Sample records for light detection system

  1. [A review of mixed gas detection system based on infrared spectroscopic technique].

    PubMed

    Dang, Jing-Min; Fu, Li; Yan, Zi-Hui; Zheng, Chuan-Tao; Chang, Yu-Chun; Chen, Chen; Wang, Yi-Din

    2014-10-01

    In order to provide the experiences and references to the researchers who are working on infrared (IR) mixed gas detection field. The proposed manuscript reviews two sections of the aforementioned field, including optical multiplexing structure and detection method. At present, the coherent light sources whose representative are quantum cascade laser (QCL) and inter-band cascade laser(ICL) become the mainstream light source in IR mixed gas detection, which replace the traditional non-coherent light source, such as IR radiation source and IR light emitting diode. In addition, the photon detector which has a super high detectivity and very short response time is gradually beyond thermal infrared detector, dominant in the field of infrared detector. The optical multiplexing structure is the key factor of IR mixed gas detection system, which consists of single light source multi-plexing detection structure and multi light source multiplexing detection structure. Particularly, single light source multiplexing detection structure is advantages of small volume and high integration, which make it a plausible candidate for the portable mixed gas detection system; Meanwhile, multi light source multiplexing detection structure is embodiment of time division multiplex, frequency division multiplexing and wavelength division multiplexing, and become the leading structure of the mixed gas detection system because of its wider spectral range, higher spectral resolution, etc. The detection method applied to IR mixed gas detection includes non-dispersive infrared (NDIR) spectroscopy, wavelength and frequency-modulation spectroscopy, cavity-enhanced spectroscopy and photoacoustic spectroscopy, etc. The IR mixed gas detection system designed by researchers after recognizing the whole sections of the proposed system, which play a significant role in industrial and agricultural production, environmental monitoring, and life science, etc.

  2. Pedestrian Detection Based on Adaptive Selection of Visible Light or Far-Infrared Light Camera Image by Fuzzy Inference System and Convolutional Neural Network-Based Verification.

    PubMed

    Kang, Jin Kyu; Hong, Hyung Gil; Park, Kang Ryoung

    2017-07-08

    A number of studies have been conducted to enhance the pedestrian detection accuracy of intelligent surveillance systems. However, detecting pedestrians under outdoor conditions is a challenging problem due to the varying lighting, shadows, and occlusions. In recent times, a growing number of studies have been performed on visible light camera-based pedestrian detection systems using a convolutional neural network (CNN) in order to make the pedestrian detection process more resilient to such conditions. However, visible light cameras still cannot detect pedestrians during nighttime, and are easily affected by shadows and lighting. There are many studies on CNN-based pedestrian detection through the use of far-infrared (FIR) light cameras (i.e., thermal cameras) to address such difficulties. However, when the solar radiation increases and the background temperature reaches the same level as the body temperature, it remains difficult for the FIR light camera to detect pedestrians due to the insignificant difference between the pedestrian and non-pedestrian features within the images. Researchers have been trying to solve this issue by inputting both the visible light and the FIR camera images into the CNN as the input. This, however, takes a longer time to process, and makes the system structure more complex as the CNN needs to process both camera images. This research adaptively selects a more appropriate candidate between two pedestrian images from visible light and FIR cameras based on a fuzzy inference system (FIS), and the selected candidate is verified with a CNN. Three types of databases were tested, taking into account various environmental factors using visible light and FIR cameras. The results showed that the proposed method performs better than the previously reported methods.

  3. Portable light detection system for the blind

    NASA Technical Reports Server (NTRS)

    Wilber, R. L.; Carpenter, B. L.

    1973-01-01

    System can be used to detect "ready" light on automatic cooking device, to tell if lights are on for visitors, or to tell whether it is daylight or dark outside. Device is actuated like flashlight. Light impinging on photo cell activates transistor which energizes buzzer to indicate presence of light.

  4. Systems and Methods for Automated Water Detection Using Visible Sensors

    NASA Technical Reports Server (NTRS)

    Rankin, Arturo L. (Inventor); Matthies, Larry H. (Inventor); Bellutta, Paolo (Inventor)

    2016-01-01

    Systems and methods are disclosed that include automated machine vision that can utilize images of scenes captured by a 3D imaging system configured to image light within the visible light spectrum to detect water. One embodiment includes autonomously detecting water bodies within a scene including capturing at least one 3D image of a scene using a sensor system configured to detect visible light and to measure distance from points within the scene to the sensor system, and detecting water within the scene using a processor configured to detect regions within each of the at least one 3D images that possess at least one characteristic indicative of the presence of water.

  5. Particle measurement systems and methods

    DOEpatents

    Steele, Paul T [Livermore, CA

    2011-10-04

    A system according to one embodiment includes a light source for generating light fringes; a sampling mechanism for directing a particle through the light fringes; and at least one light detector for detecting light scattered by the particle as the particle passes through the light fringes. A method according to one embodiment includes generating light fringes using a light source; directing a particle through the light fringes; and detecting light scattered by the particle as the particle passes through the light fringes using at least one light detector.

  6. Multispectral imaging system for contaminant detection

    NASA Technical Reports Server (NTRS)

    Poole, Gavin H. (Inventor)

    2003-01-01

    An automated inspection system for detecting digestive contaminants on food items as they are being processed for consumption includes a conveyor for transporting the food items, a light sealed enclosure which surrounds a portion of the conveyor, with a light source and a multispectral or hyperspectral digital imaging camera disposed within the enclosure. Operation of the conveyor, light source and camera are controlled by a central computer unit. Light reflected by the food items within the enclosure is detected in predetermined wavelength bands, and detected intensity values are analyzed to detect the presence of digestive contamination.

  7. Stray light suppression of optical and mechanical system for telescope detection

    NASA Astrophysics Data System (ADS)

    Wang, Lei; Ma, Wenli

    2013-09-01

    During telescope detection, there is atmosphere overflow and other stray light affecting the system which leads to background disturbance. Thus reduce the detection capability of the system. So it is very necessary to design mechanical structure to suppress the stray light for the telescope detection system. It can both improve the signal-to-noise and contrast of the object. This paper designs the optical and mechanical structure of the 400mm telescope. And then the main baffle, baffle vane, field stop and coating technology are used to eliminate the effect of stray light on the optical and mechanical system. Finally, software is used to analyze and simulate stray light on the whole optical and mechanical system. Using PST as the evaluating standard, separate and integrated analysis of the suppressing effect of main baffle, baffle vane and field aperture is completed. And also get the results of PST before and after eliminating the stray light. Meanwhile, the results of stray light analysis can be used to guide the design of the optical and mechanical structure. The analysis results demonstrate that reasonable optical and mechanical structure and stray light suppression measure can highly reduce the PST and also improve the detection capability of the telescope system, and the designed outside baffle, inside baffle, vanes and coating technique etc. can decrease the PST approximately 1 to 3 level.

  8. Upconverting nanoparticles for optimizing scintillator based detection systems

    DOEpatents

    Kross, Brian; McKisson, John E; McKisson, John; Weisenberger, Andrew; Xi, Wenze; Zom, Carl

    2013-09-17

    An upconverting device for a scintillation detection system is provided. The detection system comprises a scintillator material, a sensor, a light transmission path between the scintillator material and the sensor, and a plurality of upconverting nanoparticles particles positioned in the light transmission path.

  9. [System design of open-path natural gas leakage detection based on Fresnel lens].

    PubMed

    Xia, Hui; Liu, Wen-Qing; Zhang, Yu-Jun; Kan, Rui-Feng; Cui, Yi-Ben; Wang, Min; He, Ying; Cui, Xiao-Juan; Ruan, Jun; Geng, Hui

    2009-03-01

    Based on the technology of tunable diode laser absorption spectroscopy (TDLAS) in conjunction with second harmonic wave detection, a long open-path TDLAS system using a 1.65 microm InGaAsP distributed feedback laser was developed, which is used for detecting pipeline leakage. In this system, a high cost performance Fresnel lens is used as the receiving optical system, which receives the laser-beam reflected by a solid corner cube reflector, and focuses the receiving laser-beam to the InGaAs detector. At the same time, the influences of the concentration to the fluctuation of light intensity were taken into account in the process of measurement, and were eliminated by the method of normalized light intensity. As a result, the measurement error caused by the fluctuation of light intensity was made less than 1%. The experiment of natural gas leakage detection was simulated, and the detection sensitivity is 0.1 x 10(-6) (ratio by volume) with a total path of 320 m. According to the receiving light efficiency of the optical system and the detectable minimum light intensity of the detector, the detectable maximal optical path of the system was counted to be 2 000 m. The results of experiment show that it is a feasible design to use the Fresnel lens as the receiving optical system and can satisfy the demand of the leakage detection of natural gas.

  10. Influence of incident angle on the decoding in laser polarization encoding guidance

    NASA Astrophysics Data System (ADS)

    Zhou, Muchun; Chen, Yanru; Zhao, Qi; Xin, Yu; Wen, Hongyuan

    2009-07-01

    Dynamic detection of polarization states is very important for laser polarization coding guidance systems. In this paper, a set of dynamic polarization decoding and detection system used in laser polarization coding guidance was designed. Detection process of the normal incident polarized light is analyzed with Jones Matrix; the system can effectively detect changes in polarization. Influence of non-normal incident light on performance of polarization decoding and detection system is studied; analysis showed that changes in incident angle will have a negative impact on measure results, the non-normal incident influence is mainly caused by second-order birefringence and polarization sensitivity effect generated in the phase delay and beam splitter prism. Combined with Fresnel formula, decoding errors of linearly polarized light, elliptically polarized light and circularly polarized light with different incident angles into the detector are calculated respectively, the results show that the decoding errors increase with increase of incident angle. Decoding errors have relations with geometry parameters, material refractive index of wave plate, polarization beam splitting prism. Decoding error can be reduced by using thin low-order wave-plate. Simulation of detection of polarized light with different incident angle confirmed the corresponding conclusions.

  11. 46 CFR 111.05-21 - Ground detection.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL... be ground detection for each: (a) Electric propulsion system; (b) Ship's service power system; (c) Lighting system; and (d) Power or lighting distribution system that is isolated from the ship's service...

  12. 46 CFR 111.05-21 - Ground detection.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL... be ground detection for each: (a) Electric propulsion system; (b) Ship's service power system; (c) Lighting system; and (d) Power or lighting distribution system that is isolated from the ship's service...

  13. 46 CFR 111.05-21 - Ground detection.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL... be ground detection for each: (a) Electric propulsion system; (b) Ship's service power system; (c) Lighting system; and (d) Power or lighting distribution system that is isolated from the ship's service...

  14. Analysis of Tyman green detection system based on polarization interference

    NASA Astrophysics Data System (ADS)

    Huang, Yaolin; Wang, Min; Shao, Xiaoping; Kou, Yuanfeng

    2018-02-01

    The optical surface deviation of the lens can directly affect the quality of the optical system.In order to effectively and accurately detect the surface shape, an optical surface on-line detection system based on polarization interference technology is designed and developed. The system is based on Tyman-Green interference optical path, join the polarization interference measuring technology. Based on the theoretical derivation of the optical path and the ZEMAX software simulation, the experimental optical path is constructed. The parallel light is used to detect the concave lens. The parallel light is used as the light source, the size of the polarization splitting prism, detection radius of curvature, the relations between and among the size of the lens aperture, a detection range is given.

  15. Underwater detectibility of a lighting system on a helicopter escape exit.

    PubMed

    O'Neill, Brendan D; Kozey, John W; Brooks, Chris J

    2004-06-01

    When a helicopter ditches into water, it immediately inverts due to the weight of the engines and then fills with water. Locating the emergency exit for escape under such conditions is a difficult task. A new lighting system for an escape exit has been developed that illuminates on contact with water. The detectibility of the lighting was investigated under varying conditions of ambient illumination, water turbidity, and viewing distance. A total of 288 underwater detection trials were carried out by 9 subjects with an illuminated hatch placed at 2 distances (1.5 m and 3.1 m), under 2 ambient illuminations (bright: > 3000 lux and dark: < 0.1 lux), and in 2 conditions of water turbidity. The water temperature was 12 degrees C for all conditions. At 1.5 m, the lighting system was detectable in less than 1.5 s by all subjects in both clear and turbid water and under both bright and dark conditions. At 3.1 m, the lights were detectable in both clear and turbid water under the dark condition and in clear water under the bright condition. However, the lighting was not reliably detected in turbid water under bright condition. The system met original design requirements in terms of detectibility at 1.5 m. The detection time was always under 1.5 s. It could also be detected at 3.1 m in clear and turbid water, under dark conditions. However, the detectibility at 3.1 m in turbid water, under bright condition was less reliable.

  16. Room-temperature quantum noise limited spectrometry and methods of the same

    DOEpatents

    Stevens, Charles G.; Tringe, Joseph W.; Cunningham, Christopher Thomas

    2014-08-26

    In one embodiment, a heterodyne detection system for detecting light includes a first input aperture adapted for receiving first light from a scene input, a second input aperture adapted for receiving second light from a local oscillator input, a broadband local oscillator adapted for providing the second light to the second input aperture, a dispersive element adapted for dispersing the first light and the second light, and a final condensing lens coupled to an infrared detector. The final condensing lens is adapted for concentrating incident light from a primary condensing lens onto the infrared detector, and the infrared detector is a square-law detector capable of sensing the frequency difference between the first light and the second light. More systems and methods for detecting light are described according to other embodiments.

  17. Room-temperature quantum noise limited spectrometry and methods of the same

    DOEpatents

    Stevens, Charles G; Tringe, Joseph W

    2014-12-02

    In one embodiment, a heterodyne detection system for detecting light includes a first input aperture adapted for receiving a first light from a scene input, a second input aperture adapted for receiving a second light from a local oscillator input, a broadband local oscillator adapted for providing the second light to the second input aperture, a dispersive element adapted for dispersing the first light and the second light, and a final condensing lens coupled to an infrared detector. The final condensing lens is adapted for concentrating incident light from a primary condensing lens onto the detector, and the detector is a square-law detector capable of sensing the frequency difference between the first light and the second light. More systems and methods for detecting light are disclosed according to more embodiments.

  18. Room-temperature quantum noise limited spectrometry and methods of the same

    DOEpatents

    Stevens, Charles G.; Tringe, Joseph W.; Cunningham, Christopher T.

    2016-08-02

    In one embodiment, a heterodyne detection system for detecting light includes a first input aperture configured to receive first light from a scene input, a second input aperture configured to receive second light from a local oscillator input, a broadband local oscillator configured to provide the second light to the second input aperture, a dispersive element configured to disperse the first light and the second light, and a final condensing lens coupled to an infrared detector. The final condensing lens is configured to concentrate incident light from a primary condensing lens onto the infrared detector, and the infrared detector is a square-law detector capable of sensing the frequency difference between the first light and the second light. More systems and methods for detecting light are described according to other embodiments.

  19. An inter-lighting interference cancellation scheme for MISO-VLC systems

    NASA Astrophysics Data System (ADS)

    Kim, Kyuntak; Lee, Kyujin; Lee, Kyesan

    2017-08-01

    In this paper, we propose an inter-lighting interference cancellation (ILIC) scheme to reduce the interference between adjacent light-emitting diodes (LEDs) and enhance the transmission capacity of multiple-input-single-output (MISO)-visible light communication (VLC) systems. In indoor environments, multiple LEDs have normally been used as lighting sources, allowing the design of MISO-VLC systems. To enhance the transmission capacity, different data should be simultaneously transmitted from each LED; however, that can lead to interference between adjacent LEDs. In that case, relatively low-received power signals are subjected to large interference because wireless optical systems generally use intensity modulation and direct detection. Thus, only the signal with the highest received power can be detected, while the other received signals cannot be detected. To solve this problem, we propose the ILIC scheme for MISO-VLC systems. The proposed scheme preferentially detects the highest received power signal, and this signal is referred as interference signal by an interference component generator. Then, relatively low-received power signal can be detected by cancelling the interference signal from the total received signals. Therefore, the performance of the proposed scheme can improve the total average bit error rate and throughput of a MISO-VLC system.

  20. Miniaturized high throughput detection system for capillary array electrophoresis on chip with integrated light emitting diode array as addressed ring-shaped light source.

    PubMed

    Ren, Kangning; Liang, Qionglin; Mu, Xuan; Luo, Guoan; Wang, Yiming

    2009-03-07

    A novel miniaturized, portable fluorescence detection system for capillary array electrophoresis (CAE) on a microfluidic chip was developed, consisting of a scanning light-emitting diode (LED) light source and a single point photoelectric sensor. Without charge coupled detector (CCD), lens, fibers and moving parts, the system was extremely simplified. Pulsed driving of the LED significantly increased the sensitivity, and greatly reduced the power consumption and photobleaching effect. The highly integrated system was robust and easy to use. All the advantages realized the concept of a portable micro-total analysis system (micro-TAS), which could work on a single universal serial bus (USB) port. Compared with traditional CAE detecting systems, the current system could scan the radial capillary array with high scanning rate. An 8-channel CAE of fluorescein isothiocyanate (FITC) labeled arginine (Arg) on chip was demonstrated with this system, resulting in a limit of detection (LOD) of 640 amol.

  1. Oil and gas exploration system and method for detecting trace amounts of hydrocarbon gases in the atmosphere

    DOEpatents

    Wamsley, Paula R.; Weimer, Carl S.; Nelson, Loren D.; O'Brien, Martin J.

    2003-01-01

    An oil and gas exploration system and method for land and airborne operations, the system and method used for locating subsurface hydrocarbon deposits based upon a remote detection of trace amounts of gases in the atmosphere. The detection of one or more target gases in the atmosphere is used to indicate a possible subsurface oil and gas deposit. By mapping a plurality of gas targets over a selected survey area, the survey area can be analyzed for measurable concentration anomalies. The anomalies are interpreted along with other exploration data to evaluate the value of an underground deposit. The system includes a differential absorption lidar (DIAL) system with a spectroscopic grade laser light and a light detector. The laser light is continuously tunable in a mid-infrared range, 2 to 5 micrometers, for choosing appropriate wavelengths to measure different gases and avoid absorption bands of interference gases. The laser light has sufficient optical energy to measure atmospheric concentrations of a gas over a path as long as a mile and greater. The detection of the gas is based on optical absorption measurements at specific wavelengths in the open atmosphere. Light that is detected using the light detector contains an absorption signature acquired as the light travels through the atmosphere from the laser source and back to the light detector. The absorption signature of each gas is processed and then analyzed to determine if a potential anomaly exists.

  2. System for In-Situ Detection of Plant Exposure to Trichloroethylene (TCE)

    NASA Technical Reports Server (NTRS)

    Newman, Lee A. (Inventor); Lewis, Mark D. (Inventor); Anderson, Daniel J. (Inventor); Keith, Amy G. (Inventor)

    2013-01-01

    A system detects a plant's exposure to trichloroethylene (TCE) through plant leaf imaging. White light impinging upon a plant's leaf interacts therewith to produce interacted light. A detector is positioned to detect at least one spectral band of the interacted light. A processor coupled to the detector performs comparisons between photonic energy of the interacted light at the one or more spectral bands thereof and reference data defining spectral responses indicative of leaf exposure to TCE. An output device coupled to the processor provides indications of the comparisons.

  3. Space and time resolved representation of a vacuum arc light emission

    NASA Astrophysics Data System (ADS)

    Georgescu, N.; Sandolache, G.; Zoita, V.

    1999-04-01

    An optoelectronic multichannel detection system for the study of the visible light emission of a vacuum circuit breaker arc is described. The system consists of two multiple slit collimator assemblies coupled directly to the arc discharge chamber and an electronic detection part. The light emitted by the arc is collected by the two collimator assemblies and is transmitted through optical fibres to the electronic detection part. By using a new, simple computational method two-dimensional plots of the vacuum arc light emission at different times are obtained.

  4. Method of analyzing multiple sample simultaneously by detecting absorption and systems for use in such a method

    DOEpatents

    Yeung, Edward S.; Gong, Xiaoyi

    2004-09-07

    The present invention provides a method of analyzing multiple samples simultaneously by absorption detection. The method comprises: (i) providing a planar array of multiple containers, each of which contains a sample comprising at least one absorbing species, (ii) irradiating the planar array of multiple containers with a light source and (iii) detecting absorption of light with a detetion means that is in line with the light source at a distance of at leaat about 10 times a cross-sectional distance of a container in the planar array of multiple containers. The absorption of light by a sample indicates the presence of an absorbing species in it. The method can further comprise: (iv) measuring the amount of absorption of light detected in (iii) indicating the amount of the absorbing species in the sample. Also provided by the present invention is a system for use in the abov metho.The system comprises; (i) a light source comrnpising or consisting essentially of at leaat one wavelength of light, the absorption of which is to be detected, (ii) a planar array of multiple containers, and (iii) a detection means that is in line with the light source and is positioned in line with and parallel to the planar array of multiple contiainers at a distance of at least about 10 times a cross-sectional distance of a container.

  5. System and Method for Determining Fluence of a Substance

    NASA Technical Reports Server (NTRS)

    Banks, Bruce A. (Inventor)

    2016-01-01

    A system and method for measuring a fluence of gas are disclosed. The system has a first light detector capable of outputting an electrical signal based on an amount of light received. A barrier is positionable adjacent the first light detector and is susceptible to a change in dimension from the fluence of the gas. The barrier permits a portion of light from being received by the first light detector. The change in the dimension of the barrier changes the electrical signal output from the first light detector. A second light detector is positionable to receive light representative of the first light detector without the barrier. The system and method have broad application to detect fluence of gas that may cause erosion chemical reaction causing erosive deterioration. One application is in low orbit Earth for detecting the fluence of atomic oxygen.

  6. Wave study of compound eyes for efficient infrared detection

    NASA Astrophysics Data System (ADS)

    Kilinc, Takiyettin Oytun; Hayran, Zeki; Kocer, Hasan; Kurt, Hamza

    2017-08-01

    Improving sensitivity in the infrared spectrum is a challenging task. Detecting infrared light over a wide bandwidth and at low power consumption is very important. Novel solutions can be acquired by mimicking biological eyes such as compound eye with many individual lenses inspired from the nature. The nature provides many ingenious approaches of sensing and detecting the surrounding environment. Even though compound eye consists of small optical units, it can detect wide-angle electromagnetic waves and it has high transmission and low reflection loss. Insects have eyes that are superior compared to human eyes (single-aperture eyes) in terms of compactness, robustness, wider field of view, higher sensitivity of light intensity and being cheap vision systems. All these desired properties are accompanied by an important drawback: lower spatial resolution. The first step to investigate the feasibility of bio-inspired optics in photodetectors is to perform light interaction with the optical system that gather light and detect it. The most common method used in natural vision systems is the ray analysis. Light wave characteristics are not taken into consideration in such analyses, such as the amount of energy at the focal point or photoreceptor site, the losses caused by reflection at the interfaces and absorption cannot be investigated. In this study, we present a bio-inspired optical detection system investigated by wave analysis. We numerically model the wave analysis based on Maxwell equations from the viewpoint of efficient light detection and revealing the light propagation after intercepting the first interface of the eye towards the photoreceptor site.

  7. Optical multi-species gas monitoring sensor and system

    NASA Technical Reports Server (NTRS)

    Korman, Valentin (Inventor); Polzin, Kurt A. (Inventor)

    2012-01-01

    The system includes at least one light source generating light energy having a corresponding wavelength. The system's sensor is based on an optical interferometer that receives light energy from each light source. The interferometer includes a free-space optical path disposed in an environment of interest. The system's sensor includes an optical device disposed in the optical path that causes light energy of a first selected wavelength to continue traversing the optical path whereas light energy of at least one second selected wavelength is directed away from the optical path. The interferometer generates an interference between the light energy of the first selected wavelength so-traversing the optical path with the light energy at the corresponding wavelength incident on the optical interferometer. A first optical detector detects the interference. At least one second detector detects the light energy at the at least one second selected wavelength directed away from the optical path.

  8. Radiation detection system

    DOEpatents

    Nelson, Melvin A.; Davies, Terence J.; Morton, III, John R.

    1976-01-01

    A radiation detection system which utilizes the generation of Cerenkov light in and the transmission of that light longitudinally through fiber optic wave guides in order to transmit intelligence relating to the radiation to a remote location. The wave guides are aligned with respect to charged particle radiation so that the Cerenkov light, which is generated at an angle to the radiation, is accepted by the fiber for transmission therethrough. The Cerenkov radiation is detected, recorded, and analyzed at the other end of the fiber.

  9. A design of LED adaptive dimming lighting system based on incremental PID controller

    NASA Astrophysics Data System (ADS)

    He, Xiangyan; Xiao, Zexin; He, Shaojia

    2010-11-01

    As a new generation energy-saving lighting source, LED is applied widely in various technology and industry fields. The requirement of its adaptive lighting technology is more and more rigorous, especially in the automatic on-line detecting system. In this paper, a closed loop feedback LED adaptive dimming lighting system based on incremental PID controller is designed, which consists of MEGA16 chip as a Micro-controller Unit (MCU), the ambient light sensor BH1750 chip with Inter-Integrated Circuit (I2C), and constant-current driving circuit. A given value of light intensity required for the on-line detecting environment need to be saved to the register of MCU. The optical intensity, detected by BH1750 chip in real time, is converted to digital signal by AD converter of the BH1750 chip, and then transmitted to MEGA16 chip through I2C serial bus. Since the variation law of light intensity in the on-line detecting environment is usually not easy to be established, incremental Proportional-Integral-Differential (PID) algorithm is applied in this system. Control variable obtained by the incremental PID determines duty cycle of Pulse-Width Modulation (PWM). Consequently, LED's forward current is adjusted by PWM, and the luminous intensity of the detection environment is stabilized by self-adaptation. The coefficients of incremental PID are obtained respectively after experiments. Compared with the traditional LED dimming system, it has advantages of anti-interference, simple construction, fast response, and high stability by the use of incremental PID algorithm and BH1750 chip with I2C serial bus. Therefore, it is suitable for the adaptive on-line detecting applications.

  10. Localized surface plasmon resonance mercury detection system and methods

    DOEpatents

    James, Jay; Lucas, Donald; Crosby, Jeffrey Scott; Koshland, Catherine P.

    2016-03-22

    A mercury detection system that includes a flow cell having a mercury sensor, a light source and a light detector is provided. The mercury sensor includes a transparent substrate and a submonolayer of mercury absorbing nanoparticles, e.g., gold nanoparticles, on a surface of the substrate. Methods of determining whether mercury is present in a sample using the mercury sensors are also provided. The subject mercury detection systems and methods find use in a variety of different applications, including mercury detecting applications.

  11. Visible-light system for detecting doxorubicin contamination on skin and surfaces.

    PubMed

    Van Raalte, J; Rice, C; Moss, C E

    1990-05-01

    A portable system that uses fluorescence stimulated by visible light to identify doxorubicin contamination on skin and surfaces was studied. When activated by violet-blue light in the 465-nm range, doxorubicin fluoresces, emitting orange-red light in the 580-nm range. The light source to stimulate fluorescence was a slide projector with a filter to selectively pass short-wave (blue) visible light. Fluorescence was both observed visually with viewing spectacles and photographed. Solutions of doxorubicin in sterile 0.9% sodium chloride injection were prepared in nine standard concentrations ranging from 2 to 0.001 mg/mL. Droplets of each admixture were placed on stainless steel, laboratory coat cloth, pieces of latex examination glove, bench-top absorbent padding, and other materials on which antineoplastics might spill or leak. These materials then were stored for up to eight weeks and photographed weekly. The relative ability of water, household bleach, hydrogen peroxide solution, and soap solution to deactivate doxorubicin was also measured. Finally, this system was used to inspect the antineoplastic-drug preparation and administration areas of three outpatient cancer clinics for doxorubicin contamination. Doxorubicin fluorescence was easily detectable with viewing spectacles when a slide projector was used as the light source. The photographic method was sensitive for doxorubicin concentrations from 2.0 to 0.001 mg/mL. Immersion of study materials in bleach for one minute eliminated detectable fluorescence. Doxorubicin contamination is detectable for at least eight weeks in the ambient environment. Probable doxorubicin contamination was detected in two of the three clinics surveyed. A safe, portable system that uses fluorescence stimulated by visible light is a sensitive method for detecting doxorubicin on skin and surfaces.

  12. Systems and methods for detecting nuclear radiation in the presence of backgrounds

    DOEpatents

    Bross, Alan D.; Mellott, Kerry L.; Pla-Dalmau, Anna

    2005-06-21

    Systems and methods for the simultaneous detection and identification of radiation species, including neutrons, gammas/x-rays and minimum ionizing particles (MIPs). A plurality of rectangular and/or triangularly shaped radiation sensitive scintillators can be configured from a plurality of nano-sized particles, dopants and an extruded plastic material. A wavelength-shifting fiber can then be located within a central hole of each extruded scintillator, wherein the wavelength-shifting fiber absorbs scintillation light and re-emits the light at a longer wavelength, thereby piping the light to a photodetector whose response to the light indicates the presence of radiation The resulting method and system can simultaneously detect neutrons, gamma rays, x-rays and cosmic rays (MIPs) and identify each.

  13. The influence of the earth radiation on space target detection system

    NASA Astrophysics Data System (ADS)

    Su, Xiaofeng; Chen, FanSheng; Cuikun, .; Liuyan, .

    2017-05-01

    In the view of space remote sensing such as satellite detection space debris detection etc. visible band is usually used in order to have the all-weather detection capability, long wavelength infrared (LWIR) detection is also an important supplement. However, in the tow wave band, the earth can be a very strong interference source, especially in the dim target detecting. When the target is close to the earth, especially the LEO target, the background radiation of the earth will also enter into the baffle, and became the stray light through reflection, the stray light can reduce the signal to clutter ratio (SCR) of the target and make it difficult to be detected. In the visible band, the solar albedo by the earth is the main clutter source while in the LWIR band the radiation of the earth is the main clutter source. So, in this paper, we establish the energy transformation from the earth background radiation to the detection system to assess the effects of the stray light. Firstly, we discretize the surface of the earth to different unit, and using MODTRAN to calculate the radiation of the discrete point in different light and climate conditions, then, we integral all the radiation which can reach the baffle in the same observation angles to get the energy distribution, finally, according the target energy and the non-uniformity of the detector, we can calculate the design requirement of the system stray light suppression, which provides the design basis for the optical system.

  14. An Investigation of Laser Lighting Systems to Assist Aircraft

    DOT National Transportation Integrated Search

    1979-01-01

    A model for the visual detectability of narrow light beams was developed and used to evaluate the system performance of two laser lighting system configurations: (1) a laser VASI and (2) a crossed beam glide path indicator. Laboratory experiments con...

  15. Convolutional Neural Network-Based Shadow Detection in Images Using Visible Light Camera Sensor.

    PubMed

    Kim, Dong Seop; Arsalan, Muhammad; Park, Kang Ryoung

    2018-03-23

    Recent developments in intelligence surveillance camera systems have enabled more research on the detection, tracking, and recognition of humans. Such systems typically use visible light cameras and images, in which shadows make it difficult to detect and recognize the exact human area. Near-infrared (NIR) light cameras and thermal cameras are used to mitigate this problem. However, such instruments require a separate NIR illuminator, or are prohibitively expensive. Existing research on shadow detection in images captured by visible light cameras have utilized object and shadow color features for detection. Unfortunately, various environmental factors such as illumination change and brightness of background cause detection to be a difficult task. To overcome this problem, we propose a convolutional neural network-based shadow detection method. Experimental results with a database built from various outdoor surveillance camera environments, and from the context-aware vision using image-based active recognition (CAVIAR) open database, show that our method outperforms previous works.

  16. Convolutional Neural Network-Based Shadow Detection in Images Using Visible Light Camera Sensor

    PubMed Central

    Kim, Dong Seop; Arsalan, Muhammad; Park, Kang Ryoung

    2018-01-01

    Recent developments in intelligence surveillance camera systems have enabled more research on the detection, tracking, and recognition of humans. Such systems typically use visible light cameras and images, in which shadows make it difficult to detect and recognize the exact human area. Near-infrared (NIR) light cameras and thermal cameras are used to mitigate this problem. However, such instruments require a separate NIR illuminator, or are prohibitively expensive. Existing research on shadow detection in images captured by visible light cameras have utilized object and shadow color features for detection. Unfortunately, various environmental factors such as illumination change and brightness of background cause detection to be a difficult task. To overcome this problem, we propose a convolutional neural network-based shadow detection method. Experimental results with a database built from various outdoor surveillance camera environments, and from the context-aware vision using image-based active recognition (CAVIAR) open database, show that our method outperforms previous works. PMID:29570690

  17. Stray Light Analysis

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Based on a Small Business Innovation Research contract from the Jet Propulsion Laboratory, TracePro is state-of-the-art interactive software created by Lambda Research Corporation to detect stray light in optical systems. An image can be ruined by incidental light in an optical system. To maintain image excellence from an optical system, stray light must be detected and eliminated. TracePro accounts for absorption, specular reflection and refraction, scattering and aperture diffraction of light. Output from the software consists of spatial irradiance plots and angular radiance plots. Results can be viewed as contour maps or as ray histories in tabular form. TracePro is adept at modeling solids such as lenses, baffles, light pipes, integrating spheres, non-imaging concentrators, and complete illumination systems. The firm's customer base includes Lockheed Martin, Samsung Electronics and other manufacturing, optical, aerospace, and educational companies worldwide.

  18. Aerosol mass spectrometry systems and methods

    DOEpatents

    Fergenson, David P.; Gard, Eric E.

    2013-08-20

    A system according to one embodiment includes a particle accelerator that directs a succession of polydisperse aerosol particles along a predetermined particle path; multiple tracking lasers for generating beams of light across the particle path; an optical detector positioned adjacent the particle path for detecting impingement of the beams of light on individual particles; a desorption laser for generating a beam of desorbing light across the particle path about coaxial with a beam of light produced by one of the tracking lasers; and a controller, responsive to detection of a signal produced by the optical detector, that controls the desorption laser to generate the beam of desorbing light. Additional systems and methods are also disclosed.

  19. Smart LED lighting for major reductions in power and energy use for plant lighting in space

    NASA Astrophysics Data System (ADS)

    Poulet, Lucie

    Launching or resupplying food, oxygen, and water into space for long-duration, crewed missions to distant destinations, such as Mars, is currently impossible. Bioregenerative life-support systems under development worldwide involving photoautotrophic organisms offer a solution to the food dilemma. However, using traditional Earth-based lighting methods, growth of food crops consumes copious energy, and since sunlight will not always be available at different space destinations, efficient electric lighting solutions are badly needed to reduce the Equivalent System Mass (ESM) of life-support infrastructure to be launched and transported to future space destinations with sustainable human habitats. The scope of the present study was to demonstrate that using LEDs coupled to plant detection, and optimizing spectral and irradiance parameters of LED light, the model crop lettuce (Lactuca sativa L. cv. Waldmann's Green) can be grown with significantly lower electrical energy for plant lighting than using traditional lighting sources. Initial experiments aimed at adapting and troubleshooting a first-generation "smart" plant-detection system coupled to LED arrays resulted in optimizing the detection process for plant position and size to the limits of its current design. Lettuce crops were grown hydroponically in a growth chamber, where temperature, relative humidity, and CO2 level are controlled. Optimal irradiance and red/blue ratio of LED lighting were determined for plant growth during both lag and exponential phases of crop growth. Under optimizing conditions, the efficiency of the automatic detection system was integrated with LED switching and compared to a system in which all LEDs were energized throughout a crop-production cycle. At the end of each cropping cycle, plant fresh and dry weights and leaf area were measured and correlated with the amount of electrical energy (kWh) consumed. Preliminary results indicated that lettuce plants grown under optimizing conditions with red and blue LED lighting required 12 times less energy than with a traditional high-intensity discharge lighting system. This study paves the way for refinement of the smart lighting system and further, major reductions in ESM for space life-support systems and for ground-based controlled-environment agriculture. Project supported by NASA grant number NNX09AL99G.

  20. An Augmented Reality Endoscope System for Ureter Position Detection.

    PubMed

    Yu, Feng; Song, Enmin; Liu, Hong; Li, Yunlong; Zhu, Jun; Hung, Chih-Cheng

    2018-06-25

    Iatrogenic injury of ureter in the clinical operation may cause the serious complication and kidney damage. To avoid such a medical accident, it is necessary to provide the ureter position information to the doctor. For the detection of ureter position, an ureter position detection and display system with the augmented ris proposed to detect the ureter that is covered by human tissue. There are two key issues which should be considered in this new system. One is how to detect the covered ureter that cannot be captured by the electronic endoscope and the other is how to display the ureter position that provides stable and high-quality images. Simultaneously, any delayed processing of the system should disturb the surgery. The aided hardware detection method and target detection algorithms are proposed in this system. To mark the ureter position, a surface-lighting plastic optical fiber (POF) with the encoded light-emitting diode (LED) light is used to indicate the ureter position. The monochrome channel filtering algorithm (MCFA) is proposed to locate the ureter region more precisely. The ureter position is extracted using the proposed automatic region growing algorithm (ARGA) that utilizes the statistical information of the monochrome channel for the selection of growing seed point. In addition, according to the pulse signal of encoded light, the recognition of bright and dark frames based on the aided hardware (BDAH) is proposed to expedite the processing speed. Experimental results demonstrate that the proposed endoscope system can identify 92.04% ureter region in average.

  1. Research on photodiode detector-based spatial transient light detection and processing system

    NASA Astrophysics Data System (ADS)

    Liu, Meiying; Wang, Hu; Liu, Yang; Zhao, Hui; Nan, Meng

    2016-10-01

    In order to realize real-time signal identification and processing of spatial transient light, the features and the energy of the captured target light signal are first described and quantitatively calculated. Considering that the transient light signal has random occurrence, a short duration and an evident beginning and ending, a photodiode detector based spatial transient light detection and processing system is proposed and designed in this paper. This system has a large field of view and is used to realize non-imaging energy detection of random, transient and weak point target under complex background of spatial environment. Weak signal extraction under strong background is difficult. In this paper, considering that the background signal changes slowly and the target signal changes quickly, filter is adopted for signal's background subtraction. A variable speed sampling is realized by the way of sampling data points with a gradually increased interval. The two dilemmas that real-time processing of large amount of data and power consumption required by the large amount of data needed to be stored are solved. The test results with self-made simulative signal demonstrate the effectiveness of the design scheme. The practical system could be operated reliably. The detection and processing of the target signal under the strong sunlight background was realized. The results indicate that the system can realize real-time detection of target signal's characteristic waveform and monitor the system working parameters. The prototype design could be used in a variety of engineering applications.

  2. The research of adaptive-exposure on spot-detecting camera in ATP system

    NASA Astrophysics Data System (ADS)

    Qian, Feng; Jia, Jian-jun; Zhang, Liang; Wang, Jian-Yu

    2013-08-01

    High precision acquisition, tracking, pointing (ATP) system is one of the key techniques of laser communication. The spot-detecting camera is used to detect the direction of beacon in laser communication link, so that it can get the position information of communication terminal for ATP system. The positioning accuracy of camera decides the capability of laser communication system directly. So the spot-detecting camera in satellite-to-earth laser communication ATP systems needs high precision on target detection. The positioning accuracy of cameras should be better than +/-1μ rad . The spot-detecting cameras usually adopt centroid algorithm to get the position information of light spot on detectors. When the intensity of beacon is moderate, calculation results of centroid algorithm will be precise. But the intensity of beacon changes greatly during communication for distance, atmospheric scintillation, weather etc. The output signal of detector will be insufficient when the camera underexposes to beacon because of low light intensity. On the other hand, the output signal of detector will be saturated when the camera overexposes to beacon because of high light intensity. The calculation accuracy of centroid algorithm becomes worse if the spot-detecting camera underexposes or overexposes, and then the positioning accuracy of camera will be reduced obviously. In order to improve the accuracy, space-based cameras should regulate exposure time in real time according to light intensity. The algorithm of adaptive-exposure technique for spot-detecting camera based on metal-oxide-semiconductor (CMOS) detector is analyzed. According to analytic results, a CMOS camera in space-based laser communication system is described, which utilizes the algorithm of adaptive-exposure to adapting exposure time. Test results from imaging experiment system formed verify the design. Experimental results prove that this design can restrain the reduction of positioning accuracy for the change of light intensity. So the camera can keep stable and high positioning accuracy during communication.

  3. Systems and Methods for Correcting Optical Reflectance Measurements

    NASA Technical Reports Server (NTRS)

    Yang, Ye (Inventor); Shear, Michael A. (Inventor); Soller, Babs R. (Inventor); Soyemi, Olusola O. (Inventor)

    2014-01-01

    We disclose measurement systems and methods for measuring analytes in target regions of samples that also include features overlying the target regions. The systems include: (a) a light source; (b) a detection system; (c) a set of at least first, second, and third light ports which transmit light from the light source to a sample and receive and direct light reflected from the sample to the detection system, generating a first set of data including information corresponding to both an internal target within the sample and features overlying the internal target, and a second set of data including information corresponding to features overlying the internal target; and (d) a processor configured to remove information characteristic of the overlying features from the first set of data using the first and second sets of data to produce corrected information representing the internal target.

  4. Systems and methods for correcting optical reflectance measurements

    NASA Technical Reports Server (NTRS)

    Yang, Ye (Inventor); Soller, Babs R. (Inventor); Soyemi, Olusola O. (Inventor); Shear, Michael A. (Inventor)

    2009-01-01

    We disclose measurement systems and methods for measuring analytes in target regions of samples that also include features overlying the target regions. The systems include: (a) a light source; (b) a detection system; (c) a set of at least first, second, and third light ports which transmit light from the light source to a sample and receive and direct light reflected from the sample to the detection system, generating a first set of data including information corresponding to both an internal target within the sample and features overlying the internal target, and a second set of data including information corresponding to features overlying the internal target; and (d) a processor configured to remove information characteristic of the overlying features from the first set of data using the first and second sets of data to produce corrected information representing the internal target.

  5. Strawberry Maturity Neural Network Detectng System Based on Genetic Algorithm

    NASA Astrophysics Data System (ADS)

    Xu, Liming

    The quick and non-detective detection of agriculture product is one of the measures to increase the precision and productivity of harvesting and grading. Having analyzed H frequency of different maturities in different light intensities, the results show that H frequency for the same maturity has little influence in different light intensities; Under the same light intensity, three strawberry maturities are changing in order. After having confirmed the H frequency section to distinguish the different strawberry maturity, the triplelayer feed-forward neural network system to detect strawberry maturity was designed by using genetic algorithm. The test results show that the detecting precision ratio is 91.7%, it takes 160ms to distinguish one strawberry. Therefore, the online non-detective detecting the strawberry maturity could be realized.

  6. Laser-induced photo emission detection: data acquisition based on light intensity counting

    NASA Astrophysics Data System (ADS)

    Yulianto, N.; Yudasari, N.; Putri, K. Y.

    2017-04-01

    Laser Induced Breakdown Detection (LIBD) is one of the quantification techniques for colloids. There are two ways of detection in LIBD: optical detection and acoustic detection. LIBD is based on the detection of plasma emission due to the interaction between particle and laser beam. In this research, the changing of light intensity during plasma formations was detected by a photodiode sensor. A photo emission data acquisition system was built to collect and transform them into digital counts. The real-time system used data acquisition device National Instrument DAQ 6009 and LABVIEW software. The system has been tested on distilled water and tap water samples. The result showed 99.8% accuracy by using counting technique in comparison to the acoustic detection with sample rate of 10 Hz, thus the acquisition system can be applied as an alternative method to the existing LIBD acquisition system.

  7. An Automated Flying-Insect-Detection System

    NASA Technical Reports Server (NTRS)

    Vann, Timi; Andrews, Jane C.; Howell, Dane; Ryan, Robert

    2005-01-01

    An automated flying-insect-detection system (AFIDS) was developed as a proof-of-concept instrument for real-time detection and identification of flying insects. This type of system has use in public health and homeland security decision support, agriculture and military pest management, and/or entomological research. Insects are first lured into the AFIDS integrated sphere by insect attractants. Once inside the sphere, the insect's wing beats cause alterations in light intensity that is detected by a photoelectric sensor. Following detection, the insects are encouraged (with the use of a small fan) to move out of the sphere and into a designated insect trap where they are held for taxonomic identification or serological testing. The acquired electronic wing beat signatures are preprocessed (Fourier transformed) in real-time to display a periodic signal. These signals are sent to the end user where they are graphically displayed. All AFIDS data are pre-processed in the field with the use of a laptop computer equipped with LABVIEW. The AFIDS software can be programmed to run continuously or at specific time intervals when insects are prevalent. A special DC-restored transimpedance amplifier reduces the contributions of low-frequency background light signals, and affords approximately two orders of magnitude greater AC gain than conventional amplifiers. This greatly increases the signal-to-noise ratio and enables the detection of small changes in light intensity. The AFIDS light source consists of high-intensity Al GaInP light-emitting diodes (LEDs). The AFIDS circuitry minimizes brightness fluctuations in the LEDs and when integrated with an integrating sphere, creates a diffuse uniform light field. The insect wing beats isotropically scatter the diffuse light in the sphere and create wing beat signatures that are detected by the sensor. This configuration minimizes variations in signal associated with insect flight orientation.

  8. The system of high accuracy UV spectral radiation system

    NASA Astrophysics Data System (ADS)

    Lin, Guan-yu; Yu, Lei; Xu, Dian; Cao, Dian-sheng; Yu, Yu-Xiang

    2016-10-01

    UV spectral radiation detecting and visible observation telescope is designed by the coaxial optical. In order to decrease due to the incident light polarization effect, and improve the detection precision, polarizer need to be used in the light path. Four pieces of quartz of high Precision UV radiation depolarizer retarder stack together is placed in front of Seya namioka dispersion unit. The coherent detection principle of modulation of light signal and the reference signal multiplied processing, increase the phase sensitive detector can be adjustment function, ensure the UV spectral radiation detection stability. A lock-in amplifier is used in the electrical system to advance the accuracy of measurement. To ensure the precision measurement detected, the phase-sensitive detector function can be adjustable. the output value is not more than 10mV before each measurement, so it can be ensured that the stability of the measured radiation spectrum is less than 1 percent.

  9. Detecting an Extended Light Source through a Lens

    ERIC Educational Resources Information Center

    Litaker, E. T.; Machacek, J. R.; Gay, T. J.

    2011-01-01

    We present a Monte Carlo simulation of a cylindrical luminescent volume and a typical lens-detector system. The results of this simulation yield a graphically simple picture of the regions within the cylindrical volume from which this system detects light. Because the cylindrical volume permits large angles of incidence, we use a modification of…

  10. Waveguide detection of right-angle-scattered light in flow cytometry

    DOEpatents

    Mariella, Jr., Raymond P.

    2000-01-01

    A transparent flow cell is used as an index-guided optical waveguide. A detector for the flow cell but not the liquid stream detects the Right-Angle-Scattered (RAS) Light exiting from one end of the flow cell. The detector(s) could view the trapped RAS light from the flow cell either directly or through intermediate optical light guides. If the light exits one end of the flow cell, then the other end of the flow cell can be given a high-reflectivity coating to approximately double the amount of light collected. This system is more robust in its alignment than the traditional flow cytometry systems which use imaging optics, such as microscope objectives.

  11. The cervical cancer detection system based on an endoscopic rotary probe

    NASA Astrophysics Data System (ADS)

    Yang, Yanshuang; Hou, Qiang; Zhao, Huijuan; Qin, Zhuanping; Gao, Feng

    2012-03-01

    To acquire the optical diffuse tomographic image of the cervix, a novel endoscopic rotary probe is designed and the frequency domain measurement system is developed. The finite element method and Gauss-Newton method are proposed to reconstruct the image of the phantom. In the optical diffuse tomographic imaging of the cervix, an endoscopic probe is needed and the detection of light at different separation to the irradiation spot is necessary. To simplify the system, only two optical fibers are adopted for light irradiation and collection, respectively. Two small stepper motors are employed to control the rotation of the incident fiber and the detection fiber, respectively. For one position of source fiber, the position of the detection fiber is changed from -61.875° to -50.625° and 50.625° to 61.875° to the source fiber, respectively. Then, the position of the source fiber is changed to another preconcerted position, which deviates the precious source position in an angle of 11.25°, and the detection fiber rotates within the above angles. To acquire the efficient irradiation and collection of the light, a gradient-index (GRIN) lens is connected at the head of the optical fiber. The other end of the GRIN lens is cut to 45°. With this design, light from optical fiber is reflected to the cervix wall, which is perpendicular to the optical fiber or vice versa. Considering the cervical size, the external diameter of the endoscopic probe is made to 20mm. A frequency domain (FD) near-infrared diffuse system is developed aiming at the detection of early cervical cancer, which modulates the light intensity in radio frequency and measures the amplitude attenuation and the phase delay of the diffused light using heterodyne detection. Phantom experiment results demonstrate that the endoscopic rotary scan probe and the system perform well in the endoscopic measurement.

  12. A compact imaging spectroscopic system for biomolecular detections on plasmonic chips.

    PubMed

    Lo, Shu-Cheng; Lin, En-Hung; Wei, Pei-Kuen; Tsai, Wan-Shao

    2016-10-17

    In this study, we demonstrate a compact imaging spectroscopic system for high-throughput detection of biomolecular interactions on plasmonic chips, based on a curved grating as the key element of light diffraction and light focusing. Both the curved grating and the plasmonic chips are fabricated on flexible plastic substrates using a gas-assisted thermal-embossing method. A fiber-coupled broadband light source and a camera are included in the system. Spectral resolution within 1 nm is achieved in sensing environmental index solutions and protein bindings. The detected sensitivities of the plasmonic chip are comparable with a commercial spectrometer. An extra one-dimensional scanning stage enables high-throughput detection of protein binding on a designed plasmonic chip consisting of several nanoslit arrays with different periods. The detected resonance wavelengths match well with the grating equation under an air environment. Wavelength shifts between 1 and 9 nm are detected for antigens of various concentrations binding with antibodies. A simple, mass-productive and cost-effective method has been demonstrated on the imaging spectroscopic system for real-time, label-free, highly sensitive and high-throughput screening of biomolecular interactions.

  13. Detection of light-matter interaction in the weak-coupling regime by quantum light

    NASA Astrophysics Data System (ADS)

    Bin, Qian; Lü, Xin-You; Zheng, Li-Li; Bin, Shang-Wu; Wu, Ying

    2018-04-01

    "Mollow spectroscopy" is a photon statistics spectroscopy, obtained by scanning the quantum light scattered from a source system. Here, we apply this technique to detect the weak light-matter interaction between the cavity and atom (or a mechanical oscillator) when the strong system dissipation is included. We find that the weak interaction can be measured with high accuracy when exciting the target cavity by quantum light scattered from the source halfway between the central peak and each side peak. This originally comes from the strong correlation of the injected quantum photons. In principle, our proposal can be applied into the normal cavity quantum electrodynamics system described by the Jaynes-Cummings model and an optomechanical system. Furthermore, it is state of the art for experiment even when the interaction strength is reduced to a very small value.

  14. White Light Heterodyne Interferometry SNR

    DTIC Science & Technology

    2015-04-09

    interferometers in the visible- and near-IR, where shot - noise -limited detectors are available. In the LWIR, the advantage of a direct detection...wavebands where shot - noise -limited detection is possible with direct detection systems, the relationship changes in the mid-wave infrared (MWIR) and...flux, without either having to split the light N – 1 ways or take the extra shot - noise penalty from Fizeau beam combining light from all apertures

  15. SiPM electro-optical detection system noise suppression method

    NASA Astrophysics Data System (ADS)

    Bi, Xiangli; Yang, Suhui; Hu, Tao; Song, Yiheng

    2014-11-01

    In this paper, the single photon detection principle of Silicon Photomultipliers (SiPM) device is introduced. The main noise factors that infect the sensitivity of the electro-optical detection system are analyzed, including background light noise, detector dark noise, preamplifier noise and signal light noise etc. The Optical, electrical and thermodynamic methods are used to suppress the SiPM electro-optical detection system noise, which improved the response sensitivity of the detector. Using SiPM optoelectronic detector with a even high sensitivity, together with small field large aperture optical system, high cutoff narrow bandwidth filters, low-noise operational amplifier circuit, the modular design of functional circuit, semiconductor refrigeration technology, greatly improved the sensitivity of optical detection system, reduced system noise and achieved long-range detection of weak laser radiation signal. Theoretical analysis and experimental results show that the proposed methods are reasonable and efficient.

  16. Sample collection system for gel electrophoresis

    DOEpatents

    Olivares, Jose A.; Stark, Peter C.; Dunbar, John M.; Hill, Karen K.; Kuske, Cheryl R.; Roybal, Gustavo

    2004-09-21

    An automatic sample collection system for use with an electrophoretic slab gel system is presented. The collection system can be used with a slab gel have one or more lanes. A detector is used to detect particle bands on the slab gel within a detection zone. Such detectors may use a laser to excite fluorescently labeled particles. The fluorescent light emitted from the excited particles is transmitted to low-level light detection electronics. Upon the detection of a particle of interest within the detection zone, a syringe pump is activated, sending a stream of buffer solution across the lane of the slab gel. The buffer solution collects the sample of interest and carries it through a collection port into a sample collection vial.

  17. Sensitivity enhancement of fluorescence detection in CE by coupling and conducting excitation light with tapered optical fiber.

    PubMed

    Yang, Xiupei; Huo, Feng; Yuan, Hongyan; Zhang, Bo; Xiao, Dan; Choi, Martin M F

    2011-01-01

    This paper reports the enhancement of sensitivity of detection for in-column fiber optic-induced fluorescence detection system in CE by tapered optical fiber (TOF). Two types of optical fiber, TOF and conventional cylindrical optical fiber (COF), were employed to construct the CE (TOF-CE and COF-CE) and were compared for sensitivity to riboflavin (RF). The fluorescence intensities from a RF sample with excitation light sources and fibers at various coupling angles were investigated. The fluorescence signal from TOF-CE was ca. ten times that of COF-CE. In addition, the detection performance of four excitation light source-fiber configurations including Laser-TOF, Laser-COF, LED-TOF, and LED-COF were compared. The LODs for RF were 0.21, 0.82, 0.80, and 7.5 nM, respectively, for the four excitation light source-fiber configurations. The results demonstrate that the sensitivity obtained by LED-TOF is close to that of Laser-COF. Both Laser-TOF and LED-TOF can greatly improve the sensitivity of detection in CE. TOF has the major attribute of collecting and focusing the excitation light intensity. Thus, the sensitivity obtained by LED-TOF without focusing lens is just same as that of LED-COF with a focusing lens. This demonstrates that the CE system can be further simplified by eliminating the focusing lens for excitation light. LED-TOF-CE and LED-COF-CE system were applied to the separation and determination of RF in real sample (green tea), respectively. The tapered fiber optic-induced fluorescence detection system in CE is an ideal tool for trace analysis. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Multiple capillary biochemical analyzer

    DOEpatents

    Dovichi, N.J.; Zhang, J.Z.

    1995-08-08

    A multiple capillary analyzer allows detection of light from multiple capillaries with a reduced number of interfaces through which light must pass in detecting light emitted from a sample being analyzed, using a modified sheath flow cuvette. A linear or rectangular array of capillaries is introduced into a rectangular flow chamber. Sheath fluid draws individual sample streams through the cuvette. The capillaries are closely and evenly spaced and held by a transparent retainer in a fixed position in relation to an optical detection system. Collimated sample excitation radiation is applied simultaneously across the ends of the capillaries in the retainer. Light emitted from the excited sample is detected by the optical detection system. The retainer is provided by a transparent chamber having inward slanting end walls. The capillaries are wedged into the chamber. One sideways dimension of the chamber is equal to the diameter of the capillaries and one end to end dimension varies from, at the top of the chamber, slightly greater than the sum of the diameters of the capillaries to, at the bottom of the chamber, slightly smaller than the sum of the diameters of the capillaries. The optical system utilizes optic fibers to deliver light to individual photodetectors, one for each capillary tube. A filter or wavelength division demultiplexer may be used for isolating fluorescence at particular bands. 21 figs.

  19. Multiple capillary biochemical analyzer

    DOEpatents

    Dovichi, Norman J.; Zhang, Jian Z.

    1995-01-01

    A multiple capillary analyzer allows detection of light from multiple capillaries with a reduced number of interfaces through which light must pass in detecting light emitted from a sample being analyzed, using a modified sheath flow cuvette. A linear or rectangular array of capillaries is introduced into a rectangular flow chamber. Sheath fluid draws individual sample streams through the cuvette. The capillaries are closely and evenly spaced and held by a transparent retainer in a fixed position in relation to an optical detection system. Collimated sample excitation radiation is applied simultaneously across the ends of the capillaries in the retainer. Light emitted from the excited sample is detected by the optical detection system. The retainer is provided by a transparent chamber having inward slanting end walls. The capillaries are wedged into the chamber. One sideways dimension of the chamber is equal to the diameter of the capillaries and one end to end dimension varies from, at the top of the chamber, slightly greater than the sum of the diameters of the capillaries to, at the bottom of the chamber, slightly smaller than the sum of the diameters of the capillaries. The optical system utilizes optic fibres to deliver light to individual photodetectors, one for each capillary tube. A filter or wavelength division demultiplexer may be used for isolating fluorescence at particular bands.

  20. Evaluation of video detection systems, volume 2 : effects of illumination conditions in the performance of video detection systems.

    DOT National Transportation Integrated Search

    2009-05-01

    The evaluation of three Video Detection Systems (VDS) at an instrumented signalized intersection in Rantoul : Illinois, at both stop bar and advance detection zones, was performed under a wide range of lighting and : weather conditions. The evaluated...

  1. Traffic Sign Recognition with Invariance to Lighting in Dual-Focal Active Camera System

    NASA Astrophysics Data System (ADS)

    Gu, Yanlei; Panahpour Tehrani, Mehrdad; Yendo, Tomohiro; Fujii, Toshiaki; Tanimoto, Masayuki

    In this paper, we present an automatic vision-based traffic sign recognition system, which can detect and classify traffic signs at long distance under different lighting conditions. To realize this purpose, the traffic sign recognition is developed in an originally proposed dual-focal active camera system. In this system, a telephoto camera is equipped as an assistant of a wide angle camera. The telephoto camera can capture a high accuracy image for an object of interest in the view field of the wide angle camera. The image from the telephoto camera provides enough information for recognition when the accuracy of traffic sign is low from the wide angle camera. In the proposed system, the traffic sign detection and classification are processed separately for different images from the wide angle camera and telephoto camera. Besides, in order to detect traffic sign from complex background in different lighting conditions, we propose a type of color transformation which is invariant to light changing. This color transformation is conducted to highlight the pattern of traffic signs by reducing the complexity of background. Based on the color transformation, a multi-resolution detector with cascade mode is trained and used to locate traffic signs at low resolution in the image from the wide angle camera. After detection, the system actively captures a high accuracy image of each detected traffic sign by controlling the direction and exposure time of the telephoto camera based on the information from the wide angle camera. Moreover, in classification, a hierarchical classifier is constructed and used to recognize the detected traffic signs in the high accuracy image from the telephoto camera. Finally, based on the proposed system, a set of experiments in the domain of traffic sign recognition is presented. The experimental results demonstrate that the proposed system can effectively recognize traffic signs at low resolution in different lighting conditions.

  2. Feasibility Study of an Optical Caustic Plasmonic Light Scattering Sensor for Human Serum Anti-Dengue Protein E Antibody Detection

    PubMed Central

    García, Antonio A.; Pirez-Gomez, Miguel A.; Pech-Pacheco, José L.; Mendez-Galvan, Jorge F.; Machain-Williams, Carlos; Talavera-Aguilar, Lourdes; Espinosa-Carrillo, José H.; Duarte-Villaseñor, Miriam M.; Be-Ortiz, Christian; Espinosa-de los Monteros, Luz E.; Castillo-Pacheco, Ariel; Garcia-Rejon, Julian E.

    2017-01-01

    Antibody detection and accurate diagnosis of tropical diseases is essential to help prevent the spread of disease. However, most detection methods lack cost-effectiveness and field portability, which are essential features for achieving diagnosis in a timely manner. To address this, 3D-printed oblate spheroid sample chambers were fabricated to measure green light scattering of gold nanoparticles using an optical caustic focus to detect antibodies. Scattering signals of 20–200 nm gold nanoparticles using a green laser were compared to green light emitting diode (LED) light source signals and to Mie theory. The change in signal from 60 to 120 nm decreased in the order of Mie Theory > optical caustic scattering > 90° scattering. These results suggested that conjugating 60 nm gold nanoparticles and using an optical caustic system to detect plasmonic light scattering, would result in a sensitive test for detecting human antibodies in serum. Therefore, we studied the light scattering response of conjugated gold nanoparticles exposed to different concentrations of anti-protein E antibody, and a feasibility study of 10 human serum samples using dot blot and a handheld optical caustic-based sensor device. The overall agreement between detection methods suggests that the new sensor concept shows promise to detect gold nanoparticle aggregation in a homogeneous assay. Further testing and protocol optimization is needed to draw conclusions on the positive and negative predictive values for this new testing system. PMID:28817080

  3. Fly Ear Inspired Miniature Acoustic Sensors for Detection and Localization

    DTIC Science & Technology

    2011-07-31

    Micro-Opto-Electro-Mechnical-System ( MOEMS ) sensor platform that is capable of integrating multiplexed Fabry-Perot (FP) interferometer based sensors. A...on a single MOEMS chip is shown in Figure 8. Light from a low coherence light source with a coherence length Lc is first sent to the reference...towards developing a low coherence interferometer based MOEMS detection system. An optical Micro-Electro-Mechanical-System (MEMS) sensor platform was

  4. Oxygen detection using the laser diode absorption technique

    NASA Technical Reports Server (NTRS)

    Disimile, P. J.; Fox, C. W.

    1991-01-01

    Accurate measurement of the concentration and flow rate of gaseous oxygen is becoming of greater importance. The detection technique presented is based on the principal of light absorption by the Oxygen A-Band. Oxygen molecules have characteristics which attenuate radiation in the 759-770 nm wavelength range. With an ability to measure changes in the relative light transmission to less than 0.01 percent, a sensitive optical gas detection system was configured. This system is smaller in size and light in weight, has low energy requirements and has a rapid response time. In this research program, the application of temperature tuning laser diodes and their ability to be wavelength shifted to a selected absorption spectral peak has allowed concentrations as low as 1300 ppm to be detected.

  5. Multicolor Fluorescence Detection for Droplet Microfluidics Using Optical Fibers

    PubMed Central

    Cole, Russell H.; Gartner, Zev J.; Abate, Adam R.

    2016-01-01

    Fluorescence assays are the most common readouts used in droplet microfluidics due to their bright signals and fast time response. Applications such as multiplex assays, enzyme evolution, and molecular biology enhanced cell sorting require the detection of two or more colors of fluorescence. Standard multicolor detection systems that couple free space lasers to epifluorescence microscopes are bulky, expensive, and difficult to maintain. In this paper, we describe a scheme to perform multicolor detection by exciting discrete regions of a microfluidic channel with lasers coupled to optical fibers. Emitted light is collected by an optical fiber coupled to a single photodetector. Because the excitation occurs at different spatial locations, the identity of emitted light can be encoded as a temporal shift, eliminating the need for more complicated light filtering schemes. The system has been used to detect droplet populations containing four unique combinations of dyes and to detect sub-nanomolar concentrations of fluorescein. PMID:27214249

  6. Research on the detection system of liquid concentration base on birefringence light transmission method

    NASA Astrophysics Data System (ADS)

    Li, Tianze; Zhang, Xia; Hou, Luan; Jiang, Chuan

    2010-10-01

    The characteristics of the beam transmitting in the optical fiber and the liquid medium are analyzed in this paper. On this basis, a new type of semiconductor optical position sensitive detector is used for a receiving device, a light transmission method of birefringence is presented,and a set of opto-electrical detection system which is applied to detect liquid concentration is designed. The system is mainly composed of semiconductor lasers,optical systems, Psd signal conditioning circuit, Single-chip System, A/D conversion circuit and display circuit. Through theoretical analysis and experimental simulations, the accuracy of this system has been verified. Some main factors affecting the test results are analyzed detailedly in this paper. The experiments show that the temperature drift and the light intensity have a very small impact on this system. The system has some advantages, such as the simple structure, high sensitivity, good stability, fast response time, high degree of automation, and so on. It also can achieve the real-time detection of liquid concentration conveniently and accurately. The system can be widely applied in chemical, food, pharmacy and many other industries. It has broad prospects of application.

  7. Double-cladding-fiber-based detection system for intravascular mapping of fluorescent molecular probes

    NASA Astrophysics Data System (ADS)

    Razansky, R. Nika; Rozental, Amir; Mueller, Mathias S.; Deliolanis, Nikolaos; Jaffer, Farouc A.; Koch, Alexander W.; Ntziachristos, Vasilis

    2011-03-01

    Early detection of high-risk coronary atherosclerosis remains an unmet clinical challenge. We have previously demonstrated a near-infrared fluorescence catheter system for two-dimensional intravascular detection of fluorescence molecular probes [1]. In this work we improve the system performance by introducing a novel high resolution sensor. The main challenge of the intravascular sensor is to provide a highly focused spot at an application relevant distance on one hand and a highly efficient collection of emitted light on the other. We suggest employing a double cladding optical fiber (DCF) in combination with focusing optics to provide a sensor with both highly focused excitation light and highly efficient fluorescent light collection. The excitation laser is coupled into the single mode core of DCF and guided through a focusing element and a right angle prism. The resulting side-fired beam exhibits a small spot diameter (50 μm) throughout a distance of up to 2 mm from the sensor. This is the distance of interest for intravascular coronary imaging application, determined by an average human coronary artery diameter. At the blood vessel wall, an activatable fluorescence molecular probe is excited in the diseased lesions. Next light of slightly shifted wavelength emits only in the places of the inflammations, associated with dangerous plaques [2]. The emitted light is collected by the cladding of the DCF, with a large collection angle (NA=0.4). The doublecladding acts as multimodal fiber and guides the collected light to the photo detection elements. The sensor automatically rotates and pulled-back, while each scanned point is mapped according to the amount of detected fluorescent emission. The resulting map of fluorescence activity helps to associate the atherosclerotic plaques with the inflammation process. The presented detection system is a valuable tool in the intravascular plaque detection and can help to differentiate the atherosclerotic plaques based on their biological activity, identify the ones that prone to rupture and therefore require more medical attention.

