EFL Learners' Perceptions of Using LMS

ERIC Educational Resources Information Center

Srichanyachon, Napaporn

2014-01-01

The purpose of this study is to present the views, attitudes, and perspectives of undergraduate students using Learning Management System (LMS) along with traditional face-to-face learning. It attempts to understand the factors that influence the adoption of LMS based on users' own experience. The samples were 198 undergraduate students enrolled…

Tryout and Evaluation of Prototype LMS (Learning Mastery System) Training System Under Exclusive Use Agreement.

ERIC Educational Resources Information Center

McDonald, Cheryl; Hylton, John A.

In 1970-1971 Learning Mastery System (LMS) materials were made available to schools within the state of California under an Exclusive Use Agreement. The LMS is a set of materials and procedures prepared by the Southwest Regional Laboratory (SWRL) as an objectives-based framework to assist in managing the learning activities of existing reading…

Using a Learning Management System to Personalise Learning for Primary School Students

ERIC Educational Resources Information Center

Edmunds, Bronwyn; Hartnett, Maggie

2014-01-01

This paper reports on one aspect of a descriptive multiple-case study which set out to explore the role of a learning management system (LMS) in personalising learning for students from the perspective of three teachers in one primary school in New Zealand. The intention was to provide insight into the role the LMS could play in classrooms when…

LTSA Conformance Testing to Architectural Design of LMS Using Ontology

ERIC Educational Resources Information Center

Sengupta, Souvik; Dasgupta, Ranjan

2017-01-01

This paper proposes a new methodology for checking conformance of the software architectural design of Learning Management System (LMS) to Learning Technology System Architecture (LTSA). In our approach, the architectural designing of LMS follows the formal modeling style of Acme. An ontology is built to represent the LTSA rules and the software…

An Analysis of Technological Issues Emanating from Faculty Transition to a New Learning Management System

ERIC Educational Resources Information Center

Sanga, Mapopa William

2016-01-01

This case study investigated the process 119 faculty members underwent as they transitioned from using Desire to Learn (D2L) learning management system (LMS), to using Canvas LMS. Other than analyzing technological issues faculty members encountered while navigating various aspects of the Canvas interface, the study also analyzed technological…

Evaluating Learning Management System (LMS)-Facilitated Delivery of Universal Design for Learning (UDL)

ERIC Educational Resources Information Center

Bryans Bongey, Sarah

2012-01-01

This quantitative study involved 157 students in two sections of an undergraduate class in general biology, as well as one instructor who taught both sections of the course. It used resources from the Center for Applied Special Technologies (CAST) to evaluate the viability of a Learning Management System (LMS) to provide Universal Design for…

Selecting a Learning Management System (LMS) in Developing Countries: Instructors' Evaluation

ERIC Educational Resources Information Center

Cavus, Nadire

2013-01-01

Learning management systems (LMSs) contain hidden costs, unclear user environments, bulky developer and administration manuals, and limitations with regard to interoperability, integration, localization, and bandwidth requirements. Careful evaluation is required in selecting the most appropriate LMS for use, and this is a general problem in…

Developing Adaptable Online Information Literacy Modules for a Learning Management System

ERIC Educational Resources Information Center

Mune, Christina; Goldman, Crystal; Higgins, Silke; Eby, Laurel; Chan, Emily K.; Crotty, Linda

2015-01-01

Higher education institutions increasingly utilize learning management systems (LMS) to teach courses and programs in hybrid or online-only formats. Providing information literacy instruction in these emerging digital environments poses challenges to librarians as the delivery of instruction requires familiarity with navigating an LMS and…

Implementing Innovation: An Exploration of a Learning Management System Transition

ERIC Educational Resources Information Center

Strawser, Michael G.; Apostel, Shawn; O' Keefe, Moira; Simons, Crystal

2018-01-01

Learning management systems (LMS) are fixtures on higher education campuses. As LMS use continues to increase, faculty development professionals should consider how system use is encouraged and implemented on campus, especially amongst faculty. Using Ely's (1990) technology-specific conditions that facilitate the implementation of an innovation,…

Determining the Effects of LMS Learning Behaviors on Academic Achievement in a Learning Analytic Perspective

ERIC Educational Resources Information Center

Firat, Mehmet

2016-01-01

Two of the most important outcomes of learning analytics are predicting students' learning and providing effective feedback. Learning Management Systems (LMS), which are widely used to support online and face-to-face learning, provide extensive research opportunities with detailed records of background data regarding users' behaviors. The purpose…

Perceptions and Use of Learning Management System Tools and Other Technologies in Higher Education: A Preliminary Analysis

ERIC Educational Resources Information Center

Borboa, Danielle; Joseph, Mathew; Spake, Deborah; Yazdanparast, Atefeh

2017-01-01

This study examines student views and use of technology in conjunction with university coursework. Results reveal that there is widespread use of Microsoft PowerPoint and certain learning management system (LMS) features; however, there are significant differences in views concerning the degree to which these LMS tools enhance learning based on…

An Analysis of Implementation Issues for the Searchable Content Object Reference Model (SCORM) in Navy Education and Training

DTIC Science & Technology

2003-09-01

content objects to be used and reused within civilian and military education and training Learning Management Systems (LMS) across the World Wide Web...to be used and reused within civilian and military education and training Learning Management Systems (LMS) across the World Wide Web. vi...1998, SUBJECT: ENHANCING LEARNING AND EDUCATION THROUGH TECHNOLOGY

Toolkit Approach to Integrating Library Resources into the Learning Management System

ERIC Educational Resources Information Center

Black, Elizabeth L.

2008-01-01

As use of learning management systems (LMS) increases, it is essential that librarians are there. Ohio State University Libraries took a toolkit approach to integrate library content in the LMS to facilitate creative and flexible interactions between librarians, students and faculty in Ohio State University's large and decentralized academic…

Factors Predicting Online University Students' Use of a Mobile Learning Management System (m-LMS)

ERIC Educational Resources Information Center

Joo, Young Ju; Kim, Nari; Kim, Nam Hee

2016-01-01

This study analyzed the relationships among factors predicting online university students' actual usage of a mobile learning management system (m-LMS) through a structural model. Data from 222 students in a Korean online university were collected to investigate integrated relationships among their perceived ease of use, perceived usefulness,…

Student use of a Learning Management System for group projects: A case study investigating interaction, collaboration, and knowledge construction

NASA Astrophysics Data System (ADS)

Lonn, Steven D.

Web-based Learning Management Systems (LMS) allow instructors and students to share instructional materials, make class announcements, submit and return course assignments, and communicate with each other online. Previous LMS-related research has focused on how these systems deliver and manage instructional content with little concern for how students' constructivist learning can be encouraged and facilitated. This study investigated how students use LMS to interact, collaborate, and construct knowledge within the context of a group project but without mediation by the instructor. The setting for this case study was students' use in one upper-level biology course of the local LMS within the context of a course-related group project, a mock National Institutes of Health grant proposal. Twenty-one groups (82 students) voluntarily elected to use the LMS, representing two-thirds of all students in the course. Students' peer-to-peer messages within the LMS, event logs, online surveys, focus group interviews, and instructor interviews were used in order to answer the study's overarching research question. The results indicate that students successfully used the LMS to interact and, to a significant extent, collaborate, but there was very little evidence of knowledge construction using the LMS technology. It is possible that the ease and availability of face-to-face meetings as well as problems and limitations with the technology were factors that influenced whether students' online basic interaction could be further distinguished as collaboration or knowledge construction. Despite these limitations, students found several tools and functions of the LMS useful for their online peer interaction and completion of their course project. Additionally, LMS designers and implementers are urged to consider previous literature on computer-supported collaborative learning environments in order to better facilitate independent group projects within these systems. Further research is needed to identify the best types of scaffolds and overall technological improvements in order to provide support for online collaboration and knowledge construction.

Examining the Effect of Academic Procrastination on Achievement Using LMS Data in E-Learning

ERIC Educational Resources Information Center

You, Ji Won

2015-01-01

This study aimed to investigate the effect of academic procrastination on e-learning course achievement. Because all of the interactions among students, instructors, and contents in an e-learning environment were automatically recorded in a learning management system (LMS), procrastination such as the delays in weekly scheduled learning and late…

The Other Side of the LMS: Considering Implementation and Use in the Adoption of an LMS in Online and Blended Learning Environments

ERIC Educational Resources Information Center

Black, Erik W.; Beck, Dennis; Dawson, Kara; Jinks, Susan; DiPietro, Meredith

2007-01-01

There are more similarities than differences among learning management system (LMS) software products. In a recent study, Carriere, Challborn, and Moore compared a variety of LMSs and went as far as to suggest that the only real differences between systems lie in marketing approaches. In addition, because LMSs have interchangeable parts, those…

Investigating IT Faculty Resistance to Learning Management System Adoption Using Latent Variables in an Acceptance Technology Model.

PubMed

Bousbahi, Fatiha; Alrazgan, Muna Saleh

2015-01-01

To enhance instruction in higher education, many universities in the Middle East have chosen to introduce learning management systems (LMS) to their institutions. However, this new educational technology is not being used at its full potential and faces resistance from faculty members. To investigate this phenomenon, we conducted an empirical research study to uncover factors influencing faculty members' acceptance of LMS. Thus, in the Fall semester of 2014, Information Technology faculty members were surveyed to better understand their perceptions of the incorporation of LMS into their courses. The results showed that personal factors such as motivation, load anxiety, and organizational support play important roles in the perception of the usefulness of LMS among IT faculty members. These findings suggest adding these constructs in order to extend the Technology acceptance model (TAM) for LMS acceptance, which can help stakeholders of the university to implement the use of this system. This may assist in planning and evaluating the use of e-learning.

Investigating IT Faculty Resistance to Learning Management System Adoption Using Latent Variables in an Acceptance Technology Model

PubMed Central

Bousbahi, Fatiha; Alrazgan, Muna Saleh

2015-01-01

To enhance instruction in higher education, many universities in the Middle East have chosen to introduce learning management systems (LMS) to their institutions. However, this new educational technology is not being used at its full potential and faces resistance from faculty members. To investigate this phenomenon, we conducted an empirical research study to uncover factors influencing faculty members' acceptance of LMS. Thus, in the Fall semester of 2014, Information Technology faculty members were surveyed to better understand their perceptions of the incorporation of LMS into their courses. The results showed that personal factors such as motivation, load anxiety, and organizational support play important roles in the perception of the usefulness of LMS among IT faculty members. These findings suggest adding these constructs in order to extend the Technology acceptance model (TAM) for LMS acceptance, which can help stakeholders of the university to implement the use of this system. This may assist in planning and evaluating the use of e-learning. PMID:26491712

A Clustering Methodology of Web Log Data for Learning Management Systems

ERIC Educational Resources Information Center

Valsamidis, Stavros; Kontogiannis, Sotirios; Kazanidis, Ioannis; Theodosiou, Theodosios; Karakos, Alexandros

2012-01-01

Learning Management Systems (LMS) collect large amounts of data. Data mining techniques can be applied to analyse their web data log files. The instructors may use this data for assessing and measuring their courses. In this respect, we have proposed a methodology for analysing LMS courses and students' activity. This methodology uses a Markov…

Researching Instructional Use and the Technology Acceptation of Learning Management Systems by Secondary School Teachers

ERIC Educational Resources Information Center

De Smet, Cindy; Bourgonjon, Jeroen; De Wever, Bram; Schellens, Tammy; Valcke, Martin

2012-01-01

The aim of this large-scale study was to understand the technology acceptation of learning management systems (LMS) by secondary school teachers and to investigate the instructional use of LMS, distinguishing between informational use and communicational use. The predictive model further includes: perceived usefulness, perceived ease of use,…

The Learning Management System at the Defence University: Awareness and Application

ERIC Educational Resources Information Center

Juhary, Jowati

2013-01-01

This brief paper examines the issues of awareness and application of a Learning Management System (LMS) used at the National Defence University of Malaysia (NDUM), Kuala Lumpur Malaysia. The paper argues that due to the discouraging responses from academics at the university on using the LMS, proactive measures must be taken immediately in order…

Academic Success Is about Self-Efficacy Rather than Frequency of Use of the Learning Management System

ERIC Educational Resources Information Center

Broadbent, Jaclyn

2016-01-01

Previous studies have investigated the association between the frequency of student learning management system (LMS) use (logins, discussion board use, resources used, etc.) and academic achievement. These studies indicate that low LMS use by students is likely to result in less academic success. However, these models fail to take into account…

Predicting the Adoption of E-Learning Management System: A Case of Selected Private Universities in Nigeria

ERIC Educational Resources Information Center

Nicholas-Omoregbe, Olanike Sharon; Azeta, Ambrose Agbon; Chiazor, Idowu Aigbovo; Omoregbe, Nicholas

2017-01-01

Despite the availability of studies on e-learning management system (eLMS) using information system models, its theoretical foundations have not yet captured social constructs that are peculiar to developing countries including Nigeria. This study was undertaken with the aim of investigating factors that could influence eLMS adoption in higher…

LMS Use and Instructor Performance: The Role of Task-Technology Fit

ERIC Educational Resources Information Center

McGill, Tanya; Klobas, Jane; Renzi, Stefano

2011-01-01

The introduction of learning management systems (LMS) has changed the way in which instructors work. This paper uses Goodhue and Thompson's (1995) technology-to-performance chain (TPC) to explore the roles of task-technology fit (TTF) and level of LMS use in the performance impacts of LMS for instructors. A mixed method approach was used: an…

A Data Mining Approach to Improve Re-Accessibility and Delivery of Learning Knowledge Objects

ERIC Educational Resources Information Center

Sabitha, Sai; Mehrotra, Deepti; Bansal, Abhay

2014-01-01

Today Learning Management Systems (LMS) have become an integral part of learning mechanism of both learning institutes and industry. A Learning Object (LO) can be one of the atomic components of LMS. A large amount of research is conducted into identifying benchmarks for creating Learning Objects. Some of the major concerns associated with LO are…

Breaking down the LMS Walls

ERIC Educational Resources Information Center

Hotrum, Michael

2005-01-01

The traditional packaging of electronic learning--the learning management system (LMS)--is progressively being regarded as a hindrance to effective online learning. Its design, functionality, complexity, price, and value are being questioned. A new generation of Web-based tools and approaches is evolving that are better suited to meet the need for…

An Examination of Faculty and Student Online Activity: Predictive Relationships of Student Academic Success in a Learning Management System (LMS)

ERIC Educational Resources Information Center

Stamm, Randy Lee

2013-01-01

The purpose of this mixed method research study was to examine relationships in student and instructor activity logs and student performance benchmarks specific to enabling early intervention by the instructor in a Learning Management System (LMS). Instructor feedback was collected through a survey instrument to demonstrate perceived importance of…

Learning Management Systems: Coupled Simulations and Assessments in a Digital Systems Course

ERIC Educational Resources Information Center

Wuttke, Heinz-Dietrich; Henke, Karsten

2009-01-01

Purpose: The content, provided in learning management systems (LMS), is often text oriented as in a usual textbook, extended by some animations and links. Hands on activities and experiments are not possible. The paper aims to give an overview about the concept to couple smart simulation and assessment tools with an LMS to provide a more…

Embedding a learning management system into an undergraduate medical informatics course in Saudi Arabia: lessons learned.

PubMed

Zakaria, Nasriah; Jamal, Amr; Bisht, Shekhar; Koppel, Cristina

2013-01-01

Public universities in Saudi Arabia today are making substantial investments in e-learning as part of their educational system, especially in the implementation of learning management systems (LMS). To our knowledge, this is the first study conducted in Saudi Arabia exploring medical students' experience with an LMS, particularly as part of a medical informatics course. This study investigates students' use of various features of the LMS embedded in a recently implemented medical informatics course. A mixed methodology approach was employed. Survey questionnaires were distributed to all third year medical informatics students at the end of the course. In addition, two focus group sessions were conducted with twelve students. A thematic analysis of the focus group was performed. A total of 265 third year medical student surveys (167/265, 63% male and 98/265, 37% female) were completed and analyzed. Overall, 50.6% (134/265) of the students agreed that the course was well planned and up-to-date, had clearly stated objectives and clear evaluation methods, appropriate course assignment, and that the LMS offered easy navigation. Most of the students rated the course as good/fair overall. In general, females were 10.4% more likely to prefer the LMS, as revealed by higher odd ratios (odds ratio [OR] 1.104, 95% CI 0.86-1.42) compared to males. Survey results showed that students' use of LMS tools increased after taking the course compared to before taking the course. The full model containing all items were statistically significant (χ(2) 25=69.52, P<.001, n=243), indicating that the model was able to distinguish between students who had positive attitudes towards LMS and those who did not. The focus group, however, revealed that the students used social networking for general use rather than learning purposes, but they were using other Internet resources and mobile devices for learning. Male students showed a higher preference for using technology in general to enhance learning activities. Overall, medical student attitudes towards the LMS were generally positive. Students also wanted a reminder and notification tool to help them stay updated with course events. Interestingly, a subset of students had been running a parallel LMS of their own that has features worth exploring and could be integrated with an official LMS in the future. To our knowledge, this was the first time that an LMS was used in a medical informatics course. Students showed interest in adapting various LMS tools to enhance their learning and gained more knowledge through familiarity with the tool. Researching an official LMS also revealed the existence of a parallel student-created LMS. This could allow teacher-led and student-led platforms to be integrated in the future for an enhanced student-centered experience.

Adaptivity in ProPer: An Adaptive SCORM Compliant LMS

ERIC Educational Resources Information Center

Kazanidis, Ioannis; Satratzemi, Maya

2009-01-01

Adaptive Educational Hypermedia Systems provide personalized educational content to learners. However most of them do not support the functionality of Learning Management Systems (LMS) and the reusability of their courses is hard work. On the other hand some LMS support SCORM specifications but do not provide adaptive features. This article…

Architectural Design of a LMS with LTSA-Conformance

ERIC Educational Resources Information Center

Sengupta, Souvik; Dasgupta, Ranjan

2017-01-01

This paper illustrates an approach for architectural design of a Learning Management System (LMS), which is verifiable against the Learning Technology System Architecture (LTSA) conformance rules. We introduce a new method for software architectural design that extends the Unified Modeling Language (UML) component diagram with the formal…

The LMS Selection Process: Practices and Considerations. ECAR Research Bulletin

ERIC Educational Resources Information Center

Cavanagh, Thomas B.

2014-01-01

With more than 80% of institutions offering online learning options and even more using web technologies to enhance traditional classroom instruction, the learning management system (LMS) is increasingly an indispensable, enterprise-level technology for today's colleges and universities. Naturally, each institution has a unique set of…

EFL Instructors' Perceptions of Usefulness and Ease of Use of the LMS Manaba

ERIC Educational Resources Information Center

Toland, Sean; White, Jeremy; Mills, Daniel; Bolliger, Doris U.

2014-01-01

Learning Management Systems (LMSs) have become important tools in higher education language instruction, which can facilitate both student learning and the administration of courses. The decision regarding which LMS a particular university adopts is a complicated process where the needs and opinions of several stakeholders, including…

Constructing Proxy Variables to Measure Adult Learners' Time Management Strategies in LMS

ERIC Educational Resources Information Center

Jo, Il-Hyun; Kim, Dongho; Yoon, Meehyun

2015-01-01

This study describes the process of constructing proxy variables from recorded log data within a Learning Management System (LMS), which represents adult learners' time management strategies in an online course. Based on previous research, three variables of total login time, login frequency, and regularity of login interval were selected as…

LMS Lessons

ERIC Educational Resources Information Center

Freifeld, Lorri

2010-01-01

With technology changing every second of every day, it is no surprise a learning management system (LMS) quickly can become outdated. But it is no easy task to re-engineer a current LMS or find exactly the right new one to purchase. In this article, three 2010 Top Young Trainers share their experiences with implementing or re-engineering an…

Embedding a Learning Management System Into an Undergraduate Medical Informatics Course in Saudi Arabia: Lessons Learned

PubMed Central

2013-01-01

Background Public universities in Saudi Arabia today are making substantial investments in e-learning as part of their educational system, especially in the implementation of learning management systems (LMS). To our knowledge, this is the first study conducted in Saudi Arabia exploring medical students’ experience with an LMS, particularly as part of a medical informatics course. Objective This study investigates students’ use of various features of the LMS embedded in a recently implemented medical informatics course. Methods A mixed methodology approach was employed. Survey questionnaires were distributed to all third year medical informatics students at the end of the course. In addition, two focus group sessions were conducted with twelve students. A thematic analysis of the focus group was performed. Results A total of 265 third year medical student surveys (167/265, 63% male and 98/265, 37% female) were completed and analyzed. Overall, 50.6% (134/265) of the students agreed that the course was well planned and up-to-date, had clearly stated objectives and clear evaluation methods, appropriate course assignment, and that the LMS offered easy navigation. Most of the students rated the course as good/fair overall. In general, females were 10.4% more likely to prefer the LMS, as revealed by higher odd ratios (odds ratio [OR] 1.104, 95% CI 0.86-1.42) compared to males. Survey results showed that students’ use of LMS tools increased after taking the course compared to before taking the course. The full model containing all items were statistically significant (χ2 25=69.52, P<.001, n=243), indicating that the model was able to distinguish between students who had positive attitudes towards LMS and those who did not. The focus group, however, revealed that the students used social networking for general use rather than learning purposes, but they were using other Internet resources and mobile devices for learning. Male students showed a higher preference for using technology in general to enhance learning activities. Overall, medical student attitudes towards the LMS were generally positive. Students also wanted a reminder and notification tool to help them stay updated with course events. Interestingly, a subset of students had been running a parallel LMS of their own that has features worth exploring and could be integrated with an official LMS in the future. Conclusions To our knowledge, this was the first time that an LMS was used in a medical informatics course. Students showed interest in adapting various LMS tools to enhance their learning and gained more knowledge through familiarity with the tool. Researching an official LMS also revealed the existence of a parallel student-created LMS. This could allow teacher-led and student-led platforms to be integrated in the future for an enhanced student-centered experience. PMID:25075236

An Exploratory Investigation of Online Forum Mediated Collaborative Learning of Speech Writing: A Case Study

ERIC Educational Resources Information Center

Lata, Pushp; Luhach, Suman

2014-01-01

Learning Management Systems (LMS) are being integrated in the curriculum by many educational institutions to extend teaching and learning beyond classroom. This paper is based on a case study exploring the integration of LMS Nalanda created on Moodle in Effective Public Speaking (EPS) classroom to give students an additional platform to practice,…

The LMS Development for a Blended EFL e-Learning

ERIC Educational Resources Information Center

Okada, Takeshi; Sakamoto, Yasunobu; Sugiura, Kensuke

2014-01-01

This paper illustrates the general idea of an on-going project for the development of a new blended e-learning package for the English as a foreign language (EFL) reading instruction in Japanese universities. The authors want to draw the attention of the readers to the Learning Management System (LMS) of the package and focus on the role a new…

Designing learning management system interoperability in semantic web

NASA Astrophysics Data System (ADS)

Anistyasari, Y.; Sarno, R.; Rochmawati, N.

2018-01-01

The extensive adoption of learning management system (LMS) has set the focus on the interoperability requirement. Interoperability is the ability of different computer systems, applications or services to communicate, share and exchange data, information, and knowledge in a precise, effective and consistent way. Semantic web technology and the use of ontologies are able to provide the required computational semantics and interoperability for the automation of tasks in LMS. The purpose of this study is to design learning management system interoperability in the semantic web which currently has not been investigated deeply. Moodle is utilized to design the interoperability. Several database tables of Moodle are enhanced and some features are added. The semantic web interoperability is provided by exploited ontology in content materials. The ontology is further utilized as a searching tool to match user’s queries and available courses. It is concluded that LMS interoperability in Semantic Web is possible to be performed.

Improving the LMS Selection Process: Instructor Concerns, Usage and Perceived Value of Online Course Delivery Tools

ERIC Educational Resources Information Center

Laverty, Joseph Packy; Wood, David; Tannehill, Darcy B.; Kohun, Fred; Turchek, John

2012-01-01

Selecting or upgrading a university's Learning Management System (LMS) involves complex decisions concerning curriculum delivery, students, financial commitments, technology and support services, and faculty. The purpose of this paper is to study faculty concerns, usage and perceptions of the instructional value of online course management tools.…

The Impact of the Digital Divide on First-Year Community College Students

ERIC Educational Resources Information Center

Mansfield, Malinda

2017-01-01

Some students do not possess the learning management system (LMS) and basic computer skills needed for success in first-year experience (FYE) courses. The purpose of this quantitative study, based on the Integrative Learning Design Framework and theory of transactional distance, was to identify what basic computer skills and LMS skills are needed…

Marrying Two Existing Software Packages into an Efficient Online Tutoring Tool

ERIC Educational Resources Information Center

Byrne, Timothy

2007-01-01

Many teachers today use Learning Management Systems (LMS), several of which are open-source. Specific examples are Claroline and Moodle. However, they are not specifically designed for language learning, and hence not entirely suitable. In this article, I will compare two uses of the Claroline LMS available at Louvain-la-Neuve within the framework…

The VLE as a Trojan Mouse: Policy, Politics and Pragmatism

ERIC Educational Resources Information Center

Brown, Mark; Paewai, Shelley; Suddaby, Gordon

2010-01-01

This paper argues that selecting a new Learning Management System (LMS) is a strategic decision about the future direction of your institution. However, the development of a robust methodology for the selection of a new LMS is particularly challenging given the fluidity of the e-learning environment. This is especially so when both quantitative…

Student Perceptions of Social Presence and Attitudes toward Social Media: Results of a Cross-Sectional Study

ERIC Educational Resources Information Center

Leafman, Joan S.; Mathieson, Kathleen M.; Ewing, Helen

2013-01-01

Establishing and maintaining social presence in an online environment that depends on a learning management system (LMS) can be challenging. While students believe social presence to be important, LMS platforms have yet to discover a way to deliver this expectation. The growth of social media tools presents opportunities outside an LMS to foster…

High Enrollment Course Success Factors in Virtual School: Factors Influencing Student Academic Achievement

ERIC Educational Resources Information Center

Liu, Feng; Cavanaugh, Cathy

2011-01-01

This paper describes a study of success factors in high enrollment courses in a K-12 virtual school learning environment. The influence of variables: time student spent in the learning management system (LMS), number of times logged into the LMS, teacher comment, participation in free or reduced lunch programs, student status in the virtual school…

Evaluating Learning Management System (LMS)-facilitated Delivery of Universal Design for Learning (UDL)

NASA Astrophysics Data System (ADS)

Bryans Bongey, Sarah

This quantitative study involved 157 students in two sections of an undergraduate class in general biology, as well as one instructor who taught both sections of the course. It used resources from the Center for Applied Special Technologies (CAST) to evaluate the viability of a Learning Management System (LMS) to provide Universal Design for Learning (UDL). It also measured and tracked the instructor's level of efficacy in sustaining UDL approaches throughout the semester. In an effort to identify the UDL's specific outcomes or benefits to students, this study used a pre- and post- test to identify the treatment's impact on student engagement. Findings indicated that the LMS could be designed to comply with UDL guidelines, and the instructor was able to establish a high level of efficacy in maintaining that UDL design. However, based on the statistical analysis of pre- and post-test responses from control vs. treatment groups of students, the treatment was seen to have no significant effect in the area of student engagement. Overall, the study added to the literature by suggesting (a) the viability of the LMS as a means of providing UDL approaches, (b) the promise of the LMS as a tool faculty can use to deliver UDL with a high level of efficacy, and (c) the design's lack of effect in the area of student engagement. The fact that this study was limited to a single brand of LMS (Blackboard), a single instructor, and a single group of students underscores the need for further research.

A Comparison between LMS tools to support e-health educational activities.

PubMed

de Araújo Novaes, Magdala; Soares de Vasconcelos, Gabriel; Florencio da Silva, Jackson Raniel

2015-01-01

The objective of this study is to understand how a Learning Management System (LMS) plataform is used in a telehealth center to support two virtual learning enviroments focused on the education of the healthcare professionals and the students of a medical schoool. The study outcome is expected to provide indications towards choosing a better LSM for the telehelath center to support their educacional activities.

A Service Oriented Architecture to Integrate Mobile Assessment in Learning Management Systems

ERIC Educational Resources Information Center

Riad, A. M.; El-Ghareeb, H. A.

2008-01-01

Mobile Learning (M-Learning) is an approach to E-Learning that utilizes mobile devices. Learning Management System (LMS) should enable M-Learning. Unfortunately, M-Learning is not the same at each educational institution. Assessment is one of the learning activities that can be achieved electronically and via mobile device. Mobile assessment…

Contrasting LMS Marketing Approaches

ERIC Educational Resources Information Center

Carriere, Brain; Challborn, Carl; Moore, James; Nibourg, Theodorus

2005-01-01

The first section of this report examines the CourseCompass learning management system (LMS), made available to educators by the Pearson publishing group as a vehicle for the company's extensive content library. The product's features are discussed, and the implications of Pearson's software/textbook "bundling" policy for the integrity of course…

Web-Based Evaluation System for Learning Management Systems

ERIC Educational Resources Information Center

Momani, Alaa

2010-01-01

E-learning systems have become an issue in recent years. A learning management system (LMS) is an electronic environment helps the educational society to communicate, exchange information, manage, and schedule the learning process. This study has provided a web-based evaluation system that may help the users to choose the convenient system…

Influence of Learning Management Systems Self-Efficacy on E-Learning Performance

ERIC Educational Resources Information Center

Martin, Florence; Tutty, Jeremy I.; Su, Yuyan

2010-01-01

Recent advancements in technology have changed the way educators teach and students learn (Wells, Fieger & Lange, 2005). In the last decade, educational trends have progressed towards online and blended instruction. One key in this revolution is the development of the Learning Management System (LMS); software that enables the management and…

Toward a Student-Centered Measure of Learning Management System Utilization

ERIC Educational Resources Information Center

Malm, Eric; Defranco, Joanna F.

2012-01-01

Colleges and universities have spent significant financial and human resources deploying and promoting educational technologies, including Learning Management Systems (LMS). A large body of research now exists on the impact of technology on student learning, including the roles of blended learning, hybrid classes, and distance learning. Yet,…

Extend Instruction outside the Classroom: Take Advantage of Your Learning Management System

ERIC Educational Resources Information Center

Jensen, Lauren A.

2010-01-01

Numerous institutions of higher education have implemented a learning management system (LMS) or are considering doing so. This web-based software package provides self-service and quick (often personalized) access to content in a dynamic environment. Learning management systems support administrative, reporting, and documentation activities. LMSs…

Document-Oriented E-Learning Components

ERIC Educational Resources Information Center

Piotrowski, Michael

2009-01-01

This dissertation questions the common assumption that e-learning requires a "learning management system" (LMS) such as Moodle or Blackboard. Based on an analysis of the current state of the art in LMSs, we come to the conclusion that the functionality of conventional e-learning platforms consists of basic content management and…

Development of a Relational Database for Learning Management Systems

ERIC Educational Resources Information Center

Deperlioglu, Omer; Sarpkaya, Yilmaz; Ergun, Ertugrul

2011-01-01

In today's world, Web-Based Distance Education Systems have a great importance. Web-based Distance Education Systems are usually known as Learning Management Systems (LMS). In this article, a database design, which was developed to create an educational institution as a Learning Management System, is described. In this sense, developed Learning…

Protecting Students' Intellectual Property in the Web Plagiarism Detection Process

ERIC Educational Resources Information Center

Butakov, Sergey; Dyagilev, Vadim; Tskhay, Alexander

2012-01-01

Learning management systems (LMS) play a central role in communications in online and distance education. In the digital era, with all the information now accessible at students' fingertips, plagiarism detection services (PDS) have become a must-have part of LMS. Such integration provides a seamless experience for users, allowing PDS to check…

Mission Critical: Selecting the Right LMS

ERIC Educational Resources Information Center

Schaffhauser, Dian

2010-01-01

In the past, the learning management system (LMS) was a fairly simple program. Its job was to connect an instructor to a student for an individual course. The student could track grades without harassing the faculty member, and the professor could stop worrying about the prospect of losing a student's paper-based assignment. Often, the LMS…

Students' Perceptions of Blackboard and Moodle in a Portuguese University

ERIC Educational Resources Information Center

Carvalho, Ana; Areal, Nelson; Silva, Joaquim

2011-01-01

The use of learning management systems (LMS) has grown considerably in universities around the world. The University of Minho (UM) has pioneered in this area in Portugal, adopting Blackboard as its official LMS. Moodle is also used in UM in scattered initiatives, allowing for interesting comparisons. Previous studies comparing Blackboard and…

Mining LMS Data to Develop an "Early Warning System" for Educators: A Proof of Concept

ERIC Educational Resources Information Center

Macfadyen, Leah P.; Dawson, Shane

2010-01-01

Earlier studies have suggested that higher education institutions could harness the predictive power of Learning Management System (LMS) data to develop reporting tools that identify at-risk students and allow for more timely pedagogical interventions. This paper confirms and extends this proposition by providing data from an international…

Content Consumption and Hierarchical Structures of Web-Supported Courses

ERIC Educational Resources Information Center

Hershkovitz, Arnon; Hardof-Jaffe, Sharon; Nachmias, Rafi

2014-01-01

This study presents an empirical investigation of the relationship between the hierarchical structure of content delivered to students within a Learning Management System (LMS) and its actual consumption. To this end, campus-wide data relating to 1,203 courses were collected from the LMS' servers and were subsequently analyzed using data mining…

Validation of an Evaluation Model for Learning Management Systems

ERIC Educational Resources Information Center

Kim, S. W.; Lee, M. G.

2008-01-01

This study aims to validate a model for evaluating learning management systems (LMS) used in e-learning fields. A survey of 163 e-learning experts, regarding 81 validation items developed through literature review, was used to ascertain the importance of the criteria. A concise list of explanatory constructs, including two principle factors, was…

A Methodology to Obtain Learning Effective Laboratories with Learning Management System Integration

ERIC Educational Resources Information Center

Ruano, Ildefonso; Gamez, Javier; Dormido, Sebastian; Gomez, Juan

2016-01-01

Online laboratories are useful and valuable resources in high education, especially in engineering studies. This work presents a methodology to create effective laboratories for learning that interact with a Learning Management System (LMS) to achieve advanced integration. It is based on pedagogical aspects and considers not only the laboratory…

Experiences with establishing and implementing learning management system and computer-based test system in medical college.

PubMed

Park, Joo Hyun; Son, Ji Young; Kim, Sun

2012-09-01

The purpose of this study was to establish an e-learning system to support learning in medical education and identify solutions for improving the system. A learning management system (LMS) and computer-based test (CBT) system were established to support e-learning for medical students. A survey of 219 first- and second-grade medical students was administered. The questionnaire included 9 forced choice questions about the usability of system and 2 open-ended questions about necessary improvements to the system. The LMS consisted of a class management, class evaluation, and class attendance system. CBT consisted of a test management, item bank, and authoring tool system. The results of the survey showed a high level of satisfaction in all system usability items except for stability. Further, the advantages of the e-learning system were ensuring information accessibility, providing constant feedback, and designing an intuitive interface. Necessary improvements to the system were stability, user control, readability, and diverse device usage. Based on the findings, suggestions for developing an e-learning system to improve usability by medical students and support learning effectively are recommended.

Moodle as a Learning Environment in Promoting Conceptual Understanding for Secondary School Students

ERIC Educational Resources Information Center

Psycharis, Sarantos; Chalatzoglidis, Georgios; Kalogiannakis, Michail

2013-01-01

The purpose of this study was to investigate the role of e-learning, as a pedagogical tool, for changing initial conceptions when learning about physics by using the learning management System of the Moodle platform. Our study provides an empirical exploration of the pedagogical use of Moodle Learning Management System (LMS) in order to…

Nextgen Navy eLearning Tracking

DTIC Science & Technology

2014-12-01

ELEARNING TRACKING by William E. Miller December 2014 Thesis Advisor: Man-Tak Shing Co-Advisor: Arijit Das THIS PAGE INTENTIONALLY LEFT......Navy’s eLearning (NeL) computer-based learning system relies on a Learning Management System (LMS) for content delivery and tracking learning

Course Evaluation: Reconfigurations for Learning with Learning Management Systems

ERIC Educational Resources Information Center

Park, Ji Yong

2014-01-01

The introduction of online delivery platforms such as learning management systems (LMS) in tertiary education has changed the methods and modes of curriculum delivery and communication. While course evaluation methods have also changed from paper-based in-class-administered methods to largely online-administered methods, the data collection…

Design and Effects of a Concept Focused Discussion Environment in E-Learning

ERIC Educational Resources Information Center

Yilmaz, Erdi Okan; Yurdugul, Halil

2016-01-01

Problem Statement: Within the frame of learning management systems, this study develops a concept focused discussion environment and validates the effectiveness of this environment's use through an experimental study. Purpose of the Study: Online discussion forums, which are commonly used in learning management systems (LMS), can negatively…

Improving Assessment Processes in Higher Education: Student and Teacher Perceptions of the Effectiveness of a Rubric Embedded in a LMS

ERIC Educational Resources Information Center

Atkinson, Doug; Lim, Siew Leng

2013-01-01

Students and teachers play different roles and thus have different perceptions about the effectiveness of assessment including structure, feedback, consistency, fairness and efficiency. In an undergraduate Business Information Systems course, a rubric was designed and semi-automated through a learning management system (LMS) to provide formative…

Web-Education Systems in Europe. ZIFF Papiere.

ERIC Educational Resources Information Center

Paulsen, Morten; Keegan, Desmond; Dias, Ana; Dias, Paulo; Pimenta, Pedro; Fritsch, Helmut; Follmer, Holger; Micincova, Maria; Olsen, Gro-Anett

This document contains the following papers on Web-based education systems in Europe: (1) "European Experiences with Learning Management Systems" (Morten Flate Paulsen and Desmond Keegan); (2) "Online Education Systems: Definition of Terms" (Morten Flate Paulsen); (3) "Learning Management Systems (LMS) Used in Southern…

Learning Management System Calendar Reminders and Effects on Time Management and Academic Performance

ERIC Educational Resources Information Center

Mei, Jianyang

2016-01-01

This research project uses a large research university in the Midwest as a research site to explore the time management skills of international students and analyzes how using the Course Hack, an online Learning Management System (LMS) calendar tool, improves participants' time management skills and positively impacts their academic performance,…

Assessing the Efficacy of Incorporating Game Dynamics in a Learning Management System

ERIC Educational Resources Information Center

Frost, Raymond D.; Matta, Vic; MacIvor, Erin

2015-01-01

The goal of the study was to see if gamification of a Learning Management System (LMS) would increase a number of desirable outcomes: student interest, motivation, satisfaction, student learning and perception of pedagogical affect. These constructs were measured in a survey, except for learning, which was measured by grades. Gamification of the…

Student and Staff Perceptions of a Learning Management System for Blended Learning in Teacher Education

ERIC Educational Resources Information Center

Holmes, Kathryn A.; Prieto-Rodriguez, Elena

2018-01-01

Higher education institutions routinely use Learning Management Systems (LMS) for multiple purposes; to organise coursework and assessment, to facilitate staff and student interactions, and to act as repositories of learning objects. The analysis reported here involves staff (n = 46) and student (n = 470) responses to surveys as well as data…

Students' Learning Behavior, Motivation and Critical Thinking in Learning Management Systems

ERIC Educational Resources Information Center

Wichadee, Saovapa

2014-01-01

Computer mediated communication (CMC) offers new opportunities for learners to create communities of inquiry that allow for more active learning. This paper reports on the use of a Learning Management System (LMS) as a tool to facilitate students' writing and critical thinking skills. The primary data for the study came from students'…

A Qualitative Study on Learning and Teaching with Learning Paths in a Learning Management System

ERIC Educational Resources Information Center

De Smet, Cindy; Valcke, Martin; Schellens, Tammy; De Wever, Bram; Vanderlinde, Ruben

2016-01-01

This article presents the findings of a qualitative study (carried out between 2011 and 2013) about the adoption and implementation of learning paths within a Learning Management System (LMS). Sixteen secondary school biology teachers of the GO! Network in Flanders (an urbanized region in Belgium) were involved in the study and questioned via…

On the Use of Extended TAM to Assess Students' Acceptance and Intent to Use Third-Generation Learning Management Systems

ERIC Educational Resources Information Center

Ros, Salvador; Hernández, Roberto; Caminero, Agustín; Robles, Antonio; Barbero, Isabel; Maciá, Araceli; Holgado, Francisco Pablo

2015-01-01

Service-oriented e-learning platforms can be considered as a third generation of learning management systems (LMSs). As opposed to the previous generations, consisting of ad hoc solutions and traditional LMS, this new technology contemplates e-learning systems as services that can be integrated into different learning scenarios. This paper shows…

B-Learning under Examination: Advantages, Disadvantages and Opinions

ERIC Educational Resources Information Center

Bemposta-Rosende, Sergio; García-García, María José; Escribano-Otero, Juan José

2011-01-01

In recent years, learning management systems (LMS) have become very popular in almost all traditional universities, generating a new learning strategy approach, mixing elements from both traditional and online learning: the blended learning or b-learning. How these new environments influence teaching activities and learning processes are the main…

The Influences of Technical Support, Self Efficacy and Instructional Design on the Usage and Acceptance of LMS: A Comprehensive Review

ERIC Educational Resources Information Center

Alshammari, Sultan Hammad; Ali, Mohamad Bilal; Rosli, Mohd Shafie

2016-01-01

Innovation, globalization and the rapid expansion of technologies are the current trend now, which lead to the use of latest technologies in several different sectors, including education sector without exception. Learning management system (LMS) that is used for delivering education has become one of the most important innovative tools that is…

NEW TRAINING PARADIGM IN THE NATIONAL WEATHER SERVICE LeRoy Spayd Chief, Training Division NOAA/National Weather Service Silver Spring, Maryland

NASA Astrophysics Data System (ADS)

Spayd, L. E.

2012-12-01

The National Weather Service (NWS) implemented a new Learning Management System (LMS) in June 2007 as part of a Department of Commerce (DOC)-wide Learning Center (CLC). One of the key goals of this LMS was to provide accessible, low-cost training to develop and sustain a world-class NOAA workforce. Five years of training records have been analyzed for trends and accomplishments have been summarized. The NWS leads the entire DOC in usage of this LMS. NWS workforce of 4500 employees complete over 50,000 courses per year and account for over 40% of DOC completions even though the NWS represents only 12% of the users. This paper will highlight the lessons learned in implementing training in a diverse and widespread organization. The paper will also highlight the critical role of management engagement in setting expectations for training and education which resulted in service improvements to the public. This paper also address future training trends as the NWS moves forward in implementing NOAA's Strategic Plan to make this country a WeatherReady Nation. A mix of how synchronous/asynchronous and classroom/on-line/hybrid learning options is explained.;

Academic perceptions amongst educators towards eLearning tools in dental education.

PubMed

Handal, Boris; Groenlund, Catherine; Gerzina, Tania

2011-04-01

This paper reports an explorative study about academic educators' perceptions towards learning management systems (LMS) and eLearning tools as used in dental education. Fifty-five educators participated in an online survey which explored their views on eLearning tools within the context of their own professional training background and teaching needs. In general, educators felt that the eLearning LMS (also known as WebCT/Blackboard) was a tool that suited their teaching and learning needs in terms of flexibility, interactivity and accessibility despite a significant level of self-reported lack of competence in the technology. The paper describes current eLearning professional development initiatives in light of these findings. © 2011 FDI World Dental Federation.

Initial Perceptions of Open Higher Education Students with Learner Management Systems

ERIC Educational Resources Information Center

Altunoglu, Asu

2017-01-01

Learner management systems (LMS) are used in open education as a means of managing and recording e-learning facilities as well as improving student engagement. Students benefit from them to become active participants in the decision-making process of their own learning. This study aims to investigate the initial perceptions of students…

Personalized Virtual Learning Environment from the Detection of Learning Styles

ERIC Educational Resources Information Center

Martínez Cartas, M. L.; Cruz Pérez, N.; Deliche Quesada, D.; Mateo Quero, S.

2013-01-01

Through the previous detection of existing learning styles in a classroom, a Virtual Learning Environment (VLE) has been designed for students of several Engineering degrees, using the Learning Management System (LMS) utilized in the University of Jaen, ILIAS. Learning styles of three different Knowledge Areas; Chemical Engineering, Materials…

Identifying Successful Learners from Interaction Behaviour

ERIC Educational Resources Information Center

McCuaig, Judi; Baldwin, Julia

2012-01-01

The interaction behaviours of successful, high-achieving learners when using a Learning Management System (LMS) are different than the behaviours of learners who are having more difficulty mastering the course material. This paper explores the idea that conventional Learning Management Systems can exploit data mining techniques to predict the…

Drivers of Learning Management System Use in a South African Open and Distance Learning Institution

ERIC Educational Resources Information Center

Venter, Peet; van Rensburg, Mari Jansen; Davis, Annemarie

2012-01-01

The study on which this article reports examined the determinants of usage of an online learning management system (LMS) by fourth level business students at a South African open and distance learning university using an extension of the widely used technology acceptance model (TAM) as a theoretical basis. A survey was conducted among students at…

Using the Facebook Group as a Learning Management System: An Exploratory Study

ERIC Educational Resources Information Center

Wang, Qiyun; Woo, Huay Lit; Quek, Choon Lang; Yang, Yuqin; Liu, Mei

2012-01-01

Facebook is a popular social networking site. It, like many other new technologies, has potential for teaching and learning because of its unique built-in functions that offer pedagogical, social and technological affordances. In this study, the Facebook group was used as a learning management system (LMS) in two courses for putting up…

Policies on and Practices of Cultural Inclusivity in Learning Management Systems: Perspectives of Indigenous Holistic Pedagogies

ERIC Educational Resources Information Center

Dreamson, Neal; Thomas, Gary; Lee Hong, Anita; Kim, Soyoung

2017-01-01

Online learning has become a conventional term and practice in Australian higher education, yet cultural inclusivity for Indigenous (Indigenous for the purposes of this paper refers to Australian Aboriginal and Torres Strait Islander peoples) students is insufficiently reflected in learning management system (LMS) policies and design. This study…

Practice and Repetition during Exam Preparation in Blended Learning Courses: Correlations with Learning Results

ERIC Educational Resources Information Center

Andergassen, Monika; Mödritscher, Felix; Neumann, Gustaf

2014-01-01

Learner-centric research on factors influencing learning results has focused, among other things, on student characteristics, demographic data, and usage patterns in learning management systems (LMSs). This paper complements the existing research by investigating potential correlations between learning results and LMS usage during exam…

Mobile Authoring of Open Educational Resources as Reusable Learning Objects

ERIC Educational Resources Information Center

Kinshuk; Jesse, Ryan

2013-01-01

E-learning technologies have allowed authoring and playback of standardized reusable learning objects (RLO) for several years. Effective mobile learning requires similar functionality at both design time and runtime. Mobile devices can play RLO using applications like SMILE, mobile access to a learning management system (LMS), or other systems…

Using Learning Management Systems in Business and Economics Studies in Hungarian Higher Education

ERIC Educational Resources Information Center

Nagy, Judit T.

2016-01-01

This paper explores all uses of LMS in teaching Business Mathematics in Hungarian undergraduate training from the point of view of the instructors. Since no similar survey had been carried out in Hungary earlier, the aim was to fill in this gap and to investigate which LMS systems are being used by the instructors, to what specific purposes and…

Finding Support in Moodle: A Face-to-Face Chemistry Course for Engineers

ERIC Educational Resources Information Center

de Vega, Carolina Armijo; McAnally-Salas, Lewis

2011-01-01

The aim of this paper was to know the students' perceptions of using online support in a chemistry course. To achieve this objective, a qualitative research was conducted over a chemistry course that was imparted in a face-to-face modality using a LMS (learning management system) for on-line support. The supports available in the LMS were forums,…

The development of a learning management system for dental radiology education: A technical report.

PubMed

Chang, Hee-Jin; Symkhampha, Khanthaly; Huh, Kyung-Hoe; Yi, Won-Jin; Heo, Min-Suk; Lee, Sam-Sun; Choi, Soon-Chul

2017-03-01

This study was conducted to suggest the development of a learning management system for dental radiology education using the Modular Object-Oriented Dynamic Learning Environment (Moodle). Moodle is a well-known and verified open-source software-learning management system (OSS-LMS). The Moodle software was installed on a server computer and customized for dental radiology education. The system was implemented for teaching undergraduate students to diagnose dental caries in panoramic images. Questions were chosen that could assess students' diagnosis ability. Students were given several questions corre-sponding to each of 100 panoramic images. The installation and customization of Moodle was feasible, cost-effective, and time-saving. By having students answer questions repeatedly, it was possible to train them to examine panoramic images sequentially and thoroughly. Based on its educational efficiency and efficacy, the adaptation of an OSS-LMS in dental school may be highly recommended. The system could be extended to continuing education for dentists. Further studies on the objective evaluation of knowledge acquisition and retention are needed.

Implementing Collaborative Design in the Next Series of eLearning Platforms

ERIC Educational Resources Information Center

Kropf, Dorothy

2013-01-01

Collaborative design empowers learning management system (LMS) providers and end users (online students) to develop a vibrant teaching and learning community. Successful periodic collaborations utilizing collaborative web tools between these two pivotal groups can produce the next series of eLearning platforms that are fertile grounds for…

I Can Make a Scientific Research: A Course about Scientific Research Methods, in Which Learning Management System (LMS) Is Used

ERIC Educational Resources Information Center

Özden, Bülent

2016-01-01

The purpose of this study was to determine the changes in the perception of teacher candidates towards scientific research process and their self-efficacy in this process, during Scientific Research Methods course that has been conducted using "Learning Management System" based on out-of-class learning activities. Being designed as a…

Moodle 2.0: Shifting from a Learning Toolkit to a Open Learning Platform

NASA Astrophysics Data System (ADS)

Alier, Marc; Casañ, María José; Piguillem, Jordi

Learning Management Systems (LMS) have reached a plateau of maturity in features, application to teaching practices and wide adoption by learning institutions. But the Web 2.0 carries new kinds of tools, services and ways of using the web; personally and socially. Some educators and learners have started to advocate for a new approach to frame one's learning sources, from the LMS course space towards Personal Learning Environments (PLE). But PLE's are characterized by its absence of structure, just what is provided by open standards and mashup techniques. Based on 5 years of participative observation research, this article explains the changes in architecture performed on the second version of Moodle, why did these changes happen and what should be the next steps so Moodle can shift from being a learning tool to a true open learning platform.

A New Method for Measuring Text Similarity in Learning Management Systems Using WordNet

ERIC Educational Resources Information Center

Alkhatib, Bassel; Alnahhas, Ammar; Albadawi, Firas

2014-01-01

As text sources are getting broader, measuring text similarity is becoming more compelling. Automatic text classification, search engines and auto answering systems are samples of applications that rely on text similarity. Learning management systems (LMS) are becoming more important since electronic media is getting more publicly available. As…

Open-Source Learning Management Systems: A Predictive Model for Higher Education

ERIC Educational Resources Information Center

van Rooij, S. Williams

2012-01-01

The present study investigated the role of pedagogical, technical, and institutional profile factors in an institution of higher education's decision to select an open-source learning management system (LMS). Drawing on the results of previous research that measured patterns of deployment of open-source software (OSS) in US higher education and…

Use and Attitude towards Learning Management Systems (LMS) in Saudi Arabian Universities

ERIC Educational Resources Information Center

Alghamdi, Saleh Ramadhan; Bayaga, Anass

2016-01-01

This paper was designed to establish the relationships between faculty members' use and attitude towards Learning Management Systems (LMSs). LMSs have been adopted in various educational institutions due to their numerous applications and functionalities to improve pedagogy. As a result, faculty members are urged to utilise them for enhancing…

Accessibility Evaluation of Online Learning Management System for Persons with Visual Impairment

ERIC Educational Resources Information Center

Suwannawut, Nantanoot

2014-01-01

Many academic institutions around the world are utilizing and investing in online learning management systems (LMS). While several research studies have examined the functionality of this type of technology, little attention has been paid to accessibility issues, in particular to the complex web-based interfaces for learners with disabilities,…

Designing Mobile LMS Interfaces: Learners' Expectations and Experiences

ERIC Educational Resources Information Center

Ssekakubo, Grace; Suleman, Hussein; Marsden, Gary

2013-01-01

Purpose: This paper aims to present findings of a study that was carried out to identify strategies of enabling learners in developing countries to fully exploit the potential of learning management systems (LMSs). The study set out to: identify the services of learning management systems that are most needed and desired by university learners in…

Evaluation of Online Log Variables That Estimate Learners' Time Management in a Korean Online Learning Context

ERIC Educational Resources Information Center

Jo, Il-Hyun; Park, Yeonjeong; Yoon, Meehyun; Sung, Hanall

2016-01-01

The purpose of this study was to identify the relationship between the psychological variables and online behavioral patterns of students, collected through a learning management system (LMS). As the psychological variable, time and study environment management (TSEM), one of the sub-constructs of MSLQ, was chosen to verify a set of time-related…

Towards Actionable Learning Analytics Using Dispositions

ERIC Educational Resources Information Center

Tempelaar, Dirk T.; Rienties, Bart; Nguyen, Quan

2017-01-01

Studies in the field of learning analytics (LA) have shown students' demographics and learning management system (LMS) data to be effective identifiers of "at risk" performance. However, insights generated by these predictive models may not be suitable for pedagogically informed interventions due to the inability to explain why students…

A Service-oriented Approach towards Context-aware Mobile Learning Management Systems

DTIC Science & Technology

2010-07-01

towards a pervasive university. Keywords-context-aware computing, service-oriented archi- tecture, mobile computing, elearning , learn management sys- tem I...usage of device- specific features provide support for various ubiquitous and pervasive eLearning scenarios [2][3]. By knowing where the user currently...data from the mobile device towards a context-aware mobile LMS. II. BASIC CONCEPTS For a better understanding of the presented eLearning sce- narios

The Use of Social Networking and Learning Management Systems in English Language Teaching in Higher Education

ERIC Educational Resources Information Center

Dogoriti, Evriklea; Pange, Jenny; Anderson, Gregory S.

2014-01-01

Purpose: The use of web-enhanced teaching of the English as a foreign language in higher education in Greece is addressed in this case study which examines the student's perceptions of online instruction using Moodle as a learning management system (LMS), with and without the use of Facebook (FB) as an adjunctive learning platform. The merging of…

Benefits and Barriers of E-Learning for Staff Training in a Medical University.

PubMed

Franz, Stefan; Behrends, Marianne; Haack, Claudia; Marschollek, Michael

2015-01-01

Learning Management Systems (LMS) are a feasible solution to fulfill the various requirements for e-learning based training in a medical university. Using the LMS ILIAS, the Institute of Diagnostic and Interventional Radiology has designed an e-learning unit about data protection, which has been used by 73% of the department's employees in the first three months. To increase the use of e-learning for staff training, it is necessary to identify barriers and benefits, which encourage the use of e-learning. Therefore, we started an online survey to examine how the employees evaluate this learning opportunity. The results show that 87% of the employees had no technical problems and also competence of Information and Communication Technology (ICT) was no barrier. If anything, reported issues were time shortages and tight schedules. Therefore, short learning modules (less than 20 minutes) are preferred. Furthermore, temporal flexibility for learning is important for 83% of employees.

An Ensemble Approach in Converging Contents of LMS and KMS

ERIC Educational Resources Information Center

Sabitha, A. Sai; Mehrotra, Deepti; Bansal, Abhay

2017-01-01

Currently the challenges in e-Learning are converging the learning content from various sources and managing them within e-learning practices. Data mining learning algorithms can be used and the contents can be converged based on the Metadata of the objects. Ensemble methods use multiple learning algorithms and it can be used to converge the…

Moving beyond Blackboard: Using a Social Network as a Learning Management System

ERIC Educational Resources Information Center

Thacker, Christopher

2012-01-01

Web 2.0 is a paradigm of a participatory Internet, which has implications for the delivery of online courses. Instructors and students can now develop, distribute, and aggregate content through the use of third-party web applications, particularly social networking platforms, which combine to form a user-created learning management system (LMS).…

Using Compositional Writing Samples to Explore Student Usage Patterns in a Learning Management System

ERIC Educational Resources Information Center

Kokensparger, Brian Jay

2013-01-01

This study explored relationships between writing sample features and LMS usage patterns for 366 college students who enrolled in Theology courses, junior-level courses cross-listed with theology courses, or Senior Perspective Program courses in the fall semester of 2012. These hybrid courses were managed inside the Canvas(TM) learning management…

Antecedents of Continued Usage Intentions of Web-Based Learning Management System in Tanzania

ERIC Educational Resources Information Center

Lwoga, Edda Tandi; Komba, Mercy

2015-01-01

Purpose: The purpose of this paper is to examine factors that predict students' continued usage intention of web-based learning management systems (LMS) in Tanzania, with a specific focus on the School of Business of Mzumbe University. Specifically, the study investigated major predictors of actual usage and continued usage intentions of…

Pre-Service Teachers' Lived Experiences with Taking Courses through Learning Management Systems: A Qualitative Study

ERIC Educational Resources Information Center

Ergul Sonmez, Esra; Koc, Mustafa

2018-01-01

Learning management systems (LMS) are web-based platforms used for enhancing and supporting classroom teaching or delivering online instruction. Much of the earlier research has focused on their technological features and implementations into instruction. However, investigating what and how teachers and students think about and experience with LMS…

Free Choice of Learning Management Systems: Do Student Habits Override Inherent System Quality?

ERIC Educational Resources Information Center

Porter, Gavin W.

2013-01-01

Purpose: Although multiple studies examine institutional transitions of learning management systems (LMS) or compare their merits, studies examining students' free choice of access on parallel LMSs for the same course are absent from the literature. In order to investigate usage in a free-choice situation, identical content was posted at the same…

Facebook as a Learning-Management System in Developmental Writing

ERIC Educational Resources Information Center

Ingalls, Amy L.

