Long-term observations of tropospheric ozone: GAW Measurement Guidelines

NASA Astrophysics Data System (ADS)

Tarasova, Oksana; Galbally, Ian E.; Schultz, Martin G.

2013-04-01

The Global Atmosphere Watch (GAW) Programme of the World Meteorological Organization (WMO) coordinates long-term observations of the chemical composition and physical properties of the atmosphere which are relevant for understanding of atmospheric chemistry and climate change. Atmospheric observations of reactive gases (tropospheric ozone, carbon monoxide, volatile organic compounds and nitrogen oxides) coordinated by the GAW Programme complement local and regional scale air quality monitoring efforts. As part of the GAW quality assurance (QA) system detailed measurement guidelines for atmospheric trace species are developed by international expert teams at irregular intervals. The most recent report focuses on continuous in-situ measurements of ozone in the troposphere, performed in particular at continental or island sites with altitudes ranging from sea level to mountain tops. Data Quality Objectives (DQOs) are defined for different applications of the data (e.g. trend analysis and verification of global model forecasts). These DQOs include a thorough discussion of the tolerable level of measurement uncertainty and data completeness. The guidelines present the best practices and practical arrangements adopted by the GAW Programme in order to enable the GAW station network to approach or achieve the defined tropospheric ozone DQOs. The document includes information on the selection of station and measurement locations, required skills and training of staff, recommendations on the measurement technique and the necessary equipment to perform highest quality measurements, rules for conducting the measurements, preparing the data and archiving them, and more. Much emphasis is given to discussions about how to ensure the quality of the data through tracing calibrations back to primary standards, proper calibration and data analysis, etc. In the GAW Programme the QA system is implemented through Central Facilities (Central Calibration Laboratories, World and Regional

A mechanism of midlatitude noontime foE long-term variations inferred from European observations

NASA Astrophysics Data System (ADS)

Mikhailov, A. V.; Perrone, L.; Nusinov, A. A.

2017-04-01

Manually scaled June noontime monthly median foE values at three European stations Rome, Juliusruh, and Slough/Chilton were used to understand the mechanism of foE long-term variations. The 11 year running mean smoothed foE manifests long-term (for some solar cycles) variations with the rising phase at the end of 1960-1985 and the falling phase after 1985. A close relationship (even in details) between (foEave)11y and (R12)11y variations with the correlation coefficient of 0.996 (absolutely significant according to Fisher F criterion) suggests that the Sun is the source of these (foEave)11y long-term variations. After removing solar activity long-term variations the residual (foEave)11y trend is very small ( 0.029% per decade) being absolutely insignificant. This means that all (foEave)11y variations are removed with one solar activity index, (R12)11y, i.e., this means that long-term variations are fully controlled by solar activity. Theory of midlatitude daytime E region tells us that long-term variations of solar EUV in two lines λ = 977 Å (CIII) and λ = 1025.7 Å (HLyβ) and X-ray radiation with λ < 100 Å (both manifesting the same long-term variations with the rising phase at the end of 1960-1985 and the falling phase after 1985) are responsible for the observed (foEave)11y variations. Therefore, the observed daytime midlatitude foE long-term variations have a natural (not anthropogenic) origin related to long-term variations of solar activity. No peculiarities in relation with the last deep solar minimum in 2008-2009 have been revealed.

Nitrous Oxide Production at a Fully Covered Wastewater Treatment Plant: Results of a Long-Term Online Monitoring Campaign.

PubMed

Kosonen, Heta; Heinonen, Mari; Mikola, Anna; Haimi, Henri; Mulas, Michela; Corona, Francesco; Vahala, Riku

2016-06-07

The nitrous oxide emissions of the Viikinmäki wastewater treatment plant were measured in a 12 month online monitoring campaign. The measurements, which were conducted with a continuous gas analyzer, covered all of the unit operations of the advanced wastewater-treatment process. The relation between the nitrous oxide emissions and certain process parameters, such as the wastewater temperature, influent biological oxygen demand, and ammonium nitrogen load, was investigated by applying online data obtained from the process-control system at 1 min intervals. Although seasonal variations in the measured nitrous oxide emissions were remarkable, the measurement data indicated no clear relationship between these emissions and seasonal changes in the wastewater temperature. The diurnal variations of the nitrous oxide emissions did, however, strongly correlate with the alternation of the influent biological oxygen demand and ammonium nitrogen load to the aerated zones of the activated sludge process. Overall, the annual nitrous oxide emissions of 168 g/PE/year and the emission factor of 1.9% of the influent nitrogen load are in the high range of values reported in the literature but in very good agreement with the results of other long-term online monitoring campaigns implemented at full-scale wastewater-treatment plants.

Automated Long - Term Scheduling for the SOFIA Airborne Observatory

NASA Technical Reports Server (NTRS)

Civeit, Thomas

2013-01-01

The NASA Stratospheric Observatory for Infrared Astronomy (SOFIA) is a joint US/German project to develop and operate a gyro-stabilized 2.5-meter telescope in a Boeing 747SP. SOFIA's first science observations were made in December 2010. During 2011, SOFIA accomplished 30 flights in the "Early Science" program as well as a deployment to Germany. The new observing period, known as Cycle 1, is scheduled to begin in 2012. It includes 46 science flights grouped in four multi-week observing campaigns spread through a 13-month span. Automation of the flight scheduling process offers a major challenge to the SOFIA mission operations. First because it is needed to mitigate its relatively high cost per unit observing time compared to space-borne missions. Second because automated scheduling techniques available for ground-based and space-based telescopes are inappropriate for an airborne observatory. Although serious attempts have been made in the past to solve part of the problem, until recently mission operations staff was still manually scheduling flights. We present in this paper a new automated solution for generating SOFIA long-term schedules that will be used in operations from the Cycle 1 observing period. We describe the constraints that should be satisfied to solve the SOFIA scheduling problem in the context of real operations. We establish key formulas required to efficiently calculate the aircraft course over ground when evaluating flight schedules. We describe the foundations of the SOFIA long-term scheduler, the constraint representation, and the random search based algorithm that generates observation and instrument schedules. Finally, we report on how the new long-term scheduler has been used in operations to date.

The PACA Project Observing Campaigns: From Comets to the Sun

NASA Astrophysics Data System (ADS)

Yanamandra-Fisher, Padma A.; PACA Project

2017-10-01

The Pro-Am Collaborative Astronomy (PACA) project evolved from the observational campaign of C/2012 S1 or C/ISON in 2013, and has expanded to pro-am observing campaigns of planets, polarimetric exploration and recently, polarization of the inner solar corona during the 2017 US Continental Total Solar Eclipse (TSE). The evolving need for individual customized observing campaigns has been incorporated into the evolution of PACA portal: supporting observing campaigns of current comets, legacy data, historical comets, planets, solar corona, interconnected with social media and a set of shareable documents addressing observational strategies; consistent standards for data; data access, use, and storage, to align with the needs of professional observers. Given the volume of data generated for each campaign, new ways of rapid data analysis, mining access and storage are needed. Several interesting results emerged from the synergistic inclusion of both social media and amateur astronomers: (1) the establishment of a network of astronomers and related professionals, that can be galvanized into action on short notice to support observing campaigns; (2) assist in various science investigations pertinent to the campaign; (3) provide an alert-sounding mechanism should the need arise; (4) immediate outreach and dissemination of results via our media/blogger members; (5) provide a forum for discussions between the imagers and modelers to help strategize the observing campaign for maximum benefit. Some recent PACA campaigns of note are: C/2013 A1 (C/SidingSpring) ; 67P/Churyumov-Gerasimenko (CG), target for ESA/Rosetta mission; PACA_Jupiter (and for other planets Mars, Saturn, Uranus and Neptune); polarimetry and current campaign PACA_PolNet, a multi-site polarimetric network to be implemented in August 2017, in partnership with the project Citizen CATE. I will highlight key aspects of various PACA campaigns, especially the current PACA_PolNet for the 2017 Total Solar Eclipse and

Scientific Understanding from Long Term Observations: Insights from the Long Term Ecological Research (LTER) Program

NASA Astrophysics Data System (ADS)

Gosz, J.

2001-12-01

The network dedicated to Long Term Ecological Research (LTER) in the United States has grown to 24 sites since it was formed in 1980. Long-term research and monitoring are performed on parameters thatare basic to all ecosystems and are required to understand patterns, processes, and relationship to change. Collectively, the sites in the LTER Network provide opportunities to contrast marine, coastal, and continental regions, the full range of climatic gradients existing in North America, and aquatic and terrestrial habitats in a range of ecosystem types. The combination of common core areas and long-term research and monitoring in many habitats have allowed unprecedented abilities to understand and compare complex temporal and spatial dynamics associated with issues like climate change, effects of pollution, biodiversity and landuse. For example, McMurdo Dry Valley in the Antarctic has demonstrated an increase in glacier mass since 1993 which coincides with a period of cooler than normal summers and more than average snowfall. In contrast, the Bonanza Creek and Toolik Lake sites in Alaska have recorded a warming period unprecedented in the past 200 years. Nitrogen deposition effects have been identified through long-term watershed studies on biogeochemical cycles, especially at Coweeta Hydrological Lab, Harvard Forest, and the Hubbard Brook Experimental Forest. In aquatic systems, such as the Northern Temperate Lakes site, long-term data revealed time lags in effects of invaders and disturbance on lake communities. Biological recovery from an effect such as lake acidification was shown to lag behind chemical recovery. The long-term changes documented over 2 decades have been instrumental in influencing management practices in many of the LTER areas. In Puerto Rico, the Luquillo LTER demonstrated that dams obstruct migrations of fish and freshwater shrimp and water abstraction at low flows can completely obliterate downstream migration of juveniles and damage

2014 Southern δ-Aquariid observing campaign - carried out from Crete

NASA Astrophysics Data System (ADS)

Weiland, T.

2016-01-01

With a peak ZHR of 15-20 at the end of July, the Southern δ-Aquariids rank as a major annual shower, but observation is often neglected in favor of the much more active Perseids of August, mainly as a consequence of their southerly radiant, which makes the stream a prominent target from low latitudes and the southern hemisphere. The extended activity period of more than a month, lacking a distinctive peak, and the paucity of bright meteors does not enhance interest of most observers, either. Nevertheless, one has not to go too far south in order to monitor the stream properly to gain scientific results. The Greek island of Crete, at the southernmost tip of Europe, is such a place, offering sufficiently dark skies and a 90 % probability of clear weather in July and August. Encouraged by a New Moon on July 26th an eight-night-long visual observing campaign was carried out in 2014. As a consequence, I managed to record nearly 250 Southern δ-Aquariids within 40 hours of effective observing time. An impression of the campaign together with a summary of the results is presented.

Supporting observation campaigns with high resolution modeling

NASA Astrophysics Data System (ADS)

Klocke, Daniel; Brueck, Matthias; Voigt, Aiko

2017-04-01

High resolution simulation in support of measurement campaigns offers a promising and emerging way to create large-scale context for small-scale observations of clouds and precipitation processes. As these simulation include the coupling of measured small-scale processes with the circulation, they also help to integrate the research communities from modeling and observations and allow for detailed model evaluations against dedicated observations. In connection with the measurement campaign NARVAL (August 2016 and December 2013) simulations with a grid-spacing of 2.5 km for the tropical Atlantic region (9000x3300 km), with local refinement to 1.2 km for the western part of the domain, were performed using the icosahedral non-hydrostatic (ICON) general circulation model. These simulations are again used to drive large eddy resolving simulations with the same model for selected days in the high definition clouds and precipitation for advancing climate prediction (HD(CP)2) project. The simulations are presented with the focus on selected results showing the benefit for the scientific communities doing atmospheric measurements and numerical modeling of climate and weather. Additionally, an outlook will be given on how similar simulations will support the NAWDEX measurement campaign in the North Atlantic and AC3 measurement campaign in the Arctic.

Third world campaign.

PubMed

Culpin, P

1988-10-22

Your readers may be interested in knowing that VSO will be holding a publicity campaign in Scotland in November and December. The campaign is a chance for people to come and talk to us about the opportunities available to them to work in Third World countries. We have a wide range of interesting and challenging jobs in long-term development in health work.

Deteriorating water clarity in shallow waters: Evidence from long term MODIS and in-situ observations

NASA Astrophysics Data System (ADS)

Shi, Kun; Zhang, Yunlin; Zhu, Guangwei; Qin, Boqiang; Pan, Delu

2018-06-01

Water clarity (Secchi disk depth: SDD), as a proxy of water transparency, provides important information on the light availability to the water or lake ecosystem. Shallow lakes have been experienced dramatic environmental and climatic change. This study demonstrated using combination of long-term MODIS and in-situ measurements to track the dynamics of SDD with these environmental and climate changes in shallow water environments. We selected a typical turbid shallow Lake Taihu as our case study. Based on MODIS-Aqua data, an empirical model for estimating SDD was developed and validated. Subsequently, we employed the proposed model to derive the spatial and temporal SDD distribution patterns of Lake Taihu from 2003 to 2015. Combining MODIS-derived SDD time series of 2003-2015 and long-term in-situ SDD observations dated back to 1993, we elucidated SDD long-term variation trends and driving mechanism. Deteriorating water clarity from the long-term SDD observations indicated that Lake Taihu became more and more turbid and water quality was decreasing. Increasing in cyanobacterial bloom area, as a result of decreasing in wind speed and eutrophication, may partially be responsible for the decreasing trend. A predicted future decrease in the wind speed in Lake Taihu region could enhance the formation of cyanobacterial blooms and consequently lead to a further decrease in water clarity. This study suggested that coupling remote sensing monitoring and long-term in-situ observations could provide robust evidence and new insights to elucidate long-term dynamics in aquatic ecosystem evolution.

Swift Multi-wavelength Observing Campaigns: Strategies and Outcomes

NASA Technical Reports Server (NTRS)

Krimm, Hans A.

2007-01-01

The Swift gamma-ray burst explorer has been operating since December 2004 as both a gamma-ray burst (GRB) monitor and telescope and a multi-wavelength observatory, covering the energy range from V band and near UV to hard X rays above 150 keV. It is designed to rapidly repoint to observe newly discovered GRBs, and this maneuverability, combined with an easily changed observing program, allows Swift to also be an effective multiwavelength observatory for non-GRB targets, both as targets of opportunity and pre-planned multi-wavelength observing campaigns. Blazars are particularly attractive targets for coordinated campaigns with TeV experiments since many blazars are bright in both the hard X-ray and TeV energy ranges. Successful coordinated campaigns have included observations of 3C454.3 during its 2005 outburst. The latest Swift funding cycles allow for non- GRB related observations to be proposed. The Burst Alert Telescope on Swift also serves as a hard X-ray monitor with a public web page that includes light curves for over 400 X-ray sources and is used to alert the astronomical community about increased activity from both known and newly discovered sources. This presentation mill include Swift capabilities, strategies and policies for coordinated multi-wavelength observations as well as discussion of the potential outcomes of such campaigns.

The PACA Project Ecology: Observing Campaigns, Outreach and Citizen Science

NASA Astrophysics Data System (ADS)

Yanamandra-Fisher, P. A.

2016-12-01

The PACA Project has three main components: observational campaigns aligned with scientific research; outreach to engage all forms of audiences and citizen science projects that aim to produce specific scientific results, by engaging professional scientific and amateur communities and a variety of audiences. The primary observational projects are defined by specific scientific goals by professionals, resulting in global observing campaigns involving a variety of observers, and observing techniques. Some of PACA's observing campaigns have included global characterization of comets (e.g., C/ISON, SidingSpring, 67P/Churyumov-Gerasimenko, Lovejoy, etc.), planets (Jupiter, Saturn and Mars) and currently expanding to include polarimetric exploration of solar system objects with small apertures and collaboration with CITIZEN CATE, a citizen science observing campaign to observe the 2017 Continental America Total Eclipse. Our Outreach campaigns leverage the multiple social media/platforms for at least two important reasons: (i) the immediate dissemination of observations and interaction with the global network and (ii) free or inexpensive resources for most of the participants. The use of social media is becoming prevalent in citizen science projects due to these factors. The final stage of the PACA ecosystem is the integration of these components into a publication. We shall highlight some of the interesting challenges and solutions of the PACA Project so far and provide a view of future projects in all three categories with new partnerships and collaborations.

Long-term variations of the upper atmosphere parameters on Rome ionosonde observations and their interpretation

NASA Astrophysics Data System (ADS)

Perrone, Loredana; Mikhailov, Andrey; Cesaroni, Claudio; Alfonsi, Lucilla; Santis, Angelo De; Pezzopane, Michael; Scotto, Carlo

2017-09-01

A recently proposed self-consistent approach to the analysis of thermospheric and ionospheric long-term trends has been applied to Rome ionosonde summer noontime observations for the (1957-2015) period. This approach includes: (i) a method to extract ionospheric parameter long-term variations; (ii) a method to retrieve from observed foF1 neutral composition (O, O2, N2), exospheric temperature, Tex and the total solar EUV flux with λ < 1050 Å; and (iii) a combined analysis of the ionospheric and thermospheric parameter long-term variations using the theory of ionospheric F-layer formation. Atomic oxygen, [O] and [O]/[N2] ratio control foF1 and foF2 while neutral temperature, Tex controls hmF2 long-term variations. Noontime foF2 and foF1 long-term variations demonstrate a negative linear trend estimated over the (1962-2010) period which is mainly due to atomic oxygen decrease after ˜1990. A linear trend in (δhmF2)11y estimated over the (1962-2010) period is very small and insignificant reflecting the absence of any significant trend in neutral temperature. The retrieved neutral gas density, ρ atomic oxygen, [O] and exospheric temperature, Tex long-term variations are controlled by solar and geomagnetic activity, i.e. they have a natural origin. The residual trends estimated over the period of ˜5 solar cycles (1957-2015) are very small (<0.5% per decade) and statistically insignificant.

Long term multiwavelength studies of the corona/disc connection in AGN

NASA Astrophysics Data System (ADS)

Buisson, D.; Lohfink, A.; Alston, W.; Fabian, A.; Gallo, L.; Kara, E.; Zoghbi, A.; Wilkins, D.; Miller, J.; Cackett, E.

2017-10-01

One way of increasing our understanding of AGN is determining the nature of the connection between the optical/UV emitting accretion disc and the X-ray emitting corona. Studies of variability in these two bands are a key tool for gaining insight into the processes involved. We will present results from a sample of long-term AGN monitoring campaigns in the optical, UV and X-ray with Swift. In particular, we will explore UV/optical-X-ray correlations and associated time lags. We will compare these measurements and the UV/optical RMS spectra with theoretical reprocessing models and confront recent claims of the observed lags being longer than those which are expected for a standard thin disc. Additionally, a new Swift monitoring campaign of the z=2 quasar PG 1247+267 allows us to probe the shorter wavelengths at the peak of the accretion disc spectrum, providing information on the region of the disc closest to the black hole. However, not all AGN show such correlations, including IRAS 13224-3809, the subject of a recent 1.5 Ms XMM observation. Using this and other examples, we will explore the possible reasons for the lack of observed correlation.

GLAS Long-Term Archive: Preservation and Stewardship for a Vital Earth Observing Mission

NASA Astrophysics Data System (ADS)

Fowler, D. K.; Moses, J. F.; Zwally, J.; Schutz, B. E.; Hancock, D.; McAllister, M.; Webster, D.; Bond, C.

2012-12-01

Data Stewardship, preservation, and reproducibility are fast becoming principal parts of a data manager's work. In an era of distributed data and information systems, it is of vital importance that organizations make a commitment to both current and long-term goals of data management and the preservation of scientific data. Satellite missions and instruments go through a lifecycle that involves pre-launch calibration, on-orbit data acquisition and product generation, and final reprocessing. Data products and descriptions flow to the archives for distribution on a regular basis during the active part of the mission. However there is additional information from the product generation and science teams needed to ensure the observations will be useful for long term climate studies. Examples include ancillary input datasets, product generation software, and production history as developed by the team during the course of product generation. These data and information will need to be archived after product data processing is completed. NASA has developed a set of Earth science data and information content requirements for long term preservation that is being used for all the EOS missions as they come to completion. Since the ICESat/GLAS mission was one of the first to end, NASA and NSIDC, in collaboration with the science team, are collecting data, software, and documentation, preparing for long-term support of the ICESat mission. For a long-term archive, it is imperative to preserve sufficient information about how products were prepared in order to ensure future researchers that the scientific results are accurate, understandable, and useable. Our experience suggests data centers know what to preserve in most cases. That is, the processing algorithms along with the Level 0 or Level 1a input and ancillary products used to create the higher-level products will be archived and made available to users. In other cases, such as pre-launch, calibration/validation, and test

Long-term fault creep observations in central California

NASA Astrophysics Data System (ADS)

Schulz, Sandra S.; Mavko, Gerald M.; Burford, Robert O.; Stuart, William D.

