with the embedded applications. Because of its features, FrontEnd facilitates the transfer of research results in the form of operational software to end users. When coupled with MoReS, FrontEnd can be used for pre- and post-processing and interactive simulation. The pre-processing options allow data to be inputted by means of various OSF/Motif widgets containing a spreadsheet, text editors, dialogues and graphical input. The display of the input data as well as the post-processing of all simulation results is made possible by a variety of user-defined plot of tabular (e.g. timestep summary) and array (simulation grid) data. During a simulation user-defined plots can be displayed and edited, allowing a close inspection of the results as they are being calculated. FrontEnd has been equipped with a powerful input command language, which gives the batch user as much flexibility and control over the input as the interactive user.

  15. Interactive Atlas of Histology

    PubMed Central

    Goubran, Emile Z.; Vinjamury, Sivarama P.

    2007-01-01

    Purpose: An interactive atlas of histology was developed for online use by chiropractic students to enable them to practice and self-assess their ability to identify various histological structures. This article discusses the steps in the development, implementation, and usefulness of an interactive atlas of histology for students who take histology examinations. Methods: The atlas was developed by digitizing images imported through a video-microscope using actual microscope slides. Leica EWS 2100 and PowerPoint software were used to construct the atlas. The usefulness of the atlas was assessed through a comparison of histology exam scores between four classes before and four classes after the use of the atlas. Analysis of admissions data, including overall grade point average (GPA), science and nonscience GPA, and a number of course units, was done initially to avoid any identifiable differences in the academic competency between the two being compared. A survey of the students was also done to assess atlas usefulness and students' satisfaction with the atlas. Results: Analysis of histology exam scores showed that the average scores in the lab exam were significantly higher for the classes that used the atlas. Survey results showed a high level of student satisfaction with the atlas. Conclusion: The development and use of an online interactive atlas of histology for chiropractic students helped to improve lab exams scores. In addition, students were satisfied with the features and usefulness of this atlas. PMID:18483638

  16. Bacteria-surface interactions

    PubMed Central

    Tuson, Hannah H.; Weibel, Douglas B.

    2013-01-01

    The interaction of bacteria with surfaces has important implications in a range of areas, including bioenergy, biofouling, biofilm formation, and the infection of plants and animals. Many of the interactions of bacteria with surfaces produce changes in the expression of genes that influence cell morphology and behavior, including genes essential for motility and surface attachment. Despite the attention that these phenotypes have garnered, the bacterial systems used for sensing and responding to surfaces are still not well understood. An understanding of these mechanisms will guide the development of new classes of materials that inhibit and promote cell growth, and complement studies of the physiology of bacteria in contact with surfaces. Recent studies from a range of fields in science and engineering are poised to guide future investigations in this area. This review summarizes recent studies on bacteria-surface interactions, discusses mechanisms of surface sensing and consequences of cell attachment, provides an overview of surfaces that have been used in bacterial studies, and highlights unanswered questions in this field. PMID:23930134

  17. Pharmacological interactions of vasoconstrictors.

    PubMed

    Gómez-Moreno, Gerardo; Guardia, Javier; Cutando, Antonio; Calvo-Guirado, José Luis

    2009-01-01

    This article is the first of a series on pharmacological interactions involving medicaments commonly prescribed and/or used in odontology: vasoconstrictors in local anaesthetics and anti-inflammatory and anti-microbial analgesics. The necessity for the odontologist to be aware of adverse reactions as a result of the pharmacological interactions is due to the increase in medicament consumption by the general population. There is a demographic change with greater life expectancy and patients have increased chronic health problems and therefore have increased medicament intake. The presence of adrenaline (epinephrine) and other vasoconstrictors in local odontological anaesthetics is beneficial in relation to the duration and depth of anaesthesia and reduces bleeding and systemic toxicity of the local anaesthetic. However, it might produce pharmacological interactions between the injected vasoconstrictors and the local anaesthetic and adrenergic medicament administered exogenically which the odontologist should be aware of, especially because of the risk of consequent adverse reactions. Therefore the importance of conducting a detailed clinical history of the general state of health and include all medicaments, legal as well as illegal, taken by the patient.

  18. Weakly nonlinear magnetohydrodynamic wave interactions

    SciTech Connect

    Webb, G.M.; Brio, M.; Kruse, M.T.; Zank, G.P.

    1999-06-01

    Equations describing weakly nonlinear magnetohydrodynamic (MHD) wave interactions in one Cartesian space dimension are discussed. For wave propagation in uniform media, the wave interactions of interest consist of: (a) three-wave resonant interactions in which high frequency waves, may evolve on long space and time scales if the wave phases satisfy the resonance conditions; (b) Burgers self-wave steepening for the magnetoacoustic waves, and (c) mean wave field effects, in which a particular wave interacts with the mean wave field of the other waves. For wave propagation in non-uniform media, further linear wave mixing terms appear in the equations. The equations describe four types of resonant triads: slow-fast magnetosonic wave interaction; Alfv{acute e}n-entropy wave interaction; Alfv{acute e}n-magnetosonic wave interaction; and magnetosonic-entropy wave interaction. The formalism is restricted to coherent wave interactions. {copyright} {ital 1999 American Institute of Physics.}

  19. Interactive Learning and "Clickers"

    NASA Astrophysics Data System (ADS)

    Rudolph, Alexander

    2006-12-01

    A growing body of evidence demonstrates that student understanding and retention of key concepts in science can be dramatically improved by using “Interactive Learning” techniques. Interactive learning is a way to get students more actively involved in their own learning than by simple lecture alone. I will focus on one type of interactive learning activity, known as “Think-Pair-Share”. After a brief (10-20 minute) lecture on a topic, students are asked a conceptually challenging multiple-choice question. After they answer, if there is sufficient disagreement, the students discuss the question in small groups after which they answer the same question again. Frequently, the percentage of correct answers goes up, indicating that the active role of speaking and listening, together with peer instruction, has helped students better grasp the concept being tested. If disagreement persists, or if students continue to have questions, a short, class-wide discussion can be held. Clickers provide an excellent means to collect students’ answers to “Think-Pair-Share” questions in real time. Although clickers are not essential, they do provide some advantages over alternatives such as flash cards: answers are completely anonymous (though you as instructor can record individual responses); you can display a histogram of results immediately, either before or after group discussion, providing immediate feedback; by recording the results, you can give students credit for their participation in class. In this talk, I will model “Think-Pair-Share” with the audience using clickers, show results from my classes before and after group discussions, share results of a student survey on “Think-Pair-Share” and clickers, describe other uses of clickers (e.g., taking attendance, surveys, test administration) and highlight some of the pros and cons of clickers v. flashcards.

  20. Intelligently interactive combat simulation

    NASA Astrophysics Data System (ADS)

    Fogel, Lawrence J.; Porto, Vincent W.; Alexander, Steven M.

    2001-09-01

    To be fully effective, combat simulation must include an intelligently interactive enemy... one that can be calibrated. But human operated combat simulations are uncalibratable, for we learn during the engagement, there's no average enemy, and we cannot replicate their culture/personality. Rule-based combat simulations (expert systems) are not interactive. They do not take advantage of unexpected mistakes, learn, innovate, and reflect the changing mission/situation. And it is presumed that the enemy does not have a copy of the rules, that the available experts are good enough, that they know why they did what they did, that their combat experience provides a sufficient sample and that we know how to combine the rules offered by differing experts. Indeed, expert systems become increasingly complex, costly to develop, and brittle. They have face validity but may be misleading. In contrast, intelligently interactive combat simulation is purpose- driven. Each player is given a well-defined mission, reference to the available weapons/platforms, their dynamics, and the sensed environment. Optimal tactics are discovered online and in real-time by simulating phenotypic evolution in fast time. The initial behaviors are generated randomly or include hints. The process then learns without instruction. The Valuated State Space Approach provides a convenient way to represent any purpose/mission. Evolutionary programming searches the domain of possible tactics in a highly efficient manner. Coupled together, these provide a basis for cruise missile mission planning, and for driving tank warfare simulation. This approach is now being explored to benefit Air Force simulations by a shell that can enhance the original simulation.

  1. Interactive Classification Technology

    NASA Technical Reports Server (NTRS)

    deBessonet, Cary

    2000-01-01

    The investigators upgraded a knowledge representation language called SL (Symbolic Language) and an automated reasoning system called SMS (Symbolic Manipulation System) to enable the more effective use of the technologies in automated reasoning and interactive classification systems. The overall goals of the project were: 1) the enhancement of the representation language SL to accommodate a wider range of meaning; 2) the development of a default inference scheme to operate over SL notation as it is encoded; and 3) the development of an interpreter for SL that would handle representations of some basic cognitive acts and perspectives.

  2. Flank solar wind interaction

    NASA Technical Reports Server (NTRS)

    Moses, Stewart L.; Greenstadt, Eugene W.

    1992-01-01

    This report summarizes the results of the first 12 months of our program to study the interaction of the Earth's magnetosphere with the solar wind on the far flanks of the bow shock. This study employs data from the ISEE-3 spacecraft during its traversals of the Earth's magnetotail and correlative data from spacecraft monitoring the solar wind upstream. Our main effort to date has involved assembling data sets and developing new plotting programs. Two talks were given at the Spring Meeting of the American Geophysical Union describing our initial results from analyzing data from the far flank foreshock and magnetosheath. The following sections summarize our results.

  3. Human Computer Interaction

    NASA Astrophysics Data System (ADS)

    Bhagwani, Akhilesh; Sengar, Chitransh; Talwaniper, Jyotsna; Sharma, Shaan

    2012-08-01

    The paper basically deals with the study of HCI (Human computer interaction) or BCI(Brain-Computer-Interfaces) Technology that can be used for capturing brain signals and translating them into commands that allow humans to control (just by thinking) devices such as computers, robots, rehabilitation technology and virtual reality environments. The HCI is based as a direct communication pathway between the brain and an external device. BCIs are often aimed at assisting, augmenting, or repairing human cognitive or sensory-motor functions.The paper also deals with many advantages of BCI Technology along with some of its applications and some major drawbacks.

  4. Integrin Cytoplasmic Tail Interactions

    PubMed Central

    2015-01-01

    Integrins are heterodimeric cell surface adhesion receptors essential for multicellular life. They connect cells to the extracellular environment and transduce chemical and mechanical signals to and from the cell. Intracellular proteins that bind the integrin cytoplasmic tail regulate integrin engagement of extracellular ligands as well as integrin localization and trafficking. Cytoplasmic integrin-binding proteins also function downstream of integrins, mediating links to the cytoskeleton and to signaling cascades that impact cell motility, growth, and survival. Here, we review key integrin-interacting proteins and their roles in regulating integrin activity, localization, and signaling. PMID:24467163

  5. Intersensory Interactions in Hermissenda

    PubMed Central

    Alkon, Daniel L.

    1973-01-01

    Hair cells of the Hermissenda statocyst respond to photic stimulation. This response requires the presence of at least one of the two eyes. Two principal hair cell responses to light were observed. The activity of photoreceptors in response to a light step is interrupted during firing of contralateral hair cells. The intersensory interactions between the statocyst and visual pathway underlying these responses were examined with simultaneous intracellular recordings. Evidence is presented that the statocyst of Hermissenda is an important channel for visual information. PMID:4352950

  6. Plasma Interactions with Spacecraft

    DTIC Science & Technology

    2007-03-16

    Ultraviolet Limb Imager on DMSP, IEEE Trans Plasma Science, 34, No. 5, p 2062, 2006. V.A. Davis , M.J. Mandell, D.L. Cooke, D.C. Ferguson , Nascap...AFRL-VS-HA-TR-2007-1062 Plasma Interactions with Spacecraft V.A. Davis M.J. Mandell S.L. Huston R.A. Kuharski B.M. Gardner...using MSM output generated using three different MSM input parameter sets. The results were included in the presentation prepared by Dr. Hilmer of

  7. Visuo-Vestibular Interactions

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Session TA3 includes short reports covering: (1) Vestibulo-Oculomotor Interaction in Long-Term Microgravity; (2) Effects of Weightlessness on the Spatial Orientation of Visually Induced Eye Movements; (3) Adaptive Modification of the Three-Dimensional Vestibulo-Ocular Reflex during Prolonged Microgravity; (4) The Dynamic Change of Brain Potential Related to Selective Attention to Visual Signals from Left and Right Visual Fields; (5) Locomotor Errors Caused by Vestibular Suppression; and (6) A Novel, Image-Based Technique for Three-Dimensional Eye Measurement.

  8. [Hormonal contraception interactions].

    PubMed

    Hurt, K; Sottner, J; Záhumenský, J; Halaska, M; Krcmár, M; Krajcová, A

    2006-12-01

    The purpose of this article is to discuss the probable ways of interactions between some drugs or remedies and steroid contraceptives. A review article. OBGYN Clinic of the 1t Faculty of Medicine, Prague, Teaching Hospital Bulovka. Low dose oral contraceptives are very popular these days. Some drugs and remedies could negatively influence the levels of ethinyl estradiol (EE) and/or progestins and thus increase the possibility of their failure. These drugs mostly implicate as an inducer of the CYP450 system (liver) and as an inducer of P-glycoprotein transport system (transmembrane drug pump in the intestines). We wanted to describe briefly the mechanism and the principles of their impact.

  9. DUST-PLASMA INTERACTIONS

    SciTech Connect

    Dr. M. Rosenberg

    2010-01-05

    The objective of our theoretical research under this grant over the past 3 years was to develop new understanding in a range of topics in the physics of dust-plasma interactions, with application to space and the laboratory. We conducted studies related to the physical properties of dust, waves and instabilities in both weakly coupled and strongly coupled dusty plasmas, and innovative possible applications. A major consideration in our choice of topics was to compare theory with experiments or observations, and to motivate new experiments, which we believe is important for developing this relatively new field. Our research is summarized, with reference to our list of journal publications.

  10. Twisting Plasma Interactions

    NASA Image and Video Library

    2017-06-19

    Several short stalks of cooler, darker plasma spun and twisted as they interacted with each other at the sun's edge (June 14-15, 2017). The row of strands, which together form a prominence, were being pulled back and forth by magnetic forces. The dynamic action was observed for just over one day. Also noteworthy is the rapid development of a bright active region in the upper right about halfway through the clip. Movies are available at https://photojournal.jpl.nasa.gov/catalog/PIA21761

  11. Dust-magnetospheric interactions

    NASA Technical Reports Server (NTRS)

    Mendis, D. A.

    1979-01-01

    The important processes controlling the electrical potentials of dust grains in planetary magnetospheres are considered, and the quasi-equilibrium electric potentials acquired by them in the different plasma and radiative environments encountered are evaluated. The orbital dynamics of such charged grains is discussed, and their interaction with satellites within the planetary magnetospheres is considered. The possibility of magneto-gravitational capture of these gains by magnetospheres, to form dust rings around the planets, is also discussed. Finally, the possible break-up of grains charged to large electrical potentials and its consequences are briefly addressed.

  12. Bunyavirus-Vector Interactions

    PubMed Central

    Horne, Kate McElroy; Vanlandingham, Dana L.

    2014-01-01

    The Bunyaviridae family is comprised of more than 350 viruses, of which many within the Hantavirus, Orthobunyavirus, Nairovirus, Tospovirus, and Phlebovirus genera are significant human or agricultural pathogens. The viruses within the Orthobunyavirus, Nairovirus, and Phlebovirus genera are transmitted by hematophagous arthropods, such as mosquitoes, midges, flies, and ticks, and their associated arthropods not only serve as vectors but also as virus reservoirs in many cases. This review presents an overview of several important emerging or re-emerging bunyaviruses and describes what is known about bunyavirus-vector interactions based on epidemiological, ultrastructural, and genetic studies of members of this virus family. PMID:25402172

  13. Detection of molecular interactions

    DOEpatents

    Groves, John T [Berkeley, CA; Baksh, Michael M [Fremont, CA; Jaros, Michal [Brno, CH

    2012-02-14

    A method and assay are described for measuring the interaction between a ligand and an analyte. The assay can include a suspension of colloidal particles that are associated with a ligand of interest. The colloidal particles are maintained in the suspension at or near a phase transition state from a condensed phase to a dispersed phase. An analyte to be tested is then added to the suspension. If the analyte binds to the ligand, a phase change occurs to indicate that the binding was successful.

  14. Imitation, Interaction and Dialogue Using Intensive Interaction: Tea Party Rules

    ERIC Educational Resources Information Center

    Barber, Mark

    2007-01-01

    Intensive Interaction has become widely used when building up communication with children with profound learning difficulties. Often practitioners understand Intensive Interaction to be primarily about imitation and Mark Barber shows how this can be a "mis"understanding that limits the kinds of interactions that can be enjoyed by conversation…

  15. Cotton and Protein Interactions

    SciTech Connect

    Goheen, Steven C.; Edwards, J. V.; Rayburn, Alfred R.; Gaither, Kari A.; Castro, Nathan J.

    2006-06-30

    The adsorbent properties of important wound fluid proteins and cotton cellulose are reviewed. This review focuses on the adsorption of albumin to cotton-based wound dressings and some chemically modified derivatives targeted for chronic wounds. Adsorption of elastase in the presence of albumin was examined as a model to understand the interactive properties of these wound fluid components with cotton fibers. In the chronic non-healing wound, elastase appears to be over-expressed, and it digests tissue and growth factors, interfering with the normal healing process. Albumin is the most prevalent protein in wound fluid, and in highly to moderately exudative wounds, it may bind significantly to the fibers of wound dressings. Thus, the relative binding properties of both elastase and albumin to wound dressing fibers are of interest in the design of more effective wound dressings. The present work examines the binding of albumin to two different derivatives of cotton, and quantifies the elastase binding to the same derivatives following exposure of albumin to the fiber surface. An HPLC adsorption technique was employed coupled with a colorimetric enzyme assay to quantify the relative binding properties of albumin and elastase to cotton. The results of wound protein binding are discussed in relation to the porosity and surface chemistry interactions of cotton and wound proteins. Studies are directed to understanding the implications of protein adsorption phenomena in terms of fiber-protein models that have implications for rationally designing dressings for chronic wounds.

  16. Charged Dust Aggregate Interactions

    NASA Astrophysics Data System (ADS)

    Matthews, Lorin; Hyde, Truell

    2015-11-01

    A proper understanding of the behavior of dust particle aggregates immersed in a complex plasma first requires a knowledge of the basic properties of the system. Among the most important of these are the net electrostatic charge and higher multipole moments on the dust aggregate as well as the manner in which the aggregate interacts with the local electrostatic fields. The formation of elongated, fractal-like aggregates levitating in the sheath electric field of a weakly ionized RF generated plasma discharge has recently been observed experimentally. The resulting data has shown that as aggregates approach one another, they can both accelerate and rotate. At equilibrium, aggregates are observed to levitate with regular spacing, rotating about their long axis aligned parallel to the sheath electric field. Since gas drag tends to slow any such rotation, energy must be constantly fed into the system in order to sustain it. A numerical model designed to analyze this motion provides both the electrostatic charge and higher multipole moments of the aggregate while including the forces due to thermophoresis, neutral gas drag, and the ion wakefield. This model will be used to investigate the ambient conditions leading to the observed interactions. This research is funded by NSF Grant 1414523.

  17. Relationality and social interaction.

    PubMed

    Bottero, Wendy

    2009-06-01

    This paper explores Bourdieu's account of a relational social space, and his relative neglect of social interaction within this framework. Bourdieu includes social capital as one of the key relational elements of his social space, but says much less about it than economic or cultural capital, and levels of social capital are rarely measured in his work. Bourdieu is reluctant to focus on the content of social networks as part of his rejection of substantialist thinking. The neglect of substantive networks creates problems for Bourdieu's framework, because many of Bourdieu's core concepts rest upon assumptions about their interactional properties (in particular, the prevalence of homophilous differential association) which are left unexamined. It is argued here that Bourdieu's neglect of the substance of social networks is related to the criticisms that Bourdieu's framework often encounters, and that this neglect bears re-examination, since it is helpful to think of the ways in which differentiated social networks contribute to the development of habitus, help form fields, and so constitute the intersubjective social relations within which sociality, and practice more generally, occur.

  18. Strong-interaction nonuniversality

    SciTech Connect

    Volkas, R. R.; Foot, R.; He, X.; Joshi, G. C.

    1989-07-01

    The universal QCD color theory is extended to an SU(3)/sub 1//direct product/SU(3)/sub 2//direct product/SU(3)/sub 3/ gauge theory, where quarks of the /ital i/th generation transform as triplets under SU(3)/sub /ital i// and singlets under the other two factors. The usual color group is then identified with the diagonal subgroup, which remains exact after symmetry breaking. The gauge bosons associated with the 16 broken generators then form two massive octets under ordinary color. The interactions between quarks and these heavy gluonlike particles are explicitly nonuniversal and thus an exploration of their physical implications allows us to shed light on the fundamental issue of strong-interaction universality. Nonuniversality and weak flavor mixing are shown to generate heavy-gluon-induced flavor-changing neutral currents. The phenomenology of these processes is studied, as they provide the major experimental constraint on the extended theory. Three symmetry-breaking scenarios are presented. The first has color breaking occurring at the weak scale, while the second and third divorce the two scales. The third model has the interesting feature of radiatively induced off-diagonal Kobayashi-Maskawa matrix elements.

  19. Interactive Terascale Particle Visualization

    NASA Technical Reports Server (NTRS)

    Ellsworth, David; Green, Bryan; Moran, Patrick

    2004-01-01

    This paper describes the methods used to produce an interactive visualization of a 2 TB computational fluid dynamics (CFD) data set using particle tracing (streaklines). We use the method introduced by Bruckschen et al. [2001] that pre-computes a large number of particles, stores them on disk using a space-filling curve ordering that minimizes seeks, and then retrieves and displays the particles according to the user's command. We describe how the particle computation can be performed using a PC cluster, how the algorithm can be adapted to work with a multi-block curvilinear mesh, and how the out-of-core visualization can be scaled to 296 billion particles while still achieving interactive performance on PG hardware. Compared to the earlier work, our data set size and total number of particles are an order of magnitude larger. We also describe a new compression technique that allows the lossless compression of the particles by 41% and speeds the particle retrieval by about 30%.

  20. Cephradine antacids interaction studies.

    PubMed

    Arayne, M Saeed; Sultana, Najma; Afzal, M

    2007-07-01

    The present work comprises of interaction studies of cephradine with antacids. Cephradine is included among the first generation cephalosporin, which is active against a wide range of Gram positive and Gram-negative bacteria including penicillinase-producing staphylococci. Since the presence of complexing ligand may affect the bioavailability of a drug in blood or tissues, therefore, in order to study the probable interaction of cephradine with antacids all the reaction conditions were simulated to natural environments. Antacids are commonly used in patients complaining of GI irritations. The behavior of cephradine in presence of seven antacids i.e., simethicone, magaldrate, magnesium carbonate, magnesium hydroxide, magnesium trisilicate, sodium bicarbonate and aluminium hydroxide was studied by using standard dissolution apparatus. Cephradine was monitored both by UV and by high performance liquid chromatography. The results revealed that antacids containing polyvalent cations retarded the in vitro availability of cephradine. Moreover, these studies indicated that cephradine was strongly adsorbed on antacids; magnesium trisilicate and simeco tablets (powdered) exhibited relatively higher adsorption capacities.

  1. Neutron Star - Magnetosphere Interactions

    NASA Astrophysics Data System (ADS)

    Ponce, Marcelo; Anderson, Matthew; Lehner, Luis; Liebling, Steven L.; Palenzuela, Carlos

    2012-03-01

    In this work we report results of the interaction of a neutron star magnetosphere in both collapsing and moving scenarios interacting with an ambient magnetic field. In recent works [1,2], it has been shown the important role and realism associated with studies of electromagnetic environments in some particular regimes, such as: ideal-MHD, force-free, and electro-vacuum. Motivated by this and their astrophysical implications for BBH and hybrid BH-NS mergers [3,4], we study the following cases: collapse of a magnetized NS, head-on collision of a BH-NS, and orbiting merger of a BH-NS. Based in the results from our simulations, we draw some relevant conclusions to the production of jets as described within the force-free formalism. [4pt] [1] C.Palenzuela, L.Lehner and S.Liebling, Science 329, 927 (2010).[0pt] [2] C.Palenzuela, T.Garrett, et al., Phys.Rev.D 82, 044045 (2010).[0pt] [3] L.Lehner, C.Palenzuela, et al., 2011.[0pt] [4] S.Liebling, L.Lehner, et al., Phys.Rev.D 81, 124023 (2010).

  2. Time reversal interactive objects

    NASA Astrophysics Data System (ADS)

    Ing, Ros Ki; Quieffin, Nicolas; Catheline, Stefan; Fink, Mathias

    2001-05-01

    Time reversal has shown to be a fruitful concept in nondestructive testing in underwater acoustic or in ultrasonic imaging. In this paper this technique is adapted in the audible range to transform every day objects into tactile sensitive interfaces. A quick historical background is presented in the ultrasonic field and specially in chaotic cavity. In all time reversal experiments, it is demonstrated that a wave field spatially and temporally recorded is able to back propagate to its source. In other words, the field contains all the information on the location of the source. In the interactive experiments, it is shown that touching an object like a window, a table or a world globe generates an acoustic field easily detectable with one or two acoustic sensors. Using the concept of time reversal, the source location is deduced in real time. Then, touching objects at specific locations (virtual switches) is used to activate devices. Such devices are for example lights, stereo volume, or computer software. From a technical point of view, all these interactive experiments just use some computation easily performed with a standard personnel computer.

  3. Interactive Computer Graphics

    NASA Technical Reports Server (NTRS)

    Kenwright, David

    2000-01-01

    Aerospace data analysis tools that significantly reduce the time and effort needed to analyze large-scale computational fluid dynamics simulations have emerged this year. The current approach for most postprocessing and visualization work is to explore the 3D flow simulations with one of a dozen or so interactive tools. While effective for analyzing small data sets, this approach becomes extremely time consuming when working with data sets larger than one gigabyte. An active area of research this year has been the development of data mining tools that automatically search through gigabyte data sets and extract the salient features with little or no human intervention. With these so-called feature extraction tools, engineers are spared the tedious task of manually exploring huge amounts of data to find the important flow phenomena. The software tools identify features such as vortex cores, shocks, separation and attachment lines, recirculation bubbles, and boundary layers. Some of these features can be extracted in a few seconds; others take minutes to hours on extremely large data sets. The analysis can be performed off-line in a batch process, either during or following the supercomputer simulations. These computations have to be performed only once, because the feature extraction programs search the entire data set and find every occurrence of the phenomena being sought. Because the important questions about the data are being answered automatically, interactivity is less critical than it is with traditional approaches.

  4. Herb-drug interactions.

    PubMed

    Fugh-Berman, A

    2000-01-08

    Concurrent use of herbs may mimic, magnify, or oppose the effect of drugs. Plausible cases of herb-drug interactions include: bleeding when warfarin is combined with ginkgo (Ginkgo biloba), garlic (Allium sativum), dong quai (Angelica sinensis), or danshen (Salvia miltiorrhiza); mild serotonin syndrome in patients who mix St John's wort (Hypericum perforatum) with serotonin-reuptake inhibitors; decreased bioavailability of digoxin, theophylline, cyclosporin, and phenprocoumon when these drugs are combined with St John's wort; induction of mania in depressed patients who mix antidepressants and Panax ginseng; exacerbation of extrapyramidal effects with neuroleptic drugs and betel nut (Areca catechu); increased risk of hypertension when tricyclic antidepressants are combined with yohimbine (Pausinystalia yohimbe); potentiation of oral and topical corticosteroids by liquorice (Glycyrrhiza glabra); decreased blood concentrations of prednisolone when taken with the Chinese herbal product xaio chai hu tang (sho-salko-to); and decreased concentrations of phenytoin when combined with the Ayurvedic syrup shankhapushpi. Anthranoid-containing plants (including senna [Cassia senna] and cascara [Rhamnus purshiana]) and soluble fibres (including guar gum and psyllium) can decrease the absorption of drugs. Many reports of herb-drug interactions are sketchy and lack laboratory analysis of suspect preparations. Health-care practitioners should caution patients against mixing herbs and pharmaceutical drugs.

  5. XEphem: Interactive Astronomical Ephemeris

    NASA Astrophysics Data System (ADS)

    Downey, Elwood Charles

    2011-12-01

    XEphem is a scientific-grade interactive astronomical ephemeris package for UNIX-like systems. Written in C, X11 and Motif, it is easily ported to systems. Among other things, XEphem: computes heliocentric, geocentric and topocentric information for all objects; has built-in support for all planets; the moons of Mars, Jupiter, Saturn, Uranus and Earth; central meridian longitude of Mars and Jupiter; Saturn's rings; and Jupiter's Great Red Spot; allows user-defined objects including stars, deepsky objects, asteroids, comets and Earth satellites; provides special efficient handling of large catalogs including Tycho, Hipparcos, GSC; displays data in configurable tabular formats in conjunction with several interactive graphical views; displays a night-at-a-glance 24 hour graphic showing when any selected objects are up; displays 3-D stereo Solar System views that are particularly well suited for visualizing comet trajectories; quickly finds all close pairs of objects in the sky; and sorts and prints all catalogs with very flexible criteria for creating custom observing lists. Its capabilities are listed more fully in the user manual introduction.

  6. Metal-dielectric interactions

    NASA Technical Reports Server (NTRS)

    Buckley, D. H.

    1979-01-01

    Metal direlectric surface interactions and dielectric films on metal substrates were investigated. Since interfacial interaction depends so heavily on the nature of the surfaces, analytical surface tools such as Auger emission spectroscopy, X-ray photoelectron spectroscopy and field ion microscopy were used to assist in surface and interfacial characterization. The results indicate that with metals contacting certain glasses in the clean state interfacial, bonding produces fractures in the glasses while when a film such as water is present, fractures occur in the metal near the interface. Friction forces were used to measure the interfacial bond strengths. Studies with metals contacting polymers using field ion microscopy revealed that strong bonding forces could develop being between a metal and polymer surface with polymer transferring to the metal surface in various ways depending upon the forces applied to the surface in contact. With the deposition of refractory carbides, silicides and borides onto metal and alloy substrates the presence of oxides at the interface or active gases in the deposition plasma were shown to alter interfacial properties and chemistry. Auger ion depth profile analysis indicated the chemical composition at the interface and this could be related to the mechanical, friction, and wear behavior of the coating.

  7. Dynamics of Interacting Diseases

    NASA Astrophysics Data System (ADS)

    Sanz, Joaquín; Xia, Cheng-Yi; Meloni, Sandro; Moreno, Yamir

    2014-10-01

    Current modeling of infectious diseases allows for the study of complex and realistic scenarios that go from the population to the individual level of description. However, most epidemic models assume that the spreading process takes place on a single level (be it a single population, a metapopulation system, or a network of contacts). In particular, interdependent contagion phenomena can be addressed only if we go beyond the scheme-one pathogen-one network. In this paper, we propose a framework that allows us to describe the spreading dynamics of two concurrent diseases. Specifically, we characterize analytically the epidemic thresholds of the two diseases for different scenarios and compute the temporal evolution characterizing the unfolding dynamics. Results show that there are regions of the parameter space in which the onset of a disease's outbreak is conditioned to the prevalence levels of the other disease. Moreover, we show, for the susceptible-infected-susceptible scheme, that under certain circumstances, finite and not vanishing epidemic thresholds are found even at the limit for scale-free networks. For the susceptible-infected-removed scenario, the phenomenology is richer and additional interdependencies show up. We also find that the secondary thresholds for the susceptible-infected-susceptible and susceptible-infected-removed models are different, which results directly from the interaction between both diseases. Our work thus solves an important problem and paves the way toward a more comprehensive description of the dynamics of interacting diseases.

  8. New particles and interactions

    SciTech Connect

    Gilman, F.J.; Grannis, P.D.

    1984-04-01

    The Working Group on New Particles and Interactions met as a whole at the beginning and at the end of the Workshop. However, much of what was accomplished was done in five subgroups. These were devoted to: (1) new quarks and leptons; (2) technicolor; (3) supersymmetry; (4) rare decays and CP; and (5) substructure of quarks and leptons. Other aspects of new particles, e.g., Higgs, W', Z', fell to the Electroweak Working Group to consider. The central question of this Workshop of comparing anti pp (with L = 10/sup 32//cm/sup 2/-sec) with pp (with L = 10/sup 33//cm/sup 2/-sec) colliders carried through to all these subgroups. In addition there were several other aspects of hadron colliders which were considered: what does an increase in ..sqrt..s gain in cross section and resultant sensitivity to new physics versus an increase in luminosity; will polarized beams or the use of asymmetries be essential in finding new interactions; where and at what level do rate limitations due to triggering or detection systems play a role; and how and where will the detection of particles with short, but detectable, lifetimes be important. 25 references.

  9. JSPAM: Interacting galaxies modeller

    NASA Astrophysics Data System (ADS)

    Wallin, John F.; Holincheck, Anthony; Harvey, Allen

    2015-11-01

    JSPAM models galaxy collisions using a restricted n-body approach to speed up computation. Instead of using a softened point-mass potential, the software supports a modified version of the three component potential created by Hernquist (1994, ApJS 86, 389). Although spherically symmetric gravitationally potentials and a Gaussian model for the bulge are used to increase computational efficiency, the potential mimics that of a fully consistent n-body model of a galaxy. Dynamical friction has been implemented in the code to improve the accuracy of close approaches between galaxies. Simulations using this code using thousands of particles over the typical interaction times of a galaxy interaction take a few seconds on modern desktop workstations, making it ideal for rapidly prototyping the dynamics of colliding galaxies. Extensive testing of the code has shown that it produces nearly identical tidal features to those from hierarchical tree codes such as Gadget but using a fraction of the computational resources. This code was used in the Galaxy Zoo: Mergers project and is very well suited for automated fitting of galaxy mergers with automated pattern fitting approaches such as genetic algorithms. Java and Fortran versions of the code are available.

  10. Incremental full configuration interaction

    NASA Astrophysics Data System (ADS)

    Zimmerman, Paul M.

    2017-03-01

    The incremental expansion provides a polynomial scaling method for computing electronic correlation energies. This article details a new algorithm and implementation for the incremental expansion of full configuration interaction (FCI), called iFCI. By dividing the problem into n-body interaction terms, accurate correlation energies can be recovered at low n in a highly parallel computation. Additionally, relatively low-cost approximations are possible in iFCI by solving for each incremental energy to within a specified threshold. Herein, systematic tests show that FCI-quality energies can be asymptotically reached for cases where dynamic correlation is dominant as well as where static correlation is vital. To further reduce computational costs and allow iFCI to reach larger systems, a select-CI approach (heat-bath CI) requiring two parameters is incorporated. Finally, iFCI provides the first estimate of FCI energies for hexatriene with a polarized double zeta basis set, which has 32 electrons correlated in 118 orbitals, corresponding to a FCI dimension of over 1038.

  11. [Drug interactions with grapefruit].

