Sample records for light guide tip

  1. Effect of inhomogeneity of light from light curing units on the surface hardness of composite resin.

    PubMed

    Arikawa, Hiroyuki; Kanie, Takahito; Fujii, Koichi; Takahashi, Hideo; Ban, Seiji

    2008-01-01

    This study investigated the characteristics of output light from different types of light curing units, and their effects on polymerization of light-activated composite resin. Three quartz-tungsten-halogen lamps, one plasma arc lamp, and one LED light curing unit were used. Intensity distribution of light emitted from the light guide tip was measured at 1.0-mm intervals across the guide tip. Distribution of Knoop hardness number on the surface of resin irradiated with the light curing units was also measured. For all units, inhomogeneous distribution of light intensity across the guide tip was observed. Minimum light intensity values were 19-80% of the maximum values. In terms of surface hardness, inhomogeneous distribution was also observed for the materials irradiated with the tested units. Minimum values were 53-92% of the maximum values. Our results indicated that markedly inhomogeneous light emitted from light curing unit could result in inhomogeneous polymerization in some areas of the restoration below the light guide tip.

  2. Evaluation of degree of conversion and hardness of dental composites photo-activated with different light guide tips.

    PubMed

    Galvão, Marília Regalado; Caldas, Sergei Godeiro Fernandes Rabelo; Bagnato, Vanderlei Salvador; de Souza Rastelli, Alessandra Nara; de Andrade, Marcelo Ferrarezi

    2013-01-01

    The aim of this study was to evaluate the degree of conversion and hardness of different composite resins, photo-activated for 40 s with two different light guide tips, fiber optic and polymer. Five specimens were made for each group evaluated. The percentage of unreacted carbon double bonds (% C═C) was determined from the ratio of absorbance intensities of aliphatic C═C (peak at 1637 cm(-1)) against internal standard before and after curing of the specimen: aromatic C-C (peak at 1610 cm(-1)). The Vickers hardness measurements were performed in a universal testing machine. A 50 gf load was used and the indenter with a dwell time of 30 seconds. The degree of conversion and hardness mean values were analyzed separately by ANOVA and Tukey's test, with a significance level set at 5%. The mean values of degree of conversion for the polymer and fiber optic light guide tip were statistically different (P<.001). The hardness mean values were statistically different among the light guide tips (P<.001), but also there was difference between top and bottom surfaces (P<.001). The results showed that the resins photo-activated with the fiber optic light guide tip promoted higher values for degree of conversion and hardness.

  3. Evaluation of degree of conversion and hardness of dental composites photo-activated with different light guide tips

    PubMed Central

    Galvão, Marília Regalado; Caldas, Sergei Godeiro Fernandes Rabelo; Bagnato, Vanderlei Salvador; de Souza Rastelli, Alessandra Nara; de Andrade, Marcelo Ferrarezi

    2013-01-01

    Objective: The aim of this study was to evaluate the degree of conversion and hardness of different composite resins, photo-activated for 40 s with two different light guide tips, fiber optic and polymer. Methods: Five specimens were made for each group evaluated. The percentage of unreacted carbon double bonds (% C═C) was determined from the ratio of absorbance intensities of aliphatic C═C (peak at 1637 cm−1) against internal standard before and after curing of the specimen: aromatic C-C (peak at 1610 cm−1). The Vickers hardness measurements were performed in a universal testing machine. A 50 gf load was used and the indenter with a dwell time of 30 seconds. The degree of conversion and hardness mean values were analyzed separately by ANOVA and Tukey’s test, with a significance level set at 5%. Results: The mean values of degree of conversion for the polymer and fiber optic light guide tip were statistically different (P<.001). The hardness mean values were statistically different among the light guide tips (P<.001), but also there was difference between top and bottom surfaces (P<.001). Conclusions: The results showed that the resins photo-activated with the fiber optic light guide tip promoted higher values for degree of conversion and hardness. PMID:23407620

  4. A method for improving the light intensity distribution in dental light-curing units.

    PubMed

    Arikawa, Hiroyuki; Takahashi, Hideo; Minesaki, Yoshito; Muraguchi, Kouichi; Matsuyama, Takashi; Kanie, Takahito; Ban, Seiji

    2011-01-01

    A method for improving the uniformity of the radiation light from dental light-curing units (LCUs), and the effect on the polymerization of light-activated composite resin are investigated. Quartz-tungsten halogen, plasma-arc, and light-emitting diode LCUs were used, and additional optical elements such as a mixing tube and diffusing screen were employed to reduce the inhomogeneity of the radiation light. The distribution of the light intensity from the light guide tip was measured across the guide tip, as well as the distribution of the surface hardness of the light-activated resin emitted with the LCUs. Although the additional optical elements caused 13.2-25.9% attenuation of the light intensity, the uniformity of the light intensity of the LCUs was significantly improved in the modified LCUs, and the uniformity of the surface hardness of the resin was also improved. Our results indicate that the addition of optical elements to the LCU may be a simple and effective method for reducing inhomogeneity in radiation light from the LCUs.

  5. Eye Drop Tips

    MedlinePlus

    ... Size Small Text Medium Text Large Text Contrast Dark on Light Light on Dark Donate Search Menu Donate What is Glaucoma? Care ... Low Vision Resources Medication Guide Resources on the Web » See All Articles Where the Money Goes Have ...

  6. Design of a multifiber light delivery system for photoacoustic-guided surgery.

    PubMed

    Eddins, Blackberrie; Bell, Muyinatu A Lediju

    2017-04-01

    This work explores light delivery optimization for photoacoustic-guided minimally invasive surgeries, such as the endonasal transsphenoidal approach. Monte Carlo simulations were employed to study three-dimensional light propagation in tissue, comprising one or two 4-mm diameter arteries located 3 mm below bone, an absorbing metallic drill contacting the bone surface, and a single light source placed next to the 2.4-mm diameter drill shaft with a 2.9-mm diameter spherical drill tip. The optimal fiber distance from the drill shaft was determined from the maximum normalized fluence to the underlying artery. Using this optimal fiber-to-drill shaft distance, Zemax simulations were employed to propagate Gaussian beams through one or more 600 micron-core diameter optical fibers for detection on the bone surface. When the number of equally spaced fibers surrounding the drill increased, a single merged optical profile formed with seven or more fibers, determined by thresholding the resulting light profile images at 1 / e times the maximum intensity. We used these simulations to inform design requirements, build a one to seven multifiber light delivery prototype to surround a surgical drill, and demonstrate its ability to simultaneously visualize the tool tip and blood vessel targets in the absence and presence of bone. The results and methodology are generalizable to multiple interventional photoacoustic applications.

  7. Design of a multifiber light delivery system for photoacoustic-guided surgery

    NASA Astrophysics Data System (ADS)

    Eddins, Blackberrie; Bell, Muyinatu A. Lediju

    2017-04-01

    This work explores light delivery optimization for photoacoustic-guided minimally invasive surgeries, such as the endonasal transsphenoidal approach. Monte Carlo simulations were employed to study three-dimensional light propagation in tissue, comprising one or two 4-mm diameter arteries located 3 mm below bone, an absorbing metallic drill contacting the bone surface, and a single light source placed next to the 2.4-mm diameter drill shaft with a 2.9-mm diameter spherical drill tip. The optimal fiber distance from the drill shaft was determined from the maximum normalized fluence to the underlying artery. Using this optimal fiber-to-drill shaft distance, Zemax simulations were employed to propagate Gaussian beams through one or more 600 micron-core diameter optical fibers for detection on the bone surface. When the number of equally spaced fibers surrounding the drill increased, a single merged optical profile formed with seven or more fibers, determined by thresholding the resulting light profile images at 1/e times the maximum intensity. We used these simulations to inform design requirements, build a one to seven multifiber light delivery prototype to surround a surgical drill, and demonstrate its ability to simultaneously visualize the tool tip and blood vessel targets in the absence and presence of bone. The results and methodology are generalizable to multiple interventional photoacoustic applications.

  8. Tips for Managing Your Classroom. Adapted from Chapter 4 of "What To Do With the Kid Who.... Developing Cooperation, Self-Discipline, and Responsibility in the Classroom, 2nd Edition." A SkyLight Guide.

    ERIC Educational Resources Information Center

    Burke, Kay

    This booklet provides proactive guidelines to help teachers manage the classroom environment. The tips explain how to establish procedures and create rules for behavior that will enable teachers to clarify their expectations for the students and reduce the number of classroom incidents that interfere with instruction. The guidelines are intended…

  9. Use of a fiberscope for examining cavity nests

    Treesearch

    Kathryn L. Purcell

    1997-01-01

    A system is described that uses a fiberscope to view nests in cavities to provide detailed information on eggs and nestlings. The flexible probe can be inserted around bends, and the tip articulates to allow viewing of the entire cavity and nest. A light guide bundle furnishes light to enable viewing of dark cavities and optical fibers transmit the impage from the lens...

  10. A novel drill design for photoacoustic guided surgeries

    NASA Astrophysics Data System (ADS)

    Shubert, Joshua; Lediju Bell, Muyinatu A.

    2018-02-01

    Fluoroscopy is currently the standard approach for image guidance of surgical drilling procedures. In addition to the harmful radiation dose to the patient and surgeon, fluoroscopy fails to visualize critical structures such as blood vessels and nerves within the drill path. Photoacoustic imaging is a well-suited imaging method to visualize these structures and it does not require harmful ionizing radiation. However, there is currently no clinical system available to deliver light to occluded drill bit tips. To address this challenge, a prototype drill was designed, built, and tested using an internal light delivery system that allows laser energy to be transferred from a stationary laser source to the tip of a spinning drill bit. Photoacoustic images were successfully obtained with the drill bit submerged in water and with the drill tip inserted into a thoracic vertebra from a human cadaver.

  11. Distance and protective barrier effects on the composite resin degree of conversion

    PubMed Central

    Coutinho, Margareth; Trevizam, Natália Carvalho; Takayassu, Renata Nakase; Leme, Ariene Arcas; Soares, Giulliana Panfiglio

    2013-01-01

    Context: The food wrap films are used to cover the tip of curing light units in order to avoid contamination and prevent damage to the light guide. However, their effects on resin polymerization are not fully known. Aims: We investigated the effects on restoration efficiency of a food wrap protective barrier used on the tip of curing light units. Materials and Methods: For each treatment, five replications were performed, a total of 60 bovine incisor. The degree of conversion (%DC) of restorations with the composite resin Opallis EA2 was evaluated using 3 curing light devices (Optilux 501, Optilight and Ultra LED) and 2 curing distances (0 and 5 mm). The composite resin was tested for restoration of cavities in bovine crowns. %DC values were measured by the Fourier transform infrared spectroscopy-attenuated total reflectance technique. Statistical Analysis Used: The data were analyzed using 3-way ANOVA and Tukey's test. Results: Use of the protective film lowered %DC (F = 4.13; P = 0.05), and the effects of curing distance were associated to the curing light device (F = 3.61; P = 0.03). Conclusions: The distance from the light curing tip and use of a translucent protective barrier on the light-cure device can both impair composite resin %DC. PMID:24015001

  12. Optical fiber-based fluorescent viscosity sensor

    NASA Astrophysics Data System (ADS)

    Haidekker, Mark A.; Akers, Walter J.; Fischer, Derek; Theodorakis, Emmanuel A.

    2006-09-01

    Molecular rotors are a unique group of viscosity-sensitive fluorescent probes. Several recent studies have shown their applicability as nonmechanical fluid viscosity sensors, particularly in biofluids containing proteins. To date, molecular rotors have had to be dissolved in the fluid for the measurement to be taken. We now show that molecular rotors may be covalently bound to a fiber-optic tip without loss of viscosity sensitivity. The optical fiber itself may be used as a light guide for emission light (external illumination of the tip) as well as for both emission and excitation light. Covalently bound molecular rotors exhibit a viscosity-dependent intensity increase similar to molecular rotors in solution. An optical fiber-based fluorescent viscosity sensor may be used in real-time measurement applications ranging from biomedical applications to the food industry.

  13. Optical fiber-based fluorescent viscosity sensor.

    PubMed

    Haidekker, Mark A; Akers, Walter J; Fischer, Derek; Theodorakis, Emmanuel A

    2006-09-01

    Molecular rotors are a unique group of viscosity-sensitive fluorescent probes. Several recent studies have shown their applicability as nonmechanical fluid viscosity sensors, particularly in biofluids containing proteins. To date, molecular rotors have had to be dissolved in the fluid for the measurement to be taken. We now show that molecular rotors may be covalently bound to a fiber-optic tip without loss of viscosity sensitivity. The optical fiber itself may be used as a light guide for emission light (external illumination of the tip) as well as for both emission and excitation light. Covalently bound molecular rotors exhibit a viscosity-dependent intensity increase similar to molecular rotors in solution. An optical fiber-based fluorescent viscosity sensor may be used in real-time measurement applications ranging from biomedical applications to the food industry.

  14. Fiber sensor assisted in-vivo needle guidance for minimally invasive procedures (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Baghdadchi, Saharnaz; Chao, Cherng; Esener, Sadik; Mattrey, Robert F.; Eghtedari, Mohammad A.

    2017-02-01

    Image-guided procedures are performed frequently by radiologists to insert a catheter within a target vessel or lumen or to perform biopsy of a lesion. For instance, an interventional radiologist uses fluoroscopy during percutaneous biliary drainage procedure (a procedure during which a catheter is inserted through the skin to drain the bile from liver) to identify the location of the needle tip within liver parenchyma, hepatic blood vessel or bile duct. However, the identification of the target organ under fluoroscopy exposes the patient to x-ray irradiation, which may be significant if the time of procedure is prolonged. We have designed a fiber core needle system that may help the radiologist identify the location of the needle tip in real time without exposing the patient to x-ray. Our needle system transmits a low power modulated light into the tissue through a fiber cable embedded in the needle and detects the backscattered light using another fiber inside the needle. We were able to successfully distinguish the location of our prototype needle tip inside a cow liver phantom to identify if the needle tip was within liver parenchyma, liver vessels, or in the bile duct based on the recorded backscattered light.

  15. A near-infrared tip-tilt sensor for the Keck I laser guide star adaptive optics system

    NASA Astrophysics Data System (ADS)

    Wizinowich, Peter; Smith, Roger; Biasi, Roberto; Cetre, Sylvain; Dekany, Richard; Femenia-Castella, Bruno; Fucik, Jason; Hale, David; Neyman, Chris; Pescoller, Dietrich; Ragland, Sam; Stomski, Paul; Andrighettoni, Mario; Bartos, Randy; Bui, Khanh; Cooper, Andrew; Cromer, John; van Dam, Marcos; Hess, Michael; James, Ean; Lyke, Jim; Rodriguez, Hector; Stalcup, Thomas

    2014-07-01

    The sky coverage and performance of laser guide star (LGS) adaptive optics (AO) systems is limited by the natural guide star (NGS) used for low order correction. This limitation can be dramatically reduced by measuring the tip and tilt of the NGS in the near-infrared where the NGS is partially corrected by the LGS AO system and where stars are generally several magnitudes brighter than at visible wavelengths. We present the design of a near-infrared tip-tilt sensor that has recently been integrated with the Keck I telescope's LGS AO system along with some initial on-sky results. The implementation involved modifications to the AO bench, real-time control system, and higher level controls and operations software that will also be discussed. The tip-tilt sensor is a H2RG-based near-infrared camera with 0.05 arc second pixels. Low noise at high sample rates is achieved by only reading a small region of interest, from 2×2 to 16×16 pixels, centered on an NGS anywhere in the 100 arc second diameter field. The sensor operates at either Ks or H-band using light reflected by a choice of dichroic beamsplitters located in front of the OSIRIS integral field spectrograph.

  16. The effect of infection-control barriers on the light intensity of light-cure units and depth of cure of composite.

    PubMed

    Hodson, Nicholas A; Dunne, Stephen M; Pankhurst, Caroline L

    2005-04-01

    Dental curing lights are vulnerable to contamination with oral fluids during routine intra-oral use. This controlled study aimed to evaluate whether or not disposable transparent barriers placed over the light-guide tip would affect light output intensity or the subsequent depth of cure of a composite restoration. The impact on light intensity emitted from high-, medium- and low-output light-cure units in the presence of two commercially available disposable infection-control barriers was evaluated against a no-barrier control. Power density measurements from the three intensity light-cure units were recorded with a radiometer, then converted to a digital image using an intra-oral camera and values determined using a commercial computer program. For each curing unit, the measurements were repeated on ten separate occasions with each barrier and the control. Depth of cure was evaluated using a scrape test in a natural tooth model. At each level of light output, the two disposable barriers produced a significant reduction in the mean power density readings compared to the no-barrier control (P<0.005). The cure sleeve inhibited light output to a greater extent than either the cling film or the control (P<0.005). Only composite restorations light-activated by the high level unit demonstrated a small but significant decrease in the depth of cure compared to the control (P<0.05). Placing disposable barriers over the light-guide tip reduced the light intensity from all three curing lights. There was no impact on depth of cure except for the high-output light, where a small decrease in cure depth was noted but this was not considered clinically significant. Disposable barriers can be recommended for use with light-cure lights.

  17. Turbine-blade tip clearance and tip timing measurements using an optical fiber bundle sensor

    NASA Astrophysics Data System (ADS)

    Garcia, Iker; Beloki, Josu; Zubia, Joseba; Durana, Gaizka; Aldabaldetreku, Gotzon

    2013-04-01

    Traditional limitations of capacitive, inductive or discharging probe sensor for tip timing and tip clearance measurements are overcome by reflective intensity modulated optical fiber sensors. This paper presents the signals and results corresponding to a one stage turbine rig which rotor has 146 blades, obtained from a transonic wind-tunnel test. The probe is based on a trifurcated bundle of optical fibers that is mounted on turbine casing. It is composed of a central illuminating fiber that guides the light from a laser to the turbine blade, and two concentric rings of receiving fibers that collect the reflected light. Two photodetectors turn this reflected light signal from the receiving rings into voltage. The electrical signals are acquired and saved by a high-sample-rate oscilloscope. In tip clearance calculations the ratio of the signals provided by each ring of receiving fibers is evaluated and translated into distance. In the case of tip timing measurements, only one of the signals is considered to get the arrival time of the blade. The differences between the real and theoretical arrival times of the blades are used to obtain the deflections amplitude. The system provides the travelling wave spectrum, which presents the average vibration amplitude of the blades at a certain nodal diameter. The reliability of the results in the turbine rig testing facilities suggests the possibility of performing these measurements in real turbines under real working conditions.

  18. A Guide to Energy Savings - For the Dairy Farmers.

    ERIC Educational Resources Information Center

    Frank, Gary G.

    This booklet gives a brief overview of energy use patterns in a dairy farm and gives tips on cutting costs of water heating, ventilation and supplemental heat, milk cooling, vacuum pumps, electric motors, tractors, trucks, engines, and lighting. Finally, energy use recordkeeping is discussed. (BB)

  19. An optoacoustic guide with augmented reality system towards precision breast conserving surgery (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Lan, Lu; Liu, Kaiming; Xia, Yan; Wu, Jiayingzi; Li, Rui; Wang, Pu; Han, Linda K.; Cheng, Ji-Xin

    2017-02-01

    Breast-conserving surgery is a well-accepted breast cancer treatment. However, it is still challenging for the surgeon to accurately localize the tumor during the surgery. Also, the guidance provided by current methods is 1 dimensional distance information, which is indirect and not intuitive. Therefore, it creates problems on a large re-excision rate, and a prolonged surgical time. To solve these problems, we have developed a fiber-delivered optoacoustic guide (OG), which mimics the traditional localization guide wire and is preoperatively placed into tumor mass, and an augmented reality (AR) system to provide real-time visualization on the location of the tumor with sub-millimeter variance. By a nano-composite light diffusion sphere and light absorbing layer formed on the tip of an optical fiber, the OG creates an omnidirectional acoustic source inside tumor mass under pulsed laser excitation. The optoacoustic signal generated has a high dynamic range ( 58dB) and spreads in a large apex angle of 320 degrees. Then, an acoustic radar with three ultrasound transducers is attached to the breast skin, and triangulates the location of the OG tip. With an AR system to sense the location of the acoustic radar, the relative position of the OG tip inside the tumor to the AR display is calculated and rendered. This provides direct visual feedback of the tumor location to surgeons, which will greatly ease the surgical planning during the operation and save surgical time. A proof-of-concept experiment using a tablet and a stereo-vision camera is demonstrated and 0.25 mm tracking variance is achieved.

  20. Anatomy-driven design of a prototype video laryngoscope for extremely low birth weight infants

    NASA Astrophysics Data System (ADS)

    Baker, Katherine; Tremblay, Eric; Karp, Jason; Ford, Joseph; Finer, Neil; Rich, Wade

    2010-11-01

    Extremely low birth weight (ELBW) infants frequently require endotracheal intubation for assisted ventilation or as a route for administration of drugs or exogenous surfactant. In adults and less premature infants, the risks of this intubation can be greatly reduced using video laryngoscopy, but current products are too large and incorrectly shaped to visualize an ELBW infant's airway anatomy. We design and prototype a video laryngoscope using a miniature camera set in a curved acrylic blade with a 3×6-mm cross section at the tip. The blade provides a mechanical structure for stabilizing the tongue and acts as a light guide for an LED light source, located remotely to avoid excessive local heating at the tip. The prototype is tested on an infant manikin and found to provide sufficient image quality and mechanical properties to facilitate intubation. Finally, we show a design for a neonate laryngoscope incorporating a wafer-level microcamera that further reduces the tip cross section and offers the potential for low cost manufacture.

  1. A PREP Panel, Practice-Based, Evaluation of the Handling of the Kerr Demi-Ultra Light Curing Unit.

    PubMed

    Burke, F J Trevor; Crisp, Russell J

    2015-09-01

    This paper describes the handling evaluation (by a group of practice-based researchers, the PREP Panel) of a recently introduced Light Curing Unit (LCU), the Kerr Demi-Ultra, which possesses a number of novel features such as its ultracapacitor power source, and the Light Emitting Diodes (LEDs) which provide the light output being placed close to the tip of the light guide. CPD/CLINICAL RELEVANCE: Testing of new devices and materials with respect to their handling is of importance, given that an easy to handle device should produce better clinical results than one which is difficult to use.

  2. Effect of cross infection control barriers used on the light-curing device tips on the cure depth of a resin composite

    PubMed Central

    de Moraes Porto, Isabel Cristina Celerino; Ramos de Brito, Andréia Cristina; Parolia, Abhishek

    2013-01-01

    Background: Among the advice on prevent cross-infection was included usage of mechanical barriers on tips of photoactivation units. However, questions about the use of protective barriers placed on the light-curing unit's tips and the possibility of interference with the ability of guaranteeing an effective polymerization of composite resins need to be clarified. Aims: The aim of this study was to evaluate the effect of cross infection control barriers used on the light-curing device tips on the cure depth of composite resin. Materials and Methods: Power density measurements from the light-cure unit were recorded with a radiometer on ten separate occasions with different types and placement modes of each barrier (low-density polyethylene and polyvinyl chloride (PVC) film – smooth and folds) and no-barrier (control). Cure depth of TPH™ Spectrum™ resin, A2-A4, was evaluated by the scraping test. Statistical Analysis: The data were analyzed using Student's t-test or ANOVA one-way with Tukey's test (α =0.05). Results: Same type of barrier and different shades (A2, A4) of composite exhibited significant difference in the cure depth among all groups (P < 0.05). Both low-density polyethylene and PVC film folded barriers produced a significant reduction in the light intensity (P < 0.05). Conclusions: Regarding the resin shade, there was a significant reduction in the cure depth of A4 composite resin (dark shade) but this reduction is not enough to cause any adverse effect on the material's clinical performance. Therefore, disposable barriers can be recommended for use over the end of the light guide. PMID:23833455

  3. Realtime system for GLAS on WHT

    NASA Astrophysics Data System (ADS)

    Skvarč, Jure; Tulloch, Simon; Myers, Richard M.

    2006-06-01

    The new ground layer adaptive optics system (GLAS) on the William Herschel Telescope (WHT) on La Palma will be based on the existing natural guide star adaptive optics system called NAOMI. A part of the new developments is a new control system for the tip-tilt mirror. Instead of the existing system, built around a custom built multiprocessor computer made of C40 DSPs, this system uses an ordinary PC machine and a Linux operating system. It is equipped with a high sensitivity L3 CCD camera with effective readout noise of nearly zero. The software design for the tip-tilt system is being completely redeveloped, in order to make a use of object oriented design which should facilitate easier integration with the rest of the observing system at the WHT. The modular design of the system allows incorporation of different centroiding and loop control methods. To test the system off-sky, we have built a laboratory bench using an artificial light source and a tip-tilt mirror. We present results of tip-tilt correction quality using different centroiding algorithms and different control loop methods at different light levels. This system will serve as a testing ground for a transition to a completely PC-based real-time control system.

  4. Utility of Intravascular US-Guided Portal Vein Access during Transjugular Intrahepatic Portosystemic Shunt Creation: Retrospective Comparison with Conventional Technique in 109 Patients.

    PubMed

    Pillai, Anil K; Andring, Brice; Faulconer, Nicholas; Reis, Stephen P; Xi, Yin; Iyamu, Ikponmwosa; Suthpin, Patrick D; Kalva, Sanjeeva P

    2016-08-01

    To compare safety and effectiveness of intravascular ultrasound (US)-guided portal vein access during transjugular intrahepatic portosystemic shunt (TIPS) creation with conventional TIPS technique. In this retrospective study, TIPS creation using intravascular US guidance in 55 patients was compared with conventional TIPS creation in 54 patients by 10 operators over a 3-year period. Operators were classified as experienced if they had performed ≥ 20 TIPS procedures at the beginning of the study period. Time to portal vein access, total radiation dose, and needle pass-related capsular perforation were recorded. Baseline demographic characteristics of patients were similar (P > .05). Mean time to portal venous access was 46 minutes ± 37 for conventional TIPS and 31 minutes ± 19 for intravascular US-guided TIPS (P = .007). Intravascular US guidance allowed significantly shorter times (48 min ± 30 vs 28 min ± 16; P = .01) to portal vein access among operators (n = 5) with limited experience but failed to achieve any significant time savings (44 min ± 43 vs 34 min ± 22; P = .89) among experienced operators (n = 5). Needle pass-related capsular perforation occurred in 17/54 (34%) patients with conventional TIPS and 5/55 (9%) patients with intravascular US-guided TIPS (P = .004). Radiation dose was 2,376 mGy ± 1,816 for conventional TIPS and 1,592 mGy ± 1,263 for intravascular US-guided TIPS (P = .004). Intravascular US-guided portal vein access during TIPS creation is associated with shorter portal vein access times, decreased needle pass-related capsular perforations, and reduced radiation dose. Copyright © 2016 SIR. Published by Elsevier Inc. All rights reserved.

  5. Visible light-sensitive APTES-bound ZnO nanowire toward a potent nanoinjector sensing biomolecules in a living cell

    NASA Astrophysics Data System (ADS)

    Lee, Jooran; Choi, Sunyoung; Bae, Seon Joo; Yoon, Seok Min; Choi, Joon Sig; Yoon, Minjoong

    2013-10-01

    Nanoscale cell injection techniques combined with nanoscopic photoluminescence (PL) spectroscopy have been important issues in high-resolution optical biosensing, gene and drug delivery and single-cell endoscopy for medical diagnostics and therapeutics. However, the current nanoinjectors remain limited for optical biosensing and communication at the subwavelength level, requiring an optical probe such as semiconductor quantum dots, separately. Here, we show that waveguided red emission is observed at the tip of a single visible light-sensitive APTES-modified ZnO nanowire (APTES-ZnO NW) and it exhibits great enhancement upon interaction with a complementary sequence-based double stranded (ds) DNA, whereas it is not significantly affected by non-complementary ds DNA. Further, the tip of a single APTES-ZnO NW can be inserted into the subcellular region of living HEK 293 cells without significant toxicity, and it can also detect the enhancement of the tip emission from subcellular regions with high spatial resolution. These results indicate that the single APTES-ZnO NW would be useful as a potent nanoinjector which can guide visible light into intracellular compartments of mammalian cells, and can also detect nanoscopic optical signal changes induced by interaction with the subcellular specific target biomolecules without separate optical probes.Nanoscale cell injection techniques combined with nanoscopic photoluminescence (PL) spectroscopy have been important issues in high-resolution optical biosensing, gene and drug delivery and single-cell endoscopy for medical diagnostics and therapeutics. However, the current nanoinjectors remain limited for optical biosensing and communication at the subwavelength level, requiring an optical probe such as semiconductor quantum dots, separately. Here, we show that waveguided red emission is observed at the tip of a single visible light-sensitive APTES-modified ZnO nanowire (APTES-ZnO NW) and it exhibits great enhancement upon interaction with a complementary sequence-based double stranded (ds) DNA, whereas it is not significantly affected by non-complementary ds DNA. Further, the tip of a single APTES-ZnO NW can be inserted into the subcellular region of living HEK 293 cells without significant toxicity, and it can also detect the enhancement of the tip emission from subcellular regions with high spatial resolution. These results indicate that the single APTES-ZnO NW would be useful as a potent nanoinjector which can guide visible light into intracellular compartments of mammalian cells, and can also detect nanoscopic optical signal changes induced by interaction with the subcellular specific target biomolecules without separate optical probes. Electronic supplementary information (ESI) available: Synthesis of APTES-modified ZnO nanowires, DNA functionalization and spectroscopic measurements with additional fluorescence image ad fluorescence decay times, cell culture, injection of a single nanowire into living cells, subcellular imaging and determination of cytotoxicity. See DOI: 10.1039/c3nr03042c

  6. Teaching Elementary School Students to Be Effective Writers: Instructional Tips Based on the Educator's Practice Guide

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2017

    2017-01-01

    Instructional tips help educators carry out recommendations contained in IES Educator's Practice Guides. The tips, based on a practice guide authored by Steve Graham, Alisha Bollinger, Carol Booth Olson, Catherine D'Aoust, Charles MacArthur, Deborah McCutchen, and Natalie Olinghouse, translate these recommendations into actionable approaches that…

  7. Quick Tips Guide for Small Manufacturing Businesses

    EPA Pesticide Factsheets

    Small manufacturing businesses can use this Quick Tips Guide to be better prepared for future extreme weather events. This guide discusses keeping good records, improving housekeeping procedures, and training employees.

  8. Nanowire-based single-cell endoscopy

    NASA Astrophysics Data System (ADS)

    Yan, Ruoxue; Park, Ji-Ho; Choi, Yeonho; Heo, Chul-Joon; Yang, Seung-Man; Lee, Luke P.; Yang, Peidong

    2012-03-01

    One-dimensional smart probes based on nanowires and nanotubes that can safely penetrate the plasma membrane and enter biological cells are potentially useful in high-resolution and high-throughput gene and drug delivery, biosensing and single-cell electrophysiology. However, using such probes for optical communication across the cellular membrane at the subwavelength level remains limited. Here, we show that a nanowire waveguide attached to the tapered tip of an optical fibre can guide visible light into intracellular compartments of a living mammalian cell, and can also detect optical signals from subcellular regions with high spatial resolution. Furthermore, we show that through light-activated mechanisms the endoscope can deliver payloads into cells with spatial and temporal specificity. Moreover, insertion of the endoscope into cells and illumination of the guided laser did not induce any significant toxicity in the cells.

  9. Comparison of different focusing fiber tips for improved oral diode laser surgery.

    PubMed

    Stock, Karl; Stegmayer, Thomas; Graser, Rainer; Förster, Wolfram; Hibst, Raimund

    2012-12-01

    State of the art for use of the fiber guided diode laser in dental therapy is the application of bare fibers. A novel concept with delivery fiber and exchangeable fiber tips enables the use of tips with special and optimized geometries for various applications. The aim of this study is the comparison of different focusing fiber tips for enhanced cutting efficacy in oral surgery. For this purpose various designs of tip geometry were investigated and optimized by ray tracing simulations. Two applicators, one with a sphere, and another one with a taper, were realized and tested on porcine gingiva (diode laser, 940 nm, 5 W/cw; 7 W/modulated). The cutting depth and quality were determined by light microscope. Histological sections of the cuts were prepared by a cryo-microtome and microscopically analyzed to determine the cut depths and thermal damage zones. The simulations show that, using a sphere as fiber tip, an intensity increase of up to a factor of 16.2 in air, and 13.2 in water compared to a bare 200 µm fiber can be achieved. Although offering high focusing factor in water, the cutting quality of the sphere was rather poor. This is probably caused by a derogation of the focusing quality due to contamination during cutting and light scattering. Much better results were achieved with conically shaped fiber tips. Compared to bare fibers they exhibit improved handling properties with no hooking, more regular and deeper cuts (5 W/cw: 2,393 ± 468 µm, compared to the cleaved bare fiber 5 W/cw: 711 ± 268 µm). The thermal damage zones of the cuts are comparable for the various tips and fibers. In conclusion the results of our study show that cutting quality and efficiency of diode laser on soft tissue can be significantly improved using conically shaped fiber tips. Copyright © 2012 Wiley Periodicals, Inc.

  10. Teaching Elementary School Students to Be Effective Writers. Summary of Evidence for Instructional Tips Based on the Educator's Practice Guide

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2017

    2017-01-01

    Instructional tips help educators carry out recommendations contained in IES Educator's Practice Guides. This summary of evidence describes the research evidence that supports the use of the instructional tips in classrooms, and is based on a practice guide authored by Steve Graham, Alisha Bollinger, Carol Booth Olson, Catherine D'Aoust, Charles…

  11. An intraocular micro light-emitting diode device for endo-illumination during pars plana vitrectomy.

    PubMed

    Koelbl, Philipp S; Lingenfelder, Christian; Spraul, Christoph W; Kampmeier, Juergen; Koch, Frank Hj; Kim, Yong Keun; Hessling, Martin

    2018-03-01

    Development of a new, fiber-free, single-use endo-illuminator for pars plana vitrectomy as a replacement for fiber-based systems with external light sources. The hand-guided intraocularly placed white micro light-emitting diode is evaluated for its illumination properties and potential photochemical and thermal hazards. A micro light-emitting diode was used to develop a single-use intraocular illumination system. The light-source-on-tip device was implemented in a prototype with 23G trocar compatible outer diameter of 0.6 mm. The experimental testing was performed on porcine eyes. All calculations of possible photochemical and thermal hazards during the application of the intraocular micro light-emitting diode were calculated according to DIN EN ISO 15007-2: 2014. The endo-illuminator generated a homogeneous and bright illumination of the intraocular space. The color impression was physiologic and natural. Contrary to initial apprehension, the possible risk caused by inserting a light-emitting diode into the intraocular vitreous was much smaller when compared to conventional fiber-based illumination systems. The photochemical and thermal hazards allowed a continuous exposure time to the retina of at least 4.7 h. This first intraocular light source showed that a light-emitting diode can be introduced into the eye. The system can be built as single-use illumination system. This light-source-on-tip light-emitting diode-endo-illumination combines a chandelier wide-angle illumination with an adjustable endo-illuminator.

  12. Novel splice techniques and micro-hole collapse effect in photonic crystal fibers

    NASA Astrophysics Data System (ADS)

    Xiao, Limin

    Photonic crystal fibers (PCFs) represent one of the most active research areas today in the field of fiber optics. Because of the freedom they offer in their design and novel wave-guiding properties, PCFs have resulted in a number of applications that are difficult to achieve with conventional fibers. In practical applications, low-loss connection PCFs with conventional fibers is a key issue for integrating PCF devices into existing fiber optic systems. However, connecting PCFs to conventional fibers without incurring too much loss is a very challenging problem. Two novel techniques were proposed to solve this problem in the thesis. One is fusion splicing technique; the other is micro-tip technique. First, fusion splicing technique for PCFs is investigated. For fusion splicing SMFs and PCFs having similar mode field diameters, a low-loss joint with good mechanical strength can be formed by choosing a suitably weak fusion current, short fusion time, offset and overlap to minimize the collapse of air holes and well melt two fibers together. For small-core PCFs, an optimum mode field match and an adiabatic mode field variation can be achieved by repeated arc discharges. Low-loss fusion splicing of five different PCFs with SMFs are achieved, including large mode PCF, hollow-core PCF, nonlinear PCFs with low and high air-filling fraction and polarization maintaining PCF. The other novel technique is using micro-tips. The method is based on growing photopolymer micro-tips directly on the end face of SMFs. The shape and the size of the tips can be controlled, by adjusting the laser power, the exposure time and the oxygen diffusion concentration for polymerization, to match its mode field to the small-core PCFs. Micro-hole collapse effect can be used to fabricate selective injection PCFs. The suitable arc discharge energy can cause the cladding holes to collapse while leaving the central hollow core to remain open. Thus a simple method for selective filling the central hole of PCFs is developed. Hybrid PCF guides light by a novel guiding mechanism, which is a combination of index-guiding and bandgap-guiding. The properties of the hybrid PCF are systematically investigated.

  13. Pressurized air injection in an axial hydro-turbine model for the mitigation of tip leakage cavitation

    NASA Astrophysics Data System (ADS)

    Rivetti, A.; Angulo, M.; Lucino, C.; Liscia, S.

    2015-12-01

    Tip leakage vortex cavitation in axial hydro-turbines may cause erosion, noise and vibration. Damage due to cavitation can be found at the tip of the runner blades on the low pressure side and the discharge ring. In some cases, the erosion follows an oscillatory pattern that is related to the number of guide vanes. That might suggest that a relationship exists between the flow through the guide vanes and the tip vortex cavitating core that induces this kind of erosion. On the other hand, it is known that air injection has a beneficial effect on reducing the damage by cavitation. In this paper, a methodology to identify the interaction between guide vanes and tip vortex cavitation is presented and the effect of air injection in reducing this particular kind of erosion was studied over a range of operating conditions on a Kaplan scale model. It was found that air injection, at the expense of slightly reducing the efficiency of the turbine, mitigates the erosive potential of tip leakage cavitation, attenuates the interaction between the flow through the guide vanes and the tip vortex and decreases the level of vibration of the structural components.

  14. Tip vortex computer code SRATIP. User's guide

    NASA Technical Reports Server (NTRS)

    Levy, R.; Lin, S. J.

    1985-01-01

    This User's Guide applies to the three dimensional viscous flow forward marching analysis, PEPSIG, as used for the calculation of the helicopter tip vortex flow field. The guide presents a discussion of the program flow and subroutines, as well as a list of sample input and output.

  15. Tapered optical fiber tip probes based on focused ion beam-milled Fabry-Perot microcavities

    NASA Astrophysics Data System (ADS)

    André, Ricardo M.; Warren-Smith, Stephen C.; Becker, Martin; Dellith, Jan; Rothhardt, Manfred; Zibaii, M. I.; Latifi, H.; Marques, Manuel B.; Bartelt, Hartmut; Frazão, Orlando

    2016-09-01

    Focused ion beam technology is combined with dynamic chemical etching to create microcavities in tapered optical fiber tips, resulting in fiber probes for temperature and refractive index sensing. Dynamic chemical etching uses hydrofluoric acid and a syringe pump to etch standard optical fibers into cone structures called tapered fiber tips where the length, shape, and cone angle can be precisely controlled. On these tips, focused ion beam is used to mill several different types of Fabry-Perot microcavities. Two main cavity types are initially compared and then combined to form a third, complex cavity structure. In the first case, a gap is milled on the tapered fiber tip which allows the external medium to penetrate the light guiding region and thus presents sensitivity to external refractive index changes. In the second, two slots that function as mirrors are milled on the tip creating a silica cavity that is only sensitive to temperature changes. Finally, both cavities are combined on a single tapered fiber tip, resulting in a multi-cavity structure capable of discriminating between temperature and refractive index variations. This dual characterization is performed with the aid of a fast Fourier transform method to separate the contributions of each cavity and thus of temperature and refractive index. Ultimately, a tapered optical fiber tip probe with sub-standard dimensions containing a multi-cavity structure is projected, fabricated, characterized and applied as a sensing element for simultaneous temperature and refractive index discrimination.

  16. Methods for multiple-telescope beam imaging and guiding in the near-infrared

    NASA Astrophysics Data System (ADS)

    Anugu, N.; Amorim, A.; Gordo, P.; Eisenhauer, F.; Pfuhl, O.; Haug, M.; Wieprecht, E.; Wiezorrek, E.; Lima, J.; Perrin, G.; Brandner, W.; Straubmeier, C.; Le Bouquin, J.-B.; Garcia, P. J. V.

    2018-05-01

    Atmospheric turbulence and precise measurement of the astrometric baseline vector between any two telescopes are two major challenges in implementing phase-referenced interferometric astrometry and imaging. They limit the performance of a fibre-fed interferometer by degrading the instrument sensitivity and the precision of astrometric measurements and by introducing image reconstruction errors due to inaccurate phases. A multiple-beam acquisition and guiding camera was built to meet these challenges for a recently commissioned four-beam combiner instrument, GRAVITY, at the European Southern Observatory Very Large Telescope Interferometer. For each telescope beam, it measures (a) field tip-tilts by imaging stars in the sky, (b) telescope pupil shifts by imaging pupil reference laser beacons installed on each telescope using a 2 × 2 lenslet and (c) higher-order aberrations using a 9 × 9 Shack-Hartmann. The telescope pupils are imaged to provide visual monitoring while observing. These measurements enable active field and pupil guiding by actuating a train of tip-tilt mirrors placed in the pupil and field planes, respectively. The Shack-Hartmann measured quasi-static aberrations are used to focus the auxiliary telescopes and allow the possibility of correcting the non-common path errors between the adaptive optics systems of the unit telescopes and GRAVITY. The guiding stabilizes the light injection into single-mode fibres, increasing sensitivity and reducing the astrometric and image reconstruction errors. The beam guiding enables us to achieve an astrometric error of less than 50 μas. Here, we report on the data reduction methods and laboratory tests of the multiple-beam acquisition and guiding camera and its performance on-sky.

  17. Method and apparatus for guiding ablative therapy of abnormal biological electrical excitation

    NASA Technical Reports Server (NTRS)

    Armoundas, Antonis A. (Inventor); Feldman, Andrew B. (Inventor); Sherman, Derin A. (Inventor); Cohen, Richard J. (Inventor)

    2001-01-01

    This invention involves method and apparatus for guiding ablative therapy of abnormal biological electrical excitation. In particular, it is designed for treatment of cardiac arrhythmias. In the method of this invention electrical signals are acquired from passive electrodes, and an inverse dipole method is used to identify the site of origin of an arrhytmia. The location of the tip of the ablation catheter is similarly localized from signals acquired from the passive electrodes while electrical energy is delivered to the tip of the catheter. The catheter tip is then guided to the site of origin of the arrhythmia, and ablative radio frequency energy is delivered to its tip to ablate the site.

  18. Helping Your Students with Homework: A Guide for Teachers.

    ERIC Educational Resources Information Center

    Paulu, Nancy; Darby, Linda B., Ed.

    This guide for elementary and secondary teachers discusses 18 tips for creating meaningful homework assignments that students will complete. Following introductory sections that explore hurdles to homework, the guide details the following tips: (1) lay out expectations early in the school year; (2) create assignments with a purpose; (3) make sure…

  19. Tapered fiber optic applicator for laser ablation: Theoretical and experimental assessment of thermal effects on ex vivo model.

    PubMed

    Saccomandi, P; Di Matteo, F M; Schena, E; Quero, G; Massaroni, C; Giurazza, F; Costamagna, G; Silvestri, S

    2017-07-01

    Laser Ablation (LA) is a minimally invasive technique for tumor removal. The laser light is guided into the target tissue by a fiber optic applicator; thus the physical features of the applicator tip strongly influence size and shape of the tissue lesion. This study aims to verify the geometry of the lesion achieved by a tapered-tip applicator, and to investigate the percentage of thermally damaged cells induced by the tapered-tip fiber optic applicator. A theoretical model was implemented to simulate: i) the distribution of laser light fluence rate in the tissue through Monte Carlo method, ii) the induced temperature distribution, by means of the Bio Heat Equation, iii) the tissue injury, by Arrhenius integral. The results obtained by the implementation of the theoretical model were experimentally assessed. Ex vivo porcine liver underwent LA with tapered-tip applicator, at different laser settings (laser power of 1 W and 1.7 W, deposited energy equal to 330 J and 500 J, respectively). Almost spherical volume lesions were produced. The thermal damage was assessed by measuring the diameter of the circular-shaped lesion. The comparison between experimental results and theoretical prediction shows that the thermal damage discriminated by visual inspection always corresponds to a percentage of damaged cells of 96%. A tapered-tip applicator allows obtaining localized and reproducible damage close to spherical shape, whose diameter is related to the laser settings, and the simple theoretical model described is suitable to predict the effects, in terms of thermal damage, on ex vivo liver. Further trials should be addressed to adapt the model also on in vivo tissue, aiming to develop a tool useful to support the physician in clinical application of LA.

  20. A fiber-based implantable multi-optrode array with contiguous optical and electrical sites

    NASA Astrophysics Data System (ADS)

    Chen, Sanyuan; Pei, Weihua; Gui, Qiang; Chen, Yuanfang; Zhao, Shanshan; Wang, Huan; Chen, Hongda

    2013-08-01

    Objective. Although various kinds of optrodes are designed to deliver light and sense electrophysiological responses, few have a tightly closed optical delivering site or electrical recording site. The large space between them often blurs the stimulation location and light intensity threshold. Approach. Based on an optical fiber, we develop an optrode structure which has a coniform tip where the light exit point and gold-based electrode site are located. The optrode is fabricated by integrating a metal membrane electrode on the outside of a tapered fiber. Half of the cone-shape tip is covered by a layer of gold membrane to form the electrode. A commercial fiber connector, mechanical transfer (MT) module, is chosen to assemble the multi-optrode array (MOA). The MT connector acts as both the holder of the optrode array and an aligning part to connect the MOA with the light source. Main results. We fabricated a pluggable MOA weighing only 0.2 g. The scanning electron microscope images showed a tight cover of the metal layer on the optrode tip with an exposure area of 1500 µm2. The electrochemical impedance of the optrode at 1 kHz was 100 kΩ on average and the light emission intensity reached 13 mW. The optical modulating and electrophysiological recording ability of the MOA was validated by monitoring the response of cells in a ChR2-expressing mouse's cerebral cortex. Neurons that maintained high cluster quality (signal-to-noise ratio = 5:1) and coherence in response to trains of 20 Hz stimulation were monitored. Significance. The optrode array reduces the distance between the optical stimulating sites and electrophysiological sites dramatically and can supply multiple channels to guide different lights simultaneously. This optrode with its novel structure may lead to a different kind of optical neural control prosthetic device, opening up a new option for neural modulation in the brain.

  1. Skylight book. Capturing the Sun and the Moon: a guide to creating natural light

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burns, A.

    1976-01-01

    The following topics are covered: planning; essential tools: hand and power; safety hints; curb installation; plexiglas or plate glass skylight; the plexiglas box skylight; tips on working with plexiglas; checking for leaks; framing the shaftway; electric work; shaftwall insulation; covering the shaftway with drywall; other kinds of wall coverings; internal storm windows; plants under your skylight; skylight manufacturers; and places to buy things. There are 38 pages of pictures of the use of skylights. (MHR)

  2. Top Ten Tips for Assessing Project-Based Learning: Plus, a Bonus Tip on How to Assemble a PBL Tool Kit

    ERIC Educational Resources Information Center

    George Lucas Educational Foundation, 2011

    2011-01-01

    This classroom guide is intended to inspire and expand teachers' thinking about effective assessment in project-based learning (PBL). The tips listed in this guide are organized to follow the arc of a project. First comes planning, then the launch into active learning, and then a culminating presentation. Reflection is the final stage, and it's…

  3. The Complete Resource Guide for Summer Youth Programs. Program Ideas for Summer Youth Jobs Project Managers.

    ERIC Educational Resources Information Center

    National Alliance of Business, Inc., Washington, DC.

    This guide consists of suggestions, ideas, and tips intended to stimulate development of cooperative summer youth employment programs in local communities. Addressed in the individual sections of the guide are the following topics: tips on where to start, suggestions on how to get started, hints on securing resources, program resources, use of…

  4. Transjugular intrahepatic portosystemic shunt creation using intravascular ultrasound guidance.

    PubMed

    Farsad, Khashayar; Fuss, Cristina; Kolbeck, Kenneth J; Barton, Robert E; Lakin, Paul C; Keller, Frederick S; Kaufman, John A

    2012-12-01

    To describe the use of intravascular ultrasound (US) guidance for creation of transjugular intrahepatic portosystemic shunts (TIPSs) in humans. The initial 25 cases of intravascular US-guided TIPS were retrospectively compared versus the last 75 conventional TIPS cases during the same time period at the same institution in terms of the number of needle passes required to establish portal vein (PV) access, fluoroscopy time, and needle pass-related complications. Intravascular US-guided TIPS creation was successful in all cases, and there was no statistically significant difference in number of needle passes, fluoroscopy time, or needle pass-related complications between TIPS techniques. Intravascular US-guided TIPS creation was successful in cases in which conventional TIPS creation had failed as a result of PV thrombosis or distorted anatomy. Intravascular US guidance for TIPS creation was additionally useful in a patient with Budd-Chiari syndrome and in a patient with intrahepatic tumors. Intravascular US is a safe and reproducible means of real-time image guidance for TIPS creation, equivalent in efficacy to conventional fluoroscopic guidance. Real-time sonographic guidance with intravascular US may prove advantageous for cases in which there is PV thrombus, distorted anatomy, Budd-Chiari syndrome, or hepatic tumors. Copyright © 2012 SIR. Published by Elsevier Inc. All rights reserved.

  5. Method and apparatus for the guided ablative therapy of fast ventricular arrhythmia

    NASA Technical Reports Server (NTRS)

    Cohen, Richard J. (Inventor); Barley, Maya (Inventor)

    2010-01-01

    Method and apparatus for guiding ablative therapy of abnormal biological electrical excitation. The excitation from the previous excitatory wave is significant at the beginning of the next excitation. In particular, it is designed for treatment of fast cardiac arrhythmias. Electrical signals are acquired from recording electrodes, and an inverse dipole method is used to identify the site of origin of an arrhythmia. The location of the tip of an ablation catheter is similarly localized from signals acquired from the recording electrodes while electrical pacing energy is delivered to the tip of the catheter close to or in contact with the cardiac tissue. The catheter tip is then guided to the site of origin of the arrhythmia, and ablative radio frequency energy is delivered to its tip to ablate the site.

  6. Atmospheric turbulence compensation with laser phase shifting interferometry

    NASA Astrophysics Data System (ADS)

    Rabien, S.; Eisenhauer, F.; Genzel, R.; Davies, R. I.; Ott, T.

    2006-04-01

    Laser guide stars with adaptive optics allow astronomical image correction in the absence of a natural guide star. Single guide star systems with a star created in the earth's sodium layer can be used to correct the wavefront in the near infrared spectral regime for 8-m class telescopes. For possible future telescopes of larger sizes, or for correction at shorter wavelengths, the use of a single guide star is ultimately limited by focal anisoplanatism that arises from the finite height of the guide star. To overcome this limitation we propose to overlap coherently pulsed laser beams that are expanded over the full aperture of the telescope, traveling upwards along the same path which light from the astronomical object travels downwards. Imaging the scattered light from the resultant interference pattern with a camera gated to a certain height above the telescope, and using phase shifting interferometry we have found a method to retrieve the local wavefront gradients. By sensing the backscattered light from two different heights, one can fully remove the cone effect, which can otherwise be a serious handicap to the use of laser guide stars at shorter wavelengths or on larger telescopes. Using two laser beams multiconjugate correction is possible, resulting in larger corrected fields. With a proper choice of laser, wavefront correction could be expanded to the visible regime and, due to the lack of a cone effect, the method is applicable to any size of telescope. Finally the position of the laser spot could be imaged from the side of the main telescope against a bright background star to retrieve tip-tilt information, which would greatly improve the sky coverage of the system.

  7. Evaluation of a novel, ultrathin, tip-bending endoscope in a synthetic force-sensing pancreas with comparison to medical guide wires

    PubMed Central

    Chandler, John E; Lee, Cameron M; Babchanik, Alexander P; Melville, C David; Saunders, Michael D; Seibel, Eric J

    2012-01-01

    Purpose Direct visualization of pancreatic ductal tissue is critical for early diagnosis of pancreatic diseases and for guiding therapeutic interventions. A novel, ultrathin (5 Fr) scanning fiber endoscope (SFE) with tip-bending capability has been developed specifically to achieve high resolution imaging as a pancreatoscope during endoscopic retrograde cholangiopancreatography (ERCP). This device has potential to dramatically improve both diagnostic and therapeutic capabilities during ERCP by providing direct video feedback and tool guidance to clinicians. Methods Invasiveness of the new tip-bending SFE was evaluated by a performance comparison to ERCP guide wires, which are routinely inserted into the pancreatic duct during ERCP. An in vitro test model with four force sensors embedded in a synthetic pancreas was designed to detect and compare the insertion forces for 0.89 mm and 0.53 mm diameter guide wires as well as the 1.7 mm diameter SFE. Insertions were performed through the working channel of a therapeutic duodenoscope for the two types of guide wires and using a statistically similar direct insertion method for comparison to the SFE. Results Analysis of the forces detected by the sensors showed the smaller diameter 0.53 mm wire produced significantly less average and maximum forces during insertion than the larger diameter 0.89 mm wire. With the use of tip-bending and optical visualization, the 1.7 mm diameter SFE produced significantly less average force during insertion than the 0.89 mm wire at every sensor, despite its larger size. It was further shown that the use of tip-bending with the SFE significantly reduced the forces at all sensors, compared to insertions when tip-bending was not used. Conclusion Combining high quality video imaging with two-axis tip-bending allows a larger diameter guide wire-style device to be inserted into the pancreatic duct during ERCP with improved capacity to perform diagnostics and therapy. PMID:23166452

  8. Light production by the arm tips of the deep-sea cephalopod Vampyroteuthis infernalis.

    PubMed

    Robison, Bruce H; Reisenbichler, Kim R; Hunt, James C; Haddock, Steven H D

    2003-10-01

    The archaic, deep-sea cephalopod Vampyroteuthis infernalis occurs in dark, oxygen-poor waters below 600 m off Monterey Bay, California. Living specimens, collected gently with a remotely operated vehicle (ROV) and quickly transported to a laboratory ashore, have revealed two hitherto undescribed means of bioluminescent expression for the species. In the first, light is produced by a new type of organ located at the tips of all eight arms. In the second, a viscous fluid containing microscopic luminous particles is released from the arm tips to form a glowing cloud around the animal. Both modes of light production are apparently linked to anti-predation strategies. Use of the tip-lights is readily educed by contact stimuli, while fluid expulsion has a much higher triggering threshold. Coelenterazine and luciferase are the chemical precursors of light production. This paper presents observations on the structure and operation of the arm-tip light organs, the character of the luminous cloud, and how the light they produce is incorporated into behavioral patterns.

  9. Lighting: Traffic Safety Tips

    DOT National Transportation Integrated Search

    1996-01-01

    This fact sheet, NHTSA Facts: Summer 1996, discusses traffic safety tips on motor vehicle lighting, including headlights, tail lights, and signal lights. It details the cleaning of headlamps, proper aiming of headlamps, and replacement of burned out ...

  10. A fiberoptic reflection oximeter.

    PubMed

    Landsman, M L; Knop, N; Kwant, G; Mook, G A; Zijlstra, W G

    1978-03-20

    A catheter tip oximeter is described consisting of a cardiac catheter containing optical fibers, and incandescent light source, a light detection unit and a processing unit. Half of the optical fibers guide the light to the blood at the tip of the catheter, the other half the backscattered (reflected) light to the detection unit. The detection unit contains a dichroic mirror, transmitting most of the light with lambda less than 800 nm and reflecting most of the light with lambda greater than 900 nm, thus splitting the light into two beams. These pass through interference filters with nominal wavelengths of 640 and 920 nm respectively, and are focused on silicium barrier layer photocells. The photocell signals are amplified and fed into a divider giving the ratio of measuring (R640) and compensating (R920) photocell output. The relationship between log R640/R920 and oxygen saturation is represented by a slightly curved line. The relation may be linearized by subtracting a constant voltage from the divided output before taking the logarithm. The slope of the calibration line is dependent on the total haemoglobin concentration. Nonetheless an average calibration line can be used between 70 and 100% oxygen saturation. For 78 measurements of pig blood samples in this range (haemoglobin concentration between 96 and 161 g.1(-1)), the standard deviation of the difference between the fiberoptic oximeter and a Radiometer OSM1 oxygen saturation meter was 1.9% saturation, for 152 samples over the entire saturation range the standard deviation of the difference was 3.1% saturation. The influence of the flow velocity of blood on the light reflection depends on wavelength as well as on oxygen saturation. Therefore, complete compensation for the flow effect is not possible by simple means.

  11. Tip-enhanced Raman spectroscopy and near-field polarization

    NASA Astrophysics Data System (ADS)

    Saito, Yuika; Mino, Toshihiro; Verma, Prabhat

    2015-12-01

    Tip-enhanced Raman spectroscopy (TERS) is a powerful tool for High-resolution Raman spectroscopy. In this method, a metal coated nano-tip acts as a plasmonic antenna to enhance the originally weak Raman scattering from a nanometric volume of a sample. The technique enables to detect Raman scattering light from nano-scale area and also enhance the light intensity with combination of near-filed light and localized surface plasmon generated at a metallized tip apex. Nowadays TERS is used to investigate various nano-scale samples, for examples, carbon nanotubes, graphenes DNA and biomaterials. As the TERS developed, there is high demand to investigate the properties of near-field light e.g. polarization properties. We have analyzed the polarization properties of near-field light in TERS and successfully realized the quantitative nano-imaging by visible light.

  12. Staff Training Tips: Focusing on Early Childhood Education and Services.

    ERIC Educational Resources Information Center

    2003

    This document collects 15 brief guides to staff training in inclusive early childhood education settings. Guides offer examples of successful programs, research findings, and practical tips. Titles are: (1) "Giving Families Better Access to Early Intervention Services"; (2) "Creating Integrated Classrooms that Work"; (3) "Seamless Transition…

  13. Status and new developments with the Keck I near-infrared tip-tilt sensor

    NASA Astrophysics Data System (ADS)

    Femenía Castellá, Bruno; Wizinowich, Peter; Rampy, Rachel; Cetre, Sylvain; Lilley, Scott; Lyke, Jim; Ragland, Sam; Stomski, Paul; van Dam, Marcos

    2016-07-01

    The sky coverage and performance of Laser Guide Star (LGS) adaptive optics (AO) systems is limited by the Natural Guide Star (NGS) used for low order correction (tip-tilt and defocus modes). This limitation can be reduced by measuring image motion of the NGS in the near-infrared where it is partially corrected by the LGS AO system and where stars are generally several magnitudes brighter than at visible wavelengths. We have integrated a Near-InfraRed Tip-Tilt Sensor (NIRTTS) with the Keck I telescopes LGS AO system. The sensor is a H2RG-based near-infrared camera with 0.05 arcsecond pixels. Low noise at high sample rates is achieved by only reading a small region of interest, from 2x2 to 16x16 pixels, centered on an NGS anywhere in an 100 arc second diameter field. The sensor operates at either Ks or H-band using light reflected by a choice of dichroic beam-splitters located in front of the OSIRIS integral field spectrograph. The implementation of the NIRTTS involved modifications to the AO bench, real-time control system, higher-level controls and operations software. NIRTTS is nearly ready for science operation in shared-risk mode. We are also implementing a number of enhancements to the NIRTTS system which involve substantial changes to the operations software. This work presents an update of the work performed since the NIRTTS system was reported in Ref. 1 and Ref. 2.

  14. Effect of LED-LCU light irradiance distribution on mechanical properties of resin based materials.

    PubMed

    Magalhães Filho, T R; Weig, K M; Costa, M F; Werneck, M M; Barthem, R B; Costa Neto, C A

    2016-06-01

    The objective of this study is to analyze the light power distribution along the tip end of the light guide of three LED-LCUs (Light Curing Units) and to evaluate its effect on the mechanical properties of a polymer based dental composite. Firstly, the light power distribution over the whole area of LED-LCU light guide surface was analyzed by three methods: visual projection observation, spectral measurement and optical spectral analysis (OSA). The light power distribution and the total irradiance were different for the three LEDs used, but the wavelength was within the camphorquinone absorption spectrum. The use of a blank sheet was quite on hand to make a qualitative analysis of a beam, and it is costless. Secondly, specimens of a hybrid composite with approximately 8mm diameter and 2mm thickness were produced and polymerized by 20s exposition time to each LED-LCU. Thirdly, the elastic modulus (E) and hardness (HV) were measured throughout the irradiated area by instrumented micro-indentation test (IIT), allowing to correlate localized power and mechanical properties. Both E and HV showed to be very sensitive to local power and wavelength dependent, but they followed the beam power profile. It was also shown that the mechanical properties could be directly correlated to the curing process. Very steep differences in mechanical properties over very short distances may impair the material performance, since residual stresses can easily be built over it. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. Optical probe for determining the fat/lean interface in cuts of meat

    DOEpatents

    Weber, Thomas M.; Callow, Diane S.; Jones, James F.; Kuehl, Michael A.; Spletzer, Barry L.

    2005-02-22

    An apparatus and method for locating the boundary surface between a layer of fatty tissue and lean tissue in a cut of meat, such as beef, such as slabs of meat undergoing trimming and cutting in commercial meet processing facilitates. The invention exploits the fact that fatty tissue and lean tissue have significantly different responses to incident light energy. By gauging the degree to which a generated beam of light is scattered and reflected by the tissues under evaluation, the invention permits the character of the tissue to be ascertained. An incident beam of light, such as green light, is generated and transmitted to a probe tip, which tip is inserted into the cut of meat under investigation. The light beam is emitted into the meat tissues from the probe tip, and then is scattered and reflected by the tissues, whereupon some fraction of the emitted light returns to the probe tip. The returning light energy is transmitted to a detector; relative changes in the returning light transmitted to the detector permit the operator to determine when the probe tip is approaching or penetrating the fat/lean tissue interface.

  16. Investigation of Blade-row Flow Distributions in Axial-flow-compressor Stage Consisting of Guide Vanes and Rotor-blade Row

    NASA Technical Reports Server (NTRS)

    Mahoney, John J; Dugan, Paul D; Budinger, Raymond E; Goelzer, H Fred

    1950-01-01

    A 30-inch tip-diameter axial-flow compressor stage was investigated with and without rotor to determine individual blade-row performance, interblade-row effects, and outer-wall boundary-layer conditions. Velocity gradients at guide-vane outlet without rotor approximated design assumptions, when the measured variation of leaving angle was considered. With rotor in operation, Mach number and rotor-blade effects changed flow distribution leaving guide vanes and invalidated design assumption of radial equilibrium. Rotor-blade performance correlated interpolated two-dimensional results within 2 degrees, although tip stall was indicated in experimental and not two-dimensional results. Boundary-displacement thickness was less than 1.0 and 1.5 percent of passage height after guide vanes and after rotor, respectively, but increased rapidly after rotor when tip stall occurred.

  17. Design of an Optically Controlled MR-Compatible Active Needle

    PubMed Central

    Ryu, Seok Chang; Quek, Zhan Fan; Koh, Je-Sung; Renaud, Pierre; Black, Richard J.; Moslehi, Behzad; Daniel, Bruce L.; Cho, Kyu-Jin; Cutkosky, Mark R.

    2015-01-01

    An active needle is proposed for the development of magnetic resonance imaging (MRI)-guided percutaneous procedures. The needle uses a low-transition-temperature shape memory alloy (LT SMA) wire actuator to produce bending in the distal section of the needle. Actuation is achieved with internal optical heating using laser light transported via optical fibers and side coupled to the LT SMA. A prototype, with a size equivalent to a standard 16-gauge biopsy needle, exhibits significant bending, with a tip deflection of more than 14° in air and 5° in hard tissue. A single-ended optical sensor with a gold-coated tip is developed to measure the curvature independently of temperature. The experimental results in tissue phantoms show that human tissue causes fast heat dissipation from the wire actuator; however, the active needle can compensate for typical targeting errors during prostate biopsy. PMID:26512231

  18. Clinical evaluation of the use of an intracardiac electrocardiogram to guide the tip positioning of peripherally inserted central catheters.

