Sample records for local nonsimilarity method

  1. Unsteady boundary layer flow over a sphere in a porous medium

    NASA Astrophysics Data System (ADS)

    Mohammad, Nurul Farahain; Waini, Iskandar; Kasim, Abdul Rahman Mohd; Majid, Nurazleen Abdul

    2017-08-01

    This study focuses on the problem of unsteady boundary layer flow over a sphere in a porous medium. The governing equations which consists of a system of dimensional partial differential equations is applied with dimensionless parameter in order to attain non-dimensional partial differential equations. Later, the similarity transformation is performed in order to attain nonsimilar governing equations. Afterwards, the nonsimilar governing equations are solved numerically by using the Keller-Box method in Octave programme. The effect of porosity parameter is examined on separation time, velocity profile and skin friction of the unsteady flow. The results attained are presented in the form of table and graph.

  2. Boundary layer flow of air over water on a flat plate

    NASA Technical Reports Server (NTRS)

    Nelson, John; Alving, Amy E.; Joseph, Daniel D.

    1993-01-01

    A non-similar boundary layer theory for air blowing over a water layer on a flat plate is formulated and studied as a two-fluid problem in which the position of the interface is unknown. The problem is considered at large Reynolds number (based on x), away from the leading edge. A simple non-similar analytic solution of the problem is derived for which the interface height is proportional to x(sub 1/4) and the water and air flow satisfy the Blasius boundary layer equations, with a linear profile in the water and a Blasius profile in the air. Numerical studies of the initial value problem suggests that this asymptotic, non-similar air-water boundary layer solution is a global attractor for all initial conditions.

  3. Calculation methods for compressible turbulent boundary layers, 1976

    NASA Technical Reports Server (NTRS)

    Bushnell, D. M.; Cary, A. M., Jr.; Harris, J. E.

    1977-01-01

    Equations and closure methods for compressible turbulent boundary layers are discussed. Flow phenomena peculiar to calculation of these boundary layers were considered, along with calculations of three dimensional compressible turbulent boundary layers. Procedures for ascertaining nonsimilar two and three dimensional compressible turbulent boundary layers were appended, including finite difference, finite element, and mass-weighted residual methods.

  4. Optimal Threshold Determination for Interpreting Semantic Similarity and Particularity: Application to the Comparison of Gene Sets and Metabolic Pathways Using GO and ChEBI

    PubMed Central

    Bettembourg, Charles; Diot, Christian; Dameron, Olivier

    2015-01-01

    Background The analysis of gene annotations referencing back to Gene Ontology plays an important role in the interpretation of high-throughput experiments results. This analysis typically involves semantic similarity and particularity measures that quantify the importance of the Gene Ontology annotations. However, there is currently no sound method supporting the interpretation of the similarity and particularity values in order to determine whether two genes are similar or whether one gene has some significant particular function. Interpretation is frequently based either on an implicit threshold, or an arbitrary one (typically 0.5). Here we investigate a method for determining thresholds supporting the interpretation of the results of a semantic comparison. Results We propose a method for determining the optimal similarity threshold by minimizing the proportions of false-positive and false-negative similarity matches. We compared the distributions of the similarity values of pairs of similar genes and pairs of non-similar genes. These comparisons were performed separately for all three branches of the Gene Ontology. In all situations, we found overlap between the similar and the non-similar distributions, indicating that some similar genes had a similarity value lower than the similarity value of some non-similar genes. We then extend this method to the semantic particularity measure and to a similarity measure applied to the ChEBI ontology. Thresholds were evaluated over the whole HomoloGene database. For each group of homologous genes, we computed all the similarity and particularity values between pairs of genes. Finally, we focused on the PPAR multigene family to show that the similarity and particularity patterns obtained with our thresholds were better at discriminating orthologs and paralogs than those obtained using default thresholds. Conclusion We developed a method for determining optimal semantic similarity and particularity thresholds. We applied this method on the GO and ChEBI ontologies. Qualitative analysis using the thresholds on the PPAR multigene family yielded biologically-relevant patterns. PMID:26230274

  5. Mode localization in a class of multidegree-of-freedom nonlinear systems with cyclic symmetry

    NASA Astrophysics Data System (ADS)

    Vakakis, Alexander F.; Cetinkaya, Cetin

    1993-02-01

    The free oscillations of n-degree-of-freedom (DOF) nonlinear systems with cyclic symmetry and weak coupling between substructures are examined. An asymptotic methodology is used to detect localized nonsimilar normal modes, i.e., free periodic motions spatially confined to only a limited number of substructures of the cyclic system. It is shown that nonlinear mode localization occurs in the perfectly symmetric, weakly coupled structure, in contrast to linear mode localization, which exists only in the presence of substructure 'mistuning'. In addition to the localized modes, nonlocalized modes are also found in the weakly coupled system. The stability of the identified modes is investigated by means of an approximate two-timing averaging mothodology, and the general theory is applied to the case of a cyclic system with three-DOF. The theoretical results are then verified by direct numerical integrations of the equations of motion.

  6. The analysis of a nonsimilar laminar boundary layer

    NASA Technical Reports Server (NTRS)

    Stalmach, D. D.; Bertin, J. J.

    1978-01-01

    A computer code is described which yields accurate solutions for a broad range of laminar, nonsimilar boundary layers, providing the inviscid flow field is known. The boundary layer may be subject to mass injection for perfect-gas, nonreacting flows. If no mass injection is present, the code can be used with either perfect-gas or real-gas thermodynamic models. Solutions, ranging from two-dimensional similarity solutions to solutions for the boundary layer on the Space Shuttle Orbiter during reentry conditions, have been obtained with the code. Comparisons of these solutions, and others, with solutions presented in the literature; and with solutions obtained from other codes, demonstrate the accuracy of the present code.

  7. Laminar natural convection from a vertical plate with a step change in wall temperature

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, S.; Yovanovich, M.M.

    1991-05-01

    The study of natural convection heat transfer from a vertical flat plate in a quiescent medium has attracted a great deal of interest from many investigators in the past few decades. The plate with various thermal conditions that allow similarity transformations as well as those that are continuous and well defined have been examined. However, practical problems often involve wall conditions that are arbitrary and unknown a priori. To understand and solve problems involving general nonsimilar conditions at the wall, it is useful to investigate problems subjected to a step change in wall temperature. The problems impose a mathematical singularitymore » and severe nonsimilar conditions at the wall. In this paper, a new analytical model that can deal with a discontinuous wall temperature variation is presented. The method results in a set of approximate solutions for temperature and velocity distributions. The validity and accuracy of the model is demonstrated by comparisons with the results of the aforementioned investigators. The agreement is excellent and the results obtained with the solution of this work are remarkably close to existing numerical data of Hayday et al. and the perturbation series solution of Kao.« less

  8. Nonsimilar Solution for Shock Waves in a Rotational Axisymmetric Perfect Gas with a Magnetic Field and Exponentially Varying Density

    NASA Astrophysics Data System (ADS)

    Nath, G.; Sinha, A. K.

    2017-01-01

    The propagation of a cylindrical shock wave in an ideal gas in the presence of a constant azimuthal magnetic field with consideration for the axisymmetric rotational effects is investigated. The ambient medium is assumed to have the radial, axial, and azimuthal velocity components. The fluid velocities and density of the ambient medium are assumed to vary according to an exponential law. Nonsimilar solutions are obtained by taking into account the vorticity vector and its components. The dependences of the characteristics of the problem on the Alfven-Mach number and time are obtained. It is shown that the presence of a magnetic field has a decaying effect on the shock wave. The pressure and density are shown to vanish at the inner surface (piston), and hence a vacuum forms at the line of symmetry.

  9. Quadratic Convective Flow of a Micropolar Fluid along an Inclined Plate in a Non-Darcy Porous Medium with Convective Boundary Condition

    NASA Astrophysics Data System (ADS)

    RamReddy, Ch.; Naveen, P.; Srinivasacharya, D.

    2017-06-01

    The objective of the present study is to investigate the effect of nonlinear variation of density with temperature and concentration on the mixed convective flow of a micropolar fluid over an inclined flat plate in a non-Darcy porous medium in the presence of the convective boundary condition. In order to analyze all the essential features, the governing non-dimensional partial differential equations are transformed into a system of ordinary differential equations using a local non-similarity procedure and then the resulting boundary value problem is solved using a successive linearisation method (SLM). By insisting the comparison between vertical, horizontal and inclined plates, the physical quantities of the flow and its characteristics are exhibited graphically and quantitatively with various parameters. An increase in the micropolar parameter and non-Darcy parameter tend to increase the skin friction and the reverse change is observed in wall couple stress, mass and heat transfer rates. The influence of the nonlinear concentration parameter is more prominent on all the physical characteristics of the present model, compared with that of nonlinear temperature parameter.

  10. Short-Term Memory Coding in Children with Intellectual Disabilities

    ERIC Educational Resources Information Center

    Henry, Lucy

    2008-01-01

    To examine visual and verbal coding strategies, I asked children with intellectual disabilities and peers matched for MA and CA to perform picture memory span tasks with phonologically similar, visually similar, long, or nonsimilar named items. The CA group showed effects consistent with advanced verbal memory coding (phonological similarity and…

  11. Boundary-layer transition and displacement thickness effects on zero-lift drag of a series of power-law bodies at Mach 6

    NASA Technical Reports Server (NTRS)

    Ashby, G. C., Jr.; Harris, J. E.

    1974-01-01

    Wave and skin-friction drag have been numerically calculated for a series of power-law bodies at a Mach number of 6 and Reynolds numbers, based on body length, from 1.5 million to 9.5 million. Pressure distributions were computed on the nose by the inverse method and on the body by the method of characteristics. These pressure distributions and the measured locations of boundary-layer transition were used in a nonsimilar-boundary-layer program to determine viscous effects. A coupled iterative approach between the boundary-layer and pressure-distribution programs was used to account for boundary-layer displacement-thickness effects. The calculated-drag coefficients compared well with previously obtained experimental data.

  12. The stagnation-point flow towards a shrinking sheet with homogeneous - heterogeneous reactions effects: A stability analysis

    NASA Astrophysics Data System (ADS)

    Ismail, Nurul Syuhada; Arifin, Norihan Md.; Bachok, Norfifah; Mahiddin, Norhasimah

    2017-01-01

    A numerical study is performed to evaluate the problem of stagnation - point flow towards a shrinking sheet with homogeneous - heterogeneous reaction effects. By using non-similar transformation, the governing equations be able to reduced to an ordinary differential equation. Then, results of the equations can be obtained numerically by shooting method with maple implementation. Based on the numerical results obtained, the velocity ratio parameter λ< 0, the dual solutions do exist. Then, the stability analysis is carried out to determine which solution is more stable between both of the solutions by bvp4c solver in Matlab.

  13. Detecting Distortion: Bridging Visual and Quantitative Reasoning on Similarity Tasks

    ERIC Educational Resources Information Center

    Cox, Dana C.; Lo, Jane-Jane

    2014-01-01

    This study is focused on identifying and describing the reasoning patterns of middle grade students when examining potentially similar figures. Described here is a framework that includes 11 strategies that students used during clinical interview to differentiate similar and non-similar figures. Two factors were found to influence the strategies…

  14. A Theoretical Study of the Luminosity-Temperature Relation for Clusters of Galaxies

    NASA Astrophysics Data System (ADS)

    Del Popolo, A.; Hiotelis, N.; Peñarrubia, J.

    2005-07-01

    A luminosity-temperature relation is derived for clusters of galaxies. The two models used take into account the angular momentum acquisition by the protostructures during their expansion and collapse. The first model is a modification of the self-similar model, while the second is a modification of the punctuated equilibria model of Cavaliere et al. In both models the mass-temperature relation (M-T) used is based on previous calculations of Del Popolo. We show that the above models lead, in X-rays, to a luminosity-temperature relation that scales as L~T5 at the scale of groups, flattening to L~T3 for rich clusters and converging to L~T2 at higher temperatures. However, a fundamental result of our paper is that the nonsimilarity in the L-T relation can be explained by a simple model that takes into account the amount of angular momentum of a protostructure. This result is in disagreement with the widely accepted idea that the nonsimilarity is due to nongravitating processes, such as heating and/or cooling.

  15. Heat and mass transfer in combustion - Fundamental concepts and analytical techniques

    NASA Technical Reports Server (NTRS)

    Law, C. K.

    1984-01-01

    Fundamental combustion phenomena and the associated flame structures in laminar gaseous flows are discussed on physical bases within the framework of the three nondimensional parameters of interest to heat and mass transfer in chemically-reacting flows, namely the Damkoehler number, the Lewis number, and the Arrhenius number which is the ratio of the reaction activation energy to the characteristic thermal energy. The model problems selected for illustration are droplet combustion, boundary layer combustion, and the propagation, flammability, and stability of premixed flames. Fundamental concepts discussed include the flame structures for large activation energy reactions, S-curve interpretation of the ignition and extinctin states, reaction-induced local-similarity and non-similarity in boundary layer flows, the origin and removal of the cold boundary difficulty in modeling flame propagation, and effects of flame stretch and preferential diffusion on flame extinction and stability. Analytical techniques introduced include the Shvab-Zeldovich formulation, the local Shvab-Zeldovich formulation, flame-sheet approximation and the associated jump formulation, and large activation energy matched asymptotic analysis. Potentially promising research areas are suggested.

  16. Finite volume solution of the compressible boundary-layer equations

    NASA Technical Reports Server (NTRS)

    Loyd, B.; Murman, E. M.

    1986-01-01

    A box-type finite volume discretization is applied to the integral form of the compressible boundary layer equations. Boundary layer scaling is introduced through the grid construction: streamwise grid lines follow eta = y/h = const., where y is the normal coordinate and h(x) is a scale factor proportional to the boundary layer thickness. With this grid, similarity can be applied explicity to calculate initial conditions. The finite volume method preserves the physical transparency of the integral equations in the discrete approximation. The resulting scheme is accurate, efficient, and conceptually simple. Computations for similar and non-similar flows show excellent agreement with tabulated results, solutions computed with Keller's Box scheme, and experimental data.

  17. Finite-Difference Solution for Laminar or Turbulent Boundary Layer Flow over Axisymmetric Bodies with Ideal Gas, CF4, or Equilibrium Air Chemistry

    NASA Technical Reports Server (NTRS)

    Hamilton, H. Harris, II; Millman, Daniel R.; Greendyke, Robert B.

    1992-01-01

    A computer code was developed that uses an implicit finite-difference technique to solve nonsimilar, axisymmetric boundary layer equations for both laminar and turbulent flow. The code can treat ideal gases, air in chemical equilibrium, and carbon tetrafluoride (CF4), which is a useful gas for hypersonic blunt-body simulations. This is the only known boundary layer code that can treat CF4. Comparisons with experimental data have demonstrated that accurate solutions are obtained. The method should prove useful as an analysis tool for comparing calculations with wind tunnel experiments and for making calculations about flight vehicles where equilibrium air chemistry assumptions are valid.

  18. Finite-difference solution for laminar or turbulent boundary layer flow over axisymmetric bodies with ideal gas, CF4, or equilibrium air chemistry

    NASA Astrophysics Data System (ADS)

    Hamilton, H. Harris, II; Millman, Daniel R.; Greendyke, Robert B.

    1992-12-01

    A computer code was developed that uses an implicit finite-difference technique to solve nonsimilar, axisymmetric boundary layer equations for both laminar and turbulent flow. The code can treat ideal gases, air in chemical equilibrium, and carbon tetrafluoride (CF4), which is a useful gas for hypersonic blunt-body simulations. This is the only known boundary layer code that can treat CF4. Comparisons with experimental data have demonstrated that accurate solutions are obtained. The method should prove useful as an analysis tool for comparing calculations with wind tunnel experiments and for making calculations about flight vehicles where equilibrium air chemistry assumptions are valid.

  19. Detecting distortion: bridging visual and quantitative reasoning on similarity tasks

    NASA Astrophysics Data System (ADS)

    Cox, Dana C.; Lo, Jane-Jane

    2014-03-01

    This study is focused on identifying and describing the reasoning patterns of middle grade students when examining potentially similar figures. Described here is a framework that includes 11 strategies that students used during clinical interview to differentiate similar and non-similar figures. Two factors were found to influence the strategies students selected: the complexity of the figures being compared and the type of distortion present in nonsimilar pairings. Data from this study support the theory that distortions are identified as a dominant property of figures and that students use the presence and absence of distortion to visually decide if two figures are similar. Furthermore, this study shows that visual reasoning is not as primitive or nonconstructive as represented in earlier literature and supports students who are developing numeric reasoning strategies. This illuminates possible pathways students may take when advancing from using visual and additive reasoning strategies to using multiplicative proportional reasoning on similarity tasks. In particular, distortion detection is a visual activity that enables students to reflect upon and evaluate the validity and accuracy of differentiation and quantify perceived relationships leading to ratio. This study has implications for curriculum developers as well as future research.

  20. Identification of Transgenic Organisms Based on Terahertz Spectroscopy and Hyper Sausage Neuron

    NASA Astrophysics Data System (ADS)

    Liu, J.; Li, Zh.; Hu, F.; Chen, T.; Du, Y.; Xin, H.

    2015-03-01

    This paper presents a novel approach for identifi cation of terahertz (THz) spectra of genetically modifi ed organisms (GMOs) based on hyper sausage neuron (HSN), and THz transmittance spectra of some typical transgenic sugarbeet samples are investigated to demonstrate its feasibility. Principal component analysis (PCA) is applied to extract features of the spectrum data, and instead of the original spectrum data, the feature signals are fed into the HSN pattern recognition, a new multiple weights neural network (MWNN). The experimental result shows that the HSN model not only can correctly classify different types of transgenic sugar-beets, but also can reject nonsimilar samples of the same type. The proposed approach provides a new effective method for detection and identification of genetically modified organisms by using THz spectroscopy.

  1. Transpiration cooling of hypersonic blunt bodies with finite rate surface reactions

    NASA Technical Reports Server (NTRS)

    Henline, William D.

    1989-01-01

    The convective heat flux blockage to blunt body and hypersonic vehicles by transpiration cooling are presented. The general problem of mass addition to laminar boundary layers is reviewed. Results of similarity analysis of the boundary layer problem are provided for surface heat flux with transpiration cooling. Detailed non-similar results are presented from the numerical program, BLIMPK. Comparisons are made with the similarity theory. The effects of surface catalysis are investigated.

  2. Boundary Layer Flow of Air Over Water on a Flat Plate

    DTIC Science & Technology

    1993-08-01

    similar (or coupled self -similar) solution appears to be a global attractor for all initial conditions. 2 Governing Equations A water film of height y...assumptions are self -consistent. The reader may verify that the solution (13) with c(x) given by (16) is self -similar (satisfies (24) without the the...attractor for all solutions of this non-similar family. Self similar boundary layers depend only on q and not on 4. The ý derivatives of u, v and y* may

  3. Theoretical gain optimization studies in 10. 6. mu. m CO/sub 2/--N/sub 2/ gasdynamic lasers. IV. Further results of parametric study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Reddy, K.P.J.; Reddy, N.M.

    1984-01-01

    Based on a method proposed by Reddy and Shanmugasundaram, similar solutions have been obtained for the steady inviscid quasi-one-dimensional nonreacting flow in the supersonic nozzle of CO/sub 2/--N/sub 2/--H/sub 2/O and CO/sub 2/--N/sub 2/--He gasdynamic laser systems. Instead of using the correlations of a nonsimilar function N/sub S/ for pure N/sub 2/ gas, as is done in previous publications, the N/sub S/ correlations are computed here for the actual gas mixtures used in the gasdynamic lasers. Optimum small-signal optical gain and the corresponding optimum values of the operating parameters like reservoir pressure and temperature and nozzle area ratio are computedmore » using these correlations. The present results are compared with the previous results and the main differences are discussed.« less

  4. The effect of local/topical analgesics on incisional pain in a pig model.

    PubMed

    Castel, David; Sabbag, Itai; Meilin, Sigal

    2017-01-01

    Interest in the development of new topical/local drug administration for blocking pain at peripheral sites, with maximum drug activity and minimal systemic effects, is on the rise. In the review article by Kopsky and Stahl, four critical barriers in the process of research and development of topical analgesics were indicated. The active pharmaceutical ingredient (API) and the formulation are among the major challenges. The road to the development of such drugs passes through preclinical studies. These studies, if planned correctly, should serve as guidance for choosing the right API and formulation. Although rodent models for pain continue to provide valuable data on the mechanisms driving pain, their use in developing topical and localized treatment approaches is limited for technical (intraplate injection area is small) as well as mechanical reasons (non-similarity to human skin and innervation). It has been previously shown that pigs are comparable to humans in ways that make them a better choice for evaluating topical and local analgesics. The aim of this study was to summarize several experiments that used pigs for testing postoperative pain in an incisional pain model (skin incision [SI] and skin and muscle incision [SMI]). At the end of the surgery, the animals were treated with different doses of bupivacaine solution (Marcaine ® ), bupivacaine liposomal formulation (Exparel ® ) or ropivacaine solution (Naropin). Von Frey testing demonstrated a decrease in the animals' sensitivity to mechanical stimulation expressed as an increase in the withdrawal force following local treatment. These changes reflect the clinical condition in the level as well as in the duration of the response. These data indicate a good resemblance between pig and human skin and suggest that use of these animals in the preclinical phase of developing topical analgesics can, to some extent, release the bottleneck.

  5. Investigation of thermal protection systems effects on viscid and inviscid flow fields for manned entry systems

    NASA Technical Reports Server (NTRS)

    Bartlett, E. P.; Morse, H. L.; Tong, H.

    1971-01-01

    Procedures and methods for predicting aerothermodynamic heating to delta orbiter shuttle vehicles were reviewed. A number of approximate methods were found to be adequate for large scale parameter studies, but are considered inadequate for final design calculations. It is recommended that final design calculations be based on a computer code which accounts for nonequilibrium chemistry, streamline spreading, entropy swallowing, and turbulence. It is further recommended that this code be developed with the intent that it can be directly coupled with an exact inviscid flow field calculation when the latter becomes available. A nonsimilar, equilibrium chemistry computer code (BLIMP) was used to evaluate the effects of entropy swallowing, turbulence, and various three dimensional approximations. These solutions were compared with available wind tunnel data. It was found study that, for wind tunnel conditions, the effect of entropy swallowing and three dimensionality are small for laminar boundary layers but entropy swallowing causes a significant increase in turbulent heat transfer. However, it is noted that even small effects (say, 10-20%) may be important for the shuttle reusability concept.

  6. Characteristics of Coupled Nongray Radiating Gas Flows with Ablation Product Effects About Blunt Bodies During Planetary Entries. Ph.D. Thesis - North Carolina State Univ.

    NASA Technical Reports Server (NTRS)

    Sutton, K.

    1973-01-01

    A computational method was developed for the fully-coupled solution of nongray, radiating gas flows with ablation product effects about blunt bodies during planetary entries. The treatment of radiation accounts for molecular band, continuum, and atomic line transitions with a detailed frequency dependence of the absorption coefficient. The ablation of the entry body was solved as part of the solution for a steady-state ablation process. The method was applied by results at typical conditions during entry to Venus. The radiative heating rates along the downstream region of the body can exceed the stagnation point value. The radiative heating to the body is attenuated in the boundary layer at the downstream region of the body and at the stagnation point of the body. A study of the radiation, inviscid flow about spherically capped, conical bodies during planetary entries shows that the nondimensional, radiative heating distributions are nonsimilar with entry conditions. Caution should be exercised in attempting to extrapolate results from known distributions to other entry conditions for which solutions have not yet been obtained.

  7. Change Detection via Selective Guided Contrasting Filters

    NASA Astrophysics Data System (ADS)

    Vizilter, Y. V.; Rubis, A. Y.; Zheltov, S. Y.

    2017-05-01

    Change detection scheme based on guided contrasting was previously proposed. Guided contrasting filter takes two images (test and sample) as input and forms the output as filtered version of test image. Such filter preserves the similar details and smooths the non-similar details of test image with respect to sample image. Due to this the difference between test image and its filtered version (difference map) could be a basis for robust change detection. Guided contrasting is performed in two steps: at the first step some smoothing operator (SO) is applied for elimination of test image details; at the second step all matched details are restored with local contrast proportional to the value of some local similarity coefficient (LSC). The guided contrasting filter was proposed based on local average smoothing as SO and local linear correlation as LSC. In this paper we propose and implement new set of selective guided contrasting filters based on different combinations of various SO and thresholded LSC. Linear average and Gaussian smoothing, nonlinear median filtering, morphological opening and closing are considered as SO. Local linear correlation coefficient, morphological correlation coefficient (MCC), mutual information, mean square MCC and geometrical correlation coefficients are applied as LSC. Thresholding of LSC allows operating with non-normalized LSC and enhancing the selective properties of guided contrasting filters: details are either totally recovered or not recovered at all after the smoothing. These different guided contrasting filters are tested as a part of previously proposed change detection pipeline, which contains following stages: guided contrasting filtering on image pyramid, calculation of difference map, binarization, extraction of change proposals and testing change proposals using local MCC. Experiments on real and simulated image bases demonstrate the applicability of all proposed selective guided contrasting filters. All implemented filters provide the robustness relative to weak geometrical discrepancy of compared images. Selective guided contrasting based on morphological opening/closing and thresholded morphological correlation demonstrates the best change detection result.

  8. Comparison of CME/Shock Propagation Models with Heliospheric Imaging and In Situ Observations

    NASA Astrophysics Data System (ADS)

    Zhao, Xinhua; Liu, Ying D.; Inhester, Bernd; Feng, Xueshang; Wiegelmann, Thomas; Lu, Lei

    2016-10-01

    The prediction of the arrival time for fast coronal mass ejections (CMEs) and their associated shocks is highly desirable in space weather studies. In this paper, we use two shock propagation models, I.e., Data Guided Shock Time Of Arrival (DGSTOA) and Data Guided Shock Propagation Model (DGSPM), to predict the kinematical evolution of interplanetary shocks associated with fast CMEs. DGSTOA is based on the similarity theory of shock waves in the solar wind reference frame, and DGSPM is based on the non-similarity theory in the stationary reference frame. The inputs are the kinematics of the CME front at the maximum speed moment obtained from the geometric triangulation method applied to STEREO imaging observations together with the Harmonic Mean approximation. The outputs provide the subsequent propagation of the associated shock. We apply these models to the CMEs on 2012 January 19, January 23, and March 7. We find that the shock models predict reasonably well the shock’s propagation after the impulsive acceleration. The shock’s arrival time and local propagation speed at Earth predicted by these models are consistent with in situ measurements of WIND. We also employ the Drag-Based Model (DBM) as a comparison, and find that it predicts a steeper deceleration than the shock models after the rapid deceleration phase. The predictions of DBM at 1 au agree with the following ICME or sheath structure, not the preceding shock. These results demonstrate the applicability of the shock models used here for future arrival time prediction of interplanetary shocks associated with fast CMEs.

  9. Numerical studies of transverse curvature effects on transonic flow stability

    NASA Technical Reports Server (NTRS)

    Macaraeg, M. G.; Daudpota, Q. I.

    1992-01-01

    A numerical study of transverse curvature effects on compressible flow temporal stability for transonic to low supersonic Mach numbers is presented for axisymmetric modes. The mean flows studied include a similar boundary-layer profile and a nonsimilar axisymmetric boundary-layer solution. The effect of neglecting curvature in the mean flow produces only small quantitative changes in the disturbance growth rate. For transonic Mach numbers (1-1.4) and aerodynamically relevant Reynolds numbers (5000-10,000 based on displacement thickness), the maximum growth rate is found to increase with curvature - the maximum occurring at a nondimensional radius (based on displacement thickness) between 30 and 100.

  10. Computational analysis of non-Newtonian boundary layer flow of nanofluid past a semi-infinite vertical plate with partial slip

    NASA Astrophysics Data System (ADS)

    Amanulla, C. H.; Nagendra, N.; Suryanarayana Reddy, M.

    2018-03-01

    An analysis of this paper is examined, two-dimensional, laminar with heat and mass transfer of natural convective nanofluid flow past a semi-infinite vertical plate surface with velocity and thermal slip effects are studied theoretically. The coupled governing partial differential equations are transformed to ordinary differential equations by using non-similarity transformations. The obtained ordinary differential equations are solved numerically by a well-known method named as Keller Box Method (KBM). The influences of the emerging parameters i.e. Casson fluid parameter (β), Brownian motion parameter (Nb), thermophoresis parameter (Nt), Buoyancy ratio parameter (N), Lewis number (Le), Prandtl number (Pr), Velocity slip factor (Sf) and Thermal slip factor (ST) on velocity, temperature and nano-particle concentration distributions is illustrated graphically and interpreted at length. The major sources of nanoparticle migration in Nanofluids are Thermophoresis and Brownian motion. A suitable agreement with existing published literature is made and an excellent agreement is observed for the limiting case and also validation of solutions with a Nakamura tridiagonal method has been included. It is observed that nanoparticle concentrations on surface decreases with an increase in slip parameter. The study is relevant to enrobing processes for electric-conductive nano-materials, of potential use in aerospace and other industries.

  11. Short-term memory coding in children with intellectual disabilities.

    PubMed

    Henry, Lucy

    2008-05-01

    To examine visual and verbal coding strategies, I asked children with intellectual disabilities and peers matched for MA and CA to perform picture memory span tasks with phonologically similar, visually similar, long, or nonsimilar named items. The CA group showed effects consistent with advanced verbal memory coding (phonological similarity and word length effects). Neither the intellectual disabilities nor MA groups showed evidence for memory coding strategies. However, children in these groups with MAs above 6 years showed significant visual similarity and word length effects, broadly consistent with an intermediate stage of dual visual and verbal coding. These results suggest that developmental progressions in memory coding strategies are independent of intellectual disabilities status and consistent with MA.

  12. On the wall-normal velocity of the compressible boundary-layer equations

    NASA Technical Reports Server (NTRS)

    Pruett, C. David

    1991-01-01

    Numerical methods for the compressible boundary-layer equations are facilitated by transformation from the physical (x,y) plane to a computational (xi,eta) plane in which the evolution of the flow is 'slow' in the time-like xi direction. The commonly used Levy-Lees transformation results in a computationally well-behaved problem for a wide class of non-similar boundary-layer flows, but it complicates interpretation of the solution in physical space. Specifically, the transformation is inherently nonlinear, and the physical wall-normal velocity is transformed out of the problem and is not readily recovered. In light of recent research which shows mean-flow non-parallelism to significantly influence the stability of high-speed compressible flows, the contribution of the wall-normal velocity in the analysis of stability should not be routinely neglected. Conventional methods extract the wall-normal velocity in physical space from the continuity equation, using finite-difference techniques and interpolation procedures. The present spectrally-accurate method extracts the wall-normal velocity directly from the transformation itself, without interpolation, leaving the continuity equation free as a check on the quality of the solution. The present method for recovering wall-normal velocity, when used in conjunction with a highly-accurate spectral collocation method for solving the compressible boundary-layer equations, results in a discrete solution which is extraordinarily smooth and accurate, and which satisfies the continuity equation nearly to machine precision. These qualities make the method well suited to the computation of the non-parallel mean flows needed by spatial direct numerical simulations (DNS) and parabolized stability equation (PSE) approaches to the analysis of stability.

  13. G-Jitter Induced Magnetohydrodynamics Flow of Nanofluid with Constant Convective Thermal and Solutal Boundary Conditions

    PubMed Central

    Uddin, Mohammed J.; Khan, Waqar A.; Ismail, Ahmad Izani Md.

    2015-01-01

    Taking into account the effect of constant convective thermal and mass boundary conditions, we present numerical solution of the 2-D laminar g-jitter mixed convective boundary layer flow of water-based nanofluids. The governing transport equations are converted into non-similar equations using suitable transformations, before being solved numerically by an implicit finite difference method with quasi-linearization technique. The skin friction decreases with time, buoyancy ratio, and thermophoresis parameters while it increases with frequency, mixed convection and Brownian motion parameters. Heat transfer rate decreases with time, Brownian motion, thermophoresis and diffusion-convection parameters while it increases with the Reynolds number, frequency, mixed convection, buoyancy ratio and conduction-convection parameters. Mass transfer rate decreases with time, frequency, thermophoresis, conduction-convection parameters while it increases with mixed convection, buoyancy ratio, diffusion-convection and Brownian motion parameters. To the best of our knowledge, this is the first paper on this topic and hence the results are new. We believe that the results will be useful in designing and operating thermal fluids systems for space materials processing. Special cases of the results have been compared with published results and an excellent agreement is found. PMID:25933066

  14. An Automated Procedure for Evaluating Song Imitation

    PubMed Central

    Mandelblat-Cerf, Yael; Fee, Michale S.

    2014-01-01

    Songbirds have emerged as an excellent model system to understand the neural basis of vocal and motor learning. Like humans, songbirds learn to imitate the vocalizations of their parents or other conspecific “tutors.” Young songbirds learn by comparing their own vocalizations to the memory of their tutor song, slowly improving until over the course of several weeks they can achieve an excellent imitation of the tutor. Because of the slow progression of vocal learning, and the large amounts of singing generated, automated algorithms for quantifying vocal imitation have become increasingly important for studying the mechanisms underlying this process. However, methodologies for quantifying song imitation are complicated by the highly variable songs of either juvenile birds or those that learn poorly because of experimental manipulations. Here we present a method for the evaluation of song imitation that incorporates two innovations: First, an automated procedure for selecting pupil song segments, and, second, a new algorithm, implemented in Matlab, for computing both song acoustic and sequence similarity. We tested our procedure using zebra finch song and determined a set of acoustic features for which the algorithm optimally differentiates between similar and non-similar songs. PMID:24809510

  15. A rational approach to the use of Prandtl's mixing length model in free turbulent shear flow calculations

    NASA Technical Reports Server (NTRS)

    Rudy, D. H.; Bushnell, D. M.

    1973-01-01

    Prandtl's basic mixing length model was used to compute 22 test cases on free turbulent shear flows. The calculations employed appropriate algebraic length scale equations and single values of mixing length constant for planar and axisymmetric flows, respectively. Good agreement with data was obtained except for flows, such as supersonic free shear layers, where large sustained sensitivity changes occur. The inability to predict the more gradual mixing in these flows is tentatively ascribed to the presence of a significant turbulence-induced transverse static pressure gradient which is neglected in conventional solution procedures. Some type of an equation for length scale development was found to be necessary for successful computation of highly nonsimilar flow regions such as jet or wake development from thick wall flows.

  16. Hybrid antenna arrays with non-uniform Electromagnetic Band Gap lattices for wireless communication networks

    NASA Astrophysics Data System (ADS)

    Mourtzios, Ch.; Siakavara, K.

    2015-08-01

    A method to design hybrid antenna configurations with very low profile, suitable for smart and Multiple Input-Multiple Output antenna systems is proposed. The antennas are incorporated with novel Electromagnetic Band Gap (EBG) surfaces with non-similar cells. These non-uniform EBG surfaces have been properly designed to cause focusing, of the incident waves, thus enhancing the characteristics of operation of antenna elements positioned in close proximity to the surface and also to increase the isolation between them. Theoretical analysis of the reflection mechanism of this type of lattices as well as the prediction of the resulting performance of the antenna is presented. All these considerations are validated with implementation and simulation of the hybrid structures inside the Universal Mobile Telecommunications System frequency band. The results show that increment of the gain and isolation between the antenna elements can be obtained. Moreover, results for the correlation coefficient between the elements, for Gaussian distribution of the incoming waves have been received and the tolerance of the antennas to the variation of the polarization characteristics of the incoming waves has been investigated. A Genetic Algorithm has been constructed and applied to find the proper geometry of the hybrid antennas in order the correlation coefficient to be minimized and get almost independent from the polarization of incident waves.

  17. Multi-band reflector antenna with double-ring element frequency selective subreflector

    NASA Technical Reports Server (NTRS)

    Wu, Te-Kao; Lee, S. W.

    1993-01-01

    Frequency selective subreflectors (FSS) are often employed in the reflector antenna system of a communication satellite or a deep space exploration vehicle for multi-frequency operations. In the past, FSS's have been designed for diplexing two frequency bands. For example, the Voyager FSS was designed to diplex S and X bands and the TDRSS FSS was designed to diplex S and Ku bands. Recently, NASA's CASSINI project requires an FSS to multiplex four frequency (S/X/Ku/Ka) bands. Theoretical analysis and experimental verifications are presented for a multi-band flat pannel FSS with double-ring elements. Both the exact formulation and the thin-ring approximation are described for analyzing and designing this multi-ring patch element FSS. It is found that the thin-ring approximation fails to predict the electrically wide ring element FSS's performance. A single screen double-ring element FSS is demonstrated for the tri-band system that reflects the X-band signal while transmitting through the S- and Ku-band signals. In addition, a double screen FSS with non-similar double-ring elements is presented for the Cassini's four-band system which reflects the X- and Ka-band signals while passing the S- and Ku-band signals. To accurately predict the FSS effects on a dual reflector antenna's radiation pattern, the FSS subreflector's transmitted/reflected field variation as functions of the polarization and incident angles with respect to the local coordinates was taken into account. An FSS transmission/reflection coefficient table is computed for TE and TM polarizations at various incident angles based on the planar FSS model. Next, the hybrid Geometric Optics (GO) and Physical Optics (PO) technique is implemented with linearly interpolating the FSS table to efficiently determine the FSS effects in a dual reflector antenna.

  18. Structural analysis of B-cell epitopes in antibody:protein complexes

    PubMed Central

    Kringelum, Jens Vindahl; Nielsen, Morten; Padkjær, Søren Berg; Lund, Ole

    2012-01-01

    The binding of antigens to antibodies is one of the key events in an immune response against foreign molecules and is a critical element of several biomedical applications including vaccines and immunotherapeutics. For development of such applications, the identification of antibody binding sites (B-cell epitopes) is essential. However experimental epitope mapping is highly cost-intensive and computer-aided methods do in general have moderate performance. One major reason for this moderate performance is an incomplete understanding of what characterizes an epitope. To fill this gap, we here developed a novel framework for comparing and superimposing B-cell epitopes and applied it on a dataset of 107 non-similar antigen:antibody structures extracted from the PDB database. With the presented framework, we were able to describe the general B-cell epitope as a flat, oblong, oval shaped volume consisting of predominantly hydrophobic amino acids in the center flanked by charged residues. The average epitope was found to be made up of ~15 residues with one linear stretch of 5 or more residues constituting more than half of the epitope size. Furthermore, the epitope area is predominantly constrained to a plane above the antibody tip, in which the epitope is orientated in a −30 to 60 degree angle relative to the light to heavy chain antibody direction. Contrary to previously findings, we did not find a significant deviation between the amino acid composition in epitopes and the composition of equally exposed parts of the antigen surface. Our results, in combination with previously findings, give a detailed picture of the B-cell epitope that may be used in development of improved B-cell prediction methods. PMID:22784991

  19. g-Jitter Mixed Convective Slip Flow of Nanofluid past a Permeable Stretching Sheet Embedded in a Darcian Porous Media with Variable Viscosity

    PubMed Central

    Uddin, Mohammed J.; Khan, Waqar A.; Amin, Norsarahaida S.

    2014-01-01

    The unsteady two-dimensional laminar g-Jitter mixed convective boundary layer flow of Cu-water and Al2O3-water nanofluids past a permeable stretching sheet in a Darcian porous is studied by using an implicit finite difference numerical method with quasi-linearization technique. It is assumed that the plate is subjected to velocity and thermal slip boundary conditions. We have considered temperature dependent viscosity. The governing boundary layer equations are converted into non-similar equations using suitable transformations, before being solved numerically. The transport equations have been shown to be controlled by a number of parameters including viscosity parameter, Darcy number, nanoparticle volume fraction, Prandtl number, velocity slip, thermal slip, suction/injection and mixed convection parameters. The dimensionless velocity and temperature profiles as well as friction factor and heat transfer rates are presented graphically and discussed. It is found that the velocity reduces with velocity slip parameter for both nanofluids for fluid with both constant and variable properties. It is further found that the skin friction decreases with both Darcy number and momentum slip parameter while it increases with viscosity variation parameter. The surface temperature increases as the dimensionless time increases for both nanofluids. Nusselt numbers increase with mixed convection parameter and Darcy numbers and decreases with the momentum slip. Excellent agreement is found between the numerical results of the present paper with published results. PMID:24927277

  20. [Influence of different types of surface on the diversity of soil fauna in Beijing Olympic Park].

    PubMed

    Song, Ying-shi; Li, Xiao-wen; Li, Feng; Li, Hai-mei

    2015-04-01

    Soil fauna are impacted by urbanization. In order to explore the stress of different surface covers on diversity and community structure of soil fauna, we conducted this experiment in Beijing Olympic Park. In autumn of 2013, we used Baermann and Tullgren methods to study the diversity of soil fauna in the depth of 0-5 cm, 5-10 cm, 10-15 cm under four different land covers i.e. bared field (BF), totally impervious surface (TIS), partly impervious surface (PIS) and grassland (GL). The results showed that the total number of soil fauna in 100 cm3 was in order of GL (210) > PIS (193) > TIS (183) > BF (90), and the number of nematodes accounted for 72.0%-92.8% of the total number. On the vertical level, except for the TIS, the other three types of surface soil fauna had the surface gathered phenomenon. The Shannon diversity index and the Pielou evenness index of BF were lower, but the Simpson dominance index was higher than in the other land covers. The Shannon index and Margalef richness indes of GL were higher than those of the other land covers. The Shannon indexes of TIS and PIS were between the BF and GL. Except for the TIS and GL, the similarity indexes were between 0.4-0.5, indicating moderate non-similar characteristics. The diversity of soil fauna was significantly correlated with temperature, pH and available potassium.

  1. Global stability analysis of axisymmetric boundary layer over a circular cylinder

    NASA Astrophysics Data System (ADS)

    Bhoraniya, Ramesh; Vinod, Narayanan

    2018-05-01

    This paper presents a linear global stability analysis of the incompressible axisymmetric boundary layer on a circular cylinder. The base flow is parallel to the axis of the cylinder at inflow boundary. The pressure gradient is zero in the streamwise direction. The base flow velocity profile is fully non-parallel and non-similar in nature. The boundary layer grows continuously in the spatial directions. Linearized Navier-Stokes (LNS) equations are derived for the disturbance flow quantities in the cylindrical polar coordinates. The LNS equations along with homogeneous boundary conditions forms a generalized eigenvalues problem. Since the base flow is axisymmetric, the disturbances are periodic in azimuthal direction. Chebyshev spectral collocation method and Arnoldi's iterative algorithm is used for the solution of the general eigenvalues problem. The global temporal modes are computed for the range of Reynolds numbers and different azimuthal wave numbers. The largest imaginary part of the computed eigenmodes is negative, and hence, the flow is temporally stable. The spatial structure of the eigenmodes shows that the disturbance amplitudes grow in size and magnitude while they are moving towards downstream. The global modes of axisymmetric boundary layer are more stable than that of 2D flat-plate boundary layer at low Reynolds number. However, at higher Reynolds number they approach 2D flat-plate boundary layer. Thus, the damping effect of transverse curvature is significant at low Reynolds number. The wave-like nature of the disturbance amplitudes is found in the streamwise direction for the least stable eigenmodes.

  2. Tree edit distance for leaf-labelled trees on free leafset and its comparison with frequent subsplit dissimilarity and popular distance measures

    PubMed Central

    2011-01-01

    Background This paper is devoted to distance measures for leaf-labelled trees on free leafset. A leaf-labelled tree is a data structure which is a special type of a tree where only leaves (terminal) nodes are labelled. This data structure is used in bioinformatics for modelling of evolution history of genes and species and also in linguistics for modelling of languages evolution history. Many domain specific problems occur and need to be solved with help of tree postprocessing techniques such as distance measures. Results Here we introduce the tree edit distance designed for leaf labelled trees on free leafset, which occurs to be a metric. It is presented together with tree edit consensus tree notion. We provide statistical evaluation of provided measure with respect to R-F, MAST and frequent subsplit based dissimilarity measures as the reference measures. Conclusions The tree edit distance was proven to be a metric and has the advantage of using different costs for contraction and pruning, therefore their properties can be tuned depending on the needs of the user. Two of the presented methods carry the most interesting properties. E(3,1) is very discriminative (having a wide range of values) and has a very regular distance distribution which is similar to a normal distribution in its shape and is good both for similar and non-similar trees. NFC(2,1) on the other hand is proportional or nearly proportional to the number of mutation operations used, irrespective of their type. PMID:21612645

  3. Refractive index dependence of Papilio Ulysses butterfly wings reflectance spectra

    NASA Astrophysics Data System (ADS)

    Isnaeni, Muslimin, Ahmad Novi; Birowosuto, Muhammad Danang

    2016-02-01

    We have observed and utilized butterfly wings of Papilio Ulysses for refractive index sensor. We noticed this butterfly wings have photonic crystal structure, which causes blue color appearance on the wings. The photonic crystal structure, which consists of cuticle and air void, is approximated as one dimensional photonic crystal structure. This photonic crystal structure opens potential to several optical devices application, such as refractive index sensor. We have utilized small piece of Papilio Ulysses butterfly wings to characterize refractive index of several liquid base on reflectance spectrum of butterfly wings in the presence of sample liquid. For comparison, we simulated reflectance spectrum of one dimensional photonic crystal structure having material parameter based on real structure of butterfly wings. We found that reflectance spectrum peaks shifted as refractive index of sample changes. Although there is a slight difference in reflectance spectrum peaks between measured spectrum and calculated spectrum, the trend of reflectance spectrum peaks as function of sample's refractive index is the similar. We assume that during the measurement, the air void that filled by sample liquid is expanded due to liquid pressure. This change of void shape causes non-similarity between measured spectrum and calculated spectrum.

  4. Fast structure similarity searches among protein models: efficient clustering of protein fragments

    PubMed Central

    2012-01-01

    Background For many predictive applications a large number of models is generated and later clustered in subsets based on structure similarity. In most clustering algorithms an all-vs-all root mean square deviation (RMSD) comparison is performed. Most of the time is typically spent on comparison of non-similar structures. For sets with more than, say, 10,000 models this procedure is very time-consuming and alternative faster algorithms, restricting comparisons only to most similar structures would be useful. Results We exploit the inverse triangle inequality on the RMSD between two structures given the RMSDs with a third structure. The lower bound on RMSD may be used, when restricting the search of similarity to a reasonably low RMSD threshold value, to speed up similarity searches significantly. Tests are performed on large sets of decoys which are widely used as test cases for predictive methods, with a speed-up of up to 100 times with respect to all-vs-all comparison depending on the set and parameters used. Sample applications are shown. Conclusions The algorithm presented here allows fast comparison of large data sets of structures with limited memory requirements. As an example of application we present clustering of more than 100000 fragments of length 5 from the top500H dataset into few hundred representative fragments. A more realistic scenario is provided by the search of similarity within the very large decoy sets used for the tests. Other applications regard filtering nearly-indentical conformation in selected CASP9 datasets and clustering molecular dynamics snapshots. Availability A linux executable and a Perl script with examples are given in the supplementary material (Additional file 1). The source code is available upon request from the authors. PMID:22642815

  5. Towards a category theory approach to analogy: Analyzing re-representation and acquisition of numerical knowledge.

    PubMed

    Navarrete, Jairo A; Dartnell, Pablo

    2017-08-01

    Category Theory, a branch of mathematics, has shown promise as a modeling framework for higher-level cognition. We introduce an algebraic model for analogy that uses the language of category theory to explore analogy-related cognitive phenomena. To illustrate the potential of this approach, we use this model to explore three objects of study in cognitive literature. First, (a) we use commutative diagrams to analyze an effect of playing particular educational board games on the learning of numbers. Second, (b) we employ a notion called coequalizer as a formal model of re-representation that explains a property of computational models of analogy called "flexibility" whereby non-similar representational elements are considered matches and placed in structural correspondence. Finally, (c) we build a formal learning model which shows that re-representation, language processing and analogy making can explain the acquisition of knowledge of rational numbers. These objects of study provide a picture of acquisition of numerical knowledge that is compatible with empirical evidence and offers insights on possible connections between notions such as relational knowledge, analogy, learning, conceptual knowledge, re-representation and procedural knowledge. This suggests that the approach presented here facilitates mathematical modeling of cognition and provides novel ways to think about analogy-related cognitive phenomena.

  6. Towards a category theory approach to analogy: Analyzing re-representation and acquisition of numerical knowledge

    PubMed Central

    2017-01-01

    Category Theory, a branch of mathematics, has shown promise as a modeling framework for higher-level cognition. We introduce an algebraic model for analogy that uses the language of category theory to explore analogy-related cognitive phenomena. To illustrate the potential of this approach, we use this model to explore three objects of study in cognitive literature. First, (a) we use commutative diagrams to analyze an effect of playing particular educational board games on the learning of numbers. Second, (b) we employ a notion called coequalizer as a formal model of re-representation that explains a property of computational models of analogy called “flexibility” whereby non-similar representational elements are considered matches and placed in structural correspondence. Finally, (c) we build a formal learning model which shows that re-representation, language processing and analogy making can explain the acquisition of knowledge of rational numbers. These objects of study provide a picture of acquisition of numerical knowledge that is compatible with empirical evidence and offers insights on possible connections between notions such as relational knowledge, analogy, learning, conceptual knowledge, re-representation and procedural knowledge. This suggests that the approach presented here facilitates mathematical modeling of cognition and provides novel ways to think about analogy-related cognitive phenomena. PMID:28841643

  7. Advanced qualification of pharmaceutical excipient suppliers by multiple analytics and multivariate analysis combined.

    PubMed

    Hertrampf, A; Müller, H; Menezes, J C; Herdling, T

    2015-11-10

    Pharmaceutical excipients have different functions within a drug formulation, consequently they can influence the manufacturability and/or performance of medicinal products. Therefore, critical to quality attributes should be kept constant. Sometimes it may be necessary to qualify a second supplier, but its product will not be completely equal to the first supplier product. To minimize risks of not detecting small non-similarities between suppliers and to detect lot-to-lot variability for each supplier, multivariate data analysis (MVA) can be used as a more powerful alternative to classical quality control that uses one-parameter-at-a-time monitoring. Such approach is capable of supporting the requirements of a new guideline by the European Parliament and Council (2015/C-95/02) demanding appropriate quality control strategies for excipients based on their criticality and supplier risks in ensuring quality, safety and function. This study compares calcium hydrogen phosphate from two suppliers. It can be assumed that both suppliers use different manufacturing processes. Therefore, possible chemical and physical differences were investigated by using Raman spectroscopy, laser diffraction and X-ray powder diffraction. Afterwards MVA was used to extract relevant information from each analytical technique. Both CaHPO4 could be discriminated by their supplier. The gained knowledge allowed to specify an enhanced strategy for second supplier qualification. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. Specificity of Balance Training in Healthy Individuals: A Systematic Review and Meta-Analysis.

    PubMed

    Kümmel, Jakob; Kramer, Andreas; Giboin, Louis-Solal; Gruber, Markus

    2016-09-01

    It has become common practice to incorporate balance tasks into the training program for athletes who want to improve performance and prevent injuries, in rehabilitation programs, and in fall prevention programs for the elderly. However, it is still unclear whether incorporating balance tasks into a training program increases performance only in these specific tasks or if it affects balance in a more general way. The objective of this systematic literature review and meta-analysis was to determine to what extent the training of balance tasks can improve performance in non-trained balance tasks. A systematic literature search was performed in the online databases EMBASE, PubMed, SPORTDiscus and Web of Science. Articles related to balance training and testing in healthy populations published between January 1985 and March 2015 were considered. A total of 3093 articles were systematically evaluated. Randomized controlled trials were included that (i) used only balance tasks during the training, (ii) used at least two balance tests before and after training, and (iii) tested performance in the trained balance tasks and at least one non-trained balance task. Six studies with a total of 102 subjects met these criteria and were included into the meta-analysis. The quality of the studies was evaluated by means of the Physiotherapy Evidence Database (PEDro) scale. A random effect model was used to calculate the between-subject standardized mean differences (SMDbs) in order to quantify the effect of balance training on various kinds of balance measures relative to controls. The tested balance tasks in each study were classified into tasks that had been trained and tasks that had not been trained. For further analyses, the non-trained balance tasks were subdivided into tasks with similar or non-similar body position and similar or non-similar balance perturbation direction compared to the trained task. The effect of balance training on the performance of the trained balance tasks reached an SMDbs of 0.79 [95 % confidence interval (CI) 0.48-1.10], indicating a high effect in favor for the trained task, with no notable heterogeneity (I (2) = 0 %). The SMDbs in non-trained categories reached values between -0.07 (95 % CI -0.53 to 0.38) and 0.18 (95 % CI -0.27 to 0.64), with non-notable to moderate heterogeneity (I (2) = 0-32 %), indicating no effect of the balance training on the respective non-trained balance tasks. With six studies, the number of studies included in this meta-analysis is rather low. It remains unclear how the limited number of studies with considerable methodological diversity affects the outcome of the SMD calculations and thus the general outcome of the meta-analysis. In healthy populations, balance training can improve the performance in trained tasks, but may have only minor or no effects on non-trained tasks. Consequently, therapists and coaches should identify exactly those tasks that need improvement, and use these tasks in the training program and as a part of the test battery that evaluates the efficacy of the training program. Generic balance tasks-such as one-leg stance-may have little value as overall balance measures or when assessing the efficacy of specific training interventions.

  9. Moist Baroclinic Life Cycles in an Idealized Model with Varying Hydrostasy

    NASA Astrophysics Data System (ADS)

    Hsieh, T. L.; Garner, S.; Held, I.

    2016-12-01

    Baroclinic life cycles are simulated in a limited-area model having varying degrees of hydrostasy to examine their interaction with explicitly resolved moist convection. The life cycles are driven by an idealized sea surface temperature field in an f-plane channel, and no convective parameterization is used. The hydrostasy is controlled by rescaling the model equations following the hypohydrostatic rescaling and by changing the resolution. In experiments having the same ratio between the grid spacing and the rescaling factor, the simulated convection is shown to have the same hydrostasy, suggesting that the low resolution models have been rescaled to be as nonhydrostatic as the high resolution model without additional computational cost. The nonhydrostatic convective cells in the rescaled models are found to be wider and slower than those in the unscaled models, consistent with predictions of the similarity theory. For the same resolution, although the wider cells in the rescaled models have better resolved structure, the total latent heating is insensitive to the rescaling factor. This is because latent heating is constrained by long-wave cooling which is found to be insensitive to the model hydrostasy, requiring a non-similarity in the frequency and distribution of convection. Consequently, the resolved nonhydrostatic convection maintains the same stability profile as the unresolved hydrostatic convection, so the statistics of the life cycles are also insensitive to the rescaling factor. The findings suggest that the mean climate and internal variability would be unaffected by the hypohydrostatic rescaling when the self-organization of convection is not important.

  10. Prediction and forecast of Suspended Sediment Concentration (SSC) on the Upper Yangtze basin

    NASA Astrophysics Data System (ADS)

    Matos, José Pedro; Hassan, Marwan; Lu, Xixi; Franca, Mário J.

    2017-04-01

    Sediment transport in suspension may represent 90% or more of the global annual flux of sediment. For instance, more than 99% of the sediment supplied to the sea by the Yangtze River is suspended load. Suspended load is an important component for understanding channel dynamics and landscape evolution. Sediments transported in suspension are a major source of nutrients for aquatic organisms in riparian and floodplain habitats, and play a beneficial role acting as a sink in the carbon cycle. Excess of fine sediments may also have adverse effects. It can impair fish spawning by riverbed clogging, disturb foraging efficiency of hunting of river fauna, cause algae and benthos scouring, reduce or inhibit exchanges through the hyporheic region. Accumulation of fine sediments in reservoirs reduces storage capacity. Although fine sediment dynamics has been the focus of many studies, the current knowledge of sediment sources, transfer, and storage is inadequate to address fine sediment dynamics in the landscape. The theoretical derivation of a complete model for suspended sediment transport at the basin scale, incorporating small scale processes of production and transport, is hindered because the underlying mechanisms are produced at different non-similar scales. Availability of long-term reliable data on suspended sediment dynamics is essential to improve our knowledge on transport processes and to develop reliable sediment prediction models. Over the last 60 years, the Yangtze River Commission has been measuring the daily Suspended Sediment Concentration (SSC) at the Pingshan station. This dataset provides a unique opportunity to examine temporal variability and controls of fine sediment dynamics in the Upper Yangtze basin. The objective of this study is to describe temporal variation of fine sediment dynamics at the Pingshan station making use of the extensive sediment monitoring program undertaken at that location. We test several strategies of prediction and forecast applied to the long time series of SSC and streamflow. By changing the base variables between strategies, we improve our understanding of the phenomena driving SSC. Prediction and forecasts are obtained from the various input data sets based on a novel probabilistic data-driven technique, the Generalized Pareto Uncertainty (GPU), which requires very little parametrization. Addressing uncertainty explicitly, this methodology recognizes the stochastic nature of SSC. The GPU was inspired in machine learning concepts and benefits from advances in multi-objective optimization techniques to discard most explicit assumptions about the nature of the uncertainty being modeled. Assumptions that do remain are the need to specify a model for eventual non-stationarity of the series and that there are enough observations to conveniently model the uncertainty. In this contribution, several models are tested with conditioned inputs to focus on specific processes leading affecting SSC. For example, the influence of seasonal and local contributions to SSC can be separated by conditioning the probability estimation on seasonal and local drivers. Probabilistic forecasting models for SSC that account for different drivers of the phenomena are discussed.

  11. It only takes once: The absent-exempt heuristic and reactions to comparison-based sexual risk information

    PubMed Central

    Stock, Michelle L.; Gibbons, Frederick X.; Beekman, Janine B.; Gerrard, Meg

    2015-01-01

    Three studies (N = 545) investigated the effects of social comparison on a type of heuristic called “absent-exempt” (AE; feeling exempt from future risk). Study 1 examined how comparison with an infected peer (comparison target) who was similar or non-similar in terms of sexual risk (number of partners, lack of condom use), influenced willingness and intentions to engage in sex without a condom and conditional perceived vulnerability to a sexually transmitted disease (STD). Participants generally reported lower willingness and higher conditional vulnerability if they compared with a similar-risk level target. However, high-risk students who compared with a low-risk comparison target engaged in what appeared to be AE thinking, reporting the highest willingness and lowest conditional vulnerability. Intentions to have sex without a condom were not influenced. Study 2 included a direct measure of AE thinking, and compared the impact of a low-risk comparison target with a Public Service Announcement (PSA) stating that negative outcomes (e.g., STDs) can happen even to low-risk targets. Among high-risk participants, comparing with the low-risk target led to an increase in AE thinking. As expected, the effects in Studies 1 and 2 were strongest among participants high in tendencies to socially compare. Study 3 explored whether AE thinking could be decreased by encouraging more reasoned processing. Results indicated that asking participants to think about the illogicality of AE thinking reduces AE endorsement and increases STD testing intentions. Findings suggest that comparison-based information can have a stronger influence on health cognitions than analytic-based information (e.g., most PSAs). Implications for dual-processing models of decision-making and their applicability to interventions and health messages are discussed. PMID:26098587

  12. It only takes once: The absent-exempt heuristic and reactions to comparison-based sexual risk information.

    PubMed

    Stock, Michelle L; Gibbons, Frederick X; Beekman, Janine B; Gerrard, Meg

    2015-07-01

    Three studies (N = 545) investigated the effects of social comparison on the "absent-exempt" (AE) heuristic (feeling exempt from future risk). Study 1 examined how comparison with an infected peer (comparison target) who was similar or nonsimilar in terms of sexual risk (number of partners, lack of condom use), influenced willingness and intentions to engage in sex without a condom, and conditional perceived vulnerability to an STD. Participants generally reported lower willingness and higher conditional vulnerability if they compared with a similar-risk level target. However, high-risk students who compared with a low-risk target engaged in what appeared to be AE thinking, reporting the highest willingness and lowest conditional vulnerability. Intentions to have sex without a condom were not influenced. Study 2 included a direct measure of AE thinking and compared the impact of a low-risk comparison target with a Public Service Announcement (PSA) stating that negative outcomes (STDs) can happen even to low-risk targets. Among high-risk participants, comparing with the low-risk target increased AE thinking. The effects in Studies 1 and 2 were strongest among participants high in tendencies to socially compare. Study 3 explored whether AE thinking could be decreased by encouraging more reasoned processing. Results indicated that asking participants to think about the illogicality of AE thinking reduces AE endorsement and increases STD testing intentions. Findings suggest that comparison-based information can have a stronger influence on health cognitions than analytic-based information (e.g., most PSAs). Implications for dual-processing models of decision-making and their applicability to health messages are discussed. (c) 2015 APA, all rights reserved).

  13. Wood Dust Sampling: Field Evaluation of Personal Samplers When Large Particles Are Present

    PubMed Central

    Lee, Taekhee; Harper, Martin; Slaven, James E.; Lee, Kiyoung; Rando, Roy J.; Maples, Elizabeth H.

    2011-01-01

    Recent recommendations for wood dust sampling include sampling according to the inhalable convention of International Organization for Standardization (ISO) 7708 (1995) Air quality—particle size fraction definitions for health-related sampling. However, a specific sampling device is not mandated, and while several samplers have laboratory performance approaching theoretical for an ‘inhalable’ sampler, the best choice of sampler for wood dust is not clear. A side-by-side field study was considered the most practical test of samplers as laboratory performance tests consider overall performance based on a wider range of particle sizes than are commonly encountered in the wood products industry. Seven companies in the wood products industry of the Southeast USA (MS, KY, AL, and WV) participated in this study. The products included hardwood flooring, engineered hardwood flooring, door skins, shutter blinds, kitchen cabinets, plywood, and veneer. The samplers selected were 37-mm closed-face cassette with ACCU-CAP™, Button, CIP10-I, GSP, and Institute of Occupational Medicine. Approximately 30 of each possible pairwise combination of samplers were collected as personal sample sets. Paired samplers of the same type were used to calculate environmental variance that was then used to determine the number of pairs of samples necessary to detect any difference at a specified level of confidence. Total valid sample number was 888 (444 valid pairs). The mass concentration of wood dust ranged from 0.02 to 195 mg m−3. Geometric mean (geometric standard deviation) and arithmetic mean (standard deviation) of wood dust were 0.98 mg m−3 (3.06) and 2.12 mg m−3 (7.74), respectively. One percent of the samples exceeded 15 mg m−3, 6% exceeded 5 mg m−3, and 48% exceeded 1 mg m−3. The number of collected pairs is generally appropriate to detect a 35% difference when outliers (negative mass loadings) are removed. Statistical evaluation of the nonsimilar sampler pair results produced a finding of no significant difference between any pairing of sampler type. A practical consideration for sampling in the USA is that the ACCU-CAP™ is similar to the sampler currently used by the Occupational Safety and Health Administration for purposes of demonstrating compliance with its permissible exposure limit for wood dust, which is the same as for Particles Not Otherwise Regulated, also known as inert dust or nuisance dust (Method PV2121). PMID:21036895

  14. Computational methods for global/local analysis

    NASA Technical Reports Server (NTRS)

    Ransom, Jonathan B.; Mccleary, Susan L.; Aminpour, Mohammad A.; Knight, Norman F., Jr.

    1992-01-01

    Computational methods for global/local analysis of structures which include both uncoupled and coupled methods are described. In addition, global/local analysis methodology for automatic refinement of incompatible global and local finite element models is developed. Representative structural analysis problems are presented to demonstrate the global/local analysis methods.

  15. A Practical, Robust and Fast Method for Location Localization in Range-Based Systems.

    PubMed

    Huang, Shiping; Wu, Zhifeng; Misra, Anil

    2017-12-11

    Location localization technology is used in a number of industrial and civil applications. Real time location localization accuracy is highly dependent on the quality of the distance measurements and efficiency of solving the localization equations. In this paper, we provide a novel approach to solve the nonlinear localization equations efficiently and simultaneously eliminate the bad measurement data in range-based systems. A geometric intersection model was developed to narrow the target search area, where Newton's Method and the Direct Search Method are used to search for the unknown position. Not only does the geometric intersection model offer a small bounded search domain for Newton's Method and the Direct Search Method, but also it can self-correct bad measurement data. The Direct Search Method is useful for the coarse localization or small target search domain, while the Newton's Method can be used for accurate localization. For accurate localization, by utilizing the proposed Modified Newton's Method (MNM), challenges of avoiding the local extrema, singularities, and initial value choice are addressed. The applicability and robustness of the developed method has been demonstrated by experiments with an indoor system.

  16. Finger Vein Recognition Based on Local Directional Code

    PubMed Central

    Meng, Xianjing; Yang, Gongping; Yin, Yilong; Xiao, Rongyang

    2012-01-01

    Finger vein patterns are considered as one of the most promising biometric authentication methods for its security and convenience. Most of the current available finger vein recognition methods utilize features from a segmented blood vessel network. As an improperly segmented network may degrade the recognition accuracy, binary pattern based methods are proposed, such as Local Binary Pattern (LBP), Local Derivative Pattern (LDP) and Local Line Binary Pattern (LLBP). However, the rich directional information hidden in the finger vein pattern has not been fully exploited by the existing local patterns. Inspired by the Webber Local Descriptor (WLD), this paper represents a new direction based local descriptor called Local Directional Code (LDC) and applies it to finger vein recognition. In LDC, the local gradient orientation information is coded as an octonary decimal number. Experimental results show that the proposed method using LDC achieves better performance than methods using LLBP. PMID:23202194

  17. Finger vein recognition based on local directional code.

    PubMed

    Meng, Xianjing; Yang, Gongping; Yin, Yilong; Xiao, Rongyang

    2012-11-05

    Finger vein patterns are considered as one of the most promising biometric authentication methods for its security and convenience. Most of the current available finger vein recognition methods utilize features from a segmented blood vessel network. As an improperly segmented network may degrade the recognition accuracy, binary pattern based methods are proposed, such as Local Binary Pattern (LBP), Local Derivative Pattern (LDP) and Local Line Binary Pattern (LLBP). However, the rich directional information hidden in the finger vein pattern has not been fully exploited by the existing local patterns. Inspired by the Webber Local Descriptor (WLD), this paper represents a new direction based local descriptor called Local Directional Code (LDC) and applies it to finger vein recognition. In LDC, the local gradient orientation information is coded as an octonary decimal number. Experimental results show that the proposed method using LDC achieves better performance than methods using LLBP.

  18. Local-in-Time Adjoint-Based Method for Optimal Control/Design Optimization of Unsteady Compressible Flows

    NASA Technical Reports Server (NTRS)

    Yamaleev, N. K.; Diskin, B.; Nielsen, E. J.

    2009-01-01

    .We study local-in-time adjoint-based methods for minimization of ow matching functionals subject to the 2-D unsteady compressible Euler equations. The key idea of the local-in-time method is to construct a very accurate approximation of the global-in-time adjoint equations and the corresponding sensitivity derivative by using only local information available on each time subinterval. In contrast to conventional time-dependent adjoint-based optimization methods which require backward-in-time integration of the adjoint equations over the entire time interval, the local-in-time method solves local adjoint equations sequentially over each time subinterval. Since each subinterval contains relatively few time steps, the storage cost of the local-in-time method is much lower than that of the global adjoint formulation, thus making the time-dependent optimization feasible for practical applications. The paper presents a detailed comparison of the local- and global-in-time adjoint-based methods for minimization of a tracking functional governed by the Euler equations describing the ow around a circular bump. Our numerical results show that the local-in-time method converges to the same optimal solution obtained with the global counterpart, while drastically reducing the memory cost as compared to the global-in-time adjoint formulation.

  19. Through-the-Wall Localization of a Moving Target by Two Independent Ultra Wideband (UWB) Radar Systems

    PubMed Central

    Kocur, Dušan; Švecová, Mária; Rovňáková, Jana

    2013-01-01

    In the case of through-the-wall localization of moving targets by ultra wideband (UWB) radars, there are applications in which handheld sensors equipped only with one transmitting and two receiving antennas are applied. Sometimes, the radar using such a small antenna array is not able to localize the target with the required accuracy. With a view to improve through-the-wall target localization, cooperative positioning based on a fusion of data retrieved from two independent radar systems can be used. In this paper, the novel method of the cooperative localization referred to as joining intersections of the ellipses is introduced. This method is based on a geometrical interpretation of target localization where the target position is estimated using a properly created cluster of the ellipse intersections representing potential positions of the target. The performance of the proposed method is compared with the direct calculation method and two alternative methods of cooperative localization using data obtained by measurements with the M-sequence UWB radars. The direct calculation method is applied for the target localization by particular radar systems. As alternative methods of cooperative localization, the arithmetic average of the target coordinates estimated by two single independent UWB radars and the Taylor series method is considered. PMID:24021968

  20. Through-the-wall localization of a moving target by two independent ultra wideband (UWB) radar systems.

    PubMed

    Kocur, Dušan; Svecová, Mária; Rovňáková, Jana

    2013-09-09

    In the case of through-the-wall localization of moving targets by ultra wideband (UWB) radars, there are applications in which handheld sensors equipped only with one transmitting and two receiving antennas are applied. Sometimes, the radar using such a small antenna array is not able to localize the target with the required accuracy. With a view to improve through-the-wall target localization, cooperative positioning based on a fusion of data retrieved from two independent radar systems can be used. In this paper, the novel method of the cooperative localization referred to as joining intersections of the ellipses is introduced. This method is based on a geometrical interpretation of target localization where the target position is estimated using a properly created cluster of the ellipse intersections representing potential positions of the target. The performance of the proposed method is compared with the direct calculation method and two alternative methods of cooperative localization using data obtained by measurements with the M-sequence UWB radars. The direct calculation method is applied for the target localization by particular radar systems. As alternative methods of cooperative localization, the arithmetic average of the target coordinates estimated by two single independent UWB radars and the Taylor series method is considered.