    PubMed

    Bojanić, Zoran Z; Bojanić, Novica Z; Bojanić, Vladmila V

    2010-01-01

    The concentration of many orally given medications may be affected by grapefruit or grapefruit juice consumption. It may result in numerous harmful effects. Taking only one cup of juice may induce interactions with different drugs even during the period of a few days. The effect is induced by suppression of cytochrome P450 isoenzyme CYP3A4 in the intestinal wall. The Latin name of grapefruit, Citrus paradisi, is quite opposite to the effects which could be induced by taking grapefruit and some medications at the same time. It is necessary to avoid taking grapefruit with the drugs whose pharmacokinetics could be altered by the active principles found in that fruit. The coloured grapefruit contains less furanocoumarins, but there is no difference in induction and intensity of pharmacokinetic interaction with drugs related to its colour. Other citrus fruits (orange, lemon) do not have such effects, but some other fruits (pomegranate, stella fruit, banpeiyu, hassaku, takaoka-buntan and kinkan) exert inhibitory effects on the activity of cytochrome P450 isoenzyme.

  12. Interaction between piperazine and chlorpromazine

    PubMed Central

    Sturman, Gillian

    1974-01-01

    The interaction between piperazine and chlorpromazine has been studied in rats and mice. Piperazine administered a few hours previously potentiated the action of chlorpromazine on the central nervous system. No such interaction was found between piperazine and prochlorperazine. PMID:4856722

  13. Mediated Discourse and Social Interaction.

    ERIC Educational Resources Information Center

    Scollon, Ron

    1999-01-01

    Suggests that future research in language and social interaction should (1) focus on studies of media or mediated discourse as forms of social interaction as one broad group; and (2) engage in the flow of postmodernist discourse. (Author/VWL)

  14. How Interactive Is Your Whiteboard?

    ERIC Educational Resources Information Center

    Tanner, Howard; Jones, Sonia

    2007-01-01

    In this article, the authors question the assumption that interactive whiteboards (IWBs) automatically lead to interactive teaching. The authors contend that although IWBs have features that offer great potential for the development of highly interactive teaching approaches, it may be the case that teachers must have made the transition from…

  15. An Introduction to Interactive Video.

    ERIC Educational Resources Information Center

    Chung, Ulric

    Aspects of interactive video use in the second language classroom are examined. The major components and equipment considerations for an interactive videodisk and computer system are outlined, including factors in the choice of a system interface. The use and control of interactive video for accessing scenes to be played are described, and…

  16. Expanding the Interaction Equivalency Theorem

    ERIC Educational Resources Information Center

    Rodriguez, Brenda Cecilia Padilla; Armellini, Alejandro

    2015-01-01

    Although interaction is recognised as a key element for learning, its incorporation in online courses can be challenging. The interaction equivalency theorem provides guidelines: Meaningful learning can be supported as long as one of three types of interactions (learner-content, learner-teacher and learner-learner) is present at a high level. This…

  17. Interactive Writing with Young Children.

    ERIC Educational Resources Information Center

    Hall, Nigel

    2000-01-01

    Defines interactive writing and how it works. Recommends starting with the message sheet, then going on to written conversation and writing to a make-believe character. Identifies six benefits of interactive writing and asserts that interactive writing supports a basic human need of expressing one's thoughts and communicating them to others. (DLH)

  18. Imagined Interactions and the Family.

    ERIC Educational Resources Information Center

    Rosenblatt, Paul C.; Meyer, Cynthia

    1986-01-01

    The forms and functions of imagined interaction are discussed. Imagined interaction aids in the clarification of thinking, in dealing with unfinished and emergent relationship business, in preparing for a possibly difficult interaction, and in dealing with opposing aspects of self. (Author/BL)

  19. Ridge Regression for Interactive Models.

    ERIC Educational Resources Information Center

    Tate, Richard L.

    1988-01-01

    An exploratory study of the value of ridge regression for interactive models is reported. Assuming that the linear terms in a simple interactive model are centered to eliminate non-essential multicollinearity, a variety of common models, representing both ordinal and disordinal interactions, are shown to have "orientations" that are…

  20. Human-Robot Interaction

    NASA Technical Reports Server (NTRS)

    Sandor, Aniko; Cross, E. Vincent, II; Chang, Mai Lee

    2015-01-01

    Human-robot interaction (HRI) is a discipline investigating the factors affecting the interactions between humans and robots. It is important to evaluate how the design of interfaces affect the human's ability to perform tasks effectively and efficiently when working with a robot. By understanding the effects of interface design on human performance, workload, and situation awareness, interfaces can be developed to appropriately support the human in performing tasks with minimal errors and with appropriate interaction time and effort. Thus, the results of research on human-robot interfaces have direct implications for the design of robotic systems. For efficient and effective remote navigation of a rover, a human operator needs to be aware of the robot's environment. However, during teleoperation, operators may get information about the environment only through a robot's front-mounted camera causing a keyhole effect. The keyhole effect reduces situation awareness which may manifest in navigation issues such as higher number of collisions, missing critical aspects of the environment, or reduced speed. One way to compensate for the keyhole effect and the ambiguities operators experience when they teleoperate a robot is adding multiple cameras and including the robot chassis in the camera view. Augmented reality, such as overlays, can also enhance the way a person sees objects in the environment or in camera views by making them more visible. Scenes can be augmented with integrated telemetry, procedures, or map information. Furthermore, the addition of an exocentric (i.e., third-person) field of view from a camera placed in the robot's environment may provide operators with the additional information needed to gain spatial awareness of the robot. Two research studies investigated possible mitigation approaches to address the keyhole effect: 1) combining the inclusion of the robot chassis in the camera view with augmented reality overlays, and 2) modifying the camera

  1. IDG - INTERACTIVE DIF GENERATOR

    NASA Technical Reports Server (NTRS)

    Preheim, L. E.

    1994-01-01

    The Interactive DIF Generator (IDG) utility is a tool used to generate and manipulate Directory Interchange Format files (DIF). Its purpose as a specialized text editor is to create and update DIF files which can be sent to NASA's Master Directory, also referred to as the International Global Change Directory at Goddard. Many government and university data systems use the Master Directory to advertise the availability of research data. The IDG interface consists of a set of four windows: (1) the IDG main window; (2) a text editing window; (3) a text formatting and validation window; and (4) a file viewing window. The IDG main window starts up the other windows and contains a list of valid keywords. The keywords are loaded from a user-designated file and selected keywords can be copied into any active editing window. Once activated, the editing window designates the file to be edited. Upon switching from the editing window to the formatting and validation window, the user has options for making simple changes to one or more files such as inserting tabs, aligning fields, and indenting groups. The viewing window is a scrollable read-only window that allows fast viewing of any text file. IDG is an interactive tool and requires a mouse or a trackball to operate. IDG uses the X Window System to build and manage its interactive forms, and also uses the Motif widget set and runs under Sun UNIX. IDG is written in C-language for Sun computers running SunOS. This package requires the X Window System, Version 11 Revision 4, with OSF/Motif 1.1. IDG requires 1.8Mb of hard disk space. The standard distribution medium for IDG is a .25 inch streaming magnetic tape cartridge in UNIX tar format. It is also available on a 3.5 inch diskette in UNIX tar format. The program was developed in 1991 and is a copyrighted work with all copyright vested in NASA. SunOS is a trademark of Sun Microsystems, Inc. X Window System is a trademark of Massachusetts Institute of Technology. OSF/Motif is a

  2. Bunyavirus-vector interactions.

    PubMed

    Beaty, B J; Bishop, D H

    1988-06-01

    Recent advances in the genetics and molecular biology of bunyaviruses have been applied to understanding bunyavirus-vector interactions. Such approaches have revealed which virus gene and gene products are important in establishing infections in vectors and in transmission of viruses. However, much more information is required to understand the molecular mechanisms of persistent infections of vectors which are lifelong but apparently exert no untoward effect. In fact, it seems remarkable that LAC viral antigen can be detected in almost every cell in an ovarian follicle, yet no untoward effect on fecundity and no teratology is seen. Similarly the lifelong infection of the vector would seem to provide ample opportunity for bunyavirus evolution by genetic drift and, under the appropriate circumstances, by segment reassortment. The potential for bunyavirus evolution by segment reassortment in vectors certainly exists. For example the Group C viruses in a small forest in Brazil seem to constitute a gene pool, with the 6 viruses related alternately by HI/NT and CF reactions, which assay respectively M RNA and S RNA gene products (Casals and Whitman, 1960; Shope and Causey, 1962). Direct evidence for naturally occurring reassortant bunyaviruses has also been obtained. Oligonucleotide fingerprint analyses of field isolates of LAC virus and members of the Patois serogroup of bunyaviruses have demonstrated that reassortment does occur in nature (El Said et al., 1979; Klimas et al., 1981; Ushijima et al., 1981). Determination of the genotypic frequencies of viruses selected by the biological interactions of viruses and vectors after dual infection and segment reassortment is an important issue. Should a virus result that efficiently interacts with alternate vector species, the virus could be expressed in different circumstances with serious epidemiologic consequences. Dual infection of vectors with different viruses is not unlikely, because many bunyaviruses are sympatric in

  3. Interactive molecular dynamics

    NASA Astrophysics Data System (ADS)

    Schroeder, Daniel V.

    2015-03-01

    Physics students now have access to interactive molecular dynamics simulations that can model and animate the motions of hundreds of particles, such as noble gas atoms, that attract each other weakly at short distances but repel strongly when pressed together. Using these simulations, students can develop an understanding of forces and motions at the molecular scale, nonideal fluids, phases of matter, thermal equilibrium, nonequilibrium states, the Boltzmann distribution, the arrow of time, and much more. This article summarizes the basic features and capabilities of such a simulation, presents a variety of student exercises using it at the introductory and intermediate levels, and describes some enhancements that can further extend its uses. A working simulation code, in html5 and javascript for running within any modern Web browser, is provided as an online supplement.

  4. Parvovirus Glycan Interactions

    PubMed Central

    Huang, Lin-Ya; Halder, Sujata; Agbandje-McKenna, Mavis

    2014-01-01

    Members of the Parvoviridae utilize glycan receptors for cellular attachment and subsequent interactions determine transduction efficiency or pathogenic outcome. This review focuses on the identity of the glycan receptors utilized, their capsid binding footprints, and a discussion of the overlap of these sites with tropism, transduction, and pathogenicity determinants. Despite high sequence diversity between the different genera, most parvoviruses bind to negatively charged glycans, such as sialic acid and heparan sulfate, abundant on cell surface membranes. The capsid structure of these viruses exhibit high structural homology enabling common regions to be utilized for glycan binding and at the same time the sequence diversity at the common footprints allows for binding of different glycans or differential binding of the same glycan. PMID:25047752

  5. Interactions of astringent substances.

    PubMed

    Lawless, H T; Corrigan, C J; Lee, C B

    1994-04-01

    Two-component mixtures of astringent materials were rated for perceived intensity of astringent and taste attributes over time. Components included alum (a complex salt), gallic acid (the monomeric component of hydrolyzable tannins), catechin (the monomeric component of condensed tannins) and citric acid. Mixtures of alum and gallic acid showed mixture suppression, in that the 50/50 mixture was less intense than either component in astringency, drying, roughing and puckery/drawing sensations. Suppression was seen at concentration levels producing moderate to strong astringency but was absent or less pronounced at lower concentration levels. A similar pattern held for citric acid, although the suppressive effects were less pronounced. Catechin and gallic acid mixtures were additive. Sensory interactions between astringent materials appears to depend on the substances involved and their concentrations (or intensity levels).

  6. Parvovirus glycan interactions.

    PubMed

    Huang, Lin-Ya; Halder, Sujata; Agbandje-McKenna, Mavis

    2014-08-01

    Members of the Parvoviridae utilize glycan receptors for cellular attachment and subsequent interactions determine transduction efficiency or pathogenic outcome. This review focuses on the identity of the glycan receptors utilized, their capsid binding footprints, and a discussion of the overlap of these sites with tropism, transduction, and pathogenicity determinants. Despite high sequence diversity between the different genera, most parvoviruses bind to negatively charged glycans, such as sialic acid and heparan sulfate, abundant on cell surface membranes. The capsid structure of these viruses exhibit high structural homology enabling common regions to be utilized for glycan binding. At the same time the sequence diversity at the common footprints allows for binding of different glycans or differential binding of the same glycan.

  7. Interactive TV Narrativity

    NASA Astrophysics Data System (ADS)

    Ursu, Marian F.

    Looking back over the past 25 years, the impressive developments in information and communication technologies generated a booming popularity of the new forms of media consumption that allow for interactivity and mobility, such as Web information and entertainment and games. This was and still is particularly evident within the younger generation, who are the most avid adopters of both new technologies and new forms of media consumption (Schadler 2006; KPMG 2007). When asked, in 2006, which device they could not live without, 37% mentioned their PC, 26% their mobile phone, whereas only 17% mentioned their TVs (Schadler 2006); and all these were before the launch of products such as the iPhone, which offer increasing flexibility and mobility of the media experiences.

  8. Fluid structure interaction

    NASA Astrophysics Data System (ADS)

    Komatsu, K.

    A few nonflow field problems are considered, taking into account mainly fluid-shell dynamic interaction and fluid-solid impact. Fluid-shell systems are used as models for sloshing and POGO (structure-propulsion coupling oscillation) in liquid rockets, floating lids of oil tanks, large tanks containing fluid, nuclear containment vessels, and head injury studies in biomechanics. The study of structure-water impact finds applications in the problems associated with water landings of reentry vehicles, water entry of torpedoes, and slamming of ships in heavy seas. At least three different methods can be used in handling wet structures. Attention is given to the method which treats fluid by boundary elements and structure by finite elements.

  9. Universality in string interactions

    NASA Astrophysics Data System (ADS)

    Huang, Yu-tin; Schlotterer, Oliver; Wen, Congkao

    2016-09-01

    In this note, we provide evidence for universality in the low-energy expansion of tree-level string interactions. More precisely, in the α'-expansion of tree-level scattering amplitudes, we conjecture that the leading transcendental coefficient at each order in α' is universal for all perturbative string theories. We have checked this universality up to seven points and trace its origin to the ability to restructure the disk integrals of open bosonic string into those of the superstring. The accompanying kinematic functions have the same low-energy limit and do not introduce any transcendental numbers in their α'-corrections. Universality in the closed-string sector then follows from KLT-relations.

  10. Three dimensional interactive display

    NASA Technical Reports Server (NTRS)

    Vranish, John M. (Inventor)

    2005-01-01

    A three-dimensional (3-D) interactive display and method of forming the same, includes a transparent capaciflector (TC) camera formed on a transparent shield layer on the screen surface. A first dielectric layer is formed on the shield layer. A first wire layer is formed on the first dielectric layer. A second dielectric layer is formed on the first wire layer. A second wire layer is formed on the second dielectric layer. Wires on the first wire layer and second wire layer are grouped into groups of parallel wires with a turnaround at one end of each group and a sensor pad at the opposite end. An operational amplifier is connected to each of the sensor pads and the shield pad biases the pads and receives a signal from connected sensor pads in response to intrusion of a probe. The signal is proportional to probe location with respect to the monitor screen.

  11. Synchronization and hydrodynamic interactions

    NASA Astrophysics Data System (ADS)

    Powers, Thomas; Qian, Bian; Breuer, Kenneth

    2008-03-01

    Cilia and flagella commonly beat in a coordinated manner. Examples include the flagella that Volvox colonies use to move, the cilia that sweep foreign particles up out of the human airway, and the nodal cilia that set up the flow that determines the left-right axis in developing vertebrate embryos. In this talk we present an experimental study of how hydrodynamic interactions can lead to coordination in a simple idealized system: two nearby paddles driven with fixed torques in a highly viscous fluid. The paddles attain a synchronized state in which they rotate together with a phase difference of 90 degrees. We discuss how synchronization depends on system parameters and present numerical calculations using the method of regularized stokeslets.

  12. Critical Density Interaction Studies

    SciTech Connect

    Young, P; Baldis, H A; Cheung, P; Rozmus, W; Kruer, W; Wilks, S; Crowley, S; Mori, W; Hansen, C

    2001-02-14

    Experiments have been performed to study the propagation of intense laser pulses to high plasma densities. The issue of self-focusing and filamentation of the laser pulse as well as developing predictive capability of absorption processes and x-ray conversion efficiencies is important for numerous programs at the Laboratory, particularly Laser Program (Fast Ignitor and direct-drive ICF) and D&NT (radiography, high energy backlighters and laser cutting). Processes such as resonance absorption, profile modification, linear mode conversion, filamentation and stimulated Brillouin scattering can occur near the critical density and can have important effects on the coupling of laser light to solid targets. A combination of experiments have been used to study the propagation of laser light to high plasma densities and the interaction physics of intense laser pulses with solid targets. Nonparaxial fluid codes to study nonstationary behavior of filamentation and stimulated Brillouin scattering at high densities have also been developed as part of this project.

  13. Interacting neural networks

    NASA Astrophysics Data System (ADS)

    Metzler, R.; Kinzel, W.; Kanter, I.

    2000-08-01

    Several scenarios of interacting neural networks which are trained either in an identical or in a competitive way are solved analytically. In the case of identical training each perceptron receives the output of its neighbor. The symmetry of the stationary state as well as the sensitivity to the used training algorithm are investigated. Two competitive perceptrons trained on mutually exclusive learning aims and a perceptron which is trained on the opposite of its own output are examined analytically. An ensemble of competitive perceptrons is used as decision-making algorithms in a model of a closed market (El Farol Bar problem or the Minority Game. In this game, a set of agents who have to make a binary decision is considered.); each network is trained on the history of minority decisions. This ensemble of perceptrons relaxes to a stationary state whose performance can be better than random.

  14. Tracking protein aggregate interactions

    PubMed Central

    Bartz, Jason C; Nilsson, K Peter R

    2011-01-01

    Amyloid fibrils share a structural motif consisting of highly ordered β-sheets aligned perpendicular to the fibril axis.1, 2 At each fibril end, β-sheets provide a template for recruiting and converting monomers.3 Different amyloid fibrils often co-occur in the same individual, yet whether a protein aggregate aids or inhibits the assembly of a heterologous protein is unclear. In prion disease, diverse prion aggregate structures, known as strains, are thought to be the basis of disparate disease phenotypes in the same species expressing identical prion protein sequences.4–7 Here we explore the interactions reported to occur when two distinct prion strains occur together in the central nervous system. PMID:21597336

  15. Interactive Data Visualization

    SciTech Connect

    Steed, Chad A

    2017-01-01

    Interactive data visualization leverages human visual perception and cognition to improve the accuracy and effectiveness of data analysis. When combined with automated data analytics, data visualization systems orchestrate the strengths of humans with the computational power of machines to solve problems neither approach can manage in isolation. In the intelligent transportation system domain, such systems are necessary to support decision making in large and complex data streams. In this chapter, we provide an introduction to several key topics related to the design of data visualization systems. In addition to an overview of key techniques and strategies, we will describe practical design principles. The chapter is concluded with a detailed case study involving the design of a multivariate visualization tool.

  16. Drugging Membrane Protein Interactions

    PubMed Central

    Yin, Hang; Flynn, Aaron D.

    2016-01-01

    The majority of therapeutics target membrane proteins, accessible on the surface of cells, to alter cellular signaling. Cells use membrane proteins to transduce signals into cells, transport ions and molecules, bind the cell to a surface or substrate, and catalyze reactions. Newly devised technologies allow us to drug conventionally “undruggable” regions of membrane proteins, enabling modulation of protein–protein, protein–lipid, and protein–nucleic acid interactions. In this review, we survey the state of the art in high-throughput screening and rational design in drug discovery, and we evaluate the advances in biological understanding and technological capacity that will drive pharmacotherapy forward against unorthodox membrane protein targets. PMID:26863923

  17. Glycosaminoglycan-lipoprotein interaction.

    PubMed

    Olsson, U; Ostergren-Lundén, G; Moses, J

    2001-10-01

    Glycosaminoglycans (GAGs) bound to various proteoglycans (PGs) present in the cardiovascular system have been proposed to perform a wide range of functions. These include conferring viscoelastic properties; interacting with and modulating growth factors and enzymes; and as receptors and co-receptors in lipoprotein metabolism. Binding of apoB-100 lipoproteins, particularly low density lipoproteins (LDL), to GAGs of extracellular matrix PGs in arteries has been proposed to be an initiating event in development of atherosclerosis. This study was initiated with the aim of getting an overview of the binding patterns of different lipoprotein subclasses with individual GAG categories. We thus evaluated the interaction of lipoproteins with GAGs commonly found in the cardiovascular system using a gel mobility-shift assay developed for this purpose. The same procedure was used to measure lipoproteins binding to metabolically [(35)S]-labeled whole PGs prepared from three cell types, arterial smooth muscle cells, THP-1 macrophages and from HepG2 cells. The effect of GAG composition on PGs on lipoprotein binding was evaluated by enzymatic degradation of the carbohydrate chains. Heparan sulfate was found to bind beta very low density lipoproteins (beta-VLDL) and a chylomicron remnant model (beta-VLDL+apoE), but not LDL. Dermatan sulfate was found to bind LDL, but not beta-VLDL or the chylomicron remnant model. Chondroitin sulfate and heparin were found to bind all lipoproteins tested (LDL, beta-VLDL and beta-VLDL+apoE) although with different affinities. We can conclude that each lipoprotein subclass tested binds a specific assortment of the GAGs tested. The observations made contribute to the understanding of new and complex mechanisms by which carbohydrate and lipid metabolism may be linked.

  18. [Neuron-glia interactions].

    PubMed

    Belin, M F; Hardin, H

    1991-01-01

    The progress of research in the Central Nervous System (CNS) had led to the consideration of neurons and glia as indissociable functional complexes. Neuron-glia interactions are essential for the maturation of the CNS. Glial cells release trophic factors for neurons (NGF) and neurons release trophic factors for glia (GGF). Furthermore, the latter provide a substrate for the migration of neurons and guidance of axons by mean of adhesion molecules. In adults, the interactions between neurons and glial cells serve to maintain homeostasis. Thus, the glial cells perform the restoration of the metabolic equilibrium overthrown by the transmission of the nerve impulse and provide the glucose required for neuronal activity. The nerve impulse provokes increases in the cellular space of CO2, K+, NH3 and neurotransmitters which must be taken up to allow neuronal activity to continue (in normal conditions). Astrocytes perform the uptake of the extracellular K+ by means of passive ionic channels, ionic voltage-dependent channels and a sodium-potassium-ATPase-dependent pump. The oligodendrocytes are involved in the metabolism of CO2 by converting CO2 into carbonic acid by means of carbonic anhydrase. Oligodendrocytes and astrocytes play a role in terminating neural transmission by the uptake of the amino acid neurotransmitters, such as GABA, glutamate and aspartate. The catabolism of glutamate to glutamine by means of glutamine synthetase allows both the conversion of an excitatory amino acid into a neutral amino acid (which can diffuse in the extracellular space without causing neural transmission) and the reduction of cerebral NH3 content.(ABSTRACT TRUNCATED AT 250 WORDS)

  19. [Encouraging experiences of interactive lectures].

    PubMed

    Lehtonen, Sanna; Linden, Anni-Maija; Ojala, Päivi M; Polvi, Anne; Sallinen, Ville; Viranta, Suvi

    2009-01-01

    Traditional lectures typically represent unidirectional transfer of information from teacher to students whilst interactive lectures involve student activity. We analyzed the experiences of students and teachers of interactive lectures by observation and questionnaires during a course organized by Helsinki Biomedical Graduate School. Teachers and the majority of students found interactive lectures highly motivating although we observed that only a fraction of students participated in discussions. Students were of the opinion that interactivity improved their learning. Supplementing lectures with interactive elements encourages students to adopt active learning techniques.

  20. Making public displays interactive everywhere.

    PubMed

    Boring, Sebastian; Baur, Dominikus

    2013-01-01

    As the number of large public displays increases, the need for interaction techniques to control them is emerging. One promising way to provide such interaction is through personal mobile devices. However, although much research has covered this topic, it hasn't yet brought those technologies fully into the public that is, by allowing for interactions in a variety of public spaces. A proposed tracking technology has led to several prototype applications that employ mobile devices to interact with large public displays. In turn, these prototypes have led to an overarching interaction concept that allows for public deployment regardless of the space's characteristics (for example, layout and technologies).

  1. Polymer-Nucleic Acid Interactions.

    PubMed

    Shen, Zhuang-Lin; Xia, Yi-Qi; Yang, Qiu-Song; Tian, Wen-de; Chen, Kang; Ma, Yu-Qiang

    2017-04-01

    Gene therapy is an important therapeutic strategy in the treatment of a wide range of genetic disorders. Polymers forming stable complexes with nucleic acids (NAs) are non-viral gene carriers. The self-assembly of polymers and nucleic acids is typically a complex process that involves many types of interaction at different scales. Electrostatic interaction, hydrophobic interaction, and hydrogen bonds are three important and prevalent interactions in the polymer/nucleic acid system. Electrostatic interactions and hydrogen bonds are the main driving forces for the condensation of nucleic acids, while hydrophobic interactions play a significant role in the cellular uptake and endosomal escape of polymer-nucleic acid complexes. To design high-efficiency polymer candidates for the DNA and siRNA delivery, it is necessary to have a detailed understanding of the interactions between them in solution. In this chapter, we survey the roles of the three important interactions between polymers and nucleic acids during the formation of polyplexes and summarize recent understandings of the linear polyelectrolyte-NA interactions and dendrimer-NA interactions. We also review recent progress optimizing the gene delivery system by tuning these interactions.

  2. Developing a general interaction potential for hydrophobic and hydrophilic interactions.

    PubMed

    Donaldson, Stephen H; Røyne, Anja; Kristiansen, Kai; Rapp, Michael V; Das, Saurabh; Gebbie, Matthew A; Lee, Dong Woog; Stock, Philipp; Valtiner, Markus; Israelachvili, Jacob

    2015-02-24

    We review direct force measurements on a broad class of hydrophobic and hydrophilic surfaces. These measurements have enabled the development of a general interaction potential per unit area, W(D) = -2γ(i)Hy exp(-D/D(H)) in terms of a nondimensional Hydra parameter, Hy, that applies to both hydrophobic and hydrophilic interactions between extended surfaces. This potential allows one to quantitatively account for additional attractions and repulsions not included in the well-known combination of electrostatic double layer and van der Waals theories, the so-called Derjaguin-Landau-Verwey-Overbeek (DLVO) theory. The interaction energy is exponentially decaying with decay length D(H) ≈ 0.3-2 nm for both hydrophobic and hydrophilic interactions, with the exact value of D(H) depending on the precise system and conditions. The pre-exponential factor depends on the interfacial tension, γ(i), of the interacting surfaces and Hy. For Hy > 0, the interaction potential describes interactions between partially hydrophobic surfaces, with the maximum hydrophobic interaction (i.e., two fully hydrophobic surfaces) corresponding to Hy = 1. Hydrophobic interactions between hydrophobic monolayer surfaces measured with the surface forces apparatus (SFA) are shown to be well described by the proposed interaction potential. The potential becomes repulsive for Hy < 0, corresponding to partially hydrophilic (hydrated) interfaces. Hydrated surfaces such as mica, silica, and lipid bilayers are discussed and reviewed in the context of the values of Hy appropriate for each system.

  3. Discovering interacting domains and motifs in protein-protein interactions.

    PubMed

    Hugo, Willy; Sung, Wing-Kin; Ng, See-Kiong

    2013-01-01

    Many important biological processes, such as the signaling pathways, require protein-protein interactions (PPIs) that are designed for fast response to stimuli. These interactions are usually transient, easily formed, and disrupted, yet specific. Many of these transient interactions involve the binding of a protein domain to a short stretch (3-10) of amino acid residues, which can be characterized by a sequence pattern, i.e., a short linear motif (SLiM). We call these interacting domains and motifs domain-SLiM interactions. Existing methods have focused on discovering SLiMs in the interacting proteins' sequence data. With the recent increase in protein structures, we have a new opportunity to detect SLiMs directly from the proteins' 3D structures instead of their linear sequences. In this chapter, we describe a computational method called SLiMDIet to directly detect SLiMs on domain interfaces extracted from 3D structures of PPIs. SLiMDIet comprises two steps: (1) interaction interfaces belonging to the same domain are extracted and grouped together using structural clustering and (2) the extracted interaction interfaces in each cluster are structurally aligned to extract the corresponding SLiM. Using SLiMDIet, de novo SLiMs interacting with protein domains can be computationally detected from structurally clustered domain-SLiM interactions for PFAM domains which have available 3D structures in the PDB database.

  4. Interactive Projector as an Interactive Teaching Tool in the Classroom: Evaluating Teaching Efficiency and Interactivity

    ERIC Educational Resources Information Center

    Liu, Li-Ying; Cheng, Meng-Tzu

    2015-01-01

    This study reports on a measurement that is used to investigate interactivity in the classrooms and examines the impact of integrating the interactive projector into middle school science classes on classroom interactivity and students' biology learning. A total of 126 7th grade Taiwanese students were involved in the study and quasi-experimental…

  5. Weak Interactions and Instability Cascades.

    PubMed

    Kadoya, Taku; McCann, Kevin S

    2015-07-29

    Food web theory states that a weak interactor which is positioned in the food web such that it tends to deflect, or mute, energy away from a potentially oscillating consumer-resource interaction often enhances community persistence and stability. Here we examine how adding other weak interactions (predation/harvesting) on the stabilizing weak interactor alters the stability of food web using a set of well-established food web models/modules. We show that such "weak on weak" interaction chains drive an indirect dynamic cascade that can rapidly ignite a distant consumer-resource oscillator. Nonetheless, we also show that the "weak on weak" interactions are still more stable than the food web without them, and so weak interactions still generally act to stabilize food webs. Rather, these results are best interpreted to say that the degree of the stabilizing effect of a given important weak interaction can be severely compromised by other weak interactions (including weak harvesting).

  6. Arc electrode interaction study

    NASA Technical Reports Server (NTRS)

    Zhou, X.; Berns, D.; Heberlein, J.

    1994-01-01

    The project consisted of two parts: (1) the cathode interaction studies which were a continuation of previous work and had the objective of increasing our understanding of the microscopic phenomena controlling cathode erosion in arc jet thrusters, and (2) the studies of the anode attachment in arc jet thrusters. The cathode interaction studies consisted of (1) a continuation of some modeling work in which the previously derived model for the cathode heating was applied to some specific gases and electrode materials, and (2) experimental work in which various diagnostics was applied to the cathode. The specific diagnostics used were observation of the cathode tip during arcing using a Laser Strobe Video system in conjunction with a tele-microscope, a monochromator with an optical multichannel analyzer for the determination of the cathode temperature distribution, and various ex situ materials analysis methods. The emphasis of our effort was shifted to the cathode materials analysis because a parallel project was in place during the second half of 1993 with a visiting scientist pursuing arc electrode materials studies. As a consequence, the diagnostic investigations of the arc in front of the cathode had to be postponed to the first half of 1994, and we are presently preparing these measurements. The results of last year's study showed some unexpected effects influencing the cathode erosion behavior, such as increased erosion away from the cathode tip, and our understanding of these effects should improve our ability to control cathode erosion. The arc jet anode attachment studies concentrated on diagnostics of the instabilities in subsonic anode attachment arc jet thrusters, and were supplemental measurements to work which was performed by one of the authors who spent the summer as an intern at NASA Lewis Research Center. A summary of the results obtained during the internship are included because they formed an integral part of the study. Two tasks for 1994, the

  7. "Interactive Classification Technology"

    NASA Technical Reports Server (NTRS)

    deBessonet, Cary

    1999-01-01

    The investigators are upgrading a knowledge representation language called SL (Symbolic Language) and an automated reasoning system called SMS (Symbolic Manipulation System) to enable the technologies to be used in automated reasoning and interactive classification systems. The overall goals of the project are: a) the enhancement of the representation language SL to accommodate multiple perspectives and a wider range of meaning; b) the development of a sufficient set of operators to enable the interpreter of SL to handle representations of basic cognitive acts; and c) the development of a default inference scheme to operate over SL notation as it is encoded. As to particular goals the first-year work plan focused on inferencing and.representation issues, including: 1) the development of higher level cognitive/ classification functions and conceptual models for use in inferencing and decision making; 2) the specification of a more detailed scheme of defaults and the enrichment of SL notation to accommodate the scheme; and 3) the adoption of additional perspectives for inferencing.

  8. SEEPAGE/BACKFILL INTERACTIONS

    SciTech Connect

    P. Mariner

    2000-04-14

    As directed by written development plan (CRWMS M&O 1999a), a sub-model of seepage/backfill interactions is developed and presented in this document to support the Engineered Barrier System (EBS) Physical and Chemical Environment Model. The purpose of this analysis is to assist Performance Assessment Operations (PAO) and the Engineered Barrier Performance Department in modeling the geochemical environment within a repository drift. In this analysis, a conceptual model is developed to provide PAO a more detailed and complete in-drift geochemical model abstraction and to answer the key technical issues (KTI) raised in the NRC Issue Resolution Status Report (IRSR) for the Evolution of the Near Field Environment (NFE) Revision 2 (NRC 1999). The development plan calls for a sub-model that evaluates the effect on water chemistry of chemical reactions between water that enters the drift and backfill materials in the drift. The development plan specifically requests an evaluation of the following important chemical reaction processes: dissolution-precipitation, aqueous complexation, and oxidation-reduction. The development plan also requests the evaluation of the effects of varying seepage and drainage fluxes, varying temperature, and varying evaporation and condensation fluxes. Many of these effects are evaluated in a separate Analysis/Model Report (AMR), ''Precipitates Salts Analysis AMR'' (CRWMS M&O 2000), so the results of that AMR are referenced throughout this AMR.

  9. Hydrogen interactions with metals

    NASA Technical Reports Server (NTRS)

    Mclellan, R. B.; Harkins, C. G.

    1975-01-01

    Review of the literature on the nature and extent of hydrogen interactions with metals and the role of hydrogen in metal failure. The classification of hydrogen-containing systems is discussed, including such categories as covalent hydrides, volatile hydrides, polymeric hydrides, and transition metal hydride complexes. The use of electronegativity as a correlating parameter in determining hydride type is evaluated. A detailed study is made of the thermodynamics of metal-hydrogen systems, touching upon such aspects as hydrogen solubility, the positions occupied by hydrogen atoms within the solvent metal lattice, the derivation of thermodynamic functions of solid solutions from solubility data, and the construction of statistical models for hydrogen-metal solutions. A number of theories of hydrogen-metal bonding are reviewed, including the rigid-band model, the screened-proton model, and an approach employing the augmented plane wave method to solve the one-electron energy band problem. Finally, the mechanism of hydrogen embrittlement is investigated on the basis of literature data concerning stress effects and the kinetics of hydrogen transport to critical sites.

  10. Atmospheric Ball Plasma Interactions

    NASA Astrophysics Data System (ADS)

    Wurden, C. J. V.; Wurden, G. A.

    2008-11-01

    Free-floating atmospheric pressure copper hydroxyl ball plasmas have been studied in air and helium atmospheres, using still and high speed photography (up to 20,000 fps), collimated photodiodes, and spectroscopy. A fine boundary layer between the greenish Cu-OH cloud, and the air, is orange in color. However, when the discharge is initiated into a helium atmosphere, the boundary layer is no longer visible, suggesting that the visible boundary was caused by interactions with oxygen. We have studied scaling of the 10-cm diameter ball plasmas with both the size of the water bucket, and the applied discharge voltage, over the range of 500-5000 volts. When looking at the initial spider-leg breakdown above the water surface, the ratio of H-alpha to H-beta lines suggests a temperature of ˜0.3 eV. This is also consistent with the presence of molecular lines of OH, and perhaps CuOH2 in the rising cloud. The cloud is affected by, but can penetrate through an aluminum window screen mesh.