    PubMed

    Zhao, Ruiyi; Chen, Chunfang; Jin, Jingfen; Sharma, Komal; Jiang, Nan; Shentu, Yingqin; Wang, Xingang

    2016-06-01

    The use of peripherally inserted central catheters (PICCs) provides important central venous accesses for clinical treatments, tests and monitoring. Compared with the traditional methods, intracardiac electrocardiogram (ECG)-guided method has the potential to guide more accurate tip positioning of PICCs. This study aimed to clinically evaluate the effectiveness of an intracardiac ECG to guide the tip positioning by monitoring characteristic P-wave changes. In this study, eligible patients enrolled September 2011 to May 2012 according to the inclusion and exclusion criteria received the catheterization monitored by intracardiac ECG. Then chest radiography was performed to check the catheter position. The results revealed that, with 117 eligible patients, all bar one patient who died (n = 116) completed the study, including 60 males and 56 females aged 51.2 ± 15.1 years. Most (n = 113, > 97%) had characteristic P-wave changes. The intracardiac ECG-guided positioning procedure achieved correct placement for 112 patients (96.56%), demonstrating 99.12% sensitivity and 100% specificity. In conclusion, the intracardiac ECG can be a promising technique to guide tip positioning of PICCs. However, since the sample size in this study is limited, more experience and further study during clinical practice are needed to demonstrate achievement of optimal catheterization outcomes. © 2015 John Wiley & Sons Australia, Ltd.

  19. Evaluation of range and distortion tolerance for high Mach number transonic fan stages. Task 2: Performance of a 1500-foot-per-second tip speed transonic fan stage with variable geometry inlet guide vanes and stator

    NASA Technical Reports Server (NTRS)

    Bilwakesh, K. R.; Koch, C. C.; Prince, D. C.

    1972-01-01

    A 0.5 hub/tip radius ratio compressor stage consisting of a 1500 ft/sec tip speed rotor, a variable camber inlet guide vane and a variable stagger stator was designed and tested with undistorted inlet flow, flow with tip radial distortion, and flow with 90 degrees, one-per-rev, circumferential distortion. At the design speed and design IGV and stator setting the design stage pressure ratio was achieved at a weight within 1% of the design flow. Analytical results on rotor tip shock structure, deviation angle and part-span shroud losses at different operating conditions are presented. The variable geometry blading enabled efficient operation with adequate stall margin at the design condition and at 70% speed. Closing the inlet guide vanes to 40 degrees changed the speed-versus-weight flow relationship along the stall line and thus provided the flexibility of operation at off-design conditions. Inlet flow distortion caused considerable losses in peak efficiency, efficiency on a constant throttle line through design pressure ratio at design speed, stall pressure ratio, and stall margin at the 0 degrees IGV setting and high rotative speeds. The use of the 40 degrees inlet guide vane setting enabled partial recovery of the stall margin over the standard constant throttle line.

  20. Thermal injury secondary to laparoscopic fiber-optic cables.

    PubMed

    Hindle, A Katharine; Brody, Fred; Hopkins, Vernon; Rosales, Greg; Gonzalez, Florencia; Schwartz, Arnold

    2009-08-01

    Laparoscopy requires a reliable light source to provide adequate visualization. However, thermal energy is produced as a by-product from the optical cable. This study attempts to quantify the degree of possible thermal damage secondary to the fiber-optic light source. Using a digital thermometer, temperature measurements were recorded at the tip of optical cables from five different light sources (Karl Storz, Inc., Tuttlingen, Germany). Temperature measurements were recorded with new and old bulbs. The tip of the cable was applied to surgical drapes and the time to charring was recorded. Subsequently, the tip of the optical cable was applied to a porcine model and tissue samples were obtained after varying amounts of time (5, 15, 30, 60, and 90 s). Sections of the damaged tissue were prepared for microscopic evaluation. Parameters for thermal injury included extent of epidermal, dermal, and subcutaneous fat damage and necrosis. The lateral extent and depth of injury were measured. The maximum temperature at the tip of the optical cable varied between 119.5 degrees C and 268.6 degrees C. When surgical drapes were exposed to the tip of the light source, the time to char was 3-6 s. The degree and volume of injury increased with longer exposure times, and significant injury was recorded with the optical cable 3 mm from the skin. This study demonstrates that the temperature at the tip of the optical light cord can induce extensive damage. The by-product of light, heat, can produce immediate superficial tissue necrosis that can extend into the subcutaneous fat even when the optical tip is not in direct contact with the skin. In addition, our study shows the variation in temperature that exists between light sources and bulb status. Overall, surgeons must realize and respect the potential complications associated with optical technology.

  1. Trade-offs between light interception and leaf water shedding: a comparison of shade- and sun-adapted species in a subtropical rainforest.

    PubMed

    Meng, Fengqun; Cao, Rui; Yang, Dongmei; Niklas, Karl J; Sun, Shucun

    2014-01-01

    Species in high-rainfall regions have two major alternative approaches to quickly drain off water, i.e., increasing leaf inclination angles relative to the horizontal plane, or developing long leaf drip tips. We hypothesized that shade-adapted species will have more pronounced leaf drip tips but not greater inclination angles (which can reduce the ability to intercept light) compared to sun-adapted species and that length of leaf drip tips will be negatively correlated with photosynthetic capacity [characterized by light-saturated net photosynthetic rates (Amax), associated light compensation points (LCP), and light saturation points (LSP)]. We tested this hypothesis by measuring morphological and physiological traits that are associated with light-interception and water shedding for seven shade-adapted shrub species, ten sun-adapted understory shrub species, and 15 sun-adapted tree species in a subtropical Chinese rainforest, where mean annual precipitation is around 1,600 mm. Shade-adapted understory species had lower LMA, Amax, LSP, and LCP compared to understory or canopy sun-adapted species; their leaf and twig inclination angles were significantly smaller and leaf drip tips were significantly longer than those in sun-adapted species. This suggests that shade-adapted understory species tend to develop pronounced leaf drip tips but not large leaf inclination angles to shed water. The length of leaf drip tips was negatively correlated with leaf inclination angles and photosynthetic capacity. These relationships were consistent between ordinary regression and phylogenetic generalized least squares analyses. Our study illustrates the trade-offs between light interception and leaf water shedding and indicates that length of leaf drip tips can be used as an indicator of adaptation to shady conditions and overall photosynthetic performance of shrub species in subtropical rainforests.

  2. Bisphenol A release from an orthodontic adhesive and its correlation with the degree of conversion on varying light-curing tip distances.

    PubMed

    Sunitha, Catherine; Kailasam, Vignesh; Padmanabhan, Sridevi; Chitharanjan, Arun B

    2011-08-01

    The aims of this research were to use high-performance liquid chromatography to assess the bisphenol A (BPA) released from an orthodontic adhesive (Transbond XT; 3M Unitek, Monrovia, Calif) with various light-curing tip distances and to correlate the release to the degree of conversion. One hundred thirty-eight premolar brackets were divided into 3 groups of 40 each for the high-performance liquid chromatography analysis and 3 groups of 6 each for assessing the degree of conversion. Fourier transform infrared spectroscopy was used for this purpose. Each group was studied at light-curing tip distances of 0, 5, and 10 mm. Statistical analyses were performed by using 2-way analysis of variance (ANOVA), post-hoc multiple comparisons Tukey HSD tests, and paired t tests. Pearson correlation was used to assess the correlation between the degree of conversion and BPA release. BPA release was greater in specimens cured with a greater light-curing tip distance. The degree of conversion decreased with increased light-curing tip distances. A negative correlation was found between BPA release and degree of conversion. Clinicians should ensure that the adhesive is completely cured by keeping the light-curing tip as close to the adhesive as clinically possible. Copyright © 2011 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  3. The TMT Adaptive Optics Program

    NASA Astrophysics Data System (ADS)

    Ellerbroek, Brent

    2011-09-01

    We provide an overview of the Thirty Meter Telescope (TMT) AO program, with an emphasis upon the progress made since the first AO4ELT conference held in 2009. The first light facility AO system for TMT is the Narrow Field Infra-Red AO System (NFIRAOS), which will provide diffraction-limited performance in the J, H, and K bands over 18-30 arc sec diameter fields with 50% sky coverage at the galactic pole. This is accomplished with order 60x60 wavefront sensing and correction, two deformable mirrors conjugate to ranges of 0 and 11.2 km, 6 sodium laser guide stars in an asterism with a diameter of 70 arc sec, and three low order (tip/tilt or tip/tilt focus), infra-red natural guide star (NGS) wavefront sensors deployable within a 2 arc minute diameter patrol field. The first light LGS asterism is generated by the Laser Guide Star Facility (LGSF), which initially incorporates 6 20-25W class laser systems mounted to the telescope elevation journal, a mirror-based beam transfer optics system, and a 0.4m diameter laser launch telescope located behind the TMT secondary mirror. Future plans for additional AO capabilities include a mid infra-red AO (MIRAO) system to support science instruments in the 4-20 micron range, a ground-layer AO (GLAO) system for wide-field spectroscopy, a multi-object AO (MOAO) system for multi-object integral field unit spectroscopy, and extreme AO (ExAO) for high contrast imaging. Significant progress has been made in developing the first-light AO architecture since 2009. This includes the adoption of a new NFIRAOS opto-mechanical design consisting of two off-axis parabola (OAP) relays in series, which eliminates field distortion and also significantly simplifies the designs of the LGS wavefront sensors, optical source simulators, and turbulence generator subsystem. The design of the LGSF has also been interated, and has been simplfied by the relocation of the (smaller, gravity invarient) laser systems to the telescope elevation journal. Protoyping activities continue for laser systems, wavefront sensing detectors, and deformable mirrors; work on the associated detector and deformable mirror electronics has also been initiated. AO Performance estimates and error budgets have been further detailed. Some of the modeling topics which have received particular attention include turbulence (Cn2) profile estimation from LGS WFS measurements, sodium layer range tracking, PSF reconstruction for multi-conjugate AO, LGS fratricide, astrometry at the galactic center, and further optimizing sky coverage and the peformance of the tip/tilt and low-order NGS mode control loops. Finally, experiments and field tests continue at the University of British Columbia LIDAR facility to measure the spatial and temporal variability of the sodium layer, and to characterize the sodium coupling efficiency of candidate laser systems for TMT.

  4. Radiofrequency Wire Recanalization of Chronically Thrombosed TIPS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Majdalany, Bill S., E-mail: bmajdala@med.umich.edu; Elliott, Eric D., E-mail: eric.elliott@osumc.edu; Michaels, Anthony J., E-mail: Anthony.michaels@osumc.edu

    Radiofrequency (RF) guide wires have been applied to cardiac interventions, recanalization of central venous thromboses, and to cross biliary occlusions. Herein, the use of a RF wire technique to revise chronically occluded transjugular intrahepatic portosystemic shunts (TIPS) is described. In both cases, conventional TIPS revision techniques failed to revise the chronically thrombosed TIPS. RF wire recanalization was successfully performed through each of the chronically thrombosed TIPS, demonstrating initial safety and feasibility in this application.

  5. Radially leaned outlet guide vanes for fan source noise reduction

    NASA Technical Reports Server (NTRS)

    Kazin, S. B.

    1973-01-01

    Two quiet engine program half scale fans one with a subsonic and the other with a supersonic fan tip speed at takeoff were run with 30 degree leaned and radial outlet guide vanes. Acoustic data at takeoff fan speed on the subsonic tip speed fan showed decreases in 200-foot sideline noise of from 1 to 2 PNdb. The supersonic tip speed fan a takeoff fan speed, however, showed noise increases of up 3 PNdb and a decrease in fan efficiency. At approach fan speed, the subsonic tip speed fan showed a noise decrease of 2.3 PNdb at the 200-foot sideline maximum angle and an increase in efficiency. The supersonic tip speed fan showed noise increase of 3.5 PNdb and no change in efficiency. The decrease in fan efficiency and the nature of the noise increase largely high frequency broadband noise lead to the speculation that an aerodynamic problem occurred.

  6. A novel tunable white light emitting multiphase phosphor obtained from Ba2TiP2O9 by introducing Eu3+

    NASA Astrophysics Data System (ADS)

    Zhou, Zhenzhen; Liu, Guanghui; Wan, Jieqiong; Ni, Jia; Lu, Zhouguang; Ma, Ruguang; Zhou, Yao; Wang, Jiacheng; Liu, Qian

    2016-04-01

    Tunable white light was realized in samples Ba2(1- x)TiP2O9:2 xEu ( x = 0-0.80) by introducing orange-red light emitting Eu3+ in self-activated blue-green light emitting matrix Ba2TiP2O9. The sample Ba2(1- x)TiP2O9:2 xEu is a multiphase system consisting of Ba2TiP2O9, EuPO4 and TiO2 when x is greater than or equal to 0.20. The tunable light from blue-green to bluish-white, to white, and eventually to pinky-white of samples Ba2(1- x)TiP2O9:2 xEu under UV light excitation is attributed to the light mixture of tunable blue-green light from Ti4+-O2- charge transfer transition in Ba2TiP2O9 and orange-red light from Eu3+ 4f-4f transition mostly in EuPO4. The Commission International de l'Eclairage chromaticity coordinates, correlated color temperature and color rendering index were tuned from (0.262, 0.339), 9492 K and 74 for matrix sample Ba2TiP2O9 to (0.324, 0.346), 5876 K and 87 for sample Ba2(1- x)TiP2O9:2 xEu ( x = 0.40) under UV light excitation. Therefore, a kind of promising UV-excited white light emitting multiphase phosphor was obtained.

  7. Effectiveness of electrocardiographic guidance in CVAD tip placement.

    PubMed

    Walker, Graham; Chan, Raymond J; Alexandrou, Evan; Webster, Joan; Rickard, Claire

    International standard practice for the correct confirmation of the central venous access device is the chest X-ray. The intracavitary electrocardiogram-based insertion method is radiation-free, and allows real-time placement verification, providing immediate treatment and reduced requirement for post-procedural repositioning. Relevant databases were searched for prospective randomised controlled trials (RCTs) or quasi RCTs that compared the effectiveness of electrocardiogram-guided catheter tip positioning with placement using surface-anatomy-guided insertion plus chest X-ray confirmation. The primary outcome was accurate catheter tip placement. Secondary outcomes included complications, patient satisfaction and costs. Five studies involving 729 participants were included. Electrocardiogram-guided insertion was more accurate than surface anatomy guided insertion (odds ratio: 8.3; 95% confidence interval (CI) 1.38; 50.07; p=0.02). There was a lack of reporting on complications, patient satisfaction and costs. The evidence suggests that intracavitary electrocardiogram-based positioning is superior to surface-anatomy-guided positioning of central venous access devices, leading to significantly more successful placements. This technique could potentially remove the requirement for post-procedural chest X-ray, especially during peripherally inserted central catheter (PICC) line insertion.

  8. Ahorre Energia: Consejos sobre el ahorro de dinero y energia en el hogar (Book)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    Learn how to save money with Energy Saver: Tips on Saving Money & Energy at Home, from the U.S. Department of Energy. The Energy Saver guide will help you reduce your monthly energy costs and live more efficiently. This guide takes you through the systems and appliances that consume the most energy in your home, and provides solutions to cut costs for you while saving the environment. The Energy Saver guide also includes transportation tips to help you save money at the pump.

  9. Corrugated metal-coated tapered tip for scanning near-field optical microscope.

    PubMed

    Antosiewicz, Tomasz J; Szoplik, Tomasz

    2007-08-20

    This paper addresses an important issue of light throughput of a metal-coated tapered tip for scanning near-field microscope (SNOM). Corrugations of the interface between the fiber core and metal coating in the form of parallel grooves of different profiles etched in the core considerably increase the energy throughput. In 2D FDTD simulations in the Cartesian coordinates we calculate near-field light emitted from such tips. For a certain wavelength range total intensity of forward emission from the corrugated tip is 10 times stronger than that from a classical tapered tip. When realized in practice the idea of corrugated tip may lead up to twice better resolution of SNOM.

  10. Sprouting angiogenesis in human midterm uterus and fallopian tube is guided by endothelial tip cells.

    PubMed

    Rusu, M C; Motoc, A G M; Pop, F; Folescu, R

    2013-01-01

    Five samples of human midterm fetal uterus and fallopian tube (four donor bodies) were used to assess whether or not processes of angiogenesis are guided by endothelial tip cells (ETCs), and if cytokine-receptors, such as CD117/c-kit and PDGFR-α, are expressed in the microenvironment of the endothelial tubes. CD34 labeled microvessels in the uterine wall (myometrium and endometrium) and in the wall of the uterine (fallopian) tube, and accurately identified ETCs in both organs. We conclude that sprouting angiogenesis in the developing human female tract is guided by ETCs. Moreover, CD117/c-kit antibodies labeled mural networks of pericytes, α-SMA-positive and desmin-negative, related to the endometrial (but not myometrial) microvessels, and similar labeling was identified in the wall of the uterine tube. PDGFR-α positive labeling, stromal and pericytary, was also found. Thus, sprouting angiogenesis in human fetal genital organs appears to be guided by tip cells and is influenced by tyrosine kinase receptor signaling.

  11. Intravascular Ultrasound in the Creation of Transhepatic Portosystemic Shunts Reduces Needle Passes, Radiation Dose, and Procedure Time: A Retrospective Study of a Single-Institution Experience.

    PubMed

    Kao, Steven D; Morshedi, Maud M; Narsinh, Kazim H; Kinney, Thomas B; Minocha, Jeet; Picel, Andrew C; Newton, Isabel; Rose, Steven C; Roberts, Anne C; Kuo, Alexander; Aryafar, Hamed

    2016-08-01

    To assess whether intravascular ultrasound (US) guidance impacts number of needle passes, contrast usage, radiation dose, and procedure time during creation of transjugular intrahepatic portosystemic shunts (TIPS). Intravascular US-guided creation of TIPS in 40 patients was retrospectively compared with conventional TIPS in 49 patients between February 2010 and November 2015 at a single tertiary care institution. Patient sex and age, etiology of liver disease (hepatitis C virus, alcohol abuse, nonalcoholic steatohepatitis), severity of liver disease (mean Model for End-Stage Liver Disease score), and indications for TIPS (variceal bleeding, refractory ascites, refractory hydrothorax) in conventional and intravascular US-guided cases were recorded. The two groups were well matched by sex, age, etiology of liver disease, Child-Pugh class, Model for End-Stage Liver Disease scores, and indication for TIPS (P range = .19-.94). Fewer intrahepatic needle passes were required in intravascular US-guided TIPS creation compared with conventional TIPS (2 passes vs 6 passes, P < .01). Less iodinated contrast material was used in intravascular US cases (57 mL vs 140 mL, P < .01). Radiation exposure, as measured by cumulative dose, dose area product, and fluoroscopy time, was reduced with intravascular US (174 mGy vs 981 mGy, P < .01; 3,793 μGy * m(2) vs 21,414 μGy * m(2), P < .01; 19 min vs 34 min, P < .01). Procedure time was shortened with intravascular US (86 min vs 125 min, P < .01). Intravascular US guidance resulted in fewer intrahepatic needle passes, decreased contrast medium usage, decreased radiation dosage, and shortened procedure time in TIPS creation. Copyright © 2016 SIR. All rights reserved.

  12. Tip-leakage cavitation in the clearance of a 2D hydrofoil with fillets: high-speed visualization and PIV/PTV measurements

    NASA Astrophysics Data System (ADS)

    Zapryagaev, Ivan I.; Timoshevskiy, Mikhail V.; Pervunin, Konstantin S.

    2017-09-01

    Tip-clearance cavitation is one of the most aggressive forms of cavitation as it can cause surface erosion of hydraulic machinery elements and, as a result, their fatigue damage and disturb designed operating conditions. At present, the literature lacks for detailed experimental data on the inception and development of this type of cavitation at various flow conditions. In the paper, a tip-leakage cavitation occurring in the clearance between an end face of a 2D hydrofoil (a scaled-down model of guide vanes (GV) of a Francis turbine) and a transparent wall of the test section was studied. The experiments were carried out for different cavitating regimes on the cavitation number and two attack angles of 3° and 9°, with the gap size (tip clearance width) varied in the range from 0.4 to 0.8 mm. In order to determine the cavitation inception conditions and investigate the dynamics of the tip-leakage cavitation, a high-speed visualization was applied. A modified PIV/PTV technique with a diverging laser beam instead of a laser light sheet was used to measure the mean velocity distributions within the gap. It was shown that the cavitation pattern on the suction side of the GV model impacts the dynamics of the leakage flow in the gap but does not affect the sheet cavity formed close to the foil leading edge in the clearance as well as its size and dynamics. When the gap size is increased, the tip-leakage cavitation initiates at higher cavitation numbers or, in other words, conditions for the cavitation occurrence become more favorable.

  13. Cylindrically distributing optical fiber tip for uniform laser illumination of hollow organs

    NASA Astrophysics Data System (ADS)

    Buonaccorsi, Giovanni A.; Burke, T.; MacRobert, Alexander J.; Hill, P. D.; Essenpreis, Matthias; Mills, Timothy N.

    1993-05-01

    To predict the outcome of laser therapy it is important to possess, among other things, an accurate knowledge of the intensity and distribution of the laser light incident on the tissue. For irradiation of the internal surfaces of hollow organs, modified fiber tips can be used to shape the light distribution to best suit the treatment geometry. There exist bulb-tipped optical fibers emitting a uniform isotropic distribution of light suitable for the treatment of organs which approximate a spherical geometry--the bladder, for example. For the treatment of organs approximating a cylindrical geometry--e.g. the oesophagus--an optical fiber tip which emits a uniform cylindrical distribution of light is required. We report on the design, development and testing of such a device, the CLD fiber tip. The device was made from a solid polymethylmethacrylate (PMMA) rod, 27 mm in length and 4 mm in diameter. One end was shaped and 'silvered' to form a mirror which reflected the light emitted from the delivery fiber positioned at the other end of the rod. The shape of the mirror was such that the light fell with uniform intensity on the circumferential surface of the rod. This surface was coated with BaSO4 reflectance paint to couple the light out of the rod and onto the surface of the tissue.

  14. Development of Active Catheter,Active Guide Wire and Micro Sensor Systems

    PubMed Central

    Haga, Y.; Mineta, T.; Totsu, K.; Makishi, W.; Esashi, M.

    2001-01-01

    Summary Active catheters and active guide wires which move like a snake have been developed for catheter-based minimally invasive diagnosis and therapy. Communication and control IC chips in the active catheter reduce the number of lead wires for control. The active catheter can be not only bent but also torsioned and extended. An ultra minature fiber-optic pressure sensor; a forward-looking ultrasonic probe and a magnetic position and orientation sensor have been developed for catheters and guide wires. These moving mechanisms and several sensors which are fitted near the tip of the catheter and the guide wire will provide detailed information near the tip and enable delicate and effective catheter intervention. PMID:20663389

  15. Intrauterine device for laser light diffusion and method of using the same

    DOEpatents

    Tadir, Yona; Berns, Michael W.; Svaasand, Lars O.; Tromberg, Bruce J.

    1995-01-01

    An improved device for delivery of photoenergy from a light source, such as a laser, into a uterine cavity for photodynamic therapy is comprised of a plurality of optic fibers, which are bundled together and inserted into the uterine cavity by means of a uterine cannula. The cannula is positioned within the uterine cavity at a preferred location and then withdrawn thereby allowing the plurality of optic fibers to splay or diverge one from the other within the cavity. Different portions of the distal tip of the optic fiber is provided with a light diffusing tip, the remainder being provided with a nondiffusing tip portion. The fiber optic shape, as well as the segment which is permitted to actively diffuse light through the tip, is selected in order to provide a more uniform exposure intensity of the photo energy or at least sufficient radiation directed to each segment of the uterine walls.

  16. Intrauterine device for laser light diffusion and method of using the same

    DOEpatents

    Tadir, Y.; Berns, M.W.; Svaasand, L.O.; Tromberg, B.J.

    1995-12-26

    An improved device for delivery of photoenergy from a light source, such as a laser, into a uterine cavity for photodynamic therapy is comprised of a plurality of optic fibers, which are bundled together and inserted into the uterine cavity by means of a uterine cannula. The cannula is positioned within the uterine cavity at a preferred location and then withdrawn thereby allowing the plurality of optic fibers to splay or diverge one from the other within the cavity. Different portions of the distal tip of the optic fiber is provided with a light diffusing tip, the remainder being provided with a nondiffusing tip portion. The fiber optic shape, as well as the segment which is permitted to actively diffuse light through the tip, is selected in order to provide a more uniform exposure intensity of the photo energy or at least sufficient radiation directed to each segment of the uterine walls. 5 figs.

  17. Method for nanoscale spatial registration of scanning probes with substrates and surfaces

    NASA Technical Reports Server (NTRS)

    Wade, Lawrence A. (Inventor)

    2010-01-01

    Embodiments in accordance with the present invention relate to methods and apparatuses for aligning a scanning probe used to pattern a substrate, by comparing the position of the probe to a reference location or spot on the substrate. A first light beam is focused on a surface of the substrate as a spatial reference point. A second light beam then illuminates the scanning probe being used for patterning. An optical microscope images both the focused light beam, and a diffraction pattern, shadow, or light backscattered by the illuminated scanning probe tip of a scanning probe microscope (SPM), which is typically the tip of the scanning probe on an atomic force microscope (AFM). Alignment of the scanning probe tip relative to the mark is then determined by visual observation of the microscope image. This alignment process may be repeated to allow for modification or changing of the scanning probe microscope tip.

  18. Energy Efficiency and Renewable Energy in SIPs and TIPs

    EPA Pesticide Factsheets

    Tools and guides to encourage state, tribal and local agencies to consider incorporating Energy Efficiency (EE) and Renewable Energy (RE) policies and programs in their State and Tribal Implementation Plans (SIPs/TIPs).

  19. Toddler Nutrition: MedlinePlus Health Topic

    MedlinePlus

    ... in Spanish Healthy Eating for Preschoolers (Department of Agriculture) - PDF Also in Spanish Nutrition Guide for Toddlers ( ... 10 Tips for Setting Good Examples (Department of Agriculture) - PDF Also in Spanish Children's Nutrition: Tips for ...

  20. Vector vortex beam generation with dolphin-shaped cell meta-surface.

    PubMed

    Yang, Zhuo; Kuang, Deng-Feng; Cheng, Fang

    2017-09-18

    We present a dolphin-shaped cell meta-surface, which is a combination of dolphin-shaped metallic cells and dielectric substrate, for vector vortex beam generation with the illumination of linearly polarized light. Surface plasmon polaritons are excited at the boundary of the metallic cells, then guided by the metallic structures, and finally squeezed to the tips to form highly localized strong electromagnetic fields, which generate the intensity of vector vortex beams at z component. Synchronously, the abrupt phase change produced by the meta-surface is utilized to explain the vortex phase generated by elements. The new kind of structure can be utilized for communication, bioscience, and materiality.

  1. Novel cylindrical illuminator tip for ultraviolet light delivery

    NASA Astrophysics Data System (ADS)

    Shangguan, HanQun; Haw, Thomas E.; Gregory, Kenton W.; Casperson, Lee W.

    1993-06-01

    The design, processing, and sequential testing of a novel cylindrical diffusing optical fiber tip for ultraviolet light delivery is described. This device has been shown to uniformly (+/- 15%) illuminate angioplasty balloons, 20 mm in length, that are used in an experimental photochemotherapeutic treatment of swine intimal hyperplasia. Our experiments show that uniform diffusing tips of < 400 micron diameter can be reliably constructed for this and other interstitial applications. Modeling results indicate that this design is scalable to smaller diameters. The diffusing tips are made by stripping the protective buffer and etching away the cladding over a length of 20 mm from the fiber tip and replacing it with a thin layer of optical epoxy mixed with Al2O3 powder. To improve the uniformity and ease of fabrication, we have evaluated a new device configuration where the tip is etched into a modified conical shape, and the distal end face is polished and then coated with an optically opaque epoxy. This is shown to uniformly scatter approximately 70% of the light launched into the fiber without forward transmission.

  2. The PALM-3000 high-order adaptive optics system for Palomar Observatory

    NASA Astrophysics Data System (ADS)

    Bouchez, Antonin H.; Dekany, Richard G.; Angione, John R.; Baranec, Christoph; Britton, Matthew C.; Bui, Khanh; Burruss, Rick S.; Cromer, John L.; Guiwits, Stephen R.; Henning, John R.; Hickey, Jeff; McKenna, Daniel L.; Moore, Anna M.; Roberts, Jennifer E.; Trinh, Thang Q.; Troy, Mitchell; Truong, Tuan N.; Velur, Viswa

    2008-07-01

    Deployed as a multi-user shared facility on the 5.1 meter Hale Telescope at Palomar Observatory, the PALM-3000 highorder upgrade to the successful Palomar Adaptive Optics System will deliver extreme AO correction in the near-infrared, and diffraction-limited images down to visible wavelengths, using both natural and sodium laser guide stars. Wavefront control will be provided by two deformable mirrors, a 3368 active actuator woofer and 349 active actuator tweeter, controlled at up to 3 kHz using an innovative wavefront processor based on a cluster of 17 graphics processing units. A Shack-Hartmann wavefront sensor with selectable pupil sampling will provide high-order wavefront sensing, while an infrared tip/tilt sensor and visible truth wavefront sensor will provide low-order LGS control. Four back-end instruments are planned at first light: the PHARO near-infrared camera/spectrograph, the SWIFT visible light integral field spectrograph, Project 1640, a near-infrared coronagraphic integral field spectrograph, and 888Cam, a high-resolution visible light imager.

  3. Efficiency of light curing units in a government dental school.

    PubMed

    Nassar, Hani M; Ajaj, Reem; Hasanain, Fatin

    2018-01-01

    The light intensity of a light-curing unit is a crucial factor that affects the clinical longevity of resin composites. This study aimed to investigate the efficiency of light-curing units in use at a local governmental dental school for curing conventional and bulk-fill resin materials. A total of 166 light-curing units at three locations were examined, and the brand, type, clinic location, diameter of curing tip, tip cleanliness (using a visual score), and the output (in mW/cm 2 using a digital radiometer) were recorded. Only 23.5% of the units examined had clean tips, with the graduate student clinical area containing the highest percentage of clean tips. Further, tips with poor cleanliness score values were associated with significantly lower output intensities. A small percentage (9.4%) of units was capable of producing intensities higher than 1,200 mW/cm 2 and lower than 600 mW/cm 2 (7.6%). The majority of the low intensity units were located in the undergraduate student area, which also contained the highest number of units with intensities between 900 and 1,200 mW/cm 2 . The output of all the units in service was satisfactory for curing conventional resin composites, and most units were capable of curing bulk-fill resin materials.

  4. Blunt-tip coaxial introducer: a revisited tool for difficult CT-guided biopsy in the chest and abdomen.

    PubMed

    de Bazelaire, Cedric; Farges, Cecile; Mathieu, Olivier; Zagdanski, Anne-Marie; Bourrier, Pierre; Frija, Jacques; de Kerviler, Eric

    2009-08-01

    We describe a coaxial introducer provided with an additional blunt-tip stylet that allows safe access to difficult-to-reach lymph nodes in the chest, abdomen, and pelvis under CT control. Once the thoracic, abdominal, or pelvic wall is crossed by the introducer fitted with the sharp-tip stylet, the blunt-tip stylet replaces the sharp stylet for further progression in the fat toward the target. The soft-tip stylet carries a smaller risk of inadvertent perforation displacing vital structures.

  5. An optically coupled system for quantitative monitoring of MRI-induced RF currents into long conductors.

    PubMed

    Zanchi, Marta G; Venook, Ross; Pauly, John M; Scott, Greig C

    2010-01-01

    The currents induced in long conductors such as guidewires by the radio-frequency (RF) field in magnetic resonance imaging (MRI) are responsible for potentially dangerous heating of surrounding media, such as tissue. This paper presents an optically coupled system with the potential to quantitatively measure the RF currents induced on these conductors. The system uses a self shielded toroid transducer and active circuitry to modulate a high speed light-emitting-diode transmitter. Plastic fiber guides the light to a photodiode receiver and transimpedance amplifier. System validation included a series of experiments with bare wires that compared wire tip heating by fluoroptic thermometers with the RF current sensor response. Validations were performed on a custom whole body 64 MHz birdcage test platform and on a 1.5 T MRI scanner. With this system, a variety of phenomena were demonstrated including cable trap current attenuation, lossy dielectric Q-spoiling and even transverse electromagnetic wave node patterns. This system should find applications in studies of MRI RF safety for interventional devices such as pacemaker leads, and guidewires. In particular, variations of this device could potentially act as a realtime safety monitor during MRI guided interventions.

  6. Basic study of charring detection at the laser catheter-tip using back scattering light measurement during therapeutic laser irradiation in blood.

    PubMed

    Takahashi, Mei; Ito, Arisa; Kajihara, Takuro; Matsuo, Hiroki; Arai, Tsunenori

    2010-01-01

    The purpose of this study is to investigate transient process of the charring at the laser catheter-tip in blood during therapeutic laser irradiation by the back scattering light measurement to detect precursor state of the charring. We took account of using photodynamic therapy for arrhythmia in blood through the laser catheter. We observed the influence of the red laser irradiation (λ=663 nm) upon the shape of red blood cells (RBCs). The RBCs aggregation, round formation, and hemolysis were took place sequentially before charring. With a model blood sandwiched between glass plates simulated as a catheter-tip boundary, we measured diffuse-reflected-light power and transmitted-light power simultaneously and continuously by a microscopic optics during the laser irradiation. We found that measured light power changes were originated with RBCs shape change induced by temperature rise due to the laser irradiation. A gentle peak following a slow descending was observed in the diffuse-reflected-light power history. This history might indicate the precursor state of the charring, in which the hemolysis might be considered to advance rapidly. We think that the measurement of diffuse-reflected-light power history might be able to detect precursor state of charring at the catheter-tip in blood.

  7. Sports Nutrition.

    ERIC Educational Resources Information Center

    Missouri State Dept. of Health, Jefferson City.

    This guide deals with various aspects of sports and nutrition. Twelve chapters are included: (1) "Sports and Nutrition"; (2) "Eat to Compete"; (3) "Fit Folks Need Fit Food"; (4) "The Food Guide Pyramid"; (5) "Fat Finder's Guide"; (6) "Pre- and Post-Event Meals"; (7) "Tips for the…

  8. Water Worlds. 4-H Member's Guide M-5-18; 4-H Leaders Guide L-5-18.

    ERIC Educational Resources Information Center

    Hawkes, Janet E.; And Others

    This pocket folder of materials is designed to provide children aged 9 to 12 with an opportunity to explore and observe aquatic environments. The package includes a 4-H Leader's guide, member's guide, and supplementary materials. The leader's guide contains safety considerations, tips and techniques, and additional activities for getting started…

  9. The ARGOS laser system: green light for ground layer adaptive optics at the LBT

    NASA Astrophysics Data System (ADS)

    Raab, Walfried; Rabien, Sebastian; Gässler, Wolfgang; Esposito, Simone; Barl, Lothar; Borelli, Jose; Daysenroth, Matthias; Gemperlein, Hans; Kulas, Martin; Ziegleder, Julian

    2014-07-01

    We report on the development of the laser system of ARGOS, the multiple laser guide star adaptive optics system for the Large Binocular Telescope (LBT). The system uses a total of six high powered, pulsed Nd:YAG lasers frequency-doubled to a wavelength of 532 nm to generate a set of three guide stars above each of the LBT telescopes. The position of each of the LGS constellations on sky as well as the relative position of the individual laser guide stars within this constellation is controlled by a set of steerable mirrors and a fast tip-tilt mirror within the laser system. The entire opto-mechanical system is housed in two hermetically sealed and thermally controlled enclosures on the SX and DX side of the LBT telescope. The laser beams are propagated through two refractive launch telescopes which focus the beams at an altitude of 12 km, creating a constellation of laser guide stars around a 4 arcminute diameter circle by means of Rayleigh scattering. In addition to the GLAO Rayleigh beacon system, ARGOS has also been designed for a possible future upgrade with a hybrid sodium laser - Rayleigh beacon combination, enabling diffraction limited operation. The ARGOS laser system was successfully installed at the LBT in April 2013. Extensive functional tests have been carried out and have verified the operation of the systems according to specifications. The alignment of the laser system with respect to the launch telescope was carried out during two more runs in June and October 2013, followed by the first propagation of laser light on sky in November 2013.

  10. Mind the gap - tip leakage vortex in axial turbines

    NASA Astrophysics Data System (ADS)

    Dreyer, M.; Decaix, J.; Münch-Alligné, C.; Farhat, M.

    2014-03-01

    The tendency of designing large Kaplan turbines with a continuous increase of output power is bringing to the front the cavitation erosion issue. Due to the flow in the gap between the runner and the discharge ring, axial turbine blades may develop the so called tip leakage vortex (TLV) cavitation with negative consequences. Such vortices may interact strongly with the wake of guide vanes leading to their multiple collapses and rebounds. If the vortex trajectory remains close to the blade tip, these collapses may lead to severe erosion. One is still unable today to predict its occurrence and development in axial turbines with acceptable accuracy. Numerical flow simulations as well as the actual scale-up rules from small to large scales are unreliable. The present work addresses this problematic in a simplified case study representing TLV cavitation to better understand its sensitivity to the gap width. A Naca0009 hydrofoil is used as a generic blade in the test section of EPFL cavitation tunnel. A sliding mounting support allowing an adjustable gap between the blade tip and wall was manufactured. The vortex trajectory is visualized with a high speed camera and appropriate lighting. The three dimensional velocity field induced by the TLV is investigated using stereo particle image velocimetry. We have taken into account the vortex wandering in the image processing to obtain accurate measurements of the vortex properties. The measurements were performed in three planes located downstream of the hydrofoil for different values of the flow velocity, the incidence angle and the gap width. The results clearly reveal a strong influence of the gap width on both trajectory and intensity of the tip leakage vortex.

  11. Guidelines for development : Transportation Improvement Programs (TIPs) and the Iowa Statewide Transportation Improvement Program (STIP).

    DOT National Transportation Integrated Search

    2011-02-01

    This document serves as a reference guide to local planning agencies for the development of their regional Transportation Improvement Program (TIP) and the Statewide Transportation Improvement Program (STIP). Any questions regarding content or relati...

  12. Particle trapping in 3-D using a single fiber probe with an annular light distribution.

    PubMed

    Taylor, R; Hnatovsky, C

    2003-10-20

    A single optical fiber probe has been used to trap a solid 2 ìm diameter glass bead in 3-D in water. Optical confinement in 2-D was produced by the annular light distribution emerging from a selectively chemically etched, tapered, hollow tipped metalized fiber probe. Confinement of the bead in 3-D was achieved by balancing an electrostatic force of attraction towards the tip and the optical scattering force pushing the particle away from the tip.

  13. Laser ablated hard coating for microtools

    DOEpatents

    McLean, II, William; Balooch, Mehdi; Siekhaus, Wigbert J.

    1998-05-05

    Wear-resistant coatings composed of laser ablated hard carbon films, are deposited by pulsed laser ablation using visible light, on instruments such as microscope tips and micro-surgical tools. Hard carbon, known as diamond-like carbon (DLC), films produced by pulsed laser ablation using visible light enhances the abrasion resistance, wear characteristics, and lifetimes of small tools or instruments, such as small, sharp silicon tips used in atomic probe microscopy without significantly affecting the sharpness or size of these devices. For example, a 10-20 nm layer of diamond-like carbon on a standard silicon atomic force microscope (AFM) tip, enables the useful operating life of the tip to be increased by at least twofold. Moreover, the low inherent friction coefficient of the DLC coating leads to higher resolution for AFM tips operating in the contact mode.

  14. Bringing the sense back into healthy eating advice.

    PubMed

    Drummond, Sandra

    2006-01-01

    Conflicting messages about diet in the media, including publicity for "fad" diets, tend to distort the public's understanding of healthy eating. Several myths also persist, such as "skipping meals is a good way to lose weight," "all fats are bad" or "carbohydrates should be limited when trying to lose weight" Food labels, including the "traffic light" system, may also be confusing for some people. Food preferences vary between individuals, but health professionals can help guide individuals and towards a varied, balanced diet. This will include foods the individual and family enjoy, but based on appropriate proportions of all the five food groups, cooked in healthy ways. Some simple healthy eating tips are given to pass on to clients.

  15. EUS Needle Identification Comparison and Evaluation study (with videos).

    PubMed

    Tang, Shou-Jiang; Vilmann, Andreas S; Saftoiu, Adrian; Wang, Wanmei; Streba, Costin Teodor; Fink, Peter P; Griswold, Michael; Wu, Ruonan; Dietrich, Christoph F; Jenssen, Christian; Hocke, Michael; Kantowski, Marcus; Pohl, Jürgen; Fockens, Paul; Annema, Jouke T; van der Heijden, Erik H F M; Havre, Roald Flesland; Pham, Khanh Do-Cong; Kunda, Rastislav; Deprez, Pierre H; Mariana, Jinga; Vazquez-Sequeiros, Enrique; Larghi, Alberto; Buscarini, Elisabetta; Fusaroli, Pietro; Lahav, Maor; Puri, Rajesh; Garg, Pramod Kumar; Sharma, Malay; Maluf-Filho, Fauze; Sahai, Anand; Brugge, William R; Lee, Linda S; Aslanian, Harry R; Wang, Andrew Y; Shami, Vanessa M; Markowitz, Arnold; Siddiqui, Ali A; Mishra, Girish; Scheiman, James M; Isenberg, Gerard; Siddiqui, Uzma D; Shah, Raj J; Buxbaum, James; Watson, Rabindra R; Willingham, Field F; Bhutani, Manoop S; Levy, Michael J; Harris, Cynthia; Wallace, Michael B; Nolsøe, Christian Pállson; Lorentzen, Torben; Bang, Niels; Sørensen, Sten Mellerup; Gilja, Odd Helge; D'Onofrio, Mirko; Piscaglia, Fabio; Gritzmann, Norbert; Radzina, Maija; Sparchez, Zeno Adrian; Sidhu, Paul S; Freeman, Simon; McCowan, Timothy C; de Araujo, Cyrillo Rodrigues; Patel, Akash; Ali, Mohammad Adel; Campbell, Garth; Chen, Edward; Vilmann, Peter

    2016-09-01

    EUS-guided FNA or biopsy sampling is widely practiced. Optimal sonographic visualization of the needle is critical for image-guided interventions. Of the several commercially available needles, bench-top testing and direct comparison of these needles have not been done to reveal their inherent echogenicity. The aims are to provide bench-top data that can be used to guide clinical applications and to promote future device research and development. Descriptive bench-top testing and comparison of 8 commonly used EUS-FNA needles (all size 22 gauge): SonoTip Pro Control (Medi-Globe); Expect Slimline (Boston Scientific); EchoTip, EchoTip Ultra, EchoTip ProCore High Definition (Cook Medical); ClearView (Conmed); EZ Shot 2 (Olympus); and BNX (Beacon Endoscopic), and 2 new prototype needles, SonoCoat (Medi-Globe), coated by echogenic polymers made by Encapson. Blinded evaluation of standardized and unedited videos by 43 EUS endoscopists and 17 radiologists specialized in GI US examination who were unfamiliar with EUS needle devices. There was no significant difference in the ratings and rankings of these needles between endosonographers and radiologists. Overall, 1 prototype needle was rated as the best, ranking 10% to 40% higher than all other needles (P < .01). Among the commercially available needles, the EchoTip Ultra needle and the ClearView needle were top choices. The EZ Shot 2 needle was ranked statistically lower than other needles (30%-75% worse, P < .001). All FNA needles have their inherent and different echogenicities, and these differences are similarly recognized by EUS endoscopists and radiologists. Needles with polymeric coating from the entire shaft to the needle tip may offer better echogenicity. Copyright © 2016 American Society for Gastrointestinal Endoscopy. All rights reserved.

  16. New Technique for Fabrication of Scanning Single-Electron Transistor Microscopy Tips

    NASA Astrophysics Data System (ADS)

    Goodwin, Eric; Tessmer, Stuart

    Fabrication of glass tips for Scanning Single-Electron Transistor Microscopy (SSETM) can be expensive, time consuming, and inconsistent. Various techniques have been tried, with varying levels of success in regards to cost and reproducibility. The main requirement for SSETM tips is to have a sharp tip ending in a micron-scale flat face to allow for deposition of a quantum dot. Drawing inspiration from methods used to create tips from optical fibers for Near-Field Scanning Optical Microscopes, our group has come up with a quick and cost effective process for creating SSETM tips. By utilizing hydrofluoric acid to etch the tips and oleic acid to guide the etch profile, optical fiber tips with appropriate shaping can be rapidly prepared. Once etched, electric leads are thermally evaporated onto each side of the tip, while an aluminum quantum dot is evaporated onto the face. Preliminary results using various metals, oxide layers, and lead thicknesses have proven promising.

  17. Bullying 101: The Club Crew's Guide to Bullying Prevention

    ERIC Educational Resources Information Center

    PACER Center, 2013

    2013-01-01

    "Bullying 101" is the Club Crew's Guide to Bullying Prevention. A visually-friendly, age-appropriate, 16-page colorful guide for students to read or for parents to use when talking with children, this guide describes and explains what bullying is and is not, the roles of other students, and tips on what each student can do to prevent…

  18. Self-aligned grating couplers on template-stripped metal pyramids via nanostencil lithography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Klemme, Daniel J.; Johnson, Timothy W.; Mohr, Daniel A.

    2016-05-23

    We combine nanostencil lithography and template stripping to create self-aligned patterns about the apex of ultrasmooth metal pyramids with high throughput. Three-dimensional patterns such as spiral and asymmetric linear gratings, which can couple incident light into a hot spot at the tip, are presented as examples of this fabrication method. Computer simulations demonstrate that spiral and linear diffraction grating patterns are both effective at coupling light to the tip. The self-aligned stencil lithography technique can be useful for integrating plasmonic couplers with sharp metallic tips for applications such as near-field optical spectroscopy, tip-based optical trapping, plasmonic sensing, and heat-assisted magneticmore » recording.« less

  19. Turbine nozzle positioning system

    DOEpatents

    Norton, Paul F.; Shaffer, James E.

    1996-01-30

    A nozzle guide vane assembly having a preestablished rate of thermal expansion is positioned in a gas turbine engine and being attached to conventional metallic components. The nozzle guide vane assembly includes an outer shroud having a mounting leg with an opening defined therein, a tip shoe ring having a mounting member with an opening defined therein, a nozzle support ring having a plurality of holes therein and a pin positioned in the corresponding opening in the outer shroud, opening in the tip shoe ring and the hole in the nozzle support ring. A rolling joint is provided between metallic components of the gas turbine engine and the nozzle guide vane assembly. The nozzle guide vane assembly is positioned radially about a central axis of the gas turbine engine and axially aligned with a combustor of the gas turbine engine.

  20. Turbine nozzle positioning system

    DOEpatents

    Norton, P.F.; Shaffer, J.E.

    1996-01-30

    A nozzle guide vane assembly having a preestablished rate of thermal expansion is positioned in a gas turbine engine and being attached to conventional metallic components. The nozzle guide vane assembly includes an outer shroud having a mounting leg with an opening defined therein, a tip shoe ring having a mounting member with an opening defined therein, a nozzle support ring having a plurality of holes therein and a pin positioned in the corresponding opening in the outer shroud, opening in the tip shoe ring and the hole in the nozzle support ring. A rolling joint is provided between metallic components of the gas turbine engine and the nozzle guide vane assembly. The nozzle guide vane assembly is positioned radially about a central axis of the gas turbine engine and axially aligned with a combustor of the gas turbine engine. 9 figs.

  1. Integrated fiber optic light probe: Measurement of static deflections in rotating turbomachinery

    NASA Astrophysics Data System (ADS)

    Dhadwal, Harbans S.; Mehmud, Ali; Khan, Romel; Kurkov, Anatole

    1996-02-01

    This paper describes the design, fabrication, and testing of an integrated fiber optic light probe system for monitoring blade tip deflections, vibrational modes, and changes in blade tip clearances in the compressor stage of rotating turbomachinery. The system comprises a set of integrated fiber optic light probes which are positioned to detect the passing blade tip at the leading and the trailing edges. In this configuration measurements of both blade vibrations and steady-state blade deflection can be obtained from the timing information provided by each light probe, which comprises an integrated fiber optic transmitting channel and a number of high numerical aperture receiving fibers, all mounted in the same cylindrical housing. A spatial resolution of 50 μm is possible with the integrated fiber optic technology, while keeping the outer diameter below 2.5 mm. Additionally, one fiber sensor provides a capability of monitoring changes in the blade tip clearance of the order of 10 μm. Measurements from a single stage compressor facility and an engine-fan rig in a 9 ft×15 ft subsonic wind tunnel are presented.

  2. Closed retrograde retrieval of the distal broken segment of femoral cannulated intramedullary nail using a ball-tipped guide wire.

    PubMed

    Metikala, Sreenivasulu; Mohammed, Riazuddin

    2011-07-01

    Extracting broken segments of intramedullay nails from long bones can be an operative challenge, particularly from the distal end. We report a case series where a simple and reproducible technique of extracting broken femoral cannulated nails using a ball-tipped guide wire is described. This closed technique involves no additional equipment or instruments. Eight patients who underwent the described method were included in the study. The technique involves using a standard plain guide wire passed through the cannulated distal broken nail segment after extraction of the proximal nail fragment. The plain guide wire is then advanced distally into the knee joint carefully under fluoroscopy imaging. Over this wire, a 5-millimeter (mm) cannulated large drill bit is used to create a track up to the distal broken nail segment. Through the small knee wound, a ball-tipped guide wire is passed, smooth end first, till the ball engages the end of the nail. The guide wire is then extracted along with the broken nail through the proximal wound. The method was successfully used in all eight patients for removal of broken cannulated intramedullary nail from the femoral canal without any complications. All patients underwent exchange nailing with successful bone union in six months. None of the patients had any problems at the knee joint at the final follow-up. We report a technique for successful extraction of the distal fragment of broken femoral intramedullary nails without additional surgical approaches.

  3. TAKING IT TO THE PEWS: A CBPR-GUIDED HIV AWARENESS AND SCREENING PROJECT WITH BLACK CHURCHES

    PubMed Central

    Berkley-Patton, Jannette; Bowe-Thompson, Carole; Bradley-Ewing, Andrea; Hawes, Starlyn; Moore, Erin; Williams, Eric; Martinez, David; Goggin, Kathy

    2014-01-01

    Utilizing a community-based participatory research (CBPR) approach is a potentially effective strategy for exploring the development, implementation, and evaluation of HIV interventions in African American churches. This CBPR-guided study describes a church-based HIV awareness and screening intervention (Taking It to the Pews [TIPS]) that fully involved African American church leaders in all phases of the research project. Findings from the implementation and evaluation phases indicated that church leaders delivered TIPS Tool Kit activities on an ongoing basis (about twice a month) over a 9-month period. TIPS church members were highly exposed to TIPS activities (e.g., 91% reported receiving HIV educational brochures, 84% heard a sermon about HIV). Most (87%) believed that the church should talk about HIV, and 77% believed that the church should offer HIV screening. These findings suggest that implementing an HIV intervention in Black church settings is achievable, particularly when a CBPR approach is used. PMID:20528130

  4. Laser ablated hard coating for microtools

    DOEpatents

    McLean, W. II; Balooch, M.; Siekhaus, W.J.

    1998-05-05

    Wear-resistant coatings composed of laser ablated hard carbon films, are deposited by pulsed laser ablation using visible light, on instruments such as microscope tips and micro-surgical tools. Hard carbon, known as diamond-like carbon (DLC), films produced by pulsed laser ablation using visible light enhances the abrasion resistance, wear characteristics, and lifetimes of small tools or instruments, such as small, sharp silicon tips used in atomic probe microscopy without significantly affecting the sharpness or size of these devices. For example, a 10--20 nm layer of diamond-like carbon on a standard silicon atomic force microscope (AFM) tip, enables the useful operating life of the tip to be increased by at least twofold. Moreover, the low inherent friction coefficient of the DLC coating leads to higher resolution for AFM tips operating in the contact mode. 12 figs.

  5. In vitro assessment of polymerization procedures in Class II restorations: sealing, FTIR, and microhardness evaluations.

    PubMed

    Tassery, H; de Donato, P; Barrès, O; Déjou, J

    2001-01-01

    This study was undertaken to evaluate several polymerization and filling procedures (incremental, bulk, light-tip, soft-cured, plasma devices) in Class II restorations through (1) a sealing evaluation of restorations filled with Tetric Ceram (TC) and Bisfil 2B (B2B, self-cured composite used as a control), (2) a FTIR analysis measuring the variations of the degree of conversion in terms of area unit ratio of the relevant resin composites and (3) a microhardness test to corroborate the FTIR analysis. The length of the tracer penetration was measured from the gingival margin up to the cavity wall with an episcope on sectioned teeth. A ceramic mould, simulating a Class II, was filled according to the different groups and the samples were analyzed with a Bruker IFS 55 spectrometer on ultrathin sections (3 mu). The results were analyzed in terms of area unit ratio and total exposed energy. Under the same conditions, a microhardness test was run with a Frank Weihem machine. The results of the sealing evaluation for light-tip, incremental and self-cured techniques did not differ. The plasma procedure failed in this evaluation as the bottom increment was not polymerized. The smallest area unit ratio (the best degree of conversion) was observed in 2 groups: one, the combination of the light-tip and soft process, and two, the self-cured resin composite (B2B). The distance at which the plasma procedure failed to cure the resin composite was between 3.5 and 4.5 mm. The microhardness test confirmed the FTIR analysis except for the group G2 (TC + light-tip). As also shown by FTIR analysis, no difference between the two relevant levels was observed with the hardness test. The dentin marginal sealing efficiency of Tetric Ceram restorations was increased with the light-tip technique, but was not better than the self-cured resin composite (B2B). For Tetric Ceram, the combination of the light-tip and soft process leads to a higher degree of conversion than the other groups. There is no linear relationship between the degree of conversion, the microhardness and the total exposed energy. The combination of the soft polymerization and the light-tip device might be an alternative restorative technique to the current incremental technique.

  6. On-sky performance of the tip-tilt correction system for GLAS using an EMCCD camera

    NASA Astrophysics Data System (ADS)

    Skvarč, Jure; Tulloch, Simon

    2008-07-01

    Adaptive optics systems based on laser guide stars still need a natural guide star (NGS) to correct for the image motion caused by the atmosphere and by imperfect telescope tracking. The ability to properly compensate for this motion using a faint NGS is critical to achieve large sky coverage. For the laser guide system (GLAS) on the 4.2 m William Herschel Telescope we designed and tested in the laboratory and on-sky a tip-tilt correction system based on a PC running Linux and an EMCCD technology camera. The control software allows selection of different centroiding algorithms and loop control methods as well as the control parameters. Parameter analysis has been performed using tip-tilt only correction before the laser commissioning and the selected sets of parameters were then used during commissioning of the laser guide star system. We have established the SNR of the guide star as a function of magnitude, depending on the image sampling frequency and on the dichroic used in the optical system; achieving a measurable improvement using full AO correction with NGSes down to magnitude range R=16.5 to R=18. A minimum SNR of about 10 was established to be necessary for a useful correction. The system was used to produce 0.16 arcsecond images in H band using bright NGS and laser correction during GLAS commissioning runs.

  7. Colorado Fathers' Resource Guide = Guia de Recursos para los Padres en Colorado.

    ERIC Educational Resources Information Center

    Colorado Foundation for Families and Children, Denver.

    Developed through the Colorado Fatherhood Connection, this guide, in English- and Spanish-language versions, provides suggestions and resources for fathers as well as tips on discipline, communication, and activities fathers can do with their children. Topics addressed in the guide include characteristics of responsible fatherhood, characteristics…

  8. Low-coherence interferometric tip-clearance probe

    NASA Astrophysics Data System (ADS)

    Kempe, Andreas; Schlamp, Stefan; Rösgen, Thomas; Haffner, Ken

    2003-08-01

    We propose an all-fiber, self-calibrating, economical probe that is capable of near-real-time, single-port, simultaneous blade-to-blade tip-clearance measurements with submillimeter accuracy (typically <100 μm, absolute) in the first stages of a gas turbine. Our probe relies on the interference between backreflected light from the blade tips during the 1-μs blade passage time and a frequency-shifted reference with variable time delay, making use of a low-coherence light source. A single optical fiber of arbitrary length connects the self-contained optics and electronics to the turbine.

  9. Positive and negative tropic curvature induced by microbeam irradiation of protonemal tip cells of the moss Ceratodon purpureus.

    PubMed

    Lamparter, T; Kagawa, T; Brücker, G; Wada, M

    2004-01-01

    The photoreceptor phytochrome mediates tropic responses in protonemata of the moss Ceratodon purpureus. Under standard conditions the tip cells grow towards unilateral red light, or perpendicular to the electrical vector of polarized light. In this study the response of tip cells to partial irradiation of the apical region was analysed using a microbeam apparatus. The fluence response curve gave an unexpected pattern: whereas a 15-min microbeam with light intensities around 3 micro mol m (-2) s (-1) induced a growth curvature towards the irradiated side, higher light intensities around 100 micro mol m (-2) s (-1) caused a negative response, the cells grew away from the irradiated side. This avoidance response is explained by two effects: the light intensity is high enough to induce photoconversion into the active Pfr form of phytochrome, not only on the irradiated but also on the non-irradiated side by stray light. At the same time, the strong light on the irradiated side acts antagonistically to Pfr. As a result of this inhibition, the growth direction is moved to the light-avoiding side. Such a Pfr-independent mechanism might be important for the phototropic response to distinguish between the light-directed and light-avoiding side under unilateral light.

  10. Doppler-guided retrograde catheterization system

    NASA Astrophysics Data System (ADS)

    Frazin, Leon J.; Vonesh, Michael J.; Chandran, Krishnan B.; Khasho, Fouad; Lanza, George M.; Talano, James V.; McPherson, David D.

    1991-05-01

    The purpose of this study was to investigate a Doppler guided catheterization system as an adjunctive or alternative methodology to overcome the disadvantages of left heart catheterization and angiography. These disadvantages include the biological effects of radiation and the toxic and volume effects of iodine contrast. Doppler retrograde guidance uses a 20 MHz circular pulsed Doppler crystal incorporated into the tip of a triple lumen multipurpose catheter and is advanced retrogradely using the directional flow information provided by the Doppler waveform. The velocity detection limits are either 1 m/second or 4 m/second depending upon the instrumentation. In a physiologic flow model of the human aortic arch, multiple data points revealed a positive wave form when flow was traveling toward the catheter tip indicating proper alignment for retrograde advancement. There was a negative wave form when flow was traveling away from the catheter tip if the catheter was in a branch or bent upon itself indicating improper catheter tip position for retrograde advancement. In a series of six dogs, the catheter was able to be accurately advanced from the femoral artery to the left ventricular chamber under Doppler signal guidance without the use of x-ray. The potential applications of a Doppler guided retrograde catheterization system include decreasing time requirements and allowing safer catheter guidance in patients with atherosclerotic vascular disease and suspected aortic dissection. The Doppler system may allow left ventricular pressure monitoring in the intensive care unit without the need for x-ray and it may allow left sided contrast echocardiography. With pulse velocity detection limits of 4 m/second, this system may allow catheter direction and passage into the aortic root and left ventricle in patients with aortic stenosis. A modification of the Doppler catheter may include transponder technology which would allow precise catheter tip localization once the catheter tip is placed in the aortic root. Such technology may conceivably assist in allowing selective coronary catheterization. These studies have demonstrated that Doppler guided retrograde catheterization provides an accurate method to catheterization the aortic root and left ventricular chamber without x-ray. In humans, it may prove useful in a variety of settings including the development of invasive ultrasonic diagnostic and therapeutic technology.

  11. Intravascular US-Guided Portal Vein Access: Improved Procedural Metrics during TIPS Creation.

    PubMed

    Gipson, Matthew G; Smith, Mitchell T; Durham, Janette D; Brown, Anthony; Johnson, Thor; Ray, Charles E; Gupta, Rajan K; Kondo, Kimi L; Rochon, Paul J; Ryu, Robert K

    2016-08-01

    To evaluate transjugular intrahepatic portosystemic shunt (TIPS) outcomes and procedure metrics with the use of three different image guidance techniques for portal vein (PV) access during TIPS creation. A retrospective review of consecutive patients who underwent TIPS procedures for a range of indications during a 28-month study period identified a population of 68 patients. This was stratified by PV access techniques: fluoroscopic guidance with or without portography (n = 26), PV marker wire guidance (n = 18), or intravascular ultrasound (US) guidance (n = 24). Procedural outcomes and procedural metrics, including radiation exposure, contrast agent volume used, procedure duration, and PV access time, were analyzed. No differences in demographic or procedural characteristics were found among the three groups. Technical success, technical success of the primary planned approach, hemodynamic success, portosystemic gradient, and procedure-related complications were not significantly different among groups. Fluoroscopy time (P = .003), air kerma (P = .01), contrast agent volume (P = .003), and total procedural time (P = .02) were reduced with intravascular US guidance compared with fluoroscopic guidance. Fluoroscopy time (P = .01) and contrast agent volume (P = .02) were reduced with intravascular US guidance compared with marker wire guidance. Intravascular US guidance of PV access during TIPS creation not only facilitates successful TIPS creation in patients with challenging anatomy, as suggested by previous investigations, but also reduces important procedure metrics including radiation exposure, contrast agent volume, and overall procedure duration compared with fluoroscopically guided TIPS creation. Copyright © 2016 SIR. Published by Elsevier Inc. All rights reserved.

  12. Aquatics. NAGWS Guide. July 1979-July 1981. Tips and Techniques for Teachers and Coaches.

    ERIC Educational Resources Information Center

    Polvino, Geri, Ed.; And Others

    Articles covering a wide spectrum of aquatic sports are presented as aids to teachers and coaches of swimming. Included are suggestions for teaching swimming to the handicapped and infants, specific techniques for developing swimming skills, and tips for boating education and water safety. (JD)

  13. Darkfield microspectroscopy of nanostructures on silver tip-enhanced Raman scattering probes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Itoh, Tamitake, E-mail: tamitake-itou@aist.go.jp; Yamamoto, Yuko S., E-mail: yamayulab@gmail.com; Department of Chemistry, School of Science and Technology, Kagawa University, Takamatsu, Kagawa 761-0396

    2016-01-11

    We report an evaluation method employing darkfield microspectroscopy for silver probes used in tip-enhanced Raman scattering (TERS). By adjusting the darkfield illumination, the diffracted light from the probe outlines disappears and the diffracted light from the surface nanostructures and tips of the probes appears as colorful spots. Scanning electron microscopy reveals that the spectral variations in these spots reflect the shapes of the surface nanostructures. The tip curvatures correlate to the spectral maxima of their spots. Temporal color changes in the spots indicate the deterioration due to the oxidation of the silver surfaces. These results show that the proposed methodmore » is useful for in situ evaluation of plasmonic properties of TERS probes.« less

  14. Needle tip visualization by bevel-point ultrasound generator and prototype photoacoustic imaging system

    NASA Astrophysics Data System (ADS)

    Irisawa, Kaku; Murakoshi, Dai; Hashimoto, Atsushi; Yamamoto, Katsuya; Hayakawa, Toshiro

    2017-03-01

    Visualization of the tip of medical devices like needles or catheters under ultrasound imaging has been a continuous topic since the early 1980's. In this study, a needle tip visualization system utilizing photoacoustic effects is proposed. In order to visualize the needle tip, an optical fiber was inserted into a needle. The optical fiber tip is placed on the needle bevel and affixed with black glue. The pulsed laser light from laser diode was transferred to the optical fiber and converted to ultrasound due to laser light absorption of the black glue and the subsequent photoacoustic effect. The ultrasound is detected by transducer array and reconstructed into photoacoustic images in the ultrasound unit. The photoacoustic image is displayed with a superposed ultrasound B-mode image. As a system evaluation, the needle is punctured into bovine meat and the needle tip is observed with commercialized conventional linear transducers or convex transducers. The needle tip is visualized clearly at 7 and 12 cm depths with linear and convex probes, respectively, even with a steep needle puncture angle of around 90 degrees. Laser and acoustic outputs, and thermal rise at the needle tip, were measured and were well below the limits of the safety standards. Compared with existing needle tip visualization technologies, the photoacoustic needle tip visualization system has potential distinguishable features for clinical procedures related with needle puncture and injection.