2017-01-01

The purpose of this study was to assess whether Facebook (FB), as an LMS (Learning Management System) may be used in a developmental writing course, may build a community of learners in ENG*K012, and may enhance the presence of a supportive shared community to build confidence in students' writing and/or sharing their writing. An additional…

Implementing an Open Source Learning Management System: A Critical Analysis of Change Strategies

ERIC Educational Resources Information Center

Uys, Philip M.

2010-01-01

This paper analyses the change and innovation strategies that Charles Sturt University (CSU) used from 2007 to 2009 during the implementation and mainstreaming of an open source learning management system (LMS), Sakai, named locally as "CSU Interact". CSU was in January 2008 the first Australian University to implement an open source…

Factors Influencing the Use of Learning Management System in Saudi Arabian Higher Education: A Theoretical Framework

ERIC Educational Resources Information Center

Asiri, Mohammed J. Sherbib; Mahmud, Rosnaini bt; Bakar, Kamariah Abu; Ayub, Ahmad Fauzi bin Mohd

2012-01-01

The purpose of this paper is to present the theoretical framework underlying a research on factors that influence utilization of the Jusur Learning Management System (Jusur LMS) in Saudi Arabian public universities. Development of the theoretical framework was done based on library research approach. Initially, the existing literature relevant to…

Design and Delivery of Online Courses in YCMOU

ERIC Educational Resources Information Center

Kamlaskar, Chetana H.; Killedar, Manoj

2015-01-01

The School of Science and Technology of "Yashwantrao Chavan Maharashtra Open University (YCMOU)" has proposed to offer "Web Based Live Teaching Learning Support" from "real" teacher, with "Live Virtual Online Class (LVOC)" integrated with "Learning Management System (LMS)" for all courses of all…

Statistical efficiency of adaptive algorithms.

PubMed

Widrow, Bernard; Kamenetsky, Max

2003-01-01

The statistical efficiency of a learning algorithm applied to the adaptation of a given set of variable weights is defined as the ratio of the quality of the converged solution to the amount of data used in training the weights. Statistical efficiency is computed by averaging over an ensemble of learning experiences. A high quality solution is very close to optimal, while a low quality solution corresponds to noisy weights and less than optimal performance. In this work, two gradient descent adaptive algorithms are compared, the LMS algorithm and the LMS/Newton algorithm. LMS is simple and practical, and is used in many applications worldwide. LMS/Newton is based on Newton's method and the LMS algorithm. LMS/Newton is optimal in the least squares sense. It maximizes the quality of its adaptive solution while minimizing the use of training data. Many least squares adaptive algorithms have been devised over the years, but no other least squares algorithm can give better performance, on average, than LMS/Newton. LMS is easily implemented, but LMS/Newton, although of great mathematical interest, cannot be implemented in most practical applications. Because of its optimality, LMS/Newton serves as a benchmark for all least squares adaptive algorithms. The performances of LMS and LMS/Newton are compared, and it is found that under many circumstances, both algorithms provide equal performance. For example, when both algorithms are tested with statistically nonstationary input signals, their average performances are equal. When adapting with stationary input signals and with random initial conditions, their respective learning times are on average equal. However, under worst-case initial conditions, the learning time of LMS can be much greater than that of LMS/Newton, and this is the principal disadvantage of the LMS algorithm. But the strong points of LMS are ease of implementation and optimal performance under important practical conditions. For these reasons, the LMS algorithm has enjoyed very widespread application. It is used in almost every modem for channel equalization and echo cancelling. Furthermore, it is related to the famous backpropagation algorithm used for training neural networks.

Quantitative Aspects about the Interactions of Professors in the Learning Management System during a Final Undergraduate Project Distance Discipline

ERIC Educational Resources Information Center

Cechinel, Cristian

2014-01-01

This work presents a quantitative study of the use of a Learning Management System (LMS) by the professors of a distance learning course, focused on the guidance given for the students' Final Undergraduate Project. Data taken from the logs of 34 professors in two distinct virtual rooms were collected. After pre-processing the data, a series of…

Fostering a Web 2.0 Ethos in a Traditional e-Learning Environment

ERIC Educational Resources Information Center

Martin, Marie; Noakes, Michaela

2012-01-01

As technology continues to flatten the world and as Web 2.0 changes the way knowledge is created and shared, tertiary education institutions are turning increasingly to e-learning to extend access to students globally as well as to improve the quality of their learning experience. Learning Management Systems (LMS) currently dominate the delivery…

Does Time-on-Task Estimation Matter? Implications for the Validity of Learning Analytics Findings

ERIC Educational Resources Information Center

Kovanovic, Vitomir; Gaševic, Dragan; Dawson, Shane; Joksimovic, Srecko; Baker, Ryan S.; Hatala, Marek

2015-01-01

With\twidespread adoption of Learning Management Systems (LMS) and other learning technology, large amounts of data--commonly known as trace data--are readily accessible to researchers. Trace data has been extensively used to calculate time that students spend on different learning activities--typically referred to as time-on-task. These measures…

Utilizing the Active and Collaborative Learning Model in the Introductory Physics Course

ERIC Educational Resources Information Center

Nam, Nguyen Hoai

2014-01-01

Model of active and collaborative learning (ACLM) applied in training specific subject makes clear advantage due to the goals of knowledge, skills that students got to develop successful future job. The author exploits the learning management system (LMS) of Hanoi National University of Education (HNUE) to establish a learning environment in the…

The Development of a Learning Dashboard for Lecturers: A Case Study on a Student-Centered E-Learning Environment

ERIC Educational Resources Information Center

Santoso, Harry B.; Batuparan, Alivia Khaira; Isal, R. Yugo K.; Goodridge, Wade H.

2018-01-01

Student Centered e-Learning Environment (SCELE) is a Moodle-based learning management system (LMS) that has been modified to enhance learning within a computer science department curriculum offered by the Faculty of Computer Science of large public university in Indonesia. This Moodle provided a mechanism to record students' activities when…

The Intentional Use of Learning Management Systems (LMS) to Improve Outcomes in Studio

ERIC Educational Resources Information Center

MacKenzie, Andrew; Muminovic, Milica; Oerlemans, Karin

2017-01-01

At the University of Canberra, Australia, the design and architecture faculty are trialling a range of approaches to incorporating learning technologies in the first year foundation studio to improve student learning outcomes. For this study researchers collected information on students' access to their assignment information and feedback from the…

Methods and Frequency of Sharing of Learning Resources by Medical Students

ERIC Educational Resources Information Center

Judd, Terry; Elliott, Kristine

2017-01-01

University students have ready access to quality learning resources through learning management systems (LMS), online library collections and generic search tools. However, anecdotal evidence suggests they sometimes turn to peer-based sharing rather than sourcing resources directly. We know little about this practice--how common it is, what sort…

"The Evolution of e-Learning in the Context of 3D Virtual Worlds"

ERIC Educational Resources Information Center

Kotsilieris, Theodore; Dimopoulou, Nikoletta

2013-01-01

Information and Communication Technologies (ICT) offer new approaches towards knowledge acquisition and collaboration through distance learning processes. Web-based Learning Management Systems (LMS) have transformed the way that education is conducted nowadays. At the same time, the adoption of Virtual Worlds in the educational process is of great…

Student Usage of Instructional Technologies: Differences in Online Learning Styles

ERIC Educational Resources Information Center

Ballenger, Robert M.; Garvis, Dennis M.

2010-01-01

We contribute to the MIS education literature by empirically examining Web log server data generated by undergraduate students enrolled in multiple sections of a MIS course where an online Learning Management System (LMS) was used to complement a traditional classroom environment. We identify online learning styles by investigating differences in…

Enhancing Learning Management Systems Utility for Blind Students: A Task-Oriented, User-Centered, Multi-Method Evaluation Technique

ERIC Educational Resources Information Center

Babu, Rakesh; Singh, Rahul

2013-01-01

This paper presents a novel task-oriented, user-centered, multi-method evaluation (TUME) technique and shows how it is useful in providing a more complete, practical and solution-oriented assessment of the accessibility and usability of Learning Management Systems (LMS) for blind and visually impaired (BVI) students. Novel components of TUME…

An Open IMS-Based User Modelling Approach for Developing Adaptive Learning Management Systems

ERIC Educational Resources Information Center

Boticario, Jesus G.; Santos, Olga C.

2007-01-01

Adaptive LMS have not yet reached the eLearning marketplace due to methodological, technological and management open issues. At aDeNu group, we have been working on two key challenges for the last five years in related research projects. Firstly, develop the general framework and a running architecture to support the adaptive life cycle (i.e.,…

A Comparison of Learning Management Systems in a School District: Searching for the Ideal Personalized Integrated Educational System (PIES)

ERIC Educational Resources Information Center

Yildirim, Zahide; Reigeluth, Charles M.; Kwon, Seolim; Kageto, Yuichi; Shao, Zihang

2014-01-01

This study explored the use of several learning management systems (LMS), their benefits, and their limitations in relation to the desired characteristics of an ideal Personalized Integrated Educational System (PIES) for the information age. A qualitative research design was used. The participants of the study were teachers, administrators, and…

Developmental English Professors' Experiences with Learning Management Systems at an Urban Community College: Challenges, Benefits, and Other Perceptions

ERIC Educational Resources Information Center

Lewis, Amy L.

2016-01-01

Universities and colleges are embracing and utilizing technology to a rapidly increasing extent, responding to its cost-effectiveness and efficiency as well as the regularity with which 21st century students rely upon it in their everyday lives. Chief amongst the technology used in higher education are Learning Management Systems (LMS), such as…

Comparison between Two Learning Management Systems: Moodle and Blackboard

ERIC Educational Resources Information Center

Momani, Alaa M.

2010-01-01

Moodle and Blackboard are two of the most famous and widely-known Learning Management Systems (LMS) over the world especially in the universities and other educational organizations. They have lots in common, but also have some key differences which make each one special in its own way. We note these differences below. If you have used any one of…

Corporate knowledge repository: Adopting academic LMS into corporate environment

NASA Astrophysics Data System (ADS)

Bakar, Muhamad Shahbani Abu; Jalil, Dzulkafli

2017-10-01

The growth of Knowledge Economy has transformed human capital to be the vital asset in business organization of the 21st century. Arguably, due to its white-collar nature, knowledge-based industry is more favorable than traditional manufacturing business. However, over dependency on human capital can also be a major challenge as any workers will inevitably leave the company or retire. This situation will possibly create knowledge gap that may impact business continuity of the enterprise. Knowledge retention in the corporate environment has been of many research interests. Learning Management System (LMS) refers to the system that provides the delivery, assessment and management tools for an organization to handle its knowledge repository. By using the aspirations of a proven LMS implemented in an academic environment, this paper proposes LMS model that can be used to enable peer-to-peer knowledge capture and sharing in the knowledge-based organization. Cloud Enterprise Resource Planning (ERP), referred to an ERP solution in the internet cloud environment was chosen as the domain knowledge. The complexity of the Cloud ERP business and its knowledge make it very vulnerable to the knowledge retention problem. This paper discusses how the company's essential knowledge can be retained using the LMS system derived from academic environment into the corporate model.

Gamification in Blackboard Learn

ERIC Educational Resources Information Center

Machajewski, Szymon

2017-01-01

Gamification is an important movement in business management, but also in higher education. Projects like the GradeCraft LMS, funded at $1.8 million dollars at U of M, demonstrate that designing student experience in learning is a top priority for major educational institutions. Considering enrollment limitations and changes in population…

Educational Knowledge Generation from Administrative Data

ERIC Educational Resources Information Center

Arevalillo-Herraez, Miguel; Moreno-Clari, Paloma; Cerveron-Lleo, Vicente

2011-01-01

Most universities use Information Systems (IS) to perform their daily administrative activities (student enrollment, data files, accountancy, etc.), and an integrated Learning Management System (LMS) to support teaching and learning. However, although a lot of effort has been put into deploying these computerized systems, the data that they…

Extending LMS to Support IRT-Based Assessment Test Calibration

NASA Astrophysics Data System (ADS)

Fotaris, Panagiotis; Mastoras, Theodoros; Mavridis, Ioannis; Manitsaris, Athanasios

Developing unambiguous and challenging assessment material for measuring educational attainment is a time-consuming, labor-intensive process. As a result Computer Aided Assessment (CAA) tools are becoming widely adopted in academic environments in an effort to improve the assessment quality and deliver reliable results of examinee performance. This paper introduces a methodological and architectural framework which embeds a CAA tool in a Learning Management System (LMS) so as to assist test developers in refining items to constitute assessment tests. An Item Response Theory (IRT) based analysis is applied to a dynamic assessment profile provided by the LMS. Test developers define a set of validity rules for the statistical indices given by the IRT analysis. By applying those rules, the LMS can detect items with various discrepancies which are then flagged for review of their content. Repeatedly executing the aforementioned procedure can improve the overall efficiency of the testing process.

Comparing Learning Outcomes of Video-Based E-Learning with Face-to-Face Lectures of Agricultural Engineering Courses in Korean Agricultural High Schools

ERIC Educational Resources Information Center

Park, Sung Youl; Kim, Soo-Wook; Cha, Seung-Bong; Nam, Min-Woo

2014-01-01

This study investigated the effectiveness of e-learning by comparing the learning outcomes in conventional face-to-face lectures and e-learning methods. Two video-based e-learning contents were developed based on the rapid prototyping model and loaded onto the learning management system (LMS), which was available at http://www.greenehrd.com.…

The Important Elements of LMS Design That Affect User Engagement with E-Learning Tools within LMSs in the Higher Education Sector

ERIC Educational Resources Information Center

Zanjani, Nastaran; Edwards, Sylvia L.; Nykvist, Shaun; Geva, Shlomo

2017-01-01

In recent years, universities have been under increased pressure to adopt e-learning practices for teaching and learning. In particular, the emphasis has been on learning management systems (LMSs) and associated collaboration tools to provide opportunities for sharing knowledge, building a community of learners, and supporting higher order…

The Hybrid Studio--Introducing Google+ as a Blended Learning Platform for Architectural Design Studio Teaching

ERIC Educational Resources Information Center

Steinø, Nicolai; Khalid, Md. Saufuddin

2017-01-01

Much architecture and design teaching is based on the studio format, where the co-presence in time and space of students, instructors and physical learning artefacts form a triangle from which the learning emerges. Yet with the advent of online communication platforms and learning management systems (LMS), there is reason to study how these…

OTLA: A New Model for Online Teaching, Learning and Assessment in Higher Education

ERIC Educational Resources Information Center

Ghilay, Yaron; Ghilay, Ruth

2013-01-01

The study examined a new asynchronous model for online teaching, learning and assessment, called OTLA. It is designed for higher-education institutions and is based on LMS (Learning Management System) as well as other relevant IT tools. The new model includes six digital basic components: text, hypertext, text reading, lectures (voice/video),…

An Application of the Diffusion of Innovations Theory to the Investigation of Blended Language Learning

ERIC Educational Resources Information Center

Grgurovic, Maja

2014-01-01

This study investigates technology-enhanced blended learning in an English as a Second Language (ESL) program from the theoretical perspective of Diffusion of Innovations theory. The study first established that the use of a learning management system (LMS) in two ESL classes represented an educational innovation. Next, the innovation attributes…

Supporting Doctoral Students through the Personalisation of a Graduate Virtual Research Environment

ERIC Educational Resources Information Center

Costello, Robert

2016-01-01

This paper offers a case study in which a traditional Learning Management System (LMS) was enhanced through learning theories and web-based technologies to support the development of doctoral students. The model being used here, can address and support a personalised learning approach to assist postgraduate students, as part of matching their…

Dynamic Fuzzy Logic-Based Quality of Interaction within Blended-Learning: The Rare and Contemporary Dance Cases

ERIC Educational Resources Information Center

Dias, Sofia B.; Diniz, José A.; Hadjileontiadis, Leontios J.

2014-01-01

The combination of the process of pedagogical planning within the Blended (b-) learning environment with the users' quality of interaction ("QoI") with the Learning Management System (LMS) is explored here. The required "QoI" (both for professors and students) is estimated by adopting a fuzzy logic-based modeling approach,…

A Framework for Adopting LMS to Introduce e-Learning in a Traditional Course

ERIC Educational Resources Information Center

Georgouli, Katerina; Skalkidis, Ilias; Guerreiro, Pedro

2008-01-01

As more and more teachers in tertiary education experiment with technology, looking for new ways of enhancing their traditional ways of teaching, the need of flexible tools able to support well planned blended learning scenarios emerges. Learning Management Systems, especially those which are based on open source software, have shown to be very…

Practice and Evaluation of Blended Learning with Cross-Cultural Distance Learning in a Foreign Language Class: Using Mix Methods Data Analysis

ERIC Educational Resources Information Center

Sugie, Satoko; Mitsugi, Makoto

2014-01-01

The Information and Communication Technology (ICT) utilization in Chinese as a "second" foreign language has mainly been focused on Learning Management System (LMS), digital material development, and quantitative analysis of learners' grammatical knowledge. There has been little research that has analyzed the effectiveness of…

The Impact of Frequency on Achievement in Online Courses: A Study from a South Texas University

ERIC Educational Resources Information Center

Kupczynski, Lori; Gibson, Angela M.; Ice, Phil; Richardson, Jennifer; Challoo, Linda

2011-01-01

For over a decade, the learning management system (LMS) has been the primary method of delivering online learning. However, research related instructional design and pedagogical practices within this environment is still in its infancy as compared to face-to-face learning. While several frameworks for understanding pedagogical strategies and…

Learner Autonomy via Asynchronous Online Interactions: A Malaysian Perspective

ERIC Educational Resources Information Center

Kaur, Ranjit; Sidhu, Gurnam Kaur

2010-01-01

The integration of information and communication technologies (ICT) in course offerings in institutions of higher learning (IHLs) is the catalyst towards empowering learners to become autonomous lifelong learners. In an effort to produce quality and independent learners, Learning Management Systems (LMS) are seen as a means to assist educators in…

A Comparison of Two Online Learning Systems

ERIC Educational Resources Information Center

Nichols, Mark

2016-01-01

Open Polytechnic is a single-mode provider of distance education with a rich history of print-based provision. Strategically, the institution is rapidly adopting an online-only approach, with some exceptions for programmes that require student contact. A recent and internal review of Moodle, the Open Polytechnic's learning management system (LMS)…

Exploring Hybrid Instruction in Science: Using LMS for Contextual, Interdisciplinary Active Learning Enrichment

ERIC Educational Resources Information Center

Quarless, Duncan; Nieto, Fernando

2013-01-01

Learning Management Systems are instructional platforms that offer opportunities to address the development of core competencies across disciplines. The emergence of instructional models which place greater emphasis on core skill development in science education help to build interdisciplinary communities through curricular connectivity and…

The Effectiveness of Using Learning Management Systems and Collaborative Tool in Web-Based Teaching of Programming Languages

ERIC Educational Resources Information Center

Cavus, Nadire; Uzunboylu, Huseyin; Ibrahim, Dogan

2006-01-01

This paper is about a pilot study which has been carried out at the Near East University during the 2004/5 Fall Semester using the Moodle LMS [learning management system] together with GREWPtool collaborative editor. The system has been tested with 36 students taking the Java and the Pascal programming courses. The results of the pilot study…

Teacher’s Perception about the Use of E-Learning/Edmodo in Educational Activities

NASA Astrophysics Data System (ADS)

Yanti, H.; Setiawan, A.; Nurhabibah; Yannuar

2018-02-01

This study examined the perception of the teachers about the use of e- learning/Edmodo in their educational activities. The teachers consist of diverse subject. Their perceptions were investigated in terms of three aspects: effects of the use of this technology on their perceived motivation, the perceived usefulness and the perceived ease of use of this technology. Edmodo was set up a Learning Management System (LMS) in an online discussion group of subject. The study was conducted in descriptive method. The data were collected by using a questionnaire, interview, and documentation technique. The findings of the study indicated that the teachers perceived that e-learning/Edmodo is a useful and also easy to use technology. It was found out that the teachers are satisfied with advantages of the use of this new technology in their LMS.

Student Perceptions of the Relationship between Web-Based Instructional Tools and Perceived Attainment of Intended Learning Outcomes

ERIC Educational Resources Information Center

Parenti, Melissa A.

2012-01-01

With the advent of and continual adaptations related to distance learning, there is a recognized need for up to date research in the area of effectiveness of online education programs. More specifically, assessing the capacity to attain academic goals by use of asynchronous and synchronous learning management systems (LMS) that power distance…

The Impact of Using Mobile-Supported Learning Management Systems in Teaching Web Design on the Academic Success of Students and Their Opinions on the Course

ERIC Educational Resources Information Center

Tezer, Murat; Çimsir, Burcu Turan

2018-01-01

This research aimed to examine the impact of using mobile-supported learning management systems (LMS) in teaching web design on the academic success of students and their opinion on the course; and it was conducted on 70 volunteer students (35 experimental, 35 control) enrolled at Giresun University, Technical Sciences Vocational School, Computer…

Rebuilding the LMS for the 21st Century

ERIC Educational Resources Information Center

Demski, Jennifer

2012-01-01

Finally--12 years into the 21st century--higher ed classrooms are turning into incubators for the kind of learning environment that curriculum and instructional technology experts have advocated for years. Yet a key question remains: Can legacy learning management systems (LMSs) be dragged into the 21st century as part of this new educational…

Factors Affecting University Students' Use of Moodle: An Empirical Study Based on TAM

ERIC Educational Resources Information Center

Essel, Daniel Danso; Wilson, Osafo Apeanti

2017-01-01

Higher education institutions are faced with the complex challenges of serving increased enrollment levels within tight budgets. This challenge is prompting many universities to explore new approaches including the use of Learning Management Systems (LMS) such as Moodle for delivering courses to help extend teaching and learning beyond the…

Facebook as an Online Teaching Tool: Effects on Student Participation, Learning, and Overall Course Performance

ERIC Educational Resources Information Center

Camus, Melinda; Hurt, Nicole E.; Larson, Lincoln R.; Prevost, Luanna

2016-01-01

Online discussions are widely viewed as a valuable tool for encouraging student engagement and promoting interaction with course material outside of the traditional classroom. Strategies for conducting online discussions vary and are not confined to traditional, university-sponsored learning management systems (LMS). Social media platforms such as…

Critical Analysis on Open Source LMSs Using FCA

ERIC Educational Resources Information Center

Sumangali, K.; Kumar, Ch. Aswani

2013-01-01

The objective of this paper is to apply Formal Concept Analysis (FCA) to identify the best open source Learning Management System (LMS) for an E-learning environment. FCA is a mathematical framework that represents knowledge derived from a formal context. In constructing the formal context, LMSs are treated as objects and their features as…

Developing Critical L2 Digital Literacy through the Use of Computer-Based Internet-Hosted Learning Management Systems such as Moodle

NASA Astrophysics Data System (ADS)

Meurant, Robert C.

Second Language (L2) Digital Literacy is of emerging importance within English as a Foreign Language (EFL) in Korea, and will evolve to become regarded as the most critical component of overall L2 English Literacy. Computer-based Internet-hosted Learning Management Systems (LMS), such as the popular open-source Moodle, are rapidly being adopted worldwide for distance education, and are also being applied to blended (hybrid) education. In EFL Education, they have a special potential: by setting the LMS to force English to be used exclusively throughout a course website, the meta-language can be made the target L2 language. Of necessity, students develop the ability to use English to navigate the Internet, access and contribute to online resources, and engage in computer-mediated communication. Through such pragmatic engagement with English, students significantly develop their L2 Digital Literacy.

Implementation and evaluation of LMS mobile application: scele mobile based on user-centered design

NASA Astrophysics Data System (ADS)

Banimahendra, R. D.; Santoso, H. B.

2018-03-01

The development of mobile technology is now increasing rapidly, demanding all activities including learning should be done on mobile devices. It shows that the implementation of mobile application as a learning medium needs to be done. This study describes the process of developing and evaluating the Moodle-based mobile Learning Management System (LMS) application called Student Centered e-Learning Environment (SCeLE). This study discusses the process of defining features, implementing features into the application, and evaluating the application. We define the features using user research and literature study, then we implement the application with user-centered design basis, at the last phase we evaluated the application using usability testing and system usability score (SUS). The purpose of this study is to determine the extent to which this application can help the users doing their tasks and provide recommendation for the next research and development.

Factors that Contribute towards Improving Learning Effectiveness Using a Specific Learning Management System (LMS) at the Military Academy (MA): A Demonstration

ERIC Educational Resources Information Center

Pretorius, Andre

2010-01-01

Purpose: The purpose of this paper is to explore the factors that contribute towards learning effectiveness in e-learning courses. A review of previous studies was carried out to determine those factors that are most applicable to a tertiary teaching environment and to propose a model to assess effectiveness in online courses. The virtual learning…

Recommendation System Based On Association Rules For Distributed E-Learning Management Systems

NASA Astrophysics Data System (ADS)

Mihai, Gabroveanu

2015-09-01

Traditional Learning Management Systems are installed on a single server where learning materials and user data are kept. To increase its performance, the Learning Management System can be installed on multiple servers; learning materials and user data could be distributed across these servers obtaining a Distributed Learning Management System. In this paper is proposed the prototype of a recommendation system based on association rules for Distributed Learning Management System. Information from LMS databases is analyzed using distributed data mining algorithms in order to extract the association rules. Then the extracted rules are used as inference rules to provide personalized recommendations. The quality of provided recommendations is improved because the rules used to make the inferences are more accurate, since these rules aggregate knowledge from all e-Learning systems included in Distributed Learning Management System.

Student Perception of Language Achievement and Learner Autonomy in a Blended Korean Language Course: The Case Study of Defense Language Institute Foreign Language Center

ERIC Educational Resources Information Center

Ahn, Misook

2017-01-01

The blended learning model, which combines the traditional face-to-face learning method with an online application such as a learning management system (LMS), became popular and more practical for both teachers and learners in foreign and second language education because of its effective methodology for course delivery and socialization…

Effects of LMS, Self-Efficacy, and Self-Regulated Learning on LMS Effectiveness in Business Education

ERIC Educational Resources Information Center

Eom, Sean B.

2012-01-01

Purpose: The majority of e-learning empirical research studies have focused on the two research streams: outcome comparison studies with classroom-based learning and studies examining potential predictors of e-learning success. The determinants of e-learning success include interactions, instructor support and mentoring, information delivery…

Impact of network aided platforms as educational tools on academic performance and attitude of pharmacology students.

PubMed

Khan, Aftab Ahmed; Siddiqui, Adel Zia; Mohsin, Syed Fareed; Momani, Mohammed Mahmoud Al; Mirza, Eraj Humayun

2017-01-01

This cross-sectional study aimed to examine the impact of learning management system and WhatsApp application as educational tools on students' academic achievement and attitude. The sample population was the students of six medical colleges of Riyadh, Saudi Arabia attending Medical Pharmacology's semester course in Bachelor of Medicine, Bachelor of Surgery (MBBS) program from September 2016 to January 2017. An exploratory approach was adopted based on a comparison between students exposed to only in-class lectures (Group-N), in-class lectures together with WhatsApp platform to disseminate the lecture slides (Group-W) and students group with in-class lectures facility blended with Learning Management System (LMS) and WhatsApp platform (Group-WL). The students' grades were assessed using unified multiple choice questions at the end of the semester. Data were analyzed using descriptive statistics and Pearson correlation (p<0.01). Using learning management system (LMS) and/or WhatsApp messenger tool showed a significant positive correlation in improving students' grades. Additionally, use of WhatsApp enhances students' in-class attendance though statistically insignificant. The results are pivotal for a paradigm shift of in-class lectures and discussion to mobile learning (M-learning). M-learning through WhatsApp may be as an alternative, innovative, and collaborative tool in achieving the required goals in medical education.

Impact of network aided platforms as educational tools on academic performance and attitude of pharmacology students

PubMed Central

Khan, Aftab Ahmed; Siddiqui, Adel Zia; Mohsin, Syed Fareed; Momani, Mohammed Mahmoud Al; Mirza, Eraj Humayun

2017-01-01

Objective: This cross-sectional study aimed to examine the impact of learning management system and WhatsApp application as educational tools on students’ academic achievement and attitude. Methods: The sample population was the students of six medical colleges of Riyadh, Saudi Arabia attending Medical Pharmacology’s semester course in Bachelor of Medicine, Bachelor of Surgery (MBBS) program from September 2016 to January 2017. An exploratory approach was adopted based on a comparison between students exposed to only in-class lectures (Group-N), in-class lectures together with WhatsApp platform to disseminate the lecture slides (Group-W) and students group with in-class lectures facility blended with Learning Management System (LMS) and WhatsApp platform (Group-WL). The students’ grades were assessed using unified multiple choice questions at the end of the semester. Data were analyzed using descriptive statistics and Pearson correlation (p<0.01). Results: Using learning management system (LMS) and/or WhatsApp messenger tool showed a significant positive correlation in improving students’ grades. Additionally, use of WhatsApp enhances students’ in-class attendance though statistically insignificant. Conclusion: The results are pivotal for a paradigm shift of in-class lectures and discussion to mobile learning (M-learning). M-learning through WhatsApp may be as an alternative, innovative, and collaborative tool in achieving the required goals in medical education. PMID:29492081

The Adoption of Technology-Enhanced Instruction to Support Education for All

ERIC Educational Resources Information Center

Khatib, Nahla M.

2014-01-01

This study aimed at investigating the efforts of academic tutors at Arab Open University in Jordan (AOU) to implement technology enhanced instruction through using the learning management system software Moodle (LMS). The AOU has adopted an open learning approach. The aim is to support its vision to reach students in different parts of Jordan and…

Online Learners' Navigational Patterns Based on Data Mining in Terms of Learning Achievement

ERIC Educational Resources Information Center

Keskin, Sinan; Sahin, Muhittin; Ozgur, Adem; Yurdugul, Halil

2016-01-01

The aim of this study is to determine navigational patterns of university students in a learning management system (LMS). It also investigates whether online learners' navigational behaviors differ in terms of their academic achievement (pass, fail). The data for the study comes from 65 third grade students enrolled in online Computer Network and…

Pre-Service Post Graduate Teachers' First Time Experience with Constructivist Learning Environment (CLE) Using MOODLE

ERIC Educational Resources Information Center

Boopathiraj, C.; Chellamani, K.

2015-01-01

The aim of this study is to enlighten and discuss Post Graduate student teachers' first time experiences and their level of satisfaction with the use of Moodle Learning Management System (LMS) during their "Research Methods in Education" course offered online. This study investigated 30 pre-service Post Graduate student teachers' to…

Open Integrated Personal Learning Environment: Towards a New Conception of the ICT-Based Learning Processes

NASA Astrophysics Data System (ADS)

Conde, Miguel Ángel; García-Peñalvo, Francisco José; Casany, Marià José; Alier Forment, Marc

Learning processes are changing related to technological and sociological evolution, taking this in to account, a new learning strategy must be considered. Specifically what is needed is to give an effective step towards the eLearning 2.0 environments consolidation. This must imply the fusion of the advantages of the traditional LMS (Learning Management System) - more formative program control and planning oriented - with the social learning and the flexibility of the web 2.0 educative applications.

Assessing the Success Rate of Students Using a Learning Management System Together with a Collaborative Tool in Web-Based Teaching of Programming Languages

ERIC Educational Resources Information Center

Cavus, Nadire; Ibrahim, Dogan

2007-01-01

The development of collaborative studies in learning has led to a renewed interest in the field of Web-based education. In this experimental study a highly interactive and collaborative virtual teaching environment has been created by supporting Moodle LMS with collaborative learning tool GREWPtool. The aim of this experimental study has been to…

The Use of a Learning Management System (LMS) to Serve as the Virtual Common Space of a Network for the Scholarship of Teaching and Learning (SoTL) in an Academic Department

ERIC Educational Resources Information Center

Bradley, Nicolette; Jadeski, Lorraine; Newton, Genevieve; Ritchie, Kerry; Merrett, Scott; Bettger, William

2013-01-01

Traditionally, undergraduate curriculum committees, consisting of appointed faculty and student representatives, have served as the sole departmental vehicle for investigating, discussing and promoting the scholarship of teaching and learning (SoTL) within an academic department. However, with the universal demand for greater accountability on all…

Facebook Groups as an Academic Teaching Aid: Case Study and Recommendations for Educators

ERIC Educational Resources Information Center

Miron, Eli; Ravid, Gilad

2015-01-01

The move from a walled garden type Learning Management Systems (LMS) to open environments (like Facebook) forces us to adapt new teaching ways. This article offers a brief review of the use of Facebook groups in learning, describes the experience of using Facebook groups in an academic institute, explains the considerations for choosing the type…

Increasing Interactivity in the Online Learning Environment: Using Digital Tools to Support Students in Socially Constructed Meaning-Making

ERIC Educational Resources Information Center

Moreillon, Judi

2015-01-01

As more and more library and LIS education migrates to the online environment, college and university faculty are called upon to expand their pedagogy. Interactivity has been cited as one factor in attracting and retaining students in online courses and programs. LIS educators can reach outside the online learning management system (LMS) to…

The Effect of Badges on the Engagement of Students with Special Educational Needs: A Case Study

ERIC Educational Resources Information Center

Sitra, Ourania; Katsigiannakis, Vangelis; Karagiannidis, Charalampos; Mavropoulou, Sofia

2017-01-01

This paper addresses the perceived benefits from gamification in the context of special education. It presents the findings of a study evaluating the effects of a specific gamification element (badges) on the engagement of five students with special learning needs, through online courses developed on the Moodle Learning Management System (LMS).…

Hook, Line and Canvas: Launching a Professional Development Program to Help Librarians Navigate the Still and Stormy Waters of Online Teaching and Learning

ERIC Educational Resources Information Center

Bliquez, Rebecca; Deeken, Lynn

2016-01-01

Professional development is critically important for librarians trying to establish an embedded presence in online and hybrid courses. The institutional learning management system (LMS) provides a medium for enhanced visibility of both library resources and librarians as instructional collaborators and curriculum designers. This case study…

Factors Affecting Students' Behavioral Intention to Use LMS at a Turkish Post-Secondary Vocational School

ERIC Educational Resources Information Center

Cigdem, Harun; Ozturk, Mustafa

2016-01-01

There is a substantial increase in the use of learning management systems (LMSs) to support teaching and learning activities in higher education institutions. Despite their benefits, student's use them to a limited extend due to a number of factors influencing behaviors. This study executed a three-tier use model to examine the predictors of…

The Effects of Technology on the Community of Inquiry and Satisfaction with Online Courses

ERIC Educational Resources Information Center

Rubin, Beth; Fernandes, Ron; Avgerinou, Maria D.

2013-01-01

This paper extends the research on the Community of Inquiry (CoI) framework of understanding features of successful online learning to include the effects of the software used to support and facilitate it. This study examines how the Learning Management System (LMS) affords people the ability to take actions in an online course. A model is…

Developing Online Course Portal to Improve Teachers’ Competency in Creating Action Research (CAR) Proposal Using Learning Management System (LMS) Moodle

NASA Astrophysics Data System (ADS)

Muhtar, A. A.

2017-02-01

Online course can offer flexible and easy way to improve teachers’ competency in conducting education research, especially in classroom action research (CAR). Teachers can attend the course without physically present in the class. This research aims to (1) develop online course portal to improve teachers’ competency in creating CAR proposal, and (2) produce proper online course portal validated and evaluated from four aspects: learning process, content, graphic user interface and programming. Online course in this research developed using Learning Management System (LMS) Moodle. The research model is using modified Borg & Gall Research and Development (R&D) started from preliminary studies, designing product, creating product, and evaluation. Product validated by three experts from three universities. Research subjects for field test are seven teachers as participants from different schools in several provinces in Indonesia. Based on expert validation and field test results, the product developed in this research categorized as “very good” in all aspects and it is suitable for teacher to improve their competency in creating CAR proposal. Online course portal produced in this research can be used as a proper model for online learning in creating CAR proposal.

LMS in university for in-class education: Synergy of free software, competitive approach and social networks technology

NASA Astrophysics Data System (ADS)

Radygin, V. Y.; Lukyanova, N. V.; Kupriyanov, D. Yu.

2017-01-01

Transformation of learning management systems over last two decades was investigated. The features of using e-learning systems for in-class education were discussed. The necessity of integration e-learning system with the student performance controlling system was shown. The influence of choice of student ranking system on students' motivation was described. The own way to choice of e-learning system design principles and technologies were suggested.

Facilitating job retention for chronically ill employees: perspectives of line managers and human resource managers

PubMed Central

2011-01-01

Background Chronic diseases are a leading contributor to work disability and job loss in Europe. Recent EU policies aim to improve job retention among chronically ill employees. Disability and occupational health researchers argue that this requires a coordinated and pro-active approach at the workplace by occupational health professionals, line managers (LMs) and human resource managers (HRM). Little is known about the perspectives of LMs an HRM on what is needed to facilitate job retention among chronically ill employees. The aim of this qualitative study was to explore and compare the perspectives of Dutch LMs and HRM on this issue. Methods Concept mapping methodology was used to elicit and map statements (ideas) from 10 LMs and 17 HRM about what is needed to ensure continued employment for chronically ill employees. Study participants were recruited through a higher education and an occupational health services organization. Results Participants generated 35 statements. Each group (LMs and HRM) sorted these statements into six thematic clusters. LMs and HRM identified four similar clusters: LMs and HRM must be knowledgeable about the impact of chronic disease on the employee; employees must accept responsibility for work retention; work adaptations must be implemented; and clear company policy. Thematic clusters identified only by LMs were: good manager/employee cooperation and knowledge transfer within the company. Unique clusters identified by HRM were: company culture and organizational support. Conclusions There were both similarities and differences between the views of LMs and HRM on what may facilitate job retention for chronically ill employees. LMs perceived manager/employee cooperation as the most important mechanism for enabling continued employment for these employees. HRM perceived organizational policy and culture as the most important mechanism. The findings provide information about topics that occupational health researchers and planners should address in developing job retention programs for chronically ill workers. PMID:21586139

Facilitating job retention for chronically ill employees: perspectives of line managers and human resource managers.

PubMed

Haafkens, Joke A; Kopnina, Helen; Meerman, Martha G M; van Dijk, Frank J H

2011-05-17

Chronic diseases are a leading contributor to work disability and job loss in Europe. Recent EU policies aim to improve job retention among chronically ill employees. Disability and occupational health researchers argue that this requires a coordinated and pro-active approach at the workplace by occupational health professionals, line managers (LMs) and human resource managers (HRM). Little is known about the perspectives of LMs an HRM on what is needed to facilitate job retention among chronically ill employees. The aim of this qualitative study was to explore and compare the perspectives of Dutch LMs and HRM on this issue. Concept mapping methodology was used to elicit and map statements (ideas) from 10 LMs and 17 HRM about what is needed to ensure continued employment for chronically ill employees. Study participants were recruited through a higher education and an occupational health services organization. Participants generated 35 statements. Each group (LMs and HRM) sorted these statements into six thematic clusters. LMs and HRM identified four similar clusters: LMs and HRM must be knowledgeable about the impact of chronic disease on the employee; employees must accept responsibility for work retention; work adaptations must be implemented; and clear company policy. Thematic clusters identified only by LMs were: good manager/employee cooperation and knowledge transfer within the company. Unique clusters identified by HRM were: company culture and organizational support. There were both similarities and differences between the views of LMs and HRM on what may facilitate job retention for chronically ill employees. LMs perceived manager/employee cooperation as the most important mechanism for enabling continued employment for these employees. HRM perceived organizational policy and culture as the most important mechanism. The findings provide information about topics that occupational health researchers and planners should address in developing job retention programs for chronically ill workers.

Students' Perceptions of the Value of the Elements of an Online Learning Environment: Looking Back in Moving Forward

ERIC Educational Resources Information Center

Palmer, Stuart; Holt, Dale

2010-01-01

In 2003, Deakin University implemented a centralised learning management system (LMS) under the banner of Deakin Studies Online (DSO), as well as implementing policies requiring all its units of study to have at least a basic online presence from 2004. Given the scope of the university's commitment to online education, it was considered essential…

Faculty Views on eTextbooks: A Narrative Study

ERIC Educational Resources Information Center

Bossaller, Jenny; Kammer, Jenna

2014-01-01

eTextbooks are both texts and tools. They provide opportunities for textbook companies to expand their services. Some large textbook companies are offering extensive educational technology products and services along with texts. These etexts, integrated into the Learning Management System (LMS), give instructors opportunities to use integrated…

University Students' Perceptions of Social Networking Sites (SNSs) in Their Educational Experiences at a Regional Australian University

ERIC Educational Resources Information Center

Sadowski, Christina; Pediaditis, Mika; Townsend, Robert

2017-01-01

Higher education institutions, and the way education is delivered and supported, are being transformed by digital technologies. Internationally, institutions are increasingly incorporating online technologies into delivery frameworks and administration -- both through internal learning management systems (LMS) and external social networking sites…

Integrating an Automatic Judge into an Open Source LMS

ERIC Educational Resources Information Center

Georgouli, Katerina; Guerreiro, Pedro

2011-01-01

This paper presents the successful integration of the evaluation engine of Mooshak into the open source learning management system Claroline. Mooshak is an open source online automatic judge that has been used for international and national programming competitions. although it was originally designed for programming competitions, Mooshak has also…

Dentistry students' perceptions of learning management systems.

PubMed

Handal, B; Groenlund, C; Gerzina, T

2010-02-01

This paper reports an exploratory survey study about students' perceptions of learning management systems (LMS) at the Faculty of Dentistry, University of Sydney. Two hundred and fifty-four students enrolled in the Bachelor of Dentistry and the Bachelor of Oral Health programmes participated in an online survey aimed at exploring their beliefs and attitudes as well as their preferences for eLearning tools. Results indicated a strong preference of students for using LMSs as resource repositories rather than for higher-order learning activities such as online discussion forums. This finding holds importance for consideration of the development of the educational resources modalities that support development of essential graduate attributes such as information literacy and collaborative learning.

An Analysis of the Navy Manpower, Personnel, Training and Education Architecture

DTIC Science & Technology

2017-03-01

the courses offered on the Navy 11 Education and Training Command (NETC) Learning Management System (LMS), better known as “E-Learning,” are... Training ,” offers a trimmed down version of the Defense Manpower Course offered at the Naval Postgraduate School (NPS). None fully satisfy training ...Environments (ROC/POE). • “ Training requirements are generated by customer organizations (COCOM’s, Type Commanders, Enterprises, Agencies, and other

Acceptance of Technology and Its Impact on Teachers' Activities in Virtual Classroom: Integrating UTAUT and CoI into a Combined Model

ERIC Educational Resources Information Center

Radovan, Marko; Kristl, Nina

2017-01-01

This study examines the acceptance and use of learning management systems (LMS) among higher-education teachers and the relation between their use of such systems and their teaching approaches in the context of online learning, following the community of inquiry (CoI) framework. A total of 326 teachers at University of Ljubljana completed a…

LMS and New Media

DTIC Science & Technology

2009-08-19

Management of Social Media The Caring Personal Agent SUSAN BULL1, JIM GREER2, GORD MCCALLA2 1 Educational Technology Research Group, Electronic...Discussion Forums, Leader Education , On Demand Learning . 24 Cianciolo, A. (2008) Study Report 2008-05. Program Evaluation for U.S. Army Lifelong...AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Advanced Decision Learning (ADL

Evaluating the Usability and Accessibility of LMS "Blackboard" at King Saud University

ERIC Educational Resources Information Center

Alturki, Uthman T.; Aldraiweesh, Ahmed; Kinshuck

2016-01-01

King Saud University is in the process of adopting and implementing the interactive Blackboard Learning Management Systems (LMSs) with features that allow members of staff and teachers from different faculties to access, upload assignments, send quizzes, download content, and evaluate the academic progress of the members of faculty. However, many…

Design Considerations for Integrating Twitter into an Online Course

ERIC Educational Resources Information Center

Rohr, Linda E.; Costello, Jane; Hawkins, Thomas

2015-01-01

While the use of Twitter for communication and assessment activities in online courses is not new, it has not been without its challenges. This is increasingly true of high enrolment courses. The use of a Twitter Evaluation application which leverages a Learning Management System's (LMS's) application programming interface (API) provides a…

Adoption of the Mobile Campus in a Cyber University

ERIC Educational Resources Information Center

Han, Insook; Han, Seungyeon

2014-01-01

The advantages of mobile technologies have not been lost on higher education institutions, and they have tried to provide educational services through the use of mobile learning management system (LMS). However, offering such services does not necessarily mean that the students will adopt the new technology. Thus, the purpose of this study was to…

Study-MATE: Using Text Messaging to Support Student Transition to University Study

ERIC Educational Resources Information Center

Cahir, Jayde; Huber, Elaine; Handal, Boris; Dutch, Justin; Nixon, Mark

2012-01-01

Students are most likely to drop out of university when first attending. This article analyses the use of technology in supporting the transition process of "first time" university students enrolled in a second-year accounting course. Study-MATE, a study skills program utilising the university's learning management system (LMS)--Blackboard, Google…

Teaching Presence Influencing Online Students' Course Satisfaction at an Institution of Higher Education

ERIC Educational Resources Information Center

Khalid, Mohd N. M.; Quick, Don

2016-01-01

This paper discusses the association between online students' interaction through the Learning Management System (LMS) discussion forum and their reported course satisfaction. The participants in the study reported here were selected from several faculties in one university in Malaysia who were enrolled in at least one hybrid or fully online…

e-Assessment in a Limited-Resources Dental School Using an Open-Source Learning Management System.

PubMed

El Tantawi, Maha M A; Abdelsalam, Maha M; Mourady, Ahmed M; Elrifae, Ismail M B

2015-05-01

e-Assessment provides solutions to some problems encountered in dental students' evaluation. The aim of this study was to evaluate the experience of a limited-resources dental school with e-assessment provided through an open-source learning management system (LMS). Data about users' access and types of e-assessment activities at the Faculty of Dentistry, Alexandria University, Egypt, were obtained from the web-based LMS Moodle. A questionnaire developed to assess students' perceptions of the e-assessment was also sent to students registered in two courses (undergraduate and postgraduate) with the same instructor. The results showed that most e-courses at the school had one form of e-assessment (82%) and, of these, 16.7% had summative assessment activities. There were significant differences among departments in the number of e-courses with e-assessment. One-quarter of e-courses with e-assessment used Moodle quizzes. Of 285 students registered in the two courses that included the questionnaire, 170 responded (response rate=59.6%). The responding students positively perceived the impact of e-assessment on learning and its reliability and security, whereas technical issues and related stresses were negatively perceived. This study suggests that e-assessment can be used at minimal cost in dental schools with limited resources and large class sizes with the least demands on faculty members and teaching staff time. For these schools, an open-source LMS such as Moodle provides formative e-assessment not available otherwise and accommodates various question formats and varying levels of instructors' technical skills. These students seemed to have a positive impression of the e-assessment although technical problems and related stresses are issues that need to be addressed.

Integrating Real-Time Antecedent Rubrics via Blackboard™ into a Community College General Psychology Class

ERIC Educational Resources Information Center

Goomas, David

2015-01-01

Numerous studies have reported on the innovative and effective delivery of online course content by community colleges, but not much has been done on how learning management systems (LMS) can deliver real-time (immediate data delivery) antecedents that inform students of performance requirements. This pilot study used Blackboard's™ interactive…

Hybrid Structures: Faculty Use and Perception of Web-Based Courseware as a Supplement to Face-to-Face Instruction

ERIC Educational Resources Information Center

Woods, Robert; Baker, Jason D.; Hopper, Dave

2004-01-01

The researchers examined responses from 862 faculty members at 38 institutions nationwide using the blackboard Learning Management System (LMS) to supplement their face-to-face instruction. The four research questions addressed the primary uses that faculty make of blackboard, perceptions that faculty have of how certain blackboard features…

Integrating a Digital Concept Mapping into a PPT Slide Writing Project

ERIC Educational Resources Information Center

Yen, Ai Chun; Yang, Pei Yi

2013-01-01

Carried out during a semester-long EFL (English as a foreign language) drama class, this research aimed to scrutinize the effects of digital concept mapping via LMS on English majors' (N = 38) PowerPoint (PPT) slide writing skills in Taiwan. Students were instructed to follow the concept mapping agenda via university learning management system…

Critical Discourse Analysis of Moderated Discussion Board of Virtual University of Pakistan

ERIC Educational Resources Information Center

Perveen, Ayesha

2015-01-01

The paper critically evaluated the discursive practices on the Moderated Discussion Board (MDB) of Virtual University of Pakistan (VUP). The paramount objective of the study was to conduct a critical discourse analysis (CDA) of the MDB on the Learning Management System (LMS) of VUP. For this purpose, the academic power relations of the students…

"LiveUSB Mediated Education": A Method to Facilitate Computer Supported Education

ERIC Educational Resources Information Center

Garrote, Ramon; Pettersson, Tomas; Christie, Michael

2011-01-01

In this paper the authors analyse the design and implementation of a course about learning management systems (LMS). The course was first given in Cuba and then in Guatemala and Peru, within the project USo+I: "Universidad, Sociedad e Innovacion, Mejora de la pertinencia de la educacion en las ingenierias de Latinoamerica" financed by…

Students academic performance based on behavior

NASA Astrophysics Data System (ADS)

Maulida, Juwita Dien; Kariyam

2017-12-01

Utilization of data in an information system that can be used for decision making that utilizes existing data warehouse to help dig useful information to make decisions correctly and accurately. Experience API (xAPI) is one of the enabling technologies for collecting data, so xAPI can be used as a data warehouse that can be used for various needs. One software application whose data is collected in xAPI is LMS. LMS is a software used in an electronic learning process that can handle all aspects of learning, by using LMS can also be known how the learning process and the aspects that can affect learning achievement. One of the aspects that can affect the learning achievement is the background of each student, which is not necessarily the student with a good background is an outstanding student or vice versa. Therefore, an action is needed to anticipate this problem. Prediction of student academic performance using Naive Bayes algorithm obtained accuracy of 67.7983% and error 32.2917%.

Around Marshall

NASA Image and Video Library

1996-06-20

Launched on June 20, 1996, the STS-78 mission’s primary payload was the Life and Microgravity Spacelab (LMS), which was managed by the Marshall Space Flight Center (MSFC). During the 17 day space flight, the crew conducted a diverse slate of experiments divided into a mix of life science and microgravity investigations. In a manner very similar to future International Space Station operations, LMS researchers from the United States and their European counterparts shared resources such as crew time and equipment. Five space agencies (NASA/USA, European Space Agency/Europe (ESA), French Space Agency/France, Canadian Space Agency /Canada, and Italian Space Agency/Italy) along with research scientists from 10 countries worked together on the design, development and construction of the LMS. In this photo, LMS mission scientist Patton Downey and LMS mission manager Mark Boudreaux display the flag that was flown for the mission at MSFC.

The Relationship between Students' Satisfaction in the LMS "Acadox" and Their Perceptions of Its Usefulness, and Ease of Use

ERIC Educational Resources Information Center

Abdel-Maksoud, Nahed F.

2018-01-01

This study examined the relationship between students' satisfaction in the newly developed Learning Management System "Acadox", and their perceptions of its usefulness, and ease of use. The study used a descriptive correlational design to examine the relationships among variables, as they exist in their natural settings. To measure…

Participation in the Virtual Environment of Blended College Courses: An Activity Study of Student Performance

ERIC Educational Resources Information Center

Cavanaugh, Cathy; Mayberry, John; Hargis, Jace

2016-01-01

This paper describes an observational study of the introduction of Sakai's Learning Management System (LMS) into several liberal arts courses at a women's college in the Middle East. Student participation in the CLE was tracked over the course of the semester and summarized by their number of logins and average session length. These measures were…

Participation in the Virtual Environment of Blended College Courses: An Activity Study of Student Performance

ERIC Educational Resources Information Center

Cavanaugh, Cathy; Hargis, Jace; Mayberry, John

2016-01-01

This paper describes a study of success factors in the introductory semester of liberal studies blended courses offered at the bachelor of science level. The influence of student participation in the online course environment was examined, as measured by the number of times students logged into the learning management system (LMS) and average…

A Facilitator's Guide for the Online Course: What Education Leaders Should Know about Virtual Education

ERIC Educational Resources Information Center

Rukobo, Emily Zyko; Penfold, Angela; Adler, C. Ralph; Larson, Heidi; Peterson, Kirsten

2012-01-01

This Facilitator's Guide is based on What Education Leaders Should Know about Virtual Education, an online course designed by the Center on Instruction and the New England Comprehensive Center. The Facilitator's Guide demonstrates step-by-step how to build the course on a learning management system (LMS) and provides instructions on all phases of…

Improvement in American Board of Surgery in-training examination performance with a multidisciplinary surgeon-directed integrated learning platform.

PubMed

Dua, Anahita; Sudan, Ranjan; Desai, Sapan S

2014-01-01

The American Board of Surgery In-Training Examination (ABSITE) is a predictor of resident performance on the general surgery-qualifying examination and plays a role in obtaining competitive fellowships. A learning management system (LMS) permits the delivery of a structured curriculum that appeals to the modern resident owing to the ease of accessibility and all-in-one organization. This study hypothesizes that trainees using a structured surgeon-directed LMS will achieve improved ABSITE scores compared with those using an unstructured approach to the examination. A multidisciplinary print and digital review course with practice questions, review textbooks, weekly reading assignments, and slide and audio reviews integrated within an online LMS was made available to postgraduate year (PGY)-3 and PGY-4 residents in 2008 and 2009. Surveys were emailed requesting ABSITE scores to compare outcomes in those trainees that used the course with those who used an unstructured approach. Statistical analysis was conducted via descriptive statistics and Pearson chi-square with p < 0.05 deemed statistically significant. Surveys were mailed to 508 trainees. There was an 80% (408) response rate. Residents who used structured approaches in both the years achieved the highest scores, followed by those who adopted a structured approach in PGY-4. The residents using an unstructured approach in both the years showed no significant improvement. Residents who used a structured LMS performed significantly better than their counterparts who used an unstructured approach. A properly constructed online education curriculum has the potential to improve ABSITE scores. Copyright © 2014 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

Lightning Mapper Sensor Lens Assembly S.O. 5459: Project Management Plan

NASA Technical Reports Server (NTRS)

Zeidler, Janet

1999-01-01

Kaiser Electro-Optics, Inc. (KEO) has developed this Project Management Plan for the Lightning Mapper Sensor (LMS) program. KEO has integrated a team of experts in a structured program management organization to meet the needs of the LMS program. The project plan discusses KEO's approach to critical program elements including Program Management, Quality Assurance, Configuration Management, and Schedule.

National Wind Distance Learning Collaborative

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dr. James B. Beddow

2013-03-29

Executive Summary The energy development assumptions identified in the Department of Energy's position paper, 20% Wind Energy by 2030, projected an exploding demand for wind energy-related workforce development. These primary assumptions drove a secondary set of assumptions that early stage wind industry workforce development and training paradigms would need to undergo significant change if the workforce needs were to be met. The current training practice and culture within the wind industry is driven by a relatively small number of experts with deep field experience and knowledge. The current training methodology is dominated by face-to-face, classroom based, instructor present training. Givenmore » these assumptions and learning paradigms, the purpose of the National Wind Distance Learning Collaborative was to determine the feasibility of developing online learning strategies and products focused on training wind technicians. The initial project scope centered on (1) identifying resources that would be needed for development of subject matter and course design/delivery strategies for industry-based (non-academic) training, and (2) development of an appropriate Learning Management System (LMS). As the project unfolded, the initial scope was expanded to include development of learning products and the addition of an academic-based training partner. The core partners included two training entities, industry-based Airstreams Renewables and academic-based Lake Area Technical Institute. A third partner, Vision Video Interactive, Inc. provided technology-based learning platforms (hardware and software). The revised scope yielded an expanded set of results beyond the initial expectation. Eight learning modules were developed for the industry-based Electrical Safety course. These modules were subsequently redesigned and repurposed for test application in an academic setting. Software and hardware developments during the project's timeframe enabled redesign providing for student access through the use of tablet devices such as iPads. Early prototype Learning Management Systems (LMS) featuring more student-centric access and interfaces with emerging social media were developed and utilized during the testing applications. The project also produced soft results involving cross learning between and among the partners regarding subject matter expertise, online learning pedagogy, and eLearning technology-based platforms. The partners believe that the most significant, overarching accomplishment of the project was the development and implementation of goals, activities, and outcomes that significantly exceeded those proposed in the initial grant application submitted in 2009. Key specific accomplishments include: (1) development of a set of 8 online learning modules addressing electrical safety as it relates to the work of wind technicians; (3) development of a flexible, open-ended Learning Management System (LMS): (3) creation of a robust body of learning (knowledge, experience, skills, and relationships). Project leaders have concluded that there is substantial resource equity that could be leverage and recommend that it be carried forward to pursue a Next Stage Opportunity relating to development of an online core curriculum for institute and community college energy workforce development programs.« less

A literature review about usability evaluation methods for e-learning platforms.

PubMed

Freire, Luciana Lopes; Arezes, Pedro Miguel; Campos, José Creissac

2012-01-01

The usability analysis of information systems has been the target of several research studies over the past thirty years. These studies have highlighted a great diversity of points of view, including researchers from different scientific areas such as Ergonomics, Computer Science, Design and Education. Within the domain of information ergonomics, the study of tools and methods used for usability evaluation dedicated to E-learning presents evidence that there is a continuous and dynamic evolution of E-learning systems, in many different contexts -academics and corporative. These systems, also known as LMS (Learning Management Systems), can be classified according to their educational goals and their technological features. However, in these systems the usability issues are related with the relationship/interactions between user and system in the user's context. This review is a synthesis of research project about Information Ergonomics and embraces three dimensions, namely the methods, models and frameworks that have been applied to evaluate LMS. The study also includes the main usability criteria and heuristics used. The obtained results show a notorious change in the paradigms of usability, with which it will be possible to discuss about the studies carried out by different researchers that were focused on usability ergonomic principles aimed at E-learning.

Applying Asynchronous Solutions to the Multi-Tasking Realities of a Teacher Education Faculty Unit: Case Study

ERIC Educational Resources Information Center

Moffett, David W.; Claxton, Melba S.; Jordan, Skye L.; Mercer, Patricia P.; Reid, Barbara K.

