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Sample records for lithuanian locality relationships

  1. Lithuanian Astronomy

    NASA Astrophysics Data System (ADS)

    Sudzius, J.; Murdin, P.

    2002-01-01

    Lithuanian folklore, archaic calendars and terminology show that Lithuanians were interested in astronomy from ancient times. A lot of celestial bodies have names of Lithuanian origin that are not related to widely accepted ancient Greek mythology. For example, the Milky Way is named `Pauksciu Takas' (literally the way of birds), the constellation of the Great Bear `Didieji Grizulo Ratai' (literal...

  2. Lithuanians in America: Contributions to America, Relationship to Homeland, Integration into American Life, Retention of Ethnicity in America. Ethnic Heritage in America: Curriculum Materials in Elementary School Social Studies on Greeks, Jews, Lithuanians, and Ukrainians.

    ERIC Educational Resources Information Center

    Chicago Consortium for Inter-Ethnic Curriculum Development, IL.

    This ethnic heritage unit is about Lithuanians in the United States. The first section presents basic facts, such as a map of Lithuania, map of Eastern Europe, facts about Lithuania, principal dates in Lithuanian history, Lithuanian historical figures, bibliography about Lithuanians, and a list of Lithuanian organizations in the United States. The…

  3. The BICAMS Battery for Assessment of Lithuanian-Speaking Multiple Sclerosis Patients: Relationship with Age, Education, Disease Disability, and Duration.

    PubMed

    Giedraitienė, Nataša; Kizlaitienė, Rasa; Kaubrys, Gintaras

    2015-12-10

    BACKGROUND Assessment of cognitive impairment (CI) in multiple sclerosis (MS) patients is very useful, but it requires time-consuming expert evaluation with specialized materials. The Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) was created as a brief and specific instrument for the evaluation of CI. The aims of this study were to assess the cognitive status of MS patients by using the Lithuanian version of BICAMS, to evaluate the test-retest reliability of the Lithuanian version of BICAMS, and to measure the impact of CI on disability and duration of MS. MATERIAL AND METHODS We enrolled 50 MS patients and 20 cognitively normal control subjects, matched for age, gender, and level of education. Cognitive functions were assessed by the BICAMS tests, which include the Symbol Digit Modalities Test, the Brief Visuospatial Memory Test Revised, and the California Verbal Learning Test, 2nd edition. RESULTS MS patients performed significantly worse than controls on the 3 neuropsychological tests of BICAMS (p<0.001). Younger and intellectually employed persons performed significantly better on these tests than older persons, manual workers, or unemployed persons (p<0.05). MS patients with higher disability scores tended to perform worse on the tests (p<0.05), but we found no relationship between BICAMS test scores and the duration of the disease or relapse rate (p>0.05). Test-retest reliability was excellent for all 3 subtests (r>0.8, p<0.05). CONCLUSIONS Our study shows that BICAMS is a valid and acceptable cognitive assessment tool that can be recommended for routine use in Lithuania for assessing patients with MS.

  4. Methodology of Lithuanian climate atlas mapping

    NASA Astrophysics Data System (ADS)

    Valiukas, Donatas; Galvonaitė, Audronė; Česnulevičius, Algimantas

    2015-06-01

    Climate atlases summarize large sets of quantitative and qualitative data and are results of complex analytical cartographic work. These special geographical publications summarize long term meteorological observations, provide maps and figures which characterise different climate elements. Visual information is supplemented with explanatory texts. A lot of information on short and long term changes of climate elements were provided in published Lithuanian atlases (Atlas of Lithuanian SDR, 1981; Climate Atlas of Lithuania, 2013), as well as in prepared but unpublished Lithuanian Atlas (1989) and in upcoming new national atlas publications (National Atlas of Lithuania. 1st part, 2014). Climate atlases has to be constantly updated to be relevant and to describe current climate conditions. Comprehensive indicators of Lithuanian climate are provided in different cartographic publications. Different time periods, various data sets and diverse cartographic data analysis tools and visualisation methods were used in these different publications.

  5. Ethnolect Debate: Evidence from Jewish Lithuanian

    ERIC Educational Resources Information Center

    Verschik, Anna

    2010-01-01

    This article presents the concept of Jewish Lithuanian as a range of post-Yiddish varieties spoken by some Jews in Lithuania and seeks to synthesise findings in contemporary ethnolect studies and in the field of Jewish language research. The legitimacy of the term "ethnolect" is questioned by some researchers; however, it is argued that…

  6. [Medical Service of the Lithuanian Armed Forces].

    PubMed

    Golota, A S; Ivanov, V V; Krassii, A B; Mironov, V G; Soldatov, E A; Shalakhin A A

    2016-01-01

    The article is a brief description of the current state of Lithuanian Armed Forces medical service and is based on the study of the open access foreign sources. At the beginning, the general information about Lithuania, its Armed Forces, and their, medical service is presented. Then the medical service particular features are described, with more detail, namely, the organization of the inpatient and outpatient treatment, medical supply, scientific research, combat medicine, medical staff education and training, medical service personnel income.

  7. Spontaneous hybridization between Pinus mugo and Pinus sylvestris at the Lithuanian seaside: a morphological survey.

    PubMed

    Danusevičius, Darius; Marozas, Vitas; Brazaitis, Gediminas; Petrokas, Raimundas; Christensen, Knud Ib

    2012-01-01

    We address the problem of spontaneous hybridization between an exotic species Pinus mugo and the native/local P. sylvestris at the seaside spit of Kursiu Nerija in Lithuania. The objective was to identify spontaneous hybrids between P. mugo and P. sylvestris based on morphology traits among the individuals naturally regenerating at the seaside spit. The field inventory was carried out over the entire Lithuanian part of the spit, and 200 individuals morphologically intermediate between P. sylvestris and P. mugo were identified. Based on a weighted trait index, the intermediate individuals were grouped into two groups, one morphologically close to P. sylvestris and another close to P. mugo. The needle micromorphological traits of the putative hybrids were of intermediate values between P. mugo and P. sylvestris. The results provide a strong evidence of spontaneous hybridization between P. mugo and P. sylvestris in Lithuanian seaside spit of Kursiu Nerija.

  8. Spontaneous Hybridization between Pinus mugo and Pinus sylvestris at the Lithuanian Seaside: A Morphological Survey

    PubMed Central

    Danusevičius, Darius; Marozas, Vitas; Brazaitis, Gediminas; Petrokas, Raimundas; Christensen, Knud Ib

    2012-01-01

    We address the problem of spontaneous hybridization between an exotic species Pinus mugo and the native/local P. sylvestris at the seaside spit of Kursiu Nerija in Lithuania. The objective was to identify spontaneous hybrids between P. mugo and P. sylvestris based on morphology traits among the individuals naturally regenerating at the seaside spit. The field inventory was carried out over the entire Lithuanian part of the spit, and 200 individuals morphologically intermediate between P. sylvestris and P. mugo were identified. Based on a weighted trait index, the intermediate individuals were grouped into two groups, one morphologically close to P. sylvestris and another close to P. mugo. The needle micromorphological traits of the putative hybrids were of intermediate values between P. mugo and P. sylvestris. The results provide a strong evidence of spontaneous hybridization between P. mugo and P. sylvestris in Lithuanian seaside spit of Kursiu Nerija. PMID:22619615

  9. A catalogue of Lithuanian beetles (Insecta, Coleoptera)

    PubMed Central

    Tamutis, Vytautas; Tamutė, Brigita; Ferenca, Romas

    2011-01-01

    Abstract This paper presents the first complete and updated list of all 3597 species of beetles (Insecta: Coleoptera) belonging to 92 familiesfound and published in Lithuania until 2011, with comments also provided on the main systematic and nomenclatural changes since the last monographic treatment in two volumes (Pileckis and Monsevičius 1995, 1997). The introductory section provides a general overview of the main features of the territory of Lithuania, the origins and formation of the beetle fauna and their conservation, the faunistic investigations in Lithuania to date revealing the most important stages of the faunistic research process with reference to the most prominent scientists, an overview of their work, and their contribution to Lithuanian coleopteran faunal research. Species recorded in Lithuania by some authors without reliable evidence and requiring further confirmation with new data are presented in a separate list, consisting of 183 species. For the first time, analysis of errors in works of Lithuanian authors concerning data on coleopteran fauna has been conducted and these errors have been corrected. All available published and Internet sources on beetles found in Lithuania have been considered in the current study. Over 630 literature sources on species composition of beetles, their distribution in Lithuania and neighbouring countries, and taxonomic revisions and changes are reviewed and cited. An alphabetical list of these literature sources is presented. After revision of public beetle collections in Lithuania, the authors propose to remove 43 species from the beetle species list of the country on the grounds, that they have been wrongly identified or published by mistake. For reasons of clarity, 19 previously noted but later excluded species are included in the current checklist with comments. Based on faunal data from neighbouring countries, species expected to occur in Lithuania are matnioned. In total 1390 species are attributed to this

  10. Stable isotopes in Lithuanian bioarcheological material

    NASA Astrophysics Data System (ADS)

    Skipityte, Raminta; Jankauskas, Rimantas; Remeikis, Vidmantas

    2015-04-01

    Investigation of bioarcheological material of ancient human populations allows us to understand the subsistence behavior associated with various adaptations to the environment. Feeding habits are essential to the survival and growth of ancient populations. Stable isotope analysis is accepted tool in paleodiet (Schutkowski et al, 1999) and paleoenvironmental (Zernitskaya et al, 2014) studies. However, stable isotopes can be useful not only in investigating human feeding habits but also in describing social and cultural structure of the past populations (Le Huray and Schutkowski, 2005). Only few stable isotope investigations have been performed before in Lithuanian region suggesting a quite uniform diet between males and females and protein intake from freshwater fish and animal protein. Previously, stable isotope analysis has only been used to study a Stone Age population however, more recently studies have been conducted on Iron Age and Late medieval samples (Jacobs et al, 2009). Anyway, there was a need for more precise examination. Stable isotope analysis were performed on human bone collagen and apatite samples in this study. Data represented various ages (from 5-7th cent. to 18th cent.). Stable carbon and nitrogen isotope analysis on medieval populations indicated that individuals in studied sites in Lithuania were almost exclusively consuming C3 plants, C3 fed terrestrial animals, and some freshwater resources. Current investigation demonstrated social differences between elites and country people and is promising in paleodietary and daily life reconstruction. Acknowledgement I thank prof. dr. G. Grupe, Director of the Anthropological and Palaeoanatomical State Collection in Munich for providing the opportunity to work in her laboratory. The part of this work was funded by DAAD. Antanaitis-Jacobs, Indre, et al. "Diet in early Lithuanian prehistory and the new stable isotope evidence." Archaeologia Baltica 12 (2009): 12-30. Le Huray, Jonathan D., and Holger

  11. The effect of acidity on the distribution and symbiotic efficiency of rhizobia in Lithuanian soils

    NASA Astrophysics Data System (ADS)

    Lapinskas, E. B.

    2007-04-01

    The distribution and symbiotic efficiency of nodule bacteria Rhizobium leguminosarum_bv. trifolii F., Sinorhizobium meliloti D., Rhizobium galegae L., and Rhizobium leguminosarum bv. viciae F. in Lithuanian soils as dependent on the soil acidity were studied in the long-term field, pot, and laboratory experiments. The critical and optimal pH values controlling the distribution of rhizobia and the symbiotic nitrogen fixation were determined for every bacterial species. The relationship was found between the soil pH and the nitrogen-fixing capacity of rhizobia. A positive effect of liming of acid soils in combination with inoculation of legumes on the efficiency of symbiotic nitrogen fixation was demonstrated.

  12. Relationship between conductance fluctuation and weak localization in graphene

    NASA Astrophysics Data System (ADS)

    Terasawa, D.; Fukuda, A.; Fujimoto, A.; Ohno, Y.; Kanai, Y.; Matsumoto, K.

    2017-03-01

    The relationship between the universal conductance fluctuation and the weak localization effect in monolayer graphene is investigated. By comparing experimental results with the predictions of the weak localization theory for graphene, we find that the ratio of the elastic intervalley scattering time to the inelastic dephasing time varies in accordance with the conductance fluctuation; this is a clear evidence connecting the universal conductance fluctuation with the weak localization effect. We also find a series of scattering lengths that are related to the phase shifts caused by magnetic flux by Fourier analysis.

  13. Lithuanian women physicists: Current situation and involvement in gender projects

    NASA Astrophysics Data System (ADS)

    Šatkovskienė, Dalia; Ruželė, Živilė; Rutkūnienė, Živilė; Kupliauskienė, Alicija

    2015-12-01

    The changes in the situation of women in physics since the last Lithuanian country report are discussed on the basis of available statistics. The overall percentage of women physicists in research is 28%. Results show that there is a noticeable increase in female scientists in most phases of the academic career progression except in the highest positions. The results also show a permanent change in the awareness of gender-related issues in research. We also discuss the initiatives taken by Lithuanian women scientists to change the situation during three last years and their outcomes.

  14. The prevalence of malocclusion among 7-15-year-old Lithuanian schoolchildren.

    PubMed

    Sidlauskas, Antanas; Lopatiene, Kristina

    2009-01-01

    The epidemiological data on the prevalence of malocclusion is an important determinant in planning appropriate levels of orthodontic services. The occurrence of occlusal anomalies varies between different countries, ethnic and age groups. The aim of this study was to describe the prevalence of malocclusion among Lithuanian schoolchildren in the 7-9-, 10-12-, and 13-15-year age groups assessing occlusal morphology. The study included 1681 schoolchildren aged 7-15 years. The crowding, spacing, overbite, overjet, the relationship of the first upper and lower molars according Angle's classification, and posterior crossbite were assessed. The study demonstrated that only 257 children had normal occlusion, and 44 had undergone orthodontic treatment among them. The greatest overjet in the studied contingent was 11 mm, and the negative overjet - 3 mm. The overbite ranged between 0 and 6 mm with a mean of 2.29+/-1.23 mm. Posterior crossbite was recorded in 148 children (8.8%). This study showed that the prevalence of malocclusion among 7-15-year-old Lithuanian schoolchildren is 84.6%. The most common malocclusion was dental crowding. The upper dental arch crowding was registered for 44.1% and lower for 40.3% of all schoolchildren. The class I molar relationship was detected in 68.4% of the subjects, class II - in 27.7%, and class III - in 2.8%.

  15. Locally Epistatic Genomic Relationship Matrices for Genomic Association and Prediction

    PubMed Central

    Akdemir, Deniz; Jannink, Jean-Luc

    2015-01-01

    In plant and animal breeding studies a distinction is made between the genetic value (additive plus epistatic genetic effects) and the breeding value (additive genetic effects) of an individual since it is expected that some of the epistatic genetic effects will be lost due to recombination. In this article, we argue that the breeder can take advantage of the epistatic marker effects in regions of low recombination. The models introduced here aim to estimate local epistatic line heritability by using genetic map information and combining local additive and epistatic effects. To this end, we have used semiparametric mixed models with multiple local genomic relationship matrices with hierarchical designs. Elastic-net postprocessing was used to introduce sparsity. Our models produce good predictive performance along with useful explanatory information. PMID:25614606

  16. Improving the Evaluation Model for the Lithuanian Informatics Olympiads

    ERIC Educational Resources Information Center

    Skupiene, Jurate

    2010-01-01

    The Lithuanian Informatics Olympiads (LitIO) is a problem solving programming contest for students in secondary education. The work of the student to be evaluated is an algorithm designed by the student and implemented as a working program. The current evaluation process involves both automated (for correctness and performance of programs with the…

  17. Genetic Loci Associated with Allergic Sensitization in Lithuanians

    PubMed Central

    Šaulienė, Ingrida; Greičiuvienė, Jūratė; Šukienė, Laura; Juškevičiūtė, Neringa; Benner, Christian; Zinkevičienė, Auksė; Ripatti, Samuli; Donner, Kati; Kainov, Denis

    2015-01-01

    Allergic rhinitis (AR) is a common and complex disease. It is associated with environmental as well as genetic factors. Three recent genome-wide association studies (GWAS) reported altogether 47 single nucleotide polymorphisms (SNPs) associated with AR or allergic sensitization (AS) in Europeans and North Americans. Two follow up studies in Swedish and Chinese replicated 15 associations. In these studies individuals were selected based on the self-reported AR, or AR/AS diagnosed using blood IgE test or skin prick test (SPT), which were performed often without restriction to specific allergens. Here we performed third replication study in Lithuanians. We used SPT and carefully selected set of allergens prevalent in Lithuania, as well as Illumina Core Exome chip for SNP detection. We genotyped 270 SPT-positive individuals (137 Betulaceae -, 174 Poaceae-, 199 Artemisia-, 70 Helianthus-, 22 Alternaria-, 22 Cladosporium-, 140 mites-, 95 cat- and 97 dog dander-sensitive cases) and 162 SPT-negative controls. We found altogether 13 known SNPs associated with AS (p ≤0.05). Three SNPs were found in Lithuanians sensitive to several allergens, and 10 SNPs were found in Lithuanians sensitive to a certain allergen. For the first time, SNP rs7775228:C was associated with patient sensitivity to dog allergens (F_A=0,269, F_U=0.180, P=0.008). Thus, careful assessment of AS allowed us to detect known genetic variants associated with AS/AR in relatively small cohort of Lithuanians. PMID:26214689

  18. Sickly Americans, Kindly Portuguese, and Lithuanian Couch Potatoes.

    ERIC Educational Resources Information Center

    Bracey, Gerald W.

    2000-01-01

    Of 27 countries in a World Health Organization survey, American children report the most physical complaints, Portuguese children are most kind to one another, and Lithuanians watch more TV. U.S. and Czech teens are great dieters. Northern Irish, Scottish, and Finnish youngsters love computer games. (MLH)

  19. Local IRBs vs. federal agencies: shifting dynamics, systems, and relationships.

    PubMed

    Klitzman, Robert L

    2012-07-01

    How IRBs relate to federal agencies, and the implications of these relationships, have received little, if any, systematic study. I interviewed 46 IRB chairs, directors, administrators, and members, contacting the leadership of 60 U.S. IRBs (every fourth one in the list of the top 240 institutions by NIH funding), interviewing IRB leaders from 34 (response rate=55%). IRBs describe complex direct and indirect relationships with federal agencies that affect IRBs through audits, guidance documents, and other communications, and can generate problems and challenges. Researchers often blame IRBs for frustrations, but IRBs often serve as the "local face" of federal regulations and agencies and are "stuck in the middle." These data have critical implications for policy, practice, and research.

  20. Instantaneous relationship between solar inertial and local vertical local horizontal attitudes

    NASA Technical Reports Server (NTRS)

    Vickery, S. A.

    1977-01-01

    The instantaneous relationship between the Solar Inertial (SI) and Local Vertical Local Horizontal (LVLH) coordinate systems is derived. A method is presented for computation of the LVLH to SI rotational transformation matrix as a function of an input LVLH attitude and the corresponding look angles to the sun. Logic is provided for conversion between LVLH and SI attitudes expressed in terms of a pitch, yaw, roll Euler sequence. Documentation is included for a program which implements the logic on the Hewlett-Packard 97 programmable calculator.

  1. Lithuanian Freedom Fighters’ Tactics Resisting the Soviet Occupation 1944-1953

    DTIC Science & Technology

    2012-12-14

    Nazi efforts to recruit Lithuanian SS battalions, organizing an underground nationalistic press, etc., the overall goal of clandestine...assign SS -related tasks to the newly formed unit, General Povilas Plechavičius refused to comply. Therefore, soon after creation of the Lithuanian...Territorial Defense Force the Germans realized that the unit was pro-Lithuanian and posed a threat to the Nazi regime. As a result, the Germans arrested

  2. A Leesburg, Virginia, Service Club Introduces Lithuanian Communities to American Institutions.

    ERIC Educational Resources Information Center

    Raflo, Alan

    1993-01-01

    Describes how Kiwanis club members in Leesburg, Virginia, organized a successful trip to two Lithuanian communities without government support. U.S. visitors spoke to Lithuanians about the role of small businesses and civic clubs in the United States. Possible outcomes of the trip include continuing connections between businesses and between…

  3. Lithuanian female physicists: Reality and plans for the future

    NASA Astrophysics Data System (ADS)

    Šatkovskienė, Dalia; Giriunienė, Ramutė; Ruželė, Živilė; Rutkunienė, Živilė

    2013-03-01

    Changes in the issue of women in physics in Lithuanian in the three years since the 3rd IUPAP International Conference on Women in Physics are discussed on the basis of statistics as well as an exploratory study recently conducted among women physicists. The situation has changed slowly since 2008. However, the study shows that women physicists more clearly understand the inequities and the need for changes, including an active European Union mainstreaming policy targeted to ensure gender equality in the sciences, which gives hope for accelerating changes. Continued plans for improving women physicists' situation in Lithuania are discussed.

  4. 'They don't just come for Machu Picchu': locals' views of tourist-local sexual relationships in Cuzco, Peru.

    PubMed

    Bauer, Irmgard

    2008-08-01

    Sexual and romantic relationships between local people and tourists have long taken place. Such encounters are not a modern phenomenon, but the potential of sexually transmitted infections (STIs), including HIV/AIDS, warrants greater research into the issue. This paper analyses local people's views of local-tourist relationships in Cuzco/Peru. Data were obtained through in-depth interviews, participant and non-participant observation and informal discussions. Attraction based on physical difference was reportedly the main trigger for such relationships. Emerging themes discussed include issues of self-esteem, strategies of approach, tourists' motives, emotional involvement and expectations from such encounters. Levels of unprotected sexual behaviour and lack of STI awareness are of sufficient concern to recommend urgent action. Suggestions for sexual health education are made with particular emphasis on targeting local people involved in the tourism and hospitality industries.

  5. Soil sustainability study in Lithuanian alien forest stands

    NASA Astrophysics Data System (ADS)

    Čiuldiene, Dovile; Skridlaite, Grazina; Žalūdiene, Gaile; Askelsson, Cecilia; Armolaitis, Kestutis

    2016-04-01

    Tree species are shifting their natural ranges in response to climate changes (Saltré et al., 2013). Northern red oak has originated from North America, but was planted in Europe already in twentieth century. At present, it is considered as invasive species in Poland and at invasive stage in the Lithuanian forests (Riepsas and Straigyte, 2008). European larch naturally grows in Central Europe, but its range has been extended by planting it as far as the Nordic countries. According to a pollen study in peat soils, European larch naturally grew in Lithuania in the sixteenth century and was reintroduced 200 years ago (Jankauskas, 1954). Therefore, the global warming could accelerate the expansion of European larch and Northern red oak into Lithuanian forests. An urgent need appeared to evaluate an impact of those warmth-tolerant species on soil mineral chemistry and quality. New results on the determination of mineral weathering rates in alien forest stands using a PROFILE soil chemistry model were obtained during a doctoral study at the Institute of Forestry. Soil minerals were studied by a Scanning Electron Microscopy at the Institute of Geology and Geography. The results provided a lot of new information on soil weathering rates in Lithuania. The 47 and 157-year-old European larch (Larix decidua Mill.), 45 and 55-year-old Northern red oak (Quercus rubra L.) plantations and adjacent perennial grasslands were chosen for this study. The soils were classified as Luvisols and were developed from glaciofluvial deposits. The PROFILE model requires data of climate conditions (mean annual temperature and precipitation), chemical parameters of atmospheric deposition, forest plantation dendrometric and chemical (wood, foliage litter fall) characteristics, soil physical characteristics and mineral composition. A cation weathering rate (sum of Ca+Mg+ K) is 30% higher in a soil under the Northern red oak than in adjacent perennial grassland. Meanwhile, cation weathering rates

  6. [Legionellosis in meat-packing combines of the Lithuanian SSR].

    PubMed

    Bunikis, I A; Moteiunas, L I; Tartakovskiĭ, I S; Gotvianskaia, T P; Barkhatova, O I

    1989-01-01

    The article presents the results of a study of Legionella pneumophila morbidity in Lithuanian meat-processing factory workers, as well as the specific position of legionellosis in the fever diseases structure among the workers of the industry. The technique showed that Legionella pneumophila 1st serogroup seropositive reaction was traced among the healthy workers in 0.2% (antibody titer 1:64). Rather high percentage (7.1%) of persons with specific antibodies was found among those who had suffered the fever disease 6 month before the examination. Among 191 fever patients examined, in 35 (18.3%) cases antibodies against L. pneumophila were detected in diagnostic titers. In 26 workers legionellosis was diagnosed as a result of serologic testing, and Pontiac fever cases were predominant. 1 case was subsequently followed by pneumonia. A chronic nature of epidemic manifestations of legionellosis was established. The pathogenic antigen was detected in 4 of 32 water samples taken from the factory water pipes.

  7. The relationship between species detection probability and local extinction probability

    USGS Publications Warehouse

    Alpizar-Jara, R.; Nichols, J.D.; Hines, J.E.; Sauer, J.R.; Pollock, K.H.; Rosenberry, C.S.

    2004-01-01

    In community-level ecological studies, generally not all species present in sampled areas are detected. Many authors have proposed the use of estimation methods that allow detection probabilities that are < 1 and that are heterogeneous among species. These methods can also be used to estimate community-dynamic parameters such as species local extinction probability and turnover rates (Nichols et al. Ecol Appl 8:1213-1225; Conserv Biol 12:1390-1398). Here, we present an ad hoc approach to estimating community-level vital rates in the presence of joint heterogeneity of detection probabilities and vital rates. The method consists of partitioning the number of species into two groups using the detection frequencies and then estimating vital rates (e.g., local extinction probabilities) for each group. Estimators from each group are combined in a weighted estimator of vital rates that accounts for the effect of heterogeneity. Using data from the North American Breeding Bird Survey, we computed such estimates and tested the hypothesis that detection probabilities and local extinction probabilities were negatively related. Our analyses support the hypothesis that species detection probability covaries negatively with local probability of extinction and turnover rates. A simulation study was conducted to assess the performance of vital parameter estimators as well as other estimators relevant to questions about heterogeneity, such as coefficient of variation of detection probabilities and proportion of species in each group. Both the weighted estimator suggested in this paper and the original unweighted estimator for local extinction probability performed fairly well and provided no basis for preferring one to the other.

  8. The relationship between species detection probability and local extinction probability

    USGS Publications Warehouse

    Alpizar-Jara, R.; Nichols, J.D.; Hines, J.E.; Sauer, J.R.; Pollock, K.H.; Rosenberry, C.S.

    2004-01-01

    In community-level ecological studies, generally not all species present in sampled areas are detected. Many authors have proposed the use of estimation methods that allow detection probabilities that are <1 and that are heterogeneous among species. These methods can also be used to estimate community-dynamic parameters such as species local extinction probability and turnover rates (Nichols et al. Ecol Appl 8:1213-1225; Conserv Biol 12:1390-1398). Here, we present an ad hoc approach to estimating community-level vital rates in the presence of joint heterogeneity of detection probabilities and vital rates. The method consists of partitioning the number of species into two groups using the detection frequencies and then estimating vital rates (e.g., local extinction probabilities) for each group. Estimators from each group are combined in a weighted estimator of vital rates that accounts for the effect of heterogeneity. Using data from the North American Breeding Bird Survey, we computed such estimates and tested the hypothesis that detection probabilities and local extinction probabilities were negatively related. Our analyses support the hypothesis that species detection probability covaries negatively with local probability of extinction and turnover rates. A simulation study was conducted to assess the performance of vital parameter estimators as well as other estimators relevant to questions about heterogeneity, such as coefficient of variation of detection probabilities and proportion of species in each group. Both the weighted estimator suggested in this paper and the original unweighted estimator for local extinction probability performed fairly well and provided no basis for preferring one to the other.

  9. Landscape connectivity strengthens local-regional richness relationships in successional plant communities.

    PubMed

    Damschen, Ellen I; Brudvig, Lars A

    2012-04-01

    Local species diversity is maintained over ecological time by a balance between dispersal and species interactions. Local-regional species richness relationships are often used to investigate the relative importance of these two processes and the scales at which they operate. For communities undergoing succession, theory predicts a temporal progression in local-regional species richness relationships: from no relationship to positive linear to saturating. However, observational tests have been mixed, and experiments have been rare. Using a replicated large-scale experiment, we evaluate the impact of two dispersal-governing processes at the regional scale, connectivity and shape of the region (i.e., patches), on the progression of local-regional species richness relationships for plant communities undergoing succession. Regional connectivity accelerates the transition from no relationship to a positive linear relationship, while the shape of the region has no consistent effect nine years post-disturbance. Our results experimentally demonstrate the importance of dispersal in structuring local-regional species richness relationships over time and suggest that conservation corridors among regions can increase local diversity through regional enrichment of plant communities undergoing reassembly.

  10. Relationship Between Nutrient Enrichment and Benthic Function: Local Effects and Spatial Patterns

    EPA Science Inventory

    Eutrophication-induced changes to benthic structure and function are problems of enormous ecological and economic significance. Understanding the relationships between nutrient enrichment and effects, modifying factors such as localized transport time, and symptoms of eutrophica...

  11. Studies on Early Allergic Sensitization in the Lithuanian Birth Cohort

    PubMed Central

    Dubakiene, Ruta; Rudzeviciene, Odilija; Butiene, Indre; Sezaite, Indre; Petronyte, Malvina; Vaicekauskaite, Dalia; Zvirbliene, Aurelija

    2012-01-01

    Cohort studies are of great importance in defining the mechanism responsible for the development of allergy-associated diseases, such as atopic dermatitis, allergic asthma, and allergic rhinoconjunctivitis. Although these disorders share genetic and environmental risk factors, it is still under debate whether they are linked or develop sequentially along an atopic pathway. The current study was aimed to determine the pattern of allergy sensitization in the Lithuanian birth cohort “Alergemol” (n = 1558) established as a part of the multicenter European birth cohort “EuroPrevall”. Early sensitization to food allergens in the “Alergemol” birth cohort was analysed. The analysis revealed 1.3% and 2.8% of symptomatic-sensitized subjects at 6 and 12 months of age, respectively. The sensitization pattern in response to different allergens in the group of infants with food allergy symptoms was studied using allergological methods in vivo and in vitro. The impact of maternal and environmental risk factors on the early development of food allergy in at 6 and 12 months of age was evaluated. Our data showed that maternal diet, diseases, the use of antibiotics, and tobacco smoke during pregnancy had no significant impact on the early sensitization to food allergens. However, infants of atopic mothers were significantly more often sensitized to egg as compared to the infants of nonatopic mothers. PMID:22606067

  12. Technical note: Multiple wavelet coherence for untangling scale-specific and localized multivariate relationships in geosciences

    NASA Astrophysics Data System (ADS)

    Hu, Wei; Si, Bing Cheng

    2016-08-01

    The scale-specific and localized bivariate relationships in geosciences can be revealed using bivariate wavelet coherence. The objective of this study was to develop a multiple wavelet coherence method for examining scale-specific and localized multivariate relationships. Stationary and non-stationary artificial data sets, generated with the response variable as the summation of five predictor variables (cosine waves) with different scales, were used to test the new method. Comparisons were also conducted using existing multivariate methods, including multiple spectral coherence and multivariate empirical mode decomposition (MEMD). Results show that multiple spectral coherence is unable to identify localized multivariate relationships, and underestimates the scale-specific multivariate relationships for non-stationary processes. The MEMD method was able to separate all variables into components at the same set of scales, revealing scale-specific relationships when combined with multiple correlation coefficients, but has the same weakness as multiple spectral coherence. However, multiple wavelet coherences are able to identify scale-specific and localized multivariate relationships, as they are close to 1 at multiple scales and locations corresponding to those of predictor variables. Therefore, multiple wavelet coherence outperforms other common multivariate methods. Multiple wavelet coherence was applied to a real data set and revealed the optimal combination of factors for explaining temporal variation of free water evaporation at the Changwu site in China at multiple scale-location domains. Matlab codes for multiple wavelet coherence were developed and are provided in the Supplement.

  13. Mortality and cancer incidence among Lithuanian cement producing workers

    PubMed Central

    Smailyte, G; Kurtinaitis, J; Andersen, A

    2004-01-01

    Aims: To investigate mortality and cancer incidence of cement producing workers. Methods: A total of 2498 cement workers who have been employed at Portland cement producing departments for at least one year from 1956 to 2000 were followed up from 1 January 1978 to 31 December 2000. The cohort contributed 43 490 person-years to the study. Standardised incidence ratios (SIR) and standardised mortality ratios (SMR) were calculated as ratios between observed and expected numbers of cancers and deaths. The expected numbers were based on sex specific incidence and mortality rates for the total Lithuanian population. Results: Significantly increased SMRs were found for all malignant neoplasms (SMR 1.3, 95% CI 1.0 to 1.5) and for lung cancer (SMR 1.4, 95% CI 1.0 to 1.9) among male cement workers. SIR for all cancer sites was 1.2 (95% CI 1.0 to 1.4). Excess risk was found for cancer of the lung (SIR 1.5, 95% CI 1.1 to 2.1). The SIR for urinary bladder cancer was also increased (SIR 1.8, 95% CI 0.9 to 3.5). The overall cancer incidence was not increased among females (SIR 0.8, 95% CI 0.6 to 1.1). With increasing cumulated exposure to cement dust, there were indications of an increasing risk of lung and stomach cancers among males. Conclusions: This study supported the hypothesis that exposure to cement dust may increase the lung and bladder cancer risk. A dose related risk was found for stomach cancer, but no support was found for an increased risk of colorectal cancer. PMID:15150393

  14. Prediction of compounds in different local structure-activity relationship environments using emerging chemical patterns.

    PubMed

    Namasivayam, Vigneshwaran; Gupta-Ostermann, Disha; Balfer, Jenny; Heikamp, Kathrin; Bajorath, Jürgen

    2014-05-27

    Active compounds can participate in different local structure-activity relationship (SAR) environments and introduce different degrees of local SAR discontinuity, depending on their structural and potency relationships in data sets. Such SAR features have thus far mostly been analyzed using descriptive approaches, in particular, on the basis of activity landscape modeling. However, compounds in different local SAR environments have not yet been predicted. Herein, we adapt the emerging chemical patterns (ECP) method, a machine learning approach for compound classification, to systematically predict compounds with different local SAR characteristics. ECP analysis is shown to accurately assign many compounds to different local SAR environments across a variety of activity classes covering the entire range of observed local SARs. Control calculations using random forests and multiclass support vector machines were carried out and a variety of statistical performance measures were applied. In all instances, ECP calculations yielded comparable or better performance than controls. The approach presented herein can be applied to predict compounds that complement local SARs or prioritize compounds with different SAR characteristics.

  15. New Relationship with Schools: Evaluation of Trial Local Authorities and Schools. RR689

    ERIC Educational Resources Information Center

    Halsey, Karen; Judkins, Michelle; Atkinson, Mary; Rudd, Peter

    2005-01-01

    This summary outlines the key findings from a national evaluation of the first-year trials of the New Relationship with Schools (NRwS) carried out by a team at the National Foundation for Educational Research (NFER). The trials took place in the period September 2004 to July 2005 and involved 93 schools in eight local educational authorities…

  16. Enhancing Homeland Security Efforts by Building Strong Relationships between the Muslim Community and Local Law Enforcement

    DTIC Science & Technology

    2006-03-01

    between the groups and bridging the gap of cultural differences . This study sought to determine what factors associated with building...relationship is trust between the groups and bridging the gap of cultural differences . This study sought to determine what factors associated with... different roles local and federal law enforcement agencies play within the community for developing counterterrorism information.3 The process of building

  17. What Lithuanian Pupils Learn about Disability: Analysis of Attitudes and Content of Textbooks

    ERIC Educational Resources Information Center

    Ruskus, Jonas; Poceviciene, Rasa

    2006-01-01

    (Purpose) The purpose of this paper was to reveal how stereotyped representations of disability are manifested in school curriculum through the textbook content and the attitudes of participants of education. Research questions of this study were: How is disability represented in Lithuanian textbooks? What is the real discourse--that of…

  18. Harmonisation of the Educational Concept "Learning Outcome" in the Lithuanian Language

    ERIC Educational Resources Information Center

    Pukelis, Kestutis; Smetona, Antanas

    2011-01-01

    In this article, an example of translation of the English term "learning outcome" into the Lithuanian system of educational terms is used to discuss semantic peculiarities of translating professional terms. Consistency of a concept signifier and content of a concept, as well as their tune with already existing systems of educational…

  19. Changes in Lithuanian Pre-School and Pre-Primary Education Quality over the Last Decade

    ERIC Educational Resources Information Center

    Monkeviciene, Ona; Stankeviciene, Kristina

    2011-01-01

    Over the last decade, the changes in Lithuanian pre-school and pre-primary education have been predetermined by changes in paradigms of children's education and strategic education documents that provided for guidelines of high quality children's (self-)education, an increasing attention of society to the quality of children's education, training…

  20. On the relationship between regional and local species richness: a test of saturation theory.

    PubMed

    Starzomski, Brian M; Parker, Raenelle L; Srivastava, Diane S

    2008-07-01

    What are the local community consequences of changes in regional species richness and composition? To answer this question we followed the assembly of microarthropod communities in defaunated areas of moss, embedded in a larger moss "region." Regions were created by combining moss from spatially distinct sites, resulting in regional species pools that differed in both microarthropod richness and composition, but not area. Regional effects were less important than seasonality for local richness. Initial differences in regional richness had no direct effect on local species richness at any time along a successional gradient of 0.5-16 months. The structure of the regional pool affected both local richness and local composition, but these effects were seasonally dependent. Local species richness differed substantially between dates along the successional gradient and continued to increase 16 months after assembly began. To the best of our knowledge, this is the first critical test of saturation theory that experimentally manipulates regional richness. Further, our results failed to support the most important mechanisms proposed to explain the local richness-regional richness relationship. The results demonstrate that complicated interactions between assembly time, seasonality, and regional species pools contribute to structuring local species richness and composition in this community.

  1. Mobilizing Lithuanian Health Professionals as Community Peer Leaders for AIDS Prevention: An International Primary Health Care Collaboration.

    ERIC Educational Resources Information Center

    Norr, Kathleen F.; McElmurry, Beverly J.; Slutas, Frances M.; Christiansen, Carol D.; Misner, Susan J.; Marks, Beth A.

    2001-01-01

    Using primary health care and peer leadership models, U.S. nurses trained Lithuanian health professionals as community peer leaders in AIDS prevention. A national continuing education program is in place to sustain the initiative in Lithuania. (SK)

  2. Moment Magnitude ( M W) and Local Magnitude ( M L) Relationship for Earthquakes in Northeast India

    NASA Astrophysics Data System (ADS)

    Baruah, Santanu; Baruah, Saurabh; Bora, P. K.; Duarah, R.; Kalita, Aditya; Biswas, Rajib; Gogoi, N.; Kayal, J. R.

    2012-11-01

    An attempt has been made to examine an empirical relationship between moment magnitude ( M W) and local magnitude ( M L) for the earthquakes in the northeast Indian region. Some 364 earthquakes that were recorded during 1950-2009 are used in this study. Focal mechanism solutions of these earthquakes include 189 Harvard-CMT solutions ( M W ≥ 4.0) for the period 1976-2009, 61 published solutions and 114 solutions obtained for the local earthquakes (2.0 ≤ M L ≤ 5.0) recorded by a 27-station permanent broadband network during 2001-2009 in the region. The M W- M L relationships in seven selected zones of the region are determined by linear regression analysis. A significant variation in the M W- M L relationship and its zone specific dependence are reported here. It is found that M W is equivalent to M L with an average uncertainty of about 0.13 magnitude units. A single relationship is, however, not adequate to scale the entire northeast Indian region because of heterogeneous geologic and geotectonic environments where earthquakes occur due to collisions, subduction and complex intra-plate tectonics.

  3. 20 CFR 661.335 - What is a youth council, and what is its relationship to the Local Board?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... relationship to the Local Board? 661.335 Section 661.335 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR STATEWIDE AND LOCAL GOVERNANCE OF THE WORKFORCE INVESTMENT SYSTEM UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Local Governance Provisions § 661.335 What is a youth council,...

  4. Research Note Effect of drought and fires on the quality of water in Lithuanian rivers

    NASA Astrophysics Data System (ADS)

    Sakalauskiene, G.; Ignatavicius, G.

    In August and September 2002, concentrations of heavy metals (copper, lead, and zinc) were 21-74% more than in previous years in Lithuanian rivers. Such a sudden increase in heavy metal pollution reduces the value of any water body for fishing or recreation and poses a potential risk to the environment and to human health. Droughts in the summer of 2002 led to forest and peat bog fires all over Lithuania and may have caused the increase in concentrations of heavy metals detected in Lithuanian rivers in August 2002. The fires could have changed the pH in the top layers of the soil, overcome geochemical barriers in the soil and enabled heavy metals to migrate from the soil to the groundwater and from river bottom sediments to the surface water.

  5. Development of the hidden Markov models based Lithuanian speech recognition system

    NASA Astrophysics Data System (ADS)

    Ringeliene, Z.; Lipeika, A.

    2010-09-01

    The paper presents a prototype of the speaker-independent Lithuanian isolated word recognition system. The system is based on the hidden Markov models, a powerful statistical method for modeling speech signals. The prototype system can be used for Lithuanian words recognition investigations and is a good starting point for the development of a more sophisticated recognition system. The system graphical user interface is easy to control. Visualization of the entire recognition process is useful for analyzing of the recognition results. Based on this recognizer, a system for Web browser control by voice was developed. The program, which implements control by voice commands, was integrated in the speech recognition system. The system performance was evaluated by using different sets of acoustic models and vocabularies.

  6. Heterogeneity of nutritional habits of Lithuanian ethnolinguistic groups: population-based study

    PubMed Central

    Audronė, Jakaitienė; Donatas, Austys; Neringa, Burokienė; Vytautas, Kasiulevičius; Rimantas, Stukas; Vaidutis, Kučinskas

    2016-01-01

    Background. Lithuania is a Northern European country consisting of two main ethnolinguistic groups: Samogitians and Highlanders. The objective of the paper is to investigate differences in nutritional habits of 18–65-year-old Lithuanians living in different ethnolinguistic regions. Materials and methods. A representative, population-based, random sample of the 18–65-year-old ethnic Lithuanian population was interviewed from 17 December 2008 to 20 May 2013. Lithuanians living in their ethnolinguistic region for at least three generations were included (n = 1,133). We analysed responses to 12 questions about nutritional habits of respondents. For the univariate analysis, we applied the chi-squared test. For the clusterisation of the survey questions, we employed a multiple correspondence analysis (MCA). Results. Comparing Samogitians’ and Highlanders’ responses according to their gender, education, and place of residence, we observed more often significant differences (p < 0.05) for the urban population, respondents without higher education, and women. The nutrition of Highlanders was more consistent with national and WHO nutritional recommendations. Significant differences were obtained in the consumption of fish (p = 1.9 · 10–12), milk (p = 1.8 · 10–4) and grain products (p = 0.01). MCA revealed that all questions fall into three groups with a different composition for Samogitians and Highlanders. We failed to demonstrate the impact of different nutritional habits on the body mass index. Conclusions. According to the univariate and multivariate analysis, the nutritional habits of Lithuanian ethnolinguistic regions are heterogeneous. Dependency on an ethnolinguistic region might be considered an important factor for the preparation of appropriate health and nutrition education and disease prevention programmes. The issue of excess weight remains equally important for both ethnolinguistic groups. PMID:28356793

  7. Evaluation of leadership competencies of executives in Lithuanian public health institutions.

    PubMed

    Stankūnas, Mindaugas; Sauliūnė, Skirmantė; Smith, Tony; Avery, Mark; Šumskas, Linas; Czabanowska, Katarzyna

    2012-01-01

    BACKGROUND AND OBJECTIVE. Lithuanian and international public health experts emphasize the importance of leadership in public health. The aim of this study was to explore the self-assessed level of leadership competencies of executives in Lithuanian public health institutions. MATERIAL AND METHODS. Data were collected in a cross-sectional survey of executives of Lithuanian public health institutions in 2010. The total number of returned questionnaires was 55 (response rate, 58.5%). Respondents were asked about their competencies in leadership, teamwork, communication, and conflict management. The evaluation was carried out by analyzing the answers provided in the survey, which used a 5-point rating scale. In addition, the Belbin Team-Role Self-Perception Inventory and the Thomas-Kilmann Conflict Mode Instrument were used. RESULTS. The results showed that respondents were reserved or limited in their individual capacities through this evaluation of their leadership competencies. The mean score was 3.47 (SD, 0.71). Skills in competency areas of communication, teamwork, and conflict management were scored higher (3.73 [SD, 0.67], 3.73 [SD, 0.62], and 3.53 [SD, 0.63], respectively). Most of executives preferred to choose action-oriented roles (76.2%). The most common role was "implementer" (69.1%). "Avoiding" (52.7%) was the most common conflict solving strategy. The results showed that 89.1% of executives wanted to improve teamwork; 83.6%, leadership competencies; 81.8%, communication; and 80.0%, conflict management. CONCLUSIONS. The study results suggest that the executives of Lithuanian public health institutions evaluate their leadership competencies moderately. These results indicate the value of leadership training for public health executives.

  8. The level of endotoxins in hemodialysis water and dialysate in Lithuanian hemodialysis centers.

    PubMed

    Skarupskienė, Inga; Bumblytė, Inga Arūnė; Tamošaitis, Donatas; Venterienė, Jūratė; Kuzminskis, Vytautas

    2010-01-01

    The composition and quality of the dialysis fluid play an important role in the modulation of dialysis-related complications. During hemodialysis, patient's blood has a contact with dialysate through a semipermeable membrane. Bacterial endotoxins can pass through the membrane pores into the patient's blood and cause a silent chronic microinflammation. The aim of this study was to determine the level of endotoxins in hemodialysis water and dialysate in Lithuanian hemodialysis centers. Dialysis water (n=50) and dialysate (n=50) were collected from 91% (n=50) of all hemodialysis centers. The presence of bacterial endotoxins was evaluated using a sensitive Limulus amebocyte lysate test, which detects intact lipopolysaccharides. The level of endotoxins was lower than 0.25 EU/mL in 43 (86%) dialysis water samples and in 46 (92%) dialysate samples, and complied with the recommendations of the European Pharmacopoeia and the European Best Practice Guidelines for pure dialysis fluid. The dialysate of 39 (78%) Lithuanian hemodialysis centers complied with the definition of an ultrapure dialysis fluid. The water and dialysate were of insufficient quality in 14% and in 8% of Lithuanian hemodialysis centers, respectively, and this could be improved by the establishment of routine investigation of endotoxins.

  9. [Prof. Alfonsas Kaikaris -- the founder of the Lithuanian Pharmacy Museum: his personality and scientific activities].

    PubMed

    Gudiene, Vilma

    2002-01-01

    Alfonsas Kaikaris (1922-1997) was a professor of pharmacy at the Kaunas Medical Institute (now University), historian, museologist, founder of the Lithuanian Pharmacy Museum and of the field of pharmacy history in Lithuania. A. Kaikaris was born in Zagare in 1922. He received his pharmacy diploma in 1947 and began work at the university. Following the reorganization of the university into two institutes, he went to work in the Medical Institute, where he served as the vice dean of the Pharmacy and Stomatology Department from 1957 until 1963. He began to collect pharmaceutical artifacts in 1957. In 1973, the Institute provided a small room in the attic for these objects and so a small pharmacy museum, the first in Lithuania, was born. Thanks to the hard work of A. Kaikaris and others, today this museum has grown into the Pharmacy and Medical History Center of Lithuania, whose work is widely known throughout Europe. A. Kaikaris was also a member of the board of the Lithuanian Scientific Society and head of the Society's Pharmaceutical History Section from 1964 until he retired in 1987. He is the author of 67 scholarly papers and numerous popular articles and conference presentations. In 1988, he received the Paul Stradins Award from the Paul Stradins Medical History Museum in Riga, Latvia, and until his death in 1997 worked as a consultant to the Lithuanian Museum of the History of Medicine and Pharmacy.

  10. Application of Pont‘s Index to Lithuanian Individuals: a Pilot Study

    PubMed Central

    Smailiene, Dalia

    2015-01-01

    ABSTRACT Objectives A variety of diagnostic indices in orthodontics have been proposed to help in diagnosis and treatment planning. Pont’s Index was established to predict ideal maxillary dental arch width from the sum of mesiodistal widths of four upper incisors. The aim of this study was to assess the applicability of Pont’s Index to Lithuanian individuals. Material and Methods The sample comprised 52 subjects (age range from 18 to 35 years) with normal occlusion. Measurements were obtained directly from plaster casts using a digital calliper. Ideal arch widths were calculated for each subject according to Pont’s formulae, and the correlation coefficients were calculated between the measured and the calculated arch width values. Results Correlation between the measured width values and the corresponding values calculated according to Pont’s Index was moderate in all cases, with correlation coefficients values ranging from 0.59 (mandible) to 0.64 (maxilla) in first premolar’s area and 0.49 in both maxilla and mandible in first molar’s area (P < 0.05). Appropriate index values for Lithuanian individuals were assessed to be 85.57 in premolars and 66.24 in molars area. Conclusions According to the results of this study, there was no strong evidence to suggest that Pont’s Index could be reliably used to predict ideal arch width values in Lithuanian individuals. PMID:26904181

  11. General relationship of global topology, local dynamics, and directionality in large-scale brain networks.

    PubMed

    Moon, Joon-Young; Lee, UnCheol; Blain-Moraes, Stefanie; Mashour, George A

    2015-04-01

    The balance of global integration and functional specialization is a critical feature of efficient brain networks, but the relationship of global topology, local node dynamics and information flow across networks has yet to be identified. One critical step in elucidating this relationship is the identification of governing principles underlying the directionality of interactions between nodes. Here, we demonstrate such principles through analytical solutions based on the phase lead/lag relationships of general oscillator models in networks. We confirm analytical results with computational simulations using general model networks and anatomical brain networks, as well as high-density electroencephalography collected from humans in the conscious and anesthetized states. Analytical, computational, and empirical results demonstrate that network nodes with more connections (i.e., higher degrees) have larger amplitudes and are directional targets (phase lag) rather than sources (phase lead). The relationship of node degree and directionality therefore appears to be a fundamental property of networks, with direct applicability to brain function. These results provide a foundation for a principled understanding of information transfer across networks and also demonstrate that changes in directionality patterns across states of human consciousness are driven by alterations of brain network topology.

  12. Simplest relationship between local field potential and intracellular signals in layered neural tissue.

    PubMed

    Chizhov, Anton V; Sanchez-Aguilera, Alberto; Rodrigues, Serafim; de la Prida, Liset Menendez

    2015-12-01

    The relationship between the extracellularly measured electric field potential resulting from synaptic activity in an ensemble of neurons and intracellular signals in these neurons is an important but still open question. Based on a model neuron with a cylindrical dendrite and lumped soma, we derive a formula that substantiates a proportionality between the local field potential and the total somatic transmembrane current that emerges from the difference between the somatic and dendritic membrane potentials. The formula is tested by intra- and extracellular recordings of evoked synaptic responses in hippocampal slices. Additionally, the contribution of different membrane currents to the field potential is demonstrated in a two-population mean-field model. Our formalism, which allows for a simple estimation of unknown dendritic currents directly from somatic measurements, provides an interpretation of the local field potential in terms of intracellularly measurable synaptic signals. It is also applicable to the study of cortical activity using two-compartment neuronal population models.

  13. Simplest relationship between local field potential and intracellular signals in layered neural tissue

    NASA Astrophysics Data System (ADS)

    Chizhov, Anton V.; Sanchez-Aguilera, Alberto; Rodrigues, Serafim; de la Prida, Liset Menendez

    2015-12-01

    The relationship between the extracellularly measured electric field potential resulting from synaptic activity in an ensemble of neurons and intracellular signals in these neurons is an important but still open question. Based on a model neuron with a cylindrical dendrite and lumped soma, we derive a formula that substantiates a proportionality between the local field potential and the total somatic transmembrane current that emerges from the difference between the somatic and dendritic membrane potentials. The formula is tested by intra- and extracellular recordings of evoked synaptic responses in hippocampal slices. Additionally, the contribution of different membrane currents to the field potential is demonstrated in a two-population mean-field model. Our formalism, which allows for a simple estimation of unknown dendritic currents directly from somatic measurements, provides an interpretation of the local field potential in terms of intracellularly measurable synaptic signals. It is also applicable to the study of cortical activity using two-compartment neuronal population models.

  14. Biogeographic affinity helps explain productivity-richness relationships at regional and local scales

    USGS Publications Warehouse

    Harrison, S.; Grace, J.B.

    2007-01-01

    The unresolved question of what causes the observed positive relationship between large-scale productivity and species richness has long interested ecologists and evolutionists. Here we examine a potential explanation that we call the biogeographic affinity hypothesis, which proposes that the productivity-richness relationship is a function of species' climatic tolerances that in turn are shaped by the earth's climatic history combined with evolutionary niche conservatism. Using botanical data from regions and sites across California, we find support for a key prediction of this hypothesis, namely, that the productivity-species richness relationship differs strongly and predictably among groups of higher taxa on the basis of their biogeographic affinities (i.e., between families or genera primarily associated with north-temperate, semiarid, or desert zones). We also show that a consideration of biogeographic affinity can yield new insights on how productivity-richness patterns at large geographic scales filter down to affect patterns of species richness and composition within local communities. ?? 2007 by The University of Chicago. All rights reserved.

  15. The Relationship between Components of the Ohio Local School District Report Card and the Outcome of a School Tax Levy

    ERIC Educational Resources Information Center

    Wheatley, Vicki Ann

    2012-01-01

    The relationship between components of the local school district report card, school district typology, and the outcome of public school tax levy requests were examined in this study. A correlation research design was used to measure the relationship between the independent variables (performance index, average yearly progress, value added,…

  16. The relationship of active galactic nuclei & quasars with their local galaxy environment

    NASA Astrophysics Data System (ADS)

    Strand, Natalie Erin

    We explore how the local environment is related to properties of active galactic nuclei (AGNs) of various luminosities. Recent simulations and observations are converging on the view that the extreme luminosity of quasars, the brightest of AGNs, is fueled in major mergers of gas-rich galaxies. In such a picture, quasars, the highest luminosity AGNs, are expected to be located in regions with a higher density of galaxies on small scales where mergers are more likely to take place. However, in this picture, the activity observed in low-luminosity AGNs is due to secular processes that are less dependent on the local galaxy density. To test this hypothesis, we compare the local photometric galaxy density on kiloparsec scales around spectroscopic type I and type II quasars to the local density around lower-luminosity spectroscopic type I and type II AGNs. To minimize projection effects and evolution in the photometric galaxy sample we use to characterize AGN environments, we place our random control sample at the same redshift as our AGNs and impose a narrow redshift window around both the AGNs and control targets. Our results support these merger models for bright AGN origins. We find that the brightest sources have overdensities that increase on the smallest scales compared to dimmer sources. In addition, we investigate the nature of the quasar and AGN environments themselves and find that the increased overdensity of early-type galaxies in the environments of bright type I sources suggests that they are located in richer cluster environments than dim sources. We measure increased environment overdensity with increased quasar black hole mass, consistent with the well- known M DMH - M BH relationship, and find evidence for quenching in the environments of high accretion efficiency type I quasars.

  17. Subgingival microbial communities in Leukocyte Adhesion Deficiency and their relationship with local immunopathology.

    PubMed

    Moutsopoulos, Niki M; Chalmers, Natalia I; Barb, Jennifer J; Abusleme, Loreto; Greenwell-Wild, Teresa; Dutzan, Nicolas; Paster, Bruce J; Munson, Peter J; Fine, Daniel H; Uzel, Gulbu; Holland, Steven M

    2015-03-01

    Leukocyte Adhesion Deficiency I (LAD-I) is a primary immunodeficiency caused by single gene mutations in the CD18 subunit of β2 integrins which result in defective transmigration of neutrophils into the tissues. Affected patients suffer from recurrent life threatening infections and severe oral disease (periodontitis). Microbial communities in the local environment (subgingival plaque) are thought to be the triggers for inflammatory periodontitis, yet little is known regarding the microbial communities associated with LAD-I periodontitis. Here we present the first comprehensive characterization of the subgingival communities in LAD-I, using a 16S rRNA gene-based microarray, and investigate the relationship of this tooth adherent microbiome to the local immunopathology of periodontitis. We show that the LAD subgingival microbiome is distinct from that of health and Localized Aggressive Periodontitits. Select periodontitis-associated species in the LAD microbiome included Parvimonas micra, Porphyromonas endodontalis, Eubacterium brachy and Treponema species. Pseudomonas aeruginosa, a bacterium not typically found in subgingival plaque is detected in LAD-I. We suggest that microbial products from LAD-associated communities may have a role in stimulating the local inflammatory response. We demonstrate that bacterial LPS translocates into the lesions of LAD-periodontitis potentially triggering immunopathology. We also show in in vitro assays with human macrophages and in vivo in animal models that microbial products from LAD-associated subgingival plaque trigger IL-23-related immune responses, which have been shown to dominate in patient lesions. In conclusion, our current study characterizes the subgingival microbial communities in LAD-periodontitis and supports their role as triggers of disease pathogenesis.

  18. Subgingival Microbial Communities in Leukocyte Adhesion Deficiency and Their Relationship with Local Immunopathology

    PubMed Central

    Moutsopoulos, Niki M.; Abusleme, Loreto; Greenwell-Wild, Teresa; Dutzan, Nicolas; Paster, Bruce J.; Munson, Peter J.; Fine, Daniel H.; Uzel, Gulbu; Holland, Steven M.

    2015-01-01

    Leukocyte Adhesion Deficiency I (LAD-I) is a primary immunodeficiency caused by single gene mutations in the CD18 subunit of β2 integrins which result in defective transmigration of neutrophils into the tissues. Affected patients suffer from recurrent life threatening infections and severe oral disease (periodontitis). Microbial communities in the local environment (subgingival plaque) are thought to be the triggers for inflammatory periodontitis, yet little is known regarding the microbial communities associated with LAD-I periodontitis. Here we present the first comprehensive characterization of the subgingival communities in LAD-I, using a 16S rRNA gene-based microarray, and investigate the relationship of this tooth adherent microbiome to the local immunopathology of periodontitis. We show that the LAD subgingival microbiome is distinct from that of health and Localized Aggressive Periodontitits. Select periodontitis-associated species in the LAD microbiome included Parvimonas micra, Porphyromonas endodontalis, Eubacterium brachy and Treponema species. Pseudomonas aeruginosa, a bacterium not typically found in subgingival plaque is detected in LAD-I. We suggest that microbial products from LAD-associated communities may have a role in stimulating the local inflammatory response. We demonstrate that bacterial LPS translocates into the lesions of LAD-periodontitis potentially triggering immunopathology. We also show in in vitro assays with human macrophages and in vivo in animal models that microbial products from LAD-associated subgingival plaque trigger IL-23-related immune responses, which have been shown to dominate in patient lesions. In conclusion, our current study characterizes the subgingival microbial communities in LAD-periodontitis and supports their role as triggers of disease pathogenesis. PMID:25741691

  19. Classification of protein motifs based on subcellular localization uncovers evolutionary relationships at both sequence and functional levels

    PubMed Central

    2013-01-01

    Background Most proteins have evolved in specific cellular compartments that limit their functions and potential interactions. On the other hand, motifs define amino acid arrangements conserved between protein family members and represent powerful tools for assigning function to protein sequences. The ideal motif would identify all members of a protein family but in practice many motifs identify both family members and unrelated proteins, referred to as True Positive (TP) and False Positive (FP) sequences, respectively. Results To address the relationship between protein motifs, protein function and cellular localization, we systematically assigned subcellular localization data to motif sequences from the comprehensive PROSITE sequence motif database. Using this data we analyzed relationships between localization and function. We find that TPs and FPs have a strong tendency to localize in different compartments. When multiple localizations are considered, TPs are usually distributed between related cellular compartments. We also identified cases where FPs are concentrated in particular subcellular regions, indicating possible functional or evolutionary relationships with TP sequences of the same motif. Conclusions Our findings suggest that the systematic examination of subcellular localization has the potential to uncover evolutionary and functional relationships between motif-containing sequences. We believe that this type of analysis complements existing motif annotations and could aid in their interpretation. Our results shed light on the evolution of cellular organelles and potentially establish the basis for new subcellular localization and function prediction algorithms. PMID:23865897

  20. HGDP and HapMap analysis by Ancestry Mapper reveals local and global population relationships.

    PubMed

    Magalhães, Tiago R; Casey, Jillian P; Conroy, Judith; Regan, Regina; Fitzpatrick, Darren J; Shah, Naisha; Sobral, João; Ennis, Sean

    2012-01-01

    Knowledge of human origins, migrations, and expansions is greatly enhanced by the availability of large datasets of genetic information from different populations and by the development of bioinformatic tools used to analyze the data. We present Ancestry Mapper, which we believe improves on existing methods, for the assignment of genetic ancestry to an individual and to study the relationships between local and global populations. The principle function of the method, named Ancestry Mapper, is to give each individual analyzed a genetic identifier, made up of just 51 genetic coordinates, that corresponds to its relationship to the HGDP reference population. As a consequence, the Ancestry Mapper Id (AMid) has intrinsic biological meaning and provides a tool to measure similarity between world populations. We applied Ancestry Mapper to a dataset comprised of the HGDP and HapMap data. The results show distinctions at the continental level, while simultaneously giving details at the population level. We clustered AMids of HGDP/HapMap and observe a recapitulation of human migrations: for a small number of clusters, individuals are grouped according to continental origins; for a larger number of clusters, regional and population distinctions are evident. Calculating distances between AMids allows us to infer ancestry. The number of coordinates is expandable, increasing the power of Ancestry Mapper. An R package called Ancestry Mapper is available to apply this method to any high density genomic data set.