  15. Medical catheters thermally manipulated by fiber optic bundles

    DOEpatents

    Chastagner, Philippe

    1992-01-01

    A maneuverable medical catheter comprising a flexible tube having a functional tip. The catheter is connected to a control source. The functional tip of the catheter carries a plurality of temperature activated elements arranged in parallel and disposed about the functional tip and held in spaced relation at each end. These elements expand when they are heated. A plurality of fiber optic bundles, each bundle having a proximal end attached to the control source and a distal end attached to one of the elements carry light into the elements where the light is absorbed as heat. By varying the optic fiber that is carrying the light and the intensity of the light, the bending of the elements can be controlled and thus the catheter steered. In an alternate embodiment, the catheter carries a medical instrument for gathering a sample of tissue. The instrument may also be deployed and operated by thermal expansion and contraction of its moving parts.

  16. ARGOS wavefront sensing: from detection to correction

    NASA Astrophysics Data System (ADS)

    Orban de Xivry, Gilles; Bonaglia, M.; Borelli, J.; Busoni, L.; Connot, C.; Esposito, S.; Gaessler, W.; Kulas, M.; Mazzoni, T.; Puglisi, A.; Rabien, S.; Storm, J.; Ziegleder, J.

    2014-08-01

    Argos is the ground-layer adaptive optics system for the Large Binocular Telescope. In order to perform its wide-field correction, Argos uses three laser guide stars which sample the atmospheric turbulence. To perform the correction, Argos has at disposal three different wavefront sensing measurements : its three laser guide stars, a NGS tip-tilt, and a third wavefront sensor. We present the wavefront sensing architecture and its individual components, in particular: the finalized Argos pnCCD camera detecting the 3 laser guide stars at 1kHz, high quantum efficiency and 4e- noise; the Argos tip-tilt sensor based on a quad-cell avalanche photo-diodes; and the Argos wavefront computer. Being in the middle of the commissioning, we present the first wavefront sensing configurations and operations performed at LBT, and discuss further improvements in the measurements of the 3 laser guide star slopes as detected by the pnCCD.

  17. Inside KidVid: The Essential Parents' Guide to Video.

    ERIC Educational Resources Information Center

    MacAlpine, Loretta

    This guide aims to help parents choose stimulating, educational, and fun videos for their children from the more than 7,000 currently available. The guide includes: 10 tips for evaluating and choosing videos; interviews with and advice from experts; annotated descriptions of more than 400 recommended videos; essential information such as suggested…

  18. Tips for Finding the Right Partner. A TASC Resource Guide

    ERIC Educational Resources Information Center

    ExpandED Schools, 2014

    2014-01-01

    ExpandED Schools (formerly TASC) has spent the past 17 years helping schools and community organizations find the right partners. This resource guide offers a guide to the strategic questions school teams might ask themselves and their potential partners to have the best outcomes for young people. The following attachment is included: School…

  19. Micromilled optical elements for edge-lit illumination panels

    NASA Astrophysics Data System (ADS)

    Ronny, Rahima Afrose; Knopf, George K.; Bordatchev, Evgueni; Nikumb, Suwas

    2013-04-01

    Edge-lit light guide panels (LGPs) with micropatterned surfaces represent a new technology for developing small- and medium-sized illumination sources for application such as automotive, residential lighting, and advertising displays. The shape, density, and spatial distribution of the micro-optical structures (MOSs) imprinted on the transparent LGP must be selected to achieve high brightness and uniform luminance over the active surface. We examine how round-tip cylindrical MOSs fabricated by precision micromilling can be used to create patterned surfaces on low-cost transparent polymethyl-methacrylate substrates for high-intensity illumination applications. The impact of varying the number, pitch, spatial distribution, and depth of the optical microstructures on lighting performance is initially investigated using LightTools™ simulation software. To illustrate the microfabrication process, several 100×100×6 mm3 LGP prototypes are constructed and tested. The prototypes include an "optimized" array of MOSs that exhibit near-uniform illumination (approximately 89%) across its active light-emitting surface. Although the average illumination was 7.3% less than the value predicted from numerical simulation, it demonstrates how LGPs can be created using micromilling operations. Customized MOS arrays with a bright rectangular pattern near the center of the panel and a sequence of MOSs that illuminate a predefined logo are also presented.

  20. A novel carbon tipped single micro-optrode for combined optogenetics and electrophysiology

    PubMed Central

    Vizvári, Attila D.; Bali, Zsolt K.; Márki, Balázs; Nagy, Lili V.; Kónya, Zoltán; Madarász, Dániel; Henn-Mike, Nóra; Varga, Csaba; Hernádi, István

    2018-01-01

    Optical microelectrodes (optrodes) are used in neuroscience to transmit light into the brain of a genetically modified animal to evoke and record electrical activity from light-sensitive neurons. Our novel micro-optrode solution integrates a light-transmitting 125 micrometer optical fiber and a 9 micrometer carbon monofilament to form an electrical lead element, which is contained in a borosilicate glass sheathing coaxial arrangement ending with a micrometer-sized carbon tip. This novel unit design is stiff and slender enough to be used for targeting deep brain areas, and may cause less tissue damage compared with previous models. The center-positioned carbon fiber is less prone to light-induced artifacts than side-lit metal microelectrodes previously presented. The carbon tip is capable of not only recording electrical signals of neuronal origin but can also provide valuable surface area for electron transfer, which is essential in electrochemical (voltammetry, amperometry) or microbiosensor applications. We present details of design and manufacture as well as operational examples of the newly developed single micro-optrode, which includes assessments of 1) carbon tip length–impedance relationship, 2) light transmission capabilities, 3) photoelectric artifacts in carbon fibers, 4) responses to dopamine using fast-scan cyclic voltammetry in vivo, and 5) optogenetic stimulation and spike or local field potential recording from the rat brain transfected with channelrhodopsin-2. With this work, we demonstrate that our novel carbon tipped single micro-optrode may open up new avenues for use in optogenetic stimulation when needing to be combined with extracellular recording, electrochemical, or microbiosensor measurements performed on a millisecond basis. PMID:29513711

  1. Detecting and Segregating Black Tip-Damaged Wheat Kernels Using Visible and Near Infrared Spectroscopy

    USDA-ARS?s Scientific Manuscript database

    Detection of individual wheat kernels with black tip symptom (BTS) and black tip damage (BTD) was demonstrated using near infrared reflectance spectroscopy (NIRS) and silicon light-emitting-diode (LED) based instruments. The two instruments tested, a single kernel near-infrared spectroscopy instrume...

  2. Theoretical analysis of bimetallic nanorod dimer biosensors for label-free molecule detection

    NASA Astrophysics Data System (ADS)

    Das, Avijit; Talukder, Muhammad Anisuzzaman

    2018-02-01

    In this work, we theoretically analyze a gold (Au) core within silver (Ag) shell (Au@Ag) nanorod dimer biosensor for label-free molecule detection. The incident light on an Au@Ag nanorod strongly couples to localized surface plasmon modes, especially around the tip region. The field enhancement around the tip of a nanorod or between the tips of two longitudinally aligned nanorods as in a dimer can be exploited for sensitive detection of biomolecules. We derive analytical expressions for the interactions of an Au@Ag nanorod dimer with the incident light. We also study the detail dynamics of an Au@Ag nanorod dimer with the incident light computationally using finite difference time domain (FDTD) technique when core-shell ratio, relative position of the nanorods, and angle of incidence of light change. We find that the results obtained using the developed analytical model match well with that obtained using FDTD simulations. Additionally, we investigate the sensitivity of the Au@Ag nanorod dimer, i.e., shift in the resonance wavelength, when a target biomolecule such as lysozyme (Lys), human serum albumin (HSA), anti-biotin (Abn), human catalase (CAT), and human fibrinogen (Fb) protein molecules are attached to the tips of the nanorods.

  3. Energy Savers: Tips on Saving Money & Energy at Home

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    Provides consumers with home energy and money savings tips such as insulation, weatherization, heating, cooling, water heating, energy efficient windows, landscaping, lighting, and energy efficient appliances.

  4. Energy Saver: Tips on Saving Money & Energy at Home

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    Provides consumers with home energy and money savings tips such as insulation, weatherization, heating, cooling, water heating, energy efficient windows, landscaping, lighting, and energy efficient appliances.

  5. Internal Acoustics Measurements of a Full Scale Advanced Ducted Propulsor Demonstrator

    NASA Technical Reports Server (NTRS)

    Santa Maria, O. L.; Soderman, P. T.; Horne, W. C.; Jones, M. G.; Bock, L. A.

    1995-01-01

    Acoustics measurements of a Pratt & Whitney full-scale ADP (Advanced Ducted Propulsor), an ultrahigh by-pass ratio engine, were conducted in the NASA Ames 40- by 80-Foot Wind Tunnel. This paper presents data from measurements taken from sensors on a fan exit guide vane in the ADP. Data from two sensors, one at mid-span and the other at the tip of the fan exit guide vane, are presented. At the blade passage frequency (BPF), the levels observed at the various engine and wind speeds were higher at the mid-span sensor than the tip sensor. The coherence between these internal sensors and external microphones were calculated and plotted as a function of angle (angles ranged from 5 degrees to 160 degrees) relative to the ADP longitudinal axis. At the highest engine and wind speeds, the coherence between the tip sensor and the external microphones was observed to decrease at higher multiples of the BPF. These results suggest that the rotor-stator interaction tones are stronger in the mid-span region than at the tip.

  6. Characterization and Modeling of Nano-organic Thin Film Phototransistors Based on 6,13(Triisopropylsilylethynyl)-Pentacene: Photovoltaic Effect

    NASA Astrophysics Data System (ADS)

    Jouili, A.; Mansouri, S.; Al-Ghamdi, Ahmed A.; El Mir, L.; Farooq, W. A.; Yakuphanoglu, F.

    2017-04-01

    Organic thin film transistors based on 6,13(triisopropylsilylethynyl)-pentacene (TIPS-pentacene) with various channel widths and thicknesses of the active layer (300 nm and 135 nm) were photo-characterized. The photoresponse behavior and the gate field dependence of the charge transport were analyzed in detail. The surface properties of TIPS-pentacene deposited on silicon dioxide substrate were investigated using an atomic force microscope. We confirm that the threshold voltage values of the TIPS-pentacene transistor depend on the intensity of white light illumination. With the multiple trapping and release model, we have developed an analytical model that was applied to reproduce the experimental output characteristics of organic thin film transistors based on TIPS-pentacene under dark and under light illumination.

  7. Excitation of surface plasmons in Al-coated SNOM tips

    NASA Astrophysics Data System (ADS)

    Palm, Viktor; Rähn, Mihkel; Jäme, Joonas; Hizhnyakov, Vladimir

    2012-10-01

    The mesoscopic effect of spectral modulation occurring due to the interference of two photonic fiber modes filtered out by a metal-coated SNOM tip is used to observe the surface plasmon polariton (SPP) excitation in SNOM tips. In a spectrum of the broadband light transmitted by a SNOM tip a region of highly regular spectral modulation can be found, indicating the spectral interval in which only two photonic modes (apparently HE11 and TM01) are transmitted with significant and comparable amplitudes. The modulation period yields the value of optical path difference (OPD) for this pair of modes. Due to the multimode fiber's inherent modal dispersion, this OPD value depends linearly on the fiber tail length l. An additional contribution to OPD can be generated in a metal-coated SNOM tip due to a mode-dependent photon-plasmon coupling strength resulting in generation of SPPs with different propagation velocities. For an Al-coated 200 nm SNOM tip spectra of transmitted light have been registered for ten different l values. An extrapolation of the linear OPD (l) dependence to l=0 yields a significant residual OPD value, indicating according to our theoretical considerations a mode-selective SPP excitation in the metal-coated tip. The modal dispersion is shown to switch its sign in the SNOM tip. First results of analogous experiments with an Al-coated 150 nm SNOM tip confirm our conclusions.

  8. Dave Sperling's Guide to the Internet's Best Writing Resources.

    ERIC Educational Resources Information Center

    Sperling, Dave

    2003-01-01

    Provides a guide to writing resources on the Internet, including resources for business writing, dictionaries and thesauruses, e-mail, encyclopedias, free Web space, grammar, fun, online help, online writing labs, punctuation, and spelling. Lists useful Internet tips. (Author/VWL)

  9. Troubleshooting Microcomputers. A Technical Guide for Polk County Schools.

    ERIC Educational Resources Information Center

    Black, B. R.; And Others

    This guide was started in 1986 as an effort to pull together a collection of several computer guides that had been written over the previous several years to assist schools in making simple computer repairs. The first of six sections contains general tips and hints, including sections on tool requirements, strobe disk speed adjustment, static…

  10. Building Villages To Raise Our Children: Funding and Resources. Guides to Comprehensive Family Support Services.

    ERIC Educational Resources Information Center

    Fay, Juliette; And Others

    This guide, Part 2 of a 6-volume guide, is designed to assist program managers in maintaining comprehensive family-support programs through creative funding. It stresses building a portfolio of resources to serve the families within the communities. It also examines the general principles of financing strategy, potential funding sources, tips on…

  11. Textile Science Leader's Guide. 4-H Textile Science.

    ERIC Educational Resources Information Center

    Scholl, Jan

    This instructor's guide provides an overview of 4-H student project modules in the textile sciences area. The guide includes short notes explaining how to use the project modules, a flowchart chart showing how the project areas are sequenced, a synopsis of the design and content of the modules, and some program planning tips. For each of the…

  12. Targeted Management Tips to Enhance the Effectiveness of Tier 2, Guided Reading Instruction

    ERIC Educational Resources Information Center

    Marchand-Martella, Nancy E.; Martella, Ronald C.; Lambert, M. Charles

    2015-01-01

    Guided reading is a popular approach to teaching reading in today's schools. With the increase of schools and districts implementing response-to-intervention programs, guided reading can be easily enhanced to provide additional supports for students at risk for school failure who exhibit learning and behavioral challenges. This column offers…

  13. Needle localization using a moving stylet/catheter in ultrasound-guided regional anesthesia: a feasibility study

    NASA Astrophysics Data System (ADS)

    Beigi, Parmida; Rohling, Robert

    2014-03-01

    Despite the wide range and long history of ultrasound guided needle insertions, an unresolved issue in many cases is clear needle visibility. A well-known ad hoc technique to detect the needle is to move the stylet and look for changes in the needle appearance. We present a new method to automatically locate a moving stylet/catheter within a stationary cannula using motion detection. We then use this information to detect the needle trajectory and the tip. The differences between the current frame and the previous frame are detected and localized, to minimize the influence of tissue global motions. A polynomial fit based on the detected needle axis determines the estimated stylet shaft trajectory, and the extent of the differences along the needle axis represents the tip. Over a few periodic movements of the stylet including its full insertion into the cannula to the tip, a combination of polynomial fits determines the needle trajectory and the last detected point represents the needle tip. Experiments are conducted in water bath and bovine muscle tissue for several stylet/catheter materials. Results show that a plastic stylet has the best needle shaft and tip localization accuracy in the water bath with RMSE = 0:16 mm and RMSE = 0:51 mm, respectively. In the bovine tissue, the needle tip was best localized with the plastic catheter with RMSE = 0:33 mm. The stylet tip localization was most accurate with the steel stylet, with RMSE = 2:81 mm and the shaft was best localized with the plastic catheter, with RMSE = 0:32 mm.

  14. Mass spectrometry analysis and transcriptome sequencing reveal glowing squid crystal proteins are in the same superfamily as firefly luciferase

    PubMed Central

    Gimenez, Gregory; Metcalf, Peter; Paterson, Neil G.; Sharpe, Miriam L.

    2016-01-01

    The Japanese firefly squid Hotaru-ika (Watasenia scintillans) produces intense blue light from photophores at the tips of two arms. These photophores are densely packed with protein microcrystals that catalyse the bioluminescent reaction using ATP and the substrate coelenterazine disulfate. The squid is the only organism known to produce light using protein crystals. We extracted microcrystals from arm tip photophores and identified the constituent proteins using mass spectrometry and transcriptome libraries prepared from arm tip tissue. The crystals contain three proteins, wsluc1–3, all members of the ANL superfamily of adenylating enzymes. They share 19 to 21% sequence identity with firefly luciferases, which produce light using ATP and the unrelated firefly luciferin substrate. We propose that wsluc1–3 form a complex that crystallises inside the squid photophores, and that in the crystal one or more of the proteins catalyses the production of light using coelenterazine disulfate and ATP. These results suggest that ANL superfamily enzymes have independently evolved in distant species to produce light using unrelated substrates. PMID:27279452

  15. Prototype Development of the GMT Fast Steering Mirror

    NASA Astrophysics Data System (ADS)

    Kim, Young-Soo; Koh, J.; Jung, H.; Jung, H.; Cho, M. K.; Park, W.; Yang, H.; Kim, H.; Lee, K.; Ahn, H.; Park, B.

    2014-01-01

    A Fast Steering Mirror (FSM) is going to be provided as the secondary of the Giant Magellan Telescope (GMT) for the first light observations. FSM is 3.2 m in diameter and the focal ratio is 0.65. It is composed of seven circular segments which match with the primary mirror segments. Each segment contains a light-weighted mirror whose diameter is 1.1 m, and each mirror is activated by three tip-tilt actuators which compensate image degradations caused by winds and structure jitter. An FSM prototype (FSMP) has been developed to achieve the key technologies, fabrication of highly aspheric off-axis mirror and precise tip-tilt actuation. It consists of a full-size off-axis mirror segment and a tip-tilt test-bed. The development has been conducted by Korea Astronomy and Space Science Institute together with four other institutions in Korea and USA. The mirror was light-weighted by digging about a hundred holes at the backside, and the front surface has been polished. The result of computer generated hologram measurements showed the surface error of 11.7 nm rms. The tip-tilt test-bed has been manufactured and assembled. Tip-tilt range and resolution tests complied the requirements, and the attenuation test results also satisfied the performance requirements. In this paper, we present the successful developments of the prototype.

  16. Graded-index fiber tip optical tweezers: numerical simulation and trapping experiment.

    PubMed

    Gong, Yuan; Ye, Ai-Yan; Wu, Yu; Rao, Yun-Jiang; Yao, Yao; Xiao, Song

    2013-07-01

    Optical fiber tweezers based on a graded-index multimode fiber (GIMMF) tip is proposed. Light propagation characteristics and gradient force distribution near the GIMMF tip are numerically investigated, which are further compared with that of optical fiber tips based on conventional single mode fibers. The simulated results indicated that by selecting optimal GIMMF length, the gradient force of the GIMMF tip tweezers is about 4 times higher than that of the SMF tip tweezers with a same shape. To prove the feasibility of such a new concept, optical trapping of yeast cells with a diameter of ~5 μm using the chemically-etched GIMMF tip is experimentally demonstrated and the trapping force is also calculated.

  17. Medical catheters thermally manipulated by fiber optic bundles

    DOEpatents

    Chastagner, P.

    1992-10-06

    A maneuverable medical catheter comprising a flexible tube having a functional tip is described. The catheter is connected to a control source. The functional tip of the catheter carries a plurality of temperature activated elements arranged in parallel and disposed about the functional tip and held in spaced relation at each end. These elements expand when they are heated. A plurality of fiber optic bundles, each bundle having a proximal end attached to the control source and a distal end attached to one of the elements carry light into the elements where the light is absorbed as heat. By varying the optic fiber that is carrying the light and the intensity of the light, the bending of the elements can be controlled and thus the catheter steered. In an alternate embodiment, the catheter carries a medical instrument for gathering a sample of tissue. The instrument may also be deployed and operated by thermal expansion and contraction of its moving parts. 10 figs.

  18. TV Tips for Parents: Using Television To Help Your Child Learn.

    ERIC Educational Resources Information Center

    Corporation for Public Broadcasting, Washington, DC.

    Recognizing that children watch an average of 25 hours of television per week, this booklet is designed to help parents redirect their children's television viewing to higher quality programs. Ten "tips" are provided to help parents guide their children's television (TV) viewing: (1) set your child's TV schedule; (2) get involved (in the child's…

  19. Soft J-tipped guide wire-induced cardiac perforation in a patient with right ventricular lipomatosis and wall thinning.

    PubMed

    Hiroshima, Yuki; Tajima, Katsushi; Shiono, Yousuke; Suzuki, Ikuko; Kohno, Kei; Kato, Yuichi; Shunji, Kawamura; Kato, Takeo

    2012-01-01

    Cardiac tamponade caused by perforation is a rare but potentially lethal complication of central venous catheter (CVC) insertion. We herein report a case of cardiac perforation associated with the use of a soft J-tipped guide wire. Twenty minutes after the insertion of a CVC, the patient developed unexpected cardiac arrest. An autopsy revealed 400 mL of pericardial blood. The right ventricular wall was 1 mm thick with about 10 myocyte layers, which is one-third that of the normal heart. A histological analysis revealed widespread fatty infiltration of the right ventricular wall (right ventricular lipomatosis).

  20. We the People: Law Day USA 1987. 1987 Planning Guide.

    ERIC Educational Resources Information Center

    American Bar Association, Chicago, IL.

    "We the People" is the theme for the 1987 American Bar Association's 30th annual Law Day USA, observed May 1. This guide brings together information to help plan and execute programs which call attention to the principles and practices of United States law and justice. The guide contains facts about Law Day; tips for planning a Law Day…

  1. Doing Children's Museums: A Guide to 265 Hands-On Museums. Revised and Expanded.

    ERIC Educational Resources Information Center

    Cleaver, Joanne

    Noting the increase in interactive museums and science centers and children's exuberant reaction to hands-on exhibits, this guide provides tips for parents on how to prepare for a museum visit and how to encourage the learning process during the visit. The first part of the guide discusses the shift in museum policy from "hands off" to…

  2. The Thinking Student's Guide to College: 75 Tips for Getting a Better Education. Chicago Guides to Academic Life

    ERIC Educational Resources Information Center

    Roberts, Andrew

    2010-01-01

    Each fall, thousands of eager freshmen descend on college and university campuses expecting the best education imaginable: inspiring classes taught by top-ranked professors, academic advisors who will guide them to a prestigious job or graduate school, and an environment where learning flourishes outside the classroom as much as it does in lecture…

  3. Seafood Products Course Lecture Guide.

    ERIC Educational Resources Information Center

    Long, John Wingo, Ed.; And Others

    This consumer's guide offers practical information about the characteristics and uses of seafoods. It covers both finfish and shellfish, including crabs, lobsters, shrimp, oysters, clams, and scallops. It describes the characteristics, important species, fishing methods, market forms, and consumer inspection tips. It also gives such information as…

  4. Nine Steps to a Successful Lighting Retrofit.

    ERIC Educational Resources Information Center

    Ries, Jack

    1998-01-01

    Presents the steps needed to successfully design a lighting retrofit of school classrooms. Tips cover budgeting, technology, financing, contractor selection, assessing area function, and choosing a light source. (GR)

  5. Dispersion of near-infrared laser energy through radicular dentine when using plain or conical tips.

    PubMed

    Teo, Christine Yi Jia; George, Roy; Walsh, Laurence J

    2018-02-01

    The aim of this study was to investigate the influence of tip design on patterns of laser energy dispersion through the dentine of tooth roots when using near-infrared diode lasers. Diode laser emissions of 810 or 940 nm were used in combination with optical fiber tips with either conventional plain ends or conical ends, to irradiate tooth roots of oval or round cross-sectional shapes. The lasers were operated in continuous wave mode at 0.5 W for 5 s with the distal end of the fiber tip placed in the apical or coronal third of the root canal at preset positions. Laser light exiting through the roots and apical foramen was imaged, and the extent of lateral spread calculated. There was a significant difference in infrared light exiting the root canal apex between plain and conical fiber tips for both laser wavelengths, with more forward transmission of laser energy through the apex for plain tips. For both laser wavelengths, there were no significant differences in emission patterns when the variable of canal shape was used and all other variables were kept the same (plain vs conical tip, tip position). To ensure optimal treatment effect and to prevent the risks of inadvertent laser effects on the adjacent periapical tissues, it is important to have a good understanding of laser transmission characteristics of the root canal and root dentine. Importantly, it is also essential to understand transmission characteristics of plain and conical fibers tips.

  6. Assessing the irradiance delivered from light-curing units in private dental offices in Jordan.

    PubMed

    Maghaireh, Ghada A; Alzraikat, Hanan; Taha, Nessrin A

    2013-08-01

    The authors conducted a study to examine the irradiance from light-curing units (LCUs) used in dental offices in Jordan. Two of the authors visited 295 private dental offices (15 percent) in Jordan and collected the following information about the LCUs: age, type (quartz-tungsten-halogen or light-emitting diode), date of last maintenance, type of maintenance, last date of use, number of times used during the day, availability of a radiometer, exposure time for each resin-based composite increment, size of light-curing tips and presence of resin-based composite on the tips. The authors used a radiometer to measure the irradiance from the LCUs. They used linear regression with stepwise correlation for the statistical analysis. The authors set the minimum acceptable irradiance at 300 milliwatts/square centimeter. The mean irradiance of the 295 LCUs examined was 361 mW/cm(2), and 136 LCUs (46.1 percent) delivered an irradiance of less than 300 mW/cm(2). The unit's age, type and presence of resin-based composite on the light-curing tips had a significant effect on the irradiance (P ≤ .001). Only 37 of the 141 quartz-tungsten-halogen units (26.2 percent) and 122 of the 154 light-emitting diode units (79.2 percent) delivered at least 300 mW/cm(2). Resin contamination on the light-curing tips had a significant effect on the irradiance delivered. The irradiance from the LCUs decreased with use. Practical Implications. The irradiance from many of the units in this study was less than 300 mW/cm(2), which may affect the quality of resin-based composite restorations. Dentists should monitor the performance of the LCUs in their offices weekly.

  7. CT fluoroscopy guided transpleural cutting needle biopsy of small (≤2.5 cm) subpleural pulmonary nodules.

    PubMed

    Prosch, Helmut; Oschatz, Elisabeth; Eisenhuber, Edith; Wohlschlager, Helmut; Mostbeck, Gerhard H

    2011-01-01

    Small subpleural pulmonary lesions are difficult to biopsy. While the direct, short needle path has been reported to have a lower rate of pneumothorax, the indirect path provides a higher diagnostic yield. Therefore, we tried to optimize the needle pathway and minimize the iatrogenic pneumothorax risk by evaluating a CT fluoroscopy guided direct approach to biopsy subpleural lesions. Between 01/2005 and 01/2007, CT fluoroscopy guided core biopsies were performed in 24 patients. Using our technique, the tip of the guide needle remains outside the visceral pleura (17 G coaxial guide needle, 18 G Biopsy-gun, 15 or 22 mm needle path). The position of the lesion relative to the needle tip can be optimized using CT fluoroscopy by adjusting the breathing position of the patient. The Biopty gun is fired with the needle tip still outside the pleural space. Cytological smears are analyzed by a cytopathologist on-site, and biopsies are repeated as indicated with the coaxial needle still outside the pleura. Median nodule size was 1.6 cm (0.7-2.3 cm). A definitive diagnosis was obtained in 22 patients by histology and/or cytology. In one patient, only necrotic material could be obtained. In another patient, the intervention had to be aborted as the dyspnoic patient could not follow breathing instructions. An asymptomatic pneumothorax was present in seven patients; chest tube placement was not required. The presented biopsy approach has a high diagnostic yield and is especially advantageous for biopsies of small subpleural lesions in the lower lobes. Copyright © 2009 Elsevier Ireland Ltd. All rights reserved.

  8. Noise reduction and functional maps image quality improvement in dynamic CT perfusion using a new k-means clustering guided bilateral filter (KMGB).

    PubMed

    Pisana, Francesco; Henzler, Thomas; Schönberg, Stefan; Klotz, Ernst; Schmidt, Bernhard; Kachelrieß, Marc

    2017-07-01

    Dynamic CT perfusion (CTP) consists in repeated acquisitions of the same volume in different time steps, slightly before, during and slightly afterwards the injection of contrast media. Important functional information can be derived for each voxel, which reflect the local hemodynamic properties and hence the metabolism of the tissue. Different approaches are being investigated to exploit data redundancy and prior knowledge for noise reduction of such datasets, ranging from iterative reconstruction schemes to high dimensional filters. We propose a new spatial bilateral filter which makes use of the k-means clustering algorithm and of an optimal calculated guiding image. We named the proposed filter as k-means clustering guided bilateral filter (KMGB). In this study, the KMGB filter is compared with the partial temporal non-local means filter (PATEN), with the time-intensity profile similarity (TIPS) filter, and with a new version derived from it, by introducing the guiding image (GB-TIPS). All the filters were tested on a digital in-house developed brain CTP phantom, were noise was added to simulate 80 kV and 200 mAs (default scanning parameters), 100 mAs and 30 mAs. Moreover, the filters performances were tested on 7 noisy clinical datasets with different pathologies in different body regions. The original contribution of our work is two-fold: first we propose an efficient algorithm to calculate a guiding image to improve the results of the TIPS filter, secondly we propose the introduction of the k-means clustering step and demonstrate how this can potentially replace the TIPS part of the filter obtaining better results at lower computational efforts. As expected, in the GB-TIPS, the introduction of the guiding image limits the over-smoothing of the TIPS filter, improving spatial resolution by more than 50%. Furthermore, replacing the time-intensity profile similarity calculation with a fuzzy k-means clustering strategy (KMGB) allows to control the edge preserving features of the filter, resulting in improved spatial resolution and CNR both for CT images and for functional maps. In the phantom study, the PATEN filter showed overall the poorest results, while the other filters showed comparable performances in terms of perfusion values preservation, with the KMGB filter having overall the best image quality. In conclusion, the KMGB filter leads to superior results for CT images and functional maps quality improvement, in significantly shorter computational times compared to the other filters. Our results suggest that the KMGB filter might be a more robust solution for halved-dose CTP datasets. For all the filters investigated, some artifacts start to appear on the BF maps if one sixth of the dose is simulated, suggesting that no one of the filters investigated in this study might be optimal for such a drastic dose reduction scenario. © 2017 American Association of Physicists in Medicine.

  9. Analytical correlation of centrifugal compressor design geometry for maximum efficiency with specific speed

    NASA Technical Reports Server (NTRS)

    Galvas, M. R.

    1972-01-01

    Centrifugal compressor performance was examined analytically to determine optimum geometry for various applications as characterized by specific speed. Seven specific losses were calculated for various combinations of inlet tip-exit diameter ratio, inlet hub-tip diameter ratio, blade exit backsweep, and inlet-tip absolute tangential velocity for solid body prewhirl. The losses considered were inlet guide vane loss, blade loading loss, skin friction loss, recirculation loss, disk friction loss, vaneless diffuser loss, and vaned diffuser loss. Maximum total efficiencies ranged from 0.497 to 0.868 for a specific speed range of 0.257 to 1.346. Curves of rotor exit absolute flow angle, inlet tip-exit diameter ratio, inlet hub-tip diameter ratio, head coefficient and blade exit backsweep are presented over a range of specific speeds for various inducer tip speeds to permit rapid selection of optimum compressor size and shape for a variety of applications.

  10. Interactive effects of juvenile defoliation, light conditions, and interspecific competition on growth and ectomycorrhizal colonization of Fagus sylvatica and Pinus sylvestris seedlings.

    PubMed

    Trocha, Lidia K; Weiser, Ewa; Robakowski, Piotr

    2016-01-01

    Seedlings of forest tree species are exposed to a number of abiotic (organ loss or damage, light shortage) and biotic (interspecific competition) stress factors, which may lead to an inhibition of growth and reproduction and, eventually, to plant death. Growth of the host and its mycorrhizal symbiont is often closely linked, and hence, host damage may negatively affect the symbiont. We designed a pot experiment to study the response of light-demanding Pinus sylvestris and shade-tolerant Fagus sylvatica seedlings to a set of abiotic and biotic stresses and subsequent effects on ectomycorrhizal (ECM) root tip colonization, seedling biomass, and leaf nitrogen content. The light regime had a more pronounced effect on ECM colonization than did juvenile damage. The interspecific competition resulted in higher ECM root tip abundance for Pinus, but this effect was insignificant in Fagus. Low light and interspecific competition resulted in lower seedling biomass compared to high light, and the effect of the latter was partially masked by high light. Leaf nitrogen responded differently in Fagus and Pinus when they grew in interspecific competition. Our results indicated that for both light-demanding (Pinus) and shade-tolerant (Fagus) species, the light environment was a major factor affecting seedling growth and ECM root tip abundance. The light conditions favorable for the growth of seedlings may to some extent compensate for the harmful effects of juvenile organ loss or damage and interspecific competition.

  11. Effect of various infection-control methods for light-cure units on the cure of composite resins.

    PubMed

    Chong, S L; Lam, Y K; Lee, F K; Ramalingam, L; Yeo, A C; Lim, C C

    1998-01-01

    This study (1) compared the curing-light intensity with various barrier infection-control methods used to prevent cross contamination, (2) compared the Knoop hardness value of cured composite resin when various barrier control methods were used, and (3) correlated the hardness of the composite resin with the light-intensity output when different infection-control methods were used. The light-cure unit tips were covered with barriers, such as cellophane wrap, plastic gloves, Steri-shields, and finger cots. The control group had no barrier. Composite resins were then cured for each of the five groups, and their Knoop hardness values recorded. The results showed that there was significant statistical difference in the light-intensity output among the five groups. However, there was no significant statistical difference in the Knoop hardness values among any of the groups. There was also no correlation between the Knoop hardness value of the composite resin with the light-intensity output and the different infection-control methods. Therefore, any of the five infection-control methods could be used as barriers for preventing cross-contamination of the light-cure unit tip, for the light-intensity output for all five groups exceeded the recommended value of 300 W/m2. However, to allow a greater margin of error in clinical situations, the authors recommend that the plastic glove or the cellophane wrap be used to wrap the light-cure tip, since these barriers allowed the highest light-intensity output.

  12. Compact Packaging of Photonic Millimeter-Wave Receiver

    NASA Technical Reports Server (NTRS)

    Nguyen, Hung; Pouch, John; Miranda, Felix; Levi, Anthony F.

    2007-01-01

    A carrier structure made from a single silicon substrate is the basis of a compact, lightweight, relatively inexpensive package that holds the main optical/electronic coupling components of a photonic millimeter-wave receiver based on a lithium niobate resonator disk. The design of the package is simple and provides for precise relative placement of optical components, eliminating the need for complex, bulky positioning mechanisms like those commonly used to align optical components to optimize focus and coupling. Although a prototype of the package was fabricated as a discrete unit, the design is amenable to integration of the package into a larger photonic and/or electronic receiver system. The components (see figure) include a lithium niobate optical resonator disk of 5-mm diameter and .200- m thickness, positioned adjacent to a millimeter- wave resonator electrode. Other components include input and output coupling prisms and input and output optical fibers tipped with ball lenses for focusing and collimation, respectively. Laser light is introduced via the input optical fiber and focused into the input coupling prism. The input coupling prism is positioned near (but not in contact with) the resonator disk so that by means of evanescent-wave coupling, the input laser light in the prism gives rise to laser light propagating circumferentially in guided modes in the resonator disk. Similarly, a portion of the circumferentially propagating optical power is extracted from the disk by evanescent-wave coupling from the disk to the output coupling prism, from whence the light passes through the collimating ball lens into the output optical fiber. The lens-tipped optical fibers must be positioned at a specified focal distance from the prisms. The optical fibers and the prisms must be correctly positioned relative to the resonator disk and must be oriented to obtain the angle of incidence (55 in the prototype) required for evanescent-wave coupling of light into and out of the desired guided modes in the resonator disk. To satisfy all these requirements, precise alignment features are formed in the silicon substrate by use of a conventional wet-etching process. These features include a 5-mm-diameter, 50- m-deep cavity that holds the disk; two trapezoidal-cross-section recesses for the prisms; and two grooves that hold the optical fibers at the correct positions and angles relative to the prisms and disk. The fiber grooves contain abrupt tapers, near the prisms, that serve as hard stops for positioning the lenses at the focal distance from the prisms. There are also two grooves for prismadjusting rods. The design provides a little slack in the prism recesses for adjusting the positions of the prisms by means of these rods to optimize the optical coupling.

  13. Factors Influencing Intracavitary Electrocardiographic P-Wave Changes during Central Venous Catheter Placement

    PubMed Central

    Wang, Guorong; Guo, Ling; Jiang, Bin; Huang, Min; Zhang, Jian; Qin, Ying

    2015-01-01

    Amplitude changes in the P-wave of intracavitary electrocardiography have been used to assess the tip placement of central venous catheters. The research assessed the sensitivity and specificity of this sign in comparison with standard radiographic techniques for tip location, focusing on factors influencing its clinical utility. Both intracavitary electrocardiography guided tip location and X-ray positioning were used to verify catheter tip locations in patients undergoing central venous catheter insertion. Intracavitary electrocardiograms from 1119 patients (of a total 1160 subjects) showed specific amplitude changes in the P-wave. As the results show, compared with X-ray positioning, the sensitivity of electrocardiography-guided tip location was 97.3%, with false negative rate of 2.7%; the specificity was 1, with false positive rate of zero. Univariate analyses indicated that features including age, gender, height, body weight, and heart rate have no statistically significant influence on P-wave amplitude changes (P>0.05). Multivariate logistic regression revealed that catheter insertion routes (OR = 2.280, P = 0.003) and basal P-wave amplitude (OR = 0.553, P = 0.003) have statistically significant impacts on P-wave amplitude changes. As a reliable indicator of tip location, amplitude change in the P-wave has proved of good sensitivity and excellent specificity, and the minor, zero, false positive rate supports the clinical utility of this technique in early recognition of malpositioned tips. A better sensitivity was achieved in placement of centrally inserted central catheters (CICCs) than that of peripherally inserted central catheters (PICCs). In clinical practice, a combination of intracavitary electrocardiography, ultrasonic inspection and the anthropometric measurement method would further improve the accuracy. PMID:25915758

  14. Teaching with Interactive Multimedia.

    ERIC Educational Resources Information Center

    Hudson, Tim

    Based on the idea that anyone who is interested in making entertaining and informative presentations in educational settings is interested in multimedia, this practical guide offers tips for communication (and other) teachers who want to integrate and program interactive multimedia into their courses. The guide suggests that teachers on limited…

  15. Implementing Guided Pathways: Tips and Tools

    ERIC Educational Resources Information Center

    Bailey, Thomas; Jaggars, Shanna Smith; Jenkins, Davis

    2015-01-01

    A growing number of community colleges and four-year universities are seeking to improve student outcomes by redesigning academic programs and student support services following the guided pathways approach. These institutions are mapping out highly structured, educationally coherent program pathways for students to follow by starting with the end…

  16. The Primary Teacher's Survival Guide.

    ERIC Educational Resources Information Center

    Heyda, Pamela A.

    This guide for primary school teachers presents commonly asked questions and answers. Chapter 1, "How Do I Set Up My Classroom?" discusses desk and furniture arrangement. Chapter 2, "How Do I Survive the First Days of School?" offers tips for meeting and greeting students, establishing routines, and presenting activities.…

  17. Photonic jet: key role of injection for etchings with a shaped optical fiber tip.

    PubMed

    Pierron, Robin; Zelgowski, Julien; Pfeiffer, Pierre; Fontaine, Joël; Lecler, Sylvain

    2017-07-15

    We demonstrate the key role of the laser injection into a multimode fiber to obtain a photonic jet (PJ). PJ, a high concentrated propagating beam with a full width at half-maximum smaller than the diffraction limit, is here generated with a shaped optical fiber tip using a pulsed laser source (1064 nm, 100 ns, 35 kHz). Three optical injection systems of light are compared. For similar etched marks on silicon with diameters around 1 μm, we show that the required ablation energy is minimum when the injected light beam is close to the fundamental mode diameter of the fiber. Thus, we confirm experimentally that to obtain a PJ out of an optical fiber, light injection plays a role as important as that of the tip shape and, therefore, the role of the fundamental mode in the process.

  18. Winter Survival: A Consumer's Guide to Winter Preparedness.

    ERIC Educational Resources Information Center

    Department of Energy, Washington, DC.

    This booklet discusses a variety of topics to help consumers prepare for winter. Tips for the home include: winterizing the home, dealing with a loss of heat or power failure, and what you need to have on hand. Another section gives driving tips and what to do in a storm. Health factors include suggestions for keeping warm, signs and treatment for…

  19. Ultrasound-guided transhepatic puncture of the hepatic veins for TIPS placement.

    PubMed

    Gazzera, C; Fonio, P; Gallesio, C; Camerano, F; Doriguzzi Breatta, A; Righi, D; Veltri, A; Gandini, G

    2013-04-01

    This retrospective analysis was carried out to assess the feasibility and results of transjugular intrahepatic portal systemic shunt (TIPS) performed with ultrasound (US)-guided percutaneous puncture of the hepatic veins. Over a period of 3 years, 153 patients were treated with TIPS at our centre. In eight cases, a percutaneous puncture of the middle (n=7) or right (n=1) hepatic vein was required because the hepatic vein ostium was not accessible. Indications for TIPS were bleeding (n=1), Budd-Chiari syndrome (n=1), ascites (n=2), reduced portal flow (n=1) and incomplete portal thrombosis (n=3). A 0.018-in. guidewire was anterogradely introduced into the hepatic vein to the inferior vena cava (IVC) through a 21-gauge needle. In the meantime, a 25-mm snare-loop catheter was introduced through the jugular access to retrieve the guidewire, achieving through-andthrough access. Then, a Rosch-Uchida set was used to place the TIPS with the traditional technique. Technical success was achieved in all patients. There was one case of stent thrombosis. One patient died of pulmonary oedema. Three patients were eligible for liver transplantation, whereas the others were excluded due to shunt thrombosis (n=1) and previous nonhepatic neoplasms (n=3). The percutaneous approach to hepatic veins is rapid and safe and may be useful for avoiding traumatic liver injuries.

  20. Intravascular Ultrasound Guidance for Transjugular Intrahepatic Portosystemic Shunt Procedure in a Swine Model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kew, Jacqueline; Davies, Roger P.

    2004-01-15

    A new method is described for guiding hepato-portalvenous puncture using a longitudinal side-view intravascular ultrasound(L-IVUS) transducer to assist in the performance of transjugularintrahepatic portosystemic shunt (TIPS) in three Australian swine.Simultaneous L-IVUS with an AcuNav (registered) 5-10 MHz 10 Fr transducer(Acuson Corporation, Mountain View, CA, USA) and fluoroscopy guidance was used to image and monitor the hepatic to portal venous puncture,dilatation of the tract, and deployment of the TIPS stent. Flow through the shunt could be demonstrated with both L-IVUS and angiography. TIPS was successful in all swine. The time for portal vein puncture once the target portal vein was identifiedmore » was reduced at each attempt. The number of portal vein puncture attempts was 2, 1, and 1. No post-procedural complication was evident. L-IVUS-guided TIPS is practical and has the potential to improve safety by permitting simultaneous ultrasound and fluoroscopic imaging of the needle and target vascular structures. This technique allows for a more streamlined approach to TIPS, decreasing the fluoroscopic time (hence,decreasing the radiation exposure to the staff and patient) and anesthetic time. In addition, there are improved safety benefits obviating the need for wedged portography, facilitating avoidance of bile duct and hepatic arterial puncture, and minimizing hepatic injury by decreasing liver capsular puncture and the attendant risks.« less

  1. Prototype of a laser guide star wavefront sensor for the Extremely Large Telescope

    NASA Astrophysics Data System (ADS)

    Patti, M.; Lombini, M.; Schreiber, L.; Bregoli, G.; Arcidiacono, C.; Cosentino, G.; Diolaiti, E.; Foppiani, I.

    2018-06-01

    The new class of large telescopes, like the future Extremely Large Telescope (ELT), are designed to work with a laser guide star (LGS) tuned to a resonance of atmospheric sodium atoms. This wavefront sensing technique presents complex issues when applied to big telescopes for many reasons, mainly linked to the finite distance of the LGS, the launching angle, tip-tilt indetermination and focus anisoplanatism. The implementation of a laboratory prototype for the LGS wavefront sensor (WFS) at the beginning of the phase study of MAORY (Multi-conjugate Adaptive Optics Relay) for ELT first light has been indispensable in investigating specific mitigation strategies for the LGS WFS issues. This paper presents the test results of the LGS WFS prototype under different working conditions. The accuracy within which the LGS images are generated on the Shack-Hartmann WFS has been cross-checked with the MAORY simulation code. The experiments show the effect of noise on centroiding precision, the impact of LGS image truncation on wavefront sensing accuracy as well as the temporal evolution of the sodium density profile and LGS image under-sampling.

  2. Plasmonic superfocusing on metallic tips for near-field optical imaging and spectroscopy

    NASA Astrophysics Data System (ADS)

    Neacsu, Catalin C.; Olmon, Rob; Berweger, Samuel; Kappus, Alexandria; Kirchner, Friedrich; Ropers, Claus; Saraf, Lax; Raschke, Markus B.

    2008-03-01

    Realization of localized light sources through nonlocal excitation is important in the context of plasmon photonics, molecular sensing, and in particular near-field optical techniques. Here, the efficient conversion of propagating surface plasmons, launched on the shaft of a scanning probe tip, into localized plasmon at the apex provides a true nanoconfined light source. Focused ion beam milling is used to generate periodic surface nanostructures on the tip shaft that allow for tailoring the plasmon excitation. Using ultrashort visible and mid-IR transients the dynamics of the propagation and subsequent scattered emission is characterized. The strong field enhancement and spatial field confinement at the apex is demonstrated studying the coupling of the tip in near-field interaction with a flat sample surface. It is used in scattering near-field spectroscopic imaging (s-SNOM) to probe surface nanostructures with spatial resolution down to 10 nm.

  3. Label-free optical imaging of membrane patches for atomic force microscopy

    PubMed Central

    Churnside, Allison B.; King, Gavin M.; Perkins, Thomas T.

    2010-01-01

    In atomic force microscopy (AFM), finding sparsely distributed regions of interest can be difficult and time-consuming. Typically, the tip is scanned until the desired object is located. This process can mechanically or chemically degrade the tip, as well as damage fragile biological samples. Protein assemblies can be detected using the back-scattered light from a focused laser beam. We previously used back-scattered light from a pair of laser foci to stabilize an AFM. In the present work, we integrate these techniques to optically image patches of purple membranes prior to AFM investigation. These rapidly acquired optical images were aligned to the subsequent AFM images to ~40 nm, since the tip position was aligned to the optical axis of the imaging laser. Thus, this label-free imaging efficiently locates sparsely distributed protein assemblies for subsequent AFM study while simultaneously minimizing degradation of the tip and the sample. PMID:21164738

  4. Make a Difference in Your School: A How-to Guide for Engaging Students in Resource Conservation and Waste Reduction

    ERIC Educational Resources Information Center

    US Environmental Protection Agency, 2006

    2006-01-01

    The U.S. Environmental Protection Agency (EPA) developed this guide to provide advice, ideas, and inspiration to teachers, school administrators, and others for planning a hands-on environmental day at school. Many of the tips and ideas in this guide come from "Make a Difference Day" events supported by EPA. EPA launched its "Make a…

  5. Patient Activated Care for Rural Elderly. A Program Development and Teaching Guide for Planners, Facilitators, and Coordinators.

    ERIC Educational Resources Information Center

    Gaarder, Lorin R.; Cohen, Saul

    This guide is an outline for developing and presenting programs in self health care for senior citizens. The guide is presented in two sections. The first section provides background information about elderly self-care and tips on teaching it and developing a program. Sample letters to prospective enrollees and sample news releases are included.…

  6. 4. Light tower, view southeast, north and west sides ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Light tower, view southeast, north and west sides - Great Duck Island Light Station, At southern tip of Great Duck Island southeast of Bass Harbor & northeast of Frenchboro, Frenchboro, Hancock County, ME

  7. 5. Light tower, newel post and stairs, looking east ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Light tower, newel post and stairs, looking east - Great Duck Island Light Station, At southern tip of Great Duck Island southeast of Bass Harbor & northeast of Frenchboro, Frenchboro, Hancock County, ME

  8. [Three-dimensional finite element analysis of maxillary anterior teeth retraction force system in light wire technique].

    PubMed

    Zhang, Xiangfeng; Wang, Chao; Xia, Xi; Deng, Feng; Zhang, Yi

    2015-06-01

    This study aims to construct a three-dimensional finite element model of a maxillary anterior teeth retraction force system in light wire technique and to investigate the difference of hydrostatic pressure and initial displacement of upper anterior teeth under different torque values of tip back bend. A geometric three-dimensional model of the maxillary bone, including all the upper teeth, was achieved via CT scan. To construct the force model system, lingual brackets and wire were constructed by using the Solidworks. Brackets software, and wire were assembled to the teeth. ANASYS was used to calculate the hydrostatic pressure and the initial displacement of maxillary anterior teeth under different tip-back bend moments of 15, 30, 45, 60, and 75 Nmm when the class II elastic force was 0.556 N. Hydrostatic pressure was concentrated in the root apices and cervical margin of upper anterior teeth. Distal tipping and relative intrusive displacement were observed. The hydrostatic pressure and initial displacement of upper canine were greater than in the central and lateral incisors. This hydrostatic pressure and initial intrusive displacement increased with an increase in tip-back bend moment. Lingual retraction force system of maxillary anterior teeth in light wire technique can be applied safely and controllably. The type and quantity of teeth movement can be controlled by the alteration of tip-back bend moment.

  9. The Music Industry Conference Guide for Music Educators. A Supplement to the Music Educators Journal.

    ERIC Educational Resources Information Center

    Music Educators Journal, 1988

    1988-01-01

    This supplement is a comprehensive guide to the music industry designed for music teachers. Included are tips for contacting music businesses and suggestions on ordering music, robes, instruments, computer software, and other supplies. Includes an annotated directory of Music Industry Conference members. (JDH)

  10. The School Leader's Guide to Social Media

    ERIC Educational Resources Information Center

    Williamson, Ronald; Johnston, J. Howard

    2012-01-01

    Social media has exploded onto American culture--including our schools--giving educators a unique opportunity to shape this phenomenon into a powerful tool for improving educational leadership practices. With real-world examples and practical tips, this essential guide shows school leaders how to address both the potential benefits and common…

  11. Handy Reference Guide to the Fair Labor Standards Act.

    ERIC Educational Resources Information Center

    Employment Standards Administration (DOL), Washington, DC. Wage and Hour Div.

    This guide provides general information about the application of the Fair Labor Standards Act (FLSA), as amended. Topics covered are basic wage standards, employees covered, tipped employees, employer-furnished facilities, subminimum wage provisions, equal pay provisions, exemptions, child labor provisions, recordkeeping, terms used in the FLSA,…

  12. Building Big with David Macaulay. Activity Guide.

    ERIC Educational Resources Information Center

    Sammons, James; Sammons, Fran Lyons; Curtis, Paul

    This activity guide is designed for educators and features suggestions for possible activity paths for different amounts of available time and survival tips for activity leaders. Each activity is divided into two sections--educator ideas and activity handouts. Activity sections include: (1) Foundations; (2) Bridges; (3) Domes; (4) Skyscrapers; (5)…

  13. Technique for CT Fluoroscopy-Guided Lumbar Medial Branch Blocks and Radiofrequency Ablation.

    PubMed

    Amrhein, Timothy J; Joshi, Anand B; Kranz, Peter G

    2016-09-01

    The purpose of this study is to describe the procedure for CT fluoroscopy-guided lumbar medial branch blocks and facet radiofrequency ablation. CT fluoroscopic guidance allows more-precise needle tip positioning and is an alternative method for performing medial branch blocks and facet radiofrequency ablation.

  14. Clues about Reading Enrichment (CARE).

    ERIC Educational Resources Information Center

    Daly, Nancy Jo; And Others

    Compiled by members of the Reading Committee of the North Middlesex Regional School District (Massachusetts), this illustrated guide provides tips, suggestions, and activities that parents can follow at home to help their children read. The Clues about Reading Enrichment (CARE) guide notes that regularly reading aloud to and with children is an…

  15. Trafficking and Health: A Systematic Review of Research Methods.

    PubMed

    Cannon, Abby C; Arcara, Jennet; Graham, Laurie M; Macy, Rebecca J

    2018-04-01

    Trafficking in persons (TIP) is a human rights violation with serious public health consequences. Unfortunately, assessing TIP and its health sequelae rigorously and reliably is challenging due to TIP's clandestine nature, variation in definitions of TIP, and the need to use research methods that ensure studies are ethical and feasible. To help guide practice, policy, and research to assess TIP and health, we undertook a systematic literature review of 70 peer-reviewed, published articles to (a) identify TIP and health research methods being used, (b) determine what we can learn about TIP and health from these varied methodologies, and (c) determine the gaps that exist in health-focused TIP research. Results revealed that there are various quantitative and qualitative data collection and analysis methods being used to investigate TIP and health. Furthermore, findings show that the limitations of current methodologies affect what is known about TIP and health. In particular, varying definitions, participant recruitment strategies, ethical standards, and outcome measures all affect what is known about TIP and health. Moreover, findings demonstrate an urgent need for representative and nonpurposive recruitment strategies in future investigations of TIP and health as well as research on risk and protective factors related to TIP and health, intervention effectiveness, long-term health outcomes, and research on trafficked people beyond women trafficked for sex. We offer recommendations for research, policy, and practice based on review results.

  16. Size-dependent longitudinal plasmon resonance wavelength and extraordinary scattering properties of Au nanobipyramids.

    PubMed

    Wang, Wenhao; Yu, Peng; Zhong, Zhiqin; Tong, Xin; Liu, Tianji; Li, Yanbo; Ashalley, Eric; Chen, Huanyang; Wu, Jiang; Wang, Zhiming

    2018-08-31

    Au nanobipyramids (NBPs) with sharp tips and narrow plasmon linewidths are ideal candidates for plasmonic applications. In this paper, we investigated the influencing factors of longitudinal plasmon resonance wavelength (LPRW) and scattering properties of single Au NBP by simulation. Compared with the volume, we establish the aspect ratio (length/width) as the dominant factor that affects the LPRW of Au NBPs. Plasmonic nanoparticles have been widely used for light-trapping enhancement in photovoltaics. To give a profound understanding of the superior light harvesting properties of Au NBPs, the near-field localization effect and far-field scattering mechanism of Au NBPs were investigated. Under the light injection at LPRW, the tip area shows near-field enhancement and the maximum scattering intensity appears on the side area of the waist owing to the remarkable optical absorption near the tips. Additionally, we confirm the fraction of light scattered into the substrate and angular distribution of the light scattered by the Au NBPs. The fraction of light scattered into the substrate reaches up to 97% from 400-1100 nm and preserves a broadband spectrum. This suggests that the NBP has a predominant forward scattering and reduced backward scattering. The excellent plasmonic scattering properties of Au NBPs are promising in photovoltaic devices and photothermal therapy.

  17. Peroperative electrocardiographic control of catheter tip position during implantation of femoral venous ports.

    PubMed

    Gibault, Pierre; Desruennes, Eric; Bourgain, Jean-Louis

    2015-01-01

    Electrocardiographic (ECG) guidance has been shown to be as effective than fluoroscopy to position the tip of central venous devices close to the superior vena cava (SVC)-right atrium (RA) junction. When SVC access is contraindicated, a femoral access may be used. The aim of this prospective study is to evaluate the effectiveness of ECG guidance to position the tip of femoral ports at inferior vena cava (IVC)-RA junction. Inclusion criterion was the need for femoral port implantation. After insertion of the dilator in the femoral vein, the catheter with the guide wire inside was introduced and the ECG signal collected at the tip of the guide (Celsite™ ECG, B. Braun, Germany) or via saline injected in the catheter (Nautilus™, Perouse, France). Fluoroscopy was performed at each change of the P-wave from IVC to RA. A final X-ray was performed after withdrawing the catheter 2 cm below the first P-wave change. A total of 18 patients were included between December 2011 and June 2013. The P-wave was most often negative in IVC, biphasic when the catheter entered RA and giant and positive at the top of RA. When the catheter was withdraw 2 cm below the first biphasic P-wave the tip was just below the IVC-RA junction in 17 patients. In one patient P-wave changes were not significant and the final position was adjusted under fluoroscopy. ECG guidance is effective to assess catheter tip position during femoral port placement and avoids the need for radiological methods.

  18. Extended Glauert tip correction to include vortex rollup effects

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Maniaci, David; Schmitz, Sven

    Wind turbine loads predictions by blade-element momentum theory using the standard tip-loss correction have been shown to over-predict loading near the blade tip in comparison to experimental data. This over-prediction is theorized to be due to the assumption of light rotor loading, inherent in the standard tip-loss correction model of Glauert. A higher- order free-wake method, WindDVE, is used to compute the rollup process of the trailing vortex sheets downstream of wind turbine blades. Results obtained serve an exact correction function to the Glauert tip correction used in blade-element momentum methods. Lastly, it is found that accounting for the effectsmore » of tip vortex rollup within the Glauert tip correction indeed results in improved prediction of blade tip loads computed by blade-element momentum methods.« less

  19. Extended Glauert tip correction to include vortex rollup effects

    DOE PAGES

    Maniaci, David; Schmitz, Sven

    2016-10-03

    Wind turbine loads predictions by blade-element momentum theory using the standard tip-loss correction have been shown to over-predict loading near the blade tip in comparison to experimental data. This over-prediction is theorized to be due to the assumption of light rotor loading, inherent in the standard tip-loss correction model of Glauert. A higher- order free-wake method, WindDVE, is used to compute the rollup process of the trailing vortex sheets downstream of wind turbine blades. Results obtained serve an exact correction function to the Glauert tip correction used in blade-element momentum methods. Lastly, it is found that accounting for the effectsmore » of tip vortex rollup within the Glauert tip correction indeed results in improved prediction of blade tip loads computed by blade-element momentum methods.« less

  20. Simulation study of core heating properties for recent FIREX-I experiments

    NASA Astrophysics Data System (ADS)

    Johzaki, Tomoyuki; Kai, Yusuke; Endo, Takuma; Nagatomo, Hideo; Sunahara, Atsushi; Sentoku, Yasuhiko; Taguchi, Toshihiro; Fujioka, Shinsuke; Shiraga, Hiroyuki; Azechi, Hiroshi; Firex Project Team

    2016-10-01

    The demonstration of efficient core heating is the main purpose of FIREX-I project, where Au cone-attached solid ball CD target is used. For the guiding of fast electron beam generated by relativistic laser plasma interactions, the kilo-Tesla-class longitudinal magnetic field is applied by a capacitor-coil target and kJ-class ns-durration high power laser. In addition, to reduce the collisional effect (energy loss and scattering of fast electrons) during propagation in the Au cone tip, we introduced opened-tip cone (tipless cone). To evaluate the core heating properties, we carried out the integrated simulations, which shows the enhancement of core heating efficiency due to the magnetic guiding and opened-tip cone by a factor of three. These simulation results will be shown and be compared with the experimental results. JSPS KAKENHI (26400532, 15H03758, 16H02245, 15K21767), NIFS Collaboration Research program (NIFS12KUGK05, NIFS14KNSS054), and FIREX project.

  1. Pull-Through Technique for Recanalization of Occluded Portosystemic Shunts (TIPS): Technical Note and Review of the Literature

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tanaka, Toshihiro, E-mail: toshihir@bf6.so-net.ne.jp; Guenther, Rolf W., E-mail: guenther@rad.rwth-aachen.de; Isfort, Peter, E-mail: isfort@hia.rwth-aachen.de

    Transjugular intrahepatic portosystemic shunt (TIPS) dysfunction is an important problem after creation of shunts. Most commonly, TIPS recanalization is performed via the jugular vein approach. Occasionally it is difficult to cross the occlusion. We describe a hybrid technique for TIPS revision via a direct transhepatic access combined with a transjugular approach. In two cases, bare metal stents or polytetrafluoroethylene (PTFE)-covered stent grafts had been placed in TIPS tract previously, and they were completely obstructed. The tracts were inaccessible via the jugular vein route alone. In each case, after fluoroscopy or computed tomography-guided transhepatic puncture of the stented segment of themore » TIPS, a wire was threaded through the shunt and snared into the right jugular vein. The TIPS was revised by balloon angioplasty and additional in-stent placement of PTFE-covered stent grafts. The patients were discharged without any complications. Doppler sonography 6 weeks after TIPS revision confirmed patency in the TIPS tract and the disappearance of ascites. We conclude that this technique is feasible and useful, even in patients with previous PTFE-covered stent graft placement.« less

  2. Integrated Fiber-Optic Light Probe: Measurement of Static Deflections in Rotating Turbomachinery

    NASA Technical Reports Server (NTRS)

    Kurkov, Anatole P.

    1998-01-01

    At the NASA Lewis Research Center, in cooperation with Integrated Fiber Optic Systems, Inc., an integrated fiber-optic light probe system was designed, fabricated, and tested for monitoring blade tip deflections, vibrations, and to some extent, changes in the blade tip clearances of a turbomachinery fan or a compressor rotor. The system comprises a set of integrated fiber-optic light probes that are positioned to detect the passing blade tip at the leading and trailing edges. In this configuration, measurements of both nonsynchronous blade vibrations and steady-state blade deflections can be made from the timing information provided by each light probe-consisting of an integrated fiber-optic transmitting channel and numerical aperture receiving fibers, all mounted in the same cylindrical housing. With integrated fiber-optic technology, a spatial resolution of 50 mm is possible while the outer diameter is kept below 2.5 mm. To evaluate these probes, we took measurements in a single-stage compressor facility and an advanced fan rig in Lewis' 9- by 15-Foot Low-Speed Wind Tunnel.

  3. Health and Family Living. Teacher Guidebook and Student Activity Book. Adult Basic Education Project REAL: Relevant Education for Adult Learners.

    ERIC Educational Resources Information Center

    Edgar, S. Keith

    This packet contains both a teacher's guide and a student activity book designed to help adult students learn about health and family living. Both booklets cover the following topics: health in the home, safety in the home (safety tips concerning children, tips on indoor safety, first aid), helping children with school activities, leisure time and…

  4. Tips for Kids: Lower Your Risk for Type 2 Diabetes

    ERIC Educational Resources Information Center

    US Department of Health and Human Services, 2005

    2005-01-01

    Today, more kids have type 2 diabetes than ever before. This colorful, easy-to-read tip sheet encourages young people to take steps to lower their risk for type 2 diabetes. A list of warning signs and a healthy eating guide is offered, along with a list of websites to learn more. [This brochure was prepared by the Department of Health and Human…

  5. I Can Soar: How Technology Helps Students Take Off. A Resource Kit for Parents, Educators, and School Administrators Who Work with Students Who Have Disabilities.

    ERIC Educational Resources Information Center

    Gruner, Allison; Fleming, Erin; Bradley, Carl; Diamond, Christina M.; Ruedel, Kristin L. A.; Saunders, Jessica; Paulsen, Christine; McInerney, Maurice

    This resource kit includes the following: Executive Summary; Legal Fact Sheet; Resource Guide; 26-minute "I Can Soar" Videotape; Video User's Guide; and Stories of Students Featured in Video. The materials provide tips to hep guide consumers in better integrating assistive technology (AT) within effective programs and services for children with…

  6. Fabrication and characterization of cylindrical light diffusers comprised of shape memory polymer.

    PubMed

    Small, Ward; Buckley, Patrick R; Wilson, Thomas S; Loge, Jeffrey M; Maitland, Kristen D; Maitland, Duncan J

    2008-01-01

    We developed a technique for constructing light diffusing devices comprised of a flexible shape memory polymer (SMP) cylindrical diffuser attached to the tip of an optical fiber. The devices are fabricated by casting an SMP rod over the cleaved tip of an optical fiber and media blasting the SMP rod to create a light diffusing surface. The axial and polar emission profiles and circumferential (azimuthal) uniformity are characterized for various blasting pressures, nozzle-to-sample distances, and nozzle translation speeds. The diffusers are generally strongly forward-directed and consistently withstand over 8 W of incident IR laser light without suffering damage when immersed in water. These devices are suitable for various endoluminal and interstitial biomedical applications.

