A resolution congratulating the people of the Republic of Lithuania on the Act of the Re-Establishment of the State of Lithuania, or Act of March 11, and celebrating the rich history of Lithuania.

THOMAS, 111th Congress

Sen. Durbin, Richard J. [D-IL

2010-03-04

Senate - 03/04/2010 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

Cost-effectiveness of 12- and 15-year-old girls' human papillomavirus 16/18 population-based vaccination programmes in Lithuania.

PubMed

Vanagas, Giedrius; Padaiga, Zilvinas; Kurtinaitis, Juozas; Logminiene, Zeneta

2010-08-01

There is a large difference in the prevalence of cervical cancer between European countries. Between European Union countries, cervical cancer is the most prevalent in Lithuania. Currently we have available vaccines for different types of human papillomavirus virus (HPV), but we lack evidence on how the vaccination would be cost-effective in low-resource Eastern European countries like Lithuania. To create a simulation model for the Lithuanian population; to estimate epidemiological benefits and cost-effectiveness for a HPV16/18 vaccination programme in Lithuania. For the cost-effectiveness analysis, we used Lithuanian population mathematical simulation and epidemiological data modelling. We performed comparative analysis of annual vaccination programmes of 12-year-old or 15-year-old girls at different vaccine penetration levels. Lithuanian female population at all age groups. A vaccination programme in Lithuania would gain an average of 35.6 life years per death avoided. Vaccinated girls would experience up to 76.9% overall reduction in incidence of cervical cancers, 80.8% reduction in morbidity and 77.9% reduction in mortality over their lifetime. Cost per life year gained with different vaccine penetration levels would range from 2167.41 Euros to 2999.74 Euros. HPV vaccination in Lithuania would have a very positive impact on the epidemiological situation and it would be cost-effective at all ranges of vaccine penetration. Vaccination in Lithuania in the long term potentially could be more cost-effective due to avoiding early disease onset and lower accumulation of period costs.

A catalogue of Lithuanian beetles (Insecta, Coleoptera)

PubMed Central

Tamutis, Vytautas; Tamutė, Brigita; Ferenca, Romas

2011-01-01

Abstract This paper presents the first complete and updated list of all 3597 species of beetles (Insecta: Coleoptera) belonging to 92 familiesfound and published in Lithuania until 2011, with comments also provided on the main systematic and nomenclatural changes since the last monographic treatment in two volumes (Pileckis and Monsevičius 1995, 1997). The introductory section provides a general overview of the main features of the territory of Lithuania, the origins and formation of the beetle fauna and their conservation, the faunistic investigations in Lithuania to date revealing the most important stages of the faunistic research process with reference to the most prominent scientists, an overview of their work, and their contribution to Lithuanian coleopteran faunal research. Species recorded in Lithuania by some authors without reliable evidence and requiring further confirmation with new data are presented in a separate list, consisting of 183 species. For the first time, analysis of errors in works of Lithuanian authors concerning data on coleopteran fauna has been conducted and these errors have been corrected. All available published and Internet sources on beetles found in Lithuania have been considered in the current study. Over 630 literature sources on species composition of beetles, their distribution in Lithuania and neighbouring countries, and taxonomic revisions and changes are reviewed and cited. An alphabetical list of these literature sources is presented. After revision of public beetle collections in Lithuania, the authors propose to remove 43 species from the beetle species list of the country on the grounds, that they have been wrongly identified or published by mistake. For reasons of clarity, 19 previously noted but later excluded species are included in the current checklist with comments. Based on faunal data from neighbouring countries, species expected to occur in Lithuania are matnioned. In total 1390 species are attributed to this category and data on their distribution in neighbouring countries is presented. Completion of this study provides evidence that the Lithuanian coleopteran fauna has yet to be completely investigated and it is estimated that approximately 28 % of beetle species remain undiscovered in Lithuania. More than 85% of beetle species expected for Lithuania have been found in the following families: Cerylonidae, Geotrupidae, Haliplidae, Kateridae, Lycidae, Lucanidae, Mycetophagidae, Scarabaeidae and Silphidae. In families with few species such as Alexiidae, Boridae, Byturidae, Dascilidae, Drilidae, Eucinetidae, Lampyridae, Lymexilidae, Megalopodidae, Nemonychidae, Nosodendridae, Noteridae, Orsodacnidae, Pyrochroidae, Pythidae, Psephenidae, Rhysodidae, Sphaeritidae, Sphaeriusidae, Sphindidae, Stenotrahelidae and Trogidae, all possible species have already been discovered. However in some beetle families such as Aderidae, Bothrideridae, Eucnemidae, Laemoploeidae, Mordellidae, Ptiliidae, Scraptidae and Throscidae less than 50% of all possible species are known. At present the beetle species recorded in Lithuania belong to 92 families, with species from 9 other families such as Agyrtidae, Biphylidae, Deradontidae, Mycteridae, Ochodaeidae, Phleophilidae, Phloeostichidae, Prostomidae, Trachypachidae are expected to be found. A bibliography and a index of subfamily and genus levels are provided. The information published in the monograph will serve to further faunistic and distribution research of beetles and will help to avoid confusion in the identificatation of coleopteran fauna of Lithuania. PMID:22461725

Regional Patterns of Ethnicity in Nova Scotia: A Geographical Study. Ethnic Heritage Series, Volume VI.

ERIC Educational Resources Information Center

Millward, Hugh A.

In this sixth volume of the Ethnic Heritage Series, the pattern of ethnicity in Nova Scotia (Canada) is examined by deriving indices of diversity for counties and larger towns. The historical development of ethnic patterns from 1767 to 1971 and recent changes in the ethnic pattern are discussed. Ethnic origin data is mapped for 1871 and 1971 and…

Onshore Wind Farms: Value Creation for Stakeholders in Lithuania

NASA Astrophysics Data System (ADS)

Burinskienė, Marija; Rudzkis, Paulius; Kanopka, Adomas

With the costs of fossil fuel consistently rising worldwide over the last decade, the development of green technologies has become a major goal in many countries. Therefore the evaluation of wind power projects becomes a very important task. To estimate the value of the technologies based on renewable resources also means taking into consideration social, economic, environmental, and scientific value of such projects. This article deals with economic evaluation of electricity generation costs of onshore wind farms in Lithuania and the key factors that have influence on wind power projects and offer a better understanding of social-economic context behind wind power projects. To achieve these goals, this article makes use of empirical data of Lithuania's wind power farms as well as data about the investment environment of the country.Based on empirical data of wind power parks, the research investigates the average wind farm generation efficiency in Lithuania. Employing statistical methods the return on investments of wind farms in Lithuania is calculated. The value created for every party involved and the total value of the wind farm is estimated according to Stakeholder theory.

Canavan Disease

MedlinePlus

... Ashkenazi Jews from eastern Poland, Lithuania, and western Russia, and among Saudi Arabians. Canavan disease can be ... Ashkenazi Jews from eastern Poland, Lithuania, and western Russia, and among Saudi Arabians. Canavan disease can be ...

Ukrainians in America: Contributions to America, Relationship to Homeland, Integration into American Life, Retention of Ethnicity in America. Ethnic Heritage in America: Curriculum Materials in Elementary School Social Studies on Greeks, Jews, Lithuanians, and Ukrainians.

ERIC Educational Resources Information Center

Chicago Consortium for Inter-Ethnic Curriculum Development, IL.

This ethnic heritage unit is about Ukrainians in the United States. The first section presents basic facts, such as a map of Ukraine, map of Eastern Europe, facts about Ukraine, principal dates in Ukrainian history, ten outstanding figures in modern Ukrainian history, milestones of Ukrainian communities in the United States, bibliography about…

Jews in America: Contributions to America, Relationship to Homeland, Integration into American Life, Retention of Ethnicity in America. Ethnic Heritage in America: Curriculum Materials in Elementary School Social Studies on Greeks, Jews, Lithuanians, Ukrainians.

ERIC Educational Resources Information Center

Chicago Consortium for Inter-Ethnic Curriculum Development, IL.

This ethnic heritage unit is about Jews in the United States. The first section presents basic facts, such as a map of Israel, map of Eastern Europe, facts about Israel, a bibliography about Jews, and a list of Jewish organizations in the United States. The second section discusses early Jewish settlement in North America, Jewish contributions to…

NASA Administrator Welcomes Minister of Economy

NASA Image and Video Library

2014-02-18

NASA Administrator Charles Bolden, left, welcomes Lithuania's Minister of Economy Evaldas Gustas to NASA Headquarters to discuss potential collaborative space activities between NASA and the Republic of Lithuania, Tuesday, Feb. 18, 2014 in Washington.

Changes in nursing ethics education in Lithuania.

PubMed

Toliusiene, Jolanta; Peicius, Eimantas

2007-11-01

The post-Soviet scene in Lithuania is one of rapid change in medical and nursing ethics. A short introduction to the current background sets the scene for a wider discussion of ethics in health care professionals' education. Lithuania had to adapt rapidly from a politicized nursing and ethics curriculum to European regulations, and from a paternalistic style of care to one of engagement with choices and dilemmas. The relationships between professionals, and between professionals and patients, are affected by this in particular. This short article highlights these issues and how they impact on all involved.

Renal anemia control in Lithuania: influence of local conditions and local guidelines.

PubMed

Ziginskiene, Edita; Kuzminskis, Vytautas; Petruliene, Kristina; Vaiciuniene, Ruta; Stankuviene, Asta; Bumblyte, Inga Arune

2013-01-01

Erythropoietin stimulating agents had a long haul in Lithuania--we had no epoetin till 1994 and there was no intravenous iron in 2001-2004. The aim of this study was to assess the changes of renal anemia control in hemodialysis patients from early independence of Lithuania till nowadays and to evaluate the link of anemia with hospitalization rates and survival and hemoglobin variability in association with mortality. In December of each year since 1996 all hemodialysis centers have been visited and data has been collected using special questionnaires. The history of renal anemia control in Lithuania was complicated; however, a significant improvement was achieved: 54.7% of hemodialysis patients reached the target hemoglobin; all patients have a possibility of treatment with epoetin and intravenous iron. The involuntary experiment with an intravenous iron occurred in Lithuania because of economic reasons and confirmed the significant role of intravenous iron in the management of renal anemia. Hemoglobin below 100 g/L was associated with a 2.5-fold increase in relative risk of death and 1.7-fold increase in relative risk of hospitalization in Lithuanian hemodialysis patients. Although hemoglobin variability was common in Lithuanian hemodialysis patients, we did not find the association between hemoglobin variability and all-cause mortality in our study.

A novel continuous colour mapping approach for visualization of facial skin hydration and transepidermal water loss for four ethnic groups.

PubMed

Voegeli, R; Rawlings, A V; Seroul, P; Summers, B

2015-12-01

The aim of this exploratory study was to develop a novel colour mapping approach to visualize and interpret the complexity of facial skin hydration and barrier properties of four ethnic groups (Caucasians, Indians, Chinese and Black Africans) living in Pretoria, South Africa. We measured transepidermal water loss (TEWL) and skin capacitance on 30 pre-defined sites on the forehead, cheek, jaw and eye areas of sixteen women (four per ethnic group) and took digital images of their faces. Continuous colour maps were generated by interpolating between each measured value and superimposing the values on the digital images. The complexity of facial skin hydration and skin barrier properties is revealed by these measurements and visualized by the continuous colour maps of the digital images. Overall, the Caucasian subjects had the better barrier properties followed by the Black African subjects, Chinese subjects and Indian subjects. Nevertheless, the two more darkly pigmented ethnic groups had superior skin hydration properties. Subtle differences were seen when examining the different facial sites. There exists remarkable skin capacitance and TEWL gradients within short distances on selected areas of the face. These gradients are distinctive in the different ethnic groups. In contrast to other reports, we found that darkly pigmented skin does not always have a superior barrier function and differences in skin hydration values are complex on the different parts of the face among the different ethnic groups. © 2015 Society of Cosmetic Scientists and the Société Française de Cosmétologie.

The hill forts and castle mounds in Lithuania: interaction between geodiversity and human-shaped landscape

NASA Astrophysics Data System (ADS)

Skridlaite, Grazina; Guobyte, Rimante; Satkunas, Jonas

2015-04-01

Lithuania is famous for its abundant, picturesque hill forts and castle mounds of natural origin. In Lithuania as well as in whole Europe the fortified hills were used as the society dwelling place since the beginning of the Late Bronze Age. Their importance increased when Livonian and Teutonic Orders directed a series of military campaigns against Lithuania with the aim of expansion of Christianity in the region at the end of 1st millennium AD, and they were intensively used till the beginning of the 15th c. when most of them were burned down during fights with the Orders or just abandoned due to the changing political and economical situation. What types of the geodiversity were used for fortified dwellings? The choice in a particular area depended on a variety of geomorphology left behind the retreating ice sheets. High spots dominating their surroundings were of prime interest. In E and SE Lithuania, the Baltic Upland hills marking the eastern margin of the last Weichselian glacier hosted numerous fortified settlements from the end of 2nd millennium BC to the Medieval Ages (Narkunai, Velikuskes etc). In W Lithuania, plateau-like hills of the insular Samogitian Upland had been repeatedly fortified from the beginning of 1st millennium AD to the 14th century (Satrija, Medvegalis etc). Chains of hill forts and castle mounds feature the slopes of glaciofluvial valleys of Nemunas, Neris and other rivers where the slopes were dissected by affluent rivulets and ravines and transformed into isolated, well protected hills (Kernave, Punia, Veliuona etc). Peninsulas and headlands formed by the erosion of fluvial and lacustrine deposits were used in the lowlands, e.g. in central and N Lithuania (Paberze, Mezotne etc). How much the landscape was modified for defense purposes? Long-term erosion and overgrowing vegetation damaged the former fortified sites, however some remains and the archeological excavations allowed their reconstruction. The fortified Bronze Age settlements used naturally-protected sites with only hilltop flattening and small ditches. Wooden fences surrounded the settlements in most cases while stony ditches were used in NW Lithuania (e.g. Ipiltis). From the beginning of 1st millennium AD the fortifications became stronger with multiple rampart-ditch systems and artificial canals. Construction of hill forts with a high-powered fortification system started in 13th c. when wooden castles surrounded by rampart-trench systems appeared. What is a protection status for the hill forts and castle mounds? Near 1000 sites are protected by the Lithuanian State as historical monuments. Many of them are cleaned from vegetation, supplied with an infrastructure and arranged for tourism purposes. Some are parts of the nature or historical reserves or regional and national parks. However, apart from a few cases, geology of the hill forts and other strongholds in Lithuania is yet poorly known. Needless to say, the hill forts and castle mounds are quite a unique and attractive feature of the Lithuanian landscape. For defense purposes, the ancient European countries relied more on stone and brick castles than on steepness of high hill slopes as it was in case of Lithuania.

Social Partnership in Accrediting Lithuanian VET Qualifications

ERIC Educational Resources Information Center

Tutlys, Vidmantas; Kaminskiene, Lina

2008-01-01

This article examines social partnership in accrediting qualifications in Lithuania. It defines the factors influencing social partnership and surveys future development perspectives, referring to the creation and implementation of the national qualifications system in Lithuania. Social partnership in qualifications accreditation is regarded as a…

Teamwork in primary care: perspectives of general practitioners and community nurses in Lithuania

PubMed Central

2013-01-01

Background A team approach in primary care has proven benefits in achieving better outcomes, reducing health care costs, satisfying patient needs, ensuring continuity of care, increasing job satisfaction among health providers and using human health care resources more efficiently. However, some research indicates constraints in collaboration within primary health care (PHC) teams in Lithuania. The aim of this study was to gain a better understanding of the phenomenon of teamwork in Lithuania by exploring the experiences of teamwork by general practitioners (GPs) and community nurses (CNs) involved in PHC. Methods Six focus groups were formed with 29 GPs and 27 CNs from the Kaunas Region of Lithuania. Discussions were recorded and transcribed verbatim. A thematic analysis of these data was then performed. Results The analysis of focus group data identified six thematic categories related to teamwork in PHC: the structure of a PHC team, synergy among PHC team members, descriptions of roles and responsibilities of team members, competencies of PHC team members, communications between PHC team members and the organisational background for teamwork. These findings provide the basis for a discussion of a thematic model of teamwork that embraces formal, individual and organisational factors. Conclusions The need for effective teamwork in PHC is an issue receiving broad consensus; however, the process of teambuilding is often taken for granted in the PHC sector in Lithuania. This study suggests that both formal and individual behavioural factors should be targeted when aiming to strengthen PHC teams. Furthermore, this study underscores the need to provide explicit formal descriptions of the roles and responsibilities of PHC team members in Lithuania, which would include establishing clear professional boundaries. The training of team members is an essential component of the teambuilding process, but not sufficient by itself. PMID:23945286

[Survey on drug-related problems in Lithuania's pharmacies].

PubMed

Kubiliene, Loreta; Liukenskyte, Simona; Savickas, Arūnas; Jureniene, Kristina

2006-01-01

to survey the most common and the most important drug-related problems in Lithuania, to explore their solution and factors influencing it, to formulate recommendations for solving drug-related problems. Pharmacists from community pharmacies participated in a random survey. They filled in questionnaires about drug-related problems and their solutions. It was the first survey on drug-related problems ever carried out in Lithuania. For the first time, it was found out that in Lithuania pharmacists most commonly encountered drug-related problem--additional drug therapy (52.03% of respondents)--and most rarely encountered drug-related problem--dosage too high (3% of respondents). Pharmacists stated that all categories of drug-related problems were of equal importance. It was established that pharmacists commonly solved drug-related problems associated with noncompliance with instructions (72.5% of respondents) and rarely met the problem when improper drug was selected (39.56% of respondents). Patients taking prescription medicines commonly encounter additional drug therapy problem, and patients taking nonprescription medications commonly encounter problems related to noncompliance with instructions.

Systematic mapping review of the factors influencing physical activity and sedentary behaviour in ethnic minority groups in Europe: a DEDIPAC study.

PubMed

Langøien, Lars Jørun; Terragni, Laura; Rugseth, Gro; Nicolaou, Mary; Holdsworth, Michelle; Stronks, Karien; Lien, Nanna; Roos, Gun

2017-07-24

Physical activity and sedentary behaviour are associated with health and wellbeing. Studies indicate that ethnic minority groups are both less active and more sedentary than the majority population and that factors influencing these behaviours may differ. Mapping the factors influencing physical activity and sedentary behaviour among ethnic minority groups living in Europe can help to identify determinants of physical activity and sedentary behaviour, research gaps and guide future research. A systematic mapping review was conducted to map the factors associated with physical activity and sedentary behaviour among ethnic minority groups living in Europe (protocol PROSPERO ID = CRD42014014575). Six databases were searched for quantitative and qualitative research published between 1999 and 2014. In synthesizing the findings, all factors were sorted and structured into clusters following a data driven approach and concept mapping. Sixty-three articles were identified out of 7794 returned by the systematic search. These included 41 quantitative and 22 qualitative studies. Of these 58 focused on physical activity, 5 on both physical activity and sedentary behaviour and none focused on sedentary behaviour. The factors associated with physical activity and sedentary behaviour were grouped into eight clusters. Social & cultural environment (n = 55) and Psychosocial (39) were the clusters containing most factors, followed by Physical environment & accessibility (33), Migration context (15), Institutional environment (14), Social & material resources (12), Health and health communication (12), Political environment (3). An important finding was that cultural and religious issues, in particular those related to gender issues, were recurring factors across the clusters. Physical activity and sedentary behaviour among ethnic minority groups living in Europe are influenced by a wide variety of factors, especially informed by qualitative studies. More comparative studies are needed as well as inclusion of a wider spectrum of the diverse ethnic minority groups resettled in different European countries. Few studies have investigated factors influencing sedentary behaviour. It is important in the future to address specific factors influencing physical activity and sedentary behaviour among different ethnic minority groups in order to plan and implement effective interventions.

Pre-School Education in Lithuania: Historical Interpretation.

ERIC Educational Resources Information Center

Montvilaite, Sigita

During the 20th century, preschool education in Lithuania evolved within a context of a changing society, ideology, and politics, including the experience of national independence, two world wars, political exile and occupation, and regained independence. This paper demonstrates the connection between past and present preschool educational…

Internet Banking Adoption: Case of Lithuania and Latvia

ERIC Educational Resources Information Center

Gaile-Sarkane, Elina; Jureviciene, Diva; Skvarciany, Viktorija; Iljins, Juris

2017-01-01

The banking sector has developed and extended usage of different services at a distance using the internet in the last decade. Internet-based banking services dominate over other historically provided alternatives. This paper explores the adoption of internet banking in Lithuania and Latvia. Internet banking success model was developed based on…

DefenseLink Feature: Travels with Gates

Science.gov Websites

Robert M. Gates said. Story Gates Connects NATO Afghanistan Effort With Terror Threat in Europe MUNICH , Germany, Feb. 10, 2008 - The war on terror in Afghanistan is Europe's war, too, Defense Secretary Robert M ministers during meetings in Vilnius, Lithuania. Story Pakistan Understands Terror Danger VILNIUS, Lithuania

Lessons from Lithuania: A Pedagogical Approach in Teaching Improvisation

ERIC Educational Resources Information Center

Hedden, Debra

2017-01-01

The purpose of this study was to uncover the approach that a professor in Lithuania utilized in successfully teaching undergraduate music education majors how to improvise during a one-semester course. The research questions focused on the participant's philosophy of teaching and learning, his methods for motivating students, the learning…

Developing a systems-based framework of the factors influencing dietary and physical activity behaviours in ethnic minority populations living in Europe - a DEDIPAC study.

PubMed

Holdsworth, Michelle; Nicolaou, Mary; Langøien, Lars Jørun; Osei-Kwasi, Hibbah Araba; Chastin, Sebastien F M; Stok, F Marijn; Capranica, Laura; Lien, Nanna; Terragni, Laura; Monsivais, Pablo; Mazzocchi, Mario; Maes, Lea; Roos, Gun; Mejean, Caroline; Powell, Katie; Stronks, Karien

2017-11-07

Some ethnic minority populations have a higher risk of non-communicable diseases than the majority European population. Diet and physical activity behaviours contribute to this risk, shaped by a system of inter-related factors. This study mapped a systems-based framework of the factors influencing dietary and physical activity behaviours in ethnic minority populations living in Europe, to inform research prioritisation and intervention development. A concept mapping approach guided by systems thinking was used: i. Preparation (protocol and terminology); ii. Generating a list of factors influencing dietary and physical activity behaviours in ethnic minority populations living in Europe from evidence (systematic mapping reviews) and 'eminence' (89 participants from 24 academic disciplines via brainstorming, an international symposium and expert review) and; iii. Seeking consensus on structuring, rating and clustering factors, based on how they relate to each other; and iv. Interpreting/utilising the framework for research and interventions. Similar steps were undertaken for frameworks developed for the majority European population. Seven distinct clusters emerged for dietary behaviour (containing 85 factors) and 8 for physical activity behaviours (containing 183 factors). Four clusters were similar across behaviours: Social and cultural environment; Social and material resources; Psychosocial; and Migration context. Similar clusters of factors emerged in the frameworks for diet and physical activity behaviours of the majority European population, except for 'migration context'. The importance of factors across all clusters was acknowledged, but their relative importance differed for ethnic minority populations compared with the majority population. This systems-based framework integrates evidence from both expert opinion and published literature, to map the factors influencing dietary and physical activity behaviours in ethnic minority groups. Our findings illustrate that innovative research and complex interventions need to be developed that are sensitive to the needs of ethnic minority populations. A systems approach that encompasses the complexity of the inter-related factors that drive behaviours may inform a more holistic public health paradigm to more effectively reach ethnic minorities living in Europe, as well as the majority host population.

In comparative perspective: The effects of incarceration abroad on penal subjectivity among prisoners in Lithuania

PubMed Central

Slade, Gavin; Vaičiūnienė, Rūta

2017-01-01

This article looks at how global flows of people and policies affect penal subjectivity among prisoners in Lithuania. Those who had previously been incarcerated abroad perceive their punishment in Lithuania’s reforming penal system in comparative terms. We find that international prison experience may either diminish or increase the sense of the severity of the current punishment. Respondents often felt more comfortable in a familiar culture of punishment in Lithuania that emphasizes autonomy and communality. Moreover, internationalized prisoners perceive prison reform emulating West European models as a threat to this culture and are able to articulate comparative critiques of this reform and contest its effects. PMID:29568238

OECD Reviews of School Resources: Lithuania

ERIC Educational Resources Information Center

Shewbridge, Claire; Godfrey, Katrina; Hermann, Zoltán; Nusche, Deborah

2016-01-01

This report for Lithuania forms part of the OECD Review of Policies to Improve the Effectiveness of Resource Use in Schools. The purpose of the review is to explore how school resources can be governed, distributed, utilised and managed to improve the quality, equity and efficiency of school education. School resources are understood in a broad…

Arts and Cultural Education at School in Europe. Lithuania 2007/08

ERIC Educational Resources Information Center

Siaulytiene, Dalia

2008-01-01

Artistic education at general education schools in Lithuania is organised by teaching separate art subjects. Art education based on the integrated approach or project method may be organized at primary school, in grades one to four, according to the individual curriculum prepared by the teacher. Arts subjects included in Lithuanian arts curriculum…

Development of Indicators for Educational Planning: Brazil, Cambodia, Estonia, Gambia, Lithuania, Thailand.

ERIC Educational Resources Information Center

United Nations Educational, Scientific, and Cultural Organization, Paris (France). International Inst. for Educational Planning.

This publication presents the outcomes of a distance education course on development and dissemination of indicators used for educational planning. The course took place from November 2000 to February 2001 and was attended by representatives from the ministries of education of Brazil, Cambodia, Estonia, Gambia, Lithuania, and Thailand. The overall…

Music Performance Anxiety among Students of the Academy in Lithuania

ERIC Educational Resources Information Center

Paliaukiene, Vilma; Kazlauskas, Evaldas; Eimontas, Jonas; Skeryte-Kazlauskiene, Monika

2018-01-01

Music performance anxiety (MPA) affects amateurs, students and professional musicians. We aimed to analyse MPA among students of music performance in a higher education academy in Lithuania. A sample of 258 music performance arts students of the Lithuanian Music and Theatre Academy participated in this study. The Kenny Music Performance Anxiety…

Information Needs Research in Russia and Lithuania, 1965-2003

ERIC Educational Resources Information Center

Maceviciute, Elena

2006-01-01

Introduction: The invisibility of research on information needs from the East and Central Europe in the West suggested an exploration of the published research output from Lithuania and Russia from 1965 to 2003. Method: The data were collected from the abstracting journal Informatika-59. The publications were retrieved from Lithuanian and Russian…

E-Books in Academic Libraries: Results of a Survey Carried out in Sweden and Lithuania

ERIC Educational Resources Information Center

Maceviciute, Elena; Wilson, T. D.; Gudinavicius, Arunas; Šuminas, Andrius

2017-01-01

Introduction: This paper reports on a study of e-books issues in academic libraries in two European countries representative of small language markets--Sweden and Lithuania. Method: Questionnaire surveys, using the same instrument, were carried out in Swedish and Lithuanian academic libraries. Analysis: Quantitative analysis was performed using…

Investing in Youth: Lithuania

ERIC Educational Resources Information Center

OECD Publishing, 2016

2016-01-01

The series Investing in Youth builds on the expertise of the Organisation for Economic Cooperation and Development (OECD) on youth employment, social support and skills. It covers both OECD countries and countries in the process of accession to the OECD, as well as some emerging economies. The present report on Lithuania is the fourth of a new…

Legal assessment of current situation on orphan patients in Lithuania.

PubMed

Spokiene, Indre

2008-01-01

After Lithuania joined the European Union, the Regulation (EC) No. 141/2000 on orphan medicinal products and Commission Regulation (EC) No. 847/2000 came into force as part of national legislation. Member States must adopt specific measures to increase knowledge on rare diseases and to improve their detection, diagnosis, and treatment. The aim of this article was to present and to assess the current legal situation on orphan patients and their treatment in Lithuania, to identify legislation gaps, and to propose some ideas how to facilitate the solution of the existing problems in this field. For this purpose, European Union and Lithuanian legal documents on rare medicinal products are examined using a comparative method. With reference to inventory of Member States' incentives for rare diseases in national level, the most important issues, which orphan patients face to in Lithuania, are singled out. In Lithuania, the situation of orphan patients in terms of protection of patient rights is insufficiently determined. The access to effective health care services or approved therapies in some cases is restricted. Working relationships between genetic services and various clinical specialists as well as with those in primary care are not legally determined; the number of clinical trials aimed at orphan medicinal products is low. These results suggest a need for awareness raising among Lithuanian Government, health care specialists, patient organizations about the importance to improve practical implementation of European Union legislation and progressive experience of some European countries in this field.

The recent economic recession and self-rated health in Estonia, Lithuania and Finland: a comparative cross-sectional study in 2004-2010.

PubMed

Reile, Rainer; Helakorpi, Satu; Klumbiene, Jurate; Tekkel, Mare; Leinsalu, Mall

2014-11-01

The late-2000s financial crisis had a severe impact on the national economies on a global scale. In Europe, the Baltic countries were among those most affected with more than a 20% decrease in per capita gross domestic product in 2008-2009. In this study, we explored the effects of economic recession on self-rated health in Estonia and Lithuania using Finland, a neighbouring Nordic welfare state, as a point of reference. Nationally representative cross-sectional data for Estonia (n=10 966), Lithuania (n=7249) and Finland (n=11 602) for 2004-2010 were analysed for changes in age-standardised prevalence rates of less-than-good self-rated health and changes in health inequalities using logistic regression analysis. The prevalence of less-than-good self-rated health increased slightly (albeit not statistically significantly) in all countries during 2008-2010. This was in sharp contrast to the statistically significant decline in the prevalence of less-than-good health in 2004-2008 in Estonia and Lithuania. Health disparities were larger in Estonia and Lithuania when compared to Finland, but decreased in 2008-2010 (in men only). In Finland, both the prevalence of less-than-good health and health disparities remained fairly stable throughout the period. Despite the rapid economic downturn, the short-term health effects in Estonia and Lithuania did not differ from those in Finland, although the recession years marked the end of the previous positive trend in self-rated health. The reduction in health disparities during the recession indicates that different socioeconomic groups were affected disproportionately; however, the reasons for this require further research. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Minority Ethnic Students and Science Participation: A Qualitative Mapping of Achievement, Aspiration, Interest and Capital

ERIC Educational Resources Information Center

Wong, Billy

2016-01-01

In the UK, the "leaky pipeline" metaphor has been used to describe the relationship between ethnicity and science participation. Fewer minority ethnic students continue with science in post-compulsory education, and little is known about the ways in which they participate and identify with science, particularly in the secondary school…

Parenting Dimensions in Relation to Pre-Schoolers' Behaviour Problems in Latvia and Lithuania

ERIC Educational Resources Information Center

Sebre, Sandra B.; Jusiene, Roma; Dapkevice, Egle; Skreitule-Pikse, Inga; Bieliauskaite, Rasa

2015-01-01

The aim of the present study was to examine associations between parenting and child behaviour problems in two neighbouring countries with subtle, yet apparent cultural differences. Participants were mothers and fathers of preschool-age children from Latvia and Lithuania. Parents completed a measure of child-rearing attitudes and reported on their…

Economic, Educational and Cultural Predictors of Science Learning in Lithuania and Estonia

ERIC Educational Resources Information Center

Mikk, Jaan

2007-01-01

The aim of the research was to assess the economic, educational and cultural predictors of the TIMSS 2003 science test results in Lithuania and Estonia. The data for the research were received from the TIMSS 2003 User Guide for the International Database. The Spearman rank correlation coefficients, calculated on the students' level and the schools…

On Ideology, Language, and Identity: Language Politics in the Soviet and Post-Soviet Lithuania

ERIC Educational Resources Information Center

Balockaite, Rasa

2014-01-01

The paper illuminates links between state politics and language politics in Lithuania during different historical periods: (a) the thaw period, (b) the stagnation period, (c) the liberalization periods of Soviet socialism, and (d) the two post-Soviet decades characterized by both nationalism and liberalization. Based on analysis of the texts by…

First report of ‘Candidatus Phytoplasma asteris’ subgroup 16SrI-A associated with a disease of potato (Solanum tuberosum) in Lithuania

USDA-ARS?s Scientific Manuscript database

Symptoms of little leaf, witches’-broom, and abnormally small and deformed potatoes, suggestive of possible phytoplasmal infection, were observed in diseased potato (Solanum tuberosum var. Hannibal arba Kestrel) in the Vilnius region of Lithuania. DNA extracted from symptomatic leaves and shoots we...

Gap Year Students in Lithuania: The Value Orientations of Children from Wealthy Social Groups

ERIC Educational Resources Information Center

Leonavicius, Vylius; Ozolinciute, Egle

2015-01-01

The paper seeks to understand the trajectories of students who defer entry to university. The study was conducted in Lithuania, a former Soviet Union republic. The phenomenon of a "gap year" is usually associated with young people, who decide not to enter higher education schools immediately after receiving secondary education, instead…

Self-Regulated Learning Study Strategies and Academic Performance in Undergraduate Organic Chemistry: An Investigation Examining Ethnically Diverse Students

ERIC Educational Resources Information Center

Lopez, Enrique J.; Nandagopal, Kiruthiga; Shavelson, Richard J.; Szu, Evan; Penn, John

2013-01-01

This study sought to identify ethnically diverse students' study strategies in organic chemistry and their relationships to course outcomes. Study diaries, concept maps, and problem sets were used to assess study outcomes. Findings show that students engage in four commonly used reviewing-type strategies, regardless of ethnic group affiliation.…

"Lyderiu Laikas" (Time for Leaders): Lithuania's Response to Changing Leadership and Learning in Their Schools

ERIC Educational Resources Information Center

Jackson, Coleen; Blandford, Sonia; Pranckuniene, Egle; Vildziuniene, Marina

2011-01-01

This paper examines how the Ministry of Education in Lithuania has approached policy change to the leadership of their schools. The aim of the Time for Leaders Project and subsequent policy is to recapture the enthusiasm of teachers and school leaders that had been in evidence immediately after the country regaining independence in 1990. The Time…

Russian as a Commodity: Medical Tourism and the Healthcare Industry in Post-Soviet Lithuania

ERIC Educational Resources Information Center

Muth, Sebastian

2017-01-01

The focus of this paper is on Lithuania, where government policies continue to limit the use of Russian in education, the public space and the media, while the local economy has recognized proficiency in Russian as a commodity. This is particularly salient in the healthcare industry that grew significantly in the past years with patients from…

"Profits to the Danes, for Us--Hog Stench?" The Campaign against Danish Swine CAFOs in Rural Lithuania

ERIC Educational Resources Information Center

Juska, Arunas

2010-01-01

The paper analyzes a grass-roots campaign to limit the expansion of Danish-owned industrial hog operator Saerimner in Lithuania. The industrialization of livestock production as well as local responses to the restructuring of meat production are interpreted within the broader context of the incorporation of peripheral regions into global agro-food…

National Testing of Pupils in Europe: Objectives, Organisation and Use of Results. Lithuania 2009

ERIC Educational Resources Information Center

Bigeliene, Daiva; Gudynas, Pranas; Ranonyte, Asta; Uginciene, Egle

2009-01-01

The guiding principles of assessment policy and practice in Lithuania are described in the Law on Education (2003), General Curriculum and Educational Standards for Pre-school, Primary and Basic education (2003) and General Education Plans (2008-2009) as well as the special policy document on assessment called The Concept of Assessment of Pupils'…

Early Childhood Education and Care in Europe: Tackling Social and Cultural Inequalities. Lithuania

ERIC Educational Resources Information Center

Seibokiene, Grazina

2008-01-01

In Lithuania early childhood education and care embraces children of the age from one to seven and is an integrated part of the education system. According to Lithuanian education classification, it belongs to the zero level of education. Though defined as pre-school education yet this stage is composed of two parts--pre-school education of…

Chemical Polymorphism of Essential Oils of Artemisia vulgaris Growing Wild in Lithuania.

PubMed

Judzentiene, Asta; Budiene, Jurga

2018-02-01

Compositional variability of mugwort (Artemisia vulgaris L.) essential oils has been investigated in the study. Plant material (over ground parts at full flowering stage) was collected from forty-four wild populations in Lithuania. The oils from aerial parts were obtained by hydrodistillation and analyzed by GC(FID) and GC/MS. In total, up to 111 components were determined in the oils. As the major constituents were found: sabinene, 1,8-cineole, artemisia ketone, both thujone isomers, camphor, cis-chrysanthenyl acetate, davanone and davanone B. The compositional data were subjected to statistical analysis. The application of PCA (Principal Component Analysis) and AHC (Agglomerative Hierarchical Clustering) allowed grouping the oils into six clusters. AHC permitted to distinguish an artemisia ketone chemotype, which, to the best of our knowledge, is very scarce. Additionally, two rare cis-chrysanthenyl acetate and sabinene oil types were determined for the plants growing in Lithuania. Besides, davanone was found for the first time as a principal component in mugwort oils. The performed study revealed significant chemical polymorphism of essential oils in mugwort plants native to Lithuania; it has expanded our chemotaxonomic knowledge both of A. vulgaris species and Artemisia genus. © 2018 Wiley-VHCA AG, Zurich, Switzerland.

Overturn of the proposed alcohol advertising ban in Lithuania.

PubMed

Paukštė, Ernesta; Liutkutė, Vaida; Stelemėkas, Mindaugas; Goštautaitė Midttun, Nijolė; Veryga, Aurelijus

2014-05-01

In response to the dramatic increase in alcohol-related problems in Lithuania, policy measures, including alcohol advertising and availability restrictions combined with taxation increase, were implemented in 2007-08. Simultaneously, a full alcohol advertising ban was adopted to take effect from 1 January 2012. Therefore, the alcohol industry responded with extensive lobbying aiming to revoke this ban, and ultimately they succeeded at the end of December 2011. To document and analyse actions of stakeholders and events during the alcohol advertising ban cancellation process in Lithuania. Policy analysis includes a development of event time-line, description of key stakeholders' actions and a review of policy context. The alcohol industry in Lithuania used similar tactics as the tobacco industry globally, such as creating strong and diverse opposing groups. The industry successfully exerted pressure to change alcohol control legislation, while non-governmental organizations had the important role of a watchdog, blunting industry's efforts. Unequal power distribution made it difficult to withstand combined local and international lobbying to cancel the ban. Given the global nature of the alcohol industry, there is a need for international regulation to limit the influence of vested interests on national lawmaking. © 2014 Society for the Study of Addiction.

RES-E Support Policies In The Baltic States: Development Aspect (Part I)

NASA Astrophysics Data System (ADS)

Bobinaite, V.; Priedite, I.

2015-02-01

Despite quite similar conditions (natural resources) for electricity production from renewable energy sources (RES-E) in three Baltic States (Estonia, Latvia and Lithuania), significant differences exist in these countries as to the RES-E production volume. In Latvia this volume is the highest, while in Estonia and Lithuania it is half as high. One of the factors that determine the RES-E production volumes is support policies, which in the Baltic States are different. The main objective of this work was to analyze and compare these support policies. The results have shown that for rapid RES-E development the most effective policy is to be market-oriented (as in Estonia), whereas for more stable development such policy should be producer-oriented (as in Lithuania).

The impact of Nordic adult education ideas on the development of a democratic society in Lithuania

NASA Astrophysics Data System (ADS)

Teresevičienė, Margarita; Trepulė, Elena; Trečiokienė, Edita

2017-02-01

This article analyses the role of the cooperation with and the influence of the Nordic countries on the development of a democratic society in Lithuania through adult education since the reinstatement of its independence from Soviet regime in March 1990 to the present. The authors focus on three main areas: (1) the training of Lithuanian adult educators; (2) the establishment and development of NGOs; and (3) the implications for a Lithuanian policy of adult education. Within the framework of Nordic-Baltic cooperation established among five Nordic and three Baltic countries (NB8) in 1992, Lithuanian adult educators seized the opportunity to visit Scandinavian institutions and projects. Experiencing Nordic adult education ideas has resulted in a marked shift in Lithuanian adult educators' values, methodology and careers; and in the establishment of a series of very influential umbrella associations as well as hundreds of NGOs in Lithuania which work with adults and support functioning democratic values in society. This shift is related to the civic responsibility and active participation growing out of the bottom-up approaches of group work, cooperation, discussions and learning circles which are so inherent in the Nordic tradition of adult education. The internalisation of new democratic values was more complicated than expected for many Lithuanian politicians, adult educators and NGO leaders in terms of how political decisions were perceived and implemented. Furthermore, the influence of the Nordic-Baltic cooperation in adult education may also be traced in adult education policy implications in Lithuania. Some changes in the policies of contemporary Lithuania have not been successful and even failed to promote a democratic society.

Infant mortality gap in the Baltic region - Latvia, Estonia, and Lithuania - in relation to macroeconomic factors in 1996-2010.

PubMed

Ebela, Inguna; Zile, Irisa; Ebela, Danute Razuka; Rozenfelde, Ingrida Rumba

2013-01-01

BACKGROUND AND OBJECTIVE. A constant gap has appeared in infant mortality among the 3 Baltic States - Latvia, Estonia, and Lithuania - since the restoration of independence in 1991. The aim of the study was to compare infant mortality rates in all the 3 Baltic countries and examine some of the macro- and socioeconomic factors associated with infant mortality. MATERIAL AND METHODS. The data were obtained from international databases, such as World Health Organization and EUROSTAT, and the national statistical databases of the Baltic States. The time series data sets (1996-2010) were used in the regression and correlation analysis. RESULTS. In all the 3 Baltic States, a strong and significant correlation was found: Latvia (r=-0.81, P<0.01), Lithuania (r=-0.93, P<0.01), and Estonia (r=-0.91, P<0.01). There was also a correlation between infant mortality and healthcare expenditure in local currency per capita: Latvia (r=-0.81, P<0.01); Lithuania (r=-0.90, P<0.01) and Estonia (r=-0.88, P<0.01). In Latvia (r=0.87, P<0.01) and Estonia (r=0.70; P<0.01), a significant correlation between infant mortality and unemployment levels was observed from 1996 to 2008, whereas the statistical significance disappeared in the period from 1996 to 2010. In Lithuania, the relationship was not significant. CONCLUSIONS. Higher infant mortality rates and a less stable decreasing tendency in Latvia are apparently explained by less successful adaptation to a new political and economic situation and limited skills in adjusting the healthcare system to the reality of life.

Curriculum Change and Social Inclusion: Perspectives from the Baltic and Scandinavian Countries. Final Report of the Regional Seminar (Vilnius, Lithuania, December 5-8, 2001).

ERIC Educational Resources Information Center

Tawil, Sobhi, Ed.

The main objectives of a Vilnius, Lithuania, seminar were to share experiences in curriculum reform to promote life skills for social inclusion. This was to be achieved through an exchange on principles, approaches and methodologies that inform processes of curriculum reform in life skills education. Most of the participants were senior education…

JPRS Report, Soviet Union, Political Affairs.

DTIC Science & Technology

1989-09-07

Rehabilitates Cardinal Vaivods [SOVETSKAYA LATVIYA, 15 Jun 89] 35 Church Built By Boris Godunov Conducts Religious Services [I. Serebryakov...from 1920 through 1940; —the history of the LSDRP [Latvian Social-Democratic Workers Party] from 1918 ; —the evaluation of the 23 August 1939...parallels with the 1918 situation in Lithuania in our arguments are incorrect. Let us recall the fact alone that Lithuania at that time used 400 tons of

Renal Anemia Control in Lithuania: Influence of Local Conditions and Local Guidelines

PubMed Central

Kuzminskis, Vytautas; Vaiciuniene, Ruta; Stankuviene, Asta; Bumblyte, Inga Arune

2013-01-01

Erythropoietin stimulating agents had a long haul in Lithuania—we had no epoetin till 1994 and there was no intravenous iron in 2001–2004. The aim of this study was to assess the changes of renal anemia control in hemodialysis patients from early independence of Lithuania till nowadays and to evaluate the link of anemia with hospitalization rates and survival and hemoglobin variability in association with mortality. In December of each year since 1996 all hemodialysis centers have been visited and data has been collected using special questionnaires. The history of renal anemia control in Lithuania was complicated; however, a significant improvement was achieved: 54.7% of hemodialysis patients reached the target hemoglobin; all patients have a possibility of treatment with epoetin and intravenous iron. The involuntary experiment with an intravenous iron occurred in Lithuania because of economic reasons and confirmed the significant role of intravenous iron in the management of renal anemia. Hemoglobin below 100 g/L was associated with a 2.5-fold increase in relative risk of death and 1.7-fold increase in relative risk of hospitalization in Lithuanian hemodialysis patients. Although hemoglobin variability was common in Lithuanian hemodialysis patients, we did not find the association between hemoglobin variability and all-cause mortality in our study. PMID:24367239

Liquid drugs and high dead space syringes may keep HIV and HCV prevalence high - a comparison of Hungary and Lithuania.

PubMed

Gyarmathy, V Anna; Neaigus, Alan; Li, Nan; Ujhelyi, Eszter; Caplinskiene, Irma; Caplinskas, Saulius; Latkin, Carl A

2010-01-01

Despitevery similar political, drug policy and HIV prevention backgrounds, HIV and HCV prevalence is considerably different in Hungary (low HIV and moderate HCV prevalence) and Lithuania (high HCV and moderate HIV prevalence). Wecompared the drug use profile of Hungarian (n = 215) and Lithuanian (n = 300) injecting drug users (IDUs). Overall, compared with IDUs in Hungary, IDUs in Lithuania often injected opiates purchased in liquid form ('shirka'), used and shared 2-piece syringes (vs. 1-piece syringes) disproportionately more often, were less likely to acquire their syringes from legal sources and had significantly more experience with injected and less experience with non-injected drugs. It may not be liquid drugs per se that contribute to a higher prevalence of HCV and/or HIV, but it is probably factors associated with the injecting of liquid drugs, such as the wide-spread use and sharing of potentially contaminated 2-piece syringes acquired often from non-legal sources, and syringe-mediated drug sharing with 2-piece syringes. Scaling up substitution therapy, especially heroin replacement, combined with reducing the supply of liquid drugs may decrease the prevalence of high-risk injecting behaviours related to the injecting of liquid drugs and drug injecting-related infections among IDUs in Lithuania. Copyright © 2010 S. Karger AG, Basel.

Geosites of Lithuania as an environment for dwelling of specific biota: geo- and biodiversity interactions

NASA Astrophysics Data System (ADS)

Skridlaite, Grazina; Motiejunaite, Jurga; Jukoniene, Ilona; Prigodina Lukosiene, Ingrida

2016-04-01

Surface of Lithuania and surrounding countries is sculptured by five glaciations, which left behind morainic tills and melt water deposits, modified by erosion and later used for agriculture or overgrown by wild meadows or forests. The glaciations also left numerous erratic boulders and boulder fields that are declared as natural monuments in Lithuania and surrounding countries. Tens of single boulders and boulder fields are included into the Geosites database at the Lithuanian Geological Survey. Though sparse, but of high scientific value, Devonian, Permian, Triassic and Jurassic outcrops and quarries of Lithuania are variably protected. Quaternary scientists attempted to use single erratic boulders, their fields and abundances in tills to imply glacier dynamics. Some erratics came from known localities in Scandinavia and are called indicator boulders because they show the source and directions of ice sheet movements. Huge single boulders (e.g. 7 m long and 6 m high Puntukas, Anyksciai Regional Park) and wild boulder fields are natural monuments and attractive sites for visitors. Outcrops and quarries of Devonian dolomites and gypsium, Permian limestones and Jurassic sandstones widely used for a scientific research are parts of the protected geo-diversity in the Venta and Birzai regional parks, N and NW Lithuania. On the other hand, a large part of the c. 700 species of lichenized and allied fungi and of c. 500 bryophytes known in Lithuania are confined to natural or semi-natural (quarries) rocky habitats. Eight rock-dwelling lichen and nine bryophyte species are included in the Lithuanian Red Data Book, some of them are known from 1-2 localities or are thought to be extinct now. Besides, the recent investigations of dolomite quarries revealed them to be habitats for 7 bryophyte, 8 lichenized and lichenicolous species, previously unknown for Lithuania. One new lichenicolous species was discovered (Khodosovtsev et al., 2012). Some of the newfinds are rare or absent also in the neighbouring countries. In general, protection of geo-diversity coincides well with protection of narrowly specialized cryptogams, e.g. overgrowing of boulder fields with tall herbs and shrubs also has adversary effect on rock-dwelling lichens. Shading of Devonian outcrops and quarries by trees and shrubs may obscure rocky surfaces and destroy lichens, but favour an establishment of sciophyllous bryophytes. No doubt that cleaning of surfaces of single boulders that are well-known nature monuments prevents an establishment and growth of lichens and bryophytes. However, most of the geological monuments which are subjected to cleaning are situated in localities under strong anthropogenic impact and therefore not suitable for settlement of the rare and protected species. Though conservation conflicts arise even when protecting different species of biota, not to mention conservation of bio- versus geo-diversity, most of the conservation measures for the geoheritage in Lithuania are also suitable for rock-inhabiting lichens and bryophytes. Protection status and measures should be negotiated by bio-and geoscientists, and legislation for bio- and geo-diversity protection should be improved. Khodosovtsev, A., Vondrák, J., Naumovich, A., Kocourková, J., Vondráková, O., Motiejūnaitė, J., 2012. Nova Hedwigia, 95(1-2): 211-220.

Systematic mapping review of the factors influencing dietary behaviour in ethnic minority groups living in Europe: a DEDIPAC study.

PubMed

Osei-Kwasi, Hibbah Araba; Nicolaou, Mary; Powell, Katie; Terragni, Laura; Maes, Lea; Stronks, Karien; Lien, Nanna; Holdsworth, Michelle

2016-07-28

Europe has a growing population of ethnic minority groups whose dietary behaviours are potentially of public health concern. To promote healthier diets, the factors driving dietary behaviours need to be understood. This review mapped the broad range of factors influencing dietary behaviour among ethnic minority groups living in Europe, in order to identify research gaps in the literature to guide future research. A systematic mapping review was conducted (protocol registered with PROSPERO 2014: CRD42014013549). Nine databases were searched for quantitative and qualitative primary research published between 1999 and 2014. Ethnic minority groups were defined as immigrants/populations of immigrant background from low and middle income countries, population groups from former Eastern Bloc countries and minority indigenous populations. In synthesizing the findings, all factors were sorted and structured into emerging clusters according to how they were seen to relate to each other. Thirty-seven of 2965 studies met the inclusion criteria (n = 18 quantitative; n = 19 qualitative). Most studies were conducted in Northern Europe and were limited to specific European countries, and focused on a selected number of ethnic minority groups, predominantly among populations of South Asian origin. The 63 factors influencing dietary behaviour that emerged were sorted into seven clusters: social and cultural environment (16 factors), food beliefs and perceptions (11 factors), psychosocial (9 factors), social and material resources (5 factors), accessibility of food (10 factors), migration context (7 factors), and the body (5 factors). This review identified a broad range of factors and clusters influencing dietary behaviour among ethnic minority groups. Gaps in the literature identified a need for researchers to explore the underlying mechanisms that shape dietary behaviours, which can be gleaned from more holistic, systems-based studies exploring relationships between factors and clusters. The dominance of studies exploring 'differences' between ethnic minority groups and the majority population in terms of the socio-cultural environment and food beliefs suggests a need for research exploring 'similarities'. The evidence from this review will feed into developing a framework for the study of factors influencing dietary behaviours in ethnic minority groups in Europe.

The Al-Hiraak Movement in Yemen: A Study of the Implications of Federalization on a Secession Movement

DTIC Science & Technology

2014-12-04

backing the established 19 Allen Buchanan, Secession: The Morality of Political Divorce from Fort Sumter to Lithuania and Quebec (Boulder: Westview...behavior as being a result of either deprivation or social marginalization. Deprivation is generally defined as poverty or the denial of political...South Arabia. London: I.B. Tauris, 2011. Buchanan, Allen. Secession: The Morality of Political Divorce from Fort Sumter to Lithuania and Quebec

Trends and social differences in alcohol consumption during the postcommunist transition in Lithuania.

PubMed

Klumbiene, Jurate; Kalasauskas, Darius; Petkeviciene, Janina; Veryga, Aurelijus; Sakyte, Edita

2012-01-01

The aim of the study was to evaluate the trends and social differences in consumption of various types of alcoholic beverages in Lithuania over the postcommunist transition period (1994-2010). The data were obtained from nine nationally representative postal surveys of Lithuanian population aged 20-64 conducted every second year (n = 17154). Prevalence of regular (at least once a week) consumption of beer, wine, or strong alcoholic beverages and the amount of alcohol consumed per week were examined. Regular beer drinking as well as the amounts consumed increased considerably in both genders. The increase in regular consumption of strong alcohol was found among women. Sociodemographic patterning of regular alcohol drinking was more evident in women than in men. In women, young age and high education were associated with frequent regular drinking of wine and beer. Social differences in regular alcohol drinking should be considered in further development of national alcohol control policy in Lithuania.

Space plant biology research in Lithuania.

PubMed

Ričkienė, Aurika

2012-09-01

In 1957, the Soviet Union launched the first artificial Earth satellite, initiating its space exploration programs. Throughout the rest of the twentieth century, the development of these space programs received special attention from Soviet Union authorities. Scientists from the former Soviet Republics, including Lithuania, participated in these programs. From 1971 to 1990, Lithuanians designed more than 20 experiments on higher plant species during space flight. Some of these experiments had never before been attempted and, therefore, made scientific history. However, the formation and development of space plant biology research in Lithuania or its origins, context of formation, and placement in a worldwide context have not been explored from a historical standpoint. By investigating these topics, this paper seeks to construct an image of the development of a very specific field of science in a small former Soviet republic. Copyright © 2012 Elsevier Ltd. All rights reserved.

Homicide Rates in Lithuania.

PubMed

Chmieliauskas, Sigitas; Laima, Sigitas; Andriuskeviciute, Gerda; Jurolaic, Eleonora; Jasulaitis, Algimantas

2018-05-01

Homicide rate in Lithuania between 2004 and 2013 decreased and reached an average of 6.7 per 100,000 people in 2013. The data regarding forensic autopsies of intentional homicide victims were obtained from the State Forensic Medicine Service. Spearman's correlation test was used to assess trends in the homicide rates. A significant correlation was observed between homicide distribution and the following variables: Lithuania's gross domestic product (r = -0.85, p = 0.003), the number of alcohol intoxication cases of victims (r = 0.97, p < 0.05). After regression model adjustments, these variables remained significantly associated with the homicide distribution (p < 0.05). 73% of victims were men, with a mean age of 45.5 ± 15. Alcohol intoxication was present in 58% of victims. 66% of homicides were carried out indoors, 57% in urban area. The presented findings help decide which prevention programs may be the most effective in homicide rate reduction. © 2017 American Academy of Forensic Sciences.

Review of State Legislative Approaches to Eliminating Racial and Ethnic Health Disparities, 2002–2011

PubMed Central

Pollack, Keshia; Rutkow, Lainie

2015-01-01

We conducted a legal mapping study of state bills related to racial/ethnic health disparities in all 50 states between 2002 and 2011. Forty-five states introduced at least 1 bill that specifically targeted racial/ethnic health disparities; we analyzed 607 total bills. Of these 607 bills, 330 were passed into law (54.4%). These bills approached eliminating racial/ethnic health disparities by developing governmental infrastructure, providing appropriations, and focusing on specific diseases and data collection. In addition, states tackled emerging topics that were previously lacking laws, particularly Hispanic health. Legislation is an important policy tool for states to advance the elimination of racial/ethnic health disparities. PMID:25905834

Study on Customer Satisfaction with Facilities Management Services in Lithuania

NASA Astrophysics Data System (ADS)

Lepkova, Natalija; Žūkaitė-Jefimovienė, Giedrė

2012-12-01

The article introduces the concept and content of facilities management (FM) services. The paper presents the concept of customer satisfaction and discusses the key factors which influence the opinions of customers and their satisfaction or dissatisfaction with the services provided. The article presents two studies: a brief survey of several FM service providers and a survey of customer satisfaction with FM services in Lithuania. The conclusions are given at the end of the article.

Epidemiology of paediatric burns in Lithuania: focus on a vulnerable population exposed to the risk of scalds at home without hot tap water supply.

PubMed

Kubilius, Darius; Smailytė, Giedrė; Rimdeikienė, Inesa; Malcius, Dalius; Kaikaris, Vygintas; Rimdeika, Rytis

2014-05-01

To describe the epidemiology of paediatric burns in Lithuania, identify the trends of burn occurrence, the vulnerable population and aetiology. This study was based on all inclusive national information obtained from the National Health Insurance database for the period of 2001-2010. Information on the burns aetiology was collected in the Hospital of Lithuanian University of Heath Sciences Kauno Klinikos. 7146 children in the age group of 0-14 were hospitalized in Lithuania and constituted 44% of all admissions due to burns. The incidence among boys was 149.8 and among girls 99.9 per 100,000. The highest risk of burns was observed from 11 to 15 months of age. Scalding in 0-1 years age group composed 96% of all burns in this age group. Children younger than 2 years of age are a vulnerable population of burns in Lithuania. Scalding was main cause of their burns. The aetiological subgroups of scalding were scalding with hot drinks/food and scalding with hot water meant for household. The major part of scalding with hot drinks was due to scalding with parents' drinks. Scalding with hot water meant for household is associated with the lack of hot water supply. Copyright © 2013 Elsevier Ltd and ISBI. All rights reserved.

The Palaeoproterozoic accretionary crustal growth: implications from new age data on the crystalline basement in Lithuania, NW Belarus and N Poland (the East European Craton)

NASA Astrophysics Data System (ADS)

Skridlaite, G.; Bogdanova, S.; Taran, L.; Wiszniewska, J.

2012-04-01

A southwestward younging of Palaeoproterozoic terranes in the crystalline basement in the western part of the East European Craton has been recently suggested by numerous isotopic datings (TIMS, SIMS zircon, EPMA monazite and 40Ar/39Ar). Along with geochemical and geophysical data this allows to decipher a multistage accretionary history. In the east, the Belarus-Podlasie Granulite belt (BPG) is dominated by 1.88 Ga dioritic-granodioritic (calc-alkaline) magmatism in Belarus (Claesson et al., 2001). Remnants of c. 1.89 Ga metadiorites, c. 1.90 Ga magmatic zircon cores in c. 1.80 Ga granites (Vejelyte, 2011) in S and E Lithuania and 1.88 Ga metagranodiorites in E Poland (Radzyn area) confirm the c. 1.90 Ga accretion-related magmatism in the BPG and the East Lithuanian domain. Together with the coeval juvenile granitoids in the adjacent Okolovo terrane this indicates the formation of the Lithuanian-Belarus composite terrane at 1.90-1.88 Ga. At c. 1.86-1.84 Ga, abundant gabbro-diorite-granodiorite-granite intrusions were emplaced further southwest in Lithuania, NW Belarus and N Poland. In Lithuana, within the Polish-Lithuanian terrane the TTG suite of deformed and metamorphosed in amphibolite facies calc-alkaline tonalitic, quartz dioritic and dioritic rocks is characteristic for the Randamonys massif. The strongly deformed granitoids in the adjacent NW Belarus, mafic granulites and gneissic granites of igneous origin in central Lithuania, garnet-cordierite bearing granites further north display similar c. 1.84 Ga magmatic age (Motuza et al., 2008). This shows that various tectonic settings including island and continental magmatic arcs were possible. They were accreted to the Lithuanian-Belarus terrane sometime at 1.84-1.81 Ga while voluminous charnockitic magmatism took place in W Lithuania (e.g. Claesson et al., 2001; Vejelyte, 2011). A chain of younger c. 1.83 Ga volcanic arcs was developed in W and S Lithuania and N Poland (Wiszniewska et al., 2005). The widespread c. 1.80-1.76 Ga metamorphism and tholeiitic magmatism related to post-collisional extension constrain the maximum age of the final accretion of the terranes. It is evidenced by numerous 1.80-1.79 Ga gabbro-noritic, dioritic and granitic intrusions in NE Poland and elsewhere in Lithuania and Belarus (Claesson, 2001; Vejelyte, 2011). The later reworking at c. 1.70-1.45 Ga and c. 1.60-1.45 Ga AMCG magmatism affected the already accreted craton. Evolutionary, a 1.90-1.87 Ga continental margin was established in present-day E Lithuania and NW Belarus, while younger volcanic arcs were still forming to the west and south at 1.86-1.84 Ga. They had been subsequently accreted to the c. 1.89 Ga continental margin in the time span of 1.84-1.80 Ga, and a new continental margin emerged. After the youngest c. 1.83-1.80 Ga island arcs were docked, the ocean was closed and the crust was finally cratonized. The younger 1.70-1.45 Ga events were intracratonic reflections of active geological processes further west. This is a contribution to the project "Precambrian rock provinces and active tectonic boundaries across the Baltic Sea and in adjacent areas" of the Visby Programme (the Swedish Institute), Lithuanian Science Council grant MIP-034/2011 and SYNTHESYS project SE-TAF-1535

[Survival of hemodialysis patients in Lithuania (data from all hemodialysis centers in the 1998-2005 cohort)].

PubMed

Stankuviene, Asta; Bumblyte, Inga Arūne; Kuzminskis, Vytautas; Ziginskiene, Edita; Balciuviene, Vilma

2007-01-01

There is no any official renal registry in Lithuania, so in order to know the exact demographic statistics of patients on hemodialysis, we started to collect data since 1996. The aim of the study was to estimate the survival rate of hemodialysis patients and its dynamics, to compare survival in different groups of sex, age, primary renal disease, and to compare to survival of dialysis patients in Europe. We analyzed the data of all patients who started hemodialysis in Lithuania between January 1, 1998, and December 31, 2005. The information was obtained from medical documentation. The total survival rate was estimated using the Kaplan-Maier method. During the study period, 2418 patients started hemodialysis (51.7% of males, 48.3% of females). Their mean age at the beginning of treatment was 56.19+/-16.12 years. Death occurred in 792 patients. The main cause of death was cardiovascular events, accounting for 32.3%. The total survival rate of hemodialysis patients in Lithuania at 1 year was 79.97%; at 2 years, 69.18%; at 5 years, 49.97%; at 7 years, 38.3%. Males lived longer than females (log rank P<0.05), but the mean age of females was greater, and survival rate adjusted for age did not differ between the groups. The highest survival rate was in the youngest group (0-19 years old), the lowest - in patients older than 75 years. Diabetic patients lived shorter than nondiabetic patients (log rank P<0.00001). Although patients who start hemodialysis have become older and their survival has been improving, in the 1998-2002 cohort survival was lower as compared to overall survival of patients on dialysis in European countries participating in ERA-EDTA registry. Survival of hemodialysis patients in Lithuania in the 1998-2005 cohort depended on age and primary renal disease and despite aging of population on hemodialysis has been improving.

[Development of hemodialysis service in Lithuania during (1996-2003)].

PubMed

Ziginskiene, Edita; Kuzminskis, Vytautas; Stankuviene, Asta; Santockiene, Lina; Kybartiene, Sondra; Labutiene, Vilma; Makaraite, Alanta; Vainauskas, Vaclovas; Macius, Kazimieras; Sakalauskiene, Marija; Sirevicius, Virgilijus; Urbanaviciene, Jūrate

2005-01-01

The aim of our study was to evaluate the changes of hemodialysis (HD) service and main demographic characteristics of HD patients in Lithuania during seven years period. From 1996 to 2003 we visited annually all HD centers in Lithuania and collected data about all HD patients. There was a sharp increase in the number of HD centers (from 17 to 37), HD stations (from 25 p. m. p. (per million population) to 87 p.m.p.; p<0.001), HD patients (from 60 p.m.p. to 264 p.m.p.; p<0.001) and incidence of new HD patients (from 54.3 p.m.p. to 92 p.m.p.; p<0.01). In 1996 all 17 HD centers in Lithuania were public. Private HD centers appeared in 1998 and reached 43.2% of all HD centers (n=16) in 2003. 44.8% of HD patients were dialyzed in private HD centers. The mean age of HD patients increased from 47.2+/-16.1 years in 1996 to 57.5+/-14.9 years in 2003 (p<0.001). HD population became older. The percentage of patients over 60 years old increased from 22.8% to 49.7% (p<0.001) and over 70 years old--from 54% to 21.9% (p<0.001). The main underlying disease of end-stage renal disease was chronic glomerulonephritis but its rate had decreased from 54.5% in 1996 to 26.5% in 2003 (p<0.001). During this period there was a statistically significant increase in the incidence of end-stage renal disease due to diabetics (from 7.1% to 18.0%; p<0.01), hypertensive nephropathy (from 3.1% to 9.4%; p<0.05), and chronic pyelonephritis (from 11.2% to 18.6%; p<0.01). In summary during the last seven years HD service in Lithuania expanded significantly, and rapid development of private HD was observed. The number of HD patients was rising continuously with predominance of diabetic, hypertensive and elderly patients.

Identification and genetic characterization of Sarcocystis arctica and Sarcocystis lutrae in red foxes (Vulpes vulpes) from Baltic States and Spain.

PubMed

Kirillova, Viktorija; Prakas, Petras; Calero-Bernal, Rafael; Gavarāne, Inese; Fernández-García, José Luis; Martínez-González, Manuel; Rudaitytė-Lukošienė, Eglė; Martínez-Estéllez, Miguel Ángel Habela; Butkauskas, Dalius; Kirjušina, Muza

2018-03-12

Typically, carnivores serve as definitive hosts for Sarcocystis spp. parasites; currently, their role as intermediate hosts is being elucidated. The present study aimed to identify and molecularly characterize Sarcocystis cysts detected in striated muscle of red foxes from different populations in Latvia, Lithuania and Spain. Muscle samples from 411 red foxes (Vulpes vulpes) and 269 racoon dogs (Nyctereutes procyonoides) from Latvia, 41 red foxes from Lithuania and 22 red foxes from Spain were examined for the presence of Sarcocystis sarcocysts by light microscopy (LM). Sarcocystis spp. were identified by transmission electron microscopy (TEM) and molecular biology techniques. Sarcocystis cysts were detected in 11/411 (2.7%) Latvian, 3/41 (7.3%) Lithuanian, and 6/22 (27.3%) Spanish red foxes, however, cysts were not observed in the muscles of racoon dogs. Based on LM, TEM, 18S rDNA, 28S rDNA, ITS1, cox1 and rpoB sequences, Sarcocystis arctica and Sarcocystis lutrae cysts were identified in red fox muscles from Latvia and Lithuania, whereas only S. arctica was detected in Spain. The 18S rDNA, 28S rDNA and ITS1 sequences from the 21 isolates of S. arctica from Latvia, Lithuania and Spain were identical. By contrast, two and four haplotypes were determined based on mtDNA cox1 and apicoplast rpoB sequences, respectively. Polymorphisms were not detected between the two isolates of S. lutrae from Latvia and Lithuania. Based on phylogenetic results, S. arctica and S. lutrae were most closely related to Sarcocystis spp. using predatory mammals as intermediate hosts and to Sarcocystis species with a bird-bird life-cycle. Based on current knowledge, the red fox and Arctic fox (Vulpes lagopus) could act as intermediate host for the same two Sarcocystis species. Molecular results suggest the existence of two genetic lineages of S. arctica, and such divergence relies on its geographical distribution but not on their intermediate host species.

The Influence of Race-Ethnicity and Physical Activity Levels on Elementary School Achievement

ERIC Educational Resources Information Center

Caldas, Stephen J.; Reilly, Monique S.

2018-01-01

The authors used structural equation modeling to map the relationships between student race-ethnicity via the mediating variable physical activity on English language arts (ELA) and mathematics achievement among 964 fourth- and fifth-grade students. The students attended a New York City Metropolitan area school district and completed the Physical…

Teaching ethics in a Masters Program in Public Health in Lithuania

PubMed Central

Jakusovaite, Irayda; Bankauskaite, Vaida

2007-01-01

This article aims to present 10 years of experience of teaching ethics in a Masters Program in Public Health in Lithuania, and to discuss the content, skills, teaching approach and tools of this programme. In addition, the article analyses the links between ethics and law, identifies the challenges of the teaching process and suggests future teaching strategies. The important role of teaching ethics in countries that are in transition owing to a radically changing value system is emphasised. PMID:17601872

[WILD MAMMALS OF THE GRAND DUCHY OF LITHUANIA IN THE WORKS OF JEAN-EMMANUEL GILIBERT].

PubMed

Samojlik, Tomasz; Daszkiewicz, Piotr

2015-01-01

Among the many topics of lively scientific work that Jean Emmanuel Gilibert (1741-1814) conducted in Grodno and Vilnius, an important place is occupied by his observations of wild mammals. Royal patronage and care from Antoni Tyzenhauz, Treasurer of the Grand Duchy of Lithuania and the governor of Grodno, allowed Gilibert to keep and observe wild fauna captured by royal services in royal forests, including Białowieża Primeval Forest. Such was an origin of a female bison kept by Gilibert in Grodno. Its description, published in Indagatores naturae in Lithuania (Vilnius 1781) for decades became the primary source of information about the behaviour, food preferences and the anatomy of European bison. European science has just begun to take interest in European bison, therefore Gilibert's account entered scientific circulation by way of French natural history encyclopaedias (mainly Georges Buffon's Histoire naturelle) and works by Georges Cuvier or Étienne Geoffroy Saint-Hilaire. Apart from the description of European bison, Gilibert left an entire series of observations of wild mammals inhabiting the forests of the Grand Duchy of Lithuania. His accounts of moose were important in building a knowledge base for this species. In the first half of the 18th century, moose was known mainly from fantastic descriptions in Renaissance works and from prescriptions devoted to using moose hoof as the epilepsy treatment. Gilibert's observations helped to overthrow such superstitions. Similarly, Gilibert's first-hand information verified the widespread legends concerning brown bear (e.g. the belief that white bears, belonging to other species than polar bears, occur in Lithuania) . List of species kept and thoroughly watched by the scholar is much longer and includes lynx, wolf (and hybrids of wolves and dogs), beaver, badger, fox, hedgehog, and even white mouse. Also his comments on the species of mammals then absent in Lithuania but known either from farming or from the fur trade (wolverine, bobak marmot or steppe polecat). Also in these cases, Gilibert's descriptions were often the first reliable information that entered the circulation in European science. His accounts were not free of errors and mistakes--but they resulted mainly from the pioneering role of his work. Some of his breeding experiments can arouse the reader's sincere smile today, such as an attempt to feed a beaver with fish or serve cooked beans to a lynx In the margins of his mammal observations, Gilibert described also the place of their occurrence, extensive forests of the Grand Duchy of Lithuania. Read from the contemporary perspective, his thoughts are surprisingly relevant. In his praise of "primeval nature, free from human actions and not disturbed by accident or by the impatience of human desires" he sounds very similar to today's eulogists of the primeval forest of Białowieża.

Trans-ethnic meta-regression of genome-wide association studies accounting for ancestry increases power for discovery and improves fine-mapping resolution

PubMed Central

Mägi, Reedik; Horikoshi, Momoko; Sofer, Tamar; Mahajan, Anubha; Kitajima, Hidetoshi; Franceschini, Nora; McCarthy, Mark I.; Morris, Andrew P.

2017-01-01

Abstract Trans-ethnic meta-analysis of genome-wide association studies (GWAS) across diverse populations can increase power to detect complex trait loci when the underlying causal variants are shared between ancestry groups. However, heterogeneity in allelic effects between GWAS at these loci can occur that is correlated with ancestry. Here, a novel approach is presented to detect SNP association and quantify the extent of heterogeneity in allelic effects that is correlated with ancestry. We employ trans-ethnic meta-regression to model allelic effects as a function of axes of genetic variation, derived from a matrix of mean pairwise allele frequency differences between GWAS, and implemented in the MR-MEGA software. Through detailed simulations, we demonstrate increased power to detect association for MR-MEGA over fixed- and random-effects meta-analysis across a range of scenarios of heterogeneity in allelic effects between ethnic groups. We also demonstrate improved fine-mapping resolution, in loci containing a single causal variant, compared to these meta-analysis approaches and PAINTOR, and equivalent performance to MANTRA at reduced computational cost. Application of MR-MEGA to trans-ethnic GWAS of kidney function in 71,461 individuals indicates stronger signals of association than fixed-effects meta-analysis when heterogeneity in allelic effects is correlated with ancestry. Application of MR-MEGA to fine-mapping four type 2 diabetes susceptibility loci in 22,086 cases and 42,539 controls highlights: (i) strong evidence for heterogeneity in allelic effects that is correlated with ancestry only at the index SNP for the association signal at the CDKAL1 locus; and (ii) 99% credible sets with six or fewer variants for five distinct association signals. PMID:28911207

A Map Exercise for Teaching About the War in Vietnam.

ERIC Educational Resources Information Center

Heath, Douglas E.

1981-01-01

This paper describes a two-part exercise exploring Vietnam's ethnic and political geography as a way for college geography students to examine the lessons of Vietnam. Students analyze maps for geographic factors affecting nationalism and political changes between 1946-68. (AM)

Development of the profession and qualifications of adult educators in Lithuania in the context of reforms of adult education

NASA Astrophysics Data System (ADS)

Gedvilienė, Genutė; Tūtlys, Vidmantas; Lukošūnienė, Vilija; Zuzevičiūtė, Vaiva

2018-01-01

The Baltic countries regained their independence from the Soviet Union in the early 1990s and joined the European Union in 2004. This article seeks to explore institutional development and reforms of adult education and lifelong learning in Lithuania with respect to the processes, the actors and the context of socioeconomic change over the past 20 years. It also looks at the implications of these processes for the professionalisation of adult educators, referred to here as "adult learning teachers" (ALTs). The authors begin with an analysis of the historical-institutional and political-economical aspects of the development of adult education and lifelong learning by providing a retrospective of institutional change in Lithuania. They then move on to analyse the existing institutional and legal arrangements of adult education which shape and institutionalise the profession and qualifications of ALTs. Their empirical research reveals the opinions of Lithuanian ALTs on their current professional occupational profile and its future development.

Impact of anthropogenic pressure on the formation of population structure and genetic diversity of raccoon dog Nyctereutes procyonoides

PubMed Central

Griciuvienė, Loreta; Paulauskas, Algimantas; Radzijevskaja, Jana; Žukauskienė, Judita; Pūraitė, Irma

2016-01-01

Abstract The raccoon dog Nyctereutes procyonoides experienced an active introduction and acclimatization in the European part of Russia followed by its migration to and colonization in the neighboring countries. Eventually, it has spread rapidly into many European countries. N. procyonoides probably invaded Lithuania from the neighboring countries of Belarus and Latvia where the species was introduced. However, the data on genetic diversity and population structure of the raccoon dogs in the recently invaded territories are still scarce. The objectives of this study were to investigate genetic diversity of N. procyonoides in Lithuania after acclimatization, and to assess the impact of anthropogenic pressure on the formation of population structure. A total of 147 N. procyonoides individuals collected from different regions of Lithuania were genotyped using 17 microsatellite markers. The microsatellite analysis of raccoon dogs indicated high levels of genetic diversity within the population. The Bayesian clustering analysis in STRUCTURE identified 4 genetic clusters among sampled raccoon dogs that could not reveal a clear separation between subpopulations. The widespread distribution of raccoon dogs in Lithuania, high level of genetic variation observed within subpopulations, and low level of variation portioned among subpopulations suggest migration and gene flow among locations. The significant correlation between genetic and geographic distances indicated isolation that reflected the distance between locations. The fencing of highways and very intensive traffic could be barriers to gene flow between the western and eastern sampling areas of raccoon dogs. PMID:29491930

The epidemiology of road traffic injuries in the Republic of Lithuania, 1998-2007.

PubMed

Lunevicius, Raimundas; Herbert, Hadley K; Hyder, Adnan A

2010-12-01

This article highlights the epidemiology of road traffic injury (RTI) in Lithuania between 1998 and 2007. The purpose of this study is to explore the incidence of RTI, age-standardized mortality rates (ASMR), gender-specific rates and the RTI profile of different user groups. In doing so, this analysis attempts to emphasize the need for RTI prevention policies and programmes. Six databases were analysed using ICD-10 codes V01-V99, pertaining to the causes of road traffic crashes. Data between 1998 and 2007 were obtained from these databases to identify and calculate RTI incidence and mortality rates. This was then analysed with regard to ASMR, gender, user groups and the use of alcohol. In 2007, RTI incidence in Lithuania was reported as 270/100,000 people, 10.7% higher than in 1998. ASMR declined from 28 deaths per 100,000 in 1998 to 25 deaths per 100,000 in 2007. Between 1998 and 2007, the male ASMR declined from 46 to 40 deaths per 100,000 and the female ASMR decreased from 13 to 11 deaths per 100,000. Car occupant and pedestrian fatalities comprised 87% of all RTI deaths. Thirty-four percent of those injured and 21% of the dead were under influence of alcohol. From 1998 to 2007, the incidence of RTI has worsened and mortality rates remain high in Lithuania. Alcohol remains a prominent risk factor of traffic injury and death. The need to develop effective prevention programmes to address traffic injury is essential.