2007-01-01

The case study describes the early stages of building and using a learning management system (LMS) to aid in the productivity of an education faculty unit. Little to no research exists regarding teacher education units using LMSs to create an online web group for work purposes. The literature review preceding the case study illuminated some of the…

Video Annotation Software Application for Thorough Collaborative Assessment of and Feedback on Microteaching Lessons in Geography Education

ERIC Educational Resources Information Center

van der Westhuizen, Christo P.; Golightly, Aubrey

2015-01-01

This article discusses the process and findings of a study in which video annotation (VideoANT) and a learning management system (LMS) were implemented together in the microteaching lessons of fourth-year geography student teachers. The aim was to ensure adequate assessment of and feedback for each student, since these aspects are, in general, a…

The relationship between student engagement with online content and achievement in a blended learning anatomy course.

PubMed

Green, Rodney A; Whitburn, Laura Y; Zacharias, Anita; Byrne, Graeme; Hughes, Diane L

2017-12-13

Blended learning has become increasingly common in higher education. Recent findings suggest that blended learning achieves better student outcomes than traditional face-to-face teaching in gross anatomy courses. While face-to-face content is perceived as important to learning there is less evidence for the significance of online content in improving student outcomes. Students enrolled in a second-year anatomy course from the physiotherapy (PT), exercise physiology (EP), and exercise science (ES) programs across two campuses were included (n = 500). A structural equation model was used to evaluate the relationship of prior student ability (represented by grade in prerequisite anatomy course) and final course grade and whether the relationship was mediated by program, campus or engagement with the online elements of the learning management system (LMS; proportion of documents and video segments viewed and number of interactions with discussion forums). PT students obtained higher grades and were more likely to engage with online course materials than EP and ES students. Prerequisite grade made a direct contribution to course final grade (P < 0.001) but was also mediated by engagement with LMS videos and discussion forums (P < 0.001). Student learning outcomes in a blended anatomy course can be predicted the by level of engagement with online content. Anat Sci Educ. © 2017 American Association of Anatomists. © 2017 American Association of Anatomists.

Learning algorithms for human-machine interfaces.

PubMed

Danziger, Zachary; Fishbach, Alon; Mussa-Ivaldi, Ferdinando A

2009-05-01

The goal of this study is to create and examine machine learning algorithms that adapt in a controlled and cadenced way to foster a harmonious learning environment between the user and the controlled device. To evaluate these algorithms, we have developed a simple experimental framework. Subjects wear an instrumented data glove that records finger motions. The high-dimensional glove signals remotely control the joint angles of a simulated planar two-link arm on a computer screen, which is used to acquire targets. A machine learning algorithm was applied to adaptively change the transformation between finger motion and the simulated robot arm. This algorithm was either LMS gradient descent or the Moore-Penrose (MP) pseudoinverse transformation. Both algorithms modified the glove-to-joint angle map so as to reduce the endpoint errors measured in past performance. The MP group performed worse than the control group (subjects not exposed to any machine learning), while the LMS group outperformed the control subjects. However, the LMS subjects failed to achieve better generalization than the control subjects, and after extensive training converged to the same level of performance as the control subjects. These results highlight the limitations of coadaptive learning using only endpoint error reduction.

Learning Algorithms for Human–Machine Interfaces

PubMed Central

Fishbach, Alon; Mussa-Ivaldi, Ferdinando A.

2012-01-01

The goal of this study is to create and examine machine learning algorithms that adapt in a controlled and cadenced way to foster a harmonious learning environment between the user and the controlled device. To evaluate these algorithms, we have developed a simple experimental framework. Subjects wear an instrumented data glove that records finger motions. The high-dimensional glove signals remotely control the joint angles of a simulated planar two-link arm on a computer screen, which is used to acquire targets. A machine learning algorithm was applied to adaptively change the transformation between finger motion and the simulated robot arm. This algorithm was either LMS gradient descent or the Moore–Penrose (MP) pseudoinverse transformation. Both algorithms modified the glove-to-joint angle map so as to reduce the endpoint errors measured in past performance. The MP group performed worse than the control group (subjects not exposed to any machine learning), while the LMS group outperformed the control subjects. However, the LMS subjects failed to achieve better generalization than the control subjects, and after extensive training converged to the same level of performance as the control subjects. These results highlight the limitations of coadaptive learning using only endpoint error reduction. PMID:19203886

Stufenweise Integration von eLearning an der Technischen Universität München

NASA Astrophysics Data System (ADS)

Pätzold, Sebastian; Graf, Stephan; Gergintchev, Ivan; Pongratz, Hans; Rathmayer, Sabine

Der vorliegende Beitrag beschreibt als Best Practice Beispiel die stufenweise Integration eines Learning Management Systems (LMS) in die Infrastruktur von Information und Kommunikation (IuK) der Technischen Universität München (TUM). Dabei wird sowohl die Konsolidierung mehrfach angebotener Funktionalitäten und Dienste in den verschiedenen Portalen der Universität als auch die sukzessive Optimierung der Abläufe aufgezeigt. Gleichzeitig wird auf zukünftige weitere Entwicklungen hin zu einer vollständigen Integration der IuK, aber auch auf die Probleme in den unterschiedlichen Stadien der Entwicklung eingegangen.

The Process of Becoming an Embedded Curriculum Librarian in Multiple Health Sciences Programs.

PubMed

Wilson, Gwen

2015-01-01

Higher education is moving to offer more fully online programs, and the health science fields are no different. These programs are either hybrid or completely online. It is up to the health sciences librarian to adapt services offered by the academic library to these types of courses. This column discusses the multiple ways a librarian can be an embedded librarian in a course using a learning management system (LMS). The process of creating a customized embedded librarian program, results, and lessons learned from the different embedded librarian roles are also discussed.

Charles Brady in Life and Microgravity Spacelab (LMS) Onboard STS-78

NASA Technical Reports Server (NTRS)

1996-01-01

Launched on June 20, 1996, the STS-78 mission's primary payload was the Life and Microgravity Spacelab (LMS), which was managed by the Marshall Space Flight Center (MSFC). During the 17 day space flight, the crew conducted a diverse slate of experiments divided into a mix of life science and microgravity investigations. In a manner very similar to future International Space Station operations, LMS researchers from the United States and their European counterparts shared resources such as crew time and equipment. Five space agencies (NASA/USA, European Space Agency/Europe (ESA), French Space Agency/France, Canadian Space Agency /Canada, and Italian Space Agency/Italy) along with research scientists from 10 countries worked together on the design, development and construction of the LMS. In this onboard photograph, mission specialist Charles Brady is working in the LMS.

Teaching using moodle in mathematics education

NASA Astrophysics Data System (ADS)

Handayanto, A.; Supandi, S.; Ariyanto, L.

2018-05-01

The aim of this study is to determine the effect of Learning Modeling System (LMS) Moodle in learning. The population is taken from all students of Mathematics Education, University of PGRI Semarang. The sample was randomly selected from five different course groups. The initial score is taken from the semester test, and the final score is taken through the semester test after the five groups are taught using Moodle. The results of both test results are compared to find out the increase in learning outcomes. Meanwhile, the student's attitude toward learning is taken through his mathematical disposition through questionnaire. The results show that there was a significant increase in exam results on the final exam of the semester. This result is supported by student learning interest which increases on average after using LMS Moodle taken from disposition data.

Participation in asynchronous online discussion forums does improve student learning of gross anatomy.

PubMed

Green, Rodney A; Farchione, Davide; Hughes, Diane L; Chan, Siew-Pang

2014-01-01

Asynchronous online discussion forums are common in blended learning models and are popular with students. A previous report has suggested that participation in these forums may assist student learning in a gross anatomy subject but it was unclear as to whether more academically able students post more often or whether participation led to improved learning outcomes. This study used a path model to analyze the contribution of forum participation, previous academic ability, and student campus of enrolment to final marks in a multicampus gross anatomy course for physiotherapy students. The course has a substantial online learning management system (LMS) that incorporates asynchronous forums as a learning tool, particularly to answer learning objectives. Students were encouraged to post new threads and answer queries in threads started by others. The forums were moderated weekly by staff. Discussion forums were the most used feature of the LMS site with 31,920 hits. Forty-eight percent of the students posted at least once with 186 threads initiated by students and a total of 608 posts. The total number of posts made a significant direct contribution to final mark (P = 0.008) as did previous academic ability (P = 0.002). Although campus did not contribute to final mark, there was a trend for students at the campus where the course coordinator was situated to post more often than those at the other campus (P = 0.073). These results indicate that asynchronous online discussion forums can be an effective tool for improving student learning outcomes as evidenced by final marks in gross anatomy teaching. Copyright © 2013 American Association of Anatomists.

Atypical Uterine Smooth Muscle Tumors: A Retrospective Evaluation of Clinical and Pathologic Features.

PubMed

Maltese, Giuseppa; Fontanella, Caterina; Lepori, Stefano; Scaffa, Cono; Fucà, Giovanni; Bogani, Giorgio; Provenzano, Salvatore; Carcangiu, Maria Luisa; Raspagliesi, Francesco; Lorusso, Domenica

2018-01-01

Clinical characteristics combined with new biomarkers help discriminate between atypical uterine smooth muscle tumors (AUSMT) and leiomyosarcomas (LMS). We retrospectively collected a series of leiomyomas (LM), AUSMT, and LMS. Estrogen receptors (ER), progesterone receptors (PR), p16, Ki-67, and p53 expression were assessed by immunohistochemistry. For AUSMT patients, immunohistochemistry evaluations were performed at the time of diagnosis and at recurrences. A total of 27 cases of AUSMT, 22 LM, and 31 LMS were identified. The expression of ER and PR decreased from LM to LMS (ER+: LM 95.5%, AUSMT 88.9%, LMS 41.9%, p < 0.001; PR+: LM 100%, AUSMT 88.9%, LMS 38.2%, p = 0.002). By contrast, p16 and p53 expression increased (p16+: LM 4.5%, AUSMT 40.7%, LMS 45.2%, p = 0.004; p53: LM 9.1%, AUSMT 33.3%, LMS 58.1%, p = 0.001). At a median follow-up of 33.47 months, 40.7% of patients with AUSMT experienced recurrent disease, 6 patients relapsed as AUSMT and 5 as LMS. In univariate analysis was observed that ER status (p = 0.027) and p53 expression (p = 0.015) predicted risk of relapse. Treatment of AUSMT should be centralized in dedicated centers. International collaborations are needed to optimize research strategy, which may lead to the identification of new useful biomarkers and to improvement in the clinical management of this rare disease. © 2017 S. Karger AG, Basel.

Medaka Fish Embryo Developed for STS-78 Life and Microgravity Spacelab (LMS)

NASA Technical Reports Server (NTRS)

1996-01-01

Launched on June 20, 1996, the STS-78 mission's primary payload was the Life and Microgravity Spacelab (LMS), which was managed by the Marshall Space Flight Center (MSFC). During the 17 day space flight, the crew conducted a diverse slate of experiments divided into a mix of life science and microgravity investigations. In a manner very similar to future International Space Station operations, LMS researchers from the United States and their European counterparts shared resources such as crew time and equipment. Five space agencies (NASA/USA, European Space Agency/Europe (ESA), French Space Agency/France, Canadian Space Agency /Canada, and Italian Space Agency/Italy) along with research scientists from 10 countries worked together on the design, development and construction of the LMS. This photo represents the development of Medaka Fish Embryos, one of the many studies of the LMS mission.

Adaptive Inverse Control for Rotorcraft Vibration Reduction

NASA Technical Reports Server (NTRS)

Jacklin, Stephen A.

1985-01-01

This thesis extends the Least Mean Square (LMS) algorithm to solve the mult!ple-input, multiple-output problem of alleviating N/Rev (revolutions per minute by number of blades) helicopter fuselage vibration by means of adaptive inverse control. A frequency domain locally linear model is used to represent the transfer matrix relating the higher harmonic pitch control inputs to the harmonic vibration outputs to be controlled. By using the inverse matrix as the controller gain matrix, an adaptive inverse regulator is formed to alleviate the N/Rev vibration. The stability and rate of convergence properties of the extended LMS algorithm are discussed. It is shown that the stability ranges for the elements of the stability gain matrix are directly related to the eigenvalues of the vibration signal information matrix for the learning phase, but not for the control phase. The overall conclusion is that the LMS adaptive inverse control method can form a robust vibration control system, but will require some tuning of the input sensor gains, the stability gain matrix, and the amount of control relaxation to be used. The learning curve of the controller during the learning phase is shown to be quantitatively close to that predicted by averaging the learning curves of the normal modes. For higher order transfer matrices, a rough estimate of the inverse is needed to start the algorithm efficiently. The simulation results indicate that the factor which most influences LMS adaptive inverse control is the product of the control relaxation and the the stability gain matrix. A small stability gain matrix makes the controller less sensitive to relaxation selection, and permits faster and more stable vibration reduction, than by choosing the stability gain matrix large and the control relaxation term small. It is shown that the best selections of the stability gain matrix elements and the amount of control relaxation is basically a compromise between slow, stable convergence and fast convergence with increased possibility of unstable identification. In the simulation studies, the LMS adaptive inverse control algorithm is shown to be capable of adapting the inverse (controller) matrix to track changes in the flight conditions. The algorithm converges quickly for moderate disturbances, while taking longer for larger disturbances. Perfect knowledge of the inverse matrix is not required for good control of the N/Rev vibration. However it is shown that measurement noise will prevent the LMS adaptive inverse control technique from controlling the vibration, unless the signal averaging method presented is incorporated into the algorithm.

Data Management Coordinators Monitor STS-78 Mission at the Huntsville Operations Support Center

NASA Technical Reports Server (NTRS)

1996-01-01

Launched on June 20, 1996, the STS-78 mission's primary payload was the Life and Microgravity Spacelab (LMS), which was managed by the Marshall Space Flight Center (MSFC). During the 17 day space flight, the crew conducted a diverse slate of experiments divided into a mix of life science and microgravity investigations. In a manner very similar to future International Space Station operations, LMS researchers from the United States and their European counterparts shared resources such as crew time and equipment. Five space agencies (NASA/USA, European Space Agency/Europe (ESA), French Space Agency/France, Canadian Space Agency /Canada, and Italian Space Agency/Italy) along with research scientists from 10 countries worked together on the design, development and construction of the LMS. This photo represents Data Management Coordinators monitoring the progress of the mission at the Huntsville Operations Support Center (HOSC) Spacelab Payload Operations Control Center (SL POCC) at MSFC. Pictured are assistant mission scientist Dr. Dalle Kornfeld, Rick McConnel, and Ann Bathew.

Competition-Based Learning: A Model for the Integration of Competitions with Project-Based Learning Using Open Source LMS

ERIC Educational Resources Information Center

Issa, Ghassan; Hussain, Shakir M.; Al-Bahadili, Hussein

2014-01-01

In an effort to enhance the learning process in higher education, a new model for Competition-Based Learning (CBL) is presented. The new model utilizes two well-known learning models, namely, the Project-Based Learning (PBL) and competitions. The new model is also applied in a networked environment with emphasis on collective learning as well as…

Automating Individualized Formative Feedback in Large Classes Based on a Directed Concept Graph

PubMed Central

Schaffer, Henry E.; Young, Karen R.; Ligon, Emily W.; Chapman, Diane D.

2017-01-01

Student learning outcomes within courses form the basis for course completion and time-to-graduation statistics, which are of great importance in education, particularly higher education. Budget pressures have led to large classes in which student-to-instructor interaction is very limited. Most of the current efforts to improve student progress in large classes, such as “learning analytics,” (LA) focus on the aspects of student behavior that are found in the logs of Learning Management Systems (LMS), for example, frequency of signing in, time spent on each page, and grades. These are important, but are distant from providing help to the student making insufficient progress in a course. We describe a computer analytical methodology which includes a dissection of the concepts in the course, expressed as a directed graph, that are applied to test questions, and uses performance on these questions to provide formative feedback to each student in any course format: face-to-face, blended, flipped, or online. Each student receives individualized assistance in a scalable and affordable manner. It works with any class delivery technology, textbook, and learning management system. PMID:28293202

Spacelab

NASA Image and Video Library

1996-05-05

Launched on June 20, 1996, the STS-78 mission’s primary payload was the Life and Microgravity Spacelab (LMS), which was managed by the Marshall Space Flight Center (MSFC). During the 17 day space flight, the crew conducted a diverse slate of experiments divided into a mix of life science and microgravity investigations. In a manner very similar to future International Space Station operations, LMS researchers from the United States and their European counterparts shared resources such as crew time and equipment. Five space agencies (NASA/USA, European Space Agency/Europe (ESA), French Space Agency/France, Canadian Space Agency /Canada, and Italian Space Agency/Italy) along with research scientists from 10 countries worked together on the design, development and construction of the LMS. This photo represents Data Management Coordinators monitoring the progress of the mission at the Huntsville Operations Support Center (HOSC) Spacelab Payload Operations Control Center (SL POCC) at MSFC. Pictured are assistant mission scientist Dr. Dalle Kornfeld, Rick McConnel, and Ann Bathew.

LMS Projects: A Platform for Intergenerational E-Learning Collaboration

ERIC Educational Resources Information Center

Lyashenko, Maria Sergeyevna; Frolova, Natalja Hidarovna

2014-01-01

Intergenerational learning (IGL) is the process of bringing seniors and juniors together in a collaborative space. Universities have been known to create a stimulating context for generations to share and acquire skills. The purpose of this paper is to present the results of research in the field of intergenerational learning and skills sharing.…

Technology Enhanced Learning: Virtual Realities; Concrete Results--Case Study on the Impact of TEL on Learning

ERIC Educational Resources Information Center

Al-Khatib, Hayat

2011-01-01

Technology Enhanced Learning is a feature of 21st century education. Innovations in ICT have provided unbound access to information in support of the learning process (APTEL, 2010; Allert et al, 2002; Baldry et al, 2006; Frustenberg et al, 2001; Sarkis, 2010). LMS has been extensively put to use in universities and educational institutions to…

The Four Scaffolding Modules for Collaborative Problem-Based Learning through the Computer Network on Moodle LMS for the Computer Programming Course

ERIC Educational Resources Information Center

Tiantong, Monchai; Teemuangsai, Sanit

2013-01-01

Scaffolding is a learning approach designed to promote a deeper understanding, it is the support given during the learning process which is tailored to the needs of the student with the intention of helping the student achieve the learning goals, including resources, a compelling task, templates and guides, and guidance on the development of…

Semantic Web-Driven LMS Architecture towards a Holistic Learning Process Model Focused on Personalization

ERIC Educational Resources Information Center

Kerkiri, Tania

2010-01-01

A comprehensive presentation is here made on the modular architecture of an e-learning platform with a distinctive emphasis on content personalization, combining advantages from semantic web technology, collaborative filtering and recommendation systems. Modules of this architecture handle information about both the domain-specific didactic…

Long distance education for croatian nurses with open source software.

PubMed

Radenovic, Aleksandar; Kalauz, Sonja

2006-01-01

Croatian Nursing Informatics Association (CNIA) has been established as result of continuing work on promoting nursing informatics in Croatia. Main goals of CNIA are promoting nursing informatics and education of nurses about nursing informatics and using information technology in nursing process. CNIA in start of work is developed three courses from nursing informatics all designed with support of long distance education with open source software. Courses are: A - 'From Data to Wisdom', B - 'Introduction to Nursing Informatics' and C - 'Nursing Informatics I'. Courses A and B are obligatory for C course. Technology used to implement these online courses is based on the open source Learning Management System (LMS), Claroline, free online collaborative learning platform. Courses are divided in two modules/days. First module/day participants have classical approach to education and second day with E-learning from home. These courses represent first courses from nursing informatics' and first long distance education for nurses also.

Identifying Information Behavior in Information Search and Retrieval through Learning Activities Using an E-learning Platform Case: Interamerican School of Library and Information Science at the University of Antioquia (Medellin-Colombia)

ERIC Educational Resources Information Center

Tirado, Alejandro Uribe; Munoz, Wilson Castano

2011-01-01

This text presents the future of librarian education as exemplified by the Interamerican School of Library and Information Science at the University of Antioquia (Medellin-Colombia), using an online learning platform-LMS (Moodle) and through different personalized and collaborative learning activities and tools that help students identify their…

Web-Based Learning Support System

NASA Astrophysics Data System (ADS)

Fan, Lisa

Web-based learning support system offers many benefits over traditional learning environments and has become very popular. The Web is a powerful environment for distributing information and delivering knowledge to an increasingly wide and diverse audience. Typical Web-based learning environments, such as Web-CT, Blackboard, include course content delivery tools, quiz modules, grade reporting systems, assignment submission components, etc. They are powerful integrated learning management systems (LMS) that support a number of activities performed by teachers and students during the learning process [1]. However, students who study a course on the Internet tend to be more heterogeneously distributed than those found in a traditional classroom situation. In order to achieve optimal efficiency in a learning process, an individual learner needs his or her own personalized assistance. For a web-based open and dynamic learning environment, personalized support for learners becomes more important. This chapter demonstrates how to realize personalized learning support in dynamic and heterogeneous learning environments by utilizing Adaptive Web technologies. It focuses on course personalization in terms of contents and teaching materials that is according to each student's needs and capabilities. An example of using Rough Set to analyze student personal information to assist students with effective learning and predict student performance is presented.

Adaptive filtering with the self-organizing map: a performance comparison.

PubMed

Barreto, Guilherme A; Souza, Luís Gustavo M

2006-01-01

In this paper we provide an in-depth evaluation of the SOM as a feasible tool for nonlinear adaptive filtering. A comprehensive survey of existing SOM-based and related architectures for learning input-output mappings is carried out and the application of these architectures to nonlinear adaptive filtering is formulated. Then, we introduce two simple procedures for building RBF-based nonlinear filters using the Vector-Quantized Temporal Associative Memory (VQTAM), a recently proposed method for learning dynamical input-output mappings using the SOM. The aforementioned SOM-based adaptive filters are compared with standard FIR/LMS and FIR/LMS-Newton linear transversal filters, as well as with powerful MLP-based filters in nonlinear channel equalization and inverse modeling tasks. The obtained results in both tasks indicate that SOM-based filters can consistently outperform powerful MLP-based ones.

Integrating an Educational Game in Moodle LMS

ERIC Educational Resources Information Center

Minovic, Miroslav; Milovanovic, Milos; Minovic, Jelena; Starcevic, Dusan

2012-01-01

The authors present a learning platform based on a computer game. Learning games combine two industries: education and entertainment, which is often called "Edutainment." The game is realized as a strategic game (similar to Risk[TM]), implemented as a module for Moodle CMS, utilizing Java Applet technology. Moodle is an open-source course…

How Do B-Learning and Learning Patterns Influence Learning Outcomes?

PubMed Central

Sáiz Manzanares, María Consuelo; Marticorena Sánchez, Raúl; García Osorio, César Ignacio; Díez-Pastor, José F.

2017-01-01

Learning Management System (LMS) platforms provide a wealth of information on the learning patterns of students. Learning Analytics (LA) techniques permit the analysis of the logs or records of the activities of both students and teachers on the on-line platform. The learning patterns differ depending on the type of Blended Learning (B-Learning). In this study, we analyse: (1) whether significant differences exist between the learning outcomes of students and their learning patterns on the platform, depending on the type of B-Learning [Replacement blend (RB) vs. Supplemental blend (SB)]; (2) whether a relation exists between the metacognitive and the motivational strategies (MS) of students, their learning outcomes and their learning patterns on the platform. The 87,065 log records of 129 students (69 in RB and 60 in SB) in the Moodle 3.1 platform were analyzed. The results revealed different learning patterns between students depending on the type of B-Learning (RB vs. SB). We have found that the degree of blend, RB vs. SB, seems to condition student behavior on the platform. Learning patterns in RB environments can predict student learning outcomes. Additionally, in RB environments there is a relationship between the learning patterns and the metacognitive and (MS) of the students. PMID:28559866

How Do B-Learning and Learning Patterns Influence Learning Outcomes?

PubMed

Sáiz Manzanares, María Consuelo; Marticorena Sánchez, Raúl; García Osorio, César Ignacio; Díez-Pastor, José F

2017-01-01

Learning Management System (LMS) platforms provide a wealth of information on the learning patterns of students. Learning Analytics (LA) techniques permit the analysis of the logs or records of the activities of both students and teachers on the on-line platform. The learning patterns differ depending on the type of Blended Learning (B-Learning). In this study, we analyse: (1) whether significant differences exist between the learning outcomes of students and their learning patterns on the platform, depending on the type of B-Learning [Replacement blend (RB) vs. Supplemental blend (SB)]; (2) whether a relation exists between the metacognitive and the motivational strategies (MS) of students, their learning outcomes and their learning patterns on the platform. The 87,065 log records of 129 students (69 in RB and 60 in SB) in the Moodle 3.1 platform were analyzed. The results revealed different learning patterns between students depending on the type of B-Learning (RB vs. SB). We have found that the degree of blend, RB vs. SB, seems to condition student behavior on the platform. Learning patterns in RB environments can predict student learning outcomes. Additionally, in RB environments there is a relationship between the learning patterns and the metacognitive and (MS) of the students.

Feasibility of laser marking in Barrett's esophagus with volumetric laser endomicroscopy: first-in-man pilot study.

PubMed

Swager, Anne-Fré; de Groof, Albert J; Meijer, Sybren L; Weusten, Bas L; Curvers, Wouter L; Bergman, Jacques J

2017-09-01

Volumetric laser endomicroscopy (VLE) provides a circumferential scan of the esophageal wall layers and has potential to improve detection of neoplasia in Barrett's esophagus (BE). The novel VLE laser marking system enables direct in vivo marking of suspicious areas as identified on VLE. These laser marked areas can subsequently be targeted for biopsies. The aim was to evaluate the visibility and positional accuracy of laser marks (LMs) in different esophageal tissue types on white light endoscopy (WLE) and VLE. Patients with BE with or without neoplasia underwent imaging with VLE. Protocol refinements were practiced in a learning phase. In the second phase, visibility of LMs was assessed by random marking in squamous, BE, and gastric tissue. In phase 3, positional accuracy of the LMs was tested by identifying and laser marking surrogate targets (endoscopically placed cautery marks). In the final phase, the most suspicious areas for neoplasia were identified in each patient using VLE, targeted by LMs, and biopsy samples subsequently obtained. Sixteen patients with BE were included (14 men; median age, 68 years), 1 of whom was included twice in different study phases. Worst histologic diagnoses were 9 non-dysplastic Barrett's esophagus (NDBE), 3 low-grade dysplasia (LGD), 4 high-grade dysplasia (HGD), and 1 early adenocarcinoma (EAC). In total, 222 LMs were placed, of which 97% was visible on WLE. All LMs were visible on VLE directly after marking, and 86% could be confirmed during post hoc analysis. LM targeting was successful with positional accuracy in 85% of cautery marks. Inaccurate targeting was caused by system errors or difficult cautery mark visualization on VLE. In the final phase (5 patients), 18 areas suspicious on VLE were identified, which were all successfully targeted by LMs (3 EAC, 3 HGD, 1 LGD, and 11 NDBE). Mean VLE procedure time was 22 minutes (±6 minutes standard deviation); mean endoscopy time was 56 minutes (±17 minutes). No adverse events were reported. This first-in-human study of VLE-guided laser marking was found to be feasible and safe in 17 procedures. Most LMs were visible on WLE and VLE. Targeting VLE areas of interest proved to be highly successful. VLE-guided laser marking may improve the detection and delineation of Barrett's neoplasia in the future. Copyright © 2017 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

Using Mobile Apps and Social Media for Online Learner-Generated Content

ERIC Educational Resources Information Center

Henry, Paul David

2014-01-01

As part of an evolutionary approach to extending and enhancing the online learning experience for adult students in the LMS-based online college courses that I teach, I have been introducing learning activities that use social media and mobile devices. However, realizing that student adoption of mobile devices with data plans such as smartphones…

Current Capabilities, Issues, and Trends in LMSs and Authoring Tools

DTIC Science & Technology

2009-08-18

architecture  Embedded best-practice design principles  Support for immersive learning technologies  Support for social media 8 LMSs LMS Functionality is... Learning System Multimedia content Application demos VOIP Real-time Collaboration technologies from Adobe Connect Pro, WebEx, LiveMeeting, & Centra...ORGANIZATION NAME(S) AND ADDRESS(ES) Advanced Decision Learning (ADL),ADL Co-Lab,1901 N. Beauregard Street Suite 600,Alexandria,VA,22311 8

Course transformation: Content, structure and effectiveness analysis

NASA Astrophysics Data System (ADS)

DuHadway, Linda P.

The organization of learning materials is often limited by the systems available for delivery of such material. Currently, the learning management system (LMS) is widely used to distribute course materials. These systems deliver the material in a text-based, linear way. As online education continues to expand and educators seek to increase their effectiveness by adding more effective active learning strategies, these delivery methods become a limitation. This work demonstrates the possibility of presenting course materials in a graphical way that expresses important relations and provides support for manipulating the order of those materials. The ENABLE system gathers data from an existing course, uses text analysis techniques, graph theory, graph transformation, and a user interface to create and present graphical course maps. These course maps are able to express information not currently available in the LMS. Student agents have been developed to traverse these course maps to identify the variety of possible paths through the material. The temporal relations imposed by the current course delivery methods have been replaced by prerequisite relations that express ordering that provides educational value. Reducing the connections to these more meaningful relations allows more possibilities for change. Technical methods are used to explore and calibrate linear and nonlinear models of learning. These methods are used to track mastery of learning material and identify relative difficulty values. Several probability models are developed and used to demonstrate that data from existing, temporally based courses can be used to make predictions about student success in courses using the same material but organized without the temporal limitations. Combined, these demonstrate the possibility of tools and techniques that can support the implementation of a graphical course map that allows varied paths and provides an enriched, more informative interface between the educator, the student, and the learning material. This fundamental change in how course materials are presented and interfaced with has the potential to make educational opportunities available to a broader spectrum of people with diverse abilities and circumstances. The graphical course map can be pivotal in attaining this transition.

Gender Difference in Academic Planning Activity among Medical Students

PubMed Central

Nguyen, Huy Van; Giang, Thao Thach

2013-01-01

Background In Vietnam, as doctor of medicine is socially considered a special career, both men and women who are enrolled in medical universities often study topics of medicine seriously. However, as culturally expected, women often perform better than men. Because of this, teaching leadership and management skill (LMS) to develop academic planning activity (APA) for female medical students would also be expected to be more effective than male counterparts. This research aimed to compare by gender the effect of teaching LMS on increasing APA, using propensity score matching (PSM). Methods In a cross-sectional survey utilizing a self-reported structured questionnaire on a systematic random sample of 421 male and female medical students in Hanoi Medical University, this study adopted first regression techniques to construct a fit model, then PSM to create a matched control group in order to allow for evaluating the effect of LMS education. Results There were several interesting gender differences. First, while for females LMS education had both direct and indirect effects on APA, it had only direct effect on males’ APA. Second, after PSM to adjust for the possible confounders to balance statistically two groups – with and without LMS education, there is statistically a significant difference in APA between male and female students, making a net difference of 11% (p<.01), equivalent to 173 students. The difference in APA between exposed and matched control group in males and females was 9% and 20%, respectively. These estimates of 9.0 and 20.0 percentage point increase can be translated into the practice of APA by 142 males and 315 females, respectively, in the population. These numbers of APA among male and female students can be explained by LMS education. Conclusions Gender appears to be a factor explaining in part academic planning activity. PMID:23418467

Using blended learning and out-of-school visits: pedagogies for effective science teaching in the twenty-first century

NASA Astrophysics Data System (ADS)

Coll, Sandhya Devi; Coll, Richard Kevin

2018-04-01

Background: Recent research and curriculum reforms have indicated the need for diversifying teaching approaches by drawing upon student interest and engagement in ways which makes learning science meaningful. Purpose: This study examines the integration of informal/free choice learning which occurred during learning experiences outside school (LEOS) with classroom learning using digital technologies. Specifically, the digital technologies comprised a learning management system (LMS), Moodle, which fits well with students' lived experiences and their digital world. Design and Method: This study examines three out-of-school visits to Informal Science Institutes (ISI) using a digitally integrated fieldtrip inventory (DIFI) Model. Research questions were analysed using thematic approach emerging along with semi-structured interviews, before, during and after the visit, and assessing students' learning experiences. Data comprised photographs, field notes, and unobtrusive observations of the classroom, wiki postings, student work books and teacher planning diaries. Results: We argue, that pre- and post-visit planning using the DIFI Model is more likely to engage learners, and the use of a digital learning platform was even more likely to encourage collaborative learning. The conclusion can also be drawn that students' level of motivation for collaborative learning positively correlates with their improvement in academic achievement.

Creating Collaborative and Convenient Learning Environment Using Cloud-Based Moodle LMS: An Instructor and Administrator Perspective

ERIC Educational Resources Information Center

Kumar, Vikas; Sharma, Deepika

2016-01-01

Students in the digital era are habitual of using digital devices not only for playing and interacting with their friends and peers, but also as a tool for education and learning. These digital natives are highly obsessed with the internet driven portable devices and always demand for a multimedia rich content. This specific demand needs to be…

Meeting the Challenge of Instructor Shortages: A Blended Teaching and Learning Model for a Neuroscience Course in a Doctor of Physical Therapy Program.

PubMed

Ge, Weiqing

2018-01-01

Physical therapy workforce shortages are expected to increase for all 50 states through 2030. There is a recognized nationwide unprecedented shortage of well-prepared physical therapy instructors. One practical solution can be to share instructors among Doctor of Physical Therapy (DPT) programs using a blended teaching and learning model. The purpose of this project was to evaluate the effectiveness of a blended teaching and learning model for a neuroscience course in a DPT program. Faculty members from two DPT programs collaborated to develop, implement, and evaluate a blended teaching and learning model. The Blackboard Learning Management System (LMS) was available at both institutions and chosen as the learning platform. The design of this research study was retrospective nonexperimental observational. The overall feedback from the students was positive. Most students (91.6%) strongly agreed or agreed that the content of the course was appropriate for learning neuroscience. The students taking this blended course performed slightly better than the students taking the traditional course, though there was no significant difference (p=0.06). The results support the use of a blended teaching and learning model to meet faculty shortage challenges. Future research with a larger sample size is necessary.

Effects of locomotor skill program on minority preschoolers' physical activity levels.

PubMed

Alhassan, Sofiya; Nwaokelemeh, Ogechi; Ghazarian, Manneh; Roberts, Jasmin; Mendoza, Albert; Shitole, Sanyog

2012-08-01

This pilot study examined the effects of a teacher-taught, locomotor skill (LMS)-based physical activity (PA) program on the LMS and PA levels of minority preschooler-aged children. Eight low-socioeconomic status preschool classrooms were randomized into LMS-PA (LMS-oriented lesson plans) or control group (supervised free playtime). Interventions were delivered for 30 min/day, five days/week for six months. Changes in PA (accelerometer) and LMS variables were assessed with MANCOVA. LMS-PA group exhibited a significant reduction in during-preschool (F (1,16) = 6.34, p = .02, d = 0.02) and total daily (F (1,16) = 9.78, p = .01, d = 0.30) percent time spent in sedentary activity. LMS-PA group also exhibited significant improvement in leaping skills, F (1, 51) = 7.18, p = .01, d = 0.80). No other, significant changes were observed. The implementation of a teacher-taught, LMS-based PA program could potentially improve LMS and reduce sedentary time of minority preschoolers.

Creation and Assessment of an Active e-Learning Introductory Geology Course

NASA Astrophysics Data System (ADS)

Sit, Stefany M.; Brudzinski, Michael R.

2017-12-01

The recent emphasis in higher education on both student engagement and online learning encouraged the authors to develop an active e-learning environment for an introductory geohazards course, which enrolls 70+ undergraduate students per semester. Instructors focused on replicating the achievements and addressing the challenges within an already established face-to-face student-centered class (Brudzinski and Sikorski 2010; Sit 2013). Through the use of a learning management system (LMS) and other available technologies, a wide range of course components were developed including online homework assignments with automatic grading and tailored feedback, video tutorials of software programs like Google Earth and Microsoft Excel, and more realistic scientific investigations using authentic and freely available data downloaded from the internet. The different course components designed to engage students and improve overall student learning and development were evaluated using student surveys and instructor reflection. Each component can be used independently and intertwined into a face-to-face course. Results suggest that significant opportunities are available in an online environment including the potential for improved student performance and new datasets for educational research. Specifically, results from pre and post-semester Geoscience Concept Inventory (GCI) testing in an active e-learning course show enhanced student learning gains compared to face-to-face lecture-based and student-centered courses.

Mocetinostat combined with gemcitabine for the treatment of leiomyosarcoma: Preclinical correlates

PubMed Central

Braggio, Danielle; Zewdu, Abeba; Casadei, Lucia; Batte, Kara; Bid, Hemant Kumar; Koller, David; Yu, Peter; Iwenofu, Obiajulu Hans; Strohecker, Anne; Choy, Edwin; Lev, Dina; Pollock, Raphael

2017-01-01

Leiomyosarcoma (LMS) is a malignant soft tissue sarcoma (STS) with a dismal prognosis following metastatic disease. Chemotherapeutic intervention has demonstrated to have modest clinical efficacy with no curative potential in LMS patients. Previously, we demonstrated pan-HDAC inhibition to have a superior effect in various complex karyotypic sarcomas. In this study, our goal is to evaluate the therapeutic efficacy of mocetinostat alone and in combination with gemcitabine in LMS. Human leiomyosarcoma (LMS) cell lines were used for in vitro and in vivo studies. Compounds tested included the class I HDAC inhibitor, mocetinostat, and nucleoside analog, gemcitabine. MTS and clonogenic assays were used to evaluate the effect of mocetinostat on LMS cell growth. Cleaved caspase 3/7 analysis was used to determine the effects of mocetinostat on apoptosis. Compusyn software was used to determine in vitro synergy studies for the combination of mocetinostat plus gemcitabine. A LMS xenograft model in SCID mice was used to test the impact of mocetinostat alone, gemcitabine alone and the combination of mocetinostat plus gemcitabine. Mocetinostat abrogated LMS cell growth and clonogenic potential, and enhanced apoptosis in LMS cell lines. The combination of mocetinostat plus gemcitabine exhibited a synergistic effect in LMS cells in vitro. Similarly, mocetinostat combined with gemcitabine resulted in superior anti-LMS effects in vivo. Mocetinostat reduced the expression of gemcitabine-resistance markers RRM1, RRM2, and increased the expression of gemcitabine-sensitivity marker, hENT1, in LMS cells. LMS are aggressive, metastatic tumors with poor prognosis where effective therapeutic interventions are wanting. Our studies demonstrate the potential utility of mocetinostat combined with gemcitabine for the treatment of LMS. PMID:29186204

Selective recurrent laryngeal nerve stimulation using a penetrating electrode array in the feline model.

PubMed

Haidar, Yarah M; Sahyouni, Ronald; Moshtaghi, Omid; Wang, Beverly Y; Djalilian, Hamid R; Middlebrooks, John C; Verma, Sunil P; Lin, Harrison W

2017-10-31

Laryngeal muscles (LMs) are controlled by the recurrent laryngeal nerve (RLN), injury of which can result in vocal fold (VF) paralysis (VFP). We aimed to introduce a bioelectric approach to selective stimulation of LMs and graded muscle contraction responses. Acute experiments in cats. The study included six anesthetized cats. In four cats, a multichannel penetrating microelectrode array (MEA) was placed into an uninjured RLN. For RLN injury experiments, one cat received a standardized hemostat-crush injury, and one cat received a transection-reapproximation injury 4 months prior to testing. In each experiment, three LMs (thyroarytenoid, posterior cricoarytenoid, and cricothyroid muscles) were monitored with an electromyographic (EMG) nerve integrity monitoring system. Electrical current pulses were delivered to each stimulating channel individually. Elicited EMG voltage outputs were recorded for each muscle. Direct videolaryngoscopy was performed for visualization of VF movement. Stimulation through individual channels led to selective activation of restricted nerve populations, resulting in selective contraction of individual LMs. Increasing current levels resulted in rising EMG voltage responses. Typically, activation of individual muscles was successfully achieved via single placement of the MEA by selection of appropriate stimulation channels. VF abduction was predominantly observed on videolaryngoscopy. Nerve histology confirmed injury in cases of RLN crush and transection experiments. We demonstrated the ability of a penetrating MEA to selectively stimulate restricted fiber populations within the feline RLN and selectively elicit contractions of discrete LMs in both acute and injury-model experiments, suggesting a potential role for intraneural MEA implantation in VFP management. NA Laryngoscope, 2017. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.

Mobile Technology for Empowering Health Workers in Underserved Communities: New Approaches to Facilitate the Elimination of Neglected Tropical Diseases.

PubMed

Stanton, Michelle; Molineux, Andrew; Mackenzie, Charles; Kelly-Hope, Louise

2016-01-01

As global mobile phone penetration increases, direct health information communication from hard-to-reach communities is becoming commonplace. Mobile health (mHealth) tools that enable disease control programs to benefit from this information, while simultaneously empowering community members to take control of their own health, are vital to the goal of universal health care. Our aim was to highlight the development of the Liverpool mHealth Suite (LMS), which has been designed to address this need and improve health services for neglected tropical diseases being targeted for global elimination, such as lymphatic filariasis. The LMS has two main communication approaches-short message service and mobile phone apps-to facilitate real-time mass drug administration (MDA) coverage, reporting patient numbers, managing stock levels of treatment supplies, and exchanging health information to improve the quality of care of those affected. The LMS includes the MeasureSMS-MDA tool to improve drug supplies and MDA coverage rates in real-time (currently being trialed in urban Tanzania); the MeasureSMS-Morbidity tool to map morbidity, including lymphedema and hydrocele cases (initially piloted in rural Malawi and Ghana, then extended to Ethiopia, and scaled up to large urban areas in Bangladesh and Tanzania); the LyMSS-lymphedema management supply system app to improve distribution of treatments (trialed for 6 months in Malawi with positive impacts on health workers and patients); and the HealthFront app to improve education and training (in development with field trials planned). The current success and scale-up of the LMS by many community health workers in rural and urban settings across Africa and Asia highlights the value of this simple and practical suite of tools that empowers local health care workers to contribute to local, national, and global elimination of disease.

Comparison between retroperitoneal leiomyosarcoma and dedifferentiated liposarcoma.

PubMed

Ishii, Takeaki; Kohashi, Kenichi; Ootsuka, Hiroshi; Iura, Kunio; Maekawa, Akira; Yamada, Yuichi; Bekki, Hirofumi; Yoshimoto, Masato; Yamamoto, Hidetaka; Iwamoto, Yukihide; Oda, Yoshinao

2017-06-01

It is important to distinguish between leiomyosarcoma (LMS) and dedifferentiated liposarcoma (DDLS) in the retroperitoneum. The dedifferentiated component of DDLS shows an LMS-like morphology in some cases; thus, detailed evaluation is necessary to achieve an accurate diagnosis. Immunohistochemically, MDM2 and myogenic markers provide clues for the diagnoses. However, immunoreactivity for MDM2 and myogenic markers has not been well studied in retroperitoneal LMS and DDLS. Here, we compared the clinicopathological data of 20 retroperitoneal tumors initially diagnosed as LMS with that of 36 cases of retroperitoneal DDLS and conducted an immunohistochemical study. Four (20%) of the cases initially diagnosed as LMS were immunoreactive for MDM2. Fifteen cases (41.7%) of DDLS showed positive expression of two or more myogenic markers. The patients with LMS with MDM2 overexpression were older than the patients with LMS without MDM2 overexpression (P=0.0328). LMS with MDM2 overexpression showed a worse prognosis than DDLS (P=0.0408). No significant difference in prognosis was found between LMS without MDM2 overexpression and DDLS with myogenic differentiation. In conclusion, we recommend that systemic MDM2 expression analysis be performed in cases of retroperitoneal sarcoma. Overdependence on the expression of myogenic markers could lead to misdiagnosis in distinguishing LMS from DDLS. Copyright © 2017 Elsevier GmbH. All rights reserved.

Revisions of the Learning Mastery Systems for the Harper and Row Grades One and Two and the Macmillan Bank Street Grade One Reading Series.

ERIC Educational Resources Information Center

Maeder, Jacqueline; And Others

The revisions on the Learning Mastery Systems (LMSs) for the Harper & Row grade-one and grade-two and the Macmillan Bank Street grade-one reading programs are outlined in this document. A rationale for the revisions is presented. An LMS is a set of materials and procedures prepared by the southwest Regional Laboratory (SWRL) as an…

Moodle 2.0 Web Services Layer and Its New Application Contexts

NASA Astrophysics Data System (ADS)

Conde, Miguel Ángel; Aguilar, Diego Alonso Gómez; Del Pozo de Dios, Alberto; Peñalvo, Francisco José García

Owing to the intrinsic relation among actual education and new technologies, it results essential the fact to found the new ways to satisfy both sides of the modern eLearning platforms, the needs of students and tutors and the enough technologies to support it. Consequently, the possibility to interconnect the LMS with other external applications to enrich and strengthen the comprehension of learning process is one of the principal paths to follow.

Down-regulation of polycystin in lymphatic malformations: possible role in the proliferation of lymphatic endothelial cells.

PubMed

Ren, Jian-Gang; Xia, Hou-Fu; Yang, Jie-Gang; Zhu, Jun-Yi; Zhang, Wei; Chen, Gang; Zhao, Ji-Hong; Sun, Yan-Fang; Zhao, Yi-Fang

2017-07-01

Lymphatic malformations (LMs) are composed of aberrant lymphatic vessels and regarded as benign growths of the lymphatic system. Recent studies have demonstrated that the mutant embryos of PKD1 and PKD2, encoding polycystin-1 (PC-1) and polycystin-2 (PC-2), respectively, result in aberrant lymphatic vessels similar to those observed in LMs. In this study, for the first time, we investigated PC-1 and PC-2 expression and assessed their roles in the development of LMs. Our results demonstrated that PC-1 and PC-2 gene and protein expressions were obviously decreased in LMs compared with normal skin tissues. In addition, the expression of phosphorylated ERK but not total ERK was up-regulated in LMs and negatively correlated with the expression of PC-1 and PC-2. Moreover, up-regulation of Ki67 was detected in LMs and positively correlated with ERK phosphorylation levels. Furthermore, cluster analysis better reflected close correlation between these signals. All of the above results provided strong evidence suggesting that the hyperactivation of the ERK pathway may be caused by down-regulation of PC-1 and PC-2 in LMs, contributing to increased proliferation of lymphatic endothelial cells in LMs. Our present study sheds light on novel potential mechanisms involved in LMs and may help to explore novel treatments for LMs. Copyright © 2017 Elsevier Inc. All rights reserved.

A kernel adaptive algorithm for quaternion-valued inputs.

PubMed

Paul, Thomas K; Ogunfunmi, Tokunbo

2015-10-01

The use of quaternion data can provide benefit in applications like robotics and image recognition, and particularly for performing transforms in 3-D space. Here, we describe a kernel adaptive algorithm for quaternions. A least mean square (LMS)-based method was used, resulting in the derivation of the quaternion kernel LMS (Quat-KLMS) algorithm. Deriving this algorithm required describing the idea of a quaternion reproducing kernel Hilbert space (RKHS), as well as kernel functions suitable with quaternions. A modified HR calculus for Hilbert spaces was used to find the gradient of cost functions defined on a quaternion RKHS. In addition, the use of widely linear (or augmented) filtering is proposed to improve performance. The benefit of the Quat-KLMS and widely linear forms in learning nonlinear transformations of quaternion data are illustrated with simulations.

Same Mission, Different Look: Modernizing the AMS DataStreme Project

NASA Astrophysics Data System (ADS)

Abshire, W. E.; Kauffman, C.; Nugnes, K. A.; Geer, I. W.; Mills, E. W.; Stimach, A. E.

2017-12-01

For more than 20 years, the American Meteorological Society (AMS) has been enhancing K-12 teacher preparation and practice, and ultimately student learning through the DataStreme Project. DataStreme Atmosphere, Ocean, and Earth's Climate System (ECS), which are in close alignment with NGSS, empower teachers to implement STEM concepts in their classrooms using real-world data to deepen understanding of core science concepts and raise scientific literacy. For example, DataStreme ECS participants use the AMS Conceptual Climate Energy Model (CCEM) to explore radiative equilibrium. Then, participants use real-world NOAA data within the AMS Climate at a Glance (CAG) app to determine whether or not there is objective evidence consistent with climate change. Both the CCEM and CAG app enable participants to investigate concepts as scientists do, thereby aligning with Dimension 1 of NGSS. This presentation will highlight other ways in which DataStreme ECS aligns with the four disciplinary areas of NGSS. DataStreme courses are offered each fall and spring semester by Local Implementation Teams (LITs) across the country in coordination with AMS Education Program scientists and educators. In 2017, the AMS Education Program entered into a new agreement with California University of Pennsylvania to serve as their institutional partner for DataStreme to offer tuition-free graduate credits to participants. Some changes have already occurred and there are many opportunities for further enhancement. Most noticeably to begin, DataStreme course resources are now available to participants in all 50 states and U.S. territories through a learning management system (LMS). The use of a LMS enables LITs the opportunity to better engage their participants through online discussion boards, video assignments, shared dropbox uploads, digital assessment tools and rubrics, and much more. The Fall 2017 semester was the first term to exploit the Desire to Learn (D2L) platform for course implementation. This presentation will include feedback and lessons learned from early use of new pedagogical tools. The future of teacher professional development opportunities via AMS DataStreme courses is bright as it evolves under new leadership and leverages new tools while staying rooted in its mission to increase public scientific literacy.

Wikis in Collaborative Educational Scenarios: Integrated in LMS or Standalone Wikis?

ERIC Educational Resources Information Center

Forment, Marc Alier; De Pedro, Xavier; Casan, Maria Jose; Piguillem, Jordi; Galanis, Nikolas

2012-01-01

This article outlines a set of features that wiki engines require to successfully host collaborative educational scenarios. The authors explore multiple issues that deal with the use wikis with learning activities. One of the first issues to solve is software support for assessment methodologies. The second is choosing between using an integrated…

Transfer of Materials from Water to Solid Surfaces Using Liquid Marbles.

PubMed

Kawashima, Hisato; Paven, Maxime; Mayama, Hiroyuki; Butt, Hans-Jürgen; Nakamura, Yoshinobu; Fujii, Syuji

2017-09-27

Remotely controlling the movement of small objects is desirable, especially for the transportation and selection of materials. Transfer of objects between liquid and solid surfaces and triggering their release would allow for development of novel material transportation technology. Here, we describe the remote transport of a material from a water film surface to a solid surface using quasispherical liquid marbles (LMs). A light-induced Marangoni flow or an air stream is used to propel the LMs on water. As the LMs approach the rim of the water film, gravity forces them to slide down the water rim and roll onto the solid surface. Through this method, LMs can be efficiently moved on water and placed on a solid surface. The materials encapsulated within LMs can be released at a specific time by an external stimulus. We analyzed the velocity, acceleration, and force of the LMs on the liquid and solid surfaces. On water, the sliding friction due to the drag force resists the movement of the LMs. On a solid surface, the rolling distance is affected by the surface roughness of the LMs.

Establishment and proteomic characterization of NCC-LMS1-C1, a novel cell line of primary leiomyosarcoma of the bone.

PubMed

Sakumoto, Marimu; Takahashi, Mami; Oyama, Rieko; Takai, Yoko; Kito, Fusako; Shiozawa, Kumiko; Qiao, Zhiwei; Yoshida, Akihiko; Endo, Makoto; Kawai, Akira; Kondo, Tadashi

2017-10-01

Leiomyosarcoma (LMS) is one of most aggressive mesenchymal malignancies that differentiate towards smooth muscle. The clinical outcome of LMS patients is poor; as such, there is an urgent need for novel therapeutic approaches. Experimental models such as patient-derived cell lines are invaluable tools for pre-clinical studies. In the present study, we established a stable cell line from the tumor tissue of a patient with a primary LMS of the bone. Despite the urgent need for novel therapeutic strategies in LMS, there are only a few LMS cell lines available in public cell banks, none of which are primary to the bone. Bone primary LMS tumor tissues were sampled to establish cell lines. Morphological and proteomic analyses were performed and sensitivity to pazopanib was evaluated. NCC-LMS1-C1 cells were maintained for over 100 passages. The cells exhibited a spindle shape and aggressive growth; they also expressed smooth muscle actin, reflecting the original LMS tissue (i.e. smooth muscle cells). The cells also showed tumor characteristics such as colony formation on soft agar and sensitivity to pazopanib, doxorubicin and cisplatin, with half-maximal inhibitory concentrations of 4.5, 0.11 and 20 μM, respectively. Proteomic analyses by mass spectrometry and antibody array revealed some differences in the protein expression profiles of these cells as compared to the original tumor tissue. Our results indicate that the NCC-LMS1-C1 cell lines will be useful for LMS research. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

47 CFR 90.353 - LMS operations in the 902-928 MHz band.

Code of Federal Regulations, 2012 CFR

2012-10-01

... band. (b) LMS systems are authorized to transmit status and instructional messages, either voice or non-voice, so long as they are related to the location or monitoring functions of the system. (c) LMS... subparts B and C of this part. (d) Multilateration LMS systems will be authorized on a primary basis within...

47 CFR 90.353 - LMS operations in the 902-928 MHz band.

Code of Federal Regulations, 2010 CFR

2010-10-01

... band. (b) LMS systems are authorized to transmit status and instructional messages, either voice or non-voice, so long as they are related to the location or monitoring functions of the system. (c) LMS... subparts B and C of this part. (d) Multilateration LMS systems will be authorized on a primary basis within...

47 CFR 90.353 - LMS operations in the 902-928 MHz band.

Code of Federal Regulations, 2011 CFR

2011-10-01

... band. (b) LMS systems are authorized to transmit status and instructional messages, either voice or non-voice, so long as they are related to the location or monitoring functions of the system. (c) LMS... subparts B and C of this part. (d) Multilateration LMS systems will be authorized on a primary basis within...

47 CFR 90.353 - LMS operations in the 902-928 MHz band.

Code of Federal Regulations, 2014 CFR

2014-10-01

... band. (b) LMS systems are authorized to transmit status and instructional messages, either voice or non-voice, so long as they are related to the location or monitoring functions of the system. (c) LMS... subparts B and C of this part. (d) Multilateration LMS systems will be authorized on a primary basis within...

47 CFR 90.353 - LMS operations in the 902-928 MHz band.

Code of Federal Regulations, 2013 CFR

2013-10-01

... band. (b) LMS systems are authorized to transmit status and instructional messages, either voice or non-voice, so long as they are related to the location or monitoring functions of the system. (c) LMS... subparts B and C of this part. (d) Multilateration LMS systems will be authorized on a primary basis within...

Fast ultrasound-assisted synthesis of Li2MnSiO4 nanoparticles for a lithium-ion battery

NASA Astrophysics Data System (ADS)

Hwang, Chahwan; Kim, Taejin; Shim, Joongpyo; Kwak, Kyungwon; Ok, Kang Min; Lee, Kyung-Koo

2015-10-01

High-capacity Li2MnSiO4/C (LMS/C MBS) nanoparticles have been prepared using sonochemistry under a multibubble sonoluminescence (MBS) condition, and their physical and electrochemical properties were characterized. The results show that LMS/C MBS nanoparticles exhibit a nearly pure crystalline phase with orthorhombic structure and have a spherical shape and a uniform particle size distribution centered at a diameter of 22.5 nm. Galvanostatic charge-discharge measurements reveal that LMS/C MBS delivers an initial discharge capacity of about 260 mA h g-1 at a current rate of 16.5 mA g-1 in the voltage range of 1.5-4.8 V (vs. Li/Li+), while LMS MBS (LMS without a carbon source under MBS) and LMS/C SG (LMS with a carbon source using the conventional sol-gel method) possess lower capacities of 168 and 9 mA h g-1, respectively. The improved electrochemical performance of LMS/C MBS can be ascribed to the uniform nanoparticle size, mesoporous structure, and in-situ carbon coating, which can enhance the electronic conductivity as well as the lithium ion diffusion coefficient.

Performance study of LMS based adaptive algorithms for unknown system identification

NASA Astrophysics Data System (ADS)

Javed, Shazia; Ahmad, Noor Atinah

2014-07-01

Adaptive filtering techniques have gained much popularity in the modeling of unknown system identification problem. These techniques can be classified as either iterative or direct. Iterative techniques include stochastic descent method and its improved versions in affine space. In this paper we present a comparative study of the least mean square (LMS) algorithm and some improved versions of LMS, more precisely the normalized LMS (NLMS), LMS-Newton, transform domain LMS (TDLMS) and affine projection algorithm (APA). The performance evaluation of these algorithms is carried out using adaptive system identification (ASI) model with random input signals, in which the unknown (measured) signal is assumed to be contaminated by output noise. Simulation results are recorded to compare the performance in terms of convergence speed, robustness, misalignment, and their sensitivity to the spectral properties of input signals. Main objective of this comparative study is to observe the effects of fast convergence rate of improved versions of LMS algorithms on their robustness and misalignment.

Performance study of LMS based adaptive algorithms for unknown system identification

DOE Office of Scientific and Technical Information (OSTI.GOV)

Javed, Shazia; Ahmad, Noor Atinah

Adaptive filtering techniques have gained much popularity in the modeling of unknown system identification problem. These techniques can be classified as either iterative or direct. Iterative techniques include stochastic descent method and its improved versions in affine space. In this paper we present a comparative study of the least mean square (LMS) algorithm and some improved versions of LMS, more precisely the normalized LMS (NLMS), LMS-Newton, transform domain LMS (TDLMS) and affine projection algorithm (APA). The performance evaluation of these algorithms is carried out using adaptive system identification (ASI) model with random input signals, in which the unknown (measured) signalmore » is assumed to be contaminated by output noise. Simulation results are recorded to compare the performance in terms of convergence speed, robustness, misalignment, and their sensitivity to the spectral properties of input signals. Main objective of this comparative study is to observe the effects of fast convergence rate of improved versions of LMS algorithms on their robustness and misalignment.« less

A rare case of leiomyosarcoma originating from the left round ligament of the uterus.