  1. HGDP and HapMap Analysis by Ancestry Mapper Reveals Local and Global Population Relationships

    PubMed Central

    Magalhães, Tiago R.; Casey, Jillian P.; Conroy, Judith; Regan, Regina; Fitzpatrick, Darren J.; Shah, Naisha; Sobral, João; Ennis, Sean

    2012-01-01

    Knowledge of human origins, migrations, and expansions is greatly enhanced by the availability of large datasets of genetic information from different populations and by the development of bioinformatic tools used to analyze the data. We present Ancestry Mapper, which we believe improves on existing methods, for the assignment of genetic ancestry to an individual and to study the relationships between local and global populations. The principle function of the method, named Ancestry Mapper, is to give each individual analyzed a genetic identifier, made up of just 51 genetic coordinates, that corresponds to its relationship to the HGDP reference population. As a consequence, the Ancestry Mapper Id (AMid) has intrinsic biological meaning and provides a tool to measure similarity between world populations. We applied Ancestry Mapper to a dataset comprised of the HGDP and HapMap data. The results show distinctions at the continental level, while simultaneously giving details at the population level. We clustered AMids of HGDP/HapMap and observe a recapitulation of human migrations: for a small number of clusters, individuals are grouped according to continental origins; for a larger number of clusters, regional and population distinctions are evident. Calculating distances between AMids allows us to infer ancestry. The number of coordinates is expandable, increasing the power of Ancestry Mapper. An R package called Ancestry Mapper is available to apply this method to any high density genomic data set. PMID:23189146

  2. Managerial attitude to the implementation of quality management systems in Lithuanian support treatment and nursing hospitals

    PubMed Central

    Buciuniene, Ilona; Malciankina, Sonata; Lydeka, Zigmas; Kazlauskaite, Ruta

    2006-01-01

    Background The regulations of the Quality Management System (QMS) implementation in health care organizations were approved by the Lithuanian Ministry of Health in 1998. Following the above regulations, general managers of health care organizations had to initiate the QMS implementation in hospitals. As no research on the QMS implementation has been carried out in Lithuanian support treatment and nursing hospitals since, the objective of this study is to assess its current stage from a managerial perspective. Methods A questionnaire survey of general managers of Lithuanian support treatment and nursing hospitals was carried out in the period of January through March 2005. Majority of the items included in the questionnaire were measured on a seven-point Likert scale. During the survey, a total of 72 questionnaires was distributed, out of which 58 filled-in ones were returned (response rate 80.6 per cent; standard sampling error 0.029 at 95 per cent level of confidence). Results Quality Management Systems were found operating in 39.7 per cent of support treatment and nursing hospitals and currently under implementation in 46.6 per cent of hospitals (13.7% still do not have it). The mean of the respondents' perceived QMS significance is 5.8 (on a seven-point scale). The most critical issues related to the QMS implementation include procedure development (5.5), lack of financial resources (5.4) and information (5.1), and development of work guidelines (4.6), while improved responsibility and power sharing (5.2), better service quality (5.1) and higher patient satisfaction (5.1) were perceived by the respondents as the key QMS benefits. The level of satisfaction with the QMS among the management of the surveyed hospitals is mediocre (3.6). However it was found to be higher among respondents who were more competent in quality management, were familiar with ISO 9000 standards, and had higher numbers of employees trained in quality management. Conclusion QMSs are

  3. Macular SD-OCT Outcome Measures: Comparison of Local Structure-Function Relationships and Dynamic Range

    PubMed Central

    Miraftabi, Arezoo; Amini, Navid; Morales, Esteban; Henry, Sharon; Yu, Fei; Afifi, Abdolmonem; Coleman, Anne L.; Caprioli, Joseph; Nouri-Mahdavi, Kouros

    2016-01-01

    Purpose We tested the hypothesis that the macular ganglion cell layer (GCL) thickness demonstrates a stronger structure-function (SF) relationship and extends the useful range of macular measurements compared with combined macular inner layer or full thickness. Methods Ninety-eight glaucomatous eyes and eight normal eyes with macular spectral domain optical coherence tomography (SD-OCT) volume scans and 10-2 visual fields were enrolled. Inner plexiform layer (IPL), GCL, macular retinal nerve fiber layer (mRNFL), ganglion cell-inner plexiform layer (GCIPL), ganglion cell complex (GCC), and full thickness (FT) measurements were calculated for 8 × 8 arrays of 3° superpixels. Main outcome measures were local structure-function relationships between macular superpixels and corresponding sensitivities on 10-2 fields after adjusting for ganglion cell displacement, dynamic range of measurements, and the change point (total deviation value where macular parameters reached measurement floor). Results Median (interquartile range [IQR]) mean deviation was −7.2 (−11.6 to −3.2) dB in glaucoma eyes. Strength of SF relationships was highest for GCIPL, GCL, GCC, and IPL (ρ = 0.635, 0.627, 0.621, and 0.577, respectively; P ≤ 0.046 for comparisons against GCIPL). Highest SF correlations coincided with the peak of GCL thickness, where the dynamic range was widest for FT (81.1 μm), followed by GCC (65.7 μm), GCIPL (54.9 μm), GCL (35.2 μm), mRNFL (27.5 μm), and IPL (20.9 μm). Change points were similar for all macular parameters (−7.8 to −8.9 dB). Conclusions GCIPL, GCL, and GCC demonstrated comparable SF relationships while FT, GCC, and GCIPL had the widest dynamic range. Measurement of GCL did not extend the range of useful structural measurements. Measuring GCL does not provide any advantage for detection of progression with current SD-OCT technology. PMID:27623336

  4. [Psychological and psychiatric problems in cancer patients: relationship to the localization of the disease].

    PubMed

    Moussas, G I; Papadopoulou, A G; Christodoulaki, A G; Karkanias, A P

    2012-01-01

    , affect body image and cause feelings of embarrassment with severe consequences on the patient's sense of wellbeing, his or her daily activities, interpersonal relationships or sexuality. Depressive symptoms often occur in prodromal stages of pancreatic cancer. Depression is a common diagnosis in patients with prostate cancer. Prostatectomy negatively affects patient's self-esteem, because it might be experienced as a threat to his sexual life. Disfigurement is related to skin cancer because of both cancer and surgical procedures. Therefore, it is a challenge for modern psycho-oncology to identify those patients who are vulnerable in developing psychiatric symptoms, to early diagnose anxiety and depression and to use psychotherapeutic interventions targeting individual psychological and psychiatric problems in relation to the localization of disease in the human body.

  5. The Accuracy of the Osteological Sexing of Cremated Human Remains: A Test Based on Grave Goods from East Lithuanian Barrows.

    PubMed

    Kurila, Laurynas

    2015-12-01

    The accuracy of the sex determination of cremated human remains is one of the vital parameters for archaeologists and skeletal anthropologists dealing with cremations. Few studies have so far aimed at testing it. In the present paper, the accuracy of the sexing techniques was assessed by paralleling biological sex (identified morphologically) to gender (presumed on the basis of the grave goods which accompanied the deceased). A collection of cremated bones from East Lithuanian barrows (c. fourth/fifth--eleventh/twelfth centuries AD) was employed. The fragmentary nature and poor state of the bones generally represents cremains from similar archaeological contexts. The database inevitably underwent several stages of filtration. Out of 364 cremations with a minimum of 445 individuals, only 157 were sexed single adult burials, of which only 81 had "gender-related" grave goods. The relationship of artefact type to gender was defined statistically, revising the results in line with the chronological and typological differences and the probable symbolism of the grave goods. Sex and gender coincided in 56 cases (69.14%), but a considerable distance between the results for both sexes was observed. Biological females displayed a fairly high match level, i.e. 35 out of the 41 (85.37%) individuals osteologically identified as females had been given "feminine" items. The burials of biological males, on the other hand, yielded a surprisingly low match rate, i.e. only 21 out of 40 (52.50%). This disparity suggests a possible misinterpretation of grave goods as gender markers, rather than (only?) erroneous sexing. It is thus argued that for females, the mean value for the accuracy of sexing is 85.5%. In most cases, such precision is entirely satisfactory for the analysis of a poorly-preserved osteological material. For males, however, the accuracy is likely to fall somewhere in the range between 52.5 and 85.5%, with the applied methodology so far failing to contribute to higher

  6. Assessing relationships between state and local public health organizations: evidence from the NACCHO 2008 profile of local health departments.

    PubMed

    Parker, Andrew M; Shelton, Shoshana R; Morganti, Kristy Gonzalez; Nelson, Christopher

    2012-01-01

    Public health systems vary by degree of centralization, reflecting the distribution of authority, responsibility, and effort between state and local public health agencies. We analyzed data from the 2008 National Association of City and County Health Officials Profile of Local Health Departments survey, and propose an improved composite measure of centralization that can be computed for all local health departments within a state, as opposed to a single state respondent, as done in 1998. While most states' structures (79.5%) are decentralized, the new measure presents a continuum from highly decentralized to highly centralized. The measure was internally consistent (Cronbach α = .87) and correlated somewhat strongly with the centralization classification from the 1998 survey (Kendall's τ correlation = .62, P < .001), suggesting that a stable centralization construct can be reliably determined. This new centralization variable can facilitate more nuanced studies of public health systems, and inform policy design and implementation.

  7. Assessing Weather-Yield Relationships in Rice at Local Scale Using Data Mining Approaches.

    PubMed

    Delerce, Sylvain; Dorado, Hugo; Grillon, Alexandre; Rebolledo, Maria Camila; Prager, Steven D; Patiño, Victor Hugo; Garcés Varón, Gabriel; Jiménez, Daniel

    2016-01-01

    Seasonal and inter-annual climate variability have become important issues for farmers, and climate change has been shown to increase them. Simultaneously farmers and agricultural organizations are increasingly collecting observational data about in situ crop performance. Agriculture thus needs new tools to cope with changing environmental conditions and to take advantage of these data. Data mining techniques make it possible to extract embedded knowledge associated with farmer experiences from these large observational datasets in order to identify best practices for adapting to climate variability. We introduce new approaches through a case study on irrigated and rainfed rice in Colombia. Preexisting observational datasets of commercial harvest records were combined with in situ daily weather series. Using Conditional Inference Forest and clustering techniques, we assessed the relationships between climatic factors and crop yield variability at the local scale for specific cultivars and growth stages. The analysis showed clear relationships in the various location-cultivar combinations, with climatic factors explaining 6 to 46% of spatiotemporal variability in yield, and with crop responses to weather being non-linear and cultivar-specific. Climatic factors affected cultivars differently during each stage of development. For instance, one cultivar was affected by high nighttime temperatures in the reproductive stage but responded positively to accumulated solar radiation during the ripening stage. Another was affected by high nighttime temperatures during both the vegetative and reproductive stages. Clustering of the weather patterns corresponding to individual cropping events revealed different groups of weather patterns for irrigated and rainfed systems with contrasting yield levels. Best-suited cultivars were identified for some weather patterns, making weather-site-specific recommendations possible. This study illustrates the potential of data mining for

  8. Assessing Weather-Yield Relationships in Rice at Local Scale Using Data Mining Approaches

    PubMed Central

    Delerce, Sylvain; Dorado, Hugo; Grillon, Alexandre; Rebolledo, Maria Camila; Prager, Steven D.; Patiño, Victor Hugo; Garcés Varón, Gabriel; Jiménez, Daniel

    2016-01-01

    Seasonal and inter-annual climate variability have become important issues for farmers, and climate change has been shown to increase them. Simultaneously farmers and agricultural organizations are increasingly collecting observational data about in situ crop performance. Agriculture thus needs new tools to cope with changing environmental conditions and to take advantage of these data. Data mining techniques make it possible to extract embedded knowledge associated with farmer experiences from these large observational datasets in order to identify best practices for adapting to climate variability. We introduce new approaches through a case study on irrigated and rainfed rice in Colombia. Preexisting observational datasets of commercial harvest records were combined with in situ daily weather series. Using Conditional Inference Forest and clustering techniques, we assessed the relationships between climatic factors and crop yield variability at the local scale for specific cultivars and growth stages. The analysis showed clear relationships in the various location-cultivar combinations, with climatic factors explaining 6 to 46% of spatiotemporal variability in yield, and with crop responses to weather being non-linear and cultivar-specific. Climatic factors affected cultivars differently during each stage of development. For instance, one cultivar was affected by high nighttime temperatures in the reproductive stage but responded positively to accumulated solar radiation during the ripening stage. Another was affected by high nighttime temperatures during both the vegetative and reproductive stages. Clustering of the weather patterns corresponding to individual cropping events revealed different groups of weather patterns for irrigated and rainfed systems with contrasting yield levels. Best-suited cultivars were identified for some weather patterns, making weather-site-specific recommendations possible. This study illustrates the potential of data mining for

  9. Reversed-phase liquid chromatographic retention and membrane activity relationships of local anesthetics.

    PubMed

    Tsuchiya, Hironori; Mizogami, Maki; Takakura, Ko

    2005-05-06

    The chromatographic retention and membrane activity relationships of local anesthetics were studied to address the possible mechanisms for structure specificity and inflammation-associated decrease of their effects. Five representative drugs (3 mM for each) were reacted with 1,2-dipalmitoyl-sn-glycero-3-phosphocholine liposomes in 25 mM potassium phosphate buffer (pH 5.9-7.9, containing 100 mM NaCl and 0.1 mM EDTA) for 10 min at 37 degrees C and the membrane fluidity changes were analyzed by measuring fluorescence polarization with 1,6-diphenyl-1,3,5-hexatriene. Their capacity factors were determined on octadecyl-, octyl- and phenyl-bonded silica columns with a mobile phase consisting of 25 mM potassium phosphate buffer (pH 5.9-7.9, containing 100 mM NaCl and 0.1 mM EDTA)-methanol (30:70, v/v) at a flow rate of 1.0 ml/min and at a column temperature of 37 degrees C and diode-array detection. Mepivacaine, prilocaine, lidocaine, ropivacaine and bupivacaine fluidized membranes in increasing order of intensity, which agreed with their clinical potency. The relative degree of membrane fluidization correlated with that of retention on an octadecyl stationary phase more significantly than the other phases. Both membrane-fluidizing effects and capacity factors decreased by lowering the reaction and mobile phase pH, being consistent with the hypothesis that anesthetic potency is reduced in inflammation because of tissue acidity. Reversed-phase liquid chromatography appears to be useful for estimating the structure-specific and pH-dependent membrane-fluidizing effects of local anesthetics.

  10. Application of ISO 9000 Series Quality Management Standards at a Higher Education Institution: A Case of Lithuanian Maritime College

    ERIC Educational Resources Information Center

    Sencila, Viktoras; Skipariene, Ingrida

    2007-01-01

    The European education standards assurance and pursuit of quality in education have been announced as strategic aims of the Lithuanian education system in the light of new challenges the society is facing and opportunities offered by democracy, development of market economy and globalization. One of the ways to achieve the aims mentioned above is…

  11. The relationship between local scalp skin temperature and cutaneous perfusion during scalp cooling.

    PubMed

    Janssen, Francis-Paul E M; Rajan, Vinayakrishnan; Steenbergen, Wiendelt; van Leeuwen, Gerard M J; van Steenhoven, Anton A

    2007-08-01

    Cooling the scalp during administration of chemotherapy can prevent hair loss. It reduces both skin blood flow and hair follicle temperature, thus affecting drug supply and drug effect in the hair follicle. The extent to which these mechanisms contribute to the hair preservative effect of scalp cooling remains unknown. The purpose of this study was to establish a relationship between local scalp skin temperature and cutaneous blood flow during scalp cooling. We measured skin temperature and cutaneous perfusion during a cooling and re-warming experiment. Experiments on a single subject showed that the measurements were reproducible and that the response was identical for the two positions that were measured. Inter-subject variability was investigated on nine subjects. We found that for the first 10 degrees C of cooling, perfusion of the scalp skin decreases to below 40%. Perfusion can be further reduced to below 30% by a few degrees more cooling, but a plateau is reached after that. We found that a generally accepted relation in thermal physiology between temperature and perfusion (i.e. Q(10) relation) does not describe the data well, but we found an alternative relation that describes the average behavior significantly better.

  12. Relationship between the transition frequency of local fluid flow and the peak frequency of attenuation

    NASA Astrophysics Data System (ADS)

    Cao, Cheng-Hao; Zhang, Hong-Bing; Pan, Yi-Xin; Teng, Xin-Bao

    2016-03-01

    Local fluid flow (LFF) at the mesoscopic scale is the main dissipation mechanism of seismic waves in heterogeneous porous media within the seismic frequency band. LFF is easily influenced by the structure and boundary conditions of the porous media, which leads to different behaviors of the peak frequency of attenuation. The associated transition frequency can provide detailed information about the trend of LFF; therefore, research on the transition frequency of LFF and its relationship with the peak frequency of the corresponding attenuation (i.e., inverse of quality factor) facilitates the detailed understanding of the effect of inner structures and boundary conditions in porous media. In this study, we firstly obtain the transition frequency of fluid flux based on Biot's theory of poroelasticity and the fast Fourier transform algorithm in a sample containing one repeating unit cell (RUC). We then analyze changes of these two frequencies in porous media with different porous properties. Finally, we extend our analysis to the influence of the undrained boundary condition on the transition frequency and peak frequency in porous media with multiple RUCs. This setup can facilitate the understanding of the effect from the undrained boundary condition. Results demonstrate that these two frequencies have the same trend at low water saturation, but amplitude variations differ between the frequencies as the amount of saturation increases. However, for cases of high water saturation, both the trend and the amplitude variation of these two frequencies fit well with each other.

  13. PISA Test Items and School-Based Examinations in Greece: Exploring the Relationship between Global and Local Assessment Discourses

    ERIC Educational Resources Information Center

    Anagnostopoulou, Kyriaki; Hatzinikita, Vassilia; Christidou, Vasilia; Dimopoulos, Kostas

    2013-01-01

    The paper explores the relationship of the global and the local assessment discourses as expressed by Programme for International Student Assessment (PISA) test items and school-based examinations, respectively. To this end, the paper compares PISA test items related to living systems and the context of life, health, and environment, with Greek…

  14. Comparative analysis of local and consensus quantitative structure-activity relationship approaches for the prediction of bioconcentration factor.

    PubMed

    Piir, G; Sild, S; Maran, U

    2013-01-01

    Quantitative structure-activity relationships (QSARs) are broadly classified as global or local, depending on their molecular constitution. Global models use large and diverse training sets covering a wide range of chemical space. Local models focus on smaller structurally or chemically similar subsets that are conventionally selected by human experts or alternatively using clustering analysis. The current study focuses on the comparative analysis of different clustering algorithms (expectation-maximization, K-means and hierarchical) for seven different descriptor sets as structural characteristics and two rule-based approaches to select subsets for designing local QSAR models. A total of 111 local QSAR models are developed for predicting bioconcentration factor. Predictions from local models were compared with corresponding predictions from the global model. The comparison of coefficients of determination (r(2)) and standard deviations for local models with similar subsets from the global model show improved prediction quality in 97% of cases. The descriptor content of derived QSARs is discussed and analyzed. Local QSAR models were further consolidated within the framework of consensus approach. All different consensus approaches increased performance over the global and local models. The consensus approach reduced the number of strongly deviating predictions by evening out prediction errors, which were produced by some local QSARs.

  15. Relationship of edge localized mode burst times with divertor flux loop signal phase in JET

    SciTech Connect

    Chapman, S. C.; Dendy, R. O.; Todd, T. N.; Webster, A. J.; Morris, J.; Watkins, N. W.; Calderon, F. A.

    2014-06-15

    A phase relationship is identified between sequential edge localized modes (ELMs) occurrence times in a set of H-mode tokamak plasmas to the voltage measured in full flux azimuthal loops in the divertor region. We focus on plasmas in the Joint European Torus where a steady H-mode is sustained over several seconds, during which ELMs are observed in the Be II emission at the divertor. The ELMs analysed arise from intrinsic ELMing, in that there is no deliberate intent to control the ELMing process by external means. We use ELM timings derived from the Be II signal to perform direct time domain analysis of the full flux loop VLD2 and VLD3 signals, which provide a high cadence global measurement proportional to the voltage induced by changes in poloidal magnetic flux. Specifically, we examine how the time interval between pairs of successive ELMs is linked to the time-evolving phase of the full flux loop signals. Each ELM produces a clear early pulse in the full flux loop signals, whose peak time is used to condition our analysis. The arrival time of the following ELM, relative to this pulse, is found to fall into one of two categories: (i) prompt ELMs, which are directly paced by the initial response seen in the flux loop signals; and (ii) all other ELMs, which occur after the initial response of the full flux loop signals has decayed in amplitude. The times at which ELMs in category (ii) occur, relative to the first ELM of the pair, are clustered at times when the instantaneous phase of the full flux loop signal is close to its value at the time of the first ELM.

  16. Patterns of Spontaneous Local Network Activity in Developing Cerebral Cortex: Relationship to Adult Cognitive Function.

    PubMed

    Peinado, Alejandro; Abrams, Charles K

    2015-01-01

    Detecting neurodevelopμental disorders of cognition at the earliest possible stages could assist in understanding them mechanistically and ultimately in treating them. Finding early physiological predictors that could be visualized with functional neuroimaging would represent an important advance in this regard. We hypothesized that one potential source of physiological predictors is the spontaneous local network activity prominent during specific periods in development. To test this we used calcium imaging in brain slices and analyzed variations in the frequency and intensity of this early activity in one area, the entorhinal cortex (EC), in order to correlate early activity with level of cognitive function later in life. We focused on EC because of its known role in different types of cognitive processes and because it is an area where spontaneous activity is prominent during early postnatal development in rodent models of cortical development. Using rat strains (Long-Evans, Wistar, Sprague-Dawley and Brattleboro) known to differ in cognitive performance in adulthood we asked whether neonatal animals exhibit corresponding strain-related differences in EC spontaneous activity. Our results show significant differences in this activity between strains: compared to a high cognitive-performing strain, we consistently found an increase in frequency and decrease in intensity in neonates from three lower performing strains. Activity was most different in one strain considered a model of schizophrenia-like psychopathology. While we cannot necessarily infer a causal relationship between early activity and adult cognition our findings suggest that the pattern of spontaneous activity in development could be an early predictor of a developmental trajectory advancing toward sub-optimal cognitive performance in adulthood. Our results further suggest that the strength of dopaminergic signaling, by setting the balance between excitation and inhibition, is a potential underlying

  17. Defining the Relationship between Seismicity and Deformation at Regional and Local Scales

    NASA Astrophysics Data System (ADS)

    Williams, Nneka Njeri Akosua

    In this thesis, I use source inversion methods to improve understanding of crustal deformation along the Nyainquentanglha (NQTL) Detachment in Southern Tibet and the Piceance Basin in northwestern Colorado. Broadband station coverage in both regions is sparse, necessitating the development of innovative approaches to source inversion for the purpose of studying local earthquakes. In an effort to study the 2002-2003 earthquake swarm and the 2008 M w 6.3 Damxung earthquake and aftershocks that occurred in the NQTL region, we developed a single station earthquake location inversion method called the SP Envelope method, to be used with data from LHSA at Lhasa, a broadband seismometer located 75 km away. A location is calculated by first rotating the seismogram until the azimuth at which the envelope of the P-wave arrival on the T-component is smallest (its great circle path) is found. The distance at which to place the location along this azimuth is measured by calculating the S-P distance from arrivals on the seismogram. When used in conjunction with an existing waveform modeling based source inversion method called Cut and Paste (CAP), a catalog of 40 regional earthquakes was generated. From these 40 earthquakes, a catalog of 30 earthquakes with the most certain locations was generated to study the relationship of seismicity and NQTL region faults mapped in Google Earth™ and in Armijo et al., 1986 and Kapp et al., 2005. Using these faults and focal mechanisms, a fault model of the NQTL Region was generated using GOCAD, a 3D modeling suite. By studying the relationship of modeled faults to mapped fault traces at the surface, the most likely fault slip plane was chosen. These fault planes were then used to calculate slip vectors and a regional bulk stress tensor, with respect to which the low-angle NQTL Detachment was found to be badly misoriented. The formation of low-angle normal faults is inconsistent with the Anderson Theory of faulting, and the presence of the

  18. The relationship between regional and local species diversity in marine benthic communities: A global perspective

    PubMed Central

    Witman, Jon D.; Etter, Ron J.; Smith, Franz

    2004-01-01

    The number of species coexisting in ecological communities must be a consequence of processes operating on both local and regional scales. Although a great deal of experimental work has been devoted to local causes of diversity, little is known about the effects of regional processes on local diversity and how they contribute to global diversity patterns in marine systems. We tested the effects of latitude and the richness of the regional species pool on the species richness of local epifaunal invertebrate communities by sampling the diversity of local sites in 12 independent biogeographic regions from 62°S to 63°N latitude. Both regional and local species richness displayed significant unimodal patterns with latitude, peaking at low latitudes and decreasing toward high latitudes. The latitudinal diversity gradient was represented at the scale of local sites because local species richness was positively and linearly related to regional species richness. The richness of the regional species pool explained 73-76% of local species richness. On a global scale, the extent of regional influence on local species richness was nonrandom—the proportion of regional biota represented in local epifaunal communities increased significantly from low to high latitudes. The strong effect of the regional species pool implies that patterns of local diversity in temperate, tropical, and high-latitude marine benthic communities are influenced by processes operating on larger spatiotemporal scales than previously thought. PMID:15501917

  19. Genetic diversity and phylogenetic relationships in local cattle breeds of Senegal based on autosomal microsatellite markers

    PubMed Central

    Ndiaye, Ndèye Penda; Sow, Adama; Dayo, Guiguigbaza-Kossigan; Ndiaye, Saliou; Sawadogo, Germain Jerôme; Sembène, Mbacké

    2015-01-01

    Aim: In Senegal, uncontrolled cross-breeding of cattle breeds and changes in production systems are assumed to lead to an increase of gene flow between populations. This might constitute a relevant threat to livestock improvement. Therewith, this study was carried out to assess the current genetic diversity and the phylogenetic relationships of the four native Senegalese cattle breeds (Gobra zebu, Maure zebu, Djakoré, and N’Dama). Methods: Genomic DNA was isolated from blood samples of 120 unrelated animals collected from three agro-ecological areas of Senegal according to their phenotypic traits. Genotyping was done using 11 specific highly polymorphic microsatellite makers recommended by Food and Agriculture Organization. The basic measures of genetic variation and phylogenetic trees were computed using bioinformatics’ software. Results: A total of 115 alleles were identified with a number of alleles (Na) at one locus ranging from 6 to 16. All loci were polymorphic with a mean polymorphic information content of 0.76. The mean allelic richness (Rs) lay within the narrow range of 5.14 in N’Dama taurine to 6.10 in Gobra zebu. While, the expected heterozygosity (HE) per breed was high in general with an overall mean of 0.76±0.04. Generally, the heterozygote deficiency (FIS) of 0.073±0.026 was relatively due to inbreeding among these cattle breeds or the occurrence of population substructure. The high values of allelic and gene diversity showed that Senegalese native cattle breeds represented an important reservoir of genetic variation. The genetic distances and clustering trees concluded that the N’Dama cattle were most distinct among the investigated cattle populations. So, the principal component analyses showed qualitatively that there was an intensive genetic admixture between the Gobra zebu and Maure zebu breeds. Conclusions: The broad genetic diversity in Senegalese cattle breeds will allow for greater opportunities for improvement of productivity

  20. Exploring the relationship between vibrational mode locality and coupling using constrained optimization

    NASA Astrophysics Data System (ADS)

    Molina, Andrew; Smereka, Peter; Zimmerman, Paul M.

    2016-03-01

    The use of alternate coordinate systems as a means to improve the efficiency and accuracy of anharmonic vibrational structure analysis has seen renewed interest in recent years. While normal modes (which diagonalize the mass-weighted Hessian matrix) are a typical choice, the delocalized nature of this basis makes it less optimal when anharmonicity is in play. When a set of modes is not designed to treat anharmonicity, anharmonic effects will contribute to inter-mode coupling in an uncontrolled fashion. These effects can be mitigated by introducing locality, but this comes at its own cost of potentially large second-order coupling terms. Herein, a method is described which partially localizes vibrations to connect the fully delocalized and fully localized limits. This allows a balance between the treatment of harmonic and anharmonic coupling, which minimizes the error that arises from neglected coupling terms. Partially localized modes are investigated for a range of model systems including a tetramer of hydrogen fluoride, water dimer, ethene, diphenylethane, and stilbene. Generally, partial localization reaches ˜75% of maximal locality while introducing less than ˜30% of the harmonic coupling of the fully localized system. Furthermore, partial localization produces mode pairs that are spatially separated and thus weakly coupled to one another. It is likely that this property can be exploited in the creation of model Hamiltonians that omit the coupling parameters of the distant (and therefore uncoupled) pairs.

  1. Evaluation of quantitative structure-activity relationship modeling strategies: local and global models.

    PubMed

    Helgee, Ernst Ahlberg; Carlsson, Lars; Boyer, Scott; Norinder, Ulf

    2010-04-26

    A thorough comparison between different QSAR modeling strategies is presented. The comparison is conducted for local versus global modeling strategies, risk assessment, and computational cost. The strategies are implemented using random forests, support vector machines, and partial least squares. Results are presented for simulated data, as well as for real data, generally indicating that a global modeling strategy is preferred over a local strategy. Furthermore, the results also show that there is an pronounced risk and a comparatively high computational cost when using the local modeling strategies.

  2. Testing the relationship between local cue-response patterns and the global structure of communication behaviour.

    PubMed

    Taylor, Paul J; Donald, Ian

    2007-06-01

    A central assumption of negotiation research is that organized sequences of cues and responses underlie the dimensions and constructs found to structure interaction. We empirically tested this assumption using a new 'proximity' coefficient, which measures the global interrelationships among behaviours based on their intrinsic local organization within an interaction sequence. An analysis of sequences from 21 hostage negotiations showed that local cue-response dependencies are organized in a way that corresponds with an established structural model of communication. Further analysis of case-specific coefficients showed that criminal, political and domestic incidents involve very different cue-response dynamics, with criminal incidents dividing into two distinct types of interaction. The importance of the proximity concept for unifying local and global accounts of negotiation behaviour, and the avenues of research made possible by the proximity coefficient, are discussed.

  3. Functional Localization and Double Dissociations: The Relationship between Internal Structure and Behavior

    ERIC Educational Resources Information Center

    Medler, D.A.; Dawson, M.R.W.; Kingstone, A.

    2005-01-01

    Lesioning studies are often used in cognitive neuroscience to make inferences about the architecture of cognition. Recently, computational models have been used to address some of the underlying assumptions-such as modularity and locality-often implicitly used when interpreting lesion data. In this article, we explore the ''functional…

  4. The Local Construction of the Asymmetrical Power Relationship in Teamwork among Engineers

    ERIC Educational Resources Information Center

    Vickers, Caroline H.

    2010-01-01

    The purpose of this article is to examine local, interactional processes associated with the construction of power asymmetries in collaborative teamwork among engineering students. To explore the construction of power asymmetries at the micro-interactional level, this article examines a corpus consisting of about 150,000 words in which seven teams…

  5. The Economic Relationship between Institutions of Higher Education and Their Local Communities.

    ERIC Educational Resources Information Center

    Fink, Ira

    1980-01-01

    Aspects of the economic impact of colleges and universities on the communities in which they are located are examined. These include revenue sources, cash flow, local expenditures, banking, municipal services, taxes, alteration of neighborhoods, enrollment patterns, employment patterns and needs, housing, lifestyles, and gains in human capital.…

  6. "Critical Friends": Exploring Arm's Length Actor Relationships to Local Government in Education

    ERIC Educational Resources Information Center

    Exley, Sonia

    2016-01-01

    Discussions charting the changing role of local government in education have often focused extensively on "concrete" policy changes over time, but have provided less detail on the contribution to changing power relations of less tangible shifts. Drawing on Foucauldian notions of discourse and governmentality, in this paper, detailed…

  7. Alzheimer's disease can spare local metacognition despite global anosognosia: revisiting the confidence-accuracy relationship in episodic memory.

    PubMed

    Gallo, David A; Cramer, Stefanie J; Wong, Jessica T; Bennett, David A

    2012-07-01

    Alzheimer's disease (AD) can impair metacognition in addition to more basic cognitive functions like memory. However, while global metacognitive inaccuracies are well documented (i.e., low deficit awareness, or anosognosia), the evidence is mixed regarding the effects of AD on local or task-based metacognitive judgments. Here we investigated local metacognition with respect to the confidence-accuracy relationship in episodic memory (i.e., metamemory). AD and control participants studied pictures of common objects and their verbal labels, and then took forced-choice picture recollection tests using the verbal labels as retrieval cues. We found that item-based confidence judgments discriminated between accurate and inaccurate recollection responses in both groups, implicating relatively spared metamemory in AD. By contrast, there was evidence for global metacognitive deficiencies, as AD participants underestimated the severity of their everyday problems compared to an informant's assessment. Within the AD group, individual differences in global metacognition were related to recollection accuracy, and global metacognition for everyday memory problems was related to task-based metacognitive accuracy. These findings suggest that AD can spare the confidence-accuracy relationship in recollection tasks, and that global and local metacognition measures tap overlapping neuropsychological processes.

  8. The relationship of the local food environment with obesity: A systematic review of methods, study quality and results

    PubMed Central

    Cobb, Laura K; Appel, Lawrence J; Franco, Manuel; Jones-Smith, Jessica C; Nur, Alana; Anderson, Cheryl AM

    2015-01-01

    Objective To examine the relationship between local food environments and obesity and assess the quality of studies reviewed. Methods Systematic keyword searches identified studies from US and Canada that assessed the relationship of obesity to local food environments. We applied a quality metric based on design, exposure and outcome measurement, and analysis. Results We identified 71 studies representing 65 cohorts. Overall, study quality was low; 60 studies were cross-sectional. Associations between food outlet availability and obesity were predominantly null. Among non-null associations, we saw a trend toward inverse associations between supermarket availability and obesity (22 negative, 4 positive, 67 null) and direct associations between fast food and obesity (29 positive, 6 negative, 71 null) in adults. We saw direct associations between fast food availability and obesity in lower income children (12 positive, 7 null). Indices including multiple food outlets were most consistently associated with obesity in adults (18 expected, 1 not expected, 17 null). Limiting to higher quality studies did not affect results. Conclusions Despite the large number of studies, we found limited evidence for associations between local food environments and obesity. The predominantly null associations should be interpreted cautiously due to the low quality of available studies. PMID:26096983

  9. Alzheimer’s Disease Can Spare Local Metacognition Despite Global Anosognosia: Revisiting the Confidence-Accuracy Relationship in Episodic Memory

    PubMed Central

    Gallo, David A.; Cramer, Stefanie J.; Wong, Jessica T.; Bennett, David A.

    2012-01-01

    Alzheimer’s Disease (AD) can impair metacognition in addition to more basic cognitive functions like memory. However, while global metacognitive inaccuracies are well documented (i.e., low deficit awareness, or anosognosia), the evidence is mixed regarding the effects of AD on local or task-based metacognitive judgments. Here we investigated local metacognition with respect to the confidence-accuracy relationship in episodic memory (i.e., metamemory). AD and control participants studied pictures of common objects and their verbal labels, and then took forced-choice picture recollection tests using the verbal labels as retrieval cues. We found that item-based confidence judgments discriminated between accurate and inaccurate recollection responses in both groups, implicating relatively spared metamemory in AD. By contrast, there was evidence for global metacognitive deficiencies, as AD participants underestimated the severity of their everyday problems compared to an informant’s assessment. Within the AD group, individual differences in global metacognition were related to recollection accuracy, and global metacognition for everyday memory problems was related to task-based metacognitive accuracy. These findings suggest that AD can spare the confidence-accuracy relationship in recollection tasks, and that global and local metacognition measures tap overlapping neuropsychological processes. PMID:22722068

  10. Do galaxy global relationships emerge from local ones? The SDSS IV MaNGA surface mass density-metallicity relation

    NASA Astrophysics Data System (ADS)

    Barrera-Ballesteros, Jorge K.; Heckman, Timothy M.; Zhu, Guangtun B.; Zakamska, Nadia L.; Sánchez, Sebastian F.; Law, David; Wake, David; Green, Jenny E.; Bizyaev, Dmitry; Oravetz, Daniel; Simmons, Audrey; Malanushenko, Elena; Pan, Kaike; Roman Lopes, Alexandre; Lane, Richard R.

    2016-12-01

    We present the stellar surface mass density versus gas metallicity (Σ*-Z) relation for more than 500 000 spatially resolved star-forming resolution elements (spaxels) from a sample of 653 disc galaxies included in the SDSS IV MaNGA survey. We find a tight relation between these local properties, with higher metallicities as the surface density increases. This relation extends over three orders of magnitude in the surface mass density and a factor of 4 in metallicity. We show that this local relationship can simultaneously reproduce two well-known properties of disc galaxies: their global mass-metallicity relationship and their radial metallicity gradients. We also find that the Σ*-Z relation is largely independent of the galaxy's total stellar mass and specific star formation rate (sSFR), except at low stellar mass and high sSFR. These results suggest that in the present-day universe local properties play a key role in determining the gas-phase metallicity in typical disc galaxies.

  11. Sound localization in a new-world frugivorous bat, Artibeus jamaicensis: acuity, use of binaural cues, and relationship to vision.

    PubMed

    Heffner, R S; Koay, G; Heffner, H E

    2001-01-01

    Passive sound-localization acuity and its relationship to vision were determined for the echolocating Jamaican fruit bat (Artibeus jamaicensis). A conditioned avoidance procedure was used in which the animals drank fruit juice from a spout in the presence of sounds from their right, but suppressed their behavior, breaking contact with the spout, whenever a sound came from their left, thereby avoiding a mild shock. The mean minimum audible angle for three bats for a 100-ms noise burst was 10 degrees-marginally superior to the 11.6 degrees threshold for Egyptian fruit bats and the 14 degrees threshold for big brown bats. Jamaican fruit bats were also able to localize both low- and high-frequency pure tones, indicating that they can use both binaural phase- and intensity-difference cues to locus. Indeed, their ability to use the binaural phase cue extends up to 6.3 kHz, the highest frequency so far for a mammal. The width of their field of best vision, defined anatomically as the width of the retinal area containing ganglion-cell densities at least 75% of maximum, is 34 degrees. This value is consistent with the previously established relationship between vision and hearing indicating that, even in echolocating bats, the primary function of passive sound localization is to direct the eyes to sound sources.

  12. Laterality of handgrip strength: age- and physical training-related changes in Lithuanian schoolchildren and conscripts.

    PubMed

    Tutkuviene, Janina; Schiefenhövel, Wulf

    2013-06-01

    Laterality in handgrip strength was assessed by analyzing dynamometric data of the right and left hand in three samples of Lithuanian boys and girls aged 7-20 years. In addition, the influence of general physical training on the laterality of handgrip strength was explored in a sample of conscripts. A negative secular trend in handgrip strength of schoolchildren has been detected since 1965, and with increasing age, right-handedness has become more pronounced. Children that were ambidextrous (by grip strength) showed negative deviations in physical status more often than their right- or left-handed peers. During one year of physical training, the conscripts had a larger increase in grip strength of the left than in the right hand, and a marked shift in handgrip laterality toward left-handed and ambidextrous individuals was observed. The different impact of schooling and physical training on handgrip strength laterality might partly explain variations in the prevalence of handedness in different societies with divergent cultures and lifestyles (e.g., more or less sedentary).

  13. Total Phenolic Content and Antimicrobial Activity of Different Lithuanian Propolis Solutions

    PubMed Central

    Ramanauskienė, Kristina; Inkėnienė, Asta Marija; Petrikaitė, Vilma; Briedis, Vitalis

    2013-01-01

    The manufacture of ethanol-free propolis solutions offers a broader application. A few trials with Lithuanian propolis have been conducted. The aims of the study are to manufacture propolis water and water-free solutions and evaluate the quality and antimicrobial activity of these solutions. The studied solutions containing 2.5%, 5%, and 10% propolis are prepared. As solvents, purified water, 70% v/v ethanol, 96.3% v/v ethanol, propylene glycol, and their systems were used. Determination of total levels of phenolic compounds (FAE mg/g) is based on colour oxidation-reduction reaction using Folin-Ciocalteu reagent under alkaline conditions and performed at 765 nm wavelength using UV spectrophotometer. The highest content of phenolic compounds was determined in solutions containing 10% propolis extracts, and the lowest amounts in 2.5% propolis extracts. The water extracted the lowest amount of phenolic compounds from crude propolis, ethanol extracted the highest amount, and propylene glycol ranked the middle position. It is determined that technological parameters (stirring, temperature) contribute to content of phenolic compounds. During microbiological study, MICs were determined. The studies showed that water extracted propolis solutions and solvents mixture did not inhibit the growth of the studied microorganisms, and propolis solutions in propylene glycol were found to have antimicrobial activity. PMID:23573156

  14. Total phenolic content and antimicrobial activity of different lithuanian propolis solutions.

    PubMed

    Ramanauskienė, Kristina; Inkėnienė, Asta Marija; Petrikaitė, Vilma; Briedis, Vitalis

    2013-01-01

    The manufacture of ethanol-free propolis solutions offers a broader application. A few trials with Lithuanian propolis have been conducted. The aims of the study are to manufacture propolis water and water-free solutions and evaluate the quality and antimicrobial activity of these solutions. The studied solutions containing 2.5%, 5%, and 10% propolis are prepared. As solvents, purified water, 70% v/v ethanol, 96.3% v/v ethanol, propylene glycol, and their systems were used. Determination of total levels of phenolic compounds (FAE mg/g) is based on colour oxidation-reduction reaction using Folin-Ciocalteu reagent under alkaline conditions and performed at 765 nm wavelength using UV spectrophotometer. The highest content of phenolic compounds was determined in solutions containing 10% propolis extracts, and the lowest amounts in 2.5% propolis extracts. The water extracted the lowest amount of phenolic compounds from crude propolis, ethanol extracted the highest amount, and propylene glycol ranked the middle position. It is determined that technological parameters (stirring, temperature) contribute to content of phenolic compounds. During microbiological study, MICs were determined. The studies showed that water extracted propolis solutions and solvents mixture did not inhibit the growth of the studied microorganisms, and propolis solutions in propylene glycol were found to have antimicrobial activity.

  15. Blood transfusions and local tumor recurrence in colorectal cancer. Evidence of a noncausal relationship.

    PubMed Central

    Busch, O R; Hop, W C; Marquet, R L; Jeekel, J

    1994-01-01

    OBJECTIVE. The authors analyzed the effect of blood transfusions on the pattern of colorectal cancer recurrence. BACKGROUND. Retrospective studies suggest that blood transfusions are associated with a poor prognosis in patients who undergo operations for colorectal malignancies. In a previously published, randomized trial, it was investigated whether autologous blood transfusions could overcome this putative detrimental effect. However, this did not appear to be the case. METHODS. In the current study, the authors analyzed the patterns of recurrence in 420 patients who underwent curative operations for colorectal cancer. RESULTS. Patients who did not require transfusions (N = 143) had significantly better disease-free survival than those who did need transfusions (N = 277); percentages at 4 years were 73% and 59%, respectively (p = 0.001). No difference was found between both groups in comparing cumulative percentages of patients having metastases; percentages at 4 years were 25% in the group that did not undergo transfusion and 27% in the transfused group. The percentage of cases having local recurrence, however, was significantly increased (p = 0.0006) in the transfused group as compared with the group that did not undergo transfusion; percentages at 4 years were 20% and 3%, respectively. The groups of patients receiving only allogeneic, only autologous, or both types of transfusions all had a significantly higher incidence of local recurrence than the patients who did not receive transfusions, but no differences were found between these three groups. CONCLUSIONS. These findings suggest that the association between blood transfusions and prognosis in colorectal cancer is a result of the circumstances that necessitate transfusions, leading to the development of local recurrences, but not of distant metastases. PMID:7986147

  16. Correlative infrared-electron nanoscopy reveals the local structure-conductivity relationship in zinc oxide nanowires

    NASA Astrophysics Data System (ADS)

    Stiegler, J. M.; Tena-Zaera, R.; Idigoras, O.; Chuvilin, A.; Hillenbrand, R.

    2012-10-01

    High-resolution characterization methods play a key role in the development, analysis and optimization of nanoscale materials and devices. Because of the various material properties, only a combination of different characterization techniques provides a comprehensive understanding of complex functional materials. Here we introduce correlative infrared-electron nanoscopy, a novel method yielding transmission electron microscope and infrared near-field images of one and the same nanostructure. While transmission electron microscopy provides structural information up to the atomic level, infrared near-field imaging yields nanoscale maps of chemical composition and conductivity. We demonstrate the method's potential by studying the relation between conductivity and crystal structure in ZnO nanowire cross-sections. The combination of infrared conductivity maps and the local crystal structure reveals a radial free-carrier gradient, which inversely correlates to the density of extended crystalline defects. Our method opens new avenues for studying the local interplay between structure, conductivity and chemical composition in widely different material systems.

  17. Values, animal symbolism, and human-animal relationships associated to two threatened felids in Mapuche and Chilean local narratives

    PubMed Central

    2013-01-01

    Background The Chilean temperate rainforest has been subjected to dramatic fragmentation for agriculture and forestry exploitation. Carnivore species are particularly affected by fragmentation and the resulting resource use conflicts with humans. This study aimed at understanding values and human-animal relationships with negatively perceived threatened carnivores through the disclosure of local stories and Mapuche traditional folktales. Methods Our mixed approach comprised the qualitative analysis of 112 stories on the kodkod cat (Leopardus guigna) and the puma (Puma concolor) collected by students (9-14 years) from 28 schools in the Araucania region within their family contexts, 10 qualitative in-depth interviews with indigenous Mapuche people, 35 traditional Mapuche legends, and the significance of naming found in ethnographic collections. Results We revealed a quasi-extinction of traditional tales in the current knowledge pool about pumas and kodkods, local anecdotes, however, were present in significant numbers. Values associated to both felids were manifold, ranging from negativistic to positive values. While pumas played an important role in people’s spirituality, negative mythological connotations persisted in kodkod stories. Four prominent relationships were derived: (1) Both felids represent threats to livestock, pumas even to life, (2) both felids are symbols for upcoming negative events, (3) pumas are spiritual creatures, and (4) kodkods are threatened by humans. Recommendations are provided for stimulating new ways of perceiving unpopular and threatened carnivores among those who live in vicinity to them. PMID:23764186

  18. Communication: Local structure-mobility relationships of confined fluids reverse upon supercooling.

    PubMed

    Bollinger, Jonathan A; Jain, Avni; Carmer, James; Truskett, Thomas M

    2015-04-28

    We examine the structural and dynamic properties of confined binary hard-sphere mixtures designed to mimic realizable colloidal thin films. Using computer simulations, governed by either Newtonian or overdamped Langevin dynamics, together with other techniques including a Fokker-Planck equation-based method, we measure the position-dependent and average diffusivities of particles along structurally isotropic and inhomogeneous dimensions of the fluids. At moderate packing fractions, local single-particle diffusivities normal to the direction of confinement are higher in regions of high total packing fraction; however, these trends are reversed as the film is supercooled at denser average packings. Auxiliary short-time measurements of particle displacements mirror data obtained for experimental supercooled colloidal systems. We find that average dynamics can be approximately predicted based on the distribution of available space for particle insertion across orders of magnitude in diffusivity regardless of the governing microscopic dynamics.

  19. The Australian Seismometers in Schools Project: Building relationships between scientists, schools and local enthusiasts

    NASA Astrophysics Data System (ADS)

    Balfour, N.; Sambridge, M.; O'Neill, C.

    2011-12-01

    The Australian Seismometers in Schools (SIS) programme is a four-year project (2011-2014) funded by the Education component of AuScope Australian Geophysical Observing System (AGOS). Over the next four years SIS will build a network of 40 seismometers installed in high schools across the nation to provide real-time monitoring of the Australian continent and raise awareness of geoscience through observing our dynamic earth in motion. The Australian Seismometers in Schools project aims to: Raise community awareness of regional earthquakes; Raise awareness of seismology and, more generally geoscience, as a field of study; Promote science as a possible career choice; Provide a tool to teachers to assist in teaching physics and earth science to high school students. Due to the expanse of Australia and remoteness of many communities we require local experts and enthusiasts get involved in the program to provide support and share their knowledge with schools. Students are required to look after their very own seismometer and in doing so be a part of a national science experiment. The project involves e-infrastructure consisting of an online education portal allowing real time access by students to earthquake recordings in their own and other schools. The data schools collect will be useful to researchers and could complement networks run by government and state agencies due to the high quality of the instruments. Long-term storage of data for research purposes will be aligned with community standards at internationally accessible and supported data management centres, such as IRIS. A growing community of institutional and individual volunteers is forming to support the program within their local state or territory. Over the duration of the project this partner network will significantly enhance the project through provision of technical or management expertise as well as promotion within the education sector.

  20. Relationship between Material Properties and Local Formability of DP980 Steels

    SciTech Connect

    Choi, Kyoo Sil; Soulami, Ayoub; Li, Dongsheng; Sun, Xin; Khaleel, Mohammad A.; Xu, Le; Barlat, Frederic

    2012-04-24

    A noticeable degree of inconsistent forming behaviors has been observed for the 1st generation advanced high strength steels (AHSS) in production, and they appear to be associated with the inherent microstructural-level inhomogeneities for various AHSS. This indicates that the basic material property requirements and screening methods currently used for the mild steels and high strength low alloys (HSLA) are no longer sufficient for qualifying today’s AHSS. In order to establish more relevant material acceptance criteria for AHSS, the fundamental understandings on key mechanical properties and microstructural features influencing the local formability of AHSS need to be developed. For this purpose, in this study, DP980 was selected as model steels and eight different types of DP980 sheet steels were acquired from various steel suppliers. Various experiments were then performed on the eight different DP980 steels such as chemical composition analysis, static tensile test, hole expansion test, channel forming test. Scanning electron microscope (SEM) pictures of the DP980 steels were also obtained, and image processing tools were then adopted to those SEM pictures in order to quantify their various microstructural features. The results show that all DP980 steels show large discrepancy in their performance and that the tensile properties and hole expansion properties of these steels do not correlate with their local formability. According to the results up to date, it is not possible to correlate the microstructural features alone to the macroscopically measured deformation behaviors. In addition to image analysis, other experiments (i.e., nano-indentation test) are also planned to quantify the individual phase properties of the various DP steels.

  1. Relationships between spike-free local field potentials and spike timing in human temporal cortex

    PubMed Central

    Zanos, Theodoros P.; Marmarelis, Vasilis Z.; Ojemann, George A.; Fetz, Eberhard E.

    2012-01-01

    Intracortical recordings comprise both fast events, action potentials (APs), and slower events, known as local field potentials (LFPs). Although it is believed that LFPs mostly reflect local synaptic activity, it is unclear which of their signal components are most closely related to synaptic potentials and would therefore be causally related to the occurrence of individual APs. This issue is complicated by the significant contribution from AP waveforms, especially at higher LFP frequencies. In recordings of single-cell activity and LFPs from the human temporal cortex, we computed quantitative, nonlinear, causal dynamic models for the prediction of AP timing from LFPs, at millisecond resolution, before and after removing AP contributions to the LFP. In many cases, the timing of a significant number of single APs could be predicted from spike-free LFPs at different frequencies. Not surprisingly, model performance was superior when spikes were not removed. Cells whose activity was predicted by the spike-free LFP models generally fell into one of two groups: in the first group, neuronal spike activity was associated with specific phases of low LFP frequencies, lower spike activity at high LFP frequencies, and a stronger linear component in the spike-LFP model; in the second group, neuronal spike activity was associated with larger amplitude of high LFP frequencies, less frequent phase locking, and a stronger nonlinear model component. Spike timing in the first group was better predicted by the sign and level of the LFP preceding the spike, whereas spike timing in the second group was better predicted by LFP power during a certain time window before the spike. PMID:22157112

  2. Localized surface plasmon resonance induced structure-property relationships of metal nanostructures

    NASA Astrophysics Data System (ADS)

    Vilayurganapathy, Subramanian

    The confluence of nanotechnology and plasmonics has led to new and interesting phenomena. The industrial need for fast, efficient and miniature devices which constantly push the boundaries on device performance tap into the happy marriage between these diverse fields. Designing devices for real life application that give superior performance when compared with existing ones are enabled by a better understanding of their structure-property relationships. Among all the design constraints, without doubt, the shape and size of the nanostructure along with the dielectric medium surrounding it has the maximum influence on the response and thereby the performance of the device. Hence a careful study of the above mentioned parameters is of utmost importance in designing efficient devices. In this dissertation, we synthesize and study the optical properties of nanostructures of different shapes and size. In particular, we estimated the plasmonic near field enhancement via surface-enhanced Raman scattering (SERS) and 2-photon Photoemission electron microscopy (2P-PEEM). We synthesized the nanostructures using four different techniques. One synthesis technique, the thermal growth method was employed to grow interesting Ag and Au nanostructures on Si. The absence of toxic chemicals during nanostructure synthesis via the thermal growth technique opens up myriad possibilities for applications in the fields of biomedical science, bioengineering, drug delivery among others along with the huge advantage of being environment friendly. The other three synthesis techniques (ion implantation, Electrodeposition and FIB lithography) were chosen with the specific goal of designing novel plasmonic metal, metal hybrid nanostructures as photocathode materials in next generation light sources. The synthesis techniques for these novel nanostructures were dictated by the requirement of high quantum efficiency, robustness under constant irradiation and coherent unidirectional electron emission

  3. Relationship between occupational exposure to lead and local arterial stiffness and left ventricular diastolic function in individuals with arterial hypertension

    SciTech Connect

    Poreba, Rafal; Gac, Pawel; Poreba, Malgorzata; Antonowicz-Juchniewicz, Jolanta; Andrzejak, Ryszard

    2011-08-01

    Relationship between occupational exposure to lead and frequency of complications in persons with arterial hypertension has been poorly investigated. This study aimed at evaluation of the relationship between occupational exposure to lead and manifestation of an increased local arterial stiffness and left ventricular diastolic dysfunction. The studies included 105 men (mean age: 44.47 {+-} 9.12 years) with arterial hypertension, treated with hypotensive drugs: group I - men occupationally exposed to lead (n = 53), and group II - men not exposed to lead (n = 52). In echocardiographic examination, the left ventricular diastolic dysfunction was diagnosed significantly more frequently in group I than in group II. In eTracking examination mean values of stiffness parameter ({beta}), augmentation index (AI) and one-point pulse wave velocity (PWV-{beta}) were significantly higher and mean values of arterial compliance (AC) were significantly lower in group I than in group II. The logistic regression showed that in the group of persons with arterial hypertension occupationally exposed to lead a more advanced age, higher blood lead concentration and higher mean values of augmentation index represent independent risk factors of left ventricular diastolic dysfunction. The multifactorial regression showed that amongst persons with arterial hypertension occupationally exposed to lead higher blood zinc protoporphyrin concentration, a more advanced age and higher value of body mass index (BMI) represent independent risk factors of an increased local arterial stiffness. In summary, we should note that in the group of persons with arterial hypertension occupationally exposed to lead the study has demonstrated a significantly more frequent manifestation of left ventricular diastolic dysfunction and an increase in local arterial stiffness. - Highlights: > Amongst persons with AH exposed to Pb higher ZnPP represent independent risk factor of increased local arterial stiffness

  4. Localization of the primordial vomeronasal organ and its relationship to the associated gland in lungfish.

    PubMed

    Nakamuta, Shoko; Nakamuta, Nobuaki; Taniguchi, Kazumi; Taniguchi, Kazuyuki

    2013-04-01

    The lungfish, the closest fish to tetrapods, has two types of sensory epithelia in the olfactory organ: the lamellar olfactory epithelium and the recess epithelium. The former resembles the olfactory epithelium of ordinary teleosts and the latter resembles the vomeronasal organ of tetrapods with respect to the G-protein expressions and the morphological properties of olfactory receptor cells. In contrast to the lamellar olfactory epithelium covering the surface of olfactory lamella, the recess epithelium, together with the glandular epithelium, lines the recesses at the base of olfactory lamellae and is separated from the surrounding tissues by nonsensory epithelium. In the present study, we examined the distribution of these recesses and the relationship between the recess epithelium and the associated gland in the nasal sac of lungfish. We found that the posterior part of the nasal sac contained more recesses than the anterior one, and the medial one contained more recesses than the lateral one. In addition, virtually all recesses consisted of both the recess epithelium and the glandular epithelium. Furthermore, the glandular epithelium was invariably situated proximal to the midline raphe of the nasal sac, and the recess epithelium distal to it. Possible roles of the recess epithelium and the glandular epithelium are discussed.

  5. Relationship between local structure and relaxation in out-of-equilibrium glassy systems

    PubMed Central

    Cubuk, Ekin D.; Kaxiras, Efthimios; Liu, Andrea J.

    2017-01-01

    The dynamical glass transition is typically taken to be the temperature at which a glassy liquid is no longer able to equilibrate on experimental timescales. Consequently, the physical properties of these systems just above or below the dynamical glass transition, such as viscosity, can change by many orders of magnitude over long periods of time following external perturbation. During this progress toward equilibrium, glassy systems exhibit a history dependence that has complicated their study. In previous work, we bridged the gap between structure and dynamics in glassy liquids above their dynamical glass transition temperatures by introducing a scalar field called “softness,” a quantity obtained using machine-learning methods. Softness is designed to capture the hidden patterns in relative particle positions that correlate strongly with dynamical rearrangements of particle positions. Here we show that the out-of-equilibrium behavior of a model glass-forming system can be understood in terms of softness. To do this we first demonstrate that the evolution of behavior following a temperature quench is a primarily structural phenomenon: The structure changes considerably, but the relationship between structure and dynamics remains invariant. We then show that the relaxation time can be robustly computed from structure as quantified by softness, with the same relation holding both in equilibrium and as the system ages. Together, these results show that the history dependence of the relaxation time in glasses requires knowledge only of the softness in addition to the usual state variables. PMID:28028217

  6. Relationship between local structure and relaxation in out-of-equilibrium glassy systems

    NASA Astrophysics Data System (ADS)

    Schoenholz, Samuel S.; Cubuk, Ekin D.; Kaxiras, Efthimios; Liu, Andrea J.

    2017-01-01

    The dynamical glass transition is typically taken to be the temperature at which a glassy liquid is no longer able to equilibrate on experimental timescales. Consequently, the physical properties of these systems just above or below the dynamical glass transition, such as viscosity, can change by many orders of magnitude over long periods of time following external perturbation. During this progress toward equilibrium, glassy systems exhibit a history dependence that has complicated their study. In previous work, we bridged the gap between structure and dynamics in glassy liquids above their dynamical glass transition temperatures by introducing a scalar field called “softness,” a quantity obtained using machine-learning methods. Softness is designed to capture the hidden patterns in relative particle positions that correlate strongly with dynamical rearrangements of particle positions. Here we show that the out-of-equilibrium behavior of a model glass-forming system can be understood in terms of softness. To do this we first demonstrate that the evolution of behavior following a temperature quench is a primarily structural phenomenon: The structure changes considerably, but the relationship between structure and dynamics remains invariant. We then show that the relaxation time can be robustly computed from structure as quantified by softness, with the same relation holding both in equilibrium and as the system ages. Together, these results show that the history dependence of the relaxation time in glasses requires knowledge only of the softness in addition to the usual state variables.

  7. The Relationship between Localized Subarachnoid Inflammation and Parenchymal Pathophysiology after Spinal Cord Injury

    PubMed Central

    Austin, James W.; Afshar, Mehdi

    2012-01-01

    Abstract Subarachnoid inflammation following spinal cord injury (SCI) can lead to the formation of localized subarachnoid scarring and the development of post-traumatic syringomyelia (PTS). While PTS is a devastating complication of SCI, its relative rarity (occurring symptomatically in about 5% of clinical cases), and lack of fundamental physiological insights, have led us to examine an animal model of traumatic SCI with induced arachnoiditis. We hypothesized that arachnoiditis associated with SCI would potentiate early parenchymal pathophysiology. To test this theory, we examined early spatial pathophysiology in four groups: (1) sham (non-injured controls), (2) arachnoiditis (intrathecal injection of kaolin), (3) SCI (35-g clip contusion/compression injury), and (4) PTS (intrathecal kaolin+SCI). Overall, there was greater parenchymal inflammation and scarring in the PTS group relative to the SCI group. This was demonstrated by significant increases in cytokine (IL-1α and IL-1β) and chemokine (MCP-1, GRO/KC, and MIP-1α) production, MPO activity, blood–spinal cord barrier (BSCB) permeability, and MMP-9 activity. However, parenchymal inflammatory mediator production (acute IL-1α and IL-1β, subacute chemokines), BSCB permeability, and fibrous scarring in the PTS group were larger than the sum of the SCI group and arachnoiditis group combined, suggesting that arachnoiditis does indeed potentiate parenchymal pathophysiology. Accordingly, these findings suggest that the development of arachnoiditis associated with SCI can lead to an exacerbation of the parenchymal injury, potentially impacting the outcome of this devastating condition. PMID:22655536

  8. Genotype-phenotype relationship for localization and age distribution of telangiectases in hereditary hemorrhagic telangiectasia.