Governing "Suzhi" and Curriculum Reform in Rural Ethnic China: Viewpoints from the Miao and Dong Communities in Qiandongnan

ERIC Educational Resources Information Center

Wu, Jinting

2012-01-01

This article examines the uptake of "suzhi"--roughly glossed as "quality"--in China's recent curriculum reform called "suzhi jiaoyu" (Education for Quality) in the rural ethnic context of Qiandongnan. It engages with three layers of analysis. First is a brief etymological overview of "suzhi" to map out its…

Europe Today: A Reproducible Atlas. 1996 Revised Edition.

ERIC Educational Resources Information Center

World Eagle, Inc., Wellesley, MA.

This book contains blank outline maps of the European continent and tables and graphics depicting various aspects of Europe. Sections of the book include: (1) "Same Scale Maps, Silhouettes, Distances, Area"; (2) "Population"; (3) "Demographics, Ethnic, Religion, Health"; (4) "Economic, GDP, Import, Export,…

[GEOLOGICAL OVERVIEW OF THE VILNIUS REGION BY J. E. GILIBERT (1741-1814), THE FIRST PROFESSOR OF NATURAL HISTORY AT THE UNIVERSITY OF VILNIUS].

PubMed

Tarkowski, Radosław

2015-01-01

In 1775-1783, Jean-Emmanuel Gilibert (1741-1814) stayed in Respublica Poloniae to oranize a veterinary school, the Royal Botanic Garden and the Royal School of Physicians in Grodno, and since 1781 he worked in Vilnius as Professor of Natural History at the Principal School of the Grand Duchy of Lithuania. Little is known about his work conducted in Lithuania in the field of geology and earth sciences. The author has decided, on the basis of Gilibert's publications and analysis of the literature (works of J. Garbowska and P. Daszkiewicz and others), to present his teaching and research activities in this field. In Grodno, Gilibert looked after and multiplied the collections of the natural history cabinet at the Royal School of Physicians, renowned for its rich mineralogical and fossil collections watched and admired by, among others, King Stanisław August, J. Bernoulli (1744-1807) and M. Patrin (1742-1815) who mentions the amber rosary with a different species of insects preserved in each bead. Gilibert's tours around Lithuania were the opportunity to enlarge the geological collections and to adapt them to the needs of the school. He also appreciated the importance of ordinary specimens representing the geology of the area. These specimens not only enriched the natural history cabinet, but also defined the way of working and collecting. Ha was the first to found and gather fossil animals from near Grodno. The signs of mineralogical and geological interests of Gilibert can be found in the works of other authors of that epoch (L. Viteta (1736-1809) and J. Bernoulli). In Vilnius, Gilibert conducted a one year-long full lecture on natural history (zoology, botany and mineralogy). In his lectures on mineralogy, he presented not only the systematics, but also emphasized the usefulness of minerals in medicine, for the production of ornamental items and in different sectors of the economy. He adapted the process of teaching to the needs of practical life, based on observations and experiments, and was using the local wildlife specimens in his lectures. Thanks to the French naturalist, the teaching of natural science remained at a good European level since the time the Department was founded at the University of Vilnius. A treatise on physical geography of the Grand Duchy of Lithuania is Gilibert's best-known published work in Poland. Based on own observations, he determined, e.g., the causes of drying of ponds and marshes, as well as of the formation of peat, limonitic iron and ocher, the origin of rivers in Lithuania and the presence of amber, and described a number of fossils. He provided the characteristics of geological deposits (now included in the Quaternary), described their origin and age, and drew attention to the issues of dynamic geology (e.g. erosional activity of rainwater, river erosion, formation of sand dunes). From the period of his eight-year stay in Lithuania, Gilibert also submitted observations on the climate of Lithuania, documented by temperature measurements. He indicated that the climate of this part of Europe was milder than the French believed, with clearly noticeable two seasons: winter and summer. He pointed out that the autumn rains give rise to muddy areas persisting to the end of November, and the most severe frost, usually several days long, occurs in late December and January, when the winds blow from the northeast. June and July are typically the hottest months, but the northern winds sometimes cause July ground frosts. He compared Lithuania's climate to that of the Alpine foreland. Gilibert was the first scholar who studied the natural environment of Lithuania based on scientific principles. Interesting are his observations on the amber resin, for example, unequivocal statement that amber is a resin, at the time when the idea was still much discussed. Worth noting are the geological elements in the physiographic description of Lithuania, published by Gilibert (1806) in Histoires des Plantes d'Europe. It should also be pointed to the methodological aspect of Gilibert's works: the facts precede interpretations, the results are attempted to be universalized by transposition into areas other than those investigated by Gilibert, and the observations are linked with scientific theories, which were new at those times, in the field of geology, chemistry and physics. Gilibert's descriptions were often the first ones available to the naturalists in western and southern Europe. They were all the more valuable that contained a lot of data on the geology, meteorology, physical geography etc., useful in various fields.

Soil mapping and processes modelling for sustainable land management: a review

NASA Astrophysics Data System (ADS)

Pereira, Paulo; Brevik, Eric; Muñoz-Rojas, Miriam; Miller, Bradley; Smetanova, Anna; Depellegrin, Daniel; Misiune, Ieva; Novara, Agata; Cerda, Artemi

2017-04-01

Soil maps and models are fundamental for a correct and sustainable land management (Pereira et al., 2017). They are an important in the assessment of the territory and implementation of sustainable measures in urban areas, agriculture, forests, ecosystem services, among others. Soil maps represent an important basis for the evaluation and restoration of degraded areas, an important issue for our society, as consequence of climate change and the increasing pressure of humans on the ecosystems (Brevik et al. 2016; Depellegrin et al., 2016). The understanding of soil spatial variability and the phenomena that influence this dynamic is crucial to the implementation of sustainable practices that prevent degradation, and decrease the economic costs of soil restoration. In this context, soil maps and models are important to identify areas affected by degradation and optimize the resources available to restore them. Overall, soil data alone or integrated with data from other sciences, is an important part of sustainable land management. This information is extremely important land managers and decision maker's implements sustainable land management policies. The objective of this work is to present a review about the advantages of soil mapping and process modeling for sustainable land management. References Brevik, E., Calzolari, C., Miller, B., Pereira, P., Kabala, C., Baumgarten, A., Jordán, A. (2016) Historical perspectives and future needs in soil mapping, classification and pedological modelling, Geoderma, 264, Part B, 256-274. Depellegrin, D.A., Pereira, P., Misiune, I., Egarter-Vigl, L. (2016) Mapping Ecosystem Services in Lithuania. International Journal of Sustainable Development and World Ecology, 23, 441-455. Pereira, P., Brevik, E., Munoz-Rojas, M., Miller, B., Smetanova, A., Depellegrin, D., Misiune, I., Novara, A., Cerda, A. (2017) Soil mapping and process modelling for sustainable land management. In: Pereira, P., Brevik, E., Munoz-Rojas, M., Miller, B. (Eds.) Soil mapping and process modelling for sustainable land use management (Elsevier Publishing House) ISBN: 9780128052006

Africa Today: A Reproducible Atlas. 1996 Revised Edition. World Eagle's Today Series.

ERIC Educational Resources Information Center

Independent Broadcasting Associates, Inc., Littleton, MA.

This book contains blank outline maps of the continent or region, tables, and graphics depicting various aspects of Africa. Sections of the book include: (1) "Same Scale Maps, Silhouettes, Distances, Area"; (2) "Population"; (3) "Demographics, Education, Ethnic, Religion, Health"; (4) "Climate, Land,…

The role of self-defined race/ethnicity in population structure control.

PubMed

Liu, X-Q; Paterson, A D; John, E M; Knight, J A

2006-07-01

Population-based association studies are powerful tools for the genetic mapping of complex diseases. However, this method is sensitive to potential confounding by population structure. While statistical methods that use genetic markers to detect and control for population structure have been the focus of current literature, the utility of self-defined race/ethnicity in controlling for population structure has been controversial. In this study of 1334 individuals, who self-identified as either African American, European American or Hispanic, we demonstrated that when the true underlying genetic structure and the self-defined racial/ethnic groups were roughly in agreement with each other, the self-defined race/ethnicity information was useful in the control of population structure.

Lithuanian health care in transitional state: ethical problems

PubMed Central

Jakušovaitė, Irayda; Darulis, Žilvinas; Žekas, Romualdas

2005-01-01

Background Throughout the economic and political reforms in post-communist countries, significant changes have also occurred in public morality. One of the tasks of the Lithuanian health policy is to create mechanisms for strengthening the significance of ethical considerations in the decision-making processes concerning health care of individuals and groups of individuals, as well as considering the positions of physicians and the health care system itself in a general way. Thus, health care ethics could be analyzed at two levels: the micro level (the ethics of doctor-patient relationships) and the macro level (the ethics of health policy-making, which can be realized by applying the principles of equal access, reasonable quality, affordable care and shared responsibilities). To date, the first level remains dominant, but the need arises for our attention to refocus now from the micro level to the patterns of managing and delivering care, managing the health care resources, and conducting business practices. Discussion In attempting to increase the efficiency of health services in Lithuania, a common strategy has been in place for the last fifteen years. Decentralization and privatization have been implemented as part of its policy to achieve greater efficiency. Although decentralization in theory is supposed to improve efficiency, in practice the reform of decentralization has still to be completely implemented in Lithuania. Debates on health policy in Lithuania also include the issue of private versus public health care. Although the approach of private health care is changing in a positive way, it is obvious that reduced access to health services is the most vulnerable aspect. In the Lithuanian Health Program adopted in July 1998, the target of equity was stressed, stating that by 2010, differences in health and health care between various socio-economic groups should be reduced by 25%. Summary The restructuring of health care system in Lithuania should be based on a balance between decentralization and centralization, and between public and private health care sectors. Successful transition requires a balanced role of the government. Today it is obvious in Lithuania that continuous encouragement to make sacrifices was not enough to induce the system to function well, and in an ethical manner. PMID:16281969

Barriers to access to opioid medicines for patients with opioid dependence: a review of legislation and regulations in eleven central and eastern European countries.

PubMed

Vranken, Marjolein J M; Mantel-Teeuwisse, Aukje K; Jünger, Saskia; Radbruch, Lukas; Scholten, Willem; Lisman, John A; Subataite, Marija; Schutjens, Marie-Hélène D B

2017-06-01

Barriers linked to drug control systems are considered to contribute to inequitable access to controlled medicines, leaving millions of people in pain and suffering. Most studies focus on access to opioids for the treatment of severe (cancer) pain. This study aims to identify specific access barriers for patients with opioid dependence in legislation and regulations of 11 central and eastern European countries. This study builds on a previous analysis of legislation and regulations as part of the EU 7th Framework Access To Opioid Medication in Europe (ATOME) project. An in-depth analysis was undertaken to determine specific barriers for patients with opioid dependence in need of opioid analgesics or opioid agonist therapy (OAT). For each country, the number and nature of specific potential barriers for these patients were assessed according to eight categories: prescribing; dispensing; manufacturing; usage; trade and distribution; affordability; penalties; and other. An additional keyword search was conducted to minimize the omission of barriers. Barriers in an additional category, language, were recorded qualitatively. Countries included Bulgaria, Cyprus, Estonia, Greece, Hungary, Latvia, Lithuania, Serbia, Slovakia, Slovenia and Turkey. Ten of the 11 countries (all except Estonia) showed specific potential barriers in their legislation and regulations. The total number of barriers varied from two (Slovenia) to 46 (Lithuania); the number of categories varied from one (Slovenia) to five (Lithuania). Most specific potential barriers were shown in the categories 'prescribing', 'usage' and 'other'. The total number in a single category varied from one to 18 (Lithuania, prescribing). Individual differences between countries in the same specific potential barrier were shown; for example, variation in minimum age criteria for admission to OAT ranging from 15 (Lithuania, in special cases) to 20 years (Greece). All countries had stigmatizing language in their legislation. Patients with opioid dependence are likely to experience specific barriers to accessing opioids in addition to those experienced by other non-dependent patients. © 2017 Society for the Study of Addiction.

Uncertainty analysis of moderate- versus coarse-scale satellite fire products for quantifying agricultural burning: Implications for Air Quality in European Russia, Belarus, and Lithuania

NASA Astrophysics Data System (ADS)

McCarty, J. L.; Krylov, A.; Prishchepov, A. V.; Banach, D. M.; Potapov, P.; Tyukavina, A.; Rukhovitch, D.; Koroleva, P.; Turubanova, S.; Romanenkov, V.

2015-12-01

Cropland and pasture burning are common agricultural management practices that negatively impact air quality at a local and regional scale, including contributing to short-lived climate pollutants (SLCPs). This research focuses on both cropland and pasture burning in European Russia, Lithuania, and Belarus. Burned area and fire detections were derived from 500 m and 1 km Moderate Resolution Imaging Spectroradiometer (MODIS), 30 m Landsat 7 Enhanced Thematic Mapper Plus (ETM+), and Landsat 8 Operational Land Imager (OLI) data. Carbon, particulate matter, volatile organic carbon (VOCs), and harmful air pollutants (HAPs) emissions were then calculated using MODIS and Landsat-based estimates of fire and land-cover and land-use. Agricultural burning in Belarus, Lithuania, and European Russia showed a strong and consistent seasonal geographic pattern from 2002 to 2012, with the majority of fire detections occurring in March - June and smaller peak in July and August. Over this 11-year period, there was a decrease in both cropland and pasture burning throughout this region. For Smolensk Oblast, a Russian administrative region with comparable agro-environmental conditions to Belarus and Lithuania, a detailed analysis of Landsat-based burned area estimations for croplands and pastures and field data collected in summer 2014 showed that the agricultural burning area can be up to 10 times higher than the 1 km MODIS active fire estimates. In general, European Russia is the main source of agricultural burning emissions compared to Lithuania and Belarus. On average, all cropland burning in European Russia as detected by the MCD45A1 MODIS Burned Area Product emitted 17.66 Gg of PM10 while annual burning of pasture in Smolensk Oblast, Russia as detected by Landsat burn scars emitted 494.85 Gg of PM10, a 96% difference. This highlights that quantifying the contribution of pasture burning and burned area versus cropland burning in agricultural regions is important for accurately calculating carbonaceous emissions and emissions that negatively impact air quality.

Lithuanian health care in transitional state: ethical problems.

PubMed

Jakusovaite, Irayda; Darulis, Zilvinas; Zekas, Romualdas

2005-11-09

Throughout the economic and political reforms in post-communist countries, significant changes have also occurred in public morality. One of the tasks of the Lithuanian health policy is to create mechanisms for strengthening the significance of ethical considerations in the decision-making processes concerning health care of individuals and groups of individuals, as well as considering the positions of physicians and the health care system itself in a general way. Thus, health care ethics could be analyzed at two levels: the micro level (the ethics of doctor-patient relationships) and the macro level (the ethics of health policy-making, which can be realized by applying the principles of equal access, reasonable quality, affordable care and shared responsibilities). To date, the first level remains dominant, but the need arises for our attention to refocus now from the micro level to the patterns of managing and delivering care, managing the health care resources, and conducting business practices. In attempting to increase the efficiency of health services in Lithuania, a common strategy has been in place for the last fifteen years. Decentralization and privatization have been implemented as part of its policy to achieve greater efficiency. Although decentralization in theory is supposed to improve efficiency, in practice the reform of decentralization has still to be completely implemented in Lithuania. Debates on health policy in Lithuania also include the issue of private versus public health care. Although the approach of private health care is changing in a positive way, it is obvious that reduced access to health services is the most vulnerable aspect. In the Lithuanian Health Program adopted in July 1998, the target of equity was stressed, stating that by 2010, differences in health and health care between various socio-economic groups should be reduced by 25%. The restructuring of health care system in Lithuania should be based on a balance between decentralization and centralization, and between public and private health care sectors. Successful transition requires a balanced role of the government. Today it is obvious in Lithuania that continuous encouragement to make sacrifices was not enough to induce the system to function well, and in an ethical manner.

Analysis of high allergenicity airborne pollen dispersion: common ragweed study case in Lithuania.

PubMed

Šaulienė, Ingrida; Veriankaitė, Laura

2012-01-01

The appearance of ragweed pollen in the air became more frequent in northerly countries. Attention of allergologists and aerobiologists in these countries is focused on the phenomenon that Ambrosia plants found relatively sporadic but the amount of pollen is high in particular days. Over the latter decade, a matter of particular concern has been Ambrosia pollen, whose appearance in the air is determined by the plants dispersing it and meteorological processes that alter pollen release, dissemination, transport or deposition on surfaces. Pollen data used in this study were collected in three pollen-trapping sites in Lithuania. The data corresponding to 2006-2011 years of pollen monitoring were documented graphically and evaluated statistically. Analysis of the pollen data suggests that although the number of ragweed plants identified has not increased over the latter decade, the total pollen count has been on the increase during the recent period. The highest atmospheric pollen load is established on the last days of August and first days of September. The estimated effect of meteorological parameters on pollen dispersal in the air showed that in Lithuania ragweed pollen is recorded when the relative air humidity is about 70%, and the minimal air temperature is not less than 12°C. Analysis of wind change effect on pollen count indicates that pollen is most often recorded in the air when the changes in wind speed are low (1-2 m/s). We have established a regularity exhibiting an increase in ragweed pollen count conditioned by south-eastern winds in Lithuania.

Time trends of contact allergy to the European baseline series in Lithuania.

PubMed

Linauskienė, Kotryna; Malinauskienė, Laura; Blažienė, Audra

2017-06-01

Monitoring trends of positive patch test reactions is useful for epidemiological surveillance and contact allergy prevention, and has not previously been reported in Lithuania. To examine and compare changes in the prevalence of contact allergy to European baseline series allergens in adults with suspected contact dermatitis during a 9-year period. In this retrospective study, patch test results of 297 consecutive patients, tested with the European baseline series in 2014-2015, were analysed and compared with the data published earlier in Lithuania. The most common allergens were nickel sulfate (30.6%), methylisothiazolinone (MI) (13.5%), methylchloroisothiazolinone (MCI)/MI (7.4%), potassium dichromate (6.1%), cobalt chloride (6.1%), Myroxylon pereirae resin (5.4%), p-phenylenediamine (5.4%), fragrance mix I (4.7%), formaldehyde (4.4%), and methyldibromo glutaronitrile (3.7%). Increases in the prevalence of sensitization to MCI/MI (2.3% in 2006-2008 and 7.4% in 2014-2015; p < 0.0001) and nickel sulfate (16.4% in 2006-2008 and 30.6% in 2014-2015; p < 0.0001) and decreases in the prevalence of sensitization to paraben mix (3.2% in 2006-2008 and 0.3% in 2014-2015; p = 0.006) were observed. Prevalences for the other allergens remained stable or showed a decreasing trend (Myroxylon pereirae resin; p = 0.06). This study provides current information on the prevalence of contact allergy in Lithuania. Changing trends in sensitivity to some allergens probably reflect changes in exposure. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Educational differences in incidence of cancer in Lithuania, 2001-2009: evidence from census-linked cancer registry data.

PubMed

Smailyte, Giedre; Jasilionis, Domantas; Vincerzevskiene, Ieva; Krilaviciute, Agne; Ambrozaitiene, Dalia; Stankuniene, Vladislava; Shkolnikov, Vladimir M

2015-05-01

This study used population-based census-linked cancer incidence data to identify patterns of educational differentials in the risk of cancer by detailed sites of cancer in Lithuania. The study is based on the linkage between all records of the 2001 population census, all records from the Lithuanian Cancer Registry (cancer incidence), and all death and emigration records from Statistics Lithuania for the period between 6 April 2001 and 31 December 2009. The study population (cohort) includes all permanent residents of Lithuania aged 30-74 years on the day of the census (6 April 2001). The study found that cancers of the lip, mouth, and pharynx, esophagus, stomach, larynx, urinary bladder, pancreas, and lung for men and cancers of the cervix uteri, lung, and colon for women show a statistically significant inverse educational gradient with excess incidence in the lowest educational group. At the same time, a reversed cancer risk gradient with the highest incidence for the higher education group was observed for thyroid cancer, melanoma, nonmelanoma skin cancers, and non-Hodgkin lymphomas. This group also includes prostate cancer, kidney cancer, and multiple myeloma for men and cancer of the pancreas, breast cancer, cancer of the colon, and cancer of the uterus for women. The associations between education and cancer incidence observed in this study reflect the concordance between social status and lifestyle-related risk factors for cancer. Cancer awareness in society has also contributed toward the observed higher risk of cancer, which is usually promoted more by patients with higher education.

Sand incursion into temperate (Lithuania) and tropical (the Bahamas) maritime vegetation: Georadar visualization of target-rich aeolian lithosomes

NASA Astrophysics Data System (ADS)

Buynevich, Ilya V.; Savarese, Michael; Curran, H. Allen; Bitinas, Albertas; Glumac, Bosiljka; Pupienis, Donatas; Kopcznski, Karen; Dobrotin, Nikita; Gnivecki, Perry; Boush, Lisa Park; Damušytė, Aldona

2017-08-01

Interaction of windblown sand with maritime vegetation, either as dune migration or episodic grain transport is a common phenomenon along many sandy coasts. Vegetation introduces antecedent surface roughness, especially when scaled to the landform height, but its role may be concealed if overwhelmed by aeolian incursion and burial. Where field observations and cores lack detail for characterizing this complex process, ground-penetrating radar (GPR) offers continuous visualization of aeolian sequences. Along the Curonian Spit, Lithuania, dune reactivation phases resulted in massive invasion of siliciclastic sand triggered by natural perturbations and land clearance. Massive (>30 m high) dunes entombed mature pine, oak, and alder stands and this process is ongoing. Mid-frequency (200 MHz) georadar surveys reveal landward-dipping lateral accretion surfaces interrupted by high-amplitude point-source anomalies produced by recently buried trees. In tropical regions, dense vegetation and potential for rapid lithification of carbonate sand results in more complex internal structures. Along the windward coast of San Salvador Island, the Bahamas, a massive dune has buried several generations of maritime scrubland, resulting in highly chaotic reflection pattern and high target density. On a nearby Little Exuma Island, numerous reentrants in aeolianites promoted formation of blowouts and incursion of windblown sand 10-25 m into a silver thatch palm forest. High-frequency (800 MHz) GPR images resolve diffractions from trunks and roots buried by > 2 m of oolitic sand. Basal refection morphology helps differentiate the irregular dune/beachrock surface from a smooth palm-frond mat. Aside from detecting and mapping buried vegetation, geophysical images capture its effect on sediment accumulation. This has the potential for differentiating its effect from other discordant structures within dunes (clasts, dissolution voids, trunk molds, burrows, and cultural remains).

Over 400 m.y. metamorphic history of the Fennoscandian lithospheric segment in the Proterozoic (the East European Craton)

NASA Astrophysics Data System (ADS)

Skridlaite, G.; Bogdanova, S.; Taran, L.; Baginski, B.; Krzeminska, E.; Wiszniewska, J.; Whitehouse, M.

2009-04-01

Several Palaeoproterozoic terranes in the Fennoscandian lithospheric segment of the East European Craton (EEC) evolved differently prior to their final amalgamation at c. 1.8 Ga. South-westward younging of the major tectono-thermal events characterizes the Baltic -Belarus region between the Baltic and Ukrainian Shields of the EEC. While at c.1.89-1.87 Ga and 1.85-1.84 Ga rocks of some northern and eastern terranes (Estonia, Belarus and eastern Lithuania) experienced syncollisional, moderate P metamorphism, subduction-related volcanic island arc magmatism still dominated southwestern terranes in Lithuania and Poland. The available age determinations of metamorphic zircon (SIMS/NORDSIM and TIMS methods, Stockholm, SHRIMP method, RSES, ANU, Canberra) and metamorphic monazite (TIMS, Stockholm and EPMA method, Warsaw University) allow to distinguish several metamorphic events related to major orogenic processes: - 1.90-1.87 Ga amphibolite-facies H/MP metamorphism occurred along with emplacements of juvenile TTG-type granitoids in the North Estonian and Lithuanian-Belarus terranes. They are coeval with the main accretionary growth of the crust in the Svecofennian Domain in the Baltic Shield (e.g. Lahtinen et al., 2005). - 1.84-1.79 Ga high-grade metamorphism affected sedimentary and igneous rocks in almost all the terranes and is assumed to have been related to the major aggregation of the EEC (Bogdanova et al, 2006, 2008). In the metasedimentary granulites of western Lithuania, a prograde metamorphism commenced with monazite growth prior garnet at 1.84-1.83 Ga. The sediments and mafic igneous rocks in Lithuania, felsic igneous rocks in NE Poland underwent peak metamorphism and deformation at 1.81-1.79 Ga (zircon and monazite ages). The 1.83-1.79 Ga metamorphism has the same age as a metamorphic imprint and strong shearing of the crust in central Sweden (Andersson et al., 2004). The postcollisional granulite metamorphism of mafic intrusions at 1.80-1.79 Ga in Belarus indicates that the NW-SE collision can have triggered the crustal/mantle disturbance along the Fennoscandia-Sarmatia suture zone. - c. 1.7-1.6 Ga moderate PT metamorphic overprint and deformation of 1.83-1.82 Ga magmatic charnockites and c. 1.8 Ga metamorphic granulites in western Lithuania was recorded by the growth of a new garnet, zircon and monazite. The dated charnockites and metasediments contain metamorphic monazite of both 1.60-1.59 Ga and 1.7-1.65 Ga ages. These metamorphic events can reflect a distal influence of the 1.7-1.6 Ga Gothian orogeny in SW Fennoscandia (e.g. Ahall and Connelly, 2008). - 1.55-1.50 and 1.50-1.45 Ga events. In southern Lithuania, the 1.53-1.50 Ga AMCG magmatism was accompanied by high-grade metamorphism. Deformation and amphibolite facies metamorphism are marked by the 1.55-1.45 Ga 40Ar/39Ar ages of hornblende along EW-trending lineaments in central and southeastern Lithuania and Belarus. There are also indications of shearing and low grade, c. 1.50 Ga, metamorphism of metasedimentary rocks and charnockites in NW Lithuania and NE Poland. Altogether, the coeval AMCG magmatism, local high-grade and widespread low-grade metamorphism, and deformation can be manifestations of the Danopolonian orogeny, particularly prominent around the South Baltic Sea. This is a contribution to the project "The Precambrian structure of Baltica as a control of its recent environment and evolution" of the Visby Programme (the Swedish Institute) and SYNTHESYS project SE-TAF-1535. References Ahall, K.I. and Connelly, J.N., 2008. Precambrian Research, 161(3-4): 452-474. Andersson, U.B. et al., 2004, GFF 126, 16-17. Bogdanova, S. et al., 2006, Geological Society, London Memoirs, 32, pp. 599-628 Bogdanova, S. et al., 2008, Precambrian Research 160, 23-45. Lahtinen, R., et al., 2005. In: Precambrian Geology of Finland - Key to the Evolution of the Fennoscandian Shield. Elsevier, Amsterdam, 481-532

Environmentalism and community: connections and implications for social action

Treesearch

Benjamin J. Marcus; Allen M. Omoto; Patricia L. Winter

2011-01-01

This qualitative study explored conceptualizations of environmentalism and community, as well as the connections of ethnicity to these concepts in a small but diverse sample. Semistructured interviews were conducted with eight participants and included a conceptual content cognitive mapping procedure. The resulting maps were examined for themes and ideas about the key...

Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.

PubMed

Yin, Xianyong; Low, Hui Qi; Wang, Ling; Li, Yonghong; Ellinghaus, Eva; Han, Jiali; Estivill, Xavier; Sun, Liangdan; Zuo, Xianbo; Shen, Changbing; Zhu, Caihong; Zhang, Anping; Sanchez, Fabio; Padyukov, Leonid; Catanese, Joseph J; Krueger, Gerald G; Duffin, Kristina Callis; Mucha, Sören; Weichenthal, Michael; Weidinger, Stephan; Lieb, Wolfgang; Foo, Jia Nee; Li, Yi; Sim, Karseng; Liany, Herty; Irwan, Ishak; Teo, Yikying; Theng, Colin T S; Gupta, Rashmi; Bowcock, Anne; De Jager, Philip L; Qureshi, Abrar A; de Bakker, Paul I W; Seielstad, Mark; Liao, Wilson; Ståhle, Mona; Franke, Andre; Zhang, Xuejun; Liu, Jianjun

2015-04-23

Psoriasis is a common inflammatory skin disease with complex genetics and different degrees of prevalence across ethnic populations. Here we present the largest trans-ethnic genome-wide meta-analysis (GWMA) of psoriasis in 15,369 cases and 19,517 controls of Caucasian and Chinese ancestries. We identify four novel associations at LOC144817, COG6, RUNX1 and TP63, as well as three novel secondary associations within IFIH1 and IL12B. Fine-mapping analysis of MHC region demonstrates an important role for all three HLA class I genes and a complex and heterogeneous pattern of HLA associations between Caucasian and Chinese populations. Further, trans-ethnic comparison suggests population-specific effect or allelic heterogeneity for 11 loci. These population-specific effects contribute significantly to the ethnic diversity of psoriasis prevalence. This study not only provides novel biological insights into the involvement of immune and keratinocyte development mechanism, but also demonstrates a complex and heterogeneous genetic architecture of psoriasis susceptibility across ethnic populations.

Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility

PubMed Central

Yin, Xianyong; Low, Hui Qi; Wang, Ling; Li, Yonghong; Ellinghaus, Eva; Han, Jiali; Estivill, Xavier; Sun, Liangdan; Zuo, Xianbo; Shen, Changbing; Zhu, Caihong; Zhang, Anping; Sanchez, Fabio; Padyukov, Leonid; Catanese, Joseph J.; Krueger, Gerald G.; Duffin, Kristina Callis; Mucha, Sören; Weichenthal, Michael; Weidinger, Stephan; Lieb, Wolfgang; Foo, Jia Nee; Li, Yi; Sim, Karseng; Liany, Herty; Irwan, Ishak; Teo, Yikying; Theng, Colin T. S.; Gupta, Rashmi; Bowcock, Anne; De Jager, Philip L.; Qureshi, Abrar A.; de Bakker, Paul I. W.; Seielstad, Mark; Liao, Wilson; Ståhle, Mona; Franke, Andre; Zhang, Xuejun; Liu, Jianjun

2015-01-01

Psoriasis is a common inflammatory skin disease with complex genetics and different degrees of prevalence across ethnic populations. Here we present the largest trans-ethnic genome-wide meta-analysis (GWMA) of psoriasis in 15,369 cases and 19,517 controls of Caucasian and Chinese ancestries. We identify four novel associations at LOC144817, COG6, RUNX1 and TP63, as well as three novel secondary associations within IFIH1 and IL12B. Fine-mapping analysis of MHC region demonstrates an important role for all three HLA class I genes and a complex and heterogeneous pattern of HLA associations between Caucasian and Chinese populations. Further, trans-ethnic comparison suggests population-specific effect or allelic heterogeneity for 11 loci. These population-specific effects contribute significantly to the ethnic diversity of psoriasis prevalence. This study not only provides novel biological insights into the involvement of immune and keratinocyte development mechanism, but also demonstrates a complex and heterogeneous genetic architecture of psoriasis susceptibility across ethnic populations. PMID:25903422

Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin.

PubMed

Liu, Ching-Ti; Raghavan, Sridharan; Maruthur, Nisa; Kabagambe, Edmond Kato; Hong, Jaeyoung; Ng, Maggie C Y; Hivert, Marie-France; Lu, Yingchang; An, Ping; Bentley, Amy R; Drolet, Anne M; Gaulton, Kyle J; Guo, Xiuqing; Armstrong, Loren L; Irvin, Marguerite R; Li, Man; Lipovich, Leonard; Rybin, Denis V; Taylor, Kent D; Agyemang, Charles; Palmer, Nicholette D; Cade, Brian E; Chen, Wei-Min; Dauriz, Marco; Delaney, Joseph A C; Edwards, Todd L; Evans, Daniel S; Evans, Michele K; Lange, Leslie A; Leong, Aaron; Liu, Jingmin; Liu, Yongmei; Nayak, Uma; Patel, Sanjay R; Porneala, Bianca C; Rasmussen-Torvik, Laura J; Snijder, Marieke B; Stallings, Sarah C; Tanaka, Toshiko; Yanek, Lisa R; Zhao, Wei; Becker, Diane M; Bielak, Lawrence F; Biggs, Mary L; Bottinger, Erwin P; Bowden, Donald W; Chen, Guanjie; Correa, Adolfo; Couper, David J; Crawford, Dana C; Cushman, Mary; Eicher, John D; Fornage, Myriam; Franceschini, Nora; Fu, Yi-Ping; Goodarzi, Mark O; Gottesman, Omri; Hara, Kazuo; Harris, Tamara B; Jensen, Richard A; Johnson, Andrew D; Jhun, Min A; Karter, Andrew J; Keller, Margaux F; Kho, Abel N; Kizer, Jorge R; Krauss, Ronald M; Langefeld, Carl D; Li, Xiaohui; Liang, Jingling; Liu, Simin; Lowe, William L; Mosley, Thomas H; North, Kari E; Pacheco, Jennifer A; Peyser, Patricia A; Patrick, Alan L; Rice, Kenneth M; Selvin, Elizabeth; Sims, Mario; Smith, Jennifer A; Tajuddin, Salman M; Vaidya, Dhananjay; Wren, Mary P; Yao, Jie; Zhu, Xiaofeng; Ziegler, Julie T; Zmuda, Joseph M; Zonderman, Alan B; Zwinderman, Aeilko H; Adeyemo, Adebowale; Boerwinkle, Eric; Ferrucci, Luigi; Hayes, M Geoffrey; Kardia, Sharon L R; Miljkovic, Iva; Pankow, James S; Rotimi, Charles N; Sale, Michele M; Wagenknecht, Lynne E; Arnett, Donna K; Chen, Yii-Der Ida; Nalls, Michael A; Province, Michael A; Kao, W H Linda; Siscovick, David S; Psaty, Bruce M; Wilson, James G; Loos, Ruth J F; Dupuis, Josée; Rich, Stephen S; Florez, Jose C; Rotter, Jerome I; Morris, Andrew P; Meigs, James B

2016-07-07

Knowledge of the genetic basis of the type 2 diabetes (T2D)-related quantitative traits fasting glucose (FG) and insulin (FI) in African ancestry (AA) individuals has been limited. In non-diabetic subjects of AA (n = 20,209) and European ancestry (EA; n = 57,292), we performed trans-ethnic (AA+EA) fine-mapping of 54 established EA FG or FI loci with detailed functional annotation, assessed their relevance in AA individuals, and sought previously undescribed loci through trans-ethnic (AA+EA) meta-analysis. We narrowed credible sets of variants driving association signals for 22/54 EA-associated loci; 18/22 credible sets overlapped with active islet-specific enhancers or transcription factor (TF) binding sites, and 21/22 contained at least one TF motif. Of the 54 EA-associated loci, 23 were shared between EA and AA. Replication with an additional 10,096 AA individuals identified two previously undescribed FI loci, chrX FAM133A (rs213676) and chr5 PELO (rs6450057). Trans-ethnic analyses with regulatory annotation illuminate the genetic architecture of glycemic traits and suggest gene regulation as a target to advance precision medicine for T2D. Our approach to utilize state-of-the-art functional annotation and implement trans-ethnic association analysis for discovery and fine-mapping offers a framework for further follow-up and characterization of GWAS signals of complex trait loci. Copyright © 2016 American Society of Human Genetics. All rights reserved.

Hot-spot analysis applied to the identification of potential high and low regulating, providing and cultural ecosystem services in Vilnius Region (Lithuania)

NASA Astrophysics Data System (ADS)

Pereira, Paulo; Daniel, Depellegrin; Egarter-Vigl, Lukas; Cerda, Artemi; Estebaranz, Ferran; Misiune, Ieva

2017-04-01

Ecosystem services (ES) potential assessment is crucial for a correct territorial planning at different scales of analysis (Depellegrin et al., 2016). In urban and peri-urban areas, sprawl, grazing and unsustainable agriculture practices contributed to land degradation and de decrease of the quality and quantity of the services provided by these areas (Eldridge and Delgado-Baquerizo, 2017; Favretto et al., 2017). In order to understand the spatial pattern of these impacts, mapping ES potential is key to understand the areas that need to be restored and protected for an unsustainable use (Brevik et al., 2016; Egarter-Vigl et al., 2017; Pereira et al., 2017). Hot-spot analysis is a good method to identify clusters of areas with high and low capacity for ES capacity. This analysis is very useful to detect homogeneous areas, where ES have high or low quality. The objective of this work is to apply a hot-spot analysis to detect areas with high/low capacity for Regulating, Provision, Cultural and Total ES in Vilnius region. ES potential was carried out based on the matrix developed by Burkhard et al. (2009), which ranks ES capacity from 0= no capacity to 5=very high relevant capacity to a different land use type. The results showed that regulating, providing and cultural and total ES have a significant dispersed (low-clustered) pattern: Regulating (Z-score=-19.28, p<0.001), Providing (Z-score=-29.28, p<0.001) Cultural (Z-score=-8.13, p<0.001) and Total (Z-score=-22.46, p<0.001). This shows that ES capacity in Vilnius area is extremely fragmented and there is a lack of connectivity between the areas with high capacity of ES. There is lack of green corridors and connectivity between green areas is attributed to the urban sprawl observed in Vilnius area (Pereira et al., 2014). References Brevik, E., Calzolari, C., Miller, B., Pereira, P., Kabala, C., Baumgarten, A., Jordán, A. (2016) Historical perspectives and future needs in soil mapping, classification and pedological modelling, Geoderma, 264, Part B, 256-274. Burkhard B, Kroll F, Müller F, Windhorst W. 2009. Landscapes' capacities to provide ecosystem services- a concept for land-cover based assessments. Landscape Online. 15, 1-22. Depellegrin, D.A., Pereira, P., Misiune, I., Egarter-Vigl, L. Mapping Ecosystem Services potential in Lithuania. International Journal of Sustainable Development and World Ecology, 23, 441-455. Egarter-Vigl, L., Depellegrin, D., Pereira, P., De Groot, D., Tappeiner, U. (2017) Mapping the ecosystem service delivery chain: Capacity, flow, and demand pertaining to aesthetic experiences in mountain landscapes, Science of the Total Environment, 574, 442-436. Eldridge, D.J., Delgado-Baquerizo, M. (2017) Continental-scale impacts of livestock grazing on ecosystem supporting and regulating services. Land Degradation and Development. DOI: 10.1002/ldr.2668 Favretto, N., Lueding, E., Stringer, L., Dougill, A.J. (2017) Valuing ecosystem services in semi-arid rangelands through stochastic simulation. Land Degradation and Development. DOI: 10.1002/ldr.2590 Pereira, P., Brevik, E., Munoz-Rojas, M., Miller, B., Smetanova, A., Depellegrin, D., Misiune, I., Novara, A., Cerda, A. (2017) Soil mapping and process modelling for sustainable land management. In: Pereira, P., Brevik, E., Munoz-Rojas, M., Miller, B. (Eds.) Soil mapping and process modelling for sustainable land use management (Elsevier Publishing House) ISBN: 9780128052006 Pereira, P., Monkevicius, A., Siarova, A. (2014) Public perception of the Environmental, Social and Economic impacts of Urban Sprawl in Vilnius, Societal Studies, 6, 256 - 290.

Impact of hemodialysis dose and frequency on survival of patients on chronic hemodialysis in Lithuania during 1998-2005.

PubMed

Stankuvienė, Asta; Ziginskienė, Edita; Kuzminskis, Vytautas; Bumblytė, Inga Arūnė

2010-01-01

The question of the targets of dialysis dosing remains controversial since the beginning of the long-term dialysis treatment era. It is still uncertain if higher dialysis dose is better. The aim of our study was to investigate issues of dialysis dose in Lithuania during the period of 1998-2005 and to determine associations between hemodialysis dose and survival of patients on chronic hemodialysis. We analyzed data of all patients who started hemodialysis due to end-stage renal disease in Lithuania between January 1, 1998, and December 31, 2005. The information about hemodialysis frequency, duration, and adequacy (according to Kt/V) was obtained from medical documentation. The overall survival rate was estimated using the Kaplan-Meier method. Survival comparisons were made using the log-rank or Breslow tests. Univariate Cox proportional hazards analysis was used to select variables significantly associated with the risk of death; then these variables were included in multivariate Cox proportional hazards models. During the study period, from 2428 patients who started chronic hemodialysis, 58.5% of patients started hemodialysis three times a week. More than one-third (36.2%) of patients were dialyzed twice weekly, and 5.3% of patients started hemodialysis once weekly. Survival analysis revealed that patients dialyzed less than three times per week survived shorter than patients receiving a higher dialysis dose. Duration of HD session of ≤8 hours per week was an independent risk factor for mortality. A higher mean Kt/V was associated with better survival of patients on chronic hemodialysis. Dialysis frequency and weekly duration of HD sessions were dependent on HD accessibility in Lithuania during the period of 1998-2005. Better survival of patients on chronic hemodialysis was associated with a higher hemodialysis dose.

Epidemiological patterns of tick-borne encephalitis in Lithuania and clinical features in adults in the light of the high incidence in recent years: a retrospective study.

PubMed

Radzišauskienė, D; Žagminas, K; Ašoklienė, L; Jasionis, A; Mameniškienė, R; Ambrozaitis, A; Jančorienė, L; Jatužis, D; Petraitytė, I; Mockienė, E

2018-02-01

Lithuania is one of the countries with the highest incidence of tick-borne encephalitis (TBE) in Europe. The aim of this study was to describe the epidemiological patterns of TBE in Lithuania, and characterize clinical features in adults in the light of the high incidence in recent years. Surveillance data available on the website of the Centre for Communicable Diseases and AIDS of Lithuania were used to describe the epidemiological patterns of TBE. The retrospective study included 712 patients hospitalized in the Centre for Infectious Diseases and the Centre for Neurology of Vilnius University in the years 2005-2014. Tick-borne encephalitis incidence rates have been increasing by 8.5% per year for the 45-year period from 1970 to 2014. The joinpoint model finds two joinpoints at 1991 and 1994, with a significant decrease of 8.4% per year (P < 0.05) prior to the joinpoint at 1991, and a rise of 195.2% afterwards. TBE presented with meningoencephalitis in 556 cases (81.3%). A total of 129 patients (18%) had a severe case of the disease. The most common neurological signs were ataxia (579, 81.3%), meningeal signs (474, 66.5%) and tremor (338, 47.5%). Limb paresis was observed in 6.3% of patients. Five patients (0.7%) died, and 544 patients (76.7%) were discharged with sequelae. Intensified efforts in promoting TBE vaccination will be needed in the light of the high incidence and expanded spatial distribution. Significant prognostic factors for severe cases of the disease were age above 61 and delayed immune response of specific immunoglobulin G. © 2017 The Authors. European Journal of Neurology published by John Wiley & Sons Ltd on behalf of European Academy of Neurology.

Access to care in the Baltic States: did crisis have an impact?

PubMed

Karanikolos, Marina; Gordeev, Vladimir S; Mackenbach, Johan P; McKee, Martin

2016-04-01

In 2009, brief but deep economic crisis profoundly affected the three Baltic States: Estonia, Latvia and Lithuania. In response, all three countries adopted severe austerity measures with the shared goal of containing rising deficits, but employing different methods. In this article, we analyze the impact of the economic crisis and post-crisis austerity measures on health systems and access to medical services in the three countries. We use the EU-SILC data to analyze trends in unmet medical need in 2005-2012, and apply log-binomial regression to calculate the risk of unmet medical need in the pre- and post- crisis period. Between 2009 and 2012 unmet need has increased significantly in Latvia (OR: 1.24, 95% confidence interval (CI): 1.15-1.34) and Estonia (OR: 1.98, 95% CI: 1.72-2.27), but not Lithuania (OR: 0.84. 95% CI: 0.69-1.04). The main drivers of increased unmet need were inability to afford care in Latvia and long waiting lists in Estonia. The impact of the crisis on access to care in the three countries varied, as did the austerity measures affecting their health systems. Estonia and Latvia experienced worsening access to care, largely exacerbating already existing barriers. The example of Lithuania suggests that deterioration in access is not inevitable, once health policies prioritise maintenance and availability of existing services, or if there is room for reducing existing inefficiencies. Moreover, better financial preparedness of health systems in Estonia and Lithuania achieved some protection of the population from increasing unmet need due to the rising cost of medical care. © The Author 2015. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

Fleas (Siphonaptera) in the Nests of Dormice (Gliridae: Rodentia) in Lithuania.

PubMed

Lipatova, I; Stanko, M; Paulauskas, A; Spakovaite, S; Gedminas, V

2015-05-01

Negative effects of flea (Siphonaptera) parasitism on the host may be expressed in different ways. The aim of this study was to assess distribution of the flea fauna in nests of dormice in Lithuania. Nests of Glis glis (L.), Dryomys nitedula (Pallas), and Muscardinus avellanarius (L.) were collected from nest boxes in 2012 and 2013. Fleas were collected from nests in the laboratory and put into plastic tubes with 70% ethanol. Flea species were identified using morphological keys. From 400 nest boxes, 112 nests of dormice were collected from eight sites from mixed forests of central Lithuania. Twenty-three nests of G. glis were collected from nest boxes, with 16 of them containing 286 fleas belonging to four species: Ceratophyllus sciurorum (Schrank) (259), C. gallinae (Schrank) (23), Hystrichopsylla talpae (Curtis) (3), and Megabothris turbidus (Rothschild) (1). Fourteen nests of M. avellanarius were collected from nest boxes, 4 of which contained 224 fleas belonging to two species: C. sciurorum (221) and C. gallinae (3). Twenty-four nests of D. nitedula were collected from nest boxes, including 17 containing 207 fleas belonging to two species: C. sciurorum (205) and C. gallinae (2). Fifty-one nests of undetermined dormice species also were collected from nest boxes, 12 of them contained 395 fleas belonging to three species: C. sciurorum (374), Ctenophthalmus agyrtes (Heller) (19), and Ctenophthalmus assimilis (Taschenberg) (2). C. sciurorum was a predominant species in the nests of dormice. The occurrence of C. gallinae was documented in Lithuania for the first time. © The Authors 2015. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

High population increase rates.

PubMed

1991-09-01

In addition to its economic and ethnic difficulties, the USSR faces several pressing demographic problems, including high population increase rates in several of its constituent republics. It has now become clear that although the country's rigid centralized planning succeeded in covering the basic needs of people, it did not lead to welfare growth. Since the 1970s, the Soviet economy has remained sluggish, which as led to increase in the death and birth rates. Furthermore, the ideology that held that demography could be entirely controlled by the country's political and economic system is contradicted by current Soviet reality, which shows that religion and ethnicity also play a significant role in demographic dynamics. Currently, Soviet republics fall under 2 categories--areas with high or low natural population increase rates. Republics with low rates consist of Christian populations (Armenia, Moldavia, Georgia, Byelorussia, Russia, Lithuania, Estonia, Latvia, Ukraine), while republics with high rates are Muslim (Tadzhikistan, Uzbekistan, Turkmenistan, Kirgizia, Azerbaijan Kazakhstan). The later group has natural increase rates as high as 3.3%. Although the USSR as a whole is not considered a developing country, the later group of republics fit the description of the UNFPA's priority list. Another serious demographic issue facing the USSR is its extremely high rate of abortion. This is especially true in the republics of low birth rates, where up to 60% of all pregnancies are terminated by induced abortions. Up to 1/5 of the USSR's annual health care budget is spent on clinical abortions -- money which could be better spent on the production of contraceptives. Along with the recent political and economic changes, the USSR is now eager to deal with its demographic problems.

Multi-ethnic fine-mapping of 14 central adiposity loci.

PubMed

Liu, Ching-Ti; Buchkovich, Martin L; Winkler, Thomas W; Heid, Iris M; Borecki, Ingrid B; Fox, Caroline S; Mohlke, Karen L; North, Kari E; Adrienne Cupples, L

2014-09-01

The Genetic Investigation of Anthropometric Traits (GIANT) consortium identified 14 loci in European Ancestry (EA) individuals associated with waist-to-hip ratio (WHR) adjusted for body mass index. These loci are wide and narrowing the signals remains necessary. Twelve of 14 loci identified in GIANT EA samples retained strong associations with WHR in our joint EA/individuals of African Ancestry (AA) analysis (log-Bayes factor >6.1). Trans-ethnic analyses at five loci (TBX15-WARS2, LYPLAL1, ADAMTS9, LY86 and ITPR2-SSPN) substantially narrowed the signals to smaller sets of variants, some of which are in regions that have evidence of regulatory activity. By leveraging varying linkage disequilibrium structures across different populations, single-nucleotide polymorphisms (SNPs) with strong signals and narrower credible sets from trans-ethnic meta-analysis of central obesity provide more precise localizations of potential functional variants and suggest a possible regulatory role. Meta-analysis results for WHR were obtained from 77 167 EA participants from GIANT and 23 564 AA participants from the African Ancestry Anthropometry Genetics Consortium. For fine mapping we interrogated SNPs within ± 250 kb flanking regions of 14 previously reported index SNPs from loci discovered in EA populations by performing trans-ethnic meta-analysis of results from the EA and AA meta-analyses. We applied a Bayesian approach that leverages allelic heterogeneity across populations to combine meta-analysis results and aids in fine-mapping shared variants at these locations. We annotated variants using information from the ENCODE Consortium and Roadmap Epigenomics Project to prioritize variants for possible functionality. Published by Oxford University Press 2014. This work is written by (a) US Government employee(s) and is in the public domain in the US.

First detection of bluetongue virus serotype 14 in Poland.

PubMed

Orłowska, Anna; Trębas, Paweł; Smreczak, Marcin; Marzec, Anna; Żmudziński, Jan F

2016-07-01

Here, we present the first detected cases of bluetongue virus (BTV) in native cattle from Poland. The virus was found in animals located near the Polish-Belarusian and Polish-Lithuanian borders. The positive animals were detected through an official epidemiological surveillance program. A combination of type-specific real-time RT-PCR and phylogenetic tests revealed the presence of BTV serotype 14 (BTV-14). This serotype is highly homologous to the vaccine strain and BTV-14 present in Russia, Lithuania, and Spain (from an animal imported from Lithuania). The most probable route of virus introduction to Poland was transmission through midges. All of the cases were subclinical.

Population substructure in Cache County, Utah: the Cache County study

PubMed Central

2014-01-01

Background Population stratification is a key concern for genetic association analyses. In addition, extreme homogeneity of ethnic origins of a population can make it difficult to interpret how genetic associations in that population may translate into other populations. Here we have evaluated the genetic substructure of samples from the Cache County study relative to the HapMap Reference populations and data from the Alzheimer's Disease Neuroimaging Initiative (ADNI). Results Our findings show that the Cache County study is similar in ethnic diversity to the self-reported "Whites" in the ADNI sample and less homogenous than the HapMap CEU population. Conclusions We conclude that the Cache County study is genetically representative of the general European American population in the USA and is an appropriate population for conducting broadly applicable genetic studies. PMID:25078123

Assessing the risk for suicide in schizophrenia according to migration, ethnicity and geographical ancestry.

PubMed

Hettige, Nuwan C; Bani-Fatemi, Ali; Kennedy, James L; De Luca, Vincenzo

2017-02-09

Suicide is a leading cause of mortality among those afflicted by schizophrenia. Previous studies demonstrated that the stressors associated with immigration may lead to an onset of schizophrenia and suicide separately in susceptible individuals. However, no studies have shown whether immigration may lead to suicidal behaviour for individuals with schizophrenia. Our study proposes that an individual's geographical ancestry, ethnicity or migration status may be predictive of suicide risk in schizophrenia. In a sample of 276 participants with schizophrenia spectrum disorders, we conducted cross-sectional assessments to collect clinical information. Self-identified ethnicity and suicide history were collected through self-report questionnaires and interview-based scales. Ancestry was identified using 292 genetic markers from HapMap. Migrants were classified as those who immigrated to Canada during their lifetime. Using a regression analysis, we tested whether a history of migration, ethnicity or geographical ancestry were predictive of a history of suicide attempts. Our analysis failed to demonstrate a significant relationship between suicide history and migration, ethnicity or ancestry. However, ethnicity appears to be significantly associated with the number of psychiatric hospitalizations in our sample. Ethnicity and migration history are not predictive of previous suicide attempts. Ethnicity may be an important demographic factor affecting access to mental health resources and frequency of hospitalizations.

Type 2 diabetes mellitus: distribution of genetic markers in Kazakh population.

PubMed

Sikhayeva, Nurgul; Talzhanov, Yerkebulan; Iskakova, Aisha; Dzharmukhanov, Jarkyn; Nugmanova, Raushan; Zholdybaeva, Elena; Ramanculov, Erlan

2018-01-01

Ethnic differences exist in the frequencies of genetic variations that contribute to the risk of common disease. This study aimed to analyse the distribution of several genes, previously associated with susceptibility to type 2 diabetes and obesity-related phenotypes, in a Kazakh population. A total of 966 individuals belonging to the Kazakh ethnicity were recruited from an outpatient clinic. We genotyped 41 common single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes in other ethnic groups and 31 of these were in Hardy-Weinberg equilibrium. The obtained allele frequencies were further compared to publicly available data from other ethnic populations. Allele frequencies for other (compared) populations were pooled from the haplotype map (HapMap) database. Principal component analysis (PCA), cluster analysis, and multidimensional scaling (MDS) were used for the analysis of genetic relationship between the populations. Comparative analysis of allele frequencies of the studied SNPs showed significant differentiation among the studied populations. The Kazakh population was grouped with Asian populations according to the cluster analysis and with the Caucasian populations according to PCA. According to MDS, results of the current study show that the Kazakh population holds an intermediate position between Caucasian and Asian populations. A high percentage of population differentiation was observed between Kazakh and world populations. The Kazakh population was clustered with Caucasian populations, and this result may indicate a significant Caucasian component in the Kazakh gene pool.

The first large geological map of Central and Eastern Europe (1815)

NASA Astrophysics Data System (ADS)

Grigelis, Algimantas; Wójcik, Zbigniew; Narębski, Wojciech; Gelumbauskaitė, Leonora Živilė; Kozák, Jan; Czarniecki, Stanisław

2008-01-01

The first large geological map of Central and Eastern Europe was compiled by Stanisław Staszic in the early 19th century. The map is based on the geological survey that Staszic performed in different parts of Poland and adjacent areas. In 1814, Staszic presented his ideas on the geology and mineral sources of Poland and Lithuania. In 1815, he completed the book-length descriptive analysis O ziemorodztwie Karpatów i innych gór i równin Polski przez Stanisława Staszica, which was published in Warsaw and complemented by a large geological map of Central and Eastern Europe. His later studies were compiled in a historico-philosophical treatise titled Ród ludzki (1819-1820). The complete edition of Staszic's works, Dzieła, which also included these publications, appeared over 1816-1820. The geological field survey that he performed over several years, and his study of social-economic problems enabled Staszic to draw in great detail a geological map of the Carpathians, the Central Polish Highlands, Volhynia (modern Ukraine) and the Eastern Alps, as well as the areas of the Polish-Lithuanian Lowlands, the southern coast of the Baltic Sea, Polesye (modern Belarus), Moldova, Transylvania, and Hungary. Staszic was interested in the exploration of mineral deposits, particularly in Poland, which had rock salt, copper and iron ores, and coal. In his monograph and map, he adopted a stratigraphic subdivision based on types of rock contents and organic fossils, which was a slightly modified version of Werner's classification system. The lithological legend sets five classes and 135 different types of rock, and 15 types of ore deposits, using the French names for these. In general, Staszic was an advocate of Werner's paradigm; however, he did not follow exactly the ideas of the German geologist. Staszic's fundamental work recapitulates his views on geological history of Central and Eastern Europe, and brings to an end the Enlightment period in the geology of that part of Europe.

Disparities -- Healthy People 2020

MedlinePlus

... health based on their racial or ethnic group; religion; socioeconomic status; gender; age; mental health; cognitive, sensory, ... Contact Us Site Map Accessibility Privacy Policy Disclaimers Freedom of Information Act Healthy People 2010 Archive Nondiscrimination ...

Basal cell skin cancer and the risk of second primary cancers: a cancer registry-based study in Lithuania.

PubMed

Krilaviciute, Agne; Vincerzevskiene, Ieva; Smailyte, Giedre

2016-07-01

The aim of this population-based cohort study was to determine the risk of second primary cancer in basal cell carcinoma (BCC) patients in Lithuania. This analysis was based on patients diagnosed with BCC in Lithuania between 1998 and 2007 and followed until 2011. Standardized incidence ratios for subsequent cancers as a ratio of observed number of cancer cases in people with previous BCC diagnosis to the expected number of cancer cases in the underlying general population were calculated. After diagnosis of BCC, 1442 new cases of selected cancers were diagnosed. Compared with the general population, the incidence of all new primaries combined after BCC was very close to expected. Statistically meaningful increase in developing subsequent cancer was obtained for Hodgkin's lymphoma, prostate cancer, and leukemia in men, and for cancers of the lip, lung, and breast in women. Risk of melanoma and thyroid cancer was significantly elevated in both sexes. Relative risk of cancer of the eye was increased although not significant. In our study, we found increased cancer risk for cancers related to sun exposure. In addition, increased risks were identified for Hodgkin's lymphoma, thyroid cancer, leukemia, prostate, and breast cancer in BCC patients. Copyright © 2016 Elsevier Inc. All rights reserved.

Suicidal ideation, risk factors, and communication with parents. An HBSC study on school children in Estonia, Lithuania, and Luxembourg.

PubMed

Mark, Lauraliisa; Samm, Algi; Tooding, Liina-Mai; Sisask, Merike; Aasvee, Katrin; Zaborskis, Apolinaras; Zemaitiene, Nida; Värnik, Airi

2013-01-01

Suicide is a leading cause of death among youth. In the year 2002, Lithuania had the 2nd, Luxembourg the 5th, and Estonia the 9th highest suicide rates among 15- to 19-year-olds across 90 countries worldwide. Suicidal ideation is a significant precursor to suicide. To report on the prevalence of and associations between suicidal ideation, smoking, alcohol consumption, physical fighting, bullying, and communication with parents among 15-year-old schoolchildren. The survey analyzes data from the 2005/2006 HBSC study from Estonia, Lithuania, and Luxembourg (N = 4,954). The risk factors were calculated through multinomial logistic regression analyses. The overall prevalence of suicidal ideation in the preceding year was 17%. Suicidal thoughts were associated with communication difficulties with parents (OR from 2.0 to 4.6) and other risk factors, especially multiple risks (OR for 4-5 concurrent risk factors from 4.5 to 13.6). Parent-child communication had a significant mediating effect by decreasing the odds for suicidality and multiple risks. The prevalence estimates were obtained by self-reports. The causal relationships need further investigation. The risk factors studied, particularly multiple risks, were associated with higher odds for suicidal ideation. Good parent-child communication is a significant resource for decreasing suicidal ideation among adolescents.

Lithium levels in the public drinking water supply and risk of suicide: A pilot study.

PubMed

Liaugaudaite, Vilma; Mickuviene, Narseta; Raskauskiene, Nijole; Naginiene, Rima; Sher, Leo

2017-09-01

Suicide is a major public health concern affecting both the society and family life. There are data indicating that higher level lithium intake with drinking water is associated with lower suicide rate. This pilot study examined the relationship between lithium levels in drinking water and suicide rates in Lithuania. Twenty-two samples from public drinking water systems were taken in 9 cities of Lithuania. The lithium concentration in these samples was determined by inductively coupled plasma mass spectrometry (ICP-MS). The suicide data were obtained from the Lithuania Database of Health Indicators, and comprised all registered suicides across all ages and gender within the 5-year period from 2009 to 2013. The study demonstrated an inverse correlation between levels of lithium (log natural transformed), number of women for 1000 men and standardized mortality rate for suicide among total study population. After adjusting for confounder (the number of women for 1000 men), the lithium level remained statistically significant in men, but not in women. Our study suggested that higher levels of lithium in public drinking water are associated with lower suicide rates in men. It might have a protective effect on the risk of suicide in men. Copyright © 2017 The Authors. Published by Elsevier GmbH.. All rights reserved.

Leisure-time physical inactivity and psychological distress in female-dominated occupations in Lithuania.

PubMed

Malinauskiene, Vilija; Malinauskas, Romualdas; Malinauskas, Mindaugas

2017-12-27

Poor mental health, manifesting as psychological distress, has become a leading problem recently; therefore, determining associated factors is important, especially in female-dominated occupations, as women are more prone to psychological distress than men, in part due to demands of both professional and domestic tasks. The objective of the present study was to investigate associations between leisure-time physical inactivity and psychological distress, accounting for the possible relation of psychosocial factors at work (job demands, job control, social support at work, workplace bullying) and life events in representative samples of family physicians, internal medicine department nurses and secondary-school teachers in Lithuania. In total, 323 family physicians, 748 internal medicine department nurses and 517 secondary-school teachers were interviewed during 2012-2014 in Lithuania. Godin leisure-time exercise, Goldberg General Health, Job content, and Negative acts questionnaires were administered. Logistic regression was used. A high proportion of family physicians, nurses and teachers were physically inactive during leisure. Leisure-time physical inactivity was strongly associated with psychological distress, adjusting for age, workplace bullying, job demands, job control, social support at work and traumatic life events in all three female-dominated occupations. Efforts to increase leisure-time physical activity level in medical occupations could be beneficial.

Laboratory medicine education in Lithuania.

PubMed

Kucinskiene, Zita Ausrele; Bartlingas, Jonas

2011-01-01

In Lithuania there are two types of specialists working in medical laboratories and having a university degree: laboratory medicine physicians and medical biologists. Both types of specialists are officially being recognized and regulated by the Ministry of Health of Lithuania. Laboratory medicine physicians become specialists in laboratory medicine after an accredited 4-year multidisciplinary residency study program in Laboratory Medicine. The residency program curriculum for laboratory medicine physicians is presented. On December 9, 2009 the Equivalence of Standards for medical specialists was accepted and Lithuanian medical specialists in Clinical Chemistry and Laboratory Medicine can now apply for EC4 registration. Medical biologists become specialists in laboratory medicine after an accredited 2-year master degree multidisciplinary study program in Medical Biology, consisting of 80 credits. Various postgraduate advanced training courses for the continuous education of specialists in laboratory medicine were first introduced in 1966. Today it covers 1-2-week courses in different subspecialties of laboratory medicine. They are obligatory for laboratory medicine physicians for the renewal of their license. It is not compulsory for medical biologists to participate in these courses. The Centre of Laboratory Diagnostics represents a place for the synthesis and application of the basic sciences, the performance of research in various fields of laboratory medicine, as well as performance of thousands of procedures daily and provision of specific teaching programs.

[Changes in hemodialysis adequacy in Lithuania during 1999-2005].

PubMed

Ziginskiene, Edita; Kuzminskis, Vytautas; Sileikiene, Elvyra; Tamosaitis, Algirdas; Sirevicius, Virgilijus

2007-01-01

Despite the improvement of hemodialysis technique, mortality of chronic hemodialysis patients remains quite high. It considerably depends on dialysis adequacy. The aim of the study was to evaluate the adequacy of hemodialysis procedure and its changes in Lithuania during 1999-2005. Between 1999 and 2005 in December, all hemodialysis centers in Lithuania were annually visited, and data on the type of hemodialysis, duration of hemodialysis (hours per week), single-pool Kt/V were collected from all hemodialysis patients. The percentage of patients on bicarbonate hemodialysis sharply increased from 57.9% in 1999 to 100% in 2001 (P<0.001), and the duration of hemodialysis procedure increased (67.3% of hemodialysis patients were dialyzed 12 and more hours per week in 2005 vs. 41.3% in 1999, P<0.001). The percentage of patients who were dialyzed three times per week increased from 51% in 1999 to 77% in 2005 (P<0.001). The mean Kt/V was 0.81+/-0.53 in 1999, but it increased to 1.21+/-0.27 in 2005 (P<0.001). More than half (54%) of all hemodialysis patients in 2005 had Kt/V > or =1.2 vs. more than one-third (36%) in 1999 (P<0.001). The mean Kt/V of patients who were on dialysis three times per week was 1.25+/-0.6; two times per week, 1.30+/-0.8; and one time per week, 1.27+/-0.26 in 2003. In 2005, the results were 1.21+/-0.27, 1.22+/-0.26, and 1.16+/-0.29, respectively (P>0.05). CONCLUSIONS. 1. The improvement of the quality of hemodialysis was observed in Lithuania during 1999-2005: a) from 2001, patients received only bicarbonate hemodialysis; b) weekly duration of hemodialysis increased; c) Kt/V improved. 2. Despite the improvement of hemodialysis quality, it is not optimal yet and is associated with insufficient duration of hemodialysis.

The results of nucleic acid testing in remunerated and non-remunerated blood donors in Lithuania

PubMed Central

Kalibatas, Vytenis; Kalibatienė, Lina

2014-01-01

Background In Lithuania, governmentally covered remuneration for whole blood donations prevails. Donors may choose to accept or reject the remuneration. The purpose of this study was to compare the rate of nucleic acid testing (NAT) discriminatory-positive markers for human immunodeficiency virus-1 (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV) in seronegative, first-time and repeat, remunerated and non-remunerated donations at the National Blood Centre in Lithuania during the period from 2005 to 2010. Materials and methods All seronegative whole blood and blood component donations were individually analysed by NAT for HIV-1, HBV and HCV. Only discriminatory-positive NAT were classified. The prevalence of discriminatory-positive NAT per 100,000 donations in the donor groups and the odds ratios comparing the remunerated and non-remunerated donations were determined. Results Significant differences were observed for HBV NAT results: 47.42 and 26.29 per 100,000 remunerated first-time and repeat donations, respectively, compared to 10.6 and 3.58 per 100,000 non-remunerated first-time and repeat, seronegative donations, respectively. The differences were also significant for HCV NAT results: 47.42 and 51.99 for remunerated first-time and repeat donations, respectively, compared to 2.12 and 0 per 100,000 non-remunerated first-time and repeat, seronegative donations, respectively. No seronegative, discriminatory-positive NAT HIV case was found. The odds of discriminatory HBV and HCV NAT positive results were statistically significantly higher for both first-time and repeat remunerated donations compared to first-time and repeat non-remunerated donations. Discussion First-time and repeat remunerated seronegative donations were associated with a statistically significantly higher prevalence and odds for discriminatory-positive HBV and HCV NAT results compared to first-time and repeat non-remunerated donations at the National Blood Centre in Lithuania. PMID:24120587

Familial determinants of current smoking among adolescents of Lithuania: a cross-sectional survey 2014.

PubMed

Zaborskis, Apolinaras; Sirvyte, Dainora

2015-09-14

Understanding the role of the family in shaping adolescent health risk behaviours has recently been given increased attention. This study investigated association between current smoking and a range of familial factors in a representative sample of Lithuanian adolescents. Study subjects (N = 3696) were adolescents aged 13- and 15-years from the schools in Lithuania who were surveyed in Spring 2014 according to the methodology of the cross-national Health Behaviour in School-aged Children (HBSC). A standard HBSC international questionnaire was translated into Lithuanian and used anonymously to obtain information about current smoking patterns and family life (family structure, quality of communication in family, parental monitoring, bonding, parenting style, family time, etc.). Logistic regression was used to assess association between smoking and familial variables. The prevalence of current smoking was 16.5 % (20.8 % in boys and 11.9 % in girls; P < 0.001). Adjusting for gender, age and family affluence, adolescents from non-intact families were significantly more likely to be current smokers (OR = 2.10; 95 % CI: 1.74-2.54) compared with intact families. Five independent familial factors were significantly related to increased risk for adolescent smoking: low maternal monitoring (OR = 2.79; 95 % CI: 1.98-3.92), low satisfaction with family relationships (OR = 1.89; 95 % CI: 1.27-2.83), low school-related parental support (OR = 1.40; 95 % CI: 1.01-1.95), easy communication with the father (OR = 0.56; 95 % CI: 0.38-0.80) and often use of electronic media for communication with parents (OR = 0.66; 95 % CI: 0.50-0.88). The last two determinants showed an inverse effect than it was hypothesized. Higher prevalence of smoking among adolescents of Lithuania is associated with a non- intact family structure as well as weaker parental support and bonding. Family life practices are critical components to be incorporated in prevention and intervention programs for adolescent smoking in Lithuania.

Are advance directives helpful for good end of life decision making: a cross sectional survey of health professionals.

PubMed

Peicius, Eimantas; Blazeviciene, Aurelija; Kaminskas, Raimondas

2017-06-05

This paper joins the debate over changes in the role of health professionals when applying advance directives to manage the decision-making process at the end of life care. Issues in relation to advance directives occur in clinical units in Lithuania; however, it remains one of the few countries in the European Union (EU) where the discussion on advance directives is not included in the health-care policy-making agenda. To encourage the discussion of advance directives, a study was designed to examine health professionals' understanding and preferences related to advance directives. In addition, the study sought to explore the views of health care professionals of the application of Advance Directives (AD) in clinical practice in Lithuania. A cross-sectional survey was conducted by interviewing 478 health professionals based at major health care centers in Kaunas district, Lithuania. The design of the study included the use of a questionnaire developed for this study and validated by a pilot study. The collected data were analyzed using standard descriptive statistical methods. The analysis of knowledge about AD revealed some statistically significant differences when comparing the respondents' profession and gender. The analysis also indicated key emerging themes among respondents including tranquility of mind, the longest possible life expectancy and freedom of choice. Further, the study findings revealed that more than half of the study participants preferred to express their will while alive by using advance directives. The study findings revealed a low level of knowledge on advance directives among health professionals. Most health professionals agreed that AD's improved end-of-life decision making while the majority of physicians appreciated AD as the best tool for sharing responsibilities in clinical practice in Lithuania. More physicians than nurses preferred the presence of advance directives to support their decision making in end-of-life situations.

Prevalence and burden of headache disorders in Lithuania and their public-health and policy implications: a population-based study within the Eurolight Project.

PubMed

Rastenytė, Daiva; Mickevičienė, Dalia; Stovner, Lars Jacob; Thomas, Hallie; Andrée, Colette; Steiner, Timothy J

2017-12-01

The Eurolight project assessed the impact of headache disorders in ten EU countries, using the same structured questionnaire but varying sampling methods. In Lithuania, sample selection employed methods in line with consensus recommendations for population-based burden-of-headache studies. The survey was cross-sectional. We identified, from the Residents' Register Service, a sample of inhabitants of Kaunas city and surrounding Kaunas region reflecting age (in the range 18-65 years), gender and rural/urban distributions of Lithuania. Medical students called unannounced at their homes and conducted face-to-face interviews employing a structured questionnaire. Of 1137 people in the pre-identified sample, 573 (male 237 [41.4%], female 336 [58.6%]; mean age 40.9 ± 13.8 years) completed interviews (participation proportion: 50.4%). Gender-adjusted 1-year prevalences were: any headache 74.7%; migraine 18.8%; tension-type headache (TTH) 42.2%; all headache on ≥15 days/month 8.6%; probable medication-overuse headache (pMOH) 3.2%. Migraine (OR: 3.6) and pMOH (OR: 2.9) were associated with female gender. All headache types except TTH were associated with significantly diminished quality of life. Migraine caused a mean 4.5% loss in paid worktime per affected male and 3.5% per affected female. Lost per-person times due to TTH were much less, but to pMOH and other headache on ≥15 days/month much higher. Among the entire workforce, lost productivity to migraine was estimated at 0.7%, to TTH 0.3% and to pMOH or other headache on ≥15 days/month 0.5%. The total of 1.5% may translate directly into lost GDP. Alternative calculations based on headache yesterday (with little recall error) produced, for all headache, a corroborating 1.7%. Similar losses from household work would also drain the nation's economy. Our findings were comparable to those from earlier studies using similar methods in Russia and Georgia. The multiple burdens from headache in Lithuania indicate substantial ill-health and unmet need for health care. The heavy burdens on individuals are matched by heavy economic burden. Of particular concern is the high prevalence of headache on ≥15 days/month, seen also in Russia and Georgia. Health policy in Lithuania must heed WHO's advice that effective treatment of headache, clearly desirable for its health benefits, is also expected to be cost-saving.

Prevalence and familial predictors of suicidal behaviour among adolescents in Lithuania: a cross-sectional survey 2014.

PubMed

Zaborskis, Apolinaras; Sirvyte, Dainora; Zemaitiene, Nida

2016-07-12

In the past decades Lithuania has been experiencing a very high suicide rate among young people and there are scarce data on the role of the family in shaping these people suicidal behaviour. This study investigated the prevalence of suicidal ideation and attempts, as well as their association with a range of familial factors in a representative sample of Lithuanian adolescents. Study subjects (N = 3572) were adolescents aged 13- and 15-years from the schools in Lithuania who were surveyed in Spring 2014 according to the methodology of the cross-national Health Behaviour in School-aged Children (HBSC). A standard HBSC international questionnaire was translated into Lithuanian and used anonymously to obtain information about suicidal behaviour (stopped doing activities, considered suicide, planned suicide, and suicide attempts) and family life (family structure, quality of communication in family, parental monitoring and bonding, parenting style, family time, etc.). Logistic regression was used to assess association between suicidal behaviours and familial variables. Forty three percents of surveyed adolescents reported presence of emotions that stopped doing activities during the last 12 months, 23.8 % seriously considered attempting suicide, 13.7 % made a suicide plan, 13.2 % attempted suicide, and 4.1 % needed treatment because of suicide attempt in the previous year. Adolescents from non-intact families reported more suicidal ideation (OR ranged from 1.32 to 1.35, P < 0.05) and more suicide attempts (OR = 1.70, 95 % CI 1.38-2.09, P < 0.001). Among adolescents from intact families, some manisfestations of suicidal behaviour were significantly associated with low satisfaction in family relationships, low father's and mother's emotional support, low mother's monitoring, low school-related parental support, authoritarian-repressive father's parenting style and permissive-neglectful mother's parenting style, but rare family time together and rare electronic media communication with parents were inversely associated with suicidal behaviour. The boys, 15-year-olds and adolescents who indicated often activities together with their families were more likely than their counterparts to report suicide attempts treated by a doctor or nurse. The young people of Lithuania are at particular risk for suicides. A non-intact family structure and weak family functioning are significant predictors of suicidal ideation and attempts among adolescents of Lithuania. It is essential to consider family life practices in planning intervention programs for prevention of suicides among adolescents.

Conservation of geo- and -biodiversity in Lithuania: are there conflicts?

NASA Astrophysics Data System (ADS)

Skridlaite, Grazina; Motiejunaite, Jurga

2014-05-01

Lithuanian surface is sculptured by more than five glaciers, which retreated c. 10 000 years ago. After the ice sheets melted in Lithuania, Latvia and Poland, and other neighbouring countries, they left numerous erratic boulders and boulder fields. Hundreds of single boulders and boulder fields are declared as natural monuments in Lithuania and other countries and are variably protected. Tens of single boulders and boulder fields are included into the Geosites database at the Lithuanian Geological Survey. Rapid weather changes in Lithuania cause the weathering of erratic boulders. However, the fastest erosion is by overgrowing cryptogams: lichenized and non-lichenized fungi, algae, cyanobacteria and bryophytes. Lichens are among the first colonizers of rock surfaces, and their impact on stonework heritage is rather well documented. Hard rocks (e.g. granites) are weathering considerably slower than soft or relatively soft sandstones, dolomites or marbles; however serious impact is visible on stones with inscriptions, drawings and open surfaces of the protected nature monuments. Lichens gradually cover whole boulder surfaces obscuring their geological value and contributing to the surface weathering in Lithuania and neighbouring countries where numerous protected stony nature monuments occur. The 73 of the 723 species of lichenized and allied fungi in Lithuania are confined to hard acid rocks. Eight of these acid rock-dwelling species are included in the Lithuanian Red Data Book, some of them have high threat category or are thought to be extinct now. There is no conservation conflict between the red-listed saxicolous lichens and their substrate where the species are confined to wild boulder meadows. Here lichens and their boulder substrate suffer from excessive growth and overshadowing from surrounding vascular plants, also from pollution which change stone surface properties and induce encroachment of more aggressive species than the usual slow-growing acid rock communities. The main conservation conflict occurs when the solitary boulder monuments or open boulder expositions (e.g. V. Intas' Museum of Boulders in Mosedis, the Geology Museum in Vievis) are concerned. These expositions are supposed to serve a basis for geological science and education; however they are almost completely overgrown. Attempts to clean the boulders were met by general public and some scientists rather negatively and caused several conflicts. A wave of negative opinions appeared in media after the second largest boulder Puntukas was cleaned by compressed water streams. Several problems are concerned. First of all, both chemical and mechanical cleaning not only will remove lichens and other cryptogams, but may be damaging to a boulder or to environment and wildlife. The measures should be taken with utmost care, and lichen species as well as stone surfaces are to be examined before applying any treatment. Another problem is to convince general public, caretakers and scientists that the overgrown stone surfaces should be cleaned. Some botanists, foresters, environmental people would prefer to let the nature to do its work and to cover stony surfaces with vegetation. Therefore, in conflict cases, expert opinions, both botanical and geological should be addressed. This is a contribution to the Open Access Centre activities

Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci

PubMed Central

Zubair, Niha; Luis Ambite, Jose; Bush, William S.; Kichaev, Gleb; Lu, Yingchang; Manichaikul, Ani; Sheu, Wayne H-H.; Absher, Devin; Assimes, Themistocles L.; Bielinski, Suzette J.; Bottinger, Erwin P.; Buzkova, Petra; Chuang, Lee-Ming; Chung, Ren-Hua; Cochran, Barbara; Dumitrescu, Logan; Gottesman, Omri; Haessler, Jeffrey W.; Haiman, Christopher; Heiss, Gerardo; Hsiung, Chao A.; Hung, Yi-Jen; Hwu, Chii-Min; Juang, Jyh-Ming J.; Le Marchand, Loic; Lee, I-Te; Lee, Wen-Jane; Lin, Li-An; Lin, Danyu; Lin, Shih-Yi; Mackey, Rachel H.; Martin, Lisa W.; Pasaniuc, Bogdan; Peters, Ulrike; Predazzi, Irene; Quertermous, Thomas; Reiner, Alex P.; Robinson, Jennifer; Rotter, Jerome I.; Ryckman, Kelli K.; Schreiner, Pamela J.; Stahl, Eli; Tao, Ran; Tsai, Michael Y.; Waite, Lindsay L.; Wang, Tzung-Dau; Buyske, Steven; Ida Chen, Yii-Der; Cheng, Iona; Crawford, Dana C.; Loos, Ruth J.F.; Rich, Stephen S.; Fornage, Myriam; North, Kari E.; Kooperberg, Charles; Carty, Cara L.