1982-08-01

The U.S. Geological Survey (USGS) has been monitoring aseismic fault slip in central California for more than 10 years as part of an earthquake prediction experiment. Since 1968, the USGS creep network has grown from one creep meter at the Cienega Winery south of Hollister to a 44-station network that stretches from Hayward, east of San Francisco Bay, to Palmdale in southern California. In general, the long-term slip pattern is most variable on sections of the faults where several magnitude 4 and larger earthquakes occurred during the recording period (e.g., Calaveras fault near Hollister and San Andreas fault between San Juan Bautista and Bear Valley). These fault sections are the most difficult to characterize with a single long-term slip rate. In contrast, sections of the faults that are seismically relatively quiet (e.g., San Andreas fault between Bear Valley and Parkfield) produce the steadiest creep records and are easiest to fit with a single long-term slip rate. Appendix is available with entire article on microfiche. Order from the American Geophysical Union, 2000 Florida Avenue, N.W., Washington, D.C. 20009. Document J82-004; $1.00. Payment must accompany order.

Global long-term ozone trends derived from different observed and modelled data sets

NASA Astrophysics Data System (ADS)

Coldewey-Egbers, M.; Loyola, D.; Zimmer, W.; van Roozendael, M.; Lerot, C.; Dameris, M.; Garny, H.; Braesicke, P.; Koukouli, M.; Balis, D.

2012-04-01

The long-term behaviour of stratospheric ozone amounts during the past three decades is investigated on a global scale using different observed and modelled data sets. Three European satellite sensors GOME/ERS-2, SCIAMACHY/ENVISAT, and GOME-2/METOP are combined and a merged global monthly mean total ozone product has been prepared using an inter-satellite calibration approach. The data set covers the 16-years period from June 1995 to June 2011 and it exhibits an excellent long-term stability, which is required for such trend studies. A multiple linear least-squares regression algorithm using different explanatory variables is applied to the time series and statistically significant positive trends are detected in the northern mid latitudes and subtropics. Global trends are also estimated using a second satellite-based Merged Ozone Data set (MOD) provided by NASA. For few selected geographical regions ozone trends are additionally calculated using well-maintained measurements of individual Dobson/Brewer ground-based instruments. A reasonable agreement in the spatial patterns of the trends is found amongst the European satellite, the NASA satellite, and the ground-based observations. Furthermore, two long-term simulations obtained with the Chemistry-Climate Models E39C-A provided by German Aerospace Center and UMUKCA-UCAM provided by University of Cambridge are analysed.

Residual infestation and recolonization during urban Triatoma infestans Bug Control Campaign, Peru.

PubMed

Barbu, Corentin M; Buttenheim, Alison M; Pumahuanca, Maria-Luz Hancco; Calderón, Javier E Quintanilla; Salazar, Renzo; Carrión, Malwina; Rospigliossi, Andy Catacora; Chavez, Fernando S Malaga; Alvarez, Karina Oppe; Cornejo del Carpio, Juan; Náquira, César; Levy, Michael Z

2014-12-01

Chagas disease vector control campaigns are being conducted in Latin America, but little is known about medium-term or long-term effectiveness of these efforts, especially in urban areas. After analyzing entomologic data for 56,491 households during the treatment phase of a Triatoma infestans bug control campaign in Arequipa, Peru, during 2003-2011, we estimated that 97.1% of residual infestations are attributable to untreated households. Multivariate models for the surveillance phase of the campaign obtained during 2009-2012 confirm that nonparticipation in the initial treatment phase is a major risk factor (odds ratio [OR] 21.5, 95% CI 3.35-138). Infestation during surveillance also increased over time (OR 1.55, 95% CI 1.15-2.09 per year). In addition, we observed a negative interaction between nonparticipation and time (OR 0.73, 95% CI 0.53-0.99), suggesting that recolonization by vectors progressively dilutes risk associated with nonparticipation. Although the treatment phase was effective, recolonization in untreated households threatens the long-term success of vector control.

The PACA Project: Creating Synergy Between Observing Campaigns, Outreach and Citizen Science

NASA Astrophysics Data System (ADS)

Yanamandra-Fisher, Padma

2017-04-01

The PACA (Pro-Am Collaborative Astronomy) Project's primary goal is to develop and build synergy between professional and amateur astronomers from observations in the many aspects of support of missions and campaigns. To achieve this, the PACA has three main components: observational campaigns aligned with scientific research; outreach to engage all forms of audiences and citizen science projects that aim to produce specific scientific results, by engaging professional scientific and amateur communities and a variety of audiences. The primary observational projects are defined by specific scientific goals by professionals, resulting in global observing campaigns involving a variety of observers, and observing techniques. Some of PACA's observing campaigns have included global characterization of comets (e.g., C/ISON, SidingSpring, 67P/Churyumov-Gerasimenko, Lovejoy, etc.), planets (Jupiter, Saturn and Mars) and currently expanded to include (i) polarimetric exploration of solar system objects with small apertures and (ii) in collaboration with CITIZEN CATE, a citizen science observing campaign to observe the 2017 Continental America Total Eclipse, engage many levels of informal audiences using interactive social media to participate in the campaign. Our Outreach campaigns leverage the multiple social media/platforms for at least two important reasons: (i) the immediate dissemination of observations and interaction with the global network and (ii) free or inexpensive resources for most of the participants. The final stage of the PACA ecosystem is the integration of these components into publications. We shall highlight some of the interesting challenges and solutions of the PACA Project so far and provide a view of future projects and new partnerships in all three categories.

Long-term Observations of Intense Precipitation Small-scale Spatial Variability in a Semi-arid Catchment

NASA Astrophysics Data System (ADS)

Cropp, E. L.; Hazenberg, P.; Castro, C. L.; Demaria, E. M.

2017-12-01

In the southwestern US, the summertime North American Monsoon (NAM) provides about 60% of the region's annual precipitation. Recent research using high-resolution atmospheric model simulations and retrospective predictions has shown that since the 1950's, and more specifically in the last few decades, the mean daily precipitation in the southwestern U.S. during the NAM has followed a decreasing trend. Furthermore, days with more extreme precipitation have intensified. The current work focuses the impact of these long-term changes on the observed small-scale spatial variability of intense precipitation. Since limited long-term high-resolution observational data exist to support such climatological-induced spatial changes in precipitation frequency and intensity, the current work utilizes observations from the USDA-ARS Walnut Gulch Experimental Watershed (WGEW) in southeastern Arizona. Within this 150 km^2 catchment over 90 rain gauges have been installed since the 1950s, measuring at sub-hourly resolution. We have applied geospatial analyses and the kriging interpolation technique to identify long-term changes in the spatial and temporal correlation and anisotropy of intense precipitation. The observed results will be compared with the previously model simulated results, as well as related to large-scale variations in climate patterns, such as the El Niño Southern Oscillation (ENSO) and the Pacific Decadal Oscillation (PDO).

Spatial variation of ultrafine particles and black carbon in two cities: results from a short-term measurement campaign.

PubMed

Klompmaker, Jochem O; Montagne, Denise R; Meliefste, Kees; Hoek, Gerard; Brunekreef, Bert

2015-03-01

Recently, short-term monitoring campaigns have been carried out to investigate the spatial variation of air pollutants within cities. Typically, such campaigns are based on short-term measurements at relatively large numbers of locations. It is largely unknown how well these studies capture the spatial variation of long term average concentrations. The aim of this study was to evaluate the within-site temporal and between-site spatial variation of the concentration of ultrafine particles (UFPs) and black carbon (BC) in a short-term monitoring campaign. In Amsterdam and Rotterdam (the Netherlands) measurements of number counts of particles larger than 10nm as a surrogate for UFP and BC were performed at 80 sites per city. Each site was measured in three different seasons of 2013 (winter, spring, summer). Sites were selected from busy urban streets, urban background, regional background and near highways, waterways and green areas, to obtain sufficient spatial contrast. Continuous measurements were performed for 30 min per site between 9 and 16 h to avoid traffic spikes of the rush hour. Concentrations were simultaneously measured at a reference site to correct for temporal variation. We calculated within- and between-site variance components reflecting temporal and spatial variations. Variance ratios were compared with previous campaigns with longer sampling durations per sample (24h to 14 days). The within-site variance was 2.17 and 2.44 times higher than the between-site variance for UFP and BC, respectively. In two previous studies based upon longer sampling duration much smaller variance ratios were found (0.31 and 0.09 for UFP and BC). Correction for temporal variation from a reference site was less effective for the short-term monitoring campaign compared to the campaigns with longer duration. Concentrations of BC and UFP were on average 1.6 and 1.5 times higher at urban street compared to urban background sites. No significant differences between the other

Long-term irradiance observation and short-term flare prediction with LYRA on PROBA2

NASA Astrophysics Data System (ADS)

Dammasch, Ingolf; Dominique, Marie; West, Matthew; Katsiyannis, Thanassis; Ryan, Daniel; Wauters, Laurence

The solar radiometer LYRA on board the ESA micro-satellite PROBA2 has observed the Sun continuously since January 2010 in various spectral band passes, and has gained a considerable data base. Two of the LYRA channels cover the irradiance between soft X-ray and extreme ultraviolet. The variation of the sunspot number appears to show a strong similarity with the variation of these channels, when their long-range development is taken into account. The same holds for SXR levels observed by the GOES satellites. Due to LYRA's bandwidth and coverage of various active-region temperatures, its relatively smooth development may yield some information on the structure of the current solar cycle. On its websites, LYRA presents not only EUV and SXR time series in near real-time, but also information on flare parameters and long-term irradiance and sunspot levels. It will be demonstrated whether it is possible to aid space weather forecast with these statistical data, especially for the prediction of expected flare strength on a daily basis.

Residual Infestation and Recolonization during Urban Triatoma infestans Bug Control Campaign, Peru1

PubMed Central

Buttenheim, Alison M.; Pumahuanca, Maria-Luz Hancco; Calderón, Javier E. Quintanilla; Salazar, Renzo; Carrión, Malwina; Rospigliossi, Andy Catacora; Chavez, Fernando S. Malaga; Alvarez, Karina Oppe; Cornejo del Carpio, Juan; Náquira, César; Levy, Michael Z.

2014-01-01

Chagas disease vector control campaigns are being conducted in Latin America, but little is known about medium-term or long-term effectiveness of these efforts, especially in urban areas. After analyzing entomologic data for 56,491 households during the treatment phase of a Triatoma infestans bug control campaign in Arequipa, Peru, during 2003–2011, we estimated that 97.1% of residual infestations are attributable to untreated households. Multivariate models for the surveillance phase of the campaign obtained during 2009–2012 confirm that nonparticipation in the initial treatment phase is a major risk factor (odds ratio [OR] 21.5, 95% CI 3.35–138). Infestation during surveillance also increased over time (OR 1.55, 95% CI 1.15–2.09 per year). In addition, we observed a negative interaction between nonparticipation and time (OR 0.73, 95% CI 0.53–0.99), suggesting that recolonization by vectors progressively dilutes risk associated with nonparticipation. Although the treatment phase was effective, recolonization in untreated households threatens the long-term success of vector control. PMID:25423045

Long-term Ultraviolet Monitoring of a Tidal Disruption Event at only 90 Mpc

NASA Astrophysics Data System (ADS)

Maksym, W. Peter; Cenko, Bradley; Eracleous, Michael; Keel, William C.; Irwin, Jimmy; Sigurdsson, Steinn; Fruchter, Andrew; Gezari, Suvi; Bogdanovic, Tamara; Roth, Katherine

2018-01-01

At only 90 Mpc, ASASSN-14li is one of the nearest tidal disruption events (TDEs) to permit high-quality multi-wavelength monitoring, and is the first TDE with ultraviolet spectroscopic observations between Lyman alpha and Mg II λ2800Å. We present results from a continued long-term ultraviolet monitoring campaign with the Hubble Space Telescope. Prior observations had showed an array of broad emission lines common to Seyferts. Surpisingly, however, uncommon lines such as He II λ1640Å, N III] λ1750Å and N IV] λ1486Å had been enhanced, whereas others such as C III] λ1909Å and Mg II λ2800Å are notably absent. Our campaign shows contnued continuum emission accompanied by the gradual disappearance of broad line emission, which may indicate the gradual disappearance of a TDE wind as the accretion rate declines to sub-critical levels. Variability of the semi-forbidden lines supports stimulation by the TDE. A continued absence of low-ionization lines like Mg II in our monitoring may constrain the presence of ionized unbound material at large radii.

Recent Results with Transatlantic GeTT Campaign

DTIC Science & Technology

1999-12-01

which are driven by H-masers. Frequent comparisons between GPS CP and TWSTFT throughout the campaign allow a comparison of the long-term stability of...the two entirely independent techniques. Small discrepancies between the time transfer by GPS CP and the time transfer by TWSTFT have been observed...density for the GeTT values in comparison to the other time-transfer methods: two-way satellite time and frequency transfer ( TWSTFT ) and Circular T

Long-Term Oceanographic Observations in Western Massachusetts Bay Offshore of Boston, Massachusetts: Data Report for 1989-2002

USGS Publications Warehouse

Butman, Bradford; Bothner, Michael H.; Alexander, P. Soupy; Lightsom, Frances L.; Martini, Marinna A.; Gutierrez, Benjamin T.; Strahle, William S.

2004-01-01

This data report presents long-term oceanographic observations made in western Massachusetts Bay at two locations: (1) 42 deg 22.6' N., 70 deg 47.0' W. (Site A, 33 m water depth) from December 1989 through December 2002 (figure 1), and (2) 42 deg 9.8' N., 70 deg 38.4' W. (Site B, 21 m water depth) from October 1997 through December 2002. Site A is approximately 1 km south of the new ocean outfall that began discharging treated sewage effluent from the Boston metropolitan area into Massachusetts Bay on September 6, 2000. These long-term oceanographic observations have been collected by the U.S. Geological Survey (USGS) in partnership with the Massachusetts Water Resources Authority (MWRA) and with logistical support from the U.S. Coast Guard (USCG - http://www.uscg.mil). This report presents time series data through December 2002, updating a similar report that presented data through December 2000 (Butman and others, 2002). In addition, the Statistics and Mean Flow sections include some new plots and tables and the format of the report has been streamlined by combining yearly figures into single .pdfs. Figure 1 (PDF format) The long-term measurements are planned to continue at least through 2005. The long-term oceanographic observations at Sites A and B are part of a USGS study designed to understand the transport and long-term fate of sediments and associated contaminants in the Massachusetts bays. (See http://woodshole.er.usgs.gov/project-pages/bostonharbor/ and Butman and Bothner, 1997.) The long-term observations document seasonal and inter-annual changes in currents, hydrography, and suspended-matter concentration in western Massachusetts Bay, and the importance of infrequent catastrophic events, such as major storms or hurricanes, in sediment resuspension and transport. They also provide observations for testing numerical models of circulation. This data report presents a description of the field program and instrumentation, an overview of the data through

Long term observation of low altitude atmosphere by high precision polarization lidar

NASA Astrophysics Data System (ADS)

Shiina, Tatsuo; Noguchi, Kazuo; Fukuchi, Tetsuo

2011-11-01

Prediction of weather disaster such as heavy rain and light strike is an earnest desire. Successive monitoring of the low altitude atmosphere is important to predict it. The weather disaster often befalls with a steep change in a local area. It is hard for usual meteorological equipments to capture and alert it speedily. We have been developed the near range lidar to capture and analyze the low altitude atmosphere. In this study, high precision polarization lidar was developed to observe the low altitude atmosphere. This lidar has the high extinction ratio of polarization of >30dB to detect the small polarization change of the atmosphere. The change of the polarization in the atmosphere leads to the detection of the depolarization effect and the Faraday effect, which are caused by ice-crystals and lightning discharge, respectively. As the lidar optics is "inline" type, which means common use of optics for transmitter and receiver, it can observe the near range echo with the narrow field of view. The long-term observation was accomplished at low elevation angle. It aims to monitor the low altitude atmosphere under the cloud base and capture its spatial distribution and convection process. In the viewpoint of polarization, the ice-crystals' flow and concentration change of the aerosols are monitored. The observation has been continued in the cloudy and rainy days. The thunder cloud is also a target. In this report, the system specification is explained to clear the potential and the aims. The several observation data including the long-term observation will be shown with the consideration of polarization analysis.

Georgia Hospital Association leads long-term staff recruiting effort. Reaches wide target audience through innovative media use.

PubMed

Botvin, Judith D

2003-01-01

The Georgia Hospital Association (GHA), faced with a critical healthcare workforce shortage, created a long-term response to the problem by creating a Workforce Shortage Media Campaign. Its single purpose was to encourage Georgians to pursue careers in healthcare. The four-week campaign took six months to develop and included print, radio and television.

Estimating long-term multivariate progression from short-term data.

PubMed

Donohue, Michael C; Jacqmin-Gadda, Hélène; Le Goff, Mélanie; Thomas, Ronald G; Raman, Rema; Gamst, Anthony C; Beckett, Laurel A; Jack, Clifford R; Weiner, Michael W; Dartigues, Jean-François; Aisen, Paul S

2014-10-01

Diseases that progress slowly are often studied by observing cohorts at different stages of disease for short periods of time. The Alzheimer's Disease Neuroimaging Initiative (ADNI) follows elders with various degrees of cognitive impairment, from normal to impaired. The study includes a rich panel of novel cognitive tests, biomarkers, and brain images collected every 6 months for as long as 6 years. The relative timing of the observations with respect to disease pathology is unknown. We propose a general semiparametric model and iterative estimation procedure to estimate simultaneously the pathological timing and long-term growth curves. The resulting estimates of long-term progression are fine-tuned using cognitive trajectories derived from the long-term "Personnes Agées Quid" study. We demonstrate with simulations that the method can recover long-term disease trends from short-term observations. The method also estimates temporal ordering of individuals with respect to disease pathology, providing subject-specific prognostic estimates of the time until onset of symptoms. When the method is applied to ADNI data, the estimated growth curves are in general agreement with prevailing theories of the Alzheimer's disease cascade. Other data sets with common outcome measures can be combined using the proposed algorithm. Software to fit the model and reproduce results with the statistical software R is available as the grace package. ADNI data can be downloaded from the Laboratory of NeuroImaging. Copyright © 2014 The Alzheimer's Association. Published by Elsevier Inc. All rights reserved.

Evaluation of Surface Flux Parameterizations with Long-Term ARM Observations

DOE PAGES

Liu, Gang; Liu, Yangang; Endo, Satoshi

2013-02-01

Surface momentum, sensible heat, and latent heat fluxes are critical for atmospheric processes such as clouds and precipitation, and are parameterized in a variety of models ranging from cloud-resolving models to large-scale weather and climate models. However, direct evaluation of the parameterization schemes for these surface fluxes is rare due to limited observations. This study takes advantage of the long-term observations of surface fluxes collected at the Southern Great Plains site by the Department of Energy Atmospheric Radiation Measurement program to evaluate the six surface flux parameterization schemes commonly used in the Weather Research and Forecasting (WRF) model and threemore » U.S. general circulation models (GCMs). The unprecedented 7-yr-long measurements by the eddy correlation (EC) and energy balance Bowen ratio (EBBR) methods permit statistical evaluation of all six parameterizations under a variety of stability conditions, diurnal cycles, and seasonal variations. The statistical analyses show that the momentum flux parameterization agrees best with the EC observations, followed by latent heat flux, sensible heat flux, and evaporation ratio/Bowen ratio. The overall performance of the parameterizations depends on atmospheric stability, being best under neutral stratification and deteriorating toward both more stable and more unstable conditions. Further diagnostic analysis reveals that in addition to the parameterization schemes themselves, the discrepancies between observed and parameterized sensible and latent heat fluxes may stem from inadequate use of input variables such as surface temperature, moisture availability, and roughness length. The results demonstrate the need for improving the land surface models and measurements of surface properties, which would permit the evaluation of full land surface models.« less

Two long-term slow slip events around Tokyo Bay found by GNSS observation during 1996-2011

NASA Astrophysics Data System (ADS)

Tanaka, Yoshiyuki; Yabe, Suguru

2017-03-01

Slow slip events (SSEs) with durations ranging from days to more than a decade have been observed in plate subduction zones around the world. In the Kanto district in Japan, several SSEs have been identified based on geodetic observations. However, none of these events have had durations largely exceeding a year. In this study, we show that long-term SSEs with durations longer than 3 years occurred before the year 2000 and after 2007 on the upper interface of the Philippine Sea Plate at depths of 30-40 km. The fault model determined by inversion of global navigation satellite system data is located northeast of Tokyo Bay, where a seismic gap and low seismic wave velocities were detected by seismological observations. Moreover, the acceleration periods of the fault slip corresponded well with increases in the background seismicity for shallower earthquakes. The slip history was also temporally correlated with the long-term shear stress changes governed mainly by non-tidal variations in the ocean bottom pressure. However, the predicted slip from the long-term stress change was too small to reproduce the observed slow slips. To prove the causal relationship between the SSEs and the external stress change, more advanced modeling is necessary to confirm whether such a small slip can trigger an SSE.[Figure not available: see fulltext.