PubMed

Kaba, Metin; Tokmak, Aytekin; Timur, Hakan; Özdal, Bülent; Şirvan, Levent; Güngör, Tayfun

2016-07-01

Uterine leiomyosarcomas (LMS) are rare malignancies with a poor prognosis. The incidence is reported to be 3-7/100.000 per year. Preoperative and intraoperative differentiation between LMS and large leiomyoma is always challenging. Therefore, LMS are often diagnosed during postoperative histologic evaluation of hysterectomy or myomectomy specimens. LMS of the round ligament of the uterus which can represent as an inguinal or pelvic mass is extremely rare. To our knowledge, there is only one case report of LMS arising from the round ligament available in the literature. Herein, we aimed to present the second case of LMS originating from the left round ligament of the uterus in a premenopausal woman initially misdiagnosed as an ovarian tumor. © 2016 Old City Publishing, Inc.

GeoGebra Materials for LMS Moodle Focused Monge on Projection

ERIC Educational Resources Information Center

Ferdiánová, Vera

2017-01-01

"The use of e-learning and modern technologies is an integral part of teaching descriptive geometry" (Rankowski and Minaruth, 1979). Teachers often create Flash animations, websites and other interactive materials for their students using special tools and software; e.g. Cabri, GeoGebra or Construct 3D (García et al, 2007). There is an…

Leiomyosarcoma: One disease or distinct biologic entities based on site of origin?

PubMed

Worhunsky, David J; Gupta, Mihir; Gholami, Sepideh; Tran, Thuy B; Ganjoo, Kristen N; van de Rijn, Matt; Visser, Brendan C; Norton, Jeffrey A; Poultsides, George A

2015-06-01

Leiomyosarcoma (LMS) can originate from the retroperitoneum, uterus, extremity, and trunk. It is unclear whether tumors of different origin represent discrete entities. We compared clinicopathologic features and outcomes following surgical resection of LMS stratified by site of origin. Patients with LMS undergoing resection at a single institution were retrospectively reviewed. Clinicopathologic variables were compared across sites. Survival was calculated using the Kaplan-Meier method and compared using log-rank and Cox regression analyses. From 1983 to 2011, 138 patients underwent surgical resection for LMS. Retroperitoneal and uterine LMS were larger, higher grade, and more commonly associated with synchronous metastases. However, disease-specific survival, recurrence-free survival, and recurrence patterns were not significantly different across the four sites. Synchronous metastases (HR 3.20, P < 0.001), but not site of origin, size, grade, or margin status, were independently associated with worse DSS. A significant number of recurrences and disease-related deaths were noted beyond 5 years. Although larger and higher grade, retroperitoneal and uterine LMS share similar survival and recurrence patterns with their trunk and extremity counterparts. LMS of various anatomic sites may not represent distinct disease processes based on clinical outcomes. The presence of metastatic disease remains the most important prognostic factor for LMS. © 2015 Wiley Periodicals, Inc.

Molecular analyses of 6 different types of uterine smooth muscle tumors: Emphasis in atypical leiomyoma.

PubMed

Zhang, Qing; Ubago, Julianne; Li, Li; Guo, Haiyang; Liu, Yugang; Qiang, Wenan; Kim, J Julie; Kong, Beihua; Wei, Jian-Jun

2014-10-15

Uterine smooth muscle tumors (USMTs) constitute a group of histologic, genetic, and clinical heterogeneous tumors that include at least 6 major histologically defined tumor types: leiomyoma (ULM), mitotically active leiomyoma (MALM), cellular leiomyoma (CLM), atypical leiomyoma (ALM), uncertain malignant potential (STUMP), and leiomyosarcoma (LMS). Apart from ULM and LMS, the nature of these variants is not well defined. A total of 167 cases of different USMT variants were collected, reviewed, and diagnostically confirmed based on the World Health Organization and Stanford schemes. These included 38 cases of LMS, 18 cases of STUMP, 42 cases of ALM, 22 cases of CLM, 7 cases of MALM, and 40 cases of ULM. Molecular analysis included selected microRNAs (miRNAs), oncogenes, and tumor suppressors that are highly relevant to USMT. Overall, 49% (17/35) of LMS cases and 7% (1/14) of STUMP cases died due to their USMT, but no deaths were attributed to ALM. miRNA profiling revealed that ALM and LMS shared similar miRNA signatures. P53 mutations and PTEN deletions were significantly higher in LMS, ALM, and STUMP compared with other USMT variants (P < .01). In contrast, MED12 mutations were extremely common in ULM and MALM (> 74%) but were significantly less common (< 15%) in CLM, ALM, STUMP, and LMS (P < .01). Six types of USMT have different gene mutation fingerprints. ALM shares many molecular alterations with LMS. Our findings suggest that ALM may be a precursor lesion of LMS or have similar genetic changes during its early stage. © 2014 American Cancer Society.

Counter-propagation network with variable degree variable step size LMS for single switch typing recognition.

PubMed

Yang, Cheng-Huei; Luo, Ching-Hsing; Yang, Cheng-Hong; Chuang, Li-Yeh

2004-01-01

Morse code is now being harnessed for use in rehabilitation applications of augmentative-alternative communication and assistive technology, including mobility, environmental control and adapted worksite access. In this paper, Morse code is selected as a communication adaptive device for disabled persons who suffer from muscle atrophy, cerebral palsy or other severe handicaps. A stable typing rate is strictly required for Morse code to be effective as a communication tool. This restriction is a major hindrance. Therefore, a switch adaptive automatic recognition method with a high recognition rate is needed. The proposed system combines counter-propagation networks with a variable degree variable step size LMS algorithm. It is divided into five stages: space recognition, tone recognition, learning process, adaptive processing, and character recognition. Statistical analyses demonstrated that the proposed method elicited a better recognition rate in comparison to alternative methods in the literature.

A new double digestion ligation mediated suppression PCR method for simultaneous bacteria DNA-typing and confirmation of species: an Acinetobacter sp. model.

PubMed

Stojowska, Karolina; Krawczyk, Beata

2014-01-01

We have designed a new ddLMS PCR (double digestion Ligation Mediated Suppression PCR) method based on restriction site polymorphism upstream from the specific target sequence for the simultaneous identification and differentiation of bacterial strains. The ddLMS PCR combines a simple PCR used for species or genus identification and the LM PCR strategy for strain differentiation. The bacterial identification is confirmed in the form of the PCR product(s), while the length of the PCR product makes it possible to differentiate between bacterial strains. If there is a single copy of the target sequence within genomic DNA, one specific PCR product is created (simplex ddLMS PCR), whereas for multiple copies of the gene the fingerprinting patterns can be obtained (multiplex ddLMS PCR). The described ddLMS PCR method is designed for rapid and specific strain differentiation in medical and microbiological studies. In comparison to other LM PCR it has substantial advantages: enables specific species' DNA-typing without the need for pure bacterial culture selection, is not sensitive to contamination with other cells or genomic DNA, and gives univocal "band-based" results, which are easy to interpret. The utility of ddLMS PCR was shown for Acinetobacter calcoaceticus-baumannii (Acb) complex, the genetically closely related and phenotypically similar species and also important nosocomial pathogens, for which currently, there are no recommended methods for screening, typing and identification. In this article two models are proposed: 3' recA-ddLMS PCR-MaeII/RsaI for Acb complex interspecific typing and 5' rrn-ddLMS PCR-HindIII/ApaI for Acinetobacter baumannii intraspecific typing. ddLMS PCR allows not only for DNA-typing but also for confirmation of species in one reaction. Also, practical guidelines for designing a diagnostic test based on ddLMS PCR for genotyping different species of bacteria are provided.

A New Double Digestion Ligation Mediated Suppression PCR Method for Simultaneous Bacteria DNA-Typing and Confirmation of Species: An Acinetobacter sp. Model

PubMed Central

Stojowska, Karolina; Krawczyk, Beata

2014-01-01

We have designed a new ddLMS PCR (double digestion Ligation Mediated Suppression PCR) method based on restriction site polymorphism upstream from the specific target sequence for the simultaneous identification and differentiation of bacterial strains. The ddLMS PCR combines a simple PCR used for species or genus identification and the LM PCR strategy for strain differentiation. The bacterial identification is confirmed in the form of the PCR product(s), while the length of the PCR product makes it possible to differentiate between bacterial strains. If there is a single copy of the target sequence within genomic DNA, one specific PCR product is created (simplex ddLMS PCR), whereas for multiple copies of the gene the fingerprinting patterns can be obtained (multiplex ddLMS PCR). The described ddLMS PCR method is designed for rapid and specific strain differentiation in medical and microbiological studies. In comparison to other LM PCR it has substantial advantages: enables specific species' DNA-typing without the need for pure bacterial culture selection, is not sensitive to contamination with other cells or genomic DNA, and gives univocal “band-based” results, which are easy to interpret. The utility of ddLMS PCR was shown for Acinetobacter calcoaceticus-baumannii (Acb) complex, the genetically closely related and phenotypically similar species and also important nosocomial pathogens, for which currently, there are no recommended methods for screening, typing and identification. In this article two models are proposed: 3′ recA-ddLMS PCR-MaeII/RsaI for Acb complex interspecific typing and 5′ rrn-ddLMS PCR-HindIII/ApaI for Acinetobacter baumannii intraspecific typing. ddLMS PCR allows not only for DNA-typing but also for confirmation of species in one reaction. Also, practical guidelines for designing a diagnostic test based on ddLMS PCR for genotyping different species of bacteria are provided. PMID:25522278

Effects of TiO2 addition on microwave dielectric properties of Li2MgSiO4 ceramics

NASA Astrophysics Data System (ADS)

Rose, Aleena; Masin, B.; Sreemoolanadhan, H.; Ashok, K.; Vijayakumar, T.

2018-03-01

Silicates have been widely studied for substrate applications in microwave integrated circuits owing to their low dielectric constant and low tangent loss values. Li2MgSiO4 (LMS) ceramics are synthesized through solid-state reaction route using TiO2 as an additive to the pure ceramics. Variations in dielectric properties of LMS upon TiO2 addition in different weight percentages (0.5, 1.5, 2) are studied by keeping the sintering parameters constant. Crystalline structure, phase composition, and microstructure of LMS and LMS-TiO2 ceramics were studied using x-ray diffraction spectrometer and High Resolution Scanning electron microscope. Density was measured through Archimedes method and the microwave dielectric properties were examined by Cavity perturbation technique. LMS achieved relative permittivity (ε r) of 5.73 and dielectric loss (tan δ) of 5.897 × 10‑4 at 8 GHz. In LMS-TiO2 ceramics, 0.5 wt% TiO2 added LMS showed comparatively better dielectric properties than other weight percentages where ε r = 5.67, tan δ = 7.737 × 10‑4 at 8 GHz.

Towards a mLearning training solution to the adoption of a CPOE system.

PubMed

Pakonstantinou, Despoina; Poulymenopoulou, Mikaela; Malamateniou, Flora; Vassilacopoulos, George

2012-01-01

Computerized Physician Order Entry (CPOE) has been introduced as a solution that can fundamentally change the way healthcare is provided, affecting all types of healthcare stakeholders and improving healthcare decisions, patient outcomes, patient safety and efficiency. However, a relatively small proportion of healthcare organizations have implemented CPOE systems, due to its technological complexity and to its low acceptance rate by healthcare professionals who largely disregard the value of CPOE in efficient healthcare delivery. An online training facility embedded within a CPOE service may increase the likelihood of its adoption by healthcare professionals as it offers them guidelines on how to perform each task of the CPOE service. In contrast to CPOE, on the other hand, handheld devices and other mobile technologies have showed an increased adoption rate. This paper considers a CPOE service that can be accessed by authorized healthcare professionals through their mobile devices anytime anywhere, and allows embedded training content, which has been developed through a learning management system (LMS) to be presented to the user automatically upon request.

Implementation of an Open Source Library Management System: Experiences with Koha 3.0 at the Royal London Homoeopathic Hospital

ERIC Educational Resources Information Center

Bissels, Gerhard

2008-01-01

Purpose: The purpose of this paper is to describe the selection process and criteria that led to the implementation of the Koha 3.0 library management system (LMS) at the Complementary and Alternative Medicine Library and Information Service (CAMLIS), Royal London Homoeopathic Hospital. Design/methodology/approach: The paper is a report based on…

Relationships between severity of chronic rhinosinusitis and nasal polyposis, asthma, and atopy

PubMed Central

Pearlman, Aaron N.; Chandra, Rakesh K.; Chang, Dennis; Conley, David B.; Peters, Anju Tripathi; Grammer, Leslie C.; Schleimer, Robert T.; Kern, Robert C.

2013-01-01

Background The effect of comorbid conditions such as asthma and atopy on the severity of chronic rhinosinusitis (CRS) and the presence of nasal polyps (NPs) remains an area of investigation. We sought to elucidate the relationship among these entities. Methods The study population included 106 consecutive patients who were referred to a multidisciplinary, university-based allergy and sinus clinic that underwent computed tomography (CT) scan, skin-prick testing, and had CRS. Data were analyzed to determine Lund-MacKay score (LMS), presence of NPs, asthma status, and sensitivity to seven classes of aeroallergens. Results Skin tests were positive in 52 cases and negative in 54 cases. Although, there was no statistical relationship between LMS and atopic status in the entire group, among the asthmatic subgroup, mean LMS was greater in nona topic asthmatic patients than in atopic asthmatic patients. Asthmatic patients had a higher LMS than nonasthmatic patients (p < 0.0001). Asthmatic patients were more likely than nonasthmatic patients to have NPs (57.6% versus 25%; p = 0.0015), regardless of atopic status. Mean LMS was higher in NP patients compared with nonpolyp patients (p < 0.0001), independent of atopic status. Mean LMS was not affected by sensitivity to any particular allergen, with the exception of cockroach-allergic patients who were more likely to have an LMS of >10 (p = 0.0236) and had more severe maxillary sinus involvement (p = 0.0391). Conclusion These data indicate a strong relationship between CRS severity, as measured by LMS, and chronic airway inflammatory diseases, asthma, and NPs. The association between LMS and atopic status appears weak. The present study suggests that CRS is an inflammatory disease that occurs independently of systemic IgE-mediated pathways. PMID:19401038

[Evaluation of the performance of the logistics management system of malaria control resources in the Littoral Department, Benin, in 2017].

PubMed

Ouro-Koura, Abdou-Rahim; Sopoh, Emmanuel Ghislain; Sossa, Jerôme Charles; Glèlè-Ahanhanzo, Yolaine; Agueh, Victoire; Ouendo, Edgard-Marius; Ouedraogo, Laurent

2018-01-01

This study aimed to evaluate the performance of the logistics management system (LMS) of malaria control (MC) resources in the Littoral Department, Benin, in 2017. In June 2017, we conducted a cross-sectional evaluative study focusing on the structures for the storage and the disposal of MC resources as well as on staff involved in their management. The performance of the the logistics management system was evaluated on the basis of the observed compliance of the components and sub-components of the "Structure", the "Process" and the "Results" with the norms and standards defined by the Ministry of Health. A total of 36 structures were investigated and secondary target was surveyed. It followed that 52,78% of the structures for the storage and the disposal of MC resources met the requirements for resources storage while only 33.33% of MC resources management staff were trained in logistics management. The performance of the logistics management system of MC resources was inadequate (compliance 59,13 % compared to the expected score). The structure, as well as the process were non-compliant with the standards ( 60,20% and 73.22% compared to the expected score respectively), leading to negative results (41.53% compared to the expected score). The most inadequate sub-component was the logistics management information system (LMIS). This study highlights the role of LMS for better performance of MC resources management. Particular attention should be given to this component.

Primary leiomyosarcoma in the colon

PubMed Central

Yang, Jing

2018-01-01

Abstract Rationale: Leiomyosarcoma (LMS) is a common type of soft tissue sarcoma. Primary colonic LMS in general is a very rare entity, accounting for 1% to 2% of gastrointestinal malignancies. Patient concerns: We report a case of 55-year-old female who presented with a sudden onset of sharp right lower quadrant abdominal pain. Electronic colonoscopy showed a normal lumen. However, an abdominal computed tomography scan revealed a mass of soft tissue attenuation inseparable from the ascending colon which appeared as a gastrointestinal stromal tumor (GIST). Diagnoses: It is important to diagnose LMS definitively by immunohistochemical profiling of smooth muscle actin, desmin, and CD34. Interventions: She underwent laparotomy and right hemicolectomy, and histology confirmed a colonic LMS. The patient received no oncological treatment after surgery. Outcomes: No recurrence or metastasis was observed at 5 months postoperatively. It is crucial to identify colonic LMS precisely based on immunohistochemistry, and thereby distinguish it from GIST. Lessons: Further investigation on LMS cases so far is required to establish standard treatment strategies. PMID:29443772

Simulation for noise cancellation using LMS adaptive filter

NASA Astrophysics Data System (ADS)

Lee, Jia-Haw; Ooi, Lu-Ean; Ko, Ying-Hao; Teoh, Choe-Yung

2017-06-01

In this paper, the fundamental algorithm of noise cancellation, Least Mean Square (LMS) algorithm is studied and enhanced with adaptive filter. The simulation of the noise cancellation using LMS adaptive filter algorithm is developed. The noise corrupted speech signal and the engine noise signal are used as inputs for LMS adaptive filter algorithm. The filtered signal is compared to the original noise-free speech signal in order to highlight the level of attenuation of the noise signal. The result shows that the noise signal is successfully canceled by the developed adaptive filter. The difference of the noise-free speech signal and filtered signal are calculated and the outcome implies that the filtered signal is approaching the noise-free speech signal upon the adaptive filtering. The frequency range of the successfully canceled noise by the LMS adaptive filter algorithm is determined by performing Fast Fourier Transform (FFT) on the signals. The LMS adaptive filter algorithm shows significant noise cancellation at lower frequency range.

Using the LMS method to calculate z-scores for the Fenton preterm infant growth chart.

PubMed

Fenton, T R; Sauve, R S

2007-12-01

The use of exact percentiles and z-scores permit optimal assessment of infants' growth. In addition, z-scores allow the precise description of size outside of the 3rd and 97th percentiles of a growth reference. To calculate percentiles and z-scores, health professionals require the LMS parameters (Lambda for the skew, Mu for the median, and Sigma for the generalized coefficient of variation; Cole, 1990). The objective of this study was to calculate the LMS parameters for the Fenton preterm growth chart (2003). Secondary data analysis of the Fenton preterm growth chart data. The Cole methods were used to produce the LMS parameters and to smooth the L parameter. New percentiles were generated from the smooth LMS parameters, which were then compared with the original growth chart percentiles. The maximum differences between the original percentile curves and the percentile curves generated from the LMS parameters were: for weight; a difference of 66 g (2.9%) at 32 weeks along the 90th percentile; for head circumference; some differences of 0.3 cm (0.6-1.0%); and for length; a difference of 0.5 cm (1.6%) at 22 weeks on the 97th percentile. The percentile curves generated from the smoothed LMS parameters for the Fenton growth chart are similar to the original curves. These LMS parameters for the Fenton preterm growth chart facilitate the calculation of z-scores, which will permit the more precise assessment of growth of infants who are born preterm.

e-Learning in Advanced Life Support-What factors influence assessment outcome?

PubMed

Thorne, C J; Lockey, A S; Kimani, P K; Bullock, I; Hampshire, S; Begum-Ali, S; Perkins, G D

2017-05-01

To establish variables which are associated with favourable Advanced Life Support (ALS) course assessment outcomes, maximising learning effect. Between 1 January 2013 and 30 June 2014, 8218 individuals participated in a Resuscitation Council (UK) e-learning Advanced Life Support (e-ALS) course. Participants completed 5-8h of online e-learning prior to attending a one day face-to-face course. e-Learning access data were collected through the Learning Management System (LMS). All participants were assessed by a multiple choice questionnaire (MCQ) before and after the face-to-face aspect alongside a practical cardiac arrest simulation (CAS-Test). Participant demographics and assessment outcomes were analysed. The mean post e-learning MCQ score was 83.7 (SD 7.3) and the mean post-course MCQ score was 87.7 (SD 7.9). The first attempt CAS-Test pass rate was 84.6% and overall pass rate 96.6%. Participants with previous ALS experience, ILS experience, or who were a core member of the resuscitation team performed better in the post-course MCQ, CAS-Test and overall assessment. Median time spent on the e-learning was 5.2h (IQR 3.7-7.1). There was a large range in the degree of access to e-learning content. Increased time spent accessing e-learning had no effect on the overall result (OR 0.98, P=0.367) on simulated learning outcome. Clinical experience through membership of cardiac arrest teams and previous ILS or ALS training were independent predictors of performance on the ALS course whilst time spent accessing e-learning materials did not affect course outcomes. This supports the blended approach to e-ALS which allows participants to tailor their e-learning experience to their specific needs. Copyright © 2017 Elsevier B.V. All rights reserved.

47 CFR 90.355 - LMS operations below 512 MHz.

Code of Federal Regulations, 2011 CFR

2011-10-01

... PRIVATE LAND MOBILE RADIO SERVICES Intelligent Transportation Systems Radio Service § 90.355 LMS... LMS station and the nearest co-channel base station of another licensee operating a voice system is 75... MHz, 150-170 MHz, and 450-512 MHz bands may use either base-mobile frequencies currently assigned the...

Investigation of Back-off Based Interpolation Between Recurrent Neural Network and N-gram Language Models (Author’s Manuscript)

DTIC Science & Technology

2016-02-11

INVESTIGATION OF BACK-OFF BASED INTERPOLATION BETWEEN RECURRENT NEURAL NETWORK AND N- GRAM LANGUAGE MODELS X. Chen, X. Liu, M. J. F. Gales, and P. C...As the gener- alization patterns of RNNLMs and n- gram LMs are inherently dif- ferent, RNNLMs are usually combined with n- gram LMs via a fixed...RNNLMs and n- gram LMs as n- gram level changes. In order to fully exploit the detailed n- gram level comple- mentary attributes between the two LMs, a

Quantile regression via vector generalized additive models.

PubMed

Yee, Thomas W

2004-07-30

One of the most popular methods for quantile regression is the LMS method of Cole and Green. The method naturally falls within a penalized likelihood framework, and consequently allows for considerable flexible because all three parameters may be modelled by cubic smoothing splines. The model is also very understandable: for a given value of the covariate, the LMS method applies a Box-Cox transformation to the response in order to transform it to standard normality; to obtain the quantiles, an inverse Box-Cox transformation is applied to the quantiles of the standard normal distribution. The purposes of this article are three-fold. Firstly, LMS quantile regression is presented within the framework of the class of vector generalized additive models. This confers a number of advantages such as a unifying theory and estimation process. Secondly, a new LMS method based on the Yeo-Johnson transformation is proposed, which has the advantage that the response is not restricted to be positive. Lastly, this paper describes a software implementation of three LMS quantile regression methods in the S language. This includes the LMS-Yeo-Johnson method, which is estimated efficiently by a new numerical integration scheme. The LMS-Yeo-Johnson method is illustrated by way of a large cross-sectional data set from a New Zealand working population. Copyright 2004 John Wiley & Sons, Ltd.

Communication in mental health nursing - Bachelor Students' appraisal of a blended learning training programme - an exploratory study.

PubMed

Furnes, Merete; Kvaal, Kari Sofie; Høye, Sevald

2018-01-01

It is important that mental health nursing students at Bachelor level obtain effective communication skills. Many students dread the fact that in the mental health field they will encounter patients and relatives with various backgrounds and personalities. Large classes and limited teaching resources in nursing education are challenging. To prepare students for mental health nursing practice, a communication skills course based on the blended learning method was developed and carried out at two different campuses.The aim of the study is to explore Bachelor nursing students' appraisal of blended learning methods for enhancing communication skills in mental health nursing. This study employed an exploratory design. Teaching and information materials were available on the learning management system (LMS). Videotaped role play training was carried out in the Simulation Department. Data were collected after the course by means of a questionnaire with closed and open-ended questions. The response rate was 59.2%. Quantitative data were analysed using the Statistical package for the Social Sciences (SPSS) and the Kruskal Wallis test, while qualitative data were analysed by content analysis based on Graneheim and Lundman's approach. No impact of background variables was observed. Students appreciated teachers' participation in role play and immediate feedback was considered especially important for learning outcomes. The students perceived that their communication skills and knowledge had improved after completing the blended learning programme. According to the nursing students, blended learning is an appropriate method for improving communication skills in preparation for mental health nursing. Blended learning makes it possible to build flexible courses with limited resources.

Superaligned carbon nanotube arrays, films, and yarns: a road to applications.

PubMed

Jiang, Kaili; Wang, Jiaping; Li, Qunqing; Liu, Liang; Li, Changhong; Fan, Shoushan

2011-03-04

A superaligned carbon nanotube (CNT) array is a special kind of vertically aligned CNT array with the capability of being converted into continuous fi lms and yarns. The as-produced CNT fi lms are transparent and highly conductive, with aligned CNTs parallel to the direction of drawing. After passing through volatile solutions or being twisted, CNT fi lms can be further condensed into shrunk yarns. These shrunk yarns possess high tensile strengths and Young’s moduli, and are good conductors. Many applications of CNT fi lms and shrunk yarns have been demonstrated, such as TEM grids, loudspeakers, touch screens, etc.

A novel method of language modeling for automatic captioning in TC video teleconferencing.

PubMed

Zhang, Xiaojia; Zhao, Yunxin; Schopp, Laura

2007-05-01

We are developing an automatic captioning system for teleconsultation video teleconferencing (TC-VTC) in telemedicine, based on large vocabulary conversational speech recognition. In TC-VTC, doctors' speech contains a large number of infrequently used medical terms in spontaneous styles. Due to insufficiency of data, we adopted mixture language modeling, with models trained from several datasets of medical and nonmedical domains. This paper proposes novel modeling and estimation methods for the mixture language model (LM). Component LMs are trained from individual datasets, with class n-gram LMs trained from in-domain datasets and word n-gram LMs trained from out-of-domain datasets, and they are interpolated into a mixture LM. For class LMs, semantic categories are used for class definition on medical terms, names, and digits. The interpolation weights of a mixture LM are estimated by a greedy algorithm of forward weight adjustment (FWA). The proposed mixing of in-domain class LMs and out-of-domain word LMs, the semantic definitions of word classes, as well as the weight-estimation algorithm of FWA are effective on the TC-VTC task. As compared with using mixtures of word LMs with weights estimated by the conventional expectation-maximization algorithm, the proposed methods led to a 21% reduction of perplexity on test sets of five doctors, which translated into improvements of captioning accuracy.

Evaluation of simulation learning materials use to fill the gap in Japanese dental English education.

PubMed

Seki, Naoko; Moross, Janelle; Sunaga, Masayo; Hobo, Koki; Miyoshi, Tomoe; Nitta, Hiroshi; Kinoshita, Atsuhiro; Morio, Ikuko

2016-01-01

Even though English is most frequently the common language when the patient's native language differs from that of a dentist, the opportunities for Japanese undergraduate dental students to learn dental English are now quite limited. The purposes of our study were to investigate: the effectiveness and feasibility of the computer-assisted simulation materials as one solution strategy for dental English education in Japan, and the needs and demands for dental English from the learners' side. Interactive simulation materials for medical interviews in English and clinical cases which were translated to English, were delivered via Learning Management System (LMS) to nineteen trainee residents of dentistry (residents). Evaluation for the materials, learners' knowledge and interests in the contents, and ease of operation were obtained by post-questionnaire (response rates were 100% and 95%, respectively). Both questionnaire-surveys received positive feedback toward the materials, yet 47% answered that they lacked the level of knowledge about contents of the medical interview in English. Results were sufficient to suggest that the residents would like to have the opportunity to study or practice medical interview in English, or English related to dentistry, and that the simulation materials could be one of the solution strategies for opportunity provision.

47 CFR 90.357 - Frequencies for LMS systems in the 902-928 MHz band.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 5 2010-10-01 2010-10-01 false Frequencies for LMS systems in the 902-928 MHz band. 90.357 Section 90.357 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Intelligent Transportation Systems Radio Service § 90.357 Frequencies for LMS systems in...

47 CFR 90.359 - Field strength limits for EA-licensed LMS systems.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 5 2011-10-01 2011-10-01 false Field strength limits for EA-licensed LMS... § 90.359 Field strength limits for EA-licensed LMS systems. EA-licensed multilateration systems shall limit the field strength of signals transmitted from their base stations to 47 dBuV/m at their EA...

Differentiation of Uterine Leiomyosarcoma from Atypical Leiomyoma: Diagnostic Accuracy of Qualitative MR Imaging Features and Feasibility of Texture Analysis.

PubMed

Lakhman, Yulia; Veeraraghavan, Harini; Chaim, Joshua; Feier, Diana; Goldman, Debra A; Moskowitz, Chaya S; Nougaret, Stephanie; Sosa, Ramon E; Vargas, Hebert Alberto; Soslow, Robert A; Abu-Rustum, Nadeem R; Hricak, Hedvig; Sala, Evis

2017-07-01

To investigate whether qualitative magnetic resonance (MR) features can distinguish leiomyosarcoma (LMS) from atypical leiomyoma (ALM) and assess the feasibility of texture analysis (TA). This retrospective study included 41 women (ALM = 22, LMS = 19) imaged with MRI prior to surgery. Two readers (R1, R2) evaluated each lesion for qualitative MR features. Associations between MR features and LMS were evaluated with Fisher's exact test. Accuracy measures were calculated for the four most significant features. TA was performed for 24 patients (ALM = 14, LMS = 10) with uniform imaging following lesion segmentation on axial T2-weighted images. Texture features were pre-selected using Wilcoxon signed-rank test with Bonferroni correction and analyzed with unsupervised clustering to separate LMS from ALM. Four qualitative MR features most strongly associated with LMS were nodular borders, haemorrhage, "T2 dark" area(s), and central unenhanced area(s) (p ≤ 0.0001 each feature/reader). The highest sensitivity [1.00 (95%CI:0.82-1.00)/0.95 (95%CI: 0.74-1.00)] and specificity [0.95 (95%CI:0.77-1.00)/1.00 (95%CI:0.85-1.00)] were achieved for R1/R2, respectively, when a lesion had ≥3 of these four features. Sixteen texture features differed significantly between LMS and ALM (p-values: <0.001-0.036). Unsupervised clustering achieved accuracy of 0.75 (sensitivity: 0.70; specificity: 0.79). Combination of ≥3 qualitative MR features accurately distinguished LMS from ALM. TA was feasible. • Four qualitative MR features demonstrated the strongest statistical association with LMS. • Combination of ≥3 these features could accurately differentiate LMS from ALM. • Texture analysis was a feasible semi-automated approach for lesion categorization.

Handover aspects for a Low Earth Orbit (LEO) CDMA Land Mobile Satellite (LMS) system

NASA Technical Reports Server (NTRS)

Carter, P.; Beach, M. A.

1993-01-01

This paper addresses the problem of handoff in a land mobile satellite (LMS) system between adjacent satellites in a low earth orbit (LEO) constellation. In particular, emphasis is placed on the application of soft handoff in a direct sequence code division multiple access (DS-CDMA) LMS system. Soft handoff is explained in terms of terrestrial macroscopic diversity, in which signals transmitted via several independent fading paths are combined to enhance the link quality. This concept is then reconsidered in the context of a LEO LMS system. A two-state Markov channel model is used to simulate the effects of shadowing on the communications path from the mobile to each satellite during handoff. The results of the channel simulation form a platform for discussion regarding soft handoff, highlighting the potential merits of the scheme when applied in a LEO LMS environment.

Fostering Teacher Understanding of Parent Issues when a Child Has a Disability: A Brief Report

ERIC Educational Resources Information Center

Wilgosh, Lorraine; Scorgie, Kate

2006-01-01

The paper reports on parent survey comments to raise awareness of teachers of children with disabilities and facilitate the parent-teacher collaborative experience. The Life Management Survey (LMS) was designed (Scorgie, Wilgosh, & McDonald, 1997) to corroborate nine themes (Scorgie, Wilgosh, & McDonald, 1996) identified through in-depth…

A generalized leaky FxLMS algorithm for tuning the waterbed effect of feedback active noise control systems

NASA Astrophysics Data System (ADS)

Wu, Lifu; Qiu, Xiaojun; Guo, Yecai

2018-06-01

To tune the noise amplification in the feedback system caused by the waterbed effect effectively, an adaptive algorithm is proposed in this paper by replacing the scalar leaky factor of the leaky FxLMS algorithm with a real symmetric Toeplitz matrix. The elements in the matrix are calculated explicitly according to the noise amplification constraints, which are defined based on a simple but efficient method. Simulations in an ANC headphone application demonstrate that the proposed algorithm can adjust the frequency band of noise amplification more effectively than the FxLMS algorithm and the leaky FxLMS algorithm.

Improving the Response of Accelerometers for Automotive Applications by Using LMS Adaptive Filters: Part II

PubMed Central

Hernandez, Wilmar; de Vicente, Jesús; Sergiyenko, Oleg Y.; Fernández, Eduardo

2010-01-01

In this paper, the fast least-mean-squares (LMS) algorithm was used to both eliminate noise corrupting the important information coming from a piezoresisitive accelerometer for automotive applications, and improve the convergence rate of the filtering process based on the conventional LMS algorithm. The response of the accelerometer under test was corrupted by process and measurement noise, and the signal processing stage was carried out by using both conventional filtering, which was already shown in a previous paper, and optimal adaptive filtering. The adaptive filtering process relied on the LMS adaptive filtering family, which has shown to have very good convergence and robustness properties, and here a comparative analysis between the results of the application of the conventional LMS algorithm and the fast LMS algorithm to solve a real-life filtering problem was carried out. In short, in this paper the piezoresistive accelerometer was tested for a multi-frequency acceleration excitation. Due to the kind of test conducted in this paper, the use of conventional filtering was discarded and the choice of one adaptive filter over the other was based on the signal-to-noise ratio improvement and the convergence rate. PMID:22315579

Integration of the e-Learning into the medical university curricula.

PubMed

Rusnakova, V; Bacharova, L; Simo, J; Krcmeryova, T; Finka, M; Kovac, R

2012-01-01

The aim of this contribution was to present the e-Learning introduction in the Slovak Medical University (SMU) with a focus on the implementation phase of the two blended courses - Healthcare Quality and Healthcare Professionals' Ethics. The introduction of the e-Learning was realized during the period 2008-2009 in the partnership of SMU and IBM Company, following strictly the project management approach. The development of the e-module beta-versions was evaluated by the modules' authors using a structured interview. In a consequent pilot testing, the blended courses were evaluated by 23 students of the bachelor program in Rescue health care, and by 61 public health students at the master level program, respectively, using the standardized questionnaires. The tangible results included the documented SMU strategy for the e-Learning integration, six e-Learning modules and evaluation results. The authors' evaluation showed high scores for the experience in collaboration with IBM, as well as for the experience with the LMS environment. The students' evaluation showed a high acceptance of the e-Learning by both part-time and full-time students. The access to Internet was not recognized as a serious barrier. The first experience with the integration of the e-Learning into the curricula of the Slovak Medical University showed the advantage of the systematic approach. The experience with developing the strategy in an interdisciplinary/ intercultural team, the knowledge about specific characteristics of distance learning by the involved SMU staff, and the know-how and skills represented the important benefits. It was demonstrated that the blended learning is recommended as optimal for the education in medical environment (Tab. 4, Fig. 1, Ref. 22).

Recent Advances in Liquid Metal Manipulation toward Soft Robotics and Biotechnologies.

PubMed

Yu, Yue; Miyako, Eijiro

2018-04-06

Interest has grown significantly in the field of soft robotics, which seeks to develop machinery capable of duplicating the elastic and rheological properties of typically polymeric or elastomeric biological tissues and organs. As a result of a number of unique properties, gallium-based liquid metals (LMs) are emerging as materials used in the forefront of soft robotics research. Finding methods to enable the sophisticated manipulation of LMs will be essential for further progress in the field. This review provides a critical discussion of the manipulation of LMs and on important biotechnological applications of LMs including microfluidics, healthcare devices, biomaterials, and nanomedicines. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Two Years on: Koha 3.0 in Use at the CAMLIS Library, Royal London Homoeopathic Hospital

ERIC Educational Resources Information Center

Bissels, Gerhard; Chandler, Andrea

2010-01-01

Purpose: The purpose of this paper is to describe the further development of the Koha 3.0 library management system (LMS) and the involvement of external software consultants at the Complementary and Alternative Medicine Library and Information Service (CAMLIS), Royal London Homoeopathic Hospital. Design/methodology/approach: The paper takes the…

EMMPRIN (CD147) Expression in Smooth Muscle Tumors of the Uterus.

PubMed

Kefeli, Mehmet; Yildiz, Levent; Gun, Seda; Ozen, Fatma Z; Karagoz, Filiz

2016-01-01

Smooth muscle tumors of the uterus are the most common mesenchymal tumors of the gynecologic tract. The vast majority of these are benign leiomyomas that present no diagnostic difficulty. Because some benign smooth muscle tumors may degenerate and uncommon variants exist, the diagnosis can be challenging in some cases. The goal of this research was to investigate EMMPRIN expression in leiomyomas, leiomyoma variants, and leiomyosarcomas (LMS) to determine whether it has a potential role in differential diagnosis. EMMPRIN expression was investigated with immunohistochemistry in 103 uterine smooth muscle tumors, which included 19 usual leiomyomas, 52 leiomyoma variants, and 32 LMS. They were evaluated on the basis of staining extent, intensity, and also their combined score, and the groups were compared. EMMPRIN expression was present in 3 of 19 (15.7%) usual leiomyomas, 23 of 52 (44.3%) leiomyoma variants, and 28 of 32 (87.5%) LMS. There were statistically significant differences in staining extent and intensity, and also for their combined scores, between the LMS and benign groups. Although uterine smooth muscle tumors are usually diagnosed easily with conventional diagnostic criteria, the differentiation of LMS from some variants of leiomyoma can be challenging based soley on morphology. EMMPRIN may be a valuable immunohistochemical marker for differentiating LMS from benign smooth muscle tumors in problematic cases.

Effect of the passive recovery period on the lactate minimum speed in sprinters and endurance runners.

PubMed

Denadai, B S; Higino, W P

2004-12-01

The objective of this study was to verify the effect of the passive recovery time following a supramaximal sprint exercise and the incremental exercise test on the lactate minimum speed (LMS). Thirteen sprinters and 12 endurance runners performed the following tests: (1) a maximal 500 m sprint followed by a passive recovery to determine the time to reach the peak blood lactate concentration; (2) after the maximal 500 m sprint, the athletes rested eight mins, and then performed 6 x 800 m incremental test, in order to determine the speed corresponding to the lower blood lactate concentration (LMS1) and; (3) identical procedures of the LMS1, differing only in the passive rest time, that was performed in accordance with the time to peak lactate (LMS2). The time (min) to reach the peak blood lactate concentration was significantly higher in the sprinters (12.76 +/- 2.83) than in the endurance runners (10.25 +/- 3.01). There was no significant difference between LMS 1 and LMS2, for both endurance (285.7 +/- 19.9; 283.9 +/- 17.8 m/min; r = 0.96) and sprint runners (238.0 +/- 14.1; 239.4 +/- 13.9 m/min; r = 0.93), respectively. We can conclude that the LMS is not influenced by a passive recovery period longer than eight mins (adjusted according with the time to peak blood lactate), although blood lactate concentration may differ at this speed. The predominant type of training (aerobic or anaerobic) of the athletes does not seem to influence the phenomenon previously described.

The use of herbs by california midwives.

PubMed

Dennehy, Cathi; Tsourounis, Candy; Bui, Lindsey; King, Tekoa L

2010-01-01

To characterize herbal product use (prevalence, types, indications) among Certified Nurse Midwives/Certified Midwives (CNMs/CMs) and Licensed Midwives (LMs) practicing in the state of California and to describe formal education related to herbal products received by midwives during midwifery education. Cross-sectional survey/California/Practicing midwives. A list of LMs and CNMs/CMs practicing in California was obtained through the California Medical Board (CMB) and the American College of Nurse Midwives (ACNM), respectively. The survey was mailed to 343 CNMs/CMs (one third of the ACNM mailing list) and 157 LMs (the complete CMB mailing list). Of the 500 surveys mailed, 40 were undeliverable, 146 were returned, and 7 were excluded (30% response rate). Of the 139 completed surveys, 58/102 (57%) of CNMs/CMs and 35/37 (95%) of LMs used herbs, and LMs were more comfortable than CNMs/CMs in recommending herbs to their patients. A majority of LMs had >20 hours of midwifery education on herbs whereas a majority of CNMs/CMs received 0 to 5 hours. Some CNMs/CMs indicated that their practice site limited their ability to use herbs. Common conditions in which LMs and CNMs/CMs used herbs were nausea/vomiting (86% vs. 83%), labor induction (89% vs. 58%), and lactation (86% vs. 65%). Specific herbs for all indications are described. Licensed midwives were more likely than CNMs/CMs to use herbs in clinical practice. This trend was likely a reflection of the amount of education devoted to herbs as well as herbal use limitations that may be encountered in institutional facilities. © 2010 AWHONN, the Association of Women's Health, Obstetric and Neonatal Nurses.

Mill Designed Bio bleaching Technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Institute of Paper Science Technology

2004-01-30

A key finding of this research program was that Laccase Mediator Systems (LMS) treatments on high-kappa kraft could be successfully accomplished providing substantial delignification (i.e., > 50%) without detrimental impact on viscosity and significantly improved yield properties. The efficiency of the LMS was evident since most of the lignin from the pulp was removed in less than one hour at 45 degrees C. Of the mediators investigated, violuric acid was the most effective vis-a-vis delignification. A comparative study between oxygen delignification and violuric acid revealed that under relatively mild conditions, a single or a double LMS{sub VA} treatment is comparablemore » to a single or a double O stage. Of great notability was the retention of end viscosity of LMS{sub VA} treated pulps with respect to the end viscosity of oxygen treated pulps. These pulps could then be bleached to full brightness values employing conventional ECF bleaching technologies and the final pulp physical properties were equal and/or better than those bleached in a conventional ECF manner employing an aggressively O or OO stage initially. Spectral analyses of residual lignins isolated after LMS treated high-kappa kraft pulps revealed that similar to HBT, VA and NHA preferentially attack phenolic lignin moieties. In addition, a substantial decrease in aliphatic hydroxyl groups was also noted, suggesting side chain oxidation. In all cases, an increase in carboxylic acid was observed. Of notable importance was the different selectivity of NHA, VA and HBT towards lignin functional groups, despite the common N-OH moiety. C-5 condensed phenolic lignin groups were overall resistant to an LMS{sub NHA, HBT} treatments but to a lesser extent to an LMS{sub VA}. The inactiveness of these condensed lignin moieties was not observed when low-kappa kraft pulps were biobleached, suggesting that the LMS chemistry is influenced by the extent of delignification. We have also demonstrated that the current generation of laccase has a broad spectrum of operating parameters. Nonetheless, the development of future genetically engineered laccases with enhanced temperature, pH and redox potentials will dramatically improve the overall process. A second challenge for LMS bleaching technologies is the need to develop effective, catalytic mediators. From the literature we already know this is feasible since ABTS and some inorganic mediators are catalytic. Unfortunately, the mediators that exhibit catalytic properties do not exhibit significant delignification properties and this is a challenge for future research studies. Potential short-term mill application of laccase has been recently reported by Felby132 and Chandra133 as they have demonstrated that the physical properties of linerboard can be improved when exposed to laccase without a chemical mediator. In addition, xxx has shown that the addition of laccase to the whitewater of the paper machine has several benefits for the removal of colloidal materials. Finally, this research program has presented important features on the delignification chemistry of LMS{sub NHA} and LMS{sub VA} that, in the opinion of the author, are momentous contributions to the overall LMS chemistry/biochemistry knowledge base which will continue to have future benefits.« less

Acute total left main stem occlusion treated with emergency percutaneous coronary intervention

PubMed Central

Mozid, A M; Sritharan, K; Clesham, G J

2010-01-01

Acute total occlusion of the left main stem (LMS) is a rare cause of myocardial infarction but carries a high risk of morbidity and mortality including presentation as sudden death. We describe the case of a 68-year-old woman who presented acutely with chest pain and ST segment elevation in lead aVR on her ECG suggestive of possible LMS occlusion. Emergency coronary angiography confirmed acute total LMS occlusion as well as an anomalous dominant right coronary artery. The patient underwent emergency percutaneous coronary intervention of the LMS with a good angiographic result and resolution of her symptoms. The patient was treated for acute left ventricular failure but made a gradual recovery and was discharged home 7 days after admission.

Paravertebral foramen screw fixation for posterior cervical spine fusion: biomechanical study and description of a novel technique.

PubMed

Maki, Satoshi; Aramomi, Masaaki; Matsuura, Yusuke; Furuya, Takeo; Ota, Mitsutoshi; Iijima, Yasushi; Saito, Junya; Suzuki, Takane; Mannoji, Chikato; Takahashi, Kazuhisa; Yamazaki, Masashi; Koda, Masao

2017-10-01

OBJECTIVE Fusion surgery with instrumentation is a widely accepted treatment for cervical spine pathologies. The authors propose a novel technique for subaxial cervical fusion surgery using paravertebral foramen screws (PVFS). The authors consider that PVFS have equal or greater biomechanical strength than lateral mass screws (LMS). The authors' goals of this study were to conduct a biomechanical study of PVFS, to investigate the suitability of PVFS as salvage fixation for failed LMS, and to describe this novel technique. METHODS The authors harvested 24 human cervical spine vertebrae (C3-6) from 6 fresh-frozen cadaver specimens from donors whose mean age was 84.3 ± 10.4 years at death. For each vertebra, one side was chosen randomly for PVFS and the other for LMS. For PVFS, a 3.2-mm drill with a stopper was advanced under lateral fluoroscopic imaging. The drill stopper was set to 12 mm, which was considered sufficiently short not to breach the transverse foramen. The drill was directed from 20° to 25° medially so that the screw could purchase the relatively hard cancellous bone around the entry zone of the pedicle. The hole was tapped and a 4.5-mm-diameter × 12-mm screw was inserted. For LMS, 3.5-mm-diameter × 14-mm screws were inserted into the lateral mass of C3-6. The pullout strength of each screw was measured. After pullout testing of LMS, a drill was inserted into the screw hole and the superior cortex of the lateral mass was pried to cause a fracture through the screw hole, simulating intraoperative fracture of the lateral mass. After the procedure, PVFS for salvage (sPVFS) were inserted on the same side and pullout strength was measured. RESULTS The CT scans obtained after screw insertion revealed no sign of pedicle breaching, violation of the transverse foramen, or fracture of the lateral mass. A total of 69 screws were tested (23 PVFS, 23 LMS, and 23 sPVFS). One vertebra was not used because of a fracture that occurred while the specimen was prepared. The mean bone mineral density of the specimens was 0.29 ± 0.10 g/cm 3 . The mean pullout strength was 234 ± 114 N for PVFS, 158 ± 91 N for LMS, and 195 ± 125 N for sPVFS. The pullout strength for PVFS tended to be greater than that for LMS. However, the difference was not quite significant (p = 0.06). CONCLUSIONS The authors introduce a novel fixation technique for the subaxial cervical spine. This study suggests that PVFS tend to provide stronger fixation than LMS for initial applications and fixation equal to LMS for salvage applications. If placement of LMS fails, PVFS can serve as a salvage fixation technique.

Late Cenozoic thrusting of major faults along the central segment of Longmen Shan, eastern Tibet: Evidence from low-temperature thermochronology

NASA Astrophysics Data System (ADS)

Tan, Xi-Bin; Xu, Xi-Wei; Lee, Yuan-Hsi; Lu, Ren-Qi; Liu, Yiduo; Xu, Chong; Li, Kang; Yu, Gui-Hua; Kang, Wen-Jun

2017-08-01

The Cenozoic orogenic process of the Longmen Shan (LMS) and the kinematics of major faults along the LMS are crucial for understanding the growth history and mechanism of the eastern Tibetan Plateau. Three major faults, from west to east, are present in the central segment of the LMS: the Wenchuan-Maoxian Fault (WMF), the Beichuan-Yingxiu Fault (BYF), and the Jiangyou-Guanxian Fault (JGF). Previous researchers have placed great impetus on the Pengguan Massif, between the WMF and BYF. However, limited low-temperature thermochronology data coverage in other areas prevents us from fully delineating the tectonic history of the LMS. In this study, we collect 22 samples from vertical profiles in the Xuelongbao Massif and the range frontal area located at the hanging walls of the WMF and JGF respectively, and conduct apatite and zircon fission track analyses. New fission track data reveal that the Xuelongbao Massif has been undergoing rapid exhumation with an average rate of 0.7-0.9 mm/yr since 11 Ma, and the range frontal area began rapid exhumation at 7.5 Ma with total exhumation of 2.5-4.5 km. The exhumation histories indicate that the three major faults (WMF, BYF and JGF) in the central LMS are all reverse faults, and show a basinward in-sequence propagation from middle Miocene to present-day. Such a pattern further implies that upper crustal shortening is the primary driver for the LMS' uplift during the Late Cenozoic. Nevertheless, middle-lower crustal deformation is difficult to be constrained by the exhumation histories, and its contribution to LMS' uplift cannot be ruled out.

Radiotherapy-induced xerostomia, pre-clinical promise of LMS-611.

PubMed

Paterson, Claire; Caldwell, B; Porteous, S; McLean, A; Messow, C M; Thomson, M

2016-02-01

Radiotherapy-induced xerostomia (RIX) is the most common permanent side effect of radiotherapy (RT) to the head and neck (H&N). There is no effective topical treatment. LMS-611 is a mimetic of a natural lamellar body which prevents thick secretions like saliva from congesting organs. The primary objective of this study was to assess saliva properties before and during RT to the H&N. The secondary objectives were to re-assess saliva properties with the addition of LMS-611, measure inter-patient variability, correlate patient-reported symptoms with laboratory measurements and design subsequent first-in-human clinical trial of LMS-611. Patients with H&N cancer receiving RT as primary treatment were recruited. Patients completed the Groningen RIX (GRIX) questionnaire and provided saliva samples at baseline and weeks 2, 4 and 6 of RT. Saliva adhesiveness and viscosity were tested by measuring time taken to travel 5 cm down an inclined plane. Thirty patients were enrolled. The inclined plane test (IPT) results (s) were as follows: baseline 31.3, week 2 49.7, week 4 51.1 and week 6 55.7. Wide inter-patient variability was seen at baseline. GRIX scores increased as RT progressed. Spearman rank correlation coefficient of inclined plane tests with GRIX scores was -0.06 at baseline, 0.25 at week 2, 0.12 at week 4 and 0.08 at week 6. LMS-611 concentrations of 10 and 20 mg/ml significantly reduced IPT times on saliva samples. Saliva becomes more visco-adhesive and RIX worsens as RT progresses. There is little correlation between objective and subjective measures of RIX. The addition of LMS-611 to thick, sticky saliva restores its fluidity ex vivo. This warrants in vivo analysis of the effect of LMS-611 upon RIX.

Picibanil (OK-432) in the treatment of head and neck lymphangiomas in children

PubMed Central

Rebuffini, Elena; Zuccarino, Luca; Grecchi, Emma; Carinci, Francesco; Merulla, Vittorio Emanuele

2012-01-01

Background: Picibanil (OK-432) is a lyophilized mixture of group A Streptococcus pyogenes with antineoplastic activity. Because of its capacity to produce a selective fibrosis of lymphangiomas (LMs), it has been approved by Japanese administration in 1995 for the treatment of LMs. Materials and Methods: We treated 15 children (age range: 6-60 months) affected by head and neck macrocystic LMs with intracystic injections (single dose of 0.2 mL) of Picibanil (1-3 injections). Results: Complete disappearance of the lesion was noticed in eight (53.33%) cases, a marked (>50%) reduction of LMs was found five (33.33%) cases, while a moderate (<50%) response was recorded in two (13.33%) cases. Picibanil side effects included fever, local inflammation, and transitory increase of blood platelets’ concentration; a single case of anemia was resolved with concentrated red blood cells transfusion. Conclusions: Intracystic injection of Picibanil is an effective and safe treatment for macrocystic LMs in pediatric patients and may represent the treatment of choice in such cases, especially where surgical excision is associated with the risk of functional/cosmetic side effects. PMID:23814582

Picibanil (OK-432) in the treatment of head and neck lymphangiomas in children.

PubMed

Rebuffini, Elena; Zuccarino, Luca; Grecchi, Emma; Carinci, Francesco; Merulla, Vittorio Emanuele

2012-12-01

Picibanil (OK-432) is a lyophilized mixture of group A Streptococcus pyogenes with antineoplastic activity. Because of its capacity to produce a selective fibrosis of lymphangiomas (LMs), it has been approved by Japanese administration in 1995 for the treatment of LMs. We treated 15 children (age range: 6-60 months) affected by head and neck macrocystic LMs with intracystic injections (single dose of 0.2 mL) of Picibanil (1-3 injections). Complete disappearance of the lesion was noticed in eight (53.33%) cases, a marked (>50%) reduction of LMs was found five (33.33%) cases, while a moderate (<50%) response was recorded in two (13.33%) cases. Picibanil side effects included fever, local inflammation, and transitory increase of blood platelets' concentration; a single case of anemia was resolved with concentrated red blood cells transfusion. Intracystic injection of Picibanil is an effective and safe treatment for macrocystic LMs in pediatric patients and may represent the treatment of choice in such cases, especially where surgical excision is associated with the risk of functional/cosmetic side effects.

Development of an improved MATLAB GUI for the prediction of coefficients of restitution, and integration into LMS.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baca, Renee Nicole; Congdon, Michael L.; Brake, Matthew Robert

In 2012, a Matlab GUI for the prediction of the coefficient of restitution was developed in order to enable the formulation of more accurate Finite Element Analysis (FEA) models of components. This report details the development of a new Rebound Dynamics GUI, and how it differs from the previously developed program. The new GUI includes several new features, such as source and citation documentation for the material database, as well as a multiple materials impact modeler for use with LMS Virtual.Lab Motion (LMS VLM), and a rigid body dynamics modeling software. The Rebound Dynamics GUI has been designed to workmore » with LMS VLM to enable straightforward incorporation of velocity-dependent coefficients of restitution in rigid body dynamics simulations.« less

OPUS One: An Intelligent Adaptive Learning Environment Using Artificial Intelligence Support

NASA Astrophysics Data System (ADS)

Pedrazzoli, Attilio

2010-06-01

AI based Tutoring and Learning Path Adaptation are well known concepts in e-Learning scenarios today and increasingly applied in modern learning environments. In order to gain more flexibility and to enhance existing e-learning platforms, the OPUS One LMS Extension package will enable a generic Intelligent Tutored Adaptive Learning Environment, based on a holistic Multidimensional Instructional Design Model (PENTHA ID Model), allowing AI based tutoring and adaptation functionality to existing Web-based e-learning systems. Relying on "real time" adapted profiles, it allows content- / course authors to apply a dynamic course design, supporting tutored, collaborative sessions and activities, as suggested by modern pedagogy. The concept presented combines a personalized level of surveillance, learning activity- and learning path adaptation suggestions to ensure the students learning motivation and learning success. The OPUS One concept allows to implement an advanced tutoring approach combining "expert based" e-tutoring with the more "personal" human tutoring function. It supplies the "Human Tutor" with precise, extended course activity data and "adaptation" suggestions based on predefined subject matter rules. The concept architecture is modular allowing a personalized platform configuration.

OH/H2O Detection Capability Evaluation on Chang'e-5 Lunar Mineralogical Spectrometer (LMS)

NASA Astrophysics Data System (ADS)

Liu, Bin; Ren, Xin; Liu, Jianjun; Li, Chunlai; Mu, Lingli; Deng, Liyan

2016-10-01

The Chang'e-5 (CE-5) lunar sample return mission is scheduled to launch in 2017 to bring back lunar regolith and drill samples. The Chang'e-5 Lunar Mineralogical Spectrometer (LMS), as one of the three sets of scientific payload installed on the lander, is used to collect in-situ spectrum and analyze the mineralogical composition of the samplingsite. It can also help to select the sampling site, and to compare the measured laboratory spectrum of returned sample with in-situ data. LMS employs acousto-optic tunable filters (AOTFs) and is composed of a VIS/NIR module (0.48μm-1.45μm) and an IR module (1.4μm -3.2μm). It has spectral resolution ranging from 3 to 25 nm, with a field of view (FOV) of 4.24°×4.24°. Unlike Chang'e-3 VIS/NIR Imaging Spectrometer (VNIS), the spectral coverage of LMS is extended from 2.4μm to 3.2μm, which has capability to identify H2O/OH absorption features around 2.7μm. An aluminum plate and an Infragold plate are fixed in the dust cover, being used as calibration targets in the VIS/NIR and IR spectral range respectively when the dust cover is open. Before launch, a ground verification test of LMS needs to be conducted in order to: 1) test and verify the detection capability of LMS through evaluation on the quality of image and spectral data collected for the simulated lunar samples; and 2) evaluate the accuracy of data processing methods by the simulation of instrument working on the moon. The ground verification test will be conducted both in the lab and field. The spectra of simulated lunar regolith/mineral samples will be collected simultaneously by the LMS and two calibrated spectrometers: a FTIR spectrometer (Model 102F) and an ASD FieldSpec 4 Hi-Res spectrometer. In this study, the results of the LMS ground verification test will be reported, and OH/H2O Detection Capability will be evaluated especially.

Both Baseline and Change in Lower Limb Muscle Strength in Younger Women Are Independent Predictors of Balance in Middle Age: A 12-Year Population-Based Prospective Study.