  7. Fabrication and characterization of cylindrical light diffusers comprised of shape memory polymer

    PubMed Central

    Small, Ward; Buckley, Patrick R.; Wilson, Thomas S.; Loge, Jeffrey M.; Maitland, Kristen D.; Maitland, Duncan J.

    2009-01-01

    We developed a technique for constructing light diffusing devices comprised of a flexible shape memory polymer (SMP) cylindrical diffuser attached to the tip of an optical fiber. The devices are fabricated by casting an SMP rod over the cleaved tip of an optical fiber and media blasting the SMP rod to create a light diffusing surface. The axial and polar emission profiles and circumferential (azimuthal) uniformity are characterized for various blasting pressures, nozzle-to-sample distances, and nozzle translation speeds. The diffusers are generally strongly forward-directed and consistently withstand over 8 W of incident IR laser light without suffering damage when immersed in water. These devices are suitable for various endoluminal and interstitial biomedical applications. PMID:18465981

  8. Single and dual fiber nano-tip optical tweezers: trapping and analysis.

    PubMed

    Decombe, Jean-Baptiste; Huant, Serge; Fick, Jochen

    2013-12-16

    An original optical tweezers using one or two chemically etched fiber nano-tips is developed. We demonstrate optical trapping of 1 micrometer polystyrene spheres at optical powers down to 2 mW. Harmonic trap potentials were found in the case of dual fiber tweezers by analyzing the trapped particle position fluctuations. The trap stiffness was deduced using three different models. Consistent values of up to 1 fN/nm were found. The stiffness linearly decreases with decreasing light intensity and increasing fiber tip-to-tip distance.

  9. 2. Keeper's house, light tower and bell house, view east, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Keeper's house, light tower and bell house, view east, west and south sides - Bass Harbor Head Light Station, At southwest tip of Mount Desert Island off State Route 102, Bass Harbor, Hancock County, ME

  10. Electromagnetic-Tracked Biopsy under Ultrasound Guidance: Preliminary Results

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hakime, Antoine, E-mail: thakime@yahoo.com; Deschamps, Frederic; Marques De Carvalho, Enio Garcia

    2012-08-15

    Purpose: This study was designed to evaluate the accuracy and safety of electromagnetic needle tracking for sonographically guided percutaneous liver biopsies. Methods: We performed 23 consecutive ultrasound-guided liver biopsies for liver nodules with an electromagnetic tracking of the needle. A sensor placed at the tip of a sterile stylet (18G) inserted in a coaxial guiding trocar (16G) used for biopsy was localized in real time relative to the ultrasound imaging plane, thanks to an electromagnetic transmitter and two sensors on the ultrasound probe. This allows for electronic display of the needle tip location and the future needle path overlaid onmore » the real-time ultrasound image. Distance between needle tip position and its electronic display, number of needle punctures, number of needle pull backs for redirection, technical success (needle positioned in the target), diagnostic success (correct histopathology result), procedure time, and complication were evaluated according to lesion sizes, depth and location, operator experience, and 'in-plane' or 'out-of-plane' needle approach. Results: Electronic display was always within 2 mm from the real position of the needle tip. The technical success rate was 100%. A single needle puncture without repuncture was used in all patients. Pull backs were necessary in six patients (26%) to obtain correct needle placement. The overall diagnostic success rate was 91%. The overall true-positive, true-negative, false-negative, and failure rates of the biopsy were 100% (19/19) 100% (2/2), 0% (0/23), and 9% (2/23). The median total procedure time from the skin puncture to the needle in the target was 30 sec (from 5-60 s). Lesion depth and localizations, operator experience, in-plane or out-of-plane approach did not affect significantly the technical, diagnostic success, or procedure time. Even when the tumor size decreased, the procedure time did not increase. Conclusions: Electromagnetic-tracked biopsy is accurate to determine needle tip position and allows fast and accurate needle placement in targeted liver nodules.« less

  11. Chemically etched fiber tips for near-field optical microscopy: a process for smoother tips.

    PubMed

    Lambelet, P; Sayah, A; Pfeffer, M; Philipona, C; Marquis-Weible, F

    1998-11-01

    An improved method for producing fiber tips for scanning near-field optical microscopy is presented. The improvement consists of chemically etching quartz optical fibers through their acrylate jacket. This new method is compared with the previous one in which bare fibers were etched. With the new process the meniscus formed by the acid along the fiber does not move during etching, leading to a much smoother surface of the tip cone. Subsequent metallization is thus improved, resulting in better coverage of the tip with an aluminum opaque layer. Our results show that leakage can be avoided along the cone, and light transmission through the tip is spatially limited to an optical aperture of a 100-nm dimension.

  12. Talking with Kids: A Parent's Guide to Sex Education.

    ERIC Educational Resources Information Center

    National PTA, Chicago, IL.

    This guide is designed to help parents determine what is being taught to their children about sex education in school, offering tips on how to talk to children about these issues. The first section presents pointers from the "Talking with Kids" campaign: start early; initiate conversations; talk about sex and relationships; create an open…

  13. Educator's Guide to the National Aquarium in Baltimore.

    ERIC Educational Resources Information Center

    Chase, Valerie; And Others

    This guide is designed for educators planning trips to the National Aquarium in Baltimore. The first part provides tips on organizing a school visit and information on the aquarium lobby and exhibits. These exhibits are: (1) Maryland: Mountains to the Sea; (2) Surviving through Adaptation; (3) North Atlantic to the Pacific; (4) South American Rain…

  14. Food Service Management. Second Edition. Answer Book/Teacher's Guide. Second Edition.

    ERIC Educational Resources Information Center

    Hatchett, Melvin S.; Zelade, Richard

    This document contains a student assignment book with 22 assignments for a course in food service management and a teacher's guide with answers to the assignments and tips on presenting the lessons to which they pertain. The assignments cover the following topics: career opportunities; entering the food service industry; classifications of…

  15. A Guide to Reading Tips for Parents.

    ERIC Educational Resources Information Center

    Department of Education, Washington, DC.

    The No Child Left Behind program changes the federal role in education by asking America's schools to describe their success in terms of what each student accomplishes. The information in this reading guide was developed by the United States Department of Education to assist parents, caregivers, and teachers in understanding the importance of…

  16. The Classroom Teacher's Technology Survival Guide

    ERIC Educational Resources Information Center

    Johnson, Doug

    2012-01-01

    This is a must-have resource for all K-12 teachers and administrators who want to really make the best use of available technologies. Written by Doug Johnson, an expert in educational technology, "The Classroom Teacher's Technology Survival Guide" is replete with practical tips teachers can easily use to engage their students and make their…

  17. News: A Consumer's Guide.

    ERIC Educational Resources Information Center

    Doig, Ivan; Doig, Carol

    A guide to news media, this book describes how to tell when a report is biased; provides tips on spotting hoaxes and public relations ploys in the news; gives standards to judge expert opinion and reliable sources; lists critics and other sources of help for the news consumer; discusses the endless contest among politicians, newsmen, and…

  18. Illinois State Bar Association Law Day Activities Guide. 2001 Edition.

    ERIC Educational Resources Information Center

    Illinois State Bar Association, Springfield.

    These law-related lessons and activities can facilitate participation in a Law Day program. Following an introduction, this activities guide is divided into these sections: "Tips for Teachers" ("What Can a Lawyer Add to the Classroom?"; "So You Have Been Asked to Speak to Kids about the Law"; "A Checklist for…

  19. Jobs and Career Planning. College Bound Guide.

    ERIC Educational Resources Information Center

    Mitchell, Joyce Slayton

    This guide to jobs and career planning begins by stressing that high school curriculum choices add up to college choices, and college choices lead to career possibilities. A section on college planning offers tips on deciding what degree to work towards, and describes unusual careers that are unrelated to college majors. A section on career…

  20. Turbine blade tip clearance measurement using a skewed dual-beam fiber optic sensor

    NASA Astrophysics Data System (ADS)

    Ye, De-chao; Duan, Fa-jie; Guo, Hao-tian; Li, Yangzong; Wang, Kai

    2012-08-01

    Optimization and active control of the tip clearance of turbine blades has been identified as a key to improve fuel efficiency, reduce emission, and increase service life of the engine. However, reliable and real-time tip clearance measurement is difficult due to the adverse environmental conditions that are typically found in a turbine. We describe a dual-beam fiber optic measurement system that can measure the tip timing and tip clearance simultaneously. Because the tip timing information is used to calculate the tip clearance, the method is insensitive to the signal intensity variation caused by fluctuations in environmental conditions such as light source instability, contamination, and blade tip imperfection. The system was calibrated and tested using experimental rotors. The test results indicated a high resolution of 4.5 μm and measurement accuracy of ±20 μm over the rotation speed range of 2000 to 10,000 rpm.

  1. Theoretical investigation for excitation light and fluorescence signal of fiber optical sensor using tapered fiber tip.

    PubMed

    Yuan, Yinquan; Ding, Liyun

    2011-10-24

    For fiber optical sensor made of tapered fiber tip, the effects of the geometrical parameters of tapered tip on two important factors have been investigated. One factor is the intensity of the evanescent wave into fluorescent layer through core-medium interface; the other is the intensity of fluorescence signal transmitted from fluorescent layer to measurement end. A dependence relation of the intensity of fluorescence signal transmitted from fluorescent layer to measurement end upon the geometrical parameters of tapered tip has been obtained. Theoretical results show that the intensity of the evanescent wave into fluorescent layer rises with the decrease of the end diameter of tapered tip, and the increase of the tip length; and the transmitted power of fluorescence signal increases linearly with the increase of the tip length due to the contribution of the side area of tapered tip. © 2011 Optical Society of America

  2. The effect of spaceflight on the gravity-sensing auxin gradient of roots: GFP reporter gene microscopy on orbit

    PubMed Central

    Ferl, Robert J; Paul, Anna-Lisa

    2016-01-01

    Our primary aim was to determine whether gravity has a direct role in establishing the auxin-mediated gravity-sensing system in primary roots. Major plant architectures have long been thought to be guided by gravity, including the directional growth of the primary root via auxin gradients that are then disturbed when roots deviate from the vertical as a gravity sensor. However, experiments on the International Space Station (ISS) now allow physical clarity with regard to any assumptions regarding the role of gravity in establishing fundamental root auxin distributions. We examined the spaceflight green fluorescent protein (GFP)-reporter gene expression in roots of transgenic lines of Arabidopsis thaliana: pDR5r::GFP, pTAA1::TAA1–GFP, pSCR::SCR–GFP to monitor auxin and pARR5::GFP to monitor cytokinin. Plants on the ISS were imaged live with the Light Microscopy Module (LMM), and compared with control plants imaged on the ground. Preserved spaceflight and ground control plants were examined post flight with confocal microscopy. Plants on orbit, growing in the absence of any physical reference to the terrestrial gravity vector, displayed typically “vertical” distribution of auxin in the primary root. This confirms that the establishment of the auxin-gradient system, the primary guide for gravity signaling in the root, is gravity independent. The cytokinin distribution in the root tip differs between spaceflight and the ground controls, suggesting spaceflight-induced features of root growth may be cytokinin related. The distribution of auxin in the gravity-sensing portion of the root is not dependent on gravity. Spaceflight appears benign to auxin and its role in the development of the primary root tip, whereas spaceflight may influence cytokinin-associated processes. PMID:28725721

  3. Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting.

    PubMed

    Jakobsson, Lars; Franco, Claudio A; Bentley, Katie; Collins, Russell T; Ponsioen, Bas; Aspalter, Irene M; Rosewell, Ian; Busse, Marta; Thurston, Gavin; Medvinsky, Alexander; Schulte-Merker, Stefan; Gerhardt, Holger

    2010-10-01

    Sprouting angiogenesis requires the coordinated behaviour of endothelial cells, regulated by Notch and vascular endothelial growth factor receptor (VEGFR) signalling. Here, we use computational modelling and genetic mosaic sprouting assays in vitro and in vivo to investigate the regulation and dynamics of endothelial cells during tip cell selection. We find that endothelial cells compete for the tip cell position through relative levels of Vegfr1 and Vegfr2, demonstrating a biological role for differential Vegfr regulation in individual endothelial cells. Differential Vegfr levels affect tip selection only in the presence of a functional Notch system by modulating the expression of the ligand Dll4. Time-lapse microscopy imaging of mosaic sprouts identifies dynamic position shuffling of tip and stalk cells in vitro and in vivo, indicating that the VEGFR-Dll4-Notch signalling circuit is constantly re-evaluated as cells meet new neighbours. The regular exchange of the leading tip cell raises novel implications for the concept of guided angiogenic sprouting.

  4. Experimental quiet engine program

    NASA Technical Reports Server (NTRS)

    Cornell, W. G.

    1975-01-01

    Full-scale low-tip-speed fans, a full-scale high-tip-speed fan, scale model versions of fans, and two full-scale high-bypass-ratio turbofan engines, were designed, fabricated, tested, and evaluated. Turbine noise suppression was investigated. Preliminary design studies of flight propulsion system concepts were used in application studies to determine acoustic-economic tradeoffs. Salient results are as follows: tradeoff evaluation of fan tip speed and blade loading; systematic data on source noise characteristics and suppression effectiveness; documentation of high- and low-fan-speed aerodynamic and acoustic technology; aerodynamic and acoustic evaluation of acoustic treatment configurations, casing tip bleed, serrated and variable pitch rotor blades, leaned outlet guide vanes, slotted tip casings, rotor blade shape modifications, and inlet noise suppression; systematic evaluation of aerodynamic and acoustic effects; flyover noise projections of engine test data; turbine noise suppression technology development; and tradeoff evaluation of preliminary design high-fan-speed and low-fan-speed flight engines.

  5. Energy Saver: Tips on Saving Energy and Money in Your Home

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Casey, Allison L

    This guide shows you how easy it is to reduce your energy use at home and on the road. You'll find quick tips you can use to start saving today, as well as information on larger projects that will help save you money over the long term. Find even more information about saving money and energy at home by visiting our website, EnergySaver.gov.

  6. 3. Light tower and fog signal house, view northeast, west ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Light tower and fog signal house, view northeast, west and south sides - Great Duck Island Light Station, At southern tip of Great Duck Island southeast of Bass Harbor & northeast of Frenchboro, Frenchboro, Hancock County, ME

  7. Diode laser for endodontic treatment: investigations of light distribution and disinfection efficiency

    NASA Astrophysics Data System (ADS)

    Stock, Karl; Graser, Rainer; Udart, Martin; Kienle, Alwin; Hibst, Raimund

    2011-03-01

    Diode lasers are used in dentistry mainly for oral surgery and disinfection of root canals in endodontic treatment. The purpose of this study was to investigate and to improve the laser induced bacteria inactivation in endodontic treatment. An essential prerequisite of the optimization of the irradiation process and device is the knowledge about the determinative factors of bacteria killing: light intensity? light dosis? temperature? In order to find out whether high power NIR laser bacterial killing is caused by a photochemical or a photothermal process we heated bacteria suspensions of E. coli K12 by a water bath and by a diode laser (940 nm) with the same temporal temperature course. Furthermore, bacteria suspensions were irradiated while the temperature was fixed by ice water. Killing of bacteria was measured via fluorescence labeling. In order to optimize the irradiation of the root canal, we designed special fiber tips with radial light emission characteristic by optical ray tracing simulations. Also, we calculated the resulting light distribution in dentin by voxelbased Monte Carlo simulations. Furthermore, we irradiated root canals of extracted human teeth using different fiber tip geometries and measured the resulting light and heat distribution by CCD-camera and thermography. Comparison of killing rates between laser and water based heating shows no significant differences, and irradiation of ice cooled suspensions has no substantial killing effect. Thus, the most important parameter for bacterial killing is the maximum temperature. Irradiation of root canals using fiber tips with radial light emission results in a more defined irradiated area with minor irradiation of the apex and higher intensity and therefore higher temperature increase on root canal surface. In conclusion, our experiments show that at least for E. coli bacteria inactivation by NIR laser irradiation is solely based on a thermal process and that heat distribution in root canal can be significantly improved by specially designed fiber tips.

  8. Localization of needle tip with color doppler during pericardiocentesis: In vitro validation and initial clinical application

    NASA Technical Reports Server (NTRS)

    Armstrong, G.; Cardon, L.; Vilkomerson, D.; Lipson, D.; Wong, J.; Rodriguez, L. L.; Thomas, J. D.; Griffin, B. P.

    2001-01-01

    This study evaluates a new device that uses color Doppler ultrasonography to enable real-time image guidance of the aspirating needle, which has not been possible until now. The ColorMark device (EchoCath Inc, Princeton, NJ) induces high-frequency, low-amplitude vibrations in the needle to enable localization with color Doppler. We studied this technique in 25 consecutive patients undergoing pericardiocentesis, and in vitro, in a urethane phantom with which the accuracy of color Doppler localization of the needle tip was compared with that obtained by direct measurement. Tip localization was excellent in vitro; errors axial to the ultrasound beam (velocity Doppler -0.13 +/- 0.90 mm, power Doppler -0.05 +/- 1.7 mm) were less than lateral errors (velocity -0.36 +/- 1.8 mm, power -0.02 +/- 2.8 mm). In 18 of 25 patients, the needle was identified and guided into the pericardial space with the ColorMark technique, and it allowed successful, uncomplicated drainage of fluid. Initial failures were the result of incorrect settings on the echocardiographic machine and inappropriate combinations of the needle puncture site and imaging window. This study demonstrates a novel color Doppler technique that is highly accurate at localizing a needle tip. The technique is feasible for guiding pericardiocentesis. Further clinical validation of this technique is required.

  9. Improving needle tip identification during ultrasound-guided procedures in anaesthetic practice.

    PubMed

    Scholten, H J; Pourtaherian, A; Mihajlovic, N; Korsten, H H M; A Bouwman, R

    2017-07-01

    Ultrasound guidance is becoming standard practice for needle-based interventions in anaesthetic practice, such as vascular access and peripheral nerve blocks. However, difficulties in aligning the needle and the transducer can lead to incorrect identification of the needle tip, possibly damaging structures not visible on the ultrasound screen. Additional techniques specifically developed to aid alignment of needle and probe or identification of the needle tip are now available. In this scoping review, advantages and limitations of the following categories of those solutions are presented: needle guides; alterations to needle or needle tip; three- and four-dimensional ultrasound; magnetism, electromagnetic or GPS systems; optical tracking; augmented (virtual) reality; robotic assistance; and automated (computerised) needle detection. Most evidence originates from phantom studies, case reports and series, with few randomised clinical trials. Improved first-pass success and reduced performance time are the most frequently cited benefits, whereas the need for additional and often expensive hardware is the greatest limitation to widespread adoption. Novice ultrasound users seem to benefit most and great potential lies in education. Future research should focus on reporting relevant clinical parameters to learn which technique will benefit patients most in terms of success and safety. © 2017 The Association of Anaesthetists of Great Britain and Ireland.

  10. Laser-only Adaptive Optics Achieves Significant Image Quality Gains Compared to Seeing-limited Observations over the Entire Sky

    NASA Astrophysics Data System (ADS)

    Howard, Ward S.; Law, Nicholas M.; Ziegler, Carl A.; Baranec, Christoph; Riddle, Reed

    2018-02-01

    Adaptive optics laser guide-star systems perform atmospheric correction of stellar wavefronts in two parts: stellar tip-tilt and high-spatial-order laser correction. The requirement of a sufficiently bright guide star in the field-of-view to correct tip-tilt limits sky coverage. In this paper, we show an improvement to effective seeing without the need for nearby bright stars, enabling full sky coverage by performing only laser-assisted wavefront correction. We used Robo-AO, the first robotic AO system, to comprehensively demonstrate this laser-only correction. We analyze observations from four years of efficient robotic operation covering 15000 targets and 42000 observations, each realizing different seeing conditions. Using an autoguider (or a post-processing software equivalent) and the laser to improve effective seeing independent of the brightness of a target, Robo-AO observations show a 39% ± 19% improvement to effective FWHM, without any tip-tilt correction. We also demonstrate that 50% encircled energy performance without tip-tilt correction remains comparable to diffraction-limited, standard Robo-AO performance. Faint-target science programs primarily limited by 50% encircled energy (e.g., those employing integral field spectrographs placed behind the AO system) may see significant benefits to sky coverage from employing laser-only AO.

  11. BETTER DUCT SYSTEMS FOR HOME HEATING AND COOLING.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    ANDREWS,J.

    This is a series of six guides intended to provide a working knowledge of residential heating and cooling duct systems, an understanding of the major issues concerning efficiency, comfort, health, and safety, and practical tips on installation and repair of duct systems. These guides are intended for use by contractors, system designers, advanced technicians, and other HVAC professionals. The first two guides are also intended to be accessible to the general reader.

  12. Light curing in orthodontics; should we be concerned?

    PubMed

    McCusker, Neil; Lee, Siu Man; Robinson, Stephen; Patel, Naresh; Sandy, Jonathan R; Ireland, Anthony J

    2013-06-01

    Light cured materials are increasingly used in orthodontic clinical practice and concurrent with developments in materials have been developments in light curing unit technology. In recent years the irradiances of these units have increased. The aim of this study was to determine the safe exposure times to both direct and reflected light. The weighted irradiance and safe exposure times of 11 dental curing lights (1 plasma arc, 2 halogen and 8 LED lights) were determined at 6 distances (2-60 cm) from the light guide tip using a spectroradiometer. In addition, using the single most powerful light, the same two parameters were determined for reflected light. This was done at a distance of 10 cm from the reflected light, but during simulated bonding of 8 different orthodontic brackets of three material types, namely stainless steel, ceramic and composite. The results indicate that the LED Fusion lamp had the highest weighted irradiance and the shortest safe exposure time. With this light the maximum safe exposure time without additional eye protection for the patient (at 10 cm), the operator (at 30 cm) and the assistant (at 60 cm) ranged from 2.5 min, 22.1 min and 88.8 min respectively. This indicates a relatively low short term risk during normal operation of dental curing lights. For reflected light at a distance of 10 cm the risk was even lower, but was affected by the material and shape of the orthodontic bracket under test. The short term risks associated with the use of dental curing lights, halogen, LED or plasma, appear to be low, particularly if as is the case adequate safety precautions are employed. The same is true for reflected light from orthodontic brackets during bonding. What is still unclear is the potential long term ocular effects of prolonged exposure to the blue light generated from dental curing lights. Copyright © 2013 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  13. Optical fiber tips for biological applications: From light confinement, biosensing to bioparticles manipulation.

    PubMed

    Paiva, Joana S; Jorge, Pedro A S; Rosa, Carla C; Cunha, João P S

    2018-05-01

    The tip of an optical fiber has been considered an attractive platform in Biology. The simple cleaved end of an optical fiber can be machined, patterned and/or functionalized, acquiring unique properties enabling the exploitation of novel optical phenomena. Prompted by the constant need to measure and manipulate nanoparticles, the invention of the Scanning Near-field Optical Microscopy (SNOM) triggered the optimization and development of novel fiber tip microfabrication methods. In fact, the fiber tip was soon considered a key element in SNOM by confining light to sufficiently small extensions, challenging the diffraction limit. As result and in consequence of the newly proposed "Lab On Tip" concept, several geometries of fiber tips were applied in three main fields: imaging (in Microscopy/Spectroscopy), biosensors and micromanipulation (Optical Fiber Tweezers, OFTs). These are able to exert forces on microparticles, trap and manipulate them for relevant applications, as biomolecules mechanical study or protein aggregates unfolding. This review presents an overview of the main achievements, most impactful studies and limitations of fiber tip-based configurations within the above three fields, along the past 10 years. OFTs could be in future a valuable tool for studying several cellular phenomena such as neurodegeneration caused by abnormal protein fibrils or manipulating organelles within cells. This could contribute to understand the mechanisms of some diseases or biophenomena, as the axonal growth in neurons. To the best of our knowledge, no other review article has so far provided such a broad view. Despite of the limitations, fiber tips have key roles in Biology/Medicine. Copyright © 2018 Elsevier B.V. All rights reserved.

  14. Visualization of fluid turbulence and acoustic cavitation during phacoemulsification.

    PubMed

    Tognetto, Daniele; Sanguinetti, Giorgia; Sirotti, Paolo; Brezar, Edoardo; Ravalico, Giuseppe

    2005-02-01

    To describe a technique for visualizing fluid turbulence and cavitational energy created by ultrasonic phaco tips. University Eye Clinic of Trieste, Trieste, Italy. Generation of cavitational energy by the phaco tip was visualized using an optical test bench comprising several components. The technique uses a telescope system to expand a laser light source into a coherent, collimated beam of light with a diameter of approximately 50.0 mm. The expanded laser beam shines on the test tube containing the tip activated in a medium of water or ophthalmic viscosurgical device (OVD). Two precision optical collimators complete the optical test bench and form the system used to focus data onto a charge-coupled device television camera connected to a recorder. Images of irrigation, irrigation combined with aspiration, irrigation/aspiration, and phacosonication were obtained with the tip immersed in a tube containing water or OVD. Optical image processing enabled acoustic cavitation to be visualized during phacosonication. The system is a possible means of evaluating a single phaco apparatus power setting and comparing phaco machines and techniques.

  15. Augmented Reality-Guided Lumbar Facet Joint Injections.

    PubMed

    Agten, Christoph A; Dennler, Cyrill; Rosskopf, Andrea B; Jaberg, Laurenz; Pfirrmann, Christian W A; Farshad, Mazda

    2018-05-08

    The aim of this study was to assess feasibility and accuracy of augmented reality-guided lumbar facet joint injections. A spine phantom completely embedded in hardened opaque agar with 3 ring markers was built. A 3-dimensional model of the phantom was uploaded to an augmented reality headset (Microsoft HoloLens). Two radiologists independently performed 20 augmented reality-guided and 20 computed tomography (CT)-guided facet joint injections each: for each augmented reality-guided injection, the hologram was manually aligned with the phantom container using the ring markers. The radiologists targeted the virtual facet joint and tried to place the needle tip in the holographic joint space. Computed tomography was performed after each needle placement to document final needle tip position. Time needed from grabbing the needle to final needle placement was measured for each simulated injection. An independent radiologist rated images of all needle placements in a randomized order blinded to modality (augmented reality vs CT) and performer as perfect, acceptable, incorrect, or unsafe. Accuracy and time to place needles were compared between augmented reality-guided and CT-guided facet joint injections. In total, 39/40 (97.5%) of augmented reality-guided needle placements were either perfect or acceptable compared with 40/40 (100%) CT-guided needle placements (P = 0.5). One augmented reality-guided injection missed the facet joint space by 2 mm. No unsafe needle placements occurred. Time to final needle placement was substantially faster with augmented reality guidance (mean 14 ± 6 seconds vs 39 ± 15 seconds, P < 0.001 for both readers). Augmented reality-guided facet joint injections are feasible and accurate without potentially harmful needle placement in an experimental setting.

  16. 2. Oil house, fog signal house and light tower, view ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Oil house, fog signal house and light tower, view southwest, east and north sides - Great Duck Island Light Station, At southern tip of Great Duck Island southeast of Bass Harbor & northeast of Frenchboro, Frenchboro, Hancock County, ME

  17. Rugged fiber optic probe for raman measurement

    DOEpatents

    O'Rourke, Patrick E.; Toole, Jr., William R.; Nave, Stanley E.

    1998-01-01

    An optical probe for conducting light scattering analysis is disclosed. The probe comprises a hollow housing and a probe tip. A fiber assembly made up of a transmitting fiber and a receiving bundle is inserted in the tip. A filter assembly is inserted in the housing and connected to the fiber assembly. A signal line from the light source and to the spectrometer also is connected to the filter assembly and communicates with the fiber assembly. By using a spring-loaded assembly to hold the fiber connectors together with the in-line filters, complex and sensitive alignment procedures are avoided. The close proximity of the filter assembly to the probe tip eliminates or minimizes self-scattering generated by the optical fiber. Also, because the probe can contact the sample directly, sensitive optics can be eliminated.

  18. Shape memory alloy/shape memory polymer tools

    DOEpatents

    Seward, Kirk P.; Krulevitch, Peter A.

    2005-03-29

    Micro-electromechanical tools for minimally invasive techniques including microsurgery. These tools utilize composite shape memory alloy (SMA), shape memory polymer (SMP) and combinations of SMA and SMP to produce catheter distal tips, actuators, etc., which are bistable. Applications for these structures include: 1) a method for reversible fine positioning of a catheter tip, 2) a method for reversible fine positioning of tools or therapeutic catheters by a guide catheter, 3) a method for bending articulation through the body's vasculature, 4) methods for controlled stent delivery, deployment, and repositioning, and 5) catheters with variable modulus, with vibration mode, with inchworm capability, and with articulated tips. These actuators and catheter tips are bistable and are opportune for in vivo usage because the materials are biocompatible and convenient for intravascular use as well as other minimal by invasive techniques.

  19. Guide to School Renovation and Construction: What You Need To Know To Protect Child and Adult Environmental Health.

    ERIC Educational Resources Information Center

    Healthy Schools Network, Inc., Albany, NY.

    This guide presents cautionary tips for protecting children's health during school renovation and construction projects, the New York state laws regarding school renovation and construction, and the steps the laws require to eliminate dangerous conditions for children during these projects. Included is a checklist of uniform safety standards…

  20. A Storytime Year: A Month-to-Month Kit for Preschool Programming.

    ERIC Educational Resources Information Center

    Dailey, Susan M.

    Noting the need for children's librarians, preschool teachers, and storytellers to keep their programs interesting and fresh, this guide is comprised of 48 theme-based units for preschool-level programs in libraries, early childhood settings, or at home. The guide is presented in two parts. Part 1 contains tips for theme-based program planning and…

  1. Flight to Success: A Collection of Lists Created for Today's Business World.

    ERIC Educational Resources Information Center

    Corder, Lloyd E., Comp.

    This guide suggests ways to improve communication skills for those individuals just starting out in the business world. The guide offers advice from an abundance of sources condensed into easy-to-follow lists on the subjects of: (1) dress tips for men and women; (2) introductions; (3) remembering people's names; (4) conversational techniques for…

  2. Real Jobs for Real People. An Employer's Guide to Youth Apprenticeship.

    ERIC Educational Resources Information Center

    Byrne, Sandra; And Others

    Based on the experience of the National Alliance of Business' youth apprenticeship program (the Quality Connection Consortium), this guide offers practical advice on how employers can begin a youth apprenticeship program that will serve their labor needs. It addresses the internal support that a business must generate and gives tips on choosing an…

  3. Parents' Guide to School Indoor Air Quality.

    ERIC Educational Resources Information Center

    Healthy Schools Network, Inc., Albany, NY.

    This parents' guide presents articles on school indoor air pollution, children's health and the symptoms of indoor air pollution, and how schools can improve their air quality. Also included are tips on what to do if the school ignores air quality problems, and some examples of what school districts should be doing to improve their air quality.…

  4. Ultrasound confirmation of central venous catheter position via a right supraclavicular fossa view using a microconvex probe: an observational pilot study.

    PubMed

    Kim, Se-Chan; Heinze, Ingo; Schmiedel, Alexandra; Baumgarten, Georg; Knuefermann, Pascal; Hoeft, Andreas; Weber, Stefan

    2015-01-01

    Visualisation of a central venous catheter (CVC) with ultrasound is restricted to the internal jugular vein (IJV). CVC tip position is confirmed by chest radiography, intracardiac ECG or transoesophageal/transthoracic echocardiography (TEE/TTE). We explored the feasibility, safety and accuracy of a right supraclavicular view for visualisation of the lower superior vena cava (SVC) and the right pulmonary artery (RPA) as an ultrasound landmark for real-time ultrasound-guided CVC tip positioning via the right IJV. Ultrasound was then compared with chest radiography. An observational pilot study. Bonn, University Hospital, Germany. From July to October 2012. Fifty-one patients scheduled for elective surgery. Reasons for exclusion were emergency procedure, thrombosis or small IJV lumen and mechanical obstacle to guidewire advancement. In 48 patients, CVC insertion via the right IJV and progress of the guidewire into the lower SVC were continuously guided by an ultrasound transducer in the right supraclavicular fossa. CVC tip position in lower SVC and tip-to-carina distance were assessed with chest radiography as a reference method and additionally with TEE in cardiothoracic patients. Insertion depth was compared with intracardiac ECG and body-height formula. The guidewire tip was seen in the SVC of all patients. In four patients, the tip was not visible in proximity of the RPA. Chest radiography and TEE confirmed CVC tip position in the lower SVC (zone A). Bland-Altman analysis revealed an average of difference of 1.6 cm for ultrasound versus ECG (95% limit of agreement -2 to 5 cm) and an average of difference of 1 cm for ultrasound versus body-height formula (95% limit of agreement -2 to 4 cm). Ultrasound via a right supraclavicular view is a feasible, well tolerated and accurate approach and should be further explored. Chest radiography confirmed CVC position in the lower SVC.

  5. Light intensity of curved laryngoscope blades in Philadelphia emergency departments.

    PubMed

    Levitan, Richard M; Kelly, John J; Kinkle, William C; Fasano, Charles

    2007-09-01

    Laryngoscopy and tracheal intubation requires laryngeal exposure and illumination. The objective of this study is to assess variation in laryngoscope lights across different emergency departments (EDs). A convenience sample of 3 Mac #4 blade and handle pairs in each of 17 Philadelphia area EDs was tested with a digital light meter to derive the median lux at the distal tip. For each blade tested, we characterized blade design (American, English, or German) and light type (fiber-illuminated versus conventional bulb-on-blade) and measured light-to-tip distance. A total of 50 blades and handle pairs were tested (one ED had only 2 Mac #4 blades). American designs were the most common (38/50), followed by English (6/50) and German (3/50) designs. Three blades had hybrid design features and acrylic light-conducting fibers. Median luminance varied from 11 lux to 5,627 lux. The glass fiber-illuminated blades (n=13) produced greater luminance (median 1,205 lux; interquartile range [IQR] 726 to 2,176 lux) than bulb-on-blade designs (median 689 lux; IQR 290 to 906 lux). German fiber-illuminated blades produced the highest luminance (median 1,937 lux; IQR 1,453 to 3,782 lux). English bulb-on-blade designs produced more luminance (median 915 lux; IQR 745 to 1270 lux) than American (median 689 lux; IQR 269 to 807 lux). German and English blades had shorter light-to-tip distances (median 51 mm and 47 mm, respectively) than American blades (65 mm). Curved laryngoscope blades in different EDs have marked variation in light intensity. The contribution of luminance to laryngoscopy performance warrants investigation.

  6. Fiber optic probe having fibers with endfaces formed for improved coupling efficiency and method using same

    DOEpatents

    O`Rourke, P.E.; Livingston, R.R.

    1995-03-28

    A fiber optic probe is disclosed for detecting scattered light, with transmitting and receiving fibers having slanted ends and bundled together to form a bevel within the tip of the probe. The probe comprises a housing with a transparent window across its tip for protecting the transmitting and receiving fibers held therein. The endfaces of the fibers are slanted, by cutting, polishing and the like, so that they lie in a plane that is not perpendicular to the longitudinal axis of the respective fiber. The fibers are held in the tip of the probe using an epoxy and oriented so that lines normal to the slanted endfaces are divergent with respect to one another. The epoxy, which is positioned substantially between the transmitting and receiving fibers, is tapered so that the transmitting fiber, the epoxy and the receiving fiber form a bevel of not more than 20 degrees. The angled fiber endfaces cause directing of the light cones toward each other, resulting in improved light coupling efficiency. A light absorber, such as carbon black, is contained in the epoxy to reduce crosstalk between the transmitting and receiving fibers. 3 figures.

  7. Fiber optic probe having fibers with endfaces formed for improved coupling efficiency and method using same

    DOEpatents

    O'Rourke, Patrick E.; Livingston, Ronald R.

    1995-01-01

    A fiber optic probe for detecting scattered light, with transmitting and receiving fibers having slanted ends and bundled together to form a bevel within the tip of the probe. The probe comprises a housing with a transparent window across its tip for protecting the transmitting and receiving fibers held therein. The endfaces of the fibers are slanted, by cutting, polishing and the like, so that they lie in a plane that is not perpendicular to the longitudinal axis of the respective fiber. The fibers are held in the tip of the probe using an epoxy and oriented so that lines normal to the slanted endfaces are divergent with respect to one another. The epoxy, which is positioned substantially between the transmitting and receiving fibers, is tapered so that the transmitting fiber, the epoxy and the receiving fiber form a bevel of not more than 20 degrees. The angled fiber endfaces cause directing of the light cones toward each other, resulting in improved light coupling efficiency. A light absorber, such as carbon black, is contained in the epoxy to reduce crosstalk between the transmitting and receiving fibers.

  8. Soldering instrument safety improvements

    DOEpatents

    Kosslow, William J.; Giron, Ronald W.

    1996-01-01

    A safe soldering device includes a retractable heat shield which can be moved between a first position in which the solder tip of the device is exposed for soldering operation and a second position in which the solder tip is covered by the heat shield. Preferably, the heat shield is biased towards the second position and may be locked in the first position for ease of use. When the soldering device is equipped with a vacuum system, the heat shield may serve to guide the flow of gases and heat from the solder tip away from the work area. The heat shield is preferably made of non-heatsinking plastic.

  9. Guide wire entrapment by inferior vena cava filters: an experimental study.

    PubMed

    Rosen, Michael J; Burns, Justin M; Cobb, William S; Jacobs, David G; Heniford, B Todd; Sing, Ronald F

    2005-09-01

    In situ vena cava filters are at risk for complications with the use of J-tipped guide wires. The purpose of this study was to evaluate the impact of two commonly used J-tipped guide wires on the stability of the four most recently released vena cava filters in an in vitro flow model. Four filters (OptEase [F1], Günther Tulip [F2], Vena Tech LP [F3], and Recovery [F4]) were inserted into an in vitro flow model. Two J-tipped guide wires (0.032-inch [GW-1], 0.035-inch [GW-2]) were passed through each filter (n = 50 passes per wire) for a distance of 10 cm. The inserter was blind as to the effects of the wire. The filters were monitored by an independent observer for adverse events occurring between the filters and the guide wires. These were defined as: migrations (>1 cm), change of position (tilt>10 degrees), and entrapment of the wire (unable to remove wire). Descriptive statistics, chi-square, and Fisher's exact test were used (p < 0.05 considered significant). GW-1 resulted in a lower incidence of entrapment, migration, and tilt for all filters compared with GW-2 (F1, p = 0.003; F2, p < 0.0001; F3, p < 0.0001; F4, p = 0.0004). GW-1 resulted in entrapment in 0%, migration in 7.5%, and tilt in 10.5% of insertions. GW-2 resulted in entrapment in 1%, migration in 26.5%, and tilt in 5.5% of insertions. The incidence of adverse events for GW-1 was significantly different compared with all filters (F1, 0%; F2, 46%; F3, 4%; and F4, 22%; p < 0.0001). Similarly, the incidence of adverse events for GW-2 was significantly different when evaluating all filters (F1, 12%; F2, 48%; F3, 22%; F4 60%; p < 0.0001). The smaller-diameter guide wire resulted in a decreased incidence of adverse events for all filters, but there is still risk for complications. Knowledge of potential complications associated with vena cava filters and the postinsertion use of guide wires are essential to avoid potential mishaps.

  10. Plasmonic nanofocusing of light in an integrated silicon photonics platform.

    PubMed

    Desiatov, Boris; Goykhman, Ilya; Levy, Uriel

    2011-07-04

    The capability to focus electromagnetic energy at the nanoscale plays an important role in nanoscinece and nanotechnology. It allows enhancing light matter interactions at the nanoscale with applications related to nonlinear optics, light emission and light detection. It may also be used for enhancing resolution in microscopy, lithography and optical storage systems. Hereby we propose and experimentally demonstrate the nanoscale focusing of surface plasmons by constructing an integrated plasmonic/photonic on chip nanofocusing device in silicon platform. The device was tested directly by measuring the optical intensity along it using a near-field microscope. We found an order of magnitude enhancement of the intensity at the tip's apex. The spot size is estimated to be 50 nm. The demonstrated device may be used as a building block for "lab on a chip" systems and for enhancing light matter interactions at the apex of the tip.

  11. 101 Tips, Traps, and To-Dos for Creating Teams: A Guidebook for School Leaders. Guiding Groups To Become Teams, Facilitating Them To Become High-Performance Teams, and Empowering Them To Become Technology-Based Teams.

    ERIC Educational Resources Information Center

    Bailey, Gerald D.; Ross, Tweed; Bailey, Gwen L.; Lumley, Dan

    Using teams is an effective way to meet the challenges of breaking down teacher isolation, halting curriculum fragmentation, and creating a learning organization. This guide is designed to help school leaders train groups to become teams, guide them to become high-performance teams, and empower them to become technology-based teams. It contains…

  12. Feasibility of real-time magnetic resonance imaging-guided endomyocardial biopsies: An in-vitro study.

    PubMed

    Lossnitzer, Dirk; Seitz, Sebastian A; Krautz, Birgit; Schnackenburg, Bernhard; André, Florian; Korosoglou, Grigorios; Katus, Hugo A; Steen, Henning

    2015-07-26

    To investigate if magnetic resonance (MR)-guided biopsy can improve the performance and safety of such procedures. A novel MR-compatible bioptome was evaluated in a series of in-vitro experiments in a 1.5T magnetic resonance imaging (MRI) system. The bioptome was inserted into explanted porcine and bovine hearts under real-time MR-guidance employing a steady state free precession sequence. The artifact produced by the metal element at the tip and the signal voids caused by the bioptome were visually tracked for navigation and allowed its constant and precise localization. Cardiac structural elements and the target regions for the biopsy were clearly visible. Our method allowed a significantly better spatial visualization of the bioptoms tip compared to conventional X-ray guidance. The specific device design of the bioptome avoided inducible currents and therefore subsequent heating. The novel MR-compatible bioptome provided a superior cardiovascular magnetic resonance (imaging) soft-tissue visualization for MR-guided myocardial biopsies. Not at least the use of MRI guidance for endomyocardial biopsies completely avoided radiation exposure for both patients and interventionalists. MRI-guided endomyocardial biopsies provide a better than conventional X-ray guided navigation and could therefore improve the specificity and reproducibility of cardiac biopsies in future studies.

  13. Electroluminescence of a polythiophene molecular wire suspended between a metallic surface and the tip of a scanning tunneling microscope.

    PubMed

    Reecht, Gaël; Scheurer, Fabrice; Speisser, Virginie; Dappe, Yannick J; Mathevet, Fabrice; Schull, Guillaume

    2014-01-31

    The electroluminescence of a polythiophene wire suspended between a metallic surface and the tip of a scanning tunneling microscope is reported. Under positive sample voltage, the spectral and voltage dependencies of the emitted light are consistent with the fluorescence of the wire junction mediated by localized plasmons. This emission is strongly attenuated for the opposite polarity. Both emission mechanism and polarity dependence are similar to what occurs in organic light emitting diodes (OLED) but at the level of a single molecular wire.

  14. Sun and Sjogren's Syndrome

    MedlinePlus

    ... California, for authoring this Patient Education Sheet. Ultraviolet (UV) radiation emitted from the sun and other light ... autoantibody SSA/or Ro. To avoid reactions to UV light, try the following tips: Protect your skin ...

  15. Impact of Anatomical, Procedural, and Operator Skill Factors on the Success and Duration of Fluoroscopy-Guided Transjugular Intrahepatic Portosystemic Shunt

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marquardt, Steffen, E-mail: marquardt.steffen@mh-hannover.de; Rodt, Thomas, E-mail: rodt.thomas@mh-hannover.de; Rosenthal, Herbert, E-mail: rosenthal.herbert@mh-hannover.de

    PurposeTo assess the impact of anatomical, procedural, and operator skill factors on the success and duration of fluoroscopy-guided transjugular intrahepatic portoystemic shunt following standard operating procedure (SOP).Material and MethodsDuring a 32-month period, 102 patients underwent transjugular intrahepatic portosystemic shunt creation (TIPS) by two interventional radiologists (IR) following our institutional SOP based on fluoroscopy guidance. Both demographic and procedural data were assessed. The duration of the intervention (D{sub Int}) and of the portal vein puncture (D{sub Punct}) was analyzed depending on the skill level of the IR as well as the anatomic or procedural factors.ResultsIn 99 of the 102 patients, successfulmore » TIPS without peri-procedural complications was performed. The mean D{sub Int} (IR1: 77 min; IR2: 51 min, P < 0.005) and the mean D{sub Punct} (IR1: 19 min; IR2: 13 min, P < 0.005) were significantly higher in TIPS performed by IR1 (with 2 years of clinical experience performing TIPS, n = 38) than by IR2 (>10 years of clinical experience performing TIPS, n = 61), (P < 0.005 both, Mann–Whitney U test). D{sub Int} showed a higher correlation with D{sub Punct} for IR2 (R{sup 2} = 0.63) than for IR1 (R{sup 2} = 0.13). There was no significant difference in the D{sub Punct} for both IRs with regard to the success of the wedged portography (P = 0.90), diameter of the portal vein (P = 0.60), central right portal vein length (P = 0.49), or liver function (MELD-Score before the TIPS procedure; P = 0.14).ConclusionTIPS following SOP is safe, fast, and reliable. The only significant factor for shorter D{sub Punct} and D{sub Int} was the clinical experience of the IR. Anatomic variability, successful portography, or liver function did not alter the duration or technical success of TIPS.« less

  16. 2. Fog signal house and light tower, view west southwest, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Fog signal house and light tower, view west southwest, southeast and northeast sides of signal house, east and north sides of tower - Libby Island Light Station, At southern tip of Libby Island at entrance to Machias Bay, Machiasport, Washington County, ME

  17. 1. Light tower and fog signal house, view south southeast, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Light tower and fog signal house, view south southeast, east and north sides of tower, northeast and northwest sides of signal house - Libby Island Light Station, At southern tip of Libby Island at entrance to Machias Bay, Machiasport, Washington County, ME

  18. Thirty Meter Telescope narrow-field infrared adaptive optics system real-time controller prototyping results

    NASA Astrophysics Data System (ADS)

    Smith, Malcolm; Kerley, Dan; Chapin, Edward L.; Dunn, Jennifer; Herriot, Glen; Véran, Jean-Pierre; Boyer, Corinne; Ellerbroek, Brent; Gilles, Luc; Wang, Lianqi

    2016-07-01

    Prototyping and benchmarking was performed for the Real-Time Controller (RTC) of the Narrow Field InfraRed Adaptive Optics System (NFIRAOS). To perform wavefront correction, NFIRAOS utilizes two deformable mirrors (DM) and one tip/tilt stage (TTS). The RTC receives wavefront information from six Laser Guide Star (LGS) Shack- Hartmann WaveFront Sensors (WFS), one high-order Natural Guide Star Pyramid WaveFront Sensor (PWFS) and multiple low-order instrument detectors. The RTC uses this information to determine the commands to send to the wavefront correctors. NFIRAOS is the first light AO system for the Thirty Meter Telescope (TMT). The prototyping was performed using dual-socket high performance Linux servers with the real-time (PREEMPT_RT) patch and demonstrated the viability of a commercial off-the-shelf (COTS) hardware approach to large scale AO reconstruction. In particular, a large custom matrix vector multiplication (MVM) was benchmarked which met the required latency requirements. In addition all major inter-machine communication was verified to be adequate using 10Gb and 40Gb Ethernet. The results of this prototyping has enabled a CPU-based NFIRAOS RTC design to proceed with confidence and that COTS hardware can be used to meet the demanding performance requirements.

  19. Interferometric fiber optic displacement sensor

    DOEpatents

    Farah, J.

    1999-04-06

    A method is presented to produce a change in the optical path length in the gap between two single mode optical fibers proportional to the lateral displacement of either fiber end normal to its axis. This is done with the use of refraction or diffraction at the interface between a guiding and non-guiding media to change the direction of propagation of the light in the gap. A method is also presented for laying a waveguide on a cantilever so that the displacement of the tip of the cantilever produces a proportional path length change in the gap by distancing the waveguide from the neutral axis of the cantilever. The fiber is supported as a cantilever or a waveguide is deposited on a micromachined cantilever and incorporated in an interferometer which is made totally on a silicon substrate with the use of integrated-optic technology. A resonant element in the form of a micro-bridge is incorporated in the ridge waveguide and produces a frequency output which is readily digitizeable and immune to laser frequency noise. Finally, monolithic mechanical means for phase modulation are provided on the same sensor substrate. This is done by vibrating the cantilever or micro-bridge either electrically or optically. 23 figs.

  20. Interferometric fiber optic displacement sensor

    DOEpatents

    Farah, J.

    1995-05-30

    A method is presented to produce a change in the optical path length in the gap between two single mode optical fibers proportional to the lateral displacement of either fiber end normal to its axis. This is done with the use of refraction or diffraction at the interface between a guiding and non-guiding media to change the direction of propagation of the light in the gap. A method is also presented for laying a waveguide on a cantilever so that the displacement of the tip of the cantilever produces a proportional path length change in the gap by distancing the waveguide from the neutral axis of the cantilever. The fiber is supported as a cantilever or a waveguide is deposited on a micromachined cantilever and incorporated in an interferometer which is made totally on a silicon substrate with the use of integrated-optic technology. A resonant element in the form of a micro-bridge is incorporated in the ridge waveguide and produces a frequency output which is readily digitizeable and immune to laser frequency noise. Finally, monolithic mechanical means for phase modulation are provided on the same sensor substrate. This is done by vibrating the cantilever or micro-bridge either electrically or optically. 29 figs.

  1. Interferometric fiber optic displacement sensor

    DOEpatents

    Farah, John

    1995-01-01

    A method is presented to produce a change in the optical path length in the gap between two single mode optical fibers proportional to the lateral displacement of either fiber end normal to its axis. This is done with the use of refraction or diffraction at the interface between a guiding and non-guiding media to change the direction of propagation of the light in the gap. A method is also presented for laying a waveguide on a cantilever so that the displacement of the tip of the cantilever produces a proportional path length change in the gap by distancing the waveguide from the neutral axis of the cantilever. The fiber is supported as a cantilever or a waveguide is deposited on a micromachined cantilever and incorporated in an interferometer which is made totally on a silicon substrate with the use of integrated-optic technology. A resonant element in the form of a micro-bridge is incorporated in the ridge waveguide and produces a frequency output which is readily digitizeable and immune to laser frequency noise. Finally, monolithic mechanical means for phase modulation are provided on the same sensor substrate. This is done by vibrating the cantilever or micro-bridge either electrically or optically.

  2. Interferometric fiber optic displacement sensor

    DOEpatents

    Farah, John

    1999-01-01

    A method is presented to produce a change in the optical path length in the gap between two single mode optical fibers proportional to the lateral displacement of either fiber end normal to its axis. This is done with the use of refraction or diffraction at the interface between a guiding and non-guiding media to change the direction of propagation of the light in the gap. A method is also presented for laying a waveguide on a cantilever so that the displacement of the tip of the cantilever produces a proportional path length change in the gap by distancing the waveguide from the neutral axis of the cantilever. The fiber is supported as a cantilever or a waveguide is deposited on a micromachined cantilever and incorporated in an interferometer which is made totally on a silicon substrate with the use of integrated-optic technology. A resonant element in the form of a micro-bridge is incorporated in the ridge waveguide and produces a frequency output which is readily digitizeable and immune to laser frequency noise. Finally, monolithic mechanical means for phase modulation are provided on the same sensor substrate. This is done by vibrating the cantilever or micro-bridge either electrically or optically.

  3. A large array of high-performance artificial stars using airship-supported small mirrors

    NASA Astrophysics Data System (ADS)

    Content, Robert; Foxwell, Mark; Murray, Graham J.

    2004-10-01

    We propose a practical system that can provide a large number of high performance artificial stars, of the order of a few hundred, using an array of small mirrors on an airship supported platform illuminated from the ground by a laser. Our concept offers several advantages over other guide star schemes: Airborne mirror arrays can furnish tip-tilt information; they also permit a considerable reduction in the total ground-laser power required; high intensity guide stars with very small angular image size are possible; and finally they offer very low scattered parasite laser light. More basic & simpler launch-laser & AO technologies can therefore be employed, with potentially huge cost savings, with potentially significant improvement in the quality of the AO correction. The general platform scheme and suitable lift technologies are also discussed. A novel concept for achieving precise positioning is presented whereby the platform & the lifting vehicle are linked by a tether, the platform having a degree of independent control. Our proposal would employ as the lift vehicle an autonomous high altitude airship of the type currently under widespread development in the commercial sector, for use as hubs for telecommunication networks, mobile telephone relay stations, etc.

  4. Unusual tumour ablations: report of difficult and interesting cases.

    PubMed

    Mauri, Giovanni; Nicosia, Luca; Varano, Gianluca Maria; Shyn, Paul; Sartori, Sergio; Tombesi, Paola; Di Vece, Francesca; Orsi, Franco; Solbiati, Luigi

    2017-01-01

    Image-guided ablations are nowadays applied in the treatment of a wide group of diseases and in different organs and regions, and every day interventional radiologists have to face more difficult and unusual cases of tumour ablation. In the present case review, we report four difficult and unusual cases, reporting some tips and tricks for a successful image-guided treatment.

  5. College Choices Guide for Migrant Students and Parents = Guia de Elecciones de Universidades para Estudiantes Migrantes y sus Padres.

    ERIC Educational Resources Information Center

    Eddy/Northeast Health, Troy, NY.

    This brief guide is a planning outline to help migrant students and parents prepare for, choose, and apply to college. The first section, "Thinking About College," offers specific tips for each grade from 9-12; discusses high school graduation requirements and college admission requirements, using Johnston County (North Carolina) schools and the…

  6. Participating in the Direct Student Loan Program: Tips for Success.

    ERIC Educational Resources Information Center

    Macro International, Inc., Calverton, MD.

    This guide provides information for schools considering whether to participate in the Federal Direct Student Loan Program, and it offers advice on how to plan for and operate the loan program at an individual school. The information in the guide is presented in a way that follows the steps that need to be taken in planning and implementing the…

  7. Hey, Small Spender: An Insider's Guide to Navigating ALA's Chicago Conference on the Cheap

    ERIC Educational Resources Information Center

    School Library Journal, 2009

    2009-01-01

    This article presents an insider's guide to navigating the American Library Association's (ALA) annual conference in Chicago on July 9-15. As for the extracurricular activities, Chicago has a lot to offer. This article provides tips from the arts and entertainment bible "Time Out Chicago" on where to go and what to do (on a limited…

  8. K-12 Resources on the Internet PLUS: Instructor's Supplement. 2nd Edition.

    ERIC Educational Resources Information Center

    Junion-Metz, Gail

    This volume is a supplement to "K-12 Resources on the Internet: An Instructional Guide" and is intended for teaching trainers that prepare Internet workshops in schools and libraries. It includes the following materials: guidelines on how to use this supplement together with the Instructional Guide in preparing a workshop; tips on how to use the…

  9. Counseling Services Resource Guide: An Internet Guide for the North Carolina Community College Counselor To Assist Virtual Learning Students.

    ERIC Educational Resources Information Center

    North Carolina Community Coll. System, Raleigh.

    This handbook is intended to assist North Carolina community colleges in enhancing their online counseling services. Based on reviews of 58 community colleges in North Carolina, along with several state, national, and university web sites, and the collective efforts of a statewide committee, this handbook offers: (1) General tips for improving…

  10. Una Guia de Consejos Practicos Sobre la Lectura para los Padres (A Guide to Reading Tips for Parents).

    ERIC Educational Resources Information Center

    Department of Education, Washington, DC.

    The No Child Left Behind program changes the federal role in education by asking America's schools to describe their success in terms of what each student accomplishes. The information in this reading guide, presented in Spanish, was developed by the United States Department of Education to assist parents, caregivers, and teachers in understanding…

  11. A deflectable guiding catheter for real-time MRI-guided interventions.

    PubMed

    Bell, Jamie A; Saikus, Christina E; Ratnayaka, Kanishka; Wu, Vincent; Sonmez, Merdim; Faranesh, Anthony Z; Colyer, Jessica H; Lederman, Robert J; Kocaturk, Ozgur

    2012-04-01

    To design a deflectable guiding catheter that omits long metallic components yet preserves mechanical properties to facilitate therapeutic interventional MRI procedures. The catheter shaft incorporated Kevlar braiding. A 180° deflection was attained with a 5-cm nitinol slotted tube, a nitinol spring, and a Kevlar pull string. We tested three designs: passive, passive incorporating an inductively coupled coil, and active receiver. We characterized mechanical properties, MRI properties, RF induced heating, and in vivo performance in swine. Torque and tip deflection force were satisfactory. Representative procedures included hepatic and azygos vein access, laser cardiac septostomy, and atrial septal defect crossing. Visualization was best in the active configuration, delineating profile and tip orientation. The passive configuration could be used in tandem with an active guidewire to overcome its limited conspicuity. There was no RF-induced heating in all configurations under expected use conditions in vitro and in vivo. Kevlar and short nitinol component substitutions preserved mechanical properties. The active design offered the best visibility and usability but reintroduced metal conductors. We describe versatile deflectable guiding catheters with a 0.057" lumen for interventional MRI catheterization. Implementations are feasible using active, inductive, and passive visualization strategies to suit application requirements. Copyright © 2011 Wiley Periodicals, Inc.

  12. Long-distance transmission of light in a scintillator-based radiation detector

    DOEpatents

    Dowell, Jonathan L.; Talbott, Dale V.; Hehlen, Markus P.

    2017-07-11

    Scintillator-based radiation detectors capable of transmitting light indicating the presence of radiation for long distances are disclosed herein. A radiation detector can include a scintillator layer and a light-guide layer. The scintillator layer is configured to produce light upon receiving incident radiation. The light-guide layer is configured to receive light produced by the scintillator layer and either propagate the received light through the radiation detector or absorb the received light and emit light, through fluorescence, that is propagated through the radiation detector. A radiation detector can also include an outer layer partially surrounding the scintillator layer and light-guide layer. The index of refraction of the light-guide layer can be greater than the index of refraction of adjacent layers.

  13. Percolation simulation of laser-guided electrical discharges.

    PubMed

    Sasaki, Akira; Kishimoto, Yasuaki; Takahashi, Eiichi; Kato, Susumu; Fujii, Takashi; Kanazawa, Seiji

    2010-08-13

    A three-dimensional simulation of laser-guided discharges based on percolation is presented. The model includes both local growth of a streamer due to the enhanced electric field at the streamer's tip and propagation of a leader by remote ionization such as that caused by runaway electrons. The stochastic behavior of the discharge through a preformed plasma channel is reproduced by the calculation, which shows complex path with detouring and bifurcation. The probability of guiding is investigated with respect to the ionized, conductive fraction along the channel.

  14. Technical tips to perform safe and effective ultrasound guided steroid joint injections in children.

    PubMed

    Parra, Dimitri A

    2015-01-01

    The aim of this article is to describe the technique used to perform ultrasound guided steroid joint injections in children in a group of joints that can be injected using ultrasound as the only image guidance modality. The technique is described and didactic figures are provided to illustrate key technical concepts. It is very important to be familiar with the sonographic appearance of the pediatric joints and the developing bone when performing ultrasound-guided joint injections in children.

  15. Top Tips for Senior Leaders in Schools and Colleges: How to Provide Meaningful Experience of the World of Work for Young People as Part of 16 to 19 Study Programmes

    ERIC Educational Resources Information Center

    National Foundation for Educational Research, 2015

    2015-01-01

    A core part of 16 to 19 study programmes is the provision of work experience for all young people. It is increasingly recognised that young people need to develop their employability skills, alongside qualifications, in preparation for the world of work and securing a job. This top tips guide offers advice to schools and colleges wishing to…

  16. A comparison of injection pain and postoperative pain of two intraosseous anesthetic techniques.

    PubMed

    Gallatin, Juliane; Nusstein, John; Reader, Al; Beck, Mike; Weaver, Joel

    2003-01-01

    The purpose of this prospective, randomized, blinded study was to compare injection pain and postoperative pain of an apical primary X-Tip intraosseous technique to a coronal primary Stabident intraosseous technique in mandibular first molars. Using a repeated-measures design, 41 subjects randomly received 2 primary intraosseous injections at 2 separate appointments. Using a site distal to the mandibular first molar for both injections, the subjects received 1.8 mL of 2% lidocaine with 1: 100,000 epinephrine administered with the X-Tip system using an apical location in alveolar mucosa or 1.8 mL of 2% lidocaine with 1: 100,000 epinephrine administered with the Stabident system using a coronal location in attached gingiva. The pain of infiltration, perforation, needle insertion, solution deposition, mock or actual guide sleeve removal and postoperative pain were recorded on a Heft-Parker visual analogue scale (VAS) scale for the 2 intraosseous systems. The results demonstrated that the apical primary X-Tip intraosseous technique was not statistically different (P > .05) from the coronal primary Stabident technique regarding pain ratings of infiltration, perforation, needle insertion, solution deposition, mock or actual guide sleeve removal and postoperative pain (at the time subjective anesthesia wore off). However, on postoperative days 1 through 3, significantly (P < .05) more males experienced postoperative pain with the X-Tip system than with the Stabident system.

  17. A Social Science Guide for Communication on Climate Change

    NASA Astrophysics Data System (ADS)

    St John, C.; Marx, S.; Markowitz, E.

    2014-12-01

    Researchers from the Center for Research on Environmental Decisions (CRED) published "The Psychology of Climate Change Communication: A Guide for Scientists, Journalists, Educators, Political Aides, and the Interested Public" in 2009. This landmark guide provided climate change communicators a synthesis of the social science research that was pertinent to understanding how people think about climate change and how the practice could be improved. In the fall of 2014 this guide will be rereleased, with a new title, and in a partnership between CRED and ecoAmerica. The updated guide addresses how and why Americans respond in certain ways to climate change and explains how communicators can apply best practices to their own work. The guide, which includes research from a range of social science fields including psychology, anthropology, communications, and behavioral economics, is designed to be useful for experienced and novice communicators alike. Included in the guide are strategies to boost engagement, common mistakes to avoid, and best practices that organizations around the world have used to meaningfully engage individuals and groups on climate change. The proposed presentation will provide an overview of the main findings and tips from the 2014 climate change communication guide. It will provide a deeper look at a few of the key points that are crucial for increasing audience engagement with climate change including understanding how identity shapes climate change, how to lead with solutions, and how to bring the impacts of climate change close to home. It will highlight tips for motivating positive behavior change that will lead people down the path toward solutions. Finally, it will address the benefits and challenges associated with producing a communication guide and insight into synthesizing social science research findings into a usable format for a variety of audiences.

  18. 7. Keeper's house, fog signal house and light tower, view ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Keeper's house, fog signal house and light tower, view north northeast, west and south sides of keeper's house and tower, southwest and southeast sides of fog signal house - West Quoddy Head Light Station, At eastern tip of West Quaddy Head, Lubec, Washington County, ME

  19. Numerical study on the mechanisms of the SERS of gold-coated pyramidal tip substrates.

    PubMed

    Li, Rui; Wang, Qiao; Li, Hong; Liu, Kun; Pan, Shi; Zhan, Weishen; Chen, Maodu

    2016-06-29

    In this paper, the physical enhancement mechanisms of the surface-enhanced Raman scattering (SERS) of pyramidal tip substrates are studied theoretically. We structure the periodic square-based arrays of adjacent nanometer pyramidal gold-coated tips on silicon. In order to determine the contribution of plasmonic or diffraction effects on the SERS, three-dimensional (3D) numerical simulations are implemented by taking into account the substrate coated with a gold thin film or a perfect electrical conductor thin film. The tip distance, metal coating thickness and incident light polarization angle are also optimized to investigate whether the further SERS signal can be enhanced.