The Results of the 2013 Pro-Am Wolf-Rayet Campaign

NASA Astrophysics Data System (ADS)

Aldoretta, E. J.; St-Louis, N.; Richardson, N. D.; Moffat, A. F. J.; Eversberg, T.; Hill, G. M.; World-Wide WR Pro-Am Campaign Team

Professional and amateur astronomers around the world contributed to a 4-month long campaign in 2013, mainly in spectroscopy but also in photometry, interferometry and polarimetry, to observe the first 3 Wolf-Rayet stars discovered: WR 134 (WN6b), WR 135 (WC8) and WR 137 (WC7pd+O9). Each of these stars are interesting in their own way, showing a variety of stellar wind structures. The spectroscopic data from this campaign were reduced and analyzed for WR 134 in order to better understand its behavior and long-term periodicity in the context of CIRs in the wind. We will be presenting the results of these spectroscopic data, which include the confirmation of the CIR variability and a time-coherency of ˜ 40 days (half-life of ˜ 20 days).

Constraints on Southern Ocean CO2 Fluxes and Seasonality from Atmospheric Vertical Gradients Observed on Multiple Airborne Campaigns

NASA Astrophysics Data System (ADS)

McKain, K.; Sweeney, C.; Stephens, B. B.; Long, M. C.; Jacobson, A. R.; Basu, S.; Chatterjee, A.; Weir, B.; Wofsy, S. C.; Atlas, E. L.; Blake, D. R.; Montzka, S. A.; Stern, R.

2017-12-01

The Southern Ocean plays an important role in the global carbon cycle and climate system, but net CO2 flux into the Southern Ocean is difficult to measure and model because it results from large opposing and seasonally-varying fluxes due to thermal forcing, biological uptake, and deep-water mixing. We present an analysis to constrain the seasonal cycle of net CO2 exchange with the Southern Ocean, and the magnitude of summer uptake, using the vertical gradients in atmospheric CO2 observed during three aircraft campaigns in the southern polar region. The O2/N2 Ratio and CO2 Airborne Southern Ocean Study (ORCAS) was an airborne campaign that intensively sampled the atmosphere at 0-13 km altitude and 45-75 degrees south latitude in the austral summer (January-February) of 2016. The global airborne campaigns, the HIAPER Pole-to-Pole Observations (HIPPO) study and the Atmospheric Tomography Mission (ATom), provide additional measurements over the Southern Ocean from other seasons and multiple years (2009-2011, 2016-2017). Derivation of fluxes from measured vertical gradients requires robust estimates of the residence time of air in the polar tropospheric domain, and of the contribution of long-range transport from northern latitudes outside the domain to the CO2 gradient. We use diverse independent approaches to estimate both terms, including simulations using multiple transport and flux models, and observed gradients of shorter-lived tracers with specific sources regions and well-known loss processes. This study demonstrates the utility of aircraft profile measurements for constraining large-scale air-sea fluxes for the Southern Ocean, in contrast to those derived from the extrapolation of sparse ocean and atmospheric measurements and uncertain flux parameterizations.

Reviewing long-term antidepressants can reduce drug burden: a prospective observational cohort study

PubMed Central

Johnson, Chris F; Macdonald, Hector J; Atkinson, Pauline; Buchanan, Alasdair I; Downes, Noreen; Dougall, Nadine

2012-01-01

Background Antidepressant prescribing continues to rise. Contributing factors are increased long-term prescribing and possibly the use of higher selective serotonin re-uptake inhibitor (SSRI) doses. Aim To review general practice patients prescribed the same antidepressant long-term (≥2 years) and evaluate prescribing and management pre and post-review. Design and setting Prospective observational cohort study using routine data from 78 urban general practices, Scotland. Method All patients prescribed antidepressants (excluding amitriptyline) for ≥2 years were identified from records November 2009 to March 2010. GPs selected patients for face-to-face review of clinical condition and medication, December 2009 to September 2010. Pre- and post-review data were collected; average antidepressant doses and changes in prescribed daily doses were calculated. Onward referral to support services was recorded. Results 8.6% (33 312/388 656) of all registered patients were prescribed an antidepressant, 47.1% (15 689) were defined as long-term users and 2849 (18.2%) were reviewed. 811 (28.5%) patients reviewed had a change in antidepressant therapy: 7.0% stopped, 12.8% reduced dose, 5.3% increased dose, and 3.4% changed antidepressant, resulting in 9.5% (95% CI = 9.1% to 9.8% P<0.001) reduction in prescribed daily dose and 8.1% reduction in prescribing costs. 6.3% were referred onwards, half to NHS Mental Health Services. Pre-review SSRI doses were 10–30% higher than previously reported. Conclusion Almost half of all people prescribed antidepressants were long-term users. Appropriate reductions in prescribing can be achieved by reviewing patients. Higher SSRI doses may be contributing to current antidepressant growth. PMID:23211181

Retrievals of Sea Surface Emissivity and Skin Temperature from M-AERI Observations from the ACAPEX/CalWater2 Campaign

NASA Astrophysics Data System (ADS)

Gero, P. J.; Westphall, M.; Knuteson, R.; Knuteson, R. O.; Smith, W.

2016-12-01

The Atmospheric Emitted Radiance Interferometer (AERI) is a ground-based instrument developed at the University of Wisconsin-Madison that measures downwelling thermal infrared radiance from the atmosphere. Observations are made in the 520-3020 cm-1 (3.3-19 μm) spectral range with a resolution of 1 cm-1, with an accuracy better than 1% of ambient radiance. These observations can be used to obtain vertical profiles of tropospheric temperature and water vapor in the lowest 3 km of the troposphere, as well as measurements of the concentration of various trace gases and microphysical and optical properties of clouds and aerosols. The U.S Department of Energy's (DOE) Atmospheric Radiation Measurement (ARM) program currently operates about ten AERIs at various fixed and mobile sites worldwide, addressing a diverse range of scientific goals from process studies to long-term climate observations. One of the instruments is a marine version (M-AERI) that has the capability to view scenes ±45° from the horizon, and can be used to observe sea surface properties such as skin temperature and emissivity. The M-AERI was deployed on the NOAA Ship Ronald Brown in 2015 as part of the ACAPEX/CalWater2 campaign to study atmospheric rivers in the Pacific Ocean. We present results from the M-AERI from this campaign of retrievals of skin temperature and sea surface emissivity as a function of view angle and wind speed, as well as comparisons to various models.

ISINGLASS Auroral Sounding Rocket Campaign Data Synthesis: Radar, Imagery, and In Situ Observations

NASA Astrophysics Data System (ADS)

Clayton, R.; Lynch, K. A.; Evans, T.; Hampton, D. L.; Burleigh, M.; Zettergren, M. D.; Varney, R. H.; Reimer, A.; Hysell, D. L.; Michell, R.; Samara, M.; Grubbs, G. A., II

2017-12-01

E-field and flow variations across auroral arc boundaries are typically sub-grid measurements for ground based sensors such as radars and imagers, even for quiet stable arcs. In situ measurements can provide small scale resolution, but only provide a snapshot at a localized time and place. Using ground based and in situ measurements of the ISINGLASS auroral sounding rocket campaign in conjunction, we use the in situ measurements to validate ground based synthesis of these small scale observations based on the classification of auroral arcs in Marklund(1984). With validation of this technique, sub-grid information can be gained from radar data using particular visible auroral features during times where only ground based measurements are present. The ISINGLASS campaign (Poker Flat Alaska, Winter 2017) included the nights of Feb 22 2017 and Mar 02 2017, which possessed multiple stable arc boundaries that can be used for synthesis, including the two events into which the ISINGLASS rockets were launched. On Mar 02 from 0700 to 0800 UT, two stable slowly southward-propagating auroral arcs persisted within the instrument field of view, and lasted for a period of >15min. The second of these events contains the 36.304 rocket trajectory, while both events have full ground support from camera imagery and radar. Data synthesis from these events is accomplished using Butler (2010), Vennell (2009), and manually selected auroral boundaries from ground based cameras. With determination of the auroral arc boundaries from ground based imagery, a prediction of the fields along the length of a long straight arc boundary can be made using the ground based radar data, even on a sub-radar-grid scale, using the Marklund arc boundary classification. We assume that fields everywhere along a long stable arc boundary should be the same. Given a long stable arc, measurements anywhere along the arc (i.e. from PFISR) can be replicated along the length of the boundary. This prediction can then

The OJ287 observing campaign hots up

NASA Astrophysics Data System (ADS)

Poyner, G.

2006-12-01

In the August 2006 issue of the Journal [116(4), 163-164] I gave details of the BAAVSS observing campaign to monitor the binary black hole OJ287. The campaign is now once again in full swing for the 2006/2007 season, now that solar conjunction is finally over. During the summer break, new analysis was done on the BAAVSS & TA data by Dr Mauri Valtonen (Dept of Physics and Tuorla Observatory, University of Turku, Finland & Dept of Physics, University of the West Indies, Trinidad) and Dr Mark Kidger (Herschel Science Centre, European Space Astronomy centre, Villafranca del Castillo Satellite Tracking Station, Madrid, Spain, & INSA) and Dr Harry Lehto (NORDITA, Copenhagen, Denmark). A detailed examination of these data from the past 15 years, and especially the last 12 months, has led to some interesting conclusions.

[Long-term psychiatric hospitalizations].

PubMed

Plancke, L; Amariei, A

2017-02-01

Long-term hospitalizations in psychiatry raise the question of desocialisation of the patients and the inherent costs. Individual indicators were extracted from a medical administrative database containing full-time psychiatric hospitalizations for the period 2011-2013 of people over 16 years old living in the French region of Nord-Pas-de-Calais. We calculated the proportion of people who had experienced a hospitalization with a duration of 292 days or more during the study period. A bivariate analysis was conducted, then ecological data (level of health-care offer, the deprivation index and the size of the municipalities of residence) were included into a multilevel regression model in order to identify the factors significantly related to variability of long-term hospitalization rates. Among hospitalized individuals in psychiatry, 2.6% had had at least one hospitalization of 292 days or more during the observation period; the number of days in long-term hospitalization represented 22.5% of the total of days of full-time hospitalization in psychiatry. The bivariate analysis revealed that seniority in the psychiatric system was strongly correlated with long hospitalization rates. In the multivariate analysis, the individual indicators the most related to an increased risk of long-term hospitalization were: total lack of autonomy (OR=9.0; 95% CI: 6.7-12.2; P<001); diagnoses of psychological development disorders (OR=9.7; CI95%: 4.5-20.6; P<.001); mental retardation (OR=4.5; CI95%: 2.5-8.2; P<.001): schizophrenia (OR=3.0; CI95%: 1.7-5.2; P<.001); compulsory hospitalization (OR=1.7; CI95%: 1.4-2.1; P<.001); having experienced therapeutic isolation (OR=1.8; CI95%: 1.5-2.1; P<.001). Variations of long-term hospitalization rates depending on the type of establishment were very high, but the density of hospital beds or intensity of ambulatory activity services were not significantly linked to long-term hospitalization. The inhabitants of small urban units had

Evaluation of antismoking advertising campaigns.

PubMed

Goldman, L K; Glantz, S A

1998-03-11

Active and passive smoking are the first and third leading preventable causes of death. Many states are running or initiating antitobacco media campaigns. To review research on the effectiveness of different antismoking messages and published evidence of the effectiveness of paid antismoking advertising. Focus group studies conducted by professional advertising agencies that contract with California, Massachusetts, and Michigan to run their antismoking advertising campaigns, the Centers for Disease Control and Prevention's Media Campaign Resource Book, and copies of the advertisements. In total, we reviewed the results of 186 focus groups involving more than 1500 children and adults dealing with 118 advertisements that had actually been aired and additional concept advertisements that were not produced. Published literature was located using MEDLINE and standard bibliographic sources on the effectiveness of large, paid antitobacco media campaigns. We also reviewed reports and studies conducted by, or for, the California and Massachusetts health departments on program effectiveness, and conducted our own comparison of California vs Massachusetts using cigarette consumption data from the Tobacco Institute. All available studies. Eight advertising strategies to prevent people from starting to smoke and persuading them to stop were reviewed: industry manipulation, secondhand smoke, addiction, cessation, youth access, short-term effects, long-term health effects, and romantic rejection. These focus groups identified strategies that would be expected to be effective and ineffective. Regression analysis was used to compare the cost-effectiveness of the California and Massachusetts programs. Focus group participants indicated that industry manipulation and secondhand smoke are the most effective strategies for denormalizing smoking and reducing cigarette consumption. Addiction and cessation can be effective when used in conjunction with the industry manipulation and

Clean Hands for Life: results of a large, multicentre, multifaceted, social marketing hand-hygiene campaign.

PubMed

Forrester, L A; Bryce, E A; Mediaa, A K

2010-03-01

A year-long multifaceted hand-hygiene campaign entitled Clean Hands for Life targeting individual, environmental and organisational factors that influence healthcare worker (HCW) hand-hygiene behaviour was implemented in 36 acute and long-term care facilities in Vancouver Coastal Health region. The campaign involved rotation of ten novel posters, two poster contests, and distribution of multiple promotional items. A social marketing approach was used to implement and monitor the effectiveness of the campaign. Evaluation included quality assurance surveys, staff surveys (baseline, mid- and post-campaign), and focus groups. A total of 141 poster contest submissions was received, 5452 staff surveys completed and 14 focus groups conducted. Overall knowledge of the importance of hand-hygiene and intention to clean hands was high at baseline. No significant differences were observed when mid- and post-campaign scores were compared to baseline. The majority (89.5%) of HCWs reported that they preferred soap and water over alcohol hand gel. A significant increase in the self-reported use of hand-hygiene products was observed particularly among HCWs not providing direct patient care. Barriers to hand-hygiene included inappropriate placement of sinks, traffic flow issues, inadequately stocked washrooms, workload and time constraints. Organisational support was visible throughout the campaign. The results showed that social marketing is an effective approach in engaging HCWs. Hand-hygiene campaigns that focus almost exclusively on increasing awareness among HCWs may not be as successful as multifaceted campaigns or campaigns that target identified barriers to hand-hygiene. Copyright 2009 The Hospital Infection Society. Published by Elsevier Ltd. All rights reserved.

Evolvable Mars Campaign Long Duration Habitation Strategies: Architectural Approaches to Enable Human Exploration Missions

NASA Technical Reports Server (NTRS)

Simon, Matthew A.; Toups, Larry; Howe, A. Scott; Wald, Samuel I.

2015-01-01

The Evolvable Mars Campaign (EMC) is the current NASA Mars mission planning effort which seeks to establish sustainable, realistic strategies to enable crewed Mars missions in the mid-2030s timeframe. The primary outcome of the Evolvable Mars Campaign is not to produce "The Plan" for sending humans to Mars, but instead its intent is to inform the Human Exploration and Operations Mission Directorate near-term key decisions and investment priorities to prepare for those types of missions. The FY'15 EMC effort focused upon analysis of integrated mission architectures to identify technically appealing transportation strategies, logistics build-up strategies, and vehicle designs for reaching and exploring Mars moons and Mars surface. As part of the development of this campaign, long duration habitats are required which are capable of supporting crew with limited resupply and crew abort during the Mars transit, Mars moons, and Mars surface segments of EMC missions. In particular, the EMC design team sought to design a single, affordable habitation system whose manufactured units could be outfitted uniquely for each of these missions and reused for multiple crewed missions. This habitat system must provide all of the functionality to safely support 4 crew for long durations while meeting mass and volume constraints for each of the mission segments set by the chosen transportation architecture and propulsion technologies. This paper describes several proposed long-duration habitation strategies to enable the Evolvable Mars Campaign through improvements in mass, cost, and reusability, and presents results of analysis to compare the options and identify promising solutions. The concepts investigated include several monolithic concepts: monolithic clean sheet designs, and concepts which leverage the co-manifested payload capability of NASA's Space Launch System (SLS) to deliver habitable elements within the Universal Payload Adaptor between the SLS upper stage and the Orion

The Wisconsin/GSFC Hale-Bopp Observing Campaign

NASA Astrophysics Data System (ADS)

Scherb, F.; Roesler, F. L.; Harris, W. M.; Nordsieck, K. H.; Anderson, C.; Klinglesmith, D. A., III; Woodward, R. C.; Mierkiewicz, E. J.; Haffner, L. M.; Tufte, S. L.; Oliversen, R. J.; Hilton, G. M.; Doane, N.; Tilleman, T.; Vincent, M.

1997-07-01

From September 1996 to April 1997, we conducted an extensive campaign of observations of several atomic (O, C, H), ionic (H_2O(+) ), and molecular (OH, C_2, C_3, CN, NH_2) emissions from Comet Hale-Bopp, using a variety of telescopes (McMath-Pierce, WHAM, Burrel-Schmidt, WIYN, PBO, WISP), instruments (imagers, Fabry-Perot and grating spectrometers, polarimeters), and data formats (spectra, images, datacubes). We will present an overview of the observations, and highlight early results, some of which will be presented in detail in poster papers at this meeting.

The OLI Radiometric Scale Realization Round Robin Measurement Campaign

NASA Technical Reports Server (NTRS)

Cutlip, Hansford; Cole,Jerold; Johnson, B. Carol; Maxwell, Stephen; Markham, Brian; Ong, Lawrence; Hom, Milton; Biggar, Stuart

2011-01-01

A round robin radiometric scale realization was performed at the Ball Aerospace Radiometric Calibration Laboratory in January/February 2011 in support of the Operational Land Imager (OLI) Program. Participants included Ball Aerospace, NIST, NASA Goddard Space Flight Center, and the University of Arizona. The eight day campaign included multiple observations of three integrating sphere sources by nine radiometers. The objective of the campaign was to validate the radiance calibration uncertainty ascribed to the integrating sphere used to calibrate the OLI instrument. The instrument level calibration source uncertainty was validated by quatnifying: (1) the long term stability of the NIST calibrated radiance artifact, (2) the responsivity scale of the Ball Aerospace transfer radiometer and (3) the operational characteristics of the large integrating sphere.

Long-term metapopulation study of the Glanville fritillary butterfly (Melitaea cinxia): survey methods, data management, and long-term population trends.

PubMed

Ojanen, Sami P; Nieminen, Marko; Meyke, Evgeniy; Pöyry, Juha; Hanski, Ilkka

2013-10-01

Long-term observational studies conducted at large (regional) spatial scales contribute to better understanding of landscape effects on population and evolutionary dynamics, including the conditions that affect long-term viability of species, but large-scale studies are expensive and logistically challenging to keep running for a long time. Here, we describe the long-term metapopulation study of the Glanville fritillary butterfly (Melitaea cinxia) that has been conducted since 1991 in a large network of 4000 habitat patches (dry meadows) within a study area of 50 by 70 km in the Åland Islands in Finland. We explain how the landscape structure has been described, including definition, delimitation, and mapping of the habitat patches; methods of field survey, including the logistics, cost, and reliability of the survey; and data management using the EarthCape biodiversity platform. We describe the long-term metapopulation dynamics of the Glanville fritillary based on the survey. There has been no long-term change in the overall size of the metapopulation, but the level of spatial synchrony and hence the amplitude of fluctuations in year-to-year metapopulation dynamics have increased over the years, possibly due to increasing frequency of exceptional weather conditions. We discuss the added value of large-scale and long-term population studies, but also emphasize the need to integrate more targeted experimental studies in the context of long-term observational studies. For instance, in the case of the Glanville fritillary project, the long-term study has produced an opportunity to sample individuals for experiments from local populations with a known demographic history. These studies have demonstrated striking differences in dispersal rate and other life-history traits of individuals from newly established local populations (the offspring of colonizers) versus individuals from old, established local populations. The long-term observational study has stimulated the

Long-term metapopulation study of the Glanville fritillary butterfly (Melitaea cinxia): survey methods, data management, and long-term population trends

PubMed Central

Ojanen, Sami P; Nieminen, Marko; Meyke, Evgeniy; Pöyry, Juha; Hanski, Ilkka

2013-01-01

Long-term observational studies conducted at large (regional) spatial scales contribute to better understanding of landscape effects on population and evolutionary dynamics, including the conditions that affect long-term viability of species, but large-scale studies are expensive and logistically challenging to keep running for a long time. Here, we describe the long-term metapopulation study of the Glanville fritillary butterfly (Melitaea cinxia) that has been conducted since 1991 in a large network of 4000 habitat patches (dry meadows) within a study area of 50 by 70 km in the Åland Islands in Finland. We explain how the landscape structure has been described, including definition, delimitation, and mapping of the habitat patches; methods of field survey, including the logistics, cost, and reliability of the survey; and data management using the EarthCape biodiversity platform. We describe the long-term metapopulation dynamics of the Glanville fritillary based on the survey. There has been no long-term change in the overall size of the metapopulation, but the level of spatial synchrony and hence the amplitude of fluctuations in year-to-year metapopulation dynamics have increased over the years, possibly due to increasing frequency of exceptional weather conditions. We discuss the added value of large-scale and long-term population studies, but also emphasize the need to integrate more targeted experimental studies in the context of long-term observational studies. For instance, in the case of the Glanville fritillary project, the long-term study has produced an opportunity to sample individuals for experiments from local populations with a known demographic history. These studies have demonstrated striking differences in dispersal rate and other life-history traits of individuals from newly established local populations (the offspring of colonizers) versus individuals from old, established local populations. The long-term observational study has stimulated the

Assessing Forest Carbon Response to Climate Change and Disturbances Using Long-term Hydro-climatic Observations and Simulations

NASA Astrophysics Data System (ADS)

Trettin, C.; Dai, Z.; Amatya, D. M.