2016-01-01

Abstract Genome-wide association studies have identified over 150 loci associated with lipid traits, however, no large-scale studies exist for Hispanics and other minority populations. Additionally, the genetic architecture of lipid-influencing loci remains largely unknown. We performed one of the most racially/ethnically diverse fine-mapping genetic studies of HDL-C, LDL-C, and triglycerides to-date using SNPs on the MetaboChip array on 54,119 individuals: 21,304 African Americans, 19,829 Hispanic Americans, 12,456 Asians, and 530 American Indians. The majority of signals found in these groups generalize to European Americans. While we uncovered signals unique to racial/ethnic populations, we also observed systematically consistent lipid associations across these groups. In African Americans, we identified three novel signals associated with HDL-C (LPL, APOA5, LCAT) and two associated with LDL-C (ABCG8, DHODH). In addition, using this population, we refined the location for 16 out of the 58 known MetaboChip lipid loci. These results can guide tailored screening efforts, reveal population-specific responses to lipid-lowering medications, and aid in the development of new targeted drug therapies. PMID:28426890

"In my opinion, work would be in first place and family in second": young women's imagined gender-work relations in post-Soviet Lithuania.

PubMed

Reiter, Herwig

2010-01-01

This article explores young women's orientation to work and motherhood in the post-communist context of radical socio-economic transformation in Europe. Based on a qualitative-explorative study into meanings of work and unemployment among young people in post-Soviet Lithuania, the paper introduces an empirically grounded classification of imagined gender-work arrangements. The single patterns of the classification are based on the three configurations of work and motherhood, work and partnership, and work and provision. The findings inform the reconstruction of the 'landscape' of imagined gendered adulthoods in Europe as well as the analysis of emerging gender relations under conditions of rapid social change.

Epiphytic lichen community dynamics in deciduous forests around a phosphorus fertiliser factory in Central Lithuania.

PubMed

Motiejūnaite, Jurga

2007-03-01

The detailed dynamics of epiphytic lichen communities were observed while studying permanent quadrats in the zone of influence of a phosphorus fertiliser factory in central Lithuania. The most significant changes were induced by several factors: changes in macroenvironment (increase of illumination), bark scaling, succession processes, individual growth characteristics of the community members, and influence of fungal infection and invertebrate grazing. None of these changes could be directly linked with air pollution. These observations have shown that in conditions of more or less stable pollution, epiphytic community dynamics should be evaluated with care, the best indicators of the characteristics of the communities being species richness and presence/absence and abundance of indicator (nitrophilous or acidophilous) species.

New European community strategy for health and safety: the elephant in the room.

PubMed

Woolfson, Charles; Calite, Dace

2007-01-01

Although Lithuania has comprehensive health and safety legislation in line with EU requirements, on a range of general health and occupational health and safety (OHS) indicators, it is a poor performer. Survey data suggest that the norm for work in Lithuania is based on a regime of intensification without a participative working environment in which employees have a voice in safety management. Although European-style legislative reforms appear to be having no measurable effects on CHS performance in post-communist New Member States, the EU OHS strategy for 2007-2012 fails to take account of the deteriorated working environments in these states, suggesting that prospects for harmonization of working environment standards in the enlarged Europe may recede with eastward expansion.

Impact of Gender, Ethnicity, Year in School, Social Economic Status, and State Standardized Assessment Scores on Student Content Knowledge Achievement when Using Vee Maps as a Formative Assessment Tool

ERIC Educational Resources Information Center

Thoron, Andrew C.; Myers, Brian E.

2011-01-01

The National Research Council has recognized the challenge of assessing laboratory investigation and called for the investigation of assessments that are proven through sound research-based studies. The Vee map provides a framework that allows the learners to conceptualize their previous knowledge as they develop success in meaningful learning…

Type 2 diabetes mellitus: distribution of genetic markers in Kazakh population

PubMed Central

Sikhayeva, Nurgul; Talzhanov, Yerkebulan; Iskakova, Aisha; Dzharmukhanov, Jarkyn; Nugmanova, Raushan; Zholdybaeva, Elena; Ramanculov, Erlan

2018-01-01

Background Ethnic differences exist in the frequencies of genetic variations that contribute to the risk of common disease. This study aimed to analyse the distribution of several genes, previously associated with susceptibility to type 2 diabetes and obesity-related phenotypes, in a Kazakh population. Methods A total of 966 individuals belonging to the Kazakh ethnicity were recruited from an outpatient clinic. We genotyped 41 common single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes in other ethnic groups and 31 of these were in Hardy–Weinberg equilibrium. The obtained allele frequencies were further compared to publicly available data from other ethnic populations. Allele frequencies for other (compared) populations were pooled from the haplotype map (HapMap) database. Principal component analysis (PCA), cluster analysis, and multidimensional scaling (MDS) were used for the analysis of genetic relationship between the populations. Results Comparative analysis of allele frequencies of the studied SNPs showed significant differentiation among the studied populations. The Kazakh population was grouped with Asian populations according to the cluster analysis and with the Caucasian populations according to PCA. According to MDS, results of the current study show that the Kazakh population holds an intermediate position between Caucasian and Asian populations. Conclusion A high percentage of population differentiation was observed between Kazakh and world populations. The Kazakh population was clustered with Caucasian populations, and this result may indicate a significant Caucasian component in the Kazakh gene pool. PMID:29551892

Minerals yearbook: Mineral industries of Europe and central Eurasia. Volume 3. 1992 international review

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-01-01

Volume III, Minerals Yearbook -- International Review contains the latest available mineral data on more than 175 foreign countries and discusses the importance of minerals to the economies of these nations. Since the 1989 International Review, the volume has been presented as six reports. The report presents the Mineral Industries of Europe and Central Eurasia. The report incorporates location maps, industry structure tables, and an outlook section previously incorporated in the authors' Minerals Perspectives Series quinquennial regional books, which are being discontinued. This section of the Minerals Yearbook reviews the minerals industries of 45 countries: the 12 nations of themore » European Community (EC); 6 of the 7 nations of the European Free Trade Association (EFTA); Malta; the 11 Eastern European economies in transition (Albania, Bosnia and Hercegovina, Bulgaria, Croatia, Czechoslovakia, Hungary, Macedonia, Poland, Romania, Serbia and Montenegro, and Slovenia); and the countries of Central Eurasia (Armenia, Azerbaijan, Belarus, Estonia, Georgia, Kazakhstan, Kyrgystan, Latvia, Lithuania, Moldova, Russia, Tajikistan, Turkmenistan, Ukraine, and Uzbekistan).« less

Citizen empowerment in the domestic waste policy development in Lithuania

NASA Astrophysics Data System (ADS)

Stasiukynas, Andrius; Survila, Arvydas; Smalskys, Vainius

2017-04-01

Lithuania offers an interesting case of lagging in terms of domestic waste recycling in the European context. Despite the adoption of all relevant EU regulation, including a pricing system, which is designed to be more conducive for recycling. One important group of policy instruments which in the application of which Lithuania needs to improve, is public participation in environmental governance. The objective of this study is to relate the means of public participation and the decision-making on waste management and recycling outcomes. The study consisted of two stages. Stage one: key decision-making public agencies responsible for policy formulation and implementation of domestic waste management were identified. Later, an analysis of public available documentation covering decision-making in these institutions was conducted with the aim to measure the level of citizen engagement. Stage two: agency managers and staff responsible for citizen engagement were interviewed with the goal of evaluating their attitudes. Attitudes of officials are a crucial for a successful citizen engagement. The results showed that officials recognized very little the value of citizen engagement. They perceived contribution as an the creation of additional challenges to be tackled with, rather than help to lower service delivery costs and improve policy effectiveness. This renders the government with a depleted number of options of improving domestic waste management to "top-down" measures and imposition of financial incentives or costs.

An inter-country comparison of unofficial payments: results of a health sector social audit in the Baltic States

PubMed Central

Cockcroft, Anne; Andersson, Neil; Paredes-Solís, Sergio; Caldwell, Dawn; Mitchell, Steve; Milne, Deborah; Merhi, Serge; Roche, Melissa; Konceviciute, Elena; Ledogar, Robert J

2008-01-01

Background Cross-country comparisons of unofficial payments in the health sector are sparse. In 2002 we conducted a social audit of the health sector of the three Baltic States. Methods Some 10,320 household interviews from a stratified, last-stage-random, sample of 30 clusters per country, together with institutional reviews, produced preliminary results. Separate focus groups of service users, nurses and doctors interpreted these findings. Stakeholder workshops in each country discussed the survey and focus group results. Results Nearly one half of the respondents did not consider unofficial payments to health workers to be corruption, yet one half (Estonia 43%, Latvia 45%, Lithuania 64%) thought the level of corruption in government health services was high. Very few (Estonia 1%, Latvia 3%, Lithuania 8%) admitted to making unofficial payments in their last contact with the services. Around 14% of household members across the three countries gave gifts in their last contact with government services. Conclusion This social audit allowed comparison of perceptions, attitudes and experience regarding unofficial payments in the health services of the three Baltic States. Estonia showed least corruption. Latvia was in the middle. Lithuania evidenced the most unofficial payments, the greatest mistrust towards the system. These findings can serve as a baseline for interventions, and to compare each country's approach to health service reform in relation to unofficial payments. PMID:18208604

The Nation and the Family: The Impact of National Identification and Perceived Importance of Family Values on Homophobic Attitudes in Lithuania and Scotland.

PubMed

Wakefield, Juliet R H; Kalinauskaite, Monika; Hopkins, Nick

The meanings attached to the nation can be consequential for group members' attitudes and beliefs. We examined how national identity definition can influence the extent of individuals' homophobia with 159 Lithuanian and 176 Scottish university students who completed a questionnaire which measured their national identification, homophobia, and the extent to which they felt traditional family values were central to their nation's identity. Consistent with nation-wide differences in the significance given to the family, Lithuanian participants perceived family values to be more important for their national identity and expressed higher levels of homophobia than did Scottish participants. Moreover, the relationship between level of national identification and homophobia was stronger in Lithuania than in Scotland. Analyses revealed that the perceived importance of family values helped explain the difference between homophobia levels in Lithuania and Scotland. In both sites we found an indirect effect of national identification on homophobia via the perceived importance of family values, but this effect was significantly stronger for Lithuanian participants. These findings illustrate the ways in which identification with the nation is relevant to attitudes concerning sexuality, and how this varies according to national context. Our work indicates that LGBT rights campaigns should be informed by the knowledge that homophobia may be perpetuated by national valorisation of the family.

Characteristics of dental attendance among Lithuanian middle-aged university employees.

PubMed

Sakalauskiene, Zana; Maciulskiene, Vita; Vehkalahti, Miira M; Kubilius, Ricardas; Murtomaa, Heikki

2009-01-01

This study aimed to evaluate and describe the dental attendance patterns and to characterize the factors that encourage preventive dental visits among 35- to 44-year-old university employees in Lithuania. A questionnaire survey was conducted anonymously among the 35- to 44-year-old employees (n=862) of four universities in Lithuania in 2005. The response rate was 64% (n=553). Data on their most recent dental visit, habitual dental attendance, and self-reported dental health were collected. Gender, marital status, education, and income levels served as background factors. Of the respondents, 79% were women, and 82% held a university degree. Of all the respondents, 75% reported having their most recent dental visit within the previous 12 months; 19% indicated a preventive check-up as the reason for it (15%--self-decided visit and 4%--dentist's recall). The most common treatments received were fillings (75%), scaling and cleaning (28%), and endodontic treatment (22%). Analysis of the data about habitual dental attendance showed that preventive check-up as the main reason for attendance was more commonly reported by women (OR=1.7), among those who indicated having lost fewer teeth (OR=1.5), reported higher incomes (OR=1.4), and who indicated a shorter time interval since their most recent dental visit (OR=1.3). Dental problem seems to be a dominant reason for dental attendance in Lithuania where both dentists' and patients' behavior weakly reflects preventive orientation.

An inter-country comparison of unofficial payments: results of a health sector social audit in the Baltic States.

PubMed

Cockcroft, Anne; Andersson, Neil; Paredes-Solís, Sergio; Caldwell, Dawn; Mitchell, Steve; Milne, Deborah; Merhi, Serge; Roche, Melissa; Konceviciute, Elena; Ledogar, Robert J

2008-01-21

Cross-country comparisons of unofficial payments in the health sector are sparse. In 2002 we conducted a social audit of the health sector of the three Baltic States. Some 10,320 household interviews from a stratified, last-stage-random, sample of 30 clusters per country, together with institutional reviews, produced preliminary results. Separate focus groups of service users, nurses and doctors interpreted these findings. Stakeholder workshops in each country discussed the survey and focus group results. Nearly one half of the respondents did not consider unofficial payments to health workers to be corruption, yet one half (Estonia 43%, Latvia 45%, Lithuania 64%) thought the level of corruption in government health services was high. Very few (Estonia 1%, Latvia 3%, Lithuania 8%) admitted to making unofficial payments in their last contact with the services. Around 14% of household members across the three countries gave gifts in their last contact with government services. This social audit allowed comparison of perceptions, attitudes and experience regarding unofficial payments in the health services of the three Baltic States. Estonia showed least corruption. Latvia was in the middle. Lithuania evidenced the most unofficial payments, the greatest mistrust towards the system. These findings can serve as a baseline for interventions, and to compare each country's approach to health service reform in relation to unofficial payments.

Occupational characteristics of respiratory cancer patients exposed to asbestos in Lithuania

NASA Astrophysics Data System (ADS)

Everatt, R. Petrauskaitdot e.; Smolianskiedot n, G.; Tossavainen, A.; Cicdot enas, S.; Jankauskas, R.

2009-02-01

Objective: To assess characteristics of asbestos exposure in respiratory cancer patients in Lithuania. Methods. Information on occupational exposure to asbestos was collected by personal interviews and occupational characteristics were evaluated among 183 lung cancer and mesothelioma patients with cumulative asbestos exposure >=0.01 fibre years hospitalized at the Institute of Oncology, Vilnius. Additionally, some results of workplace air measurements were reviewed. Results. Cases with estimated cumulative exposure >=5 fibre years had worked mainly in the construction industry (49%), installation and maintenance (13%), foundry and metal products manufacturing (6%), heating trades and boilerhouses (6%) as fitters/maintenance technicians, construction workers, welders, electricians or foremen. Typical asbestos materials used by the patients were asbestos powder, asbestos cement sheets and pipes, asbestos cord, brake and clutch linings. Patients were exposed to asbestos when insulating boilers, furnaces, pipes in power stations, industrial facilities, ships, locomotives, buildings, while covering and repairing roofs, at the asbestos cement plant or unloading asbestos products. Most patients with estimated cumulative exposure of >=0.01-4.9 fibre years worked as lorry, bus or tractor drivers and motor vehicle mechanics. In 2002-2007 workplace air asbestos concentrations exceeded the limit value of 0.1 f/cm3 in 11 samples out of 208 measurements. Conclusion. The results of this study indicate that since the 1960s occupational exposure to chrysotile asbestos was extensive in Lithuania.

Suicide mortality trends in young people aged 15 to 19 years in Lithuania.

PubMed

Strukcinskiene, B; Andersson, R; Janson, S

2011-11-01

This paper considers the suicide mortality trends from 1990-2009 in young people aged 15 to 19 years in Lithuania. Suicide and injury mortality data, plus mortality data from all causes, were used to compare the trend lines. Suicide mortality rate in young people aged 15-19 years and in all population showed a rising trend from 1990, and then a decreasing trend from 2002 year. This trend was significant exclusively in boys. When comparing suicide deaths as a percentage of injury deaths and of all deaths in the age group 15-19 years, rising trends for boys were evident, whilst in girls, there was no evidence of change. In Lithuania, from early 1990s, the frequency of suicide increased amongst adults and young people aged 15-19 years. After 2002, a decrease in deaths by suicide was observed both for the whole population and for young people aged 15-19 years. The rise and fall was obvious for boys. The reasons for different trends may have been influenced by the political and socioeconomic instability in the 1990-2002 period, and the socioeconomic stability, together with active preventive measures, from 2002. Although the consumption of modern Selective serotonin reuptake inhibitors (SSRIs) increased during the same time, suicide mortality was again high during the economic crisis in 2008-2009. © 2011 The Author(s)/Acta Paediatrica © 2011 Foundation Acta Paediatrica.

Holocene malacofauna in calcareous deposits of Dūkšta site near Maišiagala in Lithuania

NASA Astrophysics Data System (ADS)

Sanko, Aleksander; Gaigalas, Algirdas; Rudnickaitė, Eugenija; Melešytė, Monika

2008-01-01

The paper contains results of new investigations in Lithuania of the first occurrences of terrestrial molluscs in calcareous tufa (travertine), carbonate content and radiocarbon dating. Terrestrial fossil molluscs (35 taxa) prevail in the mollusc fauna, while freshwater species are much more rare (6 taxa). The Dūkšta terrestrial mollusc fauna embraces a complex of thermophiles including such forest species as Acicula polita (Hartmann), Acanthinula aculeata (Müller), Aegopinella cf. pura (Alder), Bulgaria cana (Held) and Discus cf. rotundatus (Müller), as well as mainly South European Carychium tridentatum (Risso) and mainly West European Vertigo moulinsiana (Dupuy). The radiocarbon age of the sediments was found to correspond to the end of the Atlantic climatic period and the beginning of the Subboreal.

EGFR mutation incidence in non-small-cell lung cancer of adenocarcinoma histology: a systematic review and global map by ethnicity (mutMapII)

PubMed Central

Midha, Anita; Dearden, Simon; McCormack, Rose

2015-01-01

Mutations in the epidermal growth factor receptor (EGFR) gene are commonly observed in non-small-cell lung cancer (NSCLC), particularly in tumors of adenocarcinoma (ADC) histology (NSCLC/ADC). Robust data exist regarding the prevalence of EGFR mutations in Western and Asian patients with NSCLC/ADC, yet there is a lack of data for patients of other ethnicities. This review collated available data with the aim of creating a complete, global picture of EGFR mutation frequency in patients with NSCLC/ADC by ethnicity. Worldwide literature reporting EGFR mutation frequency in patients with NSCLC/ADC was reviewed, to create a map of the world populated with EGFR mutation frequency by country (a ‘global EGFR mutMap’). A total of 151 worldwide studies (n=33162 patients with NSCLC/ADC, of which 9749 patients had EGFR mutation-positive NSCLC/ADC) were included. There was substantial variation in EGFR mutation frequency between studies, even when grouped by geographic region or individual country. As expected, the Asia-Pacific NSCLC/ADC subgroup had the highest EGFR mutation frequency (47% [5958/12819; 87 studies; range 20%-76%]) and the lowest EGFR mutation frequency occurred in the Oceania NSCLC/ADC subgroup (12% [69/570; 4 studies; range 7%-36%]); however, comparisons between regions were limited due to the varying sizes of the patient populations studied. In all regional (geographic) subgroups where data were available, EGFR mutation frequency in NSCLC/ADC was higher in women compared with men, and in never-compared with ever-smokers. This review provides the foundation for a global map of EGFR mutation frequency in patients with NSCLC/ADC. The substantial lack of data from several large geographic regions of the world, notably Africa, the Middle East, Central Asia, and Central and South America, highlights a potential lack of routine mutation testing and the need for further investigations in these regions. PMID:26609494

Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci.

PubMed

Zubair, Niha; Graff, Mariaelisa; Luis Ambite, Jose; Bush, William S; Kichaev, Gleb; Lu, Yingchang; Manichaikul, Ani; Sheu, Wayne H-H; Absher, Devin; Assimes, Themistocles L; Bielinski, Suzette J; Bottinger, Erwin P; Buzkova, Petra; Chuang, Lee-Ming; Chung, Ren-Hua; Cochran, Barbara; Dumitrescu, Logan; Gottesman, Omri; Haessler, Jeffrey W; Haiman, Christopher; Heiss, Gerardo; Hsiung, Chao A; Hung, Yi-Jen; Hwu, Chii-Min; Juang, Jyh-Ming J; Le Marchand, Loic; Lee, I-Te; Lee, Wen-Jane; Lin, Li-An; Lin, Danyu; Lin, Shih-Yi; Mackey, Rachel H; Martin, Lisa W; Pasaniuc, Bogdan; Peters, Ulrike; Predazzi, Irene; Quertermous, Thomas; Reiner, Alex P; Robinson, Jennifer; Rotter, Jerome I; Ryckman, Kelli K; Schreiner, Pamela J; Stahl, Eli; Tao, Ran; Tsai, Michael Y; Waite, Lindsay L; Wang, Tzung-Dau; Buyske, Steven; Ida Chen, Yii-Der; Cheng, Iona; Crawford, Dana C; Loos, Ruth J F; Rich, Stephen S; Fornage, Myriam; North, Kari E; Kooperberg, Charles; Carty, Cara L

2016-12-15

Genome-wide association studies have identified over 150 loci associated with lipid traits, however, no large-scale studies exist for Hispanics and other minority populations. Additionally, the genetic architecture of lipid-influencing loci remains largely unknown. We performed one of the most racially/ethnically diverse fine-mapping genetic studies of HDL-C, LDL-C, and triglycerides to-date using SNPs on the MetaboChip array on 54,119 individuals: 21,304 African Americans, 19,829 Hispanic Americans, 12,456 Asians, and 530 American Indians. The majority of signals found in these groups generalize to European Americans. While we uncovered signals unique to racial/ethnic populations, we also observed systematically consistent lipid associations across these groups. In African Americans, we identified three novel signals associated with HDL-C (LPL, APOA5, LCAT) and two associated with LDL-C (ABCG8, DHODH). In addition, using this population, we refined the location for 16 out of the 58 known MetaboChip lipid loci. These results can guide tailored screening efforts, reveal population-specific responses to lipid-lowering medications, and aid in the development of new targeted drug therapies. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

2 CFR 176.90 - Non-application to acquisitions covered under international agreements.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., Bulgaria, Canada, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hong Kong..., Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Latvia, Lithuania, Luxembourg...

Prevalence of C282Y, H63D, and S65C mutations in hereditary HFE-hemochromatosis gene in Lithuanian population.

PubMed

Kucinskas, Laimutis; Juzenas, Simonas; Sventoraityte, Jurgita; Cedaviciute, Ruta; Vitkauskiene, Astra; Kalibatas, Vytenis; Kondrackiene, Jurate; Kupcinskas, Limas

2012-04-01

HFE-hemochromatosis is a common autosomal recessive disease caused by HFE gene mutations and characterized as iron overload and failure of different organs. The aim of this study was to determine the prevalence of C282Y (c.845 G>A), H63D (c.187 C>G), and S65C (c.193A>T) alleles of HFE gene in the Lithuanian population. One thousand and eleven healthy blood donors of Lithuanian nationality were examined in four different ethnic Lithuanian regions to determine HFE gene alleles and genotype frequencies. The samples of DNA were analyzed for the presence of restriction fragment length polymorphism and validated by DNA sequencing. Among 1,011 blood donors tested, the frequency of C282Y, H63D, and S65C alleles were 2.6%, 15.9%, and 1.9%, respectively. One third of the tested subjects (n = 336) had at least one of the C282Y or H63D HFE gene mutations. The screening of Lithuanian blood donors has detected 13 (1.3%) subjects with a genotype C282Y/C282Y or C282Y/H63D responsible for the development of HFE-hemochromatosis. The prevalence of C282Y mutation was significantly higher among the inhabitants of Zemaitija (Somogitia) at the Baltic Sea area (5.9%) in comparison to the regions of continental part of Lithuania (2.4% in Dzukija, 2.3% in Aukstaitija, and 2% in Suvalkija, p < 0.05). These data support the hypothesis that the p.C282Y mutation originated from Scandinavia and spread with the Vikings along the Baltic Sea coast. The first epidemiological investigation of HFE gene mutations in ethnic Lithuanians showed that the frequencies of H63D, C282Y, and S65C of HFE gene alleles are similar to the other North-Eastern Europeans, especially in the Baltic region (Estonia, Latvia), Poland, and part of Russia (Moscow region).

Polymorphic admixture typing in human ethnic populations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dean, M.; Stephens, J.C.; Boaze, R.

1994-10-01

A panel of 257 RFLP loci was selected on the basis of high heterozygosity in Caucasian DNA surveys and equivalent spacing throughout the human genome. Probes from each locus were used in a Southern blot survey of allele frequency distribution for four human ethnic groups: Caucasian, African American, Asian (Chinese), and American Indian (Cheyenne). Nearly all RFLP loci were polymorphic in each group, albeit with a broad range of differing allele frequencies ({delta}). The distribution of frequency differences ({delta} values) was used for three purposes: (1) to provide estimates for genetic distance (differentiation) among these ethnic groups, (2) to revisitmore » with a large data set the proportion of human genetic variation attributable to differentiation within ethnic groups, and (3) to identify loci with high {delta} values between recently admixed populations of use in mapping by admixture linkage disequilibrium (MALD). Although most markers display significant allele frequency differences between ethnic groups, the overall genetic distances between ethnic groups were small (.066-.098), and <10% of the measured overall molecular genetic diversity in these human samples can be attributed to {open_quotes}racial{close_quotes} differentiation. The median {delta} values for pairwise comparisons between groups fell between .15 and .20, permitting identification of highly informative RFLP loci for MALD disease association studies. 43 refs., 5 figs., 5 tabs.« less

Purpose in life as a resource for increasing comfort with ethnic diversity.

PubMed

Burrow, Anthony L; Stanley, Maclen; Sumner, Rachel; Hill, Patrick L

2014-11-01

Emerging demographic trends signal that White Americans will soon relinquish their majority status. As Whites' acclimation to an increasingly diverse society is poised to figure prominently in their adjustment, identifying sources of greater comfort with diversity is important. Three studies (N = 519) revealed evidence that purpose in life bolsters comfort with ethnic diversity among White adults. Specifically, dispositional purpose was positively related to diversity attitudes and attenuated feelings of threat resulting from viewing demographic projections of greater diversity. In addition, when primed experimentally, purpose attenuated participants' preferences for living in an ethnically homogeneous-White city, relative to a more diverse city when shown maps displaying ethno-demographic information. These effects persisted after controlling for positive affect and perceived connections to ethnic out-groups, suggesting the robust influence of purpose. Potential benefits of situating purpose as a unique resource for navigating an increasingly diverse society are discussed. © 2014 by the Society for Personality and Social Psychology, Inc.

Reports on Cancer - Cancer Statistics

Cancer.gov

Interactive tools for access to statistics for a cancer site by gender, race, ethnicity, calendar year, age, state, county, stage, and histology. Statistics include incidence, mortality, prevalence, cost, risk factors, behaviors, tobacco use, and policies and are presented as graphs, tables, or maps.

[Parallels in development of hemodialysis service and kidney transplantations in Lithuania during 1996-2005].

PubMed

Ziginskiene, Edita; Kuzminskis, Vytautas; Bumblyte, Inga Arūne; Santockiene, Lina; Dalinkeviciene, Egle; Kardauskaite, Zydrūne; Uogintaite, Jurgita; Motiejūnaite, Agne; Butautas, Ernestas; Vainauskas, Vaclovas; Macius, Kazimieras; Sakalauskiene, Marija; Steckis, Ricardas; Gaupsiene, Egle; Urbanaviciene, Jūrate; Labutiene, Vilma

2007-01-01

The aim of our study was to evaluate the changes in hemodialysis service, main demographic characteristics of hemodialysis patients in Lithuania during 1996-2005, and their correlation with the number of recipients on the kidney waiting list. During the study period, we annually visited all hemodialysis centers in Lithuania and collected data about all hemodialysis patients. There was a sharp increase in the number of hemodialysis centers (from 17 to 43), hemodialysis stations (from 25 to 100 per million population, P<0.001), hemodialysis patients (from 60 to 312 per million population, P<0.001), and new hemodialysis patients (from 54.3 to 95 per million population, P<0.01). The mean age of hemodialysis patients increased from 47.2+/-16.1 years in 1996 to 58.8+/-15.6 years in 2005 (P<0.001). Hemodialysis population became older. The percentage of patients aged more than 60 years increased from 22.8% to 53.2% (P<0.001) and aged more than 70 years from 5.4% to 24.4% (P<0.001). The frequency of chronic glomerulonephritis as underlying disease of end-stage renal disease decreased from 54.5% in 1996 to 21.1% in 2005 (P<0.001). There was an increase in the percentage of patients in whom end-stage renal disease was caused by diabetic (from 7.1% to 19.2%, P<0.01) and hypertensive nephropathies (from 3.1% to 13.9%, P<0.05) and chronic pyelonephritis (from 11.2% to 17.9%, P<0.01). The percentage of recipients on the kidney waiting list decreased from 71.4% in 1996 to 21.1% in 2005. In summary, during the last 9 years, hemodialysis service in Lithuania significantly expanded. The number of hemodialysis patients was continuously rising with predominance of diabetic, hypertensive, and elderly patients. Diabetic nephropathy, chronic glomerulonephritis, and pyelonephritis were the main underlying diseases of end-stage renal disease in hemodialysis patients in 2005. The percentage of recipients on the kidney waiting list decreased probably because of the rise in the number of elderly patients and patients with diabetes mellitus in Lithuanian hemodialysis population.

Value priorities and their relations with quality of life in the Baby Boomer generation of Lithuanian nurses: a cross-sectional survey.

PubMed

Blazeviciene, Aurelija; Jakusovaite, Irayda

2007-11-08

The understanding of the values of nurses is especially important, since nurses constitute 80% of workforce in the healthcare system in Lithuania. In addition to that, nursing is one of the major constituents of healthcare. The aim of this study was to determine what values predominate in the cohort of Baby Boomer nurses, and to evaluate the relation of these values with quality of life using M. Rokeach's terminal and instrumental values scale. M.Rokeach distinguished terminal values (such as world peace, wisdom, and happiness), which are preferred end-states of existence, and instrumental values (such as responsibility and cooperation), which are preferred modes of conduct. We performed a representative anonymous questionnaire-based inquiry of nurses working in regional hospitals of Lithuania. The nurses who participated in the study were distributed into four work cohorts: the Veterans, the Baby Boomers, the Generation Xers, and the Generation Nexters. The majority of the nurses belonged to the Baby Boomers and the Generation Xers cohorts. Since in Lithuania, like in the whole Europe, the representatives of the Baby Boomers generation are predominating among working people, we selected this cohort (N = 387) for the analysis. The survey data was processed using the SPSS statistical software package The main values in life were family security, tranquility, and a sense of accomplishment. However, such values as true friendship, equality, and pleasurable and leisured life were seen as rather insignificant. The most important instrumental values were honesty, skillfulness, and responsibility. Our study showed a statistically significant (albeit weak) correlation between the QOL and terminal values such as the sense of accomplishment, tranquility, equality, and pleasure, as well as the instrumental value - obedience. We detected a statistically significant relationship between good QOL and satisfaction with oneself, relationships with the surrounding people, and friends' support. The findings of our study showed that, although Lithuania was under a totalitarian regime for 50 years, both the terminal and the instrumental values of the Baby Boomers generation are very similar to those of the same generation in other countries.

Value priorities and their relations with quality of life in the Baby Boomer generation of Lithuanian nurses: a cross-sectional survey

PubMed Central

Blazeviciene, Aurelija; Jakusovaite, Irayda

2007-01-01

Background The understanding of the values of nurses is especially important, since nurses constitute 80% of workforce in the healthcare system in Lithuania. In addition to that, nursing is one of the major constituents of healthcare. The aim of this study was to determine what values predominate in the cohort of Baby Boomer nurses, and to evaluate the relation of these values with quality of life using M. Rokeach's terminal and instrumental values scale. M.Rokeach distinguished terminal values (such as world peace, wisdom, and happiness), which are preferred end-states of existence, and instrumental values (such as responsibility and cooperation), which are preferred modes of conduct. Methods We performed a representative anonymous questionnaire-based inquiry of nurses working in regional hospitals of Lithuania. The nurses who participated in the study were distributed into four work cohorts: the Veterans, the Baby Boomers, the Generation Xers, and the Generation Nexters. The majority of the nurses belonged to the Baby Boomers and the Generation Xers cohorts. Since in Lithuania, like in the whole Europe, the representatives of the Baby Boomers generation are predominating among working people, we selected this cohort (N = 387) for the analysis. The survey data was processed using the SPSS statistical software package Results The main values in life were family security, tranquility, and a sense of accomplishment. However, such values as true friendship, equality, and pleasurable and leisured life were seen as rather insignificant. The most important instrumental values were honesty, skillfulness, and responsibility. Our study showed a statistically significant (albeit weak) correlation between the QOL and terminal values such as the sense of accomplishment, tranquility, equality, and pleasure, as well as the instrumental value – obedience. We detected a statistically significant relationship between good QOL and satisfaction with oneself, relationships with the surrounding people, and friends' support. Conclusion The findings of our study showed that, although Lithuania was under a totalitarian regime for 50 years, both the terminal and the instrumental values of the Baby Boomers generation are very similar to those of the same generation in other countries. PMID:17996067

Type 2 Diabetes Risk Alleles Demonstrate Extreme Directional Differentiation among Human Populations, Compared to Other Diseases

PubMed Central

Chen, Rong; Corona, Erik; Sikora, Martin; Dudley, Joel T.; Morgan, Alex A.; Moreno-Estrada, Andres; Nilsen, Geoffrey B.; Ruau, David; Lincoln, Stephen E.; Bustamante, Carlos D.; Butte, Atul J.

2012-01-01

Many disease-susceptible SNPs exhibit significant disparity in ancestral and derived allele frequencies across worldwide populations. While previous studies have examined population differentiation of alleles at specific SNPs, global ethnic patterns of ensembles of disease risk alleles across human diseases are unexamined. To examine these patterns, we manually curated ethnic disease association data from 5,065 papers on human genetic studies representing 1,495 diseases, recording the precise risk alleles and their measured population frequencies and estimated effect sizes. We systematically compared the population frequencies of cross-ethnic risk alleles for each disease across 1,397 individuals from 11 HapMap populations, 1,064 individuals from 53 HGDP populations, and 49 individuals with whole-genome sequences from 10 populations. Type 2 diabetes (T2D) demonstrated extreme directional differentiation of risk allele frequencies across human populations, compared with null distributions of European-frequency matched control genomic alleles and risk alleles for other diseases. Most T2D risk alleles share a consistent pattern of decreasing frequencies along human migration into East Asia. Furthermore, we show that these patterns contribute to disparities in predicted genetic risk across 1,397 HapMap individuals, T2D genetic risk being consistently higher for individuals in the African populations and lower in the Asian populations, irrespective of the ethnicity considered in the initial discovery of risk alleles. We observed a similar pattern in the distribution of T2D Genetic Risk Scores, which are associated with an increased risk of developing diabetes in the Diabetes Prevention Program cohort, for the same individuals. This disparity may be attributable to the promotion of energy storage and usage appropriate to environments and inconsistent energy intake. Our results indicate that the differential frequencies of T2D risk alleles may contribute to the observed disparity in T2D incidence rates across ethnic populations. PMID:22511877

Ethnic differences in arterial stiffness the Helius study.

PubMed

Snijder, Marieke B; Stronks, Karien; Agyemang, Charles; Busschers, Wim B; Peters, Ron J; van den Born, Bert-Jan H

2015-07-15

Well-known ethnic differences in cardiovascular risk exist, which may be explained by ethnic differences in arterial stiffness. Our aim was to assess ethnic differences in arterial stiffness, to explore whether these differences are accounted for by conventional cardiovascular risk factors, and study whether they differ across age. Cross-sectional data of 1797 Dutch, 1846 South-Asian Surinamese, 1840 African Surinamese, and 1673 Ghanaian participants of the observational HELIUS study (aged 18-70 years) were used. Arterial stiffness was assessed by duplicate pulse wave velocity (PWV) measurements using the Arteriograph system. Linear regression showed that South-Asian Surinamese had higher PWVs as compared with Dutch (age-adjusted mean difference (95% CI) was 0.55 (0.39-0.70) m/s in men and 0.82 (0.63-1.01) m/s in women). These differences were largely, but not completely, explained by conventional risk factors (particularly age and MAP). These ethnic differences were not found at young age (<35 years). African Surinamese and Ghanaians had higher PWVs as compared with Dutch across the entire age range (ranging from 0.22 (0.06-0.39) m/s in African Surinamese men to 1.07 (0.89-1.26) m/s in Ghanaian women), but these differences disappeared or reversed after adjustment for risk factors. PWV levels paralleled the well-known ethnic differences in cardiovascular risk. After adjustment for cardiovascular risk factors, however, these ethnic differences in PWV largely disappear. Together with the absence of ethnic differences in PWV at young age, our results support the hypothesis that higher PWV in South-Asian and African ethnic groups develops due to higher exposure to cardiovascular risk factors. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

7 CFR 319.59-3 - Articles prohibited importation pending risk evaluation.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., Kazakhstan, Kyrgyzstan, Latvia, Libya, Lithuania, Moldova, Morocco, Nepal, North Korea, Oman, Pakistan... Korea, Ukraine, Uzbekistan, and Venezuela. [70 FR 8231, Feb. 18, 2005, as amended at 70 FR 71212, Nov...

7 CFR 319.59-3 - Articles prohibited importation pending risk evaluation.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., Kazakhstan, Kyrgyzstan, Latvia, Libya, Lithuania, Moldova, Morocco, Nepal, North Korea, Oman, Pakistan... Korea, Ukraine, Uzbekistan, and Venezuela. [70 FR 8231, Feb. 18, 2005, as amended at 70 FR 71212, Nov...

7 CFR 319.59-3 - Articles prohibited importation pending risk evaluation.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., Kazakhstan, Kyrgyzstan, Latvia, Libya, Lithuania, Moldova, Morocco, Nepal, North Korea, Oman, Pakistan... Korea, Ukraine, Uzbekistan, and Venezuela. [70 FR 8231, Feb. 18, 2005, as amended at 70 FR 71212, Nov...

Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations

PubMed Central

Okada, Yukinori; Kim, Kwangwoo; Han, Buhm; Pillai, Nisha E.; Ong, Rick T.-H.; Saw, Woei-Yuh; Luo, Ma; Jiang, Lei; Yin, Jian; Bang, So-Young; Lee, Hye-Soon; Brown, Matthew A.; Bae, Sang-Cheol; Xu, Huji; Teo, Yik-Ying; de Bakker, Paul I.W.; Raychaudhuri, Soumya

2014-01-01

Previous studies have emphasized ethnically heterogeneous human leukocyte antigen (HLA) classical allele associations to rheumatoid arthritis (RA) risk. We fine-mapped RA risk alleles within the major histocompatibility complex (MHC) in 2782 seropositive RA cases and 4315 controls of Asian descent. We applied imputation to determine genotypes for eight class I and II HLA genes to Asian populations for the first time using a newly constructed pan-Asian reference panel. First, we empirically measured high imputation accuracy in Asian samples. Then we observed the most significant association in HLA-DRβ1 at amino acid position 13, located outside the classical shared epitope (Pomnibus = 6.9 × 10−135). The individual residues at position 13 have relative effects that are consistent with published effects in European populations (His > Phe > Arg > Tyr ≅ Gly > Ser)—but the observed effects in Asians are generally smaller. Applying stepwise conditional analysis, we identified additional independent associations at positions 57 (conditional Pomnibus = 2.2 × 10−33) and 74 (conditional Pomnibus = 1.1 × 10−8). Outside of HLA-DRβ1, we observed independent effects for amino acid polymorphisms within HLA-B (Asp9, conditional P = 3.8 × 10−6) and HLA-DPβ1 (Phe9, conditional P = 3.0 × 10−5) concordant with European populations. Our trans-ethnic HLA fine-mapping study reveals that (i) a common set of amino acid residues confer shared effects in European and Asian populations and (ii) these same effects can explain ethnically heterogeneous classical allelic associations (e.g. HLA-DRB1*09:01) due to allele frequency differences between populations. Our study illustrates the value of high-resolution imputation for fine-mapping causal variants in the MHC. PMID:25070946

Curonian Spit, Lithuania and Russia

NASA Technical Reports Server (NTRS)

2007-01-01

The Curonian Spit in Lithuania and the Russian Federation was inscribed as a UNESCO World Heritage Site in 2000. Human habitation of this elongated sand dune peninsula, 98 km long and 0.4-4 km wide, dates back to prehistoric times. Throughout this period it has been threatened by the natural forces of wind and waves. Its survival to the present day has been made possible only as a result of ceaseless human efforts to combat erosion through stabilization and reforestation projects.

The image covers an area of 55.8 x 109.5 km, was acquired on July 25, 2006, and is located near 55.3 degrees north latitude, 20.9 degrees east longitude.

The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

Ecodevelopmental contexts for preventing type 2 diabetes in Latino and other racial/ethnic minority populations

PubMed Central

Shaibi, Gabriel Q.; Boehm-Smith, Edna

2009-01-01

Diabetes is the sixth leading cause of death in the United States and it is now cited along with obesity as a global epidemic. Significant racial/ethnic disparities exist in the prevalence of diabetes within the US, with racial and ethnic minorities disproportionately affected by type 2 diabetes and its complications. Racial/ethnic and socioeconomic factors influence the development and course of diabetes at multiple levels, including genetic, individual, familial, community and national. From an ecodevelopmental perspective, cultural variables assessed at one level (e.g., family level dietary practices) may interact with other types of variables examined at other levels (e.g., the availability of healthy foods within a low-income neighborhood), thus prompting the need for a clear analysis of these systemic relationships as they may increase risks for disease. Therefore, the need exists for models that aid in “mapping out” these relationships. A more explicit conceptualization of such multi-level relationships would aid in the design of culturally relevant interventions that aim to maximize effectiveness when applied with Latinos and other racial/ethnic minority groups. This paper presents an expanded ecodevelopmental model intended to serve as a tool to aid in the design of multi-level diabetes prevention interventions for application with racial/ethnic minority populations. This discussion focuses primarily on risk factors and prevention intervention in Latino populations, although with implications for other racial/ethnic minority populations that are also at high risk for type 2 diabetes. PMID:19101788

The relationship of female physical attractiveness to body fatness.

PubMed

Wang, Guanlin; Djafarian, Kurosh; Egedigwe, Chima A; El Hamdouchi, Asmaa; Ojiambo, Robert; Ramuth, Harris; Wallner-Liebmann, Sandra Johanna; Lackner, Sonja; Diouf, Adama; Sauciuvenaite, Justina; Hambly, Catherine; Vaanholt, Lobke M; Faries, Mark D; Speakman, John R

2015-01-01

Aspects of the female body may be attractive because they signal evolutionary fitness. Greater body fatness might reflect greater potential to survive famines, but individuals carrying larger fat stores may have poor health and lower fertility in non-famine conditions. A mathematical statistical model using epidemiological data linking fatness to fitness traits, predicted a peaked relationship between fatness and attractiveness (maximum at body mass index (BMI) = 22.8 to 24.8 depending on ethnicity and assumptions). Participants from three Caucasian populations (Austria, Lithuania and the UK), three Asian populations (China, Iran and Mauritius) and four African populations (Kenya, Morocco, Nigeria and Senegal) rated attractiveness of a series of female images varying in fatness (BMI) and waist to hip ratio (WHR). There was an inverse linear relationship between physical attractiveness and body fatness or BMI in all populations. Lower body fat was more attractive, down to at least BMI = 19. There was no peak in the relationship over the range we studied in any population. WHR was a significant independent but less important factor, which was more important (greater r (2)) in African populations. Predictions based on the fitness model were not supported. Raters appeared to use body fat percentage (BF%) and BMI as markers of age. The covariance of BF% and BMI with age indicates that the role of body fatness alone, as a marker of attractiveness, has been overestimated.

The relationship of female physical attractiveness to body fatness

PubMed Central

Wang, Guanlin; Djafarian, Kurosh; Egedigwe, Chima A.; El Hamdouchi, Asmaa; Ojiambo, Robert; Ramuth, Harris; Wallner-Liebmann, Sandra Johanna; Lackner, Sonja; Diouf, Adama; Sauciuvenaite, Justina; Hambly, Catherine; Vaanholt, Lobke M.; Faries, Mark D.

2015-01-01

Aspects of the female body may be attractive because they signal evolutionary fitness. Greater body fatness might reflect greater potential to survive famines, but individuals carrying larger fat stores may have poor health and lower fertility in non-famine conditions. A mathematical statistical model using epidemiological data linking fatness to fitness traits, predicted a peaked relationship between fatness and attractiveness (maximum at body mass index (BMI) = 22.8 to 24.8 depending on ethnicity and assumptions). Participants from three Caucasian populations (Austria, Lithuania and the UK), three Asian populations (China, Iran and Mauritius) and four African populations (Kenya, Morocco, Nigeria and Senegal) rated attractiveness of a series of female images varying in fatness (BMI) and waist to hip ratio (WHR). There was an inverse linear relationship between physical attractiveness and body fatness or BMI in all populations. Lower body fat was more attractive, down to at least BMI = 19. There was no peak in the relationship over the range we studied in any population. WHR was a significant independent but less important factor, which was more important (greater r2) in African populations. Predictions based on the fitness model were not supported. Raters appeared to use body fat percentage (BF%) and BMI as markers of age. The covariance of BF% and BMI with age indicates that the role of body fatness alone, as a marker of attractiveness, has been overestimated. PMID:26336638

Estimation of reactive surface area using a combined method of laboratory analyses and digital image processing

NASA Astrophysics Data System (ADS)

Ma, Jin; Kong, Xiang-Zhao; Saar, Martin O.

2017-04-01

Fluid-rock interactions play an important role in the engineering processes such as chemical stimulation of enhanced geothermal systems and carbon capture, utilization, and storage. However, these interactions highly depend on the accessible reactive surface area of the minerals that are generally poorly constrained for natural geologic samples. In particular, quantifying surface area of each reacting mineral within whole rock samples is challenging due to the heterogeneous distribution of minerals and pore space. In this study, detailed laboratory analyses were performed on sandstone samples from deep geothermal sites in Lithuania. We measure specific surface area of whole rock samples using a gas adsorption method (so-called B.E.T.) with N2 at a temperature of 77.3K. We also quantify their porosity and pore size distribution by a Helium gas pycnometer and a Hg porosimetry, respectively. Rock compositions are determined by a combination of X-ray fluorescence (XRF) and quantitative scanning electron microscopy (SEM) - Energy-dispersive X-ray spectroscopy (EDS), which are later geometrically mapped on images of two-dimensional SEM- Backscattered electrons (BSE) with a resolution of 1.2 μm and three-dimensional micro-CT with a resolution of 10.3 μm to produce a digital mineral map for further constraining the accessibility of reactive minerals. Moreover, we attempt to link the whole rock porosity, pore size distribution, and B.E.T. specific surface area with the digital mineral maps. We anticipate these necessary analyses to provide in-depth understanding of fluid sample chemistry from later hydrothermal reactive flow-through experiments on whole rock samples at elevated pressure and temperature.

Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained

PubMed Central

Wu, Ying; Waite, Lindsay L.; Jackson, Anne U.; Sheu, Wayne H-H.; Buyske, Steven; Absher, Devin; Arnett, Donna K.; Boerwinkle, Eric; Bonnycastle, Lori L.; Carty, Cara L.; Cheng, Iona; Cochran, Barbara; Croteau-Chonka, Damien C.; Dumitrescu, Logan; Eaton, Charles B.; Franceschini, Nora; Guo, Xiuqing; Henderson, Brian E.; Hindorff, Lucia A.; Kim, Eric; Kinnunen, Leena; Komulainen, Pirjo; Lee, Wen-Jane; Le Marchand, Loic; Lin, Yi; Lindström, Jaana; Lingaas-Holmen, Oddgeir; Mitchell, Sabrina L.; Narisu, Narisu; Robinson, Jennifer G.; Schumacher, Fred; Stančáková, Alena; Sundvall, Jouko; Sung, Yun-Ju; Swift, Amy J.; Wang, Wen-Chang; Wilkens, Lynne; Wilsgaard, Tom; Young, Alicia M.; Adair, Linda S.; Ballantyne, Christie M.; Bůžková, Petra; Chakravarti, Aravinda; Collins, Francis S.; Duggan, David; Feranil, Alan B.; Ho, Low-Tone; Hung, Yi-Jen; Hunt, Steven C.; Hveem, Kristian; Juang, Jyh-Ming J.; Kesäniemi, Antero Y.; Kuusisto, Johanna; Laakso, Markku; Lakka, Timo A.; Lee, I-Te; Leppert, Mark F.; Matise, Tara C.; Moilanen, Leena; Njølstad, Inger; Peters, Ulrike; Quertermous, Thomas; Rauramaa, Rainer; Rotter, Jerome I.; Saramies, Jouko; Tuomilehto, Jaakko; Uusitupa, Matti; Wang, Tzung-Dau; Mohlke, Karen L.

2013-01-01

Genome-wide association studies (GWAS) have identified ∼100 loci associated with blood lipid levels, but much of the trait heritability remains unexplained, and at most loci the identities of the trait-influencing variants remain unknown. We conducted a trans-ethnic fine-mapping study at 18, 22, and 18 GWAS loci on the Metabochip for their association with triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C), respectively, in individuals of African American (n = 6,832), East Asian (n = 9,449), and European (n = 10,829) ancestry. We aimed to identify the variants with strongest association at each locus, identify additional and population-specific signals, refine association signals, and assess the relative significance of previously described functional variants. Among the 58 loci, 33 exhibited evidence of association at P<1×10−4 in at least one ancestry group. Sequential conditional analyses revealed that ten, nine, and four loci in African Americans, Europeans, and East Asians, respectively, exhibited two or more signals. At these loci, accounting for all signals led to a 1.3- to 1.8-fold increase in the explained phenotypic variance compared to the strongest signals. Distinct signals across ancestry groups were identified at PCSK9 and APOA5. Trans-ethnic analyses narrowed the signals to smaller sets of variants at GCKR, PPP1R3B, ABO, LCAT, and ABCA1. Of 27 variants reported previously to have functional effects, 74% exhibited the strongest association at the respective signal. In conclusion, trans-ethnic high-density genotyping and analysis confirm the presence of allelic heterogeneity, allow the identification of population-specific variants, and limit the number of candidate SNPs for functional studies. PMID:23555291

Admixture mapping of serum vitamin D and parathyroid hormone concentrations in the African American-Diabetes Heart Study

PubMed Central

Palmer, Nicholette D.; Divers, Jasmin; Lu, Lingyi; Register, Thomas C.; Carr, J. Jeffrey; Hicks, Pamela J.; Smith, S. Carrie; Xu, Jianzhao; Judd, Suzanne E.; Irvin, Marguerite R.; Gutierrez, Orlando M.; Bowden, Donald W.; Wagenknecht, Lynne E.; Langefeld, Carl D.; Freedman, Barry I.

2016-01-01

Vitamin D and intact parathyroid hormone (iPTH) concentrations differ between individuals of African and European descent and may play a role in observed racial differences in bone mineral density (BMD). These findings suggest that mapping by admixture linkage disequilibrium (MALD) may be informative for identifying genetic variants contributing to these ethnic disparities. Admixture mapping was performed for serum 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D, vitamin D-binding protein (VDBP), bioavailable vitamin D, and iPTH concentrations and computed tomography measured thoracic and lumbar vertebral volumetric BMD in 552 unrelated African Americans with type 2 diabetes from the African American-Diabetes Heart Study. Genotyping was performed using a custom Illumina ancestry informative marker (AIM) panel. For each AIM, the probability of inheriting 0, 1, or 2 copies of a European-derived allele was determined. Non-parametric linkage analysis was performed by testing for association between each AIM using these probabilities among phenotypes, accounting for global ancestry, age, and gender. Fine-mapping of MALD peaks was facilitated by genome-wide association study (GWAS) data. VDBP levels were significantly linked in proximity to the protein coding locus (rs7689609, LOD=11.05). Two loci exhibited significant linkage signals for 1,25-dihydroxyvitamin D on 13q21.2 (rs1622710, LOD=3.20) and 12q13.2 (rs11171526, LOD=3.10). iPTH was significantly linked on 9q31.3 (rs7854368, LOD=3.14). Fine-mapping with GWAS data revealed significant known (rs7041 with VDBP, P=1.38×10−82) and novel (rs12741813 and rs10863774 with VDBP, P<6.43×10−5) loci with plausible biological roles. Admixture mapping in combination with fine-mapping has focused efforts to identify loci contributing to ethnic differences in vitamin D-related traits. PMID:27032714

Inside Rural Pennsylvania: A Statistical Profile.

ERIC Educational Resources Information Center

Center for Rural Pennsylvania, Harrisburg.

Graphs, data tables, maps, and written descriptions give a statistical overview of rural Pennsylvania. A section on rural demographics covers population changes, racial and ethnic makeup, age cohorts, and families and income. Pennsylvania's rural population, the nation's largest, has increased more than its urban population since 1950, with the…

Cancer incidence in the workers cohort of textile manufacturing factory in Alytus, Lithuania.

PubMed

Kuzmickiene, Irena; Didziapetris, Remigijus; Stukonis, Mecys

2004-02-01

Altogether 14,650 workers employed at least for 1 year a the textile factory in Alytus, Lithuania, were included in the cohort and followed during the period from 1978 to 1997. The standardized incidence ratio (SIR) for men was 1.28. The incidence of esophagus cancer was significant higher (SIR 3.42). It increased only slightly for lung (SIR 1.35). In the women cohort, SIR was 1.05. However, there was a significant increase of the incidence of gallbladder cancer (SIR 3.19). Among textile-processing (spinning and weaving departments) women workers, we found elevated total cancer incidence (SIR 1.35), incidence of breast cancer (SIR 1.49), and cervical cancer (SIR 1.82). In this cohort increased SIR values were observed for more than 10 years since first exposure for all cancer (SIR 1.70) and cervical cancer (SIR 2.44).

Learning discriminative features from RGB-D images for gender and ethnicity identification

NASA Astrophysics Data System (ADS)

Azzakhnini, Safaa; Ballihi, Lahoucine; Aboutajdine, Driss

2016-11-01

The development of sophisticated sensor technologies gave rise to an interesting variety of data. With the appearance of affordable devices, such as the Microsoft Kinect, depth-maps and three-dimensional data became easily accessible. This attracted many computer vision researchers seeking to exploit this information in classification and recognition tasks. In this work, the problem of face classification in the context of RGB images and depth information (RGB-D images) is addressed. The purpose of this paper is to study and compare some popular techniques for gender recognition and ethnicity classification to understand how much depth data can improve the quality of recognition. Furthermore, we investigate which combination of face descriptors, feature selection methods, and learning techniques is best suited to better exploit RGB-D images. The experimental results show that depth data improve the recognition accuracy for gender and ethnicity classification applications in many use cases.

Ghettos and enclaves in the cross-place realm: mapping socially bounded spaces across cities.

PubMed

Montgomery, Alesia F

2011-01-01

Since the early Chicago School, urban researchers have used residential proximity to assess contacts within and between racial and ethnic groups. This approach is increasingly limited. Diverse groups use email, social networking sites, instant messaging and mobile phones to communicate across urban zones and distant cities. These practices enable mutual support among far-flung family members and co-ethnics as they engage with an array of institutions throughout their day. Through interviews and observations that include women and men of diverse occupations, races and national origins, the author explores how and why cross-place enclosures of sociality and resources develop. Rather than framing the residential area as the locus of racial/ethnic concentration, the author focuses on cross-place concentrations in the technologically mediated workspace. This study enhances theorization of the structural negotiations, interpersonal pressures and group preferences that produce separate lifeworlds in globalizing cities.

Mapping "Chinese" Christian Schools in Indonesia: Ethnicity, Class and Religion

ERIC Educational Resources Information Center

Hoon, Chang-Yau

2011-01-01

Schools are not "innocent" sites of cultural transmission. They play an active and significant role in transmitting values and inculcating culture. Schools also serve as a site for the maintenance of boundaries and for the construction of identities. Previous studies have recognized the relationship between education and identity.…

Up Against the Glass Ceiling: Culture and Gender in the Workplace.

ERIC Educational Resources Information Center

Cordeiro, Paula A.

1997-01-01

Uses a cultural map exercise to show how culture affects educators' perspectives of gender issues in school administration. Discusses individual cultural identity and the influences of educators' societal/national, regional/linguistic or racial/ethnic, and individual belief cultures. Feminist theory and its premises can help everyone understand…

Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis.

PubMed

Benyamin, Beben; He, Ji; Zhao, Qiongyi; Gratten, Jacob; Garton, Fleur; Leo, Paul J; Liu, Zhijun; Mangelsdorf, Marie; Al-Chalabi, Ammar; Anderson, Lisa; Butler, Timothy J; Chen, Lu; Chen, Xiang-Ding; Cremin, Katie; Deng, Hong-Weng; Devine, Matthew; Edson, Janette; Fifita, Jennifer A; Furlong, Sarah; Han, Ying-Ying; Harris, Jessica; Henders, Anjali K; Jeffree, Rosalind L; Jin, Zi-Bing; Li, Zhongshan; Li, Ting; Li, Mengmeng; Lin, Yong; Liu, Xiaolu; Marshall, Mhairi; McCann, Emily P; Mowry, Bryan J; Ngo, Shyuan T; Pamphlett, Roger; Ran, Shu; Reutens, David C; Rowe, Dominic B; Sachdev, Perminder; Shah, Sonia; Song, Sharon; Tan, Li-Jun; Tang, Lu; van den Berg, Leonard H; van Rheenen, Wouter; Veldink, Jan H; Wallace, Robyn H; Wheeler, Lawrie; Williams, Kelly L; Wu, Jinyu; Wu, Xin; Yang, Jian; Yue, Weihua; Zhang, Zong-Hong; Zhang, Dai; Noakes, Peter G; Blair, Ian P; Henderson, Robert D; McCombe, Pamela A; Visscher, Peter M; Xu, Huji; Bartlett, Perry F; Brown, Matthew A; Wray, Naomi R; Fan, Dongsheng

2017-09-20

Cross-ethnic genetic studies can leverage power from differences in disease epidemiology and population-specific genetic architecture. In particular, the differences in linkage disequilibrium and allele frequency patterns across ethnic groups may increase gene-mapping resolution. Here we use cross-ethnic genetic data in sporadic amyotrophic lateral sclerosis (ALS), an adult-onset, rapidly progressing neurodegenerative disease. We report analyses of novel genome-wide association study data of 1,234 ALS cases and 2,850 controls. We find a significant association of rs10463311 spanning GPX3-TNIP1 with ALS (p = 1.3 × 10 -8 ), with replication support from two independent Australian samples (combined 576 cases and 683 controls, p = 1.7 × 10 -3 ). Both GPX3 and TNIP1 interact with other known ALS genes (SOD1 and OPTN, respectively). In addition, GGNBP2 was identified using gene-based analysis and summary statistics-based Mendelian randomization analysis, although further replication is needed to confirm this result. Our results increase our understanding of genetic aetiology of ALS.Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease. Here, Wray and colleagues identify association of the GPX3-TNIP1 locus with ALS using cross-ethnic meta-analyses.

Self-reported cannabis products and other illicit drugs consumption in older school-age children in Northern Lithuania: a comparison between 2006 and 2012.

PubMed

Miniauskienė, Dalia; Jurgaitienė, Dalia; Strukčinskienė, Birutė

2014-01-01

Cannabis use is widespread among young people in Europe. The aim of this study was to analyze and to compare the associations between the self-reported consumption of cannabis products and other illicit drugs among older schoolchildren in 2006 and in 2012. Two cross-sectional surveys were conducted in 2006 and 2012 in Northern Lithuania. In total 3447 young people aged 17-19 years were investigated (1585 male and 1862 female). For this survey, the ESPAD questionnaire was used. In Northern Lithuania, the schoolchildren aged 17-19 years self-reported that 16.7% in 2006 and 23.9% in 2012 of them tried cannabis products. The consumption of cannabis products in the age group of 17 years increased from 14.9% in 2006 to 21.5% in 2012. The consumption of cannabis together with alcohol increased from 7.6% to 14.3%. Cannabis consumers more often tried amphetamines, heroin, LSD, cocaine, crack, ecstasy, hallucinogenic mushrooms, and injective drugs. In 2012, cannabis consumers girls less than boys used only crack and injective drugs; all other illicit drugs they used the same often as boys. The cannabis products consumption in schoolchildren has increased by 7%. Nearly twofold increase was observed in the consumption of cannabis together with alcohol. Young people who used cannabis products more often tried other illicit drugs. There were no differences by gender in the consumption of illicit drugs among cannabis consumers. Copyright © 2014 Lithuanian University of Health Sciences. Production and hosting by Elsevier Urban & Partner Sp. z o.o. All rights reserved.

The Xpert® MTB/RIF assay in routine diagnosis of pulmonary tuberculosis: A multicentre study in Lithuania.

PubMed

Pimkina, Edita; Zablockis, Rolandas; Nikolayevskyy, Vladyslav; Danila, Edvardas; Davidaviciene, Edita

2015-11-01

Drug-resistant tuberculosis (TB) is an important public health problem in Lithuania with MDR rates in new cases reaching 11% in 2012. Currently available diagnostic tools are not fully adequate for an accurate and rapid result for diagnosis of TB and MDR-TB. To evaluate the performance of Xpert(®) MTB/RIF assay for an early diagnosis of TB and detection of rifampicin (RIF) resistance in routine settings in Lithuania. A total of 833 individual respiratory samples obtained from patients previously treated for TB and MDR-TB contacts were tested using the Xpert MTB/RIF assay. Performance characteristics of the assay for TB and RIF resistance detection were calculated using culture and phenotypical DST results as a gold standard. The overall sensitivity and specificity of the Xpert MTB/RIF assay for TB detection were 93.7% and 91.7%, respectively with the sensitivity for smear-negative specimens reaching 82.5%. Resistance to RIF was detected in 81 (20.7%) primary specimens with no false negative results; there were 4/225 (1.8%) false-positives among strains sensitive to rifampicin. Overall sensitivity and specificity of the molecular assay for detection of RIF resistance calculated against phenotypic DST results were 100% and 98.2%, respectively. Our results demonstrate very good performance of the Xpert MTB/RIF assay for the detection of TB and RIF resistance on primary respiratory specimens. It provides strong evidence that implementation of the assay for routine laboratory diagnosis in high drug-resistance settings may improve and facilitate TB diagnosis. Copyright © 2015 Elsevier Ltd. All rights reserved.

Work related risk factors for musculoskeletal complaints in the spinning industry in Lithuania

PubMed Central

Gamperiene, M.; Stigum, H.

1999-01-01

OBJECTIVES: To describe the prevalence of self reported musculoskeletal complaints in the back, arms or neck, and legs among workers in the spinning industry, and to investigate the relations between these complaints and work related variables. METHODS: An interview based questionnaire survey was carried out in two spinning industry factories in Lithuania. RESULTS: The study group consisted of all workers in production (n = 363). Symptoms of the legs were the musculoskeletal symptom reported most often (61%). Many subjects had arms or neck (55%) or back problems (28%). 20% had experienced pain from all three sites. Almost 25% had had musculoskeletal pain every day and 16% had experienced constant pain during previous year. Packers had the highest risk of arms or neck problems whereas spinners had the highest risk of back or leg problems. Working in a strained posture (bending, work with arms raised up above shoulder level, and repetitive movements of the fingers) was associated with all three complaints. Only arms or neck complaints were associated with age. CONCLUSIONS: Musculoskeletal disorders are a common problem among workers producing gobelin or synthetic thread in Lithuania and working in a strained posture is a risk factor for developing musculoskeletal disorders in three body sites: legs, arms or neck, and back. To better understand the different aspects of physical load as risk factors, a more detailed study of the frequency of postural changes as well as an observation of individually adopted postures would be necessary. This applies to intervention studies in factories of the spinning industry to prevent complaints of the legs and shoulders.   PMID:10474538

The great spruce bark beetle (Dendroctonus micans Kug.) (Coleoptera: Scolytidae) in Lithuania: occurrence, phenology, morphology and communities of associated fungi.

PubMed

Menkis, A; Lynikienė, J; Marčiulynas, A; Gedminas, A; Povilaitienė, A

2017-08-01

We studied the occurrence, morphology and phenology of Dendroctonus micans in Lithuania and the fungi associated with the beetle at different developmental stages. The occurrence of D. micans was assessed in 19 seed orchards (at least 40 years old) of Picea abies (L. Karst.) situated in different parts of the country. Bark beetle phenology was studied in two sites: a seed orchard of P. abies and a plantation of Picea pungens (Engelm.). D. micans morphology was assessed under the dissection microscope using individuals at different developmental stages that were sampled during phenology observations. Communities of fungi associated with D. micans were studied using both fungal culturing methods and direct high-throughput sequencing from D. micans. Results showed that the incidence D. micans was relatively rare and D. micans was mainly detected in central and eastern Lithuania. The life cycle included the following stages: adult, egg, I-V developmental stage larvae and pupa. However, development of D. micans was quicker and its nests larger under the bark of P. pungens than of P. abies, indicating the effect of the host species. Fungal culturing and direct high-throughput sequencing revealed that D. micans associated fungi communities were species rich and dominated by yeasts from a class Saccharomycetes. In total, 319 fungal taxa were sequenced, among which Peterozyma toletana (37.5% of all fungal sequences), Yamadazyma scolyti (30.0%) and Kuraishia capsulate (17.7%) were the most common. Plant pathogens and blue stain fungi were also detected suggesting their potentially negative effects to both tree health and timber quality.

What health domains and items are important to patients with knee osteoarthritis? A focus group study in a multiethnic urban Asian population.

PubMed

Xie, F; Li, S-C; Fong, K-Y; Lo, N-N; Yeo, S-J; Yang, K-Y; Thumboo, J

2006-03-01

To determine important health-related quality of life (HRQoL) domains and items within each domain affected by knee osteoarthritis (OA), identify ethnic variations in the importance of these domains and items among three ethnic groups, and determine how identified domains and items mapped onto selected OA-specific HRQoL instruments. Focus groups were conducted among subjects with knee OA stratified by gender, ethnicity, and language spoken. All focus groups were audio-taped and transcribed verbatim, with subsequent translation into English for groups conducted in other languages. Data analysis was performed by combining the key elements of grounded theory and content analysis with the assistance of the qualitative software ATLAS/ti 5.0. Five domains (pain, physical disability, other symptoms of OA, mental health, and social health) were identified from the 74 items reported as important by at least one subject. These domains were important for subjects from all ethnic groups with the exception of social health, which was more often important for Malay subjects. Items more commonly reported as important in the pain, physical disability, and other symptoms of OA domains were generally similar across ethnic groups. In contrast, important items in the mental and social health domains differed among ethnic groups. The impact of knee OA on HRQoL is broadly similar in both Asian and Western socio-cultural contexts. Both similarities and differences in important domains and items were identified among subjects with knee OA from three major Asian ethnic groups.

Minority Ethnic Students and Science Participation: a Qualitative Mapping of Achievement, Aspiration, Interest and Capital

NASA Astrophysics Data System (ADS)

Wong, Billy

2016-02-01

In the UK, the `leaky pipeline' metaphor has been used to describe the relationship between ethnicity and science participation. Fewer minority ethnic students continue with science in post-compulsory education, and little is known about the ways in which they participate and identify with science, particularly in the secondary school context. Drawing on an exploratory study of 46 interviews and 22 h of classroom observations with British students (aged 11-14) from Black Caribbean, Bangladeshi, Pakistani, Indian and Chinese ethnic backgrounds, this paper identified five `types' of science participation among minority ethnic students. The five types of science participation emerged from an analysis of students' science achievement, science aspiration, science interest and science capital. The characteristics of the five types are as follows: Science adverse students have no aspirations towards science and lacked interest, achievement and capital in science. Science intrinsic students have high science aspirations, interest and capital but low science attainment. Students who are science intermediate have some aspirations, interest and capital in science, with average science grades. Science extrinsic students achieve highly in science, have some science capital but lacked science aspirations and/or interest. Science prominent students are high science achievers with science aspirations, high levels of interest and capital in science. The findings highlight that minority ethnic students participate in science in diverse ways. Policy implications are suggested for each type as this paper provides empirical evidence to counter against public (and even some academic) discourses of minority ethnic students as a homogeneous group.

Human resources for health: task shifting to promote basic health service delivery among internally displaced people in ethnic health program service areas in eastern Burma/Myanmar.

PubMed

Low, Sharon; Tun, Kyaw Thura; Mhote, Naw Pue Pue; Htoo, Saw Nay; Maung, Cynthia; Kyaw, Saw Win; Shwe Oo, Saw Eh Kalu; Pocock, Nicola Suyin

2014-01-01

Burma/Myanmar was controlled by a military regime for over 50 years. Many basic social and protection services have been neglected, specifically in the ethnic areas. Development in these areas was led by the ethnic non-state actors to ensure care and the availability of health services for the communities living in the border ethnic-controlled areas. Political changes in Burma/Myanmar have been ongoing since the end of 2010. Given the ethnic diversity of Burma/Myanmar, many challenges in ensuring health service coverage among all ethnic groups lie ahead. A case study method was used to document how existing human resources for health (HRH) reach the vulnerable population in the ethnic health organizations' (EHOs) and community-based organizations' (CBHOs) service areas, and their related information on training and services delivered. Mixed methods were used. Survey data on HRH, service provision, and training were collected from clinic-in-charges in 110 clinics in 14 Karen/Kayin townships through a rapid-mapping exercise. We also reviewed 7 organizational and policy documents and conducted 10 interviews and discussions with clinic-in-charges. Despite the lack of skilled medical professionals, the EHOs and CBHOs have been serving the population along the border through task shifting to less specialized health workers. Clinics and mobile teams work in partnership, focusing on primary care with some aspects of secondary care. The rapid-mapping exercise showed that the aggregate HRH density in Karen/Kayin state is 2.8 per 1,000 population. Every mobile team has 1.8 health workers per 1,000 population, whereas each clinic has between 2.5 and 3.9 health workers per 1,000 population. By reorganizing and training the workforce with a rigorous and up-to-date curriculum, EHOs and CBHOs present a viable solution for improving health service coverage to the underserved population. Despite the chronic conflict in Burma/Myanmar, this report provides evidence of the substantive system of health care provision and access in the Karen/Kayin State over the past 20 years. It underscores the climate of vulnerability of the EHOs and CBHOs due to lack of regional and international understanding of the political complexities in Burma/Myanmar. As Association of Southeast Asian Nations (ASEAN) integration gathers pace, this case study highlights potential issues relating to migration and health access. The case also documents the challenge of integrating indigenous and/or cross-border health systems, with the ongoing risk of deepening ethnic conflicts in Burma/Myanmar as the peace process is negotiated.

Human resources for health: task shifting to promote basic health service delivery among internally displaced people in ethnic health program service areas in eastern Burma/Myanmar

PubMed Central

Low, Sharon; Tun, Kyaw Thura; Mhote, Naw Pue Pue; Htoo, Saw Nay; Maung, Cynthia; Kyaw, Saw Win; Shwe Oo, Saw Eh Kalu; Pocock, Nicola Suyin

2014-01-01

Background Burma/Myanmar was controlled by a military regime for over 50 years. Many basic social and protection services have been neglected, specifically in the ethnic areas. Development in these areas was led by the ethnic non-state actors to ensure care and the availability of health services for the communities living in the border ethnic-controlled areas. Political changes in Burma/Myanmar have been ongoing since the end of 2010. Given the ethnic diversity of Burma/Myanmar, many challenges in ensuring health service coverage among all ethnic groups lie ahead. Methods A case study method was used to document how existing human resources for health (HRH) reach the vulnerable population in the ethnic health organizations’ (EHOs) and community-based organizations’ (CBHOs) service areas, and their related information on training and services delivered. Mixed methods were used. Survey data on HRH, service provision, and training were collected from clinic-in-charges in 110 clinics in 14 Karen/Kayin townships through a rapid-mapping exercise. We also reviewed 7 organizational and policy documents and conducted 10 interviews and discussions with clinic-in-charges. Findings Despite the lack of skilled medical professionals, the EHOs and CBHOs have been serving the population along the border through task shifting to less specialized health workers. Clinics and mobile teams work in partnership, focusing on primary care with some aspects of secondary care. The rapid-mapping exercise showed that the aggregate HRH density in Karen/Kayin state is 2.8 per 1,000 population. Every mobile team has 1.8 health workers per 1,000 population, whereas each clinic has between 2.5 and 3.9 health workers per 1,000 population. By reorganizing and training the workforce with a rigorous and up-to-date curriculum, EHOs and CBHOs present a viable solution for improving health service coverage to the underserved population. Conclusion Despite the chronic conflict in Burma/Myanmar, this report provides evidence of the substantive system of health care provision and access in the Karen/Kayin State over the past 20 years. It underscores the climate of vulnerability of the EHOs and CBHOs due to lack of regional and international understanding of the political complexities in Burma/Myanmar. As Association of Southeast Asian Nations (ASEAN) integration gathers pace, this case study highlights potential issues relating to migration and health access. The case also documents the challenge of integrating indigenous and/or cross-border health systems, with the ongoing risk of deepening ethnic conflicts in Burma/Myanmar as the peace process is negotiated. PMID:25280737

Metric and morphological assessment of facial features: a study on three European populations.

PubMed

Ritz-Timme, S; Gabriel, P; Tutkuviene, J; Poppa, P; Obertová, Z; Gibelli, D; De Angelis, D; Ratnayake, M; Rizgeliene, R; Barkus, A; Cattaneo, C

2011-04-15

Identification from video surveillance systems is becoming more and more frequent in the forensic practice. In this field, different techniques have been improved such as height estimation and gait analysis. However, the most natural approach for identifying a person in everyday life is based on facial characteristics. Scientifically, faces can be described using morphological and metric assessment of facial features. The morphological approach is largely affected by the subjective opinion of the observer, which can be mitigated by the application of descriptive atlases. In addition, this approach requires one to investigate which are the most common and rare facial characteristics in different populations. For the metric approach further studies are necessary in order to point out possible metric differences within and between different populations. The acquisition of statistically adequate population data may provide useful information for the reconstruction of biological profiles of unidentified individuals, particularly concerning ethnic affiliation, and possibly also for personal identification. This study presents the results of the morphological and metric assessment of the head and face of 900 male subjects between 20 and 31 years from Italy, Germany and Lithuania. The evaluation of the morphological traits was performed using the DMV atlas with 43 pre-defined facial characteristics. The frequencies of the types of facial features were calculated for each population in order to establish the rarest characteristics which may be used for the purpose of a biological profile and consequently for personal identification. Metric analysis performed in vivo included 24 absolute measurements and 24 indices of the head and face, including body height and body weight. The comparison of the frequencies of morphological facial features showed many similarities between the samples from Germany, Italy and Lithuania. However, several characteristics were rare or significantly more or less common in one population compared to the other two. On the other hand, all measurements and indices, except for labial width and intercanthal-mouth index showed significant differences between the three populations. As far as comparisons with other samples are concerned, the three European Caucasian samples differed from North American Caucasian, African and Asian groups as concerns the frequency of the morphological traits and the mean values of the metric analysis. The metric and morphological data collected from three European populations may be useful for forensic purposes in the construction of biological profiles and in screening for personal identification. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Ecosystem Services Assessment of the Nemunas River Delta

EPA Science Inventory

The concept of ecosystem services recognizes the services, and benefits, provided to people by ecosystems. The Nemunas River Delta, in Lithuania, provides many ecosystem services to the people of the area, including food, fuel, transportation, climate regulation, water purificati...