  20. Spatial effect of conical angle on optical-thermal distribution for circumferential photocoagulation

    PubMed Central

    Truong, Van Gia; Park, Suhyun; Tran, Van Nam; Kang, Hyun Wook

    2017-01-01

    A uniformly diffusing applicator can be advantageous for laser treatment of tubular tissue. The current study investigated various conical angles for diffuser tips as a critical factor for achieving radially uniform light emission. A customized goniometer was employed to characterize the spatial uniformity of the light propagation. An ex vivo model was developed to quantitatively compare the temperature development and irreversible tissue coagulation. The 10-mm diffuser tip with angle at 25° achieved a uniform longitudinal intensity profile (i.e., 0.90 ± 0.07) as well as a consistent thermal denaturation on the tissue. The proposed conical angle can be instrumental in determining the uniformity of light distribution for the photothermal treatment of tubular tissue. PMID:29296495

  1. Tips for Buying Exercise Equipment

    MedlinePlus

    ... July 2012 You Might Also Like Dietary Supplements "Free" Trial Offers? Shopping for Home Appliances? Use the EnergyGuide Label Search form Search menu Money & Credit Homes & Mortgages Health & Fitness Healthy Living Treatments & ...

  2. A Hybrid Reality Radiation-free Simulator for Teaching Wire Navigation Skills

    PubMed Central

    Kho, Jenniefer Y.; Johns, Brian D.; Thomas, Geb. W.; Karam, Matthew D.; Marsh, J. Lawrence; Anderson, Donald D.

    2016-01-01

    Objectives Surgical simulation is an increasingly important method to facilitate the acquiring of surgical skills. Simulation can be helpful in developing hip fracture fixation skills because it is a common procedure for which performance can be objectively assessed (i.e., the tip-apex distance). The procedure requires fluoroscopic guidance to drill a wire along an osseous trajectory to a precise position within bone. The objective of this study was to assess the construct validity for a novel radiation-free simulator designed to teach wire navigation skills in hip fracture fixation. Methods Novices (N=30) with limited to no surgical experience in hip fracture fixation and experienced surgeons (N=10) participated. Participants drilled a guide wire in the center-center position of a synthetic femoral head in a hip fracture simulator, using electromagnetic sensors to track the guide wire position. Sensor data were gathered to generate fluoroscopic-like images of the hip and guide wire. Simulator performance of novice and experienced participants was compared to measure construct validity. Results The simulator was able to discriminate the accuracy in guide wire position between novices and experienced surgeons. Experienced surgeons achieved a more accurate tip-apex distance than novices (13 vs 23 mm, respectively, p=0.009). The magnitude of improvement on successive simulator attempts was dependent on level of expertise; tip-apex distance improved significantly in the novice group, while it was unchanged in the experienced group. Conclusions This hybrid reality, radiation-free hip fracture simulator, which combines real-world objects with computer-generated imagery demonstrates construct validity by distinguishing the performance of novices and experienced surgeons. There is a differential effect depending on level of experience, and it could be used as an effective training tool in novice surgeons. PMID:26165262

  3. Radiation Exposure in Transjugular Intrahepatic Portosystemic Shunt Creation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miraglia, Roberto, E-mail: rmiraglia@ismett.edu; Maruzzelli, Luigi, E-mail: lmaruzzelli@ismett.edu; Cortis, Kelvin, E-mail: kelvincortis@ismett.edu

    2016-02-15

    PurposeTransjugular intrahepatic portosystemic shunt (TIPS) creation is considered as being one of the most complex procedures in abdominal interventional radiology. Our aim was twofold: quantification of TIPS-related patient radiation exposure in our center and identification of factors leading to reduced radiation exposure.Materials and methodsThree hundred and forty seven consecutive patients underwent TIPS in our center between 2007 and 2014. Three main procedure categories were identified: Group I (n = 88)—fluoroscopic-guided portal vein targeting, procedure done in an image intensifier-based angiographic system (IIDS); Group II (n = 48)—ultrasound-guided portal vein puncture, procedure done in an IIDS; and Group III (n = 211)—ultrasound-guided portal vein puncture, procedure donemore » in a flat panel detector-based system (FPDS). Radiation exposure (dose-area product [DAP], in Gy cm{sup 2} and fluoroscopy time [FT] in minutes) was retrospectively analyzed.ResultsDAP was significantly higher in Group I (mean ± SD 360 ± 298; median 287; 75th percentile 389 Gy cm{sup 2}) as compared to Group II (217 ± 130; 178; 276 Gy cm{sup 2}; p = 0.002) and Group III (129 ± 117; 70; 150 Gy cm{sup 2}p < 0.001). The difference in DAP between Groups II and III was also significant (p < 0.001). Group I had significantly longer FT (25.78 ± 13.52 min) as compared to Group II (20.45 ± 10.87 min; p = 0.02) and Group III (19.76 ± 13.34; p < 0.001). FT was not significantly different between Groups II and III (p = 0.73).ConclusionsReal-time ultrasound-guided targeting of the portal venous system during TIPS creation results in a significantly lower radiation exposure and reduced FT. Further reduction in radiation exposure can be achieved through the use of modern angiographic units with FPDS.« less

  4. Tips for Energy Savers.

    ERIC Educational Resources Information Center

    Department of Energy, Washington, DC.

    According to 1986 U.S. Department of Energy data, 48% of our residential energy is used to heat and cool our homes, 16% goes for heating water, 12% is used to refrigerators and freezers, and the remaining 24% goes into lighting, cooking, and running appliances. This booklet contains tips for saving energy, including sections on: (1) draft-proof…

  5. Objective-lens-free Fiber-based Position Detection with Nanometer Resolution in a Fiber Optical Trapping System.

    PubMed

    Ti, Chaoyang; Ho-Thanh, Minh-Tri; Wen, Qi; Liu, Yuxiang

    2017-10-13

    Position detection with high accuracy is crucial for force calibration of optical trapping systems. Most existing position detection methods require high-numerical-aperture objective lenses, which are bulky, expensive, and difficult to miniaturize. Here, we report an affordable objective-lens-free, fiber-based position detection scheme with 2 nm spatial resolution and 150 MHz bandwidth. This fiber based detection mechanism enables simultaneous trapping and force measurements in a compact fiber optical tweezers system. In addition, we achieved more reliable signal acquisition with less distortion compared with objective based position detection methods, thanks to the light guiding in optical fibers and small distance between the fiber tips and trapped particle. As a demonstration of the fiber based detection, we used the fiber optical tweezers to apply a force on a cell membrane and simultaneously measure the cellular response.

  6. Radiative control of dark excitons at room temperature by nano-optical antenna-tip Purcell effect

    NASA Astrophysics Data System (ADS)

    Park, Kyoung-Duck; Jiang, Tao; Clark, Genevieve; Xu, Xiaodong; Raschke, Markus B.

    2018-01-01

    Excitons, Coulomb-bound electron-hole pairs, are elementary photo-excitations in semiconductors that can couple to light through radiative relaxation. In contrast, dark excitons (XD) show anti-parallel spin configuration with generally forbidden radiative emission. Because of their long lifetimes, these dark excitons are appealing candidates for quantum computing and optoelectronics. However, optical read-out and control of XD states has remained challenging due to their decoupling from light. Here, we present a tip-enhanced nano-optical approach to induce, switch and programmably modulate the XD emission at room temperature. Using a monolayer transition metal dichalcogenide (TMD) WSe2 on a gold substrate, we demonstrate 6 × 105-fold enhancement in dark exciton photoluminescence quantum yield achieved through coupling of the antenna-tip to the dark exciton out-of-plane optical dipole moment, with a large Purcell factor of ≥2 × 103 of the tip-sample nano-cavity. Our approach provides a facile way to harness excitonic properties in low-dimensional semiconductors offering new strategies for quantum optoelectronics.

  7. Radiative control of dark excitons at room temperature by nano-optical antenna-tip Purcell effect.

    PubMed

    Park, Kyoung-Duck; Jiang, Tao; Clark, Genevieve; Xu, Xiaodong; Raschke, Markus B

    2018-01-01

    Excitons, Coulomb-bound electron-hole pairs, are elementary photo-excitations in semiconductors that can couple to light through radiative relaxation. In contrast, dark excitons (X D ) show anti-parallel spin configuration with generally forbidden radiative emission. Because of their long lifetimes, these dark excitons are appealing candidates for quantum computing and optoelectronics. However, optical read-out and control of X D states has remained challenging due to their decoupling from light. Here, we present a tip-enhanced nano-optical approach to induce, switch and programmably modulate the X D emission at room temperature. Using a monolayer transition metal dichalcogenide (TMD) WSe 2 on a gold substrate, we demonstrate ~6 × 10 5 -fold enhancement in dark exciton photoluminescence quantum yield achieved through coupling of the antenna-tip to the dark exciton out-of-plane optical dipole moment, with a large Purcell factor of ≥2 × 10 3 of the tip-sample nano-cavity. Our approach provides a facile way to harness excitonic properties in low-dimensional semiconductors offering new strategies for quantum optoelectronics.

  8. Actual light deflections in regions of crack tips and their influence on measurements in photomechanics

    NASA Astrophysics Data System (ADS)

    Hecker, Friedrich W.; Pindera, Jerzy T.; Wen, Baicheng

    Crack-tip photomechanics procedures are based on certain simplifying assumptions that are seldom discussed. In a recent paper the theoretical bases of the shadow optical methods of caustics have been analysed and tested using the results obtained by three analytical-experimental procedures, namely classical strain gage techniques, isodynes, and strain-gradient index method. It has been concluded that the straing-radient index method appears to be a suitable tool for analysis of stress states near crack tips and notches and, in particular, for testing the predictive power of the pertinent singular solutions of the linear elastic fracture mechanics and the ranges of their applicability. In the present paper, a more detailed analysis of all results obtained in light deflection experiments allows to quantify the contribution of both involved effects and to determine the distortion of the faces of the investigated plates along their crack planes. The ability of the strain-gradient light bending method to analyse some features of the three-dimensional stress-state is reported. Finally, the presented experimental evidence allows to draw conclusions related to limits of applicability of certain photomechanical measurements near crack tips. An extensive summary of this paper is published in the Proceedings of the Second International Conference on Photomechanics and Speckle Metrology, Vol. 1554A, part of SPIE's 1991 International Symposium on Optical Applied Science and Engineering, 22-26 July 1991, San Diego, CA, USA. 1

  9. Imaging diagnostics of pulsed plasma discharges in saline generated with various sharp pin powered electrodes

    NASA Astrophysics Data System (ADS)

    Asimakoulas, L.; Karim, M. L.; Dostal, L.; Krcma, F.; Graham, W. G.; Field, T. A.

    2016-09-01

    Plasmas formed by 1 ms pulses of between 180 and 300 V applied to sharp pin-like electrodes immersed in saline solution have been imaged with a Photron SA-X2 fast framing camera and an Andor iStar 510 ICCD camera. Stainless steel, Tungsten and Gold electrodes were investigated with tip diameters of 30 μm, 1 μm and < 1 μ m respectively. As previously observed, a vapour layer forms around the electrode prior to plasma ignition. For gold and stainless steel lower voltages were required to minimize electrode damage. Preliminary anlaysis indicates at lower voltages for all tips the fast framing results show that light emission is normally centred on a single small volume, which appears to move about, but remains close to the tip. In the case of Tungsten with higher voltages or longer pulses the tip of the needle can heat up to incandescent temperatures. At higher voltages shock wave fronts appear to be observed as the vapour layer collapses at the end of the voltage pulse. Backlighting and no lighting to observe bubble/vapour layer formation and emission due to plasma formation were employed. Sometimes at higher voltages a thicker vapour layer engulfs the tip and no plasma emission/current is observed.

  10. New Phenomena in High Temperature Nanofriction on Nonmelting Surfaces: NaCl(100)

    NASA Astrophysics Data System (ADS)

    Zykova-Timan, Tatyana; Ceresoli, Davide; Tosatti, Erio

    2006-03-01

    High temperature nanofriction is a difficult and so far unexplored area whwere we made an initial attack by means of simulation. Alkali halide (100) surfaces were chosen as they would not automatically liquefy under a sliding tip, even at temperatures very close to the melting point. We conducted sliding friction molecular dynamics simulations of hard tips on NaCl(100),both in the heavy ploughing, wear-dominated regime, and in the light grazing, wearless regime. Ploughing friction shows for increasing temperature a strong frictional drop near the melting point. Here the tip can be characterized as ``skating'' over the hot solid, its apex surrounded by a local liquid halo, which moves along with the tip as it ploughs on. At the opposite extreme, we find that grazing friction of a lightly pressed flat-ended tip behaves just the other way around. Starting with an initially very weak low temperature frictional force, there is a surge of friction just near the melting point, where the surface is still solid, but not too far from a vibrational instability. This frictional rise can be envisaged as an analog of the celebrated ``peak effect'' found close to Hc2 in the mixed state critical current of type II superconductors.

  11. Optical detection of ultrasound using an apertureless near-field scanning optical microscopy system

    NASA Astrophysics Data System (ADS)

    Ahn, Phillip; Zhang, Zhen; Sun, Cheng; Balogun, Oluwaseyi

    2013-01-01

    Laser ultrasonics techniques are power approaches for non-contact generation and detection of high frequency ultrasound on a local scale. In these techniques, optical diffraction limits the spatial information that can be accessed from a measurement. In order to improve the lateral spatial resolution, we incorporate an apertureless near-field scanning optical microscope (aNSOM) into laser ultrasonics setup for local detection of laser generated ultrasound. The aNSOM technique relies on the measurement of a weak backscattered near-field light intensity resulting from the oblique illumination of a nanoscale probe-tip positioned close to a sample surface. We enhance the optical near-field intensity by coupling light to surface plasmon polaritons (SPPs) on the shaft of an atomic force microscopy (AFM) cantilever. The SPPs propagate down the AFM shaft, localize at the tip apex, and are backscattered to the far-field when the separation distance between the probe tip and the sample surface is comparable to the probe-tip radius. The backscattered near-field intensity is dynamically modulated when an ultrasonic wave arrives at the sample surface leading to a transient change in the tip-sample separation distance. We present experimental results detailing measurement of broadband and narrowband laser generated ultrasound in solids with frequencies reaching up to 180 MHz range.

  12. 1. Keeper's house, small boathouse, and light tower, view east, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Keeper's house, small boathouse, and light tower, view east, west and south sides of keeper's house, west side of boathouse and tower - Great Duck Island Light Station, At southern tip of Great Duck Island southeast of Bass Harbor & northeast of Frenchboro, Frenchboro, Hancock County, ME

  13. Hydrotropism and its interaction with gravitropism in maize roots

    NASA Technical Reports Server (NTRS)

    Takahashi, H.; Scott, T. K.

    1991-01-01

    We have partially characterized root hydrotropism and its interaction with gravitropism in maize (Zea mays L.). Roots of Golden Cross Bantam 70, which require light for orthogravitropism, showed positive hydrotropism; bending upward when placed horizontally below a hydrostimulant (moist cheesecloth) in 85% relative humidity (RH) and in total darkness. However, the light-exposed roots of Golden Cross Bantam 70 or roots of a normal maize cultivar, Burpee Snow Cross, showed positive gravitropism under the same conditions; bending downward when placed horizontally below the hydrostimulant in 85% RH. Light-exposed roots of Golden Cross Bantam 70 placed at 70 degrees below the horizontal plane responded positively hydrotropically, but gravitropism overcame the hydrotropism when the roots were placed at 45 degrees below the horizontal. Roots placed vertically with the tip down in 85% RH bent to the side toward the hydrostimulant in both cultivars, and light conditions did not affect the response. Such vertical roots did not respond when the humidity was maintained near saturation. These results suggest that hydrotropic and gravitropic responses interact with one another depending on the intensity of one or both factors. Removal of the approximately 1.5 millimeter root tip blocked both hydrotropic and gravitropic responses in the two cultivars. However, removal of visible root tip mucilage did not affect hydrotropism or gravitropism in either cultivar.

  14. Inducible growth mode switches influence Valonia rhizoid differentiation.

    PubMed

    Elvira, Paul Rommel; Sekida, Satoko; Okuda, Kazuo

    2013-02-01

    Cell differentiation and cell type commitment are an integral part of plant growth and development. Investigations on how environmental conditions affect the formation of shoots, roots, and rhizoids can help illustrate how plants determine cell fate and overall morphology. In this study, we evaluated the role of substratum and light on rhizoid differentiation in the coenocytic green alga, Valonia aegagropila. Elongating rhizoids displayed varying growth modes and cell shape upon exposure to different substrata and light conditions. It was found that soft substrata and dark incubation promoted rhizoid elongation via tip growth while subsequent exposure to light prevented tip growth and instead induced swelling in the apical region of rhizoids. Swelling was accompanied by the accumulation of protoplasm in the rhizoid tip through expansion of the cell wall and uninhibited cytoplasmic streaming. Subsequent diffuse growth led to the transformation from slender, rod-shaped rhizoids into spherical thallus-like structures that required photosynthesis. Further manipulation of light regimes caused vacillating cell growth redirections. An elongating V. aegagropila rhizoid cell thus appears capable of growth mode switching that is regulated by immediate environmental conditions thereby influencing ultimate cell shape and function. This is the first description of inducible, multiple growth mode shifts in a single intact plant cell that directly impact its differentiation.

  15. Two-photon excited fluorescence from a pseudoisocyanine-attached gold-coated tip via a thin tapered fiber under a weak continuous wave excitation.

    PubMed

    Ren, Fang; Takashima, Hideaki; Tanaka, Yoshito; Fujiwara, Hideki; Sasaki, Keiji

    2013-11-18

    A simple tapered fiber based photonic-plasmonic hybrid nanostructure composed of a thin tapered fiber and a pseudoisocyanine (PIC)-attached Au-coated tip was demonstrated. Using this simple hybrid nanostructure, we succeeded in observing two-photon excited fluorescence from the PIC dye molecules under a weak continuous wave excitation condition. From the results of the tip-fiber distance dependence and excitation polarization dependence, we found that using a thin tapered fiber and an Au-coated tip realized efficient coupling of the incident light (~95%) and LSP excitation at the Au-coated tip, suggesting the possibility of efficiently inducing two-photon excited fluorescence from the PIC dye molecules attached on the Au-coated tip. This simple photonic-plasmonic hybrid system is one of the promising tools for single photon sources, highly efficient plasmonic sensors, and integrated nonlinear plasmonic devices.

  16. Highly sensitive mode mapping of whispering-gallery modes by scanning thermocouple-probe microscopy.

    PubMed

    Klein, Angela E; Schmidt, Carsten; Liebsch, Mattes; Janunts, Norik; Dobynde, Mikhail; Tünnermann, Andreas; Pertsch, Thomas

    2014-03-01

    We propose a method for mapping optical near-fields with the help of a thermocouple scanning-probe microscope tip. As the tip scans the sample surface, its apex is heated by light absorption, generating a thermovoltage. The thermovoltage map represents the intensity distribution of light at the sample surface. The measurement technique has been employed to map optical whispering-gallery modes in fused silica microdisk resonators operating at near-infrared wavelengths. The method could potentially be employed for near-field imaging of a variety of systems in the near-infrared and visible spectral range.

  17. Light transmittance and surface roughness of a feldspathic ceramic CAD-CAM material as a function of different surface treatments.

    PubMed

    Ural, Çağrı; Duran, İbrahim; Evmek, Betül; Kavut, İdris; Cengiz, Seda; Yuzbasioglu, Emir

    2016-07-15

    The aim of the present study was to determine the effect of different surface treatments on light transmission of aesthetic feldspathic ceramics used in CAD-CAM chairside restorations. Forty eight feldspatic ceramic test specimens were prepared from prefabricated CAD-CAM blocks by using a slow speed diamond saw. Test specimens were prepared and divided into 4 groups (n = 12). In the control group, no surface treatments were applied on the feldspathic ceramic surfaces. In the hydrofluoric acid group, the bonding surfaces of feldspathic ceramics were etched with 9.5 % hydrofluoric acid. In the sandblasting group the feldspathic ceramic surfaces were air-abraded with 30-μm alumium oxide (Al2O3) particles and Er:YAG laser was used to irradiate the ceramic surfaces. The incident light power given by the LED device and the transmitted light power through each ceramic sample was registered using a digital LED radiometer device. Each polymerization light had a light guide with 8-mm-diameter tips. Light transmission of feldspathic ceramic samples was determined by placing it on the radiometer and irradiating the specimen for 10 s at the highest setting for each light polymerization. All specimens were coated with gold using a sputter coater and examined under a field emission scanning electron microscope. Surface roughness measurement each group were evaluated with 3D optical surface and tactile profilometers. One-way ANOVA test results revealed that both surface conditioning method significantly affect the light transmittance (F:412.437; p < 0.001) and the surface roughness values (F:16.386; p < 0.001). Al2O3 and Er-YAG laser application reduced the light transmission significantly (p < 0.05). The laser and Al2O3 applications reduced the light transmission of 1.5 mm thickness feldspathic ceramic material below the value of 400 mW/cm(2) which is critical limit for safe polymerization.

  18. Raising Multiple Birth Children: A Parents' Survival Guide. Surviving the First Three Years of Twins & Supertwins.

    ERIC Educational Resources Information Center

    Laut, William; Laut, Sheila

    Although the rate of multiple births has skyrocketed, many parents of twins and triplets find that they are struggling on their own to cope with the emotional, psychological, and financial pressures of parenting more than one baby. This book is a survival guide for parents of multiples, containing a compendium of tips and techniques collected from…

  19. Tips for Talking to Children and Youth after Traumatic Events: A Guide for Parents and Educators

    ERIC Educational Resources Information Center

    Substance Abuse and Mental Health Services Administration, 2007

    2007-01-01

    Children respond to trauma in many different ways. Some may have reactions very soon after the event; others may do fine for weeks or months, and then begin to show troubling behavior. Knowing the signs that are common at different ages can help parents and teachers recognize problems and respond appropriately. This guide lists common symptoms of…

  20. Too Old for This, Too Young for That! Your Survival Guide for the Middle-School Years.

    ERIC Educational Resources Information Center

    Mosatche, Harriet S.; Unger, Karen

    Noting that the early adolescent years may be likened to a roller coaster, often unpredictable but exciting and filled with possibility, this book is designed as a survival guide for students in grades 6 through 9 and addresses questions about the new choices and challenges ahead. The seven chapters or "survival tips" are: (1) "Get Used to Your…

  1. A Guide to Inservice Educators: Tips for Obtaining and Utilizing Consultants in Public Schools. Teacher Education Forum Series. Vol. 2, No. 10.

    ERIC Educational Resources Information Center

    Harty, Harold; Bonwit, Toby

    This guide to inservice education is designed to help people in school systems (teachers, administrators, counselors, evaluators, and paraprofessionals) with the selection and use of the skills and knowledge of those university faculty committed to inservice education. Consultants are listed who are willing to serve as leaders of workshops,…

  2. Teaching the Internet to Library Staff and Users: 10 Ready-To-Go Workshops That Work. Neal-Schuman NetGuide Series.

    ERIC Educational Resources Information Center

    Hollands, William D.

    This guide features 10 customizable, ready-to-run workshops for librarians wishing to establish or refine ongoing Internet training for staff members or patrons. Each workshop in the book includes an introduction, an objective, a timed lesson plan, tips, a sample script, and reproducible handouts. In order to provide for the variety of settings…

  3. Emergency coronary angioplasty with stenting using Cordis® diagnostic coronary catheters when there is difficulty in engaging guide catheters and bench evaluation of diagnostic and guide catheters.

    PubMed

    Arokiaraj, Mark Christopher

    2018-02-01

    Difficulty in engaging with guide catheters is not uncommon in acute emergencies. We aimed to evaluate the use of Cordis ® INFINITI diagnostic catheters to perform angioplasty in patients in whom the coronaries cannot be engaged using standard guide catheters. In 34 cases of acute coronary syndrome, when difficulty in engagement with two standard guide catheters was encountered with reasonable manipulations, angioplasty was performed using diagnostic catheters. In total, 40 stents were placed by this technique. Pushability and trackability, distal tip flexion and three-point bending tests were performed to evaluate the performance of the guide and diagnostic catheters. Angioplasty was performed easily in a setting where it would have been very difficult to perform. Coronary dissection occurred in one patient, treated by a stent. The stent and dilatation balloons were easily passed through the diagnostic catheters. Pressure tracings were clearly preserved with certain stent delivery systems, and at angioplasty, although there was slightly reduced opacification of the respective artery, the coronary anatomy was sufficiently visualized to perform angioplasty. No periprocedural target lesion complications were seen in any cases. Pushability and trackability tests showed good force transmission along a tortuous path with diagnostic catheters, and balanced force-displacement curves from three-point bending tests and distal tip softness tests. Angioplasty with stenting can be performed safely through 6F Cordis ® infiniti diagnostic catheters when difficulty in engaging guide catheters is encountered. Copyright © 2018 Sociedade Portuguesa de Cardiologia. Publicado por Elsevier España, S.L.U. All rights reserved.

  4. Redesigned rotor for a highly loaded, 1800 ft/sec tip speed compressor fan stage 1: Aerodynamic and mechanical design

    NASA Technical Reports Server (NTRS)

    Halle, J. E.; Ruschak, J. T.

    1975-01-01

    A highly loaded, high tip-speed fan rotor was designed with multiple-circular-arc airfoil sections as a replacement for a marginally successful rotor which had precompression airfoil sections. The substitution of airfoil sections was the only aerodynamic change. Structural design of the redesigned rotor blade was guided by successful experience with the original blade. Calculated stress levels and stability parameters for the redesigned rotor are within limits demonstrated in tests of the original rotor.

  5. Transjugular Intrahepatic Portosystemic Shunt Creation in Budd-Chiari Syndrome: Percutaneous Ultrasound-Guided Direct Simultaneous Puncture of the Portal Vein and Vena Cava

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Boyvat, Fatih, E-mail: boyvatf@yahoo.com; Aytekin, Cueneyt; Harman, Ali

    Budd-Chiari syndrome (BCS) is an uncommon disorder that can be life-threatening, depending on the degree of hepatic venous outflow obstruction. Transjugular intrahepatic portosystemic shunt (TIPS) provides decompression of the congested liver but the hepatic vein obstruction makes the procedure more difficult. We describe a modified method that involved a single percutaneous puncture of the portal vein and inferior vena cava simultaneously for TIPS creation in a patient with BCS.

  6. Kidney Transplantation: MedlinePlus Health Topic

    MedlinePlus

    ... as They Affect Physical Fitness: A Physical Therapist's Point of View (National Kidney Foundation) Solitary Kidney (National Institute of Diabetes and Digestive and Kidney Diseases) Travel Tips: A Guide for Kidney Patients (National Kidney ...

  7. Sample transportation management plans and templates.

    DOT National Transportation Integrated Search

    2010-08-01

    This Guide consisting of samples, templates, and tips is designed to help transportation agencies with the : development and implementation of their own Transportation Management Plans (TMPs). Understanding : the work zone impacts is critical to deve...

  8. Travel Tips: A Guide for Kidney Patients

    MedlinePlus

    ... enough supplies for the length of the trip, plus some extra supplies in case of problems. It ... tablets and appropriate snacks, such as low-potassium juice boxes or hard candy, to treat low blood ...

  9. On the feasibility of MRI-guided navigation to demarcate breast cancer for breast-conserving surgery.

    PubMed

    Alderliesten, Tanja; Loo, Claudette; Paape, Anita; Muller, Sara; Rutgers, Emiel; Peeters, Marie-Jeanne Vrancken; Gilhuijs, Kenneth

    2010-06-01

    The aim of this study was to investigate the feasibility of image-guided navigation approaches to demarcate breast cancer on the basis of preacquired magnetic resonance (MR) imaging in supine patient orientation. Strategies were examined to minimize the uncertainty in the instrument-tip position, based on the hypothesis that the release of instrument pressure returns the breast tissue to its predeformed state. For this purpose, four sources of uncertainty were taken into account: (1) U(ligaments): Uncertainty in the reproducibility of the internal mammary gland geometry during repeat patient setup in supine orientation; (2) U(r_breathing): Residual uncertainty in registration of the breast after compensation for breathing motion using an external marker; (3) U(reconstruction): Uncertainty in the reconstructed location of the tip of the needle using an optical image-navigation system (phantom experiments, n = 50); and (4) U(deformation): Uncertainty in displacement of breast tumors due to needle-induced tissue deformations (patients, n = 21). A Monte Carlo study was performed to establish the 95% confidence interval (CI) of the combined uncertainties. This region of uncertainty was subsequently visualized around the reconstructed needle tip as an additional navigational aid in the preacquired MR images. Validation of the system was performed in five healthy volunteers (localization of skin markers only) and in two patients. In the patients, the navigation system was used to monitor ultrasound-guided radioactive seed localization of breast cancer. Nearest distances between the needle tip and the tumor boundary in the ultrasound images were compared to those in the concurrently reconstructed MR images. Both U(reconstruction) and U(deformation) were normally distributed with 0.1 +/- 1.2 mm (mean +/- 1 SD) and 0.1 +/- 0.8 mm, respectively. Taking prior estimates for U(ligaments) (0.0 +/- 1.5 mm) and U(r_breathing) (-0.1 +/- 0.6 mm) into account, the combined impact resulted in 3.9 mm uncertainty in the position of the needle tip (95% CI) after release of pressure. The volunteer study showed a targeting accuracy comparable to that in the phantom experiments: 2.9 +/- 1.3 versus 2.7 +/- 1.1 mm, respectively. In the patient feasibility study, the deviations were within the 3.9 mm CI. Image-guided navigation to demarcate breast cancer on the basis of preacquired MR images in supine orientation appears feasible if patient breathing is tracked during the navigation procedure, positional uncertainty is visualized and pressure on the localization instrument is released prior to verification of its position.

  10. Twelve Tips for teaching medical professionalism at all levels of medical education.

    PubMed

    Al-Eraky, Mohamed Mostafa

    2015-01-01

    Review of studies published in medical education journals over the last decade reveals that teaching medical professionalism is essential, yet challenging. According to a recent Best Evidence in Medical Education (BEME) guide, there is no consensus on a theoretical or practical model to integrate the teaching of professionalism into medical education. The aim of this article is to outline a practical manual for teaching professionalism at all levels of medical education. Drawing from research literature and author's experience, Twelve Tips are listed and organised in four clusters with relevance to (1) the context, (2) the teachers, (3) the curriculum, and (4) the networking. With a better understanding of the guiding educational principles for teaching medical professionalism, medical educators will be able to teach one of the most challenging constructs in medical education.

  11. STM-induced light emission enhanced by weakly coupled organic ad-layers

    NASA Astrophysics Data System (ADS)

    Cottin, M. C.; Ekici, E.; Bobisch, C. A.

    2018-03-01

    We analyze the light emission induced by the tunneling current flowing in a scanning tunneling microscopy experiment. In particular, we study the influence of organic ad-layers on the light emission on the initial monolayer of bismuth (Bi) on Cu(111) in comparison to the well-known case of organic ad-layers on Ag(111). On the Bi/Cu(111)-surface, we find that the scanning tunneling microscopy-induced light emission is considerably enhanced if an organic layer, e.g., the fullerene C60 or the perylene derivate perylene-tetracarboxylic-dianhydride, is introduced into the tip-sample junction. The enhancement can be correlated with a peculiarly weak interaction between the adsorbed molecules and the underlying Bi/Cu(111) substrate as compared to the Ag(111) substrate. This allows us to efficiently enhance and tune the coupling of the tunneling current to localized excitations of the tip-sample junction, which in turn couple to radiative decay channels.

  12. Holographic studies of shock waves within transonic fan rotors

    NASA Technical Reports Server (NTRS)

    Benser, W. A.; Bailey, E. E.; Gelder, T. F.

    1974-01-01

    NASA has funded two separate contracts to apply pulsed laser holographic interferometry to the detection of shock patterns in the outer span regions of high tip speed transonic rotors. The first holographic approach used ruby laser light reflected from a portion of the centerbody just ahead of the rotor. These holograms showed the bow wave patterns upstream of the rotor and the shock patterns just inside the blade row near the tip. The second holographic approach, on a different rotor, used light transmitted diagonally across the inlet annulus past the centerbody. This approach gave a more extensive view of the region bounded by the blade leading and trailing edges, by the part span shroud and by the blade tip. These holograms showed the passage shock emanating from the blade leading edge and a moderately strong conical shock originating at the intersection of the part span shroud leading edge and the blade suction surface.

  13. Hyperspectral imaging for detection of black tip damage in wheat kernels

    NASA Astrophysics Data System (ADS)

    Delwiche, Stephen R.; Yang, I.-Chang; Kim, Moon S.

    2009-05-01

    A feasibility study was conducted on the use of hyperspectral imaging to differentiate sound wheat kernels from those with the fungal condition called black point or black tip. Individual kernels of hard red spring wheat were loaded in indented slots on a blackened machined aluminum plate. Damage conditions, determined by official (USDA) inspection, were either sound (no damage) or damaged by the black tip condition alone. Hyperspectral imaging was separately performed under modes of reflectance from white light illumination and fluorescence from UV light (~380 nm) illumination. By cursory inspection of wavelength images, one fluorescence wavelength (531 nm) was selected for image processing and classification analysis. Results indicated that with this one wavelength alone, classification accuracy can be as high as 95% when kernels are oriented with their dorsal side toward the camera. It is suggested that improvement in classification can be made through the inclusion of multiple wavelength images.

  14. Morphology of Er:YAG-laser-treated root surfaces

    NASA Astrophysics Data System (ADS)

    Keller, Ulrich; Stock, Karl; Hibst, Raimund

    1997-12-01

    From previous studies it could be demonstrated that an efficient ablation of dental calculus is possible using an Er:YAG laser with a special contact fiber tip. After improving of the design and the efficiency of light transmission of the contact tip laser treated tooth root surfaces were investigated due to morphological changes in comparison to conventional root scaling and planing. Surface modifications were observed histologically under the light microscope and by means of a Scanning Electron Microscope. During laser treatment the intrapulpal temperature increase was measured. The results show that the improved contact tip a microstructured surface can be generated, which shows no signs of thermal effects even when a laser pulse repetition rate of 15 Hz was used. Temperature increase was limited to 4 K at a repetition rate of 10 Hz and to 5.5 K at a repetition rate of 15 Hz.

  15. Ultrasound-guided suprascapular nerve block: a correlation with fluoroscopic and cadaveric findings.

    PubMed

    Peng, Philip W H; Wiley, Michael J; Liang, James; Bellingham, Geoff A

    2010-02-01

    Previous work on the ultrasound-guided injection technique and the sonoanatomy of the suprascapular region relevant to the suprascapular nerve (SSN) block suggested that the ultrasound scan showed the presence of the suprascapular notch and transverse ligament. The intended target of the ultrasound-guided injection was the notch. The objective of this case report and the subsequent cadaver dissection findings is to reassess the interpretation of the ultrasound images when locating structures for SSN block. A 45-yr-old man with chronic shoulder pain received an ultrasound-guided SSN block using the suprascapular notch as the intended target. The position of the needle was verified by fluoroscopy, which showed the tip of the needle well outside the suprascapular notch. Similar ultrasound-guided SSN blocks were performed in two cadavers. Dissections were performed which showed that the needle tips were not at the suprascapular notch but, more accurately, were close to the SSN but at the floor of the suprascapular fossa between the suprascapular and spinoglenoid notch. Our fluoroscopic and cadaver dissection findings both suggest that the ultrasound image of the SSN block shown by the well-described technique is actually targeting the nerve on the floor of the suprascapular spine between the suprascapular and spinoglenoid notches rather than the suprascapular notch itself. The structure previously identified as the transverse ligament is actually the fascia layer of the supraspinatus muscle.

  16. Transurethral light delivery for prostate photoacoustic imaging

    NASA Astrophysics Data System (ADS)

    Lediju Bell, Muyinatu A.; Guo, Xiaoyu; Song, Danny Y.; Boctor, Emad M.

    2015-03-01

    Photoacoustic imaging has broad clinical potential to enhance prostate cancer detection and treatment, yet it is challenged by the lack of minimally invasive, deeply penetrating light delivery methods that provide sufficient visualization of targets (e.g., tumors, contrast agents, brachytherapy seeds). We constructed a side-firing fiber prototype for transurethral photoacoustic imaging of prostates with a dual-array (linear and curvilinear) transrectal ultrasound probe. A method to calculate the surface area and, thereby, estimate the laser fluence at this fiber tip was derived, validated, applied to various design parameters, and used as an input to three-dimensional Monte Carlo simulations. Brachytherapy seeds implanted in phantom, ex vivo, and in vivo canine prostates at radial distances of 5 to 30 mm from the urethra were imaged with the fiber prototype transmitting 1064 nm wavelength light with 2 to 8 mJ pulse energy. Prebeamformed images were displayed in real time at a rate of 3 to 5 frames per second to guide fiber placement and beamformed offline. A conventional delay-and-sum beamformer provided decreasing seed contrast (23 to 9 dB) with increasing urethra-to-target distance, while the short-lag spatial coherence beamformer provided improved and relatively constant seed contrast (28 to 32 dB) regardless of distance, thus improving multitarget visualization in single and combined curvilinear images acquired with the fiber rotating and the probe fixed. The proposed light delivery and beamforming methods promise to improve key prostate cancer detection and treatment strategies.

  17. Flexible liquid core light guide with focusing and light shaping attachments

    DOEpatents

    Kross, B.J.; Majewski, S.; Zorn, C.J.; Majewski, L.A.

    1997-11-04

    A liquid light guide system for ultraviolet light is disclosed that has a light shaping arrangement for the emitted light, a stable liquid core and sheath and reliable and effective end closures. 12 figs.

  18. Blood interference in fiber-optical based fluorescence guided resection of glioma using 5-aminolevulinic acid

    NASA Astrophysics Data System (ADS)

    Haj-Hosseini, Neda; Lowndes, Shannely; Salerud, Göran; Wårdell, Karin

    2011-03-01

    Fluorescence guidance in brain tumor resection is performed intra-operatively where bleeding is included. When using fiber-optical probes, the transmission of light to and from the tissue is totally or partially blocked if a small amount of blood appears in front of the probe. Sometimes even after rinsing with saline, the remnant blood cells on the optical probe head, disturb the measurements. In such a case, the corresponding spectrum cannot be reliably quantified and is therefore discarded. The optimal case would be to calculate and take out the blood effect systematically from the collected signals. However, the first step is to study the pattern of blood interference in the fluorescence spectrum. In this study, a fiber-optical based fluorescence spectroscopy system with a laser excitation light of 405 nm (1.4 J/cm2) was used during fluorescence guided brain tumor resection using 5-aminolevulinic acid (5-ALA). The blood interference pattern in the fluorescence spectrum collected from the brain was studied in two patients. The operation situation was modeled in the laboratory by placing blood drops from the finger tip on the skin of forearm and the data was compared to the brain in vivo measurements. Additionally, a theoretical model was developed to simulate the blood interference pattern on the skin autofluorescence. The blood affects the collected fluorescence intensity and leaves traces of oxy and deoxy-hemoglobin absorption peaks. According to the developed theoretical model, the autofluorescence signal is considered to be totally blocked by an approximately 500 μm thick blood layer.

  19. Performance characteristics of an interventional multispectral photoacoustic imaging system for guiding minimally invasive procedures

    PubMed Central

    Mari, Jean Martial; West, Simeon J.; Pratt, Rosalind; David, Anna L.; Ourselin, Sebastien; Beard, Paul C.; Desjardins, Adrien E.

    2016-01-01

    Precise device guidance is important for interventional procedures in many different clinical fields including fetal medicine, regional anesthesia, interventional pain management, and interventional oncology. While ultrasound is widely used in clinical practice for real-time guidance, the image contrast that it provides can be insufficient for visualizing tissue structures such as blood vessels, nerves, and tumors. This study was centered on the development of a photoacoustic imaging system for interventional procedures that delivered excitation light in the ranges of 750 to 900 nm and 1150 to 1300 nm, with an optical fiber positioned in a needle cannula. Coregistered B-mode ultrasound images were obtained. The system, which was based on a commercial ultrasound imaging scanner, has an axial resolution in the vicinity of 100 μm and a submillimeter, depth-dependent lateral resolution. Using a tissue phantom and 800 nm excitation light, a simulated blood vessel could be visualized at a maximum distance of 15 mm from the needle tip. Spectroscopic contrast for hemoglobin and lipids was observed with ex vivo tissue samples, with photoacoustic signal maxima consistent with the respective optical absorption spectra. The potential for further optimization of the system is discussed. PMID:26263417

  20. Multipurpose fiber-optic sensor with sloped tip

    NASA Astrophysics Data System (ADS)

    Melnik, Ivan S.; Krivokhizha, A. M.; Ptashnik, O. V.

    1991-08-01

    Fiber-optic sensors C FOS) are wi. del y used for rioncontact measurements due to their simplicity, small size, insensitivity to I nfl uence of el ectromagneti C fiel ds , hi gh metrol ogi cal characteristics, etc. The operation principle of FOS with intensity modul ati on techni que I s based on the photodetector regi strati on of 1ight , reflected from the control 1 ed surface E I ) . The i ntensi ty of detected 1 1 ght depends on th FOS' s di stance from the control 1 ed surface, its form and inclination to sensor's axis, FOS shift speed, etc. So they can be consider multipurpose. We are devel opi ng FOS wi th i ntensi ty modul ati on techni que wi th traight tips as well as with sloped tips. In FOS with sloped tips the light ring spot is appearing on the controlled surface due to the effect of symmetry. We use thi s phenomena to empl oy refl ected 1 i ght more efficiently and to increase the FOS characteristics. Tak i ng I nto account the fact that pr obl ems of cal cul aWl on of fibers with sloped tip were not analyzed in details earlier-, in particular, only the case of light distribution of parallel beams runni ng was consi dered E 2) we wi I 1 conduct a consi stent cal cul ati on of bounds of i rradi ance fi ci d , created by a fi ber wi th sl oped tip, esti mate I i ght di stri buti on I n a 1 1 ght spot , and determi. ne characteristics of the FOS with sloped tip.

  1. AMERICAN STANDARD GUIDE FOR SCHOOL LIGHTING.

    ERIC Educational Resources Information Center

    Illuminating Engineering Society, New York, NY.

    THIS IS A GUIDE FOR SCHOOL LIGHTING, DESIGNED FOR EDUCATORS AS WELL AS ARCHITECTS. IT MAKES USE OF RECENT RESEARCH, NOTABLY THE BLACKWELL REPORT ON EVALUATION OF VISUAL TASKS. THE GUIDE BEGINS WITH AN OVERVIEW OF CHANGING GOALS AND NEEDS OF SCHOOL LIGHTING, AND A TABULATION OF COMMON CLASSROOM VISUAL TASKS THAT REQUIRE VARIATIONS IN LIGHTING.…

  2. Image fusion-guided portal vein puncture during transjugular intrahepatic portosystemic shunt placement.

    PubMed

    Rouabah, K; Varoquaux, A; Caporossi, J M; Louis, G; Jacquier, A; Bartoli, J M; Moulin, G; Vidal, V

    2016-11-01

    The purpose of this study was to assess the feasibility and utility of image fusion (Easy-TIPS) obtained from pre-procedure CT angiography and per-procedure real-time fluoroscopy for portal vein puncture during transjugular intrahepatic portosystemic shunt (TIPS) placement. Eighteen patients (15 men, 3 women) with a mean age of 63 years (range: 48-81 years; median age, 65 years) were included in the study. All patients underwent TIPS placement by two groups of radiologists (one group with radiologists of an experience<3 years and one with an experience≥3 years) using fusion imaging obtained from three-dimensional computed tomography angiography of the portal vein and real-time fluoroscopic images of the portal vein. Image fusion was used to guide the portal vein puncture during TIPS placement. At the end of the procedure, the interventional radiologists evaluated the utility of fusion imaging for portal vein puncture during TIPS placement. Mismatch between three-dimensional computed tomography angiography and real-time fluoroscopic images of the portal vein on image fusion was quantitatively analyzed. Posttreatment CT time, number of the puncture attempts, total radiation exposure and radiation from the retrograde portography were also recorded. Image fusion was considered useful for portal vein puncture in 13/18 TIPS procedures (72%). The mean posttreatment time to obtain fusion images was 16.4minutes. 3D volume rendered CT angiography images was strictly superimposed on direct portography in 10/18 procedures (56%). The mismatch mean value was 0.69cm in height and 0.28cm laterally. A mean number of 4.6 portal vein puncture attempts was made. Eight patients required less than three attempts. The mean radiation dose from retrograde portography was 421.2dGy.cm 2 , corresponding to a mean additional exposure of 19%. Fusion imaging resulting from image fusion from pre-procedural CT angiography is feasible, safe and makes portal puncture easier during TIPS placement. Copyright © 2016 Editions françaises de radiologie. Published by Elsevier Masson SAS. All rights reserved.

  3. 7. VIEW OF TIP TOP AND PHILLIPS MINES. PHOTO MADE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. VIEW OF TIP TOP AND PHILLIPS MINES. PHOTO MADE FROM THE 'NOTTINGHAM' SADDLE VISIBLE IN PHOTOGRAPHS ID-31-3 AND ID-31-6. CAMERA POINTED NORTHEAST TIP TOP IS CLEARLY VISIBLE IN UPPER RIGHT; RUNNING A STRAIGHT EDGE THROUGH THE TRUNK LINE OF SMALL TREE IN LOWER RIGHT THROUGH TRUNK LINE OF LARGER TREE WILL DIRECT ONE TO LIGHT AREA WHERE TIP TOP IS LOCATED; BLACK SQUARE IS THE RIGHT WINDOW ON WEST SIDE (FRONT) OF STRUCTURE. PHILLIPS IS VISIBLE BY FOLLOWING TREE LINE DIAGONALLY THROUGH IMAGE TO FAR LEFT SIDE. SULLIVAN IS HIDDEN IN THE TREE TO THE RIGHT OF PHILLIPS. - Florida Mountain Mining Sites, Silver City, Owyhee County, ID

  4. Light Rail Transit Car Specification Guide

    DOT National Transportation Integrated Search

    1981-12-01

    This Light Rail Transit Car Specification Guide is not a procurement document in itself. It is intended to be used as a guide by light rail transit operators and purchasers of such equipment in the preparation of technical specifications. Because of ...

  5. Characterizing nanoscale scanning probes using electron microscopy: A novel fixture and a practical guide

    NASA Astrophysics Data System (ADS)

    Jacobs, Tevis D. B.; Wabiszewski, Graham E.; Goodman, Alexander J.; Carpick, Robert W.

    2016-01-01

    The nanoscale geometry of probe tips used for atomic force microscopy (AFM) measurements determines the lateral resolution, contributes to the strength of the tip-surface interaction, and can be a significant source of uncertainty in the quantitative analysis of results. While inverse imaging of the probe tip has been used successfully to determine probe tip geometry, direct observation of the tip profile using electron microscopy (EM) confers several advantages: it provides direct (rather than indirect) imaging, requires fewer algorithmic parameters, and does not require bringing the tip into contact with a sample. In the past, EM-based observation of the probe tip has been achieved using ad hoc mounting methods that are constrained by low throughput, the risk of contamination, and repeatability issues. We report on a probe fixture designed for use in a commercial transmission electron microscope that enables repeatable mounting of multiple AFM probes as well as a reference grid for beam alignment. This communication describes the design, fabrication, and advantages of this probe fixture, including full technical drawings for machining. Further, best practices are discussed for repeatable, non-destructive probe imaging. Finally, examples of the fixture's use are described, including characterization of common commercial AFM probes in their out-of-the-box condition.

  6. Probing Redox Reactions at the Nanoscale with Electrochemical Tip-Enhanced Raman Spectroscopy

    DTIC Science & Technology

    2015-11-18

    The scattered light was collected through the Nikon objective, passed through a long-pass filter (LP03-633RS-25, Semrock ) to filter Rayleigh light and...25, Semrock ). The light was then focused into a 1/3 m spectrograph (SP2300, Princeton Instruments), dispersed (1200 grooves/nm, 500 nm blaze), and

  7. Better to light a candle than curse the darkness: illuminating spatial localization and temporal dynamics of rapid microbial growth in the rhizosphere

    PubMed Central

    Herron, Patrick M.; Gage, Daniel J.; Arango Pinedo, Catalina; Haider, Zane K.; Cardon, Zoe G.

    2013-01-01

    The rhizosphere is a hotbed of microbial activity in ecosystems, fueled by carbon compounds from plant roots. Basic questions about the location and dynamics of plant-spurred microbial growth in the rhizosphere are difficult to answer with standard, destructive soil assays mixing a multitude of microbe-scale microenvironments in a single, often sieved, sample. Soil microbial biosensors designed with the luxCDABE reporter genes fused to a promoter of interest enable continuous imaging of the microbial perception of (and response to) environmental conditions in soil. We used the common soil bacterium Pseudomonas putida KT2440 as host to plasmid pZKH2 containing a fusion between the strong constitutive promoter nptII and luxCDABE (coding for light-emitting proteins) from Vibrio fischeri. Experiments in liquid media demonstrated that high light production by KT2440/pZKH2 was associated with rapid microbial growth supported by high carbon availability. We applied the biosensors in microcosms filled with non-sterile soil in which corn (Zea mays L.), black poplar (Populus nigra L.), or tomato (Solanum lycopersicum L.) was growing. We detected minimal light production from microbiosensors in the bulk soil, but biosensors reported continuously from around roots for as long as six days. For corn, peaks of luminescence were detected 1–4 and 20–35 mm along the root axis behind growing root tips, with the location of maximum light production moving farther back from the tip as root growth rate increased. For poplar, luminescence around mature roots increased and decreased on a coordinated diel rhythm, but was not bright near root tips. For tomato, luminescence was dynamic, but did not exhibit a diel rhythm, appearing in acropetal waves along roots. KT2440/pZKH2 revealed that root tips are not always the only, or even the dominant, hotspots for rhizosphere microbial growth, and carbon availability is highly variable in space and time around roots. PMID:24032034

  8. Primer for Using RE-Powering Data to Screen Sites for Renewable Energy Potential

    EPA Pesticide Factsheets

    This reference guide provides users with tips for using the RE-Powering Screening Dataset spreadsheet, which contains detailed site information on over 60,000 contaminated lands, landfills, and mine sites.

  9. Histograms and Frequency Density.

    ERIC Educational Resources Information Center

    Micromath, 2003

    2003-01-01

    Introduces exercises on histograms and frequency density. Guides pupils to Discovering Important Statistical Concepts Using Spreadsheets (DISCUSS), created at the University of Coventry. Includes curriculum points, teaching tips, activities, and internet address (http://www.coventry.ac.uk/discuss/). (KHR)

  10. Breaking into Print: A Beginner's Guide to Self-Publishing.

    ERIC Educational Resources Information Center

    Coelho, Elizabeth

    1988-01-01

    Outlines the business and production aspects of self-publishing, with some tips for desktop publishing, as it involves the design and development of Canadian English-as a-second-language instructional materials. (Author/CB)

  11. The Polychromatic Laser Guide Star: the ELP-OA demonstrator at Observatoire de Haute Provence

    NASA Astrophysics Data System (ADS)

    Foy, R.; Chatagnat, M.; Dubet, D.; Éric, P.; Eysseric, J.; Foy, F.-C.; Fusco, T.; Girard, J.; Laloge, A.; Le van Suu, A.; Messaoudi, B.; Perruchot, S.; Richaud, P.; Richaud, Y.; Rondeau, X.; Tallon, M.; Thiébaut, É.; Boër, M.

    2007-07-01

    The correction of the tilt for adaptive optics devices from the only laser guide star can be done with the polychromatic laser guide star. We report the progress of the first demonstrator of the implementation of this concept, at Observatoire de Haute-Provence. We review the last steps of the feasibility studies, the optimization of the laser parameters, and the studies of the implementation at the OHP 1.52m telescope, including the beam propagation to the lasers room to the mesosphere and the algorithms for tip-tilt measurements.

  12. C-arm cone beam computed tomography needle path overlay for fluoroscopic guided vertebroplasty.

    PubMed

    Tam, Alda L; Mohamed, Ashraf; Pfister, Marcus; Chinndurai, Ponraj; Rohm, Esther; Hall, Andrew F; Wallace, Michael J

    2010-05-01

    Retrospective review. To report our early clinical experience using C-arm cone beam computed tomography (C-arm CBCT) with fluoroscopic overlay for needle guidance during vertebroplasty. C-arm CBCT is advanced three-dimensional (3-D) imaging technology that is currently available on state-of-the-art flat panel based angiography systems. The imaging information provided by C-arm CBCT allows for the acquisition and reconstruction of "CT-like" images in flat panel based angiography/interventional suites. As part of the evolution of this technology, enhancements allowing the overlay of cross-sectional imaging information can now be integrated with real time fluoroscopy. We report our early clinical experience with C-arm CBCT with fluoroscopic overlay for needle guidance during vertebroplasty. This is a retrospective review of 10 consecutive oncology patients who underwent vertebroplasty of 13 vertebral levels using C-arm CBCT with fluoroscopic overlay for needle guidance from November 2007 to December 2008. Procedural data including vertebral level, approach (transpedicular vs. extrapedicular), access (bilateral vs. unilateral) and complications were recorded. Technical success with the overlay technology was assessed based on accuracy which consisted of 4 measured parameters: distance from target to needle tip, distance from planned path to needle tip, distance from midline to needle tip, and distance from the anterior 1/3 of the vertebral body to needle tip. Success within each parameter required that the distance between the needle tip and parameter being evaluated be no more than 5 mm on multiplanar CBCT or fluoroscopy. Imaging data for 12 vertebral levels was available for review. All vertebral levels were treated using unilateral access and 9 levels were treated with an extrapedicular approach. Technical success rates were 92% for both distance from planned path and distance from midline to final needle tip, 100% when distance from needle tip to the anterior 1/3 border of the vertebral body was measured, and 75% when distance from target to needle tip was measured. There were no major complications. Minor complications consisted of 3 cases (25%) of cement extravasation. C-arm CBCT with needle path overlay for fluoroscopic guided vertebroplasty is feasible and allows for reliable unilateral therapy of both lumbar and thoracic vertebral bodies. Extrapedicular approaches were performed safely and with good accuracy of reaching the targets.

  13. Multi-layered fabrication of large area PDMS flexible optical light guide sheets

    NASA Astrophysics Data System (ADS)

    Green, Robert; Knopf, George K.; Bordatchev, Evgueni V.

    2017-02-01

    Large area polydimethylsiloxane (PDMS) flexible optical light guide sheets can be used to create a variety of passive light harvesting and illumination systems for wearable technology, advanced indoor lighting, non-planar solar light collectors, customized signature lighting, and enhanced safety illumination for motorized vehicles. These thin optically transparent micro-patterned polymer sheets can be draped over a flat or arbitrarily curved surface. The light guiding behavior of the optical light guides depends on the geometry and spatial distribution of micro-optical structures, thickness and shape of the flexible sheet, refractive indices of the constituent layers, and the wavelength of the incident light. A scalable fabrication method that combines soft-lithography, closed thin cavity molding, partial curing, and centrifugal casting is described in this paper for building thin large area multi-layered PDMS optical light guide sheets. The proposed fabrication methodology enables the of internal micro-optical structures (MOSs) in the monolithic PDMS light guide by building the optical system layer-by-layer. Each PDMS layer in the optical light guide can have the similar, or a slightly different, indices of refraction that permit total internal reflection within the optical sheet. The individual molded layers may also be defect free or micro-patterned with microlens or reflecting micro-features. In addition, the bond between adjacent layers is ensured because each layer is only partially cured before the next functional layer is added. To illustrate the scalable build-by-layers fabrication method a three-layer mechanically flexible illuminator with an embedded LED strip is constructed and demonstrated.

  14. Renal sympathetic denervation using an externally irrigated radiofrequency ablation catheter for treatment of resistant hypertension - Acute safety and short term efficacy.

    PubMed

    Yalagudri, Sachin; Raju, Narayana; Das, Bharati; Daware, Ashwin; Maiya, Shreesha; Jothiraj, Kannan; Ravikishore, A G

    2015-01-01

    This study was conducted to assess the acute safety and short term efficacy of renal sympathetic denervation (RSDN) using solid tip radiofrequency ablation (RFA) catheter and saline irrigation through the renal guiding catheter to achieve effective denervation. RSDN using a specialized solid-tip RFA catheter has recently been demonstrated to safely reduce systemic blood pressure in patients with refractory hypertension, the limitation being inadequate power delivery in renal arteries. So, we used solid-tip RFA catheter along with saline irrigation for RSDN. Nine patients with resistant hypertension underwent CT and conventional renal angiography, followed by bilateral or unilateral RSDN using 5F RFA catheter with saline irrigation through renal guiding catheter. Repeat renal angiography was performed at the end of the procedure. In all patients, pre- and post-procedure serum creatinine was measured. Over 1-month period: 1) the systolic/diastolic blood pressure decreased by -57 ± 20/-25 ± 7.5 mm Hg; 2) all patients experienced a decrease in systolic blood pressure of at least -36 mm Hg (range 36-98 mm Hg); 3) there was no evidence of renal artery injury immediate post-procedure. There was no significant change in serum creatinine level. This data shows the acute procedural safety and short term efficacy of RSDN using modified externally irrigated solid tip RFA catheter. Copyright © 2015 Cardiological Society of India. Published by Elsevier B.V. All rights reserved.

  15. Needle position estimation from sub-sampled k-space data for MRI-guided interventions

    NASA Astrophysics Data System (ADS)

    Schmitt, Sebastian; Choli, Morwan; Overhoff, Heinrich M.

    2015-03-01

    MRI-guided interventions have gained much interest. They profit from intervention synchronous data acquisition and image visualization. Due to long data acquisition durations, ergonomic limitations may occur. For a trueFISP MRI-data acquisition sequence, a time sparing sub-sampling strategy has been developed that is adapted to amagnetic needle detection. A symmetrical and contrast rich susceptibility needle artifact, i.e. an approximately rectangular gray scale profile is assumed. The 1-D-Fourier transformed of a rectangular function is a sinc-function. Its periodicity is exploited by sampling only along a few orthogonal trajectories in k-space. Because a needle moves during intervention, its tip region resembles a rectangle in a time-difference image that is reconstructed from such sub-sampled k-spaces acquired at different time stamps. In different phantom experiments, a needle was pushed forward along a reference trajectory, which was determined from a needle holders geometric parameters. In addition, the trajectory of the needle tip was estimated by the method described above. Only ca. 4 to 5% of the entire k-space data was used for needle tip estimation. The misalignment of needle orientation and needle tip position, i.e. the differences between reference and estimated values, is small and even in its worst case less than 2 mm. The results show that the method is applicable under nearly real conditions. Next steps are addressed to the validation of the method for clinical data.

  16. Silicon technology-based micro-systems for atomic force microscopy/photon scanning tunnelling microscopy.

    PubMed

    Gall-Borrut, P; Belier, B; Falgayrettes, P; Castagne, M; Bergaud, C; Temple-Boyer, P

    2001-04-01

    We developed silicon nitride cantilevers integrating a probe tip and a wave guide that is prolonged on the silicon holder with one or two guides. A micro-system is bonded to a photodetector. The resulting hybrid system enables us to obtain simultaneously topographic and optical near-field images. Examples of images obtained on a longitudinal cross-section of an optical fibre are shown.

  17. Back-to-School Guide: Jump-Start Learning with New Media. Updated with New Tools and Resources for 2010-11

    ERIC Educational Resources Information Center

    George Lucas Educational Foundation, 2010

    2010-01-01

    To help teachers get off to a good start, this paper presents the updated "Back-to-School Guide" that is brimming with new-media ideas and resources. It outlines ten tips, along with easy-to-use tools, that will help teachers build their classroom community, survey students to bring out their ideas, and make learning more collaborative. Links to…

  18. A deflectable guiding catheter for real-time MRI-guided interventions

    PubMed Central

    Bell, Jamie A.; Saikus, Christina E.; Ratnakaya, Kanishka; Wu, Vincent; Sonmez, Merdim; Faranesh, Anthony Z.; Colyer, Jessica H.; Lederman, Robert J.; Kocaturk, Ozgur

    2011-01-01

    Purpose To design a deflectable guiding catheter that omits long metallic components yet preserves mechanical properties to facilitate therapeutic interventional MRI procedures. Materials and Methods The catheter shaft incorporated Kevlar braiding. 180° deflection was attained with a 5 cm nitinol slotted tube, a nitinol spring, and a Kevlar pull string. We tested three designs: passive, passive incorporating an inductively-coupled coil, and active receiver. We characterized mechanical properties, MRI properties, RF induced heating, and in vivo performance in swine. Results Torque and tip deflection force were satisfactory. Representative procedures included hepatic and azygos vein access, laser cardiac septostomy, and atrial septal defect crossing. Visualization was best in the active configuration, delineating profile and tip orientation. The passive configuration could be used in tandem with an active guidewire to overcome its limited conspicuity. There was no RF-induced heating in all configurations under expected use conditions in vitro and in vivo. Conclusion Kevlar and short nitinol component substitutions preserved mechanical properties. The active design offered the best visibility and usability but reintroduced metal conductors. We describe versatile deflectable guiding catheters with a 0.057” lumen for interventional MRI catheterization. Implementations are feasible using active, inductive, and passive visualization strategies to suit application requirements. PMID:22128071

  19. Design and fabrication of sub-wavelength annular apertures on fiber tip for femtosecond laser machining

    NASA Astrophysics Data System (ADS)

    Tung, Yen-Chun; Chung, Ming-Han; Sung, I.-Hui; Lee, Chih-Kung

    2014-03-01

    Adopting optical technique to pursue micromachining must make a compromise between the focal spot sizes the depth of focus. The focal spot size determines the minimum features can be fabricated. On the other hand, the depth of focus influences the ease of alignment in positioning the fabrication light beam. A typical approach to bypass the diffraction limit is to adopt the near-field approach, which has spot size in the range of the optical fiber tip. However, the depth of focus of the emitted light beam will be limited to tens of nanometers in most cases, which posts a difficult challenge to control the distance between the optical fiber tip and the sample to be machined optically. More specifically, problems remained in this machining approach, which include issues such as residue induced by laser ablation tends to deposit near the optical fiber tip and leads to loss of coupling efficiency. We proposed a method based on illuminating femtosecond laser through a sub-wavelength annular aperture on metallic film so as to produce Bessel light beam of sub-wavelength while maintaining large depth of focus first. To further advance the ease of use in one such system, producing sub-wavelength annular aperture on a single mode optical fiber head with sub-wavelength focusing ability is detailed. It is shown that this method can be applied in material machining with an emphasis to produce high aspect ratio structure. Simulations and experimental results are presented in this paper.

  20. Dark conditions enhance aluminum tolerance in several rice cultivars via multiple modulations of membrane sterols.

    PubMed

    Wagatsuma, Tadao; Maejima, Eriko; Watanabe, Toshihiro; Toyomasu, Tomonobu; Kuroda, Masaharu; Muranaka, Toshiya; Ohyama, Kiyoshi; Ishikawa, Akifumi; Usui, Masami; Hossain Khan, Shahadat; Maruyama, Hayato; Tawaraya, Keitaro; Kobayashi, Yuriko; Koyama, Hiroyuki

    2018-01-23

    Aluminum-sensitive rice (Oryza sativa L.) cultivars showed increased Al tolerance under dark conditions, because less Al accumulated in the root tips (1 cm) under dark than under light conditions. Under dark conditions, the root tip concentration of total sterols, which generally reduce plasma membrane permeabilization, was higher in the most Al-sensitive japonica cultivar, Koshihikari (Ko), than in the most Al-tolerant cultivar, Rikuu-132 (R132), but the phospholipid content did not differ between the two. The Al treatment increased the proportion of stigmasterol (which has no ability to reduce membrane permeabilization) out of total sterols similarly in both cultivars under light conditions, but it decreased more in Ko under dark conditions. The carotenoid content in the root tip of Al-treated Ko was significantly lower under dark than under light conditions, indicating that isopentenyl diphosphate transport from the cytosol to plastids was decreased under dark conditions. HMG2 and HMG3 (encoding the key sterol biosynthetic enzyme 3-hydroxy-3-methylglutaryl CoA reductase) transcript levels in the root tips were enhanced under dark conditions. We suggest that the following mechanisms contribute to the increase in Al tolerance under dark conditions: inhibition of stigmasterol formation to retain membrane integrity; greater partitioning of isopentenyl diphosphate for sterol biosynthesis; and enhanced expression of HMGs to increase sterol biosynthesis. © The Author(s) 2017. Published by Oxford University Press on behalf of the Society for Experimental Biology.