2014-12-01

Long-term climatic and hydrologic observations on the Santee Experimental Forest in the lower coastal plain of South Carolina were used to estimate long-term changes in hydrology and forest carbon dynamics for a pair of first-order watersheds. Over 70 years of climate data indicated that warming in this forest area in the last decades was faster than the global mean; 35+ years of hydrologic records showed that forest ecosystem succession three years following Hurricane Hugo caused a substantial change in the ratio of runoff to precipitation. The change in this relationship between the paired watersheds was attributed to altered evapotranspiration processes caused by greater abundance of pine in the treatment watershed and regeneration of the mixed hardwood-pine forest on the reference watershed. The long-term records and anomalous observations are highly valuable for reliable calibration and validation of hydrological and biogeochemical models capturing the effects of climate variability. We applied the hydrological model MIKESHE that showed that runoff and water table level are sensitive to global warming, and that the sustained warming trends can be expected to decrease stream discharge and lower the mean water table depth. The spatially-explicit biogeochemical model Forest-DNDC, validated using biomass measurements from the watersheds, was used to assess carbon dynamics in response to high resolution hydrologic observation data and simulation results. The simulations showed that the long-term spatiotemporal carbon dynamics, including biomass and fluxes of soil carbon dioxide and methane were highly regulated by disturbance regimes, climatic conditions and water table depth. The utility of linked-modeling framework demonstrated here to assess biogeochemical responses at the watershed scale suggests applications for assessing the consequences of climate change within an urbanizing forested landscape. The approach may also be applicable for validating large

EOP and scale from continuous VLBI observing: CONT campaigns to future VGOS networks

NASA Astrophysics Data System (ADS)

MacMillan, D. S.

2017-07-01

Continuous (CONT) VLBI campaigns have been carried out about every 3 years since 2002. The basic idea of these campaigns is to acquire state-of-the-art VLBI data over a continuous time period of about 2 weeks to demonstrate the highest accuracy of which the current VLBI system is capable. In addition, these campaigns support scientific studies such as investigations of high-resolution Earth rotation, reference frame stability, and daily to sub-daily site motions. The size of the CONT networks and the observing data rate have increased steadily since 1994. Performance of these networks based on reference frame scale precision and polar motion/LOD comparison with global navigation satellite system (GNSS) earth orientation parameters (EOP) has been substantially better than the weekly operational R1 and R4 series. The precisions of CONT EOP and scale have improved by more than a factor of two since 2002. Polar motion precision based on the WRMS difference between VLBI and GNSS for the most recent CONT campaigns is at the 30 μas level, which is comparable to that of GNSS. The CONT campaigns are a natural precursor to the planned future VLBI observing networks, which are expected to observe continuously. We compare the performance of the most recent CONT campaigns in 2011 and 2014 with the expected performance of the future VLBI global observing system network using simulations. These simulations indicate that the expected future precision of scale and EOP will be at least 3 times better than the current CONT precision.

Long-Term Stability of the SGA-WZ Strapdown Airborne Gravimeter

PubMed Central

Cai, Shaokun; Zhang, Kaidong; Wu, Meiping; Huang, Yangming

2012-01-01

Accelerometers are one of the most important sensors in a strapdown airborne gravimeter. The accelerometer's drift determines the long-term accuracy of the strapdown inertial navigation system (SINS), which is the primary and most critical component of the strapdown airborne gravimeter. A long-term stability test lasting 104 days was conducted to determine the characteristics of the strapdown airborne gravimeter's long-term drift. This stability test was based on the first set of strapdown airborne gravimeters built in China, the SGA-WZ. The test results reveal a quadratic drift in the strapdown airborne gravimeter data. A drift model was developed using the static data in the two end sections, and then this model was used to correct the test data. After compensating for the drift, the drift effect improved from 70 mGal to 3.46 mGal with a standard deviation of 0.63 mGal. The quadratic curve better reflects the drift's real characteristics. In comparison with other methodologies, modelling the drift as a quadratic curve was shown to be more appropriate. Furthermore, this method allows the drift to be adjusted throughout the course of the entire campaign. PMID:23112647

Multi-Scale Observation and Modelling of Energy and Matter Exchange in the Atmospheric Boundary-Layer (ScaleX Campaigns)

NASA Astrophysics Data System (ADS)

Zeeman, M. J.; Wolz, K.; Adler, B.; Brenner, C.; De Roo, F.; Emeis, S.; Kalthoff, N.; Mauder, M.; Schäfer, K.; Wohlfahrt, G.; Zhao, P.

2016-12-01

We investigated biosphere-atmosphere exchange processes in relation to the atmospheric boundary-layer (ABL) flow in a shallow valley. Land-use heterogeneity and topography can force local atmospheric flow patterns, including local circulations. Such flow patterns can impair current techniques for the quantification and source attribution of surface-exchange fluxes due to flux-divergence, advection and decoupling. Wind field, temperature and humidity structures in the ABL were observed in high resolution with spatially distributed observations in a 1 km3 experimental domain. Remote-sensing observations of wind, temperature and particles in the ABL (Raman-lidar; RASS; ceilometer; microwave radiometer; 3D Doppler-lidar) were combined with a high-resolution network of in-situ observations that included vertical and horizontal profiles of wind, temperature, carbon dioxide, methane and water vapor concentrations. The experiments were co-located with the long-term eddy covariance (EC) observatory Fendt (DE-Fen; ICOS, TERENO) and were part of international cooperative efforts in 2015 and 2016 (the ScaleX campaigns). The gathered experimental data offers a scale-transcending insight in local flow patterns in mountainous terrain and their influence on surface-exchange fluxes of energy and matter as observed by EC and flux-gradient methodology. In addition, the data is used for validation of Large-Eddy Simulations in complex terrain using PALM-LES. Within this modelling framework, virtual measurements are conducted to further assess the importance of three-dimensional advective and horizontal turbulent transport terms.

[Long-term observation of 920 porcelain fused to metal prostheses].

PubMed

Jiang, Yong-Lin; Sun, Jian; Weng, Wei-Min; Zhang, Fu-Qiang

2006-10-01

To evaluate the long-term clinical results of porcelain fused to metal prostheses. Since January 1995, 920 porcelain fused to metal prostheses were fabricated. The long-term outcome were evaluated according to the condition of the prosthese, abutment and the periodontal tissue in the respects of successful rate and causes of failure. 74 patients were found to be during the follow up period, including 36 anterior crowns (46 units), 18 posterior crowns (22 units), 12 percentage of anterior bridges and 8 posterior bridges. The overall failure rate was 8.04%, 4.84% for crown, 8.77% for bridge. The failed prostheses was 5.39%. Porcelain fused to metal prostheses is an ideal method for restoration. The standard process both for the clinician and the technician must be obeyed to improve the success rate.

Implementing CUAHSI and SWE observation data models in the long-term monitoring infrastructure TERENO

NASA Astrophysics Data System (ADS)

Klump, J. F.; Stender, V.; Schroeder, M.

2013-12-01

Terrestrial Environmental Observatories (TERENO) is an interdisciplinary and long-term research project spanning an Earth observation network across Germany. It includes four test sites within Germany from the North German lowlands to the Bavarian Alps and is operated by six research centers of the Helmholtz Association. The contribution by the participating research centers is organized as regional observatories. The challenge for TERENO and its observatories is to integrate all aspects of data management, data workflows, data modeling and visualizations into the design of a monitoring infrastructure. TERENO Northeast is one of the sub-observatories of TERENO and is operated by the German Research Centre for Geosciences GFZ in Potsdam. This observatory investigates geoecological processes in the northeastern lowland of Germany by collecting large amounts of environmentally relevant data. The success of long-term projects like TERENO depends on well-organized data management, data exchange between the partners involved and on the availability of the captured data. Data discovery and dissemination are facilitated not only through data portals of the regional TERENO observatories but also through a common spatial data infrastructure TEODOOR. TEODOOR bundles the data, provided by the different web services of the single observatories, and provides tools for data discovery, visualization and data access. The TERENO Northeast data infrastructure integrates data from more than 200 instruments and makes the data available through standard web services. Data are stored following the CUAHSI observation data model in combination with the 52° North Sensor Observation Service data model. The data model was implemented using the PostgreSQL/PostGIS DBMS. Especially in a long-term project, such as TERENO, care has to be taken in the data model. We chose to adopt the CUAHSI observational data model because it is designed to store observations and descriptive information (metadata

Long-term changes in the South China Sea summer monsoon revealed by station observations of the Xisha Islands

NASA Astrophysics Data System (ADS)

Liang, Jianyin; Yang, Song; Li, Cunhui; Li, Xia

2007-05-01

The authors depict the long-term changes in the South China Sea (SCS) summer monsoon using observational data of the Xisha Islands. The SCS monsoon is an important component of the Asian monsoon system, and its long-term changes have seldom been explored because of the unavailability of reliable data. The daily Xisha station observations provide an important source of information for understanding the changes in the monsoon. The intensity of the SCS summer monsoon measured by kinetic energy decreased significantly from 1958-1977 to 1978-2004. This change in monsoon was mainly caused by the weakening of the meridional component of lower tropospheric winds, and the weakening in the mean flow was signaled by decreased frequency of strong southerlies (6 m s-1 and above) of the daily winds. The weakening of the monsoon was also associated with increases in sea surface temperature and surface and lower tropospheric air temperatures over SCS, which occurred more frequently when daily surface temperature reaches 29°C and higher. The long-term warming of the lower troposphere was accompanied by cooling at the upper troposphere, destabilizing the local atmosphere. However, from 1958-1977 to 1978-2004, the long-term change in Xisha precipitation tended to decrease; furthermore, in fact, the station precipitation became less variable. Thus besides local air-sea interaction, large-scale atmospheric forcing also plays an important role in causing the long-term change of the Xisha precipitation. Indeed, the warming of Xisha was linked to large-scale warming in the tropics including SCS and was associated with smaller thermal contrast between the Asian continent and the surrounding oceans, which weakened monsoon circulation.

Long Term Association of Tropospheric Trace gases over Pakistan by exploiting satellite observations and development of Econometric Regression based Model

NASA Astrophysics Data System (ADS)

Zeb, Naila; Fahim Khokhar, Muhammad; Khan, Saud Ahmed; Noreen, Asma; Murtaza, Rabbia

2017-04-01

Air pollution is the expected key environmental issue of Pakistan as it is ranked among top polluted countries in the region. Ongoing rapid economic growth without any adequate measures is leading to worst air quality over time. The study aims to monitor long term atmospheric composition and association of trace gases over Pakistan. Tropospheric concentrations of CO, TOC, NO2 and HCHO derived from multiple satellite instruments are used for study from year 2005 to 2014. The study will provide first database for tropospheric trace gases over Pakistan. Spatio-temporal assessment identified hotspots and possible sources of trace gases over the Pakistan. High concentrations of trace gases are mainly observed over Punjab region, which may be attributed to its metropolitan importance. It is the major agricultural, industrialized and urbanized (nearly 60 % of the Pakistan's population) sector of the country. The expected sources are the agricultural fires, biomass/fossil fuel burning for heating purposes, urbanization, industrialization and meteorological variations. Seasonal variability is observed to explore seasonal patterns over the decade. Well defined seasonal cycles of trace gases are observed over the whole study period. The observed seasonal patterns also showed some noteworthy association among trace gases, which is further explored by different statistical tests. Seasonal Mann Kendall test is applied to test the significance of trend in series whereas correlation is carried out to measure the strength of association among trace gases. Strong correlation is observed for trace gases especially between CO and TOC. Partial Mann Kendall test is used to ideally identify the impact of each covariate on long term trend of CO and TOC by partialling out each correlating trace gas (covariate). It is observed that TOC, NO2 and HCHO has significant impact on long term trend of CO whereas, TOC critically depends on NO2 concentrations for long term increase over the region

The exceptional recent warming signal in a long-term central-German observation site

NASA Astrophysics Data System (ADS)

Hoy, Andreas; Schönwiese, Christian-Dietrich

2017-04-01

The long-term temperature measurements of Frankfurt/Main represent a scientifically highly valuable source for investigating climatic changes in central Germany and beyond. Annual data are available since 1758 and daily observations since 1870. The 258 year long annual time series is homogenised and recalculated to the airport location outside of Frankfurt/Main city. In a first step, impacts of site changes and urbanisation effects are discussed comparing the five different inner-city monitoring points and the airport location after WWII. We show that site changes affect both extreme and average temperatures, and that they may be considerable even for small relocations. Urbanisation effects are visible all year long and stronger for minimum than maximum temperatures. Annual temperature observations show slightly decreasing temperatures until the 1840s. This development is then replaced by an increasing trend overlain by decadal-scale and yearly fluctuations. Nevertheless, until the 1980s shifting 30-year-means only fluctuate between 8.54 °C in 1829-1858 and 9.58 °C in 1948-1977. However, recent years more than doubled the 1 K spread between the coldest and warmest period, with an average of 10.82 °C in 1986-2015. In addition, this 30-year period was warmer than any single year before 1990. Record-cold calendar days almost disappeared since 1988, while record-warm calendar days appeared about three times more often than statistically expectable. Strong warming was observed year-round, only September and October showed more moderate trends.

Development of compact long-term broadband ocean bottom seismometer for seafloor observation of slow earthquakes

NASA Astrophysics Data System (ADS)

Yamashita, Y.; Shinohara, M.; Yamada, T.; Shiobara, H.

2017-12-01

It is important to understand coupling between plates in a subduction zone for studies of earthquake generation. Recently low frequency tremor and very low frequency earthquake (VLFE) were discovered in plate boundary near a trench. These events (slow earthquakes) in shallow plate boundary should be related to slow slip on a plate boundary. For observation of slow earthquakes, Broad Band Ocean Bottom Seismometer (BBOBS) is useful, however a number of BBOBSs are limited due to cost. On the other hand, a number of Long-term OBSs (LT-OBSs) with recording period of one year are available. However, the LT-OBS has seismometer with a natural period of 1 second. Therefore frequency band of observation is slightly narrow for slow earthquakes. Therefore we developed a compact long-term broad-band OBS by replacement of the seismic sensor of the LT-OBSs to broadband seismometer.We adopted seismic sensor with natural period of 20 seconds (Trillium Compact Broadband Seismometer, Nanometrics). Because tilt of OBS on seafloor can not be controlled due to free-fall, leveling system for seismic sensor is necessary. The broadband seismic senor has cylinder shape with diameter of 90 mm and height of 100 mm, and the developed levelling system can mount the seismic sensor with no modification of shape. The levelling system has diameter of 160 mm and height of 110 mm, which is the same size as existing levelling system of the LT-OBS. The levelling system has two horizontal axes and each axis is driven by motor. Leveling can be performed up to 20 degrees by using micro-processor (Arduino). Resolution of levelling is less than one degree. The system immediately starts leveling by the power-on of controller. After levelling, the the seismic senor is powered and the controller records angles of levelling to SD RAM. Then the controller is shut down to consume no power. Compact long-term broadband ocean bottom seismometer is useful for observation of slow earthquakes on seafloor. In addition

Assessing the Ability of Instantaneous Aircraft and Sonde Measurements to Characterize Climatological Means and Long-Term Trends in Tropospheric Composition

NASA Technical Reports Server (NTRS)

Murray, Lee T.; Fiore, Arlene M.

2014-01-01

Over four decades of measurements exist that sample the 3-D composition of reactive trace gases in the troposphere from approximately weekly ozone sondes, instrumentation on civil aircraft, and individual comprehensive aircraft field campaigns. An obstacle to using these data to evaluate coupled chemistry-climate models (CCMs)the models used to project future changes in atmospheric composition and climateis that exact space-time matching between model fields and observations cannot be done, as CCMs generate their own meteorology. Evaluation typically involves averaging over large spatiotemporal regions, which may not reflect a true average due to limited or biased sampling. This averaging approach generally loses information regarding specific processes. Here we aim to identify where discrete sampling may be indicative of long-term mean conditions, using the GEOS-Chem global chemical-transport model (CTM) driven by the MERRA reanalysis to reflect historical meteorology from 2003 to 2012 at 2o by 2.5o resolution. The model has been sampled at the time and location of every ozone sonde profile available from the Would Ozone and Ultraviolet Radiation Data Centre (WOUDC), along the flight tracks of the IAGOSMOZAICCARABIC civil aircraft campaigns, as well as those from over 20 individual field campaigns performed by NASA, NOAA, DOE, NSF, NERC (UK), and DLR (Germany) during the simulation period. Focusing on ozone, carbon monoxide and reactive nitrogen species, we assess where aggregates of the in situ data are representative of the decadal mean vertical, spatial and temporal distributions that would be appropriate for evaluating CCMs. Next, we identically sample a series of parallel sensitivity simulations in which individual emission sources (e.g., lightning, biogenic VOCs, wildfires, US anthropogenic) have been removed one by one, to assess where and when the aggregated observations may offer constraints on these processes within CCMs. Lastly, we show results of an

Effectiveness and cost-effectiveness of an awareness campaign for colorectal cancer: a mathematical modeling study.

PubMed

Whyte, Sophie; Harnan, Susan

2014-06-01

A campaign to increase the awareness of the signs and symptoms of colorectal cancer (CRC) and encourage self-presentation to a GP was piloted in two regions of England in 2011. Short-term data from the pilot evaluation on campaign cost and changes in GP attendances/referrals, CRC incidence, and CRC screening uptake were available. The objective was to estimate the effectiveness and cost-effectiveness of a CRC awareness campaign by using a mathematical model which extrapolates short-term outcomes to predict long-term impacts on cancer mortality, quality-adjusted life-years (QALYs), and costs. A mathematical model representing England (aged 30+) for a lifetime horizon was developed. Long-term changes to cancer incidence, cancer stage distribution, cancer mortality, and QALYs were estimated. Costs were estimated incorporating costs associated with delivering the campaign, additional GP attendances, and changes in CRC treatment. Data from the pilot campaign suggested that the awareness campaign caused a 1-month 10 % increase in presentation rates. Based on this, the model predicted the campaign to cost £5.5 million, prevent 66 CRC deaths and gain 404 QALYs. The incremental cost-effectiveness ratio compared to "no campaign" was £13,496 per QALY. Results were sensitive to the magnitude and duration of the increase in presentation rates and to disease stage. The effectiveness and cost-effectiveness of a cancer awareness campaign can be estimated based on short-term data. Such predictions will aid policy makers in prioritizing between cancer control strategies. Future cost-effectiveness studies would benefit from campaign evaluations reporting as follows: data completeness, duration of impact, impact on emergency presentations, and comparison with non-intervention regions.

Evaluation of the crustal deformations in the northern region of Lake Nasser (Egypt) derived from 8 years of GPS campaign observations

NASA Astrophysics Data System (ADS)

Rayan, A.; Fernandes, R. M. S.; Khalil, H. A.; Mahmoud, S.; Miranda, J. M.; Tealab, A.

2010-04-01

The proper evaluation of crustal deformations in the Aswan (Egypt) region is crucial due to the existence of one major artificial structure: the Aswan High Dam. This construction induced the creation of one of the major artificial lakes: Lake Nasser, which has a surface area of about 5200 km 2 with a maximum capacity of 165 km 3. The lake is nearly 550 km long (more than 350 km within Egypt and the remainder in Sudan) and 35 km across at its widest point. Great attention has focused on this area after the November 14, 1981 earthquake ( ML = 5.7), with its epicenter southwest of the High Dam. In order to evaluate the present-day kinematics of the region, its relationship with increasing seismicity, and the possible influence of the Aswan High Dam operation, a network of 11 GPS sites was deployed in the area. This network has been reobserved every year since 2000 in campaign style. We present here the results of the analysis of the GPS campaign time-series. These time-series are already long enough to derive robust solutions for the motions of these stations. The computed trends are analyzed within the framework of the geophysical and geological settings of this region. We show that the observed displacements are significant, pointing to a coherent intraplate extensional deformation pattern, where some of the major faults (e.g., dextral strike-slip Kalabsha fault and normal Dabud fault) correspond to gradients of the surface deformation field. We also discuss the possible influence of the water load on the long-term deformation pattern.

