Physical response of a back-barrier estuary to a post-tropical cyclone

USGS Publications Warehouse

Beudin, Alexis; Ganju, Neil Kamal; Defne, Zafer; Aretxabaleta, Alfredo

2017-01-01

This paper presents a modeling investigation of the hydrodynamic and sediment transport response of Chincoteague Bay (VA/MD, USA) to Hurricane Sandy using the Coupled Ocean-Atmosphere-Wave-Sediment-Transport (COAWST) modeling system. Several simulation scenarios with different combinations of remote and local forces were conducted to identify the dominant physical processes. While 80% of the water level increase in the bay was due to coastal sea level at the peak of the storm, a rich spatial and temporal variability in water surface slope was induced by local winds and waves. Local wind increased vertical mixing, horizontal exchanges, and flushing through the inlets. Remote waves (swell) enhanced southward flow through wave setup gradients between the inlets, and increased locally generated wave heights. Locally generated waves had a negligible effect on water level but reduced the residual flow up to 70% due to enhanced apparent roughness and breaking-induced forces. Locally generated waves dominated bed shear stress and sediment resuspension in the bay. Sediment transport patterns mirrored the interior coastline shape and generated deposition on inundated areas. The bay served as a source of fine sediment to the inner shelf, and the ocean-facing barrier island accumulated sand from landward-directed overwash. Despite the intensity of the storm forcing, the bathymetric changes in the bay were on the order of centimeters. This work demonstrates the spectrum of responses to storm forcing, and highlights the importance of local and remote processes on back-barrier estuarine function.

Public Health Education in Florida.

ERIC Educational Resources Information Center

Florida State Dept. of Education, Tallahassee.

This report documents issues related to the work of the Florida Comprehensive Health Professions Education Plan. Public health education prepares students for initial employment or advancement in a number of positions. While the public health work force is primarily employed in various units in local, state, and federal governments, industry also…

The earthquake disaster risk characteristic and the problem in the earthquake emergency rescue of mountainous southwestern Sichuan

NASA Astrophysics Data System (ADS)

Yuan, S.; Xin, C.; Ying, Z.

2016-12-01

In recent years, earthquake disaster occurred frequently in Chinese mainland, the secondary disaster which have been caused by it is more serious in mountainous region. Because of the influence of terrain and geological conditions, the difficulty of earthquake emergency rescue work greatly increased, rescue force is also urged. Yet, it has been studied less on earthquake emergency rescue in mountainous region, the research in existing equipment whether can meet the actual needs of local earthquake emergency rescue is poorly. This paper intends to discuss and solve these problems. Through the mountainous regions Ganzi and Liangshan states in Sichuan field research, we investigated the process of earthquake emergency response and the projects for rescue force after an earthquake, and we also collected and collated local rescue force based data. By consulting experts and statistical analyzing the basic data, there are mainly two problems: The first is about local rescue force, they are poorly equipped and lack in the knowledge of medical help or identify architectural structure. There are no countries to establish a sound financial investment protection mechanism. Also, rescue equipment's updates and maintenance; The second problem is in earthquake emergency rescue progress. In the complicated geologic structure of mountainous regions, traffic and communication may be interrupted by landslides and mud-rock flows after earthquake. The outside rescue force may not arrive in time, rescue equipment was transported by manpower. Because of unknown earthquake disaster information, the local rescue force was deployed unreasonable. From the above, the local government worker should analyze the characteristics of the earthquake disaster in mountainous regions, and research how to improve their earthquake emergency rescue ability. We think they can do that by strengthening and regulating the rescue force structure, enhancing the skills and knowledge, training rescue workers, outfitting the light and portable rescue equipment, improving the public's self and mutual aid ability. All these measures will help local government reach the final goal of reducing the earthquake disaster.

[Occupational stress of assembly line female workers in confectionery work].

PubMed

Kondo, Y; Sato, Y; Takashima, H; Siki, T; Inui, S; Arachi, H; Yamashita, N; Hosokawa, M

1985-09-01

Concomitant with frequent occurrence of disorders of the neck, arm, hand and low back among assembly-line female workers in confectionery work, there is an increased number of patients with occupational cervicobrachial disorders and/or low back pain. In suspicion of the close correlation between the working conditions and development of these local disorders, a field study was undertaken. The following are the results obtained. More than 90% of these assembly-line female workers consisted of inexperienced part-time employees, mostly of middle to old age. They were engaged in decorating conveyor-carried cakes with cream and chocolate. The work necessitated repetitive movements of the upper limbs and concentration of visuosensory and nervous attention in a half-sitting slouching posture. This was considered to exert excess load on the local muscles and nervous and sensory systems. The causes that intensified the local symptoms as pointed out by the workers consisted of (1) repetitive use of the arms and hands, (2) static posture during the work and (3) sustained standing position. Complaints of low back pain were conspicuous from the unsuitable height of a conveyor-belt. Thirty five percent of the female workers needed medical treatment for cervicobrachial and/or low back pain. The forced adaptation to the belt height, sustained unnatural working posture and the imposition of forced movements seemed to be the main factors in the onset of cervicobrachial and/or low back pain in interrelation with working hours. On the basis of these results, the work load on a machine-paced assembly-line was analyzed and the necessity of improvement of working conditions was discussed.

Workforce Investment Act Youth Provisions and School-to-Work Opportunities: A Context for Collaboration.

ERIC Educational Resources Information Center

Spangler, D.

This document is intended to help existing school-to-work (STW) partnerships and the new local work force investment boards understand the opportunities for achieving common ground to better serve youth during implementation of the Workforce Investment Act (WIA) and formation of the new youth councils. The following are among the topics discussed:…

The Disquieting Tension of "The Other": International Students' Experience of Sojourn in Hong Kong

ERIC Educational Resources Information Center

Ladegaard, Hans J.

2017-01-01

Recent research has shown that increasing the number of international students and staff in universities does not necessarily make the campus more "international". Ladegaard and Cheng (2014) found that local and non-local students live completely separate lives on campus and do not work together, let alone socialise, unless forced to do…

‘The dangers attending these conditions are evident’: Public Health and the Working Environment of Lancashire Textile Communities, c.1870–1939

PubMed Central

Greenlees, Janet

2013-01-01

This article examines the position of the working environment within public health priorities and as a contributor to the health of a community. Using two Lancashire textile towns (Burnley and Blackburn) as case studies and drawing on a variety of sources, it highlights how, while legislation set the industry parameters for legal enforcement of working conditions, local public health priorities were pivotal in setting codes of practice. The complexities entwined with identifying the working environment as a cause of ill health and with improving it were entangled within the local community health context. In addition, the multiple understandings of Medical Officers of Health surrounding the remit of their responsibilities impacted the local health context. These did not always parallel national regulations. Indeed, it was these local, community specific forces that set the public health agenda, determined its path and the place of the working environment within this. PMID:24771979

Calculation of forces on magnetized bodies using COSMIC NASTRAN

NASA Technical Reports Server (NTRS)

Sheerer, John

1987-01-01

The methods described may be used with a high degree of confidence for calculations of magnetic traction forces normal to a surface. In this circumstance all models agree, and test cases have resulted in theoretically correct results. It is shown that the tangential forces are in practice negligible. The surface pole method is preferable to the virtual work method because of the necessity for more than one NASTRAN run in the latter case, and because distributed forces are obtained. The derivation of local forces from the Maxwell stress method involves an undesirable degree of manipulation of the problem and produces a result in contradiction of the surface pole method.

Dynamically Consistent Parameterization of Mesoscale Eddies This work aims at parameterization of eddy effects for use in non-eddy-resolving ocean models and focuses on the effect of the stochastic part of the eddy forcing that backscatters and induces eastward jet extension of the western boundary currents and its adjacent recirculation zones.

NASA Astrophysics Data System (ADS)

Berloff, P. S.

2016-12-01

This work aims at developing a framework for dynamically consistent parameterization of mesoscale eddy effects for use in non-eddy-resolving ocean circulation models. The proposed eddy parameterization framework is successfully tested on the classical, wind-driven double-gyre model, which is solved both with explicitly resolved vigorous eddy field and in the non-eddy-resolving configuration with the eddy parameterization replacing the eddy effects. The parameterization focuses on the effect of the stochastic part of the eddy forcing that backscatters and induces eastward jet extension of the western boundary currents and its adjacent recirculation zones. The parameterization locally approximates transient eddy flux divergence by spatially localized and temporally periodic forcing, referred to as the plunger, and focuses on the linear-dynamics flow solution induced by it. The nonlinear self-interaction of this solution, referred to as the footprint, characterizes and quantifies the induced eddy forcing exerted on the large-scale flow. We find that spatial pattern and amplitude of each footprint strongly depend on the underlying large-scale flow, and the corresponding relationships provide the basis for the eddy parameterization and its closure on the large-scale flow properties. Dependencies of the footprints on other important parameters of the problem are also systematically analyzed. The parameterization utilizes the local large-scale flow information, constructs and scales the corresponding footprints, and then sums them up over the gyres to produce the resulting eddy forcing field, which is interactively added to the model as an extra forcing. Thus, the assumed ensemble of plunger solutions can be viewed as a simple model for the cumulative effect of the stochastic eddy forcing. The parameterization framework is implemented in the simplest way, but it provides a systematic strategy for improving the implementation algorithm.

Campus Policing: The Nature of University Police Work.

ERIC Educational Resources Information Center

Bordner, Diane C.; Petersen, David M.

Various aspects of campus police work are described, including the actual duties of officers, staff selection and training, and the larger issues of law enforcement. The urban university police is the focus, and comparisons are made to the organization and activities of other urban police forces. Also considered is the local context for different…

Reboundarying Professional Jurisdiction: Educational Work on Discount Sale

ERIC Educational Resources Information Center

Henriksson, Lea

2014-01-01

Education is a critical instrument for governments and communities managing economic and social development in global times. Reboundarying educational work reflects this dynamic where the national and local are networked in complex ways. In this frame, the focus in this article is on a policy debate on educational labour force and gendered work…

Sustaining engagement through work in postdisaster relief and reconstruction.

PubMed

Wang, Xiao Lu; Shi, Zhan Biao; Ng, Siu Man; Wang, Bin; Chan, Cecilia L W

2011-04-01

After the devastating 2008 earthquake in China, grass-roots government officials were the main local force in postquake relief and reconstruction. Like other survivors, many officials were severely bereaved. Their psychological well-being was at stake. We conducted 25 semistructured interviews to investigate sources of stress at work and their coping experiences. We coded interviews using the content analysis method. Misunderstandings and assaults from survivors, prolonged heavy workload, and grief and bereavement were major sources of stress at work. Finding meaning in the work, emotion regulation, and goal and time management were main coping strategies. The challenge and importance of the work, combined with support and recognition at work, fostered an empowering work environment. Few interviewees reported fatigue, whereas the majority displayed dedication to work, indicating a status of work engagement more than burnout among grass-roots officials. Implications of a meaning-oriented empowerment approach to stress management for disaster relief forces are drawn.

Command and Control Warfare. Putting Another Tool in the War-Fighter’s Data Base

DTIC Science & Technology

1994-09-01

information dominance , friendly commanders will be able to work inside the enemy commander’s decision-making cycle forcing him to be reactive and thus cede the initiative and advantage to friendly forces. In any conflict, from large scale transregional to small scale, localized counter-insurgency, a joint or coalition team drawn together from the capabilities of each service and orchestrated by the joint force or theater- level commander will execute the responses of the United States armed forces. Units should perform their specific roles in accordance with the

ACHP | Task Force on Rightsizing and Historic Preservation

Science.gov Websites

commitment from the National Park Service and the hard work of local residents. For example, the neighborhood neighborhood which was hit hard by the foreclosure crisis. While maintaining historic integrity, revitalization

The Research Library's Role in Digital Repository Services: Final Report of the ARL Digital Repository Issues Task Force

ERIC Educational Resources Information Center

Association of Research Libraries, 2009

2009-01-01

Libraries are making diverse contributions to the development of many types of digital repositories, particularly those housing locally created digital content, including new digital objects or digitized versions of locally held works. In some instances, libraries are managing a repository and its related services entirely on their own, but often…

Trapping charges at grain boundaries and degradation of CH3NH3Pb(I1-x Br x )3 perovskite solar cells.

PubMed

Nguyen, Bich Phuong; Kim, Gee Yeong; Jo, William; Kim, Byeong Jo; Jung, Hyun Suk

2017-08-04

The electrical properties of CH 3 NH 3 Pb(I 1-x Br x ) 3 (x = 0.13) perovskite materials were investigated under ambient conditions. The local work function and the local current were measured using Kelvin probe force microscopy and conductive atomic force microscopy, respectively. The degradation of the perovskite layers depends on their grain size. As the material degrades, an additional peak in the surface potential appears simultaneously with a sudden increase and subsequent relaxation of the local current. The potential bending at the grain boundaries and the intragrains is the most likely reason for the change of the local current surface of the perovskite layers. The improved understanding of the degradation mechanism garnered from this study helps pave the way toward an improved photo-conversion efficiency in perovskite solar cells.

Trapping charges at grain boundaries and degradation of CH3NH3Pb(I1-x Br x )3 perovskite solar cells

NASA Astrophysics Data System (ADS)

Phuong Nguyen, Bich; Kim, Gee Yeong; Jo, William; Kim, Byeong Jo; Jung, Hyun Suk

2017-08-01

The electrical properties of CH3NH3Pb(I1-x Br x )3 (x = 0.13) perovskite materials were investigated under ambient conditions. The local work function and the local current were measured using Kelvin probe force microscopy and conductive atomic force microscopy, respectively. The degradation of the perovskite layers depends on their grain size. As the material degrades, an additional peak in the surface potential appears simultaneously with a sudden increase and subsequent relaxation of the local current. The potential bending at the grain boundaries and the intragrains is the most likely reason for the change of the local current surface of the perovskite layers. The improved understanding of the degradation mechanism garnered from this study helps pave the way toward an improved photo-conversion efficiency in perovskite solar cells.

Numerical and experimental study on vorticity measurement in liquid metal using local Lorentz force velocimetry

NASA Astrophysics Data System (ADS)

Hernández, Daniel; Marangoni, Rafael; Schleichert, Jan; Karcher, Christian; Fröhlich, Thomas; Wondrak, Thomas

2018-03-01

Local Lorentz force velocimetry (local LFV) is a contactless velocity measurement technique for liquid metals. Due to the relative movement between an electrically conductive fluid and a static applied magnetic field, eddy currents and a flow-braking Lorentz force are generated inside the metal melt. This force is proportional to the flow rate or to the local velocity, depending on the volume subset of the flow spanned by the magnetic field. By using small-size magnets, a localized magnetic field distribution is achieved allowing a local velocity assessment in the region adjacent to the wall. In the present study, we describe a numerical model of our experiments at a continuous caster model where the working fluid is GaInSn in eutectic composition. Our main goal is to demonstrate that this electromagnetic technique can be applied to measure vorticity distributions, i.e. to resolve velocity gradients as well. Our results show that by using a cross-shaped magnet system, the magnitude of the torque perpendicular to the surface of the mold significantly increases improving its measurement in a liquid metal flow. According to our numerical model, this torque correlates with the vorticity of the velocity in this direction. Before validating our numerical predictions, an electromagnetic dry calibration of the measurement system composed of a multicomponent force and torque sensor and a cross-shaped magnet was done using a rotating disk made of aluminum. The sensor is able to measure simultaneously all three components of force and torque, respectively. This calibration step cannot be avoided and it is used for an accurate definition of the center of the magnet with respect to the sensor’s coordinate system for torque measurements. Finally, we present the results of the experiments at the mini-LIMMCAST facility showing a good agreement with the numerical model.

ACHP | Working Together to Build a More Inclusive Preservation Program

Science.gov Websites

goal is to better position folklorists and folklore methodologies as central forces in historic . Folklore methodologies can help engage the local community and elicit their voices. As the National Park

Schedule of average annual equipment ownership expense

DOT National Transportation Integrated Search

2003-03-06

The "Schedule of Average Annual Equipment Ownership Expense" is designed for use on Force Account bills of Contractors performing work for the Illinois Department of Transportation and local government agencies who choose to adopt these rates. This s...

Probing local work function of electron emitting Si-nanofacets

NASA Astrophysics Data System (ADS)

Basu, Tanmoy; Som, Tapobrata

2017-10-01

Large area, Si-nanofacets are synthesized by obliquely incident low energy Ar+-ion-beam bombardment at room temperature (RT). The field emission properties of such nanofacets are studied based on current-voltage measurements and the Fowler-Nordheim equation. Low turn-on field with relatively high current density is obtained due to the shape and an overall rough morphology. We demonstrate a tunable field emission property from the silicon nanofacets by varying the ion exposure time. Atomic force microscopy (AFM) in conjunction with Kelvin probe force microscopy (KPFM) measurements provide the information on the aspect ratio and confirms the presence of native oxide layer near the apexes of the facets, respectively. The inhomogeneous oxidation leads to an increase in the local work function at the apexes of the facets, restricting the electron emission from the same. Due to its room temperature fabrication, the present method is of great significance to the low-cost vacuum field emission devices fabrication.

Applied Meteorology Unit Quarterly Report, Second Quarter FY-13

NASA Technical Reports Server (NTRS)

Bauman, William; Crawford, Winifred; Watson, Leela; Shafer, Jaclyn; Huddleston, Lisa

2013-01-01

The AMU team worked on six tasks for their customers: (1) Ms. Crawford continued work on the objective lightning forecast task for airports in east-central Florida, and began work on developing a dual-Doppler analysis with local Doppler radars, (2) Ms. Shafer continued work for Vandenberg Air Force Base on an automated tool to relate pressure gradients to peak winds, (3) Dr. Huddleston continued work to develop a lightning timing forecast tool for the Kennedy Space Center/Cape Canaveral Air Force Station area, (4) Dr. Bauman continued work on a severe weather forecast tool focused on east-central Florida, (5) Mr. Decker began developing a wind pairs database for the Launch Services Program to use when evaluating upper-level winds for launch vehicles, and (6) Dr. Watson began work to assimilate observational data into the high-resolution model configurations, she created for Wallops Flight Facility and the Eastern Range.

The Portfolio Project: A Study of Assessment, Instruction, and Middle School Reform.

ERIC Educational Resources Information Center

Underwood, Terry

This book is a study, in research-based narrative form, of one middle school's implementation of a new portfolio assessment plan in response to statewide policy changes in California. The book highlights the interactions of state, district, and local forces as teachers work to implement a portfolio-assessment plan that collects student work and…

Indenting a Thin Floating Film: Force and First-fold Formation

NASA Astrophysics Data System (ADS)

Ripp, Monica; Paulsen, Joseph

2017-11-01

When a thin elastic sheet is gently pushed into a liquid bath, a pattern of radial wrinkles is generated where the film is locally compressed. Despite the simplicity of this setting, basic questions remain about the mechanics and morphology of indented thin films. Recent work shows that traditional post-buckling analysis must be supplanted with an analysis where wrinkles completely relax compressive stresses. Support for this ``far-from-threshold'' theory has been built on measurements of wrinkle extent and wavelength, but direct force measurements have been absent. Here we measure the force response of floating ultrathin ( 100 nm) polystyrene films in indentation experiments. Our measurements are in good agreement with recent predictions for two regimes of poking: Early on force depends on film properties (thickness and Young's modulus) and later is independent of film properties, simply transferring forces from the substrate (gravity and surface tension) to the poker. At larger indentations compression localizes into a single fold. We present scaling arguments and experiments that show the existing model of this transition must be modified. NSF IGERT, NSF CAREER.

A convex optimization method for self-organization in dynamic (FSO/RF) wireless networks

NASA Astrophysics Data System (ADS)

Llorca, Jaime; Davis, Christopher C.; Milner, Stuart D.

2008-08-01

Next generation communication networks are becoming increasingly complex systems. Previously, we presented a novel physics-based approach to model dynamic wireless networks as physical systems which react to local forces exerted on network nodes. We showed that under clear atmospheric conditions the network communication energy can be modeled as the potential energy of an analogous spring system and presented a distributed mobility control algorithm where nodes react to local forces driving the network to energy minimizing configurations. This paper extends our previous work by including the effects of atmospheric attenuation and transmitted power constraints in the optimization problem. We show how our new formulation still results in a convex energy minimization problem. Accordingly, an updated force-driven mobility control algorithm is presented. Forces on mobile backbone nodes are computed as the negative gradient of the new energy function. Results show how in the presence of atmospheric obscuration stronger forces are exerted on network nodes that make them move closer to each other, avoiding loss of connectivity. We show results in terms of network coverage and backbone connectivity and compare the developed algorithms for different scenarios.

The concept of physical surface in nuclear matter

NASA Astrophysics Data System (ADS)

Mazilu, Nicolae; Agop, Maricel

2015-02-01

The main point of a physical definition of surface forces in the matter in general, especially in the nuclear matter, is that the curvature of surfaces and its variation should be physically defined. The forces are therefore just the vehicles of introducing physics. The problem of mathematical definition of a surface in term of the curvature parameters thus naturally occurs. The present work addresses this problem in terms of the asymptotic directions of a surface in a point. A physical meaning of these parameters is given, first in terms of inertial forces, then in terms of a differential theory of colors, whereby the space of curvature parameters is identified with the color space. The work concludes with an image of the evolution of a local portion of a surface.

Biophysical force regulation in 3D tumor cell invasion

NASA Astrophysics Data System (ADS)

Wu, Mingming

When embedded within 3D extracellular matrices (ECM), animal cells constantly probe and adapt to the ECM locally (at cell length scale) and exert forces and communicate with other cells globally (up to 10 times of cell length). It is now well accepted that mechanical crosstalk between animal cells and their microenvironment critically regulate cell function such as migration, proliferation and differentiation. Disruption of the cell-ECM crosstalk is implicated in a number of pathologic processes including tumor progression and fibrosis. Central to the problem of cell-ECM crosstalk is the physical force that cells generate. By measuring single cell generated force within 3D collagen matrices, we revealed a mechanical crosstalk mechanism between the tumor cells and the ECM. Cells generate sufficient force to stiffen collagen fiber network, and stiffer matrix, in return promotes larger cell force generation. Our work highlights the importance of fibrous nonlinear elasticity in regulating tumor cell-ECM interaction, and results may have implications in the rapid tissue stiffening commonly found in tumor progression and fibrosis. This work is partially supported by NIH Grants R21RR025801 and R21GM103388.

Keeping Special Forces Special: Regional Proficiency in Special Forces

DTIC Science & Technology

2011-12-01

Dr. David Brand provided the foundation for this thesis. Well before it was newsworthy, DRSE was hard at work seeking to improve the education of...had personally dealt with many of the Northern Alliance commanders.3 Had the timing of 9/11 been different, Schroen could have retired and there...and alliance in a region.”72 Often military personnel view local social structures through strictly a tribal lens. As Varhola and Varhola explain

Probing Cytoskeletal Structures by Coupling Optical Superresolution and AFM Techniques for a Correlative Approach

PubMed Central

Chacko, Jenu Varghese; Zanacchi, Francesca Cella; Diaspro, Alberto

2013-01-01

In this article, we describe and show the application of some of the most advanced fluorescence superresolution techniques, STED AFM and STORM AFM microscopy towards imaging of cytoskeletal structures, such as microtubule filaments. Mechanical and structural properties can play a relevant role in the investigation of cytoskeletal structures of interest, such as microtubules, that provide support to the cell structure. In fact, the mechanical properties, such as the local stiffness and the elasticity, can be investigated by AFM force spectroscopy with tens of nanometers resolution. Force curves can be analyzed in order to obtain the local elasticity (and the Young's modulus calculation by fitting the force curves from every pixel of interest), and the combination with STED/STORM microscopy integrates the measurement with high specificity and yields superresolution structural information. This hybrid modality of superresolution-AFM working is a clear example of correlative multimodal microscopy. PMID:24027190

Calibrated work function mapping by Kelvin probe force microscopy

NASA Astrophysics Data System (ADS)

Fernández Garrillo, Pablo A.; Grévin, Benjamin; Chevalier, Nicolas; Borowik, Łukasz

2018-04-01

We propose and demonstrate the implementation of an alternative work function tip calibration procedure for Kelvin probe force microscopy under ultrahigh vacuum, using monocrystalline metallic materials with known crystallographic orientation as reference samples, instead of the often used highly oriented pyrolytic graphite calibration sample. The implementation of this protocol allows the acquisition of absolute and reproducible work function values, with an improved uncertainty with respect to unprepared highly oriented pyrolytic graphite-based protocols. The developed protocol allows the local investigation of absolute work function values over nanostructured samples and can be implemented in electronic structures and devices characterization as demonstrated over a nanostructured semiconductor sample presenting Al0.7Ga0.3As and GaAs layers with variable thickness. Additionally, using our protocol we find that the work function of annealed highly oriented pyrolytic graphite is equal to 4.6 ± 0.03 eV.

A numerical study of mixing in stationary, nonpremixed, turbulent reacting flows

NASA Astrophysics Data System (ADS)

Overholt, Matthew Ryan

1998-10-01

In this work a detailed numerical study is made of a statistically-stationary, non-premixed, turbulent reacting model flow known as Periodic Reaction Zones. The mixture fraction-progress variable approach is used, with a mean gradient in the mixture fraction and a model, single-step, reversible, finite-rate thermochemistry, yielding both stationary and local extinction behavior. The passive scalar is studied first, using a statistical forcing scheme to achieve stationarity of the velocity field. Multiple independent direct numerical simulations (DNS) are performed for a wide range of Reynolds numbers with a number of results including a bilinear model for scalar mixing jointly conditioned on the scalar and x2-component of velocity, Gaussian scalar probability density function tails which were anticipated to be exponential, and the quantification of the dissipation of scalar flux. A new deterministic forcing scheme for DNS is then developed which yields reduced fluctuations in many quantities and a more natural evolution of the velocity fields. This forcing method is used for the final portion of this work. DNS results for Periodic Reaction Zones are compared with the Conditional Moment Closure (CMC) model, the Quasi-Equilibrium Distributed Reaction (QEDR) model, and full probability density function (PDF) simulations using the Euclidean Minimum Spanning Tree (EMST) and the Interaction by Exchange with the Mean (IEM) mixing models. It is shown that CMC and QEDR results based on the local scalar dissipation match DNS wherever local extinction is not present. However, due to the large spatial variations of scalar dissipation, and hence local Damkohler number, local extinction is present even when the global Damkohler number is twenty-five times the critical value for extinction. Finally, in the PDF simulations the EMST mixing model closely reproduces CMC and DNS results when local extinction is not present, whereas the IEM model results in large error.

Uniformed Diplomacy: Reviewing the Army Leader Development Strategy in Light of the Regional Alignment of Forces Construct

DTIC Science & Technology

2014-06-13

Component Command. Developing this operational flexibility, Army Chief of Staff General Raymond Odierno believes, will help improve the effectiveness of...days of arriving in Africa, he and 45 other soldiers found themselves “working with local forces and U.S. Embassy staff to stiffen protection at the...missions, neither USARAF nor DOS have fully developed measure of effectiveness criteria for these deployments.35 Thus far each mission’s after action

Fiber based optical tweezers for simultaneous in situ force exertion and measurements in a 3D polyacrylamide gel compartment.

PubMed

Ti, Chaoyang; Thomas, Gawain M; Ren, Yundong; Zhang, Rui; Wen, Qi; Liu, Yuxiang

2015-07-01

Optical tweezers play an important role in biological applications. However, it is difficult for traditional optical tweezers based on objective lenses to work in a three-dimensional (3D) solid far away from the substrate. In this work, we develop a fiber based optical trapping system, namely inclined dual fiber optical tweezers, that can simultaneously apply and measure forces both in water and in a 3D polyacrylamide gel matrix. In addition, we demonstrate in situ, non-invasive characterization of local mechanical properties of polyacrylamide gel by measurements on an embedded bead. The fiber optical tweezers measurements agree well with those of atomic force microscopy (AFM). The inclined dual fiber optical tweezers provide a promising and versatile tool for cell mechanics study in 3D environments.

Inflammation and the pathophysiology of work-related musculoskeletal disorders.

PubMed

Barbe, Mary F; Barr, Ann E

2006-09-01

Work-related musculoskeletal disorders (MSDs) have accounted for a significant proportion of work injuries and workers' compensation claims in industrialized nations since the late 1980s. Despite epidemiological evidence for the role of repetition and force in the onset and progression of work-related MSDs, complete understanding of these important occupational health problems requires further elucidation of pathophysiological mechanisms of the tissue response, particularly in the early stage of these disorders. Results from several clinical and experimental studies indicate that tissue microtraumas occur as a consequence of performing repetitive and/or forceful tasks, and that this mechanical tissue injury leads to local and perhaps even systemic inflammation, followed by fibrotic and structural tissue changes. Here we review work linking inflammation and the development of work-related MSDs. We also propose a conceptual framework suggesting the potential roles that inflammation may play in these disorders, and how inflammation may contribute to pain, motor dysfunction, and to puzzling psychological symptoms that are often characteristic of patients with work-related MSDs.

MANUAL: WASTEWATER TREATMENT DISPOSAL FOR SMALL COMMUNITIES

EPA Science Inventory

Over the past decade, changes in federal policies have forced states to play a larger role in financing and admin- istering public works programs and compelled local governments to do more for themselves. A 1990 report by the U.S. Congress, Office of Technology Assessment i...

Money in the Bank. Lessons Learned from Past Counterinsurgency (COIN) Operations

DTIC Science & Technology

2007-01-01

to work among their own people, which helped draw recruits from established social networks, exploited their familiarity with the villagers and the...in U.S. military support. Local indigenous forces were used to attack the VCI because they were familiar with the terrain and the inhabitants of the...cultivate human intelligence (HUMINT) through a cache of local assets and agents. Direct familiarity with the villagers can help soldiers detect the

Acoustic radiation force impulse (ARFI) imaging: Characterizing the mechanical properties of tissues using their transient response to localized force

NASA Astrophysics Data System (ADS)

Nightingale, Kathryn R.; Palmeri, Mark L.; Congdon, Amy N.; Frinkely, Kristin D.; Trahey, Gregg E.

2004-05-01

Acoustic radiation force impulse (ARFI) imaging utilizes brief, high energy, focused acoustic pulses to generate radiation force in tissue, and conventional diagnostic ultrasound methods to detect the resulting tissue displacements in order to image the relative mechanical properties of tissue. The magnitude and spatial extent of the applied force is dependent upon the transmit beam parameters and the tissue attenuation. Forcing volumes are on the order of 5 mm3, pulse durations are less than 1 ms, and tissue displacements are typically several microns. Images of tissue displacement reflect local tissue stiffness, with softer tissues (e.g., fat) displacing farther than stiffer tissues (e.g., muscle). Parametric images of maximum displacement, time to peak displacement, and recovery time provide information about tissue material properties and structure. In both in vivo and ex vivo data, structures shown in matched B-mode images are in good agreement with those shown in ARFI images, with comparable resolution. Potential clinical applications under investigation include soft tissue lesion characterization, assessment of focal atherosclerosis, and imaging of thermal lesion formation during tissue ablation procedures. Results from ongoing studies will be presented. [Work supported by NIH Grant R01 EB002132-03, and the Whitaker Foundation. System support from Siemens Medical Solutions USA, Inc.

Analog and numerical experiments investigating force chain influences on bed conditions in granular flows

NASA Astrophysics Data System (ADS)

Estep, J.; Dufek, J.

2013-12-01

Granular flows are fundamental processes in several terrestrial and planetary natural events; including surficial flows on volcanic edifices, debris flows, landslides, dune formation, rock falls, sector collapses, and avalanches. Often granular flows can be two-phase, whereby interstitial fluids occupy void space within the particulates. The mobility of granular flows has received significant attention, however the physics that govern their internal behavior remain poorly understood. Here we extend upon previous research showing that force chains can transmit extreme localized forces to the substrates of free surface granular flows, and we combine experimental and computational approaches to further investigate the forces at the bed of simplified granular flows. Analog experiments resolve discrete bed forces via a photoelastic technique, while numerical experiments validate laboratory tests using discrete element model (DEM) simulations. The current work investigates (1) the role of distributed grain sizes on force transmission via force chains, and (2) how the inclusion of interstitial fluids effects force chain development. We also include 3D numerical simulations to apply observed 2D characteristics into real world perspective, and ascertain if the added dimension alters force chain behavior. Previous research showed that bed forces generated by force chain structures can transiently greatly exceed (by several 100%) the bed forces predicted from continuum approaches, and that natural materials are more prone to excessive bed forces than photoelastic materials due to their larger contact stiffnesses. This work suggests that force chain activity may play an important role in the bed physics of dense granular flows by influencing substrate entrainment. Photoelastic experiment image showing force chains in gravity driven granular flow.

Gravitational self-force on generic bound geodesics in Kerr spacetime

NASA Astrophysics Data System (ADS)

van de Meent, Maarten

2018-05-01

In this work we present the first calculation of the gravitational self-force on generic bound geodesics in Kerr spacetime to first order in the mass ratio. That is, the local correction to equations of motion for a compact object orbiting a larger rotating black hole due to its own impact on the gravitational field. This includes both dissipative and conservative effects. Our method builds on and extends earlier methods for calculating the gravitational self-force on equatorial orbits. In particular we reconstruct the local metric perturbation in the outgoing radiation gauge from the Weyl scalar ψ4 , which in turn is obtained by solving the Teukolsky equation using semianalytical frequency domain methods. The gravitational self-force is subsequently obtained using (spherical) l -mode regularization. We test our implementation by comparing the large l -behavior against the analytically known regularization parameters. In addition we validate our results by comparing the long-term average changes to the energy, angular momentum, and Carter constant to changes to these constants of motion inferred from the gravitational wave flux to infinity and down the horizon.

Working with/against Globalization in Education.

ERIC Educational Resources Information Center

Henry, Miriam; Lingard, Bob; Rizvi, Fazal; Taylor, Sandra

1999-01-01

Argues against the juggernaut view of globalization, suggesting that much depends on how we engage with global forces to mitigate their worst consequences and use them to advantage. Views democratic nation-building, informed by education, as pivotal to the engagement process. Locally, educators must retrieve the "public" in public…

Performance evaluation of a six-axis generalized force-reflecting teleoperator

NASA Technical Reports Server (NTRS)

Hannaford, B.; Wood, L.; Guggisberg, B.; Mcaffee, D.; Zak, H.

1989-01-01

Work in real-time distributed computation and control has culminated in a prototype force-reflecting telemanipulation system having a dissimilar master (cable-driven, force-reflecting hand controller) and a slave (PUMA 560 robot with custom controller), an extremely high sampling rate (1000 Hz), and a low loop computation delay (5 msec). In a series of experiments with this system and five trained test operators covering over 100 hours of teleoperation, performance was measured in a series of generic and application-driven tasks with and without force feedback, and with control shared between teleoperation and local sensor referenced control. Measurements defining task performance included 100-Hz recording of six-axis force/torque information from the slave manipulator wrist, task completion time, and visual observation of predefined task errors. The task consisted of high precision peg-in-hole insertion, electrical connectors, velcro attach-de-attach, and a twist-lock multi-pin connector. Each task was repeated three times under several operating conditions: normal bilateral telemanipulation, forward position control without force feedback, and shared control. In shared control, orientation was locally servo controlled to comply with applied torques, while translation was under operator control. All performance measures improved as capability was added along a spectrum of capabilities ranging from pure position control through force-reflecting teleoperation and shared control. Performance was optimal for the bare-handed operator.

Conditions for Destabilizing Pickering emulsions using external electric fields

NASA Astrophysics Data System (ADS)

Hwang, Kyuho; Singh, Pushpendra; Aubry, Nadine

2009-11-01

Fine particles are readily adsorbed at fluid-fluid interfaces, and can be used as stabilizers in emulsion technology by preventing adjacent drops from coalescing with each other. We investigate a new technique to destabilize such emulsions, or Pickering emulsions, by applying an external electric field. Experiments show that the latter has two effects: (i) the drops elongate in the direction of the electric field, (ii) the local particle density varies on the drop surface due to the dielectrophoretic (DEP) force acting on the particles. It is shown that the latter is the dominant factor in the destabilization process. Particularly, the success of the method depends on the values of certain dimensionless parameters; specifically, the ratio of the work done by the dielectrophoretic force must be larger than the work done by the buoyant force. Moreover, drops do not coalesce through the regions where the particles locally cluster, whether those are gathered at the poles or at the equator of the drops. As particles move, particle-free openings form on the drop's surface, which allow for adjacent drops to merge. This process takes place even if the particles are fully packed on the drops' surfaces as particles get ejected from the clustering areas due to a buckling phenomenon.

Catenaries in Drag

NASA Astrophysics Data System (ADS)

Chakrabarti, Brato; Hanna, James

2014-11-01

Dynamical equilibria of towed cables and sedimenting filaments have been the targets of much numerical work; here, we provide analytical expressions for the configurations of a translating and axially moving string subjected to a uniform body force and local, linear, anisotropic drag forces. Generically, these configurations comprise a five-parameter family of planar shapes determined by the ratio of tangential (axial) and normal drag coefficients, the angle between the translational velocity and the body force, the relative magnitudes of translational and axial drag forces with respect to the body force, and a scaling parameter. This five-parameter family of shapes is, in fact, a degenerate six-parameter family of equilibria in which inertial forces rescale the tension in the string without affecting its shape. Each configuration is represented by a first order dynamical system for the tangential angle of the body. Limiting cases include the dynamic catenaries with or without drag, and purely sedimenting or towed strings.

A Study of the Feasibility of Vocational Modules.

ERIC Educational Resources Information Center

Platero, Dillon; And Others

Educational consultants, town residents, Navajo tribal chapters and councils, the Bureau of Indian Affairs, the Navajo Division of Education, and local public school districts in Navajo, New Mexico, worked together to design an effective vocational program for an unskilled labor force sparsely settled within a large geographic area. The concept of…

Electronic Revolution on Main Street.

ERIC Educational Resources Information Center

Schwartz, Gail Garfield

1986-01-01

The electronics revolution is changing way work is done and description of available jobs, shifting some jobs from office to home, and offering new communication services. Technology's impact on central business districts (CBDs) will depend on broad economic forces, but its effects on CBDs as business locations will be conditioned by local real…

Assessing Job Applicants for Skills To Keep the Automotive Industry Competitive.

ERIC Educational Resources Information Center

Advanced Integrated Manufacturing Center, Dayton, OH.

The Advanced Integrated Manufacturing (AIM) Center is a partnership between Sinclair Community College and the University of Dayton (Ohio) that was established to help local manufacturing companies achieve world-class performance by improving their business practices, selecting/developing a highly skilled work force, and making appropriate use of…

[The effect of new industries on changes in population].

PubMed

Meng, C; Zou, N

1985-05-29

Since 1978, China's Qionggang township (population, 8023; area, 3 sq. km), traditionally a fishing village on Jiangsu province's Huanghai coast, has been investing its local capital in an effort to establish several industrial enterprises including its own full-time local labor force. Currently, the rapidly expanding factory work force exceeds the number of fishermen. In addition to providing a statistically detailed chronology of the socioeconomic transition from a small fishing settlement to a rapidly growing industrial town, free-time activities, educational pursuits, and life styles of the newly formed labor force are discussed. From 1981 to 1983, Qionggang's industrial sector produced 4 metal vessels which were delivered directly to the town's fishing sector. With the town's newly generated economic wealth, commercial and public service facilities (i.e., a hospital, a kindergarten, several stores, a bank, and a credit union) have emerged. The economic development of Qionggang township has inspired other rural villages to clear and develop nearby land for similar industrial growth.

Nonstandard Logistics Success in Unconventional Warfare

DTIC Science & Technology

2015-11-01

water from local farms , vendors, and markets. The PACE plan would be con- stantly updated as the operational picture changes, such as a variation in...sus- tainability. For example, if a forward element is purchasing a noticeable amount of rice from a local farm , the team might begin purchasing rice...another OE be forced to use another item that has value. Cash may work in a city center, but a goat in a rural area is just as valuable and easily sold

Does temperature nudging overwhelm aerosol radiative effects in regional integrated climate models?

NASA Astrophysics Data System (ADS)

He, Jian; Glotfelty, Timothy; Yahya, Khairunnisa; Alapaty, Kiran; Yu, Shaocai

2017-04-01

Nudging (data assimilation) is used in many regional integrated meteorology-air quality models to reduce biases in simulated climatology. However, in such modeling systems, temperature changes due to nudging could compete with temperature changes induced by radiatively active and hygroscopic short-lived tracers leading to two interesting dilemmas: when nudging is continuously applied, what are the relative sizes of these two radiative forces at regional and local scales? How do these two forces present in the free atmosphere differ from those present at the surface? This work studies these two issues by converting temperature changes due to nudging into pseudo radiative effects (PRE) at the surface (PRE_sfc), in troposphere (PRE_atm), and at the top of atmosphere (PRE_toa), and comparing PRE with the reported aerosol radiative effects (ARE). Results show that the domain-averaged PRE_sfc is smaller than ARE_sfc estimated in previous studies and this work, but could be significantly larger than ARE_sfc at local scales. PRE_atm is also much smaller than ARE_atm. These results indicate that appropriate nudging methodology could be applied to the integrated models to study aerosol radiative effects at continental/regional scales, but it should be treated with caution for local scale applications.

On the use of SPM to probe the interplay between polymer surface chemistry and polymer surface mechanics

NASA Astrophysics Data System (ADS)

Brogly, Maurice; Noel, Olivier; Awada, Houssein; Castelein, Gilles

2007-03-01

Adhesive properties of a polymer surface results from the complex contribution of surface chemistry and activation of sliding and dissipating mechanisms within the polymer surface layer. The purpose of this study is to dissociate the different contributions (chemical and mechanical) included in an AFM force-distance curve in order to establish relationships between the surface viscoelastic properties of the polymer, the surface chemistry of functionalized polymer surfaces and the adhesive forces, as determined by C-AFM experiments. Indeed we are interested in the measurements of local attractive or adhesive forces in AFM contact mode, of controlled chemical and mechanical model substrates. In order to investigate the interplay between mechanical or viscoelastic mechanisms and surface chemistry during the tip - polymer contact, we achieved force measurements on model PDMS polymer networks, whose surfaces are chemically controlled with the same functional groups as before (silicon substrates). On the basis of AFM nano-indentation experiments, surface Young moduli have been determined. The results show that the viscoelastic contribution is dominating in the adhesion force measurement. We propose an original model, which express the local adhesion force to the energy dissipated within the contact and the surface properties of the material (thermodynamic work of adhesion). Moreover we show that the dissipation function is related to Mc, the mass between crosslinks of the network.

Bedford County Employer Needs Assessment.

ERIC Educational Resources Information Center

Rephann, Terance J.

In the summer of 1995, 371 establishments in Bedford County, Pennsylvania, were surveyed regarding their opinions of the quality of the local work force. The purpose of the study was to provide evaluation data for planning and curriculum development at the secondary and post-secondary school levels. Forty-three percent of the employers responded.…

The Reopening of the Frontier.

ERIC Educational Resources Information Center

Margolis, Jon

1995-01-01

In five Great Plains states, more counties have fewer than six persons per square mile (once a definition of "frontier") than in 1920. Forces of nature and technology have produced fewer farms, resulting in fewer residents and loss of local businesses and schools. Carrington, North Dakota, worked hard to attract a pasta plant, but it may…

After-School as Intermediary Space: Theory and Typology of Partnerships

ERIC Educational Resources Information Center

Noam, Gil G.; Tillinger, Jodi Rosenbaum

2004-01-01

People live in an era of partnering--of joining institutional forces to accomplish complex societal changes. Whether it is the local YMCA that works with a school to serve children during the afterschool hours, a university connecting with its surrounding community, or a city government convening funders and businesses, they are moving into…

Public Service Loan Forgiveness. NASFAA Task Force Report

ERIC Educational Resources Information Center

National Association of Student Financial Aid Administrators, 2014

2014-01-01

The Public Service Loan Forgiveness (PSLF) program was established in 2007 to encourage student borrowers to work in the public sector. Qualifying borrowers may have their Direct Loans forgiven after 10 years of full-time service in an eligible job. Currently, qualifying employers include federal, state, or local government agencies and tax-exempt…

Soviet Political Perspectives on Power Projection.

DTIC Science & Technology

1987-03-01

justified by the recognition on the part of many Soviet economists that the traditional Soviet development model does not work. Rapid nationalization...37 Models of Economic Development................................43 IV. ARMED STRUGGLE AND REVOLUTIONARY CHANGE...Soviets always describe revolutionary change in ~.~ the Third World as merely the product of local social and political forces, part of an inevitable

Regressed relations for forced convection heat transfer in a direct injection stratified charge rotary engine

NASA Technical Reports Server (NTRS)

Lee, Chi M.; Schock, Harold J.

1988-01-01

Currently, the heat transfer equation used in the rotary combustion engine (RCE) simulation model is taken from piston engine studies. These relations have been empirically developed by the experimental input coming from piston engines whose geometry differs considerably from that of the RCE. The objective of this work was to derive equations to estimate heat transfer coefficients in the combustion chamber of an RCE. This was accomplished by making detailed temperature and pressure measurements in a direct injection stratified charge (DISC) RCE under a range of conditions. For each specific measurement point, the local gas velocity was assumed equal to the local rotor tip speed. Local physical properties of the fluids were then calculated. Two types of correlation equations were derived and are described in this paper. The first correlation expresses the Nusselt number as a function of the Prandtl number, Reynolds number, and characteristic temperature ratio; the second correlation expresses the forced convection heat transfer coefficient as a function of fluid temperature, pressure and velocity.

Electromagnetic Radiation Reaction in General Relativity.

NASA Astrophysics Data System (ADS)

O'Donnell, Nuala

Available from UMI in association with The British Library. This thesis examines the electromagnetic radiation reaction felt by a charged body falling freely in an external gravitational field in general relativity. The original objective was to find a new derivation of the radiation reaction force F^{i} of DeWitt and DeWitt^1 which was calculated for the special case of a point charge falling in slow motion in a weak, static gravitational field: F ^{i} = {2over 3}e^2R^{i}_{0j0 }v^{j}. This may be thought of as a local expression since it involves the particle's velocity v^{j } and the local Riemann curvature tensor R ^{i}_{0j0}. Its derivation involves integrals over the whole history of the particle, covering distances of approximately the length scale on which R^{i}_{0j0 } changes. This is different from calculations of the Abraham-Lorentz force of flat space-time involving integrals over distances only a few times the size of the charge. This work was motivated by the wish to find a "local" derivation of the local reaction force. Using Schutz's^2 local initial value method to solve the problem of a charged, rigid, spherically symmetric body moving in an external gravitational field of arbitrary metric. Calculations are done in a Riemann normal coordinate system ^3 and are only valid in a normal neighbourhood of the origin, where geodesics have not begun to cross one another. We solve Maxwell's equations for the self -force by making a slow-motion approximation and keeping terms to first order only in the Riemann tensor and velocity. It is surprising that we find no local radiation reaction. Consider two particles in a static spacetime with the same initial conditions at t = 0. Particle A is that of DeWitt and DeWitt; it feels a reaction force F^{i} = {2over 3}e^2R^{i }_{0j0}v^{j}. Particle B is accelerated from rest to the same small velocity; it feels no reaction force. The two particles therefore follow different trajectories. We conclude that there is a certain amount of history dependence in curved spacetime which is absent in flat spacetime where the Abraham-Lorentz reaction force acts equally on both particles. ftn ^1C. M. DeWitt and B. S. Brehme, Falling Charges, Phys., 1, 3 (1964). ^2B. F. Schutz, Statistical Formulation of Gravitational Radiation Reaction, Phys. Rev. D., 22, 249 (1980). ^3See for example A. Z. Petrov, Einstein Spaces, p.33, Pergamon Press (1969).

Numerical simulation of flows in a circular pipe transversely subjected to a localized impulsive body force with applications to blunt traumatic aortic rupture

NASA Astrophysics Data System (ADS)

Di Labbio, G.; Keshavarz-Motamed, Z.; Kadem, L.

2017-06-01

Much debate surrounds the mechanisms responsible for the occurrence of blunt traumatic aortic rupture in car accidents, particularly on the role of the inertial body force experienced by the blood due to the abrupt deceleration. The isolated influence of such body forces acting on even simple fluid flows is a fundamental problem in fluid dynamics that has not been thoroughly investigated. This study numerically investigates the fundamental physical problem, where the pulsatile flow in a straight circular pipe is subjected to a transverse body force on a localized volume of fluid. The body force is applied as a brief rectangular impulse in three distinct cases, namely during the accelerating, peak, and decelerating phases of the pulsatile flow. A dimensionless number, termed the degree of influence of the body force (Ψ), is devised to quantify the relative strength of the body force over the flow inertia. The impact induces counter-rotating cross-stream vortices at the boundaries of the forced section accompanied by complex secondary flow structures. This secondary flow is found to develop slowest for an impact occurring during an accelerating flow and fastest during a decelerating flow. The peak skewness of the velocity field, however, occurred at successively later times for the three respective cases. After the impact, these secondary flows act to restore the unforced state and such dominant spatial structures are revealed by proper orthogonal decomposition of the velocity field. This work presents a new class of problems that requires further theoretical and experimental investigation.

Labor-Management Cooperation in Illinois: How a Joint Union Company Team Is Improving Facility Safety.

PubMed

Mahan, Bruce; Maclin, Reggie; Ruttenberg, Ruth; Mundy, Keith; Frazee, Tom; Schwartzkopf, Randy; Morawetz, John

2018-01-01

This study of Afton Chemical Corporation's Sauget facility and its International Chemical Workers Union Council (ICWUC) Local 871C demonstrates how significant safety improvements can be made when committed leadership from both management and union work together, build trust, train the entire work force in U.S. Occupational Safety and Health Administration 10-hour classes, and communicate with their work force, both salaried and hourly. A key finding is that listening to the workers closest to production can lead to solutions, many of them more cost-efficient than top-down decision-making. Another is that making safety and health an authentic value is hard work, requiring time, money, and commitment. Third, union and management must both have leadership willing to take chances and learn to trust one another. Fourth, training must be for everyone and ongoing. Finally, health and safety improvements require dedicated funding. The result was resolution of more than one hundred safety concerns and an ongoing institutionalized process for continuing improvement.

Native Competition and Low-Skilled Immigrant Inflows*

PubMed Central

Cadena, Brian C.

2014-01-01

This paper demonstrates that immigration decisions depend on local labor market conditions by documenting the change in low-skilled immigrant inflows in response to supply increases among the US-born. Using pre-reform welfare participation rates as an instrument for changes in native labor supply, I find that immigrants competing with native entrants systematically prefer cities with smaller supply shocks. The extent of the response is substantial: for each native woman working due to reform, 0.5 fewer female immigrants enter the local labor force. These results provide direct evidence that international migration flows tend to equilibrate returns across US local labor markets. PMID:25308997

Identifying the driving forces of urban expansion and its environmental impact in Jakarta-Bandung mega urban region

NASA Astrophysics Data System (ADS)

Pravitasari, A. E.; Rustiadi, E.; Mulya, S. P.; Setiawan, Y.; Fuadina, L. N.; Murtadho, A.

2018-05-01

The socio-economic development in Jakarta-Bandung Mega Urban Region (JBMUR) caused the increasing of urban expansion and led to a variety of environmental damage such as uncontrolled land use conversion and raising anthropogenic disaster. The objectives of this study are: (1) to identify the driving forces of urban expansion that occurs on JBMUR and (2) to analyze the environmental quality decline on JBMUR by producing time series spatial distribution map and spatial autocorrelation of floods and landslide as the proxy of anthropogenic disaster. The driving forces of urban expansion in this study were identified by employing Geographically Weighted Regression (GWR) model using 6 (six) independent variables, namely: population density, percentage of agricultural land, distance to the center of capital city/municipality, percentage of household who works in agricultural sector, distance to the provincial road, and distance to the local road. The GWR results showed that local demographic, social and economic factors including distance to the road spatially affect urban expansion in JBMUR. The time series spatial distribution map of floods and landslide event showed the spatial cluster of anthropogenic disaster in some areas. Through Local Moran Index, we found that environmental damage in one location has a significant impact on the condition of its surrounding area.

The shape dependence of chameleon screening

NASA Astrophysics Data System (ADS)

Burrage, Clare; Copeland, Edmund J.; Moss, Adam; Stevenson, James A.

2018-01-01

Chameleon scalar fields can screen their associated fifth forces from detection by changing their mass with the local density. These models are an archetypal example of a screening mechanism, and have become an important target for both cosmological surveys and terrestrial experiments. In particular there has been much recent interest in searching for chameleon fifth forces in the laboratory. It is known that the chameleon force is less screened around non-spherical sources, but only the field profiles around a few simple shapes are known analytically. In this work we introduce a numerical code that solves for the chameleon field around arbitrary shapes with azimuthal symmetry placed in a spherical vacuum chamber. We find that deviations from spherical symmetry can increase the chameleon acceleration experienced by a test particle, and that the least screened objects are those which minimize some internal dimension. For the shapes considered in this work, keeping the mass, density and background environment fixed, the accelerations due to the source varied by a factor of ~ 3.

Counterinsurgency After Afghanistan: A Concept in Crisis

DTIC Science & Technology

2011-12-01

in strategy was undeniably stabilizing. This also explains the concrete walls, barriers, check- points, and other population-control measures...partnering with Sunni community leaders, Dagger Brigade was able to interpose itself—with concrete barriers, combined outposts, and checkpoints...local forces work together toward the same end. Also important in this regard are the aforementioned check- points, concrete barriers, and other

Educational Choices and the Selection Process: Before and after Compulsory Schooling

ERIC Educational Resources Information Center

Mocetti, Sauro

2012-01-01

The aim of this paper is to analyze the selection process at work before and after compulsory schooling by assessing the determinants of school failures, dropouts, and upper secondary school decisions of young Italians. The data-set is built combining individual data by the Labor Force Survey and aggregate data on local labor markets and school…

Recombination in maize is stable, predictable, and associated with genetic load: a joint study of the US and Chinese maize NAM populations

USDA-ARS?s Scientific Manuscript database

Among the fundamental evolutionary forces, recombination arguably has the largest impact on the practical work of plant breeders. Varying over 1,000-fold across the maize genome, the local meiotic recombination rate limits the resolving power of quantitative trait mapping and the precision of favora...

Diffuse interface models of locally inextensible vesicles in a viscous fluid

PubMed Central

Aland, Sebastian; Egerer, Sabine; Lowengrub, John; Voigt, Axel

2014-01-01

We present a new diffuse interface model for the dynamics of inextensible vesicles in a viscous fluid with inertial forces. A new feature of this work is the implementation of the local inextensibility condition in the diffuse interface context. Local inextensibility is enforced by using a local Lagrange multiplier, which provides the necessary tension force at the interface. We introduce a new equation for the local Lagrange multiplier whose solution essentially provides a harmonic extension of the multiplier off the interface while maintaining the local inextensibility constraint near the interface. We also develop a local relaxation scheme that dynamically corrects local stretching/compression errors thereby preventing their accumulation. Asymptotic analysis is presented that shows that our new system converges to a relaxed version of the inextensible sharp interface model. This is also verified numerically. To solve the equations, we use an adaptive finite element method with implicit coupling between the Navier-Stokes and the diffuse interface inextensibility equations. Numerical simulations of a single vesicle in a shear flow at different Reynolds numbers demonstrate that errors in enforcing local inextensibility may accumulate and lead to large differences in the dynamics in the tumbling regime and smaller differences in the inclination angle of vesicles in the tank-treading regime. The local relaxation algorithm is shown to prevent the accumulation of stretching and compression errors very effectively. Simulations of two vesicles in an extensional flow show that local inextensibility plays an important role when vesicles are in close proximity by inhibiting fluid drainage in the near contact region. PMID:25246712

Phase field crystal simulation of stress induced localized solid-state amorphization in nanocrystalline materials

NASA Astrophysics Data System (ADS)

Xi, Wen; Song, Xiaoqing; Hu, Shi; Chen, Zheng

2017-11-01

In this work, the phase field crystal (PFC) method is used to study the localized solid-state amorphization (SSA) and its dynamic transformation process in polycrystalline materials under the uniaxial tensile deformation with different factors. The impacts of these factors, including strain rates, temperatures and grain sizes, are analyzed. Kinetically, the ultra-high strain rate causes the lattice to be seriously distorted and the grain to gradually collapse, so the dislocation density rises remarkably. Therefore, localized SSA occurs. Thermodynamically, as high temperature increases the activation energy, the atoms are active and prefer to leave the original position, which induce atom rearrangement. Furthermore, small grain size increases the percentage of grain boundary and the interface free energy of the system. As a result, Helmholtz free energy increases. The dislocations and Helmholtz free energy act as the seed and driving force for the process of the localized SSA. Also, the critical diffusion-time step and the percentage of amorphous region areas are calculated. Through this work, the PFC method is proved to be an effective means to study localized SSA under uniaxial tensile deformation.

Phase field crystal simulation of stress induced localized solid-state amorphization in nanocrystalline materials.

PubMed

Xi, Wen; Song, Xiaoqing; Hu, Shi; Chen, Zheng

2017-11-29

In this work, the phase field crystal (PFC) method is used to study the localized solid-state amorphization (SSA) and its dynamic transformation process in polycrystalline materials under the uniaxial tensile deformation with different factors. The impacts of these factors, including strain rates, temperatures and grain sizes, are analyzed. Kinetically, the ultra-high strain rate causes the lattice to be seriously distorted and the grain to gradually collapse, so the dislocation density rises remarkably. Therefore, localized SSA occurs. Thermodynamically, as high temperature increases the activation energy, the atoms are active and prefer to leave the original position, which induce atom rearrangement. Furthermore, small grain size increases the percentage of grain boundary and the interface free energy of the system. As a result, Helmholtz free energy increases. The dislocations and Helmholtz free energy act as the seed and driving force for the process of the localized SSA. Also, the critical diffusion-time step and the percentage of amorphous region areas are calculated. Through this work, the PFC method is proved to be an effective means to study localized SSA under uniaxial tensile deformation.

Hemispheric Transport of Air Pollutants: Issues, Progress, and Implications

NASA Astrophysics Data System (ADS)

Keating, T.

2007-12-01

Once thought of as only a local or regional issue, air quality is now understood to be influenced by local, regional, hemispheric, and global phenomena. There is well-documented evidence from ground-, aircraft-, and satellite- based observations for the intercontinental transport of ozone, aerosols, mercury, and some persistent organic pollutants. Global and regional models have provided a range of estimates of the influence of emissions on one continent on concentrations and deposition levels on another continent. These estimates have been difficult to compare and the significance of this intercontinental influence for the design of air pollution control policies is not well understood. The Task Force on Hemispheric Transport of Air Pollutants organized under the Convention on Long-Range Transboundary Air Pollution is developing the first systematic assessment of intercontinental transport and hemispheric pollution in the Northern Hemisphere. This presentation by one of the co-chairs of the Task Force will explore the motivations behind the creation of the Task Force, review its progress, and discuss the implications of its work for the development of domestic and international air quality management policies.

Reserves in load capacity assessment of existing bridges

NASA Astrophysics Data System (ADS)

Žitný, Jan; Ryjáček, Pavel

2017-09-01

High percentage of all railway bridges in the Czech Republic is made of structural steel. Majority of these bridges is designed according to historical codes and according to the deterioration, they have to be assessed if they satisfy the needs of modern railway traffic. The load capacity assessment of existing bridges according to Eurocodes is however often too conservative and especially, braking and acceleration forces cause huge problems to structural elements of the bridge superstructure. The aim of this paper is to review the different approaches for the determination of braking and acceleration forces. Both, current and historical theoretical models and in-situ measurements are considered. The research of several local European state norms superior to Eurocode for assessment of existing railway bridges shows the big diversity of used local approaches and the conservativeness of Eurocode. This paper should also work as an overview for designers dealing with load capacity assessment, revealing the reserves for existing bridges. Based on these different approaches, theoretical models and data obtained from the measurements, the method for determination of braking and acceleration forces on the basis of real traffic data should be proposed.

The impact of culture clash on deployed troops.

PubMed

Greene, Talya; Buckman, Joshua; Dandeker, Christopher; Greenberg, Neil

2010-12-01

Culture plays a crucial role in the military, helping the armed forces achieve their goals. However, cultural issues can negatively affect personnel's well-being and effectiveness, especially when there is a "clash" between military and other cultures. The literature suggests there should be more training and education on individual service cultures, as well as other countries' military cultures to improve cooperation and coordination during joint operations and working in multinational forces. A greater knowledge of local cultures may help avoid offending noncombatants. When deployment ends, service personnel need more support when they transition back to civilian culture.

The President’s Identity Theft Task Force Report

DTIC Science & Technology

2008-09-01

effeCtIve, RISk-BASed ReSPOnSeS tO dAtA BReACheS SUffeRed By fedeRAl AGenCIeS Issue Data Breach Guidance to Agencies Publish a “Routine Use...and developing a data breach response plan. The FTC will continue to seek opportunities to work with state and local officials and policymakers...of fiscal year 2008. ReCOMMendAtIOn 4: enSURe effeCtIve, RISk-BASed ReSPOnSeS tO dAtA BReACheS SUffeRed By fedeRAl AGenCIeS The Task Force

On the Interaction Between Gravity Waves and Atmospheric Thermal Tides

NASA Astrophysics Data System (ADS)

Agner, Ryan Matthew

Gravity waves and thermal tides are two of the most important dynamical features of the atmosphere. They are both generated in the lower atmosphere and propagate upward transporting energy and momentum to the upper atmosphere. This dissertation focuses on the interaction of these waves in the Mesosphere and Lower Thermosphere (MLT) region of the atmosphere using both observational data and Global Circulation Model (GCMs). The first part of this work focuses on observations of gravity wave interactions with the tides using both LIDAR data at the Star Fire Optical Range (SOR, 35?N, 106.5?W) and a meteor radar data at the Andes LIDAR Observatory (ALO, 30.3?S, 70.7?W). At SOR, the gravity waves are shown to enhance or damp the amplitude of the diurnal variations dependent on altitude while the phase is always delayed. The results compare well with previous mechanistic model results and with the Japanese Atmospheric General circulation model for Upper Atmosphere Research (JAGUAR) high resolution global circulation model. The meteor radar observed the GWs to almost always enhance the tidal amplitudes and either delay or advance the phase depending on the altitude. When compared to previous radar results from the same meteor radar when it was located in Maui, Hawaii, the Chile results are very similar while the LIDAR results show significant differences. This is because of several instrument biases when calculating GW momentum fluxes that is not significant when determining the winds. The radar needs to perform large amounts of all-sky averaging across many weeks, while the LIDAR directly detects waves in a small section of sky. The second part of this work focuses on gravity wave parameterization scheme effects on the tides in GCMs. The Specified Dynamics Whole Atmosphere Community Climate Model (SD-WACCM) and the extended Canadian Middle Atmosphere Model (eCMAM) are used for this analysis. The gravity wave parameterization schemes in the eCMAM (Hines scheme) have been shown to enhance the tidal amplitudes compared to observations while the parameterization scheme in SD-WACCM (Lindzen scheme) overdamps the tides. It is shown here that the Hines scheme assumption that only small scale gravity waves force the atmosphere do not create enough drag to properly constrain the tidal amplitudes. The Lindzen scheme produces too much drag because all wave scales are assumed to be saturated thus continuing to provide forcing on the atmosphere above the breaking altitude. The final part of this work investigates GWs, tides and their interactions on a local time scale instead of a global scale in the two GCMs. The local time GWs in eCMAM are found to have a strong seasonal dependence, with the majority of the forcings at the winter pole at latitudes where the diurnal variations are weak limiting their interactions. In SD-WACCM, the largest local GW forcings are located at mid latitudes near where the diurnal variations peak causing them to dampen the diurnal amplitudes. On a local time level the diurnal variations may be a summation of many tidal modes. The analysis reveals that in eCMAM the DW1 tidal mode is by far the dominant mode accounting for the local time variations. The high amount of modulation of GWs by the DW1 tidal winds does not allow it to be properly constrained, causing it to dominate the local time diurnal variations. Similarly, the DW1 projection of GW forcing is dominant over all other other modes and contributes the most to the local time diurnal GW variations. The local time wind variations in SD-WACCM are in uenced by several tidal modes because the DW1 tide is of compatible amplitudes to other modes. This is because of the increased damping on the tide by the GWs. It is also found that the local GW diurnal variations have significant contributions from all tidal modes due to the time and location of the forcing being dependent only on the tropospheric source regions and not the at altitude tidal winds.