    PubMed

    Letteboer, Tom G W; Mager, Hans-Jurgen; Snijder, Repke J; Lindhout, Dick; Ploos van Amstel, Hans-Kristian; Zanen, Pieter; Westermann, Kees J J

    2008-11-01

    Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease characterized by arteriovenous malformations (AVMs) ranging from telangiectases to larger AVMs. Mutations in two genes cause HHT; ENG (HHT1) and ACVRL1 (HHT2). Although the hallmark for clinical diagnosis is the presence of telangiectases, there are few publications reporting the relative distribution and frequency of these features between HHT1 and HHT2. Here, the results of such analysis of telangiectases in 268 patients with HHT1 and 130 patients with HHT2 are described. Localization of the telangiectases is reported, and patients were clustered by age to estimate the site prevalence for different age categories. We show that telangiectases of the nasal mucosa are present at a higher prevalence and start to appear earlier in life than those of the oral mucosa or dermal sites in patients with either HHT1 or HHT2. Oral and nasal mucosal telangiectases are present earlier in life in patients with HHT1 compared to patients with HHT2, whereas dermal lesions are more frequent and appear earlier in life in patients with HHT2. In patients with either HHT1 or HHT2, the number of sites affected increases with age. In patients with HHT1, more women than men had skin telangiectases, particularly on the face. These results confirm that the frequency of AVMs differ between patients with HHT1 and HHT2, and that these differences can be detected on physical examination.

  9. Relationship between edge localized mode severity and electron transport in the National Spherical Torus Experiment

    SciTech Connect

    Tritz, K.; Stutman, D.; Delgado-Aparicio, L.; Finkenthal, M.; Kaye, S.; Bell, R.; LeBlanc, B.; Mazzucato, E.; Park, H.; Smith, D. R.; Maingi, R.; Sabbagh, S.; Domier, C. W.; Luhmann, N. C. Jr.; Lee, W.

    2008-05-15

    In the National Spherical Torus Experiment [J. Menard et al., Nucl. Fusion 47, S645 (2007)], 'giant' edge localized modes (ELMs) can occur resulting in a loss of plasma stored energy of up to 30%. These events are distinct from type I ELMs, whose energy loss is typically 4-10%, and they are accompanied by a cold pulse that causes a global decrease in the electron temperature profile. Estimates of the electron thermal transport during the cold pulses show a large enhancement over the underlying cross-field thermal diffusivity, {chi}{sub e}, of up to several tens of m{sup 2}/s. Following the ELM, short-wavelength fluctuations increase in the plasma edge and core, corresponding to an increase in the electron temperature gradient from the propagating cold pulse. Fast electron temperature measurements indicate that the normalized electron temperature scale length, R/L{sub Te}, reaches the threshold value for instability predicted by a fit to linear stability calculations. This is observed on time scales that match the growth of the high-k fluctuations in the plasma core, indicating that the enhanced {chi}{sub e} and energy loss from the 'giant' ELM appears to be related to critical gradient physics and the destabilization of electron temperature gradient modes.

  10. Relationship between edge localized mode severity and electron transport in the National Spherical Torus Experiment

    SciTech Connect

    Tritz, K.; Kaye, S.; Maingi, R.; Sabbagh, S. A.; Stutman, D.; Bell, R. E.; Delgado-Aparicio, L.; Domier, C. W.; Finkenthal, M.; LeBlanc, B; Lee, W.; Luhmann, N. C.; Mazzucato, E.; Park, H.; Smith, D. R.

    2008-01-01

    n the National Spherical Torus Experiment [J. Menard , Nucl. Fusion 47, S645 (2007)], "giant" edge localized modes (ELMs) can occur resulting in a loss of plasma stored energy of up to 30%. These events are distinct from type I ELMs, whose energy loss is typically 4-10%, and they are accompanied by a cold pulse that causes a global decrease in the electron temperature profile. Estimates of the electron thermal transport during the cold pulses show a large enhancement over the underlying cross-field thermal diffusivity, chi(e), of up to several tens of m(2)/s. Following the ELM, short-wavelength fluctuations increase in the plasma edge and core, corresponding to an increase in the electron temperature gradient from the propagating cold pulse. Fast electron temperature measurements indicate that the normalized electron temperature scale length, R/L-Te, reaches the threshold value for instability predicted by a fit to linear stability calculations. This is observed on time scales that match the growth of the high-k fluctuations in the plasma core, indicating that the enhanced chi(e) and energy loss from the "giant" ELM appears to be related to critical gradient physics and the destabilization of electron temperature gradient modes. (C) 2008 American Institute of Physics.

  11. Relationship between edge localized mode severity and electron transport in the National Spherical Torus Experimenta)

    NASA Astrophysics Data System (ADS)

    Tritz, K.; Kaye, S.; Maingi, R.; Sabbagh, S.; Stutman, D.; Bell, R.; Delgado-Aparicio, L.; Domier, C. W.; Finkenthal, M.; LeBlanc, B.; Lee, W.; Luhmann, N. C.; Mazzucato, E.; Park, H.; Smith, D. R.

    2008-05-01

    In the National Spherical Torus Experiment [J. Menard et al., Nucl. Fusion 47, S645 (2007)], "giant" edge localized modes (ELMs) can occur resulting in a loss of plasma stored energy of up to 30%. These events are distinct from type I ELMs, whose energy loss is typically 4-10%, and they are accompanied by a cold pulse that causes a global decrease in the electron temperature profile. Estimates of the electron thermal transport during the cold pulses show a large enhancement over the underlying cross-field thermal diffusivity, χe, of up to several tens of m2/s. Following the ELM, short-wavelength fluctuations increase in the plasma edge and core, corresponding to an increase in the electron temperature gradient from the propagating cold pulse. Fast electron temperature measurements indicate that the normalized electron temperature scale length, R /LTe, reaches the threshold value for instability predicted by a fit to linear stability calculations. This is observed on time scales that match the growth of the high-k fluctuations in the plasma core, indicating that the enhanced χe and energy loss from the "giant" ELM appears to be related to critical gradient physics and the destabilization of electron temperature gradient modes.

  12. From global to local: exploring the relationship between parameters and behaviors in models of electrical excitability.

    PubMed

    Fletcher, Patrick; Bertram, Richard; Tabak, Joel

    2016-06-01

    Models of electrical activity in excitable cells involve nonlinear interactions between many ionic currents. Changing parameters in these models can produce a variety of activity patterns with sometimes unexpected effects. Further more, introducing new currents will have different effects depending on the initial parameter set. In this study we combined global sampling of parameter space and local analysis of representative parameter sets in a pituitary cell model to understand the effects of adding K (+) conductances, which mediate some effects of hormone action on these cells. Global sampling ensured that the effects of introducing K (+) conductances were captured across a wide variety of contexts of model parameters. For each type of K (+) conductance we determined the types of behavioral transition that it evoked. Some transitions were counterintuitive, and may have been missed without the use of global sampling. In general, the wide range of transitions that occurred when the same current was applied to the model cell at different locations in parameter space highlight the challenge of making accurate model predictions in light of cell-to-cell heterogeneity. Finally, we used bifurcation analysis and fast/slow analysis to investigate why specific transitions occur in representative individual models. This approach relies on the use of a graphics processing unit (GPU) to quickly map parameter space to model behavior and identify parameter sets for further analysis. Acceleration with modern low-cost GPUs is particularly well suited to exploring the moderate-sized (5-20) parameter spaces of excitable cell and signaling models.

  13. The relationships between edge localized modes suppression, pedestal profiles and lithium wall coatings in NSTX

    SciTech Connect

    Boyle, D. P.; Maingi, R.; Snyder, P. B.; Manickam, J.; Osborne, T.H.; Bell, R. E.; LeBlanc, B. P.

    2011-01-01

    Recently in the National Spherical Torus Experiment (NSTX), increasing lithium wall coatings suppressed edge localized modes (ELMs), gradually but not quite monotonically. This work details profile and stability analysis as ELMs disappeared throughout the lithium scan. While the quantity of lithium deposited between discharges did not uniquely determine the presence of ELMs, profile analysis demonstrated that lithium was correlated with wider density and pressure pedestals with peak gradients farther from the separatrix. Moreover, the ELMy and ELM-free discharges were cleanly separated by their density and pedestal widths and peak gradient locations. Ultimately, ELMs were only suppressed when lithium caused the density pedestal to widen and shift inward. These changes in the density gradient were directly reflected in the pressure gradient and calculated bootstrap current. This supports the theory that ELMs in NSTX are caused by peeling and/or ballooning modes, as kink/peeling modes are stabilized when the edge current and pressure gradient shift away from the separatrix. Edge stability analysis using ELITE corroborated this picture, as reconstructed equilibria from ELM-free discharges were generally farther from their kink/peeling stability boundaries than ELMy discharges. We conclude that density profile control provided by lithium is the key first step to ELM suppression in NSTX.

  14. Specialist English as a foreign language for European public health: evaluation of competencies and needs among Polish and Lithuanian students.

    PubMed

    Sumskas, Linas; Czabanowska, Katarzyna; Bruneviciūte, Raimonda; Kregzdyte, Rima; Krikstaponyte, Zita; Ziomkiewicz, Anna

    2010-01-01

    Foreign languages are becoming an essential prerequisite for a successful carrier among all professions including public health professionals in many countries. The expanding role of English as a mode of communication allows for university graduates to project and to seek their career in English-speaking countries. The present study was carried out in the framework of EU Leonardo da Vinci project "Specialist English as a foreign language for European public health." The study aimed to get a deeper insight how the English language is perceived as a foreign language, by Polish and Lithuanian public health students, what is level of their language competence, which level of English proficiency they expect to use in future. MATERIAL AND METHODS. A total of 246 respondents completed the special questionnaires in autumn semester in 2005. A questionnaire form was developed by the international project team. For evaluation of English competences, the Language Passport (Common European Framework of Reference for Languages of Council of Europe) was applied. RESULTS. Current self-rated proficiency of the English language was at the same level for Lithuanian (3.47+/-1.14) and Polish (3.31+/-0.83) respondents (P>0.05). Majority of respondents (88.6% of Lithuanian and 87.8% of Polish) reported using the English language for their current studies. Respondents reported a significant increase in necessity for higher level of English proficiency in future: mean scores provided by respondents changed from B1 level to B2 level. Respondents gave priority to less formal and practice-based interactive English teaching methods (going abroad, contacts with native speakers) in comparison with theory-oriented methods of learning (self-studying, Internet courses). CONCLUSIONS. Similar levels of English language in all five areas of language skills were established in Polish and Lithuanian university students. Respondents gave more priorities to less formal and practice-based interactive

  15. Increased tree establishment in Lithuanian peat bogs--insights from field and remotely sensed approaches.

    PubMed

    Edvardsson, Johannes; Šimanauskienė, Rasa; Taminskas, Julius; Baužienė, Ieva; Stoffel, Markus

    2015-02-01

    Over the past century an ongoing establishment of Scots pine (Pinus sylvestris L.), sometimes at accelerating rates, is noted at three studied Lithuanian peat bogs, namely Kerėplis, Rėkyva and Aukštumala, all representing different degrees of tree coverage and geographic settings. Present establishment rates seem to depend on tree density on the bog surface and are most significant at sparsely covered sites where about three-fourth of the trees have established since the mid-1990s, whereas the initial establishment in general was during the early to mid-19th century. Three methods were used to detect, compare and describe tree establishment: (1) tree counts in small plots, (2) dendrochronological dating of bog pine trees, and (3) interpretation of aerial photographs and historical maps of the study areas. In combination, the different approaches provide complimentary information but also weigh up each other's drawbacks. Tree counts in plots provided a reasonable overview of age class distributions and enabled capturing of the most recently established trees with ages less than 50 years. The dendrochronological analysis yielded accurate tree ages and a good temporal resolution of long-term changes. Tree establishment and spread interpreted from aerial photographs and historical maps provided a good overview of tree spread and total affected area. It also helped to verify the results obtained with the other methods and an upscaling of findings to the entire peat bogs. The ongoing spread of trees in predominantly undisturbed peat bogs is related to warmer and/or drier climatic conditions, and to a minor degree to land-use changes. Our results therefore provide valuable insights into vegetation changes in peat bogs, also with respect to bog response to ongoing and future climatic changes.

  16. Relationship between severity of the local skin reactions and the rate of local skin reaction resolution in patients treated with ingenol mebutate gel

    PubMed Central

    Jim On, Shelbi C; Knudsen, Kim Mark; Skov, Torsten; Lebwohl, Mark

    2016-01-01

    Background Ingenol mebutate gel is a topical field treatment for actinic keratosis (AK). The treatment elicits application-site reactions in most patients. This analysis evaluated the relationship between the severity of reactions and the speed of their resolution. Methods Patients in Phase III studies were treated for AKs on the face (n=218), scalp (n=56), and trunk and extremities (n=209). All of the patients were treated with either ingenol mebutate gel 0.015% once daily for three consecutive days (face/scalp) or ingenol mebutate gel 0.05% once daily for two consecutive days (trunk/extremities). Local skin reactions (LSRs) were assessed on a 5-point scale from 0 to 4 in six categories, yielding composite scores in the range of 0 to 24. Results The composite LSR score on the day after the last application of ingenol mebutate gel was an important predictor of the speed of resolution of LSRs. The rate of resolution was greatest for AKs treated on the face, followed by the scalp, and then the trunk and extremities. All patients were expected to have minimal LSR scores for the face and scalp at 2 weeks, and for the trunk and extremities at 4 weeks. Conclusion The absolute reduction in LSR scores was proportional to the composite LSR score on the day after the last application of ingenol mebutate gel treatment. The rate of resolution for LSRs was dependent on the anatomic site treated as well as the day 4 composite score. PMID:27601928

  17. Effect of excess body weight on quality of life and satisfaction with body image among middle-aged Lithuanian inhabitants of Kaunas city.

    PubMed

    Baceviciene, Migle; Reklaitiene, Regina; Tamosiūnas, Abdonas

    2009-01-01

    The aim of the study was to identify the effect of overweight, obesity, and conditions related to body weight on quality of life and to assess the relationship between body weight and satisfaction with body image between middle-aged Lithuanian inhabitants of Kaunas city. MATERIAL AND METHODS. A random sample of 1403 Kaunas men and women, aged 35-64 years and stratified by age and sex, was examined in 2001-2002. Response rate was 62.4%. Examination included physical measurements and information on risk factors related to lifestyle. Quality of life was assessed by World Health Organization Quality of Life 100 questionnaire. Multivariate analyses were performed to identify the effect of excess body weight and conditions linked to body weight on quality of life. RESULTS. Less than three-fourths (73%) of men and women had excess body weight (body mass index, > or =25.0 kg/m(2)). Obesity in a complex with other analyzed factors had a negative effect on men's quality of life in the independence domain as compared to ones with BMI of <25.0 kg/m(2) (OR=1.87; 95% CI=1.08-3.26). Obesity for women increased the odds of having worse quality of life in the psychological and independence domains. Mean scores of body image and appearance facet for men with normal body mass were 73.5, for overweigh ones 72.2, and for obese 66.8 (for women 69.9, 63.3, and 52.9, respectively; P=0.0001). CONCLUSIONS. Among women excess body weight was associated with impaired quality of life. Men with excess body weight reported better overall quality of life. Obese persons were less satisfied with their body image as compared to ones with normal body weight.

  18. Barriers to cancer pain management in Danish and Lithuanian patients treated in pain and palliative care units.

    PubMed

    Jacobsen, Ramune; Samsanaviciene, Jurgita; Liubarskiene, Zita; Sjøgren, Per; Møldrup, Claus; Christrup, Lona; Sciupokas, Arunas; Hansen, Ole Bo

    2014-03-01

    The prevalence of cancer-related pain is high despite available guidelines for the effective assessment and management of that pain. Barriers to the use of opioid analgesics partially cause undertreatment of cancer pain. The aim of this study was to compare pain management outcomes and patient-related barriers to cancer pain management in patient samples from Denmark and Lithuania. Thirty-three Danish and 30 Lithuanian patients responded to, respectively, Danish and Lithuanian versions of the Brief Pain Inventory pain scale, the Barriers Questionnaire II, the Hospital Anxiety and Depression Scale, the Specific Questionnaire On Pain Communication, and the Medication Adherence Report Scale. Emotional distress and patient attitudes toward opioid analgesics in cancer patient samples from both countries explained pain management outcomes in the multivariate regression models. Pain relief and pain medication adherence were better in Denmark, and the country of origin significantly explained the difference in the regression models for these outcomes. In conclusion, interventions in emotional distress and patient attitudes toward opioid analgesics may result in better pain management outcomes generally, whereas poor adherence to pain medication and poor pain relief appear to be more country-specific problems.

  19. PISA Test Items and School-Based Examinations in Greece: Exploring the relationship between global and local assessment discourses

    NASA Astrophysics Data System (ADS)

    Anagnostopoulou, Kyriaki; Hatzinikita, Vassilia; Christidou, Vasilia; Dimopoulos, Kostas

    2013-03-01

    The paper explores the relationship of the global and the local assessment discourses as expressed by Programme for International Student Assessment (PISA) test items and school-based examinations, respectively. To this end, the paper compares PISA test items related to living systems and the context of life, health, and environment, with Greek school-based biology examinations' test items in terms of the nature of their textual construction. This nature is determined by the interplay of the notions of classification (content specialisation) and formality (code specialisation) modulated by both the linguistic and the visual expressive modes. The results of the analysis reveal disparities between assessment discourses promoted at the global and the local level. In particular, while PISA test items convey their scientific message (specialised content and code) principally through their visual mode, the specialised scientific meaning of school-based examinations test is mainly conveyed through their linguistic mode. On the other hand, the linguistic mode of PISA test items is mainly compatible with textual practices of the public domain (non-specialised content and code). Such a mismatch between assessment discourses at local and global level is expected to place Greek students at different discursive positions, promoting different types of knowledge. The expected shift from the epistemic positioning promoted in Greece to the one promoted by PISA could significantly restrict Greek students' ability to infer the PISA discursive context and produce appropriate responses. This factor could provide a meaningful contribution in the discussion of the relatively low achievement of Greek students in PISA scientific literacy assessment.

  20. The Prevalence of Cyberbullying and the Views of 5-12 Grade Pupils and Teachers on Cyberbullying Prevention in Lithuanian Schools

    ERIC Educational Resources Information Center

    Baraldsnes, Dziuginta

    2015-01-01

    This article analyses the views of cyberbullying prevention among 5-12 grade pupils and teachers in Lithuanian schools. It defines the concept of cyberbullying in the context of school pupils, and analyses the theoretical grounds for prevention of this form of bullying. The article also presents the results of the survey (which was conducted in…

  1. Trends of smoking prevalence among Lithuanian school-aged children in 1994-2006.

    PubMed

    Zaborskis, Apolinaras; Sumskas, Linas; Zemaitiene, Nida; Grabauskas, Vilius; Veryga, Aurelijus; Petkevicius, Robertas

    2009-01-01

    BACKGROUND. Despite much effort spent on antismoking programs in schools in different countries, limited effects have been observed in many cases. Evidence from European countries shows that active tobacco control actions such as ban on tobacco advertising, increase of tobacco taxes could lead to successful results. Our study was aimed to analyze time trends on smoking in Lithuanian school-aged children during the period of 1994-2006 in the context of antismoking policies, which were implemented in Lithuania. MATERIAL AND METHODS. This study was a part of WHO Cross-National Health Behavior in School-Aged Children (HBSC) study carried out in Lithuania. The standardized methods of international HBSC study protocol were applied. Stratified random representative samples of 5428, 4513, 5645, and 5632 students aged 11, 13, and 15 years were included into school-based anonymous questionnaire surveys in 1994, 1998, 2002, and 2006, respectively (spring semester). Questions on frequency of smoking, age of initiation and other questions were included. Response rates of each of these four questionnaire surveys were higher than 90%. RESULTS. Smoking behavior was more common among boys. The prevalence gap in smoking between boys and girls diminished during period of observation. Prevalence of smoking increased significantly among boys during the period of 1994-2002 (11.3%, 19.8%, and 23.6% in 1994, 1998, and 2002, respectively), but started to decline after (17.3% in 2006, P<0.05). Similar trends were observed among girls: 3.6%, 8.5%, 14.6%, and 12.5% of girls reported smoking in cross-sectional surveys of 1994, 1998, 2002, and 2006, respectively. Boys living in rural areas were more frequent smokers than those living in urban areas in 1994-1998 (9.5% vs 13.9%, P<0.05). However, the surveys of 2002-2006 showed opposite changes (25.6% vs 22.1%, P<0.05 and 17.8% vs 16.9%, P>0.05). Urban girls have reported smoking more frequently in comparison with rural girls. CONCLUSIONS. An

  2. The Impact of Event Scale – Revised: psychometric properties of the Lithuanian version in a sample of employees exposed to workplace bullying

    PubMed Central

    Vilija, Malinauskienė; Lina, Bernotaitė

    2016-01-01

    Background. The Impact of Event Scale-Revised (IES-R) is often used as a self-report instrument for symptoms of post-traumatic stress (PTS). The objective of this study was to explore the reliability and validity of the Lithuanian IES-R in a sample of employees with exposure to workplace bullying in different occupations. Materials and methods. The original IES-R was translated into Lithuanian, and the comparability of content was verified through back-translation procedures. 294 employees with exposure to workplace bullying (52 teachers from the secondary schools of Kaunas, 56 family physicians, 101 nurses of internal medicine departments, 40 waiters, and 45 seafarers) were administered the Lithuanian IES-R and the General Health Questionnaire – 12 (GHQ-12) in order to verify some aspects of convergent validity. The exploratory factor analysis was used to verify the construct validity of the IES-R. Results. The reliability of the Lithuanian version of the IES-R was verified. Cronbach’s α of the total scale was 0.95. Exploratory factor analysis showed a clear factor structure with three independent dimensions: intrusion, avoidance and hyperarousal. Cronbach’s α for subscales of intrusion, avoidance and hyperarousal were 0.89, 0.85, and 0.88, respectively. The convergent validity was supported by positive correlations between the subscales (intrusion, avoidance, hyperarousal) and the GHQ-12. Conclusions. The results suggest that the self-reported Lithuanian IES-R is a valid instrument for assessing the dimensions of post-traumatic stress, has good psychometric properties, and may be applied in prolonged trauma-exposed populations. PMID:28356808

  3. Mercury levels assessment and its relationship with oxidative stress biomarkers in children from three localities in Yucatan, Mexico.

    PubMed

    Rangel-Méndez, Jorge A; Arcega-Cabrera, Flor E; Fargher, Lane F; Moo-Puc, Rosa E

    2016-02-01

    Mercury (Hg) is a global pollutant that is released into the environment from geologic and anthropogenic sources. Once it enters an organism, it generates several toxicity mechanisms and oxidative stress has been proposed as the main one. Metal susceptibility is greater in children, which is a result of their physiology and behavior. In Yucatan, Mexico, burning of unregulated garbage dumps and household trash, ingestion of top marine predators, and pottery manufacturing are among the conditions that could promote Hg exposure. However, for Yucatan, there are no published studies that report Hg levels and associated oxidative stress status in children. Therefore, this study aimed to assess Hg levels in blood and urine and oxidative stress biomarkers levels in a sample of 107 healthy children from three localities in Yucatan, Mexico, as well as investigate the relationship between these parameters. Hg was detected in 11 (10.28%) of blood samples and 38 (35.51%) of urine samples collected from the participating children. Fourteen subjects showed Hg above recommended levels. The oxidative stress biomarkers were slightly elevated in comparison with other studies and were statistically different between the sampling sites. No linear correlation between Hg levels and oxidative stress biomarkers was found. Nevertheless, exploratory univariate and multivariate analysis showed non-linear relations among the measured variables. Globally, the study provides, for the first time, information regarding Hg levels and their relationship with oxidative stress biomarkers in a juvenile population from Mexico's southeast (Yucatan) region. In agreement with worldwide concern about Hg, this study should stimulate studies on metal monitoring in humans (especially children) among scientists working in Mexico, the establishment of polices for its regulation, and the reduction of human health risks.

  4. Do clouds save the great barrier reef? satellite imagery elucidates the cloud-SST relationship at the local scale.

    PubMed

    Leahy, Susannah M; Kingsford, Michael J; Steinberg, Craig R

    2013-01-01

    Evidence of global climate change and rising sea surface temperatures (SSTs) is now well documented in the scientific literature. With corals already living close to their thermal maxima, increases in SSTs are of great concern for the survival of coral reefs. Cloud feedback processes may have the potential to constrain SSTs, serving to enforce an "ocean thermostat" and promoting the survival of coral reefs. In this study, it was hypothesized that cloud cover can affect summer SSTs in the tropics. Detailed direct and lagged relationships between cloud cover and SST across the central Great Barrier Reef (GBR) shelf were investigated using data from satellite imagery and in situ temperature and light loggers during two relatively hot summers (2005 and 2006) and two relatively cool summers (2007 and 2008). Across all study summers and shelf positions, SSTs exhibited distinct drops during periods of high cloud cover, and conversely, SST increases during periods of low cloud cover, with a three-day temporal lag between a change in cloud cover and a subsequent change in SST. Cloud cover alone was responsible for up to 32.1% of the variation in SSTs three days later. The relationship was strongest in both El Niño (2005) and La Niña (2008) study summers and at the inner-shelf position in those summers. SST effects on subsequent cloud cover were weaker and more variable among study summers, with rising SSTs explaining up to 21.6% of the increase in cloud cover three days later. This work quantifies the often observed cloud cooling effect on coral reefs. It highlights the importance of incorporating local-scale processes into bleaching forecasting models, and encourages the use of remote sensing imagery to value-add to coral bleaching field studies and to more accurately predict risks to coral reefs.

  5. Do Clouds Save the Great Barrier Reef? Satellite Imagery Elucidates the Cloud-SST Relationship at the Local Scale

    PubMed Central

    Leahy, Susannah M.; Kingsford, Michael J.; Steinberg, Craig R.

    2013-01-01

    Evidence of global climate change and rising sea surface temperatures (SSTs) is now well documented in the scientific literature. With corals already living close to their thermal maxima, increases in SSTs are of great concern for the survival of coral reefs. Cloud feedback processes may have the potential to constrain SSTs, serving to enforce an “ocean thermostat” and promoting the survival of coral reefs. In this study, it was hypothesized that cloud cover can affect summer SSTs in the tropics. Detailed direct and lagged relationships between cloud cover and SST across the central Great Barrier Reef (GBR) shelf were investigated using data from satellite imagery and in situ temperature and light loggers during two relatively hot summers (2005 and 2006) and two relatively cool summers (2007 and 2008). Across all study summers and shelf positions, SSTs exhibited distinct drops during periods of high cloud cover, and conversely, SST increases during periods of low cloud cover, with a three-day temporal lag between a change in cloud cover and a subsequent change in SST. Cloud cover alone was responsible for up to 32.1% of the variation in SSTs three days later. The relationship was strongest in both El Niño (2005) and La Niña (2008) study summers and at the inner-shelf position in those summers. SST effects on subsequent cloud cover were weaker and more variable among study summers, with rising SSTs explaining up to 21.6% of the increase in cloud cover three days later. This work quantifies the often observed cloud cooling effect on coral reefs. It highlights the importance of incorporating local-scale processes into bleaching forecasting models, and encourages the use of remote sensing imagery to value-add to coral bleaching field studies and to more accurately predict risks to coral reefs. PMID:23894649

  6. Local Context Finder (LCF) reveals multidimensional relationships among mRNA expression profiles of Arabidopsis responding to pathogen infection.

    PubMed

    Katagiri, Fumiaki; Glazebrook, Jane

    2003-09-16

    A major task in computational analysis of mRNA expression profiles is definition of relationships among profiles on the basis of similarities among them. This is generally achieved by pattern recognition in the distribution of data points representing each profile in a high-dimensional space. Some drawbacks of commonly used pattern recognition algorithms stem from their use of a globally linear space and/or limited degrees of freedom. A pattern recognition method called Local Context Finder (LCF) is described here. LCF uses nonlinear dimensionality reduction for pattern recognition. Then it builds a network of profiles based on the nonlinear dimensionality reduction results. LCF was used to analyze mRNA expression profiles of the plant host Arabidopsis interacting with the bacterial pathogen Pseudomonas syringae. In one case, LCF revealed two dimensions essential to explain the effects of the NahG transgene and the ndr1 mutation on resistant and susceptible responses. In another case, plant mutants deficient in responses to pathogen infection were classified on the basis of LCF analysis of their profiles. The classification by LCF was consistent with the results of biological characterization of the mutants. Thus, LCF is a powerful method for extracting information from expression profile data.

  7. AMPD1 rs17602729 is associated with physical performance of sprint and power in elite Lithuanian athletes

    PubMed Central

    2014-01-01

    Background The C34T genetic polymorphism (rs17602729) in the AMPD1 gene, encoding the skeletal muscle-specific isoform of adenosine monophosphate deaminase (AMPD1), is a common polymorphism among Caucasians that can impair exercise capacity. The aim of the present study was twofold: (1) to determine the C34T AMPD1 allele/genotype frequency distributions in Lithuanian athletes (n = 204, stratified into three groups: endurance, sprint/power and mixed) and compare them with the allele/genotype frequency distributions in randomly selected healthy Lithuanian non-athletes (n = 260) and (2) to compare common anthropometric measurements and physical performance phenotypes between the three groups of athletes depending on their AMPD1 genotype. Results The results of our study indicate that the frequency of the AMPD1 TT genotype was 2.4% in the control group, while it was absent in the athlete group. There were significantly more sprint/power-orientated athletes with the CC genotype (86.3%) compared with the endurance-orientated athletes (72.9%), mixed athletes (67.1%), and controls (74.2%). We determined that the AMPD1 C34T polymorphism is not associated with aerobic muscle performance phenotype (VO2max). For CC genotype the short-term explosive muscle power value (based on Vertical Jump test) of athletes from the sprint/power group was significantly higher than that of the endurance group athletes (P < 0.05). The AMPD1 CC genotype is associated with anaerobic performance (Vertical Jump). Conclusions The AMPD1 C allele may help athletes to attain elite status in sprint/power-oriented sports, and the T allele is a factor unfavourable for athletics in sprint/power-oriented sports categories. Hence, the AMPD1 C allele can be regarded as a marker associated with the physical performance of sprint and power. Replications studies are required to confirm this association. PMID:24885427

  8. Dose-Effect Relationship in Chemoradiotherapy for Locally Advanced Rectal Cancer: A Randomized Trial Comparing Two Radiation Doses

    SciTech Connect

    Jakobsen, Anders; Ploen, John; Vuong, Te; Appelt, Ane; Lindebjerg, Jan; Rafaelsen, Soren R.

    2012-11-15

    Purpose: Locally advanced rectal cancer represents a major therapeutic challenge. Preoperative chemoradiation therapy is considered standard, but little is known about the dose-effect relationship. The present study represents a dose-escalation phase III trial comparing 2 doses of radiation. Methods and Materials: The inclusion criteria were resectable T3 and T4 tumors with a circumferential margin of {<=}5 mm on magnetic resonance imaging. The patients were randomized to receive 50.4 Gy in 28 fractions to the tumor and pelvic lymph nodes (arm A) or the same treatment supplemented with an endorectal boost given as high-dose-rate brachytherapy (10 Gy in 2 fractions; arm B). Concomitant chemotherapy, uftoral 300 mg/m{sup 2} and L-leucovorin 22.5 mg/d, was added to both arms on treatment days. The primary endpoint was complete pathologic remission. The secondary endpoints included tumor response and rate of complete resection (R0). Results: The study included 248 patients. No significant difference was found in toxicity or surgical complications between the 2 groups. Based on intention to treat, no significant difference was found in the complete pathologic remission rate between the 2 arms (18% and 18%). The rate of R0 resection was different in T3 tumors (90% and 99%; P=.03). The same applied to the rate of major response (tumor regression grade, 1+2), 29% and 44%, respectively (P=.04). Conclusions: This first randomized trial comparing 2 radiation doses indicated that the higher dose increased the rate of major response by 50% in T3 tumors. The endorectal boost is feasible, with no significant increase in toxicity or surgical complications.

  9. PSMA6 (rs2277460, rs1048990), PSMC6 (rs2295826, rs2295827) and PSMA3 (rs2348071) genetic diversity in Latvians, Lithuanians and Taiwanese

    PubMed Central

    Sjakste, Tatjana; Paramonova, Natalia; Wu, Lawrence Shi-Shin; Zemeckiene, Zivile; Sitkauskiene, Brigita; Sakalauskas, Raimundas; Wang, Jiu-Yao; Sjakste, Nikolajs

    2014-01-01

    PSMA6 (rs2277460, rs1048990), PSMC6 (rs2295826, rs2295827) and PSMA3 (rs2348071) genetic diversity was investigated in 1438 unrelated subjects from Latvia, Lithuania and Taiwan. In general, polymorphism of each individual locus showed tendencies similar to determined previously in HapMap populations. Main differences concern Taiwanese and include presence of rs2277460 rare allele A not found before in Asians and absence of rs2295827 rare alleles homozygotes TT observed in all other human populations. Observed patterns of SNPs and haplotype diversity were compatible with expectation of neutral model of evolution. Linkage disequilibrium between the rs2295826 and rs2295827 was detected to be complete in Latvians and Lithuanians (D´ = 1; r2 = 1) and slightly disrupted in Taiwanese (D´ = 0.978; r2 = 0.901). Population differentiation (FST statistics) was estimated from pairwise population comparisons of loci variability, five locus haplotypes and PSMA6 and PSMC6 two locus haplotypes. Latvians were significantly different from all Asians at each of 5 SNPs and from Lithuanians at the rs1048990 and PSMC6 loci. Lithuanian and Asian populations exhibited similarities at the PSMC6 loci and were different at the PSMA6 and PSMA3 SNPs. Considering five locus haplotypes all European populations were significantly different from Asian; Lithuanian population was different from both Latvian and CEU. Allele specific patterns of transcription factor binding sites and splicing signals were predicted in silico and addressed to eventual functionality of nucleotide substitutions and their potential to be involved in human genome evolution and geographical adaptation. Current study represents a novel step toward a systematic analysis of the proteasomal gene genetic diversity in human populations. PMID:25606411

  10. Relationship between Broken Homes and Academic Achievement of Secondary School Students in Oredo Local Government Area of Edo State, Nigeria

    ERIC Educational Resources Information Center

    Alika, Henrietta Ijeoma; Edosa, Ogboro Samson

    2012-01-01

    The study investigated the relationship between broken homes and academic achievement of students. Three research hypotheses were formulated to guide the study. The study was correlational because the study sought to establish the extent of relationship between broken homes and academic achievement. The statistical method used in analyzing the…

  11. Significant Local-Scale Plant-Insect Species Richness Relationship Independent of Abiotic Effects in the Temperate Cape Floristic Region Biodiversity Hotspot.

    PubMed

    Kemp, Jurene E; Ellis, Allan G

    2017-01-01

    Globally plant species richness is a significant predictor of insect richness. Whether this is the result of insect diversity responding directly to plant diversity, or both groups responding in similar ways to extrinsic factors, has been much debated. Here we assess this relationship in the Cape Floristic Region (CFR), a biodiversity hotspot. The CFR has higher plant diversity than expected from latitude (i.e., abiotic conditions), but very little is known about the diversity of insects residing in this region. We first quantify diversity relationships at multiple spatial scales for one of the dominant plant families in the CFR, the Restionaceae, and its associated insect herbivore community. Plant and insect diversity are significantly positively correlated at the local scales (10-50 m; 0.1-3 km), but not at the regional scales (15-20 km; 50-70 km). The local scale relationship remains significantly positively correlated even when accounting for the influence of extrinsic variables and other vegetation attributes. This suggests that the diversity of local insect assemblages may be more strongly influenced by plant species richness than by abiotic variables. Further, vegetation age and plant structural complexity also influenced insect richness. The ratio of insect species per plant species in the CFR is comparable to other temperate regions around the world, suggesting that the insect diversity of the CFR is high relative to other areas of the globe with similar abiotic conditions, primarily as a result of the unusually high plant diversity in the region.

  12. Significant Local-Scale Plant-Insect Species Richness Relationship Independent of Abiotic Effects in the Temperate Cape Floristic Region Biodiversity Hotspot

    PubMed Central

    Kemp, Jurene E.; Ellis, Allan G.

    2017-01-01

    Globally plant species richness is a significant predictor of insect richness. Whether this is the result of insect diversity responding directly to plant diversity, or both groups responding in similar ways to extrinsic factors, has been much debated. Here we assess this relationship in the Cape Floristic Region (CFR), a biodiversity hotspot. The CFR has higher plant diversity than expected from latitude (i.e., abiotic conditions), but very little is known about the diversity of insects residing in this region. We first quantify diversity relationships at multiple spatial scales for one of the dominant plant families in the CFR, the Restionaceae, and its associated insect herbivore community. Plant and insect diversity are significantly positively correlated at the local scales (10–50 m; 0.1–3 km), but not at the regional scales (15–20 km; 50–70 km). The local scale relationship remains significantly positively correlated even when accounting for the influence of extrinsic variables and other vegetation attributes. This suggests that the diversity of local insect assemblages may be more strongly influenced by plant species richness than by abiotic variables. Further, vegetation age and plant structural complexity also influenced insect richness. The ratio of insect species per plant species in the CFR is comparable to other temperate regions around the world, suggesting that the insect diversity of the CFR is high relative to other areas of the globe with similar abiotic conditions, primarily as a result of the unusually high plant diversity in the region. PMID:28076412

  13. Sexual behavior and high-risk human papillomavirus in 15- to 22-year-old Lithuanian women.

    PubMed

    Bumbuliene, Zana; Alisauskas, Jonas

    2012-04-01

    We determined the risk of high-risk human papillomavirus (HR-HPV) infection in 169 15- to 22-year-old sexually active Lithuanian women attending two outpatient clinics in Vilnius. The Digene(®) Hybrid Capture II DNA test was used to test for HR-HPV infection on material collected by cervical swabs. The findings were compared with the pattern of sexual behavior as given in questionnaire replies. The overall risk of HR-HPV was 23.1%, but 60.0% in adolescents ≤15 years old. Mean age at first intercourse was 17.1 years; 73.5% of women had only had one sexual partner and 24.5% more than one. The risk of HR-HPV was higher in women with more than one sexual partner, and related to being a smoker and to early age at the first intercourse. Our results confirm that smoking, early coitarche, multiple sexual partners and unprotected vaginal intercourse are related to the risk of HR-HPV infection in young women.

  14. Increasing attendance in a cervical cancer screening programme by personal invitation: experience of a Lithuanian primary health care centre

    PubMed Central

    Rūta, Kurtinaitienė; Jolita, Rimienė; Ingrida, Labanauskaitė; Nadežda, Lipunova; Giedrė, Smailytė

    2016-01-01

    Background. High participation rates are an essential component of an effective screening programme and many approaches were introduced as being successful for enhancing compliance to screening guidelines. The aim of this study was to evaluate to which extent a personal invitation by mail increases the rate of attendance in a cervical cancer screening programme in a primary health care centre. Materials and methods. The study was carried out as a pilot project to gain insight into feasibility of applying a well-known compliance increasing measure in Lithuanian population. The study included a sample of women registered at the primary health care centre in Panevėžys who had not participated in the cervical cancer screening programme for six and more years. Personal registered invitation letters to attend the primary health care centre for a Pap smear were sent out to 1789 women by mail. Results. In total, 2195 women were tested during 2011 at the primary health care centre. 487 (22.2%) of them attended the screening programme after receiving a personal invitation letter. Response rate for attending screening after receiving a personal invitation letter was 27.3%. Conclusions. Our study demonstrated that personal invitation letters addressed to long-term non-attendees could markedly increase participation in cervical cancer screening in Lithuania. PMID:28356807

  15. A Study of the Relationship Between Selected Socioeconomic Variables and Local Tax Effort to Support Public Schools in Illinois.

    ERIC Educational Resources Information Center

    Yang, Thomas Wei-Chi; Chaudhari, Ramesh

    This study examined the relationship between operating tax rates and selected socioeconomic variables for Illinois school districts. Districts were separately ranked by operating tax rates and then divided into four equal quartiles--low tax effort, low medium tax effort, high medium tax effort, and high tax effort. Discriminant analysis was used…

  16. The Intuitive Style: Relationships with Local/Global and Verbal/Visual Styles, Gender, and Superstitious Reasoning

    ERIC Educational Resources Information Center

    Sadler-Smith, Eugene

    2011-01-01

    The study explored various facets of the intuitive style and its relevance to learning and education from a dual-processing perspective, namely how it relates to other style constructs (analytical; visual and verbal; local and global), gender, and superstitious reasoning and how these are likely to impact upon learning in educational and…

  17. 20 CFR 661.335 - What is a youth council, and what is its relationship to the Local Board?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of human service agencies, who have special interest or expertise in youth policy; (2) Members who... organizations, that have experience relating to youth activities; and (6) Members who represent the Job Corps, if a Job Corps Center is located in the local area represented by the council. (c) Youth councils...

  18. 20 CFR 661.335 - What is a youth council, and what is its relationship to the Local Board?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... representatives of human service agencies, who have special interest or expertise in youth policy; (2) Members who... organizations, that have experience relating to youth activities; and (6) Members who represent the Job Corps, if a Job Corps Center is located in the local area represented by the council. (c) Youth councils...

  19. 20 CFR 661.335 - What is a youth council, and what is its relationship to the Local Board?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... representatives of human service agencies, who have special interest or expertise in youth policy; (2) Members who... organizations, that have experience relating to youth activities; and (6) Members who represent the Job Corps, if a Job Corps Center is located in the local area represented by the council. (c) Youth councils...

  20. Alzheimer's Disease Can Spare Local Metacognition Despite Global Anosognosia: Revisiting the Confidence-Accuracy Relationship in Episodic Memory

    ERIC Educational Resources Information Center

    Gallo, David A.; Cramer, Stefanie J.; Wong, Jessica T.; Bennett, David A.

    2012-01-01

    Alzheimer's disease (AD) can impair metacognition in addition to more basic cognitive functions like memory. However, while global metacognitive inaccuracies are well documented (i.e., low deficit awareness, or anosognosia), the evidence is mixed regarding the effects of AD on local or task-based metacognitive judgments. Here we investigated local…

  1. Being Close: The Quality of Social Relationships in a Local Organic Cereal and Bread Network in Lower Austria

    ERIC Educational Resources Information Center

    Milestad, Rebecka; Bartel-Kratochvil, Ruth; Leitner, Heidrun; Axmann, Paul

    2010-01-01

    Experience of the drawbacks of a globalised and industrialised food system has generated interest in localised food systems. Local food networks are regarded as more sustainable food provision systems since they are assumed to have high levels of social embeddedness and relations of regard. This paper explores the social relations between food…

  2. Establishing Authentic Lithuanian Culture and Values in Post-Soviet Educational Policy and Practice

    ERIC Educational Resources Information Center

    Williams, Stephen E.; Gray, Philip

    2004-01-01

    This article considers the role of culture in establishing a program of educational reform in Lithuania, a former Soviet Bloc state. Specifically, through a comparative analysis of survey information from an international cross-section of individuals involved with educational reform programs in Lithuania at the local, regional, and national…

  3. Relationship of Clinical and Pathologic Nodal Staging in Locally Advanced Breast Cancer: Current Controversies in Daily Practice?

    PubMed Central

    De Felice, Francesca; Musio, Daniela; Bulzonetti, Nadia; Raffetto, Nicola; Tombolini, Vincenzo

    2014-01-01

    Systemic neo-adjuvant therapy plays a primary role in the management of locally advanced breast cancer. Without having any negative effect in overall survival, induction chemotherapy potentially assures a surgery approach in unresectable disease or a conservative treatment in technically resectable disease and acts on a well-vascularized tumor bed, without the modifications induced by surgery. A specific issue has a central function in the neo-adjuvant setting: lymph nodes status. It still represents one of the strongest predictors of long-term prognosis in breast cancer. The discussion of regional radiation therapy should be a matter of debate, especially in a pathological complete response. Currently, the indication for radiotherapy is based on the clinical stage before the surgery, even for the irradiation of the loco-regional lymph nodes. Regardless of pathological down-staging, radiation therapy is accepted as standard adjuvant treatment in locally advanced breast cancer. PMID:25247013

  4. A novel method for discovering local spatial clusters of genomic regions with functional relationships from DNA contact maps

    PubMed Central

    Hu, Xihao; Shi, Christina Huan; Yip, Kevin Y.

    2016-01-01

    Motivation: The three-dimensional structure of genomes makes it possible for genomic regions not adjacent in the primary sequence to be spatially proximal. These DNA contacts have been found to be related to various molecular activities. Previous methods for analyzing DNA contact maps obtained from Hi-C experiments have largely focused on studying individual interactions, forming spatial clusters composed of contiguous blocks of genomic locations, or classifying these clusters into general categories based on some global properties of the contact maps. Results: Here, we describe a novel computational method that can flexibly identify small clusters of spatially proximal genomic regions based on their local contact patterns. Using simulated data that highly resemble Hi-C data obtained from real genome structures, we demonstrate that our method identifies spatial clusters that are more compact than methods previously used for clustering genomic regions based on DNA contact maps. The clusters identified by our method enable us to confirm functionally related genomic regions previously reported to be spatially proximal in different species. We further show that each genomic region can be assigned a numeric affinity value that indicates its degree of participation in each local cluster, and these affinity values correlate quantitatively with DNase I hypersensitivity, gene expression, super enhancer activities and replication timing in a cell type specific manner. We also show that these cluster affinity values can precisely define boundaries of reported topologically associating domains, and further define local sub-domains within each domain. Availability and implementation: The source code of BNMF and tutorials on how to use the software to extract local clusters from contact maps are available at http://yiplab.cse.cuhk.edu.hk/bnmf/. Contact: kevinyip@cse.cuhk.edu.hk Supplementary information: Supplementary data are available at Bioinformatics online. PMID:27307607

  5. Localization studies of rare missense mutations in cystic fibrosis transmembrane conductance regulator (CFTR) facilitate interpretation of genotype-phenotype relationships.

    PubMed

    Krasnov, Kristina V; Tzetis, Maria; Cheng, Jie; Guggino, William B; Cutting, Garry R

    2008-11-01

    We have been investigating the functional consequences of rare disease-associated amino acid substitutions in the cystic fibrosis transmembrane conductance regulator (CFTR). Mutations of the arginine residue at codon 1070 have been associated with different disease consequences; R1070P and R1070Q with "severe" pancreatic insufficient cystic fibrosis (CF) and R1070W with "mild" pancreatic sufficient CF or congenital bilateral absence of the vas deferens. Intriguingly, CFTR bearing each of these mutations is functional when expressed in nonpolarized cells. To determine whether R1070 mutations cause disease by affecting CFTR localization, we created polarized Madin Darby canine kidney (MDCK) cell lines that express either wild-type or mutant CFTR from the same genomic integration site. Confocal microscopy and biotinylation studies revealed that R1070P was not inserted into the apical membrane, R1070W was inserted at levels reduced from wild-type while R1070Q was present in the apical membrane at levels comparable to wild-type. The abnormal localization of CFTR bearing R1070P and R1070W was consistent with deleterious consequences in patients; however, the profile of CFTR R1070Q was inconsistent with a "severe" phenotype. Reanalysis of 16 patients with the R1070Q mutation revealed that 11 carried an in cis nonsense mutation, S466X. All 11 patients carrying the complex allele R1070Q-S466X had severe disease, while 4 out of 5 patients with R1070Q had "mild" disease, thereby reconciling the apparent discrepancy between the localization studies of R1070Q and the phenotype of patients bearing this mutation. Our results emphasize that localization studies in relevant model systems can greatly assist the interpretation of the disease-causing potential of rare missense mutations.

  6. Prevalence and extent of dental caries, dental fluorosis, and developmental enamel defects in Lithuanian teenage populations with different fluoride exposures.

    PubMed

    Machiulskiene, Vita; Baelum, Vibeke; Fejerskov, Ole; Nyvad, Bente

    2009-04-01

    The aim of this study was to describe the pattern of dental caries, dental fluorosis, and developmental defects of non-fluoride origin in Lithuanian children born and raised in regions with 1.1 ppm (1.1 mg/l F) and 0.3 ppm (0.3 mg/l F) water fluoride levels, respectively. All permanent surfaces/teeth of 300 teenagers were examined for dental caries, dental fluorosis, and non-fluoride developmental defects. The caries prevalence of the study population was 100%. The mean number of decayed surfaces (DS) differed only slightly and statistically insignificantly between the '1.1 ppm fluoride' and '0.3 ppm fluoride' groups (19.6 and 18.1, respectively). However, a greater number of inactive lesions and fewer fillings were found in the '1.1 ppm fluoride' group than in the '0.3 ppm fluoride' group (mean difference 1.18 and -2.80, respectively). The prevalence of dental fluorosis was 45% and 21%, respectively; the prevalence of non-fluoride opacities was 8% and 19%, respectively; and the prevalence of hypoplasia was 12% and 16%, respectively, in the '1.1 ppm fluoride' and '0.3 ppm fluoride' groups. Higher caries levels were noted in children with no fluorosis compared to those with fluorosis recorded (mean DS difference, 3.43). The results lend support to the hypothesis that the presence of fluoride in the oral environment promotes lesion arrest rather than inhibiting the initiation of new lesions.

  7. Structural aspects of Judd-Ofelt oscillator strength parameters: relationship between Nd dissolution and its local environment in borosilicate glass

    SciTech Connect

    Li, Hong; Li, Liyu; Strachan, Denis M.

    2005-08-15

    Judd-Ofelt (JO) derived oscillator strength parameters ({Omega}{sub 2}, {Omega}{sub 4}, {Omega}{sub 6}) of electronic transitions of the trivalent lanthanides (Ln) qualitatively describe local Ln environment. Recently, we have systematically studied the parameters, or JO parameters, as a function Nd concentration in a single Na-rich aluminoborosilicate glass. Based on Nd partitioning scheme as its dissolution mechanism for borosilicate glasses, we simulated extent of borate saturation as a function of Nd concentration by applying a stable local Nd-metaborate structure derived from our previous studies. The best results concluded that the first onset of the {Omega}{sub 2} discontinuity resulted from the saturation of the borate sites by Nd. Combining with our earlier study of the JO parameters for Al-rich borosilicate glass without Na, we can further conclude that the index of saturation of boron by Nd, IS{sub [B]} = [Nd{sub 2}O{sub 3}]{sub B-site}/1/3{l_brace}[B{sub 2}O{sub 3}]ex + [Al{sub 2}O{sub 3}]ex{r_brace}, provides a general physical description of Nd partitioning in the borate site for complex Na{sub 2}O-Al{sub 2}O{sub 3}-B{sub 2}O{sub 3}-SiO{sub 2} glasses, whereas for the Na-rich glass reported in this study, [Al{sub 2}O{sub 3}]{sub ex} = 0.

  8. Building the Evidence for Decision-Making: The Relationship Between Local Public Health Capacity and Community Mortality

    PubMed Central

    Meyer, Anne Marie; Kuo, Tzy-Mey; Cilenti, Dorothy

    2015-01-01

    Objectives. We examined associations between local health department (LHD) spending, staffing, and services and community health outcomes in North Carolina. Methods. We analyzed LHD investments and community mortality in North Carolina from 2005 through 2010. We obtained LHD spending, staffing, and services data from the National Association of City and County Health Officials 2005 and 2008 profile surveys. Five mortality rates were constructed using Centers for Disease Control and Prevention mortality files, North Carolina vital statistics data, and census data for LHD service jurisdictions: heart disease, cancer, diabetes, pneumonia and influenza, and infant mortality. Results. Spending, staffing, and services varied widely by location and over time in the 85 North Carolina LHDs. A 1% increase in full-time-equivalent staffing (per 1000 population) was associated with decrease of 0.01 infant deaths per 1000 live births (P < .05). Provision of women and children’s services was associated with a reduction of 1 to 2 infant deaths per 1000 live births (P < .05). Conclusions. Our findings, in the context of other studies, provide support for investment in local public health services to improve community health. PMID:25689215

  9. Observation of a multimode plasma response and its relationship to density pumpout and edge-localized mode suppression

    DOE PAGES

    Paz-Soldan, C.; Nazikian, R.; Haskey, S. R.; ...

    2015-03-12

    Density pumpout and edge-localized mode (ELM) suppression by applied n=2 magnetic fields in low collisionality DIII-D plasmas are shown to be correlated with the magnitude of the plasma response driven on the high field side (HFS) of the magnetic axis, but not the low-field side (LFS) midplane. These distinct responses are a direct measurement of a multi-modal magnetic plasma response, with each structure preferentially excited by a different n=2 applied spectrum and preferentially detected on the LFS or HFS. Ideal and resistive MHD calculations find that the LFS measurement is primarily sensitive to excitation of stable kink modes, while themore » HFS measurement is primarily sensitive to resonant currents (whether fully shielding or partially penetrated). Lastly, the resonant currents are themselves strongly modified by kink excitation, with the optimal applied field pitch for pumpout and ELM suppression significantly differing from equilibrium field-alignment.« less

  10. Characterization of the Distance Relationship Between Localized Serotonin Receptors and Glia Cells on Fluorescence Microscopy Images of Brain Tissue.

    PubMed

    Jacak, Jaroslaw; Schaller, Susanne; Borgmann, Daniela; Winkler, Stephan M

    2015-08-01

    We here present two new methods for the characterization of fluorescent localization microscopy images obtained from immunostained brain tissue sections. Direct stochastic optical reconstruction microscopy images of 5-HT1A serotonin receptors and glial fibrillary acidic proteins in healthy cryopreserved brain tissues are analyzed. In detail, we here present two image processing methods for characterizing differences in receptor distribution on glial cells and their distribution on neural cells: One variant relies on skeleton extraction and adaptive thresholding, the other on k-means based discrete layer segmentation. Experimental results show that both methods can be applied for distinguishing classes of images with respect to serotonin receptor distribution. Quantification of nanoscopic changes in relative protein expression on particular cell types can be used to analyze degeneration in tissues caused by diseases or medical treatment.

  11. Observation of a multimode plasma response and its relationship to density pumpout and edge-localized mode suppression

    SciTech Connect

    Paz-Soldan, C.; Nazikian, R.; Haskey, S. R.; Logan, N. C.; Strait, E. J.; Ferraro, N. M.; Hanson, J. M.; King, J. D.; Lanctot, M. J.; Moyer, R. A.; Okabayashi, M.; Park, J. -K.; Shafer, M. W.; Tobias, B. J.

    2015-03-12

    Density pumpout and edge-localized mode (ELM) suppression by applied n=2 magnetic fields in low collisionality DIII-D plasmas are shown to be correlated with the magnitude of the plasma response driven on the high field side (HFS) of the magnetic axis, but not the low-field side (LFS) midplane. These distinct responses are a direct measurement of a multi-modal magnetic plasma response, with each structure preferentially excited by a different n=2 applied spectrum and preferentially detected on the LFS or HFS. Ideal and resistive MHD calculations find that the LFS measurement is primarily sensitive to excitation of stable kink modes, while the HFS measurement is primarily sensitive to resonant currents (whether fully shielding or partially penetrated). Lastly, the resonant currents are themselves strongly modified by kink excitation, with the optimal applied field pitch for pumpout and ELM suppression significantly differing from equilibrium field-alignment.

  12. Relationship between level of lymph node metastasis and survival in locally advanced head and neck squamous cell carcinoma

    PubMed Central

    Xing, Yan; Zhang, Jianjun; Lin, Heather; Gold, Kathryn A.; Sturgis, Erich M.; Garden, Adam S.; Lee, J. Jack; William, William N.

    2015-01-01

    Background The current head and neck squamous cell carcinoma (HNSCC) staging system may not capture the full prognostic implications of regional lymph node involvement. We sought to investigate the impact of level of lymph node metastasis (LNM) on survival Methods The Surveillance, Epidemiology, and End Results (SEER) registry was queried for oral cavity (OC), oropharynx (OP), larynx (LAR), and hypopharynx (HP) HNSCC. Multivariate Cox proportional hazards model was used to evaluate whether level of LNM is an independent prognostic factor. Site-specific recursive-partitioning analysis (RPA) was performed to classify patients into different risk groups. Results Totally, 14,499 patients including OC (N=2,463), OP (N=8,567), LAR (N=2,332) and HP (N=1,137) were analyzed. Both AJCC N classification and level of LNM showed significant effects on overall survival (OS) in patients with OC, OP or LAR, but not in HP. In patients with N2 disease, AJCC subclassification (N2a, N2b, N2c) was significantly associated with OS of patients with OP and LAR, but not OC or HP, while level of LNM (primary, secondary, and tertiary) was significantly associated with OS in patients with OC, OP and LAR, but not HP. Using RPA, we designed a simple, primary site-specific prognostic tool integrating AJCC T classification, N classification, and level of LNM that can be easily utilized by health care providers in clinic. Conclusions Level of LNM is an independent prognostic factor for patients with locally advanced HNSCC and could add to the prognostic value of AJCC T and N classification in patients with locally advanced HNSCC. PMID:26554754

  13. Local variation in helminth burdens of Egyptian spiny mice (Acomys cahirinus dimidiatus) from ecologically similar sites: relationships with hormone concentrations and social behaviour.

    PubMed

    Barnard, C J; Sayed, E; Barnard, L E; Behnke, J M; Nabi, I Abdel; Sherif, N; Shutt, A; Zalat, S

    2003-09-01

    Populations of Egyptian spiny mice (Acomys cahirinus dimidiatus) in a fragmented montane wadi system in the Sinai showed significant differences in the abundance of gut helminths. Differences in parasite load between populations were positively associated with measures of androgen activity but showed no significant relationship with glucocorticoid activity. Social discrimination tests with adult males from different wadis showed that those from sites with greater helminth abundance were less likely to investigate odours from other males and were less aggressive when subsequently interacting with the odour donors. Subjects showed markedly more investigation towards the odours of males from distant wadis compared with those from their own or immediately neighbouring wadi, but were less aggressive when confronted with odour donors from distant wadis. Despite this, there was a positive relationship between the amount of investigation towards distant male odour and subsequent aggression towards the male. While aggressiveness was positively associated with measures of androgen and glucocorticoid activity, no significant relationship emerged with individual helminth infection. Thus aggressiveness appeared to relate to overall local population levels of infection rather than individual challenge.

  14. Analysis of the relationship between periodontal disease and atherosclerosis within a local clinical system: a cross-sectional observational pilot study.

    PubMed

    Kudo, Chieko; Shin, Wee Soo; Minabe, Masato; Harai, Kazuo; Kato, Kai; Seino, Hiroaki; Goke, Eiji; Sasaki, Nobuhiro; Fujino, Takemasa; Kuribayashi, Nobuichi; Pearce, Youko Onuki; Taira, Masato; Maeda, Hiroshi; Takashiba, Shogo

    2015-09-01

    It has been revealed that atherosclerosis and periodontal disease may have a common mechanism of "chronic inflammation". Several reports have indicated that periodontal infection is related to atherosclerosis, but none have yet reported such an investigation through the cooperation of local clinics. This study was performed in local Japanese clinics to examine the relationship between periodontal disease and atherosclerosis under collaborative medical and dental care. A pilot multicenter cross-sectional study was conducted on 37 medical patients with lifestyle-related diseases under consultation in participating medical clinics, and 79 periodontal patients not undergoing medical treatment but who were seen by participating dental clinics. Systemic examination and periodontal examination were performed at baseline, and the relationships between periodontal and atherosclerosis-related clinical markers were analyzed. There was a positive correlation between LDL-C level and plasma IgG antibody titer to Porphyromonas gingivalis. According to the analysis under adjusted age, at a cut-off value of 5.04 for plasma IgG titer to Porphyromonas gingivalis, the IgG titer was significantly correlated with the level of low-density lipoprotein cholesterol (LDL-C). This study suggested that infection with periodontal bacteria (Porphyromonas gingivalis) is associated with the progression of atherosclerosis. Plasma IgG titer to Porphyromonas gingivalis may be useful as the clinical risk marker for atherosclerosis related to periodontal disease. Moreover, the application of the blood examination as a medical check may lead to the development of collaborative medical and dental care within the local medical clinical system for the purpose of preventing the lifestyle-related disease.