PubMed

Wu, Feitong; Callisaya, Michele; Wills, Karen; Laslett, Laura L; Jones, Graeme; Winzenberg, Tania

2017-06-01

Poor balance is a risk factor for falls and fracture in older adults, but little is known about modifiable factors affecting balance in younger women. This study aimed to examine whether lower limb muscle strength (LMS) in young women and changes in LMS are independent predictors of balance in middle age. This was an observational 10-year follow-up of 470 women aged 25 to 44 years at baseline who had previously participated in a 2-year population-based randomized controlled trial of osteoporosis education interventions. Linear regression was used to examine the association between baseline LMS (by dynamometer) and change in LMS over 12 years with balance at 12 years (timed up and go test [TUG], step test [ST], functional reach test [FRT], and lateral reach test [LRT]). LMS declined by a mean of 17.3 kg over 12 years. After adjustment for potential confounders, baseline and change in LMS were independently beneficially associated with TUG (β = -0.008 sec/kg, 95% confidence interval [CI] -0.01 to -0.006, and β = -0.006 sec/kg, 95% CI -0.009 to -0.003 for baseline and change, respectively), FRT (β = 0.057 cm/kg, 95% CI 0.030 to 0.084, and β = 0.071 cm/kg, 95% CI 0.042 to 0.101, respectively), and LRT (β = 0.030 cm/kg, 95% CI 0.012 to 0.049, and β = 0.022 cm/kg, 95% CI 0.002 to 0.043, respectively) 12 years later. There was an association between baseline LMS and ST (β = 0.044 steps/kg, 95% CI 0.022 to 0.067) but not between change in LMS and ST. Among young women, greater LMS at baseline and slower decline over time are both associated with better balance in midlife. Analogous to the contributions of peak bone mass and bone loss to fracture risk in older adults, this suggests that both improvement of muscle strength in younger age and prevention of age-related loss of muscle strength could be potentially useful strategies to improve balance and reduce falls in later life. © 2017 American Society for Bone and Mineral Research. © 2017 American Society for Bone and Mineral Research.

Space-Time Joint Interference Cancellation Using Fuzzy-Inference-Based Adaptive Filtering Techniques in Frequency-Selective Multipath Channels

NASA Astrophysics Data System (ADS)

Hu, Chia-Chang; Lin, Hsuan-Yu; Chen, Yu-Fan; Wen, Jyh-Horng

2006-12-01

An adaptive minimum mean-square error (MMSE) array receiver based on the fuzzy-logic recursive least-squares (RLS) algorithm is developed for asynchronous DS-CDMA interference suppression in the presence of frequency-selective multipath fading. This receiver employs a fuzzy-logic control mechanism to perform the nonlinear mapping of the squared error and squared error variation, denoted by ([InlineEquation not available: see fulltext.],[InlineEquation not available: see fulltext.]), into a forgetting factor[InlineEquation not available: see fulltext.]. For the real-time applicability, a computationally efficient version of the proposed receiver is derived based on the least-mean-square (LMS) algorithm using the fuzzy-inference-controlled step-size[InlineEquation not available: see fulltext.]. This receiver is capable of providing both fast convergence/tracking capability as well as small steady-state misadjustment as compared with conventional LMS- and RLS-based MMSE DS-CDMA receivers. Simulations show that the fuzzy-logic LMS and RLS algorithms outperform, respectively, other variable step-size LMS (VSS-LMS) and variable forgetting factor RLS (VFF-RLS) algorithms at least 3 dB and 1.5 dB in bit-error-rate (BER) for multipath fading channels.

Health professional learner attitudes and use of digital learning resources.

PubMed

Maloney, Stephen; Chamberlain, Michael; Morrison, Shane; Kotsanas, George; Keating, Jennifer L; Ilic, Dragan

2013-01-16

Web-based digital repositories allow educational resources to be accessed efficiently and conveniently from diverse geographic locations, hold a variety of resource formats, enable interactive learning, and facilitate targeted access for the user. Unlike some other learning management systems (LMS), resources can be retrieved through search engines and meta-tagged labels, and content can be streamed, which is particularly useful for multimedia resources. The aim of this study was to examine usage and user experiences of an online learning repository (Physeek) in a population of physiotherapy students. The secondary aim of this project was to examine how students prefer to access resources and which resources they find most helpful. The following data were examined using an audit of the repository server: (1) number of online resources accessed per day in 2010, (2) number of each type of resource accessed, (3) number of resources accessed during business hours (9 am to 5 pm) and outside business hours (years 1-4), (4) session length of each log-on (years 1-4), and (5) video quality (bit rate) of each video accessed. An online questionnaire and 3 focus groups assessed student feedback and self-reported experiences of Physeek. Students preferred the support provided by Physeek to other sources of educational material primarily because of its efficiency. Peak usage commonly occurred at times of increased academic need (ie, examination times). Students perceived online repositories as a potential tool to support lifelong learning and health care delivery. The results of this study indicate that today's health professional students welcome the benefits of online learning resources because of their convenience and usability. This represents a transition away from traditional learning styles and toward technological learning support and may indicate a growing link between social immersions in Internet-based connections and learning styles. The true potential for Web-based resources to support student learning is as yet unknown.

Health Professional Learner Attitudes and Use of Digital Learning Resources

PubMed Central

Chamberlain, Michael; Morrison, Shane; Kotsanas, George; Keating, Jennifer L; Ilic, Dragan

2013-01-01

Background Web-based digital repositories allow educational resources to be accessed efficiently and conveniently from diverse geographic locations, hold a variety of resource formats, enable interactive learning, and facilitate targeted access for the user. Unlike some other learning management systems (LMS), resources can be retrieved through search engines and meta-tagged labels, and content can be streamed, which is particularly useful for multimedia resources. Objective The aim of this study was to examine usage and user experiences of an online learning repository (Physeek) in a population of physiotherapy students. The secondary aim of this project was to examine how students prefer to access resources and which resources they find most helpful. Methods The following data were examined using an audit of the repository server: (1) number of online resources accessed per day in 2010, (2) number of each type of resource accessed, (3) number of resources accessed during business hours (9 am to 5 pm) and outside business hours (years 1-4), (4) session length of each log-on (years 1-4), and (5) video quality (bit rate) of each video accessed. An online questionnaire and 3 focus groups assessed student feedback and self-reported experiences of Physeek. Results Students preferred the support provided by Physeek to other sources of educational material primarily because of its efficiency. Peak usage commonly occurred at times of increased academic need (ie, examination times). Students perceived online repositories as a potential tool to support lifelong learning and health care delivery. Conclusions The results of this study indicate that today’s health professional students welcome the benefits of online learning resources because of their convenience and usability. This represents a transition away from traditional learning styles and toward technological learning support and may indicate a growing link between social immersions in Internet-based connections and learning styles. The true potential for Web-based resources to support student learning is as yet unknown. PMID:23324800

Outcome of inferior vena cava and noncaval venous leiomyosarcomas.

PubMed

Illuminati, Giulio; Pizzardi, Giulia; Calio', Francesco; Pacilè, Maria Antonietta; Masci, Federica; Vietri, Francesco

2016-02-01

Leiomyosarcoma (LMS) is a rare tumor arising from the smooth muscle cells of arteries and veins. LMS may affect both the inferior vena cava (IVC) and non-IVC veins. Because of its rarity, the experience with the outcome of the disease originating from the IVC compared with that with non-IVC offspring is overall limited. In this study, we compared the clinical features and outcomes after operative resection of IVC and non-IVC LMS to detect possible significant differences that could affect treatment and prognosis. Twenty-seven patients undergoing operative resection of a venous LMS at a single tertiary care center and one secondary care hospital were reviewed retrospectively and divided into 2 groups: IVC-LMS (Group A, n = 18) and non-IVC LMS (Group B, n = 9). As primary end points, postoperative mortality and morbidity, disease-specific survival and, if applicable, patency of venous reconstruction were considered. Bivariate differences were compared with the χ(2) test. Disease-specific survival was expressed by a life-table analysis and compared using the log-rank test. No postoperative mortality was observed in either group. Postoperative morbidity was 28% in group A and 11% in group B (P = .33). The mean duration of follow-up was 60 months (range, 13-140). Disease-specific survival was 60% in group A and 75% in group B at 3 years (P = .48), and it was 54% in group A and 62% in group B at 5 years (P = .63). Seven grafts were occluded in group A (39%) and 1of 3 were occluded in group B (33%) (P = .85). IVC and non-IVC LMS exhibit similar outcomes in terms of postoperative course and survival. Operative resection associated with vascular reconstruction, if applicable, eventually followed by radiation and chemotherapy may be curative and is associated with good functional results. Copyright © 2016 Elsevier Inc. All rights reserved.

Evaluation of Local Media Surveillance for Improved Disease Recognition and Monitoring in Global Hotspot Regions

PubMed Central

Schwind, Jessica S.; Wolking, David J.; Brownstein, John S.; Mazet, Jonna A. K.; Smith, Woutrina A.

2014-01-01

Digital disease detection tools are technologically sophisticated, but dependent on digital information, which for many areas suffering from high disease burdens is simply not an option. In areas where news is often reported in local media with no digital counterpart, integration of local news information with digital surveillance systems, such as HealthMap (Boston Children’s Hospital), is critical. Little research has been published in regards to the specific contribution of local health-related articles to digital surveillance systems. In response, the USAID PREDICT project implemented a local media surveillance (LMS) pilot study in partner countries to monitor disease events reported in print media. This research assessed the potential of LMS to enhance digital surveillance reach in five low- and middle-income countries. Over 16 weeks, select surveillance system attributes of LMS, such as simplicity, flexibility, acceptability, timeliness, and stability were evaluated to identify strengths and weaknesses in the surveillance method. Findings revealed that LMS filled gaps in digital surveillance network coverage by contributing valuable localized information on disease events to the global HealthMap database. A total of 87 health events were reported through the LMS pilot in the 16-week monitoring period, including 71 unique reports not found by the HealthMap digital detection tool. Furthermore, HealthMap identified an additional 236 health events outside of LMS. It was also observed that belief in the importance of the project and proper source selection from the participants was crucial to the success of this method. The timely identification of disease outbreaks near points of emergence and the recognition of risk factors associated with disease occurrence continue to be important components of any comprehensive surveillance system for monitoring disease activity across populations. The LMS method, with its minimal resource commitment, could be one tool used to address the information gaps seen in global ‘hot spot’ regions. PMID:25333618

Crustal structure and deformation under the Longmenshan and its surroundings revealed by receiver function data

NASA Astrophysics Data System (ADS)

Sun, Ya; Liu, Jianxin; Zhou, Keping; Chen, Bo; Guo, Rongwen

2015-07-01

The convergence of India and Eurasia and the obstruction from the rigid Sichuan Basin cause the Longmenshan (LMS) to have the steepest topographic gradient at the eastern margin of the Tibetan Plateau. However, the mechanisms of surface uplift are still controversial. In this paper, we estimate the crustal structure and deformation under the LMS and its surroundings by analyzing a large amount of receiver function data recorded by regional seismic networks of the China Earthquake Administration. We apply a comprehensive splitting measurement technique on Ps conversion phase at the Moho (Moho Ps splitting) to calculate crustal anisotropy from azimuthal variations of receiver functions. Our results show that most of the seismic stations beneath the LMS area exhibit significant seismic anisotropy with the splitting time of 0.22-0.94 s and a fast polarization direction of NW-SE, while less or even no crustal anisotropy has been observed under the Sichuan Basin. Comparing the fast polarization directions of Moho Ps splitting with the indicators of lithospheric deformation (such as shear wave splitting, absolute plate motion, and global positioning system) imply a consistent tendency of deformation between the lower crust and upper mantle, but decoupling deformation in the crust beneath the LMS area. We further compare Moho Ps splitting time to that estimated from previous SKS splitting, indicating that crustal anisotropy is an important source of the SKS splitting time in this study area. In addition, a thick crust (>50 km) with high Vp/Vs values (1.74-1.86) is also observed using the H-κ stacking method. These seismic observations are consistent with the scenario that the LMS area has been built by the lower crustal flow. Combined with the seismic reflection/refraction profile and geology studies, we further suggest that the lower crustal flow may extrude upward into the upper crust along the steeply dipping strike faults under the LMS area, resulting in the surface uplift of the LMS.

Light-driven liquid metal nanotransformers for biomedical theranostics

NASA Astrophysics Data System (ADS)

Chechetka, Svetlana A.; Yu, Yue; Zhen, Xu; Pramanik, Manojit; Pu, Kanyi; Miyako, Eijiro

2017-05-01

Room temperature liquid metals (LMs) represent a class of emerging multifunctional materials with attractive novel properties. Here, we show that photopolymerized LMs present a unique nanoscale capsule structure characterized by high water dispersibility and low toxicity. We also demonstrate that the LM nanocapsule generates heat and reactive oxygen species under biologically neutral near-infrared (NIR) laser irradiation. Concomitantly, NIR laser exposure induces a transformation in LM shape, destruction of the nanocapsules, contactless controlled release of the loaded drugs, optical manipulations of a microfluidic blood vessel model and spatiotemporal targeted marking for X-ray-enhanced imaging in biological organs and a living mouse. By exploiting the physicochemical properties of LMs, we achieve effective cancer cell elimination and control of intercellular calcium ion flux. In addition, LMs display a photoacoustic effect in living animals during NIR laser treatment, making this system a powerful tool for bioimaging.

Light-driven liquid metal nanotransformers for biomedical theranostics

PubMed Central

Chechetka, Svetlana A.; Yu, Yue; Zhen, Xu; Pramanik, Manojit; Pu, Kanyi; Miyako, Eijiro

2017-01-01

Room temperature liquid metals (LMs) represent a class of emerging multifunctional materials with attractive novel properties. Here, we show that photopolymerized LMs present a unique nanoscale capsule structure characterized by high water dispersibility and low toxicity. We also demonstrate that the LM nanocapsule generates heat and reactive oxygen species under biologically neutral near-infrared (NIR) laser irradiation. Concomitantly, NIR laser exposure induces a transformation in LM shape, destruction of the nanocapsules, contactless controlled release of the loaded drugs, optical manipulations of a microfluidic blood vessel model and spatiotemporal targeted marking for X-ray-enhanced imaging in biological organs and a living mouse. By exploiting the physicochemical properties of LMs, we achieve effective cancer cell elimination and control of intercellular calcium ion flux. In addition, LMs display a photoacoustic effect in living animals during NIR laser treatment, making this system a powerful tool for bioimaging. PMID:28561016

Significant radiative impact of volcanic aerosol in the lowermost stratosphere

PubMed Central

Andersson, Sandra M.; Martinsson, Bengt G.; Vernier, Jean-Paul; Friberg, Johan; Brenninkmeijer, Carl A. M.; Hermann, Markus; van Velthoven, Peter F. J.; Zahn, Andreas

2015-01-01

Despite their potential to slow global warming, until recently, the radiative forcing associated with volcanic aerosols in the lowermost stratosphere (LMS) had not been considered. Here we study volcanic aerosol changes in the stratosphere using lidar measurements from the NASA CALIPSO satellite and aircraft measurements from the IAGOS-CARIBIC observatory. Between 2008 and 2012 volcanism frequently affected the Northern Hemisphere stratosphere aerosol loadings, whereas the Southern Hemisphere generally had loadings close to background conditions. We show that half of the global stratospheric aerosol optical depth following the Kasatochi, Sarychev and Nabro eruptions is attributable to LMS aerosol. On average, 30% of the global stratospheric aerosol optical depth originated in the LMS during the period 2008–2011. On the basis of the two independent, high-resolution measurement methods, we show that the LMS makes an important contribution to the overall volcanic forcing. PMID:26158244

[Epithelioid leiomyosarcoma of the stomach. Clinical experiences with a rare stomach tumor].

PubMed

Hauser, H; Steindorfer, P; Mischinger, H J; Thalhammer, M; Kronberger, L; Rosanelli, G; Lax, S F

1995-01-01

Gastric epithelioid leiomyosarcoma (epLMS), which generally occurs in mid- or late adult life, is a rare smooth muscle tumor of the stomach. Out of 25 soft tissue tumors of the stomach operated at the Department of Surgery, University of Graz, two epLMS were diagnosed. This paper presents the case of a 67-year-old male with an epLMS in the corpus and of a 80-year-old female with an epLMS in the fundus of the stomach. The tumors were not diagnosed by gastroscopy; they were localized by sonography and CT-scan. In both cases the tumor was completely removed surgically, using a TA 90 4.8 mm respectively a TA 55 4.8 mm stapler. Diagnosis was reached by histological and immunohistochemical examination of the tumor tissue. Surgical excision with wide tumor-free resection margins is the therapy of choice in this tumor group.

[Comparison among various software for LMS growth curve fitting methods].

PubMed

Han, Lin; Wu, Wenhong; Wei, Qiuxia

2015-03-01

To explore the methods to realize the growth curve fitting of coefficients of skewness-median-coefficient of variation (LMS) using different software, and to optimize growth curve statistical method for grass-root child and adolescent staffs. Regular physical examination data of head circumference for normal infants aging 3, 6, 9 and 12 months in Baotou City were analyzed. Statistical software such as SAS, R, STATA and SPSS were used to fit the LMS growth curve and the results were evaluated upon the user 's convenience, study circle, user interface, results display forms, software update and maintenance and so on. Growth curve fitting results showed the same calculation outcome and each of statistical software had its own advantages and disadvantages. With all the evaluation aspects in consideration, R software excelled others in LMS growth curve fitting. R software have the advantage over other software in grass roots child and adolescent staff.

VLSI implementation of a new LMS-based algorithm for noise removal in ECG signal

NASA Astrophysics Data System (ADS)

Satheeskumaran, S.; Sabrigiriraj, M.

2016-06-01

Least mean square (LMS)-based adaptive filters are widely deployed for removing artefacts in electrocardiogram (ECG) due to less number of computations. But they posses high mean square error (MSE) under noisy environment. The transform domain variable step-size LMS algorithm reduces the MSE at the cost of computational complexity. In this paper, a variable step-size delayed LMS adaptive filter is used to remove the artefacts from the ECG signal for improved feature extraction. The dedicated digital Signal processors provide fast processing, but they are not flexible. By using field programmable gate arrays, the pipelined architectures can be used to enhance the system performance. The pipelined architecture can enhance the operation efficiency of the adaptive filter and save the power consumption. This technique provides high signal-to-noise ratio and low MSE with reduced computational complexity; hence, it is a useful method for monitoring patients with heart-related problem.

Preliminary Guidelines for Installation Product Line Land Management Suite (LMS) Product Developers

DTIC Science & Technology

2005-01-01

land use patterns might call a storm simulation model available as a CDF service to evaluate the ability of the pattern to maintain water quality ...Analysis GIS data Server Internal DIAS objects External DIAS objects External CDF services Fort Future DIAS Model GUI Figure 10. A Fort Future DIAS...31 iv ERDC/CERL TR-05-1 Are Programs that Analyze Data Being Developed as CDF Services

Langerian mindfulness, quality of life and psychological symptoms in a sample of Italian students.

PubMed

Pagnini, Francesco; Bercovitz, Katherine E; Phillips, Deborah

2018-02-06

Noticing new things, accepting the continuously changing nature of circumstances, and flexibly shifting perspectives in concert with changing contexts constitute the essential features of Langerian mindfulness. This contrasts with a "mindless" approach in which one remains fixed in a singular mindset and is closed off to new possibilities. Despite potentially important clinical applications for this construct, few studies have explored them. The instrument developed to measure Langerian mindfulness is the Langer Mindfulness Scale (LMS), although this tool has been limited primarily to English-speaking populations. The study aimed to test LMS validity in the Italian language and to analyze the relationships between Langerian mindfulness and well-being. We translated the LMS into Italian, analyzed its factor structure, and investigated the correlation between mindfulness and quality of life and psychological well-being in a sample of 248 Italian students (88.7% females, mean age 20.05). A confirmatory factor analysis confirmed the tri-dimensional structure of the English LMS in the Italian version. The primary analysis found a significant negative correlation between mindfulness and psychological symptoms including obsessive-compulsive tendencies, depression, anxiety, and paranoid ideation. There was also a positive correlation between mindfulness and reports of quality of life. The Italian LMS appears reliable and it shows relevant correlations with well-being.

Application of least mean square algorithm to suppression of maglev track-induced self-excited vibration

NASA Astrophysics Data System (ADS)

Zhou, D. F.; Li, J.; Hansen, C. H.

2011-11-01

Track-induced self-excited vibration is commonly encountered in EMS (electromagnetic suspension) maglev systems, and a solution to this problem is important in enabling the commercial widespread implementation of maglev systems. Here, the coupled model of the steel track and the magnetic levitation system is developed, and its stability is investigated using the Nyquist criterion. The harmonic balance method is employed to investigate the stability and amplitude of the self-excited vibration, which provides an explanation of the phenomenon that track-induced self-excited vibration generally occurs at a specified amplitude and frequency. To eliminate the self-excited vibration, an improved LMS (Least Mean Square) cancellation algorithm with phase correction (C-LMS) is employed. The harmonic balance analysis shows that the C-LMS cancellation algorithm can completely suppress the self-excited vibration. To achieve adaptive cancellation, a frequency estimator similar to the tuner of a TV receiver is employed to provide the C-LMS algorithm with a roughly estimated reference frequency. Numerical simulation and experiments undertaken on the CMS-04 vehicle show that the proposed adaptive C-LMS algorithm can effectively eliminate the self-excited vibration over a wide frequency range, and that the robustness of the algorithm suggests excellent potential for application to EMS maglev systems.

Floral volatile alleles can contribute to pollinator-mediated reproductive isolation in monkeyflowers (Mimulus)

PubMed Central

Byers, Kelsey J.R.P.; Vela, James P.; Peng, Foen; Riffell, Jeffrey A.; Bradshaw, H.D.

2014-01-01

Summary Pollinator-mediated reproductive isolation is a major factor in driving the diversification of flowering plants. Studies of floral traits involved in reproductive isolation have focused nearly exclusively on visual signals, such as flower color. The role of less obvious signals, such as floral scent, has been studied only recently. In particular, the genetics of floral volatiles involved in mediating differential pollinator visitation remains unknown. The bumblebee-pollinated Mimulus lewisii and hummingbird-pollinated M. cardinalis are a model system for studying reproductive isolation via pollinator preference. We have shown that these two species differ in three floral terpenoid volatiles - D-limonene, β-myrcene, and E-β-ocimene - that are attractive to bumblebee pollinators. By genetic mapping and in vitro enzyme activity analysis we demonstrate that these interspecific differences are consistent with allelic variation at two loci – LIMONENE-MYRCENE SYNTHASE (LMS) and OCIMENE SYNTHASE (OS). M. lewisii LMS (MlLMS) and OS (MlOS) are expressed most strongly in floral tissue in the last stages of floral development. M. cardinalis LMS (McLMS) is weakly expressed and has a nonsense mutation in exon 3. M. cardinalis OS (McOS) is expressed similarly to MlOS, but the encoded McOS enzyme produces no E-β-ocimene. Recapitulating the M. cardinalis phenotype by reducing the expression of MlLMS by RNAi in transgenic M. lewisii produces no behavioral difference in pollinating bumblebees; however, reducing MlOS expression produces a 6% decrease in visitation. Allelic variation at the OCIMENE SYNTHASE locus likely contributes to differential pollinator visitation, and thus promotes reproductive isolation between M. lewisii and M. cardinalis. OCIMENE SYNTHASE joins a growing list of “speciation genes” (“barrier genes”) in flowering plants. PMID:25319242

Multimodal ultrasonographic assessment of leiomyosarcoma of the femoral vein in a patient misdiagnosed as having deep vein thrombosis: A case report.

PubMed

Zhang, Mei; Yan, Feng; Huang, Bin; Wu, Zhoupeng; Wen, Xiaorong

2017-11-01

Primary leiomyosarcoma (LMS) of the vein is a rare tumor that arises from the smooth muscle cells of the vessel wall and has an extremely poor prognosis. This tumor can occur in vessels such as the inferior vena cava, great saphenous vein, femoral vein, iliac vein, popliteal vein, and renal vein; the inferior vena cava is the most common site. LMS of the femoral vein can result in edema and pain in the lower extremity; therefore, it is not easy to be differentiated from deep vein thrombosis (DVT). Moreover, virtually no studies have described the ultrasonographic features of LMS of the vein in detail. We present a case of a 55-year-old woman with LMS of the left femoral vein that was misdiagnosed as having deep vein thrombosis (DVT) on initial ultrasonographic examination. The patient began to experience edema and pain in her left leg seven months previously. She was diagnosed as having DVT on initial ultrasonographic examination, but the DVT treatment that she had received for 7 months failed to improve the status of her left lower limb. She subsequently underwent re-examination by means of a multimodal ultrasonographic imaging approach (regular B-mode imaging, color Doppler imaging, pulsed-wave Doppler imaging, contrast-enhanced ultrasonography), which confirmed a diagnosis of LMS. This patient was treated successfully with surgery. This case demonstrates that use of multiple ultrasonographic imaging techniques can be helpful to diagnose LMS accurately. Detection of vasculature in a dilated vein filled with a heterogeneous hypoechoic substance on ultrasonography is a sign of a tumor. The pitfall of misdiagnosing this tumor as DVT is a useful reminder.

Multimodal ultrasonographic assessment of leiomyosarcoma of the femoral vein in a patient misdiagnosed as having deep vein thrombosis

PubMed Central

Zhang, Mei; Yan, Feng; Huang, Bin; Wu, Zhoupeng; Wen, Xiaorong

2017-01-01

Abstract Rationale: Primary leiomyosarcoma (LMS) of the vein is a rare tumor that arises from the smooth muscle cells of the vessel wall and has an extremely poor prognosis. This tumor can occur in vessels such as the inferior vena cava, great saphenous vein, femoral vein, iliac vein, popliteal vein, and renal vein; the inferior vena cava is the most common site. LMS of the femoral vein can result in edema and pain in the lower extremity; therefore, it is not easy to be differentiated from deep vein thrombosis (DVT). Moreover, virtually no studies have described the ultrasonographic features of LMS of the vein in detail. Patient concerns: We present a case of a 55-year-old woman with LMS of the left femoral vein that was misdiagnosed as having deep vein thrombosis (DVT) on initial ultrasonographic examination. The patient began to experience edema and pain in her left leg seven months previously. She was diagnosed as having DVT on initial ultrasonographic examination, but the DVT treatment that she had received for 7 months failed to improve the status of her left lower limb. Diagnoses: She subsequently underwent re-examination by means of a multimodal ultrasonographic imaging approach (regular B-mode imaging, color Doppler imaging, pulsed-wave Doppler imaging, contrast-enhanced ultrasonography), which confirmed a diagnosis of LMS. Interventions: This patient was treated successfully with surgery. Outcomes: This case demonstrates that use of multiple ultrasonographic imaging techniques can be helpful to diagnose LMS accurately. Detection of vasculature in a dilated vein filled with a heterogeneous hypoechoic substance on ultrasonography is a sign of a tumor. Lessons: The pitfall of misdiagnosing this tumor as DVT is a useful reminder. PMID:29145269

Impact of Starting Point and Bicortical Purchase of C1 Lateral Mass Screws on Atlantoaxial Fusion: Meta-Analysis and Review of the Literature.

PubMed

Elliott, Robert E; Tanweer, Omar; Smith, Michael L; Frempong-Boadu, Anthony

2015-08-01

Structured review of literature and application of meta-analysis statistical techniques. Review published series describing clinical and radiographic outcomes of patients treated with C1 lateral mass screws (C1LMS), specifically analyzing the impact of starting point and bicortical purchase on successful atlantoaxial arthrodesis. Biomechanical studies suggest posterior arch screws and C1LMS with bicortical purchase are stronger than screws placed within the center of the lateral mass or those with unicortical purchase. Online databases were searched for English-language articles between 1994 and 2012 describing posterior atlantal instrumentation with C1LMS. Thirty-four studies describing 1247 patients having posterior atlantoaxial fusion with C1LMS met inclusion criteria. All studies provided class III evidence. Arthrodesis was quite successful regardless of technique (99.0% overall). Meta-analysis and multivariate regression analyses showed that neither posterior arch starting point nor bicortical screw purchase translated into a higher rate of successful arthrodesis. There were no complications from bicortical screw purchase. The Goel-Harms technique is a very safe and successful technique for achieving atlantoaxial fusion, regardless of minor variations in C1LMS technique. Although biomechanical studies suggest markedly increased rigidity of bicortical and posterior arch C1LMS, the significance of these findings may be minimal in the clinical setting of atlantoaxial fixation and fusion with modern techniques. The decision to use either technique must be made after careful review of the preoperative multiplanar computed tomography imaging, assessment of the unique anatomy of each patient, and the demands of the clinical scenario such as bone quality.

Teaching Labor Market Survey Methodology in Rehabilitation Counseling

ERIC Educational Resources Information Center

Barros-Bailey, Mary

2012-01-01

Labor Market Survey (LMS) and labor market analysis knowledge and methodologies are minimum competencies expected of rehabilitation counselors through credentialing and accreditation boards. However, LMS knowledge and methodology is an example of a contemporary oral tradition that is universally recognized in rehabilitation and disability services…

Investigation of best practices for maintenance of concrete bridge railings : [tech summary].

DOT National Transportation Integrated Search

2015-01-01

The development of bio lms on concrete structures has a negative impact on aesthetics as well as on the performance and integrity : of concrete structures. Bio lms develop and grow easily when the right conditions are present, such as high rela...

Interface Engineering Based on Liquid Metal for Compact-Layer-free, Fully Printable Mesoscopic Perovskite Solar Cells.

PubMed

Zhang, Yumin; Zhao, Jianhong; Zhang, Jin; Jiang, Xixi; Zhu, Zhongqi; Liu, Qingju

2018-05-09

A printing process for the fabrication of perovskite solar cells (PSCs) exhibits promising future application in the photovoltaic industry due to its low-cost and eco-friendly preparation. In mesoscopic carbon-based PSCs, however, compared to conventional ones, the hole-transport-layer-free PSCs often lead to inefficient hole extraction. Here, we used liquid metal (LM, Galinstan) as an interface modifier material in combination with a carbon electrode. Considering the high conductivity and room-temperature fluidity, it is found that LMs are superior in improving hole extraction and, more importantly, LMs tend to be reserved at the interface between ZrO 2 and carbon for enhancing the contact property. Correspondingly, the carrier transfer resistance was decreased at the carbon/perovskite interface. As optimized content, the triple mesoscopic PSCs based on mixed-cation perovskite with a power conversion efficiency of 13.51% was achieved, involving a 26% increase compared to those without LMs. This work opens new techniques for LMs in optoelectronics and printing.

Primary and secondary leiomyosarcoma of the oral and perioral region--clinicopathological and immunohistochemical analysis of a rare entity with a review of the literature.

PubMed

Schütz, Anja; Smeets, Ralf; Driemel, Oliver; Hakim, Samer George; Kosmehl, Hartwig; Hanken, Henning; Kolk, Andreas

2013-06-01

Leiomyosarcoma (LMS) rarely occurs in the head and neck region. These tumors present with a wide range of clinical features, so the diagnosis is predicated on conventional microscopic findings coupled with immunohistochemical analysis. Clinical and histologic data of 7 patients with LMS of the head and neck were recorded retrospectively. In addition to routine immunohistochemistry, staining for cell cycle regulator proteins p16 and p21 was performed. Five LMSs (4 intraoral, 1 dermal cheek) occurred primarily in the oral and perioral region. Two LMSs (parietal and sinonasal) were diagnosed as metastases originating from the uterus and pelvis. Treatment of the primary LMSs consisted of radical tumor resection with clear margins. Distant metastases from LMSs were irradiated or excised as palliative treatment. Three of 5 patients (60%) with primarily excised LMS developed recurrence after an average of 7 months, with lung metastases occurring after 17 months. In 1 patient, cervical lymph node metastases were detected after 10 months. Of all patients, 5 died after an average survival period of 2.4 years. The mean survival period of the 5 patients with primary LMS of the head and neck was 3.3 years. All tumors were positive for vimentin and α-smooth muscle actin, with 57% of tumors showing positive nuclear expression of p16 and 71% of p21. Lack of p16 nuclear expression was associated with a shorter mean survival time (1.3 vs 4.3 yr for p16 positivity). Lung and cervical lymph node metastases often occur in LMS of the head and neck. Presurgical staging, including gynecologic examination, whole-body computed tomography, and sometimes positron-emission or computed tomography, to rule out LMS metastasis is mandatory. Surgical resection of the tumor should be given top priority. Lack of p16 reactivity may have a prognostic value for LMS because it was related to a trend toward poorer survival. Copyright © 2013 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

Lower limb muscle strength is associated with poor balance in middle-aged women: linear and nonlinear analyses.

PubMed

Wu, F; Callisaya, M; Laslett, L L; Wills, K; Zhou, Y; Jones, G; Winzenberg, T

2016-07-01

This was the first study investigating both linear associations between lower limb muscle strength and balance in middle-aged women and the potential for thresholds for the associations. There was strong evidence that even in middle-aged women, poorer LMS was associated with reduced balance. However, no evidence was found for thresholds. Decline in balance begins in middle age, yet, the role of muscle strength in balance is rarely examined in this age group. We aimed to determine the association between lower limb muscle strength (LMS) and balance in middle-aged women and investigate whether cut-points of LMS exist that might identify women at risk of poorer balance. Cross-sectional analysis of 345 women aged 36-57 years was done. Associations between LMS and balance tests (timed up and go (TUG), step test (ST), functional reach test (FRT), and lateral reach test (LRT)) were assessed using linear regression. Nonlinear associations were explored using locally weighted regression smoothing (LOWESS) and potential cut-points identified using nonlinear least-squares estimation. Segmented regression was used to estimate associations above and below the identified cut-points. Weaker LMS was associated with poorer performance on the TUG (β -0.008 (95 % CI: -0.010, -0.005) second/kg), ST (β 0.031 (0.011, 0.051) step/kg), FRT (β 0.071 (0.047, 0.096) cm/kg), and LRT (β 0.028 (0.011, 0.044) cm/kg), independent of confounders. Potential nonlinear associations were evident from LOWESS results; significant cut-points of LMS were identified for all balance tests (29-50 kg). However, excepting ST, cut-points did not persist after excluding potentially influential data points. In middle-aged women, poorer LMS is associated with reduced balance. Therefore, improving muscle strength in middle-age may be a useful strategy to improve balance and reduce falls risk in later life. Middle-aged women with low muscle strength may be an effective target group for future randomized controlled trials. Australian New Zealand Clinical Trials Registry (ANZCTR) NCT00273260.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Dick; Tsosie, Bernadette

Groundwater samples were collected from monitoring wells at the Bluewater, New Mexico, Disposal Site to monitor groundwater contaminants as specified in the 1997 Long-Term Surveillance Plan for the DOE Bluewater (UMTRCA Title II) Disposal Site Near Grants, New Mexico (LTSP). Sampling and analyses were conducted as specified in the Sampling and Analysis Plan for U.S. Department of Energy Office of Legacy Management Sites (LMS/PRO/S04351, continually updated). A duplicate sample was collected from location 16(SG).

Engaging Students in a Large-Enrollment Physics Class Using an Academically Focused Social Media Platform

NASA Astrophysics Data System (ADS)

Gavrin, Andy; Lindell, Rebecca

2017-03-01

There are many reasons for an instructor to consider using social media, particularly in a large introductory course. Improved communications can lessen the sense of isolation some students feel in large classes, and students may be more likely to respond to faculty announce-ments in a form that is familiar and comfortable. Furthermore, many students currently establish social media sites for their classes, without the knowledge or participation of their instructors. Such "shadow" sites can be useful, but they can also become distributors of misinformation, or venues for inappropriate or disruptive discussions. CourseNetworking (CN) is a social media platform designed for the academic environment. It combines many features common among learning management systems (LMS's) with an interface that looks and feels more like Facebook than a typical academic system. We have recently begun using CN as a means to engage students in an introductory calculus-based mechanics class, with enrollments of 150-200 students per semester. This article presents basic features of CN, and details our initial experiences and observations.

Life and Microgravity Spacelab (LMS)

NASA Technical Reports Server (NTRS)

Downey, James Patton (Compiler)

1998-01-01

This document reports the results and analyses presented at the Life and Microgravity Spacelab One Year Science Review meeting. The science conference was held in Montreal, Canada, on August 20-21, 1997, and was hosted by the Canadian Space Agency. The LMS payload flew on the Space Shuttle Columbia (STS-78) from June 20 - July 7, 1996. The LMS investigations were performed in a pressurized Spacelab module and the Shuttle middeck. Forty scientific experiments were performed in fields such as fluid physics, solidification of metals, alloys, and semiconductors, the growth of protein crystals, and animal, human, and plant life sciences. The results demonstrate the range of quality science that can be conducted utilizing orbital laboratories in microgravity.

Characterisation of the LMS propagation channel at L- and S-bands: Narrowband experimental data and channel modelling

NASA Technical Reports Server (NTRS)

Sforza, Mario; Buonomo, Sergio

1993-01-01

During the period 1983-1992 the European Space Agency (ESA) carried out several experimental campaigns to investigate the propagation impairments of the Land Mobile Satellite (LMS) communication channel. A substantial amount of data covering quite a large range of elevation angles, environments, and frequencies was obtained. Results from the data analyses are currently used for system planning and design applications within the framework of the future ESA LMS projects. This comprehensive experimental data base is presently utilized also for channel modeling purposes and preliminary results are given. Cumulative Distribution Functions (PDF) and Duration of Fades (DoF) statistics at different elevation angles and environments were also included.

47 CFR 90.355 - LMS operations below 512 MHz.

Code of Federal Regulations, 2010 CFR

2010-10-01

... established, provided that: (a) For transmission between vehicles and base stations, each frequency in a... LMS station and the nearest co-channel base station of another licensee operating a voice system is 75... MHz, 150-170 MHz, and 450-512 MHz bands may use either base-mobile frequencies currently assigned the...

47 CFR 90.359 - Field strength limits for EA-licensed LMS systems.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 5 2010-10-01 2010-10-01 false Field strength limits for EA-licensed LMS systems. 90.359 Section 90.359 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Intelligent Transportation Systems Radio Service § 90.359 Field strength limits for...

Providing Adaptivity in Moodle LMS Courses

ERIC Educational Resources Information Center

Despotovic-Zrakic, Marijana; Markovic, Aleksandar; Bogdanovic, Zorica; Barac, Dusan; Krco, Srdjan

2012-01-01

In this paper, we describe an approach to providing adaptivity in e-education courses. The primary goal of the paper is to enhance an existing e-education system, namely Moodle LMS, by developing a method for creating adaptive courses, and to compare its effectiveness with non-adaptive education approach. First, we defined the basic requirements…

Implementation and performance evaluation of acoustic denoising algorithms for UAV

NASA Astrophysics Data System (ADS)

Chowdhury, Ahmed Sony Kamal

Unmanned Aerial Vehicles (UAVs) have become popular alternative for wildlife monitoring and border surveillance applications. Elimination of the UAV's background noise and classifying the target audio signal effectively are still a major challenge. The main goal of this thesis is to remove UAV's background noise by means of acoustic denoising techniques. Existing denoising algorithms, such as Adaptive Least Mean Square (LMS), Wavelet Denoising, Time-Frequency Block Thresholding, and Wiener Filter, were implemented and their performance evaluated. The denoising algorithms were evaluated for average Signal to Noise Ratio (SNR), Segmental SNR (SSNR), Log Likelihood Ratio (LLR), and Log Spectral Distance (LSD) metrics. To evaluate the effectiveness of the denoising algorithms on classification of target audio, we implemented Support Vector Machine (SVM) and Naive Bayes classification algorithms. Simulation results demonstrate that LMS and Discrete Wavelet Transform (DWT) denoising algorithm offered superior performance than other algorithms. Finally, we implemented the LMS and DWT algorithms on a DSP board for hardware evaluation. Experimental results showed that LMS algorithm's performance is robust compared to DWT for various noise types to classify target audio signals.

Comparison of the hedonic general Labeled Magnitude Scale with the hedonic 9-point scale.

PubMed

Kalva, Jaclyn J; Sims, Charles A; Puentes, Lorenzo A; Snyder, Derek J; Bartoshuk, Linda M

2014-02-01

The hedonic 9-point scale was designed to compare palatability among different food items; however, it has also been used occasionally to compare individuals and groups. Such comparisons can be invalid because scale labels (for example, "like extremely") can denote systematically different hedonic intensities across some groups. Addressing this problem, the hedonic general Labeled Magnitude Scale (gLMS) frames affective experience in terms of the strongest imaginable liking/disliking of any kind, which can yield valid group comparisons of food palatability provided extreme hedonic experiences are unrelated to food. For each scale, 200 panelists rated affect for remembered food products (including favorite and least favorite foods) and sampled foods; they also sampled taste stimuli (quinine, sucrose, NaCl, citric acid) and rated their intensity. Finally, subjects identified experiences representing the endpoints of the hedonic gLMS. Both scales were similar in their ability to detect within-subject hedonic differences across a range of food experiences, but group comparisons favored the hedonic gLMS. With the 9-point scale, extreme labels were strongly associated with extremes in food affect. In contrast, gLMS data showed that scale extremes referenced nonfood experiences. Perceived taste intensity significantly influenced differences in food liking/disliking (for example, those experiencing the most intense tastes, called supertasters, showed more extreme liking and disliking for their favorite and least favorite foods). Scales like the hedonic gLMS are suitable for across-group comparisons of food palatability. © 2014 Institute of Food Technologists®

Special cascade LMS equalization scheme suitable for 60-GHz RoF transmission system.

PubMed

Liu, Siming; Shen, Guansheng; Kou, Yanbin; Tian, Huiping

2016-05-16

We design a specific cascade least mean square (LMS) equalizer and to the best of our knowledge, it is the first time this kind of equalizer has been employed for 60-GHz millimeter-wave (mm-wave) radio over fiber (RoF) system. The proposed cascade LMS equalizer consists of two sub-equalizers which are designated for optical and wireless channel compensations, respectively. We control the linear and nonlinear factors originated from optical link and wireless link separately. The cascade equalization scheme can keep the nonlinear distortions of the RoF system in a low degree. We theoretically and experimentally investigate the parameters of the two sub-equalizers to reach their best performances. The experiment results show that the cascade equalization scheme has a faster convergence speed. It needs a training sequence with a length of 10000 to reach its stable status, which is only half as long as the traditional LMS equalizer needs. With the utility of a proposed equalizer, the 60-GHz RoF system can successfully transmit 5-Gbps BPSK signal over 10-km fiber and 1.2-m wireless link under forward error correction (FEC) limit 10^-3. An improvement of 4dBm and 1dBm in power sensitivity at BER 10^-3 over traditional LMS equalizer can be observed when the signals are transmitted through Back-to-Back (BTB) and 10-km fiber 1.2-m wireless links, respectively.

Tools, Techniques, and Applications: Normalizing the VR Paradigm

NASA Technical Reports Server (NTRS)

Duncan, Gaeme

2008-01-01

Oshynee's precision Learning Objective performance factor rubrics with associated behavioral anchors integrates with Thinking Worlds(TradeMark), to provide event data recording and dynamic prescriptive feedback. Thinking Worlds(TradeMark) provides SCORM parametric data for reporting within the game and within overarching curricula or workplace evaluation strategy. - Open-sourced, browser-based digital dashboard reporting tools collect data from TW, LMS, LCMS, HR, and workplace metrics or control systems The games may be delivered across the internet or in a range of networked and stand-alone methods using the delivery model (s) required by the host organization.

Curative cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy in patients with peritoneal carcinomatosis and synchronous resectable liver metastases arising from colorectal cancer.

PubMed

Lorimier, G; Linot, B; Paillocher, N; Dupoiron, D; Verrièle, V; Wernert, R; Hamy, A; Capitain, O

2017-01-01

This study describes the outcomes of patients with colorectal peritoneal carcinomatosis (PC) with or without liver metastases (LMs) after curative surgery combined with hyperthermic intraperitoneal chemotherapy, in order to assess prognostic factors. Cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) increases overall survival (OS) in patients with PC. The optimal treatment both for PC and for LMs within one surgical operation remains controversial. Patients with PC who underwent CRS followed by HIPEC were evaluated from a prospective database. Overall survival and disease free survival (DFS) rates in patients with PC and with or without LMs were compared. Univariate and multivariate analyses were performed to evaluate predictive variables for survival. From 1999 to 2011, 22 patients with PC and synchronous LMs (PCLM group), were compared to 36 patients with PC alone (PC group). No significant difference was found between the two groups. The median OS were 36 months [range, 20-113] for the PCLM group and 25 months [14-82] for the PC group (p > 0.05) with 5-year OS rates of 38% and 40% respectively (p > 0.05). The median DFS were 9 months [9-20] and 11.8 months [6.5-23] respectively (p = 0.04). The grade III-IV morbidity and cytoreduction score (CCS) >0 (p < 0.05) were identified as independent factors for poor OS. Resections of LMs and CCS >0 impair significantly DFS. Synchronous complete CRS of PC and LMs from a colorectal origin plus HIPEC is a feasible therapeutic option. The improvement in OS is similar to that provided for patients with PC alone. Copyright © 2016 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.

Local morphologic scale: application to segmenting tumor infiltrating lymphocytes in ovarian cancer TMAs

NASA Astrophysics Data System (ADS)

Janowczyk, Andrew; Chandran, Sharat; Feldman, Michael; Madabhushi, Anant

2011-03-01

In this paper we present the concept and associated methodological framework for a novel locally adaptive scale notion called local morphological scale (LMS). Broadly speaking, the LMS at every spatial location is defined as the set of spatial locations, with associated morphological descriptors, which characterize the local structure or heterogeneity for the location under consideration. More specifically, the LMS is obtained as the union of all pixels in the polygon obtained by linking the final location of trajectories of particles emanating from the location under consideration, where the path traveled by originating particles is a function of the local gradients and heterogeneity that they encounter along the way. As these particles proceed on their trajectory away from the location under consideration, the velocity of each particle (i.e. do the particles stop, slow down, or simply continue around the object) is modeled using a physics based system. At some time point the particle velocity goes to zero (potentially on account of encountering (a) repeated obstructions, (b) an insurmountable image gradient, or (c) timing out) and comes to a halt. By using a Monte-Carlo sampling technique, LMS is efficiently determined through parallelized computations. LMS is different from previous local scale related formulations in that it is (a) not a locally connected sets of pixels satisfying some pre-defined intensity homogeneity criterion (generalized-scale), nor is it (b) constrained by any prior shape criterion (ball-scale, tensor-scale). Shape descriptors quantifying the morphology of the particle paths are used to define a tensor LMS signature associated with every spatial image location. These features include the number of object collisions per particle, average velocity of a particle, and the length of the individual particle paths. These features can be used in conjunction with a supervised classifier to correctly differentiate between two different object classes based on local structural properties. In this paper, we apply LMS to the specific problem of classifying regions of interest in Ovarian Cancer (OCa) histology images as either tumor or stroma. This approach is used to classify lymphocytes as either tumor infiltrating lymphocytes (TILs) or non-TILs; the presence of TILs having been identified as an important prognostic indicator for disease outcome in patients with OCa. We present preliminary results on the tumor/stroma classification of 11,000 randomly selected locations of interest, across 11 images obtained from 6 patient studies. Using a Probabilistic Boosting Tree (PBT), our supervised classifier yielded an area under the receiver operation characteristic curve (AUC) of 0.8341 +/-0.0059 over 5 runs of randomized cross validation. The average LMS computation time at every spatial location for an image patch comprising 2000 pixels with 24 particles at every location was only 18s.

The linearized multistage model and the future of quantitative risk assessment.

PubMed

Crump, K S

1996-10-01

The linearized multistage (LMS) model has for over 15 years been the default dose-response model used by the U.S. Environmental Protection Agency (USEPA) and other federal and state regulatory agencies in the United States for calculating quantitative estimates of low-dose carcinogenic risks from animal data. The LMS model is in essence a flexible statistical model that can describe both linear and non-linear dose-response patterns, and that produces an upper confidence bound on the linear low-dose slope of the dose-response curve. Unlike its namesake, the Armitage-Doll multistage model, the parameters of the LMS do not correspond to actual physiological phenomena. Thus the LMS is 'biological' only to the extent that the true biological dose response is linear at low dose and that low-dose slope is reflected in the experimental data. If the true dose response is non-linear the LMS upper bound may overestimate the true risk by many orders of magnitude. However, competing low-dose extrapolation models, including those derived from 'biologically-based models' that are capable of incorporating additional biological information, have not shown evidence to date of being able to produce quantitative estimates of low-dose risks that are any more accurate than those obtained from the LMS model. Further, even if these attempts were successful, the extent to which more accurate estimates of low-dose risks in a test animal species would translate into improved estimates of human risk is questionable. Thus, it does not appear possible at present to develop a quantitative approach that would be generally applicable and that would offer significant improvements upon the crude bounding estimates of the type provided by the LMS model. Draft USEPA guidelines for cancer risk assessment incorporate an approach similar to the LMS for carcinogens having a linear mode of action. However, under these guidelines quantitative estimates of low-dose risks would not be developed for carcinogens having a non-linear mode of action; instead dose-response modelling would be used in the experimental range to calculate an LED10* (a statistical lower bound on the dose corresponding to a 10% increase in risk), and safety factors would be applied to the LED10* to determine acceptable exposure levels for humans. This approach is very similar to the one presently used by USEPA for non-carcinogens. Rather than using one approach for carcinogens believed to have a linear mode of action and a different approach for all other health effects, it is suggested herein that it would be more appropriate to use an approach conceptually similar to the 'LED10*-safety factor' approach for all health effects, and not to routinely develop quantitative risk estimates from animal data.

A miniature laser ablation mass spectrometer for quantitative in situ chemical composition investigation of lunar surface

NASA Astrophysics Data System (ADS)

Brigitte Neuland, Maike; Grimaudo, Valentine; Mezger, Klaus; Moreno-García, Pavel; Riedo, Andreas; Tulej, Marek; Wurz, Peter

2016-04-01

The chemical composition of planetary bodies, moons, comets and asteroids is a key to understand their origin and evolution [Wurz,2009]. Measurements of the elemental and isotopic composition of rocks yield information about the formation of the planetary body, its evolution and following processes shaping the planetary surface. From the elemental composition, conclusions about modal mineralogy and petrology can be drawn. Isotope ratios are a sensitive indicator for past events on the planetary body and yield information about origin and transformation of the matter, back to events that occurred in the early solar system. Finally, measurements of radiogenic isotopes make it possible to carry out dating analyses. All these topics, particularly in situ dating analyses, quantitative elemental and highly accurate isotopic composition measurements, are top priority scientific questions for future lunar missions. An instrument for precise measurements of chemical composition will be a key element in scientific payloads of future landers or rovers on lunar surface. We present a miniature laser ablation mass spectrometer (LMS) designed for in situ research in planetary and space science and optimised for measurements of the chemical composition of rocks and soils on a planetary surface. By means of measurements of standard reference materials we demonstrate that LMS is a suitable instrument for in situ measurements of elemental and isotopic composition with high precision and accuracy. Measurements of soil standards are used to confirm known sensitivity coefficients of the instrument and to prove the power of LMS for quantitative elemental analyses [Neuland,2016]. For demonstration of the capability of LMS to measure the chemical composition of extraterrestrial material we use a sample of Allende meteorite [Neuland,2014]. Investigations of layered samples confirm the high spatial resolution in vertical direction of LMS [Grimaudo,2015], which allows in situ studying of past surface processes on a planetary surface. Analyses of Pb isotopes show that the statistical uncertainty for the age determination by LMS is about ±100 Myrs, if abundance of 206Pb and 207Pb is 20ppm and 2ppm respectively [Riedo,2013]. These Pb isotopes have abundances of tens to hundreds of ppm in lunar KREEP [Nemchin,2008]. We demonstrate the measurement capabilities of LMS for petrographic and mineralogical analyses, for isotopic studies and dating analyses, which are key topics for future missions to the Moon. Having the LMS instrument installed on a lunar rover would allow measuring the chemical composition of many rock and soil samples, distributed over a certain area, inside the South Pole Aitken Basin for example. LMS measurements would yield valuable conclusions about age and mineralogy. References: [Wurz,2009]Wurz,P. et al. 2009, AIP Conf.Proc., CP1144:70-75. [Grimaudo,2015]Grimaudo, V. et al. 2015, Anal.Chem. 87: 2037-2041. [Neuland,2014]Neuland, M.B. et al. 2014, Planet.Space Sci.101:196-209. [Neuland,2016]Neuland M.B. et al. 2016, Meas. Sci. Technol.,submitted. [Riedo,2013]Riedo A. et al., 2013 Planet. Space Sci. 87: 1-13. [Nemchin,2008]Nemchin et al., 2008 Geochim. Cosmochim.Acta 72:668-689.

Space Acceleration Measurement System (SAMS)/Orbital Acceleration Research Experiment (OARE)

NASA Technical Reports Server (NTRS)

Hakimzadeh, Roshanak

1998-01-01

The Life and Microgravity Spacelab (LMS) payload flew on the Orbiter Columbia on mission STS-78 from June 20th to July 7th, 1996. The LMS payload on STS-78 was dedicated to life sciences and microgravity experiments. Two accelerometer systems managed by the NASA Lewis Research Center (LERC) flew to support these experiments, namely the Orbital Acceleration Research Experiment (OARE) and the Space Acceleration Measurements System (SAMS). In addition, the Microgravity Measurement Assembly (NOAA), managed by the European Space Research and Technology Center (ESA/ESTEC), and sponsored by NASA, collected acceleration data in support of the experiments on-board the LMS mission. OARE downlinked real-time quasi-steady acceleration data, which was provided to the investigators. The SAMS recorded higher frequency data on-board for post-mission analysis. The MMA downlinked real-time quasi-steady as well as higher frequency acceleration data, which was provided to the investigators. The Principal Investigator Microgravity Services (PIMS) project at NASA LERC supports principal investigators of microgravity experiments as they evaluate the effects of varying acceleration levels on their experiments. A summary report was prepared by PIMS to furnish interested experiment investigators with a guide to evaluate the acceleration environment during STS-78, and as a means of identifying areas which require further study. The summary report provides an overview of the STS-78 mission, describes the accelerometer systems flown on this mission, discusses some specific analyses of the accelerometer data in relation to the various activities which occurred during the mission, and presents plots resulting from these analyses as a snapshot of the environment during the mission. Numerous activities occurred during the STS-78 mission that are of interest to the low-gravity community. Specific activities of interest during this mission were crew exercise, radiator deployment, Vernier Reaction Control System (VRCS) reboost, venting operations, Flight Control System (FCS) checkout, rack excitation, operation of the Life Sciences Laboratory Equipment Refrigerator/Freezer (LSLE R/F), operation of the JSC Projects Centrifuge, crew sleep, and attitude changes. The low-gravity environment related to these activities is discussed in the summary report.

Efficacy of OK-432 sclerotherapy in treatment of lymphatic malformations: long-term follow-up results.

PubMed

Weitz-Tuoretmaa, Annamaria; Rautio, Riitta; Valkila, Jan; Keski-Säntti, Harri; Keski-Nisula, Leo; Laranne, Jussi

2014-02-01

Lymphatic malformations (LMs) are rare congenital tumors of the lymphatic system often affecting the head and neck area. Because of cosmetic and functional symptoms most patients need to be treated. Traditionally surgical treatment has been considered to be the first-line treatment for LM. However, it is challenging because of the need for complete excision. The risk of poor cosmetic result and damage to surrounding structures is high. Since Ogita presented OK-432 as a treatment for LM in 1987, it has been widely used as the primary treatment. Many papers have been published on this topic but with relatively short follow-up times. We present a material of 36 LMs treated with OK-432 during the period of 1999-2009 and with an average follow-up time of 6 years. Immediate post-treatment results were compared with the late follow-up findings. Primary and late response to therapy was evaluated with an MRI scan by measuring the change in lesion size. At the follow-up visit, all patients were clinically examined and they answered a symptom questionnaire. Later 26/36 patients were also available for a quality of life questionnaire. Primarily 67% demonstrated a complete or marked response. At the follow-up 64% showed a complete or marked response, in 11% the final response was better than the initially observed and only 2 patients had relapsed. The initial response predicted the long-term outcome accurately and the effect of OK-432 sclerotherapy seems to be long lasting. According to the MRI evaluation 80% and subjectively 94% of the patients benefitted from the treatment. Quality of life questionnaire showed high post-treatment satisfaction. We found OK-432 sclerotherapy to be a safe and effective treatment with a long lasting effect in the management of macrocystic LMs.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tyrrell, Evan; Denny, Angelita

Fifty-two groundwater samples and one surface water sample were collected at the Monument Valley, Arizona, Processing Site to monitor groundwater contaminants for evaluating the effectiveness of the proposed compliance strategy as specified in the 1999 Final Site Observational Work Plan for the UMTRA Project Site at Monument Valley, Arizona. Sampling and analyses were conducted as specified in the Sampling and Analysis Plan for U.S. Department of Energy Office of Legacy Management Sites (LMS/PRO/S04351, continually updated, http://energy.gov/lm/downloads/sampling-and-analysis-plan-us-department- energy-office-legacy-management-sites). Samples were collected for metals, anions, nitrate + nitrite as N, and ammonia as N analyses at all locations.

The Library Media Specialist's Role in Teaching Online Safety

ERIC Educational Resources Information Center

Schmidt, Cynthia Martin

2009-01-01

Many school library media specialists (LMS) would gladly pass along the responsibility of teaching online safety. Others may feel that it is the job of the computer lab personnel, the classroom teacher, or the parent. So how does the LMS fit into this scenario? While it is certainly appropriate for parents and classroom teachers to take joint…

Adaptive Multi-Layer LMS Controller Design and Application to Active Vibration Suppression on a Truss and Proposed Impact Analysis Technique

DTIC Science & Technology

2001-06-01

Setup and Initiation ........................................................ 83 2. Simulation 1 (19 Hz, Y-axis of Node 18, Piezo #2...175 INITIAL DISTRIBUTION LIST ................................................................................... 187 ix...system for the sake of testing and simplicity. The Adaptive Multi-Layered LMS Controller was developed one piece at a time. After initial experimental

Measured results of polarization crosstalk cancellation using LMS control. [Least Mean Square

NASA Technical Reports Server (NTRS)

Baird, C. A.; Rassweiler, G. G.