A Long-Term Psychological Observation in an Adolescent Affected with Gardner Diamond Syndrome

PubMed Central

Bizzi, Fabiola; Sciarretta, Lucia; D’Alessandro, Matteo; Picco, Paolo

2016-01-01

Gardner-Diamond syndrome (GDS) is an uncommon disease clinically characterized by a wide spectrum of psycho-emotive symptoms associated with painful ecchymoses/purpuric lesions and positivity of auto-erythrocyte sensitization skin test. Herein, a perspective clinical and psychological observation of an adolescent GDS is firstly reported focusing on her psychological features long-term monitored for a 1-year period. The administration of a standardized tools battery allowed us to define psychological features of the young patient over time and to monitored clinical course and response to treatment. PMID:27011410

World-wide amateur observations

NASA Astrophysics Data System (ADS)

Eversberg, T.; Aldoretta, E. J.; Knapen, J. H.; Moffat, A. F. J.; Morel, T.; Ramiaramanantsoa, T.; Rauw, G.; Richardson, N. D.; St-Louis, N.; Teodoro, M.

For some years now, spectroscopic measurements of massive stars in the amateur domain have been fulfilling professional requirements. Various groups in the northern and southern hemispheres have been established, running successful professional-amateur (ProAm) collaborative campaigns, e.g., on WR, O and B type stars. Today high quality data (echelle and long-slit) are regularly delivered and corresponding results published. Night-to-night long-term observations over months to years open a new opportunity for massive-star research. We introduce recent and ongoing sample campaigns (e.g. ɛ Aur, WR 134, ζ Pup), show respective results and highlight the vast amount of data collected in various data bases. Ultimately it is in the time-dependent domain where amateurs can shine most.

Long-term tropospheric and lower stratospheric ozone variations from ozonesonde observations

NASA Technical Reports Server (NTRS)

London, J.; Liu, S. C.

1992-01-01

An analysis is presented of the long-term mean pressure-latitude seasonal distribution of tropospheric and lower stratospheric ozone for the four seasons covering, in part, over 20 years of ozonesonde data. The observed patterns show minimum ozone mixing ratios in the equatorial and tropical troposphere except in regions where net photochemical production is dominant. In the middle and upper troposphere, and low stratosphere to 50 mb, ozone increases from the tropics to subpolar latitudes of both hemispheres. In mid stratosphere, the ozone mixing ratio is a maximum over the tropics. The observed vertical ozone gradient is small in the troposphere but increases rapidly above the tropopause. The amplitude of the annual variation increases from a minimum in the tropics to a maximum in polar regions. Also, the amplitude increases with height at all latitudes up to about 30 mb where the phase of the annual variation changes abruptly. The phase of the annual variation is during spring in the boundary layer, summer in mid troposphere, and spring in the upper troposhere and lower stratosphere.

Short- and Long-Term Feedbacks on Vegetation Water Use: Unifying Evidence from Observations and Modeling

NASA Astrophysics Data System (ADS)

Mackay, D. S.

2001-05-01

Recent efforts to measure and model the interacting influences of climate, soil, and vegetation on soil water and nutrient dynamics have identified numerous important feedbacks that produce nonlinear responses. In particular, plant physiological factors that control rates of transpiration respond to soil water deficits and vapor pressure deficits (VPD) in the short-term, and to climate, nutrient cycling and disturbance in the long-term. The starting point of this presentation is the observation that in many systems, in particular forest ecosystems, conservative water use emerges as a result of short-term closure of stomata in response to high evaporative demand, and long-term vegetative canopy development under nutrient limiting conditions. Evidence for important short-term controls is presented from sap flux measurements of stand transpiration, remote sensing, and modeling of transpiration through a combination of physically-based modeling and Monte Carlo analysis. A common result is a strong association between stomatal conductance (gs) and the negative evaporative gain (∂ gs/∂ VPD) associated with the sensitivity of stomatal closure to rates of water loss. The importance of this association from the standpoint of modeling transpiration depends on the degree of canopy-atmosphere coupling. This suggests possible simplifications to future canopy component models for use in watershed and larger-scale hydrologic models for short-term processes. However, further results are presented from theoretical modeling, which suggest that feedbacks between hydrology and vegetation in current long-term (inter-annual to century) models may be too simple, as they do not capture the spatially variable nature of slow nutrient cycling in response to soil water dynamics and site history. Memory effects in the soil nutrient pools can leave lasting effects on more rapid processes associated with soil, vegetation, atmosphere coupling.

Long Term Seismic Observation in Mariana by OBSs : Double Seismic Zone and Upper Mantle Structure

NASA Astrophysics Data System (ADS)

Shiobara, H.; Sugioka, H.; Mochizuki, K.; Oki, S.; Kanazawa, T.; Fukao, Y.; Suyehiro, K.

2005-12-01

In order to obtain the deep arc structural image of Mariana, a large-scale seismic observation by using 58 long-term ocean bottom seismometers (LTOBS) had been performed from June 2003 until April 2004, which is a part of the MARGINS program funded by the NSF. Prior to this observation, a pilot long-term seismic array observation was conducted in the same area by using 10 LTOBSs from Oct. 2001 until Feb. 2003. At that time, 8 LTOBSs were recovered but one had no data. Recently, 2 LTOBSs, had troubles in the releasing, were recovered by the manned submersible (Shinkai 6500, Jamstec) for the research of the malfunction in July 2005. By using all 9 LTOBS's data, those are about 11 months long, hypocenter determination was performed and more than 3000 local events were found. Even with the 1D velocity structure based on the iasp91 model, double seismic zones and a systematic shift of epicenters between the PDE and this study were observed. To investigate the detail of hypocenter distribution and the 3D velocity structure, the DD inversion (tomoDD: Zhang and Thurber, 2003) was applied for this data set with the 1D structure initial model except for the crust, which has been surveyed by using a dense airgun-OBS system (Takahashi et al., 2003). The result of relocated hypocenters shows clear double seismic zones until about 200 km depth, a high activity area around the fore-arc serpentine sea-mount, the Big Blue, and a lined focuses along the current ridge axis in the back-arc basin, and the result of the tomography shows a image of subducting slab and a low-Vs region below the same sea-mount mentioned. The wedge mantle structure was not clearly resolved due to the inadequate source-receiver coverage, which will be done in the recent experiment.

Long-term monitoring of persistent organic pollutants (POPs) at the Norwegian Troll station in Dronning Maud Land, Antarctica

NASA Astrophysics Data System (ADS)

Kallenborn, R.; Breivik, K.; Eckhardt, S.; Lunder, C. R.; Manø, S.; Schlabach, M.; Stohl, A.

2013-03-01

A first long-term monitoring of selected persistent organic pollutants (POPs) in Antarctic air has been conducted at the Norwegian Research station Troll (Dronning Maud Land). As target contaminants 32 PCB congeners, a- and g-hexachlorocyclohexane (HCH), trans- and cis-chlordane, trans- and cis-nonachlor, p,p'- and o,p-DDT, DDD, DDE as well as hexachlorobenzene (HCB) were selected. The monitoring program with weekly samples taken during the period 2007-2010 was coordinated with the parallel program at the Norwegian Arctic monitoring site (Zeppelin mountain, Ny-Ålesund, Svalbard) in terms of priority compounds, sampling schedule as well as analytical methods. The POP concentration levels found in Antarctica were considerably lower than Arctic atmospheric background concentrations. Similar as observed for Arctic samples, HCB is the predominant POP compound with levels of around 22 pg m-3 throughout the entire monitoring period. In general, the following concentration distribution was found for the Troll samples analyzed: HCB > Sum HCH > Sum PCB > Sum DDT > Sum chlordanes. Atmospheric long-range transport was identified as a major contamination source for POPs in Antarctic environments. Several long-range transport events with elevated levels of pesticides and/or compounds with industrial sources were identified based on retroplume calculations with a Lagrangian particle dispersion model (FLEXPART). The POP levels determined in Troll air were compared with 1 concentrations found in earlier measurement campaigns at other Antarctic research stations from the past 18 yr. Except for HCB for which similar concentration distributions were observed in all sampling campaigns, concentrations in the recent Troll samples were lower than in samples collected during the early 1990s. These concentration reductions are obviously a direct consequence of international regulations restricting the usage of POP-like chemicals on a worldwide scale.

Towards Improved Understanding of Drought and Drought Impacts from Long Term Earth Observation Records

NASA Astrophysics Data System (ADS)

Champagne, C.; Wang, S.; Liu, J.; Hadwen, T. A.

2017-12-01

Drought is a complex natural disaster, which often emerges slowly, but can occur at various time scales and have impacts that are not well understood. Long term observations of drought intensity and frequency are often quantified from precipitation and temperature based indices or modelled estimates of soil water storage. The maturity of satellite based observations has created the potential to enhance the understanding of drought and drought impacts, particularly in regions where traditional data sets are limited by remoteness or inaccessibility, and where drought processes are not well-quantified by models. Long term global satellite data records now provide observations of key hydrological variables, including evaporation modelled from thermal sensors, soil moisture from microwave sensors, ground water from gravity sensors and vegetation condition that can be modelled from optical sensors. This study examined trends in drought frequency, intensity and duration over diverse ecoregions in Canada, including agricultural, grassland, forested and wetland areas. Trends in drought were obtained from the Canadian Drought Monitor as well as meteorological based indices from weather stations, and evaluated against satellite derived information on evaporative stress (Anderson et al. 2011), soil moisture (Champagne et al. 2015), terrestrial water storage (Wang and Li 2016) and vegetation condition (Davidson et al. 2009). Data sets were evaluated to determine differences in how different sensors characterize the hydrology and impacts of drought events from 2003 to 2016. Preliminary results show how different hydrological observations can provide unique information that can tie causes of drought (water shortages resulting from precipitation, lack of moisture storage or evaporative stress) to impacts (vegetation condition) that hold the potential to improve the understanding and classification of drought events.

Changes in long-term eruption dynamics at Santiaguito, Guatemala: Observations from seismic data

NASA Astrophysics Data System (ADS)

Lamb, O. D.; Lavallée, Y.; De Angelis, S.; Lamur, A.; Hornby, A. J.; von Aulock, F. W.; Kendrick, J. E.; Chigna, G.; Rietbrock, A.

2016-12-01

Santiaguito (Guatemala) is an ideal laboratory for the study of the eruption dynamics of long-lived silicic eruptions. Here we present seismic observations of ash-and-gas explosions recorded between November 2014 and June 2016 during a multi-disciplinary experiment by the University of Liverpool. The instruments, deployed around the active dome complex between 0.5 to 7 km from the vent, included 5 broadband and 6 short-period seismometers, as well as 5 infrasound sensors. The geophysical data is complemented by thermal images, optical images from a UAV, and geochemical measurements of erupted material. Regular, small-to-moderate sized explosions from the El Caliente dome at Santiaguito have been common since at least the early 1970s. However, in 2015, a shift in character took place in terms of the regularity and magnitude of the explosions. Explosions became larger and less regular, and often accompanied by pyroclastic density currents. The larger explosions have caused a major morphological change at the vent, as a rubble-filled vent was replaced by a crater of 150 m depth. This shift in behaviour likely represents a change in the eruptive mechanism in the upper conduit beneath the Caliente vent, possibly triggered by processes at a greater depth in the volcanic system. This experiment represents a unique opportunity to use multi-disciplinary research to help understand the long-term eruptive dynamics of lava dome eruptions. Our observations may have implications for hazard assessment not only at Santiaguito, but at many other volcanic systems worldwide.

Long-Term Memory Performance in Adult ADHD.

PubMed

Skodzik, Timo; Holling, Heinz; Pedersen, Anya

2017-02-01

Memory problems are a frequently reported symptom in adult ADHD, and it is well-documented that adults with ADHD perform poorly on long-term memory tests. However, the cause of this effect is still controversial. The present meta-analysis examined underlying mechanisms that may lead to long-term memory impairments in adult ADHD. We performed separate meta-analyses of measures of memory acquisition and long-term memory using both verbal and visual memory tests. In addition, the influence of potential moderator variables was examined. Adults with ADHD performed significantly worse than controls on verbal but not on visual long-term memory and memory acquisition subtests. The long-term memory deficit was strongly statistically related to the memory acquisition deficit. In contrast, no retrieval problems were observable. Our results suggest that memory deficits in adult ADHD reflect a learning deficit induced at the stage of encoding. Implications for clinical and research settings are presented.

A preliminary experiment for the long-term regional reanalysis over Japan assimilating conventional observations with NHM-LETKF

NASA Astrophysics Data System (ADS)

Fukui, Shin; Iwasaki, Toshiki; Saito, Kazuo; Seko, Hiromu; Kunii, Masaru

2016-04-01

Several long-term global reanalyses have been produced by major operational centres and have contributed to the advance of weather and climate researches considerably. Although the horizontal resolutions of these global reanalyses are getting higher partly due to the development of computing technology, they are still too coarse to reproduce local circulations and precipitation realistically. To solve this problem, dynamical downscaling is often employed. However, the forcing from lateral boundaries only cannot necessarily control the inner fields especially in long-term dynamical downscaling. Regional reanalysis is expected to overcome the difficulty. To maintain the long-term consistency of the analysis quality, it is better to assimilate only the conventional observations that are available in long period. To confirm the effectiveness of the regional reanalysis, some assimilation experiments are performed. In the experiments, only conventional observations (SYNOP, SHIP, BUOY, TEMP, PILOT, TC-Bogus) are assimilated with the NHM-LETKF system, which consists of the nonhydrostatic model (NHM) of the Japan Meteorological Agency (JMA) and the local ensemble transform Kalman filter (LETKF). The horizontal resolution is 25 km and the domain covers Japan and its surroundings. Japanese 55-year reanalysis (JRA-55) is adopted as the initial and lateral boundary conditions for the NHM-LETKF forecast-analysis cycles. The ensemble size is 10. The experimental period is August 2014 as a representative of warm season for the region. The results are verified against the JMA's operational Meso-scale Analysis, which is produced with assimilating observation data including various remote sensing observations using a 4D-Var scheme, and compared with those of the simple dynamical downscaling experiment without data assimilation. Effects of implementation of lateral boundary perturbations derived from an EOF analysis of JRA-55 over the targeted domain are also examined. The comparison

Geocoronal hydrogen studies using Fabry Perot interferometers, part 2: Long-term observations

NASA Astrophysics Data System (ADS)

Nossal, S. M.; Mierkiewicz, E. J.; Roesler, F. L.; Reynolds, R. J.; Haffner, L. M.

2006-09-01

Long-term data sets are required to investigate sources of natural variability in the upper atmosphere. Understanding the influence of sources of natural variability such as the solar cycle is needed to characterize the thermosphere + exosphere, to understand coupling processes between atmospheric regions, and to isolate signatures of natural variability from those due to human-caused change. Multi-year comparisons of thermospheric + exospheric Balmer α emissions require cross-calibrated and well-understood instrumentation, a stable calibration source, reproducible observing conditions, separation of the terrestrial from the Galactic emission line, and consistent data analysis accounting for differences in viewing geometry. We discuss how we address these criteria in the acquisition and analysis of a mid-latitude geocoronal Balmer α column emission data set now spanning two solar cycles and taken mainly from Wisconsin and Kitt Peak, Arizona. We also discuss results and outstanding challenges for increasing the accuracy and use of these observations.

DOC and nitrate export linked to dominant rainfall-runoff processes, end-members and seasonality - a long-term high frequency measurement campaign

NASA Astrophysics Data System (ADS)

Schwab, M. P.; Klaus, J.; Pfister, L.; Weiler, M.

2016-12-01

Over the past decades, stream sampling protocols for hydro-geochemical parameters were often limited by logistical and technological constraints. While long-term monitoring protocols were typically based on weekly sampling intervals, high frequency sampling was commonly limited to a few single events. In this contribution, we combined high frequency and long-term measurements to understand DOC and nitrate dynamics in a forest headwater for different runoff events and seasons. Our study area is the forested Weierbach catchment (0.47 km2) in Luxembourg, where the fractured schist bedrock is covered by cambisol soils. The runoff response is characterized by a double peak behaviour. The first peak occurs during or right after a rainfall event triggered by fast near surface runoff generation processes, while a second delayed peak lasts several days and is generated by subsurface flow. This second peak occurs only if a distinct storage threshold of the catchment is exceeded. Our observations were carried out with a field deployable UV-Vis spectrometer measuring DOC and nitrate concentrations in-situ at 15 min intervals for more than two years. In addition, a long-term validation was carried out with data obtained from the analysis of water collected with grab samples. The long-term, high-frequency measurements allowed us to calculate a complete and detailed balance of DOC and nitrate export over two years. Transport behaviour of the DOC and nitrate showed different dynamics between the first and second hydrograph peaks. DOC is mainly exported during the first peaks, while nitrate is mostly exported during the delayed second peaks. Biweekly end-member measurement of soil and groundwater over several years enables us to link the behaviour of DOC and nitrate export to various end-members in the catchment. Altogether, the long-term and high-frequency time series provides the opportunity to study DOC and nitrate export processes without having to just rely only on either a

Long-Term Neurological Outcomes in West Nile Virus–Infected Patients: An Observational Study

PubMed Central

Weatherhead, Jill E.; Miller, Vicki E.; Garcia, Melissa N.; Hasbun, Rodrigo; Salazar, Lucrecia; Dimachkie, Mazen M.; Murray, Kristy O.

2015-01-01

The Houston West Nile Cohort (HWNC) was founded in 2002 when West Nile virus (WNV) reached Houston, TX. The long-term outcomes following WNV infection are still mostly unknown, though neurological abnormalities up to 1 year postinfection have been documented. We report an observational study of neurological abnormalities at 1–3 and 8–11 years following WNV infection in the HWNC. We conducted standard neurological examinations at two separate time points to assess changes in neurological status over time. The majority of patients (86%, 30/35) with encephalitis had abnormal neurological exam findings at the time of the first assessment compared with uncomplicated fever (27%, 3/11) and meningitis (36%, 5/14) cases. At the time of the second assessment, 57% (4/7) of West Nile fever (WNF), 33% (2/6) of West Nile meningitis (WNM), and 36% (5/14) of West Nile encephalitis (WNE) had developed new neurological complications. The most common abnormalities noted were tandem gait, hearing loss, abnormal reflexes, and muscle weakness. Long-term neurological abnormalities were most commonly found in patients who experienced primary WNV encephalitis. New abnormalities may develop over time regardless of initial clinical infection. Future studies should aim to differentiate neurological consequences due to WNV neuroinvasive infection versus neurological decline related to comorbid conditions. PMID:25802426

Life cycles of traumatized teeth: long-term observations from a cohort of dental trauma victims - series 2.

PubMed

Heithersay, G S

2016-09-01

In this the second of a series of life cycles of dental trauma victims, the short and particularly long-term responses of four survivors of either multiple luxation injuries or avulsions have been documented over periods varying up to 41 years. The development of ankylosis, either in the short or longer term post trauma, proved a common feature in the series and management strategies have been outlined. External invasive resorption was also identified as a complicating response for which the topical application of trichloracetic acid, intracanal dressing and root canal obturation proved effective in resorption management. Long-term observations indicate that some compromised teeth can be functionally and aesthetically retained for extended periods, but follow-up examinations are important so that treatment interventions can be implemented if adverse responses are diagnosed. © 2016 Australian Dental Association.