  8. 46 CFR 28.355 - Main source of electrical power.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... auxiliaries and controls; (2) Interior lighting; (3) Steering systems; (4) Communication systems; (5) Navigation equipment and navigation lights; (6) Fire protection or detection equipment; (7) Bilge pumps; or...

  9. 46 CFR 28.355 - Main source of electrical power.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... auxiliaries and controls; (2) Interior lighting; (3) Steering systems; (4) Communication systems; (5) Navigation equipment and navigation lights; (6) Fire protection or detection equipment; (7) Bilge pumps; or...

  10. 46 CFR 28.850 - Main source of electrical power.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... controls; (2) Interior lighting; (3) Steering systems; (4) Communication systems; (5) Navigation equipment and navigation lights; (6) Fire protection or detection equipment; (7) Bilge pumps; and (8) General...

  11. 46 CFR 28.850 - Main source of electrical power.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... controls; (2) Interior lighting; (3) Steering systems; (4) Communication systems; (5) Navigation equipment and navigation lights; (6) Fire protection or detection equipment; (7) Bilge pumps; and (8) General...

  12. 46 CFR 28.355 - Main source of electrical power.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... auxiliaries and controls; (2) Interior lighting; (3) Steering systems; (4) Communication systems; (5) Navigation equipment and navigation lights; (6) Fire protection or detection equipment; (7) Bilge pumps; or...

  13. 46 CFR 28.850 - Main source of electrical power.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... controls; (2) Interior lighting; (3) Steering systems; (4) Communication systems; (5) Navigation equipment and navigation lights; (6) Fire protection or detection equipment; (7) Bilge pumps; and (8) General...

  14. 46 CFR 28.355 - Main source of electrical power.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... auxiliaries and controls; (2) Interior lighting; (3) Steering systems; (4) Communication systems; (5) Navigation equipment and navigation lights; (6) Fire protection or detection equipment; (7) Bilge pumps; or...

  15. 46 CFR 28.850 - Main source of electrical power.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... controls; (2) Interior lighting; (3) Steering systems; (4) Communication systems; (5) Navigation equipment and navigation lights; (6) Fire protection or detection equipment; (7) Bilge pumps; and (8) General...

  16. Red-light excitation of protoporphyrin IX fluorescence for subsurface tumor detection.

    PubMed

    Roberts, David W; Olson, Jonathan D; Evans, Linton T; Kolste, Kolbein K; Kanick, Stephen C; Fan, Xiaoyao; Bravo, Jaime J; Wilson, Brian C; Leblond, Frederic; Marois, Mikael; Paulsen, Keith D

    2018-06-01

    OBJECTIVE The objective of this study was to detect 5-aminolevulinic acid (ALA)-induced tumor fluorescence from glioma below the surface of the surgical field by using red-light illumination. METHODS To overcome the shallow tissue penetration of blue light, which maximally excites the ALA-induced fluorophore protoporphyrin IX (PpIX) but is also strongly absorbed by hemoglobin and oxyhemoglobin, a system was developed to illuminate the surgical field with red light (620-640 nm) matching a secondary, smaller absorption peak of PpIX and detecting the fluorescence emission through a 650-nm longpass filter. This wide-field spectroscopic imaging system was used in conjunction with conventional blue-light fluorescence for comparison in 29 patients undergoing craniotomy for resection of high-grade glioma, low-grade glioma, meningioma, or metastasis. RESULTS Although, as expected, red-light excitation is less sensitive to PpIX in exposed tumor, it did reveal tumor at a depth up to 5 mm below the resection bed in 22 of 24 patients who also exhibited PpIX fluorescence under blue-light excitation during the course of surgery. CONCLUSIONS Red-light excitation of tumor-associated PpIX fluorescence below the surface of the surgical field can be achieved intraoperatively and enables detection of subsurface tumor that is not visualized under conventional blue-light excitation. Clinical trial registration no.: NCT02191488 (clinicaltrials.gov).

  17. Optical detection system for MEMS-type pressure sensor

    NASA Astrophysics Data System (ADS)

    Sareło, K.; Górecka-Drzazga, A.; Dziuban, J. A.

    2015-07-01

    In this paper a special optical detection system designed for a MEMS-type (micro-electro-mechanical system) silicon pressure sensor is presented. The main part of the optical system—a detection unit with a perforated membrane—is bonded to the silicon sensor, and placed in a measuring system. An external light source illuminates the membrane of the pressure sensor. Owing to the light reflected from the deflected membrane sensor, the optical pattern consisting of light points is visible, and pressure can be estimated. The optical detection unit (20   ×   20   ×   20.4 mm3) is fabricated using microengineering techniques. Its dimensions are adjusted to the dimensions of the pressure sensor (5   ×   5 mm2 silicon membrane). Preliminary tests of the optical detection unit integrated with the silicon pressure sensor are carried out. For the membrane sensor from 15 to 60 µm thick, a repeatable detection of the differential pressure in the range of 0 to 280 kPa is achieved. The presented optical microsystem is especially suitable for the pressure measurements in a high radiation environment.

  18. Laser beam monitoring system

    DOEpatents

    Weil, Bradley S.; Wetherington, Jr., Grady R.

    1985-01-01

    Laser beam monitoring systems include laser-transparent plates set at an angle to the laser beam passing therethrough and light sensor for detecting light reflected from an object on which the laser beam impinges.

  19. Laser beam monitoring system

    DOEpatents

    Weil, B.S.; Wetherington, G.R. Jr.

    Laser beam monitoring systems include laser-transparent plates set at an angle to the laser beam passing therethrough and light sensor for detecting light reflected from an object on which the laser beam impinges.

  20. Backscatter absorption gas imaging systems and light sources therefore

    DOEpatents

    Kulp, Thomas Jan [Livermore, CA; Kliner, Dahv A. V. [San Ramon, CA; Sommers, Ricky [Oakley, CA; Goers, Uta-Barbara [Campbell, NY; Armstrong, Karla M [Livermore, CA

    2006-12-19

    The location of gases that are not visible to the unaided human eye can be determined using tuned light sources that spectroscopically probe the gases and cameras that can provide images corresponding to the absorption of the gases. The present invention is a light source for a backscatter absorption gas imaging (BAGI) system, and a light source incorporating the light source, that can be used to remotely detect and produce images of "invisible" gases. The inventive light source has a light producing element, an optical amplifier, and an optical parametric oscillator to generate wavelength tunable light in the IR. By using a multi-mode light source and an amplifier that operates using 915 nm pump sources, the power consumption of the light source is reduced to a level that can be operated by batteries for long periods of time. In addition, the light source is tunable over the absorption bands of many hydrocarbons, making it useful for detecting hazardous gases.

  1. Traffic light detection and intersection crossing using mobile computer vision

    NASA Astrophysics Data System (ADS)

    Grewei, Lynne; Lagali, Christopher

    2017-05-01

    The solution for Intersection Detection and Crossing to support the development of blindBike an assisted biking system for the visually impaired is discussed. Traffic light detection and intersection crossing are key needs in the task of biking. These problems are tackled through the use of mobile computer vision, in the form of a mobile application on an Android phone. This research builds on previous Traffic Light detection algorithms with a focus on efficiency and compatibility on a resource-limited platform. Light detection is achieved through blob detection algorithms utilizing training data to detect patterns of Red, Green and Yellow in complex real world scenarios where multiple lights may be present. Also, issues of obscurity and scale are addressed. Safe Intersection crossing in blindBike is also discussed. This module takes a conservative "assistive" technology approach. To achieve this blindBike use's not only the Android device but, an external bike cadence Bluetooth/Ant enabled sensor. Real world testing results are given and future work is discussed.

  2. Systems and methods for detecting neutrons

    DOEpatents

    Bross, Alan D.; Mellott, Kerry L.; Pla-Dalmau, Anna

    2005-08-09

    Systems and methods for detecting neutrons. One or more neutron-sensitive scintillators can be configured from a plurality of nano-sized particles, dopants and an extruded plastic material, such as polystyrene. The nano-sized particles can be compounded into the extruded plastic material with at least one dopant that permits the plastic material to scintillate. One or more plastic light collectors can be associated with a neutron-sensitive scintillator, such that the plastic light collector includes a central hole thereof. A wavelength-shifting fiber can then be located within the hole. The wavelength shifting (WLS) fiber absorbs scintillation light having a wavelength thereof and re-emits the light at a longer wavelength.

  3. Permeation absorption sampler with multiple detection

    DOEpatents

    Zaromb, Solomon

    1990-01-01

    A system for detecting analytes in air or aqueous systems includes a permeation absorption preconcentrator sampler for the analytes and analyte detectors. The preconcentrator has an inner fluid-permeable container into which a charge of analyte-sorbing liquid is intermittently injected, and a fluid-impermeable outer container. The sample is passed through the outer container and around the inner container for trapping and preconcentrating the analyte in the sorbing liquid. The analyte can be detected photometrically by injecting with the sorbing material a reagent which reacts with the analyte to produce a characteristic color or fluorescence which is detected by illuminating the contents of the inner container with a light source and measuring the absorbed or emitted light, or by producing a characteristic chemiluminescence which can be detected by a suitable light sensor. The analyte can also be detected amperometrically. Multiple inner containers may be provided into which a plurality of sorbing liquids are respectively introduced for simultaneously detecting different analytes. Baffles may be provided in the outer container. A calibration technique is disclosed.

  4. System and method for detecting cells or components thereof

    DOEpatents

    Porter, Marc D [Ames, IA; Lipert, Robert J [Ames, IA; Doyle, Robert T [Ames, IA; Grubisha, Desiree S [Corona, CA; Rahman, Salma [Ames, IA

    2009-01-06

    A system and method for detecting a detectably labeled cell or component thereof in a sample comprising one or more cells or components thereof, at least one cell or component thereof of which is detectably labeled with at least two detectable labels. In one embodiment, the method comprises: (i) introducing the sample into one or more flow cells of a flow cytometer, (ii) irradiating the sample with one or more light sources that are absorbed by the at least two detectable labels, the absorption of which is to be detected, and (iii) detecting simultaneously the absorption of light by the at least two detectable labels on the detectably labeled cell or component thereof with an array of photomultiplier tubes, which are operably linked to two or more filters that selectively transmit detectable emissions from the at least two detectable labels.

  5. Development for equipment of the milk macromolecules content detection

    NASA Astrophysics Data System (ADS)

    Ding, Guochao; Li, Weimin; Shang, Tingyi; Xi, Yang; Gao, Yunli; Zhou, Zhen

    Developed an experimental device for rapid and accurate detection of milk macromolecular content. This device developed based on laser scattered through principle, the principle use of the ingredients of the scattered light and transmitted light ratio characterization of macromolecules. Peristaltic pump to achieve automatic input and output of the milk samples, designing weak signal detection amplifier circuit for detecting the ratio with ICL7650. Real-time operating system μC / OS-II is the core design of the software part of the whole system. The experimental data prove that the device can achieve a fast real-time measurement of milk macromolecules.

  6. A Deeper Look at the Fundamentals of Heterodyne Detection Requirements

    NASA Technical Reports Server (NTRS)

    Roychoudhuri, Chandrasekhar; Prasad, Narasimha S.

    2007-01-01

    We generally accept the experimentally observed criteria for heterodyne detections that the two waves that are mixed must (i) be collinear, (ii) have matched wave fronts and (iii) cannot be orthogonally polarized. We have not found in the literature adequate physical explanations for these requirements. The purpose of this paper is to find deeper physical understanding of the coherent heterodyne detection processes that could lead to better coherent laser radar system designs1. We find that there are a number of unresolved paradoxes in classical and quantum optics regarding the definitions and understanding of the "interference" and "coherence" properties of light, which are attributed as essentially due to inherent properties of the EM waves. A deeper exploration indicates that it is the various quantum mechanical properties of the detecting material dipoles that make light detectable (visible, or measurable) to us. Accordingly, all the properties that we generally attribute to only light, are in reality manifestations of collective properties of dipole-light interactions. "Interference" and "coherence" can be better understood in terms of this mutual interaction, followed by energy absorption by the dipoles from EM wave fields, manifesting in some measurable transformation of the detecting dipoles. Light beams do not interfere by themselves. The superposition effects due to light beams become manifest through the response characteristics of the detecting dipoles. In this paper, we will show some preliminary expe rimental results that clearly demonstrate that the heterodyning wave fronts have quantitative degradation in signal generation as the angle between them deviates from perfect collinearity. Subsequently, we will propose a hypothesis for this behavior. We will present experimental data establishing that the so called incoherent light can be detected through heterodyne mixing as long as the pulse length contained in the "incoherent" light is longer than the response time of the detector. We will also present a correspondingly better interpretation of two distinguishable coherence properties, temporal coherence and spectral coherence. Our investigation provides a deeper insight into how to rela x various system requirements for heterodyne detection and accordingly develop systems that are simpler, more reliable and lower in cost. Also, we believe that engineering of detector architecture by appropriately modifying dipole behavior using emerging nanotechnology to optimize heterodyne efficiency will be advantageous.

  7. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Wenfang; Du, Jinjin; Wen, Ruijuan

    We have investigated the transmission spectra of a Fabry-Perot interferometer (FPI) with squeezed vacuum state injection and non-Gaussian detection, including photon number resolving detection and parity detection. In order to show the suitability of the system, parallel studies were made of the performance of two other light sources: coherent state of light and Fock state of light either with classical mean intensity detection or with non-Gaussian detection. This shows that by using the squeezed vacuum state and non-Gaussian detection simultaneously, the resolution of the FPI can go far beyond the cavity standard bandwidth limit based on the current techniques. Themore » sensitivity of the scheme has also been explored and it shows that the minimum detectable sensitivity is better than that of the other schemes.« less

  8. First Light from Extrasolar Planets and Implications for Astrobiology

    NASA Technical Reports Server (NTRS)

    Richardson, L. Jeremy; Seager, Sara; Harrington, Joseph; Deming, Drake

    2005-01-01

    The first light from an extrasolar planet was recently detected. These results, obtained for two transiting extrasolar planets at different infrared wavelengths, open a new era in the field of extrasolar planet detection and characterization because for the first time we can now detect planets beyond the solar system directly. Using the Spitzer Space Telescope at 24 microns, we observed the modulation of combined light (star plus planet) from the HD 209458 system as the planet disappeared behind the star during secondary eclipse and later re-emerged, thereby isolating the light from the planet. We obtained a planet-to-star ratio of 0.26% at 24 microns, corresponding to a brightness temperature of 1130 + / - 150 K. We will describe this result in detail, explain what it can tell us about the atmosphere of HD 209458 b, and discuss implications for the field of astrobiology. These results represent a significant step on the path to detecting terrestrial planets around other stars and in understanding their atmospheres in terms of composition and temperature.

  9. Active polarization imaging system based on optical heterodyne balanced receiver

    NASA Astrophysics Data System (ADS)

    Xu, Qian; Sun, Jianfeng; Lu, Zhiyong; Zhou, Yu; Luan, Zhu; Hou, Peipei; Liu, liren

    2017-08-01

    Active polarization imaging technology has recently become the hot research field all over the world, which has great potential application value in the military and civil area. By introducing active light source, the Mueller matrix of the target can be calculated according to the incident light and the emitted or reflected light. Compared with conventional direct detection technology, optical heterodyne detection technology have higher receiving sensitivities, which can obtain the whole amplitude, frequency and phase information of the signal light. In this paper, an active polarization imaging system will be designed. Based on optical heterodyne balanced receiver, the system can acquire the horizontal and vertical polarization of reflected optical field simultaneously, which contain the polarization characteristic of the target. Besides, signal to noise ratio and imaging distance can be greatly improved.

  10. Research of the chemiluminescence detection apparatus for nutrients

    NASA Astrophysics Data System (ADS)

    Xu, Xiaoyi; Wang, Yu; Ni, Xuxiang; Yan, Huimin

    2016-10-01

    The multifunctional nutrition analyzer, which integrates four detection functions, can make fast, accurate, quantitative analysis for a variety of nutrients. In this article we focus on researching the luminescence detection system. Compared with other means, luminescence detection needs no excitation light, and the detection sensitivity is improved due to the reduction of the background light. The apparatus consists of an displacement platform, a microporous plate, a combination of an aspheric lens and a plano-convex lens, an optical fiber and a photon counter connected with a computer. A theoretical light intensity formula is established as a reference and a comparison of the experimental data. In the experiment we applies ATP detection reagent as the experimental reagent, whose magnitudes of concentration are from 10-6 mol/L to 10-12 mol/L. The sensitivity of the apparatus could reach a magnitude of concentration of 0.1nmol/L, and it is estimated to be further improved by at least two magnitudes in theory with the system and the reagent optimized.

  11. A time-domain fluorescence diffusion optical tomography system for breast tumor diagnosis

    NASA Astrophysics Data System (ADS)

    Zhang, Wei; Gao, Feng; Wu, LinHui; Ma, Wenjuan; Yang, Fang; Zhou, Zhongxing; Zhang, Limin; Zhao, Huijuan

    2011-02-01

    A prototype time-domain fluorescence diffusion optical tomography (FDOT) system using near-infrared light is presented. The system employs two pulsed light sources, 32 source fibers and 32 detection channels, working separately for acquiring the temporal distribution of the photon flux on the tissue surface. The light sources are provided by low power picosecond pulsed diode lasers at wavelengths of 780 nm and 830 nm, and a 1×32-fiber-optic-switch sequentially directs light sources to the object surface through 32 source fibers. The light signals re-emitted from the object are collected by 32 detection fibers connected to four 8×1 fiber-optic-switch and then routed to four time-resolved measuring channels, each of which consists of a collimator, a filter wheel, a photomultiplier tube (PMT) photon-counting head and a time-correlated single photon counting (TCSPC) channel. The performance and efficacy of the designed multi-channel PMT-TCSPC system are assessed by reconstructing the fluorescent yield and lifetime images of a solid phantom.

  12. Development of a rapid immunoassay system: Luminescent detection of antigen-associated antibody-luciferase in the presence of a dye that absorbs light from free antibody-luciferase.

    PubMed

    Mori, Akihiro; Ojima-Kato, Teruyo; Fuchi, Shingo; Kaiya, Shinichi; Kojima, Takaaki; Nakano, Hideo

    2017-12-01

    In this report, we developed a rapid immunoassay system, designated the bioluminescent interference gathering optical (BINGO) assay, which required no time-consuming washing steps for removal of unbound antibodies. This system employed a luciferase (Luc)-conjugated antibody (LucAb) and a dye that absorbed light from the LucAb. The antigen-associated LucAb was localized by transfer of an antigen to the detector-side of a chamber where a detector photomultiplier tube (PMT) was installed. In contrast, the free LucAb was distributed throughout the solution, and the light emitted by the free LucAb was absorbed by the dye. Therefore, only light from LucAb associated with antigen could be detected by the PMT. The new system could be used to rapidly detect the amount of antigen-antibody-Luc complex by collecting steps, such as centrifugation or magnetic collection of antibody-coated magnetic beads. Proof-of-principle experiments were performed using a model system with streptavidin beads and biotinylated Luc. The feasibility of the system was demonstrated using magnetic beads coated with anti-Escherichia coli O157 antibody, enabling detection of 4 × 10 3  cells in only 15 min. Thus, this system may have applications in a variety of biomedical fields. Copyright © 2017 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  13. A versatile fiber-optic coupled system for sensitive optical spectroscopy in strong ambient light

    NASA Astrophysics Data System (ADS)

    Sinha, Sudarson Sekhar; Verma, Pramod Kumar; Makhal, Abhinandan; Pal, Samir Kumar

    2009-05-01

    In this work we describe design and use of a fiber-optic based optical system for the spectroscopic studies on the samples under the presence of strong ambient light. The system is tested to monitor absorption, emission, and picosecond-resolved fluorescence transients simultaneously with a time interval of 500 ms for several hours on a biologically important sample (vitamin B2) under strong UV light. An efficient stray-light rejection ratio of the setup is achieved by the confocal geometry of the excitation and detection channels. It is demonstrated using this setup that even low optical signal from a liquid sample under strong UV-exposure for the picosecond-resolved fluorescence transient measurement can reliably be detected by ultrasensitive microchannel plate photomultiplier tube solid state detector. The kinetics of photodeterioration of vitamin B2 measured using our setup is consistent with that reported in the literature. Our present studies also justify the usage of tungsten light than the fluorescent light for the healthy preservation of food with vitamin B2.

  14. Sky light polarization detection with linear polarizer triplet in light field camera inspired by insect vision.

    PubMed

    Zhang, Wenjing; Cao, Yu; Zhang, Xuanzhe; Liu, Zejin

    2015-10-20

    Stable information of a sky light polarization pattern can be used for navigation with various advantages such as better performance of anti-interference, no "error cumulative effect," and so on. But the existing method of sky light polarization measurement is weak in real-time performance or with a complex system. Inspired by the navigational capability of a Cataglyphis with its compound eyes, we introduce a new approach to acquire the all-sky image under different polarization directions with one camera and without a rotating polarizer, so as to detect the polarization pattern across the full sky in a single snapshot. Our system is based on a handheld light field camera with a wide-angle lens and a triplet linear polarizer placed over its aperture stop. Experimental results agree with the theoretical predictions. Not only real-time detection but simple and costless architecture demonstrates the superiority of the approach proposed in this paper.

  15. Distributed gas detection system and method

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Challener, William Albert; Palit, Sabarni; Karp, Jason Harris

    A distributed gas detection system includes one or more hollow core fibers disposed in different locations, one or more solid core fibers optically coupled with the one or more hollow core fibers and configured to receive light of one or more wavelengths from a light source, and an interrogator device configured to receive at least some of the light propagating through the one or more solid core fibers and the one or more hollow core fibers. The interrogator device is configured to identify a location of a presence of a gas-of-interest by examining absorption of at least one of themore » wavelengths of the light at least one of the hollow core fibers.« less

  16. Optical backscatter probe for sensing particulate in a combustion gas stream

    DOEpatents

    Parks, James E; Partridge, William P

    2013-05-28

    A system for sensing particulate in a combustion gas stream is disclosed. The system transmits light into a combustion gas stream, and thereafter detects a portion of the transmitted light as scattered light in an amount corresponding to the amount of particulates in the emissions. Purge gas may be supplied adjacent the light supply and the detector to reduce particles in the emissions from coating or otherwise compromising the transmission of light into the emissions and recovery of scattered light from the emissions.

  17. Structured Light-Based Hazard Detection For Planetary Surface Navigation

    NASA Technical Reports Server (NTRS)

    Nefian, Ara; Wong, Uland Y.; Dille, Michael; Bouyssounouse, Xavier; Edwards, Laurence; To, Vinh; Deans, Matthew; Fong, Terry

    2017-01-01

    This paper describes a structured light-based sensor for hazard avoidance in planetary environments. The system presented here can also be used in terrestrial applications constrained by reduced onboard power and computational complexity and low illumination conditions. The sensor is on a calibrated camera and laser dot projector system. The onboard hazard avoidance system determines the position of the projected dots in the image and through a triangulation process detects potential hazards. The paper presents the design parameters for this sensor and describes the image based solution for hazard avoidance. The system presented here was tested extensively in day and night conditions in Lunar analogue environments. The current system achieves over 97 detection rate with 1.7 false alarms over 2000 images.

  18. Ophthalmological OCT measuring arm design

    NASA Astrophysics Data System (ADS)

    Xu, Xiaonan; Gao, Jiansong; Guo, Jihua; Xue, Ping

    2002-06-01

    This paper presents a novel ophthamological optical coherence tomography detecting instrument that we design and introduces measuring arm emphatically. For the glaucoma is very common in the orient, this system can achieve both the eyeground detection and the canthus detection. And it combines the cranny lamp's conventional detection with optical coherence tomography. In order to gain the best resolution and the largest scanning range in the OCT detection, we find the optical system should obey these principles in the measuring arm design: (i) the parallel light from the collimator goes through the lens and focuses on the slot of the cranny lamp. The movement of the scanning point produced by the scanner is carrying on along the slot. (Ii) In the whole light route, the scanner images on the laser object lens of the OCT. The center light of the infrared goes through the center of the object lens all the time. Considering all the system, this design has a longitudinal resolution of 15micrometers , and a transverse resolution of 20micrometers at imaging velocity of 4 frames per second.

  19. Investigation of the sensitivity of a cross-polarized light visualization system to detect subclinical erythema and dryness in women with vulvovaginitis.

    PubMed

    Farage, Miranda A; Singh, Mukul; Ledger, William J

    2009-07-01

    An enhanced visualization technique using polarized light (Syris v600 enhanced visualization system; Syris Scientific LLC, Gray, ME) detects surface and subsurface ( approximately 1 mm depth) inflammation. We sought to compare the Syris v600 system with unaided visual inspection and colposcopy of the female genitalia. Erythema and dryness of the vulva, introitus, vagina, and cervix were visualized and scored by each method in patients with and without vulvitis. Subsurface visualization was more sensitive in detecting genital erythema and dryness at all sites whether or not symptoms were present. Subsurface inflammation of the introitus, vagina, and cervix only was detected uniquely in women with vulvar vestibulitis syndrome (VVS). A subset of women presenting with VVS exhibited subclinical inflammation of the vulva vestibule and vagina (designated VVS/lichen sclerosus subgroup). Enhanced visualization of the genital epithelial subsurface with cross-polarized light may assist in diagnosing subclinical inflammation in vulvar conditions heretofore characterized as sensory syndromes.

  20. Optical detection dental disease using polarized light

    DOEpatents

    Everett, Matthew J.; Colston, Jr., Billy W.; Sathyam, Ujwal S.; Da Silva, Luiz B.; Fried, Daniel

    2003-01-01

    A polarization sensitive optical imaging system is used to detect changes in polarization in dental tissues to aid the diagnosis of dental disease such as caries. The degree of depolarization is measured by illuminating the dental tissue with polarized light and measuring the polarization state of the backscattered light. The polarization state of this reflected light is analyzed using optical polarimetric imaging techniques. A hand-held fiber optic dental probe is used in vivo to direct the incident beam to the dental tissue and collect the reflected light. To provide depth-resolved characterization of the dental tissue, the polarization diagnostics may be incorporated into optical coherence domain reflectometry and optical coherence tomography (OCDR/OCT) systems, which enables identification of subsurface depolarization sites associated with demineralization of enamel or bone.

  1. Gimbaled multispectral imaging system and method

    DOEpatents

    Brown, Kevin H.; Crollett, Seferino; Henson, Tammy D.; Napier, Matthew; Stromberg, Peter G.

    2016-01-26

    A gimbaled multispectral imaging system and method is described herein. In an general embodiment, the gimbaled multispectral imaging system has a cross support that defines a first gimbal axis and a second gimbal axis, wherein the cross support is rotatable about the first gimbal axis. The gimbaled multispectral imaging system comprises a telescope that fixed to an upper end of the cross support, such that rotation of the cross support about the first gimbal axis causes the tilt of the telescope to alter. The gimbaled multispectral imaging system includes optics that facilitate on-gimbal detection of visible light and off-gimbal detection of infrared light.

  2. Device and nondestructive method to determine subsurface micro-structure in dense materials

    DOEpatents

    Sun, Jiangang [Westmont, IL

    2006-05-09

    A method and a device to detect subsurface three-dimensional micro-structure in a sample by illuminating the sample with light of a given polarization and detecting light emanating from the sample that has a different direction of polarization by means of a confocal optical system.

  3. Light-controlled resistors provide quadrature signal rejection for high-gain servo systems

    NASA Technical Reports Server (NTRS)

    Mc Cauley, D. D.

    1967-01-01

    Servo amplifier feedback system, in which the phase sensitive detection, low pass filtering, and multiplication functions required for quadrature rejection, are preformed by light-controlled photoresistors, eliminates complex circuitry. System increases gain, improves signal-to-noise ratio, and eliminates the necessity for compensation.

  4. Caries Detection around Restorations Using ICDAS and Optical Devices.

    PubMed

    Diniz, Michele Baffi; Eckert, George Joseph; González-Cabezas, Carlos; Cordeiro, Rita de Cássia Loiola; Ferreira-Zandona, Andrea Gonçalves

    2016-01-01

    Secondary caries is the major reason for replacement of restorations in operative dentistry. New detection methods and technology have the potential to improve the accuracy for diagnosis of secondary carious lesions. This in vitro study evaluated the performance of the ICDAS (International Caries Detection and Assessment System) visual criteria and optical devices for detecting secondary caries around amalgam and composite resin restorations in permanent teeth. A total of 180 extracted teeth with Class I amalgam (N = 90) and resin composite (N = 90) restorations were selected. Two examiners analyzed the teeth twice using the visual criteria (ICDAS), laser fluorescence (LF), light-emitting diode device (MID), quantitative light-induced fluorescence system (QLF), and a prototype system based on the Fluorescence Enamel Imaging technique (Professional Caries Detection System, PCDS). The gold standard was determined by means of confocal laser scanning microscopy. High-reproducibility values were shown for all methods, except for MID in the amalgam group. For both groups the QLF and PCDS were the most sensitive methods, whereas the other methods presented better specificity (p < 0.05). All methods, except the MID device appeared to be potential methods for detecting secondary caries only around resin composite restorations, whereas around amalgam restorations all methods seemed to be questionable. Using Internal Caries Detection and Assessment System (ICDAS), an LF device, quantitative light-induced fluorescence and a novel method based on Fluorescence Enamel Imaging technique may be effective for evaluating secondary caries around composite resin restorations. © 2016 Wiley Periodicals, Inc.

  5. Liquid argon scintillation detection utilizing wavelength-shifting plates and light guides

    NASA Astrophysics Data System (ADS)

    Howard, B.

    2018-02-01

    In DUNE, the event timing provided by the detection of the relatively prompt scintillation photons will improve spatial resolution in the drift direction of the time-projection chamber (TPC) and is especially useful for non-beam physics topics such as supernova neutrinos and nucleon decay. The baseline design for the first 10kt single phase TPC fits the photon detector system in the natural gap between the wire planes of adjacent TPC volumes. A prototype photon detector design utilizes wavelength-shifter coated plates to convert the vacuum ultraviolet scintillation light to the optical and commercially-produced wavelength-shifting light guides to trap some of this light and transport it to an array of silicon photomultipliers at the end. This system and the testing performed to characterize the system and determine the efficiency are discussed.

  6. Investigation of light scattering as a technique for detecting discrete soot particles in a luminous flame

    NASA Technical Reports Server (NTRS)

    1978-01-01

    The practicability of using a classical light-scattering technique, involving comparison of angular scattering intensity patterns with theoretically determined Mie and Rayleight patterns, to detect discrete soot particles (diameter less than 50 nm) in premixed propane/air and propane/oxygen-helium flames is considered. The experimental apparatus employed in this investigation included a laser light source, a flat-flame burner, specially coated optics, a cooled photomultiplier detector, and a lock-in voltmeter readout. Although large, agglomerated soot particles were detected and sized, it was not possible to detect small, discrete particles. The limiting factor appears to be background scattering by the system's optics.

  7. Linear array optical edge sensor

    NASA Technical Reports Server (NTRS)

    Bejczy, Antal K. (Inventor); Primus, Howard C. (Inventor)

    1987-01-01

    A series of independent parallel pairs of light emitting and detecting diodes for a linear pixel array, which is laterally positioned over an edge-like discontinuity in a workpiece to be scanned, is disclosed. These independent pairs of light emitters and detectors sense along intersecting pairs of separate optical axes. A discontinuity, such as an edge in the sensed workpiece, reflects a detectable difference in the amount of light from that discontinuity in comparison to the amount of light that is reflected on either side of the discontinuity. A sequentially sychronized clamping and sampling circuit detects that difference as an electrical signal which is recovered by circuitry that exhibits an improved signal-to-noise capability for the system.

  8. Pediatric vision screening using binocular retinal birefringencr scanning

    NASA Astrophysics Data System (ADS)

    Nassif, Deborah S.; Gramatikov, Boris; Guyton, David L.; Hunter, David G.

    2003-07-01

    Amblyopia, a leading cause of vision loss in childhood, is responsive to treatment if detected early in life. Risk factors for amblyopia, such as refractive error and strabismus, may be difficult to identify clinically in young children. Our laboratory has developed retinal birefringence scanning (RBS), in which a small spot of polarized light is scanned in a circle on the retina, and the returning light is measured for changes in polarization caused by the pattern of birefringent fibers that comprise the fovea. Binocular RBS (BRBS) detects the fixation of both eyes simultaneously and thus screens for strabismus, one of the risk factors of amblyopia. We have also developed a technique to automatically detect when the eye is in focus without measuring refractive error. This focus detection system utilizes a bull's eye photodetector optically conjugate to a point fixation source. Reflected light is focused back to the point source by the optical system of the eye, and if the subject focuses on the fixation source, the returning light will be focused on the detector. We have constructed a hand-held prototype combining BRBS and focus detection measurements in one quick (< 0.5 second) and accurate (theoretically detecting +/-1 of misalignment) measurement. This approach has the potential to reliably identify children at risk for amblyopia.

  9. Findings from Matching VIIRS Boat Detection and VMS Data

    NASA Astrophysics Data System (ADS)

    Hsu, F. C.; Elvidge, C.; Zhizhin, M. N.; Baugh, K.; Ghosh, T.

    2017-12-01

    With the superior nigthtime sensitivity and spatial resolution provided by VIIRS Day Night Band, we had developed algorithm known as VIIRS Boat Detection (VBD) to detect fishing vessels active at night using light to attract schools of fish. While VBD is effective in finding bright boats, little is known on the nature of boats that emits such bright lights. To complement the missing attribute of VBD detections, the authors find aid from Vessel Monitoring System (VMS) data. VMS is widely used in monitoring fishing vessels logging their coordinate nominally every hour, along with vessel specifications such as tonnage, size, and gear type. This study matches VMS records with VBD detections, broadening the understanding of the lighting streategy used by fisherman, and provide valuable assumption on possible vessel types for VBD detections.

  10. Light guide technology: using light to enhance safety

    NASA Astrophysics Data System (ADS)

    Lerner, William S.

    2009-05-01

    When used to detect extreme temperatures in harsh environments, warning devices have been placed at a distance from the "danger zone" for several reasons. The inability to mix electricity with flammable, caustic, liquid or volatile substances, the limited heat tolerances exhibited by most light sources, and the susceptibility of light sources to damage from vibration, have made the placement of a warning light directly within these harsh environments impossible. This paper describes a system that utilizes a beam of light to provide just such a warning. This system can be used with hard-wired or wireless sensors, side-light illumination, image projection and image transfer. The entire system may be self-contained and portable.

  11. Backscatter absorption gas imaging system

    DOEpatents

    McRae, Jr., Thomas G.

    1985-01-01

    A video imaging system for detecting hazardous gas leaks. Visual displays of invisible gas clouds are produced by radiation augmentation of the field of view of an imaging device by radiation corresponding to an absorption line of the gas to be detected. The field of view of an imager is irradiated by a laser. The imager receives both backscattered laser light and background radiation. When a detectable gas is present, the backscattered laser light is highly attenuated, producing a region of contrast or shadow on the image. A flying spot imaging system is utilized to synchronously irradiate and scan the area to lower laser power requirements. The imager signal is processed to produce a video display.

  12. Backscatter absorption gas imaging system

    DOEpatents

    McRae, T.G. Jr.

    A video imaging system for detecting hazardous gas leaks. Visual displays of invisible gas clouds are produced by radiation augmentation of the field of view of an imaging device by radiation corresponding to an absorption line of the gas to be detected. The field of view of an imager is irradiated by a laser. The imager receives both backscattered laser light and background radiation. When a detectable gas is present, the backscattered laser light is highly attenuated, producing a region of contrast or shadow on the image. A flying spot imaging system is utilized to synchronously irradiate and scan the area to lower laser power requirements. The imager signal is processed to produce a video display.

  13. Light collection device for flame emission detectors

    DOEpatents

    Woodruff, Stephen D.; Logan, Ronald G.; Pineault, Richard L.

    1990-01-01

    A light collection device for use in a flame emission detection system such as an on-line, real-time alkali concentration process stream monitor is disclosed which comprises a sphere coated on its interior with a highly diffuse reflective paint which is positioned over a flame emission source, and one or more fiber optic cables which transfer the light generated at the interior of the sphere to a detecting device. The diffuse scattering of the light emitted by the flame uniformly distributes the light in the sphere, and the collection efficiency of the device is greater than that obtainable in the prior art. The device of the present invention thus provides enhanced sensitivity and reduces the noise associated with flame emission detectors, and can achieve substantial improvements in alkali detection levels.

  14. An Automated Flying-Insect Detection System

    NASA Technical Reports Server (NTRS)

    Vann, Timi; Andrews, Jane C.; Howell, Dane; Ryan, Robert

    2007-01-01

    An automated flying-insect detection system (AFIDS) was developed as a proof-of-concept instrument for real-time detection and identification of flying insects. This type of system has use in public health and homeland-security decision support, agriculture and military pest management, and/or entomological research. Insects are first lured into the AFIDS integrated sphere by insect attractants. Once inside the sphere, the insect s wing beats cause alterations in light intensity that is detected by a photoelectric sensor. Following detection, the insects are encouraged (with the use of a small fan) to move out of the sphere and into a designated insect trap where they are held for taxonomic identification or serological testing. The acquired electronic wing-beat signatures are preprocessed (Fourier transformed) in real time to display a periodic signal. These signals are sent to the end user where they are graphically. All AFIDS data are preprocessed in the field with the use of a laptop computer equipped with LabVIEW. The AFIDS software can be programmed to run continuously or at specific time intervals when insects are prevalent. A special DC-restored transimpedance amplifier reduces the contributions of low-frequency background light signals, and affords approximately two orders of magnitude greater AC gain than conventional amplifiers. This greatly increases the signal-to-noise ratio and enables the detection of small changes in light intensity. The AFIDS light source consists of high-intensity Al-GaInP light-emitting diodes (LEDs). The AFIDS circuitry minimizes brightness fluctuations in the LEDs and when integrated with an integrating sphere, creates a diffuse uniform light field. The insect wing beats isotropically scatter the diffuse light in the sphere and create wing-beat signatures that are detected by the sensor. This configuration minimizes variations in signal associated with insect flight orientation. Preliminary data indicate that AFIDS has sufficient sensitivity and frequency measuring capability to differentiate between male and female mosquitoes (Figure 1, bottom panel) and fruit flies (data not shown). Similar studies show that AFIDS can be utilized to detect discrete differences between two mosquito species, Aedes aegypti and Aedes albopictus. When fully deployable, a wireless network of AFIDS monitors could be used in combination with other remotely sensed data and visually displayed in a geographic information system (GIS) to provide real-time surveillance (see Figure 2). More accurate and sensitive insect population forecasts and effective rapid response and mitigation of insect issues would then be possible.

  15. Noise suppressing capillary separation system

    DOEpatents

    Yeung, Edward S.; Xue, Yongjun

    1996-07-30

    A noise-suppressing capillary separation system for detecting the real-time presence or concentration of an analyte in a sample is provided. The system contains a capillary separation means through which the analyte is moved, a coherent light source that generates a beam which is split into a reference beam and a sample beam that irradiate the capillary, and a detector for detecting the reference beam and the sample beam light that transmits through the capillary. The laser beam is of a wavelength effective to be absorbed by a chromophore in the capillary. The system includes a noise suppressing system to improve performance and accuracy without signal averaging or multiple scans.

  16. Noise suppressing capillary separation system

    DOEpatents

    Yeung, E.S.; Xue, Y.

    1996-07-30

    A noise-suppressing capillary separation system for detecting the real-time presence or concentration of an analyte in a sample is provided. The system contains a capillary separation means through which the analyte is moved, a coherent light source that generates a beam which is split into a reference beam and a sample beam that irradiate the capillary, and a detector for detecting the reference beam and the sample beam light that transmits through the capillary. The laser beam is of a wavelength effective to be absorbed by a chromophore in the capillary. The system includes a noise suppressing system to improve performance and accuracy without signal averaging or multiple scans. 13 figs.

  17. Optical-fiber-based laser-induced breakdown spectroscopy for detection of early caries

    NASA Astrophysics Data System (ADS)

    Sasazawa, Shuhei; Kakino, Satoko; Matsuura, Yuji

    2015-06-01

    A laser-induced breakdown spectroscopy (LIBS) system targeting for the in vivo analysis of tooth enamel is described. The system is planned to enable real-time analysis of teeth during laser dental treatment by utilizing a hollow optical fiber that transmits both Q-switched Nd:YAG laser light for LIBS and infrared Er:YAG laser light for tooth ablation. The sensitivity of caries detection was substantially improved by expanding the spectral region under analysis to ultraviolet (UV) light and by focusing on emission peaks of Zn in the UV region. Subsequently, early caries were distinguished from healthy teeth with accuracy rates above 80% in vitro.

  18. Efficacy of the ViziLite system in the identification of oral lesions.

    PubMed

    Oh, Esther S; Laskin, Daniel M

    2007-03-01

    Early detection of oral cancer is crucial in improving survival rate. To improve early detection, the use of a dilute acetic acid rinse and observation under a chemiluminescent light (ViziLite; Zila Pharmaceuticals, Phoenix, AZ) has been recommended. However, to date, the contributions of the individual components of the system have not been studied. The present study was done to investigate the efficacy of the individual components of the ViziLite system in providing improved visualization of early oral mucosal lesions. A total of 100 patients, 39 males and 61 females, age 18 to 93 years (mean age, 44 years), who presented to the Virginia Commonwealth University School of Dentistry for dental screening were examined. There were 58 Caucasians, 29 African-Americans, 5 Hispanics, 6 Asians, and 2 of mixed ethnicity. Thirty-five patients smoked, 53 used alcohol, and 25 both smoked and drank. After written consent, the oral cavity was examined under incandescent light for soft tissue abnormalities. After 1-minute rinse with 1% acetic acid, the mouth was re-examined for additional mucosal abnormalities. Then, the mouth was examined once again using the ViziLite system's chemiluminescent light. Any lesions detected by these 3 examinations that were clinically undiagnosable were brush biopsied (Oral CDx) for determination of cellular representation. In the original examination of the 100 patients, 57 clinically diagnosable benign lesions (eg, linea alba, leukoedema) and 29 clinically undiagnosable lesions were detected. After the rinse, 6 additional diagnosable lesions (linea alba) and 3 undiagnosable lesions were found. No additional lesions were detected with the chemiluminescent light. Of the 32 undiagnosable lesions that were brush biopsied, 2 were positive for atypical cellular characterization and warranted further investigation with a scalpel biopsy. Neither of these lesions was found to be premalignant or malignant. Although the acid rinse accentuated some lesions, the overall detection rate was not significantly improved. The chemiluminescent light produced reflections that made visualization more difficult and thus was not beneficial.

  19. A portable fluorescent sensing system using multiple LEDs

    NASA Astrophysics Data System (ADS)

    Shin, Young-Ho; Barnett, Jonathan Z.; Gutierrez-Wing, M. Teresa; Rusch, Kelly A.; Choi, Jin-Woo

    2017-02-01

    This paper presents a portable fluorescent sensing system that utilizes different light emitting diode (LED) excitation lights for multiple target detection. In order to identify different analytes, three different wavelengths (385 nm, 448 nm, and 590 nm) of excitation light emitting diodes were used to selectively stimulate the target analytes. A highly sensitive silicon photomultiplier (SiPM) was used to detect corresponding fluorescent signals from each analyte. Based on the unique fluorescent response of each analyte, it is possible to simultaneously differentiate one analyte from the other in a mixture of target analytes. A portable system was designed and fabricated consisting of a display module, battery, data storage card, and sample loading tray into a compact 3D-printed jig. The portable sensor system was demonstrated for quantification and differentiation of microalgae (Chlorella vulgaris) and cyanobacteria (Spirulina) by measuring fluorescent responses of chlorophyll a in microalgae and phycocyanin in cyanobacteria. Obtained results suggest that the developed portable sensor system could be used as a generic fluorescence sensor platform for on-site detection of multiple analytes of interest.

  20. Method, apparatus and system for low-energy beta particle detection

    DOEpatents

    Akers, Douglas W.; Drigert, Mark W.

    2012-09-25

    An apparatus, method, and system relating to radiation detection of low-energy beta particles are disclosed. An embodiment includes a radiation detector with a first scintillator and a second scintillator operably coupled to each other. The first scintillator and the second scintillator are each structured to generate a light pulse responsive to interaction with beta particles. The first scintillator is structured to experience full energy deposition of low-energy beta particles, and permit a higher-energy beta particle to pass therethrough and interact with the second scintillator. The radiation detector further includes a light-to-electrical converter operably coupled to the second scintillator and configured to convert light pulses generated by the first scintillator and the second scintillator into electrical signals. The first scintillator and the second scintillator have at least one mutually different characteristic to enable an electronic system to determine whether a given light pulse is generated in the first scintillator or the second scintillator.

  1. Addition of Adapted Optics towards obtaining a quantitative detection of diabetic retinopathy

    NASA Astrophysics Data System (ADS)

    Yust, Brian; Obregon, Isidro; Tsin, Andrew; Sardar, Dhiraj

    2009-04-01

    An adaptive optics system was assembled for correcting the aberrated wavefront of light reflected from the retina. The adaptive optics setup includes a superluminous diode light source, Hartmann-Shack wavefront sensor, deformable mirror, and imaging CCD camera. Aberrations found in the reflected wavefront are caused by changes in the index of refraction along the light path as the beam travels through the cornea, lens, and vitreous humour. The Hartmann-Shack sensor allows for detection of aberrations in the wavefront, which may then be corrected with the deformable mirror. It has been shown that there is a change in the polarization of light reflected from neovascularizations in the retina due to certain diseases, such as diabetic retinopathy. The adaptive optics system was assembled towards the goal of obtaining a quantitative measure of onset and progression of this ailment, as one does not currently exist. The study was done to show that the addition of adaptive optics results in a more accurate detection of neovascularization in the retina by measuring the expected changes in polarization of the corrected wavefront of reflected light.

  2. Detection of early caries by laser-induced breakdown spectroscopy

    NASA Astrophysics Data System (ADS)

    Sasazawa, Shuhei; Kakino, Satoko; Matsuura, Yuji

    2015-07-01

    To improve sensitivity of dental caries detection by laser-induced breakdown spectroscopy (LIBS) analysis, it is proposed to utilize emission peaks in the ultraviolet. We newly focused on zinc whose emission peaks exist in ultraviolet because zinc exists at high concentration in the outer layer of enamel. It was shown that by using ratios between heights of an emission peak of Zn and that of Ca, the detection sensitivity and stability are largely improved. It was also shown that early caries are differentiated from healthy part by properly setting a threshold in the detected ratios. The proposed caries detection system can be applied to dental laser systems such as ones based on Er:YAG-lasers. When ablating early caries part by laser light, the system notices the dentist that the ablation of caries part is finished. We also show the intensity of emission peaks of zinc decreased with ablation with Er:YAG laser light.

  3. Hierarchical scheme for detecting the rotating MIMO transmission of the in-door RGB-LED visible light wireless communications using mobile-phone camera

    NASA Astrophysics Data System (ADS)

    Chen, Shih-Hao; Chow, Chi-Wai

    2015-01-01

    Multiple-input and multiple-output (MIMO) scheme can extend the transmission capacity for the light-emitting-diode (LED) based visible light communication (VLC) systems. The MIMO VLC system that uses the mobile-phone camera as the optical receiver (Rx) to receive MIMO signal from the n×n Red-Green-Blue (RGB) LED array is desirable. The key step of decoding this signal is to detect the signal direction. If the LED transmitter (Tx) is rotated, the Rx may not realize the rotation and transmission error can occur. In this work, we propose and demonstrate a novel hierarchical transmission scheme which can reduce the computation complexity of rotation detection in LED array VLC system. We use the n×n RGB LED array as the MIMO Tx. In our study, a novel two dimensional Hadamard coding scheme is proposed. Using the different LED color layers to indicate the rotation, a low complexity rotation detection method can be used for improving the quality of received signal. The detection correction rate is above 95% in the indoor usage distance. Experimental results confirm the feasibility of the proposed scheme.

  4. Instrument for all-fiber structure measurement of ultra-low turbidity by using single photon detection technique

    NASA Astrophysics Data System (ADS)

    Qin, Feihu; Hu, Juntao; Wang, Huanqin; Gui, Huaqiao; Liu, Jianguo; Lü, Liang; Kong, Deyi; Zhang, Jian; Han, Xia; Wang, Tianli

    2017-10-01

    An all-fiber structure detection system based on single photon detection technique(SPDT) has been developed to measure the ultra-low turbidity ofliquids. To assure the measurement accuracy,the total intensity of transmission light has been detected and quantified as number of photons by avalanche photodiode (APD) which has the advantage of high sensitivity.A fresh all-fiber structure optical fiber probe based on SPDT is applied in the system to reduce the volume and fluctuation of traditional transmission-light measurement system,in which the all-fiber structure probe is used to delivery and collection of transmission light.On the basis of Beer-Lambert (B-L) transmission law,a test system has been established and carried out a series of experiments.By combining B-Llaw with the principle of SPDT,a novel model for detecting turbidity has been proposed to explain the experimental results.The results have shown a well exponential relationship over the range of 0.01-1NTU (Nephelometric Turbidity Units).It also has showna good linear relationship with a resolution as high as 0.01NTUin the range of 0.01-0.09 NTU.When it is 1 secondofthe sampling time,the mean error of measurement result can be controlled within 5% of full scale.In addition,the new detection structure proposed in this paper, which makes the system more compact and more suitable in the small special space.

  5. QUALITY ASSESSMENT OF CONFOCAL MICROSCOPY SLIDE-BASED SYSTEMS: INSTABLITY

    EPA Science Inventory

    Background: All slide-based fluorescence cytometry detections systems basically include an excitation light source, intermediate optics, and a detection device (CCD or PMT). Occasionally, this equipment becomes unstable, generating unreliable and inferior data. Methods: A num...

  6. Forgery Detection and Value Identification of Euro Banknotes

    PubMed Central

    Bruna, Arcangelo; Farinella, Giovanni Maria; Guarnera, Giuseppe Claudio; Battiato, Sebastiano

    2013-01-01

    This paper describes both hardware and software components to detect counterfeits of Euro banknotes. The proposed system is also able to recognize the banknote values. Differently than other state-of-the-art methods, the proposed approach makes use of banknote images acquired with a near infrared camera to perform recognition and authentication. This allows one to build a system that can effectively deal with real forgeries, which are usually not detectable with visible light. The hardware does not use any mechanical parts, so the overall system is low-cost. The proposed solution is reliable for ambient light and banknote positioning. Users should simply lean the banknote to be analyzed on a flat glass, and the system detects forgery, as well as recognizes the banknote value. The effectiveness of the proposed solution has been properly tested on a dataset composed by genuine and fake Euro banknotes provided by Italy's central bank. PMID:23429514

  7. The research and development of the non-contact detection of the tubing internal thread with a line structured light

    NASA Astrophysics Data System (ADS)

    Hu, Yuanyuan; Xu, Yingying; Hao, Qun; Hu, Yao

    2013-12-01

    The tubing internal thread plays an irreplaceable role in the petroleum equipment. The unqualified tubing can directly lead to leakage, slippage and bring huge losses for oil industry. For the purpose of improving efficiency and precision of tubing internal thread detection, we develop a new non-contact tubing internal thread measurement system based on the laser triangulation principle. Firstly, considering that the tubing thread had a small diameter and relatively smooth surface, we built a set of optical system with a line structured light to irradiate the internal thread surface and obtain an image which contains the internal thread profile information through photoelectric sensor. Secondly, image processing techniques were used to do the edge detection of the internal thread from the obtained image. One key method was the sub-pixel technique which greatly improved the detection accuracy under the same hardware conditions. Finally, we restored the real internal thread contour information on the basis of laser triangulation method and calculated tubing thread parameters such as the pitch, taper and tooth type angle. In this system, the profile of several thread teeth can be obtained at the same time. Compared with other existing scanning methods using point light and stepper motor, this system greatly improves the detection efficiency. Experiment results indicate that this system can achieve the high precision and non-contact measurement of the tubing internal thread.

  8. Design of Weft Detection System in The Stenter Machine

    NASA Astrophysics Data System (ADS)

    Gu, Minming; Xu, Xianju; Dai, Wenzhan

    2017-12-01

    In order to build an effective automatic weft-straightening system, it is important for the sensing device to detect most the possible fabric styles, designs, colours and structures, an optical sensing system that detects the angular orientation of weft threads in a moving web of a textile has been built. It contains an adjustable light source, two lens systems and photodiode sensor array. The sensor array includes 13 radial pattern of photosensitive areas that each generate an electrical signal proportional to the total intensity of the light incident on the area. The moving shadow of a weft thread passing over the area will modulate the output signal. A signal processed circuit was built to do the I/V conversion, amplifying, hardware filtering. An embed micro control system then deals with the information of these signals, calculates the angle of the weft drew. Finally, the experiments were done, the results showed that the weft detection system can deal with the fabric weft skew up to 30° and has achieved good results in the application.

  9. Efficient coding and detection of ultra-long IDs for visible light positioning systems.

    PubMed

    Zhang, Hualong; Yang, Chuanchuan

    2018-05-14

    Visible light positioning (VLP) is a promising technique to complement Global Navigation Satellite System (GNSS) such as Global positioning system (GPS) and BeiDou Navigation Satellite System (BDS) which features the advantage of low-cost and high accuracy. The situation becomes even more crucial for indoor environments, where satellite signals are weak or even unavailable. For large-scale application of VLP, there would be a considerable number of Light emitting diode (LED) IDs, which bring forward the demand of long LED ID detection. In particular, to provision indoor localization globally, a convenient way is to program a unique ID into each LED during manufacture. This poses a big challenge for image sensors, such as the CMOS camera in everybody's hands since the long ID covers the span of multiple frames. In this paper, we investigate the detection of ultra-long ID using rolling shutter cameras. By analyzing the pattern of data loss in each frame, we proposed a novel coding technique to improve the efficiency of LED ID detection. We studied the performance of Reed-Solomon (RS) code in this system and designed a new coding method which considered the trade-off between performance and decoding complexity. Coding technique decreases the number of frames needed in data processing, significantly reduces the detection time, and improves the accuracy of detection. Numerical and experimental results show that the detected LED ID can be much longer with the coding technique. Besides, our proposed coding method is proved to achieve a performance close to that of RS code while the decoding complexity is much lower.

  10. Novel system for pulse radiolysis with multi-angle light scattering detection (PR-MALLS) - concept, construction and first tests

    NASA Astrophysics Data System (ADS)

    Kadlubowski, S.; Sawicki, P.; Sowinski, S.; Rokita, B.; Bures, K. D.; Rosiak, J. M.; Ulanski, P.

    2018-01-01

    Time-resolved pulse radiolysis, utilizing short pulses of high-energy electrons from accelerators, is an effective method for rapidly generating free radicals and other transient species in solution. Combined with fast time-resolved spectroscopic detection (typically in the ultraviolet/visible/near-infrared), it is invaluable for monitoring the reactivity of species subjected to radiolysis on timescales ranging from picoseconds to seconds. When used for polymer solutions, pulse radiolysis can be coupled with light-scattering detection, creating a powerful tool for kinetic and mechanistic analysis of processes like degradation or cross-linking of macromolecules. Changes in the light scattering intensity (LSI) of polymer solutions are indicative of alterations in the molecular weight and/or in the radius of gyration, i.e., the dimensions and shape of the macromolecules. In addition to other detection methods, LSI technique provides a convenient tool to study radiation-induced alterations in macromolecules as a function of time after the pulse. Pulse radiolysis systems employing this detection mode have been so far constructed to follow light scattered at a single angle (typically the right angle) to the incident light beam. Here we present an advanced pulse radiolysis & multi-angle light-scattering-intensity system (PR-MALLS) that has been built at IARC and is currently in the phase of optimization and testing. Idea of its design and operation is described and preliminary results for radiation-induced degradation of pullulan as well as polymerization and crosslinking of poly(ethylene glycol) diacrylate are presented. Implementation of the proposed system provides a novel research tool, which is expected to contribute to the expansion of knowledge on free-radical reactions in monomer- and polymer solutions, by delivering precise kinetic data on changes in molecular weight and size, and thus allowing to formulate or verify reaction mechanisms. The proposed method is universal and can be applied for studying both natural and synthetic polymers. The developed system can be also valuable in studies of the border of biology and medicine, especially on radical reactions of biopolymers and their conformational transitions. Furthermore, capability to follow fast changes in mass and dimensions of nanobjects may be of significant importance for nanoscience and nanotechnology.

  11. Photon-Number-Resolving Transition-Edge Sensors for the Metrology of Quantum Light Sources

    NASA Astrophysics Data System (ADS)

    Schmidt, M.; von Helversen, M.; López, M.; Gericke, F.; Schlottmann, E.; Heindel, T.; Kück, S.; Reitzenstein, S.; Beyer, J.

    2018-05-01

    Low-temperature photon-number-resolving detectors allow for direct access to the photon number distribution of quantum light sources and can thus be exploited to explore the photon statistics, e.g., solid-state-based non-classical light sources. In this work, we report on the setup and calibration of a detection system based on fiber-coupled tungsten transition-edge sensors (W-TESs). Our stand-alone system comprises two W-TESs, read out by two 2-stage-SQUID current sensors, operated in a compact detector unit that is integrated in an adiabatic demagnetization refrigerator. Fast low-noise analog amplifiers and digitizers are used for signal acquisition. The detection efficiency of the single-mode fiber-coupled detector system in the spectral region of interest (850-950 nm) is determined to be larger than 87 %. The presented detector system opens up new routes in the characterization of quantum light sources for quantum information, quantum-enhanced sensing and quantum metrology.

  12. Quantum hacking on a practical continuous-variable quantum cryptosystem by inserting an external light

    NASA Astrophysics Data System (ADS)

    Qin, Hao; Kumar, Rupesh; Alleaume, Romain

    2015-10-01

    We report here a new side channel attack on a practical continuous-variable (CV) quantum key distribution (QKD) system. Inspired by blinding attack in discrete-variable QKD, we formalize an attack strategy by inserting an external light into a CV QKD system implemented Gaussian-modulated coherent state protocol and show that our attack can compromise its practical security. In this attack, we concern imperfections of a balanced homodyne detector used in CV QKD. According to our analysis, if one inserts an external light into Bob's signal port, due to the imperfect subtraction from the homodyne detector, the leakage of the external light contributes a displacement on the homodyne signal which causes detector electronics saturation. In consequence, Bob's quadrature measurement is not linear with the quadrature sent by Alice. By considering such vulnerability, a potential Eve can launch a full intercept-resend attack meanwhile she inserts an external light into Bob's signal port. By selecting proper properties of the external light, Eve actively controls the induced displacement value from the inserted light which results saturation of homodyne detection. In consequence, Eve can bias the excess noise due to the intercept-resend attack and the external light, such that Alice and Bob believe their excess noise estimation is below the null key threshold and they can still share a secret key. Our attack shows that the detector loopholes also exist in CV QKD, and it seems influence all the CV QKD systems using homodyne detection, since all the practical detectors have finite detection range.

  13. System Would Predictively Preempt Traffic Lights for Emergency Vehicles

    NASA Technical Reports Server (NTRS)

    Bachelder, Aaron; Foster, Conrad

    2004-01-01

    Two electronic communication-and-control systems have been proposed as means of modifying the switching of traffic lights to give priority to emergency vehicles. Both systems would utilize the inductive loops already installed in the streets of many municipalities to detect vehicles for timing the switching of traffic lights. The proposed systems could be used alone or to augment other automated emergency traffic-light preemption systems that are already present in some municipalities, including systems that recognize flashing lights or siren sounds or that utilize information on the positions of emergency vehicles derived from the Global Positioning System (GPS). Systems that detect flashing lights and siren sounds are limited in range, cannot "see" or "hear" well around corners, and are highly vulnerable to noise. GPS-based systems are effective in rural areas and small cities, but are often ineffective in large cities because of frequent occultation of GPS satellite signals by large structures. In contrast, the proposed traffic-loop forward prediction system would be relatively invulnerable to noise, would not be subject to significant range limitations, and would function well in large cities -- even in such places as underneath bridges and in tunnels, where GPS-based systems do not work. One proposed system has been characterized as "car-active" because each participating emergency vehicle would be equipped with a computer and a radio transceiver that would communicate with stationary transceivers at the traffic loops. The other proposed system has been characterized as "car-passive" because a passive radio transponder would be installed on the underside of a participating vehicle.

  14. Extended depth of field imaging for high speed object analysis

    NASA Technical Reports Server (NTRS)

    Frost, Keith (Inventor); Ortyn, William (Inventor); Basiji, David (Inventor); Bauer, Richard (Inventor); Liang, Luchuan (Inventor); Hall, Brian (Inventor); Perry, David (Inventor)

    2011-01-01

    A high speed, high-resolution flow imaging system is modified to achieve extended depth of field imaging. An optical distortion element is introduced into the flow imaging system. Light from an object, such as a cell, is distorted by the distortion element, such that a point spread function (PSF) of the imaging system is invariant across an extended depth of field. The distorted light is spectrally dispersed, and the dispersed light is used to simultaneously generate a plurality of images. The images are detected, and image processing is used to enhance the detected images by compensating for the distortion, to achieve extended depth of field images of the object. The post image processing preferably involves de-convolution, and requires knowledge of the PSF of the imaging system, as modified by the optical distortion element.

  15. Microinterferometer transducer

    DOEpatents

    Corey, III, Harry S.

    1979-01-01

    An air-bearing microinterferometer transducer is provided for increased accuracy, range and linearity over conventional displacement transducers. A microinterferometer system is housed within a small compartment of an air-bearing displacement transducer housing. A movable cube corner reflector of the interferometer is mounted to move with the displacement gauging probe of the transducer. The probe is disposed for axial displacement by means of an air-bearing. Light from a single frequency laser is directed into an interferometer system within the transducer housing by means of a self-focusing fiber optic cable to maintain light coherency. Separate fringe patterns are monitored by a pair of fiber optic cables which transmit the patterns to a detecting system. The detecting system includes a bidirectional counter which counts the light pattern fringes according to the direction of movement of the probe during a displacement gauging operation.

  16. System and process for detecting and monitoring surface defects

    NASA Technical Reports Server (NTRS)

    Mueller, Mark K. (Inventor)

    1994-01-01

    A system and process for detecting and monitoring defects in large surfaces such as the field joints of the container segments of a space shuttle booster motor. Beams of semi-collimated light from three non-parallel fiber optic light panels are directed at a region of the surface at non-normal angles of expected incidence. A video camera gathers some portion of the light that is reflected at an angle other than the angle of expected reflectance, and generates signals which are analyzed to discern defects in the surface. The analysis may be performed by visual inspection of an image on a video monitor, or by inspection of filtered or otherwise processed images. In one alternative embodiment, successive predetermined regions of the surface are aligned with the light source before illumination, thereby permitting efficient detection of defects in a large surface. Such alignment is performed by using a line scan gauge to sense the light which passes through an aperture in the surface. In another embodiment a digital map of the surface is created, thereby permitting the maintenance of records detailing changes in the location or size of defects as the container segment is refurbished and re-used. The defect detection apparatus may also be advantageously mounted on a fixture which engages the edge of a container segment.

  17. An integrated fluorescence detection system in poly(dimethylsiloxane) for microfluidic applications.

    PubMed

    Chabinyc, M L; Chiu, D T; McDonald, J C; Stroock, A D; Christian, J F; Karger, A M; Whitesides, G M

    2001-09-15

    This paper describes a prototype of an integrated fluorescence detection system that uses a microavalanche photodiode (microAPD) as the photodetector for microfluidic devices fabricated in poly(dimethylsiloxane) (PDMS). The prototype device consisted of a reusable detection system and a disposable microfluidic system that was fabricated using rapid prototyping. The first step of the procedure was the fabrication of microfluidic channels in PDMS and the encapsulation of a multimode optical fiber (100-microm core diameter) in the PDMS; the tip of the fiber was placed next to the side wall of one of the channels. The optical fiber was used to couple light into the microchannel for the excitation of fluorescent analytes. The photodetector, a prototype solid-state microAPD array, was embedded in a thick slab (1 cm) of PDMS. A thin (80 microm) colored polycarbonate filter was placed on the top of the embedded microAPD to absorb scattered excitation light before it reached the detector. The microAPD was placed below the microchannel and orthogonal to the axis of the optical fiber. The close proximity (approximately 200 microm) of the microAPD to the microchannel made it unnecessary to incorporate transfer optics; the pixel size of the microAPD (30 microm) matched the dimensions of the channels (50 microm). A blue light-emitting diode was used for fluorescence excitation. The microAPD was operated in Geiger mode to detect the fluorescence. The detection limit of the prototype (approximately 25 nM) was determined by finding the minimum detectable concentration of a solution of fluorescein. The device was used to detect the separation of a mixture of proteins and small molecules by capillary electrophoresis; the separation illustrated the suitability of this integrated fluorescence detection system for bioanalytical applications.

  18. Arrayed Micro-Ring Spectrometer System and Method of Use

    NASA Technical Reports Server (NTRS)

    Choi, Sang H. (Inventor); Park, Yeonjoon (Inventor); King, Glen C. (Inventor); Elliott, James R. (Inventor)

    2012-01-01

    A spectrometer system includes an array of micro-zone plates (MZP) each having coaxially-aligned ring gratings, a sample plate for supporting and illuminating a sample, and an array of photon detectors for measuring a spectral characteristic of the predetermined wavelength. The sample plate emits an evanescent wave in response to incident light, which excites molecules of the sample to thereby cause an emission of secondary photons. A method of detecting the intensity of a selected wavelength of incident light includes directing the incident light onto an array of MZP, diffracting a selected wavelength of the incident light onto a target focal point using the array of MZP, and detecting the intensity of the selected portion using an array of photon detectors. An electro-optic layer positioned adjacent to the array of MZP may be excited via an applied voltage to select the wavelength of the incident light.

  19. Pulsed-light imaging for fluorescence guided surgery under normal room lighting.

    PubMed

    Sexton, Kristian; Davis, Scott C; McClatchy, David; Valdes, Pablo A; Kanick, Stephen C; Paulsen, Keith D; Roberts, David W; Pogue, Brian W

    2013-09-01

    Fluorescence guided surgery (FGS) is an emerging technology that has demonstrated improved surgical outcomes. However, dim lighting conditions required by current FGS systems are disruptive to standard surgical workflow. We present a novel FGS system capable of imaging fluorescence under normal room light by using pulsed excitation and gated acquisition. Images from tissue-simulating phantoms confirm visual detection down to 0.25 μM of protoporphyrin IX under 125 μW/cm2 of ambient light, more than an order of magnitude lower than that measured with the Zeiss Pentero in the dark. Resection of orthotopic brain tumors in mice also suggests that the pulsed-light system provides superior sensitivity in vivo.