Nanoscale hydrodynamics near solids

NASA Astrophysics Data System (ADS)

Camargo, Diego; de la Torre, J. A.; Duque-Zumajo, D.; Español, Pep; Delgado-Buscalioni, Rafael; Chejne, Farid

2018-02-01

Density Functional Theory (DFT) is a successful and well-established theory for the study of the structure of simple and complex fluids at equilibrium. The theory has been generalized to dynamical situations when the underlying dynamics is diffusive as in, for example, colloidal systems. However, there is no such a clear foundation for Dynamic DFT (DDFT) for the case of simple fluids in contact with solid walls. In this work, we derive DDFT for simple fluids by including not only the mass density field but also the momentum density field of the fluid. The standard projection operator method based on the Kawasaki-Gunton operator is used for deriving the equations for the average value of these fields. The solid is described as featureless under the assumption that all the internal degrees of freedom of the solid relax much faster than those of the fluid (solid elasticity is irrelevant). The fluid moves according to a set of non-local hydrodynamic equations that include explicitly the forces due to the solid. These forces are of two types, reversible forces emerging from the free energy density functional, and accounting for impenetrability of the solid, and irreversible forces that involve the velocity of both the fluid and the solid. These forces are localized in the vicinity of the solid surface. The resulting hydrodynamic equations should allow one to study dynamical regimes of simple fluids in contact with solid objects in isothermal situations.

Ensemble theory for slightly deformable granular matter.

PubMed

Tejada, Ignacio G

2014-09-01

Given a granular system of slightly deformable particles, it is possible to obtain different static and jammed packings subjected to the same macroscopic constraints. These microstates can be compared in a mathematical space defined by the components of the force-moment tensor (i.e. the product of the equivalent stress by the volume of the Voronoi cell). In order to explain the statistical distributions observed there, an athermal ensemble theory can be used. This work proposes a formalism (based on developments of the original theory of Edwards and collaborators) that considers both the internal and the external constraints of the problem. The former give the density of states of the points of this space, and the latter give their statistical weight. The internal constraints are those caused by the intrinsic features of the system (e.g. size distribution, friction, cohesion). They, together with the force-balance condition, determine which the possible local states of equilibrium of a particle are. Under the principle of equal a priori probabilities, and when no other constraints are imposed, it can be assumed that particles are equally likely to be found in any one of these local states of equilibrium. Then a flat sampling over all these local states turns into a non-uniform distribution in the force-moment space that can be represented with density of states functions. Although these functions can be measured, some of their features are explored in this paper. The external constraints are those macroscopic quantities that define the ensemble and are fixed by the protocol. The force-moment, the volume, the elastic potential energy and the stress are some examples of quantities that can be expressed as functions of the force-moment. The associated ensembles are included in the formalism presented here.

Science and Sandy: Lessons Learned

NASA Astrophysics Data System (ADS)

Werner, K.

2013-12-01

Following Hurricane Sandy's impact on the mid-Atlantic region, President Obama established a Task Force to '...ensure that the Federal Government continues to provide appropriate resources to support affected State, local, and tribal communities to improve the region's resilience, health, and prosperity by building for the future.' The author was detailed from NOAA to the Task Force between January and June 2013. As the Task Force and others began to take stock of the region's needs and develop plans to address them, many diverse approaches emerged from different areas of expertise including: infrastructure, management and construction, housing, public health, and others. Decision making in this environment was complex with many interests and variables to consider and balance. Although often relevant, science and technical expertise was not always at the forefront of this process. This talk describes the author's experience with the Sandy Task Force focusing on organizing scientific expertise to support the work of the Task Force. This includes a description of federal activity supporting Sandy recovery efforts, the role of the Task Force, and lessons learned from developing a science support function within the Task Force.

Toward canonical ensemble distribution from self-guided Langevin dynamics simulation

NASA Astrophysics Data System (ADS)

Wu, Xiongwu; Brooks, Bernard R.

2011-04-01

This work derives a quantitative description of the conformational distribution in self-guided Langevin dynamics (SGLD) simulations. SGLD simulations employ guiding forces calculated from local average momentums to enhance low-frequency motion. This enhancement in low-frequency motion dramatically accelerates conformational search efficiency, but also induces certain perturbations in conformational distribution. Through the local averaging, we separate properties of molecular systems into low-frequency and high-frequency portions. The guiding force effect on the conformational distribution is quantitatively described using these low-frequency and high-frequency properties. This quantitative relation provides a way to convert between a canonical ensemble and a self-guided ensemble. Using example systems, we demonstrated how to utilize the relation to obtain canonical ensemble properties and conformational distributions from SGLD simulations. This development makes SGLD not only an efficient approach for conformational searching, but also an accurate means for conformational sampling.

Afghanistan’s Local War: Building Local Defense Forces

DTIC Science & Technology

2010-01-01

Afghanistan’s Local War: Building Local Defense Forces economic and other development conditions. As the Nobel Prize- winning economist Amartya Sen ...strengthen warlords 9 Amartya Sen , Development as Freedom, New York: Anchor Books, 2000, p. 11. Mitigating Risks 77 • weaken central government forces...Taliban Afghanistan, Bonn: Bonn International Center for Conversion, 2002. Sen , Amartya , Development as Freedom, New York: Anchor Books, 2000. Shahrani

US files WTO complaints against Brazil over requirement for "local working" of patents.

PubMed

Elliott, R

2000-01-01

At the end of May 2000, the US (later joined by the European Communities) filed a complaint against Brazil at the World Trade Organization (WTO), alleging Brazil was in violation of its obligations under the Agreement on Trade-Related Aspects of Intellectual Property Rights (the TRIPS Agreement) and the 1994 General Agreement on Tariffs and Trade. Brazilian legislation that came into force in 1997 establishes that, in order to enjoy exclusive patent rights in Brazil, the holder of a patent on an invention must satisfy a "local working" requirement. In other words, the patent holder must "work" the patent in Brazil to enjoy full patent protection. If it fails to do this, the law says it shall be subject to the possibility of the government issuing a compulsory license, allowing someone else to use the invention and pay a royalty fee to the patent holder.

Analytical and Computational Modeling of Mechanical Waves in Microscale Granular Crystals: Nonlinearity and Rotational Dynamics

NASA Astrophysics Data System (ADS)

Wallen, Samuel P.

Granular media are one of the most common, yet least understood forms of matter on earth. The difficulties in understanding the physics of granular media stem from the fact that they are typically heterogeneous and highly disordered, and the grains interact via nonlinear contact forces. Historically, one approach to reducing these complexities and gaining new insight has been the study of granular crystals, which are ordered arrays of similarly-shaped particles (typically spheres) in Hertzian contact. Using this setting, past works explored the rich nonlinear dynamics stemming from contact forces, and proposed avenues where such granular crystals could form designer, dynamically responsive materials, which yield beneficial functionality in dynamic regimes. In recent years, the combination of self-assembly fabrication methods and laser ultrasonic experimental characterization have enabled the study of granular crystals at microscale. While our intuition may suggest that these microscale granular crystals are simply scaled-down versions of their macroscale counterparts, in fact, the relevant physics change drastically; for example, short-range adhesive forces between particles, which are negligible at macroscale, are several orders of magnitude stronger than gravity at microscale. In this thesis, we present recent advances in analytical and computational modeling of microscale granular crystals, in particular concerning the interplay of nonlinearity, shear interactions, and particle rotations, which have previously been either absent, or included separately at macroscale. Drawing inspiration from past works on phononic crystals and nonlinear lattices, we explore problems involving locally-resonant metamaterials, nonlinear localized modes, amplitude-dependent energy partition, and other rich dynamical phenomena. This work enhances our understanding of microscale granular media, which may find applicability in fields such as ultrasonic wave tailoring, signal processing, shock and vibration mitigation, and powder processing.

Return on Investment: A Cost-Effectiveness Measure for the Texas' Workforce System.

ERIC Educational Resources Information Center

Norris, Davy N.; King, Christopher T.

Texas is developing a return-on-investment (ROI) measure to assess the cost-effectiveness of work force programs. Emphasis is on issues related to conducting cross-program ROI analysis at the level of the Local Workforce Development Board (LWDB) in career or one-stop centers. To make the most appropriate and effective use of ROI, the following…

Exploring Taiwanese Preservice Teachers' Identity Construction in the Context of Service-Learning: Conflict and Development

ERIC Educational Resources Information Center

Tseng, Ming-i Lydia

2017-01-01

Language teacher identity (LTI) has gained prominence in second language education in the recent two decades, particularly the complexity of identity construction in the changing context shaped by local and global forces. This study adds to recent work on LTI by exploring how Asian teachers of English as a foreign language (EFL) constructed their…

A Librarian in Every School, Books in Every Home: A Modest Proposal

ERIC Educational Resources Information Center

Peterson, Bob

2010-01-01

This spring, the Milwaukee district announced major cuts to local school budgets for next year. At the 400-student elementary school where the author works, the projected cuts meant that, despite a modest increase in student enrollment, they had to cut an additional staff position. Given that in the past few years budget cuts had forced them to…

Formation control of robotic swarm using bounded artificial forces.

PubMed

Qin, Long; Zha, Yabing; Yin, Quanjun; Peng, Yong

2013-01-01

Formation control of multirobot systems has drawn significant attention in the recent years. This paper presents a potential field control algorithm, navigating a swarm of robots into a predefined 2D shape while avoiding intermember collisions. The algorithm applies in both stationary and moving targets formation. We define the bounded artificial forces in the form of exponential functions, so that the behavior of the swarm drove by the forces can be adjusted via selecting proper control parameters. The theoretical analysis of the swarm behavior proves the stability and convergence properties of the algorithm. We further make certain modifications upon the forces to improve the robustness of the swarm behavior in the presence of realistic implementation considerations. The considerations include obstacle avoidance, local minima, and deformation of the shape. Finally, detailed simulation results validate the efficiency of the proposed algorithm, and the direction of possible futrue work is discussed in the conclusions.

Formation Control of Robotic Swarm Using Bounded Artificial Forces

PubMed Central

Zha, Yabing; Peng, Yong

2013-01-01

Formation control of multirobot systems has drawn significant attention in the recent years. This paper presents a potential field control algorithm, navigating a swarm of robots into a predefined 2D shape while avoiding intermember collisions. The algorithm applies in both stationary and moving targets formation. We define the bounded artificial forces in the form of exponential functions, so that the behavior of the swarm drove by the forces can be adjusted via selecting proper control parameters. The theoretical analysis of the swarm behavior proves the stability and convergence properties of the algorithm. We further make certain modifications upon the forces to improve the robustness of the swarm behavior in the presence of realistic implementation considerations. The considerations include obstacle avoidance, local minima, and deformation of the shape. Finally, detailed simulation results validate the efficiency of the proposed algorithm, and the direction of possible futrue work is discussed in the conclusions. PMID:24453809

Modelling of deformation process for the layer of elastoviscoplastic media under surface action of periodic force of arbitrary type

NASA Astrophysics Data System (ADS)

Mikheyev, V. V.; Saveliev, S. V.

2018-01-01

Description of deflected mode for different types of materials under action of external force plays special role for wide variety of applications - from construction mechanics to circuits engineering. This article con-siders the problem of plastic deformation of the layer of elastoviscolastic soil under surface periodic force. The problem was solved with use of the modified lumped parameters approach which takes into account close to real distribution of normal stress in the depth of the layer along with changes in local mechanical properties of the material taking place during plastic deformation. Special numeric algorithm was worked out for computer modeling of the process. As an example of application suggested algorithm was realized for the deformation of the layer of elasoviscoplastic material by the source of external lateral force with the parameters of real technological process of soil compaction.

Learning soft skills the hard way: Historiographical considerations on the cultural adjustment process of German-speaking émigré neuroscientists in Canada, 1933 to 1963.

PubMed

Stahnisch, Frank W

2016-01-01

This article is a historiographical exploration of the special forms of knowledge generation and knowledge transmission that occur along local cultural boundaries in the modern neurosciences. Following the inauguration of the so-called "Law on the Re-Establishment of a Professional Civil Service" in Nazi Germany on April 7, 1933, hundreds of Jewish and oppositional neurologists, neuropathologists, and psychiatrists were forced out of their academic positions, having to leave their home countries and local knowledge economies and traditions for Canada and the United States. A closer analysis of their living and working conditions will create an understanding of some of the elements and factors that determined the international forced migration waves of physicians and clinical neuroscientists in the twentieth century from a historiographical perspective. While I am particularly looking here at new case examples regarding the forced migration during the National Socialist period in Germany, the analysis follows German-speaking émigré neurologists and psychiatrists who found refuge and settled in Canada. These individuals form an understudied group of refugee medical professionals, despite the fact that the subsegments of refugee neurologists and clinical psychoanalysts in the United States, for example, have been a fairly well-investigated population, as the works of Grob (1983), Lunbeck (1995), or Ash and Soellner (1996) have shown. This article is primarily an exploration of the adjustment and acculturation processes of several highly versatile and well-rounded German-speaking physicians, who had received their prior education in neurology, psychiatry, and basic brain research. They were forced out of their academic home institutions and had to leave their clinical research fields as well as their disciplinary self-understanding behind on the other side of the Atlantic.

Learning soft skills the hard way: Historiographical considerations on the cultural adjustment process of German-speaking émigré neuroscientists in Canada, 1933 to 1963

PubMed Central

Stahnisch, Frank W.

2016-01-01

ABSTRACT This article is a historiographical exploration of the special forms of knowledge generation and knowledge transmission that occur along local cultural boundaries in the modern neurosciences. Following the inauguration of the so-called “Law on the Re-Establishment of a Professional Civil Service” in Nazi Germany on April 7, 1933, hundreds of Jewish and oppositional neurologists, neuropathologists, and psychiatrists were forced out of their academic positions, having to leave their home countries and local knowledge economies and traditions for Canada and the United States. A closer analysis of their living and working conditions will create an understanding of some of the elements and factors that determined the international forced migration waves of physicians and clinical neuroscientists in the twentieth century from a historiographical perspective. While I am particularly looking here at new case examples regarding the forced migration during the National Socialist period in Germany, the analysis follows German-speaking émigré neurologists and psychiatrists who found refuge and settled in Canada. These individuals form an understudied group of refugee medical professionals, despite the fact that the subsegments of refugee neurologists and clinical psychoanalysts in the United States, for example, have been a fairly well-investigated population, as the works of Grob (1983), Lunbeck (1995), or Ash and Soellner (1996) have shown. This article is primarily an exploration of the adjustment and acculturation processes of several highly versatile and well-rounded German-speaking physicians, who had received their prior education in neurology, psychiatry, and basic brain research. They were forced out of their academic home institutions and had to leave their clinical research fields as well as their disciplinary self-understanding behind on the other side of the Atlantic. PMID:26796868

Dynamic response characteristics of dual flow-path integrally bladed rotors

NASA Astrophysics Data System (ADS)

Beck, Joseph A.; Brown, Jeffrey M.; Scott-Emuakpor, Onome E.; Cross, Charles J.; Slater, Joseph C.

2015-02-01

New turbine engine designs requiring secondary flow compression often look to dual flow-path integrally bladed rotors (DFIBRs) since these stages have the ability to perform work on the secondary, or bypassed, flow-field. While analogous to traditional integrally bladed rotor stages, DFIBR designs have many differences that result in unique dynamic response characteristics that must be understood to avoid fatigue. This work investigates these characteristics using reduced-order models (ROMs) that incorporate mistuning through perturbations to blade frequencies. This work provides an alternative to computationally intensive geometric-mistuning approaches for DFIBRs by utilizing tuned blade mode reductions and substructure coupling in cyclic coordinates. Free and forced response results are compared to full finite element model (FEM) solutions to determine if any errors are related to the reduced-order model formulation reduction methods. It is shown that DFIBRs have many more frequency veering regions than their single flow-path integrally blade rotor (IBR) counterparts. Modal families are shown to transition between system, inner-blade, and outer-blade motion. Furthermore, findings illustrate that while mode localization of traditional IBRs is limited to a single or small subset of blades, DFIBRs can have modal energy localized to either an inner- or outer-blade set resulting in many blades responding above tuned levels. Lastly, ROM forced response predictions compare well to full FEM predictions for the two test cases shown.

Directed assembly of hybrid nanostructures using optically resonant nanotweezers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Erickson, David

This represents the final report for this project. Over the course of the project we have made significant progress in photonically driven nano-assembly including: (1) demonstrating the first direct optical tweezer based manipulation of proteins, (2) the ability to apply optical angular torques to microtubuals and other rod-shaped microparticles, (3) direct assembly of hybrid nanostructures comprising of polymeric nanoparticles and carbon nanotubes and, (4) the ability to drive biological reactions (specifically protein aggregation) that are thermodynamically unfavorable by applying localized optical work. These advancements are described in the list of papers provided in section 2.0 of the below. Summary detailsmore » are provided in prior year annual reports. We have two additional papers which will be submitted shortly based on the work done under this award. An updated publication list will be provided to the program manager when those are accepted. In this report, we report on a new advancement made in the final project year, which uses the nanotweezer technology to perform direct measurements of particle-surface interactions. Briefly, these measurements are important for characterizing the stability and behavior of colloidal and nanoparticle suspensions and current techniques are limited in their ability to measure piconewton scale interaction forces on sub-micrometer particles due to signal detection limits and thermal noise. In this project year we developed a new technique called “Nanophotonic Force Microscopy” which uses the localized region of exponentially decaying, near-field, light to confine small particles close to a surface. From the statistical distribution of the light intensity scattered by the particle the technique maps out the potential well of the trap and directly quantify the repulsive force between the nanoparticle and the surface. The major advantage of the technique is that it can measure forces and energy wells below the thermal noise limit, resolving interaction forces smaller than 1 pN on dielectric particles as small as 100 nm in diameter.« less

True non-contact atomic force microscopy imaging of heterogeneous biological samples in liquids: topography and material contrast.

PubMed

Almonte, Lisa; Colchero, Jaime

2017-02-23

The present work analyses how the tip-sample interaction signals critically determine the operation of an Atomic Force Microscope (AFM) set-up immersed in liquid. On heterogeneous samples, the conservative tip-sample interaction may vary significantly from point to point - in particular from attractive to repulsive - rendering correct feedback very challenging. Lipid membranes prepared on a mica substrate are analyzed as reference samples which are locally heterogeneous (material contrast). The AFM set-up is operated dynamically at low oscillation amplitude and all available experimental data signals - the normal force, as well as the amplitude and frequency - are recorded simultaneously. From the analysis of how the dissipation (oscillation amplitude) and the conservative interaction (normal force and resonance frequency) vary with the tip-sample distance we conclude that dissipation is the only appropriate feedback source for stable and correct topographic imaging. The normal force and phase then carry information about the sample composition ("chemical contrast"). Dynamic AFM allows imaging in a non-contact regime where essentially no forces are applied, rendering dynamic AFM a truly non-invasive technique.

Low-resistive penetration in granular media

NASA Astrophysics Data System (ADS)

Darbois Texier, Baptiste; Ibarra, Alejandro; Melo, Fransisco

The quasi-static immersion of an intruder into a granular assembly requires a force that is several orders of magnitude larger than necessary in fluids under similar conditions. This occurs as a result of the progressive formation of a network composed of force chains, which simultaneously increase in size with intruder penetration. The present work shows that the resisting force for the immersion of an intruder into a granular material can be reduced by an order of magnitude with mechanical vibrations of small amplitude (A = 10 μm) and low frequency (f = 50-200 Hz). The effect of the vibrations characteristics and the intruder geometry on the drop of the resistive force were inspected experimentally. Thanks to flow visualizations, it has been shown that vibrations induce a local convection into the granular media leading to the modification of the network of force chains. Moreover, scaling arguments are developed in order to rationalize our observations and to predict under which circumstances the resistive force is reduced. Finally, the use of such a phenomenon in the animal kingdom and the technological world will be discussed.

Common Core and the Uncommon Learner: How Autism Affects Acquisition of Common Core State Standards

ERIC Educational Resources Information Center

Marsh, Wendela Whitcomb

2015-01-01

The Common Core State Standards (CCSS 2014a, b) are here to stay. State and local education agencies are responsible for ensuring that schools teach all students the core standards that they will need in college and the work force. However, the ever-growing population of students on the autism spectrum has unique learning needs which may make it…

Why High-Order Polynomials Should Not Be Used in Regression Discontinuity Designs. NBER Working Paper No. 20405

ERIC Educational Resources Information Center

Gelman, Andrew; Imbens, Guido

2014-01-01

It is common in regression discontinuity analysis to control for high order (third, fourth, or higher) polynomials of the forcing variable. We argue that estimators for causal effects based on such methods can be misleading, and we recommend researchers do not use them, and instead use estimators based on local linear or quadratic polynomials or…

17,000 Islands, One Goal: Indonesia Turns to Online Resources to Create a Network of School-Based Coaches

ERIC Educational Resources Information Center

Burns, Mary

2010-01-01

Community has taken on a new meaning for several school-based coaches spread across Indonesia. For far too long in developing countries, educators have been forced to rely on one-shot centralized professional development for teachers and those who work with them. A shortage of money, locally trained staff, and access to learning materials has made…

Force reduction induced by unidirectional transversal muscle loading is independent of local pressure.

PubMed

Siebert, Tobias; Rode, Christian; Till, Olaf; Stutzig, Norman; Blickhan, Reinhard

2016-05-03

Transversal unidirectional compression applied to muscles via external loading affects muscle contraction dynamics in the longitudinal direction. A recent study reported decreasing longitudinal muscle forces with increasing transversal load applied with a constant contact area (i.e., leading to a simultaneous increase in local pressure). To shed light on these results, we examine whether the decrease in longitudinal force depends on the load, the local pressure, or both. To this end, we perform isometric experiments on rat M. gastrocnemius medialis without and with transversal loading (i) changing the local pressure from 1.1-3.2Ncm(-2) (n=9) at a constant transversal load (1.62N) and (ii) increasing the transversal load (1.15-3.45N) at a constant local pressure of 2.3Ncm(-2) (n=7). While we did not note changes in the decrease in longitudinal muscle force in the first experiment, the second experiment resulted in an almost-linear reduction of longitudinal force between 7.5±0.6% and 14.1±1.7%. We conclude that the observed longitudinal force reduction is not induced by local effects such as malfunction of single muscle compartments, but that similar internal stress conditions and myofilament configurations occur when the local pressure changes given a constant load. The decreased longitudinal force may be explained by increased internal pressure and a deformed myofilament lattice that is likely associated with the decomposition of cross-bridge forces on the one hand and the inhibition of cross-bridges on the other hand. Copyright © 2016 Elsevier Ltd. All rights reserved.

Applying Best Practices to Florida Local Government Retrofit Programs

DOE Office of Scientific and Technical Information (OSTI.GOV)

McIlvaine, J.; Sutherland, K.

In some communities, local government and non-profit entities have funds to purchase and renovate distressed, foreclosed homes for resale in the affordable housing market. Numerous opportunities to improve whole house energy efficiency are inherent in these comprehensive renovations. BA-PIRC worked together in a multi-year field study making recommendations in individual homes, meanwhile compiling improvement costs, projected energy savings, practical challenges, and labor force factors surrounding common energy-related renovation measures. The field study, Phase 1 of this research, resulted in a set of best practices appropriate to the current labor pool and market conditions in central Florida to achieve projected annualmore » energy savings of 15-30% and higher. This report describes Phase 2 of the work where researchers worked with a local government partner to implement and refine the 'current best practices.' A simulation study was conducted to characterize savings potential under three sets of conditions representing varying replacement needs for energy-related equipment and envelope components. The three scenarios apply readily to the general remodeling industry as for renovation of foreclosed homes for the affordable housing market. Our new local government partner, the City of Melbourne, implemented the best practices in a community-scale renovation program that included ten homes in 2012.« less

Existing Whole-House Solutions Case Study: Applying Best Practices to Florida Local Government Retrofit Programs - Central Florida

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

In some communities, local government and non-profit entities have funds to purchase and renovate distressed, foreclosed homes for resale in the affordable housing market. Numerous opportunities to improve whole house energy efficiency are inherent in these comprehensive renovations. BA-PIRC worked together in a multiyear field study making recommendations in individual homes, meanwhile compiling improvement costs, projected energy savings, practical challenges, and labor force factors surrounding common energy-related renovation measures. The field study, Phase 1 of this research, resulted in a set of best practices appropriate to the current labor pool and market conditions in central Florida to achieve projected annualmore » energy savings of 15%-30% and higher. This case study describes Phase 2 of the work where researchers worked with a local government partner to implement and refine the "current best practices". A simulation study was conducted to characterize savings potential under three sets of conditions representing varying replacement needs for energy-related equipment and envelope components. The three scenarios apply readily to the general remodeling industry as for renovation of foreclosed homes for the affordable housing market. The new local government partner, the City of Melbourne, implemented the best practices in a community-scale renovation program that included ten homes in 2012.« less

Applying Best Practices to Florida Local Government Retrofit Programs, Central Florida (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

In some communities, local government and non-profit entities have funds to purchase and renovate distressed, foreclosed homes for resale in the affordable housing market. Numerous opportunities to improve whole house energy efficiency are inherent in these comprehensive renovations. BA-PIRC worked together in a multi-year field study making recommendations in individual homes, meanwhile compiling improvement costs, projected energy savings, practical challenges, and labor force factors surrounding common energy-related renovation measures. The field study, Phase 1 of this research, resulted in a set of best practices appropriate to the current labor pool and market conditions in central Florida to achieve projected annualmore » energy savings of 15-30% and higher. This report describes Phase 2 of the work where researchers worked with a local government partner to implement and refine the "current best practices". A simulation study was conducted to characterize savings potential under three sets of conditions representing varying replacement needs for energy-related equipment and envelope components. The three scenarios apply readily to the general remodeling industry as for renovation of foreclosed homes for the affordable housing market. Our new local government partner, the City of Melbourne, implemented the best practices in a community-scale renovation program that included ten homes in 2012.« less

Applying Best Practices to Florida Local Government Retrofit Programs

DOE Office of Scientific and Technical Information (OSTI.GOV)

McIlvaine, J.; Sutherland, K.

In some communities, local government and non-profit entities have funds to purchase and renovate distressed, foreclosed homes for resale in the affordable housing market. Numerous opportunities to improve whole house energy efficiency are inherent in these comprehensive renovations. BA-PIRC worked together in a multiyear field study making recommendations in individual homes, meanwhile compiling improvement costs, projected energy savings, practical challenges, and labor force factors surrounding common energy-related renovation measures. The field study, Phase 1 of this research, resulted in a set of best practices appropriate to the current labor pool and market conditions in central Florida to achieve projected annualmore » energy savings of 15%-30% and higher. This report describes Phase 2 of the work where researchers worked with a local government partner to implement and refine the "current best practices". A simulation study was conducted to characterize savings potential under three sets of conditions representing varying replacement needs for energy-related equipment and envelope components. The three scenarios apply readily to the general remodeling industry as for renovation of foreclosed homes for the affordable housing market. The new local government partner, the City of Melbourne, implemented the best practices in a community-scale renovation program that included ten homes in 2012.« less

Towards a unified description of the charge transport mechanisms in conductive atomic force microscopy studies of semiconducting polymers.

PubMed

Moerman, D; Sebaihi, N; Kaviyil, S E; Leclère, P; Lazzaroni, R; Douhéret, O

2014-09-21

In this work, conductive atomic force microscopy (C-AFM) is used to study the local electrical properties in thin films of self-organized fibrillate poly(3-hexylthiophene) (P3HT), as a reference polymer semiconductor. Depending on the geometrical confinement in the transport channel, the C-AFM current is shown to be governed either by the charge transport in the film or by the carrier injection at the tip-sample contact, leading to either bulk or local electrical characterization of the semiconducting polymer, respectively. Local I-V profiles allow discrimination of the different dominating electrical mechanisms, i.e., resistive in the transport regime and space charge limited current (SCLC) in the local regime. A modified Mott-Gurney law is analytically derived for the contact regime, taking into account the point-probe geometry of the contact and the radial injection of carriers. Within the SCLC regime, the probed depth is shown to remain below 12 nm with a lateral electrical resolution below 5 nm. This confirms that high resolution is reached in those C-AFM measurements, which therefore allows for the analysis of single organic semiconducting nanostructures. The carrier density and mobility in the volume probed under the tip under steady-state conditions are also determined in the SCLC regime.

Wave propagation and power flow in an acoustic metamaterial plate with lateral local resonance attachment

NASA Astrophysics Data System (ADS)

Wang, Ting; Sheng, Meiping; Ding, Xiaodong; Yan, Xiaowei

2018-03-01

This paper presents analysis on wave propagation and power flow in an acoustic metamaterial plate with lateral local resonance. The metamaterial is designed to have lateral local resonance systems attached to a homogeneous plate. Relevant theoretical analysis, numerical modelling and application prospect are presented. Results show that the metamaterial has two complete band gaps for flexural wave absorption and vibration attenuation. Damping can smooth and lower the metamaterial’s frequency responses in high frequency ranges at the expense of the band gap effect, and as an important factor to calculate the power flow is thoroughly investigated. Moreover, the effective mass density becomes negative and unbounded at specific frequencies. Simultaneously, power flow within band gaps are dramatically blocked from the power flow contour and power flow maps. Results from finite element modelling and power flow analysis reveal the working mechanism of the flexural wave attenuation and power flow blocked within the band gaps, where part of the flexural vibration is absorbed by the vertical resonator and the rest is transformed through four-link-mechanisms to the lateral resonators that oscillate and generate inertial forces indirectly to counterbalance the shear forces induced by the vibrational plate. The power flow is stored in the vertical and lateral local resonance, as well as in the connected plate.

Time-local equation for exact time-dependent optimized effective potential in time-dependent density functional theory

NASA Astrophysics Data System (ADS)

Liao, Sheng-Lun; Ho, Tak-San; Rabitz, Herschel; Chu, Shih-I.

2017-04-01

Solving and analyzing the exact time-dependent optimized effective potential (TDOEP) integral equation has been a longstanding challenge due to its highly nonlinear and nonlocal nature. To meet the challenge, we derive an exact time-local TDOEP equation that admits a unique real-time solution in terms of time-dependent Kohn-Sham orbitals and effective memory orbitals. For illustration, the dipole evolution dynamics of a one-dimension-model chain of hydrogen atoms is numerically evaluated and examined to demonstrate the utility of the proposed time-local formulation. Importantly, it is shown that the zero-force theorem, violated by the time-dependent Krieger-Li-Iafrate approximation, is fulfilled in the current TDOEP framework. This work was partially supported by DOE.

Fractionation of Magnetic Microspheres in a Microfluidic Spiral: Interplay between Magnetic and Hydrodynamic Forces

PubMed Central

Hayden, M. E.; Häfeli, U. O.

2017-01-01

Magnetic forces and curvature-induced hydrodynamic drag have both been studied and employed in continuous microfluidic particle separation and enrichment schemes. Here we combine the two. We investigate consequences of applying an outwardly directed magnetic force to a dilute suspension of magnetic microspheres circulating in a spiral microfluidic channel. This force is realized with an array of permanent magnets arranged to produce a magnetic field with octupolar symmetry about the spiral axis. At low flow rates particles cluster around an apparent streamline of the flow near the outer wall of the turn. At high flow rates this equilibrium is disrupted by the induced secondary (Dean) flow and a new equilibrium is established near the inner wall of the turn. A model incorporating key forces involved in establishing these equilibria is described, and is used to extract quantitative information about the magnitude of local Dean drag forces from experimental data. Steady-state fractionation of suspensions by particle size under the combined influence of magnetic and hydrodynamic forces is demonstrated. Extensions of this work could lead to new continuous microscale particle sorting and enrichment processes with improved fidelity and specificity. PMID:28107472

Theory and computation of general force balance in non-axisymmetric tokamak equilibria

NASA Astrophysics Data System (ADS)

Park, Jong-Kyu; Logan, Nikolas; Wang, Zhirui; Kim, Kimin; Boozer, Allen; Liu, Yueqiang; Menard, Jonathan

2014-10-01

Non-axisymmetric equilibria in tokamaks can be effectively described by linearized force balance. In addition to the conventional isotropic pressure force, there are three important components that can strongly contribute to the force balance; rotational, anisotropic tensor pressure, and externally given forces, i.e. ∇ --> p + ρv-> . ∇ --> v-> + ∇ --> . <-->Π + f-> = j-> × B-> , especially in, but not limited to, high β and rotating plasmas. Within the assumption of nested flux surfaces, Maxwell equations and energy minimization lead to the modified-generalized Newcomb equation for radial displacements with simple algebraic relations for perpendicular and parallel displacements, including an inhomogeneous term if any of the forces are not explicitly dependent on displacements. The general perturbed equilibrium code (GPEC) solves this force balance consistent with energy and torque given by external perturbations. Local and global behaviors of solutions will be discussed when ∇ --> . <-->Π is solved by the semi-analytic code PENT and will be compared with MARS-K. Any first-principle transport code calculating ∇ --> . <-->Π or f-> , e.g. POCA, can also be incorporated without demanding iterations. This work was supported by DOE Contract DE-AC02-09CH11466.

Evaluation of mechanical deformation and distributive magnetic loads with different mechanical constraints in two parallel conducting bars

NASA Astrophysics Data System (ADS)

Lee, Ho-Young; Lee, Se-Hee

2017-08-01

Mechanical deformation, bending deformation, and distributive magnetic loads were evaluated numerically and experimentally for conducting materials excited with high current. Until now, many research works have extensively studied the area of magnetic force and mechanical deformation by using coupled approaches such as multiphysics solvers. In coupled analysis for magnetoelastic problems, some articles and commercial software have presented the resultant mechanical deformation and stress on the body. To evaluate the mechanical deformation, the Lorentz force density method (LZ) and the Maxwell stress tensor method (MX) have been widely used for conducting materials. However, it is difficult to find any experimental verification regarding mechanical deformation or bending deformation due to magnetic force density. Therefore, we compared our numerical results to those from experiments with two parallel conducting bars to verify our numerical setup for bending deformation. Before showing this, the basic and interesting coupled simulation was conducted to test the mechanical deformations by the LZ (body force density) and the MX (surface force density) methods. This resulted in MX gave the same total force as LZ, but the local force distribution in MX introduced an incorrect mechanical deformation in the simulation of a solid conductor.

Time-resolved electric force microscopy of charge traps in polycrystalline pentacene films

NASA Astrophysics Data System (ADS)

Jaquith, Michael; Muller, Erik; Marohn, John

2006-03-01

The microscopic mechanisms by which charges trap in organic electronic materials are poorly understood. Muller and Marohn recently showed that electric force microscopy (EFM) can be used to image trapped charge in working pentacene thin-film transistors [E. M. Muller et al, Adv. Mater. 17 1410 (2005)]. We have extended their work by imaging trapped charge in pentacene films with much larger grains. In contrast to the previous study in which charge was found to trap inhomogeneously throughout the transistor gap, we find microscopic evidence for a new trapping mechanism in which charges trap predominantly at the pentacene/metal interface in large-grained devices. We have also made localized measurements of the trap growth over time by performing pulsed-gate EFM experiments. Integrated-rate kinetics data supports a charge trap mechanism which is second order in holes, e.g., holes trap in pairs, although the charge-trapping rate appears to depend on gate voltage.

Development of Three-Dimensional Flow Code Package to Predict Performance and Stability of Aircraft with Leading Edge Ice Contamination

NASA Technical Reports Server (NTRS)

Strash, D. J.; Summa, J. M.

1996-01-01

In the work reported herein, a simplified, uncoupled, zonal procedure is utilized to assess the capability of numerically simulating icing effects on a Boeing 727-200 aircraft. The computational approach combines potential flow plus boundary layer simulations by VSAERO for the un-iced aircraft forces and moments with Navier-Stokes simulations by NPARC for the incremental forces and moments due to iced components. These are compared with wind tunnel force and moment data, supplied by the Boeing Company, examining longitudinal flight characteristics. Grid refinement improved the local flow features over previously reported work with no appreciable difference in the incremental ice effect. The computed lift curve slope with and without empennage ice matches the experimental value to within 1%, and the zero lift angle agrees to within 0.2 of a degree. The computed slope of the un-iced and iced aircraft longitudinal stability curve is within about 2% of the test data. This work demonstrates the feasibility of a zonal method for the icing analysis of complete aircraft or isolated components within the linear angle of attack range. In fact, this zonal technique has allowed for the viscous analysis of a complete aircraft with ice which is currently not otherwise considered tractable.

A world of entrepreneurs: the establishment of international agribusiness during the Spanish pork and poultry boom, 1950-2000.

PubMed

Clar, Ernesto

2010-01-01

The development of intensive livestock farming in Western Europe after 1950 has been somewhat overlooked by historians, except in a number of macroeconomic works. This process has generally been understood as the application of the American agribusiness model to the European livestock sector through the direct and vertical connection between large feed companies and local farmers. Spain is a good place to test this idea, given the phenomenal expansion experienced by its livestock sector in the second half of the twentieth century and the strong influence large multinational, particularly American, feed manufacturers had on this growth. Oral histories offer insight into the microeconomic forces at work in the recent development of Spanish livestock farming and highlight the role of local entrepreneurs in the establishment of livestock agribusiness.

Electrokinetic acceleration of DNA hybridization in microsystems.

PubMed

Lei, Kin Fong; Wang, Yun-Hsiang; Chen, Huai-Yi; Sun, Jia-Hong; Cheng, Ji-Yen

2015-06-01

In this work, electrokinetic acceleration of DNA hybridization was investigated by different combinations of frequencies and amplitudes of actuating electric signals. Because the frequencies from low to high can induce different kinds of electrokinetic forces, i.e., electroosmotic to electrothermal forces, this work provides an in-depth investigation of electrokinetic enhanced hybridization. Concentric circular Cr/Au microelectrodes of 350 µm in diameter were fabricated on a glass substrate and probe DNA was immobilized on the electrode surface. Target DNA labeled with fluorescent dyes suspending in solution was then applied to the electrode. Different electrokinetic forces were induced by the application of different electric signals to the circular microelectrodes. Local microfluidic vortexes were generated to increase the collision efficiency between the target DNA suspending in solution and probe DNA immobilized on the electrode surface. DNA hybridization on the electrode surface could be accelerated by the electrokinetic forces. The level of hybridization was represented by the fluorescent signal intensity ratio. Results revealed that such 5-min dynamic hybridization increased 4.5 fold of signal intensity ratio as compared to a 1-h static hybridization. Moreover, dynamic hybridization was found to have better differentiation ability between specific and non-specific target DNA. This study provides a strategy to accelerate DNA hybridization in microsystems. Copyright © 2015 Elsevier B.V. All rights reserved.

Women's Work, Gender Roles, and Intimate Partner Violence in Nigeria.

PubMed

Gage, Anastasia J; Thomas, Nicholas J

2017-10-01

The purpose of this study was to determine the contribution of women's labor force participation to the risk of intimate partner violence (IPV) victimization in the past 12 months, using data for 20,635 currently married women aged 15-49 years from the 2013 nationally representative Nigeria Demographic and Health Survey. Multilevel logistic regression models of sexual and physical IPV, with interactions between women's work and social norms regarding traditional gender roles, were developed. Approximately 23% of women aged 15-49 years reported IPV victimization in the past 12 months. Results revealed that non-cash work relative to unemployment was positively associated with both forms of IPV victimization, after controlling for other factors. Women's engagement in cash work was positively correlated with sexual IPV. The positive association between cash work and physical IPV victimization was significantly larger for women who resided in localities with greater male approval of wife beating. In localities where husband-dominated decision making was more common, a spousal education gap that favored husbands was more positively associated with sexual IPV. The findings call for integrated IPV prevention and economic empowerment programs that consider gender norms and gender-role beliefs and are adapted to the locality setting, in order to promote social environments in which women can reap the full benefits of their economic empowerment.

An Analysis of Total Force Integration in RED HORSE Organizations

DTIC Science & Technology

2014-03-27

resources 0 5 0 Good remuneration (5) resources 0 4 0 Federal resources for state mission (4) resources 0 3 0 Recruiting from attractive situation (4...assistance to execute staff guidance (2) Deployment augmentation (21) Enhanced morale (5) Federal resources for state mission (4) Good remuneration (5...Local connections (7) Logical UTC organization (1) Long time working together (2) Low remuneration for ARC CC positions (1) Many echelons of

Exploring the Characteristics of a Current Career Training Program at the United Arab Emirates University: A Study of Current Senior Students and Local Employers

ERIC Educational Resources Information Center

Alhawasin, Mohamed

2010-01-01

Collaborations between universities and businesses continue to be a vital and critical indicator of the transition in learning from school-based learning to work-based learning. Most jobs today require postsecondary education, forcing many high school students to enroll in a higher education institution in order to advance their careers. However,…

Life as a NATO Engineer

DTIC Science & Technology

2010-08-01

NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND...management; leads military in case of specialized survey; supervises more than 25 local civilian employees ; acts as technical expert during contract...Security Assistance Force Head- quarters Camp. I knew I could handle the job of project manager, but wondered about acting as contract manager, technical ex

Adaptive local basis set for Kohn–Sham density functional theory in a discontinuous Galerkin framework II: Force, vibration, and molecular dynamics calculations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Gaigong; Lin, Lin, E-mail: linlin@math.berkeley.edu; Computational Research Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720

Recently, we have proposed the adaptive local basis set for electronic structure calculations based on Kohn–Sham density functional theory in a pseudopotential framework. The adaptive local basis set is efficient and systematically improvable for total energy calculations. In this paper, we present the calculation of atomic forces, which can be used for a range of applications such as geometry optimization and molecular dynamics simulation. We demonstrate that, under mild assumptions, the computation of atomic forces can scale nearly linearly with the number of atoms in the system using the adaptive local basis set. We quantify the accuracy of the Hellmann–Feynmanmore » forces for a range of physical systems, benchmarked against converged planewave calculations, and find that the adaptive local basis set is efficient for both force and energy calculations, requiring at most a few tens of basis functions per atom to attain accuracies required in practice. Since the adaptive local basis set has implicit dependence on atomic positions, Pulay forces are in general nonzero. However, we find that the Pulay force is numerically small and systematically decreasing with increasing basis completeness, so that the Hellmann–Feynman force is sufficient for basis sizes of a few tens of basis functions per atom. We verify the accuracy of the computed forces in static calculations of quasi-1D and 3D disordered Si systems, vibration calculation of a quasi-1D Si system, and molecular dynamics calculations of H{sub 2} and liquid Al–Si alloy systems, where we show systematic convergence to benchmark planewave results and results from the literature.« less

Adaptive local basis set for Kohn–Sham density functional theory in a discontinuous Galerkin framework II: Force, vibration, and molecular dynamics calculations

DOE PAGES

Zhang, Gaigong; Lin, Lin; Hu, Wei; ...

2017-01-27

Recently, we have proposed the adaptive local basis set for electronic structure calculations based on Kohn–Sham density functional theory in a pseudopotential framework. The adaptive local basis set is efficient and systematically improvable for total energy calculations. In this paper, we present the calculation of atomic forces, which can be used for a range of applications such as geometry optimization and molecular dynamics simulation. We demonstrate that, under mild assumptions, the computation of atomic forces can scale nearly linearly with the number of atoms in the system using the adaptive local basis set. We quantify the accuracy of the Hellmann–Feynmanmore » forces for a range of physical systems, benchmarked against converged planewave calculations, and find that the adaptive local basis set is efficient for both force and energy calculations, requiring at most a few tens of basis functions per atom to attain accuracies required in practice. Sin ce the adaptive local basis set has implicit dependence on atomic positions, Pulay forces are in general nonzero. However, we find that the Pulay force is numerically small and systematically decreasing with increasing basis completeness, so that the Hellmann–Feynman force is sufficient for basis sizes of a few tens of basis functions per atom. We verify the accuracy of the computed forces in static calculations of quasi-1D and 3D disordered Si systems, vibration calculation of a quasi-1D Si system, and molecular dynamics calculations of H 2 and liquid Al–Si alloy systems, where we show systematic convergence to benchmark planewave results and results from the literature.« less

Adaptive local basis set for Kohn–Sham density functional theory in a discontinuous Galerkin framework II: Force, vibration, and molecular dynamics calculations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Gaigong; Lin, Lin; Hu, Wei

Recently, we have proposed the adaptive local basis set for electronic structure calculations based on Kohn–Sham density functional theory in a pseudopotential framework. The adaptive local basis set is efficient and systematically improvable for total energy calculations. In this paper, we present the calculation of atomic forces, which can be used for a range of applications such as geometry optimization and molecular dynamics simulation. We demonstrate that, under mild assumptions, the computation of atomic forces can scale nearly linearly with the number of atoms in the system using the adaptive local basis set. We quantify the accuracy of the Hellmann–Feynmanmore » forces for a range of physical systems, benchmarked against converged planewave calculations, and find that the adaptive local basis set is efficient for both force and energy calculations, requiring at most a few tens of basis functions per atom to attain accuracies required in practice. Sin ce the adaptive local basis set has implicit dependence on atomic positions, Pulay forces are in general nonzero. However, we find that the Pulay force is numerically small and systematically decreasing with increasing basis completeness, so that the Hellmann–Feynman force is sufficient for basis sizes of a few tens of basis functions per atom. We verify the accuracy of the computed forces in static calculations of quasi-1D and 3D disordered Si systems, vibration calculation of a quasi-1D Si system, and molecular dynamics calculations of H 2 and liquid Al–Si alloy systems, where we show systematic convergence to benchmark planewave results and results from the literature.« less

Adaptive local basis set for Kohn-Sham density functional theory in a discontinuous Galerkin framework II: Force, vibration, and molecular dynamics calculations

NASA Astrophysics Data System (ADS)

Zhang, Gaigong; Lin, Lin; Hu, Wei; Yang, Chao; Pask, John E.

2017-04-01

Recently, we have proposed the adaptive local basis set for electronic structure calculations based on Kohn-Sham density functional theory in a pseudopotential framework. The adaptive local basis set is efficient and systematically improvable for total energy calculations. In this paper, we present the calculation of atomic forces, which can be used for a range of applications such as geometry optimization and molecular dynamics simulation. We demonstrate that, under mild assumptions, the computation of atomic forces can scale nearly linearly with the number of atoms in the system using the adaptive local basis set. We quantify the accuracy of the Hellmann-Feynman forces for a range of physical systems, benchmarked against converged planewave calculations, and find that the adaptive local basis set is efficient for both force and energy calculations, requiring at most a few tens of basis functions per atom to attain accuracies required in practice. Since the adaptive local basis set has implicit dependence on atomic positions, Pulay forces are in general nonzero. However, we find that the Pulay force is numerically small and systematically decreasing with increasing basis completeness, so that the Hellmann-Feynman force is sufficient for basis sizes of a few tens of basis functions per atom. We verify the accuracy of the computed forces in static calculations of quasi-1D and 3D disordered Si systems, vibration calculation of a quasi-1D Si system, and molecular dynamics calculations of H2 and liquid Al-Si alloy systems, where we show systematic convergence to benchmark planewave results and results from the literature.

When high pressure, system constraints, and a social justice mission collide: A socio-structural analysis of emergency department social work services.

PubMed

Moore, Megan; Cristofalo, Margaret; Dotolo, Danae; Torres, Nicole; Lahdya, Alexandra; Ho, Leyna; Vogel, Mia; Forrester, Mollie; Conley, Bonnie; Fouts, Susan

2017-04-01

The emergency department (ED) can be a critical intervention point for many patients with multifaceted needs. Social workers have long been part of interdisciplinary ED teams. This study aimed to contribute to the limited understanding of social worker-patient interactions and factors influencing social work services in this setting. This paper reports a qualitative content analysis of social work medical record notes (N = 1509) of services provided to trauma patients in an urban, public, level 1 trauma center and an in-depth analysis of semi-structured interviews with ED social workers (N = 10). Eight major social work roles were identified: investigator, gatekeeper, resource broker, care coordinator, problem solver, crisis manager, advocate, discharge planner. Analyses revealed a complex interplay between ED social work services and multi-layered contexts. Using a social-ecological framework, we identified the interactions between micro or individual level factors, mezzo or local system level factors and macro environmental and systemic factors that play a role in ED interactions and patient services. Macro-level contextual influences were socio-structural forces including socioeconomic barriers to health, social hierarchies that reflected power differentials between providers and patients, and distrust or bias. Mezzo-level forces were limited resources, lack of healthcare system coordination, a challenging hierarchy within the medical model and the pressure to discharge patients quickly. Micro-level factors included characteristics of patients and social workers, complexity of patient stressors, empathic strain, lack of closure and compassion. All of these forces were at play in patient-social worker interactions and impacted service provision. Social workers were at times able to successfully navigate these forces, yet at other times these challenges were insurmountable. A conceptual model of ED social work and the influences on the patient-social worker interactions was developed to assist in guiding innovative research and practice models to improve services and outcomes in the complex, fast-paced ED. Copyright © 2017 Elsevier Ltd. All rights reserved.

When high pressure, system constraints, and a social justice mission collide: a socio-structural analysis of emergency department social work services

PubMed Central

Cristofalo, Margaret; Dotolo, Danae; Torres, Nicole; Lahdya, Alexandra; Ho, Leyna; Vogel, Mia; Forrester, Mollie; Conley, Bonnie; Fouts, Susan

2017-01-01

The emergency department (ED) can be a critical intervention point for many patients with multifaceted needs. Social workers have long been part of interdisciplinary ED teams. This study aimed to contribute to the limited understanding of social worker-patient interactions and factors influencing social work services in this setting. This paper reports a qualitative content analysis of social work medical record notes (N=1,509) of services provided to trauma patients in an urban, public, level 1 trauma center and an in-depth analysis of semi-structured interviews with ED social workers (N=10). Eight major social work roles were identified: investigator, gatekeeper, resource broker, care coordinator, problem solver, crisis manager, advocate, discharge planner. Analyses revealed a complex interplay between ED social work services and multi-layered contexts. Using a social-ecological framework, we identified the interactions between micro or individual level factors, mezzo or local system level factors and macro environmental and systemic factors that play a role in ED interactions and patient services. Macro-level contextual influences were socio-structural forces including socioeconomic barriers to health, social hierarchies that reflected power differentials between providers and patients, and distrust or bias. Mezzo-level forces were limited resources, lack of healthcare system coordination, a challenging hierarchy within the medical model and the pressure to discharge patients quickly. Micro-level factors included characteristics of patients and social workers, complexity of patient stressors, empathic strain, lack of closure and compassion. All of these forces were at play in patient-social worker interactions and impacted service provision. Social workers were at times able to successfully navigate these forces, yet at other times these challenges were insurmountable. A conceptual model of ED social work and the influences on the patient-social worker interactions was developed to assist in guiding innovative research and practice models to improve services and outcomes in the complex, fast-paced ED. PMID:28214722

Weather Research and Forecasting Model Wind Sensitivity Study at Edwards Air Force Base, CA

NASA Technical Reports Server (NTRS)

Watson, Leela R.; Bauman, William H., III; Hoeth, Brian

2009-01-01

This abstract describes work that will be done by the Applied Meteorology Unit (AMU) in assessing the success of different model configurations in predicting "wind cycling" cases at Edwards Air Force Base, CA (EAFB), in which the wind speeds and directions oscillate among towers near the EAFB runway. The Weather Research and Forecasting (WRF) model allows users to choose among two dynamical cores - the Advanced Research WRF (ARW) and the Non-hydrostatic Mesoscale Model (NMM). There are also data assimilation analysis packages available for the initialization of the WRF model - the Local Analysis and Prediction System (LAPS) and the Advanced Regional Prediction System (ARPS) Data Analysis System (ADAS). Having a series of initialization options and WRF cores, as well as many options within each core, creates challenges for local forecasters, such as determining which configuration options are best to address specific forecast concerns. The goal of this project is to assess the different configurations available and determine which configuration will best predict surface wind speed and direction at EAFB.

The Cytoskeleton and Force Response Mechanisms

NASA Technical Reports Server (NTRS)

Allen, Philip Goodwin

2003-01-01

The long term aim of this project was to define the mechanisms by which cells sense and respond to the physical forces experienced at 1g and missing in microgravity. Identification and characterization of the elements of the cells force response mechanism could provide pathways and molecules to serve as targets for pharmacological intervention to mitigate the pathologic effects of microgravity. Mechanical forces experienced by the organism can be transmitted to cells through molecules that allow cells to bind to the extracellular matrix and through other types of molecules which bind cells to each other. These molecules are coupled in large complexes of proteins to structural elements such as the actin cytoskeleton that give the cell the ability to sense, resist and respond to force. Application of small forces to tissue culture cells causes local elevation of intracellular calcium through stretch activated ion channels, increased tyrosine phosphorylation and a restructuring of the actin cytoskeleton. Using collagen coated iron oxide beads and strong magnets, we can apply different levels of force to cells in culture. We have found that force application causes the cells to polymerize actin at the site of mechanical deformation and unexpectedly, to depolymerize actin across the rest of the cell. Observations of GFP- actin expressing cells demonstrate that actin accumulates at the site of deformation within the first five minutes of force application and is maintained for many tens of minutes after force is removed. Consistent with the reinforcement of the cytoskeletal structures underlying the integrin-bead interaction, force also alters the motion of bound magnetic beads. This effect is seen following the removal of the magnetic field, and is only partially ablated by actin disruption with cytochalsin B. While actin is polymerizing locally at the site of force application, force also stimulates a global reduction in actin filament content within the cells. We have examined the roles of several actin filament disassembly factors in the global reduction of cellular actin filaments. The calcium regulated actin filament severing protein gelsolin is not necessary for the increased actin turnover, as cells derived from gelsolin null and wildtype mice still show a reduction in total actin filament content. Instead, our work suggests that the actin binding protein cofilin may be important for these changes in actin dynamics. Cofilin binds to and enhances the disassembly of actin filaments. Using immunological methods, we observe transient changes in the phosphorylation state of cofilin upon force application that suggests that cofilin may mediate actin filament turnover. Early after force application, cofilin is transiently dephosphorylated, activating its actin disassembly activity. Subsequently, we find a hyper-phosphorylation of cofilin, rendering it inactive. This reduction in cofilin activity may explain the stability of the force induced actin structuttes. In testing this hypothesis, we aimed to generate cells that express the constituitively active kinase (LIM-kinase) that phosphorylates cofilin. lnidial attempts in the cell lines used for the our previous studies proved unsuccessful. While we prepare this work for pubication, we are continuing to study other cell lines and tissue sources to determine whether they show a reduction in F-actin content after force application.

Force generation within tissues during development

NASA Astrophysics Data System (ADS)

Kasza, Karen

During embryonic development, multicellular tissues physically change shape, move, and grow. Changes in epithelial tissue organization are often accomplished by local movements of cells that are driven largely by forces generated by the motor protein myosin II. These forces are patterned to orient cell movements, resulting in changes in tissue shape and organization to build functional tissues and organs. To investigate the mechanisms of force generation in vivo, we use the fruit fly embryo as a model system. Spatial patterns of forces orient cell movements to drive rapid tissue elongation along the head-to-tail axis of the embryo. I will describe how studying embryos generated with engineered myosin variants provides insight into where, when, and how forces are generated to efficiently reorganize tissues. We found that a myosin variant that is locked-in to the active or ``on'' state accelerates cell movements, while two mutant myosin variants associated with human disease produce slowed cell movement. These myosin variants all disrupt tissue elongation, but live imaging and biophysical measurements reveal distinct effects on myosin organization and dynamics within cells and uncover mechanisms that control the spatial and temporal patterns of force generation. These studies shed light not only on how defects in force generation contribute to disease but also on physical principles at work in active, living materials.

Local knowledge, environmental politics, and the founding of ecology in the United States. Stephen Forbes and "The Lake as a Microcosm" (1887).

PubMed

Schneider, D W

2000-12-01

Stephen Forbes's "The Lake as a Microcosm" is one of the founding documents of the science of ecology in the United States. By tracing the connections between scientists and local fishermen underlying the research on floodplain lakes presented in "The Lake as a Microcosm," this essay shows how the birth of ecology was tied to local knowledge and the local politics of environmental transformation. Forbes and the other scientists of the Illinois Natural History Survey relied on fishermen for manual labor, expertise in catching fish, and knowledge of the natural history of the fishes. As Forbes and his colleagues worked in close contact with fishermen, they also adopted many of their political concerns over the privatization of the floodplain and became politically active in supporting their interests. The close connection between scientists and local knowledge forced the ecologists to reframe the boundaries of ecology as objective or political, pure or applied, local or scientific.

Dynamics of particulate organic matter composition in coastal systems: Forcing of spatio-temporal variability at multi-systems scale

NASA Astrophysics Data System (ADS)

Liénart, Camilla; Savoye, Nicolas; David, Valérie; Ramond, Pierre; Rodriguez Tress, Paco; Hanquiez, Vincent; Marieu, Vincent; Aubert, Fabien; Aubin, Sébastien; Bichon, Sabrina; Boinet, Christophe; Bourasseau, Line; Bozec, Yann; Bréret, Martine; Breton, Elsa; Caparros, Jocelyne; Cariou, Thierry; Claquin, Pascal; Conan, Pascal; Corre, Anne-Marie; Costes, Laurence; Crouvoisier, Muriel; Del Amo, Yolanda; Derriennic, Hervé; Dindinaud, François; Duran, Robert; Durozier, Maïa; Devesa, Jérémy; Ferreira, Sophie; Feunteun, Eric; Garcia, Nicole; Geslin, Sandrine; Grossteffan, Emilie; Gueux, Aurore; Guillaudeau, Julien; Guillou, Gaël; Jolly, Orianne; Lachaussée, Nicolas; Lafont, Michel; Lagadec, Véronique; Lamoureux, Jézabel; Lauga, Béatrice; Lebreton, Benoît; Lecuyer, Eric; Lehodey, Jean-Paul; Leroux, Cédric; L'Helguen, Stéphane; Macé, Eric; Maria, Eric; Mousseau, Laure; Nowaczyk, Antoine; Pineau, Philippe; Petit, Franck; Pujo-Pay, Mireille; Raimbault, Patrick; Rimmelin-Maury, Peggy; Rouaud, Vanessa; Sauriau, Pierre-Guy; Sultan, Emmanuelle; Susperregui, Nicolas

2018-03-01

In costal systems, particulate organic matter (POM) results from a multiplicity of sources having their respective dynamics in terms of production, decomposition, transport and burial. The POM pool experiences thus considerable spatial and temporal variability. In order to better understand this variability, the present study employs statistical multivariate analyses to investigate links between POM composition and environmental forcings for a panel of twelve coastal systems distributed along the three maritime regions of France and monitored weekly to monthly for 1 to 8 years. At multi-system scale, two main gradients of POC composition have been identified: a 'Continent-Ocean' gradient associated with hydrodynamics, sedimentary dynamics and depth of the water column, and a gradient of trophic status related to nutrient availability. At local scale, seasonality of POC composition appears to be station-specific but still related to part of the above-mentioned forcings. A typology of systems was established by coupling spatial and temporal variability of POC composition. Four groups were highlighted: (1) the estuarine stations where POC composition is dominated by terrestrial POM and driven by hydrodynamics and sedimentary processes, (2) the oligotrophic systems, characterized by the contribution of diazotrophs due to low nutrient availability, and the marine meso/eutroph systems whose POC composition is (3) either deeply dominated by phytoplankton or (4) dominated by phytoplankton but where the contribution of continental and benthic POC is not negligible and is driven by hydrodynamics, sedimentary processes and the height of the water column. Finally, the present study provides several insights into the different forcings to POM composition and dynamics in temperate coastal systems at local and multi-system scales. This work also presents a methodological approach that establishes statistical links between forcings and POM composition, helping to gain more objectively insight of forcings.

Nonlinear critical-layer evolution of a forced gravity wave packet

NASA Astrophysics Data System (ADS)

Campbell, L. J.; Maslowe, S. A.

2003-10-01

In this paper, numerical simulations are presented of the nonlinear critical-layer evolution of a forced gravity wave packet in a stratified shear flow. The wave packet, localized in the horizontal direction, is forced at the lower boundary of a two-dimensional domain and propagates vertically towards the critical layer. The wave mean-flow interactions in the critical layer are investigated numerically and contrasted with the results obtained using a spatially periodic monochromatic forcing. With the horizontally localized forcing, the net absorption of the disturbance at the critical layer continues for large time and the onset of the nonlinear breakdown is delayed compared with the case of monochromatic forcing. There is an outward flux of momentum in the horizontal direction so that the horizontal extent of the packet increases with time. The extent to which this happens depends on a number of factors including the amplitude and horizontal length of the forcing. It is also seen that the prolonged absorption of the disturbance stabilizes the solution to the extent that it is always convectively stable; the local Richardson number remains positive well into the nonlinear regime. In this respect, our results for the localized forcing differ from those in the case of monochromatic forcing where significant regions with negative Richardson number appear.

YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis

PubMed Central

Lin, Chuwen; Yao, Erica; Zhang, Kuan; Jiang, Xuan; Croll, Stacey; Thompson-Peer, Katherine; Chuang, Pao-Tien

2017-01-01

Branching morphogenesis is a fundamental program for tissue patterning. We show that active YAP, a key mediator of Hippo signaling, is distributed throughout the murine lung epithelium and loss of epithelial YAP severely disrupts branching. Failure to branch is restricted to regions where YAP activity is removed. This suggests that YAP controls local epithelial cell properties. In support of this model, mechanical force production is compromised and cell proliferation is reduced in Yap mutant lungs. We propose that defective force generation and insufficient epithelial cell number underlie the branching defects. Through genomic analysis, we also uncovered a feedback control of pMLC levels, which is critical for mechanical force production, likely through the direct induction of multiple regulators by YAP. Our work provides a molecular pathway that could control epithelial cell properties required for proper morphogenetic movement and pattern formation. DOI: http://dx.doi.org/10.7554/eLife.21130.001 PMID:28323616

Observer efficiency in free-localization tasks with correlated noise.

PubMed

Abbey, Craig K; Eckstein, Miguel P

2014-01-01

The efficiency of visual tasks involving localization has traditionally been evaluated using forced choice experiments that capitalize on independence across locations to simplify the performance of the ideal observer. However, developments in ideal observer analysis have shown how an ideal observer can be defined for free-localization tasks, where a target can appear anywhere in a defined search region and subjects respond by localizing the target. Since these tasks are representative of many real-world search tasks, it is of interest to evaluate the efficiency of observer performance in them. The central question of this work is whether humans are able to effectively use the information in a free-localization task relative to a similar task where target location is fixed. We use a yes-no detection task at a cued location as the reference for this comparison. Each of the tasks is evaluated using a Gaussian target profile embedded in four different Gaussian noise backgrounds having power-law noise power spectra with exponents ranging from 0 to 3. The free localization task had a square 6.7° search region. We report on two follow-up studies investigating efficiency in a detect-and-localize task, and the effect of processing the white-noise backgrounds. In the fixed-location detection task, we find average observer efficiency ranges from 35 to 59% for the different noise backgrounds. Observer efficiency improves dramatically in the tasks involving localization, ranging from 63 to 82% in the forced localization tasks and from 78 to 92% in the detect-and- localize tasks. Performance in white noise, the lowest efficiency condition, was improved by filtering to give them a power-law exponent of 2. Classification images, used to examine spatial frequency weights for the tasks, show better tuning to ideal weights in the free-localization tasks. The high absolute levels of efficiency suggest that observers are well-adapted to free-localization tasks.