1977-01-01

This paper discusses the use of wideband decoupling networks for the cancellation of polarization crosstalk in dual-polarized communication links. Measured cancellation performance for an all-electronic IF network and an RF electro-mechanical waveguide network are presented. Each of these networks utilizes LMS-type adaptive control techniques to adjust the cancellation network.

Primary thyroid leiomyosarcoma: a case report and review of the literature

PubMed Central

CANU, G.L.; BULLA, J.S.; LAI, M.L.; MEDAS, F.; BAGHINO, G.; ERDAS, E.; MARIOTTI, S.

2018-01-01

Primary thyroid leiomyosarcoma (LMS) is an extremely rare tumor. We report a case of a 47-year-old male with a rapidly growing neck mass and disfagia. Preoperative investigations were diagnostic of anaplastic carcinoma. Total thyroidectomy with partial esophagectomy and dissection of right infrahyoid muscles was performed. Through histolological and immunohistochemical evaluations a primary thyroid high-grade LMS was diagnosed. At 2 months of follow-up a local recurrence was detected and consequently the patient was submitted to chemotherapy with partial response. He is still alive 9 months after surgery. Diagnosis of primary thyroid LMS is difficult due to its similarity to other more common thyroid tumors. To date, there is no standard therapy and prognosis is poor. PMID:29549682

Primary thyroid leiomyosarcoma: a case report and review of the literature.

PubMed

Canu, G L; Bulla, J S; Lai, M L; Medas, F; Baghino, G; Erdas, E; Mariotti, S; Calò, P G

2018-01-01

Primary thyroid leiomyosarcoma (LMS) is an extremely rare tumor. We report a case of a 47-year-old male with a rapidly growing neck mass and disfagia. Preoperative investigations were diagnostic of anaplastic carcinoma. Total thyroidectomy with partial esophagectomy and dissection of right infrahyoid muscles was performed. Through histolological and immunohistochemical evaluations a primary thyroid high-grade LMS was diagnosed. At 2 months of follow-up a local recurrence was detected and consequently the patient was submitted to chemotherapy with partial response. He is still alive 9 months after surgery. Diagnosis of primary thyroid LMS is difficult due to its similarity to other more common thyroid tumors. To date, there is no standard therapy and prognosis is poor.

Scene-based nonuniformity correction with reduced ghosting using a gated LMS algorithm.

PubMed

Hardie, Russell C; Baxley, Frank; Brys, Brandon; Hytla, Patrick

2009-08-17

In this paper, we present a scene-based nouniformity correction (NUC) method using a modified adaptive least mean square (LMS) algorithm with a novel gating operation on the updates. The gating is designed to significantly reduce ghosting artifacts produced by many scene-based NUC algorithms by halting updates when temporal variation is lacking. We define the algorithm and present a number of experimental results to demonstrate the efficacy of the proposed method in comparison to several previously published methods including other LMS and constant statistics based methods. The experimental results include simulated imagery and a real infrared image sequence. We show that the proposed method significantly reduces ghosting artifacts, but has a slightly longer convergence time. (c) 2009 Optical Society of America

January 2012 Groundwater Sampling at the Gnome-Coach, New Mexico, Site (Data Validation Package)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Findlay, Richard C.

2012-12-01

Annual sampling was conducted January 18, 2012, to monitor groundwater for potential radionuclide contamination at the Gnome-Coach site in New Mexico. The sampling was performed as specified in the Sampling and Analysis Plan for U.S. Department of Energy Office of Legacy Management Sites (LMS/PLN/S04351, continually updated). Well LRL-7 was not sampled per instruction from the lead. A duplicate sample was collected from well USGS-1 and water levels were measured in the monitoring wells onsite.

January 2011 Groundwater Sampling at the Gnome-Coach, New Mexico, Site (Data Validation Package)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Findlay, Richard C.

2011-11-01

Annual sampling was conducted January 19, 2011, to monitor groundwater for potential radionuclide contamination at the Gnome-Coach site in New Mexico. The sampling was performed as specified in the Sampling and Analysis Plan for U.S. Department of Energy Office of Legacy Management Sites (LMS/PLN/S04351, continually updated). Well LRL-7 was not sampled per instruction from the lead. A duplicate sample was collected from well USGS-1.Water levels were measured in the monitoring wells onsite.

Self Managing the Consequences of Major Limb Trauma

DTIC Science & Technology

2011-08-01

Nathan M. Parmer, Psy.D. 5e. TASK NUMBER E -Mail: emackenz@jhsph.edu 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES...individual’s lesson activity. This area includes the ‘Member Lounge ’, which is an open virtual chat space where all users from any cohort or class can...current lesson, and allows the program administrator to send e -mail reminders when users fall behind on the sessions. The LMS is integrated to the

GLORIA observations of de-/nitrification during the Arctic winter 2015/16 POLSTRACC campaign

NASA Astrophysics Data System (ADS)

Braun, Marleen; Woiwode, Wolfgang; Höpfner, Michael; Johansson, Sören; Friedl-Vallon, Felix; Oelhaf, Hermann; Preusse, Peter; Ungermann, Jörn; Grooß, Jens-Uwe; Jurkat, Tina; Khosrawi, Farahnaz; Kirner, Ole; Marsing, Andreas; Sinnhuber, Björn-Martin; Voigt, Christiane; Ziereis, Helmut; Orphal, Johannes

2017-04-01

Denitrification, the condensation and sedimentation of HNO3-containing particles in the winter stratosphere at high latitudes, is an important process affecting the deactivation of ozone-depleting halogen species. It modulates the vertical partitioning of chemically active NOy and the vertical redistribution of HNO3 can affect low stratospheric altitudes under sufficiently cold conditions. The capability of associated nitrification to disturb the NOy budget of the climate-relevant lowermost stratosphere (LMS) has hardly been investigated in detail and represents a challenge for model simulations. The Arctic winter 2015/16 was characterized by exceptionally cold stratospheric temperatures and widespread polar stratospheric clouds (PSCs) that were observed from mid-December 2015 until the end of February 2016 down to the LMS. Observations by the GLORIA (Gimballed Limb Observer for Radiance Imaging of the Atmosphere) spectrometer during the POLSTRACC (Polar Stratosphere in a Changing Climate) aircraft mission allow us to study the development of nitrification of the Arctic LMS during and after the 2015/16 PSC period with high vertical resolution. The vertical cross-sections of HNO3 distribution along the HALO (High Altitude and LOng range research aircraft) flight tracks derived from GLORIA observations show the result of significant vertical redistribution of NOy with strong nitrification of up to 6 ppbv in the LMS. We compare the results of the GLORIA observations with simulations by the state-of-the-art chemical-transport model CLaMS and the climate-chemistry model EMAC and discuss the capability of these models to reproduce nitrification of the Arctic LMS.

Understanding and controlling low-temperature aging of nanocrystalline materials.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Battaile, Corbett Chandler; Boyce, Brad Lee; Brons, Justin G.

2013-10-01

Nanocrystalline copper lms were created by both repetitive high-energy pulsed power, to produce material without internal nanotwins; and pulsed laser deposition, to produce nan- otwins. Samples of these lms were indented at ambient (298K) and cryogenic temperatures by immersion in liquid nitrogen (77K) and helium (4K). The indented samples were sectioned through the indented regions and imaged in a scanning electron microscope. Extensive grain growth was observed in the lms that contained nanotwins and were indented cryogenically. The lms that either lacked twins, or were indented under ambient conditions, were found to exhibit no substantial grain growth by visual inspection.more » Precession transmission elec- tron microscopy was used to con rm these ndings quantitatively, and show that 3 and 7 boundaries proliferate during grain growth, implying that these interface types play a key role in governing the extensive grain growth observed here. Molecular dynamics sim- ulations of the motion of individual grain boundaries demonstrate that speci c classes of boundaries - notably 3 and 7 - exhibit anti- or a-thermal migration, meaning that their mobilities either increase or do not change signi cantly with decreasing temperature. An in-situ cryogenic indentation capability was developed and implemented in a transmission electron microscope. Preliminary results do not show extensive cryogenic grain growth in indented copper lms. This discrepancy could arise from the signi cant di erences in con g- uration and loading of the specimen between the two approaches, and further research and development of this capability is needed.« less

Exploring the Link between Online Behaviours and Course Performance in Asynchronous Online High School Courses

ERIC Educational Resources Information Center

Lowes, Susan; Lin, Peiyi; Kinghorn, Brian

2015-01-01

As enrolment in online courses has grown and LMS data has become accessible for analysis, researchers have begun to examine the link between in-course behaviours and course outcomes. This paper explores the use of readily available LMS data generated by approximately 700 students enrolled in the 12 online courses offered by Pamoja Education, the…

Astronaut Richard M. Linnehan, mission specialist, works out in the Life and Microgravity Spacelab

NASA Technical Reports Server (NTRS)

1996-01-01

STS-78 ONBOARD VIEW --- Astronaut Richard M. Linnehan, mission specialist, works out in the Life and Microgravity Spacelab (LMS-1) Science Module aboard the Earth-orbiting Space Shuttle Columbia. With an almost 17-day mission away from Earths gravity, crew members maintained an exercise regimen above and beyond their assigned LMS-1 duty assignments.

In vitro effects of anthelmintics on the histochemistry of Haemonchus contortus and Trichuris globulosa.

PubMed

Kaur, M; Sood, M L

1996-12-01

In vitro incubation of Haemonchus contortus (RUD., 1803) and Trichuris globulosa (v. LINSTOW, 1901) were proformed for 10-12 h in Tyrode's solution and 10 and 50 micrograms/ml concentrations each of albendazole (ABZ), fenbendazole (FBZ), thiophenate (TP), dl-tetramisole and oxyclozanide (TO), dl-tetramisole HCI (TMS) and levamisole HCI (LMS) to study morphological and histochemical alterations. The major structural changes observed after treatment with all the drugs were vacuolation in the intestine of H. contortus except with TP treatment and disruption of the epithelium in T. globulosa except with TMS treatment. The other major alteration in T. globulosa was the loss of muscle striations after TP, TO, TMS and LMS treatments. All the six anthelmintics reduced the quantity of neutral mucopolysaccharides in the intestine of H. contortus and T. globulosa except with TMS and LMS treatments in the latter. Acidic mucopolysaccharides detected in the microvilli of the intestine of H. contortus were lost after TO and ABZ treatments. The loss of lipids from the intestine was evident after TO, ABZ, FBZ and TP treatments in H. contortus and by all the drugs in T. globulosa. LMS treatment caused accumulation of very large lipid droplets in the intestine of H. contortus.

VizieR Online Data Catalog: HerMES Large Mode Survey catalogue (Asboth+, 2016)

NASA Astrophysics Data System (ADS)

Asboth, V.; Conley, A.; Sayers, J.; Bethermin, M.; Chapman, S. C.; Clements, D. L.; Cooray, A.; Dannerbauer, H.; Farrah, D.; Glenn, J.; Golwala, S. R.; Halpern, M.; Ibar, E.; Ivison, R. J.; Maloney, P. R.; Marques-Chaves, R.; Martinez-Navajas, P. I.; Oliver, S. J.; Perez-Fournon, I.; Riechers, D. A.; Rowan-Robinson, M.; Scott, D.; Siegel, S. R.; Vieira, J. D.; Viero, M.; Wang, L.; Wardlow, J.; Wheeler, J.

2018-01-01

The HerMES Large Mode Survey (HeLMS) consists of a large area shallow observation of an equatorial field at wavelengths of 250, 350 and 500um, obtained using the SPIRE aboard the Herschel Space Observatory. HeLMS is an extension of HerMES (Oliver et al., 2012MNRAS.424.1614O, Cat. VIII/95 and VIII/103), a 'wedding cake' type survey containing small and deep maps and larger shallower observations of different fields. HeLMS covers about 302deg2 of the sky, making it the largest area observed in the HerMES. The HeLMS field spans 23h14m

Postoperative occipital neuralgia in posterior upper cervical spine surgery: a systematic review.

PubMed

Guan, Qing; Xing, Fei; Long, Ye; Xiang, Zhou

2017-11-07

Postoperative occipital neuralgia (PON) after upper cervical spine surgery can cause significant morbidity and may be overlooked. The causes, presentation, diagnosis, management, prognosis, and prevention of PON were reviewed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. English-language studies and case reports published from inception to 2017 were retrieved. Data on surgical procedures, incidence, cause of PON, management, outcomes, and preventive technique were extracted. Sixteen articles, including 591 patients, were selected; 93% of the patients with PON underwent C1 lateral mass screw (C1LMS) fixation, with additional 7% who underwent occipitocervical fusion without C1 fixation. PON had an incidence that ranged from 1 to 35% and was transient in 34%, but persistent in 66%. Five articles explained the possible causes. The primary presentation was constant or paroxysmal burning pain located mainly in the occipital and upper neck area and partially extending to the vertical, retroauricular, retromandibular, and forehead zone. Treatment included medications, nerve block, revision surgery, and nerve stimulation. Two prospective studies compared the effect of C2 nerve root transection on PON. PON in upper cervical spine surgery is a debilitating complication and was most commonly encountered by patients undergoing C1LMS fixation. The etiology of PON is partially clear, and the pain could be persistent and hard to cure. Reducing the incidence of PON can be realized by improving technique. More high-quality prospective studies are needed to define the effect of C2 nerve root transection on PON.

Odel of Dynamic Integration of Lean Shop Floor Management Within the Organizational Management System

NASA Astrophysics Data System (ADS)

Iuga, Virginia; Kifor, Claudiu

2014-12-01

The key to achieve a sustainable development lies in the customer satisfaction through improved quality, reduced cost, reduced delivery lead times and proper communication. The objective of the lean manufacturing system (LMS) is to identify and eliminate the processes and resources which do not add value to a product. The following paper aims to present a proposal of further development of integrated management systems in organizations through the implementation of lean shop floor management. In the first part of the paper, a dynamic model of the implementation steps will be presented. Furthermore, the paper underlines the importance of implementing a lean culture parallel with each step of integrating the lean methods and tools. The paper also describes the Toyota philosophy, tools, and the supporting lean culture necessary to implementing an efficient lean system in productive organizations

The Development of E-Portfolio Evaluation Criteria and Application to the Blackboard LMS E-Portfolio

ERIC Educational Resources Information Center

McKenna, Gary F.; Stansfield, Mark H.

2012-01-01

The purpose of this paper is to develop e-portfolio evaluation criteria which will be used to review the Blackboard LMS e-portfolio being used at one Higher Education (HE) institution in the UK as evaluation criteria for reviewing e-portfolio provision does not exist in the literature. The approach taken was to initiate a wide literature search…

Butterfly, Recurrence, and Predictability in Lorenz Models

NASA Astrophysics Data System (ADS)

Shen, B. W.

2017-12-01

Over the span of 50 years, the original three-dimensional Lorenz model (3DLM; Lorenz,1963) and its high-dimensional versions (e.g., Shen 2014a and references therein) have been used for improving our understanding of the predictability of weather and climate with a focus on chaotic responses. Although the Lorenz studies focus on nonlinear processes and chaotic dynamics, people often apply a "linear" conceptual model to understand the nonlinear processes in the 3DLM. In this talk, we present examples to illustrate the common misunderstandings regarding butterfly effect and discuss the importance of solutions' recurrence and boundedness in the 3DLM and high-dimensional LMs. The first example is discussed with the following folklore that has been widely used as an analogy of the butterfly effect: "For want of a nail, the shoe was lost.For want of a shoe, the horse was lost.For want of a horse, the rider was lost.For want of a rider, the battle was lost.For want of a battle, the kingdom was lost.And all for the want of a horseshoe nail."However, in 2008, Prof. Lorenz stated that he did not feel that this verse described true chaos but that it better illustrated the simpler phenomenon of instability; and that the verse implicitly suggests that subsequent small events will not reverse the outcome (Lorenz, 2008). Lorenz's comments suggest that the verse neither describes negative (nonlinear) feedback nor indicates recurrence, the latter of which is required for the appearance of a butterfly pattern. The second example is to illustrate that the divergence of two nearby trajectories should be bounded and recurrent, as shown in Figure 1. Furthermore, we will discuss how high-dimensional LMs were derived to illustrate (1) negative nonlinear feedback that stabilizes the system within the five- and seven-dimensional LMs (5D and 7D LMs; Shen 2014a; 2015a; 2016); (2) positive nonlinear feedback that destabilizes the system within the 6D and 8D LMs (Shen 2015b; 2017); and (3) recurrence (e.g., quasi-periodic solutions) within non-dissipative LMs (Faghih-Naini and Shen, 2017; Shen and Faghih-Naini, 2017). http://bwshen.sdsu.edu/shen_agu17.html

A New Z Score Curve of the Coronary Arterial Internal Diameter Using the Lambda-Mu-Sigma Method in a Pediatric Population.

PubMed

Kobayashi, Tohru; Fuse, Shigeto; Sakamoto, Naoko; Mikami, Masashi; Ogawa, Shunichi; Hamaoka, Kenji; Arakaki, Yoshio; Nakamura, Tsuneyuki; Nagasawa, Hiroyuki; Kato, Taichi; Jibiki, Toshiaki; Iwashima, Satoru; Yamakawa, Masaru; Ohkubo, Takashi; Shimoyama, Shinya; Aso, Kentaro; Sato, Seiichi; Saji, Tsutomu

2016-08-01

Several coronary artery Z score models have been developed. However, a Z score model derived by the lambda-mu-sigma (LMS) method has not been established. Echocardiographic measurements of the proximal right coronary artery, left main coronary artery, proximal left anterior descending coronary artery, and proximal left circumflex artery were prospectively collected in 3,851 healthy children ≤18 years of age and divided into developmental and validation data sets. In the developmental data set, smooth curves were fitted for each coronary artery using linear, logarithmic, square-root, and LMS methods for both sexes. The relative goodness of fit of these models was compared using the Bayesian information criterion. The best-fitting model was tested for reproducibility using the validation data set. The goodness of fit of the selected model was visually compared with that of the previously reported regression models using a Q-Q plot. Because the internal diameter of each coronary artery was not similar between sexes, sex-specific Z score models were developed. The LMS model with body surface area as the independent variable showed the best goodness of fit; therefore, the internal diameter of each coronary artery was transformed into a sex-specific Z score on the basis of body surface area using the LMS method. In the validation data set, a Q-Q plot of each model indicated that the distribution of Z scores in the LMS models was closer to the normal distribution compared with previously reported regression models. Finally, the final models for each coronary artery in both sexes were developed using the developmental and validation data sets. A Microsoft Excel-based Z score calculator was also created, which is freely available online (http://raise.umin.jp/zsp/calculator/). Novel LMS models with which to estimate the sex-specific Z score of each internal coronary artery diameter were generated and validated using a large pediatric population. Copyright © 2016 American Society of Echocardiography. Published by Elsevier Inc. All rights reserved.

How the study of online collaborative learning can guide teachers and predict students' performance in a medical course.

PubMed

Saqr, Mohammed; Fors, Uno; Tedre, Matti

2018-02-06

Collaborative learning facilitates reflection, diversifies understanding and stimulates skills of critical and higher-order thinking. Although the benefits of collaborative learning have long been recognized, it is still rarely studied by social network analysis (SNA) in medical education, and the relationship of parameters that can be obtained via SNA with students' performance remains largely unknown. The aim of this work was to assess the potential of SNA for studying online collaborative clinical case discussions in a medical course and to find out which activities correlate with better performance and help predict final grade or explain variance in performance. Interaction data were extracted from the learning management system (LMS) forum module of the Surgery course in Qassim University, College of Medicine. The data were analyzed using social network analysis. The analysis included visual as well as a statistical analysis. Correlation with students' performance was calculated, and automatic linear regression was used to predict students' performance. By using social network analysis, we were able to analyze a large number of interactions in online collaborative discussions and gain an overall insight of the course social structure, track the knowledge flow and the interaction patterns, as well as identify the active participants and the prominent discussion moderators. When augmented with calculated network parameters, SNA offered an accurate view of the course network, each user's position, and level of connectedness. Results from correlation coefficients, linear regression, and logistic regression indicated that a student's position and role in information relay in online case discussions, combined with the strength of that student's network (social capital), can be used as predictors of performance in relevant settings. By using social network analysis, researchers can analyze the social structure of an online course and reveal important information about students' and teachers' interactions that can be valuable in guiding teachers, improve students' engagement, and contribute to learning analytics insights.

Automated chromatographic laccase-mediator-system activity assay.

PubMed

Anders, Nico; Schelden, Maximilian; Roth, Simon; Spiess, Antje C

2017-08-01

To study the interaction of laccases, mediators, and substrates in laccase-mediator systems (LMS), an on-line measurement was developed using high performance anion exchange chromatography equipped with a CarboPac™ PA 100 column coupled to pulsed amperometric detection (HPAEC-PAD). The developed method was optimized for overall chromatographic run time (45 to 120 min) and automated sample drawing. As an example, the Trametes versicolor laccase induced oxidation of 1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)-1,3-dihydroxypropane (adlerol) using 1-hydroxybenzotriazole (HBT) as mediator was measured and analyzed on-line. Since the Au electrode of the PAD detects only hydroxyl group containing substances with a limit of detection being in the milligram/liter range, not all products are measureable. Therefore, this method was applied for the quantification of adlerol, and-based on adlerol conversion-for the quantification of the LMS activity at a specific T. versicolor laccase/HBT ratio. The automated chromatographic activity assay allowed for a defined reaction start of all laccase-mediator-system reactions mixtures, and the LMS reaction progress was automatically monitored for 48 h. The automatization enabled an integrated monitoring overnight and over-weekend and minimized all manual errors such as pipetting of solutions accordingly. The activity of the LMS based on adlerol consumption was determined to 0.47 U/mg protein for a laccase/mediator ratio of 1.75 U laccase/g HBT. In the future, the automated method will allow for a fast screening of combinations of laccases, mediators, and substrates which are efficient for lignin modification. In particular, it allows for a fast and easy quantification of the oxidizing activity of an LMS on a lignin-related substrate which is not covered by typical colorimetric laccase assays. ᅟ.

Radiographic Evidence of Sinonasal Inflammation in Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome: An Underrecognized Association.

PubMed

Hamada, Satoshi; Tatsumi, Shuji; Kobayashi, Yoshiki; Matsumoto, Hisako; Yasuba, Hirotaka

Sinonasal inflammation on both clinical examinations and imaging significantly impacts both asthma and chronic obstructive pulmonary disease (COPD). The objective of this study was to examine the association between sinonasal inflammation and asthma-COPD overlap syndrome (ACOS). A total of 112 patients with a ratio of forced expiratory volume in 1 s to forced vital capacity of less than 70% were enrolled. COPD, asthma, and ACOS were clinically diagnosed according to the 2014 Global Initiative for Asthma and Global Initiative for Chronic Obstructive Lung Disease guidelines. Sinonasal inflammatory condition was evaluated using sinus computed tomography, and its severity was assessed according to the Lund-Mackay staging (LMS) system. Ethmoid sinus-dominant shadow was defined as the presence of greater LMS scores for the anterior and posterior ethmoid sinuses than for the maxillary sinus. COPD, asthma, and ACOS were diagnosed in 55 (49.1%), 39 (34.8%), and 18 patients (16.1%), respectively. The frequency of radiographic evidence of sinonasal inflammation in patients with COPD, asthma, ACOS was 60.0%, 94.9%, and 72.2%, respectively. Patients with ACOS and COPD had only mild radiographic evidence of sinonasal inflammation (LMS score, 1-7), whereas moderate (LMS score, 8-11) and severe (LMS score, ≥12) radiographic evidence of sinonasal inflammation were detected only in patients with asthma. Furthermore, the frequency of ethmoid sinus-dominant shadow was significantly higher in patients with asthma than in those with COPD and ACOS. Radiographic evidence of sinonasal inflammation was a common comorbidity in ACOS. Future studies are required to examine the role of sinonasal inflammation in ACOS. Copyright © 2017 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

Taurus lightweight manned spacecraft Earth orbiting vehicle

NASA Technical Reports Server (NTRS)

Chase, Kevin A.; Vandersall, Eric J.; Plotkin, Jennifer; Travisano, Jeffrey J.; Loveless, Dennis; Kaczmarek, Michael; White, Anthony G.; Est, Andy; Bulla, Gregory; Henry, Chris

1991-01-01

The Taurus Lightweight Manned Spacecraft (LMS) was developed by students of the University of Maryland's Aerospace Engineering course in Space Vehicle Design. That course required students to design an Alternative Manned Spacecraft (AMS) to augment or replace the Space Transportation System and meet the following design requirements: (1) launch on the Taurus Booster being developed by Orbital Sciences Corporation; (2) 99.9 percent assured crew survival rate; (3) technology cutoff data of 1 Jan. 1991; (4) compatibility with current space administration infrastructure; and (5) first flight by May 1995. The Taurus LMS design meets the above requirements and represents an initial step towards larger and more complex spacecraft. The Taurus LMS has a very limited application when compared to the Space Shuttle, but it demonstrates that the U.S. can have a safe, reliable, and low cost space system. The Taurus LMS is a short mission duration spacecraft designed to place one man into low earth orbit (LEO). The driving factor for this design was the low payload carrying capabilities of the Taurus Booster--1300 kg to a 300 km orbit. The Taurus LMS design is divided into six major design sections. The human factors system deals with the problems of life support and spacecraft cooling. The propulsion section contains the abort system, the Orbital Maneuvering System (OMS), the Reaction Control System (RCS), and power generation. The thermal protection systems and spacecraft structure are contained in the structures section. The avionics section includes navigation, attitude determination, data processing, communication systems, and sensors. The mission analysis section was responsible for ground processing and spacecraft astrodynamics. The systems integration section pulled the above sections together into one spacecraft and addressed costing and reliability.

Taurus Lightweight Manned Spacecraft Earth orbiting vehicle

NASA Technical Reports Server (NTRS)

Bosset, M.

1991-01-01

The Taurus Lightweight Manned Spacecraft (LMS) was developed by students of the University of Maryland's Aerospace Engineering course in Space Vehicle Design. That course required students to design an Alternative Manned Spacecraft (AMS) to augment or replace the Space Transportation System and meet the following design requirements: (1) launch on the Taurus Booster being developed by Orbital Sciences Corporation; (2) 99.9 percent assured crew survival rate; (3) technology cutoff date of 1 Jan. 1991; (4) compatibility with current space administration infrastructure; and (5) first flight by May 1995. The Taurus LMS design meets the above requirements and represents an initial step toward larger and more complex spacecraft. The Taurus LMS has a very limited application when compared to the space shuttle, but it demonstrates that the U.S. can have a safe, reliable, and low-cost space system. The Taurus LMS is a short mission duration spacecraft designed to place one man into low Earth orbit (LEO). The driving factor for this design was the low payload carrying capabilities of the Taurus Booster - 1300 kg to a 300-km orbit. The Taurus LMS design is divided into six major design sections. The Human Factors section deals with the problems of life support and spacecraft cooling. The Propulsion section contains the Abort System, the Orbital Maneuvering System (OMS), the Reaction Control System (RCS), and Power Generation. The thermal protection systems and spacecraft structure are contained in the Structures section. The Avionics section includes Navigation, Attitude Determination, Data Processing, Communication systems, and Sensors. The Mission Analysis section was responsible for ground processing and spacecraft astrodynamics. The Systems Integration Section pulled the above sections together into one spacecraft, and addressed costing and reliability.

Genomic profiling of pelvic genital type leiomyosarcoma in a woman with a germline CHEK2:c.1100delC mutation and a concomitant diagnosis of metastatic invasive ductal breast carcinoma

PubMed Central

Reisle, Caralyn; Martin, Lee Ann; Alwelaie, Yazeed; Mungall, Karen L.; Ch'ng, Carolyn; Thomas, Ruth; Ng, Tony; Yip, Stephen; J. Lim, Howard; Sun, Sophie; Young, Sean S.; Karsan, Aly; Zhao, Yongjun; Mungall, Andrew J.; Moore, Richard A.; J. Renouf, Daniel; Gelmon, Karen; Ma, Yussanne P.; Hayes, Malcolm; Laskin, Janessa; Marra, Marco A.; Schrader, Kasmintan A.; Jones, Steven J. M.

2017-01-01

We describe a woman with the known pathogenic germline variant CHEK2:c.1100delC and synchronous diagnoses of both pelvic genital type leiomyosarcoma (LMS) and metastatic invasive ductal breast carcinoma. CHEK2 (checkpoint kinase 2) is a tumor-suppressor gene encoding a serine/threonine-protein kinase (CHEK2) involved in double-strand DNA break repair and cell cycle arrest. The CHEK2:c.1100delC variant is a moderate penetrance allele resulting in an approximately twofold increase in breast cancer risk. Whole-genome and whole-transcriptome sequencing were performed on the leiomyosarcoma and matched blood-derived DNA. Despite the presence of several genomic hits within the double-strand DNA damage pathway (CHEK2 germline variant and multiple RAD51B somatic structural variants), tumor profiling did not show an obvious DNA repair deficiency signature. However, even though the LMS displayed clear malignant features, its genomic profiling revealed several characteristics classically associated with leiomyomas including a translocation, t(12;14), with one breakpoint disrupting RAD51B and the other breakpoint upstream of HMGA2 with very high expression of HMGA2 and PLAG1. This is the first report of LMS genomic profiling in a patient with the germline CHEK2:c.1100delC variant and an additional diagnosis of metastatic invasive ductal breast carcinoma. We also describe a possible mechanistic relationship between leiomyoma and LMS based on genomic and transcriptome data. Our findings suggest that RAD51B translocation and HMGA2 overexpression may play an important role in LMS oncogenesis. PMID:28514723

Genomic profiling of pelvic genital type leiomyosarcoma in a woman with a germline CHEK2:c.1100delC mutation and a concomitant diagnosis of metastatic invasive ductal breast carcinoma.

PubMed

Thibodeau, My Linh; Reisle, Caralyn; Zhao, Eric; Martin, Lee Ann; Alwelaie, Yazeed; Mungall, Karen L; Ch'ng, Carolyn; Thomas, Ruth; Ng, Tony; Yip, Stephen; J Lim, Howard; Sun, Sophie; Young, Sean S; Karsan, Aly; Zhao, Yongjun; Mungall, Andrew J; Moore, Richard A; J Renouf, Daniel; Gelmon, Karen; Ma, Yussanne P; Hayes, Malcolm; Laskin, Janessa; Marra, Marco A; Schrader, Kasmintan A; Jones, Steven J M

2017-09-01

We describe a woman with the known pathogenic germline variant CHEK2 :c.1100delC and synchronous diagnoses of both pelvic genital type leiomyosarcoma (LMS) and metastatic invasive ductal breast carcinoma. CHEK2 (checkpoint kinase 2) is a tumor-suppressor gene encoding a serine/threonine-protein kinase (CHEK2) involved in double-strand DNA break repair and cell cycle arrest. The CHEK2 :c.1100delC variant is a moderate penetrance allele resulting in an approximately twofold increase in breast cancer risk. Whole-genome and whole-transcriptome sequencing were performed on the leiomyosarcoma and matched blood-derived DNA. Despite the presence of several genomic hits within the double-strand DNA damage pathway ( CHEK2 germline variant and multiple RAD51B somatic structural variants), tumor profiling did not show an obvious DNA repair deficiency signature. However, even though the LMS displayed clear malignant features, its genomic profiling revealed several characteristics classically associated with leiomyomas including a translocation, t(12;14), with one breakpoint disrupting RAD51B and the other breakpoint upstream of HMGA2 with very high expression of HMGA2 and PLAG1 This is the first report of LMS genomic profiling in a patient with the germline CHEK2 :c.1100delC variant and an additional diagnosis of metastatic invasive ductal breast carcinoma. We also describe a possible mechanistic relationship between leiomyoma and LMS based on genomic and transcriptome data. Our findings suggest that RAD51B translocation and HMGA2 overexpression may play an important role in LMS oncogenesis. © 2017 Thibodeau et al.; Published by Cold Spring Harbor Laboratory Press.

Evaluating lipid mediator structural complexity using ion mobility spectrometry combined with mass spectrometry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kyle, Jennifer E.; Aly, Noor; Zheng, Xueyun

Lipid mediators (LMs) are broadly defined as a class of bioactive lipophilic molecules that regulate cell-to-cell communication events with many having a strong correlation with various human diseases and conditions. LMs are usually analyzed with liquid chromatography and mass spectrometry (LC-MS), but their numerous isomers greatly complicate the measurements with essentially identical fragmentation spectra and LC separations not always sufficient for distinguishing the features. In this work, we characterized LMs having specific categories using ion mobility spectrometry coupled with mass spectrometry (IMS-MS). The IMS collision cross sections and MS m/z values displayed distinct trends for each LM category studied. LC-IMS-MSmore » analyses on flu infected mouse tissue samples also illustrated the presence of additional LM species not in our databases.« less

Gain-of-function mutations in the phosphatidylserine synthase 1 (PTDSS1) gene cause Lenz-Majewski syndrome.

PubMed

Sousa, Sérgio B; Jenkins, Dagan; Chanudet, Estelle; Tasseva, Guergana; Ishida, Miho; Anderson, Glenn; Docker, James; Ryten, Mina; Sa, Joaquim; Saraiva, Jorge M; Barnicoat, Angela; Scott, Richard; Calder, Alistair; Wattanasirichaigoon, Duangrurdee; Chrzanowska, Krystyna; Simandlová, Martina; Van Maldergem, Lionel; Stanier, Philip; Beales, Philip L; Vance, Jean E; Moore, Gudrun E

2014-01-01

Lenz-Majewski syndrome (LMS) is a syndrome of intellectual disability and multiple congenital anomalies that features generalized craniotubular hyperostosis. By using whole-exome sequencing and selecting variants consistent with the predicted dominant de novo etiology of LMS, we identified causative heterozygous missense mutations in PTDSS1, which encodes phosphatidylserine synthase 1 (PSS1). PSS1 is one of two enzymes involved in the production of phosphatidylserine. Phosphatidylserine synthesis was increased in intact fibroblasts from affected individuals, and end-product inhibition of PSS1 by phosphatidylserine was markedly reduced. Therefore, these mutations cause a gain-of-function effect associated with regulatory dysfunction of PSS1. We have identified LMS as the first human disease, to our knowledge, caused by disrupted phosphatidylserine metabolism. Our results point to an unexplored link between phosphatidylserine synthesis and bone metabolism.

Investigation of Diesel’s Residual Noise on Predictive Vehicles Noise Cancelling using LMS Adaptive Algorithm

NASA Astrophysics Data System (ADS)

Arttini Dwi Prasetyowati, Sri; Susanto, Adhi; Widihastuti, Ida

2017-04-01

Every noise problems require different solution. In this research, the noise that must be cancelled comes from roadway. Least Mean Square (LMS) adaptive is one of the algorithm that can be used to cancel that noise. Residual noise always appears and could not be erased completely. This research aims to know the characteristic of residual noise from vehicle’s noise and analysis so that it is no longer appearing as a problem. LMS algorithm was used to predict the vehicle’s noise and minimize the error. The distribution of the residual noise could be observed to determine the specificity of the residual noise. The statistic of the residual noise close to normal distribution with = 0,0435, = 1,13 and the autocorrelation of the residual noise forming impulse. As a conclusion the residual noise is insignificant.

A Two-Stage Approach for Improving the Convergence of Least-Mean-Square Adaptive Decision-Feedback Equalizers in the Presence of Severe Narrowband Interference

NASA Astrophysics Data System (ADS)

Batra, Arun; Zeidler, James R.; Beex, A. A. Louis

2007-12-01

It has previously been shown that a least-mean-square (LMS) decision-feedback filter can mitigate the effect of narrowband interference (L.-M. Li and L. Milstein, 1983). An adaptive implementation of the filter was shown to converge relatively quickly for mild interference. It is shown here, however, that in the case of severe narrowband interference, the LMS decision-feedback equalizer (DFE) requires a very large number of training symbols for convergence, making it unsuitable for some types of communication systems. This paper investigates the introduction of an LMS prediction-error filter (PEF) as a prefilter to the equalizer and demonstrates that it reduces the convergence time of the two-stage system by as much as two orders of magnitude. It is also shown that the steady-state bit-error rate (BER) performance of the proposed system is still approximately equal to that attained in steady-state by the LMS DFE-only. Finally, it is shown that the two-stage system can be implemented without the use of training symbols. This two-stage structure lowers the complexity of the overall system by reducing the number of filter taps that need to be adapted, while incurring a slight loss in the steady-state BER.

Efficient block processing of long duration biotelemetric brain data for health care monitoring

DOE Office of Scientific and Technical Information (OSTI.GOV)

Soumya, I.; Zia Ur Rahman, M., E-mail: mdzr-5@ieee.org; Rama Koti Reddy, D. V.

In real time clinical environment, the brain signals which doctor need to analyze are usually very long. Such a scenario can be made simple by partitioning the input signal into several blocks and applying signal conditioning. This paper presents various block based adaptive filter structures for obtaining high resolution electroencephalogram (EEG) signals, which estimate the deterministic components of the EEG signal by removing noise. To process these long duration signals, we propose Time domain Block Least Mean Square (TDBLMS) algorithm for brain signal enhancement. In order to improve filtering capability, we introduce normalization in the weight update recursion of TDBLMS,more » which results TD-B-normalized-least mean square (LMS). To increase accuracy and resolution in the proposed noise cancelers, we implement the time domain cancelers in frequency domain which results frequency domain TDBLMS and FD-B-Normalized-LMS. Finally, we have applied these algorithms on real EEG signals obtained from human using Emotive Epoc EEG recorder and compared their performance with the conventional LMS algorithm. The results show that the performance of the block based algorithms is superior to the LMS counter-parts in terms of signal to noise ratio, convergence rate, excess mean square error, misadjustment, and coherence.« less

Giant Extraluminal Leiomyoma of the Colon: Rare Cause of Symptomatic Pelvic Mass

PubMed Central

Sagnotta, Andrea; Sparagna, Alessandra; Uccini, Stefania; Mercantini, Paolo

2015-01-01

Leiomyomas (LMs) may appear throughout the entire gastrointestinal tract but are rarely seen in the colon-rectum and only 5 of those measured greater than 15 cm in diameter. Pain and palpable abdominal mass are the most common symptoms. Surgical resection is the treatment of choice for most LMs. We here describe a case of a 46-year-old woman who presented with a 3-month history of abdominal pain associated with worsening constipation and abdominal distension. A pelvic solid, polylobulate, left-sided mass was noted on examination. Preoperative findings revealed a dishomogeneous sigmoid mass with calcified spots compressing small intestine and bladder. At laparotomy, a large polylobulate and well-circumscribed mass arising from the descending colon mesentery and displacing small intestine, uterus, and ovaries. A segmental colon resection was performed. An extraluminal 18- × 12- × 5-cm paucicellular sigmoid colon leiomyoma was histologically diagnosed. Our case is one of the few giant (>15 cm) sigmoid colon LMs reported in the literature. Although rare and benign in nature, LMs of the colon can cause life-threatening complications that could require emergency treatment and they should be included in the differential diagnosis of large abdominopelvic masses. Follow-up after surgery is necessary for tumors with any atypia or mitotic activity. PMID:26011198

Giant extraluminal leiomyoma of the colon: rare cause of symptomatic pelvic mass.

PubMed

Sagnotta, Andrea; Sparagna, Alessandra; Uccini, Stefania; Mercantini, Paolo

2015-05-01

Leiomyomas (LMs) may appear throughout the entire gastrointestinal tract but are rarely seen in the colon-rectum and only 5 of those measured greater than 15 cm in diameter. Pain and palpable abdominal mass are the most common symptoms. Surgical resection is the treatment of choice for most LMs. We here describe a case of a 46-year-old woman who presented with a 3-month history of abdominal pain associated with worsening constipation and abdominal distension. A pelvic solid, polylobulate, left-sided mass was noted on examination. Preoperative findings revealed a dishomogeneous sigmoid mass with calcified spots compressing small intestine and bladder. At laparotomy, a large polylobulate and well-circumscribed mass arising from the descending colon mesentery and displacing small intestine, uterus, and ovaries. A segmental colon resection was performed. An extraluminal 18- × 12- × 5-cm paucicellular sigmoid colon leiomyoma was histologically diagnosed. Our case is one of the few giant (>15 cm) sigmoid colon LMs reported in the literature. Although rare and benign in nature, LMs of the colon can cause life-threatening complications that could require emergency treatment and they should be included in the differential diagnosis of large abdominopelvic masses. Follow-up after surgery is necessary for tumors with any atypia or mitotic activity.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Dick; Tsosie, Bernadette

Groundwater samples were collected from monitoring wells at the Bluewater, New Mexico, Disposal Site to monitor groundwater contaminants as specified in the 1997 Long-Term Surveillance Plan for the DOE Bluewater (UMTRCA Title II) Disposal Site Near Grants, New Mexico (LTSP). Sampling and analyses were conducted as specified in the Sampling and Analysis Plan for U.S. Department of Energy Office of Legacy Management Sites (LMS/PRO/S04351, continually updated). Duplicate samples were collected from locations 14(SG) and 21(M). Sampling originally scheduled for the week of May 11, 2015 was interrupted by heavy rainfall and later completed in June.

Application of Least Mean Square Algorithms to Spacecraft Vibration Compensation

NASA Technical Reports Server (NTRS)

Woodard , Stanley E.; Nagchaudhuri, Abhijit

1998-01-01

This paper describes the application of the Least Mean Square (LMS) algorithm in tandem with the Filtered-X Least Mean Square algorithm for controlling a science instrument's line-of-sight pointing. Pointing error is caused by a periodic disturbance and spacecraft vibration. A least mean square algorithm is used on-orbit to produce the transfer function between the instrument's servo-mechanism and error sensor. The result is a set of adaptive transversal filter weights tuned to the transfer function. The Filtered-X LMS algorithm, which is an extension of the LMS, tunes a set of transversal filter weights to the transfer function between the disturbance source and the servo-mechanism's actuation signal. The servo-mechanism's resulting actuation counters the disturbance response and thus maintains accurate science instrumental pointing. A simulation model of the Upper Atmosphere Research Satellite is used to demonstrate the algorithms.

Timescales of transport from the troposphere into the lowermost stratosphere

NASA Astrophysics Data System (ADS)

Boenisch, Harald; Hoor, Peter; Wernli, Heini

2010-05-01

The lowermost stratosphere (LMS) as part of the extratropical UTLS can be divided into dynamically and chemically distinct regions. A layer of mixed tropospheric and stratospheric tracer characteristics in the proximity of the extratropical tropopause: the extratropical tropopause transition layer (ExTL). This chemically distinct layer roughly coincides with a layer of strongly enhanced thermal stratification: the tropopause inversion layer (TIL) (Birner, 2006). The LMS above the ExTL, also named the free LMS (Bönisch et al., 2009), is less coupled to the local extratropical troposphere. Simultaneous in-situ measurements of CO2 and SF6 have been used to calculate mean transport time from the troposphere to the measurement location in the free LMS (Bönisch et al., 2009) which is on the order of months. In this study, we will use backward trajectories driven by operational ECMWF analyses wind fields to investigate the TST timescales into the LMS using the LAGRANTO scheme (Wernli and Davies, 1997). We applied a statistical data set of trajectories, which were initialized on isentropes above the 2 PVU surface up to 450K and calculated backward over 270 days (9 month) for our analysis. The results will be compared with the results from mass balance studies based on in-situ observations (Hoor et al., 2005; Bönisch et al., 2009). Furthermore, a focus is on the role of timescales of TIL formation in the LMS. Birner, T.: Fine-scale structure of the extratropical tropopause region, Journal of Geophysical Research-Atmospheres, 111, Doi 10.1029/2005jd006301, 2006. Bönisch, H., Engel, A., Curtius, J., Birner, T., and Hoor, P.: Quantifying transport into the lowermost stratosphere using simultaneous in-situ measurements of sf6 and co2, Atmospheric Chemistry and Physics, 9, 5905-5919, 2009. Hoor, P., Gurk, C., Brunner, D., Hegglin, M. I., Wernli, H., and Fischer, H.: Seasonality and extent of extratropical tst derived from in-situ co measurements during spurt, Atmospheric Chemistry and Physics, 4, 1427-1442, 2004. Hoor, P., Fischer, H., and Lelieveld, J.: Tropical and extratropical tropospheric air in the lowermost stratosphere over europe: A co-based budget, Geophysical Research Letters, 32, Doi 10.1029/2004gl022018, 2005. Wernli, H., and Davies, H. C.: A lagrangian-based analysis of extratropical cyclones .1. The method and some applications, Quarterly Journal of the Royal Meteorological Society, 123, 467-489, 1997.

Validating a Web-based Diabetes Education Program in continuing nursing education: knowledge and competency change and user perceptions on usability and quality

PubMed Central

2014-01-01

Background Nurses as the members of health care professionals need to improve their knowledge and competencies particularly in diabetes mellitus through continuing nursing education programs. E-learning is an indirect method of training that can meet nurses’ educational needs. This study is aimed at validating a web-based diabetes education program through measurement of nurses’ knowledge and clinical competency in diabetes and nurses’ perception about its usability and quality. Methods This Quasi-experimental research was conducted on a single group of 31 nurses employed in hospitals affiliated with Shiraz University of Medical Sciences. We used a 125 MCQ knowledge test and Objective Structured Clinical Exam (OSCE) to measure knowledge and clinical competency of nurses in diabetes before and after intervention. A Learning Management System (LMS) was designed to provide educational content in the form of 12 multimedia electronic modules, interactive tests; a forum and learning activities. Nurses were trained for two months in this system after which the post-test was administered. Each nurse completed two questionnaires for measurement of their perceptions on usability and quality. We used descriptive statistics for demographic and descriptive data analysis. Paired t-test was used to compare pre- and post-data using SPSS. Results The findings showed significant differences in knowledge scores (p < 0.001), total score of clinical competencies (p < 0.001), and all ten assessed clinical competencies. The range of ratings given by participants varied on the six usability variables of Web-based training (2.96-4.23 from 5) and eight quality variables of Web-based training (3.58-4.37 from 5). Conclusion Web-based education increased nurses’ knowledge and competencies in diabetes. They positively evaluated Web-based learning usability and quality. It is hoped that this course will have a positive clinical outcomes. PMID:26086025

Validating a Web-based Diabetes Education Program in continuing nursing education: knowledge and competency change and user perceptions on usability and quality.

PubMed

Moattari, Marzieh; Moosavinasab, Elham; Dabbaghmanesh, Mohammad Hossein; ZarifSanaiey, Nahid

2014-01-01

Nurses as the members of health care professionals need to improve their knowledge and competencies particularly in diabetes mellitus through continuing nursing education programs. E-learning is an indirect method of training that can meet nurses' educational needs. This study is aimed at validating a web-based diabetes education program through measurement of nurses' knowledge and clinical competency in diabetes and nurses' perception about its usability and quality. This Quasi-experimental research was conducted on a single group of 31 nurses employed in hospitals affiliated with Shiraz University of Medical Sciences. We used a 125 MCQ knowledge test and Objective Structured Clinical Exam (OSCE) to measure knowledge and clinical competency of nurses in diabetes before and after intervention. A Learning Management System (LMS) was designed to provide educational content in the form of 12 multimedia electronic modules, interactive tests; a forum and learning activities. Nurses were trained for two months in this system after which the post-test was administered. Each nurse completed two questionnaires for measurement of their perceptions on usability and quality. We used descriptive statistics for demographic and descriptive data analysis. Paired t-test was used to compare pre- and post-data using SPSS. The findings showed significant differences in knowledge scores (p < 0.001), total score of clinical competencies (p < 0.001), and all ten assessed clinical competencies. The range of ratings given by participants varied on the six usability variables of Web-based training (2.96-4.23 from 5) and eight quality variables of Web-based training (3.58-4.37 from 5). Web-based education increased nurses' knowledge and competencies in diabetes. They positively evaluated Web-based learning usability and quality. It is hoped that this course will have a positive clinical outcomes.

Role of the Library Media Specialist in Greening the Curriculum: A Community-Based Approach to Teaching 21st Century Skills outside of the School Library through the Practice of Urban Agriculture

ERIC Educational Resources Information Center

Torrise, Michelle L.

2010-01-01

Some of the author's most valuable experiences as a library media specialist (LMS) were not in a school library. Rather, they were on the streets of Chicago, in community gardens, and on the rooftops of buildings in Humboldt Park, where she was hired by the University of Illinois Community Informatics Initiative as a graduate assistant and LMS in…

Tuning the Composition and Nanostructure of Pt/Ir Films via Anodized Aluminum Oxide Templated Atomic Layer Deposition

DTIC Science & Technology

2010-01-01

12 ] to dictate fi lm morphology. Such templated deposition is typically con- ducted by either electrodeposition or elec- troless deposition, with...non-enzymatic glucose sensing. [ 34–36 ] In particular, the syn- thesis of such nanostructured fi lms is delineated with a focus on the precise...deposited using alternating exposures to trimethylaluminum and H 2 O to provide a uniform nucleation layer for Pt and Ir fi lms. Nanostructured Pt fi

An approach to effective UHF (S/L band) data communications for satellite Personal Communication Service (PCS)

NASA Technical Reports Server (NTRS)

Hayase, Joshua Y.

1995-01-01

Reliable signaling information transfer is fundamental in supporting the needs of data communication PCS via LMS (Land Mobile Service) SSs (satellite systems). The needs of the system designer can be satisfied only through the collection of media information that can be brought to bear on the pertinent design issues. We at ISI hope to continue our dialogue with fading media experts to address the unique data communications needs of PCS via LMS SSs.

May 2013 Groundwater and Surface Water Sampling at the Rio Blanco, Colorado, Site (Data Validation Package)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hutton, Rick

2013-10-01

Annual sampling was conducted at the Rio Blanco, Colorado, site for the Long-Term Hydrologic Monitoring Program May 14-16, 2013, to monitor groundwater and surface water for potential radionuclide contamination. Sampling and analyses were conducted as specified in Sampling and Analysis Plan for the U.S. Department of Energy Office of Legacy Management Sites (LMS/PRO/S04351, continually updated). A duplicate sample was collected from location CER #1 Black Sulphur. Samples were analyzed for gamma-emitting radionuclides by high-resolution gamma spectrometry and for tritium using the conventional and enrichment methods.

Efficacy of fenbendazole and levamisole treatments in captive Houston toads (Bufo [Anaxyrus] houstonensis).

PubMed

Bianchi, Catherine M; Johnson, Cassidy B; Howard, Lauren L; Crump, Paul

2014-09-01

Effective disease monitoring and prevention is critical to the success of captive amphibian care. Nematodes, including the genera Rhabdias and Strongyloides, are known to contribute to mortality in captive amphibians and have been identified in the Houston Zoo's endangered Houston toad (Bufo [Anaxyrus] houstonensis) captive assurance colony. Five years of fecal data for the toad colony were compiled and analyzed in order to investigate the efficacy of two anthelminthic medications, fenbendazole (FBZ) and levamisole (LMS), which were used to control nematode infections. Both FBZ (dusted onto food items) and topical LMS (6.5 to 13.5 mg/kg) significantly reduced the number of nematode eggs, larvae, and adults observed by fecal parasitologic examination. There were no significant differences between treatments, and egg reappearance periods were difficult to compare as a result of low sample size. No adverse effects from either anthelminthic treatment were observed. Both topical LMS and oral FBZ appear to be safe and efficacious treatments for the reduction of the internal nematode burden in captive Houston toads.

Design of adaptive control systems by means of self-adjusting transversal filters

NASA Technical Reports Server (NTRS)

Merhav, S. J.

1986-01-01

The design of closed-loop adaptive control systems based on nonparametric identification was addressed. Implementation is by self-adjusting Least Mean Square (LMS) transversal filters. The design concept is Model Reference Adaptive Control (MRAC). Major issues are to preserve the linearity of the error equations of each LMS filter, and to prevent estimation bias that is due to process or measurement noise, thus providing necessary conditions for the convergence and stability of the control system. The controlled element is assumed to be asymptotically stable and minimum phase. Because of the nonparametric Finite Impulse Response (FIR) estimates provided by the LMS filters, a-priori information on the plant model is needed only in broad terms. Following a survey of control system configurations and filter design considerations, system implementation is shown here in Single Input Single Output (SISO) format which is readily extendable to multivariable forms. In extensive computer simulation studies the controlled element is represented by a second-order system with widely varying damping, natural frequency, and relative degree.

Global coverage Mobile Satellite Systems: System availability versus channel propagation impairments

NASA Technical Reports Server (NTRS)

Sforza, M.; Buonomo, S.; Poiaresbaptista, J. P. V.

1993-01-01

Mobile Satellite Systems (MSS) in Highly Elliptical (HEO) and circular Earth orbits at Medium (MEO) and Low (LEO) altitudes have been intensively studied in the last few years as an effective means of providing global communication services. Such global coverage MSS networks are also expected to mitigate typical channel impairments usually encountered in geostationary Land Mobile Satellite (LMS) systems. In the design stages of these satellite networks, information regarding the mobile propagation channel is needed to assess the overall link availability versus elevation angle and environmental scenarios. For multisatellite LMS configurations, the mobile user on the Earth surface sees, at any given time, more than one satellite of the constellation. In our paper, it is shown that, under certain working assumptions regarding the statistics of the propagation channel, an improvement of the link availability may be achieved through the use of a multisatellite constellation. The analyses have been carried out using the European Space Agency (ESA) LMS propagation data base which presently covers a wide range of elevation angles and environmental scenarios.

The co-existence of transcriptional activator and transcriptional repressor MEF2 complexes influences tumor aggressiveness

PubMed Central

Di Giorgio, Eros; Franforte, Elisa; Cefalù, Sebastiano; Rossi, Sabrina; Dei Tos, Angelo Paolo; Polano, Maurizio; Maestro, Roberta; Paluvai, Harikrishnareddy

2017-01-01

The contribution of MEF2 TFs to the tumorigenic process is still mysterious. Here we clarify that MEF2 can support both pro-oncogenic or tumor suppressive activities depending on the interaction with co-activators or co-repressors partners. Through these interactions MEF2 supervise histone modifications associated with gene activation/repression, such as H3K4 methylation and H3K27 acetylation. Critical switches for the generation of a MEF2 repressive environment are class IIa HDACs. In leiomyosarcomas (LMS), this two-faced trait of MEF2 is relevant for tumor aggressiveness. Class IIa HDACs are overexpressed in 22% of LMS, where high levels of MEF2, HDAC4 and HDAC9 inversely correlate with overall survival. The knock out of HDAC9 suppresses the transformed phenotype of LMS cells, by restoring the transcriptional proficiency of some MEF2-target loci. HDAC9 coordinates also the demethylation of H3K4me3 at the promoters of MEF2-target genes. Moreover, we show that class IIa HDACs do not bind all the regulative elements bound by MEF2. Hence, in a cell MEF2-target genes actively transcribed and strongly repressed can coexist. However, these repressed MEF2-targets are poised in terms of chromatin signature. Overall our results candidate class IIa HDACs and HDAC9 in particular, as druggable targets for a therapeutic intervention in LMS. PMID:28419090

Critique and sensitivity analysis of the compensation function used in the LMS Hudson River striped bass models. Environmental Sciences Division publication No. 944

DOE Office of Scientific and Technical Information (OSTI.GOV)

Van Winkle, W.; Christensen, S.W.; Kauffman, G.

1976-12-01

The description and justification for the compensation function developed and used by Lawler, Matusky and Skelly Engineers (LMS) (under contract to Consolidated Edison Company of New York) in their Hudson River striped bass models are presented. A sensitivity analysis of this compensation function is reported, based on computer runs with a modified version of the LMS completely mixed (spatially homogeneous) model. Two types of sensitivity analysis were performed: a parametric study involving at least five levels for each of the three parameters in the compensation function, and a study of the form of the compensation function itself, involving comparison ofmore » the LMS function with functions having no compensation at standing crops either less than or greater than the equilibrium standing crops. For the range of parameter values used in this study, estimates of percent reduction are least sensitive to changes in YS, the equilibrium standing crop, and most sensitive to changes in KXO, the minimum mortality rate coefficient. Eliminating compensation at standing crops either less than or greater than the equilibrium standing crops results in higher estimates of percent reduction. For all values of KXO and for values of YS and KX at and above the baseline values, eliminating compensation at standing crops less than the equilibrium standing crops results in a greater increase in percent reduction than eliminating compensation at standing crops greater than the equilibrium standing crops.« less

Resistive edge mode instability in stellarator and tokamak geometries

NASA Astrophysics Data System (ADS)

Mahmood, M. Ansar; Rafiq, T.; Persson, M.; Weiland, J.

2008-09-01

Geometrical effects on linear stability of electrostatic resistive edge modes are investigated in the three-dimensional Wendelstein 7-X stellarator [G. Grieger et al., Plasma Physics and Controlled Nuclear Fusion Research 1990 (International Atomic Energy Agency, Vienna, 1991), Vol. 3, p. 525] and the International Thermonuclear Experimental Reactor [Progress in the ITER Physics Basis, Nucl. Fusion 7, S1, S285 (2007)]-like equilibria. An advanced fluid model is used for the ions together with the reduced Braghinskii equations for the electrons. Using the ballooning mode representation, the drift wave problem is set as an eigenvalue equation along a field line and is solved numerically using a standard shooting technique. A significantly larger magnetic shear and a less unfavorable normal curvature in the tokamak equilibrium are found to give a stronger finite-Larmor radius stabilization and a more narrow mode spectrum than in the stellarator. The effect of negative global magnetic shear in the tokamak is found to be stabilizing. The growth rate on a tokamak magnetic flux surface is found to be comparable to that on a stellarator surface with the same global magnetic shear but the eigenfunction in the tokamak is broader than in the stellarator due to the presence of large negative local magnetic shear (LMS) on the tokamak surface. A large absolute value of the LMS in a region of unfavorable normal curvature is found to be stabilizing in the stellarator, while in the tokamak case, negative LMS is found to be stabilizing and positive LMS destabilizing.