  1. Optical fiber tip with point light source of SPPs driven by three-dimensional nanostructured asymmetric metal-insulator-metal layer cap

    NASA Astrophysics Data System (ADS)

    Oshikane, Yasushi; Murai, Kensuke; Nakano, Motohiro

    2015-09-01

    Numerical analysis of three dimensional optical electro-magnetic field in a circular-truncated conical optical fiber covered by asymmetric MIM structure has been performed by a commercial finite element method package, COMSOL Multiphysics coupled with Wave Optics Module. The outermost thick metallic layer has twin nano-hole, and the waveguiding twin-hole could draw surface plasmon polaritions (SPPs) excited in the MIM structure to the surface. Finally the guided two SPPs could unite each other and may create a single bright spot. The systematic simulation is continuing, and the results will give us valuable counsel for control of surface plasmon polaritons (SPPs) appearing around the MIM structure and twin nano-hole. (1) Optimal design of the 3D FEM model for 8-core Xeon server and rational approach for the FEM analysis, (2) behavior of SPPs affected by wavelength and polarization of light travel through fiber, (3) change in excitation condition of SPPs caused by shape of the MIM structure and twin-hole, (4) effectiveness of additional nanostructures that are aimed at focusing control of two SPPs come out from the corners of twin-hole, (5) scanning ability of the MIM/twin-hole probe at nanostructured sample surface (i.e. amount of forward and backward scattering of SPPs) will be presented and discussed. Several FIBed prototypes and their characteristic of light emission will also reported.

  2. Evolution of quality characteristics of minimally processed asparagus during storage in different lighting conditions.

    PubMed

    Sanz, S; Olarte, C; Ayala, F; Echávarri, J F

    2009-08-01

    The effect of different types of lighting (white, green, red, and blue light) on minimally processed asparagus during storage at 4 degrees C was studied. The gas concentrations in the packages, pH, mesophilic counts, and weight loss were also determined. Lighting caused an increase in physiological activity. Asparagus stored under lighting achieved atmospheres with higher CO(2) and lower O(2) content than samples kept in the dark. This activity increase explains the greater deterioration experienced by samples stored under lighting, which clearly affected texture and especially color, accelerating the appearance of greenish hues in the tips and reddish-brown hues in the spears. Exposure to light had a negative effect on the quality parameters of the asparagus and it caused a significant reduction in shelf life. Hence, the 11 d shelf life of samples kept in the dark was reduced to only 3 d in samples kept under red and green light, and to 7 d in those kept under white and blue light. However, quality indicators such as the color of the tips and texture showed significantly better behavior under blue light than with white light, which allows us to state that it is better to use this type of light or blue-tinted packaging film for the display of minimally processed asparagus to consumers.

  3. Red light-induced suppression of gravitropism in moss protonemata

    NASA Astrophysics Data System (ADS)

    Kern, V. D.; Sack, F. D.

    1999-01-01

    Moss protonemata are among the few cell types known that both sense and respond to gravity and light. Apical cells of Ceratodon protonemata grow by oriented tip growth which is negatively gravitropic in the dark or positively phototropic in unilateral red light. Phototropism is phytochrome-mediated. To determine whether any gravitropism persists during irradiation, cultures were turned at various angles with respect to gravity and illuminated so that the light and gravity vectors acted either in the same or in different directions. Red light for 24h (≥140nmol m-2s-1) caused the protonemata to be oriented directly towards the light. Similarly, protonemata grew directly towards the light regardless of light position with respect to gravity indicating that all growth is oriented strictly by phototropism, not gravitropism. At light intensities ≤100nmol m-2s-1, no phototropism occurs and the mean protonemal tip angle remains above the horizontal, which is the criterion for negative gravitropism. But those protonemata are not as uniformly upright as they would be in the dark indicating that low intensity red light permits gravitropism but also modulates the response. Protonemata of the aphototropic mutant ptr1 that lacks a functional Pfr chromophore, exhibit gravitropism regardless of red light intensity. This indicates that red light acts via Pfr to modulate gravitropism at low intensities and to suppress gravitropism at intensities ≥140nmol m-2s-1.

  4. Frequency-dependent photothermal measurement of transverse thermal diffusivity of organic semiconductors

    NASA Astrophysics Data System (ADS)

    Brill, J. W.; Shahi, Maryam; Payne, Marcia M.; Edberg, Jesper; Yao, Y.; Crispin, Xavier; Anthony, J. E.

    2015-12-01

    We have used a photothermal technique, in which chopped light heats the front surface of a small (˜1 mm2) sample and the chopping frequency dependence of thermal radiation from the back surface is measured with a liquid-nitrogen-cooled infrared detector. In our system, the sample is placed directly in front of the detector within its dewar. Because the detector is also sensitive to some of the incident light, which leaks around or through the sample, measurements are made for the detector signal that is in quadrature with the chopped light. Results are presented for layered crystals of semiconducting 6,13-bis(triisopropylsilylethynyl) pentacene (TIPS-pn) and for papers of cellulose nanofibrils coated with semiconducting poly(3,4-ethylene-dioxythiophene):poly(styrene-sulfonate) (NFC-PEDOT). For NFC-PEDOT, we have found that the transverse diffusivity, smaller than the in-plane value, varies inversely with thickness, suggesting that texturing of the papers varies with thickness. For TIPS-pn, we have found that the interlayer diffusivity is an order of magnitude larger than the in-plane value, consistent with previous estimates, suggesting that low-frequency optical phonons, presumably associated with librations in the TIPS side groups, carry most of the heat.

  5. Chip-on-the-tip compact flexible endoscopic epifluorescence video-microscope for in-vivo imaging in medicine and biomedical research

    PubMed Central

    Matz, Gregor; Messerschmidt, Bernhard; Göbel, Werner; Filser, Severin; Betz, Christian S.; Kirsch, Matthias; Uckermann, Ortrud; Kunze, Marcel; Flämig, Sven; Ehrhardt, André; Irion, Klaus-Martin; Haack, Mareike; Dorostkar, Mario M.; Herms, Jochen; Gross, Herbert

    2017-01-01

    We demonstrate a 60 mg light video-endomicroscope with a cylindrical shape of the rigid tip of only 1.6 mm diameter and 6.7 mm length. A novel implementation method of the illumination unit in the endomicroscope is presented. It allows for the illumination of the biological sample with fiber-coupled LED light at 455 nm and the imaging of the red-shifted fluorescence light above 500 nm in epi-direction. A large numerical aperture of 0.7 leads to a sub-cellular resolution and yields to high-contrast images within a field of view of 160 μm. A miniaturized chip-on-the-tip CMOS image sensor with more than 150,000 pixels captures the multicolor images at 30 fps. Considering size, plug-and-play capability, optical performance, flexibility and weight, we hence present a probe which sets a new benchmark in the field of epifluorescence endomicroscopes. Several ex-vivo and in-vivo experiments in rodents and humans suggest future application in biomedical fields, especially in the neuroscience community, as well as in medical applications targeting optical biopsies or the detection of cellular anomalies. PMID:28717570

  6. Conformal Regge theory

    NASA Astrophysics Data System (ADS)

    Goncalves, Vasco David Fonseca

    The work described in this PhD Thesis focuses on the post-processing of optical fibers and their enhancement as sensing element. Since the majority of sensors presented are based in Fabry-Perot interferometers, an historical overview of this category of optical fiber sensors is firstly presented. This review considers the works published since the early years, in the beginning of the 1980s, until the middle of 2015. The incorporation of microcavities at the tip of a single mode fiber was extensively studied, particularly for the measurement of nitrogen and methane gas pressure. These cavities were fabricated using hollow core silica tubes and a hollow core photonic crystal fiber. Following a different approach, the microcavities were incorporated between two sections of single mode fiber. In this case, the low sensitivity to temperature makes these microcavities highly desirable for the measurement of strain at high temperatures. Competences in post-processing techniques such as the chemical etching and the writing of periodical structures in the fiber core by means of an excimer or a femtosecond laser were also acquired in the course of the PhD programme. One of the works consisted in the design and manufacturing of a double clad optical fiber. The refractive index of the inner cladding was higher than the one of the outer cladding and the core. Thus, light was guided in the inner cladding instead of propagating in the core. This situation was overcome by applying chemical etching, thus removing the inner cladding. The core, surrounded by air, was then able to guide light. Two different applications were found for this fiber, as a temperature sensor and as an optical refractometer. In the last, the optical phase changes with the liquid refractive index. Two different types of fiber Bragg gratings were characterized in strain and temperature. Sensing structures obtained through the phase mask technique at the tip of an optical fiber were subjected to chemical etching. In this case, an excimer laser was used. Extremely thin fiber tips were obtained, with an ultra-high sensitivity to strain. The other technique employed to fabricate the fiber Bragg gratings was the point-by-point femtosecond laser inscription. In this case, the sensing elements are very stable at high temperatures and can be used to measure strain in harsh conditions. The employment of optical fiber lasers as sensing elements was also considered in this Thesis. Two laser cavities were studied, one based on the ring configuration and the other based on a figure-of-eight configuration. From these works, the quality of the laser emission, namely the signal-to-noise ratio, the reduced full-width at half maximum and the stability should be highlighted. These characteristics allowed the measurement of different physical parameters, such as strain, temperature and torsion. Lastly, the possibility to use microspheres as sensing elements was considered. Using the electric arc of a fusion splicer, it is possible to create microspheres at the tip of an optical fiber. Furthermore, with this technique it is chains of microspheres can be obtained, constituting Mach-Zehnder-type interferometers which are sensitive to physical parameters like strain and temperature. The preliminary results obtained by introducing silica microspheres in a support structure are also presented. In this case, the sensors were subjected to temperature variations. All the experimental work was combined with the respective theoretical considerations. Many questions have been raised with the course of this PhD, and there are still some without a definite answer. Thus, new research paths can be followed, having their basis grounded in the configurations here presented.

  7. Analytical Applications of Fluorescent Carbon Dots

    NASA Astrophysics Data System (ADS)

    Goncalves, Helena Maria Rodrigues

    The work described in this PhD Thesis focuses on the post-processing of optical fibers and their enhancement as sensing element. Since the majority of sensors presented are based in Fabry-Perot interferometers, an historical overview of this category of optical fiber sensors is firstly presented. This review considers the works published since the early years, in the beginning of the 1980s, until the middle of 2015. The incorporation of microcavities at the tip of a single mode fiber was extensively studied, particularly for the measurement of nitrogen and methane gas pressure. These cavities were fabricated using hollow core silica tubes and a hollow core photonic crystal fiber. Following a different approach, the microcavities were incorporated between two sections of single mode fiber. In this case, the low sensitivity to temperature makes these microcavities highly desirable for the measurement of strain at high temperatures. Competences in post-processing techniques such as the chemical etching and the writing of periodical structures in the fiber core by means of an excimer or a femtosecond laser were also acquired in the course of the PhD programme. One of the works consisted in the design and manufacturing of a double clad optical fiber. The refractive index of the inner cladding was higher than the one of the outer cladding and the core. Thus, light was guided in the inner cladding instead of propagating in the core. This situation was overcome by applying chemical etching, thus removing the inner cladding. The core, surrounded by air, was then able to guide light. Two different applications were found for this fiber, as a temperature sensor and as an optical refractometer. In the last, the optical phase changes with the liquid refractive index. Two different types of fiber Bragg gratings were characterized in strain and temperature. Sensing structures obtained through the phase mask technique at the tip of an optical fiber were subjected to chemical etching. In this case, an excimer laser was used. Extremely thin fiber tips were obtained, with an ultra-high sensitivity to strain. The other technique employed to fabricate the fiber Bragg gratings was the point-by-point femtosecond laser inscription. In this case, the sensing elements are very stable at high temperatures and can be used to measure strain in harsh conditions. The employment of optical fiber lasers as sensing elements was also considered in this Thesis. Two laser cavities were studied, one based on the ring configuration and the other based on a figure-of-eight configuration. From these works, the quality of the laser emission, namely the signal-to-noise ratio, the reduced full-width at half maximum and the stability should be highlighted. These characteristics allowed the measurement of different physical parameters, such as strain, temperature and torsion. Lastly, the possibility to use microspheres as sensing elements was considered. Using the electric arc of a fusion splicer, it is possible to create microspheres at the tip of an optical fiber. Furthermore, with this technique it is chains of microspheres can be obtained, constituting Mach-Zehnder-type interferometers which are sensitive to physical parameters like strain and temperature. The preliminary results obtained by introducing silica microspheres in a support structure are also presented. In this case, the sensors were subjected to temperature variations. All the experimental work was combined with the respective theoretical considerations. Many questions have been raised with the course of this PhD, and there are still some without a definite answer. Thus, new research paths can be followed, having their basis grounded in the configurations here presented.

  8. Nanostructured Photoanodes for Solar Cells

    NASA Astrophysics Data System (ADS)

    Apolinario, Arlete Ondina Alves da Silva

    The work described in this PhD Thesis focuses on the post-processing of optical fibers and their enhancement as sensing element. Since the majority of sensors presented are based in Fabry-Perot interferometers, an historical overview of this category of optical fiber sensors is firstly presented. This review considers the works published since the early years, in the beginning of the 1980s, until the middle of 2015. The incorporation of microcavities at the tip of a single mode fiber was extensively studied, particularly for the measurement of nitrogen and methane gas pressure. These cavities were fabricated using hollow core silica tubes and a hollow core photonic crystal fiber. Following a different approach, the microcavities were incorporated between two sections of single mode fiber. In this case, the low sensitivity to temperature makes these microcavities highly desirable for the measurement of strain at high temperatures. Competences in post-processing techniques such as the chemical etching and the writing of periodical structures in the fiber core by means of an excimer or a femtosecond laser were also acquired in the course of the PhD programme. One of the works consisted in the design and manufacturing of a double clad optical fiber. The refractive index of the inner cladding was higher than the one of the outer cladding and the core. Thus, light was guided in the inner cladding instead of propagating in the core. This situation was overcome by applying chemical etching, thus removing the inner cladding. The core, surrounded by air, was then able to guide light. Two different applications were found for this fiber, as a temperature sensor and as an optical refractometer. In the last, the optical phase changes with the liquid refractive index. Two different types of fiber Bragg gratings were characterized in strain and temperature. Sensing structures obtained through the phase mask technique at the tip of an optical fiber were subjected to chemical etching. In this case, an excimer laser was used. Extremely thin fiber tips were obtained, with an ultra-high sensitivity to strain. The other technique employed to fabricate the fiber Bragg gratings was the point-by-point femtosecond laser inscription. In this case, the sensing elements are very stable at high temperatures and can be used to measure strain in harsh conditions. The employment of optical fiber lasers as sensing elements was also considered in this Thesis. Two laser cavities were studied, one based on the ring configuration and the other based on a figure-of-eight configuration. From these works, the quality of the laser emission, namely the signal-to-noise ratio, the reduced full-width at half maximum and the stability should be highlighted. These characteristics allowed the measurement of different physical parameters, such as strain, temperature and torsion. Lastly, the possibility to use microspheres as sensing elements was considered. Using the electric arc of a fusion splicer, it is possible to create microspheres at the tip of an optical fiber. Furthermore, with this technique it is chains of microspheres can be obtained, constituting Mach-Zehnder-type interferometers which are sensitive to physical parameters like strain and temperature. The preliminary results obtained by introducing silica microspheres in a support structure are also presented. In this case, the sensors were subjected to temperature variations. All the experimental work was combined with the respective theoretical considerations. Many questions have been raised with the course of this PhD, and there are still some without a definite answer. Thus, new research paths can be followed, having their basis grounded in the configurations here presented.

  9. Chemoselectivity of Immobilized Transition Metal Catalysts

    NASA Astrophysics Data System (ADS)

    Teixeira, Filipe

    The work described in this PhD Thesis focuses on the post-processing of optical fibers and their enhancement as sensing element. Since the majority of sensors presented are based in Fabry-Perot interferometers, an historical overview of this category of optical fiber sensors is firstly presented. This review considers the works published since the early years, in the beginning of the 1980s, until the middle of 2015. The incorporation of microcavities at the tip of a single mode fiber was extensively studied, particularly for the measurement of nitrogen and methane gas pressure. These cavities were fabricated using hollow core silica tubes and a hollow core photonic crystal fiber. Following a different approach, the microcavities were incorporated between two sections of single mode fiber. In this case, the low sensitivity to temperature makes these microcavities highly desirable for the measurement of strain at high temperatures. Competences in post-processing techniques such as the chemical etching and the writing of periodical structures in the fiber core by means of an excimer or a femtosecond laser were also acquired in the course of the PhD programme. One of the works consisted in the design and manufacturing of a double clad optical fiber. The refractive index of the inner cladding was higher than the one of the outer cladding and the core. Thus, light was guided in the inner cladding instead of propagating in the core. This situation was overcome by applying chemical etching, thus removing the inner cladding. The core, surrounded by air, was then able to guide light. Two different applications were found for this fiber, as a temperature sensor and as an optical refractometer. In the last, the optical phase changes with the liquid refractive index. Two different types of fiber Bragg gratings were characterized in strain and temperature. Sensing structures obtained through the phase mask technique at the tip of an optical fiber were subjected to chemical etching. In this case, an excimer laser was used. Extremely thin fiber tips were obtained, with an ultra-high sensitivity to strain. The other technique employed to fabricate the fiber Bragg gratings was the point-by-point femtosecond laser inscription. In this case, the sensing elements are very stable at high temperatures and can be used to measure strain in harsh conditions. The employment of optical fiber lasers as sensing elements was also considered in this Thesis. Two laser cavities were studied, one based on the ring configuration and the other based on a figure-of-eight configuration. From these works, the quality of the laser emission, namely the signal-to-noise ratio, the reduced full-width at half maximum and the stability should be highlighted. These characteristics allowed the measurement of different physical parameters, such as strain, temperature and torsion. Lastly, the possibility to use microspheres as sensing elements was considered. Using the electric arc of a fusion splicer, it is possible to create microspheres at the tip of an optical fiber. Furthermore, with this technique it is chains of microspheres can be obtained, constituting Mach-Zehnder-type interferometers which are sensitive to physical parameters like strain and temperature. The preliminary results obtained by introducing silica microspheres in a support structure are also presented. In this case, the sensors were subjected to temperature variations. All the experimental work was combined with the respective theoretical considerations. Many questions have been raised with the course of this PhD, and there are still some without a definite answer. Thus, new research paths can be followed, having their basis grounded in the configurations here presented.

  10. Sources and diagnostics for attosecond science

    NASA Astrophysics Data System (ADS)

    Miranda, Miguel Nicolau da Costa Ribeiro de

    The work described in this PhD Thesis focuses on the post-processing of optical fibers and their enhancement as sensing element. Since the majority of sensors presented are based in Fabry-Perot interferometers, an historical overview of this category of optical fiber sensors is firstly presented. This review considers the works published since the early years, in the beginning of the 1980s, until the middle of 2015. The incorporation of microcavities at the tip of a single mode fiber was extensively studied, particularly for the measurement of nitrogen and methane gas pressure. These cavities were fabricated using hollow core silica tubes and a hollow core photonic crystal fiber. Following a different approach, the microcavities were incorporated between two sections of single mode fiber. In this case, the low sensitivity to temperature makes these microcavities highly desirable for the measurement of strain at high temperatures. Competences in post-processing techniques such as the chemical etching and the writing of periodical structures in the fiber core by means of an excimer or a femtosecond laser were also acquired in the course of the PhD programme. One of the works consisted in the design and manufacturing of a double clad optical fiber. The refractive index of the inner cladding was higher than the one of the outer cladding and the core. Thus, light was guided in the inner cladding instead of propagating in the core. This situation was overcome by applying chemical etching, thus removing the inner cladding. The core, surrounded by air, was then able to guide light. Two different applications were found for this fiber, as a temperature sensor and as an optical refractometer. In the last, the optical phase changes with the liquid refractive index. Two different types of fiber Bragg gratings were characterized in strain and temperature. Sensing structures obtained through the phase mask technique at the tip of an optical fiber were subjected to chemical etching. In this case, an excimer laser was used. Extremely thin fiber tips were obtained, with an ultra-high sensitivity to strain. The other technique employed to fabricate the fiber Bragg gratings was the point-by-point femtosecond laser inscription. In this case, the sensing elements are very stable at high temperatures and can be used to measure strain in harsh conditions. The employment of optical fiber lasers as sensing elements was also considered in this Thesis. Two laser cavities were studied, one based on the ring configuration and the other based on a figure-of-eight configuration. From these works, the quality of the laser emission, namely the signal-to-noise ratio, the reduced full-width at half maximum and the stability should be highlighted. These characteristics allowed the measurement of different physical parameters, such as strain, temperature and torsion. Lastly, the possibility to use microspheres as sensing elements was considered. Using the electric arc of a fusion splicer, it is possible to create microspheres at the tip of an optical fiber. Furthermore, with this technique it is chains of microspheres can be obtained, constituting Mach-Zehnder-type interferometers which are sensitive to physical parameters like strain and temperature. The preliminary results obtained by introducing silica microspheres in a support structure are also presented. In this case, the sensors were subjected to temperature variations. All the experimental work was combined with the respective theoretical considerations. Many questions have been raised with the course of this PhD, and there are still some without a definite answer. Thus, new research paths can be followed, having their basis grounded in the configurations here presented.

  11. Prototype Development of the GMT Fast Steering Mirror

    NASA Astrophysics Data System (ADS)

    Kim, Young-Soo; Koh, J.; Jung, H.; Jung, H.; Cho, M. K.; Park, W.; Yang, H.; Kim, H.; Lee, K.; Ahn, H.; Park, B.

    2013-06-01

    A Fast Steering Mirror (FSM) is going to be produced as a secondary mirror of the Giant Magellan Telescope (GMT). FSM is 3.2 m in diameter and the focal ratio is 0.65. It is composed of seven circular segments which match with the primary mirror segments. Each segment contains a light-weighted mirror whose diameter is 1.1 m. It also contains tip-tilt actuators which would compensate wind effect and structure jitter. An FSM prototype (FSMP) has been developed, which consists of a full-size off-axis mirror segment and a tip-tilt test-bed. The main purpose of the FSMP development is to achieve key technologies, such as fabrication of highly aspheric off-axis mirror and tip-tilt actuation. The development has been conducted by a consortium of five institutions in Korea and USA, and led by Korea Astronomy and Space Science Institute. The mirror was light-weighted and grinding of the front surface was finished. Polishing is in progress with computer generated hologram tests. The tip-tilt test-bed has been manufactured and assembled. Frequency tests are being performed and optical tilt set-up is arranged for visual demonstration. In this paper, we present progress of the prototype development, and future works.

  12. Local measurement and numerical modeling of mass/heat transfer from a turbine blade in a linear cascade with tip clearance

    NASA Astrophysics Data System (ADS)

    Jin, Peitong

    2000-11-01

    Local mass/heat transfer measurements from the turbine blade near-tip and the tip surfaces are performed using the naphthalene sublimation technique. The experiments are conducted in a linear cascade consisting of five high-pressure blades with a central test-blade configuration. The incoming flow conditions are close to those of the gas turbine engine environment (boundary layer displacement thickness is about 0.01 of chord) with an exit Reynolds number of 6.2 x 105. The effects of tip clearance level (0.86%--6.90% of chord), mainstream Reynolds number and turbulence intensity (0.2 and 12.0%) are investigated. Two methods of flow visualization---oil and lampblack, laser light sheet smoke wire---as well as static pressure measurement on the blade surface are used to study the tip leakage flow and vortex in the cascade. In addition, numerical modeling of the flow and heat transfer processes in the linear cascade with different tip clearances is conducted using commercial software incorporating advanced turbulence models. The present study confirms many important results on the tip leakage flow and vortex from the literature, contributes to the current understanding in the effects of tip leakage flow and vortex on local heat transfer from the blade near-tip and the tip surfaces, and provides detailed local and average heat/mass transfer data applicable to turbine blade tip cooling design.

  13. Tips for Teaching Birding.

    ERIC Educational Resources Information Center

    Burtch, Bob

    1986-01-01

    Provides descriptions of indoor and outdoor activities that can be used in teaching a unit on birds. Suggests techniques that can be helpful in bird identification. Includes a reference list of audiovisual materials, books, and field guides on birds. (ML)

  14. A Fan Concept to Meet the 2017 Noise Goals

    NASA Technical Reports Server (NTRS)

    Dittmar, James H.

    1998-01-01

    The National Aeronautics and Space Administration has established a goal of a 20 EPNdB reduction of aircraft noise by the year 2017. This paper proposes a fan concept for an engine that may meet this noise goal. The concept builds upon technology established during the Advanced Subsonic Technology Program which should show a 10 dB reduction potential. The new concept uses a two stage fan which allows low tip speed while still maintaining a reasonable total pressure rise across the two stages. The concept also incorporates many other noise reduction techniques in addition to low tip speed including a low number of exit guide vanes, swept and leaned guide vanes, a high subsonic Mach number inlet and syncrophased rotors to obtain active noise cancellation. The fan proposed in this paper is calculated to be able to achieve the 2017 noise goal.

  15. [Methods of resolution for haptic assistance during catheterization].

    PubMed

    Kern, T A; Herrmann, J; Klages, S; Meiss, T; Werthschützky, R

    2005-01-01

    During catheterization navigation within the patient is mainly dependent on a live x-ray image on the screen. Although methods for 3D visualisation and remote navigation of the catheter are discussed and tested still precise positioning is merely the result of intense training and a high skill and level of training of the performing surgeon. This article refers to a system which can be considered as an add-on for existing procedures of catheterization. It compromises of a miniaturised force sensor located at the tip of guide-wires whose prototype is shown here. The measured forces will be presented to the surgeon amplified by an external actuator described in this article. As a result a haptic perception of the forces between the tip of the guide-wire and the vessels walls will be available and enable the surgeon to gain an impression which is comparable to palpation of living vessels from the inside

  16. Teaching & Learning Tips 1: Teaching perspectives - an introduction.

    PubMed

    Rana, Jasmine; Burgin, Susan

    2017-11-01

    Challenge: Clinical and research responsibilities often leave little or no time to plan thoughtful teaching encounters with trainees. This "Teaching & Learning Tips" series is designed to be an accessible guide for dermatologists who want to improve their teaching skills. It is comprised of 12 articles about how to enhance teaching in various settings informed by research about how people learn and expert-derived or data-driven best practices for teaching. The series begins with a review of principles to optimize learning in any setting, including cognitive load theory, active learning strategies, and the impact of motivation and emotion on learning. It transitions into a practical "how to" guide format for common teaching scenarios in dermatology, such as lecturing, case-based teaching, and teaching procedures, among others. Herein, we kickoff the series by unpacking assumptions about teaching and learning. What does it mean to teach and learn? © 2017 The International Society of Dermatology.

  17. Magnetic guide-wire navigation in pulmonary and systemic arterial catheterization: initial experience in pigs.

    PubMed

    Grosse-Wortmann, Lars; Grabitz, Ralf; Seghaye, Marie-Christine

    2007-04-01

    Cardiovascular catheterization can be challenging whenever a stenosis or an abnormal vascular course interferes with probing the target vessel. This study addresses the feasibility of navigating a guide wire with a magnetic tip by an external magnetic field through pulmonary and systemic arteries in an experimental porcine model. We investigated six piglets using magnetic guide-wire navigation. Two pulmonary arteriograms were taken from different angles in order to reconstruct the three-dimensional vessel anatomy. A computer interface then calculated three-dimensional coordinates for the vessel in space. Using these coordinates, two external magnets were positioned to create magnetic vectors along the expected vessel course. Magnetically enabled guide wires were then navigated into the vessels using the magnetic field to orient the guide-wire tips. Aortic and renal branches were addressed in a similar fashion. Difficulty in reaching the target vessel was reflected by the number of attempts that were necessary. After 10 failed attempts, the maneuver was recorded to have failed. Thirty-five of 37 (94.6%) arteries with branches at acute angles were reached successfully using magnetic navigation. In two pigs, the left upper lobe artery could not be probed. Peripheral arteries of small diameter were easier to reach than large central arteries, requiring less attempts. Magnetic guide-wire navigation is feasible in the arteries of the lungs, the head and neck, and the kidneys. It is particularly useful in entering small arterial branches at acute angles and may facilitate interventional therapy in a variety of vascular diseases in children and adults.

  18. Therapeutic outcome of CT-guided radiofrequency ablation in patients with osteoid osteoma.

    PubMed

    Lassalle, Louis; Campagna, R; Corcos, G; Babinet, A; Larousserie, F; Stephanazzi, J; Feydy, A

    2017-07-01

    To assess the long-term outcome of computed tomography-guided radiofrequency ablation (CT-guided RFA) in patients with suspected osteoid osteoma (OO). Single-center retrospective study. Patients with clinical suspicion and imaging diagnosis of osteoid osteoma were treated by CT-guided RFA using the same device with either a 7- or 10-mm active tip electrode. Specific precautions were applied in case of articular or spinal OO. Patients were contacted by phone to evaluate the long-term outcome in terms of pain, ability to perform daily activities (including sports), and long-term complications. Success was defined as the absence of residual pain and ability to perform daily activities normally. From 2008 to 2015, 126 patients were treated by CT-guided RFA for OO in our institution. Mean patient age was 26.1 years (SD = 11, range 1-53); mean delay to diagnosis was 16.9 months (SD = 15.2, range 1-120). Among patients who answered the follow-up call (n = 88), the overall success rate was 94.3%: 79/88 (89.8%) had primary success of the procedure, and 4/88 (4.5%) had a secondary success (repeat-RFA after pain recurrence). Mean follow-up time was 34.6 months (SD = 24.7, range 3-90). Few complications occurred: two mild reversible peripheral nerve injuries, one brachial plexus neuropathy, one broken electrode tip fragment, and one muscular hematoma. Osteoid osteoma can be effectively and safely treated by CT-guided RFA using the presented ablation protocol. Beneficial effects of the treatment persist at long-term follow-up.

  19. A multiport MR-compatible neuroendoscope: spanning the gap between rigid and flexible scopes

    PubMed Central

    Manjila, Sunil; Mencattelli, Margherita; Rosa, Benoit; Price, Karl; Fagogenis, Georgios; Dupont, Pierre E.

    2017-01-01

    OBJECTIVE Rigid endoscopes enable minimally invasive access to the ventricular system; however, the operative field is limited to the instrument tip, necessitating rotation of the entire instrument and causing consequent tissue compression while reaching around corners. Although flexible endoscopes offer tip steerability to address this limitation, they are more difficult to control and provide fewer and smaller working channels. A middle ground between these instruments—a rigid endoscope that possesses multiple instrument ports (for example, one at the tip and one on the side)—is proposed in this article, and a prototype device is evaluated in the context of a third ventricular colloid cyst resection combined with septostomy. METHODS A prototype neuroendoscope was designed and fabricated to include 2 optical ports, one located at the instrument tip and one located laterally. Each optical port includes its own complementary metal-oxide semiconductor (CMOS) chip camera, light-emitting diode (LED) illumination, and working channels. The tip port incorporates a clear silicone optical window that provides 2 additional features. First, for enhanced safety during tool insertion, instruments can be initially seen inside the window before they extend from the scope tip. Second, the compliant tip can be pressed against tissue to enable visualization even in a blood-filled field. These capabilities were tested in fresh porcine brains. The image quality of the multiport endoscope was evaluated using test targets positioned at clinically relevant distances from each imaging port, comparing it with those of clinical rigid and flexible neuroendoscopes. Human cadaver testing was used to demonstrate third ventricular colloid cyst phantom resection through the tip port and a septostomy performed through the lateral port. To extend its utility in the treatment of periventricular tumors using MR-guided laser therapy, the device was designed to be MR compatible. Its functionality and compatibility inside a 3-T clinical scanner were also tested in a brain from a freshly euthanized female pig. RESULTS Testing in porcine brains confirmed the multiport endoscope’s ability to visualize tissue in a blood-filled field and to operate inside a 3-T MRI scanner. Cadaver testing confirmed the device’s utility in operating through both of its ports and performing combined third ventricular colloid cyst resection and septostomy with an endoscope rotation of less than 5°. CONCLUSIONS The proposed design provides freedom in selecting both the number and orientation of imaging and instrument ports, which can be customized for each ventricular pathological entity. The lightweight, easily manipulated device can provide added steerability while reducing the potential for the serious brain distortion that happens with rigid endoscope navigation. This capability would be particularly valuable in treating hydrocephalus, both primary and secondary (due to tumors, cysts, and so forth). Magnetic resonance compatibility can aid in endoscope-assisted ventricular aqueductal plasty and stenting, the management of multiloculated complex hydrocephalus, and postinflammatory hydrocephalus in which scarring obscures the ventricular anatomy. PMID:27581309

  20. Novel nano-OLED based probes for very high resolution optical microscopy

    NASA Astrophysics Data System (ADS)

    Zhao, Yiying

    Near-field scanning optical microscopy (NSOM) has been applied in the study of nanomaterials, microelectronics, photonics, plasmonics, cells, and molecules. However, conventional NSOM relies on optically pumped probes, suffering low optical transmission, heating of the tip, and poor reproducibility of probe fabrication, increasing the cost, impeding usability, reducing practical imaging resolution, and limiting NSOM's utility. In this thesis, I demonstrate a novel probe based on a nanoscale, electrically pumped organic light-emitting device (OLED) formed on the tip of a low-cost, commercially available atomic force microscopy (AFM) probe. I describe the structure, fabrication, and principles of this novel probe's operation, and discuss its potential to overcome the limitations of conventional NSOM probes. The broader significance of this work in the field of organic optoelectronics is also discussed. Briefly, OLEDs consist of organic thin films sandwiched between two electrodes. Under bias, electrons and holes are injected into the organic layers, leading to radiative recombination. Depositing a small molecular OLED in vacuum onto a pyramid-tipped AFM probe results in a laminar structure that is highly curved at the tip. Simple electrical modeling predicts concentration of electric field and localized electron injection into the organic layers at the tip, improving the local charge balance in an otherwise electron-starved OLED. Utilizing an "inverted" OLED structure (i.e. cathode on the "bottom"), light emission is localized to sub-200 nm sized, green light emitting regions on probe vertices; light output power in the range of 0.1-0.5 nanowatts was observed, comparable to that of typical fiber based NSOM probes but with greater power efficiency. Massive arrays of similar sub-micron OLEDs were also fabricated by depositing onto textured silicon substrates, demonstrating the superior scalability of the probe fabrication process (e.g. relative to pulled glass fibers). The investigation of the effect of non-planar substrate geometry on charge injection, transport and recombination provides broader insights into OLEDs made on rough substrates, general understanding of OLED operation (e.g. filamentary charge conduction) and degradation, and potentially helps to improve technologically important "inverted" OLED structures.

  1. 15. Photo copy of drawing, June 2, 1985, SAYBROOK BREAKWATER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Photo copy of drawing, June 2, 1985, SAYBROOK BREAKWATER LIGHT, SAYBROOK, CONNECTICUT, MODERNIZATION 1985: REMOVALS. U.S. Coast Guard Civil Engineering Unit, Warwick, RI - Saybrook Breakwater Light, South tip of west end of Saybrook Breakwater, Old Saybrook, Middlesex County, CT

  2. An optical fiber bundle sensor for tip clearance and tip timing measurements in a turbine rig.

    PubMed

    García, Iker; Beloki, Josu; Zubia, Joseba; Aldabaldetreku, Gotzon; Illarramendi, María Asunción; Jiménez, Felipe

    2013-06-05

    When it comes to measuring blade-tip clearance or blade-tip timing in turbines, reflective intensity-modulated optical fiber sensors overcome several traditional limitations of capacitive, inductive or discharging probe sensors. This paper presents the signals and results corresponding to the third stage of a multistage turbine rig, obtained from a transonic wind-tunnel test. The probe is based on a trifurcated bundle of optical fibers that is mounted on the turbine casing. To eliminate the influence of light source intensity variations and blade surface reflectivity, the sensing principle is based on the quotient of the voltages obtained from the two receiving bundle legs. A discrepancy lower than 3% with respect to a commercial sensor was observed in tip clearance measurements. Regarding tip timing measurements, the travel wave spectrum was obtained, which provides the average vibration amplitude for all blades at a particular nodal diameter. With this approach, both blade-tip timing and tip clearance measurements can be carried out simultaneously. The results obtained on the test turbine rig demonstrate the suitability and reliability of the type of sensor used, and suggest the possibility of performing these measurements in real turbines under real working conditions.

  3. An Optical Fiber Bundle Sensor for Tip Clearance and Tip Timing Measurements in a Turbine Rig

    PubMed Central

    García, Iker; Beloki, Josu; Zubia, Joseba; Aldabaldetreku, Gotzon; Illarramendi, María Asunción; Jiménez, Felipe

    2013-01-01

    When it comes to measuring blade-tip clearance or blade-tip timing in turbines, reflective intensity-modulated optical fiber sensors overcome several traditional limitations of capacitive, inductive or discharging probe sensors. This paper presents the signals and results corresponding to the third stage of a multistage turbine rig, obtained from a transonic wind-tunnel test. The probe is based on a trifurcated bundle of optical fibers that is mounted on the turbine casing. To eliminate the influence of light source intensity variations and blade surface reflectivity, the sensing principle is based on the quotient of the voltages obtained from the two receiving bundle legs. A discrepancy lower than 3% with respect to a commercial sensor was observed in tip clearance measurements. Regarding tip timing measurements, the travel wave spectrum was obtained, which provides the average vibration amplitude for all blades at a particular nodal diameter. With this approach, both blade-tip timing and tip clearance measurements can be carried out simultaneously. The results obtained on the test turbine rig demonstrate the suitability and reliability of the type of sensor used, and suggest the possibility of performing these measurements in real turbines under real working conditions. PMID:23739163

  4. Tip-Enhanced Raman Scattering Microscopy: A Step toward Nanoscale Control of Intrinsic Molecular Properties

    NASA Astrophysics Data System (ADS)

    Yano, Taka-aki; Hara, Masahiko

    2018-06-01

    Tip-enhanced Raman scattering microscopy, a family of scanning probe microscopy techniques, has been recognized as a powerful surface analytical technique with both single-molecule sensitivity and angstrom-scale spatial resolution. This review covers the current status of tip-enhanced Raman scattering microscopy in surface and material nanosciences, including a brief history, the basic principles, and applications for the nanoscale characterization of a variety of nanomaterials. The focus is on the recent trend of combining tip-enhanced Raman scattering microscopy with various external stimuli such as pressure, voltage, light, and temperature, which enables the local control of the molecular properties and functions and also enables chemical reactions to be induced on a nanometer scale.

  5. CAD/CAM-produced surgical guides: Optimizing the treatment workflow.

    PubMed

    Neugebauer, J; Kistler, F; Kistler, S; Züdorf, G; Freyer, D; Ritter, L; Dreiseidler, T; Kusch, J; Zöller, J E

    2011-01-01

    The increased availability of devices for 3D radiological diagnosis allows the more frequent use of CAD/CAM-produced surgical guides for implant placement. The conventional workflow requires a complex logistic chain which is time-consuming and costly. In a pilot study, the workflow of directly milled surgical guides was evaluated. These surgical guides were designed based on the fusion of an optical impression and the radiological data. The clinical use showed that the surgical guides could be accurately placed on the residual dentition without tipping movements. The conventional surgical guides were used as a control for the manual check of the deviation of the implant axis. The direct transfer of the digital planning data allows the fabrication of surgical guides in an external center without the need of physical transport, which reduces the logistic effort and expense of the central fabrication of surgical guides.

  6. Percutaneous Mesocaval Shunt Creation in a Patient with Chronic Portal and Superior Mesenteric Vein Thrombosis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bercu, Zachary L., E-mail: zachary.bercu@mountsinai.org; Sheth, Sachin B., E-mail: sachinsheth@gmail.com; Noor, Amir, E-mail: amir.noor@gmail.com

    The creation of a transjugular intrahepatic portosystemic shunt (TIPS) is a critical procedure for the treatment of recurrent variceal bleeding and refractory ascites in the setting of portal hypertension. Chronic portal vein thrombosis remains a relative contraindication to conventional TIPS and options are limited in this scenario. Presented is a novel technique for management of refractory ascites in a patient with hepatitis C cirrhosis and chronic portal and superior mesenteric vein thrombosis secondary to schistosomiasis and lupus anticoagulant utilizing fluoroscopically guided percutaneous mesocaval shunt creation.

  7. DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    Provides consumers with home energy and money savings tips such as insulation, weatherization, heating, cooling, water heating, energy efficient windows, landscaping, lighting, and energy efficient appliances.

  8. XML Schema Guide for Primary CDR Submissions

    EPA Pesticide Factsheets

    This document presents the extensible markup language (XML) schema guide for the Office of Pollution Prevention and Toxics’ (OPPT) e-CDRweb tool. E-CDRweb is the electronic, web-based tool provided by Environmental Protection Agency (EPA) for the submission of Chemical Data Reporting (CDR) information. This document provides the user with tips and guidance on correctly using the version 1.7 XML schema. Please note that the order of the elements must match the schema.

  9. Short Course in Highway Lighting.

    ERIC Educational Resources Information Center

    Federal Highway Administration (DOT), Washington, DC.

    This course guide in highway lighting includes an overview of trends in highway lighting, illustrated information on three light sources for today's luminaires, a reference guide to lamp classification, specifications for highway lighting equipment, and instructions for calculating appropriate use. Maintenance notes on highway illumination and…

  10. Polymer optical fiber compound parabolic concentrator tip for enhanced coupling efficiency for fluorescence based glucose sensors

    PubMed Central

    Hassan, Hafeez Ul; Nielsen, Kristian; Aasmul, Soren; Bang, Ole

    2015-01-01

    We demonstrate that the light excitation and capturing efficiency of fluorescence based fiber-optical sensors can be significantly increased by using a CPC (Compound Parabolic Concentrator) tip instead of the standard plane-cut tip. We use Zemax modelling to find the optimum CPC tip profile and fiber length of a polymer optical fiber diabetes sensor for continuous monitoring of glucose levels. We experimentally verify the improved performance of the CPC tipped sensor and the predicted production tolerances. Due to physical size requirements when the sensor has to be inserted into the body a non-optimal fiber length of 35 mm is chosen. For this length an average improvement in efficiency of a factor of 1.7 is experimentally demonstrated and critically compared to the predicted ideal factor of 3 in terms of parameters that should be improved through production optimization. PMID:26713213

  11. A nanoscale vacuum-tube diode triggered by few-cycle laser pulses

    NASA Astrophysics Data System (ADS)

    Higuchi, Takuya; Maisenbacher, Lothar; Liehl, Andreas; Dombi, Péter; Hommelhoff, Peter

    2015-02-01

    We propose and demonstrate a nanoscale vacuum-tube diode triggered by few-cycle near-infrared laser pulses. It represents an ultrafast electronic device based on light fields, exploiting near-field optical enhancement at surfaces of two metal nanotips. The sharper of the two tips displays a stronger field-enhancement, resulting in larger photoemission yields at its surface. One laser pulse with a peak intensity of 4.7 × 1011 W/cm2 triggers photoemission of ˜16 electrons from the sharper cathode tip, while emission from the blunter anode tip is suppressed by 19 dB to ˜0.2 electrons per pulse. Thus, the laser-triggered current between two tips exhibit a rectifying behavior, in analogy to classical vacuum-tube diodes. According to the kinetic energy of the emitted electrons and the distance between the tips, the total operation time of this laser-triggered nanoscale diode is estimated to be below 1 ps.

  12. Accurate real-time sensing tip for aqueous NO with optical fibers embedded in active hydrogel waveguide

    NASA Astrophysics Data System (ADS)

    Chung, Chieh-Wen; Tsai, May-Jywan; Lin, Peng-Wei; Huang, Ding-Wen; Wang, Kuan-Hsun; Chen, Yu-An; Meng, Hsin-Fei; Zan, Hsiao-Wen; Cheng, Henrich; Tong, Limin; Zhang, Lei; Horng, Sheng-Fu; Hung, Cheng-Hsiung

    2018-02-01

    A NO sensing tip is made by inserting two parallel optical fibers inside a poly 2-hydroxyethyl methacrylate (PolyHEMA) hydrogel waveguide mixed with the probe molecule 1, 2-Diaminoanthraquinone (DAQ). There is a length difference of 1 mm between the two fibers, and the light has to propagate through the difference from the short fiber to the long fiber. The total cross section area of the active hydrogel waveguide embedded with the fibers is only 3mm x 1.2 mm. For practical use the tip is housed in a needle for mechanical protection and the sensing tip is able to detect aqueous NO concentration around 1 μM with time resolution about 5 minutes. Such a sensing tip can be used to monitor the medical conditions inside the brain after a stroke or a brain injury.

  13. Physcomitrella patens: a model for tip cell growth and differentiation.

    PubMed

    Vidali, Luis; Bezanilla, Magdalena

    2012-12-01

    The moss Physcomitrella patens has emerged as an excellent model system owing to its amenability to reverse genetics. The moss gametophyte has three filamentous tissues that grow by tip growth: chloronemata, caulonemata, and rhizoids. Because establishment of the moss plant relies on this form of growth, it is particularly suited for dissecting the molecular basis of tip growth. Recent studies demonstrate that a core set of actin cytoskeletal proteins is essential for tip growth. Additional actin cytoskeletal components are required for modulating growth to produce caulonemata and rhizoids. Differentiation into these cell types has previously been linked to auxin, light and nutrients. Recent studies have identified that core auxin signaling components as well as transcription factors that respond to auxin or nutrient levels are required for tip-growing cell differentiation. Future studies may establish a connection between the actin cytoskeleton and auxin or nutrient-induced cell differentiation. Copyright © 2012 Elsevier Ltd. All rights reserved.

  14. Polymer optical fiber compound parabolic concentrator tip for enhanced coupling efficiency for fluorescence based glucose sensors.

    PubMed

    Hassan, Hafeez Ul; Nielsen, Kristian; Aasmul, Soren; Bang, Ole

    2015-12-01

    We demonstrate that the light excitation and capturing efficiency of fluorescence based fiber-optical sensors can be significantly increased by using a CPC (Compound Parabolic Concentrator) tip instead of the standard plane-cut tip. We use Zemax modelling to find the optimum CPC tip profile and fiber length of a polymer optical fiber diabetes sensor for continuous monitoring of glucose levels. We experimentally verify the improved performance of the CPC tipped sensor and the predicted production tolerances. Due to physical size requirements when the sensor has to be inserted into the body a non-optimal fiber length of 35 mm is chosen. For this length an average improvement in efficiency of a factor of 1.7 is experimentally demonstrated and critically compared to the predicted ideal factor of 3 in terms of parameters that should be improved through production optimization.

  15. An investigation of the potential of rapid prototyping technology for image‐guided surgery

    PubMed Central

    Rajon, Didier A.; Bova, Frank J.; Bhasin, R. Rick; Friedman, William A.

    2006-01-01

    Image‐guided surgery can be broken down into two broad categories: frame‐based guidance and frameless guidance. In order to reduce both the invasive nature of stereotactic guidance and the cost in equipment and time, we have developed a new guidance technique based on rapid prototyping (RP) technology. This new system first builds a computer model of the patient anatomy and then fabricates a physical reference frame that provides a precise and unique fit to the patient anatomy. This frame incorporates a means of guiding the surgeon along a preplanned surgical trajectory. This process involves (1) obtaining a high‐resolution CT or MR scan, (2) building a computer model of the region of interest, (3) developing a surgical plan and physical guide, (4) designing a frame with a unique fit to the patient's anatomy with a physical linkage to the surgical guide, and (5) fabricating the frame using an RP unit. Software was developed to support these processes. To test the accuracy of this process, we first scanned and reproduced a plastic phantom fabricated to validate the system's ability to build an accurate virtual model. A target on the phantom was then identified, a surgical approach planned, a surgical guide designed, and the accuracy and precision of guiding a probe to that target were determined. Steps 1 through 5 were also evaluated using a head phantom. The results show that the RP technology can replicate an object from CT scans with submillimeter resolution. The fabricated reference frames, when positioned on the surface of the phantom and used to guide a surgical probe, can position the probe tip with an accuracy of 1.7 mm at the probe tip. These results demonstrate that the RP technology can be used for the fabrication of customized positioning frames for use in image‐guided surgery. PACS number: 87.57.Gg PMID:17533357

  16. Small, Lightweight Inspection Robot With 12 Degrees Of Freedom

    NASA Technical Reports Server (NTRS)

    Lee, Thomas S.; Ohm, Timothy R.; Hayati, Samad

    1996-01-01

    Small serpentine robot weighs only 6 lbs. and has link diameter of 1.5 in. Designed to perform inspections. Multiple degrees of freedom enables it to reach around obstacles and through small openings into simple or complexly shaped confined spaces to positions where difficult or impossible to perform inspections by other means. Fiber-optic borescope incorporated into robot arm, with inspection tip of borescope located at tip of arm. Borescope both conveys light along robot arm to illuminate scene inspected at tip and conveys image of scene back along robot arm to external imaging equipment.

  17. Quick Tips for Buying Medicines Over the Internet: A Consumer Safety Guide

    MedlinePlus

    ... Laser Products Other Resources State Pharmacy Boards Federal Trade Commission U.S. Customs and Border Protection Spotlight A ... Products Advisory Committees Regulatory Information Safety Emergency Preparedness International Programs News & Events Training & Continuing Education Inspections & Compliance ...

  18. A Design Thinking Approach to Teaching Knowledge Management

    ERIC Educational Resources Information Center

    Wang, Shouhong; Wang, Hai

    2008-01-01

    Pedagogies for knowledge management courses are still undeveloped. This Teaching Tip introduces a design thinking approach to teaching knowledge management. An induction model used to guide students' real-life projects for knowledge management is presented. (Contains 1 figure.)

  19. Light distributor for endoscopic photochemotherapy of tumors.

    PubMed

    Lenz, P

    1987-10-15

    This device is fixed to the extremity of an optical fiber and permits light to spread over tumors situated inside hollow organs accessible by endoscopes. Compared to currently used diffusing tips, light distributors have several advantages, in particular precise matching of the irradiated area to the target area, high transmission efficiency, high power density favoring therapeutically relevant hyperthermia, and great mechanical resistance. The clinical usefulness of light distributors has been demonstrated.

  20. Tips for Energy Savers In and Around the Home, On the Road, In the Marketplace. Don't Be Fuelish.

    ERIC Educational Resources Information Center

    Federal Energy Administration, Washington, DC.

    This pamphlet presents simple suggestions for energy conservation. Sections include: (1) In and around the home; (2) Using the family car; and (3) In the marketplace. The suggestions given are mostly common sense tips like dressing appropriately for either hot or cold weather, use electrical appliances and lights sparingly and at off-peak times,…

  1. Illumination of interior spaces by bended hollow light guides: Application of the theoretical light propagation method

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Darula, Stanislav; Kocifaj, Miroslav; Kittler, Richard

    2010-12-15

    To ensure comfort and healthy conditions in interior spaces the thermal, acoustics and daylight factors of the environment have to be considered in the building design. Due to effective energy performance in buildings the new technology and applications also in daylight engineering are sought such as tubular light guides. These allow the transport of natural light into the building core reducing energy consumption. A lot of installations with various geometrical and optical properties can be applied in real buildings. The simplest set of tubular light guide consists of a transparent cupola, direct tube with high reflected inner surface and amore » ceiling cover or diffuser redistributing light into the interior. Such vertical tubular guide is often used on flat roofs. When the roof construction is inclined a bend in the light guide system has to be installed. In this case the cupola is set on the sloped roof which collects sunlight and skylight from the seen part of the sky hemisphere as well as that reflected from the ground and opposite facades. In comparison with the vertical tube some additional light losses and distortions of the propagated light have to be expected in bended tubular light guides. Recently the theoretical model of light propagation was already published and its applications are presented in this study solving illuminance distributions on the ceiling cover interface and further illuminance distribution on the working plane in the interior. (author)« less

  2. The phototransduction machinery in the rod outer segment has a strong efficacy gradient

    PubMed Central

    Mazzolini, Monica; Facchetti, Giuseppe; Andolfi, Laura; Proietti Zaccaria, Remo; Tuccio, Salvatore; Treu, Johannes; Altafini, Claudio; Di Fabrizio, Enzo M.; Lazzarino, Marco; Rapp, Gert; Torre, Vincent

    2015-01-01

    Rod photoreceptors consist of an outer segment (OS) and an inner segment. Inside the OS a biochemical machinery transforms the rhodopsin photoisomerization into electrical signal. This machinery has been treated as and is thought to be homogenous with marginal inhomogeneities. To verify this assumption, we developed a methodology based on special tapered optical fibers (TOFs) to deliver highly localized light stimulations. By using these TOFs, specific regions of the rod OS could be stimulated with spots of light highly confined in space. As the TOF is moved from the OS base toward its tip, the amplitude of saturating and single photon responses decreases, demonstrating that the efficacy of the transduction machinery is not uniform and is 5–10 times higher at the base than at the tip. This gradient of efficacy of the transduction machinery is attributed to a progressive depletion of the phosphodiesterase along the rod OS. Moreover we demonstrate that, using restricted spots of light, the duration of the photoresponse along the OS does not increase linearly with the light intensity as with diffuse light. PMID:25941368

  3. Use of an angiographic catheter to facilitate fluoroscopy-guided percutaneous renal access in cases with diffuse contrast extravasation.

    PubMed

    Giannakopoulos, Stilianos; Bantis, Athanasios; Kalaitzis, Christos; Touloupidis, Stavros

    2010-10-01

    Occasionally during percutaneous surgery, significant contrast extravasation obscures the field, making fluoroscopic access no longer feasible. Herein, we describe a salvage technique. The cystoscopically placed, open-end ureteral catheter is exchanged with an angled-tip angiographic catheter. With the aid of a guidewire and under fluoroscopic guidance, the tip of the catheter is placed in a posterior calix. The "bull's eye" technique is then applied to direct the needle into the tip of the catheter. This technique was used in four cases over a 7-year period. Successful access was accomplished in all cases through a middle or upper calix. The catheter serves as a target for providing access to the renal collecting system and facilitates final tract dilatation.

  4. Flexible, liquid core light guide with focusing and light shaping attachments

    DOEpatents

    Wojcik, Randolph Frank; Majewski, Stanislaw; Zorn, Carl John; Kross, Brian

    1999-01-01

    A liquid light guide system for ultraviolet light is disclosed that has a light shaping arrangement for the emitted light, a stable liquid core and sheath and reliable and effective end closures. The end closures include a metal crimping arrangement that utilizes two layers of deformable materials to prevent cracking of endplugs.

  5. Resonant scattering of light from a glass/Ag/MgF2/air system with rough interfaces and supporting guided modes in attenuated total reflection.

    PubMed

    Ramírez-Duverger, Aldo S; Gaspar-Armenta, Jorge A; García-Llamas, Raúl

    2003-08-01

    We report experimental results of the resonant scattering of light from a prism-glass/Ag/MgF2/air system with use of the attenuated total reflection technique for p and s polarized light. Two MgF2 film thicknesses were used. The system with the thinner dielectric layer supports two transverse magnetic (TM) and two transverse electric (TE) guided modes at a wavelength of 632.8 nm, and the system with the thicker dielectric layer supports three TM and three TE guided modes. In both cases we found dips in the specular reflection as a function of incident angle that is due to excitation of guided modes in the MgF2 film. The scattered light shows peaks at angles corresponding to the measured excitation of the guided modes. These peaks are due to single-order scattering and occur for any angle of the incident light. All features in the scattering response are enhanced in resonance conditions, and the efficiency of injecting light into the guide is reduced.

  6. Filter presence and tipping paper color influence consumer perceptions of cigarettes.

    PubMed

    O'Connor, Richard J; Bansal-Travers, Maansi; Cummings, K Michael; Hammond, David; Thrasher, James F; Tworek, Cindy

    2015-12-22

    Cigarettes are marketed in a wide array of packaging and product configurations, and these may impact consumers' perceptions of product health effects and attractiveness. Filtered cigarettes are typically perceived as less hazardous and white tipping paper (as opposed to cork) often conveys 'lightness'. This study examined cigarette-related perceptions among 1220 young adult (age 18-35) current, ever, and never smokers recruited from three eastern U.S. cities (Buffalo NY, Columbia SC, Morgantown WV). Participants rated three cigarette sticks: two filtered cigarettes 85 mm in length, differing only in tipping paper color (cork versus white), and an unfiltered 70 mm cigarette. Overall, the cork-tipped cigarette was most commonly selected on taste and attractiveness, the white-tipped on least dangerous, and the unfiltered on most dangerous. Current smokers were more likely to select white-tipped (OR = 1.98) and cork-tipped (OR = 3.42) cigarettes, while ever smokers more commonly selected the cork-tipped (OR = 1.96), as most willing to try over the other products. Those willing to try the filtered white-tipped cigarette were more likely to have rated that cigarette as best tasting (OR = 11.10), attracting attention (OR = 17.91), and lowest health risk (OR = 1.94). Similarly, those willing to try cork tipped or unfiltered cigarettes rated those as best testing, attracting attention, and lowest health risk, respectively. Findings from this study demonstrate that consumer product perceptions can be influenced by elements of cigarette design, such as the presence and color of the filter tip.

  7. Characterizing nanoscale scanning probes using electron microscopy: A novel fixture and a practical guide

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jacobs, Tevis D. B., E-mail: tjacobs@pitt.edu; Wabiszewski, Graham E.; Goodman, Alexander J.

    2016-01-15

    The nanoscale geometry of probe tips used for atomic force microscopy (AFM) measurements determines the lateral resolution, contributes to the strength of the tip-surface interaction, and can be a significant source of uncertainty in the quantitative analysis of results. While inverse imaging of the probe tip has been used successfully to determine probe tip geometry, direct observation of the tip profile using electron microscopy (EM) confers several advantages: it provides direct (rather than indirect) imaging, requires fewer algorithmic parameters, and does not require bringing the tip into contact with a sample. In the past, EM-based observation of the probe tipmore » has been achieved using ad hoc mounting methods that are constrained by low throughput, the risk of contamination, and repeatability issues. We report on a probe fixture designed for use in a commercial transmission electron microscope that enables repeatable mounting of multiple AFM probes as well as a reference grid for beam alignment. This communication describes the design, fabrication, and advantages of this probe fixture, including full technical drawings for machining. Further, best practices are discussed for repeatable, non-destructive probe imaging. Finally, examples of the fixture’s use are described, including characterization of common commercial AFM probes in their out-of-the-box condition.« less

  8. Axon guidance molecules in vascular patterning.

    PubMed

    Adams, Ralf H; Eichmann, Anne

    2010-05-01

    Endothelial cells (ECs) form extensive, highly branched and hierarchically organized tubular networks in vertebrates to ensure the proper distribution of molecular and cellular cargo in the vertebrate body. The growth of this vascular system during development, tissue repair or in disease conditions involves the sprouting, migration and proliferation of endothelial cells in a process termed angiogenesis. Surprisingly, specialized ECs, so-called tip cells, which lead and guide endothelial sprouts, share many feature with another guidance structure, the axonal growth cone. Tip cells are motile, invasive and extend numerous filopodial protrusions sensing growth factors, extracellular matrix and other attractive or repulsive cues in their tissue environment. Axonal growth cones and endothelial tip cells also respond to signals belonging to the same molecular families, such as Slits and Roundabouts, Netrins and UNC5 receptors, Semaphorins, Plexins and Neuropilins, and Eph receptors and ephrin ligands. Here we summarize fundamental principles of angiogenic growth, the selection and function of tip cells and the underlying regulation by guidance cues, the Notch pathway and vascular endothelial growth factor signaling.

  9. Quick Guide to Health Literacy and Older Adults

    MedlinePlus

    ... starter tips Resources Additional Resources Cultural Competence Health Literacy Older Adults Plain Language Visual Impairment Web sites Content last updated: October 30, 2007 skip to navigation | skip to content ACCESSIBILITY | FREEDOM OF INFORMATION ACT | PRIVACY POLICY | CONTACT US Office of Disease ...

  10. Wavefront error budget development for the Thirty Meter Telescope laser guide star adaptive optics system

    NASA Astrophysics Data System (ADS)

    Gilles, Luc; Wang, Lianqi; Ellerbroek, Brent

    2008-07-01

    This paper describes the modeling effort undertaken to derive the wavefront error (WFE) budget for the Narrow Field Infrared Adaptive Optics System (NFIRAOS), which is the facility, laser guide star (LGS), dual-conjugate adaptive optics (AO) system for the Thirty Meter Telescope (TMT). The budget describes the expected performance of NFIRAOS at zenith, and has been decomposed into (i) first-order turbulence compensation terms (120 nm on-axis), (ii) opto-mechanical implementation errors (84 nm), (iii) AO component errors and higher-order effects (74 nm) and (iv) tip/tilt (TT) wavefront errors at 50% sky coverage at the galactic pole (61 nm) with natural guide star (NGS) tip/tilt/focus/astigmatism (TTFA) sensing in J band. A contingency of about 66 nm now exists to meet the observatory requirement document (ORD) total on-axis wavefront error of 187 nm, mainly on account of reduced TT errors due to updated windshake modeling and a low read-noise NGS wavefront sensor (WFS) detector. A detailed breakdown of each of these top-level terms is presented, together with a discussion on its evaluation using a mix of high-order zonal and low-order modal Monte Carlo simulations.

  11. Variation in human fungiform taste bud densities among regions and subjects.

    PubMed

    Miller, I J

    1986-12-01

    Taste sensitivity is known to vary among regions of the tongue and between subjects. The distribution of taste buds on the human tongue is examined in this report to determine if interregional and intersubject variation of taste bud density might account for some of the variation in human taste sensitivity. The subjects were ten males, aged 22-80 years, who died from acute trauma or an acute cardiovascular episode. Specimens were obtained as anatomical gifts or from autopsy. A sample of tissue about 1 cm2 was taken from the tongue tip and midlateral region; frozen sections were prepared for light microscopy; and serial sections were examined by light microscopy to count the taste buds. The average taste bud (tb) density on the tongue tip was 116 tb/cm2 with a range from 3.6 to 514 among subjects. The number of gustatory papillae on the tip averaged 24.5 papillae/cm2 with a range from 2.4 to 80. Taste bud density in the midregion averaged 25.2 tb/cm2 (range: 0-85.9), and the mean number of gustatory papillae was 8.25/cm2 (range: 0-28). The mean number of taste buds per papilla was 3.8 +/- 2.2 (s.d.) on the tip and 2.6 +/- 1.5 (s.d.) on the midregion. Subjects with the highest taste bud densities on the tip also had the highest densities in the midregion and the highest number of taste buds per papilla. Taste bud density was 4.6 times higher on the tip than the midregion, which probably accounts for some of the regional difference in taste sensitivity.(ABSTRACT TRUNCATED AT 250 WORDS)

  12. Using the Galileoscope in Public Outreach Programs In the United States and Chile

    NASA Astrophysics Data System (ADS)

    Sparks, Robert T.; Pompea, Stephen M.; Seguel, Juan C.; Munizaga, Daniel A.; Opazo, Leonor; Walker, Constance Elaine; Tresch Fienberg, Richard; Arion, Douglas N.