  11. Interactions between electromagnetic fields

    NASA Astrophysics Data System (ADS)

    Schwan, H. P.

    1985-02-01

    We applied for this grant to support a workshop at Erice, Italy. This workshop has been commonly called Erice School and the main subject of this workshop is the interaction of electromagnetic fields with biological cells and molecules. The grant from ONR enabled us to invite American scientists to participants in this workshop and deliver scientific papers. The duration of the Erice School was ten days. Therefore, we had sufficient time to discuss the problems of electromagnetic radiations. Vigorous discussions took place during official sessions and during private conversations. The participants of this workshop are mostly those who have been active in the research on bioelectromagnetics, but there are some numbers of speakers who discussed the basic electrical and magnetic properties of polyelectrolytes, biological membranes and tissue. The workshop was unique in that there were participants with a variety of training backgrounds. This enabled us to exchange the information between applied scientists and basic scientists. Also, active exchanges of opinions took place between biological scientists and physical scientists.

  12. Electron Interactions in Graphene

    NASA Astrophysics Data System (ADS)

    Kim, Philip

    2011-03-01

    Electrons confined in two dimensions (2D) can exhibit strongly correlated states. Recent experimental discovery of integer and fractional quantum Hall effect in graphene amplified interest in correlated 2D electronic systems, owning to presence of the unusual topological phase associated with zero effective mass of charge carriers. In this talk, we will discuss the role of the many-body effects due to the electron-electron interaction in graphene manifested in electron transport phenomena. In particular, we will discuss the nature unusual spontaneous symmetry breaking Landau levels graphene under the extreme quantum condition, the appearance of unique low density insulating states and fractional quantum Hall states. Employing extremely high quality samples obtained by suspending graphene and graphene on atomically flat defect free insulating substrate such as hexa-bron nitride, we now investigate various broken symmetry states under high magnetic field. The nature of these broken symmetry state can be explained generally considering underlying SU(4) symmetry in the single particle level of the Landau levels.

  13. Beam-Beam Interactions

    SciTech Connect

    Sramek, Christopher

    2003-09-05

    At the interaction point of a particle accelerator, various phenomena occur which are known as beam-beam effects. Incident bunches of electrons (or positrons) experience strong electromagnetic fields from the opposing bunches, which leads to electron deflection, beamstrahlung and the creation of electron/positron pairs and hadrons due to two-photon exchange. In addition, the beams experience a ''pinch effect'' which focuses each beam and results in either a reduction or expansion of their vertical size. Finally, if a beam's disruption parameter is too large, the beam can develop a sinusoidal distortion, or two-stream (kink) instability. This project simulated and studied these effects as they relate to luminosity, deflection angles and energy loss in order to optimize beam parameters for the Next Linear Collider (NLC). Using the simulation program Guinea-Pig, luminosity, deflection angle and beam energy data was acquired for different levels of beam offset and distortion. Standard deflection curves and luminosity plots agreed with theoretical models but also made clear the difficulties of e-e- feedback. Simulations emphasizing kink instability in modulated and straight beam collisions followed qualitative behavioral predictions and roughly fit recent analytic calculations. Finally, a study of e-e- collisions under design constraints for the NLC provided new estimates of how luminosity, beamstrahlung energy loss, upsilon parameter and deflection curve width scale with beam spotsizes.

  14. Featured Image: Interacting Galaxies

    NASA Astrophysics Data System (ADS)

    Kohler, Susanna

    2017-06-01

    This beautiful image shows two galaxies, IC 2163 and NGC 2207, as they undergo a grazing collision 114 million light-years away. The image is composite, constructed from Hubble (blue), Spitzer (green), and ALMA (red) data. In a recent study, Debra Elmegreen (Vassar College) and collaborators used this ALMA data to trace the individual molecular clouds in the two interacting galaxies, identifying a total of over 200 clouds that each contain a mass of over a million solar masses. These clouds represent roughly half the molecular gas in the two galaxies total. Elmegreen and collaborators track the properties of these clouds and their relation to star-forming regions observed with Hubble. For more information about their observations, check out the paper linked below.A closer look at the ALMA observations for these galaxies, with the different emission regions labeled. Most of the molecular gas emission comes from the eyelids of IC 2163, and the nuclear ring and Feature i in NGC 2207. [Elmegreen et al. 2017]CitationDebra Meloy Elmegreen et al 2017 ApJ 841 43. doi:10.3847/1538-4357/aa6ba5

  15. Interactive Kalman filtering

    NASA Astrophysics Data System (ADS)

    Bürger, Gerd; Cane, Mark A.

    1994-04-01

    Data assimilation via the extended Kaiman filter can become problematic when the assimilating model is strongly nonlinear, primarily in connection with sharp, "switchlike" changes between different regimes of the system. The filter seems too inert to follow those switches quickly enough, a fact that can lead to a complete failure when the switches occur often enough. In this paper we replace the key feature of the filter, the use of local linearity for the error model update, with a principle that uses a more global approach through the utilization of a set of preselected regimes. The method uses all regime error models simultaneously. Being mutually incompatible, a compromise between the different error models is found through the use of a weighting function that reflects the `closeness' of the error model to the correct model. To test the interactive Kaiman filter a series of numerical experiments is performed using the double-well system and the well-known Lorenz system, and the results are compared to the extended Kaiman filter. It turns out that, depending on the set of preselected regimes, the performance is worse than, comparable to, or better than that of the extended Kaiman filter.

  16. Influenza-Sediment Interactions

    NASA Astrophysics Data System (ADS)

    Trusiak, A.; Block, K. A.; Katz, A.; Gottlieb, P.; Alimova, A.; Galarza, J.; Wei, H.; Steiner, J. C.

    2013-12-01

    A typical water fowl can secrete 1012 influenza virions per day. Therefore it is not unexpected that influenza virions interact with sediments in the water column. The influence of sediments on avian influenza virions is not known. With the threat of avian influenza emerging into the human population, it is crucial to understand virus survivability and residence time in a body of water. Influenza and clay sediments are colloidal particles and thus aggregate as explained by DLVO (Derjaguin & Landau, Verwey & Overbeek) theory. Of great importance is an understanding of the types of particulate or macromolecular components that bind the virus particles, and whether the virus remains biologically active. We present results of hetero-aggregation and transmission electron microscopy experiments performed with influenza A/PR8/38. Influenza particles are suspended with sediment and minimal nutrients for several days, after which the components are evaluated to determine influenza concentration and survivability. Transmission electron microscopy results are reported on the influenza-sediment aggregates to elucidate structure and morphology of the components.

  17. The many faces of interaction.

    PubMed

    Reynolds, P A; Mason, R; Harper, J

    2008-05-24

    During the process of learning teachers and/or students interact with each other on a personal level. However, in e-learning the process is achieved through the intermediary of an information and communication technology (ICT) system or service. Descriptions of these ICT-human interface devices are given in this paper. Successful interaction depends not just on personal relationships, but also on understanding and the ability to use computers and communications equipment effectively. Interactivity, when using ICT, may as a result be different from that in a traditional classroom. The computer is the main man-machine interface and modulates people's ability to interact. Newer, mobile technology will extend the ability to interact in terms of time and place, as is illustrated by the use of portable digital assistants for dental teaching in clinics. The paper concludes that it is very important that both teachers and students should understand how to interact optimally with current and future ICT systems and devices.

  18. Interaction Models for Functional Regression

    PubMed Central

    USSET, JOSEPH; STAICU, ANA-MARIA; MAITY, ARNAB

    2015-01-01

    A functional regression model with a scalar response and multiple functional predictors is proposed that accommodates two-way interactions in addition to their main effects. The proposed estimation procedure models the main effects using penalized regression splines, and the interaction effect by a tensor product basis. Extensions to generalized linear models and data observed on sparse grids or with measurement error are presented. A hypothesis testing procedure for the functional interaction effect is described. The proposed method can be easily implemented through existing software. Numerical studies show that fitting an additive model in the presence of interaction leads to both poor estimation performance and lost prediction power, while fitting an interaction model where there is in fact no interaction leads to negligible losses. The methodology is illustrated on the AneuRisk65 study data. PMID:26744549

  19. Gaussian interaction profile kernels for predicting drug-target interaction.

    PubMed

    van Laarhoven, Twan; Nabuurs, Sander B; Marchiori, Elena

    2011-11-01

    The in silico prediction of potential interactions between drugs and target proteins is of core importance for the identification of new drugs or novel targets for existing drugs. However, only a tiny portion of all drug-target pairs in current datasets are experimentally validated interactions. This motivates the need for developing computational methods that predict true interaction pairs with high accuracy. We show that a simple machine learning method that uses the drug-target network as the only source of information is capable of predicting true interaction pairs with high accuracy. Specifically, we introduce interaction profiles of drugs (and of targets) in a network, which are binary vectors specifying the presence or absence of interaction with every target (drug) in that network. We define a kernel on these profiles, called the Gaussian Interaction Profile (GIP) kernel, and use a simple classifier, (kernel) Regularized Least Squares (RLS), for prediction drug-target interactions. We test comparatively the effectiveness of RLS with the GIP kernel on four drug-target interaction networks used in previous studies. The proposed algorithm achieves area under the precision-recall curve (AUPR) up to 92.7, significantly improving over results of state-of-the-art methods. Moreover, we show that using also kernels based on chemical and genomic information further increases accuracy, with a neat improvement on small datasets. These results substantiate the relevance of the network topology (in the form of interaction profiles) as source of information for predicting drug-target interactions. Software and Supplementary Material are available at http://cs.ru.nl/~tvanlaarhoven/drugtarget2011/. tvanlaarhoven@cs.ru.nl; elenam@cs.ru.nl. Supplementary data are available at Bioinformatics online.

  20. Interactive Raytracing: The nirt Command

    DTIC Science & Technology

    2009-04-01

    Interactive Raytracing : The nirt Command by Clifford Yapp ARL-CR-624 April 2009 prepared by Quantum Research...Laboratory Aberdeen Proving Ground, MD 21005-5068 ARL-CR-624 April 2009 Interactive Raytracing : The nirt Command Clifford Yapp Quantum...DATES COVERED (From - To) June 2008–October 2008 4. TITLE AND SUBTITLE Interactive Raytracing : The nirt Command 5a. CONTRACT NUMBER W911QX-06-F

  1. Collective excitations and retarded interactions

    NASA Astrophysics Data System (ADS)

    Choi, M. Y.; Huberman, B. A.

    1985-03-01

    We study the dynamics of many-body systems with retarded interactions and show how their non-Markovian character can lead to nonergodic behavior. This nonergodicity is characterized by the appearance of long periods or chaotic wanderings in phase space. We construct the phase diagrams for Ising-type systems with delayed interactions, and show the emergence of non-Gibbsian measures as a function of both interaction strengths and delays.

  2. Interactions between Chemokines

    PubMed Central

    Cook, Anna; Hippensteel, Randi; Shimizu, Saori; Nicolai, Jaclyn; Fatatis, Alessandro; Meucci, Olimpia

    2010-01-01

    The soluble form of the chemokine fractalkine/CX3CL1 regulates microglia activation in the central nervous system (CNS), ultimately affecting neuronal survival. This study aims to determine whether CXCL12, another chemokine constitutively expressed in the CNS (known as stromal cell-derived factor 1; SDF-1), regulates cleavage of fractalkine from neurons. To this end, ELISA was used to measure protein levels of soluble fractalkine in the medium of rat neuronal cultures exposed to SDF-1. Gene arrays, quantitative RT-PCR, and Western blot were used to measure overall fractalkine expression in neurons. The data show that the rate of fractalkine shedding in healthy cultures positively correlates with in vitro differentiation and survival. In analogy to non-neuronal cells, metalloproteinases (ADAM10/17) are involved in cleavage of neuronal fractalkine as indicated by studies with pharmacologic inhibitors. Moreover, treatment of the neuronal cultures with SDF-1 stimulates expression of the inducible metalloproteinase ADAM17 and increases soluble fractalkine content in culture medium. The effect of SDF-1 is blocked by an inhibitor of both ADAM10 and -17, but only partially affected by a more specific inhibitor of ADAM10. In addition, SDF-1 also up-regulates expression of the fractalkine gene. Conversely, exposure of neurons to an excitotoxic stimulus (i.e. NMDA) inhibits α-secretase activity and markedly diminishes soluble fractalkine levels, leading to cell death. These results, along with previous findings on the neuroprotective role of both SDF-1 and fractalkine, suggest that this novel interaction between the two chemokines may contribute to in vivo regulation of neuronal survival by modulating microglial neurotoxic properties. PMID:20124406

  3. Studies on Strong Interactions

    NASA Astrophysics Data System (ADS)

    Coriano, Claudio

    Five studies, four in Quantum field theory and one in fermionic molecular dynamics are presented. In the first study, introduced in chapter one and developed in chapter two of this dissertation, we formulate an extension of QCD sum rules to Compton scattering of the pion at intermediate energy. The chapter is based on the research paper Fixed angle pion Compton scattering and QCD sum rules by Prof. George Sterman and the author, which has been submitted for publication as a regular article. In chapter 3 we discuss the relation between traditional bosonic exchange models of nuclear strong interaction and soliton models, in the particular case of the sine-Gordon model. The chapter is based on the research paper "Scattering in soliton models and bosonic exchange descriptions", by R. R. Parwani, H. Yamagishi, I. Zahed and the author, and is published in Phys. Rev. D 45 (1992), 2542. A preprint of this paper (Preprint 1) has been included as an Appendix to the Chapter. In Chapter 4 we discuss aspects of the propagation of quantized fields in classical backgrounds, using the light-cone expansion of the propagator. The chapter is based on the research papers "Electrodynamics in the presence of an axion", published by the author in Modern Physics Letters A 7 (1992), 1253, and on the paper "Singularity of Green's function and the effective action in massive Yang Mills theories, by Prof. H. Yamagishi and the author. This last paper is published in Physical Review D 41 (1990), 3226 and its reprint appears in the final part of the Chapter (Reprint 1). In chapter 5, entitled "On the time dependent Rayleigh-Ritz equations", we discuss aspects of the variational approach to fermionic molecular dynamics. This investigation by R. Parwani, H. Yamagishi and the author has been published in Nucl. Physics A 522 (1991), 591. A preprint of this research paper has been inserted in the final part of the Chapter (Preprint 2).

  4. Nutrition and parasite interaction.

    PubMed

    Coop, R L; Holmes, P H

    1996-01-01

    This overview focuses on the interaction between nutritional status and gastrointestinal nematode infection in ruminants and considers: (i) the influence of the parasite on host metabolism; and (ii) the effect of host nutrition on the establishment and survival of parasite populations, the development of the host-immune response and the pathophysiology of infection. Gastrointestinal nematodes reduce voluntary feed intake and efficiency of feed utilisation, a key feature being an increased endogenous loss of protein into the gastrointestinal tract. Overall there is movement of protein from productive processes into repair of the gastrointestinal tract, synthesis of plasma proteins and mucoprotein production. Although reduction in feed intake is a major factor contributing to the reduced performance of parasitised ruminants, the underlying mechanisms of the anorexia are poorly understood. Supplementation of the diet with additional protein does not appear to affect initial establishment of nematode infections but the pathophysiological consequences are generally more severe on lower planes of protein nutrition. The main effect of protein supplementation is to increase the rate of acquisition of immunity and increase resistance to reinfection and this has been associated with an enhanced cellular immune response in the gastrointestinal mucosa. The unresponsiveness of the young lamb can be improved by dietary protein supplementation. Recent trials have shown that growing sheep offered a free choice between a low and a high protein ration are able to modify their diet selection in order to alleviate the increase in protein requirements which result from gastrointestinal nematode infection. Studies on the influence of nutrition on the expression of genotype have shown that the benefits of a superior genotype are not lost on a low protein diet whereas a high protein diet can partially emeliorate the disadvantages of an inferior genotype. In addition to dietary protein

  5. RIBOSOME-MEMBRANE INTERACTION

    PubMed Central

    Adelman, M. R.; Sabatini, David D.; Blobel, Günter

    1973-01-01

    In a medium of high ionic strength, rat liver rough microsomes can be nondestructively disassembled into ribosomes and stripped membranes if nascent polypeptides are discharged from the bound ribosomes by reaction with puromycin. At 750 mM KCl, 5 mM MgCl2, 50 mM Tris·HCl, pH 7 5, up to 85% of all bound ribosomes are released from the membranes after incubation at room temperature with 1 mM puromycin. The ribosomes are released as subunits which are active in peptide synthesis if programmed with polyuridylic acid. The ribosome-denuded, or stripped, rough microsomes (RM) can be recovered as intact, essentially unaltered membranous vesicles Judging from the incorporation of [3H]puromycin into hot acid-insoluble material and from the release of [3H]leucine-labeled nascent polypeptide chains from bound ribosomes, puromycin coupling occurs almost as well at low (25–100 mM) as at high (500–1000 mM) KCl concentrations. Since puromycin-dependent ribosome release only occurs at high ionic strength, it appears that ribosomes are bound to membranes via two types of interactions: a direct one between the membrane and the large ribosomal subunit (labile at high KCl concentration) and an indirect one in which the nascent chain anchors the ribosome to the membrane (puromycin labile). The nascent chains of ribosomes specifically released by puromycin remain tightly associated with the stripped membranes. Some membrane-bound ribosomes (up to 40%) can be nondestructively released in high ionic strength media without puromycin; these appear to consist of a mixture of inactive ribosomes and ribosomes containing relatively short nascent chains. A fraction (∼15%) of the bound ribosomes can only be released from membranes by exposure of RM to ionic conditions which cause extensive unfolding of ribosomal subunits, the nature and significance of these ribosomes is not clear. PMID:4682341

  6. INCA- INTERACTIVE CONTROLS ANALYSIS

    NASA Technical Reports Server (NTRS)

    Bauer, F. H.

    1994-01-01

    The Interactive Controls Analysis (INCA) program was developed to provide a user friendly environment for the design and analysis of linear control systems, primarily feedback control systems. INCA is designed for use with both small and large order systems. Using the interactive graphics capability, the INCA user can quickly plot a root locus, frequency response, or time response of either a continuous time system or a sampled data system. The system configuration and parameters can be easily changed, allowing the INCA user to design compensation networks and perform sensitivity analysis in a very convenient manner. A journal file capability is included. This stores an entire sequence of commands, generated during an INCA session into a file which can be accessed later. Also included in INCA are a context-sensitive help library, a screen editor, and plot windows. INCA is robust to VAX-specific overflow problems. The transfer function is the basic unit of INCA. Transfer functions are automatically saved and are available to the INCA user at any time. A powerful, user friendly transfer function manipulation and editing capability is built into the INCA program. The user can do all transfer function manipulations and plotting without leaving INCA, although provisions are made to input transfer functions from data files. By using a small set of commands, the user may compute and edit transfer functions, and then examine these functions by using the ROOT_LOCUS, FREQUENCY_RESPONSE, and TIME_RESPONSE capabilities. Basic input data, including gains, are handled as single-input single-output transfer functions. These functions can be developed using the function editor or by using FORTRAN- like arithmetic expressions. In addition to the arithmetic functions, special functions are available to 1) compute step, ramp, and sinusoid functions, 2) compute closed loop transfer functions, 3) convert from S plane to Z plane with optional advanced Z transform, and 4) convert from Z

  7. INCA- INTERACTIVE CONTROLS ANALYSIS

    NASA Technical Reports Server (NTRS)

    Bauer, F. H.

    1994-01-01

    The Interactive Controls Analysis (INCA) program was developed to provide a user friendly environment for the design and analysis of linear control systems, primarily feedback control systems. INCA is designed for use with both small and large order systems. Using the interactive graphics capability, the INCA user can quickly plot a root locus, frequency response, or time response of either a continuous time system or a sampled data system. The system configuration and parameters can be easily changed, allowing the INCA user to design compensation networks and perform sensitivity analysis in a very convenient manner. A journal file capability is included. This stores an entire sequence of commands, generated during an INCA session into a file which can be accessed later. Also included in INCA are a context-sensitive help library, a screen editor, and plot windows. INCA is robust to VAX-specific overflow problems. The transfer function is the basic unit of INCA. Transfer functions are automatically saved and are available to the INCA user at any time. A powerful, user friendly transfer function manipulation and editing capability is built into the INCA program. The user can do all transfer function manipulations and plotting without leaving INCA, although provisions are made to input transfer functions from data files. By using a small set of commands, the user may compute and edit transfer functions, and then examine these functions by using the ROOT_LOCUS, FREQUENCY_RESPONSE, and TIME_RESPONSE capabilities. Basic input data, including gains, are handled as single-input single-output transfer functions. These functions can be developed using the function editor or by using FORTRAN- like arithmetic expressions. In addition to the arithmetic functions, special functions are available to 1) compute step, ramp, and sinusoid functions, 2) compute closed loop transfer functions, 3) convert from S plane to Z plane with optional advanced Z transform, and 4) convert from Z

  8. Theoretical studies of molecular interactions

    SciTech Connect

    Lester, W.A. Jr.

    1993-12-01

    This research program is directed at extending fundamental knowledge of atoms and molecules including their electronic structure, mutual interaction, collision dynamics, and interaction with radiation. The approach combines the use of ab initio methods--Hartree-Fock (HF) multiconfiguration HF, configuration interaction, and the recently developed quantum Monte Carlo (MC)--to describe electronic structure, intermolecular interactions, and other properties, with various methods of characterizing inelastic and reaction collision processes, and photodissociation dynamics. Present activity is focused on the development and application of the QMC method, surface catalyzed reactions, and reorientation cross sections.

  9. Plasma interactions with large spacecraft

    NASA Technical Reports Server (NTRS)

    Sagalyn, Rita C.; Maynard, Nelson C.

    1986-01-01

    Space is playing a rapidly expanding role in the conduct of the Air Force mission. Larger, more complex, high-power space platforms are planned and military astronauts will provide a new capability in spacecraft servicing. Interactions of operational satellites with the environment have been shown to degrade space sensors and electronics and to constrain systems operations. The environmental interaction effects grow nonlinearly with increasing size and power. Quantification of the interactions and development of mitigation techniques for systems-limiting interactions is essential to the success of future Air Force space operations.

  10. Imaging van der Waals Interactions.

    PubMed

    Han, Zhumin; Wei, Xinyuan; Xu, Chen; Chiang, Chi-Lun; Zhang, Yanxing; Wu, Ruqian; Ho, W

    2016-12-15

    The van der Waals interactions are responsible for a large diversity of structures and functions in chemistry, biology, and materials. Discussion of van der Waals interactions has focused on the attractive potential energy that varies as the inverse power of the distance between the two interacting partners. The origin of the attractive force is widely discussed as being due to the correlated fluctuations of electron charges that lead to instantaneous dipole-induced dipole attractions. Here, we use the inelastic tunneling probe to image the potential energy surface associated with the van der Waals interactions of xenon atoms.

  11. Interactive TV on parliament session

    NASA Astrophysics Data System (ADS)

    Royer, J.; Nguyen, H.; Martinot, O.; Preda, M.; Preteux, F.; Zaharia, T.

    2007-09-01

    This paper introduces a new interactive mobile TV application related to parliament session. This application aims to provide additional information to mobile TV users by inserting automatically and in real-time interactive contents (complementary information, subject of the current session...) into original TV program, using MPEG-4 streaming video and extra real time information (news, events, databases... from RSS streams, Internet links...). Here, we propose an architecture based on plug-in multimedia analyzers to generate the contextual description of the media and on an interactive scene generator to dynamically create related interactive scenes. Description is implemented according to the MPEG-7 standard.

  12. [Antibiotics: drug and food interactions].

    PubMed

    Hodel, M; Genné, D

    2009-10-07

    Antibiotics are widely prescribed in medical practice. Many of them induce or are subject to interactions that may diminish their anti-infectious efficiency or elicit toxic effects. Food intake can influence the effectiveness of an antibiotic. Certain antibiotics can lower the effectiveness of oral contraception. Oral anticoagulation can be influenced to a great extent by antibiotics and controls are necessary. Interactions are also possible via enzymatic induction or inhibition of cytochromes. The use of an interaction list with substrates of cytochromes enables to anticipate. Every new prescription should consider a possible drug or food interaction.

  13. Structural interaction with control systems

    NASA Technical Reports Server (NTRS)

    Noll, R. B.; Zvara, J.

    1971-01-01

    A monograph which assesses the state of the art of space vehicle design and development is presented. The monograph presents criteria and recommended practices for determining the structural data and a mathematical structural model of the vehicle needed for accurate prediction of structure and control-system interaction; for design to minimize undesirable interactions between the structure and the control system; and for determining techniques to achieve the maximum desirable interactions and associated structural design benefits. All space vehicles are treated, including launch vehicles, spacecraft, and entry vehicles. Important structural characteristics which affect the structural model used for structural and control-system interaction analysis are given.

  14. RKKY interaction in bilayer graphene

    NASA Astrophysics Data System (ADS)

    Mohammadi, Yawar; Moradian, Rostam

    2015-12-01

    We study the RKKY interaction between two magnetic impurities located on the same layer (intralayer case) or on different layers (interlayer case) in undoped bilayer graphene (BLG) in the four-bands model, by directly calculating the Green functions in the eigenvalues and eigenvectors representation. Our results show that both intra- and interlayer RKKY interactions between two magnetic impurities located on the same (opposite) sublattice are always ferromagnetic (antiferromagnetic). Furthermore we find unusual long-distance decay of the RKKY interaction in BLG. The intralyer RKKY interactions between two magnetic impurities located on the same sublattice, J AnAn(R) and J BnBn(R), decay closely as 1 /R6 and 1 /R2 at large impurity distances respectively, but when they are located on opposite sublattices the RKKY interactions exhibit 1 /R4 decays approximately. In the interlayer case, the RKKY interactions between two magnetic impurities located on the same sublattice show a decay close to 1 /R4 at large impurity distances, but if two magnetic impurities be on opposite sublattices the RKKY interactions, J A1B2(R) and J B1A2(R), decay closely as 1 /R6 and 1 /R2 respectively. Both intra- and interlayer RKKY interactions have anisotropic oscillatory factors which for intralayer case is equal to that for single layer graphene (SLG). Our results at weak and strong interlayer coupling limits reduce to the RKKY interaction of SLG and that of BLG in the two-bands approximation respectively.

  15. Self-interacting dark matter

    SciTech Connect

    Tulin, Sean

    2014-06-24

    The particle physics nature of dark matter (DM) can leave an imprint on the structure of Universe. If DM has a sizable cross section for self-interactions (much larger than the typical weak scale cross section), this can affect the density profiles of DM halos. Moreover, there exist long-standing discrepancies on small scales between astrophysical observations and predictions from N-body simulations of collisionless DM, which suggests that DM may be self-interacting. Here, we review these discrepancies, we discuss the particle physics implications of self-interacting DM, and we show that DM self-interactions have interesting implications for direct and indirect detection searches.

  16. Josef Alber's "Interaction of Color": From Print to Interactive Multimedia.

    ERIC Educational Resources Information Center

    Whiteley, Jerry; Roberts, Joseph

    1990-01-01

    Describes the development of interactive, multimedia courseware based on Josef Alber's book, "Interaction of Color." Alber's ideas and teachings on the perceptions of color are explained, and steps involving computer graphics, hardware, and software that resulted in the use of CD-ROM and videodisc with an Apple Macintosh II are detailed.…

  17. Why Interactivity Works: Interactive Priming of Mental Rotation

    ERIC Educational Resources Information Center

    Smith, Glenn Gordon; Olkun, Sinan

    2005-01-01

    This study has important implications for microworlds such as Logo, HyperGami, and Newton's World, which use interaction to learn spatial mental models for science, math, geometry, etc. This study tested the hypothesis that interactively rotating (dragging) virtual shapes primes mental rotation. The independent variable was observation vs.…

  18. Interactions among the Imagination, Expertise Reversal, and Element Interactivity Effects

    ERIC Educational Resources Information Center

    Leahy, Wayne; Sweller, John

    2005-01-01

    Interactions among the imagination, expertise reversal, and element interactivity effects were investigated in 2 experiments. In Experiment 1, less knowledgeable primary school students learning to use a bus timetable produced better performance under study than imagination conditions, but an increase in their experience reversed the result,…

  19. The n→π* Interaction

    PubMed Central

    2017-01-01

    Conspectus The carbonyl group holds a prominent position in chemistry and biology not only because it allows diverse transformations but also because it supports key intermolecular interactions, including hydrogen bonding. More recently, carbonyl groups have been found to interact with a variety of nucleophiles, including other carbonyl groups, in what we have termed an n→π* interaction. In an n→π* interaction, a nucleophile donates lone-pair (n) electron density into the empty π* orbital of a nearby carbonyl group. Mixing of these orbitals releases energy, resulting in an attractive interaction. Hints of such interactions were evident in small-molecule crystal structures as early as the 1970s, but not until 2001 was the role of such interactions articulated clearly. These non-covalent interactions were first discovered during investigations into the thermostability of the proline-rich protein collagen, which achieves a robust structure despite a relatively low potential for hydrogen bonding. It was found that by modulating the distance between two carbonyl groups in the peptide backbone, one could alter the conformational preferences of a peptide bond to proline. Specifically, only the trans conformation of a peptide bond to proline allows for an attractive interaction with an adjacent carbonyl group, so when one increases the proximity of the two carbonyl groups, one enhances their interaction and promotes the trans conformation of the peptide bond, which increases the thermostability of collagen. More recently, attention has been paid to the nature of these interactions. Some have argued that rather than resulting from electron donation, carbonyl interactions are a particular example of dipolar interactions that are well-approximated by classical mechanics. However, experimental evidence has demonstrated otherwise. Numerous examples now exist where an increase in the dipole moment of a carbonyl group decreases the strength of its interactions with other

  20. The n→π* Interaction.

    PubMed

    Newberry, Robert W; Raines, Ronald T

    2017-08-15

    The carbonyl group holds a prominent position in chemistry and biology not only because it allows diverse transformations but also because it supports key intermolecular interactions, including hydrogen bonding. More recently, carbonyl groups have been found to interact with a variety of nucleophiles, including other carbonyl groups, in what we have termed an n→π* interaction. In an n→π* interaction, a nucleophile donates lone-pair (n) electron density into the empty π* orbital of a nearby carbonyl group. Mixing of these orbitals releases energy, resulting in an attractive interaction. Hints of such interactions were evident in small-molecule crystal structures as early as the 1970s, but not until 2001 was the role of such interactions articulated clearly. These non-covalent interactions were first discovered during investigations into the thermostability of the proline-rich protein collagen, which achieves a robust structure despite a relatively low potential for hydrogen bonding. It was found that by modulating the distance between two carbonyl groups in the peptide backbone, one could alter the conformational preferences of a peptide bond to proline. Specifically, only the trans conformation of a peptide bond to proline allows for an attractive interaction with an adjacent carbonyl group, so when one increases the proximity of the two carbonyl groups, one enhances their interaction and promotes the trans conformation of the peptide bond, which increases the thermostability of collagen. More recently, attention has been paid to the nature of these interactions. Some have argued that rather than resulting from electron donation, carbonyl interactions are a particular example of dipolar interactions that are well-approximated by classical mechanics. However, experimental evidence has demonstrated otherwise. Numerous examples now exist where an increase in the dipole moment of a carbonyl group decreases the strength of its interactions with other carbonyl

  1. The Cation-π Interaction

    PubMed Central

    DOUGHERTY, DENNIS A.

    2014-01-01

    CONSPECTUS The chemistry community now recognizes the cation-π interaction as a major force for molecular recognition, joining the hydrophobic effect, the hydrogen bond, and the ion pair in determining macromolecular structure and drug-receptor interactions. This Account provides the author’s perspective on the intellectual origins and fundamental nature of the cation-π interaction. Early studies on cyclophanes established that water-soluble, cationic molecules would forgo aqueous solvation to enter a hydrophobic cavity if that cavity was lined with π systems. Important gas phase studies established the fundamental nature of the cation-π interaction. The strength of the cation-π interaction – Li+ binds to benzene with 38 kcal/mol of binding energy; NH4+ with 19 kcal/mol– distinguishes it from the weaker polar-π interactions observed in the benzene dimer or water-benzene complexes. In addition to the substantial intrinsic strength of the cation-π interaction in gas phase studies, the cation-π interaction remains energetically significant in aqueous media and under biological conditions. Many studies have shown that cation-π interactions can enhance binding energies by 2 – 5 kcal/mol, making them competitive with hydrogen bonds and ion pairs in drug-receptor and protein-protein interactions. As with other noncovalent interactions involving aromatic systems, the cation-π interaction includes a substantial electrostatic component. The six (four) Cδ−–Hδ+ bond dipoles of a molecule like benzene (ethylene) combine to produce a region of negative electrostatic potential on the face of the π system. Simple electrostatics facilitate a natural attraction of cations to the surface. The trend for (gas phase) binding energies is Li+>Na+>K+>Rb+: as the ion gets larger the charge is dispersed over a larger sphere and binding interactions weaken, a classical electrostatic effect. On other hand, polarizability does not define these interactions. Cyclohexane

  2. Interact - Access to the Arctic

    NASA Astrophysics Data System (ADS)

    Johansson, M.; Callaghan, T. V.

    2013-12-01

    INTERACT is currently a network of 50 terrestrial research stations from all Arctic countries, but is still growing. The network was inaugurated in January 2011 when it received an EU 7th Framework award. INTERACT's main objective is to build capacity for identifying, understanding, predicting and responding to diverse environmental changes throughout the wide environmental and land-use envelopes of the Arctic. Implicit in this objective is the task to build capacity for monitoring, research, education and outreach. INTERACT is increasing access to the Arctic: 20 INTERACT research stations in Europe and Russia are offering Transnational Access and so far, 5600 person-days of access have been granted from the total of 10,000 offered. An INTERACT Station Managers' Forum facilitates a dialogue among station managers on subjects such as best practice in station management and standardised monitoring. The Station Managers' Forum has produced a unique 'one-stop-shop' for information from 45 research stations in an informative and attractive Station Catalogue that is available in hard copy and on the INTERACT web site (www.eu-interact.org). INTERACT also includes three joint research activities that are improving monitoring in remote, harsh environments and are making data capture and dissemination more efficient. Already, new equipment for measuring feedbacks from the land surface to the climate system has been installed at several locations, while best practices for sensor networking have been established. INTERACT networks with most of the high-level Arctic organisations: it includes AMAP and WWF as partners, is endorsed by IASC and CBMP, has signed MoUs with ISAC and the University of the Arctic, is a task within SAON, and contributes to the Cold Region community within GEO/GEOSS. INTERACT welcomes other interactions.

  3. Strong interactions in air showers

    SciTech Connect

    Dietrich, Dennis D.

    2015-03-02

    We study the role new gauge interactions in extensions of the standard model play in air showers initiated by ultrahigh-energy cosmic rays. Hadron-hadron events remain dominated by quantum chromodynamics, while projectiles and/or targets from beyond the standard model permit us to see qualitative differences arising due to the new interactions.