  15. Population-Based Screening for Selective Immunoglobulin A (IgA) Deficiency in Lithuanian Children Using a Rapid Antibody-Based Fingertip Test

    PubMed Central

    Urbonas, Vaidotas; Sadauskaite, Jolita; Cerkauskiene, Rimante; Kaminskas, Arvydas; Mäki, Markku; Kurppa, Kalle

    2016-01-01

    Background Selective immunoglobulin A (IgA) deficiency is the most common inherited immunodeficiency disorder world-wide. An early diagnosis is advocated because of the increased risk of infections, autoimmune diseases, and allergic reactions. We investigated the usefulness of a rapid point-of-care test in detecting for IgA deficiency in a population with a previously unknown prevalence. Material/Methods Altogether, 1000 children aged 11–13 years from randomly selected Lithuanian schools were enrolled. A point-of-care test with a fingertip sample was used to screen for the presence of IgA deficiency in children whose parents gave consent. Those with suspected IgA deficiency were referred to hospital for further clinical examination and confirmation of the diagnosis. In addition, their medical histories were compared with those of 30 age- and sex-matched healthy controls. Results IgA deficiency was suspected in one girl and in three boys on the basis of the rapid test, and the diagnosis was confirmed for all four cases (prevalence 0.4%, 95% confidence interval 0.16–1.02%). There was no difference in disease history or complications between IgA-deficient children and healthy controls. Conclusions The rapid antibody test is a practical and accurate method to diagnose selective IgA deficiency in children. The prevalence of IgA deficiency among Lithuanian schoolchildren is 1:250. PMID:27920422

  16. Relationships among subgross anatomy, computed tomography, and histologic findings in dogs with disease localized to the pulmonary acini.

    PubMed

    Scrivani, Peter V; Thompson, Margret S; Dykes, Nathan L; Holmes, Nedra L; Southard, Teresa L; Gerdin, Jodie A; Bezuidenhout, Abraham J

    2012-01-01

    During computed tomography (CT), the appearance of disease involving the pulmonary acinus may be described using terms such as atelectasis, ground-glass opacity, or consolidation. These CT signs, however, have not been correlated with histologic findings in canine pulmonary disease. To facilitate interpretation of lung diseases by CT signs, our goals were to review the morphologic organization of the lung and evaluate the medical records of four dogs with different types of pulmonary acinar disease. Anatomic review focused on understanding the pulmonary acinus and the secondary pulmonary lobule; the secondary pulmonary lobule is a fundamental unit for interpretation in people. All dogs had similar CT findings of fully expanded lungs with increased attenuation and partial-to-complete obscuring of the pulmonary blood vessels. Histologic findings varied between dogs and included partial-to-complete filling of airspaces with cells or fluid, interstitial thickening, increased capillary blood volume, or a combination of these findings. Final diagnoses were hemorrhagic pneumonia, bronchiolar carcinoma, metastatic mammary adenocarcinoma, and pulmonary edema. In summary, the morphologic organization of the lungs is complex and has implications for diagnostic interpretation needing further evaluation in dogs. In this study, increased lung attenuation during CT due to disease localized to the pulmonary acini was due to the displacement of air from the lungs and not to the microscopic distribution of lesions within the pulmonary acinus. Imaging descriptors that classify diseases according to structures larger than the pulmonary acini, for example, regions of the secondary pulmonary lobule or larger, may be appropriate for dogs.

  17. Unforced surface air temperature anomalies and their opposite relationship with the TOA energy imbalance at local and global scales

    NASA Astrophysics Data System (ADS)

    Brown, P. T.; Li, W.; Jiang, J. H.; Su, H.

    2015-12-01

    Unforced global mean surface air temperature (Tglobal) is stable in the long-term primarily because warm Tglobal anomalies are associated with enhanced outgoing longwave radiation to space and thus a negative global radiative energy imbalance (Nglobal, positive downward) at the top of the atmosphere (TOA). However, it is shown here that at the local spatial scale, warm unforced Tlocal anomalies tend to be associated with anomalously positive Nlocal imbalances over most of the surface of the planet. It is revealed that this occurs mainly because warm Tlocal anomalies are accompanied by anomalously low surface albedo near sea ice margins and over high altitudes, anomalously low cloud albedo over much of the mid/low-latitudes and an anomalously large water-vapor greenhouse effect over the deep tropical ocean. During warm Tglobal years, the largest negative Nlocal anomalies primarily occur over regions of cool or near-neutral Tlocal anomalies. These results help explain how TOA energy imbalances can act to damp unforced Tglobal anomalies while simultaneously amplifying unforced Tlocal anomalies.

  18. Relationship between localization of gold mining areas and hair mercury levels in people from Bolivar, north of Colombia.

    PubMed

    Olivero-Verbel, Jesús; Caballero-Gallardo, Karina; Marrugo Negrete, Jose; Negrete-Marrugo, José

    2011-12-01

    Mercury (Hg) is a heavy metal that, once in the environment, is bioaccumulated and biomagnified through food chain impacting ecosystems. The aim of this study was to evaluate total Hg (T-Hg) concentrations in individuals along Cauca and Magdalena Rivers in Colombia, where most gold mining activities take place. A total of 1,328 hair samples were collected and analyzed for T-Hg using atomic absorption spectroscopy. T-Hg concentrations ranged from 0.01 to 20.14 μg/g. Greatest levels were detected in La Raya (5.27 ± 0.32 μg/g), Achi (2.44 ± 0.22 μg/g), and Montecristo (2.20 ± 0.20 μg/g), places that are located near gold mines. Concentrations decreased with the distance from main mining areas. Only 0.75% of the individuals had T-Hg levels above 10 μg/g. Men had significantly higher T-Hg levels than women, and correlation analysis revealed moderately weak but significant relationships between T-Hg and weight (R = 0.111, P < 0.001), stature (R = 0.111, P < 0.001), and age (R = 0.073, P = 0.007). However, T-Hg concentrations did not vary according to fish consumption frequency. Subjective health survey showed no Hg-related signs or symptoms within studied sample. However, studies are necessary to detect neurological damage linked to the metal. Changing technologies to Hg-free mining, monitoring, and educational programs are necessary to protect health of people living near Colombian rivers.

  19. The relationship between exercise-induced muscle fatigue, arterial blood flow and muscle perfusion after 56 days local muscle unloading.

    PubMed

    Weber, Tobias; Ducos, Michel; Mulder, Edwin; Beijer, Åsa; Herrera, Frankyn; Zange, Jochen; Degens, Hans; Bloch, Wilhelm; Rittweger, Jörn

    2014-05-01

    In the light of the dynamic nature of habitual plantar flexor activity, we utilized an incremental isokinetic exercise test (IIET) to assess the work-related power deficit (WoRPD) as a measure for exercise-induced muscle fatigue before and after prolonged calf muscle unloading and in relation to arterial blood flow and muscle perfusion. Eleven male subjects (31 ± 6 years) wore the HEPHAISTOS unloading orthosis unilaterally for 56 days. It allows habitual ambulation while greatly reducing plantar flexor activity and torque production. Endpoint measurements encompassed arterial blood flow, measured in the femoral artery using Doppler ultrasound, oxygenation of the soleus muscle assessed by near-infrared spectroscopy, lactate concentrations determined in capillary blood and muscle activity using soleus muscle surface electromyography. Furthermore, soleus muscle biopsies were taken to investigate morphological muscle changes. After the intervention, maximal isokinetic torque was reduced by 23·4 ± 8·2% (P<0·001) and soleus fibre size was reduced by 8·5 ± 13% (P = 0·016). However, WoRPD remained unaffected as indicated by an unchanged loss of relative plantar flexor power between pre- and postexperiments (P = 0·88). Blood flow, tissue oxygenation, lactate concentrations and EMG median frequency kinematics during the exercise test were comparable before and after the intervention, whereas the increase of RMS in response to IIET was less following the intervention (P = 0·03). In conclusion, following submaximal isokinetic muscle work exercise-induced muscle fatigue is unaffected after prolonged local muscle unloading. The observation that arterial blood flow was maintained may underlie the unchanged fatigability.

  20. Significant relationship between local angle at fused segments and C2-7 angle: Average duration of longer than 20 years after anterior cervical discectomy and fusion

    PubMed Central

    Nagata, T.; Takami, T.; Yamagata, T.; Uda, T.; Naito, K.; Ohata, K.

    2011-01-01

    Background: The authors have focused their attention to the radiological durability of cervical sagittal alignment after anterior cervical discectomy and fusion (ACDF) using autologous bone grafting. Materials and Methods: Among the patients who underwent ACDF with trans-unco-discal (TUD) approach between 1976 and 1997, 22 patients (16 males and 6 females) made return visits for a clinical evaluation. Patients with trauma or previously treated by anterior cervical fusion or by posterior decompression were excluded from the present study. Clinical evaluation included adjacent segment degeneration (ASD), osseous fusion, local angle at the fused segments and C2-7 angle of cervical spine. Results: The duration after ACDF ranged from 13 to 34 years with an average of 21.3 ± 7.0 years. A single level fusion was done on 8 patients, 2 levels on 11 patients, 3 levels on 2 patients, and 4 levels on 1 patient. Imaging studies indicated that 12 of the 22 patients (54.5%) were graded as having symptomatic ASD. Osseous bony fusion at ACDF was recognized in all cases. None of the patients demonstrated kyphotic malalignment of the cervical spine. Average degrees of local angle at the fused segments and the C2-7 angle were 7.06 and 17.6, respectively. Statistical analysis indicated a significant relationship between the local at the fused segments and C2-7 angles. Conclusions: Sagittal alignment of the cervical spine was durable long after ACDF when the local angle at the fused segments was well stabilized. PMID:23125490

  1. B-cell lymphoma-2 localization in the female reproductive tract of the Chinese soft-shelled turtle, Pelodiscus sinensis and its relationship with sperm storage.

    PubMed

    Le, Yuan; Chen, Shaofan; Hu, Lisi; Zhang, Linli; Ullah, Shakeeb; Liu, Tengfei; Yang, Ping; Liu, Yi; Chen, Qiusheng

    2015-12-01

    The aim of the present study was to investigate the expression and localization of B-cell lymphoma-2 (Bcl-2) in the oviduct of the Chinese soft-shelled turtle, Pelodiscus sinensis, during the reproductive cycle to analyze the relationship between Bcl-2 and sperm storage. Bcl-2 expression was confirmed in the P. sinensis oviduct by western blot analysis. Hematoxylin-eosin staining showed that female P. sinensis stored sperm from November to April of the following year. The oviduct showed positive immunostaining for Bcl-2 of epithelial ciliated cells, gland ducts, and gland cells. Bcl-2 expression in the oviduct was associated with sperm storage occurrence. This indicates that the survival factor Bcl-2 may play a role in P. sinensis sperm storage.

  2. Three-dimensional ultrastructural analyses of anterior pituitary gland expose spatial relationships between endocrine cell secretory granule localization and capillary distribution.

    PubMed

    Yoshitomi, Munetake; Ohta, Keisuke; Kanazawa, Tomonoshin; Togo, Akinobu; Hirashima, Shingo; Uemura, Kei-Ichiro; Okayama, Satoko; Morioka, Motohiro; Nakamura, Kei-Ichiro

    2016-10-31

    Endocrine and endothelial cells of the anterior pituitary gland frequently make close appositions or contacts, and the secretory granules of each endocrine cell tend to accumulate at the perivascular regions, which is generally considered to facilitate secretory functions of these cells. However, three-dimensional relationships between the localization pattern of secretory granules and blood vessels are not fully understood. To define and characterize these spatial relationships, we used scanning electron microscopy (SEM) three-dimensional reconstruction method based on focused ion-beam slicing and scanning electron microscopy (FIB/SEM). Full three-dimensional cellular architectures of the anterior pituitary tissue at ultrastructural resolution revealed that about 70% of endocrine cells were in apposition to the endothelial cells, while almost 30% of endocrine cells were entirely isolated from perivascular space in the tissue. Our three-dimensional analyses also visualized the distribution pattern of secretory granules in individual endocrine cells, showing an accumulation of secretory granules in regions in close apposition to the blood vessels in many cases. However, secretory granules in cells isolated from the perivascular region tended to distribute uniformly in the cytoplasm of these cells. These data suggest that the cellular interactions between the endocrine and endothelial cells promote an uneven cytoplasmic distribution of the secretory granules.

  3. Three-dimensional ultrastructural analyses of anterior pituitary gland expose spatial relationships between endocrine cell secretory granule localization and capillary distribution

    PubMed Central

    Yoshitomi, Munetake; Ohta, Keisuke; Kanazawa, Tomonoshin; Togo, Akinobu; Hirashima, Shingo; Uemura, Kei-ichiro; Okayama, Satoko; Morioka, Motohiro; Nakamura, Kei-ichiro

    2016-01-01

    Endocrine and endothelial cells of the anterior pituitary gland frequently make close appositions or contacts, and the secretory granules of each endocrine cell tend to accumulate at the perivascular regions, which is generally considered to facilitate secretory functions of these cells. However, three-dimensional relationships between the localization pattern of secretory granules and blood vessels are not fully understood. To define and characterize these spatial relationships, we used scanning electron microscopy (SEM) three-dimensional reconstruction method based on focused ion-beam slicing and scanning electron microscopy (FIB/SEM). Full three-dimensional cellular architectures of the anterior pituitary tissue at ultrastructural resolution revealed that about 70% of endocrine cells were in apposition to the endothelial cells, while almost 30% of endocrine cells were entirely isolated from perivascular space in the tissue. Our three-dimensional analyses also visualized the distribution pattern of secretory granules in individual endocrine cells, showing an accumulation of secretory granules in regions in close apposition to the blood vessels in many cases. However, secretory granules in cells isolated from the perivascular region tended to distribute uniformly in the cytoplasm of these cells. These data suggest that the cellular interactions between the endocrine and endothelial cells promote an uneven cytoplasmic distribution of the secretory granules. PMID:27796315

  4. The Relationship between Local Economic Conditions and Acute Myocardial Infarction Hospital Utilization by Adults and Seniors in the United States, 1995–2011

    PubMed Central

    Carls, Ginger Smith; Henke, Rachel Mosher; Karaca, Zeynal; Marder, William D; Wong, Herbert S

    2015-01-01

    Objective To assess the association between aggregate unemployment and hospital discharges for acute myocardial infarction (AMI) among adults and seniors, 1995–2011. Data Sources/Study Setting Community hospital discharge data from states collected for the Healthcare Cost and Utilization Project (HCUP) State Inpatient Databases (SID) and economic data from the Bureau of Labor Statistics, 1995–2011. Study Design Quarterly time series study of unemployment and aggregate hospital discharges in local areas using fixed effects to control for differences between local areas. Data Collection/Extraction Methods Secondary data on inpatient stays and unemployment rates aggregated to micropolitan and metropolitan areas. Principal Findings For both adults and seniors, a 1 percentage point increase in the contemporaneous unemployment rate was associated with a statistically significant 0.80 percent (adults) to 0.96 percent (seniors) decline in AMI hospitalization during the first half of the study but was unrelated to the economic cycle in the second half of the study period. Conclusions The study found evidence that the aggregate relationship between health and the economy may be shifting for cardiovascular events, paralleling recent research that has shown a similar shift for some types of mortality (Ruhm 2013), self-reported health, and inpatient use among seniors (McInerney and Mellor 2012). PMID:25772510

  5. Sulfide-Sulfate Mineralizations in Verzino Area (Crotone Basin, Southern Italy): New insights on localized hydrothermal fluid circulations and their relationship with tectonics.

    NASA Astrophysics Data System (ADS)

    Berardi, Gabriele; Lucci, Federico; Cozzupoli, Domenico; Pizzino, Luca; Cantucci, Barbara; Quattrocchi, Fedora

    2010-05-01

    In this early stage of the work we present a preliminary study of hydrothermal mineralizations found in Verzino locality, Crotone Basin, Southern Appennines, (Calabria, Italy). Both geochemical and petrographic investigations were developed with the aim of understanding the genesis of the sulfide-sulfate associations present in the "Argille Marnose del Ponda" formation, deepening their relationship with fluids circulation. These mineralizations have been recognized only in two "Calanchi" morphostructures - Badlands like morphology developed by the differential erosional pattern of the "Argille Marnose del Ponda" fm. - and constituting the northwestern flank of a little valley evolved in the Miocene sedimentary sequence from "Conglomerato di S.Nicola" fm. to "Evaporiti Superiori" fm. The mineralizations are distributed along isooriented centimetric veins (with mean direction of N120) and in nodules diffused close to the veins. These hydrothermal mineralizations are constituted by an associations of Pyrite spherical nodules (millimetric to centimetric in radius with occurrences of well developed octahedral habit single crystals), sulphate crystals (Gypsum, Jarosite, NatroJarosite), Oxides (Goethite mainly), millimetric veins of Barite and micrometric Ankerite specimens. The data (mineral habits, semiquantitative compositions and x-Ray spectra), obtained by an integration of S.E.M and XRD investigations, permit us, at the current stage of the study, to hypothesize a possible hydrothermal origin (whose temperature range estimate needs further investigations) for the sulfide-sulfate mineral phases. At the moment, we exclude their primary or secondary sedimentary provenance. The comparison of our results with the previous scientific literature focused on hydrothermal sulfide-sulfate systems (Vinogradov and Stephanov, 1964; Kostov, 1968; Plummer 1971; Boles, 1978; Ferrini and Moretti 1998) allows us to propose a possible "thermal window" ranging in the interval 50°C-230

  6. Building Relationships with Local Media

    ERIC Educational Resources Information Center

    Kidwai, Sabrina

    2007-01-01

    One of ACTE's goals is to improve the image of career and technical education (CTE) through outreach to the media. As media relations manager, the author receives calls from reporters asking questions about the types of students who participate in CTE. Reporters often have a misconception that CTE students are troubled or "at the bottom of the…

  7. Did the ambient ozone affect stem increment of Scots Pines (Pinus sylvestris L.) on territories under regional pollution load? Step III of Lithuanian studies.

    PubMed

    Augustaitis, Algirdas; Augustaitiene, Ingrida; Cinga, Gintautas; Mazeika, Juozapas; Deltuvas, Romualdas; Juknys, Romualdas; Vitas, Adomas

    2007-03-21

    This study aimed to explore if changes in stem increment of Scots pines (Pinus sylvestris L.) could be related to changes in ambient ozone concentration when the impact of tree dendrometric parameters (age, diameter) and crown defoliation are accounted for. More than 200 dominant and codominant trees from 12 pine stands, for which crown defoliation had been assessed since 1994, were chosen for increment boring and basal area increment computing. Stands are located in Lithuanian national parks, where since 1994-95 Integrated Monitoring Stations have been operating. Findings of the study provide statistical evidence that peak concentrations of ambient ozone (O3) can have a negative impact on pine tree stem growth under field conditions where O3 exposure is below phytotoxic levels.

  8. Assessing oil spill sensitivity in unsheltered coastal environments: A case study for Lithuanian-Russian coasts, South-eastern Baltic Sea.

    PubMed

    Depellegrin, Daniel; Pereira, Paulo

    2016-01-15

    This study presents a series of oil spill indexes for the characterization of physical and biological sensitivity in unsheltered coastal environments. The case study extends over 237 km of Lithuanian-Russian coastal areas subjected to multiple oil spill threats. Results show that 180 km of shoreline have environmental sensitivity index (ESI) of score 3. Natural clean-up processes depending on (a) shoreline sinuosity, (b) orientation and (c) wave exposure are favourable on 72 km of shoreline. Vulnerability analysis from pre-existing Kravtsovskoye D6 platform oil spill scenarios indicates that 15.1 km of the Curonian Spit have high impact probability. The highest seafloor sensitivity within the 20 m isobath is at the Vistula Spit and Curonian Spit, whereas biological sensitivity is moderate over the entire study area. The paper concludes with the importance of harmonized datasets and methodologies for transboundary oil spill impact assessment.

  9. Relationship Between Radiation Treatment Time and Overall Survival After Induction Chemotherapy for Locally Advanced Head-and-Neck Carcinoma: A Subset Analysis of TAX 324

    SciTech Connect

    Sher, David J.; Posner, Marshall R.; Sarlis, Nicholas J.; Haddad, Robert I.; Holupka, Edward J.; Devlin, Phillip M.

    2011-12-01

    Purpose: To analyze the relationship between overall survival (OS) and radiation treatment time (RTT) and overall treatment time (OTT) in a well-described sequential therapy paradigm for locally advanced head-and-neck carcinoma (LAHNC). Methods and Materials: TAX 324 is a Phase III study comparing TPF (docetaxel, cisplatin, and fluorouracil) with PF (cisplatin and fluorouracil) induction chemotherapy (IC) in LAHNC patients; both arms were followed by carboplatin-based chemoradiotherapy (CRT). Prospective radiotherapy quality assurance was performed. This analysis includes all patients who received three cycles of IC and a radiation dose of {>=} 70 Gy. Radiotherapy treatment time was analyzed as binary ({<=} 8 weeks vs. longer) and continuous (number of days beyond 8 weeks) functions. The primary analysis assessed the relationship between RTT, OTT, and OS, and the secondary analysis explored the association between treatment times and locoregional recurrence (LRR). Results: A total of 333 (of 501) TAX 324 patients met the criteria for inclusion in this analysis. There were no significant differences between the treatment arms in baseline or treatment characteristics. On multivariable analysis, PF IC, World Health Organization performance status of 1, non-oropharynx site, T3/4 stage, N3 status, and prolonged RTT (hazard ratio 1.63, p = 0.006) were associated with significantly inferior survival. Performance status, T3/4 disease, and prolonged RTT (odds ratio 1.68, p = 0.047) were independently and negatively related to LRR on multivariable analysis, whereas PF was not. Overall treatment time was not independently associated with either OS or LRR. Conclusions: In this secondary analysis of the TAX 324 trial, TPF IC remains superior to PF IC after controlling for radiotherapy delivery time. Even with optimal IC and concurrent chemotherapy, a non-prolonged RTT is a crucial determinant of treatment success. Appropriate delivery of radiotherapy after IC remains essential

  10. Urinary Obstruction in Prostate Cancer Patients From the Dutch Trial (68 Gy vs. 78 Gy): Relationships With Local Dose, Acute Effects, and Baseline Characteristics

    SciTech Connect

    Heemsbergen, Wilma D.; Al-Mamgani, Abrahim; Witte, Marnix G.; Herk, Marcel van; Pos, Floris J.; Lebesque, Joos V.

    2010-09-01

    Purpose: To investigate the relationship between late urinary obstruction and the details of the dose distribution of irradiated prostate cancer patients, taking into account their baseline symptoms and acute complaints. Patients and Methods: We selected patients from the Dutch multicenter trial randomized between 68 Gy and 78 Gy, for whom toxicity data and dose data were available (n = 557). The absolute dose surface parameters of the delineated bladder were calculated. Next, we constructed three-dimensional dose maps of the area around the prostate, providing an approximate identification of the corresponding anatomic locations. The dose difference maps were constructed by subtracting the mean dose maps of the patients with and without late urinary obstruction. Selected local dose points were analyzed using Cox regression analysis. Results: Urinary obstruction was scored for 40 patients, including 19 of 296 patients who received 68-72 Gy and 21 of 261 patients who received 76-78 Gy. A total of 19 events occurred within 2 years after irradiation and 21 events after 2 years. The bladder surface receiving {>=}80 Gy predicted (p <.01) the occurrence of obstruction within 2 years. The dose difference map indicated highly significant differences in the bladder neck situated in the trigonal region (p < .001) that were especially predictive of obstruction after 2 years and of the diagnosis of bladder neck obstruction. Baseline complaints and transurethral resection of the prostate and acute complaints were mainly predictive for obstruction within 2 years. Conclusion: Relatively early events of urinary obstruction were associated with urinary problems existing before RT, acute toxicity, previous transurethral resection of the prostate, and hotspots in the bladder. Events after 2 years were associated with the local dose in the trigonal area.

  11. Evaluation of Relationships among Occupational Stress, Alcohol Dependence and Other Factors in Male Personnel in a Japanese Local Fire Fighting Organization

    PubMed Central

    Hosoda, Takenobu; Osaki, Yoneatsu; Okamoto, Hiroteru; Wada, Takako; Otani, Shinji; Mu, Haosheng; Yokoyama, Yae; Okamoto, Mikizo; Kurozawa, Youichi

    2012-01-01

    Recent large-scale disasters have made middle-ranked fire defense officers responsible for routine fire fighting activities, and a tendency of alcohol dependence associated with other stressful problems is noted in Japan. We assessed the alcohol dependence tendency with the alcohol use disorders identification test (AUDIT) in firefighters. Occupational stress, depression and other factors were evaluated with the brief job stress questionnaire, Center for Epidemiologic Studies depression scale, K10 and a face sheet. Subjects were 294 male personnel in a local fire defense headquarters, and 246 of them (83.4%) answered effectively. Data were analyzed first with univariate analysis between the AUDIT score and other items, and then with multivariate analysis of the AUDIT score as a dependent variable and other items as independent variables. The AUDIT score (mean ± SD) in the 246 respondents classified by age ranges was 7.9 ± 5.4 points (the lowest, 0 points; the highest, 27 points). The multivariate analysis showed significant correlations of the AUDIT score with the workplace environment (P = 0.003) and the rank of work (P = 0.019). The present survey was cross-sectional, and we could not clarify the subjects’ past drinking states and applicability of the results to the whole Japan personnel. It is necessary to further investigate the relationship between alcoholism and depression in the present subjects. As a pilot study, we first clarified the state of alcohol dependence in personnel in a Japanese local fire fighting organization, and examined related factors. PMID:24031141

  12. The relationship among complex fractionated electrograms, wavebreak, phase singularity, and local dominant frequency in fibrillation wave-dynamics: a modeling comparison study.

    PubMed

    Yun, Yonghyeon; Hwang, Minki; Park, Jae Hyung; Shin, Hangsik; Shim, Eun Bo; Pak, Hui-Nam

    2014-03-01

    Although complex fractionated electrogram (CFE) is known to be a target for catheter ablation of fibrillation, its physiological meaning in fibrillation wave-dynamics remains to be clarified. We evaluated the spatiotemporal relationships among the parameters of fibrillation wave-dynamics by simulation modeling. We generated maps of CFE-cycle length (CFE-CL), local dominant frequency (LDF), wave break (WB), and phase singularity (PS) of fibrillation in 2-dimensional homogeneous bidomain cardiac modeling (1,000 × 1,000 cells ten Tusscher model). We compared spatiotemporal correlations by dichotomizing each maps into 10 × 10 lattice zones. In spatial distribution, WB and PS showed excellent correlation (R = 0.963, P < 0.001). CFE-CL had weak correlations with WB (R = 0.288, P < 0.001), PS (R = 0.313, P < 0.001), and LDF (R = -0.411, P < 0.001). However, LDF did not show correlation with PS or WB. PSs were mostly distributed at the periphery of low CFE-CL area. Virtual ablation (5% of critical mass) of CFE-CL < 100 ms terminated fibrillation at 14.3 sec, and high LDF ablation (5% of critical mass) changed fibrillation to organized tachycardia, respectively. In homogeneous 2D fibrillation modeling, CFE-CL was weakly correlated with WB, PS, and LDF, spatiotemporally. PSs are mostly positioned at the periphery of low CFE-CL areas, and virtual ablation targeting low CFE-CL regions terminated fibrillation successfully.

  13. The aftermath of public housing relocations: relationships between changes in local socioeconomic conditions and depressive symptoms in a cohort of adult relocaters.

    PubMed

    Cooper, Hannah L F; Hunter-Jones, Josalin; Kelley, Mary E; Karnes, Conny; Haley, Danielle F; Ross, Zev; Rothenberg, Richard; Bonney, Loida E

    2014-04-01

    USA is experiencing a paradigm shift in public housing policy: while policies used to place people who qualified for housing assistance into spatially concentrated housing complexes, they now seek to geographically disperse them, often to voucher-subsidized rental units in the private market. Programs that relocate residents from public housing complexes tend to move them to neighborhoods that are less impoverished and less violent. To date, studies have reached conflicting findings about the relationship between public housing relocations and depression among adult relocaters. The present longitudinal multilevel analysis tests the hypothesis that pre-/postrelocation improvements in local economic conditions, social disorder, and perceived community violence are associated with declines in depressive symptoms in a cohort of African-American adults; active substance misusers were oversampled. We tested this hypothesis in a cohort of 172 adults who were living in one of seven public housing complexes scheduled for relocation and demolition in Atlanta, GA; by design, 20% were dependent on substances and 50% misused substances but were not dependent. Baseline data captured prerelocation characteristics of participants; of the seven census tracts where they lived, three waves of postrelocation data were gathered approximately every 9 months thereafter. Surveys were administered at each wave to assess depressive symptoms measured using the Center for Epidemiologic Studies Depression Scale (CES-D), perceived community violence, and other individual-level covariates. Participants' home addresses were geocoded to census tracts at each wave, and administrative data sources were used to characterize tract-level economic disadvantage and social disorder. Hypotheses were tested using multilevel models. Between waves 1 and 2, participants experienced significant improvements in reported depressive symptoms and perceived community violence and in tract-level economic disadvantage

  14. [Differences in allele frequency at the BAIB locus, determining the level of expression of beta-aminoisobutyric acid, in healthy donors and coronary artery atherosclerosis patients from Buryat and Lithuanian populations].

    PubMed

    Spitsyn, V A; Afanas'eva, I S

    2001-12-01

    Phenotype and allele frequencies of the genetically dimorphic system determining urinary excretion of beta-aminoisobutyric acid (BAIB) were studied in population samples of Buryats from the Aginskii Buryat Autonomous District and Lithuanians from Vilnius and in patients with coronary atherosclerosis (CA) from both populations. Frequency of allele BAIB*b, which determines high BAIB excretion, proved to be more than twice higher in Buryats compared with the population sample of Lithuanians (0.620 versus 0.289, respectively). The proportion of individuals with high BAIB excretion in CA patients of either ethnic sample was twice higher than in the corresponding control sample. Frequency of allele BAIB*b in CA patients and healthy individuals was 0.348 and 0.242, respectively, in the Lithuanian population and 0.775 and 0.557, respectively, in the Buryat population. Thus, assessment of urinary excretion of BAIB proved to be prognostically valuable. The method used to detect a variation in BAIB excretion is relatively inexpensive, simple, and suitable for mass screening of patients and healthy individuals (population control). After additional testing with representative samples, the method can be used as an accessory diagnostic test in patients with cardiovascular disorders.

  15. Variation in stable isotope ratios of monthly rainfall in the Douala and Yaounde cities, Cameroon: local meteoric lines and relationship to regional precipitation cycle

    NASA Astrophysics Data System (ADS)

    Wirmvem, Mengnjo Jude; Ohba, Takeshi; Kamtchueng, Brice Tchakam; Taylor, Eldred Tunde; Fantong, Wilson Yetoh; Ako, Ako Andrew

    2016-04-01

    Hydrogen (D) and oxygen (18O) stable isotopes in precipitation are useful tools in groundwater recharge and climatological investigations. This study investigated the isotopes in rainfall during the 2013 and 2014 hydrological years in the Douala and Yaounde urban cities. The objectives were to generate local meteoric water lines (LMWLs), define the spatial-temporal variations of the isotopes in rainwater and their relationship to the regional precipitation cycle, and determine the factors controlling the isotopic variation. The LWMLs in Douala and Yaounde were δD = 7.92δ18O + 12.99 and δD = 8.35δ18O + 15.29, respectively. The slopes indicate isotopic equilibrium conditions during rain formation and negligible evaporation effect during rainfall. Precipitation showed similar wide ranges in δ18O values from -5.26 to -0.75 ‰ in Douala and -5.8 to +1.81 ‰ in Yaounde suggesting a common moisture source from the Atlantic Ocean. Enriched weighted mean δ18O (wδ18O) values during the low pre- and post-monsoon showers coincided with low convective activity across the entire region. Enriched isotopic signatures also marked the West African monsoon transition phase during each hydrological year. Abrupt wδ18O depletion after the transition coincided with the monsoon onset in the region. Peak periods of monsoonal rainfall, associated with high convective activities, were characterised by the most depleted wδ18O values. Controls on isotopic variations are the amount effect and moisture recycling. The stable isotope data provide a tool for groundwater recharge studies while the isotopic correlation with regional rainfall cycle demonstrate their use as markers of moisture circulation and detecting climatic changes in precipitation.

  16. Retrospective analysis of age-adjusted body mass index among pre-pregnant women in the Lithuanian urban area during three decades

    PubMed Central

    Francaite-Daugeliene, Migle; Petrenko, Vladimiras; Baliutaviciene, Dalia; Velickiene, Dzilda

    2016-01-01

    Background The prevalence of maternal obesity at the beginning of pregnancy is increasing. However, there are some studies reporting the stabilisation of obesity epidemic or even the downward trend in the general population. Objective To determine the prevalence of overweight and obesity in Lithuanian pre-pregnant women during 3 decades. Methods This observational retrospective study included a sample of 2827, women aged 18–44 years who gave birth in 1987–1989, 1996–1997 and 2007–2010: 861 (30.5%), 995 (35.2%) and 971 (34.3%), respectively. All women were divided into groups by body mass index (BMI) calculated from self-reported weight and height, and age reported during the first antenatal visit. Quantitative parametric variables were expressed as mean and SD; qualitative variables, as absolute numbers (n) and percentage (%). For parametric data, analysis of variance (ANOVA) was used. Differences were considered statistically significant at p<0.05. Results The prevalence of overweight and obesity among women aged 18–24 years decreased from 20.9% in 1987–1989 to 9.5% in 1996–1997 but increased to 15.7% in 2007–2010; among women aged 25–34 years, decreased from 35.5% in 1987–1989 to 23% in 1996–1997 and to 22.4% in 2007–2010; and among women aged 35–44 years decreased from 64.9% in 1987–1989 to 34% in 1996–1997 but increased to 45.3% in 2007–2010. BMI increased with an increasing age (r=0.254, p<0.05). Analysis by separate periods (1987–1989, 1996–1997 and 2007–2010) revealed a positive correlation between BMI and age at the first antenatal visit in all periods (r=0.325, p<0.01; r=0.266, p<0.01; and r=0.210, p<0.01, respectively). Conclusions The prevalence of overweight and obesity among pre-pregnant women tended to decrease in the Lithuanian urban area during 3 decades. A slight increase in overweight and obesity documented in 2007–2010 compared with 1996–1997 most likely was caused by older maternal age. PMID

  17. Assessment of the relationship between bacteriological quality of dug-wells, hygiene behaviour and well characteristics in two cholera endemic localities in Douala, Cameroon

    PubMed Central

    2013-01-01

    Background Access to potable water is grossly inadequate in Douala-Cameroon. The situation is worse in slum areas, compelling inhabitants to obtain water from sources of doubtful quality. This has contributed to frequent outbreaks of water-borne diseases particularly cholera, which results in severe morbidity and mortality. Shallow wells are a major source of water in these areas. We analyzed the influence of some factors on the bacteriological quality of well water in Bepanda and New Bell, cholera endemic localities in Douala to generate data that would serve as basis for strengthening of water and health policies. Methods Questionnaires were administered to inhabitants of study sites to appraise their hygiene and sanitation practices, and level of awareness of waterborne diseases. The bacteriological quality of water was determined by investigating bacterial indicators of water quality. Relationship between well characteristics and bacteriological quality of water was determined using χ2 test. The Kendall tau_b nonparametric correlation was used to measure the strength of association between well characteristics and bacteriological parameters. Statistics were discussed at 95% confidence level. Antibiotic susceptibility of isolates was investigated by the Kirby-Bauer and broth dilution techniques. Multidrug resistant species were tested for extended β-lactamase production potential. Results Inhabitants demonstrated adequate knowledge of waterborne diseases but employed inappropriate method (table salt) for well disinfection. Well construction and location violated guidelines. Indicator bacterial counts greatly exceeded the WHO guidelines. Variation in bacteriologic parameters between sites was not significant (P > 0.05) since well characteristics and hygiene and sanitary practices were similar. Differences in bacteriologic quality with respect to state of well, and presence of molded casing and lid, and height of casing were not significant (P > 0

  18. The Relationship Between Local Recurrence and Radiotherapy Treatment Volume for Soft Tissue Sarcomas Treated With External Beam Radiotherapy and Function Preservation Surgery

    SciTech Connect

    Dickie, Colleen I.; Griffin, Anthony M.; Parent, Amy L.; Chung, Peter W.M.; Catton, Charles N.; Svensson, Jon; Ferguson, Peter C.; Wunder, Jay S.; Bell, Robert S.; Sharpe, Michael B.; O'Sullivan, Brian

    2012-03-15

    Purpose: To examine the geometric relationship between local recurrence (LR) and external beam radiotherapy (RT) volumes for soft-tissue sarcoma (STS) patients treated with function-preserving surgery and RT. Methods and Materials: Sixty of 768 (7.8%) STS patients treated with combined therapy within our institution from 1990 through 2006 developed an LR. Thirty-two received preoperative RT, 16 postoperative RT, and 12 preoperative RT plus a postoperative boost. Treatment records, RT simulation images, and diagnostic MRI/CT data sets of the original and LR disease were retrospectively compared. For LR location analysis, three RT target volumes were defined according to the International Commission on Radiation Units and Measurements 29 as follows: (1) the gross tumor or operative bed; (2) the treatment volume (TV) extending 5 cm longitudinally beyond the tumor or operative bed unless protected by intact barriers to spread and at least 1-2 cm axially (the TV was enclosed by the isodose curve representing the prescribed target absorbed dose [TAD] and accounted for target/patient setup uncertainty and beam characteristics), and (3) the irradiated volume (IRV) that received at least 50% of the TAD, including the TV. LRs were categorized as developing in field within the TV, marginal (on the edge of the IRV), and out of field (occurring outside of the IRV). Results: Forty-nine tumors relapsed in field (6.4% overall). Nine were out of field (1.1% overall), and 2 were marginal (0.3% overall). Conclusions: The majority of STS tumors recur in field, indicating that the incidence of LR may be affected more by differences in biologic and molecular characteristics rather than aberrations in RT dose or target volume coverage. In contrast, only two patients relapsed at the IRV boundary, suggesting that the risk of a marginal relapse is low when the TV is appropriately defined. These data support the accurate delivery of optimal RT volumes in the most precise way using advanced

  19. Assessment of the effect of anthropometric data on the alterations of cardiovascular parameters in Lithuanian elite male basketball players during physical load.

    PubMed

    Žumbakytė-Šermukšnienė, Renata; Kajėnienė, Alma; Berškienė, Kristina; Daunoravičienė, Algė; Sederevičiūtė-Kandratavičienė, Rasa

    2012-01-01

    OBJECTIVES. The aim of the study was to assess the effect of the anthropometric data of basketball players on the alterations of cardiovascular parameters during the physical load applying the model of integrated evaluation. MATERIAL AND METHODS. The research sample consisted of 113 healthy Caucasian male basketball players, candidates of the Lithuanian National men's basketball teams. Basketball players were divided into 2 groups: 69 taller and heavier male basketball players (with a higher percentage of body fat) (TMB) and 44 shorter and less heavy male basketball players (with a lower percentage of body fat) (SMB). The amount of fat, expressed in percentage, was measured using the body composition analyzer TBF-300. "Kaunas-Load," a computerized ECG analysis system, was used to evaluate the functional condition of the cardiovascular system during the load. RESULTS. The TMB group had a lower heart rate during the warming-up phase and the steady state of the load as compared with the SMB group (P<0.05). The JT interval in the TMB group was greater during the warming-up and the steady state as compared with the SMB group (P<0.05). The JT/RR ratio index in the TMB group was found to be lower in the warming-up phase and in the steady state compared with the respective parameter in the SMB group (P<0.05). CONCLUSIONS. The cardiovascular system of taller and heavier male basketball players with a greater relative amount of body fat functioned more economically.

  20. Functional relationship between CABIT, SAM and 14-3-3 binding domains of GAREM1 that play a role in its subcellular localization

    SciTech Connect

    Nishino, Tasuku; Matsunaga, Ryota; Konishi, Hiroaki

    2015-08-21

    GAREM1 (Grb2-associated regulator of Erk/MAPK1) is an adaptor protein that is involved in the epidermal growth factor (EGF) pathway. The nuclear localization of GAREM1 depends on the nuclear localization sequence (NLS), which is located at the N-terminal CABIT (cysteine-containing, all in Themis) domain. Here, we identified 14-3-3ε as a GAREM-binding protein, and its binding site is closely located to the NLS. This 14-3-3 binding site was of the atypical type and independent of GAREM phosphorylation. Moreover, the binding of 14-3-3 had an effect on the nuclear localization of GAREM1. Unexpectedly, we observed that the CABIT domain had intramolecular association with the C-terminal SAM (sterile alpha motif) domain. This association might be inhibited by binding of 14-3-3 at the CABIT domain. Our results demonstrate that the mechanism underlying the nuclear localization of GAREM1 depends on its NLS in the CABIT domain, which is controlled by the binding of 14-3-3 and the C-terminal SAM domain. We suggest that the interplay between 14-3-3, SAM domain and CABIT domain might be responsible for the distribution of GAREM1 in mammalian cells. - Highlights: • 14-3-3ε regulated the nuclear localization of GAREM1 as its binding partner. • The atypical 14-3-3 binding site of GAREM1 is located near the NLS in CABIT domain. • The CABIT domain had intramolecular association with the SAM domain in GAREM1. • Subcellular localization of GAREM1 is affected with its CABIT-SAM interaction.

  1. Trend in eating habits among Lithuanian school-aged children in context of social inequality: three cross-sectional surveys 2002, 2006 and 2010

    PubMed Central

    2012-01-01

    Background Intermittent monitoring of food intake at the population level is essential for the planning and evaluation of national dietary intervention programs. Social-economic changes in Lithuania have likely affected dietary habits, but only a limited number of temporal studies on food intake trends among young population groups have been published. The aim of this study was to investigate changes in eating habits among Lithuanian school-aged children from 2002 to 2010, and to explore the association of these changes with the respondents' reported socio-economic status (SES). Methods We used Lithuanian data from the cross-national Health Behaviour in School-aged Children (HBSC) study collected in 2002, 2006 and 2010. Analyses were conducted on comparable questionnaire-based data from children aged 11, 13 and 15 (total n = 17,189) from a random sample of schools. A food frequency questionnaire was used to investigate frequencies of food consumption. Logistic regression was used to examine the affects of changing social variables on reported diet trends. Results In Lithuania, school-aged children have low intakes of fruits and vegetables. Only 21.1% of boys and 27.1% of girls reported daily fruit consumption. Similarly, 24.9% of boys and 29.6% of girls disclosed vegetable intake at least once daily. Comparing 2010 to 2002, the proportion of girls who consumed fruits daily increased from 24.2% to 31.0% (p < 0.001) but the proportion of boys who consumed vegetables daily decreased from 29.3% to 23.1% (p < 0.001). In 2006, for both sexes, there were observed increases in regular (at least five days a week) intake of sweets and chocolates, biscuits and pastries, and soft drinks; however, in the next survey (2010) these figures decreased. In addition, between 2006 and 2010, a substantial decrease in regular consumption of chips and fast food was also detected. Fruit and vegetable consumption as well as intake of sweets and chocolates, biscuits and pastries and soft

  2. Link between healthy lifestyle and psychological well-being in Lithuanian adults aged 45–72: a cross-sectional study

    PubMed Central

    Sapranaviciute-Zabazlajeva, Laura; Luksiene, Dalia; Virviciute, Dalia; Bobak, Martin; Tamosiunas, Abdonas

    2017-01-01

    Objective This study uses a cross-sectional study design to analyse the connection between psychological well-being (PWB) and components of a healthy lifestyle in the Lithuanian population aged 45–72. The purpose of our study is to establish the links between PWB and lifestyle factors such as physical activity, smoking, alcohol consumption and dietary patterns in people above the age of 44. Participants A stratified sample of 10 940 urban citizens aged 45–72 years were randomly selected from the National Population Register. The response rate was 65%. Methods PWB was evaluated by using a Control Autonomy Self-realization and Pleasure (CASP-12) questionnaire. The standard questionnaire included questions regarding the respondent's sociodemographic, socioeconomic and social status. The lifestyle questionnaire evaluated behavioural factors as smoking status, alcohol consumption, nutrition habits and physical activity. Objective measurements of cardiovascular disease (CVD) risk factors were taken. Results Adjusted for sociodemographic, socioeconomic, social and biological CVD risk factors, the probability of higher PWB increased for physically active men and women and male former smokers. Higher PWB was directly associated with consumption of fresh vegetables and fruits. Responders who consumed potatoes, meat, boiled vegetables and eggs less frequently than average were more likely to have higher PWB. A direct association was ascertained between PWB and consumption of chicken and fish, as well as an inverse association between PWB and consumption of sweets in women. Conclusions Healthy lifestyle education efforts should focus on increasing physical activity, controlling smoking and improving diversity in healthy food consumption including the consumption of fresh vegetables and fruits, particularly among older adults with lower PWB. PMID:28373254

  3. The Relationship between Local Wealth and Dual Enrollment Participation in Virginia's Community Colleges: Rural, Urban, and Suburban Patterns and Subsequent Postsecondary Enrollment Status

    ERIC Educational Resources Information Center

    Davenport, Ellen Richardson

    2013-01-01

    In Virginia, the availability of dual enrollment classes for high school students has varied, depending on the interest of the local school division and the community college's president in whose service region the school division is located. HB 1184, which passed in the 2012 session of the Virginia General Assembly, stipulates that the…

  4. Blaming the Government for Environmental Problems: A Multilevel and Cross-National Analysis of the Relationship between Trust in Government and Local and Global Environmental Concerns

    ERIC Educational Resources Information Center

    Cin, Cigdem Kentmen

    2013-01-01

    Although the determinants of trust in governments have received significant attention in the literature on political trust, there has been no attention paid to whether environmental concerns affect governmental trust. Yet, if individuals are worried about local and global environmental degradation, they may think that the government has failed in…

  5. Analyzing relationships between surface perturbations and local chemical reactivity of metal sites: Alkali promotion of O2 dissociation on Ag(111)

    NASA Astrophysics Data System (ADS)

    Xin, Hongliang; Linic, Suljo

    2016-06-01

    Many commercial heterogeneous catalysts are complex structures that contain metal active sites promoted by multiple additives. Developing fundamental understanding about the impact of these perturbations on the local surface reactivity is crucial for catalyst development and optimization. In this contribution, we develop a general framework for identifying underlying mechanisms that control the changes in the surface reactivity of a metal site (more specifically the adsorbate-surface interactions) upon a perturbation in the local environment. This framework allows us to interpret fairly complex interactions on metal surfaces in terms of specific, physically transparent contributions that can be evaluated independently of each other. We use Cs-promoted dissociation of O2 as an example to illustrate our approach. We concluded that the Cs adsorbate affects the outcome of the chemical reaction through a strong alkali-induced electric field interacting with the static dipole moment of the O2/Ag(111) system.

  6. Analyzing relationships between surface perturbations and local chemical reactivity of metal sites: Alkali promotion of O2 dissociation on Ag(111).

    PubMed

    Xin, Hongliang; Linic, Suljo

    2016-06-21

    Many commercial heterogeneous catalysts are complex structures that contain metal active sites promoted by multiple additives. Developing fundamental understanding about the impact of these perturbations on the local surface reactivity is crucial for catalyst development and optimization. In this contribution, we develop a general framework for identifying underlying mechanisms that control the changes in the surface reactivity of a metal site (more specifically the adsorbate-surface interactions) upon a perturbation in the local environment. This framework allows us to interpret fairly complex interactions on metal surfaces in terms of specific, physically transparent contributions that can be evaluated independently of each other. We use Cs-promoted dissociation of O2 as an example to illustrate our approach. We concluded that the Cs adsorbate affects the outcome of the chemical reaction through a strong alkali-induced electric field interacting with the static dipole moment of the O2/Ag(111) system.

  7. The relationship between local liquid density and force applied on a tip of atomic force microscope: A theoretical analysis for simple liquids

    SciTech Connect

    Amano, Ken-ichi Takahashi, Ohgi; Suzuki, Kazuhiro; Fukuma, Takeshi; Onishi, Hiroshi

    2013-12-14

    The density of a liquid is not uniform when placed on a solid. The structured liquid pushes or pulls a probe employed in atomic force microscopy, as demonstrated in a number of experimental studies. In the present study, the relation between the force on a probe and the local density of a liquid is derived based on the statistical mechanics of simple liquids. When the probe is identical to a solvent molecule, the strength of the force is shown to be proportional to the vertical gradient of ln(ρ{sub DS}) with the local liquid's density on a solid surface being ρ{sub DS}. The intrinsic liquid's density on a solid is numerically calculated and compared with the density reconstructed from the force on a probe that is identical or not identical to the solvent molecule.

  8. The creation of new traditions: Discussion of relationship between architectural rural practice and local features' inheriting from a heritage conservation perspective

    NASA Astrophysics Data System (ADS)

    Tian, M.; Sun, M.

    2015-08-01

    The traditional features of Chinese villages are facing a crisis of discontinuity. In the meantime, there exists a problem in architectural heritage conservation that while preservation and renovation is being done, local self-help construction still proceeds out of control. Nowadays, an increasing number of architects have noticed these phenomena and participate in the evolution of villages carrying various architectural practices in the countryside, which has certain influence at the place, whether during or after the construction. In many well-evaluated rural practice cases in the world, architects not only choose appropriate materials and crafts for natives, but also renew local traditions by offering skill training to craftsmen. However, in Chinese villages, similar practices do not seem to be that effective. Therefore, through field research and interviews, this article discusses the reasons that relatively successful architectural practices in Chinese villages fail to exert a positive influence to the inheriting and update of local traditions. These causes include the increase of information sources, the different aesthetic manner, the conception differences, the influence of constructors, and the instructor role that architects play.

  9. Time-dose relationships for local tumor control and complications following irradiation of squamous cell carcinoma of the base of tongue

    SciTech Connect

    Gardner, K.E.; Parsons, J.T.; Mendenhall, W.M.; Million, R.R.; Cassisi, N.J.

    1987-04-01

    Between October 1964 and September 1981, 114 previously untreated patients with squamous cell carcinoma of the base of the tongue were treated with curative intent by a radical course of irradiation at the University of Florida. With a minimum 2-year follow-up, local control was achieved in 78, 65, 76, and 17% of T1, T2, T3, and T4 lesions, respectively. Control results could be correlated with time-dose factors and treatment techniques. No patient required mandibulectomy for osteoradionecrosis following radiation therapy. Complications of bone and soft tissue could not be related to time-dose factors.

  10. Interaural Coherence and Localization

    NASA Astrophysics Data System (ADS)

    Pepin, Eric

    2006-10-01

    In a study of the relationship between interaural coherence and localization ability, two experiments were performed. Both made use of a 1/3 octave band of low frequency sound and a 1/3 octave band of high frequency sound. Stimuli with coherences ranging from 0.2 to 0.8 were created in three recording environments using a KEMAR and digitally altered to eliminate interaural level differences (ILD). The environments had short, medium, and long reverberation times. The coherences were measured and were accurate to one significant figure. Experiment 1 had two goals: to determine the relationship between interaural coherence and the ability to localize using interaural time differences (ITD) and to determine if localization ability was dependent only on coherence. The relationship between coherence and localization was tested in a headphone lateralization experiment in which psychometric functions were generated. The functions revealed a linear relationship, with the ability to localize high coherence sounds breaking down quickly at small ITD. Within standard error, ITD localization appeared to be dependent only on coherence. In Experiment 2, a 3-down 1-up staircase method was employed to determine how opposing ILDs affected ITD localization. When the task could be completed, the threshold values were linearly related, however, the ability broke down at large ILDs. Both experiments provide a linear description of interaural coherence and localization, with thresholds being sharp deviations from these trends.

  11. Periodicities in mid- to late-Holocene peatland hydrology identified from Swedish and Lithuanian tree-ring data

    NASA Astrophysics Data System (ADS)

    Edvardsson, Johannes; Adolphi, Florian; Linderholm, Hans W.; Corona, Christophe; Muscheler, Raimund; Stoffel, Markus

    2016-04-01

    Twenty-five tree-ring width (TRW) chronologies, developed from moisture sensitive peatland trees in Sweden and Lithuania, and representing eight periods during the mid-Holocene to present, were analysed regarding common periodicities (cycles). Periods of 13-15, 20-22, and 30-35 years were found in most chronologies, while 8-10, 18-19, and 60-65 year periodicities were observed as well, but less commonly. Similar periodicities, especially about 15 and 30 years in duration, were detected in both living and subfossil trees, indicating that the trees have responded to similar forcing mechanisms on those timescales through time. Some of the detected periods may be related to solar variability and lunar nodal tides, but most of the detected periodicities are more likely linked to hydrological changes in the peatlands associated to atmospheric patterns such as the North Atlantic Oscillation (NAO), or variations in sea surface temperatures (i.e. the Atlantic Multidecadal Oscillation, AMO). However, no significant relationships between tree growth, NAO and AMO could be formally established, possibly due to hydrological lag and feedback effects which are typical for peatlands but render in-depth assessments rather difficult.

  12. A Bootstrap Technique for Testing the Relationship Between Local-Scale Radar Observations of Cloud Occurrence and Large-Scale Atmospheric Fields

    SciTech Connect

    Marchand, Roger T.; Beagley, Nathaniel; Thompson, Sandra E.; Ackerman, Thomas P.; Schultz, David M.

    2006-11-01

    In this paper an atmospheric classification scheme based on fields that are resolved by global climate models (and numerical weather prediction models) is investigated as a mechanism to map the large-scale (synoptic-scale) atmospheric state to distributions of local-scale cloud properties. Using a bootstrap resampling technique, the temporal stability and distinctness of vertical profiles of cloud occurrence (obtained from a vertically pointing millimeter wavelength cloud-radar) are analyzed as a function of the atmospheric state. A stable class-based map from the large-scale to local-scale cloud properties could be of great utility in the analysis of GCM-predicted cloud properties, by providing a physical context from which to understand any differences between the model output and observations, as well as to separate differences (in total distribution) that are caused by having different weather regimes (or synoptic scale activity) rather than problems in the representation of clouds for a particular regime. Furthermore, if sufficiently robust mappings can be established, it could form the basis of a statistical GCM cloud parameterization.

  13. From local force-flux relationships to internal dissipations and their impact on heat engine performance: the illustrative case of a thermoelectric generator.

    PubMed

    Apertet, Y; Ouerdane, H; Goupil, C; Lecoeur, Ph

    2013-08-01

    We present an in-depth analysis of the sometimes understated role of the principle of energy conservation in linear irreversible thermodynamics. Our case study is that of a thermoelectric generator (TEG), which is a heat engine of choice in irreversible thermodynamics, owing to the coupling between the electrical and heat fluxes. We show why Onsager's reciprocal relations must be considered locally and how internal dissipative processes emerge from the extension of these relations to a global scale: The linear behavior of a heat engine at the local scale is associated with a dissipation process that must partake in the global energy balance. We discuss the consequences of internal dissipations on the so-called efficiency at maximum power, in the light of our comparative analyses of exoreversibility and endoreversibility on the one hand and of two classes of heat engines, autonomous and periodically driven, on the other hand. Finally, basing our analysis on energy conservation, we also discuss recent works which claim the possibility to overcome the traditional boundaries on efficiency imposed by finite-time thermodynamics in thermoelectric systems with broken time-reversal symmetry; this we do by introducing a "thermal" thermopower and an "electrical" thermopower which permits an analysis of the thermoelectric response of the TEG considering a possible dissymmetry between the electrical/thermal and the thermal/electrical couplings.

  14. Ecotoxicological study of Lithuanian and Estonian wastewaters: selection of the biotests, and correspondence between toxicity and chemical-based indices.

    PubMed

    Manusadzianas, L; Balkelyte, L; Sadauskas, K; Blinova, I; Põllumaa, L; Kahru, A

    2003-03-17

    The toxicity of industrial and urban wastewater (WW) samples collected in Lithuania and Estonia was evaluated by using a suite of biological tests comprising the Algaltoxkit F with Selenastrum capricornutum, the Charatox with Nitellopsis obtusa, Daphtoxkit F with Daphnia magna, Thamnotoxkit F with Thamnocephalus platyurus, Protoxkit F with Tetrahymena thermophila and the Microtox with Vibrio fischeri. The Charatox and Thamnotoxkit F tests showed highest relative sensitivity, responding to 80-90% of samples, respectively, and both expressed good discrimination capacity between samples. Principal Component and pairwise correlation analysis allowed to select test-battery consisting of Charatox, Thamnotoxkit and Microtox. The WW toxicity was evaluated by means of cumulative indices such as average toxicity (AvTx) and two indices derived from the PEEP-index (Environ. Toxicol. Water Qual. 8 (1993) 115). In addition to these integrated evaluations of test-battery response, WW toxicity was evaluated according to the most sensitive test (MST) in the battery. The linear regression analysis between cumulative toxicity indices and chemical-based indices (derived from comparison of WW chemical concentrations and their respective maximum allowable concentration) revealed positive linear relationships (r(2)=0.7-0.8), while toxicity evaluation based on the MST was less positively related with chemical analysis data (r(2)=0.5-0.6). Although better coincidence between the toxicity and chemical-based assessments was achieved when information from all tests in the battery was assembled, the prediction of toxicity from chemical data was still limited. In search of suitable test-battery for the screening of certain type of WWs, a preliminary study comprising excessive suite of tests might be useful.

  15. Antioxidant state and mortality from coronary heart disease in Lithuanian and Swedish men: concomitant cross sectional study of men aged 50.

    PubMed Central

    Kristenson, M.; Ziedén, B.; Kucinskienë, Z.; Elinder, L. S.; Bergdahl, B.; Elwing, B.; Abaravicius, A.; Razinkovienë, L.; Calkauskas, H.; Olsson, A. G.

    1997-01-01

    OBJECTIVE: To investigate possible risk factors and mechanisms behind the four times higher and diverging mortality from coronary heart disease in Lithuanian compared with Swedish middle aged men. DESIGN: Concomitant cross sectional comparison of randomly selected 50 year old men without serious acute or chronic disease. Methods and equipment were identical or highly standardised between the centres. SETTING: Linköping (Sweden) and Vilnius (Lithuania). SUBJECTS: 101 and 109 men aged 50 in Linköping and Vilnius respectively. MAIN OUTCOME MEASURES: Anthropometric data, blood pressure, smoking, plasma lipid and lipoprotein concentrations, susceptibility of low density lipoprotein to oxidation, and plasma concentrations of fat soluble antioxidant vitamins. RESULTS: Systolic blood pressure was higher (141 v 133 mm Hg, P < 0.01), smoking habits were similar, and plasma total cholesterol (5.10 v 5.49 mmol/l, P < 0.01) and low density lipoprotein cholesterol (3.30 v 3.68 mmol/l, P < 0.01) lower in men from Vilnius compared with those from Linköping. Triglyceride, high density lipoprotein cholesterol, and Lp(a) lipoprotein concentrations did not differ between the two groups. The resistance of low density lipoprotein to oxidation was lower in the men from Vilnius; lag phase was 67.6 v 79.5 minutes (P < 0.001). Also lower in the men from Vilnius were mean plasma concentrations of lipid soluble antioxidant vitamins (beta carotene 377 v 510 nmol/l, P < 0.01; lycopene 327 v 615 nmol/l, P < 0.001; and lipid adjusted gamma tocopherol 0.25 v 0.46 mumol/mmol, P < 0.001. alpha Tocopherol concentration did not differ). Regression analysis showed that the lag phase was still significantly shorter by 10 minutes in men from Vilnius when the influence of other known factors was taken into account. CONCLUSIONS: The high mortality from coronary heart disease in Lithuania is not caused by traditional risk factors alone. Mechanisms related to antioxidant state may be important. PMID

  16. Ocean-atmosphere relationships from synoptic scale to local scale in South San Francisco Bay, with implications to flood risk at NASA Ames Research Center, Silicon Valley

    NASA Astrophysics Data System (ADS)

    Mills, W. B.; Costa-Cabral, M. C.; Bromirski, P. D.; Miller, N. L.; Coats, R. N.; Loewenstein, M.; Roy, S. B.; MacWilliams, M.