Observer efficiency in free-localization tasks with correlated noise

PubMed Central

Abbey, Craig K.; Eckstein, Miguel P.

2014-01-01

The efficiency of visual tasks involving localization has traditionally been evaluated using forced choice experiments that capitalize on independence across locations to simplify the performance of the ideal observer. However, developments in ideal observer analysis have shown how an ideal observer can be defined for free-localization tasks, where a target can appear anywhere in a defined search region and subjects respond by localizing the target. Since these tasks are representative of many real-world search tasks, it is of interest to evaluate the efficiency of observer performance in them. The central question of this work is whether humans are able to effectively use the information in a free-localization task relative to a similar task where target location is fixed. We use a yes-no detection task at a cued location as the reference for this comparison. Each of the tasks is evaluated using a Gaussian target profile embedded in four different Gaussian noise backgrounds having power-law noise power spectra with exponents ranging from 0 to 3. The free localization task had a square 6.7° search region. We report on two follow-up studies investigating efficiency in a detect-and-localize task, and the effect of processing the white-noise backgrounds. In the fixed-location detection task, we find average observer efficiency ranges from 35 to 59% for the different noise backgrounds. Observer efficiency improves dramatically in the tasks involving localization, ranging from 63 to 82% in the forced localization tasks and from 78 to 92% in the detect-and- localize tasks. Performance in white noise, the lowest efficiency condition, was improved by filtering to give them a power-law exponent of 2. Classification images, used to examine spatial frequency weights for the tasks, show better tuning to ideal weights in the free-localization tasks. The high absolute levels of efficiency suggest that observers are well-adapted to free-localization tasks. PMID:24817854

p{sup +}-doping analysis of laser fired contacts for silicon solar cells by Kelvin probe force microscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ebser, J., E-mail: Jan.Ebser@uni-konstanz.de; Sommer, D.; Fritz, S.

Local rear contacts for silicon passivated emitter and rear contact solar cells can be established by point-wise treating an Al layer with laser radiation and thereby establishing an electrical contact between Al and Si bulk through the dielectric passivation layer. In this laser fired contacts (LFC) process, Al can establish a few μm thick p{sup +}-doped Si region below the metal/Si interface and forms in this way a local back surface field which reduces carrier recombination at the contacts. In this work, the applicability of Kelvin probe force microscopy (KPFM) to the investigation of LFCs considering the p{sup +}-doping distributionmore » is demonstrated. The method is based on atomic force microscopy and enables the evaluation of the lateral 2D Fermi-level characteristics at sub-micrometer resolution. The distribution of the electrical potential and therefore the local hole concentration in and around the laser fired region can be measured. KPFM is performed on mechanically polished cross-sections of p{sup +}-doped Si regions formed by the LFC process. The sample preparation is of great importance because the KPFM signal is very surface sensitive. Furthermore, the measurement is responsive to sample illumination and the height of the applied voltage between tip and sample. With other measurement techniques like micro-Raman spectroscopy, electrochemical capacitance-voltage, and energy dispersive X-ray analysis, a high local hole concentration in the range of 10{sup 19 }cm{sup −3} is demonstrated in the laser fired region. This provides, in combination with the high spatial resolution of the doping distribution measured by KPFM, a promising approach for microscopic understanding and further optimization of the LFC process.« less

The electromigration force in metallic bulk

NASA Astrophysics Data System (ADS)

Lodder, A.; Dekker, J. P.

1998-01-01

The voltage induced driving force on a migrating atom in a metallic system is discussed in the perspective of the Hellmann-Feynman force concept, local screening concepts and the linear-response approach. Since the force operator is well defined in quantum mechanics it appears to be only confusing to refer to the Hellmann-Feynman theorem in the context of electromigration. Local screening concepts are shown to be mainly of historical value. The physics involved is completely represented in ab initio local density treatments of dilute alloys and the implementation does not require additional precautions about screening, being typical for jellium treatments. The linear-response approach is shown to be a reliable guide in deciding about the two contributions to the driving force, the direct force and the wind force. Results are given for the wind valence for electromigration in a number of FCC and BCC metals, calculated using an ab initio KKR-Green's function description of a dilute alloy.

Stochastic Ratcheting on a Funneled Energy Landscape Is Necessary for Highly Efficient Contractility of Actomyosin Force Dipoles

NASA Astrophysics Data System (ADS)

Komianos, James E.; Papoian, Garegin A.

2018-04-01

Current understanding of how contractility emerges in disordered actomyosin networks of nonmuscle cells is still largely based on the intuition derived from earlier works on muscle contractility. In addition, in disordered networks, passive cross-linkers have been hypothesized to percolate force chains in the network, hence, establishing large-scale connectivity between local contractile clusters. This view, however, largely overlooks the free energy of cross-linker binding at the microscale, which, even in the absence of active fluctuations, provides a thermodynamic drive towards highly overlapping filamentous states. In this work, we use stochastic simulations and mean-field theory to shed light on the dynamics of a single actomyosin force dipole—a pair of antiparallel actin filaments interacting with active myosin II motors and passive cross-linkers. We first show that while passive cross-linking without motor activity can produce significant contraction between a pair of actin filaments, driven by thermodynamic favorability of cross-linker binding, a sharp onset of kinetic arrest exists at large cross-link binding energies, greatly diminishing the effectiveness of this contractility mechanism. Then, when considering an active force dipole containing nonmuscle myosin II, we find that cross-linkers can also serve as a structural ratchet when the motor dissociates stochastically from the actin filaments, resulting in significant force amplification when both molecules are present. Our results provide predictions of how actomyosin force dipoles behave at the molecular level with respect to filament boundary conditions, passive cross-linking, and motor activity, which can explicitly be tested using an optical trapping experiment.

Issues and Concerns for Local Government: Virginia in the 1990s.

ERIC Educational Resources Information Center

Crockett, Mark

Many challenges face local governments in Virginia and nationwide in the 1990s. As federal funding has decreased, local governments have been forced to take on greater responsibilities. This increased workload has created a greater demand for resources and forced many localities to raise taxes. Citizens have often voiced opposition to these tax…

How Force Might Activate Talin's Vinculin Binding Sites: SMD Reveals a Structural Mechanism

PubMed Central

Hytönen, Vesa P; Vogel, Viola

2008-01-01

Upon cell adhesion, talin physically couples the cytoskeleton via integrins to the extracellular matrix, and subsequent vinculin recruitment is enhanced by locally applied tensile force. Since the vinculin binding (VB) sites are buried in the talin rod under equilibrium conditions, the structural mechanism of how vinculin binding to talin is force-activated remains unknown. Taken together with experimental data, a biphasic vinculin binding model, as derived from steered molecular dynamics, provides high resolution structural insights how tensile mechanical force applied to the talin rod fragment (residues 486–889 constituting helices H1–H12) might activate the VB sites. Fragmentation of the rod into three helix subbundles is prerequisite to the sequential exposure of VB helices to water. Finally, unfolding of a VB helix into a completely stretched polypeptide might inhibit further binding of vinculin. The first events in fracturing the H1–H12 rods of talin1 and talin2 in subbundles are similar. The proposed force-activated α-helix swapping mechanism by which vinculin binding sites in talin rods are exposed works distinctly different from that of other force-activated bonds, including catch bonds. PMID:18282082

Auxiliary field diffusion Monte Carlo calculations of light and medium-mass nuclei with local chiral interactions

NASA Astrophysics Data System (ADS)

Lonardoni, D.; Gandolfi, S.; Lynn, J. E.; Petrie, C.; Carlson, J.; Schmidt, K. E.; Schwenk, A.

2018-04-01

Quantum Monte Carlo methods have recently been employed to study properties of nuclei and infinite matter using local chiral effective-field-theory interactions. In this work, we present a detailed description of the auxiliary field diffusion Monte Carlo algorithm for nuclei in combination with local chiral two- and three-nucleon interactions up to next-to-next-to-leading order. We show results for the binding energy, charge radius, charge form factor, and Coulomb sum rule in nuclei with 3 ≤A ≤16 . Particular attention is devoted to the effect of different operator structures in the three-body force for different cutoffs. The outcomes suggest that local chiral interactions fit to few-body observables give a very good description of the ground-state properties of nuclei up to 16O, with the exception of one fit for the softer cutoff which predicts overbinding in larger nuclei.

Paths to Victory: Detailed Insurgency Case Studies

DTIC Science & Technology

2013-01-01

insurgency with informers , spies, and double agents. Eager to snuff out insurgent cross-border sanctuaries, Spinola exe- cuted Operation Mal Verde, a ...fruit when Magaia was shot dead by a fellow FRELIMO fighter suspected of being a double agent working for the COIN force, a move that exploited the...established a network of informants in the local community and, to some degree, within the Clandestine Front as well. It also relied heavily on

Environmental Assessment for Construction of Storm Water Detection System at Storm Water Outfall #3, Malmstrom Air Force Base, Montana

DTIC Science & Technology

2007-08-01

germination success for grass (i.e. hydro-mulch seeding ); 6. To prevent overloading of the aforementioned water containment methods, this work shall...12. DISTRIBUTION/ AVAILABILITY STATEMENT Approved for public release; distribution unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT The United...was made available for a 30-day federal, state, and local agency and public review and comment period through publication of a notice of

Corps Work Force Mobility.

DTIC Science & Technology

1979-08-01

particular attention. Expressed Mobility (as stated on career program forms) was compared to actual mobility and revealed a close correla- tion. The...i 1 Introduction 1 2 How Mobile Are Corps Employees ? 2 3 Why Do Corps Employees Move? 5 4 When Do Corps Employees Move? 7 5 What Influence Does Locale...Have On Mobility? 11 6 Real Versus Stated Mobility 16 7 Conclusion 21 Figure 1 Career Mobility 3 2 Motivation for Employee Mobility 6 3 Frequency of

Gex-Model Using Local Area Fraction for Binary Electrolyte Systems

NASA Astrophysics Data System (ADS)

Haghtalab, Ali; Joda, Marzieh

2007-06-01

The correlation and prediction of phase equilibria of electrolyte systems are essential in the design and operation of many industrial processes such as downstream processing in biotechnology, desalination, hydrometallurgy, etc. In this research, the local composition non-random two liquid-nonrandom factor (NRTL-NRF) model of Haghtalab and Vera was extended for uni-univalent aqueous electrolyte solutions. Based on the assumptions of the NRTL-NRF model, excess Gibbs free energy ( g E) functions were derived for binary electrolyte systems. In this work, the local area fraction was applied and the modified model of NRTL-NRF was developed with either an equal or unequal surface area of an anion to the surface area of a cation. The modified NRTL-NRF models consist of two contributions, one due to long-range forces represented by the Debye-Hückel theory, and the other due to short-range forces, represented by local area fractions of species through nonrandom factors. Each model contains only two adjustable parameters per electrolyte. In addition, the model with unequal surface area of ionic species gives better results in comparison with the second new model with equal surface area of ions. The results for the mean activity coefficients for aqueous solutions of uni-univalent electrolytes at 298.15 K showed that the present model is more accurate than the original NRTL-NRF model.

Contact angle and local wetting at contact line.

PubMed

Li, Ri; Shan, Yanguang

2012-11-06

This theoretical study was motivated by recent experiments and theoretical work that had suggested the dependence of the static contact angle on the local wetting at the triple-phase contact line. We revisit this topic because the static contact angle as a local wetting parameter is still not widely understood and clearly known. To further clarify the relationship of the static contact angle with wetting, two approaches are applied to derive a general equation for the static contact angle of a droplet on a composite surface composed of heterogeneous components. A global approach based on the free surface energy of a thermodynamic system containing the droplet and solid surface shows the static contact angle as a function of local surface chemistry and local wetting state at the contact line. A local approach, in which only local forces acting on the contact line are considered, results in the same equation. The fact that the local approach agrees with the global approach further demonstrates the static contact angle as a local wetting parameter. Additionally, the study also suggests that the wetting described by the Wenzel and Cassie equations is also the local wetting of the contact line rather than the global wetting of the droplet.

Numerical Study of Rotating Turbulence with External Forcing

NASA Technical Reports Server (NTRS)

Yeung, P. K.; Zhou, Ye

1998-01-01

Direct numerical simulation at 256(exp 3) resolution have been carried out to study the response of isotropic turbulence to the concurrent effects of solid-body rotation and numerical forcing at the large scales. Because energy transfer to the smaller scales is weakened by rotation, energy input from forcing gradually builds up at the large scales, causing the overall kinetic energy to increase. At intermediate wavenumbers the energy spectrum undergoes a transition from a limited k(exp -5/3) inertial range to k(exp -2) scaling recently predicted in the literature. Although the Reynolds stress tensor remains approximately isotropic and three-components, evidence for anisotropy and quasi- two-dimensionality in length scales and spectra in different velocity components and directions is strong. The small scales are found to deviate from local isotropy, primarily as a result of anisotropic transfer to the high wavenumbers. To understand the spectral dynamics of this flow we study the detailed behavior of nonlinear triadic interactions in wavenumber space. Spectral transfer in the velocity component parallel to the axis of rotation is qualitatively similar to that in non-rotating turbulence; however the perpendicular component is characterized by a greatly suppressed energy cascade at high wavenumber and a local reverse transfer at the largest scales. The broader implications of this work are briefly addressed.

A Systematic Exploration of the Local and Remote Climate Effects of Anthropogenic Aerosol Emissions from Key Regions

NASA Astrophysics Data System (ADS)

Voulgarakis, A.; Kasoar, M.; Shawki, D.; Lamarque, J. F.; Shindell, D. T.; Faluvegi, G.; Bellouin, N.; Collins, W.; Tsigaridis, K.

2016-12-01

The radiative forcing of short-lived pollutants such as aerosols and tropospheric ozone is highly inhomogeneous and can therefore affect regional temperature, circulation and precipitation in a much more complicated way than the forcing of well-mixed greenhouse gases. Such effects have only recently started to be examined thoroughly and systematically from a global point of view, to understand regional interactions. Here, after outlining some key past work in this area, results from recent simulations with the UK Met Office's HadGEM3 global composition-climate model will be presented in which anthropogenic emissions of sulfur dioxide (SO2) and black carbon in key regions (East Asia, South Asia, Europe, the US, and the northern mid-latitudes as a whole) have been removed. The linkages between emissions, concentrations, radiative forcing, temperature and precipitation responses will be discussed. A particular emphasis will be placed on non-local effects, i.e. how emissions over a certain region can affect other areas remotely. Finally, we will contrast our results with those from similar experiments pursued using the NASA GISS-E2 and the NCAR CESM1 models for US and East Asian SO2 emissions, and will discuss the large differences in the models' behaviour.

Breakdown of Amontons' Law of Friction in Sheared-Elastomer with Local Amontons' Friction

NASA Astrophysics Data System (ADS)

Matsukawa, Hiroshi; Otsuki, Michio

2012-02-01

It is well known that Amontons' law of friction i.e. the frictional force against the sliding motion of solid object is proportional to the loading force and not dependent on the contact area, holds well for various systems. Here we show, however, the breakdown of the Amontons' law for the elastic object which have local friction obeying Amontons' law and is under uniform pressure by FEM calculation The external shearing force applied to the trailing edge of the sample induces local slip. The range of the slip increases with the increasing external force adiabatically at first. When the range reaches the critical magnitude, the slips moves rapidly and reaches the leading edge of the sample then the whole system slides. These behaviors are consistent with the experiment by Rubinstein et.al. (Phys. Rev. Lett. 98, 226103). The static frictional coefficient, the ratio between the static frictional force for the whole system and the loading force, decreases with the increasing pressure. This means the breakdown of Amontons' law. The pressure dependence of the frictional coefficient is caused by the change of the critical length of the local slip. The behaviors of the local slip and the frictional coefficient are well explained by the 1 dimensional model analytically.

Localization of adhesins on the surface of a pathogenic bacterial envelope through atomic force microscopy

NASA Astrophysics Data System (ADS)

Arnal, L.; Longo, G.; Stupar, P.; Castez, M. F.; Cattelan, N.; Salvarezza, R. C.; Yantorno, O. M.; Kasas, S.; Vela, M. E.

2015-10-01

Bacterial adhesion is the first and a significant step in establishing infection. This adhesion normally occurs in the presence of flow of fluids. Therefore, bacterial adhesins must be able to provide high strength interactions with their target surface in order to maintain the adhered bacteria under hydromechanical stressing conditions. In the case of B. pertussis, a Gram-negative bacterium responsible for pertussis, a highly contagious human respiratory tract infection, an important protein participating in the adhesion process is a 220 kDa adhesin named filamentous haemagglutinin (FHA), an outer membrane and also secreted protein that contains recognition domains to adhere to ciliated respiratory epithelial cells and macrophages. In this work, we obtained information on the cell-surface localization and distribution of the B. pertussis adhesin FHA using an antibody-functionalized AFM tip. Through the analysis of specific molecular recognition events we built a map of the spatial distribution of the adhesin which revealed a non-homogeneous pattern. Moreover, our experiments showed a force induced reorganization of the adhesin on the surface of the cells, which could explain a reinforced adhesive response under external forces. This single-molecule information contributes to the understanding of basic molecular mechanisms used by bacterial pathogens to cause infectious disease and to gain insights into the structural features by which adhesins can act as force sensors under mechanical shear conditions.Bacterial adhesion is the first and a significant step in establishing infection. This adhesion normally occurs in the presence of flow of fluids. Therefore, bacterial adhesins must be able to provide high strength interactions with their target surface in order to maintain the adhered bacteria under hydromechanical stressing conditions. In the case of B. pertussis, a Gram-negative bacterium responsible for pertussis, a highly contagious human respiratory tract infection, an important protein participating in the adhesion process is a 220 kDa adhesin named filamentous haemagglutinin (FHA), an outer membrane and also secreted protein that contains recognition domains to adhere to ciliated respiratory epithelial cells and macrophages. In this work, we obtained information on the cell-surface localization and distribution of the B. pertussis adhesin FHA using an antibody-functionalized AFM tip. Through the analysis of specific molecular recognition events we built a map of the spatial distribution of the adhesin which revealed a non-homogeneous pattern. Moreover, our experiments showed a force induced reorganization of the adhesin on the surface of the cells, which could explain a reinforced adhesive response under external forces. This single-molecule information contributes to the understanding of basic molecular mechanisms used by bacterial pathogens to cause infectious disease and to gain insights into the structural features by which adhesins can act as force sensors under mechanical shear conditions. Electronic supplementary information (ESI) available. See DOI: 10.1039/c5nr04644k

Force distribution in a semiflexible loop.

PubMed

Waters, James T; Kim, Harold D

2016-04-01

Loops undergoing thermal fluctuations are prevalent in nature. Ringlike or cross-linked polymers, cyclic macromolecules, and protein-mediated DNA loops all belong to this category. Stability of these molecules are generally described in terms of free energy, an average quantity, but it may also be impacted by local fluctuating forces acting within these systems. The full distribution of these forces can thus give us insights into mechanochemistry beyond the predictive capability of thermodynamics. In this paper, we study the force exerted by an inextensible semiflexible polymer constrained in a looped state. By using a simulation method termed "phase-space sampling," we generate the equilibrium distribution of chain conformations in both position and momentum space. We compute the constraint forces between the two ends of the loop in this chain ensemble using Lagrangian mechanics, and show that the mean of these forces is equal to the thermodynamic force. By analyzing kinetic and potential contributions to the forces, we find that the mean force acts in the direction of increasing extension not because of bending stress, but in spite of it. Furthermore, we obtain a distribution of constraint forces as a function of chain length, extension, and stiffness. Notably, increasing contour length decreases the average force, but the additional freedom allows fluctuations in the constraint force to increase. The force distribution is asymmetric and falls off less sharply than a Gaussian distribution. Our work exemplifies a system where large-amplitude fluctuations occur in a way unforeseen by a purely thermodynamic framework, and offers computational tools useful for efficient, unbiased simulation of a constrained system.

Force distribution in a semiflexible loop

PubMed Central

Waters, James T.; Kim, Harold D.

2017-01-01

Loops undergoing thermal fluctuations are prevalent in nature. Ringlike or cross-linked polymers, cyclic macromolecules, and protein-mediated DNA loops all belong to this category. Stability of these molecules are generally described in terms of free energy, an average quantity, but it may also be impacted by local fluctuating forces acting within these systems. The full distribution of these forces can thus give us insights into mechanochemistry beyond the predictive capability of thermodynamics. In this paper, we study the force exerted by an inextensible semiflexible polymer constrained in a looped state. By using a simulation method termed “phase-space sampling,” we generate the equilibrium distribution of chain conformations in both position and momentum space. We compute the constraint forces between the two ends of the loop in this chain ensemble using Lagrangian mechanics, and show that the mean of these forces is equal to the thermodynamic force. By analyzing kinetic and potential contributions to the forces, we find that the mean force acts in the direction of increasing extension not because of bending stress, but in spite of it. Furthermore, we obtain a distribution of constraint forces as a function of chain length, extension, and stiffness. Notably, increasing contour length decreases the average force, but the additional freedom allows fluctuations in the constraint force to increase. The force distribution is asymmetric and falls off less sharply than a Gaussian distribution. Our work exemplifies a system where large-amplitude fluctuations occur in a way unforeseen by a purely thermodynamic framework, and offers computational tools useful for efficient, unbiased simulation of a constrained system. PMID:27176436

Static Footprint Local Forces, Areas, and Aspect Ratios for Three Type 7 Aircraft Tires

NASA Technical Reports Server (NTRS)

Howell, William E.; Perez, Sharon E.; Vogler, William A.

1991-01-01

The National Tire Modeling Program (NTMP) is a joint NASA/industry effort to improve the understanding of tire mechanics and develop accurate analytical design tools. This effort includes fundamental analytical and experimental research on the structural mechanics of tires. Footprint local forces, areas, and aspect ratios were measured. Local footprint forces in the vertical, lateral, and drag directions were measured with a special footprint force transducer. Measurements of the local forces in the footprint were obtained by positioning the transducer at specified locations within the footprint and externally loading the tires. Three tires were tested: (1) one representative of those used on the main landing gear of B-737 and DC-9 commercial transport airplanes, (2) a nose landing gear tire for the Space Shuttle Orbiter, and (3) a main landing gear tire for the Space Shuttle Orbiter. Data obtained for various inflation pressures and vertical loads are presented for two aircraft tires. The results are presented in graphical and tabulated forms.

Analysis of capacitive force acting on a cantilever tip at solid/liquid interfaces

NASA Astrophysics Data System (ADS)

Umeda, Ken-ichi; Kobayashi, Kei; Oyabu, Noriaki; Hirata, Yoshiki; Matsushige, Kazumi; Yamada, Hirofumi

2013-04-01

Dielectric properties of biomolecules or biomembranes are directly related to their structures and biological activities. Capacitance force microscopy based on the cantilever deflection detection is a useful scanning probe technique that can map local dielectric constant. Here we report measurements and analysis of the capacitive force acting on a cantilever tip at solid/liquid interfaces induced by application of an alternating voltage to explore the feasibility of the measurements of local dielectric constant by the voltage modulation technique in aqueous solutions. The results presented here suggest that the local dielectric constant measurements by the conventional voltage modulation technique are basically possible even in polar liquid media. However, the cantilever deflection is not only induced by the electrostatic force, but also by the surface stress, which does not include the local dielectric information. Moreover, since the voltage applied between the tip and sample are divided by the electric double layer and the bulk polar liquid, the capacitive force acting on the apex of the tip are strongly attenuated. For these reasons, the lateral resolution in the local dielectric constant measurements is expected to be deteriorated in polar liquid media depending on the magnitude of dielectric response. Finally, we present the criteria for local dielectric constant measurements with a high lateral resolution in polar liquid media.

The response of the East Asia summer precipitation to greenhouse gases and anthropogenic aerosols

NASA Astrophysics Data System (ADS)

Tian, Fangxing; Dong, Buwen; Robson, Jon; Sutton, Rowan

2017-04-01

The changes of precipitation over China since the mid-20th century display a dipole trend pattern over eastern China, which is known as Southern-Flood-Northern-Drought (SFND) pattern. The trends have been attributed to different factors, such as the changes of aerosol and greenhouse gas emissions. However much less is known about the different effects of these factors on generating the SFND pattern. This work investigated the drivers and dynamical mechanisms by using a atmosphere-ocean-mixed-layer model forced by anthropogenic greenhouse gase (GHG), anthropogenic aerosol (AA) and the combined effects. The model experiments with different forcings indicates that the GHG forcing dominates the precipitation increase, which is stronger over south China than over north China. On the other hand, the drought over north China is dominated by the AA forcing. Analysis of physical processes indicates that the GHG forcing increases the moisture and leads to strong convergence over east China, and then more precipitation. The AA forcing leads to north wind anomalies and generates divergent anomalies over north China, which reduces the precipitation. Further analysis indicates that the changes of the circulation which related to the SFND pattern are forced by the enhancement of the Western North Pacific Subtropical High (WNPSH). Both GHG and AA forcing can enhance the WNPSH by changing the local Hadley cell.

The Role of MreB in Escherichia Coli's Cellular Rigidity

NASA Astrophysics Data System (ADS)

Shaevitz, Joshua W.

2009-03-01

Bacteria possess homologs of all three classes of eukaryotic cytoskeletal proteins. These filamentous proteins have been shown to localize proteins essential for a number of cell-biological processes in prokaryotes such as cell growth and division. However, to date, there has been no direct evidence that the cytoskeleton in bacteria bears mechanical loads or can generate physical forces than are used by the cell. I will present evidence from combined fluorescence and force microscopy measurements that MreB, an actin homolog, is responsible for half of Escherichia coli's cellular rigidity. These data support an interpretation in which the cytoskeleton, the peptidoglycan cell wall and a large turgor pressure work together to give gram-negative cells their mechanical properties.

A proposed experimental search for chameleons using asymmetric parallel plates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burrage, Clare; Copeland, Edmund J.; Stevenson, James A., E-mail: Clare.Burrage@nottingham.ac.uk, E-mail: ed.copeland@nottingham.ac.uk, E-mail: james.stevenson@nottingham.ac.uk

2016-08-01

Light scalar fields coupled to matter are a common consequence of theories of dark energy and attempts to solve the cosmological constant problem. The chameleon screening mechanism is commonly invoked in order to suppress the fifth forces mediated by these scalars, sufficiently to avoid current experimental constraints, without fine tuning. The force is suppressed dynamically by allowing the mass of the scalar to vary with the local density. Recently it has been shown that near future cold atoms experiments using atom-interferometry have the ability to access a large proportion of the chameleon parameter space. In this work we demonstrate howmore » experiments utilising asymmetric parallel plates can push deeper into the remaining parameter space available to the chameleon.« less

Surface and local electronic structure modification of MgO film using Zn and Fe ion implantation

NASA Astrophysics Data System (ADS)

Singh, Jitendra Pal; Lim, Weon Cheol; Lee, Jihye; Song, Jonghan; Lee, Ik-Jae; Chae, Keun Hwa

2018-02-01

Present work is motivated to investigate the surface and local electronic structure modifications of MgO films implanted with Zn and Fe ions. MgO film was deposited using radio frequency sputtering method. Atomic force microscopy measurements exhibit morphological changes associated with implantation. Implantation of Fe and Zn ions leads to the reduction of co-ordination geometry of Mg2+ ions in host lattice. The effect is dominant at bulk of film rather than surface as the large concentration of implanted ions resides inside bulk. Moreover, the evidences of interaction among implanted ions and oxygen are not being observed using near edge fine structure measurements.

Dynamic mechanical control of local vacancies in NiO thin films

NASA Astrophysics Data System (ADS)

Seol, Daehee; Yang, Sang Mo; Jesse, Stephen; Choi, Minseok; Hwang, Inrok; Choi, Taekjib; Park, Bae Ho; Kalinin, Sergei V.; Kim, Yunseok

2018-07-01

The manipulation of local ionic behavior via external stimuli in oxide systems is of great interest because it can help in directly tuning material properties. Among external stimuli, mechanical force has attracted intriguing attention as novel stimulus for ionic modulation. Even though effectiveness of mechanical force on local ionic modulation has been validated in terms of static effect, its real-time i.e., dynamic, behavior under an application of the force is barely investigated in spite of its crucial impact on device performance such as force or pressure sensors. In this study, we explore dynamic ionic behavior modulated by mechanical force in NiO thin films using electrochemical strain microscopy (ESM). Ionically mediated ESM hysteresis loops were significantly varied under an application of mechanical force. Based on these results, we were able to investigate relative relationship between the force and voltage effects on ionic motion and, further, control effectively ionic behavior through combination of mechanical and electrical stimuli. Our results can provide comprehensive information on the effect of mechanical forces on ionic dynamics in ionic systems.

Dynamic mechanical control of local vacancies in NiO thin films.

PubMed

Seol, Daehee; Yang, Sang Mo; Jesse, Stephen; Choi, Minseok; Hwang, Inrok; Choi, Taekjib; Park, Bae Ho; Kalinin, Sergei V; Kim, Yunseok

2018-07-06

The manipulation of local ionic behavior via external stimuli in oxide systems is of great interest because it can help in directly tuning material properties. Among external stimuli, mechanical force has attracted intriguing attention as novel stimulus for ionic modulation. Even though effectiveness of mechanical force on local ionic modulation has been validated in terms of static effect, its real-time i.e., dynamic, behavior under an application of the force is barely investigated in spite of its crucial impact on device performance such as force or pressure sensors. In this study, we explore dynamic ionic behavior modulated by mechanical force in NiO thin films using electrochemical strain microscopy (ESM). Ionically mediated ESM hysteresis loops were significantly varied under an application of mechanical force. Based on these results, we were able to investigate relative relationship between the force and voltage effects on ionic motion and, further, control effectively ionic behavior through combination of mechanical and electrical stimuli. Our results can provide comprehensive information on the effect of mechanical forces on ionic dynamics in ionic systems.

The effective forces transmitted by high-speed, low-amplitude thoracic manipulation.

PubMed

Herzog, W; Kats, M; Symons, B

2001-10-01

Twenty asymptomatic volunteers each received three spinal manipulative treatments to the thoracic spine. The treatments consisted of a straight posterior-to-anterior high-speed, low-amplitude thrust to the transverse process of T3-T10 using a reinforced hypothenar contact. All treatments were given by a full-time practicing clinician with 3 years of experience. The primary objective of this study was to quantify local measures of loading applied by the clinician on the volunteers during spinal manipulative treatments and to compare these local measures of loading with previously described global measures. The sparse information on the mechanics of spinal manipulative treatments deals exclusively with global force or pressure measurements. On the basis of these global data, incorrect conclusions may be drawn about the beneficial effects of spinal manipulative therapy, the loading of internal structures, and the risks associated with these treatments. Twenty asymptomatic subjects each received three posterior-to-anterior, high-speed, low-amplitude spinal manipulative treatments to the transverse process of the thoracic spine. Total force, local force, contact area, peak pressure, and average pressure at the contact interface between clinician and subject were measured continuously by use of a thin, flexible pressure pad. Local and global measures of loading were compared and analyzed by use of nonparametric statistics (alpha = 0.01). The average peak total force was 238.2 N. The average peak local force over a target area of 25 mm2 was 5 N, indicating that global measures of loading vastly overestimate the local effective forces at the target site. The peak pressure point moved, on average, 9.8 mm during the course of the manipulation. To the authors' best knowledge, this is the first study to quantify local, effective measures of loading and compare them with the global measures typically used. The conclusions are limited because the study used a single clinician. The effective loading of specific target sites is much smaller than the global measures might suggest. This result occurs because as the forces during spinal manipulative treatment increase, so does the contact area; therefore, much of the total treatment force is taken up by non-target-specific tissues. Because of the vast discrepancy between the global and local measures of loading, it is suggested that risk-benefit assessments of high-speed, low-amplitude spinal manipulative treatments should be made, including local measures of loading. Finally, because theoretical approaches and the inverse dynamics approach can provide only global measures of loading, the results of such studies should be interpreted with caution.

Intelligence and Technology. Joint Force Quarterly, Issue 46, 3rd Quarter 2007

DTIC Science & Technology

2007-01-01

pioneering work of B.F. Skinner overcame this obstacle by embracing the notion of the “black box.” At the practical level, one does not need to see...possibilities here is the pioneering adaptation of the discipline of movement analysis described by Brenda Connors.19 In contrast to traditional profil- ing...unfamiliarity with the local geography and demography by arming them with informa- tion technology solutions, providing each Applying Law Enforcement

Policy Options and the U.S. Withdrawal from Iraq: An Analysis of the Way Ahead

DTIC Science & Technology

2009-08-01

Our specialists combine in-country experience, language skills, and the use of local primary-source data to produce empirically based work. All of...President Obama takes over, due to the supposed certitudes of the recently signed Status of Forces Agreement (SOFA); however, there are crucial decisions to...was ratified by the Iraqi parliament on November 27, 2008, and signed by the leaders of the two countries on December 14, 2008. This agreement

Biofilm formation and local electrostatic force characteristics of Escherichia coli O157:H7 observed by electrostatic force microscopy

NASA Astrophysics Data System (ADS)

Oh, Y. J.; Jo, W.; Yang, Y.; Park, S.

2007-04-01

The authors report growth media dependence of electrostatic force characteristics in Escherichia coli O157:H7 biofilm through local measurement by electrostatic force microscopy (EFM). The difference values of electrostatic interaction between the bacterial surface and the abiotic surface show an exponential decay behavior during biofilm development. In the EFM data, the biofilm in the low nutrient media shows a faster decay than the biofilm in the rich media. The surface potential in the bacterial cells was changed from 957to149mV. Local characterization of extracellular materials extracted from the bacteria reveals the progress of the biofilm formation and functional complexities.

High-velocity deformation of Al0.3CoCrFeNi high-entropy alloy: Remarkable resistance to shear failure

PubMed Central

Li, Z.; Zhao, S.; Diao, H.; Liaw, P. K.; Meyers, M. A.

2017-01-01

The mechanical behavior of a single phase (fcc) Al0.3CoCrFeNi high-entropy alloy (HEA) was studied in the low and high strain-rate regimes. The combination of multiple strengthening mechanisms such as solid solution hardening, forest dislocation hardening, as well as mechanical twinning leads to a high work hardening rate, which is significantly larger than that for Al and is retained in the dynamic regime. The resistance to shear localization was studied by dynamically-loading hat-shaped specimens to induce forced shear localization. However, no adiabatic shear band could be observed. It is therefore proposed that the excellent strain hardening ability gives rise to remarkable resistance to shear localization, which makes this material an excellent candidate for penetration protection applications such as armors. PMID:28210000

Separation of traveling and standing waves in a finite dispersive string with partial or continuous viscoelastic foundation

NASA Astrophysics Data System (ADS)

Cheng, Xiangle; Blanchard, Antoine; Tan, Chin An; Lu, Huancai; Bergman, Lawrence A.; McFarland, D. Michael; Vakakis, Alexander F.

2017-12-01

The free and forced vibrations of a linear string with a local spring-damper on a partial elastic foundation, as well as a linear string on a viscoelastic foundation conceptualized as a continuous distribution of springs and dampers, are studied in this paper. Exact, analytical results are obtained for the free and forced response to a harmonic excitation applied at one end of the string. Relations between mode complexity and energy confinement with the dispersion in the string system are examined for the steady-state forced vibration, and numerical methods are applied to simulate the transient evolution of energy propagation. Eigenvalue loci veering and normal mode localization are observed for weakly coupled subsystems, when the foundation stiffness is sufficiently large, for both the spatially symmetric and asymmetric systems. The forced vibration results show that nonproportional damping-induced mode complexity, for which there are co-existing regions of purely traveling waves and standing waves, is attainable for the dispersive string system. However, this wave transition phenomenon depends strongly on the location of the attached discrete spring-damper relative to the foundation and whether the excitation frequency Ω is above or below the cutoff frequency ωc. When Ω<ωc, the wave transition cannot be attained for a string on an elastic foundation, but is possible if the string is on a viscoelastic foundation. Although this study is primarily formulated for a harmonic boundary excitation at one end of the string, generalization of the mode complexity can be deduced for the steady-state forced response of the string-foundation system to synchronous end excitations and is confirmed numerically. This work represents a novel study to understand the wave transitions in a dispersive structural system and lays the groundwork for potentially effective passive vibration control strategies.

The limits of behaviour change theory: condom use and contexts of HIV risk in the Kolkata sex industry.

PubMed

Evans, Catrin; Lambert, Helen

2008-01-01

This paper uses ethnographic data from a sex workers' HIV project in India to consider the appropriateness of individual, social/group and structural theories of health behaviour when applied to HIV-prevention initiatives. Existing theories are critiqued for their modernist representation of behaviour as determined by individual rational decision-making processes or by external structural forces, with inadequate recognition being given to the roles that human agency, subjective meaning and local context play in everyday actions. Analysis of sex workers' accounts of their sexual practices suggests that existing theories of health behaviour can only partially account for sexual behaviour change retrospectively and that they have limited predictive value with respect to the outcomes of individual sexual encounters. Our data show that these outcomes were, in fact, highly context dependent, while possibilities for action were ultimately strongly constrained by structural forces. Findings suggest that interventions need to adopt an integrated, structurally-oriented approach for promoting safer sexual practices in sex work settings. Recognising that no one model of health behaviour is likely to be adequate in explaining or predicting behaviour change encourages responsiveness to local people's agency, recognises the different (health- and non-health-related) registers of risk with which people operate and encourages flexibility according to local contingencies and contexts.

A Finite-Element Method Model of Soft Tissue Response to Impulsive Acoustic Radiation Force

PubMed Central

Palmeri, Mark L.; Sharma, Amy C.; Bouchard, Richard R.; Nightingale, Roger W.; Nightingale, Kathryn R

2010-01-01

Several groups are studying acoustic radiation force and its ability to image the mechanical properties of tissue. Acoustic radiation force impulse (ARFI) imaging is one modality using standard diagnostic ultrasound scanners to generate localized, impulsive, acoustic radiation forces in tissue. The dynamic response of tissue is measured via conventional ultrasonic speckle-tracking methods and provides information about the mechanical properties of tissue. A finite-element method (FEM) model has been developed that simulates the dynamic response of tissues, with and without spherical inclusions, to an impulsive acoustic radiation force excitation from a linear array transducer. These FEM models were validated with calibrated phantoms. Shear wave speed, and therefore elasticity, dictates tissue relaxation following ARFI excitation, but Poisson’s ratio and density do not significantly alter tissue relaxation rates. Increased acoustic attenuation in tissue increases the relative amount of tissue displacement in the near field compared with the focal depth, but relaxation rates are not altered. Applications of this model include improving image quality, and distilling material and structural information from tissue’s dynamic response to ARFI excitation. Future work on these models includes incorporation of viscous material properties and modeling the ultrasonic tracking of displaced scatterers. PMID:16382621

Can a minimalist model of wind forced baroclinic Rossby waves produce reasonable results?

NASA Astrophysics Data System (ADS)

Watanabe, Wandrey B.; Polito, Paulo S.; da Silveira, Ilson C. A.

2016-04-01

The linear theory predicts that Rossby waves are the large scale mechanism of adjustment to perturbations of the geophysical fluid. Satellite measurements of sea level anomaly (SLA) provided sturdy evidence of the existence of these waves. Recent studies suggest that the variability in the altimeter records is mostly due to mesoscale nonlinear eddies and challenges the original interpretation of westward propagating features as Rossby waves. The objective of this work is to test whether a classic linear dynamic model is a reasonable explanation for the observed SLA. A linear-reduced gravity non-dispersive Rossby wave model is used to estimate the SLA forced by direct and remote wind stress. Correlations between model results and observations are up to 0.88. The best agreement is in the tropical region of all ocean basins. These correlations decrease towards insignificance in mid-latitudes. The relative contributions of eastern boundary (remote) forcing and local wind forcing in the generation of Rossby waves are also estimated and suggest that the main wave forming mechanism is the remote forcing. Results suggest that linear long baroclinic Rossby wave dynamics explain a significant part of the SLA annual variability at least in the tropical oceans.

U.S. Department of Energy, Office of Legacy Management Program Update, April-June 2009

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2009-04-01

Welcome to the April-June 2009 issue of the U.S. Department of Energy (DOE) Office of Legacy Management (LM) Program Update. This publication is designed to provide a status of activities within LM. The Legacy Management goals are: (1) Protect human health and the environment through effective and efficient long-term surveillance and maintenance - This goal highlights DOE's responsibility to ensure long-term protection of people, the environment, and the integrity of engineered remedies and monitoring systems. (2) Preserve, protect, and make accessible legacy records and information - This goal recognizes LM's commitment to successfully manage records, information, and archives of legacymore » sites under its authority. (3) Support an effective and efficient work force structured to accomplish Departmental missions and assure continuity of contractor worker pension and medical benefits - This goal recognizes DOE's commitment to its contracted work force and the consistent management of pension and health benefits. As sites continue to close, DOE faces the challenges of managing pension plan and health benefits liability. (4) Manage legacy land and assets, emphasizing protective real and personal property reuse and disposition - This goal recognizes a DOE need for local collaborative management of legacy assets, including coordinating land use planning, personal property disposition to community reuse organizations, and protecting heritage resources (natural, cultural, and historical). (5) Improve program effectiveness through sound management - This goal recognizes that LM's goals cannot be attained efficiently unless the federal and contractor work force is motivated to meet requirements and work toward continuous performance improvement.« less

Cellular Force Microscopy for in Vivo Measurements of Plant Tissue Mechanics1[W][OA

PubMed Central

Routier-Kierzkowska, Anne-Lise; Weber, Alain; Kochova, Petra; Felekis, Dimitris; Nelson, Bradley J.; Kuhlemeier, Cris; Smith, Richard S.

2012-01-01

Although growth and morphogenesis are controlled by genetics, physical shape change in plant tissue results from a balance between cell wall loosening and intracellular pressure. Despite recent work demonstrating a role for mechanical signals in morphogenesis, precise measurement of mechanical properties at the individual cell level remains a technical challenge. To address this challenge, we have developed cellular force microscopy (CFM), which combines the versatility of classical microindentation techniques with the high automation and resolution approaching that of atomic force microscopy. CFM’s large range of forces provides the possibility to map the apparent stiffness of both plasmolyzed and turgid tissue as well as to perform micropuncture of cells using very high stresses. CFM experiments reveal that, within a tissue, local stiffness measurements can vary with the level of turgor pressure in an unexpected way. Altogether, our results highlight the importance of detailed physically based simulations for the interpretation of microindentation results. CFM’s ability to be used both to assess and manipulate tissue mechanics makes it a method of choice to unravel the feedbacks between mechanics, genetics, and morphogenesis. PMID:22353572

Resistive thrust production can be as crucial as added mass mechanisms for inertial undulatory swimmers

NASA Astrophysics Data System (ADS)

Piñeirua, M.; Godoy-Diana, R.; Thiria, B.

2015-08-01

In this Rapid Communication, we address a crucial point regarding the description of moderate to high Reynolds numbers aquatic swimmers. For decades, swimming animals have been classified in two different families of propulsive mechanisms based on the Reynolds number: the resistive swimmers, using local friction to produce the necessary thrust force for locomotion at low Reynolds number, and the reactive swimmers, lying in the high Reynolds range, and using added mass acceleration (described by perfect fluid theory). However, inertial swimmers are also systems that dissipate energy, due to their finite size, therefore involving strong resistive contributions, even for high Reynolds numbers. Using a complete model for the hydrodynamic forces, involving both reactive and resistive contributions, we revisit here the physical mechanisms responsible for the thrust production of such swimmers. We show, for instance, that the resistive part of the force balance is as crucial as added mass effects in the modeling of the thrust force, especially for elongated species. The conclusions brought by this work may have significant contributions to the understanding of complex swimming mechanisms, especially for the future design of artificial swimmers.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Park, Jong-Kyu; Logan, Nikolas C.

Toroidal torque is one of the most important consequences of non-axisymmetric fields in tokamaks. The well-known neoclassical toroidal viscosity (NTV) is due to the second-order toroidal force from anisotropic pressure tensor in the presence of these asymmetries. This work shows that the first-order toroidal force originating from the same anisotropic pressure tensor, despite having no flux surface average, can significantly modify the local perturbed force balance and thus must be included in perturbed equilibrium self-consistent with NTV. The force operator with an anisotropic pressure tensor is not self-adjoint when the NTV torque is finite and thus is solved directly formore » each component. This approach yields a modified, non-self-adjoint Euler-Lagrange equation that can be solved using a variety of common drift-kinetic models in generalized tokamak geometry. The resulting energy and torque integral provides a unique way to construct a torque response matrix, which contains all the information of self-consistent NTV torque profiles obtainable by applying non-axisymmetric fields to the plasma. This torque response matrix can then be used to systematically optimize non-axisymmetric field distributions for desired NTV profiles. Published by AIP Publishing.« less

Do radiative feedbacks depend on the structure and type of climate forcing, or only on the spatial pattern of surface temperature change?

NASA Astrophysics Data System (ADS)

Haugstad, A.; Battisti, D. S.; Armour, K.

2016-12-01

Earth's climate sensitivity depends critically on the strength of radiative feedbacks linking surface warming to changes in top-of-atmosphere (TOA) radiation. Many studies use a simplistic idea of radiative feedbacks, either by treating them as global mean quantities, or by assuming they can be defined uniquely by geographic location and thus that TOA radiative response depends only on local surface warming. For example, a uniform increase in sea-surface temperature has been widely used as a surrogate for global warming (e.g., Cess et al 1990 and the CMIP 'aqua4k' simulations), with the assumption that this produces the same radiative feedbacks as those arising from a doubling of carbon dioxide - even though the spatial patterns of warming differ. However, evidence suggests that these assumptions are not valid, and local feedbacks may be integrally dependent on the structure of warming or type of climate forcing applied (Rose et al 2014). This study thus investigates the following questions: to what extent do local feedbacks depend on the structure and type of forcing applied? And, to what extent do they depend on the pattern of surface temperature change induced by that forcing? Using an idealized framework of an aquaplanet atmosphere-only model, we show that radiative feedbacks are indeed dependent on the large scale structure of warming and type of forcing applied. For example, the climate responds very differently to two forcings of equal global magnitude but applied in different global regions; the pattern of local feedbacks arising from uniform warming are not the same as that arising from polar amplified warming; and the same local feedbacks can be induced by distinct forcing patterns, provided that they produce the same pattern of surface temperature change. These findings suggest that the so-called `efficacies' of climate forcings can be understood simply in terms of how local feedbacks depend on the temperature patterns they induce.

Stress induced magnetic-domain evolution in magnetoelectric composites

NASA Astrophysics Data System (ADS)

Trivedi, Harsh; Shvartsman, Vladimir V.; Lupascu, Doru C.; Medeiros, Marco S. A.; Pullar, Robert C.

2018-06-01

Local observation of the stress mediated magnetoelectric (ME) effect in composites has gained a great deal of interest over the last decades. However, there is an apparent lack of rigorous methods for a quantitative characterization of the ME effect at the local scale, especially in polycrystalline microstructures. In the present work, we address this issue by locally probing the surface magnetic state of barium titante–hexagonal barium ferrite (BaTiO3–BaFe12O19) ceramic composites using magnetic force microscopy (MFM). The effect of the piezoelectrically induced local stress on the magnetostrictive component (BaFe12O19, BaM) was observed in the form of the evolution of the magnetic domains. The local piezoelectric stress was induced by applying a voltage to the neighboring BaTiO3 grains, using a conductive atomic force microscopy tip. The resulting stochastic evolution of magnetic domains was studied in the context of the induced magnetoelastic anisotropy. In order to overcome the ambiguity in the domain changes observed by MFM, certain generalizations about the observed MFM contrast are put forward, followed by application of an algorithm for extracting the average micromagnetic changes. An average change in domain wall thickness of 50 nm was extracted, giving a lower limit on the corresponding induced magnetoelastic anisotropy energy. Furthermore, we demonstrate that this induced magnetomechanical energy is approximately equal to the K1 magnetocrystalline anisotropy constant of BaM, and compare it with a modeled value of applied elastic energy density. The comparison allowed us to judge the quality of the interfaces in the composite system, by roughly gauging the energy conversion ratio.

Local conductance: A means to extract polarization and depolarizing fields near domain walls in ferroelectrics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Douglas, A. M.; Kumar, A.; Gregg, J. M.

Conducting atomic force microscopy images of bulk semiconducting BaTiO{sub 3} surfaces show clear stripe domain contrast. High local conductance correlates with strong out-of-plane polarization (mapped independently using piezoresponse force microscopy), and current-voltage characteristics are consistent with dipole-induced alterations in Schottky barriers at the metallic tip-ferroelectric interface. Indeed, analyzing current-voltage data in terms of established Schottky barrier models allows relative variations in the surface polarization, and hence the local domain structure, to be determined. Fitting also reveals the signature of surface-related depolarizing fields concentrated near domain walls. Domain information obtained from mapping local conductance appears to be more surface-sensitive than thatmore » from piezoresponse force microscopy. In the right materials systems, local current mapping could therefore represent a useful complementary technique for evaluating polarization and local electric fields with nanoscale resolution.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kalligiannaki, Evangelia, E-mail: ekalligian@tem.uoc.gr; Harmandaris, Vagelis, E-mail: harman@uoc.gr; Institute of Applied and Computational Mathematics

Using the probabilistic language of conditional expectations, we reformulate the force matching method for coarse-graining of molecular systems as a projection onto spaces of coarse observables. A practical outcome of this probabilistic description is the link of the force matching method with thermodynamic integration. This connection provides a way to systematically construct a local mean force and to optimally approximate the potential of mean force through force matching. We introduce a generalized force matching condition for the local mean force in the sense that allows the approximation of the potential of mean force under both linear and non-linear coarse grainingmore » mappings (e.g., reaction coordinates, end-to-end length of chains). Furthermore, we study the equivalence of force matching with relative entropy minimization which we derive for general non-linear coarse graining maps. We present in detail the generalized force matching condition through applications to specific examples in molecular systems.« less

Scanning Probe Microscopy of Organic Solar Cells

NASA Astrophysics Data System (ADS)

Reid, Obadiah G.

Nanostructured composites of organic semiconductors are a promising class of materials for the manufacture of low-cost solar cells. Understanding how the nanoscale morphology of these materials affects their efficiency as solar energy harvesters is crucial to their eventual potential for large-scale deployment for primary power generation. In this thesis we describe the use of optoelectronic scanning-probe based microscopy methods to study this efficiency-structure relationship with nanoscale resolution. In particular, our objective is to make spatially resolved measurements of each step in the power conversion process from photons to an electric current, including charge generation, transport, and recombination processes, and correlate them with local device structure. We have achieved two aims in this work: first, to develop and apply novel electrically sensitive scanning probe microscopy experiments to study the optoelectronic materials and processes discussed above; and second, to deepen our understanding of the physics underpinning our experimental techniques. In the first case, we have applied conductive-, and photoconductive atomic force (cAFM & pcAFM) microscopy to measure both local photocurrent collection and dark charge transport properties in a variety of model and novel organic solar cell composites, including polymer/fullerene blends, and polymer-nanowire/fullerene blends, finding that local heterogeneity is the rule, and that improvements in the uniformity of specific beneficial nanostructures could lead to large increases in efficiency. We have used scanning Kelvin probe microscopy (SKPM) and time resolved-electrostatic force microscopy (trEFM) to characterize all-polymer blends, quantifying their sensitivity to photochemical degradation and the subsequent formation of local charge traps. We find that while trEFM provides a sensitive measure of local quantum efficiency, SKPM is generally unsuited to measurements of efficiency, less sensitive than trEFM, and of greater utility in identifying local changes in steady-state charge density that can be associated with charge trapping. In the second case, we have developed a new understanding of charge transport between a sharp AFM tip and planar substrates applicable to conductive and photoconductive atomic force microscopy, and shown that hole-only transport characteristics can be easily obtained including quantitative values of the charge carrier mobility. Finally, we have shown that intensity-dependent photoconductive atomic force microscopy measurements can be used to infer the 3D structure of organic photovoltaic materials, and gained new insight into the influence vertical composition of the these devices can have on their open-circuit voltage and its intensity dependence.

America's Changing Work Force: Statistics in Brief.

ERIC Educational Resources Information Center

American Association of Retired Persons, Washington, DC.

This booklet provides information about the demographics of the changing work force. It offers an at-a-glance profile of workers age 45 and older and considers likely changes in the work force of the future. The document includes topics such as the composition of the work force of today and tomorrow by age and sex, labor force participation rates,…

Interference of Locally Forced Internal Waves in Non-Uniform Stratifications

NASA Astrophysics Data System (ADS)

Supekar, Rohit; Peacock, Thomas

2017-11-01

Several studies have investigated the effect of constructive or destructive interference on the transmission of internal waves propagating through non-uniform stratifications. Such studies have been performed for internal waves that are spatiotemporally harmonic. To understand the effect of localization, we perform a theoretical and experimental study of the transmission of two-dimensional internal waves that are generated by a spatiotemporally localized boundary forcing. This is done by considering an idealized problem and applying a weakly viscous semi-analytic linear model. Parametric studies using this model show that localization leads to the disappearance of transmission peaks and troughs that would otherwise be present for a harmonic forcing. Laboratory experiments that we perform provide a clear indication of this physical effect. Based on the group velocity and angle of propagation of the internal waves, a practical criteria that assesses when the transmission peaks or troughs are evident, is obtained. It is found that there is a significant difference in the predicted energy transfer due to a harmonic and non-harmonic forcing which has direct implications to various physical forcings such as a storm over the ocean.

Linking initial microstructure and local response during quasistatic granular compaction

DOE PAGES

Hurley, R. C.; Lind, J.; Pagan, D. C.; ...

2017-07-24

In this study, we performed experiments combining three-dimensional x-ray diffraction and x-ray computed tomography to explore the relationship between microstructure and local force and strain during quasistatic granular compaction. We found that initial void space around a grain and contact coordination number before compaction can be used to predict regions vulnerable to above-average local force and strain at later stages of compaction. We also found correlations between void space around a grain and coordination number, and between grain stress and maximum interparticle force, at all stages of compaction. Finally, we observed grains that fracture to have an above-average initial localmore » void space and a below-average initial coordination number. In conclusion, our findings provide (1) a detailed description of microstructure evolution during quasistatic granular compaction, (2) an approach for identifying regions vulnerable to large values of strain and interparticle force, and (3) methods for identifying regions of a material with large interparticle forces and coordination numbers from measurements of grain stress and local porosity.« less

Circular flow patterns induced by ciliary activity in reconstituted human bronchial epithelium

NASA Astrophysics Data System (ADS)

Viallat, Annie; Khelloufi, Kamel; Gras, Delphine; Chanez, Pascal; Aix Marseille Univ., CNRS, CINaM, Marseille, France Team; Aix Marseille Univ., CNRS, Inserm, LAI, Marseille, France Team

2016-11-01

Mucociliary clearance is the transport at the surface of airways of a complex fluid layer, the mucus, moved by the beats of microscopic cilia present on epithelial ciliated cells. We explored the coupling between the spatial organisation and the activity of cilia and the transport of surface fluids on reconstituted cultures of human bronchial epithelium at air-liquid interface, obtained by human biopsies. We reveal the existence of stable local circular surface flow patterns of mucus or Newtonian fluid at the epithelium surface. We find a power law over more than 3 orders of magnitude showing that the average ciliated cell density controls the size of these flow patterns, and, therefore the distance over which mucus can be transported. We show that these circular flow patterns result from the radial linear increase of the local propelling forces (due to ciliary beats) on each flow domain. This linear increase of local forces is induced by a fine self-regulation of both cilia density and orientation of ciliary beats. Local flow domains grow and merge during ciliogenesis to provide macroscopic mucus transport. This is possible only when the viscoelastic mucus continuously exerts a shear stress on beating cilia, revealing a mechanosensitive function of cilia. M. K. Khelloufi thanks the society MedBioMed for financial support. This work was supported by the ANR MUCOCIL project, Grant ANR-13-BSV5-0015 of the French Agence Nationale de la Recherche.

What do Afghans Want from the Police? Views from Helmand Province

DTIC Science & Technology

2012-01-01

AUTHOR(S) Norman, Catherine 5d PROJECT NUMBER R0148 5e. TASK NUMBER W053 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS...ES) Center for Naval Analyses 4825 Mark Center Drive Alexandria, VA 22311-1850 8. PERFORMING ORGANIZATION REPORT NUMBER D0026181.A2 9... organizations are expected to trump local values. For instance, when a person joins a city police force, he or she is expected to sub- ordinate the

Policy Options and the U.S. Withdrawal from Iraq: An Analysis of the Way Ahead

DTIC Science & Technology

2009-02-01

specialists combine in-country experience, language skills, and the use of local primary-source data to produce empirically based work. All of our...due to the supposed certitudes of the recently signed Status of Forces Agreement (SOFA); however, there are crucial decisions to be made, and made...Iraqi parliament on November 27, 2008, and signed by the leaders of the two countries on December 14, 2008. This agreement replaces the UN mandate on

Policy Options and the U.S. Withdrawal from Iraq: An Analysis of the Way Ahead

DTIC Science & Technology

2009-07-01

country experience, language skills, and the use of local primary-source data to produce empirically based work. All of our analysts have advanced...the supposed certitudes of the recently signed Status of Forces Agreement (SOFA); however, there are crucial decisions to be made, and made quickly...parliament on November 27, 2008, and signed by the leaders of the two countries on December 14, 2008. This agreement replaces the UN mandate on the first

Evaluating meteo marine climatic model inputs for the investigation of coastal hydrodynamics

NASA Astrophysics Data System (ADS)

Bellafiore, D.; Bucchignani, E.; Umgiesser, G.

2010-09-01

One of the major aspects discussed in the recent works on climate change is how to provide information from the global scale to the local one. In fact the influence of sea level rise and changes in the meteorological conditions due to climate change in strategic areas like the coastal zone is at the base of the well known mitigation and risk assessment plans. The investigation of the coastal zone hydrodynamics, from a modeling point of view, has been the field for the connection between hydraulic models and ocean models and, in terms of process studies, finite element models have demonstrated their suitability in the reproduction of complex coastal morphology and in the capability to reproduce different spatial scale hydrodynamic processes. In this work the connection between two different model families, the climate models and the hydrodynamic models usually implemented for process studies, is tested. Together, they can be the most suitable tool for the investigation of climate change on coastal systems. A finite element model, SHYFEM (Shallow water Hydrodynamic Finite Element Model), is implemented on the Adriatic Sea, to investigate the effect of wind forcing datasets produced by different downscaling from global climate models in terms of surge and its coastal effects. The wind datasets are produced by the regional climate model COSMO-CLM (CIRA), and by EBU-POM model (Belgrade University), both downscaling from ECHAM4. As a first step the downscaled wind datasets, that have different spatial resolutions, has been analyzed for the period 1960-1990 to compare what is their capability to reproduce the measured wind statistics in the coastal zone in front of the Venice Lagoon. The particularity of the Adriatic Sea meteo climate is connected with the influence of the orography in the strengthening of winds like Bora, from North-East. The increase in spatial resolution permits the more resolved wind dataset to better reproduce meteorology and to provide a more realistic forcing for hydrodynamic simulations. After this analysis, effects on water level variations, under different wind forcing, has been analyzed to define what is the local effect on sea level changes in the coastal area of the North Adriatic. Surge statistics produced from different climate model forcings for the IPCC A1B scenario have been studied to provide local information on climate change effects on coastal hydrodynamics due to meteorological effect. This typology of application has been considered a suitable tool for coastal management and can be considered a study field that will increase its importance in the more general investigation on scale interaction processes as the effects of global scale climate phenomena on local areas.

Coarse-grained Simulations of Sugar Transport and Conformational Changes of Lactose Permease

NASA Astrophysics Data System (ADS)

Liu, Jin; Jewel, S. M. Yead; Dutta, Prashanta

2016-11-01

Escherichia coli lactose permease (LacY) actively transports lactose and other galactosides across cell membranes through lactose/H+ symport process. Lactose/H+ symport is a highly complex process that involves sugar translocation, H+ transfer, as well as large-scale protein conformational changes. The complete picture of lactose/H+ symport is largely unclear due to the complexity and multiscale nature of the process. In this work, we develop the force field for sugar molecules compatible with PACE, a hybrid and coarse-grained force field that couples the united-atom protein models with the coarse-grained MARTINI water/lipid. After validation, we implement the new force field to investigate the transport of a β-D-galactopyranosyl-1-thio- β-D-galactopyranoside (TDG) molecule across a wild-type LacY during lactose/H+ symport process. Results show that the local interactions between TDG and LacY at the binding pocket are consistent with the X-ray experiment. Protonation of Glu325 stabilizes the TDG and inward-facing conformation of LacY. Protonation of Glu269 induces a dramatic protein structural reorganization and causes the expulsion of TDG from LacY to both sides of the membrane. The structural changes occur primarily in the N-terminal domain of LacY. This work is supported by NSF Grants: CBET-1250107 and CBET -1604211.

Spatial localization in heterogeneous systems

NASA Astrophysics Data System (ADS)

Kao, Hsien-Ching; Beaume, Cédric; Knobloch, Edgar

2014-01-01

We study spatial localization in the generalized Swift-Hohenberg equation with either quadratic-cubic or cubic-quintic nonlinearity subject to spatially heterogeneous forcing. Different types of forcing (sinusoidal or Gaussian) with different spatial scales are considered and the corresponding localized snaking structures are computed. The results indicate that spatial heterogeneity exerts a significant influence on the location of spatially localized structures in both parameter space and physical space, and on their stability properties. The results are expected to assist in the interpretation of experiments on localized structures where departures from spatial homogeneity are generally unavoidable.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Mi; University of Chinese Academy of Sciences, Beijing 100049; Liu, Lianqing, E-mail: lqliu@sia.cn

Highlights: •Nanoscale cellular ultra-structures of macrophages were observed. •The binding affinities of FcγRs were measured directly on macrophages. •The nanoscale distributions of FcγRs were mapped on macrophages. -- Abstract: Fc gamma receptors (FcγR), widely expressed on effector cells (e.g., NK cells, macrophages), play an important role in clinical cancer immunotherapy. The binding of FcγRs to the Fc portions of antibodies that are attached to the target cells can activate the antibody-dependent cell-mediated cytotoxicity (ADCC) killing mechanism which leads to the lysis of target cells. In this work, we used atomic force microscopy (AFM) to observe the cellular ultra-structures and measuremore » the biophysical properties (affinity and distribution) of FcγRs on single macrophages in aqueous environments. AFM imaging was used to obtain the topographies of macrophages, revealing the nanoscale cellular fine structures. For molecular interaction recognition, antibody molecules were attached onto AFM tips via a heterobifunctional polyethylene glycol (PEG) crosslinker. With AFM single-molecule force spectroscopy, the binding affinities of FcγRs were quantitatively measured on single macrophages. Adhesion force mapping method was used to localize the FcγRs, revealing the nanoscale distribution of FcγRs on local areas of macrophages. The experimental results can improve our understanding of FcγRs on macrophages; the established approach will facilitate further research on physiological activities involved in antibody-based immunotherapy.« less

Relating normal vibrational modes to local vibrational modes with the help of an adiabatic connection scheme

NASA Astrophysics Data System (ADS)

Zou, Wenli; Kalescky, Robert; Kraka, Elfi; Cremer, Dieter

2012-08-01

Information on the electronic structure of a molecule and its chemical bonds is encoded in the molecular normal vibrational modes. However, normal vibrational modes result from a coupling of local vibrational modes, which means that only the latter can provide detailed insight into bonding and other structural features. In this work, it is proven that the adiabatic internal coordinate vibrational modes of Konkoli and Cremer [Int. J. Quantum Chem. 67, 29 (1998)], 10.1002/(SICI)1097-461X(1998)67:1<29::AID-QUA3>3.0.CO;2-0 represent a unique set of local modes that is directly related to the normal vibrational modes. The missing link between these two sets of modes are the compliance constants of Decius, which turn out to be the reciprocals of the local mode force constants of Konkoli and Cremer. Using the compliance constants matrix, the local mode frequencies of any molecule can be converted into its normal mode frequencies with the help of an adiabatic connection scheme that defines the coupling of the local modes in terms of coupling frequencies and reveals how avoided crossings between the local modes lead to changes in the character of the normal modes.