Assessment of the efficacy of blended learning in an introductory pharmacy class

NASA Astrophysics Data System (ADS)

Munson, Christina Elizabeth

Blended learning is the convergence between traditional face-to-face learning typically seen in a university setting and a computer-mediated learning environment, and is increasingly being seen as a viable alternative for learning instruction. Pharmaceutical calculations (PC) is a course taken by students in the first year in the school of pharmacy at the University of Kansas (KU SOP). One of the objectives of the PC class is that students are able to perform calculations with minimal error consistently. This requires repetitive drill which is a poor use of class time. By moving presentation of material online and using class time for small learning group problem solving as well as practice exams, the transformation of the course to a blended or hybrid course is assessed for efficacy and found to have student outcomes which are comparable to previous face-to-face (F2F) classes. As KU SOP expands it class sizes from 105 to ˜150 students and its campuses (building a satellite campus in Wichita, Kansas), being able to provide quality instruction at a reasonable cost is desirable. By redesigning PC to be a hybrid course, the need to hire additional instructors and/or increase available resources is minimized. Instructors remain for the large part on the main campus in Lawrence while students are learning at remote locations, a cost-effective measure for all parties involved. Using small learning groups (consisting of not more than 3 or 4 students) to work problems in PC was demonstrated to be an effective use of F2F class time in the fall semester, 2008 at KU. The class was taught by the same instructor in the fall of 2009 using blended learning as the class format. The current computer Learning Management System (LMS) in use at KU is Blackboard((c)2010). By using Blackboard to deliver lectures and have students work through tutorials to learn the material, class time was devoted to highly-focused problem solving. Due to unequal data distribution, the non-parametric tests Kruskal-Wallis and Mann-Whitney were used to assess student outcomes from three different classes (years) of students. The only significant differences were between groups of males in two different face-to-face classes. There was no significant difference between BL and F2F class formats. In general, blended learning was found to be as effective as a traditional F2F class format when comparing final student outcomes.

OARE STS-78 (LMS-1) Final Report

NASA Technical Reports Server (NTRS)

Rice, James E.

1996-01-01

The report is organized into sections representing the phases of work performed in analyzing the STS-78 (LMS-1) results. Section 1 briefly outlines the Orbital Acceleration Research Experiment (OARE) system features, coordinates, and measurement parameters. Section 2 describes the results from STS-78. The mission description, data calibration, and representative data obtained on STS-78 are presented. Also, the anomalous performance of OARE on STS-78 is discussed. Finally, Section 3 presents a discussion of accuracy achieved and achievable with OARE. Appendix A discusses the data processing methodology in detail.

Educational Technologies in Problem-Based Learning in Health Sciences Education: A Systematic Review

PubMed Central

Jin, Jun

2014-01-01

Background As a modern pedagogical philosophy, problem-based learning (PBL) is increasingly being recognized as a major research area in student learning and pedagogical innovation in health sciences education. A new area of research interest has been the role of emerging educational technologies in PBL. Although this field is growing, no systematic reviews of studies of the usage and effects of educational technologies in PBL in health sciences education have been conducted to date. Objective The aim of this paper is to review new and emerging educational technologies in problem-based curricula, with a specific focus on 3 cognate clinical disciplines: medicine, dentistry, and speech and hearing sciences. Analysis of the studies reviewed focused on the effects of educational technologies in PBL contexts while addressing the particular issue of scaffolding of student learning. Methods A comprehensive computerized database search of full-text articles published in English from 1996 to 2014 was carried out using 3 databases: ProQuest, Scopus, and EBSCOhost. Eligibility criteria for selection of studies for review were also determined in light of the population, intervention, comparison, and outcomes (PICO) guidelines. The population was limited to postsecondary education, specifically in dentistry, medicine, and speech and hearing sciences, in which PBL was the key educational pedagogy and curriculum design. Three types of educational technologies were identified as interventions used to support student inquiry: learning software and digital learning objects; interactive whiteboards (IWBs) and plasma screens; and learning management systems (LMSs). Results Of 470 studies, 28 were selected for analysis. Most studies examined the effects of learning software and digital learning objects (n=20) with integration of IWB (n=5) and LMS (n=3) for PBL receiving relatively less attention. The educational technologies examined in these studies were seen as potentially fit for problem-based health sciences education. Positive outcomes for student learning included providing rich, authentic problems and/or case contexts for learning; supporting student development of medical expertise through the accessing and structuring of expert knowledge and skills; making disciplinary thinking and strategies explicit; providing a platform to elicit articulation, collaboration, and reflection; and reducing perceived cognitive load. Limitations included cumbersome scenarios, infrastructure requirements, and the need for staff and student support in light of the technological demands of new affordances. Conclusions This literature review demonstrates the generally positive effect of educational technologies in PBL. Further research into the various applications of educational technology in PBL curricula is needed to fully realize its potential to enhance problem-based approaches in health sciences education. PMID:25498126

Educational technologies in problem-based learning in health sciences education: a systematic review.

PubMed

Jin, Jun; Bridges, Susan M

2014-12-10

As a modern pedagogical philosophy, problem-based learning (PBL) is increasingly being recognized as a major research area in student learning and pedagogical innovation in health sciences education. A new area of research interest has been the role of emerging educational technologies in PBL. Although this field is growing, no systematic reviews of studies of the usage and effects of educational technologies in PBL in health sciences education have been conducted to date. The aim of this paper is to review new and emerging educational technologies in problem-based curricula, with a specific focus on 3 cognate clinical disciplines: medicine, dentistry, and speech and hearing sciences. Analysis of the studies reviewed focused on the effects of educational technologies in PBL contexts while addressing the particular issue of scaffolding of student learning. A comprehensive computerized database search of full-text articles published in English from 1996 to 2014 was carried out using 3 databases: ProQuest, Scopus, and EBSCOhost. Eligibility criteria for selection of studies for review were also determined in light of the population, intervention, comparison, and outcomes (PICO) guidelines. The population was limited to postsecondary education, specifically in dentistry, medicine, and speech and hearing sciences, in which PBL was the key educational pedagogy and curriculum design. Three types of educational technologies were identified as interventions used to support student inquiry: learning software and digital learning objects; interactive whiteboards (IWBs) and plasma screens; and learning management systems (LMSs). Of 470 studies, 28 were selected for analysis. Most studies examined the effects of learning software and digital learning objects (n=20) with integration of IWB (n=5) and LMS (n=3) for PBL receiving relatively less attention. The educational technologies examined in these studies were seen as potentially fit for problem-based health sciences education. Positive outcomes for student learning included providing rich, authentic problems and/or case contexts for learning; supporting student development of medical expertise through the accessing and structuring of expert knowledge and skills; making disciplinary thinking and strategies explicit; providing a platform to elicit articulation, collaboration, and reflection; and reducing perceived cognitive load. Limitations included cumbersome scenarios, infrastructure requirements, and the need for staff and student support in light of the technological demands of new affordances. This literature review demonstrates the generally positive effect of educational technologies in PBL. Further research into the various applications of educational technology in PBL curricula is needed to fully realize its potential to enhance problem-based approaches in health sciences education.

Fast convergent frequency-domain MIMO equalizer for few-mode fiber communication systems

NASA Astrophysics Data System (ADS)

He, Xuan; Weng, Yi; Wang, Junyi; Pan, Z.

2018-02-01

Space division multiplexing using few-mode fibers has been extensively explored to sustain the continuous traffic growth. In few-mode fiber optical systems, both spatial and polarization modes are exploited to transmit parallel channels, thus increasing the overall capacity. However, signals on spatial channels inevitably suffer from the intrinsic inter-modal coupling and large accumulated differential mode group delay (DMGD), which causes spatial modes de-multiplex even harder. Many research articles have demonstrated that frequency domain adaptive multi-input multi-output (MIMO) equalizer can effectively compensate the DMGD and demultiplex the spatial channels with digital signal processing (DSP). However, the large accumulated DMGD usually requires a large number of training blocks for the initial convergence of adaptive MIMO equalizers, which will decrease the overall system efficiency and even degrade the equalizer performance in fast-changing optical channels. Least mean square (LMS) algorithm is always used in MIMO equalization to dynamically demultiplex the spatial signals. We have proposed to use signal power spectral density (PSD) dependent method and noise PSD directed method to improve the convergence speed of adaptive frequency domain LMS algorithm. We also proposed frequency domain recursive least square (RLS) algorithm to further increase the convergence speed of MIMO equalizer at cost of greater hardware complexity. In this paper, we will compare the hardware complexity and convergence speed of signal PSD dependent and noise power directed algorithms against the conventional frequency domain LMS algorithm. In our numerical study of a three-mode 112 Gbit/s PDM-QPSK optical system with 3000 km transmission, the noise PSD directed and signal PSD dependent methods could improve the convergence speed by 48.3% and 36.1% respectively, at cost of 17.2% and 10.7% higher hardware complexity. We will also compare the frequency domain RLS algorithm against conventional frequency domain LMS algorithm. Our numerical study shows that, in a three-mode 224 Gbit/s PDM-16-QAM system with 3000 km transmission, the RLS algorithm could improve the convergence speed by 53.7% over conventional frequency domain LMS algorithm.

Doxycycline Sclerotherapy Is Superior in the Treatment of Pediatric Lymphatic Malformations.

PubMed

Thomas, Debi M; Wieck, Minna M; Grant, Christa N; Dossa, Avafia; Nowicki, Donna; Stanley, Phillip; Zeinati, Chadi; Howell, Lori K; Anselmo, Dean M

2016-12-01

To evaluate efficacy of sclerotherapy with doxycycline versus sodium tetradecyl sulfate (STS) for treatment of macrocystic and mixed lymphatic malformations (LMs). This single-center retrospective review identified 41 children (17 boys; 24 girls; age range, 1 month to 15.4 y) who underwent sclerotherapy with doxycycline (n = 32) or STS (n = 9) for macrocystic (n = 31) or mixed (n = 10) LMs. There were 114 treatments performed, averaging 2.8 treatments (range, 1-8 treatments) per patient. Average follow-up time was 10 months (range, 1-59 months). Clinical response was deemed excellent or moderate if > 90% or > 50% of LMs resolved based on visual estimate. With doxycycline, 87% of patients (28 of 32) had excellent or moderate response with an average of 2.8 treatments (range, 1-7 treatments); 13% required subsequent resection. With 3% STS monotherapy, only 55% of patients (5 of 9) had excellent or moderate response with an average of 2.8 treatments (range, 1-8 treatments), and 33% required subsequent resection. Significantly fewer patients treated with STS responded well compared with patients treated with doxycycline (P = .03). Patients treated with STS had significantly longer follow-up than patients treated with doxycycline (27 months vs 6 months, P = .0001). Doxycycline monotherapy resulted in a high rate of excellent clinical outcomes after a few treatments without increased need for subsequent operative resection. These results support use of doxycycline sclerotherapy as primary treatment for macrocystic and mixed LMs in children. Copyright © 2016 SIR. Published by Elsevier Inc. All rights reserved.

Least median of squares and iteratively re-weighted least squares as robust linear regression methods for fluorimetric determination of α-lipoic acid in capsules in ideal and non-ideal cases of linearity.

PubMed

Korany, Mohamed A; Gazy, Azza A; Khamis, Essam F; Ragab, Marwa A A; Kamal, Miranda F

2018-06-01

This study outlines two robust regression approaches, namely least median of squares (LMS) and iteratively re-weighted least squares (IRLS) to investigate their application in instrument analysis of nutraceuticals (that is, fluorescence quenching of merbromin reagent upon lipoic acid addition). These robust regression methods were used to calculate calibration data from the fluorescence quenching reaction (∆F and F-ratio) under ideal or non-ideal linearity conditions. For each condition, data were treated using three regression fittings: Ordinary Least Squares (OLS), LMS and IRLS. Assessment of linearity, limits of detection (LOD) and quantitation (LOQ), accuracy and precision were carefully studied for each condition. LMS and IRLS regression line fittings showed significant improvement in correlation coefficients and all regression parameters for both methods and both conditions. In the ideal linearity condition, the intercept and slope changed insignificantly, but a dramatic change was observed for the non-ideal condition and linearity intercept. Under both linearity conditions, LOD and LOQ values after the robust regression line fitting of data were lower than those obtained before data treatment. The results obtained after statistical treatment indicated that the linearity ranges for drug determination could be expanded to lower limits of quantitation by enhancing the regression equation parameters after data treatment. Analysis results for lipoic acid in capsules, using both fluorimetric methods, treated by parametric OLS and after treatment by robust LMS and IRLS were compared for both linearity conditions. Copyright © 2018 John Wiley & Sons, Ltd.

Growth reference for Saudi preschool children: LMS parameters and percentiles.

PubMed

Shaik, Shaffi Ahamed; El Mouzan, Mohammad Issa; AlSalloum, Abdullah Abdulmohsin; AlHerbish, Abdullah Sulaiman

2016-01-01

Previous growth charts for Saudi children have not included detailed tables and parameters needed for research and incorporation in electronic records. The objective of this report is to publish the L, M, and S parameters and percentiles as well as the corresponding growth charts for Saudi preschool children. Community-based survey and measurement of growth parameters in a sample selected by a multistage probability procedure. A stratified listing of the Saudi population. Raw data from the previous nationally-representative sample were reanalyzed using the Lambda-Mu-Sigma (LMS) methodology to calculate the L, M, and S parameters of percentiles (from 3rd to 97th) for weight, length/height, head circumference, and body mass index-for-age, and weight for-length/height for boys and girls from birth to 60 months. Length or height and weight of Saudi preschool children. There were 15601 Saudi children younger than 60 months of age, 7896 (50.6 %) were boys. The LMS parameters for weight for age from birth to 60 months (5 years) are reported for the 3rd, 5th, 10th, 25th, 50th, 75th, 90th, 95th, and 97th percentiles as well as the corresponding graphs. Similarly, the LMS parameters for length/height-for-age, head circumference-for-age, weight-for-length/height and body mass index-for-age (BMi) are shown with the corresponding graphs for boys and girls. Using the data in this report, clinicians and researchers can assess the growth of Saudi preschool children. The report does not reflect interregional variations in growth.

Association of early- and adult-life socioeconomic circumstances with muscle strength in older age.

PubMed

Cheval, Boris; Boisgontier, Matthieu P; Orsholits, Dan; Sieber, Stefan; Guessous, Idris; Gabriel, Rainer; Stringhini, Silvia; Blane, David; van der Linden, Bernadette W A; Kliegel, Matthias; Burton-Jeangros, Claudine; Courvoisier, Delphine S; Cullati, Stéphane

2018-05-01

socioeconomic circumstances (SEC) during a person's lifespan influence a wide range of health outcomes. However, solid evidence of the association of early- and adult-life SEC with health trajectories in ageing is still lacking. This study assessed whether early-life SEC are associated with muscle strength in later life-a biomarker of health-and whether this relationship is caused by adult-life SEC and health behaviours. we used data from the Survey of Health Ageing and Retirement in Europe, a 12-year population-based cohort study with repeated measurement in six waves (2004-15) and retrospective collection of life-course data. Participants' grip strength was assessed by using a handheld dynamometer. Confounder-adjusted logistic mixed-effect models were used to examine the associations of early- and adult-life SEC with the risk of low muscle strength (LMS) in older age. a total of 24,179 participants (96,375 observations) aged 50-96 living in 14 European countries were included in the analyses. Risk of LMS was increased with disadvantaged relative to advantaged early-life SEC. The association between risk of LMS and disadvantaged early-life SEC gradually decreased when adjusting for adult-life SEC for both sexes and with unhealthy behaviours for women. After adjusting for these factors, all associations between risk of LMS and early-life SEC remained significant for women. early-life SEC are associated with muscle strength after adjusting for adult-life SEC and behavioural lifestyle factors, especially in women, which suggests that early life may represent a sensitive period for future health.

Accurate motion parameter estimation for colonoscopy tracking using a regression method

NASA Astrophysics Data System (ADS)

Liu, Jianfei; Subramanian, Kalpathi R.; Yoo, Terry S.

2010-03-01

Co-located optical and virtual colonoscopy images have the potential to provide important clinical information during routine colonoscopy procedures. In our earlier work, we presented an optical flow based algorithm to compute egomotion from live colonoscopy video, permitting navigation and visualization of the corresponding patient anatomy. In the original algorithm, motion parameters were estimated using the traditional Least Sum of squares(LS) procedure which can be unstable in the context of optical flow vectors with large errors. In the improved algorithm, we use the Least Median of Squares (LMS) method, a robust regression method for motion parameter estimation. Using the LMS method, we iteratively analyze and converge toward the main distribution of the flow vectors, while disregarding outliers. We show through three experiments the improvement in tracking results obtained using the LMS method, in comparison to the LS estimator. The first experiment demonstrates better spatial accuracy in positioning the virtual camera in the sigmoid colon. The second and third experiments demonstrate the robustness of this estimator, resulting in longer tracked sequences: from 300 to 1310 in the ascending colon, and 410 to 1316 in the transverse colon.

Low complexity adaptive equalizers for underwater acoustic communications

NASA Astrophysics Data System (ADS)

Soflaei, Masoumeh; Azmi, Paeiz

2014-08-01

Interference signals due to scattering from surface and reflecting from bottom is one of the most important problems of reliable communications in shallow water channels. To solve this problem, one of the best suggested ways is to use adaptive equalizers. Convergence rate and misadjustment error in adaptive algorithms play important roles in adaptive equalizer performance. In this paper, affine projection algorithm (APA), selective regressor APA(SR-APA), family of selective partial update (SPU) algorithms, family of set-membership (SM) algorithms and selective partial update selective regressor APA (SPU-SR-APA) are compared with conventional algorithms such as the least mean square (LMS) in underwater acoustic communications. We apply experimental data from the Strait of Hormuz for demonstrating the efficiency of the proposed methods over shallow water channel. We observe that the values of the steady-state mean square error (MSE) of SR-APA, SPU-APA, SPU-normalized least mean square (SPU-NLMS), SPU-SR-APA, SM-APA and SM-NLMS algorithms decrease in comparison with the LMS algorithm. Also these algorithms have better convergence rates than LMS type algorithm.

Estimating Latent Variable Interactions With Non-Normal Observed Data: A Comparison of Four Approaches

PubMed Central

Cham, Heining; West, Stephen G.; Ma, Yue; Aiken, Leona S.

2012-01-01

A Monte Carlo simulation was conducted to investigate the robustness of four latent variable interaction modeling approaches (Constrained Product Indicator [CPI], Generalized Appended Product Indicator [GAPI], Unconstrained Product Indicator [UPI], and Latent Moderated Structural Equations [LMS]) under high degrees of non-normality of the observed exogenous variables. Results showed that the CPI and LMS approaches yielded biased estimates of the interaction effect when the exogenous variables were highly non-normal. When the violation of non-normality was not severe (normal; symmetric with excess kurtosis < 1), the LMS approach yielded the most efficient estimates of the latent interaction effect with the highest statistical power. In highly non-normal conditions, the GAPI and UPI approaches with ML estimation yielded unbiased latent interaction effect estimates, with acceptable actual Type-I error rates for both the Wald and likelihood ratio tests of interaction effect at N ≥ 500. An empirical example illustrated the use of the four approaches in testing a latent variable interaction between academic self-efficacy and positive family role models in the prediction of academic performance. PMID:23457417

Recursive least-squares learning algorithms for neural networks

NASA Astrophysics Data System (ADS)

Lewis, Paul S.; Hwang, Jenq N.

1990-11-01

This paper presents the development of a pair of recursive least squares (ItLS) algorithms for online training of multilayer perceptrons which are a class of feedforward artificial neural networks. These algorithms incorporate second order information about the training error surface in order to achieve faster learning rates than are possible using first order gradient descent algorithms such as the generalized delta rule. A least squares formulation is derived from a linearization of the training error function. Individual training pattern errors are linearized about the network parameters that were in effect when the pattern was presented. This permits the recursive solution of the least squares approximation either via conventional RLS recursions or by recursive QR decomposition-based techniques. The computational complexity of the update is 0(N2) where N is the number of network parameters. This is due to the estimation of the N x N inverse Hessian matrix. Less computationally intensive approximations of the ilLS algorithms can be easily derived by using only block diagonal elements of this matrix thereby partitioning the learning into independent sets. A simulation example is presented in which a neural network is trained to approximate a two dimensional Gaussian bump. In this example RLS training required an order of magnitude fewer iterations on average (527) than did training with the generalized delta rule (6 1 BACKGROUND Artificial neural networks (ANNs) offer an interesting and potentially useful paradigm for signal processing and pattern recognition. The majority of ANN applications employ the feed-forward multilayer perceptron (MLP) network architecture in which network parameters are " trained" by a supervised learning algorithm employing the generalized delta rule (GDIt) [1 2]. The GDR algorithm approximates a fixed step steepest descent algorithm using derivatives computed by error backpropagatiori. The GDII algorithm is sometimes referred to as the backpropagation algorithm. However in this paper we will use the term backpropagation to refer only to the process of computing error derivatives. While multilayer perceptrons provide a very powerful nonlinear modeling capability GDR training can be very slow and inefficient. In linear adaptive filtering the analog of the GDR algorithm is the leastmean- squares (LMS) algorithm. Steepest descent-based algorithms such as GDR or LMS are first order because they use only first derivative or gradient information about the training error to be minimized. To speed up the training process second order algorithms may be employed that take advantage of second derivative or Hessian matrix information. Second order information can be incorporated into MLP training in different ways. In many applications especially in the area of pattern recognition the training set is finite. In these cases block learning can be applied using standard nonlinear optimization techniques [3 4 5].

A new optimized GA-RBF neural network algorithm.

PubMed

Jia, Weikuan; Zhao, Dean; Shen, Tian; Su, Chunyang; Hu, Chanli; Zhao, Yuyan

2014-01-01

When confronting the complex problems, radial basis function (RBF) neural network has the advantages of adaptive and self-learning ability, but it is difficult to determine the number of hidden layer neurons, and the weights learning ability from hidden layer to the output layer is low; these deficiencies easily lead to decreasing learning ability and recognition precision. Aiming at this problem, we propose a new optimized RBF neural network algorithm based on genetic algorithm (GA-RBF algorithm), which uses genetic algorithm to optimize the weights and structure of RBF neural network; it chooses new ways of hybrid encoding and optimizing simultaneously. Using the binary encoding encodes the number of the hidden layer's neurons and using real encoding encodes the connection weights. Hidden layer neurons number and connection weights are optimized simultaneously in the new algorithm. However, the connection weights optimization is not complete; we need to use least mean square (LMS) algorithm for further leaning, and finally get a new algorithm model. Using two UCI standard data sets to test the new algorithm, the results show that the new algorithm improves the operating efficiency in dealing with complex problems and also improves the recognition precision, which proves that the new algorithm is valid.

Species-related difference between limonin and obacunone among five liver microsomes and zebrafish using ultra-high-performance liquid chromatography coupled with a LTQ-Orbitrap mass spectrometer.

PubMed

Ren, Wei; Li, Yan; Zuo, Ran; Wang, Hong-Jie; Si, Nan; Zhao, Hai-Yu; Han, Ling-Yu; Yang, Jian; Bian, Bao-Lin

2014-11-15

Limonin and obacunone are two major limonoids distributed in the Rutaceae and Meliaceae families. Their defined anti-tumor activity is closely connected with the furan ring and the multi-carbonyls in their structures. In vivo and in vitro biotransformations may influence their structures and further change their effects. The metabolic profiles of limonin and obacunone have not been studied previously. In order to clarify their in vivo and in vitro metabolism, a comparative investigation of their metabolic pathways in five different species of liver microsomes and zebrafish was carried out. In the present study, ultra-high-performance liquid chromatography coupled with high-resolution mass spectrometry (UHPLC/HRMS) and related electrospray ionization (ESI) tandem mass spectrometric (MS/MS) dissociation of limonin and obacunone were applied for the analysis. Each metabolite was identified by its accurate mass data. Human liver microsomes (HLMs), monkey liver microsomes (MLMs), dog liver microsomes (DLMs), rat liver microsomes (RLMs), mice liver microsomes (XLMs) and zebrafish were included in the biotransformations. One phase I metabolite of limonin (M1-1) and two phase I metabolites of obacunone (M2-1, M2-2) were identified by accurate mass measurement and MS/MS fragmentation behaviors. A reduction reaction was regarded as the major metabolic pathway of limonoids in liver microsomes. The reduction reaction site of M1-1 and M2-1 was at the C-16 carbonyl, while for M2-2 it was at C-7. M1-1 was the major and unique metabolite of limonin and the metabolic rate of limonin varied from 11.5% to 17.8% in liver microsomes (LMs). M2-2 was the main metabolite of obacunone in LMs and zebrafish. M1-1 and M2-1 were only detected in LMs while M2-2 was found in both LMs and zebrafish incubation systems. The metabolic rate of obacunone varied from 2.5% to 19.1% and the content of M2-2 was about five times higher than that of M2-1. The ESI-HR-MS/MS fragmentation behaviors of limonin and obacunone were investigated for the first time. A qualitative and semi-quantitative method was developed for the in vivo and in vitro metabolic analysis of limonin and obacunone. The results demonstrated that the metabolic processes of limonin and obacunone were different between LMs and zebrafish. However, both of these two parent compounds presented similar metabolic processes in five species of LMs. This was caused by the metabolic difference between mammals and fish or because limonin probably cannot be absorbed in zebrafish. Copyright © 2014 John Wiley & Sons, Ltd.

Designing and assessing fixed dental prostheses 2 multimedia-based education in dentistry students.

PubMed

Jahandideh, Yousef; Roohi Balasi, Leila; Vadiati Saberi, Bardia; Dadgaran, Ideh

2016-01-01

Background: Above all methods effective learning results from decent training, acquired in the proper environment and encouraging creative methods. Computer-assisted training by educational software is considered a fundamental measure to improve medical and dentistry education systems. This study aims to design and assess fixed dental prostheses via 2 multimedia instructional contents at the Guilan dentistry school. Methods: This is a descriptive and cross-sectional study. First off, the instructional content was analyzed. The software used to produce multimedia was the iSpring suite Ver.7.0. After designing the instructional multimedia, this software was loaded by LMS. Sixty-nine dentistry students in the 5th semester at Guilan Dentistry School were selected via convenience sampling. At the end of the course, a structured questionnaire containing 26 items were handed to the students to evaluate the instructional multimedia quality. Results: Mean ±SD age was 24.68±3.24 years, 43 were women (62.4%) and 26 were men (37.6%) -the majority of 76.8% used the internet at home. A portion of 33.3% were inclined to use multimedia and the internet with in-person training. About 60% declared that multimedia quality as being good. Conclusion: the instructional multimedia designs which are compatible with lesson objectives and audiovisual facilities can have a great effect on the student's satisfaction. Preparing instructional multimedia makes the instructional content easily accessible for students to be able to review it several times at the proper opportunity and if presented through LMS they would be able to study the lesson subject wherever and whenever accessing the internet.

Improved neural network based scene-adaptive nonuniformity correction method for infrared focal plane arrays.

PubMed

Lai, Rui; Yang, Yin-tang; Zhou, Duan; Li, Yue-jin

2008-08-20

An improved scene-adaptive nonuniformity correction (NUC) algorithm for infrared focal plane arrays (IRFPAs) is proposed. This method simultaneously estimates the infrared detectors' parameters and eliminates the nonuniformity causing fixed pattern noise (FPN) by using a neural network (NN) approach. In the learning process of neuron parameter estimation, the traditional LMS algorithm is substituted with the newly presented variable step size (VSS) normalized least-mean square (NLMS) based adaptive filtering algorithm, which yields faster convergence, smaller misadjustment, and lower computational cost. In addition, a new NN structure is designed to estimate the desired target value, which promotes the calibration precision considerably. The proposed NUC method reaches high correction performance, which is validated by the experimental results quantitatively tested with a simulative testing sequence and a real infrared image sequence.

A splice donor mutation in NAA10 results in the dysregulation of the retinoic acid signaling pathway and causes Lenz microphthalmia syndrome

PubMed Central

Esmailpour, Taraneh; Riazifar, Hamidreza; Liu, Linan; Donkervoort, Sandra; Huang, Vincent H; Madaan, Shreshtha; Shoucri, Bassem M; Busch, Anke; Wu, Jie; Towbin, Alexander; Chadwick, Robert B; Sequeira, Adolfo; Vawter, Marquis P; Sun, Guoli; Johnston, Jennifer J; Biesecker, Leslie G; Kawaguchi, Riki; Sun, Hui; Kimonis, Virginia; Huang, Taosheng

2014-01-01

Introduction Lenz microphthalmia syndrome (LMS) is a genetically heterogeneous X-linked disorder characterised by microphthalmia/anophthalmia, skeletal abnormalities, genitourinary malformations, and anomalies of the digits, ears, and teeth. Intellectual disability and seizure disorders are seen in about 60% of affected males. To date, no gene has been identified for LMS in the microphthalmia syndrome 1 locus (MCOPS1). In this study, we aim to find the disease-causing gene for this condition. Methods and results Using exome sequencing in a family with three affected brothers, we identified a mutation in the intron 7 splice donor site (c.471+2T→A) of the N-acetyltransferase NAA10 gene. NAA10 has been previously shown to be mutated in patients with Ogden syndrome, which is clinically distinct from LMS. Linkage studies for this family mapped the disease locus to Xq27-Xq28, which was consistent with the locus of NAA10. The mutation co-segregated with the phenotype and cDNA analysis showed aberrant transcripts. Patient fibroblasts lacked expression of full length NAA10 protein and displayed cell proliferation defects. Expression array studies showed significant dysregulation of genes associated with genetic forms of anophthalmia such as BMP4, STRA6, and downstream targets of BCOR and the canonical WNT pathway. In particular, STRA6 is a retinol binding protein receptor that mediates cellular uptake of retinol/vitamin A and plays a major role in regulating the retinoic acid signalling pathway. A retinol uptake assay showed that retinol uptake was decreased in patient cells. Conclusions We conclude that the NAA10 mutation is the cause of LMS in this family, likely through the dysregulation of the retinoic acid signalling pathway. PMID:24431331

Photochemical internalization (PCI) of bleomycin is equally effective in two dissimilar leiomyosarcoma xenografts in athymic mice.

PubMed

Sellevold, Simen; Peng, Qian; Fremstedal, Ane Sofie Viset; Berg, Kristian

2017-12-01

Photochemical internalization (PCI) is a novel technique for delivery of active macromolecules into cancerous cells, via light activation of a specific photosensitizer and a low dose systemic drug. Numerous pre-clinical studies and one clinical trial have confirmed the treatment potential in carcinomas. Soft tissue sarcomas are rare and generally resistant to radio- and chemotherapy. Due to treatment resistance and surgical morbidity in sarcoma care, we seek to increase knowledge on PCI effects in sarcomas by studying two different, but closely related leiomyosarcomas. MES-SA and SK-LMS-1 tumours were established in the leg muscles of athymic mice. Treatment effects after AlPcS 2a -PCI of bleomycin, PCI with no drug (photodynamic therapy, PDT) and control groups were evaluated by: 1) assessment of tumour growth, 2) uptake of contrast agent during MRI and 3) histopathology. PCI of bleomycin induced a similar and significant increase in time to reach the end point in both tumour models, while neither responded to AlPcS 2a -PDT. In the MES-SA tumours PCI reduced the growth rate, while in the SK-LMS-1 tumours the growth was blocked for 12days followed by exponential growth close to that of untreated tumours. SK-LMS-1 tumours were more homogenously and better vascularized than MES-SA. After PCI the vascular shutdown was more complete in the SK-LMS-1 tumours than in the MES-SA tumours. AlPcS2a-based PCI, but not PDT, induced significant tumour growth delay in the evaluated sarcomas. Cellular responsiveness to bleomycin and tumour vascularity are identified as predictive markers for PCI treatment effects. Copyright © 2017 Elsevier B.V. All rights reserved.

LMS tables for waist circumference and waist–height ratio in Colombian adults: analysis of nationwide data 2010

PubMed Central

Ramírez-Vélez, R; Correa-Bautista, J E; Martínez-Torres, J; Méneses-Echavez, J F; González-Ruiz, K; González-Jiménez, E; Schmidt-RioValle, J; Lobelo, F

2016-01-01

Background/Objectives: Indices predictive of central obesity include waist circumference (WC) and waist-to-height ratio (WHtR). These data are lacking for Colombian adults. This study aims at establishing smoothed centile charts and LMS tables for WC and WHtR; appropriate cutoffs were selected using receiver-operating characteristic analysis based on data from the representative sample. Subjects/Methods: We used data from the cross-sectional, national representative nutrition survey (ENSIN, 2010). A total of 83 220 participants (aged 20–64) were enroled. Weight, height, body mass index (BMI), WC and WHtR were measured and percentiles calculated using the LMS method (L (curve Box-Cox), M (curve median), and S (curve coefficient of variation)). Receiver operating characteristics curve analyses were used to evaluate the optimal cutoff point of WC and WHtR for overweight and obesity based on WHO definitions. Results: Reference values for WC and WHtR are presented. Mean WC and WHtR increased with age for both genders. We found a strong positive correlation between WC and BMI (r=0.847, P< 0.01) and WHtR and BMI (r=0.878, P<0.01). In obese men, the cutoff point value is 96.6 cm for the WC. In women, the cutoff point value is 91.0 cm for the WC. Receiver operating characteristic curve for WHtR was also obtained and the cutoff point value of 0.579 in men, and in women the cutoff point value was 0.587. A high sensitivity and specificity were obtained. Conclusions: This study presents first reference values of WC and WHtR for Colombians aged 20–64. Through LMS tables for adults, we hope to provide quantitative tools to study obesity and its complications. PMID:27026425

Reference Values for Spirometry Derived Using Lambda, Mu, Sigma (LMS) Method in Korean Adults: in Comparison with Previous References.

PubMed

Jo, Bum Seak; Myong, Jun Pyo; Rhee, Chin Kook; Yoon, Hyoung Kyu; Koo, Jung Wan; Kim, Hyoung Ryoul

2018-01-15

The present study aimed to update the prediction equations for spirometry and their lower limits of normal (LLN) by using the lambda, mu, sigma (LMS) method and to compare the outcomes with the values of previous spirometric reference equations. Spirometric data of 10,249 healthy non-smokers (8,776 females) were extracted from the fourth and fifth versions of the Korea National Health and Nutrition Examination Survey (KNHANES IV, 2007-2009; V, 2010-2012). Reference equations were derived using the LMS method which allows modeling skewness (lambda [L]), mean (mu [M]), and coefficient of variation (sigma [S]). The outcome equations were compared with previous reference values. Prediction equations were presented in the following form: predicted value = e{a + b × ln(height) + c × ln(age) + M - spline}. The new predicted values for spirometry and their LLN derived using the LMS method were shown to more accurately reflect transitions in pulmonary function in young adults than previous prediction equations derived using conventional regression analysis in 2013. There were partial discrepancies between the new reference values and the reference values from the Global Lung Function Initiative in 2012. The results should be interpreted with caution for young adults and elderly males, particularly in terms of the LLN for forced expiratory volume in one second/forced vital capacity in elderly males. Serial spirometry follow-up, together with correlations with other clinical findings, should be emphasized in evaluating the pulmonary function of individuals. Future studies are needed to improve the accuracy of reference data and to develop continuous reference values for spirometry across all ages. © 2018 The Korean Academy of Medical Sciences.

The prevalence of the ponticulus posticus (arcuate foramen) and its importance in the Goel-Harms procedure: meta-analysis and review of the literature.

PubMed

Elliott, Robert E; Tanweer, Omar

2014-01-01

We reviewed published radiographic and cadaver series describing the incidence of the anatomical anomaly ponticulus posticus and discuss its relevance to C1 lateral mass screw (C1LMS) insertion. Online databases were searched for English-language articles describing the presence of ponticulus posticus in cadaver and radiographic studies. Forty-four reports describing 21,789 patients (n = 15,542) or bony/cadaver specimens (n = 6247) fulfilled inclusion criteria. Meta-analysis techniques were applied to estimate the prevalence of this anomaly. The overall prevalence of ponticulus posticus was 16.7%. The anomaly was identified in 18.8% of cadaver, 17.2% of computed tomographic, and 16.6% on radiographic studies. The anomaly composed a complete foramen in 9.3% of patients and was partial/incomplete in 8.7%. It was present bilaterally in 5.4% of cases and unilateral in 7.6%. There was no significant difference in prevalence between males (15.8%) and females (14.6%). Review of that literature demonstrated a dramatic increase in the number of patients treated with C1LMS through the posterior arch since first described in 2002, necessitating recognition of this anomaly when performing the Goel-Harms procedure. The atlantal anomaly ponticulus posticus is not rare, occurring in 16.7% of patients in radiographic and cadaver studies. This anomaly may give the false impression that the posterior arch of the atlas is of adequate size to accommodate a C1LMS and may lead to inadvertent vertebral artery injury. Careful assessment via preoperative multiplanar computed tomographic imaging should be performed before consideration of C1LMS implantation. Copyright © 2014 Elsevier Inc. All rights reserved.

The Least Mean Squares Adaptive FIR Filter for Narrow-Band RFI Suppression in Radio Detection of Cosmic Rays

NASA Astrophysics Data System (ADS)

Szadkowski, Zbigniew; Głas, Dariusz

2017-06-01

Radio emission from the extensive air showers (EASs), initiated by ultrahigh-energy cosmic rays, was theoretically suggested over 50 years ago. However, due to technical limitations, successful collection of sufficient statistics can take several years. Nowadays, this detection technique is used in many experiments consisting in studying EAS. One of them is the Auger Engineering Radio Array (AERA), located within the Pierre Auger Observatory. AERA focuses on the radio emission, generated by the electromagnetic part of the shower, mainly in geomagnetic and charge excess processes. The frequency band observed by AERA radio stations is 30-80 MHz. Thus, the frequency range is contaminated by human-made and narrow-band radio frequency interferences (RFIs). Suppression of contaminations is very important to lower the rate of spurious triggers. There are two kinds of digital filters used in AERA radio stations to suppress these contaminations: the fast Fourier transform median filter and four narrow-band IIR-notch filters. Both filters have worked successfully in the field for many years. An adaptive filter based on a least mean squares (LMS) algorithm is a relatively simple finite impulse response (FIR) filter, which can be an alternative for currently used filters. Simulations in MATLAB are very promising and show that the LMS filter can be very efficient in suppressing RFI and only slightly distorts radio signals. The LMS algorithm was implemented into a Cyclone V field programmable gate array for testing the stability, RFI suppression efficiency, and adaptation time to new conditions. First results show that the FIR filter based on the LMS algorithm can be successfully implemented and used in real AERA radio stations.

Henricks examines the computer systems under the Spacelab floor

NASA Image and Video Library

1996-07-09

STS078-432-009 (20 June-7 July 1996) --- Among the inflight maintenance (IFM) chores that were handled by the crew members during their almost 17 days in space aboard the space shuttle Columbia was one that involved going into the bay beneath the floor of the Life and Microgravity Spacelab (LMS-1) Science Module. Astronaut Terence T. (Tom) Henricks, mission commander, shines a tiny flashlight onto some cables related to LMS-1 supported computer systems. As in the case of the other IFM chores, Henricks' efforts were successful. He was joined by four other NASA astronauts and two international payload specialists for the space shuttle duration record-setting mission.

An Adaptive Pheromone Updation of the Ant-System using LMS Technique

NASA Astrophysics Data System (ADS)

Paul, Abhishek; Mukhopadhyay, Sumitra

2010-10-01

We propose a modified model of pheromone updation for Ant-System, entitled as Adaptive Ant System (AAS), using the properties of basic Adaptive Filters. Here, we have exploited the properties of Least Mean Square (LMS) algorithm for the pheromone updation to find out the best minimum tour for the Travelling Salesman Problem (TSP). TSP library has been used for the selection of benchmark problem and the proposed AAS determines the minimum tour length for the problems containing large number of cities. Our algorithm shows effective results and gives least tour length in most of the cases as compared to other existing approaches.

High resolution laser micro sintering / melting using q-switched and high brilliant laser radiation

NASA Astrophysics Data System (ADS)

Exner, H.; Streek, A.

2015-03-01

Since the discovery of selective laser sintering/melting, numerous modifications have been made to upgrade or customize this technology for industrial purposes. Laser micro sintering (LMS) is one of those modifications: Powders with particles in the range of a few micrometers are used to obtain products with highly resolved structures. Pulses of a q-switched laser had been considered necessary in order to generate sinter layers from the micrometer scaled metal powders. LMS has been applied with powders from metals as well as from ceramic and cermet feedstock's to generate micro parts. Recent technological progress and the application of high brilliant continuous laser radiation have now allowed an efficient laser sintering/melting of micrometer scaled metal powders. Thereby it is remarkable that thin sinter layers are generated using high continuous laser power. The principles of the process, the state of the art in LMS concerning its advantages and limitations and furthermore the latest results of the recent development of this technology will be presented. Laser Micro Sintering / Laser Micro Melting (LMM) offer a vision for a new dimension of additive fabrication of miniature and precise parts also with application potential in all engineering fields.

An LMS Programming Scheme and Floating-Gate Technology Enabled Trimmer-Less and Low Voltage Flame Detection Sensor.

PubMed

Iglesias-Rojas, Juan Carlos; Gomez-Castañeda, Felipe; Moreno-Cadenas, Jose Antonio

2017-06-14

In this paper, a Least Mean Square (LMS) programming scheme is used to set the offset voltage of two operational amplifiers that were built using floating-gate transistors, enabling a 0.95 V RMS trimmer-less flame detection sensor. The programming scheme is capable of setting the offset voltage over a wide range of values by means of electron injection. The flame detection sensor consists of two programmable offset operational amplifiers; the first amplifier serves as a 26 μV offset voltage follower, whereas the second amplifier acts as a programmable trimmer-less voltage comparator. Both amplifiers form the proposed sensor, whose principle of functionality is based on the detection of the electrical changes produced by the flame ionization. The experimental results show that it is possible to measure the presence of a flame accurately after programming the amplifiers with a maximum of 35 LMS-algorithm iterations. Current commercial flame detectors are mainly used in absorption refrigerators and large industrial gas heaters, where a high voltage AC source and several mechanical trimmings are used in order to accurately measure the presence of the flame.

Probing the Allende meteorite with a miniature laser-ablation mass analyser for space application

NASA Astrophysics Data System (ADS)

Neuland, M. B.; Meyer, S.; Mezger, K.; Riedo, A.; Tulej, M.; Wurz, P.

2014-10-01

We measured the elemental composition on a sample of Allende meteorite with a miniature laser ablation mass spectrometer. This laser mass spectrometer (LMS) has been designed and built at the University of Bern in the Department of Space Research and Planetary Sciences with the objective of using such an instrument on a space mission. Utilising the meteorite Allende as the test sample in this study, it is demonstrated that the instrument allows the in situ determination of the elemental composition and thus mineralogy and petrology of untreated rocky samples, particularly on planetary surfaces. In total, 138 measurements of elemental compositions have been carried out on an Allende sample. The mass spectrometric data are evaluated and correlated with an optical image. It is demonstrated that by illustrating the measured elements in the form of mineralogical maps, LMS can serve as an element imaging instrument with a very high spatial resolution of μm scale. The detailed analysis also includes a mineralogical evaluation and an investigation of the volatile element content of Allende. All findings are in good agreement with published data and underline the high sensitivity, accuracy and capability of LMS as a mass analyser for space exploration.

Protein Crystal Movements and Fluid Flows During Microgravity Growth

NASA Technical Reports Server (NTRS)

Boggon, Titus J.; Chayen, Naomi E.; Snell, Edward H.; Dong, Jun; Lautenschlager, Peter; Potthast, Lothar; Siddons, D. Peter; Stojanoff, Vivian; Gordon, Elspeth; Thompson, Andrew W.;

An LMS Programming Scheme and Floating-Gate Technology Enabled Trimmer-Less and Low Voltage Flame Detection Sensor

PubMed Central

Iglesias-Rojas, Juan Carlos; Gomez-Castañeda, Felipe; Moreno-Cadenas, Jose Antonio

2017-01-01

In this paper, a Least Mean Square (LMS) programming scheme is used to set the offset voltage of two operational amplifiers that were built using floating-gate transistors, enabling a 0.95 VRMS trimmer-less flame detection sensor. The programming scheme is capable of setting the offset voltage over a wide range of values by means of electron injection. The flame detection sensor consists of two programmable offset operational amplifiers; the first amplifier serves as a 26 μV offset voltage follower, whereas the second amplifier acts as a programmable trimmer-less voltage comparator. Both amplifiers form the proposed sensor, whose principle of functionality is based on the detection of the electrical changes produced by the flame ionization. The experimental results show that it is possible to measure the presence of a flame accurately after programming the amplifiers with a maximum of 35 LMS-algorithm iterations. Current commercial flame detectors are mainly used in absorption refrigerators and large industrial gas heaters, where a high voltage AC source and several mechanical trimmings are used in order to accurately measure the presence of the flame. PMID:28613250

Data Validation Package October 2016 Groundwater and Surface Water Sampling at the Monticello, Utah, Disposal and Processing Sites January 2017

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nguyen, Jason; Smith, Fred

Sampling Period: October 10–12, 2016. This semiannual event includes sampling groundwater and surface water at the Monticello Disposal and Processing Sites. Sampling and analyses were conducted as specified in the Sampling and Analysis Plan for U.S. Department of Energy Office of Legacy Management Sites (LMS/PRO/S04351, continually updated) and Program Directive MNT-2016-01. Samples were collected from 54 of 64 planned locations (16 of 17 former mill site wells, 15 of 18 downgradient wells, 7 of 9 downgradient permeable reactive barrier wells, 3 of 3 bedrock wells, 4 of 7 seeps and wetlands, and 9 of 10 surface water locations).

Entrepreneurial model based technology creative industries sector software through the use of free open source software for Universitas Pendidikan Indonesia students

NASA Astrophysics Data System (ADS)

Hasan, B.; Hasbullah; Purnama, W.; Hery, A.

2016-04-01

Creative industry development areas of software by using Free Open Source Software (FOSS) is expected to be one of the solutions to foster new entrepreneurs of the students who can open job opportunities and contribute to economic development in Indonesia. This study aims to create entrepreneurial coaching model based on the creative industries by utilizing FOSS software field as well as provide understanding and fostering entrepreneurial creative industries based field software for students of Universitas Pendidikan Indonesia. This activity phase begins with identifying entrepreneurs or business software technology that will be developed, training and mentoring, apprenticeship process at industrial partners, creation of business plans and monitoring and evaluation. This activity involves 30 UPI student which has the motivation to self-employment and have competence in the field of information technology. The results and outcomes expected from these activities is the birth of a number of new entrepreneurs from the students engaged in the software industry both software in the world of commerce (e-commerce) and education/learning (e-learning/LMS) and games.

Tribological properties of CVD diamond coated ceramic surfaces

NASA Astrophysics Data System (ADS)

Abreu, Cristiano Simoes de

Recent developments in chemical vapour deposited (CVD) diamond coatings have attracted considerable interest and a host of new applications, each more challenging than the others. This increased attention results from the fact that CVD diamond lms retain to a large extent the outstanding physical and chemical properties of natural single crystal diamond such as extreme hardness, chemical inertness and high corrosion resistance, optical transparency and high thermal conductivity. Diamond features also surprisingly low friction and high wear resistance in unlubricated sliding contacts. Moreover, as opposed to natural diamond where the friction and wear behaviour is highly dependent on crystal orientation, polycrystalline CVD diamond lms supersede the monocrystalline variety due to isotropic tribological properties and possibility of coating complex shapes. Several materials have been tested and more or less successfully used as substrates for CVD diamond coatings. Nonetheless, satisfactory adherence of diamond coatings lms is often only attainable by the use of interlayers, in order to compensate for the large interfacial thermal expansion mismatch between the coating and substrate, which represent an additional processing step and added costs. A promising route will consist in using substrate materials with a low thermal expansion mismatch relative to that of diamond and, therefore, enhanced 1m adhesion. Among these, the ceramic silicon nitride (Si3N4) arises as a serious candidate. As a general rule, available literature regarding the tribological performance of CVD diamond coated Si3N4 lms is scarce, and the few available tribological data only deals with low applied loads. That being said, the correct tribological assessment of CVD diamond coated Si3N4 lms under more realistic sliding conditions, reproducing the stresses found in applications fields such as the fluid handling and metalworking industry, as well as in emerging biotribological areas, is on the agenda. In the present work, homologous tribological tests involving two distinct crystalline scale diamond coatings, namely microcrystalline diamond (MCD) and nanocrystalline diamond (NCD) coatings, were performed under unlubricated and water lubricated sliding conditions. The friction and wear behaviour of each diamond system was assessed using a reciprocating motion type geometry under moderated to high applied normal loads, reaching maximum values as high as 160 N in the case of lubricated MCD lms. Influence of grain size effects and surface pre-treatments of the substrate on the tribological performance of MCD and NCD coatings, respectively, has also been undertaken. Several complementary characterisation techniques, including scanning electron microscopy, atomic force microscopy and micro-Raman studies, were used in order to assess the diamond quality, stress state, topography evolution of worn surfaces, wear resistance and prevailing wear mechanisms. The distinct friction regimes occurring for diamond-on-diamond dry sliding tests and condition for the delamination of the coating were also studied by the means of acoustic emission measurements. The friction performance of the MCD coatings under dry sliding were characterised by very low steady-state friction coeficient values in the range 0:03 - 0:04, regardless of the applied load. Such exceptional atrituous behaviour under unlubricated conditions was accompanied by a high resistance to wear damage, with wear rates characteristic of mild to very mild wear regimes (10. -8-10. -7mm3N-1m-1). The MCD water lubricated systems revealed even lower friction resistance (0.01 - 0.03), as well as a two-fold increase on the threshold load (150 N) prior to lm delamination under tribological stress. The inherent lower surface roughness of the NCD lms was responsible for a marginally lower steady-state friction response (0.02 - 0.03) in relation to the MCD coatings, and showed to be independent of the nishing condition and substrate surface pre-treatments. Moreover, the moderate initial friction response occurring during the running-in period of accommodation between opposing MCD surfaces was greatly suppressed by the much lower starting surface roughness found in the NCD coatings. Similarly to what was observed in water lubricated MCD coatings, homologous pairs of NCD lms sliding in distilled water displayed an improved tribological performance characterised by a high resistance to wear damage (10. -8 mm. 3N-1m-1) and higher threshold loads under tribologicalaction, making them promising candidates for highly demanding tribological applications, namely in biotribology where their clinical use e.g. in total arthroplasty is a possibility.

Designing and assessing fixed dental prostheses 2 multimedia-based education in dentistry students

PubMed Central

Jahandideh, Yousef; Roohi Balasi, Leila; Vadiati Saberi, Bardia; Dadgaran, Ideh

2016-01-01

Background: Above all methods effective learning results from decent training, acquired in the proper environment and encouraging creative methods. Computer-assisted training by educational software is considered a fundamental measure to improve medical and dentistry education systems. This study aims to design and assess fixed dental prostheses via 2 multimedia instructional contents at the Guilan dentistry school. Methods: This is a descriptive and cross-sectional study. First off, the instructional content was analyzed. The software used to produce multimedia was the iSpring suite Ver.7.0. After designing the instructional multimedia, this software was loaded by LMS. Sixty-nine dentistry students in the 5th semester at Guilan Dentistry School were selected via convenience sampling. At the end of the course, a structured questionnaire containing 26 items were handed to the students to evaluate the instructional multimedia quality. Results: Mean ±SD age was 24.68±3.24 years, 43 were women (62.4%) and 26 were men (37.6%) –the majority of 76.8% used the internet at home. A portion of 33.3% were inclined to use multimedia and the internet with in-person training. About 60% declared that multimedia quality as being good. Conclusion: the instructional multimedia designs which are compatible with lesson objectives and audiovisual facilities can have a great effect on the student's satisfaction. Preparing instructional multimedia makes the instructional content easily accessible for students to be able to review it several times at the proper opportunity and if presented through LMS they would be able to study the lesson subject wherever and whenever accessing the internet. PMID:28491830

Unique Results and Lessons Learned from the TSS Missions

NASA Technical Reports Server (NTRS)

Stone, Nobie H.

2016-01-01

In 1924, Irvin Langmuir and H. M. Mott-Smith published a theoretical model for the complex plasma sheath phenomenon in which they identified some very special cases which greatly simplified the sheath and allowed a closed solution to the problem. The most widely used application is for an electrostatic, or "Langmuir," probe in laboratory plasma. Although the Langmuir probe is physically simple (a biased wire) the theory describing its functional behavior and its current-voltage characteristic is extremely complex and, accordingly, a number of assumptions and approximations are used in the LMS model. These simplifications, correspondingly, place limits on the model's range of application. Adapting the LMS model to real-life conditions is the subject of numerous papers and dissertations. The Orbit-Motion Limited (OML) model that is widely used today is one of these adaptions that is a convenient means of calculating sheath effects. The OML equation for electron current collection by a positively biased body is simply: I is approximately equal to A x j(sub eo) x 2/v??(phi)(exp ½) where A is the area of the body and phi is the electric potential on the body with respect to the plasma. Since the Langmuir probe is a simple biased wire immersed in plasma, it is particularly tempting to use the OML equation in calculating the characteristics of the long, highly biased wires of an Electric Sail in the solar wind plasma. However, in order to arrive at the OML equation, a number of additional simplifying assumptions and approximations (beyond those made by Langmuir-Mott-Smith) are necessary. The OML equation is a good approximation when all conditions are met, but it would appear that the Electric Sail problem lies outside of the limits of applicability.

Protective effect of a lipid-based preparation from Mycobacterium smegmatis in a murine model of progressive pulmonary tuberculosis.

PubMed

García, Maria de los Angeles; Borrero, Reinier; Lanio, Maria E; Tirado, Yanely; Alvarez, Nadine; Puig, Alina; Aguilar, Alicia; Canet, Liem; Mata Espinoza, Dulce; Barrios Payán, Jorge; Sarmiento, María Elena; Hernández-Pando, Rogelio; Norazmi, Mohd-Nor; Acosta, Armando

2014-01-01

A more effective vaccine against tuberculosis (TB) is urgently needed. Based on its high genetic homology with Mycobacterium tuberculosis (Mtb), the nonpathogenic mycobacteria, Mycobacterium smegmatis (Ms), could be an attractive source of potential antigens to be included in such a vaccine. We evaluated the capability of lipid-based preparations obtained from Ms to provide a protective response in Balb/c mice after challenge with Mtb H37Rv strain. The intratracheal model of progressive pulmonary TB was used to assess the level of protection in terms of bacterial load as well as the pathological changes in the lungs of immunized Balb/c mice following challenge with Mtb. Mice immunized with the lipid-based preparation from Ms either adjuvanted with Alum (LMs-AL) or nonadjuvanted (LMs) showed significant reductions in bacterial load (P < 0.01) compared to the negative control group (animals immunized with phosphate buffered saline (PBS)). Both lipid formulations showed the same level of protection as Bacille Calmette and Guerin (BCG). Regarding the pathologic changes in the lungs, mice immunized with both lipid formulations showed less pneumonic area when compared with the PBS group (P < 0.01) and showed similar results compared with the BCG group. These findings suggest the potential of LMs as a promising vaccine candidate against TB.

Using the Leitz LMS 2000 for monitoring and improvement of an e-beam

NASA Astrophysics Data System (ADS)

Blaesing-Bangert, Carola; Roeth, Klaus-Dieter; Ogawa, Yoichi

1994-11-01

Kaizen--a continuously improving--is a philosophy lived in Japan which is also becoming more and more important in Western companies. To implement this philosophy in the semiconductor industry, a high performance metrology tool is essential to determine the status of production quality periodically. An important prerequisite for statistical process control is the high stability of the metrology tool over several months or years; the tool-induced shift should be as small as possible. The pattern placement metrology tool Leitz LMS 2000 has been used in a major European mask house for several years now to qualify masks within the tightest specifications and to monitor the MEBES III and its cassettes. The mask shop's internal specification for the long term repeatability of the pattern placement metrology tool is 19 nm instead of 42 nm as specified by the supplier of the tool. Then the process capability of the LMS 2000 over 18 months is represented by an average cpk value of 2.8 for orthogonality, 5.2 for x-scaling, and 3.0 for y-scaling. The process capability of the MEBES III and its cassettes was improved in the past years. For instance, 100% of the masks produced with a process tolerance of +/- 200 nm are now within this limit.

Assessing the relationship between surface urban heat islands and landscape patterns across climatic zones in China.

PubMed

Yang, Qiquan; Huang, Xin; Li, Jiayi

2017-08-24

The urban heat island (UHI) effect exerts a great influence on the Earth's environment and human health and has been the subject of considerable attention. Landscape patterns are among the most important factors relevant to surface UHIs (SUHIs); however, the relationship between SUHIs and landscape patterns is poorly understood over large areas. In this study, the surface UHI intensity (SUHII) is defined as the temperature difference between urban and suburban areas, and the landscape patterns are quantified by the urban-suburban differences in several typical landscape metrics (ΔLMs). Temperature and land-cover classification datasets based on satellite observations were applied to analyze the relationship between SUHII and ΔLMs in 332 cities/city agglomerations distributed in different climatic zones of China. The results indicate that SUHII and its correlations with ΔLMs are profoundly influenced by seasonal, diurnal, and climatic factors. The impacts of different land-cover types on SUHIs are different, and the landscape patterns of the built-up and vegetation (including forest, grassland, and cultivated land) classes have the most significant effects on SUHIs. The results of this study will help us to gain a deeper understanding of the relationship between the SUHI effect and landscape patterns.