    2012-12-01

    This work evaluates the implications to flooding risk at the low-lying NASA Ames Research Center in South San Francisco Bay under historical and projected climate and sea level rise. Atmospheric circulation patterns over the Pacific Ocean, influenced by ENSO and PDO, can result in extended periods of higher mean coastal sea level in California. Simultaneously they originate a larger number of storms that make landfall and have higher mean intensity. These storms generate barometrically-induced high water anomalies, and winds that are sometimes capable of producing large coastal waves. Storm surges that propagate from the coast into the estuary and South Bay, and locally-generated waves, may compromise the discharge capacity of stream channels. These conditions also typically generate high intensity rainfall, and the reduced channel capacity may result in fluvial flooding. Such atmospheric circulation patterns may persist for many months, during which California experiences more precipitation events of longer mean duration and higher intensity, leading to large precipitation totals that saturate soils and may exceed the storage capacity of stormwater retention ponds. Future scenarios of sea level rise, that may surpass a meter in this century according to the projections recently published by the National Research Council for states of CA, OR and WA, and projected atmospheric circulation changes associated with anthropogenic climate change, may amplify these risks. We evaluate the impacts of these changes on NASA's Ames Research Center through four areas of study: (i) wetland accretion and evolution as mean sea level rises, with implications to the Bay's response to the sea level rise and storm surges, (ii) hydrodynamic modeling to simulate the propagation of tidal height and storm surges in the Bay and the influence of local winds on wave height, (iii) evaluation of historical data and future climate projections to identify extreme precipitation events, and (iv

  17. Detailed Relationship Between Local Structure Polarons and Magnetization for La1-xCaxMnO3 (0.21 lt x lt 0.45)

    SciTech Connect

    F Bridges; L Downward; J Neumeier; T Tyson

    2011-12-31

    We present detailed local structure measurements (using the extended x-ray absorption fine structure technique) for the colossal magnetoresistive material La{sub 1-x}Ca{sub x}MnO{sub 3} (0.21 < x < 0.45) as a function of temperature and magnetic field. The local distortions of the Mn-O bonds are parameterized using {sigma}, the width of the Mn-O pair-distribution function (PDF). After subtracting thermal phonon contributions, we show that the contributions to {sigma}{sup 2} from polaron and Jahn-Teller (JT) distortions, {sigma}{sub JT/polaron}{sup 2}, are a universal function of the magnetization, independent of how the magnetization is achieved via changes in temperature or magnetic field. However this universal behavior is only observed for B fields {ge} 2 T, likely as a result of domain canting in low B fields. The resulting curve is well described by two straight lines with significantly different slopes. These regimes represent two distinctly differ distortions of the oxygen octahedra about the Mn. For low magnetizations up to {approx}65% of the theoretical maximum magnetization, M{sub T}, the slope is low and the distortion removed as the sample becomes magnetized is small - we argue this arises from polarons which have a low distortion around two (or possibly three) Mn sites. At high magnetizations large distortions per Mn site are removed as these sites become magnetized. The data are also analyzed in terms of a two Mn-O peak distribution using experimental standards for Mn-O. The results agree well with recent neutron PDF results but not with some earlier results. We discuss the limitations of assuming a two peak distribution in view of the two distortions needed to describe the Mn-O distortions as a function of T and B for B {ge} 2 T. It is likely that there is a distribution of longer bonds. Finally we show that with increasing B field, the Mn-Mn peak also has a small B-field-induced change - a measure at the unit cell level of magnetostriction but find

  18. Can parasites be indicators of free-living diversity? Relationships between species richness and the abundance of larval trematodes and of local benthos and fishes

    USGS Publications Warehouse

    Hechinger, R.F.; Lafferty, K.D.; Huspeni, T.C.; Brooks, A.J.; Kuris, A.M.

    2007-01-01

    Measuring biodiversity is difficult. This has led to efforts to seek taxa whose species richness correlates with the species richness of other taxa. Such indicator taxa could then reduce the time and cost of assessing the biodiversity of the more extensive community. The search for species richness correlations has yielded mixed results, however. This may be primarily because of the lack of functional relationships between the taxa studied. Trematode parasites are highly promising bioindicators. Diverse assemblages of larval trematode parasites are easily sampled in intermediate host snails. Through their life cycles these parasites are functionally coupled with the surrounding free-living diversity of vertebrate and invertebrate animals. It has been shown that larval trematodes in snails correlate positively with bird diversity and abundance. Here, we explore whether trematodes also correlate with standard measures of fishes, and large and small benthos, for 32 sites in three wetlands. We found associations between trematodes and benthic communities that were not consistent across wetlands. The associations were, however, consistently positive for large benthic species richness and density. Some of the contrasting associations between trematode and benthos may be explained by negative associations between large and small benthos. We found no associations with fish communities (probably because of the inadequacy of standard "snapshot" sampling methods for highly mobile fishes). The results support further exploration of trematodes as bioindicators of diversity and abundance of animal communities. ?? 2006 Springer-Verlag.

  19. Can parasites be indicators of free-living diversity? Relationships between species richness and the abundance of larval trematodes and of local benthos and fishes.

    PubMed

    Hechinger, Ryan F; Lafferty, Kevin D; Huspeni, Todd C; Brooks, Andrew J; Kuris, Armand M

    2007-02-01

    Measuring biodiversity is difficult. This has led to efforts to seek taxa whose species richness correlates with the species richness of other taxa. Such indicator taxa could then reduce the time and cost of assessing the biodiversity of the more extensive community. The search for species richness correlations has yielded mixed results, however. This may be primarily because of the lack of functional relationships between the taxa studied. Trematode parasites are highly promising bioindicators. Diverse assemblages of larval trematode parasites are easily sampled in intermediate host snails. Through their life cycles these parasites are functionally coupled with the surrounding free-living diversity of vertebrate and invertebrate animals. It has been shown that larval trematodes in snails correlate positively with bird diversity and abundance. Here, we explore whether trematodes also correlate with standard measures of fishes, and large and small benthos, for 32 sites in three wetlands. We found associations between trematodes and benthic communities that were not consistent across wetlands. The associations were, however, consistently positive for large benthic species richness and density. Some of the contrasting associations between trematode and benthos may be explained by negative associations between large and small benthos. We found no associations with fish communities (probably because of the inadequacy of standard "snapshot" sampling methods for highly mobile fishes). The results support further exploration of trematodes as bioindicators of diversity and abundance of animal communities.

  20. Flow-force relationships in lettuce thylakoids. 2. Effect of the uncoupler FCCP on local proton resistances at the ATPase level.

    PubMed

    Sigalat, C; de Kouchkovsky, Y; Haraux, F

    1993-09-28

    The relationship between the steady-state proton gradient (delta pH) and the rate of phosphorylation was investigated in thylakoids under various conditions. Under partial uncoupling by carbonyl cyanide p-(trifluoromethoxy)phenylhydrazone (FCCP), the rate of ATP synthesis was reduced by less than expected from the decrease of delta pH. This was observed in the case of the pyocyanine-mediated cyclic electron flow around photosystem 1, but not with the H2O-->photosystem 2-->cytochrome b6f-->photosystem 1-->methyl viologen system. In state 4, a unique relation was found between delta pH and the "phosphate potential", delta Gp, regardless of whether the energy level was controlled by light input or FCCP. The anomalous effect of FCCP on the rate of ATP synthesis disappeared when the ATPase was partially blocked by the reversible inhibitor venturicidin, but not in the presence of tentoxin, an irreversible inhibitor. These results are consistent with the existence of a small kinetic barrier for protons, limiting their access to the ATPase. This resistance would be collapsed by FCCP.

  1. Novel serine-based gemini surfactants as chemical permeation enhancers of local anesthetics: A comprehensive study on structure-activity relationships, molecular dynamics and dermal delivery.

    PubMed

    Teixeira, Raquel S; Cova, Tânia F G G; Silva, Sérgio M C; Oliveira, Rita; do Vale, M Luísa C; Marques, Eduardo F; Pais, Alberto A C C; Veiga, Francisco J B

    2015-06-01

    This work aims at studying the efficacy of a series of novel biocompatible, serine-based surfactants as chemical permeation enhancers for two different local anesthetics, tetracaine and ropivacaine, combining an experimental and computational approach. The surfactants consist of gemini molecules structurally related, but with variations in headgroup charge (nonionic vs. cationic) and in the hydrocarbon chain lengths (main and spacer chains). In vitro permeation and molecular dynamics studies combined with cytotoxicity profiles were performed to investigate the permeation of both drugs, probe skin integrity, and rationalize the interactions at molecular level. Results show that these enhancers do not have significant deleterious effects on the skin structure and do not cause relevant changes on cell viability. Permeation across the skin is clearly improved using some of the selected serine-based gemini surfactants, namely the cationic ones with long alkyl chains and shorter spacer. This is noteworthy in the case of ropivacaine hydrochloride, which is not easily administered through the stratum corneum. Molecular dynamics results provide a mechanistic view of the surfactant action on lipid membranes that essentially corroborate the experimental observations. Overall, this study suggests the viability of these serine-based surfactants as suitable and promising delivery agents in pharmaceutical formulations.

  2. Human cytomegalovirus and mucoepidermoid carcinoma of salivary glands: cell-specific localization of active viral and oncogenic signaling proteins is confirmatory of a causal relationship.

    PubMed

    Melnick, Michael; Sedghizadeh, Parish P; Allen, Carl M; Jaskoll, Tina

    2012-02-01

    Human cytomegalovirus (hCMV) infection is common. Although still controversial, there is growing evidence that active hCMV infection is associated with a variety of malignancies, including brain, breast, lung, colon, and prostate. Given that hCMV is frequently resident in salivary gland (SG) ductal epithelium, we hypothesized that hCMV would be important to the pathogenesis of SG mucoepidermoid carcinoma (MEC). This was initially supported by our finding that purified CMV induces malignant transformation in SG cells in an in vitro mouse model, and utilizes a pathogenic pathway previously reported for human MEC. Here we present the histologic and molecular characterizations of 39 human SG MECs selected randomly from a repository of cases spanning 2004-2011. Serial sections were obtained from formalin-fixed, paraffin embedded, tissue blocks from previous incisional or excisional biopsies. Immunohistochemical assays were performed for active hCMV proteins (IE1 and pp65) and the activated COX/AREG/EGFR/ERK signaling pathway. All four prospective causal criteria for viruses and cancer are fully satisfied: (1) protein markers for active hCMV are present in 97% of MECs; (2) markers of active hCMV are absent in non-neoplastic SG tissues; (3) hCMV-specific proteins (IE1, pp65) are in specific cell types and expression is positively correlated with severity; (4) hCMV correlates and colocalizes with an upregulation and activation of an established oncogenic signaling pathway (COX/AREG/EGFR/ERK). Thus, the evidential support reported here and previously in a mouse model is strongly confirmatory of a causal relationship between hCMV and SG mucoepidermoid carcinoma. To our knowledge, this is the first demonstration of hCMV's role in human oncogenesis that fully responds to all of Koch's Postulates as revised for viruses and cancer. In the absence of any contrary evidence, hCMV can reasonably be designated an "oncovirus."

  3. The Bacterial Composition within the Sarracenia purpurea Model System: Local Scale Differences and the Relationship with the Other Members of the Food Web

    PubMed Central

    Gray, Sarah M.; Akob, Denise M.; Green, Stefan J.; Kostka, Joel E.

    2012-01-01

    The leaves of the carnivorous pitcher plant, Sarracenia purpurea, contain a microscopic aquatic food web that is considered a model system in ecological research. The species identity of the intermediate and top trophic level of this food web, as well the detritivore midge, are highly similar across the native geographic range of S. purpurea and, in some cases, appear to have co-evolved with the plant. However, until recently, the identity, geographic variation, and diversity of the bacteria in the bottom trophic level of this food web have remained largely unknown. This study investigated bacterial community composition inside the leaves of S. purpurea to address: 1) variation in bacterial communities at the beginning of succession at the local scale in different areas of the plant’s native geographic range (southern and mid-regional sites) and 2) the impacts of bacterial consumers and other members of the aquatic food web (i.e., insects) on bacterial community structure. Communities from six leaves (one leaf per plant) from New York and Florida study sites were analyzed using 16S ribosomal RNA gene cloning. Each pitcher within each site had a distinct community; however, there was more overlap in bacterial composition within each site than when communities were compared across sites. In contrast, the identity of protozoans and metazoans in this community were similar in species identity both within a site and between the two sites, but abundances differed. Our results indicate that, at least during the beginning of succession, there is no strong selection for bacterial taxa and that there is no core group of bacteria required by the plant to start the decomposition of trapped insects. Co-evolution between the plant and bacteria appears to not have occurred as it has for other members of this community. PMID:23227224

  4. Local tumor control following single dose irradiation of human melanoma xenografts: Relationship to cellular radiosensitivity and influence of an immune response by the athymic mouse

    SciTech Connect

    Rofstad, E.K.

    1989-06-15

    The potential usefulness of untreated congenitally athymic adult mice as hosts for human tumors in radiocurability studies was investigated using five human melanoma xenograft lines (E.E., E.F., G.E., M.F., V.N.). The tumor radiocurability was found to differ considerably among the lines; the radiation doses required to achieve local control of 50% of the tumors irradiated (TCD50 values) ranged from 29.6 +/- 2.1 (SE) to 67.9 +/- 3.5 Gy. Since the clinical relevance of experimentally determined TCD50 values depends on to what extent they are modified by a host immune response, a possible immune reactivity against the melanomas was investigated by comparing the radiocurability data with cell survival data measured in vitro after irradiation in vivo and by performing quantitative tumor transplantability studies. The radiocurability and the cell survival data were found to agree well for the E.F., G.E., and M.F. melanomas. Moreover, the number of tumor cells required to achieve tumors in 50% of the inoculation sites (TD50 values) in untreated and in whole-body irradiated mice were similar, suggesting that the TCD50 values measured for these lines were not significantly influenced by a host immune response. On the other hand, the E.E. and V.N. melanomas showed significantly lower TCD50 values in vivo than predicted theoretically from the in vitro cell survival data and a significantly lower number of tumor cells required to achieve tumors in 50% of the inoculation sites in whole-body irradiated than in untreated mice, suggesting that the radiocurability of these two lines was enhanced due to an immune response by the host. Athymic mice may thus express a significant immune reactivity against some human tumor xenograft lines but not against others.

  5. Seasonal studies on commensal rats and their ectoparasites in a rural area of Egypt: the relationship of ectoparasites to the species, locality, and relative abundance of the host.

    PubMed

    Soliman, S; Main, A J; Marzouk, A S; Montasser, A A

    2001-06-01

    The present study was carried out in 3 villages, namely Kafr Ayoub Soliman, Kafr Ibrahim El-Aidi, and El-Sa'adat, Sharqiya Governorate, Egypt. A total of 519 rats was collected from the 3 study sites: 46.6% Rattus rattus, and 53.4% Rattus norvegicus. A total of 20,643 ectoparasites was recovered from R. rattus: 33.3% mites, 33.8% fleas, and 32.9% lice. From R. norvegicus a total of 40,997 ectoparasites was recovered: 28.9% mites, 31% fleas, and 40.1% lice. Three common mite species were recovered from both rat hosts, i.e., Ornithonyssus bacoti, Radfordia ensifera, and Laelaps nuttalli. Three common flea species were also recovered from both rat hosts, i.e., Echidnophaga gallinacea, Leptopsylla segnis, and Xenopsylla cheopis. Polyplax spinulosa was the only dominant louse species that infested both rat hosts. Rats did not show a definite breeding season, and the seasonal rat indices were generally low in different study sites. There were no significant differences between the prevalence of each of mites, fleas, and lice in both rat species. The total general indices of mites and fleas, on the other hand, was significantly higher in R. norvegicus. The general index of X. cheopis was high and ranged between 5.9 in R. rattus and 14.5 in R. norvegicus. Season-related changes were observed in the general index of each of L. segnis infesting both rat species and R. ensifera and O. bacoti infesting R. norvegicus. The prevalence and general indices of some ectoparasites showed differences related to the locality of their rat hosts. Seasonal changes in the general indices of some ectoparasites paralleled seasonal changes in the relative abundance of their rat hosts.

  6. Building Relationships with Reporters

    ERIC Educational Resources Information Center

    Kidwai, Sabrina

    2008-01-01

    Each story that is written about career and technical education (CTE) increases knowledge and support with local government, school officials and the community. The first step in improving publicity for one's program is to build a relationship with local reporters covering education. In this article, the author discusses how important it is to…

  7. Spatial Relationships Between Bacteria and Localized Corrosion,

    DTIC Science & Technology

    1996-03-01

    of corrosion products on specimens with crevices. After 11 days, 50 ml of natural seawater was added to the abiotic electrolytes containing electrodes...De Mele, H. A. Videla, "Interacciones de Biopeliculas Bacterianas y Compuestos Inorganicos Sobre Aceros Protegidos Catodicamente," 5th Congreso Ibero

  8. State and local governments

    NASA Technical Reports Server (NTRS)

    Barnes, Dennis

    1990-01-01

    The Virginia Space Grant Consortium approach to a close working relation to state and local governments is presented as a model for consideration. State government relations are especially important in that this is a primary resource in securing matching funds. Avenues for establishing these relationships are listed and discussed.

  9. Local gravitomagnetism

    NASA Astrophysics Data System (ADS)

    Shahid-Saless, Bahman

    1990-10-01

    In a simple two-body system, the gravitomagnetic components of the metric in the local quasi-inertial frame of one of the bodies is calculated. The local geometry in this frame which is freely falling along the geodesic but is directionally fixed with respect to distant stars is primarily defined by the gravitomagnetic components of the local metric. This metric serves to track down the various contributions from the local and distant source and thus provides further insight to the nature of gravitomagnetism. As a result it is shown that in the quasi-inertial frame geodetic precession is a gravitomagnetic phenomenon. Furthermore a connection between local gravitomagnetic effects and Einstein's principle of equivalence is established.

  10. Antimicrobial Resistance Profiles of Campylobacter spp. Isolated from Broiler Chicken Meat of Estonian, Latvian and Lithuanian Origin at Estonian Retail Level and from Patients with Severe Enteric Infections in Estonia.

    PubMed

    Mäesaar, M; Kramarenko, T; Meremäe, K; Sõgel, J; Lillenberg, M; Häkkinen, L; Ivanova, M; Kovalenko, K; Hörman, A; Hänninen, M-L; Roasto, M

    2016-03-01

    The resistance patterns of Campylobacter spp. isolated from retail broiler chicken meat originating either from Estonia, Lithuania or Latvia collected in Estonia were determined. Additionally, in collaboration with the laboratories of several Estonian hospitals, antimicrobial susceptibility patterns were determined for Campylobacter isolates from patients with severe Campylobacter enteric infections. The isolates were identified at the species level by the PCR method. Respectively, 88.8% of the isolates were C. jejuni, and 11.2% were C. coli. In total, 126 Campylobacter isolates of broiler chicken meat and human origin were tested for minimal inhibitory concentrations (MICs) with the broth microdilution VetMIC(TH) method (National Veterinary Institute; Uppsala, Sweden) for a total of six antimicrobials. Resistance to one or more antimicrobials was detected in 62 (63.3%) of Campylobacter broiler chicken meat isolates and in 20 (71.4%) of human-origin isolates. Large proportions of the broiler chicken meat isolates were resistant to ciprofloxacin (60.2%). Multidrug resistance (i.e. to three or more unrelated antimicrobials) was detected in five (5.1%) C. jejuni isolates. Among the human isolates, 20 (71.4%) were resistant to fluoroquinolones, and two (7.1%) C. jejuni isolates exhibited multidrug resistance. The chicken meat isolates of Estonian origin were the most susceptible. However, a high proportion of fluoroquinolone-resistant C. jejuni isolates were found in Latvian and Lithuanian products. The results of this study indicate that the problems caused by the inappropriate use of antimicrobials extend beyond the country in which a food originates; therefore, both domestic and international interventions and agreements are required to implement common policies on antimicrobial usage and to minimize the emergence of Campylobacter drug resistance.

  11. Local Authority Education in a Democratic Scotland.

    ERIC Educational Resources Information Center

    Fairley, John

    1998-01-01

    Establishment of a Scottish Parliament in 1999 will pose questions about its relationship to local authorities and their role in education. Possible scenarios are discussed in which Parliament pursues centralization or decentralization in education policy. Recent reforms to local government structures may allow local councils to become partners of…

  12. Greeks in America: Contributions to America, Relationship to Homeland, Integration into American Life, Retention of Ethnicity in America. Ethnic Heritage in America: Curriculum Materials in Elementary School Social Studies on Greeks, Jews, Lithuanians, and Ukrainians.

    ERIC Educational Resources Information Center

    Chicago Consortium for Inter-Ethnic Curriculum Development, IL.

    Part of the Ethnic Heritage in America curriculum materials, this unit is about Greeks in the United States. The first section presents basic facts, such as a map of Greece, map of Eastern Europe, facts about Greece, historical chronological outline, list of Greeks in U.S. history, bibliography about Greeks, Greek publications in the United…

  13. Ukrainians in America: Contributions to America, Relationship to Homeland, Integration into American Life, Retention of Ethnicity in America. Ethnic Heritage in America: Curriculum Materials in Elementary School Social Studies on Greeks, Jews, Lithuanians, and Ukrainians.

    ERIC Educational Resources Information Center

    Chicago Consortium for Inter-Ethnic Curriculum Development, IL.

    This ethnic heritage unit is about Ukrainians in the United States. The first section presents basic facts, such as a map of Ukraine, map of Eastern Europe, facts about Ukraine, principal dates in Ukrainian history, ten outstanding figures in modern Ukrainian history, milestones of Ukrainian communities in the United States, bibliography about…

  14. Jews in America: Contributions to America, Relationship to Homeland, Integration into American Life, Retention of Ethnicity in America. Ethnic Heritage in America: Curriculum Materials in Elementary School Social Studies on Greeks, Jews, Lithuanians, Ukrainians.

    ERIC Educational Resources Information Center

    Chicago Consortium for Inter-Ethnic Curriculum Development, IL.

    This ethnic heritage unit is about Jews in the United States. The first section presents basic facts, such as a map of Israel, map of Eastern Europe, facts about Israel, a bibliography about Jews, and a list of Jewish organizations in the United States. The second section discusses early Jewish settlement in North America, Jewish contributions to…

  15. Local Group

    NASA Astrophysics Data System (ADS)

    Mateo, M.; Murdin, P.

    2000-11-01

    Not long after EDWIN HUBBLE established that galaxies are `island universes' similar to our home galaxy, the MILKY WAY, he realized that a few of these external galaxies are considerably closer to us than any others. In 1936 he first coined the term `Local Group' in his famous book The Realm of the Nebulae to identify our nearest galactic neighbors. More than 60 yr later, the galaxies of the Loca...

  16. A novel hNIS/tdTomato fusion reporter for visualizing the relationship between the cellular localization of sodium iodide symporter and its iodine uptake function under heat shock treatment.

    PubMed

    Yeom, Chan Joo; Chung, Taemoon; Youn, Hyewon; Kang, Keon Wook; Lee, Dong Soo; Chung, June-Key

    2015-01-01

    The function of membrane-localized sodium iodide symporter (NIS) determines the efficacy of radioiodine therapy in thyroid cancer. Here, we describe a dual mode reporter fused with human NIS (hNIS) and a red fluorescent protein named tandem dimeric Tomato (tdTomato) for the in vitro and in vivo imaging of hNIS protein expression, localization, and iodide uptake function. Human cervical epithelial adenocarcinoma cell line (HeLa)-hNIS/tdTomato cells were established by transducing a fusion gene expressing hNIS/tdTomato under the control of a cytomegalovirus promoter. Fluorescence imaging, confocal microscopy, and an 125I uptake assay were performed to validate the integrity of the fusion protein. Actinomycin D and cycloheximide were used to block newly synthesized hNIS proteins. In vivo images were acquired using a gamma camera and a Maestro fluorescence imaging device. The fluorescence intensity of membrane-localized hNIS and 125I uptake both were increased after heat shock. Scintigraphy and fluorescence imaging indicated specific accumulation of the hNIS/tdTomato fusion protein in xenografted tumors, supporting the utility of this system for in vivo monitoring of hNIS expression and activity. We developed a novel hNIS/tdTomato dual mode reporter that enables visualization of the expression, localization, and iodine uptake function of hNIS in vitro and in vivo.

  17. Abusive Relationships

    MedlinePlus

    ... relationships and friendships. Emotional abuse (stuff like teasing, bullying, and humiliating others) can be difficult to recognize ... How to Break Up Respectfully Abuse Dealing With Bullying Date Rape Getting Over a Break-Up Posttraumatic ...

  18. Relationship between ferroelectric properties and local structure of Pb1-xBaxZr0.40Ti0.60O3 ceramic materials studied by X-ray absorption and Raman spectroscopies

    NASA Astrophysics Data System (ADS)

    Mesquita, Alexandre; Michalowicz, Alain; Moscovici, Jacques; Pizani, Paulo Sergio; Mastelaro, Valmor Roberto

    2016-08-01

    This paper reports on the structural characterization of Pb1-xBaxZr0.40Ti0.60O3 (PBZT) ferroelectric ceramic compositions prepared by the conventional solid state reaction method. X-ray absorption spectroscopy (XAS) and Raman spectroscopy were used in the probing of the local structure of PBZT samples that exhibit a normal or relaxor ferroelectric behavior. They showed a considerable local disorder around Zr and Pb atoms in the samples of tetragonal or cubic long-range order symmetry. The intensity of the E(TO3) mode in the Raman spectra of PBZT relaxor samples remains constant at temperatures lower than Tm, which has proven the stabilization of the correlation process between nanodomains.

  19. Quantum Locality?

    NASA Astrophysics Data System (ADS)

    Stapp, Henry P.

    2012-05-01

    , in response to Griffiths' challenge, why a putative proof of locality that he has described is flawed.

  20. Local Foods, Local Places Summary Reports

    EPA Pesticide Factsheets

    These summary reports describe Local Foods, Local Places projects in communities across the country, including farmers markets, cooperatives, community gardens, and other food-related enterprises that can boost local economies and drive revitalization.

  1. Quantum Locality?

    SciTech Connect

    Stapp, Henry

    2011-11-10

    vagaries that he cites do not upset the proof in question. It is show here in detail why the precise statement of this theorem justifies the specified application of CQT. It is also shown, in response to his challenge, why a putative proof of locality that he has proposed is not valid.

  2. The Local Education Fund. A Resource Guide.

    ERIC Educational Resources Information Center

    Public Education Fund, Pittsburgh, PA.

    A Local Education Fund (LEF) is a third-party, nonprofit entity whose agenda, at least in part, consists of developing supportive community and private sector relationships with a public school system. It provides limited private sector support to launch initiatives and broker relationships leading toward school improvement. LEFs are funded by the…

  3. Non-locality Sudden Death in Tripartite Systems

    SciTech Connect

    Jaeger, Gregg; Ann, Kevin

    2009-03-10

    Bell non-locality sudden death is the disappearance of non-local properties in finite times under local phase noise, which decoheres states only in the infinite-time limit. We consider the relationship between decoherence, disentanglement, and Bell non-locality sudden death in bipartite and tripartite systems in specific large classes of state preparation.

  4. History of Schooling: Politics and Local Practice

    ERIC Educational Resources Information Center

    Aubry, Carla, Ed.; Westberg, Johannes, Ed.

    2012-01-01

    The relationship between education policy and local practices is at the core of research pertaining to the history of education. In this volume, the authors examine this issue from a multitude of perspectives, presenting a broad and comprehensive picture of schooling on international, national and local levels. Three issues of great significance,…

  5. Stimulus-induced dissociation of neuronal firing rates and local field potential gamma power and its relationship to the blood oxygen level-dependent signal in macaque primary visual cortex

    PubMed Central

    Bartolo, M J; Gieselmann, M A; Vuksanovic, V; Hunter, D; Sun, L; Chen, X; Delicato, L S; Thiele, A

    2011-01-01

    The functional magnetic resonance imaging (fMRI) blood oxygenation level-dependent (BOLD) signal is regularly used to assign neuronal activity to cognitive function. Recent analyses have shown that the local field potential (LFP) gamma power is a better predictor of the fMRI BOLD signal than spiking activity. However, LFP gamma power and spiking activity are usually correlated, clouding the analysis of the neural basis of the BOLD signal. We show that changes in LFP gamma power and spiking activity in the primary visual cortex (V1) of the awake primate can be dissociated by using grating and plaid pattern stimuli, which differentially engage surround suppression and cross-orientation inhibition/facilitation within and between cortical columns. Grating presentation yielded substantial V1 LFP gamma frequency oscillations and significant multi-unit activity. Plaid pattern presentation significantly reduced the LFP gamma power while increasing population multi-unit activity. The fMRI BOLD activity followed the LFP gamma power changes, not the multi-unit activity. Inference of neuronal activity from the fMRI BOLD signal thus requires detailed a priori knowledge of how different stimuli or tasks activate the cortical network. PMID:22081989

  6. Relationship between productivity and resources

    SciTech Connect

    1995-10-01

    This portion of the Energy Vision 2020 draft report is a very brief discussion of the relationship between local short-term uses of the environment and enhancement of productivity. It also contains a brief mention of the irreversible and irretrievable commitments of resources.

  7. Social Partnership in Accrediting Lithuanian VET Qualifications

    ERIC Educational Resources Information Center

    Tutlys, Vidmantas; Kaminskiene, Lina

    2008-01-01

    This article examines social partnership in accrediting qualifications in Lithuania. It defines the factors influencing social partnership and surveys future development perspectives, referring to the creation and implementation of the national qualifications system in Lithuania. Social partnership in qualifications accreditation is regarded as a…

  8. Relationship between macroscopic physical properties and local distortions of low-doping La{sub 1-x}Ca{sub x}MnO{sub 3}: An EXAFS study

    SciTech Connect

    Jiang, Y.; Bridges, F.; Downward, L.; Neumeier, J. J.

    2007-12-01

    A temperature-dependent extended x-ray-absorption fine structure investigation of La{sub 1-x}Ca{sub x}MnO{sub 3} is presented for the concentration range that spans the ferromagnetic-insulator (FMI) to ferromagnetic-metal (FMM) transition region, x=0.16, 0.18, 0.20, and 0.22; the titrated hole concentrations are slightly higher, y=0.2, 0.22, 0.24, and 0.25, respectively. For this range of Ca concentrations the samples are insulating for x=0.16-0.2 and show a metal/insulator (M/I) transition for x=0.22. All samples are ferromagnetic although the saturation magnetization for the 16% Ca sample is only {approx}70% of the expected value at 0.4 T. This raises a question as to the nature of the ferromagnetic coupling mechanism in such insulating samples. We find that the FMI samples have similar correlations between changes in the local Mn-O distortions and the magnetization as observed previously for the colossal magnetoresistance (CMR) samples (0.2{<=}x{<=}0.5)--except that the FMI samples never become fully magnetized. The data show that there are at least two distinct types of distortions. The initial distortions removed as the insulating sample becomes magnetized are small and provide direct evidence that roughly 50% of the Mn sites (associated with the hole charge carriers) have a small average distortion/site and are magnetized first. The large Mn-O distortions that remain at low T are attributed to a small fraction (<30%) of fully Jahn-Teller-distorted Mn sites that are either unmagnetized or antiferromagnetically ordered. Thus the insulating samples are very similar to the behavior of the CMR samples up to the point at which the M/I transition occurs for the CMR materials. The lack of metallic conductivity for x{<=}0.2, when 50% or more of the sample is magnetic, implies that there must be preferred magnetized Mn sites (that involve holes) and that such sites do not percolate at these concentrations.

  9. Refuting phylogenetic relationships

    PubMed Central

    Bucknam, James; Boucher, Yan; Bapteste, Eric

    2006-01-01

    Background Phylogenetic methods are philosophically grounded, and so can be philosophically biased in ways that limit explanatory power. This constitutes an important methodologic dimension not often taken into account. Here we address this dimension in the context of concatenation approaches to phylogeny. Results We discuss some of the limits of a methodology restricted to verificationism, the philosophy on which gene concatenation practices generally rely. As an alternative, we describe a software which identifies and focuses on impossible or refuted relationships, through a simple analysis of bootstrap bipartitions, followed by multivariate statistical analyses. We show how refuting phylogenetic relationships could in principle facilitate systematics. We also apply our method to the study of two complex phylogenies: the phylogeny of the archaea and the phylogeny of the core of genes shared by all life forms. While many groups are rejected, our results left open a possible proximity of N. equitans and the Methanopyrales, of the Archaea and the Cyanobacteria, and as well the possible grouping of the Methanobacteriales/Methanoccocales and Thermosplasmatales, of the Spirochaetes and the Actinobacteria and of the Proteobacteria and firmicutes. Conclusion It is sometimes easier (and preferable) to decide which species do not group together than which ones do. When possible topologies are limited, identifying local relationships that are rejected may be a useful alternative to classical concatenation approaches aiming to find a globally resolved tree on the basis of weak phylogenetic markers. Reviewers This article was reviewed by Mark Ragan, Eugene V Koonin and J Peter Gogarten. PMID:16956399

  10. General relationships between ultrasonic attenuation and dispersion

    NASA Technical Reports Server (NTRS)

    Odonnell, M.; Jaynes, E. T.; Miller, J. G.

    1978-01-01

    General relationships between the ultrasonic attenuation and dispersion are presented. The validity of these nonlocal relationships hinges only on the properties of causality and linearity, and does not depend upon details of the mechanism responsible for the attenuation and dispersion. Approximate, nearly local relationships are presented and are demonstrated to predict accurately the ultrasonic dispersion in solutions of hemoglobin from the results of attenuation measurements.

  11. State Aid, Voter Power and Local Control in Education.

    ERIC Educational Resources Information Center

    Zak, Itai; Glasman, Naftaly S.

    1979-01-01

    Not only did voter power contribute meaningfully to local control behavior regardless of the exact shape of the relations between state aid and local control, but the hypothesized inverse relationship between state aid and local control did not receive support. Journal availability: see EA 511 898. (Author/IRT)

  12. Using a NIATx Based Local Learning Collaborative for Performance Improvement

    ERIC Educational Resources Information Center

    Roosa, Mathew; Scripa, Joseph S.; Zastowny, Thomas R.; Ford, James H., II

    2011-01-01

    Local governments play an important role in improving substance abuse and mental health services. The structure of the local learning collaborative requires careful attention to old relationships and challenges local governmental leaders to help move participants from a competitive to collaborative environment. This study describes one county's…

  13. Local reduction in physics

    NASA Astrophysics Data System (ADS)

    Rosaler, Joshua

    2015-05-01

    A conventional wisdom about the progress of physics holds that successive theories wholly encompass the domains of their predecessors through a process that is often called "reduction." While certain influential accounts of inter-theory reduction in physics take reduction to require a single "global" derivation of one theory's laws from those of another, I show that global reductions are not available in all cases where the conventional wisdom requires reduction to hold. However, I argue that a weaker "local" form of reduction, which defines reduction between theories in terms of a more fundamental notion of reduction between models of a single fixed system, is available in such cases and moreover suffices to uphold the conventional wisdom. To illustrate the sort of fixed-system, inter-model reduction that grounds inter-theoretic reduction on this picture, I specialize to a particular class of cases in which both models are dynamical systems. I show that reduction in these cases is underwritten by a mathematical relationship that follows a certain liberalized construal of Nagel/Schaffner reduction, and support this claim with several examples. Moreover, I show that this broadly Nagelian analysis of inter-model reduction encompasses several cases that are sometimes cited as instances of the "physicist's" limit-based notion of reduction.

  14. Climate and local abundance in freshwater fishes

    PubMed Central

    Knouft, Jason H.; Anthony, Melissa M.

    2016-01-01

    Identifying factors regulating variation in numbers of individuals among populations across a species' distribution is a fundamental goal in ecology. A common prediction, often referred to as the abundant-centre hypothesis, suggests that abundance is highest near the centre of a species' range. However, because of the primary focus on the geographical position of a population, this framework provides little insight into the environmental factors regulating local abundance. While range-wide variation in population abundance associated with environmental conditions has been investigated in terrestrial species, the relationship between climate and local abundance in freshwater taxa across species' distributions is not well understood. We used GIS-based temperature and precipitation data to determine the relationships between climatic conditions and range-wide variation in local abundance for 19 species of North American freshwater fishes. Climate predicted a portion of the variation in local abundance among populations for 18 species. In addition, the relationship between climatic conditions and local abundance varied among species, which is expected as lineages partition the environment across geographical space. The influence of local habitat quality on species persistence is well documented; however, our results also indicate the importance of climate in regulating population sizes across a species geographical range, even in aquatic taxa. PMID:27429769

  15. Climate and local abundance in freshwater fishes.

    PubMed

    Knouft, Jason H; Anthony, Melissa M

    2016-06-01

    Identifying factors regulating variation in numbers of individuals among populations across a species' distribution is a fundamental goal in ecology. A common prediction, often referred to as the abundant-centre hypothesis, suggests that abundance is highest near the centre of a species' range. However, because of the primary focus on the geographical position of a population, this framework provides little insight into the environmental factors regulating local abundance. While range-wide variation in population abundance associated with environmental conditions has been investigated in terrestrial species, the relationship between climate and local abundance in freshwater taxa across species' distributions is not well understood. We used GIS-based temperature and precipitation data to determine the relationships between climatic conditions and range-wide variation in local abundance for 19 species of North American freshwater fishes. Climate predicted a portion of the variation in local abundance among populations for 18 species. In addition, the relationship between climatic conditions and local abundance varied among species, which is expected as lineages partition the environment across geographical space. The influence of local habitat quality on species persistence is well documented; however, our results also indicate the importance of climate in regulating population sizes across a species geographical range, even in aquatic taxa.

  16. Locally epistatic genomic relationship matrices for genomic association

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In plant and animal breeding studies a distinction is made between the genetic value (additive + epistatic genetic effects) and the breeding value (additive genetic effects) of an individual since it is expected that some of the epistatic genetic effects will be lost due to recombination. In this pa...

  17. [Emergencies evolving from local anesthesia].

    PubMed

    Kaufman, E; Garfunkel, A; Findler, M; Elad, S; Zusman, S P; Malamed, S F; Galili, D

    2002-01-01

    Local anesthesia is without doubt the most frequently used drug in dentistry and in medicine. In spite of records of safety set by using these drugs, there is evidence to adverse reactions ranging from 2.5%-11%. Most of the reactions originate from the autonomic system. A recent, well-planned study indicates that adverse reactions are highly correlated to the medical status of the patient: the higher the medical risk, the greater the chance to experience an adverse reaction. This study also found that adverse reactions highly correlated to the concentration of adrenalin. Another recent study found a direct relationship between adverse reactions and the level of anxiety experienced by the patient and to the dental procedure. Most of the reactions in this study occurred either immediately at injection time and within 2 hours following the injection. Since the beginning of last century, vasoconstrictors have been added to local anesthesia solutions in order to reduce toxicity and prologue activity of the LA. However, today it is commonly agreed that this addition to local anesthesia should not be administered to cardiac patients especially those suffering from refractory dysrhythmias, angina pectoris, post myocardial infarction (6 months) and uncontrolled hypertension. Other contraindications to vasoconstrictors are endocrine disorders such as hyperthyroidism, hyperfunction of the medullary adrenal (pheochromocytoma) and uncontrolled diabetes mellitus. Cross reactivity of local anesthetic solutions can occur with MAO inhibitors, non specific beta adrenergic blockers, tricyclic antidepressants, phenothiazides and cocaine abusers. Noradrenaline added to local anesthetics as a vasoconstrictor has been described as a trigger to a great increase in blood pressure and therefore has been forbidden for use in many countries. This paper describes 4 cases of severe complications following the injections of local anesthesia of which three ended in fatality.

  18. Local perturbations perturb—exponentially–locally

    SciTech Connect

    De Roeck, W. Schütz, M.

    2015-06-15

    We elaborate on the principle that for gapped quantum spin systems with local interaction, “local perturbations [in the Hamiltonian] perturb locally [the groundstate].” This principle was established by Bachmann et al. [Commun. Math. Phys. 309, 835–871 (2012)], relying on the “spectral flow technique” or “quasi-adiabatic continuation” [M. B. Hastings, Phys. Rev. B 69, 104431 (2004)] to obtain locality estimates with sub-exponential decay in the distance to the spatial support of the perturbation. We use ideas of Hamza et al. [J. Math. Phys. 50, 095213 (2009)] to obtain similarly a transformation between gapped eigenvectors and their perturbations that is local with exponential decay. This allows to improve locality bounds on the effect of perturbations on the low lying states in certain gapped models with a unique “bulk ground state” or “topological quantum order.” We also give some estimate on the exponential decay of correlations in models with impurities where some relevant correlations decay faster than one would naively infer from the global gap of the system, as one also expects in disordered systems with a localized groundstate.

  19. South African Adolescents' Constructions of Intimacy in Romantic Relationships

    ERIC Educational Resources Information Center

    Lesch, Elmien; Furphy, Claire

    2013-01-01

    Localized understandings of adolescent romantic relationships are needed to expand our knowledge of the diversity of adolescent romantic experiences and to challenge negative discourses of adolescent heterosexual relationships. This study explored the constructions of intimacy of 20 adolescent men and women in romantic relationships from one…

  20. Aging in Sweden: local variation, local control.

    PubMed

    Davey, Adam; Malmberg, Bo; Sundström, Gerdt

    2014-08-01

    Aging in Sweden has been uniquely shaped by its history-most notably the long tradition of locally controlled services for older adults. We considered how local variations and local control shape the experience of aging in Sweden and organized the paper into 3 sections. First, we examine aging in Sweden along demography, economy, and housing. Next, we trace the origins and development of the Swedish welfare state to consider formal supports (service provision) and informal supports (caregiving and receipt of care). Finally, we direct researchers to additional data resources for understanding aging in Sweden in greater depth. Sweden was one of the first countries to experience rapid population aging. Quality of life for a majority of older Swedes is high. Local control permits a flexible and adaptive set of services and programs, where emphasis is placed on improving the quality and targeting of services that have already reached a plateau as a function of population and expenditures.

  1. Renal anemia control in Lithuania: influence of local conditions and local guidelines.

    PubMed

    Ziginskiene, Edita; Kuzminskis, Vytautas; Petruliene, Kristina; Vaiciuniene, Ruta; Stankuviene, Asta; Bumblyte, Inga Arune

    2013-01-01

    Erythropoietin stimulating agents had a long haul in Lithuania--we had no epoetin till 1994 and there was no intravenous iron in 2001-2004. The aim of this study was to assess the changes of renal anemia control in hemodialysis patients from early independence of Lithuania till nowadays and to evaluate the link of anemia with hospitalization rates and survival and hemoglobin variability in association with mortality. In December of each year since 1996 all hemodialysis centers have been visited and data has been collected using special questionnaires. The history of renal anemia control in Lithuania was complicated; however, a significant improvement was achieved: 54.7% of hemodialysis patients reached the target hemoglobin; all patients have a possibility of treatment with epoetin and intravenous iron. The involuntary experiment with an intravenous iron occurred in Lithuania because of economic reasons and confirmed the significant role of intravenous iron in the management of renal anemia. Hemoglobin below 100 g/L was associated with a 2.5-fold increase in relative risk of death and 1.7-fold increase in relative risk of hospitalization in Lithuanian hemodialysis patients. Although hemoglobin variability was common in Lithuanian hemodialysis patients, we did not find the association between hemoglobin variability and all-cause mortality in our study.

  2. Improved Garvey-Kelson Local Relations

    NASA Astrophysics Data System (ADS)

    Collis, William J. M. F.

    2009-08-01

    We discuss methods of estimating atomic masses using Garvey—Kelson[1, 2] like local relations. We show that both the longitudinal and transverse Garvey—Kelson and all other relations can be derived from a simpler mass relationship between just 4 nuclides, C4.

  3. Time to Go Local!

    MedlinePlus

    ... Bar Home Current Issue Past Issues Time to Go Local! Past Issues / Winter 2007 Table of Contents ... MedlinePlus.gov health topic pages, you will find "Go Local" links that take you to information about ...

  4. Temporal Non-locality

    NASA Astrophysics Data System (ADS)

    Filk, Thomas

    2013-04-01

    In this article I investigate several possibilities to define the concept of "temporal non-locality" within the standard framework of quantum theory. In particular, I analyze the notions of "temporally non-local states", "temporally non-local events" and "temporally non-local observables". The idea of temporally non-local events is already inherent in the standard formalism of quantum mechanics, and Basil Hiley recently defined an operator in order to measure the degree of such a temporal non-locality. The concept of temporally non-local states enters as soon as "clock-representing states" are introduced in the context of special and general relativity. It is discussed in which way temporally non-local measurements may find an interesting application for experiments which test temporal versions of Bell inequalities.

  5. Localized Prostate Cancer

    MedlinePlus

    ... a decision aid for men with clinically localized prostate cancer (available at http://effectivehealthcare.ahrq.gov/prostate_da) ... A Decision Aid for Men With Clinically Localized Prostate Cancer Page 1 of 24 Introduction Men with clinically ...

  6. Learning from Software Localization.

    ERIC Educational Resources Information Center

    Guo, She-Sen

    2003-01-01

    Localization is the process of adapting a product to meet the language, cultural and other requirements of a specific target environment or market. This article describes ways in which software localization impacts upon curriculum, and discusses what students will learn from software localization. (AEF)

  7. Exponential Localization of Photons

    NASA Astrophysics Data System (ADS)

    Bialynicki-Birula, Iwo

    1998-06-01

    It is shown that photons can be localized in space with an exponential falloff of the energy density and photodetection rates. The limits of localization are determined by the fundamental Paley-Wiener theorem. A direct mathematical connection between the spatial localization of photons and the decay in time of quantum mechanical systems is established.

  8. Local Authorities and Higher Education in the Public Sector.

    ERIC Educational Resources Information Center

    Owen, J. G.

    1985-01-01

    The unsatisfactory position of some British local education authorities concerning their responsibilities for college student distribution and placement and their relationship with the National Advisory Body that manages manpower training policy is discussed. (MSE)

  9. Personality and Sibling Relationships.

    ERIC Educational Resources Information Center

    Furman, Wyndol; Lanthier, Richard P.

    1996-01-01

    This study examined the role personality variables play in sibling relationships. It proposed that the characteristics of sibling relationships are influenced by: family constellation variables such as birth order, gender, and age spacing; parent-child relationships including quality of relationship and parent management of siblings; and the…

  10. Local quantum thermal susceptibility

    PubMed Central

    De Pasquale, Antonella; Rossini, Davide; Fazio, Rosario; Giovannetti, Vittorio

    2016-01-01

    Thermodynamics relies on the possibility to describe systems composed of a large number of constituents in terms of few macroscopic variables. Its foundations are rooted into the paradigm of statistical mechanics, where thermal properties originate from averaging procedures which smoothen out local details. While undoubtedly successful, elegant and formally correct, this approach carries over an operational problem, namely determining the precision at which such variables are inferred, when technical/practical limitations restrict our capabilities to local probing. Here we introduce the local quantum thermal susceptibility, a quantifier for the best achievable accuracy for temperature estimation via local measurements. Our method relies on basic concepts of quantum estimation theory, providing an operative strategy to address the local thermal response of arbitrary quantum systems at equilibrium. At low temperatures, it highlights the local distinguishability of the ground state from the excited sub-manifolds, thus providing a method to locate quantum phase transitions. PMID:27681458

  11. Experiments with program locality.

    NASA Technical Reports Server (NTRS)

    Spirn, J. R.; Denning, P. J.

    1972-01-01

    Attempt to validate experimentally several intrinsic models for the concept of program locality. The models considered are a two-parameter simple locality model, a simple least recently used stack model, and an independent reference model. The first two models appear to produce good approximations to real world behavior, while the independent reference model, because of its static concept of locality, does very poorly. The working set is shown to be a good estimator of the simple two-parameters model's locality, provided that the locality does not change too rapidly. The working set exactly measures the locality in the case of the least recently used stack model and is thus nearly optimal for programs whose behavior can be closely approximated by this model.

  12. The privileged status of locality in consonant harmony.

    PubMed

    Finley, Sara

    2011-07-01

    While the vast majority of linguistic processes apply locally, consonant harmony appears to be an exception. In this phonological process, consonants share the same value of a phonological feature, such as secondary place of articulation. In sibilant harmony, [s] and [ʃ] ('sh') alternate such that if a word contains the sound [ʃ], all [s] sounds become [ʃ]. This can apply locally as a first-order or non-locally as a second-order pattern. In the first-order case, no consonants intervene between the two sibilants (e.g., [pisasu], [piʃaʃu]). In second-order case, a consonant may intervene (e.g., [sipasu], [ʃipaʃu]). The fact that there are languages that allow second-order non-local agreement of consonant features has led some to question whether locality constraints apply to consonant harmony. This paper presents the results from two artificial grammar learning experiments that demonstrate the privileged role of locality constraints, even in patterns that allow second-order non-local interactions. In Experiment 1, we show that learners do not extend first-order non-local relationships in consonant harmony to second-order nonlocal relationships. In Experiment 2, we show that learners will extend a consonant harmony pattern with second-order long distance relationships to a consonant harmony with first-order long distance relationships. Because second-order non-local application implies first-order non-local application, but first-order non-local application does not imply second-order non-local application, we establish that local constraints are privileged even in consonant harmony.

  13. Local Estuary Programs

    EPA Pesticide Factsheets

    This page provides information about Local Individual Estuary Programs including links to their NEP homepages, social media, Comprehensive Conservation and Management Plans, and state of the bay reports.

  14. Students' Learning Strategies: Statistical Types and Their Relationship with Computer Literacy

    ERIC Educational Resources Information Center

    Saparniene, Diana

    2006-01-01

    Purpose: The purpose of this article is to identify and describe existing students' statistical types by their learning strategies and to show the connection with factual computer literacy. Methodology: The empirical-experimental part of the present study is based on a series of diagnostic studies of 1004 surveyed Lithuanian students. The article…

  15. Sexual assault in dating relationships.

    PubMed

    Rhynard, J; Krebs, M; Glover, J

    1997-03-01

    This article focuses on acquaintance rape, which under Canadian law constitutes a form of sexual assault. Frequency of acquaintance rape often is underestimated due to under-reporting, resulting in a local perception that acquaintance rape rarely occurs in a small Canadian community. A survey was conducted to determine whether acquaintance rape does occur in this community. One hundred sixty-four male and female students from grades 8-12 completed a questionnaire. Twenty-six percent of respondents reported being forced into some type of sexual activity. Based on the survey, this article explores the type of force used, the relationship between acquaintance rape and use of alcohol and drugs, and the relationship between acquaintance rape and the ability to indicate to a partner to stop a behavior. Results confirmed a need to develop programs to prevent rather than merely respond to issues of sexual assault on a date.

  16. Local theory for Mott-Anderson localization

    NASA Astrophysics Data System (ADS)

    Sen, Sudeshna; Terletska, Hanna; Moreno, Juana; Vidhyadhiraja, N. S.; Jarrell, Mark

    2016-12-01

    The paramagnetic metallic phase of the Anderson-Hubbard model (AHM) is investigated using a nonperturbative local moment approach within the framework of dynamical mean-field theory with a typical medium. Our focus is on the breakdown of the metallic phase near the metal-insulators transition as seen in the single-particle spectra, scattering rates, and the associated distribution of Kondo scales. We demonstrate the emergence of a universal, underlying low-energy scale, TKpeak. This lies close to the peak of the distribution of Kondo scales obtained within the metallic phase of the paramagnetic AHM. Spectral dynamics for energies ω ≲TKpeak display Fermi liquid universality crossing over to an incoherent universal dynamics for ω ≫TKpeak in the scaling regime. Such universal dynamics indicate that within a local theory the low to moderately low-energy physics is governed by an effective, disorder renormalized Kondo screening.

  17. Localization of Interference Fringes.

    ERIC Educational Resources Information Center

    Simon, J. M.; Comastri, Silvia A.

    1980-01-01

    Discusses a proof for determining the localized fringes position arrived at when one considers the interference of two extended sources when one is able to observe fringes only at certain points in space. Shows how the localized fringes may be found in a device used to observe Newton's rings. (Author/CS)

  18. Local anesthesia: a review.

    PubMed

    Malamed, S F; Sykes, P; Kubota, Y; Matsuura, H; Lipp, M

    1992-01-01

    Local anesthetics are the most widely administered drugs in dentistry. Significant advances have been made in past decades that have greatly increased both the safety and the efficacy of these important drugs. This paper reviews the history of local anesthesia, pharmacokinetics and clinical implications, techniques, complications, and future directions in the quest for more effective pain control in dentistry.

  19. Local health traditions.

    PubMed

    Shankar, D

    1988-03-01

    A very systematic study made in Karjat, Maharasht (a tribal area in India) has found that in comparison with the official health care and primary health centers, the traditional health practices are far more comprehensive. However, although the local traditions are comprehensive in their 'scope', they nevertheless reveal several weaknesses when subjected to critical evaluation by the science of Ayurveda. For example, whereas some remedies are found to be sound, there are others that are incomplete, and some appear to be totally distorted. Similarly, the diagnostic abilities of local practitioners, while sound in some cases, are in several others found to be inadequate. As to the use of local herbs, whereas the local tradition has an amazing knowledge of local flora--the knowledge about properties of plants is in many cases incomplete. There are several reasons that may explain how and why these weaknesses have set in. 1st, the local traditions are 'oral' and in the natural course of things, oral traditions the world over have been found to decay over time. A 2nd, external, reason for the current decay of local traditions is the derision, neglect, and oppression they have suffered due to the intolerance of western scientific tradition. A 3rd reason for weaknesses in the local health stream is the breakdown of active links, during the last few centuries, with the mainstream science of Ayurveda.

  20. Local Power: Tribe & Township.

    ERIC Educational Resources Information Center

    Matlala, Padi; Moloi, Dudley

    1995-01-01

    Examines the service infrastructure of a rural township in South Africa and the struggle to acquire services like water and electricity. Discusses the interaction of a system of transitional local councils and tribal authorities in the face of local government elections. (LZ)

  1. Mechanisms Regulating Protein Localization.

    PubMed

    Bauer, Nicholas C; Doetsch, Paul W; Corbett, Anita H

    2015-10-01

    Cellular functions are dictated by protein content and activity. There are numerous strategies to regulate proteins varying from modulating gene expression to post-translational modifications. One commonly used mode of regulation in eukaryotes is targeted localization. By specifically redirecting the localization of a pool of existing protein, cells can achieve rapid changes in local protein function. Eukaryotic cells have evolved elegant targeting pathways to direct proteins to the appropriate cellular location or locations. Here, we provide a general overview of these localization pathways, with a focus on nuclear and mitochondrial transport, and present a survey of the evolutionarily conserved regulatory strategies identified thus far. We end with a description of several specific examples of proteins that exploit localization as an important mode of regulation.

  2. Local aggregation characteristics of microscale blood flows

    NASA Astrophysics Data System (ADS)

    Kaliviotis, Efstathios; Sherwood, Joseph M.; Dusting, Jonathan; Balabani, Stavroula

    2015-11-01

    Erythrocyte aggregation (EA) is an important aspect of microvascular flows affecting blood flow and viscosity. Microscale blood flows have been studied extensively in recent years using computational and microfluidic based approaches. However, the relationship between the local structural characteristics of blood and the velocity field has not been quantified. We report simultaneous measurements of the local velocity, aggregation and haematocrit distributions of human erythrocytes flowing in a microchannel. EA was induced using Dextran and flows were imaged using brightfield microscopy. Local aggregation characteristics were investigated using statistical and edge-detection image processing techniques while velocity profiles were obtained using PIV algorithms. Aggregation intensity was found to strongly correlate with local variations in velocity in both the central and wall regions of the channel. The edge detection method showed that near the side wall large aggregates are associated with high local velocities and low local shear rates. In the central region large aggregates occurred in regions of low velocity and high erythrocyte concentration. The results demonstrate the combined effect of haematocrit and velocity distributions on local aggregation characteristics.

  3. Local-scale dynamics and local drivers of bushmeat trade.

    PubMed

    Nyaki, Angela; Gray, Steven A; Lepczyk, Christopher A; Skibins, Jeffrey C; Rentsch, Dennis

    2014-10-01

    Bushmeat management policies are often developed outside the communities in which they are to be implemented. These policies are also routinely designed to be applied uniformly across communities with little regard for variation in social or ecological conditions. We used fuzzy-logic cognitive mapping, a form of participatory modeling, to compare the assumptions driving externally generated bushmeat management policies with perceptions of bushmeat trade dynamics collected from local community members who admitted to being recently engaged in bushmeat trading (e.g., hunters, sellers, consumers). Data were collected during 9 workshops in 4 Tanzanian villages bordering Serengeti National Park. Specifically, we evaluated 9 community-generated models for the presence of the central factors that comprise and drive the bushmeat trade and whether or not models included the same core concepts, relationships, and logical chains of reasoning on which bushmeat conservation policies are commonly based. Across local communities, there was agreement about the most central factors important to understanding the bushmeat trade (e.g., animal recruitment, low income, and scarcity of food crops). These matched policy assumptions. However, the factors perceived to drive social-ecological bushmeat trade dynamics were more diverse and varied considerably across communities (e.g., presence or absence of collaborative law enforcement, increasing human population, market demand, cultural preference). Sensitive conservation issues, such as the bushmeat trade, that require cooperation between communities and outside conservation organizations can benefit from participatory modeling approaches that make local-scale dynamics and conservation policy assumptions explicit. Further, communities' and conservation organizations' perceptions need to be aligned. This can improve success by allowing context appropriate policies to be developed, monitored, and appropriately adapted as new evidence is

  4. Local Solid Shape

    PubMed Central

    Koenderink, Jan; van Doorn, Andrea

    2015-01-01

    Local solid shape applies to the surface curvature of small surface patches—essentially regions of approximately constant curvatures—of volumetric objects that are smooth volumetric regions in Euclidean 3-space. This should be distinguished from local shape in pictorial space. The difference is categorical. Although local solid shape has naturally been explored in haptics, results in vision are not forthcoming. We describe a simple experiment in which observers judge shape quality and magnitude of cinematographic presentations. Without prior training, observers readily use continuous shape index and Casorati curvature scales with reasonable resolution. PMID:27648217

  5. Intimate Relationships and Psychopathology

    ERIC Educational Resources Information Center

    Whisman, Mark A.; Baucom, Donald H.

    2012-01-01

    Relationship functioning and individual mental health and well-being are strongly associated with one another. In this article, we first review the cross-sectional and longitudinal associations between relationship discord and various types of psychopathology, We then review findings suggesting that relationship discord is associated with poorer…

  6. Building Relationships through Exchange

    ERIC Educational Resources Information Center

    Primavera, Angi; Hall, Ellen

    2011-01-01

    From the moment of birth, children form and develop relationships with others in their world based on exchange. Children recognize that engaging in such encounters offers them the opportunity to enter into a relationship with another individual and to nurture that relationship through the exchange of messages and gifts, items and ideas. At Boulder…

  7. Local Governments Reimbursement Program

    EPA Pesticide Factsheets

    In the event of a release (or threatened release) of hazardous substances, EPA may provide a safety net of up to $25,000 per incident to local governments for expenses related to the release and associated emergency response measures.

  8. Stereotype locally convex spaces

    NASA Astrophysics Data System (ADS)

    Akbarov, S. S.

    2000-08-01

    We give complete proofs of some previously announced results in the theory of stereotype (that is, reflexive in the sense of Pontryagin duality) locally convex spaces. These spaces have important applications in topological algebra and functional analysis.

  9. Local Anesthetic Microcapsules.

    DTIC Science & Technology

    1981-04-15

    III Chemical Structure of Local Anesthetics 12 Table IV Processing Summary of Lidocaine Microencapsulation 15 Table V Lidocaine Microcapsule Size...Distribution 17 Table VI Processing Summary of Etidocaine Microencapsulation 18 Table VII Etidocaine Microcapsule Size Distribution 19 Table VIII Lidocaine...REPORT I PERIOD COVERED Annual Local Anesthetic Microcapsules 1 July 1980-30 March 1981 6. PERFORMING ORG. REPORT NUMBER 2106-1 7. AUTHOR() S

  10. Localization protected quantum order

    NASA Astrophysics Data System (ADS)

    Nandkishore, Rahul

    2015-03-01

    Many body localization occurs in isolated quantum systems, usually with strong disorder, and is marked by absence of dissipation, absence of thermal equilibration, and a memory of the initial conditions that survives in local observables for arbitrarily long times. The many body localized regime is a non-equilibrium, strongly disordered, non-self averaging regime that presents a new frontier for quantum statistical mechanics. In this talk, I point out that there exists a vast zoo of correlated many body localized states of matter, which may be classified using familiar notions of spontaneous symmetry breaking and topological order. I will point out that in the many body localized regime, spontaneous symmetry breaking can occur even at high energy densities in one dimensional systems, and topological order can occur even without a bulk gap. I will also discuss the phenomenology of imperfectly isolated many body localized systems, which are weakly coupled to a heat bath. I will conclude with a brief discussion of how these phenomena may best be detected in experiments. Collaborators: David Huse, S.L. Sondhi, Arijeet Pal, Vadim Oganesyan, A.C. Potter, Sarang Gopalakrishnan, S. Johri, R.N. Bhatt.

  11. Global network influences on local functional connectivity

    PubMed Central

    Snyder, Adam C.; Morais, Michael J.; Willis, Cory M.; Smith, Matthew A.