    2015-08-01

    The Galileoscope was developed by a team of educators, astronomers and optical engineers as one of the cornerstone projects for the International Year of Astronomy 2009 (IYA). Over 230,000 Galileoscopes have been distributed.The National Optical Astronomy Observatory (NOAO) has developed a variety of educational materials to accompany the Galileoscope. The Galileoscope Optics Guide contains a variety of experiments and demonstrations (adapted from the National Science Foundation funded Hands-On Optics program) to help students understand how a telescope focuses light and produces an image. The Teaching With Telescopes kit developed at NOAO contains a variety of materials teachers can use to teach about light and optics. The Teaching With Telescopes kit is a basis for teacher professional development. The Galileoscope Observing Guide (updated annually) contains a variety of observing tips and information on the best objects to observe with the Galileoscope.NOAO has used Galileoscopes in a wide variety of educational environments. NOAO received a grant from Science Foundation Arizona to bring the Hands-On Optics program to Boys and Girls Clubs in Arizona. All the Boys and Girls Clubs received Galileoscopes as part of the grant. Edelman Financial made a donation that allowed us to distribute 15,000 Galileoscopes to Project ASTRO sites, members of the National Earth Science Teacher’s Association and individual teachers. Science Foundation Arizona partnered with NOAO in the Arizona Galileoscope program to conduct star parties in Yuma, Flagstaff, Safford, Globe and Payson. NOAO partnered with Raytheon in the MathMovesU program to build Galileoscopes with over 2,000 students in Tucson. NOAO has used Galileoscopes in professional development workshops with teachers at meetings including the American Astronomical Society, the Astronomical Society of the Pacific, and the National Science Teachers Association.

  13. Full scale visualization of the wing tip vortices generated by a typical agricultural aircraft

    NASA Technical Reports Server (NTRS)

    Cross, E. J., Jr.; Bridges, P.; Brownlee, J. A.; Liningston, W. W.

    1980-01-01

    The trajectories of the wing tip vortices of a typical agricultural aircraft were experimentally determined by flight test. A flow visualization method, similar to the vapor screen method used in wind tunnels, was used to obtain trajectory data for a range of flight speeds, airplane configurations, and wing loadings. Detailed measurements of the spanwise surface pressure distribution were made for all test points. Further, a powered 1/8 scale model of the aircraft was designed, built, and used to obtain tip vortex trajectory data under conditions similar to that of the full-scale test. The effects of light wind on the vortices were demonstrated, and the interaction of the flap vortex and the tip vortex was clearly shown in photographs and plotted trajectory data.

  14. XML Schema Guide for Secondary CDR Submissions

    EPA Pesticide Factsheets

    This document presents the extensible markup language (XML) schema guide for the Office of Pollution Prevention and Toxics’ (OPPT) e-CDRweb tool. E-CDRweb is the electronic, web-based tool provided by Environmental Protection Agency (EPA) for the submission of Chemical Data Reporting (CDR) information. This document provides the user with tips and guidance on correctly using the version 1.1 XML schema for the Joint Submission Form. Please note that the order of the elements must match the schema.

  15. Transperineal prostate biopsy under magnetic resonance image guidance: a needle placement accuracy study.

    PubMed

    Blumenfeld, Philip; Hata, Nobuhiko; DiMaio, Simon; Zou, Kelly; Haker, Steven; Fichtinger, Gabor; Tempany, Clare M C

    2007-09-01

    To quantify needle placement accuracy of magnetic resonance image (MRI)-guided core needle biopsy of the prostate. A total of 10 biopsies were performed with 18-gauge (G) core biopsy needle via a percutaneous transperineal approach. Needle placement error was assessed by comparing the coordinates of preplanned targets with the needle tip measured from the intraprocedural coherent gradient echo images. The source of these errors was subsequently investigated by measuring displacement caused by needle deflection and needle susceptibility artifact shift in controlled phantom studies. Needle placement error due to misalignment of the needle template guide was also evaluated. The mean and standard deviation (SD) of errors in targeted biopsies was 6.5 +/- 3.5 mm. Phantom experiments showed significant placement error due to needle deflection with a needle with an asymmetrically beveled tip (3.2-8.7 mm depending on tissue type) but significantly smaller error with a symmetrical bevel (0.6-1.1 mm). Needle susceptibility artifacts observed a shift of 1.6 +/- 0.4 mm from the true needle axis. Misalignment of the needle template guide contributed an error of 1.5 +/- 0.3 mm. Needle placement error was clinically significant in MRI-guided biopsy for diagnosis of prostate cancer. Needle placement error due to needle deflection was the most significant cause of error, especially for needles with an asymmetrical bevel. (c) 2007 Wiley-Liss, Inc.

  16. Comparison of the heat generation of light curing units.

    PubMed

    Bagis, Bora; Bagis, Yildirim; Ertas, Ertan; Ustaomer, Seda

    2008-02-01

    The aim of this study was to evaluate the heat generation of three different types of light curing units. Temperature increases were recorded from a distance of 1 mm from a thermocouple to the tip of three different types of light curing units including one quartz-tungsten halogen (QTH), one plasma arc (PAC), and one light emitting diode (LED) unit. An experimental model was designed to fix the 1 mm distance between the tip of the light curing units and the thermocouple wire. Temperature changes were recorded in 10 second intervals up to 40 seconds. (10, 20, 30, and 40 seconds). Temperature measurements were repeated three times for every light curing unit after a one hour standby period. Statistical analysis of the results was performed using the analysis of variance (ANOVA) and the Bonferroni Test. The highest temperature rises (54.4+/-1.65 degrees C) occurred during activation of a PAC light curing unit for every test period (p<.05). The least temperature increase (11.8+/-1.3 degrees C) occurred with a LED curing unit for each tested period except for the measurement of the temperature rise using the QTH curing unit at the tenth second interval (p<.05). These results indicate the choice of light activation unit and curing time is important when polymerizing light activated resin based restorations to avoid any thermal damage to the pulp.

  17. Optical characterization of a light guide for the polymerization of root canal fillers: preliminary results

    NASA Astrophysics Data System (ADS)

    Munin, Egberto; Lupato Conrado, Luis A.; Alves, Leandro P.; Zangaro, Renato A.

    2004-05-01

    The sealing cements used in endodontics are commonly of the type activated by chemical reactions. During polymerization, mechanical contractions are not uncommon, leading to non-perfect sealing or treatment failure. Photopolymerizable cements usually presents superior performance as compared to those chemically activated. However, difficulties in carrying-up the light to difficult-to-reach regions like the dental apex preclude those material of being accepted in the dental office routine. Recently, a novel technique for the light curing of photopolymerizable cements in endodontic applications has been proposed. Such a technique makes use of a polymeric light guide to deliver the curing light to the apex region, for a single step polymerization of the canal filler. For this work, a 28 mm long polymer light-guide, has been produced. The polymer surface was roughened to produce light scattering and allow the light to escape from the guide. The light scattering profile along the body of the guide is an important property for the proposed application. We used an integrating sphere to measure the irradiation profile for the proposed endodontic device. It was found that the experimental data for the amount of light coupled into the integrating sphere as a function of the length of the cone inside the sphere fits to a double exponential model.

  18. Buder revisited: cell and organ polarity during phototropism.

    PubMed

    Nick, P; Furuya, M

    1996-10-01

    The induction of a radial polarity by environmental stimuli was studied at the cellular and organ levels, with phototropism chosen as a model. The light gradient acting on the whole coleoptile was opposed to the light direction acting upon individual cells in the classical Buder experiment, irradiating from the inside out. Alternatively, the stimulus was administered to the coleoptile tip with a microbeam-irradiation device. Tropistic curvature was assayed as a marker for the response of the whole organ, whereas cell elongation and the orientation of cortical microtubules were taken as markers for the responses of individual cells. Upon tip irradiation, signals much faster than basipetal auxin transport migrate towards the base. The data are discussed in terms of an organ polarity that is the primary result of the asymmetric light signal and affects, in a second step, an endogenous radial polarity of epidermal cells.

  19. Flexible, liquid core light guide with focusing and light shaping attachments

    DOEpatents

    Wojcik, R.F.; Majewski, S.; Zorn, C.J.; Kross, B.

    1999-04-20

    A liquid light guide system for ultraviolet light is disclosed that has a light shaping arrangement for the emitted light, a stable liquid core and sheath and reliable and effective end closures. The end closures include a metal crimping arrangement that utilizes two layers of deformable materials to prevent cracking of endplugs. 19 figs.

  20. Frequency-dependent photothermal measurement of transverse thermal diffusivity of organic semiconductors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brill, J. W.; Shahi, Maryam; Yao, Y.

    2015-12-21

    We have used a photothermal technique, in which chopped light heats the front surface of a small (∼1 mm{sup 2}) sample and the chopping frequency dependence of thermal radiation from the back surface is measured with a liquid-nitrogen-cooled infrared detector. In our system, the sample is placed directly in front of the detector within its dewar. Because the detector is also sensitive to some of the incident light, which leaks around or through the sample, measurements are made for the detector signal that is in quadrature with the chopped light. Results are presented for layered crystals of semiconducting 6,13-bis(triisopropylsilylethynyl) pentacene (TIPS-pn)more » and for papers of cellulose nanofibrils coated with semiconducting poly(3,4-ethylene-dioxythiophene):poly(styrene-sulfonate) (NFC-PEDOT). For NFC-PEDOT, we have found that the transverse diffusivity, smaller than the in-plane value, varies inversely with thickness, suggesting that texturing of the papers varies with thickness. For TIPS-pn, we have found that the interlayer diffusivity is an order of magnitude larger than the in-plane value, consistent with previous estimates, suggesting that low-frequency optical phonons, presumably associated with librations in the TIPS side groups, carry most of the heat.« less

  1. Computational Investigation of Novel Tip Leakage Mitigation Methods for High Pressure Turbine Blades

    NASA Technical Reports Server (NTRS)

    Ibrahim, Mounir; Gupta, Abhinav; Shyam, Vikram

    2014-01-01

    This paper presents preliminary findings on a possible approach to reducing tip leakage losses. In this paper a computational study was conducted on the Energy Efficient Engine (EEE) High Pressure Turbine (HPT) rotor tip geometry using the commercial numerical solver ANSYS FLUENT. The flow solver was validated against aerodynamic data acquired in the NASA Transonic Turbine Blade Cascade facility. The scope of the ongoing study is to computationally investigate how the tip leakage and overall blade losses are affected by (1) injection from the tip near the pressure side, (2) injection from the tip surface at the camber line, and (3) injection from the tip surface into the tip separation bubble. The objective is to identify the locations on the tip surface at which to place appropriately configured blowing keeping in mind the film cooling application of tip blowing holes. The validation was conducted at Reynolds numbers of 85,000, 343,000, and 685,000 and at engine realistic flow conditions. The coolant injection simulations were conducted at a Reynolds number of 343,000 based on blade chord and inlet velocity and utilized the SST turbulence model in FLUENT. The key parameters examined are the number of jets, jet angle and jet location. A coolant to inlet pressure ratio of 1.0 was studied for angles of +30 deg, -30 deg, and 90 deg to the local free stream on the tip. For the 3 hole configuration, 3 holes spaced 3 hole diameters apart with length to diameter ratio of 1.5 were used. A simulation including 11 holes along the entire mean camber line is also presented (30 deg toward suction side). In addition, the effect of a single hole is also compared to a flat tip with no injection. The results provide insight into tip flow control methods and can be used to guide further investigation into tip flow control. As noted in past research it is concluded that reducing leakage flow is not necessarily synonymous with reducing losses due to leakage.

  2. Computational Investigation of Novel Tip Leakage Mitigation Methods for High Pressure Turbine Blades

    NASA Technical Reports Server (NTRS)

    Ibrahim, Mounir; Gupta, Abhinav; Shyam, Vikram

    2014-01-01

    This paper presents preliminary findings on a possible approach to reducing tip leakage losses. In this paper a computational study was conducted on the EEE (Energy Efficient Engine) HPT (High Pressure Turbine) rotor tip geometry using the commercial numerical solver ANSYS FLUENT. The flow solver was validated against aerodynamic data acquired in the NASA Transonic Turbine Blade Cascade facility. The scope of the ongoing study is to computationally investigate how the tip leakage and overall blade losses are affected by 1. injection from the tip near the pressure side, 2. injection from the tip surface at the camber line, and 3. injection from the tip surface into the tip separation bubble. The objective is to identify the locations on the tip surface at which to place appropriately configured blowing keeping in mind the film cooling application of tip blowing holes. The validation was conducted at Reynolds numbers of 85,000, 343,000 and 685,000 and at engine realistic flow conditions. The coolant injection simulations were conducted at a Reynolds number of 343,000 based on blade chord and inlet velocity and utilized the SST turbulence model in FLUENT. The key parameters examined are the number of jets, jet angle and jet location. A coolant to inlet pressure ratio of 1.0 was studied for angles of +30 deg., -30 deg. and 90 deg. to the local free stream on the tip. For the 3 hole configuration, 3 holes spaced 3 hole diameters apart with length to diameter ratio of 1.5 were used. A simulation including 11 holes along the entire mean camber line is also presented (30 degrees toward suction side). In addition, the effect of a single hole is also compared to a flat tip with no injection. The results provide insight into tip flow control methods and can be used to guide further investigation into tip flow control. As noted in past research it is concluded that reducing leakage flow is not necessarily synonymous with reducing losses due to leakage.

  3. Ellipsometry-like analysis of polarization state for micro cracks using stress-induced light scattering method

    NASA Astrophysics Data System (ADS)

    Sakata, Yoshitaro; Terasaki, Nao; Sakai, Kazufumi; Nonaka, Kazuhiro

    2016-03-01

    Fine polishing techniques, such as chemical mechanical polishing (CMP), are important to glass substrate manufacturing. When these techniques involve mechanical interaction in the form of friction between the abrasive and the substrate surface during polishing, latent flaws may form on the product. Fine polishing induced latent flaws in glass substrates may become obvious during a subsequent cleaning process if the glass surface is eroded away by chemical interaction with a cleaning liquid. Thus, latent flaws reduce product yield. A novel technique (the stress-induced light scattering method; SILSM) which was combined with light scattering method and stress effects was proposed for inspecting surface to detect polishing induced latent flaws. This method is able to distinguish between latent flaws and tiny particles on the surface. In this method, an actuator deforms a sample inducing stress effects around the tip of a latent flaw caused by the deformation, which in turn changes the refractive index of the material around the tip of the latent flaw because of the photoelastic effect. A CCD camera detects this changed refractive index as variations in light-scattering intensity. In this study, the changes in reflection coefficients and polarization states after application of stress to a glass substrate were calculated and evaluated qualitatively using Jones matrix-like ellipsometry. As the results, it was shown that change in the polarization states around the tip of latent flaw were evaluated between before and after applied stress, qualitatively.

  4. Piezoresistor-equipped fluorescence-based cantilever probe for near-field scanning.

    PubMed

    Kan, Tetsuo; Matsumoto, Kiyoshi; Shimoyama, Isao

    2007-08-01

    Scanning near-field optical microscopes (SNOMs) with fluorescence-based probes are promising tools for evaluating the optical characteristics of nanoaperture devices used for biological investigations, and this article reports on the development of a microfabricated fluorescence-based SNOM probe with a piezoresistor. The piezoresistor was built into a two-legged root of a 160-microm-long cantilever. To improve the displacement sensitivity of the cantilever, the piezoresistor's doped area was shallowly formed on the cantilever surface. A fluorescent bead, 500 nm in diameter, was attached to the bottom of the cantilever end as a light-intensity-sensitive material in the visible-light range. The surface of the scanned sample was simply detected by the probe's end being displaced by contact with the sample. Measuring displacements piezoresistively is advantageous because it eliminates the noise arising from the use of the optical-lever method and is free of any disturbance in the absorption or the emission spectrum of the fluorescent material at the probe tip. The displacement sensitivity was estimated to be 6.1 x 10(-6) nm(-1), and the minimum measurable displacement was small enough for near-field measurement. This probe enabled clear scanning images of the light field near a 300 x 300 nm(2) aperture to be obtained in the near-field region where the tip-sample distance is much shorter than the light wavelength. This scanning result indicates that the piezoresistive way of tip-sample distance regulation is effective for characterizing nanoaperture optical devices.

  5. Approaching total absorption of graphene strips using a c-Si subwavelength periodic membrane

    NASA Astrophysics Data System (ADS)

    Sang, Tian; Wang, Rui; Li, Junlang; Zhou, Jianyu; Wang, Yueke

    2018-04-01

    Approaching total absorption of graphene strips at near infrared using a crystalline-silicon (c-Si) subwavelength periodic membrane (SPM) is presented. The absorption in graphene strips in a c-Si SPM is enhanced by a resonant tip, which is resulted from the coupling between the guided mode and the radiation mode through symmetry breaking of the structure at near-normal incidence. The enhancement of the electric field intensity is increased 1939 times and the group velocity of light is decreased to 3.55 ×10-4c at resonance, and 99.3% absorption in graphene strips can be achieved by critical coupling at the incident angle of 2°. High absorption of the graphene strips can be maintained as the etching thickness, the strip width, and the period are altered. When this type of c-Si SPM with graphene strips is used in refractive index sensors, it shows excellent sensing properties due to its stable near-unity absorption.

  6. HIGH-SPEED IMAGING AND WAVEFRONT SENSING WITH AN INFRARED AVALANCHE PHOTODIODE ARRAY

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baranec, Christoph; Atkinson, Dani; Hall, Donald

    2015-08-10

    Infrared avalanche photodiode (APD) arrays represent a panacea for many branches of astronomy by enabling extremely low-noise, high-speed, and even photon-counting measurements at near-infrared wavelengths. We recently demonstrated the use of an early engineering-grade infrared APD array that achieves a correlated double sampling read noise of 0.73 e{sup −} in the lab, and a total noise of 2.52 e{sup −} on sky, and supports simultaneous high-speed imaging and tip-tilt wavefront sensing with the Robo-AO visible-light laser adaptive optics (AO) system at the Palomar Observatory 1.5 m telescope. Here we report on the improved image quality simultaneously achieved at visible andmore » infrared wavelengths by using the array as part of an image stabilization control loop with AO-sharpened guide stars. We also discuss a newly enabled survey of nearby late M-dwarf multiplicity, as well as future uses of this technology in other AO and high-contrast imaging applications.« less

  7. Fracture mechanics by three-dimensional crack-tip synchrotron X-ray microscopy

    PubMed Central

    Withers, P. J.

    2015-01-01

    To better understand the relationship between the nucleation and growth of defects and the local stresses and phase changes that cause them, we need both imaging and stress mapping. Here, we explore how this can be achieved by bringing together synchrotron X-ray diffraction and tomographic imaging. Conventionally, these are undertaken on separate synchrotron beamlines; however, instruments capable of both imaging and diffraction are beginning to emerge, such as ID15 at the European Synchrotron Radiation Facility and JEEP at the Diamond Light Source. This review explores the concept of three-dimensional crack-tip X-ray microscopy, bringing them together to probe the crack-tip behaviour under realistic environmental and loading conditions and to extract quantitative fracture mechanics information about the local crack-tip environment. X-ray diffraction provides information about the crack-tip stress field, phase transformations, plastic zone and crack-face tractions and forces. Time-lapse CT, besides providing information about the three-dimensional nature of the crack and its local growth rate, can also provide information as to the activation of extrinsic toughening mechanisms such as crack deflection, crack-tip zone shielding, crack bridging and crack closure. It is shown how crack-tip microscopy allows a quantitative measure of the crack-tip driving force via the stress intensity factor or the crack-tip opening displacement. Finally, further opportunities for synchrotron X-ray microscopy are explored. PMID:25624521

  8. GALACSI system design and analysis

    NASA Astrophysics Data System (ADS)

    Ströbele, S.; La Penna, P.; Arsenault, R.; Conzelmann, R. D.; Delabre, B.; Duchateau, M.; Dorn, R.; Fedrigo, E.; Hubin, N.; Quentin, J.; Jolley, P.; Kiekebusch, M.; Kirchbauer, J. P.; Klein, B.; Kolb, J.; Kuntschner, H.; Le Louarn, M.; Lizon, J. L.; Madec, P.-Y.; Pettazzi, L.; Soenke, C.; Tordo, S.; Vernet, J.; Muradore, R.

    2012-07-01

    GALACSI is one of the Adaptive Optics (AO) systems part of the ESO Adaptive Optics Facility (AOF). It will use the VLT 4-Laser Guide Stars system, high speed and low noise WaveFront Sensor cameras (<1e-, 1000Hz) the Deformable Secondary Mirror (DSM) and the SPARTA Real Time Computer to sharpen images and enhance faint object detectability of the MUSE Instrument. MUSE is an Integral Field Spectrograph working at wavelengths from 465nm to 930nm. GALACSI implements 2 different AO modes; in Wide Field Mode (WFM) it will perform Ground Layer AO correction and enhance the collected energy in a 0.2" by 0.2" pixel by a factor 2 at 750nm over a Field of View (FoV) of 1' by 1'. The 4 LGSs and one tip tilt reference star (R-mag <17.5) are located outside the MUSE FoV. Key requirements are to provide this performance and a very good image stability for a 1hour long integration time. In Narrow Field Mode (NFM) Laser Tomography AO will be used to reconstruct and correct the turbulence for the center field using the 4 LGSs at 15" off axis and the Near Infra Red (NIR) light of one reference star on axis for tip tilt and focus sensing. In NFM GALACSI will provide a moderate Strehl Ratio of 5% (goal 10%) at 650nm. The NFM hosts several challenges and many subsystems will be pushed to their limits. The opto mechanical design and error budgets of GALACSI is described here.

  9. Linear least squares approach for evaluating crack tip fracture parameters using isochromatic and isoclinic data from digital photoelasticity

    NASA Astrophysics Data System (ADS)

    Patil, Prataprao; Vyasarayani, C. P.; Ramji, M.

    2017-06-01

    In this work, digital photoelasticity technique is used to estimate the crack tip fracture parameters for different crack configurations. Conventionally, only isochromatic data surrounding the crack tip is used for SIF estimation, but with the advent of digital photoelasticity, pixel-wise availability of both isoclinic and isochromatic data could be exploited for SIF estimation in a novel way. A linear least square approach is proposed to estimate the mixed-mode crack tip fracture parameters by solving the multi-parameter stress field equation. The stress intensity factor (SIF) is extracted from those estimated fracture parameters. The isochromatic and isoclinic data around the crack tip is estimated using the ten-step phase shifting technique. To get the unwrapped data, the adaptive quality guided phase unwrapping algorithm (AQGPU) has been used. The mixed mode fracture parameters, especially SIF are estimated for specimen configurations like single edge notch (SEN), center crack and straight crack ahead of inclusion using the proposed algorithm. The experimental SIF values estimated using the proposed method are compared with analytical/finite element analysis (FEA) results, and are found to be in good agreement.

  10. Photonic jet etching: Justifying the shape of optical fiber tip

    NASA Astrophysics Data System (ADS)

    Abdurrochman, Andri; Zelgowski, Julien; Lecler, Sylvain; Mermet, Frédéric; Tumbelaka, Bernard; Fontaine, Joël

    2016-02-01

    Photonic jet (PJ) is a low diverging and highly concentrated beam in the shadow side of dielectric particle (cylinder or sphere). The concentration can be more than 200 times higher than the incidence wave. It is a non-resonance phenomenon in the near-field can propagate in a few wavelengths. Many potential applications have been proposed, including PJ etching. Hence, a guided-beam is considered increasing the PJ mobility control. While the others used a combination of classical optical fibers and spheres, we are concerned on a classical optical fiber with spherical tip to generate the PJ. This PJ driven waveguide has been realized using Gaussian mode beam inside the core. It has different variable parameters compared to classical PJ, which will be discussed in correlation with the etching demonstrations. The parameters dependency between the tip and PJ properties are complex; and theoretical aspect of this interaction will be exposed to justify the shape of our tip and optical fiber used in our demonstrations. Methods to achieve such a needed optical fiber tip will also be described. Finally the ability to generate PJ out of the shaped optical fiber will be experimentally demonstrated and the potential applications for material processing will be exposed.

  11. Retrieval of a detached transseptal sheath tip from a right pulmonary artery branch following catheter ablation.

    PubMed

    Schricker, Amir A; Feld, Gregory K; Tsimikas, Sotirios

    2015-11-15

    Transseptal introducer sheaths are being used with increasing frequency for left-sided arrhythmia ablations and structural heart disease interventions. Sheath tip detachment and embolization is an uncommon but known complication, and several sheaths have been recalled due to such complications. We report a unique case of a fractured transseptal sheath tip that embolized to a branch of the right pulmonary artery in a patient who had undergone ablation of a left-sided atypical atrial flutter. During final removal of one of the two long 8.5-French SL1 transseptal sheaths used routinely as part of the ablation, the radiopaque tip of the sheath fractured and first embolized to the right atrium and subsequently to a secondary right pulmonary artery branch. Using techniques derived from percutaneous interventional approaches, including a multipurpose catheter, coronary guidewire, and monorail angioplasty balloon, the sheath tip was successfully wired through its inner lumen, trapped from the inside with the balloon, and removed from the body via a large femoral vein sheath, without complications. The approach detailed in this case may guide future cases and circumvent urgent surgical intervention. © 2015 Wiley Periodicals, Inc.

  12. Workplace Education Guide, 1999.

    ERIC Educational Resources Information Center

    Massachusetts State Dept. of Education, Boston.

    These eight chapters share diverse experiences, lessons, and tips gleaned by the Massachusetts Workplace Literacy Consortium. "Workplace Needs Analysis (WNA)" (Harneen Chernow, Emily Singer, Jenny Lee Utech) focuses on the Worker Education Program's (WEP's) strategy, including tools, access, interviews and focus groups, presenting findings to the…

  13. A Facilities Manager's Guide to Green Building Design.

    ERIC Educational Resources Information Center

    Simpson, Walter

    2001-01-01

    Explains how the "green building" approach to educational facilities design creates healthy, naturally lit, attractive buildings with lower operating and life cycle costs. Tips on getting started on a green design and overcoming the barriers to the green design concept are discussed. (GR)

  14. The Mobility Decision. 1990 Wheelchair Guide.

    ERIC Educational Resources Information Center

    Henke, Cliff

    1990-01-01

    This article presents tips for parents shopping for wheelchairs for children with special mobility needs. Manual versus power chairs, dimensions, maneuverability, weight, transportability, durability, adaptability, maximum/minimum speeds, battery life (for power chairs), climbing angle, and other features are discussed. Factors to consider in…

  15. The influences of tip clearance on the performance of nozzle blades of radial turbines - Experiment and performance prediction at three nozzle angles

    NASA Astrophysics Data System (ADS)

    Hyun, Yong-Ik; Yamaguchi, Michiteru; Hayami, Hiroshi; Senoo, Yasutoshi

    1988-05-01

    In order to study the influence of tip clearance on the turning angle and pressure loss of turbine nozzles, experimental results were obtained for nozzle angles at which the throat area was 0.8 and 1.4 times the rated condition. Contour maps of the total pressure loss and of the spanwise distributions of the mean exit-flow angle have been obtained. Although the two-layer flow model of Senoo et al., (1987) is shown to accurately predict the effects of tip clearance, it underestimates the clearance effect for a lightly loaded condition.

  16. Rapid change of chromomeric and pairing patterns of polytene chromosome tips in D. melanogaster: migration of polytene-nonpolytene transition zone?

    PubMed

    Roberts, P A

    1979-07-01

    The high variability of chromomeric patterns in near-terminal regions of polytene chromosome arms has been explored in a number of races, strains and hybrids of Drosophila melanogaster. Traditional explanations for tip differences between strains (differential compaction of chromatin, somatic or germinal deletion) are examined and, in the light of the reported observations, rejected. The range of polytene tip variability and rates of change in wild races are greater than has been supposed: strains formerly considered to be terminally deleted appear to gain terminal bands; others, formerly considered normal, appear to have lost them. Strains with high cell-to-cell tip variability are also described. Cell-to-cell variations, as well as much of the observed rapid changes in tip appearance, are probably due to heritable differences in the location of an abrupt transition zone between polytene and nonpolytene chromatin. A quantitative relationship between the amount of certain subterminal bands present and the frequency of tip association of nonhomologous chromosomes is shown and its possible significance for chromosome is shown and its possible for chromosome pairing discussed.

  17. NGS2: a focal plane array upgrade for the GeMS multiple tip-tilt wavefront sensor

    NASA Astrophysics Data System (ADS)

    Rigaut, François; Price, Ian; d'Orgeville, Céline; Bennet, Francis; Herrald, Nick; Paulin, Nicolas; Uhlendorf, Kristina; Garrel, Vincent; Sivo, Gaetano; Montes, Vanessa; Trujillo, Chad

    2016-07-01

    NGS2 is an upgrade for the multi-natural guide star tip-tilt & plate scale wavefront sensor for GeMS (Gemini Multi-Conjugate Adaptive Optics system). It uses a single Nüvü HNü-512 Electron-Multiplied CCD array that spans the entire GeMS wavefront sensor focal plane. Multiple small regions-of-interest are used to enable frame rates up to 800Hz. This set up will improve the optical throughput with respect to the current wavefront sensor, as well as streamline acquisition and allow for distortion compensation.

  18. Dark tip-tilt sensing

    NASA Astrophysics Data System (ADS)

    Arcidiacono, Carmelo; Ragazzoni, Roberto; Viotto, Valentina; Bergomi, Maria; Farinato, Jacopo; Magrin, Demetrio; Dima, Marco; Gullieuszik, Marco; Marafatto, Luca

    2016-07-01

    Dark wavefront sensing in its simplest and more crude form is a quad-cell with a round spot of dark ink acting as occulting disk at the center. This sensor exhibits fainter limiting magnitude than a conventional quad-cell, providing that the size of the occulting disk is slightly smaller than the size of the spot and smaller than the residual jitter movement in closed loop. We present simulations focusing a generic Adaptive Optics system using Natural Guide Stars to provide the tip-tilt signal. We consider a jitter spectrum of the residual correction including amplitudes exceeding the dark disk size.

  19. Truly hybrid interventional MR/X-ray system: investigation of in vivo applications.

    PubMed

    Fahrig, R; Butts, K; Wen, Z; Saunders, R; Kee, S T; Sze, D Y; Daniel, B L; Laerum, F; Pelc, N J

    2001-12-01

    The purpose of this study was to provide in vivo demonstrations of the functionality of a truly hybrid interventional x-ray/magnetic resonance (MR) system. A digital flat-panel x-ray system (1,024(2) array of 200 microm pixels, 30 frames per second) was integrated into an interventional 0.5-T magnet. The hybrid system is capable of MR and x-ray imaging of the same field of view without patient movement. Two intravascular procedures were performed in a 22-kg porcine model: placement of a transjugular intrahepatic portosystemic shunt (TIPS) (x-ray-guided catheterization of the hepatic vein, MR fluoroscopy-guided portal puncture, and x-ray-guided stent placement) and mock chemoembolization (x-ray-guided subselective catheterization of a renal artery branch and MR evaluation of perfused volume). The resolution and frame rate of the x-ray fluoroscopy images were sufficient to visualize and place devices, including nitinol guidewires (0.016-0.035-inch diameter) and stents and a 2.3-F catheter. Fifth-order branches of the renal artery could be seen. The quality of both real-time (3.5 frames per second) and standard MR images was not affected by the x-ray system. During MR-guided TIPS placement, the trocar and the portal vein could be easily visualized, allowing successful puncture from hepatic to portal vein. Switching back and forth between x-ray and MR imaging modalities without requiring movement of the patient was demonstrated. The integrated nature of the system could be especially beneficial when x-ray and MR image guidance are used iteratively.

  20. Effect of light dispersion of LED curing lights on resin composite polymerization.

    PubMed

    Vandewalle, Kraig S; Roberts, Howard W; Andrus, Jeffrey L; Dunn, William J

    2005-01-01

    This study evaluated the effect of light dispersion of halogen and LED curing lights on resin composite polymerization. One halogen (Optilux 501, SDS/Kerr, Orange, CA, USA) and five light-emitting diode (LED) curing lights (SmartLite iQ, Dentsply Caulk, Milford, DE, USA; LEDemetron 1, SDS/Kerr; FLASHlite 1001, Discus Dental, Culver City, CA, USA; UltraLume LED 5, Ultradent Products, South Jordan, UT, USA; Allegro, Den-Mat, Santa Maria, CA, USA) were used in this study. Specimens (8 mm diameter by 2 mm thick) were made in polytetrafluoroethylene molds using hybrid (Z100, 3M ESPE, St. Paul, MN, USA) and microfill (A110, 3M ESPE) composite resins. The top surface was polymerized for 5 seconds with the curing light guide tip positioned at a distance of 1 and 5 mm. Degree of conversion (DC) of the composite specimens was analyzed on the bottom surface using micro-Fourier Transform Infrared (FTIR) spectroscopy (Perkin-Elmer FTIR Spectrometer, Wellesley, PA, USA) 10 minutes after light activation. DC at the bottom of the 2 mm specimen was expressed as a percentage of the mean maximum DC. Five specimens were created per curing light and composite type (n=5). Percent mean DC ratios and SDs were calculated for each light under each testing condition. Data were analyzed by analysis of variance (ANOVA)/Tukey's test (alpha = .05). A beam analyzer (LBA-700, Spiricon, Logan, UT, USA) was used to record the emitted light from the curing lights at 0 and 5 mm distances (n=5). A Top Hat factor was used to compare the quality of the emitted beam profile (LBA/PC, Spiricon). The divergence angle from vertical was also determined in the x- and y-axes (LBA/PC). Mean values and SDs were calculated for each light under each testing condition (0 and 5 mm, x- and y-axes) and analyzed by a two-way ANOVA/Tukey's test (alpha = .05). For DC ratios, significant differences were found based on curing light and curing distance (p < .05). At 1 mm, Optilux 501 and FLASHlite 1001 produced significantly higher DC ratios with the hybrid resin composite. No differences were found among lights with the microfill at 1 mm. At 5 mm, SmartLite iQ, FLASHlite 1001, LEDemetron 1, and UltraLume LED 5 produced significantly higher DC ratios with the hybrid resin composite, whereas LEDemetron 1 and SmartLite iQ produced significantly higher DC ratios with the microfill resin composite. The UltraLume LED 5, Allegro, and Optilux 501 had significant reductions in mean DC ratios at curing distances of 1 and 5 mm with both resin composite types. For dispersion of light, significant differences were found in Top Hat factor and divergence angle (p < .001). SmartLite iQ had overall the highest Top Hat factor and lowest divergence angle of tested lights. A linear regression analysis relating pooled DC with pooled Top Hat factors and divergence angles found a very good correlation (r2 = .86) between dispersion of light over distance and the ability to polymerize resin composite. The latest generation of LED curing lights provides DC ratios similar to or better than the halogen curing light at a curing distance of 5 mm. Dispersion of light plays a significant role in the DC of resin composite. To maximize curing effectiveness, light guides should be maintained in close proximity to the surface of the light-activated restorative material.

  1. UKIRT fast guide system improvements

    NASA Astrophysics Data System (ADS)

    Balius, Al; Rees, Nicholas P.

    1997-09-01

    The United Kingdom Infra-Red Telescope (UKIRT) has recently undergone the first major upgrade program since its construction. One part of the upgrade program was an adaptive tip-tilt secondary mirror closed with a CCD system collectively called the fast guide system. The installation of the new secondary and associated systems was carried out in the first half of 1996. Initial testing of the fast guide system has shown great improvement in guide accuracy. The initial installation included a fixed integration time CCD. In the first part of 1997 an integration time controller based on computed guide star luminosity was implemented in the fast guide system. Also, a Kalman type estimator was installed in the image tracking loop based on a dynamic model and knowledge of the statistical properties of the guide star position error measurement as a function of computed guide star magnitude and CCD integration time. The new configuration was tested in terms of improved guide performance nd graceful degradation when tracking faint guide stars. This paper describes the modified fast guide system configuration and reports the results of performance tests.

  2. Sky coverage modeling for the whole sky for laser guide star multiconjugate adaptive optics.

    PubMed

    Wang, Lianqi; Andersen, David; Ellerbroek, Brent

    2012-06-01

    The scientific productivity of laser guide star adaptive optics systems strongly depends on the sky coverage, which describes the probability of finding natural guide stars for the tip/tilt wavefront sensor(s) to achieve a certain performance. Knowledge of the sky coverage is also important for astronomers planning their observations. In this paper, we present an efficient method to compute the sky coverage for the laser guide star multiconjugate adaptive optics system, the Narrow Field Infrared Adaptive Optics System (NFIRAOS), being designed for the Thirty Meter Telescope project. We show that NFIRAOS can achieve more than 70% sky coverage over most of the accessible sky with the requirement of 191 nm total rms wavefront.

  3. The RIF Guide to Encouraging Young Readers. A Fun-filled Sourcebook of over 200 Favorite Reading Activities of Kids and Parents from Across the Country, Plus an Annotated List of Books and Resources.

    ERIC Educational Resources Information Center

    Graves, Ruth, Ed.

    Based on the notion that reading is both fun and fundamental, this book contains a stimulating array of activities that parents can use to engage their children in reading from the toddler stage through primary school. The first section provides information on how to use the guide, and some tips for encouraging young readers. The second and major…

  4. Technique tip: use of anterior cruciate ligament jig for hindfoot fusion by calcanio-talo-tibial nail.

    PubMed

    Haque, Syed; Sarkar, Jay

    2012-08-01

    The use of intramedullary nail fixation for tibio-talo-calcaneal fusion is gaining popularity. There is chance of failure of procedure following faulty operative technique specially alignment. The article describes a useful application of tibial tunnel jig in inserting the calcanio-talo-tibial guide wire. There is precision of few millimeters in the exit point of guide wire on talus. The authors believe that this helps in better positioning of nail and hence better alignment and better operative outcome.

  5. Safety Tips from the Expert Witness.

    ERIC Educational Resources Information Center

    Gray, Gary R.

    1995-01-01

    Many physical educators and coaches use the potential for liability to guide their decisions about conducting activities. By understanding expert witnesses' roles in negligence actions, surer planning, teaching, and coaching are possible. The paper describes issues that expert witnesses examine in negligence actions against physical educators,…

  6. Selecting a Weight-Loss Program

    MedlinePlus

    ... 3700, April 2008. Healthy Weight Tip Choose weight-loss programs that encourage healthy behaviors that help you lose weight gradually and maintain your weight over time. Looking for easy-to-use information for eating healthy on the go? The Maintaining a Healthy Weight On the Go pocket guide ...

  7. Operations and Maintenance January Newsletter | Poster

    Cancer.gov

    One of the many services provided through our Exterior and Structural Systems shop is “Moving” Services. Planning, coordination, and proper paperwork are critical to ensure a successful move. Please read on for some tips and factoids to help guide you through your requests for these services.

  8. Guide to transcribing and summarizing oral histories : Historic Columbia River Highway oral history project.

    DOT National Transportation Integrated Search

    2010-03-01

    Because how we speak can be very different from how we write, transcribing interviews is often more complicated than copying a persons words down verbatim. Thus, this document includes tips for transcribing oral history interviews and provides gui...

  9. Tips for Implementing a Wireless Network

    ERIC Educational Resources Information Center

    Walery, Darrell

    2005-01-01

    This article provides a quick start guide to provide educators with the basic points to consider before installing a wireless network in the school. Since many school districts have already implemented wireless networks, there is a lot of information available online to assist in the process.

  10. Teaching Tips: Mind Magnets

    ERIC Educational Resources Information Center

    Fortenberry, Callie L.; Fowler, Teri W.

    2006-01-01

    Mind magnets are maps to guide instruction and facilitate the comprehension processes. They extend individual comprehension strategy instruction, which does not typically show students how to link application of appropriate strategies to whole texts. The mind magnet framework allows teachers to plan powerful interactions between the reader and the…

  11. Fiber-optic Singlet Oxygen [1O2 (1Δg)] Generator Device Serving as a Point Selective Sterilizer

    PubMed Central

    Aebisher, David; Zamadar, Matibur; Mahendran, Adaickapillai; Ghosh, Goutam; McEntee, Catherine; Greer, Alexander

    2016-01-01

    Traditionally, Type II heterogeneous photo-oxidations produce singlet oxygen via external irradiation of a sensitizer and external supply of ground-state oxygen. A potential improvement is reported here. A hollow-core fiber-optic device was developed with an “internal” supply of light and flowing oxygen, and a porous photosensitizer-end capped configuration. Singlet oxygen was delivered through the fiber tip. The singlet oxygen steady-state concentration in the immediate vicinity of the probe tip was ca 20 fM by N-benzoyl-DL-methionine trapping. The device is portable and the singlet oxygen-generating tip is maneuverable, which opened the door to simple disinfectant studies. Complete Escherichia coli inactivation was observed in 2 h when the singlet oxygen sensitizing probe tip was immersed in 0.1 mL aqueous samples of 0.1–4.4 × 107 cells. Photobleaching of the probe tip occurred after ca 12 h of use, requiring baking and sensitizer reloading steps for reuse. PMID:20497367

  12. Anisotropic excitation of surface plasmon polaritons on a metal film by a scattering-type scanning near-field microscope with a non-rotationally-symmetric probe tip

    NASA Astrophysics Data System (ADS)

    Walla, Frederik; Wiecha, Matthias M.; Mecklenbeck, Nicolas; Beldi, Sabri; Keilmann, Fritz; Thomson, Mark D.; Roskos, Hartmut G.

    2018-01-01

    We investigated the excitation of surface plasmon polaritons on gold films with the metallized probe tip of a scattering-type scanning near-field optical microscope (s-SNOM). The emission of the polaritons from the tip, illuminated by near-infrared laser radiation, was found to be anisotropic and not circularly symmetric as expected on the basis of literature data. We furthermore identified an additional excitation channel via light that was reflected off the tip and excited the plasmon polaritons at the edge of the metal film. Our results, while obtained for a non-rotationally-symmetric type of probe tip and thus specific for this situation, indicate that when an s-SNOM is employed for the investigation of plasmonic structures, the unintentional excitation of surface waves and anisotropic surface wave propagation must be considered in order to correctly interpret the signatures of plasmon polariton generation and propagation.

  13. Ecophysiological function of leaf 'windows' in Lithops species - 'Living Stones' that grow underground.

    PubMed

    Martin, C E; Brandmeyer, E A; Ross, R D

    2013-01-01

    Leaf temperatures were lower when light entry at the leaf tip window was prevented through covering the window with reflective tape, relative to leaf temperatures of plants with leaf tip windows covered with transparent tape. This was true when leaf temperatures were measured with an infrared thermometer, but not with a fine-wire thermocouple. Leaf tip windows of Lithops growing in high-rainfall regions of southern Africa were larger than the windows of plants (numerous individuals of 17 species) growing in areas with less rainfall and, thus, more annual insolation. The results of this study indicate that leaf tip windows of desert plants with an underground growth habit can allow entry of supra-optimal levels of radiant energy, thus most likely inhibiting photosynthetic activity. Consequently, the size of the leaf tip windows correlates inversely with habitat solar irradiance, minimising the probability of photoinhibition, while maximising the absorption of irradiance in cloudy, high-rainfall regions. © 2012 German Botanical Society and The Royal Botanical Society of the Netherlands.

  14. Using a sharp metal tip to control the polarization and direction of emission from a quantum dot.

    PubMed

    Ghimire, Anil; Shafran, Eyal; Gerton, Jordan M

    2014-09-24

    Optical antennas can be used to manipulate the direction and polarization of radiation from an emitter. Usually, these metallic nanostructures utilize localized plasmon resonances to generate highly directional and strongly polarized emission, which is determined predominantly by the antenna geometry alone, and is thus not easily tuned. Here we show experimentally that the emission polarization can be manipulated using a simple, nonresonant scanning probe consisting of the sharp metallic tip of an atomic force microscope; finite element simulations reveal that the emission simultaneously becomes highly directional. Together, the measurements and simulations demonstrate that interference between light emitted directly into the far field with that elastically scattered from the tip apex in the near field is responsible for this control over polarization and directionality. Due to the relatively weak emitter-tip coupling, the tip must be positioned very precisely near the emitter, but this weak coupling also leads to highly tunable emission properties with a similar degree of polarization and directionality compared to resonant antennas.

  15. Common-path low-coherence interferometry fiber-optic sensor guided microincision

    NASA Astrophysics Data System (ADS)

    Zhang, Kang; Kang, Jin U.

    2011-09-01

    We propose and demonstrate a common-path low-coherence interferometry (CP-LCI) fiber-optic sensor guided precise microincision. The method tracks the target surface and compensates the tool-to-surface relative motion with better than +/-5 μm resolution using a precision micromotor connected to the tool tip. A single-fiber distance probe integrated microdissector was used to perform an accurate 100 μm incision into the surface of an Intralipid phantom. The CP-LCI guided incision quality in terms of depth was evaluated afterwards using three-dimensional Fourier-domain optical coherence tomography imaging, which showed significant improvement of incision accuracy compared to free-hand-only operations.

  16. Fan Noise Source Diagnostic Test Computation of Rotor Wake Turbulence Noise

    NASA Technical Reports Server (NTRS)

    Nallasamy, M.; Envia, E.; Thorp, S. A.; Shabbir, A.

    2002-01-01

    An important source mechanism of fan broadband noise is the interaction of rotor wake turbulence with the fan outlet guide vanes. A broadband noise model that utilizes computed rotor flow turbulence from a RANS code is used to predict fan broadband noise spectra. The noise model is employed to examine the broadband noise characteristics of the 22-inch Source Diagnostic Test fan rig for which broadband noise data were obtained in wind tunnel tests at the NASA Glenn Research Center. A 9-case matrix of three outlet guide vane configurations at three representative fan tip speeds are considered. For all cases inlet and exhaust acoustic power spectra are computed and compared with the measured spectra where possible. In general, the acoustic power levels and shape of the predicted spectra are in good agreement with the measured data. The predicted spectra show the experimentally observed trends with fan tip speed, vane count, and vane sweep. The results also demonstrate the validity of using CFD-based turbulence information for fan broadband noise calculations.

  17. The vibration compensation system for ARGOS

    NASA Astrophysics Data System (ADS)

    Peter, D.; Gaessler, W.; Borelli, J.; Kulas, M.

    2011-09-01

    For every adaptive optics system telescope vibrations can strongly reduce the performance. This is true for the receiver part of the system i.e. the telescope and wave front sensor part as well as for the transmitter part in the case of a laser guide star system. Especially observations in deep fields observed with a laser guide star system without any tip-tilt star will be greatly spoiled by telescope vibrations. The ARGOS GLAO system actually being built for the LBT aims to implement this kind of mode where wave front correction will rely purely on signals from the laser beacons. To remove the vibrations from the uplink path a vibration compensation system will be installed. This system uses accelerometers to measure the vibrations and corrects their effect with a small fast tip-tilt mirror. The controller of the system is built based on the assumption that the vibrations take place at a few distinct frequencies. Here I present a lab set-up of this system and show first results of the performance.

  18. Electromagnetic articulography treatment for an adult with Broca's aphasia and apraxia of speech.

    PubMed

    Katz, W F; Bharadwaj, S V; Carstens, B

    1999-12-01

    Electromagnetic articulography (EMA) was explored as a means of remediating [s]/[symbol in text] articulation deficits in the speech of an adult with Broca's aphasia and apraxia of speech. Over a 1-month period, the subject was provided with 2 different treatments in a counterbalanced procedure: (1) visually guided biofeedback concerning tongue-tip position and (2) a foil treatment in which a computer program delivered voicing-contrast stimuli for simple repetition. Kinematic and perceptual data suggest improvement resulting from visually guided biofeedback, both for nonspeech oral and, to a lesser extent, speech motor tasks. In contrast, the phonetic contrast treated in the foil condition showed only marginal improvement during the therapy session, with performance dropping back to baseline 10 weeks post-treatment. Although preliminary, the findings suggest that visual biofeedback concerning tongue-tip position can be used to treat nonspeech oral and (to a lesser extent) speech motor behavior in adults with Broca's aphasia and apraxia of speech.

  19. Root tips moving through soil

    PubMed Central

    Curlango-Rivera, Gilberto

    2011-01-01

    Root elongation occurs by the generation of new cells from meristematic tissue within the apical 1–2 mm region of root tips. Therefore penetration of the soil environment is carried out by newly synthesized plant tissue, whose cells are inherently vulnerable to invasion by pathogens. This conundrum, on its face, would seem to reflect an intolerable risk to the successful establishment of root systems needed for plant life. Yet root tip regions housing the meristematic tissues repeatedly have been found to be free of microbial infection and colonization. Even when spore germination, chemotaxis, and/or growth of pathogens are stimulated by signals from the root tip, the underlying root tissue can escape invasion. Recent insights into the functions of root border cells, and the regulation of their production by transient exposure to external signals, may shed light on long-standing observations. PMID:21455030

  20. Photoacoustic-guided convergence of light through optically diffusive media.

    PubMed

    Kong, Fanting; Silverman, Ronald H; Liu, Liping; Chitnis, Parag V; Lee, Kotik K; Chen, Y C

    2011-06-01

    We demonstrate that laser beams can be converged toward a light-absorbing target through optically diffusive media by using photoacoustic-guided interferometric focusing. The convergence of light is achieved by shaping the wavefront of the incident light with a deformable mirror to maximize the photoacoustic signal, which is proportional to the scattered light intensity at the light absorber. © 2011 Optical Society of America

  1. An ultrasound needle insertion guide in a porcine phantom model.

    PubMed

    Whittaker, S; Lethbridge, G; Kim, C; Keon Cohen, Z; Ng, I

    2013-08-01

    We compared nerve blockade with and without the Infiniti(TM) needle guide in an ultrasound in-plane porcine simulation. We recruited 30 anaesthetists with varying blockade experience. Using the guide, the needle tip was more visible (for a median (IQR [range]) of 67 (56-100]) % of the time; and invisible for 2 (1-4 [0-19]) s) than when the guide was not used (respectively 23 (13-43 [0-80]) % and 25 (9-52 [1-198]) s; both p < 0.001). The corresponding block times were 8 (6-10 [3-28]) s and 32 (15-67 [5-225]) s, respectively; p < 0.001. The needle guide reduced the block time and the time that the needle was invisible, irrespective of anaesthetist experience. Anaesthesia © 2013 The Association of Anaesthetists of Great Britain and Ireland.

  2. Mesoscopic effect of spectral modulation for the light transmitted by a SNOM tip

    NASA Astrophysics Data System (ADS)

    Rähn, M.; Pärs, M.; Palm, V.; Jaaniso, R.; Hizhnyakov, V.

    2010-06-01

    The effect of a tapered metal-coated optical fiber terminated by a sub-wavelength aperture (SWA) on the spectrum of the transmitted light is investigated experimentally. Under certain conditions a remarkable spectral modulation of the transmitted light can be observed. This effect is of a mesoscopic origin, occurring only for a certain interval of SWA diameters. One can conclude that a noticeable modulation appears when the number of the transmitted fiber modes is small but exceeds unity, thus indicating the presence of a phase shift between different modes. To discern between two possible sources of such phase shift, the fiber length dependence of the output spectrum has been studied. According to the results obtained for the used sample of 200 nm SNOM tip, the observed phase shift is mostly caused rather by the inherent modal dispersion of the multimode fiber than by the mode-dependent light slowdown in the tapered region close to SWA due to the coupling to surface plasmons of the metal coating. The SWA acts here mainly as an effective mode filter.

  3. Real-Time MRI-Guided Cardiac Cryo-Ablation: A Feasibility Study.

    PubMed

    Kholmovski, Eugene G; Coulombe, Nicolas; Silvernagel, Joshua; Angel, Nathan; Parker, Dennis; Macleod, Rob; Marrouche, Nassir; Ranjan, Ravi

    2016-05-01

    MRI-based ablation provides an attractive capability of seeing ablation-related tissue changes in real time. Here we describe a real-time MRI-based cardiac cryo-ablation system. Studies were performed in canine model (n = 4) using MR-compatible cryo-ablation devices built for animal use: focal cryo-catheter with 8 mm tip and 28 mm diameter cryo-balloon. The main steps of MRI-guided cardiac cryo-ablation procedure (real-time navigation, confirmation of tip-tissue contact, confirmation of vessel occlusion, real-time monitoring of a freeze zone formation, and intra-procedural assessment of lesions) were validated in a 3 Tesla clinical MRI scanner. The MRI compatible cryo-devices were advanced to the right atrium (RA) and right ventricle (RV) and their position was confirmed by real-time MRI. Specifically, contact between catheter tip and myocardium and occlusion of superior vena cava (SVC) by the balloon was visually validated. Focal cryo-lesions were created in the RV septum. Circumferential ablation of SVC-RA junction with no gaps was achieved using the cryo-balloon. Real-time visualization of freeze zone formation was achieved in all studies when lesions were successfully created. The ablations and presence of collateral damage were confirmed by T1-weighted and late gadolinium enhancement MRI and gross pathological examination. This study confirms the feasibility of a MRI-based cryo-ablation system in performing cardiac ablation procedures. The system allows real-time catheter navigation, confirmation of catheter tip-tissue contact, validation of vessel occlusion by cryo-balloon, real-time monitoring of a freeze zone formation, and intra-procedural assessment of ablations including collateral damage. © 2016 Wiley Periodicals, Inc.

  4. Gadolinium Use in Spine Pain Management Procedures for Patients with Contrast Allergies: Results in 527 Procedures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Safriel, Yair; Ang, Roberto; Ali, Muhammed

    2008-03-15

    Introduction. To review the safety and efficacy of gadolinium in spine pain management procedures in patients at high risk for a contrast reaction and who are not suitable candidates for the use of standard non-ionic contrast. Methods. We reviewed records over a 61-month period of all image-guided spinal pain management procedures where patients had allergies making them unsuitable candidates for standard non-ionic contrast and where gadolinium was used to confirm needle tip placement prior to injection of medication. Results. Three hundred and four outpatients underwent 527 procedures. A spinal needle was used in all but 41 procedures. Gadolinium was visualizedmore » using portable C-arm fluoroscopy in vivo allowing for confirmation of needle tip location. The gadolinium dose ranged from 0.2 to 10 ml per level. The highest dose received by one patient was 15.83 ml intradiscally during a three-level discogram. Three hundred and one patients were discharged without complication or known delayed complications. One patient had documented intrathecal injection but without sequelae and 2 patients who underwent cervical procedures experienced seizures requiring admission to the intensive care unit. Both the latter patients were discharged without any further complications. Conclusion. Based on our experience we recommend using gadolinium judiciously for needle tip confirmation. We feel more confident using gadolinium in the lumbar spine and in cervical nerve blocks. Gadolinium should probably not be used as an injectate volume expander. The indications for gadolinium use in cervical needle-guided spine procedures are less clear and use of a blunt-tipped needle should be considered.« less

  5. A comparison of needle tip localization accuracy using 2D and 3D trans-rectal ultrasound for high-dose-rate prostate cancer brachytherapy treatment planning

    NASA Astrophysics Data System (ADS)

    Hrinivich, W. Thomas; Hoover, Douglas A.; Surry, Kathleen; Edirisinghe, Chandima; Montreuil, Jacques; D'Souza, David; Fenster, Aaron; Wong, Eugene

    2016-03-01

    Background: High-dose-rate brachytherapy (HDR-BT) is a prostate cancer treatment option involving the insertion of hollow needles into the gland through the perineum to deliver a radioactive source. Conventional needle imaging involves indexing a trans-rectal ultrasound (TRUS) probe in the superior/inferior (S/I) direction, using the axial transducer to produce an image set for organ segmentation. These images have limited resolution in the needle insertion direction (S/I), so the sagittal transducer is used to identify needle tips, requiring a manual registration with the axial view. This registration introduces a source of uncertainty in the final segmentations and subsequent treatment plan. Our lab has developed a device enabling 3D-TRUS guided insertions with high S/I spatial resolution, eliminating the need to align axial and sagittal views. Purpose: To compare HDR-BT needle tip localization accuracy between 2D and 3D-TRUS. Methods: 5 prostate cancer patients underwent conventional 2D TRUS guided HDR-BT, during which 3D images were also acquired for post-operative registration and segmentation. Needle end-length measurements were taken, providing a gold standard for insertion depths. Results: 73 needles were analyzed from all 5 patients. Needle tip position differences between imaging techniques was found to be largest in the S/I direction with mean+/-SD of -2.5+/-4.0 mm. End-length measurements indicated that 3D TRUS provided statistically significantly lower mean+/-SD insertion depth error of -0.2+/-3.4 mm versus 2.3+/-3.7 mm with 2D guidance (p < .001). Conclusions: 3D TRUS may provide more accurate HDR-BT needle localization than conventional 2D TRUS guidance for the majority of HDR-BT needles.

  6. Holographic studies of shock waves within transonic fan rotors

    NASA Technical Reports Server (NTRS)

    Benser, W. A.; Bailey, E. E.; Gelder, T. F.

    1973-01-01

    Pulsed laser holographic interferometry has been applied to the detection of shock patterns in the outer span regions of high tip speed transonic rotors. The first holographic approach used ruby laser light reflected from a portion of the centerbody just ahead of the rotor. These holograms showed the bow wave patterns upstream of the rotor and the shock patterns just inside the blade row near the tip. Much of the region of interest was in the shadow of the blade leading edge and could not be visualized. The second holographic approach, on a different rotor, used light transmitted diagonally across the inlet annulus past the centerbody. This approach gave a more extensive view of the region bounded by the blade leading and trailing edges, by the part span shroud and by the blade tip. These holograms showed the passage shock emanating from the blade leading edge and a moderately strong conical shock originating at the intersection of the part span shroud leading edge and the blade suction surface. Reasonable details of the shock patterns were obtained from holograms which were made without extensive rig modifications.

  7. Initial Results of the SSPX Transient Internal Probe System for Measuring Toroidal Field Profiles

    NASA Astrophysics Data System (ADS)

    Holcomb, C. T.; Jarboe, T. R.; Mattick, A. T.; Hill, D. N.; McLean, H. S.; Wood, R. D.; Cellamare, V.

    2000-10-01

    Lawrence Livermore National Laboratory, Livermore, CA 94550, USA. The Sustained Spheromak Physics Experiment (SSPX) is using a field profile diagnostic called the Transient Internal Probe (TIP). TIP consists of a verdet-glass bullet that is used to measure the magnetic field by Faraday rotation. This probe is shot through the spheromak by a light gas gun at speeds near 2 km/s. An argon laser is aligned along the path of the probe. The light passes through the probe and is retro-reflected to an ellipsometer that measures the change in polarization angle. The measurement is spatially resolved down to the probes’ 1 cm length to within 15 Gauss. Initial testing results are given. This and future data will be used to determine the field profile for equilibrium reconstruction. TIP can also be used in conjunction with wall probes to map out toroidal mode amplitudes and phases internally. This work was performed under the auspices of US DOE by the University of California Lawrence Livermore National Laboratory under Contract No. W-7405-ENG-48.

  8. Guide for optimizing the effectiveness and the efficiency of roadway lighting.

    DOT National Transportation Integrated Search

    2012-06-01

    The objective of the present project was to develop a simple guide for roadway lighting replacement : approaches using new light source technologies to maintain visibility for safety, while reducing energy use. : Several roadway types were evaluated:...

  9. Optics: Light, Color, and Their Uses. An Educator's Guide with Activities in Science and Mathematics.

    ERIC Educational Resources Information Center

    National Aeronautics and Space Administration, Huntsville, AL. George C. Marshall Space Flight Center.

    This educator's guide from discusses optics, light, color and their uses. Activities include: (1) "Reflection of Light with a Plane (Flat) Mirror--Trace a Star"; (2) "Reflection of Light with Two Plane Mirrors--Double Mirrors Placed at a 90-Degree Angle"; (3) "Reflection of Light with Two Plane Mirrors--Double Mirrors Placed at a Number of…

  10. Design and evaluation of an intraocular B-scan OCT-guided 36-gauge needle

    NASA Astrophysics Data System (ADS)

    Shen, Jin H.; Joos, Karen M.

    2015-03-01

    Optical coherence tomography imaging is widely used in ophthalmology and optometry clinics for diagnosing retinal disorders. External microscope-mounted OCT operating room systems have imaged retinal changes immediately following surgical manipulations. However, the goal is to image critical surgical maneuvers in real time. External microscope-mounted OCT systems have some limitations with problems tracking constantly moving intraocular surgical instruments, and formation of absolute shadows by the metallic surgical instruments upon the underlying tissues of interest. An intraocular OCT-imaging probe was developed to resolve these problems. A disposable 25-gauge probe tip extended beyond the handpiece, with a 36-gauge needle welded to a disposable tip with its end extending an additional 3.5 mm. A sealed 0.35 mm diameter GRIN lens protected the fiber scanner and focused the scanning beam at a 3 to 4 mm distance. The OCT engine was a very high-resolution spectral-domain optical coherence tomography (SDOCT) system (870 nm, Bioptigen, Inc. Durham, NC) which produced 2000 A-scan lines per B-scan image at a frequency of 5 Hz with the fiber optic oscillations matched to this frequency. Real-time imaging of the needle tip as it touched infrared paper was performed. The B-scan OCT-needle was capable of real-time performance and imaging of the phantom material. In the future, the B-scan OCT-guided needle will be used to perform sub-retinal injections.

  11. A tip/tilt mirror with large dynamic range for the ESO VLT Four Laser Guide Star Facility

    NASA Astrophysics Data System (ADS)

    Rijnveld, N.; Henselmans, R.; Nijland, B.

    2011-09-01

    One of the critical elements in the Four Laser Guide Star Facility (4LGSF) for the ESO Very Large Telescope (VLT) is the Optical Tube Assembly (OTA), consisting of a stable 20x laser beam expander and an active tip/tilt mirror, the Field Selector Mechanism (FSM). This paper describes the design and performance testing of the FSM. The driving requirement for the FSM is its large stroke of +/-6.1 mrad, in combination with less than 1.5 μrad RMS absolute accuracy. The FSM design consists of a Zerodur mirror, bonded to a membrane spring and strut combination to allow only tip and tilt. Two spindle drives actuate the mirror, using a stiffness based transmission to increase resolution. Absolute accuracy is achieved with two differential inductive sensor pairs. A prototype of the FSM is realized to optimize the control configuration and measure its performance. Friction in the spindle drive is overcome by creating a local velocity control loop between the spindle drives and the shaft encoders. Accuracy is achieved by using a cascaded low bandwidth control loop with feedback from the inductive sensors. The pointing jitter and settling time of the FSM are measured with an autocollimator. The system performance meets the strict requirements, and is ready to be implemented in the first OTA.

  12. Reporting guide for laser-light shows and displays (21 CFR 1002)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    The guide is to be used for reporting laser-light shows or displays incorporating Class IIIb or Class IV lasers only. Separate reports are not required for shows or displays that incorporate Class I, IIa, II, or IIIa laser-projection systems. Such show descriptions must be included in the user instructions and the report for the laser projector. Laser projectors used in any light shows or displays regardless of the class of the projector must be certified by the manufacturer and reported using the guide titled, Guide for Preparing Initial Reports and Model Change Reports on Lasers and Products Containing Lasers, HHSmore » Publication FDA 86-8259. These guides assist manufacturers in providing the information that the Center for Devices and Radiological Health (CDRH) needs to determine how laser-light-shown projections and laser-light shows comply with the Federal standard for laser products (21 CDR 1040.10 and 1040.11) and with the conditions of an approved variance.« less

  13. The Portable Pediatrician.

    ERIC Educational Resources Information Center

    Markel, Howard; And Others

    This ready reference health guide features 240 major topics that occur regularly in clinical work with children and adolescents. It sorts out the information vital to successful management of common health problems and concerns by presentation of tables, charts, lists, criteria for diagnosis, and other useful tips. References on which the entries…

  14. The Physical Reality of Molecules: They're Dense and They Move Around!

    ERIC Educational Resources Information Center

    Silverstein, Todd P.

    1995-01-01

    Describes a simple and graphic demonstration of molecular motion that utilizes a hot plate, a beaker, tap water, India ink, and a Pasteur pipette with a rubber bulb. Provides tips on guiding students to an understanding of molecular motion using this demonstration. (DDR)

  15. Archery: A Planning Guide for Group and Individual Instruction.

    ERIC Educational Resources Information Center

    American Association for Health, Physical Education, and Recreation, Washington, DC.