  1. Identification of Single-Nucleotide Polymorphic Loci Associated with Biomass Yield under Water Deficit in Alfalfa (Medicago sativa L.) Using Genome-Wide Sequencing and Association Mapping

    PubMed Central

    Yu, Long-Xi

    2017-01-01

    Alfalfa is a worldwide grown forage crop and is important due to its high biomass production and nutritional value. However, the production of alfalfa is challenged by adverse environmental factors such as drought and other stresses. Developing drought resistance alfalfa is an important breeding target for enhancing alfalfa productivity in arid and semi-arid regions. In the present study, we used genotyping-by-sequencing and genome-wide association to identify marker loci associated with biomass yield under drought in the field in a panel of diverse germplasm of alfalfa. A total of 28 markers at 22 genetic loci were associated with yield under water deficit, whereas only four markers associated with the same trait under well-watered condition. Comparisons of marker-trait associations between water deficit and well-watered conditions showed non-similarity except one. Most of the markers were identical across harvest periods within the treatment, although different levels of significance were found among the three harvests. The loci associated with biomass yield under water deficit located throughout all chromosomes in the alfalfa genome agreed with previous reports. Our results suggest that biomass yield under drought is a complex quantitative trait with polygenic inheritance and may involve a different mechanism compared to that of non-stress. BLAST searches of the flanking sequences of the associated loci against DNA databases revealed several stress-responsive genes linked to the drought resistance loci, including leucine-rich repeat receptor-like kinase, B3 DNA-binding domain protein, translation initiation factor IF2, and phospholipase-like protein. With further investigation, those markers closely linked to drought resistance can be used for MAS to accelerate the development of new alfalfa cultivars with improved resistance to drought and other abiotic stresses. PMID:28706532

  2. Interaction of Cd and Zn toxicity for Folsomia candida Willem (Collembola: Isotomidae) in relation to bioavailability in soil

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Van Gestel, C.A.M.; Hensbergen, P.J.

    1997-06-01

    The use of toxicity tests in which each chemical is tested separately is inadequate for assessing the potential risk of complex mixtures of chemicals for soil ecosystems. In the present study, the effects of Cd and Zn, alone or in combination, on the survival, growth, and reproduction of the collembolan Folsomia candida were determined after 2, 4, and 6 weeks of exposure in an artificial soil. The water solubility of Cd in the soil was significantly increased by the presence of Zn, whereas Cd did not affect the water solubility of Zn. In spite of this, uptake of Cd ormore » Zn in the animals was not affected by the presence of the other metal, suggesting that water solubility does not determine the uptake of these metals in F. candida. For both Cd and Zn, reproduction was the most sensitive parameter, with 50% effective concentration (EC50) values of 51 and 683 {micro}g/g dry soil, respectively, after 6 weeks. These values corresponded with internal concentrations of 44 {micro}g Cd/g and 14 {micro}g Zn/g dry soil, respectively. Although a proper comparison of the effects of mixtures of the metals with the effects of the individual metals was sometimes hampered by the nonsimilarity of dose-response relationships, it may be concluded that the effects of the mixture of Cd and Zn on the growth of F. candida are antagonistic (EC50 significantly greater than 1.0 toxic unit), while the effects on reproduction are additive (EC50 = 1.0 toxic unit). Similar conclusions could be drawn for EC50s expressed on the basis of total and water-soluble soil concentrations as well as on the basis of internal concentrations in animals. Analysis of the combined effects of Cd and Zn at the 10% effective concentration level did not change these conclusions.« less

  3. RSS Fingerprint Based Indoor Localization Using Sparse Representation with Spatio-Temporal Constraint

    PubMed Central

    Piao, Xinglin; Zhang, Yong; Li, Tingshu; Hu, Yongli; Liu, Hao; Zhang, Ke; Ge, Yun

    2016-01-01

    The Received Signal Strength (RSS) fingerprint-based indoor localization is an important research topic in wireless network communications. Most current RSS fingerprint-based indoor localization methods do not explore and utilize the spatial or temporal correlation existing in fingerprint data and measurement data, which is helpful for improving localization accuracy. In this paper, we propose an RSS fingerprint-based indoor localization method by integrating the spatio-temporal constraints into the sparse representation model. The proposed model utilizes the inherent spatial correlation of fingerprint data in the fingerprint matching and uses the temporal continuity of the RSS measurement data in the localization phase. Experiments on the simulated data and the localization tests in the real scenes show that the proposed method improves the localization accuracy and stability effectively compared with state-of-the-art indoor localization methods. PMID:27827882

  4. Local Observed-Score Kernel Equating

    ERIC Educational Resources Information Center

    Wiberg, Marie; van der Linden, Wim J.; von Davier, Alina A.

    2014-01-01

    Three local observed-score kernel equating methods that integrate methods from the local equating and kernel equating frameworks are proposed. The new methods were compared with their earlier counterparts with respect to such measures as bias--as defined by Lord's criterion of equity--and percent relative error. The local kernel item response…

  5. Foreign English Language Teachers' Local Pedagogy

    ERIC Educational Resources Information Center

    Eusafzai, Hamid Ali Khan

    2015-01-01

    ELT methods have been criticized for being limited and inadequate. Postmethod pedagogy has been offered as an alternate to these methods. The postmethod pedagogy emphasises localization of pedagogy and celebrates local culture, teachers and knowledge. Localizing pedagogy is easy for local teachers as knowledge and understanding of the local comes…

  6. A Modified Magnetic Gradient Contraction Based Method for Ferromagnetic Target Localization

    PubMed Central

    Wang, Chen; Zhang, Xiaojuan; Qu, Xiaodong; Pan, Xiao; Fang, Guangyou; Chen, Luzhao

    2016-01-01

    The Scalar Triangulation and Ranging (STAR) method, which is based upon the unique properties of magnetic gradient contraction, is a high real-time ferromagnetic target localization method. Only one measurement point is required in the STAR method and it is not sensitive to changes in sensing platform orientation. However, the localization accuracy of the method is limited by the asphericity errors and the inaccurate value of position leads to larger errors in the estimation of magnetic moment. To improve the localization accuracy, a modified STAR method is proposed. In the proposed method, the asphericity errors of the traditional STAR method are compensated with an iterative algorithm. The proposed method has a fast convergence rate which meets the requirement of high real-time localization. Simulations and field experiments have been done to evaluate the performance of the proposed method. The results indicate that target parameters estimated by the modified STAR method are more accurate than the traditional STAR method. PMID:27999322

  7. Global/local stress analysis of composite panels

    NASA Technical Reports Server (NTRS)

    Ransom, Jonathan B.; Knight, Norman F., Jr.

    1989-01-01

    A method for performing a global/local stress analysis is described, and its capabilities are demonstrated. The method employs spline interpolation functions which satisfy the linear plate bending equation to determine displacements and rotations from a global model which are used as boundary conditions for the local model. Then, the local model is analyzed independent of the global model of the structure. This approach can be used to determine local, detailed stress states for specific structural regions using independent, refined local models which exploit information from less-refined global models. The method presented is not restricted to having a priori knowledge of the location of the regions requiring local detailed stress analysis. This approach also reduces the computational effort necessary to obtain the detailed stress state. Criteria for applying the method are developed. The effectiveness of the method is demonstrated using a classical stress concentration problem and a graphite-epoxy blade-stiffened panel with a discontinuous stiffener.

  8. Global/local stress analysis of composite structures. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Ransom, Jonathan B.

    1989-01-01

    A method for performing a global/local stress analysis is described and its capabilities are demonstrated. The method employs spline interpolation functions which satisfy the linear plate bending equation to determine displacements and rotations from a global model which are used as boundary conditions for the local model. Then, the local model is analyzed independent of the global model of the structure. This approach can be used to determine local, detailed stress states for specific structural regions using independent, refined local models which exploit information from less-refined global models. The method presented is not restricted to having a priori knowledge of the location of the regions requiring local detailed stress analysis. This approach also reduces the computational effort necessary to obtain the detailed stress state. Criteria for applying the method are developed. The effectiveness of the method is demonstrated using a classical stress concentration problem and a graphite-epoxy blade-stiffened panel with a discontinuous stiffener.

  9. Local/non-local regularized image segmentation using graph-cuts: application to dynamic and multispectral MRI.

    PubMed

    Hanson, Erik A; Lundervold, Arvid

    2013-11-01

    Multispectral, multichannel, or time series image segmentation is important for image analysis in a wide range of applications. Regularization of the segmentation is commonly performed using local image information causing the segmented image to be locally smooth or piecewise constant. A new spatial regularization method, incorporating non-local information, was developed and tested. Our spatial regularization method applies to feature space classification in multichannel images such as color images and MR image sequences. The spatial regularization involves local edge properties, region boundary minimization, as well as non-local similarities. The method is implemented in a discrete graph-cut setting allowing fast computations. The method was tested on multidimensional MRI recordings from human kidney and brain in addition to simulated MRI volumes. The proposed method successfully segment regions with both smooth and complex non-smooth shapes with a minimum of user interaction.

  10. Effects of local anaesthesia or local anaesthesia plus a non-steroidal anti-inflammatory drug on the acute cortisol response of calves to five different methods of castration.

    PubMed

    Stafford, K J; Mellor, D J; Todd, S E; Bruce, R A; Ward, R N

    2002-08-01

    The cortisol response of calves to different methods of castration (ring, band, surgical, clamp) with or without local anaesthetic, or local anaesthetic plus a non-steroidal anti-inflammatory drug were recorded. All methods of castration caused a significant cortisol response and by inference pain and distress. Band castration caused a greater cortisol response than ring castration but the responses were eliminated by local anaesthetic. The cortisol response to surgical castration, by traction on the spermatic cords or by cutting across them with an emasculator, was not diminished by local anaesthetic but when ketoprofen was given with local anaesthetic the cortisol response was eliminated. Local anaesthetic did reduce the behavioural response to cutting the scrotum and handling the testes. Clamp castration caused the smallest cortisol response which was reduced or eliminated by local anaesthetic or local anesthetic plus ketoprofen respectively, but this method of castration was not always successful.

  11. LOCALIZER: subcellular localization prediction of both plant and effector proteins in the plant cell

    PubMed Central

    Sperschneider, Jana; Catanzariti, Ann-Maree; DeBoer, Kathleen; Petre, Benjamin; Gardiner, Donald M.; Singh, Karam B.; Dodds, Peter N.; Taylor, Jennifer M.

    2017-01-01

    Pathogens secrete effector proteins and many operate inside plant cells to enable infection. Some effectors have been found to enter subcellular compartments by mimicking host targeting sequences. Although many computational methods exist to predict plant protein subcellular localization, they perform poorly for effectors. We introduce LOCALIZER for predicting plant and effector protein localization to chloroplasts, mitochondria, and nuclei. LOCALIZER shows greater prediction accuracy for chloroplast and mitochondrial targeting compared to other methods for 652 plant proteins. For 107 eukaryotic effectors, LOCALIZER outperforms other methods and predicts a previously unrecognized chloroplast transit peptide for the ToxA effector, which we show translocates into tobacco chloroplasts. Secretome-wide predictions and confocal microscopy reveal that rust fungi might have evolved multiple effectors that target chloroplasts or nuclei. LOCALIZER is the first method for predicting effector localisation in plants and is a valuable tool for prioritizing effector candidates for functional investigations. LOCALIZER is available at http://localizer.csiro.au/. PMID:28300209

  12. Radiographic localization of unerupted teeth: further findings about the vertical tube shift method and other localization techniques.

    PubMed

    Jacobs, S G

    2000-10-01

    The parallax method (image/tube shift method, Clark's rule, Richards' buccal object rule) is recommended to localize unerupted teeth. Richards' contribution to the development of the parallax method is discussed. The favored method for localization uses a rotational panoramic radiograph in combination with an occlusal radiograph involving a vertical shift of the x-ray tube. The use of this combination when localizing teeth and supernumeraries in the premolar region is illustrated. When taking an occlusal radiograph to localize an unerupted maxillary canine, clinical situations are presented where modification of the vertical angulation of the tube of 70 degrees to 75 degrees or of the horizontal position of the tube is warranted. The limitations of axial (true, cross-sectional, vertex) occlusal radiographs are also explored.

  13. Method of preliminary localization of the iris in biometric access control systems

    NASA Astrophysics Data System (ADS)

    Minacova, N.; Petrov, I.

    2015-10-01

    This paper presents a method of preliminary localization of the iris, based on the stable brightness features of the iris in images of the eye. In tests on images of eyes from publicly available databases method showed good accuracy and speed compared to existing methods preliminary localization.

  14. PLPD: reliable protein localization prediction from imbalanced and overlapped datasets

    PubMed Central

    Lee, KiYoung; Kim, Dae-Won; Na, DoKyun; Lee, Kwang H.; Lee, Doheon

    2006-01-01

    Subcellular localization is one of the key functional characteristics of proteins. An automatic and efficient prediction method for the protein subcellular localization is highly required owing to the need for large-scale genome analysis. From a machine learning point of view, a dataset of protein localization has several characteristics: the dataset has too many classes (there are more than 10 localizations in a cell), it is a multi-label dataset (a protein may occur in several different subcellular locations), and it is too imbalanced (the number of proteins in each localization is remarkably different). Even though many previous works have been done for the prediction of protein subcellular localization, none of them tackles effectively these characteristics at the same time. Thus, a new computational method for protein localization is eventually needed for more reliable outcomes. To address the issue, we present a protein localization predictor based on D-SVDD (PLPD) for the prediction of protein localization, which can find the likelihood of a specific localization of a protein more easily and more correctly. Moreover, we introduce three measurements for the more precise evaluation of a protein localization predictor. As the results of various datasets which are made from the experiments of Huh et al. (2003), the proposed PLPD method represents a different approach that might play a complimentary role to the existing methods, such as Nearest Neighbor method and discriminate covariant method. Finally, after finding a good boundary for each localization using the 5184 classified proteins as training data, we predicted 138 proteins whose subcellular localizations could not be clearly observed by the experiments of Huh et al. (2003). PMID:16966337

  15. Adaptive Localization of Focus Point Regions via Random Patch Probabilistic Density from Whole-Slide, Ki-67-Stained Brain Tumor Tissue

    PubMed Central

    Alomari, Yazan M.; MdZin, Reena Rahayu

    2015-01-01

    Analysis of whole-slide tissue for digital pathology images has been clinically approved to provide a second opinion to pathologists. Localization of focus points from Ki-67-stained histopathology whole-slide tissue microscopic images is considered the first step in the process of proliferation rate estimation. Pathologists use eye pooling or eagle-view techniques to localize the highly stained cell-concentrated regions from the whole slide under microscope, which is called focus-point regions. This procedure leads to a high variety of interpersonal observations and time consuming, tedious work and causes inaccurate findings. The localization of focus-point regions can be addressed as a clustering problem. This paper aims to automate the localization of focus-point regions from whole-slide images using the random patch probabilistic density method. Unlike other clustering methods, random patch probabilistic density method can adaptively localize focus-point regions without predetermining the number of clusters. The proposed method was compared with the k-means and fuzzy c-means clustering methods. Our proposed method achieves a good performance, when the results were evaluated by three expert pathologists. The proposed method achieves an average false-positive rate of 0.84% for the focus-point region localization error. Moreover, regarding RPPD used to localize tissue from whole-slide images, 228 whole-slide images have been tested; 97.3% localization accuracy was achieved. PMID:25793010

  16. Sound source localization method in an environment with flow based on Amiet-IMACS

    NASA Astrophysics Data System (ADS)

    Wei, Long; Li, Min; Qin, Sheng; Fu, Qiang; Yang, Debin

    2017-05-01

    A sound source localization method is proposed to localize and analyze the sound source in an environment with airflow. It combines the improved mapping of acoustic correlated sources (IMACS) method and Amiet's method, and is called Amiet-IMACS. It can localize uncorrelated and correlated sound sources with airflow. To implement this approach, Amiet's method is used to correct the sound propagation path in 3D, which improves the accuracy of the array manifold matrix and decreases the position error of the localized source. Then, the mapping of acoustic correlated sources (MACS) method, which is as a high-resolution sound source localization algorithm, is improved by self-adjusting the constraint parameter at each irritation process to increase convergence speed. A sound source localization experiment using a pair of loud speakers in an anechoic wind tunnel under different flow speeds is conducted. The experiment exhibits the advantage of Amiet-IMACS in localizing a more accurate sound source position compared with implementing IMACS alone in an environment with flow. Moreover, the aerodynamic noise produced by a NASA EPPLER 862 STRUT airfoil model in airflow with a velocity of 80 m/s is localized using the proposed method, which further proves its effectiveness in a flow environment. Finally, the relationship between the source position of this airfoil model and its frequency, along with its generation mechanism, is determined and interpreted.

  17. Algebraic Algorithm Design and Local Search

    DTIC Science & Technology

    1996-12-01

    method for performing algorithm design that is more purely algebraic than that of KIDS. This method is then applied to local search. Local search is a...synthesis. Our approach was to follow KIDS in spirit, but to adopt a pure algebraic formalism, supported by Kestrel’s SPECWARE environment (79), that...design was developed that is more purely algebraic than that of KIDS. This method was then applied to local search. A general theory of local search was

  18. An Unsupervised kNN Method to Systematically Detect Changes in Protein Localization in High-Throughput Microscopy Images.

    PubMed

    Lu, Alex Xijie; Moses, Alan M

    2016-01-01

    Despite the importance of characterizing genes that exhibit subcellular localization changes between conditions in proteome-wide imaging experiments, many recent studies still rely upon manual evaluation to assess the results of high-throughput imaging experiments. We describe and demonstrate an unsupervised k-nearest neighbours method for the detection of localization changes. Compared to previous classification-based supervised change detection methods, our method is much simpler and faster, and operates directly on the feature space to overcome limitations in needing to manually curate training sets that may not generalize well between screens. In addition, the output of our method is flexible in its utility, generating both a quantitatively ranked list of localization changes that permit user-defined cut-offs, and a vector for each gene describing feature-wise direction and magnitude of localization changes. We demonstrate that our method is effective at the detection of localization changes using the Δrpd3 perturbation in Saccharomyces cerevisiae, where we capture 71.4% of previously known changes within the top 10% of ranked genes, and find at least four new localization changes within the top 1% of ranked genes. The results of our analysis indicate that simple unsupervised methods may be able to identify localization changes in images without laborious manual image labelling steps.

  19. Small-Tip-Angle Spokes Pulse Design Using Interleaved Greedy and Local Optimization Methods

    PubMed Central

    Grissom, William A.; Khalighi, Mohammad-Mehdi; Sacolick, Laura I.; Rutt, Brian K.; Vogel, Mika W.

    2013-01-01

    Current spokes pulse design methods can be grouped into methods based either on sparse approximation or on iterative local (gradient descent-based) optimization of the transverse-plane spatial frequency locations visited by the spokes. These two classes of methods have complementary strengths and weaknesses: sparse approximation-based methods perform an efficient search over a large swath of candidate spatial frequency locations but most are incompatible with off-resonance compensation, multifrequency designs, and target phase relaxation, while local methods can accommodate off-resonance and target phase relaxation but are sensitive to initialization and suboptimal local cost function minima. This article introduces a method that interleaves local iterations, which optimize the radiofrequency pulses, target phase patterns, and spatial frequency locations, with a greedy method to choose new locations. Simulations and experiments at 3 and 7 T show that the method consistently produces single- and multifrequency spokes pulses with lower flip angle inhomogeneity compared to current methods. PMID:22392822

  20. Wavelet-based adaptive thresholding method for image segmentation

    NASA Astrophysics Data System (ADS)

    Chen, Zikuan; Tao, Yang; Chen, Xin; Griffis, Carl

    2001-05-01

    A nonuniform background distribution may cause a global thresholding method to fail to segment objects. One solution is using a local thresholding method that adapts to local surroundings. In this paper, we propose a novel local thresholding method for image segmentation, using multiscale threshold functions obtained by wavelet synthesis with weighted detail coefficients. In particular, the coarse-to- fine synthesis with attenuated detail coefficients produces a threshold function corresponding to a high-frequency- reduced signal. This wavelet-based local thresholding method adapts to both local size and local surroundings, and its implementation can take advantage of the fast wavelet algorithm. We applied this technique to physical contaminant detection for poultry meat inspection using x-ray imaging. Experiments showed that inclusion objects in deboned poultry could be extracted at multiple resolutions despite their irregular sizes and uneven backgrounds.

  1. Global/local methods research using the CSM testbed

    NASA Technical Reports Server (NTRS)

    Knight, Norman F., Jr.; Ransom, Jonathan B.; Griffin, O. Hayden, Jr.; Thompson, Danniella M.

    1990-01-01

    Research activities in global/local stress analysis are described including both two- and three-dimensional analysis methods. These methods are being developed within a common structural analysis framework. Representative structural analysis problems are presented to demonstrate the global/local methodologies being developed.

  2. Global/local methods research using a common structural analysis framework

    NASA Technical Reports Server (NTRS)

    Knight, Norman F., Jr.; Ransom, Jonathan B.; Griffin, O. H., Jr.; Thompson, Danniella M.

    1991-01-01

    Methodologies for global/local stress analysis are described including both two- and three-dimensional analysis methods. These methods are being developed within a common structural analysis framework. Representative structural analysis problems are presented to demonstrate the global/local methodologies being developed.

  3. A Tomographic Method for the Reconstruction of Local Probability Density Functions

    NASA Technical Reports Server (NTRS)

    Sivathanu, Y. R.; Gore, J. P.

    1993-01-01

    A method of obtaining the probability density function (PDF) of local properties from path integrated measurements is described. The approach uses a discrete probability function (DPF) method to infer the PDF of the local extinction coefficient from measurements of the PDFs of the path integrated transmittance. The local PDFs obtained using the method are compared with those obtained from direct intrusive measurements in propylene/air and ethylene/air diffusion flames. The results of this comparison are good.

  4. Formulation analysis and computation of an optimization-based local-to-nonlocal coupling method.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    D'Elia, Marta; Bochev, Pavel Blagoveston

    2017-01-01

    In this paper, we present an optimization-based coupling method for local and nonlocal continuum models. Our approach couches the coupling of the models into a control problem where the states are the solutions of the nonlocal and local equations, the objective is to minimize their mismatch on the overlap of the local and nonlocal problem domains, and the virtual controls are the nonlocal volume constraint and the local boundary condition. We present the method in the context of Local-to-Nonlocal di usion coupling. Numerical examples illustrate the theoretical properties of the approach.

  5. Analysis on accuracy improvement of rotor-stator rubbing localization based on acoustic emission beamforming method.

    PubMed

    He, Tian; Xiao, Denghong; Pan, Qiang; Liu, Xiandong; Shan, Yingchun

    2014-01-01

    This paper attempts to introduce an improved acoustic emission (AE) beamforming method to localize rotor-stator rubbing fault in rotating machinery. To investigate the propagation characteristics of acoustic emission signals in casing shell plate of rotating machinery, the plate wave theory is used in a thin plate. A simulation is conducted and its result shows the localization accuracy of beamforming depends on multi-mode, dispersion, velocity and array dimension. In order to reduce the effect of propagation characteristics on the source localization, an AE signal pre-process method is introduced by combining plate wave theory and wavelet packet transform. And the revised localization velocity to reduce effect of array size is presented. The accuracy of rubbing localization based on beamforming and the improved method of present paper are compared by the rubbing test carried on a test table of rotating machinery. The results indicate that the improved method can localize rub fault effectively. Copyright © 2013 Elsevier B.V. All rights reserved.

  6. Similarity indices based on link weight assignment for link prediction of unweighted complex networks

    NASA Astrophysics Data System (ADS)

    Liu, Shuxin; Ji, Xinsheng; Liu, Caixia; Bai, Yi

    2017-01-01

    Many link prediction methods have been proposed for predicting the likelihood that a link exists between two nodes in complex networks. Among these methods, similarity indices are receiving close attention. Most similarity-based methods assume that the contribution of links with different topological structures is the same in the similarity calculations. This paper proposes a local weighted method, which weights the strength of connection between each pair of nodes. Based on the local weighted method, six local weighted similarity indices extended from unweighted similarity indices (including Common Neighbor (CN), Adamic-Adar (AA), Resource Allocation (RA), Salton, Jaccard and Local Path (LP) index) are proposed. Empirical study has shown that the local weighted method can significantly improve the prediction accuracy of these unweighted similarity indices and that in sparse and weakly clustered networks, the indices perform even better.

  7. Local blur analysis and phase error correction method for fringe projection profilometry systems.

    PubMed

    Rao, Li; Da, Feipeng

    2018-05-20

    We introduce a flexible error correction method for fringe projection profilometry (FPP) systems in the presence of local blur phenomenon. Local blur caused by global light transport such as camera defocus, projector defocus, and subsurface scattering will cause significant systematic errors in FPP systems. Previous methods, which adopt high-frequency patterns to separate the direct and global components, fail when the global light phenomenon occurs locally. In this paper, the influence of local blur on phase quality is thoroughly analyzed, and a concise error correction method is proposed to compensate the phase errors. For defocus phenomenon, this method can be directly applied. With the aid of spatially varying point spread functions and local frontal plane assumption, experiments show that the proposed method can effectively alleviate the system errors and improve the final reconstruction accuracy in various scenes. For a subsurface scattering scenario, if the translucent object is dominated by multiple scattering, the proposed method can also be applied to correct systematic errors once the bidirectional scattering-surface reflectance distribution function of the object material is measured.

  8. A Novel Method of Localization for Moving Objects with an Alternating Magnetic Field

    PubMed Central

    Gao, Xiang; Yan, Shenggang; Li, Bin

    2017-01-01

    Magnetic detection technology has wide applications in the fields of geological exploration, biomedical treatment, wreck removal and localization of unexploded ordinance. A large number of methods have been developed to locate targets with static magnetic fields, however, the relation between the problem of localization of moving objectives with alternating magnetic fields and the localization with a static magnetic field is rarely studied. A novel method of target localization based on coherent demodulation was proposed in this paper. The problem of localization of moving objects with an alternating magnetic field was transformed into the localization with a static magnetic field. The Levenberg-Marquardt (L-M) algorithm was applied to calculate the position of the target with magnetic field data measured by a single three-component magnetic sensor. Theoretical simulation and experimental results demonstrate the effectiveness of the proposed method. PMID:28430153

  9. Local shear stress and its correlation with local volume fraction in concentrated non-Brownian suspensions: Lattice Boltzmann simulation

    NASA Astrophysics Data System (ADS)

    Lee, Young Ki; Ahn, Kyung Hyun; Lee, Seung Jong

    2014-12-01

    The local shear stress of non-Brownian suspensions was investigated using the lattice Boltzmann method coupled with the smoothed profile method. Previous studies have only focused on the bulk rheology of complex fluids because the local rheology of complex fluids was not accessible due to technical limitations. In this study, the local shear stress of two-dimensional solid particle suspensions in Couette flow was investigated with the method of planes to correlate non-Newtonian fluid behavior with the structural evolution of concentrated particle suspensions. Shear thickening was successfully captured for highly concentrated suspensions at high particle Reynolds number, and both the local rheology and local structure of the suspensions were analyzed. It was also found that the linear correlation between the local particle stress and local particle volume fraction was dramatically reduced during shear thickening. These results clearly show how the change in local structure of suspensions influences the local and bulk rheology of the suspensions.

  10. Distributed processing of a GPS receiver network for a regional ionosphere map

    NASA Astrophysics Data System (ADS)

    Choi, Kwang Ho; Hoo Lim, Joon; Yoo, Won Jae; Lee, Hyung Keun

    2018-01-01

    This paper proposes a distributed processing method applicable to GPS receivers in a network to generate a regional ionosphere map accurately and reliably. For accuracy, the proposed method is operated by multiple local Kalman filters and Kriging estimators. Each local Kalman filter is applied to a dual-frequency receiver to estimate the receiver’s differential code bias and vertical ionospheric delays (VIDs) at different ionospheric pierce points. The Kriging estimator selects and combines several VID estimates provided by the local Kalman filters to generate the VID estimate at each ionospheric grid point. For reliability, the proposed method uses receiver fault detectors and satellite fault detectors. Each receiver fault detector compares the VID estimates of the same local area provided by different local Kalman filters. Each satellite fault detector compares the VID estimate of each local area with that projected from the other local areas. Compared with the traditional centralized processing method, the proposed method is advantageous in that it considerably reduces the computational burden of each single Kalman filter and enables flexible fault detection, isolation, and reconfiguration capability. To evaluate the performance of the proposed method, several experiments with field collected measurements were performed.

  11. Omni-Directional Scanning Localization Method of a Mobile Robot Based on Ultrasonic Sensors.

    PubMed

    Mu, Wei-Yi; Zhang, Guang-Peng; Huang, Yu-Mei; Yang, Xin-Gang; Liu, Hong-Yan; Yan, Wen

    2016-12-20

    Improved ranging accuracy is obtained by the development of a novel ultrasonic sensor ranging algorithm, unlike the conventional ranging algorithm, which considers the divergence angle and the incidence angle of the ultrasonic sensor synchronously. An ultrasonic sensor scanning method is developed based on this algorithm for the recognition of an inclined plate and to obtain the localization of the ultrasonic sensor relative to the inclined plate reference frame. The ultrasonic sensor scanning method is then leveraged for the omni-directional localization of a mobile robot, where the ultrasonic sensors are installed on a mobile robot and follow the spin of the robot, the inclined plate is recognized and the position and posture of the robot are acquired with respect to the coordinate system of the inclined plate, realizing the localization of the robot. Finally, the localization method is implemented into an omni-directional scanning localization experiment with the independently researched and developed mobile robot. Localization accuracies of up to ±3.33 mm for the front, up to ±6.21 for the lateral and up to ±0.20° for the posture are obtained, verifying the correctness and effectiveness of the proposed localization method.

  12. Development of parallel algorithms for electrical power management in space applications

    NASA Technical Reports Server (NTRS)

    Berry, Frederick C.

    1989-01-01

    The application of parallel techniques for electrical power system analysis is discussed. The Newton-Raphson method of load flow analysis was used along with the decomposition-coordination technique to perform load flow analysis. The decomposition-coordination technique enables tasks to be performed in parallel by partitioning the electrical power system into independent local problems. Each independent local problem represents a portion of the total electrical power system on which a loan flow analysis can be performed. The load flow analysis is performed on these partitioned elements by using the Newton-Raphson load flow method. These independent local problems will produce results for voltage and power which can then be passed to the coordinator portion of the solution procedure. The coordinator problem uses the results of the local problems to determine if any correction is needed on the local problems. The coordinator problem is also solved by an iterative method much like the local problem. The iterative method for the coordination problem will also be the Newton-Raphson method. Therefore, each iteration at the coordination level will result in new values for the local problems. The local problems will have to be solved again along with the coordinator problem until some convergence conditions are met.

  13. Computationally efficient method for localizing the spiral rotor source using synthetic intracardiac electrograms during atrial fibrillation.

    PubMed

    Shariat, M H; Gazor, S; Redfearn, D

    2015-08-01

    Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is an extremely costly public health problem. Catheter-based ablation is a common minimally invasive procedure to treat AF. Contemporary mapping methods are highly dependent on the accuracy of anatomic localization of rotor sources within the atria. In this paper, using simulated atrial intracardiac electrograms (IEGMs) during AF, we propose a computationally efficient method for localizing the tip of the electrical rotor with an Archimedean/arithmetic spiral wavefront. The proposed method deploys the locations of electrodes of a catheter and their IEGMs activation times to estimate the unknown parameters of the spiral wavefront including its tip location. The proposed method is able to localize the spiral as soon as the wave hits three electrodes of the catheter. Our simulation results show that the method can efficiently localize the spiral wavefront that rotates either clockwise or counterclockwise.

  14. Methods and strategies of object localization

    NASA Technical Reports Server (NTRS)

    Shao, Lejun; Volz, Richard A.

    1989-01-01

    An important property of an intelligent robot is to be able to determine the location of an object in 3-D space. A general object localization system structure is proposed, some important issues on localization discussed, and an overview given for current available object localization algorithms and systems. The algorithms reviewed are characterized by their feature extracting and matching strategies; the range finding methods; the types of locatable objects; and the mathematical formulating methods.

  15. 3-D localization of virtual sound sources: effects of visual environment, pointing method, and training.

    PubMed

    Majdak, Piotr; Goupell, Matthew J; Laback, Bernhard

    2010-02-01

    The ability to localize sound sources in three-dimensional space was tested in humans. In Experiment 1, naive subjects listened to noises filtered with subject-specific head-related transfer functions. The tested conditions included the pointing method (head or manual pointing) and the visual environment (VE; darkness or virtual VE). The localization performance was not significantly different between the pointing methods. The virtual VE significantly improved the horizontal precision and reduced the number of front-back confusions. These results show the benefit of using a virtual VE in sound localization tasks. In Experiment 2, subjects were provided with sound localization training. Over the course of training, the performance improved for all subjects, with the largest improvements occurring during the first 400 trials. The improvements beyond the first 400 trials were smaller. After the training, there was still no significant effect of pointing method, showing that the choice of either head- or manual-pointing method plays a minor role in sound localization performance. The results of Experiment 2 reinforce the importance of perceptual training for at least 400 trials in sound localization studies.

  16. Kernel PLS Estimation of Single-trial Event-related Potentials

    NASA Technical Reports Server (NTRS)

    Rosipal, Roman; Trejo, Leonard J.

    2004-01-01

    Nonlinear kernel partial least squaes (KPLS) regressior, is a novel smoothing approach to nonparametric regression curve fitting. We have developed a KPLS approach to the estimation of single-trial event related potentials (ERPs). For improved accuracy of estimation, we also developed a local KPLS method for situations in which there exists prior knowledge about the approximate latency of individual ERP components. To assess the utility of the KPLS approach, we compared non-local KPLS and local KPLS smoothing with other nonparametric signal processing and smoothing methods. In particular, we examined wavelet denoising, smoothing splines, and localized smoothing splines. We applied these methods to the estimation of simulated mixtures of human ERPs and ongoing electroencephalogram (EEG) activity using a dipole simulator (BESA). In this scenario we considered ongoing EEG to represent spatially and temporally correlated noise added to the ERPs. This simulation provided a reasonable but simplified model of real-world ERP measurements. For estimation of the simulated single-trial ERPs, local KPLS provided a level of accuracy that was comparable with or better than the other methods. We also applied the local KPLS method to the estimation of human ERPs recorded in an experiment on co,onitive fatigue. For these data, the local KPLS method provided a clear improvement in visualization of single-trial ERPs as well as their averages. The local KPLS method may serve as a new alternative to the estimation of single-trial ERPs and improvement of ERP averages.

  17. Recursive grid partitioning on a cortical surface model: an optimized technique for the localization of implanted subdural electrodes.

    PubMed

    Pieters, Thomas A; Conner, Christopher R; Tandon, Nitin

    2013-05-01

    Precise localization of subdural electrodes (SDEs) is essential for the interpretation of data from intracranial electrocorticography recordings. Blood and fluid accumulation underneath the craniotomy flap leads to a nonlinear deformation of the brain surface and of the SDE array on postoperative CT scans and adversely impacts the accurate localization of electrodes located underneath the craniotomy. Older methods that localize electrodes based on their identification on a postimplantation CT scan with coregistration to a preimplantation MR image can result in significant problems with accuracy of the electrode localization. The authors report 3 novel methods that rely on the creation of a set of 3D mesh models to depict the pial surface and a smoothed pial envelope. Two of these new methods are designed to localize electrodes, and they are compared with 6 methods currently in use to determine their relative accuracy and reliability. The first method involves manually localizing each electrode using digital photographs obtained at surgery. This is highly accurate, but requires time intensive, operator-dependent input. The second uses 4 electrodes localized manually in conjunction with an automated, recursive partitioning technique to localize the entire electrode array. The authors evaluated the accuracy of previously published methods by applying the methods to their data and comparing them against the photograph-based localization. Finally, the authors further enhanced the usability of these methods by using automatic parcellation techniques to assign anatomical labels to individual electrodes as well as by generating an inflated cortical surface model while still preserving electrode locations relative to the cortical anatomy. The recursive grid partitioning had the least error compared with older methods (672 electrodes, 6.4-mm maximum electrode error, 2.0-mm mean error, p < 10(-18)). The maximum errors derived using prior methods of localization ranged from 8.2 to 11.7 mm for an individual electrode, with mean errors ranging between 2.9 and 4.1 mm depending on the method used. The authors also noted a larger error in all methods that used CT scans alone to localize electrodes compared with those that used both postoperative CT and postoperative MRI. The large mean errors reported with these methods are liable to affect intermodal data comparisons (for example, with functional mapping techniques) and may impact surgical decision making. The authors have presented several aspects of using new techniques to visualize electrodes implanted for localizing epilepsy. The ability to use automated labeling schemas to denote which gyrus a particular electrode overlies is potentially of great utility in planning resections and in corroborating the results of extraoperative stimulation mapping. Dilation of the pial mesh model provides, for the first time, a sense of the cortical surface not sampled by the electrode, and the potential roles this "electrophysiologically hidden" cortex may play in both eloquent function and seizure onset.

  18. 47 CFR Appendix to Part 52 - Deployment Schedule for Long-Term Database Methods for Local Number Portability

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 3 2012-10-01 2012-10-01 false Deployment Schedule for Long-Term Database Methods for Local Number Portability Appendix to Part 52 Telecommunication FEDERAL COMMUNICATIONS...—Deployment Schedule for Long-Term Database Methods for Local Number Portability Implementation must be...

  19. 47 CFR Appendix to Part 52 - Deployment Schedule for Long-Term Database Methods for Local Number Portability

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 3 2013-10-01 2013-10-01 false Deployment Schedule for Long-Term Database Methods for Local Number Portability Appendix to Part 52 Telecommunication FEDERAL COMMUNICATIONS...—Deployment Schedule for Long-Term Database Methods for Local Number Portability Implementation must be...

  20. 47 CFR Appendix to Part 52 - Deployment Schedule for Long-Term Database Methods for Local Number Portability

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Deployment Schedule for Long-Term Database Methods for Local Number Portability Appendix to Part 52 Telecommunication FEDERAL COMMUNICATIONS...—Deployment Schedule for Long-Term Database Methods for Local Number Portability Implementation must be...

  1. 47 CFR Appendix to Part 52 - Deployment Schedule for Long-Term Database Methods for Local Number Portability

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 3 2014-10-01 2014-10-01 false Deployment Schedule for Long-Term Database Methods for Local Number Portability Appendix to Part 52 Telecommunication FEDERAL COMMUNICATIONS...—Deployment Schedule for Long-Term Database Methods for Local Number Portability Implementation must be...

  2. 47 CFR Appendix to Part 52 - Deployment Schedule for Long-Term Database Methods for Local Number Portability

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Deployment Schedule for Long-Term Database Methods for Local Number Portability Appendix to Part 52 Telecommunication FEDERAL COMMUNICATIONS...—Deployment Schedule for Long-Term Database Methods for Local Number Portability Implementation must be...

  3. Impact localization in dispersive waveguides based on energy-attenuation of waves with the traveled distance

    NASA Astrophysics Data System (ADS)

    Alajlouni, Sa'ed; Albakri, Mohammad; Tarazaga, Pablo

    2018-05-01

    An algorithm is introduced to solve the general multilateration (source localization) problem in a dispersive waveguide. The algorithm is designed with the intention of localizing impact forces in a dispersive floor, and can potentially be used to localize and track occupants in a building using vibration sensors connected to the lower surface of the walking floor. The lower the wave frequencies generated by the impact force, the more accurate the localization is expected to be. An impact force acting on a floor, generates a seismic wave that gets distorted as it travels away from the source. This distortion is noticeable even over relatively short traveled distances, and is mainly caused by the dispersion phenomenon among other reasons, therefore using conventional localization/multilateration methods will produce localization error values that are highly variable and occasionally large. The proposed localization approach is based on the fact that the wave's energy, calculated over some time window, decays exponentially as the wave travels away from the source. Although localization methods that assume exponential decay exist in the literature (in the field of wireless communications), these methods have only been considered for wave propagation in non-dispersive media, in addition to the limiting assumption required by these methods that the source must not coincide with a sensor location. As a result, these methods cannot be applied to the indoor localization problem in their current form. We show how our proposed method is different from the other methods, and that it overcomes the source-sensor location coincidence limitation. Theoretical analysis and experimental data will be used to motivate and justify the pursuit of the proposed approach for localization in a dispersive medium. Additionally, hammer impacts on an instrumented floor section inside an operational building, as well as finite element model simulations, are used to evaluate the performance of the algorithm. It is shown that the algorithm produces promising results providing a foundation for further future development and optimization.

  4. A new local-global approach for classification.

    PubMed

    Peres, R T; Pedreira, C E

    2010-09-01

    In this paper, we propose a new local-global pattern classification scheme that combines supervised and unsupervised approaches, taking advantage of both, local and global environments. We understand as global methods the ones concerned with the aim of constructing a model for the whole problem space using the totality of the available observations. Local methods focus into sub regions of the space, possibly using an appropriately selected subset of the sample. In the proposed method, the sample is first divided in local cells by using a Vector Quantization unsupervised algorithm, the LBG (Linde-Buzo-Gray). In a second stage, the generated assemblage of much easier problems is locally solved with a scheme inspired by Bayes' rule. Four classification methods were implemented for comparison purposes with the proposed scheme: Learning Vector Quantization (LVQ); Feedforward Neural Networks; Support Vector Machine (SVM) and k-Nearest Neighbors. These four methods and the proposed scheme were implemented in eleven datasets, two controlled experiments, plus nine public available datasets from the UCI repository. The proposed method has shown a quite competitive performance when compared to these classical and largely used classifiers. Our method is simple concerning understanding and implementation and is based on very intuitive concepts. Copyright 2010 Elsevier Ltd. All rights reserved.

  5. Image-guided spatial localization of heterogeneous compartments for magnetic resonance

    PubMed Central

    An, Li; Shen, Jun

    2015-01-01

    Purpose: Image-guided localization SPectral Localization Achieved by Sensitivity Heterogeneity (SPLASH) allows rapid measurement of signals from irregularly shaped anatomical compartments without using phase encoding gradients. Here, the authors propose a novel method to address the issue of heterogeneous signal distribution within the localized compartments. Methods: Each compartment was subdivided into multiple subcompartments and their spectra were solved by Tikhonov regularization to enforce smoothness within each compartment. The spectrum of a given compartment was generated by combining the spectra of the components of that compartment. The proposed method was first tested using Monte Carlo simulations and then applied to reconstructing in vivo spectra from irregularly shaped ischemic stroke and normal tissue compartments. Results: Monte Carlo simulations demonstrate that the proposed regularized SPLASH method significantly reduces localization and metabolite quantification errors. In vivo results show that the intracompartment regularization results in ∼40% reduction of error in metabolite quantification. Conclusions: The proposed method significantly reduces localization errors and metabolite quantification errors caused by intracompartment heterogeneous signal distribution. PMID:26328977

  6. Local discretization method for overdamped Brownian motion on a potential with multiple deep wells.

    PubMed

    Nguyen, P T T; Challis, K J; Jack, M W

    2016-11-01

    We present a general method for transforming the continuous diffusion equation describing overdamped Brownian motion on a time-independent potential with multiple deep wells to a discrete master equation. The method is based on an expansion in localized basis states of local metastable potentials that match the full potential in the region of each potential well. Unlike previous basis methods for discretizing Brownian motion on a potential, this approach is valid for periodic potentials with varying multiple deep wells per period and can also be applied to nonperiodic systems. We apply the method to a range of potentials and find that potential wells that are deep compared to five times the thermal energy can be associated with a discrete localized state while shallower wells are better incorporated into the local metastable potentials of neighboring deep potential wells.

  7. Local discretization method for overdamped Brownian motion on a potential with multiple deep wells

    NASA Astrophysics Data System (ADS)

    Nguyen, P. T. T.; Challis, K. J.; Jack, M. W.

    2016-11-01

    We present a general method for transforming the continuous diffusion equation describing overdamped Brownian motion on a time-independent potential with multiple deep wells to a discrete master equation. The method is based on an expansion in localized basis states of local metastable potentials that match the full potential in the region of each potential well. Unlike previous basis methods for discretizing Brownian motion on a potential, this approach is valid for periodic potentials with varying multiple deep wells per period and can also be applied to nonperiodic systems. We apply the method to a range of potentials and find that potential wells that are deep compared to five times the thermal energy can be associated with a discrete localized state while shallower wells are better incorporated into the local metastable potentials of neighboring deep potential wells.

  8. A Localization Method for Underwater Wireless Sensor Networks Based on Mobility Prediction and Particle Swarm Optimization Algorithms

    PubMed Central

    Zhang, Ying; Liang, Jixing; Jiang, Shengming; Chen, Wei

    2016-01-01

    Due to their special environment, Underwater Wireless Sensor Networks (UWSNs) are usually deployed over a large sea area and the nodes are usually floating. This results in a lower beacon node distribution density, a longer time for localization, and more energy consumption. Currently most of the localization algorithms in this field do not pay enough consideration on the mobility of the nodes. In this paper, by analyzing the mobility patterns of water near the seashore, a localization method for UWSNs based on a Mobility Prediction and a Particle Swarm Optimization algorithm (MP-PSO) is proposed. In this method, the range-based PSO algorithm is used to locate the beacon nodes, and their velocities can be calculated. The velocity of an unknown node is calculated by using the spatial correlation of underwater object’s mobility, and then their locations can be predicted. The range-based PSO algorithm may cause considerable energy consumption and its computation complexity is a little bit high, nevertheless the number of beacon nodes is relatively smaller, so the calculation for the large number of unknown nodes is succinct, and this method can obviously decrease the energy consumption and time cost of localizing these mobile nodes. The simulation results indicate that this method has higher localization accuracy and better localization coverage rate compared with some other widely used localization methods in this field. PMID:26861348

  9. Multiscale Methods for Nuclear Reactor Analysis

    NASA Astrophysics Data System (ADS)

    Collins, Benjamin S.

    The ability to accurately predict local pin powers in nuclear reactors is necessary to understand the mechanisms that cause fuel pin failure during steady state and transient operation. In the research presented here, methods are developed to improve the local solution using high order methods with boundary conditions from a low order global solution. Several different core configurations were tested to determine the improvement in the local pin powers compared to the standard techniques, that use diffusion theory and pin power reconstruction (PPR). Two different multiscale methods were developed and analyzed; the post-refinement multiscale method and the embedded multiscale method. The post-refinement multiscale methods use the global solution to determine boundary conditions for the local solution. The local solution is solved using either a fixed boundary source or an albedo boundary condition; this solution is "post-refinement" and thus has no impact on the global solution. The embedded multiscale method allows the local solver to change the global solution to provide an improved global and local solution. The post-refinement multiscale method is assessed using three core designs. When the local solution has more energy groups, the fixed source method has some difficulties near the interface: however the albedo method works well for all cases. In order to remedy the issue with boundary condition errors for the fixed source method, a buffer region is used to act as a filter, which decreases the sensitivity of the solution to the boundary condition. Both the albedo and fixed source methods benefit from the use of a buffer region. Unlike the post-refinement method, the embedded multiscale method alters the global solution. The ability to change the global solution allows for refinement in areas where the errors in the few group nodal diffusion are typically large. The embedded method is shown to improve the global solution when it is applied to a MOX/LEU assembly interface, the fuel/reflector interface, and assemblies where control rods are inserted. The embedded method also allows for multiple solution levels to be applied in a single calculation. The addition of intermediate levels to the solution improves the accuracy of the method. Both multiscale methods considered here have benefits and drawbacks, but both can provide improvements over the current PPR methodology.

  10. Concepts in local treatment of extensive paediatric burns.

    PubMed

    Ungureanu, M

    2014-06-15

    There is a wide variety of local therapeutical methods for extensive burns. This article aims to be a general overview of the most common methods used in the local treatment for extensive burns, both in our clinic and globally. Clinical examples are shown from our clinic; cases of the last 8 years. None of the less there is no such thing as the "perfect method of treatment" but a thin balance between the clinical experience of plastic surgeons, every case particularities and specified characteristics, meaning advantages, disadvantages and limited indications of local topics or methods of skin covering.

  11. Finger vein recognition using local line binary pattern.

    PubMed

    Rosdi, Bakhtiar Affendi; Shing, Chai Wuh; Suandi, Shahrel Azmin

    2011-01-01

    In this paper, a personal verification method using finger vein is presented. Finger vein can be considered more secured compared to other hands based biometric traits such as fingerprint and palm print because the features are inside the human body. In the proposed method, a new texture descriptor called local line binary pattern (LLBP) is utilized as feature extraction technique. The neighbourhood shape in LLBP is a straight line, unlike in local binary pattern (LBP) which is a square shape. Experimental results show that the proposed method using LLBP has better performance than the previous methods using LBP and local derivative pattern (LDP).

  12. Concepts in local treatment of extensive paediatric burns

    PubMed Central

    Ungureanu, M

    2014-01-01

    Abstract There is a wide variety of local therapeutical methods for extensive burns. This article aims to be a general overview of the most common methods used in the local treatment for extensive burns, both in our clinic and globally. Clinical examples are shown from our clinic; cases of the last 8 years. None of the less there is no such thing as the "perfect method of treatment" but a thin balance between the clinical experience of plastic surgeons, every case particularities and specified characteristics, meaning advantages, disadvantages and limited indications of local topics or methods of skin covering. PMID:25408723

  13. Global/local methods for probabilistic structural analysis

    NASA Technical Reports Server (NTRS)

    Millwater, H. R.; Wu, Y.-T.

    1993-01-01

    A probabilistic global/local method is proposed to reduce the computational requirements of probabilistic structural analysis. A coarser global model is used for most of the computations with a local more refined model used only at key probabilistic conditions. The global model is used to establish the cumulative distribution function (cdf) and the Most Probable Point (MPP). The local model then uses the predicted MPP to adjust the cdf value. The global/local method is used within the advanced mean value probabilistic algorithm. The local model can be more refined with respect to the g1obal model in terms of finer mesh, smaller time step, tighter tolerances, etc. and can be used with linear or nonlinear models. The basis for this approach is described in terms of the correlation between the global and local models which can be estimated from the global and local MPPs. A numerical example is presented using the NESSUS probabilistic structural analysis program with the finite element method used for the structural modeling. The results clearly indicate a significant computer savings with minimal loss in accuracy.

  14. Global/local methods for probabilistic structural analysis

    NASA Astrophysics Data System (ADS)

    Millwater, H. R.; Wu, Y.-T.

    1993-04-01

    A probabilistic global/local method is proposed to reduce the computational requirements of probabilistic structural analysis. A coarser global model is used for most of the computations with a local more refined model used only at key probabilistic conditions. The global model is used to establish the cumulative distribution function (cdf) and the Most Probable Point (MPP). The local model then uses the predicted MPP to adjust the cdf value. The global/local method is used within the advanced mean value probabilistic algorithm. The local model can be more refined with respect to the g1obal model in terms of finer mesh, smaller time step, tighter tolerances, etc. and can be used with linear or nonlinear models. The basis for this approach is described in terms of the correlation between the global and local models which can be estimated from the global and local MPPs. A numerical example is presented using the NESSUS probabilistic structural analysis program with the finite element method used for the structural modeling. The results clearly indicate a significant computer savings with minimal loss in accuracy.

  15. Local Discontinuous Galerkin Methods for Partial Differential Equations with Higher Order Derivatives

    NASA Technical Reports Server (NTRS)

    Yan, Jue; Shu, Chi-Wang; Bushnell, Dennis M. (Technical Monitor)

    2002-01-01

    In this paper we review the existing and develop new continuous Galerkin methods for solving time dependent partial differential equations with higher order derivatives in one and multiple space dimensions. We review local discontinuous Galerkin methods for convection diffusion equations involving second derivatives and for KdV type equations involving third derivatives. We then develop new local discontinuous Galerkin methods for the time dependent bi-harmonic type equations involving fourth derivatives, and partial differential equations involving fifth derivatives. For these new methods we present correct interface numerical fluxes and prove L(exp 2) stability for general nonlinear problems. Preliminary numerical examples are shown to illustrate these methods. Finally, we present new results on a post-processing technique, originally designed for methods with good negative-order error estimates, on the local discontinuous Galerkin methods applied to equations with higher derivatives. Numerical experiments show that this technique works as well for the new higher derivative cases, in effectively doubling the rate of convergence with negligible additional computational cost, for linear as well as some nonlinear problems, with a local uniform mesh.

  16. Improving IMES Localization Accuracy by Integrating Dead Reckoning Information

    PubMed Central

    Fujii, Kenjiro; Arie, Hiroaki; Wang, Wei; Kaneko, Yuto; Sakamoto, Yoshihiro; Schmitz, Alexander; Sugano, Shigeki

    2016-01-01

    Indoor positioning remains an open problem, because it is difficult to achieve satisfactory accuracy within an indoor environment using current radio-based localization technology. In this study, we investigate the use of Indoor Messaging System (IMES) radio for high-accuracy indoor positioning. A hybrid positioning method combining IMES radio strength information and pedestrian dead reckoning information is proposed in order to improve IMES localization accuracy. For understanding the carrier noise ratio versus distance relation for IMES radio, the signal propagation of IMES radio is modeled and identified. Then, trilateration and extended Kalman filtering methods using the radio propagation model are developed for position estimation. These methods are evaluated through robot localization and pedestrian localization experiments. The experimental results show that the proposed hybrid positioning method achieved average estimation errors of 217 and 1846 mm in robot localization and pedestrian localization, respectively. In addition, in order to examine the reason for the positioning accuracy of pedestrian localization being much lower than that of robot localization, the influence of the human body on the radio propagation is experimentally evaluated. The result suggests that the influence of the human body can be modeled. PMID:26828492

  17. Local Intrinsic Dimension Estimation by Generalized Linear Modeling.

    PubMed

    Hino, Hideitsu; Fujiki, Jun; Akaho, Shotaro; Murata, Noboru

    2017-07-01

    We propose a method for intrinsic dimension estimation. By fitting the power of distance from an inspection point and the number of samples included inside a ball with a radius equal to the distance, to a regression model, we estimate the goodness of fit. Then, by using the maximum likelihood method, we estimate the local intrinsic dimension around the inspection point. The proposed method is shown to be comparable to conventional methods in global intrinsic dimension estimation experiments. Furthermore, we experimentally show that the proposed method outperforms a conventional local dimension estimation method.

  18. Brain tumor segmentation based on local independent projection-based classification.

    PubMed

    Huang, Meiyan; Yang, Wei; Wu, Yao; Jiang, Jun; Chen, Wufan; Feng, Qianjin

    2014-10-01

    Brain tumor segmentation is an important procedure for early tumor diagnosis and radiotherapy planning. Although numerous brain tumor segmentation methods have been presented, enhancing tumor segmentation methods is still challenging because brain tumor MRI images exhibit complex characteristics, such as high diversity in tumor appearance and ambiguous tumor boundaries. To address this problem, we propose a novel automatic tumor segmentation method for MRI images. This method treats tumor segmentation as a classification problem. Additionally, the local independent projection-based classification (LIPC) method is used to classify each voxel into different classes. A novel classification framework is derived by introducing the local independent projection into the classical classification model. Locality is important in the calculation of local independent projections for LIPC. Locality is also considered in determining whether local anchor embedding is more applicable in solving linear projection weights compared with other coding methods. Moreover, LIPC considers the data distribution of different classes by learning a softmax regression model, which can further improve classification performance. In this study, 80 brain tumor MRI images with ground truth data are used as training data and 40 images without ground truth data are used as testing data. The segmentation results of testing data are evaluated by an online evaluation tool. The average dice similarities of the proposed method for segmenting complete tumor, tumor core, and contrast-enhancing tumor on real patient data are 0.84, 0.685, and 0.585, respectively. These results are comparable to other state-of-the-art methods.

  19. Localized diabatization applied to excitons in molecular crystals

    NASA Astrophysics Data System (ADS)

    Jin, Zuxin; Subotnik, Joseph E.

    2017-06-01

    Traditional ab initio electronic structure calculations of periodic systems yield delocalized eigenstates that should be understood as adiabatic states. For example, excitons are bands of extended states which superimpose localized excitations on every lattice site. However, in general, in order to study the effects of nuclear motion on exciton transport, it is standard to work with a localized description of excitons, especially in a hopping regime; even in a band regime, a localized description can be helpful. To extract localized excitons from a band requires essentially a diabatization procedure. In this paper, three distinct methods are proposed for such localized diabatization: (i) a simple projection method, (ii) a more general Pipek-Mezey localization scheme, and (iii) a variant of Boys diabatization. Approaches (i) and (ii) require localized, single-particle Wannier orbitals, while approach (iii) has no such dependence. These methods should be very useful for studying energy transfer through solids with ab initio calculations.

  20. Anchor-Free Localization Method for Mobile Targets in Coal Mine Wireless Sensor Networks

    PubMed Central

    Pei, Zhongmin; Deng, Zhidong; Xu, Shuo; Xu, Xiao

    2009-01-01

    Severe natural conditions and complex terrain make it difficult to apply precise localization in underground mines. In this paper, an anchor-free localization method for mobile targets is proposed based on non-metric multi-dimensional scaling (Multi-dimensional Scaling: MDS) and rank sequence. Firstly, a coal mine wireless sensor network is constructed in underground mines based on the ZigBee technology. Then a non-metric MDS algorithm is imported to estimate the reference nodes’ location. Finally, an improved sequence-based localization algorithm is presented to complete precise localization for mobile targets. The proposed method is tested through simulations with 100 nodes, outdoor experiments with 15 ZigBee physical nodes, and the experiments in the mine gas explosion laboratory with 12 ZigBee nodes. Experimental results show that our method has better localization accuracy and is more robust in underground mines. PMID:22574048

  1. Anchor-free localization method for mobile targets in coal mine wireless sensor networks.

    PubMed

    Pei, Zhongmin; Deng, Zhidong; Xu, Shuo; Xu, Xiao

    2009-01-01

    Severe natural conditions and complex terrain make it difficult to apply precise localization in underground mines. In this paper, an anchor-free localization method for mobile targets is proposed based on non-metric multi-dimensional scaling (Multi-dimensional Scaling: MDS) and rank sequence. Firstly, a coal mine wireless sensor network is constructed in underground mines based on the ZigBee technology. Then a non-metric MDS algorithm is imported to estimate the reference nodes' location. Finally, an improved sequence-based localization algorithm is presented to complete precise localization for mobile targets. The proposed method is tested through simulations with 100 nodes, outdoor experiments with 15 ZigBee physical nodes, and the experiments in the mine gas explosion laboratory with 12 ZigBee nodes. Experimental results show that our method has better localization accuracy and is more robust in underground mines.

  2. Localization of a variational particle smoother

    NASA Astrophysics Data System (ADS)

    Morzfeld, M.; Hodyss, D.; Poterjoy, J.

    2017-12-01

    Given the success of 4D-variational methods (4D-Var) in numerical weather prediction,and recent efforts to merge ensemble Kalman filters with 4D-Var,we consider a method to merge particle methods and 4D-Var.This leads us to revisit variational particle smoothers (varPS).We study the collapse of varPS in high-dimensional problemsand show how it can be prevented by weight-localization.We test varPS on the Lorenz'96 model of dimensionsn=40, n=400, and n=2000.In our numerical experiments, weight localization prevents the collapse of the varPS,and we note that the varPS yields results comparable to ensemble formulations of 4D-variational methods,while it outperforms EnKF with tuned localization and inflation,and the localized standard particle filter.Additional numerical experiments suggest that using localized weights in varPS may not yield significant advantages over unweighted or linearizedsolutions in near-Gaussian problems.

  3. A comparison of locally adaptive multigrid methods: LDC, FAC and FIC

    NASA Technical Reports Server (NTRS)

    Khadra, Khodor; Angot, Philippe; Caltagirone, Jean-Paul

    1993-01-01

    This study is devoted to a comparative analysis of three 'Adaptive ZOOM' (ZOom Overlapping Multi-level) methods based on similar concepts of hierarchical multigrid local refinement: LDC (Local Defect Correction), FAC (Fast Adaptive Composite), and FIC (Flux Interface Correction)--which we proposed recently. These methods are tested on two examples of a bidimensional elliptic problem. We compare, for V-cycle procedures, the asymptotic evolution of the global error evaluated by discrete norms, the corresponding local errors, and the convergence rates of these algorithms.

  4. Learning Rotation-Invariant Local Binary Descriptor.

    PubMed

    Duan, Yueqi; Lu, Jiwen; Feng, Jianjiang; Zhou, Jie

    2017-08-01

    In this paper, we propose a rotation-invariant local binary descriptor (RI-LBD) learning method for visual recognition. Compared with hand-crafted local binary descriptors, such as local binary pattern and its variants, which require strong prior knowledge, local binary feature learning methods are more efficient and data-adaptive. Unlike existing learning-based local binary descriptors, such as compact binary face descriptor and simultaneous local binary feature learning and encoding, which are susceptible to rotations, our RI-LBD first categorizes each local patch into a rotational binary pattern (RBP), and then jointly learns the orientation for each pattern and the projection matrix to obtain RI-LBDs. As all the rotation variants of a patch belong to the same RBP, they are rotated into the same orientation and projected into the same binary descriptor. Then, we construct a codebook by a clustering method on the learned binary codes, and obtain a histogram feature for each image as the final representation. In order to exploit higher order statistical information, we extend our RI-LBD to the triple rotation-invariant co-occurrence local binary descriptor (TRICo-LBD) learning method, which learns a triple co-occurrence binary code for each local patch. Extensive experimental results on four different visual recognition tasks, including image patch matching, texture classification, face recognition, and scene classification, show that our RI-LBD and TRICo-LBD outperform most existing local descriptors.

  5. The interactive electrode localization utility: software for automatic sorting and labeling of intracranial subdural electrodes

    PubMed Central

    Tang, Wei; Peled, Noam; Vallejo, Deborah I.; Borzello, Mia; Dougherty, Darin D.; Eskandar, Emad N.; Widge, Alik S.; Cash, Sydney S.; Stufflebeam, Steven M.

    2018-01-01

    Purpose Existing methods for sorting, labeling, registering, and across-subject localization of electrodes in intracranial encephalography (iEEG) may involve laborious work requiring manual inspection of radiological images. Methods We describe a new open-source software package, the interactive electrode localization utility which presents a full pipeline for the registration, localization, and labeling of iEEG electrodes from CT and MR images. In addition, we describe a method to automatically sort and label electrodes from subdural grids of known geometry. Results We validated our software against manual inspection methods in twelve subjects undergoing iEEG for medically intractable epilepsy. Our algorithm for sorting and labeling performed correct identification on 96% of the electrodes. Conclusions The sorting and labeling methods we describe offer nearly perfect performance and the software package we have distributed may simplify the process of registering, sorting, labeling, and localizing subdural iEEG grid electrodes by manual inspection. PMID:27915398

  6. Local Discontinuous Galerkin Methods for the Cahn-Hilliard Type Equations

    DTIC Science & Technology

    2007-01-01

    Kuramoto-Sivashinsky equations , the Ito-type coupled KdV equa- tions, the Kadomtsev - Petviashvili equation , and the Zakharov-Kuznetsov equation . A common...Local discontinuous Galerkin methods for the Cahn-Hilliard type equations Yinhua Xia∗, Yan Xu† and Chi-Wang Shu ‡ Abstract In this paper we develop...local discontinuous Galerkin (LDG) methods for the fourth-order nonlinear Cahn-Hilliard equation and system. The energy stability of the LDG methods is

  7. Localization of rainfall and determination its intensity in the lower layers of the troposphere from the measurements of local RF transmitter characteristics

    NASA Astrophysics Data System (ADS)

    Podhorský, Dušan; Fabo, Peter

    2016-12-01

    The article deals with a method of acquiring the temporal and spatial distribution of local precipitation from measurement of performance characteristics of local sources of high frequency electromagnetic radiation in the 1-3GHz frequency range in the lower layers of the troposphere up to 100 m. The method was experimentally proven by monitoring the GSM G2 base stations of cell phone providers in the frequency range of 920-960MHz using methods of frequential and spatial diversity reception. Modification of the SART method for localization of precipitation was also proposed. The achieved results allow us to obtain the timeframe of the intensity of local precipitation in the observed area with a temporal resolution of 10 sec. A spatial accuracy of 100m in localization of precipitation is expected, after a network of receivers is built. The acquired data can be used as one of the inputs for meteorological forecasting models, in agriculture, hydrology as a supplementary method to ombrograph stations and measurements for the weather radar network, in transportation as part of a warning system and in many other areas.

  8. Method for localizing heating in tumor tissue

    DOEpatents

    Doss, James D.; McCabe, Charles W.

    1977-04-12

    A method for a localized tissue heating of tumors is disclosed. Localized radio frequency current fields are produced with specific electrode configurations. Several electrode configurations are disclosed, enabling variations in electrical and thermal properties of tissues to be exploited.

  9. The detection of local irreversibility in time series based on segmentation

    NASA Astrophysics Data System (ADS)

    Teng, Yue; Shang, Pengjian

    2018-06-01

    We propose a strategy for the detection of local irreversibility in stationary time series based on multiple scale. The detection is beneficial to evaluate the displacement of irreversibility toward local skewness. By means of this method, we can availably discuss the local irreversible fluctuations of time series as the scale changes. The method was applied to simulated nonlinear signals generated by the ARFIMA process and logistic map to show how the irreversibility functions react to the increasing of the multiple scale. The method was applied also to series of financial markets i.e., American, Chinese and European markets. The local irreversibility for different markets demonstrate distinct characteristics. Simulations and real data support the need of exploring local irreversibility.

  10. Local Laplacian Coding From Theoretical Analysis of Local Coding Schemes for Locally Linear Classification.

    PubMed

    Pang, Junbiao; Qin, Lei; Zhang, Chunjie; Zhang, Weigang; Huang, Qingming; Yin, Baocai

    2015-12-01

    Local coordinate coding (LCC) is a framework to approximate a Lipschitz smooth function by combining linear functions into a nonlinear one. For locally linear classification, LCC requires a coding scheme that heavily determines the nonlinear approximation ability, posing two main challenges: 1) the locality making faraway anchors have smaller influences on current data and 2) the flexibility balancing well between the reconstruction of current data and the locality. In this paper, we address the problem from the theoretical analysis of the simplest local coding schemes, i.e., local Gaussian coding and local student coding, and propose local Laplacian coding (LPC) to achieve the locality and the flexibility. We apply LPC into locally linear classifiers to solve diverse classification tasks. The comparable or exceeded performances of state-of-the-art methods demonstrate the effectiveness of the proposed method.

  11. Remote sensing image segmentation using local sparse structure constrained latent low rank representation

    NASA Astrophysics Data System (ADS)

    Tian, Shu; Zhang, Ye; Yan, Yimin; Su, Nan; Zhang, Junping

    2016-09-01

    Latent low-rank representation (LatLRR) has been attached considerable attention in the field of remote sensing image segmentation, due to its effectiveness in exploring the multiple subspace structures of data. However, the increasingly heterogeneous texture information in the high spatial resolution remote sensing images, leads to more severe interference of pixels in local neighborhood, and the LatLRR fails to capture the local complex structure information. Therefore, we present a local sparse structure constrainted latent low-rank representation (LSSLatLRR) segmentation method, which explicitly imposes the local sparse structure constraint on LatLRR to capture the intrinsic local structure in manifold structure feature subspaces. The whole segmentation framework can be viewed as two stages in cascade. In the first stage, we use the local histogram transform to extract the texture local histogram features (LHOG) at each pixel, which can efficiently capture the complex and micro-texture pattern. In the second stage, a local sparse structure (LSS) formulation is established on LHOG, which aims to preserve the local intrinsic structure and enhance the relationship between pixels having similar local characteristics. Meanwhile, by integrating the LSS and the LatLRR, we can efficiently capture the local sparse and low-rank structure in the mixture of feature subspace, and we adopt the subspace segmentation method to improve the segmentation accuracy. Experimental results on the remote sensing images with different spatial resolution show that, compared with three state-of-the-art image segmentation methods, the proposed method achieves more accurate segmentation results.

  12. Finger Vein Recognition Using Local Line Binary Pattern

    PubMed Central

    Rosdi, Bakhtiar Affendi; Shing, Chai Wuh; Suandi, Shahrel Azmin

    2011-01-01

    In this paper, a personal verification method using finger vein is presented. Finger vein can be considered more secured compared to other hands based biometric traits such as fingerprint and palm print because the features are inside the human body. In the proposed method, a new texture descriptor called local line binary pattern (LLBP) is utilized as feature extraction technique. The neighbourhood shape in LLBP is a straight line, unlike in local binary pattern (LBP) which is a square shape. Experimental results show that the proposed method using LLBP has better performance than the previous methods using LBP and local derivative pattern (LDP). PMID:22247670

  13. Evaluation and comparison of 3D intervertebral disc localization and segmentation methods for 3D T2 MR data: A grand challenge.