  20. Optical system for determining physical characteristics of a solar cell

    DOEpatents

    Sopori, Bhushan L.

    2001-01-01

    The invention provides an improved optical system for determining the physical characteristics of a solar cell. The system comprises a lamp means for projecting light in a wide solid-angle onto the surface of the cell; a chamber for receiving the light through an entrance port, the chamber having an interior light absorbing spherical surface, an exit port for receiving a beam of light reflected substantially normal to the cell, a cell support, and an lower aperture for releasing light into a light absorbing baffle; a means for dispersing the reflection into monochromatic components; a means for detecting an intensity of the components; and a means for reporting the determination.

  1. Surface-enhanced Raman detection of CW agents in water using gold sol gel substrates

    NASA Astrophysics Data System (ADS)

    Premasiri, W. Ranjith; Clarke, Richard H.; Womble, M. Edward

    2002-02-01

    The development of a water analysis system capable of detecting both inanimate trace chemical contaminants and viable microbial contaminants has long been a project of interest to our group. The capability of detecting both chemical and biological agent sources in a single device configuration would clearly add to the value of such a product. In the present work, we describe results with chemical warfare agents from our efforts to produce a Raman system for the detection of both chemical and biological warfare agents in water. We utilize laser Raman light scattering and employ Surface Enhanced Raman Spectroscopy (SERS)on solid state gold sol-gel detectors combined with fiber optic collection of the enhanced light signal in the sampling system to augment the normally low intensity Raman Scattering signal from trace materials.

  2. A low noise photoelectric signal acquisition system applying in nuclear magnetic resonance gyroscope

    NASA Astrophysics Data System (ADS)

    Lu, Qilin; Zhang, Xian; Zhao, Xinghua; Yang, Dan; Zhou, Binquan; Hu, Zhaohui

    2017-10-01

    The nuclear magnetic resonance gyroscope serves as a new generation of strong support for the development of high-tech weapons, it solves the core problem that limits the development of the long-playing seamless navigation and positioning. In the NMR gyroscope, the output signal with atomic precession frequency is detected by the probe light, the final crucial photoelectric signal of the probe light directly decides the quality of the gyro signal. But the output signal has high sensitivity, resolution and measurement accuracy for the photoelectric detection system. In order to detect the measured signal better, this paper proposed a weak photoelectric signal rapid acquisition system, which has high SNR and the frequency of responded signal is up to 100 KHz to let the weak output signal with high frequency of the NMR gyroscope can be detected better.

  3. Space Optical Communications Using Laser Beams

    NASA Technical Reports Server (NTRS)

    Goorjian, Peter M. (Inventor)

    2017-01-01

    A system for communicating between an object in space and a ground station, between objects in space, or between ground stations, includes a telecentric lens. Photodetectors positioned upon a focal plane of the telecentric lens detect an inbound light beam, received from a source, that has passed through the telecentric lens to the focal plane. Lasers positioned upon the focal plane transmit light beams from the focal plane through the telecentric lens to an area that includes the source of the inbound light beam. A processor detect signals from individual photodetectors corresponding to light detected, and selectively signals individual lasers that are close to those photodetectors, resulting in a returning beam that arrives close to the source, and which carries encoded data.

  4. Programmable near-infrared ranging system

    DOEpatents

    Everett, Jr., Hobart R.

    1989-01-01

    A high angular resolution ranging system particularly suitable for indoor plications involving mobile robot navigation and collision avoidance uses a programmable array of light emitters that can be sequentially incremented by a microprocessor. A plurality of adjustable level threshold detectors are used in an optical receiver for detecting the threshold level of the light echoes produced when light emitted from one or more of the emitters is reflected by a target or object in the scan path of the ranging system.

  5. Neural networks improve brain cancer detection with Raman spectroscopy in the presence of light artifacts

    NASA Astrophysics Data System (ADS)

    Jermyn, Michael; Desroches, Joannie; Mercier, Jeanne; St-Arnaud, Karl; Guiot, Marie-Christine; Petrecca, Kevin; Leblond, Frederic

    2016-03-01

    It is often difficult to identify cancer tissue during brain cancer (glioma) surgery. Gliomas invade into areas of normal brain, and this cancer invasion is frequently not detected using standard preoperative magnetic resonance imaging (MRI). This results in enduring invasive cancer following surgery and leads to recurrence. A hand-held Raman spectroscopy is able to rapidly detect cancer invasion in patients with grade 2-4 gliomas. However, ambient light sources can produce spectral artifacts which inhibit the ability to distinguish between cancer and normal tissue using the spectral information available. To address this issue, we have demonstrated that artificial neural networks (ANN) can accurately classify invasive cancer versus normal brain tissue, even when including measurements with significant spectral artifacts from external light sources. The non-parametric and adaptive model used by ANN makes it suitable for detecting complex non-linear spectral characteristics associated with different tissues and the confounding presence of light artifacts. The use of ANN for brain cancer detection with Raman spectroscopy, in the presence of light artifacts, improves the robustness and clinical translation potential for intraoperative use. Integration with the neurosurgical workflow is facilitated by accounting for the effect of light artifacts which may occur, due to operating room lights, neuronavigation systems, windows, or other light sources. The ability to rapidly detect invasive brain cancer under these conditions may reduce residual cancer remaining after surgery, and thereby improve patient survival.

  6. Electronic method for autofluorography of macromolecules on two-D matrices

    DOEpatents

    Davidson, Jackson B.; Case, Arthur L.

    1983-01-01

    A method for detecting, localizing, and quantifying macromolecules contained in a two-dimensional matrix is provided which employs a television-based position sensitive detection system. A molecule-containing matrix may be produced by conventional means to produce spots of light at the molecule locations which are detected by the television system. The matrix, such as a gel matrix, is exposed to an electronic camera system including an image-intensifier and secondary electron conduction camera capable of light integrating times of many minutes. A light image stored in the form of a charge image on the camera tube target is scanned by conventional television techniques, digitized, and stored in a digital memory. Intensity of any point on the image may be determined from the number at the memory address of the point. The entire image may be displayed on a television monitor for inspection and photographing or individual spots may be analyzed through selected readout of the memory locations. Compared to conventional film exposure methods, the exposure time may be reduced 100-1000 times.

  7. Far-ultraviolet absorbance detection of sugars and peptides by high-performance liquid chromatography.

    PubMed

    Uchiho, Yuichi; Goto, Yusuke; Kamahori, Masao; Aota, Toshimichi; Morisaki, Atsuki; Hosen, Yusuke; Koda, Kimiyoshi

    2015-12-11

    A far-ultraviolet (FUV)-absorbance detector with a transmission flow cell was developed and applied to detect absorbance of sugars and peptides by HPLC. The main inherent limitation of FUV-absorbance detection is the strong absorptions of solvents and atmospheric oxygen in the optical system as well as dissolved oxygen in the solvent. High absorptivity of the solvent and oxygen decreases transmission-light intensity in the flow cell and hinders the absorbance measurement. To solve the above drawbacks, the transmission-light intensity in the flow cell was increased by introducing a new optical system and a nitrogen-purging unit to remove the atmospheric oxygen. The optical system has a photodiode for detecting the reference light at a position of the minus-first-order diffracted light. In addition, acetonitrile and water were selected as usable solvents because of their low absorptivity in the FUV region. As a result of these implementations, the detectable wavelength of the FUV-absorbance detector (with a flow cell having an effective optical path length of 0.5mm) can be extended down to 175nm. Three sugars (glucose, fructose, and sucrose) were successfully detected with the FUV-absorbance detector. These detection results reveal that the absorption peak of sugar in liquid phase lies at around 178nm. The detection limit (S/N=3) in absorbance with a 0.5-mm flow cell at 180nm was 21μAU, which corresponds to 33, 60 and 60μM (198, 360, and 360pmol) for fructose, glucose, and sucrose, respectively. Also, the peptide Met-enkephalin could be detected with a high sensitivity at 190nm. The estimated detection limit (S/N=3) for Met-enkephalin is 29nM (0.29pmol), which is eight times lower than that at 220nm. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. Reaction times to weak test lights. [psychophysics biological model

    NASA Technical Reports Server (NTRS)

    Wandell, B. A.; Ahumada, P.; Welsh, D.

    1984-01-01

    Maloney and Wandell (1984) describe a model of the response of a single visual channel to weak test lights. The initial channel response is a linearly filtered version of the stimulus. The filter output is randomly sampled over time. Each time a sample occurs there is some probability increasing with the magnitude of the sampled response - that a discrete detection event is generated. Maloney and Wandell derive the statistics of the detection events. In this paper a test is conducted of the hypothesis that the reaction time responses to the presence of a weak test light are initiated at the first detection event. This makes it possible to extend the application of the model to lights that are slightly above threshold, but still within the linear operating range of the visual system. A parameter-free prediction of the model proposed by Maloney and Wandell for lights detected by this statistic is tested. The data are in agreement with the prediction.

  9. Research on detecting heterogeneous fibre from cotton based on linear CCD camera

    NASA Astrophysics Data System (ADS)

    Zhang, Xian-bin; Cao, Bing; Zhang, Xin-peng; Shi, Wei

    2009-07-01

    The heterogeneous fibre in cotton make a great impact on production of cotton textile, it will have a bad effect on the quality of product, thereby affect economic benefits and market competitive ability of corporation. So the detecting and eliminating of heterogeneous fibre is particular important to improve machining technics of cotton, advance the quality of cotton textile and reduce production cost. There are favorable market value and future development for this technology. An optical detecting system obtains the widespread application. In this system, we use a linear CCD camera to scan the running cotton, then the video signals are put into computer and processed according to the difference of grayscale, if there is heterogeneous fibre in cotton, the computer will send an order to drive the gas nozzle to eliminate the heterogeneous fibre. In the paper, we adopt monochrome LED array as the new detecting light source, it's lamp flicker, stability of luminous intensity, lumens depreciation and useful life are all superior to fluorescence light. We analyse the reflection spectrum of cotton and various heterogeneous fibre first, then select appropriate frequency of the light source, we finally adopt violet LED array as the new detecting light source. The whole hardware structure and software design are introduced in this paper.

  10. The ANTARES optical beacon system

    NASA Astrophysics Data System (ADS)

    Ageron, M.; Aguilar, J. A.; Albert, A.; Ameli, F.; Anghinolfi, M.; Anton, G.; Anvar, S.; Ardellier-Desages, F.; Aslanides, E.; Aubert, J.-J.; Auer, R.; Barbarito, E.; Basa, S.; Battaglieri, M.; Becherini, Y.; Beltramelli, J.; Bertin, V.; Bigi, A.; Billault, M.; Blaes, R.; de Botton, N.; Bouwhuis, M. C.; Bradbury, S. M.; Bruijn, R.; Brunner, J.; Burgio, G. F.; Busto, J.; Cafagna, F.; Caillat, L.; Calzas, A.; Capone, A.; Caponetto, L.; Carmona, E.; Carr, J.; Cartwright, S. L.; Castel, D.; Castorina, E.; Cavasinni, V.; Cecchini, S.; Ceres, A.; Charvis, P.; Chauchot, P.; Chiarusi, T.; Circella, M.; Colnard, C.; Compère, C.; Coniglione, R.; Cottini, N.; Coyle, P.; Cuneo, S.; Cussatlegras, A.-S.; Damy, G.; van Dantzig, R.; de Bonis, G.; de Marzo, C.; de Vita, R.; Dekeyser, I.; Delagnes, E.; Denans, D.; Deschamps, A.; Destelle, J.-J.; Dinkespieler, B.; Distefano, C.; Donzaud, C.; Drogou, J.-F.; Druillole, F.; Durand, D.; Ernenwein, J.-P.; Escoffier, S.; Falchini, E.; Favard, S.; Fehr, F.; Feinstein, F.; Ferry, S.; Fiorello, C.; Flaminio, V.; Fratini, K.; Fuda, J.-L.; Galeotti, S.; Gallone, J.-M.; Giacomelli, G.; Girard, N.; Gojak, C.; Goret, Ph.; Graf, K.; Hallewell, G.; Harakeh, M. N.; Hartmann, B.; Heijboer, A.; Heine, E.; Hello, Y.; Hernández-Rey, J. J.; Hößl, J.; Hoffman, C.; Hogenbirk, J.; Hubbard, J. R.; Jaquet, M.; Jaspers, M.; de Jong, M.; Jouvenot, F.; Kalantar-Nayestanaki, N.; Kappes, A.; Karg, T.; Katz, U.; Keller, P.; Kok, E.; Kok, H.; Kooijman, P.; Kopper, C.; Korolkova, E. V.; Kouchner, A.; Kretschmer, W.; Kruijer, A.; Kuch, S.; Kudryavstev, V. A.; Lagier, P.; Lahmann, R.; Lamanna, G.; Lamare, P.; Lambard, G.; Languillat, J.-C.; Laschinsky, H.; Lavalle, J.; Le Guen, Y.; Le Provost, H.; Le van Suu, A.; Lefèvre, D.; Legou, T.; Lelaizant, G.; Lim, G.; Lo Presti, D.; Loehner, H.; Loucatos, S.; Louis, F.; Lucarelli, F.; Lyashuk, V.; Marcelin, M.; Margiotta, A.; Masullo, R.; Mazéas, F.; Mazure, A.; McMillan, J. E.; Megna, R.; Melissas, M.; Migneco, E.; Milovanovic, A.; Mongelli, M.; Montaruli, T.; Morganti, M.; Moscoso, L.; Musumeci, M.; Naumann-Godo, M.; Naumann, C.; Niess, V.; Noble, T.; Olivetto, C.; Ostasch, R.; Palanque-Delabrouille, N.; Payre, P.; Peek, H.; Perez, A.; Petta, C.; Piattelli, P.; Pillet, R.; Pineau, J.-P.; Poinsignon, J.; Popa, V.; Pradier, T.; Racca, C.; Randazzo, N.; van Randwijk, J.; Real, D.; van Rens, B.; Réthoré, F.; Rewiersma, P.; Riccobene, G.; Rigaud, V.; Ripani, M.; Roca, V.; Roda, C.; Rolin, J. F.; Rose, H. J.; Rostovtsev, A.; Roux, J.; Ruppi, M.; Russo, G. V.; Rusydi, G.; Salesa, F.; Salomon, K.; Sapienza, P.; Schmitt, F.; Schuller, J.-P.; Shanidze, R.; Sokalski, I.; Spona, T.; Spurio, M.; van der Steenhoven, G.; Stolarczyk, T.; Streeb, K.; Sulak, L.; Taiuti, M.; Tamburini, C.; Tao, C.; Terreni, G.; Thompson, L. F.; Urbano, F.; Valdy, P.; Valente, V.; Vallage, B.; Vaudaine, G.; Venekamp, G.; Verlaat, B.; Vernin, P.; de Vries-Uiterweerd, G.; van Wijk, R.; Wijnker, G.; de Witt Huberts, P.; Wobbe, G.; de Wolf, E.; Yao, A.-F.; Zaborov, D.; Zaccone, H.; Zornoza, J. D.; Zúñiga, J.

    2007-08-01

    ANTARES is a neutrino telescope being deployed in the Mediterranean Sea. It consists of a three-dimensional array of photomultiplier tubes that can detect the Cherenkov light induced by charged particles produced in the interactions of neutrinos with the surrounding medium. High angular resolution can be achieved, in particular, when a muon is produced, provided that the Cherenkov photons are detected with sufficient timing precision. Considerations of the intrinsic time uncertainties stemming from the transit time spread in the photomultiplier tubes and the mechanism of transmission of light in sea water lead to the conclusion that a relative time accuracy of the order of 0.5 ns is desirable. Accordingly, different time calibration systems have been developed for the ANTARES telescope. In this article, a system based on Optical Beacons, a set of external and well-controlled pulsed light sources located throughout the detector, is described. This calibration system takes into account the optical properties of sea water, which is used as the detection volume of the ANTARES telescope. The design, tests, construction and first results of the two types of beacons, LED and laser-based, are presented.

  11. Few-mode fiber detection for tissue characterization in optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Eugui, Pablo; Lichtenegger, Antonia; Augustin, Marco; Harper, Danielle J.; Fialová, Stanislava; Wartak, Andreas; Hitzenberger, Christoph K.; Baumann, Bernhard

    2017-07-01

    A few-mode fiber based detection for OCT systems is presented. The capability of few-mode fibers for delivering light through different fiber paths enables the application of these fibers for angular scattering tissue character- ization. Since the optical path lengths traveled in the fiber change between the fiber modes, the OCT image information will be reconstructed at different depth positions, separating the directly backscattered light from the light scattered at other angles. Using the proposed method, the relation between the angle of reflection from the sample and the respective modal intensity distribution was investigated. The system was demonstrated for imaging ex-vivo brain tissue samples of patients with Alzheimer's disease.

  12. Hanging drop crystal growth apparatus

    NASA Technical Reports Server (NTRS)

    Naumann, Robert J. (Inventor); Witherow, William K. (Inventor); Carter, Daniel C. (Inventor); Bugg, Charles E. (Inventor); Suddath, Fred L. (Inventor)

    1990-01-01

    This invention relates generally to control systems for controlling crystal growth, and more particularly to such a system which uses a beam of light refracted by the fluid in which crystals are growing to detect concentration of solutes in the liquid. In a hanging drop apparatus, a laser beam is directed onto drop which refracts the laser light into primary and secondary bows, respectively, which in turn fall upon linear diode detector arrays. As concentration of solutes in drop increases due to solvent removal, these bows move farther apart on the arrays, with the relative separation being detected by arrays and used by a computer to adjust solvent vapor transport from the drop. A forward scattering detector is used to detect crystal nucleation in drop, and a humidity detector is used, in one embodiment, to detect relative humidity in the enclosure wherein drop is suspended. The novelty of this invention lies in utilizing angular variance of light refracted from drop to infer, by a computer algorithm, concentration of solutes therein. Additional novelty is believed to lie in using a forward scattering detector to detect nucleating crystallites in drop.

  13. Proximal design for a multimodality endoscope with multiphoton microscopy, optical coherence microscopy and visual modalities

    NASA Astrophysics Data System (ADS)

    Kiekens, Kelli C.; Talarico, Olivia; Barton, Jennifer K.

    2018-02-01

    A multimodality endoscope system has been designed for early detection of ovarian cancer. Multiple illumination and detection systems must be integrated in a compact, stable, transportable configuration to meet the requirements of a clinical setting. The proximal configuration presented here supports visible light navigation with a large field of view and low resolution, high resolution multiphoton microscopy (MPM), and high resolution optical coherence microscopy (OCM). All modalities are integrated into a single optical system in the endoscope. The system requires two light sources: a green laser for visible light navigation and a compact fiber based femtosecond laser for MPM and OCM. Using an inline wavelength division multiplexer, the two sources are combined into a single mode fiber. To accomplish OCM, a fiber coupler is used to separate the femtosecond laser into a reference arm and signal arm. The reflected reference arm and the signal from the sample are interfered and wavelength separated by a reflection grating and detected using a linear array. The MPM signal is collimated and goes through a series of filters to separate the 2nd and 3rd harmonics as well as twophoton excitation florescence (2PEF) and 3PEF. Each signal is independently detected on a photo multiplier tube and amplified. The visible light is collected by multiple high numerical aperture fibers at the endoscope tip which are bundled into one SMA adapter at the proximal end and connected to a photodetector. This integrated system design is compact, efficient and meets both optical and mechanical requirements for clinical applications.

  14. Monitoring forests at the speed of light.

    Treesearch

    Valerie Rapp

    2005-01-01

    Airborne laser scanning is a technology developed in the last 15 years. Commonly referred to as light detection and ranging, or LIDAR, these systems can map ground with up to a 6-inch elevation accuracy in open, flat terrain. LIDAR is being rapidly adopted for topographical and flood-plain mapping and the detection of earthquake faults hidden by vegetation, among other...

  15. Method and apparatus for determining the physical properties of materials using dynamic light scattering techniques

    NASA Technical Reports Server (NTRS)

    Dhadwal, Harbans S. (Inventor)

    1992-01-01

    A system for determining the physical properties of materials through the use of dynamic light scattering is disclosed. The system includes a probe, a laser source for directing a laser beam into the probe, and a photodetector for converting scattered light detected by the probe into electrical signals. The probe includes at least one optical fiber connected to the laser source and a second optical fiber connected to the photodetector. Each of the fibers may adjoin a gradient index microlens which is capable of providing a collimated laser beam into a scattering medium. The position of the second optical fiber with respect to the optical axis of the probe determines whether homodyne or self-beating detection is provided. Self-beating detection may be provided without a gradient index microlens. This allows a very small probe to be constructed which is insertable through a hypodermic needle or the like into a droplet extending from such a needle. A method of detecting scattered light through the use of a collimated, Gaussian laser beam is also provided. A method for controlling the waist and divergence of the optical field emanating from the free end of an optical fiber is also provided.

  16. Optochemical sensor based on screenprinted fluorescent sensorspots surrounded by organic photodiodes for multianalyte detection

    NASA Astrophysics Data System (ADS)

    Kraker, E.; Lamprecht, B.; Haase, A.; Jakopic, G.; Abel, T.; Konrad, C.; Köstler, S.; Tscherner, M.; Stadlober, B.; Mayr, T.

    2010-08-01

    A compact, integrated photoluminescence based oxygen sensor, utilizing an organic light emitting device (OLED) as the light source and an organic photodiode (OPD) as the detection unit, is described. The detection system of the sensor array consists of an array of circular screen-printed fluorescent sensor spots surrounded by organic photodiodes as integrated fluorescence detectors. The OPD originates from the well-known Tang photodiode, consisting of a stacked layer of copper phthalocyanine (CuPc, p-type material) and perylene tetracarboxylic bisbenzimidazole (PTCBi, n-type material). An additional layer of tris-8-hydroxyquinolinatoaluminium (Alq3, n-type material) was inserted between the PTCBi layer and cathode. An ORMOCERR layer was used as encapsulation layer. For excitation an organic light emitting diode is used. The sensor spot and the detector are processed on the same flexible substrate. This approach not only simplifies the detection system by minimizing the numbers of required optical components - no optical filters have to be used for separating the excitation light and the luminescent emission-, but also has a large potential for low-cost sensor applications. The feasibility of the concept is demonstrated by an integrated oxygen sensor, indicating good performance. Sensor schemes for other chemical parameters are proposed.

  17. Ellipsoidal cell flow system

    DOEpatents

    Salzman, Gary C.; Mullaney, Paul F.

    1976-01-01

    The disclosure relates to a system incorporating an ellipsoidal flow chamber having light reflective walls for low level light detection in practicing cellular analysis. The system increases signal-to-noise ratio by a factor of ten over prior art systems. In operation, laser light passes through the primary focus of the ellipsoid. A controlled flow of cells simultaneously passes through this focus so that the laser light impinges on the cells and is modulated by the cells. The reflective walls of the ellipsoid reflect the cell-modulated light to the secondary focus of the ellipsoid. A tapered light guide at the secondary focus picks up a substantial portion of modulated reflective light and directs it onto a light detector to produce a signal. The signal is processed to obtain the intensity distribution of the modulated light and hence sought after characteristics of the cells. In addition, cells may be dyed so as to fluoresce in response to the laser light and their fluorescence may be processed as cell-modulated light above described. A light discriminating filter would be used to distinguish reflected modulated laser light from reflected fluorescent light.

  18. Imaging System and Method for Biomedical Analysis

    DTIC Science & Technology

    2013-03-11

    biological particles and items of interest. Broadly, Padmanabhan et al. utilize the diffraction of a laser light source in flow cytometry to count...spread of light from multiple LED devices over the entire sample surface. Preferably, light source 308 projects a full spectrum white light. Light...for example, red blood cells, white blood cells (which may include lymphocytes which are relatively large and easily detectable), T-helper cells

  19. Wavefront detection method of a single-sensor based adaptive optics system.

    PubMed

    Wang, Chongchong; Hu, Lifa; Xu, Huanyu; Wang, Yukun; Li, Dayu; Wang, Shaoxin; Mu, Quanquan; Yang, Chengliang; Cao, Zhaoliang; Lu, Xinghai; Xuan, Li

    2015-08-10

    In adaptive optics system (AOS) for optical telescopes, the reported wavefront sensing strategy consists of two parts: a specific sensor for tip-tilt (TT) detection and another wavefront sensor for other distortions detection. Thus, a part of incident light has to be used for TT detection, which decreases the light energy used by wavefront sensor and eventually reduces the precision of wavefront correction. In this paper, a single Shack-Hartmann wavefront sensor based wavefront measurement method is presented for both large amplitude TT and other distortions' measurement. Experiments were performed for testing the presented wavefront method and validating the wavefront detection and correction ability of the single-sensor based AOS. With adaptive correction, the root-mean-square of residual TT was less than 0.2 λ, and a clear image was obtained in the lab. Equipped on a 1.23-meter optical telescope, the binary stars with angle distance of 0.6″ were clearly resolved using the AOS. This wavefront measurement method removes the separate TT sensor, which not only simplifies the AOS but also saves light energy for subsequent wavefront sensing and imaging, and eventually improves the detection and imaging capability of the AOS.

  20. Development of a Novel Optical Biosensor for Detection of Organophoshorus Pesticides Based on Methyl Parathion Hydrolase Immobilized by Metal-Chelate Affinity

    PubMed Central

    Lan, Wensheng; Chen, Guoping; Cui, Feng; Tan, Feng; Liu, Ran; Yushupujiang, Maolidan

    2012-01-01

    We have developed a novel optical biosensor device using recombinant methyl parathion hydrolase (MPH) enzyme immobilized on agarose by metal-chelate affinity to detect organophosphorus (OP) compounds with a nitrophenyl group. The biosensor principle is based on the optical measurement of the product of OP catalysis by MPH (p-nitrophenol). Briefly, MPH containing six sequential histidines (6× His tag) at its N-terminal was bound to nitrilotriacetic acid (NTA) agarose with Ni ions, resulting in the flexible immobilization of the bio-reaction platform. The optical biosensing system consisted of two light-emitting diodes (LEDs) and one photodiode. The LED that emitted light at the wavelength of the maximum absorption for p-nitrophenol served as the signal light, while the other LED that showed no absorbance served as the reference light. The optical sensing system detected absorbance that was linearly correlated to methyl parathion (MP) concentration and the detection limit was estimated to be 4 μM. Sensor hysteresis was investigated and the results showed that at lower concentration range of MP the difference got from the opposite process curves was very small. With its easy immobilization of enzymes and simple design in structure, the system has the potential for development into a practical portable detector for field applications. PMID:23012501

  1. Detection of endometrial lesions by degree of linear polarization maps

    NASA Astrophysics Data System (ADS)

    Kim, Jihoon; Fazleabas, Asgerally; Walsh, Joseph T.

    2010-02-01

    Endometriosis is one of the most common causes of chronic pelvic pain and infertility and is characterized by the presence of endometrial glands and stroma outside of the uterine cavity. A novel laparoscopic polarization imaging system was designed to detect endometriosis by imaging endometrial lesions. Linearly polarized light with varying incident polarization angles illuminated endometrial lesions. Degree of linear polarization image maps of endometrial lesions were constructed by using remitted polarized light. The image maps were compared with regular laparoscopy image. The degree of linear polarization map contributed to the detection of endometriosis by revealing structures inside the lesion. The utilization of rotating incident polarization angle (IPA) for the linearly polarized light provides extended understanding of endometrial lesions. The developed polarization system with varying IPA and the collected image maps could provide improved characterization of endometrial lesions via higher visibility of the structure of the lesions and thereby improve diagnosis of endometriosis.

  2. Design considerations for highly effective fluorescence excitation and detection optical systems for molecular diagnostics

    NASA Astrophysics Data System (ADS)

    Kasper, Axel; Van Hille, Herbert; Kuk, Sola

    2018-02-01

    Modern instruments for molecular diagnostics are continuously optimized for diagnostic accuracy, versatility and throughput. The latest progress in LED technology together with tailored optics solutions allows developing highly efficient photonics engines perfectly adapted to the sample under test. Super-bright chip-on-board LED light sources are a key component for such instruments providing maximum luminous intensities in a multitude of narrow spectral bands. In particular the combination of white LEDs with other narrow band LEDs allows achieving optimum efficiency outperforming traditional Xenon light sources in terms of energy consumption, heat dissipation in the system, and switching time between spectral channels. Maximum sensitivity of the diagnostic system can only be achieved with an optimized optics system for the illumination and imaging of the sample. The illumination beam path must be designed for optimum homogeneity across the field while precisely limiting the angular distribution of the excitation light. This is a necessity for avoiding spill-over to the detection beam path and guaranteeing the efficiency of the spectral filtering. The imaging optics must combine high spatial resolution, high light collection efficiency and optimized suppression of excitation light for good signal-to-noise ratio. In order to achieve minimum cross-talk between individual wells in the sample, the optics design must also consider the generation of stray light and the formation of ghost images. We discuss what parameters and limitations have to be considered in an integrated system design approach covering the full path from the light source to the detector.

  3. Room-temperature quantum noise limited spectrometry and methods of the same

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stevens, Charles G.; Tringe, Joseph W.; Cunningham, Christopher T.

    According to one embodiment, a heterodyne detection system for detecting light, includes: a first input aperture configured to receive first light from a scene input; a second input aperture configured to receive second light from a local oscillator input; a broadband local oscillator configured to provide the second light to the second input aperture; a dispersive element configured to disperse the first light and the second light; and a final condensing lens coupled to a detector. The final condensing lens is configured to concentrate incident light from a primary condensing lens onto the detector. The detector is configured to sensemore » a frequency difference between the first light and the second light; and the final condensing lens comprises a plasmonic condensing lens. Methods for forming a plasmonic condensing lens to enable room temperature quantum noise limited spectrometry are also disclosed.« less

  4. Increasing the efficiency of photon collection in LArTPCs: the ARAPUCA light trap

    NASA Astrophysics Data System (ADS)

    Cancelo, G.; Cavanna, F.; Escobar, C. O.; Kemp, E.; Machado, A. A.; Para, A.; Segreto, E.; Totani, D.; Warner, D.

    2018-03-01

    The Liquid Argon Time Projection Chambers (LArTPCs) are a choice for the next generation of large neutrino detectors due to their optimal performance in particle tracking and calorimetry. The detection of Argon scintillation light plays a crucial role in the event reconstruction as well as the time reference for non-beam physics such as supernovae neutrino detection and baryon number violation studies. In this contribution, we present the current R&D work on the ARAPUCA (Argon R&D Advanced Program at UNICAMP), a light trap device to enhance Ar scintillation light collection and thus the overall performance of LArTPCs. The ARAPUCA working principle is based on a suitable combination of dichroic filters and wavelength shifters to achieve a high efficiency in light collection. We discuss the operational principles, the last results of laboratory tests and the application of the ARAPUCA as the alternative photon detection system in the protoDUNE detector.

  5. Regression analysis for LED color detection of visual-MIMO system

    NASA Astrophysics Data System (ADS)

    Banik, Partha Pratim; Saha, Rappy; Kim, Ki-Doo

    2018-04-01

    Color detection from a light emitting diode (LED) array using a smartphone camera is very difficult in a visual multiple-input multiple-output (visual-MIMO) system. In this paper, we propose a method to determine the LED color using a smartphone camera by applying regression analysis. We employ a multivariate regression model to identify the LED color. After taking a picture of an LED array, we select the LED array region, and detect the LED using an image processing algorithm. We then apply the k-means clustering algorithm to determine the number of potential colors for feature extraction of each LED. Finally, we apply the multivariate regression model to predict the color of the transmitted LEDs. In this paper, we show our results for three types of environmental light condition: room environmental light, low environmental light (560 lux), and strong environmental light (2450 lux). We compare the results of our proposed algorithm from the analysis of training and test R-Square (%) values, percentage of closeness of transmitted and predicted colors, and we also mention about the number of distorted test data points from the analysis of distortion bar graph in CIE1931 color space.

  6. Advances in detection of diffuse seafloor venting using structured light imaging.

    NASA Astrophysics Data System (ADS)

    Smart, C.; Roman, C.; Carey, S.

    2016-12-01

    Systematic, remote detection and high resolution mapping of low temperature diffuse hydrothermal venting is inefficient and not currently tractable using traditional remotely operated vehicle (ROV) mounted sensors. Preliminary results for hydrothermal vent detection using a structured light laser sensor were presented in 2011 and published in 2013 (Smart) with continual advancements occurring in the interim. As the structured light laser passes over active venting, the projected laser line effectively blurs due to the associated turbulence and density anomalies in the vent fluid. The degree laser disturbance is captured by a camera collecting images of the laser line at 20 Hz. Advancements in the detection of the laser and fluid interaction have included extensive normalization of the collected laser data and the implementation of a support vector machine algorithm to develop a classification routine. The image data collected over a hydrothermal vent field is then labeled as seafloor, bacteria or a location of venting. The results can then be correlated with stereo images, bathymetry and backscatter data. This sensor is a component of an ROV mounted imaging suite which also includes stereo cameras and a multibeam sonar system. Originally developed for bathymetric mapping, the structured light laser sensor, and other imaging suite components, are capable of creating visual and bathymetric maps with centimeter level resolution. Surveys are completed in a standard mowing the lawn pattern completing a 30m x 30m survey with centimeter level resolution in under an hour. Resulting co-registered data includes, multibeam and structured light laser bathymetry and backscatter, stereo images and vent detection. This system allows for efficient exploration of areas with diffuse and small point source hydrothermal venting increasing the effectiveness of scientific sampling and observation. Recent vent detection results collected during the 2013-2015 E/V Nautilus seasons will be presented. Smart, C. J. and Roman, C. and Carey, S. N. (2013) Detection of diffuse seafloor venting using structured light imaging, Geochemistry, Geophysics, Geosystems, 14, 4743-4757

  7. Investigating the real translucency of the endodontic fiber posts

    NASA Astrophysics Data System (ADS)

    Camilotti, Fernando; Bonardi, Cláudia; Somer, Aloisi; Novatski, Andressa; Szesz, Anna Luiza; Loguércio, Alessandro Dourado; Kniphoff da Cruz, Gerson

    2018-02-01

    Researchers have been investigating the light intensity scattered by a translucent fiber post with application in dentistry by different methods. In this work, we introduce a new system capable to record a light scattered profile, step-by-step, as a function of the length of the translucent fiber post. To support our studies, an extensive characterization of the system was carried out and this is presented and discussed here. The system was implemented using the phase sensitive detection. The equipment measures the light scattered without the need of any preparing parts and the fiber post is fixed directly in the fiber post holder becoming ready for measurement. Measures can be recorded with a spatial resolution smaller than 0.01 mm throughout the length of the fiber post being investigated. The system was implemented by using a photomultiplier tube that improves sensitivity for the optical detection. The recorded result is a signal directly proportional to the scattered light and it allows us to obtain a normalized profile that can be used as a map of the scattered light of the fiber post in study. Furthermore, we are able to demonstrate a low intensity of light in the tip region of the fiber post, along with the dependency of the light attenuation with the fiber post body volume and shape. This new system will certainly contribute to achieve better results in fiber post designing and in restoration of endodontic treated teeth because it provides a more well-founded choice of the fiber post to be used, and of the time of exposure to the curing light.

  8. Optical system and method for gas detection and monitoring

    NASA Technical Reports Server (NTRS)

    Polzin, Kurt A. (Inventor); Sinko, John Elihu (Inventor); Korman, Valentin (Inventor); Witherow, William K. (Inventor); Hendrickson, Adam Gail (Inventor)

    2011-01-01

    A free-space optical path of an optical interferometer is disposed in an environment of interest. A light beam is guided to the optical interferometer using a single-mode optical fiber. The light beam traverses the interferometer's optical path. The light beam guided to the optical path is combined with the light beam at the end of the optical path to define an output light. A temporal history of the output light is recorded.

  9. High Resolution Trichromatic Road Surface Scanning with a Line Scan Camera and Light Emitting Diode Lighting for Road-Kill Detection.

    PubMed

    Lopes, Gil; Ribeiro, A Fernando; Sillero, Neftalí; Gonçalves-Seco, Luís; Silva, Cristiano; Franch, Marc; Trigueiros, Paulo

    2016-04-19

    This paper presents a road surface scanning system that operates with a trichromatic line scan camera with light emitting diode (LED) lighting achieving road surface resolution under a millimeter. It was part of a project named Roadkills-Intelligent systems for surveying mortality of amphibians in Portuguese roads, sponsored by the Portuguese Science and Technology Foundation. A trailer was developed in order to accommodate the complete system with standalone power generation, computer image capture and recording, controlled lighting to operate day or night without disturbance, incremental encoder with 5000 pulses per revolution attached to one of the trailer wheels, under a meter Global Positioning System (GPS) localization, easy to utilize with any vehicle with a trailer towing system and focused on a complete low cost solution. The paper describes the system architecture of the developed prototype, its calibration procedure, the performed experimentation and some obtained results, along with a discussion and comparison with existing systems. Sustained operating trailer speeds of up to 30 km/h are achievable without loss of quality at 4096 pixels' image width (1 m width of road surface) with 250 µm/pixel resolution. Higher scanning speeds can be achieved by lowering the image resolution (120 km/h with 1 mm/pixel). Computer vision algorithms are under development to operate on the captured images in order to automatically detect road-kills of amphibians.

  10. High Resolution Trichromatic Road Surface Scanning with a Line Scan Camera and Light Emitting Diode Lighting for Road-Kill Detection

    PubMed Central

    Lopes, Gil; Ribeiro, A. Fernando; Sillero, Neftalí; Gonçalves-Seco, Luís; Silva, Cristiano; Franch, Marc; Trigueiros, Paulo

    2016-01-01

    This paper presents a road surface scanning system that operates with a trichromatic line scan camera with light emitting diode (LED) lighting achieving road surface resolution under a millimeter. It was part of a project named Roadkills—Intelligent systems for surveying mortality of amphibians in Portuguese roads, sponsored by the Portuguese Science and Technology Foundation. A trailer was developed in order to accommodate the complete system with standalone power generation, computer image capture and recording, controlled lighting to operate day or night without disturbance, incremental encoder with 5000 pulses per revolution attached to one of the trailer wheels, under a meter Global Positioning System (GPS) localization, easy to utilize with any vehicle with a trailer towing system and focused on a complete low cost solution. The paper describes the system architecture of the developed prototype, its calibration procedure, the performed experimentation and some obtained results, along with a discussion and comparison with existing systems. Sustained operating trailer speeds of up to 30 km/h are achievable without loss of quality at 4096 pixels’ image width (1 m width of road surface) with 250 µm/pixel resolution. Higher scanning speeds can be achieved by lowering the image resolution (120 km/h with 1 mm/pixel). Computer vision algorithms are under development to operate on the captured images in order to automatically detect road-kills of amphibians. PMID:27104535

  11. Ocular static and dynamic light scattering: a noninvasive diagnostic tool for eye research and clinical practice

    NASA Technical Reports Server (NTRS)

    Ansari, Rafat R.

    2004-01-01

    The noninvasive techniques of static and dynamic light scattering are emerging as valuable diagnostic tools for the early detection of ocular and systemic diseases. These include corneal abnormalities, pigmentary dispersion syndrome, glaucoma, cataract, diabetic vitreopathy, and possibly macular degeneration. Systemic conditions such as diabetes and possibly Alzheimer's disease can potentially be detected early via ocular tissues. The current state of development of these techniques for application to ophthalmic research and ultimately clinical practice is reviewed. (c) 2004 Society of Photo-Optical Instrumentation Engineers.

  12. Enhancing swimming pool safety by the use of range-imaging cameras

    NASA Astrophysics Data System (ADS)

    Geerardyn, D.; Boulanger, S.; Kuijk, M.

    2015-05-01

    Drowning is the cause of death of 372.000 people, each year worldwide, according to the report of November 2014 of the World Health Organization.1 Currently, most swimming pools only use lifeguards to detect drowning people. In some modern swimming pools, camera-based detection systems are nowadays being integrated. However, these systems have to be mounted underwater, mostly as a replacement of the underwater lighting. In contrast, we are interested in range imaging cameras mounted on the ceiling of the swimming pool, allowing to distinguish swimmers at the surface from drowning people underwater, while keeping the large field-of-view and minimizing occlusions. However, we have to take into account that the water surface of a swimming pool is not a flat, but mostly rippled surface, and that the water is transparent for visible light, but less transparent for infrared or ultraviolet light. We investigated the use of different types of 3D cameras to detect objects underwater at different depths and with different amplitudes of surface perturbations. Specifically, we performed measurements with a commercial Time-of-Flight camera, a commercial structured-light depth camera and our own Time-of-Flight system. Our own system uses pulsed Time-of-Flight and emits light of 785 nm. The measured distances between the camera and the object are influenced through the perturbations on the water surface. Due to the timing of our Time-of-Flight camera, our system is theoretically able to minimize the influence of the reflections of a partially-reflecting surface. The combination of a post image-acquisition filter compensating for the perturbations and the use of a light source with shorter wavelengths to enlarge the depth range can improve the current commercial cameras. As a result, we can conclude that low-cost range imagers can increase swimming pool safety, by inserting a post-processing filter and the use of another light source.

  13. Pulsed-light imaging for fluorescence guided surgery under normal room lighting

    PubMed Central

    Sexton, Kristian; Davis, Scott C.; McClatchy, David; Valdes, Pablo A.; Kanick, Stephen C.; Paulsen, Keith D.; Roberts, David W.; Pogue, Brian W.

    2013-01-01

    Fluorescence guided surgery (FGS) is an emerging technology that has demonstrated improved surgical outcomes. However, dim lighting conditions required bycurrent FGS systems are disruptive to standard surgical workflow. We present a novel FGS system capable of imaging fluorescence under normal room lightby using pulsed excitation and gated acquisition. Images from tissue-simulating phantoms confirm visual detection down to 0.25 μM of protopor-phyrin IX under 125 μW/cm2 of ambient light, more than an order of magnitude lower than that measured with the Zeiss Pentero in the dark. Resection of orthotopic brain tumors in mice also suggests that the pulsed-light system provides superior sensitivity in vivo. PMID:23988926

  14. On-chip detection of non-classical light by scalable integration of single-photon detectors

    PubMed Central

    Najafi, Faraz; Mower, Jacob; Harris, Nicholas C.; Bellei, Francesco; Dane, Andrew; Lee, Catherine; Hu, Xiaolong; Kharel, Prashanta; Marsili, Francesco; Assefa, Solomon; Berggren, Karl K.; Englund, Dirk

    2015-01-01

    Photonic-integrated circuits have emerged as a scalable platform for complex quantum systems. A central goal is to integrate single-photon detectors to reduce optical losses, latency and wiring complexity associated with off-chip detectors. Superconducting nanowire single-photon detectors (SNSPDs) are particularly attractive because of high detection efficiency, sub-50-ps jitter and nanosecond-scale reset time. However, while single detectors have been incorporated into individual waveguides, the system detection efficiency of multiple SNSPDs in one photonic circuit—required for scalable quantum photonic circuits—has been limited to <0.2%. Here we introduce a micrometer-scale flip-chip process that enables scalable integration of SNSPDs on a range of photonic circuits. Ten low-jitter detectors are integrated on one circuit with 100% device yield. With an average system detection efficiency beyond 10%, and estimated on-chip detection efficiency of 14–52% for four detectors operated simultaneously, we demonstrate, to the best of our knowledge, the first on-chip photon correlation measurements of non-classical light. PMID:25575346

  15. Dual wavelength multiple-angle light scattering system for cryptosporidium detection

    NASA Astrophysics Data System (ADS)

    Buaprathoom, S.; Pedley, S.; Sweeney, S. J.

    2012-06-01

    A simple, dual wavelength, multiple-angle, light scattering system has been developed for detecting cryptosporidium suspended in water. Cryptosporidium is a coccidial protozoan parasite causing cryptosporidiosis; a diarrheal disease of varying severity. The parasite is transmitted by ingestion of contaminated water, particularly drinking-water, but also accidental ingestion of bathing-water, including swimming pools. It is therefore important to be able to detect these parasites quickly, so that remedial action can be taken to reduce the risk of infection. The proposed system combines multiple-angle scattering detection of a single and two wavelengths, to collect relative wavelength angle-resolved scattering phase functions from tested suspension, and multivariate data analysis techniques to obtain characterizing information of samples under investigation. The system was designed to be simple, portable and inexpensive. It employs two diode lasers (violet InGaN-based and red AlGaInP-based) as light sources and silicon photodiodes as detectors and optical components, all of which are readily available. The measured scattering patterns using the dual wavelength system showed that the relative wavelength angle-resolved scattering pattern of cryptosporidium oocysts was significantly different from other particles (e.g. polystyrene latex sphere, E.coli). The single wavelength set up was applied for cryptosporidium oocysts'size and relative refractive index measurement and differential measurement of the concentration of cryptosporidium oocysts suspended in water and mixed polystyrene latex sphere suspension. The measurement results showed good agreement with the control reference values. These results indicate that the proposed method could potentially be applied to online detection in a water quality control system.

  16. Unlabeled multi tumor marker detection system based on bioinitiated light addressable potentiometric sensor.

    PubMed

    Jia, Yun-Fang; Gao, Chun-Ying; He, Jia; Feng, Dao-Fu; Xing, Ke-Li; Wu, Ming; Liu, Yang; Cai, Wen-Sheng; Feng, Xi-Zeng

    2012-08-21

    Multi biomarkers' assays are of great significance in clinical diagnosis. A label-free multi tumor markers' parallel detection system was proposed based on a light addressable potentiometric sensor (LAPS). Arrayed LAPS chips with basic structure of Si(3)N(4)-SiO(2)-Si were prepared on silicon wafers, and the label-free parallel detection system for this component was developed with user friendly controlling interfaces. Then the l-3,4-dihydroxyphenyl-alanine (L-Dopa) hydrochloric solution was used to initiate the surface of LAPS. The L-Dopa immobilization state was investigated by the theoretical calculation. L-Dopa initiated LAPS' chip was biofunctionalized respectively by the antigens and antibodies of four tumor markers, α-fetoprotein (AFP), carcinoembryonic antigen (CEA), cancer antigen 19-9 (CA19-9) and Ferritin. Then unlabeled antibodies and antigens of these four biomarkers were detected by the proposed detection systems. Furthermore physical and measuring principles in this system were described, and qualitative understanding for experimental data were given. The measured response ranges were compared with their clinical cutoff values, and sensitivities were calculated by OriginLab. The results indicate that this bioinitiated LAPS based label-free detection system may offer a new choice for the realization of unlabeled multi tumor markers' clinical assay.

  17. Refraction in Exoplanet Transit Observations

    NASA Astrophysics Data System (ADS)

    Dalba, Paul

    2018-01-01

    Before an exoplanet transit, atmospheric refraction bends light into the line of sight of an observer. The refracted light forms a stellar mirage---a distorted secondary image of the host star---that causes flux increases before transit ingress and after transit egress. The extent of this flux increase provides clues as to the composition and structure of the exoplanetary atmosphere. Here, I model the stellar mirages produced by a comprehensive set of stellar, orbital, planetary, and atmospheric parameters. Refracted light offers unprecedented atmospheric characterization opportunities for cold, long-period gas giant exoplanets. At visible wavelengths, opacity from Rayleigh scattering presents a substantial challenge to detecting stellar mirages for most exoplanets with orbital distances less than 6 AU. Based on physical parameters, I derive a criterion that determines if refracted light will significantly influence observations of a specific exoplanetary system with application to the high-precision Kepler data set. I also investigate the potential for refracted light to identify non-transiting exoplanets and serve as a novel means of out-of-transit atmospheric characterization. The atmospheric lensing events produced by non-transiting exoplanets are more detectable than the corresponding flux increases for transiting exoplanets. Compared to visible light observations, those at red to near-infrared wavelengths are more likely to detect refracted light in an exoplanet atmosphere. With upcoming exoplanet discovery and characterization missions in mind, I consider science cases that are uniquely enabled by photometric and spectroscopic observations of refracted light in exoplanetary systems.

  18. Road Lane Detection Robust to Shadows Based on a Fuzzy System Using a Visible Light Camera Sensor.

    PubMed

    Hoang, Toan Minh; Baek, Na Rae; Cho, Se Woon; Kim, Ki Wan; Park, Kang Ryoung

    2017-10-28

    Recently, autonomous vehicles, particularly self-driving cars, have received significant attention owing to rapid advancements in sensor and computation technologies. In addition to traffic sign recognition, road lane detection is one of the most important factors used in lane departure warning systems and autonomous vehicles for maintaining the safety of semi-autonomous and fully autonomous systems. Unlike traffic signs, road lanes are easily damaged by both internal and external factors such as road quality, occlusion (traffic on the road), weather conditions, and illumination (shadows from objects such as cars, trees, and buildings). Obtaining clear road lane markings for recognition processing is a difficult challenge. Therefore, we propose a method to overcome various illumination problems, particularly severe shadows, by using fuzzy system and line segment detector algorithms to obtain better results for detecting road lanes by a visible light camera sensor. Experimental results from three open databases, Caltech dataset, Santiago Lanes dataset (SLD), and Road Marking dataset, showed that our method outperformed conventional lane detection methods.

  19. First analysis of eight Algol-type binaries: EI Aur, XY Dra, BP Dra, DD Her, VX Lac, WX Lib, RZ Lyn, and TY Tri

    NASA Astrophysics Data System (ADS)

    Zasche, P.

    2016-01-01

    The available photometry from the online databases were used for the first light curve analysis of eight eclipsing binary systems EI Aur, XY Dra, BP Dra, DD Her, VX Lac, WX Lib, RZ Lyn, and TY Tri. All these stars are of Algol-type, having the detached components and the orbital periods from 0.92 to 6.8 days. For the systems EI Aur and BP Dra the large amount of the third light was detected during the light curve solution. Moreover, 468 new times of minima for these binaries were derived, trying to identify the period variations. For the systems XY Dra and VX Lac the third bodies were detected with the periods 17.7, and 49.3 years, respectively.

  20. Liquid Argon Scintillation Detection Utilizing Wavelength-Shifting Plates and Light Guides

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Howard, B.

    In DUNE, the event timing provided by the detection of the relatively prompt scintillation photons will improve spatial resolution in the drift direction of the time-projection chamber (TPC) and is especially useful for non-beam physics topics such as supernova neutrinos and nucleon decay. The baseline design for the first 10kt single phase TPC fits the photon detector system in the natural gap between the wire planes of adjacent TPC volumes. A prototype photon detector design utilizes wavelength-shifter coated plates to convert the vacuum ultraviolet scintillation light to the optical and commercially-produced wavelength-shifting light guides to trap some of this lightmore » and transport it to an array of silicon photomultipliers at the end. This system and the testing performed to characterize the system and determine the efficiency are discussed.« less

  1. SETI via Leakage from Light Sails in Exoplanetary Systems

    NASA Astrophysics Data System (ADS)

    Guillochon, James; Loeb, Abraham

    2015-10-01

    The primary challenge of rocket propulsion is the burden of needing to accelerate the spacecraft’s own fuel, resulting in only a logarithmic gain in maximum speed as propellant is added to the spacecraft. Light sails offer an attractive alternative in which fuel is not carried by the spacecraft, with acceleration being provided by an external source of light. By artificially illuminating the spacecraft with beamed radiation, speeds are only limited by the area of the sail, heat resistance of its material, and power use of the accelerating apparatus. In this paper, we show that leakage from a light sail propulsion apparatus in operation around a solar system analogue would be detectable. To demonstrate this, we model the launch and arrival of a microwave beam-driven light sail constructed for transit between planets in orbit around a single star, and find an optimal beam frequency on the order of tens of GHz. Leakage from these beams yields transients with flux densities of Jy and durations of tens of seconds at 100 pc. Because most travel within a planetary system would be conducted between the habitable worlds within that system, multiply transiting exoplanetary systems offer the greatest chance of detection, especially when the planets are in projected conjunction as viewed from Earth. If interplanetary travel via beam-driven light sails is commonly employed in our galaxy, this activity could be revealed by radio follow-up of nearby transiting exoplanetary systems. The expected signal properties define a new strategy in the search for extraterrestrial intelligence (SETI).

  2. Design and measurement technique of surface-enhanced Raman scattering for detection of bisphenol A

    NASA Astrophysics Data System (ADS)

    Abu Bakar, Norhayati; Mat Salleh, Muhamad; Umar, Akrajas Ali; Shapter, Joseph George

    2017-06-01

    Surface-enhanced Raman scattering (SERS) is a highly sensitive measurement technique that provides Raman peaks at different Raman shift for different molecule structures. The SERS sensor is potentially used to detect food contamination and monitor environmental pollutants. A self-developed SERS system for specific analysis with low development cost is a challenging issue. This study attempts to develop a simple SERS sensor system for detection of bisphenol A (BPA) molecule using SERS substrate of silver nanoplate film. A SERS sensor system was developed, consisting of a light source to excite analyte molecules, Inphotonic Raman probe, sensor chamber and spectrophotometer as an analyser system. A duplex fibre optic is used to transmit light from the source to the probe and from the probe to the spectrophotometer. For SERS measurement, BPA detection was done by comparing the Raman signal spectra of the BPA on the quartz substrate and BPA on the silver nanoplate film. This SERS sensor successfully sensed BPA with SERS enhancement factor (EF) 5.55  ×  103 and a detection limit of BPA concentration at 1 mM.

  3. Implementing and testing a fiber-optic polarization-based intrusion detection system

    NASA Astrophysics Data System (ADS)

    Hajj, Rasha El; MacDonald, Gregory; Verma, Pramode; Huck, Robert

    2015-09-01

    We describe a layer-1-based intrusion detection system for fiber-optic-based networks. Layer-1-based intrusion detection represents a significant elevation in security as it prohibits an adversary from obtaining information in the first place (no cryptanalysis is possible). We describe the experimental setup of the intrusion detection system, which is based on monitoring the behavior of certain attributes of light both in unperturbed and perturbed optical fiber links. The system was tested with optical fiber links of various lengths and types, under different environmental conditions, and under changes in fiber geometry similar to what is experienced during tapping activity. Comparison of the results for perturbed and unperturbed links has shown that the state of polarization is more sensitive to intrusion activity than the degree of polarization or power of the received light. The testing was conducted in a simulated telecommunication network environment that included both underground and aerial links. The links were monitored for intrusion activity. Attempts to tap the link were easily detected with no apparent degradation in the visual quality of the real-time surveillance video.

  4. Optimization of a Light Collection System for use in the Neutron Lifetime Project

    NASA Astrophysics Data System (ADS)

    Taylor, C.; O'Shaughnessy, C.; Mumm, P.; Thompson, A.; Huffman, P.

    2007-10-01

    The Ultracold Neutron (UCN) Lifetime Project is an ongoing experiment with the objective of improving the average measurement of the neutron beta-decay lifetime. A more accurate measurement may increase our understanding of the electroweak interaction and improve astrophysical/cosmological theories on Big Bang nucleosynthesis. The current apparatus uses 0.89 nm cold neutrons to produce UCN through inelastic collisions with superfluid 4He in the superthermal process. The lifetime of the UCN is measured by detection of scintillation light from superfluid 4He created by electrons produced in neutron decay. Competing criteria of high detection efficiency outside of the apparatus and minimum heating of the experimental cell has led to the design of an acrylic light collection system. Initial designs were based on previous generations of the apparatus. ANSYS was used to optimize the cooling system for the light guide by checking simulated end conditions based on width of contact area, number of contact points, and location on the guide itself. SolidWorks and AutoCAD were used for design. The current system is in the production process.

  5. Evaluation of a near-infrared-type contrast medium extravasation detection system using a swine model.

    PubMed

    Ishihara, Toshihiro; Kobayashi, Tatsushi; Ikeno, Naoya; Hayashi, Takayuki; Sakakibara, Masahiro; Niki, Noboru; Satake, Mitsuo; Moriyama, Noriyuki

    2014-01-01

    To refine the development and evaluate the near-infrared (NIR) extravasation detection system and its ability to detect extravasation during a contrast-enhanced computed tomography (CT) examination. The NIR extravasation detection system projects the NIR light through the surface of the human skin then, using its sensory system, will monitor the changes in the amount of NIR that reflected, which varies based on absorption properties.Seven female pigs were used to evaluate the contrast media extravasation detection system, using a 20-gauge intravenous catheter, when injected at a rate of 1 mL/s into 4 different locations just under the skin in the thigh section. Using 3-dimensional CT images, we evaluated the extravasations between time and volume, depth and volume, and finally depth and time to detect. We confirmed that the NIR light, 950-nm wavelength, used by the extravasation detection system is well absorbed by contrast media, making changes easy to detect. The average time to detect an extravasation was 2.05 seconds at a depth of 2.0 mm below the skin with a volume of 1.3 mL, 2.57 seconds at a depth between 2.1 and 5 mm below the skin and a volume of 3.47 mL, 10.5 seconds for depths greater than 5.1 mm and a volume of 11.1 mL. The detection accuracy was significantly deteriorated when the depth exceeded 5.0 mm (Tukey-Kramer, P < 0.05) CONCLUSIONS: The extravasation system detection system that is using NIR has a high level of detection sensitivity. The sensitivity enables the system to detect extravasation at depths less than 2 mm with a volume of 1.5 mL and at depths less than 5 mm with a volume of 3.5 mL. The extravasation detection system could be suitable for use during examinations.

  6. Image processing occupancy sensor

    DOEpatents

    Brackney, Larry J.

    2016-09-27

    A system and method of detecting occupants in a building automation system environment using image based occupancy detection and position determinations. In one example, the system includes an image processing occupancy sensor that detects the number and position of occupants within a space that has controllable building elements such as lighting and ventilation diffusers. Based on the position and location of the occupants, the system can finely control the elements to optimize conditions for the occupants, optimize energy usage, among other advantages.

  7. Integrated three-dimensional optical MEMS for chip-based fluorescence detection

    NASA Astrophysics Data System (ADS)

    Hung, Kuo-Yung; Tseng, Fan-Gang; Khoo, Hwa-Seng

    2009-04-01

    This paper presents a novel fluorescence sensing chip for parallel protein microarray detection in the context of a 3-in-1 protein chip system. This portable microchip consists of a monolithic integration of CMOS-based avalanche photo diodes (APDs) combined with a polymer micro-lens, a set of three-dimensional (3D) inclined mirrors for separating adjacent light signals and a low-noise transformer-free dc-dc boost mini-circuit to power the APDs (ripple below 1.28 mV, 0-5 V input, 142 V and 12 mA output). We fabricated our APDs using the planar CMOS process so as to facilitate the post-CMOS integration of optical MEMS components such as the lenses. The APD arrays were arranged in unique circular patterns appropriate for detecting the specific fluorescently labelled protein spots in our study. The array-type APDs were designed so as to compensate for any alignment error as detected by a positional error signal algorithm. The condenser lens was used as a structure for light collection to enhance the fluorescent signals by about 25%. This element also helped to reduce the light loss due to surface absorption. We fabricated an inclined mirror to separate two adjacent fluorescent signals from different specimens. Excitation using evanescent waves helped reduce the interference of the excitation light source. This approach also reduced the number of required optical lenses and minimized the complexity of the structural design. We achieved detection floors for anti-rabbit IgG and Cy5 fluorescent dye as low as 0.5 ng/µl (~3.268 nM). We argue that the intrinsic nature of point-to-point and batch-detection methods as showcased in our chip offers advantages over the serial-scanning approach used in traditional scanner systems. In addition, our system is low cost and lightweight.

  8. First step toward translation of thermophotonic lock-in imaging to dentistry as an early caries detection technology

    NASA Astrophysics Data System (ADS)

    Ojaghi, Ashkan; Parkhimchyk, Artur; Tabatabaei, Nima

    2016-09-01

    Early detection of the most prevalent oral disease worldwide, i.e., dental caries, still remains as one of the major challenges in dentistry. The current dental standard of care relies on caries detection methods, such as visual inspection and x-ray radiography, which lack the sufficient specificity and sensitivity to detect caries at early stages of formation when they can be healed. We report on the feasibility of early caries detection in a clinically and commercially viable thermophotonic imaging system. The system incorporates intensity-modulated laser light along with a low-cost long-wavelength infrared (LWIR; 8 to 14 μm) camera, providing diagnostic contrast based on the enhanced light absorption of early caries. The LWIR camera is highly suitable for integration into clinical platforms because of its low weight and cost. In addition, through theoretical modeling, we show that LWIR detection enhances the diagnostic contrast due to the minimal LWIR transmittance of enamel and suppression of the masking effect of the direct thermal Planck emission. Diagnostic performance of the system and its detection threshold are experimentally evaluated by monitoring the inception and progression of artificially induced occlusal and smooth surface caries. The results are suggestive of the suitability of the developed LWIR system for detecting early dental caries.

  9. Turbomachine monitoring system and method

    DOEpatents

    Delvaux, John McConnell

    2016-02-23

    In an embodiment, a system includes a turbomachine having a first turbomachine component including a first mechanoluminescent material. The first turbomachine component is configured to produce a first light emission upon exposure to a mechanical stimulus sufficient to cause mechanoluminescence by the first mechanoluminescent material. The system also includes a turbomachine monitoring system configured to monitor the structural health of the first component based on detection of the first light emission.

  10. System and Method of Locating Lightning Strikes

    NASA Technical Reports Server (NTRS)

    Medelius, Pedro J. (Inventor); Starr, Stanley O. (Inventor)

    2002-01-01

    A system and method of determining locations of lightning strikes has been described. The system includes multiple receivers located around an area of interest, such as a space center or airport. Each receiver monitors both sound and electric fields. The detection of an electric field pulse and a sound wave are used to calculate an area around each receiver in which the lighting is detected. A processor is coupled to the receivers to accurately determine the location of the lighting strike. The processor can manipulate the receiver data to compensate for environmental variables such as wind, temperature, and humidity. Further, each receiver processor can discriminate between distant and local lightning strikes.

  11. Systems and methods of detecting force and stress using tetrapod nanocrystal

    DOEpatents

    Choi, Charina L.; Koski, Kristie J.; Sivasankar, Sanjeevi; Alivisatos, A. Paul

    2013-08-20

    Systems and methods of detecting force on the nanoscale including methods for detecting force using a tetrapod nanocrystal by exposing the tetrapod nanocrystal to light, which produces a luminescent response by the tetrapod nanocrystal. The method continues with detecting a difference in the luminescent response by the tetrapod nanocrystal relative to a base luminescent response that indicates a force between a first and second medium or stresses or strains experienced within a material. Such systems and methods find use with biological systems to measure forces in biological events or interactions.

  12. Elastic light single-scattering spectroscopy for detection of dysplastic tissues

    NASA Astrophysics Data System (ADS)

    Canpolat, Murat; Denkçeken, Tuba; Akman, Ayşe.; Alpsoy, Erkan; Tuncer, Recai; Akyüz, Mahmut; Baykara, Mehmet; Yücel, Selçuk; Başsorgun, Ibrahim; ćiftçioǧlu, M. Akif; Gökhan, Güzide Ayşe.; Gürer, ElifInanç; Peştereli, Elif; Karaveli, Šeyda

    2013-11-01

    Elastic light single-scattering spectroscopy (ELSSS) system has been developed and tested in diagnosis of cancerous tissues of different organs. ELSSS system consists of a miniature visible light spectrometer, a single fiber optical probe, a halogen tungsten light source and a laptop. Measurements were performed on excised brain, skin, cervix and prostate tumor specimens and surrounding normal tissues. Single fiber optical probe with a core diameter of 100 μm was used to deliver white light to and from tissue. Single optical fiber probe mostly detects singly scattered light from tissue rather than diffused light. Therefore, measured spectra are sensitive to size of scatters in tissue such as cells, nuclei, mitochondria and other organelles of cells. Usually, nuclei of tumor cells are larger than nuclei of normal cells. Therefore, spectrum of singly scattered light of tumor tissue is different than normal tissue. The spectral slopes were shown to be positive for normal brain, skin and prostate and cervix tissues and negative for the tumors of the same tissues. Signs of the spectral slopes were used as a discrimination parameter to differentiate tumor from normal tissues for the three organ tissues. Sensitivity and specificity of the system in differentiation between tumors from normal tissues were 93% and %100 for brain, 87% and 85% for skin, 93.7% and 46.1% for cervix and 98% and 100% for prostate.

  13. Defect mapping system

    DOEpatents

    Sopori, Bhushan L.

    1995-01-01

    Apparatus for detecting and mapping defects in the surfaces of polycrystalline materials in a manner that distinguishes dislocation pits from grain boundaries includes a laser for illuminating a wide spot on the surface of the material, a light integrating sphere with apertures for capturing light scattered by etched dislocation pits in an intermediate range away from specular reflection while allowing light scattered by etched grain boundaries in a near range from specular reflection to pass through, and optical detection devices for detecting and measuring intensities of the respective intermediate scattered light and near specular scattered light. A center blocking aperture or filter can be used to screen out specular reflected light, which would be reflected by nondefect portions of the polycrystalline material surface. An X-Y translation stage for mounting the polycrystalline material and signal processing and computer equipment accommodate rastor mapping, recording, and displaying of respective dislocation and grain boundary defect densities. A special etch procedure is included, which prepares the polycrystalline material surface to produce distinguishable intermediate and near specular light scattering in patterns that have statistical relevance to the dislocation and grain boundary defect densities.

  14. Defect mapping system

    DOEpatents

    Sopori, B.L.

    1995-04-11

    Apparatus for detecting and mapping defects in the surfaces of polycrystalline materials in a manner that distinguishes dislocation pits from grain boundaries includes a laser for illuminating a wide spot on the surface of the material, a light integrating sphere with apertures for capturing light scattered by etched dislocation pits in an intermediate range away from specular reflection while allowing light scattered by etched grain boundaries in a near range from specular reflection to pass through, and optical detection devices for detecting and measuring intensities of the respective intermediate scattered light and near specular scattered light. A center blocking aperture or filter can be used to screen out specular reflected light, which would be reflected by nondefect portions of the polycrystalline material surface. An X-Y translation stage for mounting the polycrystalline material and signal processing and computer equipment accommodate rastor mapping, recording, and displaying of respective dislocation and grain boundary defect densities. A special etch procedure is included, which prepares the polycrystalline material surface to produce distinguishable intermediate and near specular light scattering in patterns that have statistical relevance to the dislocation and grain boundary defect densities. 20 figures.