Value of counting positive PHH3 cells in the diagnosis of uterine smooth muscle tumors

PubMed Central

Pang, Shu-Jie; Li, Cheng-Cheng; Shen, Yan; Liu, Yian-Zhu; Shi, Yi-Quan; Liu, Yi-Xin

2015-01-01

The diagnosis of uterine smooth muscle tumors including leiomyosarcomas (LMS), smooth muscle tumors of uncertain malignant potential (STUMP), bizarre (atypical) leiomyoma (BLM), mitotically active leiomyoma (MAL) and leiomyoma (LM) depends on a combination of microscopic features, such as mitoses, cytologic atypia, and coagulative tumor cell necrosis. However, a small number of these tumors still pose difficult diagnostic challenges. The assessment of accurate mitotic figures (MF) is one of the major parameters in the proper classification of uterine smooth muscle tumors. This assessment can be hampered by the presence of increased number of apoptotic bodies or pyknotic nuclei, which frequently mimic mitoses. Phospho-histone H3 (PHH3) is a recently described immunomarker specific for cells undergoing mitoses. In our study, we collected 132 cases of uterine smooth muscle tumors, including 26 LMSs, 16 STUMPs, 30 BLMs, 30 MALs and 30 LMs. We used mitosis specific marker PHH3 to count mitotic indexes (MI) of uterine smooth muscle tumors and compared with the mitotic indexes of hematoxylin and eosin (H&E). There is a positive correlation with the number of mitotic figures in H&E-stained sections and PHH3-stained sections (r=0.944, P<0.05). The ratio of PHH3-MI to H&E-MI has no statistically significant difference in each group except for LMs (P>0.05). The counting value of PHH3 in LMSs have significantly higher than STUMPs, BLMs, MALs and LMs (P<0.001) and the counting value of PHH3 is 1.5±0.5 times of the number of mitotic indexes in H&E. To conclude, our results show that counting PHH3 is a useful index in the diagnosis of uterine smooth muscle tumors and it can provide a more accurate index instead of the time-honored mitotic figure counts at a certain ratio. PMID:26191133

Using LMS tables to determine waist circumference and waist-to-height ratios in Colombian children and adolescents: the FUPRECOL study.

PubMed

Ramírez-Vélez, Robinson; Moreno-Jiménez, Javier; Correa-Bautista, Jorge Enrique; Martínez-Torres, Javier; González-Ruiz, Katherine; González-Jiménez, Emilio; Schmidt-RioValle, Jacqueline; Lobelo, Felipe; Garcia-Hermoso, Antonio

2017-07-11

Waist circumference (WC) and waist-to-height ratio (WHtR) are often used as indices predictive of central obesity. The aims of this study were: 1) to obtain smoothed centile charts and LMS tables for WC and WHtR among Colombian children and adolescents; 2) to evaluate the utility of these parameters as predictors of overweight and obesity. A cross-sectional study was conducted of a sample population of 7954 healthy Colombian schoolchildren [3460 boys and 4494 girls, mean age 12.8 (±2.3) years]. Weight, height, body mass index (BMI), WC and WHtR were measured, and percentiles were calculated using the LMS method (Box-Cox, median and coefficient of variation). Appropriate cut-off points of WC and WHtR for overweight and obesity, according to International Obesity Task Force definitions, were selected using receiver operating characteristic (ROC) analysis. The discriminating power of WC and WHtR is expressed as area under the curve (AUC). Reference values for WC and WHtR are presented. Mean WC increased and WHtR decreased with age for both genders. A moderate positive correlation was observed between WC and BMI (r = 0.756, P < 0.01) and between WHtR and BMI (r = 0.604, P < 0.01). ROC analysis revealed strong discrimination power in the identification of overweight and obesity for both measures in our sample population. Overall, WHtR was a slightly better predictor of overweight/obesity (AUC 95% CI 0.868-0.916) than WC (AUC 95% CI 0.862-0.904). This paper presents the first sex and age-specific WC and WHtR percentiles for Colombian children and adolescents aged 9.0-17.9 years. The LMS tables obtained, based on Colombian reference data, can be used as quantitative tools for the study of obesity and its comorbidities.

The biomechanical effect of transverse connectors use in a pre- and postlaminectomy model of the posterior cervical spine: an in vitro cadaveric study.

PubMed

Majid, Kamran; Gudipally, Manasa; Hussain, Mir; Moldavsky, Mark; Khalil, Saif

2011-12-15

An in vitro biomechanical study investigating the effect of transverse connectors on posterior cervical stabilization system in a laminectomy model. To evaluate the optimal design, number, and location of the transverse connectors in stabilizing long segment posterior instrumentation in the cervical spine. In the cervical spine, lateral mass screw (LMS) fixation is used for providing stability after decompression. Transverse connectors have been used to augment segmental posterior instrumentation. However, in the cervical region the optimal design, number, and the location of transverse connectors is not known. Seven fresh human cervicothoracic cadaveric spines (C2-T1) were tested by applying ±1.5 Nm moments in flexion (F), extension (E), lateral bending (LB), and axial rotation (AR). After testing the intact condition, LMS/rods were placed and then were tested with two different transverse connectors (top-loading connector [TL] and the head-to-head [HH] connector) in multiple levels, pre- and postlaminectomy (PL). LMS significantly reduced segmental motion by 77.2% in F, 75.6% in E, 86.6% in LB, and 86.1% in AR prelaminectomy and by 75.4% in F, 76% in E, 80.6% in LB, and 76.4% in AR postlaminectomy compared to intact (P < 0.05). Only in AR, PL constructs with HH connectors at C3 & C7, TL connectors at C4-C5 & C5-C6, and at C3-C4 & C6-C7 significantly reduced the range of motion by 12.9%, 11.9%, and 11.9%, respectively, compared to PL LMS (P < 0.05). No statistical significance was observed between TL connector and HH connector in all loading directions. The biomechanical advantage of transverse connectors is significant in AR, when using two connectors at the proximal and distal ends, compared to one connector. In a clinical setting, this data may guide surgeons on transverse connector configurations to consider during posterior cervical instrumentation.

Spatio-temporal aerosol particle distributions in the UT/LMS measured by the IAGOS-CARIBIC Observatory

NASA Astrophysics Data System (ADS)

Assmann, D. N.; Hermann, M.; Weigelt, A.; Martinsson, B. G.; Brenninkmeijer, C. A. M.; Rauthe-Schoech, A.; van Velthoven, P. J. F.; Boenisch, H.; Zahn, A.

2016-12-01

Submicrometer aerosol particles in the upper troposphere and lowermost stratosphere (UT/LMS) influence the Earth`s radiation budget directly and, more important, indirectly, by acting as cloud condensation nuclei and by changing trace gas concentrations through heterogeneous chemical processes. Since 1997, regular in situ UT/LMS aerosol particle measurements have been conducted by the Leibniz Institute for Tropospheric Research, Leipzig, Germany and the University of Lund, Sweden, using the the CARIBIC (now IAGOS-CARIBIC) observatory (www.caribic-atmospheric.com) onboard a passenger aircraft. Submicrometer aerosol particle number concentrations and the aerosol particle size distribution are measured using three condensation particle counters and one optical particle size spectrometer. Moreover, particle elemental composition is determined using an aerosol impactor sampler and post-flight ion beam analysis (PIXE, PESA) of the samples in the laboratory. Based on this unique data set, including meteorological analysis, we present representative spatio-temporal distributions of particle number, surface, volume, and elemental concentrations in an altitude of 8-12 km covering a large fraction of the northern hemisphere. We discuss the measured values in the different size regimes with respect to sources and sinks in different regions. Additionally, we calculated highly resolved latitudinal and longitudinal cross sections of the particle number size distribution, probability density functions and trends in particle number concentrations, but also in elemental composition, determined from our regular measurements over more than a decade. Moreover, we present the seasonality of particle number concentration in an equivelent latitude - potential temperature coordinate framework (see figure). The results are interpreted with respect to aerosol microphysics and transport using CARIBIC trace gas data like ozone and water vapour. The influence of clouds in the troposphere and the different stratosphere-troposphere-exchange processes are clearly visible. Besides providing information about UT/LMS aerosol particle sources, transport, and sinks, these distributions can be used to validate remote sensing instruments or global atmospheric aerosol models.

Spatio-temporal aerosol particle distributions in the UT/LMS measured by the IAGOS-CARIBIC Observatory

NASA Astrophysics Data System (ADS)

Assmann, Denise; Hermann, Markus; Weigelt, Andreas; Martinsson, Bengt; Brenninkmeijer, Carl; Rauthe-Schöch, Armin; van Velthoven, Peter; Bönisch, Harald; Zahn, Andreas

2017-04-01

Submicrometer aerosol particles in the upper troposphere and lowermost stratosphere (UT/LMS) influence the Earth`s radiation budget directly and, more important, indirectly, by acting as cloud condensation nuclei and by changing trace gas concentrations through heterogeneous chemical processes. Since 1997, regular in situ UT/LMS aerosol particle measurements have been conducted by the Leibniz Institute for Tropospheric Research, Leipzig, Germany and the University of Lund, Sweden, using the the CARIBIC (now IAGOS-CARIBIC) observatory (www.caribic-atmospheric.com) onboard a passenger aircraft. Submicrometer aerosol particle number concentrations and the aerosol particle size distribution are measured using three condensation particle counters and one optical particle size spectrometer. Moreover, particle elemental composition is determined using an aerosol impactor sampler and post-flight ion beam analysis (PIXE, PESA) of the samples in the laboratory. Based on this unique data set, including meteorological analysis, we present representative spatio-temporal distributions of particle number, surface, volume and elemental concentrations in an altitude of 8-12 km covering a large fraction of the northern hemisphere. We discuss the measured values in the different size regimes with respect to sources and sinks in different regions. Additionally, we calculated highly resolved latitudinal and longitudinal cross sections of the particle number size distribution, probability density functions and trends in particle number concentrations, but also in elemental composition, determined from our regular measurements over more than a decade. Moreover, we generated seasonal contour plots for particle number concentrations, the potential temperature, and the equivalent latitude. The results are interpreted with respect to aerosol microphysics and transport using CARIBIC trace gas data like ozone and water vapour. The influence of clouds in the troposphere and the different stratosphere-troposphere-exchange processes is clearly visible. Besides providing information about UT/LMS aerosol particle sources, transport, and sinks, these distributions can be used to validate remote sensing instruments or global atmospheric aerosol models.

Importance of granulometry on phase evolution and phase-to-phase relationships of experimentally burned impure limestones intended for production of hydraulic lime and/or natural cement

NASA Astrophysics Data System (ADS)

Kozlovcev, Petr; Přikryl, Richard; Přikrylová, Jiřina

2015-04-01

In contrast to modern ordinary Portland cement production from finely ground raw material blends, ancient burning of hydraulic lime was conducted by burning larger pieces of natural raw material. Due to natural variability of raw material composition, exploitation of different beds from even one formation can result the product with significantly different composition and/or properties. Prague basin (Neoproterozoic to pre-Variscan Palaeozoic of the central part of the Bohemian Massif - the so-called Barrandian area, Czech Republic) represents a classical example of the limestone-rich region with long-term history of limestone burning for quick lime and/or various types of hydraulic binders. Due to the fact that burning of natural hydraulic lime has been abandoned in this region at the turn of 19th/20th c., significant gap in knowledge on the behavior of various limestone types and on the influence of minor variance in composition on the quality of burned product is encountered. Moreover, the importance of employment of larger pieces of raw material for burning for the development of proper phase-to-phase relationships (i.e. development of hydraulic phases below sintering temperature at mutual contacts of minerals) has not been examined before. To fill this gap, a representative specimens of major limestone types from the Prague basin have been selected for experimental study: Upper Silurian limestone types (Přídolí and Kopanina Lms.), and Lower Devonian limestones (Radotín, Kotýs, Řeporyje, Dvorce-Prokop, and Zlíchov Lms.). Petrographic character of the experimental material was examined by polarizing microscopy, cathodoluminescence, scanning electron microscopy with an energy dispersive spectrometer (SEM-EDS), and X-ray diffraction (XRD) of insoluble residue. Based on the data from wet silicate analyses, modal composition of studied impure limestones was computed. Experimental raw material was burned in laboratory electric furnace at 1000 and 1200°C for 3 and/or 6 hours. Burned samples were examined by XRD for phase composition and by SEM-EDS for phase-to-phase relationships due to the burning. Based on our data it is evident that larnite-belite (dicalcium-silicate) is dominant phase in burned silica-rich limestones (represented by e.g. Dvorce-Prokop, Přídolí and/or Kopanina Lms.). In clay-rich limestones containing kaolinite and illite, gehlenite and other calcium aluminates and aluminosilicates were detected (represented by Kosoř, Řeporyje, and/or a portion of Dvorce-Prokop Lms.). Due to higher proportion of Fe-oxihydroxides in the Řeporyje Lms., brownmillerite (calcium aluminoferrite) forms as a typical minor phases during burning. Free-lime (plus its hydrated form - portlandite) makes dominant phase in limestones exhibiting low non-carbonate admixture (Kotýs and/or a portion of Kopanina Lms.). These results clearly demonstrate that presence of certain non-carbonate minerals governs formation of certain hydraulic phases in burned product, whilst mutual proportions of individual minerals in raw materials influence amount of newly formed phases.

AGHF, TRE and TVD experiment activity in the Spacelab during LMS-1 mission

NASA Image and Video Library

1996-07-09

STS078-396-015 (20 June - 7 July 1996) --- Payload specialist Jean-Jacques Favier, representing the French Space Agency (CNES), prepares a sample for the Advanced Gradient Heating Facility (AGHF) while wearing instruments that measure upper body movement. The Torso Rotation Experiment (TRE) complements other vestibular studies that measure differences in the way human beings react physically to their surroundings in microgravity. This is a typical Life and Microgravity Spacelab (LMS-1) mission scene, with several experiments being performed. Astronaut Susan J. Helms, payload commander, assists Favier in the AGHF preparations. Astronaut Richard M. Linnehan (bottom right), mission specialist, tests his muscle response with the Handgrip Dynamometer. Astronaut Thomas T. (Tom) Henricks (far background), mission commander, offers assistance.

Primary leiomyosarcoma of the maxilla: An investigative loom—report of a challenging case and review of literature

PubMed Central

Sandhu, Simarpreet Virk; Sodhi, S P S; Rai, Sachin; Bansal, Himanta

2014-01-01

Leiomyosarcoma (LMS) is a malignant neoplasm composed of cells showing distinct smooth muscle features. Majority of the tumors are located in the retroperitoneum, including the pelvis and the uterus but are rare in the oral and pharyngeal region. Intraorally, they are present as painless, lobulated, fixed masses of the submucosal tissues in middle-aged or older individuals. Lesions are usually slow growing and are less than 2 cm in diameter at the time of diagnosis. Here we report the clinico-pathological findings of a case of primary LMS of the maxilla in 63-year-old male patient with an emphasis on the judicious use of ancillary diagnostic modalities to arrive at a definitive diagnosis. PMID:25949006

Space Shuttle Projects

NASA Image and Video Library

1996-04-01

The crew assigned to the STS-78 mission included (seated left to right) Terrence T. (Tom) Henricks, commander; and Kevin R. Kregel, pilot. Standing, left to right, are Jean-Jacques Favier (CNES), payload specialist; Richard M. Linneham, mission specialist; Susan J. Helms, payload commander; Charles E. Brady, mission specialist; and Robert Brent Thirsk (CSA). Launched aboard the Space Shuttle Columbia on June 20, 1996 at 10:49:00 am (EDT), the STS-78 mission’s primary payloads was the Life and Microgravity Spacelab (LMS). Five space agencies (NASA/USA, European Space Agency/Europe (ESA), French Space Agency/France, Canadian Space Agency /Canada, and Italian Space Agency/Italy) along with research scientists from 10 countries worked together on the design, development and construction of the LMS.

Demultiplexing based on frequency-domain joint decision MMA for MDM system

NASA Astrophysics Data System (ADS)

Caili, Gong; Li, Li; Guijun, Hu

2016-06-01

In this paper, we propose a demultiplexing method based on frequency-domain joint decision multi-modulus algorithm (FD-JDMMA) for mode division multiplexing (MDM) system. The performance of FD-JDMMA is compared with frequency-domain multi-modulus algorithm (FD-MMA) and frequency-domain least mean square (FD-LMS) algorithm. The simulation results show that FD-JDMMA outperforms FD-MMA in terms of BER and convergence speed in the cases of mQAM (m=4, 16 and 64) formats. And it is also demonstrated that FD-JDMMA achieves better BER performance and converges faster than FD-LMS in the cases of 16QAM and 64QAM. Furthermore, FD-JDMMA maintains similar computational complexity as the both equalization algorithms.

COIS, Favier works with experiment assisted by Helms during LMS-1 mission

NASA Image and Video Library

1996-07-09

STS078-398-032 (20 June - 7 July 1996) --- Astronaut Susan J. Helms, payload commander, measures the distance between Jean-Jacques Favier’s head and the luminous torque, used for the Canal and Otolith Interaction Study (COIS) on the Life and Microgravity Spacelab (LMS-1) mission. Favier, representing the French Space Agency (CNES), is one of two international payload specialists on the almost-17-day flight. This view shows the Voluntary Head Movement (VHM) segment of the experiment. The VHM is meant to characterize how the coordination of head and eye movement changes as a result of spaceflight. Since most vestibular functions are influenced by gravity, the COIS experiment is meant to measure response differences in microgravity.

Implementation of a platform dedicated to the biomedical analysis terminologies management

PubMed Central

Cormont, Sylvie; Vandenbussche, Pierre-Yves; Buemi, Antoine; Delahousse, Jean; Lepage, Eric; Charlet, Jean

2011-01-01

Background and objectives. Assistance Publique - Hôpitaux de Paris (AP-HP) is implementing a new laboratory management system (LMS) common to the 12 hospital groups. First step to this process was to acquire a biological analysis dictionary. This dictionary is interfaced with the international nomenclature LOINC, and has been developed in collaboration with experts from all biological disciplines. In this paper we describe in three steps (modeling, data migration and integration/verification) the implementation of a platform for publishing and maintaining the AP-HP laboratory data dictionary (AnaBio). Material and Methods. Due to data complexity and volume, setting up a platform dedicated to the terminology management was a key requirement. This is an enhancement tackling identified weaknesses of previous spreadsheet tool. Our core model allows interoperability regarding data exchange standards and dictionary evolution. Results. We completed our goals within one year. In addition, structuring data representation has lead to a significant data quality improvement (impacting more than 10% of data). The platform is active in the 21 hospitals of the institution spread into 165 laboratories. PMID:22195205

Early breast tumor and late SARS detections using space-variant multispectral infrared imaging at a single pixel

NASA Astrophysics Data System (ADS)

Szu, Harold H.; Buss, James R.; Kopriva, Ivica

2004-04-01

We proposed the physics approach to solve a physical inverse problem, namely to choose the unique equilibrium solution (at the minimum free energy: H= E - ToS, including the Wiener, l.m.s E, and ICA, Max S, as special cases). The "unsupervised classification" presumes that required information must be learned and derived directly and solely from the data alone, in consistence with the classical Duda-Hart ATR definition of the "unlabelled data". Such truly unsupervised methodology is presented for space-variant imaging processing for a single pixel in the real world case of remote sensing, early tumor detections and SARS. The indeterminacy of the multiple solutions of the inverse problem is regulated or selected by means of the absolute minimum of isothermal free energy as the ground truth of local equilibrium condition at the single-pixel foot print.

Lunar Meteorites and Implications for Compositional Remote Sensing of the Lunar Surface

NASA Technical Reports Server (NTRS)

Korotev, R. L.

1999-01-01

Lunar meteorites (LMs) are rocks found on Earth that were ejected from the Moon by impact of an asteroidal meteoroid. Three factors make the LMs important to remote-sensing studies: (1) Most are breccias composed of regolith or fragmental material; (2) all are rocks that resided (or breccias composed of material that resided) in the upper few meters of the Moon prior to launch and (3) most apparently come from areas distant from the Apollo sites. How Many Lunar Locations? At this writing (June 1999), there are 18 known lunar meteorite specimens. When unambiguous cases of terrestrial pairing are considered, the number of actual LMs reduces to 13. (Terrestrial pairing is when a single piece of lunar rock entered Earth's atmosphere, but multiple fragments were produced because the meteoroid broke apart on entry, upon hitting the ground or ice, or while being transported through the ice.) We have no reason to believe that LMs preferentially derive from any specific region(s) of the Moon; i.e., we believe that they are samples from random locations. However, we do not know how many different locations are represented by the LMs; mathematically, it could be as few as 1 or as many as 13. The actual maximum is < 13 because in some cases a single impact appears to have yielded more than one LM. Yamato 793169 and Asuka 881757 are considered "source-crater paired" or "launch paired" because they are compositionally and petrographically similar to each other and distinct from the others, and both have similar cosmic-ray exposure (CRE) histories. The same can be said of QUE 94281 and Y 793274. Thus the 13 meteorites probably represent a maximum of 11 locations on the Moon. The minimum number of likely source craters is debated and in flux as new data for different isotopic systems are obtained. Conservatively, considering CRE data only, a minimum of about 5 impacts is required. Compositional and petrographic data offer only probabilistic constraints. An extreme, but not unreasonable viewpoint, is that such data offer no constraint. For example, if one were to cut up the Apollo 17 landing site (which was selected for its diversity) into softball-sized pieces, some of those pieces (e.g., sample 70135) would be crystalline mare basalts like Y 793169 whereas others (e.g., sample 73131 would be feldspathic regolith breccias like MAC 88104/ 88105. However, nature is not so devious. Warren argues that LMs come from craters of only a few kilometers in diameter. If so, even though CRE data allow, for example, that ALHA 81005 and Y 791197) were launched simultaneously from the same crater, the probability is nevertheless low because the two meteorites are compositionally and mineralogically distinct. Thus, within the allowed range (5-11) for the number of locations represented by the LMs, values at the high end of the range are probably more likely. Mare Meteorites: Three LMs consist almost entirely of mare basalt. Two, Y 793169 and Asuka 881757, are unbrecciated, low-Ti, crystalline rocks that are compositionally and mineralogically similar (but not identical) to each other; they probably derive from a single lunar-mare location. The third, EET 87521/96008, is a fragmental breccia consisting predominantly of VLT mare basalt. Thus, these LMs probably represent only two lunar mare locations. The basaltic LMs have mineral and bulk compositions distinct from Apollo mare basalts. The petrography of Calcalong Creek has not been described in detail, but compositionally it is unique in that it corresponds to a mixture (breccia) of about one-half feldspathic material (i.e., the mean composition of the feldspathic lunar meteorites, below), one-fourth KREEP norite, one-fourth VLT mare basalt (like EET 87521), and 1% CI chondrite. With 4 micro g/g Th and correspondingly high concentrations of other incompatible elements, it is the only lunar meteorite that is likely to have come from within the Procellarum KREEP Terrane (PKT). Yamato 793274 and QUE 94281 are together distinct in being fragmental breccias containing subequal parts of feldspathic highland material and VLT mare basalt. Jolliff et al. estimate a mare to highland ratio of 54:46 for QUE 94281 and 62:38 for Y 793274; this difference is well within the range observed for soils collected only centimeters apart (in cores) at interface site like Apollo 15 and 17 [11]. Although the two meteorites were found on opposite sides of Antarctica, they are probably launch-paired. The strongest evidence is that the pyroclastic glass spherules that occur in both are of two compositional groups and the two groups are essentially the same in both meteorites. Yamato 791197 is nominally a feldspathic lunar meteorite (below), but among FLMs, it probably contains the highest abundance of clasts and glasses of mare derivation. As a consequence, its composition is at the high-Fe, low-Mg end of the range for FLMs and is not included in the FLM average of Table 1. Its composition is consistent with about 10% mare-derived material. Similarly, the two small (Y 82) pieces of Y 82192/82193186032 are more mafic than the large (Y 86) piece, probably as a result of about 7% mare-derived material. All Apollo missions went to areas in or near the PKT, and, consequently, all Apollo regolith samples are contaminated with Th-rich material from the PKT. At the nominally "typical" highland site, Apollo 16, about 30% of the regolith (<1-mm fines) is Th-rich ejecta from the Imbrium impact and about 6% is mare material probably derived from mare basins. Thus Apollo 16 regolith is not typical of the highlands. Among Apollo rocks, the compositions of the FLMs correspond most closely to the feldspathic granulitic breccias of Apollo 16 and 17. (Additional information is contained in original)

[Growth references for weight and height for Argentinian girls and boys from birth to maturity: incorporation of data from the World Health Organisation from birth to 2 years and calculation of new percentiles and LMS values].

PubMed

Lejarraga, Horacio; del Pino, Mariana; Fano, Virginia; Caino, Silvia; Cole, Timothy J

2009-04-01

Argentine growth references have been widely used by paediatricians in the country for the last 20 years. Two main difficulties were detected during this period: the lack of data on breast-fed children in the first months of age, and problems in the calculation of "z" scores. On these basis, local data on weight and height during the first two years of life were replaced by data from the longitudinal international study recently carried out by WHO. L, M and S values were obtained from the original percentile data for ages 2 to maturity, and smoothed with cubic splines. Selected percentiles for weight and height from birth to maturity were then re-calculated using LMS values. Charts were designed in two formats: birth to maturity and birth to 6.0 years. Now, users can calculate "z" scores automatically at the new site provided by the Department of Growth and Development, Hospital Garrahan, which enables the use of the LMS growth programme. We have also incorporated into the new charts, percentiles of the age of attaining menarche and Tanner s stage II of breast, genitalia and pubic hair for Argentine children. We think the new references represent an improvement in the assessment of growth in our country.

Comparison of Five System Identification Algorithms for Rotorcraft Higher Harmonic Control

NASA Technical Reports Server (NTRS)

Jacklin, Stephen A.

1998-01-01

This report presents an analysis and performance comparison of five system identification algorithms. The methods are presented in the context of identifying a frequency-domain transfer matrix for the higher harmonic control (HHC) of helicopter vibration. The five system identification algorithms include three previously proposed methods: (1) the weighted-least- squares-error approach (in moving-block format), (2) the Kalman filter method, and (3) the least-mean-squares (LMS) filter method. In addition there are two new ones: (4) a generalized Kalman filter method and (5) a generalized LMS filter method. The generalized Kalman filter method and the generalized LMS filter method were derived as extensions of the classic methods to permit identification by using more than one measurement per identification cycle. Simulation results are presented for conditions ranging from the ideal case of a stationary transfer matrix and no measurement noise to the more complex cases involving both measurement noise and transfer-matrix variation. Both open-loop identification and closed- loop identification were simulated. Closed-loop mode identification was more challenging than open-loop identification because of the decreasing signal-to-noise ratio as the vibration became reduced. The closed-loop simulation considered both local-model identification, with measured vibration feedback and global-model identification with feedback of the identified uncontrolled vibration. The algorithms were evaluated in terms of their accuracy, stability, convergence properties, computation speeds, and relative ease of implementation.

Improving the Response of Accelerometers for Automotive Applications by Using LMS Adaptive Filters

PubMed Central

Hernandez, Wilmar; de Vicente, Jesús; Sergiyenko, Oleg; Fernández, Eduardo

2010-01-01

In this paper, the least-mean-squares (LMS) algorithm was used to eliminate noise corrupting the important information coming from a piezoresisitive accelerometer for automotive applications. This kind of accelerometer is designed to be easily mounted in hard to reach places on vehicles under test, and they usually feature ranges from 50 to 2,000 g (where is the gravitational acceleration, 9.81 m/s2) and frequency responses to 3,000 Hz or higher, with DC response, durable cables, reliable performance and relatively low cost. However, here we show that the response of the sensor under test had a lot of noise and we carried out the signal processing stage by using both conventional and optimal adaptive filtering. Usually, designers have to build their specific analog and digital signal processing circuits, and this fact increases considerably the cost of the entire sensor system and the results are not always satisfactory, because the relevant signal is sometimes buried in a broad-band noise background where the unwanted information and the relevant signal sometimes share a very similar frequency band. Thus, in order to deal with this problem, here we used the LMS adaptive filtering algorithm and compare it with others based on the kind of filters that are typically used for automotive applications. The experimental results are satisfactory. PMID:22315542

Hybrid feedforward-feedback active noise reduction for hearing protection and communication.

PubMed

Ray, Laura R; Solbeck, Jason A; Streeter, Alexander D; Collier, Robert D

2006-10-01

A hybrid active noise reduction (ANR) architecture is presented and validated for a circumaural earcup and a communication earplug. The hybrid system combines source-independent feedback ANR with a Lyapunov-tuned leaky LMS filter (LyLMS) improving gain stability margins over feedforward ANR alone. In flat plate testing, the earcup demonstrates an overall C-weighted total noise reduction of 40 dB and 30-32 dB, respectively, for 50-800 Hz sum-of-tones noise and for aircraft or helicopter cockpit noise, improving low frequency (<100 Hz) performance by up to 15 dB over either control component acting individually. For the earplug, a filtered-X implementation of the LyLMS accommodates its nonconstant cancellation path gain. A fast time-domain identification method provides a high-fidelity, computationally efficient, infinite impulse response cancellation path model, which is used for both the filtered-X implementation and communication feedthrough. Insertion loss measurements made with a manikin show overall C-weighted total noise reduction provided by the ANR earplug of 46-48 dB for sum-of-tones 80-2000 Hz and 40-41 dB from 63 to 3000 Hz for UH-60 helicopter noise, with negligible degradation in attenuation during speech communication. For both hearing protectors, a stability metric improves by a factor of 2 to several orders of magnitude through hybrid ANR.

ZnS/diamond composite coatings for infrared transmission applications formed by the aerosol deposition method

NASA Astrophysics Data System (ADS)

Johnson, Scooter D.; Kub, Fritz J.; Eddy, Charles R.

2013-06-01

The deposition of nano-crystalline ZnS/diamond composite protective coatings on silicon, sapphire, and ZnS substrates, as a preliminary step to coating infrared transparent ZnS substrates from powder mixtures by the aerosol deposition method is presented. Advantages of the aerosol deposition method include the ability to form dense, nanocrystalline lms up to hundreds of microns thick at room temperature and at a high deposition rate on a variety of substrates. Deposition is achieved by creating a pressure gradient that accelerates micrometer- scale particles in an aerosol to high velocity. Upon impact with the target substrate the particles fracture and embed. Continued deposition forms the thick compacted lm. Deposition from an aerosolized mixture of ZnS and diamond powders onto all targets results in linear trend from apparent sputter erosion of the substrate at 100% diamond to formation of a lm with increasing fractions of ZnS. The crossover from abrasion to lm formation on sapphire occurs above about 50% ZnS and a mixture of 90% ZnS and 10% diamond forms a well-adhered lm of about 0.7 μm thickness at a rate of 0.14 μm/min. Resulting lms are characterized by scanning electron microscopy, pro lometry, infrared transmission spectroscopy, and x-ray photoemission spectroscopy. These initial lms mark progress toward the future goal of coating ZnS substrates for abrasion resistance.

New reference charts for testicular volume in Dutch children and adolescents allow the calculation of standard deviation scores.

PubMed

Joustra, Sjoerd D; van der Plas, Evelyn M; Goede, Joery; Oostdijk, Wilma; Delemarre-van de Waal, Henriette A; Hack, Wilfried W M; van Buuren, Stef; Wit, Jan M

2015-06-01

Accurate calculations of testicular volume standard deviation (SD) scores are not currently available. We constructed LMS-smoothed age-reference charts for testicular volume in healthy boys. The LMS method was used to calculate reference data, based on testicular volumes from ultrasonography and Prader orchidometer of 769 healthy Dutch boys aged 6 months to 19 years. We also explored the association between testicular growth and pubic hair development, and data were compared to orchidometric testicular volumes from the 1997 Dutch nationwide growth study. The LMS-smoothed reference charts showed that no revision of the definition of normal onset of male puberty - from nine to 14 years of age - was warranted. In healthy boys, the pubic hair stage SD scores corresponded with testicular volume SD scores (r = 0.394). However, testes were relatively small for pubic hair stage in Klinefelter's syndrome and relatively large in immunoglobulin superfamily member 1 deficiency syndrome. The age-corrected SD scores for testicular volume will aid in the diagnosis and follow-up of abnormalities in the timing and progression of male puberty and in research evaluations. The SD scores can be compared with pubic hair SD scores to identify discrepancies between cell functions that result in relative microorchidism or macroorchidism. ©2015 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

Comparing model-based adaptive LMS filters and a model-free hysteresis loop analysis method for structural health monitoring

NASA Astrophysics Data System (ADS)

Zhou, Cong; Chase, J. Geoffrey; Rodgers, Geoffrey W.; Xu, Chao

2017-02-01

The model-free hysteresis loop analysis (HLA) method for structural health monitoring (SHM) has significant advantages over the traditional model-based SHM methods that require a suitable baseline model to represent the actual system response. This paper provides a unique validation against both an experimental reinforced concrete (RC) building and a calibrated numerical model to delineate the capability of the model-free HLA method and the adaptive least mean squares (LMS) model-based method in detecting, localizing and quantifying damage that may not be visible, observable in overall structural response. Results clearly show the model-free HLA method is capable of adapting to changes in how structures transfer load or demand across structural elements over time and multiple events of different size. However, the adaptive LMS model-based method presented an image of greater spread of lesser damage over time and story when the baseline model is not well defined. Finally, the two algorithms are tested over a simpler hysteretic behaviour typical steel structure to quantify the impact of model mismatch between the baseline model used for identification and the actual response. The overall results highlight the need for model-based methods to have an appropriate model that can capture the observed response, in order to yield accurate results, even in small events where the structure remains linear.

Middle School Engineering Problem Solving Using Traditional vs. e-PBL Module Instruction

NASA Astrophysics Data System (ADS)

Baele, Loren C.

This multiple methods (Denzin, 1978) study investigated two instructional approaches, traditional module and electronic Problem-Based Learning instruction (e-PBL), used within a middle school engineering classroom focused on the variables of engagement, content knowledge, student self-assessment and teacher assessment of problem solving solutions. A non-equivalent group quasi-experimental research design (Creswell, 2015) was used on middle school students (N = 100) between those that received traditional module instruction (n = 51) and e-PBL instruction (n = 49). The qualitative approach of triangulation (Jick, 1979) was used to identify emergent themes for both between and within methods of data analysis on student engagement survey responses, two days of field observations notes, and six student interview transcripts. The quantitative results identified that students who received e-PBL instruction self-reported significantly greater engagement than those who received traditional module instruction. Further, there was a significant interaction effect between engineering content knowledge by group and gender as males who received e-PBL instruction had greater growth of content knowledge scores than males receiving traditional instruction, while females who received traditional instruction had greater growth of content knowledge scores than females in the e-PBL group. Through triangulation of the qualitative data, the emergent themes of the study suggest that hands-on learning produces higher levels of reported engagement independent of instructional method. The emergence of problem solving fatigue developed when both study groups reported a decline in engagement when entering into the final phase of the quantitative study suggesting that too many complex, ill-structured problems in rapid succession may negatively impact student engagement. Although females within the treatment group were most engaged, they did not achieve the knowledge growth of the females in the control group, who were the least engaged. Males presented with e-PBL instruction not only had better engagement, they had the greatest content knowledge growth of any group. Females were likely to have a greater negative difference between self-assessment scores and teacher assessment scores, while males self-assessed themselves closer to the teacher assessment score. Challenges to e-PBL implementation were identified including time, teacher training, and the strict school schedule. A learning management system (LMS) was found to effectively facilitate an e-PBL learning environment.

Vacancy-mediated fcc/bcc phase separation in Fe 1-xNi x ultrathin films

DOE PAGES

Mentes, T. O.; Stojic, N.; Vescovo, E.; ...

2016-08-01

The phase separation occurring in Fe-Ni thin lms near the Invar composition is studied by using high resolution spectromicroscopy techniques and density functional theory calculations. Annealed at temperatures around 300 C, Fe 0.70Ni 0.30 lms on W(110) break into micron-sized bcc and fcc domains with compositions in agreement with the bulk Fe-Ni phase diagram. Ni is found to be the di using species in forming the chemical heterogeneity. The experimentally-determined energy barrier of 1.59 0.09 eV is identi ed as the vacancy formation energy via density functional theory calculations. Thus, the principal role of the surface in the phase separationmore » process is attributed to vacancy creation without interstitials.« less

Volterra series based blind equalization for nonlinear distortions in short reach optical CAP system

NASA Astrophysics Data System (ADS)

Tao, Li; Tan, Hui; Fang, Chonghua; Chi, Nan

2016-12-01

In this paper, we propose a blind Volterra series based nonlinear equalization (VNLE) with low complexity for the nonlinear distortion mitigation in short reach optical carrierless amplitude and phase (CAP) modulation system. The principle of the blind VNLE is presented and the performance of its blind adaptive algorithms including the modified cascaded multi-mode algorithm (MCMMA) and direct detection LMS (DD-LMS) are investigated experimentally. Compared to the conventional VNLE using training symbols before demodulation, it is performed after matched filtering and downsampling, so shorter memory length is required but similar performance improvement is observed. About 1 dB improvement is observed at BER of 3.8×10-3 for 40 Gb/s CAP32 signal over 40 km standard single mode fiber.

Enhanced performance of visible light communication employing 512-QAM N-SC-FDE and DD-LMS.

PubMed

Wang, Yuanquan; Huang, Xingxing; Zhang, Junwen; Wang, Yiguang; Chi, Nan

2014-06-30

In this paper, a novel hybrid time-frequency adaptive equalization algorithm based on a combination of frequency domain equalization (FDE) and decision-directed least mean square (DD-LMS) is proposed and experimentally demonstrated in a Nyquist single carrier visible light communication (VLC) system. Adopting this scheme, as well with 512-ary quadrature amplitude modulation (512-QAM) and wavelength multiplexing division (WDM), an aggregate data rate of 4.22-Gb/s is successfully achieved employing a single commercially available red-green-blue (RGB) light emitting diode (LED) with low bandwidth. The measured Q-factors for 3 wavelength channels are all above the Q-limit. To the best of our knowledge, this is the highest data rate ever achieved by employing a commercially available RGB-LED.

Indoor visible light communication with smart lighting technology

NASA Astrophysics Data System (ADS)

Das Barman, Abhirup; Halder, Alak

2017-02-01

An indoor visible-light communication performance is investigated utilizing energy efficient white light by 2D LED arrays. Enabled by recent advances in LED technology, IEEE 802.15.7 standardizes high-data-rate visible light communication and advocates for colour shift keying (CSK) modulation to overcome flicker and to support dimming. Voronoi segmentation is employed for decoding N-CSK constellation which has superior performance compared to other existing decoding methods. The two chief performance degrading effects of inter-symbol interference and LED nonlinearity is jointly mitigated using LMS post equalization at the receiver which improves the symbol error rate performance and increases field of view of the receiver. It is found that LMS post equalization symbol at 250MHz offers 7dB SNR improvement at SER10-6

Biomechanical analysis comparing three C1-C2 transarticular screw salvaging fixation techniques.

PubMed

Elgafy, Hossein; Potluri, Tejaswy; Goel, Vijay K; Foster, Scott; Faizan, Ahmad; Kulkarni, Nikhil

2010-02-15

This is an in vitro biomechanical study. To compare the biomechanical stability of the 3 C1-C2 transarticular screw salvaging fixation techniques. Stabilization of the atlantoaxial complex is a challenging procedure because of its complicated anatomy. Many posterior stabilization techniques of the atlantoaxial complex have been developed with C1-C2 transarticular screw fixation been the current gold standard. The drawback of using the transarticular screws is that it has a potential risk of vertebral artery injury due to a high riding transverse foramen of C2 vertebra, and screw malposition. In such cases, it is not recommended to proceed with inserting the contralateral transarticular screw and the surgeon should find an alternative to fix the contralateral side. Many studies are available comparing different atlantoaxial stabilization techniques, but none of them compared the techniques to fix the contralateral side while using the transarticular screw on one side. The current options are C1 lateral mass screw and short C2 pedicle screw or C1 lateral mass screw and C2 intralaminar screw, or C1-C2 sublaminar wire. Nine fresh human cervical spines with intact ligaments (C0-C4) were subjected to pure moments in the 6 loading directions. The resulting spatial orientations of the vertebrae were recorded using an Optotrak 3-dimensional Motion Measurement System. Measurements were made sequentially for the intact spine after creating type II odontoid fracture and after stabilization with unilateral transarticular screw placement across C1-C2 (TS) supplemented with 1 of the 3 transarticular salvaging techniques on the contralateral side; C1 lateral mass screw and C2 pedicle screw (TS+C1LMS+C2PS), C1 lateral mass and C2 intralaminar screw (TS+C1LMS+C2ILS), or sublaminar wire (TS + wire). The data indicated that all the 3 stabilization techniques significantly decreased motion when compared to intact in all the loading cases (left/right lateral bending, left/right axial rotation, flexion) except extension. All the 3 instrumented specimens were equally stable in extension/flexion and lateral bending modes. TS+C1LMS+C2PS was equivalent to TS+C1LMS+C2ILS (P > 0.05) and superior to TS + wire in axial rotation (P < 0.05). Also, TS+C1LMS+C2ILS was superior to TS + wire in axial rotation (P < 0.05). Fixation of atlantoaxial complex using unilateral transarticular screw supplemented with contralateral C1 lateral mass and C2 intralaminar screws is biomechanically equivalent to C1 lateral mass and C2 pedicle screws and both are biomechanically superior to C1-C2 sublaminar wire in axial rotation.

Laser-based mass spectrometry for in situ chemical composition analysis of planetary surfaces

NASA Astrophysics Data System (ADS)

Frey, Samira; Neuland, Maike B.; Grimaudo, Valentine; Moreno-García, Pavel; Riedo, Andreas; Tulej, Marek; Broekmann, Peter; Wurz, Peter

2016-04-01

Mass spectrometry is an important analytical technique in space research. The chemical composition of planetary surface material is a key scientific question on every space mission to a planet, moon or asteroid. Chemical composition measurements of rocky material on the surface are of great importance to understand the origin and evolution of the planetary body.[1] A miniature laser ablation/ionisation reflectron- type time-of-flight mass spectrometer (instrument name LMS) was designed and built at the University of Bern for planetary research.[2] Despite its small size and light weight, the LMS instrument still maintains the same capabilities as large laboratory systems, which makes it suitable for its application on planetary space missions.[3-5] The high dynamic range of about eight orders of magnitude, high lateral (μm-level) and vertical (sub-nm level) resolution and high detection sensitivity for almost all elements (10 ppb, atomic fraction) make LMS a versatile instrument for various applications. LMS is a suitable instrument for in situ measurements of elemental and isotope composition with high precision and accuracy. Measurements of Pb- isotope abundances can be used for dating of planetary material. Measurements of bio-relevant elements allow searching for past or present life on a planetary surface. The high spatial resolution, both in lateral and vertical direction, is of considerable interest, e.g. for analysis of inhomogeneous, extraterrestrial samples as well as weathering processes of planetary material. References [1] P. Wurz, D. Abplanalp, M. Tulej, M. Iakovleva, V.A. Fernandes, A. Chumikov, and G. Managadze, "Mass Spectrometric Analysis in Planetary Science: Investigation of the Surface and the Atmosphere", Sol. Sys. Res., 2012, 46, 408. [2] U. Rohner, J.A. Whitby, P. Wurz, "A miniature laser ablation time of flight mass spectrometer for in situ planetary exploration" Meas. Sci. Tch., 2003, 14, 2159. [3] M. Tulej, A. Riedo, M.B. Neuland, S. Meyer, P. Wurz, N. Thomas, V. Grimaudo, P. Moreno-García, P. Broekmann, A. Neubeck and M. Ivarsson, "CAMAM: A miniature laser ablation ionisation mass spectrometer and microscope-camera system for in situ investigation of the composition and morphology of extraterrestrial materials", Geostand. Geoanal. Res., 2014, 38, 441. [4] A. Riedo, M. Neuland, S. Meyer, M. Tulej and P. Wurz, "Coupling of LMS with a fs-laser ablation ion source: elemental and isotope composition measurements", J. Anal. At. Spectrom., 2013, 28, 1256. [5] A. Riedo, S. Meyer, B. Heredia, M. Neuland, A. Bieler, M. Tulej, I. Leya, M. Iakovleva, K. Mezger and P. Wurz, "Highly accurate isotope composition measurements by a miniature laser ablation mass spectrometer designed for in situ investigations on planetary surfaces", Planet. Space Sci., 2013, 87, 1.

May 2012 Groundwater and Surface Water Sampling at the Rio Blanco, Colorado, Site (Data Validation Package)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hutton, Rick

2012-12-01

Annual sampling was conducted at the Rio Blanco, Colorado, site for the Long-Term Hydrologic Monitoring Program May 9-10, 2012, to monitor groundwater and surface water for potential radionuclide contamination. Sampling and analyses were conducted as specified in Sampling and Analysis Plan for the U.S. Department of Energy Office of Legacy Management Sites (LMS/PRO/S04351, continually updated). A duplicate sample was collected from location Johnson Artesian WL. Samples were analyzed for gamma-emitting radionuclides by high-resolution gamma spectrometry and for tritium using the conventional and enrichment methods. Results of this monitoring at the Rio Blanco site demonstrate that groundwater and surface water outsidemore » the site boundaries have not been affected by project-related contaminants.« less

Accurate and Simple Screw Insertion Procedure With Patient-Specific Screw Guide Templates for Posterior C1-C2 Fixation.

PubMed

Sugawara, Taku; Higashiyama, Naoki; Kaneyama, Shuichi; Sumi, Masatoshi

2017-03-15

Prospective clinical trial of the screw insertion method for posterior C1-C2 fixation utilizing the patient-specific screw guide template technique. To evaluate the efficacy of this method for insertion of C1 lateral mass screws (LMS), C2 pedicle screws (PS), and C2 laminar screws (LS). Posterior C1LMS and C2PS fixation, also known as the Goel-Harms method, can achieve immediate rigid fixation and high fusion rate, but the screw insertion carries the risk of injury to neuronal and vascular structures. Dissection of venous plexus and C2 nerve root to confirm the insertion point of the C1LMS may also cause problems. We have developed an intraoperative screw guiding method using patient-specific laminar templates. Preoperative bone images of computed tomography (CT) were analyzed using three-dimensional (3D)/multiplanar imaging software to plan the trajectories of the screws. Plastic templates with screw guiding structures were created for each lamina using 3D design and printing technology. Three types of templates were made for precise multistep guidance, and all templates were specially designed to fit and lock on the lamina during the procedure. Surgery was performed using this patient-specific screw guide template system, and placement of the screws was postoperatively evaluated using CT. Twelve patients with C1-C2 instability were treated with a total of 48 screws (24 C1LMS, 20 C2PS, 4 C2LS). Intraoperatively, each template was found to exactly fit and lock on the lamina and screw insertion was completed successfully without dissection of the venous plexus and C2 nerve root. Postoperative CT showed no cortical violation by the screws, and mean deviation of the screws from the planned trajectories was 0.70 ± 0.42 mm. The multistep, patient-specific screw guide template system is useful for intraoperative screw navigation in posterior C1-C2 fixation. This simple and economical method can improve the accuracy of screw insertion, and reduce operation time and radiation exposure of posterior C1-C2 fixation surgery. 3.

Long-term adaptive evolution of Leuconostoc mesenteroides for enhancement of lactic acid tolerance and production.

PubMed

Ju, Si Yeon; Kim, Jin Ho; Lee, Pyung Cheon

2016-01-01

Lactic acid has been approved by the United States Food and Drug Administration as Generally Regarded As Safe (GRAS) and is commonly used in the cosmetics, pharmaceutical, and food industries. Applications of lactic acid have also emerged in the plastics industry. Lactic acid bacteria (LAB), such as Leuconostoc and Lactobacillus , are widely used as lactic acid producers for food-related and biotechnological applications. Nonetheless, industrial mass production of lactic acid in LAB is a challenge mainly because of growth inhibition caused by the end product, lactic acid. Thus, it is important to improve acid tolerance of LAB to achieve balanced cell growth and a high titer of lactic acid. Recently, adaptive evolution has been employed as one of the strategies to improve the fitness and to induce adaptive changes in bacteria under specific growth conditions, such as acid stress. Wild-type Leuconostoc mesenteroides was challenged long term with exogenously supplied lactic acid, whose concentration was increased stepwise (for enhancement of lactic acid tolerance) during 1 year. In the course of the adaptive evolution at 70 g/L lactic acid, three mutants (LMS50, LMS60, and LMS70) showing high specific growth rates and lactic acid production were isolated and characterized. Mutant LMS70, isolated at 70 g/L lactic acid, increased d-lactic acid production up to 76.8 g/L, which was twice that in the wild type (37.8 g/L). Proteomic, genomic, and physiological analyses revealed that several possible factors affected acid tolerance, among which a mutation of ATPase ε subunit (involved in the regulation of intracellular pH) and upregulation of intracellular ammonia, as a buffering system, were confirmed to contribute to the observed enhancement of tolerance and production of d-lactic acid. During adaptive evolution under lethal stress conditions, the fitness of L. mesenteroides gradually increased to accumulate beneficial mutations according to the stress level. The enhancement of acid tolerance in the mutants contributed to increased production of d-lactic acid. The observed genetic and physiological changes may systemically help remove protons and retain viability at high lactic acid concentrations.

Bridging the gap between informatics and medicine upon medical school entry: Implementing a course on the Applicative Use of ICT.

PubMed

Milic, Natasa M; Ilic, Nikola; Stanisavljevic, Dejana M; Cirkovic, Andja M; Milin, Jelena S; Bukumiric, Zoran M; Milic, Nikola V; Savic, Marko D; Ristic, Sara M; Trajkovic, Goran Z

2018-01-01

Education is undergoing profound changes due to permanent technological innovations. This paper reports the results of a pilot study aimed at developing, implementing and evaluating the course, "Applicative Use of Information and Communication Technologies (ICT) in Medicine," upon medical school entry. The Faculty of Medicine, University of Belgrade, introduced a curriculum reform in 2014 that included the implementation of the course, "Applicative Use of ICT in Medicine" for first year medical students. The course was designed using a blended learning format to introduce the concepts of Web-based learning environments. Data regarding student knowledge, use and attitudes towards ICT were prospectively collected for the classes of 2015/16 and 2016/17. The teaching approach was supported by multimedia didactic materials using Moodle LMS. The overall quality of the course was also assessed. The five level Likert scale was used to measure attitudes related to ICT. In total, 1110 students were assessed upon medical school entry. A small number of students (19%) had previous experience with e-learning. Students were largely in agreement that informatics is needed in medical education, and that it is also useful for doctors (4.1±1.0 and 4.1±0.9, respectively). Ability in informatics and use of the Internet in education in the adjusted multivariate regression model were significantly associated with positive student attitudes toward ICT. More than 80% of students stated that they had learned to evaluate medical information and would use the Internet to search medical literature as an additional source for education. The majority of students (77%) agreed that a blended learning approach facilitates access to learning materials and enables time independent learning (72%). Implementing the blended learning course, "Applicative Use of ICT in Medicine," may bridge the gap between medicine and informatics upon medical school entry. Students displayed positive attitudes towards using ICT and gained adequate skills necessary to function effectively in an information-rich environment.

Bridging the gap between informatics and medicine upon medical school entry: Implementing a course on the Applicative Use of ICT

PubMed Central

Ilic, Nikola; Stanisavljevic, Dejana M.; Cirkovic, Andja M.; Milin, Jelena S.; Bukumiric, Zoran M.; Milic, Nikola V.; Savic, Marko D.; Ristic, Sara M.; Trajkovic, Goran Z.

2018-01-01

Education is undergoing profound changes due to permanent technological innovations. This paper reports the results of a pilot study aimed at developing, implementing and evaluating the course, "Applicative Use of Information and Communication Technologies (ICT) in Medicine," upon medical school entry. The Faculty of Medicine, University of Belgrade, introduced a curriculum reform in 2014 that included the implementation of the course, “Applicative Use of ICT in Medicine” for first year medical students. The course was designed using a blended learning format to introduce the concepts of Web-based learning environments. Data regarding student knowledge, use and attitudes towards ICT were prospectively collected for the classes of 2015/16 and 2016/17. The teaching approach was supported by multimedia didactic materials using Moodle LMS. The overall quality of the course was also assessed. The five level Likert scale was used to measure attitudes related to ICT. In total, 1110 students were assessed upon medical school entry. A small number of students (19%) had previous experience with e-learning. Students were largely in agreement that informatics is needed in medical education, and that it is also useful for doctors (4.1±1.0 and 4.1±0.9, respectively). Ability in informatics and use of the Internet in education in the adjusted multivariate regression model were significantly associated with positive student attitudes toward ICT. More than 80% of students stated that they had learned to evaluate medical information and would use the Internet to search medical literature as an additional source for education. The majority of students (77%) agreed that a blended learning approach facilitates access to learning materials and enables time independent learning (72%). Implementing the blended learning course, "Applicative Use of ICT in Medicine," may bridge the gap between medicine and informatics upon medical school entry. Students displayed positive attitudes towards using ICT and gained adequate skills necessary to function effectively in an information-rich environment. PMID:29684042

Data Validation Package June 2016 Groundwater and Surface Water Sampling at the Old and New Rifle, Colorado, Processing Sites September 2016

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bush, Richard; Lemke, Peter

Sampling Period: June 14–17 and July 7, 2016. Water samples were collected from 36 locations at New Rifle and Old Rifle, Colorado, Disposal/Processing Sites. Planned monitoring locations are shown in Attachment 1, Sampling and Analysis Work Order. Duplicate samples were collected from New Rifle locations 0216 and 0855, and Old Rifle location 0655. One equipment blank was collected after decontamination of non-dedicated equipment used to collect one surface water sample. See Attachment 2, Trip Report for additional details. Sampling and analyses were conducted as specified in the Sampling and Analysis Plan for U.S. Department of Energy Office of Legacy Managementmore » Sites (LMS/PRO/S04351, continually updated, http://energy.gov/lm/downloads/sampling-and- analysis-plan-us-department-energy-office-legacy-management-sites). New Rifle Site Samples were collected at the New Rifle site from 16 monitoring wells and 7 surface locations in compliance with the December 2008 Groundwater Compliance Action Plan [GCAP] for the New Rifle, Colorado, Processing Site (LMS/RFN/S01920). Monitoring well 0216 could not be sampled in June because it was surrounded by standing water due to the high river stage from spring runoff, it was later sampled in July. Monitoring well 0635 and surface location 0322 could not be sampled because access through the elk fence along Interstate 70 has not been completed at this time. Old Rifle Site Samples were collected at the Old Rifle site from eight monitoring wells and five surface locations in compliance with the December 2001 Ground Water Compliance Action Plan for the Old Rifle, Colorado, UMTRA Project Site (GJ0-2000-177-TAR).« less

78 FR 9056 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-07

... of automated collection techniques or other forms of information technology to minimize the... agent/brokers provided during training will be used to record their training history through CMS LMS...

Frequency-domain-independent vector analysis for mode-division multiplexed transmission

NASA Astrophysics Data System (ADS)

Liu, Yunhe; Hu, Guijun; Li, Jiao

2018-04-01

In this paper, we propose a demultiplexing method based on frequency-domain independent vector analysis (FD-IVA) algorithm for mode-division multiplexing (MDM) system. FD-IVA extends frequency-domain independent component analysis (FD-ICA) from unitary variable to multivariate variables, and provides an efficient method to eliminate the permutation ambiguity. In order to verify the performance of FD-IVA algorithm, a 6 ×6 MDM system is simulated. The simulation results show that the FD-IVA algorithm has basically the same bit-error-rate(BER) performance with the FD-ICA algorithm and frequency-domain least mean squares (FD-LMS) algorithm. Meanwhile, the convergence speed of FD-IVA algorithm is the same as that of FD-ICA. However, compared with the FD-ICA and the FD-LMS, the FD-IVA has an obviously lower computational complexity.

Performance analysis of structured gradient algorithm. [for adaptive beamforming linear arrays

NASA Technical Reports Server (NTRS)

Godara, Lal C.

1990-01-01

The structured gradient algorithm uses a structured estimate of the array correlation matrix (ACM) to estimate the gradient required for the constrained least-mean-square (LMS) algorithm. This structure reflects the structure of the exact array correlation matrix for an equispaced linear array and is obtained by spatial averaging of the elements of the noisy correlation matrix. In its standard form the LMS algorithm does not exploit the structure of the array correlation matrix. The gradient is estimated by multiplying the array output with the receiver outputs. An analysis of the two algorithms is presented to show that the covariance of the gradient estimated by the structured method is less sensitive to the look direction signal than that estimated by the standard method. The effect of the number of elements on the signal sensitivity of the two algorithms is studied.

Adaptive Control for Buck Power Converter Using Fixed Point Inducting Control and Zero Average Dynamics Strategies

NASA Astrophysics Data System (ADS)

Hoyos Velasco, Fredy Edimer; García, Nicolás Toro; Garcés Gómez, Yeison Alberto

In this paper, the output voltage of a buck power converter is controlled by means of a quasi-sliding scheme. The Fixed Point Inducting Control (FPIC) technique is used for the control design, based on the Zero Average Dynamics (ZAD) strategy, including load estimation by means of the Least Mean Squares (LMS) method. The control scheme is tested in a Rapid Control Prototyping (RCP) system based on Digital Signal Processing (DSP) for dSPACE platform. The closed loop system shows adequate performance. The experimental and simulation results match. The main contribution of this paper is to introduce the load estimator by means of LMS, to make ZAD and FPIC control feasible in load variation conditions. In addition, comparison results for controlled buck converter with SMC, PID and ZAD-FPIC control techniques are shown.

Close-form expression of one-tap normalized LMS carrier phase recovery in optical communication systems

NASA Astrophysics Data System (ADS)

Xu, Tianhua; Jacobsen, Gunnar; Popov, Sergei; Li, Jie; Liu, Tiegen; Zhang, Yimo

2016-10-01

The performance of long-haul high speed coherent optical fiber communication systems is significantly degraded by the laser phase noise and the equalization enhanced phase noise (EEPN). In this paper, the analysis of the one-tap normalized least-mean-square (LMS) carrier phase recovery (CPR) is carried out and the close-form expression is investigated for quadrature phase shift keying (QPSK) coherent optical fiber communication systems, in compensating both laser phase noise and equalization enhanced phase noise. Numerical simulations have also been implemented to verify the theoretical analysis. It is found that the one-tap normalized least-mean-square algorithm gives the same analytical expression for predicting CPR bit-error-rate (BER) floors as the traditional differential carrier phase recovery, when both the laser phase noise and the equalization enhanced phase noise are taken into account.