  4. Distinguishing Ordinal and Disordinal Interactions

    ERIC Educational Resources Information Center

    Widaman, Keith F.; Helm, Jonathan L.; Castro-Schilo, Laura; Pluess, Michael; Stallings, Michael C.; Belsky, Jay

    2012-01-01

    Re-parameterized regression models may enable tests of crucial theoretical predictions involving interactive effects of predictors that cannot be tested directly using standard approaches. First, we present a re-parameterized regression model for the Linear x Linear interaction of 2 quantitative predictors that yields point and interval estimates…

  5. Transformations: Mobile Interaction & Language Learning

    ERIC Educational Resources Information Center

    Carroll, Fiona; Kop, Rita; Thomas, Nathan; Dunning, Rebecca

    2015-01-01

    Mobile devices and the interactions that these technologies afford have the potential to change the face and nature of education in our schools. Indeed, mobile technological advances are seen to offer better access to educational material and new interactive ways to learn. However, the question arises, as to whether these new technologies are…

  6. Designing Interactive Online Nursing Courses

    ERIC Educational Resources Information Center

    Jain, Smita; Jain, Pawan

    2015-01-01

    This study empirically tests the relation between the instructional design elements and the overall meaningful interactions among online students. Eighteen online graduate nursing courses are analyzed using bivariate and multivariate analysis techniques. Findings suggest that the quantity of meaningful interaction among learners can be improved by…

  7. Some Aspects of Classroom Interaction.

    ERIC Educational Resources Information Center

    Sjorslev, Sten

    A model for analyzing classroom interaction is presented. The model focuses on two issues: management of turn-taking and the relationship between ways of interacting and outcome of the teaching/learning process. Turn-taking is seen as one element of conversational style, in which speakers signal degree of involvement by using different linguistic…

  8. The Power of Interactive Whiteboards.

    ERIC Educational Resources Information Center

    Ekhaml, Leticia

    2002-01-01

    Describes the use of interactive whiteboards, a new type of instructional presentation technology that allows users to control computer applications from the board. Highlights include vendors; multimedia online instruction; rear-projection models; examples of classroom uses; contests and opportunities for schools to obtain interactive whiteboards;…

  9. Distinguishing Ordinal and Disordinal Interactions

    ERIC Educational Resources Information Center

    Widaman, Keith F.; Helm, Jonathan L.; Castro-Schilo, Laura; Pluess, Michael; Stallings, Michael C.; Belsky, Jay

    2012-01-01

    Re-parameterized regression models may enable tests of crucial theoretical predictions involving interactive effects of predictors that cannot be tested directly using standard approaches. First, we present a re-parameterized regression model for the Linear x Linear interaction of 2 quantitative predictors that yields point and interval estimates…

  10. Interactions between diatoms and bacteria.

    PubMed

    Amin, Shady A; Parker, Micaela S; Armbrust, E Virginia

    2012-09-01

    Diatoms and bacteria have cooccurred in common habitats for hundreds of millions of years, thus fostering specific associations and interactions with global biogeochemical consequences. Diatoms are responsible for one-fifth of the photosynthesis on Earth, while bacteria remineralize a large portion of this fixed carbon in the oceans. Through their coexistence, diatoms and bacteria cycle nutrients between oxidized and reduced states, impacting bioavailability and ultimately feeding higher trophic levels. Here we present an overview of how diatoms and bacteria interact and the implications of these interactions. We emphasize that heterotrophic bacteria in the oceans that are consistently associated with diatoms are confined to two phyla. These consistent bacterial associations result from encounter mechanisms that occur within a microscale environment surrounding a diatom cell. We review signaling mechanisms that occur in this microenvironment to pave the way for specific interactions. Finally, we discuss known interactions between diatoms and bacteria and exciting new directions and research opportunities in this field. Throughout the review, we emphasize new technological advances that will help in the discovery of new interactions. Deciphering the languages of diatoms and bacteria and how they interact will inform our understanding of the role these organisms have in shaping the ocean and how these interactions may change in future oceans.

  11. Mental Models in Social Interaction

    ERIC Educational Resources Information Center

    Fernandez-Berrocal, Pablo; Santamaria, Carlos

    2006-01-01

    In this study, the authors introduce a new way to analyze cognitive change during social interactions, based on the mental model theory of reasoning. From this approach, cognitive performance can be improved for solving problems that require multiple models when participants in a social interaction group maintain qualitatively different models of…

  12. Drug interactions with herbal medicines.

    PubMed

    Shi, Shaojun; Klotz, Ulrich

    2012-02-01

    In recent years, the issue of herbal medicine-drug interactions has generated significant concern. Such interactions can increase the risk for an individual patient, especially with regard to drugs with a narrow therapeutic index (e.g. warfarin, ciclosporin and digoxin). The present article summarizes herbal medicine-drug interactions involving mainly inhibition or induction of cytochrome P450 enzymes and/or drug transporters. An increasing number of in vitro and animal studies, case reports and clinical trials evaluating such interactions have been reported, and the majority of the interactions may be difficult to predict. Potential pharmacodynamic and/or pharmacokinetic interactions of commonly used herbal medicines (black cohosh, garlic, Ginkgo, goldenseal, kava, milk thistle, Panax ginseng, Panax quinquefolius, saw palmetto and St John's wort) with conventional drugs are presented, and sometimes the results are contradictory. Clinical implications of herbal medicine-drug interactions depend on a variety of factors, such as the co-administered drugs, the patient characteristics, the origin of the herbal medicines, the composition of their constituents and the applied dosage regimens. To optimize the use of herbal medicines, further controlled studies are urgently needed to explore their potential for interactions with conventional drugs and to delineate the underlying mechanisms.

  13. Results-Based Interaction Design

    ERIC Educational Resources Information Center

    Weiss, Meredith

    2008-01-01

    Interaction design is a user-centered approach to development in which users and their goals are the driving force behind a project's design. Interaction design principles are fundamental to the design and implementation of effective websites, but they are not sufficient. This article argues that, to reach its full potential, a website should also…

  14. Interactive Cultural Cultivating in FLT

    ERIC Educational Resources Information Center

    Yang, Youwen

    2010-01-01

    Culture cultivating in foreign language teaching (FLT) is usually conducted through factual introductions in the form of articles, books, seminars, lectures or workshops. This approach regards L2 learners as passive receivers of cultural knowledge without their interaction involved. This paper aims at raising an interactive approach to develop L2…

  15. The Power of Interactive Whiteboards.

    ERIC Educational Resources Information Center

    Ekhaml, Leticia

    2002-01-01

    Describes the use of interactive whiteboards, a new type of instructional presentation technology that allows users to control computer applications from the board. Highlights include vendors; multimedia online instruction; rear-projection models; examples of classroom uses; contests and opportunities for schools to obtain interactive whiteboards;…

  16. Interactive Flow in Exercise Pedagogy

    ERIC Educational Resources Information Center

    Lloyd, Rebecca; Smith, Stephen

    2006-01-01

    A phenomenology of the bodily experience of interactive flow adds to Csikszentmihalyi's flow theory. Whereas Csikszentmihalyi attended to teachers' and students' experiences of flow separately, this inquiry explores flow through three water-inspired layers of physical interaction between fitness professionals and their clients. Teaching fitness is…

  17. Interactive Flow in Exercise Pedagogy

    ERIC Educational Resources Information Center

    Lloyd, Rebecca; Smith, Stephen

    2006-01-01

    A phenomenology of the bodily experience of interactive flow adds to Csikszentmihalyi's flow theory. Whereas Csikszentmihalyi attended to teachers' and students' experiences of flow separately, this inquiry explores flow through three water-inspired layers of physical interaction between fitness professionals and their clients. Teaching fitness is…

  18. Gaming Redefines Interactivity for Learning

    ERIC Educational Resources Information Center

    DeKanter, Nick

    2005-01-01

    The new definition of interactivity has as its focal point the skills of people, not the capabilities of the technology. The goal is to enhance the interaction between people and the learning that can only occur among curious and motivated individuals working together. The social nature of people, the increasing capabilities of technology and the…

  19. The Wonders of Interactive Whiteboards

    ERIC Educational Resources Information Center

    Starkman, Neal

    2006-01-01

    This article discusses the advantages of using interactive whiteboards in the classroom. Developed by Smart Technologies, the Smart Board is one of several interactive whiteboards on the market today. Through Smart Board, starters can write, erase, and perform mouse functions with their finger, a pen, or anything with a maneuverable, firm surface.…

  20. Speculations on Design Team Interactions.

    ERIC Educational Resources Information Center

    Hedberg, John; Sims, Rod

    2001-01-01

    Discussion of the design of effective learning environments focuses on design team interactions. Topics include designer intention and instructor implementation; technology tools and their use; instructional design processes, including computer interfaces and interaction possibilities; learner as actor; multimedia; and interpersonal communication.…

  1. Assessing Preference for Social Interactions

    ERIC Educational Resources Information Center

    Clay, Casey J.; Samaha, Andrew L.; Bloom, Sarah E.; Bogoev, Bistra K.; Boyle, Megan A.

    2013-01-01

    We examined a procedure to assess preference for social interactions in individuals with intellectual and developmental disabilities. Preferences were identified in five individuals using a paired-choice procedure in which participants approached therapists who provided different forms of social interactions. A subsequent tracking test showed that…

  2. Gaming Redefines Interactivity for Learning

    ERIC Educational Resources Information Center

    DeKanter, Nick

    2005-01-01

    The new definition of interactivity has as its focal point the skills of people, not the capabilities of the technology. The goal is to enhance the interaction between people and the learning that can only occur among curious and motivated individuals working together. The social nature of people, the increasing capabilities of technology and the…

  3. Environmental Interactions Working Group Report

    NASA Technical Reports Server (NTRS)

    Stevens, N. J.; Wiskerchen, M.

    1984-01-01

    Interactions between spacecraft systems and the space charged particle environment are reviewed and recommendations are presented for both near-term and far-term research considerations. Transient environment models, large space structures, solar and nuclear power systems/environment interactions, single event upsets, material degradation, and planetary missions are addressed.

  4. Perceived Attractiveness and Classroom Interactions

    ERIC Educational Resources Information Center

    Algozzine, Bob

    1977-01-01

    Adams and Cohen (1974) demonstrated that facial attractiveness was a salient factor in differential student-teacher interactions. This research investigates further the interaction between teachers and children perceived to be attractive or unattractive by those teachers. It was hypothesized that attractive children would exhibit more "positive,"…

  5. The Wonders of Interactive Whiteboards

    ERIC Educational Resources Information Center

    Starkman, Neal

    2006-01-01

    This article discusses the advantages of using interactive whiteboards in the classroom. Developed by Smart Technologies, the Smart Board is one of several interactive whiteboards on the market today. Through Smart Board, starters can write, erase, and perform mouse functions with their finger, a pen, or anything with a maneuverable, firm surface.…

  6. Interactions between Diatoms and Bacteria

    PubMed Central

    Amin, Shady A.; Parker, Micaela S.

    2012-01-01

    Summary: Diatoms and bacteria have cooccurred in common habitats for hundreds of millions of years, thus fostering specific associations and interactions with global biogeochemical consequences. Diatoms are responsible for one-fifth of the photosynthesis on Earth, while bacteria remineralize a large portion of this fixed carbon in the oceans. Through their coexistence, diatoms and bacteria cycle nutrients between oxidized and reduced states, impacting bioavailability and ultimately feeding higher trophic levels. Here we present an overview of how diatoms and bacteria interact and the implications of these interactions. We emphasize that heterotrophic bacteria in the oceans that are consistently associated with diatoms are confined to two phyla. These consistent bacterial associations result from encounter mechanisms that occur within a microscale environment surrounding a diatom cell. We review signaling mechanisms that occur in this microenvironment to pave the way for specific interactions. Finally, we discuss known interactions between diatoms and bacteria and exciting new directions and research opportunities in this field. Throughout the review, we emphasize new technological advances that will help in the discovery of new interactions. Deciphering the languages of diatoms and bacteria and how they interact will inform our understanding of the role these organisms have in shaping the ocean and how these interactions may change in future oceans. PMID:22933565

  7. Results-Based Interaction Design

    ERIC Educational Resources Information Center

    Weiss, Meredith

    2008-01-01

    Interaction design is a user-centered approach to development in which users and their goals are the driving force behind a project's design. Interaction design principles are fundamental to the design and implementation of effective websites, but they are not sufficient. This article argues that, to reach its full potential, a website should also…

  8. Designing Interactive Online Nursing Courses

    ERIC Educational Resources Information Center

    Jain, Smita; Jain, Pawan

    2015-01-01

    This study empirically tests the relation between the instructional design elements and the overall meaningful interactions among online students. Eighteen online graduate nursing courses are analyzed using bivariate and multivariate analysis techniques. Findings suggest that the quantity of meaningful interaction among learners can be improved by…

  9. Emotional intelligence and social interaction.

    PubMed

    Lopes, Paulo N; Brackett, Marc A; Nezlek, John B; Schütz, Astrid; Sellin, Ina; Salovey, Peter

    2004-08-01

    Two studies found positive relationships between the ability to manage emotions and the quality of social interactions, supporting the predictive and incremental validity of an ability measure of emotional intelligence, the Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT). In a sample of 118 American college students (Study 1), higher scores on the managing emotions subscale of the MSCEIT were positively related to the quality of interactions with friends, evaluated separately by participants and two friends. In a diary study of social interaction with 103 German college students (Study 2), managing emotions scores were positively related to the perceived quality of interactions with opposite sex individuals. Scores on this subscale were also positively related to perceived success in impression management in social interactions with individuals of the opposite sex. In both studies, the main findings remained statistically significant after controlling for Big Five personality traits.

  10. Inferring biotic interactions from proxies.

    PubMed

    Morales-Castilla, Ignacio; Matias, Miguel G; Gravel, Dominique; Araújo, Miguel B

    2015-06-01

    Inferring biotic interactions from functional, phylogenetic and geographical proxies remains one great challenge in ecology. We propose a conceptual framework to infer the backbone of biotic interaction networks within regional species pools. First, interacting groups are identified to order links and remove forbidden interactions between species. Second, additional links are removed by examination of the geographical context in which species co-occur. Third, hypotheses are proposed to establish interaction probabilities between species. We illustrate the framework using published food-webs in terrestrial and marine systems. We conclude that preliminary descriptions of the web of life can be made by careful integration of data with theory. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Electrostatic interactions in molecular materials

    NASA Astrophysics Data System (ADS)

    Painelli, Anna; Terenziani, Francesca

    2004-03-01

    Non-additive collective behavior appears in molecular materials as a result of intermolecular interactions. We present a model for interacting polar and polarizable molecules that applies to different supramolecular architectures of donor-π-acceptor molecules. We follow a bottom-up modeling strategy: the detailed analysis of spectroscopic data of solvated molecules leads to the definition of a simple two-state model for the molecular units. Classical electrostatic interactions are then introduced to model molecular clusters. The molecular properties are strickingly affected by supramolecular interactions, as demonstrated by spectroscopic studies. Brand new phenomena, like phase transitions and multielectron transfer, with no counterpart at the molecular level are observed as direct consequences of electrostatic intermolecular interactions.

  12. Scattering calculations and confining interactions

    NASA Technical Reports Server (NTRS)

    Buck, Warren W.; Maung, Khin M.

    1993-01-01

    Most of the research work performed under this grant were concerned with strong interaction processes ranging from kaon-nucleon interaction to proton-nucleus scattering calculations. Research performed under this grant can be categorized into three groups: (1) parametrization of fundamental interactions, (2) development of formal theory, and (3) calculations based upon the first two. Parametrizations of certain fundamental interactions, such as kaon-nucleon interaction, for example, were necessary because kaon-nucleon scattering amplitude was needed to perform kaon-nucleus scattering calculations. It was possible to calculate kaon-nucleon amplitudes from the first principle, but it was unnecessary for the purpose of the project. Similar work was also done for example for anti-protons and anti-nuclei. Formal developments to some extent were also pursued so that consistent calculations can be done.

  13. Hyperfine interaction in hydrogenated graphene

    NASA Astrophysics Data System (ADS)

    Garcia, Noel; Melle, Manuel; Fernandez-Rossier, Joaquin

    We study the hyperfine interaction of Hydrogen chemisorbed in graphene nanostructures with a gap in their spectrum, such as islands and ribbons. Chemisorption of Hydrogen on graphene results in a bound in-gap state that hosts a single electron localized around the adatom. Using both density functional theory and a four-orbital tight-binding model we study the hyperfine interaction between the hydrogen nuclear spin and the conduction electrons in graphene. We find that the strength of the hyperfine interaction decreases for larger nanostructures for which the energy gap is smaller. We then compare the results of the hyperfine interaction for large nanostructures with those of graphene 2D crystal with a periodic arrangement of chemisorbed Hydrogen atoms, obtaining very similar results. The magnitude of the hyperfine interaction is about 150 MHz, in line with that of Si:P. We acknowledge financial support by Marie-Curie-ITN 607904-SPINOGRAPH.

  14. Drug Interactions in Childhood Cancer

    PubMed Central

    Haidar, Cyrine; Jeha, Sima

    2016-01-01

    Children with cancer are increasingly benefiting from novel therapeutic strategies and advances in supportive care, as reflected in improvements in both their survival and quality of life. However, the continuous emergence of new oncology drugs and supportive care agents has also increased the possibility of deleterious drug interactions and healthcare providers need to practice extreme caution when combining medications. In this review, we discuss the most common interactions of chemotherapeutic agents with supportive care drugs such as anticonvulsants, antiemetics, uric acid–lowering agents, acid suppressants, antimicrobials, and pain management medications in pediatric oncology patients. As chemotherapy agents interact not only with medications but also with foods and herbal supplements that patients receive during the course of their treatment, we also briefly review such interactions and provide recommendations to avoid unwanted and potentially fatal interactions in children with cancer. PMID:20869315

  15. Final State Interactions Effects in Neutrino-Nucleus Interactions

    SciTech Connect

    Golan, Tomasz; Juszczak, Cezary; Sobczyk, Jan T.

    2012-07-01

    Final State Interactions effects are discussed in the context of Monte Carlo simulations of neutrino-nucleus interactions. A role of Formation Time is explained and several models describing this effect are compared. Various observables which are sensitive to FSI effects are reviewed including pion-nucleus interaction and hadron yields in backward hemisphere. NuWro Monte Carlo neutrino event generator is described and its ability to understand neutral current $\\pi^0$ production data in $\\sim 1$ GeV neutrino flux experiments is demonstrated.

  16. Interactive computations: toward risk management in interactive intelligent systems.

    PubMed

    Skowron, Andrzej; Jankowski, Andrzej

    Understanding the nature of interactions is regarded as one of the biggest challenges in projects related to complex adaptive systems. We discuss foundations for interactive computations in interactive intelligent systems (IIS), developed in the Wistech program and used for modeling complex systems. We emphasize the key role of risk management in problem solving by IIS. The considerations are based on experience gained in real-life projects concerning, e.g., medical diagnosis and therapy support, control of an unmanned helicopter, fraud detection algorithmic trading or fire commander decision support.

  17. Interactive computer code for dynamic and soil structure interaction analysis

    SciTech Connect

    Mulliken, J.S.

    1995-12-01

    A new interactive computer code is presented in this paper for dynamic and soil-structure interaction (SSI) analyses. The computer program FETA (Finite Element Transient Analysis) is a self contained interactive graphics environment for IBM-PC`s that is used for the development of structural and soil models as well as post-processing dynamic analysis output. Full 3-D isometric views of the soil-structure system, animation of displacements, frequency and time domain responses at nodes, and response spectra are all graphically available simply by pointing and clicking with a mouse. FETA`s finite element solver performs 2-D and 3-D frequency and time domain soil-structure interaction analyses. The solver can be directly accessed from the graphical interface on a PC, or run on a number of other computer platforms.

  18. Calculation of Rydberg interaction potentials

    NASA Astrophysics Data System (ADS)

    Weber, Sebastian; Tresp, Christoph; Menke, Henri; Urvoy, Alban; Firstenberg, Ofer; Büchler, Hans Peter; Hofferberth, Sebastian

    2017-07-01

    The strong interaction between individual Rydberg atoms provides a powerful tool exploited in an ever-growing range of applications in quantum information science, quantum simulation and ultracold chemistry. One hallmark of the Rydberg interaction is that both its strength and angular dependence can be fine-tuned with great flexibility by choosing appropriate Rydberg states and applying external electric and magnetic fields. More and more experiments are probing this interaction at short atomic distances or with such high precision that perturbative calculations as well as restrictions to the leading dipole-dipole interaction term are no longer sufficient. In this tutorial, we review all relevant aspects of the full calculation of Rydberg interaction potentials. We discuss the derivation of the interaction Hamiltonian from the electrostatic multipole expansion, numerical and analytical methods for calculating the required electric multipole moments and the inclusion of electromagnetic fields with arbitrary direction. We focus specifically on symmetry arguments and selection rules, which greatly reduce the size of the Hamiltonian matrix, enabling the direct diagonalization of the Hamiltonian up to higher multipole orders on a desktop computer. Finally, we present example calculations showing the relevance of the full interaction calculation to current experiments. Our software for calculating Rydberg potentials including all features discussed in this tutorial is available as open source.

  19. Additive interaction between heterogeneous environmental ...

    EPA Pesticide Factsheets

    BACKGROUND Environmental exposures often occur in tandem; however, epidemiological research often focuses on singular exposures. Statistical interactions among broad, well-characterized environmental domains have not yet been evaluated in association with health. We address this gap by conducting a county-level cross-sectional analysis of interactions between Environmental Quality Index (EQI) domain indices on preterm birth in the Unites States from 2000-2005.METHODS: The EQI, a county-level index constructed for the 2000-2005 time period, was constructed from five domain-specific indices (air, water, land, built and sociodemographic) using principal component analyses. County-level preterm birth rates (n=3141) were estimated using live births from the National Center for Health Statistics. Linear regression was used to estimate prevalence differences (PD) and 95% confidence intervals (CI) comparing worse environmental quality to the better quality for each model for a) each individual domain main effect b) the interaction contrast and c) the two main effects plus interaction effect (i.e. the “net effect”) to show departure from additive interaction for the all U.S counties. Analyses were also performed for subgroupings by four urban/rural strata. RESULTS: We found the suggestion of antagonistic interactions but no synergism, along with several purely additive (i.e., no interaction) associations. In the non-stratified model, we observed antagonistic interac

  20. Additive interaction between heterogeneous environmental ...

    EPA Pesticide Factsheets

    BACKGROUND Environmental exposures often occur in tandem; however, epidemiological research often focuses on singular exposures. Statistical interactions among broad, well-characterized environmental domains have not yet been evaluated in association with health. We address this gap by conducting a county-level cross-sectional analysis of interactions between Environmental Quality Index (EQI) domain indices on preterm birth in the Unites States from 2000-2005.METHODS: The EQI, a county-level index constructed for the 2000-2005 time period, was constructed from five domain-specific indices (air, water, land, built and sociodemographic) using principal component analyses. County-level preterm birth rates (n=3141) were estimated using live births from the National Center for Health Statistics. Linear regression was used to estimate prevalence differences (PD) and 95% confidence intervals (CI) comparing worse environmental quality to the better quality for each model for a) each individual domain main effect b) the interaction contrast and c) the two main effects plus interaction effect (i.e. the “net effect”) to show departure from additive interaction for the all U.S counties. Analyses were also performed for subgroupings by four urban/rural strata. RESULTS: We found the suggestion of antagonistic interactions but no synergism, along with several purely additive (i.e., no interaction) associations. In the non-stratified model, we observed antagonistic interac

  1. Adverse food-drug interactions.

    PubMed

    de Boer, Alie; van Hunsel, Florence; Bast, Aalt

    2015-12-01

    Food supplements and herbal products are increasingly popular amongst consumers. This leads to increased risks of interactions between prescribed drugs and these products containing bioactive ingredients. From 1991 up to 2014, 55 cases of suspected adverse drug reactions due to concomitant intake of health-enhancing products and drugs were reported to Lareb, the Netherlands Pharmacovigilance Centre. An overview of these suspected interactions is presented and their potential mechanisms of action are described. Mainly during the metabolism of xenobiotics and due to the pharmacodynamics effects interactions seem to occur, which may result in adverse drug reactions. Where legislation is seen to distinct food and medicine, legislation concerning these different bioactive products is less clear-cut. This can only be resolved by increasing the molecular knowledge on bioactive substances and their potential interactions. Thereby potential interactions can be better understood and prevented on an individual level. By considering the dietary pattern and use of bioactive substances with prescribed medication, both health professionals and consumers will be increasingly aware of interactions and these interactive adverse effects can be prevented.

  2. Haldane relation for interacting dimers

    NASA Astrophysics Data System (ADS)

    Giuliani, Alessandro; Mastropietro, Vieri; Lucio Toninelli, Fabio

    2017-03-01

    We consider a model of weakly interacting close-packed dimers on the two-dimensional square lattice. In a previous paper, we computed both the multi-point dimer correlations, which display non-trivial critical exponents, continuously varying with the interaction strength; and the height fluctuations, which, after proper coarse graining and rescaling, converge to a massless Gaussian field with a suitable interaction-dependent pre-factor (‘amplitude’). In this paper, we prove the identity between the critical exponent of the two-point dimer correlation and the amplitude of this massless Gaussian field. This identity is the restatement, in the context of interacting dimers, of one of the Haldane universality relations, part of his Luttinger-liquid conjecture, originally formulated in the context of one-dimensional interacting Fermi systems. Its validity is a strong confirmation of the effective massless Gaussian field description of the interacting dimer model, which was proposed on the basis of formal bosonization arguments. We also conjecture that a certain discrete curve defined at the lattice level via the Temperley bijection converges in the scaling limit to an SLE κ process, with κ depending non-trivially on the interaction and related in a simple way to the amplitude of the limiting Gaussian field.

  3. Hidden interaction in SBO galaxies

    NASA Astrophysics Data System (ADS)

    Galletta, G.; Bettoni, D.; Oosterloo, T.; Fasano, G.

    1990-11-01

    Galaxies, like plants, show a large variety of grafts: an individual of some type connects physically with a neighborhood of same or different type. The effects of these interactions between galaxies have a broad range of morphologies depending, among other quantities, on the distance of the closest approach between systems and the relative size of the two galaxies. A sketch of the possible situations is shown in tabular form. This botanical classification is just indicative, because the effects of interactions can be notable also at relatively large separations, when additional conditions are met, as for example low density of the interacting systems or the presence of intra-cluster gas. In spite of the large variety of encounters and effects, in the literature the same terms are often used to refer to different types of interactions. Analysis indicates that only few of the situations show evident signs of interaction. They appear to be most relevant when the size of the two galaxies is comparable. Bridges and tails, like the well known case of NGC 4038/39, the Antennae, are only observed for a very low percentage of all galaxies (approx. 0.38 percent, Arp and Madore 1977). In most cases of gravitational bond between two galaxies, the effects of interactions are not relevant or evident. For instance, the detection of stellar shells (Malin and Carter 1983), which have been attributed to the accretion of gas stripped from another galaxy or to the capture and disruption of a small stellar system (Quinn 1984), requires particular observing and reduction techniques. Besides these difficulties of detection, time plays an important role in erasing, within a massive galaxy, the effects of interactions with smaller objects. This can happen on a timescale shorter than the Hubble time, so the number of systems now showing signs of interaction suggests lower limits to the true frequency of interactions in the life-time of a stellar system.

  4. Hidden interaction in SBO galaxies

    NASA Technical Reports Server (NTRS)

    Galletta, G.; Bettoni, D.; Oosterloo, T.; Fasano, G.

    1990-01-01

    Galaxies, like plants, show a large variety of grafts: an individual of some type connects physically with a neighborhood of same or different type. The effects of these interactions between galaxies have a broad range of morphologies depending, among other quantities, on the distance of the closest approach between systems and the relative size of the two galaxies. A sketch of the possible situations is shown in tabular form. This botanical classification is just indicative, because the effects of interactions can be notable also at relatively large separations, when additional conditions are met, as for example low density of the interacting systems or the presence of intra-cluster gas. In spite of the large variety of encounters and effects, in the literature the same terms are often used to refer to different types of interactions. Analysis indicates that only few of the situations show evident signs of interaction. They appear to be most relevant when the size of the two galaxies is comparable. Bridges and tails, like the well known case of NGC 4038/39, the Antennae, are only observed for a very low percentage of all galaxies (approx. 0.38 percent, Arp and Madore 1977). In most cases of gravitational bond between two galaxies, the effects of interactions are not relevant or evident. For instance, the detection of stellar shells (Malin and Carter 1983), which have been attributed to the accretion of gas stripped from another galaxy or to the capture and disruption of a small stellar system (Quinn 1984), requires particular observing and reduction techniques. Besides these difficulties of detection, time plays an important role in erasing, within a massive galaxy, the effects of interactions with smaller objects. This can happen on a timescale shorter than the Hubble time, so the number of systems now showing signs of interaction suggests lower limits to the true frequency of interactions in the life-time of a stellar system.

  5. Health implications of drug interactions.

    PubMed

    Dukes, M N

    1990-01-01

    The awareness of the digoxin-quinidine interaction in the mid-70s led to increased interest in drug interactions. Much has been published on the subject in the form of interaction reports, handbooks, lists, cards, discs etc. However, only a few interactions in the literature have clinical significance and can be remembered by thinking in terms of groups, pharmacokinetics and probabilities. It is important to realise that drugs in a given class will have similar properties. Thus, phenylbutazone, like any other nonsteroidal anti-inflammatory drug (NSAID), is likely to potentiate the effects of warfarin. A knowledge of drug pharmacokinetics is also essential; a highly protein-bound drug may displace another when they are administered together. Remembering those drugs which induce liver enzyme formation will prevent their co-administration with drugs which have a critical dose-range. If a general practitioner can remember the few drugs in clinical practice with a narrow therapeutic index, he can consult a handbook before anything else is prescribed. Some interactions will rarely be encountered in daily general practice, i.e. those associated with tuberculosis treatment or anesthetic agents. Other interactions, e.g. the interaction between antihypertensive treatment and over-the-counter medication containing phenylpropanolamine, are more common. While most drug interactions can be avoided by thinking in terms of groups, pharmacokinetics and probabilities, some learning by rote is required, e.g. the potential for heart failure with concomitant beta-blocker and nifedipine therapy. In general, a schematic approach using thinking in terms of groups, pharmacokinetics and probabilities will prevent most clinically significant drug interactions; the rest can be avoided by consulting appropriate handbooks and specialists.

  6. Predicting Drug-Target Interactions Using Drug-Drug Interactions

    PubMed Central

    Kim, Shinhyuk; Jin, Daeyong; Lee, Hyunju

    2013-01-01

    Computational methods for predicting drug-target interactions have become important in drug research because they can help to reduce the time, cost, and failure rates for developing new drugs. Recently, with the accumulation of drug-related data sets related to drug side effects and pharmacological data, it has became possible to predict potential drug-target interactions. In this study, we focus on drug-drug interactions (DDI), their adverse effects () and pharmacological information (), and investigate the relationship among chemical structures, side effects, and DDIs from several data sources. In this study, data from the STITCH database, from drugs.com, and drug-target pairs from ChEMBL and SIDER were first collected. Then, by applying two machine learning approaches, a support vector machine (SVM) and a kernel-based L1-norm regularized logistic regression (KL1LR), we showed that DDI is a promising feature in predicting drug-target interactions. Next, the accuracies of predicting drug-target interactions using DDI were compared to those obtained using the chemical structure and side effects based on the SVM and KL1LR approaches, showing that DDI was the data source contributing the most for predicting drug-target interactions. PMID:24278248

  7. Aligned interactions in cosmic rays

    SciTech Connect

    Kempa, J.

    2015-12-15

    The first clean Centauro was found in cosmic rays years many ago at Mt Chacaltaya experiment. Since that time, many people have tried to find this type of interaction, both in cosmic rays and at accelerators. But no one has found a clean cases of this type of interaction.It happened finally in the last exposure of emulsion at Mt Chacaltaya where the second clean Centauro has been found. The experimental data for both the Centauros and STRANA will be presented and discussed in this paper. We also present our comments to the intriguing question of the existence of a type of nuclear interactions at high energy with alignment.

  8. Generalized interactions supported on hypersurfaces

    NASA Astrophysics Data System (ADS)

    Exner, Pavel; Rohleder, Jonathan

    2016-04-01

    We analyze a family of singular Schrödinger operators with local singular interactions supported by a hypersurface Σ ⊂ ℝn, n ≥ 2, being the boundary of a Lipschitz domain, bounded or unbounded, not necessarily connected. At each point of Σ the interaction is characterized by four real parameters, the earlier studied case of δ- and δ'-interactions being particular cases. We discuss spectral properties of these operators and derive operator inequalities between those referring to the same hypersurface but different couplings and describe their implications for spectral properties.

  9. Monitoring lectin interactions with carbohydrates.

    PubMed

    de Bentzmann, Sophie; Varrot, Annabelle; Imberty, Anne

    2014-01-01

    Protein-carbohydrate interactions are often involved in the first step of infection and Pseudomonas aeruginosa produces several proteins that are able to bind specifically to glycan epitopes present on host epithelia. The experimental approaches for studying protein-carbohydrate interaction have been inspired, with some adaptations, from those commonly used for protein-protein or protein-ligand interactions. A range of methods are described herein for detecting lectin activity, screening for monosaccharide or oligosaccharide specificity, determining the affinity of binding together with thermodynamics and kinetics parameters, and producing crystal of lectin-carbohydrate complexes for further structural studies.

  10. Invariants of 4-wave interactions

    NASA Astrophysics Data System (ADS)

    Balk, A.; Ferapontov, E.

    1993-05-01

    We give a complete description of one-dimensional 4-wave resonance interactions in which some extra quantities (besides momentum, energy, number of quasiparticles) are conserved. In this way we obtain new consideration laws for the kinetic equations for waves. In particular, we consider waves in optical fibers, the system of four resonantly interacting wave packets, long wave interactions of annihilation-creation type, various wave systems with quadratic dispersion laws. The results can be important for various problems concerning nonlinear wave dynamics, e.g. for nonlinear optics of waveguides.

  11. Aligned interactions in cosmic rays

    NASA Astrophysics Data System (ADS)

    Kempa, J.

    2015-12-01

    The first clean Centauro was found in cosmic rays years many ago at Mt Chacaltaya experiment. Since that time, many people have tried to find this type of interaction, both in cosmic rays and at accelerators. But no one has found a clean cases of this type of interaction.It happened finally in the last exposure of emulsion at Mt Chacaltaya where the second clean Centauro has been found. The experimental data for both the Centauros and STRANA will be presented and discussed in this paper. We also present our comments to the intriguing question of the existence of a type of nuclear interactions at high energy with alignment.

  12. Coulomb interactions in particle beams

    SciTech Connect

    Jansen, G.H. )

    1990-01-01

    This book develops analytical and computer models for beams in which Coulomb interactions are important. The research into the different phenomena of Coulomb interactions in particle beams is stimulated by developments in the field of electron beam lithography for VLSI electronics. The standard theory of charged particle optics breaks down for intense beams in which interactions between particles are significant. This monograph is devoted to the theory of these intense beams, which are not only used in VLSI electronics but also in scanning electron microscopes. The theory is also applicable to focused ion beams, which are used in VLSI mask repair.

  13. Research in interactive scene analysis

    NASA Technical Reports Server (NTRS)

    Tenenbaum, J. M.; Barrow, H. G.; Weyl, S. A.

    1976-01-01

    Cooperative (man-machine) scene analysis techniques were developed whereby humans can provide a computer with guidance when completely automated processing is infeasible. An interactive approach promises significant near-term payoffs in analyzing various types of high volume satellite imagery, as well as vehicle-based imagery used in robot planetary exploration. This report summarizes the work accomplished over the duration of the project and describes in detail three major accomplishments: (1) the interactive design of texture classifiers; (2) a new approach for integrating the segmentation and interpretation phases of scene analysis; and (3) the application of interactive scene analysis techniques to cartography.