DefenseLink Special: Travels with Rumsfeld, October 2005

Science.gov Websites

DefenseLink.mil Aug. 04, 2015 War on Terror Transformation News Products Press Resources Images Websites Contact Lithuania, praised Mongolia for its support in the war on terror. Story Photo: See caption below. A 'PROUD

Alfalfa witches'-broom

USDA-ARS?s Scientific Manuscript database

Alfalfa witches'-broom was first reported in 1969 in Australia and later in South Africa, Canada, and Saudi Arabia. More recently, specific phytoplasmas associated with alfalfa witches'-broom have been identified from symptomatic plants in the United States (Wisconsin), Italy, Lithuania, Oman, Ira...

CERN welcomes new members

NASA Astrophysics Data System (ADS)

2017-08-01

Lithuania is on course to become an associate member of CERN, pending final approval by the Lithuanian parliament. Associate membership will allow representatives of the Baltic nation to take part in meetings of the CERN Council, which oversees the Geneva-based physics lab.

MLST genotypes of Campylobacter jejuni isolated from broiler products, dairy cattle and human campylobacteriosis cases in Lithuania.

PubMed

Ramonaite, Sigita; Tamuleviciene, Egle; Alter, Thomas; Kasnauskyte, Neringa; Malakauskas, Mindaugas

2017-06-15

Campylobacter (C.) jejuni is the leading cause of human campylobacteriosis worldwide. We performed a molecular epidemiological study to investigate the genetic relationship among C. jejuni strains isolated from human diarrhoeal patients, broiler products and dairy cattle in Lithuania. The C. jejuni isolates from human clinical cases, dairy cattle and broiler products were genotyped using multilocus sequence typing (MLST). Allele numbers for each housekeeping gene, sequence type (ST), and clonal complex (CC) were assigned by submitting the DNA sequences to the C. jejuni MLST database ( http://pubmlst.org/campylobacter ). Based on the obtained sequence data of the housekeeping genes a phylogenetic analysis of the strains was performed and a minimum spanning tree (MST) was calculated. Among the 262 C. jejuni strains (consisting of 43 strains isolated from dairy cattle, 102 strains isolated from broiler products and 117 clinical human C. jejuni strains), 82 different MLST sequence types and 22 clonal complexes were identified. Clonal complexes CC21 and CC353 predominated among the C. jejuni strains. On ST-level, five sequence types (ST-5, ST-21, ST-50, ST-464 and ST-6410) were dominating and these five STs accounted for 35.9% (n = 94) of our isolates. In addition, 51 (19.5%) C. jejuni strains representing 27 (32.9%) STs were reported for the first time in the PubMLST database ( http://pubmlst.org/campylobacter ). The highest Czekanowski index or proportional similarity index (PSI) was calculated for C. jejuni strains isolated from human campylobacteriosis cases and broiler products (PSI = 0.32) suggesting a strong link between broiler strains and human cases. The PSI of dairy cattle and human samples was lower (PSI = 0.11), suggesting a weaker link between bovine strains and human cases. The calculated Simpson's index of all C. jejuni isolates showed a high genetic diversity (D = 0.96). Our results suggest that broiler products are the most important source of human campylobacteriosis in Lithuania. The study provides information on MLST type distribution and genetic relatedness of C. jejuni strains from humans, broiler products and dairy cattle in Lithuania for the first time, enabling a better understanding of the transmission pathways of C. jejuni in this country.

The relationship of hostility, negative affect and ethnicity to cardiovascular responses: an ambulatory study in Singapore.

PubMed

Enkelmann, Hwee Chong; Bishop, George D; Tong, Eddie M W; Diong, Siew Maan; Why, Yong Peng; Khader, Majeed; Ang, Jansen

2005-05-01

This study tested the hypotheses that ambulatory heart rate and blood pressure would be higher for individuals high but not low in hostility when they experienced negative affect or social stress and that this interaction would be stronger for Indians compared with other Singapore ethnic groups. Ambulatory blood pressure monitoring was done on 108 male Singapore patrol officers as they went about their daily duties. After each BP measurement participants completed a computerized questionnaire including items on emotional experience. Individuals high in hostility showed higher systolic blood pressure when reporting negative affect whereas this was not true for those low in hostility. Ethnic differences were obtained such that Indians showed an increase in mean arterial pressure when angered whereas MAP was negatively related to anger for Malays and unrelated for Chinese. Also a three-way interaction between ethnicity, hostility, and social stress indicated that hostility and social stress interacted in their effects on DBP for Indian participants but not for Chinese or Malays. Finally, a three-way interaction was obtained between ethnicity, hostility and negative affect for heart rate in which heart rate increased with increasing levels of negative affect for Chinese high in hostility and Malays low in hostility but decreased with increasing negative affect for all other participants. These data are consistent with higher CHD rates among individuals high in hostility and also provide additional evidence on ethnic differences in cardiovascular reactivity in Singapore.

A High-Density Admixture Map for Disease Gene Discovery in African Americans

PubMed Central

Smith, Michael W. ; Patterson, Nick ; Lautenberger, James A. ; Truelove, Ann L. ; McDonald, Gavin J. ; Waliszewska, Alicja ; Kessing, Bailey D. ; Malasky, Michael J. ; Scafe, Charles ; Le, Ernest ; De Jager, Philip L. ; Mignault, Andre A. ; Yi, Zeng ; de Thé, Guy ; Essex, Myron ; Sankalé, Jean-Louis ; Moore, Jason H. ; Poku, Kwabena ; Phair, John P. ; Goedert, James J. ; Vlahov, David ; Williams, Scott M. ; Tishkoff, Sarah A. ; Winkler, Cheryl A. ; De La Vega, Francisco M. ; Woodage, Trevor ; Sninsky, John J. ; Hafler, David A. ; Altshuler, David ; Gilbert, Dennis A. ; O’Brien, Stephen J. ; Reich, David 

2004-01-01

Admixture mapping (also known as “mapping by admixture linkage disequilibrium,” or MALD) provides a way of localizing genes that cause disease, in admixed ethnic groups such as African Americans, with ∼100 times fewer markers than are required for whole-genome haplotype scans. However, it has not been possible to perform powerful scans with admixture mapping because the method requires a dense map of validated markers known to have large frequency differences between Europeans and Africans. To create such a map, we screened through databases containing ∼450,000 single-nucleotide polymorphisms (SNPs) for which frequencies had been estimated in African and European population samples. We experimentally confirmed the frequencies of the most promising SNPs in a multiethnic panel of unrelated samples and identified 3,011 as a MALD map (1.2 cM average spacing). We estimate that this map is ∼70% informative in differentiating African versus European origins of chromosomal segments. This map provides a practical and powerful tool, which is freely available without restriction, for screening for disease genes in African American patient cohorts. The map is especially appropriate for those diseases that differ in incidence between the parental African and European populations. PMID:15088270

Women in Physics in Lithuania: Challenges and Actions

NASA Astrophysics Data System (ADS)

Šatkovskienė, Dalia

2009-04-01

The gender equality problem in physics is discussed on the basis of Lithuanian statistics and results of the project, "Baltic States Network: Women in Sciences and High Technology" (BASNET), initiated by Lithuanian women physicists and financed by the European Commission.

GIS walking maps to promote physical activity in low-income public housing communities: a qualitative examination.

PubMed

McNeill, Lorna H; Emmons, Karen

2012-01-01

Walking is the most commonly reported leisure-time activity. Members of racial/ethnic minority groups and people of low socioeconomic status disproportionately live in urban environments that are perceived to be unsafe, thereby reducing opportunities for engaging in walking. We examined the use of walking maps for increasing physical activity (PA) among low-income residents of public housing sites in Boston, Massachusetts. PA facilities, local businesses, and destinations in a walkable half-mile radius of the housing community were identified and plotted on maps by using geographic information systems technology. Four focus groups (n = 24) were conducted to learn how the walking maps were used by the residents and to understand map features that promoted use. Maps were used by participants to increase their PA, and use of the maps increased participants' awareness of community resources. Maps changed participants' perception of distances and were discussed as a means of fostering a sense of community. Use of the maps also increased participants' awareness of neighborhood incivilities. Barriers to map use were difficulty in interpreting the maps and lack of access to the maps. Walking maps that display PA opportunities and resources may be useful in increasing walking among residents of public housing sites.

From Afar to Zulu: A Dictionary of African Cultures.

ERIC Educational Resources Information Center

Haskins, Jim; Biondi, Joann

This resource provides information on over 30 of Africa's most populous and well-known ethnic groups. The text concisely describes the history, traditions, environment, social structure, religion, and daily lifestyles of these diverse cultures. Each entry opens with a map outlining the area populated by the group and a list of key data regarding…

The Shaping of Modern Hawaiian History: Databook and Atlas; Teacher Answer Book.

ERIC Educational Resources Information Center

Tamura, Eileen; And Others

This book is intended for use as a supplement to a five-unit instructional series, "The Shaping of Modern Hawaiian History." It presents information on land use, population and ethnic diversity, government, politics, the economy, and Hawaii's place in the Pacific. Provided are many graphs, tables, readings, documents, and maps, which…

Mapping Language Ideologies in Multi-Ethnic Urban Europe: The Case of Parisian French

ERIC Educational Resources Information Center

Stewart, Christopher Michael

2012-01-01

Although the modern multicultural European metropolis has brought previously disparate groups into close contact, little research has focused on the effect of these shifting demographic patterns on language attitudes and ideologies. This is probably due to the sensitive nature of issues relating to immigration which may evoke contexts of…

From Redlining to Benevolent Societies: The Emancipatory Power of Spatial Thinking

ERIC Educational Resources Information Center

Mitchell, Katharyne; Elwood, Sarah

2012-01-01

This study highlights the power of place, and reconceptualizes geography education as integral to the larger project of teaching for democratic citizenship. Using an interactive web platform, the researchers asked 29 seventh grade girls to research and map significant cultural and historical places associated with an ethnic group, or women, in the…

Mapping the Linguistic Landscape of Athens: The Case of Shop Signs

ERIC Educational Resources Information Center

Nikolaou, Alexander

2017-01-01

This paper focuses on the linguistic composition of commercial signs in the linguistic landscape (LL) of Athens, Greece. Previous studies have mainly been carried out in officially multilingual and multi-ethnic areas [Ben-Rafael, E., Shohamy, E., Amara, M. H., & Trumper-Hecht, N. (2006). "Linguistic landscape as symbolic construction of…

Asia & Oceania Today: A Reproducible Atlas. 1995 Revised Edition. World Eagle's Today Series.

ERIC Educational Resources Information Center

Independent Broadcasting Associates, Inc., Littleton, MA.

This book contains blank outline maps of the continent or region, tables, and graphics depicting various aspects of Asia and Oceania. Sections of the book include: (1) "The Land and Population Figures"; (2) "Cities and Countries"; (3) "People: Languages, Literacy, Ethnic groups, Demographic Statistics and Projections,…

Discovery and fine-mapping of loci associated with monounsaturated fatty acids through trans-ethnic meta-analysis in Chinese and European populations

USDA-ARS?s Scientific Manuscript database

Monounsaturated fatty acids (MUFAs) are unsaturated fatty acids with one double bond and are derived from endogenous synthesis and dietary intake. Accumulating evidence has suggested that plasma and erythrocyte MUFA levels were associated with cardiometabolic disorders including cardiovascular disea...

Using State and Local Studies to Teach Geographic Concepts.

ERIC Educational Resources Information Center

Fuller, Michael J.; And Others

1982-01-01

Lessons involve K-12 students in analyzing teacher-developed state and local thematic maps, identifying countries of the world with which their city has a linkage as indicated by local ethnic restaurants, discussing local companies involved in international trade, and learning about foreign-made products in their home and community. (RM)

Exploring links between juvenile offenders and social disorganization at a large map scale: a Bayesian spatial modeling approach

NASA Astrophysics Data System (ADS)

Law, Jane; Quick, Matthew

2013-01-01

This paper adopts a Bayesian spatial modeling approach to investigate the distribution of young offender residences in York Region, Southern Ontario, Canada, at the census dissemination area level. Few geographic researches have analyzed offender (as opposed to offense) data at a large map scale (i.e., using a relatively small areal unit of analysis) to minimize aggregation effects. Providing context is the social disorganization theory, which hypothesizes that areas with economic deprivation, high population turnover, and high ethnic heterogeneity exhibit social disorganization and are expected to facilitate higher instances of young offenders. Non-spatial and spatial Poisson models indicate that spatial methods are superior to non-spatial models with respect to model fit and that index of ethnic heterogeneity, residential mobility (1 year moving rate), and percentage of residents receiving government transfer payments are, respectively, the most significant explanatory variables related to young offender location. These findings provide overwhelming support for social disorganization theory as it applies to offender location in York Region, Ontario. Targeting areas where prevalence of young offenders could or could not be explained by social disorganization through decomposing the estimated risk map are helpful for dealing with juvenile offenders in the region. Results prompt discussion into geographically targeted police services and young offender placement pertaining to risk of recidivism. We discuss possible reasons for differences and similarities between the previous findings (that analyzed offense data and/or were conducted at a smaller map scale) and our findings, limitations of our study, and practical outcomes of this research from a law enforcement perspective.

Land use impacts on lake water quality in Alytus region (Lithuania)

NASA Astrophysics Data System (ADS)

Pereira, Paulo; Laukonis, Rymvidas

2016-04-01

Land use has important impacts on soils, surface and ground water quality. Urban agricultural areas are an important source of pollutants, which can reach lakes through surface runoff and underground circulation. Human intervention in the landscape is one of the major causes pollution and land degradation, thus it is very important to understand the impacts of and use on environment and if they have some spatial pattern (Pereira et al., 2013, 2015; Brevik et al., 2016). The identification of the spatial pattern of lakes pollution is in Alytus area (Lithuania) is fundamental, since they provide an important range of ecosystem services to local communities, including food and recreational activities. Thus, the degradation of these environments can induce important economic losses. In this context, it is import to identify the areas with high pollutant accumulation and the environmental and human factors responsible for it. The objective of this work is to study identify the amount of some important nutrients resultant from human activities in lake water quality in Alytus region (Lithuania). Alytus region is located in southern part of Lithuania and has an approximate area of 40 km2. Inside this region we analyzed several water quality parameters of 55 lakes, including, pH, electrical conductivity (EC), suspended materials (SM), water clarity (WC) biochemical oxygen demand (BDO), total phosphorous (TP), total Nitrogen (TN), dissolved organic carbon (DOC), as other environmental variables as altitude, lake maximum deep (MD), lake area and land use according Corine land cover classification (CLC2006). Previous to data analysis, data normality and homogeneity of the variances, was assessed with the Shapiro-wilk and Leven's test, respectively. The majority of the data did not respect the Gaussian distribution and the heteroscedasticity, even after a logarithmic, and box-cox transformation. Thus, in this work we used the logarithmic transformed data to do a principal component analysis (PCA), based on the correlation matrix. The loadings of factors that at least explained one of the variables were used for a hot spot analysis, in order to identify if there was a spatial pattern in the variables distribution (Pereira et al., 2010, 2016). The results showed that in Alytus region 45.5% of the land use was classified as agricultural area, 47.3% as forest and semi-natural areas, 3.3% as water bodies, 2% as artificial surfaces and 1.9% as wetlands. The water properties of the studied lakes were the follow: pH 8.3±0.41, EC 336.31±106.49 μS/cm, 9.55±3.09 mg/l, WC 2.55±1.41 meters, BDO 3.53±1.30 mg/l, TP 0.0425±0.027 mg/l, TN 0.92±0.39 mg/l, DOC 9.61±0.79 mg/l. On average, the altitude of the lakes was 113.98±17.06 meters, MD 15.98±12.08 and lake area 243.85±386.52 ha. The PCA identified three different groups (factors). The factor 1 had high loadings in MD and WC, and high negative loadings in BDS, TP, TN and SM. The factor 2 showed high negative loadings in pH, EC and DOC. Finally, the factor 3 had high positive loadings in the area of the lake and high negative loadings in altitude. The hot spot analysis carried out with the loadings of factor 1 showed that that the area at northeast of Alytus region had a significant concentration lakes with high amounts of BDS, TP, TN, and SM, and in the west an area of lakes with high WC and MD. The hot spot analysis applied to the factor 2 loadings, showed that there was a group of lakes with high pH, EC and DOC, and a cluster located in the northeast part of Alytus region with a low level of pH, EC and DOC. Finally, the hot spot analysis applied to the factor 3 loadings, identified that the areas where the high lake area were located in the northwest of the study area, and small lakes were identified in the northeast. The lakes located at high altitude were located in the northeast area and the ones at low altitude at northeast part of Alytus area. Overall, the area with lakes with high pollution are located at northwest of the study area, where the lakes were more shallow, the altitude was low and the majority of the surroundings are covered by agricultural areas. The degradation of water quality of this area may be attributed to the fertilizers and pesticides applied by farmers in this area, contributing to the degradation of water quality and the quality of the services offered by this area. References Brevik, E., Baumgarten, A., Calzolari, C., Jordan, A., Kabala, C., Miller, B., Pereira, P. Editorial Historical perspectives and future needs in soil mapping, classification and pedological modelling, Geoderma, 264, Part B, 253-255. Pereira, P., Úbeda, X., Baltrenaite, E. (2010) Mapping Total Nitrogen in ash after a Wildfire, a microplot analysis, Ekologija, 56 (3-4), 144-152. Pereira, P., Cerdà, A., Jordán, A., Bolutiene, V., Úbeda, X., Pranskevicius, M., Mataix-Solera, J. (2013) Spatio-temporal vegetation recuperation after a grassland fire in Lithuania, Procedia Environmental Sciences, 19:856-864 Pereira, P., Gimenez-Morera, A., Novara, A., Keesstra, S., Jordan, A., Masto, R.E., Cerda, A. (2015) Soil erosion on road and railways embankments in the Canyoles river watershed, Eastern Spain, Hydrology and Earth System Sciences, Discussions, 12, 12947-12985.doi:10.5194/hessd-12-12947-2015 Pereira, P., Oliva, M., Misiune, I. (2016) Spatial interpolation of precipitation indexes in Sierra Nevada (Spain): comparing the performance of some interpolation methods, Theoretical and Applied Climatology (in press), doi:10.1007/s00704-015-1606-8

Racial and ethnic disparities in stroke outcomes: a scoping review of post-stroke disability assessment tools.

PubMed

Burns, Suzanne Perea; White, Brandi M; Magwood, Gayenell; Ellis, Charles; Logan, Ayaba; Jones Buie, Joy N; Adams, Robert J

2018-03-23

To identify how post-stroke disability outcomes are assessed in studies that examine racial/ethnic disparities and to map the identified assessment content to the International Classification of Functioning, Disability, and Health (ICF) across the time course of stroke recovery. We conducted a scoping review of the literature. Articles published between January 2001 and July 2017 were identified through Scopus, PubMed, CINAHL, and PsycINFO according to predefined inclusion and exclusion criteria. We identified 1791 articles through database and hand-searching strategies. Of the articles, 194 met inclusion criteria for full-text review, and 41 met inclusion criteria for study inclusion. The included studies used a variety of outcome measures encompassing domains within the ICF: body functions, activities, participation, and contextual factors across the time course of stroke recovery. We discovered disproportionate representation among racial/ethnic groups in the post-stroke disability disparities literature. A wide variety of assessments are used to examine disparities in post-stroke disability across the time course of stroke recovery. Several studies have identified disparities through a variety of assessments; however, substantial problems abound from the assessments used including inconsistent use of assessments, lacking evidence on the validity of assessments among racial/ethnic groups, and inadequate representation among all racial/ethnic populations comprising the US. Implications for Rehabilitation An enhanced understanding of racial/ethnic disparities in post-stroke disability outcomes is inherently important among rehabilitation practitioners who frequently engage with racial/ethnic minority populations across the time course of stroke recovery. Clinicians should carefully consider the psychometric properties of assessment tools to counter potential racial bias. Clinicians should be aware that many assessments used in stroke rehabilitation lack cultural sensitivity and could result in inaccurate assessment findings.

F-22 Raptors fly into Lithuania as part of European tour > U.S. Air Force >

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The Book Speeches Archive Former AF Top 3 Viewpoints and Speeches Air Force Warrior Games 2017 Events 2018 Air Force Strategic Documents Desert Storm 25th Anniversary Observances DoD Warrior Games

9 CFR 94.11 - Restrictions on importation of meat and other animal products from specified regions.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., Hungary, Ireland, Italy, Latvia, Liechtenstein, Lithuania, Luxembourg, Namibia (excluding the region north... by adding the words, “Republic of Korea,” after the word “Japan,”, effective Jan. 12, 2010. At 75 FR...

Socioeconomic gradients in sexually transmitted diseases: a geographic information system-based analysis of poverty, race/ethnicity, and gonorrhea rates in California, 2004-2006.

PubMed

Springer, Yuri P; Samuel, Michael C; Bolan, Gail

2010-06-01

We quantified the relationship between gonorrheal infection rates in California and a measure of poverty status and investigated how this relationship and the spatial dispersion of cases varied among the 4 dominant racial/ethnic groups in the state. We geocoded gonorrhea cases reported in California between 2004 and 2006, and estimated the poverty status of each case by using the percentage of residents living below poverty in the census tract of residence. We calculated infection rates for African American, Asian, Hispanic, and White cases in each of 4 poverty strata. We mapped cases to visualize the patterns of spatial dispersion associated with each race/ethnicity-poverty combination. There was a strong positive relationship between poverty and infection, but racial/ethnic disparities in infection, driven by a disproportionate level of gonorrhea among African Americans, eclipsed this differential. The degree of spatial aggregation varied substantially among groups and was especially pronounced for African Americans with gonorrhea in the highest poverty category. Prevention efforts should target low-income neighborhood "hot spots" to reach the largest numbers of cases, particularly among African Americans.

Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility

PubMed Central

Cook, James P; Morris, Andrew P

2016-01-01

Genome-wide association studies (GWAS) have traditionally been undertaken in homogeneous populations from the same ancestry group. However, with the increasing availability of GWAS in large-scale multi-ethnic cohorts, we have evaluated a framework for detecting association of genetic variants with complex traits, allowing for population structure, and developed a powerful test of heterogeneity in allelic effects between ancestry groups. We have applied the methodology to identify and characterise loci associated with susceptibility to type 2 diabetes (T2D) using GWAS data from the Resource for Genetic Epidemiology on Adult Health and Aging, a large multi-ethnic population-based cohort, created for investigating the genetic and environmental basis of age-related diseases. We identified a novel locus for T2D susceptibility at genome-wide significance (P<5 × 10−8) that maps to TOMM40-APOE, a region previously implicated in lipid metabolism and Alzheimer's disease. We have also confirmed previous reports that single-nucleotide polymorphisms at the TCF7L2 locus demonstrate the greatest extent of heterogeneity in allelic effects between ethnic groups, with the lowest risk observed in populations of East Asian ancestry. PMID:27189021

Longer breastfeeding is an independent protective factor against development of type 1 diabetes mellitus in childhood.

PubMed

Sadauskaite-Kuehne, Vaiva; Ludvigsson, Johnny; Padaiga, Zilvinas; Jasinskiene, Edita; Samuelsson, Ulf

2004-01-01

Early weaning diet, early introduction of breast milk substitution and cow's milk have been shown to increase the risk of type 1 diabetes later in life. It is also shown that older maternal age, maternal education, preeclampsia, prematurity, neonatal illness and neonatal icterus caused by blood group incompatibility, infections and stress might be risk factors for type 1 diabetes. We aimed to determine whether early nutrition is an independent risk factor for diabetes despite other life events. Data from 517 children (268 boys and 249 girls) in south-east of Sweden and 286 children (133 boys and 153 girls) in Lithuania in the age group of 0 to 15 years with newly diagnosed type 1 diabetes mellitus were included into analysis. Three age- and sex-matched healthy controls were randomly selected. Response rate in control families in Sweden was 72.9% and in Lithuania 94.8%. Information was collected via questionnaires. Exclusive breastfeeding longer than five months (odds ratio 0.54, 95% confidence interval 0.36-0.81) and total breastfeeding longer than 7 (0.56, 0.38-0.84) or 9 months (0.61, 0.38-0.84), breastfeeding substitution that started later than the third month (0.57, 0.33-0.98) among Swedish children 5 to 9 years old and later than the seventh month (0.24, 0.07-0.84) among all Swedish children is protective against diabetes when adjusted for all other above-listed risk factors. In Lithuania, exclusive breastfeeding longer than two months in the age group of 5 to 9 years is protective (0.58, 0.34-0.99) when adjusted for other factors. Longer exclusive and total breastfeeding appears as an independent protective factor against type 1 diabetes. Copyright 2004 John Wiley & Sons, Ltd.

Linked versus unlinked estimates of mortality and length of life by education and marital status: evidence from the first record linkage study in Lithuania.

PubMed

Shkolnikov, Vladimir M; Jasilionis, Domantas; Andreev, Evgeny M; Jdanov, Dmitri A; Stankuniene, Vladislava; Ambrozaitiene, Dalia

2007-04-01

Earlier studies have found large and increasing with time differences in mortality by education and marital status in post-Soviet countries. Their results are based on independent tabulations of population and deaths counts (unlinked data). The present study provides the first census-linked estimates of group-specific mortality and the first comparison between census-linked and unlinked mortality estimates for a post-Soviet country. The study is based on a data set linking 140,000 deaths occurring in 2001-2004 in Lithuania with the population census of 2001. The same socio-demographic information about the deceased is available from both the census and death records. Cross-tabulations and Poisson regressions are used to compare linked and unlinked data. Linked and unlinked estimates of life expectancies and mortality rate ratios are calculated with standard life table techniques and Poisson regressions. For the two socio-demographic variables under study, the values from the death records partly differ from those from the census records. The deviations are especially significant for education, with 72-73%, 66-67%, and 82-84% matching for higher education, secondary education, and lower education, respectively. For marital status, deviations are less frequent. For education and marital status, unlinked estimates tend to overstate mortality in disadvantaged groups and they understate mortality in advantaged groups. The differences in inter-group life expectancy and the mortality rate ratios thus are significantly overestimated in the unlinked data. Socio-demographic differences in mortality previously observed in Lithuania and possibly other post-Soviet countries are overestimated. The growth in inequalities over the 1990s is real but might be overstated. The results of this study confirm the existence of large and widening health inequalities but call for better data.

Phylogenetic characterization of Canine Parvovirus VP2 partial sequences from symptomatic dogs samples.

PubMed

Zienius, D; Lelešius, R; Kavaliauskis, H; Stankevičius, A; Šalomskas, A

2016-01-01

The aim of the present study was to detect canine parvovirus (CPV) from faecal samples of clinically ill domestic dogs by polymerase chain reaction (PCR) followed by VP2 gene partial sequencing and molecular characterization of circulating strains in Lithuania. Eleven clinically and antigen-tested positive dog faecal samples, collected during the period of 2014-2015, were investigated by using PCR. The phylogenetic investigations indicated that the Lithuanian CPV VP2 partial sequences (3025-3706 cds) were closely related and showed 99.0-99.9% identity. All Lithuanian sequences were associated with one phylogroup, but grouped in different clusters. Ten of investigated Lithuanian CPV VP2 sequences were closely associated with CPV 2a antigenic variant (99.4% nt identity). Five CPV VP2 sequences from Lithuania were related to CPV-2a, but were rather divergent (6.8 nt differences). Only one CPV VP2 sequence from Lithuania was associated (99.3% nt identity) with CPV-2b VP2 sequences from France, Italy, USA and Korea. The four of eleven investigated Lithuanian dogs with CPV infection symptoms were vaccinated with CPV-2 vaccine, but their VP2 sequences were phylogenetically distantly associated with CPV vaccine strains VP2 sequences (11.5-15.8 nt differences). Ten Lithuanian CPV VP2 sequences had monophyletic relations among the close geographically associated samples, but five of them were rather divergent (1.0% less sequence similarity). The one Lithuanian CPV VP2 sequence was closely related with CPV-2b antigenic variant. All the Lithuanian CPV VP2 partial sequences were conservative and phylogenetically low associated with most commonly used CPV vaccine strains.

Menopause and myocardial infarction risk among employed women in relation to work and family psychosocial factors in Lithuania.

PubMed

Malinauskiene, Vilija; Tamosiunas, Abdonas

2010-05-01

To assess the relationship between menopause and age at menopause and the risk of the first non-fatal myocardial infarction taking into account the possible influence of psychosocial job characteristics, marital stress, level of social support, educational level, occupation, age and traditional ischemic heart disease risk factors. Population-based case-control study among 35-61 years old employed women in Kaunas, Lithuania. Totally 122 myocardial infarction cases and 371 controls were interviewed in 2001-2004. The logistic regression analysis was performed. Younger age at menopause (

Increasing thyroid cancer incidence in Lithuania in 1978-2003.

PubMed

Smailyte, Giedre; Miseikyte-Kaubriene, Edita; Kurtinaitis, Juozas

2006-12-11

The aim of this paper is to analyze changes in thyroid cancer incidence trends in Lithuania during the period 1978-2003 using joinpoint regression models, with special attention to the period 1993-2003. The study was based on all cases of thyroid cancer reported to the Lithuanian Cancer Registry between 1978 and 2003. Age group-specific rates and standardized rates were calculated for each gender, using the direct method (world standard population). The joinpoint regression model was used to provide estimated annual percentage change and to detect points in time where significant changes in the trends occur. During the study period the age-standardized incidence rates increased in males from 0.7 to 2.5 cases per 100,000 and in females from 1.5 to 11.4 per 100,000. Annual percentage changes during this period in the age-standardized rates were 4.6% and 7.1% for males and females, respectively. Joinpoint analysis showed two time periods with joinpoint in the year 2000. A change in the trend occurred in which a significant increase changed to a dramatic increase in thyroid cancer incidence rates. Papillary carcinoma and stage I thyroid cancer increases over this period were mainly responsible for the pattern of changes in trend in recent years. A moderate increase in thyroid cancer incidence has been observed in Lithuania between the years 1978 and 2000. An accelerated increase in thyroid cancer incidence rates took place in the period 2000-2003. It seems that the increase in thyroid cancer incidence can be attributed mainly to the changes in the management of non palpable thyroid nodules with growing applications of ultrasound-guided fine needle aspiration biopsy in clinical practice.

Bullying behavior and mental health in healthcare and educational sectors in Kaunas, Lithuania.

PubMed

Bernotaite, Lina; Malinauskiene, Vilija; Leisyte, Palmira

2017-05-16

Investigations on workplace bullying in the countries of Eastern Europe are yet not too extensive. The aim of the study has been to identify the most frequent bullying behavior and to explore the associations with psychological distress and post-traumatic stress symptoms in 3 female-dominated occupations in Kaunas, Lithuania. This crosssectional study employed 517 teachers (response rate (RR) = 71.3%), 174 family physicians (RR = 65.7%) and 311 internal medicine department nurses (RR = 69.1%). The twenty-two-item Negative Acts Questionnaire was used for measuring the exposure to bullying behavior, Goldberg 12-item General Health Questionnaire (GHQ-12) - psychological distress, Event Scale-Revised (IES-R) inventory - post-traumatic stress symptoms, Karasek & Theorell Demand-Control questionnaire - psychosocial job characteristics. The International Business Machines Corporation (IBM) SPSS Statistics version 20.0 was used for performing the statistical analysis. Logistic regression was used for assessing the associations among 22 negative acts as continuous variable and mental health outcomes adjusting to age, psychosocial factors at work and everyday life. Exposure to workplace bullying behavior on a weekly/daily basis was prevalent among family physicians at the rate of 19%, among nurses - 12.9%, among teachers - 4.1%. Even after adjustment to age, psychosocial job characteristics and threatening life events, the exposure to 22 negative acts as continuous variable was significantly associated with psychological distress and post-traumatic stress symptoms for all 3 occupations. Health care sector is particularly affected by workplace bullying. Exposure to bullying behavior was associated with mental health problems for all 3 occupations. Preventive measures are necessary to improve psychosocial work environment conditions in healthcare and educational institutions in Lithuania. Med Pr 2017;68(3):307-314. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.

Low job control and myocardial infarction risk in the occupational categories of Kaunas men, Lithuania

PubMed Central

Malinauskiene, V; Theorell, T; Grazuleviciene, R; Malinauskas, R; Azaraviciene, A

2004-01-01

Study objective: To determine the association between adverse psychosocial characteristics at work and risk of first myocardial infarction in the occupational categories of Kaunas men, Lithuania. Design: The analysis was based upon a case-control study among full time working men in the general population of Kaunas. Outcome measure: First non-fatal myocardial infarction diagnosed in 2001–2002. The Swedish version of the demand-control questionnaire was used to examine the effect of job control and demands. Setting: Kaunas, the second largest city in Lithuania, a former socialist country in a transition market economy. Participants: Cases were 203 men 25–64 years of age with a first non-fatal myocardial infarction and controls were 287 men group randomly selected from the study base. Main results: Low job control had a significant effect on myocardial infarction risk in the general 25–64 year old Kaunas male population (OR = 2.68; 95% CI 1.68 to 4.28) after adjustment for age and socioeconomic status. Low job control was a risk factor in the occupational categories of the increased myocardial infarction risk (1st occupational category—legislators, senior officials and managers and the 8th—plant and machine operators and assemblers; OR = 2.78; 95% CI 1.31 to 5.93 and 2.72; 95% CI 1.56 to 4.89, respectively, after adjustment for age and socioeconomic status). Though the adjusted odds ratio estimates were significantly high for the rest of the occupational categories (2nd—professionals, 3rd—technicians and associate professionals, and 7th—craft and related trades workers). Conclusions: The association between low job control and first myocardial infarction risk was significant for all occupational categories of Kaunas men. PMID:14729894

Roosters to Robots.

ERIC Educational Resources Information Center

McCorkle, Sarapage, Ed.; Suiter, Mary, Ed.

This publication contains six lessons for elementary, secondary, and high school classrooms developed by writers from Belarus, Bulgaria, Latvia, Lithuania, Poland, Ukraine, and the United States. The authors of these lessons were participants in the Training of Writers program developed and conducted by the National Council on Economic Education,…

Clinical cosmobiology: The Lithuanian study 1990 1992

NASA Astrophysics Data System (ADS)

Stoupel, Eliyahu; Petrauskiene, Jadviga; Kalediene, Ramune; Abramson, Evgeny; Sulkes, Jacqueline

1995-12-01

The numbers of deaths from ischaemic heart disease (IHD), stroke (CVA), all accidents except vehicular, vehicular accidents and suicide (overall total, totals for men and women) per month for 36 months (1990 1992) in Lithuania were analysed in relation to: (1) month of the year (1 12); (2) geomagnetic activity; and (3) solar activity. A total of 122227 deaths (64490 men and 57737 women) was studied, and the results compared with those obtained in an earlier study in Israel, differing geographically and climatically from Lithuania. It was shown that the time of year, solar activity, and geomagnetic activity were related to the monthly death distribution, especially regarding death from IHD and suicide. Age and gender differences were apparent in the relationship between death distribution and physical environmental factors. At age >70 years, many of these relationships change. The monthly distribution of deaths from IHD and suicide are adversely correlated with solar activity and with each other. Differences are presumed in serotoninergic effects as caused by environmental influences.

PTSD and Complex PTSD: ICD-11 updates on concept and measurement in the UK, USA, Germany and Lithuania

PubMed Central

Karatzias, Thanos; Cloitre, Marylene; Maercker, Andreas; Kazlauskas, Evaldas; Shevlin, Mark; Hyland, Philip; Bisson, Jonathan I.; Roberts, Neil P.; Brewin, Chris R.

2017-01-01

ABSTRACT The 11th revision to the World Health Organization’s International Classification of Diseases (ICD-11) proposes two distinct sibling conditions: Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD). In this paper, we aim to provide an update on the latest research regarding the conceptual structure and measurement of PTSD and CPTSD using the International Trauma Questionnaire (ITQ) as per ICD-11 proposals in the USA, UK, Germany and Lithuania. Preliminary findings suggest that CPTSD is common in clinical and population samples, although there may be variations across countries in prevalence rates. In clinical samples, preliminary evidence suggests that CPTSD is a more commonly observed condition than PTSD. Preliminary evidence also suggests that the ITQ scores are reliable and valid and can adequately distinguish between PTSD and CPTSD. Further cross-cultural work is proposed to explore differences in PTSD and CPTSD across different countries with regard to prevalence, incidence, and predictors of PTSD and CPTSD. PMID:29372010

Water-quality control, monitoring and wastewater treatment in Lithuania 1950 to 1999.

PubMed

Cetkauskaite, A; Zarkov, D; Stoskus, L

2001-08-01

The Lithuanian water-management system developed on the basis of Soviet regulations in 1950-1990. Surface-water quality monitoring started in the 1950s, and the system was improved in the 1960s. Today, 48 rivers are being monitored using up to 70 parameters. Statutory monitoring of discharges started in 1962, wastewater standards were issued in 1957 and 1966, and then revised in 1996. Wastewater-treatment plants were built first in rural areas, in factories since the 1950s, and later in towns. Since 1991, large capacity municipal plants have been constructed with foreign assistance. Water quality has improved in some rivers since 1970, but Lithuania's main river, Nemunas, remains moderately polluted. The lower Nemunas is especially affected by discharges of municipal and industrial wastewater from Sovietsk and Neman (Russia), which account for half of the total loading. Hydrobiological data of 1994-1998 indicated the eutrophication of the Curonian Lagoon, and bacteriological pollution and blue-green algae blooms in the Baltic Sea north of Klaipeda.

Impact of beaver dams on abundance and distribution of anadromous salmonids in two lowland streams in Lithuania.

PubMed

Virbickas, Tomas; Stakėnas, Saulius; Steponėnas, Andrius

2015-01-01

European beaver dams impeded movements of anadromous salmonids as it was established by fishing survey, fish tagging and redd counts in two lowland streams in Lithuania. Significant differences in abundancies of other litophilic fish species and evenness of representation by species in the community were detected upstream and downstream of the beaver dams. Sea trout parr marked with RFID tags passed through several successive beaver dams in upstream direction, but no tagged fish were detected above the uppermost dam. Increase in abundances of salmonid parr in the stream between the beaver dams and decrease below the dams were recorded in November, at the time of spawning of Atlantic salmon and sea trout, but no significant changes were detected in the sections upstream of the dams. After construction of several additional beaver dams in the downstream sections of the studied streams, abundance of Atlantic salmon parr downstream of the dams decreased considerably in comparison with that estimated before construction.

PTSD and Complex PTSD: ICD-11 updates on concept and measurement in the UK, USA, Germany and Lithuania.

PubMed

Karatzias, Thanos; Cloitre, Marylene; Maercker, Andreas; Kazlauskas, Evaldas; Shevlin, Mark; Hyland, Philip; Bisson, Jonathan I; Roberts, Neil P; Brewin, Chris R

2017-01-01

The 11th revision to the World Health Organization's International Classification of Diseases (ICD-11) proposes two distinct sibling conditions: Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD). In this paper, we aim to provide an update on the latest research regarding the conceptual structure and measurement of PTSD and CPTSD using the International Trauma Questionnaire (ITQ) as per ICD-11 proposals in the USA, UK, Germany and Lithuania. Preliminary findings suggest that CPTSD is common in clinical and population samples, although there may be variations across countries in prevalence rates. In clinical samples, preliminary evidence suggests that CPTSD is a more commonly observed condition than PTSD. Preliminary evidence also suggests that the ITQ scores are reliable and valid and can adequately distinguish between PTSD and CPTSD. Further cross-cultural work is proposed to explore differences in PTSD and CPTSD across different countries with regard to prevalence, incidence, and predictors of PTSD and CPTSD.

Chlorogenic acid, rutin and hyperoside content in Fragaria vesca, F. viridis and F. moschata in Lithuania.

PubMed

Bagdonaite, Edita; Jakstas, Valdas; Raudonis, Raimondas; Janulis, Valdimaras

2013-01-01

In Lithuania, two species of the genus Fragaria L. (Rosaceae), F. vesca L. and F. viridis Weston, occur naturally in the wild and two others, F. moschata Weston and F. × ananassa Duchesne ex Rozier are found escaped from cultivation. The main objective of this study was to establish the variation pattern in the content of chlorogenic acid, rutin and hyperoside in leaves and fruits of the native Lithuanian species. In this work, the chemical polymorphisms of different Fragaria species were studied by growing plants side by side under the same cultivated field conditions. F. vesca fruits had the highest rutin (1.38 ± 0.19 mg g(-1) DM), hyperoside (0.69 ± 0.10 mg g(-1) DM) and chlorogenic acid (2.25 ± 0.34 mg g(-1) DM) content, followed by F. viridis and F. moschata. Our results showed that the leaves should be taken into account as important rutin and hyperoside contributors for strawberries.

Copy number variations and genetic admixtures in three Xinjiang ethnic minority groups

PubMed Central

Lou, Haiyi; Li, Shilin; Jin, Wenfei; Fu, Ruiqing; Lu, Dongsheng; Pan, Xinwei; Zhou, Huaigu; Ping, Yuan; Jin, Li; Xu, Shuhua

2015-01-01

Xinjiang is geographically located in central Asia, and it has played an important historical role in connecting eastern Eurasian (EEA) and western Eurasian (WEA) people. However, human population genomic studies in this region have been largely underrepresented, especially with respect to studies of copy number variations (CNVs). Here we constructed the first CNV map of the three major ethnic minority groups, the Uyghur, Kazakh and Kirgiz, using Affymetrix Genome-Wide Human SNP Array 6.0. We systematically compared the properties of CNVs we identified in the three groups with the data from representatives of EEA and WEA. The analyses indicated a typical genetic admixture pattern in all three groups with ancestries from both EEA and WEA. We also identified several CNV regions showing significant deviation of allele frequency from the expected genome-wide distribution, which might be associated with population-specific phenotypes. Our study provides the first genome-wide perspective on the CNVs of three major Xinjiang ethnic minority groups and has implications for both evolutionary and medical studies. PMID:25026903

Copy number variations and genetic admixtures in three Xinjiang ethnic minority groups.

PubMed

Lou, Haiyi; Li, Shilin; Jin, Wenfei; Fu, Ruiqing; Lu, Dongsheng; Pan, Xinwei; Zhou, Huaigu; Ping, Yuan; Jin, Li; Xu, Shuhua

2015-04-01

Xinjiang is geographically located in central Asia, and it has played an important historical role in connecting eastern Eurasian (EEA) and western Eurasian (WEA) people. However, human population genomic studies in this region have been largely underrepresented, especially with respect to studies of copy number variations (CNVs). Here we constructed the first CNV map of the three major ethnic minority groups, the Uyghur, Kazakh and Kirgiz, using Affymetrix Genome-Wide Human SNP Array 6.0. We systematically compared the properties of CNVs we identified in the three groups with the data from representatives of EEA and WEA. The analyses indicated a typical genetic admixture pattern in all three groups with ancestries from both EEA and WEA. We also identified several CNV regions showing significant deviation of allele frequency from the expected genome-wide distribution, which might be associated with population-specific phenotypes. Our study provides the first genome-wide perspective on the CNVs of three major Xinjiang ethnic minority groups and has implications for both evolutionary and medical studies.

HEROD: a human ethnic and regional specific omics database.

PubMed

Zeng, Xian; Tao, Lin; Zhang, Peng; Qin, Chu; Chen, Shangying; He, Weidong; Tan, Ying; Xia Liu, Hong; Yang, Sheng Yong; Chen, Zhe; Jiang, Yu Yang; Chen, Yu Zong

2017-10-15

Genetic and gene expression variations within and between populations and across geographical regions have substantial effects on the biological phenotypes, diseases, and therapeutic response. The development of precision medicines can be facilitated by the OMICS studies of the patients of specific ethnicity and geographic region. However, there is an inadequate facility for broadly and conveniently accessing the ethnic and regional specific OMICS data. Here, we introduced a new free database, HEROD, a human ethnic and regional specific OMICS database. Its first version contains the gene expression data of 53 070 patients of 169 diseases in seven ethnic populations from 193 cities/regions in 49 nations curated from the Gene Expression Omnibus (GEO), the ArrayExpress Archive of Functional Genomics Data (ArrayExpress), the Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC). Geographic region information of curated patients was mainly manually extracted from referenced publications of each original study. These data can be accessed and downloaded via keyword search, World map search, and menu-bar search of disease name, the international classification of disease code, geographical region, location of sample collection, ethnic population, gender, age, sample source organ, patient type (patient or healthy), sample type (disease or normal tissue) and assay type on the web interface. The HEROD database is freely accessible at http://bidd2.nus.edu.sg/herod/index.php. The database and web interface are implemented in MySQL, PHP and HTML with all major browsers supported. phacyz@nus.edu.sg. © The Author (2017). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

Dual Language = Saad Ahaah Sinil. A Navajo-English Dictionary. Revised Edition.

ERIC Educational Resources Information Center

Austin, Martha, Ed.; Lynch, Regina, Ed.

A dual-language Navajo-English dictionary provides a chart of the Navajo kinship system, a two-page map of the Navajo Nation, and English equivalents for Navajo words in 46 linguistic and cultural categories. Included are words for: races (Indian and other ethnic groups); Navajo clans; age groups; Navajo ceremonies; body parts; sickness; clothing;…

Embracing the World: Indigenous Educators Join Hands To Share Gifts

ERIC Educational Resources Information Center

Ambler, Marjane

2005-01-01

When a dozen education leaders met in Alberta, Canada, in August 2002, they felt the familiar thrill of history being made. They had come to form a worldwide organization for indigenous higher education, and their excitement sustained them for 12-hour days etching the road map for a new organization. Despite differences in language, ethnicity,…

Re-Contextualization of the Bologna Process in Lithuania

ERIC Educational Resources Information Center

Leisyte, Liudvika; Zelvys, Rimantas; Zenkiene, Lina

2015-01-01

The paper explores the implementation of selected Bologna action lines in Lithuanian higher education institutions (HEIs). The study is carried out from an organizational perspective on national re-contextualization, drawing upon sociological institutionalism. The Bologna process is likely to be normatively accepted by institutions in the context…

Ecosystem Services Assessment of the Nemunas River Delta

EPA Science Inventory

The concept of ecosystem services recognizes the services, and benefits, provided to people by ecosystems. The Nemunas River Delta, in Lithuania, is a valued area that can provide a range of services. We conducted a meta-analysis of existing studies done on the region to identify...

Progress in Decommissioning of Ignalina NPP Unit 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ancius, Darius; Krenevicius, Rimantas; Kutas, Saulius

2002-07-01

The aim of the paper is to present the Lithuanian legal framework regarding the nuclear safety in Decommissioning and Waste Management, and the progress in the Decommissioning Programme of the unit 1 of Ignalina Nuclear Power Plant (INPP). INPP is the only nuclear plant in Lithuania. It comprises two RBMK-1500 reactors. After Lithuania has restored its independence, responsibility for Ignalina NPP was transferred to the Republic of Lithuania. To ensure the control of the Nuclear Safety in Lithuania, The State Nuclear Power Safety Inspectorate (VATESI) was created on 18 October 1991, by a resolution of the Lithuanian Government. Significant workmore » has been performed over the last decade, aiming at upgrading the safety level of the Ignalina NPP with reference to the International standards. On 5 October 1999 the Seimas (Parliament) adopted the National Energy Strategy: It has been decided that unit 1 of Ignalina NPP will be closed down before 2005, The conditions and precise final date of the decommissioning of Unit 2 will be stated in the updated National Energy strategy in 2004. On 20-21 June 2000, the International Donors' Conference for the Decommissioning of Ignalina NPP took place in Vilnius. More than 200 Millions Euro were pledged of which 165 M funded directly from the European Union's budget, as financial support to the Decommissioning projects. The Decommissioning Program encompasses legal, organizational, financial and technical means including the social and economical impacts in the region of Ignalina. The Program is financed from International Support Fund, State budget, National Decommissioning Fund of Ignalina NPP and other funds. Decommissioning of Ignalina NPP is subject to VATESI license according to the Law on Nuclear Energy. The Government established the licensing procedure in the so-called 'Procedure for licensing of Nuclear Activities'; and the document 'General Requirements for Decommissioning of the Ignalina NPP' has been issued by VATESI. A very important issue is the technical support to VATESI and the Lithuanian TSO's (Technical Support Organisations) in their activities within the licensing process related to the Decommissioning of INPP. This includes regulatory assistance in the preparation of decommissioning and radioactive waste management regulatory documents, and technical assistance in the review of the safety case presented by the operator. The Institute for Radioprotection and Nuclear Safety (IRSN, France) and the French Nuclear Safety Authority (DSIN) as well as Swedish International Project (SIP) are providing their support to VATESI in these areas. (authors)« less

PREFACE: 5th Baltic Conference on Silicate Materials

NASA Astrophysics Data System (ADS)

Mezinskis, G.; Bragina, L.; Colombo, P.; Frischat, G. H.; Grabis, J.; Greil, P.; Deja, J.; Kaminskas, R.; Kliava, J.; Medvids, A.; Nowak, I.; Siauciunas, R.; Valancius, Z.; Zalite, I.

2011-12-01

Logo This Volume of IOP Conference Series: Materials Science and Engineering presents a selection of the contributions to the 5th Baltic Conference on Silicate Materials (BaltSilica2011) held at Riga Technical University, Riga, Latvia from 23-25 May 2011. The conference was organized by Riga Technical University (Latvia) and Kaunas University of Technology (Lithuania). The series of Baltic conferences on silicate materials was started since 2004: the first conference was held in Riga, Latvia, 2004; the second conference was held in Kaunas, Lithuania 2005; the third was held again in Riga, Latvia, 2007, and the fourth was held in Kaunas, Lithuania 2009. BaltSilica 2011 was attended by around 50 participants from Latvia, Lithuania, Estonia, Germany, Poland, Italy, France, Ukraine and Russia. In comparison with previous silicate materials conferences, the broadening of participating countries is an indication of the interest of scientists, engineers and students to exchange research ideas, latest results, and to find new research topics for cooperation in the fields of silicate, high temperature materials, and inorganic nanomaterials. The scientific programme included 8 invited plenary lectures 23 oral presentations and 25 posters [1]. Scientific themes covered in the conference and in this special issue: Natural and Artificial Stone Materials; Traditional and New Ceramic and Glass-Like Materials; Nanoparticles and Nanomaterials. This volume consists of 23 selected proceeding papers. The Editor of this special issue is grateful to all the contributors to BaltSilica 2011. I am also very grateful to the scientific committee, the local organizing committee, the session chairs, the referees who refereed the submitted articles to this issue, and to students from the Department of Silicate, High Temperature and Inorganic Nanomaterials Technology of the Riga Technical University who ensured the smooth running of the conference. Particular thanks goes to eight plenary speakers who provided interesting findings and thoughtful overviews in the scientific themes of the conference. Special thanks go to Prof., Dr.rer.nat. Günther Heinz Frischat (Germany) who encouraged and supported the organization of these scientific meetings from the very first BaltSilica conferences. With warm regards and best wishes for the next BaltSilica conference. The Conference Chairman Gundars Mezinskis Reference [1] Baltic Conference on Silicate Materials. Book of abstracts of the 5th Baltic Conference on Silicate Materials BaltSilica 2011 : 23-25 May 2011, Riga, Latvia ed G Mezinskis, G Sedmale, J Setina, I Sperberga, L Krage, I Pavlovska, D Andersone (Riga: RTU Publishing House) p 94

Landscape Heterogeneity mapping for Access to Tribal health care in Nilgiris District of Tamil Nadu, India

NASA Astrophysics Data System (ADS)

Brindha, B.; Prashanthi Devi, M.

2014-11-01

The Nilgiris district in Tamilnadu has a rich biodiversity in terms of flora, fauna and ethnic population. The district is basically a mountainous region, situated at an elevation of 2000 to 2,600 meters above MSL and constituting of several hill and Steep Mountain valleys. This region houses six tribes who are mainly forest dwellers and live in close settlements depending on the forest resources for their livelihood. The Tribes of Nilgiris have been diagnosed and monitored for Sickle cell Anemia which is a disease of major concern among these ethnic populations. This genetic disorder developed due to the sickling of Red Blood Cells has increased during the past few decades. The Tribes, as they live in close encounter with the forest regions and have strict social cultural barriers, face difficulty in availing treatment or counseling from the Sickle Cell Research Center (SCRC) and other NGOs like NAWA and AHWINI in the region. It was observed that many factors such as landscape terrain, climatic conditions and improper roads tend to hinder the access to appropriate health care. The SCRC in Gudalur region is a facility established to monitor the disease cases inspite of these influencing factors. On analyzing the year bound age wise classification among male and female patients, certain dropouts in cases were observed which may be due to inaccessible condition or migration of the patient. In our study, Landscape heterogeneity mapping for different climatic seasons was done in ArcGIS 10.1. For this, contour and terrain maps, road networks and villages were prepared and factors that determine Terrain Difficulty were assessed. Vegetation mapping using IRS satellite images for the study region was attempted and associated with the landscape map. A risk analysis was proposed based on terrain difficulty and access to the nearest Health care Center. Based on this, the above factors alternate routes were suggested to access the difficult areas.

COMPARISON OF AIR POLLUTANT EMISSIONS FROM THE COMBUSTION OF ORIMULSION AND OTHER FUELS

EPA Science Inventory

The paper gives results of inhouse emissions testing and a literature review relating to Orimulsion, an emulsion of Venezuelan bitumen, water, and a proprietary surfactant, being used as a fuel for utilities in Canada, China, Denmark, Italy, Japan, and Lithuania, primarily as a r...

Internationalisation of Higher Education and Nation Building: Resolving Language Policy Dilemmas in Lithuania

ERIC Educational Resources Information Center

Bulajeva, Tatjana; Hogan-Brun, Gabrielle

2014-01-01

Our paper discusses trends and challenges faced by Lithuanian Higher Education (HE) internationalisation policy processes in the context of European and global internationalisation tendencies. Using 2001-2011 EU mobility statistics and data from recent HE Lithuanian strategic programmes aimed at promoting the internationalisation of university…

NATO CCMS PILOT STUDY ON CLEAN PRODUCTS AND PROCESSES -(PHASE I) - 2002 ANNUAL REPORT

EPA Science Inventory

The annual report summarizes the activities of the NATO CCMS Pilot Study on clean products and processes for 2002, including the proceedings of the 2002 annual meeting held in Vilnius, Lithuania. The report presents a wealth of information on cleaner production activities in ove...

Goals of Quality in Doctoral Studies and Forecasted Outcomes

ERIC Educational Resources Information Center

Zelvys, Rimantas

2007-01-01

This article discusses the quality assurance policy of doctoral studies implemented in Lithuania and its probable outcomes are forecasted. In scientific literature the quality of education is commonly defined as a holistic phenomenon composed of the quality of initial conditions, quality of process and quality of outputs. The accomplished document…

Research on Mobile Learning Activities Applying Tablets

ERIC Educational Resources Information Center

Kurilovas, Eugenijus; Juskeviciene, Anita; Bireniene, Virginija

2015-01-01

The paper aims to present current research on mobile learning activities in Lithuania while implementing flagship EU-funded CCL project on application of tablet computers in education. In the paper, the quality of modern mobile learning activities based on learning personalisation, problem solving, collaboration, and flipped class methods is…

Bush vs. Obama Detainee Policy Post-9/11: An Assessment

DTIC Science & Technology

2010-01-01

detainees, including Abd al- Rahim al-Nashiri, the accused architect of al-Qaeda’s bombing of the Navy destroyer USS Cole in Yemen in 2000, were to be...foreign inmates absent a formal agreement. Lithuania began talks with the United States about accepting prisoners from Guantanamo, and the European

Biogeographical ancestry and race.

PubMed

Gannett, Lisa

2014-09-01

The use of racial and ethnic categories in biological and biomedical research is controversial-for example, in the comparison of disease risk in different groups or as a means of making use of or controlling for population structure in the mapping of genes to chromosomes. Biogeographical ancestry (BGA) has been recommended as a more accurate and appropriate category. BGA is a product of the collaboration between biological anthropologist Mark Shriver from Pennsylvania State University and molecular biologist Tony Frudakis from the now-defunct biotechnology start-up company DNAPrint genomics, Inc. Shriver and Frudakis portray BGA as a measure of the 'biological', 'genetic', 'natural', and 'objective' components of race and ethnicity, what philosophers of science would call a natural kind. This paper argues that BGA is not a natural kind that escapes social and political connotations of race and ethnicity, as Shriver and Frudakis and other proponents believe, but a construction that is built upon race-as race has been socially constructed in the European scientific and philosophical traditions. More specifically, BGA is not a global category of biological and anthropological classification but a local category shaped by the U.S. context of its production, especially the forensic aim of being able to predict the race or ethnicity of an unknown suspect based on DNA found at the crime scene. Therefore, caution needs to be exercised in the embrace of BGA as an alternative to the use of racial and ethnic categories in biological and biomedical research. Copyright © 2014 Elsevier Ltd. All rights reserved.

From Pipelines to Partnerships: A Synthesis of Research on How Diverse Families, Schools, and Communities Support Children's Pathways Through School

ERIC Educational Resources Information Center

Cooper, Catherine R.; Chavira, Gabriela; Mena, Dolores D.

2005-01-01

This article maps recent progress on 5 key questions about "the academic pipeline problem" of different rates of persistence through school among ethnically diverse students across the nation. The article shows the complementary development of the Overlapping Spheres of Influence Theory and Sociocultural Theory and aligns concepts and measures…

Pharmacogenetics: Implications of Race and Ethnicity on Defining Genetic Profiles for Personalized Medicine

PubMed Central

Ortega, Victor E.; Meyers, Deborah A.

2014-01-01

Pharmacogenetics is being used to develop personalized therapies specific to individuals from different ethnic or racial groups. Pharmacogenetic studies to date have been primarily performed in trial cohorts consisting of non-Hispanic whites of European descent. A “bottleneck” or collapse of genetic diversity associated with the first human colonization of Europe during the Upper Paleolithic period, followed by the recent mixing of African, European, and Native American ancestries has resulted in different ethnic groups with varying degrees of genetic diversity. Differences in genetic ancestry may introduce genetic variation which has the potential to alter the therapeutic efficacy of commonly used asthma therapies, for example β2-adrenergic receptor agonists (beta agonists). Pharmacogenetic studies of admixed ethnic groups have been limited to small candidate gene association studies of which the best example is the gene coding for the receptor target of beta agonist therapy, ADRB2. Large consortium-based sequencing studies are using next-generation whole-genome sequencing to provide a diverse genome map of different admixed populations which can be used for future pharmacogenetic studies. These studies will include candidate gene studies, genome-wide association studies, and whole-genome admixture-based approaches which account for ancestral genetic structure, complex haplotypes, gene-gene interactions, and rare variants to detect and replicate novel pharmacogenetic loci. PMID:24369795

Generalizability of Associations from Prostate Cancer GWAS in Multiple Populations

PubMed Central

Waters, Kevin M.; Le Marchand, Loic; Kolonel, Laurence N.; Monroe, Kristine R.; Stram, Daniel O.; Henderson, Brian E.; Haiman, Christopher A.

2010-01-01

Genome-wide association studies have identified multiple common alleles associated with prostate cancer risk in populations of European ancestry. Testing these variants in other populations is needed to assess the generalizability of the associations, and may guide fine-mapping efforts. We examined 13 of these risk variants in a multiethnic sample of 2,768 incident prostate cancer cases and 2,359 controls from the Multiethnic Cohort (MEC; African Americans, European Americans, Latinos, Japanese Americans and Native Hawaiians). We estimated ethnic-specific and pooled odds ratios and tested for ethnic heterogeneity of effects using logistic regression. In ethnic-pooled analyses, 12 of the 13 variants were positively associated with risk, with statistically significant associations (p<0.05) noted with 6 variants (odds ratio, 95% confidence interval): JAZF1, rs10486567, 1.23(1.12–1.35); Xp11.2, rs5945572, 1.31(1.13–1.51); HNF1B, rs4430796, 1.15(1.06–1.25); MSMB, rs10993994, 1.13(1.04–1.23); 11q13.2, rs7931342, 1.13(1.03–1.23); 3p12.1, rs2660753, 1.11(1.01–1.21); SLC22A3, rs9364554, 1.10(1.00–1.21); CTBP2, rs12769019, 1.11(0.99–1.25); HNF1B, rs11649743, 1.10(0.99–1.22); EHBP1, rs721048, 1.08(0.94–1.25); KLK2/3, rs2735839, 1.06(0.97–1.16); 17q24.3, rs1859962, 1.04(0.96–1.13); and LMTK2, rs6465657, 0.99(0.89–1.09). Significant ethnic heterogeneity of effects was noted for 4 variants (EHBP1, phet = 3.9×10−3; 11q13, phet = 0.023; HNF1B (rs4430796), phet = 0.026; and KLK2/3, phet = 2.0×10−3). Although power was limited in some ethnic/racial groups due to variation in sample size and allele frequencies, these findings suggest that a large fraction of prostate cancer variants identified in populations of European ancestry are global markers of risk. For many of these regions, fine-mapping in non-European samples may help localize causal alleles and better determine their contribution to prostate cancer risk in the population. PMID:19318432

An Initial Study of the Diagnostic Utility of the Emotional and Behavioural Screener in Lithuania

ERIC Educational Resources Information Center

Sointu, Erkko; Lambert, Matthew C.; Nordness, Philip D.; Geležiniene, Renata; Epstein, Michael H.

2018-01-01

In schools, screening is an effective method to identify students at-risk for emotional and behavioural disorders. Several intervention programmes such as Positive Behaviour Interventions and Supports, Response to Intervention, and Multi-tiered Systems of Supports call for the use of psychometrically sound screening instruments. This study…

Lithuanian Educators' Experiences of Norwegian Early Childhood Education and Care during a Short Study Trip

ERIC Educational Resources Information Center

Sadownik, Alicja R.; Baraldsnes, Dziuginta; Kalgraf, Solveig

2017-01-01

This paper presents an analysis of how educators from Lithuania experienced the Norwegian ECEC during a short study trip. The research results are informed by the theory of Practice Architecture [7, 8] that describes educational practices using the concepts of "sayings," "doings," and "relatings." "Sayings"…

Congratulating the Baltic nations of Estonia, Latvia, and Lithuania on the 20th anniversary of their declarations on the restoration of independence from the Soviet Union.

THOMAS, 111th Congress

Rep. Shimkus, John [R-IL-19

2010-04-26

Senate - 12/08/2010 Received in the Senate and referred to the Committee on Foreign Relations. (All Actions) Tracker: This bill has the status Agreed to in HouseHere are the steps for Status of Legislation:

Educational Choice Regarding Technical Education: Research with Case Study

ERIC Educational Resources Information Center

Kacerauskas, Tomas; Šaparauskas, Jonas

2017-01-01

In first part, the models, theories, mechanisms and presumptions, as well as the ideas of educational choice discourse have been scrutinized. In the second part, the survey on educational choice at Vilnius Gediminas Technical University, Lithuania has been presented. The methodology used in this research is a survey of respondents and survey…

Knowledge of ICT of Secondary School Graduates

ERIC Educational Resources Information Center

Valavicius, Eugenijus; Babravicius, Kestutis

2012-01-01

The paper analyses the results of the computer literacy survey conducted among the 11th and 12th form students in gymnasiums and secondary schools in Lithuania. The basis for the questionnaire was taken from previous surveys carried out in Vilnius Pedagogical University. The questionnaire is divided into five topics, such as computer hardware and…

The Practice of Media Education: International Research on Six European Countries

ERIC Educational Resources Information Center

Parola, Alberto; Ranieri, Maria

2011-01-01

This paper presents and discusses the results of OnAir, a European project on Media Education funded by the European Commission. This two-year project aimed at collecting, documenting, and developing media education practices across Europe, especially in Belgium, Bulgaria, Italy, Lithuania, Poland, and Romania. In particular, the paper focuses on…

Student Internships in Lithuania: A Stakeholder Perspective on Management and Economics Programmes

ERIC Educational Resources Information Center

Kaminskiene, Lina; Rutkiene, Aušra

2012-01-01

The article discusses the practice of internships in Lithuanian higher education in the context of changes and challenges to educational reforms, particularly in the enhancement of relations with the labour market and related stakeholders. Higher education institutions are grappling with the changing conception, and duration, of the internship.…

International Models and Domestic Translations? The Case of University Governing Boards in Romania and Lithuania

ERIC Educational Resources Information Center

Králiková, Renáta

2015-01-01

In the early 2000s, several post-communist countries launched reforms of university management and governance marked by the influence of a "modernization agenda" for higher education governance, which was promoted by the World Bank, the OECD and the European Commission. However, this "modernization agenda" was employed…

Qualifications at Level 5: Progressing in a Career or to Higher Education. Working Paper No 23

ERIC Educational Resources Information Center

Grm, Slava Pevec; Bjørnåvold, Jens

2014-01-01

This study addresses qualifications at level 5 of the European qualifications framework (EQF) in 15 countries (Belgium (Flanders), the Czech Republic, Denmark, Estonia, Ireland, France, Croatia, Latvia, Lithuania, Luxembourg, Malta, the Netherlands, Austria, Portugal, the United Kingdom (EWNI and Scotland) that had linked their national…

Teachers as Informal Learners: Workplace Professional Learning in the United States and Lithuania

ERIC Educational Resources Information Center

Jurasaite-Harbison, Elena; Rex, Lesley A.

2013-01-01

This study demonstrates the understandings that result from teachers' explanations of how they learn when they encounter everyday situations that evoke their learning. The study renders these explanations as a framework for further research on teacher workplace learning in informal settings. The framework emerged from a constant-comparative…

Subjective Vitality and Patterns of Acculturation: Four Cases

ERIC Educational Resources Information Center

Ehala, Martin; Vedernikova, Elena

2015-01-01

The article presents a comparative analysis of the subjective vitalities (SVs) of the minority groups of Latvia (Russian-speakers), Lithuania (Russian-speakers and Poles) and Mari El (Maris) in the Russian Federation, with a particular focus on the Mari case. The same extended version of the SV questionnaire was used in quantitative surveys in all…

Language Policy and the Internationalization of Higher Education in the Baltic Countries

ERIC Educational Resources Information Center

Kaša, Rita; Mhamed, Ali Ait Si

2013-01-01

In the framework of the internationalization and globalization of higher education and competition for international students, the paper examines how language policy in higher education shapes the provision of study programs in Estonia, Latvia, and Lithuania. It concludes that study programs in the Baltic states mostly follow the convention of a…

Central and Eastern Europe: Vocational Education and Training in Transition.

ERIC Educational Resources Information Center

Bertrand, Olivier

1995-01-01

Analysis of recent developments in vocational education and training in the countries of Central and Eastern Europe brings out certain common problems. On the economic level, Hungary, Poland, Estonia, and Lithuania are undergoing a profound crisis. Consequences for training have included the closing of many company schools or workshops, absence of…

Psycho-Semantics of Management Constructs: Expression of Democracy among Schoolteachers

ERIC Educational Resources Information Center

Saparnis, Gintaras

2006-01-01

Purpose: The purpose of this research was to disclose the psycho-semantics of the opinions held by school educators in Lithuania on the expression of democracy in education management. Methodology: A non-standardized questionnaire asked teachers the open-ended question: "Are there any manifestations of democracy in your school? If yes (or…

Examining Trends in Parent-Child Communication in Europe over 12 Years

ERIC Educational Resources Information Center

Tabak, Izabela; Mazur, Joanna; Granado Alcon, Maria del Carmen; Orkenyi, Agota; Zaborskis, Apolinaras; Aasvee, Katrin; Moreno, Carmen

2012-01-01

The aim of this study was to analyze changes in communication with parents about matters of concern to 11- and 13-year olds. Health Behaviour in School-aged Children (HBSC) surveys conducted in Austria, the Czech Republic, Denmark, Estonia, Finland, France, Germany, Hungary, Lithuania, Latvia, Norway, Poland, Russia, Slovakia, Sweden, and…

Adolescents' Intentional Self-Mutilation

ERIC Educational Resources Information Center

Laskite, A.; Laskene, S.

2011-01-01

In Lithuania, suicide is among the top three causes of death; between twenty and thirty-three school-age children take their own lives every year, and the overwhelming majority of adolescents do not seek help in connection with situations that prompt them to engage in self-mutilation. Research indicates adolescents think that if more attention is…

Economic and Educational Correlates of TIMSS Results

ERIC Educational Resources Information Center

Mikk, Jaan

2005-01-01

The good knowledge of the correlates of educational achievement highlights the ways to the efficient use of economic and human capital in raising the efficiency of education. The present paper investigates the correlates and compares the values of the correlates for the Republic of Lithuania with the average international values. The data for the…

Great Expectations? Variation in Educational Plans of Students in Post-Socialist Eastern Europe

ERIC Educational Resources Information Center

Chykina, Volha; Chung, Hee Jin; Bodovski, Katerina

2016-01-01

Using all available waves of the Trends in International Mathematics and Science Study (TIMSS) from 1995 to 2011, this study examines the factors influencing educational expectations of students in five Eastern European countries (Hungary, Lithuania, the Russian Federation, Romania, and Slovenia). We consistently find across countries and waves…

Issues and Challenges for Small Countries in Attracting and Hosting International Students: The Case of Lithuania

ERIC Educational Resources Information Center

Urbanovic, Jolanta; Wilkins, Stephen; Huisman, Jeroen

2016-01-01

The spread of the neo-liberal ideology internationally has encouraged increased marketisation of higher education systems right around the world. With marketisation promoting competition, efficiency and revenue generation, many countries have begun to recruit more foreign students. Higher education has moved towards becoming a profitable commodity…

Lithuanian University Students' Knowledge of Biotechnology and Their Attitudes to the Taught Subject

ERIC Educational Resources Information Center

Lamanauskas, Vincentas; Makarskaite-Petkeviciene, Rita

2008-01-01

The impact of genetic engineering on peoples' everyday life has become present reality. In order to establish the level of the available schoolchildren and university students' knowledge of biotechnology, various investigations have been conducted. However, the current situation in Lithuania remains unclear. A total of 287 students--pre-service…

From the Analysis of Work-Processes to Designing Competence-Based Occupational Standards and Vocational Curricula

ERIC Educational Resources Information Center

Tutlys, Vidmantas; Spöttl, Georg

2017-01-01

Purpose: This paper aims to explore methodological and institutional challenges on application of the work-process analysis approach in the design and development of competence-based occupational standards for Lithuania. Design/methodology/approach: The theoretical analysis is based on the review of scientific literature and the analysis of…

FSU/Eastern Europe: Russia spearheads small upturn

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-08-01

The paper discusses the political and legal scene in Russia, domestic restructuring, exploration, drilling, development by Western companies and by Russian companies, and production. Exploration and development in Azerbaijan, Kazakhstan, Turkmenistan, Ukraine, Armenia, Belarus, Georgia, Kyrgyzstan, Latvia, Lithuania, Moldova, Tajikistan, Uzbekistan, Albania, Bulgaria, Croatia, Czech Republic, Hungary, Poland, Romania, Slovakia, Slovenia, and Serbia are also discussed.

Resources for development of training in public health and health managment in Eastern Europe: the Kaunas experience.

PubMed

Kalediene, Ramune

2002-01-01

The aim of this paper is to review the resources and steps required for development and evaluation of training in public health and management of public health as experienced in Kaunas University of Medicine, Lithuania. The transition from Departments of Social Medicine and Hygiene to a Faculty of Public Health of international standards requires a process of adaptation and development of human resources more than physical facilities. After restoration of independence in 1990, rapid development of training in public health was started in Lithuania. Great support was provided by the international projects Baltic Rim Partnership for Public Health (BRIMHEALTH) and European Union Trans-European Mobility Scheme for University Students (TEMPUS). Undergraduate and postgraduate training programs were successfully implemented in the Faculty of Public Health, Kaunas University of Medicine. Lithuanian experience could serve as an example of success and pitfalls in training a critical mass of professionals who should act as powerful advocates for health, promoting analysis, continuity and success of public health interventions, and health care reforms in countries in transition.

Inequalities in mortality by marital status during socio-economic transition in Lithuania.

PubMed

Kalediene, R; Petrauskiene, J; Starkuviene, S

2007-05-01

To analyse the changes in mortality inequalities by marital status over the period of socio-economic transition in Lithuania and to estimate the contribution of major causes of death to marital-status differences in overall mortality. A survey based on routine mortality statistics and census data for 1989 and 2001 for the entire country. The proportion of married population has declined over the past decade. Widowed men and never married women were found to be at highest risk of mortality throughout the period under investigation. Although inequalities have not grown considerably, mortality rates have increased significantly for divorced populations and for never married men, widening the mortality gap. Cardiovascular diseases contributed most to excess mortality of never married and divorced men, as well as all unmarried groups of women. The excess mortality of widowed men from external causes was greatest in 2001. Marriage can be considered as a health protecting factor, particularly in relation to mortality from cardiovascular diseases and external causes. Local and national policies aimed at health promotion must focus primarily on improving the position of unmarried groups and providing psychological support.

Awareness and practice of patient's rights law in Lithuania

PubMed Central

Ducinskiene, Danute; Vladickiene, Jurgita; Kalediene, Ramune; Haapala, Irja

2006-01-01

Background Patient's rights law is intended to secure good medical practice, but it can also serve to improve understanding between patients and medical staff if both were aware of their rights. Methods Awareness and practice of the new patient's rights law in Lithuanian health care institutions was explored through a survey of 255 medical staff and 451 patients in the four Kaunas city medical units in 2002. Participation rates were 74% and 66%, respectively. Results Majority of the medical staff (85%) and little over one half of the patients (56%) had heard or read about the Law on Patient's Rights (p < 0.001). Only 50% of professionals compared to 69% of patients thought information for patients about diagnosis, treatment results and alternative treatments is necessary (p < 0.001). A clear discrepancy was indicated between physicians informing the patients (80% – 98% of physicians) and patients actually knowing (37% – 54%) their treatment prognosis, disease complications or possible alternative treatment methods. Conclusion These results suggest a need for awareness-raising among patients to improve the practical implementation of the Patient's Rights Law in Lithuania. PMID:16948855

Registering the Human Terrain: A Valuation of Cadastre

DTIC Science & Technology

2008-01-01

which is also an intelligence topic of increasing salience. Ethno-linguistic maps, such as Figure 1 depicting languages spoken or religions ...Desert] to Congo, tens of thousands of people are at war. You might think these struggles are about religion , or ethnicity, or even political diff...Nazi pseudoscience responsible for 70 million deaths. Academia quickly distanced itself from environmental determinism, the theory behind Geopolitik

South Asian ethnicity is associated with a lower prevalence of atrial fibrillation despite greater prevalence of established risk factors: a population-based study in Bradford Metropolitan District.

PubMed

Gillott, Richard Geoffrey; Willan, Kathryn; Kain, Kirti; Sivananthan, Uduvil Mohanaraj; Tayebjee, Muzahir Hassan

2017-03-01

Previous studies indicate that South Asians (SAs) may have a reduced risk of developing atrial fibrillation (AF) despite having a higher prevalence of traditional cardiovascular risk factors. This observational study was designed to explore the relative differences between SAs and Whites in a well-defined, multi-ethnic population with careful consideration of traditional cardiovascular risk factors that are thought to contribute to the development of AF. Anonymized data from 417 575 adults were sourced from primary care records within Bradford Metropolitan District, UK. Atrial fibrillation diagnosis was indicated by the presence on the AF Quality Outcomes Framework register. Self-reported ethnicity was mapped to census ethnic codes. The age-standardized prevalence rates of AF were calculated for comparison between the White and SA populations; our study sample presented relative proportions of 2.39 and 0.4%. Multivariable logistic regression analysis was performed to estimate the odds of developing AF given SA ethnicity. Adjustment for age, sex, and established risk factors found a 71% reduction in odds of AF in SAs when compared with Whites [odds ratio (OR): 0.29, 95% confidence interval (CI): 0.26-0.32]. When stratified by ethnicity, analyses revealed significantly different odds of AF for patients with diabetes; diabetes was not associated with the development of AF in the SA population (0.81, 95% CI: 0.63-1.05). This study, in a multi-ethnic population, presents ethnicity as a predictor of AF in which prevalence is significantly lower in SAs when compared with Whites. This is despite SAs having a higher frequency of established risk factors for the development of AF, such as ischaemic heart disease, heart failure, hypertension, and type 2 diabetes. These findings are consistent with previous literature and add weight to the need for further investigation, although this is the first study to investigate the differential associations of individual risk factors with development of AF. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2016. For permissions please email: journals.permissions@oup.com.

[Irrational drug use in Siauliai, Panevezys and Utena counties of Lithuania].