    2015-01-01

    A central neuroscientific pursuit is understanding neuronal interactions that support computations underlying cognition and behavior. Although neurons interact across disparate scales – from cortical columns to whole-brain networks – research has been restricted to one scale at a time. We measured local interactions through multi-neuronal recordings while accessing global networks using scalp EEG in rhesus macaques. We measured spike count correlation, an index of functional connectivity with computational relevance, and EEG oscillations, which have been linked to various cognitive functions. We found a surprising non-monotonic relationship between EEG oscillation amplitude and spike count correlation, contrary to the intuitive expectation of a direct relationship. With a widely-used network model we replicated these findings by incorporating a private signal targeting inhibitory neurons, a common mechanism proposed for gain modulation. Finally, we report that spike count correlation explains nonlinearities in the relationship between EEG oscillations and response time in a spatial selective attention task. PMID:25799040

  12. Locally differentiated cryptic pigmentation in the freshwater isopod Asellus aquaticus.

    PubMed

    Hargeby, A; Stoltz, J; Johansson, J

    2005-05-01

    A repeated pattern of background colour matching in animals is an indication that pigmentation may be cryptic. Here, we examine the relationship between pigmentation of the freshwater isopod Asellus aquaticus and background darkness in 29 lakes, wetlands and ponds in Southern Sweden. The results show that Asellus pigmentation was correlated with substrate darkness across all localities. In seven localities, in which two contrasting substrate types were noted, Asellus populations were differentiated with respect to pigmentation. These findings thus provide phenomenological support for cryptic pigmentation in Asellus. Pigmentation generally increased with body size, but the relationship between pigmentation and size differed among localities, possibly as a result of differences in correlational selection on pigmentation and size. Selection thus appears to have resulted in local differentiation over a small spatial scale, even within lakes and wetlands. This differentiation is a likely cause behind elevated phenotype variation noted in localities with two substrate types, suggesting that habitat heterogeneity promotes genetic diversity.

  13. The Impact of the College on the Local Economy. Research Report No. 11.

    ERIC Educational Resources Information Center

    Selgas, James W.; And Others

    Significant aspects of the economic relationships between the Harrisburg (Pennsylvania) Area Community College and the local community were studied, and quantitative information regarding such relationships is presented. The impact on business was measured in terms of increased cash flows in the local economy. Both an inclusive and a conservative…

  14. Local and global measures of shape dynamics

    NASA Astrophysics Data System (ADS)

    Driscoll, Meghan K.; Fourkas, John T.; Losert, Wolfgang

    2011-10-01

    The shape and motion of cells can yield significant insights into the internal operation of a cell. We present a simple, yet versatile, framework that provides multiple metrics of cell shape and cell shape dynamics. Analysis of migrating Dictyostelium discoideum cells shows that global and local metrics highlight distinct cellular processes. For example, a global measure of shape shows rhythmic oscillations suggestive of contractions, whereas a local measure of shape shows wave-like dynamics indicative of protrusions. From a local measure of dynamic shape, or boundary motion, we extract the times and locations of protrusions and retractions. We find that protrusions zigzag, while retractions remain roughly stationary along the boundary. We do not observe any temporal relationship between protrusions and retractions. Our analysis framework also provides metrics of the boundary as whole. For example, as the cell speed increases, we find that the cell shape becomes more elongated. We also observe that while extensions and retractions have similar areas, their shapes differ.

  15. Local magnitudes of small contained explosions.

    SciTech Connect

    Chael, Eric Paul

    2009-12-01

    The relationship between explosive yield and seismic magnitude has been extensively studied for underground nuclear tests larger than about 1 kt. For monitoring smaller tests over local ranges (within 200 km), we need to know whether the available formulas can be extrapolated to much lower yields. Here, we review published information on amplitude decay with distance, and on the seismic magnitudes of industrial blasts and refraction explosions in the western U. S. Next we measure the magnitudes of some similar shots in the northeast. We find that local magnitudes ML of small, contained explosions are reasonably consistent with the magnitude-yield formulas developed for nuclear tests. These results are useful for estimating the detection performance of proposed local seismic networks.

  16. Monaural Sound Localization Revisited

    NASA Technical Reports Server (NTRS)

    Wightman, Frederic L.; Kistler, Doris J.

    1997-01-01

    Research reported during the past few decades has revealed the importance for human sound localization of the so-called 'monaural spectral cues.' These cues are the result of the direction-dependent filtering of incoming sound waves accomplished by the pinnae. One point of view about how these cues are extracted places great emphasis on the spectrum of the received sound at each ear individually. This leads to the suggestion that an effective way of studying the influence of these cues is to measure the ability of listeners to localize sounds when one of their ears is plugged. Numerous studies have appeared using this monaural localization paradigm. Three experiments are described here which are intended to clarify the results of the previous monaural localization studies and provide new data on how monaural spectral cues might be processed. Virtual sound sources are used in the experiments in order to manipulate and control the stimuli independently at the two ears. Two of the experiments deal with the consequences of the incomplete monauralization that may have contaminated previous work. The results suggest that even very low sound levels in the occluded ear provide access to interaural localization cues. The presence of these cues complicates the interpretation of the results of nominally monaural localization studies. The third experiment concerns the role of prior knowledge of the source spectrum, which is required if monaural cues are to be useful. The results of this last experiment demonstrate that extraction of monaural spectral cues can be severely disrupted by trial-to-trial fluctuations in the source spectrum. The general conclusion of the experiments is that, while monaural spectral cues are important, the monaural localization paradigm may not be the most appropriate way to study their role.

  17. 28 CFR 35.103 - Relationship to other laws.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (including State common law) that provide greater or equal protection for the rights of individuals with... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Relationship to other laws. 35.103... IN STATE AND LOCAL GOVERNMENT SERVICES General § 35.103 Relationship to other laws. (a) Rule...

  18. 28 CFR 35.103 - Relationship to other laws.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Relationship to other laws. 35.103 Section 35.103 Judicial Administration DEPARTMENT OF JUSTICE NONDISCRIMINATION ON THE BASIS OF DISABILITY IN STATE AND LOCAL GOVERNMENT SERVICES General § 35.103 Relationship to other laws. (a) Rule...

  19. 28 CFR 35.103 - Relationship to other laws.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Relationship to other laws. 35.103 Section 35.103 Judicial Administration DEPARTMENT OF JUSTICE NONDISCRIMINATION ON THE BASIS OF DISABILITY IN STATE AND LOCAL GOVERNMENT SERVICES General § 35.103 Relationship to other laws. (a) Rule...

  20. 2 CFR 225.45 - Relationship to previous issuance.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Relationship to previous issuance. 225.45 Section 225.45 Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET CIRCULARS AND GUIDANCE Reserved COST PRINCIPLES FOR STATE, LOCAL, AND INDIAN TRIBAL GOVERNMENTS (OMB CIRCULAR A-87) § 225.45 Relationship...

  1. 28 CFR 35.103 - Relationship to other laws.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Relationship to other laws. 35.103... IN STATE AND LOCAL GOVERNMENT SERVICES General § 35.103 Relationship to other laws. (a) Rule of... regulations issued by Federal agencies pursuant to that title. (b) Other laws. This part does not...

  2. 28 CFR 35.103 - Relationship to other laws.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Relationship to other laws. 35.103... IN STATE AND LOCAL GOVERNMENT SERVICES General § 35.103 Relationship to other laws. (a) Rule of... regulations issued by Federal agencies pursuant to that title. (b) Other laws. This part does not...

  3. The Complex Relationship Between Diet And Health.

    PubMed

    Bleich, Sara N; Jones-Smith, Jessica; Wolfson, Julia A; Zhu, Xiaozhou; Story, Mary

    2015-11-01

    The relationship between food and health is complex. Everyone needs food to live, but too little food, too much food, or the wrong type of food has negative consequences for health. To increase understanding of this relationship, we describe trends and patterns in food-related diseases among both adults and children. Using an ecological framework, we then describe why food intake is complex with a discussion of three broad levels--macro (including policy and social-cultural norms), local community, and individual environments--and their relationship to food consumption. Given the strong relationship between an individual's food choice and his or her surrounding environment, we end with examples of policy responses that aim to help people overcome environmental disincentives toward healthy eating. Finding ways to make eating healthfully easier and affordable for all populations is essential to shifting the average American diet toward one that promotes health.

  4. State and Local Government Partnership

    SciTech Connect

    Barton, Alexander; Rinebold, Joel; Aresta, Paul

    2012-03-30

    The State and Local Government Partnership project has built relationships between the Department of Energy (DOE), regional states, and municipalities. CCAT implemented this project using a structure that included leadership by the DOE. Outreach was undertaken through collaborative meetings, workshops, and briefings; the development of technical models and local energy plans; support for state stakeholder groups; and implementation of strategies to facilitate the deployment of hydrogen and fuel cell technologies. The final guidance documents provided to stakeholders consisted of individual strategic state “Roadmaps” to serve as development plans. These “Roadmaps” confirm economic impacts, identify deployment targets, and compare policies and incentives for facility development in each of the regional states. The partnerships developed through this project have improved the exchange of knowledge between state and local government stakeholders and is expected to increase the deployment of hydrogen and fuel cell technologies in early market applications, consistent with the DOE’s market transformation efforts. Technically accurate and objective information was, and continues to be, provided to improve public and stakeholder perceptions regarding the use of hydrogen and fuel cell technologies. Based on the “Roadmaps” and studies conducted for this project, there is the potential to generate approximately 10.75 million megawatt hours (MWh) of electricity annually from hydrogen and fuel cell technologies at potential host sites in the Northeast regional states, through the development of 1,364 to 1,818 megawatts (MW) of fuel cell electric generation capacity. Currently, the region has approximately 1,180 companies that are part of the growing hydrogen and fuel cell industry supply chain in the region. These companies are estimated to have over $1 billion in annual revenue and investment, contribute more than $51 million in annual state and local tax revenue

  5. Representing properties locally.

    PubMed

    Solomon, K O; Barsalou, L W

    2001-09-01

    Theories of knowledge such as feature lists, semantic networks, and localist neural nets typically use a single global symbol to represent a property that occurs in multiple concepts. Thus, a global symbol represents mane across HORSE, PONY, and LION. Alternatively, perceptual theories of knowledge, as well as distributed representational systems, assume that properties take different local forms in different concepts. Thus, different local forms of mane exist for HORSE, PONY, and LION, each capturing the specific form that mane takes in its respective concept. Three experiments used the property verification task to assess whether properties are represented globally or locally (e.g., Does a PONY have mane?). If a single global form represents a property, then verifying it in any concept should increase its accessibility and speed its verification later in any other concept. Verifying mane for PONY should benefit as much from having verified mane for LION earlier as from verifying mane for HORSE. If properties are represented locally, however, verifying a property should only benefit from verifying a similar form earlier. Verifying mane for PONY should only benefit from verifying mane for HORSE, not from verifying mane for LION. Findings from three experiments strongly supported local property representation and ruled out the interpretation that object similarity was responsible (e.g., the greater overall similarity between HORSE and PONY than between LION and PONY). The findings further suggest that property representation and verification are complicated phenomena, grounded in sensory-motor simulations.

  6. Local critical power is an index of local endurance.

    PubMed

    Le Chevalier, J M; Vandewalle, H; Thépaut-Mathieu, C; Stein, J F; Caplan, L

    2000-01-01

    The hypothesis that critical power (CP) is significantly lower than the maximal aerobic power of the knee extensors has been tested in nine endurance-trained subjects, seven gymnasts and seven weight lifters. CP was calculated as being equal to the slope of the linear relationship between exhaustion time and work performed at exhaustion on a knee-extension ergometer. CP was compared with the power output at the end of a progressive knee-extension exercise (P(peak)) and the power outputs corresponding to exhaustion times equal to 4 (P(4 min)), 6 (P(6 min)), 8 (P(8 min)) and 10 min (P(10 min)), calculated according to the linear relationship between work and exhaustion time. The hypothesis that CP corresponds to a steady state in metabolic and physiological parameters was tested in the gymnasts and the weight lifters by comparing CP with the fatigue thresholds of the integrated electromyogram (iEMG(FT)), lactate level (La(FT)), oxygen uptake (VO(2FT)) and heart rate (HR(FT)). The results of the present study demonstrate that the value of CP of a local exercise cannot be considered as the equivalent of the maximal aerobic power for general exercises. The values of P(4 min), P(6 min), P(8 min), P(10 min) and P(peak) were significantly higher than CP, and corresponded to 138, 126, 119, 115 and 151% CP, respectively. The results of the present study indicate that CP can be considered as an index of muscular endurance. Indeed, La(FT), iEMG (FT), VO(2FT) and HR(FT) were not significantly different from CP. All of these fatigue thresholds were significantly correlated with CP (r > 0.92). Moreover, the highest coefficient of correlation (r=0.71; P < 0.01) between the percentage of maximal aerobic power in cycling that corresponds to a blood lactate concentration of 4 mmol x l(-1) (OBLA%) and the different local aerobic indices was observed with CP.

  7. Frequently Asked Questions (FAQs) About Local Foods, Local Places

    EPA Pesticide Factsheets

    Answers to frequently asked questions about EPA's Local Foods, Local Places planning assistance program to help communities revitalize downtowns, create economic opportunities, and improve access to healthy food by promoting local foods.

  8. Local Foods, Local Places 2016-2017 Application

    EPA Pesticide Factsheets

    2016-2017 application for Local Foods, Local Places, technical assistance that helps communities use local foods to create walkable and economically vibrant districts, boost economic opportunities, and improve access to healthy foods.

  9. Robust and Secure Localization

    DTIC Science & Technology

    2009-06-03

    attacker-chosen location to the nodes as they are deployed.  establish wormhole links and tunnel legitimate messages to distant locations in the...network which are beyond the radio range of the source nodes. The wormhole attack can potentially introduce significant localization error of any node

  10. Teaching Local History.

    ERIC Educational Resources Information Center

    Singer, Alan, Ed.

    2003-01-01

    This Social Science Docket theme issue focuses on teaching local history and included theme and non-themed articles, lesson plans, learning activities, and book, movie, and museum reviews designed for K-12 social studies teachers. Articles and materials in this issue are: "Editing Is Not Censorship" (Alan Singer); "Teachers Respond…

  11. Principle of relative locality

    SciTech Connect

    Amelino-Camelia, Giovanni; Freidel, Laurent; Smolin, Lee; Kowalski-Glikman, Jerzy

    2011-10-15

    We propose a deepening of the relativity principle according to which the invariant arena for nonquantum physics is a phase space rather than spacetime. Descriptions of particles propagating and interacting in spacetimes are constructed by observers, but different observers, separated from each other by translations, construct different spacetime projections from the invariant phase space. Nonetheless, all observers agree that interactions are local in the spacetime coordinates constructed by observers local to them. This framework, in which absolute locality is replaced by relative locality, results from deforming energy-momentum space, just as the passage from absolute to relative simultaneity results from deforming the linear addition of velocities. Different aspects of energy-momentum space geometry, such as its curvature, torsion and nonmetricity, are reflected in different kinds of deformations of the energy-momentum conservation laws. These are in principle all measurable by appropriate experiments. We also discuss a natural set of physical hypotheses which singles out the cases of energy-momentum space with a metric compatible connection and constant curvature.

  12. Local Area Networks.

    ERIC Educational Resources Information Center

    Bullard, David

    1983-01-01

    The proliferation of word processors, micro- and minicomputer systems, and other digital office equipment is causing major design changes in existing networks. Local Area Networks (LANs) which have adequately served terminal users in the past must now be redesigned. Implementation at Clemson is described. (MLW)

  13. Local Area Networks.

    ERIC Educational Resources Information Center

    Marks, Kenneth E.; Nielsen, Steven

    1991-01-01

    Discusses cabling that is needed in local area networks (LANs). Types of cables that may be selected are described, including twisted pair, coaxial cables (or ethernet), and fiber optics; network topologies, the manner in which the cables are laid out, are considered; and cable installation issues are discussed. (LRW)

  14. Local Area Networks.

    ERIC Educational Resources Information Center

    Nasatir, Marilyn; And Others

    1990-01-01

    Four papers discuss LANs (local area networks) and library applications: (1) "Institute for Electrical and Electronic Engineers Standards..." (Charles D. Brown); (2) "Facilities Planning for LANs..." (Gail Persky); (3) "Growing up with the Alumni Library: LAN..." (Russell Buchanan); and (4) "Implementing a LAN...at the Health Sciences Library"…

  15. Tackling a Local Problem.

    ERIC Educational Resources Information Center

    Cook, Martin

    1995-01-01

    Students studying water as a class project were concerned by levels of pollution at a nearby river and the local beach. They identified three environmental problems for research including sewage discharge, beach litter, and quality of swimming water. Research consisted of field trips which allowed for opportunities to improve skills in collecting…

  16. Dynamic localized load balancing

    NASA Astrophysics Data System (ADS)

    Balandin, Sergey I.; Heiner, Andreas P.

    2003-08-01

    Traditionally dynamic load balancing is applied in resource-reserved connection-oriented networks with a large degree of managed control. Load balancing in connectionless networks is rather rudimentary and is either static or requires network-wide load information. This paper presents a fully automated, traffic driven dynamic load balancing mechanism that uses local load information. The proposed mechanism is easily deployed in a multi-vendor environment in which only a subset of routers supports the function. The Dynamic Localized Load Balancing (DLLB) mechanism distributes traffic based on two sets of weights. The first set is fixed and is inverse proportional to the path cost, typically the sum of reciprocal bandwidths along the path. The second weight reflects the utilization of the link to the first next hop along the path, and is therefore variable. The ratio of static weights defines the ideal load distribution, the ratio of variable weights the node-local load distribution estimate. By minimizing the difference between variable and fixed ratios the traffic distribution, with the available node-local knowledge, is optimal. The above mechanism significantly increases throughput and decreases delay from a network-wide perspective. Optionally the variable weight can include load information of nodes downstream to prevent congestion on those nodes. The latter function further improves network performance, and is easily implemented on top of the standard OSPF signaling. The mechanism does not require many node resources and can be implemented on existing router platforms.

  17. Local anesthetic update.

    PubMed Central

    MacKenzie, T. A.; Young, E. R.

    1993-01-01

    The development of new local anesthetics has not been an area of particularly active research for a number of years. However, as the use of regional anesthesia has expanded, additional anesthetic requirements and techniques have stimulated the search for newer drugs and ways of modifying existing ones. This article reviews some of the more recent developments in this field. PMID:8185087

  18. Global and Local Textuality.

    ERIC Educational Resources Information Center

    Campbell, B. G.

    Coherence and cohesion are fundamental considerations of the composing process that help to define the global and local components of texuality. Global text coherence centers on those aspects of the familiar rhetorical situation. Coherence operates at the paragraph and essay levels, answering questions about focus, tone, mode, topic, and thesis.…

  19. Both phototropin 1 and 2 localize on the chloroplast outer membrane with distinct localization activity.

    PubMed

    Kong, Sam-Geun; Suetsugu, Noriyuki; Kikuchi, Shingo; Nakai, Masato; Nagatani, Akira; Wada, Masamitsu

    2013-01-01

    Chloroplasts change their position to adapt cellular activities to fluctuating environmental light conditions. Phototropins (phot1 and phot2 in Arabidopsis) are plant-specific blue light photoreceptors that perceive changes in light intensity and direction, and mediate actin-based chloroplast photorelocation movements. Both phot1 and phot2 regulate the chloroplast accumulation response, while phot2 is mostly responsible for the regulation of the avoidance response. Although it has been widely accepted that distinct intracellular localizations of phototropins are implicated in the specificity, the mechanism underlying the phot2-specific avoidance response has remained elusive. In this study, we examined the relationship of the phot2 localization pattern to the chloroplast photorelocation movement. First, the fusion of a nuclear localization signal with phot2, which effectively reduced the amount of phot2 in the cytoplasm, retained the activity for both the accumulation and avoidance responses, indicating that membrane-localized phot2 but not cytoplasmic phot2 is functional to mediate the responses. Importantly, some fractions of phot2, and of phot1 to a lesser extent, were localized on the chloroplast outer membrane. Moreover, the deletion of the C-terminal region of phot2, which was previously shown to be defective in blue light-induced Golgi localization and avoidance response, affected the localization pattern on the chloroplast outer membrane. Taken together, these results suggest that dynamic phot2 trafficking from the plasma membrane to the Golgi apparatus and the chloroplast outer membrane might be involved in the avoidance response.

  20. Rural-to-urban migrant adolescents in Guangzhou, China: psychological health, victimization, and local and trans-local ties.

    PubMed

    Cheung, Nicole W T

    2013-09-01

    Despite the emerging literature on the health of rural-to-urban migrant children in China, few studies have addressed victimization stressors and stress-buffering mechanisms related to the social relationships that link migrants to their host cities (local ties) and home communities (trans-local ties). This study compared rural-to-urban migrant adolescents and urban native adolescents to examine the relationships between victimization, local and trans-local ties, and mental well-being that might be unique to migrants. Participants were 482 migrant students and 838 urban native students in the eighth grade in Guangzhou who completed a school-based survey in spring 2011. Victimization was associated with suboptimal psychological health in both the migrant and urban native samples. Social ties directly boosted psychological health in both samples, with the effects of trans-local and local ties proving equally important among migrant adolescents. While both local and trans-local ties moderated the effect of victimization on migrant adolescents, that moderation mattered less for urban native youth. These results highlight that a better understanding of victimization stress and how it is affected by the locality of social ties as a coping resource could help to protect the health of young migrants in urban China.

  1. Characteristics of Successful Local Blended Programs in the Context of the Sloan-C Pillars

    ERIC Educational Resources Information Center

    Moloney, Jacqueline F.; Hickey, Charmaine P.; Bergin, Amy L.; Boccia, Judith; Polley, Kathleen; Riley, Jeannette E.

    2007-01-01

    Drawing on the University of Massachusetts experience in developing successful blended local programs, this paper suggests guiding principles that include mission-driven responsiveness to local contexts and partnerships; using low-cost marketing strategies available through local relationships and brand; attending to students' preferences for…

  2. Characteristics of Successful Local Blended Programs in the Context of the Sloan-C Pillars

    ERIC Educational Resources Information Center

    Moloney, Jacqueline F.; Hickey, Charmaine P.; Bergin, Amy L.; Boccia, Judith; Polley, Kathleen; Riley, Jeannette E.

    2010-01-01

    Drawing on the University of Massachusetts experience in developing successful blended local programs, this paper suggests guiding principles that include mission-driven responsiveness to local contexts and partnerships; using low-cost marketing strategies available through local relationships and brand; attending to students' preferences for…

  3. The Crucial Coaching Relationship

    ERIC Educational Resources Information Center

    Scales, Peter C.

    2016-01-01

    One of the most powerful ways to boost the payoff from school sports lays in helping coaches build developmental relationships with student-athletes. Developmental relationships are close connections through which young people develop character skills to discover who they are, gain the ability to shape their own lives, and learn how to interact…

  4. Relationship Building Blocks

    ERIC Educational Resources Information Center

    Santabarbara, Todd; Erbe, Ryan; Cooper, Scott

    2009-01-01

    Intimate or romantic relationships for young people today play an integral role in their health and quality of life. Between the ages of 11 and 13 students become more interested in the opposite sex and as a result they begin to develop more intimate relationships. Around this age students are learning to deal with these feelings of attraction and…

  5. Partners: Forging Strong Relationships.

    ERIC Educational Resources Information Center

    Spears, Ellen, Ed.

    1999-01-01

    This newsletter issue asserts that sound, effective relationships in which diverse groups of people and organizations work together toward a common goal are the basis of the collaborative efforts in education that can accomplish change. The first article, "Partners: Forging Strong Relationships" (Sarah E. Torian), briefly describes the…

  6. Building Relationships with Parents

    ERIC Educational Resources Information Center

    Cullaj, Stephanie

    2015-01-01

    Communicating with parents may seem like one more task on top of an overwhelming workload, but creating a positive relationship with parents has many benefits for all involved. The author discusses the steps to creating these relationships and communicating with families.

  7. University-Community Relationships.

    ERIC Educational Resources Information Center

    Fink, Ira

    1986-01-01

    Common issues in university-community relationships, such as neighborhood problems and their solutions, facility expansion, traffic and parking, crime, housing, recreation facilities, and city services, are discussed. Findings from a study of the university-community relationship at Ohio State University are outlined. (MSE)

  8. Doctor-patient relationship

    PubMed Central

    Chamsi-Pasha, Hassan; Albar, Mohammed A.

    2016-01-01

    The doctor-patient relationship is an intricate concept in which patients voluntarily approach a doctor and become part of a contract by which they tend to abide by doctor’s instructions. Over recent decades, this relationship has changed dramatically due to privatization and commercialization of the health sector. A review of the relevant literature in the database of MEDLINE published in English between 1966 and August 2015 was performed with the following keywords: doctor-patient relationship, physician-patient relationship, ethics, and Islam. The Muslim doctor should be familiar with the Islamic teachings on the daily issues faced in his/her practice and the relationship with his/her patients. PMID:26837392

  9. Macroecology of biodiversity: disentangling local and regional effects.

    PubMed

    Pärtel, Meelis; Bennett, Jonathan A; Zobel, Martin

    2016-07-01

    Contents 404 I. 404 II. 404 III. 405 IV. 406 V. 407 VI. 408 409 References 409 SUMMARY: Macroecology of biodiversity disentangles local and regional drivers of biodiversity by exploring large-scale biodiversity relationships with environmental or biotic gradients, generalizing local biodiversity relationships across regions, or comparing biodiversity patterns among species groups. A macroecological perspective is also important at local scales: a full understanding of local biodiversity drivers, including human impact, demands that regional processes be taken into account. This requires knowledge of which species could inhabit a site (the species pool), including those that are currently absent (dark diversity). Macroecology of biodiversity is currently advancing quickly owing to an unprecedented accumulation of biodiversity data, new sampling techniques and analytical methods, all of which better equip us to face current and future challenges in ecology and biodiversity conservation.

  10. Broadband local dielectric spectroscopy

    NASA Astrophysics Data System (ADS)

    Labardi, M.; Lucchesi, M.; Prevosto, D.; Capaccioli, S.

    2016-05-01

    A route to extend the measurement bandwidth of local dielectric spectroscopy up to the MHz range has been devised. The method is based on a slow amplitude modulation at a frequency Ω of the excitation field oscillating at a frequency ω and the coherent detection of the modulated average electric force or force gradient at Ω. The cantilever mechanical response does not affect the measurement if Ω is well below its resonant frequency; therefore, limitations on the excitation field frequency are strongly reduced. Demonstration on a thin poly(vinyl acetate) film is provided, showing its structural relaxation spectrum on the local scale up to 45 °C higher than glass temperature, and nanoscale resolution dielectric relaxation imaging near conductive nanowires embedded in the polymer matrix was obtained up to 5 MHz frequency, with no physical reason to hinder further bandwidth extension.

  11. Local normal galaxies

    NASA Technical Reports Server (NTRS)

    Fichtel, Carl E.

    1990-01-01

    In the near future, high energy (E greater than 20 MeV) gamma ray astronomy offers the promise of a new means of examining the closest galaxies. Two and possibly three local galaxies, the Small and Large Magellanic Clouds and M31, should be visible to the high energy gamma ray telescope on the Gamma Ray Observatory, and the first should be seen by GAMMA-1. With the assumptions of adequate cosmic ray production and reasonable magnetic field strengths, both of which should likely be satisfied, specific predictions of the gamma ray emission can be made separating the concepts of the galactic and universal nature of cosmic rays. A study of the synchrotron radiation from the Large Magellanic Cloud (LMC) suggests that the cosmic ray density is similar to that in the local region of our galaxy, but not uniform. It is hoped the measurements will be able to verify this independent of assumptions about the magnetic fields in the LMC.

  12. Stable local oscillator module.

    SciTech Connect

    Brocato, Robert Wesley

    2007-11-01

    This report gives a description of the development of a Stable Local Oscillator (StaLO) multi-chip module (MCM). It is a follow-on report to SAND2006-6414, Stable Local Oscillator Microcircuit. The StaLO accepts a 100MHz input signal and produces output signals at 1.2, 3.3, and 3.6 GHz. The circuit is built as a multi-chip module (MCM), since it makes use of integrated circuit technologies in silicon and lithium niobate as well as discrete passive components. This report describes the development of an MCM-based version of the complete StaLO, fabricated on an alumina thick film hybrid substrate.

  13. THz Local Oscillator Technology

    NASA Technical Reports Server (NTRS)

    Mehdi, Imran

    2004-01-01

    The last decade has seen a number of technological advancements that have now made it possible to implement fully solid state local oscillator chains up to 2 THz. These chains are composed of cascaded planar multiplier stages that are pumped with W-band high power sources. The high power W-band sources are achieved by power combining MMIC amplifiers and can provide in access of 150 mW with about 10% bandwidth. Planar diode technology has also enabled novel circuit topologies that can take advantage of the high input power and demonstrate significant efficiencies well into the THz range. Cascaded chains to 1.9 THz have now been demonstrated with enough output power to successfully pump hot-electron bolometer mixers in this frequency range. An overview of the current State-of-the-Art of the local oscillator technology will be presented along with highlighting future trends and challenges.

  14. Local Anesthetic Microencapsulation.

    DTIC Science & Technology

    1983-11-04

    tollowing I.M. injection of microencapsulated lidocaine and etidocaine than following solution injections. Local toxicity of these microcapsule injections...Distribution 41 Table 12 Processing Summary of Lidocaine (Base) 43 Microencapsulation Table 13 Lidocaine (Base) Microcapsule Size 44 Distribution...Table 14 Processing Summary of Et’idocaine-HCl 45 Microencapsulation Table 15 Etidocaine-HCl Microcapsule Size 47 Distribution Table 16 Process Summary

  15. Local Rotational Symmetries.

    DTIC Science & Technology

    1985-08-01

    spanner wrench and the teaspoon, the pointed jaws of the wrench, and the main axes of the gourd , the pear, the squash, and the bowl of the teaspoon...regions such as the handle of the spanner wrench and the main axes of the gourd , squash, and teaspoon, and also pointed regions such as the end of the...Local Symmetry representation does not provide in- tuitively acceptable analyses for round regions, such as the lemon and the round ends of the gourd

  16. The Local Dark Matter

    SciTech Connect

    Helfer, H.L.

    2005-10-21

    The observations of the extended rotation curves of some galaxies provide important constraints upon the nature of the local dark matter present in the halos of these galaxies. Using these constraints, one can show that the halo dark matter cannot be some population of conventional astronomical objects and (most probably) cannot be a population of exotic non-interacting particles. We suggest that the halos can be regarded as large spatial fluctuations in a classic scalar field.

  17. Acoustics Local Area Network

    DTIC Science & Technology

    2013-01-31

    contract was to provide a shared computing i : resource - the acou tics local area network (ALAN) - to support ocean acoustic and related oceanographic...SECURITY CLASSIFICATION 20. UMITATION OF ABSTRACT OF REPORT: THIS PAGE OF ABSTRACT Unclassified I I ONRCtI COMPUTER V 10 11/94 STANDARD FORM 233 (REV 241) oo 0 90 " VLNV1LV HNO Og6OuLtOI, CT:tT 96/OT/0

  18. Localized solar collectors

    SciTech Connect

    Ghasemi, Hadi; Marconnet, Amy Marie; Chen, Gang; Ni, George Wei

    2016-10-04

    A localized heating structure, and method of forming same, for use in solar systems includes a thermally insulating layer having interconnected pores, a density of less than about 3000 kg/m.sup.3, and a hydrophilic surface, and an expanded carbon structure adjacent to the thermally insulating layer. The expanded carbon structure has a porosity of greater than about 80% and a hydrophilic surface.

  19. Enhanced local tomography

    DOEpatents

    Katsevich, Alexander J.; Ramm, Alexander G.

    1996-01-01

    Local tomography is enhanced to determine the location and value of a discontinuity between a first internal density of an object and a second density of a region within the object. A beam of radiation is directed in a predetermined pattern through the region of the object containing the discontinuity. Relative attenuation data of the beam is determined within the predetermined pattern having a first data component that includes attenuation data through the region. In a first method for evaluating the value of the discontinuity, the relative attenuation data is inputted to a local tomography function .function..sub..LAMBDA. to define the location S of the density discontinuity. The asymptotic behavior of .function..sub..LAMBDA. is determined in a neighborhood of S, and the value for the discontinuity is estimated from the asymptotic behavior of .function..sub..LAMBDA.. In a second method for evaluating the value of the discontinuity, a gradient value for a mollified local tomography function .gradient..function..sub..LAMBDA..epsilon. (x.sub.ij) is determined along the discontinuity; and the value of the jump of the density across the discontinuity curve (or surface) S is estimated from the gradient values.

  20. Simulating the local Universe

    NASA Astrophysics Data System (ADS)

    Sorce, J. G.

    2016-12-01

    In the local Universe, cosmic structures can be observed down to very small scales, scales on which the standard cosmological model might fail. Such detailed observations have to be compared with simulations in order to verify the predictions of different cosmological models. However, the cosmic variance can obscure the tests. More precisely, comparisons on a one-to-one basis are feasible only with simulations that look like the local Universe. Constrained by observed positions and peculiar velocities of galaxies, the simulations presented here reproduce locally the three-dimensional distribution of matter. Within a sphere of radius 100 hMpc, the observed nearby Large and Small Scale Structure is simulated with an accuracy of a few megaparsecs. These simulations include our nearest cluster neighbor, Virgo, allowing a detailed study of its formation history. It follows that the Virgo cluster has had a quiet merging history within the last seven gigayears. In the near future, zoom-in hydrodynamical simulations of the later will permit deeper comparisons with observations.

  1. Bursting with Geometry

    ERIC Educational Resources Information Center

    Cipoletti, Beth; Wilson, Nancy

    2009-01-01

    This article describes an activity that introduces the Lithuanian holiday tradition of decorating with straw ornaments in geometric shapes. By building a Lithuanian sunburst star with straws, students explore a number of geometric relationships and reinforce their mathematical vocabulary. It also provides an excellent foundation for a…

  2. Local Group Cosmology

    NASA Astrophysics Data System (ADS)

    Martínez-Delgado, David

    2013-11-01

    List of contributors; List of participants; Preface; Acknowledgments; Abbreviations; 1. The formation of the Milky Way in the CDM paradigm Ken Freeman; 2. Dark matter content and tidal effects in Local Group dwarf galaxies Steven R. Majewski; 3. Notes on the missing satellites problem James Bullock; 4. The Milky Way satellite galaxies Pavel Kroupa; 5. Stellar tidal streams Rodrigo Ibata; 6. Tutorial: the analysis of colour-magnitude diagrams David Valls-Gabaud; 7. Tutorial: modeling tidal streams using N-body simulations Jorge Peñarrubia.

  3. Local Allergic Rhinitis.

    PubMed

    Campo, Paloma; Salas, María; Blanca-López, Natalia; Rondón, Carmen

    2016-05-01

    This review focuses on local allergic rhinitis, a new phenotype of allergic rhinitis, commonly misdiagnosed as nonallergic rhinitis. It has gained attention over last decade and can affect patients from all countries, ethnic groups and ages, impairing their quality of life, and is frequently associated with conjunctivitis and asthma. Diagnosis is based on clinical history, the demonstration of a positive response to nasal allergen provocation test and/or the detection of nasal sIgE. A positive basophil activation test may support the diagnosis. Recent studies have demonstrated that allergen immunotherapy is an effective immune-modifying treatment, highlighting the importance of early diagnosis.

  4. Identification of mammalian orthologs using local synteny

    PubMed Central

    2009-01-01

    Background Accurate determination of orthology is central to comparative genomics. For vertebrates in particular, very large gene families, high rates of gene duplication and loss, multiple mechanisms of gene duplication, and high rates of retrotransposition all combine to make inference of orthology between genes difficult. Many methods have been developed to identify orthologous genes, mostly based upon analysis of the inferred protein sequence of the genes. More recently, methods have been proposed that use genomic context in addition to protein sequence to improve orthology assignment in vertebrates. Such methods have been most successfully implemented in fungal genomes and have long been used in prokaryotic genomes, where gene order is far less variable than in vertebrates. However, to our knowledge, no explicit comparison of synteny and sequence based definitions of orthology has been reported in vertebrates, or, more specifically, in mammals. Results We test a simple method for the measurement and utilization of gene order (local synteny) in the identification of mammalian orthologs by investigating the agreement between coding sequence based orthology (Inparanoid) and local synteny based orthology. In the 5 mammalian genomes studied, 93% of the sampled inter-species pairs were found to be concordant between the two orthology methods, illustrating that local synteny is a robust substitute to coding sequence for identifying orthologs. However, 7% of pairs were found to be discordant between local synteny and Inparanoid. These cases of discordance result from evolutionary events including retrotransposition and genome rearrangements. Conclusions By analyzing cases of discordance between local synteny and Inparanoid we show that local synteny can distinguish between true orthologs and recent retrogenes, can resolve ambiguous many-to-many orthology relationships into one-to-one ortholog pairs, and might be used to identify cases of non-orthologous gene

  5. Red Supergiants in the Local Group

    NASA Astrophysics Data System (ADS)

    Levesque, E. M.

    2013-05-01

    Galaxies in the Local Group span a factor of 15 in metallicity, ranging from the super-solar M 31 to the Wolf-Lundmark-Melotte (WLM) galaxy, which is the lowest-metallicity (0.1 Z⊙) Local Group galaxy currently forming stars. Studies of massive star populations across this broad range of environments have revealed important metal-licity-dependent evolutionary trends, allowing us to test the accuracy of stellar evolutionary tracks at these metallicities for the first time. The RSG population is particularly valuable as a key mass-losing phase of moderately massive stars and a source of core-collapse supernova progenitors. By reviewing recent work on the RSG populations in the Local Group, we are able to quantify limits on these stars' effective temperatures and masses and probe the relationship between RSG mass loss behaviors and host environments. Extragalactic surveys of RSGs have also revealed several unusual RSGs that display signs of unusual spectral variability and dust production, traits that may potentially also correlate with the stars' host environments. I will present some of the latest work that has advanced our understanding of RSGs in the Local Group, and consider the many new questions posed by our ever-evolving picture of these stars.

  6. 47 CFR 36.3 - Freezing of jurisdictional separations category relationships and/or allocation factors.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... category relationships for the acquiring carrier's post-transfer study area. (e) Any local exchange carrier... relationships and/or allocation factors. 36.3 Section 36.3 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... § 36.3 Freezing of jurisdictional separations category relationships and/or allocation factors....

  7. 47 CFR 36.3 - Freezing of jurisdictional separations category relationships and/or allocation factors.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... category relationships for the acquiring carrier's post-transfer study area. (e) Any local exchange carrier... relationships and/or allocation factors. 36.3 Section 36.3 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... § 36.3 Freezing of jurisdictional separations category relationships and/or allocation factors....

  8. Passive Acoustic Vessel Localization

    NASA Astrophysics Data System (ADS)

    Suwal, Pasang Sherpa

    This thesis investigates the development of a low-cost passive acoustic system for localizing moving vessels to monitor areas where human activities such as fishing, snorkeling and poaching are restricted. The system uses several off-the-shelf sensors with unsynchronized clocks where the Time Difference of Arrival (TDOA) or time delay is extracted by cross-correlation of the signal between paired sensors. The cross-correlation function uses phase correlation or Phase Transform (PHAT) which whitens the cross-spectrum in order to de-emphasize dominant frequency components. Using the locations of pairs of sensors as foci, hyperbolic equations can be defined using the time delay between them. With three or more sensors, multiple hyperbolic functions can be calculated which intersect at a unique point: the boat's location. It is also found that increasing separation distances between sensors decreased the correlation between the signals. However larger separation distances have better localization capability than with small distances. Experimental results from the Columbia and Willamette Rivers are presented to demonstrate performance.

  9. Draining the Local Void

    NASA Astrophysics Data System (ADS)

    Rizzi, Luca; Tully, R. Brent; Shaya, Edward J.; Kourkchi, Ehsan; Karachentsev, Igor D.

    2017-01-01

    Two galaxies that lie deep within the Local Void provide a test of the expectation that voids expand. The modest ({M}B∼ -14) HI bearing dwarf galaxies ALFAZOAJ1952+1428 and KK246 have been imaged with Hubble Space Telescope in order to study the stellar populations and determine distances from the luminosities of stars at the tip of the red giant branch. The mixed age systems have respective distances of 8.39 Mpc and 6.95 Mpc and inferred line-of-sight peculiar velocities of ‑114 km s‑1 and ‑66 km s‑1 toward us and away from the void center. These motions compound on the Milky Way motion of ∼230 km s‑1 away from the void. The orbits of the two galaxies are reasonably constrained by a numerical action model encompassing an extensive region that embraces the Local Void. It is unambiguously confirmed that these two void galaxies are moving away from the void center at several hundred km s‑1.

  10. Generalized local emission tomography

    DOEpatents

    Katsevich, Alexander J.

    1998-01-01

    Emission tomography enables locations and values of internal isotope density distributions to be determined from radiation emitted from the whole object. In the method for locating the values of discontinuities, the intensities of radiation emitted from either the whole object or a region of the object containing the discontinuities are inputted to a local tomography function .function..sub..LAMBDA..sup.(.PHI.) to define the location S of the isotope density discontinuity. The asymptotic behavior of .function..sub..LAMBDA..sup.(.PHI.) is determined in a neighborhood of S, and the value for the discontinuity is estimated from the asymptotic behavior of .function..sub..LAMBDA..sup.(.PHI.) knowing pointwise values of the attenuation coefficient within the object. In the method for determining the location of the discontinuity, the intensities of radiation emitted from an object are inputted to a local tomography function .function..sub..LAMBDA..sup.(.PHI.) to define the location S of the density discontinuity and the location .GAMMA. of the attenuation coefficient discontinuity. Pointwise values of the attenuation coefficient within the object need not be known in this case.

  11. Acoustic sniper localization system

    NASA Astrophysics Data System (ADS)

    Prado, Gervasio; Dhaliwal, Hardave; Martel, Philip O.

    1997-02-01

    Technologies for sniper localization have received increased attention in recent months as American forces have been deployed to various trouble spots around the world. Among the technologies considered for this task acoustics is a natural choice for various reasons. The acoustic signatures of gunshots are loud and distinctive, making them easy to detect even in high noise background environments. Acoustics provides a passive sensing technology with excellent range and non line of sight capabilities. Last but not least, an acoustic sniper location system can be built at a low cost with off the shelf components. Despite its many advantages, the performance of acoustic sensors can degrade under adverse propagation conditions. Localization accuracy, although good, is usually not accurate enough to pinpoint a sniper's location in some scenarios (for example which widow in a building or behind which tree in a grove). For these more demanding missions, the acoustic sensor can be used in conjunction with an infra red imaging system that detects the muzzle blast of the gun. The acoustic system can be used to cue the pointing system of the IR camera in the direction of the shot's source.

  12. Pattern Driven Stress Localization

    NASA Astrophysics Data System (ADS)

    Croll, Andrew; Crosby, Alfred

    2010-03-01

    The self-assembly of patterns from isotropic initial states is a major driver of modern soft-matter research. This avenue of study is directed by the desire to understand the complex physics of the varied structures found in Nature, and by technological interest in functional materials that may be derived through biomimicry. In this work we show how a simple striped phase can respond with significant complexity to an appropriately chosen perturbation. In particular, we show how a buckled elastic plate transitions into a state of stress localization using a simple, self-assembled variation in surface topography. The collection of topographic boundaries act in concert to change the state from isotropic sinusoidal wrinkles, to sharp folds or creases separated by relatively flat regions. By varying the size of the imposed topographic pattern or the wavelength of the wrinkles, we construct a state diagram of the system. The localized state has implications for both biological systems, and for the control of non-linear pattern formation.

  13. Locality and reality

    SciTech Connect

    Stapp, Henry P.

    1980-10-01

    Einstein's principle that no signal travels faster than suggests that observations in one spacetime region should not depend on whether or not a radioactive decay is detected in a spacelike separated region. This locality property is incompatible with the predictions of quantum theory, and this incompatibility holds independently of the questions of realism, objective reality, and hidden variables. It holds both in the pragmatic quantum theory of Bohr and in realistic frameworks. It is shown here to hold in a completed realistic quantum theory that reconciles Einstein's demand for a description of reality itself with Bohr's contention that quantum theory is complete. This completed realistic quantum theory has no hidden variables, and no objective reality in which observable attributes can become definite independently of observers. The, theory is described in some detail, with particular attention to those aspects related to the question of locality. This completed realistic quantum theory is in principle more comprehensive than Bohr.' s pragmatic quantum theory because it is not limited in principle by the requirement that the observed system be physically separated from the observing one. Applications are discussed.

  14. Local collaborations: development and implementation of Boston's bioterrorism surveillance system.

    PubMed

    McKenna, Verna B; Gunn, Julia E; Auerbach, John; Brinsfield, Kathryn H; Dyer, K Sophia; Barry, M Anita

    2003-01-01

    The Boston Public Health Commission developed and implemented an active surveillance system for bioterrorism and other infectious disease emergencies. A bioterrorism Surveillance Task Force was formed with representatives from local emergency medicine, infection control, infectious diseases, public health, and emergency medical services. These local agencies worked together to develop a reliable, easy to use electronic surveillance system. Collaboration at the local level and building on existing relationships is a key component of this system. Effective follow-up systems and technology back-up plans are essential. Improved communication networks and increased bioterrorism education for clinicians and the general public have also been achieved.

  15. All Holdings Are Local: Archivists and Local Government Archives

    ERIC Educational Resources Information Center

    James, Russell D.

    2004-01-01

    Archivists working in repositories that contain local government records play an integral role within the local community. Unlike their colleagues in state, regional, or national repositories, the local government archivist concentrates on a small geographic region and demonstrates knowledge of the politics, history, and socio-economics of the…

  16. THz Local Oscillator Sources

    NASA Astrophysics Data System (ADS)

    Mehdi, Imran; Schlecht, Erich; Chattopadhyay, Goutam; Siegel, Peter H.

    Most operational Submillimeter-wave radio telescopes, both space borne and ground based, employ local oscillator sources based on Gunn diodes followed by whisker contacted Schottky multipliers. Enough progress, however, has been made on a number of fronts to conclude that next generation of radio telescopes that become operational in the new Millennium will have a different local oscillator (LO) generation architecture. MMIC power amplifiers with impressive gain in the Ka- to-W band have enabled the use of microwave synthesizers which can then be actively multiplied to provide a frequency agile power source beyond 100 GHz. This medium power millimeter source can then be amplified to enable efficient pumping of follow-on balanced multiplier stages. Input power to the multipliers can be further enhanced by power combining to achieve close to half a Watt at W-band. An 800 GHz three-stage multiplier chain, implemented this way has demonstrated a peak output power of 1 mW. A second advance in LO generation lies in the Schottky diode varactor technology. Planar Schottky diode multipliers have now been demonstrated up to 1500 GHz and it can be assumed that most of the future multiplier chains will be based on these robust devices rather than the whisker contacted diode of the past. The ability to produce planar GaAs diode chips deep into the THz range, with submicron dimensions, has opened up a wide range of circuit design space which can be taken advantage of to improve efficiency, bandwidth, and power handling capability of the multipliers. A third breakthrough has been the demonstration of photonic based LO sources utilizing GaAs photomixers. These sources, though not yet implemented in robust space borne missions, offer a number of advantages over their electronic counterparts, including extremely broad tuning, fiber coupled components, and solid-state implementation. Another development, which holds some promise, is the use of micro-machining technology to implement

  17. Optical closure of parameterized bio-optical relationships

    NASA Astrophysics Data System (ADS)

    He, Shuangyan; Fischer, Jürgen; Schaale, Michael; He, Ming-xia

    2014-03-01

    An optical closure study on bio-optical relationships was carried out using radiative transfer model matrix operator method developed by Freie Universität Berlin. As a case study, the optical closure of bio-optical relationships empirically parameterized with in situ data for the East China Sea was examined. Remote-sensing reflectance ( R rs) was computed from the inherent optical properties predicted by these biooptical relationships and compared with published in situ data. It was found that the simulated R rs was overestimated for turbid water. To achieve optical closure, bio-optical relationships for absorption and scattering coefficients for suspended particulate matter were adjusted. Furthermore, the results show that the Fournier and Forand phase functions obtained from the adjusted relationships perform better than the Petzold phase function. Therefore, before bio-optical relationships are used for a local sea area, the optical closure should be examined.

  18. Global and Local Collaborators: A Study of Scientific Collaboration.

    ERIC Educational Resources Information Center

    Pao, Miranda Lee

    1992-01-01

    Describes an empirical study that was conducted to examine the relationship among scientific co-authorship (i.e., collaboration), research funding, and productivity. Bibliographic records from the MEDLINE database that used the subject heading for schistosomiasis are analyzed, global and local collaborators are discussed, and scientific…

  19. Local Area Networks: Effective Tools for Special Libraries.

    ERIC Educational Resources Information Center

    Hoehl, Susan B.

    1988-01-01

    Examines technological changes in the local area network (LAN) of the Health Sciences Library of Allegheny General Hospital during three years of operation and describes the resulting evolution of staff, services, network requirements, budget, and external relationships of the library. LAN expenditures over four years are shown. (1 reference) (MES)

  20. Stable local oscillator microcircuit.

    SciTech Connect

    Brocato, Robert Wesley

    2006-10-01

    This report gives a description of the development of a Stable Local Oscillator (StaLO) Microcircuit. The StaLO accepts a 100MHz input signal and produces output signals at 1.2, 3.3, and 3.6 GHz. The circuit is built as a multi-chip module (MCM), since it makes use of integrated circuit technologies in silicon and lithium niobate as well as discrete passive components. The StaLO uses a comb generator followed by surface acoustic wave (SAW) filters. The comb generator creates a set of harmonic components of the 100MHz input signal. The SAW filters are narrow bandpass filters that are used to select the desired component and reject all others. The resulting circuit has very low sideband power levels and low phase noise (both less than -40dBc) that is limited primarily by the phase noise level of the input signal.

  1. Headphone localization of speech

    NASA Technical Reports Server (NTRS)

    Begault, Durand R.; Wenzel, Elizabeth M.

    1993-01-01

    Three-dimensional acoustic display systems have recently been developed that synthesize virtual sound sources over headphones based on filtering by head-related transfer functions (HRTFs), the direction-dependent spectral changes caused primarily by the pinnae. In this study, 11 inexperienced subjects judged the apparent spatial location of headphone-presented speech stimuli filtered with nonindividualized HRTFs. About half of the subjects 'pulled' their judgments toward either the median or the lateral-vertical planes, and estimates were almost always elevated. Individual differences were pronounced for the distance judgments; 15 to 46 percent of stimuli were heard inside the head, with the shortest estimates near the median plane. The results suggest that most listeners can obtain useful azimuth information from speech stimuli filtered by nonindividualized HRTFs. Measurements of localization error and reversal rates are comparable with a previous study that used broadband noise stimuli.

  2. Local control stations

    SciTech Connect

    Brown, W.S.; Higgins, J.C.; Wachtel, J.A.

    1993-05-01

    This paper describes research concerning the effects of human engineering design at local control stations (i.e., operator interfaces located outside the control room) on human performance and plant safety. The research considered both multifunction panels (e.g. remote shutdown panels) as well as single-function interfaces (e.g., valves, breakers, gauges, etc.). Changes in performance shaping factors associated with variations in human engineering at LCSs were estimated based on expert opinion. By means of a scaling procedure, these estimates were used to modify the human error probabilities in a PRA model, which was then employed to generate estimates of plant risk and scoping-level value/impact ratios for various human engineering upgrades. Recent documentation of human engineering deficiencies at single-function LCSs was also reviewed, and an assessment of the current status of LCSs with respect to human engineering was conducted.

  3. Headphone localization of speech.

    PubMed

    Begault, D R; Wenzel, E M

    1993-06-01

    Three-dimensional acoustic display systems have recently been developed that synthesize virtual sound sources over headphones based on filtering by head-related transfer functions (HRTFs), the direction-dependent spectral changes caused primarily by the pinnae. In this study 11 inexperienced subjects judged the apparent spatial location of headphone-presented speech stimuli filtered with non-individualized HRTFs. About half of the subjects "pulled" their judgments toward either the median or the lateral-vertical planes, and estimates were almost always elevated. Individual differences were pronounced for the distance judgments; 15% to 46% of stimuli were heard inside the head, with the shortest estimates near the median plane. The results suggest that most listeners can obtain useful azimuth information from speech stimuli filtered by nonindividualized HRTFs. Measurements of localization error and reversal rates are comparable with a previous study that used broadband noise stimuli.

  4. Localized wave pulse experiments

    SciTech Connect

    Chambers, D L; Henderson, T L; Krueger, K L; Lewis, D K; Zilkowski, R N

    1999-06-01

    The Localized Wave project of the Strategic System Support Program has recently finished an experiment in cooperation with the Advanced SONAR group of the Applied Research Laboratory of the University of Texas at Austin. The purpose of the experiment was three-fold. They wanted to see if (1) the LW pulse could propagate over significant distances, to see if (2) a new type of array and drive system specifically designed for the pulse would increase efficiency over single frequency tone bursts, and to see if (3) the complexity of our 24 channel drivers resulted in better efficiency than a single equivalent pulse driving a piston. In the experiment, several LW pulses were launched from the Lake Travis facility and propagated over distances of either 100 feet or 600 feet, through a thermocline for the 600 foot measurements. The results show conclusively that the Localized Wave will propagate past the near field distance. The LW pulses resulted in extremely broad frequency band width pulses with narrow spatial beam patterns and unmeasurable side lobes. Their array gain was better than most tone bursts and further, were better than their equivalent piston pulses. This marks the first test of several Low Diffraction beams against their equivalent piston pulses, as well as the first propagation of LW pulses over appreciable distances. The LW pulse is now proven a useful tool in open water, rather than a laboratory curiosity. The experimental system and array were built by ARL, and the experiments were conducted by ARL staff on their standard test range. The 600 feet measurements were made at the farthest extent of that range.

  5. Population structure with localized haplotype clusters.

    PubMed

    Browning, Sharon R; Weir, Bruce S

    2010-08-01

    We propose a multilocus version of F(ST) and a measure of haplotype diversity using localized haplotype clusters. Specifically, we use haplotype clusters identified with BEAGLE, which is a program implementing a hidden Markov model for localized haplotype clustering and performing several functions including inference of haplotype phase. We apply this methodology to HapMap phase 3 data. With this haplotype-cluster approach, African populations have highest diversity and lowest divergence from the ancestral population, East Asian populations have lowest diversity and highest divergence, and other populations (European, Indian, and Mexican) have intermediate levels of diversity and divergence. These relationships accord with expectation based on other studies and accepted models of human history. In contrast, the population-specific F(ST) estimates obtained directly from single-nucleotide polymorphisms (SNPs) do not reflect such expected relationships. We show that ascertainment bias of SNPs has less impact on the proposed haplotype-cluster-based F(ST) than on the SNP-based version, which provides a potential explanation for these results. Thus, these new measures of F(ST) and haplotype-cluster diversity provide an important new tool for population genetic analysis of high-density SNP data.

  6. Design of a Localized Fluidization Burrowing Robot

    NASA Astrophysics Data System (ADS)

    Dorsch, Daniel; Winter, Amos

    2014-11-01

    This presentation will focus on the critical fluid and granular mechanics principles that drove the design of RoboClam 2.0, a self-actuated, radially expanding underwater burrowing device. RoboClam 2.0 was inspired by the Atlantic razor clam, Ensis directus, which burrows by contracting its valves and fluidizing the surrounding soil to reduce burrowing drag. This contraction results in a localized fluidized region occurring 1-5 body radii away from the animal. Moving through a fluidized, rather than static, soil requires energy that scales linearly with depth, rather than depth squared. In addition to providing an advantage for the animal, localized fluidization may yield significant value to engineering applications such as subsea robot anchoring and pipe installation. RoboClam 2.0 is sized to be an anchoring platform for autonomous underwater vehicles. We will present the scaling relationships that can be used to design RoboClam derivatives for different size scales and applications. The critical speed, displacement and force with which the device must contract to create fluidization are calculated based on soil parameters. These parametric relationships allow for choosing actuators of appropriate size and power output for desired burrowing performance.

  7. Estimation of local spatial scale

    NASA Technical Reports Server (NTRS)

    Watson, Andrew B.

    1987-01-01

    The concept of local scale asserts that for a given class of psychophysical measurements, performance at any two visual field locations is equated by magnifying the targets by the local scale associated with each location. Local scale has been hypothesized to be equal to cortical magnification or alternatively to the linear density of receptors or ganglion cells. Here, it is shown that it is possible to estimate local scale without prior knowledge about the scale or its physiological basis.

  8. Contact angle and local wetting at contact line.

    PubMed

    Li, Ri; Shan, Yanguang

    2012-11-06

    This theoretical study was motivated by recent experiments and theoretical work that had suggested the dependence of the static contact angle on the local wetting at the triple-phase contact line. We revisit this topic because the static contact angle as a local wetting parameter is still not widely understood and clearly known. To further clarify the relationship of the static contact angle with wetting, two approaches are applied to derive a general equation for the static contact angle of a droplet on a composite surface composed of heterogeneous components. A global approach based on the free surface energy of a thermodynamic system containing the droplet and solid surface shows the static contact angle as a function of local surface chemistry and local wetting state at the contact line. A local approach, in which only local forces acting on the contact line are considered, results in the same equation. The fact that the local approach agrees with the global approach further demonstrates the static contact angle as a local wetting parameter. Additionally, the study also suggests that the wetting described by the Wenzel and Cassie equations is also the local wetting of the contact line rather than the global wetting of the droplet.

  9. Multi-organ localization with cascaded global-to-local regression and shape prior.

    PubMed

    Gauriau, Romane; Cuingnet, Rémi; Lesage, David; Bloch, Isabelle

    2015-07-01

    We propose a method for fast, accurate and robust localization of several organs in medical images. We generalize the global-to-local cascade of regression random forest to multiple organs. A first regressor encodes the global relationships between organs, learning simultaneously all organs parameters. Then subsequent regressors refine the localization of each organ locally and independently for improved accuracy. By combining the regression vote distribution and the organ shape prior (through probabilistic atlas representation) we compute confidence maps that are organ-dedicated probability maps. They are used within the cascade itself, to better select the test voxels for the second set of regressors, and to provide richer information than the classical bounding boxes result thanks to the shape prior. We propose an extensive study of the different learning and testing parameters, showing both their robustness to reasonable perturbations and their influence on the final algorithm accuracy. Finally we demonstrate the robustness and accuracy of our approach by evaluating the localization of six abdominal organs (liver, two kidneys, spleen, gallbladder and stomach) on a large and diverse database of 130 CT volumes. Moreover, the comparison of our results with two existing methods shows significant improvements brought by our approach and our deep understanding and optimization of the parameters.

  10. Federal, State, and Local regulations

    SciTech Connect

    Kelly, J.M.; Brandenburg, B.L. )

    1991-08-01

    This article is a review of federal, state, and local regulations pertinent treatment of leachate from hazardous materials landfills in California. The topics covered include under federal regulations: pretreatment, whole-effluent toxicity, hazardous waste regulation; under state regulations: hazardous waste regulations, air toxics, environmental quality act; under local regulations: local limits, toxicity-regional water quality board, air emissions and district code.

  11. Local Government: The Learning Laboratory.

    ERIC Educational Resources Information Center

    Degelman, Charles, Ed.

    2001-01-01

    This issue of "Service-Learning Network" looks at the ways that service learning can transform local government into a learning laboratory for civic education. The first article, "Creating the Missing Link: Local Government, Service Learning, and Civic Education" (Todd Clark), introduces the issue. "Service Learning and Local Government" (Ann…

  12. Cadmium and zinc relationships.

    PubMed

    Elinder, C G; Piscator, M

    1978-08-01

    Cadmium and zinc concentrations in kidney and liver have been measured under different exposure situations in different species including man. The results show that zinc increases almost equimolarly with cadmium in kidney after long-term low-level exposure to cadmium, e.g., in man, horse, pig, and lamb. In contrast, the increase of zinc follows that of cadmium to only a limited extent, e.g., in guinea pig, rabbit, rat, mouse, and chicks. In liver, the cadmium--zinc relationship seems to be reversed in such a way that zinc increases with cadmium more markedly in laboratory animals than in higher mammals. These differences between cadmium and zinc relationships in humans and large farm animals and those in commonly used laboratory animals must be considered carefully before experimental data on cadmium and zinc relationships in laboratory animals can be extrapolated to humans.

  13. Resolution limits of ultrafast ultrasound localization microscopy

    NASA Astrophysics Data System (ADS)

    Desailly, Yann; Pierre, Juliette; Couture, Olivier; Tanter, Mickael

    2015-11-01

    As in other imaging methods based on waves, the resolution of ultrasound imaging is limited by the wavelength. However, the diffraction-limit can be overcome by super-localizing single events from isolated sources. In recent years, we developed plane-wave ultrasound allowing frame rates up to 20 000 fps. Ultrafast processes such as rapid movement or disruption of ultrasound contrast agents (UCA) can thus be monitored, providing us with distinct punctual sources that could be localized beyond the diffraction limit. We previously showed experimentally that resolutions beyond λ/10 can be reached in ultrafast ultrasound localization microscopy (uULM) using a 128 transducer matrix in reception. Higher resolutions are theoretically achievable and the aim of this study is to predict the maximum resolution in uULM with respect to acquisition parameters (frequency, transducer geometry, sampling electronics). The accuracy of uULM is the error on the localization of a bubble, considered a point-source in a homogeneous medium. The proposed model consists in two steps: determining the timing accuracy of the microbubble echo in radiofrequency data, then transferring this time accuracy into spatial accuracy. The simplified model predicts a maximum resolution of 40 μm for a 1.75 MHz transducer matrix composed of two rows of 64 elements. Experimental confirmation of the model was performed by flowing microbubbles within a 60 μm microfluidic channel and localizing their blinking under ultrafast imaging (500 Hz frame rate). The experimental resolution, determined as the standard deviation in the positioning of the microbubbles, was predicted within 6 μm (13%) of the theoretical values and followed the analytical relationship with respect to the number of elements and depth. Understanding the underlying physical principles determining the resolution of superlocalization will allow the optimization of the imaging setup for each organ. Ultimately, accuracies better than the size

  14. Building mentoring relationships.

    PubMed

    Hamilton, Stephen F; Hamilton, Mary Agnes

    2010-01-01

    This article is the first of three brief commentaries on this volume. The authors are highly influential pioneers in the study of youth mentoring relationships, and their contributions helped shape the focus of the conceptual framework featured in the opening article by Karcher and Nakkula. Their commentary sheds light on the history of key issues presented in this volume, including the origins of their early work on instrumentality--goal-focused orientation--and relationship building in youth mentoring, and links those efforts to the contributions presented in this special issue.