Supervisory autonomous local-remote control system design: Near-term and far-term applications

NASA Technical Reports Server (NTRS)

Zimmerman, Wayne; Backes, Paul

1993-01-01

The JPL Supervisory Telerobotics Laboratory (STELER) has developed a unique local-remote robot control architecture which enables management of intermittent bus latencies and communication delays such as those expected for ground-remote operation of Space Station robotic systems via the TDRSS communication platform. At the local site, the operator updates the work site world model using stereo video feedback and a model overlay/fitting algorithm which outputs the location and orientation of the object in free space. That information is relayed to the robot User Macro Interface (UMI) to enable programming of the robot control macros. The operator can then employ either manual teleoperation, shared control, or supervised autonomous control to manipulate the object under any degree of time-delay. The remote site performs the closed loop force/torque control, task monitoring, and reflex action. This paper describes the STELER local-remote robot control system, and further describes the near-term planned Space Station applications, along with potential far-term applications such as telescience, autonomous docking, and Lunar/Mars rovers.

Humidity Effect on Nanoscale Electrochemistry in Solid Silver Ion Conductors and the Dual Nature of Its Locality

DOE PAGES

Yang, Sangmo; Strelcov, Evgheni; Paranthaman, Mariappan Parans; ...

2015-01-07

Scanning probe microscopy (SPM) is a powerful tool to investigate electrochemistry in nanoscale volumes. While most SPM-based studies have focused on reactions at the tip-surface junction, charge and mass conservation requires coupled and intrinsically non-local cathodic and anodic processes that can be significantly affected by ambient humidity. Here, we explore the role of water in both cathodic and anodic processes, associated charge transport, and topographic volume changes depending on the polarity of tip bias. The first-order reversal curve current-voltage technique combined with simultaneous detection of the sample topography, referred to as FORC-IVz, was applied to a silver solid ion conductor.more » We found that the protons generated from water affect silver ionic conduction, silver particle formation and dissolution, and mechanical integrity of the material. This work highlights the dual nature (simultaneously local and non-local) of electrochemical SPM studies, which should be considered for comprehensive understanding of nanoscale electrochemistry.« less

Combination of a total free forearm flap and a sensate local flap for preservation of the shoulder girdle in massive, nonreplantable upper extremity injuries.

PubMed

Jakubietz, Rafael G; Jakubietz, Michael G; Kloss, Danni F; Gruenert, Joerg G

2009-02-01

After massive upper extremity injuries, prosthetic use might be complicated by the formation of pressure ulcerations. Especially the coverage with insensate free flaps may predispose the patient for developing chronic ulcerations when using an upper extremity prosthesis. This complication may be reduced when sensate local flaps are used to cover bony prominences. A new operative technique is described. Immediate sensate soft tissue coverage improves prosthetic fitting. Successful manipulation of the prosthesis can be quickly achieved with a decreased risk for pressure ulceration. This challenging procedure helps to achieve durable and sensate coverage of bony prominences. The use of local sensate tissue to cover bony prominences reduces the risk for pressure ulceration when wearing a prosthesis. Areas where prosthetic use causes only low pressure and shearing forces are adequately covered with free flaps. Immediate sensibility of local flaps allows prosthetic fitting and use as soon as wound healing has occurred. Return to work is thus expedited.

Local light-induced magnetization using nanodots and chiral molecules.

PubMed

Dor, Oren Ben; Morali, Noam; Yochelis, Shira; Baczewski, Lech Tomasz; Paltiel, Yossi

2014-11-12

With the increasing demand for miniaturization, nanostructures are likely to become the primary components of future integrated circuits. Different approaches are being pursued toward achieving efficient electronics, among which are spin electronics devices (spintronics). In principle, the application of spintronics should result in reducing the power consumption of electronic devices. Recently a new, promising, effective approach for spintronics has emerged, using spin selectivity in electron transport through chiral molecules. In this work, using chiral molecules and nanocrystals, we achieve local spin-based magnetization generated optically at ambient temperatures. Through the chiral layer, a spin torque can be transferred without permanent charge transfer from the nanocrystals to a thin ferromagnetic layer, creating local perpendicular magnetization. We used Hall sensor configuration and atomic force microscopy (AFM) to measure the induced local magnetization. At low temperatures, anomalous spin Hall effects were measured using a thin Ni layer. The results may lead to optically controlled spintronics logic devices that will enable low power consumption, high density, and cheap fabrication.

Transonic and supersonic ground effect aerodynamics

NASA Astrophysics Data System (ADS)

Doig, G.

2014-08-01

A review of recent and historical work in the field of transonic and supersonic ground effect aerodynamics has been conducted, focussing on applied research on wings and aircraft, present and future ground transportation, projectiles, rocket sleds and other related bodies which travel in close ground proximity in the compressible regime. Methods for ground testing are described and evaluated, noting that wind tunnel testing is best performed with a symmetry model in the absence of a moving ground; sled or rail testing is ultimately preferable, though considerably more expensive. Findings are reported on shock-related ground influence on aerodynamic forces and moments in and accelerating through the transonic regime - where force reversals and the early onset of local supersonic flow is prevalent - as well as more predictable behaviours in fully supersonic to hypersonic ground effect flows.

Nanomechanical characterization of nanostructured bainitic steel: Peak Force Microscopy and Nanoindentation with AFM.

PubMed

Morales-Rivas, Lucia; González-Orive, Alejandro; Garcia-Mateo, Carlos; Hernández-Creus, Alberto; Caballero, Francisca G; Vázquez, Luis

2015-11-25

The full understanding of the deformation mechanisms in nanostructured bainite requires the local characterization of its mechanical properties, which are expected to change from one phase, bainitic ferrite, to another, austenite. This study becomes a challenging process due to the bainitic nanostructured nature and high Young's modulus. In this work, we have carried out such study by means of the combination of AFM-based techniques, such as nanoindentation and Peak Force Quantitative Nanomechanical Mapping (PF-QNM) measurements. We have addressed critically the limits and advantages of these techniques and been able to measure some elastoplastic parameters of both phases. Specifically, we have analyzed by PF-QNM two nanostructured bainitic steels, with a finer and a coarser structure, and found that both phases have a similar Young's modulus.

Problems associated with reaction mass actuators used in conjunction with LQG control on the Mini-Mast

NASA Technical Reports Server (NTRS)

Ghosh, D.; Montgomery, R. C.

1987-01-01

The work being done at NASA LaRC on developing control laws for the Mini-Mast experimental facility is reviewed with particular attention given to the problems associated with the stroke limit of the reaction mass actuators used in conjunction with the LQG control. An algorithm for converting the force commands of the LQG algorithm into position command for the reaction mass devices is described. It is shown that the position command can be used as an input to a local controller so that the relative position of the reaction mass would track the commanded relative position. The stabilization of the integration scheme makes it possible to avoid the position drift arising in the direct double integration method of converting force commands to position commands.

The moon-Earth system...As a vacuum gravity energy machine? A Hint about the Nature of Universal Gravity that May Have Been Overlooked

NASA Astrophysics Data System (ADS)

Masters, Roy

2011-10-01

We revisit the theories describing the moon raising the tides by virtue of pull gravity combined with the moon's centripetal angular momentum. We show that if gravity is considered as the attractive interaction between individual bodies, then a laboring moon doing work would have fallen to earth eons ago. Isaac Newton's laws of motion cannot work with pull gravity, but they do with Einstein's gravity as a property of the universe, which produces a continuous infusion of energy. In other words, the moon-Earth system becomes the first observable vacuum gravity energy machine. In other words the dynamics of what appears to be a closed system has been producing energy that continues raising the tides into perpetuity along with the force needed for the moon to escape the Earth's gravitational pull 4cm per year. All this is in defiance of Newton's first law which says ``If no force is added to a body it cannot accelerate.'' In this theory, a flowing space-time curves with three dimensions of force. A (flowing) spatial fabric bends around mass and displaces the inverse square field vanishing point property of matter with the appearance of a push-force square of the distance. In other words, the immeasurable universal gravity field appears as measurable local gravitation, concentrating universal gravitational pressure with the square of the distance from the very point was supposed to have disappeared. Needless to say such ``gravity'' necessitates a different beginning.

Hazardous waste management at the local level; The Anchorage, Alaska experience

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wigglesworth, D.

1989-07-01

The need to manage hazardous wastes in the municipality of Anchorage, Alaska, has become increasingly evident in recent years. A task force, representing a broad cross-section of the community, was appointed by the mayor to develop a waste management plan that would address community concerns. Between 1984 and 1986, the Anchorage Hazardous Waste Task Force, supported by municipal staff, local consultants and volunteers from the community developed a plan emphasizing local responsibility and pollution prevention, using management capabilities and technical assistance. This paper describes the development of a non-regulatory hazardous waste management program in Anchorage, Alaska. Plan elements, program fundingmore » and the key role of the local Hazardous Waste Task Force are discussed.« less

Non-contact quantification of laser micro-impulse in water by atomic force microscopy and its application for biomechanics

NASA Astrophysics Data System (ADS)

Hosokawa, Yoichiroh

2011-12-01

We developed a local force measurement system of a femtosecond laser-induced impulsive force, which is due to shock and stress waves generated by focusing an intense femtosecond laser into water with a highly numerical aperture objective lens. In this system, the force localized in micron-sized region was detected by bending movement of a cantilever of atomic force microscope (AFM). Here we calculated the bending movement of the AFM cantilever when the femtosecond laser is focused in water at the vicinity of the cantilever and the impulsive force is loaded on the cantilever. From the result, a method to estimate the total of the impulsive force at the laser focal point was suggested and applied to estimate intercellular adhesion strength.

Control of defect localization in crystalline wrinkling by curvature and topology

NASA Astrophysics Data System (ADS)

Lopez Jimenez, Francisco

We investigate the influence of curvature and topology on crystalline wrinkling patterns in generic elastic bilayers. Our numerical analysis predicts that the total number of defects created by adiabatic compression exhibits universal quadratic scaling for spherical, ellipsoidal and toroidal surfaces over a wide range of system sizes. However, both the localization of individual defects and the orientation of defect chains depend strongly on the local Gaussian curvature and its gradients across a surface. Our results imply that curvature and topology can be utilized to pattern defects in elastic materials, thus promising improved control over hierarchical bending, buckling or folding processes. Generally, this study suggests that bilayer systems provide an inexpensive yet valuable experimental test-bed for exploring the effects of geometrically induced forces on assemblies of topological charges. Joint work with Norbert Stoop, Romain Lagrange, Jorn Dunkel and Pedro M. Reis.

Nonlinear Modeling by Assembling Piecewise Linear Models

NASA Technical Reports Server (NTRS)

Yao, Weigang; Liou, Meng-Sing

2013-01-01

To preserve nonlinearity of a full order system over a parameters range of interest, we propose a simple modeling approach by assembling a set of piecewise local solutions, including the first-order Taylor series terms expanded about some sampling states. The work by Rewienski and White inspired our use of piecewise linear local solutions. The assembly of these local approximations is accomplished by assigning nonlinear weights, through radial basis functions in this study. The efficacy of the proposed procedure is validated for a two-dimensional airfoil moving at different Mach numbers and pitching motions, under which the flow exhibits prominent nonlinear behaviors. All results confirm that our nonlinear model is accurate and stable for predicting not only aerodynamic forces but also detailed flowfields. Moreover, the model is robustness-accurate for inputs considerably different from the base trajectory in form and magnitude. This modeling preserves nonlinearity of the problems considered in a rather simple and accurate manner.

Graphene in ohmic contact for both n-GaN and p-GaN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhong, Haijian; Liu, Zhenghui; Shi, Lin

The wrinkles of single layer graphene contacted with either n-GaN or p-GaN were found both forming ohmic contacts investigated by conductive atomic force microscopy. The local I–V results show that some of the graphene wrinkles act as high-conductive channels and exhibiting ohmic behaviors compared with the flat regions with Schottky characteristics. We have studied the effects of the graphene wrinkles using density-functional-theory calculations. It is found that the standing and folded wrinkles with zigzag or armchair directions have a tendency to decrease or increase the local work function, respectively, pushing the local Fermi level towards n- or p-type GaN andmore » thus improving the transport properties. These results can benefit recent topical researches and applications for graphene as electrode material integrated in various semiconductor devices.« less

The impact of Chernobyl on health and labour market performance.

PubMed

Lehmann, Hartmut; Wadsworth, Jonathan

2011-09-01

Using longitudinal data from Ukraine we examine the extent of any long-lasting effects of exposure to the Chernobyl disaster on the health and labour market performance of the adult workforce. Variation in the local area level of radiation fallout from the Chernobyl accident is considered as a random exogenous shock with which to try to establish its causal impact on poor health, labour force participation, hours worked and wages. There appears to be a significant positive association between local area-level radiation dosage and perception of poor health, though much weaker associations between local area-level dosage and other specific self-reported health conditions. There is also some evidence to suggest that those who lived in areas more exposed to Chernobyl-induced radiation have significantly lower levels of labour market performance 20 years on. Copyright © 2011 Elsevier B.V. All rights reserved.

High-velocity deformation of Al 0.3CoCrFeNi high-entropy alloy: Remarkable resistance to shear failure

DOE PAGES

Li, Z.; Zhao, S.; Diao, H.; ...

2017-02-17

Here, the mechanical behavior of a single phase (fcc) Al 0.3CoCrFeNi high-entropy alloy (HEA) was studied in the low and high strain-rate regimes. The combination of multiple strengthening mechanisms such as solid solution hardening, forest dislocation hardening, as well as mechanical twinning leads to a high work hardening rate, which is significantly larger than that for Al and is retained in the dynamic regime. The resistance to shear localization was studied by dynamically-loading hat-shaped specimens to induce forced shear localization. However, no adiabatic shear band could be observed. It is therefore proposed that the excellent strain hardening ability gives risemore » to remarkable resistance to shear localization, which makes this material an excellent candidate for penetration protection applications such as armors.« less

Magnetoelectric force microscopy based on magnetic force microscopy with modulated electric field.

PubMed

Geng, Yanan; Wu, Weida

2014-05-01

We present the realization of a mesoscopic imaging technique, namely, the Magnetoelectric Force Microscopy (MeFM), for visualization of local magnetoelectric effect. The basic principle of MeFM is the lock-in detection of local magnetoelectric response, i.e., the electric field-induced magnetization, using magnetic force microscopy. We demonstrate MeFM capability by visualizing magnetoelectric domains on single crystals of multiferroic hexagonal manganites. Results of several control experiments exclude artifacts or extrinsic origins of the MeFM signal. The parameters are tuned to optimize the signal to noise ratio.

Shear properties evaluation of a truss core of sandwich beams

NASA Astrophysics Data System (ADS)

Wesolowski, M.; Ludewicz, J.; Domski, J.; Zakrzewski, M.

2017-10-01

The open-cell cores of sandwich structures are locally bonded to the face layers by means of adhesive resin. The sandwich structures composed of different parent materials such as carbon fibre composites (laminated face layers) and metallic core (aluminium truss core) brings the need to closely analyse their adhesive connections which strength is dominated by the shear stress. The presented work considers sandwich beams subjected to the static tests in the 3-point bending with the purpose of estimation of shear properties of the truss core. The main concern is dedicated to the out-of plane shear modulus and ultimate shear stress of the aluminium truss core. The loading of the beam is provided by a static machine. For the all beams the force - deflection history is extracted by means of non-contact optical deflection measurement using PONTOS system. The mode of failure is identified for each beam with the corresponding applied force. A flexural rigidity of the sandwich beams is also discussed based on force - displacement plots.

Characterization of Dielectric Nanocomposites with Electrostatic Force Microscopy

PubMed Central

El Khoury, D.; Fedorenko, V.; Castellon, J.; Laurentie, J.-C.; Fréchette, M.; Ramonda, M.

2017-01-01

Nanocomposites physical properties unexplainable by general mixture laws are usually supposed to be related to interphases, highly present at the nanoscale. The intrinsic dielectric constant of the interphase and its volume need to be considered in the prediction of the effective permittivity of nanodielectrics, for example. The electrostatic force microscope (EFM) constitutes a promising technique to probe interphases locally. This work reports theoretical finite-elements simulations and experimental measurements to interpret EFM signals in front of nanocomposites with the aim of detecting and characterizing interphases. According to simulations, we designed and synthesized appropriate samples to verify experimentally the ability of EFM to characterize a nanoshell covering nanoparticles, for different shell thicknesses. This type of samples constitutes a simplified electrostatic model of a nanodielectric. Experiments were conducted using either DC or AC-EFM polarization, with force gradient detection method. A comparison between our numerical model and experimental results was performed in order to validate our predictions for general EFM-interphase interactions. PMID:29109811

75 FR 29322 - Base Closure and Realignment

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-25

...-6020. Local Redevelopment Authority (LRA) Arizona Installation Name: Air Force Research Laboratory. LRA... provides a corresponding listing of the Local Redevelopment Authorities (LRA) for the Air Force Research Laboratory, Arizona, and portions of the Newport Naval Complex, Rhode Island, recognized by the Secretary of...

The Language Situation in Macao

ERIC Educational Resources Information Center

Yan, Xi

2017-01-01

In postcolonial societies, forces associated with globalization operate along with local geopolitical changes. The complex and multifaceted interactions between local, national, and global forces may take different sociolinguistic shapes in postcolonial societies. This study provides an overview of the language situation in Macao. The Portuguese…

A mitotic SKAP isoform regulates spindle positioning at astral microtubule plus ends

PubMed Central

Kern, David M.; Nicholls, Peter K.; Page, David C.

2016-01-01

The Astrin/SKAP complex plays important roles in mitotic chromosome alignment and centrosome integrity, but previous work found conflicting results for SKAP function. Here, we demonstrate that SKAP is expressed as two distinct isoforms in mammals: a longer, testis-specific isoform that was used for the previous studies in mitotic cells and a novel, shorter mitotic isoform. Unlike the long isoform, short SKAP rescues SKAP depletion in mitosis and displays robust microtubule plus-end tracking, including localization to astral microtubules. Eliminating SKAP microtubule binding results in severe chromosome segregation defects. In contrast, SKAP mutants specifically defective for plus-end tracking facilitate proper chromosome segregation but display spindle positioning defects. Cells lacking SKAP plus-end tracking have reduced Clasp1 localization at microtubule plus ends and display increased lateral microtubule contacts with the cell cortex, which we propose results in unbalanced dynein-dependent cortical pulling forces. Our work reveals an unappreciated role for the Astrin/SKAP complex as an astral microtubule mediator of mitotic spindle positioning. PMID:27138257

The New Work Force. Trends and Issues Alerts.

ERIC Educational Resources Information Center

Imel, Susan

During the last years of this century, the work force will grow more slowly, becoming older, more female, and more disadvantaged. An increasing number of minority groups and immigrants will enter the work force. Despite public demands for reform, education lags behind in preparing youth for employment. The changing work force has many implications…

Rise and fall of competitiveness in individualistic and collectivistic societies.

PubMed

Leibbrandt, Andreas; Gneezy, Uri; List, John A

2013-06-04

Competitiveness pervades life: plants compete for sunlight and water, animals for territory and food, and humans for mates and income. Herein we investigate human competitiveness with a natural experiment and a set of behavioral experiments. We compare competitiveness in traditional fishing societies where local natural forces determine whether fishermen work in isolation or in collectives. We find sharp evidence that fishermen from individualistic societies are far more competitive than fishermen from collectivistic societies, and that this difference emerges with work experience. These findings suggest that humans can evolve traits to specific needs, support the idea that socio-ecological factors play a decisive role for individual competitiveness, and provide evidence how individualistic and collectivistic societies shape economic behavior.

Modulation of local field potential power of the subthalamic nucleus during isometric force generation in patients with Parkinson's disease.

PubMed

Florin, E; Dafsari, H S; Reck, C; Barbe, M T; Pauls, K A M; Maarouf, M; Sturm, V; Fink, G R; Timmermann, L

2013-06-14

Investigations of local field potentials of the subthalamic nucleus of patients with Parkinson's disease have provided evidence for pathologically exaggerated oscillatory beta-band activity (13-30 Hz) which is amenable to physiological modulation by, e.g., voluntary movement. Previous functional magnetic resonance imaging studies in healthy controls have provided evidence for an increase of subthalamic nucleus blood-oxygenation-level-dependant signal in incremental force generation tasks. However, the modulation of neuronal activity by force generation and its relationship to peripheral feedback remain to be elucidated. We hypothesised that beta-band activity in the subthalamic nucleus is modulated by incremental force generation. Subthalamic nucleus local field potentials were recorded intraoperatively in 13 patients with Parkinson's disease (37 recording sites) during rest and five incremental isometric force generation conditions of the arm with applied loads of 0-400 g (in 100-g increments). Repeated measures analysis of variance (ANOVA) revealed a modulation of local field potential (LFP) power in the upper beta-band (in 24-30 Hz; F(₃.₀₄₂)=4.693, p=0.036) and the gamma-band (in 70-76 Hz; F(₄)=4.116, p=0.036). Granger-causality was computed with the squared partial directed coherence and showed no significant modulation during incremental isometric force generation. Our findings indicate that the upper beta- and gamma-band power of subthalamic nucleus local field potentials are modulated by the physiological task of force generation in patients with Parkinson's disease. This modulation seems to be not an effect of a modulation of peripheral feedback. Copyright © 2013 IBRO. Published by Elsevier Ltd. All rights reserved.

Open-ocean boundary conditions from interior data: Local and remote forcing of Massachusetts Bay

USGS Publications Warehouse

Bogden, P.S.; Malanotte-Rizzoli, P.; Signell, R.

1996-01-01

Massachusetts and Cape Cod Bays form a semienclosed coastal basin that opens onto the much larger Gulf of Maine. Subtidal circulation in the bay is driven by local winds and remotely driven flows from the gulf. The local-wind forced flow is estimated with a regional shallow water model driven by wind measurements. The model uses a gravity wave radiation condition along the open-ocean boundary. Results compare reasonably well with observed currents near the coast. In some offshore regions however, modeled flows are an order of magnitude less energetic than the data. Strong flows are observed even during periods of weak local wind forcing. Poor model-data comparisons are attributable, at least in part, to open-ocean boundary conditions that neglect the effects of remote forcing. Velocity measurements from within Massachusetts Bay are used to estimate the remotely forced component of the flow. The data are combined with shallow water dynamics in an inverse-model formulation that follows the theory of Bennett and McIntosh [1982], who considered tides. We extend their analysis to consider the subtidal response to transient forcing. The inverse model adjusts the a priori open-ocean boundary condition, thereby minimizing a combined measure of model-data misfit and boundary condition adjustment. A "consistency criterion" determines the optimal trade-off between the two. The criterion is based on a measure of plausibility for the inverse solution. The "consistent" inverse solution reproduces 56% of the average squared variation in the data. The local-wind-driven flow alone accounts for half of the model skill. The other half is attributable to remotely forced flows from the Gulf of Maine. The unexplained 44% comes from measurement errors and model errors that are not accounted for in the analysis. 

A study approach on ferroelectric domains in BaTiO{sub 3}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rocha, L.S.R.; Cavalcanti, C.S.

Atomic Force Acoustic Microscopy (AFAM) and Piezoresponse Force Microscopy (PFM) were used to study local elastic and electromechanical response in BaTiO{sub 3} ceramics. A commercial multi-mode Scanning Probe Microscopy (SPM) and AFAM mode to image contact stiffness were employed to accomplish the aforementioned purposes. Stiffness parameters along with Young's moduli and piezo coefficients were quantitatively determined. PFM studies were based on electrostatic and electromechanical response from localized tip-surface contact. Comparison was made regarding the Young's moduli obtained by AFAM and PFM. In addition, phase and amplitude images were analyzed based on poling behavior, obtained via the application of − 10more » V to + 10 V local voltage. - Highlights: •Nanoscale behavior of piezo domains in BaTiO{sub 3} ferroelectric materials •Use of Atomic Force Acoustic Microscopy (AFAM) and Piezo Force Microscopy (PFM) •Local elastic and electromechanical response in BaTiO{sub 3} ceramics •The young's moduli obtained from AFAM and PFM.« less

Local vibrational modes of the water dimer - Comparison of theory and experiment

NASA Astrophysics Data System (ADS)

Kalescky, R.; Zou, W.; Kraka, E.; Cremer, D.

2012-12-01

Local and normal vibrational modes of the water dimer are calculated at the CCSD(T)/CBS level of theory. The local H-bond stretching frequency is 528 cm-1 compared to a normal mode stretching frequency of just 143 cm-1. The adiabatic connection scheme between local and normal vibrational modes reveals that the lowering is due to mass coupling, a change in the anharmonicity, and coupling with the local HOH bending modes. The local mode stretching force constant is related to the strength of the H-bond whereas the normal mode stretching force constant and frequency lead to an erroneous underestimation of the H-bond strength.

PREFACE: NC-AFM 2003: Proceedings of the 6th International Conference on Non-contact Atomic Force Microscopy

NASA Astrophysics Data System (ADS)

Reichling, Michael

2004-02-01

Direct nanoscale and atomic resolution imaging is a key issue in nanoscience and nanotechnology. The invention of the dynamic force microscope in the early 1990s was an important step forward in this direction as this instrument provides a universal tool for measuring the topography and many other physical and chemical properties of surfaces at the nanoscale. Operation in the so-called non-contact mode now allows direct atomic resolution imaging of electrically insulating surfaces and nanostructures which has been an unsolved problem during the first decade of nanotechnology. Today, we face a most rapid development of the technique and an extension of its capabilities far beyond imaging; atomically resolved force spectroscopy provides information about local binding properties and researchers now develop sophisticated schemes of force controlled atomic manipulation with the tip of the force microscope. Progress in the field of non-contact force microscopy is discussed at the annually held NC-AFM conferences that are part of a series started in 1998 with a meeting in Osaka, Japan. The 6th International Conference on Non-contact Atomic Force Microscopy took place in Dingle, Ireland, from 31 August to 3 September 2003 and this special issue is a compilation of the original publications of work presented at this meeting. The papers published here well reflect recent achievements, current trends and some of the challenging new directions in non-contact force microscopy that have been discussed during the most stimulating conference days in Dingle. Fundamental aspects of forces and dissipation relevant in imaging and spectroscopy have been covered by experimental and theoretical contributions yielding a more detailed understanding of tip--surface interaction in force microscopy. Novel and improved imaging and spectroscopy techniques have been introduced that either improve the performance of force microscopy or pave the way towards new functionalities and applications. With regard to studies on the specific systems investigated, there was a strong emphasis on oxides and ionics, as well as on organic systems. Following previous pioneering work in uncovering the atomic structure of insulating oxides with force microscopy, it was shown in the meeting that this important class of materials is now accessible for a quantitative atomic scale surface characterization. Single organic molecules and ordered organic layers are building blocks for functional nanostructures currently developed in many laboratories for applications in molecular electronics and sensor technologies. The Dingle conference impressively demonstrated that dynamic force microscopy is ready for its application as an analytical tool for these promising future nanotechnologies. The meeting was a great success scientifically and participants enjoyed the beauty of the conference site. I would like to thank all members of the international steering committee, the programme committee and the co-chairs, J Pethica, A Shluger and G Thornton, for their efforts in preparing the meeting. The members of the local organising committee, J Ballentine-Armstrong, G Cross, S Dunne, S Jarvis and Ö Özer, kept the meeting running smoothly and created a very pleasant atmosphere. The generous financial support from Science Foundation Ireland (SFI), is greatly appreciated; SFI is dramatically raising the profile of Irish science. I would also like to express my sincere gratitude to N Couzin and the journal team from Institute of Physics Publishing for their editorial management and perfect co-operation in the preparation of this special issue.

48 CFR 252.223-7004 - Drug-free work force.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Drug-free work force. 252... Provisions And Clauses 252.223-7004 Drug-free work force. As prescribed in 223.570-2, use the following clause: Drug-Free Work Force (SEP 1988) (a) Definitions. (1) Employee in a sensitive position, as used in...

48 CFR 252.223-7004 - Drug-free work force.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Drug-free work force. 252... Provisions And Clauses 252.223-7004 Drug-free work force. As prescribed in 223.570-2, use the following clause: Drug-Free Work Force (SEP 1988) (a) Definitions. (1) Employee in a sensitive position, as used in...

48 CFR 252.223-7004 - Drug-free work force.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Drug-free work force. 252... Provisions And Clauses 252.223-7004 Drug-free work force. As prescribed in 223.570-2, use the following clause: Drug-Free Work Force (SEP 1988) (a) Definitions. (1) Employee in a sensitive position, as used in...

48 CFR 252.223-7004 - Drug-free work force.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Drug-free work force. 252... Provisions And Clauses 252.223-7004 Drug-free work force. As prescribed in 223.570-2, use the following clause: Drug-Free Work Force (SEP 1988) (a) Definitions. (1) Employee in a sensitive position, as used in...

48 CFR 252.223-7004 - Drug-free work force.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Drug-free work force. 252... Provisions And Clauses 252.223-7004 Drug-free work force. As prescribed in 223.570-2, use the following clause: Drug-Free Work Force (SEP 1988) (a) Definitions. (1) Employee in a sensitive position, as used in...

40 CFR 35.936-14 - Force account work.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Force account work. 35.936-14 Section... Force account work. (a) A grantee must secure the project officer's prior written approval for use of the force account method for (1) any step 1 or step 2 work in excess of $10,000; (2) any sewer...

Fertility and work-force participation: The experience of Melbourne Wives.

PubMed

Ware, H

1976-11-01

Summary Current and retrospective data on the fertility control, work-force participation intentions and practice of Melbourne wives are combined in an examination of the causal link between work-force participation and reduced family size. Stress is laid on the analysis of the interaction between work-force participation and fertility over time, taking into account the proportion of married life spent in the work-force, rather than relying exclusively on a measure of current participation, the only option available in the analysis of census-type data. The wide range of information available makes it possible to study the effects of work-force participation on wives of unimpaired fertility, as well as the different consequences of planned and unplanned participation, and of working in a variety of occupations and for a number of distinct reasons. Examination of the future fertility intentions and current contraceptive practice of the younger wives shows that working wives are not, in these respects, markedly different from their house-wife peers. Overall, the balance of the evidence indicates that in the majority of cases fertility influences work-force participation rather than the converse.

The polarized Debye sheath effect on Kadomtsev-Petviashvili electrostatic structures in strongly coupled dusty plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shahmansouri, M.; Alinejad, H.

2015-04-15

We give a theoretical investigation on the dynamics of nonlinear electrostatic waves in a strongly coupled dusty plasma with strong electrostatic interaction between dust grains in the presence of the polarization force (i.e., the force due to the polarized Debye sheath). Adopting a reductive perturbation method, we derived a three-dimensional Kadomtsev-Petviashvili equation that describes the evolution of weakly nonlinear electrostatic localized waves. The energy integral equation is used to study the existence domains of the localized structures. The analysis provides the localized structure existence region, in terms of the effects of strong interaction between the dust particles and polarization force.

Cellular Contraction and Polarization Drive Collective Cellular Motion.

PubMed

Notbohm, Jacob; Banerjee, Shiladitya; Utuje, Kazage J C; Gweon, Bomi; Jang, Hwanseok; Park, Yongdoo; Shin, Jennifer; Butler, James P; Fredberg, Jeffrey J; Marchetti, M Cristina

2016-06-21

Coordinated motions of close-packed multicellular systems typically generate cooperative packs, swirls, and clusters. These cooperative motions are driven by active cellular forces, but the physical nature of these forces and how they generate collective cellular motion remain poorly understood. Here, we study forces and motions in a confined epithelial monolayer and make two experimental observations: 1) the direction of local cellular motion deviates systematically from the direction of the local traction exerted by each cell upon its substrate; and 2) oscillating waves of cellular motion arise spontaneously. Based on these observations, we propose a theory that connects forces and motions using two internal state variables, one of which generates an effective cellular polarization, and the other, through contractile forces, an effective cellular inertia. In agreement with theoretical predictions, drugs that inhibit contractility reduce both the cellular effective elastic modulus and the frequency of oscillations. Together, theory and experiment provide evidence suggesting that collective cellular motion is driven by at least two internal variables that serve to sustain waves and to polarize local cellular traction in a direction that deviates systematically from local cellular velocity. Copyright © 2016 Biophysical Society. Published by Elsevier Inc. All rights reserved.

Non-radiative processes dominate land surface signals in the climate system

NASA Astrophysics Data System (ADS)

Bright, R. M.; Davin, E.; O'Halloran, T. L.; Pongratz, J.; Zhao, K.; Cescatti, A.

2016-12-01

Perturbations to the surface energy budget linked to land cover/land management changes (LCMC) are rarely included in land-climate assessments although they have long been recognized as important drivers of local climate change. At local scales, climate forcings from LCMC depend strongly on changes to surface energy redistribution by various non-radiative mechanisms, dampening or even outweighing the local radiative effect of an albedo change. The extent to which these mechanisms are locally relevant for different types of LCMC across the world remains largely unquantified. Here, we combine extensive records of remote sensing and in-situ observations to quantify local forcings for nine common real-world LCMC perturbations, identifying their underlying physical mechanisms and analyzing their spatial patterns at the global scale. We find that throughout the densely populated regions, non-radiative forcings dominate the local surface temperature response in 8 of 9 LCMC scenarios. Further, the observed local response to re-/afforestation is an annual cooling in all regions south of the upper conterminous United States, Western Europe, and Indo-China. Given that the global response to re-/afforestation in these regions is likely a cooling, projects here can be seen as attractive mitigation measures. Our results - gridded to a 1° x 1° resolution - can be directly used to evaluate climate models or compute indicators providing a more comprehensive picture of the trade-offs between local and global climate forcings linked to land sector projects and policies.

Estimation of Local Bone Loads for the Volume of Interest.

PubMed

Kim, Jung Jin; Kim, Youkyung; Jang, In Gwun

2016-07-01

Computational bone remodeling simulations have recently received significant attention with the aid of state-of-the-art high-resolution imaging modalities. They have been performed using localized finite element (FE) models rather than full FE models due to the excessive computational costs of full FE models. However, these localized bone remodeling simulations remain to be investigated in more depth. In particular, applying simplified loading conditions (e.g., uniform and unidirectional loads) to localized FE models have a severe limitation in a reliable subject-specific assessment. In order to effectively determine the physiological local bone loads for the volume of interest (VOI), this paper proposes a novel method of estimating the local loads when the global musculoskeletal loads are given. The proposed method is verified for the three VOI in a proximal femur in terms of force equilibrium, displacement field, and strain energy density (SED) distribution. The effect of the global load deviation on the local load estimation is also investigated by perturbing a hip joint contact force (HCF) in the femoral head. Deviation in force magnitude exhibits the greatest absolute changes in a SED distribution due to its own greatest deviation, whereas angular deviation perpendicular to a HCF provides the greatest relative change. With further in vivo force measurements and high-resolution clinical imaging modalities, the proposed method will contribute to the development of reliable patient-specific localized FE models, which can provide enhanced computational efficiency for iterative computing processes such as bone remodeling simulations.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lynch, Kevin; Popp, James

This DOE grant award for was for the period June 1, 2013 to March 31, 2016. Popp was awarded an internship in the Visiting Faculty Program at FNAL in summer of 2015; consequently the unused portion of summer salary funds allowed us to apply for a no-cost extension with our remaining funds until March 31, 2017. That support furnished us with the means to carry out numerous successful projects for Mu2e for nearly four years. Up to now, the driving force to our work has been dictated primarily by the Mu2e Project cost and schedule needs. Our work has beenmore » under the purview of three of the Working Groups to which we belong: Target Station, Electron Tracker, and Stopping Target Monitor. We have carried out a mix of bench-top testing tasks locally, more elaborate work at Fermilab every summer, and extensive software development and simulation studies.« less

Toward an Integrative Computational Model of the Guinea Pig Cardiac Myocyte

PubMed Central

Gauthier, Laura Doyle; Greenstein, Joseph L.; Winslow, Raimond L.

2012-01-01

The local control theory of excitation-contraction (EC) coupling asserts that regulation of calcium (Ca2+) release occurs at the nanodomain level, where openings of single L-type Ca2+ channels (LCCs) trigger openings of small clusters of ryanodine receptors (RyRs) co-localized within the dyad. A consequence of local control is that the whole-cell Ca2+ transient is a smooth continuous function of influx of Ca2+ through LCCs. While this so-called graded release property has been known for some time, its functional importance to the integrated behavior of the cardiac ventricular myocyte has not been fully appreciated. We previously formulated a biophysically based model, in which LCCs and RyRs interact via a coarse-grained representation of the dyadic space. The model captures key features of local control using a low-dimensional system of ordinary differential equations. Voltage-dependent gain and graded Ca2+ release are emergent properties of this model by virtue of the fact that model formulation is closely based on the sub-cellular basis of local control. In this current work, we have incorporated this graded release model into a prior model of guinea pig ventricular myocyte electrophysiology, metabolism, and isometric force production. The resulting integrative model predicts the experimentally observed causal relationship between action potential (AP) shape and timing of Ca2+ and force transients, a relationship that is not explained by models lacking the graded release property. Model results suggest that even relatively subtle changes in AP morphology that may result, for example, from remodeling of membrane transporter expression in disease or spatial variation in cell properties, may have major impact on the temporal waveform of Ca2+ transients, thus influencing tissue level electromechanical function. PMID:22783206

Toward an integrative computational model of the Guinea pig cardiac myocyte.

PubMed

Gauthier, Laura Doyle; Greenstein, Joseph L; Winslow, Raimond L

2012-01-01

The local control theory of excitation-contraction (EC) coupling asserts that regulation of calcium (Ca(2+)) release occurs at the nanodomain level, where openings of single L-type Ca(2+) channels (LCCs) trigger openings of small clusters of ryanodine receptors (RyRs) co-localized within the dyad. A consequence of local control is that the whole-cell Ca(2+) transient is a smooth continuous function of influx of Ca(2+) through LCCs. While this so-called graded release property has been known for some time, its functional importance to the integrated behavior of the cardiac ventricular myocyte has not been fully appreciated. We previously formulated a biophysically based model, in which LCCs and RyRs interact via a coarse-grained representation of the dyadic space. The model captures key features of local control using a low-dimensional system of ordinary differential equations. Voltage-dependent gain and graded Ca(2+) release are emergent properties of this model by virtue of the fact that model formulation is closely based on the sub-cellular basis of local control. In this current work, we have incorporated this graded release model into a prior model of guinea pig ventricular myocyte electrophysiology, metabolism, and isometric force production. The resulting integrative model predicts the experimentally observed causal relationship between action potential (AP) shape and timing of Ca(2+) and force transients, a relationship that is not explained by models lacking the graded release property. Model results suggest that even relatively subtle changes in AP morphology that may result, for example, from remodeling of membrane transporter expression in disease or spatial variation in cell properties, may have major impact on the temporal waveform of Ca(2+) transients, thus influencing tissue level electromechanical function.

Shear localization and effective wall friction in a wall bounded granular flow

NASA Astrophysics Data System (ADS)

Artoni, Riccardo; Richard, Patrick

2017-06-01

In this work, granular flow rheology is investigated by means of discrete numerical simulations of a torsional, cylindrical shear cell. Firstly, we focus on azimuthal velocity profiles and study the effect of (i) the confining pressure, (ii) the particle-wall friction coefficient, (iii) the rotating velocity of the bottom wall and (iv) the cell diameter. For small cell diameters, azimuthal velocity profiles are nearly auto-similar, i.e. they are almost linear with the radial coordinate. Different strain localization regimes are observed : shear can be localized at the bottom, at the top of the shear cell, or it can be even quite distributed. This behavior originates from the competition between dissipation at the sidewalls and dissipation in the bulk of the system. Then we study the effective friction at the cylindrical wall, and point out the strong link between wall friction, slip and fluctuations of forces and velocities. Even if the system is globally below the sliding threshold, force fluctuations trigger slip events, leading to a nonzero wall slip velocity and an effective wall friction coefficient different from the particle-wall one. A scaling law was found linking slip velocity, granular temperature in the main flow direction and effective friction. Our results suggest that fluctuations are an important ingredient for theories aiming to capture the interface rheology of granular materials.

First order reversal curve study of the dipolar interaction in Ni three-dimensional antidot arrays

NASA Astrophysics Data System (ADS)

Li, Bingqing; Chai, Xuzhao; Moeendarbari, Sina; Hao, Yaowu; Gilbert, Dustin A.; Liu, Kai; Zhang, Di; Feng, Gang; Han, Ping; Cheng, X. M.

2014-03-01

Three-dimensional antidot arrays (3DAAs) have attracted considerable attention due to potential applications in sensors, energy storage and transducers. Magnetic 3DAAs also provide an ideal system for studying the effect of dimensionality and morphology on magnetic properties. We report study of dipolar interactions in Ni 3DAAs using the first-order reversal curve (FORC) method. Ordered Ni 3DAAs were fabricated by electrochemical deposition into colloidal crystal templates of self-assembled polystyrene spheres. The samples have the same pore size of about 500 nm but different thicknesses, ranging from 0.3 μm to 1.2 μm, confirmed by scanning electron microscopy (SEM) and atomic force microscopy (AFM). FORCs of the samples with thicknesses of 0.3 μm, 0.8 μm, and 1.2 μm were measured by a vibrating sample magnetometer. The FORC diagram analysis reveals a demagnetizing magnetic dipolar interaction, and a decrease in the interaction strength with the increasing sample thickness, evidenced by a decrease in the spread of the irreversible peak in the bias distribution, as well as a decrease in the tilting of the FORC distribution from the local coercivity axis. Work at BMC and UCD is supported by NSF DMR-1207085 and DMR-1008791, respectively.

Path planning for mobile robot using the novel repulsive force algorithm

NASA Astrophysics Data System (ADS)

Sun, Siyue; Yin, Guoqiang; Li, Xueping

2018-01-01

A new type of repulsive force algorithm is proposed to solve the problem of local minimum and the target unreachable of the classic Artificial Potential Field (APF) method in this paper. The Gaussian function that is related to the distance between the robot and the target is added to the traditional repulsive force, solving the problem of the goal unreachable with the obstacle nearby; variable coefficient is added to the repulsive force component to resize the repulsive force, which can solve the local minimum problem when the robot, the obstacle and the target point are in the same line. The effectiveness of the algorithm is verified by simulation based on MATLAB and actual mobile robot platform.

Work Force Information and Career-Technical Education. In Brief: Fast Facts for Policy and Practice No. 10.

ERIC Educational Resources Information Center

Sommers, Dixie

To prepare young people and adults for labor market success, career-technical education (CTE) practitioners must know how to find and use work force information. Recent federal legislation, including the Workforce Investment Act of 1998, underscores the importance of work force education. The nationwide work force information system makes data on…

A socioecological analysis of the determinants of national public health nutrition work force capacity: Australia as a case study.

PubMed

Hughes, Roger

2006-01-01

This article uses a socioecological analytical approach to assess the capacity of the public health nutrition work force in Australia as a prelude to work force development strategy planning. It demonstrates how the socioecological model can be used to assess and inform the development of the infrastructure required for effective public health nutrition effort. An interpretive case study method was used involving triangular analysis of quantitative and qualitative data from multiple sources including semistructured interviews with advanced-level practitioners, literature review, a cross-sectional national work force survey, and position description audit and consensus development using a Delphi study. The findings of this analysis indicate that the Australian public health nutrition work force's capacity to effectively address priority nutrition issues is limited by determinants that can be categorized as relating to human resource infrastructure, organizational and policy environments, intelligence access and use, practice improvement and learning systems, and work force preparation. This socioecological analysis supports an intelligence-based focus for work force development effort in Australia and a conceptual framework for work force capacity assessment with potential applications in other countries.

Prediction of forces and moments for hypersonic flight vehicle control effectors

NASA Technical Reports Server (NTRS)

Maughmer, Mark D.; Long, Lyle N.; Guilmette, Neal; Pagano, Peter

1993-01-01

This research project includes three distinct phases. For completeness, all three phases of the work are briefly described in this report. The goal was to develop methods of predicting flight control forces and moments for hypersonic vehicles which could be used in a preliminary design environment. The first phase included a preliminary assessment of subsonic/supersonic panel methods and hypersonic local flow inclination methods for such predictions. While these findings clearly indicated the usefulness of such methods for conceptual design activities, deficiencies exist in some areas. Thus, a second phase of research was conducted in which a better understanding was sought for the reasons behind the successes and failures of the methods considered, particularly for the cases at hypersonic Mach numbers. This second phase involved using computational fluid dynamics methods to examine the flow fields in detail. Through these detailed predictions, the deficiencies in the simple surface inclination methods were determined. In the third phase of this work, an improvement to the surface inclination methods was developed. This used a novel method for including viscous effects by modifying the geometry to include the viscous/shock layer.

Topological photonics: an observation of Landau levels for optical photons

NASA Astrophysics Data System (ADS)

Schine, Nathan; Ryou, Albert; Sommer, Ariel; Simon, Jonathan

We present the first experimental realization of a bulk magnetic field for optical photons. By using a non-planar ring resonator, we induce an image rotation on each round trip through the resonator. This results in a Coriolis/Lorentz force and a centrifugal anticonfining force, the latter of which is cancelled by mirror curvature. Using a digital micromirror device to control both amplitude and phase, we inject arbitrary optical modes into our resonator. Spatial- and energy- resolved spectroscopy tracks photonic eigenstates as residual trapping is reduced, and we observe photonic Landau levels as the eigenstates become degenerate. We show that there is a conical geometry of the resulting manifold for photon dynamics and present a measurement of the local density of states that is consistent with Landau levels on a cone. While our work already demonstrates an integer quantum Hall material composed of photons, we have ensured compatibility with strong photon-photon interactions, which will allow quantum optical studies of entanglement and correlation in manybody systems including fractional quantum Hall fluids. This work was supported by DOE, DARPA, and AFOSR.

Target: Alcohol Abuse in the Hard-to-Reach Work Force. Ideas and Resources for Responding to Problems of the Hard-to-Reach Work Force.

ERIC Educational Resources Information Center

Informatics, Inc., Rockville, MD.

This guide is designed as a source of ideas and information for individuals and organizations interested in occupational alcoholism programs for the hard-to-reach work force. Following a brief overview of the problem and a report on progress in occupational alcoholism programming, a working definition of the hard-to-reach work force is offered;…

Nanotribological effects of hair care products and environment on human hair using atomic force microscopy

NASA Astrophysics Data System (ADS)

Latorre, Carmen; Bhushan, Bharat

2005-07-01

Tribological properties are useful in the study of human hair and other biological materials. Major sources of investigation for conditioner treated hair includes localization of conditioner, mechanisms related to changes in surface roughness, friction, and adhesion on the nanoscale due to conditioner agents, and how the products change the microstructure of the cuticle. The paper presents nanotribological studies investigating surface roughness, friction, and adhesion using atomic force/friction force microscopy (AFM/FFM). Test samples include virgin and chemically damaged hair, both with and without commercial conditioner treatment, as well as chemically damaged hair with experimental conditioner treatments. Friction force mapping provides insight into the localized change in friction caused by the application of hair care materials. Adhesive force maps to study adhesion on the cuticle surface provide information about localization and distribution of conditioner as well. A discussion is presented on these properties of hair as a function of relative humidity, temperature, durability, and conditioning treatments.

Design development scopes towards occupational wellness of women workers: specific reference to local agro based food processing industries in NE India.

PubMed

Bhattacharyya, Nandita; Chakrabarti, Debkumar

2012-01-01

Women workers constitute one of the most vulnerable segments of the country's labour force. They often face different workplace health challenges than men do. They are engaged in a range of work that extends from heavy, monotonous, repetitive jobs, which are in many times experienced with low-paid and involves in long hours of work. Women's workplace health problems are frequently compounded by getting more of the same at home--the "double jeopardy" of domestic work. Specific issues to improve the workers motivation leading to enhancement of productivity and improving occupational health and safety were addressed. Context specific application of ergonomics principles were studied in the process of designing of work related equipment of local fruit processing units, as well as in tea industry, covering 180 subjects selected purposively. Ergonomic risk factors prevailed among the workers associates productivity and relevant health issues were quantified using QEC, RULA. NMQ was used to gather data on prevalence of CTDs among the workers. Pineapple peeling, tea leaves plucking were found highly labour intensive, done manually. Postures scores found were very high. WRMSDs were prevalent among the workers. Scope for ergonomic design intervention was observed to improve productivity and occupational health.

Chemical Industry, the Environment, and Russian Provincial Society: The Case of the Kokshan Chemical Works (1850-1925).

PubMed

Vinogradov, Andrei; Petriashin, Stanislav

2018-05-01

This article explores interactions between the chemical industry, the environment, and Russian provincial society in the late nineteenth and early twentieth centuries, using the example of the Kokshan chemical works, in the Elabuga District, Viatka Province, Russian Empire (today Mendeleevsk District, Republic of Tatarstan, Russian Federation). The plant's location facilitated its rapid development due to a number of factors, including a cheap labour force, the availability of raw materials, and the absence of local competition. However, the factory's development came in conjunction with the deterioration of the environment and subsequent health problems for employees and the surrounding population. Conflicts connected with the Kokshan works illustrate differences between this case and similar examples in Russia and Europe. In Viatka Province, the local community remained mostly silent regarding these issues, and made no demands for improving sanitary control and working conditions or reducing pollution; rather, it was distant activists who personally suffered no harm who intervened in the interest of social justice. The history of the company reflects the contrast between the transfer of European technological innovations to Russia and laborious efforts to increase national wealth on the one hand, and the exploitation of the environment and endangerment of workers' health on the other.

Point prevalence survey for tick-borne pathogens in military working dogs, shelter animals, and pet populations in northern Colombia.

PubMed

McCown, M E; Alleman, A; Sayler, K A; Chandrashekar, R; Thatcher, B; Tyrrell, P; Stillman, B; Beall, M; Barbet, A F

2014-01-01

Based on the high tick-borne pathogen results from a 2011 surveillance study in three Colombian cities, an in-depth point prevalence survey was conducted to determine the seroprevalence of tick-borne pathogens at a specific point in time in 70 working dogs, 101 shelter dogs, and 47 client-owned dogs in Barranquilla, Colombia. Of the 218 serum samples, 163 (74%) were positive for Ehrlichia canis and 116 (53%) for Anaplasma platys. Exposure to tick-borne pathogens was highest in shelter and working dogs where more than 90% of the samples were seropositive or positive on polymerase chain reaction for one or more organisms as compared to 51% in client-owned animals. Surveillance for exposure to tick-borne pathogens provides vital information necessary to protect and conserve the health of local humans and animals, deployed military service members, and working dogs in various parts of the world. This study and resultant data demonstrate the value of following a broad-based surveillance study with a more specific, focused analysis in an area of concern. This area?s high levels of exposure warrant emphasis by medical planners and advisors on precautionary measures for military dogs, Special Operations Forces personnel, and the local public. 2014.

Distribution of joint local and total size and of extension for avalanches in the Brownian force model

NASA Astrophysics Data System (ADS)

Delorme, Mathieu; Le Doussal, Pierre; Wiese, Kay Jörg

2016-05-01

The Brownian force model is a mean-field model for local velocities during avalanches in elastic interfaces of internal space dimension d , driven in a random medium. It is exactly solvable via a nonlinear differential equation. We study avalanches following a kick, i.e., a step in the driving force. We first recall the calculation of the distributions of the global size (total swept area) and of the local jump size for an arbitrary kick amplitude. We extend this calculation to the joint density of local and global sizes within a single avalanche in the limit of an infinitesimal kick. When the interface is driven by a single point, we find new exponents τ0=5 /3 and τ =7 /4 , depending on whether the force or the displacement is imposed. We show that the extension of a "single avalanche" along one internal direction (i.e., the total length in d =1 ) is finite, and we calculate its distribution following either a local or a global kick. In all cases, it exhibits a divergence P (ℓ ) ˜ℓ-3 at small ℓ . Most of our results are tested in a numerical simulation in dimension d =1 .

Energetic costs of producing muscle work and force in a cyclical human bouncing task

PubMed Central

Kuo, Arthur D.

2011-01-01

Muscles expend energy to perform active work during locomotion, but they may also expend significant energy to produce force, for example when tendons perform much of the work passively. The relative contributions of work and force to overall energy expenditure are unknown. We therefore measured the mechanics and energetics of a cyclical bouncing task, designed to control for work and force. We hypothesized that near bouncing resonance, little work would be performed actively by muscle, but the cyclical production of force would cost substantial metabolic energy. Human subjects (n = 9) bounced vertically about the ankles at inversely proportional frequencies (1–4 Hz) and amplitudes (15–4 mm), such that the overall rate of work performed on the body remained approximately constant (0.30 ± 0.06 W/kg), but the forces varied considerably. We used parameter identification to estimate series elasticity of the triceps surae tendon, as well as the work performed actively by muscle and passively by tendon. Net metabolic energy expenditure for bouncing at 1 Hz was 1.15 ± 0.31 W/kg, attributable mainly to active muscle work with an efficiency of 24 ± 3%. But at 3 Hz (near resonance), most of the work was performed passively, so that active muscle work could account for only 40% of the net metabolic rate of 0.76 ± 0.28 W/kg. Near resonance, a cost for cyclical force that increased with both amplitude and frequency of force accounted for at least as much of the total energy expenditure as a cost for work. Series elasticity reduces the need for active work, but energy must still be expended for force production. PMID:21212245

Joining Forces. A Team Approach to Secondary School Development.

ERIC Educational Resources Information Center

Miller, Rima; Corcoran, Thomas B.

This manual is designed to guide the implementation of the Joining Forces Program, a comprehensive improvement process for secondary schools. Implementation of the program requires the cooperative effort of the local school district, state and local education associations, and the administration and staff of participating schools. Joining Forces…

Effect of large deformation and surface stiffening on the transmission of a line load on a neo-Hookean half space.

PubMed

Wu, Haibin; Liu, Zezhou; Jagota, Anand; Hui, Chung-Yuen

2018-03-07

A line force acting on a soft elastic solid, say due to the surface tension of a liquid drop, can cause significant deformation and the formation of a kink close to the point of force application. Analysis based on linearized elasticity theory shows that sufficiently close to its point of application, the force is borne entirely by the surface stress, not by the elasticity of the substrate; this local balance of three forces is called Neumann's triangle. However, it is not difficult to imagine realistic properties for which this force balance cannot be satisfied. For example, if the line force corresponds to surface tension of water, the numerical values of (unstretched) solid-vapor and solid-liquid surface stresses can easily be such that their sum is insufficient to balance the applied force. In such cases conventional (or naïve) Neumann's triangle of surface forces must break down. Here we study how force balance is rescued from the breakdown of naïve Neumann's triangle by a combination of (a) large hyperelastic deformations of the underlying bulk solid, and (b) increase in surface stress due to surface elasticity (surface stiffening). For a surface with constant surface stress (no surface stiffening), we show that the linearized theory remains accurate if the applied force is less than about 1.3 times the solid surface stress. For a surface in which the surface stress increases linearly with the surface stretch, we find that the Neumann's triangle construction works well as long as we replace the constant surface stress in the naïve Neumann triangle by the actual surface stress underneath the line load.

Ionic liquids-mediated interactions between nanorods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yu, Zhou; Zhang, Fei; Huang, Jingsong

Surface forces mediated by room-temperature ionic liquids (RTILs) play an essential role in diverse applications including self-assembly, lubrication, and electrochemical energy storage. In this work, using molecular simulations we study the interactions between two nanorods immersed in model RTILs at rod-rod separations where both structural and double layer forces are important. The interaction force between neutral rods oscillates as the two rods approach each other, similar to the classical structural forces. Such oscillatory force originates from the density oscillation of RTILs near each rod and is affected by the packing constraints imposed by the neighboring rods. The oscillation period andmore » decay length of the oscillatory force are mainly dictated by the ion density distribution near isolated nanorods. When charges are introduced on the rods, the interaction force remains short-range and oscillatory, similar to the interactions between planar walls mediated by some protic RTILs reported earlier. Nevertheless, introducing net charges to the rods greatly changes the rod-rod interactions, e.g., by delaying the appearance of the first force trough and increasing the oscillation period and decay length of the interaction force. The oscillation period and decay length of the oscillatory force and free energy are commensurate with those of the space charge density near an isolated, charged rod. The free energy of rod-rod interactions reaches local minima (maxima) at rod-rod separations when the space charges near the two rods interfere constructively (destructively). Here, the insight on the short-range interactions between nanorods in RTILs helps guide the design of novel materials, e.g., crystalline ion gels based on rigid-rod polyanions and RTILs.« less

Configurational forces in electronic structure calculations using Kohn-Sham density functional theory

NASA Astrophysics Data System (ADS)

Motamarri, Phani; Gavini, Vikram

2018-04-01

We derive the expressions for configurational forces in Kohn-Sham density functional theory, which correspond to the generalized variational force computed as the derivative of the Kohn-Sham energy functional with respect to the position of a material point x . These configurational forces that result from the inner variations of the Kohn-Sham energy functional provide a unified framework to compute atomic forces as well as stress tensor for geometry optimization. Importantly, owing to the variational nature of the formulation, these configurational forces inherently account for the Pulay corrections. The formulation presented in this work treats both pseudopotential and all-electron calculations in a single framework, and employs a local variational real-space formulation of Kohn-Sham density functional theory (DFT) expressed in terms of the nonorthogonal wave functions that is amenable to reduced-order scaling techniques. We demonstrate the accuracy and performance of the proposed configurational force approach on benchmark all-electron and pseudopotential calculations conducted using higher-order finite-element discretization. To this end, we examine the rates of convergence of the finite-element discretization in the computed forces and stresses for various materials systems, and, further, verify the accuracy from finite differencing the energy. Wherever applicable, we also compare the forces and stresses with those obtained from Kohn-Sham DFT calculations employing plane-wave basis (pseudopotential calculations) and Gaussian basis (all-electron calculations). Finally, we verify the accuracy of the forces on large materials systems involving a metallic aluminum nanocluster containing 666 atoms and an alkane chain containing 902 atoms, where the Kohn-Sham electronic ground state is computed using a reduced-order scaling subspace projection technique [P. Motamarri and V. Gavini, Phys. Rev. B 90, 115127 (2014), 10.1103/PhysRevB.90.115127].

Ionic liquids-mediated interactions between nanorods

DOE PAGES

Yu, Zhou; Zhang, Fei; Huang, Jingsong; ...

2017-10-06

Surface forces mediated by room-temperature ionic liquids (RTILs) play an essential role in diverse applications including self-assembly, lubrication, and electrochemical energy storage. In this work, using molecular simulations we study the interactions between two nanorods immersed in model RTILs at rod-rod separations where both structural and double layer forces are important. The interaction force between neutral rods oscillates as the two rods approach each other, similar to the classical structural forces. Such oscillatory force originates from the density oscillation of RTILs near each rod and is affected by the packing constraints imposed by the neighboring rods. The oscillation period andmore » decay length of the oscillatory force are mainly dictated by the ion density distribution near isolated nanorods. When charges are introduced on the rods, the interaction force remains short-range and oscillatory, similar to the interactions between planar walls mediated by some protic RTILs reported earlier. Nevertheless, introducing net charges to the rods greatly changes the rod-rod interactions, e.g., by delaying the appearance of the first force trough and increasing the oscillation period and decay length of the interaction force. The oscillation period and decay length of the oscillatory force and free energy are commensurate with those of the space charge density near an isolated, charged rod. The free energy of rod-rod interactions reaches local minima (maxima) at rod-rod separations when the space charges near the two rods interfere constructively (destructively). Here, the insight on the short-range interactions between nanorods in RTILs helps guide the design of novel materials, e.g., crystalline ion gels based on rigid-rod polyanions and RTILs.« less

Self-consistent perturbed equilibrium with neoclassical toroidal torque in tokamaks

DOE PAGES

Park, Jong-Kyu; Logan, Nikolas C.

2017-03-01

Toroidal torque is one of the most important consequences of non-axisymmetric fields in tokamaks. The well-known neoclassical toroidal viscosity (NTV) is due to the second-order toroidal force from anisotropic pressure tensor in the presence of these asymmetries. This work shows that the first-order toroidal force originating from the same anisotropic pressure tensor, despite having no flux surface average, can significantly modify the local perturbed force balance and thus must be included in perturbed equilibrium self-consistent with NTV. The force operator with an anisotropic pressure tensor is not self-adjoint when the NTV torque is finite and thus is solved directly formore » each component. This approach yields a modified, non-self-adjoint Euler-Lagrange equation that can be solved using a variety of common drift-kinetic models in generalized tokamak geometry. The resulting energy and torque integral provides a unique way to construct a torque response matrix, which contains all the information of self-consistent NTV torque profiles obtainable by applying non-axisymmetric fields to the plasma. This torque response matrix can then be used to systematically optimize non-axisymmetric field distributions for desired NTV profiles. Published by AIP Publishing.« less

Measurement of macrophage adhesion using optical tweezers with backward-scattered detection

NASA Astrophysics Data System (ADS)

Wei, Sung-Yang; Su, Yi-Jr; Shih, Po-Chen; Yang, Shih-Mo; Hsu, Long

2010-08-01

Macrophages are members of the leukocyte family. Tissue damage causes inflammation and release of vasoactive and chemotactic factors, which trigger a local increase in blood flow and capillary permeability. Then, leukocytes accumulate quickly to the infection site. The leukocyte extravasation process takes place according to a sequence of events that involve tethering, activation by a chemoattractant stimulus, adhesion by integrin binding, and migrating to the infection site. The leukocyte extravasation process reveals that adhesion is an important part of the immune system. Optical tweezers have become a useful tool with broad applications in biology and physics. In force measurement, the trapped bead as a probe usually uses a polystyrene bead of 1 μm diameter to measure adhesive force between the trapped beads and cell by optical tweezers. In this paper, using the ray-optics model calculated trapping stiffness and defined the linear displacement ranges. By the theoretical values of stiffness and linear displacement ranges, this study attempted to obtain a proper trapped particle size in measuring adhesive force. Finally, this work investigates real-time adhesion force measurements between human macrophages and trapped beads coated with lipopolysaccharides using optical tweezers with backscattered detection.

Combined Lorentz force and ultrasound Doppler velocimetry in a vertical convection liquid metal flow

NASA Astrophysics Data System (ADS)

Zürner, Till; Vogt, Tobias; Resagk, Christian; Eckert, Sven; Schumacher, Jörg

2017-11-01

We report experimental studies on turbulent vertical convection flow in the liquid metal alloy gallium-indium-tin. Flow measurements were conducted by a combined use of local Lorentz force velocimetry (LLFV) and ultrasound Doppler velocimetry (UDV). It is known that the forced convection flow in a duct generates a force on the LLFV magnet system, that grows proportional to the flow velocity. We show that for the slower flow of natural convection LLFV retains this linear dependence in the range of micronewtons. Furthermore experimental results on the scaling of heat and momentum transport with the thermal driving are presented. The results cover a range of Rayleigh numbers 3 ×105 < Ra < 3 ×107 at a Prandtl number Pr 0.032 . The Nusselt number Nu is found to scale as Nu Ra0.31 . A Reynolds number Rez based on the vertical velocities close the heated and cooled side walls scales with Rez Ra0.45 . Additionally a Reynolds number based on the horizontal flow component is scaling as Rex Ra0.67 . These results agree well with numerical simulations and theoretical predictions. This work is funded by the Deutsche Forschungsgemeinschaft under Grant No. GRK 1567.