PubMed

Maciulaitis, Romaldas; Janusonis, Tomas

2003-01-01

In our study, we aimed to investigate the irrational use of the reimbursed drugs in some counties of Lithuania in 2001 by investigating the viewpoints of the physicians to the problems of the irrational pharmacotherapy, possible causes and solutions of them. This investigation was designed as a qualitative structured questionnaire. The study was composed of two stages. The personal health records of 2001 of Siauliai, Panevezys and Utena counties residents were analyzed and the cases of irrational drug use were selected, examined and verified during the first stage. There were 318 personal health records analyzed and 111 cases of irrational drug use verified. The 23 problems of irrational pharmacotherapy were distinguished and classified according to the responsibilities. The viewpoints of the physicians to the problems of the irrational pharmacotherapy were confirmed and analyzed during the second stage of the study. Thirty-one physicians were interviewed and responses summarized. 1. The irrational drug use took place in Siauliai, Panevezys and Utena counties of Lithuania in 2001. 2. Twenty-three types of problems of irrational pharmacotherapy can be distinguished. They can be classified into the 3 main levels according to the responsibility: the level of the administration (institution), the physician and the patient; other problems can be distinguished separately. 3. The most frequently specified by physicians possible reasons of the irrational drug use were the lack of information, the overcharge of the physician and the lack of the qualification. 4. The most frequently specified possible solutions of the irrational drug use by physicians were the growth of qualification, the establishment of the algorithms and the increase of the time spent per patient. 5. There was noticed particular tendency at the level of the physicians: physicians eliminated their responsibility at this level and related the problems with other levels--the levels of the administration (institution) and the patient.

The prevalence of type 1 diabetes mellitus among 15-34-year-aged Lithuanian inhabitants during 1991-2010.

PubMed

Ostrauskas, Rytas

2015-04-01

To summarize the data on the prevalence of type 1 diabetes mellitus among 15-34-year-aged Lithuania inhabitants (1991-2010). New prevalent cases consist of growing-up patients with diabetes onset in childhood, i.e., up to 14 years, new onset 15-34-year-aged type 1 diabetic patients Lithuanian inhabitants, and immigrants. The data on type 1 diabetes was collected with the help of general practitioners and regional endocrinologists in Lithuania. On 31 December 1991, there were 1202 adolescent and adult 15-34-year-aged patients with type 1 diabetes mellitus or 103.59 per 100,000 inhabitants of the same age group (95% Poisson CI 97.90-109.62), and at the end of 2010 - 1533 or 187.80 (178.63-197.44), respectively in Lithuania. During 19-year period the mean increase of type 1 diabetic patients was 1.25±1.94% per year or 1.47±2.74 per 100,000 inhabitants per mean year of the study period (for males 1.42±2.14% or 1.69±3.05/100,000 and for females 1.05±1.99%, or 1.24±2.92/100,000). Regression-based linear trends showed that the prevalence of type 1 diabetes mellitus in 15-34-year-age group had a tendency to increase among males (r=0.953; p<0.001) and females (r=0.970; p<0.001). The age adjusted prevalence frequencies for males and females in 1991 were correspondingly 102.81/100,000 and 104.55/100,000, and in 2010 - 193.75 and 182.01. The prevalence of type 1 diabetes mellitus among 15-34-year-age males and females had a tendency to increase during 1991-2010. Copyright © 2014 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.

Power politics: National energy strategies of the nuclear newly independent states of Armenia, Lithuania and Ukraine

NASA Astrophysics Data System (ADS)

Sabonis-Chafee, Theresa Marie

The successor states of Armenia, Lithuania and Ukraine arrived at independence facing extraordinary challenges in their energy sectors. Each state was a net importer, heavily dependent on cheap energy supplies, mostly from Russia. Each state also inherited a nuclear power complex over which it had not previously exercised full control. In the time period 1991--1996, each state attempted to impose coherence on the energy sector, selecting a new course for the pieces it had inherited from a much larger, highly integrated energy structure. Each state attempted to craft national energy policies in the midst of severe supply shocks and price shocks. Each state developed institutions to govern its nuclear power sector. The states' challenges were made even greater by the fact that they had few political or economic structures necessary for energy management, and sought to create those structures at the same time. This dissertation is a systematic, non-quantitative examination of how each state's energy policies developed during the 1991--1996 time period. The theoretical premise of the analysis (drawn from Statist realism) is that systemic variables---regional climate and energy vulnerability---provide the best explanations for the resulting energy policy decisions. The dependent variable is defined as creation and reform of energy institutions. The independent variables include domestic climate, regional climate, energy vulnerability and transnational assistance. All three states adopted rhetoric and legislation declaring energy a strategic sector. The evidence suggests that two of the states, Armenia and Lithuania, which faced tense regional climates and high levels of energy vulnerability, succeeded in actually treating energy strategically, approaching energy as a matter of national security or "high politics." The third state, Ukraine, failed to do so. The evidence presented suggests that the systemic variables (regional climate and energy vulnerability) provided a more favorable environment for Ukraine, one in which the state attempted reform of the sector, but not as a concerted national security issue.

The prevalence of self-reported underuse of medications due to cost for the elderly: results from seven European urban communities.

PubMed

Stankuniene, Aurima; Stankunas, Mindaugas; Avery, Mark; Lindert, Jutta; Mikalauskiene, Rita; Melchiorre, Maria Gabriella; Torres-Gonzalez, Francisco; Ioannidi-Kapolou, Elisabeth; Barros, Henrique; Savickas, Arūnas; Radziunas, Raimondas; Soares, Joaquim J F

2015-09-26

The aim of this study was to evaluate the prevalence of self-reported underuse of medications due to procurement costs amongst older persons from seven European urban communities. The data were collected in a cross-sectional study ("ABUEL, Elder abuse: A multinational prevalence survey") in 2009. Randomly selected people aged 60-84 years (n = 4,467) from seven urban communities: Stuttgart (Germany), Athens (Greece), Ancona (Italy), Kaunas (Lithuania), Porto (Portugal), Granada (Spain) and Stockholm (Sweden) were interviewed. Response rate - 45.2%. Ethical permission was received in each country. The results indicate that 3.6% (n = 162) of the respondents self-reported refraining from buying prescribed medications due to cost. The highest prevalence of this problem was identified in Lithuania (15.7%, n = 99) and Portugal (4.3%, n = 28). Other countries reported lower percentages of refraining from buying medications (Germany - 2.0%, Italy - 1.6%, Sweden - 1.0%, Greece - 0.6%, Spain - 0.3%). Females refrained more often from buying medications than males (2.6% vs. 4.4%, p < 0.0001). The prevalence of this refraining tended to increase with economic hardship. These differences between countries can be only partly described by the financing of health-care systems. In spite of the presence of cost reimbursement mechanisms, patients need to make co-payments (or in some cases to pay the full price) for prescribed medications. This indicates that the purchasing power of people in 10.1186/s12913-015-1089-4 the particular country can play a major role and be related with the economic situation in the country. Lithuania, which has reported the highest refrain rates, had the lowest gross domestic product (at the time of conducting this study) of all participating countries in the study. Refraining from buying the prescribed medications due to cost is a problem for women and men in respect to ageing people in Europe. Prevalence varies by country, sex, and economic hardship.

Prevalence of overweight/obesity in relation to dietary habits and lifestyle among 7-17 years old children and adolescents in Lithuania.

PubMed

Smetanina, Natalija; Albaviciute, Edita; Babinska, Veslava; Karinauskiene, Lina; Albertsson-Wikland, Kerstin; Petrauskiene, Ausra; Verkauskiene, Rasa

2015-10-01

Until recently increasing prevalence of overweight and obesity among pediatric population in Europe and worldwide contributes to major well-known risks for metabolic consequences in later life. The aim of this study was to determine the prevalence of overweight/obesity among children and adolescents in Lithuania and assess its association with energy balance related behaviors as well as familial demographic and socioeconomic factors. Cross-sectional study included 3990 7-17 years old schoolchildren from 40 schools of Kaunas region, Lithuania. Study participants underwent anthropometric measurements. Body mass index (BMI) was evaluated according to International Obesity Task Force (IOTF) criteria for children and adolescents. Children and adolescents and their parents filled in the questionnaires on parental sociodemographic characteristics, dietary habits, TV watching time, and family socioeconomic status. The prevalence of underweight, overweight, and obesity among boys and girls was 6.9 and 11.7 % (P < 0.05), 12.6 and 12.6 % (P > 0.05), and 4.9 and 3.4 % (P < 0.05), respectively. Obesity was significantly more prevalent in the 7-9 years old group (6.7 and 4.8 % in boys and girls, respectively, P < 0.05). Lower meals frequency and breakfast skipping were directly associated with overweight/obesity (P < 0.05); however, physical inactivity was not associated with higher BMI. Children's overweight/obesity was directly associated with lower paternal education and unemployment (OR 1.30, P = 0.013 and OR 1.56, P = 0.003, respectively). The prevalence of overweight and obesity among 7-17 years old Lithuanian children and adolescents was more prevalent in younger age, still being one of the lowest across the European countries. Meals frequency, breakfast skipping, paternal education and unemployment as well as a family history of arterial hypertension were found to be associated with children's and adolescents' overweight/obesity.

MUTYH-associated colorectal cancer and adenomatous polyposis.

PubMed

Yamaguchi, Satoru; Ogata, Hideo; Katsumata, Daisuke; Nakajima, Masanobu; Fujii, Takaaki; Tsutsumi, Soichi; Asao, Takayuki; Sasaki, Kinro; Kuwano, Hiroyuki; Kato, Hiroyuki

2014-04-01

MUTYH-associated polyposis (MAP) was first described in 2002. MUTYH is a component of a base excision repair system that protects the genomic information from oxidative damage. When the MUTYH gene product is impaired by bi-allelic germline mutation, it leads to the mutation of cancer-related genes, such as the APC and/or the KRAS genes, via G to T transversion. MAP is a hereditary colorectal cancer syndrome inherited in an autosomal-recessive fashion. The clinical features of MAP include the presence of 10-100 adenomatous polyps in the colon, and early onset of colorectal cancer. Ethnic and geographical differences in the pattern of the MUTYH gene mutations have been suggested. In Caucasian patients, c.536A>G (Y179C) and c.1187G>A (G396D) mutations are frequently detected. In the Asian population, Y179C and G396D are uncommon, whereas other variants are suggested to be the major causes of MAP. We herein review the literature on MUTYH-associated colorectal cancer and adenomatous polyposis.

Culture and the prevalence of hallucinations in schizophrenia.

PubMed

Bauer, Susanne M; Schanda, Hans; Karakula, Hanna; Olajossy-Hilkesberger, Luiza; Rudaleviciene, Palmira; Okribelashvili, Nino; Chaudhry, Haroon R; Idemudia, Sunday E; Gscheider, Sharon; Ritter, Kristina; Stompe, Thomas

2011-01-01

Besides demographic, clinical, familial, and biographical factors, culture and ethnicity may plausibly influence the manifestation of hallucinations. The purpose of this study was to investigate the influence of culture on the frequency of different kinds of hallucinations in schizophrenia. Patients with a clinical diagnosis of schizophrenia were diagnosed by means of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria. Seven independent samples were consecutively recruited in Austria, Lithuania, Poland, Georgia, Ghana, Nigeria, and Pakistan using identical inclusion/exclusion criteria and assessment procedures (N = 1080 patients total). The association of key demographic factors (sex and age), clinical factors (age at onset and duration of illness), and country of origin with hallucinations of different kinds was examined. The prevalence of various kinds of hallucinations was substantially different in the samples; however, the rank order of their occurrence was similar. Auditory hallucinations were relatively infrequent in Austria and Georgia and more prevalent in patients with an early age at onset of disease. Visual hallucinations were more frequently reported by the West African patients compared with subjects from the other 5 countries. Cenesthetic hallucinations were most prevalent in Ghana and in patients with a long duration of illness. We hypothesize that the prevalence of the different kinds of hallucinations in schizophrenia is the result of the interaction of a variety of factors like cultural patterns as well as clinical parameters. According to our study, culture seems to play a decisive role and should be taken into account to a greater extent in considerations concerning the pathogenesis of psychotic symptoms. Copyright © 2011 Elsevier Inc. All rights reserved.

Self-reported Ethnicity, Genetic Structure and the Impact of Population Stratification in a Multiethnic Study

PubMed Central

Wang, Hansong; Haiman, Christopher A.; Kolonel, Laurence N.; Henderson, Brian E.; Wilkens, Lynne R.; Le Marchand, Loïc; Stram, Daniel O.

2011-01-01

It is well-known that population substructure may lead to confounding in case-control association studies. Here, we examined genetic structure in a large racially and ethnically diverse sample consisting of 5 ethnic groups of the Multiethnic Cohort study (African Americans, Japanese Americans, Latinos, European Americans and Native Hawaiians) using 2,509 SNPs distributed across the genome. Principal component analysis on 6,213 study participants, 18 Native Americans and 11 HapMap III populations revealed 4 important principal components (PCs): the first two separated Asians, Europeans and Africans, and the third and fourth corresponded to Native American and Native Hawaiian (Polynesian) ancestry, respectively. Individual ethnic composition derived from self-reported parental information matched well to genetic ancestry for Japanese and European Americans. STRUCTURE-estimated individual ancestral proportions for African Americans and Latinos are consistent with previous reports. We quantified the East Asian (mean 27%), European (mean 27%) and Polynesian (mean 46%) ancestral proportions for the first time, to our knowledge, for Native Hawaiians. Simulations based on realistic settings of case-control studies nested in the Multiethnic Cohort found that the effect of population stratification was modest and readily corrected by adjusting for race/ethnicity or by adjusting for top PCs derived from all SNPs or from ancestry informative markers; the power of these approaches was similar when averaged across causal variants simulated based on allele frequencies of the 2,509 genotyped markers. The bias may be large in case-only analysis of gene by gene interactions but it can be corrected by top PCs derived from all SNPs. PMID:20499252

Trans-ethnic meta-analysis of white blood cell phenotypes

PubMed Central

Keller, Margaux F.; Reiner, Alexander P.; Okada, Yukinori; van Rooij, Frank J.A.; Johnson, Andrew D.; Chen, Ming-Huei; Smith, Albert V.; Morris, Andrew P.; Tanaka, Toshiko; Ferrucci, Luigi; Zonderman, Alan B.; Lettre, Guillaume; Harris, Tamara; Garcia, Melissa; Bandinelli, Stefania; Qayyum, Rehan; Yanek, Lisa R.; Becker, Diane M.; Becker, Lewis C.; Kooperberg, Charles; Keating, Brendan; Reis, Jared; Tang, Hua; Boerwinkle, Eric; Kamatani, Yoichiro; Matsuda, Koichi; Kamatani, Naoyuki; Nakamura, Yusuke; Kubo, Michiaki; Liu, Simin; Dehghan, Abbas; Felix, Janine F.; Hofman, Albert; Uitterlinden, André G.; van Duijn, Cornelia M.; Franco, Oscar H.; Longo, Dan L.; Singleton, Andrew B.; Psaty, Bruce M.; Evans, Michelle K.; Cupples, L. Adrienne; Rotter, Jerome I.; O'Donnell, Christopher J.; Takahashi, Atsushi; Wilson, James G.; Ganesh, Santhi K.; Nalls, Mike A.

2014-01-01

White blood cell (WBC) count is a common clinical measure used as a predictor of certain aspects of human health, including immunity and infection status. WBC count is also a complex trait that varies among individuals and ancestry groups. Differences in linkage disequilibrium structure and heterogeneity in allelic effects are expected to play a role in the associations observed between populations. Prior genome-wide association study (GWAS) meta-analyses have identified genomic loci associated with WBC and its subtypes, but much of the heritability of these phenotypes remains unexplained. Using GWAS summary statistics for over 50 000 individuals from three diverse populations (Japanese, African-American and European ancestry), a Bayesian model methodology was employed to account for heterogeneity between ancestry groups. This approach was used to perform a trans-ethnic meta-analysis of total WBC, neutrophil and monocyte counts. Ten previously known associations were replicated and six new loci were identified, including several regions harboring genes related to inflammation and immune cell function. Ninety-five percent credible interval regions were calculated to narrow the association signals and fine-map the putatively causal variants within loci. Finally, a conditional analysis was performed on the most significant SNPs identified by the trans-ethnic meta-analysis (MA), and nine secondary signals within loci previously associated with WBC or its subtypes were identified. This work illustrates the potential of trans-ethnic analysis and ascribes a critical role to multi-ethnic cohorts and consortia in exploring complex phenotypes with respect to variants that lie outside the European-biased GWAS pool. PMID:25096241

AFRICAN GENETIC DIVERSITY: Implications for Human Demographic History, Modern Human Origins, and Complex Disease Mapping

PubMed Central

Campbell, Michael C.; Tishkoff, Sarah A.

2010-01-01

Comparative studies of ethnically diverse human populations, particularly in Africa, are important for reconstructing human evolutionary history and for understanding the genetic basis of phenotypic adaptation and complex disease. African populations are characterized by greater levels of genetic diversity, extensive population substructure, and less linkage disequilibrium (LD) among loci compared to non-African populations. Africans also possess a number of genetic adaptations that have evolved in response to diverse climates and diets, as well as exposure to infectious disease. This review summarizes patterns and the evolutionary origins of genetic diversity present in African populations, as well as their implications for the mapping of complex traits, including disease susceptibility. PMID:18593304

On normality, ethnicity, and missing values in quantitative trait locus mapping

PubMed Central

Labbe, Aurélie; Wormald, Hanna

2005-01-01

Background This paper deals with the detection of significant linkage for quantitative traits using a variance components approach. Microsatellite markers were obtained for the Genetic Analysis Workshop 14 Collaborative Study on the Genetics of Alcoholism data. Ethnic heterogeneity, highly skewed quantitative measures, and a high rate of missing values are all present in this dataset and well known to impact upon linkage analysis. This makes it a good candidate for investigation. Results As expected, we observed a number of changes in LOD scores, especially for chromosomes 1, 7, and 18, along with the three factors studied. A dramatic example of such changes can be found in chromosome 7. Highly significant linkage to one of the quantitative traits became insignificant when a proper normalizing transformation of the trait was used and when analysis was carried out on an ethnically homogeneous subset of the original pedigrees. Conclusion In agreement with existing literature, transforming a trait to ensure normality using a Box-Cox transformation is highly recommended in order to avoid false-positive linkages. Furthermore, pedigrees should be sorted by ethnic groups and analyses should be carried out separately. Finally, one should be aware that the inclusion of covariates with a high rate of missing values reduces considerably the number of subjects included in the model. In such a case, the loss in power may be large. Imputation methods are then recommended. PMID:16451664

Pheromone traps and other methods in assessing pine beauty moth (Panolis flammea Schiff.)

Treesearch

Algimantas Ziogas

2003-01-01

The objective of this research was to evaluate different methodologies for quantifying pine beauty moth (Panolis flammea Schiff.) populations in pine stands of Southern part of Lithuania. Evaluations were conducted in selected pine stands by assessing the following: pupae (in the litter); larvae (falling from trees after chemical knock down); and...

Internationalisation as a Strategy to Improve the Quality of Higher Education in Small States: Stakeholder Perspectives in Lithuania

ERIC Educational Resources Information Center

Urbanovic, Jolanta; Wilkins, Stephen

2013-01-01

Assumptions have developed around the benefits of internationalisation; for example, that it promotes cultural integration and harmony, improves the quality of education and research, and improves country and institutional reputations internationally. A range of coercive, normative and mimetic influences have pushed most small states with mass or…

Leadership Style and Job Satisfaction in Higher Education Institutions

ERIC Educational Resources Information Center

Alonderiene, Raimonda; Majauskaite, Modesta

2016-01-01

Purpose: Although leadership is found to have impact on the followers' attitudes and performance there is a gap in leadership studies in HEIs, especially having Lithuania in mind. The purpose of this paper is to study the impact of leadership style on job satisfaction of faculty in higher education institutions (HEI). Design/methodology/approach:…

Pine beauty moth (Panolis flammea Schiff.) outbreak management: suppression versus natural enemies

Treesearch

Paulius Zolubas

2003-01-01

Pine beauty moth (Panolis flammea Schiff.) is one of the most serious defoliators that periodically threatens Scotch pine forests on poor sandy soils in Lithuania. Population increase of this pest began in 1999. Because a maximum of only 15% defoliation was predicted in particular areas, no additional funding was required for suppressing the...

Assessment and Recognition of Non-Formal and Informal Learning: A Lithuanian Case of Novice Consultants' Experience

ERIC Educational Resources Information Center

Burkšaitiene, Nijole

2015-01-01

This article reports the results of the investigation into institutional support provided to adults by 12 novice consultants on assessment and recognition of their non-formal and informal learning in four institutions of higher education (HEIs) in Lithuania. Using the general systems perspective and perception theory, novice consultants'…

SCREENING BIOAVAILABLE HYDROPHOBIC TOXICANTS IN SURFACE WATERS WITH SEMIPERMEABLE MEMBRANE DEVICES: ROLE OF INHERENT OLEIC ACID IN TOXICITY EVALUATIONS

EPA Science Inventory

Semipermeable membrane devices (SPMDs) were deployed for 4 weeks in two rivers in Lithuania, The SPMD dialysates were tested in the Microtox assay and, surprisingly, the sample from the relatively clean (U) over bar la River exhibited three times more toxicity than the sample fro...

Cross National Study on Pre-Service Elementary and Science Teachers' Opinions on Science Teaching

ERIC Educational Resources Information Center

Šorgo, Andrej; Pipenbaher, Nataša; Šašic, Slavica Šimic; Prokop, Pavol; Kubiatko, Milan; Golob, Nika; Erdogan, Mehmet; Tomažic, Iztok; Bilek, Martin; Fancovicova, Jana; Lamanauskas, Vincentas; Usak, Muhammet

2015-01-01

Cross national study on opinions on science teaching was revealed on a sample of 1799 (596 males, 1203 females) pre-service elementary and science teachers' enrolled in various departments at selected universities in Croatia, Czech Republic, Lithuania, Slovakia, Slovenia and Turkey. Three factors explaining 43.4% of variance were extracted from a…

A Sociolinguistic Comparison between Quebec's Charter of the French Language and the 1989 Language Laws of Five Soviet Republics.

ERIC Educational Resources Information Center

Maurais, Jacques

1991-01-01

Compares the language laws of five Soviet Republics (Estonia, Latvia, Lithuania, Moldavia, and Kazakhstan) with Quebec's Charter of the French Language along the following lines: proclamation of an official language; the common language in question; language of communication with customers and citizens; language of education; and linguistic…

Transnational Analysis of Vocational Education and Training in the Countries of Central and Eastern Europe. Report.

ERIC Educational Resources Information Center

European Training Foundation, Turin (Italy).

Vocational education and training (VET) in 10 Central and Eastern European countries--Bulgaria, Czech Republic, Estonia, Hungary, Latvia, Lithuania, Poland, Romania, Slovak Republic, and Slovenia--was examined. The analysis focused on the following issues: socioeconomic context of VET reforms; VET at the start of reforms; the European Union Phare…

Access to nature in lithuania: Limits, perceptions and design issues

Treesearch

Aida Macerinskiene

2015-01-01

One of the factors in local tourism could be nature tourism promotion for disabled people in protected areas. This social group is more sensitive to long-distance travel; therefore, it is likely that local tourism is especially attractive. The disabled population may possibly have more free time, which also makes local travel particularly attractive. The main focus...

Stakeholders' Cooperation in the Study Programme Quality Assurance: Theory and Practice in Lithuania

ERIC Educational Resources Information Center

Pileicikiene, Nora

2011-01-01

The cooperation of various stakeholders' groups is a prerequisite to develop and realise high-quality study programmes, i.e. during studies to develop skills that are relevant to the labour market and social life. In order to achieve effective stakeholders' cooperation, it is necessary to identify stakeholder's groups relevant to a study programme…

Phytoplasma infection in prized linden cultivar Tilia platyphyllos “Laciniata”: Is “Laciniata” a valid cultivar?

USDA-ARS?s Scientific Manuscript database

Linden (Tilia platyphyllos ‘Laciniata’) trees growing in Kaunas Botanical Garden and in the parks of Verkiu (Vilnius) and Belvederis estates in Lithuania exhibited laciniated, deformed leaves and yellowing of veins. These trees had been planted in the parks, for the beauty of their “cut-out-elongate...

Trade Remedies: A Primer

DTIC Science & Technology

2007-05-01

Turkmenistan Turkey Trinidad Tajikistan Pakistan Philippines Malaysia Lithuania Latvia Estonia Ecuador Czechoslovakia Bangladesh Poland Norway Moldova Iran...while continuing domestic production of more high-end items. Many furniture retailers reportedly became furious with furniture industry petitioners...because they feared that the higher prices caused by possible AD duties would depress sales and result in the layoffs of retail employees. Furniture

Teachers' Workplace Learning within Informal Contexts of School Cultures in the United States and Lithuania

ERIC Educational Resources Information Center

Jurasaite-Harbison, Elena

2009-01-01

Purpose: The purpose of this paper is to explore informal contexts of teachers' workplace professional learning and inform educational researchers, teacher educators, administrators and teachers about ways in which teachers learn to improve their practice. By questioning how teachers learn on-the-job to be better teachers and how school cultures…

Re-Learning Higher Education in the Age of Convergence: Example of Lithuania

ERIC Educational Resources Information Center

Ulvydiene, Loreta

2012-01-01

Since May of 1999, 46 European countries have been engaged in reconstructing their higher education systems to bring about a greater degree of "convergence," i.e. a move toward common reference points and operating procedures to create a European Higher Education Area. Education has always played an important role in the development of…

MuseumScouts: Exploring How Schools, Museums and Interactive Technologies Can Work Together to Support Learning

ERIC Educational Resources Information Center

Wishart, Jocelyn; Triggs, Pat

2010-01-01

In this paper we report on the successes and challenges of a creative project involving museums, schools and interactive technologies. The MuseumScouts project is EU Comenius 2.1 funded and involves teachers, teacher educators, museum staff, students and researchers from five European countries: Germany (Berlin and Munich), Lithuania (Vilnius),…

European Enlargement and the Integration of the Western Balkans

DTIC Science & Technology

2003-06-01

Balkans 6 . AUTHOR(S) Leonard Demi 5. FUNDING NUMBERS 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School...7th centuries, had the greatest effect on the subsequent ethnic composition of the area. 6 Jelavich, B., History of the Balkans: 20th Century, v...republic. The people were disappointed and demonstrated [Lee, M., “Kosovo between Yugoslavia and Albania,” New Left Review, 6 map of the Balkans

Assessing the Causality between Blood Pressure and Retinal Vascular Caliber through Mendelian Randomisation

NASA Astrophysics Data System (ADS)

Li, Ling-Jun; Liao, Jiemin; Cheung, Carol Yim-Lui; Ikram, M. Kamran; Shyong, Tai E.; Wong, Tien-Yin; Cheng, Ching-Yu

2016-02-01

We aimed to determine the association between blood pressure (BP) and retinal vascular caliber changes that were free from confounders and reverse causation by using Mendelian randomisation. A total of 6528 participants from a multi-ethnic cohort (Chinese, Malays, and Indians) in Singapore were included in this study. Retinal arteriolar and venular caliber was measured by a semi-automated computer program. Genotyping was done using Illumina 610-quad chips. Meta-analysis of association between BP, and retinal arteriolar and venular caliber across three ethnic groups was performed both in conventional linear regression and Mendelian randomisation framework with a genetic risk score of BP as an instrumental variable. In multiple linear regression models, each 10 mm Hg increase in systolic BP, diastolic BP, and mean arterial BP (MAP) was associated with significant decreases in retinal arteriolar caliber of a 1.4, 3.0, and 2.6 μm, and significant decreases in retinal venular caliber of a 0.6, 0.7, and 0.9 μm, respectively. In a Mendelian randomisation model, only associations between DBP and MAP and retinal arteriolar narrowing remained yet its significance was greatly reduced. Our data showed weak evidence of a causal relationship between elevated BP and retinal arteriolar narrowing.

From Redlining to Benevolent Societies: The Emancipatory Power of Spatial Thinking

PubMed Central

MITCHELL, KATHARYNE; ELWOOD, SARAH

2015-01-01

This study highlights the power of place, and reconceptualizes geography education as integral to the larger project of teaching for democratic citizenship. Using an interactive web platform, the researchers asked 29 seventh grade girls to research and map significant cultural and historical places associated with an ethnic group, or women, in the city of Seattle. The students worked in teams and commented frequently on each other’s contributions. Adopting a participatory action research method, the researchers studied the multiple ways in which a greater understanding of spatial production, such as processes of exclusion and inclusion, or mapping and counter-mapping, can give students the knowledge and will to challenge prevailing norms about the “naturalness” of a segregated urban landscape, or the inequitable allocation of resources. This approach follows recent feminist, anti-racist, and internationalist articulations of citizenship education, which advocate a social justice or emancipatory component to teaching and learning. PMID:25635148

Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A

PubMed Central

Wang, Hansong; Burnett, Terrilea; Kono, Suminori; Haiman, Christopher A.; Iwasaki, Motoki; Wilkens, Lynne R.; Loo, Lenora W.M.; Berg, David Van Den; Kolonel, Laurence N.; Henderson, Brian E.; Keku, Temitope O.; Sandler, Robert S.; Signorello, Lisa B.; Blot, William J.; Newcomb, Polly A.; Pande, Mala; Amos, Christopher I.; West, Dee W.; Bézieau, Stéphane; Berndt, Sonja I.; Zanke, Brent W.; Hsu, Li; Lindor, Noralane M.; Haile, Robert W.; Hopper, John L.; Jenkins, Mark A.; Gallinger, Steven; Casey, Graham; Stenzel, Stephanie L.; Schumacher, Fredrick R.; Peters, Ulrike; Gruber, Stephen B.; Tsugane, Shoichiro; Stram, Daniel O.; Marchand, Loïc Le

2014-01-01

The genetic basis of sporadic colorectal cancer (CRC) is not well explained by known risk polymorphisms. Here we perform a meta-analysis of two genome-wide association studies in 2,627 cases and 3,797 controls of Japanese ancestry and 1,894 cases and 4,703 controls of African ancestry, to identify genetic variants that contribute to CRC susceptibility. We replicate genome-wide statistically significant associations (P < 5×10−8) in 16,823 cases and 18,211 controls of European ancestry. This study reveals a new pan-ethnic CRC risk locus at 10q25 (rs12241008, intronic to VTI1A; P=1.4×10−9), providing additional insight into the etiology of CRC and highlighting the value of association mapping in diverse populations. PMID:25105248

A 1000 Arab genome project to study the Emirati population.

PubMed

Al-Ali, Mariam; Osman, Wael; Tay, Guan K; AlSafar, Habiba S

2018-04-01

Discoveries from the human genome, HapMap, and 1000 genome projects have collectively contributed toward the creation of a catalog of human genetic variations that has improved our understanding of human diversity. Despite the collegial nature of many of these genome study consortiums, which has led to the cataloging of genetic variations of different ethnic groups from around the world, genome data on the Arab population remains overwhelmingly underrepresented. The National Arab Genome project in the United Arab Emirates (UAE) aims to address this deficiency by using Next Generation Sequencing (NGS) technology to provide data to improve our understanding of the Arab genome and catalog variants that are unique to the Arab population of the UAE. The project was conceived to shed light on the similarities and differences between the Arab genome and those of the other ethnic groups.

Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A.

PubMed

Wang, Hansong; Burnett, Terrilea; Kono, Suminori; Haiman, Christopher A; Iwasaki, Motoki; Wilkens, Lynne R; Loo, Lenora W M; Van Den Berg, David; Kolonel, Laurence N; Henderson, Brian E; Keku, Temitope O; Sandler, Robert S; Signorello, Lisa B; Blot, William J; Newcomb, Polly A; Pande, Mala; Amos, Christopher I; West, Dee W; Bézieau, Stéphane; Berndt, Sonja I; Zanke, Brent W; Hsu, Li; Lindor, Noralane M; Haile, Robert W; Hopper, John L; Jenkins, Mark A; Gallinger, Steven; Casey, Graham; Stenzel, Stephanie L; Schumacher, Fredrick R; Peters, Ulrike; Gruber, Stephen B; Tsugane, Shoichiro; Stram, Daniel O; Le Marchand, Loïc

2014-08-08

The genetic basis of sporadic colorectal cancer (CRC) is not well explained by known risk polymorphisms. Here we perform a meta-analysis of two genome-wide association studies in 2,627 cases and 3,797 controls of Japanese ancestry and 1,894 cases and 4,703 controls of African ancestry, to identify genetic variants that contribute to CRC susceptibility. We replicate genome-wide statistically significant associations (P<5 × 10(-8)) in 16,823 cases and 18,211 controls of European ancestry. This study reveals a new pan-ethnic CRC risk locus at 10q25 (rs12241008, intronic to VTI1A; P=1.4 × 10(-9)), providing additional insight into the aetiology of CRC and highlighting the value of association mapping in diverse populations.

A hot spot for systemic lupus erythematosus, but not for psoriatic arthritis, identified by spatial analysis suggests an interaction between ethnicity and place of residence.

PubMed

Al-Maini, Mustafa; Jeyalingam, Thurarshen; Brown, Patrick; Lee, Jennifer J Y; Li, Lennon; Su, Jiandong; Gladman, Dafna D; Fortin, Paul R

2013-06-01

To describe the spatial distribution of incident cases of systemic lupus erythematosus (SLE) using geographic information systems (GIS). Spatial analyses were carried out on 890 SLE patients and 541 psoriatic arthritis (PsA) patients (controls). Age- and sex-adjusted rates for SLE/PsA for each census tract were calculated using denominator population values from the Canadian census. Spatial variations in relative risk were estimated by modeling risk as the product of a time effect, an age effect, and a spatially autocorrelated risk surface to identify hot spots. Patients within the detected hot spot were compared to those outside the hot spot to identify explanatory factors. SLE patients were predominantly female (87.75%) and the incidence rate was highest among those 15-19 years of age (2.4 cases/100,000 person-years). In an SLE hot spot containing 59 patients, 100% of the patients were female and 49.1% (n = 29) were Caucasian, while outside of the hot spot, 86.9% (n = 722) of the patients were female and 68.4% (n = 568) were Caucasian. The proportion of cases of Chinese ethnicity was significantly greater within the hot spot. An interaction was found between Chinese ethnicity and residence within the hot spot, with the risk of SLE to the Chinese population found to be twice the risk to the non-Chinese population. GIS was used to map SLE cases and a hot spot was identified after adjustment for age and sex. Ethnicity by itself did not confer an increased risk of SLE, but the interaction of ethnicity with location of residence significantly increased the risk of SLE. Copyright © 2013 by the American College of Rheumatology.

Nation and Language: Modern Aspects of Socio-Linguistic Development. Proceedings of the 4th International Conference (Lithuania, October 21-22, 2010)

ERIC Educational Resources Information Center

Online Submission, 2010

2010-01-01

The 4th international conference "Nation and Language: Modern Aspects of Socio-Linguistic Development" continues an eight-year old tradition. The conference is organized by Kaunas University of Technology Panevezys Institute and aims to bring scientists and researchers together for a general scientific discussion on new trends in…

Institutional Assessment of Research and Studies: Inevitable Feature of a Modern State or One More Bureaucratic Whim in Lithuania?

ERIC Educational Resources Information Center

Dienys, Vincentas; Pukelis, Kestutis; Ziliukas, Pranas

2005-01-01

A number of small countries face similar problems while organising external assessment of higher education institutions: how to select proper experts, how to prepare them and maintain? How to avoid bias or interest conflict between experts who evaluate the institution and the institution being evaluated? How to reduce the financial costs of…

The Bologna Process and Its Impact on Higher Education at Russia's Margins: The Case of Kaliningrad

ERIC Educational Resources Information Center

Ganzle, Stefan; Meister, Stefan; King, Conrad

2009-01-01

Embracing the Russian Federation since 2003, the Bologna process is no longer exclusively confined to western European countries. As early as 1999, Vladimir Putin declared the Russian exclave of Kaliningrad, wedged between Lithuania and Poland, as a potential pilot region for intensified cooperation between Russia and the EU on a number of policy…

Schooling in the Kovno Ghetto: Cultural Reproduction as a Form of Defiance

ERIC Educational Resources Information Center

Slaten Frasier, Amanda Marie

2015-01-01

When Soviet forces entered the Kovno Ghetto (Lithuania) on 1 August 1944 they found a scene of mass destruction. What happened at Kovno was a reflection of the extent of the Final Solution, where the goal was to extinguish not only the Jews, but their entire culture. While the Final Solution was instituted throughout Europe, this paper will focus…

Attitudes to Agricultural Policy and Farming Futures in the Context of the 2003 CAP Reform: A Comparison of Farmers in Selected Established and New Member States

ERIC Educational Resources Information Center

Gorton, Matthew; Douarin, Elodie; Davidova, Sophia; Latruffe, Laure

2008-01-01

Farmers' attitudes, to agricultural production, diversification and policy support, and behavioural intentions in five Member States of the EU (France, Lithuania, Slovakia, Sweden, England) are analysed comparatively. Groups of farmers with similarly held attitudes are identified using cluster analysis to investigate whether differences in…

Environmental Issues in the Media--Students' Perceptions in the Three Nordic-Baltic Countries

ERIC Educational Resources Information Center

Keinonen, Tuula; Yli-Panula, Eija; Svens, Maria; Vilkonis, Rytis; Persson, Christel; Palmberg, Irmeli

2014-01-01

The media, as a source of information, is supposed to have a significant role in effecting people's environmental knowledge and attitudes. The purpose of this study was to find students' perceptions of environmental issues as presented in the media and how students in Finland, Lithuania and Sweden used these media sources in the matters related to…

Cross-Cultural Comparisons of Child-Reported Emotional and Physical Abuse: Rates, Risk Factors and Psychosocial Symptoms

ERIC Educational Resources Information Center

Sebre, Sandra; Sprugevica, Ieva; Novotni, Antoni; Bonevski, Dimitar; Pakalniskiene, Vilmante; Popescu, Daniela; Turchina, Tatiana; Friedrich, William; Lewis, Owen

2004-01-01

Objectives: This study was designed to assess the incidence of child emotional and physical abuse, associated risk factors and psychosocial symptoms in a cross-cultural comparison between post-communist bloc countries. Method: One-thousand one-hundred forty-five children ages 10-14 from Latvia (N=297), Lithuania (N=300), Macedonia (N=302), and…

Quadrennial Defense Review Report

DTIC Science & Technology

2010-02-01

medicine , and computer network operations. While we continue to employ a mix of programs and incentives to recruit quality personnel, we are also...Lithuania* Singapore Australia Finland Luxembourg* Slovakia* Austria France* Macedonia Slovenia* Azerbaijan Georgia Montenegro Spain* Belgium...20,000 positions by 2015. We will continue to significantly enhance Secretary of Defense Robert M. Gates meets with plant workers during a tour of an

Females of the genus Podmosta (Plecoptera: Nemouridae): comparison of terminalia and a new female record in Baltic Amber.

PubMed

Chen, Zhi-Teng

2018-04-10

Based on a specimen preserved in Baltic amber from Lithuania, a new fossil female of the nemourid genus Podmosta Ricker, 1952 is described, illustrated and compared to other described species of the genus. The new female specimen is distinguished from other Podmosta females by the "rabbit-shaped" sclerite on sternum 8.

Ethical and Legal Observations on Contract Cheating Services as an Agreement

ERIC Educational Resources Information Center

Tauginiene, Loreta; Jurkevicius, Vaidas

2017-01-01

In this paper we cast light on one form of dishonest behaviour in academia--contract cheating services. We examine how an agreement between a student and a contract cheating services provider is viewed from ethical and legal perspectives. For this purpose we carried out an analysis of contract cheating services as an agreement which, in Lithuania,…

The Economic Consciousness and Value Orientations of Graduates of the Higher Educational Institutions of Latgalia [Latvia

ERIC Educational Resources Information Center

Voronov, Viktor Vasil'evich

2010-01-01

This article is devoted to an analysis of the economic consciousness and current orientations of the graduates of higher educational institutions of the Latgalia region of Latvia, which shares borders with Pskov oblast in Russia and with Belarus and Lithuania. Latgalia, part of the Pskov and Vitebsk gubernias of the Russian state for about a…

Publishers' Responses to the E-Book Phenomenon: Survey Results from Three "Small Language" Markets

ERIC Educational Resources Information Center

Wilson, T. D.; Maceviciute, Elena

2016-01-01

Introduction: This paper reports on a study of publishers' attitudes towards e-books in the context of the global situation of e-book publishing. Comparative data are drawn from a replication of a survey carried out in Sweden, in Lithuania and in Croatia. Method: A self-completed questionnaire survey was undertaken, offering respondents the choice…

Use of GeoGebra in Primary Math Education in Lithuania: An Exploratory Study from Teachers' Perspective

ERIC Educational Resources Information Center

Žilinskiene, Inga; Demirbilek, Muhammet

2015-01-01

With the advance of information and communications technologies, new teaching tools are becoming more pervasive. These tools can be utilized in a variety of ways to improve and enhance math teaching. Considering the integration of technology in teaching mathematics, it is clear that the replacement of board and chalk with digital presentation…

Genetic Variation among African Swine Fever Genotype II Viruses, Eastern and Central Europe

PubMed Central

Fernández-Pinero, Jovita; Pelayo, Virginia; Gazaev, Ismail; Markowska-Daniel, Iwona; Pridotkas, Gediminas; Nieto, Raquel; Fernández-Pacheco, Paloma; Bokhan, Svetlana; Nevolko, Oleg; Drozhzhe, Zhanna; Pérez, Covadonga; Soler, Alejandro; Kolvasov, Denis; Arias, Marisa

2014-01-01

African swine fever virus (ASFV) was first reported in eastern Europe/Eurasia in 2007. Continued spread of ASFV has placed central European countries at risk, and in 2014, ASFV was detected in Lithuania and Poland. Sequencing showed the isolates are identical to a 2013 ASFV from Belarus but differ from ASFV isolated in Georgia in 2007. PMID:25148518

Cumulative Small Effect Genetic Markers and the Risk of Colorectal Cancer in Poland, Estonia, Lithuania, and Latvia

PubMed Central

Serrano-Fernandez, Pablo; Dymerska, Dagmara; Kurzawski, Grzegorz; Derkacz, Róża; Sobieszczańska, Tatiana; Banaszkiewicz, Zbigniew; Roomere, Hanno; Oitmaa, Eneli; Metspalu, Andres; Janavičius, Ramūnas; Elsakov, Pavel; Razumas, Mindaugas; Petrulis, Kestutis; Irmejs, Arvīds; Miklaševičs, Edvīns; Scott, Rodney J.; Lubiński, Jan

2015-01-01

The continued identification of new low-penetrance genetic variants for colorectal cancer (CRC) raises the question of their potential cumulative effect among compound carriers. We focused on 6 SNPs (rs380284, rs4464148, rs4779584, rs4939827, rs6983267, and rs10795668), already described as risk markers, and tested their possible independent and combined contribution to CRC predisposition. Material and Methods. DNA was collected and genotyped from 2330 unselected consecutive CRC cases and controls from Estonia (166 cases and controls), Latvia (81 cases and controls), Lithuania (123 cases and controls), and Poland (795 cases and controls). Results. Beyond individual effects, the analysis revealed statistically significant linear cumulative effects for these 6 markers for all samples except of the Latvian one (corrected P value = 0.018 for the Estonian, corrected P value = 0.0034 for the Lithuanian, and corrected P value = 0.0076 for the Polish sample). Conclusions. The significant linear cumulative effects demonstrated here support the idea of using sets of low-risk markers for delimiting new groups with high-risk of CRC in clinical practice that are not carriers of the usual CRC high-risk markers. PMID:26101521

Cumulative Small Effect Genetic Markers and the Risk of Colorectal Cancer in Poland, Estonia, Lithuania, and Latvia.

PubMed

Serrano-Fernandez, Pablo; Dymerska, Dagmara; Kurzawski, Grzegorz; Derkacz, Róża; Sobieszczańska, Tatiana; Banaszkiewicz, Zbigniew; Roomere, Hanno; Oitmaa, Eneli; Metspalu, Andres; Janavičius, Ramūnas; Elsakov, Pavel; Razumas, Mindaugas; Petrulis, Kestutis; Irmejs, Arvīds; Miklaševičs, Edvīns; Scott, Rodney J; Lubiński, Jan

2015-01-01

The continued identification of new low-penetrance genetic variants for colorectal cancer (CRC) raises the question of their potential cumulative effect among compound carriers. We focused on 6 SNPs (rs380284, rs4464148, rs4779584, rs4939827, rs6983267, and rs10795668), already described as risk markers, and tested their possible independent and combined contribution to CRC predisposition. Material and Methods. DNA was collected and genotyped from 2330 unselected consecutive CRC cases and controls from Estonia (166 cases and controls), Latvia (81 cases and controls), Lithuania (123 cases and controls), and Poland (795 cases and controls). Results. Beyond individual effects, the analysis revealed statistically significant linear cumulative effects for these 6 markers for all samples except of the Latvian one (corrected P value = 0.018 for the Estonian, corrected P value = 0.0034 for the Lithuanian, and corrected P value = 0.0076 for the Polish sample). Conclusions. The significant linear cumulative effects demonstrated here support the idea of using sets of low-risk markers for delimiting new groups with high-risk of CRC in clinical practice that are not carriers of the usual CRC high-risk markers.

Changes in precipitation regime in the Baltic countries in 1966-2015

NASA Astrophysics Data System (ADS)

Jaagus, Jaak; Briede, Agrita; Rimkus, Egidijus; Sepp, Mait

2018-01-01

The aim of the study was to analyse trends and regime shifts in time series of monthly, seasonal and annual precipitation in the eastern Baltic countries (Lithuania, Latvia, Estonia) during 1966-2015. Data from 54 stations with nearly homogeneous series were used. The Mann-Kendall test was used for trend analysis and the Rodionov test for the analysis of regime shifts. Rather few statistically significant trends ( p < 0.05) and regime shifts were determined. The highest increase (by approximately 10 mm per decade) was observed in winter precipitation when a significant trend was found at the large majority of stations. For monthly precipitation, increasing trends were detected at many stations in January, February and June. Weak negative trends revealed at few stations in April and September. Annual precipitation has generally increased, but the trend is mostly insignificant. The analysis of regime shifts revealed some significant abrupt changes, the most important of which were upward shifts in winter, in January and February precipitation at many stations since 1990 or in some other years (1989, 1995). A return shift in the time series of February precipitation occurred since 2003. The most significant increase in precipitation was determined in Latvia and the weakest increase in Lithuania.

Metamorphism and magmatism in the western East European Craton: implications for 1.84 to 1.45 Ga evolution in Lithuania

NASA Astrophysics Data System (ADS)

Skridlaite, Grazina; Baginski, Boguslaw; Bogdanova, Svetlana; Whitehouse, Martin

2010-05-01

The western East European Craton (EEC) was formed by the accretion of distinct terrains at c. 1.8 Ga. Some boundaries between particular terrains and their continuation across the Baltic Sea from Lithuania to Sweden have to be justified. Recently obtained numerous U-Pb zircon ages from the Siupariai 3 (Sp3), Palukne 1 (Pl1) charnockites, Rukai 1 (Rk1), Geluva 99 (Gl99) granitoids, Bliudziai 150 (Bl150), Lauksargiai (Lk2, 5) and Pociai 3(Pc3) granulites determined using a Cameca ims1270 instrument of the Nordic high-resolution ion-microprobe facility (NORDSIM), as well as monazites of the Sp3, Pl1, Vydmantai 1 (Vd1) charnockites, Lk2, 5, Bl150 granulites dated by Cameca SX-100 electron microprobe (EPMA dating) at University of Warsaw allowed to reconstruct terrain boundaries from north to south in western Lithuania and a sequence of crust-forming events. In the north, the slightly deformed, coarse-grained Sp3, Pl1 and Vd1 (Claesson et al., 2001) charnockitoids crystallized in the time span of c. 1.84-1.81 Ga. The magmatic zircons contain a few c. 2.4-2.0 Ga inherited cores. The rocks were deformed and thermally reworked immediately after their crystallization as indicated by c. 1.79-1.74 Ga zircons and c. 1.85-1.76 Ga high-Y monazites, but the major metamorphism they underwent not earlier than c. 1.70 Ga. Thick zircon rims and rounded sector-zoned metamorphic zircons of c. 1.70 Ga likely grew together with peak garnet at 800o C, 7 kbar (Sp3) or 760o C and 6.5 kbar (Pl1). Numerous 1.62-1.56 Ga monazites recorded decompression to 2 kbar and cooling to 500o C in Sp3, mostly cooling to 450o C (at 4 kbar) in Pl1, and isothermal decompression from 650o C at 7 kbar to 500o C at 3 kbar in Vd1. In the south, the Bl150, Lk2, 5 and Pc 3 metasedimentary granulites containing a wide age range (3.0 to 1.85 Ga) of detrital zircons were deposited not earlier than 1.89 Ga. An incipient metamorphism started with the growth of relatively high-Y monazite (Y>3%) at 1.84-1.83 Ga, however a peak of 850o C at 9-10 kbar was likely achieved c. 1.80 Ga ago as indicated by metamorphic zircon (Lk2), and confirmed with 1.81-1.79 Ga monazite. Two isobaric cooling steps after the peak may be attributed to the two episodes of monazite growth at 1.72-1.70 and 1.63-1.62 Ga (Bl150) or at 1.70-1.64 Ga (Lk2, 5). The Rusne 1 tonalites intruded the metasedimentary granulites at c. 1.81 Ga (Claesson et al., 2001). To sum up, the 1.84-1.81 charnockitic magmatism in northwestern Lithuania can be correlated with TIB 0 magmatism in south-central Sweden and may be attributed to an active continental margin as well. This indicates a terrane boundary in west Lithuania earlier not recognized. The c. 1.81 Ga granitic magmatism and c. 1.81 -1.76 Ga metamorphism are related to major accretion of the western EEC when a volcanic island arc, which is identified in NE Poland, southern and central Lithuania in the present south (Wiszniewska et al., 2005), possibly collided with the continental margin in the north. The 1.70-1.60 Ga metamorphic events can reflect a distal influence of the 1.7-1.6 Ga Gothian orogeny in SW Fennoscandia (e.g. Ahall and Connelly, 2008). The 1.55-1.45 Ga AMCG magmatism, c. 1.56 Ga metamorphism and deformation of charnockites can be manifestations of the Danopolonian orogeny, particularly prominent around the South Baltic Sea. This is a contribution to the project "The Precambrian structure of Baltica as a control of its recent environment and evolution" of the Visby Programme (the Swedish Institute), Lithuanian Science and Study Foundation and SYNTHESYS project SE-TAF-1535. References Ahall, K.I. and Connelly, J.N., 2008. Precambrian Research, 161(3-4): 452-474. Claesson, S., et al., Tectonophysics, 339 (1-2), 1-18. Wiszniewska et al., 2005, 104-108, Scientific Communications, Warsaw.

Segregation and Neighborhood Change in Northern Cities: New Historical GIS Data from 1900-1930.

PubMed

Shertzer, Allison; Walsh, Randall P; Logan, John R

2016-01-01

Most quantitative research on segregation and neighborhood change in American cities prior to 1940 has utilized data published by the Census Bureau at the ward level. The transcription of census manuscripts has made it possible to aggregate individual records to a finer level, the enumeration district (ED). Advances in Geographic Information Systems (GIS) have facilitated mapping these data, opening new possibilities for historical GIS research. We report here the creation of a mapped public use data set for EDs in ten northern cities for each decade from 1900 to 1930. We illustrate a range of research topics that can now be pursued: recruitment into ethnic neighborhoods, the effects of comprehensive zoning on neighborhood change, and white flight from black neighbors.

Mapping Cultural Ecosystem Services in Vilnius using Hot-Spot Analysis.

NASA Astrophysics Data System (ADS)

Pereira, Paulo; Depellegrin, Daniel; Egarter-Vigl, Lukas; Oliva, Marc; Misiune, Ieva; Keesstra, Saskia; Estebaranz, Ferran; Cerda, Artemi

2017-04-01

Cultural services in urban areas are very important to promote tourism activities and develop the economy. These activities are fundamental for the sustainability of the urban areas since can represent an important monetary source. However, one of the major threats to the sustainability of cultural services is the high amount of visitants that can lead to a degradation of the services provided (Depellegrin et al., 2016). Mapping the potential of cultural ecosystems services is fundamental to assess the capacity that the territory have to provide it. Previous works used land use classification to identify the ecosystem services potential, and revealed to be a good methodology to attribute to each type of land use a specific capacity (Burkhard et al., 2008). The objective of this work is to map the cultural services in Vilnius area using a hot-spot analysis. Ecosystem services potential was assessed using the matrix developed by Burkhard et al. (2009), which ranks ES capacity from 0= no capacity to 5=very high relevant capacity to a different land use type. The results showed that with the exception of Cultural Heritage ecosystem services that had a random pattern (Z-score=0.62, p<0.530), all the others had clustered pattern: Recreation and Tourism (Z-score=4.02, p<0.001), Landscape Aesthetics (Z-score=4.44, p<0.001), Knowledge Systems (Z-score=4.15, p<0.001), Religious and Spiritual (Z-score=3.80, p<0.001) and Natural Heritage (Z-score=5.64, p<0.001). The incremental Moran's I result showed that Recreation and Tourism ecosystem services had the maximum spatial correlation at the distance of 5125.12 m, Landscape Aesthetics at 3495.70 m, Knowledge Systems at 5218.66 m, Religious and Spiritual at 3495.70 m, Cultural Heritage at 6746.17 m and Natural Heritage at 6205.82 m. This showed that the cultural services studied have a different spatial correlation. References Burkhard B, Kroll F, Müller F, Windhorst W. 2009. Landscapes' capacities to provide ecosystem services- a concept for land-cover based assessments. Landscape Online. 15, 1-22. Depellegrin, D.A., Pereira, P., Misiune, I., Egarter-Vigl, L. Mapping Ecosystem Services potential in Lithuania. International Journal of Sustainable Development and World Ecology, 23, 441-455.

Comprehensive epitope mapping of the Epstein-Barr virus latent membrane protein-2 in normal, non tumor-bearing individuals.

PubMed

Provenzano, Maurizio; Selleri, Silvia; Jin, Ping; Wang, Ena; Werden, Rosemary; Slezak, Stephanie; Adams, Sharon D; Panelli, Monica C; Leitman, Susan F; Stroncek, David F; Marincola, Francesco M

2007-07-01

Latent membrane protein (LMP)-2 is one of the Epstein-Barr virus (EBV)-encoded proteins consistently expressed by nasopharyngeal carcinoma (NPC). EBV-transformed lymphoblastoid cell lines (LCL) have been used in patients with NPC to induce LMP-2-recognizing T cell lines which have been in turn utilized for protein-wide mapping of T cell epitopes. However, comprehensive mapping of naturally recognized LMP-2 epitopes in non tumor-bearing individuals has not been reported. Here, we applied a low sensitivity epitope-defining technique for the identification of LMP-2 CTL responses detectable ex vivo in EBV-experienced individuals. This screening tool has been previously validated by analyzing memory CTL responses to Flu, cytomegalovirus (CMV), and the melanoma associated antigen gp100/Mel17. Peripheral blood monocytes (PBMC) from ten Caucasian and ten Chinese individuals were stimulated ex vivo with pools of nonamer (9-mer) peptides overlapping in a stepwise fashion each single amino acid of the LMP-2 sequence. No obvious differences were observed between the immune response of the two ethnic groups save for those related to the divergence in the ethnic prevalence of HLA haplotypes. Several novel and known LMP-2 epitopes were identified. Reactivity toward at least one LMP-2 epitope was detected in 18 of the 20 donors but no prevalent human leukocyte antigen (HLA)/epitope combination was observed confirming that LMP-2 reactivity in the context of common HLA alleles is more pleiotropic than that of FLU and CMV. We believe that the usefulness of these epitopes occurring naturally in non-cancer bearing patients as reagents for the immunization of patients with early or advanced stage NPC deserves further evaluation.

Intrahepatic Cholestasis of Pregnancy (ICP) in U.S. Latinas and Chileans: Clinical features, Ancestry Analysis, and Admixture Mapping.

PubMed

Bull, Laura N; Hu, Donglei; Shah, Sohela; Temple, Luisa; Silva, Karla; Huntsman, Scott; Melgar, Jennifer; Geiser, Mary T; Sanford, Ukina; Ortiz, Juan A; Lee, Richard H; Kusanovic, Juan P; Ziv, Elad; Vargas, Juan E

2015-01-01

In the Americas, women with Indigenous American ancestry are at increased risk of intrahepatic cholestasis of pregnancy (ICP), relative to women of other ethnicities. We hypothesized that ancestry-related genetic factors contribute to this increased risk. We collected clinical and laboratory data, and performed biochemical assays on samples from U.S. Latinas and Chilean women, with and without ICP. The study sample included 198 women with ICP (90 from California, U.S., and 108 from Chile) and 174 pregnant control women (69 from California, U.S., and 105 from Chile). SNP genotyping was performed using Affymetrix arrays. We compared overall genetic ancestry between cases and controls, and used a genome-wide admixture mapping approach to screen for ICP susceptibility loci. We identified commonalities and differences in features of ICP between the 2 countries and determined that cases had a greater proportion of Indigenous American ancestry than did controls (p = 0.034). We performed admixture mapping, taking country of origin into account, and identified one locus for which Native American ancestry was associated with increased risk of ICP at a genome-wide level of significance (P = 3.1 x 10(-5), Pcorrected = 0.035). This locus has an odds ratio of 4.48 (95% CI: 2.21-9.06) for 2 versus zero Indigenous American chromosomes. This locus lies on chromosome 2, with a 10 Mb 95% confidence interval which does not contain any previously identified hereditary 'cholestasis genes.' Our results indicate that genetic factors contribute to the risk of developing ICP in the Americas, and support the utility of clinical and genetic studies of ethnically mixed populations for increasing our understanding of ICP.

A comparison of cataloged variation between International HapMap Consortium and 1000 Genomes Project data.

PubMed

Buchanan, Carrie C; Torstenson, Eric S; Bush, William S; Ritchie, Marylyn D

2012-01-01

Since publication of the human genome in 2003, geneticists have been interested in risk variant associations to resolve the etiology of traits and complex diseases. The International HapMap Consortium undertook an effort to catalog all common variation across the genome (variants with a minor allele frequency (MAF) of at least 5% in one or more ethnic groups). HapMap along with advances in genotyping technology led to genome-wide association studies which have identified common variants associated with many traits and diseases. In 2008 the 1000 Genomes Project aimed to sequence 2500 individuals and identify rare variants and 99% of variants with a MAF of <1%. To determine whether the 1000 Genomes Project includes all the variants in HapMap, we examined the overlap between single nucleotide polymorphisms (SNPs) genotyped in the two resources using merged phase II/III HapMap data and low coverage pilot data from 1000 Genomes. Comparison of the two data sets showed that approximately 72% of HapMap SNPs were also found in 1000 Genomes Project pilot data. After filtering out HapMap variants with a MAF of <5% (separately for each population), 99% of HapMap SNPs were found in 1000 Genomes data. Not all variants cataloged in HapMap are also cataloged in 1000 Genomes. This could affect decisions about which resource to use for SNP queries, rare variant validation, or imputation. Both the HapMap and 1000 Genomes Project databases are useful resources for human genetics, but it is important to understand the assumptions made and filtering strategies employed by these projects.

Improved outcome of childhood acute myeloid leukemia in an Eastern European country: Lithuanian experience.

PubMed

Kairiene, Igne; Pasauliene, Ramune; Lipunova, Nadezda; Vaitkeviciene, Goda; Rageliene, Lina; Rascon, Jelena

2017-10-01

The reported treatment outcomes of children treated for cancer in Eastern European countries are inferior to those in Northern/Western Europe. We hypothesized that recent survival rates could be comparable to the current standards and performed a population-based analysis of treatment outcome of childhood acute myeloid leukemia (AML) in Lithuania, a small Eastern European country. Children < 18 years old who were treated for AML from 2000 to 2013 were included (n = 54). Estimates of 5-year event-free (EFS 5y ) and overall survival (OS 5y ) rates were analyzed. Comparing periods 2000-2006 (n = 32) and 2007-2013 (n = 22), the EFS 5y improved from 31 to 63% (p = 0.04), and the OS 5y improved from 31 to 72% (p = 0.02) because of reductions in toxicity-related mortality (42 vs. 15%, p = 0.08) and relapse (43 vs. 25%, p = 0.08). The most significant improvement was demonstrated in high-risk patients (OS 5y improved from 26 to 75%, p = 0.02) who benefited from hematopoietic stem cell transplantation: the post-transplant EFS 5y increased from 13 to 86% (p = 0.01). The current survival rate of Lithuanian children treated for AML was comparable to the expected rate in other parts of Europe. What is Known: • In the last three decades, significant improvement has been achieved in treating childhood cancer, with an overall survival (OS) rate of > 80% in high-income countries. The difference in survival rates between Northern/Western and Eastern European countries as well as between high- and middle-/low-income countries is as much as 20%. Recently, the 5-year event-free survival rate of acute myeloid leukemia (AML) has reached > 60% in high-income countries. The survival rates for myeloproliferative diseases were the lowest in Eastern European countries. • The reported inferior survival rates were calculated based on outcome data of patients treated until 2007. The recent survival rates in Eastern European countries are unknown. What is New: • Being a small Eastern European country, Lithuania has experienced good economic growth during the last decade. We hypothesized that economic growth and gain of experience could result in better survival rates of children treated for cancer in our country in recent years. • A population-based analysis of treatment outcome of childhood AML treated in Lithuania in the recent years was performed for the first time. The survival rates of childhood AML in Lithuania are comparable to those of other high-income countries. Current survival rates of children treated for cancer in Eastern European countries could be comparable to the best current standards contributing to better European survival rates of childhood cancer in general.

Payment for whole blood donations in Lithuania: the risk for infectious disease markers.

PubMed

Kalibatas, V

2008-04-01

In Lithuania, remuneration for whole blood donations still prevails, with the government covering payment for the donors. The payment per donation in cash is equal to 40 litas (euro11.6); it is offered to all blood donors and accepted by the majority of them. Donors who gave blood and received the payment are treated as remunerated donors; those who gave blood and did not take the payment are treated as non-remunerated ones. The purpose of this study was to assess the risk of payment for whole blood donations and to analyse the prevalence of infectious diseases markers per 100 remunerated and non-remunerated, first-time and regular whole blood donations, and to compare the risk ratios of infectious disease markers of remunerated and non-remunerated whole blood donations in 2005 and 2006 at the National Blood Center in Lithuania. Whole blood donors were categorized as follows: (i) first-time donor, remunerated; (ii) first-time donor, non-remunerated; (iii) regular donor, remunerated; and (iv) regular donor, non-remunerated. The blood donations were analysed for the presence or absence of the following infectious disease markers: anti-hepatitis C virus (anti-HCV), hepatitis B surface antigen (HBsAg), anti-human immunodeficiency virus (anti-HIV (1)/(2)) and syphilis. Only confirmed infectious disease markers were classified. To assess the risk of payment for whole blood donations, the prevalence of infectious disease markers per 100 donations in the different donor groups and the risk ratios between the remunerated and non-remunerated donations were determined. The prevalence per 100 first-time remunerated donations was: for anti-HCV 1.84 (2005) and 2.98 (2006); for HBsAg 1.73 (2005) and 2.03 (2006); for syphilis 0.67 (2005) and 1.03 (2006). The prevalence per 100 first-time non-remunerated donations was: for anti-HCV 0.93 (2005) and 0.98 (2006); for HBsAg 1.57 (2005) and 1.33 (2006); for syphilis 0.29 (2005) and 0.47 (2006). The first-time donors who were remunerated for whole blood donations had a significantly higher prevalence of infectious disease markers per 100 donations and a higher risk ratio for at least three infectious disease markers (HBsAg, anti-HCV and syphilis) as compared to first-time donors who were non-remunerated. The regular donors who were non-remunerated for whole blood donations had the lowest prevalence of all infectious disease markers: anti-HCV -0.03 (2005) and 0.04 (2005); syphilis -0.06 (2005) and 0.02 (2006); and any positive cases of HBsAg and anti-HIV (1)/(2) were found both in 2005 and 2006. No statistically significance differences in incidence and risk ratio existed when comparing the regular donations who were remunerated and non-remunerated. The payment for whole blood donors provides a higher risk for infectious disease markers of first-time donations at the National Blood Center in Lithuania.

The Experience of Teachers in the Application of "ActivInspire" Interactive Evaluation System in Classroom: A Case of Teachers in Lithuania

ERIC Educational Resources Information Center

Dudaite, Jolita; Prakapas, Romas

2017-01-01

New technologies are evidently gaining access to daily school life. Considering new challenges, the educators search for new ways to update educational content in the 21st Century when learning paradigms are changing. Soon, the new technological tools and solutions become predominant and change the traditional approach to teaching and learning.…

Vocational Education and Training as a Tool To Ensure Social and Economic Cohesion. National Observatory Country Report. Lithuania, 1999.

ERIC Educational Resources Information Center

Dienys, Vincentas; Beleckiene, Giedre; Zimina, Natalija

The poor state of the Lithuanian economy has led to a diminishing number of jobs and growing number of unemployed. Statistical data make it evident that the poor standard of education is one cause of unemployment. Stages of vocational education and training (VET) are initial, secondary, and postsecondary. The state oversees operation of education…

East European Security After the Cold War

DTIC Science & Technology

1993-01-01

Christian National Union (Poland) ZPL League of Poles in Lithuania vi ."• ... almpter One INTRODUCION More than two decades ago, Zbignlew Brzezinski ...which Brzezinski drew inspiration captures even more aptly and poignantly Eastern Europe’s current security dilemma. Eastern Europe today is...new Defense Minister, Admiral Piotr Kolodziejczyk. has close ties to President Walesa and was Defense Minister in the Mazowiecki government (1990

Iraq: Post-Saddam Governance and Security

DTIC Science & Technology

2008-09-08

territory in 1918 . Britain had tried to take Iraq from the Ottomans earlier in World War I but were defeated at Al Kut in 1916. Britain’s presence in...2007 because $7.2 billion not approved by Iraqi government. Sources: CIA The World Factbook; State Department International Religions Freedom Report...Diwaniyah and includes forces from the following foreign countries: Armenia, Slovakia, Denmark, El Salvador, Ukraine, Romania , Lithuania, Latvia, Mongolia

Blood donors' motivation and attitude to non-remunerated blood donation in Lithuania

PubMed Central

Buciuniene, Ilona; Stonienë, Laimutë; Blazeviciene, Aurelija; Kazlauskaite, Ruta; Skudiene, Vida

2006-01-01

Background In the Soviet period, the blood donation system operated in Lithuania exclusively on a remunerative basis. After joining the EU, Lithuania committed itself to meeting the EU requirements to provide all consumers within its boundaries with safe blood products made from voluntary unpaid blood donations. However, the introduction of a non-remunerated donation system may considerably affect donors' motivation and retention. Thus the aim of the current research was to determine blood donation motives among the present donors and investigate their attitude towards non-remunerated donation. Methods A questionnaire survey of 400 blood donors. Survey data processed using SPSS statistical analysis package. Statistical data reliability checked using Fisher's exact test (p < 0.05). Results Paid donors comprised 89.9%, while non-paid ones made 10.1% of the respondents. Research findings show that 93 per cent of the paid donors give blood on a regular basis; while among the non-remunerated donors the same figure amounted merely to 20.6 per cent. The idea of the remuneration necessity is supported by 78.3 per cent of the paid donors, while 64.7 per cent of the non-remunerated respondents believe that remuneration is not necessary. The absolute majority of the paid donors (92%) think they should be offered a monetary compensation for blood donation, while more than half of the non-remunerated donors (55.9) claim they would be content with a mere appreciation of the act. Provided no remuneration were offered, 28.44 per cent of the respondents would carry on doing it, 29.6 per cent would do it only in emergency, 29.6 per cent would donate blood merely for their family or friends, and 12.3 per cent would quit it completely. Conclusion Most respondents admitted having donated blood for the following reasons: willingness to help the ill or monetary compensation. Majority would consent to free blood donation only in case of emergency or as a family replacement, which leads to a conclusion that provided monetary remuneration is completely terminated part of the currently active paid donors would withdraw from this activity, which might seriously affect the national supply of blood and its products. PMID:16792814

Determinants of self-rated health in elderly populations in urban areas in Slovenia, Lithuania and UK: findings of the EURO-URHIS 2 survey.

PubMed

Stanojevic Jerkovic, Olivera; Sauliune, Skirmante; Šumskas, Linas; Birt, Christopher A; Kersnik, Janko

2017-05-01

Ageing imposes extra financial burdens on social and health services in developed countries. Self-rated health (SRH) is considered to be both a reliable measurement of overall health status including morbidity and mortality and an important predictor of hospitalization, functional impairment and greater demand for health-care services in the elderly. Our aim was to identify factors associated with poor SRH in elderly populations and investigate possible differences between urban areas in Slovenia, Lithuania and UK. Data were obtained from population-based surveys from the European Urban Health Indicator System Part 2 project. The stratified representative sample (41% men and 59% women) consisted of a total of 2547 respondents aged ≥65 from the urban areas in the three countries. The prevalence of poor SRH was highest in Lithuanian urban areas. The strongest factors associated with poor SRH were low education [OR (odds ratio) 4.3, 95% CI (confidence interval) 2.5-7.3, P < 0.001], restriction of activities attributable to a chronic disease (OR 2.6, 95% CI 2.2-3.0, P < 0.001), inadequate physical activity (OR 1.7, 95% CI 1.2-2.5, P = 0.007) and poor mental health (OR 1.1, 95% CI 1.1-1.2, P < 0.001). The main factors associated with poor SRH by country included the following: living alone (Slovenia) (OR 2.0, 95% CI 1.1-3.7, P = 0,023), female sex (Lithuania) (OR 2.0, 95% CI 1.0-4.2, P = 0.058) and inadequate physical activity (UK) (OR 2.2, 95% CI 1.3-3.6, P = 0,003). Despite different levels of poor SRH, the factors associated with poor SRH were similar for the urban areas of the three countries. Factors associated with poor SRH in the urban areas could also reflect either cultural differences or specific situations for elderly in that country, which need further research. © The Author 2015. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

Sustainable development of deep-water seaport: the case of Lithuania.

PubMed

Burskyte, Vilma; Belous, Olga; Stasiskiene, Zaneta

2011-06-01

In 2003, the Japan International Cooperation Agency carried out a development feasibility study of Klaipeda Seaport (Lithuania). The focus in this study was the evaluation of environmental impacts of the port expansion because it is located in an ecologically sensitive area. While the Japanese researchers focused on the environmental impact analysis, they did not provide unambiguous conclusions. The problems remained unresolved and required further, more detailed consideration and deeper analysis. Environmental sustainability in seaports is an issue of timely importance in many countries given the rapid increase in port-to-port traffic and harbor capacity. This paper explores the situation in Klaipeda Seaport (Lithuania) which is the northernmost ice-free port on the Eastern coast of the Baltic Sea and its challenges in terms of environmental aspects and current pollution situation. This port plays an important role in the economic development of the region and in creating a sustainable society, i.e., a society that continues to develop economically without increasing its impact on our living environment and where the possible reduction of its current impact can be huge due to the fact that the seaport is a place where transport and logistics intersect and constitute large-scale industrial estates. Increasingly, they also turn towards sustainability. Society faces the need for radical change because of increasing technological progress and increasing environmental impact. Environmental and public issues must be addressed by a systemic approach to find harmony among all the subsystems. Therefore, the authors of the article performed an assessment of the deep-water port of Klaipeda sustainable development opportunities tackling the following tasks: (1) Assessing Klaipeda port and the projected deep-water port of the current environment state; (2) Assessing the impact of the water quality of Klaipeda port, depending on the intensity of activity; (3) Assessing the projected impact of the deep-water port on the environment. The results of the performed research allowed: (a) to reveal strengths and weaknesses of Klaipeda port development and the potential conflicts of interest among different stakeholders, (b) to identify the set of problem solutions seeking sustainable Klaipeda port development; (c) to develop the set of sustainability indicators to monitor the efficiency of the development.

[Laparoscopic surgery for malignancies of the colon, rectum, and anus in Lithuania in 2008].

PubMed

Samalavicius, Narimantas Evaldas; Rudinskaite, Giedre; Pavalkis, Dainius; Latkauskas, Tadas; Kaselis, Nerijus; Sidlauskas, Zilvinas; Sniuolis, Pranas; Poskus, Tomas; Kvedaras, Vytautas; Strupas, Kestutis; Poskus, Eligijus

2009-01-01

THE OBJECTIVE OF THIS STUDY: was to analyze data on laparoscopic surgery for malignant diseases of the colon, rectum, and anus in Lithuania during the period of January 1, 2005, to February 15, 2008. During the above-mentioned period in Lithuania, 130 laparoscopic surgeries for malignancies of colon, rectum, and anus were performed in seven different hospitals. There were 73 males and 57 females with a mean age of 68 years (range, 35-85 years). Laparoscopic procedures were attempted in 140 cases. Out of them, 130 were completed laparoscopically; 10 operations were converted to open, and conversion rate was 7.1%. Twenty-seven (20.8%) patients had stage I, 45 (34.6%) stage II, 45 (34.6%) stage III, and 13 (10%) stage IV disease. Ninety-two (70.8%) patients underwent straight laparoscopic surgery and 38 (29.2%) - hand-assisted laparoscopic surgery. Time in surgery was from 50 to 365 min, with a mean of 183 min. During 130 operations, in 11 (8.5%) cases, blood vessels were ligated through specimen retrieval site. Out of 104 operations, where anastomosis was performed (23 abdominoperineal resections and 3 Hartmann's procedures), in 68 (65.4%) cases it was done laparoscopically and in 36 (34.6%) cases using conventional extracorporal suturing. Hospital stay ranged from 7 to 59 days, with a mean of 12 days. One (0.8%) patient died. Postoperative complications occurred in 27 (20.8%) cases. Reoperation rate was 4.6% (6 cases). Complications were as follows: suture insufficiency (3 cases), eventration (3 cases), wound infection (7 cases), intraperitoneal abscess (1 case), abdominal wall phlegmon (1 case), intra-abdominal infiltrate (1 case), perineal hematoma (1 case), proctovaginal fistula (2 case), intraoperative bleeding from uterus (1 case), urinary retention (4 cases), cystitis (1 case), pneumonia (1 case), acute cardiovascular insufficiently (1 case). In histological specimens, 10 lymph nodes were found on the average (range, 2 to 27). Laparoscopic surgery for malignant diseases of the colon, rectum, and anus is dominating among laparoscopic surgeries for colorectum. Complication rate is similar to other authors. To evaluate disease relapse and outcomes, observation time is not sufficient yet.

Fine-touch pressure thresholds in the adult penis.

PubMed

Sorrells, Morris L; Snyder, James L; Reiss, Mark D; Eden, Christopher; Milos, Marilyn F; Wilcox, Norma; Van Howe, Robert S

2007-04-01

To map the fine-touch pressure thresholds of the adult penis in circumcised and uncircumcised men, and to compare the two populations. Adult male volunteers with no history of penile pathology or diabetes were evaluated with a Semmes-Weinstein monofilament touch-test to map the fine-touch pressure thresholds of the penis. Circumcised and uncircumcised men were compared using mixed models for repeated data, controlling for age, type of underwear worn, time since last ejaculation, ethnicity, country of birth, and level of education. The glans of the uncircumcised men had significantly lower mean (sem) pressure thresholds than that of the circumcised men, at 0.161 (0.078) g (P = 0.040) when controlled for age, location of measurement, type of underwear worn, and ethnicity. There were significant differences in pressure thresholds by location on the penis (P < 0.001). The most sensitive location on the circumcised penis was the circumcision scar on the ventral surface. Five locations on the uncircumcised penis that are routinely removed at circumcision had lower pressure thresholds than the ventral scar of the circumcised penis. The glans of the circumcised penis is less sensitive to fine touch than the glans of the uncircumcised penis. The transitional region from the external to the internal prepuce is the most sensitive region of the uncircumcised penis and more sensitive than the most sensitive region of the circumcised penis. Circumcision ablates the most sensitive parts of the penis.