Geodesic and hydrogeophysic long term observations in the Durzon karstic aquifer (Larzac, France)

NASA Astrophysics Data System (ADS)

Le Moigne, Nicolas; Bayer, Roger; Boudin, Frederick; Champollion, Cedric; Chery, Jean; Collard, Philippe; Daignières, Marc; Deville, Sabrina; Doerflinger, Erik; Vernant, Philippe

2010-05-01

Karsts are generally characterized by high heterogeneity at all scales for both the water storage properties and the mode of water transport. The Durzon karst system is located in south of France and is characterized by a unsaturated zone of 100-150 m width. The water input is exclusively rainfall and draining occurs at the Durzon perennial spring in a karstic valley. The Durzon aquifer has been monitored by our group by different geophysical methods (gravimetry, tiltmetry, more details below) for several years. The present-day stage of the project is to setup long term observations to assess hydrological properties of the karst in a small area of 500m*500m with numerous caves (up to 100 m deep and more than 2 km of development). The observations are of four major types: - Continuous high frequency and high accuracy gravimetry: Gravimetric observations can be directly linked to the variations of water masses in the unsaturated zone. The iGrav™ Superconducting Gravity Meter from GWR (San Diego, USA) will be used to record continuous gravity variations and track water mass variations at a few millimeters level. The iGrav™ is a new SG model from GWR that has been simplified for portable and field operation, but retains the stability and precision of previous SGs. With a drift rate of less than 0.5 microGal/month and a virtually constant scale factory, the iGrav™ will provide a much higher stability and precision than can be achieved with mechanical spring-type gravity meters. - Water flux measurements (atmospheric and in-situ): A flux tower provides evapo-transpiration measurements (output) allowing complete budget calculation with the help of gravity (storage variations) and rainfall (input). An original measurement corresponds to the measure of the in-situ flow inside karstic caves (stalactites and underground river). - Tiltmetry: In situ (in caves) measurements are completed by long base silica tiltmeters. Tiltmeters are sensible to water storage in fractures

OBS development for long term observation in the Marmara Sea, NW Turkey

NASA Astrophysics Data System (ADS)

Takahashi, Narumi; Shimizu, Satoshi; Maekawa, Takuya; Kalafat, Dogan; Pinar, Ali; Citak, Seckin; Kaneda, Yoshiyuki

2015-04-01

We have carried out a collaboration study between Japan and Turkey since 2013, which is one of SATREPS projects, "Earthquake and Tsunami Disaster Mitigation in The Marmara Region and Disaster Education in Turkey". The main objective of this project is to reduce risk brought by earthquakes and tsunamis. In particular, the North Anatolian Fault system runs through the Marmara sea and it is expected that the seismic gap exists there according to past seismic studies. The details of seismicity distribution in the Marmara Sea is, however, still insufficient to construct fault model along the active faults. Therefore, we prepare ten ocean bottom seismographs (OBSs) to realize long term observation. We aim to identify size and depth of seismogenic zones using micro seismicity. In addition, we need to cover relative broad area from off-shore Istanbul city to the western end of the Marmara Sea. To clear these conditions, OBS specifications we need are high dynamic range and low instrument noise to observe micro seismicity, low electrical consumption to realize long term observation of over one year, high cost performance to cover the broad area for OBS installation, low cost implementation, and good operability to treat by relatively small number of persons. All items, which are three components velocity sensor, batteries, a recorder, a GPS receiver, a transponder and its transducer to control OBS retrieval, a flasher and a beacon, are installed in the 17 inches glass sphere. The natural frequency of the velocity sensor is 4.5 Hz and the frequency range of our OBS is from 4.5 Hz to 250 Hz. Data sampling is selectable among 100 Hz, 250 Hz and 500 Hz. Because our OBS is deployed by free fall, accuracy of the OBS clock is essentially one of important factors, and it is less than 0.1 ppm. And the resolution of A/D conversion performed on the recorder is 24 bit and we keep the dynamic range of over 135 dB. These data is stored on a semiconductor memory and the capacity is over

Long-term outcomes after severe shock.

PubMed

Pratt, Cristina M; Hirshberg, Eliotte L; Jones, Jason P; Kuttler, Kathryn G; Lanspa, Michael J; Wilson, Emily L; Hopkins, Ramona O; Brown, Samuel M

2015-02-01

Severe shock is a life-threatening condition with very high short-term mortality. Whether the long-term outcomes among survivors of severe shock are similar to long-term outcomes of other critical illness survivors is unknown. We therefore sought to assess long-term survival and functional outcomes among 90-day survivors of severe shock and determine whether clinical predictors were associated with outcomes. Seventy-six patients who were alive 90 days after severe shock (received ≥1 μg/kg per minute of norepinephrine equivalent) were eligible for the study. We measured 3-year survival and long-term functional outcomes using the Medical Outcomes Study 36-Item Short-Form Health Survey, the EuroQOL 5-D-3L, the Hospital Anxiety and Depression Scale, the Impact of Event Scale-Revised, and an employment instrument. We also assessed the relationship between in-hospital predictors and long-term outcomes. The mean long-term survival was 5.1 years; 82% (62 of 76) of patients survived, of whom 49 were eligible for follow-up. Patients who died were older than patients who survived. Thirty-six patients completed a telephone interview a mean of 5 years after hospital admission. The patients' Physical Functioning scores were below U.S. population norms (P < 0.001), whereas mental health scores were similar to population norms. Nineteen percent of the patients had symptoms of depression, 39% had symptoms of anxiety, and 8% had symptoms of posttraumatic stress disorder. Thirty-six percent were disabled, and 17% were working full-time. Early survivors of severe shock had a high 3-year survival rate. Patients' long-term physical and psychological outcomes were similar to those reported for cohorts of less severely ill intensive care unit survivors. Anxiety and depression were relatively common, but only a few patients had symptoms of posttraumatic stress disorder. This study supports the observation that acute illness severity does not determine long-term outcomes. Even extremely

Long-term variations of polar mesospheric summer echoes observed at Andøya (69°N)

NASA Astrophysics Data System (ADS)

Latteck, R.; Bremer, J.

2017-10-01

Polar mesosphere summer echoes (PMSE) are strong radar signals received at very high radar frequencies at altitudes between about 80 and 95 km at polar latitudes during summer. PMSE are caused by inhomogeneities in the electron density of the radar Bragg scale within the plasma of the cold summer mesopause region in the presence of negatively charged ice particles. Therefore, the occurrence of PMSE depends on the ionisation due to solar wave radiation and precipitating high energetic particle fluxes but also contains information about mesospheric temperature and water vapour content. Long-time observations of these echoes can be used to conclude on long-term changes of these atmospheric parameters. Continuous observations of PMSE have been carried out on the North-Norwegian island And/oya (69.3°N, 16.0°E) using the ALOMAR SOUSY radar (1994-1997), the ALWIN VHF radar (1999-2008) and the Middle Atmosphere Alomar Radar System MAARSY (since 2011). Since both the ALWIN radar and MAARSY are calibrated systems, the received echo strength of PMSE from 17 years of mesospheric observations (1999-2016) could be converted into absolute signal power. This data series could be extended to the years 1994 until 1997 on the basis of signal-to-noise ratio values derived during the years between 1994 and 2008. Seasonal mean values of PMSE occurrence for the time period from 1 June until 31 July have been derived and the resulting 23 years long data set was analyzed in dependence on solar and geomagnetic activity as well as analyzed for long-term trends. The PMSE occurrence rate is positively correlated with the solar Lyman α radiation (however low significance level) and the geomagnetic Ap index. After elimination of the solar and geomagnetically induced parts using different regression analysis methods, the PMSE data show a significant (χ = 92%-97%) positive trend during the observation period 1994 until 2016.

Atmospheric CO2 Variability Observed From ASCENDS Flight Campaigns

NASA Technical Reports Server (NTRS)

Lin, Bing; Browell, Edward; Campbell, Joel; Choi, Yonghoon; Dobler, Jeremy; Fan, Tai-Fang; Harrison, F. Wallace; Kooi, Susan; Liu, Zhaoyan; Meadows, Byron;

Pro-Am Collaboration for Support of NASA Comet ISON Observing Campaign (CIOC)

NASA Astrophysics Data System (ADS)

Yanamandra-Fisher, P. A.; Warner, E.

2013-09-01

From the initial discovery of C/2012 S1 (ISON) by Russian amateur astronomers in September 2012 [1] to the present day, amateur astronomers provide valuable resources of global coverage, data, and legacy knowledge to the professional community. The NASA Comet ISON Observing Campaign (CIOC) has leveraged professional-amateur collaborations via web and social media as part of its mission to facilitate a multi-spectral and multi-facility observation campaign that includes an armada of NASA's ground-based facilities, orbital observatories, and spacecraft. One of the most important goals of these pro-am collaborations is the monitoring of the morphological, photometric, and activity-related evolution of the comet.

Integrated Carbon Observation System (ICOS) - a domain-overarching long-term research infrastructure for the future

NASA Astrophysics Data System (ADS)

Lavric, J. V.; Juurola, E.; Vermeulen, A. T.; Kutsch, W. L.

2016-12-01

In a world that is undergoing climate change and is increasingly impacted by human influence, the need for globally integrated observations of greenhouse gases (GHG) and independent evaluation of their fluxes is becoming increasingly pressing. Since the 2015 COP21 meeting in Paris, such observation systems are also demanded by global stakeholders and policy makers. For successful monitoring and implementation of mitigation measures, the behavior of natural carbon pools must be well understood, the human carbon emission inventories better constrained, and the interaction between the two better studied. The Integrated Carbon Observation System (ICOS), currently comprising 12 member countries, is a European domain-overarching distributed research infrastructure dedicated to providing freely accessible long-term, high-quality data and data products on greenhouse gas (GHG) budgets and their evolution in terrestrial ecosystems, oceans and atmosphere. ICOS was built on the foundations of nationally-operated in-situ measurement facilities and modelling efforts. Today, it consists of National Networks, Central Facilities, and the European Research Infrastructure Consortium (ICOS ERIC), founded in November 2015. The long-term objective of ICOS is to remain independent, sustainable, on the forefront of scientific and technological development, and to find a good balance between scientific interests on one side and expectations of policy makers and society on the other. On the global scale, ICOS seeks to interlink with complementary research infrastructures (e.g. ACTRIS, IAGOS, etc.) to form partnerships that maximize the output and the effect of invested resources to the benefit of all stakeholders. A lot of attention will also be given to network design and attracting new partners from regions where such observations are still lacking in order to fill the gaps in the global observation network. In this presentation we present the latest developments concerning ICOS and its

Very long-term sequelae of craniopharyngioma.

PubMed

Wijnen, Mark; van den Heuvel-Eibrink, Marry M; Janssen, Joseph A M J L; Catsman-Berrevoets, Coriene E; Michiels, Erna M C; van Veelen-Vincent, Marie-Lise C; Dallenga, Alof H G; van den Berge, J Herbert; van Rij, Carolien M; van der Lely, Aart-Jan; Neggers, Sebastian J C M M

2017-06-01

Studies investigating long-term health conditions in patients with craniopharyngioma are limited by short follow-up durations and generally do not compare long-term health effects according to initial craniopharyngioma treatment approach. In addition, studies comparing long-term health conditions between patients with childhood- and adult-onset craniopharyngioma report conflicting results. The objective of this study was to analyse a full spectrum of long-term health effects in patients with craniopharyngioma according to initial treatment approach and age group at craniopharyngioma presentation. Cross-sectional study based on retrospective data. We studied a single-centre cohort of 128 patients with craniopharyngioma treated from 1980 onwards (63 patients with childhood-onset disease). Median follow-up since craniopharyngioma presentation was 13 years (interquartile range: 5-23 years). Initial craniopharyngioma treatment approaches included gross total resection ( n  = 25), subtotal resection without radiotherapy ( n  = 44), subtotal resection with radiotherapy ( n  = 25), cyst aspiration without radiotherapy ( n  = 8), and 90 Yttrium brachytherapy ( n  = 21). Pituitary hormone deficiencies (98%), visual disturbances (75%) and obesity (56%) were the most common long-term health conditions observed. Different initial craniopharyngioma treatment approaches resulted in similar long-term health effects. Patients with childhood-onset craniopharyngioma experienced significantly more growth hormone deficiency, diabetes insipidus, panhypopituitarism, morbid obesity, epilepsy and psychiatric conditions compared with patients with adult-onset disease. Recurrence-/progression-free survival was significantly lower after initial craniopharyngioma treatment with cyst aspiration compared with other therapeutic approaches. Survival was similar between patients with childhood- and adult-onset craniopharyngioma. Long-term health conditions were comparable after

Long-term neurological outcomes in West Nile virus-infected patients: an observational study.

PubMed

Weatherhead, Jill E; Miller, Vicki E; Garcia, Melissa N; Hasbun, Rodrigo; Salazar, Lucrecia; Dimachkie, Mazen M; Murray, Kristy O

2015-05-01

The Houston West Nile Cohort (HWNC) was founded in 2002 when West Nile virus (WNV) reached Houston, TX. The long-term outcomes following WNV infection are still mostly unknown, though neurological abnormalities up to 1 year postinfection have been documented. We report an observational study of neurological abnormalities at 1-3 and 8-11 years following WNV infection in the HWNC. We conducted standard neurological examinations at two separate time points to assess changes in neurological status over time. The majority of patients (86%, 30/35) with encephalitis had abnormal neurological exam findings at the time of the first assessment compared with uncomplicated fever (27%, 3/11) and meningitis (36%, 5/14) cases. At the time of the second assessment, 57% (4/7) of West Nile fever (WNF), 33% (2/6) of West Nile meningitis (WNM), and 36% (5/14) of West Nile encephalitis (WNE) had developed new neurological complications. The most common abnormalities noted were tandem gait, hearing loss, abnormal reflexes, and muscle weakness. Long-term neurological abnormalities were most commonly found in patients who experienced primary WNV encephalitis. New abnormalities may develop over time regardless of initial clinical infection. Future studies should aim to differentiate neurological consequences due to WNV neuroinvasive infection versus neurological decline related to comorbid conditions. © The American Society of Tropical Medicine and Hygiene.

Long-Term Observations of Ocean Biogeochemistry with Nitrate and Oxygen Sensors in Apex Profiling Floats

NASA Astrophysics Data System (ADS)

Johnson, K. S.; Coletti, L.; Jannasch, H.; Martz, T.; Swift, D.; Riser, S.

2008-12-01

Long-term, autonomous observations of ocean biogeochemical cycles are now feasible with chemical sensors in profiling floats. These sensors will enable decadal-scale observations of trends in global ocean biogeochemical cycles. Here, we focus on measurements on nitrate and dissolved oxygen. The ISUS (In Situ Ultraviolet Spectrophotometer) optical nitrate sensor has been adapted to operate in a Webb Research, Apex profiling float. The Apex float is of the type used in the Argo array and is designed for multi-year, expendable deployments in the ocean. Floats park at 1000 m depth and make 60 nitrate and oxygen measurements at depth intervals ranging from 50 m below 400 m to 5 m in the upper 100 m as they profile to the surface. All data are transmitted to shore using the Iridium telemetry system and they are available on the Internet in near-real time. Floats equipped with ISUS and an Aanderaa oxygen sensor are capable of making 280 vertical profiles from 1000 m. At a 5 day cycle time, the floats should have nearly a four year endurance. Three floats have now been deployed at the Hawaii Ocean Time series station (HOT), Ocean Station Papa (OSP) in the Gulf of Alaska and at 50 South, 30 East in the Southern Ocean. Two additional floats are designated for deployment at the Bermuda Atlantic Time Series station (BATS) and in the Drake Passage. The HOT float has made 56 profiles over 260 days and should continue operating for 3 more years. Nitrate concentrations are in excellent agreement with the long-term mean observed at HOT. No significant long-term drift in sensor response has occurred. A variety of features have been observed in the HOT nitrate data that are linked to contemporaneous changes in oxygen production and mesoscale dynamics. The impacts of these features will be briefly described. The Southern Ocean float has operated for 200 days and is now observing reinjection of nitrate into surface waters as winter mixing occurs(surface nitrate > 24 micromolar). We

Impact of the Tips From Former Smokers Campaign on Population-Level Smoking Cessation, 2012–2015

PubMed Central

Davis, Kevin C.; Beistle, Diane; King, Brian A.; Duke, Jennifer; Rodes, Robert; Graffunder, Corinne

2018-01-01

This study provides estimates of the long-term cumulative impact of the Centers for Disease Control and Prevention’s national tobacco education campaign, Tips From Former Smokers (Tips), on population-level smoking cessation. We used recently published estimates of the association between increased Tips campaign media doses and quit attempts to calculate campaign-attributable population sustained (6-month) quits during 2012–2015. Tips led to approximately 522,000 sustained quits during 2012–2015. These findings indicate that the Tips campaign’s comprehensive approach to combining evidence-based messages with the promotion of cessation resources was successful in achieving substantial long-term cigarette cessation at the population level over multiple years. PMID:29862960

Evaluating Clouds in Long-Term Cloud-Resolving Model Simulations with Observational Data

NASA Technical Reports Server (NTRS)

Zeng, Xiping; Tao, Wei-Kuo; Zhang, Minghua; Peters-Lidard, Christa; Lang, Stephen; Simpson, Joanne; Kumar, Sujay; Xie, Shaocheng; Eastman, Joseph L.; Shie, Chung-Lin;

The EuroSprite2005 Observational Campaign: an example of training and outreach opportunities for CAL young scientists

NASA Astrophysics Data System (ADS)

Chanrion, O.; Crosby, N. B.; Arnone, E.; Boberg, F.; van der Velde, O.; Odzimek, A.; Mika, Á.; Enell, C.-F.; Berg, P.; Ignaccolo, M.; Steiner, R. J.; Laursen, S.; Neubert, T.

2007-07-01

The four year "Coupling of Atmospheric Layers (CAL)" EU FP5 Research Training Network project studied unanswered questions related to transient luminous events (sprites, jets and elves) in the upper atmosphere. Consisting of ten scientific work-packages CAL also included intensive training and outreach programmes for the young scientists hired. Educational activities were based on the following elements: national PhD programmes, activities at CAL and other meetings, a dedicated summer school, and two European sprite observational campaigns. The young scientists were strongly involved in the latter and, as an example, the "EuroSprite2005" observational campaign is presented in detail. Some of the young scientists participated in the instrument set-up, others in the campaign logistics, some coordinated the observations, and others gathered the results to build a catalogue. During the four-month duration of this campaign, all of them took turns in operating the system and making their own night observations. The ongoing campaign activities were constantly advertised and communicated via an Internet blog. In summary the campaign required all the CAL young scientists to embark on experimental work, to develop their organisational skills, and to enhance their ability to communicate their activities. The campaign was a unique opportunity to train and strengthen skills that will be an asset to their future careers and, overall, was most successful.

LONG-TERM STABLE EQUILIBRIA FOR SYNCHRONOUS BINARY ASTEROIDS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jacobson, Seth A.; Scheeres, Daniel J.

Synchronous binary asteroids may exist in a long-term stable equilibrium, where the opposing torques from mutual body tides and the binary YORP (BYORP) effect cancel. Interior of this equilibrium, mutual body tides are stronger than the BYORP effect and the mutual orbit semimajor axis expands to the equilibrium; outside of the equilibrium, the BYORP effect dominates the evolution and the system semimajor axis will contract to the equilibrium. If the observed population of small (0.1-10 km diameter) synchronous binaries are in static configurations that are no longer evolving, then this would be confirmed by a null result in the observationalmore » tests for the BYORP effect. The confirmed existence of this equilibrium combined with a shape model of the secondary of the system enables the direct study of asteroid geophysics through the tidal theory. The observed synchronous asteroid population cannot exist in this equilibrium if described by the canonical 'monolithic' geophysical model. The 'rubble pile' geophysical model proposed by Goldreich and Sari is sufficient, however it predicts a tidal Love number directly proportional to the radius of the asteroid, while the best fit to the data predicts a tidal Love number inversely proportional to the radius. This deviation from the canonical and Goldreich and Sari models motivates future study of asteroid geophysics. Ongoing BYORP detection campaigns will determine whether these systems are in an equilibrium, and future determination of secondary shapes will allow direct determination of asteroid geophysical parameters.« less

Persistence of Change: Fume Hood Campaign Lessons

ERIC Educational Resources Information Center

Feder, Elah; Robinson, Jennifer; Wakefield, Sarah

2012-01-01

Purpose: Sustainability initiatives typically operate for a limited time period, but it is often unclear whether they have lasting effects. The purpose of this paper is to examine a laboratory fume hood campaign, in order to identify factors that might contribute or detract from long-term change persistence. Design/methodology/approach: The…

The 2011 Draconids: The First European Airborne Meteor Observation Campaign

NASA Astrophysics Data System (ADS)

Vaubaillon, Jeremie; Koten, Pavel; Margonis, Anastasios; Toth, Juraj; Rudawska, Regina; Gritsevich, Maria; Zender, Joe; McAuliffe, Jonathan; Pautet, Pierre-Dominique; Jenniskens, Peter; Koschny, Detlef; Colas, Francois; Bouley, Sylvain; Maquet, Lucie; Leroy, Arnaud; Lecacheux, Jean; Borovicka, Jiri; Watanabe, Junichi; Oberst, Jürgen

2015-02-01

On 8 October 2011, the Draconid meteor shower (IAU, DRA) was predicted to cause two brief outbursts of meteors, visible from locations in Europe. For the first time, a European airborne meteor observation campaign was organized, supported by ground-based observations. Two aircraft were deployed from Kiruna, Sweden, carrying six scientists, 19 cameras and eight crew members. The flight geometry was chosen such that it was possible to obtain double-station observations of many meteors. The instrument setup on the aircraft as well as on the ground is described in full detail. The main peak from 1900-dust ejecta happened at the predicted time and at the predicted rate. The second peak was observed from the earlier flight and from the ground, and was caused most likely by trails ejected in the nineteenth century. A total of 250 meteors were observed, for which light curve data were derived. The trajectory, velocity, deceleration and orbit of 35 double station meteors were measured. The magnitude distribution index was high, as a result of which there was no excess of meteors near the horizon. The light curve proved to be extremely flat on average, which was unexpected. Observations of spectra allowed us to derive the compositional information of the Draconids meteoroids and showed an early release of sodium, usually interpreted as resulting from fragile meteoroids. Lessons learned from this experience are derived for future airborne meteor shower observation campaigns.