    This instructor's manual for group or individual instruction in archery includes line drawings as illustrations. The manual advances from facilities to beginning instruction and general instructional practices (safety tips, instructional aids, archery etiquette) to intermediate instruction (discussions of causes of faulty arrow flight, analysis of…

  16. Living in Japan. Intercultural Exchange Series. Revised.

    ERIC Educational Resources Information Center

    Hawkinson, Annie

    The guide provides a brief introduction to the culture and language of Japan, and is designed for visitors, students, and business travelers. It offers practical information on various aspects of daily living, including: money; banks; food; restaurants; hotels; tipping; postal and telecommunications services; transportation; shopping; health and…

  17. Buyer's Guide to Classroom Furniture.

    ERIC Educational Resources Information Center

    Neugebauer, Roger

    1996-01-01

    Provides advice to child care center directors on purchasing the center's furniture. Contains a series of questions that directors should ask related to purchasing furniture, based on advice from manufacturers and dealers. Summarizes the key factors needed to consider when purchasing classroom furniture and includes tips on buying from catalogs…

  18. Rotating coherent flow structures as a source for narrowband tip clearance noise from axial fans

    NASA Astrophysics Data System (ADS)

    Zhu, Tao; Lallier-Daniels, Dominic; Sanjosé, Marlène; Moreau, Stéphane; Carolus, Thomas

    2018-03-01

    Noise from axial fans typically increases significantly as the tip clearance is increased. In addition to the broadband tip clearance noise at the design flow rate, narrowband humps also associated with the tip flow are observed in the far-field acoustic spectra at lower flow rate. In this study, both experimental and numerical methods are used to shed more light on the noise generation mechanism of this narrowband tip clearance noise and provide a unified description of this source. Unsteady aeroacoustic predictions with the Lattice-Boltzmann Method (LBM) are successfully compared with experiment. Such a validation allows using LBM data to conduct a detailed modal analysis of the pressure field for detecting rotating coherent flow structures which might be considered as noise sources. As previously found in ring fans the narrowband humps in the far-field noise spectra are found to be related to the tip clearance noise that is generated by an interaction of coherent flow structures present in the tip region with the leading edge of the impeller blades. The visualization of the coherent structures shows that they are indeed part of the unsteady tip clearance vortex structures. They are hidden in a complex, spatially and temporally inhomogeneous flow field, but can be recovered by means of appropriate filtering techniques. Their pressure trace corresponds to the so-called rotational instability identified in previous turbomachinery studies, which brings a unified picture of this tip-noise phenomenon for the first time.

  19. Light sources and output couplers for a backlight with switchable emission angles

    NASA Astrophysics Data System (ADS)

    Fujieda, Ichiro; Imai, Keita; Takagi, Yoshihiko

    2007-09-01

    For switching viewing angles of a liquid crystal display, we proposed to place a liquid crystal device between an LED and a light-guide of a backlight. The first key component for this configuration is a light source with electronically-controlled emission angles. Here, we construct such a device by stacking an optical film and a polymer-network liquid crystal (PNLC) cell on top of a chip-type LED. The optical film contains opaque parallel plates that limit the LED output in a narrow angular range. The PNLC cell either transmits or scatters the light emerging from the optical film. Experiment using a 15μm-thick PNLC cell shows that the angular distribution becomes 2.3 times wider by turning off the PNLC cell. We place this light source at one end of a light-guide so that the angular distribution of the light propagating inside is controlled. The second key component is some types of micro-strucrures built on the light-guide to out-couple the propagating light. We first attached various optical films on a light-guide surface. Although the angular distribution of the extracted light was switched successfully, light was mostly emitted into an oblique direction, approximately 60° from the plane normal. Next, we used a half-cylinder in place of the optical films. The curved surface of the cylinder was attached to the light-guide with a small amount of matching oil, which constituted an optical window. We measured that the angular distribution of the extracted light decreased to 35° FWHM from 62° FWHM by turning on the PNLC cell.

  20. Thermal effects of endoscopy in a human temporal bone model: Implications for endoscopic ear surgery

    PubMed Central

    Kozin, Elliott D.; Lehmann, Ashton; Carter, Margaret; Hight, Ed; Cohen, Michael; Nakajima, Hideko Heidi; Lee, Daniel J.

    2015-01-01

    Objective Although the theoretical risk of elevated temperatures during endoscopic ear surgery has been reported previously, neither temperature change nor heat distribution associated with the endoscope has been quantified. In this study, we measure temperature changes during rigid middle ear endoscopy in a human temporal bone model and investigate whether suction can act as a significant cooling mechanism. Study Design Human temporal bone model of endoscopic middle ear surgery. Methods Fresh human temporal bones were maintained at body temperature (~36°C). Temperature fluctuations were measured as a function of 1) distance between the tip of a 3mm 0° Hopkins rod and round window membrane, and 2) intensity of the light source. Infrared imaging determined the thermal gradient. For suction, a #20 French was utilized. Results We found: 1) an endoscope maximally powered by a xenon or LED light source resulted in a rapid temperature elevation up to 46°C within 0.5–1mm from the tip of the endoscope within 30–124 seconds; 2) elevated temperatures occurred up to 8mm from the endoscope tip; and 3) temperature decreased rapidly within 20–88 seconds of turning off the light source or applying suction. Conclusion Our findings have direct implications for avoiding excessive temperature elevation in endoscopic ear surgery. We recommend: 1) using submaximal light intensity, 2) frequent repositioning of the endoscope, and 3) removing the endoscope to allow tissue cooling. Use of suction provides rapid cooling of the middle ear space and may be incorporated in the design of new instrumentation for prolonged dissection. PMID:24604692

  1. Limitations of the commonly used simplified laterally uniform optical fiber probe-tissue interface in Monte Carlo simulations of diffuse reflectance

    PubMed Central

    Naglič, Peter; Pernuš, Franjo; Likar, Boštjan; Bürmen, Miran

    2015-01-01

    Light propagation models often simplify the interface between the optical fiber probe tip and tissue to a laterally uniform boundary with mismatched refractive indices. Such simplification neglects the precise optical properties of the commonly used probe tip materials, e.g. stainless steel or black epoxy. In this paper, we investigate the limitations of the laterally uniform probe-tissue interface in Monte Carlo simulations of diffuse reflectance. In comparison to a realistic probe-tissue interface that accounts for the layout and properties of the probe tip materials, the simplified laterally uniform interface is shown to introduce significant errors into the simulated diffuse reflectance. PMID:26504647

  2. Far-infrared tangential interferometer/polarimeter design and installation for NSTX-U

    DOE PAGES

    Scott, E. R.; Barchfeld, R.; Riemenschneider, P.; ...

    2016-08-09

    Here, the Far-infrared Tangential Interferometer/Polarimeter (FIReTIP) system has been refurbished and is being reinstalled on the National Spherical Torus Experiment—Upgrade (NSTX-U) to supply real-time line-integrated core electron density measurements for use in the NSTX-U plasma control system (PCS) to facilitate real-time density feedback control of the NSTX-U plasma. Inclusion of a visible light heterodyne interferometer in the FIReTIP system allows for real-time vibration compensation due to movement of an internally mounted retroreflector and the FIReTIP front-end optics. Real-time signal correction is achieved through use of a National Instruments CompactRIO field-programmable gate array.

  3. A real-time 3D range image sensor based on a novel tip-tilt-piston micromirror and dual frequency phase shifting

    NASA Astrophysics Data System (ADS)

    Skotheim, Øystein; Schumann-Olsen, Henrik; Thorstensen, Jostein; Kim, Anna N.; Lacolle, Matthieu; Haugholt, Karl-Henrik; Bakke, Thor

    2015-03-01

    Structured light is a robust and accurate method for 3D range imaging in which one or more light patterns are projected onto the scene and observed with an off-axis camera. Commercial sensors typically utilize DMD- or LCD-based LED projectors, which produce good results but have a number of drawbacks, e.g. limited speed, limited depth of focus, large sensitivity to ambient light and somewhat low light efficiency. We present a 3D imaging system based on a laser light source and a novel tip-tilt-piston micro-mirror. Optical interference is utilized to create sinusoidal fringe patterns. The setup allows fast and easy control of both the frequency and the phase of the fringe patterns by altering the axes of the micro-mirror. For 3D reconstruction we have adapted a Dual Frequency Phase Shifting method which gives robust range measurements with sub-millimeter accuracy. The use of interference for generating sine patterns provides high light efficiency and good focusing properties. The use of a laser and a bandpass filter allows easy removal of ambient light. The fast response of the micro-mirror in combination with a high-speed camera and real-time processing on the GPU allows highly accurate 3D range image acquisition at video rates.

  4. The performance of the MROI fast tip-tilt correction system

    NASA Astrophysics Data System (ADS)

    Young, John; Buscher, David; Fisher, Martin; Haniff, Christopher; Rea, Alexander; Seneta, Eugene; Sun, Xiaowei; Wilson, Donald; Farris, Allen; Olivares, Andres

    2014-07-01

    The fast tip-tilt (FTT) correction system for the Magdalena Ridge Observatory Interferometer (MROI) is being developed by the University of Cambridge. The design incorporates an EMCCD camera protected by a thermal enclosure, optical mounts with passive thermal compensation, and control software running under Xenomai real-time Linux. The complete FTT system is now undergoing laboratory testing prior to being installed on the first MROI unit telescope in the fall of 2014. We are following a twin-track approach to testing the closed-loop performance: tracking tip-tilt perturbations introduced by an actuated flat mirror in the laboratory, and undertaking end-to-end simulations that incorporate realistic higher-order atmospheric perturbations. We report test results that demonstrate (a) the high stability of the entire opto-mechanical system, realized with a completely passive design; and (b) the fast tip-tilt correction performance and limiting sensitivity. Our preliminary results in both areas are close to those needed to realise the ambitious stability and sensitivity goals of the MROI which aims to match the performance of current natural guide star adaptive optics systems.

  5. Conventional multi-slice computed tomography (CT) and cone-beam CT (CBCT) for computer-aided implant placement. Part II: reliability of mucosa-supported stereolithographic guides.

    PubMed

    Arisan, Volkan; Karabuda, Zihni Cüneyt; Pişkin, Bülent; Özdemir, Tayfun

    2013-12-01

    Deviations of implants that were placed by conventional computed tomography (CT)- or cone beam CT (CBCT)-derived mucosa-supported stereolithographic (SLA) surgical guides were analyzed in this study. Eleven patients were randomly scanned by a multi-slice CT (CT group) or a CBCT scanner (CBCT group). A total of 108 implants were planned on the software and placed using SLA guides. A new CT or CBCT scan was obtained and merged with the planning data to identify the deviations between the planned and placed implants. Results were analyzed by Mann-Whitney U test and multiple regressions (p < .05). Mean angular and linear deviations in the CT group were 3.30° (SD 0.36), and 0.75 (SD 0.32) and 0.80 mm (SD 0.35) at the implant shoulder and tip, respectively. In the CBCT group, mean angular and linear deviations were 3.47° (SD 0.37), and 0.81 (SD 0.32) and 0.87 mm (SD 0.32) at the implant shoulder and tip, respectively. No statistically significant differences were detected between the CT and CBCT groups (p = .169 and p = .551, p = .113 for angular and linear deviations, respectively). Implant placement via CT- or CBCT-derived mucosa-supported SLA guides yielded similar deviation values. Results should be confirmed on alternative CBCT scanners. © 2012 Wiley Periodicals, Inc.

  6. Heuristic estimation of electromagnetically tracked catheter shape for image-guided vascular procedures

    NASA Astrophysics Data System (ADS)

    Mefleh, Fuad N.; Baker, G. Hamilton; Kwartowitz, David M.

    2014-03-01

    In our previous work we presented a novel image-guided surgery (IGS) system, Kit for Navigation by Image Focused Exploration (KNIFE).1,2 KNIFE has been demonstrated to be effective in guiding mock clinical procedures with the tip of an electromagnetically tracked catheter overlaid onto a pre-captured bi-plane fluoroscopic loop. Representation of the catheter in KNIFE differs greatly from what is captured by the fluoroscope, due to distortions and other properties of fluoroscopic images. When imaged by a fluoroscope, catheters can be visualized due to the inclusion of radiopaque materials (i.e. Bi, Ba, W) in the polymer blend.3 However, in KNIFE catheter location is determined using a single tracking seed located in the catheter tip that is represented as a single point overlaid on pre-captured fluoroscopic images. To bridge the gap in catheter representation between KNIFE and traditional methods we constructed a catheter with five tracking seeds positioned along the distal 70 mm of the catheter. We have currently investigated the use of four spline interpolation methods for estimation of true catheter shape and have assesed the error in their estimation of true catheter shape. In this work we present a method for the evaluation of interpolation algorithms with respect to catheter shape determination.

  7. Implantation of active fixation leads in coronary veins for left ventricular stimulation: report of five cases.

    PubMed

    Hansky, Bert; Vogt, Juergen; Gueldner, Holger; Schulte-Eistrup, Sebastian; Lamp, Barbara; Heintze, Johannes; Horstkotte, Dieter; Koerfer, Reiner

    2007-01-01

    Securing transvenous left ventricular (LV) pacing leads without an active fixation mechanism in proximal coronary vein (CV) segments is usually challenging and frequently impossible. We investigated how active fixation leads can be safely implanted in this location, how to avoid perforating the free wall of the CV, and how to recognize and respond to perforations. In five patients with no alternative to LV pacing from proximal CV segments, 4 Fr SelectSecure (Medtronic, Minneapolis, MN, USA) leads, which have a fixed helix, were implanted through a modified 6 Fr guide catheter with a pre-shaped tip (Launcher, Medtronic). Active fixation leads were successfully implanted in proximal CVs in five patients. There were no complications. Acute and chronic pacing thresholds were comparable to those of conventional CV leads. The pre-shaped guide catheter tip remains in close proximity to the myocardial aspect of the CV, directing the lead helix toward a safe implantation site. If only proximal CV pacing sites are available, 4 Fr SelectSecure leads can be safely implanted through a modified Launcher guide catheter, avoiding more invasive implantation techniques. Other than venous stenting or implantation of leads with retractable tines, SelectSecure leads are expected to remain extractable.

  8. CT-Guided Interventions Using a Free-Hand, Optical Tracking System: Initial Clinical Experience

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schubert, Tilman, E-mail: TSchubert@uhbs.ch; Jacob, Augustinus L.; Pansini, Michele

    2013-08-01

    PurposeThe present study was designed to evaluate the geometrical accuracy and clinical applicability of a new, free-hand, CT-guided, optical navigation system.MethodsFifteen procedures in 14 consecutive patients were retrospectively analyzed. The navigation system was applied for interventional procedures on small target lesions, in cases with long needle paths, narrow access windows, or when an out-of-plane access was expected. Mean lesion volume was 27.9 ml, and mean distance to target measured was 107.5 mm. Eleven of 15 needle trajectories were planned as out-of-plane approaches regarding the axial CT plane.ResultsNinety-one percent of the biopsies were diagnostic. All therapeutic interventions were technically successful. Targetingmore » precision was high with a mean distance of the needle tip from planned target of 1.98 mm. Mean intervention time was 1:12 h. A statistically significant correlation between angular needle deviation and intervention time (p = 0.007), respiratory movement of the target (p = 0.008), and body mass index (p = 0.02) was detected. None of the evaluated parameters correlated significantly with the distance from the needle tip to the planned target.ConclusionsThe application of a navigation system for complex CT-guided procedures provided safe and effective targeting within a reasonable intervention time in our series.« less

  9. Near-Field Enhanced Photochemistry of Single Molecules in a Scanning Tunneling Microscope Junction.

    PubMed

    Böckmann, Hannes; Gawinkowski, Sylwester; Waluk, Jacek; Raschke, Markus B; Wolf, Martin; Kumagai, Takashi

    2018-01-10

    Optical near-field excitation of metallic nanostructures can be used to enhance photochemical reactions. The enhancement under visible light illumination is of particular interest because it can facilitate the use of sunlight to promote photocatalytic chemical and energy conversion. However, few studies have yet addressed optical near-field induced chemistry, in particular at the single-molecule level. In this Letter, we report the near-field enhanced tautomerization of porphycene on a Cu(111) surface in a scanning tunneling microscope (STM) junction. The light-induced tautomerization is mediated by photogenerated carriers in the Cu substrate. It is revealed that the reaction cross section is significantly enhanced in the presence of a Au tip compared to the far-field induced process. The strong enhancement occurs in the red and near-infrared spectral range for Au tips, whereas a W tip shows a much weaker enhancement, suggesting that excitation of the localized plasmon resonance contributes to the process. Additionally, using the precise tip-surface distance control of the STM, the near-field enhanced tautomerization is examined in and out of the tunneling regime. Our results suggest that the enhancement is attributed to the increased carrier generation rate via decay of the excited near-field in the STM junction. Additionally, optically excited tunneling electrons also contribute to the process in the tunneling regime.

  10. Lightness, chroma, and hue distributions of a shade guide as measured by a spectroradiometer.

    PubMed

    Lee, Yong-Keun; Yu, Bin; Lim, Ho-Nam

    2010-09-01

    The color attributes of commercially available shade guides have been measured by spectrophotometers (SP), which are designed to measure flat surfaces. However, there is limited information on the color distribution of shade guides as measured by spectroradiometers (SR), which are capable of measuring the color of curved surfaces. The purpose of this study was to determine the distributions of lightness (CIE L*) and chroma (C*(ab)) step intervals between adjacent shade tabs of a shade guide based on the lightness, chroma, and hue attributes measured by an SR. Lightness, chroma, hue angle, and CIE a* and b* values of the shade tabs (n=26) from a shade guide (Vitapan 3D-Master) were measured by an SR under daylight conditions. The distributions of the ratios in lightness and chroma of each tab compared with the lowest lightness tab or the lowest chroma tab were determined. The values for each color parameter were analyzed by a 3-way ANOVA with the factors of lightness, chroma, and hue designations of the shade tabs (alpha=.05). The chroma and CIE a* and b* values were influenced by the lightness, chroma, and hue designations of the shade tabs (P<.001); however, the lightness and hue angle were influenced by the lightness and hue designations, but not by the chroma designation. Distributions for the CIE a* and b* values, in each lightness group, corresponded with the chroma designation. However, the intervals in the lightness and chroma scales between adjacent tabs were not uniform. The intervals in the color parameters between adjacent shade tabs were not uniform based on SR measurements. Therefore, a shade guide in which shade tabs are more equally spaced by the color attributes, based on the values as measured by an SR along with observers' responses with respect to the equality of the intervals, should be devised. Copyright © 2010 The Editorial Council of the Journal of Prosthetic Dentistry. Published by Mosby, Inc. All rights reserved.

  11. [Sheng's acupuncture manipulation at bone-nearby acupoints and the academic thoughts].

    PubMed

    Sheng, Ji-li; Jin, Xiao-qing

    2014-11-01

    Sheng's acupuncture manipulation at bone-nearby acupoints is a set of needling manipulation of the chief physician of TCM, SHENG Xie-sun, summarized through his over 50 years clinical experiences and on the basis of Internal Classic. Regarding this manipulation, on the premise of acupoint selection based on syndrome differentiation, the acupoints close to bone are possibly selected and punctured, with the needle tip toward bone edge, and followed by the technique to achieve reducing purpose. Clinically, the significant immediate analgesia can be achieved in pain disorders such as headache and toothache. Professor Sheng thought, corresponding to the location of needle insertion and needling depth, the tissue layers of needle tip passing through should be considered specially. The site of needle insertion should be changeable so as to ensure the needle tip reaching the bone. This manipulation for analgesia provides a certain guide for acupuncture study, especially for the mechanism study on acupuncture analgesia.

  12. Illuminating system and method for specialized and decorative lighting using liquid light guides

    DOEpatents

    Zorn, C.J.; Kross, B.J.; Majewski, S.; Wojcik, R.F.

    1998-08-25

    The present invention comprises an illumination system for specialized decorative lighting including a light source, a flexible plastic tube sheath for distributing the light to a remote location, a transparent liquid core filling the tube that has an index of refraction greater than that of the plastic tube and an arrangement where light coupled from the light source is caused to leak from the liquid light guide at desired locations for the purposes of specialized lighting, such as underwater illumination in swimming pools. 5 figs.

  13. Illuminating system and method for specialized and decorative lighting using liquid light guides

    DOEpatents

    Zorn, Carl J.; Kross, Brian J.; Majewski, Stanislaw; Wojcik, Randolph F.

    1998-01-01

    The present invention comprises an illumination system for specialized decorative lighting including a light source, a flexible plastic tube sheath for distributing the light to a remote location, a transparent liquid core filling the tube that has an index of refraction greater than that of the plastic tube and an arrangement where light coupled from the light source is caused to leak from the liquid light guide at desired locations for the purposes of specialized lighting, such as underwater illumination in swimming pools.

  14. Optical system and method for gas detection and monitoring

    NASA Technical Reports Server (NTRS)

    Polzin, Kurt A. (Inventor); Sinko, John Elihu (Inventor); Korman, Valentin (Inventor); Witherow, William K. (Inventor); Hendrickson, Adam Gail (Inventor)

    2011-01-01

    A free-space optical path of an optical interferometer is disposed in an environment of interest. A light beam is guided to the optical interferometer using a single-mode optical fiber. The light beam traverses the interferometer's optical path. The light beam guided to the optical path is combined with the light beam at the end of the optical path to define an output light. A temporal history of the output light is recorded.

  15. 4. VIEW OF EMPIRE, STONE CABIN AND TIP TOP MINES. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. VIEW OF EMPIRE, STONE CABIN AND TIP TOP MINES. EMPIRE TAILING PILE IS VISIBLE IN LOWER CENTER (SLOPE WITH ORE CHUTE IS HIDDEN BY TREES ABOVE TAILINGS), TIP TOP IS VISIBLE IN RIGHT THIRD AND SLIGHTLY UPHILL IN ELEVATION FROM UPPER EMPIRE TAILINGS,(TO LOCATE, FIND THE V-SHAPED SPOT OF SNOW JUST BELOW THE RIDGE LINE ON FAR RIGHT OF IMAGE. TIP TOP BUILDING IS VISIBLE IN THE LIGHT AREA BELOW AND SLIGHTLY LEFT OF V-SHAPED SNOW SPOT), AND STONE CABIN II IS ALSO VISIBLE, (TO LOCATE, USE A STRAIGHT EDGE AND ALIGN WITH EMPIRE TAILINGS. THIS WILL DIRECT ONE THROUGH THE EDGE OF STONE CABIN II, WHICH IS THE DARK SPOT JUST BELOW THE POINT WHERE THE RIDGE LINE TREES STOP). STONE CABIN I IS LOCATED IN GENERAL VICINITY OF THE LONE TREE ON FAR LEFT RIDGE LINE. ... - Florida Mountain Mining Sites, Silver City, Owyhee County, ID

  16. A compact CCD-monitored atomic force microscope with optical vision and improved performances.

    PubMed

    Mingyue, Liu; Haijun, Zhang; Dongxian, Zhang

    2013-09-01

    A novel CCD-monitored atomic force microscope (AFM) with optical vision and improved performances has been developed. Compact optical paths are specifically devised for both tip-sample microscopic monitoring and cantilever's deflection detecting with minimized volume and optimal light-amplifying ratio. The ingeniously designed AFM probe with such optical paths enables quick and safe tip-sample approaching, convenient and effective tip-sample positioning, and high quality image scanning. An image stitching method is also developed to build a wider-range AFM image under monitoring. Experiments show that this AFM system can offer real-time optical vision for tip-sample monitoring with wide visual field and/or high lateral optical resolution by simply switching the objective; meanwhile, it has the elegant performances of nanometer resolution, high stability, and high scan speed. Furthermore, it is capable of conducting wider-range image measurement while keeping nanometer resolution. Copyright © 2013 Wiley Periodicals, Inc.

  17. Fabrication of near-field optical apertures in aluminium by a highly selective corrosion process in the evanescent field.

    PubMed

    Haefliger, D; Stemmer, A

    2003-03-01

    A simple, one-step process to fabricate high-quality apertures for scanning near-field optical microscope probes based on aluminium-coated silicon nitride cantilevers is presented. A thin evanescent optical field at a glass-water interface was used to heat the aluminium at the tip apex due to light absorption. The heat induced a breakdown of the passivating oxide layer and local corrosion of the metal, which selectively exposed the front-most part of the probe tip from the aluminium. Apertures with a protruding silicon nitride tip up to 72 nm in height were fabricated. The height of the protrusion was controlled by the extent of the evanescent field, whereas the diameter depended on the geometry of the probe substrate. The corrosion process proved to be self-terminating, yielding highly reproducible tip heights. Near-field optical resolution in a transmission mode of 85 nm was demonstrated.

  18. [Research on electron density in DC needle-plate corona discharge at atmospheric pressure].

    PubMed

    Liu, Zhi-Qiang; Guo, Wei; Liu, Tao-Tao; Wu, Wen-Shuo; Liu, Shu-Min

    2013-11-01

    Using needle-plate discharge device, corona discharge experiment was done in the atmosphere. Through photo of spot size of light-emitting area, the relationship between the voltage and thickness of corona layer was discussed. When the distance between tip and plate is fixed, the thickness of corona layer increases with the increase in voltage; when the voltage is fixed, the thickness of corona layer decreases with the increase in the distance between tip and plate. As spectral intensity of N2 (C3pi(u)) (337.1 nm)reflects high energy electron density, it was measured with emission spectrometry. The results show that high energy electron density is the biggest near the needle tip and the relationship between high energy electron density and voltage is basically linear increasing. Fixing voltage, high energy electron density decreases with the increase in the distance between tip and plate. When the voltage and the distance between tip and plate are fixed, the high energy electron density increases with the decrease in the curvature radius of needle tip. These results are of great importance for the study of plasma parameters of corona discharge.

  19. Fourier domain preconditioned conjugate gradient algorithm for atmospheric tomography.

    PubMed

    Yang, Qiang; Vogel, Curtis R; Ellerbroek, Brent L

    2006-07-20

    By 'atmospheric tomography' we mean the estimation of a layered atmospheric turbulence profile from measurements of the pupil-plane phase (or phase gradients) corresponding to several different guide star directions. We introduce what we believe to be a new Fourier domain preconditioned conjugate gradient (FD-PCG) algorithm for atmospheric tomography, and we compare its performance against an existing multigrid preconditioned conjugate gradient (MG-PCG) approach. Numerical results indicate that on conventional serial computers, FD-PCG is as accurate and robust as MG-PCG, but it is from one to two orders of magnitude faster for atmospheric tomography on 30 m class telescopes. Simulations are carried out for both natural guide stars and for a combination of finite-altitude laser guide stars and natural guide stars to resolve tip-tilt uncertainty.

  20. Guide to Working with Deaf and Hard of Hearing Students

    ERIC Educational Resources Information Center

    PEPNet, 2009

    2009-01-01

    This handbook was created for professors, high school teachers and vocational teachers new to interacting with Deaf and Hard of Hearing students. Topics include a general understanding of deafness, classroom accommodations, and communication tips. Appendices include: (1) A Professor Shares His Experience; (2) A Vocational Rehabilitation Counselor…

  1. The Complete Step-by-Step Guide to Designing and Teaching Online Courses

    ERIC Educational Resources Information Center

    Thormann, Joan; Zimmerman, Isa Kaftal

    2012-01-01

    In this valuable resource, experts share deep knowledge including practical "how-to" and preventive trouble-shooting tips. Instructors will learn about course design and development, instructional methods for online teaching, and student engagement and community building techniques. The book contains successful teaching strategies, guidance for…

  2. Tax Tips for Forest Landowners for the 2007 Tax Year

    Treesearch

    Linda Wang; John L. Greene

    2007-01-01

    This guide is designed to assist owners of forest land with timber tax information. It is current as of October 1, 2007, and supercedes Management Bulletin R8-MB 128. It is strictly for educational purposes; consult your legal and tax professionals for advice on a specific tax situation.

  3. TIPS: Trends for Inclusive Pediatric Services.

    ERIC Educational Resources Information Center

    Connecticut Univ. Health Center, Farmington.

    This guide was developed as part of a project to provide practicing physicians with training to enhance their understanding of and involvement with early intervention and the special education system in Connecticut. The introductory section notes that best practices in both primary medical care and early intervention promote care that is family…

  4. Physical Education for Students with Special Needs. Curriculum Support Series.

    ERIC Educational Resources Information Center

    Mahon, Michael J.

    The guide is intended to assist Manitoba physical education teachers in the process of integrating students with disabilities into regular physical education classes. The manual provides an introduction to students with special needs, stresses the need to create an accepting environment, discusses various teaching tips, and highlights resources…

  5. PowerPoint Workshop for Teachers[TM].

    ERIC Educational Resources Information Center

    Caughlin, Janet

    This guide for teachers to the Microsoft PowerPoint multimedia presentation program begins with a section that introduces what PowerPoint is and why teachers should use it, Windows 95/98 basics, Macintosh basics, getting started, PowerPoint toolbars, and presentation tips. The next section discusses learning PowerPoint, including creating a…

  6. How the Brain Learns: A Classroom Teacher's Guide. Second Edition.

    ERIC Educational Resources Information Center

    Sousa, David A.

    This book presents information to help teachers turn research on brain function into practical classroom activities and lessons, offering: brain facts; information on how the brain processes information; tips on maximizing retention; an information processing model that reflects new terminology regarding the memory systems; new research on how the…

  7. Survival Guide for the First-Year Special Education Teacher. Revised Edition.

    ERIC Educational Resources Information Center

    Cohen, Mary Kemper; And Others

    This guidebook offers practical advice to support special education teachers in their first year of teaching. The first chapter, "Getting Ready To Teach," outlines preparations necessary before school begins, such as organizing the classroom and establishing planning and record-keeping strategies. "Tips for the Classroom" lists what teachers…

  8. Promoting Learning. NIACE Lifelines in Adult Learning.

    ERIC Educational Resources Information Center

    Malone, Kate

    This document is intended to help adult educators in the United Kingdom promote learning. The guide presents practical advice, case studies, and tips for undertaking and implementing effective promotional work. Sections 1 through 11 discuss the following topics: recognizing the increasing need for lifelong learning; the rationale for campaigns…

  9. Introducing Economics: A Critical Guide for Teaching

    ERIC Educational Resources Information Center

    Maier, Mark H.; Nelson, Julie A.

    2007-01-01

    Make economics resonate to high school students. This practical handbook will help economics and social studies teachers foster critical thinking by introducing students to the real-life dimensions of the major controversies in contemporary economics. Filled with useful teaching tips and user-friendly information on finding engaging materials and…

  10. 100 Library Lifesavers: A Survival Guide for School Library Media Specialists.

    ERIC Educational Resources Information Center

    Bacon, Pamela S.

    This book contains tips (author's suggestions), tools (ready-to-use lifesavers), and talk (quotes from practicing media specialists) for school librarians at all grade levels. A total of 100 lifesavers are included, covering areas such as inventory, motivation strategies, disciplinary approaches, library checkout, Internet searching, the traveling…

  11. Basic Media in Education.

    ERIC Educational Resources Information Center

    Harrell, John

    Intended as a guide to the use of different media for use in the classroom, this document demonstrates alternative approaches that may be taken to depicting and communicating images and concepts to others. Some basic tools and materials--including a ruler, matte knife, rubber cement, stapler, felt-tip pens, paint brushes, and lettering pens--are…

  12. A Guide to Educational Equity in Vocational Programs.

    ERIC Educational Resources Information Center

    Illinois State Office of Education, Springfield. Div. of Adult Vocational and Technical Education.

    Designed for vocational teachers and administrators, this compilation of materials from various resources provides information, tips, and guidelines for evaluating instructional materials for sex bias and stereotypes, gives suggestions on using biased materials in a non-biased way, and presents guidelines for sex-equity in the classroom. Following…

  13. Simulated Real-Life Experiences Using Classified Ads in the Classroom.

    ERIC Educational Resources Information Center

    Hechler, Ellen

    This guide contains activities to help teachers give middle school students experience in practical life skills. Techniques include role playing and using classified advertisements from newspapers. The five lessons include teacher tips on conducting the activities. Lessons contain objectives, materials needed, discussion, and suggested dialogue.…

  14. Kids Cook! Fabulous Food for the Whole Family.

    ERIC Educational Resources Information Center

    Williamson, Sarah; Williamson, Zachary

    This step-by-step guide for children provides a collection of over 150 recipes for breakfasts, lunches, salads, dinners, snacks, and desserts, with an emphasis on safety and creativity. The first chapter gives information concerning kitchen safety, utensils, term definitions, measuring equivalents, cleanup tips and other useful instructions. The…

  15. STEVE -- User Guide and Reference Manual

    NASA Astrophysics Data System (ADS)

    Fish, Adrian

    This document describes an extended version of the EVE editor that has been tailored to the general Starlink user's requirements. This extended editor is STarlink Eve or STEve, and this document (along with it's introductory companion SUN/125) describes this editor, and offers additional help, advice and tips on general EVE usage.

  16. Winter Secrets: An Instant Lesson Plan.

    ERIC Educational Resources Information Center

    Collyer, Cam

    1997-01-01

    Outdoor lesson plan aims to stimulate student interest in animals' adaptations to winter and the various signs and clues to animal behavior. Includes questions for class discussion, tips for guiding the hike, and instructions for two games that illustrate the predator-prey relationship. Notes curriculum connections to the East York (Ontario) Board…

  17. Your Guide to Smart Year-Round Fundraising.

    ERIC Educational Resources Information Center

    Gensheimer, Cynthia Francis

    1994-01-01

    Describes three seasonal fund-raising projects that can be linked with the curriculum and require only a few parent volunteers. The projects are profitable without requiring large amounts of effort. They include selling holiday cards, conducting read-a-thons, and participating in save-the-rainforest group sales. Tips for holding successful fund…

  18. Teen Summer Reading Program, 1999. Read around the World.

    ERIC Educational Resources Information Center

    Virginia State Library, Richmond.

    This guide for the 1999 Virginia teen summer reading program for public libraries, "Read around the World," includes the following chapters: (1) "Reading and Teens," including serving the underserved, tips for teens, and a recipe for choosing a book to read for fun; (2) "Programming and Teens," including "The Why…

  19. Mechanism of Prism-Coupled Scanning Tunneling Microscope Light Emission

    NASA Astrophysics Data System (ADS)

    Iida, Wataru; Ahamed, Jamal U.; Katano, Satoshi; Uehara, Yoichi

    2011-09-01

    We have investigated the mechanism of scanning tunneling microscope light emission (STM-LE) in a prism-coupled configuration using finite difference time domain analysis. In this configuration, the sample is a metallic thin film evaporated on the bottom surface of a hemispherical glass prism. STM light emitted into the prism (prism-side emission) through the metallic film is measured. Since both localized surface plasmons (LSP) and surface plasmon polaritons (SPP) contribute to prism-side emission, this emission is stronger than that in conventional STM-LE measured from the sample surface side, which is radiated by LSP alone. We show that the spatial resolution of prism-side emission is determined not by the propagation length of SPP, but by the lateral size of LSP, similarly to conventional (i.e., tip side) STM-LE. Thus, we conclude that, by using the prism-coupled configuration, the signal level of STM-LE improves without the loss of spatial resolution attained in tip side emission.

  20. Pump-probe STM light emission spectroscopy for detection of photo-induced semiconductor-metal phase transition of VO2

    NASA Astrophysics Data System (ADS)

    Sakai, Joe; Katano, Satoshi; Kuwahara, Masashi; Uehara, Yoichi

    2017-10-01

    We attempted to observe pump-probe scanning tunneling microscopy (STM)-light emission (LE) from a VO2 thin film grown on a rutile TiO2(0 0 1) substrate, with an Ag tip fixed over a semiconducting domain. Laser pulses from a Ti:sapphire laser (wavelength 920 nm pulse width less than 1.5 ps) irradiated the tip-sample gap as pump and probe light sources. With a photon energy of 2.7 eV, suggesting phase transition from semiconducting monoclinic (M) to metallic rutile (R) phases in relation to the electronic band structure, faint LE was observed roughly 30 ps after the irradiation of the pump pulse, followed by retention for roughly 20 ps. The incident energy fluence of the pump pulse at the gap was five orders of magnitude lower than the threshold value for reported photo-induced M-R phase transition. The mechanism that makes it possible to reduce the threshold fluence is discussed.

  1. Pump-probe STM light emission spectroscopy for detection of photo-induced semiconductor-metal phase transition of VO2.

    PubMed

    Sakai, Joe; Katano, Satoshi; Kuwahara, Masashi; Uehara, Yoichi

    2017-10-11

    We attempted to observe pump-probe scanning tunneling microscopy (STM)-light emission (LE) from a VO 2 thin film grown on a rutile TiO 2 (0 0 1) substrate, with an Ag tip fixed over a semiconducting domain. Laser pulses from a Ti:sapphire laser (wavelength 920 nm; pulse width less than 1.5 ps) irradiated the tip-sample gap as pump and probe light sources. With a photon energy of 2.7 eV, suggesting phase transition from semiconducting monoclinic (M) to metallic rutile (R) phases in relation to the electronic band structure, faint LE was observed roughly 30 ps after the irradiation of the pump pulse, followed by retention for roughly 20 ps. The incident energy fluence of the pump pulse at the gap was five orders of magnitude lower than the threshold value for reported photo-induced M-R phase transition. The mechanism that makes it possible to reduce the threshold fluence is discussed.

  2. Investigation of local modification and luminescence of a carbon nanotube by scanning tunneling microscopy

    NASA Astrophysics Data System (ADS)

    Katano, Satoshi; Fujita, Hiroto; Uehara, Yoichi

    2018-01-01

    We have studied the nanoscale luminescence from a multiwalled carbon nanotube (CNT) adsorbed on Au(111) using a scanning tunneling microscope (STM). STM images revealed that a number of isolated chains of CNTs can be deposited by dry contact transfer while keeping the surface clean. By injecting tunneling electrons from the STM tip to the CNT, we observed STM light emission (STM-LE) from the CNT in the visible-light range, showing electronic transitions between the bands associated with the van Hove singularity in the density of states of the CNT. The STM-LE spectrum was obviously changed after introducing the local defect created by the STM tip, indicating the controllability of the nanoscale luminescence within a single chain of a CNT.

  3. Three-finger tracheal palpation to guide endotracheal tube depth in children.

    PubMed

    Gamble, Jonathan J; McKay, William P; Wang, Andrew F; Yip, Kinsha A; O'Brien, Jennifer M; Plewes, Christopher E

    2014-10-01

    Accurate endotracheal tube (ETT) depth is critical, especially in children. The current tools used to guide appropriate ETT depth have significant limitations. To evaluate the utility of tracheal palpation in the neck to guide appropriate ETT placement in children. A prospective observational study with a convenience sample of 50 children was conducted. During intubation, an investigator palpated the trachea with three fingertips side-by-side extending upward from the suprasternal notch. The anesthesiologist advanced the ETT slowly until palpated at the sternal notch. The investigator stated ETT palpation certainty as 'strongly felt', 'weakly felt', or 'not felt.' Final ETT position was determined by bronchoscopy and categorized as 'ETT too shallow' (tip in proximal ¼ of trachea), 'ETT too deep' (tip in distal ¼ of trachea), or 'ETT placement satisfactory' (between those extremes). Thirty boys and 20 girls undergoing dental surgery with nasal intubation were recruited (median age 4.4 years; range 2.0-10.8). The ETT (all ≥4 mm ID) was palpable at the sternal notch in all patients: 46 of 50 strongly palpable and 4 of 50 weakly palpable. The experimental methods led to satisfactory ETT placement in 49 of 50 patients, too deep in 1 of 50 patients. Compared with the Pediatrics Advanced Life Support (PALS) predictive formula, satisfactory placement would have been 41 of 50 patients (P < 0.008). Number needed to treat is 6.3 for improvement over the PALS method. The use of tracheal palpation to guide ETT placement has excellent clinical performance and better guides appropriate ETT depth than the PALS formula in our study population. © 2014 John Wiley & Sons Ltd.

  4. Tolerancing the alignment of large-core optical fibers, fiber bundles and light guides using a Fourier approach.

    PubMed

    Sawyer, Travis W; Petersburg, Ryan; Bohndiek, Sarah E

    2017-04-20

    Optical fiber technology is found in a wide variety of applications to flexibly relay light between two points, enabling information transfer across long distances and allowing access to hard-to-reach areas. Large-core optical fibers and light guides find frequent use in illumination and spectroscopic applications, for example, endoscopy and high-resolution astronomical spectroscopy. Proper alignment is critical for maximizing throughput in optical fiber coupling systems; however, there currently are no formal approaches to tolerancing the alignment of a light-guide coupling system. Here, we propose a Fourier alignment sensitivity (FAS) algorithm to determine the optimal tolerances on the alignment of a light guide by computing the alignment sensitivity. The algorithm shows excellent agreement with both simulated and experimentally measured values and improves on the computation time of equivalent ray-tracing simulations by two orders of magnitude. We then apply FAS to tolerance and fabricate a coupling system, which is shown to meet specifications, thus validating FAS as a tolerancing technique. These results indicate that FAS is a flexible and rapid means to quantify the alignment sensitivity of a light guide, widely informing the design and tolerancing of coupling systems.

  5. Tolerancing the alignment of large-core optical fibers, fiber bundles and light guides using a Fourier approach

    PubMed Central

    Sawyer, Travis W.; Petersburg, Ryan; Bohndiek, Sarah E.

    2017-01-01

    Optical fiber technology is found in a wide variety of applications to flexibly relay light between two points, enabling information transfer across long distances and allowing access to hard-to-reach areas. Large-core optical fibers and light guides find frequent use in illumination and spectroscopic applications; for example, endoscopy and high-resolution astronomical spectroscopy. Proper alignment is critical for maximizing throughput in optical fiber coupling systems, however, there currently are no formal approaches to tolerancing the alignment of a light guide coupling system. Here, we propose a Fourier Alignment Sensitivity (FAS) algorithm to determine the optimal tolerances on the alignment of a light guide by computing the alignment sensitivity. The algorithm shows excellent agreement with both simulated and experimentally measured values and improves on the computation time of equivalent ray tracing simulations by two orders of magnitude. We then apply FAS to tolerance and fabricate a coupling system, which is shown to meet specifications, thus validating FAS as a tolerancing technique. These results indicate that FAS is a flexible and rapid means to quantify the alignment sensitivity of a light guide, widely informing the design and tolerancing of coupling systems. PMID:28430250

  6. Common-path low-coherence interferometry fiber-optic sensor guided microincision

    PubMed Central

    Zhang, Kang; Kang, Jin U.

    2011-01-01

    We propose and demonstrate a common-path low-coherence interferometry (CP-LCI) fiber-optic sensor guided precise microincision. The method tracks the target surface and compensates the tool-to-surface relative motion with better than ±5 μm resolution using a precision micromotor connected to the tool tip. A single-fiber distance probe integrated microdissector was used to perform an accurate 100 μm incision into the surface of an Intralipid phantom. The CP-LCI guided incision quality in terms of depth was evaluated afterwards using three-dimensional Fourier-domain optical coherence tomography imaging, which showed significant improvement of incision accuracy compared to free-hand-only operations. PMID:21950912

  7. [Echo-guided radiofrequency percutaneous ablation of hepatocellular carcinoma in cirrhosis using a cooled needle].

    PubMed

    Marone, G; Francica, G; D'Angelo, V; Iodice, G; Pastore, P; Altamura, G; Cusati, B; Siani, A

    1998-06-01

    Radiofrequency hyperthermia using the newly-developed "cooled-tip" needle is one of the latest US-guided percutaneous treatments of hepatocellular carcinoma arising in cirrhosis. The continuous cooling of the needle tip allows tissue heating and necrosis far from the electrode without tissue charring, which was the major drawback of the old monopolar technique. Herein we report our preliminary results on feasibility and effectiveness of the thermoablation of mono- or paucifocal hepatocellular carcinoma with the cooled-tip needle. November, 1996, to January, 1998, we treated thirteen cirrhotic patients (mean age 69.5 yrs, 10 men, 12 HCV-positive; 11 in Child's Class A and 2 in Class B) with 19 hepatocellular carcinoma nodules (mean diameter: 27 mm; range: 10-41 mm; 6 with diameter > 3 cm). None of the patients had portal thrombosis and/or extrahepatic spread. We used a radiofrequency generator (100 W power) connected to an 18 G perfusion electrode needle with an exposed tip of 2-3 cm. The circuit is closed through a dispersive electrode positioned under the patient's thighs. A peristaltic pump infuses a chilled (2-5 degrees C) saline solution to guarantee the continuous cooling of the needle tip. The needle was placed into target lesions under US guidance. The interventional procedure was carried out under general anesthesia using Propofol without intubation. Dynamic CT (more recently with the helical technique) was carried out 15-20 days after thermoablation to assess treatment efficacy. In all, 31 thermal injuries (at 1000-1200 mA for 10-15 minutes) were caused in 21 sessions in the 19 hepatocellular carcinoma nodules (mean: 1.5 lesions per nodule and 1.6 sessions per patient). Complete necrosis as assessed at dynamic CT (no enhancement during the arteriographic phase) was achieved in 16 of 19 nodules (84%). No side-effects occurred. During the follow-up (median: 11 months) no death occurred and five patients had recurrent hepatocellular carcinoma appearing either as single nodule or as multinodular liver involvement. In our experience radiofrequency hyperthermia with the cooled-tip needle permits effective and safe percutaneous ablation of HCC in cirrhosis. In addition, treatment time is short and lesions > 3 cm can be treated. Further experience is needed to better define the role of percutaneous thermoablation in the treatment strategy of hepatocellular carcinoma.

  8. Twelve tips for blueprinting.

    PubMed

    Coderre, Sylvain; Woloschuk, Wayne; McLaughlin, Kevin

    2009-04-01

    Content validity is a requirement of every evaluation and is achieved when the evaluation content is congruent with the learning objectives and the learning experiences. Congruence between these three pillars of education can be facilitated by blueprinting. Here we describe an efficient process for creating a blueprint and explain how to use this tool to guide all aspects of course creation and evaluation. A well constructed blueprint is a valuable tool for medical educators. In addition to validating evaluation content, a blueprint can also be used to guide selection of curricular content and learning experiences.

  9. Chemical composition of felt-tip pen inks.

    PubMed

    Germinario, Giulia; Garrappa, Silvia; D'Ambrosio, Valeria; van der Werf, Inez Dorothé; Sabbatini, Luigia

    2018-01-01

    Felt-tip pens are frequently used for the realization of sketches, drawings, architectural projects, and other technical designs. The formulations of these inks are usually rather complex and may be associated to those of modern paint materials where, next to the binding medium and pigments/dyes, solvents, fillers, emulsifiers, antioxidants, plasticizers, light stabilizers, biocides, and so on are commonly added. Felt-tip pen inks are extremely sensitive to degradation and especially exposure to light may cause chromatic changes and fading. In this study, we report on the complete chemical characterization of modern felt-tip pen inks that are commercially available and commonly used for the realization of artworks. Three brands of felt-tip pens (Faber-Castell, Edding, and Stabilo) were investigated with complementary analytical techniques such as thin-layer chromatography (TLC), VIS-reflectance spectroscopy, μ-Raman spectroscopy, surface-enhanced Raman spectroscopy (SERS), pyrolysis-gas chromatography-mass spectrometry (Py-GC-MS), GC-MS, and Fourier transform infrared (FTIR) spectroscopy. The use of TLC proved to be very powerful in the study of complex mixtures of synthetic dyes. First derivatives of the reflectance spectra acquired on the TLC spots were useful in the preliminary identification of the dye, followed by Raman spectroscopy and SERS, which allowed for the unambiguous determination of the chemical composition of the pigments (phthalocyanines, dioxazines, and azo pigments) and dyes (azo dyes, triarylmethanes, xanthenes). FTIR spectroscopy was used especially for the detection of additives, as well as for confirming the nature of solvents and dyes/pigments. Finally, (Py-)GC-MS data provided information on the binders (styrene-acrylic resins, plant gums), solvents, and additives, as well as on pigments and dyes.

  10. Nano-cone optical fiber array sensors for MiRNA profiling

    NASA Astrophysics Data System (ADS)

    Wang, Yunshan; Senapati, Satyajyoti; Stoddart, Paul; Howard, Scott; Chang, Hsueh-Chia

    2013-09-01

    Up/down regulation of microRNA panels has been correlated to cardiovascular diseases and cancer. Frequent miRNA profiling at home can hence allow early cancer diagnosis and home-use chronic disease monitoring, thus reducing both mortality rate and healthcare cost. However, lifetime of miRNAs is less than 1 hour without preservation and their concentrations range from pM to mM. Despite rapid progress in the last decade, modern nucleic acid analysis methods still do not allow personalized miRNA profiling---Real-time PCR and DNA micro-array both require elaborate miRNA preservation steps and expensive equipment and nano pore sensors cannot selectively quantify a large panel with a large dynamic range. We report a novel and low-cost optical fiber sensing platform, which has the potential to profile a panel of miRNA with simple LED light sources and detectors. The individual tips of an optical imaging fiber bundle (mm in diameter with 7000 fiber cores) were etched into cones with 10 nm radius of curvature and coated with Au. FRET (Forster Resonant Energy Transfer) hairpin oligo probes, with the loop complementary to a specific miRNA that can release the hairpin, were functionalized onto the conic tips. Exciting light in the optical fiber waveguide is optimally coupled to surface plasmonics on the gold surface, which then converges to the conic tips with two orders of magnitude enhancement in intensity. Unlike nanoparticle plasmonics, tip plasmonics can be excited over a large band width and hence the plasmonic enhanced fluorescence signal of the FRET reporter is also focused towards the tip--- and is further enhanced with the periodic resonant grid of the fiber array which gives rise to pronounced standing wave interference patterns. Multiplexing is realized by functionalizing different probes onto one fiber bundle using a photoactivation process.

  11. An extraocular non-invasive transscleral LED-endoilluminator for eye speculum integration.

    PubMed

    Kölbl, Philipp Simon; Lindner, Christoph; Lingenfelder, Christian; Deuchler, Svenja; Singh, Pankaj; Koch, Frank; Hessling, Martin

    2015-09-01

    Conventional chandelier-endoilluminators used for pars-plana vitrectomy consist of a light-emitting tip attached to an optical fibre. The tip requires introduction into the ocular space through an incision. To achieve complete illumination of the intraocular space, the introduction of more than just one tip is sometimes necessary. An extraocular vitreoretinal LED-endoilluminator discussed in this paper represents a new approach to illuminate the intraocular space. The light source is integrated into a speculum and firmly apposed to the sclera. This approach offers the advantage of effectively illuminating the interior of the eye even though the procedure is non-invasive. Furthermore, this approach significantly reduces the risk of damage to the retina by phototoxic effects. A round white LED was used as a light source. By integrating the light source into a speculum, the LED was firmly held against the sclera. Thus, the ocular space was illuminated transsclerally. As a result, indirect uniform illumination of the complete intraocular space was achieved. The prototype was developed considering the relevant international standards. Porcine eyes were used because their properties are similar to those of human eyes. Porcine eyes could be acceptably illuminated with the selected LED. The LED-endoilluminator conforms with international standards for endoillumination. Thus, possible photochemical and thermal risks are considered and reduced to a minimum. A novel LED-endoilluminator which can be attached to a speculum was developed. The system does not need any connection to an external light source and, consequently, also avoids usage of an optical fibre. Regular and uniform illumination of the intraocular space was achieved by transmitted and scattered visible irradiation, avoiding an incision. The duration of potential light exposure, compared to existing illumination systems, can be significantly increased. This is also true when the illuminator is not directly placed over the pars-plana and the distance to the retina is reduced. Only a part of the light reaches the retina and the fraction of short wavelength becomes very small. Increased safety of the system results from now being able to increase the exposure time and reduce phototoxic stress to the retina.

  12. Transparent Solar Concentrator for Flat Panel Display

    NASA Astrophysics Data System (ADS)

    Yeh, Chia-Hung; Chang, Fuh-Yu; Young, Hong-Tsu; Hsieh, Tsung-Yen; Chang, Chia-Hsiung

    2012-06-01

    A new concept of the transparent solar concentrator for flat panel display is experimentally demonstrated without adversely affecting the visual effects. The solar concentrator is based on a solar light-guide plate with micro prisms, not only increasing the absorption area of solar energy but also enhancing the conversion efficiency. The incident light is guided by the designed solar light-guide plate according to the total internal reflection (TIR), and converted into electrical power by photovoltaic solar cells. The designed transparent solar concentrator was made and measured with high transparency, namely 94.8%. The developed solar energy system for display can store energy and supply the bias voltage to light on two light-emitting diodes (LEDs) successfully.

  13. Quasi-linearly polarized hybrid modes in tapered and metal-coated tips with circular apertures: understanding the functionality of aperture tips

    NASA Astrophysics Data System (ADS)

    Tugchin, B. N.; Janunts, N.; Steinert, M.; Dietrich, K.; Kley, E. B.; Tünnermann, A.; Pertsch, T.

    2017-06-01

    In this study, we investigate analytically and experimentally the roles of quasi-linearly polarized (LP), hybrid, plasmonic and photonic modes in optical detection and excitation with aperture tips in scanning near-field optical microscopy. Aperture tips are tapered and metal-coated optical fibers where small circular apertures are made at the apex. In aperture tips, there exist plasmonic modes that are bound at the interface of the metal cladding to the inner dielectric fiber and photonic modes that are guided in the area of the increased index in the dielectric fiber core. The fundamental photonic mode, although excited by the free-space Gaussian beam, experiences cutoff and turns into an evanescent mode. The photonic mode also becomes lossier than the plasmonic mode toward the tip aperture, and its power decay due to absorption and reflection is expected to be at least 10-9. In contrast, the fundamental plasmonic mode has no cutoff and thus reaches all the way to the tip aperture. Due to the non-adiabaticity of both modes’ propagations through the taper below a core radius of 600 nm, there occurs coupling between the modes. The transmission efficiency of the plasmonic mode, including the coupling efficiency and the propagation loss, is expected to be about 10-6 that is at least 3 orders of magnitude larger than that of the photonic mode. Toward the tip aperture, the longitudinal field of the photonic mode becomes stronger than the transverse ones while the transverse fields always dominate for the plasmonic mode. Experimentally, we obtain polarization resolved images of the near-field at the tip aperture and compare with the x- and y-components of the fundamental quasi-LP plasmonic and photonic modes. The results show that not only the pattern but also the intensity ratios of the x- and y-components of the aperture near-field match with that of the fundamental plasmonic mode. Consequently, we conclude that only the plasmonic mode reaches the tip aperture and thus governs the near-field interaction outside the tip aperture. Our conclusion remains valid for all aperture tips regardless of the cladding metal type that mainly influences the total transmission efficiency of the aperture tip.

  14. Comparison of different types of phacoemulsification tips. I. Quantitative analysis of elemental composition and tip surface microroughness.

    PubMed

    Tsaousis, Konstantinos T; Werner, Liliana; Perez, Jesus Paulo; Li, He J; Reiter, Nicholas; Guan, Jia J; Mamalis, Nick

    2016-09-01

    To evaluate the elemental composition of phacoemulsification tips and their surface roughness in the microscale. John A. Moran Eye Center and Utah Nanofab, College of Engineering, University of Utah, Salt Lake City, Utah, USA. Experimental study. Seven types of phacoemulsification tips were studied. The phaco tips were examined through energy-dispersive x-ray spectroscopy (EDS) and x-ray photoelectron spectroscopy (XPS) for elemental composition. In addition, the roughness of the opening in all tips was assessed through 3-dimensional white-light interferometry. Elemental analysis showed considerable differences in the surface layers between manufacturers. Alcon tips had a thinner oxidized titanium (Ti) layer in their surface. Through XPS, vanadium was not detected in the superficial layers of any tip, but only in deeper levels. The microroughness surface analysis showed comparable results regarding their root-mean-square (RMS) metric. Maximum peak valley distance values varied and appeared to be dependent on the quality of material process rather than the material itself. Phacoemulsification tips are made of Ti alloys and showed differences between models, especially regarding their composition in the superficial layers. Their opening end roughness showed an overall appropriate RMS value of less than 1.0 μm in all cases. The existence of small defected areas highlights the importance of adequate quality control of these critical surgical instruments. None of the authors has a financial or proprietary interest in any material or method mentioned. Copyright © 2016 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  15. Predictability of orthodontic movement with orthodontic aligners: a retrospective study.

    PubMed

    Lombardo, Luca; Arreghini, Angela; Ramina, Fabio; Huanca Ghislanzoni, Luis T; Siciliani, Giuseppe

    2017-11-13

    The aim of this study was to evaluate the predictability of F22 aligners (Sweden & Martina, Due Carrare, Italy) in guiding teeth into the positions planned using digital orthodontic setup. Sixteen adult patients (6 males and 10 females, mean age 28 years 7 months) were selected, and a total of 345 teeth were analysed. Pre-treatment, ideal post-treatment-as planned on digital setup-and real post-treatment models were analysed using VAM software (Vectra, Canfield Scientific, Fairfield, NJ, USA). Prescribed and real rotation, mesiodistal tip and vestibulolingual tip were calculated for each tooth and, subsequently, analysed by tooth type (right and left upper and lower incisors, canines, premolars and molars) to identify the mean error and accuracy of each type of movement achieved with the aligner with respect to those planned using the setup. The mean predictability of movements achieved using F22 aligners was 73.6%. Mesiodistal tipping showed the most predictability, at 82.5% with respect to the ideal; this was followed by vestibulolingual tipping (72.9%) and finally rotation (66.8%). In particular, mesiodistal tip on the upper molars and lower premolars were achieved with the most predictability (93.4 and 96.7%, respectively), while rotation on the lower canines was the least efficaciously achieved (54.2%). Without the use of auxiliaries, orthodontic aligners are unable to achieve programmed movement with 100% predictability. In particular, although tipping movements were efficaciously achieved, especially at the molars and premolars, rotation of the lower canines was an extremely unpredictable movement.

  16. Negative regulators of vessel patterning.

    PubMed

    Suchting, Steven; Freitas, Catarina; le Noble, Ferdinand; Benedito, Rui; Bréant, Christiane; Duarte, Antonio; Eichmann, Anne

    2007-01-01

    Blood vessels and nerves are structurally similar, complex branched networks that require guidance to ensure their proper positioning in the body. Recent studies have demonstrated that specialized endothelial cells, resembling axonal growth cones, are located at the tips of growing capillaries. These endothelial tip cells guide outgrowing capillaries in response to gradients of extracellular matrix-bound vascular endothelial growth factor (VEGF). Here we show that endothelial tip cell formation and vessel branching are negatively regulated by the Notch ligand Delta-like 4 (Dll4). Heterozygous deletion of Dll4 or pharmacological inhibition of Notch signalling using gamma-secretase inhibitor revealed a striking vascular phenotype, with greatly increased numbers of filopodia-extending endothelial tip cells and increased expression of tip cell marker genes compared to controls. Filopodia extension in Dll4+/- retinal vessels required VEGF and was inhibited when VEGF signalling was blocked. While VEGF expression was not significantly altered in Dll4+- retinas, Dll4+/- vessels showed increased expression of VEGF Receptor 2 and decreased expression of VEGF Receptor 1 compared to wildtype, suggesting that they could be more responsive to VEGF stimulation. In addition, expression of Dll4 in wildtype tip cells was itself decreased when VEGF signalling was blocked, indicating that Dll4 may act downstream of VEGF as a 'brake' on VEGF-mediated angiogenic sprouting. Taken together, these data reveal Dll4 as a novel negative regulator of vascular sprouting and vessel branching that is required for normal vascular network formation during development.

  17. Hydrophilic guidewires: evaluation and comparison of their properties and safety.

    PubMed

    Torricelli, Fabio Cesar Miranda; De, Shubha; Sarkissian, Carl; Monga, Manoj

    2013-11-01

    To compare physical and mechanical properties of 10 commercially available hydrophilic guidewires. In vitro testing was performed to evaluate 10 different straight hydrophilic guidewires (5 regular and 5 stiff wires): Glidewire, NiCore, EZ Glider, Hiwire, and Zipwire. The forces required for tip perforation, tip bending, shaft bending, and friction during movement were measured for all 10 wires. The tip contour was measured using high power light microscopy. The Glidewire required the greatest force to perforate our model (P = .01). The EZ Glider, Zipwire, and Glidewire had the lowest tip bending forces (P <.001). The Glidewire had the stiffest shaft (P <.001). The EZ Glider and Glidewire required the greatest forces in the friction test (P <.001). Regarding the stiff guidewires, the GlidewireS required the greatest force in the perforation test (P ≤.05). The GlidewireS and EZ GliderS required the lowest tip bending force (P ≤.004). The ZipwireS and NiCoreS had the stiffest shafts (P ≤.01). The GlidewireS required the greatest force in the friction test (P <.001). Measurement of the tip contour showed the Zipwire, HiwireS, and EZ GliderS had the roundest tips. Each wire has unique properties with advantages and disadvantages. The Glidewires (both stiff and regular) have the lowest potential for perforation, although they are less slippery. The Glidewire and EZ Glider required the least tip force to bend around a point of obstruction. Copyright © 2013 Elsevier Inc. All rights reserved.

  18. Photonic surgery with noncoherent light

    NASA Astrophysics Data System (ADS)

    Feuermann, Daniel; Gordon, Jeffrey M.; Ng, Tuck Wah

    2006-03-01

    Extensive photothermal surgical effects have been generated with artificial noncoherent light. Our ex vivo experiments produced the same type and extent of tissue damage ordinarily achieved with laser fiber-optic surgery, at comparable surgical efficacy, the motivation being the possibility of supplanting surgical lasers with a potentially far less expensive device. Maximum-flux optics reconstitute the immense power density at the core of an ultrabright discharge lamp inside an optical fiber the distal tip of which couples light into the organ.

  19. [Detection of single-walled carbon nanotube bundles by tip-enhanced Raman spectroscopy].

    PubMed

    Wu, Xiao-Bin; Wang, Jia; Wang, Rui; Xu, Ji-Ying; Tian, Qian; Yu, Jian-Yuan

    2009-10-01

    Raman spectroscopy is a powerful technique in the characterization of carbon nanotubes (CNTs). However, this spectral method is subject to two obstacles. One is spatial resolution, namely the diffraction limits of light, and the other is its inherent small Raman cross section and weak signal. To resolve these problems, a new approach has been developed, denoted tip-enhanced Raman spectroscopy (TERS). TERS has been demonstrated to be a powerful spectroscopic and microscopic technique to characterize nanomaterial or nanostructures. Excited by a focused laser beam, an enhanced electric field is generated in the vicinity of a metallic tip because of the surface plasmon polariton (SPP) and lightening rod effect. Consequently, Raman signal from the sample area illuminated by the enhanced field nearby the tip is enhanced. At the same time, the topography is obtained in the nanometer scale. The exact corresponding relationship between the localized Raman and the topography makes the Raman identification at the nanometer scale to be feasible. In the present paper, based on an inverted microscope and a metallic AFM tip, a tip-enhanced Raman system was set up. The radius of the Au-coated metallic tip is about 30 nm. The 532 nm laser passes through a high numerical objective (NA0.95) from the bottom to illuminate the tip to excite the enhanced electric field. Corresponding with the AFM image, the tip-enhanced near-field Raman of a 100 nm diameter single-walled carbon nanotube (SWNT) bundles was obtained. The SWNTs were prepared by arc method. Furthermore, the near-field Raman of about 3 SWNTs of the bundles was received with the spatial resolution beyond the diffraction limit. Compared with the far-field Raman, the enhancement factor of the tip-enhanced Raman is more than 230. With the super-diffraction spatial resolution and the tip-enhanced Raman ability, tip-enhanced Raman spectroscopy will play an important role in the nano-material and nano-structure characterization.

  20. Silica aerogel core waveguide.

    PubMed

    Grogan, M D W; Leon-Saval, S G; England, R; Birks, T A

    2010-10-11

    We have selectively filled the core of hollow photonic crystal fibre with silica aerogel. Light is guided in the aerogel core, with a measured attenuation of 0.2 dB/cm at 1540 nm comparable to that of bulk aerogel. The structure guides light by different mechanisms depending on the wavelength. At long wavelengths the effective index of the microstructured cladding is below the aerogel index of 1.045 and guidance is by total internal reflection. At short wavelengths, where the effective cladding index exceeds 1.045, a photonic bandgap can guide the light instead. There is a small region of crossover, where both index- and bandgap-guided modes were simultaneously observed.

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