    PubMed

    Zheng, Guoyan; Chu, Chengwen; Belavý, Daniel L; Ibragimov, Bulat; Korez, Robert; Vrtovec, Tomaž; Hutt, Hugo; Everson, Richard; Meakin, Judith; Andrade, Isabel Lŏpez; Glocker, Ben; Chen, Hao; Dou, Qi; Heng, Pheng-Ann; Wang, Chunliang; Forsberg, Daniel; Neubert, Aleš; Fripp, Jurgen; Urschler, Martin; Stern, Darko; Wimmer, Maria; Novikov, Alexey A; Cheng, Hui; Armbrecht, Gabriele; Felsenberg, Dieter; Li, Shuo

    2017-01-01

    The evaluation of changes in Intervertebral Discs (IVDs) with 3D Magnetic Resonance (MR) Imaging (MRI) can be of interest for many clinical applications. This paper presents the evaluation of both IVD localization and IVD segmentation methods submitted to the Automatic 3D MRI IVD Localization and Segmentation challenge, held at the 2015 International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI2015) with an on-site competition. With the construction of a manually annotated reference data set composed of 25 3D T2-weighted MR images acquired from two different studies and the establishment of a standard validation framework, quantitative evaluation was performed to compare the results of methods submitted to the challenge. Experimental results show that overall the best localization method achieves a mean localization distance of 0.8 mm and the best segmentation method achieves a mean Dice of 91.8%, a mean average absolute distance of 1.1 mm and a mean Hausdorff distance of 4.3 mm, respectively. The strengths and drawbacks of each method are discussed, which provides insights into the performance of different IVD localization and segmentation methods. Copyright © 2016 Elsevier B.V. All rights reserved.

  14. Improving performances of suboptimal greedy iterative biclustering heuristics via localization.

    PubMed

    Erten, Cesim; Sözdinler, Melih

    2010-10-15

    Biclustering gene expression data is the problem of extracting submatrices of genes and conditions exhibiting significant correlation across both the rows and the columns of a data matrix of expression values. Even the simplest versions of the problem are computationally hard. Most of the proposed solutions therefore employ greedy iterative heuristics that locally optimize a suitably assigned scoring function. We provide a fast and simple pre-processing algorithm called localization that reorders the rows and columns of the input data matrix in such a way as to group correlated entries in small local neighborhoods within the matrix. The proposed localization algorithm takes its roots from effective use of graph-theoretical methods applied to problems exhibiting a similar structure to that of biclustering. In order to evaluate the effectivenesss of the localization pre-processing algorithm, we focus on three representative greedy iterative heuristic methods. We show how the localization pre-processing can be incorporated into each representative algorithm to improve biclustering performance. Furthermore, we propose a simple biclustering algorithm, Random Extraction After Localization (REAL) that randomly extracts submatrices from the localization pre-processed data matrix, eliminates those with low similarity scores, and provides the rest as correlated structures representing biclusters. We compare the proposed localization pre-processing with another pre-processing alternative, non-negative matrix factorization. We show that our fast and simple localization procedure provides similar or even better results than the computationally heavy matrix factorization pre-processing with regards to H-value tests. We next demonstrate that the performances of the three representative greedy iterative heuristic methods improve with localization pre-processing when biological correlations in the form of functional enrichment and PPI verification constitute the main performance criteria. The fact that the random extraction method based on localization REAL performs better than the representative greedy heuristic methods under same criteria also confirms the effectiveness of the suggested pre-processing method. Supplementary material including code implementations in LEDA C++ library, experimental data, and the results are available at http://code.google.com/p/biclustering/ cesim@khas.edu.tr; melihsozdinler@boun.edu.tr Supplementary data are available at Bioinformatics online.

  15. Problems d'elaboration d'une methode locale: la methode "Paris-Khartoum" (Problems in Implementing a Local Method: the Paris-Khartoum Method)

    ERIC Educational Resources Information Center

    Penhoat, Loick; Sakow, Kostia

    1978-01-01

    A description of the development and implementation of a method introduced in the Sudan that attempts to relate to Sudanese culture and to motivate students. The relationship between language teaching methods and the total educational system is discussed. (AMH)

  16. Finding the Genomic Basis of Local Adaptation: Pitfalls, Practical Solutions, and Future Directions.

    PubMed

    Hoban, Sean; Kelley, Joanna L; Lotterhos, Katie E; Antolin, Michael F; Bradburd, Gideon; Lowry, David B; Poss, Mary L; Reed, Laura K; Storfer, Andrew; Whitlock, Michael C

    2016-10-01

    Uncovering the genetic and evolutionary basis of local adaptation is a major focus of evolutionary biology. The recent development of cost-effective methods for obtaining high-quality genome-scale data makes it possible to identify some of the loci responsible for adaptive differences among populations. Two basic approaches for identifying putatively locally adaptive loci have been developed and are broadly used: one that identifies loci with unusually high genetic differentiation among populations (differentiation outlier methods) and one that searches for correlations between local population allele frequencies and local environments (genetic-environment association methods). Here, we review the promises and challenges of these genome scan methods, including correcting for the confounding influence of a species' demographic history, biases caused by missing aspects of the genome, matching scales of environmental data with population structure, and other statistical considerations. In each case, we make suggestions for best practices for maximizing the accuracy and efficiency of genome scans to detect the underlying genetic basis of local adaptation. With attention to their current limitations, genome scan methods can be an important tool in finding the genetic basis of adaptive evolutionary change.

  17. Local polynomial chaos expansion for linear differential equations with high dimensional random inputs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chen, Yi; Jakeman, John; Gittelson, Claude

    2015-01-08

    In this paper we present a localized polynomial chaos expansion for partial differential equations (PDE) with random inputs. In particular, we focus on time independent linear stochastic problems with high dimensional random inputs, where the traditional polynomial chaos methods, and most of the existing methods, incur prohibitively high simulation cost. Furthermore, the local polynomial chaos method employs a domain decomposition technique to approximate the stochastic solution locally. In each subdomain, a subdomain problem is solved independently and, more importantly, in a much lower dimensional random space. In a postprocesing stage, accurate samples of the original stochastic problems are obtained frommore » the samples of the local solutions by enforcing the correct stochastic structure of the random inputs and the coupling conditions at the interfaces of the subdomains. Overall, the method is able to solve stochastic PDEs in very large dimensions by solving a collection of low dimensional local problems and can be highly efficient. In our paper we present the general mathematical framework of the methodology and use numerical examples to demonstrate the properties of the method.« less

  18. Distributed State Estimation Using a Modified Partitioned Moving Horizon Strategy for Power Systems.

    PubMed

    Chen, Tengpeng; Foo, Yi Shyh Eddy; Ling, K V; Chen, Xuebing

    2017-10-11

    In this paper, a distributed state estimation method based on moving horizon estimation (MHE) is proposed for the large-scale power system state estimation. The proposed method partitions the power systems into several local areas with non-overlapping states. Unlike the centralized approach where all measurements are sent to a processing center, the proposed method distributes the state estimation task to the local processing centers where local measurements are collected. Inspired by the partitioned moving horizon estimation (PMHE) algorithm, each local area solves a smaller optimization problem to estimate its own local states by using local measurements and estimated results from its neighboring areas. In contrast with PMHE, the error from the process model is ignored in our method. The proposed modified PMHE (mPMHE) approach can also take constraints on states into account during the optimization process such that the influence of the outliers can be further mitigated. Simulation results on the IEEE 14-bus and 118-bus systems verify that our method achieves comparable state estimation accuracy but with a significant reduction in the overall computation load.

  19. Cohesive energy and structural parameters of binary oxides of groups IIA and IIIB from diffusion quantum Monte Carlo

    DOE PAGES

    Santana, Juan A.; Krogel, Jaron T.; Kent, Paul R. C.; ...

    2016-05-03

    We have applied the diffusion quantum Monte Carlo (DMC) method to calculate the cohesive energy and the structural parameters of the binary oxides CaO, SrO, BaO, Sc 2O 3, Y 2O 3 and La 2O 3. The aim of our calculations is to systematically quantify the accuracy of the DMC method to study this type of metal oxides. The DMC results were compared with local and semi-local Density Functional Theory (DFT) approximations as well as with experimental measurements. The DMC method yields cohesive energies for these oxides with a mean absolute deviation from experimental measurements of 0.18(2) eV, while withmore » local and semi-local DFT approximations the deviation is 3.06 and 0.94 eV, respectively. For lattice constants, the mean absolute deviation in DMC, local and semi-local DFT approximations, are 0.017(1), 0.07 and 0.05 , respectively. In conclusion, DMC is highly accurate method, outperforming the local and semi-local DFT approximations in describing the cohesive energies and structural parameters of these binary oxides.« less

  20. Potential energy surface fitting by a statistically localized, permutationally invariant, local interpolating moving least squares method for the many-body potential: Method and application to N{sub 4}

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bender, Jason D.; Doraiswamy, Sriram; Candler, Graham V., E-mail: truhlar@umn.edu, E-mail: candler@aem.umn.edu

    2014-02-07

    Fitting potential energy surfaces to analytic forms is an important first step for efficient molecular dynamics simulations. Here, we present an improved version of the local interpolating moving least squares method (L-IMLS) for such fitting. Our method has three key improvements. First, pairwise interactions are modeled separately from many-body interactions. Second, permutational invariance is incorporated in the basis functions, using permutationally invariant polynomials in Morse variables, and in the weight functions. Third, computational cost is reduced by statistical localization, in which we statistically correlate the cutoff radius with data point density. We motivate our discussion in this paper with amore » review of global and local least-squares-based fitting methods in one dimension. Then, we develop our method in six dimensions, and we note that it allows the analytic evaluation of gradients, a feature that is important for molecular dynamics. The approach, which we call statistically localized, permutationally invariant, local interpolating moving least squares fitting of the many-body potential (SL-PI-L-IMLS-MP, or, more simply, L-IMLS-G2), is used to fit a potential energy surface to an electronic structure dataset for N{sub 4}. We discuss its performance on the dataset and give directions for further research, including applications to trajectory calculations.« less

  1. Protein subcellular localization prediction using artificial intelligence technology.

    PubMed

    Nair, Rajesh; Rost, Burkhard

    2008-01-01

    Proteins perform many important tasks in living organisms, such as catalysis of biochemical reactions, transport of nutrients, and recognition and transmission of signals. The plethora of aspects of the role of any particular protein is referred to as its "function." One aspect of protein function that has been the target of intensive research by computational biologists is its subcellular localization. Proteins must be localized in the same subcellular compartment to cooperate toward a common physiological function. Aberrant subcellular localization of proteins can result in several diseases, including kidney stones, cancer, and Alzheimer's disease. To date, sequence homology remains the most widely used method for inferring the function of a protein. However, the application of advanced artificial intelligence (AI)-based techniques in recent years has resulted in significant improvements in our ability to predict the subcellular localization of a protein. The prediction accuracy has risen steadily over the years, in large part due to the application of AI-based methods such as hidden Markov models (HMMs), neural networks (NNs), and support vector machines (SVMs), although the availability of larger experimental datasets has also played a role. Automatic methods that mine textual information from the biological literature and molecular biology databases have considerably sped up the process of annotation for proteins for which some information regarding function is available in the literature. State-of-the-art methods based on NNs and HMMs can predict the presence of N-terminal sorting signals extremely accurately. Ab initio methods that predict subcellular localization for any protein sequence using only the native amino acid sequence and features predicted from the native sequence have shown the most remarkable improvements. The prediction accuracy of these methods has increased by over 30% in the past decade. The accuracy of these methods is now on par with high-throughput methods for predicting localization, and they are beginning to play an important role in directing experimental research. In this chapter, we review some of the most important methods for the prediction of subcellular localization.

  2. Well-conditioning global-local analysis using stable generalized/extended finite element method for linear elastic fracture mechanics

    NASA Astrophysics Data System (ADS)

    Malekan, Mohammad; Barros, Felicio Bruzzi

    2016-11-01

    Using the locally-enriched strategy to enrich a small/local part of the problem by generalized/extended finite element method (G/XFEM) leads to non-optimal convergence rate and ill-conditioning system of equations due to presence of blending elements. The local enrichment can be chosen from polynomial, singular, branch or numerical types. The so-called stable version of G/XFEM method provides a well-conditioning approach when only singular functions are used in the blending elements. This paper combines numeric enrichment functions obtained from global-local G/XFEM method with the polynomial enrichment along with a well-conditioning approach, stable G/XFEM, in order to show the robustness and effectiveness of the approach. In global-local G/XFEM, the enrichment functions are constructed numerically from the solution of a local problem. Furthermore, several enrichment strategies are adopted along with the global-local enrichment. The results obtained with these enrichments strategies are discussed in detail, considering convergence rate in strain energy, growth rate of condition number, and computational processing. Numerical experiments show that using geometrical enrichment along with stable G/XFEM for global-local strategy improves the convergence rate and the conditioning of the problem. In addition, results shows that using polynomial enrichment for global problem simultaneously with global-local enrichments lead to ill-conditioned system matrices and bad convergence rate.

  3. Scan statistics with local vote for target detection in distributed system

    NASA Astrophysics Data System (ADS)

    Luo, Junhai; Wu, Qi

    2017-12-01

    Target detection has occupied a pivotal position in distributed system. Scan statistics, as one of the most efficient detection methods, has been applied to a variety of anomaly detection problems and significantly improves the probability of detection. However, scan statistics cannot achieve the expected performance when the noise intensity is strong, or the signal emitted by the target is weak. The local vote algorithm can also achieve higher target detection rate. After the local vote, the counting rule is always adopted for decision fusion. The counting rule does not use the information about the contiguity of sensors but takes all sensors' data into consideration, which makes the result undesirable. In this paper, we propose a scan statistics with local vote (SSLV) method. This method combines scan statistics with local vote decision. Before scan statistics, each sensor executes local vote decision according to the data of its neighbors and its own. By combining the advantages of both, our method can obtain higher detection rate in low signal-to-noise ratio environment than the scan statistics. After the local vote decision, the distribution of sensors which have detected the target becomes more intensive. To make full use of local vote decision, we introduce a variable-step-parameter for the SSLV. It significantly shortens the scan period especially when the target is absent. Analysis and simulations are presented to demonstrate the performance of our method.

  4. Real-Time Multi-Target Localization from Unmanned Aerial Vehicles

    PubMed Central

    Wang, Xuan; Liu, Jinghong; Zhou, Qianfei

    2016-01-01

    In order to improve the reconnaissance efficiency of unmanned aerial vehicle (UAV) electro-optical stabilized imaging systems, a real-time multi-target localization scheme based on an UAV electro-optical stabilized imaging system is proposed. First, a target location model is studied. Then, the geodetic coordinates of multi-targets are calculated using the homogeneous coordinate transformation. On the basis of this, two methods which can improve the accuracy of the multi-target localization are proposed: (1) the real-time zoom lens distortion correction method; (2) a recursive least squares (RLS) filtering method based on UAV dead reckoning. The multi-target localization error model is established using Monte Carlo theory. In an actual flight, the UAV flight altitude is 1140 m. The multi-target localization results are within the range of allowable error. After we use a lens distortion correction method in a single image, the circular error probability (CEP) of the multi-target localization is reduced by 7%, and 50 targets can be located at the same time. The RLS algorithm can adaptively estimate the location data based on multiple images. Compared with multi-target localization based on a single image, CEP of the multi-target localization using RLS is reduced by 25%. The proposed method can be implemented on a small circuit board to operate in real time. This research is expected to significantly benefit small UAVs which need multi-target geo-location functions. PMID:28029145

  5. Real-Time Multi-Target Localization from Unmanned Aerial Vehicles.

    PubMed

    Wang, Xuan; Liu, Jinghong; Zhou, Qianfei

    2016-12-25

    In order to improve the reconnaissance efficiency of unmanned aerial vehicle (UAV) electro-optical stabilized imaging systems, a real-time multi-target localization scheme based on an UAV electro-optical stabilized imaging system is proposed. First, a target location model is studied. Then, the geodetic coordinates of multi-targets are calculated using the homogeneous coordinate transformation. On the basis of this, two methods which can improve the accuracy of the multi-target localization are proposed: (1) the real-time zoom lens distortion correction method; (2) a recursive least squares (RLS) filtering method based on UAV dead reckoning. The multi-target localization error model is established using Monte Carlo theory. In an actual flight, the UAV flight altitude is 1140 m. The multi-target localization results are within the range of allowable error. After we use a lens distortion correction method in a single image, the circular error probability (CEP) of the multi-target localization is reduced by 7%, and 50 targets can be located at the same time. The RLS algorithm can adaptively estimate the location data based on multiple images. Compared with multi-target localization based on a single image, CEP of the multi-target localization using RLS is reduced by 25%. The proposed method can be implemented on a small circuit board to operate in real time. This research is expected to significantly benefit small UAVs which need multi-target geo-location functions.

  6. MFAM: Multiple Frequency Adaptive Model-Based Indoor Localization Method.

    PubMed

    Tuta, Jure; Juric, Matjaz B

    2018-03-24

    This paper presents MFAM (Multiple Frequency Adaptive Model-based localization method), a novel model-based indoor localization method that is capable of using multiple wireless signal frequencies simultaneously. It utilizes indoor architectural model and physical properties of wireless signal propagation through objects and space. The motivation for developing multiple frequency localization method lies in the future Wi-Fi standards (e.g., 802.11ah) and the growing number of various wireless signals present in the buildings (e.g., Wi-Fi, Bluetooth, ZigBee, etc.). Current indoor localization methods mostly rely on a single wireless signal type and often require many devices to achieve the necessary accuracy. MFAM utilizes multiple wireless signal types and improves the localization accuracy over the usage of a single frequency. It continuously monitors signal propagation through space and adapts the model according to the changes indoors. Using multiple signal sources lowers the required number of access points for a specific signal type while utilizing signals, already present in the indoors. Due to the unavailability of the 802.11ah hardware, we have evaluated proposed method with similar signals; we have used 2.4 GHz Wi-Fi and 868 MHz HomeMatic home automation signals. We have performed the evaluation in a modern two-bedroom apartment and measured mean localization error 2.0 to 2.3 m and median error of 2.0 to 2.2 m. Based on our evaluation results, using two different signals improves the localization accuracy by 18% in comparison to 2.4 GHz Wi-Fi-only approach. Additional signals would improve the accuracy even further. We have shown that MFAM provides better accuracy than competing methods, while having several advantages for real-world usage.

  7. MFAM: Multiple Frequency Adaptive Model-Based Indoor Localization Method

    PubMed Central

    Juric, Matjaz B.

    2018-01-01

    This paper presents MFAM (Multiple Frequency Adaptive Model-based localization method), a novel model-based indoor localization method that is capable of using multiple wireless signal frequencies simultaneously. It utilizes indoor architectural model and physical properties of wireless signal propagation through objects and space. The motivation for developing multiple frequency localization method lies in the future Wi-Fi standards (e.g., 802.11ah) and the growing number of various wireless signals present in the buildings (e.g., Wi-Fi, Bluetooth, ZigBee, etc.). Current indoor localization methods mostly rely on a single wireless signal type and often require many devices to achieve the necessary accuracy. MFAM utilizes multiple wireless signal types and improves the localization accuracy over the usage of a single frequency. It continuously monitors signal propagation through space and adapts the model according to the changes indoors. Using multiple signal sources lowers the required number of access points for a specific signal type while utilizing signals, already present in the indoors. Due to the unavailability of the 802.11ah hardware, we have evaluated proposed method with similar signals; we have used 2.4 GHz Wi-Fi and 868 MHz HomeMatic home automation signals. We have performed the evaluation in a modern two-bedroom apartment and measured mean localization error 2.0 to 2.3 m and median error of 2.0 to 2.2 m. Based on our evaluation results, using two different signals improves the localization accuracy by 18% in comparison to 2.4 GHz Wi-Fi-only approach. Additional signals would improve the accuracy even further. We have shown that MFAM provides better accuracy than competing methods, while having several advantages for real-world usage. PMID:29587352

  8. Analysis of Non Local Image Denoising Methods

    NASA Astrophysics Data System (ADS)

    Pardo, Álvaro

    Image denoising is probably one of the most studied problems in the image processing community. Recently a new paradigm on non local denoising was introduced. The Non Local Means method proposed by Buades, Morel and Coll attracted the attention of other researches who proposed improvements and modifications to their proposal. In this work we analyze those methods trying to understand their properties while connecting them to segmentation based on spectral graph properties. We also propose some improvements to automatically estimate the parameters used on these methods.

  9. [EEG source localization using LORETA (low resolution electromagnetic tomography)].

    PubMed

    Puskás, Szilvia

    2011-03-30

    Eledctroencephalography (EEG) has excellent temporal resolution, but the spatial resolution is poor. Different source localization methods exist to solve the so-called inverse problem, thus increasing the accuracy of spatial localization. This paper provides an overview of the history of source localization and the main categories of techniques are discussed. LORETA (low resolution electromagnetic tomography) is introduced in details: technical informations are discussed and localization properties of LORETA method are compared to other inverse solutions. Validation of the method with different imaging techniques is also discussed. This paper reviews several publications using LORETA both in healthy persons and persons with different neurological and psychiatric diseases. Finally future possible applications are discussed.

  10. Brain MRI Tumor Detection using Active Contour Model and Local Image Fitting Energy

    NASA Astrophysics Data System (ADS)

    Nabizadeh, Nooshin; John, Nigel

    2014-03-01

    Automatic abnormality detection in Magnetic Resonance Imaging (MRI) is an important issue in many diagnostic and therapeutic applications. Here an automatic brain tumor detection method is introduced that uses T1-weighted images and K. Zhang et. al.'s active contour model driven by local image fitting (LIF) energy. Local image fitting energy obtains the local image information, which enables the algorithm to segment images with intensity inhomogeneities. Advantage of this method is that the LIF energy functional has less computational complexity than the local binary fitting (LBF) energy functional; moreover, it maintains the sub-pixel accuracy and boundary regularization properties. In Zhang's algorithm, a new level set method based on Gaussian filtering is used to implement the variational formulation, which is not only vigorous to prevent the energy functional from being trapped into local minimum, but also effective in keeping the level set function regular. Experiments show that the proposed method achieves high accuracy brain tumor segmentation results.

  11. Direct mapping of local redox current density on a monolith electrode by laser scanning.

    PubMed

    Lee, Seung-Woo; Lopez, Jeffrey; Saraf, Ravi F

    2013-09-15

    An optical method of mapping local redox reaction over a monolith electrode using simple laser scanning is described. As the optical signal is linearly proportional to the maximum redox current that is measured concomitantly by voltammetry, the optical signal quantitatively maps the local redox current density distribution. The method is demonstrated on two types of reactions: (1) a reversible reaction where the redox moieties are ionic, and (2) an irreversible reaction on two different types of enzymes immobilized on the electrode where the reaction moieties are nonionic. To demonstrate the scanning capability, the local redox behavior on a "V-shaped" electrode is studied where the local length scale and, hence, the local current density, is nonuniform. The ability to measure the current density distribution by this method will pave the way for multianalyte analysis on a monolith electrode using a standard three-electrode configuration. The method is called Scanning Electrometer for Electrical Double-layer (SEED). Copyright © 2013 Elsevier B.V. All rights reserved.

  12. [Local Regression Algorithm Based on Net Analyte Signal and Its Application in Near Infrared Spectral Analysis].

    PubMed

    Zhang, Hong-guang; Lu, Jian-gang

    2016-02-01

    Abstract To overcome the problems of significant difference among samples and nonlinearity between the property and spectra of samples in spectral quantitative analysis, a local regression algorithm is proposed in this paper. In this algorithm, net signal analysis method(NAS) was firstly used to obtain the net analyte signal of the calibration samples and unknown samples, then the Euclidean distance between net analyte signal of the sample and net analyte signal of calibration samples was calculated and utilized as similarity index. According to the defined similarity index, the local calibration sets were individually selected for each unknown sample. Finally, a local PLS regression model was built on each local calibration sets for each unknown sample. The proposed method was applied to a set of near infrared spectra of meat samples. The results demonstrate that the prediction precision and model complexity of the proposed method are superior to global PLS regression method and conventional local regression algorithm based on spectral Euclidean distance.

  13. LocTree2 predicts localization for all domains of life

    PubMed Central

    Goldberg, Tatyana; Hamp, Tobias; Rost, Burkhard

    2012-01-01

    Motivation: Subcellular localization is one aspect of protein function. Despite advances in high-throughput imaging, localization maps remain incomplete. Several methods accurately predict localization, but many challenges remain to be tackled. Results: In this study, we introduced a framework to predict localization in life's three domains, including globular and membrane proteins (3 classes for archaea; 6 for bacteria and 18 for eukaryota). The resulting method, LocTree2, works well even for protein fragments. It uses a hierarchical system of support vector machines that imitates the cascading mechanism of cellular sorting. The method reaches high levels of sustained performance (eukaryota: Q18=65%, bacteria: Q6=84%). LocTree2 also accurately distinguishes membrane and non-membrane proteins. In our hands, it compared favorably with top methods when tested on new data. Availability: Online through PredictProtein (predictprotein.org); as standalone version at http://www.rostlab.org/services/loctree2. Contact: localization@rostlab.org Supplementary Information: Supplementary data are available at Bioinformatics online. PMID:22962467

  14. Structural-change localization and monitoring through a perturbation-based inverse problem.

    PubMed

    Roux, Philippe; Guéguen, Philippe; Baillet, Laurent; Hamze, Alaa

    2014-11-01

    Structural-change detection and characterization, or structural-health monitoring, is generally based on modal analysis, for detection, localization, and quantification of changes in structure. Classical methods combine both variations in frequencies and mode shapes, which require accurate and spatially distributed measurements. In this study, the detection and localization of a local perturbation are assessed by analysis of frequency changes (in the fundamental mode and overtones) that are combined with a perturbation-based linear inverse method and a deconvolution process. This perturbation method is applied first to a bending beam with the change considered as a local perturbation of the Young's modulus, using a one-dimensional finite-element model for modal analysis. Localization is successful, even for extended and multiple changes. In a second step, the method is numerically tested under ambient-noise vibration from the beam support with local changes that are shifted step by step along the beam. The frequency values are revealed using the random decrement technique that is applied to the time-evolving vibrations recorded by one sensor at the free extremity of the beam. Finally, the inversion method is experimentally demonstrated at the laboratory scale with data recorded at the free end of a Plexiglas beam attached to a metallic support.

  15. Method for local temperature measurement in a nanoreactor for in situ high-resolution electron microscopy.

    PubMed

    Vendelbo, S B; Kooyman, P J; Creemer, J F; Morana, B; Mele, L; Dona, P; Nelissen, B J; Helveg, S

    2013-10-01

    In situ high-resolution transmission electron microscopy (TEM) of solids under reactive gas conditions can be facilitated by microelectromechanical system devices called nanoreactors. These nanoreactors are windowed cells containing nanoliter volumes of gas at ambient pressures and elevated temperatures. However, due to the high spatial confinement of the reaction environment, traditional methods for measuring process parameters, such as the local temperature, are difficult to apply. To address this issue, we devise an electron energy loss spectroscopy (EELS) method that probes the local temperature of the reaction volume under inspection by the electron beam. The local gas density, as measured using quantitative EELS, is combined with the inherent relation between gas density and temperature, as described by the ideal gas law, to obtain the local temperature. Using this method we determined the temperature gradient in a nanoreactor in situ, while the average, global temperature was monitored by a traditional measurement of the electrical resistivity of the heater. The local gas temperatures had a maximum of 56 °C deviation from the global heater values under the applied conditions. The local temperatures, obtained with the proposed method, are in good agreement with predictions from an analytical model. Copyright © 2013 Elsevier B.V. All rights reserved.

  16. Hue-preserving and saturation-improved color histogram equalization algorithm.

    PubMed

    Song, Ki Sun; Kang, Hee; Kang, Moon Gi

    2016-06-01

    In this paper, an algorithm is proposed to improve contrast and saturation without color degradation. The local histogram equalization (HE) method offers better performance than the global HE method, whereas the local HE method sometimes produces undesirable results due to the block-based processing. The proposed contrast-enhancement (CE) algorithm reflects the characteristics of the global HE method in the local HE method to avoid the artifacts, while global and local contrasts are enhanced. There are two ways to apply the proposed CE algorithm to color images. One is luminance processing methods, and the other one is each channel processing methods. However, these ways incur excessive or reduced saturation and color degradation problems. The proposed algorithm solves these problems by using channel adaptive equalization and similarity of ratios between the channels. Experimental results show that the proposed algorithm enhances contrast and saturation while preserving the hue and producing better performance than existing methods in terms of objective evaluation metrics.

  17. Multimodal Medical Image Fusion by Adaptive Manifold Filter.

    PubMed

    Geng, Peng; Liu, Shuaiqi; Zhuang, Shanna

    2015-01-01

    Medical image fusion plays an important role in diagnosis and treatment of diseases such as image-guided radiotherapy and surgery. The modified local contrast information is proposed to fuse multimodal medical images. Firstly, the adaptive manifold filter is introduced into filtering source images as the low-frequency part in the modified local contrast. Secondly, the modified spatial frequency of the source images is adopted as the high-frequency part in the modified local contrast. Finally, the pixel with larger modified local contrast is selected into the fused image. The presented scheme outperforms the guided filter method in spatial domain, the dual-tree complex wavelet transform-based method, nonsubsampled contourlet transform-based method, and four classic fusion methods in terms of visual quality. Furthermore, the mutual information values by the presented method are averagely 55%, 41%, and 62% higher than the three methods and those values of edge based similarity measure by the presented method are averagely 13%, 33%, and 14% higher than the three methods for the six pairs of source images.

  18. Multi-Objective Community Detection Based on Memetic Algorithm

    PubMed Central

    2015-01-01

    Community detection has drawn a lot of attention as it can provide invaluable help in understanding the function and visualizing the structure of networks. Since single objective optimization methods have intrinsic drawbacks to identifying multiple significant community structures, some methods formulate the community detection as multi-objective problems and adopt population-based evolutionary algorithms to obtain multiple community structures. Evolutionary algorithms have strong global search ability, but have difficulty in locating local optima efficiently. In this study, in order to identify multiple significant community structures more effectively, a multi-objective memetic algorithm for community detection is proposed by combining multi-objective evolutionary algorithm with a local search procedure. The local search procedure is designed by addressing three issues. Firstly, nondominated solutions generated by evolutionary operations and solutions in dominant population are set as initial individuals for local search procedure. Then, a new direction vector named as pseudonormal vector is proposed to integrate two objective functions together to form a fitness function. Finally, a network specific local search strategy based on label propagation rule is expanded to search the local optimal solutions efficiently. The extensive experiments on both artificial and real-world networks evaluate the proposed method from three aspects. Firstly, experiments on influence of local search procedure demonstrate that the local search procedure can speed up the convergence to better partitions and make the algorithm more stable. Secondly, comparisons with a set of classic community detection methods illustrate the proposed method can find single partitions effectively. Finally, the method is applied to identify hierarchical structures of networks which are beneficial for analyzing networks in multi-resolution levels. PMID:25932646

  19. Multi-objective community detection based on memetic algorithm.

    PubMed

    Wu, Peng; Pan, Li

    2015-01-01

    Community detection has drawn a lot of attention as it can provide invaluable help in understanding the function and visualizing the structure of networks. Since single objective optimization methods have intrinsic drawbacks to identifying multiple significant community structures, some methods formulate the community detection as multi-objective problems and adopt population-based evolutionary algorithms to obtain multiple community structures. Evolutionary algorithms have strong global search ability, but have difficulty in locating local optima efficiently. In this study, in order to identify multiple significant community structures more effectively, a multi-objective memetic algorithm for community detection is proposed by combining multi-objective evolutionary algorithm with a local search procedure. The local search procedure is designed by addressing three issues. Firstly, nondominated solutions generated by evolutionary operations and solutions in dominant population are set as initial individuals for local search procedure. Then, a new direction vector named as pseudonormal vector is proposed to integrate two objective functions together to form a fitness function. Finally, a network specific local search strategy based on label propagation rule is expanded to search the local optimal solutions efficiently. The extensive experiments on both artificial and real-world networks evaluate the proposed method from three aspects. Firstly, experiments on influence of local search procedure demonstrate that the local search procedure can speed up the convergence to better partitions and make the algorithm more stable. Secondly, comparisons with a set of classic community detection methods illustrate the proposed method can find single partitions effectively. Finally, the method is applied to identify hierarchical structures of networks which are beneficial for analyzing networks in multi-resolution levels.

  20. A Hidden Markov Model Approach for Simultaneously Estimating Local Ancestry and Admixture Time Using Next Generation Sequence Data in Samples of Arbitrary Ploidy

    PubMed Central

    Nielsen, Rasmus

    2017-01-01

    Admixture—the mixing of genomes from divergent populations—is increasingly appreciated as a central process in evolution. To characterize and quantify patterns of admixture across the genome, a number of methods have been developed for local ancestry inference. However, existing approaches have a number of shortcomings. First, all local ancestry inference methods require some prior assumption about the expected ancestry tract lengths. Second, existing methods generally require genotypes, which is not feasible to obtain for many next-generation sequencing projects. Third, many methods assume samples are diploid, however a wide variety of sequencing applications will fail to meet this assumption. To address these issues, we introduce a novel hidden Markov model for estimating local ancestry that models the read pileup data, rather than genotypes, is generalized to arbitrary ploidy, and can estimate the time since admixture during local ancestry inference. We demonstrate that our method can simultaneously estimate the time since admixture and local ancestry with good accuracy, and that it performs well on samples of high ploidy—i.e. 100 or more chromosomes. As this method is very general, we expect it will be useful for local ancestry inference in a wider variety of populations than what previously has been possible. We then applied our method to pooled sequencing data derived from populations of Drosophila melanogaster on an ancestry cline on the east coast of North America. We find that regions of local recombination rates are negatively correlated with the proportion of African ancestry, suggesting that selection against foreign ancestry is the least efficient in low recombination regions. Finally we show that clinal outlier loci are enriched for genes associated with gene regulatory functions, consistent with a role of regulatory evolution in ecological adaptation of admixed D. melanogaster populations. Our results illustrate the potential of local ancestry inference for elucidating fundamental evolutionary processes. PMID:28045893

  1. Content based Image Retrieval based on Different Global and Local Color Histogram Methods: A Survey

    NASA Astrophysics Data System (ADS)

    Suhasini, Pallikonda Sarah; Sri Rama Krishna, K.; Murali Krishna, I. V.

    2017-02-01

    Different global and local color histogram methods for content based image retrieval (CBIR) are investigated in this paper. Color histogram is a widely used descriptor for CBIR. Conventional method of extracting color histogram is global, which misses the spatial content, is less invariant to deformation and viewpoint changes, and results in a very large three dimensional histogram corresponding to the color space used. To address the above deficiencies, different global and local histogram methods are proposed in recent research. Different ways of extracting local histograms to have spatial correspondence, invariant colour histogram to add deformation and viewpoint invariance and fuzzy linking method to reduce the size of the histogram are found in recent papers. The color space and the distance metric used are vital in obtaining color histogram. In this paper the performance of CBIR based on different global and local color histograms in three different color spaces, namely, RGB, HSV, L*a*b* and also with three distance measures Euclidean, Quadratic and Histogram intersection are surveyed, to choose appropriate method for future research.

  2. Planning Target Margin Calculations for Prostate Radiotherapy Based on Intrafraction and Interfraction Motion Using Four Localization Methods

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beltran, Chris; Herman, Michael G.; Davis, Brian J.

    2008-01-01

    Purpose: To determine planning target volume (PTV) margins for prostate radiotherapy based on the internal margin (IM) (intrafractional motion) and the setup margin (SM) (interfractional motion) for four daily localization methods: skin marks (tattoo), pelvic bony anatomy (bone), intraprostatic gold seeds using a 5-mm action threshold, and using no threshold. Methods and Materials: Forty prostate cancer patients were treated with external radiotherapy according to an online localization protocol using four intraprostatic gold seeds and electronic portal images (EPIs). Daily localization and treatment EPIs were obtained. These data allowed inter- and intrafractional analysis of prostate motion. The SM for the fourmore » daily localization methods and the IM were determined. Results: A total of 1532 fractions were analyzed. Tattoo localization requires a SM of 6.8 mm left-right (LR), 7.2 mm inferior-superior (IS), and 9.8 mm anterior-posterior (AP). Bone localization requires 3.1, 8.9, and 10.7 mm, respectively. The 5-mm threshold localization requires 4.0, 3.9, and 3.7 mm. No threshold localization requires 3.4, 3.2, and 3.2 mm. The intrafractional prostate motion requires an IM of 2.4 mm LR, 3.4 mm IS and AP. The PTV margin using the 5-mm threshold, including interobserver uncertainty, IM, and SM, is 4.8 mm LR, 5.4 mm IS, and 5.2 mm AP. Conclusions: Localization based on EPI with implanted gold seeds allows a large PTV margin reduction when compared with tattoo localization. Except for the LR direction, bony anatomy localization does not decrease the margins compared with tattoo localization. Intrafractional prostate motion is a limiting factor on margin reduction.« less

  3. Point cloud registration from local feature correspondences-Evaluation on challenging datasets.

    PubMed

    Petricek, Tomas; Svoboda, Tomas

    2017-01-01

    Registration of laser scans, or point clouds in general, is a crucial step of localization and mapping with mobile robots or in object modeling pipelines. A coarse alignment of the point clouds is generally needed before applying local methods such as the Iterative Closest Point (ICP) algorithm. We propose a feature-based approach to point cloud registration and evaluate the proposed method and its individual components on challenging real-world datasets. For a moderate overlap between the laser scans, the method provides a superior registration accuracy compared to state-of-the-art methods including Generalized ICP, 3D Normal-Distribution Transform, Fast Point-Feature Histograms, and 4-Points Congruent Sets. Compared to the surface normals, the points as the underlying features yield higher performance in both keypoint detection and establishing local reference frames. Moreover, sign disambiguation of the basis vectors proves to be an important aspect in creating repeatable local reference frames. A novel method for sign disambiguation is proposed which yields highly repeatable reference frames.

  4. Fourth order exponential time differencing method with local discontinuous Galerkin approximation for coupled nonlinear Schrodinger equations

    DOE PAGES

    Liang, Xiao; Khaliq, Abdul Q. M.; Xing, Yulong

    2015-01-23

    In this paper, we study a local discontinuous Galerkin method combined with fourth order exponential time differencing Runge-Kutta time discretization and a fourth order conservative method for solving the nonlinear Schrödinger equations. Based on different choices of numerical fluxes, we propose both energy-conserving and energy-dissipative local discontinuous Galerkin methods, and have proven the error estimates for the semi-discrete methods applied to linear Schrödinger equation. The numerical methods are proven to be highly efficient and stable for long-range soliton computations. Finally, extensive numerical examples are provided to illustrate the accuracy, efficiency and reliability of the proposed methods.

  5. DLocalMotif: a discriminative approach for discovering local motifs in protein sequences.

    PubMed

    Mehdi, Ahmed M; Sehgal, Muhammad Shoaib B; Kobe, Bostjan; Bailey, Timothy L; Bodén, Mikael

    2013-01-01

    Local motifs are patterns of DNA or protein sequences that occur within a sequence interval relative to a biologically defined anchor or landmark. Current protein motif discovery methods do not adequately consider such constraints to identify biologically significant motifs that are only weakly over-represented but spatially confined. Using negatives, i.e. sequences known to not contain a local motif, can further increase the specificity of their discovery. This article introduces the method DLocalMotif that makes use of positional information and negative data for local motif discovery in protein sequences. DLocalMotif combines three scoring functions, measuring degrees of motif over-representation, entropy and spatial confinement, specifically designed to discriminatively exploit the availability of negative data. The method is shown to outperform current methods that use only a subset of these motif characteristics. We apply the method to several biological datasets. The analysis of peroxisomal targeting signals uncovers several novel motifs that occur immediately upstream of the dominant peroxisomal targeting signal-1 signal. The analysis of proline-tyrosine nuclear localization signals uncovers multiple novel motifs that overlap with C2H2 zinc finger domains. We also evaluate the method on classical nuclear localization signals and endoplasmic reticulum retention signals and find that DLocalMotif successfully recovers biologically relevant sequence properties. http://bioinf.scmb.uq.edu.au/dlocalmotif/

  6. Guided SAR image despeckling with probabilistic non local weights

    NASA Astrophysics Data System (ADS)

    Gokul, Jithin; Nair, Madhu S.; Rajan, Jeny

    2017-12-01

    SAR images are generally corrupted by granular disturbances called speckle, which makes visual analysis and detail extraction a difficult task. Non Local despeckling techniques with probabilistic similarity has been a recent trend in SAR despeckling. To achieve effective speckle suppression without compromising detail preservation, we propose an improvement for the existing Generalized Guided Filter with Bayesian Non-Local Means (GGF-BNLM) method. The proposed method (Guided SAR Image Despeckling with Probabilistic Non Local Weights) replaces parametric constants based on heuristics in GGF-BNLM method with dynamically derived values based on the image statistics for weight computation. Proposed changes make GGF-BNLM method adaptive and as a result, significant improvement is achieved in terms of performance. Experimental analysis on SAR images shows excellent speckle reduction without compromising feature preservation when compared to GGF-BNLM method. Results are also compared with other state-of-the-art and classic SAR depseckling techniques to demonstrate the effectiveness of the proposed method.

  7. Real-time localization of mobile device by filtering method for sensor fusion

    NASA Astrophysics Data System (ADS)

    Fuse, Takashi; Nagara, Keita

    2017-06-01

    Most of the applications with mobile devices require self-localization of the devices. GPS cannot be used in indoor environment, the positions of mobile devices are estimated autonomously by using IMU. Since the self-localization is based on IMU of low accuracy, and then the self-localization in indoor environment is still challenging. The selflocalization method using images have been developed, and the accuracy of the method is increasing. This paper develops the self-localization method without GPS in indoor environment by integrating sensors, such as IMU and cameras, on mobile devices simultaneously. The proposed method consists of observations, forecasting and filtering. The position and velocity of the mobile device are defined as a state vector. In the self-localization, observations correspond to observation data from IMU and camera (observation vector), forecasting to mobile device moving model (system model) and filtering to tracking method by inertial surveying and coplanarity condition and inverse depth model (observation model). Positions of a mobile device being tracked are estimated by system model (forecasting step), which are assumed as linearly moving model. Then estimated positions are optimized referring to the new observation data based on likelihood (filtering step). The optimization at filtering step corresponds to estimation of the maximum a posterior probability. Particle filter are utilized for the calculation through forecasting and filtering steps. The proposed method is applied to data acquired by mobile devices in indoor environment. Through the experiments, the high performance of the method is confirmed.

  8. Speeding up local correlation methods

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kats, Daniel

    2014-12-28

    We present two techniques that can substantially speed up the local correlation methods. The first one allows one to avoid the expensive transformation of the electron-repulsion integrals from atomic orbitals to virtual space. The second one introduces an algorithm for the residual equations in the local perturbative treatment that, in contrast to the standard scheme, does not require holding the amplitudes or residuals in memory. It is shown that even an interpreter-based implementation of the proposed algorithm in the context of local MP2 method is faster and requires less memory than the highly optimized variants of conventional algorithms.

  9. Boosting instance prototypes to detect local dermoscopic features.

    PubMed

    Situ, Ning; Yuan, Xiaojing; Zouridakis, George

    2010-01-01

    Local dermoscopic features are useful in many dermoscopic criteria for skin cancer detection. We address the problem of detecting local dermoscopic features from epiluminescence (ELM) microscopy skin lesion images. We formulate the recognition of local dermoscopic features as a multi-instance learning (MIL) problem. We employ the method of diverse density (DD) and evidence confidence (EC) function to convert MIL to a single-instance learning (SIL) problem. We apply Adaboost to improve the classification performance with support vector machines (SVMs) as the base classifier. We also propose to boost the selection of instance prototypes through changing the data weights in the DD function. We validate the methods on detecting ten local dermoscopic features from a dataset with 360 images. We compare the performance of the MIL approach, its boosting version, and a baseline method without using MIL. Our results show that boosting can provide performance improvement compared to the other two methods.

  10. A microwave imaging-based 3D localization algorithm for an in-body RF source as in wireless capsule endoscopes.

    PubMed

    Chandra, Rohit; Balasingham, Ilangko

    2015-01-01

    A microwave imaging-based technique for 3D localization of an in-body RF source is presented. Such a technique can be useful for localization of an RF source as in wireless capsule endoscopes for positioning of any abnormality in the gastrointestinal tract. Microwave imaging is used to determine the dielectric properties (relative permittivity and conductivity) of the tissues that are required for a precise localization. A 2D microwave imaging algorithm is used for determination of the dielectric properties. Calibration method is developed for removing any error due to the used 2D imaging algorithm on the imaging data of a 3D body. The developed method is tested on a simple 3D heterogeneous phantom through finite-difference-time-domain simulations. Additive white Gaussian noise at the signal-to-noise ratio of 30 dB is added to the simulated data to make them more realistic. The developed calibration method improves the imaging and the localization accuracy. Statistics on the localization accuracy are generated by randomly placing the RF source at various positions inside the small intestine of the phantom. The cumulative distribution function of the localization error is plotted. In 90% of the cases, the localization accuracy was found within 1.67 cm, showing the capability of the developed method for 3D localization.

  11. Cost-Sensitive Local Binary Feature Learning for Facial Age Estimation.

    PubMed

    Lu, Jiwen; Liong, Venice Erin; Zhou, Jie

    2015-12-01

    In this paper, we propose a cost-sensitive local binary feature learning (CS-LBFL) method for facial age estimation. Unlike the conventional facial age estimation methods that employ hand-crafted descriptors or holistically learned descriptors for feature representation, our CS-LBFL method learns discriminative local features directly from raw pixels for face representation. Motivated by the fact that facial age estimation is a cost-sensitive computer vision problem and local binary features are more robust to illumination and expression variations than holistic features, we learn a series of hashing functions to project raw pixel values extracted from face patches into low-dimensional binary codes, where binary codes with similar chronological ages are projected as close as possible, and those with dissimilar chronological ages are projected as far as possible. Then, we pool and encode these local binary codes within each face image as a real-valued histogram feature for face representation. Moreover, we propose a cost-sensitive local binary multi-feature learning method to jointly learn multiple sets of hashing functions using face patches extracted from different scales to exploit complementary information. Our methods achieve competitive performance on four widely used face aging data sets.

  12. Local coding based matching kernel method for image classification.

    PubMed

    Song, Yan; McLoughlin, Ian Vince; Dai, Li-Rong

    2014-01-01

    This paper mainly focuses on how to effectively and efficiently measure visual similarity for local feature based representation. Among existing methods, metrics based on Bag of Visual Word (BoV) techniques are efficient and conceptually simple, at the expense of effectiveness. By contrast, kernel based metrics are more effective, but at the cost of greater computational complexity and increased storage requirements. We show that a unified visual matching framework can be developed to encompass both BoV and kernel based metrics, in which local kernel plays an important role between feature pairs or between features and their reconstruction. Generally, local kernels are defined using Euclidean distance or its derivatives, based either explicitly or implicitly on an assumption of Gaussian noise. However, local features such as SIFT and HoG often follow a heavy-tailed distribution which tends to undermine the motivation behind Euclidean metrics. Motivated by recent advances in feature coding techniques, a novel efficient local coding based matching kernel (LCMK) method is proposed. This exploits the manifold structures in Hilbert space derived from local kernels. The proposed method combines advantages of both BoV and kernel based metrics, and achieves a linear computational complexity. This enables efficient and scalable visual matching to be performed on large scale image sets. To evaluate the effectiveness of the proposed LCMK method, we conduct extensive experiments with widely used benchmark datasets, including 15-Scenes, Caltech101/256, PASCAL VOC 2007 and 2011 datasets. Experimental results confirm the effectiveness of the relatively efficient LCMK method.

  13. Sparse reconstruction localization of multiple acoustic emissions in large diameter pipelines

    NASA Astrophysics Data System (ADS)

    Dubuc, Brennan; Ebrahimkhanlou, Arvin; Salamone, Salvatore

    2017-04-01

    A sparse reconstruction localization method is proposed, which is capable of localizing multiple acoustic emission events occurring closely in time. The events may be due to a number of sources, such as the growth of corrosion patches or cracks. Such acoustic emissions may yield localization failure if a triangulation method is used. The proposed method is implemented both theoretically and experimentally on large diameter thin-walled pipes. Experimental examples are presented, which demonstrate the failure of a triangulation method when multiple sources are present in this structure, while highlighting the capabilities of the proposed method. The examples are generated from experimental data of simulated acoustic emission events. The data corresponds to helical guided ultrasonic waves generated in a 3 m long large diameter pipe by pencil lead breaks on its outer surface. Acoustic emission waveforms are recorded by six sparsely distributed low-profile piezoelectric transducers instrumented on the outer surface of the pipe. The same array of transducers is used for both the proposed and the triangulation method. It is demonstrated that the proposed method is able to localize multiple events occurring closely in time. Furthermore, the matching pursuit algorithm and the basis pursuit densoising approach are each evaluated as potential numerical tools in the proposed sparse reconstruction method.

  14. A novel segmentation method for uneven lighting image with noise injection based on non-local spatial information and intuitionistic fuzzy entropy

    NASA Astrophysics Data System (ADS)

    Yu, Haiyan; Fan, Jiulun

    2017-12-01

    Local thresholding methods for uneven lighting image segmentation always have the limitations that they are very sensitive to noise injection and that the performance relies largely upon the choice of the initial window size. This paper proposes a novel algorithm for segmenting uneven lighting images with strong noise injection based on non-local spatial information and intuitionistic fuzzy theory. We regard an image as a gray wave in three-dimensional space, which is composed of many peaks and troughs, and these peaks and troughs can divide the image into many local sub-regions in different directions. Our algorithm computes the relative characteristic of each pixel located in the corresponding sub-region based on fuzzy membership function and uses it to replace its absolute characteristic (its gray level) to reduce the influence of uneven light on image segmentation. At the same time, the non-local adaptive spatial constraints of pixels are introduced to avoid noise interference with the search of local sub-regions and the computation of local characteristics. Moreover, edge information is also taken into account to avoid false peak and trough labeling. Finally, a global method based on intuitionistic fuzzy entropy is employed on the wave transformation image to obtain the segmented result. Experiments on several test images show that the proposed method has excellent capability of decreasing the influence of uneven illumination on images and noise injection and behaves more robustly than several classical global and local thresholding methods.

  15. Age as a Determinant to Select an Anesthesia Method for Tympanostomy Tube Insertion in a Pediatric Population

    PubMed Central

    Jung, Kihwan; Kim, Hojong

    2015-01-01

    Background and Objectives To evaluate the relationship between age and anesthesia method used for tympanostomy tube insertion (TTI) and to provide evidence to guide the selection of an appropriate anesthesia method in children. Subjects and Methods We performed a retrospective review of children under 15 years of age who underwent tympanostomy tube insertion (n=159) or myringotomy alone (n=175) under local or general anesthesia by a single surgeon at a university-based, secondary care referral hospital. Epidermiologic data between local and general anesthesia groups as well as between TTI and myringotomy were analyzed. Medical costs were compared between local and general anesthesia groups. Results Children who received local anesthesia were significantly older than those who received general anesthesia. Unilateral tympanostomy tube insertion was performed more frequently under local anesthesia than bilateral. Logistic regression modeling showed that local anesthesia was more frequently applied in older children (odds ratio=1.041) and for unilateral tympanostomy tube insertion (odds ratio=8.990). The cut-off value of age for local anesthesia was roughly 5 years. Conclusions In a pediatric population at a single medical center, age and whether unilateral or bilateral procedures were required were important factors in selecting an anesthesia method for tympanostomy tube insertion. Our findings suggest that local anesthesia can be preferentially considered for children 5 years of age or older, especially in those with unilateral otitis media with effusion. PMID:26185791

  16. Optoelectronic scanning system upgrade by energy center localization methods

    NASA Astrophysics Data System (ADS)

    Flores-Fuentes, W.; Sergiyenko, O.; Rodriguez-Quiñonez, J. C.; Rivas-López, M.; Hernández-Balbuena, D.; Básaca-Preciado, L. C.; Lindner, L.; González-Navarro, F. F.

    2016-11-01

    A problem of upgrading an optoelectronic scanning system with digital post-processing of the signal based on adequate methods of energy center localization is considered. An improved dynamic triangulation analysis technique is proposed by an example of industrial infrastructure damage detection. A modification of our previously published method aimed at searching for the energy center of an optoelectronic signal is described. Application of the artificial intelligence algorithm of compensation for the error of determining the angular coordinate in calculating the spatial coordinate through dynamic triangulation is demonstrated. Five energy center localization methods are developed and tested to select the best method. After implementation of these methods, digital compensation for the measurement error, and statistical data analysis, a non-parametric behavior of the data is identified. The Wilcoxon signed rank test is applied to improve the result further. For optical scanning systems, it is necessary to detect a light emitter mounted on the infrastructure being investigated to calculate its spatial coordinate by the energy center localization method.

  17. The Cauchy Problem in Local Spaces for the Complex Ginzburg-Landau EquationII. Contraction Methods

    NASA Astrophysics Data System (ADS)

    Ginibre, J.; Velo, G.

    We continue the study of the initial value problem for the complex Ginzburg-Landau equation (with a > 0, b > 0, g>= 0) in initiated in a previous paper [I]. We treat the case where the initial data and the solutions belong to local uniform spaces, more precisely to spaces of functions satisfying local regularity conditions and uniform bounds in local norms, but no decay conditions (or arbitrarily weak decay conditions) at infinity in . In [I] we used compactness methods and an extended version of recent local estimates [3] and proved in particular the existence of solutions globally defined in time with local regularity of the initial data corresponding to the spaces Lr for r>= 2 or H1. Here we treat the same problem by contraction methods. This allows us in particular to prove that the solutions obtained in [I] are unique under suitable subcriticality conditions, and to obtain for them additional regularity properties and uniform bounds. The method extends some of those previously applied to the nonlinear heat equation in global spaces to the framework of local uniform spaces.

  18. Iterative Nonlocal Total Variation Regularization Method for Image Restoration

    PubMed Central

    Xu, Huanyu; Sun, Quansen; Luo, Nan; Cao, Guo; Xia, Deshen

    2013-01-01

    In this paper, a Bregman iteration based total variation image restoration algorithm is proposed. Based on the Bregman iteration, the algorithm splits the original total variation problem into sub-problems that are easy to solve. Moreover, non-local regularization is introduced into the proposed algorithm, and a method to choose the non-local filter parameter locally and adaptively is proposed. Experiment results show that the proposed algorithms outperform some other regularization methods. PMID:23776560

  19. Drawing simulation by static implicit analysis with the artificial damping method

    NASA Astrophysics Data System (ADS)

    Oide, K.; Mihara, Y.; Kobayashi, T.; Takizawa, H.; Amaishi, T.; Umezu, Y.

    2016-08-01

    Wrinkling during draw is typically a local instability problem. When the structural instability is localized, there will be a local transfer of strain energy from one part of the structure to neighboring parts, and global solution methods, which is typically represented by the arc length method, may not work. So, this type of problems has to be solved either dynamically or with the artificial damping. On the other hand, the essential nature of the buckling behavior can be regarded as a static problem, even though it may be possible to raise some side issues due to the inertia effect. In this study, we traced the local buckling behavior of anisotropic elasto-plastic thin shells in Numisheet2014 BM4 using the artificial damping method.

  20. MEG source localization of spatially extended generators of epileptic activity: comparing entropic and hierarchical bayesian approaches.

    PubMed

    Chowdhury, Rasheda Arman; Lina, Jean Marc; Kobayashi, Eliane; Grova, Christophe

    2013-01-01

    Localizing the generators of epileptic activity in the brain using Electro-EncephaloGraphy (EEG) or Magneto-EncephaloGraphy (MEG) signals is of particular interest during the pre-surgical investigation of epilepsy. Epileptic discharges can be detectable from background brain activity, provided they are associated with spatially extended generators. Using realistic simulations of epileptic activity, this study evaluates the ability of distributed source localization methods to accurately estimate the location of the generators and their sensitivity to the spatial extent of such generators when using MEG data. Source localization methods based on two types of realistic models have been investigated: (i) brain activity may be modeled using cortical parcels and (ii) brain activity is assumed to be locally smooth within each parcel. A Data Driven Parcellization (DDP) method was used to segment the cortical surface into non-overlapping parcels and diffusion-based spatial priors were used to model local spatial smoothness within parcels. These models were implemented within the Maximum Entropy on the Mean (MEM) and the Hierarchical Bayesian (HB) source localization frameworks. We proposed new methods in this context and compared them with other standard ones using Monte Carlo simulations of realistic MEG data involving sources of several spatial extents and depths. Detection accuracy of each method was quantified using Receiver Operating Characteristic (ROC) analysis and localization error metrics. Our results showed that methods implemented within the MEM framework were sensitive to all spatial extents of the sources ranging from 3 cm(2) to 30 cm(2), whatever were the number and size of the parcels defining the model. To reach a similar level of accuracy within the HB framework, a model using parcels larger than the size of the sources should be considered.

  1. Calculation of wave-functions with frozen orbitals in mixed quantum mechanics/molecular mechanics methods. II. Application of the local basis equation.

    PubMed

    Ferenczy, György G

    2013-04-05

    The application of the local basis equation (Ferenczy and Adams, J. Chem. Phys. 2009, 130, 134108) in mixed quantum mechanics/molecular mechanics (QM/MM) and quantum mechanics/quantum mechanics (QM/QM) methods is investigated. This equation is suitable to derive local basis nonorthogonal orbitals that minimize the energy of the system and it exhibits good convergence properties in a self-consistent field solution. These features make the equation appropriate to be used in mixed QM/MM and QM/QM methods to optimize orbitals in the field of frozen localized orbitals connecting the subsystems. Calculations performed for several properties in divers systems show that the method is robust with various choices of the frozen orbitals and frontier atom properties. With appropriate basis set assignment, it gives results equivalent with those of a related approach [G. G. Ferenczy previous paper in this issue] using the Huzinaga equation. Thus, the local basis equation can be used in mixed QM/MM methods with small size quantum subsystems to calculate properties in good agreement with reference Hartree-Fock-Roothaan results. It is shown that bond charges are not necessary when the local basis equation is applied, although they are required for the self-consistent field solution of the Huzinaga equation based method. Conversely, the deformation of the wave-function near to the boundary is observed without bond charges and this has a significant effect on deprotonation energies but a less pronounced effect when the total charge of the system is conserved. The local basis equation can also be used to define a two layer quantum system with nonorthogonal localized orbitals surrounding the central delocalized quantum subsystem. Copyright © 2013 Wiley Periodicals, Inc.

  2. MEG Source Localization of Spatially Extended Generators of Epileptic Activity: Comparing Entropic and Hierarchical Bayesian Approaches

    PubMed Central

    Chowdhury, Rasheda Arman; Lina, Jean Marc; Kobayashi, Eliane; Grova, Christophe

    2013-01-01

    Localizing the generators of epileptic activity in the brain using Electro-EncephaloGraphy (EEG) or Magneto-EncephaloGraphy (MEG) signals is of particular interest during the pre-surgical investigation of epilepsy. Epileptic discharges can be detectable from background brain activity, provided they are associated with spatially extended generators. Using realistic simulations of epileptic activity, this study evaluates the ability of distributed source localization methods to accurately estimate the location of the generators and their sensitivity to the spatial extent of such generators when using MEG data. Source localization methods based on two types of realistic models have been investigated: (i) brain activity may be modeled using cortical parcels and (ii) brain activity is assumed to be locally smooth within each parcel. A Data Driven Parcellization (DDP) method was used to segment the cortical surface into non-overlapping parcels and diffusion-based spatial priors were used to model local spatial smoothness within parcels. These models were implemented within the Maximum Entropy on the Mean (MEM) and the Hierarchical Bayesian (HB) source localization frameworks. We proposed new methods in this context and compared them with other standard ones using Monte Carlo simulations of realistic MEG data involving sources of several spatial extents and depths. Detection accuracy of each method was quantified using Receiver Operating Characteristic (ROC) analysis and localization error metrics. Our results showed that methods implemented within the MEM framework were sensitive to all spatial extents of the sources ranging from 3 cm2 to 30 cm2, whatever were the number and size of the parcels defining the model. To reach a similar level of accuracy within the HB framework, a model using parcels larger than the size of the sources should be considered. PMID:23418485

  3. Wavelet filter analysis of local atmospheric pressure effects in the long-period tidal bands

    NASA Astrophysics Data System (ADS)

    Hu, X.-G.; Liu, L. T.; Ducarme, B.; Hsu, H. T.; Sun, H.-P.

    2006-11-01

    It is well known that local atmospheric pressure variations obviously affect the observation of short-period Earth tides, such as diurnal tides, semi-diurnal tides and ter-diurnal tides, but local atmospheric pressure effects on the long-period Earth tides have not been studied in detail. This is because the local atmospheric pressure is believed not to be sufficient for an effective pressure correction in long-period tidal bands, and there are no efficient methods to investigate local atmospheric effects in these bands. The usual tidal analysis software package, such as ETERNA, Baytap-G and VAV, cannot provide detailed pressure admittances for long-period tidal bands. We propose a wavelet method to investigate local atmospheric effects on gravity variations in long-period tidal bands. This method constructs efficient orthogonal filter bank with Daubechies wavelets of high vanishing moments. The main advantage of the wavelet filter bank is that it has excellent low frequency response and efficiently suppresses instrumental drift of superconducting gravimeters (SGs) without using any mathematical model. Applying the wavelet method to the 13-year continuous gravity observations from SG T003 in Brussels, Belgium, we filtered 12 long-period tidal groups into eight narrow frequency bands. Wavelet method demonstrates that local atmospheric pressure fluctuations are highly correlated with the noise of SG measurements in the period band 4-40 days with correlation coefficients higher than 0.95 and local atmospheric pressure variations are the main error source for the determination of the tidal parameters in these bands. We show the significant improvement of long-period tidal parameters provided by wavelet method in term of precision.

  4. Localized diabatization applied to excitons in molecular crystals

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jin, Zuxin; Subotnik, Joseph E.

    Traditional ab initio electronic structure calculations of periodic systems yield delocalized eigenstates that should be understood as adiabatic states. For example, excitons are bands of extended states which superimpose localized excitations on every lattice site. However, in general, in order to study the effects of nuclear motion on exciton transport, it is standard to work with a localized description of excitons, especially in a hopping regime; even in a band regime, a localized description can be helpful. To extract localized excitons from a band requires essentially a diabatization procedure. In this paper, three distinct methods are proposed for such localizedmore » diabatization: (i) a simple projection method, (ii) a more general Pipek-Mezey localization scheme, and (iii) a variant of Boys diabatization. Approaches (i) and (ii) require localized, single-particle Wannier orbitals, while approach (iii) has no such dependence. Lastly, these methods should be very useful for studying energy transfer through solids with ab initio calculations.« less

  5. Localized diabatization applied to excitons in molecular crystals

    DOE PAGES

    Jin, Zuxin; Subotnik, Joseph E.

    2017-06-28

    Traditional ab initio electronic structure calculations of periodic systems yield delocalized eigenstates that should be understood as adiabatic states. For example, excitons are bands of extended states which superimpose localized excitations on every lattice site. However, in general, in order to study the effects of nuclear motion on exciton transport, it is standard to work with a localized description of excitons, especially in a hopping regime; even in a band regime, a localized description can be helpful. To extract localized excitons from a band requires essentially a diabatization procedure. In this paper, three distinct methods are proposed for such localizedmore » diabatization: (i) a simple projection method, (ii) a more general Pipek-Mezey localization scheme, and (iii) a variant of Boys diabatization. Approaches (i) and (ii) require localized, single-particle Wannier orbitals, while approach (iii) has no such dependence. Lastly, these methods should be very useful for studying energy transfer through solids with ab initio calculations.« less

  6. The Green's functions for peridynamic non-local diffusion.

    PubMed

    Wang, L J; Xu, J F; Wang, J X

    2016-09-01

    In this work, we develop the Green's function method for the solution of the peridynamic non-local diffusion model in which the spatial gradient of the generalized potential in the classical theory is replaced by an integral of a generalized response function in a horizon. We first show that the general solutions of the peridynamic non-local diffusion model can be expressed as functionals of the corresponding Green's functions for point sources, along with volume constraints for non-local diffusion. Then, we obtain the Green's functions by the Fourier transform method for unsteady and steady diffusions in infinite domains. We also demonstrate that the peridynamic non-local solutions converge to the classical differential solutions when the non-local length approaches zero. Finally, the peridynamic analytical solutions are applied to an infinite plate heated by a Gauss source, and the predicted variations of temperature are compared with the classical local solutions. The peridynamic non-local diffusion model predicts a lower rate of variation of the field quantities than that of the classical theory, which is consistent with experimental observations. The developed method is applicable to general diffusion-type problems.

  7. A Reverse Localization Scheme for Underwater Acoustic Sensor Networks

    PubMed Central

    Moradi, Marjan; Rezazadeh, Javad; Ismail, Abdul Samad

    2012-01-01

    Underwater Wireless Sensor Networks (UWSNs) provide new opportunities to observe and predict the behavior of aquatic environments. In some applications like target tracking or disaster prevention, sensed data is meaningless without location information. In this paper, we propose a novel 3D centralized, localization scheme for mobile underwater wireless sensor network, named Reverse Localization Scheme or RLS in short. RLS is an event-driven localization method triggered by detector sensors for launching localization process. RLS is suitable for surveillance applications that require very fast reactions to events and could report the location of the occurrence. In this method, mobile sensor nodes report the event toward the surface anchors as soon as they detect it. They do not require waiting to receive location information from anchors. Simulation results confirm that the proposed scheme improves the energy efficiency and reduces significantly localization response time with a proper level of accuracy in terms of mobility model of water currents. Major contributions of this method lie on reducing the numbers of message exchange for localization, saving the energy and decreasing the average localization response time. PMID:22666034

  8. A reverse localization scheme for underwater acoustic sensor networks.

    PubMed

    Moradi, Marjan; Rezazadeh, Javad; Ismail, Abdul Samad

    2012-01-01

    Underwater Wireless Sensor Networks (UWSNs) provide new opportunities to observe and predict the behavior of aquatic environments. In some applications like target tracking or disaster prevention, sensed data is meaningless without location information. In this paper, we propose a novel 3D centralized, localization scheme for mobile underwater wireless sensor network, named Reverse Localization Scheme or RLS in short. RLS is an event-driven localization method triggered by detector sensors for launching localization process. RLS is suitable for surveillance applications that require very fast reactions to events and could report the location of the occurrence. In this method, mobile sensor nodes report the event toward the surface anchors as soon as they detect it. They do not require waiting to receive location information from anchors. Simulation results confirm that the proposed scheme improves the energy efficiency and reduces significantly localization response time with a proper level of accuracy in terms of mobility model of water currents. Major contributions of this method lie on reducing the numbers of message exchange for localization, saving the energy and decreasing the average localization response time.

  9. Oscillator strengths, first-order properties, and nuclear gradients for local ADC(2).

    PubMed

    Schütz, Martin

    2015-06-07

    We describe theory and implementation of oscillator strengths, orbital-relaxed first-order properties, and nuclear gradients for the local algebraic diagrammatic construction scheme through second order. The formalism is derived via time-dependent linear response theory based on a second-order unitary coupled cluster model. The implementation presented here is a modification of our previously developed algorithms for Laplace transform based local time-dependent coupled cluster linear response (CC2LR); the local approximations thus are state specific and adaptive. The symmetry of the Jacobian leads to considerable simplifications relative to the local CC2LR method; as a result, a gradient evaluation is about four times less expensive. Test calculations show that in geometry optimizations, usually very similar geometries are obtained as with the local CC2LR method (provided that a second-order method is applicable). As an exemplary application, we performed geometry optimizations on the low-lying singlet states of chlorophyllide a.

  10. Hierarchical Feature Extraction With Local Neural Response for Image Recognition.

    PubMed

    Li, Hong; Wei, Yantao; Li, Luoqing; Chen, C L P

    2013-04-01

    In this paper, a hierarchical feature extraction method is proposed for image recognition. The key idea of the proposed method is to extract an effective feature, called local neural response (LNR), of the input image with nontrivial discrimination and invariance properties by alternating between local coding and maximum pooling operation. The local coding, which is carried out on the locally linear manifold, can extract the salient feature of image patches and leads to a sparse measure matrix on which maximum pooling is carried out. The maximum pooling operation builds the translation invariance into the model. We also show that other invariant properties, such as rotation and scaling, can be induced by the proposed model. In addition, a template selection algorithm is presented to reduce computational complexity and to improve the discrimination ability of the LNR. Experimental results show that our method is robust to local distortion and clutter compared with state-of-the-art algorithms.

  11. Shaping up the protein folding funnel by local interaction: lesson from a structure prediction study.

    PubMed

    Chikenji, George; Fujitsuka, Yoshimi; Takada, Shoji

    2006-02-28

    Predicting protein tertiary structure by folding-like simulations is one of the most stringent tests of how much we understand the principle of protein folding. Currently, the most successful method for folding-based structure prediction is the fragment assembly (FA) method. Here, we address why the FA method is so successful and its lesson for the folding problem. To do so, using the FA method, we designed a structure prediction test of "chimera proteins." In the chimera proteins, local structural preference is specific to the target sequences, whereas nonlocal interactions are only sequence-independent compaction forces. We find that these chimera proteins can find the native folds of the intact sequences with high probability indicating dominant roles of the local interactions. We further explore roles of local structural preference by exact calculation of the HP lattice model of proteins. From these results, we suggest principles of protein folding: For small proteins, compact structures that are fully compatible with local structural preference are few, one of which is the native fold. These local biases shape up the funnel-like energy landscape.