  15. Impact of an Intimate Relationships Class on Unrealistic Relationship Beliefs

    ERIC Educational Resources Information Center

    Bass, Brenda L.; Drake, Teske R.; Linney, Kirsten D.

    2007-01-01

    Unrealistic relationship beliefs have been shown to be related to lower levels of relationship satisfaction. Yet, young adults often hold unrealistic or irrational beliefs about intimate relationships. The purpose of this study was to assess the effectiveness of an intimate relationships course in reducing young adults' irrational relationship…

  16. Localization algorithm and error analysis for micro radio-localizer

    NASA Astrophysics Data System (ADS)

    Li, Xudong; Wang, Xiaohao; Li, Qiang; Zhao, Huijie

    2006-11-01

    After more than ten years' research efforts on the Micro Aerial Vehicle (MAV) since it was proposed in 1990s, the stable flying platform has been matured. The next reasonable goal is to implement more practical applications for MAVs. Equipped with a micro radio-localizer, MAVs have the ability of localizing a target that transmitting radio signals, and further can be a novel promising Anti-Radiation device. A micro radio-localizer prototype and its localization principle and localization algorithm are proposed. The error analysis of the algorithm is also discussed. On the basis of the comparison of the often-used radio localization method, considering the MAVs' inherent limitation on the dimension of the antennas, a signal intensity and guidance information based localization method is proposed. Under the assumption that the electromagnetic wave obeys the free-space spreading model and the signal's power keeps unchanged, the measuring equations under different target motions are established. Localization algorithm is derived. The determination of several factors such as the number of measuring positions, numerical solving method and initial solution is discussed. Error analysis of the localization algorithm is also proposed by utilizing error analysis theory. A radio-localizer prototype is developed and experiment results are shown as well.

  17. Local Universe Dwarf Galaxies

    NASA Astrophysics Data System (ADS)

    Carignan, Claude

    2015-08-01

    One of the outstanding problems in cosmology is addressing the "small-scale crisis" and understanding structure formation at the smallest scales. Standard Lambda Cold Dark Matter cosmological simulations of Milky Way-size DM halos predict many more DM sub-halos than the number of dwarf galaxies observed. This is the so-called Missing Satellites Problem. The most popular interpretation of the Missing Satellites Problem is that the smallest dark matter halos in the universe are extremely inefficient at forming stars. The virialized extent of the Milky Way's halo should contain ~500 satellites, while only ˜100 satellites and dwarfs are observed in the whole Local Group. Despite the large amount of theoretical work and new optical observations, the discrepancy, even if reduced, still persists between observations and hierarchical models, regardless of the model parameters. It may be possible to find those isolated ultra-faint missing dwarf galaxies via their neutral gas component, which is one of the goals we are pursuing with the SKA precursor KAT-7 in South Africa, and soon with the SKA pathfinder MeerKAT.

  18. Local slope stability analysis

    NASA Astrophysics Data System (ADS)

    Hattendorf, I.; Hergarten, St.; Neugebauer, H. J.

    Mass movements under the influence of gravity occur as result of diverse disturbing and destabilizing processes, for example of climatic or anthropological origin. The stability of slopes is mainly determined by the geometry of the land-surface and designated slip-horizon. Further contributions are supplied by the pore water pressure, cohesion and friction. All relevant factors have to be integrated in a slope stability model, either by measurements and estimations (like phenomenological laws) or derived from physical equations. As result of stability calculations, it's suitable to introduce an expectation value, the factor-of-safety, for the slip-risk. Here, we present a model based on coupled physical equations to simulate hardly measurable phenomenons, like lateral forces and fluid flow. For the displacements of the soil-matrix we use a modified poroelasticity-equation with a Biot-coupling (Biot 1941) for the water pressure. Latter is described by a generalized Boussinesq equation for saturated-unsaturated porous media (Blendinger 1998). One aim of the calculations is to improve the knowledge about stability-distributions and their temporal variations. This requires the introduction of a local factor-of-safety which is the main difference to common stability models with global stability estimations. The reduction of immediate danger is still the emergent task of the most slope and landslide investigations, but this model is also useful with respect to understand the governing processes of landform evolution.

  19. Local positioning system

    SciTech Connect

    Kyker, R.

    1995-07-25

    Navigation systems have been vital to transportation ever since man took to the air and sea. Early navigation systems utilized the sextant to navigate by starlight as well as the magnetic needle compass. As electronics and communication technologies improved, inertial navigation systems were developed for use in ships and missile delivery. These systems consisted of electronic compasses, gyro-compasses, accelerometers, and various other sensors. Recently, systems such as LORAN and the Global Positioning System (GPS) have utilized the properties of radio wave propagation to triangulate position. The Local Positioning System (LPS), described in this paper, is an implementation of a limited inertial navigation system designed to be used on a bicycle. LPS displays a cyclist`s current position relative to a starting location. This information is displayed in Cartesian-like coordinates. To accomplish this, LPS relies upon two sensors, an electronic compass sensor and a distance sensor. The compass sensor provides directional information while the distance sensor provides the distance traveled. This information yields a distance vector for each point in time which when summed produces the cyclist`s current position. LPS is microprocessor controlled and is designed for a range of less than 90 miles.

  20. Impact of Local Sensors

    NASA Technical Reports Server (NTRS)

    Watson, Leela R.; Bauman, William H., III

    2008-01-01

    Forecasters at the 45th Weather Squadron (45 WS) use observations from the Kennedy Space Center (KSC) and Cape Canaveral Air Force Station (CCAFS) wind tower network and the CCAFS (XMR) daily rawinsonde observations (RAOB) to issue and verify wind advisories and warnings for operations. These observations are also used by the National Weather Service (NWS) Spaceflight Meteorology Group (SMG) in Houston, Texas and the NWS Melbourne, Florida (NWS MLB) to initialize their locally-run mesoscale models. In addition, SMG uses these observations to support shuttle landings at the Shuttle Landing Facility (SLF). Due to impending budget cuts, some or all of the KSC/CCAFS wind towers on the east-central Florida mainland and the XMR RAOBs may be eliminated. The locations of the mainland towers and XMR RAOB site are shown in Figure I. The loss of these data may impact the forecast capability of the 45 WS, SMG and NWS MLB. The AMU was tasked to conduct an objective independent modeling study to help determine how important these observations are to the accuracy of the model output used by the forecasters. To accomplish this, the Applied Meteorology Unit (AMU) performed a sensitivity study using the Weather Research and Forecasting (WRF) model initialized with and without KSC/CCAFS wind tower and XMR RAOB data.

  1. Transcontinental local area network

    NASA Astrophysics Data System (ADS)

    Hunt, Gareth

    2000-06-01

    The National Radio Astronomy Observatory (NRAO) has facilities at 17 different locations scattered throughout the USA. These vary in size from the major laboratories occupied by research and support staff to the ten individual antennas of the Very Long Baseline Array. As is typical in astronomy, many sites are in remote locations, which are not well served with modern communication capabilities. Until 1996, the NRAO's internal network was achieved via the Internet; most sites simply had a local port to the Internet and the traffic was routed tortuously to the other locations. The burgeoning demand for Internet bandwidth was (and still is) growing faster than the services could be enhanced, and this led to intolerably slow response times and unacceptably low achieved data rates. To solve this problem, the NRAO acquired a frame relay intranet from AT&T to connect ten of its locations. The operating cost is approximately the same as the multiple Internet connections, but with vastly improved throughput and reliability. Recently, the access to the four major sites has been upgraded to support video conferencing.

  2. Local load shedding

    SciTech Connect

    Adibi, M.M.; Thorne, D.K. )

    1988-08-01

    Equipment overloads in an underground transmission network are caused by unscheduled outages. Repairs or replacements of damaged cables and/or transformers in urban areas are inherently difficult and time-consuming. Therefore, for overloads greatly in excess of short-time ratings, speed of load shedding is of paramount importance. Under such conditions, the system operator is faced with: recognizing the problem, determining the course of action and shedding the correct amount of load at the right locations. These tasks are difficult to perform, particularly under pressure of time. Reliance on pre-specified load shedding lists is not satisfactory since the load shedding lists do not necessarily match the amounts and locations of the required loads to be shed. Clearly, there has been a need for a local load shedding scheme, which in the first order of importance, would relieve the overloaded equipment within the time limits imposed by the equipment short-time ratings and in the second order of importance, would ''minimize'' the amount of load to be curtailed. This paper describes an approach which meets the dual objective, providing a practical solution to a difficult engineering/operating problem.

  3. Towards Typology of Stakeholders: A Case of Lithuanian Higher Education

    ERIC Educational Resources Information Center

    Švaikauskiene, Simona; Mikulskiene, Birute

    2017-01-01

    The purpose of this paper is to explore internal management, advocacy and partnerships of interest groups with the aim of representing their interests in public policy formation with a view to developing a stakeholder typology. This qualitative study involves eight in-depth, semi-structured interviews with representatives from stakeholder…

  4. Links between accidents and lifestyle factors among Lithuanian schoolchildren.

    PubMed

    Starkuviene, Skirmante; Zaborskis, Apolinaras

    2005-01-01

    The aim of the study was to evaluate associations of some lifestyle factors with injuries among schoolchildren. Analysis was performed using data from the survey conducted in 2002 according to the methods of World Health Organization Cross-National Study on Health Behavior in School-Aged Children (HBSC). Using stratified random sampling, the representative sample of 5645 schoolchildren aged 11, 13, and 15 years from 104 schools of Lithuania was drawn and surveyed. Associations between potential risk factors and injuries among schoolchildren were evaluated calculating odds ratio and its 95% confidence intervals. For the evaluation of the impact of explanatory variables on analyzed event, logistic regression analysis was performed. Behavioral, psychological, and social integration factors were associated with the risk to sustain injuries among school-aged children. The impact of these factors varied within subgroups of schoolchildren by grade and sex. The most significant factors were: risk-taking behavior (smoking, alcohol and drug consumption, premature sexual activity), frequent participation in sport activities, involvement in physical fight, longer time spent away from home with friends, experienced bullying, poor self-assessed health and academic achievement, unhappiness, feeling unsafe at school, and high suicidal risk. Analysis failed to identify an expected association between lower socio-economic status and risk for injury. Integrated approach to injury etiology is essential in planning injury prevention and safety promotion activities among schoolchildren, paying particular attention to lifestyle factors, which can have the potential influence on risk to sustain injuries.

  5. Management of pharmaceutical substances in the environment: Lithuanian case study.

    PubMed

    Baranauskaitė-Fedorova, Inga; Dvarionienė, Jolanta; Nikiforov, Vladimir A

    2016-09-01

    Investigation on the sources, discharges and related risks for the environment of the pharmaceutical substance (PhS) diclofenac (DCF) was performed in Lithuania, a country of the Baltic Sea region, for the first time. The investigation only refers to DCF as a PhS for human use; emissions from animal husbandry were not considered. In the first stage of the research, the main sources and pathways of DCF via substance flow analysis were identified within the country. During the second stage, DCF flows along the wastewater treatment plants (WWTPs) in two different cities were measured in order to assess the current levels of pharmaceutical residues in the environment. Furthermore, environmental risk assessment was carried out by taking into account the parameters of consumption data and elimination rate in WWTPs. Then, the assessment of different technical and managerial removal approaches was accomplished in an environmental management model of wastewater containing PhS, based on the framework of environmental systems theory.

  6. Master Study Programmes Orientation and Curricula Inconsistency in Lithuanian Universities

    ERIC Educational Resources Information Center

    Lauzackas, Rimantas; Rackauskaite, Aiste; Jaskauskaite, Daiva

    2004-01-01

    When independence was restored in Lithuania, a single-stage higher education system that had existed hitherto was reorganised into a multi-stage system with Bachelor, Master and Doctoral programme studies. The analysis of Master studies, as a new and atypical phenomenon in Lithuania, highlights the discrepancies between Master programme curricula…

  7. A Case Study of a Lithuanian Foster Family

    ERIC Educational Resources Information Center

    Bankauskiene, Nijole; Staskeviciene, Vilma

    2005-01-01

    The authors discuss the problems of children's foster care in Lithuania in the context of European dimensions. The article consists of two parts. The first part presents the main changes in the children's care system in Lithuania. The first part reveals the discussion of the paradigm of children's foster care in both the Western and Lithuanian…

  8. Social Relationships and Health

    ERIC Educational Resources Information Center

    Cohen, Sheldon

    2004-01-01

    The author discusses 3 variables that assess different aspects of social relationships-social support, social integration, and negative interaction. The author argues that all 3 are associated with health outcomes, that these variables each influence health through different mechanisms, and that associations between these variables and health are…

  9. Snooping in Romantic Relationships

    ERIC Educational Resources Information Center

    Derby, Kelly; Knox, David; Easterling, Beth

    2012-01-01

    A 42 item Internet questionnaire was completed by 268 undergraduates at a large southeastern university to assess the frequency, motivations, and outcome of snooping in romantic relationships. Almost two thirds (66%) reported that they had engaged in snooping behavior, most often when the partner was taking a shower. Primary motives were…

  10. Customer Relationship Management.

    ERIC Educational Resources Information Center

    Fayerman, Michael

    2002-01-01

    Presents an approach increasingly employed by businesses to track and respond to their customers to provide better and faster services: customer relationship management. Discusses its applicability to the operations of higher education and institutional research and the role it plays in the knowledge management framework. (EV)

  11. Exploring and Understanding Relationships

    ERIC Educational Resources Information Center

    Durland, Maryann M.

    2005-01-01

    Although the process of doing social network analysis (SNA) is similar to traditional research and evaluation design, it is in the details that the two traditions diverge. This article describes two areas of differences: (1) the framework for doing SNA; and (2) data collection, analysis, and specific measures. SNA is about relationships and how to…

  12. A Working Relationship

    ERIC Educational Resources Information Center

    Fogg, Piper

    2006-01-01

    Bad relationships between a college board and its faculty can lead to erosion of the board's authority, faculty votes of no confidence, and general institutional instability. However, institutions like Randolph-Macon College are finding ways to improve the lack of understanding and sympathy between faculty members and trustees.

  13. Parental Relationships and Homosexuality

    ERIC Educational Resources Information Center

    Evans, Ray B.

    1971-01-01

    Confirmed is Bieber's finding (1962) that childhood parental relationships of homosexual men are less desirable than those of heterosexual men. However, while parental impact on children may be greater than the other way around, child impact on the parent probably determines parental attitudes toward that child. (CJ)

  14. Local tsunamis and earthquake source parameters

    USGS Publications Warehouse

    Geist, Eric L.; Dmowska, Renata; Saltzman, Barry

    1999-01-01

    This chapter establishes the relationship among earthquake source parameters and the generation, propagation, and run-up of local tsunamis. In general terms, displacement of the seafloor during the earthquake rupture is modeled using the elastic dislocation theory for which the displacement field is dependent on the slip distribution, fault geometry, and the elastic response and properties of the medium. Specifically, nonlinear long-wave theory governs the propagation and run-up of tsunamis. A parametric study is devised to examine the relative importance of individual earthquake source parameters on local tsunamis, because the physics that describes tsunamis from generation through run-up is complex. Analysis of the source parameters of various tsunamigenic earthquakes have indicated that the details of the earthquake source, namely, nonuniform distribution of slip along the fault plane, have a significant effect on the local tsunami run-up. Numerical methods have been developed to address the realistic bathymetric and shoreline conditions. The accuracy of determining the run-up on shore is directly dependent on the source parameters of the earthquake, which provide the initial conditions used for the hydrodynamic models.

  15. Global Response to Local Ionospheric Mass Ejection

    NASA Technical Reports Server (NTRS)

    Moore, T. E.; Fok, M.-C.; Delcourt, D. C.; Slinker, S. P.; Fedder, J. A.

    2010-01-01

    We revisit a reported "Ionospheric Mass Ejection" using prior event observations to guide a global simulation of local ionospheric outflows, global magnetospheric circulation, and plasma sheet pressurization, and comparing our results with the observed global response. Our simulation framework is based on test particle motions in the Lyon-Fedder-Mobarry (LFM) global circulation model electromagnetic fields. The inner magnetosphere is simulated with the Comprehensive Ring Current Model (CRCM) of Fok and Wolf, driven by the transpolar potential developed by the LFM magnetosphere, and includes an embedded plasmaspheric simulation. Global circulation is stimulated using the observed solar wind conditions for the period 24-25 Sept 1998. This period begins with the arrival of a Coronal Mass Ejection, initially with northward, but later with southward interplanetary magnetic field. Test particles are launched from the ionosphere with fluxes specified by local empirical relationships of outflow to electrodynamic and particle precipitation imposed by the MIlD simulation. Particles are tracked until they are lost from the system downstream or into the atmosphere, using the full equations of motion. Results are compared with the observed ring current and a simulation of polar and auroral wind outflows driven globally by solar wind dynamic pressure. We find good quantitative agreement with the observed ring current, and reasonable qualitative agreement with earlier simulation results, suggesting that the solar wind driven global simulation generates realistic energy dissipation in the ionosphere and that the Strangeway relations provide a realistic local outflow description.

  16. Local energy landscape in a simple liquid

    DOE PAGES

    Iwashita, T.; Egami, Takeshi

    2014-11-26

    It is difficult to relate the properties of liquids and glasses directly to their structure because of complexity in the structure that defies precise definition. The potential energy landscape (PEL) approach is a very insightful way to conceptualize the structure-property relationship in liquids and glasses, particularly the effect of temperature and history. However, because of the highly multidimensional nature of the PEL it is hard to determine, or even visualize, the actual details of the energy landscape. In this article we introduce a modified concept of the local energy landscape (LEL), which is limited in phase space, and demonstrate itsmore » usefulness using molecular dynamics simulation on a simple liquid at high temperatures. The local energy landscape is given as a function of the local coordination number, the number of the nearest-neighbor atoms. The excitation in the LEL corresponds to the so-called β-relaxation process. The LEL offers a simple but useful starting point to discuss complex phenomena in liquids and glasses.« less

  17. Local energy landscape in a simple liquid

    SciTech Connect

    Iwashita, T.; Egami, Takeshi

    2014-11-26

    It is difficult to relate the properties of liquids and glasses directly to their structure because of complexity in the structure that defies precise definition. The potential energy landscape (PEL) approach is a very insightful way to conceptualize the structure-property relationship in liquids and glasses, particularly the effect of temperature and history. However, because of the highly multidimensional nature of the PEL it is hard to determine, or even visualize, the actual details of the energy landscape. In this article we introduce a modified concept of the local energy landscape (LEL), which is limited in phase space, and demonstrate its usefulness using molecular dynamics simulation on a simple liquid at high temperatures. The local energy landscape is given as a function of the local coordination number, the number of the nearest-neighbor atoms. The excitation in the LEL corresponds to the so-called β-relaxation process. The LEL offers a simple but useful starting point to discuss complex phenomena in liquids and glasses.

  18. The relationship between playing computer or video games with mental health and social relationships among students in guidance schools, Kermanshah.

    PubMed

    Reshadat, S; Ghasemi, S R; Ahmadian, M; RajabiGilan, N

    2014-01-09

    Computer or video games are a popular recreational activity and playing them may constitute a large part of leisure time. This cross-sectional study aimed to evaluate the relationship between playing computer or video games with mental health and social relationships among students in guidance schools in Kermanshah, Islamic Republic of Iran, in 2012. Our total sample was 573 students and our tool was the General Health Questionnaire (GHQ-28) and social relationships questionnaires. Survey respondents reported spending an average of 71.07 (SD 72.1) min/day on computer or video games. There was a significant relationship between time spent playing games and general mental health (P < 0.04) and depression (P < 0.03). There was also a significant difference between playing and not playing computer or video games with social relationships and their subscales, including trans-local relationships (P < 0.0001) and association relationships (P < 0.01) among all participants. There was also a significant relationship between social relationships and time spent playing games (P < 0.02) and its dimensions, except for family relationships.

  19. All strategy is local.

    PubMed

    Greenwald, Bruce; Kahn, Judd

    2005-09-01

    The aim of strategy is to master a market environment by understanding and anticipating the actions of other economic agents, especially competitors. A firm that has some sort of competitive advantage-privileged access to customers, for instance--will have relatively few competitors to contend with, since potential competitors without an advantage, if they have their wits about them, will stay away. Thus, competitive advantages are actually barriers to entry and vice versa. In markets that are exposed, by contrast, competition is intense. If the incumbents have even brief success in earning greater than normal returns on investments, new entrants will swarm in to grab a share of the profits. Sooner or later, the additional competition will push returns as far down as the firms' costs of capital. For firms operating in such markets, the only choice is to forget about strategy and run the business as efficiently as possible. Barriers to entry are easier to maintain in a competitive arena that is "local", either in the geographic sense or in the sense of being limited to one product or a handful of related ones. The two most powerful competitive advantages-customer captivity and economies of scale-are more achievable and sustainable in circumscribed markets of this kind. Their opposites are the open markets and host of rivals that are features of globalization. Compapies entering such markets risk frittering away the advantages they secured on smaller playing fields.., Ifa company wants to grow but still obtain superior returns, the authors argue, the best strategy is to dominate a series of discrete but preferably contiguous markets and then expand only at their edges. WalMart's diminishing margins over the past 15 years are strong evidence of the danger of proceeding otherwise.

  20. A Local Galilean Invariant Thermostat.

    PubMed

    Groot, Robert D

    2006-05-01

    The thermostat introduced recently by Stoyanov and Groot (J. Chem. Phys. 2005, 122, 114112) is analyzed for inhomogeneous systems. This thermostat has one global feature, because the mean temperature used to drive the system toward equilibrium is a global average. The consequence is that the thermostat locally conserves energy rather than temperature. Thus, local temperature variations can be long-lived, although they do average out by thermal diffusion. To obtain a faster local temperature equilibration, a truly local thermostat must be introduced. To conserve momentum and, hence, to simulate hydrodynamic interactions, the thermostat must be Galilean invariant. Such a local Galilean invariant thermostat is studied here. It is shown that, by defining a local temperature on each particle, the ensemble is locally isothermal. The local temperature is obtained from a local square velocity average around each particle. Simulations on the ideal gas show that this local Nosé-Hoover algorithm has a similar artifact as dissipative particle dynamics:  the ideal gas pair correlation function is slightly distorted. This is attributed to the fact that the thermostat compensates fluctuations that are natural within a small cluster of particles. When the cutoff range rc for the square velocity average is increased, systematic errors decrease proportionally to rc(-)(3/2); hence, the systematic error can be made arbitrary small.

  1. Using a NIATx based local learning collaborative for performance improvement

    PubMed Central

    Roosa, Mathew; Scripa, Joseph S.; Zastowny, Thomas R.; Ford, James H.

    2012-01-01

    Local governments play an important role in improving substance abuse and mental health services. The structure of the local learning collaborative requires careful attention to old relationships and challenges local governmental leaders to help move participants from a competitive to collaborative environment. This study describes one county’s experience applying the NIATx process improvement model via a local learning collaborative. Local substance abuse and mental health agencies participated in two local learning collaboratives designed to improve client retention in substance abuse treatment and client access to mental health services. Results of changes implemented at the provider level on access and retention are outlined. The process of implementing evidence-based practices by using the Plan-Do-Study-Act rapid-cycle change is a powerful combination for change at the local level. Key lessons include: creating a clear plan and shared vision, recognizing that one size does not fit all, using data can help fuel participant engagement, a long collaborative may benefit from breaking it into smaller segments, and paying providers to offset costs of participation enhances their engagement. The experience gained in Onondaga County, New York, offers insights that serve as a foundation for using the local learning collaborative in other community-based organizations. PMID:21371751

  2. Relationship characteristics of women in interracial same-sex relationships.

    PubMed

    Jeong, Jae Y; Horne, Sharon G

    2009-01-01

    The purpose of this study was to examine the relationship characteristics of women in interracial same-sex relationships with respect to their current level of stress, internalized homophobia, perceived relationship equality, relationship satisfaction, and social support. Four groups were compared according to their current type of race relationship (ethnic minority women with White partners, White partners only, both ethnic minority partners, and White women with ethnic minority partners). No significant differences were found in terms of children and income; however, ethnic minority women with ethnic minority partners reported lower education attainment than the other groups. Relationally, there were no significant differences by race relationship for social support, relationship equality, relationship satisfaction, or stress. Internalized homophobia was lowest for interracial partnerships (ethnic minority paired with White partner). These findings are discussed in relationship to minority stress.

  3. Trans-local ties, local ties and psychological well-being among rural-to-urban migrants in Shanghai.

    PubMed

    Jin, Lei; Wen, Ming; Fan, Jessie X; Wang, Guixin

    2012-07-01

    During the past three decades, an estimated 200 million rural residents have moved to urban centers in China. They are "sojourners" in the cities and maintain close ties with their home communities, which we term trans-local ties. This paper examines the relationship between migrants' social ties and their mental health, and contrasts the trans-local ties with migrants' ties in the receiving communities, which are termed local ties. We expect that for the migrants, trans-local ties foster better mental health not only through providing emotional support but also through generating favorable social comparisons; whereas local ties may furnish important social support, but may also produce negative social comparisons. We use data collected in Shanghai to test our expectations. We compare the migrants to a sample of Shanghai natives to assess patterns of relationship between social ties and mental health that are unique to the migrants. We find that for the migrants, more numerous trans-local ties are associated with better mental health, whereas the number of local ties is not a significant predictor. This pattern is not observed among the Shanghai natives. Moreover, for migrants, trans-local ties foster a favorable evaluation of their status in Shanghai and buffer their perception of discrimination; in contrast, more numerous local ties tend to be associated with a more negative perception of social status. The findings highlight an often-overlooked pathway between social ties and health outcomes, namely, through influencing social comparison and perceived social status. This study also suggests that in addition to reducing institutional and personal discrimination, facilitating close bonds between the migrants and their home communities may be a productive way to foster their well-being, in the context of contemporary urban China.

  4. Size-energy relationships in ecological communities.

    PubMed

    Sewall, Brent J; Freestone, Amy L; Hawes, Joseph E; Andriamanarina, Ernest

    2013-01-01

    underlying local size-energy relationships and has important implications for predicting species interactions and for understanding the structure and dynamics of ecological communities.

  5. Relationship Maintenance on Facebook: Development of a Measure, Relationship to General Maintenance, and Relationship Satisfaction

    ERIC Educational Resources Information Center

    Dainton, Marianne

    2013-01-01

    Previous research indicates that the primary reason college students use Facebook is for relationship maintenance. The present study sought to determine the relationship between Facebook maintenance and general maintenance efforts in college student romantic relationships, as well as the impacts of such behaviors on the relationship. Survey data…

  6. Performing a local barrier operation

    DOEpatents

    Archer, Charles J; Blocksome, Michael A; Ratterman, Joseph D; Smith, Brian E

    2014-03-04

    Performing a local barrier operation with parallel tasks executing on a compute node including, for each task: retrieving a present value of a counter; calculating, in dependence upon the present value of the counter and a total number of tasks performing the local barrier operation, a base value, the base value representing the counter's value prior to any task joining the local barrier; calculating, in dependence upon the base value and the total number of tasks performing the local barrier operation, a target value of the counter, the target value representing the counter's value when all tasks have joined the local barrier; joining the local barrier, including atomically incrementing the value of the counter; and repetitively, until the present value of the counter is no less than the target value of the counter: retrieving the present value of the counter and determining whether the present value equals the target value.

  7. Performing a local barrier operation

    DOEpatents

    Archer, Charles J; Blocksome, Michael A; Ratterman, Joseph D; Smith, Brian E

    2014-03-04

    Performing a local barrier operation with parallel tasks executing on a compute node including, for each task: retrieving a present value of a counter; calculating, in dependence upon the present value of the counter and a total number of tasks performing the local barrier operation, a base value of the counter, the base value representing the counter's value prior to any task joining the local barrier; calculating, in dependence upon the base value and the total number of tasks performing the local barrier operation, a target value, the target value representing the counter's value when all tasks have joined the local barrier; joining the local barrier, including atomically incrementing the value of the counter; and repetitively, until the present value of the counter is no less than the target value of the counter: retrieving the present value of the counter and determining whether the present value equals the target value.

  8. Global/Local Dynamic Models

    SciTech Connect

    Pfeffer, A; Das, S; Lawless, D; Ng, B

    2006-10-10

    Many dynamic systems involve a number of entities that are largely independent of each other but interact with each other via a subset of state variables. We present global/local dynamic models (GLDMs) to capture these kinds of systems. In a GLDM, the state of an entity is decomposed into a globally influenced state that depends on other entities, and a locally influenced state that depends only on the entity itself. We present an inference algorithm for GLDMs called global/local particle filtering, that introduces the principle of reasoning globally about global dynamics and locally about local dynamics. We have applied GLDMs to an asymmetric urban warfare environment, in which enemy units form teams to attack important targets, and the task is to detect such teams as they form. Experimental results for this application show that global/local particle filtering outperforms ordinary particle filtering and factored particle filtering.

  9. Localized structure of Euglena bioconvection

    NASA Astrophysics Data System (ADS)

    Iima, Makoto; Shoji, Erika; Awazu, Akinori; Nishimori, Hiraku; Izumi, Shunsuke; Hiroshima University Collaboration

    2013-11-01

    Bioconvection of a suspension of Euglena gracilis, a photosensitive flagellate whose body length is approximately 50 micrometers, was experimentally studied. Under strong light intensity, Euglena has a negative phototaxis; they tend to go away from the light source. When the bright illumination is given from the bottom, a large scale spatio-temporal pattern is generated as a result of interaction between Euglena and surrounding flow. Recently, localized convection pattern had been reported, however, the generation process and interaction of the localized convection cells has not been analyzed. We performed experimental study to understand the localization mechanism, in particular, the onset of bioconvection and lateral localization behavior due to phototaxis. Experiments started from different initial condition suggests a bistability near the onset of the convection as binary fluid convection that also shows localized convection cells. Dynamics of localized convections cells, which is similar to the binary fluid convection case although the basic equations are not the same, is also reported.

  10. Rural Schoolteachers and the Pressures of Community Life: Local and Cosmopolitan Coping Strategies in Mid-Twentieth-Century Finland

    ERIC Educational Resources Information Center

    Anttila, Erkko; Vaananen, Ari

    2013-01-01

    This article discusses rural schoolteachers' relationships with local village communities in mid-twentieth-century Finland. At the time, Finnish rural teachers were typically very public figures in their local community. To deal with the pressures of their position, teachers resorted to coping strategies which the authors name "local"…

  11. LOCAL TADPOLE GALAXIES: DYNAMICS AND METALLICITY

    SciTech Connect

    Sanchez Almeida, J.; Munoz-Tunon, C.; Mendez-Abreu, J.; Elmegreen, D. M.; Elmegreen, B. G. E-mail: cmt@iac.es E-mail: elmegreen@vassar.edu

    2013-04-10

    Tadpole galaxies, with a bright peripheral clump on a faint tail, are morphological types unusual in the nearby universe but very common early on. Low mass local tadpoles were identified and studied photometrically in a previous work, which we complete here analyzing their chemical and dynamical properties. We measure H{alpha} velocity curves of seven local tadpoles, representing 50% of the initial sample. Five of them show evidence for rotation ({approx}70%), and a sixth target hints at it. Often the center of rotation is spatially offset with respect to the tadpole head (three out of five cases). The size and velocity dispersion of the heads are typical of giant H II regions, and three of them yield dynamical masses in fair agreement with their stellar masses as inferred from photometry. In four cases the velocity dispersion at the head is reduced with respect to its immediate surroundings. The oxygen metallicity estimated from [N II] {lambda}6583/H{alpha} often shows significant spatial variations across the galaxies ({approx}0.5 dex), being smallest at the head and larger elsewhere. The resulting chemical abundance gradients are opposite to the ones observed in local spirals, but agrees with disk galaxies at high redshift. We interpret the metallicity variation as a sign of external gas accretion (cold-flows) onto the head of the tadpole. The galaxies are low-metallicity outliers of the mass-metallicity relationship. In particular, two of the tadpole heads are extremely metal poor, with a metallicity smaller than a tenth of the solar value. These two targets are also very young (ages smaller than 5 Myr). All these results combined are consistent with the local tadpole galaxies being disks in early stages of assembling, with their star formation sustained by accretion of external metal-poor gas.

  12. Auditory Spatial Perception: Auditory Localization

    DTIC Science & Technology

    2012-05-01

    Teas , D. C.; Jeffress, L. A. Localization of High Frequency Tones. Journal of the Acoustical Society of America 1957, 29, 988–991. Feinstein, S...Neurophysiology 2001, 86, 2647–2666. Itoh, M.; Adel, B. von; Kelly, J. B. Sound Localization after Transection of the Commissure of Probst in the Albino Rat...Neurology 1957, 7, 655–663. Sandel, T. T.; Teas , D. C.; Feddersen, W. E.; Jeffress, L. A. Localization of Sound From Single and Paired Sources. Journal

  13. Localization oscillation in antidot lattices

    NASA Astrophysics Data System (ADS)

    Uryu, S.; Ando, T.

    1998-06-01

    The Anderson localization in square and hexagonal antidot lattices is numerically studied with the use of a Thouless number method. It is revealed that localization is very sensitive to the aspect ratio between the antidot diameter and the lattice constant. In a hexagonal lattice, both the Thouless number and the localization length oscillate with the period equal to the Al’tshuler-Aronov-Spivak oscillation. The oscillation is quite weak in a square lattice.

  14. Precipitation Aggregation and the Local Environment

    NASA Astrophysics Data System (ADS)

    Smalley, Mark

    The details of large-scale spatial structures of precipitation have only recently become apparent with the advent of high-resolution near-global observations from space-borne radars. As such, the relationships between these structures and the local environment and global climate are just beginning to emerge in the scientific community. Precipitation aggregates on a wide variety of scales, from individual boundary layer instabilities to extra-tropical cyclones. Separate aggregation states have been associated with widely varying precipitation rates and atmospheric states, motivating the inclusion of spatial information in hydrologic and climate models. This work adds to the body of knowledge surrounding large-scale precipitation aggregation and its driving factors by describing and demonstrating a new method of defining the spatial characteristics of precipitation events. The analysis relies on the high sensitivity and high resolution of the CloudSat Cloud Profiling Radar for the identification of precipitation with near-global coverage. The method is based on the dependence of the probability of precipitation on search area, or spatial resolution. Variations in this relationship are caused by variations in the principal characteristics of event spatial patterns: the relative spacing between events, the number density of events, and the overall fraction of precipitating scenes at high resolution. Here, this relationship is modeled by a stretched exponential containing two coefficients, that are shown to depict seasonal general circulation patterns as well as local weather. NASA's Modern-Era Retrospective analysis for Research and Applications is then used to place those spatial characteristics in the context of the local and large-scale environment. At regional scale, precipitation event density during the Amazon wet season is shown to be dependent on zonal wind speed. On a global scale, the relative spacing of shallow oceanic precipitation depends on the

  15. What does global mean temperature tell us about local climate?

    PubMed

    Sutton, Rowan; Suckling, Emma; Hawkins, Ed

    2015-11-13

    The subject of climate feedbacks focuses attention on global mean surface air temperature (GMST) as the key metric of climate change. But what does knowledge of past and future GMST tell us about the climate of specific regions? In the context of the ongoing UNFCCC process, this is an important question for policy-makers as well as for scientists. The answer depends on many factors, including the mechanisms causing changes, the timescale of the changes, and the variables and regions of interest. This paper provides a review and analysis of the relationship between changes in GMST and changes in local climate, first in observational records and then in a range of climate model simulations, which are used to interpret the observations. The focus is on decadal timescales, which are of particular interest in relation to recent and near-future anthropogenic climate change. It is shown that GMST primarily provides information about forced responses, but that understanding and quantifying internal variability is essential to projecting climate and climate impacts on regional-to-local scales. The relationship between local forced responses and GMST is often linear but may be nonlinear, and can be greatly complicated by competition between different forcing factors. Climate projections are limited not only by uncertainties in the signal of climate change but also by uncertainties in the characteristics of real-world internal variability. Finally, it is shown that the relationship between GMST and local climate provides a simple approach to climate change detection, and a useful guide to attribution studies.

  16. A novel local pattern descriptor--local vector pattern in high-order derivative space for face recognition.

    PubMed

    Fan, Kuo-Chin; Hung, Tsung-Yung

    2014-07-01

    In this paper, a novel local pattern descriptor generated by the proposed local vector pattern (LVP) in high-order derivative space is presented for use in face recognition. Based on the vector of each pixel constructed by computing the values between the referenced pixel and the adjacent pixels with diverse distances from different directions, the vector representation of the referenced pixel is generated to provide the 1D structure of micropatterns. With the devise of pairwise direction of vector for each pixel, the LVP reduces the feature length via comparative space transform to encode various spatial surrounding relationships between the referenced pixel and its neighborhood pixels. Besides, the concatenation of LVPs is compacted to produce more distinctive features. To effectively extract more detailed discriminative information in a given subregion, the vector of LVP is refined by varying local derivative directions from the n th-order LVP in (n-1) th-order derivative space, which is a much more resilient structure of micropatterns than standard local pattern descriptors. The proposed LVP is compared with the existing local pattern descriptors including local binary pattern (LBP), local derivative pattern (LDP), and local tetra pattern (LTrP) to evaluate the performances from input grayscale face images. In addition, extensive experiments conducting on benchmark face image databases, FERET, CAS-PEAL, CMU-PIE, Extended Yale B, and LFW, demonstrate that the proposed LVP in high-order derivative space indeed performs much better than LBP, LDP, and LTrP in face recognition.

  17. Local community playgroup participation and associations with social capital.

    PubMed

    Strange, Cecily; Bremner, Alexander; Fisher, Colleen; Howat, Peter; Wood, Lisa

    2016-08-01

    Issue addressed: The study aim was to investigate the relationships between social capital measures and playgroup participation in a local residential area for parents with children of playgroup age (1-4 years) compared with non-participation and participation in a playgroup outside the local residential area. Research indicates playgroup participation has benefits for families, however, less is known about the potential local community social capital for parents who participate in playgroups.Methods: Data were collected through a cross-sectional survey from March 2013 to January 2014 in Perth, Western Australia. The data from a group of parents (n=405) who had at least one child aged between 1 and 4 years were analysed using multivariable regression. Reported playgroup participation (local, outside the area or non-participation) in the previous 12 months was investigated for associations with three measures (Neighbourhood Cohesion Index, Social Capital and Citizenship Survey and local reciprocity) that capture attributes of social capital.Results: Participation in playgroup locally was generally associated with higher levels of social capital than both participation in playgroup outside the local area and non-participation. Mothers with two or more children fared better for social capital measures than mothers with one child.Conclusions: Participation in a locally placed playgroup may provide an important opportunity for families with children of playgroup age (1-4 years) to build social capital in their local community.So what?: Playgroups in a family's local area have the potential to foster locally placed social capital through community interaction, social networks and cohesion, which are important for mental health promotion in communities.

  18. Marketing by managing relationships.

    PubMed

    MacStravic, R S

    1984-10-01

    As competition increases and funding tightens, hospitals will have to realize that marketing largely is the managing of relationships--relationships between health care consumers and the provider. Prospective payment will make a hospital's fiscal viability increasingly sensitive to volume; stable profitability will depend on a steady level of patient utilization. And to ensure stable utilization, the hospital must create a base of loyal patients. Four marketing strategies can help to build this client base: 1. Create a strong care of essential services focused on the most significant customer needs. 2. Customize relationships by tailoring specific services to specific market segments' special needs. 3. Augment the basic service by offering extras and amenities. 4. Offer price incentives for people to become loyal customers. At least four types of patient loyalty exist, and a hospital should concentrate on fostering one or more types among its patients. Service loyalty occurs when a person always goes to the same provider for the same service. Provider loyalty exists when a person seeks a diversity of related services from the same provider. Family loyalty occurs when an entire family uses a particular provider. Organizational loyalty exists when an entire organization is oriented--through a contract or preferred provider arrangement, for example--toward a specific provider.

  19. Adverse responses to local anaesthetics.

    PubMed

    Fisher, M M; Graham, R

    1984-11-01

    Progressive challenge was used to investigate twenty-seven patients with a history of an adverse response to local anaesthesia. True allergy was detected in only one patient. The method does not exclude reactions to additives and preservatives in local anaesthetics. If preservative-free local anaesthetics are used for subsequent exposure in patients with no response to progressive challenge, subsequent exposure is safe. The possibility that some of these patients may be reacting to preservatives in the solutions cannot be excluded by such testing. Where possible preservative-free local anaesthetic preparations should be used for subsequent anaesthesia.

  20. Alleged allergy to local anaesthetics.

    PubMed

    Fisher, M M; Bowey, C J

    1997-12-01

    The aim of this study was to determine the incidence of true local anaesthetic allergy in patients with an alleged history of local anaesthetic allergy and whether subsequent exposure to local anaesthetics is safe. Two hundred and eight patients with a history of allergy to local anaesthesia were referred over a twenty-year period to our Anaesthetic Allergy Clinic. In this open study, intradermal testing was performed in three patients and progressive challenge in 202 patients. Four patients had immediate allergy and four patients delayed allergic reactions. One hundred and ninety-seven patients were not allergic to local anaesthetics. In 39 patients an adverse response to additives in local anaesthetic solutions could not be excluded. In all but one patient local anaesthesia has been given uneventfully subsequently. A history of allergy to local anaesthesia is unlikely to be genuine and local anaesthetic allergy is rare. In most instances LA allergy can be excluded from the history and the safety of LA verified by progressive challenge.

  1. Indoor localization using passive RFID

    NASA Astrophysics Data System (ADS)

    Vastianos, George E.; Kyriazanos, Dimitris M.; Segou, Olga E.; Mitilineos, Stelios A.; Thomopoulos, Stelios C. A.

    2011-06-01

    Radio frequency identification (RFID) systems based on passive tags are used successfully in a wide range of object identification applications. However, the increasing needs to meet new demands on applications of localization and tracking create a new field for evolution of the RFID technology. This paper presents the design, implementation, and evaluation of a cost-effective localization system for in-building usage that is able to localize objects that carry passive RFID tags. The RFID reading is performed by a single Reader and an array of directional antennas through multiplexing. Evaluation and experimental results from three localization algorithms based on RSSI are presented.

  2. Empowering an Indigenous Rural Community: Local Teachers for Local Schools.

    ERIC Educational Resources Information Center

    Delany, John; Wenmoth, Derek

    2001-01-01

    Christchurch College of Education (New Zealand) offers a distance teacher education course to a rural Maori community experiencing a teacher shortage. Program success is attributed to local initiative in establishing the program, significant local input into program development, attention to the student profile in course design and delivery,…

  3. Agriculture and Locality Interrelationships: Perspectives of Local Officials and Farmers.

    ERIC Educational Resources Information Center

    Moxley, Robert L.; Liles, James

    The focus of this study is the impact of urban activities (such as industry) and local governments on agriculture and the impact of agriculture on localities. This report is based on a qualitative study of an agricultural county, and interviews with community and county officials and farmers. The perceptions and opinions of officials are compared…

  4. Local State and Sector Theory in Local Quantum Physics

    NASA Astrophysics Data System (ADS)

    Ojima, Izumi; Okamura, Kazuya; Saigo, Hayato

    2016-06-01

    We define a new concept of local states in the framework of algebraic quantum field theory (AQFT). Local states are a natural generalization of states and give a clear vision of localization in the context of QFT. In terms of them, we can find a condition from which follows automatically the famous DHR selection criterion in DHR-DR theory. As a result, we can understand the condition as consequences of physically natural state preparations in vacuum backgrounds. Furthermore, a theory of orthogonal decomposition of completely positive (CP) maps is developed. It unifies a theory of orthogonal decomposition of states and order structure theory of CP maps. Using it, localized version of sectors is formulated, which gives sector theory for local states with respect to general reference representations.

  5. The Impact of Immigration Enforcement by Local Police on the Civil Rights of Latinos. Issue Brief.

    ERIC Educational Resources Information Center

    National Council of La Raza, Washington, DC.

    This paper discusses the provisions of the Illegal Immigration Reform and Immigrant Responsibility Act of 1996 (IIRIRA) (sections 642 and 133) and outlines some concerns with the new Immigration and Naturalization Service (INS) Quick Response Team initiative. It also examines the current relationships among local police, the INS, and local Latino…

  6. Investigating Local Sustainable Environmental Perspectives of Kenyan Community Members and Teachers

    ERIC Educational Resources Information Center

    Quigley, Cassie F.; Dogbey, James; Che, S. Megan; Hallo, Jeffrey

    2015-01-01

    Efforts to conserve and preserve the environment in developing or marginalized locales frequently involve a one-way transfer of knowledge and materials from a source in a more developed location. This situation often degenerates into a short-term donor project which risks little to no long-term impacts on local or indigenous relationships with the…

  7. P-16: The Last Education Reform. Book Two: Emerging Local, Regional, and State Efforts

    ERIC Educational Resources Information Center

    Rochford, Joseph A.

    2007-01-01

    This is the second book in a series entitled "P-16: The Last Education Reform." It was the purpose of the authors to chronicle the growth of existing state and local P-16 councils and compacts across the United States and to look at what might constitute successful efforts and an ideal relationship between state and local efforts. The…

  8. LOCAL VS. REGIONAL EFFECTS ON FISH DIVERSITY AS MEDIATED BY STREAMFLOW DISTURBANCE REGIME

    EPA Science Inventory

    abstract

    The interplay of local and regional processes on fish diversity is poorly understood, especially related to patterns of streamflow disturbance regime. Articulation of the relationship between flow disturbance patterns and river fishes across local to regional scal...

  9. Rethinking the Local-Global Links in Grassroots Environmental Adult Education.

    ERIC Educational Resources Information Center

    Guevara, Jose Roberto

    2000-01-01

    The Center for Environmental Concerns in the Philippines links local and global concerns through progressive contextualization, a process of adjusting education to the local context. Reflection in the practice found that these attempts emphasized scale rather than holistic relationship and had a narrow conception of the global. (SK)

  10. An Analysis of State and Local Alignment of Teacher Evaluation in Maryland

    ERIC Educational Resources Information Center

    Peterson, Serene N.

    2014-01-01

    This study explored the components of Maryland's newly-implemented teacher evaluation framework and compared state requirements with evaluations to three local school systems' evaluation procedures. The study sought to investigate the relationship between three evaluation protocols in comparison to the state requirements. Three local school…

  11. Examining the Relationship between Math Scores and English Language Proficiency

    ERIC Educational Resources Information Center

    Henry, Denfield L.

    2013-01-01

    English language learners (ELLs) at a south Florida elementary school have consistently struggled with the mathematics segment of the Florida Comprehensive Assessment Test. Examining the relationship between ELLs' mathematics scores and English proficiency might provide local educators with ideas for reversing a downward trend in ELLs' mathematics…

  12. The Economic Relationships between Institutions of Higher Education and Municipalities

    ERIC Educational Resources Information Center

    Allen, Dale H.

    2012-01-01

    The relationship between municipal government and a local, private, nonprofit institution of higher education (IHE) can be characterized as a delicate balance between conflict and cooperation. In recent years as municipal expenses have significantly increased, revenue generated from tax collection and state aid has lagged, creating an increasing…

  13. Regional Transformation Processes through the Universities-Institutions-Industry Relationship

    ERIC Educational Resources Information Center

    Cassia, Lucio; Colombelli, Alessandra; Paleari, Stefano

    2008-01-01

    The purpose of this paper is, first, to highlight the role of the relationships between universities, institutions and firms in different regional development processes working towards a knowledge economy, and, second, to draw some implications for local policy makers. Adopting the regional innovation system (RIS) approach, the authors analyse …

  14. Randomness and Non-Locality

    NASA Astrophysics Data System (ADS)

    Senno, Gabriel; Bendersky, Ariel; Figueira, Santiago

    2016-07-01

    The concepts of randomness and non-locality are intimately intertwined outcomes of randomly chosen measurements over entangled systems exhibiting non-local correlations are, if we preclude instantaneous influence between distant measurement choices and outcomes, random. In this paper, we survey some recent advances in the knowledge of the interplay between these two important notions from a quantum information science perspective.

  15. Community Control of Local Radio.

    ERIC Educational Resources Information Center

    Lewis, Peter M.

    This study was designed to determine to what extent local communities control the local radio which serves them, by what formal mechanisms their control is secured, and the underlying assumptions and goals which govern the practice of the professionals who have charge of the facilities. Two British radio stations, BBC Radio Bristol and the…

  16. How Just is Local Justice?

    ERIC Educational Resources Information Center

    Schultze, William A.

    1975-01-01

    Studies of criminal law practices suggest that variations in treatment from locality to locality depend on the judicial culture of the particular city, socioeconomic status of the accused, and the attitudes and actions of the police. This journal is available from the Law in American Society Foundation, 33 North LaSalle Street, Suite 1700; Chicago…

  17. Balancing State and Local Assessments.

    ERIC Educational Resources Information Center

    Rabinowitz, Stanley

    2001-01-01

    Describes rationale and attributes of local assessment program to augment statewide testing programs. Describes several steps to develop and implement a local assessment program, including setting priorities and goals, meeting with state officials, developing budgets and funding sources, forming development teams, providing professional…

  18. Developing Local Lifelong Guidance Strategies.

    ERIC Educational Resources Information Center

    Watts, A. G.; Hawthorn, Ruth; Hoffbrand, Jill; Jackson, Heather; Spurling, Andrea

    1997-01-01

    Outlines the background, rationale, methodology, and outcomes of developing local lifelong guidance strategies in four geographic areas. Analyzes the main components of the strategies developed and addresses a number of issues relating to the process of strategy development. Explores implications for parallel work in other localities. (RJM)

  19. Student Papers in Local History.

    ERIC Educational Resources Information Center

    Johnson County Community Coll., Overland Park, KS. Johnson County Center for Local History.

    Thirteen papers on Kansas and Johnson County, Kansas history are presented. The papers were written by students in a course at the Johnson County Center for Local History or for independent study in local history. The papers are: "Conditions and Construction of Gardner Lake"; "The History of St. Joseph's Church, Shawnee,…

  20. Volunteers Help Stretch Local Budgets.

    ERIC Educational Resources Information Center

    Valente, Maureen Godsey

    1985-01-01

    Discusses use of volunteers to augment local government services such as libraries, parks, paralegal aid, elderly care, data processing. Outlines requirements of successful programs and steps toward initiating volunteer programs. Presents case studies of volunteer programs in two Maryland communities and 41 examples of how local governments can…

  1. Local temperatures and local terms in modular Hamiltonians

    NASA Astrophysics Data System (ADS)

    Arias, Raúl E.; Blanco, David D.; Casini, Horacio; Huerta, Marina

    2017-03-01

    We show there are analogs to the Unruh temperature that can be defined for any quantum field theory and region of the space. These local temperatures are defined using relative entropy with localized excitations. We show that important restrictions arise from relative entropy inequalities and causal propagation between Cauchy surfaces. These suggest a large amount of universality for local temperatures, especially the ones affecting null directions. For regions with any number of intervals in two spacetime dimensions, the local temperatures might arise from a term in the modular Hamiltonian proportional to the stress tensor. We argue this term might be universal, with a coefficient that is the same for any theory, and check analytically and numerically that this is the case for free massive scalar and Dirac fields. In dimensions d ≥3 , the local terms in the modular Hamiltonian producing these local temperatures cannot be formed exclusively from the stress tensor. For a free scalar field, we classify the structure of the local terms.

  2. Adverse reactions triggered by dental local anesthetics: a clinical survey.

    PubMed Central

    Kaufman, E.; Goharian, S.; Katz, Y.

    2000-01-01

    One hundred and seventy-nine patients completed a questionnaire focusing on adverse reactions to dental local anesthetics as manifested by 16 signs and symptoms. Twenty-six percent of the participants reported having at least 1 adverse reaction. It was found that most of the adverse reactions occurred within the first 2 hours following the injection of local anesthetics. Pallor, palpitations, diaphoresis, and dizziness were the most common adverse reactions reported in the study. The results pointed to a significant relationship between anxiety, gender, injection technique, and procedure with a higher incidence of adverse reactions. PMID:11432179

  3. Localization scheme for relativistic spinors

    NASA Astrophysics Data System (ADS)

    Ciupka, J.; Hanrath, M.; Dolg, M.

    2011-12-01

    A new method to determine localized complex-valued one-electron functions in the occupied space is presented. The approach allows the calculation of localized orbitals regardless of their structure and of the entries in the spinor coefficient matrix, i.e., one-, two-, and four-component Kramers-restricted or unrestricted one-electron functions with real or complex expansion coefficients. The method is applicable to localization schemes that maximize (or minimize) a functional of the occupied spinors and that use a localization operator for which a matrix representation is available. The approach relies on the approximate joint diagonalization (AJD) of several Hermitian (symmetric) matrices which is utilized in electronic signal processing. The use of AJD in this approach has the advantage that it allows a reformulation of the localization criterion on an iterative 2 × 2 pair rotating basis in an analytical closed form which has not yet been described in the literature for multi-component (complex-valued) spinors. For the one-component case, the approach delivers the same Foster-Boys or Pipek-Mezey localized orbitals that one obtains from standard quantum chemical software, whereas in the multi-component case complex-valued spinors satisfying the selected localization criterion are obtained. These localized spinors allow the formulation of local correlation methods in a multi-component relativistic framework, which was not yet available. As an example, several heavy and super-heavy element systems are calculated using a Kramers-restricted self-consistent field and relativistic two-component pseudopotentials in order to investigate the effect of spin-orbit coupling on localization.

  4. Systematic and general method for quantifying localization in microscopy images

    PubMed Central

    Sheng, Huanjie; Stauffer, Weston

    2016-01-01

    ABSTRACT Quantifying the localization of molecules with respect to other molecules, cell structures and intracellular regions is essential to understanding their regulation and actions. However, measuring localization from microscopy images is often difficult with existing metrics. Here, we evaluate a metric for quantifying localization termed the threshold overlap score (TOS), and show it is simple to calculate, easy to interpret, able to be used to systematically characterize localization patterns, and generally applicable. TOS is calculated by: (i) measuring the overlap of pixels that are above the intensity thresholds for two signals; (ii) determining whether the overlap is more, less, or the same as expected by chance, i.e. colocalization, anti-colocalization, or non-colocalization; and (iii) rescaling to allow comparison at different thresholds. The above is repeated at multiple threshold combinations to generate a TOS matrix to systematically characterize the relationship between localization and signal intensities. TOS matrices were used to identify and distinguish localization patterns of different proteins in various simulations, cell types and organisms with greater specificity and sensitivity than common metrics. For all the above reasons, TOS is an excellent first line metric, particularly for cells with mixed localization patterns. PMID:27979831

  5. An Open Localization and Local Communication Embodied Sensor

    PubMed Central

    Gutiérrez, Álvaro; Campo, Alexandre; Dorigo, Marco; Amor, Daniel; Magdalena, Luis; Félix, Monasterio-Huelin

    2008-01-01

    In this paper we describe a localization and local communication system which allows situated agents to communicate locally, obtaining at the same time both the range and the bearing of the emitter without the need of any centralized control or any external reference. The system relies on infrared communications with frequency modulation and is composed of two interconnected modules for data and power measurement. Thanks to the open hardware license under which it is released, the research community can easily replicate the system at a low cost and/or adapt it for applications in sensor networks and in robotics. PMID:27873944

  6. An Open Localization and Local Communication Embodied Sensor.

    PubMed

    Gutiérrez, Alvaro; Campo, Alexandre; Dorigo, Marco; Amor, Daniel; Magdalena, Luis; Monasterio-Huelin, Félix

    2008-11-25

    In this paper we describe a localization and local communication system which allows situated agents to communicate locally, obtaining at the same time both the range and the bearing of the emitter without the need of any centralized control or any external reference. The system relies on infrared communications with frequency modulation and is composed of two interconnected modules for data and power measurement. Thanks to the open hardware license under which it is released, the research community can easily replicate the system at a low cost and/or adapt it for applications in sensor networks and in robotics.

  7. Locally rare species influence grassland ecosystem multifunctionality.

    PubMed

    Soliveres, Santiago; Manning, Peter; Prati, Daniel; Gossner, Martin M; Alt, Fabian; Arndt, Hartmut; Baumgartner, Vanessa; Binkenstein, Julia; Birkhofer, Klaus; Blaser, Stefan; Blüthgen, Nico; Boch, Steffen; Böhm, Stefan; Börschig, Carmen; Buscot, Francois; Diekötter, Tim; Heinze, Johannes; Hölzel, Norbert; Jung, Kirsten; Klaus, Valentin H; Klein, Alexandra-Maria; Kleinebecker, Till; Klemmer, Sandra; Krauss, Jochen; Lange, Markus; Morris, E Kathryn; Müller, Jörg; Oelmann, Yvonne; Overmann, Jörg; Pašalić, Esther; Renner, Swen C; Rillig, Matthias C; Schaefer, H Martin; Schloter, Michael; Schmitt, Barbara; Schöning, Ingo; Schrumpf, Marion; Sikorski, Johannes; Socher, Stephanie A; Solly, Emily F; Sonnemann, Ilja; Sorkau, Elisabeth; Steckel, Juliane; Steffan-Dewenter, Ingolf; Stempfhuber, Barbara; Tschapka, Marco; Türke, Manfred; Venter, Paul; Weiner, Christiane N; Weisser, Wolfgang W; Werner, Michael; Westphal, Catrin; Wilcke, Wolfgang; Wolters, Volkmar; Wubet, Tesfaye; Wurst, Susanne; Fischer, Markus; Allan, Eric

    2016-05-19

    Species diversity promotes the delivery of multiple ecosystem functions (multifunctionality). However, the relative functional importance of rare and common species in driving the biodiversity-multifunctionality relationship remains unknown. We studied the relationship between the diversity of rare and common species (according to their local abundances and across nine different trophic groups), and multifunctionality indices derived from 14 ecosystem functions on 150 grasslands across a land-use intensity (LUI) gradient. The diversity of above- and below-ground rare species had opposite effects, with rare above-ground species being associated with high levels of multifunctionality, probably because their effects on different functions did not trade off against each other. Conversely, common species were only related to average, not high, levels of multifunctionality, and their functional effects declined with LUI. Apart from the community-level effects of diversity, we found significant positive associations between the abundance of individual species and multifunctionality in 6% of the species tested. Species-specific functional effects were best predicted by their response to LUI: species that declined in abundance with land use intensification were those associated with higher levels of multifunctionality. Our results highlight the importance of rare species for ecosystem multifunctionality and help guiding future conservation priorities.

  8. Immunological relationship among hydrogenases.

    PubMed Central

    Kovacs, K L; Seefeldt, L C; Tigyi, G; Doyle, C M; Mortenson, L E; Arp, D J

    1989-01-01

    We examined the immunological cross-reactions of 11 different hydrogenase antigens with 9 different hydrogenase antibodies. Included were antibodies and antigens of both subunits of the hydrogenases of Bradyrhizobium japonicum and Thiocapsa roseopersicina. The results showed a strong relationship among the Ni-Fe dimeric hydrogenases. The two subunits of Ni-Fe dimeric hydrogenases appeared immunologically distinct: specific interactions occurred only when antibodies to the 60- and 30-kilodalton subunits reacted with the 60- and 30-kilodalton-subunit antigens. The interspecies cross-reactions suggested that at least one conserved protein region exists among the large subunits of these enzymes, whereas the small subunits are less conserved. Antibodies to the Fe-only bidirectional hydrogenase of Clostridium pasteurianum reacted with the Desulfovibrio vulgaris bidirectional hydrogenase. Surprisingly, antibodies to the clostridial uptake hydrogenase did not react with any of the Fe-only bidirectional hydrogenases but did react with several of the Ni-Fe dimeric hydrogenases. The two hydrogenases from C. pasteurianum were found to be quite different immunologically. The possible relationship of these findings to the structure and catalytic functions of hydrogenase are discussed. Images PMID:2464579

  9. Development of Humane Interpersonal Relationships

    ERIC Educational Resources Information Center

    Kleptsova, Elena Yuryevna; Balabanov, Anton Anatolyevich

    2016-01-01

    The article reflects some theoretical aspects of humanization of interpersonal relationships in the sphere of education. The notion "humanization of interpersonal relationships" is being analyzed. The authors offer a characterization of some parameters of relationships: orientation, modality, valence, intensity, awareness,…

  10. Peer Relationships in Child Development.

    ERIC Educational Resources Information Center

    Berndt, Thomas J., Ed.; Ladd, Gary W., Ed.