Midlife Hypertensive Status and Cognitive Function 20 Years Later: The Southall and Brent Revisited Study

PubMed Central

Taylor, Clare; Tillin, Therese; Chaturvedi, Nish; Dewey, Michael; Ferri, Cleusa P; Hughes, Alun; Prince, Martin; Richards, Marcus; Shah, Ajit; Stewart, Robert

2013-01-01

Objectives: To investigate long-term prospective associations between a range of measurements of hypertensive status in midlife and cognitive impairment 20 years later. Design: Cohort study. Setting: Two areas (Southall and Brent) of northwest London. Participants: Survey samples of a multiethnic population (European, African Caribbean, South Asian) aged 40 to 67 were followed up 20 years later. Measurements: Comprehensive cardiovascular assessments were performed at baseline, including measurements of resting blood pressure (BP) and, in a subsample, ambulatory BP. At follow-up, a battery of cognitive assessments was administered, and a composite outcome was derived, with impairment defined as the lowest 10% within each ethnic group. Logistic regression models were used to investigate associations with prior measures of hypertensive status. Results: In 1,484 participants at follow-up, cognitive impairment showed significant U-shaped associations with baseline diastolic BP (DBP) and mean arterial pressure (MAP; strongest for those aged ≥50 at baseline), independent of a range of covariates, but no associations were found with systolic BP or pulse pressure. Cognitive impairment was also associated with antihypertensive medication use and higher evening ambulatory DBP at baseline. No substantial differences in strengths of association were found between ethnic groups. Conclusion: Low and high DBP and MAP were associated with cognitive impairment 20 years later. Higher evening DBP on ambulatory monitoring was also associated with greater risk. PMID:24028355

Mapping Urban Risk: Flood Hazards, Race, & Environmental Justice In New York”

PubMed Central

Maantay, Juliana; Maroko, Andrew

2009-01-01

This paper demonstrates the importance of disaggregating population data aggregated by census tracts or other units, for more realistic population distribution/location. A newly-developed mapping method, the Cadastral-based Expert Dasymetric System (CEDS), calculates population in hyper-heterogeneous urban areas better than traditional mapping techniques. A case study estimating population potentially impacted by flood hazard in New York City compares the impacted population determined by CEDS with that derived by centroid-containment method and filtered areal weighting interpolation. Compared to CEDS, 37 percent and 72 percent fewer people are estimated to be at risk from floods city-wide, using conventional areal weighting of census data, and centroid-containment selection, respectively. Undercounting of impacted population could have serious implications for emergency management and disaster planning. Ethnic/racial populations are also spatially disaggregated to determine any environmental justice impacts with flood risk. Minorities are disproportionately undercounted using traditional methods. Underestimating more vulnerable sub-populations impairs preparedness and relief efforts. PMID:20047020

A comparison of cataloged variation between International HapMap Consortium and 1000 Genomes Project data

PubMed Central

Buchanan, Carrie C; Torstenson, Eric S; Bush, William S

2012-01-01

Background Since publication of the human genome in 2003, geneticists have been interested in risk variant associations to resolve the etiology of traits and complex diseases. The International HapMap Consortium undertook an effort to catalog all common variation across the genome (variants with a minor allele frequency (MAF) of at least 5% in one or more ethnic groups). HapMap along with advances in genotyping technology led to genome-wide association studies which have identified common variants associated with many traits and diseases. In 2008 the 1000 Genomes Project aimed to sequence 2500 individuals and identify rare variants and 99% of variants with a MAF of <1%. Methods To determine whether the 1000 Genomes Project includes all the variants in HapMap, we examined the overlap between single nucleotide polymorphisms (SNPs) genotyped in the two resources using merged phase II/III HapMap data and low coverage pilot data from 1000 Genomes. Results Comparison of the two data sets showed that approximately 72% of HapMap SNPs were also found in 1000 Genomes Project pilot data. After filtering out HapMap variants with a MAF of <5% (separately for each population), 99% of HapMap SNPs were found in 1000 Genomes data. Conclusions Not all variants cataloged in HapMap are also cataloged in 1000 Genomes. This could affect decisions about which resource to use for SNP queries, rare variant validation, or imputation. Both the HapMap and 1000 Genomes Project databases are useful resources for human genetics, but it is important to understand the assumptions made and filtering strategies employed by these projects. PMID:22319179

A State Partnership Program (SPP) for Afghanistan

DTIC Science & Technology

2009-03-01

former eastern bloc countries (Estonia, Latvia, Lithuania ) that emerged from the Cold War independent, but potentially precarious following the fall of the...asserts the necessity to “engage and involve the private sector in reconstruction” and also “to secure and protect the natural resources, energy production ...military working dogs , and combat lifesaver training amongst many38 15 An increasingly important country in terms of CENTCOM’s security cooperation

Enhancing the Role of Social Partner Organisations in the Area of Vocational Education and Training in the Candidate Countries of Central and Eastern Europe. Institutional Arrangements. Report.

ERIC Educational Resources Information Center

European Training Foundation, Turin (Italy).

The role of social partner organizations in vocational education and training (VET) has been compared for Bulgaria, Czech Republic, Estonia, Hungary, Latvia, Lithuania, Poland, Romania, the Slovak Republic, and Slovenia. In these countries, a system of industrial relations comparable to those existing in western Europe is emerging gradually.…

An Educology of Values Education: The Attitudes of Thirteen to Fifteen Year Old Teenagers Towards Spiritual Values--Priorities, Change and Some Pre-Conditions

ERIC Educational Resources Information Center

Martisauskiene, Elvyda

2002-01-01

An analysis was conducted in Lithuania of teenager attitudes towards spiritual values which function in both micro- and macro-environments. The data obtained in this contemporary investigation were compared with those registered two decades ago, in the authoritarian type of society of that time. The focus of the study is on the peculiarities of…

Environmental Engagement Success Utilizing Reachback Support

DTIC Science & Technology

2012-05-24

Georgia •Kosovo •Moldova • Montenegro •Norway •Romania •Russia •Sweden 24 May 2012 - 7 UNCLASSIFIED $0 $100,000 $200,000 $300,000 $400,000...Bulgaria $770K Serbia $500K Macedonia $1.3M Kosovo $950K Montenegro $2.4M Albania $900K Bosnia $500K Lithuania $815K Latvia...treatment plants Sustainable energy Sustainable design 24 May 2012 - 14 UNCLASSIFIED BPC DOD Strategy Project Development Country

Report on Progress Toward Security and Stability in Afghanistan

DTIC Science & Technology

2013-07-01

Finland : 3 UK: 13 Croatia: 4 Hungary: 3 Italy: 22 Lithuania: 2 Netherlands: 6 Poland: 9 Portugal: 1 Romania: 3 Slovenia: 1 Slovakia: 1...civilian casualties resulting from operations by pro -government forces compared with the same period in 2011, and more specifically, a 42 percent...Window A is administered by the World Bank; contributors are Australia ($5.9 million), Finland ($2.5 million), and the United States ($50 million

Iraq: Post-Saddam Governance and Security

DTIC Science & Technology

2008-08-12

took control of the territory in 1918 . Britain had tried to take Iraq from the Ottomans earlier in World War I but were defeated at Al Kut in 1916... Religions Freedom Report, September 2007; DOD Measuring Stability Report, June 2008. CRS-3 1 Bush, George H.W., and Brent Scowcroft. A World Transformed...Armenia, Slovakia, Denmark, El Salvador, Ukraine, Romania , Lithuania, Latvia, Mongolia, and Kazakhstan. Polish forces number 900, down from a high

Local Wisdom of The Native Settlement as A Main Gate in The Northern Axis of Javanese City Center In Semarang

NASA Astrophysics Data System (ADS)

Siti Rukayah, R.; Respati Puguh, Dhanang, Dr; Sri Susilo, Endang; Sahid Indraswara, Mohammad

2018-05-01

Similar to the city structure of Islamic cities in Java, Semarang also has multi-ethnic kampongs located around alun-alun / traditional square. There is a uniqueness kampong ethnic village that was located in the coastal city of Semarang. Now there are no longer in coastal area. Based on historical method using some old maps and the old images and field study resulted that the old city centre of Semarang had a north axis connecting the seaport (Kampung Darat - 14th century) to the alun-alun as administrative city centre (16th century). The axis was once a commercial corridor with settlements arrays behind the commercial corridor. There is some local wisdom in the settlement arrangement. The economic and religious harmonies live together along the corridor. The ethnic Chinese and Arabs as a merchant set up shop houses in the corridor that had a strategic value. Meanwhile, Malay, Arab, Cirebon and Banjar settlements located behind commercial corridors. This corridor present that the economic activity dominated done by Arabic and Chinese trader. Local wisdom in urban design heritage along North axis functioned as main gate to traditional city centre. The local wisdom is potential to be integrated with recent situation and replicated in another region

A comprehensive profile of DNA copy number variations in a Korean population: identification of copy number invariant regions among Koreans.

PubMed

Jeon, Jae Pil; Shim, Sung Mi; Jung, Jong Sun; Nam, Hye Young; Lee, Hye Jin; Oh, Berm Seok; Kim, Kuchan; Kim, Hyung Lae; Han, Bok Ghee

2009-09-30

To examine copy number variations among the Korean population, we compared individual genomes with the Korean reference genome assembly using the publicly available Korean HapMap SNP 50 k chip data from 90 individuals. Korean individuals exhibited 123 copy number variation regions (CNVRs) covering 27.2 mb, equivalent to 1.0% of the genome in the copy number variation (CNV) analysis using the combined criteria of P value (P<0.01) and standard deviation of copy numbers (SD>or= 0.25) among study subjects. In contrast, when compared to the Affymetrix reference genome assembly from multiple ethnic groups, considerably more CNVRs (n=643) were detected in larger proportions (5.0%) of the genome covering 135.1 mb even by more stringent criteria (P<0.001 and SD>or=0.25), reflecting ethnic diversity of structural variations between Korean and other populations. Some CNVRs were validated by the quantitative multiplex PCR of short fluorescent fragment (QMPSF) method, and then copy number invariant regions were detected among the study subjects. These copy number invariant regions would be used as good internal controls for further CNV studies. Lastly, we demonstrated that the CNV information could stratify even a single ethnic population with a proper reference genome assembly from multiple heterogeneous populations.

Associations Between Genetic Ancestries and Nicotine Metabolism Biomarkers in the Multiethnic Cohort Study

PubMed Central

Wang, Hansong; Park, Sungshim L.; Stram, Daniel O.; Haiman, Christopher A.; Wilkens, Lynne R.; Hecht, Stephen S.; Kolonel, Laurence N.; Murphy, Sharon E.; Le Marchand, Loïc

2015-01-01

Differences in internal dose of nicotine and tobacco-derived carcinogens among ethnic/racial groups have been observed. In this study, we explicitly examined the relationships between genetic ancestries (genome-wide average) and 19 tobacco-derived biomarkers in smokers from 3 admixed groups in the Multiethnic Cohort Study (1993–present), namely, African ancestry in African Americans (n = 362), Amerindian ancestry in Latinos (n = 437), and Asian and Native Hawaiian ancestries in Native Hawaiians (n = 300). After multiple comparison adjustment, both African and Asian ancestries were significantly related to a greater level of free cotinine; African ancestry was also significantly related to lower cotinine glucuronidation (P's < 0.00156). The predicted decrease in cotinine glucuronidation was 8.6% (P = 4.5 × 10−6) per a 20% increase in African ancestry. Follow-up admixture mapping revealed that African ancestry in a 12-Mb region on chromosome 4q was related to lower cotinine glucuronidation (P's < 2.7 × 10−7, smallest P = 1.5 × 10−9), although this is the same region reported in our previous genome-wide association study. Our results implicate a genetic ancestral component in the observed ethnic/racial variation in nicotine metabolism. Further studies are needed to identify the underlying genetic variation that could potentially be ethnic/racial specific. PMID:26568573

Indoor thermal environment, air exchange rates, and carbon dioxide concentrations before and after energy retro fits in Finnish and Lithuanian multi-family buildings.

PubMed

Leivo, Virpi; Prasauskas, Tadas; Du, Liuliu; Turunen, Mari; Kiviste, Mihkel; Aaltonen, Anu; Martuzevicius, Dainius; Haverinen-Shaughnessy, Ulla

2018-04-15

Impacts of energy retrofits on indoor thermal environment, i.e. temperature (T) and relative humidity (RH), as well as ventilation rates and carbon dioxide (CO 2 ) concentrations, were assessed in 46 Finnish and 20 Lithuanian multi-family buildings, including 39 retrofitted case buildings in Finland and 15 in Lithuania (the remaining buildings were control buildings with no retrofits). In the Finnish buildings, high indoor T along with low RH levels was commonly observed both before and after the retrofits. Ventilation rates (l/s per person) were higher after the retrofits in buildings with mechanical exhaust ventilation than the corresponding values before the retrofits. Measured CO 2 levels were low in vast majority of buildings. In Lithuania, average indoor T levels were low before the retrofits and there was a significant increase in the average T after the retrofits. In addition, average ventilation rate was lower and CO 2 levels were higher after the retrofits in the case buildings (N=15), both in apartments with natural and mixed ventilation. Based on the results, assessment of thermal conditions and ventilation rates after energy retrofits is crucial for optimal indoor environmental quality and energy use. Copyright © 2017 Elsevier B.V. All rights reserved.

Self-reported oral health behavior and attitudes of dental and technology students in Lithuania.

PubMed

Pacauskiene, Ingrida M; Smailiene, Dalia; Siudikienė, Jolanta; Savanevskyte, Julija; Nedzelskiene, Irena

2014-01-01

The aim of the present study was to assess self-reported oral health habits, attitudes, lifestyle between the sample groups of preclinical and clinical dental and technology students in Lithuania using the Hiroshima University Dental Behavioral Inventory (HU-DBI), and to evaluate the impact of education on their behavior and self-reported oral health. A sample of 183 dental and 75 technology students at the Lithuanian University of Health Sciences, Medical Academy, Faculty of Odontology, and Kaunas University of Technology completed the Lithuanian version the HU-DBI questionnaire with 11 additional items. The data were analyzed using the "SPSS 19.0 for Windows" software package. The mean HU-DBI score of clinical final-year dentistry students was significantly higher (p=0.001) than the score of the preclinical group (6.81 (1.2) and 5.96 (1.5), respectively). The mean scores of both groups of dental students were significantly (p<0.05) higher than that of the technology group (5.37 (1.8)). Oral health behaviors and knowledge were superior in dental students. Dental education had a significant positive impact on the oral health and behavior improvement. The attitudes of the Lithuanian dental students should be further improved by initiating a comprehensive program that would emphasize the importance of oral hygiene before the clinical program starts.

Radiological and archaeological investigation of a mummy from Roman Egypt curated in the National Museum of Lithuania.

PubMed

Piombino-Mascali, Dario; Jankauskas, Rimantas; Snitkuvienė, Aldona; Rutkauskas, Tadas; Sutherland, M Linda

2016-01-01

Among the collections belonging to the National Museum of Lithuania at Vilnius, resides an ancient Egyptian coffin containing a mummified human body. The coffin and its occupant are believed to have belonged to the King of Poland and to have been located in his palace at Warsaw. At the turn of the last century, Egyptologists dated the coffin to the end of the 21st dynasty (1070 BC-945 BC), and described the item as coming from Thebes, belonging to Hori, priest of Amun-Ra. However, no investigation was ever carried out on the human body associated with the coffin. Within the framework of the Lithuanian Mummy Project, the preserved human remains underwent computed tomographic investigation in order to reconstruct the biological profile of the subject and to determine the embalming method employed. This led to the identification of a young adult male. Additionally, the mummy shroud was stylistically assessed in order to determine the mummy's chronology in Egyptian history. Interestingly, the body could be ascribed to the Roman period of Egypt (30 BC-395 AD) due to analogies with the burial shrouds of the Soter group. This indicates a reuse of the coffin at some point in history.

Late-Holocene vegetation dynamics in response to a changing climate and anthropogenic influences - Insights from stratigraphic records and subfossil trees from southeast Lithuania

NASA Astrophysics Data System (ADS)

Edvardsson, Johannes; Stančikaitė, Miglė; Miras, Yannick; Corona, Christophe; Gryguc, Gražyna; Gedminienė, Laura; Mažeika, Jonas; Stoffel, Markus

2018-04-01

To increase our understanding of long-term climate dynamics and its effects on different ecosystems, palaeoclimatic and long-term botanical reconstructions need to be improved, in particular in underutilized geographical regions. In this study, vegetation, (hydro)climate, and land-use changes were documented at two southeast Lithuanian peatland complexes - Čepkeliai and Rieznyčia - for the Late-Holocene period. The documentation was based on a combination of pollen, plant macrofossils, peat stratigraphic records, and subfossil trees. Our results cover the last two millennia and reveal the existence of moist conditions in Southern Lithuania between 300 and 500 CE and from 950 to 1850 CE. Conversely, changes towards warmer and/or dryer conditions have been recorded in 100, 600, and 750 CE, and since the 1850s. Significant differences with other Baltic proxies prevent deriving a complete and precise long-term reconstruction of past hydroclimatic variability at the regional scale. Yet, our results provide an important cornerstone for an improved understanding of regional climate change, i.e. in a region for which only (i) few detailed palaeobotanical studies exist and which has, in addition, been considered as (ii) an ecologically sensitive region at the interface between the temperate and boreal bioclimatic zones.

The role of the European Structural and Investment Funds in Financing Health System in Lithuania: Experience from 2007 to 2013 funding period and implications for the future.

PubMed

Murauskiene, Liubove; Karanikolos, Marina

2017-07-01

European Structural and Investment Funds (ESIF) are a major source of investments in the newer EU member states. In Lithuania's health sector, the amount for the 2007-2013 funding period reached more than €400 million. In this paper we aim to (i) identify the key areas in the health sector which were supported by ESIF, (ii) determine the extent to which ESIF assisted the implementation of the ongoing health system reform; and (iii) assess whether the use of funds has led to expected improvements in healthcare. We review the national strategic documents and legislation, and perform calculations to determine funding allocations by specific area, based on the available data. We analyse changes according to a set of selected indicators. We find that implementation of programmes funded by the ESIF lacks formal evaluation. Existing evidence suggests that some improvement has been achieved by 2013. However, there are persisting challenges, including failure to reach a broad agreement on selection of health and healthcare indicators, lack of transparency in allocations, and absence of coherent assessment measures of healthcare quality and accessibility. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

Eye healthcare services in eastern Europe: Part 1. Cataract surgery.

PubMed

Kocur, I; Resnikoff, S; Foster, A

2002-08-01

To describe cataract surgical services in 1998 in 12 eastern European countries and to identify their needs to reduce cataract blindness. All inpatient eye departments in the 12 countries received a standardised questionnaire; the data obtained were further processed at the coordinating centre in Prague. All 458 eye departments in the region were involved. The response rate was 100%, except for Bulgaria (93%) and Romania (93%). The total number of cataract surgeries per one million inhabitants in 1998 was calculated: Belarus (800), Federation of Bosnia and Herzegovina (1275), Bulgaria (1730), the Czech Republic (4210), Estonia (2530), Hungary (3530), Latvia (1860), Lithuania (1550), Trans-Dniester Moldova (1300), Poland (1475), Romania (1260), and Slovakia (2430). Cataracts were mostly operated on by the extracapsular technique. Intracapsular extractions were frequently performed in Federation of Bosnia and Herzegovina (47%), Belarus (46%), Bulgaria (18%), and Romania (14.3%). Phacoemulsification was uncommonly used in 1998, except for the Czech Republic (86%), Estonia (50%), Slovakia (38%), and Hungary (16%). An IOL was implanted in more than 90% of patients in the Czech Republic, Estonia, Hungary, Latvia, Lithuania, and Slovakia. Conditions for cataract surgery in the eastern European region differ. The main barriers to cataract surgery were state budget limitations, insufficient supply of consumables, underutilisation of operating theatres, and poor detection of patients requiring surgery.

Experimental Infection of Domestic Pigs with African Swine Fever Virus Lithuania 2014 Genotype II Field Isolate.

PubMed

Gallardo, C; Soler, A; Nieto, R; Cano, C; Pelayo, V; Sánchez, M A; Pridotkas, G; Fernandez-Pinero, J; Briones, V; Arias, M

2017-02-01

An experimental infection was conducted to evaluate horizontal transmission, clinical, virological and humoral response induced in domestic pigs infected with African swine fever (ASF) genotype II virus circulating in 2014 into the European Union (EU). Ten naive pigs were placed in contact with eight pigs experimentally inoculated with the Lithuanian LT14/1490 ASF virus (ASFV) responsible for the first ASF case detected in wild boar in Lithuania in January 2014. Clinical examination and rectal temperature were recorded each day. Blood sampling from every animal was carried out twice weekly. Blood samples were examined for presence of ASF virus-specific antibodies and for determining the ASFV viral load. From the obtained results, it was concluded that the Lithuanian ASFV induced an acute disease which resulted in 94, 5% mortality. The disease was easily detected by real-time PCR prior to the onset of clinical signs and 33% of the animals seroconverted. All findings were in accordance with observations previously made in domestic pigs and wild boar when infected with ASF genotype II viruses characterized by a high virulence. One in-contact pig remained asymptomatic and survived the infection. The role of such animals in virus transmission would need further investigation. © 2015 Blackwell Verlag GmbH.

Factors associated with Listeria monocytogenes contamination of cold-smoked pork products produced in Latvia and Lithuania.

PubMed

Bērziņs, Aivars; Hörman, Ari; Lundén, Janne; Korkeala, Hannu

2007-04-10

A total of 312 samples of sliced, vacuum packaged, cold-smoked pork from 15 meat processing plants in Latvia and Lithuania, obtained over a 15-month period from 2003 until 2004, were analyzed for the presence of Listeria monocytogenes at the end of their shelf-life. Overall, 120 samples (38%) tested positive for L. monocytogenes. Despite the long storing period, the levels of L. monocytogenes in cold-smoked pork products were low. Manufacturing processes were studied at seven meat processing plants. A new approach with a logistic multivariable regression model was applied to identify the main factors associated with L. monocytogenes contamination during the manufacturing of cold-smoked pork products. Brining by injection was a significant factor (odds ratio 10.66; P<0.05) for contamination of product with L. monocytogenes. Moreover, long cold-smoking times (> or = 12 h) had a significant predictive value (odds ratio 24.38; P<0.014) for a sample to test positive for L. monocytogenes. Pulsed-field gel electrophoresis results indicated that various sources of L. monocytogenes contamination existed over periods of time in several meat processing plants. In two meat processing plants, persistent L. monocytogenes strains belonging to serotypes 1/2a and 1/2c were found.

High resolution skin colorimetry, strain mapping and mechanobiology.

PubMed

Devillers, C; Piérard-Franchimont, C; Schreder, A; Docquier, V; Piérard, G E

2010-08-01

Skin colours are notoriously different between individuals. They are governed by ethnicities and phototypes, and further influenced by a variety of factors including photoexposures and sustained mechanical stress. Indeed, mechanobiology is a feature affecting the epidermal melanization. High-resolution epiluminescence colorimetry helps in deciphering the effects of forces generated by Langer's lines or relaxed skin tension lines on the melanocyte activity. The same procedure shows a prominent laddering pattern of melanization in striae distensae contrasting with the regular honeycomb pattern in the surrounding skin.

Caring for culturally diverse patients: one agency's journey toward cultural competence.

PubMed

Romeo, Cathy

2007-03-01

Across the United States, spanning urban, suburban, and rural areas, racial and ethnic minority populations are growing faster than White English-speaking populations. Increasingly, healthcare professionals are providing care to patients from diverse cultures with traditions and beliefs that may be unfamiliar and with health practices that may conflict with western medicine. How can home care and hospice professionals navigate this new terrain and communicate effectively across cultural boundaries? One agency's journey toward cultural competency may provide a road map for others.

10 Years Later: Changes in Food Access Disparities in New Orleans since Hurricane Katrina.

PubMed

Mundorf, Adrienne R; Willits-Smith, Amelia; Rose, Donald

2015-08-01

Inadequate access to healthy food is a problem in many urban neighborhoods, particularly for racial-ethnic minorities and low-income groups who are more likely to reside in food deserts. Although substantial research throughout the country has documented the existence of these disparities, few studies have focused on how this access changes over time or is affected by environmental shocks. This study examined citywide supermarket access in New Orleans as well as racial-ethnic disparities in this access, prior to Hurricane Katrina and at three times afterwards. On-the-ground verification of supermarket locations was conducted in 2004-2005, 2007, 2009, and 2014 and was mapped with secondary demographic data. Census tracts were defined as predominantly African-American neighborhoods if 80 % or more of the population identified as such. HLM Poisson regression analyses were conducted in 2014 to identify the difference in likelihood of finding supermarkets in a neighborhood by race-ethnicity and across all years of interest. Racial-ethnic disparities existed before the storm and worsened after it (IRR = 0.35; 95 % CI = 0.21, 0.60). Improvements in disparities to pre-storm levels were not seen until 2009, 4 years after the storm. By 2014, supermarket access, on average, was not significantly different in African-American neighborhoods than in others (IRR = 0.90; 95 % CI = 0.65, 1.26). The slow recovery of New Orleans' retail food infrastructure after Hurricane Katrina highlights the need for an increased focus on long-term planning to address disparities, especially those that may be exaggerated by shocks.

Verification of a Schumann Resonance Inversion Method for Global Lightning Activity in Absolute Units

NASA Astrophysics Data System (ADS)

Williams, E. R.; Guha, A.; Liu, Y.; Boldi, R. A.; Pracser, E.; Said, R.; Satori, G.; Bozoki, T.; Bor, J.; Atkinson, M.; Beggan, C.; Cummer, S.; Lyu, F.; Fain, B.; Hobara, Y.; Alexander, K.; Kulak, A.; McCraty, R.; Mlynarczyk, J.; Montanya, J.; Moore, R. C.; Neska, M.; Ortega, P.; Price, C. G.; Rawat, R.; Sato, M.; Sinha, A. K.; Yampolski, Y.

2017-12-01

The global reach of single, calibrated ELF receivers operating in the Schumann resonance (SR) band (3-50 Hz) has been verified by global maps of energetic Q-burst locations and vertical charge moment change, and by locations of independently verified transient luminous events in a wide variety of locations worldwide. It has also been previously shown that with as few as six ELF receivers in widely separated locations, multi-station, multi-modal SR parameters extracted from the SR "background" signal can be inverted to provide the centroid locations of continental lightning "chimneys" (Asia, Africa, Americas) and their respective lightning activities in absolute units (coul2 km2/sec). This inversion method involves a propagation model for the Earth-ionosphere cavity with day-night asymmetry. The Earth is now populated with more than 30 calibrated ELF receivers making continuous time series observations. This circumstance is exploited in the present study to verify the findings of the ELF inversion method. During the period May 17-20 and 23-24, 2015, two independent sets of nine ELF receivers each, in widely-separated geographical locations (first set: Antarctica (3 sites), Hungary, Japan (2 sites), Poland, Spitzbergen, and USA; second set: Antarctica, Canada, Cape Verde Island, Lithuania, New Zealand, Saudi Arabia, Scotland, Tahiti, and USA), are used to compare the locations and source strengths of lightning chimneys. Detailed comparisons will be shown over Universal Time for selected days.

Population differences in the rate of proliferation of international HapMap cell lines.

PubMed

Stark, Amy L; Zhang, Wei; Zhou, Tong; O'Donnell, Peter H; Beiswanger, Christine M; Huang, R Stephanie; Cox, Nancy J; Dolan, M Eileen

2010-12-10

The International HapMap Project is a resource for researchers containing genotype, sequencing, and expression information for EBV-transformed lymphoblastoid cell lines derived from populations across the world. The expansion of the HapMap beyond the four initial populations of Phase 2, referred to as Phase 3, has increased the sample number and ethnic diversity available for investigation. However, differences in the rate of cellular proliferation between the populations can serve as confounders in phenotype-genotype studies using these cell lines. Within the Phase 2 populations, the JPT and CHB cell lines grow faster (p < 0.0001) than the CEU or YRI cell lines. Phase 3 YRI cell lines grow significantly slower than Phase 2 YRI lines (p < 0.0001), with no widespread genetic differences based on common SNPs. In addition, we found significant growth differences between the cell lines in the Phase 2 ASN populations and the Han Chinese from the Denver metropolitan area panel in Phase 3 (p < 0.0001). Therefore, studies that separate HapMap panels into discovery and replication sets must take this into consideration. Copyright © 2010 The American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

Palaeoproterozoic Volcanic Massive Sulphides (VMS) in the Lithuanian crystalline basement: evidences for a back-arc tectonic setting

NASA Astrophysics Data System (ADS)

Skridlaite, Grazina; Siliauskas, Laurynas

2014-05-01

In the southwestern part of the East European Craton (EEC), several events of Palaeoproterozoic volcanic arc magmatic activity were recognized in the concealed crystalline basement. In Lithuania, the TTG suites of 1.89 Ga and 1.86-1.84 Ga were later metamorphosed in amphibolite and granulite facies conditions. Remnants of a volcano-sedimentary sequence metamorphosed in green schist and amphibolite facies conditions were discovered in central and southern Lithuania. In southern Lithuania, the upper part of the Lazdijai 13 (Lz13) drilling (at c. 493 m depth) consists of exhalitic quartz chlorite cherts mixed with andesitic rocks. The rocks are impregnated with magnetite in some places replacing calcite. Most of the magnetite grains are overgrown by a dendritic kovelite, which may have formed while magnetite was still in aqueous surrounding. Other accessory minerals are xenotime, zircon, apatite, Sr-Ba sulphates etc. The cherts are underlain by a metaandesite which volcanic structures were obscured by hydrothermal alteration, i.e. the idiomorphic magnetite crystals and porphyritic plagioclase grains were replaced by clay minerals and quartz or muscovite in many places. Thin metamorphosed mudstone layers turned into garnet, biotite (+/-staurolite) and chlorite schists. The rocks were affected by silicification, chloritization, argilitization and carbonatization. Taking into account the rock composition, micro and macro scale alteration zones and absence of breccia, the whole package resembles an outer part of the VMS stockwork. The lower boundary at 526 m is sharp, marked by a quartz vein, below which lies quartz, biotite (+/- chlorite) bearing schist with minor tremolite (former sandstone). It was intensely affected by silicification, and was enriched in Na, K and Ca. Accessory minerals are monazite, xenotime, apatite and detrital zircon. The schist exhibits fine mineral foliation, and is fine-grained. A 4 m thick granitic vein cuts the rock at 654 m depth, below which there are amphibolites with layers or lenses of skarns formed in marbles. Some amphibolites resemble porphyritic basalts. These might be dikes of basalts, which are common for back arc VMS surroundings. The volcano-clastic rock from the Lz13 yielded c. 1.83 Ga and c. 1.80 Ga ages. The whole rock Sm-Nd isotopic composition points towards juvenile origin of the rock (TDM=2.08 Ga, ɛNd (1.9) +1.8). After the comparison of the obtained data set with VMS deposits formed in different environments, it is most likely that the volcano-sedimentary sequence of Lz13 was formed in a back arc tectonic setting. The volcano-sedimentary sequence can be correlated with the 1.83 Ga Oskarshamn-Jönköping Belt (Mansfeld et al., 2005) and the volcano-sedimentary Vetlanda formation (Makowsky and Mansfeld, 2013) in southeastern Sweden. The c. 1.83-1.80 Ga volcanic arc and back-arc system continues from southeastern Sweden through the Baltic Sea to Lithuania. This is a contribution to the Open Access Centre activities Mansfeld, J., Beunk, F.F. and Barling, J., 2005. GFF, 127: 149-157 Makowsky, F., Mansfeld, J., 2013. 31st Nordic Geological Winter Meeting, Lund, Sweden, 89-90.

Geology for youth in Lithuania: International Year of Planet Earth-related and other activities

NASA Astrophysics Data System (ADS)

Skridlaite, Grazina; Guobyte, Rimante; Skrinskas, Skirmantas; Nemaniene, Jurgita

2010-05-01

A great number of Lithuanian secondary and high schools devoted a range of activities to Earth sciences on September 22 (autumn equinox), 2008 proclaimed by the Lithuanian National Committee for IYPE and Ministry of Education and Science of Lithuania as "Earth's day". Beforehand, the 11 IYPE brochures were translated, supplemented with relevant Lithuanian data and placed on the website www.zemesmetai.lt. The activities comprised lessons, competitions, performances, field trips, seminars, excursions to museums and nature sites, meetings with geologists and naturalists etc. In many schools the 10 scientific themes were expanded, transformed and included into different school programmes such as geography, chemistry, physics, biology, Lithuanian language etc. The other schools preferred to organise discussions, performances and concerts where children expressed their concern about future of the Earth and suggested ways to save it. Several schools invited geologists, ecologists or other representatives of Earth sciences or local authorities to provide with information on environmental and geological issues in Lithuania and their own surroundings. Several museums and nature sites were visited. The "Earth's day" was advertised and broadcasted on TV and radio, reflected in the press. The reports from schools were placed on the Lithuanian IYPE website. The Board acknowledged the best participants with special letter of thanks. It turned out that despite the provided information on different subjects of geology only few of them were chosen. School teachers encountered some problems relating the Earth's interior with its surface, recognising modern geological processes etc. They found some brochures to be too complicated for non-specialists. Biodiversity was much easier to explain and present as geodiversity. Nevertheless, everybody admitted the great importance of geosciences in society and insufficient knowledge, and greatly acknowledged the initiative of the IYPE. The "Earth's day" initiative triggered a lot of activities and joint projects at Lithuanian schools and public institutions devoted to Earth sciences. Many geologists and other scientists were invited to schools, public and governmental institutions to provide with all sorts of geological information. A lot of different competitions, camps and seminars followed the "Earth's day". As a special success the Young Geologist movement hosted by the NGO Lithuanian Youth Tourism Center has to be admitted. Summer camps, seminars, competitions on geology have been organized at the Center for more than 25 years. The successful co-operation with the Ministry of Education and Science of Lithuania and also with several private and governmental institutions and commercial enterprises resulted in a publishing of a special calendar for 2009. Each month in the calendar is devoted to the institution or enterprise either related to geosciences, using nature resources in a sustainable way or producing environmentally friendly goods or energy. The calendar was distributed to Lithuanian schools, public and governmental institutions. Inspired by the success of the "Earth's day", the LitNC and Ministry of Education and Science organised a competition "Earth in our hands" for all types of schools in 2009. Over 50 PowerPoint presentations, movies, drawings, photos and posters were received at the Center of Young Naturalists in Vilnius. The winners were awarded with a special "geotour" on September 25.

U.S. Foreign Policy Towards Latvia During the Inter-War Period, 1917- 1941

DTIC Science & Technology

1993-04-01

Latvia. and Lithuania in Lhe Twentieth Century. New York: Longman, 1991. Hixson, Walter L. George F. Kennan: Cold War Iconoclast . New York: Columbia...Walter L. George F. Kennan: Cold War Iconoclast . New York: Columbia University Press, 1989. Hodgson, Godfrey. The Colonel: The Life and Wars of...Cold War Iconoclast (New York: Columbia University Press, 1989), 7. 64 The Russian Section furnished the State Department with considerable evidence that

Annual Threat Assessment of the US Intelligence Community for the House Permanent Select Committee on Intelligence

DTIC Science & Technology

2010-02-03

water and power shortages, and a major currency devaluation , raising questions about his longer term political future. On foreign policy, Chavez’s...have not disappeared. Most emerging market nations have weathered the crisis, international private investment flows are recovering, and the IMF has...lose support from the IMF and other sources of finance. Bulgaria, Estonia, Greece, Hungary, Iceland, Ireland, Latvia, Lithuania, and Romania remain

JPRS Report, Soviet Union, Military Affairs

DTIC Science & Technology

1990-05-09

these years and we are not very rich but I understand there would not be much in Lithuania if the republics did not help one another. Can we really...in avoiding the draft by his girlfriend I. Vasyagina, a nurse at the Cherepovets Metallurgical Combine trauma sta- tion. The law clearly...to schools, and enterprises to units. Sponsorship traditions are rich , and the Komsomol must have more than the last word to say here. Basic

Revisiting Transitions in the Arab World, Spring or Fall?

DTIC Science & Technology

2012-01-01

Further, how might democracy arrive, embed, and survive in Middle  Eastern Arab states? Conversely, might the passions for accountable  gover - nance...ment “Democracy  [is]  preferable  to other  forms of  government.”4 These results mirror other findings of widespread support for accountable gover ...Lithuania, and Ukraine. After years of turbulent democratic gover - nance, individuals preferring democracy to a strong leader fell from 51 to 29

Dissent and Nationalism in the Soviet Baltic.

DTIC Science & Technology

1983-09-01

and which, in the final analysis, also has an internal policing function, is manned on the principle of extraterri- toriality, which means that local...descriptor of current antiestablish- ment activities and attitudes in the Baltic region. The common mean - ing of "dissent," i.e., deviation by a minority...denied any means of support. The regime’s intentions to eradicate the Catholic religion in Lithuania were unmistakable. Despite the critical situation in

VizieR Online Data Catalog: Vilnius photometry of M29 (NGC6913) (Milasius+, 2013)

NASA Astrophysics Data System (ADS)

Milasius, K.; Boyle, R. P.; Vrba, F. J.; Janusz, R.; Straizys, V.; Cernis, K.; Laugalys, V.; Zdanavicius, K.; Zdanavicius, J.; Kazlauskas, A.; Smilgys, R.

2015-01-01

The observational material was obtained with CCD cameras on three different telescopes: the wide-field Maksutov-type 35/51cm telescope of the Moletai Observatory in Lithuania (2004), the 1m Ritchey telescope at the Flagstaff Station of the US Naval Observatory in Arizona (2006-2008) and the 1.8m VATT telescope of the Vatican Observatory on Mt. Graham, Arizona (2011-2012). (3 data files).

The Future of Transatlantic Security Relations. Colloquium Report

DTIC Science & Technology

2006-09-01

Black Sea region could be either active or reserve troops, and that Romania and Bulgaria were likely candidates for hosting the troops. The deployed...Bulgaria, Estonia, Latvia, Lithuania, Romania , Slovakia, and Slovenia. NATO now has 26 members. Nor is this all. Since the 1990s, the Alliance has...splendid isolation. • The World War I alliance that vanquished Imperial Germany in 1918 was defunct 1 year later, when the United States absconded

Genome-wide meta-analysis of SNP-by9-ACEI/ARB and SNP-by-thiazide diuretic and effect on serum potassium in cohorts of European and African ancestry.

PubMed

Irvin, Marguerite R; Sitlani, Colleen M; Noordam, Raymond; Avery, Christie L; Bis, Joshua C; Floyd, James S; Li, Jin; Limdi, Nita A; Srinivasasainagendra, Vinodh; Stewart, James; de Mutsert, Renée; Mook-Kanamori, Dennis O; Lipovich, Leonard; Kleinbrink, Erica L; Smith, Albert; Bartz, Traci M; Whitsel, Eric A; Uitterlinden, Andre G; Wiggins, Kerri L; Wilson, James G; Zhi, Degui; Stricker, Bruno H; Rotter, Jerome I; Arnett, Donna K; Psaty, Bruce M; Lange, Leslie A

2018-06-01

We evaluated interactions of SNP-by-ACE-I/ARB and SNP-by-TD on serum potassium (K+) among users of antihypertensive treatments (anti-HTN). Our study included seven European-ancestry (EA) (N = 4835) and four African-ancestry (AA) cohorts (N = 2016). We performed race-stratified, fixed-effect, inverse-variance-weighted meta-analyses of 2.5 million SNP-by-drug interaction estimates; race-combined meta-analysis; and trans-ethnic fine-mapping. Among EAs, we identified 11 significant SNPs (P < 5 × 10 -8 ) for SNP-ACE-I/ARB interactions on serum K+ that were located between NR2F1-AS1 and ARRDC3-AS1 on chromosome 5 (top SNP rs6878413 P = 1.7 × 10 -8 ; ratio of serum K+ in ACE-I/ARB exposed compared to unexposed is 1.0476, 1.0280, 1.0088 for the TT, AT, and AA genotypes, respectively). Trans-ethnic fine mapping identified the same group of SNPs on chromosome 5 as genome-wide significant for the ACE-I/ARB analysis. In conclusion, SNP-by-ACE-I /ARB interaction analyses uncovered loci that, if replicated, could have future implications for the prevention of arrhythmias due to anti-HTN treatment-related hyperkalemia. Before these loci can be identified as clinically relevant, future validation studies of equal or greater size in comparison to our discovery effort are needed.

Travel patterns of cancer surgery patients in a regionalized system.

PubMed

Smith, Andrew K; Shara, Nawar M; Zeymo, Alexander; Harris, Katherine; Estes, Randy; Johnson, Lynt B; Al-Refaie, Waddah B

2015-11-01

Regionalization of complex surgeries has increased patient travel distances possibly leaving a substantial burden on those at risk for poorer surgical outcomes. To date, little is known about travel patterns of cancer surgery patients in regionalized settings. To inform this issue, we sought to assess travel patterns of those undergoing a major cancer surgery within a regionalized system. We identified 4733 patients who underwent lung, esophageal, gastric, liver, pancreatic, and colorectal resections from 2002-2014 within a multihospital system in the Mid-Atlantic region of the United States. Patient age, race and/or ethnicity, and insurance status were extracted from electronic health records. We used Geographical Information System capabilities in R software to estimate travel distance and map patient addresses based on cancer surgery type and these characteristics. We used visual inspection, analysis of variance, and interaction analyses to assess the distribution of travel distances between patient populations. A total of 48.2% of patients were non-white, 49.9% were aged >65 y, and 54.9% had private insurance. Increased travel distance was associated with decreasing age and those undergoing pancreatic and esophageal resections. Also, black patients tend to travel shorter distances than other racial and/or ethnic groups. These maps offer a preliminary understanding into variations of geospatial travel patterns among patients receiving major cancer surgery in a Mid-Atlantic regionalized setting. Future research should focus on the impact of regionalization on timely delivery of surgical care and other quality metrics. Copyright © 2015 Elsevier Inc. All rights reserved.

Two sources of the Russian patrilineal heritage in their Eurasian context.

PubMed

Balanovsky, Oleg; Rootsi, Siiri; Pshenichnov, Andrey; Kivisild, Toomas; Churnosov, Michail; Evseeva, Irina; Pocheshkhova, Elvira; Boldyreva, Margarita; Yankovsky, Nikolay; Balanovska, Elena; Villems, Richard

2008-01-01

Progress in the mapping of population genetic substructure provides a core source of data for the reconstruction of the demographic history of our species and for the discovery of common signals relevant to disease research: These two aspects of enquiry overlap in their empirical data content and are especially informative at continental and subcontinental levels. In the present study of the variation of the Y chromosome pool of ethnic Russians, we show that the patrilineages within the pre-Ivan the Terrible historic borders of Russia have two main distinct sources. One of these antedates the linguistic split between West and East Slavonic-speaking people and is common for the two groups; the other is genetically highlighted by the pre-eminence of haplogroup (hg) N3 and is most parsimoniously explained by extensive assimilation of (or language change in) northeastern indigenous Finno-Ugric tribes. Although hg N3 is common for both East European and Siberian Y chromosomes, other typically Siberian or Mongolian hgs (Q and C) have negligible influence within the studied Russian Y chromosome pool. The distribution of all frequent Y chromosome haplogroups (which account for 95% of the Y chromosomal spectrum in Russians) follows a similar north-south clinal pattern among autosomal markers, apparent from synthetic maps. Multidimensional scaling (MDS) plots comparing intra ethnic and interethnic variation of Y chromosome in Europe show that although well detectable, intraethnic variation signals do not cross interethnic borders, except between Poles, Ukrainians, and central-southern Russians, thereby revealing their overwhelmingly shared patrilineal ancestry.

Analysis of personal and cultural values as key determinants of novel food acceptance. Application to an ethnic product.

PubMed

Barrena, Ramo; García, Teresa; Sánchez, Mercedes

2015-04-01

This paper sets out to analyse whether the complexity and the type of benefits and values pursued in the consumer choice process for a novel food product (couscous) varies with the consumer's ethnic origin (Spanish and Arab). A qualitative study was used to explore these issues in an application of the "means-end chain" theory. The hierarchical value maps obtained point to the presence of an important emotional dimension in the consumption of the selected product, particularly Arab consumers, suggesting that greater familiarity with the product results in a more complex choice process. Some cross-cultural variation can also be observed. Arab consumers attach more importance to issues such as the geographic origin of the product, cultural identification, and fulfilment of family duty. Spanish couscous consumers, meanwhile, claim that it is a way to follow the latest trends, and be more cosmopolitan and more successful within their environment. Copyright © 2014 Elsevier Ltd. All rights reserved.

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

PubMed Central

Huang, Hailiang; Ng, Siew C; Alberts, Rudi; Takahashi, Atsushi; Ripke, Stephan; Lee, James C; Jostins, Luke; Shah, Tejas; Abedian, Shifteh; Cheon, Jae Hee; Cho, Judy; Dayani, Naser E; Franke, Lude; Fuyuno, Yuta; Hart, Ailsa; Juyal, Ramesh C; Juyal, Garima; Kim, Won Ho; Morris, Andrew P; Poustchi, Hossein; Newman, William G; Midha, Vandana; Orchard, Timothy R; Vahedi, Homayon; Sood, Ajit; Sung, Joseph Y; Malekzadeh, Reza; Westra, Harm-Jan; Yamazaki, Keiko; Yang, Suk-Kyun; Barrett, Jeffrey C; Alizadeh, Behrooz Z; Parkes, Miles; BK, Thelma; Daly, Mark J; Kubo, Michiaki; Anderson, Carl A; Weersma, Rinse K

2016-01-01

Ulcerative colitis and Crohn’s disease are the two main forms of inflammatory bowel disease (IBD). Here, we report the first trans-ethnic association study of IBD, with genome-wide or Immunochip genotype data from an extended cohort of 86,640 European individuals and Immunochip data from 9,846 individuals of East-Asian, Indian or Iranian descent. We implicate 38 loci in IBD risk for the first time. For the majority of IBD risk loci, the direction and magnitude of effect is consistent in European and non-European cohorts. Nevertheless, we observe genetic heterogeneity between divergent populations at several established risk loci driven by a combination of differences in allele frequencies (NOD2), effect sizes (TNFSF15, ATG16L1) or a combination of both (IL23R, IRGM). Our results provide biological insights into the pathogenesis of IBD, and demonstrate the utility of trans-ethnic association studies for mapping complex disease loci and understanding genetic architecture across diverse populations. PMID:26192919

Transancestral mapping and genetic load in systemic lupus erythematosus.

PubMed

Langefeld, Carl D; Ainsworth, Hannah C; Cunninghame Graham, Deborah S; Kelly, Jennifer A; Comeau, Mary E; Marion, Miranda C; Howard, Timothy D; Ramos, Paula S; Croker, Jennifer A; Morris, David L; Sandling, Johanna K; Almlöf, Jonas Carlsson; Acevedo-Vásquez, Eduardo M; Alarcón, Graciela S; Babini, Alejandra M; Baca, Vicente; Bengtsson, Anders A; Berbotto, Guillermo A; Bijl, Marc; Brown, Elizabeth E; Brunner, Hermine I; Cardiel, Mario H; Catoggio, Luis; Cervera, Ricard; Cucho-Venegas, Jorge M; Dahlqvist, Solbritt Rantapää; D'Alfonso, Sandra; Da Silva, Berta Martins; de la Rúa Figueroa, Iñigo; Doria, Andrea; Edberg, Jeffrey C; Endreffy, Emőke; Esquivel-Valerio, Jorge A; Fortin, Paul R; Freedman, Barry I; Frostegård, Johan; García, Mercedes A; de la Torre, Ignacio García; Gilkeson, Gary S; Gladman, Dafna D; Gunnarsson, Iva; Guthridge, Joel M; Huggins, Jennifer L; James, Judith A; Kallenberg, Cees G M; Kamen, Diane L; Karp, David R; Kaufman, Kenneth M; Kottyan, Leah C; Kovács, László; Laustrup, Helle; Lauwerys, Bernard R; Li, Quan-Zhen; Maradiaga-Ceceña, Marco A; Martín, Javier; McCune, Joseph M; McWilliams, David R; Merrill, Joan T; Miranda, Pedro; Moctezuma, José F; Nath, Swapan K; Niewold, Timothy B; Orozco, Lorena; Ortego-Centeno, Norberto; Petri, Michelle; Pineau, Christian A; Pons-Estel, Bernardo A; Pope, Janet; Raj, Prithvi; Ramsey-Goldman, Rosalind; Reveille, John D; Russell, Laurie P; Sabio, José M; Aguilar-Salinas, Carlos A; Scherbarth, Hugo R; Scorza, Raffaella; Seldin, Michael F; Sjöwall, Christopher; Svenungsson, Elisabet; Thompson, Susan D; Toloza, Sergio M A; Truedsson, Lennart; Tusié-Luna, Teresa; Vasconcelos, Carlos; Vilá, Luis M; Wallace, Daniel J; Weisman, Michael H; Wither, Joan E; Bhangale, Tushar; Oksenberg, Jorge R; Rioux, John D; Gregersen, Peter K; Syvänen, Ann-Christine; Rönnblom, Lars; Criswell, Lindsey A; Jacob, Chaim O; Sivils, Kathy L; Tsao, Betty P; Schanberg, Laura E; Behrens, Timothy W; Silverman, Earl D; Alarcón-Riquelme, Marta E; Kimberly, Robert P; Harley, John B; Wakeland, Edward K; Graham, Robert R; Gaffney, Patrick M; Vyse, Timothy J

2017-07-17

Systemic lupus erythematosus (SLE) is an autoimmune disease with marked gender and ethnic disparities. We report a large transancestral association study of SLE using Immunochip genotype data from 27,574 individuals of European (EA), African (AA) and Hispanic Amerindian (HA) ancestry. We identify 58 distinct non-HLA regions in EA, 9 in AA and 16 in HA (∼50% of these regions have multiple independent associations); these include 24 novel SLE regions (P<5 × 10 -8 ), refined association signals in established regions, extended associations to additional ancestries, and a disentangled complex HLA multigenic effect. The risk allele count (genetic load) exhibits an accelerating pattern of SLE risk, leading us to posit a cumulative hit hypothesis for autoimmune disease. Comparing results across the three ancestries identifies both ancestry-dependent and ancestry-independent contributions to SLE risk. Our results are consistent with the unique and complex histories of the populations sampled, and collectively help clarify the genetic architecture and ethnic disparities in SLE.

Transancestral mapping and genetic load in systemic lupus erythematosus

PubMed Central

Langefeld, Carl D.; Ainsworth, Hannah C.; Graham, Deborah S. Cunninghame; Kelly, Jennifer A.; Comeau, Mary E.; Marion, Miranda C.; Howard, Timothy D.; Ramos, Paula S.; Croker, Jennifer A.; Morris, David L.; Sandling, Johanna K.; Almlöf, Jonas Carlsson; Acevedo-Vásquez, Eduardo M.; Alarcón, Graciela S.; Babini, Alejandra M.; Baca, Vicente; Bengtsson, Anders A.; Berbotto, Guillermo A.; Bijl, Marc; Brown, Elizabeth E.; Brunner, Hermine I.; Cardiel, Mario H.; Catoggio, Luis; Cervera, Ricard; Cucho-Venegas, Jorge M.; Dahlqvist, Solbritt Rantapää; D’Alfonso, Sandra; Da Silva, Berta Martins; de la Rúa Figueroa, Iñigo; Doria, Andrea; Edberg, Jeffrey C.; Endreffy, Emőke; Esquivel-Valerio, Jorge A.; Fortin, Paul R.; Freedman, Barry I.; Frostegård, Johan; García, Mercedes A.; de la Torre, Ignacio García; Gilkeson, Gary S.; Gladman, Dafna D.; Gunnarsson, Iva; Guthridge, Joel M.; Huggins, Jennifer L.; James, Judith A.; Kallenberg, Cees G. M.; Kamen, Diane L.; Karp, David R.; Kaufman, Kenneth M.; Kottyan, Leah C.; Kovács, László; Laustrup, Helle; Lauwerys, Bernard R.; Li, Quan-Zhen; Maradiaga-Ceceña, Marco A.; Martín, Javier; McCune, Joseph M.; McWilliams, David R.; Merrill, Joan T.; Miranda, Pedro; Moctezuma, José F.; Nath, Swapan K.; Niewold, Timothy B.; Orozco, Lorena; Ortego-Centeno, Norberto; Petri, Michelle; Pineau, Christian A.; Pons-Estel, Bernardo A.; Pope, Janet; Raj, Prithvi; Ramsey-Goldman, Rosalind; Reveille, John D.; Russell, Laurie P.; Sabio, José M.; Aguilar-Salinas, Carlos A.; Scherbarth, Hugo R.; Scorza, Raffaella; Seldin, Michael F.; Sjöwall, Christopher; Svenungsson, Elisabet; Thompson, Susan D.; Toloza, Sergio M. A.; Truedsson, Lennart; Tusié-Luna, Teresa; Vasconcelos, Carlos; Vilá, Luis M.; Wallace, Daniel J.; Weisman, Michael H.; Wither, Joan E.; Bhangale, Tushar; Oksenberg, Jorge R.; Rioux, John D.; Gregersen, Peter K.; Syvänen, Ann-Christine; Rönnblom, Lars; Criswell, Lindsey A.; Jacob, Chaim O.; Sivils, Kathy L.; Tsao, Betty P.; Schanberg, Laura E.; Behrens, Timothy W.; Silverman, Earl D.; Alarcón-Riquelme, Marta E.; Kimberly, Robert P.; Harley, John B.; Wakeland, Edward K.; Graham, Robert R.; Gaffney, Patrick M.; Vyse, Timothy J.

2017-01-01

Systemic lupus erythematosus (SLE) is an autoimmune disease with marked gender and ethnic disparities. We report a large transancestral association study of SLE using Immunochip genotype data from 27,574 individuals of European (EA), African (AA) and Hispanic Amerindian (HA) ancestry. We identify 58 distinct non-HLA regions in EA, 9 in AA and 16 in HA (∼50% of these regions have multiple independent associations); these include 24 novel SLE regions (P<5 × 10−8), refined association signals in established regions, extended associations to additional ancestries, and a disentangled complex HLA multigenic effect. The risk allele count (genetic load) exhibits an accelerating pattern of SLE risk, leading us to posit a cumulative hit hypothesis for autoimmune disease. Comparing results across the three ancestries identifies both ancestry-dependent and ancestry-independent contributions to SLE risk. Our results are consistent with the unique and complex histories of the populations sampled, and collectively help clarify the genetic architecture and ethnic disparities in SLE. PMID:28714469

Fire impacts on European Boreal soils: A review

NASA Astrophysics Data System (ADS)

Pereira, Paulo; Oliva, Marc; Cerda, Artemi

2016-04-01

Fire is an important natural disturbance in boreal ecosystems, fundamental to understand plant distribution (Ryan, 2002; Wallenius et al., 2004; Granstrom, 2001). Nevertheless, nowadays the intense and successful, fire suppression measures are changing their ecological role (Pereira et al., 2013a,b). This is consequence of the lack of understanding of stakeholders and decision makers about the role of the fire in the ecosystems (Mierasukas and Pereira, 2013; Pereira et al., 2016). This fire suppression measures are increasing the amount of fuel accumulation and the risk of severe wildfires, which can increase of frequency and severity in a context of climate change. Fire is a good tool for landscape management and restoration of degraded ecosystems (Toivanen and Kotiaho, 2007). Fire is considered a soil forming factor (Certini, 2014) and in boreal environments it has been observed that low fire severities, do not change importantly soil properties, mean fire severities induce positive impacts on soil, since add an important amounts of nutrients into soil profile and high severity fires had negative impacts due to the high consumption of organic matter (Vanha-Majamaa et al., 2007; Pereira et al., 2014). References Certini, G., 2014. Fire as a soil-forming factor. Ambio, 43, 191-195 Granstrom A. 2001. Fire management for biodiversity in the European Boreal forest. Scandinavian Journal of Forest Research 3: 62-69. Mierauskas, P., Pereira, P. (2013) Stakeholders perception about prescribed fire use in Lithuania. First results, Flamma, 4(3), 157-161. Pereira, P., Cerdà, A., Jordán, A., Bolutiene, V., Úbeda, X., Pranskevicius, M., Mataix-Solera, J. (2013) Spatio-temporal vegetation recuperation after a grassland fire in Lithuania, Procedia Environmental Sciences, 19:856-864 Pereira, P., Mierauskas, P., Ubeda, X., Mataix-Solera, J.,Cerda, A. (2012) Fire in protected areas - the effect of the protection and importance of fire management, Environmental Research, Engineering and Management, 1(59), 52-62. Pereira, P., Ubeda, X., Mataix-Solera, J., Oliva, M., Novara, A. (2014) Short-term spatio-temporal spring grassland fire effects on soil colour,organic matter and water repellency in Lithuania, Solid Earth, 5, 209-225. Ryan KC. 2002. Dynamic Interactions between forest structure and fire behavioural in boreal ecosystems. Silva Fennica 36: 13-39 Toivanen T, Kotiaho JS. 2007. Mimicking natural disturbances of boreal forests: the effects of controlled burning and creating dead wood on beetle diversity. Biodiversity Conservation 16: 3193-3211.

Pharmacogenetics.

PubMed

Roses, A D

2001-10-01

Pharmacogenetics is the variability of drug response due to inherited characteristics in individuals. Drug metabolizing enzymes have been studied for decades, first as chemical reactions and, more recently, as specific polymorphisms of known molecules. With the availability of whole-genome single-nucleotide polymorphism (SNP) maps, it will soon be possible to create an SNP profile for patients who experience adverse events (AEs) or who respond clinically to the medicine (efficacy). Proof-of-principle experiments have demonstrated that high density SNP maps in chromosomal regions of genetic linkage facilitate the identification of susceptibility disease genes. Whole-genome SNP mapping analyses aimed at determining linkage disequilibrium (LD) profiles along an ordered human genome backbone are in progress. SNP 'fingerprints' or SNP PRINTs(sm) will be used to identify patients at greater risk of an AE, or those patients with a greater chance of responding to a medicine. As LD maps for various ethnic populations are constructed, the number of SNPs necessary to measure for an individual will decrease. Standardized pharmacogenetic maps for drug registration and post-marketing surveillance will result in safer, more effective and more cost-efficient medicines. The timing of these pharmacogenetic applications will occur over the next 5 years. In contrast, the benefits of pharmacogenomic applications such as the identification of new tractable targets will not be visible as new medicines for 7-12 years, due to the lengthy drug development and registration processes.

Genetic ancestry is associated with subclinical cardiovascular disease in African Americans and Hispanics from the Multi-Ethnic Study of Atherosclerosis (MESA)

PubMed Central

Wassel, Christina L.; Pankow, James S.; Peralta, Carmen A.; Choudhry, Shweta; Seldin, Michael F.; Arnett, Donna K.

2009-01-01

Background Differences in cardiovascular disease (CVD) burden exist among racial/ethnic groups in the United States, with African Americans having the highest prevalence. Subclinical CVD measures have also been shown to differ by race/ethnicity. In the United States, there has been significant intermixing among racial/ethnic groups creating admixed populations. Very little research exists on the relationship of genetic ancestry and subclinical CVD measures. Methods and Results These associations were investigated in 712 African-American and 705 Hispanic participants from the MESA candidate gene sub-study. Individual ancestry was estimated from 199 genetic markers using STRUCTURE. Associations of ancestry and coronary artery calcium (CAC) and common and internal carotid intima media thickness (cIMT) were evaluated using log-binomial and linear regression models. Splines indicated linear associations of ancestry with subclinical CVD measures in African-Americans, but presence of threshold effects in Hispanics. Among African Americans, each standard deviation (SD) increase in European ancestry was associated with an 8% (95% CI (1.02, 1.15), p=0.01) greater CAC prevalence. Each SD increase in European ancestry was also associated with a 2% (95% CI (−3.4%, −0.5%), p=0.008) lower common cIMT in African Americans. Among Hispanics, the highest tertile of European ancestry was associated with a 34% greater CAC prevalence, p=0.02 as compared to lowest tertile. Conclusions The linear association of ancestry and subclinical CVD suggests that genetic effects may be important in determining CAC and cIMT among African-Americans. Our results also suggest that CAC and common cIMT may be important phenotypes for further study with admixture mapping. PMID:20031644

Trans-ethnic fine mapping identifies a novel independent locus at the 3' end of CDKAL1 and novel variants of several susceptibility loci for type 2 diabetes in a Han Chinese population.

PubMed

Kuo, Jane Z; Sheu, Wayne Huey-Herng; Assimes, Themistocles L; Hung, Yi-Jen; Absher, Devin; Chiu, Yen-Feng; Mak, Jordan; Wang, Jun-Sing; Kwon, Soonil; Hsu, Chih-Cheng; Goodarzi, Mark O; Lee, I-Te; Knowles, Joshua W; Miller, Brittany E; Lee, Wen-Jane; Juang, Jyh-Ming J; Wang, Tzung-Dau; Guo, Xiuqing; Taylor, Kent D; Chuang, Lee-Ming; Hsiung, Chao A; Quertermous, Thomas; Rotter, Jerome I; Chen, Yii-Der I

2013-12-01

Candidate gene and genome-wide association studies have identified ∼60 susceptibility loci for type 2 diabetes. A majority of these loci have been discovered and tested only in European populations. The aim of this study was to assess the presence and extent of trans-ethnic effects of these loci in an East Asian population. A total of 9,335 unrelated Chinese Han individuals, including 4,535 with type 2 diabetes and 4,800 non-diabetic ethnically matched controls, were genotyped using the Illumina 200K Metabochip. We tested 50 established loci for type 2 diabetes and related traits (fasting glucose, fasting insulin, 2 h glucose). Disease association with the additive model of inheritance was analysed with logistic regression. We found that 14 loci significantly transferred to the Chinese population, with two loci (p = 5.7 × 10(-12) for KCNQ1; p = 5.0 × 10(-8) for CDKN2A/B-CDKN2BAS) reaching independent genome-wide statistical significance. Five of these 14 loci had similar lead single-nucleotide polymorphisms (SNPs) as were found in the European studies while the other nine were different. Further stepwise conditional analysis identified a total of seven secondary signals and an independent novel locus at the 3' end of CDKAL1. These results suggest that many loci associated with type 2 diabetes are commonly shared between European and Chinese populations. Identification of population-specific SNPs may increase our understanding of the genetic architecture underlying type 2 diabetes in different ethnic populations.

Engaging the Somali community in the road safety agenda: a process evaluation from the London borough of Hounslow.

PubMed

Christie, Nicola; Sleney, Judith; Ahmed, Fatima; Knight, Elisabeth

2012-08-01

In the UK the most disadvantaged in society are more likely than those more affluent to be injured or killed in a road traffic collision and therefore it is a major cause of health inequality. There is a strong link between ethnicity, deprivation and injury. Whilst national road traffic injury data does not collect ethnic origin the London accident and analysis group does in terms of broad categories such as 'white', 'black' and 'Asian'. Analysis of this data revealed the over-representation of child pedestrian casualties from a 'black' ethnic origin. This information led road safety practitioners in one London borough to map child pedestrian casualties against census data which identified the Somali community as being particularly at risk of being involved in a road traffic collision. Working with the community they sought to discuss and address road safety issues and introduced practical evidence based approaches such as child pedestrian training. The process evaluation of the project used a qualitative approach and showed that engaging with community partners and working across organisational boundaries was a useful strategy to gain an understanding of the Somali community. A bottom approach provided the community with a sense of control and involvement which appears to add value in terms of reducing the sense of powerlessness that marginalised communities often feel. In terms of evaluation, small projects like these, lend themselves to a qualitative process evaluation though it has to be accepted that the strength of this evidence may be regarded as weak. Where possible routine injury data needs to take into account ethnicity which is a known risk factor for road casualty involvement which needs to be continually monitored.

Common genetic variants and subclinical atherosclerosis: The Multi-Ethnic Study of Atherosclerosis (MESA).

PubMed

Vargas, Jose D; Manichaikul, Ani; Wang, Xin-Qun; Rich, Stephen S; Rotter, Jerome I; Post, Wendy S; Polak, Joseph F; Budoff, Matthew J; Bluemke, David A

2016-02-01

Subclinical atherosclerosis (sCVD), measured by coronary artery calcium (CAC) and carotid intima media thickness (CIMT) is associated with cardiovascular disease (CVD). Genome-Wide Association Studies (GWAS) of sCVD and CVD have focused primarily on Caucasian populations. We hypothesized that these associations may differ in populations from distinct genetic backgrounds. The associations between sCVD and 66 single nucleotide polymorphisms (SNPs) from published GWAS of sCVD and CVD were tested in 8224 Multi-Ethnic Study of Atherosclerosis (MESA) and MESA Family participants [2329 Caucasians (EUA), 691 Chinese (CHN), 2482 African Americans (AFA), and 2012 Hispanic (HIS)] using an additive model adjusting for CVD risk factors, with SNP significance defined by a Bonferroni-corrected p < 7.6 × 10(-4) (0.05/66). In EUA there were significant associations for CAC with SNPs in 9p21 (rs1333049, P = 2 × 10(-9); rs4977574, P = 4 × 10(-9)), COL4A1 (rs9515203, P = 9 × 10(-6)), and PHACTR1 (rs9349379, P = 4 × 10(-4)). In HIS, CAC was associated with SNPs in 9p21 (rs1333049, P = 8 × 10(-5); rs4977574, P = 5 × 10(-5)), APOA5 (rs964184, P = 2 × 10(-4)), and ADAMTS7 (rs7173743, P = 4 × 10(-4)). There were no associations between CAC and 9p21 SNPs for AFA and CHN. Fine mapping of the 9p21 region revealed SNPs with robust associations with CAC in EUA and HIS but no significant associations in AFA and CHN. Our results suggest some shared genetic architecture for sCVD across ethnic groups, while also underscoring the possibility of novel variants and/or pathways in risk of CVD in ethnically diverse populations. Published by Elsevier Ireland Ltd.

Ethnic, socioeconomic and geographical inequalities in road traffic injury rates in the Auckland region.

PubMed

Hosking, Jamie; Ameratunga, Shanthi; Exeter, Daniel; Stewart, Joanna; Bell, Andrew

2013-04-01

To describe ethnic, socioeconomic and geographical differences in road traffic injury (RTI) within Auckland, New Zealand's largest city. We analysed rates of RTI deaths and non-fatal hospital admissions using the New Zealand Mortality Collection and the National Minimum Data Set 2000-08. Poisson regression examined the association of age, gender, prioritised ethnicity and small area deprivation (New Zealand Index of Deprivation) with RTI rates, and RTI rates were mapped for 21 local board areas within the Auckland region. While RTI rates increased with levels of deprivation in all age groups, the gradient was steepest among children (9% increase/decile) and adults aged 25-64 years (11% increase/decile). In all age groups, RTI risk was highest among Māori. Pacific children had an elevated risk of RTI compared with the NZ European/Other group, but Pacific youth (15-24 years) and adults (25-64 years) had a lower risk. While RTI rates were generally higher for those living in rural local board areas, all but one local board in the southern Auckland urban area had among the highest rates. There are substantial ethnic, socioeconomic and geographic inequalities in RTI risk in the Auckland region, with high rates among Māori (all ages), Pacific children, people living in socioeconomically deprived neighbourhoods, the urban south and rural regions. To meet the vision of regional plans, road safety efforts must prioritise vulnerable communities at greatest risk of RTI, and implement and monitor the effectiveness of strategies that specifically include a focus on reducing inequalities in RTI rates. © 2013 The Authors. ANZJPH © 2013 Public Health Association of Australia.

Recapitulation of genome-wide association studies on body mass index in the Korean population.

PubMed

Hong, K W; Oh, B

2012-08-01

Obesity is a risk factor for multiple disorders such as diabetes and cardiovascular disease. Recently, a genome-wide association study for body mass index (BMI) was conducted in 249 796 individuals of European ancestry by the Genetic Investigation of Anthropometric Traits (GIANT) consortium. They identified 14 known obesity susceptibility loci and 18 new loci associated with BMI at the genome-wide significance level (P<5 × 10⁻⁸). Because the prevalence and severity of obesity vary among ethnic groups, it is worthy to investigate these results in another ethnic population. We examined the BMI association of 19 single-nucleotide polymorphisms (SNPs) out of the 32 in 8842 individuals from the Korean Association Resource data, and found 12 SNPs to be associated with BMI in the Korean population. Eight loci, rs10968576 (BDNF), rs3817334 (MTCH2), rs1558902 (FTO), rs571312 (MC4R), rs543874 (SEC16B), rs987237 (TFAP2B), rs2867125 (TMEM18) and rs7138803 (FAIM2), were previously known obesity susceptibility loci, and the remaining four loci, rs1514175 (TNNI3K), rs206936 (NUDT3), rs4771122 (MTIF3) and rs2241423 (MAP2K5), were newly identified as BMI loci by the GIANT study. Further, all 12 SNPs showed the same direction of effect on BMI between the two ethnic groups, suggesting a similar genetic architecture governing the obesity.

Vitamin D receptor gene methylation is associated with ethnicity, tuberculosis and TaqI polymorphism

PubMed Central

Andraos, Charlene; Koorsen, Gerrit; Knight, Julian C; Bornman, Liza

2014-01-01

The Vitamin D Receptor (VDR) gene encodes a transcription factor which, on activation by vitamin D, modulates diverse biological processes including calcium homeostasis and immune function. Genetic variation involving VDR shows striking differences in allele frequency between populations and has been associated with disease susceptibility including tuberculosis and autoimmunity, although results have often been conflicting. We hypothesized that methylation of VDR may be population specific and that the combination of differential methylation and genetic variation may characterise TB predisposition. We use bisulphite conversion and/or pyrosequencing to analyse the methylation status of 17 CpGs of VDR and to genotype 7 SNPs in the 3′ CpG Island (CGI 1060), including the commonly studied SNPs ApaI (rs7975232) and TaqI (rs731236). We show that for lymphoblastoid cell lines from two ethnically diverse populations (Yoruba from HapMap, n=30 and Caucasians, n=30) together with TB cases (n=32) and controls (n=29) from the Venda population of South Africa there are methylation variable positions (MVPs) in the 3′ end that significantly distinguish ethnicity (9/17 CpGs) and TB status (3/17 CpGs). Moreover methylation status shows complex association with TaqI genotype highlighting the need to consider both genetic and epigenetic variants in genetic studies of VDR association with disease. PMID:21168462

Interethnic admixture and the evolution of Latin American populations

PubMed Central

Salzano, Francisco Mauro; Sans, Mónica

2014-01-01

A general introduction to the origins and history of Latin American populations is followed by a systematic review of the data from molecular autosomal assessments of the ethnic/continental (European, African, Amerindian) ancestries for 24 Latin American countries or territories. The data surveyed are of varying quality but provide a general picture of the present constitution of these populations. A brief discussion about the applications of these results (admixture mapping) is also provided. Latin American populations can be viewed as natural experiments for the investigation of unique anthropological and epidemiological issues. PMID:24764751

Case Study: The Withdrawal of Russian Military Forces from the Baltic States

DTIC Science & Technology

1996-01-01

Llthuama, Latvia and Estoma regained the independence they had lost at the start of the Second World War The opportumty for these new states to...Russia was perceived as pursuing a pohcy of mtlmldatlon toward Latvia, Lithuania and Estoma As the Russia-Baltic dialogue began to deteriorate m 1993... Estoma Finally, Moscow needed good relations \\~th Vllnrus to ensure easy access to Kalmmgrad, the exclave on the Baltic Sea that was physically

Laboratories new to the ICRM.

PubMed

Karam, Lisa; Anagnostakis, Marios J; Gudelis, Arunas; Marsoem, Pujadi; Mauring, Alexander; Wurdiyanto, Gatot; Yücel, Ülkü

2012-09-01

The Scientific Committee of the ICRM decided, for the 2011 Conference, to present laboratories that are at a key developmental stage in establishing, expanding or applying radionuclide metrology capabilities. The expansion of radionuclide metrology capabilities is crucial to meet evolving and emerging needs in health care, environmental monitoring, and nuclear energy. Five laboratories (from Greece, Lithuania, Indonesia, Norway and Turkey) agreed to participate. Each laboratory is briefly introduced, and examples of their capabilities and standardization activities are discussed. Published by Elsevier Ltd.

Reinforcing Deterrence on NATO’s Eastern Flank: Wargaming the Defense of the Baltics

DTIC Science & Technology

2016-01-01

RUSSIA RUSSIA FINLAND POLAND LITHUANIA LATVIA ESTONIA BELARUS Vilnius Riga Helsinki Tallinn Minsk 6 ritorial integrity of the two countries. Under the best...them under Moscow’s nuclear umbrella. By turning a NATO counterattack aimed at liberating the Baltic republics into an “invasion” of “Russia...fires systems, in territory that even NATO would agree constitutes “Russia.” Under Russian doctrine, it is unclear what kinds or magnitudes of

The Security Concerns of the Baltic States as NATO Allies

DTIC Science & Technology

2013-08-01

Defence Col- lege in Tartu, Estonia, the military higher college of Estonia, Latvia, and Lithuania. Dr. Corum was a pro - fessor at the U.S. Army...Estonia, along with Finland , became the most modern, literate, and advanced regions of the Old Russian Empire. A cultural revival in the 19th...States were part of Europe designated as the Soviet sphere of influence, along with Eastern Poland and parts of Romania and Finland . The Soviet

United States Foreign Assistance Programs: The Requirement of Metrics for Security Assistance and Security Cooperation Programs

DTIC Science & Technology

2012-06-01

Czech Republic, Estonia, Hungary, Latvia, Lithuania, Poland, Romania , Slovakia, and Slovenia. 26 The seven PfP Eastern European countries, as...The Soviet experience has left an indelible mark in Ukrainian “identity, politics, economics and even religion ”127 and this experience looms large in...from Tsarist Russia to the Soviet Union from 1918 to 1921.186 The Russian and Soviet influences, along with previous Persian and Ottoman cultures

European Nationality Influence in the Management of Squamous Cell Vulvar Cancer.

PubMed

Iacoponi, Sara; Zapardiel, Ignacio

2017-01-01

Vulvar cancer is a rare disease. In western European countries, the incidence is 1.2 cases per 100,000 women/year. The aim of this study was to analyze the management and disease-free survival (DFS) of vulvar cancer among European countries. An international multicenter retrospective study including patients diagnosed of squamous cell vulvar cancer was performed. Countries analyzed included Austria, Germany, Greece, Italy, Latvia, Lithuania, Poland, Portugal, Spain and Turkey. One hundred different centers were enrolled including 1,505 squamous cell tumors treated from January 2001 until December 2005. The mean free surgical margin was 9.93 mm, which was different between countries (p = 0.076); it ranged from 5.79 mm (95% CI 4.44-7.13) in Germany to 33.39 mm (95% CI 22.21-44.58) in Lithuania. The global 5-year overall survival rate was 61.4%, and the global 5-year DFS rate was 32%. DFS times were different between countries as well as the treatments carried out. The country with the shortest DFS time had 15.9 ± 3.1 months compared to the one with the longest time with 66.0 ± 17.4 months. Wide differences in treatments and DFS times have been observed between countries. Homogeneous management for squamous cell vulvar cancer is needed to obtain the best survival rates for all patients. © 2016 S. Karger AG, Basel.

The self-reported quality of life of Lithuanian children with asthma was comparable to Western populations.

PubMed

Taminskiene, Vaida; Vaitkaitiene, Egle; Valiulis, Algirdas; Turner, Steve; Hadjipanayis, Adamos; Stukas, Rimantas; Valiulis, Arunas

2018-02-01

Quality of life (QoL) has been widely researched among children with asthma in Western countries, but there is a lack of data from eastern Europe, where the prevalence is relatively low, but hospital admission rates are higher. We evaluated the overall level and major determinants of QoL in Lithuanian children aged 5-11 years with asthma. This study was carried out in six asthma outpatient clinics in the two largest cities of Lithuania from January 2015 to July 2016. The children's QoL was measured using the Pediatric Quality of Life Inventory (PedsQL) asthma module, which was completed by the child and one parent. We collected questionnaires from 226 children (68% boys) with a mean age of eight (±2) years: 65% had mild asthma, 31% had moderate asthma and 4% had severe asthma. One in 10 had been hospitalised in the preceding 6 months. The mean self-reported QoL score was 74 and the parent-reported QoL score was 73. QoL was associated with asthma severity and control, shortness of breath and the child's general health, but not socioeconomic factors. The overall level and major determinants of QoL in children with asthma in Lithuania were comparable with Western populations. ©2017 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

Eye healthcare services in eastern Europe: Part 2. Vitreoretinal surgical services.

PubMed

Kocur, I; Resnikoff, S; Foster, A

2002-08-01

To describe vitreoretinal surgical services in 1998 in 12 eastern European countries and to identify ways for their further improvement. All inpatient eye departments in the 12 countries received a standardised questionnaire; the data obtained were processed at the international study coordinating centre in Prague. All 458 eye departments in the region were involved. The number of retinal detachments treated by extraocular surgery, or pars plana vitrectomy, per one million inhabitants respectively, were as follows: Belarus (52; 6), Federation of Bosnia and Herzegovina (21; 2), Bulgaria (39; 19), the Czech Republic (78; 40), Estonia (60; 17), Hungary (81; 88), Latvia (82; 36), Lithuania (68; 6), Trans-Dniester Region of Moldova (6; -), Poland (70; data not available), Romania (24; 25), and Slovakia (67; 55). The number of people per one retinal laser was assessed (in millions): Belarus (1.26), Federation of Bosnia and Herzegovina (2.23), Bulgaria (0.59), the Czech Republic (0.22), Estonia (0.24), Hungary (0.23), Latvia (0.41), Lithuania (0.62), Poland (0.36), Romania (2.25), and Slovakia (0.14). Conditions for posterior eye segment surgery in the central and eastern European region vary substantially. Underserved regions require (1) more eye doctors trained in surgical and laser retinal treatment; (2) improvement in screening for diabetic eye complications and retinopathy of prematurity; (3) technical equipment for places in need.