  14. Vehicle environment interactions - An overview

    NASA Technical Reports Server (NTRS)

    Raitt, W. J.

    1988-01-01

    The advent of Space Shuttle Orbital operations utilizing science and technology payloads has led to a renewal of interest of vehicle-environmental interactions in low earth orbit. The first science payload on STS-3 showed an interaction on the surface of the Orbiter which, although it had been detected earlier on unmanned spacecraft, quickened interest in the possible impact of this phenomena on future missions. Subsequent flights have yielded data on a wide variety of interaction phenomena resulting from the large size of the Orbiter and its outgassing characteristics. These drivers have given rise to modifications in the neutral gas and plasma environments of the Space Shuttle Orbiter. The physics of the interactions result in the generation of disturbed wave fields, optical emissions and particle distributions in the vicinity of the Orbiter. In this overview, the present observations, suggested interpretations and open questions will be addressed.

  15. Weak interactions and presupernova evolution

    SciTech Connect

    Aufderheide, M.B. State Univ. of New York . Dept. of Physics)

    1991-02-19

    The role of weak interactions, particularly electron capture and {beta}{sup {minus}} decay, in presupernova evolution is discussed. The present uncertainty in these rates is examined and the possibility of improving the situation is addressed. 12 refs., 4 figs.

  16. Shell Scores with Interactive Video.

    ERIC Educational Resources Information Center

    Zemke, Ron

    1991-01-01

    Documents Shell Oil's success with interactive video training (IVT) and identifies the costs involved in this long-term investment. Provides guidelines for judging the effectiveness of IVT programs. (SK)

  17. InterAction Database (IADB)

    Cancer.gov

    The InterAction Database includes demographic and prescription information for more than 500,000 patients in the northern and middle Netherlands and has been integrated with other systems to enhance data collection and analysis.

  18. Spacecraft Environmental Interactions Technology, 1983

    NASA Technical Reports Server (NTRS)

    1985-01-01

    State of the art of environment interactions dealing with low-Earth-orbit plasmas; high-voltage systems; spacecraft charging; materials effects; and direction of future programs are contained in over 50 papers.

  19. Fluctuations and interactions in microemulsions

    SciTech Connect

    Menes, R.; Safran, S.A.; Strey, R.

    1995-12-01

    We review the properties of microemulsions as described by an interfacial model which focuses upon the deformations of the surfactant monolayer separating mesoscopic water and oil domains. In some cases, the interfacial shape is well defined, resulting in a globular phase, while in others, the interface is strongly affected by thermal fluctuations, resulting in a random, sponge-like structure. In the globular phase, interactions between globules can result in phase coexistence comparable to those observed in polymeric systems. Recent experiments indicate that these interactions can result in closed-loop coexistence regions in the isothermal, concentration phase diagram. We propose a mechanism for this reentrant phase separation based on the combined effects of a shape transition and attractive interactions. Long cylindrical globules can phase separate at relatively low interglobular attractions. A transformation from elongated globules to compact spherical drops alters the balance between the entropy and the effective interglobule interactions, leading to the remixing of the globular system.

  20. Antimicrobial peptides interact with peptidoglycan

    NASA Astrophysics Data System (ADS)

    Neelay, Om P.; Peterson, Christian A.; Snavely, Mary E.; Brown, Taylor C.; TecleMariam, Ariam F.; Campbell, Jennifer A.; Blake, Allison M.; Schneider, Sydney C.; Cremeens, Matthew E.

    2017-10-01

    Traditional therapeutics are losing effectiveness as bacterial resistance increases, and antimicrobial peptides (AMPs) can serve as an alternative source for antimicrobial agents. Their mode of action is commonly hypothesized to involve pore formation in the lipid membrane, thereby leading to cell death. However, bacterial cell walls are much more complex than just the lipid membrane. A large portion of the wall is comprised of peptidoglycan, yet we did not find any report of AMP-peptidoglycan interactions. Consequently, this work evaluated AMP-peptidoglycan and AMP-phospholipid (multilamellar vesicles) interactions through tryptophan fluorescence. Given that peptidoglycan is insoluble and vesicles are large particles, we took advantage of the unique properties of Trp-fluorescence to use one technique for two very different systems. Interestingly, melittin and cecropin A interacted with peptidoglycan to a degree similar to vancomycin, a positive control. Whether these AMP-peptidoglycan interactions relate to a killing mode of action requires further study.

  1. Refining Interaction Designs through Simplicity

    NASA Astrophysics Data System (ADS)

    Muñoz, Pablo; Giner, Pau; Pelechano, Vicente

    With more and more devices in our surroundings, users increasingly-consume applications and digital services which compete for their attention. Therefore, users appreciate simplicity when they interact with them because a less intrusive interaction allows users focus on the task at hand. This work relates an approach based on the concept of simplicity. We propose an iterative interaction design process in which we include a new role. This role is only in charge of providing simplified solutions from original designs. Moreover, we put on practice our proposal in a case study in which we design an application to support mobile workflows. We relate our experience and how new ideas were produced towards the definition of refactored interactions by means of the key of Simplicity.

  2. Bibliotherapy--The Interactive Process.

    ERIC Educational Resources Information Center

    Hynes, Arleen McCarty

    1987-01-01

    Discusses the similarities between what librarians call activity bibliotherapy and psychotherapists call poetry therapy, and the need for cooperation between these professions. The interactive aspects of bibliotherapy and the need for professional training in this process are emphasized. (CLB)

  3. Interaction energy of nonidentical atoms

    NASA Astrophysics Data System (ADS)

    Berman, P. R.

    2015-04-01

    There are different results in the literature for the interaction energy of two separated nonidentical atoms in the case when one of the atoms is prepared in an excited state. Moreover, there are different ways to define this interaction energy. If the interaction energy is defined as a shift in the energy of the initial state of the combined atomic system, it is possible to carry out a time-dependent calculation that provides an unambiguous method for obtaining this shift. The time-dependent calculations lead to an interaction energy that is an oscillatory function of the interatomic separation, in contrast to the nonoscillatory behavior that is predicted using an alternative theory based on time-independent perturbation theory.

  4. Intrapersonal Communication and Imagined Interactions.

    ERIC Educational Resources Information Center

    Honeycutt, James M.; And Others

    "Imagined interactions," which refer to a cognitive process whereby individuals imagine themselves having conversations with significant others, captures a dimension of intrapersonal communication barely understood by communication researchers. To examine this multifunctional concept, a study considered the role of "imagined…

  5. Revealing Non-Covalent Interactions

    PubMed Central

    Johnson, Erin R.; Keinan, Shahar; Mori-Sánchez, Paula; Contreras-García, Julia; Cohen, Aron J.; Yang, Weitao

    2010-01-01

    Molecular structure does not easily identify the intricate non-covalent interactions that govern many areas of biology and chemistry, including design of new materials and drugs. We develop an approach to detect non-covalent interactions in real space, based on the electron density and its derivatives. Our approach reveals underlying chemistry that compliments the covalent structure. It provides a rich representation of van der Waals interactions, hydrogen bonds, and steric repulsion in small molecules, molecular complexes, and solids. Most importantly, the method, requiring only knowledge of the atomic coordinates, is efficient and applicable to large systems, such as proteins or DNA. Across these applications, a view of non-bonded interactions emerges as continuous surfaces rather than close contacts between atom pairs, offering rich insight into the design of new and improved ligands. PMID:20394428

  6. An interacting adiabatic quantum motor

    NASA Astrophysics Data System (ADS)

    Viola Kusminskiy, Silvia; Bruch, Anton; von Oppen, Felix

    We consider the effect of electron-electron interactions on the performance of an adiabatic quantum motor based on a Thouless pump operating in reverse. We model such a device by electrons in a 1d wire coupled to a slowly moving periodic potential associated with the classical mechanical degree of freedom of the motor. This periodic degree of freedom is set into motion by a bias voltage applied to the 1d electron channel. We investigate the Thouless motor with interacting leads modeled as Luttinger liquids. We show that interactions enhance the energy gap opened by the periodic potential and thus the robustness of the Thouless motor against variations in the chemical potential. We show that the motor degree of freedom can be described as a mobile impurity in a Luttinger liquid obeying Langevin dynamics with renormalized coefficients due to interactions, for which we give explicit expressions.

  7. Rotational ratchets with dipolar interactions.

    PubMed

    Jäger, Sebastian; Klapp, Sabine H L

    2012-12-01

    We report results from a computer simulation study on the rotational ratchet effect in systems of magnetic particles interacting via dipolar interactions. The ratchet effect consists of directed rotations of the particles in an oscillating magnetic field, which lacks a net rotating component. Our investigations are based on Brownian dynamics simulations of such many-particle systems. We investigate the influence of both the random and deterministic contributions to the equations of motion on the ratchet effect. As a main result, we show that dipolar interactions can have an enhancing as well as a dampening effect on the ratchet behavior depending on the dipolar coupling strength of the system under consideration. The enhancement is shown to be caused by an increase in the effective field on a particle generated by neighboring magnetic particles, while the dampening is due to restricted rotational motion in the effective field. Moreover, we find a nontrivial influence of the short-range, repulsive interaction between the particles.

  8. Natural Human-Computer Interaction

    NASA Astrophysics Data System (ADS)

    D'Amico, Gianpaolo; Del Bimbo, Alberto; Dini, Fabrizio; Landucci, Lea; Torpei, Nicola

    Research work in relation to Natural Human-Computer Interaction concerns the theorization and development of systems that understand and recognize human communicative actions in order to engage people in a dialogue between them and their surroundings.

  9. Mediated Character of Economic Interactions

    NASA Astrophysics Data System (ADS)

    Stepanic, Josip; Bertovic, Igor; Kasac, Josip

    2003-06-01

    Economic interactions are conducted between economic agents - individuals and collectives, through exchange of natural or artificial entities - goods, services and money, in a myriad of combinations. In this article we adopt a microscopic point of view, concentrate on the exchanged entities, and extract their relevant attributes as seen from structurally simple economic processes. Following that, we approach the interpretation of the economic interactions with their mediated character emphasized. Mediators of the interaction are locally available environment units. They are locally recognized and appropriately interpreted in a given value set as goods and money. The overall intensity of economic interactions considered is related to mediators' spatial and temporal characteristics. Extracted characteristics of mediators and economic processes are compacted in the set of formal rules. The approach is connected with similar approaches in economy and physics.

  10. Creep-Fatigue Interaction Testing

    NASA Technical Reports Server (NTRS)

    Halford, Gary R.

    2001-01-01

    Fatigue fives in metals are nominally time independent below 0.5 T(sub Melt). At higher temperatures, fatigue lives are altered due to time-dependent, thermally activated creep. Conversely, creep rates are altered by super. imposed fatigue loading. Creep and fatigue generally interact synergistically to reduce material lifetime. Their interaction, therefore, is of importance to structural durability of high-temperature structures such as nuclear reactors, reusable rocket engines, gas turbine engines, terrestrial steam turbines, pressure vessel and piping components, casting dies, molds for plastics, and pollution control devices. Safety and lifecycle costs force designers to quantify these interactions. Analytical and experimental approaches to creep-fatigue began in the era following World War II. In this article experimental and life prediction approaches are reviewed for assessing creep-fatigue interactions of metallic materials. Mechanistic models are also discussed briefly.

  11. Increasing Positive Interactive Classroom Behavior

    ERIC Educational Resources Information Center

    Kotcher, Elaine; Doremus, Richard R.

    1973-01-01

    The question examined in this study was as follows: do teachers increase their positive classroom interactive behaviors as a result of training in systematic classroom observation techniques? (Authors/JA)

  12. Multipurpose interactive NASA information system

    NASA Technical Reports Server (NTRS)

    Hill, J. M.; Keefer, R. L.; Sanders, D. R.; Seitz, R. N.

    1979-01-01

    Multipurpose Interactive NASA Information System (MINIS) is data management system capable of retrieving descriptive data from LANDSAT photos. General enough to be used with other user-defined data bases, interactive data management and information retrieval system was especially developed for small and medium-sized computers. It uses free-form data base that allows one to create entirely new and different data bases and to control format of output products.

  13. Interactive Astronomical Data Analysis Facility

    NASA Technical Reports Server (NTRS)

    Klinglesmith, D. A., III

    1980-01-01

    A description is given of the Interactive Astronomical Data Analysis Facility (IADAF) which performs interactive analysis of astronomical data for resident and visiting scientists. The facilities include a Grant measuring engine, a PDS 1010A microdensitometer, a COMTAL image display system and a PDP 11/40 computer system. Both hardware and software systems are examined, including a description of thirteen overlay programs. Some uses of the IADAF are indicated.

  14. On transonic viscous inviscid interaction

    NASA Astrophysics Data System (ADS)

    Buldakov, E. V.; Ruban, A. I.

    2002-11-01

    The paper is concerned with the interaction between the boundary layer on a smooth body surface and the outer inviscid compressible flow in the vicinity of a sonic point. First, a family of local self-similar solutions of the Kármán Guderley equation describing the inviscid flow behaviour immediately outside the interaction region is analysed; one of them was found to be suitable for describing the boundary-layer separation. In this solution the pressure has a singularity at the sonic point with the pressure gradient on the body surface being inversely proportional to the cubic root dpw/dx [similar] ([minus sign]x)[minus sign]1/3 of the distance ([minus sign]x) from the sonic point. This pressure gradient causes the boundary layer to interact with the inviscid part of the flow. It is interesting that the skin friction in the boundary layer upstream of the interaction region shows a characteristic logarithmic decay which determines an unusual behaviour of the flow inside the interaction region. This region has a conventional triple-deck structure. To study the interactive flow one has to solve simultaneously the Prandtl boundary-layer equations in the lower deck which occupies a thin viscous sublayer near the body surface and the Kármán Guderley equations for the upper deck situated in the inviscid flow outside the boundary layer. In this paper a numerical solution of the interaction problem is constructed for the case when the separation region is entirely contained within the viscous sublayer and the inviscid part of the flow remains marginally supersonic. The solution proves to be non-unique, revealing a hysteresis character of the flow in the interaction region.

  15. Interaction of two collisionless shocks

    NASA Technical Reports Server (NTRS)

    Cargill, P. J.; Goodrich, C. C.; Papadopoulos, K.

    1986-01-01

    Kinetic simulations of the interaction between two collisionless shocks are presented. During the collision of two perpendicular shocks, the shock electromagnetic field structures pass through each other, while the previously shocked ions are kept separate by the electric field arising in the collision. When two supercritical shocks collide, a fraction of ions are accelerated up to an order of magnitude in energy by first being reflected at one shock, then interacting with the electric fields of the other shock.

  16. Natural interaction for unmanned systems

    NASA Astrophysics Data System (ADS)

    Taylor, Glenn; Purman, Ben; Schermerhorn, Paul; Garcia-Sampedro, Guillermo; Lanting, Matt; Quist, Michael; Kawatsu, Chris

    2015-05-01

    Military unmanned systems today are typically controlled by two methods: tele-operation or menu-based, search-andclick interfaces. Both approaches require the operator's constant vigilance: tele-operation requires constant input to drive the vehicle inch by inch; a menu-based interface requires eyes on the screen in order to search through alternatives and select the right menu item. In both cases, operators spend most of their time and attention driving and minding the unmanned systems rather than on being a warfighter. With these approaches, the platform and interface become more of a burden than a benefit. The availability of inexpensive sensor systems in products such as Microsoft Kinect™ or Nintendo Wii™ has resulted in new ways of interacting with computing systems, but new sensors alone are not enough. Developing useful and usable human-system interfaces requires understanding users and interaction in context: not just what new sensors afford in terms of interaction, but how users want to interact with these systems, for what purpose, and how sensors might enable those interactions. Additionally, the system needs to reliably make sense of the user's inputs in context, translate that interpretation into commands for the unmanned system, and give feedback to the user. In this paper, we describe an example natural interface for unmanned systems, called the Smart Interaction Device (SID), which enables natural two-way interaction with unmanned systems including the use of speech, sketch, and gestures. We present a few example applications SID to different types of unmanned systems and different kinds of interactions.

  17. Interactional Psychology and Organizational Behavior.

    DTIC Science & Technology

    1982-02-01

    7 A0-A113 1132 MI1CHIGAN STATE UNIV EAST LANSING DEPT OF PSYCHOLOGY F/6 5/10 INTERACTIONAL PSYCHOLOGY AND ORGANIZATIONAL BEHA VIOR. (U) FEB 82 8...j INTERACTIONAL PSYCHOLOGY AND ORGANIZATIONAL BEHAVIOR Benjamin Schneider Research Report No. 82.1 February 1982 The writing of this paper was...supported in part by the Organizational Effectiveness Research Programs, Psychological Sciences Division, Office of Naval Research under Contract No. N00014

  18. CP, T and fundamental interactions

    NASA Astrophysics Data System (ADS)

    Frère, Jean-Marie

    2012-03-01

    We discuss the importance of the CP (simultaneous particle-antiparticle and left-right permutation) and T (time reversal) symmetries in the context of fundamental interactions. We show that they may provide clues to go beyond the 4-D gauge interactions. We insist on the fact that T violation is not associated to a degradation (like in entropy), but simply characterised by different trajectories.

  19. Dynamic interactions in neural networks

    SciTech Connect

    Arbib, M.A. ); Amari, S. )

    1989-01-01

    The study of neural networks is enjoying a great renaissance, both in computational neuroscience, the development of information processing models of living brains, and in neural computing, the use of neurally inspired concepts in the construction of intelligent machines. This volume presents models and data on the dynamic interactions occurring in the brain, and exhibits the dynamic interactions between research in computational neuroscience and in neural computing. The authors present current research, future trends and open problems.

  20. NP_PAH_interaction dataset

    EPA Pesticide Factsheets

    Concentrations of different polyaromatic hydrocarbons in water before and after interaction with nanomaterials. The results show the capacity of engineer nanomaterials for adsorbing different organic pollutants. This dataset is associated with the following publication:Sahle-Demessie, E., A. Zhao, C. Han, B. Hann, and H. Grecsek. Interaction of engineered nanomaterials with hydrophobic organic pollutants.. Journal of Nanotechnology. Hindawi Publishing Corporation, New York, NY, USA, 27(28): 284003, (2016).

  1. Measurement of interaction between antiprotons.

    PubMed

    2015-11-19

    One of the primary goals of nuclear physics is to understand the force between nucleons, which is a necessary step for understanding the structure of nuclei and how nuclei interact with each other. Rutherford discovered the atomic nucleus in 1911, and the large body of knowledge about the nuclear force that has since been acquired was derived from studies made on nucleons or nuclei. Although antinuclei up to antihelium-4 have been discovered and their masses measured, little is known directly about the nuclear force between antinucleons. Here, we study antiproton pair correlations among data collected by the STAR experiment at the Relativistic Heavy Ion Collider (RHIC), where gold ions are collided with a centre-of-mass energy of 200 gigaelectronvolts per nucleon pair. Antiprotons are abundantly produced in such collisions, thus making it feasible to study details of the antiproton-antiproton interaction. By applying a technique similar to Hanbury Brown and Twiss intensity interferometry, we show that the force between two antiprotons is attractive. In addition, we report two key parameters that characterize the corresponding strong interaction: the scattering length and the effective range of the interaction. Our measured parameters are consistent within errors with the corresponding values for proton-proton interactions. Our results provide direct information on the interaction between two antiprotons, one of the simplest systems of antinucleons, and so are fundamental to understanding the structure of more-complex antinuclei and their properties.

  2. Distinguishing ordinal and disordinal interactions.

    PubMed

    Widaman, Keith F; Helm, Jonathan L; Castro-Schilo, Laura; Pluess, Michael; Stallings, Michael C; Belsky, Jay

    2012-12-01

    Re-parameterized regression models may enable tests of crucial theoretical predictions involving interactive effects of predictors that cannot be tested directly using standard approaches. First, we present a re-parameterized regression model for the Linear × Linear interaction of 2 quantitative predictors that yields point and interval estimates of 1 key parameter-the crossover point of predicted values-and leaves certain other parameters unchanged. We explain how resulting parameter estimates provide direct evidence for distinguishing ordinal from disordinal interactions. We generalize the re-parameterized model to Linear × Qualitative interactions, where the qualitative variable may have 2 or 3 categories, and then describe how to modify the re-parameterized model to test moderating effects. To illustrate our new approach, we fit alternate models to social skills data on 438 participants in the National Institute of Child Health and Human Development Study of Early Child Care. The re-parameterized regression model had point and interval estimates of the crossover point that fell near the mean on the continuous environment measure. The disordinal form of the interaction supported 1 theoretical model-differential-susceptibility-over a competing model that predicted an ordinal interaction. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  3. Interactions of Amelogenin with Phospholipids

    PubMed Central

    Lokappa, Sowmya Bekshe; Chandrababu, Karthik Balakrishna; Dutta, Kaushik; Perovic, Iva; Evans, John Spencer; Moradian-Oldak, Janet

    2015-01-01

    Amelogenin protein has the potential to interact with other enamel matrix proteins, mineral and cell surfaces. We investigated the interactions of recombinant amelogenin rP172 with small unilamellar vesicles as model membranes, towards the goal of understanding the mechanisms of amelogenin-cell interactions during amelogenesis. Dynamic light scattering (DLS), fluorescence spectroscopy, circular dichroism (CD) and nuclear magnetic resonance (NMR) were used. In the presence of phospholipid vesicles, a blue shift in the Trp fluorescence emission maxima of rP172 was observed (~334 nm) and the Trp residues of rP172 were inaccessible to the aqueous quencher acrylamide. Though in DLS studies we cannot exclude the possibility of fusion of liposomes as the result of amelogenin addition, NMR and CD studies revealed a disorder-order transition of rP172 in a model membrane environment. Strong FRET from Trp in rP172 to DNS–bound-phospholipid was observed, and fluorescence polarization studies indicated that rP172 interacted with the hydrophobic core region of model membranes. Our data suggest that amelogenin has ability to interact with phospholipids and that such interactions may play key roles in enamel biomineralization as well as reported amelogenin signaling activities. PMID:25298002

  4. Measurement of interaction between antiprotons

    DOE PAGES

    Adamczyk, L.; Adkins, J. K.; Agakishiev, G.; ...

    2015-11-04

    In this paper, one of the primary goals of nuclear physics is to understand the force between nucleons, which is a necessary step for understanding the structure of nuclei and how nuclei interact with each other. Rutherford discovered the atomic nucleus in 1911, and the large body of knowledge about the nuclear force that has since been acquired was derived from studies made on nucleons or nuclei. Although antinuclei up to antihelium-4 have been discovered and their masses measured, little is known directly about the nuclear force between antinucleons. Here, we study antiproton pair correlations among data collected by themore » STAR experiment at the Relativistic Heavy Ion Collider (RHIC), where gold ions are collided with a centre-of-mass energy of 200 gigaelectronvolts per nucleon pair. Antiprotons are abundantly produced in such collisions, thus making it feasible to study details of the antiproton–antiproton interaction. By applying a technique similar to Hanbury Brown and Twiss intensity interferometry, we show that the force between two antiprotons is attractive. In addition, we report two key parameters that characterize the corresponding strong interaction: the scattering length and the effective range of the interaction. Our measured parameters are consistent within errors with the corresponding values for proton–proton interactions. Our results provide direct information on the interaction between two antiprotons, one of the simplest systems of antinucleons, and so are fundamental to understanding the structure of more-complex antinuclei and their properties.« less

  5. Measurement of interaction between antiprotons

    NASA Astrophysics Data System (ADS)

    The Star Collaboration; Adamczyk, L.; Adkins, J. K.; Agakishiev, G.; Aggarwal, M. M.; Ahammed, Z.; Alekseev, I.; Alford, J.; Aparin, A.; Arkhipkin, D.; Aschenauer, E. C.; Averichev, G. S.; Bairathi, V.; Banerjee, A.; Bellwied, R.; Bhasin, A.; Bhati, A. K.; Bhattarai, P.; Bielcik, J.; Bielcikova, J.; Bland, L. C.; Bordyuzhin, I. G.; Bouchet, J.; Brandenburg, J. D.; Brandin, A. V.; Bunzarov, I.; Butterworth, J.; Caines, H.; Calderón de La Barca Sánchez, M.; Campbell, J. M.; Cebra, D.; Cervantes, M. C.; Chakaberia, I.; Chaloupka, P.; Chang, Z.; Chattopadhyay, S.; Chen, J. H.; Chen, X.; Cheng, J.; Cherney, M.; Christie, W.; Contin, G.; Crawford, H. J.; Das, S.; de Silva, L. C.; Debbe, R. R.; Dedovich, T. G.; Deng, J.; Derevschikov, A. A.; di Ruzza, B.; Didenko, L.; Dilks, C.; Dong, X.; Drachenberg, J. L.; Draper, J. E.; Du, C. M.; Dunkelberger, L. E.; Dunlop, J. C.; Efimov, L. G.; Engelage, J.; Eppley, G.; Esha, R.; Evdokimov, O.; Eyser, O.; Fatemi, R.; Fazio, S.; Federic, P.; Fedorisin, J.; Feng, Z.; Filip, P.; Fisyak, Y.; Flores, C. E.; Fulek, L.; Gagliardi, C. A.; Garand, D.; Geurts, F.; Gibson, A.; Girard, M.; Greiner, L.; Grosnick, D.; Gunarathne, D. S.; Guo, Y.; Gupta, A.; Gupta, S.; Guryn, W.; Hamad, A.; Hamed, A.; Haque, R.; Harris, J. W.; He, L.; Heppelmann, S.; Heppelmann, S.; Hirsch, A.; Hoffmann, G. W.; Hofman, D. J.; Horvat, S.; Huang, B.; Huang, H. Z.; Huang, X.; Huck, P.; Humanic, T. J.; Igo, G.; Jacobs, W. W.; Jang, H.; Jiang, K.; Judd, E. G.; Kabana, S.; Kalinkin, D.; Kang, K.; Kauder, K.; Ke, H. W.; Keane, D.; Kechechyan, A.; Khan, Z. H.; Kikoła, D. P.; Kisel, I.; Kisiel, A.; Klein, S.; Kochenda, L.; Koetke, D. D.; Kollegger, T.; Kosarzewski, L. K.; Kraishan, A. F.; Kravtsov, P.; Krueger, K.; Kulakov, I.; Kumar, L.; Kycia, R. A.; Lamont, M. A. C.; Landgraf, J. M.; Landry, K. D.; Lauret, J.; Lebedev, A.; Lednicky, R.; Lee, J. H.; Li, X.; Li, Z. M.; Li, Y.; Li, W.; Li, X.; Li, C.; Lisa, M. A.; Liu, F.; Ljubicic, T.; Llope, W. J.; Lomnitz, M.; Longacre, R. S.; Luo, X.; Ma, G. L.; Ma, R.; Ma, Y. G.; Ma, L.; Magdy, N.; Majka, R.; Manion, A.; Margetis, S.; Markert, C.; Masui, H.; Matis, H. S.; McDonald, D.; Meehan, K.; Minaev, N. G.; Mioduszewski, S.; Mishra, D.; Mohanty, B.; Mondal, M. M.; Morozov, D. A.; Mustafa, M. K.; Nandi, B. K.; Nasim, Md.; Nayak, T. K.; Nigmatkulov, G.; Nogach, L. V.; Noh, S. Y.; Novak, J.; Nurushev, S. B.; Odyniec, G.; Ogawa, A.; Oh, K.; Okorokov, V.; Olvitt, D.; Page, B. S.; Pak, R.; Pan, Y. X.; Pandit, Y.; Panebratsev, Y.; Pawlik, B.; Pei, H.; Perkins, C.; Peterson, A.; Pile, P.; Planinic, M.; Pluta, J.; Poljak, N.; Poniatowska, K.; Porter, J.; Posik, M.; Poskanzer, A. M.; Putschke, J.; Qiu, H.; Quintero, A.; Ramachandran, S.; Raniwala, R.; Raniwala, S.; Ray, R. L.; Ritter, H. G.; Roberts, J. B.; Rogachevskiy, O. V.; Romero, J. L.; Roy, A.; Ruan, L.; Rusnak, J.; Rusnakova, O.; Sahoo, N. R.; Sahu, P. K.; Sakrejda, I.; Salur, S.; Sandweiss, J.; Sarkar, A.; Schambach, J.; Scharenberg, R. P.; Schmah, A. M.; Schmidke, W. B.; Schmitz, N.; Seger, J.; Seyboth, P.; Shah, N.; Shahaliev, E.; Shanmuganathan, P. V.; Shao, M.; Sharma, M. K.; Sharma, B.; Shen, W. Q.; Shi, S. S.; Shou, Q. Y.; Sichtermann, E. P.; Sikora, R.; Simko, M.; Skoby, M. J.; Smirnov, N.; Smirnov, D.; Song, L.; Sorensen, P.; Spinka, H. M.; Srivastava, B.; Stanislaus, T. D. S.; Stepanov, M.; Stock, R.; Strikhanov, M.; Stringfellow, B.; Sumbera, M.; Summa, B.; Sun, Z.; Sun, X. M.; Sun, Y.; Sun, X.; Surrow, B.; Svirida, N.; Szelezniak, M. A.; Tang, Z.; Tang, A. H.; Tarnowsky, T.; Tawfik, A.; Thomas, J. H.; Timmins, A. R.; Tlusty, D.; Tokarev, M.; Trentalange, S.; Tribble, R. E.; Tribedy, P.; Tripathy, S. K.; Trzeciak, B. A.; Tsai, O. D.; Ullrich, T.; Underwood, D. G.; Upsal, I.; van Buren, G.; van Nieuwenhuizen, G.; Vandenbroucke, M.; Varma, R.; Vasiliev, A. N.; Vertesi, R.; Videbæk, F.; Viyogi, Y. P.; Vokal, S.; Voloshin, S. A.; Vossen, A.; Wang, G.; Wang, H.; Wang, J. S.; Wang, Y.; Wang, Y.; Wang, F.; Webb, J. C.; Webb, G.; Wen, L.; Westfall, G. D.; Wieman, H.; Wissink, S. W.; Witt, R.; Wu, Y. F.; Xiao, Z. G.; Xie, W.; Xin, K.; Xu, Y. F.; Xu, Q. H.; Xu, H.; Xu, N.; Xu, Z.; Yang, Y.; Yang, C.; Yang, S.; Yang, Y.; Yang, Q.; Ye, Z.; Yepes, P.; Yi, L.; Yip, K.; Yoo, I.-K.; Yu, N.; Zbroszczyk, H.; Zha, W.; Zhang, J. B.; Zhang, Z.; Zhang, J.; Zhang, S.; Zhang, X. P.; Zhang, J.; Zhang, Y.; Zhao, J.; Zhong, C.; Zhou, L.; Zhu, X.; Zoulkarneeva, Y.; Zyzak, M.

    2015-11-01

    One of the primary goals of nuclear physics is to understand the force between nucleons, which is a necessary step for understanding the structure of nuclei and how nuclei interact with each other. Rutherford discovered the atomic nucleus in 1911, and the large body of knowledge about the nuclear force that has since been acquired was derived from studies made on nucleons or nuclei. Although antinuclei up to antihelium-4 have been discovered and their masses measured, little is known directly about the nuclear force between antinucleons. Here, we study antiproton pair correlations among data collected by the STAR experiment at the Relativistic Heavy Ion Collider (RHIC), where gold ions are collided with a centre-of-mass energy of 200 gigaelectronvolts per nucleon pair. Antiprotons are abundantly produced in such collisions, thus making it feasible to study details of the antiproton-antiproton interaction. By applying a technique similar to Hanbury Brown and Twiss intensity interferometry, we show that the force between two antiprotons is attractive. In addition, we report two key parameters that characterize the corresponding strong interaction: the scattering length and the effective range of the interaction. Our measured parameters are consistent within errors with the corresponding values for proton-proton interactions. Our results provide direct information on the interaction between two antiprotons, one of the simplest systems of antinucleons, and so are fundamental to understanding the structure of more-complex antinuclei and their properties.

  6. Interactions of amelogenin with phospholipids

    DOE PAGES

    Bekshe Lokappa, Sowmya; Chandrababu, Karthik Balakrishna; Dutta, Kaushik; ...

    2014-11-22

    Amelogenin protein has the potential to interact with other enamel matrix proteins, mineral, and cell surfaces. In this paper, we investigated the interactions of recombinant amelogenin rP172 with small unilamellar vesicles as model membranes, toward the goal of understanding the mechanisms of amelogenin–cell interactions during amelogenesis. Dynamic light scattering (DLS), fluorescence spectroscopy, circular dichroism (CD), and nuclear magnetic resonance (NMR) were used. In the presence of phospholipid vesicles, a blue shift in the Trp fluorescence emission maxima of rP172 was observed (~334 nm) and the Trp residues of rP172 were inaccessible to the aqueous quencher acrylamide. DLS studies indicated complexationmore » of rP172 and phospholipids, although the possibility of fusion of phospholipids following amelogenin addition cannot be ruled out. NMR and CD studies revealed a disorder–order transition of rP172 in a model membrane environment. Strong fluorescence resonance energy transfer from Trp in rP172 to DNS-bound-phospholipid was observed, and fluorescence polarization studies indicated that rP172 interacted with the hydrophobic core region of model membranes. Finally, our data suggest that amelogenin has ability to interact with phospholipids and that such interactions may play key roles in enamel biomineralization as well as reported amelogenin signaling activities.« less

  7. Warfarin interactions with medicinal herbs.

    PubMed

    Milić, Natasa; Milosević, Natasa; Golocorbin Kon, Svetlana; Bozić, Teodora; Abenavoli, Ludovico; Borrelli, Francesca

    2014-08-01

    Recognition of the adverse effects of medicinal herbs is not routine and the reports on such effects are even less frequent in clinical practice. Potential herb-drug interactions are of a major safety concern, especially for drugs with narrow therapeutic indices like warfarin, which can lead to severe adverse reactions that are sometimes life-threatening. The interactions between warfarin and medicinal herbs described in the literature have been summarized in this paper relying on Medline database (via PubMed) using the key words: warfarin, herbal supplements and interactions. The references on the analyzed literature have been investigated in order to collect the existing data. The case reports with severe adverse effects such as spontaneous postoperative bleeding, formation of hematomas, hematemesis, melena, thrombosis, subarachnoid hemorrhage and/or subdural hematomas after concomitant use of warfarin and the medicinal herbs: Panax ginseng, Hypericum perforatum, Salvia milthiorizza, Gingko biloba, Serenoa repens, Angelica sinensis, Vaccinium species, Allium sativum, Zingiber officinale, Tanacetum parthenium, Lucium barbarum, Matricaria chamomilla, Boswellia serrata and Camellia sinensis have been estimated. Some of the interactions between warfarin and medicinal herbs have been well assessed proving that they are closely-dependent. The interactions between warfarin and medicinal herbs, not generally reported in previous reviews, are presented in our review. The health professionals who are involved in treating the patients are expected to be fully informed about the interactions between warfarin and medicinal herbs in order to minimize the health risks of the patients.