  12. Shaping up the protein folding funnel by local interaction: Lesson from a structure prediction study

    PubMed Central

    Chikenji, George; Fujitsuka, Yoshimi; Takada, Shoji

    2006-01-01

    Predicting protein tertiary structure by folding-like simulations is one of the most stringent tests of how much we understand the principle of protein folding. Currently, the most successful method for folding-based structure prediction is the fragment assembly (FA) method. Here, we address why the FA method is so successful and its lesson for the folding problem. To do so, using the FA method, we designed a structure prediction test of “chimera proteins.” In the chimera proteins, local structural preference is specific to the target sequences, whereas nonlocal interactions are only sequence-independent compaction forces. We find that these chimera proteins can find the native folds of the intact sequences with high probability indicating dominant roles of the local interactions. We further explore roles of local structural preference by exact calculation of the HP lattice model of proteins. From these results, we suggest principles of protein folding: For small proteins, compact structures that are fully compatible with local structural preference are few, one of which is the native fold. These local biases shape up the funnel-like energy landscape. PMID:16488978

  13. A single frequency component-based re-estimated MUSIC algorithm for impact localization on complex composite structures

    NASA Astrophysics Data System (ADS)

    Yuan, Shenfang; Bao, Qiao; Qiu, Lei; Zhong, Yongteng

    2015-10-01

    The growing use of composite materials on aircraft structures has attracted much attention for impact monitoring as a kind of structural health monitoring (SHM) method. Multiple signal classification (MUSIC)-based monitoring technology is a promising method because of its directional scanning ability and easy arrangement of the sensor array. However, for applications on real complex structures, some challenges still exist. The impact-induced elastic waves usually exhibit a wide-band performance, giving rise to the difficulty in obtaining the phase velocity directly. In addition, composite structures usually have obvious anisotropy, and the complex structural style of real aircrafts further enhances this performance, which greatly reduces the localization precision of the MUSIC-based method. To improve the MUSIC-based impact monitoring method, this paper first analyzes and demonstrates the influence of measurement precision of the phase velocity on the localization results of the MUSIC impact localization method. In order to improve the accuracy of the phase velocity measurement, a single frequency component extraction method is presented. Additionally, a single frequency component-based re-estimated MUSIC (SFCBR-MUSIC) algorithm is proposed to reduce the localization error caused by the anisotropy of the complex composite structure. The proposed method is verified on a real composite aircraft wing box, which has T-stiffeners and screw holes. Three typical categories of 41 impacts are monitored. Experimental results show that the SFCBR-MUSIC algorithm can localize impact on complex composite structures with an obviously improved accuracy.

  14. Prediction of protein subcellular localization by weighted gene ontology terms.

    PubMed

    Chi, Sang-Mun

    2010-08-27

    We develop a new weighting approach of gene ontology (GO) terms for predicting protein subcellular localization. The weights of individual GO terms, corresponding to their contribution to the prediction algorithm, are determined by the term-weighting methods used in text categorization. We evaluate several term-weighting methods, which are based on inverse document frequency, information gain, gain ratio, odds ratio, and chi-square and its variants. Additionally, we propose a new term-weighting method based on the logarithmic transformation of chi-square. The proposed term-weighting method performs better than other term-weighting methods, and also outperforms state-of-the-art subcellular prediction methods. Our proposed method achieves 98.1%, 99.3%, 98.1%, 98.1%, and 95.9% overall accuracies for the animal BaCelLo independent dataset (IDS), fungal BaCelLo IDS, animal Höglund IDS, fungal Höglund IDS, and PLOC dataset, respectively. Furthermore, the close correlation between high-weighted GO terms and subcellular localizations suggests that our proposed method appropriately weights GO terms according to their relevance to the localizations. Copyright 2010 Elsevier Inc. All rights reserved.

  15. The review and results of different methods for facial recognition

    NASA Astrophysics Data System (ADS)

    Le, Yifan

    2017-09-01

    In recent years, facial recognition draws much attention due to its wide potential applications. As a unique technology in Biometric Identification, facial recognition represents a significant improvement since it could be operated without cooperation of people under detection. Hence, facial recognition will be taken into defense system, medical detection, human behavior understanding, etc. Several theories and methods have been established to make progress in facial recognition: (1) A novel two-stage facial landmark localization method is proposed which has more accurate facial localization effect under specific database; (2) A statistical face frontalization method is proposed which outperforms state-of-the-art methods for face landmark localization; (3) It proposes a general facial landmark detection algorithm to handle images with severe occlusion and images with large head poses; (4) There are three methods proposed on Face Alignment including shape augmented regression method, pose-indexed based multi-view method and a learning based method via regressing local binary features. The aim of this paper is to analyze previous work of different aspects in facial recognition, focusing on concrete method and performance under various databases. In addition, some improvement measures and suggestions in potential applications will be put forward.

  16. Context-Aware Local Binary Feature Learning for Face Recognition.

    PubMed

    Duan, Yueqi; Lu, Jiwen; Feng, Jianjiang; Zhou, Jie

    2018-05-01

    In this paper, we propose a context-aware local binary feature learning (CA-LBFL) method for face recognition. Unlike existing learning-based local face descriptors such as discriminant face descriptor (DFD) and compact binary face descriptor (CBFD) which learn each feature code individually, our CA-LBFL exploits the contextual information of adjacent bits by constraining the number of shifts from different binary bits, so that more robust information can be exploited for face representation. Given a face image, we first extract pixel difference vectors (PDV) in local patches, and learn a discriminative mapping in an unsupervised manner to project each pixel difference vector into a context-aware binary vector. Then, we perform clustering on the learned binary codes to construct a codebook, and extract a histogram feature for each face image with the learned codebook as the final representation. In order to exploit local information from different scales, we propose a context-aware local binary multi-scale feature learning (CA-LBMFL) method to jointly learn multiple projection matrices for face representation. To make the proposed methods applicable for heterogeneous face recognition, we present a coupled CA-LBFL (C-CA-LBFL) method and a coupled CA-LBMFL (C-CA-LBMFL) method to reduce the modality gap of corresponding heterogeneous faces in the feature level, respectively. Extensive experimental results on four widely used face datasets clearly show that our methods outperform most state-of-the-art face descriptors.

  17. Improving the local wavenumber method by automatic DEXP transformation

    NASA Astrophysics Data System (ADS)

    Abbas, Mahmoud Ahmed; Fedi, Maurizio; Florio, Giovanni

    2014-12-01

    In this paper we present a new method for source parameter estimation, based on the local wavenumber function. We make use of the stable properties of the Depth from EXtreme Points (DEXP) method, in which the depth to the source is determined at the extreme points of the field scaled with a power-law of the altitude. Thus the method results particularly suited to deal with local wavenumber of high-order, as it is able to overcome its known instability caused by the use of high-order derivatives. The DEXP transformation enjoys a relevant feature when applied to the local wavenumber function: the scaling-law is in fact independent of the structural index. So, differently from the DEXP transformation applied directly to potential fields, the Local Wavenumber DEXP transformation is fully automatic and may be implemented as a very fast imaging method, mapping every kind of source at the correct depth. Also the simultaneous presence of sources with different homogeneity degree can be easily and correctly treated. The method was applied to synthetic and real examples from Bulgaria and Italy and the results agree well with known information about the causative sources.

  18. Locally refined block-centred finite-difference groundwater models: Evaluation of parameter sensitivity and the consequences for inverse modelling

    USGS Publications Warehouse

    Mehl, S.; Hill, M.C.

    2002-01-01

    Models with local grid refinement, as often required in groundwater models, pose special problems for model calibration. This work investigates the calculation of sensitivities and the performance of regression methods using two existing and one new method of grid refinement. The existing local grid refinement methods considered are: (a) a variably spaced grid in which the grid spacing becomes smaller near the area of interest and larger where such detail is not needed, and (b) telescopic mesh refinement (TMR), which uses the hydraulic heads or fluxes of a regional model to provide the boundary conditions for a locally refined model. The new method has a feedback between the regional and local grids using shared nodes, and thereby, unlike the TMR methods, balances heads and fluxes at the interfacing boundary. Results for sensitivities are compared for the three methods and the effect of the accuracy of sensitivity calculations are evaluated by comparing inverse modelling results. For the cases tested, results indicate that the inaccuracies of the sensitivities calculated using the TMR approach can cause the inverse model to converge to an incorrect solution.

  19. Locally refined block-centered finite-difference groundwater models: Evaluation of parameter sensitivity and the consequences for inverse modelling and predictions

    USGS Publications Warehouse

    Mehl, S.; Hill, M.C.

    2002-01-01

    Models with local grid refinement, as often required in groundwater models, pose special problems for model calibration. This work investigates the calculation of sensitivities and performance of regression methods using two existing and one new method of grid refinement. The existing local grid refinement methods considered are (1) a variably spaced grid in which the grid spacing becomes smaller near the area of interest and larger where such detail is not needed and (2) telescopic mesh refinement (TMR), which uses the hydraulic heads or fluxes of a regional model to provide the boundary conditions for a locally refined model. The new method has a feedback between the regional and local grids using shared nodes, and thereby, unlike the TMR methods, balances heads and fluxes at the interfacing boundary. Results for sensitivities are compared for the three methods and the effect of the accuracy of sensitivity calculations are evaluated by comparing inverse modelling results. For the cases tested, results indicate that the inaccuracies of the sensitivities calculated using the TMR approach can cause the inverse model to converge to an incorrect solution.

  20. The Local Discontinuous Galerkin Method for Time-Dependent Convection-Diffusion Systems

    NASA Technical Reports Server (NTRS)

    Cockburn, Bernardo; Shu, Chi-Wang

    1997-01-01

    In this paper, we study the Local Discontinuous Galerkin methods for nonlinear, time-dependent convection-diffusion systems. These methods are an extension of the Runge-Kutta Discontinuous Galerkin methods for purely hyperbolic systems to convection-diffusion systems and share with those methods their high parallelizability, their high-order formal accuracy, and their easy handling of complicated geometries, for convection dominated problems. It is proven that for scalar equations, the Local Discontinuous Galerkin methods are L(sup 2)-stable in the nonlinear case. Moreover, in the linear case, it is shown that if polynomials of degree k are used, the methods are k-th order accurate for general triangulations; although this order of convergence is suboptimal, it is sharp for the LDG methods. Preliminary numerical examples displaying the performance of the method are shown.

  1. Locating Structural Centers: A Density-Based Clustering Method for Community Detection

    PubMed Central

    Liu, Gongshen; Li, Jianhua; Nees, Jan P.

    2017-01-01

    Uncovering underlying community structures in complex networks has received considerable attention because of its importance in understanding structural attributes and group characteristics of networks. The algorithmic identification of such structures is a significant challenge. Local expanding methods have proven to be efficient and effective in community detection, but most methods are sensitive to initial seeds and built-in parameters. In this paper, we present a local expansion method by density-based clustering, which aims to uncover the intrinsic network communities by locating the structural centers of communities based on a proposed structural centrality. The structural centrality takes into account local density of nodes and relative distance between nodes. The proposed algorithm expands a community from the structural center to the border with a single local search procedure. The local expanding procedure follows a heuristic strategy as allowing it to find complete community structures. Moreover, it can identify different node roles (cores and outliers) in communities by defining a border region. The experiments involve both on real-world and artificial networks, and give a comparison view to evaluate the proposed method. The result of these experiments shows that the proposed method performs more efficiently with a comparative clustering performance than current state of the art methods. PMID:28046030

  2. Peridynamic Multiscale Finite Element Methods

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Costa, Timothy; Bond, Stephen D.; Littlewood, David John

    The problem of computing quantum-accurate design-scale solutions to mechanics problems is rich with applications and serves as the background to modern multiscale science research. The prob- lem can be broken into component problems comprised of communicating across adjacent scales, which when strung together create a pipeline for information to travel from quantum scales to design scales. Traditionally, this involves connections between a) quantum electronic structure calculations and molecular dynamics and between b) molecular dynamics and local partial differ- ential equation models at the design scale. The second step, b), is particularly challenging since the appropriate scales of molecular dynamic andmore » local partial differential equation models do not overlap. The peridynamic model for continuum mechanics provides an advantage in this endeavor, as the basic equations of peridynamics are valid at a wide range of scales limiting from the classical partial differential equation models valid at the design scale to the scale of molecular dynamics. In this work we focus on the development of multiscale finite element methods for the peridynamic model, in an effort to create a mathematically consistent channel for microscale information to travel from the upper limits of the molecular dynamics scale to the design scale. In particular, we first develop a Nonlocal Multiscale Finite Element Method which solves the peridynamic model at multiple scales to include microscale information at the coarse-scale. We then consider a method that solves a fine-scale peridynamic model to build element-support basis functions for a coarse- scale local partial differential equation model, called the Mixed Locality Multiscale Finite Element Method. Given decades of research and development into finite element codes for the local partial differential equation models of continuum mechanics there is a strong desire to couple local and nonlocal models to leverage the speed and state of the art of local models with the flexibility and accuracy of the nonlocal peridynamic model. In the mixed locality method this coupling occurs across scales, so that the nonlocal model can be used to communicate material heterogeneity at scales inappropriate to local partial differential equation models. Additionally, the computational burden of the weak form of the peridynamic model is reduced dramatically by only requiring that the model be solved on local patches of the simulation domain which may be computed in parallel, taking advantage of the heterogeneous nature of next generation computing platforms. Addition- ally, we present a novel Galerkin framework, the 'Ambulant Galerkin Method', which represents a first step towards a unified mathematical analysis of local and nonlocal multiscale finite element methods, and whose future extension will allow the analysis of multiscale finite element methods that mix models across scales under certain assumptions of the consistency of those models.« less

  3. Geometric k-nearest neighbor estimation of entropy and mutual information

    NASA Astrophysics Data System (ADS)

    Lord, Warren M.; Sun, Jie; Bollt, Erik M.

    2018-03-01

    Nonparametric estimation of mutual information is used in a wide range of scientific problems to quantify dependence between variables. The k-nearest neighbor (knn) methods are consistent, and therefore expected to work well for a large sample size. These methods use geometrically regular local volume elements. This practice allows maximum localization of the volume elements, but can also induce a bias due to a poor description of the local geometry of the underlying probability measure. We introduce a new class of knn estimators that we call geometric knn estimators (g-knn), which use more complex local volume elements to better model the local geometry of the probability measures. As an example of this class of estimators, we develop a g-knn estimator of entropy and mutual information based on elliptical volume elements, capturing the local stretching and compression common to a wide range of dynamical system attractors. A series of numerical examples in which the thickness of the underlying distribution and the sample sizes are varied suggest that local geometry is a source of problems for knn methods such as the Kraskov-Stögbauer-Grassberger estimator when local geometric effects cannot be removed by global preprocessing of the data. The g-knn method performs well despite the manipulation of the local geometry. In addition, the examples suggest that the g-knn estimators can be of particular relevance to applications in which the system is large, but the data size is limited.

  4. Local dark matter and dark energy as estimated on a scale of ~1 Mpc in a self-consistent way

    NASA Astrophysics Data System (ADS)

    Chernin, A. D.; Teerikorpi, P.; Valtonen, M. J.; Dolgachev, V. P.; Domozhilova, L. M.; Byrd, G. G.

    2009-12-01

    Context: Dark energy was first detected from large distances on gigaparsec scales. If it is vacuum energy (or Einstein's Λ), it should also exist in very local space. Here we discuss its measurement on megaparsec scales of the Local Group. Aims: We combine the modified Kahn-Woltjer method for the Milky Way-M 31 binary and the HST observations of the expansion flow around the Local Group in order to study in a self-consistent way and simultaneously the local density of dark energy and the dark matter mass contained within the Local Group. Methods: A theoretical model is used that accounts for the dynamical effects of dark energy on a scale of ~1 Mpc. Results: The local dark energy density is put into the range 0.8-3.7ρv (ρv is the globally measured density), and the Local Group mass lies within 3.1-5.8×1012 M⊙. The lower limit of the local dark energy density, about 4/5× the global value, is determined by the natural binding condition for the group binary and the maximal zero-gravity radius. The near coincidence of two values measured with independent methods on scales differing by ~1000 times is remarkable. The mass ~4×1012 M⊙ and the local dark energy density ~ρv are also consistent with the expansion flow close to the Local Group, within the standard cosmological model. Conclusions: One should take into account the dark energy in dynamical mass estimation methods for galaxy groups, including the virial theorem. Our analysis gives new strong evidence in favor of Einstein's idea of the universal antigravity described by the cosmological constant.

  5. Embedded System Implementation of Sound Localization in Proximal Region

    NASA Astrophysics Data System (ADS)

    Iwanaga, Nobuyuki; Matsumura, Tomoya; Yoshida, Akihiro; Kobayashi, Wataru; Onoye, Takao

    A sound localization method in the proximal region is proposed, which is based on a low-cost 3D sound localization algorithm with the use of head-related transfer functions (HRTFs). The auditory parallax model is applied to the current algorithm so that more accurate HRTFs can be used for sound localization in the proximal region. In addition, head-shadowing effects based on rigid-sphere model are reproduced in the proximal region by means of a second-order IIR filter. A subjective listening test demonstrates the effectiveness of the proposed method. Embedded system implementation of the proposed method is also described claiming that the proposed method improves sound effects in the proximal region only with 5.1% increase of memory capacity and 8.3% of computational costs.

  6. Search-free license plate localization based on saliency and local variance estimation

    NASA Astrophysics Data System (ADS)

    Safaei, Amin; Tang, H. L.; Sanei, S.

    2015-02-01

    In recent years, the performance and accuracy of automatic license plate number recognition (ALPR) systems have greatly improved, however the increasing number of applications for such systems have made ALPR research more challenging than ever. The inherent computational complexity of search dependent algorithms remains a major problem for current ALPR systems. This paper proposes a novel search-free method of localization based on the estimation of saliency and local variance. Gabor functions are then used to validate the choice of candidate license plate. The algorithm was applied to three image datasets with different levels of complexity and the results compared with a number of benchmark methods, particularly in terms of speed. The proposed method outperforms the state of the art methods and can be used for real time applications.

  7. An Evaluation of Active Learning Causal Discovery Methods for Reverse-Engineering Local Causal Pathways of Gene Regulation

    PubMed Central

    Ma, Sisi; Kemmeren, Patrick; Aliferis, Constantin F.; Statnikov, Alexander

    2016-01-01

    Reverse-engineering of causal pathways that implicate diseases and vital cellular functions is a fundamental problem in biomedicine. Discovery of the local causal pathway of a target variable (that consists of its direct causes and direct effects) is essential for effective intervention and can facilitate accurate diagnosis and prognosis. Recent research has provided several active learning methods that can leverage passively observed high-throughput data to draft causal pathways and then refine the inferred relations with a limited number of experiments. The current study provides a comprehensive evaluation of the performance of active learning methods for local causal pathway discovery in real biological data. Specifically, 54 active learning methods/variants from 3 families of algorithms were applied for local causal pathways reconstruction of gene regulation for 5 transcription factors in S. cerevisiae. Four aspects of the methods’ performance were assessed, including adjacency discovery quality, edge orientation accuracy, complete pathway discovery quality, and experimental cost. The results of this study show that some methods provide significant performance benefits over others and therefore should be routinely used for local causal pathway discovery tasks. This study also demonstrates the feasibility of local causal pathway reconstruction in real biological systems with significant quality and low experimental cost. PMID:26939894

  8. Stochastic seismic inversion based on an improved local gradual deformation method

    NASA Astrophysics Data System (ADS)

    Yang, Xiuwei; Zhu, Peimin

    2017-12-01

    A new stochastic seismic inversion method based on the local gradual deformation method is proposed, which can incorporate seismic data, well data, geology and their spatial correlations into the inversion process. Geological information, such as sedimentary facies and structures, could provide significant a priori information to constrain an inversion and arrive at reasonable solutions. The local a priori conditional cumulative distributions at each node of model to be inverted are first established by indicator cokriging, which integrates well data as hard data and geological information as soft data. Probability field simulation is used to simulate different realizations consistent with the spatial correlations and local conditional cumulative distributions. The corresponding probability field is generated by the fast Fourier transform moving average method. Then, optimization is performed to match the seismic data via an improved local gradual deformation method. Two improved strategies are proposed to be suitable for seismic inversion. The first strategy is that we select and update local areas of bad fitting between synthetic seismic data and real seismic data. The second one is that we divide each seismic trace into several parts and obtain the optimal parameters for each part individually. The applications to a synthetic example and a real case study demonstrate that our approach can effectively find fine-scale acoustic impedance models and provide uncertainty estimations.

  9. Hybrid region merging method for segmentation of high-resolution remote sensing images

    NASA Astrophysics Data System (ADS)

    Zhang, Xueliang; Xiao, Pengfeng; Feng, Xuezhi; Wang, Jiangeng; Wang, Zuo

    2014-12-01

    Image segmentation remains a challenging problem for object-based image analysis. In this paper, a hybrid region merging (HRM) method is proposed to segment high-resolution remote sensing images. HRM integrates the advantages of global-oriented and local-oriented region merging strategies into a unified framework. The globally most-similar pair of regions is used to determine the starting point of a growing region, which provides an elegant way to avoid the problem of starting point assignment and to enhance the optimization ability for local-oriented region merging. During the region growing procedure, the merging iterations are constrained within the local vicinity, so that the segmentation is accelerated and can reflect the local context, as compared with the global-oriented method. A set of high-resolution remote sensing images is used to test the effectiveness of the HRM method, and three region-based remote sensing image segmentation methods are adopted for comparison, including the hierarchical stepwise optimization (HSWO) method, the local-mutual best region merging (LMM) method, and the multiresolution segmentation (MRS) method embedded in eCognition Developer software. Both the supervised evaluation and visual assessment show that HRM performs better than HSWO and LMM by combining both their advantages. The segmentation results of HRM and MRS are visually comparable, but HRM can describe objects as single regions better than MRS, and the supervised and unsupervised evaluation results further prove the superiority of HRM.

  10. A radial basis function Galerkin method for inhomogeneous nonlocal diffusion

    DOE PAGES

    Lehoucq, Richard B.; Rowe, Stephen T.

    2016-02-01

    We introduce a discretization for a nonlocal diffusion problem using a localized basis of radial basis functions. The stiffness matrix entries are assembled by a special quadrature routine unique to the localized basis. Combining the quadrature method with the localized basis produces a well-conditioned, sparse, symmetric positive definite stiffness matrix. We demonstrate that both the continuum and discrete problems are well-posed and present numerical results for the convergence behavior of the radial basis function method. As a result, we explore approximating the solution to anisotropic differential equations by solving anisotropic nonlocal integral equations using the radial basis function method.

  11. Perturbation Selection and Local Influence Analysis for Nonlinear Structural Equation Model

    ERIC Educational Resources Information Center

    Chen, Fei; Zhu, Hong-Tu; Lee, Sik-Yum

    2009-01-01

    Local influence analysis is an important statistical method for studying the sensitivity of a proposed model to model inputs. One of its important issues is related to the appropriate choice of a perturbation vector. In this paper, we develop a general method to select an appropriate perturbation vector and a second-order local influence measure…

  12. Slope stabilization guide for Minnesota local government engineers.

    DOT National Transportation Integrated Search

    2017-06-01

    This user guide provides simple, costeffective methods for stabilizing locally maintained slopes along roadways in Minnesota. Eight slope stabilization techniques are presented that local government engineers can undertake using locally available ...

  13. An Exact Model-Based Method for Near-Field Sources Localization with Bistatic MIMO System.

    PubMed

    Singh, Parth Raj; Wang, Yide; Chargé, Pascal

    2017-03-30

    In this paper, we propose an exact model-based method for near-field sources localization with a bistatic multiple input, multiple output (MIMO) radar system, and compare it with an approximated model-based method. The aim of this paper is to propose an efficient way to use the exact model of the received signals of near-field sources in order to eliminate the systematic error introduced by the use of approximated model in most existing near-field sources localization techniques. The proposed method uses parallel factor (PARAFAC) decomposition to deal with the exact model. Thanks to the exact model, the proposed method has better precision and resolution than the compared approximated model-based method. The simulation results show the performance of the proposed method.

  14. THE MURINE LOCAL LYMPH NODE ASSAY: AN ALTERNATIVE TEST METHOD FOR THE EVALUATION OF THE POTENTIAL FOR CHEMICALS TO ELICIT ALLERGIC CONTACT DERMATITIS

    EPA Science Inventory

    ABSTRACT
    The process that a new toxicology test method must undergo to attain acceptance and regulatory implementation may seem daunting. As the first test method to undergo Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) review, the local...

  15. Performance of local correlation methods for halogen bonding: The case of Br{sub 2}–(H{sub 2}O){sub n},n = 4,5 clusters and Br{sub 2}@5{sup 12}6{sup 2} clathrate cage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Batista-Romero, Fidel A.; Bernal-Uruchurtu, Margarita I.; Hernández-Lamoneda, Ramón, E-mail: ramon@uaem.mx

    The performance of local correlation methods is examined for the interactions present in clusters of bromine with water where the combined effect of hydrogen bonding (HB), halogen bonding (XB), and hydrogen-halogen (HX) interactions lead to many interesting properties. Local methods reproduce all the subtleties involved such as many-body effects and dispersion contributions provided that specific methodological steps are followed. Additionally, they predict optimized geometries that are nearly free of basis set superposition error that lead to improved estimates of spectroscopic properties. Taking advantage of the local correlation energy partitioning scheme, we compare the different interaction environments present in small clustersmore » and those inside the 5{sup 12}6{sup 2} clathrate cage. This analysis allows a clear identification of the reasons supporting the use of local methods for large systems where non-covalent interactions play a key role.« less

  16. Hierarchical ensemble of global and local classifiers for face recognition.

    PubMed

    Su, Yu; Shan, Shiguang; Chen, Xilin; Gao, Wen

    2009-08-01

    In the literature of psychophysics and neurophysiology, many studies have shown that both global and local features are crucial for face representation and recognition. This paper proposes a novel face recognition method which exploits both global and local discriminative features. In this method, global features are extracted from the whole face images by keeping the low-frequency coefficients of Fourier transform, which we believe encodes the holistic facial information, such as facial contour. For local feature extraction, Gabor wavelets are exploited considering their biological relevance. After that, Fisher's linear discriminant (FLD) is separately applied to the global Fourier features and each local patch of Gabor features. Thus, multiple FLD classifiers are obtained, each embodying different facial evidences for face recognition. Finally, all these classifiers are combined to form a hierarchical ensemble classifier. We evaluate the proposed method using two large-scale face databases: FERET and FRGC version 2.0. Experiments show that the results of our method are impressively better than the best known results with the same evaluation protocol.

  17. Utility of Vibratory Stimulation for Reducing Intraoral Injection Pain.

    PubMed

    Erdogan, Ozgur; Sinsawat, Anatachai; Pawa, Sudeep; Rintanalert, Duangtawan; Vuddhakanok, Suchada

    2018-01-01

    Intraoral local anesthesia injection is often perceived as a painful and anxiety-causing dental procedure. Vibration stimulus is one of the nonpharmacologic methods used to reduce unwanted sensations of local anesthesia injection. This clinical study evaluated the effectiveness of a recently introduced vibratory stimulation device in intraoral local anesthesia administration. Thirty-two subjects underwent 2 maxillary local anesthesia injections in 2 different sessions: 1 with conventional techniques and 1 with the aid of a vibratory stimulation device (DentalVibe). The pain levels were evaluated with a visual analog scale and the Wong-Baker FACES Pain Rating Scale. The subjects were asked to choose the preferred method for future injections. The data were evaluated statistically. There were no significant differences between the 2 injection methods with regard to either pain evaluation method. The preference of the subjects regarding future injection technique was evenly distributed between the groups. The vibratory stimulation device used in this study did not provide any reduction in pain level associated with maxillary infiltration local anesthesia administration.

  18. An evaluation of methods for estimating the number of local optima in combinatorial optimization problems.

    PubMed

    Hernando, Leticia; Mendiburu, Alexander; Lozano, Jose A

    2013-01-01

    The solution of many combinatorial optimization problems is carried out by metaheuristics, which generally make use of local search algorithms. These algorithms use some kind of neighborhood structure over the search space. The performance of the algorithms strongly depends on the properties that the neighborhood imposes on the search space. One of these properties is the number of local optima. Given an instance of a combinatorial optimization problem and a neighborhood, the estimation of the number of local optima can help not only to measure the complexity of the instance, but also to choose the most convenient neighborhood to solve it. In this paper we review and evaluate several methods to estimate the number of local optima in combinatorial optimization problems. The methods reviewed not only come from the combinatorial optimization literature, but also from the statistical literature. A thorough evaluation in synthetic as well as real problems is given. We conclude by providing recommendations of methods for several scenarios.

  19. A Local Agreement Pattern Measure Based on Hazard Functions for Survival Outcomes

    PubMed Central

    Dai, Tian; Guo, Ying; Peng, Limin; Manatunga, Amita K.

    2017-01-01

    Summary Assessing agreement is often of interest in biomedical and clinical research when measurements are obtained on the same subjects by different raters or methods. Most classical agreement methods have been focused on global summary statistics, which cannot be used to describe various local agreement patterns. The objective of this work is to study the local agreement pattern between two continuous measurements subject to censoring. In this paper, we propose a new agreement measure based on bivariate hazard functions to characterize the local agreement pattern between two correlated survival outcomes. The proposed measure naturally accommodates censored observations, fully captures the dependence structure between bivariate survival times and provides detailed information on how the strength of agreement evolves over time. We develop a nonparametric estimation method for the proposed local agreement pattern measure and study theoretical properties including strong consistency and asymptotical normality. We then evaluate the performance of the estimator through simulation studies and illustrate the method using a prostate cancer data example. PMID:28724196

  20. A local agreement pattern measure based on hazard functions for survival outcomes.

    PubMed

    Dai, Tian; Guo, Ying; Peng, Limin; Manatunga, Amita K

    2018-03-01

    Assessing agreement is often of interest in biomedical and clinical research when measurements are obtained on the same subjects by different raters or methods. Most classical agreement methods have been focused on global summary statistics, which cannot be used to describe various local agreement patterns. The objective of this work is to study the local agreement pattern between two continuous measurements subject to censoring. In this article, we propose a new agreement measure based on bivariate hazard functions to characterize the local agreement pattern between two correlated survival outcomes. The proposed measure naturally accommodates censored observations, fully captures the dependence structure between bivariate survival times and provides detailed information on how the strength of agreement evolves over time. We develop a nonparametric estimation method for the proposed local agreement pattern measure and study theoretical properties including strong consistency and asymptotical normality. We then evaluate the performance of the estimator through simulation studies and illustrate the method using a prostate cancer data example. © 2017, The International Biometric Society.

  1. Complex background suppression using global-local registration strategy for the detection of small-moving target on moving platform

    NASA Astrophysics Data System (ADS)

    Zou, Tianhao; Zuo, Zhengrong

    2018-02-01

    Target detection is a very important and basic problem of computer vision and image processing. The most often case we meet in real world is a detection task for a moving-small target on moving platform. The commonly used methods, such as Registration-based suppression, can hardly achieve a desired result. To crack this hard nut, we introduce a Global-local registration based suppression method. Differ from the traditional ones, the proposed Global-local Registration Strategy consider both the global consistency and the local diversity of the background, obtain a better performance than normal background suppression methods. In this paper, we first discussed the features about the small-moving target detection on unstable platform. Then we introduced a new strategy and conducted an experiment to confirm its noisy stability. In the end, we confirmed the background suppression method based on global-local registration strategy has a better perform in moving target detection on moving platform.

  2. The influence of local policy on contraceptive provision and use in three locales in the Philippines.

    PubMed

    Lee, Romeo B; Nacionales, Lourdes P; Pedroso, Luis

    2009-11-01

    The Philippines has a family planning programme, but modern contraceptive prevalence has been moderate. Among low-income women, fewer are using modern methods, resulting in a fertility rate among them of 5.9. This limited use is due to lack of consistent national and local government support for modern methods because of religious opposition. Following devolution of responsibility for health services to local government in 1991, three local leaders - in Laguna Province and the cities of Manila and Puerto Princesa - passed anti-modern contraceptive policies. This paper analyses the status and impact of these policies, using information from interviews with local government officials and family planning officers, published data and studies, and accounts in national newspapers. In Laguna Province and Puerto Princesa, the policies were ineffectually implemented or short-lived. The strictly-enforced Manila law, however, has severely disrupted the city's provision of free contraception to and method use by low-income women. The great majority of Filipinos (89%) approve of modern contraceptives. There is an urgent need to improve low-income women's access to modern contraceptives through itinerant and community-based distribution, especially in poor neighbourhoods in Manila, but also throughout the country. Strategies for increasing local government support for and provision of modern methods are also needed.

  3. Local multifractal detrended fluctuation analysis for non-stationary image's texture segmentation

    NASA Astrophysics Data System (ADS)

    Wang, Fang; Li, Zong-shou; Li, Jin-wei

    2014-12-01

    Feature extraction plays a great important role in image processing and pattern recognition. As a power tool, multifractal theory is recently employed for this job. However, traditional multifractal methods are proposed to analyze the objects with stationary measure and cannot for non-stationary measure. The works of this paper is twofold. First, the definition of stationary image and 2D image feature detection methods are proposed. Second, a novel feature extraction scheme for non-stationary image is proposed by local multifractal detrended fluctuation analysis (Local MF-DFA), which is based on 2D MF-DFA. A set of new multifractal descriptors, called local generalized Hurst exponent (Lhq) is defined to characterize the local scaling properties of textures. To test the proposed method, both the novel texture descriptor and other two multifractal indicators, namely, local Hölder coefficients based on capacity measure and multifractal dimension Dq based on multifractal differential box-counting (MDBC) method, are compared in segmentation experiments. The first experiment indicates that the segmentation results obtained by the proposed Lhq are better than the MDBC-based Dq slightly and superior to the local Hölder coefficients significantly. The results in the second experiment demonstrate that the Lhq can distinguish the texture images more effectively and provide more robust segmentations than the MDBC-based Dq significantly.

  4. 3-D Localization Method for a Magnetically Actuated Soft Capsule Endoscope and Its Applications

    PubMed Central

    Yim, Sehyuk; Sitti, Metin

    2014-01-01

    In this paper, we present a 3-D localization method for a magnetically actuated soft capsule endoscope (MASCE). The proposed localization scheme consists of three steps. First, MASCE is oriented to be coaxially aligned with an external permanent magnet (EPM). Second, MASCE is axially contracted by the enhanced magnetic attraction of the approaching EPM. Third, MASCE recovers its initial shape by the retracting EPM as the magnetic attraction weakens. The combination of the estimated direction in the coaxial alignment step and the estimated distance in the shape deformation (recovery) step provides the position of MASCE in 3-D. It is experimentally shown that the proposed localization method could provide 2.0–3.7 mm of distance error in 3-D. This study also introduces two new applications of the proposed localization method. First, based on the trace of contact points between the MASCE and the surface of the stomach, the 3-D geometrical model of a synthetic stomach was reconstructed. Next, the relative tissue compliance at each local contact point in the stomach was characterized by measuring the local tissue deformation at each point due to the preloading force. Finally, the characterized relative tissue compliance parameter was mapped onto the geometrical model of the stomach toward future use in disease diagnosis. PMID:25383064

  5. Automatic localization of cochlear implant electrodes in CTs with a limited intensity range

    NASA Astrophysics Data System (ADS)

    Zhao, Yiyuan; Dawant, Benoit M.; Noble, Jack H.

    2017-02-01

    Cochlear implants (CIs) are neural prosthetics for treating severe-to-profound hearing loss. Our group has developed an image-guided cochlear implant programming (IGCIP) system that uses image analysis techniques to recommend patientspecific CI processor settings to improve hearing outcomes. One crucial step in IGCIP is the localization of CI electrodes in post-implantation CTs. Manual localization of electrodes requires time and expertise. To automate this process, our group has proposed automatic techniques that have been validated on CTs acquired with scanners that produce images with an extended range of intensity values. However, there are many clinical CTs acquired with a limited intensity range. This limitation complicates the electrode localization process. In this work, we present a pre-processing step for CTs with a limited intensity range and extend the methods we proposed for full intensity range CTs to localize CI electrodes in CTs with limited intensity range. We evaluate our method on CTs of 20 subjects implanted with CI arrays produced by different manufacturers. Our method achieves a mean localization error of 0.21mm. This indicates our method is robust for automatic localization of CI electrodes in different types of CTs, which represents a crucial step for translating IGCIP from research laboratory to clinical use.

  6. Local Feature Selection for Data Classification.

    PubMed

    Armanfard, Narges; Reilly, James P; Komeili, Majid

    2016-06-01

    Typical feature selection methods choose an optimal global feature subset that is applied over all regions of the sample space. In contrast, in this paper we propose a novel localized feature selection (LFS) approach whereby each region of the sample space is associated with its own distinct optimized feature set, which may vary both in membership and size across the sample space. This allows the feature set to optimally adapt to local variations in the sample space. An associated method for measuring the similarities of a query datum to each of the respective classes is also proposed. The proposed method makes no assumptions about the underlying structure of the samples; hence the method is insensitive to the distribution of the data over the sample space. The method is efficiently formulated as a linear programming optimization problem. Furthermore, we demonstrate the method is robust against the over-fitting problem. Experimental results on eleven synthetic and real-world data sets demonstrate the viability of the formulation and the effectiveness of the proposed algorithm. In addition we show several examples where localized feature selection produces better results than a global feature selection method.

  7. Small Imaging Depth LIDAR and DCNN-Based Localization for Automated Guided Vehicle †

    PubMed Central

    Ito, Seigo; Hiratsuka, Shigeyoshi; Ohta, Mitsuhiko; Matsubara, Hiroyuki; Ogawa, Masaru

    2018-01-01

    We present our third prototype sensor and a localization method for Automated Guided Vehicles (AGVs), for which small imaging LIght Detection and Ranging (LIDAR) and fusion-based localization are fundamentally important. Our small imaging LIDAR, named the Single-Photon Avalanche Diode (SPAD) LIDAR, uses a time-of-flight method and SPAD arrays. A SPAD is a highly sensitive photodetector capable of detecting at the single-photon level, and the SPAD LIDAR has two SPAD arrays on the same chip for detection of laser light and environmental light. Therefore, the SPAD LIDAR simultaneously outputs range image data and monocular image data with the same coordinate system and does not require external calibration among outputs. As AGVs travel both indoors and outdoors with vibration, this calibration-less structure is particularly useful for AGV applications. We also introduce a fusion-based localization method, named SPAD DCNN, which uses the SPAD LIDAR and employs a Deep Convolutional Neural Network (DCNN). SPAD DCNN can fuse the outputs of the SPAD LIDAR: range image data, monocular image data and peak intensity image data. The SPAD DCNN has two outputs: the regression result of the position of the SPAD LIDAR and the classification result of the existence of a target to be approached. Our third prototype sensor and the localization method are evaluated in an indoor environment by assuming various AGV trajectories. The results show that the sensor and localization method improve the localization accuracy. PMID:29320434

  8. Small Imaging Depth LIDAR and DCNN-Based Localization for Automated Guided Vehicle.

    PubMed

    Ito, Seigo; Hiratsuka, Shigeyoshi; Ohta, Mitsuhiko; Matsubara, Hiroyuki; Ogawa, Masaru

    2018-01-10

    We present our third prototype sensor and a localization method for Automated Guided Vehicles (AGVs), for which small imaging LIght Detection and Ranging (LIDAR) and fusion-based localization are fundamentally important. Our small imaging LIDAR, named the Single-Photon Avalanche Diode (SPAD) LIDAR, uses a time-of-flight method and SPAD arrays. A SPAD is a highly sensitive photodetector capable of detecting at the single-photon level, and the SPAD LIDAR has two SPAD arrays on the same chip for detection of laser light and environmental light. Therefore, the SPAD LIDAR simultaneously outputs range image data and monocular image data with the same coordinate system and does not require external calibration among outputs. As AGVs travel both indoors and outdoors with vibration, this calibration-less structure is particularly useful for AGV applications. We also introduce a fusion-based localization method, named SPAD DCNN, which uses the SPAD LIDAR and employs a Deep Convolutional Neural Network (DCNN). SPAD DCNN can fuse the outputs of the SPAD LIDAR: range image data, monocular image data and peak intensity image data. The SPAD DCNN has two outputs: the regression result of the position of the SPAD LIDAR and the classification result of the existence of a target to be approached. Our third prototype sensor and the localization method are evaluated in an indoor environment by assuming various AGV trajectories. The results show that the sensor and localization method improve the localization accuracy.

  9. The contribution of local and transport processes to phytoplankton biomass variability over different timescales in the Upper James River, Virginia

    NASA Astrophysics Data System (ADS)

    Qin, Qubin; Shen, Jian

    2017-09-01

    Although both local processes (photosynthesis, respiration, grazing, and settling), and transport processes (advective transport and diffusive transport) significantly affect local phytoplankton dynamics, it is difficult to separate their contributions and to investigate the relative importance of each process to the local variability of phytoplankton biomass over different timescales. A method of using the transport rate is introduced to quantify the contribution of transport processes. By combining the time-varying transport rate and high-frequency observed chlorophyll a data, we can explicitly examine the impact of local and transport processes on phytoplankton biomass over a range of timescales from hourly to annually. For the Upper James River, results show that the relative importance of local and transport processes differs on different timescales. Local processes dominate phytoplankton variability on daily to weekly timescales, whereas the contribution of transport processes increases on seasonal to annual timescales and reaches equilibrium with local processes. With the use of the transport rate and high-frequency chlorophyll a data, a method similar to the open water oxygen method for metabolism is also presented to estimate phytoplankton primary production.

  10. The Green’s functions for peridynamic non-local diffusion

    PubMed Central

    Wang, L. J.; Xu, J. F.

    2016-01-01

    In this work, we develop the Green’s function method for the solution of the peridynamic non-local diffusion model in which the spatial gradient of the generalized potential in the classical theory is replaced by an integral of a generalized response function in a horizon. We first show that the general solutions of the peridynamic non-local diffusion model can be expressed as functionals of the corresponding Green’s functions for point sources, along with volume constraints for non-local diffusion. Then, we obtain the Green’s functions by the Fourier transform method for unsteady and steady diffusions in infinite domains. We also demonstrate that the peridynamic non-local solutions converge to the classical differential solutions when the non-local length approaches zero. Finally, the peridynamic analytical solutions are applied to an infinite plate heated by a Gauss source, and the predicted variations of temperature are compared with the classical local solutions. The peridynamic non-local diffusion model predicts a lower rate of variation of the field quantities than that of the classical theory, which is consistent with experimental observations. The developed method is applicable to general diffusion-type problems. PMID:27713658

  11. Fire Source Localization Based on Distributed Temperature Sensing by a Dual-Line Optical Fiber System.

    PubMed

    Sun, Miao; Tang, Yuquan; Yang, Shuang; Li, Jun; Sigrist, Markus W; Dong, Fengzhong

    2016-06-06

    We propose a method for localizing a fire source using an optical fiber distributed temperature sensor system. A section of two parallel optical fibers employed as the sensing element is installed near the ceiling of a closed room in which the fire source is located. By measuring the temperature of hot air flows, the problem of three-dimensional fire source localization is transformed to two dimensions. The method of the source location is verified with experiments using burning alcohol as fire source, and it is demonstrated that the method represents a robust and reliable technique for localizing a fire source also for long sensing ranges.

  12. An Efficient Estimator for Moving Target Localization Using Multi-Station Dual-Frequency Radars.

    PubMed

    Huang, Jiyan; Zhang, Ying; Luo, Shan

    2017-12-15

    Localization of a moving target in a dual-frequency radars system has now gained considerable attention. The noncoherent localization approach based on a least squares (LS) estimator has been addressed in the literature. Compared with the LS method, a novel localization method based on a two-step weighted least squares estimator is proposed to increase positioning accuracy for a multi-station dual-frequency radars system in this paper. The effects of signal noise ratio and the number of samples on the performance of range estimation are also analyzed in the paper. Furthermore, both the theoretical variance and Cramer-Rao lower bound (CRLB) are derived. The simulation results verified the proposed method.

  13. An Efficient Estimator for Moving Target Localization Using Multi-Station Dual-Frequency Radars

    PubMed Central

    Zhang, Ying; Luo, Shan

    2017-01-01

    Localization of a moving target in a dual-frequency radars system has now gained considerable attention. The noncoherent localization approach based on a least squares (LS) estimator has been addressed in the literature. Compared with the LS method, a novel localization method based on a two-step weighted least squares estimator is proposed to increase positioning accuracy for a multi-station dual-frequency radars system in this paper. The effects of signal noise ratio and the number of samples on the performance of range estimation are also analyzed in the paper. Furthermore, both the theoretical variance and Cramer–Rao lower bound (CRLB) are derived. The simulation results verified the proposed method. PMID:29244727

  14. Collaborative localization in wireless sensor networks via pattern recognition in radio irregularity using omnidirectional antennas.

    PubMed

    Jiang, Joe-Air; Chuang, Cheng-Long; Lin, Tzu-Shiang; Chen, Chia-Pang; Hung, Chih-Hung; Wang, Jiing-Yi; Liu, Chang-Wang; Lai, Tzu-Yun

    2010-01-01

    In recent years, various received signal strength (RSS)-based localization estimation approaches for wireless sensor networks (WSNs) have been proposed. RSS-based localization is regarded as a low-cost solution for many location-aware applications in WSNs. In previous studies, the radiation patterns of all sensor nodes are assumed to be spherical, which is an oversimplification of the radio propagation model in practical applications. In this study, we present an RSS-based cooperative localization method that estimates unknown coordinates of sensor nodes in a network. Arrangement of two external low-cost omnidirectional dipole antennas is developed by using the distance-power gradient model. A modified robust regression is also proposed to determine the relative azimuth and distance between a sensor node and a fixed reference node. In addition, a cooperative localization scheme that incorporates estimations from multiple fixed reference nodes is presented to improve the accuracy of the localization. The proposed method is tested via computer-based analysis and field test. Experimental results demonstrate that the proposed low-cost method is a useful solution for localizing sensor nodes in unknown or changing environments.

  15. The magnetic particle in a box: Analytic and micromagnetic analysis of probe-localized spin wave modes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Adur, Rohan, E-mail: adur@physics.osu.edu; Du, Chunhui; Manuilov, Sergei A.

    2015-05-07

    The dipole field from a probe magnet can be used to localize a discrete spectrum of standing spin wave modes in a continuous ferromagnetic thin film without lithographic modification to the film. Obtaining the resonance field for a localized mode is not trivial due to the effect of the confined and inhomogeneous magnetization precession. We compare the results of micromagnetic and analytic methods to find the resonance field of localized modes in a ferromagnetic thin film, and investigate the accuracy of these methods by comparing with a numerical minimization technique that assumes Bessel function modes with pinned boundary conditions. Wemore » find that the micromagnetic technique, while computationally more intensive, reveals that the true magnetization profiles of localized modes are similar to Bessel functions with gradually decaying dynamic magnetization at the mode edges. We also find that an analytic solution, which is simple to implement and computationally much faster than other methods, accurately describes the resonance field of localized modes when exchange fields are negligible, and demonstrating the accessibility of localized mode analysis.« less

  16. How Dangerous Can Localized Corrosion Be? An Experiment that Studies Its Effects.

    ERIC Educational Resources Information Center

    Celdran, R.; Gonzalo, P.

    1988-01-01

    Considers three common cases of localized corrosion of metals: pitting, crevice, and stress corrosion. Provides experimental methods for studying all three methods. Includes a discussion of expected results. (ML)

  17. A global/local analysis method for treating details in structural design

    NASA Technical Reports Server (NTRS)

    Aminpour, Mohammad A.; Mccleary, Susan L.; Ransom, Jonathan B.

    1993-01-01

    A method for analyzing global/local behavior of plate and shell structures is described. In this approach, a detailed finite element model of the local region is incorporated within a coarser global finite element model. The local model need not be nodally compatible (i.e., need not have a one-to-one nodal correspondence) with the global model at their common boundary; therefore, the two models may be constructed independently. The nodal incompatibility of the models is accounted for by introducing appropriate constraint conditions into the potential energy in a hybrid variational formulation. The primary advantage of this method is that the need for transition modeling between global and local models is eliminated. Eliminating transition modeling has two benefits. First, modeling efforts are reduced since tedious and complex transitioning need not be performed. Second, errors due to the mesh distortion, often unavoidable in mesh transitioning, are minimized by avoiding distorted elements beyond what is needed to represent the geometry of the component. The method is applied reduced to a plate loaded in tension and transverse bending. The plate has a central hole, and various hole sixes and shapes are studied. The method is also applied to a composite laminated fuselage panel with a crack emanating from a window in the panel. While this method is applied herein to global/local problems, it is also applicable to the coupled analysis of independently modeled components as well as adaptive refinement.

  18. The Health Role of Local Area Coordinators in Scotland: A Mixed Methods Study

    ERIC Educational Resources Information Center

    Brown, Michael; Karatzias, Thanos; O'Leary, Lisa

    2013-01-01

    The study set out to explore whether local area coordinators (LACs) and their managers view the health role of LACs as an essential component of their work and identify the health-related activities undertaken by LACs in Scotland. A mixed methods cross-sectional phenomenological study involving local authority service managers (n = 25) and LACs (n…

  19. An off-lattice, self-learning kinetic Monte Carlo method using local environments.

    PubMed

    Konwar, Dhrubajit; Bhute, Vijesh J; Chatterjee, Abhijit

    2011-11-07

    We present a method called local environment kinetic Monte Carlo (LE-KMC) method for efficiently performing off-lattice, self-learning kinetic Monte Carlo (KMC) simulations of activated processes in material systems. Like other off-lattice KMC schemes, new atomic processes can be found on-the-fly in LE-KMC. However, a unique feature of LE-KMC is that as long as the assumption that all processes and rates depend only on the local environment is satisfied, LE-KMC provides a general algorithm for (i) unambiguously describing a process in terms of its local atomic environments, (ii) storing new processes and environments in a catalog for later use with standard KMC, and (iii) updating the system based on the local information once a process has been selected for a KMC move. Search, classification, storage and retrieval steps needed while employing local environments and processes in the LE-KMC method are discussed. The advantages and computational cost of LE-KMC are discussed. We assess the performance of the LE-KMC algorithm by considering test systems involving diffusion in a submonolayer Ag and Ag-Cu alloy films on Ag(001) surface.

  20. Crowd-sourced pictures geo-localization method based on street view images and 3D reconstruction

    NASA Astrophysics Data System (ADS)

    Cheng, Liang; Yuan, Yi; Xia, Nan; Chen, Song; Chen, Yanming; Yang, Kang; Ma, Lei; Li, Manchun

    2018-07-01

    People are increasingly becoming accustomed to taking photos of everyday life in modern cities and uploading them on major photo-sharing social media sites. These sites contain numerous pictures, but some have incomplete or blurred location information. The geo-localization of crowd-sourced pictures enriches the information contained therein, and is applicable to activities such as urban construction, urban landscape analysis, and crime tracking. However, geo-localization faces huge technical challenges. This paper proposes a method for large-scale geo-localization of crowd-sourced pictures. Our approach uses structured, organized Street View images as a reference dataset and employs a three-step strategy of coarse geo-localization by image retrieval, selecting reliable matches by image registration, and fine geo-localization by 3D reconstruction to attach geographic tags to pictures from unidentified sources. In study area, 3D reconstruction based on close-range photogrammetry is used to restore the 3D geographical information of the crowd-sourced pictures, resulting in the proposed method improving the median error from 256.7 m to 69.0 m, and the percentage of the geo-localized query pictures under a 50 m error from 17.2% to 43.2% compared with the previous method. Another discovery using the proposed method is that, in respect of the causes of reconstruction error, closer distances from the cameras to the main objects in query pictures tend to produce lower errors and the component of error parallel to the road makes a more significant contribution to the Total Error. The proposed method is not limited to small areas, and could be expanded to cities and larger areas owing to its flexible parameters.

  1. Unsupervised Segmentation of Head Tissues from Multi-modal MR Images for EEG Source Localization.

    PubMed

    Mahmood, Qaiser; Chodorowski, Artur; Mehnert, Andrew; Gellermann, Johanna; Persson, Mikael

    2015-08-01

    In this paper, we present and evaluate an automatic unsupervised segmentation method, hierarchical segmentation approach (HSA)-Bayesian-based adaptive mean shift (BAMS), for use in the construction of a patient-specific head conductivity model for electroencephalography (EEG) source localization. It is based on a HSA and BAMS for segmenting the tissues from multi-modal magnetic resonance (MR) head images. The evaluation of the proposed method was done both directly in terms of segmentation accuracy and indirectly in terms of source localization accuracy. The direct evaluation was performed relative to a commonly used reference method brain extraction tool (BET)-FMRIB's automated segmentation tool (FAST) and four variants of the HSA using both synthetic data and real data from ten subjects. The synthetic data includes multiple realizations of four different noise levels and several realizations of typical noise with a 20% bias field level. The Dice index and Hausdorff distance were used to measure the segmentation accuracy. The indirect evaluation was performed relative to the reference method BET-FAST using synthetic two-dimensional (2D) multimodal magnetic resonance (MR) data with 3% noise and synthetic EEG (generated for a prescribed source). The source localization accuracy was determined in terms of localization error and relative error of potential. The experimental results demonstrate the efficacy of HSA-BAMS, its robustness to noise and the bias field, and that it provides better segmentation accuracy than the reference method and variants of the HSA. They also show that it leads to a more accurate localization accuracy than the commonly used reference method and suggest that it has potential as a surrogate for expert manual segmentation for the EEG source localization problem.

  2. A high-resolution computational localization method for transcranial magnetic stimulation mapping.

    PubMed

    Aonuma, Shinta; Gomez-Tames, Jose; Laakso, Ilkka; Hirata, Akimasa; Takakura, Tomokazu; Tamura, Manabu; Muragaki, Yoshihiro

    2018-05-15

    Transcranial magnetic stimulation (TMS) is used for the mapping of brain motor functions. The complexity of the brain deters determining the exact localization of the stimulation site using simplified methods (e.g., the region below the center of the TMS coil) or conventional computational approaches. This study aimed to present a high-precision localization method for a specific motor area by synthesizing computed non-uniform current distributions in the brain for multiple sessions of TMS. Peritumoral mapping by TMS was conducted on patients who had intra-axial brain neoplasms located within or close to the motor speech area. The electric field induced by TMS was computed using realistic head models constructed from magnetic resonance images of patients. A post-processing method was implemented to determine a TMS hotspot by combining the computed electric fields for the coil orientations and positions that delivered high motor-evoked potentials during peritumoral mapping. The method was compared to the stimulation site localized via intraoperative direct brain stimulation and navigated TMS. Four main results were obtained: 1) the dependence of the computed hotspot area on the number of peritumoral measurements was evaluated; 2) the estimated localization of the hand motor area in eight non-affected hemispheres was in good agreement with the position of a so-called "hand-knob"; 3) the estimated hotspot areas were not sensitive to variations in tissue conductivity; and 4) the hand motor areas estimated by this proposal and direct electric stimulation (DES) were in good agreement in the ipsilateral hemisphere of four glioma patients. The TMS localization method was validated by well-known positions of the "hand-knob" in brains for the non-affected hemisphere, and by a hotspot localized via DES during awake craniotomy for the tumor-containing hemisphere. Copyright © 2018 Elsevier Inc. All rights reserved.

  3. A coverage and slicing dependencies analysis for seeking software security defects.

    PubMed

    He, Hui; Zhang, Dongyan; Liu, Min; Zhang, Weizhe; Gao, Dongmin

    2014-01-01

    Software security defects have a serious impact on the software quality and reliability. It is a major hidden danger for the operation of a system that a software system has some security flaws. When the scale of the software increases, its vulnerability has becoming much more difficult to find out. Once these vulnerabilities are exploited, it may lead to great loss. In this situation, the concept of Software Assurance is carried out by some experts. And the automated fault localization technique is a part of the research of Software Assurance. Currently, automated fault localization method includes coverage based fault localization (CBFL) and program slicing. Both of the methods have their own location advantages and defects. In this paper, we have put forward a new method, named Reverse Data Dependence Analysis Model, which integrates the two methods by analyzing the program structure. On this basis, we finally proposed a new automated fault localization method. This method not only is automation lossless but also changes the basic location unit into single sentence, which makes the location effect more accurate. Through several experiments, we proved that our method is more effective. Furthermore, we analyzed the effectiveness among these existing methods and different faults.

  4. Localization of small arms fire using acoustic measurements of muzzle blast and/or ballistic shock wave arrivals.

    PubMed

    Lo, Kam W; Ferguson, Brian G

    2012-11-01

    The accurate localization of small arms fire using fixed acoustic sensors is considered. First, the conventional wavefront-curvature passive ranging method, which requires only differential time-of-arrival (DTOA) measurements of the muzzle blast wave to estimate the source position, is modified to account for sensor positions that are not strictly collinear (bowed array). Second, an existing single-sensor-node ballistic model-based localization method, which requires both DTOA and differential angle-of-arrival (DAOA) measurements of the muzzle blast wave and ballistic shock wave, is improved by replacing the basic external ballistics model (which describes the bullet's deceleration along its trajectory) with a more rigorous model and replacing the look-up table ranging procedure with a nonlinear (or polynomial) equation-based ranging procedure. Third, a new multiple-sensor-node ballistic model-based localization method, which requires only DTOA measurements of the ballistic shock wave to localize the point of fire, is formulated. The first method is applicable to situations when only the muzzle blast wave is received, whereas the third method applies when only the ballistic shock wave is received. The effectiveness of each of these methods is verified using an extensive set of real data recorded during a 7 day field experiment.

  5. Component-based subspace linear discriminant analysis method for face recognition with one training sample

    NASA Astrophysics Data System (ADS)

    Huang, Jian; Yuen, Pong C.; Chen, Wen-Sheng; Lai, J. H.

    2005-05-01

    Many face recognition algorithms/systems have been developed in the last decade and excellent performances have also been reported when there is a sufficient number of representative training samples. In many real-life applications such as passport identification, only one well-controlled frontal sample image is available for training. Under this situation, the performance of existing algorithms will degrade dramatically or may not even be implemented. We propose a component-based linear discriminant analysis (LDA) method to solve the one training sample problem. The basic idea of the proposed method is to construct local facial feature component bunches by moving each local feature region in four directions. In this way, we not only generate more samples with lower dimension than the original image, but also consider the face detection localization error while training. After that, we propose a subspace LDA method, which is tailor-made for a small number of training samples, for the local feature projection to maximize the discrimination power. Theoretical analysis and experiment results show that our proposed subspace LDA is efficient and overcomes the limitations in existing LDA methods. Finally, we combine the contributions of each local component bunch with a weighted combination scheme to draw the recognition decision. A FERET database is used for evaluating the proposed method and results are encouraging.

  6. Integrated analysis on static/dynamic aeroelasticity of curved panels based on a modified local piston theory

    NASA Astrophysics Data System (ADS)

    Yang, Zhichun; Zhou, Jian; Gu, Yingsong

    2014-10-01

    A flow field modified local piston theory, which is applied to the integrated analysis on static/dynamic aeroelastic behaviors of curved panels, is proposed in this paper. The local flow field parameters used in the modification are obtained by CFD technique which has the advantage to simulate the steady flow field accurately. This flow field modified local piston theory for aerodynamic loading is applied to the analysis of static aeroelastic deformation and flutter stabilities of curved panels in hypersonic flow. In addition, comparisons are made between results obtained by using the present method and curvature modified method. It shows that when the curvature of the curved panel is relatively small, the static aeroelastic deformations and flutter stability boundaries obtained by these two methods have little difference, while for curved panels with larger curvatures, the static aeroelastic deformation obtained by the present method is larger and the flutter stability boundary is smaller compared with those obtained by the curvature modified method, and the discrepancy increases with the increasing of curvature of panels. Therefore, the existing curvature modified method is non-conservative compared to the proposed flow field modified method based on the consideration of hypersonic flight vehicle safety, and the proposed flow field modified local piston theory for curved panels enlarges the application range of piston theory.

  7. Comparison and combination of "direct" and fragment based local correlation methods: Cluster in molecules and domain based local pair natural orbital perturbation and coupled cluster theories

    NASA Astrophysics Data System (ADS)

    Guo, Yang; Becker, Ute; Neese, Frank

    2018-03-01

    Local correlation theories have been developed in two main flavors: (1) "direct" local correlation methods apply local approximation to the canonical equations and (2) fragment based methods reconstruct the correlation energy from a series of smaller calculations on subsystems. The present work serves two purposes. First, we investigate the relative efficiencies of the two approaches using the domain-based local pair natural orbital (DLPNO) approach as the "direct" method and the cluster in molecule (CIM) approach as the fragment based approach. Both approaches are applied in conjunction with second-order many-body perturbation theory (MP2) as well as coupled-cluster theory with single-, double- and perturbative triple excitations [CCSD(T)]. Second, we have investigated the possible merits of combining the two approaches by performing CIM calculations with DLPNO methods serving as the method of choice for performing the subsystem calculations. Our cluster-in-molecule approach is closely related to but slightly deviates from approaches in the literature since we have avoided real space cutoffs. Moreover, the neglected distant pair correlations in the previous CIM approach are considered approximately. Six very large molecules (503-2380 atoms) were studied. At both MP2 and CCSD(T) levels of theory, the CIM and DLPNO methods show similar efficiency. However, DLPNO methods are more accurate for 3-dimensional systems. While we have found only little incentive for the combination of CIM with DLPNO-MP2, the situation is different for CIM-DLPNO-CCSD(T). This combination is attractive because (1) the better parallelization opportunities offered by CIM; (2) the methodology is less memory intensive than the genuine DLPNO-CCSD(T) method and, hence, allows for large calculations on more modest hardware; and (3) the methodology is applicable and efficient in the frequently met cases, where the largest subsystem calculation is too large for the canonical CCSD(T) method.

  8. Feasibility and repeatability of localized (31) P-MRS four-angle saturation transfer (FAST) of the human gastrocnemius muscle using a surface coil at 7 T.

    PubMed

    Tušek Jelenc, Marjeta; Chmelík, Marek; Bogner, Wolfgang; Krššák, Martin; Trattnig, Siegfried; Valkovič, Ladislav

    2016-01-01

    Phosphorus ((31) P) MRS, combined with saturation transfer (ST), provides non-invasive insight into muscle energy metabolism. However, even at 7 T, the standard ST method with T1 (app) measured by inversion recovery takes about 10 min, making it impractical for dynamic examinations. An alternative method, i.e. four-angle saturation transfer (FAST), can shorten the examination time. The aim of this study was to test the feasibility, repeatability, and possible time resolution of the localized FAST technique measurement on an ultra-high-field MR system, to accelerate the measurement of both Pi -to-ATP and PCr-to-ATP reaction rates in the human gastrocnemius muscle and to test the feasibility of using the FAST method for dynamic measurements. We measured the exchange rates and metabolic fluxes in the gastrocnemius muscle of eight healthy subjects at 7 T with the depth-resolved surface coil MRS (DRESS)-localized FAST method. For comparison, a standard ST localized method was also used. The measurement time for the localized FAST experiment was 3.5 min compared with the 10 min for the standard localized ST experiment. In addition, in five healthy volunteers, Pi -to-ATP and PCr-to-ATP metabolic fluxes were measured in the gastrocnemius muscle at rest and during plantar flexion by the DRESS-localized FAST method. The repeatability of PCr-to-ATP and Pi -to-ATP exchange rate constants, determined by the slab-selective localized FAST method at 7 T, is high, as the coefficients of variation remained below 20%, and the results of the exchange rates measured with the FAST method are comparable to those measured with standard ST. During physical activity, the PCr-to-ATP metabolic flux decreased (from FCK  = 8.21 ± 1.15 mM s(-1) to FCK  = 3.86 ± 1.38 mM s(-1) ) and the Pi -to-ATP flux increased (from FATP  = 0.43 ± 0.14 mM s(-1) to FATP  = 0.74 ± 0.13 mM s(-1) ). In conclusion, we could demonstrate that measurements in the gastrocnemius muscle are feasible at rest and are short enough to be used during exercise with the DRESS-localized FAST method at 7 T. Copyright © 2015 John Wiley & Sons, Ltd.

  9. Detecting wood surface defects with fusion algorithm of visual saliency and local threshold segmentation

    NASA Astrophysics Data System (ADS)

    Wang, Xuejuan; Wu, Shuhang; Liu, Yunpeng

    2018-04-01

    This paper presents a new method for wood defect detection. It can solve the over-segmentation problem existing in local threshold segmentation methods. This method effectively takes advantages of visual saliency and local threshold segmentation. Firstly, defect areas are coarsely located by using spectral residual method to calculate global visual saliency of them. Then, the threshold segmentation of maximum inter-class variance method is adopted for positioning and segmenting the wood surface defects precisely around the coarse located areas. Lastly, we use mathematical morphology to process the binary images after segmentation, which reduces the noise and small false objects. Experiments on test images of insect hole, dead knot and sound knot show that the method we proposed obtains ideal segmentation results and is superior to the existing segmentation methods based on edge detection, OSTU and threshold segmentation.

  10. Single Image Super-Resolution Using Global Regression Based on Multiple Local Linear Mappings.

    PubMed

    Choi, Jae-Seok; Kim, Munchurl

    2017-03-01

    Super-resolution (SR) has become more vital, because of its capability to generate high-quality ultra-high definition (UHD) high-resolution (HR) images from low-resolution (LR) input images. Conventional SR methods entail high computational complexity, which makes them difficult to be implemented for up-scaling of full-high-definition input images into UHD-resolution images. Nevertheless, our previous super-interpolation (SI) method showed a good compromise between Peak-Signal-to-Noise Ratio (PSNR) performances and computational complexity. However, since SI only utilizes simple linear mappings, it may fail to precisely reconstruct HR patches with complex texture. In this paper, we present a novel SR method, which inherits the large-to-small patch conversion scheme from SI but uses global regression based on local linear mappings (GLM). Thus, our new SR method is called GLM-SI. In GLM-SI, each LR input patch is divided into 25 overlapped subpatches. Next, based on the local properties of these subpatches, 25 different local linear mappings are applied to the current LR input patch to generate 25 HR patch candidates, which are then regressed into one final HR patch using a global regressor. The local linear mappings are learned cluster-wise in our off-line training phase. The main contribution of this paper is as follows: Previously, linear-mapping-based conventional SR methods, including SI only used one simple yet coarse linear mapping to each patch to reconstruct its HR version. On the contrary, for each LR input patch, our GLM-SI is the first to apply a combination of multiple local linear mappings, where each local linear mapping is found according to local properties of the current LR patch. Therefore, it can better approximate nonlinear LR-to-HR mappings for HR patches with complex texture. Experiment results show that the proposed GLM-SI method outperforms most of the state-of-the-art methods, and shows comparable PSNR performance with much lower computational complexity when compared with a super-resolution method based on convolutional neural nets (SRCNN15). Compared with the previous SI method that is limited with a scale factor of 2, GLM-SI shows superior performance with average 0.79 dB higher in PSNR, and can be used for scale factors of 3 or higher.

  11. Development and application of a local linearization algorithm for the integration of quaternion rate equations in real-time flight simulation problems

    NASA Technical Reports Server (NTRS)

    Barker, L. E., Jr.; Bowles, R. L.; Williams, L. H.

    1973-01-01

    High angular rates encountered in real-time flight simulation problems may require a more stable and accurate integration method than the classical methods normally used. A study was made to develop a general local linearization procedure of integrating dynamic system equations when using a digital computer in real-time. The procedure is specifically applied to the integration of the quaternion rate equations. For this application, results are compared to a classical second-order method. The local linearization approach is shown to have desirable stability characteristics and gives significant improvement in accuracy over the classical second-order integration methods.

  12. Ictal SPECT using an attachable automated injector: clinical usefulness in the prediction of ictal onset zone.

    PubMed

    Lee, Jung-Ju; Lee, Sang Kun; Choi, Jang Wuk; Kim, Dong-Wook; Park, Kyung Il; Kim, Bom Sahn; Kang, Hyejin; Lee, Dong Soo; Lee, Seo-Young; Kim, Sung Hun; Chung, Chun Kee; Nam, Hyeon Woo; Kim, Kwang Ki

    2009-12-01

    Ictal single-photon emission computed tomography (SPECT) is a valuable method for localizing the ictal onset zone in the presurgical evaluation of patients with intractable epilepsy. Conventional methods used to localize the ictal onset zone have problems with time lag from seizure onset to injection. To evaluate the clinical usefulness of a method that we developed, which involves an attachable automated injector (AAI), in reducing time lag and improving the ability to localize the zone of seizure onset. Patients admitted to the epilepsy monitoring unit (EMU) between January 1, 2003, and June 30, 2008, were included. The definition of ictal onset zone was made by comprehensive review of medical records, magnetic resonance imaging (MRI), data from video electroencephalography (EEG) monitoring, and invasive EEG monitoring if available. We comprehensively evaluated the time lag to injection and the image patterns of ictal SPECT using traditional visual analysis, statistical parametric mapping-assisted, and subtraction ictal SPECT coregistered to an MRI-assisted means of analysis. Image patterns were classified as localizing, lateralizing, and nonlateralizing. The whole number of patients was 99: 48 in the conventional group and 51 in the AAI group. The mean (SD) delay time to injection from seizure onset was 12.4+/-12.0 s in the group injected by our AAI method and 40.4+/-26.3 s in the group injected by the conventional method (P=0.000). The mean delay time to injection from seizure detection was 3.2+/-2.5 s in the group injected by the AAI method and 21.4+/-9.7 s in the group injected by the conventional method (P=0.000). The AAI method was superior to the conventional method in localizing the area of seizure onset (36 out of 51 with AAI method vs. 21 out of 48 with conventional method, P=0.009), especially in non-temporal lobe epilepsy (non-TLE) patients (17 out of 27 with AAI method vs. 3 out of 13 with conventional method, P=0.041), and in lateralizing the seizure onset hemisphere (47 out of 51 with AAI method vs. 33 out of 48 with conventional method, P=0.004). The AAI method was superior to the conventional method in reducing the time lag of tracer injection and in localizing and lateralizing the ictal onset zone, especially in patients with non-TLE.