  15. A simple and low-cost biofilm quantification method using LED and CMOS image sensor.

    PubMed

    Kwak, Yeon Hwa; Lee, Junhee; Lee, Junghoon; Kwak, Soo Hwan; Oh, Sangwoo; Paek, Se-Hwan; Ha, Un-Hwan; Seo, Sungkyu

    2014-12-01

    A novel biofilm detection platform, which consists of a cost-effective red, green, and blue light-emitting diode (RGB LED) as a light source and a lens-free CMOS image sensor as a detector, is designed. This system can measure the diffraction patterns of cells from their shadow images, and gather light absorbance information according to the concentration of biofilms through a simple image processing procedure. Compared to a bulky and expensive commercial spectrophotometer, this platform can provide accurate and reproducible biofilm concentration detection and is simple, compact, and inexpensive. Biofilms originating from various bacterial strains, including Pseudomonas aeruginosa (P. aeruginosa), were tested to demonstrate the efficacy of this new biofilm detection approach. The results were compared with the results obtained from a commercial spectrophotometer. To utilize a cost-effective light source (i.e., an LED) for biofilm detection, the illumination conditions were optimized. For accurate and reproducible biofilm detection, a simple, custom-coded image processing algorithm was developed and applied to a five-megapixel CMOS image sensor, which is a cost-effective detector. The concentration of biofilms formed by P. aeruginosa was detected and quantified by varying the indole concentration, and the results were compared with the results obtained from a commercial spectrophotometer. The correlation value of the results from those two systems was 0.981 (N = 9, P < 0.01) and the coefficients of variation (CVs) were approximately threefold lower at the CMOS image-sensor platform. Copyright © 2014 Elsevier B.V. All rights reserved.

  16. Apparatus and method using a holographic optical element for converting a spectral distribution to image points

    NASA Technical Reports Server (NTRS)

    McGill, Matthew J. (Inventor); Scott, Vibart S. (Inventor); Marzouk, Marzouk (Inventor)

    2001-01-01

    A holographic optical element transforms a spectral distribution of light to image points. The element comprises areas, each of which acts as a separate lens to image the light incident in its area to an image point. Each area contains the recorded hologram of a point source object. The image points can be made to lie in a line in the same focal plane so as to align with a linear array detector. A version of the element has been developed that has concentric equal areas to match the circular fringe pattern of a Fabry-Perot interferometer. The element has high transmission efficiency, and when coupled with high quantum efficiency solid state detectors, provides an efficient photon-collecting detection system. The element may be used as part of the detection system in a direct detection Doppler lidar system or multiple field of view lidar system.

  17. Methods and systems for detection of ice formation on surfaces

    NASA Technical Reports Server (NTRS)

    Alfano, Robert R. (Inventor); Wang, Wubao (Inventor); Sztul, Henry (Inventor); Budansky, Yury (Inventor)

    2007-01-01

    A system for detecting ice formation on metal, painted metal and other material surfaces can include a transparent window having an exterior surface upon which ice can form; a light source and optics configured and arranged to illuminate the exterior surface of the window from behind the exterior surface; and a detector and optics configured and arranged to receive light backscattered by the exterior surface and any ice disposed on the exterior surface and determine the thickness of the ice layer. For example, the system can be used with aircraft by placing one or more windows in the wings of the aircraft. The system is used for a novel optical method for real-time on-board detection and warning of ice formation on surfaces of airplanes, unmanned aerial vehicles (UAVs), and other vehicles and stationary structures to improve their safety and operation.

  18. Feasibility evaluation of a motion detection system with face images for stereotactic radiosurgery.

    PubMed

    Yamakawa, Takuya; Ogawa, Koichi; Iyatomi, Hitoshi; Kunieda, Etsuo

    2011-01-01

    In stereotactic radiosurgery we can irradiate a targeted volume precisely with a narrow high-energy x-ray beam, and thus the motion of a targeted area may cause side effects to normal organs. This paper describes our motion detection system with three USB cameras. To reduce the effect of change in illuminance in a tracking area we used an infrared light and USB cameras that were sensitive to the infrared light. The motion detection of a patient was performed by tracking his/her ears and nose with three USB cameras, where pattern matching between a predefined template image for each view and acquired images was done by an exhaustive search method with a general-purpose computing on a graphics processing unit (GPGPU). The results of the experiments showed that the measurement accuracy of our system was less than 0.7 mm, amounting to less than half of that of our previous system.

  19. A Sensor System for Detection of Hull Surface Defects

    PubMed Central

    Navarro, Pedro; Iborra, Andrés; Fernández, Carlos; Sánchez, Pedro; Suardíaz, Juan

    2010-01-01

    This paper presents a sensor system for detecting defects in ship hull surfaces. The sensor was developed to enable a robotic system to perform grit blasting operations on ship hulls. To achieve this, the proposed sensor system captures images with the help of a camera and processes them in real time using a new defect detection method based on thresholding techniques. What makes this method different is its efficiency in the automatic detection of defects from images recorded in variable lighting conditions. The sensor system was tested under real conditions at a Spanish shipyard, with excellent results. PMID:22163590

  20. Real-time defect detection on highly reflective curved surfaces

    NASA Astrophysics Data System (ADS)

    Rosati, G.; Boschetti, G.; Biondi, A.; Rossi, A.

    2009-03-01

    This paper presents an automated defect detection system for coated plastic components for the automotive industry. This research activity came up as an evolution of a previous study which employed a non-flat mirror to illuminate and inspect high reflective curved surfaces. According to this method, the rays emitted from a light source are conveyed on the surface under investigation by means of a suitably curved mirror. After the reflection on the surface, the light rays are collected by a CCD camera, in which the coating defects appear as shadows of various shapes and dimensions. In this paper we present an evolution of the above-mentioned method, introducing a simplified mirror set-up in order to reduce the costs and the complexity of the defect detection system. In fact, a set of plane mirrors is employed instead of the curved one. Moreover, the inspection of multiple bend radius parts is investigated. A prototype of the machine vision system has been developed in order to test this simplified method. This device is made up of a light projector, a set of plane mirrors for light rays reflection, a conveyor belt for handling components, a CCD camera and a desktop PC which performs image acquisition and processing. Like in the previous system, the defects are identified as shadows inside a high brightness image. At the end of the paper, first experimental results are presented.

  1. The research of knitting needle status monitoring setup

    NASA Astrophysics Data System (ADS)

    Liu, Lu; Liao, Xiao-qing; Zhu, Yong-kang; Yang, Wei; Zhang, Pei; Zhao, Yong-kai; Huang, Hui-jie

    2013-09-01

    In textile production, quality control and testing is the key to ensure the process and improve the efficiency. Defect of the knitting needles is the main factor affecting the quality of the appearance of textiles. Defect detection method based on machine vision and image processing technology is universal. This approach does not effectively identify the defect generated by damaged knitting needles and raise the alarm. We developed a knitting needle status monitoring setup using optical imaging, photoelectric detection and weak signal processing technology to achieve real-time monitoring of weaving needles' position. Depending on the shape of the knitting needle, we designed a kind of Glass Optical Fiber (GOF) light guides with a rectangular port used for transmission of the signal light. To be able to capture the signal of knitting needles accurately, we adopt a optical 4F system which has better imaging quality and simple structure and there is a rectangle image on the focal plane after the system. When a knitting needle passes through position of the rectangle image, the reflected light from needle surface will back to the GOF light guides along the same optical system. According to the intensity of signals, the computer control unit distinguish that the knitting needle is broken or curving. The experimental results show that this system can accurately detect the broken needles and the curving needles on the knitting machine in operating condition.

  2. Method and system for evaluating integrity of adherence of a conductor bond to a mating surface of a substrate

    DOEpatents

    Telschow, K.L.; Siu, B.K.

    1996-07-09

    A method of evaluating integrity of adherence of a conductor bond to a substrate includes: (a) impinging a plurality of light sources onto a substrate; (b) detecting optical reflective signatures emanating from the substrate from the impinged light; (c) determining location of a selected conductor bond on the substrate from the detected reflective signatures; (d) determining a target site on the selected conductor bond from the detected reflective signatures; (e) optically imparting an elastic wave at the target site through the selected conductor bond and into the substrate; (f) optically detecting an elastic wave signature emanating from the substrate resulting from the optically imparting step; and (g) determining integrity of adherence of the selected conductor bond to the substrate from the detected elastic wave signature emanating from the substrate. A system is disclosed which is capable of conducting the method. 13 figs.

  3. Method and system for evaluating integrity of adherence of a conductor bond to a mating surface of a substrate

    DOEpatents

    Telschow, Kenneth L.; Siu, Bernard K.

    1996-01-01

    A method of evaluating integrity of adherence of a conductor bond to a substrate includes: a) impinging a plurality of light sources onto a substrate; b) detecting optical reflective signatures emanating from the substrate from the impinged light; c) determining location of a selected conductor bond on the substrate from the detected reflective signatures; d) determining a target site on the selected conductor bond from the detected reflective signatures; e) optically imparting an elastic wave at the target site through the selected conductor bond and into the substrate; f) optically detecting an elastic wave signature emanating from the substrate resulting from the optically imparting step; and g) determining integrity of adherence of the selected conductor bond to the substrate from the detected elastic wave signature emanating from the substrate. A system is disclosed which is capable of conducting the method.

  4. "Smoke": Characterization Of Smoke Particulate For Spacecraft Fire Detection

    NASA Technical Reports Server (NTRS)

    Urban, David L.; Mulholland, George W.; Yang, Jiann; Cleary, Thomas G.; Yuan, Zeng-Guang

    2003-01-01

    The "Smoke" experiment is a flight definition investigation that seeks to increase our understanding of spacecraft fire detection through measurements of particulate size distributions of preignition smokes from typical spacecraft materials. Owing to the catastrophic risk posed by even a very small fire in a spacecraft, the design goal for spacecraft fire detection is to detect the fire as quickly as possible, preferably in the preignition phase before a real flaming fire has developed. Consequently the target smoke for detection is typically not soot (typical of established hydrocarbon fires) but instead, pyrolysis products, and recondensed polymer particles. At the same time, false alarms are extremely costly as the crew and the ground team must respond quickly to every alarm. The U.S. Space Shuttle (STS: Space Transportation System) and the International Space Station (ISS) both use smoke detection as the primary means of fire detection. These two systems were designed in the absence of any data concerning low-gravity smoke particle (and background dust) size distributions. The STS system uses an ionization detector coupled with a sampling pump and the ISS system is a forward light scattering detector operating in the near IR. These two systems have significantly different sensitivities with the ionization detector being most sensitive (on a mass concentration basis) to smaller particulate and the light scattering detector being most sensitive to particulate that is larger than 1 micron. Since any smoke detection system has inherent size sensitivity characteristics, proper design of future smoke detection systems will require an understanding of the background and alarm particle size distributions that can be expected in a space environment.

  5. Low-Cost Charged-Coupled Device (CCD) Based Detectors for Shiga Toxins Activity Analysis.

    PubMed

    Rasooly, Reuven; Prickril, Ben; Bruck, Hugh A; Rasooly, Avraham

    2017-01-01

    To improve food safety there is a need to develop simple, low-cost sensitive devices for detection of food-borne pathogens and their toxins. We describe a simple, low-cost webcam-based detector which can be used for various optical detection modalities, including fluorescence, chemiluminescence, densitometry, and colorimetric assays. The portable battery-operated CCD-based detection system consists of four modules: (1) a webcam to measure and record light emission, (2) a sample plate to perform assays, (3) a light emitting diode (LED) for illumination, and (4) a portable computer to acquire and analyze images. To demonstrate the technology, we used a cell based assay for fluorescence detection of the activity of the food borne Shiga toxin type 2 (Stx2), differentiating between biologically active toxin and inactive toxin which is not a risk. The assay is based on Shiga toxin inhibition of cell protein synthesis measured through inhibition of the green fluorescent protein (GFP). In this assay, GFP emits light at 509 nm when excited with a blue LED equipped with a filter at 486 nm. The emitted light is then detected with a green filter at 535 nm. Toxin activity is measured through a reduction in the 509 nm emission. In this system the level of detection (LOD) for Stx2 was 0.1 pg/ml, similar to the LOD of commercial fluorometers. These results demonstrate the utility and potential of low cost detectors for toxin activity. This approach could be readily adapted to the detection of other food-borne toxins.

  6. 40 CFR 63.163 - Standards: Pumps in light liquid service.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) Equipped with a barrier fluid degassing reservoir that is routed to a process or fuel gas system or... with a sensor that will detect failure of the seal system, the barrier fluid system, or both. (4) Each... per million or greater is measured, a leak is detected. (5) Each sensor as described in paragraph (e...

  7. Effect of light intensity on food detection in captive great fruit-eating bats, Artibeus lituratus (Chiroptera: Phyllostomidae).

    PubMed

    Gutierrez, Eduardo de A; Pessoa, Valdir F; Aguiar, Ludmilla M S; Pessoa, Daniel M A

    2014-11-01

    Bats are known for their well-developed echolocation. However, several experiments focused on the bat visual system have shown evidence of the importance of visual cues under specific luminosity for different aspects of bat biology, including foraging behavior. This study examined the foraging abilities of five female great fruit-eating bats, Artibeus lituratus, under different light intensities. Animals were given a series of tasks to test for discrimination between a food target against an inedible background, under light levels similar to the twilight illumination (18lx), the full moon (2lx) and complete darkness (0lx). We found that the bats required a longer time frame to detect targets under a light intensity similar to twilight, possibly due to inhibitory effects present under a more intense light level. Additionally, bats were more efficient at detecting and capturing targets under light conditions similar to the luminosity of a full moon, suggesting that visual cues were important for target discrimination. These results demonstrate that light intensity affects foraging behavior and enables the use of visual cues for food detection in frugivorous bats. This article is part of a Special Issue entitled: Neotropical Behaviour. Copyright © 2014 Elsevier B.V. All rights reserved.

  8. Recent advances in near-infrared fluorescence-guided imaging surgery using indocyanine green.

    PubMed

    Namikawa, Tsutomu; Sato, Takayuki; Hanazaki, Kazuhiro

    2015-12-01

    Near-infrared (NIR) fluorescence imaging has better tissue penetration, allowing for the effective rejection of excitation light and detection deep inside organs. Indocyanine green (ICG) generates NIR fluorescence after illumination by an NIR ray, enabling real-time intraoperative visualization of superficial lymphatic channels and vessels transcutaneously. The HyperEye Medical System (HEMS) can simultaneously detect NIR rays under room light to provide color imaging, which enables visualization under bright light. Thus, NIR fluorescence imaging using ICG can provide for excellent diagnostic accuracy in detecting sentinel lymph nodes in cancer and microvascular circulation in various ischemic diseases, to assist us with intraoperative decision making. Including HEMS in this system could further improve the sentinel lymph node mapping and intraoperative identification of blood supply in reconstructive organs and ischemic diseases, making it more attractive than conventional imaging. Moreover, the development of new laparoscopic imaging systems equipped with NIR will allow fluorescence-guided surgery in a minimally invasive setting. Future directions, including the conjugation of NIR fluorophores to target specific cancer markers might be realistic technology with diagnostic and therapeutic benefits.

  9. Electronic method for autofluorography of macromolecules on two-D matrices. [Patent application

    DOEpatents

    Davidson, J.B.; Case, A.L.

    1981-12-30

    A method for detecting, localizing, and quantifying macromolecules contained in a two-dimensional matrix is provided which employs a television-based position sensitive detection system. A molecule-containing matrix may be produced by conventional means to produce spots of light at the molecule locations which are detected by the television system. The matrix, such as a gel matrix, is exposed to an electronic camera system including an image-intensifier and secondary electron conduction camera capable of light integrating times of many minutes. A light image stored in the form of a charge image on the camera tube target is scanned by conventional television techniques, digitized, and stored in a digital memory. Intensity of any point on the image may be determined from the number at the memory address of the point. The entire image may be displayed on a television monitor for inspection and photographing or individual spots may be analyzed through selected readout of the memory locations. Compared to conventional film exposure methods, the exposure time may be reduced 100 to 1000 times.

  10. Near-IR Polarized Scattered Light Imagery of the DoAr 28 Transitional Disk

    NASA Technical Reports Server (NTRS)

    Rich, Evan A.; Wisiniewski, John P.; Mayama, Satoshi; Brandt, Timothy D.; Hashimoto, Jun; Kudo, Tomoyuki; Kusakabe, Nobuhiko; Espaillat, Catherine; Serabyn, Eugene; Grady, Carol A.; hide

    2015-01-01

    We present the first spatially resolved polarized scattered light H-band detection of the DoAr 28 transitional disk. Our two epochs of imagery detect the scattered light disk from our effective inner working angle of 0 double prime.10 (13 AU) out to 0double prime.50 (65 AU). This inner working angle is interior to the location of the system's gap inferred by previous studies using spectral energy distribution modeling (15 AU). We detected a candidate point source companion 1 double prime.08 northwest of the system; however, our second epoch of imagery strongly suggests that this object is a background star. We constructed a grid of Monte Carlo Radiative Transfer models of the system, and our best fit models utilize a modestly inclined (50 degrees), 0.01 solar mass disk that has a partially depleted inner gap from the dust sublimation radius out to approximately 8 AU. Subtracting this best fit, axi-symmetric model from our polarized intensity data reveals evidence for two small asymmetries in the disk, which could be attributable to a variety of mechanisms.

  11. Laser pulse detection method and apparatus

    NASA Technical Reports Server (NTRS)

    Goss, W.; Janesick, J. R. (Inventor)

    1984-01-01

    A sensor is described for detecting the difference in phase of a pair of returned light pulse components, such as two components of a light pulse of an optical gyro. In an optic gyro, the two light components have passed in opposite directions through a coil of optical fiber, with the difference in phase of the returned light components determining the intensity of light shining on the sensor. The sensor includes a CCD (charge coupled device) that receives the pair of returned light components to generate a charge proportional to the number of photons in the received light. The amount of the charge represents the phase difference between the two light components. At a time after the transmission of the light pulse and before the expected time of arrival of the interfering light components, charge accumulating in the CCD as a result of reflections from components in the system, are repeatedly removed from the CCD, by transferring out charges in the CCD and dumping these charges.

  12. Internal-illumination photoacoustic computed tomography

    NASA Astrophysics Data System (ADS)

    Li, Mucong; Lan, Bangxin; Liu, Wei; Xia, Jun; Yao, Junjie

    2018-03-01

    We report a photoacoustic computed tomography (PACT) system using a customized optical fiber with a cylindrical diffuser to internally illuminate deep targets. The traditional external light illumination in PACT usually limits the penetration depth to a few centimeters from the tissue surface, mainly due to strong optical attenuation along the light propagation path from the outside in. By contrast, internal light illumination, with external ultrasound detection, can potentially detect much deeper targets. Different from previous internal illumination PACT implementations using forward-looking optical fibers, our internal-illumination PACT system uses a customized optical fiber with a 3-cm-long conoid needle diffuser attached to the fiber tip, which can homogeneously illuminate the surrounding space and substantially enlarge the field of view. We characterized the internal illumination distribution and PACT system performance. We performed tissue phantom and in vivo animal studies to further demonstrate the superior imaging depth using internal illumination over external illumination. We imaged a 7.5-cm-deep leaf target embedded in optically scattering medium and the beating heart of a mouse overlaid with 3.7-cm-thick chicken tissue. Our results have collectively demonstrated that the internal light illumination combined with external ultrasound detection might be a useful strategy to improve the penetration depth of PACT in imaging deep organs of large animals and humans.

  13. Under-sampling in a Multiple-Channel Laser Vibrometry System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Corey, Jordan

    2007-03-01

    Laser vibrometry is a technique used to detect vibrations on objects using the interference of coherent light with itself. Most vibrometry systems process only one target location at a time, but processing multiple locations simultaneously provides improved detection capabilities. Traditional laser vibrometry systems employ oversampling to sample the incoming modulated-light signal, however as the number of channels increases in these systems, certain issues arise such a higher computational cost, excessive heat, increased power requirements, and increased component cost. This thesis describes a novel approach to laser vibrometry that utilizes undersampling to control the undesirable issues associated with over-sampled systems. Undersamplingmore » allows for significantly less samples to represent the modulated-light signals, which offers several advantages in the overall system design. These advantages include an improvement in thermal efficiency, lower processing requirements, and a higher immunity to the relative intensity noise inherent in laser vibrometry applications. A unique feature of this implementation is the use of a parallel architecture to increase the overall system throughput. This parallelism is realized using a hierarchical multi-channel architecture based on off-the-shelf programmable logic devices (PLDs).« less

  14. Multi-channel photon counting DOT system based on digital lock-in detection technique

    NASA Astrophysics Data System (ADS)

    Wang, Tingting; Zhao, Huijuan; Wang, Zhichao; Hou, Shaohua; Gao, Feng

    2011-02-01

    Relying on deeper penetration of light in the tissue, Diffuse Optical Tomography (DOT) achieves organ-level tomography diagnosis, which can provide information on anatomical and physiological features. DOT has been widely used in imaging of breast, neonatal cerebral oxygen status and blood oxygen kinetics observed by its non-invasive, security and other advantages. Continuous wave DOT image reconstruction algorithms need the measurement of the surface distribution of the output photon flow inspired by more than one driving source, which means that source coding is necessary. The most currently used source coding in DOT is time-division multiplexing (TDM) technology, which utilizes the optical switch to switch light into optical fiber of different locations. However, in case of large amounts of the source locations or using the multi-wavelength, the measurement time with TDM and the measurement interval between different locations within the same measurement period will therefore become too long to capture the dynamic changes in real-time. In this paper, a frequency division multiplexing source coding technology is developed, which uses light sources modulated by sine waves with different frequencies incident to the imaging chamber simultaneously. Signal corresponding to an individual source is obtained from the mixed output light using digital phase-locked detection technology at the detection end. A digital lock-in detection circuit for photon counting measurement system is implemented on a FPGA development platform. A dual-channel DOT photon counting experimental system is preliminary established, including the two continuous lasers, photon counting detectors, digital lock-in detection control circuit, and codes to control the hardware and display the results. A series of experimental measurements are taken to validate the feasibility of the system. This method developed in this paper greatly accelerates the DOT system measurement, and can also obtain the multiple measurements in different source-detector locations.

  15. Out-of-transit Refracted Light in the Atmospheres of Transiting and Non-transiting Exoplanets

    NASA Astrophysics Data System (ADS)

    Dalba, Paul A.

    2017-10-01

    Before an exoplanet transit, atmospheric refraction bends light into the line of sight of an observer. The refracted light forms a stellar mirage—a distorted secondary image of the host star. I model this phenomenon and the resultant out-of-transit flux increase across a comprehensive exoplanetary parameter space. At visible wavelengths, Rayleigh scattering limits the detectability of stellar mirages in most exoplanetary systems with semimajor axes ≲ 6 {au}. A notable exception is almost any planet orbiting a late M or ultra-cool dwarf star at ≳ 0.5 {au}, where the maximum relative flux increase is >50 parts per million. Based partly on previous work, I propose that the importance of refraction in an exoplanet system is governed by two angles: the orbital distance divided by the stellar radius and the total deflection achieved by a ray in the optically thin portion of the atmosphere. Atmospheric lensing events caused by non-transiting exoplanets, which allow for exoplanet detection and atmospheric characterization, are also investigated. I derive the basic formalism to determine the total signal-to-noise ratio of an atmospheric lensing event, with application to Kepler data. It is unlikely that out-of-transit refracted light signals are clearly present in Kepler data due to Rayleigh scattering and the bias toward short-period exoplanets. However, observations at long wavelengths (e.g., the near-infrared) are significantly more likely to detect stellar mirages. Lastly, I discuss the potential for the Transiting Exoplanet Survey Satellite to detect refracted light and consider novel science cases enabled by refracted light spectra from the James Webb Space Telescope.

  16. Portable widefield imaging device for ICG-detection of the sentinel lymph node

    NASA Astrophysics Data System (ADS)

    Govone, Angelo Biasi; Gómez-García, Pablo Aurelio; Carvalho, André Lopes; Capuzzo, Renato de Castro; Magalhães, Daniel Varela; Kurachi, Cristina

    2015-06-01

    Metastasis is one of the major cancer complications, since the malignant cells detach from the primary tumor and reaches other organs or tissues. The sentinel lymph node (SLN) is the first lymphatic structure to be affected by the malignant cells, but its location is still a great challenge for the medical team. This occurs due to the fact that the lymph nodes are located between the muscle fibers, making it visualization difficult. Seeking to aid the surgeon in the detection of the SLN, the present study aims to develop a widefield fluorescence imaging device using the indocyanine green as fluorescence marker. The system is basically composed of a 780nm illumination unit, optical components for 810nm fluorescence detection, two CCD cameras, a laptop, and dedicated software. The illumination unit has 16 diode lasers. A dichroic mirror and bandpass filters select and deliver the excitation light to the interrogated tissue, and select and deliver the fluorescence light to the camera. One camera is responsible for the acquisition of visible light and the other one for the acquisition of the ICG fluorescence. The software developed at the LabVIEW® platform generates a real time merged image where it is possible to observe the fluorescence spots, related to the lymph nodes, superimposed at the image under white light. The system was tested in a mice model, and a first patient with tongue cancer was imaged. Both results showed the potential use of the presented fluorescence imaging system assembled for sentinel lymph node detection.

  17. Flame Imaging System

    NASA Technical Reports Server (NTRS)

    Barnes, Heidi L. (Inventor); Smith, Harvey S. (Inventor)

    1998-01-01

    A system for imaging a flame and the background scene is discussed. The flame imaging system consists of two charge-coupled-device (CCD) cameras. One camera uses a 800 nm long pass filter which during overcast conditions blocks sufficient background light so the hydrogen flame is brighter than the background light, and the second CCD camera uses a 1100 nm long pass filter, which blocks the solar background in full sunshine conditions such that the hydrogen flame is brighter than the solar background. Two electronic viewfinders convert the signal from the cameras into a visible image. The operator can select the appropriate filtered camera to use depending on the current light conditions. In addition, a narrow band pass filtered InGaAs sensor at 1360 nm triggers an audible alarm and a flashing LED if the sensor detects a flame, providing additional flame detection so the operator does not overlook a small flame.

  18. Tools for Observing our Universe

    NASA Technical Reports Server (NTRS)

    Wollack, Ed

    2008-01-01

    A selection of hands on demonstrations related to the detection of light will be presented to middle students. The primary emphasis of the talk will be on conveying how scientists use light to remotely observe and understand the properties of astrophysical systems.

  19. Real-time alkali monitoring system

    DOEpatents

    Goff, David R.; Romanosky, Robert R.; Hensel, Peter

    1990-01-01

    A fiber optics based optical emission line monitoring system is provided in which selected spectral emission lines, such as the sodium emission line, may be detected in the presence of interfering background radiation. A combustion flame is fed by a diverted portion of a process stream and the common end of a bifurcated or quadfurcated fiber optic light guide is adapted to collect light from the flame. The light is guided through the branches of the fiber optic cable to bandpass filters, one of which is adapted to each of the branches of the fiber optic light guide. The bandpass filters are centered at wavelengths corresponding to the emission lines to be detected and two separate filters are required for each species being detected. The first filter has a bandwidth of about 3 nms and the second filter has a bandwidth of about 10 nms. Light detectors are located to view the light passing through the bandpass filters and amplifiers are connected to receive signals from the light detectors. The amplifier corresponding to the bandpass filter having the narrower bandwidth is preset to scale the signal by a factor equal to the ratio of the wide and narrow bandwidths of the bandpass filters. This scaling produces a scaled signal from which the difference between the scaled signal on the other signal can be calculated to produce a signal having an amplitude directly proportional to the concentration of the species of interest and independent of background radiation.

  20. Long-Wave Infrared Thermophotonic Imaging of Demineralization in Dental Hard Tissue

    NASA Astrophysics Data System (ADS)

    Ojaghi, A.; Parkhimchyk, A.; Tabatabaei, N.

    2016-08-01

    Dental caries remains the most prevalent chronic disease in both children and adults worldwide. To address this prevalence through disease prevention and management, dentists need tools capable of detecting caries at early stages of formation. Looking into the physics of light propagation in teeth, this study presents a clinically and commercially viable platform technology for thermophotonic detection of early dental caries using an inexpensive long-wavelength infrared (LWIR; 8 μm to 14 μm) camera. The developed system incorporates intensity-modulated light to generate a thermal-wave field inside enamel and uses the subsequent infrared emission of the thermal-wave field to detect early caries. It was found that the greater light absorption at caries sites shifts the thermal-wave field centroid, providing contrast between early caries and intact enamel. Use of LWIR detection band in dental samples is novel and beneficial over the conventional mid-wavelength infrared band (3 μm to 5 μm) as it suppresses the masking effect of the instantaneous radiative emission from subsurface features due to the minimal transmittance of enamel in the LWIR band. The efficacy of the LWIR system is verified though experiments carried out on nonbiological test samples as well as on teeth with natural and artificially induced caries. The results suggest that the developed LWIR technology is an affordable early dental caries detection system suitable for commercialization/translation to Dentistry.

  1. Activation of Organic Photovoltaic Light Detectors Using Bend Leakage from Optical Fibers.

    PubMed

    Griffith, Matthew J; Willis, Matthew S; Kumar, Pankaj; Holdsworth, John L; Bezuidenhout, Henco; Zhou, Xiaojing; Belcher, Warwick; Dastoor, Paul C

    2016-03-01

    This work investigates the detection and subsequent utilization of leaked light from bends in a silica optical fiber using organic photovoltaic detectors. The optic power lost by single mode and multimode silica optical fibers was calibrated for bend radii between 1 and 7 mm for 532 and 633 nm light, exhibiting excellent agreement with previous theoretical solutions. The spatial location of maximum power leakage on the exterior of the fiber was found to exist in the same plane as the fiber, with a 10° offset from the normal. Two different organic photovoltaic detectors fabricated using a poly(3-hexylthiophene):indene-C60-bisadduct donor-acceptor blend cast from chloroform and chlorobenzene were fabricated to detect the leaked light. The two detectors exhibited different photovoltaic performances, predominantly due to different active layer thicknesses. Both devices showed sensitivity to leakage light, exhibiting voltages between 200 and 300 mV in response to leaked light from the fiber. The temporal responses of the devices were observed to differ, with a rise time from 10% to 90% of maximum voltage of 1430 μs for the chlorobenzene device, and a corresponding rise time of 490 μs for the higher performing chloroform device. The two OPVs were used to simultaneously detect leaked light from induced bends in the optical fiber, with the differing temporal profiles employed to create a unique time-correlated detection signal with enhanced security. The delay between detection of each OPV voltage could be systematically varied, allowing for either a programmable and secure single detection signal or triggering of multiple events with variable time resolution. The results reported in this study present exciting avenues toward the deployment of this simple and noninvasive optical detection system in a range of different applications.

  2. A lamp light-emitting diode-induced fluorescence detector for capillary electrophoresis.

    PubMed

    Xu, Jing; Xiong, Yan; Chen, Shiheng; Guan, Yafeng

    2008-07-15

    A light-emitting diode-induced fluorescence detector (LED-FD) for capillary electrophoresis was constructed and evaluated. A lamp LED with an enhanced emission spectrum and a band pass filter was used as the excitation light source. Refractive index matching fluid (RIMF) was used in the detection cell to reduce scattering light and the noise level. The limit of detection (LOD) for fluorescein was 1.5 nM (SNR=3). The system exhibited linear responses in the range of 1 x 10(-8) to 5 x 10(-6)M (R=0.999). Application of the lamp LED-FD for the analysis of FITC-labeled ephedra herb extract by capillary electrophoresis was demonstrated.

  3. THE CENTER OF LIGHT: SPECTROASTROMETRIC DETECTION OF EXOMOONS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Agol, Eric; Jansen, Tiffany; Lacy, Brianna

    2015-10-10

    Direct imaging of extrasolar planets with future space-based coronagraphic telescopes may provide a means of detecting companion moons at wavelengths where the moon outshines the planet. We propose a detection strategy based on the positional variation of the center of light with wavelength, “spectroastrometry.” This new application of this technique could be used to detect an exomoon, to determine the exomoon’s orbit and the mass of the host exoplanet, and to disentangle the spectra of the planet and moon. We consider two model systems, for which we discuss the requirements for detection of exomoons around nearby stars. We simulate themore » characterization of an Earth–Moon analog system with spectroastrometry, showing that the orbit, the planet mass, and the spectra of both bodies can be recovered. To enable the detection and characterization of exomoons we recommend that coronagraphic telescopes should extend in wavelength coverage to 3 μm, and should be designed with spectroastrometric requirements in mind.« less

  4. Shadow Detection Based on Regions of Light Sources for Object Extraction in Nighttime Video

    PubMed Central

    Lee, Gil-beom; Lee, Myeong-jin; Lee, Woo-Kyung; Park, Joo-heon; Kim, Tae-Hwan

    2017-01-01

    Intelligent video surveillance systems detect pre-configured surveillance events through background modeling, foreground and object extraction, object tracking, and event detection. Shadow regions inside video frames sometimes appear as foreground objects, interfere with ensuing processes, and finally degrade the event detection performance of the systems. Conventional studies have mostly used intensity, color, texture, and geometric information to perform shadow detection in daytime video, but these methods lack the capability of removing shadows in nighttime video. In this paper, a novel shadow detection algorithm for nighttime video is proposed; this algorithm partitions each foreground object based on the object’s vertical histogram and screens out shadow objects by validating their orientations heading toward regions of light sources. From the experimental results, it can be seen that the proposed algorithm shows more than 93.8% shadow removal and 89.9% object extraction rates for nighttime video sequences, and the algorithm outperforms conventional shadow removal algorithms designed for daytime videos. PMID:28327515

  5. SETI VIA LEAKAGE FROM LIGHT SAILS IN EXOPLANETARY SYSTEMS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Guillochon, James; Loeb, Abraham, E-mail: jguillochon@cfa.harvard.edu, E-mail: aloeb@cfa.harvard.edu

    The primary challenge of rocket propulsion is the burden of needing to accelerate the spacecraft’s own fuel, resulting in only a logarithmic gain in maximum speed as propellant is added to the spacecraft. Light sails offer an attractive alternative in which fuel is not carried by the spacecraft, with acceleration being provided by an external source of light. By artificially illuminating the spacecraft with beamed radiation, speeds are only limited by the area of the sail, heat resistance of its material, and power use of the accelerating apparatus. In this paper, we show that leakage from a light sail propulsionmore » apparatus in operation around a solar system analogue would be detectable. To demonstrate this, we model the launch and arrival of a microwave beam-driven light sail constructed for transit between planets in orbit around a single star, and find an optimal beam frequency on the order of tens of GHz. Leakage from these beams yields transients with flux densities of Jy and durations of tens of seconds at 100 pc. Because most travel within a planetary system would be conducted between the habitable worlds within that system, multiply transiting exoplanetary systems offer the greatest chance of detection, especially when the planets are in projected conjunction as viewed from Earth. If interplanetary travel via beam-driven light sails is commonly employed in our galaxy, this activity could be revealed by radio follow-up of nearby transiting exoplanetary systems. The expected signal properties define a new strategy in the search for extraterrestrial intelligence (SETI)« less

  6. Dual-foci detection in photoacoustic computed tomography with coplanar light illumination and acoustic detection: a phantom study.

    PubMed

    Lin, Xiangwei; Liu, Chengbo; Meng, Jing; Gong, Xiaojing; Lin, Riqiang; Sun, Mingjian; Song, Liang

    2018-05-01

    A dual-foci transducer with coplanar light illumination and acoustic detection was applied for the first time. It overcame the small directivity angle, low-sensitivity, and large datasets in conventional circular scanning or array-based photoacoustic computed tomography (PACT). The custom-designed transducer is focused on both the scanning plane with virtual-point detection and the elevation direction for large field of view (FOV) cross-sectional imaging. Moreover, a coplanar light illumination and acoustic detection configuration can provide ring-shaped light irradiation with highly efficient acoustic detection, which in principle has a better adaptability when imaging samples of irregular surfaces. Phantom experiments showed that our PACT system can achieve high resolution (∼0.5  mm), enhanced signal-to-noise ratio (16-dB improvement), and a more complete structure in a greater FOV with an equal number of sampling points compared with the results from a flat aperture transducer. This study provides the proof of concept for the fabrication of a sparse array with the dual-foci property and large aperture size for high-quality, low-cost, and high-speed photoacoustic imaging. (2018) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).

  7. A polarization measurement method for the quantification of retardation in optic nerve fiber layer

    NASA Astrophysics Data System (ADS)

    Fukuma, Yasufumi; Okazaki, Yoshio; Shioiri, Takashi; Iida, Yukio; Kikuta, Hisao; Ohnuma, Kazuhiko

    2008-02-01

    The thickness measurement of the optic nerve fiber layer is one of the most important evaluations for carrying out glaucoma diagnosis. Because the optic nerve fiber layer has birefringence, the thickness can be measured by illuminating eye optics with circular polarized light and analyzing the elliptical rate of the detected polarized light reflected from the optic nerve fiber layer. In this method, the scattering light from the background and the retardation caused by the cornea disturbs the precise measurement. If the Stokes vector expressing the whole state of polarization can be detected, we can eliminate numerically the influence of the background scattering and of the retardation caused by the cornea. Because the retardation process of the eye optics can be represented by a numerical equation using the retardation matrix of each component and also the nonpolarized background scattering light, it can be calculated by using the Stokes vector. We applied a polarization analysis system that can detect the Stokes vector onto the fundus camera. The polarization analysis system is constructed with a CCD area image sensor, a linear polarizing plate, a micro phase plate array, and a circularly polarized light illumination unit. With this simply constructed system, we can calculate the retardation caused only by the optic nerve fiber layer and it can predict the thickness of the optic nerve fiber layer. We report the method and the results graphically showing the retardation of the optic nerve fiber layer without the retardation of the cornea.

  8. Image-enhanced endoscopy for diagnosis of colorectal tumors in view of endoscopic treatment

    PubMed Central

    Yoshida, Naohisa; Yagi, Nobuaki; Yanagisawa, Akio; Naito, Yuji

    2012-01-01

    Recently, image-enhanced endoscopy (IEE) has been used to diagnose gastrointestinal tumors. This method is a change from conventional white-light (WL) endoscopy without dyeing solution, requiring only the push of a button. In IEE, there are many advantages in diagnosis of neoplastic tumors, evaluation of invasion depth for cancerous lesions, and detection of neoplastic lesions. In narrow band imaging (NBI) systems (Olympus Medical Co., Tokyo, Japan), optical filters that allow narrow-band light to pass at wavelengths of 415 and 540 nm are used. Mucosal surface blood vessels are seen most clearly at 415 nm, which is the wavelength that corresponds to the hemoglobin absorption band, while vessels in the deep layer of the mucosa can be detected at 540 nm. Thus, NBI also can detect pit-like structures named surface pattern. The flexible spectral imaging color enhancement (FICE) system (Fujifilm Medical Co., Tokyo, Japan) is also an IEE but different to NBI. FICE depends on the use of spectral-estimation technology to reconstruct images at different wavelengths based on WL images. FICE can enhance vascular and surface patterns. The autofluorescence imaging (AFI) video endoscope system (Olympus Medical Co., Tokyo, Japan) is a new illumination method that uses the difference in intensity of autofluorescence between the normal area and neoplastic lesions. AFI light comprises a blue light for emitting and a green light for hemoglobin absorption. The aim of this review is to highlight the efficacy of IEE for diagnosis of colorectal tumors for endoscopic treatment. PMID:23293724

  9. Development of new devices for detection of gastric cancer on laparoscopic surgery using near-infrared light

    NASA Astrophysics Data System (ADS)

    Inada, Shunko A.; Fuchi, Shingo; Mori, Kensaku; Hasegawa, Junichi; Misawa, Kazunari; Nakanishi, Hayao

    2015-03-01

    In recent year, for the treatment of gastric cancer the laparoscopic surgery is performed, which has good benefits, such as low-burden, low-invasive and the efficacy is equivalent to the open surgery. For identify location of the tumor intraperitoneally for extirpation of the gastric cancer, several points of charcoal ink is injected around the primary tumor. However, in the time of laparoscopic operation, it is difficult to estimate specific site of primary tumor, because the injected charcoal ink diffusely spread to the area distant from the tumor in the stomach. Therefore, a broad area should be resected which results in a great stress for the patients. To overcome this problem, we focused in the near-infrared wavelength of 1000nm band which have high biological transmission. In this study, we developed a fluorescent clip which was realized with glass phosphor (Yb3+, Nd3+ doped to Bi2O3-B2O3 based glasses. λp: 976 nm, FWHM: 100 nm, size: 2x1x3 mm) and the laparoscopic fluorescent detection system for clip-derived near-infrared light. To evaluate clinical performance of a fluorescent clip and the laparoscopic fluorescent detection system, we used resected stomach (thickness: 13 mm) from the patients. Fluorescent clip was fixed on the gastric mucosa, and an excitation light (λ: 808 nm) was irradiated from outside of stomach for detection of fluorescence through stomach wall. As a result, fluorescence emission from the clip was successfully detected. Furthermore, we confirmed that detection sensitivity of the emission of fluorescence from the clip depends on the output power of the excitation light. We conformed that the fluorescent clip in combination with laparoscopic fluorescent detection system is very useful method to identify the exact location of the primary gastric cancer.

  10. Effects of molecular asymmetry of optically active molecules on the polarization properties of multiply scattered light

    NASA Astrophysics Data System (ADS)

    Vitkin, I. Alex; Laszlo, Richard D.; Whyman, Claire L.

    2002-02-01

    The use of polarized light for investigation of optically turbid systems has generated much recent interest since it has been shown that multiple scattering does not fully scramble the incident polarization states. It is possible under some conditions to measure polarization signals in diffusely scattered light, and use this information to characterize the structure or composition of the turbid medium. Furthermore, the idea of quantitative detection of optically active (chiral) molecules contained in such a system is attractive, particularly in clinical medicine where it may contribute to the development of a non-invasive method of glucose sensing in diabetic patients. This study uses polarization modulation and synchronous detection in the perpendicular and in the exact backscattering orientations to detect scattered light from liquid turbid samples containing varying amounts of L and D (left and right) isomeric forms of a chiral sugar. Polarization preservation increased with chiral concentrations in both orientations. In the perpendicular orientation, the optical rotation of the linearly polarized fraction also increased with the concentration of chiral solute, but in different directions for the two isomeric forms. There was no observed optical rotation in the exact backscattering geometry for either isomer. The presence of the chiral species is thus manifest in both detection directions, but the sense of the chiral asymmetry is not resolvable in retroreflection. The experiments show that useful information may be extracted from turbid chiral samples using polarized light.

  11. In vivo light scattering for the detection of cancerous and precancerous lesions of the cervix

    PubMed Central

    Mourant, Judith R.; Powers, Tamara M.; Bocklage, Thérese J.; Greene, Heather M.; Dorin, Maxine H.; Waxman, Alan G.; Zsemlye, Meggan M.; Smith, Harriet O.

    2009-01-01

    A non-invasive optical diagnostic system for detection of cancerous and precancerous lesions of the cervix was evaluated, in vivo. The optical system included a fiber optic probe designed to measure polarized and unpolarized light transport properties of a small volume of tissue. An algorithm for diagnosing tissue based on the optical measurements was developed which used four optical properties, three of which were related to light scattering properties and the fourth of which was related to hemoglobin concentration. A sensitivity of ∼77% and specificities in the mid 60's were obtained for separating high grade squamous intraepithelial lesions and cancer from other pathologies and normal tissue. The use of different cross-validation methods in algorithm development is analyzed and the relative difficulties of diagnosing certain pathologies is assessed. Furthermore, the robustness of the optical system for use by different doctors and to changes in fiber optic probe were also assessed and potential improvements in the optical system are discussed. PMID:19340117

  12. Increasing the efficiency of photon collection in LArTPCs: the ARAPUCA light trap

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cancelo, G.; Cavanna, F.; Escobar, C. O.

    The Liquid Argon Time Projection Chambers (LArTPCs) are a choice for the next generation of large neutrino detectors due to their optimal performance in particle tracking and calorimetry. The detection of Argon scintillation light plays a crucial role in the event reconstruction as well as the time reference for non-beam physics such as supernovae neutrino detection and baryon number violation studies. Here in this contribution, we present the current R&D work on the ARAPUCA (Argon R&D Advanced Program at UNICAMP), a light trap device to enhance Ar scintillation light collection and thus the overall performance of LArTPCs. The ARAPUCA workingmore » principle is based on a suitable combination of dichroic filters and wavelength shifters to achieve a high efficiency in light collection. We discuss the operational principles, the last results of laboratory tests and the application of the ARAPUCA as the alternative photon detection system in the protoDUNE detector.« less

  13. Increasing the efficiency of photon collection in LArTPCs: the ARAPUCA light trap

    DOE PAGES

    Cancelo, G.; Cavanna, F.; Escobar, C. O.; ...

    2018-03-26

    The Liquid Argon Time Projection Chambers (LArTPCs) are a choice for the next generation of large neutrino detectors due to their optimal performance in particle tracking and calorimetry. The detection of Argon scintillation light plays a crucial role in the event reconstruction as well as the time reference for non-beam physics such as supernovae neutrino detection and baryon number violation studies. Here in this contribution, we present the current R&D work on the ARAPUCA (Argon R&D Advanced Program at UNICAMP), a light trap device to enhance Ar scintillation light collection and thus the overall performance of LArTPCs. The ARAPUCA workingmore » principle is based on a suitable combination of dichroic filters and wavelength shifters to achieve a high efficiency in light collection. We discuss the operational principles, the last results of laboratory tests and the application of the ARAPUCA as the alternative photon detection system in the protoDUNE detector.« less

  14. Design and validation of a near-infrared fluorescence endoscope for detection of early esophageal malignancy

    NASA Astrophysics Data System (ADS)

    Waterhouse, Dale J.; Joseph, James; Neves, André A.; di Pietro, Massimiliano; Brindle, Kevin M.; Fitzgerald, Rebecca C.; Bohndiek, Sarah E.

    2016-08-01

    Barrett's esophagus is a known precursor lesion to esophageal adenocarcinoma. In these patients, early detection of premalignant disease, known as dysplasia, allows curative minimally invasive endoscopic therapy, but is confounded by a lack of contrast in white light endoscopy. Imaging fluorescently labeled lectins applied topically to the tissue has the potential to more accurately delineate dysplasia, but tissue autofluorescence limits both sensitivity and contrast when operating in the visible region. To overcome this challenge, we synthesized near-infrared (NIR) fluorescent wheat germ agglutinin (WGA-IR800CW) and constructed a clinically translatable bimodal NIR and white light endoscope. Images of NIR and white light with a field of view of 63 deg and an image resolution of 182 μm are coregistered and the honeycomb artifact arising from the fiber bundle is removed. A minimum detectable concentration of 110 nM was determined using a dilution series of WGA-IR800CW. We demonstrated ex vivo that this system can distinguish between gastric and squamous tissue types in mouse stomachs (p=0.0005) and accurately detect WGA-IR800CW fluorescence in human esophageal resections (compared with a gold standard imaging system, rs>0.90). Based on these findings, future work will optimize the bimodal endoscopic system for clinical trials in Barrett's surveillance.

  15. Microcontroller based driver alertness detection systems to detect drowsiness

    NASA Astrophysics Data System (ADS)

    Adenin, Hasibah; Zahari, Rahimi; Lim, Tiong Hoo

    2018-04-01

    The advancement of embedded system for detecting and preventing drowsiness in a vehicle is a major challenge for road traffic accident systems. To prevent drowsiness while driving, it is necessary to have an alert system that can detect a decline in driver concentration and send a signal to the driver. Studies have shown that traffc accidents usually occur when the driver is distracted while driving. In this paper, we have reviewed a number of detection systems to monitor the concentration of a car driver and propose a portable Driver Alertness Detection System (DADS) to determine the level of concentration of the driver based on pixelated coloration detection technique using facial recognition. A portable camera will be placed at the front visor to capture facial expression and the eye activities. We evaluate DADS using 26 participants and have achieved 100% detection rate with good lighting condition and a low detection rate at night.

  16. Electronic imaging system and technique

    DOEpatents

    Bolstad, J.O.

    1984-06-12

    A method and system for viewing objects obscurred by intense plasmas or flames (such as a welding arc) includes a pulsed light source to illuminate the object, the peak brightness of the light reflected from the object being greater than the brightness of the intense plasma or flame; an electronic image sensor for detecting a pulsed image of the illuminated object, the sensor being operated as a high-speed shutter; and electronic means for synchronizing the shutter operation with the pulsed light source.

  17. Electronic imaging system and technique

    DOEpatents

    Bolstad, Jon O.

    1987-01-01

    A method and system for viewing objects obscurred by intense plasmas or flames (such as a welding arc) includes a pulsed light source to illuminate the object, the peak brightness of the light reflected from the object being greater than the brightness of the intense plasma or flame; an electronic image sensor for detecting a pulsed image of the illuminated object, the sensor being operated as a high-speed shutter; and electronic means for synchronizing the shutter operation with the pulsed light source.

  18. System and Method for Multi-Wavelength Optical Signal Detection

    NASA Technical Reports Server (NTRS)

    McGlone, Thomas D. (Inventor)

    2017-01-01

    The system and method for multi-wavelength optical signal detection enables the detection of optical signal levels significantly below those processed at the discrete circuit level by the use of mixed-signal processing methods implemented with integrated circuit technologies. The present invention is configured to detect and process small signals, which enables the reduction of the optical power required to stimulate detection networks, and lowers the required laser power to make specific measurements. The present invention provides an adaptation of active pixel networks combined with mixed-signal processing methods to provide an integer representation of the received signal as an output. The present invention also provides multi-wavelength laser detection circuits for use in various systems, such as a differential absorption light detection and ranging system.

  19. Nondestructive and rapid detection of potato black heart based on machine vision technology

    NASA Astrophysics Data System (ADS)

    Tian, Fang; Peng, Yankun; Wei, Wensong

    2016-05-01

    Potatoes are one of the major food crops in the world. Potato black heart is a kind of defect that the surface is intact while the tissues in skin become black. This kind of potato has lost the edibleness, but it's difficult to be detected with conventional methods. A nondestructive detection system based on the machine vision technology was proposed in this study to distinguish the normal and black heart of potatoes according to the different transmittance of them. The detection system was equipped with a monochrome CCD camera, LED light sources for transmitted illumination and a computer. Firstly, the transmission images of normal and black heart potatoes were taken by the detection system. Then the images were processed by algorithm written with VC++. As the transmitted light intensity was influenced by the radial dimension of the potato samples, the relationship between the grayscale value and the potato radial dimension was acquired by analyzing the grayscale value changing rule of the transmission image. Then proper judging condition was confirmed to distinguish the normal and black heart of potatoes after image preprocessing. The results showed that the nondestructive system built coupled with the processing methods was accessible for the detection of potato black heart at a considerable accuracy rate. The transmission detection technique based on machine vision is nondestructive and feasible to realize the detection of potato black heart.

  20. Topographic data of selected areas along the Alabama River near Montgomery, Alabama, collected using mobile terrestrial light detection and ranging (T-LiDAR) technology

    USGS Publications Warehouse

    Kimbrow, D.R.

    2014-01-01

    Topographic data at selected areas within the Alabama River flood plain near Montgomery, Alabama, were collected using a truck-mounted mobile terrestrial light detection and ranging system. These data were collected for inclusion in a flood inundation model developed by the National Weather Service in Birmingham, Alabama. Data are presented as ArcGIS point shapefiles with the extension .shp.

  1. Relative Navigation Light Detection and Ranging (LIDAR) Sensor Development Test Objective (DTO) Performance Verification

    NASA Technical Reports Server (NTRS)

    Dennehy, Cornelius J.

    2013-01-01

    The NASA Engineering and Safety Center (NESC) received a request from the NASA Associate Administrator (AA) for Human Exploration and Operations Mission Directorate (HEOMD), to quantitatively evaluate the individual performance of three light detection and ranging (LIDAR) rendezvous sensors flown as orbiter's development test objective on Space Transportation System (STS)-127, STS-133, STS-134, and STS-135. This document contains the outcome of the NESC assessment.

  2. 4D light-field sensing system for people counting

    NASA Astrophysics Data System (ADS)

    Hou, Guangqi; Zhang, Chi; Wang, Yunlong; Sun, Zhenan

    2016-03-01

    Counting the number of people is still an important task in social security applications, and a few methods based on video surveillance have been proposed in recent years. In this paper, we design a novel optical sensing system to directly acquire the depth map of the scene from one light-field camera. The light-field sensing system can count the number of people crossing the passageway, and record the direction and intensity of rays at a snapshot without any assistant light devices. Depth maps are extracted from the raw light-ray sensing data. Our smart sensing system is equipped with a passive imaging sensor, which is able to naturally discern the depth difference between the head and shoulders for each person. Then a human model is built. Through detecting the human model from light-field images, the number of people passing the scene can be counted rapidly. We verify the feasibility of the sensing system as well as the accuracy by capturing real-world scenes passing single and multiple people under natural illumination.

  3. Fast, Large-Area, Wide-Bandgap UV Photodetector for Cherenkov Light Detection

    NASA Technical Reports Server (NTRS)

    Wrbanek, John D.; Wrbanek, Susan Y.

    2013-01-01

    Due to limited resources available for power and space for payloads, miniaturizing and integrating instrumentation is a high priority for addressing the challenges of manned and unmanned deep space missions to high Earth orbit (HEO), near Earth objects (NEOs), Lunar and Martian orbits and surfaces, and outer planetary systems, as well as improvements to high-altitude aircraft safety. New, robust, and compact detectors allow future instrumentation packages more options in satisfying specific mission goals. A solid-state ultraviolet (UV) detector was developed with a theoretical fast response time and large detection area intended for application to Cherenkov detectors. The detector is based on the wide-bandgap semiconductor zinc oxide (ZnO), which in a bridge circuit can detect small, fast pulses of UV light like those required for Cherenkov detectors. The goal is to replace the role of photomultiplier tubes in Cherenkov detectors with these solid-state devices, saving on size, weight, and required power. For improving detection geometry, a spherical detector to measure high atomic number and energy (HZE) ions from any direction has been patented as part of a larger space radiation detector system. The detector will require the development of solid-state UV photodetectors fast enough (2 ns response time or better) to detect the shockwave of Cherenkov light emitted as the ions pass through a quartz, sapphire, or acrylic ball. The detector must be small enough to fit in the detector system structure, but have an active area large enough to capture enough Cherenkov light from the sphere. The detector is fabricated on bulk single-crystal undoped ZnO. Inter - digitated finger electrodes and contact pads are patterned via photolithography, and formed by sputtered metal of silver, platinum, or other high-conductivity metal.

  4. Design and characterization of a dead-time regime enhanced early photon projection imaging system

    NASA Astrophysics Data System (ADS)

    Sinha, L.; Fogarty, M.; Zhou, W.; Giudice, A.; Brankov, J. G.; Tichauer, K. M.

    2018-04-01

    Scattering of visible and near-infrared light in biological tissue reduces spatial resolution for imaging of tissues thicker than 100 μm. In this study, an optical projection imaging system is presented and characterized that exploits the dead-time characteristics typical of photon counting modules based on single photon avalanche diodes (SPADs). With this system, it is possible to attenuate the detection of more scattered late-arriving photons, such that detection of less scattered early-arriving photons can be enhanced with increased light intensity, without being impeded by the maximum count rate of the SPADs. The system has the potential to provide transmittance-based anatomical information or fluorescence-based functional information (with slight modification in the instrumentation) of biological samples with improved resolution in the mesoscopic domain (0.1-2 cm). The system design, calibration, stability, and performance were evaluated using simulation and experimental phantom studies. The proposed system allows for the detection of very-rare early-photons at a higher frequency and with a better signal-to-noise ratio. The experimental results demonstrated over a 3.4-fold improvement in the spatial resolution using early photon detection vs. conventional detection, and a 1000-fold improvement in imaging time using enhanced early detection vs. conventional early photon detection in a 4-mm thick phantom with a tissue-equivalent absorption coefficient of μa = 0.05 mm-1 and a reduced scattering coefficient of μs' = 5 mm-1.

  5. Convolutional Neural Network-Based Human Detection in Nighttime Images Using Visible Light Camera Sensors.

    PubMed

    Kim, Jong Hyun; Hong, Hyung Gil; Park, Kang Ryoung

    2017-05-08

    Because intelligent surveillance systems have recently undergone rapid growth, research on accurately detecting humans in videos captured at a long distance is growing in importance. The existing research using visible light cameras has mainly focused on methods of human detection for daytime hours when there is outside light, but human detection during nighttime hours when there is no outside light is difficult. Thus, methods that employ additional near-infrared (NIR) illuminators and NIR cameras or thermal cameras have been used. However, in the case of NIR illuminators, there are limitations in terms of the illumination angle and distance. There are also difficulties because the illuminator power must be adaptively adjusted depending on whether the object is close or far away. In the case of thermal cameras, their cost is still high, which makes it difficult to install and use them in a variety of places. Because of this, research has been conducted on nighttime human detection using visible light cameras, but this has focused on objects at a short distance in an indoor environment or the use of video-based methods to capture multiple images and process them, which causes problems related to the increase in the processing time. To resolve these problems, this paper presents a method that uses a single image captured at night on a visible light camera to detect humans in a variety of environments based on a convolutional neural network. Experimental results using a self-constructed Dongguk night-time human detection database (DNHD-DB1) and two open databases (Korea advanced institute of science and technology (KAIST) and computer vision center (CVC) databases), as well as high-accuracy human detection in a variety of environments, show that the method has excellent performance compared to existing methods.

  6. Fiber optic inclination detector system having a weighted sphere with reference points

    DOEpatents

    Cwalinski, Jeffrey P.

    1995-01-01

    A fiber optic inclination detector system for determining the angular displacement of an object from a reference surface includes a simple mechanical transducer which requires a minimum number of parts and no electrical components. The system employs a single light beam which is split into two light beams and provided to the transducer. Each light beam is amplitude modulated upon reflecting off the transducer to detect inclination. The power values associated with each of the reflected light beams are converted by a pair of photodetectors into voltage signals, and a microprocessor manipulates the voltage signals to provide a measure of the angular displacement between the object and the reference surface.

  7. Object tracking via background subtraction for monitoring illegal activity in crossroad

    NASA Astrophysics Data System (ADS)

    Ghimire, Deepak; Jeong, Sunghwan; Park, Sang Hyun; Lee, Joonwhoan

    2016-07-01

    In the field of intelligent transportation system a great number of vision-based techniques have been proposed to prevent pedestrians from being hit by vehicles. This paper presents a system that can perform pedestrian and vehicle detection and monitoring of illegal activity in zebra crossings. In zebra crossing, according to the traffic light status, to fully avoid a collision, a driver or pedestrian should be warned earlier if they possess any illegal moves. In this research, at first, we detect the traffic light status of pedestrian and monitor the crossroad for vehicle pedestrian moves. The background subtraction based object detection and tracking is performed to detect pedestrian and vehicles in crossroads. Shadow removal, blob segmentation, trajectory analysis etc. are used to improve the object detection and classification performance. We demonstrate the experiment in several video sequences which are recorded in different time and environment such as day time and night time, sunny and raining environment. Our experimental results show that such simple and efficient technique can be used successfully as a traffic surveillance system to prevent accidents in zebra crossings.

  8. Detection of IL-6 by magnetic nanoparticles grown with the assistance of mid-infrared lighting.

    PubMed

    Jiang, Xiufeng; Zhang, Ye; Miao, Xiaofei; Li, Zenghui; Bao, Zengtao; Wang, Tong

    2013-01-01

    Nanomedical systems have attracted considerable attention primarily due to suitability in applications for specific cell selection through biomolecular targeting and rare cell detection enhancement in a diverse, multicellular population. In the present study, magnetic nanoparticles were prepared for use in high accuracy cell sensing. Magnetic nanoparticle growth was assisted by mid-infrared lighting. By this mechanism, a narrow window, estimated to be 2%, was achieved for the dimension distribution of grown nanoparticles. Combined with silicon nanowire (SiNW) transistors, a sensor with ultra high sensitivity for the detection of specific potential low abundance biomarkers has been achieved, which has been specifically used to detect interleukin-6 (IL-6) at extremely low concentrations. A novel biosensor with high sensitivity has been fabricated and utilized in the detection of IL-6 at 75 fM to 50 pM. The system consists of an SiNW transistor and magnetic nanoparticles with even dimension distribution. The novel sensor system is suitable for quantifying IL-6 at low concentrations in protein samples.

  9. Stable and general-purpose chemiluminescent detection system for horseradish peroxidase employing a thiazole compound enhancer and some additives.

    PubMed

    Iwata, R; Ito, H; Hayashi, T; Sekine, Y; Koyama, N; Yamaki, M

    1995-10-10

    A stable and highly sensitive chemiluminescent detection system for horseradish peroxidase (HRP)/luminol/hydrogen peroxide using a newly designed thiazole compound enhancer has been established. Some additives for the chemiluminescent reaction were explored to overcome some defects of the reaction such as rapid decay and high background of light emission. Recrystallization of luminol and the addition of several detergents into the reacting solution were effective to increase specific light emissions. The addition of skim milk into the reacting solution reduced the background. Consequently, skim milk combined with a detergent increased the signal to noise ratio about 20 times compared with the reactions in the absence of both additives. The optimal concentration of enhancer and the addition of egg albumin stabilized the emission. In the new method, 6x 10(-18) mol of HRP was detectable. This would be the most sensitive enhanced chemiluminescent detection system for HRP. Furthermore, we could detect picogram per milliliter (10(-17) mol) concentrations of a trace component in biological materials such as endothelin-1 by employing this reaction.

  10. A Label-Free Microfluidic Biosensor for Activity Detection of Single Microalgae Cells Based on Chlorophyll Fluorescence

    PubMed Central

    Wang, Junsheng; Sun, Jinyang; Song, Yongxin; Xu, Yongyi; Pan, Xinxiang; Sun, Yeqing; Li, Dongqing

    2013-01-01

    Detection of living microalgae cells is very important for ballast water treatment and analysis. Chlorophyll fluorescence is an indicator of photosynthetic activity and hence the living status of plant cells. In this paper, we developed a novel microfluidic biosensor system that can quickly and accurately detect the viability of single microalgae cells based on chlorophyll fluorescence. The system is composed of a laser diode as an excitation light source, a photodiode detector, a signal analysis circuit, and a microfluidic chip as a microalgae cell transportation platform. To demonstrate the utility of this system, six different living and dead algae samples (Karenia mikimotoi Hansen, Chlorella vulgaris, Nitzschia closterium, Platymonas subcordiformis, Pyramidomonas delicatula and Dunaliella salina) were tested. The developed biosensor can distinguish clearly between the living microalgae cells and the dead microalgae cells. The smallest microalgae cells that can be detected by using this biosensor are 3 μm ones. Even smaller microalgae cells could be detected by increasing the excitation light power. The developed microfluidic biosensor has great potential for in situ ballast water analysis. PMID:24287532

  11. During air cool process aerosol absorption detection with photothermal interferometry

    NASA Astrophysics Data System (ADS)

    Li, Baosheng; Xu, Limei; Huang, Junling; Ma, Fei; Wang, Yicheng; Li, Zhengqiang

    2014-11-01

    This paper studies the basic principle of laser photothermal interferometry method of aerosol particles absorption coefficient. The photothermal interferometry method with higher accuracy and lower uncertainty can directly measure the absorption coefficient of atmospheric aerosols and not be affected by scattered light. With Jones matrix expression, the math expression of a special polarization interferometer is described. This paper using folded Jamin interferometer, which overcomes the influence of vibration on measuring system. Interference come from light polarization beam with two orthogonal and then combine to one beam, finally aerosol absorption induced refractive index changes can be gotten with four beam of phase orthogonal light. These kinds of styles really improve the stability of system and resolution of the system. Four-channel detections interact with interference fringes, to reduce the light intensity `zero drift' effect on the system. In the laboratory, this device typical aerosol absorption index, it shows that the result completely agrees with actual value. After heated by laser, cool process of air also show the process of aerosol absorption. This kind of instrument will be used to monitor ambient aerosol absorption and suspended particulate matter chemical component. Keywords: Aerosol absorption coefficient; Photothermal interferometry; Suspended particulate matter.

  12. Design of Dual-Road Transportable Portal Monitoring System for Visible Light and Gamma-Ray Imaging

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Karnowski, Thomas Paul; Cunningham, Mark F; Goddard Jr, James Samuel

    2010-01-01

    The use of radiation sensors as portal monitors is increasing due to heightened concerns over the smuggling of fissile material. Transportable systems that can detect significant quantities of fissile material that might be present in vehicular traffic are of particular interest, especially if they can be rapidly deployed to different locations. To serve this application, we have constructed a rapid-deployment portal monitor that uses visible-light and gamma-ray imaging to allow simultaneous monitoring of multiple lanes of traffic from the side of a roadway. The system operation uses machine vision methods on the visible-light images to detect vehicles as they entermore » and exit the field of view and to measure their position in each frame. The visible-light and gamma-ray cameras are synchronized which allows the gamma-ray imager to harvest gamma-ray data specific to each vehicle, integrating its radiation signature for the entire time that it is in the field of view. Thus our system creates vehicle-specific radiation signatures and avoids source confusion problems that plague non-imaging approaches to the same problem. Our current prototype instrument was designed for measurement of upto five lanes of freeway traffic with a pair of instruments, one on either side of the roadway. Stereoscopic cameras are used with a third alignment camera for motion compensation and are mounted on a 50 deployable mast. In this paper we discuss the design considerations for the machine-vision system, the algorithms used for vehicle detection and position estimates, and the overall architecture of the system. We also discuss system calibration for rapid deployment. We conclude with notes on preliminary performance and deployment.« less

  13. Design of dual-road transportable portal monitoring system for visible light and gamma-ray imaging

    NASA Astrophysics Data System (ADS)

    Karnowski, Thomas P.; Cunningham, Mark F.; Goddard, James S.; Cheriyadat, Anil M.; Hornback, Donald E.; Fabris, Lorenzo; Kerekes, Ryan A.; Ziock, Klaus-Peter; Bradley, E. Craig; Chesser, J.; Marchant, W.