Assessing differences in hours worked between male and female dentists: an analysis of cross-sectional national survey data from 1979 through 1999.

PubMed

Walton, Surrey M; Byck, Gayle R; Cooksey, Judith A; Kaste, Linda M

2004-05-01

Women are increasingly entering the dental work force. This study examines the impact of sex, age and other demographic characteristics on dentists' work force participation and on hours worked from 1979 through 1999. The study drew on cross-sectional data on dentists (4,209 men and 354 women) from national population surveys conducted by the U.S. Bureau of Labor Statistics from 1979 through 1999. The authors used descriptive statistics and regression analyses to examine sex differences in work force participation and in hours worked across age, as well as other factors. Work force participation was high for both men and women. Men worked more hours and worked part time less frequently; they worked more than 42 hours per week more frequently. Older dentists worked fewer hours, with a larger impact of age seen among men. Having children had a significantly greater effect on the number of hours worked per week among female dentists than among male dentists. There were significant differences in dentists' hours worked by sex and by age. The consistency of the results with past studies suggests these differences will hold in the near future. Women's entry into the dental work force has been significant and has helped maintain the supply of dentists. Sex differences in the work force should be considered in evaluating the supply of dentists and related work force policy.

Task III: Development of an Effective Computational Methodology for Body Force Representation of High-speed Rotor 37

NASA Technical Reports Server (NTRS)

Tan, Choon-Sooi; Suder, Kenneth (Technical Monitor)

2003-01-01

A framework for an effective computational methodology for characterizing the stability and the impact of distortion in high-speed multi-stage compressor is being developed. The methodology consists of using a few isolated-blade row Navier-Stokes solutions for each blade row to construct a body force database. The purpose of the body force database is to replace each blade row in a multi-stage compressor by a body force distribution to produce same pressure rise and flow turning. To do this, each body force database is generated in such a way that it can respond to the changes in local flow conditions. Once the database is generated, no hrther Navier-Stokes computations are necessary. The process is repeated for every blade row in the multi-stage compressor. The body forces are then embedded as source terms in an Euler solver. The method is developed to have the capability to compute the performance in a flow that has radial as well as circumferential non-uniformity with a length scale larger than a blade pitch; thus it can potentially be used to characterize the stability of a compressor under design. It is these two latter features as well as the accompanying procedure to obtain the body force representation that distinguish the present methodology from the streamline curvature method. The overall computational procedures have been developed. A dimensional analysis was carried out to determine the local flow conditions for parameterizing the magnitudes of the local body force representation of blade rows. An Euler solver was modified to embed the body forces as source terms. The results from the dimensional analysis show that the body forces can be parameterized in terms of the two relative flow angles, the relative Mach number, and the Reynolds number. For flow in a high-speed transonic blade row, they can be parameterized in terms of the local relative Mach number alone.

The Importance of Freshwater to Spatial Variability of Aragonite Saturation State in the Gulf of Alaska

NASA Astrophysics Data System (ADS)

Siedlecki, Samantha A.; Pilcher, Darren J.; Hermann, Albert J.; Coyle, Ken; Mathis, Jeremy

2017-11-01

High-latitude and subpolar regions like the Gulf of Alaska (GOA) are more vulnerable than equatorial regions to rising carbon dioxide (CO2) levels, in part due to local processes that amplify the global signal. Recent field observations have shown that the shelf of the GOA is currently experiencing seasonal corrosive events (carbonate mineral saturation states Ω, Ω < 1), including suppressed Ω in response to ocean acidification as well as local processes like increased low-alkalinity glacial meltwater discharge. While the glacial discharge mainly influences the inner shelf, on the outer shelf, upwelling brings corrosive waters from the deep GOA. In this work, we develop a high-resolution model for carbon dynamics in the GOA, identify regions of high variability of Ω, and test the sensitivity of those regions to changes in the chemistry of glacial meltwater discharge. Results indicate the importance of this climatically sensitive and relatively unconstrained regional freshwater forcing for Ω variability in the nearshore. The increase was nearly linear at 0.002 Ω per 100 µmol/kg increase in alkalinity in the freshwater runoff. We find that the local winds, biological processes, and freshwater forcing all contribute to the spatial distribution of Ω and identify which of these three is highly correlated to the variability in Ω. Given that the timing and magnitude of these processes will likely change during the next few decades, it is critical to elucidate the effect of local processes on the background ocean acidification signal using robust models, such as the one described here.

Nanomechanical characterization of nanostructured bainitic steel: Peak Force Microscopy and Nanoindentation with AFM

PubMed Central

Morales-Rivas, Lucia; González-Orive, Alejandro; Garcia-Mateo, Carlos; Hernández-Creus, Alberto; Caballero, Francisca G.; Vázquez, Luis

2015-01-01

The full understanding of the deformation mechanisms in nanostructured bainite requires the local characterization of its mechanical properties, which are expected to change from one phase, bainitic ferrite, to another, austenite. This study becomes a challenging process due to the bainitic nanostructured nature and high Young’s modulus. In this work, we have carried out such study by means of the combination of AFM-based techniques, such as nanoindentation and Peak Force Quantitative Nanomechanical Mapping (PF-QNM) measurements. We have addressed critically the limits and advantages of these techniques and been able to measure some elastoplastic parameters of both phases. Specifically, we have analyzed by PF-QNM two nanostructured bainitic steels, with a finer and a coarser structure, and found that both phases have a similar Young’s modulus. PMID:26602631

Fibroblasts Lead the Way: A Unified View of 3D Cell Motility.

PubMed

Petrie, Ryan J; Yamada, Kenneth M

2015-11-01

Primary human fibroblasts are remarkably adaptable, able to migrate in differing types of physiological 3D tissue and on rigid 2D tissue culture surfaces. The crawling behavior of these and other vertebrate cells has been studied intensively, which has helped generate the concept of the cell motility cycle as a comprehensive model of 2D cell migration. However, this model fails to explain how cells force their large nuclei through the confines of a 3D matrix environment and why primary fibroblasts can use more than one mechanism to move in 3D. Recent work shows that the intracellular localization of myosin II activity is governed by cell-matrix interactions to both force the nucleus through the extracellular matrix (ECM) and dictate the type of protrusions used to migrate in 3D. Published by Elsevier Ltd.

Unraveling the genetic driving forces enabling antibiotic resistance at the single cell level

NASA Astrophysics Data System (ADS)

Bos, Julia

Bacteria are champions at finding ways to quickly respond and adapt to environments like the human gut, known as the epicentre of antibiotic resistance. How do they do it? Combining molecular biology tools to microfluidic and fluorescence microscopy technologies, we monitor the behavior of bacteria at the single cell level in the presence of non-toxic doses of antibiotics. By tracking the chromosome dynamics of Escherichia coli cells upon antibiotic treatment, we examine the changes in the number, localization and content of the chromosome copies within one cell compartment or between adjacent cells. I will discuss how our work pictures the bacterial genomic plasticity as a driving force in evolution and how it provides access to the mechanisms controlling the subtle balance between genetic diversity and stability in the development of antibiotic resistance.

Joule heating effects on particle immobilization in insulator-based dielectrophoretic devices

PubMed Central

Gallo-Villanueva, Roberto C.; Sano, Michael B.; Lapizco-Encinas, Blanca H.; Davalos, Rafael V.

2014-01-01

In this work, the temperature effects due to Joule heating obtained by application of a DC electric potential were investigated for a microchannel with cylindrical insulating posts employed for insulator based dielectrophoresis (iDEP). The conductivity of the suspending medium, the local electric field, and the gradient of the squared electric field, which directly affect the magnitude of the dielectrophoretic force exerted on particles, were computationally simulated employing COMSOL Multiphysics. It was observed that a temperature gradient is formed along the microchannel which redistributes the conductivity of the suspending medium leading to an increase of the dielectrophoretic force towards the inlet of the channel while decreasing towards the outlet. Experimental results are in good agreement with simulations on the particle trapping zones anticipated. This study demonstrates the importance of considering Joule heating effects when designing iDEP systems. PMID:24002905

NaCl nucleation from brine in seeded simulations: Sources of uncertainty in rate estimates.

PubMed

Zimmermann, Nils E R; Vorselaars, Bart; Espinosa, Jorge R; Quigley, David; Smith, William R; Sanz, Eduardo; Vega, Carlos; Peters, Baron

2018-06-14

This work reexamines seeded simulation results for NaCl nucleation from a supersaturated aqueous solution at 298.15 K and 1 bar pressure. We present a linear regression approach for analyzing seeded simulation data that provides both nucleation rates and uncertainty estimates. Our results show that rates obtained from seeded simulations rely critically on a precise driving force for the model system. The driving force vs. solute concentration curve need not exactly reproduce that of the real system, but it should accurately describe the thermodynamic properties of the model system. We also show that rate estimates depend strongly on the nucleus size metric. We show that the rate estimates systematically increase as more stringent local order parameters are used to count members of a cluster and provide tentative suggestions for appropriate clustering criteria.

Experimental study of vertical stress profiles of a confined granular bed under static and dynamic conditions.

PubMed

Mandato, S; Cuq, B; Ruiz, T

2012-07-01

In a wet agglomeration process inside a low shear mixer, the blade function is to induce i) homogenization of the liquid sprayed on the powder surface and ii) a stress field able to transfer the mechanical energy at the particle scale. In this work we study the mechanical state of a confined powder bed through the analysis of stress distributions (by force measurements) in a rectangular cell in two cases: for a classical model powder (i.e. glass beads) and a complex powder (i.e. wheat semolina). Two types of vertical stress profiles are obtained according to the type of measurements carried out in the powder bed, either locally (at different positions in the cell) or globally (at the entire base). The global vertical stress profile follows Janssen's model and the local vertical stress profile highlights a critical length, identified as the percolation threshold of the force network, and a shielding length near the bottom, which is similar to an influence length of the side walls. In the context of wet agglomeration, the results allow to consider the role of the characteristic lengths in the mixing bowl under vertical mechanical solicitation.

Characterization of the Deep Water Surface Wave Variability in the California Current Region

NASA Astrophysics Data System (ADS)

Villas Bôas, Ana B.; Gille, Sarah T.; Mazloff, Matthew R.; Cornuelle, Bruce D.

2017-11-01

Surface waves are crucial for the dynamics of the upper ocean not only because they mediate exchanges of momentum, heat, energy, and gases between the ocean and the atmosphere, but also because they determine the sea state. The surface wave field in a given region is set by the combination of local and remote forcing. The present work characterizes the seasonal variability of the deep water surface wave field in the California Current region, as retrieved from over two decades of satellite altimetry data combined with wave buoys and wave model hindcast (WaveWatch III). In particular, the extent to which the local wind modulates the variability of the significant wave height, peak period, and peak direction is assessed. During spring/summer, regional-scale wind events of up to 10 m/s are the dominant forcing for waves off the California coast, leading to relatively short-period waves (8-10 s) that come predominantly from the north-northwest. The wave climatology throughout the California Current region shows average significant wave heights exceeding 2 m during most of the year, which may have implications for the planning and retrieval methods of the Surface Water and Ocean Topography (SWOT) satellite mission.

Force transmissibility versus displacement transmissibility

NASA Astrophysics Data System (ADS)

Lage, Y. E.; Neves, M. M.; Maia, N. M. M.; Tcherniak, D.

2014-10-01

It is well-known that when a single-degree-of-freedom (sdof) system is excited by a continuous motion of the foundation, the force transmissibility, relating the force transmitted to the foundation to the applied force, equals the displacement transmissibility. Recent developments in the generalization of the transmissibility to multiple-degree-of-freedom (mdof) systems have shown that similar simple and direct relations between both types of transmissibility do not appear naturally from the definitions, as happens in the sdof case. In this paper, the authors present their studies on the conditions under which it is possible to establish a relation between force transmissibility and displacement transmissibility for mdof systems. As far as the authors are aware, such a relation is not currently found in the literature, which is justified by being based on recent developments in the transmissibility concept for mdof systems. Indeed, it does not appear naturally, but the authors observed that the needed link is present when the displacement transmissibility is obtained between the same coordinates where the applied and reaction forces are considered in the force transmissibility case; this implies that the boundary conditions are not exactly the same and instead follow some rules. This work presents a formal derivation of the explicit relation between the force and displacement transmissibilities for mdof systems, and discusses its potential and limitations. The authors show that it is possible to obtain the displacement transmissibility from measured forces, and the force transmissibility from measured displacements, opening new perspectives, for example, in the identification of applied or transmitted forces. With this novel relation, it becomes possible, for example, to estimate the force transmissibility matrix with the structure off its supports, in free boundary conditions, and without measuring the forces. As far as force identification is concerned, this novel approach significantly decreases the computational effort when compared to conventional approaches, as it requires only local information of the sets of coordinates involved. Numerical simulations and experimental examples are presented and discussed, to illustrate the proposed developments.

Application of atomic force microscopy to microbial surfaces: from reconstituted cell surface layers to living cells.

PubMed

Dufrêne, Y F

2001-02-01

The application of atomic force microscopy (AFM) to probe the ultrastructure and physical properties of microbial cell surfaces is reviewed. The unique capabilities of AFM can be summarized as follows: imaging surface topography with (sub)nanometer lateral resolution; examining biological specimens under physiological conditions; measuring local properties and interaction forces. AFM is being used increasingly for: (i) visualizing the surface ultrastructure of microbial cell surface layers, including bacterial S-layers, purple membranes, porin OmpF crystals and fungal rodlet layers; (ii) monitoring conformational changes of individual membrane proteins; (iii) examining the morphology of bacterial biofilms, (iv) revealing the nanoscale structure of living microbial cells, including fungi, yeasts and bacteria, (v) mapping interaction forces at microbial surfaces, such as van der Waals and electrostatic forces, solvation forces, and steric/bridging forces; and (vi) probing the local mechanical properties of cell surface layers and of single cells.

Oscillatory flow in a cone-and-plate bioreactor.

PubMed

Chung, C A; Tzou, M R; Ho, R W

2005-08-01

Motivated by biometric applications, we analyze oscillatory flow in a cone-and-plate geometry. The cone is rotated in a simple harmonic way on a stationary plate. Based on assuming that the angle between the cone and plate is small, we describe the flow analytically by a perturbation method in terms of two small parameters, the Womersley number and the Reynolds number, which account for the influences of the local acceleration and centripetal force, respectively. Working equations for the shear stresses induced both by laminar primary and secondary flows on the plate surface are presented.

Stress Response of Granular Systems

NASA Astrophysics Data System (ADS)

Ramola, Kabir; Chakraborty, Bulbul

2017-10-01

We develop a framework for stress response in two dimensional granular media, with and without friction, that respects vector force balance at the microscopic level. We introduce local gauge degrees of freedom that determine the response of contact forces between constituent grains on a given, disordered, contact network, to external perturbations. By mapping this response to the spectral properties of the graph Laplacian corresponding to the underlying contact network, we show that this naturally leads to spatial localization of forces. We present numerical evidence for localization using exact diagonalization studies of network Laplacians of soft disk packings. Finally, we discuss the role of other constraints, such as torque balance, in determining the stability of a granular packing to external perturbations.

Prediction of forces and moments for flight vehicle control effectors: Workplan

NASA Technical Reports Server (NTRS)

Maughmer, Mark D.

1989-01-01

Two research activities directed at hypersonic vehicle configurations are currently underway. The first involves the validation of a number of classical local surface inclination methods commonly employed in preliminary design studies of hypersonic flight vehicles. Unlike studies aimed at validating such methods for predicting overall vehicle aerodynamics, this effort emphasizes validating the prediction of forces and moments for flight control studies. Specifically, several vehicle configurations for which experimental or flight-test data are available are being examined. By comparing the theoretical predictions with these data, the strengths and weaknesses of the local surface inclination methods can be ascertained and possible improvements suggested. The second research effort, of significance to control during take-off and landing of most proposed hypersonic vehicle configurations, is aimed at determining the change due to ground effect in control effectiveness of highly swept delta planforms. Central to this research is the development of a vortex-lattice computer program which incorporates an unforced trailing vortex sheet and an image ground plane. With this program, the change in pitching moment of the basic vehicle due to ground proximity, and whether or not there is sufficient control power available to trim, can be determined. In addition to the current work, two different research directions are suggested for future study. The first is aimed at developing an interactive computer program to assist the flight controls engineer in determining the forces and moments generated by different types of control effectors that might be used on hypersonic vehicles. The first phase of this work would deal in the subsonic portion of the flight envelope, while later efforts would explore the supersonic/hypersonic flight regimes. The second proposed research direction would explore methods for determining the aerodynamic trim drag of a generic hypersonic flight vehicle and ways in which it can be minimized through vehicle design and trajectory optimization.

3 CFR - White House Task Force on Middle-Class Working Families

Code of Federal Regulations, 2010 CFR

2010-01-01

... 3 The President 1 2010-01-01 2010-01-01 false White House Task Force on Middle-Class Working... Task Force on Middle-Class Working Families Memorandum for the Heads of Executive Departments and... times. To these ends, I hereby direct the following: Section 1. White House Task Force on Middle-Class...

Dental work force strategies during a period of change and uncertainty.

PubMed

Brown, L J

2001-12-01

Both supply and demand influence the ability of the dental work force to adequately and efficiently provide dental care to a U.S. population growing in size and diversity. Major changes are occurring on both sides of the dental care market. Among factors shaping the demand for dental care are changing disease patterns, shifting population demographics, the extent and features of third-party payment, and growth of the economy and the population. The capacity of the dental work force to provide care is influenced by enhancements of productivity and numbers of dental health personnel, as well as their demographic and practice characteristics. The full impact of these changes is difficult to predict. The dentist-to-population ratio does not reflect all the factors that must be considered to develop an effective dental work force policy. Nationally, the dental work force is likely to be adequate for the next several years, but regional work force imbalances appear to exist and may get worse. Against this backdrop of change and uncertainty, future dental work force strategies should strive for short-term responsiveness while avoiding long-term inflexibility. Trends in the work force must be continually monitored. Thorough analysis is required, and action should be taken when necessary.

Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism.

PubMed

Riveline, D; Zamir, E; Balaban, N Q; Schwarz, U S; Ishizaki, T; Narumiya, S; Kam, Z; Geiger, B; Bershadsky, A D

2001-06-11

The transition of cell-matrix adhesions from the initial punctate focal complexes into the mature elongated form, known as focal contacts, requires GTPase Rho activity. In particular, activation of myosin II-driven contractility by a Rho target known as Rho-associated kinase (ROCK) was shown to be essential for focal contact formation. To dissect the mechanism of Rho-dependent induction of focal contacts and to elucidate the role of cell contractility, we applied mechanical force to vinculin-containing dot-like adhesions at the cell edge using a micropipette. Local centripetal pulling led to local assembly and elongation of these structures and to their development into streak-like focal contacts, as revealed by the dynamics of green fluorescent protein-tagged vinculin or paxillin and interference reflection microscopy. Inhibition of Rho activity by C3 transferase suppressed this force-induced focal contact formation. However, constitutively active mutants of another Rho target, the formin homology protein mDia1 (Watanabe, N., T. Kato, A. Fujita, T. Ishizaki, and S. Narumiya. 1999. Nat. Cell Biol. 1:136-143), were sufficient to restore force-induced focal contact formation in C3 transferase-treated cells. Force-induced formation of the focal contacts still occurred in cells subjected to myosin II and ROCK inhibition. Thus, as long as mDia1 is active, external tension force bypasses the requirement for ROCK-mediated myosin II contractility in the induction of focal contacts. Our experiments show that integrin-containing focal complexes behave as individual mechanosensors exhibiting directional assembly in response to local force.

Prehension Synergies in the Grasps With Complex Friction Patterns: Local Versus Synergic Effects and the Template Control

PubMed Central

Niu, Xun; Latash, Mark L.; Zatsiorsky, Vladimir M.

2010-01-01

We studied adjustments of digit forces to changes in the friction. The subjects held a handle statically in a three-digit grasp. The friction under each digit was either high or low, resulting in eight three-element friction sets (such grasps were coined the grasps with complex friction pattern). The total load was also manipulated. It was found that digit forces were adjusted not only to the supported load and local friction, but also to friction at other digits (synergic effects). When friction under a digit was low, its tangential force decreased and the normal force increased (local effects). The synergic effects were directed to maintain the equilibrium of the handle. The relation between the individual digit forces and loads agreed with the triple-product model: fin=ki(2)ki(1)L, where fin is normal force of digit i, L is the load (newtons), ki(1) is a dimensionless coefficient representing sharing the total tangential force among the digits (Σki(1)=1.0), and ki(2) is a coefficient representing the relation between the tangential and normal forces of digit i (the overall friction equivalent, OFE). At each friction set, the central controller selected the grasping template—a three-element array of ki(2)ki(1) products—and then scaled the template with the load magnitude. PMID:17493928

Understanding shape entropy through local dense packing

DOE PAGES

van Anders, Greg; Klotsa, Daphne; Ahmed, N. Khalid; ...

2014-10-24

Entropy drives the phase behavior of colloids ranging from dense suspensions of hard spheres or rods to dilute suspensions of hard spheres and depletants. Entropic ordering of anisotropic shapes into complex crystals, liquid crystals, and even quasicrystals was demonstrated recently in computer simulations and experiments. The ordering of shapes appears to arise from the emergence of directional entropic forces (DEFs) that align neighboring particles, but these forces have been neither rigorously defined nor quantified in generic systems. In this paper, we show quantitatively that shape drives the phase behavior of systems of anisotropic particles upon crowding through DEFs. We definemore » DEFs in generic systems and compute them for several hard particle systems. We show they are on the order of a few times the thermal energy (k BT) at the onset of ordering, placing DEFs on par with traditional depletion, van der Waals, and other intrinsic interactions. In experimental systems with these other interactions, we provide direct quantitative evidence that entropic effects of shape also contribute to self-assembly. We use DEFs to draw a distinction between self-assembly and packing behavior. We show that the mechanism that generates directional entropic forces is the maximization of entropy by optimizing local particle packing. Finally, we show that this mechanism occurs in a wide class of systems and we treat, in a unified way, the entropy-driven phase behavior of arbitrary shapes, incorporating the well-known works of Kirkwood, Onsager, and Asakura and Oosawa.« less

Measuring localized viscoelasticity of the vitreous body using intraocular microprobes.

PubMed

Pokki, Juho; Ergeneman, Olgaç; Sevim, Semih; Enzmann, Volker; Torun, Hamdi; Nelson, Bradley J

2015-10-01

Vitrectomy is a standard ophthalmic procedure to remove the vitreous body from the eye. The biomechanics of the vitreous affects its duration (by changing the removal rate) and the mechanical forces transmitted via the vitreous on the surrounding tissues during the procedure. Biomechanical characterization of the vitreous is essential for optimizing the design and control of instruments that operate within the vitreous for improved precision, safety, and efficacy. The measurements are carried out using a magnetic microprobe inserted into the vitreous, a method known as magnetic microrheology. The location of the probe is tracked by a microscope/camera while magnetic forces are exerted wirelessly by applied magnetic fields. In this work, in vitro artificial vitreous, ex vivo human vitreous and ex vivo porcine vitreous were characterized. In addition, in vivo rabbit measurements were performed using a suturelessly injected probe. Measurements indicate that viscoelasticity parameters of the ex vivo human vitreous are an order of magnitude different from those of the ex vivo porcine vitreous. The in vivo intra-operative measurements show typical viscoelastic behavior of the vitreous with a lower compliance than the ex vivo measurements. The results of the magnetic microrheology measurements were validated with those obtained by a standard atomic force microscopy (AFM) method and in vitro artificial vitreous. This method allows minimally-invasive characterization of localized mechanical properties of the vitreous in vitro, ex vivo, and in vivo. A better understanding of the characteristics of the vitreous can lead to improvements in treatments concerning vitreal manipulation such as vitrectomy.

Rise and fall of competitiveness in individualistic and collectivistic societies

PubMed Central

Leibbrandt, Andreas; Gneezy, Uri; List, John A.

2013-01-01

Competitiveness pervades life: plants compete for sunlight and water, animals for territory and food, and humans for mates and income. Herein we investigate human competitiveness with a natural experiment and a set of behavioral experiments. We compare competitiveness in traditional fishing societies where local natural forces determine whether fishermen work in isolation or in collectives. We find sharp evidence that fishermen from individualistic societies are far more competitive than fishermen from collectivistic societies, and that this difference emerges with work experience. These findings suggest that humans can evolve traits to specific needs, support the idea that socio-ecological factors play a decisive role for individual competitiveness, and provide evidence how individualistic and collectivistic societies shape economic behavior. PMID:23696669

Decoding gripping force based on local field potentials recorded from subthalamic nucleus in humans

PubMed Central

Tan, Huiling; Pogosyan, Alek; Ashkan, Keyoumars; Green, Alexander L; Aziz, Tipu; Foltynie, Thomas; Limousin, Patricia; Zrinzo, Ludvic; Hariz, Marwan; Brown, Peter

2016-01-01

The basal ganglia are known to be involved in the planning, execution and control of gripping force and movement vigour. Here we aim to define the nature of the basal ganglia control signal for force and to decode gripping force based on local field potential (LFP) activities recorded from the subthalamic nucleus (STN) in patients with deep brain stimulation (DBS) electrodes. We found that STN LFP activities in the gamma (55–90 Hz) and beta (13–30m Hz) bands were most informative about gripping force, and that a first order dynamic linear model with these STN LFP features as inputs can be used to decode the temporal profile of gripping force. Our results enhance the understanding of how the basal ganglia control gripping force, and also suggest that deep brain LFPs could potentially be used to decode movement parameters related to force and movement vigour for the development of advanced human-machine interfaces. DOI: http://dx.doi.org/10.7554/eLife.19089.001 PMID:27855780

Knee Cartilage Thickness, T1ρ and T2 Relaxation Time Are Related to Articular Cartilage Loading in Healthy Adults

PubMed Central

Van Rossom, Sam; Smith, Colin Robert; Zevenbergen, Lianne; Thelen, Darryl Gerard; Vanwanseele, Benedicte; Van Assche, Dieter; Jonkers, Ilse

2017-01-01

Cartilage is responsive to the loading imposed during cyclic routine activities. However, the local relation between cartilage in terms of thickness distribution and biochemical composition and the local contact pressure during walking has not been established. The objective of this study was to evaluate the relation between cartilage thickness, proteoglycan and collagen concentration in the knee joint and knee loading in terms of contact forces and pressure during walking. 3D gait analysis and MRI (3D-FSE, T1ρ relaxation time and T2 relaxation time sequence) of fifteen healthy subjects were acquired. Experimental gait data was processed using musculoskeletal modeling to calculate the contact forces, impulses and pressure distribution in the tibiofemoral joint. Correlates to local cartilage thickness and mean T1ρ and T2 relaxation times of the weight-bearing area of the femoral condyles were examined. Local thickness was significantly correlated with local pressure: medial thickness was correlated with medial condyle contact pressure and contact force, and lateral condyle thickness was correlated with lateral condyle contact pressure and contact force during stance. Furthermore, average T1ρ and T2 relaxation time correlated significantly with the peak contact forces and impulses. Increased T1ρ relaxation time correlated with increased shear loading, decreased T1ρ and T2 relaxation time correlated with increased compressive forces and pressures. Thicker cartilage was correlated with higher condylar loading during walking, suggesting that cartilage thickness is increased in those areas experiencing higher loading during a cyclic activity such as gait. Furthermore, the proteoglycan and collagen concentration and orientation derived from T1ρ and T2 relaxation measures were related to loading. PMID:28076431

Grasp Assist Device with Automatic Mode Control Logic

NASA Technical Reports Server (NTRS)

Laske, Evan (Inventor); Davis, Donald R. (Inventor); Ihrke, Chris A. (Inventor)

2018-01-01

A system includes a glove, sensors, actuator assemblies, and controller. The sensors include load sensors which measure an actual grasping force and attitude sensors which determine a glove attitude. The actuator assembly provides a grasp assist force to the glove. Respective locations of work cells in the work environment and permitted work tasks for each work cell are programmed into the controller. The controller detects the glove location and attitude. A work task is selected by the controller for the location. The controller calculates a required grasp assist force using measured actual grasping forces from the load sensors. The required grasp assist force is applied via the glove using the actuator assembly to thereby assist the operator in performing the identified work task.

Work Optimization Predicts Accretionary Faulting: An Integration of Physical and Numerical Experiments

NASA Astrophysics Data System (ADS)

McBeck, Jessica A.; Cooke, Michele L.; Herbert, Justin W.; Maillot, Bertrand; Souloumiac, Pauline

2017-09-01

We employ work optimization to predict the geometry of frontal thrusts at two stages of an evolving physical accretion experiment. Faults that produce the largest gains in efficiency, or change in external work per new fault area, ΔWext/ΔA, are considered most likely to develop. The predicted thrust geometry matches within 1 mm of the observed position and within a few degrees of the observed fault dip, for both the first forethrust and backthrust when the observed forethrust is active. The positions of the second backthrust and forethrust that produce >90% of the maximum ΔWext/ΔA also overlap the observed thrusts. The work optimal fault dips are within a few degrees of the fault dips that maximize the average Coulomb stress. Slip gradients along the detachment produce local elevated shear stresses and high strain energy density regions that promote thrust initiation near the detachment. The mechanical efficiency (Wext) of the system decreases at each of the two simulated stages of faulting and resembles the evolution of experimental force. The higher ΔWext/ΔA due to the development of the first pair relative to the second pair indicates that the development of new thrusts may lead to diminishing efficiency gains as the wedge evolves. The numerical estimates of work consumed by fault propagation overlap the range calculated from experimental force data and crustal faults. The integration of numerical and physical experiments provides a powerful approach that demonstrates the utility of work optimization to predict the development of faults.

State Workforce Policy Initiative.

ERIC Educational Resources Information Center

Public/Private Ventures, Philadelphia, PA.

Surging demand for workers, growing income inequality, and passage of welfare reforms have made work force development one of the United States' key national concerns. Public/Private Ventures has been working with various states to design work force development strategies that seek to address the concerns of many work force development specialists…

Analysis of the polar amplification pattern of global warming on an aquaplanet in "ghost forcing" experiments with no ice-albedo feedbacks

NASA Astrophysics Data System (ADS)

Alexeev, V. A.; Langen, P. L.

2004-05-01

Non-ice-albedo feedback mechanisms leading to polar amplification, as reported by Alexeev (2003), are explored in three aquaplanet climate model systems of different complexity. We analyze this pattern using three different "ghost forcing" experiments (Hansen et al, 1997). In the first one we uniformly add 4W/m2 to the oceanic mixed layer in order to roughly simulate a 2xCO2 forcing at the surface. The second forcing, of the same magnitude, is applied only within the tropics and the third forcing is applied only polewards of 30 degrees (north and south). It turns out that our systems' equilibrium responses are linear with respect to these forcings. Surprisingly, the response to the tropical-only forcing is essentially non-local with quite significant warming at higher latitudes. The response to the high-latitude-only forcing is more local and has higher amplitude near the poles. Our explanation of the polar amplification obtained in the uniform forcing experiment is therefore two-fold. Firstly, the tropics are much more difficult to warm because of the higher sensitivity of the surface budget to SST changes at higher temperatures. Secondly, any extra heat deposited in the tropics is not easily radiated to outer space because of the high opaqueness of the tropical atmosphere. The energy, most of which is latent, needs to be redistributed by transports to the extra-tropics. Consequently, the tropical "ghost forcing" results in an essentially non-local response, while the extra-tropical one yields a more localized response, because the energy in the atmosphere cannot propagate effectively equator-wards from high latitudes. The paper deals with these mechanisms in three climate model systems with no ice-albedo feedback - an EBM and two different GCMs - one with cloud feedbacks and the other with cloud feedbacks excluded. References. Alexeev, V.A., (2003) Sensitivity to CO2 doubling of an atmospheric GCM coupled to an oceanic mixed layer: a linear analysis. Climate Dynamics, 20: p.775-787. Hansen, J., Sato M, and R. Ruedy, (1997) Radiative forcing and climate response, JGR, 102, No. D6, 6831-6864.

Alongshore Momentum Balance Over Shoreface-Connected Ridges, Fire Island, NY

NASA Astrophysics Data System (ADS)

Ofsthun, C.; Wu, X.; Voulgaris, G.; Warner, J. C.

2016-12-01

he momentum balance of alongshore flows over straight, uniform shelfs has been analyzed extensively over the last few decades. More recently, the effect of coastline curvature and how this might alter the relative significance of the momentum terms has received additional attention. In this contribution, the alongshore momentum over shelves with straight coastline, but non-uniform bathymetry is examined. Hydrodynamic and hydrographic data collected by the US Geological Survey (Fire Island Coastal Change project) on the inner shelf of Fire Island, NY over a region of shore-face connected ridges (SFCRs) are used to describe wind-induced circulation and the terms of the alongshore momentum balance equation. Analysis of the data revealed a predominantly alongshore circulation, under westward wind forcing, with localized offshore (onshore) current veering over the ridge crests (troughs). Momentum balance analysis hinted that local acceleration, advective acceleration, and bottom stress are balanced by wind stress and regional (>100 km) pressure gradient force. In addition, a numerical model using an idealized SFCR bathymetry, forced by our observed winds, was employed to compare the momentum balance relationships identified by the data and those under steady-state conditions published earlier (Warner et al., 2014). A synthesis of the numerical and experimental data revealed that the true pressure gradient force results from the sum of local pressure gradient force, which maintains a Bernoulli-like relationship with alongshore advective acceleration, and regional pressure gradient force, which maintains a strong, negative relationship with wind stress. The differences between steady-state and realistic conditions is mainly on the contributions of regional scale pressure gradients that develop under realistic conditions, and the reduced contribution of local scale pressure gradients which develop best under steady-state conditions. Our analysis indicates that current veering over ridge crests, a consistent occurrence, is a combination of a cross-shore gradient in the inconsistent relationship between local advective acceleration and pressure gradient and frictional-torque with the latter being the dominant mechanism under realistic forcing.

Factors associated with forced sex among women accessing health services in rural Haiti: implications for the prevention of HIV infection and other sexually transmitted diseases.

PubMed

Smith Fawzi, M C; Lambert, W; Singler, J M; Tanagho, Y; Léandre, F; Nevil, P; Bertrand, D; Claude, M S; Bertrand, J; Louissaint, M; Jeannis, L; Mukherjee, J S; Goldie, S; Salazar, J J; Farmer, P E

2005-02-01

The goals of the current study were to: (1) estimate the prevalence of forced sex among women accessing services at a women's health clinic in rural Haiti; and (2) examine factors associated with forced sex in this population. Based on data from a case-control study of risk factors for sexually transmitted diseases (STDs), a cross-sectional analysis to examine factors associated with forced sex was performed. A number of factors related to gender inequality/socioeconomic vulnerability placed women in rural Haiti at higher risk of forced sex. The strongest factors associated with forced sex in multivariate analyses were: age, length of time in a relationship, occupation of the woman's partner, STD-related symptoms, and factors demonstrating economic vulnerability. The findings suggest that prevention efforts must go beyond provision of information and education to the pursuit of broader initiatives at both local and national levels. At the community level, policy-makers should consider advancing economic opportunities for women who are vulnerable to forced sex. Improving access to community-based income-generating activities may begin to address this problem. However, the viability of these local projects depends largely upon Haiti's 'macro-economic' situation. In order to ensure the success of local initiatives, external humanitarian and development assistance to Haiti should be supported. By broadening the definition of "prevention" interventions, we may begin to address the systemic problems that contribute to the occurrence of forced sex and the increasing incidence of HIV infection throughout the world, such as gender inequality and economic vulnerability. Taking into account factors influencing risk at the local level as well as the macro-level will potentially improve our capacity to reduce the risk of forced sex and the spread of STDs, including HIV infection, for millions of women living in poverty worldwide.

Local electric dipole moments: A generalized approach.

PubMed

Groß, Lynn; Herrmann, Carmen

2016-09-30

We present an approach for calculating local electric dipole moments for fragments of molecular or supramolecular systems. This is important for understanding chemical gating and solvent effects in nanoelectronics, atomic force microscopy, and intensities in infrared spectroscopy. Owing to the nonzero partial charge of most fragments, "naively" defined local dipole moments are origin-dependent. Inspired by previous work based on Bader's atoms-in-molecules (AIM) partitioning, we derive a definition of fragment dipole moments which achieves origin-independence by relying on internal reference points. Instead of bond critical points (BCPs) as in existing approaches, we use as few reference points as possible, which are located between the fragment and the remainder(s) of the system and may be chosen based on chemical intuition. This allows our approach to be used with AIM implementations that circumvent the calculation of critical points for reasons of computational efficiency, for cases where no BCPs are found due to large interfragment distances, and with local partitioning schemes other than AIM which do not provide BCPs. It is applicable to both covalently and noncovalently bound systems. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Impact of heat and water management on proton exchange membrane fuel cells degradation in automotive application

NASA Astrophysics Data System (ADS)

Nandjou, F.; Poirot-Crouvezier, J.-P.; Chandesris, M.; Blachot, J.-F.; Bonnaud, C.; Bultel, Y.

2016-09-01

In Proton Exchange Membrane Fuel Cells, local temperature is a driving force for many degradation mechanisms such as hygrothermal deformation and creep of the membrane, platinum dissolution and bipolar plates corrosion. In order to investigate and quantify those effects in automotive application, durability testing is conducted in this work. During the ageing tests, the local performance and temperature are investigated using in situ measurements of a printed circuit board. At the end of life, post-mortem analyses of the aged components are conducted. The experimental results are compared with the simulated temperature and humidity in the cell obtained from a pseudo-3D multiphysics model in order to correlate the observed degradations to the local conditions inside the stack. The primary cause of failure in automotive cycling is pinhole/crack formation in the membrane, induced by high variations of its water content over time. It is also observed that water condensation largely increases the probability of the bipolar plates corrosion while evaporation phenomena induce local deposits in the cell.

Geometrical Origins of Contractility in Disordered Actomyosin Networks

NASA Astrophysics Data System (ADS)

Lenz, Martin

2014-10-01

Movement within eukaryotic cells largely originates from localized forces exerted by myosin motors on scaffolds of actin filaments. Although individual motors locally exert both contractile and extensile forces, large actomyosin structures at the cellular scale are overwhelmingly contractile, suggesting that the scaffold serves to favor contraction over extension. While this mechanism is well understood in highly organized striated muscle, its origin in disordered networks such as the cell cortex is unknown. Here, we develop a mathematical model of the actin scaffold's local two- or three-dimensional mechanics and identify four competing contraction mechanisms. We predict that one mechanism dominates, whereby local deformations of the actin break the balance between contraction and extension. In this mechanism, contractile forces result mostly from motors plucking the filaments transversely rather than buckling them longitudinally. These findings shed light on recent in vitro experiments and provide a new geometrical understanding of contractility in the myriad of disordered actomyosin systems found in vivo.

Agricultural Work Force Households: How Much Do They Depend on Farming? Background for Agricultural Policy. Agriculture Information Bulletin Number 547.

ERIC Educational Resources Information Center

Cox, E. Jane; Oliveira, Victor J.

According to data from the 1985 Agricultural Work Force Survey, over 13.5 million of the 17.6 million agricultural work force household members (77 percent) lived in households headed by a farm worker. Some farm workers worked on the farm as their primary job, whereas others primarily worked off the farm. Farm work was an occasional form of…

Design and Optimization of Nanomaterials for Sensing Applications

NASA Astrophysics Data System (ADS)

Sanderson, Robert Noboru

Nanomaterials, materials with one or more of their dimensions on the nanoscale, have emerged as an important field in the development of next-generation sensing systems. Their high surface-to-volume ratio makes them useful for sensing, but also makes them sensitive to processing defects and inherent material defects. To develop and optimize these systems, it is thus necessary to characterize these defects to understand their origin and how to work around them. Scanning probe microscopy (SPM) techniques like atomic force microscopy (AFM) and scanning tunneling microscopy (STM) are important characterization methods which can measure nanoscale topography and electronic structure. These methods are appealing in nanomaterial systems because they are non-damaging and provide local, high-resolution data, and so are capable of detecting nanoscale features such as single defect sites. There are difficulties, however, in the interpretation of SPM data. For instance, AFM-based methods are prone to experimental artifacts due to long-range interactions, such as capacitive crosstalk in Kelvin probe force microscopy (KPFM), and artifacts due to the finite size of the probe tip, such as incorrect surface tracking at steep topographical features. Mechanical characterization (via force spectroscopy) of nanomaterials with significant nanoscale variations, such as tethered lipid bilayer membranes (tLBMs), is also difficult since variations in the bulk system's mechanical behavior must be distinguished from local fluctuations. Additionally, interpretation of STM data is non-trivial due to local variations in electron density in addition to topographical variations. In this thesis we overcome some limitations of SPM methods by supplementing them with additional surface analytical methods as well as computational methods, and we characterize several nanomaterial systems. Current-carrying vapor-liquid-solid Si nanowires (useful for interdigitated-electrode-based sensors) are characterized using finite-element-method (FEM)-supplemented KPFM to retrieve useful information about processing defects, contact resistance, and the primary charge carriers. Next, a tLBM system's stiffness and the stiffness' dependence on tethering molecule concentration is measured using statistical analysis of thousands of AFM force spectra, demonstrating a biosensor-compatible system with a controllable bulk rigidity. Finally, we utilize surface analytical techniques to inform the development of a novel three-dimensional graphene system for sensing applications.

Scanning thermo-ionic microscopy for probing local electrochemistry at the nanoscale

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eshghinejad, Ahmadreza; Nasr Esfahani, Ehsan; Wang, Peiqi

2016-05-28

Conventional electrochemical characterization techniques based on voltage and current measurements only probe faradaic and capacitive rates in aggregate. In this work we develop a scanning thermo-ionic microscopy (STIM) to probe local electrochemistry at the nanoscale, based on imaging of Vegard strain induced by thermal oscillation. It is demonstrated from both theoretical analysis and experimental validation that the second harmonic response of thermally induced cantilever vibration, associated with thermal expansion, is present in all solids, whereas the fourth harmonic response, caused by local transport of mobile species, is only present in ionic materials. The origin of STIM response is further confirmedmore » by its reduced amplitude with respect to increased contact force, due to the coupling of stress to concentration of ionic species and/or electronic defects. The technique has been applied to probe Sm-doped Ceria and LiFePO{sub 4}, both of which exhibit higher concentrations of mobile species near grain boundaries. The STIM gives us a powerful method to study local electrochemistry with high sensitivity and spatial resolution for a wide range of ionic systems, as well as ability to map local thermomechanical response.« less

Diversity in the Work Force. The Highlight Zone: Research @ Work No. 4.

ERIC Educational Resources Information Center

Wentling, Rose Mary

A literature review was conducted to identify critical work force diversity issues in today's changing workplace and identify ways organizations and career and technical education (CTE) practitioners can increase work force diversity. A broad, all-inclusive definition of diversity was developed that focuses on how diversity affects individuals and…

Physical Model of the Dynamic Instability in an Expanding Cell Culture

PubMed Central

Mark, Shirley; Shlomovitz, Roie; Gov, Nir S.; Poujade, Mathieu; Grasland-Mongrain, Erwan; Silberzan, Pascal

2010-01-01

Abstract Collective cell migration is of great significance in many biological processes. The goal of this work is to give a physical model for the dynamics of cell migration during the wound healing response. Experiments demonstrate that an initially uniform cell-culture monolayer expands in a nonuniform manner, developing fingerlike shapes. These fingerlike shapes of the cell culture front are composed of columns of cells that move collectively. We propose a physical model to explain this phenomenon, based on the notion of dynamic instability. In this model, we treat the first layers of cells at the front of the moving cell culture as a continuous one-dimensional membrane (contour), with the usual elasticity of a membrane: curvature and surface-tension. This membrane is active, due to the forces of cellular motility of the cells, and we propose that this motility is related to the local curvature of the culture interface; larger convex curvature correlates with a stronger cellular motility force. This shape-force relation gives rise to a dynamic instability, which we then compare to the patterns observed in the wound healing experiments. PMID:20141748

Post-Traumatic Stress Disorder among French Armed Forces Members in Afghanistan: A New Approach.

PubMed

Paul, Frédéric; Marimoutou, Catherine; Pommier de Santi, Vincent; Clervoy, Patrick

2016-01-01

During the 20th century, the management of war-related psychological trauma shifted from neurology to psychiatry. After September 11, 2001, the French forces participated in a multinational force deployed in Afghanistan to fight against terrorism. Post-traumatic stress disorder (PTSD) became a priority. We report the daily work of the psychiatrists involved in this mission and the organization developed to psychologically support wounded military personnel. The doctrine of early intervention psychiatrization and the technique of collective debriefing are the key points of this procedure. The psychiatrist is also responsible for the healthcare community, particularly vulnerable when confronted with severe ballistic injuries. One aim of this organization is also to screen PTSD in soldiers returning from Afghanistan. The military general practitioner is a pivotal point of this procedure built to detect PTSD, anxiety, depressive reaction and behavioral problems. The French health service has developed a genuine care strategy aimed at identifying patients, accompanying them in the formalities for recognition and compensation, and offering them treatment locally by arranging clinical psychology consultations near their home. © 2016 S. Karger AG, Basel.

Structure and local charging of electromigrated Au nanocontacts

NASA Astrophysics Data System (ADS)

Arnold, D.; Marz, M.; Schneider, S.; Hoffmann-Vogel, R.

2017-02-01

We study the structure and the electronic properties of Au nanocontacts created by controlled electromigration of thin film devices, a method frequently used to contact molecules. In contrast to electromigration testing, a current is applied in a cyclic fashion and during each cycle the resistance increase of the metal upon heating is used to avoid thermal runaway. In this way, nanometer sized-gaps are obtained. The thin film devices with an optimized structure at the origin of the electromigration process are made by shadow evaporation without contamination by organic materials. Defining rounded edges and a thinner area in the center of the device allow to pre-determine the location where the electromigration takes place. Scanning force microscopy images of the pristine Au film and electromigrated contact show its grainy structure. Through electromigration, a 1.5 μm-wide slit is formed, with extensions only on the anode side that had previously not been observed in narrower structures. It is discussed whether this could be explained by asymmetric heating of both electrodes. New grains are formed in the slit and on the extensions on both, the anode and the cathode side. The smaller structures inside the slit lead to an electrode distance below 150 nm. Kelvin probe force microscopy images show a local work function difference with fluctuations of 70 mV on the metal before electromigration. Between the electrodes, disconnected through electromigration, a work function difference of 3.2 V is observed due to charging. Some of the grains newly formed by electromigration are electrically disconnected from the electrodes.

Transcription upregulation via force-induced direct stretching of chromatin

NASA Astrophysics Data System (ADS)

Tajik, Arash; Zhang, Yuejin; Wei, Fuxiang; Sun, Jian; Jia, Qiong; Zhou, Wenwen; Singh, Rishi; Khanna, Nimish; Belmont, Andrew S.; Wang, Ning

2016-12-01

Mechanical forces play critical roles in the function of living cells. However, the underlying mechanisms of how forces influence nuclear events remain elusive. Here, we show that chromatin deformation as well as force-induced transcription of a green fluorescent protein (GFP)-tagged bacterial-chromosome dihydrofolate reductase (DHFR) transgene can be visualized in a living cell by using three-dimensional magnetic twisting cytometry to apply local stresses on the cell surface via an Arg-Gly-Asp-coated magnetic bead. Chromatin stretching depended on loading direction. DHFR transcription upregulation was sensitive to load direction and proportional to the magnitude of chromatin stretching. Disrupting filamentous actin or inhibiting actomyosin contraction abrogated or attenuated force-induced DHFR transcription, whereas activating endogenous contraction upregulated force-induced DHFR transcription. Our findings suggest that local stresses applied to integrins propagate from the tensed actin cytoskeleton to the LINC complex and then through lamina-chromatin interactions to directly stretch chromatin and upregulate transcription.

Lagrangian Fluid Element Tracking and Estimation of Local Displacement Speeds in Turbulent Premixed Flames

NASA Astrophysics Data System (ADS)

Ramji, Sarah Ann

Improved understanding of turbulence-flame interactions in premixed combustion can be achieved using fully 3D time-resolved multi-kHz multi-scalar experimental measurements. These interactions may be represented by the evolution of various Lagrangian quantities described by theoretical Lagrangian Fluid Elements (LFEs). The data used in this work came from two experimental campaigns that used simultaneous T-PIV and OH/CH2O PLIF, at Sandia National Labs and the Air Force Research Lab at Wright-Patterson. In this thesis, an algorithm to accurately track LFEs through this 4D experimental space has been developed and verified by cross-correlation with the T-PIV seed particle fields. A novel method to measure the local instantaneous displacement speed in 3D has been developed, using this algorithm to track control masses of fluid that interact with the flame front. Statistics of the displacement speed have been presented, and the effects of local turbulence and flame topological properties on the displacement speed have been studied.

Evaluation of knee joint forces during kneeling work with different kneepads.

PubMed

Xu, Hang; Jampala, Sree; Bloswick, Donald; Zhao, Jie; Merryweather, Andrew

2017-01-01

The main purpose of this study is to determine knee joint forces resulting from kneeling work with and without kneepads to quantify how different kneepads redistribute force. Eleven healthy males simulated a tile setting task to different locations during six kneepad states (five different kneepad types and without kneepad). Peak and average forces on the anatomical landmarks of both knees were obtained by custom force sensors. The results revealed that kneepad design can significantly modify the forces on the knee joint through redistribution. The Professional Gel design was preferred among the five tested kneepads which was confirmed with both force measurements and participants' responses. The extreme reaching locations induced significantly higher joint forces on left knee or right knee depending on task. The conclusion of this study is that a properly selected kneepad for specific tasks and a more neutral working posture can modify the force distribution on the knees and likely decrease the risk of knee disorders from kneeling work. Copyright © 2016 Elsevier Ltd. All rights reserved.

Data-driven local-scale modeling of ionospheric responses to auroral forcing using incoherent scatter radar and ground-based imaging measurements

NASA Astrophysics Data System (ADS)

Grubbs, G. A., II; Zettergren, M. D.; Samara, M.; Michell, R.; Hampton, D. L.; Lynch, K. A.; Varney, R. H.; Reimer, A.; Burleigh, M.

2017-12-01

The aurora encapsulates a wide range of spatial and temporal scale sizes, particularly during active events such as those that exist during substorm expansion. Of interest to the present work are ionospheric responses to magnetospheric forcing at relatively small scales (0.5-20 km), including formation of structured auroral arc current systems, ion frictional heating, upflow, and density cavity formation among other processes. Even for carefully arranged experiments, it is often difficult to fully assess physical details (time evolution, causality, unobservable parameters) associated with these types of responses, thus highlighting the general need for high-resolution modeling efforts to support the observations. In this work, we develop and test a local-scale model to describe effects of precipitating electrons and electric fields on the ionospheric plasma responses using available remote sensing data (e.g. from ISRs and filtered cameras). Our model is based on a 3D multi-fluid/electrostatic ionospheric model, GEMINI (Zettergren et al., 2015), coupled a two-stream electron transport code which produces auroral intensities, impact ionization, and thermal electron heating GLobal airglOW (GLOW; Solomon, 2017). GEMINI-GLOW thus describes both thermal and suprathermal effects on the ionosphere and is driven by boundary conditions consisting of topside ionospheric field-aligned currents and suprathermal electrons. These boundary conditions are constrained using time and space-dependent electric field and precipitation estimates from recent sounding rocket campaigns, ISINGLASS (02 March 2017) and GREECE (03 March 2014), derived from the Poker Flat incoherent scatter radar (PFISR) drifts and filtered EMCCD cameras respectively. Results from these data-driven case studies are compared to plasma parameter responses (i.e. density and temperature) independently estimated by PFISR and from the sounding rockets. These studies are intended as a first step towards a local-scale assimilative modeling approach where data-derived information will be fed back into the model to update the system state.

Deregulation strategies for local governments and the role/opportunities for energy efficiency services in the utility industry deregulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tseng, P.C.

As the future shape of the electric utility industry continues to unfold and as retail competition becomes a reality, local governments are faced with balancing the need for: (1) economic development; (2) and to avoid the potential impact of cost-shifting among residents and businesses, while ensuring reliable and universal energy services. Furthermore, local governments need to find ways to recoup potential loss of franchise and tax revenues, to ensure fair and adequate energy-efficiency programs, and to continue other social programs for low income families. This paper will address two important issues every local government in the US are facing: (1)more » the development of viable deregulation strategies before, during and after the promulgation of utility deregulation; (2) opportunities for energy efficiency services in the competitive markets to serve local governments, which typically constitutes the largest market segment in utility's service territory. This paper presents issues and challenges common to all local governments. It documents strategies that several local governments are utilizing to embrace the coming electric utility restructuring and competition challenge to the benefits of their respective communities. This paper presents the results on deregulation work by the City of Portland, Oregon, Barnstable County, Massachusetts, and Montgomery County, Maryland. The research by these local governments was sponsored by the Urban Consortium Energy Task Force and Public Technology, Inc.« less

A two-step FEM-SEM approach for wave propagation analysis in cable structures

NASA Astrophysics Data System (ADS)

Zhang, Songhan; Shen, Ruili; Wang, Tao; De Roeck, Guido; Lombaert, Geert

2018-02-01

Vibration-based methods are among the most widely studied in structural health monitoring (SHM). It is well known, however, that the low-order modes, characterizing the global dynamic behaviour of structures, are relatively insensitive to local damage. Such local damage may be easier to detect by methods based on wave propagation which involve local high frequency behaviour. The present work considers the numerical analysis of wave propagation in cables. A two-step approach is proposed which allows taking into account the cable sag and the distribution of the axial forces in the wave propagation analysis. In the first step, the static deformation and internal forces are obtained by the finite element method (FEM), taking into account geometric nonlinear effects. In the second step, the results from the static analysis are used to define the initial state of the dynamic analysis which is performed by means of the spectral element method (SEM). The use of the SEM in the second step of the analysis allows for a significant reduction in computational costs as compared to a FE analysis. This methodology is first verified by means of a full FE analysis for a single stretched cable. Next, simulations are made to study the effects of damage in a single stretched cable and a cable-supported truss. The results of the simulations show how damage significantly affects the high frequency response, confirming the potential of wave propagation based methods for SHM.

Possibilities and hindrances for prevention of intimate partner violence: perceptions among professionals and decision makers in a Swedish medium-sized town.

PubMed

Jakobsson, A; von Borgstede, C; Krantz, G; Spak, F; Hensing, G

2013-09-01

Intimate partner violence (IPV) is a major public health problem, but few evidence-based prevention programs have yet been implemented. This study explored the perceptions and beliefs of local-level decision makers, social and health-care professionals, and representatives from the police force regarding the possibilities and hindrances for prevention of IPV. An explorative qualitative approach was used, and participants were strategically selected for focus group discussions. The participants, 19 men and 23 women, were professionals or decision makers within health-care services, social welfare, municipal administration, the police force, local industry, and local politicians in a Swedish town of 54,000 inhabitants. The focus group discussions were audio recorded, transcribed verbatim, and thematically analyzed. A manifest content analysis was performed on the text. Preschools, schools, sports associations, workplaces, and the mass media were suggested as possible arenas for prevention measures. The proposed activities included norm building and improved social support structures. Hindrances were conceptualized as societal beliefs and attitudes, shame, silence, gender inequality, the counteracting influence of the media, and lack of resources. The participants demonstrated closeness and distance to IPV, expressed as acceptance or referral of responsibility to others regarding where and by whom prevention measures should be executed. This study gave new insights in the prevailing perceptions of professionals and decision makers of a medium-sized Swedish town, which can be a useful knowledge in future preventive work and contribute to bridge the gap between research and practice.

Assessing the observed impact of anthropogenic climate change

DOE PAGES

Hansen, Gerrit; Stone, Dáithí

2015-12-21

Impacts of recent regional changes in climate on natural and human systems are documented across the globe, yet studies explicitly linking these observations to anthropogenic forcing of the climate are scarce. Here in this work, we provide a systematic assessment of the role of anthropogenic climate change for the range of impacts of regional climate trends reported in the IPCC’s Fifth Assessment Report. We find that almost two-thirds of the impacts related to atmospheric and ocean temperature can be confidently attributed to anthropogenic forcing. In contrast, evidence connecting changes in precipitation and their respective impacts to human influence is stillmore » weak. Moreover, anthropogenic climate change has been a major influence for approximately three-quarters of the impacts observed on continental scales. Finally, hence the effects of anthropogenic emissions can now be discerned not only globally, but also at more regional and local scales for a variety of natural and human systems.« less

Electrochemically assisted localized etching of ZnO single crystals in water using a catalytically active Pt-coated atomic force microscopy probe

NASA Astrophysics Data System (ADS)

Shibata, Takayuki; Yamamoto, Kota; Sasano, Junji; Nagai, Moeto

2017-09-01

This paper presents a nanofabrication technique based on the electrochemically assisted chemical dissolution of zinc oxide (ZnO) single crystals in water at room temperature using a catalytically active Pt-coated atomic force microscopy (AFM) probe. Fabricated grooves featured depths and widths of several tens and several hundreds of nanometers, respectively. The material removal rate of ZnO was dramatically improved by controlling the formation of hydrogen ions (H+) on the surface of the catalytic Pt-coated probe via oxidation of H2O molecules; this reaction can be enhanced by applying a cathodic potential to an additional Pt-wire working electrode in a three-electrode configuration. Consequently, ZnO can be dissolved chemically in water as a soluble Zn2+ species via a reaction with H+ species present in high concentrations in the immediate vicinity of the AFM tip apex.

Simulation-based Extraction of Key Material Parameters from Atomic Force Microscopy

NASA Astrophysics Data System (ADS)

Alsafi, Huseen; Peninngton, Gray

Models for the atomic force microscopy (AFM) tip and sample interaction contain numerous material parameters that are often poorly known. This is especially true when dealing with novel material systems or when imaging samples that are exposed to complicated interactions with the local environment. In this work we use Monte Carlo methods to extract sample material parameters from the experimental AFM analysis of a test sample. The parameterized theoretical model that we use is based on the Virtual Environment for Dynamic AFM (VEDA) [1]. The extracted material parameters are then compared with the accepted values for our test sample. Using this procedure, we suggest a method that can be used to successfully determine unknown material properties in novel and complicated material systems. We acknowledge Fisher Endowment Grant support from the Jess and Mildred Fisher College of Science and Mathematics,Towson University.

Joule heating effects on particle immobilization in insulator-based dielectrophoretic devices.

PubMed

Gallo-Villanueva, Roberto C; Sano, Michael B; Lapizco-Encinas, Blanca H; Davalos, Rafael V

2014-02-01

In this work, the temperature effects due to Joule heating obtained by application of a direct current electric potential were investigated for a microchannel with cylindrical insulating posts employed for insulator-based dielectrophoresis. The conductivity of the suspending medium, the local electric field, and the gradient of the squared electric field, which directly affect the magnitude of the dielectrophoretic force exerted on particles, were computationally simulated employing COMSOL Multiphysics. It was observed that a temperature gradient is formed along the microchannel, which redistributes the conductivity of the suspending medium leading to an increase of the dielectrophoretic force toward the inlet of the channel while decreasing toward the outlet. Experimental results are in good agreement with simulations on the particle-trapping zones anticipated. This study demonstrates the importance of considering Joule heating effects when designing insulator-based dielectrophoresis systems. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hansen, Gerrit; Stone, Dáithí

Impacts of recent regional changes in climate on natural and human systems are documented across the globe, yet studies explicitly linking these observations to anthropogenic forcing of the climate are scarce. Here in this work, we provide a systematic assessment of the role of anthropogenic climate change for the range of impacts of regional climate trends reported in the IPCC’s Fifth Assessment Report. We find that almost two-thirds of the impacts related to atmospheric and ocean temperature can be confidently attributed to anthropogenic forcing. In contrast, evidence connecting changes in precipitation and their respective impacts to human influence is stillmore » weak. Moreover, anthropogenic climate change has been a major influence for approximately three-quarters of the impacts observed on continental scales. Finally, hence the effects of anthropogenic emissions can now be discerned not only globally, but also at more regional and local scales for a variety of natural and human systems.« less

The Work, the Workplace, and the Work Force of Tomorrow.

ERIC Educational Resources Information Center

Allen, Claudia

1995-01-01

Ann McLaughlin, a former secretary of labor, discusses her views on the future of the workplace. She feels that to solve the impending problem of educational deficits among the work force, employers will begin their own educational programs, improving both employee loyalty and work force mobility. Includes predictions for future growth fields.…

Polar Amplification of Global Warming in Models Without Ice-Albedo Feedbacks

NASA Astrophysics Data System (ADS)

Alexeev, V. A.; Langen, P. L.

2004-12-01

Non-ice-albedo feedback mechanisms leading to polar amplification, as reported by Alexeev (2003), are explored in three aquaplanet climate model systems of different complexity. We analyze this pattern using three different "ghost forcing" experiments (Hansen et al, 1997). In the first one we uniformly add 4W/m2 to the oceanic mixed layer in order to roughly simulate a 2xCO2 forcing at the surface. The second forcing, of the same magnitude, is applied only within the tropics and the third forcing is applied only polewards of 30 degrees (north and south). It turns out that our systems' equilibrium responses are linear with respect to these forcings. Surprisingly, the response to the tropical-only forcing is essentially non-local with quite significant warming at higher latitudes. The response to the high-latitude-only forcing is more local and has higher amplitude near the poles. Our explanation of the polar amplification obtained in the uniform forcing experiment is therefore two-fold. Firstly, the tropics are much more difficult to warm because of the higher sensitivity of the surface budget to SST changes at higher temperatures. Secondly, any extra heat deposited in the tropics is not easily radiated to outer space because of the high opaqueness of the tropical atmosphere. The energy, most of which is latent, needs to be redistributed by transports to the extra-tropics. Consequently, the tropical "ghost forcing" results in an essentially non-local response, while the extra-tropical one yields a more localized response, because the energy in the atmosphere cannot propagate effectively equator-wards from high latitudes. The paper deals with these mechanisms in three climate model systems with no ice-albedo feedbacks - an EBM and two different GCMs - one with cloud feedbacks and the other with cloud feedbacks excluded. References. Alexeev, V.A., (2003) Sensitivity to CO2 doubling of an atmospheric GCM coupled to an oceanic mixed layer: a linear analysis. Climate Dynamics, 20: p.775-787. Hansen, J., Sato M, and R. Ruedy, (1997) Radiative forcing and climate response, JGR, 102, No. D6, 6831-6864.