  13. Iterative raw measurements restoration method with penalized weighted least squares approach for low-dose CT

    NASA Astrophysics Data System (ADS)

    Takahashi, Hisashi; Goto, Taiga; Hirokawa, Koichi; Miyazaki, Osamu

    2014-03-01

    Statistical iterative reconstruction and post-log data restoration algorithms for CT noise reduction have been widely studied and these techniques have enabled us to reduce irradiation doses while maintaining image qualities. In low dose scanning, electronic noise becomes obvious and it results in some non-positive signals in raw measurements. The nonpositive signal should be converted to positive signal so that it can be log-transformed. Since conventional conversion methods do not consider local variance on the sinogram, they have difficulty of controlling the strength of the filtering. Thus, in this work, we propose a method to convert the non-positive signal to the positive signal by mainly controlling the local variance. The method is implemented in two separate steps. First, an iterative restoration algorithm based on penalized weighted least squares is used to mitigate the effect of electronic noise. The algorithm preserves the local mean and reduces the local variance induced by the electronic noise. Second, smoothed raw measurements by the iterative algorithm are converted to the positive signal according to a function which replaces the non-positive signal with its local mean. In phantom studies, we confirm that the proposed method properly preserves the local mean and reduce the variance induced by the electronic noise. Our technique results in dramatically reduced shading artifacts and can also successfully cooperate with the post-log data filter to reduce streak artifacts.

  14. A simple, rapid and inexpensive method for localization of Tomato yellow leaf curl virus and Potato leafroll virus in plant and insect vectors.

    PubMed

    Ghanim, Murad; Brumin, Marina; Popovski, Smadar

    2009-08-01

    A simple, rapid, inexpensive method for the localization of virus transcripts in plant and insect vector tissues is reported here. The method based on fluorescent in situ hybridization using short DNA oligonucleotides complementary to an RNA segment representing a virus transcript in the infected plant or insect vector. The DNA probe harbors a fluorescent molecule at its 5' or 3' ends. The protocol: simple fixation, hybridization, minimal washing and confocal microscopy, provides a highly specific signal. The reliability of the protocol was tested by localizing two phloem-limited plant virus transcripts in infected plants and insect tissues: Tomato yellow leaf curl virus (TYLCV) (Begomovirus: Geminiviridae), exclusively transmitted by the whitefly Bemisia tabaci (Gennadius) in a circulative non-propagative manner, and Potato leafroll virus (Polerovirus: Luteoviridae), similarly transmitted by the aphid Myzus persicae (Sulzer). Transcripts for both viruses were localized specifically to the phloem sieve elements of infected plants, while negative controls showed no signal. TYLCV transcripts were also localized to the digestive tract of B. tabaci, confirming TYLCV route of transmission. Compared to previous methods for localizing virus transcripts in plant and insect tissues that include complex steps for in-vitro probe preparation or antibody raising, tissue fixation, block preparation, sectioning and hybridization, the method described below provides very reliable, convincing, background-free results with much less time, effort and cost.

  15. Turbine heat transfer

    NASA Technical Reports Server (NTRS)

    Rohde, J. E.

    1982-01-01

    Objectives and approaches to research in turbine heat transfer are discussed. Generally, improvements in the method of determining the hot gas flow through the turbine passage is one area of concern, as is the cooling air flow inside the airfoil, and the methods of predicting the heat transfer rates on the hot gas side and on the coolant side of the airfoil. More specific areas of research are: (1) local hot gas recovery temperatures along the airfoil surfaces; (2) local airfoil wall temperature; (3) local hot gas side heat transfer coefficients on the airfoil surfaces; (4) local coolant side heat transfer coefficients inside the airfoils; (5) local hot gas flow velocities and secondary flows at real engine conditions; and (6) local delta strain range of the airfoil walls.

  16. Computing wave functions in multichannel collisions with non-local potentials using the R-matrix method

    NASA Astrophysics Data System (ADS)

    Bonitati, Joey; Slimmer, Ben; Li, Weichuan; Potel, Gregory; Nunes, Filomena

    2017-09-01

    The calculable form of the R-matrix method has been previously shown to be a useful tool in approximately solving the Schrodinger equation in nuclear scattering problems. We use this technique combined with the Gauss quadrature for the Lagrange-mesh method to efficiently solve for the wave functions of projectile nuclei in low energy collisions (1-100 MeV) involving an arbitrary number of channels. We include the local Woods-Saxon potential, the non-local potential of Perey and Buck, a Coulomb potential, and a coupling potential to computationally solve for the wave function of two nuclei at short distances. Object oriented programming is used to increase modularity, and parallel programming techniques are introduced to reduce computation time. We conclude that the R-matrix method is an effective method to predict the wave functions of nuclei in scattering problems involving both multiple channels and non-local potentials. Michigan State University iCER ACRES REU.

  17. A locally conservative stabilized continuous Galerkin finite element method for two-phase flow in poroelastic subsurfaces

    NASA Astrophysics Data System (ADS)

    Deng, Q.; Ginting, V.; McCaskill, B.; Torsu, P.

    2017-10-01

    We study the application of a stabilized continuous Galerkin finite element method (CGFEM) in the simulation of multiphase flow in poroelastic subsurfaces. The system involves a nonlinear coupling between the fluid pressure, subsurface's deformation, and the fluid phase saturation, and as such, we represent this coupling through an iterative procedure. Spatial discretization of the poroelastic system employs the standard linear finite element in combination with a numerical diffusion term to maintain stability of the algebraic system. Furthermore, direct calculation of the normal velocities from pressure and deformation does not entail a locally conservative field. To alleviate this drawback, we propose an element based post-processing technique through which local conservation can be established. The performance of the method is validated through several examples illustrating the convergence of the method, the effectivity of the stabilization term, and the ability to achieve locally conservative normal velocities. Finally, the efficacy of the method is demonstrated through simulations of realistic multiphase flow in poroelastic subsurfaces.

  18. Customization of UWB 3D-RTLS Based on the New Uncertainty Model of the AoA Ranging Technique

    PubMed Central

    Jachimczyk, Bartosz; Dziak, Damian; Kulesza, Wlodek J.

    2017-01-01

    The increased potential and effectiveness of Real-time Locating Systems (RTLSs) substantially influence their application spectrum. They are widely used, inter alia, in the industrial sector, healthcare, home care, and in logistic and security applications. The research aims to develop an analytical method to customize UWB-based RTLS, in order to improve their localization performance in terms of accuracy and precision. The analytical uncertainty model of Angle of Arrival (AoA) localization in a 3D indoor space, which is the foundation of the customization concept, is established in a working environment. Additionally, a suitable angular-based 3D localization algorithm is introduced. The paper investigates the following issues: the influence of the proposed correction vector on the localization accuracy; the impact of the system’s configuration and LS’s relative deployment on the localization precision distribution map. The advantages of the method are verified by comparing them with a reference commercial RTLS localization engine. The results of simulations and physical experiments prove the value of the proposed customization method. The research confirms that the analytical uncertainty model is the valid representation of RTLS’ localization uncertainty in terms of accuracy and precision and can be useful for its performance improvement. The research shows, that the Angle of Arrival localization in a 3D indoor space applying the simple angular-based localization algorithm and correction vector improves of localization accuracy and precision in a way that the system challenges the reference hardware advanced localization engine. Moreover, the research guides the deployment of location sensors to enhance the localization precision. PMID:28125056

  19. Customization of UWB 3D-RTLS Based on the New Uncertainty Model of the AoA Ranging Technique.

    PubMed

    Jachimczyk, Bartosz; Dziak, Damian; Kulesza, Wlodek J

    2017-01-25

    The increased potential and effectiveness of Real-time Locating Systems (RTLSs) substantially influence their application spectrum. They are widely used, inter alia, in the industrial sector, healthcare, home care, and in logistic and security applications. The research aims to develop an analytical method to customize UWB-based RTLS, in order to improve their localization performance in terms of accuracy and precision. The analytical uncertainty model of Angle of Arrival (AoA) localization in a 3D indoor space, which is the foundation of the customization concept, is established in a working environment. Additionally, a suitable angular-based 3D localization algorithm is introduced. The paper investigates the following issues: the influence of the proposed correction vector on the localization accuracy; the impact of the system's configuration and LS's relative deployment on the localization precision distribution map. The advantages of the method are verified by comparing them with a reference commercial RTLS localization engine. The results of simulations and physical experiments prove the value of the proposed customization method. The research confirms that the analytical uncertainty model is the valid representation of RTLS' localization uncertainty in terms of accuracy and precision and can be useful for its performance improvement. The research shows, that the Angle of Arrival localization in a 3D indoor space applying the simple angular-based localization algorithm and correction vector improves of localization accuracy and precision in a way that the system challenges the reference hardware advanced localization engine. Moreover, the research guides the deployment of location sensors to enhance the localization precision.

  20. Mobile robot self-localization system using single webcam distance measurement technology in indoor environments.

    PubMed

    Li, I-Hsum; Chen, Ming-Chang; Wang, Wei-Yen; Su, Shun-Feng; Lai, To-Wen

    2014-01-27

    A single-webcam distance measurement technique for indoor robot localization is proposed in this paper. The proposed localization technique uses webcams that are available in an existing surveillance environment. The developed image-based distance measurement system (IBDMS) and parallel lines distance measurement system (PLDMS) have two merits. Firstly, only one webcam is required for estimating the distance. Secondly, the set-up of IBDMS and PLDMS is easy, which only one known-dimension rectangle pattern is needed, i.e., a ground tile. Some common and simple image processing techniques, i.e., background subtraction are used to capture the robot in real time. Thus, for the purposes of indoor robot localization, the proposed method does not need to use expensive high-resolution webcams and complicated pattern recognition methods but just few simple estimating formulas. From the experimental results, the proposed robot localization method is reliable and effective in an indoor environment.

  1. Evaluation Methodology between Globalization and Localization Features Approaches for Skin Cancer Lesions Classification

    NASA Astrophysics Data System (ADS)

    Ahmed, H. M.; Al-azawi, R. J.; Abdulhameed, A. A.

    2018-05-01

    Huge efforts have been put in the developing of diagnostic methods to skin cancer disease. In this paper, two different approaches have been addressed for detection the skin cancer in dermoscopy images. The first approach uses a global method that uses global features for classifying skin lesions, whereas the second approach uses a local method that uses local features for classifying skin lesions. The aim of this paper is selecting the best approach for skin lesion classification. The dataset has been used in this paper consist of 200 dermoscopy images from Pedro Hispano Hospital (PH2). The achieved results are; sensitivity about 96%, specificity about 100%, precision about 100%, and accuracy about 97% for globalization approach while, sensitivity about 100%, specificity about 100%, precision about 100%, and accuracy about 100% for Localization Approach, these results showed that the localization approach achieved acceptable accuracy and better than globalization approach for skin cancer lesions classification.

  2. Mobile Robot Self-Localization System Using Single Webcam Distance Measurement Technology in Indoor Environments

    PubMed Central

    Li, I-Hsum; Chen, Ming-Chang; Wang, Wei-Yen; Su, Shun-Feng; Lai, To-Wen

    2014-01-01

    A single-webcam distance measurement technique for indoor robot localization is proposed in this paper. The proposed localization technique uses webcams that are available in an existing surveillance environment. The developed image-based distance measurement system (IBDMS) and parallel lines distance measurement system (PLDMS) have two merits. Firstly, only one webcam is required for estimating the distance. Secondly, the set-up of IBDMS and PLDMS is easy, which only one known-dimension rectangle pattern is needed, i.e., a ground tile. Some common and simple image processing techniques, i.e., background subtraction are used to capture the robot in real time. Thus, for the purposes of indoor robot localization, the proposed method does not need to use expensive high-resolution webcams and complicated pattern recognition methods but just few simple estimating formulas. From the experimental results, the proposed robot localization method is reliable and effective in an indoor environment. PMID:24473282

  3. A Synthetic Comparator Approach to Local Evaluation of School-Based Substance Use Prevention Programming.

    PubMed

    Hansen, William B; Derzon, James H; Reese, Eric L

    2014-06-01

    We propose a method for creating groups against which outcomes of local pretest-posttest evaluations of evidence-based programs can be judged. This involves assessing pretest markers for new and previously conducted evaluations to identify groups that have high pretest similarity. A database of 802 prior local evaluations provided six summary measures for analysis. The proximity of all groups using these variables is calculated as standardized proximities having values between 0 and 1. Five methods for creating standardized proximities are demonstrated. The approach allows proximity limits to be adjusted to find sufficient numbers of synthetic comparators. Several index cases are examined to assess the numbers of groups available to serve as comparators. Results show that most local evaluations would have sufficient numbers of comparators available for estimating program effects. This method holds promise as a tool for local evaluations to estimate relative effectiveness. © The Author(s) 2012.

  4. Simulations of Fractal Star Cluster Formation. I. New Insights for Measuring Mass Segregation of Star Clusters with Substructure

    NASA Astrophysics Data System (ADS)

    Yu, Jincheng; Puzia, Thomas H.; Lin, Congping; Zhang, Yiwei

    2017-05-01

    We compare the existent methods, including the minimum spanning tree based method and the local stellar density based method, in measuring mass segregation of star clusters. We find that the minimum spanning tree method reflects more the compactness, which represents the global spatial distribution of massive stars, while the local stellar density method reflects more the crowdedness, which provides the local gravitational potential information. It is suggested to measure the local and the global mass segregation simultaneously. We also develop a hybrid method that takes both aspects into account. This hybrid method balances the local and the global mass segregation in the sense that the predominant one is either caused by dynamical evolution or purely accidental, especially when such information is unknown a priori. In addition, we test our prescriptions with numerical models and show the impact of binaries in estimating the mass segregation value. As an application, we use these methods on the Orion Nebula Cluster (ONC) observations and the Taurus cluster. We find that the ONC is significantly mass segregated down to the 20th most massive stars. In contrast, the massive stars of the Taurus cluster are sparsely distributed in many different subclusters, showing a low degree of compactness. The massive stars of Taurus are also found to be distributed in the high-density region of the subclusters, showing significant mass segregation at subcluster scales. Meanwhile, we also apply these methods to discuss the possible mechanisms of the dynamical evolution of the simulated substructured star clusters.

  5. Simulations of Fractal Star Cluster Formation. I. New Insights for Measuring Mass Segregation of Star Clusters with Substructure

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yu, Jincheng; Puzia, Thomas H.; Lin, Congping

    2017-05-10

    We compare the existent methods, including the minimum spanning tree based method and the local stellar density based method, in measuring mass segregation of star clusters. We find that the minimum spanning tree method reflects more the compactness, which represents the global spatial distribution of massive stars, while the local stellar density method reflects more the crowdedness, which provides the local gravitational potential information. It is suggested to measure the local and the global mass segregation simultaneously. We also develop a hybrid method that takes both aspects into account. This hybrid method balances the local and the global mass segregationmore » in the sense that the predominant one is either caused by dynamical evolution or purely accidental, especially when such information is unknown a priori. In addition, we test our prescriptions with numerical models and show the impact of binaries in estimating the mass segregation value. As an application, we use these methods on the Orion Nebula Cluster (ONC) observations and the Taurus cluster. We find that the ONC is significantly mass segregated down to the 20th most massive stars. In contrast, the massive stars of the Taurus cluster are sparsely distributed in many different subclusters, showing a low degree of compactness. The massive stars of Taurus are also found to be distributed in the high-density region of the subclusters, showing significant mass segregation at subcluster scales. Meanwhile, we also apply these methods to discuss the possible mechanisms of the dynamical evolution of the simulated substructured star clusters.« less

  6. Homogenization of periodic bi-isotropic composite materials

    NASA Astrophysics Data System (ADS)

    Ouchetto, Ouail; Essakhi, Brahim

    2018-07-01

    In this paper, we present a new method for homogenizing the bi-periodic materials with bi-isotropic components phases. The presented method is a numerical method based on the finite element method to compute the local electromagnetic properties. The homogenized constitutive parameters are expressed as a function of the macroscopic electromagnetic properties which are obtained from the local properties. The obtained results are compared to Unfolding Finite Element Method and Maxwell-Garnett formulas.

  7. Local Linear Observed-Score Equating

    ERIC Educational Resources Information Center

    Wiberg, Marie; van der Linden, Wim J.

    2011-01-01

    Two methods of local linear observed-score equating for use with anchor-test and single-group designs are introduced. In an empirical study, the two methods were compared with the current traditional linear methods for observed-score equating. As a criterion, the bias in the equated scores relative to true equating based on Lord's (1980)…

  8. Local constitutive behavior of paper determined by an inverse method

    Treesearch

    John M. Considine; C. Tim Scott; Roland Gleisner; Junyong Zhu

    2006-01-01

    The macroscopic behavior of paper is governed by small-scale behavior. Intuitively, we know that a small-scale defect with a paper sheet effectively determines the global behavior of the sheet. In this work, we describe a method to evaluate the local constitutive behavior of paper by using an inverse method.

  9. Distributed least-squares estimation of a remote chemical source via convex combination in wireless sensor networks.

    PubMed

    Cao, Meng-Li; Meng, Qing-Hao; Zeng, Ming; Sun, Biao; Li, Wei; Ding, Cheng-Jun

    2014-06-27

    This paper investigates the problem of locating a continuous chemical source using the concentration measurements provided by a wireless sensor network (WSN). Such a problem exists in various applications: eliminating explosives or drugs, detecting the leakage of noxious chemicals, etc. The limited power and bandwidth of WSNs have motivated collaborative in-network processing which is the focus of this paper. We propose a novel distributed least-squares estimation (DLSE) method to solve the chemical source localization (CSL) problem using a WSN. The DLSE method is realized by iteratively conducting convex combination of the locally estimated chemical source locations in a distributed manner. Performance assessments of our method are conducted using both simulations and real experiments. In the experiments, we propose a fitting method to identify both the release rate and the eddy diffusivity. The results show that the proposed DLSE method can overcome the negative interference of local minima and saddle points of the objective function, which would hinder the convergence of local search methods, especially in the case of locating a remote chemical source.

  10. Estimation of the reproduction number of dengue fever from spatial epidemic data.

    PubMed

    Chowell, G; Diaz-Dueñas, P; Miller, J C; Alcazar-Velazco, A; Hyman, J M; Fenimore, P W; Castillo-Chavez, C

    2007-08-01

    Dengue, a vector-borne disease, thrives in tropical and subtropical regions worldwide. A retrospective analysis of the 2002 dengue epidemic in Colima located on the Mexican central Pacific coast is carried out. We estimate the reproduction number from spatial epidemic data at the level of municipalities using two different methods: (1) Using a standard dengue epidemic model and assuming pure exponential initial epidemic growth and (2) Fitting a more realistic epidemic model to the initial phase of the dengue epidemic curve. Using Method I, we estimate an overall mean reproduction number of 3.09 (95% CI: 2.34,3.84) as well as local reproduction numbers whose values range from 1.24 (1.15,1.33) to 4.22 (2.90,5.54). Using Method II, the overall mean reproduction number is estimated to be 2.0 (1.75,2.23) and local reproduction numbers ranging from 0.49 (0.0,1.0) to 3.30 (1.63,4.97). Method I systematically overestimates the reproduction number relative to the refined Method II, and hence it would overestimate the intensity of interventions required for containment. Moreover, optimal intervention with defined resources demands different levels of locally tailored mitigation. Local epidemic peaks occur between the 24th and 35th week of the year, and correlate positively with the final local epidemic sizes (rho=0.92, P-value<0.001). Moreover, final local epidemic sizes are found to be linearly related to the local population size (P-value<0.001). This observation supports a roughly constant number of female mosquitoes per person across urban and rural regions.

  11. Collective network routing

    DOEpatents

    Hoenicke, Dirk

    2014-12-02

    Disclosed are a unified method and apparatus to classify, route, and process injected data packets into a network so as to belong to a plurality of logical networks, each implementing a specific flow of data on top of a common physical network. The method allows to locally identify collectives of packets for local processing, such as the computation of the sum, difference, maximum, minimum, or other logical operations among the identified packet collective. Packets are injected together with a class-attribute and an opcode attribute. Network routers, employing the described method, use the packet attributes to look-up the class-specific route information from a local route table, which contains the local incoming and outgoing directions as part of the specifically implemented global data flow of the particular virtual network.

  12. Feature Genes Selection Using Supervised Locally Linear Embedding and Correlation Coefficient for Microarray Classification

    PubMed Central

    Wang, Yun; Huang, Fangzhou

    2018-01-01

    The selection of feature genes with high recognition ability from the gene expression profiles has gained great significance in biology. However, most of the existing methods have a high time complexity and poor classification performance. Motivated by this, an effective feature selection method, called supervised locally linear embedding and Spearman's rank correlation coefficient (SLLE-SC2), is proposed which is based on the concept of locally linear embedding and correlation coefficient algorithms. Supervised locally linear embedding takes into account class label information and improves the classification performance. Furthermore, Spearman's rank correlation coefficient is used to remove the coexpression genes. The experiment results obtained on four public tumor microarray datasets illustrate that our method is valid and feasible. PMID:29666661

  13. Feature Genes Selection Using Supervised Locally Linear Embedding and Correlation Coefficient for Microarray Classification.

    PubMed

    Xu, Jiucheng; Mu, Huiyu; Wang, Yun; Huang, Fangzhou

    2018-01-01

    The selection of feature genes with high recognition ability from the gene expression profiles has gained great significance in biology. However, most of the existing methods have a high time complexity and poor classification performance. Motivated by this, an effective feature selection method, called supervised locally linear embedding and Spearman's rank correlation coefficient (SLLE-SC 2 ), is proposed which is based on the concept of locally linear embedding and correlation coefficient algorithms. Supervised locally linear embedding takes into account class label information and improves the classification performance. Furthermore, Spearman's rank correlation coefficient is used to remove the coexpression genes. The experiment results obtained on four public tumor microarray datasets illustrate that our method is valid and feasible.

  14. The P1-RKDG method for two-dimensional Euler equations of gas dynamics

    NASA Technical Reports Server (NTRS)

    Cockburn, Bernardo; Shu, Chi-Wang

    1991-01-01

    A class of nonlinearly stable Runge-Kutta local projection discontinuous Galerkin (RKDG) finite element methods for conservation laws is investigated. Two dimensional Euler equations for gas dynamics are solved using P1 elements. The generalization of the local projections, which for scalar nonlinear conservation laws was designed to satisfy a local maximum principle, to systems of conservation laws such as the Euler equations of gas dynamics using local characteristic decompositions is discussed. Numerical examples include the standard regular shock reflection problem, the forward facing step problem, and the double Mach reflection problem. These preliminary numerical examples are chosen to show the capacity of the approach to obtain nonlinearly stable results comparable with the modern nonoscillatory finite difference methods.

  15. Aluminum alloy material structure impact localization by using FBG sensors

    NASA Astrophysics Data System (ADS)

    Zhu, Xiubin

    2014-12-01

    The aluminum alloy structure impact localization system by using fiber Bragg grating (FBG) sensors and impact localization algorithm was investigated. A four-FBG sensing network was established. And the power intensity demodulation method was initialized employing the narrow-band tunable laser. The wavelet transform was used to weaken the impact signal noise. And the impact signal time difference was extracted to build the time difference localization algorithm. At last, a fiber Bragg grating impact localization system was established and experimentally verified. The experimental results showed that in the aluminum alloy plate with the 500 mm*500 mm*2 mm test area, the maximum and average impact abscissa localization errors were 11 mm and 6.25 mm, and the maximum and average impact ordinate localization errors were 9 mm and 4.25 mm, respectively. The fiber Bragg grating sensors and demodulation system are feasible to realize the aviation aluminum alloy material structure impact localization. The research results provide a reliable method for the aluminum alloy material structure impact localization.

  16. Localized saddle-point search and application to temperature-accelerated dynamics

    NASA Astrophysics Data System (ADS)

    Shim, Yunsic; Callahan, Nathan B.; Amar, Jacques G.

    2013-03-01

    We present a method for speeding up temperature-accelerated dynamics (TAD) simulations by carrying out a localized saddle-point (LSAD) search. In this method, instead of using the entire system to determine the energy barriers of activated processes, the calculation is localized by only including a small chunk of atoms around the atoms directly involved in the transition. Using this method, we have obtained N-independent scaling for the computational cost of the saddle-point search as a function of system size N. The error arising from localization is analyzed using a variety of model systems, including a variety of activated processes on Ag(100) and Cu(100) surfaces, as well as multiatom moves in Cu radiation damage and metal heteroepitaxial growth. Our results show significantly improved performance of TAD with the LSAD method, for the case of Ag/Ag(100) annealing and Cu/Cu(100) growth, while maintaining a negligibly small error in energy barriers.

  17. Binding ligand prediction for proteins using partial matching of local surface patches.

    PubMed

    Sael, Lee; Kihara, Daisuke

    2010-01-01

    Functional elucidation of uncharacterized protein structures is an important task in bioinformatics. We report our new approach for structure-based function prediction which captures local surface features of ligand binding pockets. Function of proteins, specifically, binding ligands of proteins, can be predicted by finding similar local surface regions of known proteins. To enable partial comparison of binding sites in proteins, a weighted bipartite matching algorithm is used to match pairs of surface patches. The surface patches are encoded with the 3D Zernike descriptors. Unlike the existing methods which compare global characteristics of the protein fold or the global pocket shape, the local surface patch method can find functional similarity between non-homologous proteins and binding pockets for flexible ligand molecules. The proposed method improves prediction results over global pocket shape-based method which was previously developed by our group.

  18. Binding Ligand Prediction for Proteins Using Partial Matching of Local Surface Patches

    PubMed Central

    Sael, Lee; Kihara, Daisuke

    2010-01-01

    Functional elucidation of uncharacterized protein structures is an important task in bioinformatics. We report our new approach for structure-based function prediction which captures local surface features of ligand binding pockets. Function of proteins, specifically, binding ligands of proteins, can be predicted by finding similar local surface regions of known proteins. To enable partial comparison of binding sites in proteins, a weighted bipartite matching algorithm is used to match pairs of surface patches. The surface patches are encoded with the 3D Zernike descriptors. Unlike the existing methods which compare global characteristics of the protein fold or the global pocket shape, the local surface patch method can find functional similarity between non-homologous proteins and binding pockets for flexible ligand molecules. The proposed method improves prediction results over global pocket shape-based method which was previously developed by our group. PMID:21614188

  19. Scanning tunneling spectroscopy under large current flow through the sample.

    PubMed

    Maldonado, A; Guillamón, I; Suderow, H; Vieira, S

    2011-07-01

    We describe a method to make scanning tunneling microscopy/spectroscopy imaging at very low temperatures while driving a constant electric current up to some tens of mA through the sample. It gives a new local probe, which we term current driven scanning tunneling microscopy/spectroscopy. We show spectroscopic and topographic measurements under the application of a current in superconducting Al and NbSe(2) at 100 mK. Perspective of applications of this local imaging method includes local vortex motion experiments, and Doppler shift local density of states studies.

  20. Local-Level Prognostics Health Management Systems Framework for Passive AdvSMR Components. Interim Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ramuhalli, Pradeep; Roy, Surajit; Hirt, Evelyn H.

    2014-09-12

    This report describes research results to date in support of the integration and demonstration of diagnostics technologies for prototypical AdvSMR passive components (to establish condition indices for monitoring) with model-based prognostics methods. The focus of the PHM methodology and algorithm development in this study is at the localized scale. Multiple localized measurements of material condition (using advanced nondestructive measurement methods), along with available measurements of the stressor environment, enhance the performance of localized diagnostics and prognostics of passive AdvSMR components and systems.

  1. The effective local potential method: Implementation for molecules and relation to approximate optimized effective potential techniques

    NASA Astrophysics Data System (ADS)

    Izmaylov, Artur F.; Staroverov, Viktor N.; Scuseria, Gustavo E.; Davidson, Ernest R.; Stoltz, Gabriel; Cancès, Eric

    2007-02-01

    We have recently formulated a new approach, named the effective local potential (ELP) method, for calculating local exchange-correlation potentials for orbital-dependent functionals based on minimizing the variance of the difference between a given nonlocal potential and its desired local counterpart [V. N. Staroverov et al., J. Chem. Phys. 125, 081104 (2006)]. Here we show that under a mildly simplifying assumption of frozen molecular orbitals, the equation defining the ELP has a unique analytic solution which is identical with the expression arising in the localized Hartree-Fock (LHF) and common energy denominator approximations (CEDA) to the optimized effective potential. The ELP procedure differs from the CEDA and LHF in that it yields the target potential as an expansion in auxiliary basis functions. We report extensive calculations of atomic and molecular properties using the frozen-orbital ELP method and its iterative generalization to prove that ELP results agree with the corresponding LHF and CEDA values, as they should. Finally, we make the case for extending the iterative frozen-orbital ELP method to full orbital relaxation.

  2. Confocal laser induced fluorescence with comparable spatial localization to the conventional method

    NASA Astrophysics Data System (ADS)

    Thompson, Derek S.; Henriquez, Miguel F.; Scime, Earl E.; Good, Timothy N.

    2017-10-01

    We present measurements of ion velocity distributions obtained by laser induced fluorescence (LIF) using a single viewport in an argon plasma. A patent pending design, which we refer to as the confocal fluorescence telescope, combines large objective lenses with a large central obscuration and a spatial filter to achieve high spatial localization along the laser injection direction. Models of the injection and collection optics of the two assemblies are used to provide a theoretical estimate of the spatial localization of the confocal arrangement, which is taken to be the full width at half maximum of the spatial optical response. The new design achieves approximately 1.4 mm localization at a focal length of 148.7 mm, improving on previously published designs by an order of magnitude and approaching the localization achieved by the conventional method. The confocal method, however, does so without requiring a pair of separated, perpendicular optical paths. The confocal technique therefore eases the two window access requirement of the conventional method, extending the application of LIF to experiments where conventional LIF measurements have been impossible or difficult, or where multiple viewports are scarce.

  3. Semi-rigid single hook localization the best method for localizing ground glass opacities during video-assisted thoracoscopic surgery: re-aerated swine lung experimental and primary clinical results

    PubMed Central

    Zhao, Guang; Sun, Long; Geng, Guojun; Liu, Hongming; Li, Ning; Liu, Suhuan; Hao, Bing

    2017-01-01

    Background The aim of this study was to compare the effects of currently available preoperative localization methods, including semi-rigid single hook-wire, double-thorn hook-wire, and microcoil, in localizing the pulmonary nodules, thus to select the best technology to assist video-assisted thoracoscopic surgery (VATS) for small ground glass opacities (GGO). Methods Preoperative CT-guided localizing techniques including semi-rigid single hook-wire, double-thorn hook-wire and microcoil were used in re-aerated fresh swine lung for location experiments. The advantages and drawbacks of the three positioning technologies were compared, and then the most optimal technique was used in patients with GGO. Technical success and post-operative complications were used as primary endpoints. Results All three localizing techniques were successfully performed in the re-aerated fresh swine lung. The median tractive force of semi-rigid single hook wire, double-thorn hook wire and microcoil were 6.5, 4.85 and 0.2 N, which measured by a spring dynamometer. The wound sizes in the superficial pleura, caused by unplugging the needles, were 2 mm in double-thorn hook wire, 1 mm in semi-rigid single hook and 1 mm in microcoil, respectively. In patients with GGOs, the semi-rigid hook wires localizations were successfully performed, without any complication that need to be intervened. Dislodgement was reported in one patient before VATS. No major complications related to the preoperative hook wire localization and VATS were observed. Conclusions We found from our localization experiments in the swine lung that, among the commonly used three localization methods, semi-rigid hook wire showed the best operability and practicability than double-thorn hook wire and microcoil. Preoperative localization of small pulmonary nodules with single semi-rigid hook wire system shows a high success rate, acceptable utility and especially low dislodgement in VATS. PMID:29312722

  4. A strategy to find minimal energy nanocluster structures.

    PubMed

    Rogan, José; Varas, Alejandro; Valdivia, Juan Alejandro; Kiwi, Miguel

    2013-11-05

    An unbiased strategy to search for the global and local minimal energy structures of free standing nanoclusters is presented. Our objectives are twofold: to find a diverse set of low lying local minima, as well as the global minimum. To do so, we use massively the fast inertial relaxation engine algorithm as an efficient local minimizer. This procedure turns out to be quite efficient to reach the global minimum, and also most of the local minima. We test the method with the Lennard-Jones (LJ) potential, for which an abundant literature does exist, and obtain novel results, which include a new local minimum for LJ13 , 10 new local minima for LJ14 , and thousands of new local minima for 15≤N≤65. Insights on how to choose the initial configurations, analyzing the effectiveness of the method in reaching low-energy structures, including the global minimum, are developed as a function of the number of atoms of the cluster. Also, a novel characterization of the potential energy surface, analyzing properties of the local minima basins, is provided. The procedure constitutes a promising tool to generate a diverse set of cluster conformations, both two- and three-dimensional, that can be used as an input for refinement by means of ab initio methods. Copyright © 2013 Wiley Periodicals, Inc.

  5. Local resection of the stomach for gastric cancer.

    PubMed

    Kinami, Shinichi; Funaki, Hiroshi; Fujita, Hideto; Nakano, Yasuharu; Ueda, Nobuhiko; Kosaka, Takeo

    2017-06-01

    The local resection of the stomach is an ideal method for preventing postoperative symptoms. There are various procedures for performing local resection, such as the laparoscopic lesion lifting method, non-touch lesion lifting method, endoscopic full-thickness resection, and laparoscopic endoscopic cooperative surgery. After the invention and widespread use of endoscopic submucosal dissection, local resection has become outdated as a curative surgical technique for gastric cancer. Nevertheless, local resection of the stomach in the treatment of gastric cancer in now expected to make a comeback with the clinical use of sentinel node navigation surgery. However, there are many issues associated with local resection for gastric cancer, other than the normal indications. These include gastric deformation, functional impairment, ensuring a safe surgical margin, the possibility of inducing peritoneal dissemination, and the associated increase in the risk of metachronous gastric cancer. In view of these issues, there is a tendency to regard local resection as an investigative treatment, to be applied only in carefully selected cases. The ideal model for local resection of the stomach for gastric cancer would be a combination of endoscopic full-thickness resection of the stomach using an ESD device and hand sutured closure using a laparoscope or a surgical robot, for achieving both oncological safety and preserved functions.

  6. Adjoint-tomography for a Local Surface Structure: Methodology and a Blind Test

    NASA Astrophysics Data System (ADS)

    Kubina, Filip; Michlik, Filip; Moczo, Peter; Kristek, Jozef; Stripajova, Svetlana

    2017-04-01

    We have developed a multiscale full-waveform adjoint-tomography method for local surface sedimentary structures with complicated interference wavefields. The local surface sedimentary basins and valleys are often responsible for anomalous earthquake ground motions and corresponding damage in earthquakes. In many cases only relatively small number of records of a few local earthquakes is available for a site of interest. Consequently, prediction of earthquake ground motion at the site has to include numerical modeling for a realistic model of the local structure. Though limited, the information about the local structure encoded in the records is important and irreplaceable. It is therefore reasonable to have a method capable of using the limited information in records for improving a model of the local structure. A local surface structure and its interference wavefield require a specific multiscale approach. In order to verify our inversion method, we performed a blind test. We obtained synthetic seismograms at 8 receivers for 2 local sources, complete description of the sources, positions of the receivers and material parameters of the bedrock. We considered the simplest possible starting model - a homogeneous halfspace made of the bedrock. Using our inversion method we obtained an inverted model. Given the starting model, synthetic seismograms simulated for the inverted model are surprisingly close to the synthetic seismograms simulated for the true structure in the target frequency range up to 4.5 Hz. We quantify the level of agreement between the true and inverted seismograms using the L2 and time-frequency misfits, and, more importantly for earthquake-engineering applications, also using the goodness-of-fit criteria based on the earthquake-engineering characteristics of earthquake ground motion. We also verified the inverted model for other source-receiver configurations not used in the inversion.

  7. An Efficient Local Correlation Matrix Decomposition Approach for the Localization Implementation of Ensemble-Based Assimilation Methods

    NASA Astrophysics Data System (ADS)

    Zhang, Hongqin; Tian, Xiangjun

    2018-04-01

    Ensemble-based data assimilation methods often use the so-called localization scheme to improve the representation of the ensemble background error covariance (Be). Extensive research has been undertaken to reduce the computational cost of these methods by using the localized ensemble samples to localize Be by means of a direct decomposition of the local correlation matrix C. However, the computational costs of the direct decomposition of the local correlation matrix C are still extremely high due to its high dimension. In this paper, we propose an efficient local correlation matrix decomposition approach based on the concept of alternating directions. This approach is intended to avoid direct decomposition of the correlation matrix. Instead, we first decompose the correlation matrix into 1-D correlation matrices in the three coordinate directions, then construct their empirical orthogonal function decomposition at low resolution. This procedure is followed by the 1-D spline interpolation process to transform the above decompositions to the high-resolution grid. Finally, an efficient correlation matrix decomposition is achieved by computing the very similar Kronecker product. We conducted a series of comparison experiments to illustrate the validity and accuracy of the proposed local correlation matrix decomposition approach. The effectiveness of the proposed correlation matrix decomposition approach and its efficient localization implementation of the nonlinear least-squares four-dimensional variational assimilation are further demonstrated by several groups of numerical experiments based on the Advanced Research Weather Research and Forecasting model.

  8. LOCALIZING THE RANGELAND HEALTH METHOD FOR SOUTHEASTERN ARIZONA

    EPA Science Inventory

    The interagency manual Interpreting Indicators of Rangeland Health, Version 4 (Technical Reference 1734-6) provides a method for making rangeland health assessments. The manual recommends that the rangeland health assessment approach be adapted to local conditions. This technica...

  9. Ultrasound-contrast-agent dispersion and velocity imaging for prostate cancer localization.

    PubMed

    van Sloun, Ruud Jg; Demi, Libertario; Postema, Arnoud W; de la Rosette, Jean Jmch; Wijkstra, Hessel; Mischi, Massimo

    2017-01-01

    Prostate cancer (PCa) is the second-leading cause of cancer death in men; however, reliable tools for detection and localization are still lacking. Dynamic Contrast Enhanced UltraSound (DCE-US) is a diagnostic tool that is suitable for analysis of vascularization, by imaging an intravenously injected microbubble bolus. The localization of angiogenic vascularization associated with the development of tumors is of particular interest. Recently, methods for the analysis of the bolus convective dispersion process have shown promise to localize angiogenesis. However, independent estimation of dispersion was not possible due to the ambiguity between convection and dispersion. Therefore, in this study we propose a new method that considers the vascular network as a dynamic linear system, whose impulse response can be locally identified. To this end, model-based parameter estimation is employed, that permits extraction of the apparent dispersion coefficient (D), velocity (v), and Péclet number (Pe) of the system. Clinical evaluation using data recorded from 25 patients shows that the proposed method can be applied effectively to DCE-US, and is able to locally characterize the hemodynamics, yielding promising results (receiver-operating-characteristic curve area of 0.84) for prostate cancer localization. Copyright © 2016 Elsevier B.V. All rights reserved.

  10. Petz recovery versus matrix reconstruction

    NASA Astrophysics Data System (ADS)

    Holzäpfel, Milan; Cramer, Marcus; Datta, Nilanjana; Plenio, Martin B.

    2018-04-01

    The reconstruction of the state of a multipartite quantum mechanical system represents a fundamental task in quantum information science. At its most basic, it concerns a state of a bipartite quantum system whose subsystems are subjected to local operations. We compare two different methods for obtaining the original state from the state resulting from the action of these operations. The first method involves quantum operations called Petz recovery maps, acting locally on the two subsystems. The second method is called matrix (or state) reconstruction and involves local, linear maps that are not necessarily completely positive. Moreover, we compare the quantities on which the maps employed in the two methods depend. We show that any state that admits Petz recovery also admits state reconstruction. However, the latter is successful for a strictly larger set of states. We also compare these methods in the context of a finite spin chain. Here, the state of a finite spin chain is reconstructed from the reduced states of a few neighbouring spins. In this setting, state reconstruction is the same as the matrix product operator reconstruction proposed by Baumgratz et al. [Phys. Rev. Lett. 111, 020401 (2013)]. Finally, we generalize both these methods so that they employ long-range measurements instead of relying solely on short-range correlations embodied in such local reduced states. Long-range measurements enable the reconstruction of states which cannot be reconstructed from measurements of local few-body observables alone and hereby we improve existing methods for quantum state tomography of quantum many-body systems.

  11. Graph Structure-Based Simultaneous Localization and Mapping Using a Hybrid Method of 2D Laser Scan and Monocular Camera Image in Environments with Laser Scan Ambiguity

    PubMed Central

    Oh, Taekjun; Lee, Donghwa; Kim, Hyungjin; Myung, Hyun

    2015-01-01

    Localization is an essential issue for robot navigation, allowing the robot to perform tasks autonomously. However, in environments with laser scan ambiguity, such as long corridors, the conventional SLAM (simultaneous localization and mapping) algorithms exploiting a laser scanner may not estimate the robot pose robustly. To resolve this problem, we propose a novel localization approach based on a hybrid method incorporating a 2D laser scanner and a monocular camera in the framework of a graph structure-based SLAM. 3D coordinates of image feature points are acquired through the hybrid method, with the assumption that the wall is normal to the ground and vertically flat. However, this assumption can be relieved, because the subsequent feature matching process rejects the outliers on an inclined or non-flat wall. Through graph optimization with constraints generated by the hybrid method, the final robot pose is estimated. To verify the effectiveness of the proposed method, real experiments were conducted in an indoor environment with a long corridor. The experimental results were compared with those of the conventional GMappingapproach. The results demonstrate that it is possible to localize the robot in environments with laser scan ambiguity in real time, and the performance of the proposed method is superior to that of the conventional approach. PMID:26151203

  12. Sensitivity enhancement of traveling wave MRI using free local resonators: an experimental demonstration.

    PubMed

    Zhang, Xiaoliang

    2017-04-01

    Traveling wave MR uses the far fields in signal excitation and reception, therefore its acquisition efficiency is low in contrast to the conventional near field magnetic resonance (MR). Here we show a simple and efficient method based on the local resonator to improving sensitivity of traveling wave MR technique. The proposed method utilizes a standalone or free local resonator to amplify the radio frequency magnetic fields in the interested target. The resonators have no wire connections to the MR system and thus can be conveniently placed to any place around imaging simples. A rectangular loop L/C resonator to be used as the free local resonator was tuned to the proton Larmor frequency at 7T. Traveling wave MR experiments with and without the wireless free local resonator were performed on a living rat using a 7T whole body MR scanner. The signal-to-noise ratio (SNR) or sensitivity of the images acquired was compared and evaluated. In vivo 7T imaging results show that traveling wave MR with a wireless free local resonator placed near the head of a living rat achieves at least 10-fold SNR gain over the images acquired on the same rat using conventional traveling wave MR method, i.e. imaging with no free local resonators. The proposed free local resonator technique is able to enhance the MR sensitivity and acquisition efficiency of traveling wave MR at ultrahigh fields in vivo . This method can be a simple solution to alleviating low sensitivity problem of traveling wave MRI.

  13. A Novel Locally Linear KNN Method With Applications to Visual Recognition.

    PubMed

    Liu, Qingfeng; Liu, Chengjun

    2017-09-01

    A locally linear K Nearest Neighbor (LLK) method is presented in this paper with applications to robust visual recognition. Specifically, the concept of an ideal representation is first presented, which improves upon the traditional sparse representation in many ways. The objective function based on a host of criteria for sparsity, locality, and reconstruction is then optimized to derive a novel representation, which is an approximation to the ideal representation. The novel representation is further processed by two classifiers, namely, an LLK-based classifier and a locally linear nearest mean-based classifier, for visual recognition. The proposed classifiers are shown to connect to the Bayes decision rule for minimum error. Additional new theoretical analysis is presented, such as the nonnegative constraint, the group regularization, and the computational efficiency of the proposed LLK method. New methods such as a shifted power transformation for improving reliability, a coefficients' truncating method for enhancing generalization, and an improved marginal Fisher analysis method for feature extraction are proposed to further improve visual recognition performance. Extensive experiments are implemented to evaluate the proposed LLK method for robust visual recognition. In particular, eight representative data sets are applied for assessing the performance of the LLK method for various visual recognition applications, such as action recognition, scene recognition, object recognition, and face recognition.

  14. A constructive nonlinear array (CNA) method for barely visible impact detection in composite materials

    NASA Astrophysics Data System (ADS)

    Malfense Fierro, Gian Piero; Meo, Michele

    2017-04-01

    Currently there are numerous phased array techniques such as Full Matrix Capture (FMC) and Total Focusing Method (TFM) that provide good damage assessment for composite materials. Although, linear methods struggle to evaluate and assess low levels of damage, while nonlinear methods have shown great promise in early damage detection. A sweep and subtraction evaluation method coupled with a constructive nonlinear array method (CNA) is proposed in order to assess damage specific nonlinearities, address issues with frequency selection when using nonlinear ultrasound imaging techniques and reduce equipment generated nonlinearities. These methods were evaluated using multiple excitation locations on an impacted composite panel with a complex damage (barely visible impact damage). According to various recent works, damage excitation can be accentuated by exciting at local defect resonance (LDR) frequencies; although these frequencies are not always easily determinable. The sweep methodology uses broadband excitation to determine both local defect and material resonances, by assessing local defect generated nonlinearities using a laser vibrometer it is possible to assess which frequencies excite the complex geometry of the crack. The dual effect of accurately determining local defect resonances, the use of an image subtraction method and the reduction of equipment based nonlinearities using CNA result in greater repeatability and clearer nonlinear imaging (NIM).

  15. Distribution of Localized States from Fine Analysis of Electron Spin Resonance Spectra in Organic Transistors

    NASA Astrophysics Data System (ADS)

    Matsui, Hiroyuki; Mishchenko, Andrei S.; Hasegawa, Tatsuo

    2010-02-01

    We developed a novel method for obtaining the distribution of trapped carriers over their degree of localization in organic transistors, based on the fine analysis of electron spin resonance spectra at low enough temperatures where all carriers are localized. To apply the method to pentacene thin-film transistors, we proved through continuous wave saturation experiments that all carriers are localized at below 50 K. We analyzed the spectra at 20 K and found that the major groups of traps comprise localized states having wave functions spanning around 1.5 and 5 molecules and a continuous distribution of states with spatial extent in the range between 6 and 20 molecules.

  16. Distribution of localized states from fine analysis of electron spin resonance spectra in organic transistors.

    PubMed

    Matsui, Hiroyuki; Mishchenko, Andrei S; Hasegawa, Tatsuo

    2010-02-05

    We developed a novel method for obtaining the distribution of trapped carriers over their degree of localization in organic transistors, based on the fine analysis of electron spin resonance spectra at low enough temperatures where all carriers are localized. To apply the method to pentacene thin-film transistors, we proved through continuous wave saturation experiments that all carriers are localized at below 50 K. We analyzed the spectra at 20 K and found that the major groups of traps comprise localized states having wave functions spanning around 1.5 and 5 molecules and a continuous distribution of states with spatial extent in the range between 6 and 20 molecules.

  17. Image dehazing based on non-local saturation

    NASA Astrophysics Data System (ADS)

    Wang, Linlin; Zhang, Qian; Yang, Deyun; Hou, Yingkun; He, Xiaoting

    2018-04-01

    In this paper, a method based on non-local saturation algorithm is proposed to avoid block and halo effect for single image dehazing with dark channel prior. First we convert original image from RGB color space into HSV color space with the idea of non-local method. Image saturation is weighted equally by the size of fixed window according to image resolution. Second we utilize the saturation to estimate the atmospheric light value and transmission rate. Then through the function of saturation and transmission, the haze-free image is obtained based on the atmospheric scattering model. Comparing the results of existing methods, our method can restore image color and enhance contrast. We guarantee the proposed method with quantitative and qualitative evaluation respectively. Experiments show the better visual effect with high efficiency.

  18. Local quantum thermal susceptibility

    PubMed Central

    De Pasquale, Antonella; Rossini, Davide; Fazio, Rosario; Giovannetti, Vittorio

    2016-01-01

    Thermodynamics relies on the possibility to describe systems composed of a large number of constituents in terms of few macroscopic variables. Its foundations are rooted into the paradigm of statistical mechanics, where thermal properties originate from averaging procedures which smoothen out local details. While undoubtedly successful, elegant and formally correct, this approach carries over an operational problem, namely determining the precision at which such variables are inferred, when technical/practical limitations restrict our capabilities to local probing. Here we introduce the local quantum thermal susceptibility, a quantifier for the best achievable accuracy for temperature estimation via local measurements. Our method relies on basic concepts of quantum estimation theory, providing an operative strategy to address the local thermal response of arbitrary quantum systems at equilibrium. At low temperatures, it highlights the local distinguishability of the ground state from the excited sub-manifolds, thus providing a method to locate quantum phase transitions. PMID:27681458

  19. Local quantum thermal susceptibility

    NASA Astrophysics Data System (ADS)

    de Pasquale, Antonella; Rossini, Davide; Fazio, Rosario; Giovannetti, Vittorio

    2016-09-01

    Thermodynamics relies on the possibility to describe systems composed of a large number of constituents in terms of few macroscopic variables. Its foundations are rooted into the paradigm of statistical mechanics, where thermal properties originate from averaging procedures which smoothen out local details. While undoubtedly successful, elegant and formally correct, this approach carries over an operational problem, namely determining the precision at which such variables are inferred, when technical/practical limitations restrict our capabilities to local probing. Here we introduce the local quantum thermal susceptibility, a quantifier for the best achievable accuracy for temperature estimation via local measurements. Our method relies on basic concepts of quantum estimation theory, providing an operative strategy to address the local thermal response of arbitrary quantum systems at equilibrium. At low temperatures, it highlights the local distinguishability of the ground state from the excited sub-manifolds, thus providing a method to locate quantum phase transitions.

  20. Estimation and prediction under local volatility jump-diffusion model

    NASA Astrophysics Data System (ADS)

    Kim, Namhyoung; Lee, Younhee

    2018-02-01

    Volatility is an important factor in operating a company and managing risk. In the portfolio optimization and risk hedging using the option, the value of the option is evaluated using the volatility model. Various attempts have been made to predict option value. Recent studies have shown that stochastic volatility models and jump-diffusion models reflect stock price movements accurately. However, these models have practical limitations. Combining them with the local volatility model, which is widely used among practitioners, may lead to better performance. In this study, we propose a more effective and efficient method of estimating option prices by combining the local volatility model with the jump-diffusion model and apply it using both artificial and actual market data to evaluate its performance. The calibration process for estimating the jump parameters and local volatility surfaces is divided into three stages. We apply the local volatility model, stochastic volatility model, and local volatility jump-diffusion model estimated by the proposed method to KOSPI 200 index option pricing. The proposed method displays good estimation and prediction performance.

  1. Hierarchical Leak Detection and Localization Method in Natural Gas Pipeline Monitoring Sensor Networks

    PubMed Central

    Wan, Jiangwen; Yu, Yang; Wu, Yinfeng; Feng, Renjian; Yu, Ning

    2012-01-01

    In light of the problems of low recognition efficiency, high false rates and poor localization accuracy in traditional pipeline security detection technology, this paper proposes a type of hierarchical leak detection and localization method for use in natural gas pipeline monitoring sensor networks. In the signal preprocessing phase, original monitoring signals are dealt with by wavelet transform technology to extract the single mode signals as well as characteristic parameters. In the initial recognition phase, a multi-classifier model based on SVM is constructed and characteristic parameters are sent as input vectors to the multi-classifier for initial recognition. In the final decision phase, an improved evidence combination rule is designed to integrate initial recognition results for final decisions. Furthermore, a weighted average localization algorithm based on time difference of arrival is introduced for determining the leak point’s position. Experimental results illustrate that this hierarchical pipeline leak detection and localization method could effectively improve the accuracy of the leak point localization and reduce the undetected rate as well as false alarm rate. PMID:22368464

  2. Hierarchical leak detection and localization method in natural gas pipeline monitoring sensor networks.

    PubMed

    Wan, Jiangwen; Yu, Yang; Wu, Yinfeng; Feng, Renjian; Yu, Ning

    2012-01-01

    In light of the problems of low recognition efficiency, high false rates and poor localization accuracy in traditional pipeline security detection technology, this paper proposes a type of hierarchical leak detection and localization method for use in natural gas pipeline monitoring sensor networks. In the signal preprocessing phase, original monitoring signals are dealt with by wavelet transform technology to extract the single mode signals as well as characteristic parameters. In the initial recognition phase, a multi-classifier model based on SVM is constructed and characteristic parameters are sent as input vectors to the multi-classifier for initial recognition. In the final decision phase, an improved evidence combination rule is designed to integrate initial recognition results for final decisions. Furthermore, a weighted average localization algorithm based on time difference of arrival is introduced for determining the leak point's position. Experimental results illustrate that this hierarchical pipeline leak detection and localization method could effectively improve the accuracy of the leak point localization and reduce the undetected rate as well as false alarm rate.

  3. Local Composite Quantile Regression Smoothing for Harris Recurrent Markov Processes

    PubMed Central

    Li, Degui; Li, Runze

    2016-01-01

    In this paper, we study the local polynomial composite quantile regression (CQR) smoothing method for the nonlinear and nonparametric models under the Harris recurrent Markov chain framework. The local polynomial CQR regression method is a robust alternative to the widely-used local polynomial method, and has been well studied in stationary time series. In this paper, we relax the stationarity restriction on the model, and allow that the regressors are generated by a general Harris recurrent Markov process which includes both the stationary (positive recurrent) and nonstationary (null recurrent) cases. Under some mild conditions, we establish the asymptotic theory for the proposed local polynomial CQR estimator of the mean regression function, and show that the convergence rate for the estimator in nonstationary case is slower than that in stationary case. Furthermore, a weighted type local polynomial CQR estimator is provided to improve the estimation efficiency, and a data-driven bandwidth selection is introduced to choose the optimal bandwidth involved in the nonparametric estimators. Finally, we give some numerical studies to examine the finite sample performance of the developed methodology and theory. PMID:27667894

  4. Evaluation of local site effect from microtremor measurements in Babol City, Iran

    NASA Astrophysics Data System (ADS)

    Rezaei, Sadegh; Choobbasti, Asskar Janalizadeh

    2018-03-01

    Every year, numerous casualties and a large deal of financial losses are incurred due to earthquake events. The losses incurred by an earthquake vary depending on local site effect. Therefore, in order to conquer drastic effects of an earthquake, one should evaluate urban districts in terms of the local site effect. One of the methods for evaluating the local site effect is microtremor measurement and analysis. Aiming at evaluation of local site effect across the city of Babol, the study area was gridded and microtremor measurements were performed with an appropriate distribution. The acquired data was analyzed through the horizontal-to-vertical noise ratio (HVNR) method, and fundamental frequency and associated amplitude of the H/V peak were obtained. The results indicate that fundamental frequency of the study area is generally lower than 1.25 Hz, which is acceptably in agreement with the findings of previous studies. Also, in order to constrain and validate the seismostratigraphic model obtained with this method, the results were compared with geotechnical, geological, and seismic data. Comparing the results of different methods, it was observed that the presented geophysical method can successfully determine the values of fundamental frequency across the study area as well as local site effect. Using the data obtained from the analysis of microtremor, a microzonation map of fundamental frequency across the city of Babol was prepared. This map has numerous applications in designing high-rise building and urban development plans.

  5. Supplementary routes to local anaesthesia.

    PubMed

    Meechan, J G

    2002-11-01

    The satisfactory provision of many dental treatments, particularly endodontics, relies on achieving excellent pain control. Unfortunately, the administration of a local anaesthetic solution does not always produce satisfactory anaesthesia of the dental pulp. This may be distressing for both patient and operator. Fortunately, failure of local anaesthetic injections can be overcome. This is often achieved by using alternative routes of approach for subsequent injections. Nerves such as the inferior alveolar nerve can be anaesthetized by a variety of block methods. However, techniques of anaesthesia other than the standard infiltration and regional block injections may be employed successfully when these former methods have failed to produce adequate pain control. This paper describes some supplementary local anaesthetic techniques that may be used to achieve pulpal anaesthesia for endodontic procedures when conventional approaches have failed. Although some of these techniques can be used as the primary form of anaesthesia, these are normally employed as 'back-up'. The methods described are intraligamentary (periodontal ligament) injections, intraosseous anaesthesia and the intrapulpal approach. The factors that influence the success of these methods and the advantages and disadvantages of each technique are discussed. The advent of new instrumentation, which permits the slow delivery of local anaesthetic solution has led to the development of novel methods of anaesthesia in dentistry. These new approaches are discussed.

  6. Local spatiotemporal time-frequency peak filtering method for seismic random noise reduction

    NASA Astrophysics Data System (ADS)

    Liu, Yanping; Dang, Bo; Li, Yue; Lin, Hongbo

    2014-12-01

    To achieve a higher level of seismic random noise suppression, the Radon transform has been adopted to implement spatiotemporal time-frequency peak filtering (TFPF) in our previous studies. Those studies involved performing TFPF in full-aperture Radon domain, including linear Radon and parabolic Radon. Although the superiority of this method to the conventional TFPF has been tested through processing on synthetic seismic models and field seismic data, there are still some limitations in the method. Both full-aperture linear Radon and parabolic Radon are applicable and effective for some relatively simple situations (e.g., curve reflection events with regular geometry) but inapplicable for complicated situations such as reflection events with irregular shapes, or interlaced events with quite different slope or curvature parameters. Therefore, a localized approach to the application of the Radon transform must be applied. It would serve the filter method better by adapting the transform to the local character of the data variations. In this article, we propose an idea that adopts the local Radon transform referred to as piecewise full-aperture Radon to realize spatiotemporal TFPF, called local spatiotemporal TFPF. Through experiments on synthetic seismic models and field seismic data, this study demonstrates the advantage of our method in seismic random noise reduction and reflection event recovery for relatively complicated situations of seismic data.

  7. Local CC2 response method based on the Laplace transform: analytic energy gradients for ground and excited states.

    PubMed

    Ledermüller, Katrin; Schütz, Martin

    2014-04-28

    A multistate local CC2 response method for the calculation of analytic energy gradients with respect to nuclear displacements is presented for ground and electronically excited states. The gradient enables the search for equilibrium geometries of extended molecular systems. Laplace transform is used to partition the eigenvalue problem in order to obtain an effective singles eigenvalue problem and adaptive, state-specific local approximations. This leads to an approximation in the energy Lagrangian, which however is shown (by comparison with the corresponding gradient method without Laplace transform) to be of no concern for geometry optimizations. The accuracy of the local approximation is tested and the efficiency of the new code is demonstrated by application calculations devoted to a photocatalytic decarboxylation process of present interest.

  8. Ecological risk assessment in legislation on contaminated soil in The Netherlands.

    PubMed

    Boekhold, Alexandra E

    2008-12-01

    Recently the Dutch soil policy was revised including new rules for the relocation of contaminated soil and dredged soil material. With these rules, new methods for ecotoxicological risk assessment were implemented. One of the new methods is the assessment of the local toxic pressure of mixtures, also known as the ms-PAF- method, based on the Species Sensitivity Distribution concept. The ms-PAF method is applied for risk assessment of spreading of dredged soil material on adjacent land. Its application will possibly be extended to the derivation of local soil quality standards relevant in the context of soil relocation. The application of the local toxic pressure will probably increase the reuse of contaminated soil and dredged soil material and hence will reduce the amounts considered to be unfit for use. With this method, local ecological risk limits are derived using pore water concentrations and effects on water organisms. Pore water concentrations are subsequently transferred to total soil concentrations using empirical relationships. The methodology does not impose upper limits for total soil concentrations. In soils with a high sorption capacity, total soil concentrations that are considered to be acceptable may be several times higher than the current Dutch intervention values. The possible introduction of the ms-PAF method will open the door to local soil relocation with soils containing large amounts of (semi-permanently soil bound) contaminants. Since the ms-PAF method is not yet properly validated, the lack of evidence of ecological effects using models like the ms-PAF method cannot be regarded as an indication for the absence of effects in reality. The Dutch soil quality decree would gain environmental ambition when the ms-PAF method was combined with a realistic upper limit on total soil concentrations. This would prevent contamination of land by means of soil relocation.

  9. Evaluation of methods to produce an image library for automatic patient model localization for dose mapping during fluoroscopically guided procedures

    NASA Astrophysics Data System (ADS)

    Kilian-Meneghin, Josh; Xiong, Z.; Rudin, S.; Oines, A.; Bednarek, D. R.

    2017-03-01

    The purpose of this work is to evaluate methods for producing a library of 2D-radiographic images to be correlated to clinical images obtained during a fluoroscopically-guided procedure for automated patient-model localization. The localization algorithm will be used to improve the accuracy of the skin-dose map superimposed on the 3D patient- model of the real-time Dose-Tracking-System (DTS). For the library, 2D images were generated from CT datasets of the SK-150 anthropomorphic phantom using two methods: Schmid's 3D-visualization tool and Plastimatch's digitally-reconstructed-radiograph (DRR) code. Those images, as well as a standard 2D-radiographic image, were correlated to a 2D-fluoroscopic image of a phantom, which represented the clinical-fluoroscopic image, using the Corr2 function in Matlab. The Corr2 function takes two images and outputs the relative correlation between them, which is fed into the localization algorithm. Higher correlation means better alignment of the 3D patient-model with the patient image. In this instance, it was determined that the localization algorithm will succeed when Corr2 returns a correlation of at least 50%. The 3D-visualization tool images returned 55-80% correlation relative to the fluoroscopic-image, which was comparable to the correlation for the radiograph. The DRR images returned 61-90% correlation, again comparable to the radiograph. Both methods prove to be sufficient for the localization algorithm and can be produced quickly; however, the DRR method produces more accurate grey-levels. Using the DRR code, a library at varying angles can be produced for the localization algorithm.

  10. Exploring local regularities for 3D object recognition

    NASA Astrophysics Data System (ADS)

    Tian, Huaiwen; Qin, Shengfeng

    2016-11-01

    In order to find better simplicity measurements for 3D object recognition, a new set of local regularities is developed and tested in a stepwise 3D reconstruction method, including localized minimizing standard deviation of angles(L-MSDA), localized minimizing standard deviation of segment magnitudes(L-MSDSM), localized minimum standard deviation of areas of child faces (L-MSDAF), localized minimum sum of segment magnitudes of common edges (L-MSSM), and localized minimum sum of areas of child face (L-MSAF). Based on their effectiveness measurements in terms of form and size distortions, it is found that when two local regularities: L-MSDA and L-MSDSM are combined together, they can produce better performance. In addition, the best weightings for them to work together are identified as 10% for L-MSDSM and 90% for L-MSDA. The test results show that the combined usage of L-MSDA and L-MSDSM with identified weightings has a potential to be applied in other optimization based 3D recognition methods to improve their efficacy and robustness.

  11. Effective representation of amide III, II, I, and A modes on local vibrational modes: Analysis of ab initio quantum calculation results.

    PubMed

    Hahn, Seungsoo

    2016-10-28

    The Hamiltonian matrix for the first excited vibrational states of a protein can be effectively represented by local vibrational modes constituting amide III, II, I, and A modes to simulate various vibrational spectra. Methods for obtaining the Hamiltonian matrix from ab initio quantum calculation results are discussed, where the methods consist of three steps: selection of local vibrational mode coordinates, calculation of a reduced Hessian matrix, and extraction of the Hamiltonian matrix from the Hessian matrix. We introduce several methods for each step. The methods were assessed based on the density functional theory calculation results of 24 oligopeptides with four different peptide lengths and six different secondary structures. The completeness of a Hamiltonian matrix represented in the reduced local mode space is improved by adopting a specific atom group for each amide mode and reducing the effect of ignored local modes. The calculation results are also compared to previous models using C=O stretching vibration and transition dipole couplings. We found that local electric transition dipole moments of the amide modes are mainly bound on the local peptide planes. Their direction and magnitude are well conserved except amide A modes, which show large variation. Contrary to amide I modes, the vibrational coupling constants of amide III, II, and A modes obtained by analysis of a dipeptide are not transferable to oligopeptides with the same secondary conformation because coupling constants are affected by the surrounding atomic environment.

  12. An iterative method for the localization of a neutron source in a large box (container)

    NASA Astrophysics Data System (ADS)

    Dubinski, S.; Presler, O.; Alfassi, Z. B.

    2007-12-01

    The localization of an unknown neutron source in a bulky box was studied. This can be used for the inspection of cargo, to prevent the smuggling of neutron and α emitters. It is important to localize the source from the outside for safety reasons. Source localization is necessary in order to determine its activity. A previous study showed that, by using six detectors, three on each parallel face of the box (460×420×200 mm 3), the location of the source can be found with an average distance of 4.73 cm between the real source position and the calculated one and a maximal distance of about 9 cm. Accuracy was improved in this work by applying an iteration method based on four fixed detectors and the successive iteration of positioning of an external calibrating source. The initial positioning of the calibrating source is the plane of detectors 1 and 2. This method finds the unknown source location with an average distance of 0.78 cm between the real source position and the calculated one and a maximum distance of 3.66 cm for the same box. For larger boxes, localization without iterations requires an increase in the number of detectors, while localization with iterations requires only an increase in the number of iteration steps. In addition to source localization, two methods for determining the activity of the unknown source were also studied.

  13. Fast words boundaries localization in text fields for low quality document images

    NASA Astrophysics Data System (ADS)

    Ilin, Dmitry; Novikov, Dmitriy; Polevoy, Dmitry; Nikolaev, Dmitry

    2018-04-01

    The paper examines the problem of word boundaries precise localization in document text zones. Document processing on a mobile device consists of document localization, perspective correction, localization of individual fields, finding words in separate zones, segmentation and recognition. While capturing an image with a mobile digital camera under uncontrolled capturing conditions, digital noise, perspective distortions or glares may occur. Further document processing gets complicated because of its specifics: layout elements, complex background, static text, document security elements, variety of text fonts. However, the problem of word boundaries localization has to be solved at runtime on mobile CPU with limited computing capabilities under specified restrictions. At the moment, there are several groups of methods optimized for different conditions. Methods for the scanned printed text are quick but limited only for images of high quality. Methods for text in the wild have an excessively high computational complexity, thus, are hardly suitable for running on mobile devices as part of the mobile document recognition system. The method presented in this paper solves a more specialized problem than the task of finding text on natural images. It uses local features, a sliding window and a lightweight neural network in order to achieve an optimal algorithm speed-precision ratio. The duration of the algorithm is 12 ms per field running on an ARM processor of a mobile device. The error rate for boundaries localization on a test sample of 8000 fields is 0.3

  14. Localization of U(1) gauge vector field on flat branes with five-dimension (asymptotic) AdS5 spacetime

    NASA Astrophysics Data System (ADS)

    Zhao, Zhen-Hua; Xie, Qun-Ying

    2018-05-01

    In order to localize U(1) gauge vector field on Randall-Sundrum-like braneworld model with infinite extra dimension, we propose a new kind of non-minimal coupling between the U(1) gauge field and the gravity. We propose three kinds of coupling methods and they all support the localization of zero mode. In addition, one of them can support the localization of massive modes. Moreover, the massive tachyonic modes can be excluded. And our method can be used not only in the thin braneword models but also in the thick ones.

  15. A second order discontinuous Galerkin fast sweeping method for Eikonal equations

    NASA Astrophysics Data System (ADS)

    Li, Fengyan; Shu, Chi-Wang; Zhang, Yong-Tao; Zhao, Hongkai

    2008-09-01

    In this paper, we construct a second order fast sweeping method with a discontinuous Galerkin (DG) local solver for computing viscosity solutions of a class of static Hamilton-Jacobi equations, namely the Eikonal equations. Our piecewise linear DG local solver is built on a DG method developed recently [Y. Cheng, C.-W. Shu, A discontinuous Galerkin finite element method for directly solving the Hamilton-Jacobi equations, Journal of Computational Physics 223 (2007) 398-415] for the time-dependent Hamilton-Jacobi equations. The causality property of Eikonal equations is incorporated into the design of this solver. The resulting local nonlinear system in the Gauss-Seidel iterations is a simple quadratic system and can be solved explicitly. The compactness of the DG method and the fast sweeping strategy lead to fast convergence of the new scheme for Eikonal equations. Extensive numerical examples verify efficiency, convergence and second order accuracy of the proposed method.

  16. Remotely actuated localized pressure and heat apparatus and method of use

    NASA Technical Reports Server (NTRS)

    Merret, John B. (Inventor); Taylor, DeVor R. (Inventor); Wheeler, Mark M. (Inventor); Gale, Dan R. (Inventor)

    2004-01-01

    Apparatus and method for the use of a remotely actuated localized pressure and heat apparatus for the consolidation and curing of fiber elements in, structures. The apparatus includes members for clamping the desired portion of the fiber elements to be joined, pressure members and/or heat members. The method is directed to the application and use of the apparatus.