Apical root resorption caused by orthodontic forces: A brief review and a long-term observation.

PubMed

Topkara, Ahu; Karaman, Ali I; Kau, Chung H

2012-10-01

External apical root resorption (ARR) is a common iatrogenic consequence of orthodontic treatment. One of the aims of this article is to present a brief overview of the literature, including; diagnosis and etiology, with emphasis on orthodontic forces to facilitate an understand of the prevention or management of ARR in orthodontic patients. We also present a long-term follow-up observation of severe ARR, including the last obtained cone beam computed tomography (CBCT) records, to demonstrate the effect of orthodontic forces on ARR.

Results from CoMStOC - The Coronal Magnetic Structures Observing Campaign

NASA Technical Reports Server (NTRS)

Schmelz, J. T.; Holman, G. D.

1991-01-01

The Coronal Magnetic Structures Observing Campaign (CoMStOC) was designed to measure the magnetic field strength and determine its structure in the solar corona. Simultaneous soft X-ray and microwave observations were taken by the Solar Maximum Mission's X-ray Polychromator (XRP) and the Very Large Array (VLA) on four days in the campaign period (Nov 25 to Dec 21, 1987). XRP maps in soft X-ray resonance lines formed at different coronal temperatures provide accurate temperature and emission measure diagnostics. VLA maps at several frequencies in the 20 cm and 6 cm bands yield information on microwave structure, spectrum and polarization. The combined data set separates contributions from the two dominant microwave emission mechanisms, thermal bremsstrahlung and gyroresonance. Where gyroresonance dominates, the coronal magnetic field strength has been determined with the aid of theoretical modeling.

Results from CoMStOC - The Coronal Magnetic Structures Observing Campaign

NASA Astrophysics Data System (ADS)

Schmelz, J. T.; Holman, G. D.

The Coronal Magnetic Structures Observing Campaign (CoMStOC) was designed to measure the magnetic field strength and determine its structure in the solar corona. Simultaneous soft X-ray and microwave observations were taken by the Solar Maximum Mission's X-ray Polychromator (XRP) and the Very Large Array (VLA) on four days in the campaign period (Nov 25 to Dec 21, 1987). XRP maps in soft X-ray resonance lines formed at different coronal temperatures provide accurate temperature and emission measure diagnostics. VLA maps at several frequencies in the 20 cm and 6 cm bands yield information on microwave structure, spectrum and polarization. The combined data set separates contributions from the two dominant microwave emission mechanisms, thermal bremsstrahlung and gyroresonance. Where gyroresonance dominates, the coronal magnetic field strength has been determined with the aid of theoretical modeling.

Dynamical model of long-term synaptic plasticity

PubMed Central

Abarbanel, Henry D. I.; Huerta, R.; Rabinovich, M. I.

2002-01-01

Long-term synaptic plasticity leading to enhancement in synaptic efficacy (long-term potentiation, LTP) or decrease in synaptic efficacy (long-term depression, LTD) is widely regarded as underlying learning and memory in nervous systems. LTP and LTD at excitatory neuronal synapses are observed to be induced by precise timing of pre- and postsynaptic events. Modification of synaptic transmission in long-term plasticity is a complex process involving many pathways; for example, it is also known that both forms of synaptic plasticity can be induced by various time courses of Ca2+ introduction into the postsynaptic cell. We present a phenomenological description of a two-component process for synaptic plasticity. Our dynamical model reproduces the spike time-dependent plasticity of excitatory synapses as a function of relative timing between pre- and postsynaptic events, as observed in recent experiments. The model accounts for LTP and LTD when the postsynaptic cell is voltage clamped and depolarized (LTP) or hyperpolarized (LTD) and no postsynaptic action potentials are evoked. We are also able to connect our model with the Bienenstock, Cooper, and Munro rule. We give model predictions for changes in synaptic strength when periodic spike trains of varying frequency and Poisson distributed spike trains with varying average frequency are presented pre- and postsynaptically. When the frequency of spike presentation exceeds ≈30–40 Hz, only LTP is induced. PMID:12114531

Long-term observation of aerosol cloud relationships in the Mid-Atlantic region

NASA Astrophysics Data System (ADS)

Li, S.; Joseph, E.; Min, Q.; Yin, B.

2013-12-01

Long-term ground-based observations of aerosol and cloud properties derived from measurements of Multifilter Rotating Shadow Band Radiometer and microwave radiometer at an atmospheric measurement field station in the Baltimore-Washington corridor operated by Howard University are used to examine the temporal variation of aerosol and cloud properties and moreover aerosol indirect effect on clouds. Through statistical analysis of five years (from 2006 to 2010) of these observations, the proportion of polluted cases is found larger in 2006 and 2007 and the proportion of optically thick clouds cases is also larger in 2006 and 2007 than that in 2008, 2009 and 2010. Both the mean aerosol optical depth (AOD) and cloud optical depth (COD) are observed decreasing from 2006 to 2010 but there is no obvious trend observed on cloud liquid water path (LWP). Because of the limit of AOD retrievals under cloudy conditions surface measurements of fine particle particulate matter 2.5 (PM2.5) were used for assessing aerosol indirect effect. A positive relationship between LWP and cloud droplets effective radius (Re) and a negative relationship between PM2.5 and Re are observed based on a stringent case selection method which is used to reduce the uncertainties from retrieval and meteorological impacts. The total 5 years summer time observations are segregated according to the value of PM2.5. Examination of distributions of COD, cloud condensation nuclei (CCN), cloud droplets effective radius and LWP under polluted and pristine conditions further confirm that the high aerosol loading decreases cloud droplets effective radius and increases cloud optical depth.

Long-term stream discharge and chemistry observations reveal unexpected ecosystem dynamics: Coweeta Watershed 7 clearcut manipulation

NASA Astrophysics Data System (ADS)

Jackson, C. R.; Webster, J. R.; Knoepp, J. D.; Elliott, K.; Emanuel, R. E.; Miniat, C.

2017-12-01

In the 1970s, the Coweeta Hydrologic Laboratory Watershed 7 was clearcut from ridge to ridge to observe how far the perturbation would move the ecosystem and how quickly the ecosystem would return to its pre-disturbance state. Nearly 40 years of observations of streamflow and DIN export demonstrate that this view of ecosystem resistance and resilience was too simplistic. Forest disturbance triggered a chain of ecological dynamics that are still evolving. For the first 12 years following watershed road building, forest harvest, and forest regeneration, streamflows and DIN concentrations temporarily increased and then appeared to return to pre-harvest behavior. Thereupon the ecosystem trajectory diverged from expectations. Unexpected successional changes in forest composition interacted with drought cycles, climate change effects, and forest changes due to pests and diseases to push the biogeochemical system into an alternate state featuring persistently high DIN concentrations and hydrological rather than biological control of DIN exports. Thirty years after harvest, these forest changes also increased evapotranspiration and reduced water yields. These ecosystem dynamics were only revealed because of long-term monitoring, and they inspired new research to elucidate mechanisms behind these dynamics. We conclude that long-term approaches are critical for understanding ecosystem dynamics and responses to disturbances.

Evaluating the effectiveness of an Australian obesity mass-media campaign: how did the 'Measure-Up' campaign measure up in New South Wales?

PubMed

King, E L; Grunseit, A C; O'Hara, B J; Bauman, A E

2013-12-01

In 2008, the Australian Government launched a mass-media campaign 'Measure-Up' to reduce lifestyle-related chronic disease risk. Innovative campaign messages linked waist circumference and chronic disease risk. Communication channels for the campaign included television, press, radio and outdoor advertising and local community activities. This analysis examines the impact of the campaign in the state of New South Wales, Australia. Cross-sectional telephone surveys (n = 1006 adults pre- and post-campaign) covered self-reported diet and physical activity, campaign awareness, knowledge about waist circumference, personal relevance of the message, perceived confidence to make lifestyle changes and waist-measuring behaviours. The campaign achieved high unprompted (38%) and prompted (89%) awareness. From pre- to post-campaign, knowledge and personal relevance of the link between waist circumference and chronic disease and waist measuring behaviour increased, although there were no significant changes in reported fruit and vegetable intake nor in physical activity. Knowledge of the correct waist measurement threshold for chronic disease risk increased over 5-fold, adjusted for demographic characteristics. 'Measure-Up' was successful at communicating the new campaign messages. Continued long-term investment in campaigns such as 'Measure-Up', supplemented with community-based health promotion, may contribute to population risk factor understanding and behaviour change to reduce chronic disease.

A Strategy to employ coordinated, autonomous Platforms for addressing long-term biochemical observing Tasks

NASA Astrophysics Data System (ADS)

Waldmann, H. C.; Montenegro, S.

2016-02-01

Autonomous platforms get a growing importance for ocean observing tasks in particular to enable long-term observing tasks. Employing the mobility of those platforms allows a targeted investigations of phenomena that up to now are mainly seen from satellite but are lacking detailed scrutiny. As part oft he national funded project ROBEX new operation concepts for mobile platforms are developed in particular a new type of underwater glider with larger payload capacity compared to legacy systems will be developed. First tests in the pool of a aparticular hull shape have led to a better understanding oft he hydrodynamic condition and an optomized hull design was derived from that. The WAVEGLIDER system of Liquid Robotics lends itsself to be used as a communication hub and a platform to track underwater vehicles. Therefore the combination of those systems are currently assessed in regard to a possible operation and its hard- and software implementation. A major issue ist o achieve a coordinated displacement of these completely decoupled systems. Issues on how to mitigate faulty mission runs, coping with low communication bandwidths, and ensuring adequate positioning information about the underwater glider have to be addressed. Robotic concepts known from terrestrial applications like for UAV systems are tested under the more stringent environmental conditions in ocean waters. With this combination of WAVEGLIDER and underwater glider it is planned to carry out long-term missions to investigate biochemical processes in the water column in particular to investigate the particle transport through the water column and the processes resulting from that. Concepts and first results of those tasks will be presented.

Dedicated Low Latitude Diurnal CO2 Frost Observation Campaigns by the Mars Climate Sounder

NASA Astrophysics Data System (ADS)

Piqueux, S.; Kass, D. M.; Kleinboehl, A.; Hayne, P. O.; Heavens, N. G.; McCleese, D. J.; Schofield, J. T.; Shirley, J. H.

2017-12-01

In December 2016 (Ls≈280, MY33) and July 2017 (Ls≈30, MY34), the Mars Climate Sounder (MCS) onboard the Mars Reconnaissance Orbiter (MRO) conducted two distinct observation campaigns. The first one aimed at 1) confirming the presence of low latitude diurnal CO2 frost on Mars, and 2) refining the estimated mass of carbon dioxide condensed at the surface, whereas the second campaign was designed to 3) search for temporally and spatially varying spectral characteristics indicative of frost properties (i.e., crystal size, contamination, etc.) and relationship to the regolith. To meet these goals, MCS acquired thermal infrared observations of the surface and atmosphere at variable local times (≈1.70-3.80 h Local True Solar Time) and in the 10°-50°N latitude band where very low thermal inertia material (<< 100 Jm-2K-1s-0.5) is present. Atmospherically corrected surface brightness temperatures were retrieved in a wavelength region around 32 μm (MCS channel B1) as well as at 12 μm, 16 μm and 22 μm (MCS channels A4, A1, A5) where possible. A preliminary analysis of the data suggests a good general agreement between these new observations and earlier predictions in terms of frost distribution and spectral properties. In addition, pre-frost deposition surface cooling rates are found to be consistent with those predicted by numerical models (i.e., 1-2K per hour). Finally, we observe buffered surface temperatures near the local frost point, indicating a surface emissivity ≈1. (i.e., optically thin frost layers, or dust contaminated frost, or slab-like ice) and no discernable frost metamorphism. We will present a detailed analysis of these new and unique observations, and elaborate on the potential relationship between the regolith and this recurring frost cycle.

Campaign datasets for ARM Cloud Aerosol Precipitation Experiment (ACAPEX)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leung, L. Ruby; Mei, Fan; Comstock, Jennifer

This campaign consisted of the deployment of the DOE ARM Mobile Facility 2 (AMF2) and the ARM Aerial Facility (AAF) G-1 in a field campaign called ARM Cloud Aerosol Precipitation Experiment (ACAPEX), which took place in conjunction with CalWater 2- a NOAA field campaign. The joint CalWater 2/ACAPEX field campaign aimed to improve understanding and modeling of large-scale dynamics and cloud and precipitation processes associated with ARs and aerosol-cloud interactions that influence precipitation variability and extremes in the western U.S. The observational strategy consisted of the use of land and offshore assets to monitor: 1. the evolution and structure ofmore » ARs from near their regions of development 2. the long-range transport of aerosols in the eastern North Pacific and potential interactions with ARs 3. how aerosols from long-range transport and local sources influence cloud and precipitation in the U.S. West Coast where ARs make landfall and post-frontal clouds are frequent.« less

Anomalous H-beta Variability in the 2014 NGC 5548 AGN-STORM Monitoring Campaign

NASA Astrophysics Data System (ADS)

Pei, Liuyi; AGN STORM Collaboration

2016-06-01

Reverberation mapping programs generally find that the continuum and H-beta flux variations in AGNs are well correlated. In the 2014 AGN STORM monitoring program for NGC 5548, we observed a distinct decorrelation of the emission-line light curves from the AGN continuum light curve during the second half of the six-month campaign. This effect was first detected for the C IV, Ly a, HeII 1640 and SiIV/OIV] 1400 lines in Hubble Space Telescope data, then observed for the H-beta line in ground-based data taken during the same monitoring period. We present measurements of the H-beta lags, equivalent width variations, and line responsivity changes during our campaign. We show that the AGN demonstrated unusual behavior in that the broad H-beta responsivity to flux variations decreased significantly during the second half of the campaign. The discovery of this decorrelation phenomenon was made possible by the high cadence and long duration of our monitoring campaign. More multi-wavelength observing campaigns with high sampling cadence, high signal-to-noise ratio, and long temporal baseline are needed for other AGNs in order to determine the prevalence of this phenomenon and to understand its physical origin.

Four multifaceted countrywide campaigns to promote hand hygiene in Belgian hospitals between 2005 and 2011: impact on compliance to hand hygiene.

PubMed

Costers, M; Viseur, N; Catry, B; Simon, A

2012-05-03

Four consecutive one-month campaigns were organised to promote hand hygiene in Belgian hospitals between 2005 and 2011. The campaigns included a combination of reminders in wards, educational sessions for healthcare workers, promotion of alcohol-based hand rub use, increasing patient awareness, and audits with performance feedback. Prior and after each one month intervention period, the infection control teams measured hand hygiene compliance of healthcare workers by direct observation using a standardised observation roster. A total of 738,367 opportunities for hand hygiene were observed over the four campaigns. Compliance with hand hygiene significantly increased from 49.6% before to 68.6% after the intervention period for the first, from 53.2% to 69.5% for the second, from 58.0% to 69.1% for the third, and from 62.3% to 72.9% for the fourth campaign. The highest compliance rates were consistently observed in paediatric units. Compliance rates were always markedly lower among physicians than nurses. After patient contact and body fluid exposure risk, compliance rates were noticeably higher than before patient contact and performing aseptic procedures. We conclude that repeated countrywide campaigns to promote hand hygiene result in positive long-term outcomes. However, lower compliance rates among physicians compared with nurses, before patient contact, and before performing aseptic procedures remain challenges for future campaigns.

Long-term potentiation and long-term depression: a clinical perspective

PubMed Central

Bliss, Timothy V.P.; Cooke, Sam F

2011-01-01

Long-term potentiation and long-term depression are enduring changes in synaptic strength, induced by specific patterns of synaptic activity, that have received much attention as cellular models of information storage in the central nervous system. Work in a number of brain regions, from the spinal cord to the cerebral cortex, and in many animal species, ranging from invertebrates to humans, has demonstrated a reliable capacity for chemical synapses to undergo lasting changes in efficacy in response to a variety of induction protocols. In addition to their physiological relevance, long-term potentiation and depression may have important clinical applications. A growing insight into the molecular mechanisms underlying these processes, and technological advances in non-invasive manipulation of brain activity, now puts us at the threshold of harnessing long-term potentiation and depression and other forms of synaptic, cellular and circuit plasticity to manipulate synaptic strength in the human nervous system. Drugs may be used to erase or treat pathological synaptic states and non-invasive stimulation devices may be used to artificially induce synaptic plasticity to ameliorate conditions arising from disrupted synaptic drive. These approaches hold promise for the treatment of a variety of neurological conditions, including neuropathic pain, epilepsy, depression, amblyopia, tinnitus and stroke. PMID:21779718

Arctic Observing Experiment (AOX) Field Campaign Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rigor, Ignatius; Johnson, Jim; Motz, Emily

Our ability to understand and predict weather and climate requires an accurate observing network. One of the pillars of this network is the observation of the fundamental meteorological parameters: temperature, air pressure, and wind. We plan to assess our ability to measure these parameters for the polar regions during the Arctic Observing Experiment (AOX, Figure 1) to support the International Arctic Buoy Programme (IABP), Arctic Observing Network (AON), International Program for Antarctic Buoys (IPAB), and Southern Ocean Observing System (SOOS). Accurate temperature measurements are also necessary to validate and improve satellite measurements of surface temperature across the Arctic. Support formore » research associated with the campaign is provided by the National Science Foundation, and by other US agencies contributing to the US Interagency Arctic Buoy Program. In addition to the support provided by the U.S Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Climate Research Facility’s North Slope of Alaska (NSA) site at Barrow and the National Science Foundation (NSF), the U.S. IABP is supported by the U.S. Coast Guard (USCG), the National Aeronautics and Space Administration (NASA), the National Ice Center (NIC), the National Oceanic and Atmospheric Administration (NOAA), and the Office of Naval Research (ONR).« less

Long-Term Trends Worldwide in Ambient NO2 Concentrations Inferred from Satellite Observations.

PubMed

Geddes, Jeffrey A; Martin, Randall V; Boys, Brian L; van Donkelaar, Aaron

2016-03-01

Air pollution is associated with morbidity and premature mortality. Satellite remote sensing provides globally consistent decadal-scale observations of ambient nitrogen dioxide (NO2) pollution. We determined global population-weighted annual mean NO2 concentrations from 1996 through 2012. We used observations of NO2 tropospheric column densities from three satellite instruments in combination with chemical transport modeling to produce a global 17-year record of ground-level NO2 at 0.1° × 0.1° resolution. We calculated linear trends in population-weighted annual mean NO2 (PWMNO2) concentrations in different regions around the world. We found that PWMNO2 in high-income North America (Canada and the United States) decreased more steeply than in any other region, having declined at a rate of -4.7%/year [95% confidence interval (CI): -5.3, -4.1]. PWMNO2 decreased in western Europe at a rate of -2.5%/year (95% CI: -3.0, -2.1). The highest PWMNO2 occurred in high-income Asia Pacific (predominantly Japan and South Korea) in 1996, with a subsequent decrease of -2.1%/year (95% CI: -2.7, -1.5). In contrast, PWMNO2 almost tripled in East Asia (China, North Korea, and Taiwan) at a rate of 6.7%/year (95% CI: 6.0, 7.3). The satellite-derived estimates of trends in ground-level NO2 were consistent with regional trends inferred from data obtained from ground-station monitoring networks in North America (within 0.7%/year) and Europe (within 0.3%/year). Our rankings of regional average NO2 and long-term trends differed from the satellite-derived estimates of fine particulate matter reported elsewhere, demonstrating the utility of both indicators to describe changing pollutant mixtures. Long-term trends in satellite-derived ambient NO2 provide new information about changing global exposure to ambient air pollution. Our estimates are publicly available at http://fizz.phys.dal.ca/~atmos/martin/?page_id=232.

Short- and Long-Term Propagation of Spacecraft Orbits

NASA Technical Reports Server (NTRS)

Smith, John C., Jr.; Sweetser, Theodore; Chung, Min-Kun; Yen, Chen-Wan L.; Roncoli, Ralph B.; Kwok, Johnny H.; Vincent, Mark A.

2008-01-01

The Planetary Observer Planning Software (POPS) comprises four computer programs for use in designing orbits of spacecraft about planets. These programs are the Planetary Observer High Precision Orbit Propagator (POHOP), the Planetary Observer Long-Term Orbit Predictor (POLOP), the Planetary Observer Post Processor (POPP), and the Planetary Observer Plotting (POPLOT) program. POHOP and POLOP integrate the equations of motion to propagate an initial set of classical orbit elements to a future epoch. POHOP models shortterm (one revolution) orbital motion; POLOP averages out the short-term behavior but requires far less processing time than do older programs that perform long-term orbit propagations. POPP postprocesses the spacecraft ephemeris created by POHOP or POLOP (or optionally can use a less accurate internal ephemeris) to search for trajectory-related geometric events including, for example, rising or setting of a spacecraft as observed from a ground site. For each such event, POPP puts out such user-specified data as the time, elevation, and azimuth. POPLOT is a graphics program that plots data generated by POPP. POPLOT can plot orbit ground tracks on a world map and can produce a variety of summaries and generic ordinate-vs.-abscissa plots of any POPP data.