Eye healthcare services in eastern Europe: Part 1 Cataract surgery

PubMed Central

Kocur, I; Resnikoff, S; Foster, A

2002-01-01

Aim: To describe cataract surgical services in 1998 in 12 eastern European countries and to identify their needs to reduce cataract blindness. Methods: All inpatient eye departments in the 12 countries received a standardised questionnaire; the data obtained were further processed at the coordinating centre in Prague. Results: All 458 eye departments in the region were involved. The response rate was 100%, except for Bulgaria (93%) and Romania (93%). The total number of cataract surgeries per one million inhabitants in 1998 was calculated: Belarus (800), Federation of Bosnia and Herzegovina (1275), Bulgaria (1730), the Czech Republic (4210), Estonia (2530), Hungary (3530), Latvia (1860), Lithuania (1550), Trans-Dniester Moldova (1300), Poland (1475), Romania (1260), and Slovakia (2430). Cataracts were mostly operated on by the extracapsular technique. Intracapsular extractions were frequently performed in Federation of Bosnia and Herzegovina (47%), Belarus (46%), Bulgaria (18%), and Romania (14.3%). Phacoemulsification was uncommonly used in 1998, except for the Czech Republic (86%), Estonia (50%), Slovakia (38%), and Hungary (16%). An IOL was implanted in more than 90% of patients in the Czech Republic, Estonia, Hungary, Latvia, Lithuania, and Slovakia. Conclusions: Conditions for cataract surgery in the eastern European region differ. The main barriers to cataract surgery were state budget limitations, insufficient supply of consumables, underutilisation of operating theatres, and poor detection of patients requiring surgery. PMID:12140200

Eye healthcare services in eastern Europe: Part 2 Vitreoretinal surgical services

PubMed Central

Kocur, I; Resnikoff, S; Foster, A

2002-01-01

Aim: To describe vitreoretinal surgical services in 1998 in 12 eastern European countries and to identify ways for their further improvement. Methods: All inpatient eye departments in the 12 countries received a standardised questionnaire; the data obtained were processed at the international study coordinating centre in Prague. Results: All 458 eye departments in the region were involved. The number of retinal detachments treated by extraocular surgery, or pars plana vitrectomy, per one million inhabitants respectively, were as follows: Belarus (52; 6), Federation of Bosnia and Herzegovina (21; 2), Bulgaria (39; 19), the Czech Republic (78; 40), Estonia (60; 17), Hungary (81; 88), Latvia (82; 36), Lithuania (68; 6), Trans-Dniester Region of Moldova (6; –), Poland (70; data not available), Romania (24; 25), and Slovakia (67; 55). The number of people per one retinal laser was assessed (in millions): Belarus (1.26), Federation of Bosnia and Herzegovina (2.23), Bulgaria (0.59), the Czech Republic (0.22), Estonia (0.24), Hungary (0.23), Latvia (0.41), Lithuania (0.62), Poland (0.36), Romania (2.25), and Slovakia (0.14). Conclusions: Conditions for posterior eye segment surgery in the central and eastern European region vary substantially. Underserved regions require (1) more eye doctors trained in surgical and laser retinal treatment; (2) improvement in screening for diabetic eye complications and retinopathy of prematurity; (3) technical equipment for places in need. PMID:12140201

Cancer incidence among workers exposed to softwood dust in Lithuania.

PubMed

Smailyte, Giedre

2012-06-01

The aim of this study was to assess cancer incidence in a cohort of woodworkers exposed to softwood dust in a Lithuanian wooden joinery products factory. The study population consisted of 1518 workers (1080 men and 438 women) employed in the factory for at least 1 year between 1947 and 1996 and living in Lithuania on 1 January 1978, when the follow-up for cancer incidence began. The follow-up period for cancer was 1978-2007. Cancer risk was assessed by standardised incidence ratios (SIR) with reference to the national population. Overall cancer incidence was not increased among woodworkers. However, the number of mouth and pharynx cancer cases among male woodworkers was significantly increased compared with expected numbers (SIR 2.19, 95% CI 1.17 to 3.74). A higher risk was found for cancer of the buccal cavity than for pharyngeal cancer (SIRs 2.83 and 1.45, respectively). The SIR for larynx cancer was also elevated (SIR 1.39, 95% CI 0.64 to 2.64) among men, while the number of lung cancer cases was higher than expected only among women (SIR 2.07, 95% CI 00.57 to 5.31). This results of this study support the hypothesis that exposure to softwood dust may increase the risk of oral and pharyngeal cancer. No support was found for an increased risk of other respiratory cancers among workers exposed to softwood dust.

Stakeholder driven indicators for eHealth performance management.

PubMed

Vedlūga, Tomas; Mikulskienė, Birutė

2017-08-01

The goal of the present article is to compile a corpus of indicators of eHealth development evaluation that would essentially reflect stakeholder approaches and complement technical indicators of assessment of an eHealth system. Consequently, the assessment of the development of an eHealth system would reflect stakeholder approaches and become an innovative solution in attempting to improve productivity of IT projects in the field of health care. The compiled minimum set of indicators will be designed to monitor implementation of the national eHealth information system. To ensure reliability of the quality research, the respondents were grouped in accordance to the geographical distribution and diversity of the levels and types of the represented jobs and institutions. The applied analysis implies several managerial insights on the hierarchy of eHealth indicators. These insights may be helpful in recommending priority activities in implementation of an eHealth data system on the national or international level. The research is practically useful as it is the first to deal with the topic in Lithuania and its theoretical and practical aspect are particularly relevant in implementation of an eHealth data system in Lithuania. The eHealth assessment indicators presented in the article may be practically useful in two aspects: (1) as key implementation guidelines facilitating the general course of eHealth system development and (2) as a means to evaluate eHealth outcomes. Copyright © 2017 Elsevier Ltd. All rights reserved.

The Process of Creating Integrated Home Care in Lithuania: from Idea to Reality

PubMed Central

Jurkuvienė, Ramunė; Butkevičienė, Rūta; Gajdosikienė, Indrė

2016-01-01

Background: The article presents an analysis of the formulation and implementation of a social innovation: integrated home care (IHC) in post-soviet Lithuania. From 1998 a series of top-down orders to implement IHC were issued, however, home nursing did not start. In 2011 the Ministry of Social Security and Labour began a process to develop integrated home care using new, collaborative processes. The result was 21 pilot projects with well-conceptualized IHC services. Method: Using data from focus groups, interviews, and recorded observations, the research team systematically documented the innovation process, including themes and deviations, employing Smale’s Innovation Trinity framework to organize the larger picture. Results: In the Lithuanian post-totalitarian context, top-down communication was found to be prevalent. Not only IHC, but also openness to change and dialogue at high levels were innovations. Patient-centered practice at local levels could only occur when a new attitude of mind was reached through dialogue with officials at higher levels and between peers. Conclusions: The enactment, rather than the mask of dialogue, participatory program development were critical in the success of IHC innovation. This is difficult to achieve in the light of antiquated public bureaucracies, but in this case, the Ministry team, rather than avoiding the expectation of top-down communication, made it into an asset through promotion of collaboration. PMID:28435419

[A comparative study on characterizations of genetic recombination hotspots in PPARG gene between Kirgiz and Uyghur ethnic groups in Xinjiang].

PubMed

Zohra, Rozi; Song, M S; Iliham, Nizam; Dolikun, Mamatyusupu

2016-08-16

To investigate the characterizations of genetic recombination hotspots and linkage disequilibrium (LD) patterns in peroxisome proliferative activated receptor gamma (PPARG) gene in Kirgiz and Uyghur ethnic groups. Blood samples were collected from 100 Kirgiz (50 healthy controls and 50 patients with type 2 diabetes mellitus) residents in Halajun County, Artux City, Kizilsu Kirgiz Autonomous Prefecture, Xinjiang in August 2013, and 50 healthy Uyghur residents in Hotan Prefecture of Xinjiang Uygur Autonomous Region in May 2012.Thirty-one tagSNPs in PPARG gene were genotyped using Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry (MALDI-TOF-MS) method.The recombination hotspots and LD patterns within the PPARG gene were estimated by analyzing the SNP genotying data using the Hotspot Fisher program and Haploview software, respectively. Eighteen tagSNPs (rs1151999, rs1175540, rs1875796, rs1899951, rs2292101, rs2921190, rs2938397, rs2959272, rs2959273, rs2972162, rs3856806, rs4135247, rs4135275, rs709151, rs4135354, rs6805419, rs17036700 and rs4135304) were same with relatively higher recombination rates between the patients with type 2 diabetes mellitus (T2DM) and healthy controls of Kirgiz ethnic group, and healthy controls of Uyghur ethnic group.Five haplotype blocks with LD coefficient D' value of 1, indicating no genetic recombination occurred within the region, were observed in the healthy controls of Kirgiz ethnic groups, whereas five haplotype blocks with LD coefficient D' value less than 1 were observed in the Kirgiz patients with T2DM, indicating historical recombination events occurred within the region.Four haplotype blocks with LD coefficient D' value of 1 were observed in the Uyghur healthy controls, indicating no genetic recombination occurred within the region.There were significantly different recombination hotspot profiles between the Kirgiz, Uyghur, Utah residents with Northern and Western European ancestry (CEU), Yoruban in Ibadan, Nigeria (YRI) and Han Chinese in Beijing (CHB) and Japanese in Tokyo (JPT) samples.There are six recombination hotspots in the HapMap profile of genetic recombination.The last 5 SNPs within the PPARG gene were shown with lower recombination rates in the Kirgiz, whereas no recombination hotspot was found in the Uyghur. Variable recombination rates may be present in certain chromosome region between patients and healthy controls within the same or between the different ethnic groups.There may be presence of recombination hotspots of ethnic specificity and with variable recombination rates.

Using focus groups to design systems science models that promote oral health equity.

PubMed

Kum, Susan S; Northridge, Mary E; Metcalf, Sara S

2018-06-04

While the US population overall has experienced improvements in oral health over the past 60 years, oral diseases remain among the most common chronic conditions across the life course. Further, lack of access to oral health care contributes to profound and enduring oral health inequities worldwide. Vulnerable and underserved populations who commonly lack access to oral health care include racial/ethnic minority older adults living in urban environments. The aim of this study was to use a systematic approach to explicate cause and effect relationships in creating a causal map, a type of concept map in which the links between nodes represent causality or influence. To improve our mental models of the real world and devise strategies to promote oral health equity, methods including system dynamics, agent-based modeling, geographic information science, and social network simulation have been leveraged by the research team. The practice of systems science modeling is situated amidst an ongoing modeling process of observing the real world, formulating mental models of how it works, setting decision rules to guide behavior, and from these heuristics, making decisions that in turn affect the state of the real world. Qualitative data were obtained from focus groups conducted with community-dwelling older adults who self-identify as African American, Dominican, or Puerto Rican to elicit their lived experiences in accessing oral health care in their northern Manhattan neighborhoods. The findings of this study support the multi-dimensional and multi-level perspective of access to oral health care and affirm a theorized discrepancy in fit between available dental providers and patients. The lack of information about oral health at the community level may be compromising the use and quality of oral health care among racial/ethnic minority older adults. Well-informed community members may fill critical roles in oral health promotion, as they are viewed as highly credible sources of information and recommendations for dental providers. The next phase of this research will involve incorporating the knowledge gained from this study into simulation models that will be used to explore alternative paths toward improving oral health and health care for racial/ethnic minority older adults.

Estimating physiological skin parameters from hyperspectral signatures

NASA Astrophysics Data System (ADS)

Vyas, Saurabh; Banerjee, Amit; Burlina, Philippe

2013-05-01

We describe an approach for estimating human skin parameters, such as melanosome concentration, collagen concentration, oxygen saturation, and blood volume, using hyperspectral radiometric measurements (signatures) obtained from in vivo skin. We use a computational model based on Kubelka-Munk theory and the Fresnel equations. This model forward maps the skin parameters to a corresponding multiband reflectance spectra. Machine-learning-based regression is used to generate the inverse map, and hence estimate skin parameters from hyperspectral signatures. We test our methods using synthetic and in vivo skin signatures obtained in the visible through the short wave infrared domains from 24 patients of both genders and Caucasian, Asian, and African American ethnicities. Performance validation shows promising results: good agreement with the ground truth and well-established physiological precepts. These methods have potential use in the characterization of skin abnormalities and in minimally-invasive prescreening of malignant skin cancers.

Two Sources of the Russian Patrilineal Heritage in Their Eurasian Context

PubMed Central

Balanovsky, Oleg; Rootsi, Siiri; Pshenichnov, Andrey; Kivisild, Toomas; Churnosov, Michail; Evseeva, Irina; Pocheshkhova, Elvira; Boldyreva, Margarita; Yankovsky, Nikolay; Balanovska, Elena; Villems, Richard

2008-01-01

Progress in the mapping of population genetic substructure provides a core source of data for the reconstruction of the demographic history of our species and for the discovery of common signals relevant to disease research: These two aspects of enquiry overlap in their empirical data content and are especially informative at continental and subcontinental levels. In the present study of the variation of the Y chromosome pool of ethnic Russians, we show that the patrilineages within the pre-Ivan the Terrible historic borders of Russia have two main distinct sources. One of these antedates the linguistic split between West and East Slavonic-speaking people and is common for the two groups; the other is genetically highlighted by the pre-eminence of haplogroup (hg) N3 and is most parsimoniously explained by extensive assimilation of (or language change in) northeastern indigenous Finno-Ugric tribes. Although hg N3 is common for both East European and Siberian Y chromosomes, other typically Siberian or Mongolian hgs (Q and C) have negligible influence within the studied Russian Y chromosome pool. The distribution of all frequent Y chromosome haplogroups (which account for 95% of the Y chromosomal spectrum in Russians) follows a similar north-south clinal pattern among autosomal markers, apparent from synthetic maps. Multidimensional scaling (MDS) plots comparing intra ethnic and interethnic variation of Y chromosome in Europe show that although well detectable, intraethnic variation signals do not cross interethnic borders, except between Poles, Ukrainians, and central-southern Russians, thereby revealing their overwhelmingly shared patrilineal ancestry. PMID:18179905

Recruitment of racial and ethnic minorities to clinical trials conducted within specialty clinics: an intervention mapping approach.

PubMed

Amorrortu, Rossybelle P; Arevalo, Mariana; Vernon, Sally W; Mainous, Arch G; Diaz, Vanessa; McKee, M Diane; Ford, Marvella E; Tilley, Barbara C

2018-02-17

Despite efforts to increase diversity in clinical trials, racial/ethnic minority groups generally remain underrepresented, limiting researchers' ability to test the efficacy and safety of new interventions across diverse populations. We describe the use of a systematic framework, intervention mapping (IM), to develop an intervention to modify recruitment behaviors of coordinators and specialist investigators with the goal of increasing diversity in trials conducted within specialty clinics. To our knowledge IM has not been used in this setting. The IM framework was used to ensure that the intervention components were guided by health behavior theories and the evidence. The IM steps consisted of (1) conducting a needs assessment, (2) identification of determinants and objectives, (3) selection of theory-informed methods and practical applications, (4) development and creation of program components, (5) development of an adoption and implementation plan, and (6) creation of an evaluation plan. The intervention included five educational modules, one in-person and four web-based, plus technical assistance calls to coordinators. Modules addressed the intervention rationale, development of clinic-specific plans to obtain minority-serving physician referrals, physician-centered and patient-centered communication, and patient navigation. The evaluation, a randomized trial, was recently completed in 50 specialty clinics and is under analysis. Using IM we developed a recruitment intervention that focused on building relationships with minority-serving physicians to encourage minority patient referrals. IM enhanced our understanding of factors that may influence minority recruitment and helped us integrate strategies from multiple disciplines that were relevant for our audience.

Attitudes of Major Soviet Nationalities. Volume II. The Baltics. Estonia, Latvia, Lithuania.

DTIC Science & Technology

1973-06-01

acquired wide popularity (and probably snob appeal ). Kafka, Ionesco and Dostoyevsky were available to Soviet Estonians earlier than to the Russian reading...Estonia . chided as snob appeal ). Of Estonia’s 757 general schools, 556 (i.e. 71) use Estonian, 90 use Russian and 60 are mixed. 2 The same applies to...novels whicr combine literary quality with national appeal ro 2 ’), collective farm realism at its best (M. Traatl), realisti> lezcription of city life

Global Explosive Ordnance Disposal Conference and Exhibition Held in Fort Walton Beach, Florida on April 27-30, 2010

DTIC Science & Technology

2010-04-30

POLICY 24 Kagan ASP Response  21 Jul 08- ARCENT notified by Defense Attaché .  Uzbeks requested three types of equipment: land mine detectors...2 pax) on site.  21 Aug 08- the Training Team (5 pax) with equipment arrived in Uzbekistan.  28 Aug 08 all Uzbek / USEMB objectives were met...Slovakia, Spain, Poland Romania, United Kingdom, United States, Turkey Albania, Croatia Czech Republic, Hungary, Iceland, Czech Latvia, Lithuania

Industry turns its attention south

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marhefka, D.

1997-08-01

The paper discusses the outlook for the gas and oil industries in the Former Soviet Union and Eastern Europe. Significant foreign investment continues to elude Russia`s oil and gas industry, so the Caspian nations of Kazakhstan and Azerbaijan are picking up the slack, welcoming the flow of foreign capital to their energy projects. Separate evaluations are given for Russia, Azerbaijan, Kazakhstan, Turkmenistan, Ukraine, Armenia, Belarus, Georgia, Lithuania, Latvia, Estonia, Moldova, Tajikstan, Uzbekistan, Albania, Bulgaria, Croatia, Czech Republic, Hungary, Poland, Romania, Slovakia, Slovenia, and Serbia.

Mortality Disparities in Racial/Ethnic Minority Groups in the Veterans Health Administration: An Evidence Review and Map

PubMed Central

Anderson, Johanna; Boundy, Erin; Ferguson, Lauren; McCleery, Ellen; Waldrip, Kallie

2018-01-01

Background. Continued racial/ethnic health disparities were recently described as “the most serious and shameful health care issue of our time.” Although the 2014 US Affordable Care Act–mandated national insurance coverage expansion has led to significant improvements in health care coverage and access, its effects on life expectancy are not yet known. The Veterans Health Administration (VHA), the largest US integrated health care system, has a sustained commitment to health equity that addresses all 3 stages of health disparities research: detection, understanding determinants, and reduction or elimination. Despite this, racial disparities still exist in the VHA across a wide range of clinical areas and service types. Objectives. To inform the health equity research agenda, we synthesized evidence on racial/ethnic mortality disparities in the VHA. Search Methods. Our research librarian searched MEDLINE and Cochrane Central Registry of Controlled Trials from October 2006 through February 2017 using terms for racial groups and disparities. Selection Criteria. We included studies if they compared mortality between any racial/ethnic minority and nonminority veteran groups or between different minority groups in the VHA (PROSPERO# CRD42015015974). We made study selection decisions on the basis of prespecified eligibility criteria. They were first made by 1 reviewer and checked by a second and disagreements were resolved by consensus (sequential review). Data Collection and Analysis. Two reviewers sequentially abstracted data on prespecified population, outcome, setting, and study design characteristics. Two reviewers sequentially graded the strength of evidence using prespecified criteria on the basis of 5 key domains: study limitations (study design and internal validity), consistency, directness, precision of the evidence, and reporting biases. We synthesized the evidence qualitatively by grouping studies first by racial/ethnic minority group and then by clinical area. For areas with multiple studies in the same population and outcome, we pooled their reported hazard ratios (HRs) using random effects models (StatsDirect version 2.8.0; StatsDirect Ltd., Altrincham, England). We created an evidence map using a bubble plot format to represent the evidence base in 5 dimensions: odds ratio or HR of mortality for racial/ethnic minority group versus Whites, clinical area, strength of evidence, statistical significance, and racial group. Main Results. From 2840 citations, we included 25 studies. Studies were large (n ≥ 10 000) and involved nationally representative cohorts, and the majority were of fair quality. Most studies compared mortality between Black and White veterans and found similar or lower mortality for Black veterans. However, we found modest mortality disparities (HR or OR = 1.07, 1.52) for Black veterans with stage 4 chronic kidney disease, colon cancer, diabetes, HIV, rectal cancer, or stroke; for American Indian and Alaska Native veterans undergoing noncardiac major surgery; and for Hispanic veterans with HIV or traumatic brain injury (most low strength). Author’s Conclusions. Although the VHA’s equal access health care system has reduced many racial/ethnic mortality disparities present in the private sector, our review identified mortality disparities that have persisted mainly for Black veterans in several clinical areas. However, because most mortality disparities were supported by single studies with imprecise findings, we could not draw strong conclusions about this evidence. More disparities research is needed for American Indian and Alaska Native, Asian, and Hispanic veterans overall and for more of the largest life expectancy gaps. Public Health Implications. Because of the relatively high prevalence of diabetes in Black veterans, further research to better understand and reduce this mortality disparity may be prioritized as having the greatest potential impact. However, other mortality disparities affect thousands of veterans and cannot be ignored. PMID:29412713

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.

PubMed

Ng, Maggie C Y; Graff, Mariaelisa; Lu, Yingchang; Justice, Anne E; Mudgal, Poorva; Liu, Ching-Ti; Young, Kristin; Yanek, Lisa R; Feitosa, Mary F; Wojczynski, Mary K; Rand, Kristin; Brody, Jennifer A; Cade, Brian E; Dimitrov, Latchezar; Duan, Qing; Guo, Xiuqing; Lange, Leslie A; Nalls, Michael A; Okut, Hayrettin; Tajuddin, Salman M; Tayo, Bamidele O; Vedantam, Sailaja; Bradfield, Jonathan P; Chen, Guanjie; Chen, Wei-Min; Chesi, Alessandra; Irvin, Marguerite R; Padhukasahasram, Badri; Smith, Jennifer A; Zheng, Wei; Allison, Matthew A; Ambrosone, Christine B; Bandera, Elisa V; Bartz, Traci M; Berndt, Sonja I; Bernstein, Leslie; Blot, William J; Bottinger, Erwin P; Carpten, John; Chanock, Stephen J; Chen, Yii-Der Ida; Conti, David V; Cooper, Richard S; Fornage, Myriam; Freedman, Barry I; Garcia, Melissa; Goodman, Phyllis J; Hsu, Yu-Han H; Hu, Jennifer; Huff, Chad D; Ingles, Sue A; John, Esther M; Kittles, Rick; Klein, Eric; Li, Jin; McKnight, Barbara; Nayak, Uma; Nemesure, Barbara; Ogunniyi, Adesola; Olshan, Andrew; Press, Michael F; Rohde, Rebecca; Rybicki, Benjamin A; Salako, Babatunde; Sanderson, Maureen; Shao, Yaming; Siscovick, David S; Stanford, Janet L; Stevens, Victoria L; Stram, Alex; Strom, Sara S; Vaidya, Dhananjay; Witte, John S; Yao, Jie; Zhu, Xiaofeng; Ziegler, Regina G; Zonderman, Alan B; Adeyemo, Adebowale; Ambs, Stefan; Cushman, Mary; Faul, Jessica D; Hakonarson, Hakon; Levin, Albert M; Nathanson, Katherine L; Ware, Erin B; Weir, David R; Zhao, Wei; Zhi, Degui; Arnett, Donna K; Grant, Struan F A; Kardia, Sharon L R; Oloapde, Olufunmilayo I; Rao, D C; Rotimi, Charles N; Sale, Michele M; Williams, L Keoki; Zemel, Babette S; Becker, Diane M; Borecki, Ingrid B; Evans, Michele K; Harris, Tamara B; Hirschhorn, Joel N; Li, Yun; Patel, Sanjay R; Psaty, Bruce M; Rotter, Jerome I; Wilson, James G; Bowden, Donald W; Cupples, L Adrienne; Haiman, Christopher A; Loos, Ruth J F; North, Kari E

2017-04-01

Genome-wide association studies (GWAS) have identified >300 loci associated with measures of adiposity including body mass index (BMI) and waist-to-hip ratio (adjusted for BMI, WHRadjBMI), but few have been identified through screening of the African ancestry genomes. We performed large scale meta-analyses and replications in up to 52,895 individuals for BMI and up to 23,095 individuals for WHRadjBMI from the African Ancestry Anthropometry Genetics Consortium (AAAGC) using 1000 Genomes phase 1 imputed GWAS to improve coverage of both common and low frequency variants in the low linkage disequilibrium African ancestry genomes. In the sex-combined analyses, we identified one novel locus (TCF7L2/HABP2) for WHRadjBMI and eight previously established loci at P < 5×10-8: seven for BMI, and one for WHRadjBMI in African ancestry individuals. An additional novel locus (SPRYD7/DLEU2) was identified for WHRadjBMI when combined with European GWAS. In the sex-stratified analyses, we identified three novel loci for BMI (INTS10/LPL and MLC1 in men, IRX4/IRX2 in women) and four for WHRadjBMI (SSX2IP, CASC8, PDE3B and ZDHHC1/HSD11B2 in women) in individuals of African ancestry or both African and European ancestry. For four of the novel variants, the minor allele frequency was low (<5%). In the trans-ethnic fine mapping of 47 BMI loci and 27 WHRadjBMI loci that were locus-wide significant (P < 0.05 adjusted for effective number of variants per locus) from the African ancestry sex-combined and sex-stratified analyses, 26 BMI loci and 17 WHRadjBMI loci contained ≤ 20 variants in the credible sets that jointly account for 99% posterior probability of driving the associations. The lead variants in 13 of these loci had a high probability of being causal. As compared to our previous HapMap imputed GWAS for BMI and WHRadjBMI including up to 71,412 and 27,350 African ancestry individuals, respectively, our results suggest that 1000 Genomes imputation showed modest improvement in identifying GWAS loci including low frequency variants. Trans-ethnic meta-analyses further improved fine mapping of putative causal variants in loci shared between the African and European ancestry populations.

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

PubMed

Mahajan, Anubha; Go, Min Jin; Zhang, Weihua; Below, Jennifer E; Gaulton, Kyle J; Ferreira, Teresa; Horikoshi, Momoko; Johnson, Andrew D; Ng, Maggie C Y; Prokopenko, Inga; Saleheen, Danish; Wang, Xu; Zeggini, Eleftheria; Abecasis, Goncalo R; Adair, Linda S; Almgren, Peter; Atalay, Mustafa; Aung, Tin; Baldassarre, Damiano; Balkau, Beverley; Bao, Yuqian; Barnett, Anthony H; Barroso, Ines; Basit, Abdul; Been, Latonya F; Beilby, John; Bell, Graeme I; Benediktsson, Rafn; Bergman, Richard N; Boehm, Bernhard O; Boerwinkle, Eric; Bonnycastle, Lori L; Burtt, Noël; Cai, Qiuyin; Campbell, Harry; Carey, Jason; Cauchi, Stephane; Caulfield, Mark; Chan, Juliana C N; Chang, Li-Ching; Chang, Tien-Jyun; Chang, Yi-Cheng; Charpentier, Guillaume; Chen, Chien-Hsiun; Chen, Han; Chen, Yuan-Tsong; Chia, Kee-Seng; Chidambaram, Manickam; Chines, Peter S; Cho, Nam H; Cho, Young Min; Chuang, Lee-Ming; Collins, Francis S; Cornelis, Marylin C; Couper, David J; Crenshaw, Andrew T; van Dam, Rob M; Danesh, John; Das, Debashish; de Faire, Ulf; Dedoussis, George; Deloukas, Panos; Dimas, Antigone S; Dina, Christian; Doney, Alex S; Donnelly, Peter J; Dorkhan, Mozhgan; van Duijn, Cornelia; Dupuis, Josée; Edkins, Sarah; Elliott, Paul; Emilsson, Valur; Erbel, Raimund; Eriksson, Johan G; Escobedo, Jorge; Esko, Tonu; Eury, Elodie; Florez, Jose C; Fontanillas, Pierre; Forouhi, Nita G; Forsen, Tom; Fox, Caroline; Fraser, Ross M; Frayling, Timothy M; Froguel, Philippe; Frossard, Philippe; Gao, Yutang; Gertow, Karl; Gieger, Christian; Gigante, Bruna; Grallert, Harald; Grant, George B; Grrop, Leif C; Groves, Chrisropher J; Grundberg, Elin; Guiducci, Candace; Hamsten, Anders; Han, Bok-Ghee; Hara, Kazuo; Hassanali, Neelam; Hattersley, Andrew T; Hayward, Caroline; Hedman, Asa K; Herder, Christian; Hofman, Albert; Holmen, Oddgeir L; Hovingh, Kees; Hreidarsson, Astradur B; Hu, Cheng; Hu, Frank B; Hui, Jennie; Humphries, Steve E; Hunt, Sarah E; Hunter, David J; Hveem, Kristian; Hydrie, Zafar I; Ikegami, Hiroshi; Illig, Thomas; Ingelsson, Erik; Islam, Muhammed; Isomaa, Bo; Jackson, Anne U; Jafar, Tazeen; James, Alan; Jia, Weiping; Jöckel, Karl-Heinz; Jonsson, Anna; Jowett, Jeremy B M; Kadowaki, Takashi; Kang, Hyun Min; Kanoni, Stavroula; Kao, Wen Hong L; Kathiresan, Sekar; Kato, Norihiro; Katulanda, Prasad; Keinanen-Kiukaanniemi, Kirkka M; Kelly, Ann M; Khan, Hassan; Khaw, Kay-Tee; Khor, Chiea-Chuen; Kim, Hyung-Lae; Kim, Sangsoo; Kim, Young Jin; Kinnunen, Leena; Klopp, Norman; Kong, Augustine; Korpi-Hyövälti, Eeva; Kowlessur, Sudhir; Kraft, Peter; Kravic, Jasmina; Kristensen, Malene M; Krithika, S; Kumar, Ashish; Kumate, Jesus; Kuusisto, Johanna; Kwak, Soo Heon; Laakso, Markku; Lagou, Vasiliki; Lakka, Timo A; Langenberg, Claudia; Langford, Cordelia; Lawrence, Robert; Leander, Karin; Lee, Jen-Mai; Lee, Nanette R; Li, Man; Li, Xinzhong; Li, Yun; Liang, Junbin; Liju, Samuel; Lim, Wei-Yen; Lind, Lars; Lindgren, Cecilia M; Lindholm, Eero; Liu, Ching-Ti; Liu, Jian Jun; Lobbens, Stéphane; Long, Jirong; Loos, Ruth J F; Lu, Wei; Luan, Jian'an; Lyssenko, Valeriya; Ma, Ronald C W; Maeda, Shiro; Mägi, Reedik; Männisto, Satu; Matthews, David R; Meigs, James B; Melander, Olle; Metspalu, Andres; Meyer, Julia; Mirza, Ghazala; Mihailov, Evelin; Moebus, Susanne; Mohan, Viswanathan; Mohlke, Karen L; Morris, Andrew D; Mühleisen, Thomas W; Müller-Nurasyid, Martina; Musk, Bill; Nakamura, Jiro; Nakashima, Eitaro; Navarro, Pau; Ng, Peng-Keat; Nica, Alexandra C; Nilsson, Peter M; Njølstad, Inger; Nöthen, Markus M; Ohnaka, Keizo; Ong, Twee Hee; Owen, Katharine R; Palmer, Colin N A; Pankow, James S; Park, Kyong Soo; Parkin, Melissa; Pechlivanis, Sonali; Pedersen, Nancy L; Peltonen, Leena; Perry, John R B; Peters, Annette; Pinidiyapathirage, Janini M; Platou, Carl G; Potter, Simon; Price, Jackie F; Qi, Lu; Radha, Venkatesan; Rallidis, Loukianos; Rasheed, Asif; Rathman, Wolfgang; Rauramaa, Rainer; Raychaudhuri, Soumya; Rayner, N William; Rees, Simon D; Rehnberg, Emil; Ripatti, Samuli; Robertson, Neil; Roden, Michael; Rossin, Elizabeth J; Rudan, Igor; Rybin, Denis; Saaristo, Timo E; Salomaa, Veikko; Saltevo, Juha; Samuel, Maria; Sanghera, Dharambir K; Saramies, Jouko; Scott, James; Scott, Laura J; Scott, Robert A; Segrè, Ayellet V; Sehmi, Joban; Sennblad, Bengt; Shah, Nabi; Shah, Sonia; Shera, A Samad; Shu, Xiao Ou; Shuldiner, Alan R; Sigurđsson, Gunnar; Sijbrands, Eric; Silveira, Angela; Sim, Xueling; Sivapalaratnam, Suthesh; Small, Kerrin S; So, Wing Yee; Stančáková, Alena; Stefansson, Kari; Steinbach, Gerald; Steinthorsdottir, Valgerdur; Stirrups, Kathleen; Strawbridge, Rona J; Stringham, Heather M; Sun, Qi; Suo, Chen; Syvänen, Ann-Christine; Takayanagi, Ryoichi; Takeuchi, Fumihiko; Tay, Wan Ting; Teslovich, Tanya M; Thorand, Barbara; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Tikkanen, Emmi; Trakalo, Joseph; Tremoli, Elena; Trip, Mieke D; Tsai, Fuu Jen; Tuomi, Tiinamaija; Tuomilehto, Jaakko; Uitterlinden, Andre G; Valladares-Salgado, Adan; Vedantam, Sailaja; Veglia, Fabrizio; Voight, Benjamin F; Wang, Congrong; Wareham, Nicholas J; Wennauer, Roman; Wickremasinghe, Ananda R; Wilsgaard, Tom; Wilson, James F; Wiltshire, Steven; Winckler, Wendy; Wong, Tien Yin; Wood, Andrew R; Wu, Jer-Yuarn; Wu, Ying; Yamamoto, Ken; Yamauchi, Toshimasa; Yang, Mingyu; Yengo, Loic; Yokota, Mitsuhiro; Young, Robin; Zabaneh, Delilah; Zhang, Fan; Zhang, Rong; Zheng, Wei; Zimmet, Paul Z; Altshuler, David; Bowden, Donald W; Cho, Yoon Shin; Cox, Nancy J; Cruz, Miguel; Hanis, Craig L; Kooner, Jaspal; Lee, Jong-Young; Seielstad, Mark; Teo, Yik Ying; Boehnke, Michael; Parra, Esteban J; Chambers, Jonh C; Tai, E Shyong; McCarthy, Mark I; Morris, Andrew P

2014-03-01

To further understanding of the genetic basis of type 2 diabetes (T2D) susceptibility, we aggregated published meta-analyses of genome-wide association studies (GWAS), including 26,488 cases and 83,964 controls of European, east Asian, south Asian and Mexican and Mexican American ancestry. We observed a significant excess in the directional consistency of T2D risk alleles across ancestry groups, even at SNPs demonstrating only weak evidence of association. By following up the strongest signals of association from the trans-ethnic meta-analysis in an additional 21,491 cases and 55,647 controls of European ancestry, we identified seven new T2D susceptibility loci. Furthermore, we observed considerable improvements in the fine-mapping resolution of common variant association signals at several T2D susceptibility loci. These observations highlight the benefits of trans-ethnic GWAS for the discovery and characterization of complex trait loci and emphasize an exciting opportunity to extend insight into the genetic architecture and pathogenesis of human diseases across populations of diverse ancestry.

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

PubMed Central

2014-01-01

To further understanding of the genetic basis of type 2 diabetes (T2D) susceptibility, we aggregated published meta-analyses of genome-wide association studies (GWAS) including 26,488 cases and 83,964 controls of European, East Asian, South Asian, and Mexican and Mexican American ancestry. We observed significant excess in directional consistency of T2D risk alleles across ancestry groups, even at SNPs demonstrating only weak evidence of association. By following up the strongest signals of association from the trans-ethnic meta-analysis in an additional 21,491 cases and 55,647 controls of European ancestry, we identified seven novel T2D susceptibility loci. Furthermore, we observed considerable improvements in fine-mapping resolution of common variant association signals at several T2D susceptibility loci. These observations highlight the benefits of trans-ethnic GWAS for the discovery and characterisation of complex trait loci, and emphasize an exciting opportunity to extend insight into the genetic architecture and pathogenesis of human diseases across populations of diverse ancestry. PMID:24509480

Comparison of genetic variations of the SLCO1B1, SLCO1B3, and SLCO2B1 genes among five ethnic groups.

PubMed

Namgoong, Suhg; Cheong, Hyun Sub; Kim, Ji On; Kim, Lyoung Hyo; Na, Han Sung; Koh, In Song; Chung, Myeon Woo; Shin, Hyoung Doo

2015-11-01

Organic anion-transporting polypeptide (OATP; gene symbol, SLCO) transporters are generally involved in the uptake of multiple drugs and their metabolites at most epithelial barriers. The pattern of single-nucleotide polymorphisms (SNPs) in these transporters may be determinants of interindividual variability in drug disposition and response. The objective of this study was to define the distribution of SNPs of three SLCO genes, SLCO1B1, SLCO1B3, and SLCO2B1, in a Korean population and other ethnic groups. The study was screened using the Illumina GoldenGate assay for genomic DNA from 450 interethnic subjects, including 11 pharmacogenetic core variants and 76 HapMap tagging SNPs. The genotype distribution of the Korean population was similar to East Asian populations, but significantly different from African American and European American cohorts. These interethnic differences will be useful information for prospective studies, including genetic association and pharmacogenetic studies of drug metabolism by SLCO families. Copyright © 2015 Elsevier B.V. All rights reserved.

Analysis of the genetic structure of the Malay population: Ancestry-informative marker SNPs in the Malay of Peninsular Malaysia.

PubMed

Yahya, Padillah; Sulong, Sarina; Harun, Azian; Wan Isa, Hatin; Ab Rajab, Nur-Shafawati; Wangkumhang, Pongsakorn; Wilantho, Alisa; Ngamphiw, Chumpol; Tongsima, Sissades; Zilfalil, Bin Alwi

2017-09-01

Malay, the main ethnic group in Peninsular Malaysia, is represented by various sub-ethnic groups such as Melayu Banjar, Melayu Bugis, Melayu Champa, Melayu Java, Melayu Kedah Melayu Kelantan, Melayu Minang and Melayu Patani. Using data retrieved from the MyHVP (Malaysian Human Variome Project) database, a total of 135 individuals from these sub-ethnic groups were profiled using the Affymetrix GeneChip Mapping Xba 50-K single nucleotide polymorphism (SNP) array to identify SNPs that were ancestry-informative markers (AIMs) for Malays of Peninsular Malaysia. Prior to selecting the AIMs, the genetic structure of Malays was explored with reference to 11 other populations obtained from the Pan-Asian SNP Consortium database using principal component analysis (PCA) and ADMIXTURE. Iterative pruning principal component analysis (ipPCA) was further used to identify sub-groups of Malays. Subsequently, we constructed an AIMs panel for Malays using the informativeness for assignment (I n ) of genetic markers, and the K-nearest neighbor classifier (KNN) was used to teach the classification models. A model of 250 SNPs ranked by I n , correctly classified Malay individuals with an accuracy of up to 90%. The identified panel of SNPs could be utilized as a panel of AIMs to ascertain the specific ancestry of Malays, which may be useful in disease association studies, biomedical research or forensic investigation purposes. Copyright © 2017 Elsevier B.V. All rights reserved.

Patterns of population differentiation of candidate genes for cardiovascular disease.

PubMed

Kullo, Iftikhar J; Ding, Keyue

2007-07-12

The basis for ethnic differences in cardiovascular disease (CVD) susceptibility is not fully understood. We investigated patterns of population differentiation (FST) of a set of genes in etiologic pathways of CVD among 3 ethnic groups: Yoruba in Nigeria (YRI), Utah residents with European ancestry (CEU), and Han Chinese (CHB) + Japanese (JPT). We identified 37 pathways implicated in CVD based on the PANTHER classification and 416 genes in these pathways were further studied; these genes belonged to 6 biological processes (apoptosis, blood circulation and gas exchange, blood clotting, homeostasis, immune response, and lipoprotein metabolism). Genotype data were obtained from the HapMap database. We calculated FST for 15,559 common SNPs (minor allele frequency > or = 0.10 in at least one population) in genes that co-segregated among the populations, as well as an average-weighted FST for each gene. SNPs were classified as putatively functional (non-synonymous and untranslated regions) or non-functional (intronic and synonymous sites). Mean FST values for common putatively functional variants were significantly higher than FST values for nonfunctional variants. A significant variation in FST was also seen based on biological processes; the processes of 'apoptosis' and 'lipoprotein metabolism' showed an excess of genes with high FST. Thus, putative functional SNPs in genes in etiologic pathways for CVD show greater population differentiation than non-functional SNPs and a significant variance of FST values was noted among pairwise population comparisons for different biological processes. These results suggest a possible basis for varying susceptibility to CVD among ethnic groups.

Investigations of the unsaturated zone at two radioactive waste disposal sites in Lithuania.

PubMed

Skuratovič, Žana; Mažeika, Jonas; Petrošius, Rimantas; Martma, Tõnu

2016-01-01

The unsaturated zone is an important part of the water cycle, governed by many hydrological and hydrogeological factors and processes and provide water and nutrients to the terrestrial ecosystem. Besides, the soils of the unsaturated zone are regarded as the first natural barrier to a large extent and are able to limit the spread of contaminants depending on their properties. The unsaturated zone provides a linkage between atmospheric moisture, groundwater, and seepage of groundwater to streams, lakes, or other surface water bodies. The major difference between water flow in saturated and unsaturated soils is that the hydraulic conductivity, which is conventionally assumed to be a constant in saturated soils, is a function of the degree of saturation or matrix suction in the unsaturated soils. In Lithuania, low and intermediate level radioactive wastes generated from medicine, industry and research were accumulated at the Maisiagala radioactive waste repository. Short-lived low and intermediate levels radioactive waste, generated during the operation of the Ignalina Nuclear Power Plant (INPP) and arising after the INPP decommissioning will be disposed of in the near surface repository close to the INPP (Stabatiske site). Extensive data sets of the hydraulic properties and water content attributed to unsaturated zone soil profiles of the two radioactive waste disposal sites have been collected and summarized. Globally widespread radionuclide tritium ((3)H) and stable isotope ratio ((18)O/(16)O and (2)H/(1)H) distribution features were determined in precipitation, unsaturated zone soil moisture profiles and groundwater.

Leadership styles in ethical dilemmas when head nurses make decisions.

PubMed

Zydziunaite, V; Lepaite, D; Suominen, T

2013-06-01

The overlooked aspect in Lithuania is the dearth of leaders among head nurses, who bear the responsibility for decisions in ethical dilemmas. Understanding the application of leadership styles is fundamental to ensuring head nurses' abilities to influence outcomes for healthcare providers and patients. To identify the leadership styles applied by head nurses in decision making in ethical dilemmas on hospital wards. The data were collected by questionnaires completed by head nurses (n = 278) working in five major state-funded hospitals in each of the five regions of Lithuania. The data were analysed using SPSS 16.0, calculating descriptive statistics and analysis of variance. Head nurses apply democratic, affiliative, transformational and sustainable leadership styles when resolving ethical dilemmas. The application of leadership styles is associated not only with specific situations, but also with certain background factors, such as years of experience in a head nurse's position, ward specialization and the incidence of ethical dilemmas. Nurses having been in a head nurse's position over 10 years use primitive leadership styles, notably bureaucratic leadership, more often than do those head nurses with only a few years of experience in such a position. The results highlight the need for head nurses to reflect on their practices and to find new ways of learning from practice, colleagues and patients. Head nurses' managerial decisions due to their 'executive power' can turn into a new state-of-the-art leadership in nursing. © 2013 The Authors. International Nursing Review © 2013 International Council of Nurses.

Radionuclides in the ground-level atmosphere in Vilnius, Lithuania, in March 2011, detected by gamma-ray spectrometry.

PubMed

Gudelis, A; Druteikienė, R; Lujanienė, G; Maceika, E; Plukis, A; Remeikis, V

2012-07-01

This study presents the ground-level air monitoring results obtained in Vilnius, the capital of Lithuania, on 14 March-14 April 2011 after the recent earthquake and subsequent Tsunami having a crucial impact on Japanese nuclear reactors at the Fukushima Daiichi Nuclear Power Plant (NPP) on 11 March 2011. To collect representative diurnal aerosol samples a powerful sampling system ensuring the air filtration rate of 5500 m(3) h(-1) was used. The following artificial gamma-ray emitting radionuclides have been determined: (129m)Te, (132)Te (in equilibrium with its daughter (132)I), (131)I, (134)Cs, (136)Cs and (137)Cs. Activity concentration of the globally distributed fission product (137)Cs has increased from a background value of 1.6 μBq m(-3) to the value of 0.9 mBq m(-3) at the beginning of April. The activity ratio (134)Cs/(137)Cs was found to be close to 1, with a slightly higher activity of (134)Cs. The maximum aerosol-associated (131)I activity concentration of 3.45 mBq m(-3) was by four orders of magnitude lower than that measured at the same location in April-May 1986 as a consequence of the Chernobyl NPP accident. The estimated gaseous fraction of iodine-131 constituted about 70% of the total (131)I activity. Copyright © 2011 Elsevier Ltd. All rights reserved.

Cancer incidence among women flax textile manufacturing workers in Lithuania.

PubMed

Kuzmickiene, Irena; Stukonis, Mecys

2010-07-01

To determine site-specific cancer incidence among women spinning-weaving and dyeing-finishing workers in the largest flax textile factory in Lithuania. The cancer incidence of a cohort of 3447 women workers from a flax textile factory was investigated for the period 1978-2002. All subjects were employed at the plant in the period 1957-2000 for a minimum of 12 months. Standardised incidence ratios (SIRs) were estimated by use of the corresponding national rates. SIRs were calculated for the spinning-weaving and dyeing-finishing work categories, and for two durations of employment categories (<10 years, > or =10 years). The cancer SIRs among spinning-weaving and dyeing-finishing workers were 0.84 (95% CI 0.69 to 1.00) and 0.90 (95% CI 0.52 to 1.44). An incidence deficit for non-melanoma skin cancer was found for the spinning-weaving unit (SIR 0.45, 95% CI 0.18 to 0.92). The risk of oral cavity and pharynx cancer was significantly increased in spinning-weaving unit workers with <10 years of employment (SIR 5.71, 95% CI 1.56 to 14.60). A significant excess of thyroid cancer and nervous system cancer was found among dyeing-finishing workers. The overall cancer and non-melanoma skin cancer incidence rate among flax spinning-weaving workers was lower compared with the Lithuanian population. The present findings lend some support to an excess of thyroid and nervous system cancers among dyeing-finishing workers and of oral cavity and pharynx cancer in spinning-weaving workers.

The inability to pay for health services in Central and Eastern Europe: evidence from six countries

PubMed Central

Pavlova, Milena; Rechel, Bernd; Golinowska, Stanisława; Sowada, Christoph; Groot, Wim

2014-01-01

Background: Out-of-pocket payments for health services constitute a major financial burden for patients in Central and Eastern European (CEE) countries. Individuals who are unable to pay use different coping strategies (e.g. borrowing money or foregoing service utilization), which can have negative consequences on their health and social welfare. This article explores patients’ inability to pay for outpatient and hospital services in six CEE countries: Bulgaria, Hungary, Lithuania, Poland, Romania and Ukraine. Methods: The analysis is based on quantitative data collected in 2010 in nationally representative surveys. Two indicators of inability to pay were considered: the need to borrow money or sell assets and foregoing service utilization. Statistical analyses were applied to investigate associations between the indicators of inability to pay and individual characteristics. Results: Patient payments are most common in Bulgaria, Ukraine, Romania and Lithuania and often include informal payments. Romanian and, particularly, Ukrainian patients most often face difficulties to pay for health services (with approximately 40% of Ukrainian payers borrowing money or selling assets to cover hospital payments and approximately 60% of respondents who need care foregoing services). Inability to pay mainly affects those with poor health and low incomes. Conclusion: Widespread patient payments constitute a major financial barrier to health service use in CEE. There is a need to formalize them where they are informal and to take measures to protect vulnerable population groups, especially those with limited possibilities to deal with payment difficulties. PMID:24065370

Prevalence of Dental Erosion among the Young Regular Swimmers in Kaunas, Lithuania.

PubMed

Zebrauskas, Andrius; Birskute, Ruta; Maciulskiene, Vita

2014-04-01

To determine prevalence of dental erosion among competitive swimmers in Kaunas, the second largest city in Lithuania. The study was designed as a cross-sectional survey, with a questionnaire and clinical examination protocols. The participants were 12 - 25 year-old swimmers regularly practicing in the swimming pools of Kaunas. Of the total of 132 participants there were 76 (12 - 17 year-old) and 56 (18 - 25 year-old) individuals; in Groups 1 and 2, respectively. Participants were examined for dental erosion, using a portable dental unit equipped with fibre-optic light, compressed air and suction, and standard dental instruments for oral inspection. Lussi index was applied for recording dental erosion. The completed questionnaires focused on the common erosion risk factors were returned by all participants. Dental erosion was found in 25% of the 12 - 17 year-olds, and in 50% of 18 - 25 years-olds. Mean value of the surfaces with erosion was 6.31 (SD 4.37). All eroded surfaces were evaluated as grade 1. Swimming training duration and the participants' age correlated positively (Kendall correlation, r = 0.65, P < 0.001), meaning that older swimmers had practiced for longer period. No significant correlation between occurrence of dental erosion and the analyzed risk factors (gastroesophageal reflux disease, frequent vomiting, dry mouth, regular intake of acidic medicines, carbonated drinks) was found in both study groups. Prevalence of dental erosion of very low degree was high among the regular swimmers in Kaunas, and was significantly related to swimmers' age.

Family Social Environment and Parenting Predictors of Alcohol Use among Adolescents in Lithuania.

PubMed

Šumskas, Linas; Zaborskis, Apolinaras

2017-09-08

The role of the family as the social environment in shaping adolescent lifestyle has recently received substantial attention. This study was focused on investigating the association between familial and parenting predictors and alcohol use in school-aged children. Adolescents aged 13- and 15-year from a representative sample (N = 3715) of schools in Lithuania were surveyed during the spring of 2014. The methodology of the cross-national Health Behaviour in School-aged Children (HBSC) study was applied. HBSC international questionnaires were completed in the classroom anonymously for obtaining information about drinking of alcoholic beverages and family characteristics-family's affluence and structure, style of communication in the family, parenting style, parental monitoring, family time together, etc. Univariate and multivariate logistic regression analysis was applied for assessment of the association between familial variables and weekly alcohol use. Analysis has demonstrated that adolescents from non-intact families tended to show significantly higher risk of being weekly drinkers (OR = 1.69; 95% CI: 1.30-2.19). The following parenting factors were associated with weekly use of alcohol: father's and mother's low monitoring, father's authoritarian-repressive and mother's permissive-neglectful parenting style. Frequent family time together and frequent electronic media communication with parents showed an inverse negative effect than was predicted. The study suggests that alcohol misuse among adolescents could be associated with a non-intact family structure as well as with complex family and parenting determinants which should be investigated more thoroughly by further studies.

Biomedical physics in continuing medical education: an analysis of learning needs.

PubMed

Rotomskis, Ricardas; Karenauskaite, Violeta; Balzekiene, Aiste

2009-01-01

To examine the learning and practice needs of medical professionals in the field of continuing education of biomedical physics in Lithuania. The study was based on a questionnaire survey of 309 medical professionals throughout Lithuania, 3 focus group discussions, and 18 interviews with medical and physics experts. The study showed that medical professionals lack knowledge of physics: only 15.1% of the respondents admitted that they had enough knowledge in biomedical physics to understand the functioning of the medical devices that they used, and 7.5% of respondents indicated that they had enough knowledge to understand and adopt medical devices of the new generation. Physics knowledge was valued more highly by medical professionals with scientific degrees. As regards continuing medical education, it was revealed that personal motivation (88.7%) and responsibility for patients (44.3%) were the most important motives for upgrading competencies, whereas workload (65.4%) and financial limits (45.3%) were the main obstacles. The most popular teaching methods were those based on practical work (78.9%), and the least popular was project work (27.8%). The study revealed that biomedical physics knowledge was needed in both specializations and practical work, and the most important factor for determining its need was professional aspirations. Medical professionals' understanding of medical devices, especially those of the new generation, is essentially functional in nature. Professional upgrading courses contain only fragmented biomedical physics content, and new courses should be developed jointly by experts in physics and medicine to meet the specialized needs of medical professionals.

Assessment of nutrition and physical activity of 6th–7th grade schoolchildren in the city of Vilnius, Lithuania

PubMed Central

Skurdenyte, Vaida; Surkiene, Gene; Stukas, Rimantas; Zagminas, Kestutis; Giedraitis, Vincentas

2015-01-01

Background Evaluation of eating habits and physical activity is very important for health interventions. Our aim in this study was to assess the characteristics of eating and physical activity of 6–7th grade schoolchildren in the city of Vilnius, Lithuania, as well as the association between dietary habits and physical activity. Methods The study was conducted within the project “Education of healthy diets and physical activity in schools”. The sample consisted of 1008 schoolchildren from 22 schools in the city of Vilnius, and was based on empirical methods, including a questionnaire poll and comparative analysis. Statistical software Stata v.12.1 (Stata corp LP) was used to analyze the data. Results Our study showed that less than half (37.1%) of study participants had physically active leisure time. Boys were significantly more physically active than girls. More than half (61.4%) of children ate breakfast every day. Girls were more likely to eat vegetables and sweets. Schoolchildren who ate vegetables and dairy products as well as those who got enough information about physical activity and spoke about it with their family members were more physically active. Conclusions The results of the study confirmed that schoolchildren were not sufficiently physically active. It was found that low physical activity is related to dietary and other factors, such as lack of information about physical activity and its benefits. PMID:28352688

Family Social Environment and Parenting Predictors of Alcohol Use among Adolescents in Lithuania

PubMed Central

Šumskas, Linas; Zaborskis, Apolinaras

2017-01-01

The role of the family as the social environment in shaping adolescent lifestyle has recently received substantial attention. This study was focused on investigating the association between familial and parenting predictors and alcohol use in school-aged children. Adolescents aged 13- and 15-year from a representative sample (N = 3715) of schools in Lithuania were surveyed during the spring of 2014. The methodology of the cross-national Health Behaviour in School-aged Children (HBSC) study was applied. HBSC international questionnaires were completed in the classroom anonymously for obtaining information about drinking of alcoholic beverages and family characteristics—family’s affluence and structure, style of communication in the family, parenting style, parental monitoring, family time together, etc. Univariate and multivariate logistic regression analysis was applied for assessment of the association between familial variables and weekly alcohol use. Analysis has demonstrated that adolescents from non-intact families tended to show significantly higher risk of being weekly drinkers (OR = 1.69; 95% CI: 1.30–2.19). The following parenting factors were associated with weekly use of alcohol: father’s and mother’s low monitoring, father’s authoritarian-repressive and mother’s permissive-neglectful parenting style. Frequent family time together and frequent electronic media communication with parents showed an inverse negative effect than was predicted. The study suggests that alcohol misuse among adolescents could be associated with a non-intact family structure as well as with complex family and parenting determinants which should be investigated more thoroughly by further studies. PMID:28885599

Individual exposures to drinking water trihalomethanes, low birth weight and small for gestational age risk: a prospective Kaunas cohort study.

PubMed

Grazuleviciene, Regina; Nieuwenhuijsen, Mark J; Vencloviene, Jone; Kostopoulou-Karadanelli, Maria; Krasner, Stuart W; Danileviciute, Asta; Balcius, Gediminas; Kapustinskiene, Violeta

2011-04-19

Evidence for an association between exposure during pregnancy to trihalomethanes (THMs) in drinking water and impaired fetal growth is still inconsistent and inconclusive, in particular, for various exposure routes. We examined the relationship of individual exposures to THMs in drinking water on low birth weight (LBW), small for gestational age (SGA), and birth weight (BW) in singleton births. We conducted a cohort study of 4,161 pregnant women in Kaunas (Lithuania), using individual information on drinking water, ingestion, showering and bathing, and uptake factors of THMs in blood, to estimate an internal dose of THM. We used regression analysis to evaluate the relationship between internal THM dose and birth outcomes, adjusting for family status, education, smoking, alcohol consumption, body mass index, blood pressure, ethnic group, previous preterm, infant gender, and birth year. The estimated internal dose of THMs ranged from 0.0025 to 2.40 mg/d. We found dose-response relationships for the entire pregnancy and trimester-specific THM and chloroform internal dose and risk for LBW and a reduction in BW. The adjusted odds ratio for third tertile vs. first tertile chloroform internal dose of entire pregnancy was 2.17, 95% CI 1.19-3.98 for LBW; the OR per every 0.1 μg/d increase in chloroform internal dose was 1.10, 95% CI 1.01-1.19. Chloroform internal dose was associated with a slightly increased risk of SGA (OR 1.19, 95% CI 0.87-1.63 and OR 1.22, 95% CI 0.89-1.68, respectively, for second and third tertile of third trimester); the risk increased by 4% per every 0.1 μg/d increase in chloroform internal dose (OR 1.04, 95% CI 1.00-1.09). THM internal dose in pregnancy varies substantially across individuals, and depends on both water THM levels and water use habits. Increased internal dose may affect fetal growth.

Individual exposures to drinking water trihalomethanes, low birth weight and small for gestational age risk: a prospective Kaunas cohort study

PubMed Central

2011-01-01

Background Evidence for an association between exposure during pregnancy to trihalomethanes (THMs) in drinking water and impaired fetal growth is still inconsistent and inconclusive, in particular, for various exposure routes. We examined the relationship of individual exposures to THMs in drinking water on low birth weight (LBW), small for gestational age (SGA), and birth weight (BW) in singleton births. Methods We conducted a cohort study of 4,161 pregnant women in Kaunas (Lithuania), using individual information on drinking water, ingestion, showering and bathing, and uptake factors of THMs in blood, to estimate an internal dose of THM. We used regression analysis to evaluate the relationship between internal THM dose and birth outcomes, adjusting for family status, education, smoking, alcohol consumption, body mass index, blood pressure, ethnic group, previous preterm, infant gender, and birth year. Results The estimated internal dose of THMs ranged from 0.0025 to 2.40 mg/d. We found dose-response relationships for the entire pregnancy and trimester-specific THM and chloroform internal dose and risk for LBW and a reduction in BW. The adjusted odds ratio for third tertile vs. first tertile chloroform internal dose of entire pregnancy was 2.17, 95% CI 1.19-3.98 for LBW; the OR per every 0.1 μg/d increase in chloroform internal dose was 1.10, 95% CI 1.01-1.19. Chloroform internal dose was associated with a slightly increased risk of SGA (OR 1.19, 95% CI 0.87-1.63 and OR 1.22, 95% CI 0.89-1.68, respectively, for second and third tertile of third trimester); the risk increased by 4% per every 0.1 μg/d increase in chloroform internal dose (OR 1.04, 95% CI 1.00-1.09). Conclusions THM internal dose in pregnancy varies substantially across individuals, and depends on both water THM levels and water use habits. Increased internal dose may affect fetal growth. PMID:21501533

Prevalence and phylogenetic analysis of hepatitis E virus in pigs, wild boars, roe deer, red deer and moose in Lithuania.

PubMed

Spancerniene, Ugne; Grigas, Juozas; Buitkuviene, Jurate; Zymantiene, Judita; Juozaitiene, Vida; Stankeviciute, Milda; Razukevicius, Dainius; Zienius, Dainius; Stankevicius, Arunas

2018-02-23

Hepatitis E virus (HEV) is one of the major causes of acute viral hepatitis worldwide. In Europe, food-borne zoonotic transmission of HEV genotype 3 has been associated with domestic pigs and wild boar. Controversial data are available on the circulation of the virus in animals that are used for human consumption, and to date, no gold standard has yet been defined for the diagnosis of HEV-associated hepatitis. To investigate the current HEV infection status in Lithuanian pigs and wild ungulates, the presence of viral RNA was analyzed by nested reverse transcription polymerase chain reaction (RT-nPCR) in randomly selected samples, and the viral RNA was subsequently genotyped. In total, 32.98 and 22.55% of the domestic pig samples were HEV-positive using RT-nPCR targeting the ORF1 and ORF2 fragments, respectively. Among ungulates, 25.94% of the wild boar samples, 22.58% of the roe deer samples, 6.67% of the red deer samples and 7.69% of the moose samples were positive for HEV RNA using primers targeting the ORF1 fragment. Using primers targeting the ORF2 fragment of the HEV genome, viral RNA was only detected in 17.03% of the wild boar samples and 12.90% of the roe deer samples. Phylogenetic analysis based on a 348-nucleotide-long region of the HEV ORF2 showed that all obtained sequences detected in Lithuanian domestic pigs and wildlife belonged to genotype 3. In this study, the sequences identified from pigs, wild boars and roe deer clustered within the 3i subtype reference sequences from the GenBank database. The sequences obtained from pig farms located in two different counties of Lithuania were of the HEV 3f subtype. The wild boar sequences clustered within subtypes 3i and 3h, clearly indicating that wild boars can harbor additional subtypes of HEV. For the first time, the ORF2 nucleotide sequences obtained from roe deer proved that HEV subtype 3i can be found in a novel host. The results of the viral prevalence and phylogenetic analyses clearly demonstrated viral infection in Lithuanian pigs and wild ungulates, thus highlighting a significant concern for zoonotic virus transmission through both the food chain and direct contact with animals. Unexpected HEV genotype 3 subtype diversity in Lithuania and neighboring countries revealed that further studies are necessary to understand the mode of HEV transmission between animals and humans in the Baltic States region.

Satisfaction with organizational aspects of health care provision among Lithuanian physicians.

PubMed

Kairys, Jonas; Zebiene, Egle; Sapoka, Virginijus; Zokas, Ignas

2008-03-01

Physician satisfaction is considered an important factor influencing quality of health care provision, patient compliance, and costs to health care systems. Dissatisfaction leads to an increase in turnover of physicians and early retirement, which has a negative impact on continuity and quality of health care. Physician dissatisfaction with certain aspects of health care provision may also help to identify potential weaknesses in satisfactory functioning of health care systems. The aim of the current research project is to study the satisfaction with different organizational aspects of health care provision in Lithuania as judged by a selection of physicians. The study was conducted in Lithuania in June 2004. Physicians in randomly selected health care centers were invited to take part in the survey, 505 primary and secondary care physicians were interviewed by external interviewers during the study period. Physicians were asked to express their satisfaction on items presented in a questionnaire. The questionnaire consisted of 22 questions, evaluating different aspects of health care services - working conditions, workload, financial remuneration, organization of health care infrastructure and availability of laboratory services. Answers were presented by the 5 point Likert type scale, ranging from "very satisfied" (5) to "very dissatisfied" (1). Physicians who were most satisfied with their working conditions were working in private primary health care practices (91.1% satisfied or very satisfied), as compared with 54% of physicians working in state-owned primary care institutions and 49.7% in hospitals. Physicians working in cities and regional centers or towns were more satisfied with organizational aspects of health care services than physicians working in rural health care centers. Satisfaction with their financial remuneration showed that 74% of respondents stated they were "dissatisfied" or "very dissatisfied". While asked about potential deficiencies in their health care institutions, the most important identified by respondents in all localities was a perceived lack of financial support for these institutions. There is a significant difference in the perception of physicians in private and state health care institutions with regard to financial remuneration as well as availability of laboratory diagnostic and treatment equipment and working conditions. Based on the study findings, possibilities to increase Primary Care financing should be considered in order to improve the quality of the delivery of health care services as well as retain physicians within the health care system. Results of this study demonstrate a need of further research to quantify what could be reasonably expected from diagnostic and investigative resources to support health care in Lithuania in current economic situation.

Cartographic Mapping and Travel Burden to Assess and Develop Strategies to Improve Minority Access to National Cancer Clinical Trials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bruner, Deborah Watkins, E-mail: deborah.w.bruner@emory.edu; Pugh, Stephanie L.; Yeager, Katherine A.

Purpose: To assess how accrual to clinical trials is related to US minority population density relative to clinical trial site location and distance traveled to Radiation Therapy Oncology Group (RTOG) clinical trial sites. Methods and Materials: Data included member site address and ZIP codes, patient accrual, and patient race or ethnicity and ZIP code. Geographic Information System maps were developed for overall, Latino, and African American accrual to trials by population density. The Kruskal-Wallis test was used to assess differences in distance traveled by site, type of trial, and race or ethnicity. Results: From 2006 to 2009, 6168 patients enrolledmore » on RTOG trials. The RTOG US site distribution is generally concordant with overall population density. Sites with highest accrual are located throughout the United States and parts of Canada and do not cluster, nor does highest minority accrual cluster in areas of highest US minority population density. Of the 4913 US patients with complete data, patients traveled a median of 11.6 miles to participate in clinical trials. Whites traveled statistically longer distances (12.9 miles; P<.0001) to participate, followed by Latinos (8.22 miles) and African Americans (5.85 miles). Patients were willing to drive longer distances to academic sites than community sites, and there was a trend toward significantly longer median travel for therapeutic versus cancer control or metastatic trials. Conclusions: Location matters, but only to a degree, for minority compared with nonminority participation in clinical trials. Geographic Information System tools help identify gaps in geographic access and travel burden for clinical trials participation. Strategies that emerged using these tools are discussed.« less

Evaluation of European coeliac disease risk variants in a north Indian population

PubMed Central

Senapati, Sabyasachi; Gutierrez-Achury, Javier; Sood, Ajit; Midha, Vandana; Szperl, Agata; Romanos, Jihane; Zhernakova, Alexandra; Franke, Lude; Alonso, Santos; Thelma, B K; Wijmenga, Cisca; Trynka, Gosia

2015-01-01

Studies in European populations have contributed to a better understanding of the genetics of complex diseases, for example, in coeliac disease (CeD), studies of over 23 000 European samples have reported association to the HLA locus and another 39 loci. However, these associations have not been evaluated in detail in other ethnicities. We sought to better understand how disease-associated loci that have been mapped in Europeans translate to a disease risk for a population with a different ethnic background. We therefore performed a validation of European risk loci for CeD in 497 cases and 736 controls of north Indian origin. Using a dense-genotyping platform (Immunochip), we confirmed the strong association to the HLA region (rs2854275, P=8.2 × 10−49). Three loci showed suggestive association (rs4948256, P=9.3 × 10−7, rs4758538, P=8.6 × 10−5 and rs17080877, P=2.7 × 10−5). We directly replicated five previously reported European variants (P<0.05; mapping to loci harbouring FASLG/TNFSF18, SCHIP1/IL12A, PFKFB3/PRKCQ, ZMIZ1 and ICOSLG). Using a transferability test, we further confirmed association at PFKFB3/PRKCQ (rs2387397, P=2.8 × 10−4) and PTPRK/THEMIS (rs55743914, P=3.4 × 10−4). The north Indian population has a higher degree of consanguinity than Europeans and we therefore explored the role of recessively acting variants, which replicated the HLA locus (rs9271850, P=3.7 × 10−23) and suggested a role of additional four loci. To our knowledge, this is the first replication study of CeD variants in a non-European population. PMID:25052311

Changing livestock vaccination policy alters the epidemiology of human anthrax, Georgia, 2000-2013.

PubMed

Kracalik, Ian; Malania, Lile; Broladze, Mariam; Navdarashvili, Archil; Imnadze, Paata; Ryan, Sadie J; Blackburn, Jason K

2017-11-01

Anthrax is a widely spread zoonotic disease found on nearly every continent. To control the disease in humans and animals, annual livestock vaccination is recommended. However, in 2007, the country of Georgia ended its policy of compulsory annual livestock anthrax vaccination. Our objective was to assess how the epidemiology of human anthrax has evolved from 2000-2013 in Georgia, in the wake of this cessation. We used passive surveillance data on epidemiological surveys of human anthrax case patients. Risk factors and rates of self-reported sources of infection were compared, before and after the change in livestock vaccination policy. We mapped ethnicity-adjusted incidence during the two periods and assessed changes in the spatial pattern of risk. The overall risk of human anthrax increased >5-fold, from 0.7 cases per 100,000 in 2000 to 3.7 cases per 100,000 by 2013. Ethnic disparities in risk became pronounced; from 2000 to 2013, incidence increased >60-fold in Azerbaijanis from 0.35 to 21.1 cases/100,000 Azerbaijanis compared to 0.61 to 1.9 cases/100,000 among ethnic Georgians. Food-borne exposures from purchasing meat increased from 11% in 2000-2006 to 21% in 2007-2013. Spatial analyses revealed a shift from a random pattern of reporting pre-policy change to clustering among district municipalities following the change in policy. Our findings indicate there were unintended human health consequences associated with changing livestock vaccination policy. Following a reduction in the immunizations administered, there was a major shift in the epidemiology of human anthrax in Georgia. Current infection risk is now highest among ethnic minorities. Increased reporting among individuals uncharacteristically at risk for anthrax from foodborne exposures suggests spillover from modes of agricultural production. Given the importance of human-livestock health linkages, careful evaluations of policy need to be undertaken before changes to animal vaccination are made. Copyright © 2017 Elsevier Ltd. All rights reserved.

Using GIS and secondary data to target diabetes-related public health efforts.

PubMed

Curtis, Amy B; Kothari, Catherine; Paul, Rajib; Connors, Elyse

2013-01-01

To efficiently help communities prevent and manage diabetes, health departments need to be able to target populations with high risk but low resources. To aid in this process, we mapped county-level diabetes-related rates and resources/use using publicly available secondary data to identify Michigan counties with high diabetes prevalence and low or no medical and/or community resources. We collected county-level diabetes-related rates and resources from Web-based sources and mapped them using geographic information systems (GIS) software. Data included age-adjusted county diabetes rates, diabetes-related medical resource and resource use (i.e., the number of endocrinologists and percentage of Medicare patients with diabetes who received hemoglobin A1c testing in the past year), community resources (i.e., the number of certified diabetes self-management education and diabetes support groups), as well as population estimates and demographics (e.g., rural residence, education, poverty, and race/ethnicity). We created GIS maps highlighting areas that had higher-than-median rates of disease and lower-than-median resources. We also conducted linear, logistic, and Poisson regression analyses to confirm GIS findings. There were clear regional trends in resource distribution across Michigan. The 15 counties in the Upper Peninsula were lacking in medical resources but higher in community resources compared with the 68 counties in the Lower Peninsula. There was little apparent association between need (diabetes prevalence) and diabetes-related resources/use. Specific counties with high diabetes prevalence and low resources were easily identified using GIS mapping. Using public data and mapping tools identified diabetes health-service shortage areas for targeted public health programming.

Genetic epidemiology of pharmacogenetic variants in South East Asian Malays using whole-genome sequences.

PubMed

Sivadas, A; Salleh, M Z; Teh, L K; Scaria, V

2017-10-01

Expanding the scope of pharmacogenomic research by including multiple global populations is integral to building robust evidence for its clinical translation. Deep whole-genome sequencing of diverse ethnic populations provides a unique opportunity to study rare and common pharmacogenomic markers that often vary in frequency across populations. In this study, we aim to build a diverse map of pharmacogenetic variants in South East Asian (SEA) Malay population using deep whole-genome sequences of 100 healthy SEA Malay individuals. We investigated the allelic diversity of potentially deleterious pharmacogenomic variants in SEA Malay population. Our analysis revealed 227 common and 466 rare potentially functional single nucleotide variants (SNVs) in 437 pharmacogenomic genes involved in drug metabolism, transport and target genes, including 74 novel variants. This study has created one of the most comprehensive maps of pharmacogenetic markers in any population from whole genomes and will hugely benefit pharmacogenomic investigations and drug dosage recommendations in SEA Malays.

Genetic identification of a common collagen disease in Puerto Ricans via identity-by-descent mapping in a health system

PubMed Central

Belbin, Gillian Morven; Odgis, Jacqueline; Sorokin, Elena P; Yee, Muh-Ching; Kohli, Sumita; Glicksberg, Benjamin S; Gignoux, Christopher R; Wojcik, Genevieve L; Van Vleck, Tielman; Jeff, Janina M; Linderman, Michael; Schurmann, Claudia; Ruderfer, Douglas; Cai, Xiaoqiang; Merkelson, Amanda; Justice, Anne E; Young, Kristin L; Graff, Misa; North, Kari E; Peters, Ulrike; James, Regina; Hindorff, Lucia; Kornreich, Ruth; Edelmann, Lisa; Gottesman, Omri; Stahl, Eli EA; Cho, Judy H; Loos, Ruth JF; Bottinger, Erwin P; Nadkarni, Girish N; Abul-Husn, Noura S

2017-01-01

Achieving confidence in the causality of a disease locus is a complex task that often requires supporting data from both statistical genetics and clinical genomics. Here we describe a combined approach to identify and characterize a genetic disorder that leverages distantly related patients in a health system and population-scale mapping. We utilize genomic data to uncover components of distant pedigrees, in the absence of recorded pedigree information, in the multi-ethnic BioMe biobank in New York City. By linking to medical records, we discover a locus associated with both elevated genetic relatedness and extreme short stature. We link the gene, COL27A1, with a little-known genetic disease, previously thought to be rare and recessive. We demonstrate that disease manifests in both heterozygotes and homozygotes, indicating a common collagen disorder impacting up to 2% of individuals of Puerto Rican ancestry, leading to a better understanding of the continuum of complex and Mendelian disease. PMID:28895531

A survey of the population genetic variation in the human kinome.

PubMed

Zhang, Wei; Catenacci, Daniel V T; Duan, Shiwei; Ratain, Mark J

2009-08-01

Protein kinases are key regulators of various biological processes, such as control of cell growth, metabolism, differentiation and apoptosis. Therefore, protein kinases have been an important class of targets for anticancer drugs. Health-related disparities such as differential drug response have been observed between human populations. A survey of the human kinases and their ligand genes for those containing population-specific genetic variants could provide new insights into the mechanisms of these health disparities and suggest novel targets for ethnicity-specific personalized medicine. Using the International HapMap Project genotypic data on single-nucleotide polymorphisms (SNPs), the protein kinase complement of the human genome (kinome) and some experimentally verified ligand genes were scanned for the existence of population-specific SNPs (eSNPs). In general, protein kinases were found to contain a much higher proportion of eSNPs than the whole genome background, indicating a stronger pressure for adaptation in individual populations. In contrast, the proportion of ligand genes containing eSNPs was not different from that of the whole genome background. Although with some important limitations, our results suggest that human kinases are more likely to be under recent positive selection than ligands. Our findings suggest that the health-related disparities associated with kinase signaling pathways are more likely to be driven by the genetic variation in the kinase genes than their cognate ligands. Illustrating the role of molecular evolution in the genetic variation of the human kinome could provide a promising route to understand the ethnic differences in cancer and facilitate the realization of ethnicity-based individualized medicine.

Patterns of population differentiation of candidate genes for cardiovascular disease

PubMed Central

Kullo, Iftikhar J; Ding, Keyue

2007-01-01

Background The basis for ethnic differences in cardiovascular disease (CVD) susceptibility is not fully understood. We investigated patterns of population differentiation (FST) of a set of genes in etiologic pathways of CVD among 3 ethnic groups: Yoruba in Nigeria (YRI), Utah residents with European ancestry (CEU), and Han Chinese (CHB) + Japanese (JPT). We identified 37 pathways implicated in CVD based on the PANTHER classification and 416 genes in these pathways were further studied; these genes belonged to 6 biological processes (apoptosis, blood circulation and gas exchange, blood clotting, homeostasis, immune response, and lipoprotein metabolism). Genotype data were obtained from the HapMap database. Results We calculated FST for 15,559 common SNPs (minor allele frequency ≥ 0.10 in at least one population) in genes that co-segregated among the populations, as well as an average-weighted FST for each gene. SNPs were classified as putatively functional (non-synonymous and untranslated regions) or non-functional (intronic and synonymous sites). Mean FST values for common putatively functional variants were significantly higher than FST values for nonfunctional variants. A significant variation in FST was also seen based on biological processes; the processes of 'apoptosis' and 'lipoprotein metabolism' showed an excess of genes with high FST. Thus, putative functional SNPs in genes in etiologic pathways for CVD show greater population differentiation than non-functional SNPs and a significant variance of FST values was noted among pairwise population comparisons for different biological processes. Conclusion These results suggest a possible basis for varying susceptibility to CVD among ethnic groups. PMID:17626638

Tay-Sachs disease preconception screening in Australia: self-knowledge of being an Ashkenazi Jew predicts carrier state better than does ancestral origin, although there is an increased risk for c.1421 + 1G > C mutation in individuals with South African heritage.

PubMed

Lew, Raelia; Burnett, Leslie; Proos, Anné

2011-12-01

The Australasian Community Genetics Program provided a preconception screening for Tay-Sachs disease (TSD) to 4,105 Jewish high school students in Sydney and Melbourne over the 12-year period 1995-2007. By correlating the frequencies of mutant HEXA, MIM *606869 (gene map locus 15q23-q24) alleles with subjects' nominated ethnicity (Ashkenazi/Sephardi/Mixed) and grandparental birthplaces, we established that Ashkenazi ethnicity is a better predictor of TSD carrier status than grandparental ancestral origins. Screening self-identified Ashkenazi subjects detected 95% of TSD carriers (carrier frequency 1:25). Having mixed Ashkenazi and non-Ashkenazi heritage reduced the carrier frequency (1:97). South African heritage conveyed a fourfold risk of c.1421 + 1G > C mutation compared with other AJ subjects (odds ratio (OR), 4.19; 95% confidence interval (CI), 1.83-9.62, p = 0.001), but this was the only specific case of ancestral origin improving diagnostic sensitivity over that based on determining Ashkenazi ethnicity. Carriers of c.1278insTATC mutations were more likely to have heritage from Western Europe (OR, 1.65 (95% CI, 1.04-2.60), p = 0.032) and South Eastern Europe (OR, 1.77 (95% CI, 1.14-2.73), p = 0.010). However, heritage from specific European countries investigated did not significantly alter the overall odds of TSD carrier status.