  17. Active Electro-Location of Objects in the Underwater Environment Based on the Mixed Polarization Multiple Signal Classification Algorithm

    PubMed Central

    Guo, Lili; Qi, Junwei; Xue, Wei

    2018-01-01

    This article proposes a novel active localization method based on the mixed polarization multiple signal classification (MP-MUSIC) algorithm for positioning a metal target or an insulator target in the underwater environment by using a uniform circular antenna (UCA). The boundary element method (BEM) is introduced to analyze the boundary of the target by use of a matrix equation. In this method, an electric dipole source as a part of the locating system is set perpendicularly to the plane of the UCA. As a result, the UCA can only receive the induction field of the target. The potential of each electrode of the UCA is used as spatial-temporal localization data, and it does not need to obtain the field component in each direction compared with the conventional fields-based localization method, which can be easily implemented in practical engineering applications. A simulation model and a physical experiment are constructed. The simulation and the experiment results provide accurate positioning performance, with the help of verifying the effectiveness of the proposed localization method in underwater target locating. PMID:29439495

  18. Robust finger vein ROI localization based on flexible segmentation.

    PubMed

    Lu, Yu; Xie, Shan Juan; Yoon, Sook; Yang, Jucheng; Park, Dong Sun

    2013-10-24

    Finger veins have been proved to be an effective biometric for personal identification in the recent years. However, finger vein images are easily affected by influences such as image translation, orientation, scale, scattering, finger structure, complicated background, uneven illumination, and collection posture. All these factors may contribute to inaccurate region of interest (ROI) definition, and so degrade the performance of finger vein identification system. To improve this problem, in this paper, we propose a finger vein ROI localization method that has high effectiveness and robustness against the above factors. The proposed method consists of a set of steps to localize ROIs accurately, namely segmentation, orientation correction, and ROI detection. Accurate finger region segmentation and correct calculated orientation can support each other to produce higher accuracy in localizing ROIs. Extensive experiments have been performed on the finger vein image database, MMCBNU_6000, to verify the robustness of the proposed method. The proposed method shows the segmentation accuracy of 100%. Furthermore, the average processing time of the proposed method is 22 ms for an acquired image, which satisfies the criterion of a real-time finger vein identification system.

  19. Robust Finger Vein ROI Localization Based on Flexible Segmentation

    PubMed Central

    Lu, Yu; Xie, Shan Juan; Yoon, Sook; Yang, Jucheng; Park, Dong Sun

    2013-01-01

    Finger veins have been proved to be an effective biometric for personal identification in the recent years. However, finger vein images are easily affected by influences such as image translation, orientation, scale, scattering, finger structure, complicated background, uneven illumination, and collection posture. All these factors may contribute to inaccurate region of interest (ROI) definition, and so degrade the performance of finger vein identification system. To improve this problem, in this paper, we propose a finger vein ROI localization method that has high effectiveness and robustness against the above factors. The proposed method consists of a set of steps to localize ROIs accurately, namely segmentation, orientation correction, and ROI detection. Accurate finger region segmentation and correct calculated orientation can support each other to produce higher accuracy in localizing ROIs. Extensive experiments have been performed on the finger vein image database, MMCBNU_6000, to verify the robustness of the proposed method. The proposed method shows the segmentation accuracy of 100%. Furthermore, the average processing time of the proposed method is 22 ms for an acquired image, which satisfies the criterion of a real-time finger vein identification system. PMID:24284769

  20. Spreading to localized targets in complex networks

    NASA Astrophysics Data System (ADS)

    Sun, Ye; Ma, Long; Zeng, An; Wang, Wen-Xu

    2016-12-01

    As an important type of dynamics on complex networks, spreading is widely used to model many real processes such as the epidemic contagion and information propagation. One of the most significant research questions in spreading is to rank the spreading ability of nodes in the network. To this end, substantial effort has been made and a variety of effective methods have been proposed. These methods usually define the spreading ability of a node as the number of finally infected nodes given that the spreading is initialized from the node. However, in many real cases such as advertising and news propagation, the spreading only aims to cover a specific group of nodes. Therefore, it is necessary to study the spreading ability of nodes towards localized targets in complex networks. In this paper, we propose a reversed local path algorithm for this problem. Simulation results show that our method outperforms the existing methods in identifying the influential nodes with respect to these localized targets. Moreover, the influential spreaders identified by our method can effectively avoid infecting the non-target nodes in the spreading process.

  1. Spatial sparsity based indoor localization in wireless sensor network for assistive healthcare.

    PubMed

    Pourhomayoun, Mohammad; Jin, Zhanpeng; Fowler, Mark

    2012-01-01

    Indoor localization is one of the key topics in the area of wireless networks with increasing applications in assistive healthcare, where tracking the position and actions of the patient or elderly are required for medical observation or accident prevention. Most of the common indoor localization methods are based on estimating one or more location-dependent signal parameters like TOA, AOA or RSS. However, some difficulties and challenges caused by the complex scenarios within a closed space significantly limit the applicability of those existing approaches in an indoor assistive environment, such as the well-known multipath effect. In this paper, we develop a new one-stage localization method based on spatial sparsity of the x-y plane. In this method, we directly estimate the location of the emitter without going through the intermediate stage of TOA or signal strength estimation. We evaluate the performance of the proposed method using Monte Carlo simulation. The results show that the proposed method is (i) very accurate even with a small number of sensors and (ii) very effective in addressing the multi-path issues.

  2. Damage localization by statistical evaluation of signal-processed mode shapes

    NASA Astrophysics Data System (ADS)

    Ulriksen, M. D.; Damkilde, L.

    2015-07-01

    Due to their inherent, ability to provide structural information on a local level, mode shapes and t.lieir derivatives are utilized extensively for structural damage identification. Typically, more or less advanced mathematical methods are implemented to identify damage-induced discontinuities in the spatial mode shape signals, hereby potentially facilitating damage detection and/or localization. However, by being based on distinguishing damage-induced discontinuities from other signal irregularities, an intrinsic deficiency in these methods is the high sensitivity towards measurement, noise. The present, article introduces a damage localization method which, compared to the conventional mode shape-based methods, has greatly enhanced robustness towards measurement, noise. The method is based on signal processing of spatial mode shapes by means of continuous wavelet, transformation (CWT) and subsequent, application of a generalized discrete Teager-Kaiser energy operator (GDTKEO) to identify damage-induced mode shape discontinuities. In order to evaluate whether the identified discontinuities are in fact, damage-induced, outlier analysis of principal components of the signal-processed mode shapes is conducted on the basis of T2-statistics. The proposed method is demonstrated in the context, of analytical work with a free-vibrating Euler-Bernoulli beam under noisy conditions.

  3. Slant correction for handwritten English documents

    NASA Astrophysics Data System (ADS)

    Shridhar, Malayappan; Kimura, Fumitaka; Ding, Yimei; Miller, John W. V.

    2004-12-01

    Optical character recognition of machine-printed documents is an effective means for extracting textural material. While the level of effectiveness for handwritten documents is much poorer, progress is being made in more constrained applications such as personal checks and postal addresses. In these applications a series of steps is performed for recognition beginning with removal of skew and slant. Slant is a characteristic unique to the writer and varies from writer to writer in which characters are tilted some amount from vertical. The second attribute is the skew that arises from the inability of the writer to write on a horizontal line. Several methods have been proposed and discussed for average slant estimation and correction in the earlier papers. However, analysis of many handwritten documents reveals that slant is a local property and slant varies even within a word. The use of an average slant for the entire word often results in overestimation or underestimation of the local slant. This paper describes three methods for local slant estimation, namely the simple iterative method, high-speed iterative method, and the 8-directional chain code method. The experimental results show that the proposed methods can estimate and correct local slant more effectively than the average slant correction.

  4. Local motion compensation in image sequences degraded by atmospheric turbulence: a comparative analysis of optical flow vs. block matching methods

    NASA Astrophysics Data System (ADS)

    Huebner, Claudia S.

    2016-10-01

    As a consequence of fluctuations in the index of refraction of the air, atmospheric turbulence causes scintillation, spatial and temporal blurring as well as global and local image motion creating geometric distortions. To mitigate these effects many different methods have been proposed. Global as well as local motion compensation in some form or other constitutes an integral part of many software-based approaches. For the estimation of motion vectors between consecutive frames simple methods like block matching are preferable to more complex algorithms like optical flow, at least when challenged with near real-time requirements. However, the processing power of commercially available computers continues to increase rapidly and the more powerful optical flow methods have the potential to outperform standard block matching methods. Therefore, in this paper three standard optical flow algorithms, namely Horn-Schunck (HS), Lucas-Kanade (LK) and Farnebäck (FB), are tested for their suitability to be employed for local motion compensation as part of a turbulence mitigation system. Their qualitative performance is evaluated and compared with that of three standard block matching methods, namely Exhaustive Search (ES), Adaptive Rood Pattern Search (ARPS) and Correlation based Search (CS).

  5. Ligand Binding Site Detection by Local Structure Alignment and Its Performance Complementarity

    PubMed Central

    Lee, Hui Sun; Im, Wonpil

    2013-01-01

    Accurate determination of potential ligand binding sites (BS) is a key step for protein function characterization and structure-based drug design. Despite promising results of template-based BS prediction methods using global structure alignment (GSA), there is a room to improve the performance by properly incorporating local structure alignment (LSA) because BS are local structures and often similar for proteins with dissimilar global folds. We present a template-based ligand BS prediction method using G-LoSA, our LSA tool. A large benchmark set validation shows that G-LoSA predicts drug-like ligands’ positions in single-chain protein targets more precisely than TM-align, a GSA-based method, while the overall success rate of TM-align is better. G-LoSA is particularly efficient for accurate detection of local structures conserved across proteins with diverse global topologies. Recognizing the performance complementarity of G-LoSA to TM-align and a non-template geometry-based method, fpocket, a robust consensus scoring method, CMCS-BSP (Complementary Methods and Consensus Scoring for ligand Binding Site Prediction), is developed and shows improvement on prediction accuracy. The G-LoSA source code is freely available at http://im.bioinformatics.ku.edu/GLoSA. PMID:23957286

  6. Propagation of Gaussian wave packets in complex media and application to fracture characterization

    NASA Astrophysics Data System (ADS)

    Ding, Yinshuai; Zheng, Yingcai; Zhou, Hua-Wei; Howell, Michael; Hu, Hao; Zhang, Yu

    2017-08-01

    Knowledge of the subsurface fracture networks is critical in probing the tectonic stress states and flow of fluids in reservoirs containing fractures. We propose to characterize fractures using scattered seismic data, based on the theory of local plane-wave multiple scattering in a fractured medium. We construct a localized directional wave packet using point sources on the surface and propagate it toward the targeted subsurface fractures. The wave packet behaves as a local plane wave when interacting with the fractures. The interaction produces multiple scattering of the wave packet that eventually travels up to the surface receivers. The propagation direction and amplitude of the multiply scattered wave can be used to characterize fracture density, orientation and compliance. Two key aspects in this characterization process are the spatial localization and directionality of the wave packet. Here we first show the physical behaviour of a new localized wave, known as the Gaussian Wave Packet (GWP), by examining its analytical solution originally formulated for a homogenous medium. We then use a numerical finite-difference time-domain (FDTD) method to study its propagation behaviour in heterogeneous media. We find that a GWP can still be localized and directional in space even over a large propagation distance in heterogeneous media. We then propose a method to decompose the recorded seismic wavefield into GWPs based on the reverse-time concept. This method enables us to create a virtually recorded seismic data using field shot gathers, as if the source were an incident GWP. Finally, we demonstrate the feasibility of using GWPs for fracture characterization using three numerical examples. For a medium containing fractures, we can reliably invert for the local parameters of multiple fracture sets. Differing from conventional seismic imaging such as migration methods, our fracture characterization method is less sensitive to errors in the background velocity model. For a layered medium containing fractures, our method can correctly recover the fracture density even with an inaccurate velocity model.

  7. Prostate cancer localization with multispectral MRI using cost-sensitive support vector machines and conditional random fields.

    PubMed

    Artan, Yusuf; Haider, Masoom A; Langer, Deanna L; van der Kwast, Theodorus H; Evans, Andrew J; Yang, Yongyi; Wernick, Miles N; Trachtenberg, John; Yetik, Imam Samil

    2010-09-01

    Prostate cancer is a leading cause of cancer death for men in the United States. Fortunately, the survival rate for early diagnosed patients is relatively high. Therefore, in vivo imaging plays an important role for the detection and treatment of the disease. Accurate prostate cancer localization with noninvasive imaging can be used to guide biopsy, radiotherapy, and surgery as well as to monitor disease progression. Magnetic resonance imaging (MRI) performed with an endorectal coil provides higher prostate cancer localization accuracy, when compared to transrectal ultrasound (TRUS). However, in general, a single type of MRI is not sufficient for reliable tumor localization. As an alternative, multispectral MRI, i.e., the use of multiple MRI-derived datasets, has emerged as a promising noninvasive imaging technique for the localization of prostate cancer; however almost all studies are with human readers. There is a significant inter and intraobserver variability for human readers, and it is substantially difficult for humans to analyze the large dataset of multispectral MRI. To solve these problems, this study presents an automated localization method using cost-sensitive support vector machines (SVMs) and shows that this method results in improved localization accuracy than classical SVM. Additionally, we develop a new segmentation method by combining conditional random fields (CRF) with a cost-sensitive framework and show that our method further improves cost-sensitive SVM results by incorporating spatial information. We test SVM, cost-sensitive SVM, and the proposed cost-sensitive CRF on multispectral MRI datasets acquired from 21 biopsy-confirmed cancer patients. Our results show that multispectral MRI helps to increase the accuracy of prostate cancer localization when compared to single MR images; and that using advanced methods such as cost-sensitive SVM as well as the proposed cost-sensitive CRF can boost the performance significantly when compared to SVM.

  8. Bayesian random local clocks, or one rate to rule them all

    PubMed Central

    2010-01-01

    Background Relaxed molecular clock models allow divergence time dating and "relaxed phylogenetic" inference, in which a time tree is estimated in the face of unequal rates across lineages. We present a new method for relaxing the assumption of a strict molecular clock using Markov chain Monte Carlo to implement Bayesian modeling averaging over random local molecular clocks. The new method approaches the problem of rate variation among lineages by proposing a series of local molecular clocks, each extending over a subregion of the full phylogeny. Each branch in a phylogeny (subtending a clade) is a possible location for a change of rate from one local clock to a new one. Thus, including both the global molecular clock and the unconstrained model results, there are a total of 22n-2 possible rate models available for averaging with 1, 2, ..., 2n - 2 different rate categories. Results We propose an efficient method to sample this model space while simultaneously estimating the phylogeny. The new method conveniently allows a direct test of the strict molecular clock, in which one rate rules them all, against a large array of alternative local molecular clock models. We illustrate the method's utility on three example data sets involving mammal, primate and influenza evolution. Finally, we explore methods to visualize the complex posterior distribution that results from inference under such models. Conclusions The examples suggest that large sequence datasets may only require a small number of local molecular clocks to reconcile their branch lengths with a time scale. All of the analyses described here are implemented in the open access software package BEAST 1.5.4 (http://beast-mcmc.googlecode.com/). PMID:20807414

  9. A Mobile Anchor Assisted Localization Algorithm Based on Regular Hexagon in Wireless Sensor Networks

    PubMed Central

    Rodrigues, Joel J. P. C.

    2014-01-01

    Localization is one of the key technologies in wireless sensor networks (WSNs), since it provides fundamental support for many location-aware protocols and applications. Constraints of cost and power consumption make it infeasible to equip each sensor node in the network with a global position system (GPS) unit, especially for large-scale WSNs. A promising method to localize unknown nodes is to use several mobile anchors which are equipped with GPS units moving among unknown nodes and periodically broadcasting their current locations to help nearby unknown nodes with localization. This paper proposes a mobile anchor assisted localization algorithm based on regular hexagon (MAALRH) in two-dimensional WSNs, which can cover the whole monitoring area with a boundary compensation method. Unknown nodes calculate their positions by using trilateration. We compare the MAALRH with HILBERT, CIRCLES, and S-CURVES algorithms in terms of localization ratio, localization accuracy, and path length. Simulations show that the MAALRH can achieve high localization ratio and localization accuracy when the communication range is not smaller than the trajectory resolution. PMID:25133212

  10. Assessing climate impacts of planning policies-An estimation for the urban region of Leipzig (Germany)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schwarz, Nina, E-mail: nina.schwarz@ufz.de; Bauer, Annette, E-mail: annette.bauer@ufz.de; Haase, Dagmar, E-mail: dagmar.haase@ufz.d

    2011-03-15

    Local climate regulation by urban green areas is an important urban ecosystem service, as it reduces the extent of the urban heat island and therefore enhances quality of life. Local and regional planning policies can control land use changes in an urban region, which in turn alter local climate regulation. Thus, this paper describes a method for estimating the impacts of current land uses as well as local and regional planning policies on local climate regulation, using evapotranspiration and land surface emissivity as indicators. This method can be used by practitioners to evaluate their policies. An application of this methodmore » is demonstrated for the case study Leipzig (Germany). Results for six selected planning policies in Leipzig indicate their distinct impacts on climate regulation and especially the role of their spatial extent. The proposed method was found to easily produce a qualitative assessment of impacts of planning policies on climate regulation.« less

  11. Study on Finite Element Model Updating in Highway Bridge Static Loading Test Using Spatially-Distributed Optical Fiber Sensors

    PubMed Central

    Wu, Bitao; Lu, Huaxi; Chen, Bo; Gao, Zhicheng

    2017-01-01

    A finite model updating method that combines dynamic-static long-gauge strain responses is proposed for highway bridge static loading tests. For this method, the objective function consisting of static long-gauge stains and the first order modal macro-strain parameter (frequency) is established, wherein the local bending stiffness, density and boundary conditions of the structures are selected as the design variables. The relationship between the macro-strain and local element stiffness was studied first. It is revealed that the macro-strain is inversely proportional to the local stiffness covered by the long-gauge strain sensor. This corresponding relation is important for the modification of the local stiffness based on the macro-strain. The local and global parameters can be simultaneously updated. Then, a series of numerical simulation and experiments were conducted to verify the effectiveness of the proposed method. The results show that the static deformation, macro-strain and macro-strain modal can be predicted well by using the proposed updating model. PMID:28753912

  12. Measuring true localization accuracy in super resolution microscopy with DNA-origami nanostructures

    NASA Astrophysics Data System (ADS)

    Reuss, Matthias; Fördős, Ferenc; Blom, Hans; Öktem, Ozan; Högberg, Björn; Brismar, Hjalmar

    2017-02-01

    A common method to assess the performance of (super resolution) microscopes is to use the localization precision of emitters as an estimate for the achieved resolution. Naturally, this is widely used in super resolution methods based on single molecule stochastic switching. This concept suffers from the fact that it is hard to calibrate measures against a real sample (a phantom), because true absolute positions of emitters are almost always unknown. For this reason, resolution estimates are potentially biased in an image since one is blind to true position accuracy, i.e. deviation in position measurement from true positions. We have solved this issue by imaging nanorods fabricated with DNA-origami. The nanorods used are designed to have emitters attached at each end in a well-defined and highly conserved distance. These structures are widely used to gauge localization precision. Here, we additionally determined the true achievable localization accuracy and compared this figure of merit to localization precision values for two common super resolution microscope methods STED and STORM.

  13. Study on Finite Element Model Updating in Highway Bridge Static Loading Test Using Spatially-Distributed Optical Fiber Sensors.

    PubMed

    Wu, Bitao; Lu, Huaxi; Chen, Bo; Gao, Zhicheng

    2017-07-19

    A finite model updating method that combines dynamic-static long-gauge strain responses is proposed for highway bridge static loading tests. For this method, the objective function consisting of static long-gauge stains and the first order modal macro-strain parameter (frequency) is established, wherein the local bending stiffness, density and boundary conditions of the structures are selected as the design variables. The relationship between the macro-strain and local element stiffness was studied first. It is revealed that the macro-strain is inversely proportional to the local stiffness covered by the long-gauge strain sensor. This corresponding relation is important for the modification of the local stiffness based on the macro-strain. The local and global parameters can be simultaneously updated. Then, a series of numerical simulation and experiments were conducted to verify the effectiveness of the proposed method. The results show that the static deformation, macro-strain and macro-strain modal can be predicted well by using the proposed updating model.

  14. Localization of multiple defects using the compact phased array (CPA) method

    NASA Astrophysics Data System (ADS)

    Senyurek, Volkan Y.; Baghalian, Amin; Tashakori, Shervin; McDaniel, Dwayne; Tansel, Ibrahim N.

    2018-01-01

    Array systems of transducers have found numerous applications in detection and localization of defects in structural health monitoring (SHM) of plate-like structures. Different types of array configurations and analysis algorithms have been used to improve the process of localization of defects. For accurate and reliable monitoring of large structures by array systems, a high number of actuator and sensor elements are often required. In this study, a compact phased array system consisting of only three piezoelectric elements is used in conjunction with an updated total focusing method (TFM) for localization of single and multiple defects in an aluminum plate. The accuracy of the localization process was greatly improved by including wave propagation information in TFM. Results indicated that the proposed CPA approach can locate single and multiple defects with high accuracy while decreasing the processing costs and the number of required transducers. This method can be utilized in critical applications such as aerospace structures where the use of a large number of transducers is not desirable.

  15. Method for facilitating the introduction of material into cells

    DOEpatents

    Holcomb, David E.; McKnight, Timothy E.

    2000-01-01

    The present invention is a method for creating a localized disruption within a boundary of a cell or structure by exposing a boundary of a cell or structure to a set of energetically charged particles while regulating the energy of the charged particles so that the charged particles have an amount of kinetic energy sufficient to create a localized disruption within an area of the boundary of the cell or structure, then upon creation of the localized disruption, the amount of kinetic energy decreases to an amount insufficient to create further damage within the cell or structure beyond the boundary. The present invention is also a method for facilitating the introduction of a material into a cell or structure using the same methodology then further exciting the area of the boundary of the cell or structure where the localized disruption was created so to create a localized temporary opening within the boundary then further introducing the material through the temporary opening into the cell or structure.

  16. Automated acoustic localization and call association for vocalizing humpback whales on the Navy's Pacific Missile Range Facility.

    PubMed

    Helble, Tyler A; Ierley, Glenn R; D'Spain, Gerald L; Martin, Stephen W

    2015-01-01

    Time difference of arrival (TDOA) methods for acoustically localizing multiple marine mammals have been applied to recorded data from the Navy's Pacific Missile Range Facility in order to localize and track humpback whales. Modifications to established methods were necessary in order to simultaneously track multiple animals on the range faster than real-time and in a fully automated way, while minimizing the number of incorrect localizations. The resulting algorithms were run with no human intervention at computational speeds faster than the data recording speed on over forty days of acoustic recordings from the range, spanning multiple years. Spatial localizations based on correlating sequences of units originating from within the range produce estimates having a standard deviation typically 10 m or less (due primarily to TDOA measurement errors), and a bias of 20 m or less (due primarily to sound speed mismatch). An automated method for associating units to individual whales is presented, enabling automated humpback song analyses to be performed.

  17. BUSCA: an integrative web server to predict subcellular localization of proteins.

    PubMed

    Savojardo, Castrense; Martelli, Pier Luigi; Fariselli, Piero; Profiti, Giuseppe; Casadio, Rita

    2018-04-30

    Here, we present BUSCA (http://busca.biocomp.unibo.it), a novel web server that integrates different computational tools for predicting protein subcellular localization. BUSCA combines methods for identifying signal and transit peptides (DeepSig and TPpred3), GPI-anchors (PredGPI) and transmembrane domains (ENSEMBLE3.0 and BetAware) with tools for discriminating subcellular localization of both globular and membrane proteins (BaCelLo, MemLoci and SChloro). Outcomes from the different tools are processed and integrated for annotating subcellular localization of both eukaryotic and bacterial protein sequences. We benchmark BUSCA against protein targets derived from recent CAFA experiments and other specific data sets, reporting performance at the state-of-the-art. BUSCA scores better than all other evaluated methods on 2732 targets from CAFA2, with a F1 value equal to 0.49 and among the best methods when predicting targets from CAFA3. We propose BUSCA as an integrated and accurate resource for the annotation of protein subcellular localization.

  18. APPLICATION OF ISOTOPE ENCEPHALOGRAPHY AND ELECTROENCEPHALOSCOPY FOR LOCALIZATION OF BRAIN TUMOURS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shamov, V.N.; Badmayev, C.N.; Bekhtereva, N.P.

    1959-10-31

    The problems of diagnosis and localization of brain tumors in some cases present many difficulities and make the neurosurgeon seek for additional methods of investigation. In such circumstances usage of the tracer technique in diagnostics is of considerable help, as it has obvious advantages compared with other methods of investigation, such as safety, painlessness, non-traumatism, absence of undesirable after effects, accuracy, and relative simplicity. The present communication is based on the results of clinical observations on 150 patients with verified brain tumors. Analyses of the data show that the accuracy of the brain tumor localizations vary, depending upon the depthmore » of the tumor site and conceniration of labelled material in the area of tumor growth. The diagnostic value of the method is doubtful in cases of tumors of posterior fossa, base of the brain, or the lesions of median line. The application of isotope encephalography is successfully supplemented by the new method of investigations, i.e., electroencephaloscopy, which allows the localization of deeply set tumors. Possibilities and limitations of the method are discussed. It is concluded that the isotope encephalography and electroencephaloscopy represent very valuable diagnostic methods which alongside with other auxiliary methods are widely used in diagnosis of brain tumors. (C.H.)« less

  19. Development and evaluation of a local grid refinement method for block-centered finite-difference groundwater models using shared nodes

    USGS Publications Warehouse

    Mehl, S.; Hill, M.C.

    2002-01-01

    A new method of local grid refinement for two-dimensional block-centered finite-difference meshes is presented in the context of steady-state groundwater-flow modeling. The method uses an iteration-based feedback with shared nodes to couple two separate grids. The new method is evaluated by comparison with results using a uniform fine mesh, a variably spaced mesh, and a traditional method of local grid refinement without a feedback. Results indicate: (1) The new method exhibits quadratic convergence for homogeneous systems and convergence equivalent to uniform-grid refinement for heterogeneous systems. (2) Coupling the coarse grid with the refined grid in a numerically rigorous way allowed for improvement in the coarse-grid results. (3) For heterogeneous systems, commonly used linear interpolation of heads from the large model onto the boundary of the refined model produced heads that are inconsistent with the physics of the flow field. (4) The traditional method works well in situations where the better resolution of the locally refined grid has little influence on the overall flow-system dynamics, but if this is not true, lack of a feedback mechanism produced errors in head up to 3.6% and errors in cell-to-cell flows up to 25%. ?? 2002 Elsevier Science Ltd. All rights reserved.

  20. Hippocampus Segmentation Based on Local Linear Mapping

    PubMed Central

    Pang, Shumao; Jiang, Jun; Lu, Zhentai; Li, Xueli; Yang, Wei; Huang, Meiyan; Zhang, Yu; Feng, Yanqiu; Huang, Wenhua; Feng, Qianjin

    2017-01-01

    We propose local linear mapping (LLM), a novel fusion framework for distance field (DF) to perform automatic hippocampus segmentation. A k-means cluster method is propose for constructing magnetic resonance (MR) and DF dictionaries. In LLM, we assume that the MR and DF samples are located on two nonlinear manifolds and the mapping from the MR manifold to the DF manifold is differentiable and locally linear. We combine the MR dictionary using local linear representation to present the test sample, and combine the DF dictionary using the corresponding coefficients derived from local linear representation procedure to predict the DF of the test sample. We then merge the overlapped predicted DF patch to obtain the DF value of each point in the test image via a confidence-based weighted average method. This approach enabled us to estimate the label of the test image according to the predicted DF. The proposed method was evaluated on brain images of 35 subjects obtained from SATA dataset. Results indicate the effectiveness of the proposed method, which yields mean Dice similarity coefficients of 0.8697, 0.8770 and 0.8734 for the left, right and bi-lateral hippocampus, respectively. PMID:28368016

  1. Hippocampus Segmentation Based on Local Linear Mapping.

    PubMed

    Pang, Shumao; Jiang, Jun; Lu, Zhentai; Li, Xueli; Yang, Wei; Huang, Meiyan; Zhang, Yu; Feng, Yanqiu; Huang, Wenhua; Feng, Qianjin

    2017-04-03

    We propose local linear mapping (LLM), a novel fusion framework for distance field (DF) to perform automatic hippocampus segmentation. A k-means cluster method is propose for constructing magnetic resonance (MR) and DF dictionaries. In LLM, we assume that the MR and DF samples are located on two nonlinear manifolds and the mapping from the MR manifold to the DF manifold is differentiable and locally linear. We combine the MR dictionary using local linear representation to present the test sample, and combine the DF dictionary using the corresponding coefficients derived from local linear representation procedure to predict the DF of the test sample. We then merge the overlapped predicted DF patch to obtain the DF value of each point in the test image via a confidence-based weighted average method. This approach enabled us to estimate the label of the test image according to the predicted DF. The proposed method was evaluated on brain images of 35 subjects obtained from SATA dataset. Results indicate the effectiveness of the proposed method, which yields mean Dice similarity coefficients of 0.8697, 0.8770 and 0.8734 for the left, right and bi-lateral hippocampus, respectively.

  2. Palm Vein Verification Using Multiple Features and Locality Preserving Projections

    PubMed Central

    Bu, Wei; Wu, Xiangqian; Zhao, Qiushi

    2014-01-01

    Biometrics is defined as identifying people by their physiological characteristic, such as iris pattern, fingerprint, and face, or by some aspects of their behavior, such as voice, signature, and gesture. Considerable attention has been drawn on these issues during the last several decades. And many biometric systems for commercial applications have been successfully developed. Recently, the vein pattern biometric becomes increasingly attractive for its uniqueness, stability, and noninvasiveness. A vein pattern is the physical distribution structure of the blood vessels underneath a person's skin. The palm vein pattern is very ganglion and it shows a huge number of vessels. The attitude of the palm vein vessels stays in the same location for the whole life and its pattern is definitely unique. In our work, the matching filter method is proposed for the palm vein image enhancement. New palm vein features extraction methods, global feature extracted based on wavelet coefficients and locality preserving projections (WLPP), and local feature based on local binary pattern variance and locality preserving projections (LBPV_LPP) have been proposed. Finally, the nearest neighbour matching method has been proposed that verified the test palm vein images. The experimental result shows that the EER to the proposed method is 0.1378%. PMID:24693230

  3. Impact of Tumor Localization and Method of Preoperative Biopsy on Sentinel Lymph Node Mapping After Periareolar Nuclide Injection.

    PubMed

    Krammer, Julia; Dutschke, Anja; Kaiser, Clemens G; Schnitzer, Andreas; Gerhardt, Axel; Radosa, Julia C; Brade, Joachim; Schoenberg, Stefan O; Wasser, Klaus

    2016-01-01

    To evaluate whether tumor localization and method of preoperative biopsy affect sentinel lymph node (SLN) detection after periareolar nuclide injection in breast cancer patients. 767 breast cancer patients were retrospectively included. For lymphscintigraphy periareolar nuclide injection was performed and the SLN was located by gamma camera. Patient and tumor characteristics were correlated to the success rate of SLN mapping. SLN marking failed in 9/61 (14.7%) patients with prior vacuum-assisted biopsy and 80/706 (11.3%) patients with prior core needle biopsy. Individually evaluated, biopsy method (p = 0.4) and tumor localization (p = 0.9) did not significantly affect the SLN detection rate. Patients with a vacuum-assisted biopsy of a tumor in the upper outer quadrant had a higher odds ratio of failing in SLN mapping (OR 3.8, p = 0.09) compared to core needle biopsy in the same localization (OR 0.9, p = 0.5). Tumor localization and preoperative biopsy method do not significantly impact SLN mapping with periareolar nuclide injection. However, the failure risk tends to rise if vacuum-assisted biopsy of a tumor in the upper outer quadrant is performed.

  4. Hippocampus Segmentation Based on Local Linear Mapping

    NASA Astrophysics Data System (ADS)

    Pang, Shumao; Jiang, Jun; Lu, Zhentai; Li, Xueli; Yang, Wei; Huang, Meiyan; Zhang, Yu; Feng, Yanqiu; Huang, Wenhua; Feng, Qianjin

    2017-04-01

    We propose local linear mapping (LLM), a novel fusion framework for distance field (DF) to perform automatic hippocampus segmentation. A k-means cluster method is propose for constructing magnetic resonance (MR) and DF dictionaries. In LLM, we assume that the MR and DF samples are located on two nonlinear manifolds and the mapping from the MR manifold to the DF manifold is differentiable and locally linear. We combine the MR dictionary using local linear representation to present the test sample, and combine the DF dictionary using the corresponding coefficients derived from local linear representation procedure to predict the DF of the test sample. We then merge the overlapped predicted DF patch to obtain the DF value of each point in the test image via a confidence-based weighted average method. This approach enabled us to estimate the label of the test image according to the predicted DF. The proposed method was evaluated on brain images of 35 subjects obtained from SATA dataset. Results indicate the effectiveness of the proposed method, which yields mean Dice similarity coefficients of 0.8697, 0.8770 and 0.8734 for the left, right and bi-lateral hippocampus, respectively.

  5. Palm vein verification using multiple features and locality preserving projections.

    PubMed

    Al-Juboori, Ali Mohsin; Bu, Wei; Wu, Xiangqian; Zhao, Qiushi

    2014-01-01

    Biometrics is defined as identifying people by their physiological characteristic, such as iris pattern, fingerprint, and face, or by some aspects of their behavior, such as voice, signature, and gesture. Considerable attention has been drawn on these issues during the last several decades. And many biometric systems for commercial applications have been successfully developed. Recently, the vein pattern biometric becomes increasingly attractive for its uniqueness, stability, and noninvasiveness. A vein pattern is the physical distribution structure of the blood vessels underneath a person's skin. The palm vein pattern is very ganglion and it shows a huge number of vessels. The attitude of the palm vein vessels stays in the same location for the whole life and its pattern is definitely unique. In our work, the matching filter method is proposed for the palm vein image enhancement. New palm vein features extraction methods, global feature extracted based on wavelet coefficients and locality preserving projections (WLPP), and local feature based on local binary pattern variance and locality preserving projections (LBPV_LPP) have been proposed. Finally, the nearest neighbour matching method has been proposed that verified the test palm vein images. The experimental result shows that the EER to the proposed method is 0.1378%.

  6. A new similarity index for nonlinear signal analysis based on local extrema patterns

    NASA Astrophysics Data System (ADS)

    Niknazar, Hamid; Motie Nasrabadi, Ali; Shamsollahi, Mohammad Bagher

    2018-02-01

    Common similarity measures of time domain signals such as cross-correlation and Symbolic Aggregate approximation (SAX) are not appropriate for nonlinear signal analysis. This is because of the high sensitivity of nonlinear systems to initial points. Therefore, a similarity measure for nonlinear signal analysis must be invariant to initial points and quantify the similarity by considering the main dynamics of signals. The statistical behavior of local extrema (SBLE) method was previously proposed to address this problem. The SBLE similarity index uses quantized amplitudes of local extrema to quantify the dynamical similarity of signals by considering patterns of sequential local extrema. By adding time information of local extrema as well as fuzzifying quantized values, this work proposes a new similarity index for nonlinear and long-term signal analysis, which extends the SBLE method. These new features provide more information about signals and reduce noise sensitivity by fuzzifying them. A number of practical tests were performed to demonstrate the ability of the method in nonlinear signal clustering and classification on synthetic data. In addition, epileptic seizure detection based on electroencephalography (EEG) signal processing was done by the proposed similarity to feature the potentials of the method as a real-world application tool.

  7. Facial expression recognition under partial occlusion based on fusion of global and local features

    NASA Astrophysics Data System (ADS)

    Wang, Xiaohua; Xia, Chen; Hu, Min; Ren, Fuji

    2018-04-01

    Facial expression recognition under partial occlusion is a challenging research. This paper proposes a novel framework for facial expression recognition under occlusion by fusing the global and local features. In global aspect, first, information entropy are employed to locate the occluded region. Second, principal Component Analysis (PCA) method is adopted to reconstruct the occlusion region of image. After that, a replace strategy is applied to reconstruct image by replacing the occluded region with the corresponding region of the best matched image in training set, Pyramid Weber Local Descriptor (PWLD) feature is then extracted. At last, the outputs of SVM are fitted to the probabilities of the target class by using sigmoid function. For the local aspect, an overlapping block-based method is adopted to extract WLD features, and each block is weighted adaptively by information entropy, Chi-square distance and similar block summation methods are then applied to obtain the probabilities which emotion belongs to. Finally, fusion at the decision level is employed for the data fusion of the global and local features based on Dempster-Shafer theory of evidence. Experimental results on the Cohn-Kanade and JAFFE databases demonstrate the effectiveness and fault tolerance of this method.

  8. Determining localized garment insulation values from manikin studies: computational method and results.

    PubMed

    Nelson, D A; Curlee, J S; Curran, A R; Ziriax, J M; Mason, P A

    2005-12-01

    The localized thermal insulation value expresses a garment's thermal resistance over the region which is covered by the garment, rather than over the entire surface of a subject or manikin. The determination of localized garment insulation values is critical to the development of high-resolution models of sensible heat exchange. A method is presented for determining and validating localized garment insulation values, based on whole-body insulation values (clo units) and using computer-aided design and thermal analysis software. Localized insulation values are presented for a catalog consisting of 106 garments and verified using computer-generated models. The values presented are suitable for use on volume element-based or surface element-based models of heat transfer involving clothed subjects.

  9. Comparison of estimation methods for creating small area rates of acute myocardial infarction among Medicare beneficiaries in California.

    PubMed

    Yasaitis, Laura C; Arcaya, Mariana C; Subramanian, S V

    2015-09-01

    Creating local population health measures from administrative data would be useful for health policy and public health monitoring purposes. While a wide range of options--from simple spatial smoothers to model-based methods--for estimating such rates exists, there are relatively few side-by-side comparisons, especially not with real-world data. In this paper, we compare methods for creating local estimates of acute myocardial infarction rates from Medicare claims data. A Bayesian Monte Carlo Markov Chain estimator that incorporated spatial and local random effects performed best, followed by a method-of-moments spatial Empirical Bayes estimator. As the former is more complicated and time-consuming, spatial linear Empirical Bayes methods may represent a good alternative for non-specialist investigators. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Detecting local haplotype sharing and haplotype association

    USDA-ARS?s Scientific Manuscript database

    A novel haplotype association method is presented, and its power is demonstrated. Relying on a statistical model for linkage disequilibrium (LD), the method first infers ancestral haplotypes and their loadings at each marker for each individual. The loadings are then used to quantify local haplotype...

  11. Numerical modeling of local scour around hydraulic structure in sandy beds by dynamic mesh method

    NASA Astrophysics Data System (ADS)

    Fan, Fei; Liang, Bingchen; Bai, Yuchuan; Zhu, Zhixia; Zhu, Yanjun

    2017-10-01

    Local scour, a non-negligible factor in hydraulic engineering, endangers the safety of hydraulic structures. In this work, a numerical model for simulating local scour was constructed, based on the open source code computational fluid dynamics model OpenFOAM. We consider both the bedload and suspended load sediment transport in the scour model and adopt the dynamic mesh method to simulate the evolution of the bed elevation. We use the finite area method to project data between the three-dimensional flow model and the two-dimensional (2D) scour model. We also improved the 2D sand slide method and added it to the scour model to correct the bed bathymetry when the bed slope angle exceeds the angle of repose. Moreover, to validate our scour model, we conducted and compared the results of three experiments with those of the developed model. The validation results show that our developed model can reliably simulate local scour.

  12. Calling depths of baleen whales from single sensor data: development of an autocorrelation method using multipath localization.

    PubMed

    Valtierra, Robert D; Glynn Holt, R; Cholewiak, Danielle; Van Parijs, Sofie M

    2013-09-01

    Multipath localization techniques have not previously been applied to baleen whale vocalizations due to difficulties in application to tonal vocalizations. Here it is shown that an autocorrelation method coupled with the direct reflected time difference of arrival localization technique can successfully resolve location information. A derivation was made to model the autocorrelation of a direct signal and its overlapping reflections to illustrate that an autocorrelation may be used to extract reflection information from longer duration signals containing a frequency sweep, such as some calls produced by baleen whales. An analysis was performed to characterize the difference in behavior of the autocorrelation when applied to call types with varying parameters (sweep rate, call duration). The method's feasibility was tested using data from playback transmissions to localize an acoustic transducer at a known depth and location. The method was then used to estimate the depth and range of a single North Atlantic right whale (Eubalaena glacialis) and humpback whale (Megaptera novaeangliae) from two separate experiments.

  13. Statistical lamb wave localization based on extreme value theory

    NASA Astrophysics Data System (ADS)

    Harley, Joel B.

    2018-04-01

    Guided wave localization methods based on delay-and-sum imaging, matched field processing, and other techniques have been designed and researched to create images that locate and describe structural damage. The maximum value of these images typically represent an estimated damage location. Yet, it is often unclear if this maximum value, or any other value in the image, is a statistically significant indicator of damage. Furthermore, there are currently few, if any, approaches to assess the statistical significance of guided wave localization images. As a result, we present statistical delay-and-sum and statistical matched field processing localization methods to create statistically significant images of damage. Our framework uses constant rate of false alarm statistics and extreme value theory to detect damage with little prior information. We demonstrate our methods with in situ guided wave data from an aluminum plate to detect two 0.75 cm diameter holes. Our results show an expected improvement in statistical significance as the number of sensors increase. With seventeen sensors, both methods successfully detect damage with statistical significance.

  14. Local region power spectrum-based unfocused ship detection method in synthetic aperture radar images

    NASA Astrophysics Data System (ADS)

    Wei, Xiangfei; Wang, Xiaoqing; Chong, Jinsong

    2018-01-01

    Ships on synthetic aperture radar (SAR) images will be severely defocused and their energy will disperse into numerous resolution cells under long SAR integration time. Therefore, the image intensity of ships is weak and sometimes even overwhelmed by sea clutter on SAR image. Consequently, it is hard to detect the ships from SAR intensity images. A ship detection method based on local region power spectrum of SAR complex image is proposed. Although the energies of the ships are dispersed on SAR intensity images, their spectral energies are rather concentrated or will cause the power spectra of local areas of SAR images to deviate from that of sea surface background. Therefore, the key idea of the proposed method is to detect ships via the power spectra distortion of local areas of SAR images. The local region power spectrum of a moving target on SAR image is analyzed and the way to obtain the detection threshold through the probability density function (pdf) of the power spectrum is illustrated. Numerical P- and L-band airborne SAR ocean data are utilized and the detection results are also illustrated. Results show that the proposed method can well detect the unfocused ships, with a detection rate of 93.6% and a false-alarm rate of 8.6%. Moreover, by comparing with some other algorithms, it indicates that the proposed method performs better under long SAR integration time. Finally, the applicability of the proposed method and the way of parameters selection are also discussed.

  15. Exact density functional and wave function embedding schemes based on orbital localization

    NASA Astrophysics Data System (ADS)

    Hégely, Bence; Nagy, Péter R.; Ferenczy, György G.; Kállay, Mihály

    2016-08-01

    Exact schemes for the embedding of density functional theory (DFT) and wave function theory (WFT) methods into lower-level DFT or WFT approaches are introduced utilizing orbital localization. First, a simple modification of the projector-based embedding scheme of Manby and co-workers [J. Chem. Phys. 140, 18A507 (2014)] is proposed. We also use localized orbitals to partition the system, but instead of augmenting the Fock operator with a somewhat arbitrary level-shift projector we solve the Huzinaga-equation, which strictly enforces the Pauli exclusion principle. Second, the embedding of WFT methods in local correlation approaches is studied. Since the latter methods split up the system into local domains, very simple embedding theories can be defined if the domains of the active subsystem and the environment are treated at a different level. The considered embedding schemes are benchmarked for reaction energies and compared to quantum mechanics (QM)/molecular mechanics (MM) and vacuum embedding. We conclude that for DFT-in-DFT embedding, the Huzinaga-equation-based scheme is more efficient than the other approaches, but QM/MM or even simple vacuum embedding is still competitive in particular cases. Concerning the embedding of wave function methods, the clear winner is the embedding of WFT into low-level local correlation approaches, and WFT-in-DFT embedding can only be more advantageous if a non-hybrid density functional is employed.

  16. Locally Linear Embedding of Local Orthogonal Least Squares Images for Face Recognition

    NASA Astrophysics Data System (ADS)

    Hafizhelmi Kamaru Zaman, Fadhlan

    2018-03-01

    Dimensionality reduction is very important in face recognition since it ensures that high-dimensionality data can be mapped to lower dimensional space without losing salient and integral facial information. Locally Linear Embedding (LLE) has been previously used to serve this purpose, however, the process of acquiring LLE features requires high computation and resources. To overcome this limitation, we propose a locally-applied Local Orthogonal Least Squares (LOLS) model can be used as initial feature extraction before the application of LLE. By construction of least squares regression under orthogonal constraints we can preserve more discriminant information in the local subspace of facial features while reducing the overall features into a more compact form that we called LOLS images. LLE can then be applied on the LOLS images to maps its representation into a global coordinate system of much lower dimensionality. Several experiments carried out using publicly available face datasets such as AR, ORL, YaleB, and FERET under Single Sample Per Person (SSPP) constraint demonstrates that our proposed method can reduce the time required to compute LLE features while delivering better accuracy when compared to when either LLE or OLS alone is used. Comparison against several other feature extraction methods and more recent feature-learning method such as state-of-the-art Convolutional Neural Networks (CNN) also reveal the superiority of the proposed method under SSPP constraint.

  17. Localizing New Pulsars with Intensity Mapping

    NASA Astrophysics Data System (ADS)

    Swiggum, Joe; Gentile, Peter

    2018-01-01

    Although low-frequency, single dish pulsar surveys provide an efficient means of searching large regions of sky quickly, the localization of new discoveries is poor. For example, discoveries from 350 MHz surveys using the Green Bank Telescope (GBT) have position uncertainties up to the FWHM of the telescope's "beam" on the sky, over half a degree! Before finding a coherent timing solution (requires 8-12 months of dedicated timing observations) a "gridding" method is usually employed to improve localization of new pulsars, whereby a grid of higher frequency beam positions is used to tile the initial error region. This method often requires over an hour of observing time to achieve arcminute-precision localization (provided the pulsar is detectable at higher frequencies).Here, we describe another method that uses the same observing frequency as the discovery observation and scans over Right Ascension and Declination directions around the nominal position. A Gaussian beam model is fit to folded pulse profile intensities as a function of time/position to provide improved localization. Using five test cases, we show that intensity mapping localization at 350 MHz with the GBT yields pulsar positions to 1 arcminute precision, facilitating high-frequency follow-up and higher significance detections for future pulsar timing. This method is also well suited to be directly implemented in future low-frequency drift scan pulsar surveys (e.g. with the Five hundred meter Aperture Spherical Telescope; FAST).

  18. Nonlocal and Mixed-Locality Multiscale Finite Element Methods

    DOE PAGES

    Costa, Timothy B.; Bond, Stephen D.; Littlewood, David J.

    2018-03-27

    In many applications the resolution of small-scale heterogeneities remains a significant hurdle to robust and reliable predictive simulations. In particular, while material variability at the mesoscale plays a fundamental role in processes such as material failure, the resolution required to capture mechanisms at this scale is often computationally intractable. Multiscale methods aim to overcome this difficulty through judicious choice of a subscale problem and a robust manner of passing information between scales. One promising approach is the multiscale finite element method, which increases the fidelity of macroscale simulations by solving lower-scale problems that produce enriched multiscale basis functions. Here, inmore » this study, we present the first work toward application of the multiscale finite element method to the nonlocal peridynamic theory of solid mechanics. This is achieved within the context of a discontinuous Galerkin framework that facilitates the description of material discontinuities and does not assume the existence of spatial derivatives. Analysis of the resulting nonlocal multiscale finite element method is achieved using the ambulant Galerkin method, developed here with sufficient generality to allow for application to multiscale finite element methods for both local and nonlocal models that satisfy minimal assumptions. Finally, we conclude with preliminary results on a mixed-locality multiscale finite element method in which a nonlocal model is applied at the fine scale and a local model at the coarse scale.« less

  19. Nonlocal and Mixed-Locality Multiscale Finite Element Methods

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Costa, Timothy B.; Bond, Stephen D.; Littlewood, David J.

    In many applications the resolution of small-scale heterogeneities remains a significant hurdle to robust and reliable predictive simulations. In particular, while material variability at the mesoscale plays a fundamental role in processes such as material failure, the resolution required to capture mechanisms at this scale is often computationally intractable. Multiscale methods aim to overcome this difficulty through judicious choice of a subscale problem and a robust manner of passing information between scales. One promising approach is the multiscale finite element method, which increases the fidelity of macroscale simulations by solving lower-scale problems that produce enriched multiscale basis functions. Here, inmore » this study, we present the first work toward application of the multiscale finite element method to the nonlocal peridynamic theory of solid mechanics. This is achieved within the context of a discontinuous Galerkin framework that facilitates the description of material discontinuities and does not assume the existence of spatial derivatives. Analysis of the resulting nonlocal multiscale finite element method is achieved using the ambulant Galerkin method, developed here with sufficient generality to allow for application to multiscale finite element methods for both local and nonlocal models that satisfy minimal assumptions. Finally, we conclude with preliminary results on a mixed-locality multiscale finite element method in which a nonlocal model is applied at the fine scale and a local model at the coarse scale.« less

  20. Single-molecule diffusion and conformational dynamics by spatial integration of temporal fluctuations

    PubMed Central

    Serag, Maged F.; Abadi, Maram; Habuchi, Satoshi

    2014-01-01

    Single-molecule localization and tracking has been used to translate spatiotemporal information of individual molecules to map their diffusion behaviours. However, accurate analysis of diffusion behaviours and including other parameters, such as the conformation and size of molecules, remain as limitations to the method. Here, we report a method that addresses the limitations of existing single-molecular localization methods. The method is based on temporal tracking of the cumulative area occupied by molecules. These temporal fluctuations are tied to molecular size, rates of diffusion and conformational changes. By analysing fluorescent nanospheres and double-stranded DNA molecules of different lengths and topological forms, we demonstrate that our cumulative-area method surpasses the conventional single-molecule localization method in terms of the accuracy of determined diffusion coefficients. Furthermore, the cumulative-area method provides conformational relaxation times of structurally flexible chains along with diffusion coefficients, which together are relevant to work in a wide spectrum of scientific fields. PMID:25283876

  1. The Robin Hood method - A novel numerical method for electrostatic problems based on a non-local charge transfer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lazic, Predrag; Stefancic, Hrvoje; Abraham, Hrvoje

    2006-03-20

    We introduce a novel numerical method, named the Robin Hood method, of solving electrostatic problems. The approach of the method is closest to the boundary element methods, although significant conceptual differences exist with respect to this class of methods. The method achieves equipotentiality of conducting surfaces by iterative non-local charge transfer. For each of the conducting surfaces, non-local charge transfers are performed between surface elements, which differ the most from the targeted equipotentiality of the surface. The method is tested against analytical solutions and its wide range of application is demonstrated. The method has appealing technical characteristics. For the problemmore » with N surface elements, the computational complexity of the method essentially scales with N {sup {alpha}}, where {alpha} < 2, the required computer memory scales with N, while the error of the potential decreases exponentially with the number of iterations for many orders of magnitude of the error, without the presence of the Critical Slowing Down. The Robin Hood method could prove useful in other classical or even quantum problems. Some future development ideas for possible applications outside electrostatics are addressed.« less

  2. Solutions to Kuessner's integral equation in unsteady flow using local basis functions

    NASA Technical Reports Server (NTRS)

    Fromme, J. A.; Halstead, D. W.

    1975-01-01

    The computational procedure and numerical results are presented for a new method to solve Kuessner's integral equation in the case of subsonic compressible flow about harmonically oscillating planar surfaces with controls. Kuessner's equation is a linear transformation from pressure to normalwash. The unknown pressure is expanded in terms of prescribed basis functions and the unknown basis function coefficients are determined in the usual manner by satisfying the given normalwash distribution either collocationally or in the complex least squares sense. The present method of solution differs from previous ones in that the basis functions are defined in a continuous fashion over a relatively small portion of the aerodynamic surface and are zero elsewhere. This method, termed the local basis function method, combines the smoothness and accuracy of distribution methods with the simplicity and versatility of panel methods. Predictions by the local basis function method for unsteady flow are shown to be in excellent agreement with other methods. Also, potential improvements to the present method and extensions to more general classes of solutions are discussed.

  3. Reconstruction of human brain spontaneous activity based on frequency-pattern analysis of magnetoencephalography data

    PubMed Central

    Llinás, Rodolfo R.; Ustinin, Mikhail N.; Rykunov, Stanislav D.; Boyko, Anna I.; Sychev, Vyacheslav V.; Walton, Kerry D.; Rabello, Guilherme M.; Garcia, John

    2015-01-01

    A new method for the analysis and localization of brain activity has been developed, based on multichannel magnetic field recordings, over minutes, superimposed on the MRI of the individual. Here, a high resolution Fourier Transform is obtained over the entire recording period, leading to a detailed multi-frequency spectrum. Further analysis implements a total decomposition of the frequency components into functionally invariant entities, each having an invariant field pattern localizable in recording space. The method, addressed as functional tomography, makes it possible to find the distribution of magnetic field sources in space. Here, the method is applied to the analysis of simulated data, to oscillating signals activating a physical current dipoles phantom, and to recordings of spontaneous brain activity in 10 healthy adults. In the analysis of simulated data, 61 dipoles are localized with 0.7 mm precision. Concerning the physical phantom the method is able to localize three simultaneously activated current dipoles with 1 mm precision. Spatial resolution 3 mm was attained when localizing spontaneous alpha rhythm activity in 10 healthy adults, where the alpha peak was specified for each subject individually. Co-registration of the functional tomograms with each subject's head MRI localized alpha range activity to the occipital and/or posterior parietal brain region. This is the first application of this new functional tomography to human brain activity. The method successfully provides an overall view of brain electrical activity, a detailed spectral description and, combined with MRI, the localization of sources in anatomical brain space. PMID:26528119

  4. Contrast-Enhanced Ultrasound Angiogenesis Imaging by Mutual Information Analysis for Prostate Cancer Localization.

    PubMed

    Schalk, Stefan G; Demi, Libertario; Bouhouch, Nabil; Kuenen, Maarten P J; Postema, Arnoud W; de la Rosette, Jean J M C H; Wijkstra, Hessel; Tjalkens, Tjalling J; Mischi, Massimo

    2017-03-01

    The role of angiogenesis in cancer growth has stimulated research aimed at noninvasive cancer detection by blood perfusion imaging. Recently, contrast ultrasound dispersion imaging was proposed as an alternative method for angiogenesis imaging. After the intravenous injection of an ultrasound-contrast-agent bolus, dispersion can be indirectly estimated from the local similarity between neighboring time-intensity curves (TICs) measured by ultrasound imaging. Up until now, only linear similarity measures have been investigated. Motivated by the promising results of this approach in prostate cancer (PCa), we developed a novel dispersion estimation method based on mutual information, thus including nonlinear similarity, to further improve its ability to localize PCa. First, a simulation study was performed to establish the theoretical link between dispersion and mutual information. Next, the method's ability to localize PCa was validated in vivo in 23 patients (58 datasets) referred for radical prostatectomy by comparison with histology. A monotonic relationship between dispersion and mutual information was demonstrated. The in vivo study resulted in a receiver operating characteristic (ROC) curve area equal to 0.77, which was superior (p = 0.21-0.24) to that obtained by linear similarity measures (0.74-0.75) and (p <; 0.05) to that by conventional perfusion parameters (≤0.70). Mutual information between neighboring time-intensity curves can be used to indirectly estimate contrast dispersion and can lead to more accurate PCa localization. An improved PCa localization method can possibly lead to better grading and staging of tumors, and support focal-treatment guidance. Moreover, future employment of the method in other types of angiogenic cancer can be considered.

  5. Solution of Thermoelectricity Problems Energy Method

    NASA Astrophysics Data System (ADS)

    Niyazbek, Muheyat; Nogaybaeva, M. O.; Talp, Kuenssaule; Kudaikulov, A. A.

    2018-06-01

    On the basis of the fundamental laws of conservation of energy in conjunction with local quadratic spline functions was developed a universal computing algorithm, a method and associated software, which allows to investigate the Thermophysical insulated rod, with limited length, influenced by local heat flow, heat transfer and temperature

  6. LCS-TA to identify similar fragments in RNA 3D structures.

    PubMed

    Wiedemann, Jakub; Zok, Tomasz; Milostan, Maciej; Szachniuk, Marta

    2017-10-23

    In modern structural bioinformatics, comparison of molecular structures aimed to identify and assess similarities and differences between them is one of the most commonly performed procedures. It gives the basis for evaluation of in silico predicted models. It constitutes the preliminary step in searching for structural motifs. In particular, it supports tracing the molecular evolution. Faced with an ever-increasing amount of available structural data, researchers need a range of methods enabling comparative analysis of the structures from either global or local perspective. Herein, we present a new, superposition-independent method which processes pairs of RNA 3D structures to identify their local similarities. The similarity is considered in the context of structure bending and bonds' rotation which are described by torsion angles. In the analyzed RNA structures, the method finds the longest continuous segments that show similar torsion within a user-defined threshold. The length of the segment is provided as local similarity measure. The method has been implemented as LCS-TA algorithm (Longest Continuous Segments in Torsion Angle space) and is incorporated into our MCQ4Structures application, freely available for download from http://www.cs.put.poznan.pl/tzok/mcq/ . The presented approach ties torsion-angle-based method of structure analysis with the idea of local similarity identification by handling continuous 3D structure segments. The first method, implemented in MCQ4Structures, has been successfully utilized in RNA-Puzzles initiative. The second one, originally applied in Euclidean space, is a component of LGA (Local-Global Alignment) algorithm commonly used in assessing protein models submitted to CASP. This unique combination of concepts implemented in LCS-TA provides a new perspective on structure quality assessment in local and quantitative aspect. A series of computational experiments show the first results of applying our method to comparison of RNA 3D models. LCS-TA can be used for identifying strengths and weaknesses in the prediction of RNA tertiary structures.

  7. Health promotion activities in annual reports of local governments: 'Health for All' targets as a tool for content analysis.

    PubMed

    Andersson, Camilla M; Bjärås, Gunilla E M; Tillgren, Per; Ostenson, Claes-Göran

    2003-09-01

    This article presents an instrument to study the annual reporting of health promotion activities in local governments within the three intervention municipalities of the Stockholm Diabetes Prevention Program (SDPP). The content of health promotion activities are described and the strengths, weaknesses and relevance of the method to health promotion discussed. A content analysis of local governmental reports from 1995-2000 in three Swedish municipalities. A matrix with WHO's 38 'Health for All' (HFA) targets from 1991 was used when coding the local health promotion activities. There are many public health initiatives within the local governmental structure even if they are not always addressed as health promotion. The main focuses in the local governmental reports were environmental issues, unemployment, social care and welfare. Local governmental reports were found to be a useful source of information that could provide knowledge about the priorities and organizational capacities for health promotion within local authorities. Additionally the HFA targets were an effective tool to identify and categorize systematically local health promotion activities in the annual reports of local governments. Identifying local health promotion initiatives by local authorities may ease the development of a health perspective and joint actions within the existing political and administrative structure. This paper provides a complementary method of attaining and structuring information about the local community for developments in health promotion.

  8. Partial discharge localization in power transformers based on the sequential quadratic programming-genetic algorithm adopting acoustic emission techniques

    NASA Astrophysics Data System (ADS)

    Liu, Hua-Long; Liu, Hua-Dong

    2014-10-01

    Partial discharge (PD) in power transformers is one of the prime reasons resulting in insulation degradation and power faults. Hence, it is of great importance to study the techniques of the detection and localization of PD in theory and practice. The detection and localization of PD employing acoustic emission (AE) techniques, as a kind of non-destructive testing, plus due to the advantages of powerful capability of locating and high precision, have been paid more and more attention. The localization algorithm is the key factor to decide the localization accuracy in AE localization of PD. Many kinds of localization algorithms exist for the PD source localization adopting AE techniques including intelligent and non-intelligent algorithms. However, the existed algorithms possess some defects such as the premature convergence phenomenon, poor local optimization ability and unsuitability for the field applications. To overcome the poor local optimization ability and easily caused premature convergence phenomenon of the fundamental genetic algorithm (GA), a new kind of improved GA is proposed, namely the sequence quadratic programming-genetic algorithm (SQP-GA). For the hybrid optimization algorithm, SQP-GA, the sequence quadratic programming (SQP) algorithm which is used as a basic operator is integrated into the fundamental GA, so the local searching ability of the fundamental GA is improved effectively and the premature convergence phenomenon is overcome. Experimental results of the numerical simulations of benchmark functions show that the hybrid optimization algorithm, SQP-GA, is better than the fundamental GA in the convergence speed and optimization precision, and the proposed algorithm in this paper has outstanding optimization effect. At the same time, the presented SQP-GA in the paper is applied to solve the ultrasonic localization problem of PD in transformers, then the ultrasonic localization method of PD in transformers based on the SQP-GA is proposed. And localization results based on the SQP-GA are compared with some algorithms such as the GA, some other intelligent and non-intelligent algorithms. The results of calculating examples both stimulated and spot experiments demonstrate that the localization method based on the SQP-GA can effectively prevent the results from getting trapped into the local optimum values, and the localization method is of great feasibility and very suitable for the field applications, and the precision of localization is enhanced, and the effectiveness of localization is ideal and satisfactory.

  9. A special purpose knowledge-based face localization method

    NASA Astrophysics Data System (ADS)

    Hassanat, Ahmad; Jassim, Sabah

    2008-04-01

    This paper is concerned with face localization for visual speech recognition (VSR) system. Face detection and localization have got a great deal of attention in the last few years, because it is an essential pre-processing step in many techniques that handle or deal with faces, (e.g. age, face, gender, race and visual speech recognition). We shall present an efficient method for localization human's faces in video images captured on mobile constrained devices, under a wide variation in lighting conditions. We use a multiphase method that may include all or some of the following steps starting with image pre-processing, followed by a special purpose edge detection, then an image refinement step. The output image will be passed through a discrete wavelet decomposition procedure, and the computed LL sub-band at a certain level will be transformed into a binary image that will be scanned by using a special template to select a number of possible candidate locations. Finally, we fuse the scores from the wavelet step with scores determined by color information for the candidate location and employ a form of fuzzy logic to distinguish face from non-face locations. We shall present results of large number of experiments to demonstrate that the proposed face localization method is efficient and achieve high level of accuracy that outperforms existing general-purpose face detection methods.

  10. Estimating local noise power spectrum from a few FBP-reconstructed CT scans

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zeng, Rongping, E-mail: rongping.zeng@fda.hhs.gov; Gavrielides, Marios A.; Petrick, Nicholas

    Purpose: Traditional ways to estimate 2D CT noise power spectrum (NPS) involve an ensemble average of the power spectrums of many noisy scans. When only a few scans are available, regions of interest are often extracted from different locations to obtain sufficient samples to estimate the NPS. Using image samples from different locations ignores the nonstationarity of CT noise and thus cannot accurately characterize its local properties. The purpose of this work is to develop a method to estimate local NPS using only a few fan-beam CT scans. Methods: As a result of FBP reconstruction, the CT NPS has themore » same radial profile shape for all projection angles, with the magnitude varying with the noise level in the raw data measurement. This allows a 2D CT NPS to be factored into products of a 1D angular and a 1D radial function in polar coordinates. The polar separability of CT NPS greatly reduces the data requirement for estimating the NPS. The authors use this property and derive a radial NPS estimation method: in brief, the radial profile shape is estimated from a traditional NPS based on image samples extracted at multiple locations. The amplitudes are estimated by fitting the traditional local NPS to the estimated radial profile shape. The estimated radial profile shape and amplitudes are then combined to form a final estimate of the local NPS. We evaluate the accuracy of the radial NPS method and compared it to traditional NPS methods in terms of normalized mean squared error (NMSE) and signal detectability index. Results: For both simulated and real CT data sets, the local NPS estimated with no more than six scans using the radial NPS method was very close to the reference NPS, according to the metrics of NMSE and detectability index. Even with only two scans, the radial NPS method was able to achieve a fairly good accuracy. Compared to those estimated using traditional NPS methods, the accuracy improvement was substantial when a few scans were available. Conclusions: The radial NPS method was shown to be accurate and efficient in estimating the local NPS of FBP-reconstructed 2D CT images. It presents strong advantages over traditional NPS methods when the number of scans is limited and can be extended to estimate the in-plane NPS of cone-beam CT and multislice helical CT scans.« less

  11. Streamflow Prediction based on Chaos Theory

    NASA Astrophysics Data System (ADS)

    Li, X.; Wang, X.; Babovic, V. M.

    2015-12-01

    Chaos theory is a popular method in hydrologic time series prediction. Local model (LM) based on this theory utilizes time-delay embedding to reconstruct the phase-space diagram. For this method, its efficacy is dependent on the embedding parameters, i.e. embedding dimension, time lag, and nearest neighbor number. The optimal estimation of these parameters is thus critical to the application of Local model. However, these embedding parameters are conventionally estimated using Average Mutual Information (AMI) and False Nearest Neighbors (FNN) separately. This may leads to local optimization and thus has limitation to its prediction accuracy. Considering about these limitation, this paper applies a local model combined with simulated annealing (SA) to find the global optimization of embedding parameters. It is also compared with another global optimization approach of Genetic Algorithm (GA). These proposed hybrid methods are applied in daily and monthly streamflow time series for examination. The results show that global optimization can contribute to the local model to provide more accurate prediction results compared with local optimization. The LM combined with SA shows more advantages in terms of its computational efficiency. The proposed scheme here can also be applied to other fields such as prediction of hydro-climatic time series, error correction, etc.

  12. Local-metrics error-based Shepard interpolation as surrogate for highly non-linear material models in high dimensions

    NASA Astrophysics Data System (ADS)

    Lorenzi, Juan M.; Stecher, Thomas; Reuter, Karsten; Matera, Sebastian

    2017-10-01

    Many problems in computational materials science and chemistry require the evaluation of expensive functions with locally rapid changes, such as the turn-over frequency of first principles kinetic Monte Carlo models for heterogeneous catalysis. Because of the high computational cost, it is often desirable to replace the original with a surrogate model, e.g., for use in coupled multiscale simulations. The construction of surrogates becomes particularly challenging in high-dimensions. Here, we present a novel version of the modified Shepard interpolation method which can overcome the curse of dimensionality for such functions to give faithful reconstructions even from very modest numbers of function evaluations. The introduction of local metrics allows us to take advantage of the fact that, on a local scale, rapid variation often occurs only across a small number of directions. Furthermore, we use local error estimates to weigh different local approximations, which helps avoid artificial oscillations. Finally, we test our approach on a number of challenging analytic functions as well as a realistic kinetic Monte Carlo model. Our method not only outperforms existing isotropic metric Shepard methods but also state-of-the-art Gaussian process regression.

  13. Local-metrics error-based Shepard interpolation as surrogate for highly non-linear material models in high dimensions.

    PubMed

    Lorenzi, Juan M; Stecher, Thomas; Reuter, Karsten; Matera, Sebastian

    2017-10-28

    Many problems in computational materials science and chemistry require the evaluation of expensive functions with locally rapid changes, such as the turn-over frequency of first principles kinetic Monte Carlo models for heterogeneous catalysis. Because of the high computational cost, it is often desirable to replace the original with a surrogate model, e.g., for use in coupled multiscale simulations. The construction of surrogates becomes particularly challenging in high-dimensions. Here, we present a novel version of the modified Shepard interpolation method which can overcome the curse of dimensionality for such functions to give faithful reconstructions even from very modest numbers of function evaluations. The introduction of local metrics allows us to take advantage of the fact that, on a local scale, rapid variation often occurs only across a small number of directions. Furthermore, we use local error estimates to weigh different local approximations, which helps avoid artificial oscillations. Finally, we test our approach on a number of challenging analytic functions as well as a realistic kinetic Monte Carlo model. Our method not only outperforms existing isotropic metric Shepard methods but also state-of-the-art Gaussian process regression.

  14. A novel method for the extraction of local gravity wave parameters from gridded three-dimensional data: description, validation, and application

    NASA Astrophysics Data System (ADS)

    Schoon, Lena; Zülicke, Christoph

    2018-05-01

    For the local diagnosis of wave properties, we develop, validate, and apply a novel method which is based on the Hilbert transform. It is called Unified Wave Diagnostics (UWaDi). It provides the wave amplitude and three-dimensional wave number at any grid point for gridded three-dimensional data. UWaDi is validated for a synthetic test case comprising two different wave packets. In comparison with other methods, the performance of UWaDi is very good with respect to wave properties and their location. For a first practical application of UWaDi, a minor sudden stratospheric warming on 30 January 2016 is chosen. Specifying the diagnostics for hydrostatic inertia-gravity waves in analyses from the European Centre for Medium-Range Weather Forecasts, we detect the local occurrence of gravity waves throughout the middle atmosphere. The local wave characteristics are discussed in terms of vertical propagation using the diagnosed local amplitudes and wave numbers. We also note some hints on local inertia-gravity wave generation by the stratospheric jet from the detection of shallow slow waves in the vicinity of its exit region.

  15. Local durian (Durio zibethinus murr.) exploration for potentially superior tree as parents in Ngrambe District, Ngawi

    NASA Astrophysics Data System (ADS)

    Yuniastuti, E.; Anggita, A.; Nandariyah; Sukaya

    2018-03-01

    The characteristics durian based on specific area gives a wide diversity of phenotype. This research objective was to build an inventory of the local durian of Ngrambe as well as to obtain potentially superior local durian as prospective parent trees. The research was conducted in Ngrambe sub-district, on October 2015 until April 2016 using the explorative descriptive method. The determination of sample point used the non-probability method of snowball sampling type. Primary data include the morphology of plant characters, trunks, leaves, flower, fruits and seeds and their superiority. The data of the research were analyzed using SIMQUAL (Similarity for Qualitative) function based on the DICE coefficient on NTSYS v.2.02. The data cluster and dendrogram analyses were determined by Unweighted Pair-Group Arithmetic Average (UPGMA) method. The result of DICE coefficient analyses of 58 local durian accession based on the phenotypic character of vegetative organs ranged from 0.84-1.0. The phenotypic character of the vegetative and generative organ from 3 local durian accession superior potential ranged from 0.7 to 0.8. In conclusion, the accession of local durian which were Miyem and Rusmiyati have advantage and potential as prospective parent trees.