    2010-04-01

    The use of radiation sensors as portal monitors is increasing due to heightened concerns over the smuggling of fissile material. Transportable systems that can detect significant quantities of fissile material that might be present in vehicular traffic are of particular interest, especially if they can be rapidly deployed to different locations. To serve this application, we have constructed a rapid-deployment portal monitor that uses visible-light and gamma-ray imaging to allow simultaneous monitoring of multiple lanes of traffic from the side of a roadway. The system operation uses machine vision methods on the visible-light images to detect vehicles as they enter and exit the field of view and to measure their position in each frame. The visible-light and gamma-ray cameras are synchronized which allows the gamma-ray imager to harvest gamma-ray data specific to each vehicle, integrating its radiation signature for the entire time that it is in the field of view. Thus our system creates vehicle-specific radiation signatures and avoids source confusion problems that plague non-imaging approaches to the same problem. Our current prototype instrument was designed for measurement of upto five lanes of freeway traffic with a pair of instruments, one on either side of the roadway. Stereoscopic cameras are used with a third "alignment" camera for motion compensation and are mounted on a 50' deployable mast. In this paper we discuss the design considerations for the machine-vision system, the algorithms used for vehicle detection and position estimates, and the overall architecture of the system. We also discuss system calibration for rapid deployment. We conclude with notes on preliminary performance and deployment.

  14. Aircraft Alerting Systems Criteria Study. Volume II. Human Factors Guidelines for Aircraft Alerting Systems

    DTIC Science & Technology

    1977-05-01

    Effect of Mixing Flashing and Steady Irrelevant Lights, Ergonomics, Vol. 6 (3), 1963, pp. 27-294. Creelman , C. D., Detection of Signals of Uncertain...Frequency, Acoustical Sok. America-J, Vol. 32 (7), July 1960, pp. 805-10. Creelman , C. D., Detection, Discrimination, and Loudness of Short Tones

  15. Road Lane Detection Robust to Shadows Based on a Fuzzy System Using a Visible Light Camera Sensor

    PubMed Central

    Hoang, Toan Minh; Baek, Na Rae; Cho, Se Woon; Kim, Ki Wan; Park, Kang Ryoung

    2017-01-01

    Recently, autonomous vehicles, particularly self-driving cars, have received significant attention owing to rapid advancements in sensor and computation technologies. In addition to traffic sign recognition, road lane detection is one of the most important factors used in lane departure warning systems and autonomous vehicles for maintaining the safety of semi-autonomous and fully autonomous systems. Unlike traffic signs, road lanes are easily damaged by both internal and external factors such as road quality, occlusion (traffic on the road), weather conditions, and illumination (shadows from objects such as cars, trees, and buildings). Obtaining clear road lane markings for recognition processing is a difficult challenge. Therefore, we propose a method to overcome various illumination problems, particularly severe shadows, by using fuzzy system and line segment detector algorithms to obtain better results for detecting road lanes by a visible light camera sensor. Experimental results from three open databases, Caltech dataset, Santiago Lanes dataset (SLD), and Road Marking dataset, showed that our method outperformed conventional lane detection methods. PMID:29143764

  16. Digital micromirror devices in Raman trace detection of explosives

    NASA Astrophysics Data System (ADS)

    Glimtoft, Martin; Svanqvist, Mattias; Ågren, Matilda; Nordberg, Markus; Östmark, Henric

    2016-05-01

    Imaging Raman spectroscopy based on tunable filters is an established technique for detecting single explosives particles at stand-off distances. However, large light losses are inherent in the design due to sequential imaging at different wavelengths, leading to effective transmission often well below 1 %. The use of digital micromirror devices (DMD) and compressive sensing (CS) in imaging Raman explosives trace detection can improve light throughput and add significant flexibility compared to existing systems. DMDs are based on mature microelectronics technology, and are compact, scalable, and can be customized for specific tasks, including new functions not available with current technologies. This paper has been focusing on investigating how a DMD can be used when applying CS-based imaging Raman spectroscopy on stand-off explosives trace detection, and evaluating the performance in terms of light throughput, image reconstruction ability and potential detection limits. This type of setup also gives the possibility to combine imaging Raman with non-spatially resolved fluorescence suppression techniques, such as Kerr gating. The system used consists of a 2nd harmonics Nd:YAG laser for sample excitation, collection optics, DMD, CMOScamera and a spectrometer with ICCD camera for signal gating and detection. Initial results for compressive sensing imaging Raman shows a stable reconstruction procedure even at low signals and in presence of interfering background signal. It is also shown to give increased effective light transmission without sacrificing molecular specificity or area coverage compared to filter based imaging Raman. At the same time it adds flexibility so the setup can be customized for new functionality.

  17. Enhancing the sensitivity of slow light MZI biosensors through multi-hole defects

    NASA Astrophysics Data System (ADS)

    Qin, Kun; Zhao, Yiliang; Hu, Shuren; Weiss, Sharon M.

    2018-02-01

    We demonstrate enhanced detection sensitivity of a slow light Mach-Zehnder interferometer (MZI) sensor by incorporating multi-hole defects (MHDs). Slow light MZI biosensors with a one-dimensional photonic crystal in one arm have been previously shown to improve the performance of traditional MZI sensors based on the increased lightmatter interaction that takes place in the photonic crystal region of the structure. Introducing MHDs in the photonic crystal region increases the available surface area for molecular attachment and further increases the enhanced lightmatter interaction capability of slow light MZIs. The MHDs allow analyte to interact with a greater fraction of the guided wave in the MZI. For a slow light MHD MZI sensor with a 16 μm long sensing arm, a bulk sensitivity of 151,000 rad/RIU-cm is demonstrated experimentally, which is approximately two-fold higher than our previously reported slow light MZI sensors and thirteen-fold higher than traditional MZI biosensors with millimeter length sensing regions. For the label-free detection of nucleic acids, the slow light MZI with MHDs also exhibits a two-fold sensitivity improvement in experiment compared to the slow light MZI without MHDs. Because the detection sensitivity of slow light MHD MZIs scales with the length of the sensing arm, the tradeoff between detection limit and device size can be appropriately mitigated for different applications. All experimental results presented in this work are in good agreement with finite difference-time domain-calculations. Overall, the slow light MZI biosensors with MHDs are a promising platform for highly sensitive and multiplexed lab-on-chip systems.

  18. Method and system for controlling the position of a beam of light

    DOEpatents

    Steinkraus, Jr., Robert F.; Johnson, Gary W [Livermore, CA; Ruggiero, Anthony J [Livermore, CA

    2011-08-09

    An method and system for laser beam tracking and pointing is based on a conventional position sensing detector (PSD) or quadrant cell but with the use of amplitude-modulated light. A combination of logarithmic automatic gain control, filtering, and synchronous detection offers high angular precision with exceptional dynamic range and sensitivity, while maintaining wide bandwidth. Use of modulated light enables the tracking of multiple beams simultaneously through the use of different modulation frequencies. It also makes the system resistant to interfering light sources such as ambient light. Beam pointing is accomplished by feeding back errors in the measured beam position to a beam steering element, such as a steering mirror. Closed-loop tracking performance is superior to existing methods, especially under conditions of atmospheric scintillation.

  19. Development of a wireless, self-sustaining damage detection sensor system based on chemiluminescence for structural health monitoring

    NASA Astrophysics Data System (ADS)

    Kuang, K. S. C.

    2014-03-01

    A novel application of chemiluminescence resulting from the chemical reaction in a glow-stick as sensors for structural health monitoring is demonstrated here. By detecting the presence of light emitting from these glow-sticks, it is possible to develop a low-cost sensing device with the potential to provide early warning of damage in a variety of engineering applications such as monitoring of cracks or damage in concrete shear walls, detecting of ground settlement, soil liquefaction, slope instability, liquefaction-related damage of underground structure and others. In addition, this paper demonstrates the ease of incorporating wireless capability to the sensor device and the possibility of making the sensor system self-sustaining by means of a renewable power source for the wireless module. A significant advantage of the system compared to previous work on the use of plastic optical fibre (POF) for damage detection is that here the system does not require an electrically-powered light source. Here, the sensing device, embedded in a cement host, is shown to be capable of detecting damage. A series of specimens with embedded glow-sticks have been investigated and an assessment of their damage detection capability will be reported. The specimens were loaded under flexure and the sensor responses were transmitted via a wireless connection.

  20. Liquid scintillator composition optimization for use in ultra-high energy cosmic ray detector systems

    NASA Astrophysics Data System (ADS)

    Beznosko, Dmitriy; Batyrkhanov, Ayan; Iakovlev, Alexander; Yelshibekov, Khalykbek

    2017-06-01

    The Horizon-T (HT) detector system and the currently under R&D HT-KZ detector system are designed for the detection of Extensive Air Showers (EAS) with energies above ˜1016 eV (˜1017 eV for HT-KZ). The main challenges in both detector systems are the fast time resolutions needed for studying the temporary structure of EAS, and the extremely wide dynamic range needed to study the spatial distribution of charged particles in EAS disks. In order to detect the low-density of charged particles far from the EAS axis, a large-area detector is needed. Liquid scintillator with low cost would be a possible solution for such a detector, including the recently developed safe and low-cost water-based liquid scintillators. Liquid organic scintillators give a fast and high light yield (LY) for charged particle detection. It is similar to plastic scintillator in properties but is cost effective for large volumes. With liquid scintillator, one can create detection volumes that are symmetric and yet retain high LY detection. Different wavelength shifters affect the scintillation light by changing the output spectrum into the best detection region. Results of the latest studies of the components optimization in the liquid scintillator formulae are presented.

  1. Fiberoptic spectrophotometer

    DOEpatents

    Tans, Petrus P.; Lashof, Daniel A.

    1986-01-01

    A device for determining the relative composition of a sample of a gas by comparison of the Raman-scattered light of the sample with that of a known gas comprising: a means for passing a single light source through the unknown and the known gases, choppers to alternate the Raman-scattered light into a common light detection and measuring system, optical fiber networks for spatially mixing the resulting Raman scattered light from each sample and directing the mixed light to selective detectors, and a compiler to record the light intensity of each wavelength of Raman-scattered light as a function of the sample from which it originated.

  2. Tools for Observing our Universe

    NASA Technical Reports Server (NTRS)

    Woolack, Ed

    2007-01-01

    A selection of hands on demonstrations related to the detection of light will be presented to middle and high school instructors. The primary emphasis of the talk will be on conveying how scientists use light to remotely observe and understand the properties of astrophysical systems.

  3. Hyperspectral reflectance and fluorescence line-scan imaging system for online detection of fecal contamination on apples

    NASA Astrophysics Data System (ADS)

    Kim, Moon S.; Cho, Byoung-Kwan; Yang, Chun-Chieh; Chao, Kaunglin; Lefcourt, Alan M.; Chen, Yud-Ren

    2006-10-01

    We have developed nondestructive opto-electronic imaging techniques for rapid assessment of safety and wholesomeness of foods. A recently developed fast hyperspectral line-scan imaging system integrated with a commercial apple-sorting machine was evaluated for rapid detection of animal feces matter on apples. Apples obtained from a local orchard were artificially contaminated with cow feces. For the online trial, hyperspectral images with 60 spectral channels, reflectance in the visible to near infrared regions and fluorescence emissions with UV-A excitation, were acquired from apples moving at a processing sorting-line speed of three apples per second. Reflectance and fluorescence imaging required a passive light source, and each method used independent continuous wave (CW) light sources. In this paper, integration of the hyperspectral imaging system with the commercial applesorting machine and preliminary results for detection of fecal contamination on apples, mainly based on the fluorescence method, are presented.

  4. Neuronal Organization of Deep Brain Opsin Photoreceptors in Adult Teleosts

    PubMed Central

    Hang, Chong Yee; Kitahashi, Takashi; Parhar, Ishwar S.

    2016-01-01

    Biological impacts of light beyond vision, i.e., non-visual functions of light, signify the need to better understand light detection (or photoreception) systems in vertebrates. Photopigments, which comprise light-absorbing chromophores bound to a variety of G-protein coupled receptor opsins, are responsible for visual and non-visual photoreception. Non-visual opsin photopigments in the retina of mammals and extra-retinal tissues of non-mammals play an important role in non-image-forming functions of light, e.g., biological rhythms and seasonal reproduction. This review highlights the role of opsin photoreceptors in the deep brain, which could involve conserved neurochemical systems that control different time- and light-dependent physiologies in in non-mammalian vertebrates including teleost fish. PMID:27199680

  5. Modular optical detector system

    DOEpatents

    Horn, Brent A [Livermore, CA; Renzi, Ronald F [Tracy, CA

    2006-02-14

    A modular optical detector system. The detector system is designed to detect the presence of molecules or molecular species by inducing fluorescence with exciting radiation and detecting the emitted fluorescence. Because the system is capable of accurately detecting and measuring picomolar concentrations it is ideally suited for use with microchemical analysis systems generally and capillary chromatographic systems in particular. By employing a modular design, the detector system provides both the ability to replace various elements of the detector system without requiring extensive realignment or recalibration of the components as well as minimal user interaction with the system. In addition, the modular concept provides for the use and addition of a wide variety of components, including optical elements (lenses and filters), light sources, and detection means, to fit particular needs.

  6. Design and implementation of green intelligent lights based on the ZigBee

    NASA Astrophysics Data System (ADS)

    Gan, Yong; Jia, Chunli; Zou, Dongyao; Yang, Jiajia; Guo, Qianqian

    2013-03-01

    By analysis of the low degree of intelligence of the traditional lighting control methods, the paper uses the singlechip microcomputer for the control core, and uses a pyroelectric infrared technology to detect the existence of the human body, light sensors to sense the light intensity; the interface uses infrared sensor module, photosensitive sensor module, relay module to transmit the signal, which based on ZigBee wireless network. The main function of the design is to realize that the lighting can intelligently adjust the brightness according to the indoor light intensity when people in door, and it can turn off the light when people left. The circuit and program design of this system is flexible, and the system achieves the effect of intelligent energy saving control.

  7. Noise suppression for the differential detection in nuclear magnetic resonance gyroscope

    NASA Astrophysics Data System (ADS)

    Yang, Dan; Zhou, Binquan; Chen, LinLin; Jia, YuChen; Lu, QiLin

    2017-10-01

    The nuclear magnetic resonance gyroscope is based on spin-exchange optical pumping of noble gases to detect and measure the angular velocity of the carrier, but it would be challenging to measure the precession signal of noble gas nuclei directly. To solve the problem, the primary detection method utilizes alkali atoms, the precession of nuclear magnetization modulates the alkali atoms at the Larmor frequency of nuclei, relatively speaking, and it is easier to detect the precession signal of alkali atoms. The precession frequency of alkali atoms is detected by the rotation angle of linearly polarized probe light; and differential detection method is commonly used in NMRG in order to detect the linearly polarized light rotation angle. Thus, the detection accuracy of differential detection system will affect the sensitivity of the NMRG. For the purpose of further improvement of the sensitivity level of the NMRG, this paper focuses on the aspects of signal detection, and aims to do an error analysis as well as an experimental research of the linearly light rotation angle detection. Through the theoretical analysis and the experimental illustration, we found that the extinction ratio σ2 and DC bias are the factors that will produce detective noise in the differential detection method.

  8. Feasibility study of microwave modulation DIAL system for global CO II monitoring

    NASA Astrophysics Data System (ADS)

    Hirano, Yoshihito; Kameyama, Shumpei; Ueno, Shinichi; Sugimoto, Nobuo; Kimura, Toshiyoshi

    2006-12-01

    A new concept of DIAL (DIfferential Absorption Lidar) system for global CO II monitoring using microwave modulation is introduced. This system uses quasi-CW lights which are intensity modulated in microwave region and receives a backscattered light from the ground. In this system, ON/OFF wavelength laser lights are modulated with microwave frequencies, and received lights of two wavelengths are able to be discriminated by modulation frequencies in electrical signal domain. Higher sensitivity optical detection can be realized compared with the conventional microwave modulation lidar by using direct down conversion of modulation frequency. The system also has the function of ranging by using pseudo-random coding in modulation. Fiber-based optical circuit using wavelength region of 1.6 micron is a candidate for the system configuration. After the explanation of this configuration, feasibility study of this system on the application to global CO II monitoring is introduced.

  9. Stand-off detection of explosives vapors by resonance-enhanced Raman spectroscopy

    NASA Astrophysics Data System (ADS)

    Johansson, Ida; Ceco, Ema; Ehlerding, Anneli; Östmark, Henric

    2013-06-01

    This paper describes a system for stand-off vapor detection based on Resonant Raman spectroscopy, RRS. The system is a step towards a RRS LIDAR (Light Detection And Ranging) system, capable of detecting vapors from explosives and explosives precursors at long distances. The current system was used to detect the vapor of nitromethane and mononitrotoluene outdoors in the open air, at a stand-off distance of 11-13 meters. Also, the signal dependence upon irradiation wavelength and sample concentration was studied in controlled laboratory conditions. A tunable Optical Parametric Oscillator pumped by an Nd:YAG laser, with a pulse length of 6 ns, was operated in the UV range of interest, 210-400 nm, illuminating the sample vapor. The backscattered Raman signal was collected by a telescope and a roundto- slit optical fiber was used to transmit collected light to the spectrometer with minimum losses. A gated intensified charge-coupled device (ICCD) registered the spectra. The nitromethane cross section was resonance enhanced more than a factor 30 700, when measured at 220 nm, compared to the 532 nm value. The results show that a decrease in concentration can have a positive effect on the sensitivity of the system, due to a decrease in absorption and selfabsorption in the sample.

  10. Infrared techniques for detecting carbonization at onset of device failure

    NASA Astrophysics Data System (ADS)

    Farr, Norman; Sinofsky, Edward L.

    1997-05-01

    We describe the design, and development of an infrared detection system which detects the onset of carbonization of fluoropolymers in the presence of up to 60 watts of 1.06 micrometer laser energy. This system is used to shut down a therapeutic laser system before significant damage is done to a laser delivery device and patient. Black body radiation emitting from the diffusion tip is transmitted, backwards, through the same optical fiber as the therapeutic wavelength. Using a high power 1.06 micrometer laser mirror at 45 degrees, most of the 1.06 micrometer light is reflected while the black body radiation is passed to a holographic notch filter which further filters the signal. Still more filtering was needed before the 1.1 to 2 micrometer signal could be detected within the presence the therapeutic light using an extended indium gallium arsenide photodetector. There was still a significant detected offset which increased with laser power which necessitated a means to automatically null the offset for different laser power settings. The system is designed to be used with any unmodified laser system. It interfaces directly to or in series with most common external safety interlocks and can be used with various diffusing tips, probes or bare fibers.

  11. Fiber optic light-scattering measurement system for evaluation of embryo viability: model experiment

    NASA Astrophysics Data System (ADS)

    Itoh, Harumi; Arai, Tsunenori; Kikuchi, Makoto

    1996-05-01

    We evaluated the particle density detectability and particle size detectivity of our fiber-optic light-scattering measurement system. In order to prevent the multiple pregnancy on current in vitro fertilization-embryo transfer, we have aimed to develop a new quantitative and non- invasive method to select a single viable human embryo. We employed the measurement of mitochondria localization in an embryo, which may have the correlation with development ability. We applied the angular distribution measurement of the light-scattering intensity from the embryo to obtain the information originated from the mitochondria. The latex spheres with a diameter of 1.0 micrometers were used to simulate the scattering intensity of the mitochondria. The measurement probes of our system consisted of two fibers for illumination and sensing. They were arranged at a right angle to a microscope optical axis to measure the angular distribution of the light-scattering intensity. We observed that the light-scattering intensity increased monotonically in the range from 106 to 1010 particles per ml. Since the mitochondria density in a human embryo corresponded to 2.5 X 107 per ml in the measurement chamber, we may measure the mitochondria density in the human embryo. The angular dependence of light-scattering intensity changed with the sphere diameters. This result showed the possibility of the selective measurement of the mitochondria density in the embryo in spite of the presence of the other cell organelle. We think that our light-scattering measurement system might be applicable to the evaluation method for the embryo viability.

  12. Programmable Spectral Source and Design Tool for 3D Imaging Using Complementary Bandpass Filters

    NASA Technical Reports Server (NTRS)

    Bae, Youngsam (Inventor); Korniski, Ronald J. (Inventor); Ream, Allen (Inventor); Shearn, Michael J. (Inventor); Shahinian, Hrayr Karnig (Inventor); Fritz, Eric W. (Inventor)

    2017-01-01

    An endoscopic illumination system for illuminating a subject for stereoscopic image capture, includes a light source which outputs light; a first complementary multiband bandpass filter (CMBF) and a second CMBF, the first and second CMBFs being situated in first and second light paths, respectively, where the first CMBF and the second CMBF filter the light incident thereupon to output filtered light; and a camera which captures video images of the subject and generates corresponding video information, the camera receiving light reflected from the subject and passing through a pupil CMBF pair and a detection lens. The pupil CMBF includes a first pupil CMBF and a second pupil CMBF, the first pupil CMBF being identical to the first CMBF and the second pupil CMBF being identical to the second CMBF, and the detection lens includes one unpartitioned section that covers both the first pupil CMBF and the second pupil CMBF.

  13. A novel multiwavelength fluorescence image-guided surgery imaging system

    NASA Astrophysics Data System (ADS)

    Volpi, D.; Tullis, I. D. C.; Laios, A.; Pathiraja, P. N. J.; Haldar, K.; Ahmed, A. A.; Vojnovic, B.

    2014-02-01

    We describe the development and performance analysis of two clinical near-infrared fluorescence image-guided surgery (FIGS) devices that aim to overcome some of the limitations of current FIGS systems. The devices operate in a widefield-imaging mode and can work (1) in conjunction with a laparoscope, during minimally invasive surgery, and (2) as a hand-held, open surgery imaging system. In both cases, narrow-band excitation light, delivered at multiple wavelengths, is efficiently combined with white reflectance light. Light is delivered to ~100 cm2 surgical field at 1-2 mW/cm2 for white light and 3-7 mW/cm2 (depending on wavelength) of red - near infrared excitation, at a typical working distance of 350 mm for the hand-held device and 100 mm for the laparoscope. A single, sensitive, miniaturized color camera collects both fluorescence and white reflectance light. The use of a single imager eliminates image alignment and software overlay complexity. A novel filtering and illumination arrangement allows simultaneous detection of white reflectance and fluorescence emission from multiple dyes in real-time. We will present both fluorescence detection sensitivity modeling and practical performance data. We have demonstrated the efficiency and the advantages of the devices both pre-clinically and during live surgery on humans. Both the hand-held and the laparoscopic systems have proved to be reliable and beneficial in an ongoing clinical trial involving sentinel lymph node detection in gynecological cancers. We will show preliminary results using two clinically approved dyes, Methylene blue and indocyanine green. We anticipate that this technology can be integrated and routinely used in a larger variety of surgical procedures.

  14. Pine Beetle Detection

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Earth Systems Science Office scientists worked with officials in St. Tammany Parish, La., to detect and battle pine beetle infestation in Fontainebleu State Park. The scientists used a new method of detecting plant stress by using special lenses and modified sensors to detect a change in light levels given off by the plant before the stress is visible to the naked eye.

  15. Fiber optic sensor system for detecting movement or position of a rotating wheel bearing

    DOEpatents

    Veeser, Lynn R.; Rodriguez, Patrick J.; Forman, Peter R.; Monahan, Russell E.; Adler, Jonathan M.

    1997-01-01

    An improved fiber optic sensor system and integrated sensor bearing assembly for detecting movement or position of a rotating wheel bearing having a multi-pole tone ring which produces an alternating magnetic field indicative of movement and position of the rotating member. A magneto-optical material, such as a bismuth garnet iron (B.I.G.) crystal, having discrete magnetic domains is positioned in the vicinity of the tone ring so that the domains align themselves to the magnetic field generated by the tone ring. A single fiber optic cable, preferably single mode fiber, carries light generated by a source of light to the B.I.G. crystal. The light passes through the B.I.G. crystal and is refracted at domain boundaries in the crystal. The intensity of the refracted light is indicative of the amount of alignment of the domains and therefore the strength of the magnetic field. The refracted light is carried by the fiber optic cable to an optic receiver where the intensity is measured and an electrical signal is generated and sent to a controller indicating the frequency of the changes in light intensity and therefore the rotational speed of the rotating wheel bearing.

  16. Application of thermoluminescence for detection of cascade shower 1: Hardware and software of reader system

    NASA Technical Reports Server (NTRS)

    Akashi, M.; Kawaguchi, S.; Watanabe, Z.; Misaki, A.; Niwa, M.; Okamoto, Y.; Fujinaga, T.; Ichimura, M.; Shibata, T.; Dake, S.

    1985-01-01

    A reader system for the detection of cascade showers via luminescence induced by heating sensitive material (BaSO4:Eu) is developed. The reader system is composed of following six instruments: (1) heater, (2) light guide, (3) image intensifier, (4) CCD camera, (5) image processor, (6) microcomputer. The efficiency of these apparatuses and software application for image analysis is reported.

  17. Real-time optically sectioned wide-field microscopy employing structured light illumination and a CMOS detector

    NASA Astrophysics Data System (ADS)

    Mitic, Jelena; Anhut, Tiemo; Serov, Alexandre; Lasser, Theo; Bourquin, Stephane

    2003-07-01

    Real-time optically sectioned microscopy is demonstrated using an AC-sensitive detection concept realized with smart CMOS image sensor and structured light illumination by a continuously moving periodic pattern. We describe two different detection systems based on CMOS image sensors for the detection and on-chip processing of the sectioned images in real time. A region-of-interest is sampled at high frame rate. The demodulated signal delivered by the detector corresponds to the depth discriminated image of the sample. The measured FWHM of the axial response depends on the spatial frequency of the projected grid illumination and is in the μm-range. The effect of using broadband incoherent illumination is discussed. The performance of these systems is demonstrated by imaging technical as well as biological samples.

  18. Surgical instrument biocontaminant fluorescence detection in ambient lighting conditions for hospital reprocessing and sterilization department (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Baribeau, François; Bubel, Annie; Dumont, Guillaume; Vachon, Carl; Lépine, André; Rochefort, Stéphane; Massicotte, Martin; Buteau-Vaillancourt, Louis; Gallant, Pascal; Mermut, Ozzy

    2017-03-01

    Hospitals currently rely on simple human visual inspection for assessing cleanliness of surgical instruments. Studies showed that surgical site infections are in part attributed to inadequate cleaning of medical devices. Standards groups recognize the need to objectively quantify the amount of residues on surgical instruments and establish guidelines. We developed a portable technology for the detection of contaminants on surgical instruments through fluorescence following cleaning. Weak fluorescence signals are usually detected in the obscurity only with the lighting of the excitation source. The key element of this system is that it works in ambient lighting conditions, a requirement to not disturb the normal workflow of hospital reprocessing facilities. A biocompatible fluorescent dye is added to the detergent and labels the proteins of organic residues. It is resistant to the harsh environment in a washer-disinfector. Two inspection devices have been developed with a 488nm laser as the excitation source: a handheld scanner and a tabletop station using spectral-domain and time-domain ambient light cancellation schemes. The systems are eye safe and equipped with image processing and interfacing software to provide visual or audible warnings to the operator based on a set of adjustable signal thresholds. Micron-scale residues are detected by the system which can also evaluate soil size and mass. Unlike swabbing, it can inspect whole tools in real-time. The technology has been validated in an independent hospital decontamination research laboratory. It also has potential applications in the forensics, agro-food, and space fields. Technical aspects and results will be presented and discussed.

  19. A flexible and miniaturized hair dye based photodetector via chemiluminescence pathway.

    PubMed

    Lin, Ching-Chang; Sun, Da-Shiuan; Lin, Ya-Lin; Tsai, Tsung-Tso; Cheng, Chieh; Sun, Wen-Hsien; Ko, Fu-Hsiang

    2017-04-15

    A flexible and miniaturized metal semiconductor metal (MSM) biomolecular photodetector was developed as the core photocurrent system through chemiluminescence for hydrogen peroxide sensing. The flexible photocurrent sensing system was manufactured on a 30-µm-thick crystalline silicon chip by chemical etching process, which produced a flexible silicon chip. A surface texturization design on the flexible device enhanced the light-trapping effect and minimized reflectivity losses from the incident light. The model protein streptavidin bound to horseradish peroxidase (HRP) was successfully immobilized onto the sensor surface through high-affinity conjugation with biotin. The luminescence reaction occurred with luminol, hydrogen peroxide and HRP enzyme, and the emission of light from the catalytic reaction was detected by underlying flexible photodetector. The chemiluminescence in the miniaturized photocurrent sensing system was successfully used to determine the hydrogen peroxide concentration in real-time analyses. The hydrogen peroxide detection limit of the flexible MSM photodetector was 2.47mM. The performance of the flexible MSM photodetector maintained high stability under bending at various bending radii. Moreover, for concave bending, a significant improvement in detection signal intensity (14.5% enhancement compared with a flat configuration) was observed because of the increased photocurrent, which was attributed to enhancement of light trapping. Additionally, this detector was used to detect hydrogen peroxide concentrations in commercial hair dye products, which is a significant issue in the healthcare field. The development of this novel, flexible and miniaturized MSM biomolecular photodetector with excellent mechanical flexibility and high sensitivity demonstrates the applicability of this approach to future wearable sensor development efforts. Copyright © 2016 Elsevier B.V. All rights reserved.

  20. Measurement device for high-precision spectral transmittance of solar blind filter

    NASA Astrophysics Data System (ADS)

    Wang, Yan; Qian, Yunsheng; Lv, Yang; Feng, Cheng; Liu, Jian

    2017-02-01

    In order to measure spectral transmittance of solar-blind filter ranging from ultraviolet to visible light accurately, a high-precision filter transmittance measuring system based on the ultraviolet photomultiplier is developed. The calibration method is mainly used to measure transmittance in this system, which mainly consists of an ultraviolet photomultiplier as core of the system and a lock-in amplifier combined with an optical modulator as the aided measurement for the system. The ultraviolet photomultiplier can amplify the current signal through the filter and have the characteristics of low dark current and high luminance gain. The optical modulator and the lock-in amplifier can obtain the signal from the photomultiplier and inhibit dark noise and spurious signal effectively. Through these two parts, the low light passing through the filters can be detected and we can calculate the transmittance by the optical power detected. Based on the proposed system, the limit detection of the transmittance can reach 10-12, while the result of the conventional approach is merely 10-6. Therefore, the system can make an effective assessment of solar blind ultraviolet filters.

  1. Optical readout of displacements of nanowires along two mutually perpendicular directions

    NASA Astrophysics Data System (ADS)

    Fu, Chenghua

    2017-05-01

    Nanowires are good force transducers due to their low mass. The singleness of the direction of the motion detection in a certain system is an existing limitation, and to overcome the limitation is the key point in this article. Optical methods, such as polarized light interferometry and light scattering, are generally used for detecting the displacement of nanowires. Typically, either light interference or light scattering is considered when relating the displacement of a nanowire with the photodetector's measurements. In this work, we consider both the light interference along the optical axis and light scattering perpendicular to the optical axis of a micro-lens fiber optic interferometer. Identifying the displacement along the two directions and the corresponding vibration conversion efficiency coefficients for the nanowire is a significant part of our study. Our analysis shows that the optimal working point of the micro-lens fiber optic interferometer can realize the detection of displacement along the optical axis without the disturbance coming from the motion perpendicular to the optical axis, and vice versa. We use Mie scattering theory to calculate the scattering light for the reason that the size of the nanowire is comparable to the wavelength of light. Our results could provide a guide for optical readout experiments of the displacement of nanowires.

  2. Dirt detection on brown eggs by means of color computer vision.

    PubMed

    Mertens, K; De Ketelaere, B; Kamers, B; Bamelis, F R; Kemps, B J; Verhoelst, E M; De Baerdemaeker, J G; Decuypere, E M

    2005-10-01

    In the last 20 yr, different methods for detecting defects in eggs were developed. Until now, no satisfying technique existed to sort and quantify dirt on eggshells. The work presented here focuses on the design of an off-line computer vision system to differentiate and quantify the presence of different dirt stains on brown eggs: dark (feces), white (uric acid), blood, and yolk stains. A system that provides uniform light exposure around the egg was designed. In this uniform light, pictures of dirty and clean eggs were taken, stored, and analyzed. The classification was based on a few standard logical operators, allowing for a quick implementation in an online set-up. In an experiment, 100 clean and 100 dirty eggs were used to validate the classification algorithm. The designed vision system showed an accuracy of 99% for the detection of dirt stains. Two percent of the clean eggs had a light-colored eggshell and were subsequently mistaken for showing large white stains. The accuracy of differentiation of the different kinds of dirt stains was 91%. Of the eggs with dark stains, 10.81% were mistaken for having bloodstains, and 33.33% of eggs with bloodstains were mistaken for having dark stains. The developed system is possibly a first step toward an on line dirt evaluation technique for brown eggs.

  3. Investigation to improve the resolution and range of a light imaging system for very thick tissues

    NASA Astrophysics Data System (ADS)

    Wist, Abund O.; Moon, Peter; Herr, Steven L.; Fatouros, Panos P.

    1995-05-01

    A high resolution light imaging system has been developed utilizing an HeNe (628 nm, 32 mW) and a receiver with post collimation mounted on an x, y table to scan the object. The image can be either recorded on a film or stored in a computer for display on a terminal. Tests show that the system in the regular mode is capable of detecting the spine and soft tissues in anesthetized mice, and of transilluminating fully an adult skull bone with a resolution for details better than one third mm. In teeth, all regular carious lesions, including incipient lesions larger than one third of a mm, can be seen in front or in the back of the tooth, none of which could be detected by dental x-ray systems. Applying a new high resolution mode, the resolution can be increased in teeth to less than 0.1 mm. Some difficulty still exists in detecting small lesions on occlusal or approximal surfaces.

  4. Laser-ultraviolet-A-induced ultraweak photon emission in mammalian cells.

    PubMed

    Niggli, Hugo J; Tudisco, Salvatore; Privitera, Giuseppe; Applegate, Lee Ann; Scordino, Agata; Musumeci, Franco

    2005-01-01

    Photobiological research in the last 30 yr has shown the existence of ultraweak photon emission in biological tissue, which can be detected with sophisticated photomultiplier systems. Although the emission of this ultraweak radiation, often termed biophotons, is extremely low in mammalian cells, it can be efficiently increased by ultraviolet light. Most recently it was shown that UV-A (330 to 380 nm) releases such very weak cell radiation in differentiated human skin fibroblasts. Based on these findings, a new and powerful tool in the form of UV-A-laser-induced biophotonic emission of cultured cells was developed with the intention to detect biophysical changes between carcinogenic and normal cells. With suspension densities ranging from 1 to 8 x 10(6) cells/mL, it was evident that an increase of the UV-A-laser-light induced photon emission intensity could be observed in normal as well as melanoma cells. Using this new detection procedure of ultraweak light emission, photons in cell suspensions as low as 100 microL could be determined, which is a factor of 100 lower compared to previous procedures. Moreover, the detection procedure has been further refined by turning off the photomultiplier system electronically during irradiation leading to the first measurements of induced light emission in the cells after less than 10 micros instead of 150 ms, as reported in previous procedures. This improvement leads to measurements of light bursts up 10(7) photons/s instead of several hundred as found with classical designs. Overall, we find decreasing induction ratings between normal and melanoma cells as well as cancer-prone and melanoma cells. Therefore, it turns out that this highly sensitive and noninvasive device enables us to detect high levels of ultraweak photon emission following UV-A-laser-induced light stimulation within the cells, which enables future development of new biophysical strategies in cell research. Copyright 2005 Society of Photo-Optical Instrumentation Engineers.

  5. Multimodal sensing strategies for detecting transparent barriers indoors from a mobile platform

    NASA Astrophysics Data System (ADS)

    Acevedo, Isaiah; Kleine, R. Kaleb; Kraus, Dustan; Mascareñas, David

    2015-04-01

    There is currently an interest in developing mobile sensing platforms that fly indoors. The primary goal for these platforms is to be able to successfully navigate a building under various lighting and environmental conditions. There are numerous research challenges associated with this goal, one of which is the platform's ability to detect and identify the presence of transparent barriers. Transparent barriers could include windows, glass partitions, or skylights. For example, in order to successfully navigate inside of a structure, these platforms will need to sense if a space contains a transparent barrier and whether or not this space can be traversed. This project's focus has been developing a multimodal sensing system that can successfully identify such transparent barriers under various lighting conditions while aboard a mobile platform. Along with detecting transparent barriers, this sensing platform is capable of distinguishing between reflective, opaque, and transparent barriers. It will be critical for this system to be able to identify transparent barriers in real-time in order for the navigation system to maneuver accordingly. The properties associated with the interaction between various frequencies of light and transparent materials were one of the techniques leveraged to solve this problem.

  6. Non-classical light generated by quantum-noise-driven cavity optomechanics.

    PubMed

    Brooks, Daniel W C; Botter, Thierry; Schreppler, Sydney; Purdy, Thomas P; Brahms, Nathan; Stamper-Kurn, Dan M

    2012-08-23

    Optomechanical systems, in which light drives and is affected by the motion of a massive object, will comprise a new framework for nonlinear quantum optics, with applications ranging from the storage and transduction of quantum information to enhanced detection sensitivity in gravitational wave detectors. However, quantum optical effects in optomechanical systems have remained obscure, because their detection requires the object’s motion to be dominated by vacuum fluctuations in the optical radiation pressure; so far, direct observations have been stymied by technical and thermal noise. Here we report an implementation of cavity optomechanics using ultracold atoms in which the collective atomic motion is dominantly driven by quantum fluctuations in radiation pressure. The back-action of this motion onto the cavity light field produces ponderomotive squeezing. We detect this quantum phenomenon by measuring sub-shot-noise optical squeezing. Furthermore, the system acts as a low-power, high-gain, nonlinear parametric amplifier for optical fluctuations, demonstrating a gain of 20 dB with a pump corresponding to an average of only seven intracavity photons. These findings may pave the way for low-power quantum optical devices, surpassing quantum limits on position and force sensing, and the control and measurement of motion in quantum gases.

  7. Cross Matching of VIIRS Boat Detection and Vessel Monitoring System Tracks

    NASA Astrophysics Data System (ADS)

    Hsu, F. C.; Elvidge, C.; Zhizhin, M. N.; Baugh, K.; Ghosh, T.

    2016-12-01

    One approach to commercial fishing is to use use bright lights at night to attract catch. This is a widely used practice in East and Southeast Asia, but can also be found in other fisheries. In some cases, the deployed lighting exceeds 100,000 watts. Such lighting is distinctive in dark ocean and can even be seen from space with sensor such as Visible Infrared Imaging Radiometer Suite Day/Night Band (VIIRS-DNB). We have developed a VIIRS Boat Detection (VBD) system, which outputs lists of boat locations in near real time. One of the standard methods fishery agencies use to collect geospatial data on fishing boats is to require boats to carry Vessel Monitoring System beacons. We developed an algorithm to cross-match VBD data with VMS tracks. With this we are able to identify fishing boats that do not carry VMS beacons. In certain situations, this is an indicator of illegal fishing. The other application for this cross-matching is to define the VIIRS detection limits and developing a calibration to estimate deployed wattage. Here we demonstrate results of cross matching VBD and VMS for Indonesia as example to showcase its potential.

  8. Detection of TNT using a sensitive two-photon organic dendrimer for remote sensing

    NASA Astrophysics Data System (ADS)

    Narayanan, Aditya; Varnavski, Oleg; Mongin, Oliver; Majoral, Jean-Pierre; Blanchard-Desce, Mireille; Goodson, Theodore, III

    2008-03-01

    There is currently a need for superior stand-off detection schemes for protection against explosive weapons of mass destruction. Fluorescence detection at small distances from the target has proven to be attractive. A novel unexplored route in fluorescence chemical sensing that utilizes the exceptional spectroscopic capabilities of nonlinear optical methods is two-photon excited fluorescence. This approach utilizes infra-red light for excitation of remote sensors. Infra-red light suffers less scattering in porous materials which is beneficial for vapor sensing and has greater depth of penetration through the atmosphere, and there are fewer concerns regarding eye safety in remote detection schemes. We demonstrate this method using a novel dendritic system which possesses both excellent fluorescence sensitivity to the presence of TNT with infra-red pulses of light and high two-photon absorption (TPA) response. This illustrates the use of TPA for potential stand-off detection of energetic materials in the infra-red spectral regions in a highly two-photon responsive dendrimer.

  9. Simulation of a method to directly image exoplanets around multiple stars systems

    NASA Astrophysics Data System (ADS)

    Thomas, Sandrine J.; Bendek, Eduardo; Belikov, Ruslan

    2014-08-01

    Direct imaging of extra-solar planets has now become a reality, especially with the deployment and commissioning of the first generation of specialized ground-based instruments such as the GPI, SPHERE, P1640 and SCExAO. These systems will allow detection of planets 107 times fainter than their host star. For space- based missions, such as EXCEDE, EXO-C, EXO-S, WFIRST/AFTA, different teams have shown in laboratories contrasts reaching 10-10 within a few diffraction limits from the star using a combination of a coronagraph to suppress light coming from the host star and a wavefront control system. These demonstrations use a de- formable mirror (DM) to remove residual starlight (speckles) created by the imperfections of telescope. However, all these current and future systems focus on detecting faint planets around a single host star or unresolved bi- naries/multiples, while several targets or planet candidates are located around nearby binary stars such as our neighbor star Alpha Centauri. Until now, it has been thought that removing the light of a companion star is impossible with current technology, excluding binary star systems from target lists of direct imaging missions. Direct imaging around binaries/multiple systems at a level of contrast allowing Earth-like planet detection is challenging because the region of interest, where a dark zone is essential, is contaminated by the light coming from the hosts star companion. We propose a method to simultaneously correct aberrations and diffraction of light coming from the target star as well as its companion star in order to reveal planets orbiting the target star. This method works even if the companion star is outside the control region of the DM (beyond its half-Nyquist frequency), by taking advantage of aliasing effects.

  10. Liquid-phase chromatography detector

    DOEpatents

    Voigtman, E.G.; Winefordner, J.D.; Jurgensen, A.R.

    1983-11-08

    A liquid-phase chromatography detector comprises a flow cell having an inlet tubular conduit for receiving a liquid chromatographic effluent and discharging it as a flowing columnar stream onto a vertically adjustable receiving surface spaced apart from and located vertically below and in close proximity to the discharge end of the tubular conduit; a receiver adapted to receive liquid overflowing from the receiving surface; an exit conduit for continuously removing liquid from the receiver; a light source for focusing fluorescence-producing light pulses on the flowing columnar stream as it passes from the outlet of the conduit to the receiving surface and a fluorescence detector to detect the produced fluorescence; a source of light pulse for producing acoustic waves in the columnar stream as it passes from the conduit outlet to the receiving surface; and a piezoelectric transducer adapted to detect those waves; and a source of bias voltage applied to the inlet tubular conduit and adapted to produce ionization of the liquid flowing through the flow cell so as to produce photocurrents therein and an electrical system to detect and record the photocurrents. This system is useful in separating and detecting individual chemical compounds from mixtures thereof. 5 figs.

  11. Liquid-phase chromatography detector

    DOEpatents

    Voigtman, Edward G.; Winefordner, James D.; Jurgensen, Arthur R.

    1983-01-01

    A liquid-phase chromatography detector comprising a flow cell having an inlet tubular conduit for receiving a liquid chromatographic effluent and discharging it as a flowing columnar stream onto a vertically adjustable receiving surface spaced apart from and located vertically below and in close proximity to the discharge end of the tubular conduit; a receiver adapted to receive liquid overflowing from the receiving surface; an exit conduit for continuously removing liquid from the receiver; a light source for focussing fluorescence-producing light pulses on the flowing columnar stream as it passes from the outlet of the conduit to the receiving surface and a fluorescence detector to detect the produced fluorescence; a source of light pulse for producing acoustic waves in the columnar stream as it passes from the conduit outlet to the receiving surface; and a piezoelectric transducer adapted to detect those waves; and a source of bias voltage applied to the inlet tubular conduit and adapted to produce ionization of the liquid flowing through the flow cell so as to produce photocurrents therein and an electrical system to detect and record the photocurrents. This system is useful in separating and detecting individual chemical compounds from mixtures thereof.

  12. Ocular Screening System

    NASA Technical Reports Server (NTRS)

    1987-01-01

    Used to detect eye problems in children through analysis of retinal reflexes, the system incorporates image processing techniques. VISISCREEN's photorefractor is basically a 35 millimeter camera with a telephoto lens and an electronic flash. By making a color photograph, the system can test the human eye for refractive error and obstruction in the cornea or lens. Ocular alignment problems are detected by imaging both eyes simultaneously. Electronic flash sends light into the eyes and the light is reflected from the retina back to the camera lens. Photorefractor analyzes the retinal reflexes generated by the subject's response to the flash and produces an image of the subject's eyes in which the pupils are variously colored. The nature of a defect, where such exists, is identifiable by atrained observer's visual examination.

  13. Compact and high resolution virtual mouse using lens array and light sensor

    NASA Astrophysics Data System (ADS)

    Qin, Zong; Chang, Yu-Cheng; Su, Yu-Jie; Huang, Yi-Pai; Shieh, Han-Ping David

    2016-06-01

    Virtual mouse based on IR source, lens array and light sensor was designed and implemented. Optical architecture including lens amount, lens pitch, baseline length, sensor length, lens-sensor gap, focal length etc. was carefully designed to achieve low detective error, high resolution, and simultaneously, compact system volume. System volume is 3.1mm (thickness) × 4.5mm (length) × 2, which is much smaller than that of camera-based device. Relative detective error of 0.41mm and minimum resolution of 26ppi were verified in experiments, so that it can replace conventional touchpad/touchscreen. If system thickness is eased to 20mm, resolution higher than 200ppi can be achieved to replace real mouse.

  14. Influence of skin type and wavelength on light wave reflectance.

    PubMed

    Fallow, Bennett A; Tarumi, Takashi; Tanaka, Hirofumi

    2013-06-01

    A new application of photoplethysmography (PPG) has emerged recently to provide the possibility of heart rate monitoring without a telemetric chest strap. The aim of this study was to determine if a new device could detect pulsation over a broad range of skin types, and what light wavelength would be most suitable for detecting the signals. A light emitting diode-based PPG system was used to detect changes in pulsatile blood flow on 23 apparently healthy individuals (11 male and 12 female, 20-59 years old) of varying skin types classified according to a questionnaire in combination with digital photographs with a skin type chart. Four different light wavelengths (470, 520, 630, and 880 nm) were tested. Normalized modulation level is calculated as the AC/DC component ratio and represents the change in flow over the underlying constant state of flow or perfusion. In the resting condition, green light wavelength (520 nm) displayed greater modulation (p < 0.001) than all the other wavelengths analyzed regardless of skin types. Type V (dark brown) skin type was significantly lower in modulation than all other skin types. In the exercise condition, both blue (470 nm) and green (520 nm) light wavelengths displayed greater signal-to-noise ratios than red (630 nm) or infrared (880 nm) light wavelengths (p < 0.001). We concluded that a PPG-based device can detect pulsation across all skin types and that a greater resolution was obtained using a green light wavelength at rest and a green or blue light wavelength during exercise.

  15. New photolysis system for NO2 measurements in the lower stratosphere

    NASA Technical Reports Server (NTRS)

    Gao, R. S.; Keim, E. R.; Woodbridge, E. L.; Ciciora, S. J.; Proffitt, M. H.; Thompson, T. L.; Mclaughlin, R. J.; Fahey, D. W.

    1994-01-01

    A new system for NO2 detection has been developed for use on the NASA ER-2 aircraft. The system converts NO2 to NO using UV photolysis with the NO product subsequently detected with an on-board chemiluminescence detector. The new system is compact, light weight, has high time resolution (approximately 1 s), and is significantly more efficient then some previous designs. Details of the system design and airborne performance are discussed.

  16. Towards a disposable in vivo miniature implantable fluorescence detector

    NASA Astrophysics Data System (ADS)

    Bellis, Stephen; Jackson, J. Carlton; Mathewson, Alan

    2006-02-01

    In the field of fluorescent microscopy, neuronal activity, diabetes and drug treatment are a few of the wide ranging biomedical applications that can be monitored with the use of dye markers. Historically, in-vivo fluorescent detectors consist of implantable probes coupled by optical fibre to sophisticated bench-top instrumentation. These systems typically use laser light to excite the fluorescent marker dies and using sensors, such as the photo-multiplier tube (PMT) or charge coupled devices (CCD), detect the fluorescent light that is filtered from the total excitation. Such systems are large and expensive. In this paper we highlight the first steps toward a fully implantable in-vivo fluorescence detection system. The aim is to make the detector system small, low cost and disposable. The current prototype is a hybrid platform consisting of a vertical cavity surface emitting laser (VCSEL) to provide the excitation and a filtered solid state Geiger mode avalanche photo-diode (APD) to detect the emitted fluorescence. Fluorescence detection requires measurement of extremely low levels of light so the proposed APD detectors combine the ability to count individual photons with the added advantage of being small in size. At present the exciter and sensor are mounted on a hybrid PCB inside a 3mm diameter glass tube.This is wired to external electronics, which provide quenching, photon counting and a PC interface. In this configuration, the set-up can be used for in-vitro experimentation and in-vivo analysis conducted on animals such as mice.

  17. Enhanced coupling of light into a turbid medium through microscopic interface engineering

    PubMed Central

    Thompson, Jonathan V.; Hokr, Brett H.; Kim, Wihan; Ballmann, Charles W.; Applegate, Brian E.; Jo, Javier; Yamilov, Alexey; Cao, Hui; Scully, Marlan O.; Yakovlev, Vladislav V.

    2017-01-01

    There are many optical detection and sensing methods used today that provide powerful ways to diagnose, characterize, and study materials. For example, the measurement of spontaneous Raman scattering allows for remote detection and identification of chemicals. Many other optical techniques provide unique solutions to learn about biological, chemical, and even structural systems. However, when these systems exist in a highly scattering or turbid medium, the optical scattering effects reduce the effectiveness of these methods. In this article, we demonstrate a method to engineer the geometry of the optical interface of a turbid medium, thereby drastically enhancing the coupling efficiency of light into the material. This enhanced optical coupling means that light incident on the material will penetrate deeper into (and through) the medium. It also means that light thus injected into the material will have an enhanced interaction time with particles contained within the material. These results show that, by using the multiple scattering of light in a turbid medium, enhanced light–matter interaction can be achieved; this has a direct impact on spectroscopic methods such as Raman scattering and fluorescence detection in highly scattering regimes. Furthermore, the enhanced penetration depth achieved by this method will directly impact optical techniques that have previously been limited by the inability to deposit sufficient amounts of optical energy below or through highly scattering layers. PMID:28701381

  18. Performance of a newly designed continuous soot monitoring system (COSMOS).

    PubMed

    Miyazaki, Yuzo; Kondo, Yutaka; Sahu, Lokesh K; Imaru, Junichi; Fukushima, Nobuhiko; Kano, Minoru

    2008-10-01

    We designed a continuous soot monitoring system (COSMOS) for fully automated, high-sensitivity, continuous measurement of light absorption by black carbon (BC) aerosols. The instrument monitors changes in transmittance across an automatically advancing quartz fiber filter tape using an LED at a 565 nm wavelength. To achieve measurements with high sensitivity and a lower detectable light absorption coefficient, COSMOS uses a double-convex lens and optical bundle pipes to maintain high light intensity and signal data are obtained at 1000 Hz. In addition, sampling flow rate and optical unit temperature are actively controlled. The inlet line for COSMOS is heated to 400 degrees C to effectively volatilize non-refractory aerosol components that are internally mixed with BC. In its current form, COSMOS provides BC light absorption measurements with a detection limit of 0.45 Mm(-1) (0.045 microg m(-3) for soot) for 10 min. The unit-to-unit variability is estimated to be within +/- 1%, demonstrating its high reproducibility. The absorption coefficients determined by COSMOS agreed with those by a particle soot absorption photometer (PSAP) to within 1% (r2 = 0.97). The precision (+/- 0.60 Mm(-1)) for 10 min integrated data was better than that of PSAP and an aethalometer under our operating conditions. These results showed that COSMOS achieved both an improved detection limit and higher precision for the filter-based light absorption measurements of BC compared to the existing methods.

  19. Portable light transmission measuring system for preserved corneas.

    PubMed

    Ventura, Liliane; Jesus, Gabriel Torres de; Oliveira, Gunter Camilo Dablas de; Sousa, Sidney J F

    2005-12-22

    The authors have developed a small portable device for the objective measurement of the transparency of corneas stored in preservative medium, for use by eye banks in evaluation prior to transplantation. The optical system consists of a white light, lenses, and pinholes that collimate the white light beams and illuminate the cornea in its preservative medium, and an optical filter (400-700 nm) that selects the range of the wavelength of interest. A sensor detects the light that passes through the cornea, and the average corneal transparency is displayed. In order to obtain only the tissue transparency, an electronic circuit was built to detect a baseline input of the preservative medium prior to the measurement of corneal transparency. The operation of the system involves three steps: adjusting the "0 %" transmittance of the instrument, determining the "100 %" transmittance of the system, and finally measuring the transparency of the preserved cornea inside the storage medium. Fifty selected corneas were evaluated. Each cornea was submitted to three evaluation methods: subjective classification of transparency through a slit lamp, quantification of the transmittance of light using a corneal spectrophotometer previously developed, and measurement of transparency with the portable device. By comparing the three methods and using the expertise of eye bank trained personnel, a table for quantifying corneal transparency with the new device has been developed. The correlation factor between the corneal spectrophotometer and the new device is 0,99813, leading to a system that is able to standardize transparency measurements of preserved corneas, which is currently done subjectively.

  20. Consequences of on-line dialysis on polyelectrolyte molar masses determined by size-exclusion chromatography with light scattering detection.

    PubMed

    Radke, Wolfgang

    2016-02-01

    Size-exclusion chromatography with light scattering detection experiments conducted on poly(acrylic acid) neutralized to different degrees or using hydroxides with different counterions suggest that the same counterion and degree of neutralization is observed at the detector, irrespective of salt concentration, degree of neutralization and counterion at the time of injection. This strongly supports that during the chromatographic experiment the counterions of the polyelectrolyte are exchanged with those of the eluent, resulting in an effective dialysis of the polyelectrolyte solution during the size-exclusion chromatography experiment. Consequently, the refractive index increment determined by a refractive index detector equals the refractive index increment obtained after excessive dialysis against the pure eluent. Therefore, the species detected and characterized by light scattering coupled to size-exclusion chromatography are not identical to the species injected into the chromatographic system. Despite this structural change during the chromatographic experiments, the correct molar mass for the injected species is obtained by size-exclusion chromatography with light scattering detection. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Semiconductor sensors

    NASA Technical Reports Server (NTRS)

    Gatos, Harry C. (Inventor); Lagowski, Jacek (Inventor)

    1977-01-01

    A semiconductor sensor adapted to detect with a high degree of sensitivity small magnitudes of a mechanical force, presence of traces of a gas or light. The sensor includes a high energy gap (i.e., .about. 1.0 electron volts) semiconductor wafer. Mechanical force is measured by employing a non-centrosymmetric material for the semiconductor. Distortion of the semiconductor by the force creates a contact potential difference (cpd) at the semiconductor surface, and this cpd is determined to give a measure of the force. When such a semiconductor is subjected to illumination with an energy less than the energy gap of the semiconductors, such illumination also creates a cpd at the surface. Detection of this cpd is employed to sense the illumination itself or, in a variation of the system, to detect a gas. When either a gas or light is to be detected and a crystal of a non-centrosymmetric material is employed, the presence of gas or light, in appropriate circumstances, results in a strain within the crystal which distorts the same and the distortion provides a mechanism for qualitative and quantitative evaluation of the gas or the light, as the case may be.

  2. Impact of various color LED flashlights and different lighting source to skin distances on the manual and the computer-aided detection of basal cell carcinoma borders.

    PubMed

    Bakht, Mohamadreza K; Pouladian, Majid; Mofrad, Farshid B; Honarpisheh, Hamid

    2014-02-01

    Quantitative analysis based on digital skin image has been proven to be helpful in dermatology. Moreover, the borders of the basal cell carcinoma (BCC) lesions have been challenging borders for the automatic detection methods. In this work, a computer-aided dermatoscopy system was proposed to enhance the clinical detection of BCC lesion borders. Fifty cases of BCC were selected and 2000 pictures were taken. The lesion images data were obtained with eight colors of flashlights and in five different lighting source to skin distances (SSDs). Then, the image-processing techniques were used for automatic detection of lesion borders. Further, the dermatologists marked the lesions on the obtained photos. Considerable differences between the obtained values referring to the photographs that were taken at super blue and aqua green color lighting were observed for most of the BCC borders. It was observed that by changing the SSD, an optimum distance could be found where that the accuracy of the detection reaches to a maximum value. This study clearly indicates that by changing SSD and lighting color, manual and automatic detection of BCC lesions borders can be enhanced. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. Detection of partial-thickness tears in ligaments and tendons by Stokes-polarimetry imaging

    NASA Astrophysics Data System (ADS)

    Kim, Jihoon; John, Raheel; Walsh, Joseph T.

    2008-02-01

    A Stokes polarimetry imaging (SPI) system utilizes an algorithm developed to construct degree of polarization (DoP) image maps from linearly polarized light illumination. Partial-thickness tears of turkey tendons were imaged by the SPI system in order to examine the feasibility of the system to detect partial-thickness rotator cuff tear or general tendon pathology. The rotating incident polarization angle (IPA) for the linearly polarized light provides a way to analyze different tissue types which may be sensitive to IPA variations. Degree of linear polarization (DoLP) images revealed collagen fiber structure, related to partial-thickness tears, better than standard intensity images. DoLP images also revealed structural changes in tears that are related to the tendon load. DoLP images with red-wavelength-filtered incident light may show tears and related organization of collagen fiber structure at a greater depth from the tendon surface. Degree of circular polarization (DoCP) images exhibited well the horizontal fiber orientation that is not parallel to the vertically aligned collagen fibers of the tendon. The SPI system's DOLP images reveal alterations in tendons and ligaments, which have a tissue matrix consisting largely of collagen, better than intensity images. All polarized images showed modulated intensity as the IPA was varied. The optimal detection of the partial-thickness tendon tears at a certain IPA was observed. The SPI system with varying IPA and spectral information can improve the detection of partial-thickness rotator cuff tears by higher visibility of fiber orientations and thereby improve diagnosis and treatment of tendon related injuries.

  4. An intraoperative spectroscopic imaging system for quantification of Protoporphyrin IX during glioma surgery (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Angulo-Rodríguez, Leticia M.; Laurence, Audrey; Jermyn, Michael; Sheehy, Guillaume; Sibai, Mira; Petrecca, Kevin; Roberts, David W.; Paulsen, Keith D.; Wilson, Brian C.; Leblond, Frédéric

    2016-03-01

    Cancer tissue often remains after brain tumor resection due to the inability to detect the full extent of cancer during surgery, particularly near tumor boundaries. Commercial systems are available for intra-operative real-time aminolevulenic acid (ALA)-induced protoporphyrin IX (PpIX) fluorescence imaging. These are standard white-light neurosurgical microscopes adapted with optical components for fluorescence excitation and detection. However, these instruments lack sensitivity and specificity, which limits the ability to detect low levels of PpIX and distinguish it from tissue auto-fluorescence. Current systems also cannot provide repeatable and un-biased quantitative fluorophore concentration values because of the unknown and highly variable light attenuation by tissue. We present a highly sensitive spectroscopic fluorescence imaging system that is seamlessly integrated onto a neurosurgical microscope. Hardware and software were developed to achieve through-microscope spatially-modulated illumination for 3D profilometry and to use this information to extract tissue optical properties to correct for the effects of tissue light attenuation. This gives pixel-by-pixel quantified fluorescence values and improves detection of low PpIX concentrations. This is achieved using a high-sensitivity Electron Multiplying Charge Coupled Device (EMCCD) with a Liquid Crystal Tunable Filter (LCTF) whereby spectral bands are acquired sequentially; and a snapshot camera system with simultaneous acquisition of all bands is used for profilometry and optical property recovery. Sensitivity and specificity to PpIX is demonstrated using brain tissue phantoms and intraoperative human data acquired in an on-going clinical study using PpIX fluorescence to guide glioma resection.

  5. Detection of Extraterrestrial Civilizations via the Spectral Signature of Advanced Interstellar Spacecraft

    NASA Astrophysics Data System (ADS)

    Zubrin, Robert

    1994-07-01

    This paper examines the possibility of detecting extraterrestrial civilizations by means of searching for the spectral signature of their interstellar transportation systems. The advantage of such an approach is that the characteristic power levels associated with interstellar transportation systems are many orders of magnitude greater than those required for communication, and so the signal strength may be much greater. Furthermore, unlike communication which is governed by a fairly arbitrary selection of technology and mutually agreed upon conventions, interstellar transportation systems are governed much more stringently by the laws of physics. For purposes of the present analysis we consider 4 methods of interstellar propulsion, the principles of which are fairly well understood. These are anti-matter rockets, fusion rockets, fission rockets, all of which can be used to either accelerate or decelerate a spacecraft, and magnetic sails, which can be used to decelerate a spacecraft by creating drag against the interstellar medium. The types of radiation emitted by each of these propulsion systems is described, and the signal strength for starships of a characteristic mass of 1 million tonnes traveling at speeds and acceleration levels characteristic of the various propulsion systems is estimated. It is shown that for the power level of ships considered, the high energy gamma radiation emitted by the anti-matter, fusion and fission propulsion systems would be undetectable at interstellar distances. Better opportunities for detection would be the bremsstrahlung radiation from the plasma confinement systems of fusion devices, which might be detectable at distances of about 1 light year, and visible light emitted from the radiators of anti-matter driven photon rocket, which might be detectable by the Hubble Space Telescope at a distance of several hundred light years provided the rocket nozzle is oriented towards the Earth. The most detectable form of starship radiation, however, was found to be the low frequency radio emissions of cyclotron radiation caused by interaction of the interstellar medium with a magnetic sail. The frequency of such radiation is given approximately by f=120(v/c)kHz, where v is the starship's velocity. Because the frequency of this radiation is lower than the Earth's ionospheric cut-off, an antenna for its reception would have to be space-based. However such a space-based antenna with a 6 km effective diameter could detect the magsail emission of a characteristic starship at distances of up to several thousand light years. Both photon rockets and magnetic sails would emit a signal that could easily be distinguished from natural sources. We conclude that the detection of extraterrestrial civilizations via the spectral signature of their spacecraft is possible in principle and recommend that the approach be studied further.

  6. White Light Schlieren Optics Using Bacteriorhodopsin as an Adaptive Image Grid

    NASA Technical Reports Server (NTRS)

    Peale, Robert; Ruffin, Boh; Donahue, Jeff; Barrett, Carolyn

    1996-01-01

    A Schlieren apparatus using a bacteriorhodopsin film as an adaptive image grid with white light illumination is demonstrated for the first time. The time dependent spectral properties of the film are characterized. Potential applications include a single-ended Schlieren system for leak detection.

  7. Standoff detection of explosives: a challenging approach for optical technologies

    NASA Astrophysics Data System (ADS)

    Désilets, S.; Hô, N.; Mathieu, P.; Simard, J. R.; Puckrin, E.; Thériault, J. M.; Lavoie, H.; Théberge, F.; Babin, F.; Gay, D.; Forest, R.; Maheux, J.; Roy, G.; Châteauneuf, M.

    2011-06-01

    Standoff detection of explosives residues on surfaces at few meters was made using optical technologies based on Raman scattering, Laser-Induced Breakdown Spectroscopy (LIBS) and passive standoff FTIR radiometry. By comparison, detection and analysis of nanogram samples of different explosives was made with a microscope system where Raman scattering from a micron-size single point illuminated crystal of explosive was observed. Results from standoff detection experiments using a telescope were compared to experiments using a microscope to find out important parameters leading to the detection. While detection and spectral identification of the micron-size explosive particles was possible with a microscope, standoff detection of these particles was very challenging due to undesired light reflected and produced by the background surface or light coming from other contaminants. Results illustrated the challenging approach of detecting at a standoff distance the presence of low amount of micron or submicron explosive particles.

  8. Dust-concentration measurement based on Mie scattering of a laser beam

    PubMed Central

    Yu, Xiaoyu; Shi, Yunbo; Wang, Tian; Sun, Xu

    2017-01-01

    To realize automatic measurement of the concentration of dust particles in the air, a theory for dust concentration measurement was developed, and a system was designed to implement the dust concentration measurement method based on laser scattering. In the study, the principle of dust concentration detection using laser scattering is studied, and the detection basis of Mie scattering theory is determined. Through simulation, the influence of the incident laser wavelength, dust particle diameter, and refractive index of dust particles on the scattered light intensity distribution are obtained for determining the scattered light intensity curves of single suspended dust particles under different characteristic parameters. A genetic algorithm was used to study the inverse particle size distribution, and the reliability of the measurement system design is proven theoretically. The dust concentration detection system, which includes a laser system, computer circuitry, air flow system, and control system, was then implemented according to the parameters obtained from the theoretical analysis. The performance of the designed system was evaluated. Experimental results show that the system performance was stable and reliable, resulting in high-precision automatic dust concentration measurement with strong anti-interference ability. PMID:28767662

  9. Light-Based Triggering and Reconstruction of Michel Electrons in LArIAT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Foreman, W.

    2016-01-19

    The LArIAT Experiment aims to calibrate the liquid argon time projection chamber (LArTPC) using a beam of charged particles at the Fermilab Test Beam Facility. It is equipped with a novel scintillation light readout system using PMTs and custom SiPM preamplifier boards to detect light from reflector foils coated with wavelength-shifting TPB. A trigger on delayed secondary flashes of light captures events containing stopping cosmic muons together with the Michel electrons coming from their subsequent decay. This dedicated Michel trigger supplies an abundant sample of low-energy electrons throughout the detector's active volume, providing opportunities to study the combined calorimetric capabilitiesmore » of the light system and the TPC. Preliminary results using scintillation light to study properties of the Michel electron sample are presented.« less

  10. Influence of detector noise and background noise on detection-system

    NASA Astrophysics Data System (ADS)

    Song, Yiheng; Wang, Zhiyong

    2018-02-01

    Study the noise by detectors and background light ,we find that the influence of background noise on the detection is more than that of itself. Therefore, base on the fiber coupled beam splitting technique, the small area detector is used to replace the large area detector. It can achieve high signal-to-noise ratio (SNR) and reduce the speckle interference of the background light. This technique is expected to solve the bottleneck of large field of view and high sensitivity.

  11. Optic probe for semiconductor characterization

    DOEpatents

    Sopori, Bhushan L [Denver, CO; Hambarian, Artak [Yerevan, AM

    2008-09-02

    Described herein is an optical probe (120) for use in characterizing surface defects in wafers, such as semiconductor wafers. The optical probe (120) detects laser light reflected from the surface (124) of the wafer (106) within various ranges of angles. Characteristics of defects in the surface (124) of the wafer (106) are determined based on the amount of reflected laser light detected in each of the ranges of angles. Additionally, a wafer characterization system (100) is described that includes the described optical probe (120).