Progress towards measurement of entanglement entropy dynamics in one-dimensional interacting systems in the presence of disorder

NASA Astrophysics Data System (ADS)

Lukin, Alexander; Tai, M. Eric; Rispoli, Matthew; Schittko, Robert; Menke, Tim; Kaufman, Adam; Greiner, Markus

2017-04-01

Many-body localized states appear at odds with thermalization as they preserve the memory of their initial state. This behavior has drawn significant theoretical and experimental attention in recent years. Real space localization has been observed on various platforms and under a number of experimental conditions, both with and without interactions. However, the characteristic logarithmic growth of entanglement entropy, which distinguishes the many-body localized state from the non-interacting Anderson localized state, has only been studied in numerics and has yet to be investigated experimentally. We are working towards the phenomenon of localization in one dimensional, interacting Bose-Hubbard system using a quantum gas microscope. With site-resolved addressing and readout, our microscope provides full control over the studied system, in particular it allows us to add disorder into our system using a Fourier plane hologram. This gives us access to both local observables, such as the occupation of individual lattice sites, as well as the entanglement entropy. I will present our progress towards measuring the dependence of the entanglement entropy grows on the disorder strength and interactions in our system. National Science Foundation, Gordon and Betty Moore Foundation's EPiQS Initiative, Air Force Office of Scientific Research MURI program, NSF Graduate Research Fellowship Program (MNR).

Collaborative Localization and Location Verification in WSNs

PubMed Central

Miao, Chunyu; Dai, Guoyong; Ying, Kezhen; Chen, Qingzhang

2015-01-01

Localization is one of the most important technologies in wireless sensor networks. A lightweight distributed node localization scheme is proposed by considering the limited computational capacity of WSNs. The proposed scheme introduces the virtual force model to determine the location by incremental refinement. Aiming at solving the drifting problem and malicious anchor problem, a location verification algorithm based on the virtual force mode is presented. In addition, an anchor promotion algorithm using the localization reliability model is proposed to re-locate the drifted nodes. Extended simulation experiments indicate that the localization algorithm has relatively high precision and the location verification algorithm has relatively high accuracy. The communication overhead of these algorithms is relative low, and the whole set of reliable localization methods is practical as well as comprehensive. PMID:25954948

Estimation of motion fields by non-linear registration for local lung motion analysis in 4D CT image data.

PubMed

Werner, René; Ehrhardt, Jan; Schmidt-Richberg, Alexander; Heiss, Anabell; Handels, Heinz

2010-11-01

Motivated by radiotherapy of lung cancer non- linear registration is applied to estimate 3D motion fields for local lung motion analysis in thoracic 4D CT images. Reliability of analysis results depends on the registration accuracy. Therefore, our study consists of two parts: optimization and evaluation of a non-linear registration scheme for motion field estimation, followed by a registration-based analysis of lung motion patterns. The study is based on 4D CT data of 17 patients. Different distance measures and force terms for thoracic CT registration are implemented and compared: sum of squared differences versus a force term related to Thirion's demons registration; masked versus unmasked force computation. The most accurate approach is applied to local lung motion analysis. Masked Thirion forces outperform the other force terms. The mean target registration error is 1.3 ± 0.2 mm, which is in the order of voxel size. Based on resulting motion fields and inter-patient normalization of inner lung coordinates and breathing depths a non-linear dependency between inner lung position and corresponding strength of motion is identified. The dependency is observed for all patients without or with only small tumors. Quantitative evaluation of the estimated motion fields indicates high spatial registration accuracy. It allows for reliable registration-based local lung motion analysis. The large amount of information encoded in the motion fields makes it possible to draw detailed conclusions, e.g., to identify the dependency of inner lung localization and motion. Our examinations illustrate the potential of registration-based motion analysis.

Evolution of Metastable Defects and Its Effect on the Electronic Properties of MoS2 Films.

PubMed

Precner, M; Polaković, T; Qiao, Qiao; Trainer, D J; Putilov, A V; Di Giorgio, C; Cone, I; Zhu, Y; Xi, X X; Iavarone, M; Karapetrov, G

2018-04-30

We report on structural and electronic properties of defects in chemical vapor-deposited monolayer and few-layer MoS 2 films. Scanning tunneling microscopy, Kelvin probe force microscopy, and transmission electron microscopy were used to obtain high resolution images and quantitative measurements of the local density of states, work function and nature of defects in MoS 2 films. We track the evolution of defects that are formed under heating and electron beam irradiation. We observe formation of metastable domains with different work function values after annealing the material in ultra-high vacuum to moderate temperatures. We attribute these metastable values of the work function to evolution of crystal defects forming during the annealing. The experiments show that sulfur vacancies formed after exposure to elevated temperatures diffuse, coalesce, and migrate bringing the system from a metastable to equilibrium ground state. The process could be thermally or e-beam activated with estimated energy barrier for sulfur vacancy migration of 0.6 eV in single unit cell MoS 2 . Even at equilibrium conditions, the work function and local density of states values are strongly affected near grain boundaries and edges. The results provide initial estimates of the thermal budgets available for reliable fabrication of MoS 2 -based integrated electronics and indicate the importance of defect control and layer passivation.

Locals Rule: Historical Lessons for Creating Local Defense Forces for Afghanistan and Beyond

DTIC Science & Technology

2012-01-01

defense forces in the so-called “ Banana Wars,” recalling “that as a 28 Quoted in Shulimson and Johnson, 1978, p. 38. 29 Both quoted in Shulimson...accepted with perfumed rice and flowers by Shia in the south. It was our presence there that created Hezbollah” (Norton, 2007, p. 33). 12 For more on

Importance of Force Decomposition for Local Stress Calculations in Biomembrane Molecular Simulations.

PubMed

Vanegas, Juan M; Torres-Sánchez, Alejandro; Arroyo, Marino

2014-02-11

Local stress fields are routinely computed from molecular dynamics trajectories to understand the structure and mechanical properties of lipid bilayers. These calculations can be systematically understood with the Irving-Kirkwood-Noll theory. In identifying the stress tensor, a crucial step is the decomposition of the forces on the particles into pairwise contributions. However, such a decomposition is not unique in general, leading to an ambiguity in the definition of the stress tensor, particularly for multibody potentials. Furthermore, a theoretical treatment of constraints in local stress calculations has been lacking. Here, we present a new implementation of local stress calculations that systematically treats constraints and considers a privileged decomposition, the central force decomposition, that leads to a symmetric stress tensor by construction. We focus on biomembranes, although the methodology presented here is widely applicable. Our results show that some unphysical behavior obtained with previous implementations (e.g. nonconstant normal stress profiles along an isotropic bilayer in equilibrium) is a consequence of an improper treatment of constraints. Furthermore, other valid force decompositions produce significantly different stress profiles, particularly in the presence of dihedral potentials. Our methodology reveals the striking effect of unsaturations on the bilayer mechanics, missed by previous stress calculation implementations.

Local vibration inhibits H-reflex but does not compromise manual dexterity and does not increase tremor.

PubMed

Budini, Francesco; Laudani, Luca; Bernardini, Sergio; Macaluso, Andrea

2017-10-01

The present work aimed at investigating the effects of local vibration on upper limb postural and kinetic tremor, on manual dexterity and on spinal reflex excitability. Previous studies have demonstrated a decrease in spinal reflex excitability and in force fluctuations in the lower limb but an increase in force fluctuation in the upper limbs. As hand steadiness is of vital importance in many daily-based tasks, and local vibration may also be applied in movement disorders, we decided to further explore this phenomenon. Ten healthy volunteers (26±3years) were tested for H reflex, postural and kinetic tremor and manual dexterity through a Purdue test. EMG was recorded from flexor carpi radialis (FCR) and extensor digitorum communis (EDC). Measurements were repeated at baseline, after a control period during which no vibration was delivered and after vibration. Intervention consisted in holding for two minutes a vibrating handle (frequency 75Hz, displacement∼7mm), control consisted in holding for two minutes the same handle powered off. Reflex excitability decreased after vibration whilst postural tremor and manual dexterity were not affected. Peak kinetic tremor frequency increased from baseline to control measurements (P=0.002). Co-activation EDC/FCR increased from control to vibration (P=0.021). These results show that two minutes local vibration lead to a decrease in spinal excitability, did not compromise manual dexterity and did not increase tremor; however, in contrast with expectations, tremor did not decrease. It is suggested that vibration activated several mechanisms with opposite effects, which resulted in a neutral outcome on postural and kinetic tremor. Copyright © 2017 Elsevier B.V. All rights reserved.

The Influence of Body Mass Index, Sex, & Muscle Activation on Pressure Distribution During Lateral Falls on the Hip.

PubMed

Pretty, Steven P; Martel, Daniel R; Laing, Andrew C

2017-12-01

Hip fracture incidence rates are influenced by body mass index (BMI) and sex, likely through mechanistic pathways that influence dynamics of the pelvis-femur system during fall-related impacts. The goal of this study was to extend our understanding of these impact dynamics by investigating the effects of BMI, sex, and local muscle activation on pressure distribution over the hip region during lateral impacts. Twenty participants underwent "pelvis-release experiments" (which simulate a lateral fall onto the hip), including muscle-'relaxed' and 'contracted' trials. Males and low-BMI individuals exhibited 44 and 55% greater peak pressure, as well as 66 and 56% lower peripheral hip force, compared to females and high-BMI individuals, respectively. Local muscle activation increased peak force by 10%, contact area by 17%, and peripheral hip force by 11% compared to relaxed trials. In summary, males and low-BMI individuals exhibited more concentrated loading over the greater trochanter. Muscle activation increased peak force, but this force was distributed over a larger area, preventing increased localized loading over the greater trochanter. These findings suggest potential value in incorporating sex, gender, and muscle activation-specific force distributions as inputs into computational tissue-level models, and have implications for the design of personalized protective devices including wearable hip protectors.

Developing a Community-Wide Initiative to Address Childhood Adversity and Toxic Stress: A Case Study of The Philadelphia ACE Task Force.

PubMed

Pachter, Lee M; Lieberman, Leslie; Bloom, Sandra L; Fein, Joel A

The Philadelphia ACE Task Force is a community based collaborative of health care providers, researchers, community-based organizations, funders, and public sector representatives. The mission of the task force is to provide a venue to address childhood adversity and its consequences in the Philadelphia metropolitan region. In this article we describe the origins and metamorphosis of the Philadelphia ACE Task Force, which initially was narrowly focused on screening for adverse childhood experiences (ACEs) in health care settings but expanded its focus to better represent a true community-based approach to sharing experiences with addressing childhood adversity in multiple sectors of the city and region. The task force has been successful in developing a research agenda and conducting research on ACEs in the urban context, and has identified foci of local activity in the areas of professional training and workforce development, community education, and local practical interventions around adversity, trauma, and resiliency. In this article we also address the lessons learned over the first 5 years of the task force's existence and offers recommendations for future efforts to build a local community-based ACEs collaborative. Copyright © 2017 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.

Factors associated with sex work involvement among transgender women in Jamaica: a cross-sectional study.

PubMed

Logie, Carmen H; Wang, Ying; Lacombe-Duncan, Ashley; Jones, Nicolette; Ahmed, Uzma; Levermore, Kandasi; Neil, Ava; Ellis, Tyrone; Bryan, Nicolette; Marshall, Annecka; Newman, Peter A

2017-04-06

Transgender women are disproportionately impacted by HIV. Transgender women involved in sex work may experience exacerbated violence, social exclusion, and HIV vulnerabilities, in comparison with non-sex work-involved transgender women. Scant research has investigated sex work among transgender women in the Caribbean, including Jamaica, where transgender women report pervasive violence. The study objective was to examine factors associated with sex work involvement among transgender women in Jamaica. In 2015, we implemented a cross-sectional survey using modified peer-driven recruitment with transgender women in Kingston and Ocho Rios, Jamaica, in collaboration with a local community-based AIDS service organization. We conducted multivariable logistic regression analyses to identify factors associated with paid sex and transactional sex. Exchanging oral, anal or vaginal sex for money only was categorized as paid sex. Exchanging sex for survival needs (food, accommodation, transportation), drugs or alcohol, or for money along with survival needs and/or drugs/alcohol, was categorized as transactional sex. Among 137 transgender women (mean age: 24.0 [SD: 4.5]), two-thirds reported living in the Kingston area. Overall, 25.2% reported being HIV-positive. Approximately half (n = 71; 51.82%) reported any sex work involvement, this included sex in exchange for: money (n = 64; 47.06%); survival needs (n = 27; 19.85%); and drugs/alcohol (n = 6; 4.41%). In multivariable analyses, paid sex and transactional sex were both associated with: intrapersonal (depression), interpersonal (lower social support, forced sex, childhood sexual abuse, intimate partner violence, multiple partners/polyamory), and structural (transgender stigma, unemployment) factors. Participants reporting transactional sex also reported increased odds of incarceration perceived to be due to transgender identity, forced sex, homelessness, and lower resilience, in comparison with participants reporting no sex work involvement. Findings reveal high HIV infection rates among transgender women in Jamaica. Sex work-involved participants experience social and structural drivers of HIV, including violence, stigma, and unemployment. Transgender women involved in transactional sex also experience high rates of incarceration, forced sex and homelessness in comparison with non-sex workers. Taken together, these findings suggest that social ecological factors elevate HIV exposure among sex work-involved transgender women in Jamaica. Findings can inform interventions to advance human rights and HIV prevention and care cascades with transgender women in Jamaica.

Factors associated with sex work involvement among transgender women in Jamaica: a cross-sectional study

PubMed Central

Logie, Carmen H; Wang, Ying; Lacombe-Duncan, Ashley; Jones, Nicolette; Ahmed, Uzma; Levermore, Kandasi; Neil, Ava; Ellis, Tyrone; Bryan, Nicolette; Marshall, Annecka; Newman, Peter A

2017-01-01

Abstract Introduction: Transgender women are disproportionately impacted by HIV. Transgender women involved in sex work may experience exacerbated violence, social exclusion, and HIV vulnerabilities, in comparison with non-sex work-involved transgender women. Scant research has investigated sex work among transgender women in the Caribbean, including Jamaica, where transgender women report pervasive violence. The study objective was to examine factors associated with sex work involvement among transgender women in Jamaica. Methods: In 2015, we implemented a cross-sectional survey using modified peer-driven recruitment with transgender women in Kingston and Ocho Rios, Jamaica, in collaboration with a local community-based AIDS service organization. We conducted multivariable logistic regression analyses to identify factors associated with paid sex and transactional sex. Exchanging oral, anal or vaginal sex for money only was categorized as paid sex. Exchanging sex for survival needs (food, accommodation, transportation), drugs or alcohol, or for money along with survival needs and/or drugs/alcohol, was categorized as transactional sex. Results: Among 137 transgender women (mean age: 24.0 [SD: 4.5]), two-thirds reported living in the Kingston area. Overall, 25.2% reported being HIV-positive. Approximately half (n = 71; 51.82%) reported any sex work involvement, this included sex in exchange for: money (n = 64; 47.06%); survival needs (n = 27; 19.85%); and drugs/alcohol (n = 6; 4.41%). In multivariable analyses, paid sex and transactional sex were both associated with: intrapersonal (depression), interpersonal (lower social support, forced sex, childhood sexual abuse, intimate partner violence, multiple partners/polyamory), and structural (transgender stigma, unemployment) factors. Participants reporting transactional sex also reported increased odds of incarceration perceived to be due to transgender identity, forced sex, homelessness, and lower resilience, in comparison with participants reporting no sex work involvement. Conclusions: Findings reveal high HIV infection rates among transgender women in Jamaica. Sex work-involved participants experience social and structural drivers of HIV, including violence, stigma, and unemployment. Transgender women involved in transactional sex also experience high rates of incarceration, forced sex and homelessness in comparison with non-sex workers. Taken together, these findings suggest that social ecological factors elevate HIV exposure among sex work-involved transgender women in Jamaica. Findings can inform interventions to advance human rights and HIV prevention and care cascades with transgender women in Jamaica. PMID:28406598

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reiche, D.; Dalvit, D. A. R.; Busch, K.

We investigate the influence of spatial dispersion on atom-surface quantum friction. We show that for atom-surface separations shorter than the carrier's mean free path within the material, the frictional force can be several orders of magnitude larger than that predicted by local optics. In addition, when taking into account spatial dispersion effects, we show that the commonly used local thermal equilibrium approximation underestimates by approximately 95% the drag force, obtained by employing the recently reported nonequilibrium fluctuation-dissipation relation for quantum friction. Unlike the treatment based on local optics, spatial dispersion in conjunction with corrections to local thermal equilibrium change notmore » only the magnitude but also the distance scaling of quantum friction.« less

32 CFR 643.122 - Reserve facilities-Air Force and Navy use.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Reserve facilities-Air Force and Navy use. 643... Force and Navy use. MACOM may approve local agreements with other Army, DOD, and Reserve elements... Force or Navy Reserve, or which involve a transfer of funds between services for other than minor...

48 CFR 223.570 - Drug-free work force.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Drug-free work force. 223.570 Section 223.570 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Drug-Free Workplace 223.570 Drug-free work force. ...

48 CFR 223.570 - Drug-free work force.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Drug-free work force. 223.570 Section 223.570 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Drug-Free Workplace 223.570 Drug-free work force. ...

48 CFR 223.570 - Drug-free work force.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Drug-free work force. 223.570 Section 223.570 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Drug-Free Workplace 223.570 Drug-free work force. ...

48 CFR 223.570 - Drug-free work force.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Drug-free work force. 223.570 Section 223.570 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Drug-Free Workplace 223.570 Drug-free work force. ...

48 CFR 223.570 - Drug-free work force.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Drug-free work force. 223.570 Section 223.570 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Drug-Free Workplace 223.570 Drug-free work force. ...

Nanoscale observation of local bound charges of patterned protein arrays by scanning force microscopy

NASA Astrophysics Data System (ADS)

Oh, Y. J.; Jo, W.; Kim, S.; Park, S.; Kim, Y. S.

2008-09-01

A protein patterned surface using micro-contact printing methods has been investigated by scanning force microscopy. Electrostatic force microscopy (EFM) was utilized for imaging the topography and detecting the electrical properties such as the local bound charge distribution of the patterned proteins. It was found that the patterned IgG proteins are arranged down to 1 µm, and the 90° rotation of patterned anti-IgG proteins was successfully undertaken. Through the estimation of the effective areas, it was possible to determine the local bound charges of patterned proteins which have opposite electrostatic force behaviors. Moreover, we studied the binding probability between IgG and anti-IgG in a 1 µm2 MIMIC system by topographic and electrostatic signals for applicable label-free detections. We showed that the patterned proteins can be used for immunoassay of proteins on the functional substrate, and that they can also be used for bioelectronics device application, indicating distinct advantages with regard to accuracy and a label-free detection.

Internal Aspects of the Skill Transfer of Manual Assembly Work

ERIC Educational Resources Information Center

Doyo, Daisuke

2009-01-01

In manual assembly work, parts are often assembled by applying force with a simple tool or by hand. A worker thus needs control the force he or she applies in working, as an appropriate level of force is requisite for minimizing work failures and improving efficiency. The object of this study is to clarify the relationship between the level of…

Employment in Perspective: Women in the Labor Force. Third Quarter 1988. Report 758.

ERIC Educational Resources Information Center

Bureau of Labor Statistics (DOL), Washington, DC.

The female share of the older work force has nearly doubled since 1950. In 1987, the 6.2 million women aged 55 and over in the labor force constituted 4 of every 10 older workers. Because young women today have a stronger work attachment than did their mothers and grandmothers, the female share of the older work force is likely to continue to…

Morphology and force probing of primary murine liver sinusoidal endothelial cells.

PubMed

Zapotoczny, B; Owczarczyk, K; Szafranska, K; Kus, E; Chlopicki, S; Szymonski, M

2017-07-01

Liver sinusoidal endothelial cells (LSECs) represent unique type of endothelial cells featured by their characteristic morphology, ie, lack of a basement membrane and presence of fenestrations-transmembrane pores acting as a dynamic filter between the vascular space and the liver parenchyma. Delicate structure of LSECs membrane combined with a submicron size of fenestrations hinders their visualization in live cells. In this work, we apply atomic force microscopy contact mode to characterize fenestrations in LSECs. We reveal the structure of fenestrations in live LSECs. Moreover, we show that the high-resolution imaging of fenestrations is possible for the glutaraldehyde-fixed LSECs. Finally, thorough information about the morphology of LSECs including great contrast in visualization of sieve plates and fenestrations is provided using Force Modulation mode. We show also the ability to precisely localize the cell nuclei in fixed LSECs. It can be helpful for more precise description of nanomechanical properties of cell nuclei using atomic force microscopy. Presented methodology combining high-quality imaging of fixed cells with an additional nanomechanical information of both live and fixed LSECs provides a unique approach to study LSECs morphology and nanomechanics that could foster understanding of the role of LSECs in maintaining liver homeostasis. Copyright © 2017 John Wiley & Sons, Ltd.

Distributed microscopic actuation analysis of deformable plate membrane mirrors

NASA Astrophysics Data System (ADS)

Lu, Yifan; Yue, Honghao; Deng, Zongquan; Tzou, Hornsen

2018-02-01

To further reduce the areal density of optical mirrors used in space telescopes and other space-borne optical structures, the concept of flexible membrane deformable mirror has been proposed. Because of their high flexibility, poor stiffness and low damping properties, environmental excitations such as orbital maneuver, path changing, and non-uniform heating may induce unexpected vibrations and thus reduce working performance. Therefore, active vibration control is essential for these membrane mirrors. In this paper, two different mirror models, i.e., the plate membrane model and pure membrane model, are studied respectively. In order to investigate the modal vibration characteristics of the mirror, a piezoelectric layer is fully laminated on its non-reflective side to serve as actuators. Dynamic equations of the mirror laminated with piezoelectric actuators are presented first. Then, the actuator induced modal control force is defined. When the actuator area shrinks to infinitesimal, the expressions of microscopic local modal control force and its two components are obtained to predict the spatial microscopic actuation behavior of the mirror. Different membrane pretension forces are also applied to reveal the tension effects on the actuation of the mirror. Analyses indicate that the spatial distribution of modal micro-control forces is exactly the same with the sensing signals distribution of the mirror, which provides crucial guidelines for optimal actuator placement of membrane deformable mirrors.

Transformation of body force localized near the surface of a half-space into equivalent surface stresses.

PubMed

Rouge, Clémence; Lhémery, Alain; Ségur, Damien

2013-10-01

An electromagnetic acoustic transducer (EMAT) or a laser used to generate elastic waves in a component is often described as a source of body force confined in a layer close to the surface. On the other hand, models for elastic wave radiation more efficiently handle sources described as distributions of surface stresses. Equivalent surface stresses can be obtained by integrating the body force with respect to depth. They are assumed to generate the same field as the one that would be generated by the body force. Such an integration scheme can be applied to Lorentz force for conventional EMAT configuration. When applied to magnetostrictive force generated by an EMAT in a ferromagnetic material, the same scheme fails, predicting a null stress. Transforming body force into equivalent surface stresses therefore, requires taking into account higher order terms of the force moments, the zeroth order being the simple force integration over the depth. In this paper, such a transformation is derived up to the second order, assuming that body forces are localized at depths shorter than the ultrasonic wavelength. Two formulations are obtained, each having some advantages depending on the application sought. They apply regardless of the nature of the force considered.

Tropically driven and externally forced patterns of Antarctic sea ice change: reconciling observed and modeled trends

NASA Astrophysics Data System (ADS)

Schneider, David P.; Deser, Clara

2018-06-01

Recent work suggests that natural variability has played a significant role in the increase of Antarctic sea ice extent during 1979-2013. The ice extent has responded strongly to atmospheric circulation changes, including a deepened Amundsen Sea Low (ASL), which in part has been driven by tropical variability. Nonetheless, this increase has occurred in the context of externally forced climate change, and it has been difficult to reconcile observed and modeled Antarctic sea ice trends. To understand observed-model disparities, this work defines the internally driven and radiatively forced patterns of Antarctic sea ice change and exposes potential model biases using results from two sets of historical experiments of a coupled climate model compared with observations. One ensemble is constrained only by external factors such as greenhouse gases and stratospheric ozone, while the other explicitly accounts for the influence of tropical variability by specifying observed SST anomalies in the eastern tropical Pacific. The latter experiment reproduces the deepening of the ASL, which drives an increase in regional ice extent due to enhanced ice motion and sea surface cooling. However, the overall sea ice trend in every ensemble member of both experiments is characterized by ice loss and is dominated by the forced pattern, as given by the ensemble-mean of the first experiment. This pervasive ice loss is associated with a strong warming of the ocean mixed layer, suggesting that the ocean model does not locally store or export anomalous heat efficiently enough to maintain a surface environment conducive to sea ice expansion. The pervasive upper-ocean warming, not seen in observations, likely reflects ocean mean-state biases.

Tropically driven and externally forced patterns of Antarctic sea ice change: reconciling observed and modeled trends

NASA Astrophysics Data System (ADS)

Schneider, David P.; Deser, Clara

2017-09-01

Recent work suggests that natural variability has played a significant role in the increase of Antarctic sea ice extent during 1979-2013. The ice extent has responded strongly to atmospheric circulation changes, including a deepened Amundsen Sea Low (ASL), which in part has been driven by tropical variability. Nonetheless, this increase has occurred in the context of externally forced climate change, and it has been difficult to reconcile observed and modeled Antarctic sea ice trends. To understand observed-model disparities, this work defines the internally driven and radiatively forced patterns of Antarctic sea ice change and exposes potential model biases using results from two sets of historical experiments of a coupled climate model compared with observations. One ensemble is constrained only by external factors such as greenhouse gases and stratospheric ozone, while the other explicitly accounts for the influence of tropical variability by specifying observed SST anomalies in the eastern tropical Pacific. The latter experiment reproduces the deepening of the ASL, which drives an increase in regional ice extent due to enhanced ice motion and sea surface cooling. However, the overall sea ice trend in every ensemble member of both experiments is characterized by ice loss and is dominated by the forced pattern, as given by the ensemble-mean of the first experiment. This pervasive ice loss is associated with a strong warming of the ocean mixed layer, suggesting that the ocean model does not locally store or export anomalous heat efficiently enough to maintain a surface environment conducive to sea ice expansion. The pervasive upper-ocean warming, not seen in observations, likely reflects ocean mean-state biases.

Analysis of 20 magnetic clouds at 1 AU during a solar minimum

NASA Astrophysics Data System (ADS)

Gulisano, A. M.; Dasso, S.; Mandrini, C. H.; Démoulin, P.

We study 20 magnetic clouds, observed in situ by the spacecraft Wind, at the Lagrangian point L1, from 22 August, 1995, to 7 November, 1997. In previous works, assuming a cylindrical symmetry for the local magnetic configuration and a satellite trajectory crossing the axis of the cloud, we obtained their orientations using a minimum variance analysis. In this work we compute the orientations and magnetic configurations using a non-linear simultaneous fit of the geometric and physical parameters for a linear force-free model, including the possibility of a not null impact parameter. We quantify global magnitudes such as the relative magnetic helicity per unit length and compare the values found with both methods (minimum variance and the simultaneous fit). FULL TEXT IN SPANISH

Towards a better understanding of tidal dissipation at corotation layers in differentially rotating stars and planets

NASA Astrophysics Data System (ADS)

Astoul, A.; Mathis, S.; Baruteau, C.; André, Q.

2017-12-01

Star-planet tidal interactions play a significant role in the dynamical evolution of close-in planetary systems. We investigate the propagation and dissipation of tidal inertial waves in a stellar/planetary convective region. We take into account a latitudinal differential rotation for the background flow, similar to what is observed in the envelope of low-mass stars like the Sun. Previous works have shown that differential rotation significantly alters the propagation and dissipation properties of inertial waves. In particular, when the Doppler-shifted tidal frequency vanishes in the fluid, a critical layer forms where tidal dissipation can be greatly enhanced. Our present work develops a local analytic model to better understand the propagation and dissipation properties of tidally forced inertial waves at critical layers.

14 CFR 151.51 - Performance of construction work: Sponsor force account.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Performance of construction work: Sponsor force account. 151.51 Section 151.51 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT... Development Projects § 151.51 Performance of construction work: Sponsor force account. (a) Before undertaking...

14 CFR 151.51 - Performance of construction work: Sponsor force account.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Performance of construction work: Sponsor force account. 151.51 Section 151.51 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT... Development Projects § 151.51 Performance of construction work: Sponsor force account. (a) Before undertaking...

14 CFR 151.51 - Performance of construction work: Sponsor force account.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Performance of construction work: Sponsor force account. 151.51 Section 151.51 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT... Development Projects § 151.51 Performance of construction work: Sponsor force account. (a) Before undertaking...

14 CFR 151.51 - Performance of construction work: Sponsor force account.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Performance of construction work: Sponsor force account. 151.51 Section 151.51 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT... Development Projects § 151.51 Performance of construction work: Sponsor force account. (a) Before undertaking...

14 CFR 151.51 - Performance of construction work: Sponsor force account.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Performance of construction work: Sponsor force account. 151.51 Section 151.51 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT... Development Projects § 151.51 Performance of construction work: Sponsor force account. (a) Before undertaking...

Honeywell's Working Parents Task Force. Final Report and Recommendations.

ERIC Educational Resources Information Center

Honeywell, Inc., Minneapolis, Minn.

This publication provides a summary of the Honeywell Working Parent Task Force's recommendations on how to solve problems experienced by working parents. The Task Force consisted of three committees: the Employment Practices Committee (EPC); the Parent Education Committee (PEC); and the Child Care Facilities Committee (CCFC). After examining a…

Workforce Education: Issues for the New Century.

ERIC Educational Resources Information Center

Pautler, Albert J., Jr.

This paper is intended to guide small groups of vocational educators in discussions regarding work force education issues for the next century. The following work force issues are suggested: the aging work force; vocational education's role in reforming K-12 education; distance education for technical education programs; the labor shortages…

78 FR 67132 - GPS Satellite Simulator Control Working Group Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-08

... DEPARTMENT OF DEFENSE Department of the Air Force GPS Satellite Simulator Control Working Group Meeting AGENCY: Space and Missile Systems Center, Global Positioning Systems (GPS) Directorate, Air Force... Control Working Group (SSCWG) meeting on 6 December 2013 from 0900-1300 PST at Los Angeles Air Force Base...

Multi-disciplinary optimization of aeroservoelastic systems

NASA Technical Reports Server (NTRS)

Karpel, Mardechay

1992-01-01

The purpose of the research project was to continue the development of new methods for efficient aeroservoelastic analysis and optimization. The main targets were as follows: to complete the development of analytical tools for the investigation of flutter with large stiffness changes; to continue the work on efficient continuous gust response and sensitivity derivatives; and to advance the techniques of calculating dynamic loads with control and unsteady aerodynamic effects. An efficient and highly accurate mathematical model for time-domain analysis of flutter during which large structural changes occur was developed in cooperation with Carol D. Wieseman of NASA LaRC. The model was based on the second-year work 'Modal Coordinates for Aeroelastic Analysis with Large Local Structural Variations'. The work on continuous gust response was completed. An abstract of the paper 'Continuous Gust Response and Sensitivity Derivatives Using State-Space Models' was submitted for presentation in the 33rd Israel Annual Conference on Aviation and Astronautics, Feb. 1993. The abstract is given in Appendix A. The work extends the optimization model to deal with continuous gust objectives in a way that facilitates their inclusion in the efficient multi-disciplinary optimization scheme. Currently under development is a work designed to extend the analysis and optimization capabilities to loads and stress considerations. The work is on aircraft dynamic loads in response to impulsive and non-impulsive excitation. The work extends the formulations of the mode-displacement and summation-of-forces methods to include modes with significant local distortions, and load modes. An abstract of the paper,'Structural Dynamic Loads in Response to Impulsive Excitation' is given in appendix B. Another work performed this year under the Grant was 'Size-Reduction Techniques for the Determination of Efficient Aeroservoelastic Models' given in Appendix C.

Microrheology of highly crosslinked microtubule networks is dominated by force-induced crosslinker unbinding

PubMed Central

Yang, Yali; Bai, Mo; Klug, William S.; Levine, Alex J.

2012-01-01

We determine the time- and force-dependent viscoelastic responses of reconstituted networks of microtubules that have been strongly crosslinked by biotin-streptavidin bonds. To measure the microscale viscoelasticity of such networks, we use a magnetic tweezers device to apply localized forces. At short time scales, the networks respond nonlinearly to applied force, with stiffening at small forces, followed by a reduction in the stiffening response at high forces, which we attribute to the force-induced unbinding of crosslinks. At long time scales, force-induced bond unbinding leads to local network rearrangement and significant bead creep. Interestingly, the network retains its elastic modulus even under conditions of significant plastic flow, suggesting that crosslinker breakage is balanced by the formation of new bonds. To better understand this effect, we developed a finite element model of such a stiff filament network with labile crosslinkers obeying force-dependent Bell model unbinding dynamics. The coexistence of dissipation, due to bond breakage, and the elastic recovery of the network is possible because each filament has many crosslinkers. Recovery can occur as long as a sufficient number of the original crosslinkers are preserved under the loading period. When these remaining original crosslinkers are broken, plastic flow results. PMID:23577042

Topometry optimization of sheet metal structures for crashworthiness design using hybrid cellular automata

NASA Astrophysics Data System (ADS)

Mozumder, Chandan K.

The objective in crashworthiness design is to generate plastically deformable energy absorbing structures which can satisfy the prescribed force-displacement (FD) response. The FD behavior determines the reaction force, displacement and the internal energy that the structure should withstand. However, attempts to include this requirement in structural optimization problems remain scarce. The existing commercial optimization tools utilize models under static loading conditions because of the complexities associated with dynamic/impact loading. Due to the complexity of a crash event and the consequent time required to numerically analyze the dynamic response of the structure, classical methods (i.e., gradient-based and direct) are not well developed to solve this undertaking. This work presents an approach under the framework of the hybrid cellular automaton (HCA) method to solve the above challenge. The HCA method has been successfully applied to nonlinear transient topology optimization for crashworthiness design. In this work, the HCA algorithm has been utilized to develop an efficient methodology for synthesizing shell-based sheet metal structures with optimal material thickness distribution under a dynamic loading event using topometry optimization. This method utilizes the cellular automata (CA) computing paradigm and nonlinear transient finite element analysis (FEA) via ls-dyna. In this method, a set field variables is driven to their target states by changing a convenient set of design variables (e.g., thickness). These rules operate locally in cells within a lattice that only know local conditions. The field variables associated with the cells are driven to a setpoint to obtain the desired structure. This methodology is used to design for structures with controlled energy absorption with specified buckling zones. The peak reaction force and the maximum displacement are also constrained to meet the desired safety level according to passenger safety regulations. Design for prescribed FD response by minimizing the error between the actual response and desired FD curve is implemented. With the use of HCA rules, manufacturability constraints (e.g., rolling) and structures which can be manufactured by special techniques, such as, tailor-welded blanks (TWB), have also been implemented. This methodology is applied to shock-absorbing structural components for passengers in a crashing vehicle. These results are compared to previous designs showing the benefits of the method introduced in this work.

Development of a Compact Captive Balloon and Its Level Supporting

NASA Astrophysics Data System (ADS)

Nakao, Tatsuya; Fujiwara, Kazuhito; Furukawa, Motoyasu; Hiroe, Tetsuyuki

Many kinds of observation techniques have been developed to obtain the properties of atmospheric conditions. The advanced observation techniques of the flow in relatively large scale are remote sensing by satellite facilities, long range observations by radar or Doppler Sodar, etc., while data from conventional climometers set at fixed places are merely limited information about local scale flow. Captive balloons are also available and feasible for the observation of local flows if their standing mechanics are robust against the strong wind and the motion of balloon are stable for all wind direction and the change of wind direction. In this paper, a compact captive balloon (about 2m diam.) for flow measurement is proposed and the preservation of balloon height level and the stabilization of its motion are challenged by using a kite. The relation between force balances acted on the balloon and the balloon height or position was estimated and confirmed in experiments. Although the lift force of single kite worked successfully, it is found that the performance of plural kites is less in the traction of balloon since the interaction of their tensions. The compact balloon supported by the kite enabled the over 300m floating by virtue of the small size causing only low air resistance.

Myosin II Dynamics during Embryo Morphogenesis

NASA Astrophysics Data System (ADS)

Kasza, Karen

2013-03-01

During embryonic morphogenesis, the myosin II motor protein generates forces that help to shape tissues, organs, and the overall body form. In one dramatic example in the Drosophila melanogaster embryo, the epithelial tissue that will give rise to the body of the adult animal elongates more than two-fold along the head-to-tail axis in less than an hour. This elongation is accomplished primarily through directional rearrangements of cells within the plane of the tissue. Just prior to elongation, polarized assemblies of myosin II accumulate perpendicular to the elongation axis. The contractile forces generated by myosin activity orient cell movements along a common axis, promoting local cell rearrangements that contribute to global tissue elongation. The molecular and mechanical mechanisms by which myosin drives this massive change in embryo shape are poorly understood. To investigate these mechanisms, we generated a collection of transgenic flies expressing variants of myosin II with altered motor function and regulation. We found that variants that are predicted to have increased myosin activity cause defects in tissue elongation. Using biophysical approaches, we found that these myosin variants also have decreased turnover dynamics within cells. To explore the mechanisms by which molecular-level myosin dynamics are translated into tissue-level elongation, we are using time-lapse confocal imaging to observe cell movements in embryos with altered myosin activity. We are utilizing computational approaches to quantify the dynamics and directionality of myosin localization and cell rearrangements. These studies will help elucidate how myosin-generated forces control cell movements within tissues. This work is in collaboration with J. Zallen at the Sloan-Kettering Institute.

Cell Protrusion and Retraction Driven by Fluctuations in Actin Polymerization: A Two-Dimensional Model

PubMed Central

Ryan, Gillian L.; Holz, Danielle; Yamashiro, Sawako; Taniguchi, Daisuke; Watanabe, Naoki; Vavylonis, Dimitrios

2017-01-01

Animal cells that spread onto a surface often rely on actin-rich lamellipodial extensions to execute protrusion. Many cell types recently adhered on a two-dimensional substrate exhibit protrusion and retraction of their lamellipodia, even though the cell is not translating. Traveling waves of protrusion have also been observed, similar to those observed in crawling cells. These regular patterns of protrusion and retraction allow quantitative analysis for comparison to mathematical models. The periodic fluctuations in leading edge position of XTC cells have been linked to excitable actin dynamics using a one-dimensional model of actin dynamics, as a function of arc-length along the cell. In this work we extend this earlier model of actin dynamics into two dimensions (along the arc-length and radial directions of the cell) and include a model membrane that protrudes and retracts in response to the changing number of free barbed ends of actin filaments near the membrane. We show that if the polymerization rate at the barbed ends changes in response to changes in their local concentration at the leading edge and/or the opposing force from the cell membrane, the model can reproduce the patterns of membrane protrusion and retraction seen in experiment. We investigate both Brownian ratchet and switch-like force-velocity relationships between the membrane load forces and actin polymerization rate. The switch-like polymerization dynamics recover the observed patterns of protrusion and retraction as well as the fluctuations in F-actin concentration profiles. The model generates predictions for the behavior of cells after local membrane tension perturbations. PMID:28752950

Regionalization of municipal solid waste management in Japan: balancing the proximity principle with economic efficiency.

PubMed

Okuda, Itaru; Thomson, Vivian E

2007-07-01

The proximity principle - disposing of waste close to its origin - has been a central value in municipal solid waste (MSW) management in Japan for the last 30 years and its widespread adoption has helped resolve numerous "Not in My Backyard" issues related to MSW management. However, MSW management costs have soared, in large part because of aggressive recycling efforts and because most MSW is incinerated in a country that has scarce landfill capacity. In addition, smaller, less sophisticated incinerators have been closed because of high dioxin emissions. Rising costs combined with the closure of smaller incinerators have shifted MSW management policy toward regionalization, which is the sharing of waste management facilities across municipalities. Despite the increased use of regionalized MSW facilities, the proximity principle remains the central value in Japanese MSW management. Municipal solid waste management has become increasingly regionalized in the United States, too, but different driving forces are at work in these two countries. The transition to regionalized MSW management in Japan results from strong governmental control at all levels, with the central government providing funds and policy direction and prefectures and municipalities being the primary implementing authorities. By contrast, market forces are a much stronger force with US MSW management, where local governments - with state government oversight - have primary responsibility for MSW management. We describe recent changes in Japan's MSW programs. We examine the connections between MSW facility regionalization, on the one hand, and, on the other hand, the proximity principle, coordination among local governments, central government control, and financing mechanisms.

A positional code and anisotropic forces control tissue remodeling in Drosophila

NASA Astrophysics Data System (ADS)

Zallen, Jennifer

A major challenge in developmental biology is to understand how tissue-scale changes in organism structure arise from events that occur on a cellular and molecular level. We are using cell biological, biophysical, and quantitative live-embryo imaging approaches to understand how genes encode the forces that shape tissues, and to identify the mechanisms that modulate cell behavior in response to local forces. In many animals, the elongated head-to-tail body axis is achieved by rapid and coordinated movements of hundreds of cells. We found that in the fruit fly, these cell movements are regulated by subcellular asymmetries in the localization of proteins that generate contractile and adhesive forces between cells. Asymmetries in the force-generating machinery are in turn controlled by a positional code of spatial information provided by an ancient family of Toll-related receptors that are widely used for pathogen recognition by the innate immune system. I will describe how this spatial system systematically orients local cell movements and collective rosette-like clusters in the Drosophila embryo. Rosettes have now also been shown to shape the body axis in chicks, frogs, and mice, demonstrating that rosette behaviors are a general mechanism linking cellular asymmetry to tissue reorganization.

Crisis Relocation Workshops for Transportation Industry Representatives

DTIC Science & Technology

1979-12-01

executive, two National Guard members, one Air Force transporta- _a ,tion representative, two Red Cross representatives, one school bus z coordinators...manaaers, local transitCD operator, and miiltary busingA authorityA Local Governa-ient 2 Fire chief, assistantI Air Force 3 Liaison Support D CPA :z...to attend the workshop. Majur trans- portation problems anticipated during crisis relocation include: 1. Transportation of carless residents; 2. The

Towards a Learning Workforce: A Policy Discussion Paper on Adult Learners at Work.

ERIC Educational Resources Information Center

Tuckett, Alan

There is widespread agreement in Great Britain that the work force must receive more skills training if the country is to be competitive in the future. Of special concern is the 70 percent of the work force who left school at the earliest possible opportunity, and the (overlapping) 70 percent of the work force who have not received training for a…

Combined effect of repetitive work and cold on muscle function and fatigue.

PubMed

Oksa, Juha; Ducharme, Michel B; Rintamäki, Hannu

2002-01-01

This study compared the effect of repetitive work in thermoneutral and cold conditions on forearm muscle electromyogram (EMG) and fatigue. We hypothesize that cold and repetitive work together cause higher EMG activity and fatigue than repetitive work only, thus creating a higher risk for overuse injuries. Eight men performed six 20-min work bouts at 25 degrees C (W-25) and at 5 degrees C while exposed to systemic (C-5) and local cooling (LC-5). The work was wrist flexion-extension exercise at 10% maximal voluntary contraction. The EMG activity of the forearm flexors and extensors was higher during C-5 (31 and 30%, respectively) and LC-5 (25 and 28%, respectively) than during W-25 (P < 0.05). On the basis of fatigue index (calculated from changes in maximal flexor force and flexor EMG activity), the fatigue in the forearm flexors at the end of W-25 was 15%. The corresponding values at the end of C-5 and LC-5 were 37% (P < 0.05 in relation to W-25) and 20%, respectively. Thus repetitive work in the cold causes higher EMG activity and fatigue than repetitive work in thermoneutral conditions.

Roles of production, consumption and trade in global and regional aerosol radiative forcing

NASA Astrophysics Data System (ADS)

Lin, J.; Tong, D.; Davis, S. J.; Ni, R.; Tan, X.; Pan, D.; Zhao, H.; Lu, Z.; Streets, D. G.; Feng, T.; Zhang, Q.; Yan, Y.; Hu, Y.; Li, J.; Liu, Z.; Jiang, X.; Geng, G.; He, K.; Huang, Y.; Guan, D.

2016-12-01

Anthropogenic aerosols exert strong radiative forcing on the climate system. Prevailing view regards aerosol radiative forcing as a result of emissions from regions' economic production, with China and other developing regions having the largest contributions to radiative forcing at present. However, economic production is driven by global demand for computation, and international trade allows for separation of regions consuming goods and services from regions where goods and related aerosol pollution are produced. It has recently been recognized that regions' consumption and trade have profoundly altered the spatial distribution of aerosol emissions and pollution. Building upon our previous work, this study quantifies for the first time the roles of trade and consumption in aerosol climate forcing attributed to different regions. We contrast the direct radiative forcing of aerosols related to regions' consumption of goods and services against the forcing due to emissions produced in each region. Aerosols assessed include black carbon, primary organic aerosol, and secondary inorganic aerosols including sulfate, nitrate and ammonium. We find that global aerosol radiative forcing due to emissions produced in East Asia is much stronger than the forcing related to goods and services ultimately consumed in that region because of its large net export of emissions-intensive goods. The opposite is true for net importers like Western Europe and North America: global radiative forcing related to consumption is much greater than the forcing due to emissions produced in these regions. Overall, trade is associated with a shift of radiative forcing from net importing to net exporting regions. Compared to greenhouse gases such as carbon dioxide, the short atmospheric lifetimes of aerosols cause large localized differences in radiative forcing. International efforts to reduce emissions in the exporting countries will help alleviate trade-related climate and health impacts of aerosols while lowering global emissions associated with global consumption. Ref: Lin et al., China's international trade and air pollution in the United States, PNAS, 2014 Lin et al., Global climate forcing of aerosols embodied in international trade, Nature Geoscience, 2016

An Advanced Actuator Line Method for Wind Energy Applications and Beyond

DOE Office of Scientific and Technical Information (OSTI.GOV)

Churchfield, Matthew J.; Schreck, Scott; Martinez-Tossas, Luis A.

The actuator line method to represent rotor aerodynamics within computational fluid dynamics has been in use for over a decade. This method applies a body force to the flow field along rotating lines corresponding to the individual rotor blades and employs tabular airfoil data to compute the force distribution. The actuator line method is attractive because compared to blade-resolved simulations, the required mesh is much simpler and the computational cost is lower. This work proposes a higher fidelity variant of the actuator line method meant to fill the space between current actuator line and blade-resolved simulations. It contains modifications inmore » two key areas. The first is that of freestream velocity vector estimation along the line, which is necessary to compute the lift and drag along the line using tabular airfoil data. Most current methods rely on point sampling in which the location of sampling is ambiguous. Here we test a velocity sampling method that uses a properly weighted integral over space, removing this ambiguity. The second area of improvement is the function used to project the one-dimensional actuator line force onto the three-dimensional fluid mesh as a body force. We propose and test a projection function that spreads the force over a region that looks something like a real blade with the hope that it will produce the blade local and near wake flow features with more accuracy and higher fidelity. Our goal is that between these two improvements, not only will the flow field predictions be enhanced, but also the spanwise loading will be made more accurate. We refer to this combination of improvements as the advanced actuator line method. We apply these improvements to two different wind turbine cases. Although there is a strong wind energy motivation in our work, there is no reason these advanced actuator line ideas cannot be used in other applications, such as helicopter rotors.« less

An Advanced Actuator Line Method for Wind Energy Applications and Beyond: Preprint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Churchfield, Matthew; Schreck, Scott; Martinez-Tossas, Luis A.

The actuator line method to represent rotor aerodynamics within computational fluid dynamics has been in use for over a decade. This method applies a body force to the flow field along rotating lines corresponding to the individual rotor blades and employs tabular airfoil data to compute the force distribution. The actuator line method is attractive because compared to blade-resolved simulations, the required mesh is much simpler and the computational cost is lower. This work proposes a higher fidelity variant of the actuator line method meant to fill the space between current actuator line and blade-resolved simulations. It contains modifications inmore » two key areas. The first is that of freestream velocity vector estimation along the line, which is necessary to compute the lift and drag along the line using tabular airfoil data. Most current methods rely on point sampling in which the location of sampling is ambiguous. Here we test a velocity sampling method that uses a properly weighted integral over space, removing this ambiguity. The second area of improvement is the function used to project the one-dimensional actuator line force onto the three-dimensional fluid mesh as a body force. We propose and test a projection function that spreads the force over a region that looks something like a real blade with the hope that it will produce the blade local and near wake flow features with more accuracy and higher fidelity. Our goal is that between these two improvements, not only will the flow field predictions be enhanced, but also the spanwise loading will be made more accurate. We refer to this combination of improvements as the advanced actuator line method. We apply these improvements to two different wind turbine cases. Although there is a strong wind energy motivation in our work, there is no reason these advanced actuator line ideas cannot be used in other applications, such as helicopter rotors.« less

Optogenetic control of RhoA reveals zyxin-mediated elasticity of stress fibres

NASA Astrophysics Data System (ADS)

Oakes, Patrick W.; Wagner, Elizabeth; Brand, Christoph A.; Probst, Dimitri; Linke, Marco; Schwarz, Ulrich S.; Glotzer, Michael; Gardel, Margaret L.

2017-06-01

Cytoskeletal mechanics regulates cell morphodynamics and many physiological processes. While contractility is known to be largely RhoA-dependent, the process by which localized biochemical signals are translated into cell-level responses is poorly understood. Here we combine optogenetic control of RhoA, live-cell imaging and traction force microscopy to investigate the dynamics of actomyosin-based force generation. Local activation of RhoA not only stimulates local recruitment of actin and myosin but also increased traction forces that rapidly propagate across the cell via stress fibres and drive increased actin flow. Surprisingly, this flow reverses direction when local RhoA activation stops. We identify zyxin as a regulator of stress fibre mechanics, as stress fibres are fluid-like without flow reversal in its absence. Using a physical model, we demonstrate that stress fibres behave elastic-like, even at timescales exceeding turnover of constituent proteins. Such molecular control of actin mechanics likely plays critical roles in regulating morphodynamic events.

Quantum Monte Carlo calculations of neutron matter with chiral three-body forces

DOE PAGES

Tews, I.; Gandolfi, Stefano; Gezerlis, A.; ...

2016-02-02

Chiral effective field theory (EFT) enables a systematic description of low-energy hadronic interactions with controlled theoretical uncertainties. For strongly interacting systems, quantum Monte Carlo (QMC) methods provide some of the most accurate solutions, but they require as input local potentials. We have recently constructed local chiral nucleon-nucleon (NN) interactions up to next-to-next-to-leading order (N 2LO). Chiral EFT naturally predicts consistent many-body forces. In this paper, we consider the leading chiral three-nucleon (3N) interactions in local form. These are included in auxiliary field diffusion Monte Carlo (AFDMC) simulations. We present results for the equation of state of neutron matter and formore » the energies and radii of neutron drops. Specifically, we study the regulator dependence at the Hartree-Fock level and in AFDMC and find that present local regulators lead to less repulsion from 3N forces compared to the usual nonlocal regulators.« less

Long-range dipolar order and dispersion forces in polar liquids

NASA Astrophysics Data System (ADS)

Besford, Quinn Alexander; Christofferson, Andrew Joseph; Liu, Maoyuan; Yarovsky, Irene

2017-11-01

Complex solvation phenomena, such as specific ion effects, occur in polar liquids. Interpretation of these effects in terms of structure and dispersion forces will lead to a greater understanding of solvation. Herein, using molecular dynamics, we probe the structure of polar liquids through specific dipolar pair correlation functions that contribute to the potential of mean force that is "felt" between thermally rotating dipole moments. It is shown that unique dipolar order exists at separations at least up to 20 Å for all liquids studied. When the structural order is compared with a dipolar dispersion force that arises from local co-operative enhancement of dipole moments, a strong agreement is found. Lifshitz theory of dispersion forces was compared with the structural order, where the theory is validated for all liquids that do not have significant local dipole correlations. For liquids that do have significant local dipole correlations, specifically liquid water, Lifshitz theory underestimates the dispersion force by a factor of 5-10, demonstrating that the force that leads to the increased structure in liquid water is missed by Lifshitz theory of van der Waals forces. We apply similar correlation functions to an ionic aqueous system, where long-range order between water's dipole moment and a single chloride ion is found to exist at 20 Å of separation, revealing a long-range perturbation of water's structure by an ion. Furthermore, we found that waters within the 1st, 2nd, and 3rd solvation shells of a chloride ion exhibit significantly enhanced dipolar interactions, particularly with waters at larger distances of separation. Our results provide a link between structures, dispersion forces, and specific ion effects, which may lead to a more robust understanding of solvation.

The impact of stabilizing forces on postsurgical recovery in ostomy patients.

PubMed

Nichols, Thom R; Riemer, Michael

2008-01-01

Patient recovery from life-altering surgery is a complex event requiring interactions among multiple factors that influence recovery. Two such factors are occupational stability and spouse/partner relationship stability. We surveyed persons who have undergone ostomy surgery. Subjects were recruited from the general population, without regard to geographic region or clinical setting. Participation in the study was voluntary; subjects had given prior permission to be contacted about survey-based research. Additional subjects were recruited from Web-based ostomy sites and local ostomy support group meetings. The survey instrument contains 113 items designed to investigate pre- and postsurgery aspects of the lives of those who have undergone ostomy surgery. Ostomates experiencing a postsurgery change in both occupation and work habits were significantly more likely to report a nonpositive life satisfaction score than those experiencing no postoperative change in occupation or work habit. Additionally, a stable spouse/life partner relationship emerged as predictive of positive life satisfaction scores. For those that were married prior to surgery and remained married after surgery, and in which there was no change in occupation or work habit, 95.7% reported a positive life satisfaction score. Multiple stabilizing forces exist that influence the recovery of a patient following life-altering surgery such as creation of a stoma. Stability in occupation and spouse/partner relationship positively influenced life satisfaction scores following ostomy surgery.

The Changing Work Force. Trends and Issues Alerts.

ERIC Educational Resources Information Center

Lankard, Bettina A.

Economic pressures, work force diversity, and advances in technology are changing the nature of work and organizational policy and management. A predicted decline in the annual growth in gross national product is expected to trigger a slowdown in the labor force, especially in occupations that employ workers with only a high school education.…

[Fact Sheets on Working Women].

ERIC Educational Resources Information Center

National Commission on Working Women, Washington, DC.

These four fact sheets address a number of issues relating to women in the work force. The first, "An Overview of Women in the Work Force," offers a look at the numbers of women in the labor force, the occupational categories represented by women workers, women in professional and nonprofessional occupations, and women in nontraditional…

America's Changing Work Force. Statistics in Brief.

ERIC Educational Resources Information Center

American Association of Retired Persons, Washington, DC.

This booklet provides information about the changing work force. It offers a profile of workers aged 45 and older, as well as likely changes in the work force of the future. Tables and graphs illustrate the following: profile of Americans aged 50 and older, by employment status; employment status of the civilian noninstitutional population by age…

Spatial dispersion in atom-surface quantum friction

DOE PAGES

Reiche, D.; Dalvit, D. A. R.; Busch, K.; ...

2017-04-15

We investigate the influence of spatial dispersion on atom-surface quantum friction. We show that for atom-surface separations shorter than the carrier's mean free path within the material, the frictional force can be several orders of magnitude larger than that predicted by local optics. In addition, when taking into account spatial dispersion effects, we show that the commonly used local thermal equilibrium approximation underestimates by approximately 95% the drag force, obtained by employing the recently reported nonequilibrium fluctuation-dissipation relation for quantum friction. Unlike the treatment based on local optics, spatial dispersion in conjunction with corrections to local thermal equilibrium change notmore » only the magnitude but also the distance scaling of quantum friction.« less

The impact of working technique on physical loads - an exposure profile among newspaper editors.

PubMed

Lindegård, A; Wahlström, J; Hagberg, M; Hansson, G-A; Jonsson, P; Wigaeus Tornqvist, E

2003-05-15

The aim of this study was to investigate the possible associations between working technique, sex, symptoms and level of physical load in VDU-work. A study group of 32 employees in the editing department of a daily newspaper answered a questionnaire, about physical working conditions and symptoms from the neck and the upper extremities. Muscular load, wrist positions and computer mouse forces were measured. Working technique was assessed from an observation protocol for computer work. In addition ratings of perceived exertion and overall comfort were collected. The results showed that subjects classified as having a good working technique worked with less muscular load in the forearm (extensor carpi ulnaris p=0.03) and in the trapezius muscle on the mouse operating side (p=0.02) compared to subjects classified as having a poor working technique. Moreover there were no differences in gap frequency (number of episodes when muscle activity is below 2.5% of a reference contraction) or muscular rest (total duration of gaps) between the two working technique groups. Women in this study used more force (mean force p=0.006, peak force p=0.02) expressed as % MVC than the men when operating the computer mouse. No major differences were shown in muscular load, wrist postures, perceived exertion or perceived comfort between men and women or between cases and symptom free subjects. In conclusion a good working technique was associated with reduced muscular load in the forearm muscles and in the trapezius muscle on the mouse operating side. Moreover women used more force (mean force and peak force) than men when operating the click button (left button) of the computer mouse.

Defining Conditions for the Use of Persistent Surveillance

DTIC Science & Technology

2009-12-01

as hard as the Air Force has worked the North Dakota and Ohio delegations,’ says Colonel Charles Bartlett, head of a special Air Force task force on...UAVs…While Richard Shelby , the Republican senator from Alabama, is concerned about the impact on Redstone Arsenal, which manages much of the Army’s...UAV work, Byron Dorgan, the North Dakota Democratic senator, wants to attract more work for Grand Forks Air Force base, partly to make up for the

Magnetic elements for switching magnetization magnetic force microscopy tips.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cambel, V.; Elias, P.; Gregusova, D.

2010-09-01

Using combination of micromagnetic calculations and magnetic force microscopy (MFM) imaging we find optimal parameters for novel magnetic tips suitable for switching magnetization MFM. Switching magnetization MFM is based on two-pass scanning atomic force microscopy with reversed tip magnetization between the scans. Within the technique the sum of the scanned data with reversed tip magnetization depicts local atomic forces, while their difference maps the local magnetic forces. Here we propose the design and calculate the magnetic properties of tips suitable for this scanning probe technique. We find that for best performance the spin-polarized tips must exhibit low magnetic moment, lowmore » switching fields, and single-domain state at remanence. The switching field of such tips is calculated and optimum shape of the Permalloy elements for the tips is found. We show excellent correspondence between calculated and experimental results for Py elements.« less

Systematic Breakdown of Amontons' Law of Friction for an Elastic Object Locally Obeying Amontons' Law

PubMed Central

Otsuki, Michio; Matsukawa, Hiroshi

2013-01-01

In many sliding systems consisting of solid object on a solid substrate under dry condition, the friction force does not depend on the apparent contact area and is proportional to the loading force. This behaviour is called Amontons' law and indicates that the friction coefficient, or the ratio of the friction force to the loading force, is constant. Here, however, using numerical and analytical methods, we show that Amontons' law breaks down systematically under certain conditions for an elastic object experiencing a friction force that locally obeys Amontons' law. The macroscopic static friction coefficient, which corresponds to the onset of bulk sliding of the object, decreases as pressure or system length increases. This decrease results from precursor slips before the onset of bulk sliding, and is consistent with the results of certain previous experiments. The mechanisms for these behaviours are clarified. These results will provide new insight into controlling friction. PMID:23545778

Growth Cone Biomechanics in Peripheral and Central Nervous System Neurons

NASA Astrophysics Data System (ADS)

Urbach, Jeffrey; Koch, Daniel; Rosoff, Will; Geller, Herbert

2012-02-01

The growth cone, a highly motile structure at the tip of an axon, integrates information about the local environment and modulates outgrowth and guidance, but little is known about effects of external mechanical cues and internal mechanical forces on growth-cone mediated guidance. We have investigated neurite outgrowth, traction forces and cytoskeletal substrate coupling on soft elastic substrates for dorsal root ganglion (DRG) neurons (from the peripheral nervous system) and hippocampal neurons (from the central) to see how the mechanics of the microenvironment affect different populations. We find that the biomechanics of DRG neurons are dramatically different from hippocampal, with DRG neurons displaying relatively large, steady traction forces and maximal outgrowth and forces on substrates of intermediate stiffness, while hippocampal neurons display weak, intermittent forces and limited dependence of outgrowth and forces on substrate stiffness. DRG growth cones have slower rates of retrograde actin flow and higher density of localized paxillin (a protein associated with substrate adhesion complexes) compared to hippocampal neurons, suggesting that the difference in force generation is due to stronger adhesions and therefore stronger substrate coupling in DRG growth cones.

Social connectedness and the transition from work to retirement.

PubMed

Lancee, Bram; Radl, Jonas

2012-07-01

Although there are numerous studies on the role of social connections in early working life, research that examines how social connectedness matters in the later stages of a career is scarce. The present study analyzes to what extent social connectedness affects the timing of the transition from work to retirement. We draw on data from the German Socioeconomic Panel Study (GSOEP) from the years 1985-2009 (N = 10,225), and we apply techniques of event history analysis. Social connectedness includes social gatherings with friends, relatives, and neighbors (informal participation) as well as engagement in voluntary and civic associations and local politics (formal participation). The findings demonstrate that social connectedness matters for the transition from work to retirement, but its impact depends on the type of participation. Whereas informal participation results in earlier retirement, formal participation delays labor force withdrawal. The findings suggest a trade-off between informal participation and work in later life, which leads people with frequent social contacts to opt for early retirement. By contrast, the fact that formal participation is associated with postponed retirement points to employment benefits of volunteering and civic engagement among older workers.

Statistics of work performed on a forced quantum oscillator.

PubMed

Talkner, Peter; Burada, P Sekhar; Hänggi, Peter

2008-07-01

Various aspects of the statistics of work performed by an external classical force on a quantum mechanical system are elucidated for a driven harmonic oscillator. In this special case two parameters are introduced that are sufficient to completely characterize the force protocol. Explicit results for the characteristic function of work and the corresponding probability distribution are provided and discussed for three different types of initial states of the oscillator: microcanonical, canonical, and coherent states. Depending on the choice of the initial state the probability distributions of the performed work may greatly differ. This result in particular also holds true for identical force protocols. General fluctuation and work theorems holding for microcanonical and canonical initial states are confirmed.

Mitigated-force carriage for high magnetic field environments

DOEpatents

Ludtka, Gerard M.; Ludtka, Gail M.; Wilgen, John B.; Murphy, Bart L.

2015-05-19

A carriage for high magnetic field environments includes a plurality of work-piece separators disposed in an operable relationship with a work-piece processing magnet having a magnetic field strength of at least 1 Tesla for supporting and separating a plurality of work-pieces by a preselected, essentially equal spacing, so that, as a first work-piece is inserted into the magnetic field, a second work-piece is simultaneously withdrawn from the magnetic field, so that an attractive magnetic force imparted on the first work-piece offsets a resistive magnetic force imparted on the second work-piece.

Influence of transverse-shear and large-deformation effects on the low-speed impact response of laminated composite plates

NASA Technical Reports Server (NTRS)

Ambur, Damodar R.; Starnes, James H., Jr.; Prasad, Chunchu B.

1993-01-01

An analytical procedure is presented for determining the transient response of simply supported, rectangular laminated composite plates subjected to impact loads from airgun-propelled or dropped-weight impactors. A first-order shear-deformation theory is included in the analysis to represent properly any local short-wave-length transient bending response. The impact force is modeled as a locally distributed load with a cosine-cosine distribution. A double Fourier series expansion and the Timoshenko small-increment method are used to determine the contact force, out-of-plane deflections, and in-plane strains and stresses at any plate location due to an impact force at any plate location. The results of experimental and analytical studies are compared for quasi-isotropic laminates. The results indicate that using the appropriate local force distribution for the locally loaded area and including transverse-shear-deformation effects in the laminated plate response analysis are important. The applicability of the present analytical procedure based on small deformation theory is investigated by comparing analytical and experimental results for combinations of quasi-isotropic laminate thicknesses and impact energy levels. The results of this study indicate that large-deformation effects influence the response of both 24- and 32-ply laminated plates, and that a geometrically nonlinear analysis is required for predicting the response accurately.