  16. Adjustment of interaural time difference in head related transfer functions based on listeners' anthropometry and its effect on sound localization

    NASA Astrophysics Data System (ADS)

    Suzuki, Yôiti; Watanabe, Kanji; Iwaya, Yukio; Gyoba, Jiro; Takane, Shouichi

    2005-04-01

    Because the transfer functions governing subjective sound localization (HRTFs) show strong individuality, sound localization systems based on synthesis of HRTFs require suitable HRTFs for individual listeners. However, it is impractical to obtain HRTFs for all listeners based on measurements. Improving sound localization by adjusting non-individualized HRTFs to a specific listener based on that listener's anthropometry might be a practical method. This study first developed a new method to estimate interaural time differences (ITDs) using HRTFs. Then correlations between ITDs and anthropometric parameters were analyzed using the canonical correlation method. Results indicated that parameters relating to head size, and shoulder and ear positions are significant. Consequently, it was attempted to express ITDs based on listener's anthropometric data. In this process, the change of ITDs as a function of azimuth angle was parameterized as a sum of sine functions. Then the parameters were analyzed using multiple regression analysis, in which the anthropometric parameters were used as explanatory variables. The predicted or individualized ITDs were installed in the nonindividualized HRTFs to evaluate sound localization performance. Results showed that individualization of ITDs improved horizontal sound localization.

  17. Prediction of CT Substitutes from MR Images Based on Local Diffeomorphic Mapping for Brain PET Attenuation Correction.

    PubMed

    Wu, Yao; Yang, Wei; Lu, Lijun; Lu, Zhentai; Zhong, Liming; Huang, Meiyan; Feng, Yanqiu; Feng, Qianjin; Chen, Wufan

    2016-10-01

    Attenuation correction is important for PET reconstruction. In PET/MR, MR intensities are not directly related to attenuation coefficients that are needed in PET imaging. The attenuation coefficient map can be derived from CT images. Therefore, prediction of CT substitutes from MR images is desired for attenuation correction in PET/MR. This study presents a patch-based method for CT prediction from MR images, generating attenuation maps for PET reconstruction. Because no global relation exists between MR and CT intensities, we propose local diffeomorphic mapping (LDM) for CT prediction. In LDM, we assume that MR and CT patches are located on 2 nonlinear manifolds, and the mapping from the MR manifold to the CT manifold approximates a diffeomorphism under a local constraint. Locality is important in LDM and is constrained by the following techniques. The first is local dictionary construction, wherein, for each patch in the testing MR image, a local search window is used to extract patches from training MR/CT pairs to construct MR and CT dictionaries. The k-nearest neighbors and an outlier detection strategy are then used to constrain the locality in MR and CT dictionaries. Second is local linear representation, wherein, local anchor embedding is used to solve MR dictionary coefficients when representing the MR testing sample. Under these local constraints, dictionary coefficients are linearly transferred from the MR manifold to the CT manifold and used to combine CT training samples to generate CT predictions. Our dataset contains 13 healthy subjects, each with T1- and T2-weighted MR and CT brain images. This method provides CT predictions with a mean absolute error of 110.1 Hounsfield units, Pearson linear correlation of 0.82, peak signal-to-noise ratio of 24.81 dB, and Dice in bone regions of 0.84 as compared with real CTs. CT substitute-based PET reconstruction has a regression slope of 1.0084 and R 2 of 0.9903 compared with real CT-based PET. In this method, no image segmentation or accurate registration is required. Our method demonstrates superior performance in CT prediction and PET reconstruction compared with competing methods. © 2016 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

  18. Initial conditions and degrees of freedom of non-local gravity

    NASA Astrophysics Data System (ADS)

    Calcagni, Gianluca; Modesto, Leonardo; Nardelli, Giuseppe

    2018-05-01

    We prove the equivalence between non-local gravity with an arbitrary form factor and a non-local gravitational system with an extra rank-2 symmetric tensor. Thanks to this reformulation, we use the diffusion-equation method to transform the dynamics of renormalizable non-local gravity with exponential operators into a higher-dimensional system local in spacetime coordinates. This method, first illustrated with a scalar field theory and then applied to gravity, allows one to solve the Cauchy problem and count the number of initial conditions and of non-perturbative degrees of freedom, which is finite. In particular, the non-local scalar and gravitational theories with exponential operators are both characterized by four initial conditions in any dimension and, respectively, by one and eight degrees of freedom in four dimensions. The fully covariant equations of motion are written in a form convenient to find analytic non-perturbative solutions.

  19. Unsupervised Indoor Localization Based on Smartphone Sensors, iBeacon and Wi-Fi.

    PubMed

    Chen, Jing; Zhang, Yi; Xue, Wei

    2018-04-28

    In this paper, we propose UILoc, an unsupervised indoor localization scheme that uses a combination of smartphone sensors, iBeacons and Wi-Fi fingerprints for reliable and accurate indoor localization with zero labor cost. Firstly, compared with the fingerprint-based method, the UILoc system can build a fingerprint database automatically without any site survey and the database will be applied in the fingerprint localization algorithm. Secondly, since the initial position is vital to the system, UILoc will provide the basic location estimation through the pedestrian dead reckoning (PDR) method. To provide accurate initial localization, this paper proposes an initial localization module, a weighted fusion algorithm combined with a k-nearest neighbors (KNN) algorithm and a least squares algorithm. In UILoc, we have also designed a reliable model to reduce the landmark correction error. Experimental results show that the UILoc can provide accurate positioning, the average localization error is about 1.1 m in the steady state, and the maximum error is 2.77 m.

  20. Talker Localization Based on Interference between Transmitted and Reflected Audible Sound

    NASA Astrophysics Data System (ADS)

    Nakayama, Masato; Nakasako, Noboru; Shinohara, Toshihiro; Uebo, Tetsuji

    In many engineering fields, distance to targets is very important. General distance measurement method uses a time delay between transmitted and reflected waves, but it is difficult to estimate the short distance. On the other hand, the method using phase interference to measure the short distance has been known in the field of microwave radar. Therefore, we have proposed the distance estimation method based on interference between transmitted and reflected audible sound, which can measure the distance between microphone and target with one microphone and one loudspeaker. In this paper, we propose talker localization method based on distance estimation using phase interference. We expand the distance estimation method using phase interference into two microphones (microphone array) in order to estimate talker position. The proposed method can estimate talker position by measuring the distance and direction between target and microphone array. In addition, talker's speech is regarded as a noise in the proposed method. Therefore, we also propose combination of the proposed method and CSP (Cross-power Spectrum Phase analysis) method which is one of the DOA (Direction Of Arrival) estimation methods. We evaluated the performance of talker localization in real environments. The experimental result shows the effectiveness of the proposed method.

  1. Cross-Cultural Adaptation of the Male Genital Self-Image Scale in Iranian Men.

    PubMed

    Saffari, Mohsen; Pakpour, Amir H; Burri, Andrea

    2016-03-01

    Certain sexual health problems in men can be attributed to genital self-image. Therefore, a culturally adapted version of a Male Genital Self-Image Scale (MGSIS) could help health professionals understand this concept and its associated correlates. To translate the original English version of the MGSIS into Persian and to assess the psychometric properties of this culturally adapted version (MGSIS-I) for use in Iranian men. In total, 1,784 men were recruited for this cross-sectional study. Backward and forward translations of the MGSIS were used to produce the culturally adapted version. Reliability of the MGSIS-I was assessed using Cronbach α and intra-class correlation coefficients. Divergent and convergent validities were examined using Pearson correlation and known-group validity was assessed in subgroups of participants with different sociodemographic statuses. Factor validity of the scale was investigated using exploratory and confirmatory factor analyses. Demographic information, the International Index of Erectile Function, the Body Appreciation Scale, the Rosenberg Self-Esteem Scale, and the MGSIS. Mean age of participants was 38.13 years (SD = 11.45) and all men were married. Cronbach α of the MGSIS-I was 0.89 and interclass correlation coefficients ranged from 0.70 to 0.94. Significant correlations were found between the MGSIS-I and the International Index of Erectile Function (P < .01), whereas correlation of the scale with non-similar scales was lower than with similar scale (confirming convergent and divergent validity). The scale could differentiate between subgroups in age, smoking status, and income (known-group validity). A single-factor solution that explained 70% variance of the scale was explored using exploratory factor analysis (confirming uni-dimensionality); confirmatory factor analysis indicated better fitness for the five-item version than the seven-item version of the MGSIS-I (root mean square error of approximation = 0.05, comparative fit index > 1.00 vs root mean square error of approximation = 0.10, comparative fit index > 0.97, respectively). The MGSIS-I is a useful instrument to assess genital self-image in Iranian men, a concept that has been associated with sexual function. Further investigation is needed to identify the applicability of the scale in other cultures or populations. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  2. Experimental investigation of a general real-time 3D target localization method using sequential kV imaging combined with respiratory monitoring.

    PubMed

    Cho, Byungchul; Poulsen, Per; Ruan, Dan; Sawant, Amit; Keall, Paul J

    2012-11-21

    The goal of this work was to experimentally quantify the geometric accuracy of a novel real-time 3D target localization method using sequential kV imaging combined with respiratory monitoring for clinically realistic arc and static field treatment delivery and target motion conditions. A general method for real-time target localization using kV imaging and respiratory monitoring was developed. Each dimension of internal target motion T(x, y, z; t) was estimated from the external respiratory signal R(t) through the correlation between R(t(i)) and the projected marker positions p(x(p), y(p); t(i)) on kV images by a state-augmented linear model: T(x, y, z; t) = aR(t) + bR(t - τ) + c. The model parameters, a, b, c, were determined by minimizing the squared fitting error ∑‖p(x(p), y(p); t(i)) - P(θ(i)) · (aR(t(i)) + bR(t(i) - τ) + c)‖(2) with the projection operator P(θ(i)). The model parameters were first initialized based on acquired kV arc images prior to MV beam delivery. This method was implemented on a trilogy linear accelerator consisting of an OBI x-ray imager (operating at 1 Hz) and real-time position monitoring (RPM) system (30 Hz). Arc and static field plans were delivered to a moving phantom programmed with measured lung tumour motion from ten patients. During delivery, the localization method determined the target position and the beam was adjusted in real time via dynamic multileaf collimator (DMLC) adaptation. The beam-target alignment error was quantified by segmenting the beam aperture and a phantom-embedded fiducial marker on MV images and analysing their relative position. With the localization method, the root-mean-squared errors of the ten lung tumour traces ranged from 0.7-1.3 mm and 0.8-1.4 mm during the single arc and five-field static beam delivery, respectively. Without the localization method, these errors ranged from 3.1-7.3 mm. In summary, a general method for real-time target localization using kV imaging and respiratory monitoring has been experimentally investigated for arc and static field delivery. The average beam-target error was 1 mm.

  3. Experimental investigation of a general real-time 3D target localization method using sequential kV imaging combined with respiratory monitoring

    NASA Astrophysics Data System (ADS)

    Cho, Byungchul; Poulsen, Per; Ruan, Dan; Sawant, Amit; Keall, Paul J.

    2012-11-01

    The goal of this work was to experimentally quantify the geometric accuracy of a novel real-time 3D target localization method using sequential kV imaging combined with respiratory monitoring for clinically realistic arc and static field treatment delivery and target motion conditions. A general method for real-time target localization using kV imaging and respiratory monitoring was developed. Each dimension of internal target motion T(x, y, z; t) was estimated from the external respiratory signal R(t) through the correlation between R(ti) and the projected marker positions p(xp, yp; ti) on kV images by a state-augmented linear model: T(x, y, z; t) = aR(t) + bR(t - τ) + c. The model parameters, a, b, c, were determined by minimizing the squared fitting error ∑‖p(xp, yp; ti) - P(θi) · (aR(ti) + bR(ti - τ) + c)‖2 with the projection operator P(θi). The model parameters were first initialized based on acquired kV arc images prior to MV beam delivery. This method was implemented on a trilogy linear accelerator consisting of an OBI x-ray imager (operating at 1 Hz) and real-time position monitoring (RPM) system (30 Hz). Arc and static field plans were delivered to a moving phantom programmed with measured lung tumour motion from ten patients. During delivery, the localization method determined the target position and the beam was adjusted in real time via dynamic multileaf collimator (DMLC) adaptation. The beam-target alignment error was quantified by segmenting the beam aperture and a phantom-embedded fiducial marker on MV images and analysing their relative position. With the localization method, the root-mean-squared errors of the ten lung tumour traces ranged from 0.7-1.3 mm and 0.8-1.4 mm during the single arc and five-field static beam delivery, respectively. Without the localization method, these errors ranged from 3.1-7.3 mm. In summary, a general method for real-time target localization using kV imaging and respiratory monitoring has been experimentally investigated for arc and static field delivery. The average beam-target error was 1 mm.

  4. Local bias-induced phase transitions

    DOE PAGES

    Seal, Katyayani; Baddorf, Arthur P.; Jesse, Stephen; ...

    2008-11-27

    Electrical bias-induced phase transitions underpin a wide range of applications from data storage to energy generation and conversion. The mechanisms behind these transitions are often quite complex and in many cases are extremely sensitive to local defects that act as centers for local transformations or pinning. Furthermore, using ferroelectrics as an example, we review methods for probing bias-induced phase transitions and discuss the current limitations and challenges for extending the methods to field-induced phase transitions and electrochemical reactions in energy storage, biological and molecular systems.

  5. Photometry unlocks 3D information from 2D localization microscopy data.

    PubMed

    Franke, Christian; Sauer, Markus; van de Linde, Sebastian

    2017-01-01

    We developed a straightforward photometric method, temporal, radial-aperture-based intensity estimation (TRABI), that allows users to extract 3D information from existing 2D localization microscopy data. TRABI uses the accurate determination of photon numbers in different regions of the emission pattern of single emitters to generate a z-dependent photometric parameter. This method can determine fluorophore positions up to 600 nm from the focal plane and can be combined with biplane detection to further improve axial localization.

  6. Qualitative Epidemiologic Methods Can Improve Local Prevention Programming among Adolescents

    ERIC Educational Resources Information Center

    Daniulaityte, Raminta; Siegal, Harvey A.; Carlson, Robert G.; Kenne, Deric R.; Starr, Sanford; DeCamp, Brad

    2004-01-01

    The Ohio Substance Abuse Monitoring Network (OSAM) is designed to provide accurate, timely, qualitatively-oriented epidemiologic descriptions of substance abuse trends and emerging problems in the state's major urban and rural areas. Use of qualitative methods in identifying and assessing substance abuse practices in local communities is one of…

  7. ABSCISSA ASSESSMENT WITH ALGAE: A COMPARISON OF LOCAL AND LANDSCAPE IMPAIRMENT MEASURES FOR BIOLOGICAL ASSESSMENT USING BENTHIC DIATOMS

    EPA Science Inventory

    The development of rigorous biological assessments is dependent upon well-constructed abscissa, and various methods, both subjective and objective, exist to measure expected impairment at both the landscape and local scale. A new, landscape-scale method has recently been offered...

  8. Measuring walking and cycling using the PABS (pedestrian and bicycling survey) approach : a low-cost survey method for local communities [research brief].

    DOT National Transportation Integrated Search

    2010-10-01

    Many communities want to promote walking and cycling. However, few know how much nonmotorized travel already occurs in their communities. This research project developed the Pedestrian and Bicycling Survey (PABS), a method that local governments can ...

  9. High-order local maximum principle preserving (MPP) discontinuous Galerkin finite element method for the transport equation

    NASA Astrophysics Data System (ADS)

    Anderson, R.; Dobrev, V.; Kolev, Tz.; Kuzmin, D.; Quezada de Luna, M.; Rieben, R.; Tomov, V.

    2017-04-01

    In this work we present a FCT-like Maximum-Principle Preserving (MPP) method to solve the transport equation. We use high-order polynomial spaces; in particular, we consider up to 5th order spaces in two and three dimensions and 23rd order spaces in one dimension. The method combines the concepts of positive basis functions for discontinuous Galerkin finite element spatial discretization, locally defined solution bounds, element-based flux correction, and non-linear local mass redistribution. We consider a simple 1D problem with non-smooth initial data to explain and understand the behavior of different parts of the method. Convergence tests in space indicate that high-order accuracy is achieved. Numerical results from several benchmarks in two and three dimensions are also reported.

  10. Local unitary transformation method for large-scale two-component relativistic calculations: case for a one-electron Dirac Hamiltonian.

    PubMed

    Seino, Junji; Nakai, Hiromi

    2012-06-28

    An accurate and efficient scheme for two-component relativistic calculations at the spin-free infinite-order Douglas-Kroll-Hess (IODKH) level is presented. The present scheme, termed local unitary transformation (LUT), is based on the locality of the relativistic effect. Numerical assessments of the LUT scheme were performed in diatomic molecules such as HX and X(2) (X = F, Cl, Br, I, and At) and hydrogen halide clusters, (HX)(n) (X = F, Cl, Br, and I). Total energies obtained by the LUT method agree well with conventional IODKH results. The computational costs of the LUT method are drastically lower than those of conventional methods since in the former there is linear-scaling with respect to the system size and a small prefactor.

  11. Solution of free-boundary problems using finite-element/Newton methods and locally refined grids - Application to analysis of solidification microstructure

    NASA Technical Reports Server (NTRS)

    Tsiveriotis, K.; Brown, R. A.

    1993-01-01

    A new method is presented for the solution of free-boundary problems using Lagrangian finite element approximations defined on locally refined grids. The formulation allows for direct transition from coarse to fine grids without introducing non-conforming basis functions. The calculation of elemental stiffness matrices and residual vectors are unaffected by changes in the refinement level, which are accounted for in the loading of elemental data to the global stiffness matrix and residual vector. This technique for local mesh refinement is combined with recently developed mapping methods and Newton's method to form an efficient algorithm for the solution of free-boundary problems, as demonstrated here by sample calculations of cellular interfacial microstructure during directional solidification of a binary alloy.

  12. A Multilevel Testlet Model for Dual Local Dependence

    ERIC Educational Resources Information Center

    Jiao, Hong; Kamata, Akihito; Wang, Shudong; Jin, Ying

    2012-01-01

    The applications of item response theory (IRT) models assume local item independence and that examinees are independent of each other. When a representative sample for psychometric analysis is selected using a cluster sampling method in a testlet-based assessment, both local item dependence and local person dependence are likely to be induced.…

  13. Targeted polypeptide degradation

    DOEpatents

    Church, George M [Brookline, MA; Janse, Daniel M [Brookline, MA

    2008-05-13

    This invention pertains to compositions, methods, cells and organisms useful for selectively localizing polypeptides to the proteasome for degradation. Therapeutic methods and pharmaceutical compositions for treating disorders associated with the expression and/or activity of a polypeptide by targeting these polypeptides for degradation, as well as methods for targeting therapeutic polypeptides for degradation and/or activating therapeutic polypeptides by degradation are provided. The invention provides methods for identifying compounds that mediate proteasome localization and/or polypeptide degradation. The invention also provides research tools for the study of protein function.

  14. Functional imaging with low-resolution brain electromagnetic tomography (LORETA): a review.

    PubMed

    Pascual-Marqui, R D; Esslen, M; Kochi, K; Lehmann, D

    2002-01-01

    This paper reviews several recent publications that have successfully used the functional brain imaging method known as LORETA. Emphasis is placed on the electrophysiological and neuroanatomical basis of the method, on the localization properties of the method, and on the validation of the method in real experimental human data. Papers that criticize LORETA are briefly discussed. LORETA publications in the 1994-1997 period based localization inference on images of raw electric neuronal activity. In 1998, a series of papers appeared that based localization inference on the statistical parametric mapping methodology applied to high-time resolution LORETA images. Starting in 1999, quantitative neuroanatomy was added to the methodology, based on the digitized Talairach atlas provided by the Brain Imaging Centre, Montreal Neurological Institute. The combination of these methodological developments has placed LORETA at a level that compares favorably to the more classical functional imaging methods, such as PET and fMRI.

  15. Research and Analysis on the Localization of a 3-D Single Source in Lossy Medium Using Uniform Circular Array

    PubMed Central

    Xue, Bing; Qu, Xiaodong; Fang, Guangyou; Ji, Yicai

    2017-01-01

    In this paper, the methods and analysis for estimating the location of a three-dimensional (3-D) single source buried in lossy medium are presented with uniform circular array (UCA). The mathematical model of the signal in the lossy medium is proposed. Using information in the covariance matrix obtained by the sensors’ outputs, equations of the source location (azimuth angle, elevation angle, and range) are obtained. Then, the phase and amplitude of the covariance matrix function are used to process the source localization in the lossy medium. By analyzing the characteristics of the proposed methods and the multiple signal classification (MUSIC) method, the computational complexity and the valid scope of these methods are given. From the results, whether the loss is known or not, we can choose the best method for processing the issues (localization in lossless medium or lossy medium). PMID:28574467

  16. Automated seed localization from CT datasets of the prostate.

    PubMed

    Brinkmann, D H; Kline, R W

    1998-09-01

    With the increasing utilization of permanent brachytherapy implants for treating carcinoma of the prostate, the importance of accurate post-treatment dose calculation also increases for assessing patient outcome and planning future treatments. An automatic method for seed localization of permanent brachytherapy implants, using CT datasets of the prostate, has been developed and tested on a phantom using an actual patient planned seed distribution. This method was also compared to results with the three-film technique for three patient datasets. The automatic method is as accurate or more accurate than the three film technique for 1 mm, 3 mm, and 5 mm contiguous CT slices, and eliminates the inter- and intra-observer variability of the manual methods. The automated method improves the localization of brachytherapy seeds while reducing the time required for the user to input information, and is demonstrated to be less operator dependent, less time consuming, and potentially more accurate than the three-film technique.

  17. An improved local radial point interpolation method for transient heat conduction analysis

    NASA Astrophysics Data System (ADS)

    Wang, Feng; Lin, Gao; Zheng, Bao-Jing; Hu, Zhi-Qiang

    2013-06-01

    The smoothing thin plate spline (STPS) interpolation using the penalty function method according to the optimization theory is presented to deal with transient heat conduction problems. The smooth conditions of the shape functions and derivatives can be satisfied so that the distortions hardly occur. Local weak forms are developed using the weighted residual method locally from the partial differential equations of the transient heat conduction. Here the Heaviside step function is used as the test function in each sub-domain to avoid the need for a domain integral. Essential boundary conditions can be implemented like the finite element method (FEM) as the shape functions possess the Kronecker delta property. The traditional two-point difference method is selected for the time discretization scheme. Three selected numerical examples are presented in this paper to demonstrate the availability and accuracy of the present approach comparing with the traditional thin plate spline (TPS) radial basis functions.

  18. Bounded Linear Stability Analysis - A Time Delay Margin Estimation Approach for Adaptive Control

    NASA Technical Reports Server (NTRS)

    Nguyen, Nhan T.; Ishihara, Abraham K.; Krishnakumar, Kalmanje Srinlvas; Bakhtiari-Nejad, Maryam

    2009-01-01

    This paper presents a method for estimating time delay margin for model-reference adaptive control of systems with almost linear structured uncertainty. The bounded linear stability analysis method seeks to represent the conventional model-reference adaptive law by a locally bounded linear approximation within a small time window using the comparison lemma. The locally bounded linear approximation of the combined adaptive system is cast in a form of an input-time-delay differential equation over a small time window. The time delay margin of this system represents a local stability measure and is computed analytically by a matrix measure method, which provides a simple analytical technique for estimating an upper bound of time delay margin. Based on simulation results for a scalar model-reference adaptive control system, both the bounded linear stability method and the matrix measure method are seen to provide a reasonably accurate and yet not too conservative time delay margin estimation.

  19. A comparison between EEG source localization and fMRI during the processing of emotional visual stimuli

    NASA Astrophysics Data System (ADS)

    Hu, Jin; Tian, Jie; Pan, Xiaohong; Liu, Jiangang

    2007-03-01

    The purpose of this paper is to compare between EEG source localization and fMRI during emotional processing. 108 pictures for EEG (categorized as positive, negative and neutral) and 72 pictures for fMRI were presented to 24 healthy, right-handed subjects. The fMRI data were analyzed using statistical parametric mapping with SPM2. LORETA was applied to grand averaged ERP data to localize intracranial sources. Statistical analysis was implemented to compare spatiotemporal activation of fMRI and EEG. The fMRI results are in accordance with EEG source localization to some extent, while part of mismatch in localization between the two methods was also observed. In the future we should apply the method for simultaneous recording of EEG and fMRI to our study.

  20. Soft sensor modeling based on variable partition ensemble method for nonlinear batch processes

    NASA Astrophysics Data System (ADS)

    Wang, Li; Chen, Xiangguang; Yang, Kai; Jin, Huaiping

    2017-01-01

    Batch processes are always characterized by nonlinear and system uncertain properties, therefore, the conventional single model may be ill-suited. A local learning strategy soft sensor based on variable partition ensemble method is developed for the quality prediction of nonlinear and non-Gaussian batch processes. A set of input variable sets are obtained by bootstrapping and PMI criterion. Then, multiple local GPR models are developed based on each local input variable set. When a new test data is coming, the posterior probability of each best performance local model is estimated based on Bayesian inference and used to combine these local GPR models to get the final prediction result. The proposed soft sensor is demonstrated by applying to an industrial fed-batch chlortetracycline fermentation process.

  1. Wlan-Based Indoor Localization Using Neural Networks

    NASA Astrophysics Data System (ADS)

    Saleem, Fasiha; Wyne, Shurjeel

    2016-07-01

    Wireless indoor localization has generated recent research interest due to its numerous applications. This work investigates Wi-Fi based indoor localization using two variants of the fingerprinting approach. Specifically, we study the application of an artificial neural network (ANN) for implementing the fingerprinting approach and compare its localization performance with a probabilistic fingerprinting method that is based on maximum likelihood estimation (MLE) of the user location. We incorporate spatial correlation of fading into our investigations, which is often neglected in simulation studies and leads to erroneous location estimates. The localization performance is quantified in terms of accuracy, precision, robustness, and complexity. Multiple methods for handling the case of missing APs in online stage are investigated. Our results indicate that ANN-based fingerprinting outperforms the probabilistic approach for all performance metrics considered in this work.

  2. Intracellular Localization of Arabidopsis Sulfurtransferases1

    PubMed Central

    Bauer, Michael; Dietrich, Christof; Nowak, Katharina; Sierralta, Walter D.; Papenbrock, Jutta

    2004-01-01

    Sulfurtransferases (Str) comprise a group of enzymes widely distributed in archaea, eubacteria, and eukaryota which catalyze the transfer of a sulfur atom from suitable sulfur donors to nucleophilic sulfur acceptors. In all organisms analyzed to date, small gene families encoding Str proteins have been identified. The gene products were localized to different compartments of the cells. Our interest concerns the localization of Str proteins encoded in the nuclear genome of Arabidopsis. Computer-based prediction methods revealed localization in different compartments of the cell for six putative AtStrs. Several methods were used to determine the localization of the AtStr proteins experimentally. For AtStr1, a mitochondrial localization was demonstrated by immunodetection in the proteome of isolated mitochondria resolved by one- and two-dimensional gel electrophoresis and subsequent blotting. The respective mature AtStr1 protein was identified by mass spectrometry sequencing. The same result was obtained by transient expression of fusion constructs with the green fluorescent protein in Arabidopsis protoplasts, whereas AtStr2 was exclusively localized to the cytoplasm by this method. Three members of the single-domain AtStr were localized in the chloroplasts as demonstrated by transient expression of green fluorescent protein fusions in protoplasts and stomata, whereas the single-domain AtStr18 was shown to be cytoplasmic. The remarkable subcellular distribution of AtStr15 was additionally analyzed by transmission electron immunomicroscopy using a monospecific antibody against green fluorescent protein, indicating an attachment to the thylakoid membrane. The knowledge of the intracellular localization of the members of this multiprotein family will help elucidate their specific functions in the organism. PMID:15181206

  3. Intracellular localization of Arabidopsis sulfurtransferases.

    PubMed

    Bauer, Michael; Dietrich, Christof; Nowak, Katharina; Sierralta, Walter D; Papenbrock, Jutta

    2004-06-01

    Sulfurtransferases (Str) comprise a group of enzymes widely distributed in archaea, eubacteria, and eukaryota which catalyze the transfer of a sulfur atom from suitable sulfur donors to nucleophilic sulfur acceptors. In all organisms analyzed to date, small gene families encoding Str proteins have been identified. The gene products were localized to different compartments of the cells. Our interest concerns the localization of Str proteins encoded in the nuclear genome of Arabidopsis. Computer-based prediction methods revealed localization in different compartments of the cell for six putative AtStrs. Several methods were used to determine the localization of the AtStr proteins experimentally. For AtStr1, a mitochondrial localization was demonstrated by immunodetection in the proteome of isolated mitochondria resolved by one- and two-dimensional gel electrophoresis and subsequent blotting. The respective mature AtStr1 protein was identified by mass spectrometry sequencing. The same result was obtained by transient expression of fusion constructs with the green fluorescent protein in Arabidopsis protoplasts, whereas AtStr2 was exclusively localized to the cytoplasm by this method. Three members of the single-domain AtStr were localized in the chloroplasts as demonstrated by transient expression of green fluorescent protein fusions in protoplasts and stomata, whereas the single-domain AtStr18 was shown to be cytoplasmic. The remarkable subcellular distribution of AtStr15 was additionally analyzed by transmission electron immunomicroscopy using a monospecific antibody against green fluorescent protein, indicating an attachment to the thylakoid membrane. The knowledge of the intracellular localization of the members of this multiprotein family will help elucidate their specific functions in the organism.

  4. MetaMQAP: a meta-server for the quality assessment of protein models.

    PubMed

    Pawlowski, Marcin; Gajda, Michal J; Matlak, Ryszard; Bujnicki, Janusz M

    2008-09-29

    Computational models of protein structure are usually inaccurate and exhibit significant deviations from the true structure. The utility of models depends on the degree of these deviations. A number of predictive methods have been developed to discriminate between the globally incorrect and approximately correct models. However, only a few methods predict correctness of different parts of computational models. Several Model Quality Assessment Programs (MQAPs) have been developed to detect local inaccuracies in unrefined crystallographic models, but it is not known if they are useful for computational models, which usually exhibit different and much more severe errors. The ability to identify local errors in models was tested for eight MQAPs: VERIFY3D, PROSA, BALA, ANOLEA, PROVE, TUNE, REFINER, PROQRES on 8251 models from the CASP-5 and CASP-6 experiments, by calculating the Spearman's rank correlation coefficients between per-residue scores of these methods and local deviations between C-alpha atoms in the models vs. experimental structures. As a reference, we calculated the value of correlation between the local deviations and trivial features that can be calculated for each residue directly from the models, i.e. solvent accessibility, depth in the structure, and the number of local and non-local neighbours. We found that absolute correlations of scores returned by the MQAPs and local deviations were poor for all methods. In addition, scores of PROQRES and several other MQAPs strongly correlate with 'trivial' features. Therefore, we developed MetaMQAP, a meta-predictor based on a multivariate regression model, which uses scores of the above-mentioned methods, but in which trivial parameters are controlled. MetaMQAP predicts the absolute deviation (in Angströms) of individual C-alpha atoms between the model and the unknown true structure as well as global deviations (expressed as root mean square deviation and GDT_TS scores). Local model accuracy predicted by MetaMQAP shows an impressive correlation coefficient of 0.7 with true deviations from native structures, a significant improvement over all constituent primary MQAP scores. The global MetaMQAP score is correlated with model GDT_TS on the level of 0.89. Finally, we compared our method with the MQAPs that scored best in the 7th edition of CASP, using CASP7 server models (not included in the MetaMQAP training set) as the test data. In our benchmark, MetaMQAP is outperformed only by PCONS6 and method QA_556 - methods that require comparison of multiple alternative models and score each of them depending on its similarity to other models. MetaMQAP is however the best among methods capable of evaluating just single models. We implemented the MetaMQAP as a web server available for free use by all academic users at the URL https://genesilico.pl/toolkit/

  5. "I Think Boys Would Rather Be Alpha Male": Being Male and Sexual Health Experiences of Young Men from a Deprived Area in the UK

    ERIC Educational Resources Information Center

    Watkins, F.; Bristow, K.; Robertson, S.; Norman, R.; Litva, A.; Stanistreet, D.

    2013-01-01

    Objective: To explore the experiences of young men aged 16-19, living in an area of high deprivation, when accessing local sexual health services. Design: A qualitative design drawing on ethnographic methods. Setting: A local college. Methods: A multi-method approach was adopted using: one-to-one semi-structured interviews with young men and…

  6. A singular-value method for reconstruction of nonradial and lossy objects.

    PubMed

    Jiang, Wei; Astheimer, Jeffrey; Waag, Robert

    2012-03-01

    Efficient inverse scattering algorithms for nonradial lossy objects are presented using singular-value decomposition to form reduced-rank representations of the scattering operator. These algorithms extend eigenfunction methods that are not applicable to nonradial lossy scattering objects because the scattering operators for these objects do not have orthonormal eigenfunction decompositions. A method of local reconstruction by segregation of scattering contributions from different local regions is also presented. Scattering from each region is isolated by forming a reduced-rank representation of the scattering operator that has domain and range spaces comprised of far-field patterns with retransmitted fields that focus on the local region. Methods for the estimation of the boundary, average sound speed, and average attenuation slope of the scattering object are also given. These methods yielded approximations of scattering objects that were sufficiently accurate to allow residual variations to be reconstructed in a single iteration. Calculated scattering from a lossy elliptical object with a random background, internal features, and white noise is used to evaluate the proposed methods. Local reconstruction yielded images with spatial resolution that is finer than a half wavelength of the center frequency and reproduces sound speed and attenuation slope with relative root-mean-square errors of 1.09% and 11.45%, respectively.

  7. Assessment of local pulse wave velocity distribution in mice using k-t BLAST PC-CMR with semi-automatic area segmentation.

    PubMed

    Herold, Volker; Herz, Stefan; Winter, Patrick; Gutjahr, Fabian Tobias; Andelovic, Kristina; Bauer, Wolfgang Rudolf; Jakob, Peter Michael

    2017-10-16

    Local aortic pulse wave velocity (PWV) is a measure for vascular stiffness and has a predictive value for cardiovascular events. Ultra high field CMR scanners allow the quantification of local PWV in mice, however these systems are yet unable to monitor the distribution of local elasticities. In the present study we provide a new accelerated method to quantify local aortic PWV in mice with phase-contrast cardiovascular magnetic resonance imaging (PC-CMR) at 17.6 T. Based on a k-t BLAST (Broad-use Linear Acquisition Speed-up Technique) undersampling scheme, total measurement time could be reduced by a factor of 6. The fast data acquisition enables to quantify the local PWV at several locations along the aortic blood vessel based on the evaluation of local temporal changes in blood flow and vessel cross sectional area. To speed up post processing and to eliminate operator bias, we introduce a new semi-automatic segmentation algorithm to quantify cross-sectional areas of the aortic vessel. The new methods were applied in 10 eight-month-old mice (4 C57BL/6J-mice and 6 ApoE (-/-) -mice) at 12 adjacent locations along the abdominal aorta. Accelerated data acquisition and semi-automatic post-processing delivered reliable measures for the local PWV, similiar to those obtained with full data sampling and manual segmentation. No statistically significant differences of the mean values could be detected for the different measurement approaches. Mean PWV values were elevated for the ApoE (-/-) -group compared to the C57BL/6J-group (3.5 ± 0.7 m/s vs. 2.2 ± 0.4 m/s, p < 0.01). A more heterogeneous PWV-distribution in the ApoE (-/-) -animals could be observed compared to the C57BL/6J-mice, representing the local character of lesion development in atherosclerosis. In the present work, we showed that k-t BLAST PC-MRI enables the measurement of the local PWV distribution in the mouse aorta. The semi-automatic segmentation method based on PC-CMR data allowed rapid determination of local PWV. The findings of this study demonstrate the ability of the proposed methods to non-invasively quantify the spatial variations in local PWV along the aorta of ApoE (-/-) -mice as a relevant model of atherosclerosis.

  8. Estimation of Local Bone Loads for the Volume of Interest.

    PubMed

    Kim, Jung Jin; Kim, Youkyung; Jang, In Gwun

    2016-07-01

    Computational bone remodeling simulations have recently received significant attention with the aid of state-of-the-art high-resolution imaging modalities. They have been performed using localized finite element (FE) models rather than full FE models due to the excessive computational costs of full FE models. However, these localized bone remodeling simulations remain to be investigated in more depth. In particular, applying simplified loading conditions (e.g., uniform and unidirectional loads) to localized FE models have a severe limitation in a reliable subject-specific assessment. In order to effectively determine the physiological local bone loads for the volume of interest (VOI), this paper proposes a novel method of estimating the local loads when the global musculoskeletal loads are given. The proposed method is verified for the three VOI in a proximal femur in terms of force equilibrium, displacement field, and strain energy density (SED) distribution. The effect of the global load deviation on the local load estimation is also investigated by perturbing a hip joint contact force (HCF) in the femoral head. Deviation in force magnitude exhibits the greatest absolute changes in a SED distribution due to its own greatest deviation, whereas angular deviation perpendicular to a HCF provides the greatest relative change. With further in vivo force measurements and high-resolution clinical imaging modalities, the proposed method will contribute to the development of reliable patient-specific localized FE models, which can provide enhanced computational efficiency for iterative computing processes such as bone remodeling simulations.

  9. MR-based source localization for MR-guided HDR brachytherapy

    NASA Astrophysics Data System (ADS)

    Beld, E.; Moerland, M. A.; Zijlstra, F.; Viergever, M. A.; Lagendijk, J. J. W.; Seevinck, P. R.

    2018-04-01

    For the purpose of MR-guided high-dose-rate (HDR) brachytherapy, a method for real-time localization of an HDR brachytherapy source was developed, which requires high spatial and temporal resolutions. MR-based localization of an HDR source serves two main aims. First, it enables real-time treatment verification by determination of the HDR source positions during treatment. Second, when using a dummy source, MR-based source localization provides an automatic detection of the source dwell positions after catheter insertion, allowing elimination of the catheter reconstruction procedure. Localization of the HDR source was conducted by simulation of the MR artifacts, followed by a phase correlation localization algorithm applied to the MR images and the simulated images, to determine the position of the HDR source in the MR images. To increase the temporal resolution of the MR acquisition, the spatial resolution was decreased, and a subpixel localization operation was introduced. Furthermore, parallel imaging (sensitivity encoding) was applied to further decrease the MR scan time. The localization method was validated by a comparison with CT, and the accuracy and precision were investigated. The results demonstrated that the described method could be used to determine the HDR source position with a high accuracy (0.4–0.6 mm) and a high precision (⩽0.1 mm), at high temporal resolutions (0.15–1.2 s per slice). This would enable real-time treatment verification as well as an automatic detection of the source dwell positions.

  10. Estimating the financial resources needed for local public health departments in Minnesota: a multimethod approach.

    PubMed

    Riley, William; Briggs, Jill; McCullough, Mac

    2011-01-01

    This study presents a model for determining total funding needed for individual local health departments. The aim is to determine the financial resources needed to provide services for statewide local public health departments in Minnesota based on a gaps analysis done to estimate the funding needs. We used a multimethod analysis consisting of 3 approaches to estimate gaps in local public health funding consisting of (1) interviews of selected local public health leaders, (2) a Delphi panel, and (3) a Nominal Group Technique. On the basis of these 3 approaches, a consensus estimate of funding gaps was generated for statewide projections. The study includes an analysis of cost, performance, and outcomes from 2005 to 2007 for all 87 local governmental health departments in Minnesota. For each of the methods, we selected a panel to represent a profile of Minnesota health departments. The 2 main outcome measures were local-level gaps in financial resources and total resources needed to provide public health services at the local level. The total public health expenditure in Minnesota for local governmental public health departments was $302 million in 2007 ($58.92 per person). The consensus estimate of the financial gaps in local public health departments indicates that an additional $32.5 million (a 10.7% increase or $6.32 per person) is needed to adequately serve public health needs in the local communities. It is possible to make informed estimates of funding gaps for public health activities on the basis of a combination of quantitative methods. There is a wide variation in public health expenditure at the local levels, and methods are needed to establish minimum baseline expenditure levels to adequately treat a population. The gaps analysis can be used by stakeholders to inform policy makers of the need for improved funding of the public health system.

  11. Method and apparatus of assessing down-hole drilling conditions

    DOEpatents

    Hall, David R [Provo, UT; Pixton, David S [Lehl, UT; Johnson, Monte L [Orem, UT; Bartholomew, David B [Springville, UT; Fox, Joe [Spanish Fork, UT

    2007-04-24

    A method and apparatus for use in assessing down-hole drilling conditions are disclosed. The apparatus includes a drill string, a plurality of sensors, a computing device, and a down-hole network. The sensors are distributed along the length of the drill string and are capable of sensing localized down-hole conditions while drilling. The computing device is coupled to at least one sensor of the plurality of sensors. The data is transmitted from the sensors to the computing device over the down-hole network. The computing device analyzes data output by the sensors and representative of the sensed localized conditions to assess the down-hole drilling conditions. The method includes sensing localized drilling conditions at a plurality of points distributed along the length of a drill string during drilling operations; transmitting data representative of the sensed localized conditions to a predetermined location; and analyzing the transmitted data to assess the down-hole drilling conditions.

  12. Local Descriptors of Dynamic and Nondynamic Correlation.

    PubMed

    Ramos-Cordoba, Eloy; Matito, Eduard

    2017-06-13

    Quantitatively accurate electronic structure calculations rely on the proper description of electron correlation. A judicious choice of the approximate quantum chemistry method depends upon the importance of dynamic and nondynamic correlation, which is usually assesed by scalar measures. Existing measures of electron correlation do not consider separately the regions of the Cartesian space where dynamic or nondynamic correlation are most important. We introduce real-space descriptors of dynamic and nondynamic electron correlation that admit orbital decomposition. Integration of the local descriptors yields global numbers that can be used to quantify dynamic and nondynamic correlation. Illustrative examples over different chemical systems with varying electron correlation regimes are used to demonstrate the capabilities of the local descriptors. Since the expressions only require orbitals and occupation numbers, they can be readily applied in the context of local correlation methods, hybrid methods, density matrix functional theory, and fractional-occupancy density functional theory.

  13. Error Estimation for the Linearized Auto-Localization Algorithm

    PubMed Central

    Guevara, Jorge; Jiménez, Antonio R.; Prieto, Jose Carlos; Seco, Fernando

    2012-01-01

    The Linearized Auto-Localization (LAL) algorithm estimates the position of beacon nodes in Local Positioning Systems (LPSs), using only the distance measurements to a mobile node whose position is also unknown. The LAL algorithm calculates the inter-beacon distances, used for the estimation of the beacons’ positions, from the linearized trilateration equations. In this paper we propose a method to estimate the propagation of the errors of the inter-beacon distances obtained with the LAL algorithm, based on a first order Taylor approximation of the equations. Since the method depends on such approximation, a confidence parameter τ is defined to measure the reliability of the estimated error. Field evaluations showed that by applying this information to an improved weighted-based auto-localization algorithm (WLAL), the standard deviation of the inter-beacon distances can be improved by more than 30% on average with respect to the original LAL method. PMID:22736965

  14. Nodal Diffusion Burnable Poison Treatment for Prismatic Reactor Cores

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    A. M. Ougouag; R. M. Ferrer

    2010-10-01

    The prismatic block version of the High Temperature Reactor (HTR) considered as a candidate Very High Temperature Reactor (VHTR)design may use burnable poison pins in locations at some corners of the fuel blocks (i.e., assembly equivalent structures). The presence of any highly absorbing materials, such as these burnable poisons, within fuel blocks for hexagonal geometry, graphite-moderated High Temperature Reactors (HTRs) causes a local inter-block flux depression that most nodal diffusion-based method have failed to properly model or otherwise represent. The location of these burnable poisons near vertices results in an asymmetry in the morphology of the assemblies (or blocks). Hencemore » the resulting inadequacy of traditional homogenization methods, as these “spread” the actually local effect of the burnable poisons throughout the assembly. Furthermore, the actual effect of the burnable poison is primarily local with influence in its immediate vicinity, which happens to include a small region within the same assembly as well as similar regions in the adjacent assemblies. Traditional homogenization methods miss this artifact entirely. This paper presents a novel method for treating the local effect of the burnable poison explicitly in the context of a modern nodal method.« less

  15. Children's behavioral pain reactions during local anesthetic injection using cotton-roll vibration method compared with routine topical anesthesia: A randomized controlled trial.

    PubMed

    Bagherian, Ali; Sheikhfathollahi, Mahmood

    2016-01-01

    Topical anesthesia has been widely advocated as an important component of atraumatic administration of intraoral local anesthesia. The aim of this study was to use direct observation of children's behavioral pain reactions during local anesthetic injection using cotton-roll vibration method compared with routine topical anesthesia. Forty-eight children participated in this randomized controlled clinical trial. They received two separate inferior alveolar nerve block or primary maxillary molar infiltration injections on contralateral sides of the jaws by both cotton-roll vibration (a combination of topical anesthesia gel, cotton roll, and vibration for physical distraction) and control (routine topical anesthesia) methods. Behavioral pain reactions of children were measured according to the author-developed face, head, foot, hand, trunk, and cry (FHFHTC) scale, resulting in total scores between 0 and 18. The total scores on the FHFHTC scale ranged between 0-5 and 0-10 in the cotton-roll vibration and control methods, respectively. The mean ± standard deviation values of total scores on FHFHTC scale were lower in the cotton-roll vibration method (1.21 ± 1.38) than in control method (2.44 ± 2.18), and this was statistically significant (P < 0.001). It may be concluded that the cotton-roll vibration method can be more helpful than the routine topical anesthesia in reducing behavioral pain reactions in children during local anesthesia administration.

  16. Overlapping communities from dense disjoint and high total degree clusters

    NASA Astrophysics Data System (ADS)

    Zhang, Hongli; Gao, Yang; Zhang, Yue

    2018-04-01

    Community plays an important role in the field of sociology, biology and especially in domains of computer science, where systems are often represented as networks. And community detection is of great importance in the domains. A community is a dense subgraph of the whole graph with more links between its members than between its members to the outside nodes, and nodes in the same community probably share common properties or play similar roles in the graph. Communities overlap when nodes in a graph belong to multiple communities. A vast variety of overlapping community detection methods have been proposed in the literature, and the local expansion method is one of the most successful techniques dealing with large networks. The paper presents a density-based seeding method, in which dense disjoint local clusters are searched and selected as seeds. The proposed method selects a seed by the total degree and density of local clusters utilizing merely local structures of the network. Furthermore, this paper proposes a novel community refining phase via minimizing the conductance of each community, through which the quality of identified communities is largely improved in linear time. Experimental results in synthetic networks show that the proposed seeding method outperforms other seeding methods in the state of the art and the proposed refining method largely enhances the quality of the identified communities. Experimental results in real graphs with ground-truth communities show that the proposed approach outperforms other state of the art overlapping community detection algorithms, in particular, it is more than two orders of magnitude faster than the existing global algorithms with higher quality, and it obtains much more accurate community structure than the current local algorithms without any priori information.

  17. Local statistics adaptive entropy coding method for the improvement of H.26L VLC coding

    NASA Astrophysics Data System (ADS)

    Yoo, Kook-yeol; Kim, Jong D.; Choi, Byung-Sun; Lee, Yung Lyul

    2000-05-01

    In this paper, we propose an adaptive entropy coding method to improve the VLC coding efficiency of H.26L TML-1 codec. First of all, we will show that the VLC coding presented in TML-1 does not satisfy the sibling property of entropy coding. Then, we will modify the coding method into the local statistics adaptive one to satisfy the property. The proposed method based on the local symbol statistics dynamically changes the mapping relationship between symbol and bit pattern in the VLC table according to sibling property. Note that the codewords in the VLC table of TML-1 codec is not changed. Since this changed mapping relationship also derived in the decoder side by using the decoded symbols, the proposed VLC coding method does not require any overhead information. The simulation results show that the proposed method gives about 30% and 37% reduction in average bit rate for MB type and CBP information, respectively.

  18. Influence of Intracranial Electrode Density and Spatial Configuration on Interictal Spike Localization: A Case Study.

    PubMed

    Lie, Octavian V; Papanastassiou, Alexander M; Cavazos, José E; Szabó, Ákos C

    2015-10-01

    Poor seizure outcomes after epilepsy surgery often reflect an incorrect localization of the epileptic sources by standard intracranial EEG interpretation because of limited electrode coverage of the epileptogenic zone. This study investigates whether, in such conditions, source modeling is able to provide more accurate source localization than the standard clinical method that can be used prospectively to improve surgical resection planning. Suboptimal epileptogenic zone sampling is simulated by subsets of the electrode configuration used to record intracranial EEG in a patient rendered seizure free after surgery. sLORETA and the clinical method solutions are applied to interictal spikes sampled with these electrode subsets and are compared for colocalization with the resection volume and displacement due to electrode downsampling. sLORETA provides often congruent and at times more accurate source localization when compared with the standard clinical method. However, with electrode downsampling, individual sLORETA solution locations can vary considerably and shift consistently toward the remaining electrodes. sLORETA application can improve source localization based on the clinical method but does not reliably compensate for suboptimal electrode placement. Incorporating sLORETA solutions based on intracranial EEG in surgical planning should proceed cautiously in cases where electrode repositioning is planned on clinical grounds.

  19. Localized Statistics for DW-MRI Fiber Bundle Segmentation

    PubMed Central

    Lankton, Shawn; Melonakos, John; Malcolm, James; Dambreville, Samuel; Tannenbaum, Allen

    2013-01-01

    We describe a method for segmenting neural fiber bundles in diffusion-weighted magnetic resonance images (DWMRI). As these bundles traverse the brain to connect regions, their local orientation of diffusion changes drastically, hence a constant global model is inaccurate. We propose a method to compute localized statistics on orientation information and use it to drive a variational active contour segmentation that accurately models the non-homogeneous orientation information present along the bundle. Initialized from a single fiber path, the proposed method proceeds to capture the entire bundle. We demonstrate results using the technique to segment the cingulum bundle and describe several extensions making the technique applicable to a wide range of tissues. PMID:23652079

  20. Continuous Space Estimation: Increasing WiFi-Based Indoor Localization Resolution without Increasing the Site-Survey Effort.

    PubMed

    Hernández, Noelia; Ocaña, Manuel; Alonso, Jose M; Kim, Euntai

    2017-01-13

    Although much research has taken place in WiFi indoor localization systems, their accuracy can still be improved. When designing this kind of system, fingerprint-based methods are a common choice. The problem with fingerprint-based methods comes with the need of site surveying the environment, which is effort consuming. In this work, we propose an approach, based on support vector regression, to estimate the received signal strength at non-site-surveyed positions of the environment. Experiments, performed in a real environment, show that the proposed method could be used to improve the resolution of fingerprint-based indoor WiFi localization systems without increasing the site survey effort.

  1. Continuous Space Estimation: Increasing WiFi-Based Indoor Localization Resolution without Increasing the Site-Survey Effort †

    PubMed Central

    Hernández, Noelia; Ocaña, Manuel; Alonso, Jose M.; Kim, Euntai

    2017-01-01

    Although much research has taken place in WiFi indoor localization systems, their accuracy can still be improved. When designing this kind of system, fingerprint-based methods are a common choice. The problem with fingerprint-based methods comes with the need of site surveying the environment, which is effort consuming. In this work, we propose an approach, based on support vector regression, to estimate the received signal strength at non-site-surveyed positions of the environment. Experiments, performed in a real environment, show that the proposed method could be used to improve the resolution of fingerprint-based indoor WiFi localization systems without increasing the site survey effort. PMID:28098773

  2. Face Alignment via Regressing Local Binary Features.

    PubMed

    Ren, Shaoqing; Cao, Xudong; Wei, Yichen; Sun, Jian

    2016-03-01

    This paper presents a highly efficient and accurate regression approach for face alignment. Our approach has two novel components: 1) a set of local binary features and 2) a locality principle for learning those features. The locality principle guides us to learn a set of highly discriminative local binary features for each facial landmark independently. The obtained local binary features are used to jointly learn a linear regression for the final output. This approach achieves the state-of-the-art results when tested on the most challenging benchmarks to date. Furthermore, because extracting and regressing local binary features are computationally very cheap, our system is much faster than previous methods. It achieves over 3000 frames per second (FPS) on a desktop or 300 FPS on a mobile phone for locating a few dozens of landmarks. We also study a key issue that is important but has received little attention in the previous research, which is the face detector used to initialize alignment. We investigate several face detectors and perform quantitative evaluation on how they affect alignment accuracy. We find that an alignment friendly detector can further greatly boost the accuracy of our alignment method, reducing the error up to 16% relatively. To facilitate practical usage of face detection/alignment methods, we also propose a convenient metric to measure how good a detector is for alignment initialization.

  3. Medical image classification using spatial adjacent histogram based on adaptive local binary patterns.

    PubMed

    Liu, Dong; Wang, Shengsheng; Huang, Dezhi; Deng, Gang; Zeng, Fantao; Chen, Huiling

    2016-05-01

    Medical image recognition is an important task in both computer vision and computational biology. In the field of medical image classification, representing an image based on local binary patterns (LBP) descriptor has become popular. However, most existing LBP-based methods encode the binary patterns in a fixed neighborhood radius and ignore the spatial relationships among local patterns. The ignoring of the spatial relationships in the LBP will cause a poor performance in the process of capturing discriminative features for complex samples, such as medical images obtained by microscope. To address this problem, in this paper we propose a novel method to improve local binary patterns by assigning an adaptive neighborhood radius for each pixel. Based on these adaptive local binary patterns, we further propose a spatial adjacent histogram strategy to encode the micro-structures for image representation. An extensive set of evaluations are performed on four medical datasets which show that the proposed method significantly improves standard LBP and compares favorably with several other prevailing approaches. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Large margin nearest neighbor classifiers.

    PubMed

    Domeniconi, Carlotta; Gunopulos, Dimitrios; Peng, Jing

    2005-07-01

    The nearest neighbor technique is a simple and appealing approach to addressing classification problems. It relies on the assumption of locally constant class conditional probabilities. This assumption becomes invalid in high dimensions with a finite number of examples due to the curse of dimensionality. Severe bias can be introduced under these conditions when using the nearest neighbor rule. The employment of a locally adaptive metric becomes crucial in order to keep class conditional probabilities close to uniform, thereby minimizing the bias of estimates. We propose a technique that computes a locally flexible metric by means of support vector machines (SVMs). The decision function constructed by SVMs is used to determine the most discriminant direction in a neighborhood around the query. Such a direction provides a local feature weighting scheme. We formally show that our method increases the margin in the weighted space where classification takes place. Moreover, our method has the important advantage of online computational efficiency over competing locally adaptive techniques for nearest neighbor classification. We demonstrate the efficacy of our method using both real and simulated data.

  5. Near-isotropic 3D optical nanoscopy with photon-limited chromophores

    PubMed Central

    Tang, Jianyong; Akerboom, Jasper; Vaziri, Alipasha; Looger, Loren L.; Shank, Charles V.

    2010-01-01

    Imaging approaches based on single molecule localization break the diffraction barrier of conventional fluorescence microscopy, allowing for bioimaging with nanometer resolution. It remains a challenge, however, to precisely localize photon-limited single molecules in 3D. We have developed a new localization-based imaging technique achieving almost isotropic subdiffraction resolution in 3D. A tilted mirror is used to generate a side view in addition to the front view of activated single emitters, allowing their 3D localization to be precisely determined for superresolution imaging. Because both front and side views are in focus, this method is able to efficiently collect emitted photons. The technique is simple to implement on a commercial fluorescence microscope, and especially suitable for biological samples with photon-limited chromophores such as endogenously expressed photoactivatable fluorescent proteins. Moreover, this method is relatively resistant to optical aberration, as it requires only centroid determination for localization analysis. Here we demonstrate the application of this method to 3D imaging of bacterial protein distribution and neuron dendritic morphology with subdiffraction resolution. PMID:20472826

  6. The collection of images of an insulator taken outdoors in varying lighting conditions with additional laser spots.

    PubMed

    Tomaszewski, Michał; Ruszczak, Bogdan; Michalski, Paweł

    2018-06-01

    Electrical insulators are elements of power lines that require periodical diagnostics. Due to their location on the components of high-voltage power lines, their imaging can be cumbersome and time-consuming, especially under varying lighting conditions. Insulator diagnostics with the use of visual methods may require localizing insulators in the scene. Studies focused on insulator localization in the scene apply a number of methods, including: texture analysis, MRF (Markov Random Field), Gabor filters or GLCM (Gray Level Co-Occurrence Matrix) [1], [2]. Some methods, e.g. those which localize insulators based on colour analysis [3], rely on object and scene illumination, which is why the images from the dataset are taken under varying lighting conditions. The dataset may also be used to compare the effectiveness of different methods of localizing insulators in images. This article presents high-resolution images depicting a long rod electrical insulator under varying lighting conditions and against different backgrounds: crops, forest and grass. The dataset contains images with visible laser spots (generated by a device emitting light at the wavelength of 532 nm) and images without such spots, as well as complementary data concerning the illumination level and insulator position in the scene, the number of registered laser spots, and their coordinates in the image. The laser spots may be used to support object-localizing algorithms, while the images without spots may serve as a source of information for those algorithms which do not need spots to localize an insulator.

  7. Synthesis in land change science: methodological patterns, challenges, and guidelines.

    PubMed

    Magliocca, Nicholas R; Rudel, Thomas K; Verburg, Peter H; McConnell, William J; Mertz, Ole; Gerstner, Katharina; Heinimann, Andreas; Ellis, Erle C

    Global and regional economic and environmental changes are increasingly influencing local land-use, livelihoods, and ecosystems. At the same time, cumulative local land changes are driving global and regional changes in biodiversity and the environment. To understand the causes and consequences of these changes, land change science (LCS) draws on a wide array synthetic and meta-study techniques to generate global and regional knowledge from local case studies of land change. Here, we review the characteristics and applications of synthesis methods in LCS and assess the current state of synthetic research based on a meta-analysis of synthesis studies from 1995 to 2012. Publication of synthesis research is accelerating, with a clear trend toward increasingly sophisticated and quantitative methods, including meta-analysis. Detailed trends in synthesis objectives, methods, and land change phenomena and world regions most commonly studied are presented. Significant challenges to successful synthesis research in LCS are also identified, including issues of interpretability and comparability across case-studies and the limits of and biases in the geographic coverage of case studies. Nevertheless, synthesis methods based on local case studies will remain essential for generating systematic global and regional understanding of local land change for the foreseeable future, and multiple opportunities exist to accelerate and enhance the reliability of synthetic LCS research in the future. Demand for global and regional knowledge generation will continue to grow to support adaptation and mitigation policies consistent with both the local realities and regional and global environmental and economic contexts of land change.

  8. Robust hashing with local models for approximate similarity search.

    PubMed

    Song, Jingkuan; Yang, Yi; Li, Xuelong; Huang, Zi; Yang, Yang

    2014-07-01

    Similarity search plays an important role in many applications involving high-dimensional data. Due to the known dimensionality curse, the performance of most existing indexing structures degrades quickly as the feature dimensionality increases. Hashing methods, such as locality sensitive hashing (LSH) and its variants, have been widely used to achieve fast approximate similarity search by trading search quality for efficiency. However, most existing hashing methods make use of randomized algorithms to generate hash codes without considering the specific structural information in the data. In this paper, we propose a novel hashing method, namely, robust hashing with local models (RHLM), which learns a set of robust hash functions to map the high-dimensional data points into binary hash codes by effectively utilizing local structural information. In RHLM, for each individual data point in the training dataset, a local hashing model is learned and used to predict the hash codes of its neighboring data points. The local models from all the data points are globally aligned so that an optimal hash code can be assigned to each data point. After obtaining the hash codes of all the training data points, we design a robust method by employing l2,1 -norm minimization on the loss function to learn effective hash functions, which are then used to map each database point into its hash code. Given a query data point, the search process first maps it into the query hash code by the hash functions and then explores the buckets, which have similar hash codes to the query hash code. Extensive experimental results conducted on real-life datasets show that the proposed RHLM outperforms the state-of-the-art methods in terms of search quality and efficiency.

  9. Estimating the Impacts of Local Policy Innovation: The Synthetic Control Method Applied to Tropical Deforestation

    PubMed Central

    Sills, Erin O.; Herrera, Diego; Kirkpatrick, A. Justin; Brandão, Amintas; Dickson, Rebecca; Hall, Simon; Pattanayak, Subhrendu; Shoch, David; Vedoveto, Mariana; Young, Luisa; Pfaff, Alexander

    2015-01-01

    Quasi-experimental methods increasingly are used to evaluate the impacts of conservation interventions by generating credible estimates of counterfactual baselines. These methods generally require large samples for statistical comparisons, presenting a challenge for evaluating innovative policies implemented within a few pioneering jurisdictions. Single jurisdictions often are studied using comparative methods, which rely on analysts’ selection of best case comparisons. The synthetic control method (SCM) offers one systematic and transparent way to select cases for comparison, from a sizeable pool, by focusing upon similarity in outcomes before the intervention. We explain SCM, then apply it to one local initiative to limit deforestation in the Brazilian Amazon. The municipality of Paragominas launched a multi-pronged local initiative in 2008 to maintain low deforestation while restoring economic production. This was a response to having been placed, due to high deforestation, on a federal “blacklist” that increased enforcement of forest regulations and restricted access to credit and output markets. The local initiative included mapping and monitoring of rural land plus promotion of economic alternatives compatible with low deforestation. The key motivation for the program may have been to reduce the costs of blacklisting. However its stated purpose was to limit deforestation, and thus we apply SCM to estimate what deforestation would have been in a (counterfactual) scenario of no local initiative. We obtain a plausible estimate, in that deforestation patterns before the intervention were similar in Paragominas and the synthetic control, which suggests that after several years, the initiative did lower deforestation (significantly below the synthetic control in 2012). This demonstrates that SCM can yield helpful land-use counterfactuals for single units, with opportunities to integrate local and expert knowledge and to test innovations and permutations on policies that are implemented in just a few locations. PMID:26173108

  10. Estimating the Impacts of Local Policy Innovation: The Synthetic Control Method Applied to Tropical Deforestation.

    PubMed

    Sills, Erin O; Herrera, Diego; Kirkpatrick, A Justin; Brandão, Amintas; Dickson, Rebecca; Hall, Simon; Pattanayak, Subhrendu; Shoch, David; Vedoveto, Mariana; Young, Luisa; Pfaff, Alexander

    2015-01-01

    Quasi-experimental methods increasingly are used to evaluate the impacts of conservation interventions by generating credible estimates of counterfactual baselines. These methods generally require large samples for statistical comparisons, presenting a challenge for evaluating innovative policies implemented within a few pioneering jurisdictions. Single jurisdictions often are studied using comparative methods, which rely on analysts' selection of best case comparisons. The synthetic control method (SCM) offers one systematic and transparent way to select cases for comparison, from a sizeable pool, by focusing upon similarity in outcomes before the intervention. We explain SCM, then apply it to one local initiative to limit deforestation in the Brazilian Amazon. The municipality of Paragominas launched a multi-pronged local initiative in 2008 to maintain low deforestation while restoring economic production. This was a response to having been placed, due to high deforestation, on a federal "blacklist" that increased enforcement of forest regulations and restricted access to credit and output markets. The local initiative included mapping and monitoring of rural land plus promotion of economic alternatives compatible with low deforestation. The key motivation for the program may have been to reduce the costs of blacklisting. However its stated purpose was to limit deforestation, and thus we apply SCM to estimate what deforestation would have been in a (counterfactual) scenario of no local initiative. We obtain a plausible estimate, in that deforestation patterns before the intervention were similar in Paragominas and the synthetic control, which suggests that after several years, the initiative did lower deforestation (significantly below the synthetic control in 2012). This demonstrates that SCM can yield helpful land-use counterfactuals for single units, with opportunities to integrate local and expert knowledge and to test innovations and permutations on policies that are implemented in just a few locations.

  11. The contactless detection of local normal transitions in superconducting coils by using Poynting’s vector method

    NASA Astrophysics Data System (ADS)

    Habu, K.; Kaminohara, S.; Kimoto, T.; Kawagoe, A.; Sumiyoshi, F.; Okamoto, H.

    2010-11-01

    We have developed a new monitoring system to detect an unusual event in the superconducting coils without direct contact on the coils, using Poynting's vector method. In this system, the potential leads and pickup coils are set around the superconducting coils to measure local electric and magnetic fields, respectively. By measuring the sets of magnetic and electric fields, the Poynting's vectors around the coil can be obtained. An unusual event in the coil can be detected as the result of the change of the Poynting's vector. This system has no risk of the voltage breakdown which may happen with the balance voltage method, because there is no need of direct contacts on the coil windings. In a previous paper, we have demonstrated that our system can detect the normal transitions in the Bi-2223 coil without direct contact on the coil windings by using a small test system. For our system to be applied to practical devices, it is necessary for the early detection of an unusual event in the coils to be able to detect local normal transitions in the coils. The signal voltages of the small sensors to measure local magnetic and electric fields are small. Although the increase in signals of the pickup coils is attained easily by an increase in the number of turns of the pickup coils, an increase in the signals of the potential lead is not easily attained. In this paper, a new method to amplify the signal of local electric fields around the coil is proposed. The validity of the method has been confirmed by measuring local electric fields around the Bi-2223 coil.

  12. 77 FR 24247 - 60-Day Notice of Proposed Information Collection: DS-5506, Local U.S. Citizen Skills/Resources...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-23

    ..., Local U.S. Citizen Skills/Resources Survey ACTION: Notice of request for public comments. SUMMARY: The... of 1995. Title of Information Collection: Local U.S. Citizen Skills/Resources Survey. OMB Control... Collection The Local U.S. Citizen Skills/Resources Survey is a systematic method of gathering information...

  13. Integrated Detection and Prediction of Influenza Activity for Real-Time Surveillance: Algorithm Design

    PubMed Central

    2017-01-01

    Background Influenza is a viral respiratory disease capable of causing epidemics that represent a threat to communities worldwide. The rapidly growing availability of electronic “big data” from diagnostic and prediagnostic sources in health care and public health settings permits advance of a new generation of methods for local detection and prediction of winter influenza seasons and influenza pandemics. Objective The aim of this study was to present a method for integrated detection and prediction of influenza virus activity in local settings using electronically available surveillance data and to evaluate its performance by retrospective application on authentic data from a Swedish county. Methods An integrated detection and prediction method was formally defined based on a design rationale for influenza detection and prediction methods adapted for local surveillance. The novel method was retrospectively applied on data from the winter influenza season 2008-09 in a Swedish county (population 445,000). Outcome data represented individuals who met a clinical case definition for influenza (based on International Classification of Diseases version 10 [ICD-10] codes) from an electronic health data repository. Information from calls to a telenursing service in the county was used as syndromic data source. Results The novel integrated detection and prediction method is based on nonmechanistic statistical models and is designed for integration in local health information systems. The method is divided into separate modules for detection and prediction of local influenza virus activity. The function of the detection module is to alert for an upcoming period of increased load of influenza cases on local health care (using influenza-diagnosis data), whereas the function of the prediction module is to predict the timing of the activity peak (using syndromic data) and its intensity (using influenza-diagnosis data). For detection modeling, exponential regression was used based on the assumption that the beginning of a winter influenza season has an exponential growth of infected individuals. For prediction modeling, linear regression was applied on 7-day periods at the time in order to find the peak timing, whereas a derivate of a normal distribution density function was used to find the peak intensity. We found that the integrated detection and prediction method detected the 2008-09 winter influenza season on its starting day (optimal timeliness 0 days), whereas the predicted peak was estimated to occur 7 days ahead of the factual peak and the predicted peak intensity was estimated to be 26% lower than the factual intensity (6.3 compared with 8.5 influenza-diagnosis cases/100,000). Conclusions Our detection and prediction method is one of the first integrated methods specifically designed for local application on influenza data electronically available for surveillance. The performance of the method in a retrospective study indicates that further prospective evaluations of the methods are justified. PMID:28619700

  14. Methods of Selecting Industries for Depressed Areas--An Introduction to Feasibility Studies. Developing Job Opportunities 2.

    ERIC Educational Resources Information Center

    Klaassen, Leo H.

    This report presents severl alternative methods which may be employed by local authorities in identifying likely prospects for local industrialization, and describes a specialized input-output technique to define inter-industry relations and inter-regional relations of industries. This technique is applied, for illustrative purposes, to three…

  15. Nonstandard Methods in Lie Theory

    ERIC Educational Resources Information Center

    Goldbring, Isaac Martin

    2009-01-01

    In this thesis, we apply model theory to Lie theory and geometric group theory. These applications of model theory come via nonstandard analysis. In Lie theory, we use nonstandard methods to prove two results. First, we give a positive solution to the local form of Hilbert's Fifth Problem, which asks whether every locally euclidean local…

  16. Embedded Spherical Localization for Micro Underwater Vehicles Based on Attenuation of Electro-Magnetic Carrier Signals

    PubMed Central

    Duecker, Daniel-André; Geist, A. René; Hengeler, Michael; Kreuzer, Edwin; Pick, Marc-André; Rausch, Viktor; Solowjow, Eugen

    2017-01-01

    Self-localization is one of the most challenging problems for deploying micro autonomous underwater vehicles (μAUV) in confined underwater environments. This paper extends a recently-developed self-localization method that is based on the attenuation of electro-magnetic waves, to the μAUV domain. We demonstrate a compact, low-cost architecture that is able to perform all signal processing steps present in the original method. The system is passive with one-way signal transmission and scales to possibly large μAUV fleets. It is based on the spherical localization concept. We present results from static and dynamic position estimation experiments and discuss the tradeoffs of the system. PMID:28445419

  17. Embedded Spherical Localization for Micro Underwater Vehicles Based on Attenuation of Electro-Magnetic Carrier Signals.