  8. Measurement of interaction between antiprotons

    SciTech Connect

    Adamczyk, L.; Adkins, J. K.; Agakishiev, G.; Aggarwal, M. M.; Ahammed, Z.; Alekseev, I.; Alford, J.; Aparin, A.; Arkhipkin, D.; Aschenauer, E. C.; Averichev, G. S.; Bairathi, V.; Banerjee, A.; Bellwied, R.; Bhasin, A.; Bhati, A. K.; Bhattarai, P.; Bielcik, J.; Bielcikova, J.; Bland, L. C.; Bordyuzhin, I. G.; Bouchet, J.; Brandenburg, J. D.; Brandin, A. V.; Bunzarov, I.; Butterworth, J.; Caines, H.; Calderón de la Barca Sánchez, M.; Campbell, J. M.; Cebra, D.; Cervantes, M. C.; Chakaberia, I.; Chaloupka, P.; Chang, Z.; Chattopadhyay, S.; Chen, J. H.; Chen, X.; Cheng, J.; Cherney, M.; Christie, W.; Contin, G.; Crawford, H. J.; Das, S.; De Silva, L. C.; Debbe, R. R.; Dedovich, T. G.; Deng, J.; Derevschikov, A. A.; di Ruzza, B.; Didenko, L.; Dilks, C.; Dong, X.; Drachenberg, J. L.; Draper, J. E.; Du, C. M.; Dunkelberger, L. E.; Dunlop, J. C.; Efimov, L. G.; Engelage, J.; Eppley, G.; Esha, R.; Evdokimov, O.; Eyser, O.; Fatemi, R.; Fazio, S.; Federic, P.; Fedorisin, J.; Feng, Z.; Filip, P.; Fisyak, Y.; Flores, C. E.; Fulek, L.; Gagliardi, C. A.; Garand, D.; Geurts, F.; Gibson, A.; Girard, M.; Greiner, L.; Grosnick, D.; Gunarathne, D. S.; Guo, Y.; Gupta, A.; Gupta, S.; Guryn, W.; Hamad, A.; Hamed, A.; Haque, R.; Harris, J. W.; He, L.; Heppelmann, S.; Heppelmann, S.; Hirsch, A.; Hoffmann, G. W.; Hofman, D. J.; Horvat, S.; Huang, B.; Huang, H. Z.; Huang, X.; Huck, P.; Humanic, T. J.; Igo, G.; Jacobs, W. W.; Jang, H.; Jiang, K.; Judd, E. G.; Kabana, S.; Kalinkin, D.; Kang, K.; Kauder, K.; Ke, H. W.; Keane, D.; Kechechyan, A.; Khan, Z. H.; Kikoła, D. P.; Kisel, I.; Kisiel, A.; Klein, S.; Kochenda, L.; Koetke, D. D.; Kollegger, T.; Kosarzewski, L. K.; Kraishan, A. F.; Kravtsov, P.; Krueger, K.; Kulakov, I.; Kumar, L.; Kycia, R. A.; Lamont, M. A. C.; Landgraf, J. M.; Landry, K. D.; Lauret, J.; Lebedev, A.; Lednicky, R.; Lee, J. H.; Li, X.; Li, Z. M.; Li, Y.; Li, W.; Li, X.; Li, C.; Lisa, M. A.; Liu, F.; Ljubicic, T.; Llope, W. J.; Lomnitz, M.; Longacre, R. S.; Luo, X.; Ma, G. L.; Ma, R.; Ma, Y. G.; Ma, L.; Magdy, N.; Majka, R.; Manion, A.; Margetis, S.; Markert, C.; Masui, H.; Matis, H. S.; McDonald, D.; Meehan, K.; Minaev, N. G.; Mioduszewski, S.; Mishra, D.; Mohanty, B.; Mondal, M. M.; Morozov, D. A.; Mustafa, M. K.; Nandi, B. K.; Nasim, Md.; Nayak, T. K.; Nigmatkulov, G.; Nogach, L. V.; Noh, S. Y.; Novak, J.; Nurushev, S. B.; Odyniec, G.; Ogawa, A.; Oh, K.; Okorokov, V.; Olvitt, D.; Page, B. S.; Pak, R.; Pan, Y. X.; Pandit, Y.; Panebratsev, Y.; Pawlik, B.; Pei, H.; Perkins, C.; Peterson, A.; Pile, P.; Planinic, M.; Pluta, J.; Poljak, N.; Poniatowska, K.; Porter, J.; Posik, M.; Poskanzer, A. M.; Putschke, J.; Qiu, H.; Quintero, A.; Ramachandran, S.; Raniwala, R.; Raniwala, S.; Ray, R. L.; Ritter, H. G.; Roberts, J. B.; Rogachevskiy, O. V.; Romero, J. L.; Roy, A.; Ruan, L.; Rusnak, J.; Rusnakova, O.; Sahoo, N. R.; Sahu, P. K.; Sakrejda, I.; Salur, S.; Sandweiss, J.; Sarkar, A.; Schambach, J.; Scharenberg, R. P.; Schmah, A. M.; Schmidke, W. B.; Schmitz, N.; Seger, J.; Seyboth, P.; Shah, N.; Shahaliev, E.; Shanmuganathan, P. V.; Shao, M.; Sharma, M. K.; Sharma, B.; Shen, W. Q.; Shi, S. S.; Shou, Q. Y.; Sichtermann, E. P.; Sikora, R.; Simko, M.; Skoby, M. J.; Smirnov, N.; Smirnov, D.; Song, L.; Sorensen, P.; Spinka, H. M.; Srivastava, B.; Stanislaus, T. D. S.; Stepanov, M.; Stock, R.; Strikhanov, M.; Stringfellow, B.; Sumbera, M.; Summa, B.; Sun, Z.; Sun, X. M.; Sun, Y.; Sun, X.; Surrow, B.; Svirida, N.; Szelezniak, M. A.; Tang, Z.; Tang, A. H.; Tarnowsky, T.; Tawfik, A.; Thomas, J. H.; Timmins, A. R.; Tlusty, D.; Tokarev, M.; Trentalange, S.; Tribble, R. E.; Tribedy, P.; Tripathy, S. K.; Trzeciak, B. A.; Tsai, O. D.; Ullrich, T.; Underwood, D. G.; Upsal, I.; Van Buren, G.; van Nieuwenhuizen, G.; Vandenbroucke, M.; Varma, R.; Vasiliev, A. N.; Vertesi, R.; Videbæk, F.; Viyogi, Y. P.; Vokal, S.; Voloshin, S. A.; Vossen, A.; Wang, G.; Wang, H.; Wang, J. S.; Wang, Y.; Wang, Y.; Wang, F.; Webb, J. C.; Webb, G.; Wen, L.; Westfall, G. D.; Wieman, H.; Wissink, S. W.; Witt, R.; Wu, Y. F.; Xiao, Z. G.; Xie, W.; Xin, K.; Xu, Y. F.; Xu, Q. H.; Xu, H.; Xu, N.; Xu, Z.; Yang, Y.; Yang, C.; Yang, S.; Yang, Y.; Yang, Q.; Ye, Z.; Yepes, P.; Yi, L.; Yip, K.; Yoo, I. -K.; Yu, N.; Zbroszczyk, H.; Zha, W.; Zhang, J. B.; Zhang, Z.; Zhang, J.; Zhang, S.; Zhang, X. P.; Zhang, J.; Zhang, Y.; Zhao, J.; Zhong, C.; Zhou, L.; Zhu, X.; Zoulkarneeva, Y.; Zyzak, M.

    2015-11-04

    In this paper, one of the primary goals of nuclear physics is to understand the force between nucleons, which is a necessary step for understanding the structure of nuclei and how nuclei interact with each other. Rutherford discovered the atomic nucleus in 1911, and the large body of knowledge about the nuclear force that has since been acquired was derived from studies made on nucleons or nuclei. Although antinuclei up to antihelium-4 have been discovered and their masses measured, little is known directly about the nuclear force between antinucleons. Here, we study antiproton pair correlations among data collected by the STAR experiment at the Relativistic Heavy Ion Collider (RHIC), where gold ions are collided with a centre-of-mass energy of 200 gigaelectronvolts per nucleon pair. Antiprotons are abundantly produced in such collisions, thus making it feasible to study details of the antiproton–antiproton interaction. By applying a technique similar to Hanbury Brown and Twiss intensity interferometry, we show that the force between two antiprotons is attractive. In addition, we report two key parameters that characterize the corresponding strong interaction: the scattering length and the effective range of the interaction. Our measured parameters are consistent within errors with the corresponding values for proton–proton interactions. Our results provide direct information on the interaction between two antiprotons, one of the simplest systems of antinucleons, and so are fundamental to understanding the structure of more-complex antinuclei and their properties.

  9. Interactions of amelogenin with phospholipids

    SciTech Connect

    Bekshe Lokappa, Sowmya; Chandrababu, Karthik Balakrishna; Dutta, Kaushik; Perovic, Iva; Evans, John Spencer; Moradian-Oldak, Janet

    2014-11-22

    Amelogenin protein has the potential to interact with other enamel matrix proteins, mineral, and cell surfaces. In this paper, we investigated the interactions of recombinant amelogenin rP172 with small unilamellar vesicles as model membranes, toward the goal of understanding the mechanisms of amelogenin–cell interactions during amelogenesis. Dynamic light scattering (DLS), fluorescence spectroscopy, circular dichroism (CD), and nuclear magnetic resonance (NMR) were used. In the presence of phospholipid vesicles, a blue shift in the Trp fluorescence emission maxima of rP172 was observed (~334 nm) and the Trp residues of rP172 were inaccessible to the aqueous quencher acrylamide. DLS studies indicated complexation of rP172 and phospholipids, although the possibility of fusion of phospholipids following amelogenin addition cannot be ruled out. NMR and CD studies revealed a disorder–order transition of rP172 in a model membrane environment. Strong fluorescence resonance energy transfer from Trp in rP172 to DNS-bound-phospholipid was observed, and fluorescence polarization studies indicated that rP172 interacted with the hydrophobic core region of model membranes. Finally, our data suggest that amelogenin has ability to interact with phospholipids and that such interactions may play key roles in enamel biomineralization as well as reported amelogenin signaling activities.

  10. Technology Adoption: an Interaction Perspective

    NASA Astrophysics Data System (ADS)

    Sitorus, Hotna M.; Govindaraju, Rajesri; Wiratmadja, I. I.; Sudirman, Iman

    2016-02-01

    The success of a new technology depends on how well it is accepted by its intended users. Many technologies face the problem of low adoption rate, despite the benefits. An understanding of what makes people accept or reject a new technology can help speed up the adoption rate. This paper presents a framework for technology adoption based on an interactive perspective, resulting from a literature study on technology adoption. In studying technology adoption, it is necessary to consider the interactions among elements involved in the system, for these interactions may generate new characteristics or new relationships. The interactions among elements in a system adoption have not received sufficient consideration in previous studies of technology adoption. Based on the proposed interaction perspective, technology adoption is elaborated by examining interactions among the individual (i.e. the user or prospective user), the technology, the task and the environment. The framework is formulated by adopting several theories, including Perceived Characteristics of Innovating, Diffusion of Innovation Theory, Technology Acceptance Model, Task-Technology Fit and usability theory. The proposed framework is illustrated in the context of mobile banking adoption. It is aimed to offer a better understanding of determinants of technology adoption in various contexts, including technology in manufacturing systems.

  11. Three-baryon interaction generated by determinant interaction of quarks

    NASA Astrophysics Data System (ADS)

    Ohnishi, Akira; Kashiwa, Kouji; Morita, Kenji

    2017-07-01

    We discuss the 3-baryon interaction generated by the determinant interaction of quarks, known as the Kobayashi-Maskawa-'t Hooft (KMT) interaction. The expectation value of the KMT interaction operator is calculated in fully antisymmetrized quark-cluster model wave functions for 1-, 2-, and 3-octet-baryon states. The 3-baryon potential from the KMT interaction is found to be repulsive for NNΛ and NΛΛ systems, while it is zero for the NNN system. The strength and range of the 3-baryon potential are found to be comparable to those for the NNN 3-body potential obtained in lattice QCD simulations. The contribution to the Λ single particle potential in nuclear matter is found to be 0.28{ MeV} and 0.73{ MeV} in neutron matter and symmetric nuclear matter at normal nuclear density, respectively. These repulsive forces are not enough to solve the hyperon puzzle, but may be measured in high-precision hyperisotope experiments.

  12. Two experimental case studies of interacting swash events: a strong interaction and a weak interaction

    NASA Astrophysics Data System (ADS)

    Pujara, N.; Liu, P. L. F.

    2016-12-01

    The swash zone - the subregion of the nearshore that is periodically covered by flowing water due to waves - is an important, dynamic area for sediment transport and beach morphology. On natural beaches successive swash events and their mutual interactions are commonplace, which may lead to enhanced sediment transport and wave run-up. We present measurements of bed shear stress, bed pressure, and free-surface displacement from large-scale experiments to understand the dynamics of the boundary layer during swash interactions. We find that the dimensionless swash period, i.e., the ratio of the time period of swash to the time separation of successive wave crests, plays an important role in determining qualitative character of the swash-swash interaction. We also link this dimensionless swash period to the wave breaker type through the surf similarity parameter, providing a way to predict the qualitative behaviour of swash interactions from limited knowledge of incident waves.

  13. A Taxonomy of Interaction for Instructional Multimedia.

    ERIC Educational Resources Information Center

    Schwier, Richard A.

    This paper rejects the hardware-based "levels of interaction" made popular in interactive video literature to describe human-machine interaction in favor of a new taxonomy of learner-media interaction based on the type of cognitive engagement experienced by learners. Interaction can be described on three levels, based on the quality of…

  14. Stand By for Fun: Experience and Interaction.

    ERIC Educational Resources Information Center

    Crockford, Douglas

    1986-01-01

    This paper explores interactivity, and considers what should be done to create a mass market for interactive media. It is suggested that one way to do so is to examine the video game phenomenon, and a model of interactivity is proposed. The model, a "home interactive theater," would involve interaction in the telling of a story, with the…

  15. Environmental interactions in space exploration: Environmental interactions working group

    NASA Technical Reports Server (NTRS)

    Kolecki, Joseph C.; Hillard, G. Barry

    1992-01-01

    With the advent of the Space Exploration Initiative, the possibility of designing and using systems on scales heretofore unattempted presents exciting new challenges in systems design and space science. The environments addressed by the Space Exploration Initiative include the surfaces of the Moon and Mars, as well as the varied plasma and field environments which will be encountered by humans and cargo enroute to these destinations. Systems designers will need to understand environmental interactions and be able to model these mechanisms from the earliest conceptual design stages through design completion. To the end of understanding environmental interactions and establishing robotic precursor mission requirements, an Environmental Interactions Working Group was established as part of the Robotic Missions Working Group. The working group is described, and its current activities are updated.

  16. Weakly Interacting Disordered Electron Systems

    NASA Astrophysics Data System (ADS)

    Ekuma, C. E.; Terletska, H.; Yang, S.; Tam, K.-M.; Vidhyadhiraja, N. S.; Moreno, J.; Jarrell, M.

    2015-03-01

    We report on the interplay of interactions and disorder within the typical medium dynamical cluster approximation using the Anderson-Hubbard model. By the systematical incorporation of non-local spatial correlations and the diagonal disorder on an equal footing, we study the initial effects of electron interactions (U) in one (1D), two (2D), and three (3D) dimensions. Treating the interacting non-local cluster self-energy (Σc(SOPT) [ cal G ~ ] (i , j ≠ i)) up to U2 order in the perturbation expansion, we obtain the ground-state phase diagram in 3D for the disorder induced paramagnetic metal to insulator transition in the presence of weak interactions. We find that the critical disorder strength (Wc), required to localize all states, increases with increasing U; implying that the metallic phase is stabilized by interactions. In 2D, our results agree with previous findings on the destruction of the insulating phase by U, while in 1D, we find strong competition between both phases. This work is supported by the NSF EPSCoR EPS-1003897. Supercomputer support is provided by LONI and HPC@LSU.

  17. Intermolecular interactions in solid benzene.

    PubMed

    Kearley, G J; Johnson, M R; Tomkinson, J

    2006-01-28

    The lattice dynamics and molecular vibrations of benzene and deuterated benzene crystals are calculated from force constants derived from density-functional theory (DFT) calculations and compared with measured inelastic neutron-scattering spectra. A very small change (0.5%) in lattice parameter is required to obtain real lattice-mode frequencies across the Brillouin zone. There is a strong coupling between wagging and breathing modes away from the zone center. This coupling and sensitivity to cell size arises from two basic interactions. Firstly, comparatively strong interactions that hold the benzene molecules together in layers. These include an intermolecular interaction in which H atoms of one molecule link to the center of the aromatic ring of a neighboring molecule. The layers are held to each other by weaker interactions, which also have components that hold molecules together within a layer. Small changes in the lattice parameters change this second type of interaction and account for the changes to the lattice dynamics. The calculations also reveal a small auxetic effect in that elongation of the crystal along the b axis leads to an increase in internal pressure in the ac plane, that is, elongation in the b direction induces expansion in the a and c directions.

  18. Drug interactions and the statins

    PubMed Central

    Herman, R J

    1999-01-01

    Drug interactions commonly occur in patients receiving treatment with multiple medications. Most interactions remain unrecognized because drugs, in general, have a wide margin of safety or because the extent of change in drug levels is small when compared with the variation normally seen in clinical therapy. All drug interactions have a pharmacokinetic or pharmacodynamic basis and are predictable given an understanding of the pharmacology of the drugs involved. Drugs most liable to pose problems are those having concentration-dependent toxicity within, or close to, the therapeutic range; those with steep dose-response curves; those having high first-pass metabolism or those with a single, inhibitable route of elimination. Knowing which drugs possess these intrinsic characteristics, together with a knowledge of hepatic P-450 metabolism and common enzyme-inducing and enzyme-inhibiting drugs, can greatly assist physicians in predicting interactions that may be clinically relevant. This article reviews the pharmacology of drug interactions that can occur with hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) to illustrate the scope of the problem and the ways in which physicians may manage this important therapeutic class of drugs. PMID:10584091

  19. Field Theory of Fundamental Interactions

    NASA Astrophysics Data System (ADS)

    Wang, Shouhong; Ma, Tian

    2017-01-01

    First, we present two basic principles, the principle of interaction dynamics (PID) and the principle of representation invariance (PRI). Intuitively, PID takes the variation of the action under energy-momentum conservation constraint. We show that the PID is the requirement of the presence of dark matter and dark energy, the Higgs field and the quark confinement. PRI requires that the SU(N) gauge theory be independent of representations of SU(N). It is clear that PRI is the logic requirement of any gauge theory. With PRI, we demonstrate that the coupling constants for the strong and the weak interactions are the main sources of these two interactions, reminiscent of the electric charge. Second, we emphasize that symmetry principles-the principle of general relativity and the principle of Lorentz invariance and gauge invariance-together with the simplicity of laws of nature, dictate the actions for the four fundamental interactions. Finally, we show that the PID and the PRI, together with the symmetry principles give rise to a unified field model for the fundamental interactions, which is consistent with current experimental observations and offers some new physical predictions. The research is supported in part by the National Science Foundation (NSF) grant DMS-1515024, and by the Office of Naval Research (ONR) grant N00014-15-1-2662.

  20. Information capacity of specific interactions

    PubMed Central

    Huntley, Miriam H.; Murugan, Arvind; Brenner, Michael P.

    2016-01-01

    Specific interactions are a hallmark feature of self-assembly and signal-processing systems in both synthetic and biological settings. Specificity between components may arise from a wide variety of physical and chemical mechanisms in diverse contexts, from DNA hybridization to shape-sensitive depletion interactions. Despite this diversity, all systems that rely on interaction specificity operate under the constraint that increasing the number of distinct components inevitably increases off-target binding. Here we introduce “capacity,” the maximal information encodable using specific interactions, to compare specificity across diverse experimental systems and to compute how specificity changes with physical parameters. Using this framework, we find that “shape” coding of interactions has higher capacity than chemical (“color”) coding because the strength of off-target binding is strongly sublinear in binding-site size for shapes while being linear for colors. We also find that different specificity mechanisms, such as shape and color, can be combined in a synergistic manner, giving a capacity greater than the sum of the parts. PMID:27155013

  1. Motor interference in interactive contexts

    PubMed Central

    Chinellato, Eris; Castiello, Umberto; Sartori, Luisa

    2015-01-01

    Action observation and execution share overlapping neural substrates, so that simultaneous activation by observation and execution modulates motor performance. Previous literature on simple prehension tasks has revealed that motor influence can be two-sided: facilitation for observed and performed congruent actions and interference for incongruent actions. But little is known of the specific modulations of motor performance in complex forms of interaction. Is it possible that the very same observed movement can lead either to interference or facilitation effects on a temporally overlapping congruent executed action, depending on the context? To answer this question participants were asked to perform a reach-to-grasp movement adopting a precision grip (PG) while: (i) observing a fixation cross, (ii) observing an actor performing a PG with interactive purposes, (iii) observing an actor performing a PG without interactive purposes. In particular, in the interactive condition the actor was shown trying to pour some sugar on a large cup located out of her reach but close to the participant watching the video, thus eliciting in reaction a complementary whole-hand grasp. Notably, fine-grained kinematic analysis for this condition revealed a specific delay in the grasping and reaching components and an increased trajectory deviation despite the observed and executed movement’s congruency. Moreover, early peaks of trajectory deviation seem to indicate that socially relevant stimuli are acknowledged by the motor system very early. These data suggest that interactive contexts can determine a prompt modulation of stimulus–response compatibility effects. PMID:26113835

  2. Platelet interaction with polymerizing fibrin.

    PubMed

    Niewiarowski, S; Regoeczi, E; Stewart, G J; Senyl, A F; Mustard, J F

    1972-03-01

    Interaction of washed pig, rabbit, or human platelets with fibrinogen was studied during its transition to fibrin using photometric, isotopic, and electron microscopic techniques. Untreated fibrinogen and fully polymerized fibrin had no detectable effect on platelets. Fibrinogen, incubated with low concentrations of reptilase or thrombin, formed intermediate products which readily became associated with platelets and caused their aggregation. Neutralization of the thrombin did not prevent this interaction. In the absence of fibrinogen, reptilase did not affect platelets. The interaction of polymerizing fibrin with platelets was accompanied by small losses of platelet constituents (serotonin, adenine nucleotides, platelet factor 4, and lactic dehydrogenase). This loss did not appear to be the result of the platelet release reaction. Inhibitors of the release reaction or of adenosine diphosphate (ADP)-induced aggregation did not prevent the interaction of platelets with polymerizing fibrin. Apyrase or prostaglandin E(1) (PGE(1)) reduced the extent of platelet aggregation by polymerizing fibrin, but the amount of protein associated with platelets was slightly increased. The interaction of polymerizing fibrin with platelets was completely inhibited by ethylenediaminetetraacetate (EDTA) or ethylene glycol bis (beta-aminoethyl ether) N, N,N',N'-tetraacetic acid (EGTA).Fibers formed in solutions of polymerizing fibrin were larger in the presence than in the absence of washed platelets, suggesting that platelets affect fibrin polymerization. The adherence of platelets to polymerizing fibrin may be responsible for the establishment of links between platelets and fibrin in hemostatic plugs and thrombi.

  3. Quantum simulation with interacting photons

    NASA Astrophysics Data System (ADS)

    Hartmann, Michael J.

    2016-10-01

    Enhancing optical nonlinearities so that they become appreciable on the single photon level and lead to nonclassical light fields has been a central objective in quantum optics for many years. After this has been achieved in individual micro-cavities representing an effectively zero-dimensional volume, this line of research has shifted its focus towards engineering devices where such strong optical nonlinearities simultaneously occur in extended volumes of multiple nodes of a network. Recent technological progress in several experimental platforms now opens the possibility to employ the systems of strongly interacting photons, these give rise to as quantum simulators. Here we review the recent development and current status of this research direction for theory and experiment. Addressing both, optical photons interacting with atoms and microwave photons in networks of superconducting circuits, we focus on analogue quantum simulations in scenarios where effective photon-photon interactions exceed dissipative processes in the considered platforms.

  4. Magnetic activity of interacting binaries

    NASA Astrophysics Data System (ADS)

    Hill, Colin A.

    2017-10-01

    Interacting binaries provide unique parameter regimes, both rapid rotation and tidal distortion, in which to test stellar dynamo theories and study the resulting magnetic activity. Close binaries such as cataclysmic variables (CVs) have been found to differentially rotate, and so can provide testbeds for tidal dissipation efficiency in stellar convective envelopes, with implications for both CV and planet-star evolution. Furthermore, CVs show evidence of preferential emergence of magnetic flux tubes towards the companion star, as well as large, long-lived prominences that form preferentially within the binary geometry. Moreover, RS CVn binaries also show clear magnetic interactions between the two components in the form of coronal X-ray emission. Here, we review several examples of magnetic interactions in different types of close binaries.

  5. Experimental coevolution of species interactions.

    PubMed

    Brockhurst, Michael A; Koskella, Britt

    2013-06-01

    Coevolution, the process of reciprocal adaptation and counter-adaptation between ecologically interacting species, affects most organisms and is considered a key force structuring biological diversity. Our understanding of the pattern and process of coevolution, particularly of antagonistic species interactions, has been hugely advanced in recent years by an upsurge in experimental studies that directly observe coevolution in the laboratory. These experiments pose new questions by revealing novel facets of the coevolutionary process not captured by current theory, while also providing the first empirical tests of longstanding coevolutionary ideas, including the influential Red Queen hypothesis. In this article, we highlight emerging directions for this field, including experimental coevolution of mutualistic interactions and understanding how pairwise coevolutionary processes scale up within species-rich communities. Copyright © 2013 Elsevier Ltd. All rights reserved.

  6. Hairpin Vortices: Autogeneration and Interaction

    NASA Astrophysics Data System (ADS)

    Sabatino, Daniel; Maharjan, Rijan; Sanders, Andrew

    2013-11-01

    The regeneration of hairpin vortices is examined in a free-surface water channel where vortices are artificially generated by means of injection in a laminar boundary layer. The process is visualized with dye and hydrogen bubble-wire techniques. The strength of an isolated hairpin required to begin the autogeneration process is established by means of PIV measurements on the symmetry plane. Because hairpins are in close proximity in a fully-turbulent boundary layer, two hairpins are generated at different streamwise locations and allowed to interact at different stages of development. The relative position, strength and maturity of the interacting hairpins that generate secondary vortices are examined. The morphology of the generation process and of the resulting secondary hairpin for both the isolated and interacting cases are discussed and compared to previous work. Supported by the National Science Foundation under Grant CBET-1040236.

  7. Interactions between comoving magnetic microswimmers.

    PubMed

    Keaveny, Eric E; Maxey, Martin R

    2008-04-01

    The artificial microswimmer [R. Dreyfus, Nature (London) 437, 862 (2005)] whose mechanism of propulsion is the magnetically driven undulation of a flagellum-like tail composed of chemically linked paramagnetic beads can be used as a physical model with which to study low-Reynolds-number swimming. Understanding how such swimmers interact provides insight into the related problem of quantifying the hydrodynamic interactions between microorganisms. In this study, particle-based numerical simulations are conducted of two comoving artificial swimmers. The resulting swimming speeds are determined over a range of separations for swimmers driven by planar and rotational magnetic fields. The far-field hydrodynamic interactions are analyzed and found to decay as h(-2) where h is the separation distance. Additionally, the role of the interswimmer magnetic forces is determined.

  8. The nitrogen cycle: Atmosphere interactions

    NASA Technical Reports Server (NTRS)

    Levine, J. S.

    1984-01-01

    Atmospheric interactions involving the nitrogen species are varied and complex. These interactions include photochemical reactions, initiated by the absorption of solar photons and chemical kinetic reactions, which involve both homogeneous (gas-to-gas reactions) and heterogeneous (gas-to-particle) reactions. Another important atmospheric interaction is the production of nitrogen oxides by atmospheric lightning. The nitrogen cycle strongly couples the biosphere and atmosphere. Many nitrogen species are produced by biogenic processes. Once in the atmosphere nitrogen oxides are photochemically and chemically transformed to nitrates, which are returned to the biosphere via precipitation, dry deposition and aerosols to close the biosphere-atmosphere nitrogen cycle. The sources, sinks and photochemistry/chemistry of the nitrogen species; atmospheric nitrogen species; souces and sinks of nitrous oxide; sources; sinks and photochemistry/chemistry of ammonia; seasonal variation of the vertical distribution of ammonia in the troposphere; surface and atmospheric sources of the nitrogen species, and seasonal variation of ground level ammonia are summarized.

  9. Interactive autonomy and robotic skills

    NASA Technical Reports Server (NTRS)

    Kellner, A.; Maediger, B.

    1994-01-01

    Current concepts of robot-supported operations for space laboratories (payload servicing, inspection, repair, and ORU exchange) are mainly based on the concept of 'interactive autonomy' which implies autonomous behavior of the robot according to predefined timelines, predefined sequences of elementary robot operations and within predefined world models supplying geometrical and other information for parameter instantiation on the one hand, and the ability to override and change the predefined course of activities by human intervention on the other hand. Although in principle a very powerful and useful concept, in practice the confinement of the robot to the abstract world models and predefined activities appears to reduce the robot's stability within real world uncertainties and its applicability to non-predefined parts of the world, calling for frequent corrective interaction by the operator, which in itself may be tedious and time-consuming. Methods are presented to improve this situation by incorporating 'robotic skills' into the concept of interactive autonomy.

  10. Hadronization processes in neutrino interactions

    SciTech Connect

    Katori, Teppei; Mandalia, Shivesh

    2015-10-15

    Next generation neutrino oscillation experiments utilize details of hadronic final states to improve the precision of neutrino interaction measurements. The hadronic system was often neglected or poorly modelled in the past, but they have significant effects on high precision neutrino oscillation and cross-section measurements. Among the physics of hadronic systems in neutrino interactions, the hadronization model controls multiplicities and kinematics of final state hadrons from the primary interaction vertex. For relatively high invariant mass events, many neutrino experiments rely on the PYTHIA program. Here, we show a possible improvement of this process in neutrino event generators, by utilizing expertise from the HERMES experiment. Finally, we estimate the impact on the systematics of hadronization models for neutrino mass hierarchy analysis using atmospheric neutrinos such as the PINGU experiment.

  11. Studies of food drug interactions.

    PubMed

    Aman, Syed Faisal; Hassan, Fouzia; Naqvi, Baqar S; Hasan, Syed Muhammmad Farid

    2010-07-01

    Medicines can treat and alleviate many diseases provided that they must be taken properly to ensure that they are safe and useful. One issue related with the medicines is that whether to take on empty stomach or with food. The present work gives information regarding food-drug interactions that were studied by collecting seventy five prescriptions from various hospitals. In most of the collected prescriptions, food-drug interactions were detected using the literature available. It was also found that only few studies have been carried out so far on the effect of food on drug disposition in the Asian population. Thus more studies on food-drug interactions particularly in the local population is recommended in order to determine the effect of food and food components on drug disposition and to the kinetics of the drugs which has not yet well highlighted in this part of the world.

  12. Bacterial Communities: Interactions to Scale

    PubMed Central

    Stubbendieck, Reed M.; Vargas-Bautista, Carol; Straight, Paul D.

    2016-01-01

    In the environment, bacteria live in complex multispecies communities. These communities span in scale from small, multicellular aggregates to billions or trillions of cells within the gastrointestinal tract of animals. The dynamics of bacterial communities are determined by pairwise interactions that occur between different species in the community. Though interactions occur between a few cells at a time, the outcomes of these interchanges have ramifications that ripple through many orders of magnitude, and ultimately affect the macroscopic world including the health of host organisms. In this review we cover how bacterial competition influences the structures of bacterial communities. We also emphasize methods and insights garnered from culture-dependent pairwise interaction studies, metagenomic analyses, and modeling experiments. Finally, we argue that the integration of multiple approaches will be instrumental to future understanding of the underlying dynamics of bacterial communities. PMID:27551280

  13. Fluctuating hyperfine interactions: computational implementation

    NASA Astrophysics Data System (ADS)

    Zacate, M. O.; Evenson, W. E.

    2010-04-01

    A library of computational routines has been created to assist in the analysis of stochastic models of hyperfine interactions. We call this library the stochastic hyperfine interactions modeling library (SHIML). It provides routines written in the C programming language that (1) read a text description of a model for fluctuating hyperfine fields, (2) set up the Blume matrix, upon which the evolution operator of the system depends, and (3) find the eigenvalues and eigenvectors of the Blume matrix so that theoretical spectra of experimental hyperfine interaction measurements can be calculated. Example model calculations are included in the SHIML package to illustrate its use and to generate perturbed angular correlation spectra for the special case of polycrystalline samples when anisotropy terms of higher order than A22 can be neglected.

  14. Atmospheric-wake vortex interactions

    NASA Technical Reports Server (NTRS)

    Bilanin, A. J.; Hirsh, J. E.; Teske, M. E.; Hecht, A. M.

    1978-01-01

    The interactions of a vortex wake with a turbulent stratified atmosphere are investigated with the computer code WAKE. It is shown that atmospheric shear, turbulence, and stratification can provide the dominant mechanisms by which vortex wakes decay. Computations included the interaction of a vortex wake with a viscous ground plane. The observed phenomenon of vortex bounce is explained in terms of secondary vorticity produced on the ground. This vorticity is swept off the ground and advected about the vortex pair, thereby altering the classic hyperbolic trajectory. The phenomenon of the solitary vortex is explained as an interaction of a vortex with crosswind shear. Here, the vortex having the sign opposite that of the sign of the vorticity in the shear is dispersed by a convective instability. This instability results in the rapid production of turbulence which in turn disperses the smoke marking the vortex.

  15. Stacking interactions and DNA intercalation

    SciTech Connect

    Li, Dr. Shen; Cooper, Valentino R; Thonhauser, Prof. Timo; Lundqvist, Prof. Bengt I.; Langreth, David C.

    2009-01-01

    The relationship between stacking interactions and the intercalation of proflavine and ellipticine within DNA is investigated using a nonempirical van der Waals density functional for the correlation energy. Our results, employing a binary stack model, highlight fundamental, qualitative differences between base-pair base-pair interactions and that of the stacked intercalator base pair system. Most notable result is the paucity of torque which so distinctively defines the Twist of DNA. Surprisingly, this model, when combined with a constraint on the twist of the surrounding base-pair steps to match the observed unwinding of the sugar-phosphate backbone, was sufficient for explaining the experimentally observed proflavine intercalator configuration. Our extensive mapping of the potential energy surface of base-pair intercalator interactions can provide valuable information for future nonempirical studies of DNA intercalation dynamics.

  16. Dispersive interactions in graphitic nanostructures

    NASA Astrophysics Data System (ADS)

    Woods, L. M.; Popescu, A.; Drosdoff, D.; Bondarev, I. V.

    2013-02-01

    The Casimir interaction between graphitic nanostructures, such as carbon nanotubes and graphene sheets, is investigated at the quantum mechanical limit (T = 0 K) using a quantum electrodynamical approach for absorbing and dispersive media. It is found that the nanotube/nanotube interaction in a double wall carbon nanotube configuration is profoundly affected by the collective low frequency excitations of individual nanotubes. It is shown that pronounced, low frequency peaks in the nanotube electron energy loss spectra are a main factor contributing to the strength of the intertube attraction. The graphene/graphene force is also investigated. It is obtained that the graphene optical transparency is the main reason for the reduced attraction as compared to the one for perfect metals. This study presents a unified approach for electromagnetic interactions in graphitic nanostructures, which is able to account for their unique electronic and response properties and geometry configurations.