    Although hypotheses about the consequences of peer relationships for children's development have served as the foundation for much of the research into children and adolescent peer relationships, direct assessment of the impact of such relationships on children's personality, social behavior, or cognition has rarely been done. This book discusses…

  11. Distribution-abundance relationship for passerines breeding in Tunisian oases: test of the sampling hypothesis.

    PubMed

    Selmi, Slaheddine; Boulinier, Thierry

    2004-05-01

    The positive relationship between local abundance and distribution of species is a widely recognized pattern in community ecology. However, it has been suggested that this relationship can simply be an artefact of sampling because locally rare species are less detectable then locally abundant ones, and hence their distribution can easily be underestimated. Here, we use count data to investigate the relationship between distribution and abundance of passerines breeding in a sample of oases from southern Tunisia, and we provide a test of the sampling artefact hypothesis. In particular, we checked for a difference in detection probability between localized and widespread species, and we tested if increasing the sampling effort affects the significance of the relationship. A significant positive relationship between the average local abundance of passerine species and the proportion of occupied oases was found. The use of a capture-recapture approach allowed us to estimate and to compare the detection probabilities of localized and widespread species subsets. We found that localized species were locally less detectable than widespread species, which is consistent with the main assumption of the sampling artefact hypothesis. However, increasing the detection probability of species by conducting more counts did not affect the significance of the relationship, which did not give support to the sampling artefact hypothesis. Our work implies that sampling contributed to the distribution-abundance relationship we found, but that it is unlikely that such a relationship could entirely be explained by an artefact of sampling. It also underlines the insight that can be gained by using probabilistic approaches of estimating species number and detection probability when attempting to disentangle sampling from ecological effects in community ecology studies.

  12. Regulation of BLM Nucleolar Localization

    PubMed Central

    Tangeman, Larissa; McIlhatton, Michael A.; Grierson, Patrick; Groden, Joanna; Acharya, Samir

    2016-01-01

    Defects in coordinated ribosomal RNA (rRNA) transcription in the nucleolus cause cellular and organismal growth deficiencies. Bloom’s syndrome, an autosomal recessive human disorder caused by mutated recQ-like helicase BLM, presents with growth defects suggestive of underlying defects in rRNA transcription. Our previous studies showed that BLM facilitates rRNA transcription and interacts with RNA polymerase I and topoisomerase I (TOP1) in the nucleolus. The mechanisms regulating localization of BLM to the nucleolus are unknown. In this study, we identify the TOP1-interaction region of BLM by co-immunoprecipitation of in vitro transcribed and translated BLM segments and show that this region includes the highly conserved nuclear localization sequence (NLS) of BLM. Biochemical and nucleolar co-localization studies using site-specific mutants show that two serines within the NLS (S1342 and S1345) are critical for nucleolar localization of BLM but do not affect the functional interaction of BLM with TOP1. Mutagenesis of both serines to aspartic acid (phospho-mimetic), but not alanine (phospho-dead), results in approximately 80% reduction in nucleolar localization of BLM while retaining the biochemical functions and nuclear localization of BLM. Our studies suggest a role for this region in regulating nucleolar localization of BLM via modification of the two serines within the NLS. PMID:27657136

  13. Local Anesthetic-Induced Neurotoxicity

    PubMed Central

    Verlinde, Mark; Hollmann, Markus W.; Stevens, Markus F.; Hermanns, Henning; Werdehausen, Robert; Lirk, Philipp

    2016-01-01

    This review summarizes current knowledge concerning incidence, risk factors, and mechanisms of perioperative nerve injury, with focus on local anesthetic-induced neurotoxicity. Perioperative nerve injury is a complex phenomenon and can be caused by a number of clinical factors. Anesthetic risk factors for perioperative nerve injury include regional block technique, patient risk factors, and local anesthetic-induced neurotoxicity. Surgery can lead to nerve damage by use of tourniquets or by direct mechanical stress on nerves, such as traction, transection, compression, contusion, ischemia, and stretching. Current literature suggests that the majority of perioperative nerve injuries are unrelated to regional anesthesia. Besides the blockade of sodium channels which is responsible for the anesthetic effect, systemic local anesthetics can have a positive influence on the inflammatory response and the hemostatic system in the perioperative period. However, next to these beneficial effects, local anesthetics exhibit time and dose-dependent toxicity to a variety of tissues, including nerves. There is equivocal experimental evidence that the toxicity varies among local anesthetics. Even though the precise order of events during local anesthetic-induced neurotoxicity is not clear, possible cellular mechanisms have been identified. These include the intrinsic caspase-pathway, PI3K-pathway, and MAPK-pathways. Further research will need to determine whether these pathways are non-specifically activated by local anesthetics, or whether there is a single common precipitating factor. PMID:26959012

  14. Environmental justice, regulation, and the local community

    SciTech Connect

    Capek, S.M. )

    1992-01-01

    This article examines the sociological significance of the concept of environmental justice' for grassroots groups responding to toxic contamination in their local communities. Taking into account nationwide mobilization patterns in such communities, the author documents a precedent-setting episode in the city of Jacksonville, Arkansas, where citizen protests and support from national environmental groups led the Environmental Protection Agency to withdraw three Technical Assistance Grants inappropriately awarded to a group with links to a polluting industry, and subsequently to rewrite the rules for participation in such grants. As the first such challenge nationally, the Jacksonville scenario is an important test case' and permits a theoretical and practical evaluation of the relationship between social groups, technology, and the governmental regulatory process. More particularly, it gives insight into the Technical Assistance Grants program, which was set up to enable citizens living close to contaminated sites to interpret and evaluate technical information relating to such sites, but which has been undercut by a weak EPA and cooperative efforts by industries. The article concludes with an exploration of the concept of community in relation to the new construction of environmental justice engaged in by grassroots groups fighting contamination locally and nationally.

  15. Reddening and Absorption Through Local Group Galaxies

    NASA Astrophysics Data System (ADS)

    Hodge, Paul

    1997-07-01

    This project involves a photometric study of galaxies seen through the bodies of several Local Group galaxies. The high resolution of WFPC2 images will be used with automated techniques to identify galaxies at various magnitude limits. For three different magnitude regimes we will use three different techniques for studying the optical effects of the dust content: 1} for the brighter galaxies the integrated colors will be determined and compared to those of similar Hubble types in the field, which follow a fairly narrow color- type relationship; 2} for a selection of galaxies that goes to somewhat fainter limits, we will be able to measure magnitudes in three colors, allowing us to determine reddening by comparison with the field galaxy color-color relations; and 3} the identified galaxies of all brightnesses will be counted, using automated techniques, and the counts will be compared to galaxy densities in the field. The goal is a map of the TOTAL extinction and reddening through the Local Group galaxies, which can be compared to maps of the HI, molecular gas and infrared radiation, so that astrophysical conclusions can be made.

  16. Saddle point localization of molecular wavefunctions

    NASA Astrophysics Data System (ADS)

    Mellau, Georg Ch.; Kyuberis, Alexandra A.; Polyansky, Oleg L.; Zobov, Nikolai; Field, Robert W.

    2016-09-01

    The quantum mechanical description of isomerization is based on bound eigenstates of the molecular potential energy surface. For the near-minimum regions there is a textbook-based relationship between the potential and eigenenergies. Here we show how the saddle point region that connects the two minima is encoded in the eigenstates of the model quartic potential and in the energy levels of the [H, C, N] potential energy surface. We model the spacing of the eigenenergies with the energy dependent classical oscillation frequency decreasing to zero at the saddle point. The eigenstates with the smallest spacing are localized at the saddle point. The analysis of the HCN ↔ HNC isomerization states shows that the eigenstates with small energy spacing relative to the effective (v1, v3, ℓ) bending potentials are highly localized in the bending coordinate at the transition state. These spectroscopically detectable states represent a chemical marker of the transition state in the eigenenergy spectrum. The method developed here provides a basis for modeling characteristic patterns in the eigenenergy spectrum of bound states.

  17. Saddle point localization of molecular wavefunctions

    PubMed Central

    Mellau, Georg Ch.; Kyuberis, Alexandra A.; Polyansky, Oleg L.; Zobov, Nikolai; Field, Robert W.

    2016-01-01

    The quantum mechanical description of isomerization is based on bound eigenstates of the molecular potential energy surface. For the near-minimum regions there is a textbook-based relationship between the potential and eigenenergies. Here we show how the saddle point region that connects the two minima is encoded in the eigenstates of the model quartic potential and in the energy levels of the [H, C, N] potential energy surface. We model the spacing of the eigenenergies with the energy dependent classical oscillation frequency decreasing to zero at the saddle point. The eigenstates with the smallest spacing are localized at the saddle point. The analysis of the HCN ↔ HNC isomerization states shows that the eigenstates with small energy spacing relative to the effective (v1, v3, ℓ) bending potentials are highly localized in the bending coordinate at the transition state. These spectroscopically detectable states represent a chemical marker of the transition state in the eigenenergy spectrum. The method developed here provides a basis for modeling characteristic patterns in the eigenenergy spectrum of bound states. PMID:27629262

  18. Saddle point localization of molecular wavefunctions.

    PubMed

    Mellau, Georg Ch; Kyuberis, Alexandra A; Polyansky, Oleg L; Zobov, Nikolai; Field, Robert W

    2016-09-15

    The quantum mechanical description of isomerization is based on bound eigenstates of the molecular potential energy surface. For the near-minimum regions there is a textbook-based relationship between the potential and eigenenergies. Here we show how the saddle point region that connects the two minima is encoded in the eigenstates of the model quartic potential and in the energy levels of the [H, C, N] potential energy surface. We model the spacing of the eigenenergies with the energy dependent classical oscillation frequency decreasing to zero at the saddle point. The eigenstates with the smallest spacing are localized at the saddle point. The analysis of the HCN ↔ HNC isomerization states shows that the eigenstates with small energy spacing relative to the effective (v1, v3, ℓ) bending potentials are highly localized in the bending coordinate at the transition state. These spectroscopically detectable states represent a chemical marker of the transition state in the eigenenergy spectrum. The method developed here provides a basis for modeling characteristic patterns in the eigenenergy spectrum of bound states.

  19. Vibrational Spectroscopy and Quantum Localization

    NASA Astrophysics Data System (ADS)

    Fillaux, François

    These lecture-notes are meant to provide newcomers with an overview of the impact of vibrational spectroscopy in the field of nonlinear dynamics of atoms and molecules, in the perspective of energy localization. In the introduction, the terminology of nonlinear excitations and tentative experimental evidences are briefly recalled in a brief historical perspective. The basic principles of vibrational spectroscopy are presented in section 11 for infrared, Raman and inelastic neutron scattering. The potentialities for each technique to probing energy localization are discussed. In section 12, nonlinear dynamics in isolated molecules are treated within the framework of normal versus local mode representations. It is shown that these complementary representations are not necessarily distinctive of weak versus strong anharmonicity, in the context of chemical complexity. It is emphasized that local modes and energy localization are totally independent concepts. In section 4, examples of nonlinear dynamics in crystals are reviewed: multiphonon bound states, strong coupling between phonons and electrons probed with resonance Raman, local modes and quantum rotation in one-dimension probed with inelastic neutron scattering, strong coupling in hydrogen-bonded crystals and self-trapping probed with time-resolved vibrational-spectroscopy. The extended character of eigenstates in crystals free of impurities and disorder, the nature of the interaction of periodic lattices with plane waves, the Franck-Condon principle and the particle-wave duality in the quantum regime are key factors preventing observation of energy localization. It is shown that free spatially-localized nondissipative classical waves give rise to free pseudoparticles that behave as planar waves in the quantum regime. In conclusion, a clear demonstration that energy localization corresponds to eigenstates is eagerly expected for further evidencing these states with vibrational spectroscopy.

  20. Morbidity, mortality and local anaesthesia.

    PubMed

    Malamed, S F

    1999-01-01

    Two cases of local anaesthetic overdose and death are described. The patients, a four-year-old child and a 68-year old female, received local anaesthetic doses greatly in excess of those recommended. Their overdose reactions are described as well as subsequent management. The paper reviews the causes of local anaesthetic overdose, its signs and symptoms, and the recommended management of these reactions. Specific discussion as to the cause of death of these two patients and of the means to prevent such occurrences in the future concludes the paper.

  1. Speeding up local correlation methods

    SciTech Connect

    Kats, Daniel

    2014-12-28

    We present two techniques that can substantially speed up the local correlation methods. The first one allows one to avoid the expensive transformation of the electron-repulsion integrals from atomic orbitals to virtual space. The second one introduces an algorithm for the residual equations in the local perturbative treatment that, in contrast to the standard scheme, does not require holding the amplitudes or residuals in memory. It is shown that even an interpreter-based implementation of the proposed algorithm in the context of local MP2 method is faster and requires less memory than the highly optimized variants of conventional algorithms.

  2. Local governments LANDSAT applications program

    NASA Technical Reports Server (NTRS)

    1983-01-01

    The approach used to develop the internal capabilities of local governments to handle and evaluate LANDSAT data included remote sensing training, development of a low-cost digital image processing system, and technical assistance. Cost sharing, program management and coordination, and networking were also employed to address problems related to land use, water resources, environmental assessment, and air quality as experienced by urban planners. Local experiences gained in Atlanta, Georgia; Henrico County, Virginia; Oklahoma City; Oklahoma; and San Jose, California are described. Policy recommendations formulated for transferring remote sensing technologies to local governments are included.

  3. Advanced local area network concepts

    NASA Technical Reports Server (NTRS)

    Grant, Terry

    1985-01-01

    Development of a good model of the data traffic requirements for Local Area Networks (LANs) onboard the Space Station is the driving problem in this work. A parameterized workload model is under development. An analysis contract has been started specifically to capture the distributed processing requirements for the Space Station and then to develop a top level model to simulate how various processing scenarios can handle the workload and what data communication patterns result. A summary of the Local Area Network Extendsible Simulator 2 Requirements Specification and excerpts from a grant report on the topological design of fiber optic local area networks with application to Expressnet are given.

  4. Quantum localization of classical mechanics

    NASA Astrophysics Data System (ADS)

    Batalin, Igor A.; Lavrov, Peter M.

    2016-07-01

    Quantum localization of classical mechanics within the BRST-BFV and BV (or field-antifield) quantization methods are studied. It is shown that a special choice of gauge fixing functions (or BRST-BFV charge) together with the unitary limit leads to Hamiltonian localization in the path integral of the BRST-BFV formalism. In turn, we find that a special choice of gauge fixing functions being proportional to extremals of an initial non-degenerate classical action together with a very special solution of the classical master equation result in Lagrangian localization in the partition function of the BV formalism.

  5. Drug Trafficking Organizations and Local Economic Activity in Mexico

    PubMed Central

    González, Felipe

    2015-01-01

    Little is known about the relationship between illegal firms and local economic activity. In this paper I study changes in satellite night lights across Mexican municipalities after the arrival of large drug trafficking organizations in the period 2000–2010. After accounting for state trends and differences in political regimes, results indicate no significant change in night lights after the arrival of these illegal firms. Estimated coefficients are precise, robust, and similar across different drug trafficking organizations. PMID:26348041

  6. Drug Trafficking Organizations and Local Economic Activity in Mexico.

    PubMed

    González, Felipe

    2015-01-01

    Little is known about the relationship between illegal firms and local economic activity. In this paper I study changes in satellite night lights across Mexican municipalities after the arrival of large drug trafficking organizations in the period 2000-2010. After accounting for state trends and differences in political regimes, results indicate no significant change in night lights after the arrival of these illegal firms. Estimated coefficients are precise, robust, and similar across different drug trafficking organizations.

  7. Local Group Galaxy Emission-line Survey

    NASA Astrophysics Data System (ADS)

    Blaha, Cindy; Baildon, Taylor; Mehta, Shail; Garcia, Edgar; Massey, Philip; Hodge, Paul W.

    2015-01-01

    We present the results of the Local Group Galaxy Emission-line Survey of Hα emission regions in M31, M33 and seven dwarf galaxies in (NGC6822, IC10, WLM, Sextans A and B, Phoenix and Pegasus). Using data from the Local Group Galaxy Survey (LGGS - see Massey et al, 2006), we used continuum-subtracted Ha emission line images to define emission regions with a faint flux limit of 10 -17 ergs-sec-1-cm-2above the background. We have obtained photometric measurements for roughly 7450 Hα emission regions in M31, M33 and five of the seven dwarf galaxies (no regions for Phoenix or Pegasus). Using these regions, with boundaries defined by Hα-emission flux limits, we also measured fluxes for the continuum-subtracted [OIII] and [SII] images and constructed a catalog of Hα fluxes, region sizes and [OIII]/ Hα and [SII]/ Hα line ratios. The HII region luminosity functions and size distributions for the spiral galaxies M31 and M33 are compared with those of the dwarf galaxies NGC 6822 and IC10. For M31 and M33, the average [SII]/ Hα and [OIII]/ Hα line ratios, plotted as a function of galactocentric radius, display a linear trend with shallow slopes consistent with other studies of metallicity gradients in these galaxies. The galaxy-wide averages of [SII]/ Hα line ratios correlate with the masses of the dwarf galaxies following the previously established dwarf galaxy mass-metallicity relationship. The slope of the luminosity functions for the dwarf galaxies varies with galaxy mass. The Carleton Catalog of this Local Group Emission-line Survey will be made available on-line.

  8. Quantum transport localization through graphene.

    PubMed

    Srivastava, Saurabh; Kino, Hiori; Nakaharai, Shu; Verveniotis, Elisseos; Okawa, Yuji; Ogawa, Shinichi; Joachim, Christian; Aono, Masakazu

    2017-01-20

    Localization of atomic defect-induced electronic transport through a single graphene layer is calculated using a full-valence electronic structure description as a function of the defect density and taking into account the atomic-scale deformations of the layer. The elementary electronic destructive interferences leading to Anderson localization are analyzed. The low-voltage current intensity decreases with increasing length and defect density, with a calculated localization length ζ = 3.5 nm for a defect density of 5%. The difference from the experimental defect density of 0.5% required for an oxide surface-supported graphene to obtain the same ζ is discussed, pointing out how interactions of the graphene supporting surface and surface chemical modifications also control electronic transport localization.

  9. Local Authority and Town Planning.

    ERIC Educational Resources Information Center

    Duder, Bruce

    1987-01-01

    Provides an overview and definition of local authority and town planning in New Zealand. Demonstrates the relevance of planning matters to the teaching of geography. Reviews objectives of geography and specific planning methods used in several districts. (BR)

  10. Going Local to Find Help

    MedlinePlus

    ... Issues Cover Story: Traumatic Brain Injury Going Local to Find Help Past Issues / Fall 2008 Table of Contents ... description, phone numbers, maps and directions, such as To Find Out More: Visit www.ninds.nih.gov/disorders/ ...

  11. Recovering entanglement by local operations

    SciTech Connect

    D’Arrigo, A.; Lo Franco, R.; Benenti, G.; Paladino, E.; Falci, G.

    2014-11-15

    We investigate the phenomenon of bipartite entanglement revivals under purely local operations in systems subject to local and independent classical noise sources. We explain this apparent paradox in the physical ensemble description of the system state by introducing the concept of “hidden” entanglement, which indicates the amount of entanglement that cannot be exploited due to the lack of classical information on the system. For this reason this part of entanglement can be recovered without the action of non-local operations or back-transfer process. For two noninteracting qubits under a low-frequency stochastic noise, we show that entanglement can be recovered by local pulses only. We also discuss how hidden entanglement may provide new insights about entanglement revivals in non-Markovian dynamics.

  12. Local Area Networks (The Printout).

    ERIC Educational Resources Information Center

    Aron, Helen; Balajthy, Ernest

    1989-01-01

    Describes the Local Area Network (LAN), a project in which students used LAN-based word processing and electronic mail software as the center of a writing process approach. Discusses the advantages and disadvantages of networking. (MM)

  13. Composition of Local Galactic Medium

    NASA Video Gallery

    Animated view showing the neon to oxygen ratio in the neutral gas of the local cloud, as obtained with IBEX, in comparison with the ratio for the Sun and the Milky Way galaxy. There is much less ox...

  14. Nucleolar localization of myc transcripts.

    PubMed Central

    Bond, V C; Wold, B

    1993-01-01

    In situ hybridization has revealed a striking subnuclear distribution of c-myc RNA transcripts. A major fraction of the sense-strand nuclear c-myc transcripts was localized to the nucleoli. myc intron 1-containing RNAs were noticeably absent from nucleoli, accumulating instead in the nucleoplasm. The localization of myc RNA to nucleoli was shown to be common to a number of diverse cell types, including primary Sertoli cells and several cell lines. Furthermore, nucleolar localization was not restricted to c-myc and N-myc and myoD transcripts also displayed this phenomenon. In contrast, gamma-actin or lactate dehydrogenase transcripts did not display nucleolar localization. These observations suggest a new role for the nucleolus in transport and/or turnover of potential mRNAs. Images PMID:7684491

  15. Quantum transport localization through graphene

    NASA Astrophysics Data System (ADS)

    Srivastava, Saurabh; Kino, Hiori; Nakaharai, Shu; Verveniotis, Elisseos; Okawa, Yuji; Ogawa, Shinichi; Joachim, Christian; Aono, Masakazu

    2017-01-01

    Localization of atomic defect-induced electronic transport through a single graphene layer is calculated using a full-valence electronic structure description as a function of the defect density and taking into account the atomic-scale deformations of the layer. The elementary electronic destructive interferences leading to Anderson localization are analyzed. The low-voltage current intensity decreases with increasing length and defect density, with a calculated localization length ζ = 3.5 nm for a defect density of 5%. The difference from the experimental defect density of 0.5% required for an oxide surface-supported graphene to obtain the same ζ is discussed, pointing out how interactions of the graphene supporting surface and surface chemical modifications also control electronic transport localization.

  16. Fermion localization on thick branes

    SciTech Connect

    Melfo, Alejandra; Pantoja, Nelson; Tempo, Jose David

    2006-02-15

    We consider chiral fermion confinement in scalar thick branes, which are known to localize gravity, coupled through a Yukawa term. The conditions for the confinement and their behavior in the thin-wall limit are found for various different BPS branes, including double walls and branes interpolating between different AdS{sub 5} spacetimes. We show that only one massless chiral mode is localized in all these walls, whenever the wall thickness is keep finite. We also show that, independently of wall's thickness, chiral fermionic modes cannot be localized in dS{sub 4} walls embedded in a M{sub 5} spacetime. Finally, massive fermions in double wall spacetimes are also investigated. We find that, besides the massless chiral mode localization, these double walls support quasilocalized massive modes of both chiralities.

  17. A relationship between gonadotropins and visuospatial function.

    PubMed

    Gordon, H W; Lee, P A

    1986-01-01

    Follicle Stimulating Hormone (FSH) levels were negatively correlated with visuospatial function in two successive testing sessions in 32 young adult men. Men with high concentrations of FSH performed poorly on three-dimensional tests and tests of point localization. Men with low concentrations tended to perform better. Luteinizing Hormone (LH) tended to correlate positively with verbal/sequential skills and with two of the visuospatial skills for one session; testosterone was positively correlated with one spatial test. Multiple regression between the average performance on visuospatial tests and the three hormones produced Rs of 0.67 and 0.60, accounting for 39% and 29% of the variance, respectively, in Sessions 1 and 2. In women, the hormonal/behavior relationships were less clear although in many ways similar. For example, FSH was negatively correlated with one visuospatial test but only after the effects of estradiol and progesterone were partialled out. FSH was positively correlated with word fluency as was LH. With respect to sex differences women were poorer than men on the visuospatial tests and better on verbal fluency which is consistent with women's generally higher FSH levels and the negative relationship between FSH and visuospatial skills and the positive relationship with fluency.

  18. Locally homogeneous pp-waves

    NASA Astrophysics Data System (ADS)

    Globke, Wolfgang; Leistner, Thomas

    2016-10-01

    We show that every n-dimensional locally homogeneous pp-wave is a plane wave, provided it is indecomposable and its curvature operator, when acting on 2-forms, has rank greater than one. As a consequence we obtain that indecomposable, Ricci-flat locally homogeneous pp-waves are plane waves. This generalises a classical result by Jordan, Ehlers and Kundt in dimension 4. Several examples show that our assumptions on indecomposability and the rank of the curvature are essential.

  19. Local-Area-Network Simulator

    NASA Technical Reports Server (NTRS)

    Gibson, Jim; Jordan, Joe; Grant, Terry

    1990-01-01

    Local Area Network Extensible Simulator (LANES) computer program provides method for simulating performance of high-speed local-area-network (LAN) technology. Developed as design and analysis software tool for networking computers on board proposed Space Station. Load, network, link, and physical layers of layered network architecture all modeled. Mathematically models according to different lower-layer protocols: Fiber Distributed Data Interface (FDDI) and Star*Bus. Written in FORTRAN 77.

  20. Local realism of macroscopic correlations.

    PubMed

    Ramanathan, R; Paterek, T; Kay, A; Kurzyński, P; Kaszlikowski, D

    2011-08-05

    We identify conditions under which correlations resulting from quantum measurements performed on macroscopic systems (systems composed of a number of particles of the order of the Avogadro number) can be described by local realism. We argue that the emergence of local realism at the macroscopic level is caused by an interplay between the monogamous nature of quantum correlations and the fact that macroscopic measurements do not reveal properties of individual particles.

  1. Local Realism of Macroscopic Correlations

    NASA Astrophysics Data System (ADS)

    Ramanathan, R.; Paterek, T.; Kay, A.; Kurzyński, P.; Kaszlikowski, D.

    2011-08-01

    We identify conditions under which correlations resulting from quantum measurements performed on macroscopic systems (systems composed of a number of particles of the order of the Avogadro number) can be described by local realism. We argue that the emergence of local realism at the macroscopic level is caused by an interplay between the monogamous nature of quantum correlations and the fact that macroscopic measurements do not reveal properties of individual particles.

  2. Monitoring cables for local degradation

    SciTech Connect

    Bustard, L.D.; Sliter, G.E.

    1989-01-01

    Recent experiences in operating nuclear plants in the United States have demonstrated the need for an in situ cable condition monitoring technique that can assess whether installed, low-voltage, unshielded cables have local damage that could compromise their ability to function under normal and accident service conditions. This paper summarizes current US programs that have been initiated to develop a technological basis for monitoring cables with local degradation. 7 refs.

  3. Designing and Evaluating Bamboo Harvesting Methods for Local Needs: Integrating Local Ecological Knowledge and Science

    NASA Astrophysics Data System (ADS)

    Darabant, András; Rai, Prem Bahadur; Staudhammer, Christina Lynn; Dorji, Tshewang

    2016-08-01

    Dendrocalamus hamiltonii, a large, clump-forming bamboo, has great potential to contribute towards poverty alleviation efforts across its distributional range. Harvesting methods that maximize yield while they fulfill local objectives and ensure sustainability are a research priority. Documenting local ecological knowledge on the species and identifying local users' goals for its production, we defined three harvesting treatments (selective cut, horseshoe cut, clear cut) and experimentally compared them with a no-intervention control treatment in an action research framework. We implemented harvesting over three seasons and monitored annually and two years post-treatment. Even though the total number of culms positively influenced the number of shoots regenerated, a much stronger relationship was detected between the number of culms harvested and the number of shoots regenerated, indicating compensatory growth mechanisms to guide shoot regeneration. Shoot recruitment declined over time in all treatments as well as the control; however, there was no difference among harvest treatments. Culm recruitment declined with an increase in harvesting intensity. When univariately assessing the number of harvested culms and shoots, there were no differences among treatments. However, multivariate analyses simultaneously considering both variables showed that harvested output of shoots and culms was higher with clear cut and horseshoe cut as compared to selective cut. Given the ease of implementation and issues of work safety, users preferred the horseshoe cut, but the lack of sustainability of shoot production calls for investigating longer cutting cycles.

  4. 29 CFR 1620.28 - Relationship to other equal pay laws.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Relationship to other equal pay laws. 1620.28 Section 1620... PAY ACT § 1620.28 Relationship to other equal pay laws. The provisions of various State or local laws may differ from the equal pay provisions set forth in the FLSA. No provisions of the EPA will...

  5. A Typology of School-Community Relationships: Partnering and Universal Prekindergarten Policy

    ERIC Educational Resources Information Center

    Casto, Hope G.; Sipple, John W.; McCabe, Lisa A.

    2016-01-01

    School-community relationships can serve many goals ranging from enhancing student achievement to community development. This article examines the relationship between school-community partnerships and community development in light of a state prekindergarten policy that requires partnering. To understand the local responses, we propose a typology…

  6. Place, Poverty, and Algebra: A Statewide Comparative Spatial Analysis of Variable Relationships

    ERIC Educational Resources Information Center

    Hogrebe, Mark C.; Tate, William F.

    2012-01-01

    Place matters in moderating variable relationships between algebra performance and educational variables because there are differences on the socioeconomic (SES) poverty-affluence continuum that shape local contexts. This article examines relationships between variables for school district demographic composition, teaching and financial contexts,…

  7. A local earthquake coda magnitude and its relation to duration, moment M sub O, and local Richter magnitude M sub L

    NASA Technical Reports Server (NTRS)

    Suteau, A. M.; Whitcomb, J. H.

    1977-01-01

    A relationship was found between the seismic moment, M sub O, of shallow local earthquakes and the total duration of the signal, t, in seconds, measured from the earthquakes origin time, assuming that the end of the coda is composed of backscattering surface waves due to lateral heterogenity in the shallow crust following Aki. Using the linear relationship between the logarithm of M sub O and the local Richter magnitude M sub L, a relationship between M sub L and t, was found. This relationship was used to calculate a coda magnitude M sub C which was compared to M sub L for Southern California earthquakes which occurred during the period from 1972 to 1975.

  8. Cutaneous Vasodilation during Local Heating: Role of Local Cutaneous Thermosensation

    PubMed Central

    Mack, Gary W.; Foote, Kristopher M.; Nelson, W. Bradley

    2016-01-01

    We tested the hypothesis that cutaneous vasodilation during local skin heating in humans could be manipulated based upon the ability to desensitize TRPV4 ion channels by applying the thermal stimuli in a series of pulses. Each subject was instrumented with intradermal microdialysis probes in the dorsal forearm skin and perfused with 0.9% saline at 1.5 μl/min with local skin temperature controlled with a Peltier unit (9 cm2) at 34°C. Local skin temperature was manipulated for 50 min in two classic ways: a step increase to 38°C (0.1°C/s, n = 10), and a step increase to 42°C (n = 10). To desensitize TRPV4 ion channels local skin temperature was manipulated in the following way: pulsed increase to 38°C (1 pulse per min, 30 s duration, 1.0°C/s, n = 10), and 4) pulsed increase to 42°C (1.0°C/s, n = 9). Skin blood flow (SkBF, laser Doppler) was recorded directly over the middle microdialysis probe and the dialysate from all three probes were collected during baseline (34°C) and each skin heating period. The overall cutaneous vascular conductance (CVC) response to local heating was estimated from the area under the % CVCmax-time curve. The appearance of the neuropeptide calcitonin gene related peptide (CGRP) in dialysate did not change with skin heating in any protocol. For the skin temperature challenge of 34 to 38°C, the area under the % CVCmax-time curve averaged 1196 ± 295 (SD) % CVCmax•min, which was larger than the 656 ± 282% CVCmax•min during pulsed heating (p < 0.05). For the skin temperature challenge of 34 to 42°C, the area under the % CVCmax-time curve averaged 2678 ± 458% CVCmax•min, which was larger than the 1954 ± 533% CVCmax•min during pulsed heating (p < 0.05). The area under the % CVCmax•min curve, was directly proportional to the accumulated local skin thermal stress (in °C•min) (r2 = 0.62, p < 0.05, n = 39). This association indicates a critical role of local integration of thermosensitive receptors in mediating the cutaneous

  9. From Discrete Breathers to Many Body Localization and Flatbands

    NASA Astrophysics Data System (ADS)

    Flach, Sergej

    Discrete breathers (DB) and intrinsic localized modes (ILM) are synonymic dynamical states on nonlinear lattices - periodic in time and localized in space, and widely observed in many applications. I will discuss the connections between DBs and many-body localization (MBL) and the properties of DBs on flatband networks. A dense quantized gas of strongly excited DBs can lead to a MBL phase in a variety of different lattice models. Its classical counterpart corresponds to a 'nonergodic metal' in the MBL language, or to a nonGibbsean selftrapped state in the language of nonlinear dynamics. Flatband networks are lattices with small amplitude waves exhibiting macroscopic degeneracy in their band structure due to local symmetries, destructive interference, compact localized eigenstates and horizontal flat bands. DBs can preserve the compactness of localization in the presence of nonlinearity with properly tuned internal phase relationships, making them promising tools for control of the phase coherence of waves. Also at New Zealand Institute of Advanced Study, Massey University, Auckland, New Zealand.

  10. Earthquake source localization from the analysis of coseismic landslide catalogues

    NASA Astrophysics Data System (ADS)

    Meunier, Patrick; Marc, Odin; Uchida, Taro; Gorum, Tolga; Robert, Alexandra; Hovius, Niels

    2014-05-01

    In the epicentral area of large continental earthquakes, the density of seismically induced landslides is controlled by the intensity of the ground shaking, the local gradient and lithology. Once corrected for the latter parameters, the decrease of the landslide density with distance to the seismic source in depth is adequately described by a wave attenuation law. This relationship allows to localize the earthquake source using coseismic landslide catalogues and a fault plane geometry [1]. We summarize the results of the inversions of the seismic sources of the 1999 Chichi, the 2004 Niigata, the 2008 Iwate and the 2008 Sichuan earthquakes and discuss the changes in the values of the parameters, namely the source term and the quality factor, with the local geology. [1] Meunier, P., Uchida, T., & Hovius, N. (2013). Landslide patterns reveal the sources of large earthquakes. Earth and Planetary Science Letters, 363, 27-33.

  11. Citizen participation and empowerment: the case of local environmental hazards.

    PubMed

    Rich, R C; Edelstein, M; Hallman, W K; Wandersman, A H

    1995-10-01

    Local environmental hazards place millions of citizens at risk of physical, emotional, and financial harm. While the discovery of such hazards can be fundamentally disempowering for individuals and communities, few scholars have examined the dynamics of empowerment in this context. We explore the relationships among forms of empowerment, citizen participation, and local environmental hazards, and offer a model of the processes of empowerment and disempowerment appropriate to a broad range of citizen issues. On the basis of this analysis we recommend a partnership approach to community decision making that is designed both to reduce the likelihood that local environmental hazards will develop and to minimize the disempowering impact of any threats that do occur.

  12. Monaural sound localization based on structure-induced acoustic resonance.

    PubMed

    Kim, Keonwook; Kim, Youngwoong

    2015-02-06

    A physical structure such as a cylindrical pipe controls the propagated sound spectrum in a predictable way that can be used to localize the sound source. This paper designs a monaural sound localization system based on multiple pyramidal horns around a single microphone. The acoustic resonance within the horn provides a periodicity in the spectral domain known as the fundamental frequency which is inversely proportional to the radial horn length. Once the system accurately estimates the fundamental frequency, the horn length and corresponding angle can be derived by the relationship. The modified Cepstrum algorithm is employed to evaluate the fundamental frequency. In an anechoic chamber, localization experiments over azimuthal configuration show that up to 61% of the proper signal is recognized correctly with 30% misfire. With a speculated detection threshold, the system estimates direction 52% in positive-to-positive and 34% in negative-to-positive decision rate, on average.

  13. Local environmental predictors of cholera in Bangladesh and Vietnam.

    PubMed

    Emch, Michael; Feldacker, Caryl; Yunus, Mohammad; Streatfield, Peter Kim; DinhThiem, Vu; Canh, Do Gia; Ali, Mohammad

    2008-05-01

    Environmental factors have been shown to be related to cholera and thus might prove useful for prediction. In Bangladesh and Vietnam, temporal cholera distributions are related to satellite-derived and in-situ environmental time series data in order to examine the relationships between cholera and the local environment. Ordered probit models examine associations in Bangladesh; probit models examine associations at 2 sites in Vietnam. Increases in ocean chlorophyll concentration are related to an increased magnitude of cholera in Bangladesh. Increases in sea surface temperature are most influential in Hue, Vietnam, whereas increases in river height have a significant role in Nha Trang, Vietnam. Cholera appearance and epidemic magnitude are related to the local environment. Local environmental parameters have consistent effects when cholera is regular and more prevalent in endemic settings, but in situations where cholera epidemics are rare there are differential environmental effects.

  14. Global and local Joule heating effects seen by DE 2

    NASA Technical Reports Server (NTRS)

    Heelis, R. A.; Coley, W. R.

    1988-01-01

    In the altitude region between 350 and 550 km, variations in the ion temperature principally reflect similar variations in the local frictional heating produced by a velocity difference between the ions and the neutrals. Here, the distribution of the ion temperature in this altitude region is shown, and its attributes in relation to previous work on local Joule heating rates are discussed. In addition to the ion temperature, instrumentation on the DE 2 satellite also provides a measure of the ion velocity vector representative of the total electric field. From this information, the local Joule heating rate is derived. From an estimate of the height-integrated Pedersen conductivity it is also possible to estimate the global (height-integrated) Joule heating rate. Here, the differences and relationships between these various parameters are described.

  15. Calving localization at Helheim Glacier using multiple local seismic stations

    NASA Astrophysics Data System (ADS)

    Mei, M. Jeffrey; Holland, David M.; Anandakrishnan, Sridhar; Zheng, Tiantian

    2017-02-01

    A multiple-station technique for localizing glacier calving events is applied to Helheim Glacier in southeastern Greenland. The difference in seismic-wave arrival times between each pairing of four local seismometers is used to generate a locus of possible event origins in the shape of a hyperbola. The intersection of the hyperbolas provides an estimate of the calving location. This method is used as the P and S waves are not distinguishable due to the proximity of the local seismometers to the event and the emergent nature of calving signals. We find that the seismic waves that arrive at the seismometers are dominated by surface (Rayleigh) waves. The surface-wave velocity for Helheim Glacier is estimated using a grid search with 11 calving events identified at Helheim from August 2014 to August 2015. From this, a catalogue of 11 calving locations is generated, showing that calving preferentially happens at the northern end of Helheim Glacier.

  16. Local cloning of entangled states

    SciTech Connect

    Gheorghiu, Vlad; Yu Li; Cohen, Scott M.

    2010-08-15

    We investigate the conditions under which a set S of pure bipartite quantum states on a DxD system can be locally cloned deterministically by separable operations, when at least one of the states is full Schmidt rank. We allow for the possibility of cloning using a resource state that is less than maximally entangled. Our results include that: (i) all states in S must be full Schmidt rank and equally entangled under the G-concurrence measure, and (ii) the set S can be extended to a larger clonable set generated by a finite group G of order |G|=N, the number of states in the larger set. It is then shown that any local cloning apparatus is capable of cloning a number of states that divides D exactly. We provide a complete solution for two central problems in local cloning, giving necessary and sufficient conditions for (i) when a set of maximally entangled states can be locally cloned, valid for all D; and (ii) local cloning of entangled qubit states with nonvanishing entanglement. In both of these cases, we show that a maximally entangled resource is necessary and sufficient, and the states must be related to each other by local unitary 'shift' operations. These shifts are determined by the group structure, so need not be simple cyclic permutations. Assuming this shifted form and partially entangled states, then in D=3 we show that a maximally entangled resource is again necessary and sufficient, while for higher-dimensional systems, we find that the resource state must be strictly more entangled than the states in S. All of our necessary conditions for separable operations are also necessary conditions for local operations and classical communication (LOCC), since the latter is a proper subset of the former. In fact, all our results hold for LOCC, as our sufficient conditions are demonstrated for LOCC, directly.

  17. Localization and Quantitative Co-localization of Enamelin with Amelogenin

    PubMed Central

    Gallon, Victoria; Chen, Lisha; Yang, Xiudong; Moradian-Oldak, Janet

    2013-01-01

    Enamelin and amelogenin are vital proteins in enamel formation. The cooperative function of these two proteins controls crystal nucleation and morphology in vitro. We quantitatively analyzed the co-localization between enamelin and amelogenin by confocal microscopy and using two antibodies, one raised against a sequence in the porcine 32 kDa enamelin region and the other raised against full-length recombinant mouse amelogenin. We further investigated the interaction of the porcine 32 kDa enamelin and recombinant amelogenin using immuno-gold labeling. This study reports the quantitative co-localization results for postnatal days 1, 2, 3, 4, 5, 6, 7 and 8 mandibular mouse molars. We show that amelogenin and enamelin are secreted into the extracellular matrix on the cuspal slopes of the molars at day 1 and that secretion continues to at least day 8. Quantitative co-localization analysis (QCA) was performed in several different configurations using large (45 μm height, 33 μm width) and small (7 μm diameter) regions of interest to elucidate any patterns. Co-localization patterns in day 8 samples revealed that enamelin and amelogenin co-localize near the secretory face of the ameloblasts and appear to be secreted approximately in a 1:1 ratio. The degree of co-localization decreases as the enamel matures, both along the secretory face of ameloblasts and throughout the entire thickness of the enamel. Immuno-reactivity against enamelin is concentrated along the secretory face of ameloblasts, supporting the theory that this protein together with amelogenin is intimately involved in mineral induction at the beginning of enamel formation. PMID:23563189

  18. Locally adaptive document skew detection

    NASA Astrophysics Data System (ADS)

    Sauvola, Jaakko J.; Doermann, David S.; Pietikaeinen, Matti

    1997-04-01

    This paper proposes a new approach to the detection of local orientation and skew in document images. It is based on the observation that there are many documents where a single global estimate of the page skew is not sufficient. These documents require local adaptation to deal robustly with todays complex configurations of components on the page. The approach attempts to identify regions in the image which exhibit locally consistent physical properties and consistent physical properties and consistent orientation. To do this, we rapidly compute a coarse segmentation and delineate regions which differ with respect to layout and/or physical content. Each region is classified as text, graphics, mixed text/graphics, image or background using local features and additional features are extracted to estimate orientation. The local orientation decisions are propagated where appropriate to resolve ambiguity and to produce a global estimate of the skew for the page. The implementation of our algorithms is demonstrated on a set of images which have multiple regions with different orientations.

  19. SOCIAL RELATIONSHIPS AND SLEEP QUALITY

    PubMed Central

    Kent, Robert G.; Uchino, Bert N.; Cribbet, Matthew R.; Bowen, Kimberly; Smith, Timothy W.

    2015-01-01

    Background The quality of social relationships and social support appears to be associated with physical health outcomes and sleep quality. Almost all previous research in this area focuses on positive aspects of relationships. Purpose The present study thus intended to examine the links between supportive, aversive, ambivalent, and indifferent network ties and sleep quality. Methods Relationship data, PSQI-assessed sleep quality, and depression were examined in 175 middle-aged and older adults. Results Consistent with hypotheses, supportive ties were positively related to sleep quality, while aversive ties predicted worse sleep quality; associations that were primarily seen for close relationships. Ambivalent and indifferent ties were not significant predictors of sleep quality. Importantly, depression was found to mediate the link between relationship quality and sleep quality. Conclusions These data suggest the more specific types of social relationships that may be linked to poor sleep quality, and that depression appears to underlie these associations. PMID:25976874

  20. Moist wind relationships

    NASA Technical Reports Server (NTRS)

    Raymond, William H.

    1990-01-01

    The equations describing the temporal and spatial behavior of the kinematic moisture and heat flux are described. In these nonlinear equations, the contribution by diabatic processes to the large-scale flux is composed of two parts. One part is associated with a Rayleigh damping term while the other arises from temporal and spatial changes in the pressure gradient term. It was found that the influence of diabatic processes on large-scale moisture fluxes depends greatly on the degree of balance between forcing and damping terms in the governing kinematic flux equations. The existence of a near balance requires a reduction in the large-scale horizontal geostrophic wind speed. Based on an examination of the moisture flux equations, it is argued that reductions in the large-scale horizontal wind speed observed within major cumulus cloud systems help conserve large-scale moisture fluxes. The deviation of the wind from geostrophic conditions is easily estimated for a near balanced state. This wind modification induces secondary vertical circulations that contribute to convergence, creating or supporting long-lived mesoscale flows. We believe this process to be a major supporter of the mesoscale circulations observed in severe storms and squall lines. In the tropics the wind modification has an antitriptic relationship. These diagnostic findings suggest possible modifications to the wind field in the application of a cumulus parameterization, and may be important in diabatic initialization of numerical weather prediction models.

  1. Being connected to the local community through a Festival mobile application

    SciTech Connect

    Han, Kyungsik; Wirth, Richard; Hanrahan, Benjamin; Chen, Jiawei; Lee, Sooyeon; Carroll, John M.

    2016-04-25

    In this paper we report our investigation into how using and interacting with a local festival mobile app enhanced users’ festival experiences and connected them to other local users and their community. We explored the relationship between users’ perceived basic affordances of mobile technology, perceived opportunities of the festival app, and three elements that sustain the local community — attachment, engagement, and social support networks. Based on the usage logs of 348 active users, as well as survey responses from 80 users, we present a mobile-mediated local community framework and found that engagement is a key mediator of mobile experiences and facets of community.

  2. Quantitative protein localization signatures reveal an association between spatial and functional divergences of proteins.

    PubMed

    Loo, Lit-Hsin; Laksameethanasan, Danai; Tung, Yi-Ling

    2014-03-01

    Protein subcellular localization is a major determinant of protein function. However, this important protein feature is often described in terms of discrete and qualitative categories of subcellular compartments, and therefore it has limited applications in quantitative protein function analyses. Here, we present Protein Localization Analysis and Search Tools (PLAST), an automated analysis framework for constructing and comparing quantitative signatures of protein subcellular localization patterns based on microscopy images. PLAST produces human-interpretable protein localization maps that quantitatively describe the similarities in the localization patterns of proteins and major subcellular compartments, without requiring manual assignment or supervised learning of these compartments. Using the budding yeast Saccharomyces cerevisiae as a model system, we show that PLAST is more accurate than existing, qualitative protein localization annotations in identifying known co-localized proteins. Furthermore, we demonstrate that PLAST can reveal protein localization-function relationships that are not obvious from these annotations. First, we identified proteins that have similar localization patterns and participate in closely-related biological processes, but do not necessarily form stable complexes with each other or localize at the same organelles. Second, we found an association between spatial and functional divergences of proteins during evolution. Surprisingly, as proteins with common ancestors evolve, they tend to develop more diverged subcellular localization patterns, but still occupy similar numbers of compartments. This suggests that divergence of protein localization might be more frequently due to the development of more specific localization patterns over ancestral compartments than the occupation of new compartments. PLAST enables systematic and quantitative analyses of protein localization-function relationships, and will be useful to elucidate protein

  3. Some notes on Einstein relationships

    NASA Astrophysics Data System (ADS)

    Allen, Michael P.; Masters, Andrew J.

    Transport coefficients are often expressed in the form of an Einstein relationship. In this report we point out some possibly surprising properties of the correlation functions appearing in such expressions and we discuss under what conditions the relationships are true. We further consider the Einstein relationship for the shear viscosity proposed by McQuarrie [in Statistical Mechanics (Harper and Row), 1976]. On the basis both of theoretical analysis and computer simulation, we conclude that this expression is incorrect.

  4. The Child in the Community: Some Ghanaian Children's Perceptions of Local Water and Fuel Resources and Consumption.

    ERIC Educational Resources Information Center

    Knamiller, Gary W.; Obeng-Asamoah, John

    1979-01-01

    The environmental awareness of village and rural children in Ghana differed from that of urban children. This study explores the knowledge of some Ghanaian children about water and full resources and their relationship to local development issues. (Author/RE)

  5. Afghanistan’s Local War: Building Local Defense Forces

    DTIC Science & Technology

    2010-01-01

    Defense Forces . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 CHAPTER SIX Mitigating Risks ...exploited. There are, of course, risks with any strategy, as this assessment documents. But the potential risks are outweighed by the potential...gains, especially since Afghan and NATO forces can monitor and provide oversight to local defense forces and mitigate these risks . xiii Acknowledgments

  6. Locally-Referenced Ultrasonic – LPS for Localization and Navigation

    PubMed Central

    Gualda, David; Ureña, Jesús; García, Juan C.; Lindo, Alejandro

    2014-01-01

    This paper presents a flexible deployment of ultrasonic position sensors and a novel positioning algorithm suitable for the navigation of mobile robots (MRs) in extensive indoor environments. Our proposal uses several independently-referenced local positioning systems (LPS), which means that each one of them operates within its own local reference system. In a typical layout, an indoor extensive area can be covered using just a reduced set of globally-referenced LPS (GRLPS), whose beacon positions are known to the global reference system, while the rest of the space can be covered using locally-referenced LPSs (LRLPS) that can be distributed arbitrarily. The number of LRLPS and their position can be also changed at any moment. The algorithm is composed of several Bayesian filters running in parallel, so that when an MR is under the GRLPS coverage area, its position is updated by a global filter, whereas when the MR is inside the LRLPS area, its position is updated using position increments within a local filter. The navigation algorithm has been tested by simulation and with actual data obtained using a real set of ultrasonic LPSs. PMID:25412215

  7. Localization via Automorphisms of the CARs: Local Gauge Invariance

    NASA Astrophysics Data System (ADS)

    Grundling, Hendrik; Neeb, Karl-Hermann

    2010-08-01

    The classical matter fields are sections of a vector bundle E with base manifold M, and the space L 2( E) of square integrable matter fields w.r.t. a locally Lebesgue measure on M, has an important module action of {C_b^infty(M)} on it. This module action defines restriction maps and encodes the local structure of the classical fields. For the quantum context, we show that this module action defines an automorphism group on the algebra of the canonical anticommutation relations, CAR( L 2( E)), with which we can perform the analogous localization. That is, the net structure of the CAR( L 2( E)) w.r.t. appropriate subsets of M can be obtained simply from the invariance algebras of appropriate subgroups. We also identify the quantum analogues of restriction maps, and as a corollary, we prove a well-known “folk theorem,” that the CAR( L 2( E)) contains only trivial gauge invariant observables w.r.t. a local gauge group acting on E.

  8. Sound Localization in the Alligator

    PubMed Central

    Carr, Catherine E.

    2016-01-01

    In early tetrapods, it is assumed that the tympana were acoustically coupled through the pharynx and therefore inherently directional, acting as pressure difference receivers. The later closure of the middle ear cavity in turtles, archosaurs, and mammals is a derived condition, and would have changed the ear by decoupling the tympana. Isolation of the middle ears would then have led to selection for structural and neural strategies to compute sound source localization in both archosaurs and mammalian ancestors. In the archosaurs (birds and crocodilians) the presence of air spaces in the skull provided connections between the ears that have been exploited to improve directional hearing, while neural circuits mediating sound localization are well developed. In this review, we will focus primarily on directional hearing in crocodilians, where vocalization and sound localization are thought to be ecologically important, and indicate important issues still awaiting resolution. PMID:26048335

  9. Dermatomycosis Frequency and Localization Sites

    PubMed Central

    Koçinaj, Allma Ferizi; Kotori, Merita Grajqevci; Koraqi, Andi; Fida, Monika

    2015-01-01

    Introduction: Since the prevalence of skin mycotic infections is changing and is area depended we aimed to analyze the frequency of the skin myocotic infections and the appearance sites. Material and Methods: There were involved 560 patients referred to the Dermatology Clinic of University Clinical Center of Kosova during a period of one year. Results: The mean age of our study group was around thirties with a predominance of female and rural patients. Although most of cases presented with single site disease localization, we observed the increase in number of cases with more than one site localization with age. Conclusion: The increased prevalence skin mycotic infections, as well as more than one place of localization deserve a multidimensional approach. PMID:25870481

  10. Boundary Preserving Dense Local Regions.

    PubMed

    Kim, Jaechul; Grauman, Kristen

    2015-05-01

    We propose a dense local region detector to extract features suitable for image matching and object recognition tasks. Whereas traditional local interest operators rely on repeatable structures that often cross object boundaries (e.g., corners, scale-space blobs), our sampling strategy is driven by segmentation, and thus preserves object boundaries and shape. At the same time, whereas existing region-based representations are sensitive to segmentation parameters and object deformations, our novel approach to robustly sample dense sites and determine their connectivity offers better repeatability. In extensive experiments, we find that the proposed region detector provides significantly better repeatability and localization accuracy for object matching compared to an array of existing feature detectors. In addition, we show our regions lead to excellent results on two benchmark tasks that require good feature matching: weakly supervised foreground discovery and nearest neighbor-based object recognition.

  11. Localized structures in convective experiments

    NASA Astrophysics Data System (ADS)

    Burguete, J.; Mancini, H.

    2014-01-01

    In this work we review localized structures appearing in thermo-convective experiments performed in extended (large "aspect ratio") fluid layers. After a brief general review (not exhaustive), we focus on some results obtained in pure fluids in a Bénard-Marangoni system with non-homogeneous heating where some structures of this kind appear. The experimental results are compared in reference to the most classical observed in binary mixtures experiments or simulations. In the Bénard-Marangoni experiment we present the stability diagram where localized structures appear and the typical situations where these local mechanisms have been studied experimentally. Some new experimental results are also included. The authors want to honor Prof. H. Brand in his 60th. birthday and to thank him for helpful discussions.

  12. LULUs: locally unwanted land uses

    SciTech Connect

    Popper, F.J.

    1983-06-01

    A LULU is a locally unwanted land use. It may be an old-age home or a nuclear-waste-disposal site. People need it but do not want to live next to it. Some characteristics LULUs have in common are: opposition (more or less organized), costs to the neighborhood (real or perceived), support from conservatives for LULUs of the right, support from liberals for LULUs of the left, and some local support. Today's LULU may be tomorrow's prize; witness the 1982 competition for a state prison by 21 towns in depressed Illinois. Regional and national LULUs, while offering (or appearing to offer) a regional or national benefit, put financial and environmental costs and social stresses on a locality. Governmental and legal questions confront the decision-makers who must untangle these conflicts.

  13. Sound localization in the alligator.

    PubMed

    Bierman, Hilary S; Carr, Catherine E

    2015-11-01

    In early tetrapods, it is assumed that the tympana were acoustically coupled through the pharynx and therefore inherently directional, acting as pressure difference receivers. The later closure of the middle ear cavity in turtles, archosaurs, and mammals is a derived condition, and would have changed the ear by decoupling the tympana. Isolation of the middle ears would then have led to selection for structural and neural strategies to compute sound source localization in both archosaurs and mammalian ancestors. In the archosaurs (birds and crocodilians) the presence of air spaces in the skull provided connections between the ears that have been exploited to improve directional hearing, while neural circuits mediating sound localization are well developed. In this review, we will focus primarily on directional hearing in crocodilians, where vocalization and sound localization are thought to be ecologically important, and indicate important issues still awaiting resolution.

  14. Local non-equilibrium thermodynamics

    PubMed Central

    Jinwoo, Lee; Tanaka, Hajime

    2015-01-01

    Local Shannon entropy lies at the heart of modern thermodynamics, with much discussion of trajectory-dependent entropy production. When taken at both boundaries of a process in phase space, it reproduces the second law of thermodynamics over a finite time interval for small scale systems. However, given that entropy is an ensemble property, it has never been clear how one can assign such a quantity locally. Given such a fundamental omission in our knowledge, we construct a new ensemble composed of trajectories reaching an individual microstate, and show that locally defined entropy, information, and free energy are properties of the ensemble, or trajectory-independent true thermodynamic potentials. We find that the Boltzmann-Gibbs distribution and Landauer's principle can be generalized naturally as properties of the ensemble, and that trajectory-free state functions of the ensemble govern the exact mechanism of non-equilibrium relaxation. PMID:25592077

  15. Local Flaps of The Hand

    PubMed Central

    Rehim, Shady A.; Chung, Kevin C.

    2014-01-01

    Synopsis A local flap consists of skin and subcutaneous tissue that is harvested from a site nearby a given defect while maintaining its intrinsic blood supply. When a soft tissue defect of the hand is not amenable to primary closure or skin grafting, local skin flaps can be a used as a reliable source of soft tissue replacement that replaces like with like. Flaps are categorized based on their composition, method of transfer, flap design and blood supply, yet flap circulation is considered the most critical factor for the flap survival. This article reviews the classification of local skin flaps of the hand and offers a practical reconstructive approach for several soft tissue defects of the hand and digits. PMID:24731606

  16. Foreign English Language Teachers' Local Pedagogy

    ERIC Educational Resources Information Center

    Eusafzai, Hamid Ali Khan

    2015-01-01

    ELT methods have been criticized for being limited and inadequate. Postmethod pedagogy has been offered as an alternate to these methods. The postmethod pedagogy emphasises localization of pedagogy and celebrates local culture, teachers and knowledge. Localizing pedagogy is easy for local teachers as knowledge and understanding of the local comes…

  17. Spanning the Local Government Information Gap.

    ERIC Educational Resources Information Center

    Durrance, Joan C.

    1985-01-01

    Discussion of implications of highly decentralized nature of local government for collection of local documents highlights meaning of access, effect of local government environment on access to local government information, library responses, and tools that can assist libraries in increasing citizen and government access to local government…

  18. Local management of rectal neoplasia.

    PubMed

    Touzios, John; Ludwig, Kirk A

    2008-11-01

    The treatment of rectal neoplasia, whether benign or malignant, challenges the surgeon. The challenge in treating rectal cancer is selecting the proper approach for the appropriate patient. In a small number of rectal cancer patients local excision may be the best approach. In an attempt to achieve two goals-cure of disease with a low rate of local failure and maintenance of function and quality of life-multiple approaches can be utilized. The key to obtaining a good outcome for any one patient is balancing the competing factors that impact on these goals. Any effective treatment aimed at controlling rectal cancer in the pelvis must take into account the disease in the bowel wall itself and the disease, or potential disease, in the mesorectum. The major downside of local excision techniques is the potential of leaving untreated disease in the mesorectum. Local management techniques avoid the potential morbidity, mortality, and functional consequences of a major abdominal radical resection and are thus quite effective in achieving the maintenance of function and quality of life goal. The issue for the transanal techniques is how they fare in achieving the first goal-cure of the cancer while keeping local recurrence rates to an absolute minimum. Without removing both the rectum and the mesorectum there is no completely accurate way to determine whether a rectal cancer has moved outside the bowel wall, so any decision on local management of a rectal neoplasm is a calculated risk. For benign neoplasia, the challenge is removing the lesion without having to resort to a major abdominal procedure.

  19. Biodiversity conservation in local planning.

    PubMed

    Miller, James R; Groom, Martha; Hess, George R; Steelman, Toddi; Stokes, David L; Thompson, Jan; Bowman, Troy; Fricke, Laura; King, Brandon; Marquardt, Ryan

    2009-02-01

    Local land-use policy is increasingly being recognized as fundamental to biodiversity conservation in the United States. Many planners and conservation scientists have called for broader use of planning and regulatory tools to support the conservation of biodiversity at local scales. Yet little is known about the pervasiveness of these practices. We conducted an on-line survey of county, municipal, and tribal planning directors (n =116) in 3 geographic regions of the United States: metropolitan Seattle, Washington; metropolitan Des Moines, Iowa; and the Research Triangle, North Carolina. Our objectives were to gauge the extent to which local planning departments address biodiversity conservation and to identify factors that facilitate or hinder conservation actions in local planning. We found that biodiversity conservation was seldom a major consideration in these departments. Staff time was mainly devoted to development mandates and little time was spent on biodiversity conservation. Regulations requiring conservation actions that might benefit biodiversity were uncommon, with the exception of rules governing water quality in all 3 regions and the protection of threatened and endangered species in the Seattle region. Planning tools that could enhance habitat conservation were used infrequently. Collaboration across jurisdictions was widespread, but rarely focused on conservation. Departments with a conservation specialist on staff tended to be associated with higher levels of conservation actions. Jurisdictions in the Seattle region also reported higher levels of conservation action, largely driven by state and federal mandates. Increased funding was most frequently cited as a factor that would facilitate greater consideration of biodiversity in local planning. There are numerous opportunities for conservation biologists to play a role in improving conservation planning at local scales.

  20. Operator Localization of Virtual Objects

    NASA Technical Reports Server (NTRS)

    Ellis, Stephen R.; Menges, Brian M.; Null, Cynthia H. (Technical Monitor)

    1998-01-01

    Errors in the localization of nearby virtual objects presented via see-through, helmet mounted displays are examined as a function of viewing conditions and scene content. Monocular, biocular or stereoscopic presentation of the virtual objects, accommodation (required focus), subjects'age, and the position of physical surfaces are examined. Nearby physical surfaces are found to introduce localization errors that differ depending upon the other experimental factors. The apparent physical size and transparency of the virtual objects and physical surfaces respectively are also influenced by their relative position when superimposed. Design implications are discussed.