  12. Fiberoptic spectrophotometer

    DOEpatents

    Tans, P.P.; Lashof, D.A.

    1986-12-23

    A device is described for determining the relative composition of a sample of a gas by comparison of the Raman-scattered light of the sample with that of a known gas comprising: a means for passing a single light source through the unknown and the known gases, choppers to alternate the Raman-scattered light into a common light detection and measuring system, optical fiber networks for spatially mixing the resulting Raman scattered light from each sample and directing the mixed light to selective detectors, and a compiler to record the light intensity of each wavelength of Raman-scattered light as a function of the sample from which it originated. 6 figs.

  13. A polarization sensitive hyperspectral imaging system for detection of differences in tissue properties

    NASA Astrophysics Data System (ADS)

    Peller, Joseph A.; Ceja, Nancy K.; Wawak, Amanda J.; Trammell, Susan R.

    2018-02-01

    Polarized light imaging and optical spectroscopy can be used to distinguish between healthy and diseased tissue. In this study, the design and testing of a single-pixel hyperspectral imaging system that uses differences in the polarization of light reflected from tissue to differentiate between healthy and thermally damaged tissue is discussed. Thermal lesions were created in porcine skin (n = 8) samples using an IR laser. The damaged regions were clearly visible in the polarized light hyperspectral images. Reflectance hyperspectral and white light imaging was also obtained for all tissue samples. Sizes of the thermally damaged regions as measured via polarized light hyperspectral imaging are compared to sizes of these regions as measured in the reflectance hyperspectral images and white light images. Good agreement between the sizes measured by all three imaging modalities was found. Hyperspectral polarized light imaging can differentiate between healthy and damaged tissue. Possible applications of this imaging system include determination of tumor margins during cancer surgery or pre-surgical biopsy.

  14. Versatile light-emitting-diode-based spectral response measurement system for photovoltaic device characterization.

    PubMed

    Hamadani, Behrang H; Roller, John; Dougherty, Brian; Yoon, Howard W

    2012-07-01

    An absolute differential spectral response measurement system for solar cells is presented. The system couples an array of light emitting diodes with an optical waveguide to provide large area illumination. Two unique yet complementary measurement methods were developed and tested with the same measurement apparatus. Good agreement was observed between the two methods based on testing of a variety of solar cells. The first method is a lock-in technique that can be performed over a broad pulse frequency range. The second method is based on synchronous multifrequency optical excitation and electrical detection. An innovative scheme for providing light bias during each measurement method is discussed.

  15. The Zero-Degree Detector System for Fragmentation Studies

    NASA Technical Reports Server (NTRS)

    Adams, J. H., Jr.; Christl, M. J.; Howell, L. W.; Kuznetsov, E.

    2006-01-01

    The measurement of nuclear fragmentation cross sections requires the detection and identification of individual projectile fragments. If light and heavy fragments are recorded in 'ne same detector, it may be impossible distinguish the signal from the light fragment. To overcome this problem, we have developed the Zero-Degree Detector System. The ZDDS enables the measurement of cross sections for light fragment production by using pixelated detectors to separately measure the signals of each fragment. The system has been used to measure the fragmentation of beams as heavy as Fe at the NASA Space Radiation Laboratory at Brookhaven National Laboratory and the Heavy Ion Medical Accelerator in Chiba, Japan.

  16. Wide-field and high-resolution optical imaging for early detection of oral neoplasia

    NASA Astrophysics Data System (ADS)

    Pierce, Mark C.; Schwarz, Richard A.; Rosbach, Kelsey; Roblyer, Darren; Muldoon, Tim; Williams, Michelle D.; El-Naggar, Adel K.; Gillenwater, Ann M.; Richards-Kortum, Rebecca

    2010-02-01

    Current procedures for oral cancer screening typically involve visual inspection of the entire tissue surface at risk under white light illumination. However, pre-cancerous lesions can be difficult to distinguish from many benign conditions when viewed under these conditions. We have developed wide-field (macroscopic) imaging system which additionally images in cross-polarized white light, narrowband reflectance, and fluorescence imaging modes to reduce specular glare, enhance vascular contrast, and detect disease-related alterations in tissue autofluorescence. We have also developed a portable system to enable high-resolution (microscopic) evaluation of cellular features within the oral mucosa in situ. This system is a wide-field epi-fluorescence microscope coupled to a 1 mm diameter, flexible fiber-optic imaging bundle. Proflavine solution was used to specifically label cell nuclei, enabling the characteristic differences in N/C ratio and nuclear distribution between normal, dysplastic, and cancerous oral mucosa to be quantified. This paper discusses the technical design and performance characteristics of these complementary imaging systems. We will also present data from ongoing clinical studies aimed at evaluating diagnostic performance of these systems for detection of oral neoplasia.

  17. Iris biometric system design using multispectral imaging

    NASA Astrophysics Data System (ADS)

    Widhianto, Benedictus Yohanes Bagus Y. B.; Nasution, Aulia M. T.

    2016-11-01

    An identity recognition system is a vital component that cannot be separated from life, iris biometric is one of the biometric that has the best accuracy reaching 99%. Usually, iris biometric systems use infrared spectrum lighting to reduce discomfort caused by radiation when the eye is given direct light, while the eumelamin that is forming the iris has the most flourescent radiation when given a spectrum of visible light. This research will be conducted by detecting iris wavelengths of 850 nm, 560 nm, and 590 nm, where the detection algorithm will be using Daugman algorithm by using a Gabor wavelet extraction feature, and matching feature using a Hamming distance. Results generated will be analyzed to identify how much differences there are, and to improve the accuracy of the multispectral biometric system and as a detector of the authenticity of the iris. The results obtained from the analysis of wavelengths 850 nm, 560 nm, and 590 nm respectively has an accuracy of 99,35 , 97,5 , 64,5 with a matching score of 0,26 , 0,23 , 0,37.

  18. Detecting Negative Obstacles by Use of Radar

    NASA Technical Reports Server (NTRS)

    Mittskus, Anthony; Lux, James

    2006-01-01

    Robotic land vehicles would be equipped with small radar systems to detect negative obstacles, according to a proposal. The term "negative obstacles" denotes holes, ditches, and any other terrain features characterized by abrupt steep downslopes that could be hazardous for vehicles. Video cameras and other optically based obstacle-avoidance sensors now installed on some robotic vehicles cannot detect obstacles under adverse lighting conditions. Even under favorable lighting conditions, they cannot detect negative obstacles. A radar system according to the proposal would be of the frequency-modulation/ continuous-wave (FM/CW) type. It would be installed on a vehicle, facing forward, possibly with a downward slant of the main lobe(s) of the radar beam(s) (see figure). It would utilize one or more wavelength(s) of the order of centimeters. Because such wavelengths are comparable to the characteristic dimensions of terrain features associated with negative hazards, a significant amount of diffraction would occur at such features. In effect, the diffraction would afford a limited ability to see corners and to see around corners. Hence, the system might utilize diffraction to detect corners associated with negative obstacles. At the time of reporting the information for this article, preliminary analyses of diffraction at simple negative obstacles had been performed, but an explicit description of how the system would utilize diffraction was not available.

  19. A fiber-based quasi-continuous-wave quantum key distribution system

    PubMed Central

    Shen, Yong; Chen, Yan; Zou, Hongxin; Yuan, Jianmin

    2014-01-01

    We report a fiber-based quasi-continuous-wave (CW) quantum key distribution (QKD) system with continuous variables (CV). This system employs coherent light pulses and time multiplexing to maximally reduce cross talk in the fiber. No-switching detection scheme is adopted to optimize the repetition rate. Information is encoded on the sideband of the pulsed coherent light to fully exploit the continuous wave nature of laser field. With this configuration, high secret key rate can be achieved. For the 50 MHz detected bandwidth in our experiment, when the multidimensional reconciliation protocol is applied, a secret key rate of 187 kb/s can be achieved over 50 km of optical fiber against collective attacks, which have been shown to be asymptotically optimal. Moreover, recently studied loopholes have been fixed in our system. PMID:24691409

  20. Malaria Diagnosis Using a Mobile Phone Polarized Microscope

    NASA Astrophysics Data System (ADS)

    Pirnstill, Casey W.; Coté, Gerard L.

    2015-08-01

    Malaria remains a major global health burden, and new methods for low-cost, high-sensitivity, diagnosis are essential, particularly in remote areas with low-resource around the world. In this paper, a cost effective, optical cell-phone based transmission polarized light microscope system is presented for imaging the malaria pigment known as hemozoin. It can be difficult to determine the presence of the pigment from background and other artifacts, even for skilled microscopy technicians. The pigment is much easier to observe using polarized light microscopy. However, implementation of polarized light microscopy lacks widespread adoption because the existing commercial devices have complicated designs, require sophisticated maintenance, tend to be bulky, can be expensive, and would require re-training for existing microscopy technicians. To this end, a high fidelity and high optical resolution cell-phone based polarized light microscopy system is presented which is comparable to larger bench-top polarized microscopy systems but at much lower cost and complexity. The detection of malaria in fixed and stained blood smears is presented using both, a conventional polarized microscope and our cell-phone based system. The cell-phone based polarimetric microscopy design shows the potential to have both the resolution and specificity to detect malaria in a low-cost, easy-to-use, modular platform.

  1. Malaria Diagnosis Using a Mobile Phone Polarized Microscope

    PubMed Central

    Pirnstill, Casey W.; Coté, Gerard L.

    2015-01-01

    Malaria remains a major global health burden, and new methods for low-cost, high-sensitivity, diagnosis are essential, particularly in remote areas with low-resource around the world. In this paper, a cost effective, optical cell-phone based transmission polarized light microscope system is presented for imaging the malaria pigment known as hemozoin. It can be difficult to determine the presence of the pigment from background and other artifacts, even for skilled microscopy technicians. The pigment is much easier to observe using polarized light microscopy. However, implementation of polarized light microscopy lacks widespread adoption because the existing commercial devices have complicated designs, require sophisticated maintenance, tend to be bulky, can be expensive, and would require re-training for existing microscopy technicians. To this end, a high fidelity and high optical resolution cell-phone based polarized light microscopy system is presented which is comparable to larger bench-top polarized microscopy systems but at much lower cost and complexity. The detection of malaria in fixed and stained blood smears is presented using both, a conventional polarized microscope and our cell-phone based system. The cell-phone based polarimetric microscopy design shows the potential to have both the resolution and specificity to detect malaria in a low-cost, easy-to-use, modular platform. PMID:26303238

  2. Development of an oxygen saturation measuring system by using near-infrared spectroscopy

    NASA Astrophysics Data System (ADS)

    Kono, K.; Nakamachi, E.; Morita, Y.

    2017-08-01

    Recently, the hypoxia imaging has been recognized as the advanced technique to detect cancers because of a strong relationship with the biological characterization of cancer. In previous studies, hypoxia imaging systems for endoscopic diagnosis have been developed. However, these imaging technologies using the visible light can observe only blood vessels in gastric mucous membrane. Therefore, they could not detect scirrhous gastric cancer which accounts for 10% of all gastric cancers and spreads rapidly into submucous membrane. To overcome this problem, we developed a measuring system of blood oxygen saturation in submucous membrane by using near-infrared (NIR) spectroscopy. NIR, which has high permeability for bio-tissues and high absorbency for hemoglobin, can image and observe blood vessels in submucous membrane. NIR system with LED lights and a CCD camera module was developed to image blood vessels. We measured blood oxygen saturation using the optical density ratio (ODR) of two wavelengths, based on Lambert-Beer law. To image blood vessel clearly and measure blood oxygen saturation accurately, we searched two optimum wavelengths by using a multilayer human gastric-like phantom which has same optical properties as human gastric one. By using Monte Carlo simulation of light propagation, we derived the relationship between the ODR and blood oxygen saturation and elucidated the influence of blood vessel depth on measuring blood oxygen saturation. The oxygen saturation measuring methodology was validated with experiments using our NIR system. Finally, it was confirmed that our system can detect oxygen saturation in various depth blood vessels accurately.

  3. Biosensing of BCR/ABL fusion gene using an intensity-interrogation surface plasmon resonance imaging system

    NASA Astrophysics Data System (ADS)

    Wu, Jiangling; Huang, Yu; Bian, Xintong; Li, DanDan; Cheng, Quan; Ding, Shijia

    2016-10-01

    In this work, a custom-made intensity-interrogation surface plasmon resonance imaging (SPRi) system has been developed to directly detect a specific sequence of BCR/ABL fusion gene in chronic myelogenous leukemia (CML). The variation in the reflected light intensity detected from the sensor chip composed of gold islands array is proportional to the change of refractive index due to the selective hybridization of surface-bound DNA probes with target ssDNA. SPRi measurements were performed with different concentrations of synthetic target DNA sequence. The calibration curve of synthetic target sequence shows a good relationship between the concentration of synthetic target and the change of reflected light intensity. The detection limit of this SPRi measurement could approach 10.29 nM. By comparing SPRi images, the target ssDNA and non-complementary DNA sequence are able to be distinguished. This SPRi system has been applied for assay of BCR/ABL fusion gene extracted from real samples. This nucleic acid-based SPRi biosensor therefore offers an alternative high-effective, high-throughput label-free tool for DNA detection in biomedical research and molecular diagnosis.

  4. Field evaluation of smart sensor vehicle detectors at railroad grade crossings - volume 4 : performance in adverse weather conditions.

    DOT National Transportation Integrated Search

    2015-01-01

    The performance of a microwave radar system for vehicle detection at a railroad grade crossing with quadrant gates was evaluated in : adverse weather conditions: rain (light and torrential), snow (light and heavy), dense fog, and wind. The first part...

  5. Microscopy imaging system and method employing stimulated raman spectroscopy as a contrast mechanism

    DOEpatents

    Xie, Xiaoliang Sunney [Lexington, MA; Freudiger, Christian [Boston, MA; Min, Wei [Cambridge, MA

    2011-09-27

    A microscopy imaging system includes a first light source for providing a first train of pulses at a first center optical frequency .omega..sub.1, a second light source for providing a second train of pulses at a second center optical frequency .omega..sub.2, a modulator system, an optical detector, and a processor. The modulator system is for modulating a beam property of the second train of pulses at a modulation frequency f of at least 100 kHz. The optical detector is for detecting an integrated intensity of substantially all optical frequency components of the first train of pulses from the common focal volume by blocking the second train of pulses being modulated. The processor is for detecting, a modulation at the modulation frequency f, of the integrated intensity of the optical frequency components of the first train of pulses to provide a pixel of an image for the microscopy imaging system.

  6. Detection of ICG at low concentrations by photoacoustic imaging system using LED light source

    NASA Astrophysics Data System (ADS)

    Shigeta, Yusuke; Agano, Toshitaka; Sato, Naoto; Nakatsuka, Hitoshi; Kitagawa, Kazuo; Hanaoka, Takamitsu; Morisono, Koji; Tanaka, Chizuyo

    2017-03-01

    Recently, various type of photoacoustic imaging (PAI) that can visualize properties and distribution of light absorber have been researched. We developed PAI system using LED light source and evaluated characteristics of photoacoustic signal intensity versus Indocyanine Green (ICG) concentration. In this experiment, a linear type PZT array transducer (128-elements, 10.0MHz center frequency) was used to be able to transmit and receive ultrasound and also detect photoacoustic signal from the target object. The transducer was connected to the PAI system, and two sets of LED light source that had 850nm wavelength chip array were set to the both side of the transducer. The transducer head was placed at a distance of 20 mm from the target in the water bath. The target object was a tube filled with ICG in it. The tubes containing ICG at concentrations from 300nanomolar to 3millimolar were made by diluting original ICG solution. We measured the photoacoustic signal strength from RF signal generated from the ICG in the tube, and the results showed that the intensity of the signal was almost linear response to the concentration in log-log scale.

  7. Use of near-infrared video recording system for the detection of freeze damaged citrus leaves

    NASA Technical Reports Server (NTRS)

    Escobar, D. E.; Bowen, R. L.; Gausman, H. W.; Cooper, G. (Principal Investigator)

    1982-01-01

    A video recording system with a visible light blocking filter to give sensitivity in the 0.78 m to 1.1 m waveband detected freeze-damaged citrus leaves rapidly. With this technique, the time to analyze images can be decreased from about one day for conventional photography to less than one hour for video recording.

  8. Cell sorting using efficient light shaping approaches

    NASA Astrophysics Data System (ADS)

    Bañas, Andrew; Palima, Darwin; Villangca, Mark; Glückstad, Jesper

    2016-03-01

    Early detection of diseases can save lives. Hence, there is emphasis in sorting rare disease-indicating cells within small dilute quantities such as in the confines of lab-on-a-chip devices. In our work, we use optical forces to isolate red blood cells detected by machine vision. This approach is gentler, less invasive and more economical compared to conventional FACS systems. As cells are less responsive to plastic or glass beads commonly used in the optical manipulation literature, and since laser safety would be an issue in clinical use, we develop efficient approaches in utilizing lasers and light modulation devices. The Generalized Phase Contrast (GPC) method that can be used for efficiently illuminating spatial light modulators or creating well-defined contiguous optical traps is supplemented by diffractive techniques capable of integrating the available light and creating 2D or 3D beam distributions aimed at the positions of the detected cells. Furthermore, the beam shaping freedom provided by GPC can allow optimizations in the beam's propagation and its interaction with the catapulted cells.

  9. Visualization of retinal vascular structure and perfusion with a nonconfocal adaptive optics scanning light ophthalmoscope

    PubMed Central

    Sulai, Yusufu N.; Scoles, Drew; Harvey, Zachary; Dubra, Alfredo

    2015-01-01

    Imaging of the retinal vascular structure and perfusion was explored by confocal illumination and nonconfocal detection in an adaptive optics scanning light ophthalmoscope (AOSLO), as an extension of the work by Chui et al. [Biomed. Opt. Express 3, 2537 (2012)]. Five different detection schemes were evaluated at multiple retinal locations: circular mask, annular mask, circular mask with filament, knife-edge, and split-detector. Given the superior image contrast in the reflectance and perfusion maps, the split-detection method was further tested using pupil apodization, polarized detection, and four different wavelengths. None of these variations provided noticeable contrast improvement. The noninvasive visualization of capillary flow and structure provided by AOSLO split-detection shows great promise for studying ocular and systemic conditions that affect the retinal vasculature. PMID:24690655

  10. Integrated High Resolution Digital Color Light Sensor in 130 nm CMOS Technology.

    PubMed

    Strle, Drago; Nahtigal, Uroš; Batistell, Graciele; Zhang, Vincent Chi; Ofner, Erwin; Fant, Andrea; Sturm, Johannes

    2015-07-22

    This article presents a color light detection system integrated in 130 nm CMOS technology. The sensors and corresponding electronics detect light in a CIE XYZ color luminosity space using on-chip integrated sensors without any additional process steps, high-resolution analog-to-digital converter, and dedicated DSP algorithm. The sensor consists of a set of laterally arranged integrated photodiodes that are partly covered by metal, where color separation between the photodiodes is achieved by lateral carrier diffusion together with wavelength-dependent absorption. A high resolution, hybrid, ∑∆ ADC converts each photo diode's current into a 22-bit digital result, canceling the dark current of the photo diodes. The digital results are further processed by the DSP, which calculates normalized XYZ or RGB color and intensity parameters using linear transformations of the three photo diode responses by multiplication of the data with a transformation matrix, where the coefficients are extracted by training in combination with a pseudo-inverse operation and the least-mean square approximation. The sensor system detects the color light parameters with 22-bit accuracy, consumes less than 60 μA on average at 10 readings per second, and occupies approx. 0.8 mm(2) of silicon area (including three photodiodes and the analog part of the ADC). The DSP is currently implemented on FPGA.

  11. Headlamps for light based driver assistance

    NASA Astrophysics Data System (ADS)

    Götz, M.; Kleinkes, M.

    2008-04-01

    Driving at night is dangerous. Although only 25% of all driving tasks are performed at night, nearly half of all fatal accidents happen in this time. In order to increase safety when driving under poor visibility conditions, automotive front lighting systems have undergone a strong development in the last fifteen years. One important milestone was the introduction of Xenon headlamps in 1992, which provide more and brighter light for road illumination than ever before. Since then the paradigm of simply providing more light has changed toward providing optimised light distributions, which support the driver's perception. A first step in this direction was the introduction of dynamic bend lighting and cornering light in 2003. In 2006 the first full AFS headlamp (Adaptive Front Lighting System) allowed an optimised adoption of the light distribution to the driving situation. These systems use information provided by vehicle sensors and an intelligent algorithm to guide light towards those areas where needed. Nowadays, even more information about the vehicle's environment is available. Image processing systems, for example, allow to detect other traffic participants, their speed and their driving directions. In future headlamp systems these data will be used to constantly regulate the reach of the light distribution thus allowing a maximal reach without providing glare. Moreover, technologies that allow to constantly use a high-beam light distribution are under development. These systems will illuminate the whole traffic area only excluding other traffic participants. LED light sources will play a significant role in these scenarios, since they allow to precisely illuminate certain areas of the road, while neighbouring parts will be left in dark.

  12. Micro spectrometer for parallel light and method of use

    NASA Technical Reports Server (NTRS)

    Park, Yeonjoon (Inventor); Choi, Sang H. (Inventor); King, Glen C. (Inventor); Elliott, James R. (Inventor)

    2011-01-01

    A spectrometer system includes an optical assembly for collimating light, a micro-ring grating assembly having a plurality of coaxially-aligned ring gratings, an aperture device defining an aperture circumscribing a target focal point, and a photon detector. An electro-optical layer of the grating assembly may be electrically connected to an energy supply to change the refractive index of the electro-optical layer. Alternately, the gratings may be electrically connected to the energy supply and energized, e.g., with alternating voltages, to change the refractive index. A data recorder may record the predetermined spectral characteristic. A method of detecting a spectral characteristic of a predetermined wavelength of source light includes generating collimated light using an optical assembly, directing the collimated light onto the micro-ring grating assembly, and selectively energizing the micro-ring grating assembly to diffract the predetermined wavelength onto the target focal point, and detecting the spectral characteristic using a photon detector.

  13. Laser Illumination Modality of Photoacoustic Imaging Technique for Prostate Cancer

    NASA Astrophysics Data System (ADS)

    Peng, Dong-qing; Peng, Yuan-yuan; Guo, Jian; Li, Hui

    2016-02-01

    Photoacoustic imaging (PAI) has recently emerged as a promising imaging technique for prostate cancer. But there was still a lot of challenge in the PAI for prostate cancer detection, such as laser illumination modality. Knowledge of absorbed light distribution in prostate tissue was essential since the distribution characteristic of absorbed light energy would influence the imaging depth and range of PAI. In order to make a comparison of different laser illumination modality of photoacoustic imaging technique for prostate cancer, optical model of human prostate was established and combined with Monte Carlo simulation method to calculate the light absorption distribution in the prostate tissue. Characteristic of light absorption distribution of transurethral and trans-rectal illumination case, and of tumor at different location was compared with each other.The relevant conclusions would be significant for optimizing the light illumination in a PAI system for prostate cancer detection.

  14. Integrated optical biosensor system (IOBS)

    DOEpatents

    Grace, Karen M.; Sweet, Martin R.; Goeller, Roy M.; Morrison, Leland Jean; Grace, Wynne Kevin; Kolar, Jerome D.

    2007-10-30

    An optical biosensor has a first enclosure with a pathogen recognition surface, including a planar optical waveguide and grating located in the first enclosure. An aperture is in the first enclosure for insertion of sample to be investigated to a position in close proximity to the pathogen recognition surface. A laser in the first enclosure includes means for aligning and means for modulating the laser, the laser having its light output directed toward said grating. Detection means are located in the first enclosure and in optical communication with the pathogen recognition surface for detecting pathogens after interrogation by the laser light and outputting the detection. Electronic means is located in the first enclosure and receives the detection for processing the detection and outputting information on the detection, and an electrical power supply is located in the first enclosure for supplying power to the laser, the detection means and the electronic means.

  15. Radar Based Navigation in Unknown Terrain

    DTIC Science & Technology

    2012-12-31

    localization and mapping ( SLAM ) approach. The radar processing algorithms detect strong, persistent, and stationary reflectors embedded in the...Global System for Mobile Communications . . . . . . . . . 2 LIDAR Light Detection and Ranging . . . . . . . . . . . . . . . . 2 SAR Synthetic Aperture...22 SLAM Simultaneous Localization and Mapping . . . . . . . . . . 25 FDM Frequency Division Multiplexing

  16. A homogeneous biochemiluminescent assay for detection of influenza

    NASA Astrophysics Data System (ADS)

    Hui, Kwok Min; Li, Xiao Jing; Pan, Lu; Li, X. J.

    2015-05-01

    Current methods of rapid detection of influenza are based on detection of the nucleic acids or antigens of influenza viruses. Since influenza viruses constantly mutate leading to appearance of new strains or variants of viruses, these detection methods are susceptible to genetic changes in influenza viruses. Type A and B influenza viruses contain neuraminidase, an essential enzyme for virus replication which enables progeny influenza viruses leave the host cells to infect new cells. Here we describe an assay method, the homogeneous biochemiluminescent assay (HBA), for rapid detection of influenza by detecting viral neuraminidase activity. The assay mimics the light production process of a firefly: a viral neuraminidase specific substrate containing a luciferin moiety is cleaved in the presence of influenza virus to release luciferin, which becomes a substrate to firefly luciferase in a light production system. All reagents can be formulated in a single reaction mix so that the assay involves only one manual step, i.e., sample addition. Presence of Type A or B influenza virus in the sample leads to production of strong, stable and easily detectable light signal, which lasts for hours. Thus, this influenza virus assay is suitable for use in point-of-care settings.

  17. Direct and sensitive detection of foodborne pathogens within fresh produce samples using a field-deployable handheld device.

    PubMed

    You, David J; Geshell, Kenneth J; Yoon, Jeong-Yeol

    2011-10-15

    Direct and sensitive detection of foodborne pathogens from fresh produce samples was accomplished using a handheld lab-on-a-chip device, requiring little to no sample processing and enrichment steps for a near-real-time detection and truly field-deployable device. The detection of Escherichia coli K12 and O157:H7 in iceberg lettuce was achieved utilizing optimized Mie light scatter parameters with a latex particle immunoagglutination assay. The system exhibited good sensitivity, with a limit of detection of 10 CFU mL(-1) and an assay time of <6 min. Minimal pretreatment with no detrimental effects on assay sensitivity and reproducibility was accomplished with a simple and cost-effective KimWipes filter and disposable syringe. Mie simulations were used to determine the optimal parameters (particle size d, wavelength λ, and scatter angle θ) for the assay that maximize light scatter intensity of agglutinated latex microparticles and minimize light scatter intensity of the tissue fragments of iceberg lettuce, which were experimentally validated. This introduces a powerful method for detecting foodborne pathogens in fresh produce and other potential sample matrices. The integration of a multi-channel microfluidic chip allowed for differential detection of the agglutinated particles in the presence of the antigen, revealing a true field-deployable detection system with decreased assay time and improved robustness over comparable benchtop systems. Additionally, two sample preparation methods were evaluated through simulated field studies based on overall sensitivity, protocol complexity, and assay time. Preparation of the plant tissue sample by grinding resulted in a two-fold improvement in scatter intensity over washing, accompanied with a significant increase in assay time: ∼5 min (grinding) versus ∼1 min (washing). Specificity studies demonstrated binding of E. coli O157:H7 EDL933 to only O157:H7 antibody conjugated particles, with no cross-reactivity to K12. This suggests the adaptability of the system for use with a wide variety of pathogens, and the potential to detect in a variety of biological matrices with little to no sample pretreatment. Copyright © 2011 Elsevier B.V. All rights reserved.

  18. Multi-dimensional spatial light communication made with on-chip InGaN photonic integration

    NASA Astrophysics Data System (ADS)

    Yang, Yongchao; Zhu, Bingcheng; Shi, Zheng; Wang, Jinyuan; Li, Xin; Gao, Xumin; Yuan, Jialei; Li, Yuanhang; Jiang, Yan; Wang, Yongjin

    2017-04-01

    Here, we propose, fabricate and characterize suspended photonic integration of InGaN multiple-quantum-well light-emitting diode (MQW-LED), waveguide and InGaN MQW-photodetector on a single chip. The unique light emission property of InGaN MQW-LED makes it feasible to establish multi-dimensional spatial data transmission using visible light. The in-plane light communication system is comprised of InGaN MQW-LED, waveguide and InGaN MQW-photodetector, and the out-of-plane data transmission is realized by detecting the free-space light emission via a commercial photodiode module. Moreover, a full-duplex light communication is experimentally demonstrated at a data transmission rate of 50 Mbps when both InGaN MQW-diodes operate under simultaneous light emission and detection mode. The in-plane superimposed signals are able to be extracted through the self-interference cancellation method, and the out-of-plane superimposed signals are in good agreement with the calculated signals according to the extracted transmitted signals. These results are promising for the development of on-chip InGaN photonic integration for diverse applications.

  19. Superchiral Light Generation on Degenerate Achiral Surfaces

    NASA Astrophysics Data System (ADS)

    Vázquez-Guardado, Abraham; Chanda, Debashis

    2018-03-01

    A novel route of superchiral near-field generation is demonstrated based on geometrically achiral systems supporting degenerate and spatially superimposed plasmonic modes. Such systems generate a single-handed chiral near field with simultaneous zero far-field circular dichroism. The phenomenon is theoretically elucidated with a rotating dipole model, which predicts a uniform single-handed chiral near field that flips handedness solely by reversing the handedness of the source. This property allows detection of pure background free molecular chirality through near-field light-matter interaction, which is experimentally demonstrated in the precise identification of both handedness of a chiral molecule on a single substrate with about four orders of magnitude enhancement in detection sensitivity compared to its conventional volumetric counterpart.

  20. System for characterizing semiconductor materials and photovoltaic device

    DOEpatents

    Sopori, B.L.

    1996-12-03

    Apparatus for detecting and mapping defects in the surfaces of polycrystalline material in a manner that distinguishes dislocation pits from grain boundaries includes a first laser of a first wavelength for illuminating a wide spot on the surface of the material, a second laser of a second relatively shorter wavelength for illuminating a relatively narrower spot on the surface of the material, a light integrating sphere with apertures for capturing light scattered by etched dislocation pits in an intermediate range away from specular reflection while allowing light scattered by etched grain boundaries in a near range from specular reflection to pass through, and optical detection devices for detecting and measuring intensities of the respective intermediate scattered light and near specular scattered light. A center blocking aperture or filter can be used to screen out specular reflected light, which would be reflected by nondefect portions of the polycrystalline material surface. An X-Y translation stage for mounting the polycrystalline material and signal processing and computer equipment accommodate raster mapping, recording, and displaying of respective dislocation and grain boundary defect densities. A special etch procedure is included, which prepares the polycrystalline material surface to produce distinguishable intermediate and near specular light scattering in patterns that have statistical relevance to the dislocation and grain boundary defect densities. A reflectance measurement of the piece of material is obtained by adding together the signals from the optical detection devices. In the case where the piece of material includes a photovoltaic device, the current induced in the device by the illuminating light can be measured with a current sensing amplifier after the light integrating sphere is moved away from the device. 22 figs.

  1. An LED light source and novel fluorophore combinations improve fluorescence laparoscopic detection of metastatic pancreatic cancer in orthotopic mouse models.

    PubMed

    Metildi, Cristina A; Kaushal, Sharmeela; Lee, Claudia; Hardamon, Chanae R; Snyder, Cynthia S; Luiken, George A; Talamini, Mark A; Hoffman, Robert M; Bouvet, Michael

    2012-06-01

    The aim of this study was to improve fluorescence laparoscopy of pancreatic cancer in an orthotopic mouse model with the use of a light-emitting diode (LED) light source and optimal fluorophore combinations. Human pancreatic cancer models were established with fluorescent FG-RFP, MiaPaca2-GFP, BxPC-3-RFP, and BxPC-3 cancer cells implanted in 6-week-old female athymic mice. Two weeks postimplantation, diagnostic laparoscopy was performed with a Stryker L9000 LED light source or a Stryker X8000 xenon light source 24 hours after tail-vein injection of CEA antibodies conjugated with Alexa 488 or Alexa 555. Cancer lesions were detected and localized under each light mode. Intravital images were also obtained with the OV-100 Olympus and Maestro CRI Small Animal Imaging Systems, serving as a positive control. Tumors were collected for histologic analysis. Fluorescence laparoscopy with a 495-nm emission filter and an LED light source enabled real-time visualization of the fluorescence-labeled tumor deposits in the peritoneal cavity. The simultaneous use of different fluorophores (Alexa 488 and Alexa 555), conjugated to antibodies, brightened the fluorescence signal, enhancing detection of submillimeter lesions without compromising background illumination. Adjustments to the LED light source permitted simultaneous detection of tumor lesions of different fluorescent colors and surrounding structures with minimal autofluorescence. Using an LED light source with adjustments to the red, blue, and green wavelengths, it is possible to simultaneously identify tumor metastases expressing fluorescent proteins of different wavelengths, which greatly enhanced the signal without compromising background illumination. Development of this fluorescence laparoscopy technology for clinical use can improve staging and resection of pancreatic cancer. Copyright © 2012 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

  2. System for characterizing semiconductor materials and photovoltaic device

    DOEpatents

    Sopori, Bhushan L.

    1996-01-01

    Apparatus for detecting and mapping defects in the surfaces of polycrystalline material in a manner that distinguishes dislocation pits from grain boundaries includes a first laser of a first wavelength for illuminating a wide spot on the surface of the material, a second laser of a second relatively shorter wavelength for illuminating a relatively narrower spot on the surface of the material, a light integrating sphere with apertures for capturing light scattered by etched dislocation pits in an intermediate range away from specular reflection while allowing light scattered by etched grain boundaries in a near range from specular reflection to pass through, and optical detection devices for detecting and measuring intensities of the respective intermediate scattered light and near specular scattered light. A center blocking aperture or filter can be used to screen out specular reflected light, which would be reflected by nondefect portions of the polycrystalline material surface. An X-Y translation stage for mounting the polycrystalline material and signal processing and computer equipment accommodate raster mapping, recording, and displaying of respective dislocation and grain boundary defect densities. A special etch procedure is included, which prepares the polycrystalline material surface to produce distinguishable intermediate and near specular light scattering in patterns that have statistical relevance to the dislocation and grain boundary defect densities. A reflectance measurement of the piece of material is obtained by adding together the signals from the optical detection devices. In the case where the piece of material includes a photovoltaic device, the current induced in the device by the illuminating light can be measured with a current sensing amplifier after the light integrating sphere is moved away from the device.

  3. Scattered Light Polarimetry of Exoplanets

    NASA Astrophysics Data System (ADS)

    Wiktorowicz, S.

    2014-12-01

    The last decade has witnessed an explosion in atmospheric characterization of spatially unresolved exoplanets using transmission spectra of transiting planets, but understanding has been hampered by degeneracies resolvable through blue optical observations. Here, scattered light is more important than the Wien tail of re-radiated thermal emission. Therefore, the next frontier in exoplanet characterization lies in the direct detection of scattered light. The polarization state of starlight scattered by a planetary atmosphere distinguishes it from the direct light from the host star, and the inherently differential nature of polarimetry reduces systematic effects to the point where ground-based detections are possible. Furthermore, polarimetry is uniquely sensitive to the size distribution, shape, and chemical composition of atmospheric cloud particles as well as to the scattering optical depth. I will review the current state of exoplanet polarimetry, which is dominated not by photon noise but by non-Gaussian systematic effects. Ground-based detection of order ten exoplanet photons relative to the host star's million requires dense orbital phase coverage and therefore long observing programs. However, variability inherent in the host star, interstellar medium, Earth's atmosphere, the telescope, and the instrument at all timescales must be measured and subtracted in order to definitively uncover scattered light from the exoplanet. While polarimetry is in principle sensitive to exoplanets regardless of orbital inclination, repeated observations of transiting exoplanet systems during secondary eclipse events are required to measure the polarimetric variability of the system that cannot be due to the planet. The emergence of scattered light polarimetry as a robust tool for the study of exoplanet atmospheres, and eventually surfaces, therefore requires diligent attention to the role of systematic effects.

  4. System and method for measuring particles in a sample stream of a flow cytometer using a low power laser source

    DOEpatents

    Graves, Steven W; Habbersett, Robert C

    2013-10-22

    A system and method for analyzing a particle in a sample stream of a flow cytometer or the like. The system has a light source, such as a laser pointer module, for generating a low powered light beam and a fluidics apparatus which is configured to transport particles in the sample stream at substantially low velocity through the light beam for interrogation. Detectors, such as photomultiplier tubes, are configured to detect optical signals generated in response to the light beam impinging the particles. Signal conditioning circuitry is connected to each of the detectors to condition each detector output into electronic signals for processing and is designed to have a limited frequency response to filter high frequency noise from the detector output signals.

  5. System and method for measuring particles in a sample stream of a flow cytometer using low-power laser source

    DOEpatents

    Graves, Steven W.; Habbersett, Robert C.

    2014-07-01

    A system and method for analyzing a particle in a sample stream of a flow cytometer or the like. The system has a light source, such as a laser pointer module, for generating a low powered light beam and a fluidics apparatus which is configured to transport particles in the sample stream at substantially low velocity through the light beam for interrogation. Detectors, such as photomultiplier tubes, are configured to detect optical signals generated in response to the light beam impinging the particles. Signal conditioning circuitry is connected to each of the detectors to condition each detector output into electronic signals for processing and is designed to have a limited frequency response to filter high frequency noise from the detector output signals.

  6. System and method for measuring particles in a sample stream of a flow cytometer or the like

    DOEpatents

    Graves, Steven W.; Habberset, Robert C.

    2010-11-16

    A system and method for analyzing a particle in a sample stream of a flow cytometer or the like. The system has a light source, such as a laser pointer module, for generating a low powered light beam and a fluidics apparatus which is configured to transport particles in the sample stream at substantially low velocity through the light beam for interrogation. Detectors, such as photomultiplier tubes, are configured to detect optical signals generated in response to the light beam impinging the particles. Signal conditioning circuitry is connected to each of the detectors to condition each detector output into electronic signals for processing and is designed to have a limited frequency response to filter high frequency noise from the detector output signals.

  7. System and method for measuring particles in a sample stream of a flow cytometer using low-power laser source

    DOEpatents

    Graves, Steven W.; Habbersett, Robert C.

    2016-11-15

    A system and method for analyzing a particle in a sample stream of a flow cytometer or the like. The system has a light source, such as a laser pointer module, for generating a low powered light beam and a fluidics apparatus which is configured to transport particles in the sample stream at substantially low velocity through the light beam for interrogation. Detectors, such as photomultiplier tubes, are configured to detect optical signals generated in response to the light beam impinging the particles. Signal conditioning circuitry is connected to each of the detectors to condition each detector output into electronic signals for processing and is designed to have a limited frequency response to filter high frequency noise from the detector output signals.

  8. A DAQ-Device-Based Continuous Wave Near-Infrared Spectroscopy System for Measuring Human Functional Brain Activity

    PubMed Central

    Li, Xiaoli; Liu, Xiaomin

    2014-01-01

    In the last two decades, functional near-infrared spectroscopy (fNIRS) is getting more and more popular as a neuroimaging technique. The fNIRS instrument can be used to measure local hemodynamic response, which indirectly reflects the functional neural activities in human brain. In this study, an easily implemented way to establish DAQ-device-based fNIRS system was proposed. Basic instrumentation components (light sources driving, signal conditioning, sensors, and optical fiber) of the fNIRS system were described. The digital in-phase and quadrature demodulation method was applied in LabVIEW software to distinguish light sources from different emitters. The effectiveness of the custom-made system was verified by simultaneous measurement with a commercial instrument ETG-4000 during Valsalva maneuver experiment. The light intensity data acquired from two systems were highly correlated for lower wavelength (Pearson's correlation coefficient r = 0.92, P < 0.01) and higher wavelength (r = 0.84, P < 0.01). Further, another mental arithmetic experiment was implemented to detect neural activation in the prefrontal cortex. For 9 participants, significant cerebral activation was detected in 6 subjects (P < 0.05) for oxyhemoglobin and in 8 subjects (P < 0.01) for deoxyhemoglobin. PMID:25180044

  9. Expanding the detection efficiency of silicon drift detectors

    NASA Astrophysics Data System (ADS)

    Schlosser, D. M.; Lechner, P.; Lutz, G.; Niculae, A.; Soltau, H.; Strüder, L.; Eckhardt, R.; Hermenau, K.; Schaller, G.; Schopper, F.; Jaritschin, O.; Liebel, A.; Simsek, A.; Fiorini, C.; Longoni, A.

    2010-12-01

    To expand the detection efficiency Silicon Drift Detectors (SDDs) with various customized radiation entrance windows, optimized detector areas and geometries have been developed. Optimum values for energy resolution, peak to background ratio (P/B) and high count rate capability support the development. Detailed results on sensors optimized for light element detection down to Boron or even lower will be reported. New developments for detecting medium and high X-ray energies by increasing the effective detector thickness will be presented. Gamma-ray detectors consisting of a SDD coupled to scintillators like CsI(Tl) and LaBr 3(Ce) have been examined. Results of the energy resolution for the 137Cs 662 keV line and the light yield (LY) of such detector systems will be reported.

  10. Interferometric apparatus for ultra-high precision displacement measurement

    NASA Technical Reports Server (NTRS)

    Zhao, Feng (Inventor)

    2004-01-01

    A high-precision heterodyne interferometer measures relative displacement by creating a thermally-insensitive system generally not subject to polarization leakage. By using first and second light beams separated by a small frequency difference (.DELTA.f), beams of light at the first frequency (f.sub.0) are reflected by co-axial mirrors, the first mirror of which has a central aperture through which the light is transmitted to and reflected by the second mirror. Prior to detection, the light beams from the two mirrors are combined with light of the second and slightly different frequency. The combined light beams are separated according to the light from the mirrors. The change in phase (.DELTA..phi.) with respect to the two signals is proportional to the change in distance of Fiducial B by a factor of wavelength (.lambda.) divided by 4.pi. (.DELTA.L=.lambda..DELTA..phi.1/(4.pi.)). In a second embodiment, a polarizing beam splitting system can be used.

  11. Global Positioning System Synchronized Active Light Autonomous Docking System

    NASA Technical Reports Server (NTRS)

    Howard, Richard T. (Inventor); Book, Michael L. (Inventor); Bryan, Thomas C. (Inventor); Bell, Joseph L. (Inventor)

    1996-01-01

    A Global Positioning System Synchronized Active Light Autonomous Docking System (GPSSALADS) for automatically docking a chase vehicle with a target vehicle comprising at least one active light emitting target which is operatively attached to the target vehicle. The target includes a three-dimensional array of concomitantly flashing lights which flash at a controlled common frequency. The GPSSALADS further comprises a visual tracking sensor operatively attached to the chase vehicle for detecting and tracking the target vehicle. Its performance is synchronized with the flash frequency of the lights by a synchronization means which is comprised of first and second internal clocks operatively connected to the active light target and visual tracking sensor, respectively, for providing timing control signals thereto, respectively. The synchronization means further includes first and second Global Positioning System receivers operatively connected to the first and second internal clocks, respectively, for repeatedly providing simultaneous synchronization pulses to the internal clocks, respectively. In addition, the GPSSALADS includes a docking process controller means which is operatively attached to the chase vehicle and is responsive to the visual tracking sensor for producing commands for the guidance and propulsion system of the chase vehicle.

  12. Global Positioning System Synchronized Active Light Autonomous Docking System

    NASA Technical Reports Server (NTRS)

    Howard, Richard (Inventor)

    1994-01-01

    A Global Positioning System Synchronized Active Light Autonomous Docking System (GPSSALADS) for automatically docking a chase vehicle with a target vehicle comprises at least one active light emitting target which is operatively attached to the target vehicle. The target includes a three-dimensional array of concomitantly flashing lights which flash at a controlled common frequency. The GPSSALADS further comprises a visual tracking sensor operatively attached to the chase vehicle for detecting and tracking the target vehicle. Its performance is synchronized with the flash frequency of the lights by a synchronization means which is comprised of first and second internal clocks operatively connected to the active light target and visual tracking sensor, respectively, for providing timing control signals thereto, respectively. The synchronization means further includes first and second Global Positioning System receivers operatively connected to the first and second internal clocks, respectively, for repeatedly providing simultaneous synchronization pulses to the internal clocks, respectively. In addition, the GPSSALADS includes a docking process controller means which is operatively attached to the chase vehicle and is responsive to the visual tracking sensor for producing commands for the guidance and propulsion system of the chase vehicle.

  13. Space telescope low scattered light camera - A model

    NASA Technical Reports Server (NTRS)

    Breckinridge, J. B.; Kuper, T. G.; Shack, R. V.

    1982-01-01

    A design approach for a camera to be used with the space telescope is given. Camera optics relay the system pupil onto an annular Gaussian ring apodizing mask to control scattered light. One and two dimensional models of ripple on the primary mirror were calculated. Scattered light calculations using ripple amplitudes between wavelength/20 wavelength/200 with spatial correlations of the ripple across the primary mirror between 0.2 and 2.0 centimeters indicate that the detection of an object a billion times fainter than a bright source in the field is possible. Detection of a Jovian type planet in orbit about alpha Centauri with a camera on the space telescope may be possible.

  14. Advanced power system protection and incipient fault detection and protection of spaceborne power systems

    NASA Technical Reports Server (NTRS)

    Russell, B. Don

    1989-01-01

    This research concentrated on the application of advanced signal processing, expert system, and digital technologies for the detection and control of low grade, incipient faults on spaceborne power systems. The researchers have considerable experience in the application of advanced digital technologies and the protection of terrestrial power systems. This experience was used in the current contracts to develop new approaches for protecting the electrical distribution system in spaceborne applications. The project was divided into three distinct areas: (1) investigate the applicability of fault detection algorithms developed for terrestrial power systems to the detection of faults in spaceborne systems; (2) investigate the digital hardware and architectures required to monitor and control spaceborne power systems with full capability to implement new detection and diagnostic algorithms; and (3) develop a real-time expert operating system for implementing diagnostic and protection algorithms. Significant progress has been made in each of the above areas. Several terrestrial fault detection algorithms were modified to better adapt to spaceborne power system environments. Several digital architectures were developed and evaluated in light of the fault detection algorithms.

  15. Design of an explosive detection system using Monte Carlo method.

    PubMed

    Hernández-Adame, Pablo Luis; Medina-Castro, Diego; Rodriguez-Ibarra, Johanna Lizbeth; Salas-Luevano, Miguel Angel; Vega-Carrillo, Hector Rene

    2016-11-01

    Regardless the motivation terrorism is the most important risk for the national security in many countries. Attacks with explosives are the most common method used by terrorists. Therefore several procedures to detect explosives are utilized; among these methods are the use of neutrons and photons. In this study the Monte Carlo method an explosive detection system using a 241 AmBe neutron source was designed. In the design light water, paraffin, polyethylene, and graphite were used as moderators. In the work the explosive RDX was used and the induced gamma rays due to neutron capture in the explosive was estimated using NaI(Tl) and HPGe detectors. When light water is used as moderator and HPGe as the detector the system has the best performance allowing distinguishing between the explosive and urea. For the final design the Ambient dose equivalent for neutrons and photons were estimated along the radial and axial axis. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. Enhanced optical coupling and Raman scattering via microscopic interface engineering

    NASA Astrophysics Data System (ADS)

    Thompson, Jonathan V.; Hokr, Brett H.; Kim, Wihan; Ballmann, Charles W.; Applegate, Brian E.; Jo, Javier A.; Yamilov, Alexey; Cao, Hui; Scully, Marlan O.; Yakovlev, Vladislav V.

    2017-11-01

    Spontaneous Raman scattering is an extremely powerful tool for the remote detection and identification of various chemical materials. However, when those materials are contained within strongly scattering or turbid media, as is the case in many biological and security related systems, the sensitivity and range of Raman signal generation and detection is severely limited. Here, we demonstrate that through microscopic engineering of the optical interface, the optical coupling of light into a turbid material can be substantially enhanced. This improved coupling facilitates the enhancement of the Raman scattering signal generated by molecules within the medium. In particular, we detect at least two-orders of magnitude more spontaneous Raman scattering from a sample when the pump laser light is focused into a microscopic hole in the surface of the sample. Because this approach enhances both the interaction time and interaction region of the laser light within the material, its use will greatly improve the range and sensitivity of many spectroscopic techniques, including Raman scattering and fluorescence emission detection, inside highly scattering environments.

  17. Single photon detection and signal analysis for high sensitivity dosimetry based on optically stimulated luminescence with beryllium oxide

    NASA Astrophysics Data System (ADS)

    Radtke, J.; Sponner, J.; Jakobi, C.; Schneider, J.; Sommer, M.; Teichmann, T.; Ullrich, W.; Henniger, J.; Kormoll, T.

    2018-01-01

    Single photon detection applied to optically stimulated luminescence (OSL) dosimetry is a promising approach due to the low level of luminescence light and the known statistical behavior of single photon events. Time resolved detection allows to apply a variety of different and independent data analysis methods. Furthermore, using amplitude modulated stimulation impresses time- and frequency information into the OSL light and therefore allows for additional means of analysis. Considering the impressed frequency information, data analysis by using Fourier transform algorithms or other digital filters can be used for separating the OSL signal from unwanted light or events generated by other phenomena. This potentially lowers the detection limits of low dose measurements and might improve the reproducibility and stability of obtained data. In this work, an OSL system based on a single photon detector, a fast and accurate stimulation unit and an FPGA is presented. Different analysis algorithms which are applied to the single photon data are discussed.

  18. A Probability-Based Algorithm Using Image Sensors to Track the LED in a Vehicle Visible Light Communication System.

    PubMed

    Huynh, Phat; Do, Trong-Hop; Yoo, Myungsik

    2017-02-10

    This paper proposes a probability-based algorithm to track the LED in vehicle visible light communication systems using a camera. In this system, the transmitters are the vehicles' front and rear LED lights. The receivers are high speed cameras that take a series of images of the LEDs. ThedataembeddedinthelightisextractedbyfirstdetectingthepositionoftheLEDsintheseimages. Traditionally, LEDs are detected according to pixel intensity. However, when the vehicle is moving, motion blur occurs in the LED images, making it difficult to detect the LEDs. Particularly at high speeds, some frames are blurred at a high degree, which makes it impossible to detect the LED as well as extract the information embedded in these frames. The proposed algorithm relies not only on the pixel intensity, but also on the optical flow of the LEDs and on statistical information obtained from previous frames. Based on this information, the conditional probability that a pixel belongs to a LED is calculated. Then, the position of LED is determined based on this probability. To verify the suitability of the proposed algorithm, simulations are conducted by considering the incidents that can happen in a real-world situation, including a change in the position of the LEDs at each frame, as well as motion blur due to the vehicle speed.

  19. Evaluation of selective control information detection scheme in orthogonal frequency division multiplexing-based radio-over-fiber and visible light communication links

    NASA Astrophysics Data System (ADS)

    Dalarmelina, Carlos A.; Adegbite, Saheed A.; Pereira, Esequiel da V.; Nunes, Reginaldo B.; Rocha, Helder R. O.; Segatto, Marcelo E. V.; Silva, Jair A. L.

    2017-05-01

    Block-level detection is required to decode what may be classified as selective control information (SCI) such as control format indicator in 4G-long-term evolution systems. Using optical orthogonal frequency division multiplexing over radio-over-fiber (RoF) links, we report the experimental evaluation of an SCI detection scheme based on a time-domain correlation (TDC) technique in comparison with the conventional maximum likelihood (ML) approach. When compared with the ML method, it is shown that the TDC method improves detection performance over both 20 and 40 km of standard single mode fiber (SSMF) links. We also report a performance analysis of the TDC scheme in noisy visible light communication channel models after propagation through 40 km of SSMF. Experimental and simulation results confirm that the TDC method is attractive for practical orthogonal frequency division multiplexing-based RoF and fiber-wireless systems. Unlike the ML method, another key benefit of the TDC is that it requires no channel estimation.

  20. Label-free detection of real-time DNA amplification using a nanofluidic diffraction grating

    NASA Astrophysics Data System (ADS)

    Yasui, Takao; Ogawa, Kensuke; Kaji, Noritada; Nilsson, Mats; Ajiri, Taiga; Tokeshi, Manabu; Horiike, Yasuhiro; Baba, Yoshinobu

    2016-08-01

    Quantitative DNA amplification using fluorescence labeling has played an important role in the recent, rapid progress of basic medical and molecular biological research. Here we report a label-free detection of real-time DNA amplification using a nanofluidic diffraction grating. Our detection system observed intensity changes during DNA amplification of diffracted light derived from the passage of a laser beam through nanochannels embedded in a microchannel. Numerical simulations revealed that the diffracted light intensity change in the nanofluidic diffraction grating was attributed to the change of refractive index. We showed the first case reported to date for label-free detection of real-time DNA amplification, such as specific DNA sequences from tubercle bacilli (TB) and human papillomavirus (HPV). Since our developed system allows quantification of the initial concentration of amplified DNA molecules ranging from 1 fM to 1 pM, we expect that it will offer a new strategy for developing fundamental techniques of medical applications.

  1. A novel CMOS image sensor system for quantitative loop-mediated isothermal amplification assays to detect food-borne pathogens.

    PubMed

    Wang, Tiantian; Kim, Sanghyo; An, Jeong Ho

    2017-02-01

    Loop-mediated isothermal amplification (LAMP) is considered as one of the alternatives to the conventional PCR and it is an inexpensive portable diagnostic system with minimal power consumption. The present work describes the application of LAMP in real-time photon detection and quantitative analysis of nucleic acids integrated with a disposable complementary-metal-oxide semiconductor (CMOS) image sensor. This novel system works as an amplification-coupled detection platform, relying on a CMOS image sensor, with the aid of a computerized circuitry controller for the temperature and light sources. The CMOS image sensor captures the light which is passing through the sensor surface and converts into digital units using an analog-to-digital converter (ADC). This new system monitors the real-time photon variation, caused by the color changes during amplification. Escherichia coli O157 was used as a proof-of-concept target for quantitative analysis, and compared with the results for Staphylococcus aureus and Salmonella enterica to confirm the efficiency of the system. The system detected various DNA concentrations of E. coli O157 in a short time (45min), with a detection limit of 10fg/μL. The low-cost, simple, and compact design, with low power consumption, represents a significant advance in the development of a portable, sensitive, user-friendly, real-time, and quantitative analytic tools for point-of-care diagnosis. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. Sensitive determination of sulfonamides in environmental water by capillary electrophoresis coupled with both silvering detection window and in-capillary optical fiber light-emitting diode-induced fluorescence detector.

    PubMed

    Ji, Hongyun; Wu, Yu; Duan, Zhijuan; Yang, Feng; Yuan, Hongyan; Xiao, Dan

    2017-02-01

    A new detector, silvering detection window and in-capillary optical fiber light-emitting diode-induced fluorescence detector (SDW-ICOF-LED-IFD), is introduced for capillary electrophoresis (CE). The strategy of the work was that half surface of the detection window was coated with silver mirror, which could reflect the undetected fluorescence to the photomultiplier tube to be detected, consequently enhancing the detection sensitivity. Sulfonamides (SAs) are important antibiotics that achieved great applications in many fields. However, they pose a serious threat on the environment and human health when they enter into the environment. The SDW-ICOF-LED-IFD-CE system was used to determine fluorescein isothiocyanate (FITC)-labeled sulfadoxine (SDM), sulfaguanidine (SGD) and sulfamonomethoxine sodium (SMM-Na) in environmental water. The detection results obtained by the SDW-ICOF-LED-IFD-CE system were compared to those acquired by the CE with in-capillary optical fiber light-emitting diode-induced fluorescence detection (ICOF-LED-IFD-CE). The limits of detection (LODs) of SDW-ICOF-LED-IFD-CE and ICOF-LED-IFD-CE were 1.0-2.0 nM and 2.5-7.7 nM (S/N = 3), respectively. The intraday (n = 6) and interday (n = 6) precision of migration time and corresponding peak area for both types of CE were all less than 0.86% and 3.68%, respectively. The accuracy of the proposed method was judged by employing standard addition method, and recoveries obtained were in the range of 92.5-102.9%. The results indicated that the sensitivity of the SDW-ICOF-LED-IFD-CE system was improved, and that its reproducibility and accuracy were satisfactory. It was successfully applied to analyze SAs in environmental water. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Evaluation of dental enamel caries assessment using Quantitative Light Induced Fluorescence and Optical Coherence Tomography.

    PubMed

    Maia, Ana Marly Araújo; de Freitas, Anderson Zanardi; de L Campello, Sergio; Gomes, Anderson Stevens Leônidas; Karlsson, Lena

    2016-06-01

    An in vitro study of morphological alterations between sound dental structure and artificially induced white spot lesions in human teeth, was performed through the loss of fluorescence by Quantitative Light-Induced Fluorescence (QLF) and the alterations of the light attenuation coefficient by Optical Coherence Tomography (OCT). To analyze the OCT images using a commercially available system, a special algorithm was applied, whereas the QLF images were analyzed using the software available in the commercial system employed. When analyzing the sound region against white spot lesions region by QLF, a reduction in the fluorescence intensity was observed, whilst an increase of light attenuation by the OCT system occurred. Comparison of the percentage of alteration between optical properties of sound and artificial enamel caries regions showed that OCT processed images through the attenuation of light enhanced the tooth optical alterations more than fluorescence detected by QLF System. QLF versus OCT imaging of enamel caries: a photonics assessment. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. SPED light sheet microscopy: fast mapping of biological system structure and function

    PubMed Central

    Tomer, Raju; Lovett-Barron, Matthew; Kauvar, Isaac; Andalman, Aaron; Burns, Vanessa M.; Sankaran, Sethuraman; Grosenick, Logan; Broxton, Michael; Yang, Samuel; Deisseroth, Karl

    2016-01-01

    The goal of understanding living nervous systems has driven interest in high-speed and large field-of-view volumetric imaging at cellular resolution. Light-sheet microscopy approaches have emerged for cellular-resolution functional brain imaging in small organisms such as larval zebrafish, but remain fundamentally limited in speed. Here we have developed SPED light sheet microscopy, which combines large volumetric field-of-view via an extended depth of field with the optical sectioning of light sheet microscopy, thereby eliminating the need to physically scan detection objectives for volumetric imaging. SPED enables scanning of thousands of volumes-per-second, limited only by camera acquisition rate, through the harnessing of optical mechanisms that normally result in unwanted spherical aberrations. We demonstrate capabilities of SPED microscopy by performing fast sub-cellular resolution imaging of CLARITY mouse brains and cellular-resolution volumetric Ca2+ imaging of entire zebrafish nervous systems. Together, SPED light sheet methods enable high-speed cellular-resolution volumetric mapping of biological system structure and function. PMID:26687363

  5. Detection system of capillary array electrophoresis microchip based on optical fiber

    NASA Astrophysics Data System (ADS)

    Yang, Xiaobo; Bai, Haiming; Yan, Weiping

    2009-11-01

    To meet the demands of the post-genomic era study and the large parallel detections of epidemic diseases and drug screening, the high throughput micro-fluidic detection system is needed urgently. A scanning laser induced fluorescence detection system based on optical fiber has been established by using a green laser diode double-pumped solid-state laser as excitation source. It includes laser induced fluorescence detection subsystem, capillary array electrophoresis micro-chip, channel identification unit and fluorescent signal processing subsystem. V-shaped detecting probe composed with two optical fibers for transmitting the excitation light and detecting induced fluorescence were constructed. Parallel four-channel signal analysis of capillary electrophoresis was performed on this system by using Rhodamine B as the sample. The distinction of different samples and separation of samples were achieved with the constructed detection system. The lowest detected concentration is 1×10-5 mol/L for Rhodamine B. The results show that the detection system possesses some advantages, such as compact structure, better stability and higher sensitivity, which are beneficial to the development of microminiaturization and integration of capillary array electrophoresis chip.

  6. Investigations of soft and hard tissues in oral cavity by spectral domain optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Madjarova, Violeta Dimitrova; Yasuno, Yoshiaki; Makita, Shuichi; Hori, Yasuaki; Voeffray, Jean-Baptiste; Itoh, Masahide; Yatagai, Toyohiko; Tamura, Masami; Nanbu, Toshiyuki

    2006-02-01

    Fourier Domain Optical Coherence Tomography (SD-OCT) systems for dental measurements are demonstrated. Two systems have been developed. The first system is fiber based Michelson interferometer with super luminescent diodes at 1310 nm and 100 nm FWHM as a light source. The sensitivity of the system was 106 dB with depth measurement range in air of 2.5 mm. The second systems is a fiber based Mach-Zehnder interferometer with wavelength scanning laser as light source at center wavelength of 1310 nm, wavelength range of 110 nm and scanning rate of 20 KHz. The sensitivity of the system is 112 dB and depth measurement range in air is 6 mm. Both systems can acquire real-time three dimensional (3-D) images in the range of several second. The systems were applied for early caries detection in tooth, for diagnostics of tooth condition after operational tooth treatment, and for diagnostics of the alveolar bone structure. In-vivo measurements were performed on two volunteers. The systems were able to detect discontinuities in tooth and resin filling after tooth treatment. In addition early carries lesion was detected in one of the volunteers. The 3-D profile of the alveolar bone was acquired for first time with non-contact method.

  7. Setting up a mobile Lidar (DIAL) system for detecting chemical warfare agents

    NASA Astrophysics Data System (ADS)

    Kavosh Tehrani, M.; Mohammad, M. Malek; Jaafari, E.; Mobashery, A.

    2015-03-01

    The mobile light detection and ranging DIAL system of Malek Ashtar University of Technology has been developed for the detection of chemical warfare agents whose absorption wavelengths are in the range of 9.2-10.8 μm tunable CO2 lasers of the system. In this paper, this system is first described and then ammonia detection is analyzed experimentally. Also, experimental results of detecting a sarin agent simulant, dimethyl-methyl phosphonate (DMMP), are presented. The power levels received from different ranges to detect specific concentrations of NH3 and DMMP have been measured and debated. The primary test results with a 150 ns clipped pulse width by passive pinhole plasma shutter indicate that the system is capable of monitoring several species of pollutants in the range of about 1 km, with a 20 m spatial and 2 min temporal resolution.

  8. A Support System for Mouse Operations Using Eye-Gaze Input

    NASA Astrophysics Data System (ADS)

    Abe, Kiyohiko; Nakayama, Yasuhiro; Ohi, Shoichi; Ohyama, Minoru

    We have developed an eye-gaze input system for people with severe physical disabilities, such as amyotrophic lateral sclerosis (ALS) patients. This system utilizes a personal computer and a home video camera to detect eye-gaze under natural light. The system detects both vertical and horizontal eye-gaze by simple image analysis, and does not require special image processing units or sensors. Our conventional eye-gaze input system can detect horizontal eye-gaze with a high degree of accuracy. However, it can only classify vertical eye-gaze into 3 directions (up, middle and down). In this paper, we propose a new method for vertical eye-gaze detection. This method utilizes the limbus tracking method for vertical eye-gaze detection. Therefore our new eye-gaze input system can detect the two-dimension coordinates of user's gazing point. By using this method, we develop a new support system for mouse operation. This system can move the mouse cursor to user's gazing point.

  9. Continuous operation of four-state continuous-variable quantum key distribution system

    NASA Astrophysics Data System (ADS)

    Matsubara, Takuto; Ono, Motoharu; Oguri, Yusuke; Ichikawa, Tsubasa; Hirano, Takuya; Kasai, Kenta; Matsumoto, Ryutaroh; Tsurumaru, Toyohiro

    2016-10-01

    We report on the development of continuous-variable quantum key distribution (CV-QKD) system that are based on discrete quadrature amplitude modulation (QAM) and homodyne detection of coherent states of light. We use a pulsed light source whose wavelength is 1550 nm and repetition rate is 10 MHz. The CV-QKD system can continuously generate secret key which is secure against entangling cloner attack. Key generation rate is 50 kbps when the quantum channel is a 10 km optical fiber. The CV-QKD system we have developed utilizes the four-state and post-selection protocol [T. Hirano, et al., Phys. Rev. A 68, 042331 (2003).]; Alice randomly sends one of four states {|+/-α⟩,|+/-𝑖α⟩}, and Bob randomly performs x- or p- measurement by homodyne detection. A commercially available balanced receiver is used to realize shot-noise-limited pulsed homodyne detection. GPU cards are used to accelerate the software-based post-processing. We use a non-binary LDPC code for error correction (reverse reconciliation) and the Toeplitz matrix multiplication for privacy amplification.

  10. Image overlay solution based on threshold detection for a compact near infrared fluorescence goggle system

    NASA Astrophysics Data System (ADS)

    Gao, Shengkui; Mondal, Suman B.; Zhu, Nan; Liang, RongGuang; Achilefu, Samuel; Gruev, Viktor

    2015-01-01

    Near infrared (NIR) fluorescence imaging has shown great potential for various clinical procedures, including intraoperative image guidance. However, existing NIR fluorescence imaging systems either have a large footprint or are handheld, which limits their usage in intraoperative applications. We present a compact NIR fluorescence imaging system (NFIS) with an image overlay solution based on threshold detection, which can be easily integrated with a goggle display system for intraoperative guidance. The proposed NFIS achieves compactness, light weight, hands-free operation, high-precision superimposition, and a real-time frame rate. In addition, the miniature and ultra-lightweight light-emitting diode tracking pod is easy to incorporate with NIR fluorescence imaging. Based on experimental evaluation, the proposed NFIS solution has a lower detection limit of 25 nM of indocyanine green at 27 fps and realizes a highly precise image overlay of NIR and visible images of mice in vivo. The overlay error is limited within a 2-mm scale at a 65-cm working distance, which is highly reliable for clinical study and surgical use.