  17. Interactional Feedback in Naturalistic Interaction between L2 English Learners

    ERIC Educational Resources Information Center

    Ranaweera, Mahishi

    2015-01-01

    Theoretical and empirical data support that the feedback given in small group activities promote second language acquisition. There are many studies that have examined the impact of interaction on second language acquisition in controlled language situations. This study examines the small group activity "conversation partner" in order to…

  18. PCorral--interactive mining of protein interactions from MEDLINE.

    PubMed

    Li, Chen; Jimeno-Yepes, Antonio; Arregui, Miguel; Kirsch, Harald; Rebholz-Schuhmann, Dietrich

    2013-01-01

    The extraction of information from the scientific literature is a complex task-for researchers doing manual curation and for automatic text processing solutions. The identification of protein-protein interactions (PPIs) requires the extraction of protein named entities and their relations. Semi-automatic interactive support is one approach to combine both solutions for efficient working processes to generate reliable database content. In principle, the extraction of PPIs can be achieved with different methods that can be combined to deliver high precision and/or high recall results in different combinations at the same time. Interactive use can be achieved, if the analytical methods are fast enough to process the retrieved documents. PCorral provides interactive mining of PPIs from the scientific literature allowing curators to skim MEDLINE for PPIs at low overheads. The keyword query to PCorral steers the selection of documents, and the subsequent text analysis generates high recall and high precision results for the curator. The underlying components of PCorral process the documents on-the-fly and are available, as well, as web service from the Whatizit infrastructure. The human interface summarizes the identified PPI results, and the involved entities are linked to relevant resources and databases. Altogether, PCorral serves curator at both the beginning and the end of the curation workflow for information retrieval and information extraction. Database URL: http://www.ebi.ac.uk/Rebholz-srv/pcorral.

  19. Interactive Whiteboards: Do Teachers Really Use Them Interactively?

    ERIC Educational Resources Information Center

    Tatli, Cemal; Kiliç, Eylem

    2016-01-01

    The aim of this quantitative study is to examine high school teachers' use of specific features of interactive whiteboards (IWBs). During the 2012-2013 academic school year, 535 teachers in pilot schools from 10 provinces under the FATIH Project (Movement of Enhancing Opportunities and Improving Technology) participated. Data were collected…

  20. Light and noise pollution interact to disrupt interspecific interactions.

    PubMed

    McMahon, Taegan A; Rohr, Jason R; Bernal, Ximena E

    2017-02-07

    Studies on the consequences of urbanization often examine the effects of light, noise, and heat pollution independently on isolated species providing a limited understanding of how these combined stressors affect species interactions. Here, we investigate how these factors interact to affect parasitic frog-biting midges (Corethrella spp.) and their túngara frog (Engystomops pustulosus) hosts. A survey of túngara frog calling sites revealed that frog abundance was not significantly correlated with urbanization, light, noise, or temperature. In contrast, frog-biting midges were sensitive to light pollution and noise pollution. Increased light intensity significantly reduced midge abundance at low noise levels. At high noise intensity, there were no midges regardless of light level. Two field experiments controlling light and noise levels to examine attraction of the midges to their host and their feeding behavior confirmed the causality of these field patterns. These findings demonstrate that both light and noise pollution disrupt this host-parasite interaction and highlight the importance of considering interactions among species and types of pollutants to accurately assess the impacts of urbanization on ecological communities. This article is protected by copyright. All rights reserved.

  1. Interactive Whiteboards: Do Teachers Really Use Them Interactively?

    ERIC Educational Resources Information Center

    Tatli, Cemal; Kiliç, Eylem

    2016-01-01

    The aim of this quantitative study is to examine high school teachers' use of specific features of interactive whiteboards (IWBs). During the 2012-2013 academic school year, 535 teachers in pilot schools from 10 provinces under the FATIH Project (Movement of Enhancing Opportunities and Improving Technology) participated. Data were collected…

  2. Participant Interaction in Asynchronous Learning Environments: Evaluating Interaction Analysis Methods

    ERIC Educational Resources Information Center

    Blanchette, Judith

    2012-01-01

    The purpose of this empirical study was to determine the extent to which three different objective analytical methods--sequence analysis, surface cohesion analysis, and lexical cohesion analysis--can most accurately identify specific characteristics of online interaction. Statistically significant differences were found in all points of…

  3. Adolescent girls' parasocial interactions with media figures.

    PubMed

    Theran, Sally A; Newberg, Emily M; Gleason, Tracy R

    2010-01-01

    We examined aspects of adolescent girls' parasocial interactions in the context of typical development. Parasocial interactions are defined as symbolic, one-sided quasi-interactions between a viewer and a media figure. In total, 107 adolescent girls were examined; 94% reported engaging in parasocial interactions to some degree. Preoccupied attachment style predicted the degree of involvement in and emotional intensity of parasocial interactions. Results suggest that parasocial interactions are characteristic of girls with preoccupied attachment, but are also part of normative development.

  4. Topology of molecular interaction networks

    PubMed Central

    2013-01-01

    Molecular interactions are often represented as network models which have become the common language of many areas of biology. Graphs serve as convenient mathematical representations of network models and have themselves become objects of study. Their topology has been intensively researched over the last decade after evidence was found that they share underlying design principles with many other types of networks. Initial studies suggested that molecular interaction network topology is related to biological function and evolution. However, further whole-network analyses did not lead to a unified view on what this relation may look like, with conclusions highly dependent on the type of molecular interactions considered and the metrics used to study them. It is unclear whether global network topology drives function, as suggested by some researchers, or whether it is simply a byproduct of evolution or even an artefact of representing complex molecular interaction networks as graphs. Nevertheless, network biology has progressed significantly over the last years. We review the literature, focusing on two major developments. First, realizing that molecular interaction networks can be naturally decomposed into subsystems (such as modules and pathways), topology is increasingly studied locally rather than globally. Second, there is a move from a descriptive approach to a predictive one: rather than correlating biological network topology to generic properties such as robustness, it is used to predict specific functions or phenotypes. Taken together, this change in focus from globally descriptive to locally predictive points to new avenues of research. In particular, multi-scale approaches are developments promising to drive the study of molecular interaction networks further. PMID:24041013

  5. Anesthetics interacting with lipid rafts.

    PubMed

    Bandeiras, Cátia; Serro, Ana Paula; Luzyanin, Konstantin; Fernandes, Anabela; Saramago, Benilde

    2013-01-23

    The exact mechanism by which anesthetics induce cell membrane-mediated modifications is still an open question. Although the fluidization effect of the anesthetic molecules on the cellular membrane is widely recognized, it is not known if anesthetics show any preference for specific membrane domains, namely the lipid rafts. The importance of these membrane micro-domains derives from the fact that they have been associated with cell signaling pathways, as well as with specific drug interactions. The objective of this work is to contribute for the elucidation of this question through the comparison of the anesthetic interactions with membranes of various lipid compositions. Liposomes prepared with an equimolar mixture of POPC, sphingomyelin and cholesterol, were chosen as models for lipid rafts. The interactions of these liposomes with two local anesthetics, tetracaine and lidocaine, and one general anesthetic, propofol, were studied. The effect of cholesterol was investigated by comparing anesthetic interactions with POPC/SM liposomes and POPC/SM/CHOL liposomes. The following experimental techniques were used: quartz crystal microbalance with dissipation, differential scanning calorimetry and phosphorus nuclear magnetic resonance. Although the liposomes investigated by the different techniques are not in the same conditions, it is possible to assemble the information obtained from all experimental techniques employed to reach a general conclusion. Tetracaine interacts more with raftlike domains, lidocaine induces stronger modifications on POPC/SM liposomes and the results for propofol are not fully conclusive but it seems to be the least prone to lipid interactions. The results were compared with those obtained with DMPC-containing liposomes, reported in a previous work.

  6. Cosmology and the weak interaction

    NASA Technical Reports Server (NTRS)

    Schramm, David N.

    1989-01-01

    The weak interaction plays a critical role in modern Big Bang cosmology. Two of its most publicized comological connections are emphasized: big bang nucleosynthesis and dark matter. The first of these is connected to the cosmological prediction of neutrine flavors, N(sub nu) is approximately 3 which in now being confirmed. The second is interrelated to the whole problem of galacty and structure formation in the universe. The role of the weak interaction both for dark matter candidates and for the problem of generating seeds to form structure is demonstrated.

  7. Cosmology and the weak interaction

    SciTech Connect

    Schramm, D.N. ):)

    1989-12-01

    The weak interaction plays a critical role in modern Big Bang cosmology. This review will emphasize two of its most publicized cosmological connections: Big Bang nucleosynthesis and Dark Matter. The first of these is connected to the cosmological prediction of Neutrino Flavours, N{sub {nu}} {approximately} 3 which is now being confirmed at SLC and LEP. The second is interrelated to the whole problem of galaxy and structure formation in the universe. This review will demonstrate the role of the weak interaction both for dark matter candidates and for the problem of generating seeds to form structure. 87 refs., 3 figs., 5 tabs.

  8. Radiative interactions in nonequilibrium flows

    NASA Technical Reports Server (NTRS)

    Tiwari, S. N.; Chandrasekhar, R.

    1992-01-01

    The influence of vibrational and chemical nonequilibrium upon infrared radiative energy transfer in nonisothermal gases is investigated. Essential information is provided on rate equations, relaxation times, transfer equations, band absorption, and radiative flux equations. The methodology developed is applied to three specific cases. These are, absorbing-emitting species between isothermal parallel plates, radiating gases in the earth's atmosphere, and supersonic flow of premixed hydrogen and air in an expanding nozzle. The results obtained for different cases reveal that the extent of radiative interactions is reduced significantly under nonequilibrium conditions. The method developed can be easily extended to investigate radiative interactions in complex nonequilibrium flows.

  9. Elementary Particles and Weak Interactions

    DOE R&D Accomplishments Database

    Lee, T. D.; Yang, C. N.

    1957-01-01

    Some general patterns of interactions between various elementary particles are reviewed and some general questions concerning the symmetry properties of these particles are studied. Topics are included on the theta-tau puzzle, experimental limits on the validity of parity conservation, some general discussions on the consequences due to possible non-invariance under P, C, and T, various possible experimental tests on invariance under P, C, and T, a two-component theory of the neutrino, a possible law of conservation of leptons and the universal Fermi interactions, and time reversal invariance and Mach's principle. (M.H.R.)

  10. Interactive real time flow simulations

    NASA Technical Reports Server (NTRS)

    Sadrehaghighi, I.; Tiwari, S. N.

    1990-01-01

    An interactive real time flow simulation technique is developed for an unsteady channel flow. A finite-volume algorithm in conjunction with a Runge-Kutta time stepping scheme was developed for two-dimensional Euler equations. A global time step was used to accelerate convergence of steady-state calculations. A raster image generation routine was developed for high speed image transmission which allows the user to have direct interaction with the solution development. In addition to theory and results, the hardware and software requirements are discussed.

  11. Macrophage Cryptococcus interactions: an update

    PubMed Central

    Mansour, Michael K.; Reedy, Jennifer L.; Tam, Jenny M.; Vyas, Jatin M.

    2014-01-01

    Cryptococcus species are fungal pathogens that are a leading cause of mortality. Initial inoculation is through the pulmonary route and, if disseminated, results in severe invasive infection including meningoencephalitis. Macrophages are the dominant phagocytic cell that interacts with Cryptococcus. Emerging theories suggest that Cryptococcus microevolution in macrophages is linked to survival and virulence within the host. In addition, Cryptococcus elaborates virulence factors as well as usurps host machinery to establish macrophage activation states that are permissive to intracellular survival and replication. In this review, we provide an update of the recent findings pertaining to macrophage interaction with Cryptococcus and focus on new avenues for biomedical research. PMID:24660045

  12. Connecting interacting galaxies with manifolds

    NASA Astrophysics Data System (ADS)

    Romero-Gomez, M.; Athanassoula, E.

    2017-03-01

    It is well known that the interaction between two disk galaxies generates tidal spiral arms and a connection in the form of a bridge. Here we address the question of the formation of tidal arms and bridges from a dynamical point of view. We model the bridges and tails observed in interacting galaxies using the invariant manifolds associated to the Lyapunov orbits of the Lagrangian points of the galactic system, when the two galaxies are considered as two point masses in a circular orbit.

  13. Learning in interactive science centres

    NASA Astrophysics Data System (ADS)

    Beiers, Robin; McRobbie, Cam

    1992-12-01

    The potential of informal sources of science learning to supplement and interact with formal classroom science is receiving increasing recognition and attention in the research literature. In this study, a phenomenographic approach was used to determine changes in levels of understanding of 27 grade 7 primary school children as a result of a visit to an interactive science centre. The results showed that most students did change their levels of understanding of aspects of the concept “sound”. The study also provides information which will be of assistance to teachers on the levels of understanding displayed by students on this concept.

  14. Interactions of neutrinos with matter

    NASA Astrophysics Data System (ADS)

    Vannucci, F.

    2017-07-01

    Neutrinos are elementary particles electrically neutral which belong to the family of leptons. As a consequence and in first approximation they only undergo weak processes. This gives them very special properties. They are ideal tools to study precisely the weak interactions, but there is a price to pay: neutrinos are characterized by extremely low probabilities of interactions, they easily penetrate large amount of matter without being stopped. Consequently, it is hard to perform neutrino physics measurements. In practice the difficulty is twofold: in order to accumulate enough statistics, experiments must rely on huge fluxes traversing huge detectors, the number of interactions being obviously proportional to these two factors. As a corollary, backgrounds are difficult to handle because they appear much more commonly than good events. Nevertheless, neutrino interactions have been detected from a variety of sources, both man-made and natural, from very low to very large energies. The aim of this review is to survey our current knowledge about interaction cross sections of neutrinos with matter across all pertinent energy scales. We will see that neutrino interactions cover a large range of processes: nuclear capture, inverse beta-decay, quasi-elastic scattering, resonant pion production, deep inelastic scattering and ultra-high energy interactions. All the gathered information will be used to study weak properties of matter but it will also allow to explore the properties of the neutrinos themselves. In particular, the known three different flavors of neutrinos have different behaviors inside matter and this will be relevant to give some precious understanding about their intrinsic parameters in particular their masses and mixings. As a second order process, neutrinos can undergo electromagnetic interactions. This will also be discussed. Although the corresponding phenomena are not yet experimentally proven by actual measurements, the theory is able to calculate

  15. Multi-shell effective interactions

    NASA Astrophysics Data System (ADS)

    Tsunoda, Naofumi; Takayanagi, Kazuo; Hjorth-Jensen, Morten; Otsuka, Takaharu

    2014-02-01

    Background: Effective interactions, either derived from microscopic theories or based on fitting selected properties of nuclei in specific mass regions, are widely used inputs to shell-model studies of nuclei. The commonly used unperturbed basis functions are given by the harmonic oscillator. Until recently, most shell-model calculations have been confined to a single oscillator shell like the sd shell or the pf shell. Recent interest in nuclei away from the stability line requires, however, larger shell-model spaces. Because the derivation of microscopic effective interactions has been limited to degenerate models spaces, there are both conceptual and practical limits to present shell-model calculations that utilize such interactions. Purpose: The aim of this work is to present a novel microscopic method to calculate effective nucleon-nucleon interactions for the nuclear shell model. Its main difference from existing theories is that it can be applied not only to degenerate model spaces but also to nondegenerate model spaces. This has important consequences, in particular for intershell matrix elements of effective interactions. Methods: The formalism is presented in the form of a many-body perturbation theory based on the recently developed extended Kuo-Krenciglowa method. Our method enables us to microscopically construct effective interactions not only in one oscillator shell but also for several oscillator shells. Results: We present numerical results using effective interactions within (i) a single oscillator shell (a so-called degenerate model space) like the sd shell or the pf shell and (ii) two major shells (nondegenerate model space) like the sdf7p3 shell or the pfg9 shell. We also present energy levels of several nuclei that have two valence nucleons on top of a given closed-shell core. Conclusions: Our results show that the present method works excellently in shell-model spaces that comprise several oscillator shells, as well as in a single oscillator

  16. Interaction of two dielectric macroparticles

    SciTech Connect

    Munirov, V. R.; Filippov, A. V.

    2013-11-15

    The electrostatic interaction of two charged dielectric spherical particles with a nonuniform freecharge distribution over their surfaces in an external homogeneous electric field is considered. An exact solution for the electric field potential is obtained, and an analytical expression for the interaction force between these two particles is found. The case of a uniform free-charge distribution is considered in detail, and the region of parameters in the plane “the ratio of the radii vs. the ratio of the charges,” where repulsion between two like-charged particles turns into attraction as the interparticle distance decreases is established.

  17. Models of dyadic social interaction.

    PubMed Central

    Griffin, Dale; Gonzalez, Richard

    2003-01-01

    We discuss the logic of research designs for dyadic interaction and present statistical models with parameters that are tied to psychologically relevant constructs. Building on Karl Pearson's classic nineteenth-century statistical analysis of within-organism similarity, we describe several approaches to indexing dyadic interdependence and provide graphical methods for visualizing dyadic data. We also describe several statistical and conceptual solutions to the 'levels of analytic' problem in analysing dyadic data. These analytic strategies allow the researcher to examine and measure psychological questions of interdependence and social influence. We provide illustrative data from casually interacting and romantic dyads. PMID:12689382

  18. IPLS: Interactive Pallet Loading System.

    DTIC Science & Technology

    1981-06-01

    AD-AI01 410 FLOR IDA UNIV GAINESVILLE DEPT OF INDUSTRIAL AND SYS--ETC F/6 15/5 IPLS. INTERACTIVE PALLET LOADING SYSTEM.(U) .JN 81 T J HODGSON. N0OCIA...76-C 0096 UNCLASSIFIEDRR69L * unuuuu L~EhEEEE / IPL SINTERACTIVE PALLET LOADING SYSTEM Research Report No. 8]-9 by Thorn J. Hodgson June, 1981...COVEREo IPLS: INTERACTIVE PALLET LOADING SyS Technical / j ’.l e P a t . | - f F O M IN G O R G . R E P O R T N U M B E R--81-9 7. AuTmo, .. s

  19. Generalized interaction-free evolutions

    NASA Astrophysics Data System (ADS)

    Militello, Benedetto; Chruściński, Dariusz; Messina, Antonino; NaleŻyty, Paweł; Napoli, Anna

    2016-02-01

    A thorough analysis of the evolutions of bipartite systems characterized by the "effective absence" of interaction between the two subsystems is reported. First, the connection between the concepts underlying interaction-free evolutions (IFE) and decoherence-free subspaces (DFS) is explored, showing intricate relations between these concepts. Second, starting from this analysis and inspired by a generalization of DFS already known in the literature, we introduce the notion of generalized IFE (GIFE), also providing a useful characterization that allows one to develop a general scheme for finding GIFE states.

  20. Dynamics of convective scale interaction

    NASA Technical Reports Server (NTRS)

    Purdom, James F. W.; Sinclair, Peter C.

    1988-01-01

    Several of the mesoscale dynamic and thermodynamic aspects of convective scale interaction are examined. An explanation of how sounding data can be coupled with satellite observed cumulus development in the warm sector and the arc cloud line's time evolution to develop a short range forecast of expected convective intensity along an arc cloud line. The formative, mature and dissipating stages of the arc cloud line life cycle are discussed. Specific properties of convective scale interaction are presented and the relationship between arc cloud lines and tornado producing thunderstorms is considered.

  1. Interaction of caldesmon with phospholipids.

    PubMed Central

    Czuryło, E A; Zborowski, J; Dabrowska, R

    1993-01-01

    The interaction of caldesmon with liposomes composed of various phospholipids has been examined by tryptophan fluorescence spectroscopy. The results indicate that caldesmon makes its strongest complex with phosphatidylserine (PS) vesicles (Kass. = 1.45 x 10(5) M-1). Both electrostatic and hydrophobic interactions contribute to the stability of this complex. The site for strong binding of PS seems to be located in the N-terminal part of the 34 kDa C-terminal fragment of caldesmon. Binding of PS at this site results in displacement of calmodulin from its complex with caldesmon. Images Figure 4 PMID:8484721

  2. Dynamics of convective scale interaction

    NASA Technical Reports Server (NTRS)

    Purdom, James F. W.; Sinclair, Peter C.

    1988-01-01

    Several of the mesoscale dynamic and thermodynamic aspects of convective scale interaction are examined. An explanation of how sounding data can be coupled with satellite observed cumulus development in the warm sector and the arc cloud line's time evolution to develop a short range forecast of expected convective intensity along an arc cloud line. The formative, mature and dissipating stages of the arc cloud line life cycle are discussed. Specific properties of convective scale interaction are presented and the relationship between arc cloud lines and tornado producing thunderstorms is considered.

  3. Orbital, Rotational, and Climatic Interactions

    NASA Technical Reports Server (NTRS)

    Bills, Bruce G. (Editor)

    1992-01-01

    The report of an international meeting on the topic of Orbital, Rotational, and Climatic Interactions, which was held 9-11 Jul. 1991 at the Johns Hopkins University is presented. The meeting was attended by 22 researchers working on various aspects of orbital and rotational dynamics, paleoclimate data analysis and modeling, solid-Earth deformation studies, and paleomagnetic analyses. The primary objective of the workshop was to arrive at a better understanding of the interactions between the orbital, rotational, and climatic variations of the Earth. This report contains a brief introduction and 14 contributed papers which cover most of the topics discussed at the meeting.

  4. Climate Change and Disturbance Interactions

    NASA Astrophysics Data System (ADS)

    McKenzie, Don; Allen, Craig D.

    2007-05-01

    Workshop on Climate Change and Disturbance Interactions in Western North America, Tucson, Ariz., 12-15 February 2007 Warming temperatures across western North America, coupled with increased drought, are expected to exacerbate disturbance regimes, particularly wildfires, insect outbreaks, and invasions of exotic species. Many ecologists and resource managers expect ecosystems to change more rapidly from disturbance effects than from the effects of a changing climate by itself. A particular challenge is to understand the interactions among disturbance regimes; for example, how will massive outbreaks of bark beetles, which kill drought-stressed trees by feeding on cambial tissues, increase the potential for large severe wildfires in a warming climate?

  5. Exaggerated Claims for Interactive Stories

    NASA Astrophysics Data System (ADS)

    Thue, David; Bulitko, Vadim; Spetch, Marcia; Webb, Michael

    As advertising becomes more crucial to video games' success, developers risk promoting their products beyond the features that they can actually include. For features of interactive storytelling, the effects of making such exaggerations are not well known, as reports from industry have been anecdotal at best. In this paper, we explore the effects of making exaggerated claims for interactive stories, in the context of the theory of advertising. Results from a human user study show that female players find linear and branching stories to be significantly less enjoyable when they are advertised with exaggerated claims.

  6. Interaction Mindsets, Interactional Behaviors, and L2 Development: An Affective-Social-Cognitive Model

    ERIC Educational Resources Information Center

    Sato, Masatoshi

    2017-01-01

    This classroom-based study explored links among second language (L2) learners' interaction mindsets, interactional behaviors, and L2 development in the context of peer interaction. While peer interaction research has revealed that certain interactional behaviors (e.g., receiving corrective feedback and engaging in collaborative interaction) assist…

  7. Activities for an Interactive Classroom.

    ERIC Educational Resources Information Center

    Golub, Jeffrey N.

    Focusing particularly on student writing, this book describes the principles of an interactive classroom and presents specific activities which adhere to those principles. Acknowledging that such classrooms require that the students feel comfortable with each other, the book details several activities that help to build a positive classroom…

  8. Interactive Television and Distance Learning.

    ERIC Educational Resources Information Center

    Rees, Fred J.; Downs, Dennis A.

    1995-01-01

    Describes the origins and operations of the Iowa Communications Network, an interactive distance learning program. Presents several examples of how the network can benefit music educators in college and K-12 institutions. Maintains that the system can be a model for similar distance music education networks. (CFR)

  9. Magnetoelastic interactions in bubble materials

    NASA Astrophysics Data System (ADS)

    Szymczak, H.

    1980-01-01

    Recent theoretical and experimental investigations of magnetoelastic phenomena in bubble materials (garnet and amorphous thin films) are presented. An attempt is made to describe these problems within the framework of group theory. Moreover, several microscopic models of magnetoelastic interactions in bubble materials is presented.

  10. JSC interactive basic accounting system

    NASA Technical Reports Server (NTRS)

    Spitzer, J. F.

    1978-01-01

    Design concepts for an interactive basic accounting system (IBAS) are considered in terms of selecting the design option which provides the best response at the lowest cost. Modeling the IBAS workload and applying this workload to a U1108 EXEC 8 based system using both a simulation model and the real system is discussed.

  11. Interactive Whiteboards in Japanese Education

    ERIC Educational Resources Information Center

    Liversidge, Gordon

    2013-01-01

    The use of interactive whiteboards (IWBs) is widespread in the United Kingdom, Australia, and to some extent in the United States and Canada. However, this potentially learning enhancing technology has been adopted very little in Japan at any level of education, apart from some international schools. Furthermore, one of the world's two leading IWB…

  12. Suicidal Behavior and Marital Interaction.

    ERIC Educational Resources Information Center

    Berman, Alan L.; And Others

    1992-01-01

    Presents two cases chosen to draw attention to marital and developmental dynamics of suicidal behavior. Both case vignettes are based on individual interviews with suicidal persons and their spouses during the suicidal person's psychiatric hospitalization, and both include observations of the marital interaction. Case vignettes are followed by…

  13. Biomolecular interactions: essential instrumentation methods.

    PubMed

    Messina, Paula Veronica; Ruso, Juan Manuel

    2013-01-01

    The main goal of this review is to outline the basic principles and applications of the broad range of modern biophysical technical methods used to study the different aspects of protein–ligand interactions by discussing such aspects as newer systems, unusual approaches and highly used techniques.

  14. Strong WW Interaction at LHC

    SciTech Connect

    Pelaez, Jose R

    1998-12-14

    We present a brief pedagogical introduction to the Effective Electroweak Chiral Lagrangians, which provide a model independent description of the WW interactions in the strong regime. When it is complemented with some unitarization or a dispersive approach, this formalism allows the study of the general strong scenario expected at the LHC, including resonances.

  15. Students and the Interactive Whiteboard

    ERIC Educational Resources Information Center

    Biró, Piroska

    2011-01-01

    The spread of Interactive Whiteboards in Hungary has made students more curious, interested and motivated. The new digital generation claims reform and besides the traditional education they need digital material, extra knowledge since it is much easier to access extra information in connection with a particular curriculum. They spend a lot of…

  16. Inelastic final-state interaction

    SciTech Connect

    Suzuki, Mahiko

    2008-03-01

    The final-state interaction in multichannel decay processes is systematically studied in the hadronic picture with application to B decay in mind. Since the final-state interaction is intrinsically interwoven with the decay interaction in this case, no simple phase theorem like ''Watson's theorem'' holds for experimentally observed final states. We first solve exactly the two-channel problem as a toy model in order to clarify the issues. The constraints of the two-channel approximation turns out to be too stringent for most B decay modes, but realistic multichannel problems are too complex for useful quantitative analysis at present. To alleviate the stringent constraints of the two-body problem and to cope with complexity beyond it, we introduce a method of approximation that is applicable to the case where one prominent inelastic channel dominates over all others. We illustrate this approximation method with the amplitude of the decay B{yields}K{pi} fed by the intermediate states of a charmed-meson pair. Even with our approximation we need more accurate information of strong interactions than we have now. Nonetheless we are able to obtain some insight in the issue and draw useful conclusions on general features on the strong phases.

  17. Inelastic final-state interaction

    NASA Astrophysics Data System (ADS)

    Suzuki, Mahiko

    2008-03-01

    The final-state interaction in multichannel decay processes is systematically studied in the hadronic picture with application to B decay in mind. Since the final-state interaction is intrinsically interwoven with the decay interaction in this case, no simple phase theorem like “Watson’s theorem” holds for experimentally observed final states. We first solve exactly the two-channel problem as a toy model in order to clarify the issues. The constraints of the two-channel approximation turns out to be too stringent for most B decay modes, but realistic multichannel problems are too complex for useful quantitative analysis at present. To alleviate the stringent constraints of the two-body problem and to cope with complexity beyond it, we introduce a method of approximation that is applicable to the case where one prominent inelastic channel dominates over all others. We illustrate this approximation method with the amplitude of the decay B→Kπ fed by the intermediate states of a charmed-meson pair. Even with our approximation we need more accurate information of strong interactions than we have now. Nonetheless we are able to obtain some insight in the issue and draw useful conclusions on general features on the strong phases.

  18. Early Mother-Child Interaction.

    ERIC Educational Resources Information Center

    d'Agostino, Micheline

    1986-01-01

    This journal issue presents an overview of mother-child interaction during the first year of the child's life. Contents of the first section, which concern the development of the mother-child relationship, focus on the concept of the maternal instinct, mother and child during intrauterine life, birth of the child, the postnatal period (including…

  19. TIGER: Turbomachinery interactive grid generation

    NASA Technical Reports Server (NTRS)

    Soni, Bharat K.; Shih, Ming-Hsin; Janus, J. Mark

    1992-01-01

    A three dimensional, interactive grid generation code, TIGER, is being developed for analysis of flows around ducted or unducted propellers. TIGER is a customized grid generator that combines new technology with methods from general grid generation codes. The code generates multiple block, structured grids around multiple blade rows with a hub and shroud for either C grid or H grid topologies. The code is intended for use with a Euler/Navier-Stokes solver also being developed, but is general enough for use with other flow solvers. TIGER features a silicon graphics interactive graphics environment that displays a pop-up window, graphics window, and text window. The geometry is read as a discrete set of points with options for several industrial standard formats and NASA standard formats. Various splines are available for defining the surface geometries. Grid generation is done either interactively or through a batch mode operation using history files from a previously generated grid. The batch mode operation can be done either with a graphical display of the interactive session or with no graphics so that the code can be run on another computer system. Run time can be significantly reduced by running on a Cray-YMP.

  20. Interaction of Radiation with Matter

    SciTech Connect

    Rickards, J.

    2010-09-10

    A flash introductory course in the interaction of ionizing radiation with matter is presented for students starting out in nuclear physics, medical applications of radiation, materials modification, radiation damage, detectors, materials analysis, radiation protection, and other applications. Emphasis is on defining basic concepts and on a simple visualization of ideas for practical applications, rather than on completeness or rigor.

  1. Affect Control in International Interactions

    ERIC Educational Resources Information Center

    Heise, David R.; Lerner, Steven J.

    2006-01-01

    This research tests the proposition that national leaders generate international interactions in the process of maintaining sentiments about nations and international actions. The analysis deals with 1,934 international incidents in which one of 25 Middle Eastern nations responded twice within four weeks to an instigation by another of the 25…

  2. Predicting Deviancy in Family Interaction.

    ERIC Educational Resources Information Center

    Karpowitz, Dennis H.

    Should a stimulus be defined as the single event immediately preceding a response (simple stimulus) or as a constellation of antecedents representing several preceding events (complex stimulus)? Sixty-eight families with a child between four and eight years of age were observed, and family interactions coded in the naturalistic setting of the…

  3. Interactive Cable Television. Final Report.

    ERIC Educational Resources Information Center

    Active Learning Systems, Inc., Minneapolis, MN.

    This report describes an interactive video system developed by Active Learning Systems which utilizes a cable television (TV) network as its delivery system to transmit computer literacy lessons to high school and college students. The system consists of an IBM PC, Pioneer LDV 4000 videodisc player, and Whitney Supercircuit set up at the head end…

  4. Grid Interaction Technical Team Roadmap

    SciTech Connect

    2013-06-01

    The mission of the Grid Interaction Technical Team (GITT) is to support a transition scenario to large scale grid-connected vehicle charging with transformational technology, proof of concept and information dissemination. The GITT facilitates technical coordination and collaboration between vehicle-grid connectivity and communication activities among U.S. DRIVE government and industry partners.

  5. Interactive publications: creation and usage

    NASA Astrophysics Data System (ADS)

    Thoma, George R.; Ford, Glenn; Chung, Michael; Vasudevan, Kirankumar; Antani, Sameer

    2006-02-01

    As envisioned here, an "interactive publication" has similarities to multimedia documents that have been in existence for a decade or more, but possesses specific differentiating characteristics. In common usage, the latter refers to online entities that, in addition to text, consist of files of images and video clips residing separately in databases, rarely providing immediate context to the document text. While an interactive publication has many media objects as does the "traditional" multimedia document, it is a self-contained document, either as a single file with media files embedded within it, or as a "folder" containing tightly linked media files. The main characteristic that differentiates an interactive publication from a traditional multimedia document is that the reader would be able to reuse the media content for analysis and presentation, and to check the underlying data and possibly derive alternative conclusions leading, for example, to more in-depth peer reviews. We have created prototype publications containing paginated text and several media types encountered in the biomedical literature: 3D animations of anatomic structures; graphs, charts and tabular data; cell development images (video sequences); and clinical images such as CT, MRI and ultrasound in the DICOM format. This paper presents developments to date including: a tool to convert static tables or graphs into interactive entities, authoring procedures followed to create prototypes, and advantages and drawbacks of each of these platforms. It also outlines future work including meeting the challenge of network distribution for these large files.

  6. Congested Aggregation via Newtonian Interaction

    NASA Astrophysics Data System (ADS)

    Craig, Katy; Kim, Inwon; Yao, Yao

    2017-08-01

    We consider a congested aggregation model that describes the evolution of a density through the competing effects of nonlocal Newtonian attraction and a hard height constraint. This provides a counterpoint to existing literature on repulsive-attractive nonlocal interaction models, where the repulsive effects instead arise from an interaction kernel or the addition of diffusion. We formulate our model as the Wasserstein gradient flow of an interaction energy, with a penalization to enforce the constraint on the height of the density. From this perspective, the problem can be seen as a singular limit of the Keller-Segel equation with degenerate diffusion. Two key properties distinguish our problem from previous work on height constrained equations: nonconvexity of the interaction kernel (which places the model outside the scope of classical gradient flow theory) and nonlocal dependence of the velocity field on the density (which causes the problem to lack a comparison principle). To overcome these obstacles, we combine recent results on gradient flows of nonconvex energies with viscosity solution theory. We characterize the dynamics of patch solutions in terms of a Hele-Shaw type free boundary problem and, using this characterization, show that in two dimensions patch solutions converge to a characteristic function of a disk in the long-time limit, with an explicit rate on the decay of the energy. We believe that a key contribution of the present work is our blended approach, combining energy methods with viscosity solution theory.

  7. Inter-Action's Environmental Programmes.

    ERIC Educational Resources Information Center

    Knights, John

    1984-01-01

    Describes the work of Inter-Action, a voluntary organization funded to explore ways in which creative arts can be applied to the resolution of social and environmental problems of the inner-city. Environmental projects for neighborhood residents focus on city farms, community architecture, family food production, concrete sculptures, and…

  8. Electron spin from self interaction

    SciTech Connect

    Spavieri, G. |

    1992-06-01

    The author explores the possibility that the electron self-interaction is the origin of the spin and of the radiative effects of QED. The electron is conceived as a charged, massless, point particle with a quantum or stochastic, internal motion about its center of mass and bound by a self-interaction potential. The hydrodynamic equations of motion describing the electron in its center of mass frame are related to non-Markovian stochastic equations recently used to derive the Schroedinger equation. By averaging over this stochastic internal motion and identifying the energy with the rest mass energy, the angular momentum exhibits properties characteristic of spin. The electromagnetic self-interactions added to the Hamiltonian of the particle correct the g factor to yield the anomalous value (g{minus}2)/2 {approx} 1159.7(2.3) X 10{sup {minus}6} in agreement with experiment. Calculations of other {open_quotes}radiative{close_quotes} effects including the Lamb shift are presented. The results obtained are finite and suggest that the QED corrections attributed to radiative effects could be obtained classically, i.e., without second quantization and renormalization, by complementing the Dirac theory with this self-interaction mechanism. The g factor dependence on the external magnetic field of this and other spin models is compared with that of QED, showing that these theories can be tested by the present precision measurements of the g factor. 33 refs., 2 tabs.