Economic downturn results in tick-borne disease upsurge.

PubMed

Godfrey, Elinor R; Randolph, Sarah E

2011-03-15

The emergence of zoonoses is due both to changes in human activities and to changes in their natural wildlife cycles. One of the most significant vector-borne zoonoses in Europe, tick-borne encephalitis (TBE), doubled in incidence in 1993, largely as a consequence of the socio-economic transition from communism to capitalism and associated environmental changes. To test the effect of the current economic recession, unemployment in 2009 and various socio-economic indices were compared to weather indices (derived from principal component analyses) as predictors for the change in TBE case numbers in 2009 relative to 2004-08, for 14 European countries. Greatest increases in TBE incidence occurred in Latvia, Lithuania and Poland (91, 79 and 45%, respectively). The weather was rejected as an explanatory variable. Indicators of high background levels of poverty, e.g. percent of household expenditure on food, were significant predictors. The increase in unemployment in 2009 relative to 2008 together with 'in-work risk of poverty' is the only case in which a multivariate model has a second significant term. Background socio-economic conditions determine susceptibility to risk of TBE, while increased unemployment triggered a sudden increase in risk. Mechanisms behind this result may include reduced resistance to infection through stress; reduced uptake of costly vaccination; and more exposure of people to infected ticks in their forest habitat as they make greater use of wild forest foods, especially in those countries, Lithuania and Poland, with major marketing opportunities in such products. Recognition of these risk factors could allow more effective protection through education and a vaccination programme targeted at the economically most vulnerable.

Response of deciduous trees spring phenology to recent and projected climate change in Central Lithuania

NASA Astrophysics Data System (ADS)

Juknys, Romualdas; Kanapickas, Arvydas; Šveikauskaitė, Irma; Sujetovienė, Gintarė

2016-10-01

The analysis of long-term time series of spring phenology for different deciduous trees species has shown that leaf unfolding for all the investigated species is the most sensitive to temperatures in March and April and illustrates that forcing temperature is the main driver of the advancement of leaf unfolding. Available chilling amount has increased by 22.5 % over the last 90 years, indicating that in the investigated geographical region there is no threat of chilling shortage. The projection of climatic parameters for Central Lithuania on the basis of three global circulation models has shown that under the optimistic climate change scenario (RCP 2.6) the mean temperature tends to increase by 1.28 °C and under the pessimistic scenario (RCP 8.5) by 5.03 °C until the end of the current century. Recently, different statistical models are used not only to analyze but also to project the changes in spring phenology. Our study has shown that when the data of long-term phenological observations are available, multiple regression models are suitable for the projection of the advancement of leaf unfolding under the changing climate. According to the RCP 8.5 scenario, the projected advancement in leaf unfolding for early-season species birch consists of almost 15 days as an average of all three used GSMs. Markedly less response to the projected far future (2071-2100), climate change is foreseen for other investigated climax species: -9 days for lime, 10 days for oak, and 11 days for maple.

Response of deciduous trees spring phenology to recent and projected climate change in Central Lithuania.

PubMed

Juknys, Romualdas; Kanapickas, Arvydas; Šveikauskaitė, Irma; Sujetovienė, Gintarė

2016-10-01

The analysis of long-term time series of spring phenology for different deciduous trees species has shown that leaf unfolding for all the investigated species is the most sensitive to temperatures in March and April and illustrates that forcing temperature is the main driver of the advancement of leaf unfolding. Available chilling amount has increased by 22.5 % over the last 90 years, indicating that in the investigated geographical region there is no threat of chilling shortage. The projection of climatic parameters for Central Lithuania on the basis of three global circulation models has shown that under the optimistic climate change scenario (RCP 2.6) the mean temperature tends to increase by 1.28 °C and under the pessimistic scenario (RCP 8.5) by 5.03 °C until the end of the current century. Recently, different statistical models are used not only to analyze but also to project the changes in spring phenology. Our study has shown that when the data of long-term phenological observations are available, multiple regression models are suitable for the projection of the advancement of leaf unfolding under the changing climate. According to the RCP 8.5 scenario, the projected advancement in leaf unfolding for early-season species birch consists of almost 15 days as an average of all three used GSMs. Markedly less response to the projected far future (2071-2100), climate change is foreseen for other investigated climax species: -9 days for lime, 10 days for oak, and 11 days for maple.

Socioeconomic inequalities in all-cause mortality in the Czech Republic, Russia, Poland and Lithuania in the 2000s: findings from the HAPIEE Study.

PubMed

Vandenheede, Hadewijch; Vikhireva, Olga; Pikhart, Hynek; Kubinova, Ruzena; Malyutina, Sofia; Pajak, Andrzej; Tamosiunas, Abdonas; Peasey, Anne; Simonova, Galina; Topor-Madry, Roman; Marmot, Michael; Bobak, Martin

2014-04-01

Relatively large socioeconomic inequalities in health and mortality have been observed in Central and Eastern Europe (CEE) and the former Soviet Union (FSU). Yet comparative data are sparse and virtually all studies include only education. The aim of this study is to quantify and compare socioeconomic inequalities in all-cause mortality during the 2000s in urban population samples from four CEE/FSU countries, by three different measures of socioeconomic position (SEP) (education, difficulty buying food and household amenities), reflecting different aspects of SEP. Data from the prospective population-based HAPIEE (Health, Alcohol, and Psychosocial factors in Eastern Europe) study were used. The baseline survey (2002-2005) included 16 812 men and 19 180 women aged 45-69 years in Novosibirsk (Russia), Krakow (Poland), Kaunas (Lithuania) and seven Czech towns. Deaths in the cohorts were identified through mortality registers. Data were analysed by direct standardisation and Cox regression, quantifying absolute and relative SEP differences. Mortality inequalities by the three SEP indicators were observed in all samples. The magnitude of inequalities varied according to gender, country and SEP measure. As expected, given the high mortality rates in Russian men, largest absolute inequalities were found among Russian men (educational slope index of inequality was 19.4 per 1000 person-years). Largest relative inequalities were observed in Czech men and Lithuanian subjects. Disadvantage by all three SEP measures remained strongly associated with increased mortality after adjusting for the other SEP indicators. The results emphasise the importance of all SEP measures for understanding mortality inequalities in CEE/FSU.

Methods of Implementation of Evidence-Based Stroke Care in Europe: European Implementation Score Collaboration.

PubMed

Di Carlo, Antonio; Pezzella, Francesca Romana; Fraser, Alec; Bovis, Francesca; Baeza, Juan; McKevitt, Chris; Boaz, Annette; Heuschmann, Peter; Wolfe, Charles D A; Inzitari, Domenico

2015-08-01

Differences in stroke care and outcomes reported in Europe may reflect different degrees of implementation of evidence-based interventions. We evaluated strategies for implementing research evidence into stroke care in 10 European countries. A questionnaire was developed and administered through face-to-face interviews with key informants. Implementation strategies were investigated considering 3 levels (macro, meso, and micro, eg, policy, organization, patients/professionals) identified by the framing analysis, and different settings (primary, hospital, and specialist) of stroke care. Similarities and differences among countries were evaluated using the categorical principal components analysis. Implementation methods reported by ≥7 countries included nonmandatory policies, public financial incentives, continuing professional education, distribution of educational material, educational meetings and campaigns, guidelines, opinion leaders', and stroke patients associations' activities. Audits were present in 6 countries at national level; national and regional regulations in 4 countries. Private financial incentives, reminders, and educational outreach visits were reported only in 2 countries. At national level, the first principal component of categorical principal components analysis separated England, France, Scotland, and Sweden, all with positive object scores, from the other countries. Belgium and Lithuania obtained the lowest scores. At regional level, England, France, Germany, Italy, and Sweden had positive scores in the first principal component, whereas Belgium, Lithuania, Poland, and Scotland showed negative scores. Spain was in an intermediate position. We developed a novel method to assess different domains of implementation in stroke care. Clear variations were observed among European countries. The new tool may be used elsewhere for future contributions. © 2015 American Heart Association, Inc.

Forensic anthropology and mortuary archaeology in Lithuania.

PubMed

Jankauskas, Rimantas

2009-12-01

Forensic anthropology (in Lithuania, as everywhere in Eastern Europe, traditionally considered as a narrower field--forensic osteology) has a long history, experience being gained both during exhumations of mass killings during the Second World War and the subsequent totalitarian regime, investigations of historical mass graves, identification of historical personalities and routine forensic work. Experts of this field (usually a branch of forensic medicine) routinely are solving "technical" questions of crime investigation, particularly identification of (usually dead) individuals. Practical implementation of the mission of forensic anthropology is not an easy task due to interdisciplinary character of the field. On one hand, physical anthropology has in its disposition numerous scientifically tested methods, however, their practical value in particular legal processes is limited. Reasons for these discrepancies can be related both to insufficient understanding of possibilities and limitations of forensic anthropology and archaeology by officials representing legal institutions that perform investigations, and sometimes too "academic" research, that is conducted at anthropological laboratories, when methods developed are not completely relevant to practical needs. Besides of answering to direct questions (number of individuals, sex, age, stature, population affinity, individual traits, evidence of violence), important humanitarian aspects--the individual's right for identity, the right of the relatives to know the fate of their beloved ones--should not be neglected. Practical use of other identification methods faces difficulties of their own (e.g., odontology--lack of regular dental registration system and compatible database). Two examples of forensic anthropological work of mass graves, even when the results were much influenced by the questions raised by investigators, can serve as an illustration of the above-mentioned issues.

Supply and demand for radiographers in Lithuania: a prognosis for 2012-2030.

PubMed

Vanckaviciene, Aurika; Starkiene, Liudvika; Macijauskiene, Jūrate

2014-07-01

This is the first ever study on the planning of the supply and demand for radiographers in Lithuania. The aim of this study was to analyze the supply and demand for radiographers in the labor market with respect to their number, structure, and services, and to provide a prognosis for the period of 2012-2030. Supply was calculated using two scenarios with differing duration of studies, annual student drop-out rates, rates of failure to start working, the annual number of new entrants into the labor market, and emigration rates. Annual mortality rates, the number of first-year students, and retirement rates were evaluated equally in both scenarios. Two projections of the demand for radiographers, based on the population's differing (by age and gender), need for outpatient radiology services, computed tomography, and magnetic resonance scans. Subsequently, the supply and demand scenarios were compared. Evaluation of the perspective supply and demand scenarios - which are the most probable - revealed a gap forming during the analyzed period, the predicted specialist shortage will reach 0.13 full-time equivalents per 10,000 population, and in 2030-0.37 full-time equivalents per 10,000 population. Considering the changes in education of radiographers, the socio-demographic characteristics of the staff, and the increasing need for radiographers' services, the supply of radiographers during the next two decades will be insufficient. To meet the forecasted demand for radiographers in the perspective scenario, the number of students choosing this specialty from 2013 on should increase by up to 30%. Copyright © 2014 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

Mental hygiene movement as a (r)evolutionary trend in public health in interwar Kaunas and Vilnius from 1918 to 1939.

PubMed

Žalnora, Aistis; Miežutavičiūtė, Vitalija

2016-01-01

The health care system of the interwar period is distinguished by its revolutionary attempts to overcome social diseases and social hardships in general. In the researches published after the Second World War, different and in some cases even contradicting ideas on mental hygiene and eugenics were mixed together and were associated - almost exclusively - with the Nazi's racist ideology, totalitarian, or authoritarian regimes. The assessments of social-medical policy of the interwar period in the Baltic region also became rather one-sided. Felder's recent study (1) gives the impression that changes in psychiatry in Lithuania were caused by the Nazi's eugenics as a single agent. However, there were other factors. One of the most significant ones was the mental hygiene movement that will be discussed in this paper. In this research we used descriptive and comparative methods. After the First World War, the problem of treatment of the mentally ill was a medical and a social issue that required a completely new approach both in Lithuania and in Vilnius. The most notable manifestation of such a new attitude in psychiatry was a mental hygiene movement. University scientists in Vilnius and Kaunas were discussing issues of mental hygiene. The mental hygiene movement of the early 20th century played an important role in the later development in psychiatry and medical sciences. The ideas published by the medical doctors in Kaunas and Vilnius were partly characteristic of the interwar period, although some of them went far ahead of their times.

Mental hygiene movement as a (r)evolutionary trend in public health in interwar Kaunas and Vilnius from 1918 to 1939

PubMed Central

Žalnora, Aistis; Miežutavičiūtė, Vitalija

2016-01-01

Objective. The health care system of the interwar period is distinguished by its revolutionary attempts to overcome social diseases and social hardships in general. In the researches published after the Second World War, different and in some cases even contradicting ideas on mental hygiene and eugenics were mixed together and were associated – almost exclusively – with the Nazi’s racist ideology, totalitarian, or authoritarian regimes. The assessments of social-medical policy of the interwar period in the Baltic region also became rather one-sided. Felder’s recent study (1) gives the impression that changes in psychiatry in Lithuania were caused by the Nazi’s eugenics as a single agent. However, there were other factors. One of the most significant ones was the mental hygiene movement that will be discussed in this paper. Methods. In this research we used descriptive and comparative methods. Results. After the First World War, the problem of treatment of the mentally ill was a medical and a social issue that required a completely new approach both in Lithuania and in Vilnius. The most notable manifestation of such a new attitude in psychiatry was a mental hygiene movement. University scientists in Vilnius and Kaunas were discussing issues of mental hygiene. Conclusions. The mental hygiene movement of the early 20th century played an important role in the later development in psychiatry and medical sciences. The ideas published by the medical doctors in Kaunas and Vilnius were partly characteristic of the interwar period, although some of them went far ahead of their times. PMID:28356806

Associations between self-rated health and psychosocial conditions, lifestyle factors and health resources among hospital nurses in Lithuania.

PubMed

Malinauskiene, Vilija; Leisyte, Palmira; Romualdas, Malinauskas; Kirtiklyte, Kristina

2011-11-01

The aim of our study was to investigate the association between self-rated health and psychosocial factors at work and everyday life (job demands, job control, social support, workplace bullying, life-threatening events); health behaviours (smoking, alcohol, being overweight, obesity, low physical activity); mental distress; job satisfaction; and sense of coherence in a representative sample of Lithuanian hospitals' internal medicine department nurses. Recent trends to extend the retirement age in many countries of the European Union challenge future public health. Nurses are exposed to a broad variety of adverse psychosocial factors at work and in every day life that affect their health perception. As the retirement age in Lithuania is to be extended to 65 years for women, research on the associations of poor self-rated health with related factors is important. A cross-sectional study was carried out in the period 2005-2006 using the representative sample of Lithuanian hospitals' internal medicine department nurses. Data were collected from 748 nurses using questionnaire (response rate 53·9%). About 60·4% of nurses rated their health negatively. In the fully adjusted model age, high job demands, low job control, low social support at work, life-threatening events, low physical activity, being overweight, obesity, mental distress, job dissatisfaction and weak sense of coherence were associated with negative self-rated health. Preventive strategies against adverse psychosocial working conditions of nurses should be implemented in the Lithuanian hospitals. © 2011 The Authors. Journal of Advanced Nursing © 2011 Blackwell Publishing Ltd.

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium

PubMed Central

Lu, Yingchang; Justice, Anne E.; Mudgal, Poorva; Liu, Ching-Ti; Young, Kristin; Feitosa, Mary F.; Rand, Kristin; Dimitrov, Latchezar; Duan, Qing; Guo, Xiuqing; Lange, Leslie A.; Nalls, Michael A.; Okut, Hayrettin; Tayo, Bamidele O.; Vedantam, Sailaja; Bradfield, Jonathan P.; Chen, Guanjie; Chesi, Alessandra; Irvin, Marguerite R.; Padhukasahasram, Badri; Zheng, Wei; Allison, Matthew A.; Ambrosone, Christine B.; Bandera, Elisa V.; Berndt, Sonja I.; Blot, William J.; Bottinger, Erwin P.; Carpten, John; Chanock, Stephen J.; Chen, Yii-Der Ida; Conti, David V.; Cooper, Richard S.; Fornage, Myriam; Freedman, Barry I.; Garcia, Melissa; Goodman, Phyllis J.; Hsu, Yu-Han H.; Hu, Jennifer; Huff, Chad D.; Ingles, Sue A.; John, Esther M.; Kittles, Rick; Klein, Eric; Li, Jin; McKnight, Barbara; Nayak, Uma; Nemesure, Barbara; Olshan, Andrew; Salako, Babatunde; Sanderson, Maureen; Shao, Yaming; Siscovick, David S.; Stanford, Janet L.; Strom, Sara S.; Witte, John S.; Yao, Jie; Zhu, Xiaofeng; Ziegler, Regina G.; Zonderman, Alan B.; Ambs, Stefan; Cushman, Mary; Faul, Jessica D.; Hakonarson, Hakon; Levin, Albert M.; Nathanson, Katherine L.; Weir, David R.; Zhi, Degui; Arnett, Donna K.; Kardia, Sharon L. R.; Oloapde, Olufunmilayo I.; Rao, D. C.; Williams, L. Keoki; Becker, Diane M.; Borecki, Ingrid B.; Evans, Michele K.; Harris, Tamara B.; Hirschhorn, Joel N.; Psaty, Bruce M.; Wilson, James G.; Bowden, Donald W.; Cupples, L. Adrienne; Haiman, Christopher A.; Loos, Ruth J. F.; North, Kari E.

2017-01-01

Genome-wide association studies (GWAS) have identified >300 loci associated with measures of adiposity including body mass index (BMI) and waist-to-hip ratio (adjusted for BMI, WHRadjBMI), but few have been identified through screening of the African ancestry genomes. We performed large scale meta-analyses and replications in up to 52,895 individuals for BMI and up to 23,095 individuals for WHRadjBMI from the African Ancestry Anthropometry Genetics Consortium (AAAGC) using 1000 Genomes phase 1 imputed GWAS to improve coverage of both common and low frequency variants in the low linkage disequilibrium African ancestry genomes. In the sex-combined analyses, we identified one novel locus (TCF7L2/HABP2) for WHRadjBMI and eight previously established loci at P < 5×10−8: seven for BMI, and one for WHRadjBMI in African ancestry individuals. An additional novel locus (SPRYD7/DLEU2) was identified for WHRadjBMI when combined with European GWAS. In the sex-stratified analyses, we identified three novel loci for BMI (INTS10/LPL and MLC1 in men, IRX4/IRX2 in women) and four for WHRadjBMI (SSX2IP, CASC8, PDE3B and ZDHHC1/HSD11B2 in women) in individuals of African ancestry or both African and European ancestry. For four of the novel variants, the minor allele frequency was low (<5%). In the trans-ethnic fine mapping of 47 BMI loci and 27 WHRadjBMI loci that were locus-wide significant (P < 0.05 adjusted for effective number of variants per locus) from the African ancestry sex-combined and sex-stratified analyses, 26 BMI loci and 17 WHRadjBMI loci contained ≤ 20 variants in the credible sets that jointly account for 99% posterior probability of driving the associations. The lead variants in 13 of these loci had a high probability of being causal. As compared to our previous HapMap imputed GWAS for BMI and WHRadjBMI including up to 71,412 and 27,350 African ancestry individuals, respectively, our results suggest that 1000 Genomes imputation showed modest improvement in identifying GWAS loci including low frequency variants. Trans-ethnic meta-analyses further improved fine mapping of putative causal variants in loci shared between the African and European ancestry populations. PMID:28430825

Epidemiological Study of Orofacial Clefts among Population of Eastern Slovakia during the Period 1996-2013.

PubMed

Pacáková, Diana; Zábavníková, Marianna; Miklošová, Mária; Kúkeľová, Diana; Dankovčík, Róbert

2016-06-01

Over the past 18 years, according to data from the Clinic of Plastic and Reconstructive Surgery, L. Pasteur University Hospital, there have been 493 cases of orofacial clefts (OC) reported in the area of Eastern Slovakia. The aim of this study was to map the occurrence of orofacial clefts reported in the area of Eastern Slovakia during the years 1996-2013. Also, we compared the occurrence of different types of clefts between the groups in relation to gender and ethnicity. The statistical analysis shows relationship between variables of location and gender and gender differences in the occurrence of various types of clefts. Moreover, in comparison with another study which analyzed the years 1985-2000 (1.29/10(3) live births), there was an increase in the incidence (1.42/10(3) live births) of OC in Eastern Slovakia. Our findings seem contradictive to similar studies which discuss ethnic differences in relation to OC. We recognize the relatively high occurrence of OC in Eastern Slovakia, and we link this phenomenon to several extrinsic factors, in particular socioeconomic status and embryotoxic factors. Copyright© by the National Institute of Public Health, Prague 2015.

European multiple sclerosis risk variants in the south Asian population.

PubMed

Pandit, Lekha; Ban, Maria; Beecham, Ashley Harris; McCauley, Jacob L; Sawcer, Stephen; D'Cunha, Anitha; Malli, Chaitra; Malik, Omar

2016-10-01

In less than a decade, genomewide association studies have identified over 100 single-nucleotide variants that are associated with increased risk of developing multiple sclerosis. However, since these studies have focused almost exclusively on European populations, it is unclear what role these variants might play in determining risk in other ethnic groups. To assess the effects of European multiple sclerosis-associated risk variants in the south Asian population. Using a combination of chip-based genotyping and next-generation sequencing, we have assessed 109 European-associated variants in a total of 270 cases and 555 controls from the south Asian population. We found that two-thirds of the tested variants (72/109) showed over representation of the European risk allele in south Asian cases (p < 0.0003). In the rest of the Immunochip array, the most associated variant was rs7318477 which maps close to TNFSF13B, the gene for the B-cell-related protein BAFF. Our data indicate substantial overlap in genetic risk architecture between Europeans and south Asians and suggest that the aetiology of the disease may be largely independent of ethnicity. © The Author(s), 2016.

Sequence-length variation of mtDNA HVS-I C-stretch in Chinese ethnic groups.

PubMed

Chen, Feng; Dang, Yong-hui; Yan, Chun-xia; Liu, Yan-ling; Deng, Ya-jun; Fulton, David J R; Chen, Teng

2009-10-01

The purpose of this study was to investigate mitochondrial DNA (mtDNA) hypervariable segment-I (HVS-I) C-stretch variations and explore the significance of these variations in forensic and population genetics studies. The C-stretch sequence variation was studied in 919 unrelated individuals from 8 Chinese ethnic groups using both direct and clone sequencing approaches. Thirty eight C-stretch haplotypes were identified, and some novel and population specific haplotypes were also detected. The C-stretch genetic diversity (GD) values were relatively high, and probability (P) values were low. Additionally, C-stretch length heteroplasmy was observed in approximately 9% of individuals studied. There was a significant correlation (r=-0.961, P<0.01) between the expansion of the cytosine sequence length in the C-stretch of HVS-I and a reduction in the number of upstream adenines. These results indicate that the C-stretch could be a useful genetic maker in forensic identification of Chinese populations. The results from the Fst and dA genetic distance matrix, neighbor-joining tree, and principal component map also suggest that C-stretch could be used as a reliable genetic marker in population genetics.

Emancipatory actions displayed by multi-ethnic women: "Regaining control of my health care".

PubMed

Alexander, Ivy M

2010-11-01

Despite the recognized importance of patient involvement in primary care interactions, little information describing women's needs and expectations for these interactions is available. This participatory action study was based in Critical Action Theory and designed to describe any emancipatory interests that surfaced when eight ethnically diverse women examined their interactions with primary care nurse practitioners (PCNPs) over the course of five successive focus group meetings. Focus group meeting transcripts, field notes, interaction notations, seating maps, and first impression summaries. Participants wanted to learn how to "stand up" for themselves in primary care interactions. They believed this could be accomplished by developing a positive sense of self-esteem. Ultimately, they identified the right way to "talk back" to clinicians and created a method for regaining control of their own health care and maintaining equality in interactions with primary care clinicians. Nurse practitioners working in the primary setting are especially well situated to support self-management and foster patient participation by women as they live with chronic disease, engage in health promotion activities, and deal with common symptomatic problems for themselves and their families. ©2010 The Author Journal compilation ©2010 American Academy of Nurse Practitioners.

An examination of biracial college youths' family ethnic socialization, ethnic identity, and adjustment: do self-identification labels and university context matter?

PubMed

Brittian, Aerika S; Umaña-Taylor, Adriana J; Derlan, Chelsea L

2013-04-01

This study examined family ethnic socialization, ethnic identity, and adjustment among Latino/White and Asian/White biracial college students (n = 507), with special attention to how ethnic self-identification and university ethnic composition informed the ethnic identity process. Findings indicated that family ethnic socialization was positively related to participants' ethnic identity exploration and resolution, but not ethnic identity affirmation. Furthermore, ethnic identity resolution and affirmation were associated with higher self-acceptance and self-esteem, and lower depressive symptoms. Importantly, university ethnic composition moderated the association between ethnic identity resolution and anxiety, such that resolution promoted adjustment in contexts that were relatively more ethnically diverse. University ethnic composition also moderated the association between ethnic identity affirmation and both self-esteem and self-acceptance, such that affirmation was associated with better adjustment but only in schools that were less ethnically diverse.

An Examination of Biracial College Youths’ Family Ethnic Socialization, Ethnic Identity, and Adjustment: Do Self-Identification Labels and University Context Matter?

PubMed Central

Brittian, Aerika S.; Umaña-Taylor, Adriana J.; Derlan, Chelsea L.

2014-01-01

This study examined family ethnic socialization, ethnic identity, and adjustment among Latino/White and Asian/White biracial college students (n = 507), with special attention to how ethnic self-identification and university ethnic composition informed the ethnic identity process. Findings indicated that family ethnic socialization was positively related to participants’ ethnic identity exploration and resolution, but not ethnic identity affirmation. Furthermore, ethnic identity resolution and affirmation were associated with higher self-acceptance and self-esteem, and lower depressive symptoms. Importantly, university ethnic composition moderated the association between ethnic identity resolution and anxiety, such that resolution promoted adjustment in contexts that were relatively more ethnically diverse. University ethnic composition also moderated the association between ethnic identity affirmation and both self-esteem and self-acceptance, such that affirmation was associated with better adjustment but only in schools that were less ethnically diverse. PMID:22905967

Health Disparities in Veterans: A Map of the Evidence.

PubMed

Kondo, Karli; Low, Allison; Everson, Teresa; Gordon, Christine D; Veazie, Stephanie; Lozier, Crystal C; Freeman, Michele; Motu'apuaka, Makalapua; Mendelson, Aaron; Friesen, Mark; Paynter, Robin; Friesen, Caroline; Anderson, Johanna; Boundy, Erin; Saha, Somnath; Quiñones, Ana; Kansagara, Devan

2017-09-01

Goals for improving the quality of care for all Veterans and eliminating health disparities are outlined in the Veterans Health Administration Blueprint for Excellence, but the degree to which disparities in utilization, health outcomes, and quality of care affect Veterans is not well understood. To characterize the research on health care disparities in the Veterans Health Administration by means of a map of the evidence. We conducted a systematic search for research studies published from 2006 to February 2016 in MEDLINE and other data sources. We included studies of Veteran populations that examined disparities in 3 outcome categories: utilization, quality of health care, and patient health. We abstracted data on study design, setting, population, clinical area, outcomes, mediators, and presence of disparity for each outcome category. We grouped the data by population characteristics including race, disability status, mental illness, demographics (age, era of service, rural location, and distance from care), sex identity, socioeconomic status, and homelessness, and created maps illustrating the evidence. We reviewed 4249 citations and abstracted data from 351 studies which met inclusion criteria. Studies examining disparities by race/ethnicity comprised by far the vast majority of the literature, followed by studies examining disparities by sex, and mental health condition. Very few studies examined disparities related to lesbian, gay, bisexual, or transgender identity or homelessness. Disparities findings vary widely by population and outcome. Our evidence maps provide a "lay of the land" and identify important gaps in knowledge about health disparities experienced by different Veteran populations.

Mapping the functional assessment of cancer therapy-breast (FACT-B) to the 5-level EuroQoL Group's 5-dimension questionnaire (EQ-5D-5L) utility index in a multi-ethnic Asian population.

PubMed

Cheung, Yin Bun; Luo, Nan; Ng, Raymond; Lee, Chun Fan

2014-12-12

To develop an algorithm for mapping the Functional Assessment of Cancer Therapy-Breast (FACT-B) to the 5-level EuroQoL Group's 5-dimension questionnaire (EQ-5D-5L) utility index. A survey of 238 breast cancer patients in Singapore was conducted. Models using various regression methods with or without recognizing the upper boundary of utility values at 1 were fitted to predict the EQ-5D-5L utility index based on the five subscale scores of the FACT-B. Data from a follow-up survey of these patients were used to validate the results. A model that maps the physical, emotional, functional well-being and the breast cancer concerns subscales of the FACT-B to the EQ-5D-5L utility index was derived. The social well-being subscale was not associated to the utility index. Although theoretical assumptions may not be valid, ordinary least square outperformed other regression methods. The mean predicted utility index within each performance status level at follow-up deviated from the observed mean less than the minimally important difference of EQ-5D for cancer patients. The mapping algorithm converts the FACT-B to the EQ-5D utility index. This enables oncologists, clinical researchers and policy makers to obtain a quantitative utility summary of a patient's health status when only the FACT-B is assessed.

Mexican American Children's Ethnic Identity, Understanding of Ethnic Prejudice, and Parental Ethnic Socialization.

ERIC Educational Resources Information Center

Quintana, Stephen M.; Vera, Elizabeth M.

1999-01-01

Interviews with 47 Mexican-American children in grades 2 and 6 and their parents revealed that parental ethnic socialization about ethnic discrimination was associated with children's development of ethnic knowledge. Children's understanding of ethnic prejudice was related to their ethnic knowledge but not their ethnic behaviors. Contains 24…

Menarche stories: reminiscences of college students from Lithuania, Malaysia, Sudan, and the United States.

PubMed

Chrisler, J C; Zittel, C B

1998-01-01

Women college students in four countries were invited to write the story of their first menstruation in as much detail as memory allowed. Stories were received from 26 Lithuanians, 27 Americans, 20 Malaysians, and 23 Sudanese. The stories were read and their contents analyzed for the presence or absence of information on such topics as emotional reaction, preparedness, sources of information about menstruation, changes in body image, and celebrations of this rite of passage. Similarities and differences among the groups are discussed, and passages from particularly interesting stories are quoted.

Lithuanian female physicists: Reality and plans for the future

NASA Astrophysics Data System (ADS)

Šatkovskienė, Dalia; Giriunienė, Ramutė; Ruželė, Živilė; Rutkunienė, Živilė

2013-03-01

Changes in the issue of women in physics in Lithuanian in the three years since the 3rd IUPAP International Conference on Women in Physics are discussed on the basis of statistics as well as an exploratory study recently conducted among women physicists. The situation has changed slowly since 2008. However, the study shows that women physicists more clearly understand the inequities and the need for changes, including an active European Union mainstreaming policy targeted to ensure gender equality in the sciences, which gives hope for accelerating changes. Continued plans for improving women physicists' situation in Lithuania are discussed.

Extensively Drug-Resistant Tuberculosis (XDR-TB) - A Potential Threat in Ireland

PubMed Central

Mc Laughlin, Anne Marie; O’Donnell, Rory A; Gibbons, Noel; Scully, Mary; O’Flangan, Darina; Keane, Joseph

2007-01-01

We describe a case of a 25 year old female from Lithuania who presented with a productive cough. Chest radiograph demonstrated an infiltrate in the left upper lobe and a cavitating lesion in the right middle lobe. Sensitivity testing of her sputum led to a diagnosis of extensively drug-resistant tuberculosis (XDR-TB). This is the first case in Ireland and highlights the need for physicians to be aware of the possibility of XDR-TB. Moreover it underlines the need for improvement in service provision in terms of a TB reference laboratory and TB clinics. PMID:19340317

Ethnic identities and lifestyles in a multi-ethnic cancer patient population.

PubMed

Gotay, Carolyn Cook; Holup, Joan

2004-09-01

This report examined ethnic identity in 367 recently diagnosed cancer patients in Hawai'i's primary ethnic groups: Japanese, Hawaiians, Europeans, and Filipinos. The study assessed ethnic self-identify; definitions of and participation in different ethnic lifestyles; and relationships between measures of ethnic self-identity, lifestyle, and other indicators of ethnic and cultural affiliations. Results indicated that medical record-based ethnic indicators were well linked to individual self-reports of family pedigree. Self-descriptors included non-standard terms such as "American" and "Local," and respondents reported following between five and six different ethnically-associated ways of life. Multivariate analysis indicated that ethnic self-identity made a unique contribution that went beyond standard ethnic and acculturative markers in explaining lifestyles. This study provides strong support for multiculturalism in this ethnically heterogeneous population.

Daily Intragroup Contact in Diverse Settings: Implications for Asian Adolescents' Ethnic Identity

PubMed Central

Yip, Tiffany; Douglass, Sara E.; Shelton, J. Nicole

2013-01-01

This study examined the daily-level association between contact with same-ethnic others and ethnic private regard among 132 Asian adolescents (mean age 14) attending 4 high schools ranging in ethnic composition diversity. The data suggest a positive daily-level association between contact with same-ethnic others and ethnic private regard for adolescents who were highly identified with their ethnic group and who attended predominantly White or ethnically heterogeneous schools. In addition, using time lag analyses, contact with same-ethnic others yesterday was positively related to ethnic private regard today, but ethnic private regard yesterday was unrelated to contact with same-ethnic others today, suggesting that adolescents' identity is responsive to their environments. The implications of these findings for the development of ethnic identity are discussed. PMID:23294295

Birds of an ethnic feather? Ethnic identity homophily among college-age friends.

PubMed

Syed, Moin; Juan, Mary Joyce D

2012-12-01

This study assessed the degree to which pairs of friends report similar levels of ethnic identity. College-age friends (n=107 pairs; N=214 overall) completed measures of ethnic identity exploration and commitment, identity synthesis, relationship closeness, and frequency of talking to friends and family about ethnicity-related issues. Participants were ethnically-diverse and constituted three types of dyads: both ethnic minorities (n=51), both White (n=24), or mixed ethnic minority and White (n=32). Overall, friends reported similar levels of ethnic identity exploration and commitment. The ethnic composition of the pair moderated similarity, with ethnic minority pairs showing greater similarity than the White and mixed pairs. Frequency of ethnicity-related discussions with friends and family, but not relationship closeness, mediated the observed similarity for ethnic minority pairs. These findings suggest a level of ethnic identity homophily between ethnic minority friends that can be explained by interactional mechanisms. Copyright © 2011 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

Role of ethnicity in human papillomavirus vaccination uptake: a cross-sectional study of girls from ethnic minority groups attending London schools

PubMed Central

Rockliffe, Lauren; Waller, Jo; Marlow, Laura A V; Forster, Alice S

2017-01-01

Objectives Research suggests that girls from ethnic minority groups are less likely to receive the human papillomavirus (HPV) vaccination than white British girls; however, the specific ethnic minority groups that have lower uptake have not been identified. This study aimed to examine the relationship between school-level uptake and ethnicity as well as uptake and other ethnicity-related factors, to understand which specific groups are less likely to receive the vaccination. Methods Aggregated uptake rates from 195 schools were obtained for each of the three recommended vaccine doses from 2008 to 2010. Census data at the lower super output area (LSOA) level for the postcode of each school were also obtained, describing the ethnic breakdown of the resident population (ethnicity, language spoken, religion, proficiency in English and duration of residency in the UK). These were used as proxy measures of the ethnic make-up of the schools. The most prevalent non-majority group for each ethnicity and ethnicity-related factor was assigned to each school. Analyses explored differences in uptake by ethnicity and ethnicity-related factors. Results No significant differences in vaccination uptake were found by ethnicity or ethnicity-related factors, although descriptive differences were apparent. Schools in areas where black ethnicities were the most prevalent non-white British ethnicities had consistently low rates of uptake for all doses. Schools in areas where some Asian ethnicities were the most prevalent non-white British ethnicities had consistently high rates of uptake for all doses. There was evidence of variability in mean uptake rates for ethnicities within ‘black’ and ‘Asian’ ethnic groups. Conclusions Future research would benefit from focusing on specific ethnicities rather than broad ethnic categories. Replication of this study with a larger sample and using complete individual-level data, collected on a national level, would provide a clearer indication of where ethnic differences in HPV vaccination uptake exist. PMID:28235971

Clinical and geographic patterns of rheumatic heart disease in outpatients attending cardiology clinic in western Kenya.

PubMed

Lumsden, Rebecca H; Akwanalo, Constantine; Chepkwony, Stella; Kithei, Anne; Omollo, Vincent; Holland, Thomas L; Bloomfield, Gerald S; O'Meara, Wendy P

2016-11-15

Rheumatic heart disease (RHD) remains a leading cause of cardiovascular mortality in sub-Saharan Africa. Identifying high risk populations and geographic patterns of disease is crucial to developing RHD prevention and screening strategies in endemic areas. To identify clinical and geographical trends in RHD throughout western Kenya METHODS: We conducted a retrospective chart review of all patients <50years old attending adult cardiology clinic at a national referral hospital in western Kenya. Demographic information, residential location and cardiac history were collected. We mapped the spatial distribution of cardiac disease rates and analyzed the effect of distance from the hospital on RHD status. Two-thirds (64%) of cardiology clinic patients <50years old (n=906) had RHD. RHD patients were younger (26 vs. 33years, p<0.001) and more often female (69% vs. 59%, p=0.001) than non-RHD patients. Global clustering of disease rates existed within 200km of the hospital with significant clustering of the RHD and non-RHD rate difference surrounding the hospital (Moran's I: 0.3, p=0.001). There was an interaction between ethnicity and distance from the hospital such that the odds of RHD decreased with further distance for Nilotes, but the odds of RHD increased with further distance for non-Nilotes CONCLUSION: Most adult cardiology patients treated at a national referral hospital in western Kenya have RHD. Young people and females are commonly affected. Ethnicity and distance to the hospital interdependently affect the odds of RHD. Future studies in this area should consider the impact of ethnic predisposition to RHD. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Genetic variants associated with fetal hemoglobin levels show the diverse ethnic origin in Colombian patients with sickle cell anemia.

PubMed

Fong, Cristian; Menzel, Stephan; Lizarralde, María Alejandra; Barreto, Guillermo

2015-01-01

Fetal hemoglobin is an important factor in modulating the severity of sickle cell anemia. Its level in peripheral blood underlies strong genetic determination. Associated loci with increased levels of fetal hemoglobin display population-specific allele frequencies. We investigated the presence and effect of known common genetic variants promoting fetal hemoglobin persistence (rs11886868, rs9399137, rs4895441, and rs7482144) in 60 Colombian patients with sickle cell anemia. Four single nucleotide polymorphisms (SNP) were genotyped by restriction fragment length polymorphisms (RFLP) and the use of the TaqMan procedure. Fetal hemoglobin (HbF) from these patients was quantified using the oxyhemoglobin alkaline denaturation technique. Genotype frequencies were compared with frequencies reported in global reference populations. We detected genetic variants in the four SNPs, reported to be associated with higher HbF levels for all four SNPs in the Colombian patients. Genetic association between SNPs and HbF levels did not reach statistical significance. The frequency of these variants reflected the specific ethnic make-up of our patient population: A high prevalence of rs7482144-'A' reflects the West-African origin of the sickle cell mutation, while high frequencies of rs4895441-'G' and rs11886868-'C' point to a significant influence of an Amerindian ethnic background in the Colombian sickle cell disease population. These results showed that in the sickle cell disease population in Colombia there is not a unique genetic background, but two (African and Amerindian). This unique genetic situation will provide opportunities for a further study of these loci, such as fine-mapping and molecular-biological investigation. Colombian patients are expected to yield a distinctive insight into the effect of modifier loci in sickle cell disease.

A cross-ethnic survey of CFB and SLC44A4, Indian ulcerative colitis GWAS hits, underscores their potential role in disease susceptibility

PubMed Central

Gupta, Aditi; Juyal, Garima; Sood, Ajit; Midha, Vandana; Yamazaki, Keiko; Vich Vila, Arnau; Esaki, Motohiro; Matsui, Toshiyuki; Takahashi, Atsushi; Kubo, Michiaki; Weersma, Rinse K; Thelma, B K

2017-01-01

The first ever genome-wide association study (GWAS) of ulcerative colitis in genetically distinct north Indian population identified two novel genes namely CFB and SLC44A4. Considering their biological relevance, we investigated allelic/genetic heterogeneity in these genes among ulcerative colitis cohorts of north Indian, Japanese and Dutch origin using high-density ImmunoChip case–control genotype data. Comparative linkage disequilibrium profiling and test of association were performed. Of the 28 CFB SNPs, similar strength of association was observed for rs4151657 (novel ulcerative colitis GWAS SNP) in north Indians (P=1.73 × 10−10) and Japanese (P=2.02 × 10−12) but not in the Dutch. Further, a three-marker haplotype was shared between north Indians and Japanese (P<10−8), but a different five-marker haplotype was associated (P=2.07 × 10−6) in the Dutch. Of the 22 SLC44A4 SNPs, rs2736428 (novel ulcerative colitis GWAS SNP) was found significantly associated in north Indians (P=4.94 × 10−10) and Japanese (P=3.37 × 10−9), but not among the Dutch. These results suggest (i) apparent allelic heterogeneity in CFB and genetic heterogeneity in SLC44A4 across different ethnic groups; (ii) shared ulcerative colitis genetic etiological factors among Asians; and finally (iii) re-exploration of GWAS findings together with high-density genotyping/sequencing and trans-ethnic fine mapping approaches may help identify shared and population-specific risk variants and enable to explain missing disease heritability. PMID:27759029

Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations.

PubMed

Dorajoo, R; Blakemore, A I F; Sim, X; Ong, R T-H; Ng, D P K; Seielstad, M; Wong, T-Y; Saw, S-M; Froguel, P; Liu, J; Tai, E-S

2012-01-01

Recent genome-wide association studies (GWAS) have identified 38 obesity-associated loci among European populations. However, their contribution to obesity in other ethnicities is largely unknown. We utilised five GWAS (N=10 482) from Chinese (three cohorts, including one with type 2 diabetes and another one of children), Malay and Indian ethnic groups from Singapore. Data sets were analysed individually and subsequently in combined meta-analysis for Z-score body-mass index (BMI) associations. Variants at the FTO locus showed the strongest associations with BMI Z-score after meta-analysis (P-values 1.16 × 10(-7)-7.95 × 10(-7)). We further detected associations with nine other index obesity variants close to the MC4R, GNPDA2, TMEM18, QPCTL/GIPR, BDNF, ETV5, MAP2K5/SKOR1, SEC16B and TNKS/MSRA loci (meta-analysis P-values ranging from 3.58 × 10(-4)-1.44 × 10(-2)). Three other single-nucleotide polymorphisms (SNPs) from CADM2, PTBP2 and FAIM2 were associated with BMI (P-value ≤ 0.0418) in at least one dataset. The neurotrophin/TRK pathway (P-value=0.029) was highlighted by pathway-based analysis of loci that had statistically significant associations among Singaporean populations. Our data confirm the role of FTO in obesity predisposition among Chinese, Malays and Indians, the three major Asian ethnic groups. We additionally detected associations for 12 obesity-associated SNPs among Singaporeans. Thus, it is likely that Europeans and Asians share some of the genetic predisposition to obesity. Furthermore, the neurotrophin/TRK signalling may have a central role for common obesity among Asians.

The factors associated to psychosocial stress among general practitioners in Lithuania. Cross-sectional study.

PubMed

Vanagas, Giedrius; Bihari-Axelsson, Susanna

2005-06-10

There are number of studies showing that general practice is one of the most stressful workplace among health care workers. Since Baltic States regained independence in 1990, the reform of the health care system took place in which new role and more responsibilities were allocated to general practitioners' in Lithuania. This study aimed to explore the psychosocial stress level among Lithuanian general practitioner's and examine the relationship between psychosocial stress and work characteristics. The cross-sectional study of 300 Lithuanian General practitioners. Psychosocial stress was investigated with a questionnaire based on the Reeder scale. Job demands were investigated with the R. Karasek scale. The analysis included descriptive statistics; interrelationship analysis between characteristics and multivariate logistic regression to estimate odds ratios for each of the independent variables in the model. Response rate 66% (N = 197). Our study highlighted highest prevalence of psychosocial stress among widowed, single and female general practitioners. Lowest prevalence of psychosocial stress was among males and older age general practitioners. Psychosocial stress occurs when job demands are high and job decision latitude is low (chi2 = 18,9; p < 0,01). The multivariate analysis shows that high job demands (OR 4,128; CI 2,102-8,104; p < 0,001), patient load more than 18 patients per day (OR 5,863; CI 1,549-22,188; p < 0,01) and young age of GP's (OR 6,874; CI 1,292-36,582; p < 0,05) can be assigned as significant predictors for psychosocial stress. One half of respondents suffering from work related psychosocial stress. High psychological workload demands combined with low decision latitude has the greatest impact to stress caseness among GP's. High job demands, high patient load and young age of GP's can be assigned as significant predictors of psychosocial stress among GP's.

Dental caries prevalence among 12-15-year-olds in Lithuania between 1983 and 2005.

PubMed

Milciuviene, Simona; Bendoraitiene, Egle; Andruskeviciene, Vilija; Narbutaite, Julija; Sakalauskiene, Jurgina; Vasiliauskiene, Ingrida; Slabsinskiene, Egle

2009-01-01

To analyze the dynamics of prevalence and severity of dental caries among 12- and 15-year-old schoolchildren in six regions of Lithuania. A total of 5910 schoolchildren aged 12 and 15 years were examined. Dental caries was diagnosed according to the criteria of World Health Organization. The prevalence of dental caries was calculated by dividing the number of children with caries by the number of all children examined and expressed as percentage. Severity of dental caries was described by DMF-T index. DMF-T indices of individual persons as well as each age group were determined. Oral hygiene was evaluated by a simplified oral hygiene index. Fluoride concentration in Kretinga was 1.6-2.2 ppm; in the other regions, it varied between 0.2 to 0.4 ppm. The prevalence of dental caries among 12-year-olds was 88.4% in 1983 and 85.5% in 2005; among 15-year-olds, it was 95.5% and 92.9%, respectively. Mean DMF-T score decreased from 4.5 (in 1983) to 3.7 (in 2005) among 12-year-olds and from 6.4 (in 1983) to 5.6 (in 2005) among 15-year-olds. Oral hygiene index decreased from 1.69 in 1983 to 1.34 in 2005 among 12-year-olds and from 1.46 to 1.22 among 15-year-olds, respectively. A tendency towards decrease in the prevalence and severity of dental caries was observed, when caries prevention program was running. Correlation between oral hygiene and DMF-T was observed in both age groups. Decreased prevalence and intensity of dental caries among 12- and 15-year-olds were associated with improved oral hygiene, usage of fluoride toothpaste, and fluoride content in drinking water.

[Changes of control of disorders of calcium and phosphorus metabolism in Lithuanian hemodialysis centers 1996-2003].

PubMed

Ziginskiene, Edita; Kuzminskis, Vytautas; Bumblyte, Inga Arūne; Kardauskaite, Zydrūne; Uogintaite, Jurgita

2005-01-01

The aim of the study was to evaluate the changes of the rate of disorders of calcium and phosphorus metabolism and their control in patients on hemodialysis (HD) in Lithuania in 1996-2003. Every December during this period we visited all HD centers of Lithuania and collected data on calcium-phosphorus metabolism in HD patients. 51.8% of HD patients in 1999 and 44.6% in 2003 had hyperphosphatemia (>1.8 mmol/l) (p<0.05). The mean phosphate concentration was 1.82+/-0.56 mmol/l in 2003 (p<0.05, comparing with 1.95+/-0.72 mmol/l in 1999 and 1.9+/-0.72 mmol/l in 2001). 7.1% of HD patients had hypocalcemia in 2003 and 7.8% hypercalcemia. Serum parathyroid hormone level was investigated only in 27.3% of HD patients in 1999 and 84.8% in 2003 (p<0.05). Use of alfacalcidol significantly decreased from 77.5% in 1998 to 29.4% in 2003, when the evaluation of serum parathyroid hormone increased (r=-0.911, p=0.03). Serum parathyroid hormone level was not analyzed for 59.8% of patients who used alfacalcidol and 59.4% of them had hyperphosphatemia in 1999 (6.3% and 32.9% in 2003, respectively; p<0.05). 10.7% of these patients had hypercalcemia in 2003. In summary, the correction of disorders of calcium and phosphorus metabolism in HD patients was insufficient but ameliorative. Monitoring of serum parathyroid hormone increased significantly during 1997-2003. The percentage of the precarious use of alfacalcidol decreased significantly when the evaluation of serum parathyroid hormone level became regular.

Education predicts cervical cancer survival: a Lithuanian cohort study.

PubMed

Vincerževskiene, Ieva; Jasilionis, Domantas; Austys, Donatas; Stukas, Rimantas; Kaceniene, Auguste; Smailyte, Giedre

2017-06-01

: We examined inequalities in cervical cancer survival in Lithuania by education and place of residence. : The study is based on the linked dataset that includes all records of the 2001 population Census, all records from Lithuanian Cancer Registry (cancer incidence) and all death and emigration records from Statistics Lithuania for the period between 6 April 2001 and 31 December 2009. The study group includes cervical cancers registered in the Cancer Registry from 1 January 2002 to 31 December 2006. Analysis was restricted to women who were 25-64 years old at the Census date (in total 1 866 cases). : During the study period there were 671 deaths corresponding to an overall 5-year survival proportion 64.13% (95% CI 61.86-66.31). Place of residence and education of cervical cancer patients had strong impact on survival; 5-year survival was higher in women living in urban areas than in rural (68.61 and 55.93%) and survival decreased with decreasing education: from 79.77% in highest education group to 64.85 and 50.48% in groups with secondary and lower than secondary education. The effect of place of residence declined when stage of disease was included in the model and became not significant in final model with education adjustment. The effect of education declined after inclusion of stage and other variables, however, remained significant. : We found that women with higher education experienced higher survival following a cervical cancer diagnosis, and stage of disease at the time of diagnosis explains only the part of observed differences. © The Author 2017. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

Workplace bullying and post-traumatic stress symptoms among family physicians in Lithuania: an occupation and region specific approach.

PubMed

Malinauskiene, Vilija; Einarsen, Staale

2014-12-01

The study investigated associations between workplace bullying and post-traumatic stress symptoms as compared to and controlled for associations between the latter and other psychosocial stress factors at work and in everyday life. The study employed a representative sample of Lithuanian family physicians, hence investigated a particularly resourceful occupational group in a geographical region earlier found to have a high risk context for exposure to bullying at work. With a response rate of 89.2%, a total of 323 family physicians filled in an anonymous questionnaire on workplace bullying, post-traumatic symptomatology (IES-R), other psychosocial stressors at work and in everyday life, personal health resources (sense of coherence), behavioral characteristics and demographic variables. The statistical software SPSS 14.0, Windows was used in the analysis. Associations were tested using a multivariate logistic regression analysis. A high prevalence of bullying was found among family physicians in Lithuania, with 13% of them experiencing severe workplace bullying and 17.3% experiencing more occasional incidents of bullying. The prevalence of post-traumatic stress symptoms was also high with 15.8% scoring above the standardized cut-off thresholds for post-traumatic stress disorder. The odds ratio (OR) of severe bullying for post-traumatic stress after adjustment for age and gender was 8.05 (95% confidence intervals (CI): 3.80-17.04). In the fully adjusted model it increased to 13.88 (95% CI: 4.68-41.13) indicating cumulative effects of all the investigated stressors. Workplace bullying is particularly prevalent among Lithuanian family physicians, as are the symptoms of post-traumatic distress. Strong associations between post-traumatic stress and exposure to severe bullying indicate that bullying is a significant source of mental health.

Peculiarities of medical sociology: application of social theories in analyzing health and medicine.

PubMed

Kaminskas, Raimundas; Darulis, Zilvinas

2007-01-01

To reveal the peculiarities of medical sociology introducing the application of social theories in analyzing public health and medicine. Comparative and descriptive analysis of scientific references found and current situation. During the last decade of the 20th century, the discussions about the sociology of health and medicine as separate discipline and its practical applications became more active. Main factors determined the growing importance of discipline were institutionalization of medicine and health care, changing patterns in doctor-patient relationships, different health perceptions, understanding of the influence of social factors on health, cardinal changes in the area of health technologies, consumeristic attitude towards health, appearance of market relationships within health care, and other global phenomena. In sociology, usual social theories such as structural functionalism, conflict, symbolic interaction, poststructuralism, feminist often attempt to explain the changes within health care. There is a relation of medical sociology and other types of sociology having common areas with medicine and health being analyzed in the article; social theories and their application in the field of health and medicine are being introduced attempting to explain the ongoing social changes in both Lithuania and the world. More and more attention in various areas of medical activities is being paid to the social aspects (both individual and society levels) of these activities, and there is a shift from applied sociology towards medical one. Despite the cessations of the development of medical sociology as separate branch of sciences, the researches of recent years are demonstrating obvious approaching modern research issues and methods, which do exist in contemporary world. Such tendencies show the prompt approaching of the academic community of Lithuania the general scientific standards which are dominating in the globalization-effected world.

Eliminating Rabies in Estonia

PubMed Central

Cliquet, Florence; Robardet, Emmanuelle; Must, Kylli; Laine, Marjana; Peik, Katrin; Picard-Meyer, Evelyne; Guiot, Anne-Laure; Niin, Enel

2012-01-01

The compulsory vaccination of pets, the recommended vaccination of farm animals in grazing areas and the extermination of stray animals did not succeed in eliminating rabies in Estonia because the virus was maintained in two main wildlife reservoirs, foxes and raccoon dogs. These two species became a priority target therefore in order to control rabies. Supported by the European Community, successive oral vaccination (OV) campaigns were conducted twice a year using Rabigen® SAG2 baits, beginning in autumn 2005 in North Estonia. They were then extended to the whole territory from spring 2006. Following the vaccination campaigns, the incidence of rabies cases dramatically decreased, with 266 cases in 2005, 114 in 2006, four in 2007 and three in 2008. Since March 2008, no rabies cases have been detected in Estonia other than three cases reported in summer 2009 and one case in January 2011, all in areas close to the South-Eastern border with Russia. The bait uptake was satisfactory, with tetracycline positivity rates ranging from 85% to 93% in foxes and from 82% to 88% in raccoon dogs. Immunisation rates evaluated by ELISA ranged from 34% to 55% in foxes and from 38% to 55% in raccoon dogs. The rabies situation in Estonia was compared to that of the other two Baltic States, Latvia and Lithuania. Despite regular OV campaigns conducted throughout their territory since 2006, and an improvement in the epidemiological situation, rabies has still not been eradicated in these countries. An analysis of the number of baits distributed and the funding allocated by the European Commission showed that the strategy for rabies control is more cost-effective in Estonia than in Latvia and Lithuania. PMID:22393461

Institutionalizing environmental protection through self-regulation: the case of environmental standards adoption in Lithuania.

NASA Astrophysics Data System (ADS)

Bileisis, Mantas; Misiune, Ieva

2017-04-01

The impacts of human activity in the environment have a global dimension, but there are no effective global governance instruments to enforce environmental standards. At the same time, many national governments lack incentives to pursue strict environmental policies. In this context, self-regulation is seen as an alternative venue to address environmental challenges. This work aims to identify factors that influence companies to engage in environmental self-regulation? For this aim in March 2015 a survey of 482 companies was conducted. The target group were companies operating in Lithuania that hold ISO14001 certificates - one of the most prolific instruments for self-regulation. The questionnaire was designed to test assumptions developed in new institutionalist literature which claim that common practices can emerge through isomorphism.- The results showed that the main motive for environmental self-regulation is the desire to improve company image, rather than protecting the environment per se. Another important finding was that the main source of pressure to adopt self-regulation was based less on the perceived demands but the customers. Rather the driver for the adoption was a feeling of a need no to fall behind industry leaders. Thus, normative isomorphism is the main mechanism through which environmental self-regulation proliferates. We claim for a rapid proliferation of environmental self-regulation perceived industry leaders need to be identified and they need to be persuaded that environmental standards are key for the development of the industry. However, this also raises questions of sustainability. Few industries have long standing leaders, and through successful investment and technological development new actors can arise and this may risk stalling or even reversing self-regulation.

Radionuclides from the Fukushima accident in the air over Lithuania: measurement and modelling approaches.

PubMed

Lujanienė, G; Byčenkienė, S; Povinec, P P; Gera, M

2012-12-01

Analyses of (131)I, (137)Cs and (134)Cs in airborne aerosols were carried out in daily samples in Vilnius, Lithuania after the Fukushima accident during the period of March-April, 2011. The activity concentrations of (131)I and (137)Cs ranged from 12 μBq/m(3) and 1.4 μBq/m(3) to 3700 μBq/m(3) and 1040 μBq/m(3), respectively. The activity concentration of (239,240)Pu in one aerosol sample collected from 23 March to 15 April, 2011 was found to be 44.5 nBq/m(3). The two maxima found in radionuclide concentrations were related to complicated long-range air mass transport from Japan across the Pacific, the North America and the Atlantic Ocean to Central Europe as indicated by modelling. HYSPLIT backward trajectories and meteorological data were applied for interpretation of activity variations of measured radionuclides observed at the site of investigation. (7)Be and (212)Pb activity concentrations and their ratios were used as tracers of vertical transport of air masses. Fukushima data were compared with the data obtained during the Chernobyl accident and in the post Chernobyl period. The activity concentrations of (131)I and (137)Cs were found to be by 4 orders of magnitude lower as compared to the Chernobyl accident. The activity ratio of (134)Cs/(137)Cs was around 1 with small variations only. The activity ratio of (238)Pu/(239,240)Pu in the aerosol sample was 1.2, indicating a presence of the spent fuel of different origin than that of the Chernobyl accident. Copyright © 2011 Elsevier Ltd. All rights reserved.

Accumulation and translocation peculiarities of (137)Cs and (40)K in the soil--plant system.

PubMed

Marčiulionienė, Danutė; Lukšienė, Benedikta; Jefanova, Olga

2015-12-01

Long-term investigations (1996-2008) were conducted into the (137)Cs and (40)K in the soil of forests, swamps and meadows in different regions of Lithuania, as well as in the plants growing in these media. The (137)Cs and (40)K activity concentrations, the (137)Cs/(40)K activity concentration ratio and accumulation, and translocation in the system, i.e. from the soil to plant roots to above-ground plant part of these radionuclides, were evaluated after gamma-spectrometric measurements using a high purity germanium (HPGe) detector. Based on the obtained data, it can be asserted that in the tested plant species, the (137)Cs and (40)K accumulation, the transfer from soil to roots and translocation within the plants depend on the plant species and environmental ecological conditions. The (137)Cs/(40)K activity concentration ratios in the same plant species in different regions of Lithuania are different and this ratio depends on the biotope (forest, swamp or meadow) in which the plant grows and on the location of the growing region. Based on the determined trends of statistically reliable inverse dependence between the activity concentrations in both soil and plants, it can be stated that the exchange of (137)Cs and (40)K in plants and soil is different. Different accumulations and translocations of investigated radionuclides in the same plant species indicate diverse biological metabolism of (137)Cs and its chemical analogue (40)K in plants. A competitive relationship exists between (137)Cs and (40)K in plants as well as in the soil. Copyright © 2015 Elsevier Ltd. All rights reserved.

Lifetime abuse and perceived social support among the elderly: a study from seven European countries.

PubMed

Eslami, Bahareh; Di Rosa, Mirko; Barros, Henrique; Stankunas, Mindaugas; Torres-Gonzalez, Francisco; Ioannidi-Kapolou, Elisabeth; Lindert, Jutta; Melchiorre, Maria Gabriella

2017-08-01

Being a victim of abuse during one's life course may affect social relations in later life. The aims of this study were to: (i) examine the association between lifetime abuse and perceived social support and (ii) identify correlates of perceived social support among older persons living in seven European countries. A sample of 4467 women and men aged 60-84 years living in Germany, Greece, Italy, Lithuania, Portugal, Spain and Sweden was collected through a cross-sectional population-based study. Abuse (psychological, physical, sexual, financial and injury) was assessed through interviews or interviews/self-response questionnaire based on the Conflict Tactics Scale-2 and the UK study on elder abuse. Perceived social support was assessed by the Multidimensional Scale of Perceived Social Support. Victims of lifetime abuse perceived poorer social support in later life. Multivariate analyses showed that high levels of perceived social support were associated with being from Greece and Lithuania (compared to Germany), being female, not living alone, consuming alcohol and physical activity. Poorer perceived social support was associated with being from Portugal, being old, having social benefits as the main source of income, experiencing financial strain and being exposed to lifetime psychological abuse and injuries. Our findings showed that exposure to psychological abuse and injuries across the lifespan were associated with low levels of perceived social support, emphasizing the importance of detection and appropriate treatment of victims of abuse during their life course. Future research should focus on coping strategies buffering the negative effects of abuse on social relationships. © The Author 2017. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

Biological therapy in inflammatory bowel diseases: Access in Central and Eastern Europe

PubMed Central

Rencz, Fanni; Péntek, Márta; Bortlik, Martin; Zagorowicz, Edyta; Hlavaty, Tibor; Śliwczyński, Andrzej; Diculescu, Mihai M; Kupcinskas, Limas; Gecse, Krisztina B; Gulácsi, László; Lakatos, Peter L

2015-01-01

Biological drugs opened up new horizons in the management of inflammatory bowel diseases (IBD). This study focuses on access to biological therapy in IBD patients across 9 selected Central and Eastern European (CEE) countries, namely Bulgaria, the Czech Republic, Estonia, Hungary, Latvia, Lithuania, Poland, Romania and Slovakia. Literature data on the epidemiology and disease burden of IBD in CEE countries was systematically reviewed. Moreover, we provide an estimation on prevalence of IBD as well as biological treatment rates. In all countries with the exception of Romania, lower biological treatment rates were observed in ulcerative colitis (UC) compared to Crohn’s disease despite the higher prevalence of UC. Great heterogeneity (up to 96-fold) was found in access to biologicals across the CEE countries. Poland, Bulgaria, Romania and the Baltic States are lagging behind Hungary, Slovakia and the Czech Republic in their access to biologicals. Variations of reimbursement policy may be one of the factors explaining the differences to a certain extent in Bulgaria, Latvia, Lithuania, and Poland, but association with other possible determinants (differences in prevalence and incidence, price of biologicals, total expenditure on health, geographical access, and cost-effectiveness results) was not proven. We assume, nevertheless, that health deterioration linked to IBD might be valued differently against other systemic inflammatory conditions in distinct countries and which may contribute to the immense diversity in the utilization of biological drugs for IBD. In conclusion, access to biologicals varies widely among CEE countries and this difference cannot be explained by epidemiological factors, drug prices or total health expenditure. Changes in reimbursement policy could contribute to better access to biologicals in some countries. PMID:25684937

Factors associated with patient satisfaction with primary care in Europe: results from the EUprimecare project.

PubMed

Sánchez-Piedra, Carlos Alberto; Prado-Galbarro, Francisco Javier; García-Pérez, Sonia; Santamera, Antonio Sarría

2014-01-01

EUprimecare is a study funded by the Seventh Framework Programme of the European Union, aimed at analysing the quality of the different models of primary care in Europe. The objective of this study was to describe and analyse the determinants associated with patient satisfaction in primary care in Europe. We conducted telephone population surveys among primary care users in each EUprimecare consortium country (Germany, Spain, Estonia, Finland, Hungary, Italy and Lithuania). The survey was conducted with 3020 patients and the questionnaire included sociodemographic variables, health status, and use and satisfaction with primary care services. We undertook descriptive analyses, bivariate correlations and an ordinal regression model to study the direct relationship between levels of satisfaction and the explanatory variables for demographics, health status and health services for patients. We present the regression coefficients (β) with 95% confidence intervals and associated tests of statistical significance. The mean age of the respondents was 51 years (SD 14.1). We found significant associations between the level of satisfaction and age (β = 0.008), specialist visits (β = -0.030), not having a general practitioner (β = 0.70), not measuring weight, cholesterol and blood pressure (β = 0.52), country (β1 Germany = -1.08 and β2 Lithuania = -0.60; β3 Hungary = 0.50 and β4 Italy = 0.53) and a better perception of health status (β = 0.33). Specialist visits had a negative association with satisfaction. Overall, the results indicate factors that may be related to greater satisfaction with primary care services: age, visits to a specialist, having a doctor assigned to primary care and measurement of control parameters are associated with a better perception of the care received.

Economic downturn results in tick-borne disease upsurge

PubMed Central

2011-01-01

Background The emergence of zoonoses is due both to changes in human activities and to changes in their natural wildlife cycles. One of the most significant vector-borne zoonoses in Europe, tick-borne encephalitis (TBE), doubled in incidence in 1993, largely as a consequence of the socio-economic transition from communism to capitalism and associated environmental changes. Methods To test the effect of the current economic recession, unemployment in 2009 and various socio-economic indices were compared to weather indices (derived from principal component analyses) as predictors for the change in TBE case numbers in 2009 relative to 2004-08, for 14 European countries. Results Greatest increases in TBE incidence occurred in Latvia, Lithuania and Poland (91, 79 and 45%, respectively). The weather was rejected as an explanatory variable. Indicators of high background levels of poverty, e.g. percent of household expenditure on food, were significant predictors. The increase in unemployment in 2009 relative to 2008 together with 'in-work risk of poverty' is the only case in which a multivariate model has a second significant term. Conclusion Background socio-economic conditions determine susceptibility to risk of TBE, while increased unemployment triggered a sudden increase in risk. Mechanisms behind this result may include reduced resistance to infection through stress; reduced uptake of costly vaccination; and more exposure of people to infected ticks in their forest habitat as they make greater use of wild forest foods, especially in those countries, Lithuania and Poland, with major marketing opportunities in such products. Recognition of these risk factors could allow more effective protection through education and a vaccination programme targeted at the economically most vulnerable. PMID:21406086

Impact of Financing Instruments and Strategies on the Wind Power Production Costs: A Case of Lithuania

NASA Astrophysics Data System (ADS)

Bobinaite, V.; Konstantinaviciute, I.

2018-04-01

The paper aims at demonstrating the relevance of financing instruments, their terms and financing strategies in relation to the cost of wind power production and the ability of wind power plant (PP) to participate in the electricity market in Lithuania. The extended approach to the Levelized Cost of Energy (LCOE) is applied. The feature of the extended approach lies in considering the lifetime cost and revenue received from the support measures. The research results have substantiated the relevance of financing instruments, their terms and strategies in relation to their impact on the LCOE and competitiveness of wind PP. It has been found that financing of wind PP through the traditional financing instruments (simple shares and bank loans) makes use of venture capital and bonds coming even in the absence of any support. It has been estimated that strategies consisting of different proportions of hard and soft loans, bonds, own and venture capital result in the average LCOE of 5.1-5.7 EURct/kWh (2000 kW), when the expected electricity selling price is 5.4 EURct/kWh. The financing strategies with higher shares of equity could impact by around 6 % higher LCOE compared to the strategies encompassing higher shares of debt. However, seeking to motivate venture capitalists, bond holders or other new financiers entering the wind power sector, support measures (feed-in tariff or investment subsidy) are relevant in case of 250 kW wind PP. It has been estimated that under the unsupported financing strategies, the average LCOE of 250 kW wind PP will be 7.8-8.8 EURct/kWh, but it will reduce by around 50 % if feed-in tariff or 50 % investment subsidy is applied.

Association of in utero exposure to maternal smoking with reduced semen quality and testis size in adulthood: a cross-sectional study of 1,770 young men from the general population in five European countries.

PubMed

Jensen, Tina Kold; Jørgensen, Niels; Punab, Margus; Haugen, Trine B; Suominen, Jyrki; Zilaitiene, Birute; Horte, Antero; Andersen, Anne-Grethe; Carlsen, Elisabeth; Magnus, Øystein; Matulevicius, Valentinas; Nermoen, Ingrid; Vierula, Matti; Keiding, Niels; Toppari, Jorma; Skakkebaek, Niels E

2004-01-01

Between 1996 and 1999, the authors invited all young men from five European countries who were undergoing compulsory medical examination for possible military service to participate in a study on male reproductive health. The participation rate was 19% in two cities in Denmark (n = 889), 17% in Oslo, Norway (n = 221), 13% in Turku, Finland (n = 313), 14% in Kaunas, Lithuania (n = 157), and 19% in Tartu, Estonia (n = 190). Each man provided a semen sample, was examined by a physician, and, in collaboration with his mother, completed a questionnaire about general and reproductive health, current smoking habits, and exposure to smoking in utero. After adjustment for confounding factors, men exposed to smoking in utero had a reduction in sperm concentration of 20.1% (95% confidence interval (CI): 6.8, 33.5) and a reduction in total sperm count of 24.5% (95% CI: 9.5, 39.5) in comparison with unexposed men. Percentages of motile and morphologically normal sperm cells were 1.85 (95% CI: 0.46, 3.23) and 0.64 (95% CI: -0.02, 1.30) percentage points lower, respectively, among men exposed in utero, and exposed men had a 1.15-ml (95% CI: 0.66, 1.64) smaller testis size. The associations were present when data from the study centers were analyzed separately (though not in Lithuania, where only 1% of mothers smoked during pregnancy), although the strength of the association varied. Maternal smoking may have long-term implications for the reproductive health of the offspring. This is another good reason to advise pregnant women to avoid smoking.

Short-term low-severity spring grassland fire impacts on soil extractable elements and soil ratios in Lithuania.

PubMed

Pereira, Paulo; Cerda, Artemi; Martin, Deborah; Úbeda, Xavier; Depellegrin, Daniel; Novara, Agata; Martínez-Murillo, Juan F; Brevik, Eric C; Menshov, Oleksandr; Comino, Jesus Rodrigo; Miesel, Jessica

2017-02-01

Spring grassland fires are common in boreal areas as a consequence of slash and burn agriculture used to remove dry grass to increase soil nutrient properties and crop production. However, few works have investigated fire impacts on these grassland ecosystems, especially in the immediate period after the fire. The objective of this work was to study the short-term impacts of a spring grassland fire in Lithuania. Four days after the fire we established a 400m 2 sampling grid within the burned area and in an adjacent unburned area with the same topographical, hydrological and pedological characteristics. We collected topsoil samples immediately after the fire (0months), 2, 5, 7 and 9months after the fire. We analysed soil pH, electrical conductivity (EC), major nutrients including calcium (Ca), magnesium (Mg), sodium (Na), and potassium (K), and the minor elements aluminium (Al), manganese (Mn), iron (Fe) and zinc (Zn). We also calculated the soil Na and K adsorption ratio (SPAR), Ca:Mg and Ca:Al. The results showed that this low-severity grassland fire significantly decreased soil pH, Al, and Mn but increased EC, Ca, Mg, and K,. There was no effect on Na, Fe, and Zn. There was a decrease of EC, Ca, Mg, and Na from 0months after the fire until 7months after the fire, with an increase during the last sampling period. Fire did not significantly affect SPAR. Ca:Mg decreased significantly immediately after the fire, but not to critical levels. Ca:Al increased after the fire, reducing the potential effects of Al on plants. Overall, fire impacts were mainly limited to the immediate period after the fire. Copyright © 2016 Elsevier B.V. All rights reserved.

Ethnic Identity in Context: Variations in Ethnic Exploration and Belonging within Parent, Same-Ethnic Peer, and Different-Ethnic Peer Relationships

ERIC Educational Resources Information Center

Kiang, Lisa; Fuligni, Andrew J.

2009-01-01

Within an ethnically diverse sample of young adults (n = 223, 26% Latin American, 14% Asian American, 32% Filipino American, 28% European American), average levels of ethnic identity was found to vary significantly across different relational contexts. Regardless of ethnicity, young adults reported highest levels of ethnic exploration and ethnic…

Ethnic variations in parental ethnic socialization and adolescent ethnic identity: a longitudinal study.

PubMed

Else-Quest, Nicole M; Morse, Emily

2015-01-01

Achievement of a positive ethnic identity has been linked to positive outcomes for ethnic minority youth and is fostered by parental ethnic socialization practices. In light of findings of variability in developmental trajectories and outcomes, we examined ethnic group variations in parents' ethnic socialization practices and adolescents' ethnic identity. Within a sample of 370 adolescents who self-identified as White, African American, Latino/a, or Asian American, and their parents, parental ethnic socialization practices (including preparation for bias, promotion of mistrust, and cultural socialization) and adolescent ethnic identity development (including identity exploration and commitment) were assessed at 10th and 11th grades. Consistent with predictions, African American youth reported higher levels of ethnic identity exploration and commitment than youth from other ethnic groups, and parents of African American youth tended to report higher levels of ethnic socialization than other parents. Parental cultural socialization significantly predicted adolescent ethnic identity exploration and commitment 1 year later; ethnicity did not moderate this link. Findings are discussed in the context of the schools and urban community from which the sample was recruited, highlighting the importance of sociocultural context in development. (PsycINFO Database Record (c) 2015 APA, all rights reserved).

Do dimensions of ethnic identity mediate the association between perceived ethnic group discrimination and depressive symptoms?

PubMed

Brittian, Aerika S; Kim, Su Yeong; Armenta, Brian E; Lee, Richard M; Umaña-Taylor, Adriana J; Schwartz, Seth J; Villalta, Ian K; Zamboanga, Byron L; Weisskirch, Robert S; Juang, Linda P; Castillo, Linda G; Hudson, Monika L

2015-01-01

Ethnic group discrimination represents a notable risk factor that may contribute to mental health problems among ethnic minority college students. However, cultural resources (e.g., ethnic identity) may promote psychological adjustment in the context of group-based discriminatory experiences. In the current study, we examined the associations between perceptions of ethnic group discrimination and depressive symptoms, and explored dimensions of ethnic identity (i.e., exploration, resolution, and affirmation) as mediators of this process among 2,315 ethnic minority college students (age 18 to 30 years; 37% Black, 63% Latino). Results indicated that perceived ethnic group discrimination was associated positively with depressive symptoms among students from both ethnic groups. The relationship between perceived ethnic group discrimination and depressive symptoms was mediated by ethnic identity affirmation for Latino students, but not for Black students. Ethnic identity resolution was negatively and indirectly associated with depressive symptoms through ethnic identity affirmation for both Black and Latino students. Implications for promoting ethnic minority college students' mental health and directions for future research are discussed. (PsycINFO Database Record (c) 2015 APA, all rights reserved).

Ethnic Identity and Perceived Stress Among Ethnically Diverse Immigrants.

PubMed

Espinosa, Adriana; Tikhonov, Aleksandr; Ellman, Lauren M; Kern, David M; Lui, Florence; Anglin, Deidre

2018-02-01

Recent empirical research suggests that having a strong ethnic identity may be associated with reduced perceived stress. However, the relationship between perceived stress and ethnic identity has not been tested in a large and ethnically diverse sample of immigrants. This study utilized a multi-group latent class analysis of ethnic identity on a sample of first and second generation immigrants (N = 1603), to determine ethnic identity classifications, and their relation to perceived stress. A 4-class ethnic identity structure best fit the data for this immigrant sample, and the proportion within each class varied by ethnicity, but not immigrant generation. High ethnic identity was found to be protective against perceived stress, and this finding was invariant across ethnicity. This study extends the findings of previous research on the protective effect of ethnic identity against perceived stress to immigrant populations of diverse ethnic origins.

Two siblings with early infantile myoclonic encephalopathy due to mutation in the gene encoding mitochondrial glutamate/H+ symporter SLC25A22.

PubMed

Cohen, Rony; Basel-Vanagaite, Lina; Goldberg-Stern, Hadassah; Halevy, Ayelet; Shuper, Avinoam; Feingold-Zadok, Michal; Behar, Doron M; Straussberg, Rachel

2014-11-01

To characterize a new subset of early myoclonic encephalopathy usually associated with metabolic etiologies with a new genetic entity. We describe two siblings with early myoclonic encephalopathy born to consanguineous parents of Arab Muslim origin from Israel. We used homozygosity mapping and candidate gene sequencing to reveal the genetic basis of the myoclonic syndrome. We found a rare missense mutation in the gene encoding one of the two mitochondrial glutamate/H symporters, SLC25A22. The phenotype of early myoclonic encephalopathy was first linked to the same mutation in 2005 in patients of the same ethnicity as our family. Owing to the devastating nature of this encephalopathy, we focus attention on its clinical history, epileptic semiology, distinct electroencephalography features, and genetic basis. We provide the evidence that an integrated diagnostic strategy combining homozygosity mapping with candidate gene sequencing is efficient in consanguineous families with highly heterogeneous autosomal recessive diseases. Copyright © 2014 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.