  11. Arrays of Segmented, Tapered Light Guides for Use With Large, Planar Scintillation Detectors

    NASA Astrophysics Data System (ADS)

    Raylman, Raymond R.; Vaigneur, Keith; Stolin, Alexander V.; Jaliparthi, Gangadhar

    2015-06-01

    Metabolic imaging techniques can potentially improve detection and diagnosis of cancer in women with radiodense and/or fibrocystic breasts. Our group has previously developed a high-resolution positron emission tomography imaging and biopsy device (PEM-PET) to detect and guide the biopsy of suspicious breast lesions. Initial testing revealed that the imaging field-of-view (FOV) of the scanner was smaller than the physical size of the detector's active area, which could hinder sampling of breast areas close to the chest wall. The purpose of this work was to utilize segmented, tapered light guides for optically coupling the scintillator arrays to arrays of position-sensitive photomultipliers to increase both the active FOV and identification of individual scintillator elements. Testing of the new system revealed that the optics of these structures made it possible to discern detector elements from the complete active area of the detector face. In the previous system the top and bottom rows and left and right columns were not identifiable. Additionally, use of the new light guides increased the contrast of individual detector elements by up to 129%. Improved element identification led to a spatial resolution increase by approximately 12%. Due to attenuation of light in the light guides the detector energy resolution decreased from 18.5% to 19.1%. Overall, these improvements should increase the field-of-view and spatial resolution of the dedicated breast-PET system.

  12. Hyperbaric Chamber Equipment: A Consolidated Equipment List from Selected Multiplace Hyperbaric Facilities.

    DTIC Science & Technology

    1983-12-01

    carbon dioxide scrubbers , air conditioning, communications, lighting, and fire detecting and fire extinguishing systems. Medical support equipment was...10 14 Humidity...............................11 5. Hydrocarb on...........................11 B. Carbon Dioxide Scrubbers .....................11 C...and ancillary equipment included gas/vapor monitoring equipment, carbon dioxide scrubbers , air conditioning, communications, lighting, and fire

  13. PePSS - A portable sky scanner for measuring extremely low night-sky brightness

    NASA Astrophysics Data System (ADS)

    Kocifaj, Miroslav; Kómar, Ladislav; Kundracik, František

    2018-05-01

    A new portable sky scanner designed for low-light-level detection at night is developed and employed in night sky brightness measurements in a rural region. The fast readout, adjustable sensitivity and linear response guaranteed in 5-6 orders of magnitude makes the device well suited for narrow-band photometry in both dark areas and bright urban and suburban environments. Quasi-monochromatic night-sky brightness data are advantageous in the accurate characterization of spectral power distribution of scattered and emitted light and, also allows for the possibility to retrieve light output patterns from whole-city light sources. The sky scanner can operate in both night and day regimes, taking advantage of the complementarity of both radiance data types. Due to its inherent very high sensitivity the photomultiplier tube could be used in night sky radiometry, while the spectrometer-equipped system component capable of detecting elevated intensities is used in daylight monitoring. Daylight is a source of information on atmospheric optical properties that in turn are necessary in processing night sky radiances. We believe that the sky scanner has the potential to revolutionize night-sky monitoring systems.

  14. Plant Chlorophyll Content Imager with Reference Detection Signals

    NASA Technical Reports Server (NTRS)

    Spiering, Bruce A. (Inventor); Carter, Gregory A. (Inventor)

    2000-01-01

    A portable plant chlorophyll imaging system is described which collects light reflected from a target plant and separates the collected light into two different wavelength bands. These wavelength bands, or channels, are described as having center wavelengths of 700 nm and 840 nm. The light collected in these two channels is processed using synchronized video cameras. A controller provided in the system compares the level of light of video images reflected from a target plant with a reference level of light from a source illuminating the plant. The percent of reflection in the two separate wavelength bands from a target plant are compared to provide a ratio video image which indicates a relative level of plant chlorophyll content and physiological stress. Multiple display modes are described for viewing the video images.

  15. Fiber optical assembly for fluorescence spectrometry

    DOEpatents

    Carpenter, II, Robert W.; Rubenstein, Richard; Piltch, Martin; Gray, Perry

    2010-12-07

    A system for analyzing a sample for the presence of an analyte in a sample. The system includes a sample holder for containing the sample; an excitation source, such as a laser, and at least one linear array radially disposed about the sample holder. Radiation from the excitation source is directed to the sample, and the radiation induces fluorescent light in the sample. Each linear array includes a plurality of fused silica optical fibers that receive the fluorescent light and transmits a fluorescent light signal from the first end to an optical end port of the linear array. An end port assembly having a photo-detector is optically coupled to the optical end port. The photo-detector detects the fluorescent light signal and converts the fluorescent light signal into an electrical signal.

  16. Tracking Dynamic Changes and Monitoring Socioeconomic Parameters in Algeria Between 1993 and 2012, Using Nighttime Light Remote Sensing

    NASA Astrophysics Data System (ADS)

    Faouzi, B.; Washaya, P.

    2017-09-01

    This paper is based on using DMSP-OLS data from satellites nighttime light observations to detect both sources of light emissions in Algeria from human settlement areas and gas flaring from oil-extraction and natural gas production. We used the time series of data from DMSP-OLS images to examine the spatial and temporal characteristics of urban development in 48 Algerian provinces from 1993 to 2012. A systematic nighttime light calibration method was used to improve the consistency and comparability of the DSMPOSL images and then a separation is made between light detected from human settlements and light detected from gas flaring in order to allow us to study human settlements without other light emissions and then assess the suitability of using DMSP data in southern Algeria and its ability to monitor gas flaring. Linear regression methods were developed to identify the dynamic change of nighttime light and estimated its growth directions at pixel level. This work is the first to use nighttime light observations to detect and monitor the growth of human settlements in North Africa. In this study, we made use of DMSP-OLS data as a return ticket to the years of crises and we found the most affected provinces during that period. The DMSP-OLS data proved to be an index of growth in the economy during the period of stability in Algeria expressed by positive dynamic changes in the lighted area in all Algerian provinces. We used NTL data as an alternative to annual growth indexes for each province, which are unavailable, and its help as a monitoring system for socioeconomic parameters to fill the gap of data availability. We also proposed nighttime light remote sensing data as a useful tool to control and reduce CO2 emissions in Algeria's petroleum sector.

  17. Application of laser-induced autofluorescence spectra detection system in human colorectal cancer in-vivo screening

    NASA Astrophysics Data System (ADS)

    Chia, Teck Chee; Fu, Sheng; Chia, Yee Hong; Kwek, Leong Chuan; Tang, Choong Leong

    2005-09-01

    This study aimed at applying Laser induced-autofluorescence (LIAF) diagnostics method as an in-vivo screening of colorectal polyplcancer. The spectrum algorithm based on the ratio of autofluorescence intensity was used to identify the diseased tissues from the normal tissues as it was generally performed better than an algorithm based only simply on the intensity of the spectrum. Histopathological biopsy results were compared with the detected AF spectra characteristics for different kinds of polyps. 73 patients had been examined via the LIAF spectroscopy detection system during their colonoscopy screening in Endoscopy Center, Singapore General Hospital. The autofluorescence from the surface of the colorectal tissues under 405 nm laser light excitation was detected using our detecting system. In the experimental investigation two groups of patients were involved. One group was "abnormal" group. There were 25 patients belonging to this group since polyps or carcinoma was found in their colorectal tract during colonoscopy. The histopathology reports confirm the group classification. Total 36 polyps' AF spectra and 9 carcinoma' AF spectra were detected from 25 patients of the abnormal group during their regular endoscopy examination. The intensity ratios RI-680/I-500 and RI-630/I-500 of polyps/cancerous AF spectra and intensity ratios of corresponding normal colorectal AF spectra were calculated. Two critical intensity ratios for separating the AF intensity ratios RI-680/I-500 and RI-630/I-500 of normal and abnormal colorectal tissues were defined as 0.5 and 0.6 respectively. Using the critical intensity ratio values, 48 "normal" group patients' rectums were checked via the LIAF detection system. There were 20 patients (41.7%) whose AF spectra of colorectal tract mucosa belonging to abnormal spectra. However, these 20 patients had not been found under white light via traditional endoscopy. For small diseased area like small plat polyp disease and carcinoma, it was very difficult to identify under white light by endoscopy. However, the LIAF spectra technique and AF intensity ratio algorithm was able to detect these kinds of abnormal area earlier than traditional endoscopy. Using this algorithm, it is able to identify the onset of abnormal tissue growth during real-time clinical endoscope examination.

  18. High level expression and immunochemical characterization of botulinum neurotoxin type F light chain.

    PubMed

    Chauhan, Ritika; Chauhan, Vinita; Rao, Mula Kameshwar; Chaudhary, Dilip; Bhagyawant, Sameer; Dhaked, Ram Kumar

    2018-06-01

    Botulinum neurotoxins (BoNTs) are the most toxic biological substances known. Their potential use as biological warfare agent results in their classification as category A biowarfare agent by Centers for Disease Control and Prevention (CDC), USA. Presently, there are no approved detection system and pharmacological treatments for BoNT intoxication. Although a toxoid vaccine is available for immuno-prophylaxis, vaccines cannot reverse the effect of pre-translocated toxin. Direct handling of the live BoNTs for developing detection and therapeutics may pose fatal danger. This concern was addressed by purifying the recombinant catalytically active light chain of BoNT/F. BoNT/F-LC gene was amplified from the genomic DNA using specifically designed primers and expressed in Escherichia coli. Expression and purification profile were optimized under different conditions for biologically active light chain production. Specific polyclonal antibodies generated against type F illustrates in vivo neutralization in mice and rabbit. These antibodies play key role in conceiving the development of high throughput SPR based detection system which is a highly precise label free technique for protein interaction analysis. The presented work is first of its kind, signifying the production of highly stable and active rBoNT/F-LC and its immunochemical characterization. The study aids in paving the path towards developing a persistent detection system as well as in presenting comprehended scheme for in vitro small molecule therapeutics analysis. Copyright © 2018 Elsevier Inc. All rights reserved.

  19. The New Horizons and Hubble Space Telescope search for rings, dust, and debris in the Pluto-Charon system

    NASA Astrophysics Data System (ADS)

    Lauer, Tod R.; Throop, Henry B.; Showalter, Mark R.; Weaver, Harold A.; Stern, S. Alan; Spencer, John R.; Buie, Marc W.; Hamilton, Douglas P.; Porter, Simon B.; Verbiscer, Anne J.; Young, Leslie A.; Olkin, Cathy B.; Ennico, Kimberly; New Horizons Science Team

    2018-02-01

    We conducted an extensive search for dust or debris rings in the Pluto-Charon system before, during, and after the New Horizons encounter in July 2015. Methodologies included attempting to detect features by back-scattered light during the approach to Pluto (phase angle α ∼ 15°), in situ detection of impacting particles, a search for stellar occultations near the time of closest approach, and by forward-scattered light imaging during departure (α ∼ 165°). An extensive search using the Hubble Space Telescope (HST) prior to the encounter also contributed to the final ring limits. No rings, debris, or dust features were observed, but our new detection limits provide a substantially improved picture of the environment throughout the Pluto-Charon system. Searches for rings in back-scattered light covered the range 35,000-250,000 km from the system barycenter, a zone that starts interior to the orbit of Styx, the innermost minor satellite, and extends out to four times the orbital radius of Hydra, the outermost known satellite. We obtained our firmest limits using data from the New Horizons LORRI camera in the inner half of this region. Our limits on the normal I/F of an unseen ring depends on the radial scale of the rings: 2 ×10-8 (3σ) for 1500 km wide rings, 1 ×10-8 for 6000 km rings, and 7 ×10-9 for 12,000 km rings. Beyond ∼ 100, 000 km from Pluto, HST observations limit normal I/F to ∼ 8 ×10-8 . Searches for dust features from forward-scattered light extended from the surface of Pluto to the Pluto-Charon Hill sphere (rHill = 6.4 ×106 km). No evidence for rings or dust clouds was detected to normal I/F limits of ∼ 8.9 ×10-7 on ∼ 104 km scales. Four stellar occulation observations also probed the space interior to Hydra, but again no dust or debris was detected. The Student Dust Counter detected one particle impact 3.6 × 106 km from Pluto, but this is consistent with the interplanetary space environment established during the cruise of New Horizons. Elsewhere in the solar system, small moons commonly share their orbits with faint dust rings. Our results support recent dynamical studies suggesting that small grains are quickly lost from the Pluto-Charon system due to solar radiation pressure, whereas larger particles are orbitally unstable due to ongoing perturbations by the known moons.

  20. Optical imaging module for astigmatic detection system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Wei-Min; Cheng, Chung-Hsiang; Department of Mechanical Engineering, National Taiwan University, Taipei 10617, Taiwan

    2016-05-15

    In this paper, an optical imaging module design for an astigmatic detection system (ADS) is presented. The module is based on a commercial optical pickup unit (OPU) and it contains a coaxial illuminant for illuminating a specimen. Furthermore, the imaging module facilitates viewing the specimen and the detection laser spot of the ADS with a lateral resolution of approximately 1 μm without requiring the removal of an element of the OPU. Two polarizers and one infrared filter are used to eliminate stray laser light in the OPU and stray light produced by the illuminant. Imaging modules designed for digital versatilemore » disks (DVDs) and Blu-ray DVDs were demonstrated. Furthermore, the module can be used for imaging a small cantilever with approximate dimensions of 2 μm (width) × 5 μm (length), and therefore, it has the potential to be used in high-speed atomic force microscopy.« less

  1. Quantitative surface temperature measurement using two-color thermographic phosphors and video equipment

    NASA Technical Reports Server (NTRS)

    Buck, Gregory M. (Inventor)

    1989-01-01

    A thermal imaging system provides quantitative temperature information and is particularly useful in hypersonic wind tunnel applications. An object to be measured is prepared by coating with a two-color, ultraviolet-activated, thermographic phosphor. The colors emitted by the phosphor are detected by a conventional color video camera. A phosphor emitting blue and green light with a ratio that varies depending on temperature is used so that the intensity of light in the blue and green wavelengths detected by the blue and green tubes in the video camera can be compared. Signals representing the intensity of blue and green light at points on the surface of a model in a hypersonic wind tunnel are used to calculate a ratio of blue to green light intensity which provides quantitative temperature information for the surface of the model.

  2. Coupling a versatile aerosol apparatus to a synchrotron: Vacuum ultraviolet light scattering, photoelectron imaging, and fragment free mass spectrometry

    NASA Astrophysics Data System (ADS)

    Shu, Jinian; Wilson, Kevin R.; Ahmed, Musahid; Leone, Stephen R.

    2006-04-01

    An aerosol apparatus has been coupled to the Chemical Dynamics Beamline of the Advanced Light Source at Lawrence Berkeley National Laboratory. This apparatus has multiple capabilities for aerosol studies, including vacuum ultraviolet (VUV) light scattering, photoelectron imaging, and mass spectroscopy of aerosols. By utilizing an inlet system consisting of a 200μm orifice nozzle and aerodynamic lenses, aerosol particles of ˜50nm-˜1μm in diameter can be sampled directly from atmospheric pressure. The machine is versatile and can probe carbonaceous aerosols generated by a laboratory flame, nebulized solutions of biological molecules, hydrocarbon aerosol reaction products, and synthesized inorganic nanoparticles. The sensitivity of this apparatus is demonstrated by the detection of nanoparticles with VUV light scattering, photoelectron imaging, and charged particle detection. In addition to the detection of nanoparticles, the thermal vaporization of aerosols on a heater tip leads to the generation of intact gas phase molecules. This phenomenon coupled to threshold single photon ionization, accessible with tunable VUV light, allows for fragment-free mass spectrometry of complex molecules. The initial experiments with light scattering, photoelectron imaging, and aerosol mass spectrometry reported here serve as a demonstration of the design philosophy and multiple capabilities of the apparatus.

  3. Development of a PET/Cerenkov-light hybrid imaging system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yamamoto, Seiichi, E-mail: s-yama@met.nagoya-u.ac.jp; Hamamura, Fuka; Kato, Katsuhiko

    2014-09-15

    Purpose: Cerenkov-light imaging is a new molecular imaging technology that detects visible photons from high-speed electrons using a high sensitivity optical camera. However, the merit of Cerenkov-light imaging remains unclear. If a PET/Cerenkov-light hybrid imaging system were developed, the merit of Cerenkov-light imaging would be clarified by directly comparing these two imaging modalities. Methods: The authors developed and tested a PET/Cerenkov-light hybrid imaging system that consists of a dual-head PET system, a reflection mirror located above the subject, and a high sensitivity charge coupled device (CCD) camera. The authors installed these systems inside a black box for imaging the Cerenkov-light.more » The dual-head PET system employed a 1.2 × 1.2 × 10 mm{sup 3} GSO arranged in a 33 × 33 matrix that was optically coupled to a position sensitive photomultiplier tube to form a GSO block detector. The authors arranged two GSO block detectors 10 cm apart and positioned the subject between them. The Cerenkov-light above the subject is reflected by the mirror and changes its direction to the side of the PET system and is imaged by the high sensitivity CCD camera. Results: The dual-head PET system had a spatial resolution of ∼1.2 mm FWHM and sensitivity of ∼0.31% at the center of the FOV. The Cerenkov-light imaging system's spatial resolution was ∼275μm for a {sup 22}Na point source. Using the combined PET/Cerenkov-light hybrid imaging system, the authors successfully obtained fused images from simultaneously acquired images. The image distributions are sometimes different due to the light transmission and absorption in the body of the subject in the Cerenkov-light images. In simultaneous imaging of rat, the authors found that {sup 18}F-FDG accumulation was observed mainly in the Harderian gland on the PET image, while the distribution of Cerenkov-light was observed in the eyes. Conclusions: The authors conclude that their developed PET/Cerenkov-light hybrid imaging system is useful to evaluate the merits and the limitations of Cerenkov-light imaging in molecular imaging research.« less

  4. Digital image profilers for detecting faint sources which have bright companions, phase 2

    NASA Technical Reports Server (NTRS)

    Morris, Elena; Flint, Graham

    1991-01-01

    A breadboard image profiling system developed for the first phase of this project demonstrated the potential for detecting extremely faint optical sources in the presence of light companions. Experimental data derived from laboratory testing of the device supports the theory that image profilers of this type may approach the theoretical limit imposed by photon statistics. The objective of Phase 2 of this program is the development of a ground-based multichannel image profiling system capable of detecting faint stellar objects slightly displaced from brighter stars. We have finalized the multichannel image profiling system and attempted three field tests.

  5. Optical emission line monitor with background observation and cancellation

    DOEpatents

    Goff, D.R.; Notestein, J.E.

    1985-01-04

    A fiber optics based optical emission line monitoring system is provided in which selected spectral emission lines, such as the sodium D-line emission in coal combustion, may be detected in the presence of interferring background or blackbody radiation with emissions much greater in intensity than that of the emission line being detected. A bifurcated fiber optic light guide is adapted at the end of one branch to view the combustion light which is guided to a first bandpass filter, adapted to the common trunk end of the fiber. A portion of the light is reflected back through the common trunk portion of the fiber to a second bandpass filter adapted to the end of the other branch of the fiber. The first filter bandpass is centered at a wavelength corresponding to the emission line to be detected with a bandwidth of about three nanometers (nm). The second filter is centered at the same wavelength but having a width of about 10 nm. First and second light detectors are located to view the light passing through the first and second filters respectively. Thus, the second detector is blind to the light corresponding to the emission line of interest detected by the first detector and the difference between the two detector outputs is uniquely indicative of the intensity of only the combustion flame emission of interest. This instrument can reduce the effects of interfering blackbody radiation by greater than 20 dB.

  6. Optical emission line monitor with background observation and cancellation

    DOEpatents

    Goff, David R.; Notestein, John E.

    1986-01-01

    A fiber optics based optical emission line monitoring system is provided in which selected spectral emission lines, such as the sodium D-line emission in coal combustion, may be detected in the presence of interferring background or blackbody radiation with emissions much greater in intensity than that of the emission line being detected. A bifurcated fiber optic light guide is adapted at the end of one branch to view the combustion light which is guided to a first bandpass filter, adapted to the common trunk end of the fiber. A portion of the light is reflected back through the common trunk portion of the fiber to a second bandpass filter adapted to the end of the other branch of the fiber. The first filter bandpass is centered at a wavelength corresponding to the emission line to be detected with a bandwidth of about three nanometers (nm). The second filter is centered at the same wavelength but having a width of about 10 nm. First and second light detectors are located to view the light passing through the first and second filters respectively. Thus, the second detector is blind to the light corresponding to the emission line of interest detected by the first detector and the difference between the two detector outputs is uniquely indicative of the intensity of only the combustion flame emission of interest. This instrument can reduce the effects of interferring blackbody radiation by greater than 20 dB.

  7. 40 CFR 265.1052 - Standards: Pumps in light liquid service.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... week for indications of liquids dripping from the pump seal. (b)(1) If an instrument reading of 10,000... the pump seal, a leak is detected. (c)(1) When a leak is detected, it shall be repaired as soon as... after each leak is detected. (d) Each pump equipped with a dual mechanical seal system that includes a...

  8. Detecting technology of biophotons

    NASA Astrophysics Data System (ADS)

    Ma, Junfu; Zhu, Zhaohui; Zhu, Yanbin

    2002-03-01

    A key technique of detecting the ultra-weak photon emission from biological system (UPE) is to change the light signal of an extremely weak level into electric signal of a considerable level when the photo-electric detecting system were be applied. This paper analyzed the difficult for detecting the ultra-weak photon emission from biological system (UPE) mainly is in the absence of high sensitivity detector in UV-visible-infra spectra region. An experimental setup for testing UPE in different spectral region was designed. Using the experimental setup the test data of different several spectral regions from 300 nm to 1060 nm has were tested. The test result show the UPE of living biological system exists in wide spectra region from UV- visible to infrared.

  9. The Kinetics of Crystallization of Colloids and Proteins: A Light Scattering Study

    NASA Technical Reports Server (NTRS)

    McClymer, Jim

    2002-01-01

    Hard-sphere colloidal systems serve as model systems for aggregation, nucleation, crystallization and gelation as well as interesting systems in their own right.There is strong current interest in using colloidal systems to form photonic crystals. A major scientific thrust of NASA's microgravity research is the crystallization of proteins for structural determination. The crystallization of proteins is a complicated process that requires a great deal of trial and error experimentation. In spite of a great deal of work, "better" protein crystals cannot always be grown in microgravity and conditions for crystallization are not well understood. Crystallization of colloidal systems interacting as hard spheres and with an attractive potential induced by entropic forces have been studied in a series of static light scattering experiments. Additionally, aggregation of a protein as a function of pH has been studied using dynamic light scattering. For our experiments we used PMMA (polymethylacrylate) spherical particles interacting as hard spheres, with no attractive potential. These particles have a radius of 304 nanometers, a density of 1.22 gm/ml and an index of refraction of 1.52. A PMMA colloidal sample at a volume fraction of approximately 54% was index matched in a solution of cycloheptyl bromide (CHB) and cis-decalin. The sample is in a glass cylindrical vial that is placed in an ALV static and dynamic light scattering goniometer system. The vial is immersed in a toluene bath for index matching to minimize flair. Vigorous shaking melts any colloidal crystals initially present. The sample is illuminated with diverging laser light (632.8 nanometers) from a 4x microscope objective placed so that the beam is approximately 1 cm in diameter at the sample location. The sample is rotated about its long axis at approximately 3.5 revolutions per minute (highest speed) as the colloidal crystal system is non-ergodic. The scattered light is detected at various angles using the ALV light detection optics, which is fed into an APD detector module and linked to a computer. The scattering angle (between 12 and 160 degrees), scattering angle step size (0.1 degree minimum) and acquisition time (minimum 3 s) is set by the user.

  10. Coherent Doppler Wind Lidar Technology for Space Based Wind Measurements Including SPARCLE

    NASA Technical Reports Server (NTRS)

    Kavaya, Michael J.; Singh, Upendra N.

    1999-01-01

    It has been over 30 years since coherent lidar systems first measured wind velocity, and over 20 years since the "ultimate application" of measuring Earth's winds from space was conceived. Coherent or heterodyne optical detection involves the combination (or mixing) of the returned optical field with a local oscillator (LO) laser's optical field on the optical detector. This detection technique yields the benefits of dramatically improved signal-to-noise ratios; insensitivity to detector noise, background light and multiply scattered light; reduction of the returned signal's dynamic range; and preservation of the optical signal spectrum for electronic and computer processing. (Note that lidar systems are also referred to as optical radar, laser radar, and LADAR systems.) Many individuals, agencies, and countries have pursued the goal of space-based wind measurements through technology development, experiments, field campaigns and studies.

  11. Evaluation of light detector surface area for functional Near Infrared Spectroscopy.

    PubMed

    Wang, Lei; Ayaz, Hasan; Izzetoglu, Meltem; Onaral, Banu

    2017-10-01

    Functional Near Infrared Spectroscopy (fNIRS) is an emerging neuroimaging technique that utilizes near infrared light to detect cortical concentration changes of oxy-hemoglobin and deoxy-hemoglobin non-invasively. Using light sources and detectors over the scalp, multi-wavelength light intensities are recorded as time series and converted to concentration changes of hemoglobin via modified Beer-Lambert law. Here, we describe a potential source for systematic error in the calculation of hemoglobin changes and light intensity measurements. Previous system characterization and analysis studies looked into various fNIRS parameters such as type of light source, number and selection of wavelengths, distance between light source and detector. In this study, we have analyzed the contribution of light detector surface area to the overall outcome. Results from Monte Carlo based digital phantoms indicated that selection of detector area is a critical system parameter in minimizing the error in concentration calculations. The findings here can guide the design of future fNIRS sensors. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Study of UV imaging technology for noninvasive detection of latent fingerprints

    NASA Astrophysics Data System (ADS)

    Li, Hong-xia; Cao, Jing; Niu, Jie-qing; Huang, Yun-gang

    2013-09-01

    Using UV imaging technology, according to the special absorption 、reflection 、scattering and fluorescence characterization of the various residues in fingerprints (fatty acid ester, protein, and carboxylic acid salts etc) to the UV light, weaken or eliminate the background disturbance to increase the brightness contrast of fingerprints with the background, and design、setup the illumination optical system and UV imaging system, the noninvasive detection of latent fingerprints remaining on various object surface are studied. In the illumination optical system, using the 266nm UV Nd:YAG solid state laser as illumination light source, by calculating the best coupling conditions of the laser beam with UV liquid core fiber and analyzing the beam transforming characterizations, we designed and setup the optical system to realize the UV imaging uniform illumination. In the UV imaging system, the UV lens is selected as the fingerprint imaging element, and the UV intensified CCD (ICCD) which consists of a second-generation UV image intensifier and a CCD coupled by fiber plate and taper directly are used as the imaging sensing element. The best imaging conditions of the UV lens with ICCD were analyzed and the imaging system was designed and setup. In this study, by analyzing the factors which influence the detection effect, optimal design and setup the illumination system and imaging system, latent fingerprints on the surface of the paint tin box、plastic、smooth paper、notebook paper and print paper were noninvasive detected and appeared, and the result meet the fingerprint identification requirements in forensic science.

  13. Determination of doxorubicin in plasma by using CE coupled with in-column tapered optic-fiber light-emitting diode induced fluorescence detection.

    PubMed

    Yang, Xiupei; Qian, Fan; Xie, Linxiang; Yang, Xiaocui; Cheng, Xiumei; Choi, Martin M F

    2014-03-01

    This paper proposes a novel strategy to enhance detection of doxorubicin in human plasma, using homemade CE combined with normal stacking mode (NSM). The detection system of CE named as in-column tapered optic-fiber light-emitting diode induced fluorescence detection system is economic and more sensitive that has been demonstrated in our previous work. The influence of sample matrix, BGE, applied voltage, and injection time on the efficiency of NSM were systematically investigated. The clean extracts were subjected to CE separation with optimal experimental conditions: Ethanol-water (1:1, v/v) was used as sample matrix, pH 4.12 15 mM sodium phosphate buffer solution containing 70% v/v ACN, applied voltage 23 kV and 45 s hydrodynamic injection at a height of 20 cm. The detection system displayed linear dynamic range from 6.4 to 1.13 × 10(3) ng/mL with a correlation coefficient of 0.9990 and LOD 2.2 ng/mL for doxorubicin (DOX). The proposed CE method has been successfully applied to determine DOX in human plasma which the recoveries of standard DOX added to human plasma were found to been the range of 93.8-104.6%. The results obtained demonstrate that our detection system combined with NSM is a good idea to enhance sensitivity in CE for routine determination of DOX in some biological specimens. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Intensity compensation for on-line detection of defects on fruit

    NASA Astrophysics Data System (ADS)

    Wen, Zhiqing; Tao, Yang

    1997-10-01

    A machine-vision sorting system was developed that utilizes the difference in light reflectance of fruit surfaces to distinguish the defective and good apples. To accommodate to the spherical reflectance characteristics of fruit with curved surface like apple, a spherical transform algorithm was developed that converts the original image to a non-radiant image without losing defective segments on the fruit. To prevent high-quality dark-colored fruit form being classified into the defective class and increase the defect detection rate for light-colored fruit, an intensity compensation method using maximum propagation was used. Experimental results demonstrated the effectiveness of the method based on maximum propagation and spherical transform for on-line detection of defects on apples.

  15. Demonstration of DFTS-OFDM and equalization technology using in VLC communication on the headset port of Android device

    NASA Astrophysics Data System (ADS)

    Wang, Fumin; Shi, Meng; Chi, Nan

    2016-10-01

    Visible light communication (VLC) is one of the hottest research directions in wireless communication. It is safe, fast and free of electromagnetic interference. We carry out the visible light communication using DFTS-OFDM modulation mode through the headset port to and take equalization technique to compensate the channel. In this paper, we first test the feasibility of the DFTS-OFDM modulated VLC system by analyzing the constellation and the transmission error rate via the headset interface of the smartphone. Then we change the peak value of the signal generated by the AWG as well as the static current to find the best working point. We tested the effect of changing the up-sample number on the BER performance of the communication system, and compared the BER performance of 16QAM and 8QAM modulation in different equalization method. We also do experiment to find how distance affect the performance of the communication and the maximum communication rate that can be achieved. We successfully demonstrated a visible light communication system detected by a headset port of a smart phone for a 32QAM DFTS-OFDM modulated signal of 27.5kb/s over a 3-meter free space transmission. The light source is traditional phosphorescent white LED. This result, as far as we know, is the highest data rate of VLC system via headset port detection.

  16. Automated macromolecular crystal detection system and method

    DOEpatents

    Christian, Allen T [Tracy, CA; Segelke, Brent [San Ramon, CA; Rupp, Bernard [Livermore, CA; Toppani, Dominique [Fontainebleau, FR

    2007-06-05

    An automated macromolecular method and system for detecting crystals in two-dimensional images, such as light microscopy images obtained from an array of crystallization screens. Edges are detected from the images by identifying local maxima of a phase congruency-based function associated with each image. The detected edges are segmented into discrete line segments, which are subsequently geometrically evaluated with respect to each other to identify any crystal-like qualities such as, for example, parallel lines, facing each other, similarity in length, and relative proximity. And from the evaluation a determination is made as to whether crystals are present in each image.

  17. Process Analyzer

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The ChemScan UV-6100 is a spectrometry system originally developed by Biotronics Technologies, Inc. under a Small Business Innovation Research (SBIR) contract. It is marketed to the water and wastewater treatment industries, replacing "grab sampling" with on-line data collection. It analyzes the light absorbance characteristics of a water sample, simultaneously detects hundreds of individual wavelengths absorbed by chemical substances in a process solution, and quantifies the information. Spectral data is then processed by ChemScan analyzer and compared with calibration files in the system's memory in order to calculate concentrations of chemical substances that cause UV light absorbance in specific patterns. Monitored substances can be analyzed for quality and quantity. Applications include detection of a variety of substances, and the information provided enables an operator to control a process more efficiently.

  18. Uniform Laser Excitation And Detection In Capillary Array Electrophoresis System And Method.

    DOEpatents

    Li, Qingbo; Zhou, Songsan; Liu, Changsheng

    2003-10-07

    A capillary electrophoresis system comprises capillaries positioned in parallel to each other forming a plane. The capillaries are configured to allow samples to migrate. A light source is configured to illuminate the capillaries and the samples therein. This causes the samples to emit light. A lens is configured to receive the light emitted by the samples and positioned directly over a first group of the capillaries and obliquely over a second group of the capillaries. The light source is further configured to illuminate the second group of capillaries more than the first group of the capillaries such that amount of light received by the lens from the first group of capillaries is substantially identical to amount of light received from the second group of capillaries when an identical amount of the samples is migrating through the first and second group capillaries.

  19. Method and system for sensing and identifying foreign particles in a gaseous environment

    NASA Technical Reports Server (NTRS)

    Choi, Sang H. (Inventor); Park, Yeonjoon (Inventor)

    2008-01-01

    An optical method and system sense and identify a foreign particle in a gaseous environment. A light source generates light. An electrically-conductive sheet has an array of holes formed through the sheet. Each hole has a diameter that is less than one quarter of the light's wavelength. The sheet is positioned relative to the light source such that the light is incident on one face of the sheet. An optical detector is positioned adjacent the sheet's opposing face and is spaced apart therefrom such that a gaseous environment is adapted to be disposed there between. Alterations in the light pattern detected by the optical detector indicate the presence of a foreign particle in the holes or on the sheet, while a laser induced fluorescence (LIF) signature associated with the foreign particle indicates the identity of the foreign particle.

  20. Development of blood vessel searching system for HMS

    NASA Astrophysics Data System (ADS)

    Kandani, Hirofumi; Uenoya, Toshiyuki; Uetsuji, Yasutomo; Nakamachi, Eiji

    2008-08-01

    In this study, we develop a new 3D miniature blood vessel searching system by using near-infrared LED light, a CMOS camera module with an image processing unit for a health monitoring system (HMS), a drug delivery system (DDS) which requires very high performance for automatic micro blood volume extraction and automatic blood examination. Our objective is to fabricate a highly reliable micro detection system by utilizing image capturing, image processing, and micro blood extraction devices. For the searching system to determine 3D blood vessel location, we employ the stereo method. The stereo method is a common photogrammetric method. It employs the optical path principle to detect 3D location of the disparity between two cameras. The principle for blood vessel visualization is derived from the ratio of hemoglobin's absorption of the near-infrared LED light. To get a high quality blood vessel image, we adopted an LED, with peak a wavelength of 940nm. The LED is set on the dorsal side of the finger and it irradiates the human finger. A blood vessel image is captured by a CMOS camera module, which is set below the palmer side of the finger. 2D blood vessel location can be detected by the luminance distribution of a one pixel line. To examine the accuracy of our detecting system, we carried out experiments using finger phantoms with blood vessel diameters of 0.5, 0.75, 1.0mm, at the depths of 0.5 ~ 2.0 mm from the phantom's surface. The experimental results of the estimated depth obtained by our detecting system shows good agreements with the given depths, and the viability of this system is confirmed.

  1. Integrated High Resolution Digital Color Light Sensor in 130 nm CMOS Technology

    PubMed Central

    Strle, Drago; Nahtigal, Uroš; Batistell, Graciele; Zhang, Vincent Chi; Ofner, Erwin; Fant, Andrea; Sturm, Johannes

    2015-01-01

    This article presents a color light detection system integrated in 130 nm CMOS technology. The sensors and corresponding electronics detect light in a CIE XYZ color luminosity space using on-chip integrated sensors without any additional process steps, high-resolution analog-to-digital converter, and dedicated DSP algorithm. The sensor consists of a set of laterally arranged integrated photodiodes that are partly covered by metal, where color separation between the photodiodes is achieved by lateral carrier diffusion together with wavelength-dependent absorption. A high resolution, hybrid, ∑∆ ADC converts each photo diode’s current into a 22-bit digital result, canceling the dark current of the photo diodes. The digital results are further processed by the DSP, which calculates normalized XYZ or RGB color and intensity parameters using linear transformations of the three photo diode responses by multiplication of the data with a transformation matrix, where the coefficients are extracted by training in combination with a pseudo-inverse operation and the least-mean square approximation. The sensor system detects the color light parameters with 22-bit accuracy, consumes less than 60 μA on average at 10 readings per second, and occupies approx. 0.8 mm2 of silicon area (including three photodiodes and the analog part of the ADC). The DSP is currently implemented on FPGA. PMID:26205275

  2. Results from the Rothney Astrophysical Observatory Variable Star Search Program: Background, Procedure, and Results from RAO Field 1

    NASA Astrophysics Data System (ADS)

    Williams, Michael D.; Milone, E. F.

    2013-12-01

    We describe a variable star search program and present the fully reduced results of a search in a 19 square degree (4.4 × 4.4) field centered on J2000 RA = 22:03:24, DEC= +18:54:32. The search was carried out with the Baker-Nunn Patrol Camera located at the Rothney Astrophysical Observatory in the foothills of the Canadian Rockies. A total of 26,271 stars were detected in the field, over a range of about 11-15 (instrumental) magnitudes. Our image processing made use of the IRAF version of the DAOPHOT aperture photometry routine and we used the ANOVA method to search for periodic variations in the light curves. We formally detected periodic variability in 35 stars, that we tentatively classify according to light curve characteristics: 6 EA (Algol), 5 EB (?? Lyrae), 19 EW (W UMa), and 5 RR (RR Lyrae) stars. Eleven of the detected variable stars have been reported previously in the literature. The eclipsing binary light curves have been analyzed with a package of light curve modeling programs and 25 have yielded converged solutions. Ten of these are of systems that are detached, 3 semi-detached, 10 overcontact, and 2 are of systems that appear to be in marginal contact. We discuss these results as well as the advantages and disadvantages of the instrument and of the program.

  3. Chip-to-chip optical link by using optical wiring method

    NASA Astrophysics Data System (ADS)

    Cho, In-Kui; Ahn, Seoung Ho; Jeong, Myung-Yung; Rho, Byung Sup; Park, Hyo Hoon

    2008-01-01

    A practical optical link system was prepared with a transmitter (Tx) and receiver (Rx). The optical TRx module consisted of a metal optical bench, a module printed circuit board (PCB), a driver/receiver IC, a VCSEL/PD array, and an optical link block composed of plastic optical fiber (POF). For the optical interconnection between the light-sources and detectors, an optical wiring method has been proposed to enable easy assembly. This paper provides a method for optical interconnection between an optical Tx and an optical Rx, comprising the following steps: (a) forming a light source device, an optical detection device, and an optical transmission unit on a substrate (metal optical bench (MOB)); (b) preparing a flexible optical transmission-connection medium (optical wiring link) to optically connect the light source device formed on the substrate with the optical detection device; and (c) directly connecting one end of the surface-finished optical transmission connection medium with the light source device and the other end with the optical detection device. A chip-to-chip optical link system constructed with TRx modules was fabricated and the optical characteristics were measured. The results clearly demonstrate that the use of an optical wiring method can provide robust and cost-effective assembly for vertical-cavity surface-emitting lasers (VCSELs) and photodiodes (PDs). We successfully achieved a 5 Gb/s data transmission rate with this optical link.

  4. A visible light imaging device for cardiac rate detection with reduced effect of body movement

    NASA Astrophysics Data System (ADS)

    Jiang, Xiaotian; Liu, Ming; Zhao, Yuejin

    2014-09-01

    A visible light imaging system to detect human cardiac rate is proposed in this paper. A color camera and several LEDs, acting as lighting source, were used to avoid the interference of ambient light. From people's forehead, the cardiac rate could be acquired based on photoplethysmography (PPG) theory. The template matching method was used after the capture of video. The video signal was discomposed into three signal channels (RGB) and the region of interest was chosen to take the average gray value. The green channel signal could provide an excellent waveform of pulse wave on the account of green lights' absorptive characteristics of blood. Through the fast Fourier transform, the cardiac rate was exactly achieved. But the research goal was not just to achieve the cardiac rate accurately. With the template matching method, the effects of body movement are reduced to a large extent, therefore the pulse wave can be detected even while people are in the moving state and the waveform is largely optimized. Several experiments are conducted on volunteers, and the results are compared with the ones gained by a finger clamped pulse oximeter. The contrast results between these two ways are exactly agreeable. This method to detect the cardiac rate and the pulse wave largely reduces the effects of body movement and can probably be widely used in the future.

  5. [Research on the temperature field detection method of hot forging based on long-wavelength infrared spectrum].

    PubMed

    Zhang, Yu-Cun; Wei, Bin; Fu, Xian-Bin

    2014-02-01

    A temperature field detection method based on long-wavelength infrared spectrum for hot forging is proposed in the present paper. This method combines primary spectrum pyrometry and three-stage FP-cavity LCTF. By optimizing the solutions of three group nonlinear equations in the mathematical model of temperature detection, the errors are reduced, thus measuring results will be more objective and accurate. Then the system of three-stage FP-cavity LCTF was designed on the principle of crystal birefringence. The system realized rapid selection of any wavelength in a certain wavelength range. It makes the response of the temperature measuring system rapid and accurate. As a result, without the emissivity of hot forging, the method can acquire exact information of temperature field and effectively suppress the background light radiation around the hot forging and ambient light that impact the temperature detection accuracy. Finally, the results of MATLAB showed that the infrared spectroscopy through the three-stage FP-cavity LCTF could meet the requirements of design. And experiments verified the feasibility of temperature measuring method. Compared with traditional single-band thermal infrared imager, the accuracy of measuring result was improved.

  6. Optical Sensing to Determine Tomato Plant Spacing for Precise Agrochemical Application: Two Scenarios

    PubMed Central

    Martínez-Guanter, Jorge; Garrido-Izard, Miguel; Valero, Constantino; Slaughter, David C.; Pérez-Ruiz, Manuel

    2017-01-01

    The feasibility of automated individual crop plant care in vegetable crop fields has increased, resulting in improved efficiency and economic benefits. A systems-based approach is a key feature in the engineering design of mechanization that incorporates precision sensing techniques. The objective of this study was to design new sensing capabilities to measure crop plant spacing under different test conditions (California, USA and Andalucía, Spain). For this study, three different types of optical sensors were used: an optical light-beam sensor (880 nm), a Light Detection and Ranging (LiDAR) sensor (905 nm), and an RGB camera. Field trials were conducted on newly transplanted tomato plants, using an encoder as a local reference system. Test results achieved a 98% accuracy in detection using light-beam sensors while a 96% accuracy on plant detections was achieved in the best of replications using LiDAR. These results can contribute to the decision-making regarding the use of these sensors by machinery manufacturers. This could lead to an advance in the physical or chemical weed control on row crops, allowing significant reductions or even elimination of hand-weeding tasks. PMID:28492504

  7. Optically-tracked handheld fluorescence imaging platform for monitoring skin response in the management of soft tissue sarcoma

    NASA Astrophysics Data System (ADS)

    Chamma, Emilie; Qiu, Jimmy; Lindvere-Teene, Liis; Blackmore, Kristina M.; Majeed, Safa; Weersink, Robert; Dickie, Colleen I.; Griffin, Anthony M.; Wunder, Jay S.; Ferguson, Peter C.; DaCosta, Ralph S.

    2015-07-01

    Standard clinical management of extremity soft tissue sarcomas includes surgery with radiation therapy. Wound complications (WCs) arising from treatment may occur due to bacterial infection and tissue breakdown. The ability to detect changes in these parameters during treatment may lead to earlier interventions that mitigate WCs. We describe the use of a new system composed of an autofluorescence imaging device and an optical three-dimensional tracking system to detect and coregister the presence of bacteria with radiation doses. The imaging device visualized erythema using white light and detected bacterial autofluorescence using 405-nm excitation light. Its position was tracked relative to the patient using IR reflective spheres and registration to the computed tomography coordinates. Image coregistration software was developed to spatially overlay radiation treatment plans and dose distributions on the white light and autofluorescence images of the surgical site. We describe the technology, its use in the operating room, and standard operating procedures, as well as demonstrate technical feasibility and safety intraoperatively. This new clinical tool may help identify patients at greater risk of developing WCs and investigate correlations between radiation dose, skin response, and changes in bacterial load as biomarkers associated with WCs.

  8. Ultra-sensitive chemical and biological analysis via specialty fibers with built-in microstructured optofluidic channels.

    PubMed

    Zhang, Nan; Li, Kaiwei; Cui, Ying; Wu, Zhifang; Shum, Perry Ping; Auguste, Jean-Louis; Dinh, Xuan Quyen; Humbert, Georges; Wei, Lei

    2018-02-13

    All-in-fiber optofluidics is an analytical tool that provides enhanced sensing performance with simplified analyzing system design. Currently, its advance is limited either by complicated liquid manipulation and light injection configuration or by low sensitivity resulting from inadequate light-matter interaction. In this work, we design and fabricate a side-channel photonic crystal fiber (SC-PCF) and exploit its versatile sensing capabilities in in-line optofluidic configurations. The built-in microfluidic channel of the SC-PCF enables strong light-matter interaction and easy lateral access of liquid samples in these analytical systems. In addition, the sensing performance of the SC-PCF is demonstrated with methylene blue for absorptive molecular detection and with human cardiac troponin T protein by utilizing a Sagnac interferometry configuration for ultra-sensitive and specific biomolecular specimen detection. Owing to the features of great flexibility and compactness, high-sensitivity to the analyte variation, and efficient liquid manipulation/replacement, the demonstrated SC-PCF offers a generic solution to be adapted to various fiber-waveguide sensors to detect a wide range of analytes in real time, especially for applications from environmental monitoring to biological diagnosis.

  9. On-off keying transmitter design for navigation by visible light communication

    NASA Astrophysics Data System (ADS)

    Louro, P.; Vieira, M.; Costa, J.; Vieira, M. A.

    2018-02-01

    White LEDS revolutionized the field of illumination technology mainly due to the energy saving effects. Besides lighting purposes LEDs can also be used in wireless communication systems when integrated in Visible Light Communication (VLC) systems. Indoor positioning for navigation in large buildings is currently under research to overcome the difficulties associated with the use of GPS in such environments. The motivation for this application is also supported by the possibility of taking advantage of an existing lighting and WiFi infrastructure. In this work it is proposed an indoor navigation system based on the use of VLC technology. The proposed system includes trichromatic white LEDs with the red and blue chips modulated at different frequencies and a pinpin photodetector with selective spectral sensitivity. Optoelectronic features of both optical sources and photodetector device are analyzed. The photodetector device consists two pin structures based on a-SiC:H and a-Si:H with geometrical configuration optimized for the detection of short and large wavelengths in the visible range. Its sensitivity is externally tuned by steady state optical bias. The localization algorithm makes use of the Fourier transform to identify the frequencies present in the photocurrent signal and the wavelength filtering properties of the sensor under front and back optical bias to detect the existing red and blue signals. The viability of the system was demonstrated through the implementation of an automatic algorithm to infer the photodetector cardinal direction. A capacitive optoelectronic model supports the experimental results and explains the device operation.

  10. 40 CFR 65.107 - Standards: Pumps in light liquid service.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... frequency of drips and to the sensor that indicates failure of the seal system, the barrier fluid system, or... or fuel gas system or connected by a closed vent system to a control device that complies with the... equipped with a sensor that will detect failure of the seal system, the barrier fluid system, or both. (v...

  11. Enhanced Automated Guidance System for Horizontal Auger Boring Based on Image Processing.

    PubMed

    Wu, Lingling; Wen, Guojun; Wang, Yudan; Huang, Lei; Zhou, Jiang

    2018-02-15

    Horizontal auger boring (HAB) is a widely used trenchless technology for the high-accuracy installation of gravity or pressure pipelines on line and grade. Differing from other pipeline installations, HAB requires a more precise and automated guidance system for use in a practical project. This paper proposes an economic and enhanced automated optical guidance system, based on optimization research of light-emitting diode (LED) light target and five automated image processing bore-path deviation algorithms. An LED light target was optimized for many qualities, including light color, filter plate color, luminous intensity, and LED layout. The image preprocessing algorithm, direction location algorithm, angle measurement algorithm, deflection detection algorithm, and auto-focus algorithm, compiled in MATLAB, are used to automate image processing for deflection computing and judging. After multiple indoor experiments, this guidance system is applied in a project of hot water pipeline installation, with accuracy controlled within 2 mm in 48-m distance, providing accurate line and grade controls and verifying the feasibility and reliability of the guidance system.

  12. Standoff detection of explosive molecules using nanosecond gated Raman spectroscopy

    NASA Astrophysics Data System (ADS)

    Chung, Jin Hyuk; Cho, Soo Gyeong

    2013-06-01

    Recently, improvised explosive device (IED) has been a serious threat for many countries. One of the approaches to alleviate this threat is standoff detection of explosive molecules used in IEDs. Raman spectroscopy is a prospective method among many technologies under research to achieve this goal. It provides unique information of the target materials, through which the ingredients used in IEDs can be analyzed and identified. The main problem of standoff Raman spectroscopic detection is the large background noise hindering weak Raman signals from the target samples. Typical background noise comes from both ambient fluorescent lights indoor and sunlight outdoor whose intensities are usually much larger than that of Raman scattering from the sample. Under the proper condition using pulse laser and ICCD camera with nanosecond pulse width and gating technology, we succeed to separate and remove these background noises from Raman signals. For this experiment, we build an optical system for standoff detection of explosive molecules. We use 532 nm, 10 Hz, Q-switching Nd:YAG laser as light source, and ICCD camera triggered by laser Qswitching time with proper gate delay regarding the flight time of Raman from target materials. Our detection system is successfully applied to detect and identify more than 20 ingredients of IEDs including TNT, RDX, and HMX which are located 10 to 54 meters away from the system.

  13. Reduction of Zika virus infectivity in platelet concentrates after treatment with ultraviolet C light and in plasma after treatment with methylene blue and visible light.

    PubMed

    Fryk, Jesse J; Marks, Denese C; Hobson-Peters, Jody; Watterson, Daniel; Hall, Roy A; Young, Paul R; Reichenberg, Stefan; Tolksdorf, Frank; Sumian, Chryslain; Gravemann, Ute; Seltsam, Axel; Faddy, Helen M

    2017-11-01

    Zika virus (ZIKV) has emerged as a potential threat to transfusion safety worldwide. Pathogen inactivation is one approach to manage this risk. In this study, the efficacy of the THERAFLEX UV-Platelets system and THERAFLEX MB-Plasma system to inactivate ZIKV in platelet concentrates (PCs) and plasma was investigated. PCs spiked with ZIKV were treated with the THERAFLEX UV-Platelets system at 0.05, 0.10, 0.15, and 0.20 J/cm 2 UVC. Plasma spiked with ZIKV was treated with the THERAFLEX MB-Plasma system at 20, 40, 60, and 120 J/cm 2 light at 630 nm with at least 0.8 µmol/L methylene blue (MB). Samples were taken before the first and after each illumination dose and tested for residual virus. For each system the level of viral reduction was determined. Treatment of PCs with THERAFLEX UV-Platelets system resulted in a mean of 5 log reduction in ZIKV infectivity at the standard UVC dose (0.20 J/cm 2 ), with dose dependency observed with increasing UVC dose. For plasma treated with MB and visible light, ZIKV infectivity was reduced by a mean of at least 5.68 log, with residual viral infectivity reaching the detection limit of the assay at 40 J/cm 2 (one-third the standard dose). Our study demonstrates that the THERAFLEX UV-Platelets system and THERAFLEX MB-Plasma system can reduce ZIKV infectivity in PCs and pooled plasma to the detection limit of the assays used. These findings suggest both systems have the capacity to be an effective option to manage potential ZIKV transfusion transmission risk. © 2017 AABB.

  14. Integrating Unmanned Aircraft Systems into Modern Policing in An Urban Environment

    DTIC Science & Technology

    2012-09-01

    University of Phoenix , 1994 Submitted in partial fulfillment of the requirements for the degree of MASTER OF ARTS IN SECURITY STUDIES (HOMELAND...PERSPECTIVE.................................................. 23 C. “ LIGHT ” UAS OPERATIONAL EXEMPTIONS ................................. 27 D...activity) utilizing a FLIR device capable of thermal imaging detection to determine if Kyllo was using powerful light to cultivate marijuana.37 The

  15. Optical fiber strain sensor for application in intelligent intruder detection systems

    NASA Astrophysics Data System (ADS)

    Stańczyk, Tomasz; Tenderenda, Tadeusz; Szostkiewicz, Lukasz; Bienkowska, Beata; Kunicki, Daniel; Murawski, Michal; Mergo, Pawel; Nasilowski, Tomasz

    2017-10-01

    Nowadays technology allows to create highly effective Intruder Detection Systems (IDS), that are able to detect the presence of an intruder within a defined area. In such systems the best performance can be achieved by combining different detection techniques in one system. One group of devices that can be applied in an IDS, are devices based on Fiber Optic Sensors (FOS). The FOS benefits from numerous advantages of optical fibers like: small size, light weight or high sensitivity. In this work we present a novel Microstructured Optical Fiber (MOF) characterized by increased strain sensitivity dedicated to distributed acoustic sensing for intelligent intruder detection systems. By designing the MOF with large air holes in close proximity to a fiber core, we increased the effective refractive index sensitivity to longitudinal strain. The presented fiber can be easily integrated in a floor system in order to detect any movement in the investigated area. We believe that sensors, based on the presented MOF, due to its numerous advantages, can find application in intelligent IDS.

  16. Tunable-optical-filter-based white-light interferometry for sensing.

    PubMed

    Yu, Bing; Wang, Anbo; Pickrell, Gary; Xu, Juncheng

    2005-06-15

    We describe tunable-optical-filter-based white-light interferometry for sensor interrogation. By introducing a tunable optical filter into a white-light interferometry system, one can interrogate an interferometer with either quadrature demodulation or spectral-domain detection at low cost. To demonstrate the feasibility of effectively demodulating various types of interferometric sensor, experiments have been performed using an extrinsic Fabry-Perot tunable filter to interrogate two extrinsic Fabry-Perot interferometric temperature sensors and a diaphragm-based pressure sensor.

  17. Design of indoor temperature and humidity detection system based on single chip microcomputer

    NASA Astrophysics Data System (ADS)

    Fu, Xiuwei; Fu, Li; Ma, Tianhui

    2018-03-01

    The indoor temperature and humidity detection system based on STC15F2K60S2 is designed in this paper. The temperature and humidity sensor DHT22 to monitor the indoor temperature and humidity are used, and the temperature and humidity data to the user's handheld device are wirelessly transmitted, when the temperature reaches or exceeds the user set the temperature alarm value, and the system sound and light alarm, to remind the user.

  18. Automatic Lamp and Fan Control Based on Microcontroller

    NASA Astrophysics Data System (ADS)

    Widyaningrum, V. T.; Pramudita, Y. D.

    2018-01-01

    In general, automation can be described as a process following pre-determined sequential steps with a little or without any human exertion. Automation is provided with the use of various sensors suitable to observe the production processes, actuators and different techniques and devices. In this research, the automation system developed is an automatic lamp and an automatic fan on the smart home. Both of these systems will be processed using an Arduino Mega 2560 microcontroller. A microcontroller is used to obtain values of physical conditions through sensors connected to it. In the automatic lamp system required sensors to detect the light of the LDR (Light Dependent Resistor) sensor. While the automatic fan system required sensors to detect the temperature of the DHT11 sensor. In tests that have been done lamps and fans can work properly. The lamp can turn on automatically when the light begins to darken, and the lamp can also turn off automatically when the light begins to bright again. In addition, it can concluded also that the readings of LDR sensors are placed outside the room is different from the readings of LDR sensors placed in the room. This is because the light intensity received by the existing LDR sensor in the room is blocked by the wall of the house or by other objects. Then for the fan, it can also turn on automatically when the temperature is greater than 25°C, and the fan speed can also be adjusted. The fan may also turn off automatically when the temperature is less than equal to 25°C.

  19. Design of measuring system for wire diameter based on sub-pixel edge detection algorithm

    NASA Astrophysics Data System (ADS)

    Chen, Yudong; Zhou, Wang

    2016-09-01

    Light projection method is often used in measuring system for wire diameter, which is relatively simpler structure and lower cost, and the measuring accuracy is limited by the pixel size of CCD. Using a CCD with small pixel size can improve the measuring accuracy, but will increase the cost and difficulty of making. In this paper, through the comparative analysis of a variety of sub-pixel edge detection algorithms, polynomial fitting method is applied for data processing in measuring system for wire diameter, to improve the measuring accuracy and enhance the ability of anti-noise. In the design of system structure, light projection method with orthogonal structure is used for the detection optical part, which can effectively reduce the error caused by line jitter in the measuring process. For the electrical part, ARM Cortex-M4 microprocessor is used as the core of the circuit module, which can not only drive double channel linear CCD but also complete the sampling, processing and storage of the CCD video signal. In addition, ARM microprocessor can complete the high speed operation of the whole measuring system for wire diameter in the case of no additional chip. The experimental results show that sub-pixel edge detection algorithm based on polynomial fitting can make up for the lack of single pixel size and improve the precision of measuring system for wire diameter significantly, without increasing hardware complexity of the entire system.

  20. A Portable Smart-Phone Readout Device for the Detection of Mercury Contamination Based on an Aptamer-Assay Nanosensor.

    PubMed

    Xiao, Wei; Xiao, Meng; Fu, Qiangqiang; Yu, Shiting; Shen, Haicong; Bian, Hongfen; Tang, Yong

    2016-11-08

    The detection of environmental mercury (Hg) contamination requires complex and expensive instruments and professional technicians. We present a simple, sensitive, and portable Hg 2+ detection system based on a smartphone and colorimetric aptamer nanosensor. A smartphone equipped with a light meter app was used to detect, record, and process signals from a smartphone-based microwell reader (MR S-phone), which is composed of a simple light source and a miniaturized assay platform. The colorimetric readout of the aptamer nanosensor is based on a specific interaction between the selected aptamer and Hg 2+ , which leads to a color change in the reaction solution due to an aggregation of gold nanoparticles (AuNPs). The MR S-phone-based AuNPs-aptamer colorimetric sensor system could reliably detect Hg 2+ in both tap water and Pearl River water samples and produced a linear colorimetric readout of Hg 2+ concentration in the range of 1 ng/mL-32 ng/mL with a correlation of 0.991, and a limit of detection (LOD) of 0.28 ng/mL for Hg 2+ . The detection could be quickly completed in only 20 min. Our novel mercury detection assay is simple, rapid, and sensitive, and it provides new strategies for the on-site detection of mercury contamination in any environment.

  1. A Portable Smart-Phone Readout Device for the Detection of Mercury Contamination Based on an Aptamer-Assay Nanosensor

    PubMed Central

    Xiao, Wei; Xiao, Meng; Fu, Qiangqiang; Yu, Shiting; Shen, Haicong; Bian, Hongfen; Tang, Yong

    2016-01-01

    The detection of environmental mercury (Hg) contamination requires complex and expensive instruments and professional technicians. We present a simple, sensitive, and portable Hg2+ detection system based on a smartphone and colorimetric aptamer nanosensor. A smartphone equipped with a light meter app was used to detect, record, and process signals from a smartphone-based microwell reader (MR S-phone), which is composed of a simple light source and a miniaturized assay platform. The colorimetric readout of the aptamer nanosensor is based on a specific interaction between the selected aptamer and Hg2+, which leads to a color change in the reaction solution due to an aggregation of gold nanoparticles (AuNPs). The MR S-phone-based AuNPs-aptamer colorimetric sensor system could reliably detect Hg2+ in both tap water and Pearl River water samples and produced a linear colorimetric readout of Hg2+ concentration in the range of 1 ng/mL–32 ng/mL with a correlation of 0.991, and a limit of detection (LOD) of 0.28 ng/mL for Hg2+. The detection could be quickly completed in only 20 min. Our novel mercury detection assay is simple, rapid, and sensitive, and it provides new strategies for the on-site detection of mercury contamination in any environment. PMID:27834794

  2. System and Method for Automated Rendezvous, Docking and Capture of Autonomous Underwater Vehicles

    NASA Technical Reports Server (NTRS)

    Clark, Evan (Inventor); Richmond, Kristof (Inventor); Paulus, Jeremy (Inventor); Kimball, Peter (Inventor); Scully, Mark (Inventor); Kapit, Jason (Inventor); Stone, William C. (Inventor)

    2018-01-01

    A system for automated rendezvous, docking, and capture of autonomous underwater vehicles at the conclusion of a mission comprising of comprised of a docking rod having lighted, pulsating (in both frequency and light intensity) series of LED light strips thereon, with the LEDs at a known spacing, and the autonomous underwater vehicle specially designed to detect and capture the docking rod and then be lifted structurally by a spherical end strop about which the vehicle can be pivoted and hoisted up (e.g., onto a ship). The method of recovery allows for very routine and reliable automated recovery of an unmanned underwater asset.

  3. Capillary-scale direct measurement of hemoglobin concentration of erythrocytes using photothermal angular light scattering.

    PubMed

    Kim, Uihan; Song, Jaewoo; Lee, Donghak; Ryu, Suho; Kim, Soocheol; Hwang, Jaehyun; Joo, Chulmin

    2015-12-15

    We present a direct, rapid and chemical-free detection method for hemoglobin concentration ([Hb]), based on photothermal angular light scattering. The iron oxides contained in hemoglobin molecules exhibit high absorption of 532-nm light and generate heat under the illumination of 532-nm light, which subsequently alters the refractive index of blood. We measured this photothermal change in refractive index by employing angular light scattering spectroscopy with the goal of quantifying [Hb] in blood samples. Highly sensitive [Hb] measurement of blood samples was performed by monitoring the shifts in angularly dispersed scattering patterns from the blood-loaded microcapillary tubes. Our system measured [Hb] over the range of 0.35-17.9 g/dL with a detection limit of ~0.12 g/dL. Our sensor was characterized by excellent correlation with a reference hematology analyzer (r>0.96), and yielded a precision of 0.63 g/dL for a blood sample of 9.0 g/dL. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Light-Addressed Electrodeposition of Enzyme-Entrapped Chitosan Membranes for Multiplexed Enzyme-Based Bioassays Using a Digital Micromirror Device

    PubMed Central

    Huang, Shih-Hao; Wei, Lu-Shiuan; Chu, Hsiao-Tzu; Jiang, Yeu-Long

    2013-01-01

    This paper describes a light-addressed electrolytic system used to perform an electrodeposition of enzyme-entrapped chitosan membranes for multiplexed enzyme-based bioassays using a digital micromirror device (DMD). In this system, a patterned light illumination is projected onto a photoconductive substrate serving as a photo-cathode to electrolytically produce hydroxide ions, which leads to an increased pH gradient. The high pH generated at the cathode can cause a local gelation of chitosan through sol-gel transition. By controlling the illumination pattern on the DMD, a light-addressed electrodeposition of chitosan membranes with different shapes and sizes, as well as multiplexed micropatterning, was performed. The effect of the illumination time of the light pattern on the dimensional resolution of chitosan membrane formation was examined experimentally. Moreover, multiplexed enzyme-based bioassay of enzyme-entrapped chitosan membranes was also successfully demonstrated through the electrodeposition of the chitosan membranes with various shapes/sizes and entrapping different enzymes. As a model experiment, glucose and ethanol were simultaneously detected in a single detection chamber without cross-talk using shape-coded chitosan membranes entrapped with glucose oxidase (GOX), peroxidase (POD), and Amplex Red (AmR) or alcohol oxidase (AOX), POD, and AmR by using same fluorescence indicator (AmR). PMID:23959236

  5. Light-addressed electrodeposition of enzyme-entrapped chitosan membranes for multiplexed enzyme-based bioassays using a digital micromirror device.

    PubMed

    Huang, Shih-Hao; Wei, Lu-Shiuan; Chu, Hsiao-Tzu; Jiang, Yeu-Long

    2013-08-16

    This paper describes a light-addressed electrolytic system used to perform an electrodeposition of enzyme-entrapped chitosan membranes for multiplexed enzyme-based bioassays using a digital micromirror device (DMD). In this system, a patterned light illumination is projected onto a photoconductive substrate serving as a photo-cathode to electrolytically produce hydroxide ions, which leads to an increased pH gradient. The high pH generated at the cathode can cause a local gelation of chitosan through sol-gel transition. By controlling the illumination pattern on the DMD, a light-addressed electrodeposition of chitosan membranes with different shapes and sizes, as well as multiplexed micropatterning, was performed. The effect of the illumination time of the light pattern on the dimensional resolution of chitosan membrane formation was examined experimentally. Moreover, multiplexed enzyme-based bioassay of enzyme-entrapped chitosan membranes was also successfully demonstrated through the electrodeposition of the chitosan membranes with various shapes/sizes and entrapping different enzymes. As a model experiment, glucose and ethanol were simultaneously detected in a single detection chamber without cross-talk using shape-coded chitosan membranes entrapped with glucose oxidase (GOX), peroxidase (POD), and Amplex Red (AmR) or alcohol oxidase (AOX), POD, and AmR by using same fluorescence indicator (AmR).

  6. Single-beam dielectric-microsphere trapping with optical heterodyne detection

    NASA Astrophysics Data System (ADS)

    Rider, Alexander D.; Blakemore, Charles P.; Gratta, Giorgio; Moore, David C.

    2018-01-01

    A technique to levitate and measure the three-dimensional position of micrometer-sized dielectric spheres with heterodyne detection is presented. The two radial degrees of freedom are measured by interfering light transmitted through the microsphere with a reference wavefront, while the axial degree of freedom is measured from the phase of the light reflected from the surface of the microsphere. This method pairs the simplicity and accessibility of single-beam optical traps to a measurement of displacement that is intrinsically calibrated by the wavelength of the trapping light and has exceptional immunity to stray light. A theoretical shot noise limit of 1.3 ×10-13 m /√{Hz } for the radial degrees of freedom, and 3.0 ×10-15 m /√{Hz } for the axial degree of freedom can be obtained in the system described. The measured acceleration noise in the radial direction is 7.5 ×10-5 (m /s2) /√{Hz } .

  7. Apparatuses for large area radiation detection and related method

    DOEpatents

    Akers, Douglas W; Drigert, Mark W

    2015-04-28

    Apparatuses and a related method relating to radiation detection are disclosed. In one embodiment, an apparatus includes a first scintillator and a second scintillator adjacent to the first scintillator, with each of the first scintillator and second scintillator being structured to generate a light pulse responsive to interacting with incident radiation. The first scintillator is further structured to experience full energy deposition of a first low-energy radiation, and permit a second higher-energy radiation to pass therethrough and interact with the second scintillator. The apparatus further includes a plurality of light-to-electrical converters operably coupled to the second scintillator and configured to convert light pulses generated by the first scintillator and the second scintillator into electrical signals. The first scintillator and the second scintillator exhibit at least one mutually different characteristic for an electronic system to determine whether a given light pulse is generated by the first scintillator or the second scintillator.