    PubMed

    Duecker, Daniel-André; Geist, A René; Hengeler, Michael; Kreuzer, Edwin; Pick, Marc-André; Rausch, Viktor; Solowjow, Eugen

    2017-04-26

    Self-localization is one of the most challenging problems for deploying micro autonomous underwater vehicles ( μ AUV) in confined underwater environments. This paper extends a recently-developed self-localization method that is based on the attenuation of electro-magnetic waves, to the μ AUV domain. We demonstrate a compact, low-cost architecture that is able to perform all signal processing steps present in the original method. The system is passive with one-way signal transmission and scales to possibly large μ AUV fleets. It is based on the spherical localization concept. We present results from static and dynamic position estimation experiments and discuss the tradeoffs of the system.

  18. Study on recent execution of overall evaluation bidding method in small and medium-sized regional local governments

    NASA Astrophysics Data System (ADS)

    Fujishima, Hirohide; Yanase, Norihiko

    About 70% of local governments in Japan, endeavored to introduce overall evaluation bidding method for their public works in 2011 and each authority ordered one or some projects in according to the new bidding process. That is, their enforcement was an only trial level and they say that the reason why is long-term procedure and heavily administrative load of the system. The author think that such burden has relationship of human affairs of local govern ments, practical problems on kinds and price of constructions and the officers' experience on the new bidding method. The aim of this study is to analyze such problems among the officers' profession, posts and experience of administrative matter by statistical data, questionnaire and hearing to the officers. The result could indicate that a group of small local governments uses the method appropriately and that another group of medium-sized rejects to increase more contracts in according to the new bidding system because of unbalance between the stuffs' ability and order quantity of public works.

  19. Measuring the local mobility of graphene on semiconductors

    NASA Astrophysics Data System (ADS)

    Zhong, Haijian; Liu, Zhenghui; Wang, Jianfeng; Pan, Anlian; Xu, Gengzhao; Xu, Ke

    2018-04-01

    Mobility is an important parameter to gauge the performance of graphene devices, which is usually measured by FET or Hall methods relying on the use of insulating substrates. However, these methods are not applicable for the case of graphene on semiconductors, because some current will inevitably cross their junctions and flow through the semiconductors except directly traversing the graphene surface. Here we demonstrate a method for measuring the local mobility of graphene on gallium nitrides combining Kelvin probe force microscopy (KPFM) and conductive atomic force microscopy (C-AFM). The carrier density related to Fermi level shifts in graphene can be acquired from KPFM. The local mobility of graphene is calculated from the carrier mean free path available from the effective contact area, which can be fitted from the local I-V curves in graphene/GaN junctions by C-AFM. Our method can be used to investigate an arbitrary region in graphene and also be applied to other semiconductor substrates and do not introduce damages. These results will benefit recent topical application researches for graphene integration in various semiconductor devices.

  20. Acoustic localization at large scales: a promising method for grey wolf monitoring.

    PubMed

    Papin, Morgane; Pichenot, Julian; Guérold, François; Germain, Estelle

    2018-01-01

    The grey wolf ( Canis lupus ) is naturally recolonizing its former habitats in Europe where it was extirpated during the previous two centuries. The management of this protected species is often controversial and its monitoring is a challenge for conservation purposes. However, this elusive carnivore can disperse over long distances in various natural contexts, making its monitoring difficult. Moreover, methods used for collecting signs of presence are usually time-consuming and/or costly. Currently, new acoustic recording tools are contributing to the development of passive acoustic methods as alternative approaches for detecting, monitoring, or identifying species that produce sounds in nature, such as the grey wolf. In the present study, we conducted field experiments to investigate the possibility of using a low-density microphone array to localize wolves at a large scale in two contrasting natural environments in north-eastern France. For scientific and social reasons, the experiments were based on a synthetic sound with similar acoustic properties to howls. This sound was broadcast at several sites. Then, localization estimates and the accuracy were calculated. Finally, linear mixed-effects models were used to identify the factors that influenced the localization accuracy. Among 354 nocturnal broadcasts in total, 269 were recorded by at least one autonomous recorder, thereby demonstrating the potential of this tool. Besides, 59 broadcasts were recorded by at least four microphones and used for acoustic localization. The broadcast sites were localized with an overall mean accuracy of 315 ± 617 (standard deviation) m. After setting a threshold for the temporal error value associated with the estimated coordinates, some unreliable values were excluded and the mean accuracy decreased to 167 ± 308 m. The number of broadcasts recorded was higher in the lowland environment, but the localization accuracy was similar in both environments, although it varied significantly among different nights in each study area. Our results confirm the potential of using acoustic methods to localize wolves with high accuracy, in different natural environments and at large spatial scales. Passive acoustic methods are suitable for monitoring the dynamics of grey wolf recolonization and so, will contribute to enhance conservation and management plans.

  1. Advances in local anesthesia in dentistry.

    PubMed

    Ogle, Orrett E; Mahjoubi, Ghazal

    2011-07-01

    Local pain management is the most critical aspect of patient care in dentistry. The improvements in agents and techniques for local anesthesia are probably the most significant advances that have occurred in dental science. This article provides an update on the most recently introduced local anesthetic agents along with new technologies used to deliver local anesthetics. Safety devices are also discussed, along with an innovative method for reducing the annoying numbness of the lip and tongue following local anesthesia. Copyright © 2011 Elsevier Inc. All rights reserved.

  2. Combining global and local approximations

    NASA Technical Reports Server (NTRS)

    Haftka, Raphael T.

    1991-01-01

    A method based on a linear approximation to a scaling factor, designated the 'global-local approximation' (GLA) method, is presented and shown capable of extending the range of usefulness of derivative-based approximations to a more refined model. The GLA approach refines the conventional scaling factor by means of a linearly varying, rather than constant, scaling factor. The capabilities of the method are demonstrated for a simple beam example with a crude and more refined FEM model.

  3. Hybridization of decomposition and local search for multiobjective optimization.

    PubMed

    Ke, Liangjun; Zhang, Qingfu; Battiti, Roberto

    2014-10-01

    Combining ideas from evolutionary algorithms, decomposition approaches, and Pareto local search, this paper suggests a simple yet efficient memetic algorithm for combinatorial multiobjective optimization problems: memetic algorithm based on decomposition (MOMAD). It decomposes a combinatorial multiobjective problem into a number of single objective optimization problems using an aggregation method. MOMAD evolves three populations: 1) population P(L) for recording the current solution to each subproblem; 2) population P(P) for storing starting solutions for Pareto local search; and 3) an external population P(E) for maintaining all the nondominated solutions found so far during the search. A problem-specific single objective heuristic can be applied to these subproblems to initialize the three populations. At each generation, a Pareto local search method is first applied to search a neighborhood of each solution in P(P) to update P(L) and P(E). Then a single objective local search is applied to each perturbed solution in P(L) for improving P(L) and P(E), and reinitializing P(P). The procedure is repeated until a stopping condition is met. MOMAD provides a generic hybrid multiobjective algorithmic framework in which problem specific knowledge, well developed single objective local search and heuristics and Pareto local search methods can be hybridized. It is a population based iterative method and thus an anytime algorithm. Extensive experiments have been conducted in this paper to study MOMAD and compare it with some other state-of-the-art algorithms on the multiobjective traveling salesman problem and the multiobjective knapsack problem. The experimental results show that our proposed algorithm outperforms or performs similarly to the best so far heuristics on these two problems.

  4. A method to characterize the roughness of 2-D line features: recrystallization boundaries.

    PubMed

    Sun, J; Zhang, Y B; Dahl, A B; Conradsen, K; Juul Jensen, D

    2017-03-01

    A method is presented, which allows quantification of the roughness of nonplanar boundaries of objects for which the neutral plane is not known. The method provides quantitative descriptions of both the local and global characteristics. How the method can be used to estimate the sizes of rough features and local curvatures is also presented. The potential of the method is illustrated by quantification of the roughness of two recrystallization boundaries in a pure Al specimen characterized by scanning electron microscopy. © 2016 The Authors Journal of Microscopy © 2016 Royal Microscopical Society.

  5. Atomistic cluster alignment method for local order mining in liquids and glasses

    NASA Astrophysics Data System (ADS)

    Fang, X. W.; Wang, C. Z.; Yao, Y. X.; Ding, Z. J.; Ho, K. M.

    2010-11-01

    An atomistic cluster alignment method is developed to identify and characterize the local atomic structural order in liquids and glasses. With the “order mining” idea for structurally disordered systems, the method can detect the presence of any type of local order in the system and can quantify the structural similarity between a given set of templates and the aligned clusters in a systematic and unbiased manner. Moreover, population analysis can also be carried out for various types of clusters in the system. The advantages of the method in comparison with other previously developed analysis methods are illustrated by performing the structural analysis for four prototype systems (i.e., pure Al, pure Zr, Zr35Cu65 , and Zr36Ni64 ). The results show that the cluster alignment method can identify various types of short-range orders (SROs) in these systems correctly while some of these SROs are difficult to capture by most of the currently available analysis methods (e.g., Voronoi tessellation method). Such a full three-dimensional atomistic analysis method is generic and can be applied to describe the magnitude and nature of noncrystalline ordering in many disordered systems.

  6. A portable mid-range localization system using infrared LEDs for visually impaired people

    NASA Astrophysics Data System (ADS)

    Park, Suhyeon; Choi, In-Mook; Kim, Sang-Soo; Kim, Sung-Mok

    2014-11-01

    A versatile indoor/outdoor pedestrian guidance system with good mobility is necessary in order to aid visually impaired pedestrians in indoor and outdoor environments. In this paper, distance estimation methods for portable wireless localization systems are verified. Two systems of a fixed active beacon and a receiver using an ultrasound time-of-flight method and a differential infrared intensity method are proposed. The infrared localization system was appropriate for the goal of this study. It was possible to use the infrared intensity method to generate a uniform signal field that exceeded 30 m. Valid distance estimations which were within 30 m of coverage indoors and within 20 m of coverage outdoors were made. Also, a pocket-sized receiver which can be adapted to a smartphone was found to be suitable for use as a portable device.

  7. Finite-analytic numerical solution of heat transfer in two-dimensional cavity flow

    NASA Technical Reports Server (NTRS)

    Chen, C.-J.; Naseri-Neshat, H.; Ho, K.-S.

    1981-01-01

    Heat transfer in cavity flow is numerically analyzed by a new numerical method called the finite-analytic method. The basic idea of the finite-analytic method is the incorporation of local analytic solutions in the numerical solutions of linear or nonlinear partial differential equations. In the present investigation, the local analytic solutions for temperature, stream function, and vorticity distributions are derived. When the local analytic solution is evaluated at a given nodal point, it gives an algebraic relationship between a nodal value in a subregion and its neighboring nodal points. A system of algebraic equations is solved to provide the numerical solution of the problem. The finite-analytic method is used to solve heat transfer in the cavity flow at high Reynolds number (1000) for Prandtl numbers of 0.1, 1, and 10.

  8. Tempest - Efficient Computation of Atmospheric Flows Using High-Order Local Discretization Methods

    NASA Astrophysics Data System (ADS)

    Ullrich, P. A.; Guerra, J. E.

    2014-12-01

    The Tempest Framework composes several compact numerical methods to easily facilitate intercomparison of atmospheric flow calculations on the sphere and in rectangular domains. This framework includes the implementations of Spectral Elements, Discontinuous Galerkin, Flux Reconstruction, and Hybrid Finite Element methods with the goal of achieving optimal accuracy in the solution of atmospheric problems. Several advantages of this approach are discussed such as: improved pressure gradient calculation, numerical stability by vertical/horizontal splitting, arbitrary order of accuracy, etc. The local numerical discretization allows for high performance parallel computation and efficient inclusion of parameterizations. These techniques are used in conjunction with a non-conformal, locally refined, cubed-sphere grid for global simulations and standard Cartesian grids for simulations at the mesoscale. A complete implementation of the methods described is demonstrated in a non-hydrostatic setting.

  9. Beam shape coefficients calculation for an elliptical Gaussian beam with 1-dimensional quadrature and localized approximation methods

    NASA Astrophysics Data System (ADS)

    Wang, Wei; Shen, Jianqi

    2018-06-01

    The use of a shaped beam for applications relying on light scattering depends much on the ability to evaluate the beam shape coefficients (BSC) effectively. Numerical techniques for evaluating the BSCs of a shaped beam, such as the quadrature, the localized approximation (LA), the integral localized approximation (ILA) methods, have been developed within the framework of generalized Lorenz-Mie theory (GLMT). The quadrature methods usually employ the 2-/3-dimensional integrations. In this work, the expressions of the BSCs for an elliptical Gaussian beam (EGB) are simplified into the 1-dimensional integral so as to speed up the numerical computation. Numerical results of BSCs are used to reconstruct the beam field and the fidelity of the reconstructed field to the given beam field is estimated. It is demonstrated that the proposed method is much faster than the 2-dimensional integrations and it can acquire more accurate results than the LA method. Limitations of the quadrature method and also the LA method in the numerical calculation are analyzed in detail.

  10. A high-order staggered meshless method for elliptic problems

    DOE PAGES

    Trask, Nathaniel; Perego, Mauro; Bochev, Pavel Blagoveston

    2017-03-21

    Here, we present a new meshless method for scalar diffusion equations, which is motivated by their compatible discretizations on primal-dual grids. Unlike the latter though, our approach is truly meshless because it only requires the graph of nearby neighbor connectivity of the discretization points. This graph defines a local primal-dual grid complex with a virtual dual grid, in the sense that specification of the dual metric attributes is implicit in the method's construction. Our method combines a topological gradient operator on the local primal grid with a generalized moving least squares approximation of the divergence on the local dual grid. We show that the resulting approximation of the div-grad operator maintains polynomial reproduction to arbitrary orders and yields a meshless method, which attainsmore » $$O(h^{m})$$ convergence in both $L^2$- and $H^1$-norms, similar to mixed finite element methods. We demonstrate this convergence on curvilinear domains using manufactured solutions in two and three dimensions. Application of the new method to problems with discontinuous coefficients reveals solutions that are qualitatively similar to those of compatible mesh-based discretizations.« less

  11. A hybrid localization technique for patient tracking.

    PubMed

    Rodionov, Denis; Kolev, George; Bushminkin, Kirill

    2013-01-01

    Nowadays numerous technologies are employed for tracking patients and assets in hospitals or nursing homes. Each of them has advantages and drawbacks. For example, WiFi localization has relatively good accuracy but cannot be used in case of power outage or in the areas with poor WiFi coverage. Magnetometer positioning or cellular network does not have such problems but they are not as accurate as localization with WiFi. This paper describes technique that simultaneously employs different localization technologies for enhancing stability and average accuracy of localization. The proposed algorithm is based on fingerprinting method paired with data fusion and prediction algorithms for estimating the object location. The core idea of the algorithm is technology fusion using error estimation methods. For testing accuracy and performance of the algorithm testing simulation environment has been implemented. Significant accuracy improvement was showed in practical scenarios.

  12. Local polynomial estimation of heteroscedasticity in a multivariate linear regression model and its applications in economics.

    PubMed

    Su, Liyun; Zhao, Yanyong; Yan, Tianshun; Li, Fenglan

    2012-01-01

    Multivariate local polynomial fitting is applied to the multivariate linear heteroscedastic regression model. Firstly, the local polynomial fitting is applied to estimate heteroscedastic function, then the coefficients of regression model are obtained by using generalized least squares method. One noteworthy feature of our approach is that we avoid the testing for heteroscedasticity by improving the traditional two-stage method. Due to non-parametric technique of local polynomial estimation, it is unnecessary to know the form of heteroscedastic function. Therefore, we can improve the estimation precision, when the heteroscedastic function is unknown. Furthermore, we verify that the regression coefficients is asymptotic normal based on numerical simulations and normal Q-Q plots of residuals. Finally, the simulation results and the local polynomial estimation of real data indicate that our approach is surely effective in finite-sample situations.

  13. Iterative refinement of implicit boundary models for improved geological feature reproduction

    NASA Astrophysics Data System (ADS)

    Martin, Ryan; Boisvert, Jeff B.

    2017-12-01

    Geological domains contain non-stationary features that cannot be described by a single direction of continuity. Non-stationary estimation frameworks generate more realistic curvilinear interpretations of subsurface geometries. A radial basis function (RBF) based implicit modeling framework using domain decomposition is developed that permits introduction of locally varying orientations and magnitudes of anisotropy for boundary models to better account for the local variability of complex geological deposits. The interpolation framework is paired with a method to automatically infer the locally predominant orientations, which results in a rapid and robust iterative non-stationary boundary modeling technique that can refine locally anisotropic geological shapes automatically from the sample data. The method also permits quantification of the volumetric uncertainty associated with the boundary modeling. The methodology is demonstrated on a porphyry dataset and shows improved local geological features.

  14. Nonlinear structural joint model updating based on instantaneous characteristics of dynamic responses

    NASA Astrophysics Data System (ADS)

    Wang, Zuo-Cai; Xin, Yu; Ren, Wei-Xin

    2016-08-01

    This paper proposes a new nonlinear joint model updating method for shear type structures based on the instantaneous characteristics of the decomposed structural dynamic responses. To obtain an accurate representation of a nonlinear system's dynamics, the nonlinear joint model is described as the nonlinear spring element with bilinear stiffness. The instantaneous frequencies and amplitudes of the decomposed mono-component are first extracted by the analytical mode decomposition (AMD) method. Then, an objective function based on the residuals of the instantaneous frequencies and amplitudes between the experimental structure and the nonlinear model is created for the nonlinear joint model updating. The optimal values of the nonlinear joint model parameters are obtained by minimizing the objective function using the simulated annealing global optimization method. To validate the effectiveness of the proposed method, a single-story shear type structure subjected to earthquake and harmonic excitations is simulated as a numerical example. Then, a beam structure with multiple local nonlinear elements subjected to earthquake excitation is also simulated. The nonlinear beam structure is updated based on the global and local model using the proposed method. The results show that the proposed local nonlinear model updating method is more effective for structures with multiple local nonlinear elements. Finally, the proposed method is verified by the shake table test of a real high voltage switch structure. The accuracy of the proposed method is quantified both in numerical and experimental applications using the defined error indices. Both the numerical and experimental results have shown that the proposed method can effectively update the nonlinear joint model.

  15. A locally adaptive kernel regression method for facies delineation

    NASA Astrophysics Data System (ADS)

    Fernàndez-Garcia, D.; Barahona-Palomo, M.; Henri, C. V.; Sanchez-Vila, X.

    2015-12-01

    Facies delineation is defined as the separation of geological units with distinct intrinsic characteristics (grain size, hydraulic conductivity, mineralogical composition). A major challenge in this area stems from the fact that only a few scattered pieces of hydrogeological information are available to delineate geological facies. Several methods to delineate facies are available in the literature, ranging from those based only on existing hard data, to those including secondary data or external knowledge about sedimentological patterns. This paper describes a methodology to use kernel regression methods as an effective tool for facies delineation. The method uses both the spatial and the actual sampled values to produce, for each individual hard data point, a locally adaptive steering kernel function, self-adjusting the principal directions of the local anisotropic kernels to the direction of highest local spatial correlation. The method is shown to outperform the nearest neighbor classification method in a number of synthetic aquifers whenever the available number of hard data is small and randomly distributed in space. In the case of exhaustive sampling, the steering kernel regression method converges to the true solution. Simulations ran in a suite of synthetic examples are used to explore the selection of kernel parameters in typical field settings. It is shown that, in practice, a rule of thumb can be used to obtain suboptimal results. The performance of the method is demonstrated to significantly improve when external information regarding facies proportions is incorporated. Remarkably, the method allows for a reasonable reconstruction of the facies connectivity patterns, shown in terms of breakthrough curves performance.

  16. A Self-Adaptive Model-Based Wi-Fi Indoor Localization Method.

    PubMed

    Tuta, Jure; Juric, Matjaz B

    2016-12-06

    This paper presents a novel method for indoor localization, developed with the main aim of making it useful for real-world deployments. Many indoor localization methods exist, yet they have several disadvantages in real-world deployments-some are static, which is not suitable for long-term usage; some require costly human recalibration procedures; and others require special hardware such as Wi-Fi anchors and transponders. Our method is self-calibrating and self-adaptive thus maintenance free and based on Wi-Fi only. We have employed two well-known propagation models-free space path loss and ITU models-which we have extended with additional parameters for better propagation simulation. Our self-calibrating procedure utilizes one propagation model to infer parameters of the space and the other to simulate the propagation of the signal without requiring any additional hardware beside Wi-Fi access points, which is suitable for real-world usage. Our method is also one of the few model-based Wi-Fi only self-adaptive approaches that do not require the mobile terminal to be in the access-point mode. The only input requirements of the method are Wi-Fi access point positions, and positions and properties of the walls. Our method has been evaluated in single- and multi-room environments, with measured mean error of 2-3 and 3-4 m, respectively, which is similar to existing methods. The evaluation has proven that usable localization accuracy can be achieved in real-world environments solely by the proposed Wi-Fi method that relies on simple hardware and software requirements.

  17. A Self-Adaptive Model-Based Wi-Fi Indoor Localization Method

    PubMed Central

    Tuta, Jure; Juric, Matjaz B.

    2016-01-01

    This paper presents a novel method for indoor localization, developed with the main aim of making it useful for real-world deployments. Many indoor localization methods exist, yet they have several disadvantages in real-world deployments—some are static, which is not suitable for long-term usage; some require costly human recalibration procedures; and others require special hardware such as Wi-Fi anchors and transponders. Our method is self-calibrating and self-adaptive thus maintenance free and based on Wi-Fi only. We have employed two well-known propagation models—free space path loss and ITU models—which we have extended with additional parameters for better propagation simulation. Our self-calibrating procedure utilizes one propagation model to infer parameters of the space and the other to simulate the propagation of the signal without requiring any additional hardware beside Wi-Fi access points, which is suitable for real-world usage. Our method is also one of the few model-based Wi-Fi only self-adaptive approaches that do not require the mobile terminal to be in the access-point mode. The only input requirements of the method are Wi-Fi access point positions, and positions and properties of the walls. Our method has been evaluated in single- and multi-room environments, with measured mean error of 2–3 and 3–4 m, respectively, which is similar to existing methods. The evaluation has proven that usable localization accuracy can be achieved in real-world environments solely by the proposed Wi-Fi method that relies on simple hardware and software requirements. PMID:27929453

  18. Three-dimensional local grid refinement for block-centered finite-difference groundwater models using iteratively coupled shared nodes: A new method of interpolation and analysis of errors

    USGS Publications Warehouse

    Mehl, S.; Hill, M.C.

    2004-01-01

    This paper describes work that extends to three dimensions the two-dimensional local-grid refinement method for block-centered finite-difference groundwater models of Mehl and Hill [Development and evaluation of a local grid refinement method for block-centered finite-difference groundwater models using shared nodes. Adv Water Resour 2002;25(5):497-511]. In this approach, the (parent) finite-difference grid is discretized more finely within a (child) sub-region. The grid refinement method sequentially solves each grid and uses specified flux (parent) and specified head (child) boundary conditions to couple the grids. Iteration achieves convergence between heads and fluxes of both grids. Of most concern is how to interpolate heads onto the boundary of the child grid such that the physics of the parent-grid flow is retained in three dimensions. We develop a new two-step, "cage-shell" interpolation method based on the solution of the flow equation on the boundary of the child between nodes shared with the parent grid. Error analysis using a test case indicates that the shared-node local grid refinement method with cage-shell boundary head interpolation is accurate and robust, and the resulting code is used to investigate three-dimensional local grid refinement of stream-aquifer interactions. Results reveal that (1) the parent and child grids interact to shift the true head and flux solution to a different solution where the heads and fluxes of both grids are in equilibrium, (2) the locally refined model provided a solution for both heads and fluxes in the region of the refinement that was more accurate than a model without refinement only if iterations are performed so that both heads and fluxes are in equilibrium, and (3) the accuracy of the coupling is limited by the parent-grid size - A coarse parent grid limits correct representation of the hydraulics in the feedback from the child grid.

  19. Combining local scaling and global methods to detect soil pore space

    NASA Astrophysics Data System (ADS)

    Martin-Sotoca, Juan Jose; Saa-Requejo, Antonio; Grau, Juan B.; Tarquis, Ana M.

    2017-04-01

    The characterization of the spatial distribution of soil pore structures is essential to obtain different parameters that will influence in several models related to water flow and/or microbial growth processes. The first step in pore structure characterization is obtaining soil images that best approximate reality. Over the last decade, major technological advances in X-ray computed tomography (CT) have allowed for the investigation and reconstruction of natural porous media architectures at very fine scales. The subsequent step is delimiting the pore structure (pore space) from the CT soil images applying a thresholding. Many times we could find CT-scan images that show low contrast at the solid-void interface that difficult this step. Different delimitation methods can result in different spatial distributions of pores influencing the parameters used in the models. Recently, new local segmentation method using local greyscale value (GV) concentration variabilities, based on fractal concepts, has been presented. This method creates singularity maps to measure the GV concentration at each point. The C-A method was combined with the singularity map approach (Singularity-CA method) to define local thresholds that can be applied to binarize CT images. Comparing this method with classical methods, such as Otsu and Maximum Entropy, we observed that more pores can be detected mainly due to its ability to amplify anomalous concentrations. However, it delineated many small pores that were incorrect. In this work, we present an improve version of Singularity-CA method that avoid this problem basically combining it with the global classical methods. References Martín-Sotoca, J.J., A. Saa-Requejo, J.B. Grau, A.M. Tarquis. New segmentation method based on fractal properties using singularity maps. Geoderma, 287, 40-53, 2017. Martín-Sotoca, J.J, A. Saa-Requejo, J.B. Grau, A.M. Tarquis. Local 3D segmentation of soil pore space based on fractal properties using singularity maps. Geoderma, http://dx.doi.org/10.1016/j.geoderma.2016.11.029. Torre, Iván G., Juan C. Losada and A.M. Tarquis. Multiscaling properties of soil images. Biosystems Engineering, http://dx.doi.org/10.1016/j.biosystemseng.2016.11.006.

  20. Multi-resolution analysis using integrated microscopic configuration with local patterns for benign-malignant mass classification

    NASA Astrophysics Data System (ADS)

    Rabidas, Rinku; Midya, Abhishek; Chakraborty, Jayasree; Sadhu, Anup; Arif, Wasim

    2018-02-01

    In this paper, Curvelet based local attributes, Curvelet-Local configuration pattern (C-LCP), is introduced for the characterization of mammographic masses as benign or malignant. Amid different anomalies such as micro- calcification, bilateral asymmetry, architectural distortion, and masses, the reason for targeting the mass lesions is due to their variation in shape, size, and margin which makes the diagnosis a challenging task. Being efficient in classification, multi-resolution property of the Curvelet transform is exploited and local information is extracted from the coefficients of each subband using Local configuration pattern (LCP). The microscopic measures in concatenation with the local textural information provide more discriminating capability than individual. The measures embody the magnitude information along with the pixel-wise relationships among the neighboring pixels. The performance analysis is conducted with 200 mammograms of the DDSM database containing 100 mass cases of each benign and malignant. The optimal set of features is acquired via stepwise logistic regression method and the classification is carried out with Fisher linear discriminant analysis. The best area under the receiver operating characteristic curve and accuracy of 0.95 and 87.55% are achieved with the proposed method, which is further compared with some of the state-of-the-art competing methods.

  1. Parallel magnetic resonance imaging using coils with localized sensitivities.

    PubMed

    Goldfarb, James W; Holland, Agnes E

    2004-09-01

    The purpose of this study was to present clinical examples and illustrate the inefficiencies of a conventional reconstruction using a commercially available phased array coil with localized sensitivities. Five patients were imaged at 1.5 T using a cardiac-synchronized gadolinium-enhanced acquisition and a commercially available four-element phased array coil. Four unique sets of images were reconstructed from the acquired k-space data: (a) sum-of-squares image using four elements of the coil; localized sum-of-squares images from the (b) anterior coils and (c) posterior coils and a (c) local reconstruction. Images were analyzed for artifacts and usable field-of-view. Conventional image reconstruction produced images with fold-over artifacts in all cases spanning a portion of the image (mean 90 mm; range 36-126 mm). The local reconstruction removed fold-over artifacts and resulted in an effective increase in the field-of-view (mean 50%; range 20-70%). Commercially available phased array coils do not always have overlapping sensitivities. Fold-over artifacts can be removed using an alternate reconstruction method. When assessing the advantages of parallel imaging techniques, gains achieved using techniques such as SENSE and SMASH should be gauged against the acquisition time of the localized method rather than the conventional sum-of-squares method.

  2. Effects of reconstructed magnetic field from sparse noisy boundary measurements on localization of active neural source.

    PubMed

    Shen, Hui-min; Lee, Kok-Meng; Hu, Liang; Foong, Shaohui; Fu, Xin

    2016-01-01

    Localization of active neural source (ANS) from measurements on head surface is vital in magnetoencephalography. As neuron-generated magnetic fields are extremely weak, significant uncertainties caused by stochastic measurement interference complicate its localization. This paper presents a novel computational method based on reconstructed magnetic field from sparse noisy measurements for enhanced ANS localization by suppressing effects of unrelated noise. In this approach, the magnetic flux density (MFD) in the nearby current-free space outside the head is reconstructed from measurements through formulating the infinite series solution of the Laplace's equation, where boundary condition (BC) integrals over the entire measurements provide "smooth" reconstructed MFD with the decrease in unrelated noise. Using a gradient-based method, reconstructed MFDs with good fidelity are selected for enhanced ANS localization. The reconstruction model, spatial interpolation of BC, parametric equivalent current dipole-based inverse estimation algorithm using reconstruction, and gradient-based selection are detailed and validated. The influences of various source depths and measurement signal-to-noise ratio levels on the estimated ANS location are analyzed numerically and compared with a traditional method (where measurements are directly used), and it was demonstrated that gradient-selected high-fidelity reconstructed data can effectively improve the accuracy of ANS localization.

  3. Localization of phonons in mass-disordered alloys: A typical medium dynamical cluster approach

    DOE PAGES

    Jarrell, Mark; Moreno, Juana; Raja Mondal, Wasim; ...

    2017-07-20

    The effect of disorder on lattice vibrational modes has been a topic of interest for several decades. In this article, we employ a Green's function based approach, namely, the dynamical cluster approximation (DCA), to investigate phonons in mass-disordered systems. Detailed benchmarks with previous exact calculations are used to validate the method in a wide parameter space. An extension of the method, namely, the typical medium DCA (TMDCA), is used to study Anderson localization of phonons in three dimensions. We show that, for binary isotopic disorder, lighter impurities induce localized modes beyond the bandwidth of the host system, while heavier impuritiesmore » lead to a partial localization of the low-frequency acoustic modes. For a uniform (box) distribution of masses, the physical spectrum is shown to develop long tails comprising mostly localized modes. The mobility edge separating extended and localized modes, obtained through the TMDCA, agrees well with results from the transfer matrix method. A reentrance behavior of the mobility edge with increasing disorder is found that is similar to, but somewhat more pronounced than, the behavior in disordered electronic systems. Our work establishes a computational approach, which recovers the thermodynamic limit, is versatile and computationally inexpensive, to investigate lattice vibrations in disordered lattice systems.« less

  4. Distribution of localized states from fine analysis of electron spin resonance spectra of organic semiconductors: Physical meaning and methodology

    NASA Astrophysics Data System (ADS)

    Mishchenko, Andrey S.; Matsui, Hiroyuki; Hasegawa, Tatsuo

    2012-02-01

    We develop an analytical method for the processing of electron spin resonance (ESR) spectra. The goal is to obtain the distributions of trapped carriers over both their degree of localization and their binding energy in semiconductor crystals or films composed of regularly aligned organic molecules [Phys. Rev. Lett.PRLTAO0031-900710.1103/PhysRevLett.104.056602 104, 056602 (2010)]. Our method has two steps. We first carry out a fine analysis of the shape of the ESR spectra due to the trapped carriers; this reveals the distribution of the trap density of the states over the degree of localization. This analysis is based on the reasonable assumption that the linewidth of the trapped carriers is predetermined by their degree of localization because of the hyperfine mechanism. We then transform the distribution over the degree of localization into a distribution over the binding energies. The transformation uses the relationships between the binding energies and the localization parameters of the trapped carriers. The particular relation for the system under study is obtained by the Holstein model for trapped polarons using a diagrammatic Monte Carlo analysis. We illustrate the application of the method to pentacene organic thin-film transistors.

  5. Localization of phonons in mass-disordered alloys: A typical medium dynamical cluster approach

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jarrell, Mark; Moreno, Juana; Raja Mondal, Wasim

    The effect of disorder on lattice vibrational modes has been a topic of interest for several decades. In this article, we employ a Green's function based approach, namely, the dynamical cluster approximation (DCA), to investigate phonons in mass-disordered systems. Detailed benchmarks with previous exact calculations are used to validate the method in a wide parameter space. An extension of the method, namely, the typical medium DCA (TMDCA), is used to study Anderson localization of phonons in three dimensions. We show that, for binary isotopic disorder, lighter impurities induce localized modes beyond the bandwidth of the host system, while heavier impuritiesmore » lead to a partial localization of the low-frequency acoustic modes. For a uniform (box) distribution of masses, the physical spectrum is shown to develop long tails comprising mostly localized modes. The mobility edge separating extended and localized modes, obtained through the TMDCA, agrees well with results from the transfer matrix method. A reentrance behavior of the mobility edge with increasing disorder is found that is similar to, but somewhat more pronounced than, the behavior in disordered electronic systems. Our work establishes a computational approach, which recovers the thermodynamic limit, is versatile and computationally inexpensive, to investigate lattice vibrations in disordered lattice systems.« less

  6. On the Local Convergence of Pattern Search

    NASA Technical Reports Server (NTRS)

    Dolan, Elizabeth D.; Lewis, Robert Michael; Torczon, Virginia; Bushnell, Dennis M. (Technical Monitor)

    2000-01-01

    We examine the local convergence properties of pattern search methods, complementing the previously established global convergence properties for this class of algorithms. We show that the step-length control parameter which appears in the definition of pattern search algorithms provides a reliable asymptotic measure of first-order stationarity. This gives an analytical justification for a traditional stopping criterion for pattern search methods. Using this measure of first-order stationarity, we analyze the behavior of pattern search in the neighborhood of an isolated local minimizer. We show that a recognizable subsequence converges r-linearly to the minimizer.

  7. Nonparametric method for failures detection and localization in the actuating subsystem of aircraft control system

    NASA Astrophysics Data System (ADS)

    Karpenko, S. S.; Zybin, E. Yu; Kosyanchuk, V. V.

    2018-02-01

    In this paper we design a nonparametric method for failures detection and localization in the aircraft control system that uses the measurements of the control signals and the aircraft states only. It doesn’t require a priori information of the aircraft model parameters, training or statistical calculations, and is based on algebraic solvability conditions for the aircraft model identification problem. This makes it possible to significantly increase the efficiency of detection and localization problem solution by completely eliminating errors, associated with aircraft model uncertainties.

  8. Towards local progression estimation of pulmonary emphysema using CT.

    PubMed

    Staring, M; Bakker, M E; Stolk, J; Shamonin, D P; Reiber, J H C; Stoel, B C

    2014-02-01

    Whole lung densitometry on chest CT images is an accepted method for measuring tissue destruction in patients with pulmonary emphysema in clinical trials. Progression measurement is required for evaluation of change in health condition and the effect of drug treatment. Information about the location of emphysema progression within the lung may be important for the correct interpretation of drug efficacy, or for determining a treatment plan. The purpose of this study is therefore to develop and validate methods that enable the local measurement of lung density changes, which requires proper modeling of the effect of respiration on density. Four methods, all based on registration of baseline and follow-up chest CT scans, are compared. The first naïve method subtracts registered images. The second employs the so-called dry sponge model, where volume correction is performed using the determinant of the Jacobian of the transformation. The third and the fourth introduce a novel adaptation of the dry sponge model that circumvents its constant-mass assumption, which is shown to be invalid. The latter two methods require a third CT scan at a different inspiration level to estimate the patient-specific density-volume slope, where one method employs a global and the other a local slope. The methods were validated on CT scans of a phantom mimicking the lung, where mass and volume could be controlled. In addition, validation was performed on data of 21 patients with pulmonary emphysema. The image registration method was optimized leaving a registration error below half the slice increment (median 1.0 mm). The phantom study showed that the locally adapted slope model most accurately measured local progression. The systematic error in estimating progression, as measured on the phantom data, was below 2 gr/l for a 70 ml (6%) volume difference, and 5 gr/l for a 210 ml (19%) difference, if volume correction was applied. On the patient data an underlying linearity assumption relating lung volume change with density change was shown to hold (fitR(2) = 0.94), and globalized versions of the local models are consistent with global results (R(2) of 0.865 and 0.882 for the two adapted slope models, respectively). In conclusion, image matching and subsequent analysis of differences according to the proposed lung models (i) has good local registration accuracy on patient data, (ii) effectively eliminates a dependency on inspiration level at acquisition time, (iii) accurately predicts progression in phantom data, and (iv) is reasonably consistent with global results in patient data. It is therefore a potential future tool for assessing local emphysema progression in drug evaluation trials and in clinical practice.

  9. Optic disk localization by a robust fusion method

    NASA Astrophysics Data System (ADS)

    Zhang, Jielin; Yin, Fengshou; Wong, Damon W. K.; Liu, Jiang; Baskaran, Mani; Cheng, Ching-Yu; Wong, Tien Yin

    2013-02-01

    The optic disk localization plays an important role in developing computer-aided diagnosis (CAD) systems for ocular diseases such as glaucoma, diabetic retinopathy and age-related macula degeneration. In this paper, we propose an intelligent fusion of methods for the localization of the optic disk in retinal fundus images. Three different approaches are developed to detect the location of the optic disk separately. The first method is the maximum vessel crossing method, which finds the region with the most number of blood vessel crossing points. The second one is the multichannel thresholding method, targeting the area with the highest intensity. The final method searches the vertical and horizontal region-of-interest separately on the basis of blood vessel structure and neighborhood entropy profile. Finally, these three methods are combined using an intelligent fusion method to improve the overall accuracy. The proposed algorithm was tested on the STARE database and the ORIGAlight database, each consisting of images with various pathologies. The preliminary result on the STARE database can achieve 81.5%, while a higher result of 99% can be obtained for the ORIGAlight database. The proposed method outperforms each individual approach and state-of-the-art method which utilizes an intensity-based approach. The result demonstrates a high potential for this method to be used in retinal CAD systems.

  10. Application of empirical mode decomposition with local linear quantile regression in financial time series forecasting.

    PubMed

    Jaber, Abobaker M; Ismail, Mohd Tahir; Altaher, Alsaidi M

    2014-01-01

    This paper mainly forecasts the daily closing price of stock markets. We propose a two-stage technique that combines the empirical mode decomposition (EMD) with nonparametric methods of local linear quantile (LLQ). We use the proposed technique, EMD-LLQ, to forecast two stock index time series. Detailed experiments are implemented for the proposed method, in which EMD-LPQ, EMD, and Holt-Winter methods are compared. The proposed EMD-LPQ model is determined to be superior to the EMD and Holt-Winter methods in predicting the stock closing prices.

  11. A symmetric Trefftz-DG formulation based on a local boundary element method for the solution of the Helmholtz equation

    NASA Astrophysics Data System (ADS)

    Barucq, H.; Bendali, A.; Fares, M.; Mattesi, V.; Tordeux, S.

    2017-02-01

    A general symmetric Trefftz Discontinuous Galerkin method is built for solving the Helmholtz equation with piecewise constant coefficients. The construction of the corresponding local solutions to the Helmholtz equation is based on a boundary element method. A series of numerical experiments displays an excellent stability of the method relatively to the penalty parameters, and more importantly its outstanding ability to reduce the instabilities known as the "pollution effect" in the literature on numerical simulations of long-range wave propagation.

  12. Integrated Detection and Prediction of Influenza Activity for Real-Time Surveillance: Algorithm Design.

    PubMed

    Spreco, Armin; Eriksson, Olle; Dahlström, Örjan; Cowling, Benjamin John; Timpka, Toomas

    2017-06-15

    Influenza is a viral respiratory disease capable of causing epidemics that represent a threat to communities worldwide. The rapidly growing availability of electronic "big data" from diagnostic and prediagnostic sources in health care and public health settings permits advance of a new generation of methods for local detection and prediction of winter influenza seasons and influenza pandemics. The aim of this study was to present a method for integrated detection and prediction of influenza virus activity in local settings using electronically available surveillance data and to evaluate its performance by retrospective application on authentic data from a Swedish county. An integrated detection and prediction method was formally defined based on a design rationale for influenza detection and prediction methods adapted for local surveillance. The novel method was retrospectively applied on data from the winter influenza season 2008-09 in a Swedish county (population 445,000). Outcome data represented individuals who met a clinical case definition for influenza (based on International Classification of Diseases version 10 [ICD-10] codes) from an electronic health data repository. Information from calls to a telenursing service in the county was used as syndromic data source. The novel integrated detection and prediction method is based on nonmechanistic statistical models and is designed for integration in local health information systems. The method is divided into separate modules for detection and prediction of local influenza virus activity. The function of the detection module is to alert for an upcoming period of increased load of influenza cases on local health care (using influenza-diagnosis data), whereas the function of the prediction module is to predict the timing of the activity peak (using syndromic data) and its intensity (using influenza-diagnosis data). For detection modeling, exponential regression was used based on the assumption that the beginning of a winter influenza season has an exponential growth of infected individuals. For prediction modeling, linear regression was applied on 7-day periods at the time in order to find the peak timing, whereas a derivate of a normal distribution density function was used to find the peak intensity. We found that the integrated detection and prediction method detected the 2008-09 winter influenza season on its starting day (optimal timeliness 0 days), whereas the predicted peak was estimated to occur 7 days ahead of the factual peak and the predicted peak intensity was estimated to be 26% lower than the factual intensity (6.3 compared with 8.5 influenza-diagnosis cases/100,000). Our detection and prediction method is one of the first integrated methods specifically designed for local application on influenza data electronically available for surveillance. The performance of the method in a retrospective study indicates that further prospective evaluations of the methods are justified. ©Armin Spreco, Olle Eriksson, Örjan Dahlström, Benjamin John Cowling, Toomas Timpka. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 15.06.2017.

  13. 34 CFR Appendix to Subpart K of... - Determinations Under Section 8009 of the Act-Methods of Calculations for Treatment of Impact Aid...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... received from local non-tax sources such as interest, bake sales, gifts, donations, and in-kind... pupil from local interest, bake sales, in-kind contributions, and other non-tax local sources. The... ($700/$700). The local revenue received from interest, bake sales, in-kind contributions and other non...

  14. 34 CFR Appendix to Subpart K of... - Determinations Under Section 8009 of the Act-Methods of Calculations for Treatment of Impact Aid...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... received from local non-tax sources such as interest, bake sales, gifts, donations, and in-kind... pupil from local interest, bake sales, in-kind contributions, and other non-tax local sources. The... ($700/$700). The local revenue received from interest, bake sales, in-kind contributions and other non...

  15. 34 CFR Appendix to Subpart K of... - Determinations Under Section 8009 of the Act-Methods of Calculations for Treatment of Impact Aid...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... received from local non-tax sources such as interest, bake sales, gifts, donations, and in-kind... pupil from local interest, bake sales, in-kind contributions, and other non-tax local sources. The... ($700/$700). The local revenue received from interest, bake sales, in-kind contributions and other non...

  16. 34 CFR Appendix to Subpart K of... - Determinations Under Section 8009 of the Act-Methods of Calculations for Treatment of Impact Aid...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... received from local non-tax sources such as interest, bake sales, gifts, donations, and in-kind... pupil from local interest, bake sales, in-kind contributions, and other non-tax local sources. The... ($700/$700). The local revenue received from interest, bake sales, in-kind contributions and other non...

  17. 34 CFR Appendix to Subpart K of... - Determinations Under Section 8009 of the Act-Methods of Calculations for Treatment of Impact Aid...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... received from local non-tax sources such as interest, bake sales, gifts, donations, and in-kind... pupil from local interest, bake sales, in-kind contributions, and other non-tax local sources. The... ($700/$700). The local revenue received from interest, bake sales, in-kind contributions and other non...

  18. Galaxy clusters in local Universe simulations without density constraints: a long uphill struggle

    NASA Astrophysics Data System (ADS)

    Sorce, Jenny G.

    2018-06-01

    Galaxy clusters are excellent cosmological probes provided that their formation and evolution within the large scale environment are precisely understood. Therefore studies with simulated galaxy clusters have flourished. However detailed comparisons between simulated and observed clusters and their population - the galaxies - are complicated by the diversity of clusters and their surrounding environment. An original way initiated by Bertschinger as early as 1987, to legitimize the one-to-one comparison exercise down to the details, is to produce simulations constrained to resemble the cluster under study within its large scale environment. Subsequently several methods have emerged to produce simulations that look like the local Universe. This paper highlights one of these methods and its essential steps to get simulations that not only resemble the local Large Scale Structure but also that host the local clusters. It includes a new modeling of the radial peculiar velocity uncertainties to remove the observed correlation between the decreases of the simulated cluster masses and of the amount of data used as constraints with the distance from us. This method has the particularity to use solely radial peculiar velocities as constraints: no additional density constraints are required to get local cluster simulacra. The new resulting simulations host dark matter halos that match the most prominent local clusters such as Coma. Zoom-in simulations of the latter and of a volume larger than the 30h-1 Mpc radius inner sphere become now possible to study local clusters and their effects. Mapping the local Sunyaev-Zel'dovich and Sachs-Wolfe effects can follow.

  19. Estimating Local Chlamydia Incidence and Prevalence Using Surveillance Data

    PubMed Central

    White, Peter J.

    2017-01-01

    Background: Understanding patterns of chlamydia prevalence is important for addressing inequalities and planning cost-effective control programs. Population-based surveys are costly; the best data for England come from the Natsal national surveys, which are only available once per decade, and are nationally representative but not powered to compare prevalence in different localities. Prevalence estimates at finer spatial and temporal scales are required. Methods: We present a method for estimating local prevalence by modeling the infection, testing, and treatment processes. Prior probability distributions for parameters describing natural history and treatment-seeking behavior are informed by the literature or calibrated using national prevalence estimates. By combining them with surveillance data on numbers of chlamydia tests and diagnoses, we obtain estimates of local screening rates, incidence, and prevalence. We illustrate the method by application to data from England. Results: Our estimates of national prevalence by age group agree with the Natsal-3 survey. They could be improved by additional information on the number of diagnosed cases that were asymptomatic. There is substantial local-level variation in prevalence, with more infection in deprived areas. Incidence in each sex is strongly correlated with prevalence in the other. Importantly, we find that positivity (the proportion of tests which were positive) does not provide a reliable proxy for prevalence. Conclusion: This approach provides local chlamydia prevalence estimates from surveillance data, which could inform analyses to identify and understand local prevalence patterns and assess local programs. Estimates could be more accurate if surveillance systems recorded additional information, including on symptoms. See video abstract at, http://links.lww.com/EDE/B211. PMID:28306613

  20. Vibration band gaps for elastic metamaterial rods using wave finite element method

    NASA Astrophysics Data System (ADS)

    Nobrega, E. D.; Gautier, F.; Pelat, A.; Dos Santos, J. M. C.

    2016-10-01

    Band gaps in elastic metamaterial rods with spatial periodic distribution and periodically attached local resonators are investigated. New techniques to analyze metamaterial systems are using a combination of analytical or numerical method with wave propagation. One of them, called here wave spectral element method (WSEM), consists of combining the spectral element method (SEM) with Floquet-Bloch's theorem. A modern methodology called wave finite element method (WFEM), developed to calculate dynamic behavior in periodic acoustic and structural systems, utilizes a similar approach where SEM is substituted by the conventional finite element method (FEM). In this paper, it is proposed to use WFEM to calculate band gaps in elastic metamaterial rods with spatial periodic distribution and periodically attached local resonators of multi-degree-of-freedom (M-DOF). Simulated examples with band gaps generated by Bragg scattering and local resonators are calculated by WFEM and verified with WSEM, which is used as a reference method. Results are presented in the form of attenuation constant, vibration transmittance and frequency response function (FRF). For all cases, WFEM and WSEM results are in agreement, provided that the number of elements used in WFEM is sufficient to convergence. An experimental test was conducted with a real elastic metamaterial rod, manufactured with plastic in a 3D printer, without local resonance-type effect. The experimental results for the metamaterial rod with band gaps generated by Bragg scattering are compared with the simulated ones. Both numerical methods (WSEM and WFEM) can localize the band gap position and width very close to the experimental results. A hybrid approach combining WFEM with the commercial finite element software ANSYS is proposed to model complex metamaterial systems. Two examples illustrating its efficiency and accuracy to model an elastic metamaterial rod unit-cell using 1D simple rod element and 3D solid element are demonstrated and the results present good approximation to the experimental data.

  1. Exploring new topography-based subgrid spatial structures for improving land surface modeling

    DOE PAGES

    Tesfa, Teklu K.; Leung, Lai-Yung Ruby

    2017-02-22

    Topography plays an important role in land surface processes through its influence on atmospheric forcing, soil and vegetation properties, and river network topology and drainage area. Land surface models with a spatial structure that captures spatial heterogeneity, which is directly affected by topography, may improve the representation of land surface processes. Previous studies found that land surface modeling, using subbasins instead of structured grids as computational units, improves the scalability of simulated runoff and streamflow processes. In this study, new land surface spatial structures are explored by further dividing subbasins into subgrid structures based on topographic properties, including surface elevation,more » slope and aspect. Two methods (local and global) of watershed discretization are applied to derive two types of subgrid structures (geo-located and non-geo-located) over the topographically diverse Columbia River basin in the northwestern United States. In the global method, a fixed elevation classification scheme is used to discretize subbasins. The local method utilizes concepts of hypsometric analysis to discretize each subbasin, using different elevation ranges that also naturally account for slope variations. The relative merits of the two methods and subgrid structures are investigated for their ability to capture topographic heterogeneity and the implications of this on representations of atmospheric forcing and land cover spatial patterns. Results showed that the local method reduces the standard deviation (SD) of subgrid surface elevation in the study domain by 17 to 19 % compared to the global method, highlighting the relative advantages of the local method for capturing subgrid topographic variations. The comparison between the two types of subgrid structures showed that the non-geo-located subgrid structures are more consistent across different area threshold values than the geo-located subgrid structures. Altogether the local method and non-geo-located subgrid structures effectively and robustly capture topographic, climatic and vegetation variability, which is important for land surface modeling.« less

  2. Exploring new topography-based subgrid spatial structures for improving land surface modeling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tesfa, Teklu K.; Leung, Lai-Yung Ruby

    Topography plays an important role in land surface processes through its influence on atmospheric forcing, soil and vegetation properties, and river network topology and drainage area. Land surface models with a spatial structure that captures spatial heterogeneity, which is directly affected by topography, may improve the representation of land surface processes. Previous studies found that land surface modeling, using subbasins instead of structured grids as computational units, improves the scalability of simulated runoff and streamflow processes. In this study, new land surface spatial structures are explored by further dividing subbasins into subgrid structures based on topographic properties, including surface elevation,more » slope and aspect. Two methods (local and global) of watershed discretization are applied to derive two types of subgrid structures (geo-located and non-geo-located) over the topographically diverse Columbia River basin in the northwestern United States. In the global method, a fixed elevation classification scheme is used to discretize subbasins. The local method utilizes concepts of hypsometric analysis to discretize each subbasin, using different elevation ranges that also naturally account for slope variations. The relative merits of the two methods and subgrid structures are investigated for their ability to capture topographic heterogeneity and the implications of this on representations of atmospheric forcing and land cover spatial patterns. Results showed that the local method reduces the standard deviation (SD) of subgrid surface elevation in the study domain by 17 to 19 % compared to the global method, highlighting the relative advantages of the local method for capturing subgrid topographic variations. The comparison between the two types of subgrid structures showed that the non-geo-located subgrid structures are more consistent across different area threshold values than the geo-located subgrid structures. Altogether the local method and non-geo-located subgrid structures effectively and robustly capture topographic, climatic and vegetation variability, which is important for land surface modeling.« less

  3. Nonparametric Regression and the Parametric Bootstrap for Local Dependence Assessment.

    ERIC Educational Resources Information Center

    Habing, Brian

    2001-01-01

    Discusses ideas underlying nonparametric regression and the parametric bootstrap with an overview of their application to item response theory and the assessment of local dependence. Illustrates the use of the method in assessing local dependence that varies with examinee trait levels. (SLD)

  4. Fast localized orthonormal virtual orbitals which depend smoothly on nuclear coordinates.

    PubMed

    Subotnik, Joseph E; Dutoi, Anthony D; Head-Gordon, Martin

    2005-09-15

    We present here an algorithm for computing stable, well-defined localized orthonormal virtual orbitals which depend smoothly on nuclear coordinates. The algorithm is very fast, limited only by diagonalization of two matrices with dimension the size of the number of virtual orbitals. Furthermore, we require no more than quadratic (in the number of electrons) storage. The basic premise behind our algorithm is that one can decompose any given atomic-orbital (AO) vector space as a minimal basis space (which includes the occupied and valence virtual spaces) and a hard-virtual (HV) space (which includes everything else). The valence virtual space localizes easily with standard methods, while the hard-virtual space is constructed to be atom centered and automatically local. The orbitals presented here may be computed almost as quickly as projecting the AO basis onto the virtual space and are almost as local (according to orbital variance), while our orbitals are orthonormal (rather than redundant and nonorthogonal). We expect this algorithm to find use in local-correlation methods.

  5. Efficient Convex Optimization for Energy-Based Acoustic Sensor Self-Localization and Source Localization in Sensor Networks.

    PubMed

    Yan, Yongsheng; Wang, Haiyan; Shen, Xiaohong; Leng, Bing; Li, Shuangquan

    2018-05-21

    The energy reading has been an efficient and attractive measure for collaborative acoustic source localization in practical application due to its cost saving in both energy and computation capability. The maximum likelihood problems by fusing received acoustic energy readings transmitted from local sensors are derived. Aiming to efficiently solve the nonconvex objective of the optimization problem, we present an approximate estimator of the original problem. Then, a direct norm relaxation and semidefinite relaxation, respectively, are utilized to derive the second-order cone programming, semidefinite programming or mixture of them for both cases of sensor self-location and source localization. Furthermore, by taking the colored energy reading noise into account, several minimax optimization problems are formulated, which are also relaxed via the direct norm relaxation and semidefinite relaxation respectively into convex optimization problems. Performance comparison with the existing acoustic energy-based source localization methods is given, where the results show the validity of our proposed methods.

  6. Quantum localization for a kicked rotor with accelerator mode islands.

    PubMed

    Iomin, A; Fishman, S; Zaslavsky, G M

    2002-03-01

    Dynamical localization of classical superdiffusion for the quantum kicked rotor is studied in the semiclassical limit. Both classical and quantum dynamics of the system become more complicated under the conditions of mixed phase space with accelerator mode islands. Recently, long time quantum flights due to the accelerator mode islands have been found. By exploration of their dynamics, it is shown here that the classical-quantum duality of the flights leads to their localization. The classical mechanism of superdiffusion is due to accelerator mode dynamics, while quantum tunneling suppresses the superdiffusion and leads to localization of the wave function. Coupling of the regular type dynamics inside the accelerator mode island structures to dynamics in the chaotic sea proves increasing the localization length. A numerical procedure and an analytical method are developed to obtain an estimate of the localization length which, as it is shown, has exponentially large scaling with the dimensionless Planck's constant (tilde)h<1 in the semiclassical limit. Conditions for the validity of the developed method are specified.

  7. Globally maximizing, locally minimizing: unsupervised discriminant projection with applications to face and palm biometrics.

    PubMed

    Yang, Jian; Zhang, David; Yang, Jing-Yu; Niu, Ben

    2007-04-01

    This paper develops an unsupervised discriminant projection (UDP) technique for dimensionality reduction of high-dimensional data in small sample size cases. UDP can be seen as a linear approximation of a multimanifolds-based learning framework which takes into account both the local and nonlocal quantities. UDP characterizes the local scatter as well as the nonlocal scatter, seeking to find a projection that simultaneously maximizes the nonlocal scatter and minimizes the local scatter. This characteristic makes UDP more intuitive and more powerful than the most up-to-date method, Locality Preserving Projection (LPP), which considers only the local scatter for clustering or classification tasks. The proposed method is applied to face and palm biometrics and is examined using the Yale, FERET, and AR face image databases and the PolyU palmprint database. The experimental results show that UDP consistently outperforms LPP and PCA and outperforms LDA when the training sample size per class is small. This demonstrates that UDP is a good choice for real-world biometrics applications.

  8. Extensibility in local sensor based planning for hyper-redundant manipulators (robot snakes)

    NASA Technical Reports Server (NTRS)

    Choset, Howie; Burdick, Joel

    1994-01-01

    Partial Shape Modification (PSM) is a local sensor feedback method used for hyper-redundant robot manipulators, in which the redundancy is very large or infinite such as that of a robot snake. This aspect of redundancy enables local obstacle avoidance and end-effector placement in real time. Due to the large number of joints or actuators in a hyper-redundant manipulator, small displacement errors of such easily accumulate to large errors in the position of the tip relative to the base. The accuracy could be improved by a local sensor based planning method in which sensors are distributed along the length of the hyper-redundant robot. This paper extends the local sensor based planning strategy beyond the limitations of the fixed length of such a manipulator when its joint limits are met. This is achieved with an algorithm where the length of the deforming part of the robot is variable. Thus , the robot's local avoidance of obstacles is improved through the enhancement of its extensibility.

  9. Adaptive Local Realignment of Protein Sequences.

    PubMed

    DeBlasio, Dan; Kececioglu, John

    2018-06-11

    While mutation rates can vary markedly over the residues of a protein, multiple sequence alignment tools typically use the same values for their scoring-function parameters across a protein's entire length. We present a new approach, called adaptive local realignment, that in contrast automatically adapts to the diversity of mutation rates along protein sequences. This builds upon a recent technique known as parameter advising, which finds global parameter settings for an aligner, to now adaptively find local settings. Our approach in essence identifies local regions with low estimated accuracy, constructs a set of candidate realignments using a carefully-chosen collection of parameter settings, and replaces the region if a realignment has higher estimated accuracy. This new method of local parameter advising, when combined with prior methods for global advising, boosts alignment accuracy as much as 26% over the best default setting on hard-to-align protein benchmarks, and by 6.4% over global advising alone. Adaptive local realignment has been implemented within the Opal aligner using the Facet accuracy estimator.

  10. Efficient Convex Optimization for Energy-Based Acoustic Sensor Self-Localization and Source Localization in Sensor Networks

    PubMed Central

    Yan, Yongsheng; Wang, Haiyan; Shen, Xiaohong; Leng, Bing; Li, Shuangquan

    2018-01-01

    The energy reading has been an efficient and attractive measure for collaborative acoustic source localization in practical application due to its cost saving in both energy and computation capability. The maximum likelihood problems by fusing received acoustic energy readings transmitted from local sensors are derived. Aiming to efficiently solve the nonconvex objective of the optimization problem, we present an approximate estimator of the original problem. Then, a direct norm relaxation and semidefinite relaxation, respectively, are utilized to derive the second-order cone programming, semidefinite programming or mixture of them for both cases of sensor self-location and source localization. Furthermore, by taking the colored energy reading noise into account, several minimax optimization problems are formulated, which are also relaxed via the direct norm relaxation and semidefinite relaxation respectively into convex optimization problems. Performance comparison with the existing acoustic energy-based source localization methods is given, where the results show the validity of our proposed methods. PMID:29883410

  11. Localization of incipient tip vortex cavitation using ray based matched field inversion method

    NASA Astrophysics Data System (ADS)

    Kim, Dongho; Seong, Woojae; Choo, Youngmin; Lee, Jeunghoon

    2015-10-01

    Cavitation of marine propeller is one of the main contributing factors of broadband radiated ship noise. In this research, an algorithm for the source localization of incipient vortex cavitation is suggested. Incipient cavitation is modeled as monopole type source and matched-field inversion method is applied to find the source position by comparing the spatial correlation between measured and replicated pressure fields at the receiver array. The accuracy of source localization is improved by broadband matched-field inversion technique that enhances correlation by incoherently averaging correlations of individual frequencies. Suggested localization algorithm is verified through known virtual source and model test conducted in Samsung ship model basin cavitation tunnel. It is found that suggested localization algorithm enables efficient localization of incipient tip vortex cavitation using a few pressure data measured on the outer hull above the propeller and practically applicable to the typically performed model scale experiment in a cavitation tunnel at the early design stage.

  12. On the local field method with the account of spatial dispersion. Application to the optical activity theory

    NASA Astrophysics Data System (ADS)

    Tyu, N. S.; Ekhilevsky, S. G.

    1992-07-01

    For the perfect molecular crystals the equations of the local field method (LFM) with the account of spatial dispersion are formulated. They are used to derive the expression for the crystal polarizability tensor. For the first time within the framework of this method the formula for the gyrotropy tensor of an arbitrary optically active molecular crystal is obtained. This formula is analog of well known relationships of Lorentz-Lorenz.

  13. Real-time automatic registration in optical surgical navigation

    NASA Astrophysics Data System (ADS)

    Lin, Qinyong; Yang, Rongqian; Cai, Ken; Si, Xuan; Chen, Xiuwen; Wu, Xiaoming

    2016-05-01

    An image-guided surgical navigation system requires the improvement of the patient-to-image registration time to enhance the convenience of the registration procedure. A critical step in achieving this aim is performing a fully automatic patient-to-image registration. This study reports on a design of custom fiducial markers and the performance of a real-time automatic patient-to-image registration method using these markers on the basis of an optical tracking system for rigid anatomy. The custom fiducial markers are designed to be automatically localized in both patient and image spaces. An automatic localization method is performed by registering a point cloud sampled from the three dimensional (3D) pedestal model surface of a fiducial marker to each pedestal of fiducial markers searched in image space. A head phantom is constructed to estimate the performance of the real-time automatic registration method under four fiducial configurations. The head phantom experimental results demonstrate that the real-time automatic registration method is more convenient, rapid, and accurate than the manual method. The time required for each registration is approximately 0.1 s. The automatic localization method precisely localizes the fiducial markers in image space. The averaged target registration error for the four configurations is approximately 0.7 mm. The automatic registration performance is independent of the positions relative to the tracking system and the movement of the patient during the operation.

  14. A hybrid neural learning algorithm using evolutionary learning and derivative free local search method.

    PubMed

    Ghosh, Ranadhir; Yearwood, John; Ghosh, Moumita; Bagirov, Adil

    2006-06-01

    In this paper we investigate a hybrid model based on the Discrete Gradient method and an evolutionary strategy for determining the weights in a feed forward artificial neural network. Also we discuss different variants for hybrid models using the Discrete Gradient method and an evolutionary strategy for determining the weights in a feed forward artificial neural network. The Discrete Gradient method has the advantage of being able to jump over many local minima and find very deep local minima. However, earlier research has shown that a good starting point for the discrete gradient method can improve the quality of the solution point. Evolutionary algorithms are best suited for global optimisation problems. Nevertheless they are cursed with longer training times and often unsuitable for real world application. For optimisation problems such as weight optimisation for ANNs in real world applications the dimensions are large and time complexity is critical. Hence the idea of a hybrid model can be a suitable option. In this paper we propose different fusion strategies for hybrid models combining the evolutionary strategy with the discrete gradient method to obtain an optimal solution much quicker. Three different fusion strategies are discussed: a linear hybrid model, an iterative hybrid model and a restricted local search hybrid model. Comparative results on a range of standard datasets are provided for different fusion hybrid models.

  15. Constrained spectral clustering under a local proximity structure assumption

    NASA Technical Reports Server (NTRS)

    Wagstaff, Kiri; Xu, Qianjun; des Jardins, Marie

    2005-01-01

    This work focuses on incorporating pairwise constraints into a spectral clustering algorithm. A new constrained spectral clustering method is proposed, as well as an active constraint acquisition technique and a heuristic for parameter selection. We demonstrate that our constrained spectral clustering method, CSC, works well when the data exhibits what we term local proximity structure.

  16. An Examination of Rater Performance on a Local Oral English Proficiency Test: A Mixed-Methods Approach

    ERIC Educational Resources Information Center

    Yan, Xun

    2014-01-01

    This paper reports on a mixed-methods approach to evaluate rater performance on a local oral English proficiency test. Three types of reliability estimates were reported to examine rater performance from different perspectives. Quantitative results were also triangulated with qualitative rater comments to arrive at a more representative picture of…

  17. Research on social communication network evolution based on topology potential distribution

    NASA Astrophysics Data System (ADS)

    Zhao, Dongjie; Jiang, Jian; Li, Deyi; Zhang, Haisu; Chen, Guisheng

    2011-12-01

    Aiming at the problem of social communication network evolution, first, topology potential is introduced to measure the local influence among nodes in networks. Second, from the perspective of topology potential distribution the method of network evolution description based on topology potential distribution is presented, which takes the artificial intelligence with uncertainty as basic theory and local influence among nodes as essentiality. Then, a social communication network is constructed by enron email dataset, the method presented is used to analyze the characteristic of the social communication network evolution and some useful conclusions are got, implying that the method is effective, which shows that topology potential distribution can effectively describe the characteristic of sociology and detect the local changes in social communication network.

  18. G‐LoSA: An efficient computational tool for local structure‐centric biological studies and drug design

    PubMed Central

    2016-01-01

    Abstract Molecular recognition by protein mostly occurs in a local region on the protein surface. Thus, an efficient computational method for accurate characterization of protein local structural conservation is necessary to better understand biology and drug design. We present a novel local structure alignment tool, G‐LoSA. G‐LoSA aligns protein local structures in a sequence order independent way and provides a GA‐score, a chemical feature‐based and size‐independent structure similarity score. Our benchmark validation shows the robust performance of G‐LoSA to the local structures of diverse sizes and characteristics, demonstrating its universal applicability to local structure‐centric comparative biology studies. In particular, G‐LoSA is highly effective in detecting conserved local regions on the entire surface of a given protein. In addition, the applications of G‐LoSA to identifying template ligands and predicting ligand and protein binding sites illustrate its strong potential for computer‐aided drug design. We hope that G‐LoSA can be a useful computational method for exploring interesting biological problems through large‐scale comparison of protein local structures and facilitating drug discovery research and development. G‐LoSA is freely available to academic users at http://im.compbio.ku.edu/GLoSA/. PMID:26813336

  19. G-LoSA: An efficient computational tool for local structure-centric biological studies and drug design.

    PubMed

    Lee, Hui Sun; Im, Wonpil

    2016-04-01

    Molecular recognition by protein mostly occurs in a local region on the protein surface. Thus, an efficient computational method for accurate characterization of protein local structural conservation is necessary to better understand biology and drug design. We present a novel local structure alignment tool, G-LoSA. G-LoSA aligns protein local structures in a sequence order independent way and provides a GA-score, a chemical feature-based and size-independent structure similarity score. Our benchmark validation shows the robust performance of G-LoSA to the local structures of diverse sizes and characteristics, demonstrating its universal applicability to local structure-centric comparative biology studies. In particular, G-LoSA is highly effective in detecting conserved local regions on the entire surface of a given protein. In addition, the applications of G-LoSA to identifying template ligands and predicting ligand and protein binding sites illustrate its strong potential for computer-aided drug design. We hope that G-LoSA can be a useful computational method for exploring interesting biological problems through large-scale comparison of protein local structures and facilitating drug discovery research and development. G-LoSA is freely available to academic users at http://im.compbio.ku.edu/GLoSA/. © 2016 The Protein Society.

  20. Signal-to-noise ratio comparison of encoding methods for hyperpolarized noble gas MRI

    NASA Technical Reports Server (NTRS)

    Zhao, L.; Venkatesh, A. K.; Albert, M. S.; Panych, L. P.

    2001-01-01

    Some non-Fourier encoding methods such as wavelet and direct encoding use spatially localized bases. The spatial localization feature of these methods enables optimized encoding for improved spatial and temporal resolution during dynamically adaptive MR imaging. These spatially localized bases, however, have inherently reduced image signal-to-noise ratio compared with Fourier or Hadamad encoding for proton imaging. Hyperpolarized noble gases, on the other hand, have quite different MR properties compared to proton, primarily the nonrenewability of the signal. It could be expected, therefore, that the characteristics of image SNR with respect to encoding method will also be very different from hyperpolarized noble gas MRI compared to proton MRI. In this article, hyperpolarized noble gas image SNRs of different encoding methods are compared theoretically using a matrix description of the encoding process. It is shown that image SNR for hyperpolarized noble gas imaging is maximized for any orthonormal encoding method. Methods are then proposed for designing RF pulses to achieve normalized encoding profiles using Fourier, Hadamard, wavelet, and direct encoding methods for hyperpolarized noble gases. Theoretical results are confirmed with hyperpolarized noble gas MRI experiments. Copyright 2001 Academic Press.

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