How Tidal Forces Cause Ocean Tides in the Equilibrium Theory

ERIC Educational Resources Information Center

Ng, Chiu-king

2015-01-01

We analyse why it is erroneous to think that a tidal bulge is formed by pulling the water surface directly up by a local vertical tidal force. In fact, ocean tides are caused by the global effect of the horizontal components of the tidal forces.

In-situ shear stress indicator using heated strain gages at the flow boundary

NASA Astrophysics Data System (ADS)

Yeh, Chi-An; Yang, Fuling

2011-11-01

This work borrows the concept of hot-wire anemometry and sketch a technique that uses local heat transfer to infer the flow field and the corresponding stress. Conventional strain gages were mounted at the flow solid boundary as the heat source and acrylic boundary was chosen for its low thermal conductivity ensuring heat accumulation when a gage is energized. The gage would now work in slightly overheated state and its self-heating leads to an additional thermal strain. When exposed to a flow field, heat is brought away by local forced convection, resulting in deviations in gage signal from that developed in quiescent liquid. We have developed a facility to achieve synchronous gage measurements at different locations on a solid boundary. Three steady flow motions were considered: circular Couette flow, rectilinear uniform flow, and rectilinear oscillating flow. Preliminary tests show the gage reading does respond to the imposed flow through thermal effects and greater deviation was measured in flows of higher shear strain rates. The correlation between the gage signals and the imposed flow field is further examined by theoretical analysis. We also introduced a second solid boundary to the vicinity of the gage in the two rectilinear flows. The gage readings demonstrate rises in its magnitudes indicating wall amplification effect on the local shear strain, agreeing to the drag augmentation by a second solid boundary reported in many multiphase flow literatures.

Bootstrapping of Life through Holonomy and Self-modification

NASA Astrophysics Data System (ADS)

Kazansky, Alexander B.

2010-11-01

Life on the Earth demonstrate not only adaptive, cognitive, particularly, anticipatory properties, but also active, transformative function to its local and global environment. As V. Vernadsky stated, life is a powerful geological force. Charles Darwin realized that too. In his last work [1] he proved, that earthworms through their vital activity in geological time scale are able to form and support contemporary structure of soil on the whole planet. Locally, through so-called process of niche construction [2] organisms virtually modifies abiotic and biotic factors of natural selection and thereby insert feedback loop in evolutionary process. Stigmergy [3] is one more form of indirect interaction of organisms via the environment by signs, left in local environment or just by performing working activity in swarms, leading to self-organization and coordination of actions in the process of refuges construction. In organization of life we can separate active, rigid, organism-like, autopoietic-like systems or less rigid, sympoietic, socio-biological type systems [4]. Nevertheless, all forms of life systems demonstrate so-called bootstrapping, or spontaneous process of self-organizing emergence. This process is feasible thanks to self-modification, and holonomy in their organization, or total reflexivity. Analysis of the role of indirect interactions in bootstrapping, made in this paper, is aimed at revealing relationships between concepts and making step to forming new systemic model of organization and evolution of special dual pair, biota and biosphere.

Experimental estimation of energy absorption during heel strike in human barefoot walking.

PubMed

Baines, Patricia M; Schwab, A L; van Soest, A J

2018-01-01

Metabolic energy expenditure during human gait is poorly understood. Mechanical energy loss during heel strike contributes to this energy expenditure. Previous work has estimated the energy absorption during heel strike as 0.8 J using an effective foot mass model. The aim of our study is to investigate the possibility of determining the energy absorption by more directly estimating the work done by the ground reaction force, the force-integral method. Concurrently another aim is to compare this method of direct determination of work to the method of an effective foot mass model. Participants of our experimental study were asked to walk barefoot at preferred speed. Ground reaction force and lower leg kinematics were collected at high sampling frequency (3000 Hz; 1295 Hz), with tight synchronization. The work done by the ground reaction force is 3.8 J, estimated by integrating this force over the foot-ankle deformation. The effective mass model is improved by dropping the assumption that foot-ankle deformation is maximal at the instant of the impact force peak. On theoretical grounds it is clear that in the presence of substantial damping that peak force and peak deformation do not occur simultaneously. The energy absorption results, due the vertical force only, corresponding to the force-integral method is similar to the results of the improved application of the effective mass model (2.7 J; 2.5 J). However the total work done by the ground reaction force calculated by the force-integral method is significantly higher than that of the vertical component alone. We conclude that direct estimation of the work done by the ground reaction force is possible and preferable over the use of the effective foot mass model. Assuming that energy absorbed is lost, the mechanical energy loss of heel strike is around 3.8 J for preferred walking speeds (≈ 1.3 m/s), which contributes to about 15-20% of the overall metabolic cost of transport.

Light-induced vibration in the hearing organ

PubMed Central

Ren, Tianying; He, Wenxuan; Li, Yizeng; Grosh, Karl; Fridberger, Anders

2014-01-01

The exceptional sensitivity of mammalian hearing organs is attributed to an active process, where force produced by sensory cells boost sound-induced vibrations, making soft sounds audible. This process is thought to be local, with each section of the hearing organ capable of amplifying sound-evoked movement, and nearly instantaneous, since amplification can work for sounds at frequencies up to 100 kHz in some species. To test these fundamental precepts, we developed a method for focally stimulating the living hearing organ with light. Light pulses caused intense and highly damped mechanical responses followed by traveling waves that developed with considerable delay. The delayed response was identical to movements evoked by click-like sounds. This shows that the active process is neither local nor instantaneous, but requires mechanical waves traveling from the cochlear base toward its apex. A physiologically-based mathematical model shows that such waves engage the active process, enhancing hearing sensitivity. PMID:25087606

Meshless Local Petrov-Galerkin Method for Bending Problems

NASA Technical Reports Server (NTRS)

Phillips, Dawn R.; Raju, Ivatury S.

2002-01-01

Recent literature shows extensive research work on meshless or element-free methods as alternatives to the versatile Finite Element Method. One such meshless method is the Meshless Local Petrov-Galerkin (MLPG) method. In this report, the method is developed for bending of beams - C1 problems. A generalized moving least squares (GMLS) interpolation is used to construct the trial functions, and spline and power weight functions are used as the test functions. The method is applied to problems for which exact solutions are available to evaluate its effectiveness. The accuracy of the method is demonstrated for problems with load discontinuities and continuous beam problems. A Petrov-Galerkin implementation of the method is shown to greatly reduce computational time and effort and is thus preferable over the previously developed Galerkin approach. The MLPG method for beam problems yields very accurate deflections and slopes and continuous moment and shear forces without the need for elaborate post-processing techniques.

Adjusting to military life--servicemen with problems coping and their outcomes.

PubMed

Cheok, C S; Ang, Y G; Chew, W M; Tan, H Y

2000-05-01

A small proportion of servicemen enlisting for compulsory National Service in Singapore experience problems adjusting to military life. This paper aims to profile the servicemen who experience such problems. There is a paucity of literature addressing this issue internationally and none published locally. Servicemen who were referred to the Psychological Medicine Branch of the Singapore Armed Forces within six months of enlistment were retrospectively studied. In the work year July 1995 to June 1996, 77 cases were seen. The main classes of diagnoses were stress-related disorders, anxiety, mood and psychotic disorders. The main stressor was problems adapting to the military environment. There were 10 cases of parasuicide, significantly less than US Army statistics. At Operationally Ready Date, 20.7% were able to hold a combat vocation, similar to the US Army situation. This paper hopes to document the local figures and act as a reference for evaluating future therapies and policies.

Viscous pulsational instability of the transonic region of isothermal geometrically thin accretion discs. I - Analytical results

NASA Astrophysics Data System (ADS)

Kato, Shoji; Honma, Fumio; Matsumoto, Ryoji

1988-03-01

Viscous instability of the transonic region of the conventional geometrically thin alpha-type accretion disks is examined analytically. For simplicity, isothermal disks and isothermal perturbations are assumed. It is found that when the value of alpha is larger than a critical value the disk is unstable against two types of perturbations. One is local propagating perturbations of inertial acoustic waves. Results suggest the possibility that unstable perturbations develop to overstable global oscillations which are restricted only in the innermost region of the disk. The other is standing growing perturbations localized just at the transonic point. The cause of these instabilities is that the azimuthal component of the Lagrangian velocity variation associated with the perturbations becomes in phase with the variation of the viscous stress force. Because of this phase matching work is done on perturbations, and they are amplified.

Portable haptic interface with omni-directional movement and force capability.

PubMed

Avizzano, Carlo Alberto; Satler, Massimo; Ruffaldi, Emanuele

2014-01-01

We describe the design of a new mobile haptic interface that employs wheels for force rendering. The interface, consisting of an omni-directional Killough type platform, provides 2DOF force feedback with different control modalities. The system autonomously performs sensor fusion for localization and force rendering. This paper explains the relevant choices concerning the functional aspects, the control design, the mechanical and electronic solution. Experimental results for force feedback characterization are reported.

Local diurnal wind-driven variabiity and upwelling in a small coastal embayment

NASA Astrophysics Data System (ADS)

Walter, R. K.; Reid, E. C.; Davis, K. A.; Armenta, K. J.; Merhoff, K.; Nidzieko, N.

2017-12-01

The oceanic response to high-frequency local diurnal wind forcing is examined in a small coastal embayment located along an understudied stretch of the central California coast. We show that local diurnal wind forcing is the dominant control on nearshore temperature variability and circulation patterns. A complex empirical orthogonal function (CEOF) analysis of velocities in San Luis Obispo Bay reveals that the first-mode CEOF amplitude time series, which accounts for 47.9% of the variance, is significantly coherent with the local wind signal at the diurnal frequency and aligns with periods of weak and strong wind forcing. The diurnal evolution of the hydrographic structure and circulation in the bay is examined using both individual events and composite-day averages. During the late afternoon, the local wind strengthens and results in a sheared flow with near-surface warm waters directed out of the bay and a compensating flow of colder waters into the bay over the bottom portion of the water column. This cold water intrusion into the bay causes isotherms to shoal toward the surface and delivers subthermocline waters to shallow reaches of the bay, representing a mechanism for small-scale upwelling. When the local winds relax, the warm water mass advects back into the bay in the form of a buoyant plume front. Local diurnal winds are expected to play an important role in nearshore dynamics and local upwelling in other small coastal embayments with important implications for various biological and ecological processes.

Local diurnal wind-driven variability and upwelling in a small coastal embayment

NASA Astrophysics Data System (ADS)

Walter, Ryan K.; Reid, Emma C.; Davis, Kristen A.; Armenta, Kevin J.; Merhoff, Kevin; Nidzieko, Nicholas J.

2017-02-01

The oceanic response to high-frequency local diurnal wind forcing is examined in a small coastal embayment located along an understudied stretch of the central California coast. We show that local diurnal wind forcing is the dominant control on nearshore temperature variability and circulation patterns. A complex empirical orthogonal function (CEOF) analysis of velocities in San Luis Obispo Bay reveals that the first-mode CEOF amplitude time series, which accounts for 47.9% of the variance, is significantly coherent with the local wind signal at the diurnal frequency and aligns with periods of weak and strong wind forcing. The diurnal evolution of the hydrographic structure and circulation in the bay is examined using both individual events and composite-day averages. During the late afternoon, the local wind strengthens and results in a sheared flow with near-surface warm waters directed out of the bay and a compensating flow of colder waters into the bay over the bottom portion of the water column. This cold water intrusion into the bay causes isotherms to shoal toward the surface and delivers subthermocline waters to shallow reaches of the bay, representing a mechanism for small-scale upwelling. When the local winds relax, the warm water mass advects back into the bay in the form of a buoyant plume front. Local diurnal winds are expected to play an important role in nearshore dynamics and local upwelling in other small coastal embayments with important implications for various biological and ecological processes.

Work and power outputs determined from pedalling and flywheel friction forces during brief maximal exertion on a cycle ergometer.

PubMed

Hibi, N; Fujinaga, H; Ishii, K

1996-01-01

Work and power outputs during short-term, maximal exertion on a friction loaded cycle ergometer are usually calculated from the friction force applied to the flywheel. The inertia of the flywheel is sometimes taken into consideration, but the effects of internal resistances and other factors have been ignored. The purpose of this study was to estimate their effects by comparing work or power output determined from the force exerted on the pedals (pedalling force) with work or power output determined from the friction force and the moment of inertia of the rotational parts. A group of 22 male college students accelerated a cycle ergometer as rapidly as possible for 3 s. The total work output determined from the pedalling force (TWp) was significantly greater than that calculated from the friction force and the moment of inertia (TWf). Power output determined from the pedalling force during each pedal stroke (SPp) was also significantly greater than that calculated from the friction force and the moment of inertia. Percentage difference (% diff), defined by % diff = ¿(TWp - TWf)/TWf¿ x 100, ranged from 16.8% to 49.3% with a mean value of 30.8 (SD 9.1)%. It was observed that % diff values were higher in subjects with greater TWp or greater maximal SPp. These results would indicate that internal resistances and other factors, such as the deformation of the chain and the vibrations of the entire system, may have significant effects on the measurements of work and power outputs. The effects appear to depend on the magnitudes of pedalling force and pedal velocity.

Work in America: Implications for Families. Hearing before the Select Committee on Children, Youth, and Families. House of Representatives, Ninety-Ninth Congress, Second Session.

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. House Select Committee on Children, Youth, and Families.

This hearing explored the value of work, and how changes in the economy and the composition of the work force have affected families. Witnesses (1) reported data on such topics as the kinds of jobs currently available, women's participation in the work force, unemployment, and labor force growth over the next decade; (2) argued that the economy is…

Anthropocene streams and base-level controls from historic dams in the unglaciated mid-Atlantic region, USA

USGS Publications Warehouse

Merritts, Dorothy; Walter, Robert; Rahnis, Michael; Hartranft, Jeff; Cox, Scott; Gellis, Allen; Potter, Noel; Hilgartner, William; Langland, Michael; Manion, Lauren; Lippincott, Caitlin; Siddiqui, Sauleh; Rehman, Zain; Scheid, Chris; Kratz, Laura; Shilling, Andrea; Jenschke, Matthew; Datin, Katherine; Cranmer, Elizabeth; Reed, Austin; Matuszewski, Derek; Voli, Mark; Ohlson, Erik; Neugebauer, Ali; Ahamed, Aakash; Neal, Conor; Winter, Allison; Becker, Steven

2011-01-01

Recently, widespread valley-bottom damming for water power was identified as a primary control on valley sedimentation in the mid-Atlantic US during the late seventeenth to early twentieth century. The timing of damming coincided with that of accelerated upland erosion during post-European settlement land-use change. In this paper, we examine the impact of local drops in base level on incision into historic reservoir sediment as thousands of ageing dams breach. Analysis of lidar and field data indicates that historic milldam building led to local base-level rises of 2-5 m (typical milldam height) and reduced valley slopes by half. Subsequent base-level fall with dam breaching led to an approximate doubling in slope, a significant base-level forcing. Case studies in forested, rural as well as agricultural and urban areas demonstrate that a breached dam can lead to stream incision, bank erosion and increased loads of suspended sediment, even with no change in land use. After dam breaching, key predictors of stream bank erosion include number of years since dam breach, proximity to a dam and dam height. One implication of this work is that conceptual models linking channel condition and sediment yield exclusively with modern upland land use are incomplete for valleys impacted by milldams. With no equivalent in the Holocene or late Pleistocene sedimentary record, modern incised stream-channel forms in the mid-Atlantic region represent a transient response to both base-level forcing and major changes in land use beginning centuries ago. Similar channel forms might also exist in other locales where historic milling was prevalent.

Mitigated-force carriage for high magnetic field environments

DOEpatents

Ludtka, Gerard M; Ludtka, Gail M; Wilgen, John B; Murphy, Bart L

2014-05-20

A carriage for high magnetic field environments includes a first work-piece holding means for holding a first work-piece, the first work-piece holding means being disposed in an operable relationship with a work-piece processing magnet having a magnetic field strength of at least 1 Tesla. The first work-piece holding means is further disposed in operable connection with a second work-piece holding means for holding a second work-piece so that, as the first work-piece is inserted into the magnetic field, the second work-piece is simultaneously withdrawn from the magnetic field, so that an attractive magnetic force imparted on the first work-piece offsets a resistive magnetic force imparted on the second work-piece.

Dynamics of molecular motors with finite processivity on heterogeneous tracks.

PubMed

Kafri, Yariv; Lubensky, David K; Nelson, David R

2005-04-01

The dynamics of molecular motors which occasionally detach from a heterogeneous track like DNA or RNA is considered. Motivated by recent single-molecule experiments, we study a simple model for a motor moving along a disordered track using chemical energy while an external force opposes its motion. The motors also have finite processivity, i.e., they can leave the track with a position-dependent rate. We show that the response of the system to disorder in the hopping-off rate depends on the value of the external force. For most values of the external force, strong disorder causes the motors which survive for long times on the track to be localized at preferred positions. However, near the stall force, localization occurs for any amount of disorder. To obtain these results, we study the complex eigenvalue spectrum of the time evolution operator. Existence of localized states near the top of the band implies a stretched exponential contribution to the decay of the survival probability. A similar spectral analysis also provides a very efficient method for studying the dynamics of motors with infinite processivity.

Profile of heating rate due to aerosols using lidar and skyradiometer in SKYNET Hefei site

NASA Astrophysics Data System (ADS)

Wang, Z.; Liu, D.; Xie, C.

2015-12-01

Atmospheric aerosols have a significant impact on climate due to their important role in modifying atmosphere energy budget. On global scale, the direct radiative forcing is estimated to be in the range of -0.9 to -0.1 Wm-2 for aerosols [1]. Yet, these estimates are subject to very large uncertainties because of uncertainties in spatial and temporal variations of aerosols. At local scales, as aerosol properties can vary spatially and temporally, radiative forcing due to aerosols can be also very different and it can exceed the global value by an order of magnitude. Hence, it is very important to investigate aerosol loading, properties, and radiative forcing due to them in detail on local regions of climate significance. Haze and dust events in Hefei, China are explored by Lidar and Skyradiometer. Aerosol optical properties including the AOD, SSA, AAE and size distribution are analysed by using the SKYRAD.PACK [2] and presented in this paper. Furthermore, the radiative forcing due to aerosols and the heating rate in the ATM are also calculated using SBDART model [3]. The results are shown that the vertical heating rate is tightly related to aerosol profile. References: 1. IPCC. 2007. Climate Change 2007: The Physical Science Basic. Contribution of Working Group I Contribution to the Intergovernmental Panel on Climate Change Fourth Assessment Report. Solomon S, Qing D H, Manning M, et al. eds., Cambridge University Press, Cambridge, United Kingdom and New York, N Y, USA. 2. Nakajima, T., G. Tonna, R. Rao, Y. Kaufman, and B. Holben, 1996: Use of sky brightness measurements from ground for remote sensing of particulate poly dispersions, Appl. Opt., 35, 2672-2686. 3. Ricchiazzi et al 1998. SBDART: a research and teaching software tool for plane-parallel radiative transfer in the Earth's atmosphere,Bulletin of the American Meteorological Society,79,2101-2114.

Stress Distribution in a Rigidly Clamped Composite Plate with Locally Curved Structures under Forced Vibration

NASA Astrophysics Data System (ADS)

Zamanov, A. D.

2001-09-01

A problem on the forced vibrations of a rectangular composite plate with locally curved structures is formulated using the exact three-dimensional equations of continuum mechanics and continuum theory. A technique for numerical solution of the problem is developed based on the semianalytic finite-element method. Numerical results are given for the stress distribution in the plate under forced vibrations. The results obtained are analyzed to study the effect of the curvature in the structure of the plate on the distribution of stress amplitudes. It is shown that the curvatures change significantly the stress pattern under either static or dynamic loading

Combustion Dynamics in Multi-Nozzle Combustors Operating on High-Hydrogen Fuels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Santavicca, Dom; Lieuwen, Tim

Actual gas turbine combustors for power generation applications employ multi-nozzle combustor configurations. Researchers at Penn State and Georgia Tech have extended previous work on the flame response in single-nozzle combustors to the more realistic case of multi-nozzle combustors. Research at Georgia Tech has shown that asymmetry of both the flow field and the acoustic forcing can have a significant effect on flame response and that such behavior is important in multi-flame configurations. As a result, the structure of the flame and its response to forcing is three-dimensional. Research at Penn State has led to the development of a three-dimensional chemiluminescencemore » flame imaging technique that can be used to characterize the unforced (steady) and forced (unsteady) flame structure of multi-nozzle combustors. Important aspects of the flame response in multi-nozzle combustors which are being studied include flame-flame and flame-wall interactions. Research at Penn State using the recently developed three-dimensional flame imaging technique has shown that spatial variations in local flame confinement must be accounted for to accurately predict global flame response in a multi-nozzle can combustor.« less

Topological mechanical metamaterials have perfectly directional bulk response

NASA Astrophysics Data System (ADS)

Rocklin, D. Zeb

The elastic response of typical materials to a local load is stress and strain in all directions. Here, we show contrariwise that mechanical frames with balanced numbers of constraints and degrees of freedom (the ''Maxwell'' condition) can experience stress and/or strain on only one side of a load. Kane and Lubensky showed, in a recent, seminal work, that such systems possess a topologically nontrivial phonon band structure corresponding to the electronic modes of topological insulators. Applying bulk-boundary correspondence, they demonstrated a signature physical consequence: the shifting of zero modes resultant from missing bonds from one edge to another. We now show that the same topological invariant governs such a system's bulk response: when bonds are swollen at one point the lattice does not distort evenly around it but instead only on one side dictated by the topological polarization. Similarly, when general forces are applied to a polarized lattice tension is induced in bonds only on one side of the applied force. Hence, topological polarization represents a sharp and robust way to direct force and motion and the response (Green's) function is a fundamental bulk signature of topological polarization. Bethe/KIC Fellowship, and the National Science Foundation Grant No. NSF DMR- 1308089.

Optimizing qPlus sensor assemblies for simultaneous scanning tunneling and noncontact atomic force microscopy operation based on finite element method analysis

DOE PAGES

Dagdeviren, Omur E.; Schwarz, Udo D.

2017-03-20

Quartz tuning forks that have a probe tip attached to the end of one of its prongs while the other prong is arrested to a holder (“qPlus” configuration) have gained considerable popularity in recent years for high-resolution atomic force microscopy imaging. The small size of the tuning forks and the complexity of the sensor architecture, however, often impede predictions on how variations in the execution of the individual assembly steps affect the performance of the completed sensor. Extending an earlier study that provided numerical analysis of qPlus-style setups without tips, this work quantifies the influence of tip attachment on themore » operational characteristics of the sensor. The results using finite element modeling show in particular that for setups that include a metallic tip that is connected via a separate wire to enable the simultaneous collection of local forces and tunneling currents, the exact realization of this wire connection has a major effect on sensor properties such as spring constant, quality factor, resonance frequency, and its deviation from an ideal vertical oscillation.« less

Optimizing qPlus sensor assemblies for simultaneous scanning tunneling and noncontact atomic force microscopy operation based on finite element method analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dagdeviren, Omur E.; Schwarz, Udo D.

Quartz tuning forks that have a probe tip attached to the end of one of its prongs while the other prong is arrested to a holder (“qPlus” configuration) have gained considerable popularity in recent years for high-resolution atomic force microscopy imaging. The small size of the tuning forks and the complexity of the sensor architecture, however, often impede predictions on how variations in the execution of the individual assembly steps affect the performance of the completed sensor. Extending an earlier study that provided numerical analysis of qPlus-style setups without tips, this work quantifies the influence of tip attachment on themore » operational characteristics of the sensor. The results using finite element modeling show in particular that for setups that include a metallic tip that is connected via a separate wire to enable the simultaneous collection of local forces and tunneling currents, the exact realization of this wire connection has a major effect on sensor properties such as spring constant, quality factor, resonance frequency, and its deviation from an ideal vertical oscillation.« less

Time-dependent and outflow boundary conditions for Dissipative Particle Dynamics

PubMed Central

Lei, Huan; Fedosov, Dmitry A.; Karniadakis, George Em

2011-01-01

We propose a simple method to impose both no-slip boundary conditions at fluid-wall interfaces and at outflow boundaries in fully developed regions for Dissipative Particle Dynamics (DPD) fluid systems. The procedure to enforce the no-slip condition is based on a velocity-dependent shear force, which is a generalized force to represent the presence of the solid-wall particles and to maintain locally thermodynamic consistency. We show that this method can be implemented in both steady and time-dependent fluid systems and compare the DPD results with the continuum limit (Navier-Stokes) results. We also develop a force-adaptive method to impose the outflow boundary conditions for fully developed flow with unspecified outflow velocity profile or pressure value. We study flows over the backward-facing step and in idealized arterial bifurcations using a combination of the two new boundary methods with different flow rates. Finally, we explore the applicability of the outflow method in time-dependent flow systems. The outflow boundary method works well for systems with Womersley number of O(1), i.e., when the pressure and flowrate at the outflow are approximately in-phase. PMID:21499548

Mechanical forces as information: an integrated approach to plant and animal development

PubMed Central

Hernández-Hernández, Valeria; Rueda, Denisse; Caballero, Lorena; Alvarez-Buylla, Elena R.; Benítez, Mariana

2014-01-01

Mechanical forces such as tension and compression act throughout growth and development of multicellular organisms. These forces not only affect the size and shape of the cells and tissues but are capable of modifying the expression of genes and the localization of molecular components within the cell, in the plasma membrane, and in the plant cell wall. The magnitude and direction of these physical forces change with cellular and tissue properties such as elasticity. Thus, mechanical forces and the mesoscopic fields that emerge from their local action constitute important sources of positional information. Moreover, physical and biochemical processes interact in non-linear ways during tissue and organ growth in plants and animals. In this review we discuss how such mechanical forces are generated, transmitted, and sensed in these two lineages of multicellular organisms to yield long-range positional information. In order to do so we first outline a potentially common basis for studying patterning and mechanosensing that relies on the structural principle of tensegrity, and discuss how tensegral structures might arise in plants and animals. We then provide some examples of morphogenesis in which mechanical forces appear to act as positional information during development, offering a possible explanation for ubiquitous processes, such as the formation of periodic structures. Such examples, we argue, can be interpreted in terms of tensegral phenomena. Finally, we discuss the hypothesis of mechanically isotropic points as a potentially generic mechanism for the localization and maintenance of stem-cell niches in multicellular organisms. This comparative approach aims to help uncovering generic mechanisms of morphogenesis and thus reach a better understanding of the evolution and development of multicellular phenotypes, focusing on the role of physical forces in these processes. PMID:24959170

Mechanical forces as information: an integrated approach to plant and animal development.

PubMed

Hernández-Hernández, Valeria; Rueda, Denisse; Caballero, Lorena; Alvarez-Buylla, Elena R; Benítez, Mariana

2014-01-01

Mechanical forces such as tension and compression act throughout growth and development of multicellular organisms. These forces not only affect the size and shape of the cells and tissues but are capable of modifying the expression of genes and the localization of molecular components within the cell, in the plasma membrane, and in the plant cell wall. The magnitude and direction of these physical forces change with cellular and tissue properties such as elasticity. Thus, mechanical forces and the mesoscopic fields that emerge from their local action constitute important sources of positional information. Moreover, physical and biochemical processes interact in non-linear ways during tissue and organ growth in plants and animals. In this review we discuss how such mechanical forces are generated, transmitted, and sensed in these two lineages of multicellular organisms to yield long-range positional information. In order to do so we first outline a potentially common basis for studying patterning and mechanosensing that relies on the structural principle of tensegrity, and discuss how tensegral structures might arise in plants and animals. We then provide some examples of morphogenesis in which mechanical forces appear to act as positional information during development, offering a possible explanation for ubiquitous processes, such as the formation of periodic structures. Such examples, we argue, can be interpreted in terms of tensegral phenomena. Finally, we discuss the hypothesis of mechanically isotropic points as a potentially generic mechanism for the localization and maintenance of stem-cell niches in multicellular organisms. This comparative approach aims to help uncovering generic mechanisms of morphogenesis and thus reach a better understanding of the evolution and development of multicellular phenotypes, focusing on the role of physical forces in these processes.

Labor Force

ERIC Educational Resources Information Center

Occupational Outlook Quarterly, 2012

2012-01-01

The labor force is the number of people ages 16 or older who are either working or looking for work. It does not include active-duty military personnel or the institutionalized population, such as prison inmates. Determining the size of the labor force is a way of determining how big the economy can get. The size of the labor force depends on two…

Flextime: A Modified Work Force Scheduling Technique for Selected Headquarters Air Force Logistics Command Organizations.

ERIC Educational Resources Information Center

Kimzey, Reed T.; Prince, Samuel M. O.

The thesis discusses the advantages and disadvantages of one work force scheduling technique--flextime. The authors were interested in determining if a flextime schedule could be put into effect in a governmental organization such as Headquarters Air Force Logistics Command (AFLC). The study objectives were to determine the feasibility,…

An Augmented Reality-Based Approach for Surgical Telementoring in Austere Environments.

PubMed

Andersen, Dan; Popescu, Voicu; Cabrera, Maria Eugenia; Shanghavi, Aditya; Mullis, Brian; Marley, Sherri; Gomez, Gerardo; Wachs, Juan P

2017-03-01

Telementoring can improve treatment of combat trauma injuries by connecting remote experienced surgeons with local less-experienced surgeons in an austere environment. Current surgical telementoring systems force the local surgeon to regularly shift focus away from the operating field to receive expert guidance, which can lead to surgery delays or even errors. The System for Telementoring with Augmented Reality (STAR) integrates expert-created annotations directly into the local surgeon's field of view. The local surgeon views the operating field by looking at a tablet display suspended between the patient and the surgeon that captures video of the surgical field. The remote surgeon remotely adds graphical annotations to the video. The annotations are sent back and displayed to the local surgeon while being automatically anchored to the operating field elements they describe. A technical evaluation demonstrates that STAR robustly anchors annotations despite tablet repositioning and occlusions. In a user study, participants used either STAR or a conventional telementoring system to precisely mark locations on a surgical simulator under a remote surgeon's guidance. Participants who used STAR completed the task with fewer focus shifts and with greater accuracy. The STAR reduces the local surgeon's need to shift attention during surgery, allowing him or her to continuously work while looking "through" the tablet screen. Reprint & Copyright © 2017 Association of Military Surgeons of the U.S.

In-Situ-measurement of restraining forces during forming of rectangular cups

NASA Astrophysics Data System (ADS)

Singer, M.; Liewald, M.

2016-11-01

This contribution introduces a new method for evaluating the restraining forces during forming of rectangular cups with the goal of eliminating the disadvantages of the currently used scientifically established measurement procedures. With this method forming forces are measured indirectly by the elastic deformation of die structure caused by locally varying tribological system. Therefore, two sensors were integrated into the punch, which measure the restraining forces during the forming process. Furthermore, it was possible to evaluate the effects of different lubricants showing the time dependent trend as a function of stroke during the forming of the materials DP600 and DC04. A main advantage of this testing method is to get real friction corresponding data out of the physical deep drawing process as well as the measurement of real acting restraining forces at different areas of the deep drawing part by one single test. Measurement results gained by both sensors have been integrated into LS-Dyna simulation in which the coefficient of friction was regarded as a function of time. The simulated and deep drawn parts afterwards are analysed and compared to specific areas with regard to locally measured thickness of part. Results show an improvement of simulation quality when using locally varying, time dependent coefficients of friction compared to commonly used constant values.

The health education of folk midwives: the Serviço Especial de Saúde Pública and mother-child assistance (1940-1960).

PubMed

Silva, Tânia Maria de Almeida; Ferreira, Luiz Otávio

2011-12-01

The article addresses an endeavor by Serviço Especial de Saúde Pública (Sesp) to train folk midwives who worked in rural communities and to exercise control over these women's activities. The task was entrusted to the agency's prenatal and child hygiene programs, established between the 1940s and 1960s. The agency believed this training and control initiative would be of major importance in helping ensure the success of its project to establish local sanitary services offering mother-child assistance. The goal of working directly with the folk midwives was not only to force them to employ strict hygiene standards when delivering and caring for newborns but especially to use their influence and prestige within these communities to convince the general population to adopt good health practices.

On the Ground in Afghanistan: Counterinsurgency in Practice

DTIC Science & Technology

2012-01-01

without earning the enmity of rival factions. For Coalition forces, the political fault lines are not clear, and there is constant danger of getting drawn...Province, rival factions tried constantly to use their access to Coalition troops as leverage against their local enemies. U.S. forces had allied with...learned that it was important to maintain a light footprint in order to gain access to the population; otherwise, a team’s actions could threaten local

Instability of a Supersonic Boundary-Layer with Localized Roughness

NASA Technical Reports Server (NTRS)

Marxen, Olaf; Iaccarino, Gianluca; Shaqfeh, Eric S. G.

2010-01-01

A localized 3-D roughness causes boundary-layer separation and (weak) shocks. Most importantly, streamwise vortices occur which induce streamwise (low U, high T) streaks. Immersed boundary method (volume force) suitable to represent roughness element in DNS. Favorable comparison between bi-global stability theory and DNS for a "y-mode" Outlook: Understand the flow physics (investigate "z-modes" in DNS through sinuous spanwise forcing, study origin of the beat in DNS).

Band Excitation Kelvin probe force microscopy utilizing photothermal excitation

DOE PAGES

Collins, Liam; Jesse, Stephen; Balke, Nina; ...

2015-03-13

A multifrequency open loop Kelvin probe force microscopy (KPFM) approach utilizing photothermal as opposed to electrical excitation is developed. Photothermal band excitation (PthBE)-KPFM is implemented here in a grid mode on a model test sample comprising a metal-insulator junction with local charge-patterned regions. Unlike the previously described open loop BE-KPFM, which relies on capacitive actuation of the cantilever, photothermal actuation is shown to be highly sensitive to the electrostatic force gradient even at biases close to the contact potential difference (CPD). PthBE-KPFM is further shown to provide a more localized measurement of true CPD in comparison to the gold standardmore » ambient KPFM approach, amplitude modulated KPFM. In conclusion, PthBE-KPFM data contain information relating to local dielectric properties and electronic dissipation between tip and sample unattainable using conventional single frequency KPFM approaches.« less

Damage identification of supporting structures with a moving sensory system

NASA Astrophysics Data System (ADS)

Zhu, X. Q.; Law, S. S.; Huang, L.; Zhu, S. Y.

2018-02-01

An innovative approach to identify local anomalies in a structural beam bridge with an instrumented vehicle moving as a sensory system across the bridge. Accelerations at both the axle and vehicle body are measured from which vehicle-bridge interaction force on the structure is determined. Local anomalies of the structure are estimated from this interaction force with the Newton's iterative method basing on the homotopy continuation method. Numerical results with the vehicle moving over simply supported or continuous beams show that the acceleration responses from the vehicle or the bridge structure are less sensitive to the local damages than the interaction force between the wheel and the structure. Effects of different movement patterns and moving speed of the vehicle are investigated, and the effect of measurement noise on the identified results is discussed. A heavier or slower vehicle has been shown to be less sensitive to measurement noise giving more accurate results.

Stabilization Operations Through Military Capacity Building-Integration Between Danish Conventional Forces and Special Operations Forces

DTIC Science & Technology

2016-12-01

Svendsen 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School Monterey, CA 93943-5000 8. PERFORMING ORGANIZATION REPORT...operations forces should be fully integrated across doctrine, organization , and technology, and predominantly advise, mentor, and train local forces. With...stability operations. This capstone makes additional recommendations related to doctrine, organization , and technology, as well as education and

Comparing the Values Hierarchy of the Kentucky Department of Education's Character/Values Task Force. Comparing a Character/Values Task Force to a National Sample.

ERIC Educational Resources Information Center

Butler, Fonda P.

In March 1989, the Kentucky Department of Education assembled a task force to make recommendations regarding the issue of teaching values and character in public schools in Kentucky. The 23-member task force represented educators, parents, the legislature, state and local school boards, law enforcement agencies, higher education, Catholic…

Using the Weak-Temperature Gradient Approximation to Evaluate Parameterizations: An Example of the Transition From Suppressed to Active Convection

NASA Astrophysics Data System (ADS)

Daleu, C. L.; Plant, R. S.; Woolnough, S. J.

2017-10-01

Two single-column models are fully coupled via the weak-temperature gradient approach. The coupled-SCM is used to simulate the transition from suppressed to active convection under the influence of an interactive large-scale circulation. The sensitivity of this transition to the value of mixing entrainment within the convective parameterization is explored. The results from these simulations are compared with those from equivalent simulations using coupled cloud-resolving models. Coupled-column simulations over nonuniform surface forcing are used to initialize the simulations of the transition, in which the column with suppressed convection is forced to undergo a transition to active convection by changing the local and/or remote surface forcings. The direct contributions from the changes in surface forcing are to induce a weakening of the large-scale circulation which systematically modulates the transition. In the SCM, the contributions from the large-scale circulation are dominated by the heating effects, while in the CRM the heating and moistening effects are about equally divided. A transition time is defined as the time when the rain rate in the dry column is halfway to the value at equilibrium after the transition. For the control value of entrainment, the order of the transition times is identical to that obtained in the CRM, but the transition times are markedly faster. The locally forced transition is strongly delayed by a higher entrainment. A consequence is that for a 50% higher entrainment the transition times are reordered. The remotely forced transition remains fast while the locally forced transition becomes slow, compared to the CRM.

Composition, Architecture, and Functional Implications of the Connective Tissue Network of the Extraocular Muscles

PubMed Central

McLoon, Linda K.; Vicente, André; Fitzpatrick, Krysta R.; Lindström, Mona

2018-01-01

Purpose We examined the pattern and extent of connective tissue distribution in the extraocular muscles (EOMs) and determined the ability of the interconnected connective tissues to disseminate force laterally. Methods Human EOMs were examined for collagens I, III, IV, and VI; fibronectin; laminin; and elastin using immunohistochemistry. Connective tissue distribution was examined with scanning electron microscopy. Rabbit EOMs were examined for levels of force transmission longitudinally and transversely using in vitro force assessment. Results Collagens I, III, and VI localized to the endomysium, perimysium, and epimysium. Collagen IV, fibronectin, and laminin localized to the basal lamina surrounding all myofibers. All collagens localized similarly in the orbital and global layers throughout the muscle length. Elastin had the most irregular pattern and ran longitudinally and circumferentially throughout the length of all EOMs. Scanning electron microscopy showed these elements to be extensively interconnected, from endomysium through the perimysium to the epimysium surrounding the whole muscle. In vitro physiology demonstrated force generation in the lateral dimension, presumably through myofascial transmission, which was always proportional to the force generated in the longitudinally oriented muscles. Conclusions A striking connective tissue matrix interconnects all the myofibers and extends, via perimysial connections, to the epimysium. These interconnections are significant and allow measurable force transmission laterally as well as longitudinally, suggesting that they may contribute to the nonlinear force summation seen in motor unit recording studies. This provides strong evidence that separate compartmental movements are unlikely as no region is independent of the rest of the muscle. PMID:29346490

Clique-Based Neural Associative Memories with Local Coding and Precoding.

PubMed

Mofrad, Asieh Abolpour; Parker, Matthew G; Ferdosi, Zahra; Tadayon, Mohammad H

2016-08-01

Techniques from coding theory are able to improve the efficiency of neuroinspired and neural associative memories by forcing some construction and constraints on the network. In this letter, the approach is to embed coding techniques into neural associative memory in order to increase their performance in the presence of partial erasures. The motivation comes from recent work by Gripon, Berrou, and coauthors, which revisited Willshaw networks and presented a neural network with interacting neurons that partitioned into clusters. The model introduced stores patterns as small-size cliques that can be retrieved in spite of partial error. We focus on improving the success of retrieval by applying two techniques: doing a local coding in each cluster and then applying a precoding step. We use a slightly different decoding scheme, which is appropriate for partial erasures and converges faster. Although the ideas of local coding and precoding are not new, the way we apply them is different. Simulations show an increase in the pattern retrieval capacity for both techniques. Moreover, we use self-dual additive codes over field [Formula: see text], which have very interesting properties and a simple-graph representation.

Inferring coarse-grain histone-DNA interaction potentials from high-resolution structures of the nucleosome

NASA Astrophysics Data System (ADS)

Meyer, Sam; Everaers, Ralf

2015-02-01

The histone-DNA interaction in the nucleosome is a fundamental mechanism of genomic compaction and regulation, which remains largely unknown despite increasing structural knowledge of the complex. In this paper, we propose a framework for the extraction of a nanoscale histone-DNA force-field from a collection of high-resolution structures, which may be adapted to a larger class of protein-DNA complexes. We applied the procedure to a large crystallographic database extended by snapshots from molecular dynamics simulations. The comparison of the structural models first shows that, at histone-DNA contact sites, the DNA base-pairs are shifted outwards locally, consistent with locally repulsive forces exerted by the histones. The second step shows that the various force profiles of the structures under analysis derive locally from a unique, sequence-independent, quadratic repulsive force-field, while the sequence preferences are entirely due to internal DNA mechanics. We have thus obtained the first knowledge-derived nanoscale interaction potential for histone-DNA in the nucleosome. The conformations obtained by relaxation of nucleosomal DNA with high-affinity sequences in this potential accurately reproduce the experimental values of binding preferences. Finally we address the more generic binding mechanisms relevant to the 80% genomic sequences incorporated in nucleosomes, by computing the conformation of nucleosomal DNA with sequence-averaged properties. This conformation differs from those found in crystals, and the analysis suggests that repulsive histone forces are related to local stretch tension in nucleosomal DNA, mostly between adjacent contact points. This tension could play a role in the stability of the complex.

Women of Hispanic Origin in the Labor Force. Facts on Working Women No. 89-1 = La mujer de origen hispano en la fuerza laboral. Facts on Working Women Num. 89-1S.

ERIC Educational Resources Information Center

Women's Bureau (DOL), Washington, DC.

Data on Hispanic women in the labor force between 1978 and 1988 show the following: (1) 6.5 percent of the women in the work force in 1988 were of Hispanic origin (3.6 million); (2) the median age of Hispanic women was 26.1 years, 2-5 years younger than Black or White women; (3) 66 percent of Hispanic women participate in the labor force, a higher…

Helical wire stress analysis of unbonded flexible riser under irregular response

NASA Astrophysics Data System (ADS)

Wang, Kunpeng; Ji, Chunyan

2017-06-01

A helical wire is a critical component of an unbonded flexible riser prone to fatigue failure. The helical wire has been the focus of much research work in recent years because of the complex multilayer construction of the flexible riser. The present study establishes an analytical model for the axisymmetric and bending analyses of an unbonded flexible riser. The interlayer contact under axisymmetric loads in this model is modeled by setting radial dummy springs between adjacent layers. The contact pressure is constant during the bending response and applied to determine the slipping friction force per unit helical wire. The model tracks the axial stress around the angular position at each time step to calculate the axial force gradient, then compares the axial force gradient with the slipping friction force to judge the helical wire slipping region, which would be applied to determine the bending stiffness for the next time step. The proposed model is verified against the experimental data in the literature. The bending moment-curvature relationship under irregular response is also qualitatively discussed. The stress at the critical point of the helical wire is investigated based on the model by considering the local flexure. The results indicate that the present model can well simulate the bending stiffness variation during irregular response, which has significant effect on the stress of helical wire.

Measurement and analysis of applied power, forces and material response in friction stir welding of aluminum alloy 6061

NASA Astrophysics Data System (ADS)

Avila, Ricardo E.

The process of Friction Stir Welding (FSW) 6061 aluminum alloy is investigated, with focus on the forces and power being applied in the process and the material response. The main objective is to relate measurements of the forces and power applied in the process with mechanical properties of the material during the dynamic process, based on mathematical modeling and aided by computer simulations, using the LS-DYNA software for finite element modeling. Results of measurements of applied forces and power are presented. The result obtained for applied power is used in the construction of a mechanical variational model of FSW, in which minimization of a functional for the applied torque is sought, leading to an expression for shear stress in the material. The computer simulations are performed by application of the Smoothed Particle Hydrodynamics (SPH) method, in which no structured finite element mesh is used to construct a spatial discretization of the model. The current implementation of SPH in LS-DYNA allows a structural solution using a plastic kinematic material model. This work produces information useful to improve understanding of the material flow in the process, and thus adds to current knowledge about the behavior of materials under processes of severe plastic deformation, particularly those processes in which deformation occurs mainly by application of shear stress, aided by thermoplastic strain localization and dynamic recrystallization.

Lipid Layers on Polyelectrolyte Multilayers: Understanding Lipid-Polyelectrolyte Interactions and Applications on the Surface Engineering of Nanomaterials.

PubMed

Diamanti, Eleftheria; Gregurec, Danijela; Gabriela, Romero; Cuellar, J L; Donath, E; Moya, S E

2016-06-01

In this manuscript we review work of our group on the assembly of lipid layers on top of polyelectrolyte multilayers (PEMs). The assembly of lipid layers with zwitterionic and charged lipids on PEMs is studied as a function of lipid and polyelectrolyte composition by the Quartz Crystal Microbalance. Polyelectrolyte lipid interactions are studied by means of Atomic Force Spectroscopy. We also show the coating of lipid layers for engineering different nanomaterials, i.e., carbon nanotubes and poly(lactic-co-glycolic) nanoparticles and how these can be used to decrease in vitro toxicity and to direct the intracellular localization of nanomaterials.

Dynamics of a linear system coupled to a chain of light nonlinear oscillators analyzed through a continuous approximation

NASA Astrophysics Data System (ADS)

Charlemagne, S.; Ture Savadkoohi, A.; Lamarque, C.-H.

2018-07-01

The continuous approximation is used in this work to describe the dynamics of a nonlinear chain of light oscillators coupled to a linear main system. A general methodology is applied to an example where the chain has local nonlinear restoring forces. The slow invariant manifold is detected at fast time scale. At slow time scale, equilibrium and singular points are sought around this manifold in order to predict periodic regimes and strongly modulated responses of the system. Analytical predictions are in good accordance with numerical results and represent a potent tool for designing nonlinear chains for passive control purposes.

The Prediction of the Work of Friction Force on the Arbitrary Path

ERIC Educational Resources Information Center

Matehkolaee, Mehdi Jafari; Majidian, Kourosh

2013-01-01

In this paper we have calculated the work of friction force on the arbitrary path. In our method didn't use from energy conservative conceptions any way. The distinction of this procedure is that at least do decrease measurement on the path once. Thus we can forecast the amount of work of friction force without information about speed of…

What School You Went? Local Culture, Local Identity, and Local Language: Stories of Schooling in Hawai'i

ERIC Educational Resources Information Center

Lum, Darrell H. Y.

2008-01-01

In this article, the author explores local culture and local cultural practices in an attempt to understand the forces and influences that have affected the development of a local identity as well as the persistence of Pidgin (Hawai'i Creole) as its language. The author begins with an introductory discussion of themes that emerge in two short…

Canine Supply for Physical Security: An Analysis of the Royal Australian Air Force Military Working Dog Program

DTIC Science & Technology

2016-03-01

PHYSICAL SECURITY: AN ANALYSIS OF THE ROYAL AUSTRALIAN AIR FORCE MILITARY WORKING DOG PROGRAM by Mark W. Powell March 2016 Thesis...AN ANALYSIS OF THE ROYAL AUSTRALIAN AIR FORCE MILITARY WORKING DOG PROGRAM 5. FUNDING NUMBERS 6. AUTHOR(S) Mark W. Powell 7. PERFORMING...increased demand on its physical security elements. Its military working dog (MWD) workforce is required to meet an inventory of 204 by end of year 2023 as

How institutional forces, ideas and actors shaped population health planning in Australian regional primary health care organisations.

PubMed

Javanparast, Sara; Freeman, Toby; Baum, Fran; Labonté, Ronald; Ziersch, Anna; Mackean, Tamara; Reed, Richard; Sanders, David

2018-03-20

Worldwide, there are competing norms driving health system changes and reorganisation. One such norm is that of health systems' responsibilities for population health as distinct from a focus on clinical services. In this paper we report on a case study of population health planning in Australian primary health care (PHC) organisations (Medicare Locals, 2011-2015). Drawing on institutional theory, we describe how institutional forces, ideas and actors shaped such planning. We reviewed the planning documents of the 61 Medicare Locals and rated population health activities in each Medicare Local. We also conducted an online survey and 50 interviews with Medicare Local senior staff, and an interview and focus group with Federal Department of Health staff. Despite policy emphasis on population health, Medicare Locals reported higher levels of effort and capacity in providing clinical services. Health promotion and social determinants of health activities were undertaken on an ad hoc basis. Regulatory conditions imposed by the federal government including funding priorities and time schedules, were the predominant forces constraining population health planning. In some Medicare Locals, this was in conflict with the normative values and what Medicare Locals felt ought to be done. The alignment between the governmental and the cultural-cognitive forces of a narrow biomedical approach privileged clinical practice and ascribed less legitimacy to action on social determinants of health. Our study also shed light on the range of PHC actors and how their agency influenced Medicare Locals' performance in population health. The presence of senior staff or community boards with a strong commitment to population health were important in directing action towards population health and equity. There are numerous institutional, normative and cultural factors influencing population health planning. The experience of Australian Medicare Locals highlights the difficulties of planning in such a way that the impact of the social determinants on health and health equity are taken into account. The policy environment favours a focus on clinical services to the detriment of health promotion informed by a social determinants focus.

The Law on Reduction-in-Force: A Summary of Legislation and Litigation. ERS Monograph.

ERIC Educational Resources Information Center

Zirkel, Perry A.; Bargerstock, Charles T.

Declining enrollment and lower teacher turnover have forced many school districts to reduce the number of professional personnel employed. State legislatures, the courts, and local collective negotiations have been the principal scenes of legal activity concerning reduction in force (RIF). In this monograph, both technical legal information and…

32 CFR 855.23 - Other agreements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false Other agreements. 855.23 Section 855.23 National... UNITED STATES AIR FORCE AIRFIELDS Agreements for Civil Aircraft Use of Air Force Airfields § 855.23 Other agreements. (a) Temporary use of Air Force runways occasionally is needed for extended periods when a local...

32 CFR 855.23 - Other agreements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 6 2011-07-01 2011-07-01 false Other agreements. 855.23 Section 855.23 National... UNITED STATES AIR FORCE AIRFIELDS Agreements for Civil Aircraft Use of Air Force Airfields § 855.23 Other agreements. (a) Temporary use of Air Force runways occasionally is needed for extended periods when a local...

32 CFR 855.23 - Other agreements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false Other agreements. 855.23 Section 855.23 National... UNITED STATES AIR FORCE AIRFIELDS Agreements for Civil Aircraft Use of Air Force Airfields § 855.23 Other agreements. (a) Temporary use of Air Force runways occasionally is needed for extended periods when a local...

Traceable measurements of small forces and local mechanical properties

NASA Astrophysics Data System (ADS)

Campbellová, Anna; Valtr, Miroslav; Zůda, Jaroslav; Klapetek, Petr

2011-09-01

Measurement of local mechanical properties is an important topic in the fields of nanoscale device fabrication, thin film deposition and composite material development. Nanoindentation instruments are commonly used to study hardness and related mechanical properties at the nanoscale. However, traceability and uncertainty aspects of the measurement process often remain left aside. In this contribution, the use of a commercial nanoindentation instrument for metrology purposes will be discussed. Full instrument traceability, provided using atomic force microscope cantilevers and a mass comparator (normal force), interferometer (depth) and atomic force microscope (area function) is described. The uncertainty of the loading/unloading curve measurements will be analyzed and the resulting uncertainties for quantities, that are computed from loading curves such as hardness or elastic modulus, are studied. For this calculation a combination of uncertainty propagation law and Monte Carlo uncertainty evaluations are used.

Dynamics of Andaman Sea circulation and its role in connecting the equatorial Indian Ocean to the Bay of Bengal

NASA Astrophysics Data System (ADS)

Chatterjee, Abhisek; Shankar, D.; McCreary, J. P.; Vinayachandran, P. N.; Mukherjee, A.

2017-04-01

Circulation in the Bay of Bengal (BoB) is driven not only by local winds, but are also strongly forced by the reflection of equatorial Kelvin waves (EKWs) from the eastern boundary of the Indian Ocean. The equatorial influence attains its peak during the monsoon-transition period when strong eastward currents force the strong EKWs along the equator. The Andaman Sea, lying between the Andaman and Nicobar island chains to its west and Indonesia, Thailand, and Myanmar to the south, east, and north, is connected to the equatorial ocean and the BoB by three primary passages, the southern (6°N), middle (10°N), and northern (15°N) channels. We use ocean circulation models, together with satellite altimeter data, to study the pathways by which equatorial signals pass through the Andaman Sea to the BoB and associated dynamical interactions in the process. The mean coastal circulation within the Andaman Sea and around the islands is primarily driven by equatorial forcing, with the local winds forcing a weak sea-level signal. On the other hand, the current forced by local winds is comparable to that forced remotely from the equator. Our results suggest that the Andaman and Nicobar Islands not only influence the circulation within the Andaman Sea, but also significantly alter the circulation in the interior bay and along the east coast of India, implying that they need to be represented accurately in numerical models of the Indian Ocean.

Focal Contacts as Mechanosensors

PubMed Central

Riveline, Daniel; Zamir, Eli; Balaban, Nathalie Q.; Schwarz, Ulrich S.; Ishizaki, Toshimasa; Narumiya, Shuh; Kam, Zvi; Geiger, Benjamin; Bershadsky, Alexander D.

2001-01-01

The transition of cell–matrix adhesions from the initial punctate focal complexes into the mature elongated form, known as focal contacts, requires GTPase Rho activity. In particular, activation of myosin II–driven contractility by a Rho target known as Rho-associated kinase (ROCK) was shown to be essential for focal contact formation. To dissect the mechanism of Rho-dependent induction of focal contacts and to elucidate the role of cell contractility, we applied mechanical force to vinculin-containing dot-like adhesions at the cell edge using a micropipette. Local centripetal pulling led to local assembly and elongation of these structures and to their development into streak-like focal contacts, as revealed by the dynamics of green fluorescent protein–tagged vinculin or paxillin and interference reflection microscopy. Inhibition of Rho activity by C3 transferase suppressed this force-induced focal contact formation. However, constitutively active mutants of another Rho target, the formin homology protein mDia1 (Watanabe, N., T. Kato, A. Fujita, T. Ishizaki, and S. Narumiya. 1999. Nat. Cell Biol. 1:136–143), were sufficient to restore force-induced focal contact formation in C3 transferase-treated cells. Force-induced formation of the focal contacts still occurred in cells subjected to myosin II and ROCK inhibition. Thus, as long as mDia1 is active, external tension force bypasses the requirement for ROCK-mediated myosin II contractility in the induction of focal contacts. Our experiments show that integrin-containing focal complexes behave as individual mechanosensors exhibiting directional assembly in response to local force. PMID:11402062

Does combined strength training and local vibration improve isometric maximum force? A pilot study.

PubMed

Goebel, Ruben; Haddad, Monoem; Kleinöder, Heinz; Yue, Zengyuan; Heinen, Thomas; Mester, Joachim

2017-01-01

The aim of the study was to determine whether a combination of strength training (ST) and local vibration (LV) improved the isometric maximum force of arm flexor muscles. ST was applied to the left arm of the subjects; LV was applied to the right arm of the same subjects. The main aim was to examine the effect of LV during a dumbbell biceps curl (Scott Curl) on isometric maximum force of the opposite muscle among the same subjects. It is hypothesized, that the intervention with LV produces a greater gain in isometric force of the arm flexors than ST. Twenty-seven collegiate students participated in the study. The training load was 70% of the individual 1 RM. Four sets with 12 repetitions were performed three times per week during four weeks. The right arm of all subjects represented the vibration trained body side (VS) and the left arm served as the traditional trained body side (TTS). A significant increase of isometric maximum force in both body sides (Arms) occurred. VS, however, significantly increased isometric maximum force about 43% in contrast to 22% of the TTS. The combined intervention of ST and LC improves isometric maximum force of arm flexor muscles. III.

Acute pulmonary function change associated with work on large dairies in California.

PubMed

Eastman, Chelsea; Schenker, Marc B; Mitchell, Diane C; Tancredi, Daniel J; Bennett, Deborah H; Mitloehner, Frank M

2013-01-01

To study whether dairy workers in California have lower baseline and greater cross-shift decrements in lung function than control employees. A cross-sectional study of 210 dairy and 47 control workers who completed questionnaires and spirometry before and after the work shift. Dairy work was associated with mean baseline differences of -0.132 L (P = 0.07) and -0.131 L (P = 0.13) in forced expiratory volume in 1 second and forced vital capacity, respectively, compared with control employees, adjusting for age, height, smoking status, and days back at work since last day off. Dairy work was associated with a mean cross-shift difference of -65.2 mL (P = 0.02) and -103.1 mL (P < 0.01) in forced expiratory volume in 1 second and forced vital capacity, respectively, adjusting for smoking status and work-shift time. Dairy work in California was associated with mild acute airway obstruction. The unclear long-term effect of dairy work in California merits further investigation.

Predicting the 3D fatigue crack growth rate of small cracks using multimodal data via Bayesian networks: In-situ experiments and crystal plasticity simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rovinelli, Andrea; Sangid, Michael D.; Proudhon, Henry

Small crack propagation accounts for most of the fatigue life of engineering structures subject to high cycle fatigue loading conditions. Determining the fatigue crack growth rate of small cracks propagating into polycrystalline engineering alloys is critical to improving fatigue life predictions, thus lowering cost and increasing safety. In this work, cycle-by-cycle data of a small crack propagating in a beta metastable titanium alloy is available via phase and diffraction contrast tomography. Crystal plasticity simulations are used to supplement experimental data regarding the micromechanical fields ahead of the crack tip. Experimental and numerical results are combined into a multimodal dataset andmore » sampled utilizing a non-local data mining procedure. Furthermore, to capture the propensity of body-centered cubic metals to deform according to the pencil-glide model, a non-local driving force is postulated. The proposed driving force serves as the basis to construct a data-driven probabilistic crack propagation framework using Bayesian networks as building blocks. The spatial correlation between the postulated driving force and experimental observations is obtained by analyzing the results of the proposed framework. Results show that the above correlation increases proportionally to the distance from the crack front until the edge of the plastic zone. Moreover, the predictions of the propagation framework show good agreement with experimental observations. Finally, we studied the interaction of a small crack with grain boundaries (GBs) utilizing various slip transmission criteria, revealing the tendency of a crack to cross a GB by propagating along the slip directions minimizing the residual Burgers vector within the GB.« less

Predicting the 3D fatigue crack growth rate of small cracks using multimodal data via Bayesian networks: In-situ experiments and crystal plasticity simulations

NASA Astrophysics Data System (ADS)

Rovinelli, Andrea; Sangid, Michael D.; Proudhon, Henry; Guilhem, Yoann; Lebensohn, Ricardo A.; Ludwig, Wolfgang

2018-06-01

Small crack propagation accounts for most of the fatigue life of engineering structures subject to high cycle fatigue loading conditions. Determining the fatigue crack growth rate of small cracks propagating into polycrystalline engineering alloys is critical to improving fatigue life predictions, thus lowering cost and increasing safety. In this work, cycle-by-cycle data of a small crack propagating in a beta metastable titanium alloy is available via phase and diffraction contrast tomography. Crystal plasticity simulations are used to supplement experimental data regarding the micromechanical fields ahead of the crack tip. Experimental and numerical results are combined into a multimodal dataset and sampled utilizing a non-local data mining procedure. Furthermore, to capture the propensity of body-centered cubic metals to deform according to the pencil-glide model, a non-local driving force is postulated. The proposed driving force serves as the basis to construct a data-driven probabilistic crack propagation framework using Bayesian networks as building blocks. The spatial correlation between the postulated driving force and experimental observations is obtained by analyzing the results of the proposed framework. Results show that the above correlation increases proportionally to the distance from the crack front until the edge of the plastic zone. Moreover, the predictions of the propagation framework show good agreement with experimental observations. Finally, we studied the interaction of a small crack with grain boundaries (GBs) utilizing various slip transmission criteria, revealing the tendency of a crack to cross a GB by propagating along the slip directions minimizing the residual Burgers vector within the GB.

Good research practices for measuring drug costs in cost-effectiveness analyses: an international perspective: the ISPOR Drug Cost Task Force report--Part VI.

PubMed

Shi, Lizheng; Hodges, Meredith; Drummond, Michael; Ahn, Jeonghoon; Li, Shu Chuen; Hu, Shanlian; Augustovski, Federico; Hay, Joel W; Smeeding, Jim

2010-01-01

The pharmacoeconomic guidelines available in the literature or promulgated in many countries are either vague or silent about how drug costs should be established or measured so an international comparison of cost-effectiveness analysis (CEA) results can be made. The objective of this report is to provide guidance and recommendations on how drug costs should be measured for CEAs done from an internationally comparative perspective. Members of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Task Force on Good Research Practices-Use of Drug Costs for Cost Effectiveness Analysis (Drug Cost Task Force [DCTF]) subgroup from several countries were experienced developers or users of CEA models, and worked in academia, industry, and as advisors to governments. They solicited comments on drafts from a core group of 174 external reviewers and more broadly, from the members of the ISPOR at the ISPOR 12th Annual International meeting and via the ISPOR Web site. Drug units should be standardized in terms of volume of active ingredient, regardless of packaging and dosing strength variations across countries. Drug costs should be measured in local currency per unit of active ingredient and should be converted to other currencies using sensitivity analyses of purchasing power parities (PPP) and exchange rates, whichever is more appropriate. When using drug prices from different years, the consumer price index for the local currency should be applied before the PPP and/or exchange rate conversion. CEA researchers conducting international pharmacoeconomic analysis should tailor the appropriate measure of drug costs to the international perspective, to maintain clarity and transparency on drug cost measurement in the context of international drug comparison and report the sensitivity of CEA results to reasonable cost conversions.

Mapping the Influence of Prior Tectonism on Seismicity in the Central and Eastern US

NASA Astrophysics Data System (ADS)

Boyd, O. S.; Levandowski, W.; Ramirez-Guzman, L.; Zellman, M.; Briggs, R.

2015-12-01

From the Atlantic margin to the Rockies, most earthquakes in the central and eastern U.S. occur in ancient tectonic zones, yet many such features have been historically quiescent. If all intraplate stress were transferred from plate boundaries or bases, the stress field would be broadly uniform, with all well-oriented faults equally likely to slip. But faults are not the only product of tectonism; intrusions, metamorphism, or any number of other alterations may modify crustal and/or upper mantle density, leaving behind lithostatic pressure gradients that can locally elevate or reduce stress on faults. With data provided by Earthscope, we are working to map lithospheric density across the U.S. and to quantify gravitational body-forces using analytical and finite-element methods. Regional-scale 3D models show that gravitational forces focus seismicity and reorient principal stress both in the New Madrid seismic zone and the western Great Plains. Sedimentary fill and low elevation encourage Reelfoot Rift-normal contraction, yet along-strike variations in lower crustal density rotate body-forces beneath New Madrid to interfere constructively with far-field compression, augmenting differential stress by 5-10 MPa. On the plains of SE Colorado and SE Wyoming, the Cheraw and Wheatland/Whalen faults collocate with multiply reactivated Proterozoic sutures, enigmatic Quaternary extension, and focused seismicity with regionally anomalous NW-SE moment tensor T-axes. Earthscope data help reveal anomalously buoyant lower crust beneath each suture -­- which we hypothesize reflects hydration by Farallon slab-derived fluids that have preferentially migrated along ancient fracture networks -- that generates 10 MPa of localized suture-normal tension, consistent with geomorphic strain- and seismic stress-indicators. As continent-wide seismic models emerge from Earthscope data, we will continue to map regions where inherited structures encourage intraplate seismicity.

Sensitivity analysis of a new dual-porosity hydroloigcal model coupled with the SOSlope model for the numerical simulations of rainfall triggered shallow landslides.