  8. Miniature Tunable Laser Spectrometer for Detection of a Trace Gas

    NASA Technical Reports Server (NTRS)

    Christensen, Lance E. (Inventor)

    2017-01-01

    An open-path laser spectrometer (OPLS) for measuring a concentration of a trace gas, the OPLS including an open-path multi-pass analysis region including a first mirror, a second mirror at a distance and orientation from the first mirror, and a support structure for locating the mirrors, a laser coupled to the analysis region and configured to emit light of a wavelength range and to enable a plurality of reflections of the emitted light between the mirrors, a detector coupled to the analysis region and configured to detect a portion of the emitted light impinging on the detector and to generate a corresponding signal, and an electronic system coupled to the laser and the detector, and configured to adjust the wavelength range of the emitted light from the laser based on the generated signal, and to measure the concentration of the trace gas based on the generated signal.

  9. Study of coherent reflectometer for imaging internal structures of highly scattering media

    NASA Astrophysics Data System (ADS)

    Poupardin, Mathieu; Dolfi, Agnes

    1996-01-01

    Optical reflectometers are potentially useful tools for imaging internal structures of turbid media, particularly of biological media. To get a point by point image, an active imaging system has to distinguish light scattered from a sample volume and light scattered by other locations in the media. Operating this discrimination of light with reflectometers based on coherence can be realized in two ways: assuring a geometric selection or a temporal selection. In this paper we present both methods, showing in each case the influence of the different parameters on the size of the sample volume under the assumption of single scattering. We also study the influence on the detection efficiency of the coherence loss of the incident light resulting from multiple scattering. We adapt a model, first developed for atmospheric lidar in turbulent atmosphere, to get an analytical expression of this detection efficiency in the function of the optical coefficients of the media.

  10. Development of a fast scintillator based beam phase measurement system for compact superconducting cyclotrons

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bhattacharjee, Tanushyam; Kanti Dey, Malay; Dhara, Partha

    2013-05-15

    In an isochronous cyclotron, measurements of central phase of the ion beam with respect to rf and the phase width provide a way to tune the cyclotron for maximum energy gain per turn and efficient extraction. We report here the development of a phase measurement system and the measurements carried out at the Variable Energy Cyclotron Centre's (VECC's) K= 500 superconducting cyclotron. The technique comprises detecting prompt {gamma}-rays resulting from the interaction of cyclotron ion beam with an aluminium target mounted on a radial probe in coincidence with cyclotron rf. An assembly comprising a fast scintillator and a liquid light-guidemore » inserted inside the cyclotron was used to detect the {gamma}-rays and to transfer the light signal outside the cyclotron where a matching photo-multiplier tube was used for light to electrical signal conversion. The typical beam intensity for this measurement was a few times 10{sup 11} pps.« less

  11. Dental calculus detection using the VistaCam.

    PubMed

    Shakibaie, Fardad; Walsh, Laurence J

    2016-12-01

    The VistaCam® intra-oral camera system (Dürr Dental, Bietigheim-Bissingen, Germany) is a fluorescence system using light emitting diodes that produce a 405-nm violet light. This wavelength has potential application for detection of dental calculus based on red emissions from porphyrin molecules. This study assessed the digital scores obtained for both supragingival and subgingival calculus on 60 extracted teeth and compared these with lesions of dental caries. It has also examined the effect of saliva and blood on the fluorescence readings for dental calculus. VistaCam fluorescence scores for both supragingival (1.7-3.3) and subgingival calculus (1.3-2.4) were higher than those for sound root surfaces (0.9-1.1) and dental caries (0.9-2.2) ( p  < .05). The readings for calculus samples were not affected by the presence of saliva or blood. These results suggest that the use of violet light fluorescence could be a possible adjunct to clinical examination for deposits of dental calculus.

  12. Photovoltaic-Pyroelectric Coupled Effect Induced Electricity for Self-Powered Photodetector System.

    PubMed

    Ma, Nan; Zhang, Kewei; Yang, Ya

    2017-12-01

    Ferroelectric materials have demonstrated novel photovoltaic effect to scavenge solar energy. However, most of the ferroelectric materials with wide bandgaps (2.7-4 eV) suffer from low power conversion efficiency of less than 0.5% due to absorbing only 8-20% of solar spectrum. Instead of harvesting solar energy, these ferroelectric materials can be well suited for photodetector applications, especially for sensing near-UV irradiations. Here, a ferroelectric BaTiO 3 film-based photodetector is demonstrated that can be operated without using any external power source and a fast sensing of 405 nm light illumination is enabled. As compared with photovoltaic effect, both the responsivity and the specific detectivity of the photodetector can be dramatically enhanced by larger than 260% due to the light-induced photovoltaic-pyroelectric coupled effect. A self-powered photodetector array system can be utilized to achieve spatially resolved light intensity detection by recording the output voltage signals as a mapping figure. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Portable dual field gradient force multichannel flow cytometer device with a dual wavelength low noise detection scheme

    DOEpatents

    James, Conrad D; Galambos, Paul C; Derzon, Mark S; Graf, Darin C; Pohl, Kenneth R; Bourdon, Chris J

    2012-10-23

    Systems and methods for combining dielectrophoresis, magnetic forces, and hydrodynamic forces to manipulate particles in channels formed on top of an electrode substrate are discussed. A magnet placed in contact under the electrode substrate while particles are flowing within the channel above the electrode substrate allows these three forces to be balanced when the system is in operation. An optical detection scheme using near-confocal microscopy for simultaneously detecting two wavelengths of light emitted from the flowing particles is also discussed.

  14. A portable system for noninvasive assessment of advanced glycation end-products using skin fluorescence and reflectance spectrum

    NASA Astrophysics Data System (ADS)

    Wang, Y. K.; Zhu, L.; Zhang, L.; Zhang, G.; Liu, Y.; Wang, A.

    2012-07-01

    An optical system has been developed for noninvasive assessment of skin advanced glycation end-products (AGEs). The system comprises mainly a high-power ultraviolet light emitting diode (LED) as an excitation source, an LED array for the reflectance measurement, a trifurcated fiber-optic probe for light transmitting and receiving, and a compact spectrometer for light detecting. Both skin fluorescence of a subject and the reflectance spectrum of the same site can be obtained in a single measurement with the system. Demonstrative measurements with the system have been conducted. Results indicate that the measured reflectance spectrum can be used to compensate for the distortion of AGEs fluorescence, which is caused by skin absorption and scattering. The system is noninvasive, portable, easy to operate, and has potential applications for clinical diagnosis of AGE-related diseases, especially diabetes mellitus.

  15. Feature selection from hyperspectral imaging for guava fruit defects detection

    NASA Astrophysics Data System (ADS)

    Mat Jafri, Mohd. Zubir; Tan, Sou Ching

    2017-06-01

    Development of technology makes hyperspectral imaging commonly used for defect detection. In this research, a hyperspectral imaging system was setup in lab to target for guava fruits defect detection. Guava fruit was selected as the object as to our knowledge, there is fewer attempts were made for guava defect detection based on hyperspectral imaging. The common fluorescent light source was used to represent the uncontrolled lighting condition in lab and analysis was carried out in a specific wavelength range due to inefficiency of this particular light source. Based on the data, the reflectance intensity of this specific setup could be categorized in two groups. Sequential feature selection with linear discriminant (LD) and quadratic discriminant (QD) function were used to select features that could potentially be used in defects detection. Besides the ordinary training method, training dataset in discriminant was separated in two to cater for the uncontrolled lighting condition. These two parts were separated based on the brighter and dimmer area. Four evaluation matrixes were evaluated which are LD with common training method, QD with common training method, LD with two part training method and QD with two part training method. These evaluation matrixes were evaluated using F1-score with total 48 defected areas. Experiment shown that F1-score of linear discriminant with the compensated method hitting 0.8 score, which is the highest score among all.

  16. A photodiode amplifier system for pulse-by-pulse intensity measurement of an x-ray free electron laser.

    PubMed

    Kudo, Togo; Tono, Kensuke; Yabashi, Makina; Togashi, Tadashi; Sato, Takahiro; Inubushi, Yuichi; Omodani, Motohiko; Kirihara, Yoichi; Matsushita, Tomohiro; Kobayashi, Kazuo; Yamaga, Mitsuhiro; Uchiyama, Sadayuki; Hatsui, Takaki

    2012-04-01

    We have developed a single-shot intensity-measurement system using a silicon positive-intrinsic-negative (PIN) photodiode for x-ray pulses from an x-ray free electron laser. A wide dynamic range (10(3)-10(11) photons/pulse) and long distance signal transmission (>100 m) were required for this measurement system. For this purpose, we developed charge-sensitive and shaping amplifiers, which can process charge pulses with a wide dynamic range and variable durations (ns-μs) and charge levels (pC-μC). Output signals from the amplifiers were transmitted to a data acquisition system through a long cable in the form of a differential signal. The x-ray pulse intensities were calculated from the peak values of the signals by a waveform fitting procedure. This system can measure 10(3)-10(9) photons/pulse of ~10 keV x-rays by direct irradiation of a silicon PIN photodiode, and from 10(7)-10(11) photons/pulse by detecting the x-rays scattered by a diamond film using the silicon PIN photodiode. This system gives a relative accuracy of ~10(-3) with a proper gain setting of the amplifiers for each measurement. Using this system, we succeeded in detecting weak light at the developmental phase of the light source, as well as intense light during lasing of the x-ray free electron laser. © 2012 American Institute of Physics

  17. 33 CFR 117.743 - Rahway River.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... lights anytime the bridge is not in the full open position. (d) An infrared sensor system shall be... the infrared sensor system. (g) If the infrared sensors detect a vessel or other obstruction.... (j) In the event of a failure, or obstruction to the infrared sensor system, the bridge shall...

  18. 33 CFR 117.743 - Rahway River.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... lights anytime the bridge is not in the full open position. (d) An infrared sensor system shall be... the infrared sensor system. (g) If the infrared sensors detect a vessel or other obstruction.... (j) In the event of a failure, or obstruction to the infrared sensor system, the bridge shall...

  19. 33 CFR 117.743 - Rahway River.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... lights anytime the bridge is not in the full open position. (d) An infrared sensor system shall be... the infrared sensor system. (g) If the infrared sensors detect a vessel or other obstruction.... (j) In the event of a failure, or obstruction to the infrared sensor system, the bridge shall...

  20. 33 CFR 117.743 - Rahway River.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... lights anytime the bridge is not in the full open position. (d) An infrared sensor system shall be... the infrared sensor system. (g) If the infrared sensors detect a vessel or other obstruction.... (j) In the event of a failure, or obstruction to the infrared sensor system, the bridge shall...

  1. 33 CFR 117.743 - Rahway River.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... lights anytime the bridge is not in the full open position. (d) An infrared sensor system shall be... the infrared sensor system. (g) If the infrared sensors detect a vessel or other obstruction.... (j) In the event of a failure, or obstruction to the infrared sensor system, the bridge shall...

  2. Optical Techniques for the Remote Detection of Biological Aerosols

    DTIC Science & Technology

    1974-08-01

    1) Laboratory exneriments (2) Remote detection experiments. In the first phase , the optical characteristics of several selected biological...the-art optical sensor system. The estimates were favorable, and a second research phase was initiated. Remote detection experiments were conducted...that of phase fluorometry. The fluorescence is excited by 3. continuous light source, the output of which is modulated at a high freeuency by an optical

  3. Design of the scanning mode coated glass color difference online detection system

    NASA Astrophysics Data System (ADS)

    Bi, Weihong; Zhang, Yu; Wang, Dajiang; Zhang, Baojun; Fu, Guangwei

    2008-03-01

    A design of scanning mode coated glass color difference online detection system was introduced. The system consisted of color difference data acquirement part and orbit control part. The function of the color difference data acquirement part was to acquire glass spectral reflectance and then processed them to get the color difference value. Using fiber for light guiding, the reflected light from surface of glass was transmitted into light division part, and the dispersive light was imaged on linear CCD, and then the output signals from the CCD was sampled pixel by pixel, and the spectral reflectance of coated glass was obtained finally. Then, the acquired spectral reflectance signals was sent to industrial personal computer through USB interface, using standard color space and color difference formula nominated by International Commission on Illumination (CIE) in 1976 to process these signals, and the reflected color parameter and color difference of coated glass was gained in the end. The function of the orbit control part was to move the detection probe by way of transverse scanning mode above the glass strip, and control the measuring start-stop time of the color difference data acquirement part at the same time. The color difference data acquirement part of the system was put on the orbit which is after annealing area in coated glass production line, and the protected fiber probe was placed on slide of the orbit. Using single chip microcomputer to control transmission mechanism of the slide, which made the slide move by way of transverse scanning mode on the glass strip, meanwhile, the color difference data acquirement part of the system was also controlled by the single chip microcomputer, and it made the acquirement part measure color difference data when the probe reached the needed working speed and required place on the glass strip. The scanning mode coated glass color difference online detection system can measure color parameter and color difference of each transverse point on glass strip, it can also measure lengthways color stability on glass strip. Furthermore, the measuring results can be transmitted to coated control room through intranet, so it is very useful to improve producing technique in time. In addition, equipping necessary marking machine, this system can classify glass board automatically based on the measuring result.

  4. Nonlinear Time-Variant Response in an Avalanche Photodiode Array Based Laser Detection and Ranging System

    DTIC Science & Technology

    2007-03-01

    the system is treated in a gray-box manner, with limited known parameters. The analytical approach which follows was used to identify the deviations be...effect spherical aberration, coma and astigmatism is to blur the image by introducing light from outside each pixel’s IFOV. Petzval field curvature and...difference between the two records is not the linear difference of the incident light levels. Even dark current subtraction must be treated with caution

  5. Hohlraum glint and laser pre-pulse detector for NIF experiments using velocity interferometer system for any reflector.

    PubMed

    Moody, J D; Clancy, T J; Frieders, G; Celliers, P M; Ralph, J; Turnbull, D P

    2014-11-01

    Laser pre-pulse and early-time laser reflection from the hohlraum wall onto the capsule (termed "glint") can cause capsule imprint and unwanted early-time shocks on indirect drive implosion experiments. In a minor modification to the existing velocity interferometer system for any reflector diagnostic on NIF a fast-response vacuum photodiode was added to detect this light. The measurements show evidence of laser pre-pulse and possible light reflection off the hohlraum wall and onto the capsule.

  6. 40 CFR 63.1007 - Pumps in light liquid service standards.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... sensor that indicates failure of the seal system, the barrier fluid system, or both. The owner or... reservoir that is routed to a process or fuel gas system or connected by a closed vent system to a control... liquid service. (iv) Each barrier fluid system is equipped with a sensor that will detect failure of the...

  7. 40 CFR 63.1007 - Pumps in light liquid service standards.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... sensor that indicates failure of the seal system, the barrier fluid system, or both. The owner or... reservoir that is routed to a process or fuel gas system or connected by a closed vent system to a control... liquid service. (iv) Each barrier fluid system is equipped with a sensor that will detect failure of the...

  8. 40 CFR 63.1026 - Pumps in light liquid service standards.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... presence and frequency of drips and to the sensor that indicates failure of the seal system, the barrier... or fuel gas system or connected by a closed-vent system to a control device that complies with the.... (iv) Each barrier fluid system is equipped with a sensor that will detect failure of the seal system...

  9. THE VERY EARLY LIGHT CURVE OF SN 2015F IN NGC 2442: A POSSIBLE DETECTION OF SHOCK-HEATED COOLING EMISSION AND CONSTRAINTS ON SN Ia PROGENITOR SYSTEM

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Im, Myungshin; Choi, Changsu; Kim, Jae-Woo

    2015-11-15

    The main progenitor candidates of Type Ia supernovae (SNe Ia) are white dwarfs in binary systems where the companion star is another white dwarf (double degenerate (DD) system) or a less-evolved, non-degenerate star with R{sub *} ≳ 0.1 R{sub ⊙} (single degenerate system). However, no direct observational evidence exists to tell us which progenitor system is more common. Recent studies suggest that the light curve of a supernova shortly after its explosion can be used to set a limit on the progenitor size, R{sub *}. Here, we report high-cadence monitoring observations of SN 2015F, a normal SN Ia in themore » galaxy NGC 2442, starting about 84 days before the first light time. Using our daily cadence data, we capture the emergence of the radioactively powered light curve; more importantly, with >97.4% confidence, we detect possible dim precursor emission that appears roughly 1.5 days before the rise of the radioactively powered emission. The signal is consistent with theoretical expectations for a progenitor system involving a companion star with R{sub *} ≃ 0.1–1 R{sub ⊙} or a prompt explosion of a DD system, but is inconsistent with the typically invoked size of a white dwarf progenitor of R{sub *} ∼ 0.01 R{sub ⊙}. Upper limits on the precursor emission also constrain the progenitor size to be R{sub *} ≲ 0.1 R{sub ⊙} with a companion star size of R{sub *} ≲ 1.0 R{sub ⊙}, excluding a very large companion star in the progenitor system. Additionally, we find that the distance to SN 2015F is 23.9 ± 0.4 Mpc.« less

  10. Structured light: theory and practice and practice and practice...

    NASA Astrophysics Data System (ADS)

    Keizer, Richard L.; Jun, Heesung; Dunn, Stanley M.

    1991-04-01

    We have developed a structured light system for noncontact 3-D measurement of human body surface areas and volumes. We illustrate the image processing steps and algorithms used to recover range data from a single camera image, reconstruct a complete surface from one or more sets of range data, and measure areas and volumes. The development of a working system required the solution to a number of practical problems in image processing and grid labeling (the stereo correspondence problem for structured light). In many instances we found that the standard cookbook techniques for image processing failed. This was due in part to the domain (human body), the restrictive assumptions of the models underlying the cookbook techniques, and the inability to consistently predict the outcome of the image processing operations. In this paper, we will discuss some of our successes and failures in two key steps in acquiring range data using structured light: First, the problem of detecting intersections in the structured light grid, and secondly, the problem of establishing correspondence between projected and detected intersections. We will outline the problems and solutions we have arrived at after several years of trial and error. We can now measure range data with an r.m.s. relative error of 0.3% and measure areas on the human body surface within 3% and volumes within 10%. We have found that the solution to building a working vision system requires the right combination of theory and experimental verification.

  11. Deterministically Entangling Two Remote Atomic Ensembles via Light-Atom Mixed Entanglement Swapping

    PubMed Central

    Liu, Yanhong; Yan, Zhihui; Jia, Xiaojun; Xie, Changde

    2016-01-01

    Entanglement of two distant macroscopic objects is a key element for implementing large-scale quantum networks consisting of quantum channels and quantum nodes. Entanglement swapping can entangle two spatially separated quantum systems without direct interaction. Here we propose a scheme of deterministically entangling two remote atomic ensembles via continuous-variable entanglement swapping between two independent quantum systems involving light and atoms. Each of two stationary atomic ensembles placed at two remote nodes in a quantum network is prepared to a mixed entangled state of light and atoms respectively. Then, the entanglement swapping is unconditionally implemented between the two prepared quantum systems by means of the balanced homodyne detection of light and the feedback of the measured results. Finally, the established entanglement between two macroscopic atomic ensembles is verified by the inseparability criterion of correlation variances between two anti-Stokes optical beams respectively coming from the two atomic ensembles. PMID:27165122

  12. Immunoglobulin light chain allelic inclusion in systemic lupus erythematosus

    PubMed Central

    Fraser, Louise D.; Zhao, Yuan; Lutalo, Pamela M. K.; D'Cruz, David P.; Cason, John; Silva, Joselli S.; Dunn‐Walters, Deborah K.; Nayar, Saba; Cope, Andrew P.

    2015-01-01

    The principles of allelic exclusion state that each B cell expresses a single light and heavy chain pair. Here, we show that B cells with both kappa and lambda light chains (Igκ and Igλ) are enriched in some patients with the systemic autoimmune disease systemic lupus erythematosus (SLE), but not in the systemic autoimmune disease control granulomatosis with polyangiitis. Detection of dual Igκ and Igλ expression by flow cytometry could not be abolished by acid washing or by DNAse treatment to remove any bound polyclonal antibody or complexes, and was retained after two days in culture. Both surface and intracytoplasmic dual light chain expression was evident by flow cytometry and confocal microscopy. We observed reduced frequency of rearrangements of the kappa‐deleting element (KDE) in SLE and an inverse correlation between the frequency of KDE rearrangement and the frequency of dual light chain expressing B cells. We propose that dual expression of Igκ and Igλ by a single B cell may occur in some patients with SLE when this may be a consequence of reduced activity of the KDE. PMID:26036683

  13. Low-intensity calibration source for optical imaging systems

    NASA Astrophysics Data System (ADS)

    Holdsworth, David W.

    2017-03-01

    Laboratory optical imaging systems for fluorescence and bioluminescence imaging have become widely available for research applications. These systems use an ultra-sensitive CCD camera to produce quantitative measurements of very low light intensity, detecting signals from small-animal models labeled with optical fluorophores or luminescent emitters. Commercially available systems typically provide quantitative measurements of light output, in units of radiance (photons s-1 cm-2 SR-1) or intensity (photons s-1 cm-2). One limitation to current systems is that there is often no provision for routine quality assurance and performance evaluation. We describe such a quality assurance system, based on an LED-illuminated thin-film transistor (TFT) liquid-crystal display module. The light intensity is controlled by pulse-width modulation of the backlight, producing radiance values ranging from 1.8 x 106 photons s-1 cm-2 SR-1 to 4.2 x 1013 photons s-1 cm-2 SR-1. The lowest light intensity values are produced by very short backlight pulses (i.e. approximately 10 μs), repeated every 300 s. This very low duty cycle is appropriate for laboratory optical imaging systems, which typically operate with long-duration exposures (up to 5 minutes). The low-intensity light source provides a stable, traceable radiance standard that can be used for routine quality assurance of laboratory optical imaging systems.

  14. Objective-lens-free Fiber-based Position Detection with Nanometer Resolution in a Fiber Optical Trapping System.

    PubMed

    Ti, Chaoyang; Ho-Thanh, Minh-Tri; Wen, Qi; Liu, Yuxiang

    2017-10-13

    Position detection with high accuracy is crucial for force calibration of optical trapping systems. Most existing position detection methods require high-numerical-aperture objective lenses, which are bulky, expensive, and difficult to miniaturize. Here, we report an affordable objective-lens-free, fiber-based position detection scheme with 2 nm spatial resolution and 150 MHz bandwidth. This fiber based detection mechanism enables simultaneous trapping and force measurements in a compact fiber optical tweezers system. In addition, we achieved more reliable signal acquisition with less distortion compared with objective based position detection methods, thanks to the light guiding in optical fibers and small distance between the fiber tips and trapped particle. As a demonstration of the fiber based detection, we used the fiber optical tweezers to apply a force on a cell membrane and simultaneously measure the cellular response.

  15. Slow-light enhanced subwavelength plasmonic waveguide refractive index sensors.

    PubMed

    Huang, Yin; Min, Changjun; Dastmalchi, Pouya; Veronis, Georgios

    2015-06-01

    We introduce slow-light enhanced subwavelength scale refractive index sensors which consist of a plasmonic metal-dielectric-metal (MDM) waveguide based slow-light system sandwiched between two conventional MDM waveguides. We first consider a MDM waveguide with small width structrue for comparison, and then consider two MDM waveguide based slow light systems: a MDM waveguide side-coupled to arrays of stub resonators system and a MDM waveguide side-coupled to arrays of double-stub resonators system. We find that, as the group velocity decreases, the sensitivity of the effective index of the waveguide mode to variations of the refractive index of the fluid filling the sensors as well as the sensitivities of the reflection and transmission coefficients of the waveguide mode increase. The sensing characteristics of the slow-light waveguide based sensor structures are systematically analyzed. We show that the slow-light enhanced sensors lead to not only 3.9 and 3.5 times enhancements in the refractive index sensitivity, and therefore in the minimum detectable refractive index change, but also to 2 and 3 times reductions in the required sensing length, respectively, compared to a sensor using a MDM waveguide with small width structure.

  16. Ring-Resonator/Sol-Gel Interferometric Immunosensor

    NASA Technical Reports Server (NTRS)

    Bearman, Gregory; Cohen, David

    2007-01-01

    A proposed biosensing system would be based on a combination of (1) a sensing volume containing antibodies immobilized in a sol-gel matrix and (2) an optical interferometer having a ring resonator configuration. The antibodies would be specific to an antigen species that one seeks to detect. In the ring resonator of the proposed system, light would make multiple passes through the sensing volume, affording greater interaction length and, hence, greater antibody- detection sensitivity.

  17. Detection of hidden explosives by using tagged neutron beams: Status and perspectives

    NASA Astrophysics Data System (ADS)

    Viesti, Giuseppe; Pesente, Silvia; Nebbia, Giancarlo; Lunardon, Marcello; Sudac, Davorin; Nađ, Karlo; Blagus, Sasha; Valković, Vladivoj

    2005-12-01

    Non-destructive inspections have been simulated in laboratory conditions by using our tagged neutron inspection system (TNIS), using YAP:Ce scintillators to tag the neutron beam and an array of BaF2 crystals to detect the γ-rays. The system has been operated up to 2 × 108 neutron/s. Further developments of the TNIS concept are discussed in the light of our current projects for cargo container inspections.

  18. SEVEN NEW BINARIES DISCOVERED IN THE KEPLER LIGHT CURVES THROUGH THE BEER METHOD CONFIRMED BY RADIAL-VELOCITY OBSERVATIONS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Faigler, S.; Mazeh, T.; Tal-Or, L.

    We present seven newly discovered non-eclipsing short-period binary systems with low-mass companions, identified by the recently introduced BEER algorithm, applied to the publicly available 138-day photometric light curves obtained by the Kepler mission. The detection is based on the beaming effect (sometimes called Doppler boosting), which increases (decreases) the brightness of any light source approaching (receding from) the observer, enabling a prediction of the stellar Doppler radial-velocity (RV) modulation from its precise photometry. The BEER algorithm identifies the BEaming periodic modulation, with a combination of the well-known Ellipsoidal and Reflection/heating periodic effects, induced by short-period companions. The seven detections weremore » confirmed by spectroscopic RV follow-up observations, indicating minimum secondary masses in the range 0.07-0.4 M{sub Sun }. The binaries discovered establish for the first time the feasibility of the BEER algorithm as a new detection method for short-period non-eclipsing binaries, with the potential to detect in the near future non-transiting brown-dwarf secondaries, or even massive planets.« less

  19. Genetically modified plants for tactical systems applications

    NASA Astrophysics Data System (ADS)

    Stewart, C. Neal, Jr.

    2002-08-01

    Plants are ubiquitous in the environment and have the ability to respond to their environment physiologically and through altered gene expression profiles (they cannot walk away). In addition, plant genetic transformation techniques and genomic information in plants are becoming increasingly advanced. We have been performing research to express the jellyfish green fluorescent protein (GFP) in plants. GFP emits green light when excited by blue or UV light. In addition, my group and collaborators have developed methods to detect GFP in plants by contact instruments and at a standoff. There are several tactical uses for this technology. Some obvious applications are using plants as sentinels for detecting biological and chemical warfare agents or their derivatives from a remote platform, as well as detecting explosives. Another tactical application is covert monitoring using individual plants. Different methods to detect GFP in transgenic plants will be discussed.

  20. Directional imaging of the retinal cone mosaic

    NASA Astrophysics Data System (ADS)

    Vohnsen, Brian; Iglesias, Ignacio; Artal, Pablo

    2004-05-01

    We describe a near-IR scanning laser ophthalmoscope that allows the retinal cone mosaic to be imaged in the human eye in vivo without the use of wave-front correction techniques. The method takes advantage of the highly directional quality of cone photoreceptors that permits efficient coupling of light to individual cones and subsequent detection of most directional components of the backscattered light produced by the light-guiding effect of the cones. We discuss details of the system and describe cone-mosaic images obtained under different conditions.

  1. Low Voltage Low Light Imager and Photodetector

    NASA Technical Reports Server (NTRS)

    Nikzad, Shouleh (Inventor); Martin, Chris (Inventor); Hoenk, Michael E. (Inventor)

    2013-01-01

    Highly efficient, low energy, low light level imagers and photodetectors are provided. In particular, a novel class of Della-Doped Electron Bombarded Array (DDEBA) photodetectors that will reduce the size, mass, power, complexity, and cost of conventional imaging systems while improving performance by using a thinned imager that is capable of detecting low-energy electrons, has high gain, and is of low noise.

  2. Optical leak detection of oxygen using IR-laser diodes

    NASA Technical Reports Server (NTRS)

    Disimile, P. J.; Fox, C.; Toy, N.

    1991-01-01

    The ability to accurately measure the concentration of gaseous oxygen and its corresponding flow rate is becoming of greater importance. The technique being presented is based on the principal of light attenuation due to the absorption of radiation by the A-band of oxygen which is located in the 759-770 nm wavelength range. With an ability to measure the change in the light transmission to 0.05 percent, a sensitive optical leak detection system which has a rapid time response is possible. In this research program, the application of laser diode technology and its ability to be temperature tuned to a selected oxygen absorption spectral peak has allowed oxygen concentrations as low as 16,000 ppm to be detected.

  3. Optimal pulse design for communication-oriented slow-light pulse detection.

    PubMed

    Stenner, Michael D; Neifeld, Mark A

    2008-01-21

    We present techniques for designing pulses for linear slow-light delay systems which are optimal in the sense that they maximize the signal-to-noise ratio (SNR) and signal-to-noise-plus-interference ratio (SNIR) of the detected pulse energy. Given a communication model in which input pulses are created in a finite temporal window and output pulse energy in measured in a temporally-offset output window, the SNIR-optimal pulses achieve typical improvements of 10 dB compared to traditional pulse shapes for a given output window offset. Alternatively, for fixed SNR or SNIR, window offset (detection delay) can be increased by 0.3 times the window width. This approach also invites a communication-based model for delay and signal fidelity.

  4. OTDR fiber-optical chemical sensor system for detection and location of hydrocarbon leakage.

    PubMed

    Buerck, J; Roth, S; Kraemer, K; Mathieu, H

    2003-08-15

    A distributed sensing system for apolar hydrocarbons is presented which is built from a polymer-clad silica fiber adapted to an optical time domain reflectometer (OTDR) set-up. OTDR measurements allow locating and detecting chemicals by measuring the time delay between short light pulses entering the fiber and discrete changes in the backscatter signals that are caused by local extraction of hydrocarbons into the fiber cladding. The light guiding properties of the fiber are affected by interaction of the extracted chemicals with the evanescent wave light field extending into the fiber cladding. Distributed sensing of pure liquid hydrocarbons (HC) and aqueous HC solutions with a commercially available mini-OTDR adapted to sensing fibers of up to 1km length could be demonstrated. A pulsed laser diode emitting at the 850 nm telecommunication wavelength was applied in the mini-OTDR to locate the HCs by analyzing the step drop (light loss) in the backscatter signal, which is induced by local refractive index (RI) increase in the silicone cladding due to the extracted HC. The prototype instrument can be applied for monitoring hydrocarbon leakage in large technical installations, such as tanks, chemical pipelines or chemical waste disposal containments.

  5. Color Correction Parameter Estimation on the Smartphone and Its Application to Automatic Tongue Diagnosis.

    PubMed

    Hu, Min-Chun; Cheng, Ming-Hsun; Lan, Kun-Chan

    2016-01-01

    An automatic tongue diagnosis framework is proposed to analyze tongue images taken by smartphones. Different from conventional tongue diagnosis systems, our input tongue images are usually in low resolution and taken under unknown lighting conditions. Consequently, existing tongue diagnosis methods cannot be directly applied to give accurate results. We use the SVM (support vector machine) to predict the lighting condition and the corresponding color correction matrix according to the color difference of images taken with and without flash. We also modify the state-of-the-art work of fur and fissure detection for tongue images by taking hue information into consideration and adding a denoising step. Our method is able to correct the color of tongue images under different lighting conditions (e.g. fluorescent, incandescent, and halogen illuminant) and provide a better accuracy in tongue features detection with less processing complexity than the prior work. In this work, we proposed an automatic tongue diagnosis framework which can be applied to smartphones. Unlike the prior work which can only work in a controlled environment, our system can adapt to different lighting conditions by employing a novel color correction parameter estimation scheme.

  6. The design of infrared information collection circuit based on embedded technology

    NASA Astrophysics Data System (ADS)

    Liu, Haoting; Zhang, Yicong

    2013-07-01

    S3C2410 processor is a 16/32 bit RISC embedded processor which based on ARM920T core and AMNA bus, and mainly for handheld devices, and high cost, low-power applications. This design introduces a design plan of the PIR sensor system, circuit and its assembling, debugging. The Application Circuit of the passive PIR alarm uses the invisibility of the infrared radiation well into the alarm system, and in order to achieve the anti-theft alarm and security purposes. When the body goes into the range of PIR sensor detection, sensors will detect heat sources and then the sensor will output a weak signal. The Signal should be amplified, compared and delayed; finally light emitting diodes emit light, playing the role of a police alarm.

  7. Quantum hacking on quantum key distribution using homodyne detection

    NASA Astrophysics Data System (ADS)

    Huang, Jing-Zheng; Kunz-Jacques, Sébastien; Jouguet, Paul; Weedbrook, Christian; Yin, Zhen-Qiang; Wang, Shuang; Chen, Wei; Guo, Guang-Can; Han, Zheng-Fu

    2014-03-01

    Imperfect devices in commercial quantum key distribution systems open security loopholes that an eavesdropper may exploit. An example of one such imperfection is the wavelength-dependent coupling ratio of the fiber beam splitter. Utilizing this loophole, the eavesdropper can vary the transmittances of the fiber beam splitter at the receiver's side by inserting lights with wavelengths different from what is normally used. Here, we propose a wavelength attack on a practical continuous-variable quantum key distribution system using homodyne detection. By inserting light pulses at different wavelengths, this attack allows the eavesdropper to bias the shot-noise estimation even if it is done in real time. Based on experimental data, we discuss the feasibility of this attack and suggest a prevention scheme by improving the previously proposed countermeasures.

  8. Hardware-in-the-loop projector system for light detection and ranging sensor testing

    NASA Astrophysics Data System (ADS)

    Kim, Hajin J.; Naumann, Charles B.; Cornell, Michael C.

    2012-08-01

    Efforts in developing a synthetic environment for testing light detection and ranging (LADAR) sensors in a hardware-in-the-loop simulation are continuing at the Aviation and Missile Research, Engineering, and Development Center of the U.S. Army Research, Engineering and Development Command (RDECOM). Current activities have concentrated on evaluating the optical projection techniques for the LADAR synthetic environment. Schemes for generating the optical signals representing the individual pixels of the projection are of particular interest. Several approaches have been investigated and tested with emphasis on operating wavelength, intensity dynamic range and uniformity, and flexibility in pixel waveform generation. This paper will discuss some of the results from these current efforts at RDECOM's System Simulation and Development Directorate's Electro Optical Technology Development Laboratory.

  9. Wide-angle imaging system with fiberoptic components providing angle-dependent virtual material stops

    NASA Technical Reports Server (NTRS)

    Vaughan, Arthur H. (Inventor)

    1993-01-01

    A strip imaging wide angle optical system is provided. The optical system is provided with a 'virtual' material stop to avoid aberrational effects inherent in wide angle optical systems. The optical system includes a spherical mirror section for receiving light from a 180 deg strip or arc of a target image. Light received by the spherical mirror section is reflected to a frustoconical mirror section for subsequent rereflection to a row of optical fibers. Each optical fiber transmits a portion of the received light to a detector. The optical system exploits the narrow cone of acceptance associated with optical fibers to substantially eliminate vignetting effects inherent in wide angle systems. Further, the optical system exploits the narrow cone of acceptance of the optical fibers to substantially limit spherical aberration. The optical system is ideally suited for any application wherein a 180 deg strip image need be detected, and is particularly well adapted for use in hostile environments such as in planetary exploration.

  10. Wide field strip-imaging optical system

    NASA Technical Reports Server (NTRS)

    Vaughan, Arthur H. (Inventor)

    1994-01-01

    A strip imaging wide angle optical system is provided. The optical system is provided with a 'virtual' material stop to avoid aberrational effects inherent in wide angle optical systems. The optical system includes a spherical mirror section for receiving light from a 180-degree strip or arc of a target image. Light received by the spherical mirror section is reflected to a frusto-conical mirror section for subsequent rereflection to a row of optical fibers. Each optical fiber transmits a portion of the received light to a detector. The optical system exploits the narrow cone of acceptance associated with optical fibers to substantially eliminate vignetting effects inherent in wide-angle systems. Further, the optical system exploits the narrow cone of acceptance of the optical fibers to substantially limit spherical aberration. The optical system is ideally suited for any application wherein a 180-degree strip image need be detected, and is particularly well adapted for use in hostile environments such as in planetary exploration.

  11. Fiber optic sensor based on reflectivity configurations to detect heart rate

    NASA Astrophysics Data System (ADS)

    Yunianto, M.; Marzuki, A.; Riyatun, R.; Lestari, D.

    2016-11-01

    Research of optical fiber-based heart rate detection sensor has been conducted using the reflection configurationon the thorax motion modified. Optical fiber used in this research was Plastic Optical Fiber (POF) with a diameter of 0.5. Optical fiber system is made with two pieces of fiber, the first fiber is to serve as a transmitter transmitting light from the source to the reflector membrane, the second fiber serves as a receiver. One of the endsfrom the two fibersis pressed and positioned perpendicular of reflector membrane which is placed on the surface of the chest. The sensor works on the principle of intensity changes captured by the receiver fiber when the reflector membrane gets the vibe from the heart. The light source used is in the form of Light Emitting Diode (LED) and Light Dependent Resistor (LDR) as a light sensor. Variations are performed on the reflector membrane diameter. The light intensity received by the detector increases along with the increasing width of the reflector membrane diameter. The results show that this sensor can detect the harmonic peak at a frequency of 1.5 Hz; 7.5 Hz; 10.5 Hz; and 22.5 Hz in a healthy human heart with an average value of Beat Per Minute (BPM) by 78 times, a prototype sensor that is made can work and function properly.

  12. Research on capability of detecting ballistic missile by near space infrared system

    NASA Astrophysics Data System (ADS)

    Lu, Li; Sheng, Wen; Jiang, Wei; Jiang, Feng

    2018-01-01

    The infrared detection technology of ballistic missile based on near space platform can effectively make up the shortcomings of high-cost of traditional early warning satellites and the limited earth curvature of ground-based early warning radar. In terms of target detection capability, aiming at the problem that the formula of the action distance based on contrast performance ignores the background emissivity in the calculation process and the formula is only valid for the monochromatic light, an improved formula of the detecting range based on contrast performance is proposed. The near space infrared imaging system parameters are introduced, the expression of the contrastive action distance formula based on the target detection of the near space platform is deduced. The detection range of the near space infrared system for the booster stage ballistic missile skin, the tail nozzle and the tail flame is calculated. The simulation results show that the near-space infrared system has the best effect on the detection of tail-flame radiation.

  13. Covert laser remote sensing and vibrometry

    NASA Technical Reports Server (NTRS)

    Maleki, Lutfollah (Inventor); Yu, Nan (Inventor); Matsko, Andrey B. (Inventor); Savchenkov, Anatoliy (Inventor)

    2012-01-01

    Designs of single-beam laser vibrometry systems and methods. For example, a method for detecting vibrations of a target based on optical sensing is provided to include operating a laser to produce a laser probe beam at a laser frequency and modulated at a modulation frequency onto a target; collecting light at or near the laser to collect light from the target while the target is being illuminated by the laser probe beam through an optical receiver aperture; using a narrow-band optical filter centered at the laser frequency to filter light collected from the optical receiver aperture to transmit light at the laser frequency while blocking light at other frequencies; using an optical detector to convert filtered light from the narrow-band optical filter to produce a receiver electrical signal; using a lock-in amplifier to detect and amplify the receiver electrical signal at the modulation frequency while rejecting signal components at other frequencies to produce an amplified receiver electrical signal; processing the amplified receiver electrical signal to extract information on vibrations of the target carried by reflected laser probe beam in the collected light; and controlling optical power of the laser probe beam at the target to follow optical power of background illumination at the target.

  14. A single step reversed-phase high performance liquid chromatography separation of polar and non-polar lipids.

    PubMed

    Olsson, Petter; Holmbäck, Jan; Herslöf, Bengt

    2014-11-21

    This paper reports a simple chromatographic system to separate lipids classes as well as their molecular species. By the use of phenyl coated silica as stationary phase in combination with a simple mobile phase consisting of methanol and water, all tested lipid classes elute within 30 min. Furthermore, a method to accurately predict retention times of specific lipid components for this type of chromatography is presented. Common detection systems were used, namely evaporative light scattering detection (ELSD), charged aerosol detection (CAD), electrospray mass spectrometry (ESI-MS), and UV detection. Copyright © 2014 Elsevier B.V. All rights reserved.

  15. A Practical Guide to Experimental Geometrical Optics

    NASA Astrophysics Data System (ADS)

    Garbovskiy, Yuriy A.; Glushchenko, Anatoliy V.

    2017-12-01

    Preface; 1. Markets of optical materials, components, accessories, light sources and detectors; 2. Introduction to optical experiments: light producing, light managing, light detection and measuring; 3. Light detectors based on semiconductors: photoresistors, photodiodes in a photo-galvanic regime. Principles of operation and measurements; 4. Linear light detectors based on photodiodes; 5. Basic laws of geometrical optics: experimental verification; 6. Converging and diverging thin lenses; 7. Thick lenses; 8. Lens systems; 9. Simple optical instruments I: the eye and the magnifier, eyepieces and telescopes; 10. Simple optical instruments II: light illuminators and microscope; 11. Spherical mirrors; 12. Introduction to optical aberrations; 13. Elements of optical radiometry; 14. Cylindrical lenses and vials; 15. Methods of geometrical optics to measure refractive index; 16. Dispersion of light and prism spectroscope; 17. Elements of computer aided optical design; Index.

  16. Polar nephelometer for atmospheric particulate studies

    NASA Technical Reports Server (NTRS)

    Hansen, M. Z.; Evans, W. H.

    1980-01-01

    A polar nephelometer for use in studying atmospheric aerosols was developed. The nephelometer detects molecular scatter from air and measures scattering from very clean air using pure molecular scattering for calibration. A compact system using a folded light path with an air cooled argon laser for the light source was designed. A small, sensitive detector unit permits easy angular rotation for changing the scattering angle. A narrow detector field of view of + or - 1/4 degree of scattering along with a single wavelength of incident light is used to minimize uncertainties in the scattering theory. The system is automated for data acquisition of the scattering matrix elements over an angular range from 2 degrees to 178 degrees of scattering. Both laser output and detector sensitivity are monitored to normalize the measured light scattering.

  17. Whole-body ring-shaped confocal photoacoustic computed tomography of small animals in vivo.

    PubMed

    Xia, Jun; Chatni, Muhammad R; Maslov, Konstantin; Guo, Zijian; Wang, Kun; Anastasio, Mark; Wang, Lihong V

    2012-05-01

    We report a novel small-animal whole-body imaging system called ring-shaped confocal photoacoustic computed tomography (RC-PACT). RC-PACT is based on a confocal design of free-space ring-shaped light illumination and 512-element full-ring ultrasonic array signal detection. The free-space light illumination maximizes the light delivery efficiency, and the full-ring signal detection ensures a full two-dimensional view aperture for accurate image reconstruction. Using cylindrically focused array elements, RC-PACT can image a thin cross section with 0.10 to 0.25 mm in-plane resolutions and 1.6  s/frame acquisition time. By translating the mouse along the elevational direction, RC-PACT provides a series of cross-sectional images of the brain, liver, kidneys, and bladder.

  18. Whole-body ring-shaped confocal photoacoustic computed tomography of small animals in vivo

    NASA Astrophysics Data System (ADS)

    Xia, Jun; Chatni, Muhammad R.; Maslov, Konstantin; Guo, Zijian; Wang, Kun; Anastasio, Mark; Wang, Lihong V.

    2012-05-01

    We report a novel small-animal whole-body imaging system called ring-shaped confocal photoacoustic computed tomography (RC-PACT). RC-PACT is based on a confocal design of free-space ring-shaped light illumination and 512-element full-ring ultrasonic array signal detection. The free-space light illumination maximizes the light delivery efficiency, and the full-ring signal detection ensures a full two-dimensional view aperture for accurate image reconstruction. Using cylindrically focused array elements, RC-PACT can image a thin cross section with 0.10 to 0.25 mm in-plane resolutions and 1.6 s/frame acquisition time. By translating the mouse along the elevational direction, RC-PACT provides a series of cross-sectional images of the brain, liver, kidneys, and bladder.

  19. Fluorescent fiber diagnostics

    DOEpatents

    Toeppen, John S.

    1994-10-04

    A fluorescent fiber (13) having a doped core (16) is pumped (11) by light (18) of a relatively short wavelength to produce fluorescence at a longer wavelength that is detected by detector (24). The level of fluorescence is monitored (26) and evaluated to provide information as to the excitation of the fiber (13) or the environment thereof. In particular, the level of intensity of the detected fluorescence may be used to measure the intensity of a light beam (18) passing axially through an optical fiber system (12) (FIG. 1 ), or the intensity of a light beam (46) passing radially through a fluorescent fiber (13) (FIG. 2 ), or the level of a fluid (32) in a tank (31) (FIG. 3 ), or a scintillation event (37) in a fluorescent fiber (13) pumped to produce amplification of the scintillation event (FIG. 4 ).

  20. Fluorescent fiber diagnostics

    DOEpatents

    Toeppen, John S.

    1994-01-01

    A fluorescent fiber (13) having a doped core (16) is pumped (11) by light (18) of a relatively short wavelength to produce fluorescence at a longer wavelength that is detected by detector (24). The level of fluorescence is monitored (26) and evaluated to provide information as to the excitation of the fiber (13) or the environment thereof. In particular, the level of intensity of the detected fluorescence may be used to measure the intensity of a light beam (18) passing axially through an optical fiber system (12) (FIG. 1 ), or the intensity of a light beam (46) passing radially through a fluorescent fiber (13) (FIG. 2 ), or the level of a fluid (32) in a tank (31) (FIG. 3 ), or a scintillation event (37) in a fluorescent fiber (13) pumped to produce amplification of the scintillation event (FIG. 4 ).

  1. Note: Three wavelengths near-infrared spectroscopy system for compensating the light absorbance by water

    NASA Astrophysics Data System (ADS)

    Bhutta, M. Raheel; Hong, Keum-Shik; Kim, Beop-Min; Hong, Melissa Jiyoun; Kim, Yun-Hee; Lee, Se-Ho

    2014-02-01

    Given that approximately 80% of blood is water, we develop a wireless functional near-infrared spectroscopy system that detects not only the concentration changes of oxy- and deoxy-hemoglobin (HbO and HbR) during mental activity but also that of water (H2O). Additionally, it implements a water-absorption correction algorithm that improves the HbO and HbR signal strengths during an arithmetic task. The system comprises a microcontroller, an optical probe, tri-wavelength light emitting diodes, photodiodes, a WiFi communication module, and a battery. System functionality was tested by means of arithmetic-task experiments performed by healthy male subjects.

  2. Note: three wavelengths near-infrared spectroscopy system for compensating the light absorbance by water.

    PubMed

    Bhutta, M Raheel; Hong, Keum-Shik; Kim, Beop-Min; Hong, Melissa Jiyoun; Kim, Yun-Hee; Lee, Se-Ho

    2014-02-01

    Given that approximately 80% of blood is water, we develop a wireless functional near-infrared spectroscopy system that detects not only the concentration changes of oxy- and deoxy-hemoglobin (HbO and HbR) during mental activity but also that of water (H2O). Additionally, it implements a water-absorption correction algorithm that improves the HbO and HbR signal strengths during an arithmetic task. The system comprises a microcontroller, an optical probe, tri-wavelength light emitting diodes, photodiodes, a WiFi communication module, and a battery. System functionality was tested by means of arithmetic-task experiments performed by healthy male subjects.

  3. SERODS optical data storage with parallel signal transfer

    DOEpatents

    Vo-Dinh, Tuan

    2003-09-02

    Surface-enhanced Raman optical data storage (SERODS) systems having increased reading and writing speeds, that is, increased data transfer rates, are disclosed. In the various SERODS read and write systems, the surface-enhanced Raman scattering (SERS) data is written and read using a two-dimensional process called parallel signal transfer (PST). The various embodiments utilize laser light beam excitation of the SERODS medium, optical filtering, beam imaging, and two-dimensional light detection. Two- and three-dimensional SERODS media are utilized. The SERODS write systems employ either a different laser or a different level of laser power.

  4. SERODS optical data storage with parallel signal transfer

    DOEpatents

    Vo-Dinh, Tuan

    2003-06-24

    Surface-enhanced Raman optical data storage (SERODS) systems having increased reading and writing speeds, that is, increased data transfer rates, are disclosed. In the various SERODS read and write systems, the surface-enhanced Raman scattering (SERS) data is written and read using a two-dimensional process called parallel signal transfer (PST). The various embodiments utilize laser light beam excitation of the SERODS medium, optical filtering, beam imaging, and two-dimensional light detection. Two- and three-dimensional SERODS media are utilized. The SERODS write systems employ either a different laser or a different level of laser power.

  5. Traffic Light Detection Using Conic Section Geometry

    NASA Astrophysics Data System (ADS)

    Hosseinyalmdary, S.; Yilmaz, A.

    2016-06-01

    Traffic lights detection and their state recognition is a crucial task that autonomous vehicles must reliably fulfill. Despite scientific endeavors, it still is an open problem due to the variations of traffic lights and their perception in image form. Unlike previous studies, this paper investigates the use of inaccurate and publicly available GIS databases such as OpenStreetMap. In addition, we are the first to exploit conic section geometry to improve the shape cue of the traffic lights in images. Conic section also enables us to estimate the pose of the traffic lights with respect to the camera. Our approach can detect multiple traffic lights in the scene, it also is able to detect the traffic lights in the absence of prior knowledge, and detect the traffics lights as far as 70 meters. The proposed approach has been evaluated for different scenarios and the results show that the use of stereo cameras significantly improves the accuracy of the traffic lights detection and pose estimation.

  6. A novel automated instrument designed to determine photosensitivity thresholds (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Aguilar, Mariela C.; Gonzalez, Alex; Rowaan, Cornelis; De Freitas, Carolina; Rosa, Potyra R.; Alawa, Karam; Lam, Byron L.; Parel, Jean-Marie A.

    2016-03-01

    As there is no clinically available instrument to systematically and reliably determine the photosensitivity thresholds of patients with dry eyes, blepharospasms, migraines, traumatic brain injuries, and genetic disorders such as Achromatopsia, retinitis pigmentosa and other retinal dysfunctions, a computer-controlled optoelectronics system was designed. The BPEI Photosensitivity System provides a light stimuli emitted from a bi-cupola concave, 210 white LED array with varying intensity ranging from 1 to 32,000 lux. The system can either utilize a normal or an enhanced testing mode for subjects with low light tolerance. The automated instrument adjusts the intensity of each light stimulus. The subject is instructed to indicate discomfort by pressing a hand-held button. Reliability of the responses is tracked during the test. The photosensitivity threshold is then calculated after 10 response reversals. In a preliminary study, we demonstrated that subjects suffering from Achromatopsia experienced lower photosensitivity thresholds than normal subjects. Hence, the system can safely and reliably determine the photosensitivity thresholds of healthy and light sensitive subjects by detecting and quantifying the individual differences. Future studies will be performed with this system to determine the photosensitivity threshold differences between normal subjects and subjects suffering from other conditions that affect light sensitivity.

  7. Fringe image processing based on structured light series

    NASA Astrophysics Data System (ADS)

    Gai, Shaoyan; Da, Feipeng; Li, Hongyan

    2009-11-01

    The code analysis of the fringe image is playing a vital role in the data acquisition of structured light systems, which affects precision, computational speed and reliability of the measurement processing. According to the self-normalizing characteristic, a fringe image processing method based on structured light is proposed. In this method, a series of projective patterns is used when detecting the fringe order of the image pixels. The structured light system geometry is presented, which consist of a white light projector and a digital camera, the former projects sinusoidal fringe patterns upon the object, and the latter acquires the fringe patterns that are deformed by the object's shape. Then the binary images with distinct white and black strips can be obtained and the ability to resist image noise is improved greatly. The proposed method can be implemented easily and applied for profile measurement based on special binary code in a wide field.

  8. Plasmonic nanofocusing of light in an integrated silicon photonics platform.

    PubMed

    Desiatov, Boris; Goykhman, Ilya; Levy, Uriel

    2011-07-04

    The capability to focus electromagnetic energy at the nanoscale plays an important role in nanoscinece and nanotechnology. It allows enhancing light matter interactions at the nanoscale with applications related to nonlinear optics, light emission and light detection. It may also be used for enhancing resolution in microscopy, lithography and optical storage systems. Hereby we propose and experimentally demonstrate the nanoscale focusing of surface plasmons by constructing an integrated plasmonic/photonic on chip nanofocusing device in silicon platform. The device was tested directly by measuring the optical intensity along it using a near-field microscope. We found an order of magnitude enhancement of the intensity at the tip's apex. The spot size is estimated to be 50 nm. The demonstrated device may be used as a building block for "lab on a chip" systems and for enhancing light matter interactions at the apex of the tip.

  9. Development of a hybrid atomic force microscopic measurement system combined with white light scanning interferometry.

    PubMed

    Guo, Tong; Wang, Siming; Dorantes-Gonzalez, Dante J; Chen, Jinping; Fu, Xing; Hu, Xiaotang

    2012-01-01

    A hybrid atomic force microscopic (AFM) measurement system combined with white light scanning interferometry for micro/nanometer dimensional measurement is developed. The system is based on a high precision large-range positioning platform with nanometer accuracy on which a white light scanning interferometric module and an AFM head are built. A compact AFM head is developed using a self-sensing tuning fork probe. The head need no external optical sensors to detect the deflection of the cantilever, which saves room on the head, and it can be directly fixed under an optical microscopic interferometric system. To enhance the system's dynamic response, the frequency modulation (FM) mode is adopted for the AFM head. The measuring data can be traceable through three laser interferometers in the system. The lateral scanning range can reach 25 mm × 25 mm by using a large-range positioning platform. A hybrid method combining AFM and white light scanning interferometry is proposed to improve the AFM measurement efficiency. In this method, the sample is measured firstly by white light scanning interferometry to get an overall coarse morphology, and then, further measured with higher resolution by AFM. Several measuring experiments on standard samples demonstrate the system's good measurement performance and feasibility of the hybrid measurement method.

  10. Multiple-channel ultra-violet absorbance detector for two-dimensional chromatographic separations.

    PubMed

    Lynch, Kyle B; Yang, Yu; Ren, Jiangtao; Liu, Shaorong

    2018-05-01

    In recent years, much research has gone into developing online comprehensive two-dimensional liquid chromatographic systems allowing for high peak capacities in comparable separation times to that of one-dimensional liquid chromatographic systems. However, the speed requirements in the second dimension (2nd-D) still remain one challenge for complex biological samples due to the current configuration of two column/two detector systems. Utilization of multiple 2nd-D columns can mitigate this challenge. To adapt this approach, we need a multiple channel detector. Here we develop a versatile multichannel ultraviolet (UV) light absorbance detector that is capable of simultaneously monitoring separations in 12 columns. The detector consists of a deuterium lighthouse, a flow cell assembly (a 13-channel flow cell fitted with a 13-photodiode-detection system), and a data acquisition and monitoring terminal. Through the use of a custom high optical quality furcated fiber to improve light transmission, precise machining of a flow cell to reduce background stray light through precision alignment, and sensitive electronic circuitry to reduce electronic noise through an active low pass filter, the background noise level is measured in the tens of µAU. We obtain a linear dynamic range of close to three orders of magnitude. Compared to a commercialized multichannel UV light absorbance detector like the Waters 2488 UV/Vis, our device provides an increase in channel detection while residing within the same noise region and linear range. Copyright © 2018 Elsevier B.V. All rights reserved.

  11. Real-time optical monitoring of microbial growth using optimal combination of light-emitting diodes

    NASA Astrophysics Data System (ADS)

    Kobayashi, Ken-ichi; Yamada, Takeshi; Hiraishi, Akira; Nakauchi, Shigeki

    2012-12-01

    We developed a real-time optical monitoring system consisting of a monochrome complementary metal-oxide semiconductor (CMOS) camera and two light-emitting diodes (LEDs) with a constant temperature incubator for the rapid detection of microbial growth on solid media. As a target organism, we used Alicyclobacillus acidocaldarius, which is an acidophilic thermophilic endospore-forming bacterium able to survive in pasteurization processes and grow in acidic drink products such as apple juice. This bacterium was cultured on agar medium with a redox dye applied to improve detection sensitivity. On the basis of spectroscopic properties of the colony, medium, and LEDs, an optimal combination of two LED illuminations was selected to maximize the contrast between the colony and medium areas. We measured A. acidocaldarius and Escherichia coli at two different dilution levels using these two LEDs. From the results of time-course changes in the number of detected pixels in the detection images, a similar growth rate was estimated amongst the same species of microbes, regardless of the dilution level. This system has the ability to detect a colony of approximately 26 μm in diameter in a detection image, and it can be interpreted that the size corresponds to less than 20 μm diameter in visual inspection.

  12. Portable multispectral fluorescence imaging system for food safety applications

    NASA Astrophysics Data System (ADS)

    Lefcourt, Alan M.; Kim, Moon S.; Chen, Yud-Ren

    2004-03-01

    Fluorescence can be a sensitive method for detecting food contaminants. Of particular interest is detection of fecal contamination as feces is the source of many pathogenic organisms. Feces generally contain chlorophyll a and related compounds due to ingestion of plant materials, and these compounds can readily be detected using fluorescence techniques. Described is a fluorescence-imaging system consisting primarily of a UV light source, an intensified camera with a six-position filter wheel, and software for controlling the system and automatically analyzing the resulting images. To validate the system, orchard apples artificially contaminated with dairy feces were used in a "hands-on" public demonstration. The contamination sites were easily identified using automated edge detection and threshold detection algorithms. In addition, by applying feces to apples and then washing sets of apples at hourly intervals, it was determined that five h was the minimum contact time that allowed identification of the contamination site after the apples were washed. There are many potential uses for this system, including studying the efficacy of apple washing systems.

  13. A new kind of universal smart home security safety monitoring system

    NASA Astrophysics Data System (ADS)

    Li, Biqing; Li, Zhao

    2018-04-01

    With the current level of social development, improved quality of life, existence and security issues of law and order has become an important issue. This graduation project adopts the form of wireless transmission, to STC89C52 microcontroller as the host control human infrared induction anti-theft monitoring system. The system mainly consists of main control circuit, power supply circuit, activities of the human body detection module, sound and light alarm circuit, record and display circuit. The main function is to achieve exploration activities on the human body, then the information is transmitted to the control panel, according to the system microcontroller program control sound and light alarm circuit, while recording the alarm location and time, and always check the record as required, and ultimately achieve the purpose of monitoring. The advantage of using pyroelectric infrared sensor can be installed in a hidden place, not easy to find, and low cost, good detection results, and has broad prospects for development.

  14. Applications of optical sensing for laser cutting and drilling.

    PubMed

    Fox, Mahlen D T; French, Paul; Peters, Chris; Hand, Duncan P; Jones, Julian D C

    2002-08-20

    Any reliable automated production system must include process control and monitoring techniques. Two laser processing techniques potentially lending themselves to automation are percussion drilling and cutting. For drilling we investigate the performance of a modification of a nonintrusive optical focus control system we previously developed for laser welding, which exploits the chromatic aberrations of the processing optics to determine focal error. We further developed this focus control system for closed-loop control of laser cutting. We show that an extension of the technique can detect deterioration in cut quality, and we describe practical trials carried out on different materials using both oxygen and nitrogen assist gas. We base our techniques on monitoring the light generated by the process, captured nonintrusively by the effector optics and processed remotely from the workpiece. We describe the relationship between the temporal and the chromatic modulation of the detected light and process quality and show how the information can be used as the basis of a process control system.

  15. Reducing a congestion with introduce the greedy algorithm on traffic light control

    NASA Astrophysics Data System (ADS)

    Catur Siswipraptini, Puji; Hendro Martono, Wisnu; Hartanti, Dian

    2018-03-01

    The density of vehicles causes congestion seen at every junction in the city of jakarta due to the static or manual traffic timing lamp system consequently the length of the queue at the junction is uncertain. The research has been aimed at designing a sensor based traffic system based on the queue length detection of the vehicle to optimize the duration of the green light. In detecting the length of the queue of vehicles using infrared sensor assistance placed in each intersection path, then apply Greedy algorithm to help accelerate the movement of green light duration for the path that requires, while to apply the traffic lights regulation program based on greedy algorithm which is then stored on microcontroller with Arduino Mega 2560 type. Where a developed system implements the greedy algorithm with the help of the infrared sensor it will extend the duration of the green light on the long vehicle queue and accelerate the duration of the green light at the intersection that has the queue not too dense. Furthermore, the design is made to form an artificial form of the actual situation of the scale model or simple simulator (next we just called as scale model of simulator) of the intersection then tested. Sensors used are infrared sensors, where the placement of sensors in each intersection on the scale model is placed within 10 cm of each sensor and serves as a queue detector. From the results of the test process on the scale model with a longer queue obtained longer green light time so it will fix the problem of long queue of vehicles. Using greedy algorithms can add long green lights for 2 seconds on tracks that have long queues at least three sensor levels and accelerate time at other intersections that have longer queue sensor levels less than level three.

  16. Fiber optic device for sensing the presence of a gas

    DOEpatents

    Benson, David K.; Bechinger, Clemens S.; Tracy, C. Edwin

    1998-01-01

    A fiber-optic device for sensing the presence of a gas in an environment is provided. The device comprises a light source for directing a light beam to a layer system having a first surface and a second surface opposite the first surface. The first surface is exposable to the light beam and the second surface is exposable to the environment. A first light portion encounters and reflects from the first surface at an angle of incidence free from optical wave guide resonance phenomenon and the second light portion encounters and reflects from the first surface at an angle of incidence enabling an optical wave guide resonance phenomenon. The layer system is selected to reversibly react with the gas to be detected. The reaction between the gas and the material changes the material's optical properties and the wavelength at which the optical wave guide resonance occurs. Furthermore, a mechanism for measuring the intensity of the reflected first light portion relative to the reflected second light portion is provided with the ratio of the first and second light portions indicating the concentration of the gas presence in the environment.

  17. Development of Speckle Interferometry Algorithm and System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shamsir, A. A. M.; Jafri, M. Z. M.; Lim, H. S.

    2011-05-25

    Electronic speckle pattern interferometry (ESPI) method is a wholefield, non destructive measurement method widely used in the industries such as detection of defects on metal bodies, detection of defects in intergrated circuits in digital electronics components and in the preservation of priceless artwork. In this research field, this method is widely used to develop algorithms and to develop a new laboratory setup for implementing the speckle pattern interferometry. In speckle interferometry, an optically rough test surface is illuminated with an expanded laser beam creating a laser speckle pattern in the space surrounding the illuminated region. The speckle pattern is opticallymore » mixed with a second coherent light field that is either another speckle pattern or a smooth light field. This produces an interferometric speckle pattern that will be detected by sensor to count the change of the speckle pattern due to force given. In this project, an experimental setup of ESPI is proposed to analyze a stainless steel plate using 632.8 nm (red) wavelength of lights.« less

  18. Transit timing analysis of the exoplanet TrES-5 b. Possible existence of the exoplanet TrES-5 c

    NASA Astrophysics Data System (ADS)

    Sokov, Eugene N.; Sokova, Iraida A.; Dyachenko, Vladimir V.; Rastegaev, Denis A.; Burdanov, Artem; Rusov, Sergey A.; Benni, Paul; Shadick, Stan; Hentunen, Veli-Pekka; Salisbury, Mark; Esseiva, Nicolas; Garlitz, Joe; Bretton, Marc; Ogmen, Yenal; Karavaev, Yuri; Ayiomamitis, Anthony; Mazurenko, Oleg; Alonso, David Molina; Velichko, Sergey F.

    2018-06-01

    In this work, we present transit timing variations detected for the exoplanet TrES-5b. To obtain the necessary amount of photometric data for this exoplanet, we have organized an international campaign to search for exoplanets based on the Transit Timing Variation method (TTV) and as a result of this we collected 30 new light curves, 15 light curves from the Exoplanet Transit Database (ETD) and 8 light curves from the literature for the timing analysis of the exoplanet TrES-5b. We have detected timing variations with a semi-amplitude of A ≈ 0.0016 days and a period of P ≈ 99 days. We carried out the N-body modeling based on the three-body problem. The detected perturbation of TrES-5b may be caused by a second exoplanet in the TrES-5 system. We have calculated the possible mass and resonance of the object: M ≈ 0.24MJup at a 1:2 Resonance.

  19. The Road to the Common PET/CT Detector

    NASA Astrophysics Data System (ADS)

    Nassalski, Antoni; Moszynski, Marek; Szczesniak, Tomasz; Wolski, Dariusz; Batsch, Tadeusz

    2007-10-01

    Growing interest in the development of dual modality positron emission/X-rays tomography (PET/CT) systems prompts researchers to face a new challenge: to acquire both the anatomical and functional information in the same measurement, simultaneously using the same detection system and electronics. The aim of this work was to study a detector consisting of LaBr3, LSO or LYSO pixel crystals coupled to an avalanche photodiode (APD). The measurements covered tests of the detectors in PET and CT modes, respectively. The measurements included the determination of light output, energy resolution, the non-proportionality of the light yield and the time resolution for 511 keV annihilation quanta; analysis also included characterizing the PET detector, and determining the dependence of counting rate versus mean current of the APD in the X-ray detection. In the present experiment, the use of counting and current modes in the CT detection increases the dynamic range of the measured dose of X-rays by a factor of 20, compared to the counting mode alone.

  20. Update on the recommended viewing protocol for FAXIL threshold contrast detail detectability test objects used in television fluoroscopy.

    PubMed

    Launders, J H; McArdle, S; Workman, A; Cowen, A R

    1995-01-01

    The significance of varying the viewing conditions that may affect the perceived threshold contrast of X-ray television fluoroscopy systems has been investigated. Factors investigated include the ambient room lighting and the viewing distance. The purpose of this study is to find the optimum viewing protocol with which to measure the threshold detection index. This is a particular problem when trying to compare the image quality of television fluoroscopy systems in different input field sizes. The results show that the viewing distance makes a significant difference to the perceived threshold contrast, whereas the ambient light conditions make no significant difference. Experienced observers were found to be capable of finding the optimum viewing distance for detecting details of each size, in effect using a flexible viewing distance. This allows the results from different field sizes to be normalized to account for both the magnification and the entrance air kerma rate differences, which in turn allow for a direct comparison of performance in different field sizes.

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