  9. Interactive Multimedia: Practice and Promise.

    ERIC Educational Resources Information Center

    Latchem, Colin, Ed.; And Others

    This book describes developments in interactive multimedia (IMM) in the early 1990s. Its aim is to provide educators, students, trainers, librarians, managers, and practitioners with an overview, not only of the directions and uses of the technology, but also of the research foundations and educational and contextual issues that need to be…

  10. Weak interaction physics at ISOLDE

    NASA Astrophysics Data System (ADS)

    Severijns, N.; Blank, B.

    2017-07-01

    Radioactive nuclei offer unique possibilities to study the structure and symmetries of the weak interaction in nuclear β decay. The large variety of nuclear states available allows selecting the ones that are best suited to study the phenomena of interest with optimal sensitivity, while at the same time minimising the effects of nuclear structure. The ISOLDE facility, offering worldwide the largest variety and intensity of radioactive beams, is one of the best suited laboratories in this respect. Over the last decade or so different aspects of the weak interaction have been studied at ISOLDE, ranging from half-lives, branching ratios and nuclear masses relevant for the determination of the V ud quark-mixing matrix element, over β-asymmetry and β ν correlation measurements searching for possible tensor and/or scalar contributions to the weak interaction, up to a measurement showing the effect of parity violation in the weak interaction in gamma decay. In addition, new projects respectively searching for scalar currents in the β-delayed proton decay of 32Ar, or to determine the V ud quark-mixing matrix element from the β-asymmetry parameter in the mirror decay of 35Ar, have just started.

  11. Demonstration of Data Interactive Publications

    NASA Astrophysics Data System (ADS)

    Domenico, B.; Weber, J.

    2012-04-01

    This is a demonstration version of the talk given in session ESSI2.4 "Full lifecycle of data." For some years now, the authors have developed examples of online documents that allowed the reader to interact directly with datasets, but there were limitations that restricted the interaction to specific desktop analysis and display tools that were not generally available to all readers of the documents. Recent advances in web service technology and related standards are making it possible to develop systems for publishing online documents that enable readers to access, analyze, and display the data discussed in the publication from the perspective and in the manner from which the author wants it to be represented. By clicking on embedded links, the reader accesses not only the usual textual information in a publication, but also data residing on a local or remote web server as well as a set of processing tools for analyzing and displaying the data. With the option of having the analysis and display processing provided on the server (or in the cloud), there are now a broader set of possibilities on the client side where the reader can interact with the data via a thin web client, a rich desktop application, or a mobile platform "app." The presentation will outline the architecture of data interactive publications along with illustrative examples.

  12. Nonverbal Behavior in Tutoring Interactions.

    ERIC Educational Resources Information Center

    Feldman, Robert S.

    This document reports on a series of studies carried out concerning nonverbal behavior in peer tutoring interactions. The first study examined the encoding (enactment) of nonverbal behavior in a tutoring situation. Results clearly indicated that the tutor's nonverbal behavior was affected by the performance of the tutee. The question of whether or…

  13. Learning with Interactive Graphical Representations.

    ERIC Educational Resources Information Center

    Saljo, Roger, Ed.

    1999-01-01

    The seven articles of this theme issue deal with the use of computer-based interactive graphical representations. Studying their use will bring answers to users of static graphics in traditional paper-based media and those who plan instruction using graphical representations that allow semantically direct manipulation. (SLD)

  14. Modeling Interactions in Small Groups

    ERIC Educational Resources Information Center

    Heise, David R.

    2013-01-01

    A new theory of interaction within small groups posits that group members initiate actions when tension mounts between the affective meanings of their situational identities and impressions produced by recent events. Actors choose partners and behaviors so as to reduce the tensions. A computer model based on this theory, incorporating reciprocal…

  15. Social Interactions in Online Gaming

    ERIC Educational Resources Information Center

    Griffiths, Mark; Hussain, Zaheer; Grüsser, Sabine M.; Thalemann, Ralf; Cole, Helena; Davies, Mark N. O.; Chappell, Darren

    2011-01-01

    This paper briefly overviews five studies examining massively multiplayer online role-playing games (MMORPGs). The first study surveyed 540 gamers and showed that the social aspects of the game were the most important factor for many gamers. The second study explored the social interactions of 912 MMORPG players and showed they created strong…

  16. [Drug interactions and the elderly].

    PubMed

    Le Jeunne, C; Hugues, F C

    1995-01-01

    Elderly people are particularly at risk for drug interactions, for several reasons. They are the part of the population who consume the most drugs: over 75 years the mean number of drugs on a prescription is 5.6. As they suffer from various associated diseases, they see several medical specialists, each of them adding a new prescription to the others. Self-prescriptions complicate the problem because they are rarely mentioned. Changes in pharmacokinetics in the elderly tend to increase blood concentrations of drugs. Elderly people suffer from altered homeostatic mechanisms to compensate for adverse drug effects. As a whole, such individuals are more exposed to the side effects of drugs. The drugs most often involved in these interactions are diuretics, non-steroidal anti-inflammatory drugs, benzodiazepines, antiarrhythmics, cardiac glycosides, antihypertensive drugs, oral antidiabetics and antalgics. The clinical accidents most often occurring with these drug interactions are: malaise, orthostatic hypotension, loss of conciousness, amnesia, confusion, renal insufficiency, digestive problems. Since elderly people are less likely to recover easily, this problem of drug interaction should be looked for systematically.

  17. Social Interactions in Online Gaming

    ERIC Educational Resources Information Center

    Griffiths, Mark; Hussain, Zaheer; Grüsser, Sabine M.; Thalemann, Ralf; Cole, Helena; Davies, Mark N. O.; Chappell, Darren

    2011-01-01

    This paper briefly overviews five studies examining massively multiplayer online role-playing games (MMORPGs). The first study surveyed 540 gamers and showed that the social aspects of the game were the most important factor for many gamers. The second study explored the social interactions of 912 MMORPG players and showed they created strong…

  18. Increasing Positive Interactive Classroom Behavior.

    ERIC Educational Resources Information Center

    Kotcher, Elaine; Doremus, Richard R.

    During the spring of 1972 training workshops for 88 elementary and secondary teachers of the Great Neck Public Schools held to examine four hypotheses: 1) workshops in training teachers to observe classroom behavior would significantly increase these same teachers' positive classroom interactive behaviors consisting of teacher, pupil-pupil,…

  19. Education, Interaction, and Social Change.

    ERIC Educational Resources Information Center

    Hodgkinson, Harold L.

    This book examines the interaction of education and other elements in our culture. The social system of education is seen as similar to that of such other formal social institutions as business. Moreover, an understanding of the role and function of education can be achieved through an application of social science theory and research findings.…

  20. Literary Gaps Invite Creative Interaction.

    ERIC Educational Resources Information Center

    Watson, Jerry J.

    Literary gaps were identified by Wolfgang Iser in 1974 as "vacant pages" that invite the reader to reflect and enter into the text thereby motivating students to experience the text as reality. Arthur Applebee, in 1979, identified three categories to distinguish children's types of interaction with stories: (1) the complexity of literary…

  1. Inelastic final-state interaction

    SciTech Connect

    Suzuki, Mahiko; Suzuki, Mahiko

    2007-10-29

    The final-state interaction in multichannel decay processes is systematically studied with application to B decay in mind. Since the final-state interaction is intrinsically interwoven with the decay interaction in this case, no simple phase theorem like"Watson's theorem" holds for experimentally observed final states. We first examine in detail the two-channel problem as a toy-model to clarify the issues and to remedy common mistakes made in earlier literature. Realistic multichannel problems are too challenging for quantitative analysis. To cope with mathematical complexity, we introduce a method of approximation that is applicable to the case where one prominent inelastic channel dominates over all others. We illustrate this approximation method in the amplitude of the decay B to pi K fed by the intermediate states of a charmed meson pair. Even with our approximation we need more accurate information of strong interactions than we have now. Nonetheless we are able to obtain some insight in the issue and draw useful conclusions on general features on the strong phases.

  2. Seven Statements on Interactive Video.

    ERIC Educational Resources Information Center

    Gastkemper, F.

    This paper is concerned with the educational significance of interactive video. To clarify this, seven basic educational concepts are reviewed: (1) education and training are organized forms of learning; (2) goals and objectives can be grouped into the cognitive, affective, and psychomotor domains of learning; (3) education refers to learning…

  3. Gendered Language in Interactive Discourse

    ERIC Educational Resources Information Center

    Hussey, Karen A.; Katz, Albert N.; Leith, Scott A.

    2015-01-01

    Over two studies, we examined the nature of gendered language in interactive discourse. In the first study, we analyzed gendered language from a chat corpus to see whether tokens of gendered language proposed in the gender-as-culture hypothesis (Maltz and Borker in "Language and social identity." Cambridge University Press, Cambridge, pp…

  4. Microcomputer Applications in Interaction Analysis.

    ERIC Educational Resources Information Center

    Wadham, Rex A.

    The Timed Interval Categorical Observation Recorder (TICOR), a portable, battery powered microcomputer designed to automate the collection of sequential and simultaneous behavioral observations and their associated durations, was developed to overcome problems in gathering subtle interaction analysis data characterized by sequential flow of…

  5. Interactive Video Disc Orientation Documentation.

    ERIC Educational Resources Information Center

    Frost, William J.; And Others

    This report provides the documentation for a proposed interactive videodisk to be produced for use in orienting freshman students to the Harvey A. Andruss Library of Bloomsburg University (Pennsylvania). A rationale for the project and a plan of action are followed by a production time line and tentative program outline. An outline of the library…

  6. Early Mother-Child Interaction.

    ERIC Educational Resources Information Center

    d'Agostino, Micheline

    1986-01-01

    This journal issue presents an overview of mother-child interaction during the first year of the child's life. Contents of the first section, which concern the development of the mother-child relationship, focus on the concept of the maternal instinct, mother and child during intrauterine life, birth of the child, the postnatal period (including…

  7. Gendered Language in Interactive Discourse

    ERIC Educational Resources Information Center

    Hussey, Karen A.; Katz, Albert N.; Leith, Scott A.

    2015-01-01

    Over two studies, we examined the nature of gendered language in interactive discourse. In the first study, we analyzed gendered language from a chat corpus to see whether tokens of gendered language proposed in the gender-as-culture hypothesis (Maltz and Borker in "Language and social identity." Cambridge University Press, Cambridge, pp…

  8. Labeled Postings for Asynchronous Interaction

    ERIC Educational Resources Information Center

    ChanLin, Lih-Juan; Chen, Yong-Ting; Chan, Kung-Chi

    2009-01-01

    The Internet promotes computer-mediated communications, and so asynchronous learning network systems permit more flexibility in time, space, and interaction than synchronous mode of learning. The key point of asynchronous learning is the materials for web-aided teaching and the flow of knowledge. This research focuses on improving online…

  9. Interactive Multimedia: Practice and Promise.

    ERIC Educational Resources Information Center

    Latchem, Colin, Ed.; And Others

    This book describes developments in interactive multimedia (IMM) in the early 1990s. Its aim is to provide educators, students, trainers, librarians, managers, and practitioners with an overview, not only of the directions and uses of the technology, but also of the research foundations and educational and contextual issues that need to be…

  10. Child Characteristics by Model Interactions.

    ERIC Educational Resources Information Center

    Featherstone, Helen J.

    Data from the 1969-70 and 1970-71 Head Start Planned Variation (HSPV)Study were used to examine program-child interactions. An effort was made to determine whether different preschool programs have different cognitive effects on different types of children. Seven hypotheses for the analysis of the data were generated from the results of the HSPV…

  11. TROPIX plasma interactions group report

    NASA Technical Reports Server (NTRS)

    Herr, Joel L.; Chock, Ricaurte

    1993-01-01

    The purpose is to summarize the spacecraft charging analysis conducted by the plasma interactions group during the period from April 1993 to July 1993, on the proposed TROPIX spacecraft, and to make design recommendations which will limit the detrimental effects introduced by spacecraft charging. The recommendations were presented to the TROPIX study team at a Technical Review meeting held on 15 July 1993.

  12. Modeling Interactions in Small Groups

    ERIC Educational Resources Information Center

    Heise, David R.

    2013-01-01

    A new theory of interaction within small groups posits that group members initiate actions when tension mounts between the affective meanings of their situational identities and impressions produced by recent events. Actors choose partners and behaviors so as to reduce the tensions. A computer model based on this theory, incorporating reciprocal…

  13. Interaction of Nanoparticles with Biofilms

    EPA Science Inventory

    In this work we have studied the interaction and adsorption of engineered nanoparticles such as TiO2, ZnO, CeO2 , and carbon nanotubes with biofilms. Biofilm is an extracellular polymeric substance coating comprised of living material and it is an aggregation of bacteria, algae, ...

  14. A Computer Interactive Simulation Game

    ERIC Educational Resources Information Center

    Crawford, A. Berry; McKee, Mac

    1975-01-01

    Discussed is a simulation game designed to acquaint environmental planners and resource managers with the problems and interactions involved in an environmental system. A description of the structure, rules, and dynamics of the game is presented. Also included are recommendations and an example of the game. (MR)

  15. Interaction quenches of Fermi gases

    SciTech Connect

    Uhrig, Goetz S.

    2009-12-15

    It is shown that the jump in the momentum distribution of Fermi gases evolves smoothly for small and intermediate times once an interaction between the fermions is suddenly switched on. The jump does not vanish abruptly. The loci in momentum space where the jumps occur are those of the noninteracting Fermi sea. No relaxation of the Fermi surface geometry takes place.

  16. Deciding among interactive multimedia technologies.

    PubMed

    Locatis, C

    1995-01-01

    The history of multimedia technology is reviewed briefly as are some current health science applications. Multimedia hardware and software are discussed. Cost and benefits of current interactive multimedia technologies are assessed and key factors affecting their successful application are identified and described.

  17. Interactive graphics nonlinear constrained optimization

    NASA Technical Reports Server (NTRS)

    Saouma, V. E.; Sikiotis, E. S.

    1984-01-01

    An interactive computer graphics environment was used for nonlinear constrained optimization analysis. It is found that by combining the power of a digital computer with the subtlety of engineering judgment during program execution, final results can be substantially better than the ones achieved by the numerical algorithm by itself.

  18. AIP and its interacting partners.

    PubMed

    Trivellin, Giampaolo; Korbonits, Márta

    2011-08-01

    Germline mutations in the aryl hydrocarbon receptor-interacting protein gene (AIP) predispose to young-onset pituitary tumours, most often to GH- or prolactin-secreting adenomas, and most of these patients belong to familial isolated pituitary adenoma families. The molecular pathway initiated by the loss-of-function AIP mutations leading to pituitary tumour formation is unknown. AIP, a co-chaperone of heat-shock protein 90 and various nuclear receptors, belongs to the family of tetratricopeptide repeat (TPR)-containing proteins. It has three antiparallel α-helix motifs (TPR domains) that mediate the interaction of AIP with most of its partners. In this review, we summarise the known interactions of AIP described so far. The identification of AIP partners and the understanding of how AIP interacts with these proteins might help to explain the specific phenotype of the families with heterozygous AIP mutations, to gain deeper insight into the pathological process of pituitary tumour formation and to identify novel drug targets.

  19. Work Cognitions in Multicultural Interaction.

    ERIC Educational Resources Information Center

    Holt, John; Keats, Daphne M.

    1992-01-01

    Investigates the influence of ethnic cultural background and multicultural interaction for 120 males drawn from Aboriginal, Anglo-Saxon, Chinese, and Lebanese cultural communities in Australia. Responses to the Work Cognitions Questionnaire reveal differences in the structure of achievement goals and work values for the 4 groups of 30 subjects…

  20. Classroom Interaction and Language Output

    ERIC Educational Resources Information Center

    Wang, Qiaoying; Castro, Carolyn D.

    2010-01-01

    This study investigates the effects of classroom interactions between a) students and students and b) students and teachers on the learning of English passivization by L1 Chinese adult learners of English as a foreign language during the language input and output treatments. In phase 1, both groups were asked to read and underline the input…

  1. Interaction in the dark sector

    NASA Astrophysics Data System (ADS)

    del Campo, Sergio; Herrera, Ramón; Pavón, Diego

    2015-06-01

    It may well happen that the two main components of the dark sector of the Universe, dark matter and dark energy, do not evolve separately but interact nongravitationally with one another. However, given our current lack of knowledge of the microscopic nature of these two components, there is no clear theoretical path to determine their interaction. Yet, over the years, phenomenological interaction terms have been proposed on mathematical simplicity and heuristic arguments. In this paper, based on the likely evolution of the ratio between the energy densities of these dark components, we lay down reasonable criteria to obtain phenomenological, useful, expressions of the said term independent of any gravity theory. We illustrate this with different proposals which seem compatible with the known evolution of the Universe at the background level. Likewise, we show that two possible degeneracies with noninteracting models are only apparent as they can be readily broken at the background level. Further, we analyze some interaction terms that appear in the literature.

  2. Lateral interactions and enhanced adsorption

    NASA Astrophysics Data System (ADS)

    Rikvold, Per Arne; Deakin, Mark R.

    1991-06-01

    We extend earlier work on the effects of lateral adsorbate-adsorbate interactions in systems with two different adsorbate species to consider in detail enhanced adsorption phenomena. We give a detailed explanation of the enhancement mechanism for a lattice-gas model in thermodynamic equilibrium, and provide explicit quantitative criteria which must be satisfied by the effective lateral interactions in systems exhibiting strong, intermediate, or weak enhancement behavior. It is the examination and understanding of the topological details of the ground-state and phase diagrams of the model that allow the formulation of these criteria. The theoretically obtained criteria are supported by precise numerical calculations (transfer-matrix with strip width six) of adsorption isotherms for a three-state lattice-gas model with nearest-neighbor interactions on a triangular lattice. The applicability of this theoretical framework is illustrated by an analysis of experimental adsorption isotherms for the electrochemical adsorption of naphthalene on copper and n-decylamine on nickel, previously obtained by Bockris et al. As suggested by Damaskin et al. we attribute the potential dependence of the organic coverage to the influence of coadsorbed hydrogen. We find that nonlinear least-squares fits of numerical lattice-gas isotherms to the experimental data produce good agreement between the experimental and numerical adsorption isotherms, as well as effective lattice-gas interaction energies consistent with independent estimates from the literature.

  3. Interaction of Nanoparticles with Biofilms

    EPA Science Inventory

    In this work we have studied the interaction and adsorption of engineered nanoparticles such as TiO2, ZnO, CeO2 , and carbon nanotubes with biofilms. Biofilm is an extracellular polymeric substance coating comprised of living material and it is an aggregation of bacteria, algae, ...

  4. Interaction in Distance Nursing Education

    ERIC Educational Resources Information Center

    Boz Yuksekdag, Belgin

    2012-01-01

    The purpose of this study is to determine psychiatry nurses' attitudes toward the interactions in distance nursing education, and also scrunize their attitudes based on demographics and computer/Internet usage. The comparative relational scanning model is the method of this study. The research data were collected through "The Scale of Attitudes of…

  5. Effective interactions between fluid membranes

    NASA Astrophysics Data System (ADS)

    Lu, Bing-Sui; Podgornik, Rudolf

    2015-08-01

    A self-consistent theory is proposed for the general problem of interacting undulating fluid membranes subject to the constraint that they do not interpenetrate. We implement the steric constraint via an exact functional integral representation and, through the use of a saddle-point approximation, transform it into a novel effective steric potential. The steric potential is found to consist of two contributions: one generated by zero-mode fluctuations of the membranes and the other by thermal bending fluctuations. For membranes of cross-sectional area S , we find that the bending fluctuation part scales with the intermembrane separation d as d-2 for d ≪√{S } but crosses over to d-4 scaling for d ≫√{S } , whereas the zero-mode part of the steric potential always scales as d-2. For membranes interacting exclusively via the steric potential, we obtain closed-form expressions for the effective interaction potential and for the rms undulation amplitude σ , which becomes small at low temperatures T and/or large bending stiffnesses κ . Moreover, σ scales as d for d ≪√{S } but saturates at √{kBT S /κ } for d ≫√{S } . In addition, using variational Gaussian theory, we apply our self-consistent treatment to study intermembrane interactions subject to different types of potentials: (i) the Moreira-Netz potential for a pair of strongly charged membranes with an intervening solution of multivalent counterions, (ii) an attractive square well, (iii) the Morse potential, and (iv) a combination of hydration and van der Waals interactions.

  6. Star-Planet-Disk Interactions

    NASA Astrophysics Data System (ADS)

    Lai, Dong

    Observations of exoplanetary systems containing hot Jupiters have revealed a number of outstanding puzzles that beg for theoretical understanding. Magnetic interactions between young stars and proto-planetary disks and tidal interactions between stars and planets play an important role in shaping the observed properties of planets and planetary systems. We propose a multifaceted theoretical/computational program devoted to understanding these interactions. (1) We will study a novel “magnetic misalignment” effect in protostar-disk systems. Our recent work shows that magnetic star-disk interactions can produce secular changes in the stellar spin direction through magnetic torques, so that the stellar spin may not always be perpendicular to the disk. Our proposed research will consider more realistic models of star-disk interactions, including 3D numerical simulations. We will examine how spin- disk misalignment may explain the small (7 degree) spin-orbit misalignment in the Solar System and contribute to the recently observed spin-orbit misalignments in exoplanetary systems. (2) We will study dynamical tides (including thermal forcing) in hot Jupiters and explore how they may contribute to the observed planetary radius “anomaly”. We will also study dynamical tides in the host star raised by a hot Jupiter in an inclined orbit to understand how tidal dissipations may affect the spin-orbit misalignment angles and planetary orbital decay. This proposal is highly relevant to several goals of the Origins of Solar Systems program, including (a) characterization of other planetary systems, (b) interpretation of observations related to the formation and evolution of planetary systems, and (c) theoretical investigations related to the formation and evolution of planetary systems. The proposed research will contribute to the NASA vision statement and goal to “Advance scientific knowledge of the origin and history of the solar system ...”.

  7. Molecular interactions between desmosomal cadherins.

    PubMed Central

    Syed, Shabih-e-Hassnain; Trinnaman, Brian; Martin, Stephen; Major, Sarah; Hutchinson, Jon; Magee, Anthony I

    2002-01-01

    Desmocollins (Dscs) and desmogleins (Dsgs) are cell-adhesion molecules involved in the formation of desmosome cell-cell junctions and share structural similarities to classical cadherins such as E-cadherin. In order to identify and provide quantitative information on the types of protein-protein interactions displayed by the type 2 isoforms and investigate the role of Ca(2+) in this process, we have developed an Escherichia coli expression system to generate recombinant proteins containing the first two extracellular domains, namely Dsg2(1-2) and Dsc2(1-2). Analytical ultracentrifugation, chemical cross-linking, CD, fluorescence and BIAcore have been used to provide the first direct evidence of Ca(2+) binding to desmosomal cadherins. These studies suggest that Dsc2(1-2) not only exhibits homophilic interactions in solution, but can also form heterophilic interactions with Dsg2(1-2). The latter, on the other hand, shows much weaker homophilic association. Our results further demonstrate that heterophilic interactions are Ca(2+)-dependent, whereas the Ca(2+)-dependence of homophilic association is less clear. Our data indicate that the functional properties of Dsc2(1-2) are more similar to those of classical cadherins, consistent with the observation that Dsc shares a higher level of sequence homology with classical cadherins than does Dsg. In addition to corroborating the conclusions of previously reported transfection studies which suggest the formation of lateral heterodimers and homodimers, our results also provide direct quantitative information on the strength of these interactions which are essential for understanding the adhesion mechanism. PMID:11853539

  8. Spectra, composition, and interactions of nuclei with magnet interaction chambers

    NASA Technical Reports Server (NTRS)

    Parneil, T. A.; Derrickson, J. H.; Fountain, W. F.; Roberts, F. E.; Tabuki, T.; Watts, J. W.; Burnett, T. H.; Cherry, M. C.; Dake, S.; Fuki, M.

    1990-01-01

    Emulsion chambers will be flown in the Astromag Facility to measure the cosmic ray composition and spectra to 10 exp 15 eV total energy and to definitively study the characteristics of nucleus-nucleus interactions above 10 exp 12 eV/n. Two configurations of emulsion chambers will be flown in the SCIN/MAGIC experiment. One chamber has an emulsion target and a calorimeter similar to those recently flown on balloons for composition and spectra measurements. The other has an identical calorimeter and a low-density target section optimized for performing rigidity measurements on charged particles produced in interactions. The transverse momenta of charged and neutral mesons, direct hadronic pairs from resonance decays and interference effects, and possible charge clustering in high-density states of matter will be studied.

  9. Interactive Environment Design in Smart City

    NASA Astrophysics Data System (ADS)

    Deng, DeXiang; Chen, LanSha; Zhou, Xi

    2017-08-01

    The interactive environment design of smart city is not just an interactive progress or interactive mode design, rather than generate an environment such as the “organic” life entity as human beings through interactive design, forming a smart environment with perception, memory, thinking, and reaction.

  10. Adolescent Girls' Parasocial Interactions with Media Figures

    ERIC Educational Resources Information Center

    Theran, Sally A.; Newberg, Emily M.; Gleason, Tracy R.

    2010-01-01

    We examined aspects of adolescent girls' parasocial interactions in the context of typical development. Parasocial interactions are defined as symbolic, one-sided quasi-interactions between a viewer and a media figure. In total, 107 adolescent girls were examined; 94% reported engaging in parasocial interactions to some degree. Preoccupied…

  11. The Interaction Hypothesis: A Critical Evaluation.

    ERIC Educational Resources Information Center

    Ellis, Rod

    The oral interaction hypothesis, proposed by Long and investigated by Pica, in second language (L2) acquisition is critiqued. The interaction hypothesis advances two major claims about the role of interaction in L2 acquisition: (1) comprehensible input is necessary for L2 acquisition; and (2) modifications to the interactional structure of…

  12. Perturbation analyses of intermolecular interactions

    NASA Astrophysics Data System (ADS)

    Koyama, Yohei M.; Kobayashi, Tetsuya J.; Ueda, Hiroki R.

    2011-08-01

    Conformational fluctuations of a protein molecule are important to its function, and it is known that environmental molecules, such as water molecules, ions, and ligand molecules, significantly affect the function by changing the conformational fluctuations. However, it is difficult to systematically understand the role of environmental molecules because intermolecular interactions related to the conformational fluctuations are complicated. To identify important intermolecular interactions with regard to the conformational fluctuations, we develop herein (i) distance-independent and (ii) distance-dependent perturbation analyses of the intermolecular interactions. We show that these perturbation analyses can be realized by performing (i) a principal component analysis using conditional expectations of truncated and shifted intermolecular potential energy terms and (ii) a functional principal component analysis using products of intermolecular forces and conditional cumulative densities. We refer to these analyses as intermolecular perturbation analysis (IPA) and distance-dependent intermolecular perturbation analysis (DIPA), respectively. For comparison of the IPA and the DIPA, we apply them to the alanine dipeptide isomerization in explicit water. Although the first IPA principal components discriminate two states (the α state and PPII (polyproline II) + β states) for larger cutoff length, the separation between the PPII state and the β state is unclear in the second IPA principal components. On the other hand, in the large cutoff value, DIPA eigenvalues converge faster than that for IPA and the top two DIPA principal components clearly identify the three states. By using the DIPA biplot, the contributions of the dipeptide-water interactions to each state are analyzed systematically. Since the DIPA improves the state identification and the convergence rate with retaining distance information, we conclude that the DIPA is a more practical method compared with the

  13. IRAS study of interacting galaxies

    NASA Astrophysics Data System (ADS)

    Allam, S.

    1998-04-01

    Interacting galaxies are ideal laboratories for studying the influence of gravitational forces on galaxies. From theoretical and observational studies, we know how sensitive galaxies are to tidal interaction, from the formation of tidal tails, bridges, bursts of star formation up to a complete merging of the galaxies. The Far Infrared (FIR) properties of interacting galaxies give information on the dynamical and physical properties of these systems. Several earlier studies using the IRAS point source catalogue (IPSC) and IRAS Faint Source Survey (FSS), showed that the FIR emission from interacting/merging galaxies is enhanced with respect to isolated non-interacting galaxies; moreover, that high density environments have more influence in producing enhanced FIR emission over isolated interacting systems. In general the ratio of FIR to optical luminosity in interacting systems was found to be enhanced. It is regarded as an increased star formation (SF) rate in these systems. Later on, due to the rather high IPSC detection threshold, and its low resolution, several contradictory results have been reported. In this thesis the FIR emission from interacting galaxies is studied by using the high resolution IRAS software introduced by Bontekoe et al. (1994). This soft ware package uses a Maximum Entropy method (hereafter MaxEnt). The MaxEnt formulation is rooted in Bayesian probability theory. The raw IRAS data contains the Point Spread Function (PSF) of both the telescope mirror (60 cm --> 1 arcmin at 60 μm) and the PSF of the detectors (≃ 5 arcmin). Since there is much redundancy in the data, the MaxEnt routine can be used to remove the 5 arcmin PSF from the detectors. For many interacting galaxies this is enough to resolve them. The size of the images was chosen such that the objects could be studied including their surroundings. The absolute position calibration and flux estimates for the MaxEnt images are described in Allam et al. (1996). Because of the high

  14. Peer interaction: help or distraction?

    NASA Astrophysics Data System (ADS)

    Ruzhitskaya, Lanika; Speck, A.; Dr.

    2011-01-01

    We present our results on the difference in learning effectiveness of a particular concept in astronomy when students work as individuals as compared to working in pairs. We conducted a study based on the stellar parallax concept using two versions of a computer-based tutorial: guided and unguided. In this study students were randomly assigned to work in peer groups and individually. Students’ interactions with the two versions of the tutorial and their peer interactions were recorded using MORAE software for quantitative and qualitative analysis. In addition, we used pretest and two posttest questionnaires to find conceptual gain. Here we present our preliminary results on the emergence of particular patterns in students learning behavior when they work independently and with peers, and how guided or unguided exercises affect these patterns.

  15. Image reproduction with interactive graphics

    NASA Technical Reports Server (NTRS)

    Buckner, J. D.; Council, H. W.; Edwards, T. R.

    1974-01-01

    Software application or development in optical image digital data processing requires a fast, good quality, yet inexpensive hard copy of processed images. To achieve this, a Cambo camera with an f 2.8/150-mm Xenotar lens in a Copal shutter having a Graflok back for 4 x 5 Polaroid type 57 pack-film has been interfaced to an existing Adage, AGT-30/Electro-Mechanical Research, EMR 6050 graphic computer system. Time-lapse photography in conjunction with a log to linear voltage transformation has resulted in an interactive system capable of producing a hard copy in 54 sec. The interactive aspect of the system lies in a Tektronix 4002 graphic computer terminal and its associated hard copy unit.

  16. Interactive Learning During Solar Maximum

    NASA Technical Reports Server (NTRS)

    Ashour-Abdalla, Maha; Curtis, Steven (Technical Monitor)

    2001-01-01

    The goal of this project is to develop and distribute e-educational material for space science during times of solar activity that emphasizes underlying basic science principles of solar disturbances and their effects on Earth. This includes materials such as simulations, animations, group projects and other on-line materials to be used by students either in high school or at the introductory college level. The on-line delivery tool originally intended to be used is known as Interactive Multimedia Education at a Distance (IMED), which is a web-based software system used at UCLA for interactive distance learning. IMED is a password controlled system that allows students to access text, images, bulletin boards, chat rooms, animation, simulations and individual student web sites to study science and to collaborate on group projects.

  17. Pellet interaction with runaway electrons

    SciTech Connect

    James, A. N.; Hollmann, E. M.; Yu, J.H.; Austin, M. E.; Commaux, Nicolas JC; Evans, T.E.; Humphrey, D. A.; Jernigan, T. C.; Parks, P. B.; Putvinski, S.; Strait, E. J.; Tynan, G. R.; Wesley, J. C.

    2011-01-01

    We describe results from recent experiments studying interaction of solid polystyrene pellets with a runaway electron current channel generated after cryogenic argon pellet rapid shutdown of DIII-D. Fast camera imaging shows the pellet trajectory and continuum emission from the subsequent explosion, with geometric calibration providing detailed explosion analysis and runaway energy. Electron cyclotron emission also occurs, associated with knock-on electrons broken free from the pellet by RE which then accelerate and runaway, and also with a short lived hot plasma blown off the pellet surface. In addition, we compare heating and explosion times from observations and a model of pellet heating and breakdown by runaway interaction. (C) 2011 Elsevier B.V. All rights reserved

  18. OVERFLOW-Interaction with Industry

    NASA Technical Reports Server (NTRS)

    Buning, Pieter G.; George, Michael W. (Technical Monitor)

    1996-01-01

    A Navier-Stokes flow solver, OVERFLOW, has been developed by researchers at NASA Ames Research Center to use overset (Chimera) grids to simulate the flow about complex aerodynamic shapes. Primary customers of the OVERFLOW flow solver and related software include McDonnell Douglas and Boeing, as well as the NASA Focused Programs for Advanced Subsonic Technology (AST) and High Speed Research (HSR). Code development has focused on customer issues, including improving code performance, ability to run on workstation clusters and the NAS SP2, and direct interaction with industry on accuracy assessment and validation. Significant interaction with NAS has produced a capability tailored to the Ames computing environment, and code contributions have come from a wide range of sources, both within and outside Ames.

  19. The Interaction-Activity Connection

    NASA Technical Reports Server (NTRS)

    Borne, Kirk D.

    1996-01-01

    A review is presented of the numerous studies that have been undertaken to investigate the likely interaction-activity connection among galaxies. Both observational evidence and theoretical supporting models are reviewed. Some specific examples of "interactive" galaxies from the author's own research are presented: (a) the collision-induced AGN (Active Galactic Nuclei) activity in the radio jet source 3C278; and (b) the collision-induced starburst activity in the spectacular "Cartwheel" ring galaxy. Some comments are offered concerning some of the more promising theoretical investigations that are now taking place. A few words of warning are also offered about the possible misinterpretation of putative collision-induced morphologies among some galaxy samples.

  20. Image reproduction with interactive graphics

    NASA Technical Reports Server (NTRS)

    Buckner, J. D.; Council, H. W.; Edwards, T. R.

    1974-01-01

    Software application or development in optical image digital data processing requires a fast, good quality, yet inexpensive hard copy of processed images. To achieve this, a Cambo camera with an f 2.8/150-mm Xenotar lens in a Copal shutter having a Graflok back for 4 x 5 Polaroid type 57 pack-film has been interfaced to an existing Adage, AGT-30/Electro-Mechanical Research, EMR 6050 graphic computer system. Time-lapse photography in conjunction with a log to linear voltage transformation has resulted in an interactive system capable of producing a hard copy in 54 sec. The interactive aspect of the system lies in a Tektronix 4002 graphic computer terminal and its associated hard copy unit.