NASA Astrophysics Data System (ADS)

Schwarz, Massimiliano; Cohen, Denis

2017-04-01

Morphology and extent of hydrological pathways, in combination with the spatio-temporal variability of rainfall events and the heterogeneities of hydro-mechanical properties of soils, has a major impact on the hydrological conditions that locally determine the triggering of shallow landslides. The coupling of these processes at different spatial scales is an enormous challenge for slope stability modeling at the catchment scale. In this work we present a sensitivity analysis of a new dual-porosity hydrological model implemented in the hydro-mechanical model SOSlope for the modeling of shallow landslides on vegetated hillslopes. The proposed model links the calculation of the saturation dynamic of preferential flow-paths based on hydrological and topographical characteristics of the landscape to the hydro-mechanical behavior of the soil along a potential failure surface due to the changes of soil matrix saturation. Furthermore, the hydro-mechanical changes of soil conditions are linked to the local stress-strain properties of the (rooted-)soil that ultimately determine the force redistribution and related deformations at the hillslope scale. The model considers forces to be redistributed through three types of solicitations: tension, compression, and shearing. The present analysis shows how the conditions of deformation due to the passive earth pressure mobilized at the toe of the landslide are particularly important in defining the timing and extension of shallow landslides. The model also shows that, in densely rooted hillslopes, lateral force redistribution under tension through the root-network may substantially contribute to stabilizing slopes, avoiding crack formation and large deformations. The results of the sensitivity analysis are discussed in the context of protection forest management and bioengineering techniques.

Predicting the 3D fatigue crack growth rate of small cracks using multimodal data via Bayesian networks: In-situ experiments and crystal plasticity simulations

DOE PAGES

Rovinelli, Andrea; Sangid, Michael D.; Proudhon, Henry; ...

2018-03-11

Small crack propagation accounts for most of the fatigue life of engineering structures subject to high cycle fatigue loading conditions. Determining the fatigue crack growth rate of small cracks propagating into polycrystalline engineering alloys is critical to improving fatigue life predictions, thus lowering cost and increasing safety. In this work, cycle-by-cycle data of a small crack propagating in a beta metastable titanium alloy is available via phase and diffraction contrast tomography. Crystal plasticity simulations are used to supplement experimental data regarding the micromechanical fields ahead of the crack tip. Experimental and numerical results are combined into a multimodal dataset andmore » sampled utilizing a non-local data mining procedure. Furthermore, to capture the propensity of body-centered cubic metals to deform according to the pencil-glide model, a non-local driving force is postulated. The proposed driving force serves as the basis to construct a data-driven probabilistic crack propagation framework using Bayesian networks as building blocks. The spatial correlation between the postulated driving force and experimental observations is obtained by analyzing the results of the proposed framework. Results show that the above correlation increases proportionally to the distance from the crack front until the edge of the plastic zone. Moreover, the predictions of the propagation framework show good agreement with experimental observations. Finally, we studied the interaction of a small crack with grain boundaries (GBs) utilizing various slip transmission criteria, revealing the tendency of a crack to cross a GB by propagating along the slip directions minimizing the residual Burgers vector within the GB.« less

Linking Federal, State, and Local Adaptation Strategies in New York (Invited)

NASA Astrophysics Data System (ADS)

Rosenzweig, C.

2010-12-01

New York City and New York State are leaders in adaptation in the U.S. In 2008 Mayor Bloomberg convened the NYC Climate Change Adaptation Task Force and the New York City Panel on Climate Change (NPCC). Also in 2008, the New York State Energy Research and Development Authority (NYSERDA) initiated the Integrated Assessment for Effective Climate Change Adaptation Strategies (ClimAID), to provide New York State decision-makers with cutting-edge information on its vulnerability to climate change and to facilitate the development of adaptation strategies informed by both local experience and scientific knowledge. The two efforts are working together to develop effective adaptation strategies across multiple jurisdictions. The New York Task Force consists of approximate 40 city, state, and federal agencies, regional public authorities, and private companies that operate, maintain, or regulate critical infrastructure in the region. The NPCC consisted of climate change and impacts scientists, and legal, insurance, and risk-management experts and served as the technical advisory body for the Mayor and the Task Force on issues related to climate change, impacts, and adaptation. In its 2010 report, the NPCC recommended adoption of a risk-based approach to climate change; creation of a monitoring program to track and analyze key climate change factors, impacts, and adaptation indicators; review of relevant standards and codes; inclusion of multiple layers of government and a wide range of public and private stakeholder experts to build buy-in; and formation of crucial partnerships for development of coordinated adaptation strategies. The task now is for these partnerships to create pilot programs that move adaptation from the planning phase to implementation; urban areas can provide critical ‘test-beds’ for such efforts.

The relative importance among anthropogenic forcings of land use/land cover change in affecting temperature extremes

NASA Astrophysics Data System (ADS)

Chen, Liang; Dirmeyer, Paul A.

2018-05-01

Land use/land cover change (LULCC) exerts significant influence on regional climate extremes, but its relative importance compared with other anthropogenic climate forcings has not been thoroughly investigated. This study compares land use forcing with other forcing agents in explaining the simulated historical temperature extreme changes since preindustrial times in the CESM-Last Millennium Ensemble (LME) project. CESM-LME suggests that the land use forcing has caused an overall cooling in both warm and cold extremes, and has significantly decreased diurnal temperature range (DTR). Due to the competing effects of the GHG and aerosol forcings, the spatial pattern of changes in 1850-2005 climatology of temperature extremes in CESM-LME can be largely explained by the land use forcing, especially for hot extremes and DTR. The dominance of land use forcing is particularly evident over Europe, eastern China, and the central and eastern US. Temporally, the land-use cooling is relatively stable throughout the historical period, while the warming of temperature extremes is mainly influenced by the enhanced GHG forcing, which has gradually dampened the local dominance of the land use effects. Results from the suite of CMIP5 experiments partially agree with the local dominance of the land use forcing in CESM-LME, but inter-model discrepancies exist in the distribution and sign of the LULCC-induced temperature changes. Our results underline the overall importance of LULCC in historical temperature extreme changes, implying land use forcing should be highlighted in future climate projections.

Forces on stationary particles in near-bed turbulent flows

NASA Astrophysics Data System (ADS)

Schmeeckle, Mark W.; Nelson, Jonathan M.; Shreve, Ronald L.

2007-06-01

In natural flows, bed sediment particles are entrained and moved by the fluctuating forces, such as lift and drag, exerted by the overlying flow on the particles. To develop a better understanding of these forces and the relation of the forces to the local flow, the downstream and vertical components of force on near-bed fixed particles and of fluid velocity above or in front of them were measured synchronously at turbulence-resolving frequencies (200 or 500 Hz) in a laboratory flume. Measurements were made for a spherical test particle fixed at various heights above a smooth bed, above a smooth bed downstream of a downstream-facing step, and in a gravel bed of similarly sized particles as well as for a cubical test particle and 7 natural particles above a smooth bed. Horizontal force was well correlated with downstream velocity and not correlated with vertical velocity or vertical momentum flux. The standard drag formula worked well to predict the horizontal force, but the required value of the drag coefficient was significantly higher than generally used to model bed load motion. For the spheres, cubes, and natural particles, average drag coefficients were found to be 0.76, 1.36, and 0.91, respectively. For comparison, the drag coefficient for a sphere settling in still water at similar particle Reynolds numbers is only about 0.4. The variability of the horizontal force relative to its mean was strongly increased by the presence of the step and the gravel bed. Peak deviations were about 30% of the mean force for the sphere over the smooth bed, about twice the mean with the step, and 4 times it for the sphere protruding roughly half its diameter above the gravel bed. Vertical force correlated poorly with downstream velocity, vertical velocity, and vertical momentum flux whether measured over or ahead of the test particle. Typical formulas for shear-induced lift based on Bernoulli's principle poorly predict the vertical forces on near-bed particles. The measurements suggest that particle-scale pressure variations associated with turbulence are significant in the particle momentum balance.

Forces on stationary particles in near-bed turbulent flows

USGS Publications Warehouse

Schmeeckle, M.W.; Nelson, J.M.; Shreve, R.L.

2007-01-01

In natural flows, bed sediment particles are entrained and moved by the fluctuating forces, such as lift and drag, exerted by the overlying flow on the particles. To develop a better understanding of these forces and the relation of the forces to the local flow, the downstream and vertical components of force on near-bed fixed particles and of fluid velocity above or in front of them were measured synchronously at turbulence-resolving frequencies (200 or 500 Hz) in a laboratory flume. Measurements were made for a spherical test particle fixed at various heights above a smooth bed, above a smooth bed downstream of a downstream-facing step, and in a gravel bed of similarly sized particles as well as for a cubical test particle and 7 natural particles above a smooth bed. Horizontal force was well correlated with downstream velocity and not correlated with vertical velocity or vertical momentum flux. The standard drag formula worked well to predict the horizontal force, but the required value of the drag coefficient was significantly higher than generally used to model bed load motion. For the spheres, cubes, and natural particles, average drag coefficients were found to be 0.76, 1.36, and 0.91, respectively. For comparison, the drag coefficient for a sphere settling in still water at similar particle Reynolds numbers is only about 0.4. The variability of the horizontal force relative to its mean was strongly increased by the presence of the step and the gravel bed. Peak deviations were about 30% of the mean force for the sphere over the smooth bed, about twice the mean with the step, and 4 times it for the sphere protruding roughly half its diameter above the gravel bed. Vertical force correlated poorly with downstream velocity, vertical velocity, and vertical momentum flux whether measured over or ahead of the test particle. Typical formulas for shear-induced lift based on Bernoulli's principle poorly predict the vertical forces on near-bed particles. The measurements suggest that particle-scale pressure variations associated with turbulence are significant in the particle momentum balance. Copyright 2007 by the American Geophysical Union.

Evolution of Metastable Defects and Its Effect on the Electronic Properties of MoS 2 Films

DOE PAGES

Precner, Marian; Polakovic, T.; Qiao, Qiao; ...

2018-04-30

Here, we report on structural and electronic properties of defects in chemical vapor-deposited monolayer and few-layer MoS 2 films. Scanning tunneling microscopy, Kelvin probe force microscopy, and transmission electron microscopy were used to obtain high resolution images and quantitative measurements of the local density of states, work function and nature of defects in MoS 2 films. We track the evolution of defects that are formed under heating and electron beam irradiation. We observe formation of metastable domains with different work function values after annealing the material in ultra-high vacuum to moderate temperatures. We attribute these metastable values of the workmore » function to evolution of crystal defects forming during the annealing. The experiments show that sulfur vacancies formed after exposure to elevated temperatures diffuse, coalesce, and migrate bringing the system from a metastable to equilibrium ground state. The process could be thermally or e-beam activated with estimated energy barrier for sulfur vacancy migration of 0.6 eV in single unit cell MoS 2. Even at equilibrium conditions, the work function and local density of states values are strongly affected near grain boundaries and edges. The results provide initial estimates of the thermal budgets available for reliable fabrication of MoS 2-based integrated electronics and indicate the importance of defect control and layer passivation.« less

Evolution of Metastable Defects and Its Effect on the Electronic Properties of MoS 2 Films

DOE Office of Scientific and Technical Information (OSTI.GOV)

Precner, Marian; Polakovic, T.; Qiao, Qiao

Here, we report on structural and electronic properties of defects in chemical vapor-deposited monolayer and few-layer MoS 2 films. Scanning tunneling microscopy, Kelvin probe force microscopy, and transmission electron microscopy were used to obtain high resolution images and quantitative measurements of the local density of states, work function and nature of defects in MoS 2 films. We track the evolution of defects that are formed under heating and electron beam irradiation. We observe formation of metastable domains with different work function values after annealing the material in ultra-high vacuum to moderate temperatures. We attribute these metastable values of the workmore » function to evolution of crystal defects forming during the annealing. The experiments show that sulfur vacancies formed after exposure to elevated temperatures diffuse, coalesce, and migrate bringing the system from a metastable to equilibrium ground state. The process could be thermally or e-beam activated with estimated energy barrier for sulfur vacancy migration of 0.6 eV in single unit cell MoS 2. Even at equilibrium conditions, the work function and local density of states values are strongly affected near grain boundaries and edges. The results provide initial estimates of the thermal budgets available for reliable fabrication of MoS 2-based integrated electronics and indicate the importance of defect control and layer passivation.« less

Theoretical Models for Surface Forces and Adhesion and Their Measurement Using Atomic Force Microscopy

PubMed Central

Leite, Fabio L.; Bueno, Carolina C.; Da Róz, Alessandra L.; Ziemath, Ervino C.; Oliveira, Osvaldo N.

2012-01-01

The increasing importance of studies on soft matter and their impact on new technologies, including those associated with nanotechnology, has brought intermolecular and surface forces to the forefront of physics and materials science, for these are the prevailing forces in micro and nanosystems. With experimental methods such as the atomic force spectroscopy (AFS), it is now possible to measure these forces accurately, in addition to providing information on local material properties such as elasticity, hardness and adhesion. This review provides the theoretical and experimental background of AFS, adhesion forces, intermolecular interactions and surface forces in air, vacuum and in solution. PMID:23202925

Automated parameterization of intermolecular pair potentials using global optimization techniques

NASA Astrophysics Data System (ADS)

Krämer, Andreas; Hülsmann, Marco; Köddermann, Thorsten; Reith, Dirk

2014-12-01

In this work, different global optimization techniques are assessed for the automated development of molecular force fields, as used in molecular dynamics and Monte Carlo simulations. The quest of finding suitable force field parameters is treated as a mathematical minimization problem. Intricate problem characteristics such as extremely costly and even abortive simulations, noisy simulation results, and especially multiple local minima naturally lead to the use of sophisticated global optimization algorithms. Five diverse algorithms (pure random search, recursive random search, CMA-ES, differential evolution, and taboo search) are compared to our own tailor-made solution named CoSMoS. CoSMoS is an automated workflow. It models the parameters' influence on the simulation observables to detect a globally optimal set of parameters. It is shown how and why this approach is superior to other algorithms. Applied to suitable test functions and simulations for phosgene, CoSMoS effectively reduces the number of required simulations and real time for the optimization task.

Sensitive Detection of Small Particles in Fluids Using Optical Fiber Tip with Dielectrophoresis

PubMed Central

Tai, Yi-Hsin; Chang, Dao-Ming; Pan, Ming-Yang; Huang, Ding-Wei; Wei, Pei-Kuen

2016-01-01

This work presents using a tapered fiber tip coated with thin metallic film to detect small particles in water with high sensitivity. When an AC voltage applied to the Ti/Al coated fiber tip and indium tin oxide (ITO) substrate, a gradient electric field at the fiber tip induced attractive/repulsive force to suspended small particles due to the frequency-dependent dielectrophoresis (DEP) effect. Such DEP force greatly enhanced the concentration of the small particles near the tip. The increase of the local concentration also increased the scattering of surface plasmon wave near the fiber tip. Combined both DEP effect and scattering optical near-field, we show the detection limit of the concentration for 1.36 μm polystyrene beads can be down to 1 particle/mL. The detection limit of the Escherichia coli (E. coli) bacteria was 20 CFU/mL. The fiber tip sensor takes advantages of ultrasmall volume, label-free and simple detection system. PMID:26927128

Non-equilibrium fluctuations of a semi-flexible filament driven by active cross-linkers

NASA Astrophysics Data System (ADS)

Weber, I.; Appert-Rolland, C.; Schehr, G.; Santen, L.

2017-11-01

The cytoskeleton is an inhomogeneous network of semi-flexible filaments, which are involved in a wide variety of active biological processes. Although the cytoskeletal filaments can be very stiff and embedded in a dense and cross-linked network, it has been shown that, in cells, they typically exhibit significant bending on all length scales. In this work we propose a model of a semi-flexible filament deformed by different types of cross-linkers for which one can compute and investigate the bending spectrum. Our model allows to couple the evolution of the deformation of the semi-flexible polymer with the stochastic dynamics of linkers which exert transversal forces onto the filament. We observe a q-2 dependence of the bending spectrum for some biologically relevant parameters and in a certain range of wave numbers q, as observed in some experiments. However, generically, the spatially localized forcing and the non-thermal dynamics both introduce deviations from the thermal-like q-2 spectrum.

Electrostatic nanolithography in polymer materials: an alternative technique for nanostructures formation

NASA Astrophysics Data System (ADS)

Lyuksyutov, Sergei F.; Paramonov, Pavel B.; Sigalov, Grigori; Vaia, Richard A.; Juhl, Shane; Sancaktar, Erol

2003-10-01

The combination of localized softening attolitres (10^2 -10^4) of polymer film by Jule heating, extremely non-uniform electric field gradients to polarize and manipulate the soften polymer, and single step technique using conventional atomic force microscopy (AFM), establishes a new paradigm for nanolithography in a broad class of polymer materials allowing rapid (order of milliseconds) creation of raised and depressed nanostructures without external heating of a polymer film of AFM tip-film contact [1]. In this work we present recent studies of AFM-assisted electrostatic nanolithography (AFMEN) such as amplitude-modulated AFMEN, and the humidity influence on nanostructures formation during contact mode AFMEN. It has been shown that the aspect ratio of nanostructures grows on the order of magnitude (0.2), while the lateral dimensions of nanodots decreases down to 10-15 nm. [1] S.F. Lyuksyutov, R.A. Vaia, P.B. Paramonov, S. Juhl, L. Waterhouse, R.M. Ralich, G. Sigalov, and E. Sancaktar, "Electrostatic nanolithography in polymers using atomic force microscopy," Nature Materials 2, 468-472 (2003)

Atomic force microscopy recognition of protein A on Staphylococcus aureus cell surfaces by labelling with IgG-Au conjugates.

PubMed

Tatlybaeva, Elena B; Nikiyan, Hike N; Vasilchenko, Alexey S; Deryabin, Dmitri G

2013-01-01

The labelling of functional molecules on the surface of bacterial cells is one way to recognize the bacteria. In this work, we have developed a method for the selective labelling of protein A on the cell surfaces of Staphylococcus aureus by using nanosized immunogold conjugates as cell-surface markers for atomic force microscopy (AFM). The use of 30-nm size Au nanoparticles conjugated with immunoglobulin G (IgG) allowed the visualization, localization and distribution of protein A-IgG complexes on the surface of S. aureus. The selectivity of the labelling method was confirmed in mixtures of S. aureus with Bacillus licheniformis cells, which differed by size and shape and had no IgG receptors on the surface. A preferential binding of the IgG-Au conjugates to S. aureus was obtained. Thus, this novel approach allows the identification of protein A and other IgG receptor-bearing bacteria, which is useful for AFM indication of pathogenic microorganisms in poly-component associations.

Photonic Landau levels on cones

NASA Astrophysics Data System (ADS)

Schine, Nathan; Ryou, Albert; Gromov, Andrey; Sommer, Ariel; Simon, Jonathan

2016-05-01

We present the first experimental realization of a bulk magnetic field for optical photons. By using a non-planar ring resonator, we induce an image rotation on each round trip through the resonator. This results in a Coriolis/Lorentz force and a centrifugal anticonfining force, the latter of which is cancelled by mirror curvature. Using a digital micromirror device to control both amplitude and phase, we inject arbitrary optical modes into our resonator. Spatial- and energy- resolved spectroscopy tracks photonic eigenstates as residual trapping is reduced, and we observe photonic Landau levels as the eigenstates become degenerate. We show that there is a conical geometry of the resulting manifold for photon dynamics and present a measurement of the local density of states that is consistent with Landau levels on a cone. While our work already demonstrates an integer quantum Hall material composed of photons, we have ensured compatibility with strong photon-photon interactions, which will allow quantum optical studies of entanglement and correlation in manybody systems including fractional quantum Hall fluids.

Trapped atomic ions for quantum-limited metrology

NASA Astrophysics Data System (ADS)

Wineland, David

2017-04-01

Laser-beam-manipulated trapped ions are a candidate for large-scale quantum information processing and quantum simulation but the basic techniques used can also be applied to quantum-limited metrology and sensing. Some examples being explored at NIST are: 1) As charged harmonic oscillators, trapped ions can be used to sense electric fields; this can be used to characterize the electrode-surface-based noisy electric fields that compromise logic-gate fidelities and may eventually be used as a tool in surface science. 2) Since typical qubit logic gates depend on state-dependent forces, we can adapt the gate dynamics to sensitively detect additional forces. 3) We can use extensions of Bell inequality measurements to further restrict the degree of local realism possessed by Bell states. 4) We also briefly describe experiments for creation of Bell states using Hilbert space engineering. This work is a joint effort including the Ion-Storage group, the Quantum processing group, and the Computing and Communications Theory group at NIST, Boulder. Supported by IARPA, ONR, and the NIST Quantum Information Program.

Towards a complete caracterisation of Ganymede's environnement

NASA Astrophysics Data System (ADS)

Cessateur, Gaël; Barthélémy, Mathieu; Lilensten, Jean; Dudok de Wit, Thierry; Kretzschmar, Matthieu; Mbemba Kabuiku, Lydie

2013-04-01

In the framework to the JUICE mission to the Jovian system, a complete picture of the interaction between Ganymede's atmosphere and external forcing is needed. This will definitely allow us to constrain instrument performances according to the mission objectives. The main source of information regarding the upper atmosphere is the non LTE UV-Visible-near IR emissions. Those emissions are both induce by the incident solar UV flux and particle precipitations. This work aims at characterizing the impact from those external forcing, and then at deriving some key physical parameters that are measurable by an orbiter, namely the oxygen red line at 630 nm or the resonant oxygen line at 130 nm for example. We will also present the 4S4J instrument, a proposed EUV radiometer, which will provides the solar local EUV flux, an invaluable parameter for the JUICE mission. Based on new technologies and a new design, only two passbands are considered for reconstructing the whole EUV spectrum.

Theoretical analysis of non-linear Joule heating effects over an electro-thermal patterned flow

NASA Astrophysics Data System (ADS)

Sanchez, Salvador; Ascanio, Gabriel; Mendez, Federico; Bautista, Oscar

2017-11-01

In this work, non-linear Joule heating effects for electro-thermal patterned flows driven inside of a slit microchannel are analyzed. Here, the movement of fluids is controlled by placing electro-thermal forces, which are generated through an imposed longitudinal electric field, E0, and the wall electric potential produced by electrodes inserted along the surface of the microchannel wall, ζ. For this analysis, viscosity and electrical conductivity of fluids are included as known functions, which depend on the temperature; therefore, in order to determine the flow, temperature and electric potential fields together with its simultaneous interactions, the equations of continuity, momentum, energy, charges distribution and electrical current have to be solved in a coupled manner. The main results obtained in the study reveal that with the presence of thermal gradients along of the microchannel, local electro-thermal forces, Fχ, are affected in a sensible manner, and consequently, the flow field is modified substantially, causing the interruption or intensification of recirculations along of the microchannel. This work was supported by the Fondo SEP-CONACYT through research Grants No. 220900 and 20171181 from SIP-IPN. F. Mendez acknowledges support from PAPIIT-UNAM under Contract Number IN112215. S. Sanchez thanks to DGAPA-UNAM for the postdoctoral fellowship.

On configurational forces for gradient-enhanced inelasticity

NASA Astrophysics Data System (ADS)

Floros, Dimosthenis; Larsson, Fredrik; Runesson, Kenneth

2018-04-01

In this paper we discuss how configurational forces can be computed in an efficient and robust manner when a constitutive continuum model of gradient-enhanced viscoplasticity is adopted, whereby a suitably tailored mixed variational formulation in terms of displacements and micro-stresses is used. It is demonstrated that such a formulation produces sufficient regularity to overcome numerical difficulties that are notorious for a local constitutive model. In particular, no nodal smoothing of the internal variable fields is required. Moreover, the pathological mesh sensitivity that has been reported in the literature for a standard local model is no longer present. Numerical results in terms of configurational forces are shown for (1) a smooth interface and (2) a discrete edge crack. The corresponding configurational forces are computed for different values of the intrinsic length parameter. It is concluded that the convergence of the computed configurational forces with mesh refinement depends strongly on this parameter value. Moreover, the convergence behavior for the limit situation of rate-independent plasticity is unaffected by the relaxation time parameter.

Tip localization of an atomic force microscope in transmission microscopy with nanoscale precision

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baumann, Fabian; Pippig, Diana A., E-mail: diana.pippig@physik.uni-muenchen.de; Gaub, Hermann E.

Since the atomic force microscope (AFM) has evolved into a general purpose platform for mechanical experiments at the nanoscale, the need for a simple and generally applicable localization of the AFM cantilever in the reference frame of an optical microscope has grown. Molecular manipulations like in single molecule cut and paste or force spectroscopy as well as tip mediated nanolithography are prominent examples for the broad variety of applications implemented to date. In contrast to the different kinds of superresolution microscopy where fluorescence is used to localize the emitter, we, here, employ the absorbance of the tip to localize itsmore » position in transmission microscopy. We show that in a low aperture illumination, the tip causes a significant reduction of the intensity in the image plane of the microscope objective when it is closer than a few hundred nm. By independently varying the z-position of the sample slide, we could verify that this diffraction limited image of the tip is not caused by a near field effect but is rather caused by the absorbance of the transmitted light in the low apex needle-like tip. We localized the centroid position of this tip image with a precision of better than 6 nm and used it in a feedback loop to position the tip into nano-apertures of 110 nm radius. Single-molecule force spectroscopy traces on the unfolding of individual green fluorescent proteins within the nano-apertures showed that their center positions were repeatedly approached with very high fidelity leaving the specific handle chemistry on the tip’s surface unimpaired.« less

Receiving treatment, labor force activity, and work performance among people with psychiatric disorders: results from a population survey.

PubMed

Waghorn, Geoffrey; Chant, David

2011-12-01

Standard treatments for psychiatric disorders such as schizophrenia, depression and anxiety disorders are generally expected to benefit individuals, employers, and the wider community through improvements in work-functioning and productivity. We repeated a previous secondary investigation of receiving treatment, labor force activity and self-reported work performance among people with ICD-10 psychiatric disorders, in comparison to people with other types of health conditions. Data were collected by the Australian Bureau of Statistics in 2003 repeating a survey administered in 1998 using representative multistage sampling strategies. The 2003 household probability sample consisted of 36,241 working age individuals. Consistent with the previous secondary investigation based on the 1998 survey administration, receiving treatment was consistently associated with non-participation in the labor force, and was negatively associated with work performance. At a population level, receiving treatment was negatively associated with labor force activity and work performance. The stability of these results in two independent surveys highlights the need to investigate the longitudinal relationships between evidence-based treatments for psychiatric conditions as applied in real-world settings, and labor force participation and work performance outcomes.

Force and work to shear green southern pine logs at slow speed

Treesearch

Peter Koch

1971-01-01

When logs of three diameter classes and two specific gravity classes were sheared with a 3/8-inch-thick knife travelling at 2 inches per minute, shearing force and work averaged greatest for dense 13.6-inch logs cut with a knife having a 45o sharpness angle (73,517 pounds; 49,838 foot-pounds). Force and work averaged at least 5.1-inch bolts of...

Balance between cell-substrate adhesion and myosin contraction determines the frequency of motility initiation in fish keratocytes.

PubMed

Barnhart, Erin; Lee, Kun-Chun; Allen, Greg M; Theriot, Julie A; Mogilner, Alex

2015-04-21

Cells are dynamic systems capable of spontaneously switching among stable states. One striking example of this is spontaneous symmetry breaking and motility initiation in fish epithelial keratocytes. Although the biochemical and mechanical mechanisms that control steady-state migration in these cells have been well characterized, the mechanisms underlying symmetry breaking are less well understood. In this work, we have combined experimental manipulations of cell-substrate adhesion strength and myosin activity, traction force measurements, and mathematical modeling to develop a comprehensive mechanical model for symmetry breaking and motility initiation in fish epithelial keratocytes. Our results suggest that stochastic fluctuations in adhesion strength and myosin localization drive actin network flow rates in the prospective cell rear above a critical threshold. Above this threshold, high actin flow rates induce a nonlinear switch in adhesion strength, locally switching adhesions from gripping to slipping and further accelerating actin flow in the prospective cell rear, resulting in rear retraction and motility initiation. We further show, both experimentally and with model simulations, that the global levels of adhesion strength and myosin activity control the stability of the stationary state: The frequency of symmetry breaking decreases with increasing adhesion strength and increases with increasing myosin contraction. Thus, the relative strengths of two opposing mechanical forces--contractility and cell-substrate adhesion--determine the likelihood of spontaneous symmetry breaking and motility initiation.

A Study on Flexural Properties of Sandwich Structures with Fiber/Metal Laminate Face Sheets

NASA Astrophysics Data System (ADS)

Dariushi, S.; Sadighi, M.

2013-10-01

In this work, a new family of sandwich structures with fiber metal laminate (FML) faces is investigated. FMLs have benefits over both metal and fiber reinforced composites. To investigate the bending properties of sandwich beams with FML faces and compare with similar sandwich beams with fibrous composite faces, 6 groups of specimen with different layer arrangements were made and tested. Results show that FML faces have good resistance against transverse local loads and minimize stress concentration and local deformations of skin and core under the loading tip. In addition, FML faces have a good integrity even after plateau region of foam cores and prevent from catastrophic failures, which cannot be seen in fibrous composite faces. Also, FML faces are lighter than metal faces and have better connection with foam cores. Sandwich beams with FML faces have a larger elastic region because of simultaneous deformation of top and bottom faces and larger failure strain thanks to good durability of FMLs. A geometrical nonlinear classical theory is used to predict force-deflection behavior. In this model an explicit formula between symmetrical sandwich beams deflections and applied force which can be useful for designers, is derived. Good agreement is obtained between the analytical predictions and experimental results. Also, analytical results are compared with small deformation solution in a parametric study, and the effects of geometric parameters on difference between linear and nonlinear results are discussed.

Medical image registration by combining global and local information: a chain-type diffeomorphic demons algorithm.

PubMed

Liu, Xiaozheng; Yuan, Zhenming; Zhu, Junming; Xu, Dongrong

2013-12-07

The demons algorithm is a popular algorithm for non-rigid image registration because of its computational efficiency and simple implementation. The deformation forces of the classic demons algorithm were derived from image gradients by considering the deformation to decrease the intensity dissimilarity between images. However, the methods using the difference of image intensity for medical image registration are easily affected by image artifacts, such as image noise, non-uniform imaging and partial volume effects. The gradient magnitude image is constructed from the local information of an image, so the difference in a gradient magnitude image can be regarded as more reliable and robust for these artifacts. Then, registering medical images by considering the differences in both image intensity and gradient magnitude is a straightforward selection. In this paper, based on a diffeomorphic demons algorithm, we propose a chain-type diffeomorphic demons algorithm by combining the differences in both image intensity and gradient magnitude for medical image registration. Previous work had shown that the classic demons algorithm can be considered as an approximation of a second order gradient descent on the sum of the squared intensity differences. By optimizing the new dissimilarity criteria, we also present a set of new demons forces which were derived from the gradients of the image and gradient magnitude image. We show that, in controlled experiments, this advantage is confirmed, and yields a fast convergence.

Single-bubble boiling under Earth's and low gravity

NASA Astrophysics Data System (ADS)

Khusid, Boris; Elele, Ezinwa; Lei, Qian; Tang, John; Shen, Yueyang

2017-11-01

Miniaturization of electronic systems in terrestrial and space applications is challenged by a dramatic increase in the power dissipation per unit volume with the occurrence of localized hot spots where the heat flux is much higher than the average. Cooling by forced gas or liquid flow appears insufficient to remove high local heat fluxes. Boiling that involves evaporation of liquid in a hot spot and condensation of vapor in a cold region can remove a significantly larger amount of heat through the latent heat of vaporization than force-flow cooling can carry out. Traditional methods for enhancing boiling heat transfer in terrestrial and space applications focus on removal of bubbles from the heating surface. In contrast, we unexpectedly observed a new boiling regime of water under Earth's gravity and low gravity in which a bubble was pinned on a small heater up to 270°C and delivered a heat flux up to 1.2 MW/m2 that was as high as the critical heat flux in the classical boiling regime on Earth .Low gravity measurements conducted in parabolic flights in NASA Boeing 727. The heat flux in flight and Earth's experiments was found to rise linearly with increasing the heater temperature. We will discuss physical mechanisms underlying heat transfer in single-bubble boiling. The work supported by NASA Grants NNX12AM26G and NNX09AK06G.

Numerical simulation of linear fiction welding (LFW) processes

NASA Astrophysics Data System (ADS)

Fratini, L.; La Spisa, D.

2011-05-01

Solid state welding processes are becoming increasingly important due to a large number of advantages related to joining "unweldable" materials and in particular light weight alloys. Linear friction welding (LFW) has been used successfully to bond non-axisymmetric components of a range of materials including titanium alloys, steels, aluminum alloys, nickel, copper, and also dissimilar material combinations. The technique is useful in the research of quality of the joints and in reducing costs of components and parts of the aeronautic and automotive industries. LFW involves parts to be welded through the relative reciprocating motion of two components under an axial force. In such process the heat source is given by the frictional forces work decaying into heat determining a local softening of the material and proper bonding conditions due to both the temperature increase and the local pressure of the two edges to be welded. This paper is a comparative test between the numerical model in two dimensions, i.e. in plane strain conditions, and in three dimensions of a LFW process of AISI1045 steel specimens. It must be observed that the 3D model assures a faithful simulation of the actual threedimensional material flow, even if the two-dimensional simulation computational times are very short, a few hours instead of several ones as the 3D model. The obtained results were compared with experimental values found out in the scientific literature.

Topological dynamics of gyroscopic and Floquet lattices from Newton's laws

NASA Astrophysics Data System (ADS)

Lee, Ching Hua; Li, Guangjie; Jin, Guliuxin; Liu, Yuhan; Zhang, Xiao

2018-02-01

Despite intense interest in realizing topological phases across a variety of electronic, photonic, and mechanical platforms, the detailed microscopic origin of topological behavior often remains elusive. To bridge this conceptual gap, we show how hallmarks of topological modes—boundary localization and chirality—emerge from Newton's laws in mechanical topological systems. We first construct a gyroscopic lattice with analytically solvable edge modes, and show how the Lorentz and spring restoring forces conspire to support very robust "dangling bond" boundary modes. The chirality and locality of these modes intuitively emerges from microscopic balancing of restoring forces and cyclotron tendencies. Next, we introduce the highlight of this work, an experimentally realistic mechanical nonequilibrium (Floquet) Chern lattice driven by ac electromagnets. Through appropriate synchronization of the ac driving protocol, the Floquet lattice is "pushed around" by a rotating potential analogous to an object washed ashore by water waves. Besides hosting "dangling bond" chiral modes analogous to the gyroscopic boundary modes, our Floquet Chern lattice also supports peculiar half-period chiral modes with no static analog, i.e., analogs of anomalous Floquet Chern insulators edge modes. With key parameters controlled electronically, our setup has the advantage of being dynamically tunable for applications involving arbitrary Floquet modulations. The physical intuition gleaned from our two prototypical topological systems is applicable not just to arbitrarily complicated mechanical systems, but also photonic and electrical topological setups.

Seven Important Labor Force Trends.

ERIC Educational Resources Information Center

Bailey, John A.

1982-01-01

Presents statistics on the changing human resources mix in the labor force, which vocational counselors should be aware of. Trends include higher percentages of women working, and older men and married men leaving the work force. One result is an increasing number of persons are able to retire earlier. (JAC)

Force Generation upon T Cell Receptor Engagement

PubMed Central

Husson, Julien; Chemin, Karine; Bohineust, Armelle; Hivroz, Claire; Henry, Nelly

2011-01-01

T cells are major players of adaptive immune response in mammals. Recognition of an antigenic peptide in association with the major histocompatibility complex at the surface of an antigen presenting cell (APC) is a specific and sensitive process whose mechanism is not fully understood. The potential contribution of mechanical forces in the T cell activation process is increasingly debated, although these forces are scarcely defined and hold only limited experimental evidence. In this work, we have implemented a biomembrane force probe (BFP) setup and a model APC to explore the nature and the characteristics of the mechanical forces potentially generated upon engagement of the T cell receptor (TCR) and/or lymphocyte function-associated antigen-1 (LFA-1). We show that upon contact with a model APC coated with antibodies towards TCR-CD3, after a short latency, the T cell developed a timed sequence of pushing and pulling forces against its target. These processes were defined by their initial constant growth velocity and loading rate (force increase per unit of time). LFA-1 engagement together with TCR-CD3 reduced the growing speed during the pushing phase without triggering the same mechanical behavior when engaged alone. Intracellular Ca2+ concentration ([Ca2+]i) was monitored simultaneously to verify the cell commitment in the activation process. [Ca2+]i increased a few tens of seconds after the beginning of the pushing phase although no strong correlation appeared between the two events. The pushing phase was driven by actin polymerization. Tuning the BFP mechanical properties, we could show that the loading rate during the pulling phase increased with the target stiffness. This indicated that a mechanosensing mechanism is implemented in the early steps of the activation process. We provide here the first quantified description of force generation sequence upon local bidimensional engagement of TCR-CD3 and discuss its potential role in a T cell mechanically-regulated activation process. PMID:21572959

Force generation upon T cell receptor engagement.

PubMed

Husson, Julien; Chemin, Karine; Bohineust, Armelle; Hivroz, Claire; Henry, Nelly

2011-05-10

T cells are major players of adaptive immune response in mammals. Recognition of an antigenic peptide in association with the major histocompatibility complex at the surface of an antigen presenting cell (APC) is a specific and sensitive process whose mechanism is not fully understood. The potential contribution of mechanical forces in the T cell activation process is increasingly debated, although these forces are scarcely defined and hold only limited experimental evidence. In this work, we have implemented a biomembrane force probe (BFP) setup and a model APC to explore the nature and the characteristics of the mechanical forces potentially generated upon engagement of the T cell receptor (TCR) and/or lymphocyte function-associated antigen-1 (LFA-1). We show that upon contact with a model APC coated with antibodies towards TCR-CD3, after a short latency, the T cell developed a timed sequence of pushing and pulling forces against its target. These processes were defined by their initial constant growth velocity and loading rate (force increase per unit of time). LFA-1 engagement together with TCR-CD3 reduced the growing speed during the pushing phase without triggering the same mechanical behavior when engaged alone. Intracellular Ca(2+) concentration ([Ca(2+)](i)) was monitored simultaneously to verify the cell commitment in the activation process. [Ca(2+)](i) increased a few tens of seconds after the beginning of the pushing phase although no strong correlation appeared between the two events. The pushing phase was driven by actin polymerization. Tuning the BFP mechanical properties, we could show that the loading rate during the pulling phase increased with the target stiffness. This indicated that a mechanosensing mechanism is implemented in the early steps of the activation process. We provide here the first quantified description of force generation sequence upon local bidimensional engagement of TCR-CD3 and discuss its potential role in a T cell mechanically-regulated activation process.

Robotics and local fusion

NASA Astrophysics Data System (ADS)

Emmerman, Philip J.

2005-05-01

Teams of robots or mixed teams of warfighters and robots on reconnaissance and other missions can benefit greatly from a local fusion station. A local fusion station is defined here as a small mobile processor with interfaces to enable the ingestion of multiple heterogeneous sensor data and information streams, including blue force tracking data. These data streams are fused and integrated with contextual information (terrain features, weather, maps, dynamic background features, etc.), and displayed or processed to provide real time situational awareness to the robot controller or to the robots themselves. These blue and red force fusion applications remove redundancies, lessen ambiguities, correlate, aggregate, and integrate sensor information with context such as high resolution terrain. Applications such as safety, team behavior, asset control, training, pattern analysis, etc. can be generated or enhanced by these fusion stations. This local fusion station should also enable the interaction between these local units and a global information world.

Spatial Localization in Dissipative Systems

NASA Astrophysics Data System (ADS)

Knobloch, E.

2015-03-01

Spatial localization is a common feature of physical systems, occurring in both conservative and dissipative systems. This article reviews the theoretical foundations of our understanding of spatial localization in forced dissipative systems, from both a mathematical point of view and a physics perspective. It explains the origin of the large multiplicity of simultaneously stable spatially localized states present in a parameter region called the pinning region and its relation to the notion of homoclinic snaking. The localized states are described as bound states of fronts, and the notions of front pinning, self-pinning, and depinning are emphasized. Both one-dimensional and two-dimensional systems are discussed, and the reasons behind the differences in behavior between dissipative systems with conserved and nonconserved dynamics are explained. The insights gained are specific to forced dissipative systems and are illustrated here using examples drawn from fluid mechanics (convection and shear flows) and a simple model of crystallization.

Gender comparison of psychophysical forces, cardiopulmonary, and muscle metabolic responses during a simulated cart pushing task.

PubMed

Maikala, Rammohan V; Ciriello, Vincent M; Dempsey, Patrick G; O'Brien, Niall V

2010-10-01

The purpose was to compare psychophysiological responses between healthy male and female workers during dynamic pushing. Using a psychophysical approach, 27 participants chose an acceptable force that they could push over a 7.6m distance at a frequency of 1 push per min on a treadmill. On a separate day, cardiopulmonary (e.g., whole-body oxygen uptake, heart rate, ventilation volume) and muscle metabolic measurements (change in muscle blood volume [ΔtHb] and Tissue Oxygenation Index [TOI]) from the right and left gastrocnemius muscles were collected simultaneously while participants pushed the previously chosen acceptable force on the treadmill at a similar frequency and distance for 2h. Results showed no significant difference between men and women for integrated force exerted on the instrumented treadmill handle and cardiopulmonary responses. In contrast, women demonstrated 45.7% lower ΔtHb but 3.6% higher TOI in the gastrocnemius region as compared to men, suggesting a lower hemoglobin concentration in women and high venous oxygen saturation during pushing. When ΔtHb and TOI were corrected for both body mass and pushing force, the disparity in gender was retained, implying an increased muscle oxygen saturation per force development in women than men during pushing. In the left gastrocnemius region, ΔtHb was 60% lower and TOI was 5.7% higher in women than men, suggesting an uneven muscle loading during pushing. Overall, the gender similarity in cardiopulmonary responses versus disparity in muscle metabolic responses suggest the importance of evaluating human performance during physical work at both whole-body and localized muscle levels. Copyright © 2010 Elsevier B.V. All rights reserved.

Spectral element simulation of precession driven flows in the outer cores of spheroidal planets

NASA Astrophysics Data System (ADS)

Vormann, Jan; Hansen, Ulrich

2015-04-01

A common feature of the planets in the solar system is the precession of the rotation axes, driven by the gravitational influence of another body (e.g. the Earth's moon). In a precessing body, the rotation axis itself is rotating around another axis, describing a cone during one precession period. Similar to the coriolis and centrifugal force appearing from the transformation to a rotating system, the addition of precession adds another term to the Navier-Stokes equation, the so called Poincaré force. The main geophysical motivation in studying precession driven flows comes from their ability to act as magnetohydrodynamic dynamos in planets and moons. Precession may either act as the only driving force or operate together with other forces such as thermochemical convection. One of the challenges in direct numerical simulations of such flows lies in the spheroidal shape of the fluid volume, which should not be neglected since it contributes an additional forcing trough pressure torques. Codes developed for the simulation of flows in spheres mostly use efficient global spectral algorithms that converge fast, but lack geometric flexibility, while local methods are usable in more complex shapes, but often lack high accuracy. We therefore adapted the spectral element code Nek5000, developed at Argonne National Laboratory, to the problem. The spectral element method is capable of solving for the flow in arbitrary geometries while still offering spectral convergence. We present first results for the simulation of a purely hydrodynamic, precession-driven flow in a spheroid with no-slip boundaries and an inner core. The driving by the Poincaré force is in a range where theoretical work predicts multiple solutions for a laminar flow. Our simulations indicate a transition to turbulent flows for Ekman numbers of 10-6 and lower.

The global warming in the North Atlantic Sector and the role of the ocean

NASA Astrophysics Data System (ADS)

Hand, R.; Keenlyside, N. S.; Greatbatch, R. J.; Omrani, N. E.

2014-12-01

This work presents an analysis of North Atlantic ocean-atmosphere interaction in a warming climate, based on a long-term earth system model experiment forced by the RCP 8.5 scenario, the strongest greenhouse gas forcing used in the climate projections for the 5th Assessement report of the Intergovernmental Panel on Climate Change). In addition to a global increase in SSTs as a direct response to the radiative forcing, the model shows a distinct change of the local sea surface temperature (SST hereafter) patterns in the Gulf Stream region: The SST front moves northward by several hundred kilometers, likely as a response of the wind-driven part of the oceanic surface circulation, and becomes more zonal. As a consequence of a massive slowdown of the Atlantic Meridional Overturning Circulation, the northeast North Atlantic only shows a moderate warming compared to the rest of the ocean. The feedback of these changes on the atmosphere was studied in a set of sensitivity experiments based on the SST climatology of the coupled runs. The set consists of a control run based on the historical run, a run using the full SST from the coupled RCP 8.5 run and two runs, where the SST signal was deconstructed into a homogenous mean warming part and a local pattern change. In the region of the precipitation maximum in the historical run the future scenario shows an increase of absolute SSTs, but a significant decrease in local precipitation, low-level convergence and upward motion. Since warmer SSTs usually cause the opposite, this indicates that the local response in that region is connected to the (with respect to the historical run) weakened SST gradients rather than to the absolute SST. Consistently, the model shows enhanced precipitation north of this region, where the SST gradients are enhanced. However, the signal restricts to the low and mid-troposphere and does not reach the higher model levels. There is little evidence for a large-scale response to the changes in the Gulf Stream region; instead, the large scale signal is mainly controlled by the warmer background state and the AMOC slowdown and influenced by tropical SSTs. In a warmer climate the same change in SST gradient has a stronger effect on precipitation and the model produces a slightly enhanced North Atlantic storm track.

The Effects of Vibration and Muscle Fatigue on Trunk Sensorimotor Control in Low Back Pain Patients

PubMed Central

Abboud, Jacques; Nougarou, François; Normand, Martin C.

2015-01-01

Introduction Changes in sensorimotor function and increased trunk muscle fatigability have been identified in patients with chronic low back pain (cLBP). This study assessed the control of trunk force production in conditions with and without local erector spinae muscle vibration and evaluated the influence of muscle fatigue on trunk sensorimotor control. Methods Twenty non-specific cLBP patients and 20 healthy participants were asked to perform submaximal isometric trunk extension torque with and without local vibration stimulation, before and after a trunk extensor muscle fatigue protocol. Constant error (CE), variable error (VE) as well as absolute error (AE) in peak torque were computed and compared across conditions. Trunk extensor muscle activation during isometric contractions and during the fatigue protocol was measured using surface electromyography (sEMG). Results Force reproduction accuracy of the trunk was significantly lower in the patient group (CE = 9.81 ± 2.23 Nm; AE = 18.16 ± 3.97 Nm) than in healthy participants (CE = 4.44 ± 1.68 Nm; AE = 12.23 ± 2.44 Nm). Local erector spinae vibration induced a significant reduction in CE (4.33 ± 2.14 Nm) and AE (13.71 ± 3.45 Nm) mean scores in the patient group. Healthy participants conversely showed a significant increase in CE (8.17 ± 2.10 Nm) and AE (16.29 ± 2.82 Nm) mean scores under vibration conditions. The fatigue protocol induced erector spinae muscle fatigue as illustrated by a significant decrease in sEMG median time-frequency slopes. Following the fatigue protocol, patients with cLBP showed significant decrease in sEMG root mean square activity at L4-5 level and responded in similar manner with and without vibration stimulation in regard to CE mean scores. Conclusions Patients with cLBP have a less accurate force reproduction sense than healthy participants. Local muscle vibration led to significant trunk neuromuscular control improvements in the cLBP patients before and after a muscle fatigue protocol. Muscle vibration stimulation during motor control exercises is likely to influence motor adaptation and could be considered in the treatment of cLBP. Further work is needed to clearly identify at what levels of the sensorimotor system these gains are achievable. PMID:26308725

The Effects of Vibration and Muscle Fatigue on Trunk Sensorimotor Control in Low Back Pain Patients.

PubMed

Boucher, Jean-Alexandre; Abboud, Jacques; Nougarou, François; Normand, Martin C; Descarreaux, Martin

2015-01-01

Changes in sensorimotor function and increased trunk muscle fatigability have been identified in patients with chronic low back pain (cLBP). This study assessed the control of trunk force production in conditions with and without local erector spinae muscle vibration and evaluated the influence of muscle fatigue on trunk sensorimotor control. Twenty non-specific cLBP patients and 20 healthy participants were asked to perform submaximal isometric trunk extension torque with and without local vibration stimulation, before and after a trunk extensor muscle fatigue protocol. Constant error (CE), variable error (VE) as well as absolute error (AE) in peak torque were computed and compared across conditions. Trunk extensor muscle activation during isometric contractions and during the fatigue protocol was measured using surface electromyography (sEMG). Force reproduction accuracy of the trunk was significantly lower in the patient group (CE = 9.81 ± 2.23 Nm; AE = 18.16 ± 3.97 Nm) than in healthy participants (CE = 4.44 ± 1.68 Nm; AE = 12.23 ± 2.44 Nm). Local erector spinae vibration induced a significant reduction in CE (4.33 ± 2.14 Nm) and AE (13.71 ± 3.45 Nm) mean scores in the patient group. Healthy participants conversely showed a significant increase in CE (8.17 ± 2.10 Nm) and AE (16.29 ± 2.82 Nm) mean scores under vibration conditions. The fatigue protocol induced erector spinae muscle fatigue as illustrated by a significant decrease in sEMG median time-frequency slopes. Following the fatigue protocol, patients with cLBP showed significant decrease in sEMG root mean square activity at L4-5 level and responded in similar manner with and without vibration stimulation in regard to CE mean scores. Patients with cLBP have a less accurate force reproduction sense than healthy participants. Local muscle vibration led to significant trunk neuromuscular control improvements in the cLBP patients before and after a muscle fatigue protocol. Muscle vibration stimulation during motor control exercises is likely to influence motor adaptation and could be considered in the treatment of cLBP. Further work is needed to clearly identify at what levels of the sensorimotor system these gains are achievable.

Progress toward national estimates of police use of force

PubMed Central

Garner, Joel H.; Malega, Ronald W.; Maxwell, Christopher D.

2018-01-01

This research builds on three decades of effort to produce national estimates of the amount and rate of force used by law enforcement officers in the United States. Prior efforts to produce national estimates have suffered from poor and inconsistent measurements of force, small and unrepresentative samples, low survey and/or item response rates, and disparate reporting of rates of force. The present study employs data from a nationally representative survey of state and local law enforcement agencies that has a high survey response rate as well as a relatively high rate of reporting uses of force. Using data on arrests for violent offenses and the number of sworn officers to impute missing data on uses of force, we estimate a total of 337,590 use of physical force incidents among State and local law enforcement agencies during 2012 with a 95 percent confidence interval of +/- 10,470 incidents or +/- 3.1 percent. This article reports the extent to which the number and rate of force incidents vary by the type and size of law enforcement agencies. Our findings demonstrate the willingness of a large proportion of law enforcement agencies to voluntarily report the amount of force used by their officers and the relative strengths and weaknesses of the Law Enforcement Management and Administrative Statistics (LEMAS) program to produce nationally representative information about police behavior. PMID:29447295

Modeling physical vapor deposition of energetic materials

DOE PAGES

Shirvan, Koroush; Forrest, Eric C.

2018-03-28

Morphology and microstructure of organic explosive films formed using physical vapor deposition (PVD) processes strongly depends on local surface temperature during deposition. Currently, there is no accurate means of quantifying the local surface temperature during PVD processes in the deposition chambers. This study focuses on using a multiphysics computational fluid dynamics tool, STARCCM+, to simulate pentaerythritol tetranitrate (PETN) deposition. The PETN vapor and solid phase were simulated using the volume of fluid method and its deposition in the vacuum chamber on spinning silicon wafers was modeled. The model also included the spinning copper cooling block where the wafers are placedmore » along with the chiller operating with forced convection refrigerant. Implicit time-dependent simulations in two- and three-dimensional were performed to derive insights in the governing physics for PETN thin film formation. PETN is deposited at the rate of 14 nm/s at 142.9 °C on a wafer with an initial temperature of 22 °C. The deposition of PETN on the wafers was calculated at an assumed heat transfer coefficient (HTC) of 400 W/m 2 K. This HTC proved to be the most sensitive parameter in determining the local surface temperature during deposition. Previous experimental work found noticeable microstructural changes with 0.5 mm fused silica wafers in place of silicon during the PETN deposition. This work showed that fused silica slows initial wafer cool down and results in ~10 °C difference for the surface temperature at 500 μm PETN film thickness. It was also found that the deposition surface temperature is insensitive to the cooling power of the copper block due to the copper block's very large heat capacity and thermal conductivity relative to the heat input from the PVD process. Future work should incorporate the addition of local stress during PETN deposition. Lastly, based on simulation results, it is also recommended to investigate the impact of wafer surface energy on the PETN microstructure and morphology formation.« less

Modeling physical vapor deposition of energetic materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shirvan, Koroush; Forrest, Eric C.

Morphology and microstructure of organic explosive films formed using physical vapor deposition (PVD) processes strongly depends on local surface temperature during deposition. Currently, there is no accurate means of quantifying the local surface temperature during PVD processes in the deposition chambers. This study focuses on using a multiphysics computational fluid dynamics tool, STARCCM+, to simulate pentaerythritol tetranitrate (PETN) deposition. The PETN vapor and solid phase were simulated using the volume of fluid method and its deposition in the vacuum chamber on spinning silicon wafers was modeled. The model also included the spinning copper cooling block where the wafers are placedmore » along with the chiller operating with forced convection refrigerant. Implicit time-dependent simulations in two- and three-dimensional were performed to derive insights in the governing physics for PETN thin film formation. PETN is deposited at the rate of 14 nm/s at 142.9 °C on a wafer with an initial temperature of 22 °C. The deposition of PETN on the wafers was calculated at an assumed heat transfer coefficient (HTC) of 400 W/m 2 K. This HTC proved to be the most sensitive parameter in determining the local surface temperature during deposition. Previous experimental work found noticeable microstructural changes with 0.5 mm fused silica wafers in place of silicon during the PETN deposition. This work showed that fused silica slows initial wafer cool down and results in ~10 °C difference for the surface temperature at 500 μm PETN film thickness. It was also found that the deposition surface temperature is insensitive to the cooling power of the copper block due to the copper block's very large heat capacity and thermal conductivity relative to the heat input from the PVD process. Future work should incorporate the addition of local stress during PETN deposition. Lastly, based on simulation results, it is also recommended to investigate the impact of wafer surface energy on the PETN microstructure and morphology formation.« less

What is the prevalence of and associations with forced labour experiences among male migrants from Dolakha, Nepal? Findings from a cross-sectional study of returnee migrants

PubMed Central

Mak, Joelle; Abramsky, Tanya; Sijapati, Bandita; Kiss, Ligia; Zimmerman, Cathy

2017-01-01

Objectives Growing numbers of people are migrating outside their country for work, and many experience precarious conditions, which have been linked to poor physical and mental health. While international dialogue on human trafficking, forced labour and slavery increases, prevalence data of such experiences remain limited. Methods Men from Dolakha, Nepal, who had ever migrated outside of Nepal for work were interviewed on their experiences, from predeparture to return (n=194). Forced labour was assessed among those who returned within the past 10 years (n=140) using the International Labour Organization's forced labour dimensions: (1) unfree recruitment; (2) work and life under duress; and (3) impossibility to leave employer. Forced labour is positive if any one of the dimensions is positive. Results Participants had worked in India (34%), Malaysia (34%) and the Gulf Cooperation Council countries (29%), working in factories (29%), as labourers/porters (15%) or in skilled employment (12%). Among more recent returnees (n=140), 44% experienced unfree recruitment, 71% work and life under duress and 14% impossibility to leave employer. Overall, 73% experienced forced labour during their most recent labour migration. Forced labour was more prevalent among those who had taken loans for their migration (PR 1.23) and slightly less prevalent among those who had migrated more than once (PR 0.87); however the proportion of those who experienced forced labour was still high (67%). Age, destination and duration of stay were associated with only certain dimensions of forced labour. Conclusion Forced labour experiences were common during recruitment and at destination. Migrant workers need better advice on assessing agencies and brokers, and on accessing services at destinations. As labour migration from Nepal is not likely to reduce in the near future, interventions and policies at both source and destinations need to better address the challenges migrants face so they can achieve safer outcomes. PMID:28801409

Local Muscle Metabolic Demand Induced by Neuromuscular Electrical Stimulation and Voluntary Contractions at Different Force Levels: A NIRS Study.

PubMed

Muthalib, Makii; Kerr, Graham; Nosaka, Kazunori; Perrey, Stephane

2016-06-13

Functional Muscle metabolic demand during contractions evoked by neuromuscular electrical stimulation (NMES) has been consistently documented to be greater than voluntary contractions (VOL) at the same force level (10-50% maximal voluntary contraction-MVC). However, we have shown using a near-infrared spectroscopy (NIRS) technique that local muscle metabolic demand is similar between NMES and VOL performed at MVC levels, thus controversy exists. This study therefore compared biceps brachii muscle metabolic demand (tissue oxygenation index-TOI and total hemoglobin volume-tHb) during a 10s isometric contraction of the elbow flexors between NMES (stimulation frequency of 30Hz and current level to evoke 30% MVC) and VOL at 30% MVC (VOL-30%MVC) and MVC (VOL-MVC) level in 8 healthy men (23-33-y). Greater changes in TOI and tHb induced by NMES than VOL-30%MVC confirm previous studies of a greater local metabolic demand for NMES than VOL at the same force level. The same TOI and tHb changes for NMES and VOL-MVC suggest that local muscle metabolic demand and intramuscular pressure were similar between conditions. In conclusion, these findings indicate that NMES induce a similar local muscle metabolic demand as that of maximal VOL.

Local Muscle Metabolic Demand Induced by Neuromuscular Electrical Stimulation and Voluntary Contractions at Different Force Levels: A NIRS Study

PubMed Central

Muthalib, Makii; Kerr, Graham; Nosaka, Kazunori; Perrey, Stephane

2016-01-01

Functional Muscle metabolic demand during contractions evoked by neuromuscular electrical stimulation (NMES) has been consistently documented to be greater than voluntary contractions (VOL) at the same force level (10-50% maximal voluntary contraction-MVC). However, we have shown using a near-infrared spectroscopy (NIRS) technique that local muscle metabolic demand is similar between NMES and VOL performed at MVC levels, thus controversy exists. This study therefore compared biceps brachii muscle metabolic demand (tissue oxygenation index-TOI and total hemoglobin volume-tHb) during a 10s isometric contraction of the elbow flexors between NMES (stimulation frequency of 30Hz and current level to evoke 30% MVC) and VOL at 30% MVC (VOL-30%MVC) and MVC (VOL-MVC) level in 8 healthy men (23-33-y). Greater changes in TOI and tHb induced by NMES than VOL-30%MVC confirm previous studies of a greater local metabolic demand for NMES than VOL at the same force level. The same TOI and tHb changes for NMES and VOL-MVC suggest that local muscle metabolic demand and intramuscular pressure were similar between conditions. In conclusion, these findings indicate that NMES induce a similar local muscle metabolic demand as that of maximal VOL. PMID:27478574

Work/Family Interactions: Trends and Applications.

ERIC Educational Resources Information Center

Engelbrecht, JoAnn D.; Nies, Joyce I.

1988-01-01

The authors discuss five trends and how family life educators can address them. The trends are (1) women's labor force participation, (2) growth of the service sector, (3) recognition that work and family life affect each other, (4) space sharing by work and family life, and (5) aging of the work force. (CH)

Traction force microscopy in rapidly moving cells reveals separate roles for ROCK and MLCK in the mechanics of retraction.

PubMed

Morin, Timothy R; Ghassem-Zadeh, Sean A; Lee, Juliet

2014-08-15

Retraction is a major rate-limiting step in cell motility, particularly in slow moving cell types that form large stable adhesions. Myosin II dependent contractile forces are thought to facilitate detachment by physically pulling up the rear edge. However, retraction can occur in the absence of myosin II activity in cell types that form small labile adhesions. To investigate the role of contractile force generation in retraction, we performed traction force microscopy during the movement of fish epithelial keratocytes. By correlating changes in local traction stress at the rear with the area retracted, we identified four distinct modes of retraction. "Recoil" retractions are preceded by a rise in local traction stress, while rear edge is temporarily stuck, followed by a sharp drop in traction stress upon detachment. This retraction type was most common in cells generating high average traction stress. In "pull" type retractions local traction stress and area retracted increase concomitantly. This was the predominant type of retraction in keratocytes and was observed mostly in cells generating low average traction stress. "Continuous" type retractions occur without any detectable change in traction stress, and are seen in cells generating low average traction stress. In contrast, to many other cell types, "release" type retractions occur in keratocytes following a decrease in local traction stress. Our identification of distinct modes of retraction suggests that contractile forces may play different roles in detachment that are related to rear adhesion strength. To determine how the regulation of contractility via MLCK or Rho kinase contributes to the mechanics of detachment, inhibitors were used to block or augment these pathways. Modulation of MLCK activity led to the most rapid change in local traction stress suggesting its importance in regulating attachment strength. Surprisingly, Rho kinase was not required for detachment, but was essential for localizing retraction to the rear. We suggest that in keratocytes MLCK and Rho kinase play distinct, complementary roles in the respective temporal and spatial control of rear detachment that is essential for maintaining rapid motility. Copyright © 2014 Elsevier Inc. All rights reserved.

A Report of the Child Labor Task Force.

ERIC Educational Resources Information Center

Oregon State Bureau of Labor and Industry, Portland.

A task force studied youth work and its impact on the health, education, and safety of 16- and 17-year-olds. The study covered such issues as the following: effects of work on school performance, work's physical and psychological effects on young people, the effects work can have on young people's preparation for lifelong work, and what steps can…

Work-Family Spillover and Daily Reports of Work and Family Stress in the Adult Labor Force.

ERIC Educational Resources Information Center

Grzywacz, Joseph G.; Almeida, David M.; McDonald, Daniel A.

2002-01-01

Data from two affiliated national surveys were used to examine distribution of work-family spillover among working adults. Analyses testing family life course hypotheses indicated self-reported negative and positive spillover between work and family were not randomly distributed within the labor force. Age was found to have a persistent…

PSD microscopy: a new technique for adaptive local scanning of microscale objects.

PubMed

Rahimi, Mehdi; Shen, Yantao

2017-01-01

A position-sensitive detector/device (PSD) is a sensor that is capable of tracking the location of a laser beam on its surface. PSDs are used in many scientific instruments and technical applications including but not limited to atomic force microscopy, human eye movement monitoring, mirrors or machine tool alignment, vibration analysis, beam position control and so on. This work intends to propose a new application using the PSD. That is a new microscopy system called scanning PSD microscopy. The working mechanism is about putting an object on the surface of the PSD and fast scanning its area with a laser beam. To achieve a high degree of accuracy and precision, a reliable framework was designed using the PSD. In this work, we first tried to improve the PSD reading and its measurement performance. This was done by minimizing the effects of noise, distortion and other disturbing parameters. After achieving a high degree of confidence, the microscopy system can be implemented based on the improved PSD measurement performance. Later to improve the scanning efficiency, we developed an adaptive local scanning system to scan the whole area of the PSD in a short matter of time. It was validated that our comprehensive and adaptive local scanning method can shorten the scanning time in order of hundreds of times in comparison with the traditional raster scanning without losing any important information about the scanned 2D objects. Methods are also introduced to scan very complicated objects with bifurcations and crossings. By incorporating all these methods, the new microscopy system is capable of scanning very complicated objects in the matter of a few seconds with a resolution that is in order of a few micrometers.