A report from YMC Sumatra field campaign

NASA Astrophysics Data System (ADS)

Yoneyama, K.; Yokoi, S.; Mori, S.; Nasuno, T.; Yamanaka, M. D.; Yasunaga, K.; Haryoko, U.; Nurhayati, N.; Syamsudin, F.

2017-12-01

Years of the Maritime Continent (YMC) is a two-year international field campaign from July 2017 through the early 2020. It aims at enhancing our knowledge of weather-climate systems over the Maritime Continent and its relation to higher latitudes through observations and numerical modeling. YMC field observations consist of several Intensive Observation Periods (IOPs) and routine basis long-term observations done by local agencies. One of IOPs is a joint effort done by Japanese and Indonesian research groups and we call it YMC-Sumatra, which studies precipitation mechanism along the west coast of Sumatra Island (Bengkulu city) especially focusing on a relationship between diurnal cycle convection and large-scale disturbances such as the Madden-Julian Oscillation (MJO). Observations will be carried out from November 16, 2017 through January 15, 2018. Since it is known that diurnally developed convection over the coast propagates offshore in the night time, we will deploy a ship off the coast in addition to the land-based site in Bengkulu meteorological station. From both sides, we conduct scanning weather radars, 3-hourly radiosonde soundings, and continuous surface meteorological measurements. Ocean surface is also intensively measured by 3-hourly CTD, ADCP, turbulent sensor, and so on from the ship. In addition, two types of forecast run (global 7-/14-km mesh for 14-/30-day forecast) using NICAM will be performed. Since this campaign in Sumatra is being done during the AGU meeting, a preliminary live report will be provided, so that scientific results as well as logistics information can be used for further IOPs.

Real-Time Observation of Apathy in Long-Term Care Residents With Dementia: Reliability of the Person-Environment Apathy Rating Scale.

PubMed

Jao, Ying-Ling; Mogle, Jacqueline; Williams, Kristine; McDermott, Caroline; Behrens, Liza

2018-04-01

Apathy is prevalent in individuals with dementia. Lack of responsiveness to environmental stimulation is a key characteristic of apathy. The Person-Environment Apathy Rating (PEAR) scale consists of environment and apathy subscales, which allow for examination of environmental impact on apathy. The interrater reliability of the PEAR scale was examined via real-time observation. The current study included 45 observations of 15 long-term care residents with dementia. Each participant was observed at three time points for 10 minutes each. Two raters observed the participant and surrounding environment and independently rated the participant's apathy and environmental stimulation using the PEAR scale. Weighted Kappa was 0.5 to 0.82 for the PEAR-Environment subscale and 0.5 to 0.8 for the PEAR-Apathy subscale. Overall, with the exception of three items with relatively weak reliability (0.50 to 0.56), the PEAR scale showed moderate to strong interrater reliability (0.63 to 0.82). The results support the use of the PEAR scale to measure environmental stimulation and apathy via real-time observation in long-term care residents with dementia. [Journal of Gerontological Nursing, 44(4), 23-28.]. Copyright 2018, SLACK Incorporated.

Evaluation of the association between long-lasting insecticidal nets mass distribution campaigns and child malaria in Nigeria.

PubMed

Kyu, Hmwe Hmwe; Georgiades, Katholiki; Shannon, Harry S; Boyle, Michael H

2013-01-09

Nigeria carries the greatest malaria burden among countries in the world. As part of the National Malaria Control Strategic Plan, free long-lasting insecticidal nets (LLINs) were distributed in 14 states of Nigeria through mass campaigns led by different organizations (the World Bank, UNICEF, or the Global Fund) between May 2009 and August 2010. The objective of this study was to evaluate the association between LLIN distribution campaigns and child malaria in Nigeria. Data were from the Nigeria Malaria Indicator Survey which was carried out from October to December 2010 on a nationally representative sample of households. Participants were women aged 15-49 years and their children aged less than five years (N = 4082). The main outcome measure was the presence or absence of malaria parasites in blood samples of children (6-59 months). Compared with children living in communities with no campaigns, those in the campaign areas were less likely to test positive for malaria after adjusting for geographic locations, community- and individual-level characteristics including child-level use of insecticide-treated nets (ITNs). The protective effects were statistically significant for the World Bank Booster Project areas (OR = 0.18, 95% CI = 0.04-0.73) but did not reach statistical significance for other campaign areas. Results also showed that community-level wealth (OR = 0.51, 95% CI = 0.34-0.76), community-level maternal knowledge regarding malaria prevention (OR = 0.70, 95% CI = 0.50-0.97), and child-level use of ITNs (OR = 0.79, 95% CI = 0.63-0.99) were negatively associated with child malaria. The observed protective effects on child malaria of these campaigns (statistically significant in the World Bank Booster Project areas and non-significant in the other areas) need to be corroborated by future effectiveness studies. Results also show that improving community-level maternal knowledge through appropriate channels might be helpful

Short-Term Impact of a Multimedia Communication Campaign on Children's Physical Activity Beliefs and Behavior.

PubMed

Bélanger-Gravel, Ariane; Cutumisu, Nicoleta; Lagarde, François; Laferté, Marilie; Gauvin, Lise

2017-01-01

To examine the short-term impact of the WIXX multimedia communication campaign on children's physical activity (PA) beliefs and behaviors, 3 repeated cross-sectional telephone surveys were conducted before, 9 months after, and 21 months after the launch of the campaign. A random-digit dialing procedure was used to recruit children ages 9 to 13 years. Children's PA beliefs, behaviors, and recall of the WIXX ads were self-reported. Logistic regression models showed that girls exposed to the WIXX ads were more likely to believe that PA would help to make new friends (odds ratio [OR] = 1.4, 95% confidence interval [CI] [1.0, 1.9]) and that they can be active even if too busy (OR = 1.4, 95% CI [1.0, 1.8]) compared to girls not exposed. Boys exposed were more likely to believe that PA would help to spend time with friends (OR = 1.4, 95% CI [1.1, 1.9]). Boys (OR = 1.5, 95% CI [1.1, 2.0.]) and girls (OR = 1.4, 95% CI [1.1, 1.8]) exposed were more likely to report having tried new PAs. No significant impact of the campaign was observed on overall PA after we controlled for confounders. Recall of the WIXX ads was associated with a significant, albeit modest, impact on some PA beliefs and intermediate PA behaviors.

Results from the JPL IGS Analysis Center IGS14 Reprocessing Campaign

NASA Astrophysics Data System (ADS)

Ries, P. A.; Amiri, N.; Heflin, M. B.; Sakumura, C.; Sibois, A. E.; Sibthorpe, A.; David, M. W.

2017-12-01

The JPL IGS analysis center has begun a campaign to reprocess GPS orbits and clocks in the IGS14 reference frame. Though the new frame is only a few millimeters offset from the previous IGb08 frame, a reprocessing is required for consistent use of the new frame due to a change in the satellite phase center offsets between the frames. We will present results on the reprocessing campaign from 2002 to present in order to evaluate any effects caused by the new frame. We also create long-term time-series and periodograms of translation, rotation, and scale parameters to see if there is any divergence between the frames. We will also process long-term PPP time series and derived velocities for a well-distributed set of stations in each frame to compare with the published frame offsets.

Congenital diaphragmatic hernia: Observed/expected lung-to-head ratio as a predictor of long-term morbidity.

PubMed

King, Sebastian K; Alfaraj, Malikah; Gaiteiro, Rose; O'Brien, Karel; Moraes, Theo; Humpl, Tilman; Marcon, Margaret; Chiang, Monping; Reyes, Janette; Haliburton, Beth; Ryan, Greg; Cox, Peter; Chiu, Priscilla P L

2016-05-01

The aim of this study was to investigate the association of observed/expected (O/E) lung-to-head ratio (LHR) with long-term morbidity for isolated fetal congenital diaphragmatic hernia (CDH) patients in a single institution. We performed a retrospective study of prenatally diagnosed CDH from 18 to 38weeks of gestation (01/2002-04/2010). Two cohorts of O/E LHR were defined (22.6-45%, 45.1-78.3%) based upon previous studies. Survivors with at least 1-year follow-up of prospectively collected long-term morbidity assessments were included. O/E LHR was available in 43 survivors (median 40%, range 22.8-78.3%). Follow-up data were available in 41 survivors (M:F=24:17, left CDH=39/41). Median follow-up was 6.5years (1-11years). Height/weight trajectories were similar between the two cohorts, with the majority below the 50th centile. There were no differences between the two cohorts by age 3years for Bayley scales (developmental domains) and/or REEL-3 (language development). In addition, V/Q scans in the two cohorts demonstrated similar degrees of mismatch (mean delta V/Q=35.4 versus 31.3). In fetuses with isolated CDH, a reduction in O/E LHR does not predict a worse outcome in long-term follow-up. There is no association between a lower O/E LHR and a reduction in REEL-3 or Bayley score nor V/Q mismatch. Copyright © 2016 Elsevier Inc. All rights reserved.

Observer-rated depression in long-term care: frequency and risk factors.

PubMed

McCusker, Jane; Cole, Martin G; Voyer, Philippe; Monette, Johanne; Champoux, Nathalie; Ciampi, Antonio; Vu, Minh; Dyachenko, Alina; Belzile, Eric

2014-01-01

The objectives of this study were: (1) to describe the prevalence and 6-month incidence of observer-rated depression in residents age 65 and over of long-term care (LTC) facilities; (2) to describe risk factors for depression, at baseline and over time. A multisite, prospective observational study was conducted in residents aged 65 and over of 7 LTC facilities. The Cornell Scale for Depression in Dementia (CSDD) was completed by nurses monthly for 6 months. We measured demographic, medical, and functional factors at baseline and monthly intervals, using data from research assessments, nurse interviews, and chart reviews. 274 residents were recruited and completed baseline depression assessments. The prevalence of depression (CSDD score of 6+) was 19.0%. The incidence of depression among those without prevalent depression was 73.3 per 100 person-years. A delirium diagnosis, pain, and diabetes were independently associated with prevalent depression. CSDD score at baseline and development of severe cognitive impairment at follow-up were independent risk factors for incident depression. A diagnosis of delirium and uncorrected visual impairment at follow-up occurred concurrently with incident depression. The results of this study have implications for the detection and prevention of depression in LTC. Delirium diagnosis, pain and diabetes at baseline were associated with prevalent depression; depression symptoms at baseline and development of severe cognitive impairment at follow-up were risk factors for incident depression. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Long-term observations of Boreal Toads at an ARMI apex site

USGS Publications Warehouse

Corn, Paul Stephen; Muths, Erin L.; Pilliod, David S.

2011-01-01

The U.S. Geological Survey’s Amphibian Research and Monitoring Initiative (ARMI) is a national project with goals to monitor the status and trends of amphibians, conduct research on causes of declines, and provide information and support to management agencies for conservation of amphibian populations. ARMI activities are organized around extensive inventories and place-based monitoring (such as collaboration with the Greater Yellowstone Inventory and Monitoring Network), and intensive population studies and research at selected locations (apex sites). One such site is an oxbow pond on the Buffalo Fork near the Black Rock Ranger Station east of Grand Teton National Park. We have been conducting mark-recapture of boreal toads (Anaxyrus boreas) at Black Rock since 2002. In concert with studies of other toad populations in the Rocky Mountains, we have documented a high rate of incidence of the chytrid fungus Batrachochytrium dendrobatidis (Bd) and a negative rate of growth of the toad population, but not the population crash or extinction observed in other populations with high prevalence of Bd. Long-term observations at other ARMI apex sites have proven invaluable for studying effects of climate change on amphibian behavior, and the Black Rock site has been upgraded with onsite recording of weather data and auditory monitoring of other amphibian species. Continued research at Black Rock will be critical for understanding the interrelated effects of climate and disease on amphibians in the Greater Yellowstone Ecosystem.

Synaptic Transmission Optimization Predicts Expression Loci of Long-Term Plasticity.

PubMed

Costa, Rui Ponte; Padamsey, Zahid; D'Amour, James A; Emptage, Nigel J; Froemke, Robert C; Vogels, Tim P

2017-09-27

Long-term modifications of neuronal connections are critical for reliable memory storage in the brain. However, their locus of expression-pre- or postsynaptic-is highly variable. Here we introduce a theoretical framework in which long-term plasticity performs an optimization of the postsynaptic response statistics toward a given mean with minimal variance. Consequently, the state of the synapse at the time of plasticity induction determines the ratio of pre- and postsynaptic modifications. Our theory explains the experimentally observed expression loci of the hippocampal and neocortical synaptic potentiation studies we examined. Moreover, the theory predicts presynaptic expression of long-term depression, consistent with experimental observations. At inhibitory synapses, the theory suggests a statistically efficient excitatory-inhibitory balance in which changes in inhibitory postsynaptic response statistics specifically target the mean excitation. Our results provide a unifying theory for understanding the expression mechanisms and functions of long-term synaptic transmission plasticity. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Long-term ecological research in a human-dominated world

Treesearch

G. Philip Robertson; Scott L. Collins; David R. Foster; Nicholas Brokaw; Hugh W. Ducklow; Ted L. Gragson; Corinna Gries; Stephen K. Hamilton; A. David McGuire; John C. Moore; Emily H. Stanley; Robert B. Waide; Mark W. Williams

2012-01-01

The US Long Term Ecological Research (LTER) Network enters its fourth decade with a distinguished record of achievement in ecological science. The value of long-term observations and experiments has never been more important for testing ecological theory and for addressing today’s most difficult environmental challenges. The network’s potential for tackling emergent...

Long Term Monitoring of the Io Plasma Torus During the Galileo Encounter

NASA Technical Reports Server (NTRS)

Brown, Michael E.

2002-01-01

In the fall of 1999, the Galileo spacecraft made four passes into the Io plasma torus, obtaining the best in situ measurements ever of the particle and field environment in this densest region of the Jovian magnetosphere. Supporting observations from the ground are vital for understanding the global and temporal context of the in situ observations. We conducted a three-month-long Io plasma torus monitoring campaign centered on the time of the Galileo plasma torus passes to support this aspect of the Galileo mission. The almost-daily plasma density and temperature measurements obtained from our campaign allow the much more sparse but also much more detailed Galileo data to be used to address the issues of the structure of the Io plasma torus, the stability mechanism of the Jovian magnetosphere, the transport of material from the source region near Io, and the nature and source of persistent longitudinal variations. Combining the ground-based monitoring data with the detailed in situ data offers the only possibility for answering some of the most fundamental questions about the nature of the Io plasma torus.

Glacier foreland colonisation: distinguishing between short-term and long-term effects of climate change.

PubMed

Kaufmann, Rüdiger

2002-02-01

By comparing short-term (6 years) observations with long-term (>100 years) community changes reconstructed from the chronosequence along a glacier foreland, I show that the colonisation of recently deglaciated terrain by invertebrates may constitute a process reacting sensitively to temperature fluctuations. Early colonising stages (<30 years old) currently develop faster, and intermediate successional stages (30-50 years old) slower, than would be indicated by the long-term chronosequence pattern. These differences between the chronosequence approach and direct observation can be explained by a simple model relating the rate of community evolution to the temperature record. It would mean that an increase of 0.6°C in summer temperatures approximately doubled the speed of initial colonisation, whereas later successional stages were less sensitive to climate change. The present situation appears to result from unusually warm summers around 1950 and a warm period accelerating glacier retreat since 1980. In contrast to the long-term trend, all except the youngest communities have suffered a loss in diversity in recent years.

Short-Term Plasticity and Long-Term Potentiation in Magnetic Tunnel Junctions: Towards Volatile Synapses

NASA Astrophysics Data System (ADS)

Sengupta, Abhronil; Roy, Kaushik

2016-02-01

Synaptic memory is considered to be the main element responsible for learning and cognition in humans. Although traditionally nonvolatile long-term plasticity changes are implemented in nanoelectronic synapses for neuromorphic applications, recent studies in neuroscience reveal that biological synapses undergo metastable volatile strengthening followed by a long-term strengthening provided that the frequency of the input stimulus is sufficiently high. Such "memory strengthening" and "memory decay" functionalities can potentially lead to adaptive neuromorphic architectures. In this paper, we demonstrate the close resemblance of the magnetization dynamics of a magnetic tunnel junction (MTJ) to short-term plasticity and long-term potentiation observed in biological synapses. We illustrate that, in addition to the magnitude and duration of the input stimulus, the frequency of the stimulus plays a critical role in determining long-term potentiation of the MTJ. Such MTJ synaptic memory arrays can be utilized to create compact, ultrafast, and low-power intelligent neural systems.

Preparedness of elderly long-term care facilities in HSE East for influenza outbreaks.

PubMed

O'Connor, L; Boland, M; Murphy, H

2015-01-01

Abstract We assessed preparedness of HSE East elderly long-term care facilities for an influenza outbreak, and identified Public Health Department support needs. We surveyed 166 facilities based on the HSE checklist document for influenza outbreaks, with 58% response rate. Client flu vaccination rates were > 75%; leading barriers were client anxiety and consent issues. Target flu vaccine uptake of 40% in staff occurred in 43% of facilities and was associated with staff vaccine administration by afacility-attached GP (p = 0.035), having a facility outbreak plan (p = 0.013) and being anon-HSE run facility (p = 0.013). Leading barriers were staff personal anxiety (94%) and lack of awareness of the protective effect on clients (21%). Eighty-nine percent found Public Health helpful, and requested further educational support and advocacy. Staff vaccine uptake focus, organisational leadership, optimal vaccine provision models, outbreak plans and Public Health support are central to the influenza campaign in elderly long-term care facilities.

Very-long-term and short-term chromatic adaptation: are their influences cumulative?

PubMed

Belmore, Suzanne C; Shevell, Steven K

2011-02-09

Very-long-term (VLT) chromatic adaptation results from exposure to an altered chromatic environment for days or weeks. Color shifts from VLT adaptation are observed hours or days after leaving the altered environment. Short-term chromatic adaptation, on the other hand, results from exposure for a few minutes or less, with color shifts measured within seconds or a few minutes after the adapting light is extinguished; recovery to the pre-adapted state is complete in less than an hour. Here, both types of adaptation were combined. All adaptation was to reddish-appearing long-wavelength light. Shifts in unique yellow were measured following adaptation. Previous studies demonstrate shifts in unique yellow due to VLT chromatic adaptation, but shifts from short-term chromatic adaptation to comparable adapting light can be far greater than from VLT adaptation. The question considered here is whether the color shifts from VLT adaptation are cumulative with large shifts from short-term adaptation or, alternatively, does simultaneous short-term adaptation eliminate color shifts caused by VLT adaptation. The results show the color shifts from VLT and short-term adaptation together are cumulative, which indicates that both short-term and very-long-term chromatic adaptation affect color perception during natural viewing. Copyright © 2010 Elsevier Ltd. All rights reserved.

A Reevaluation of Airborne HO(x) Observations from NASA Field Campaigns

NASA Technical Reports Server (NTRS)

Olson, Jennifer; Crawford, James H.; Chen, Gao; Brune, William H.; Faloona, Ian C.; Tan, David; Harder, Hartwig; Martinez, Monica

2006-01-01

In-situ observations of tropospheric HO(x) (OH and HO2) obtained during four NASA airborne campaigns (SUCCESS, SONEX, PEM-Tropics B and TRACE-P) are reevaluated using the NASA Langley time-dependent photochemical box model. Special attention is given to previously diagnosed discrepancies between observed and predicted HO2 which increase with higher NO(x) levels and at high solar zenith angles. This analysis shows that much of the model discrepancy at high NO(x) during SUCCESS can be attributed to modeling observations at time-scales too long to capture the nonlinearity of HO(x) chemistry under highly variable conditions for NO(x). Discrepancies at high NO(x) during SONEX can be moderated to a large extent by complete use of all available precursor observations. Differences in kinetic rate coefficients and photolysis frequencies available for previous studies versus current recommendations also explain some of the disparity. Each of these causes is shown to exert greater influence with increasing NO(x) due to both the chemical nonlinearity between HO(x) and NO(x) and the increased sensitivity of HO(x) to changes in sources at high NO(x). In contrast, discrepancies at high solar zenith angles will persist until an adequate nighttime source of HO(x) can be identified. It is important to note that this analysis falls short of fully eliminating the issue of discrepancies between observed and predicted HO(x) for high NO(x) environments. These discrepancies are not resolved with the above causes in other data sets from ground-based field studies. Nevertheless, these results highlight important considerations in the application of box models to observationally based predictions of HO(x) radicals.

Magnetic Field Observations at Purcell, Oklahoma Field Campaign Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chi, P. J.; Gibson, J. P.

The campaign “Magnetic Field Observations at Purcell, Oklahoma” installed a ground-based magnetometer at Purcell’s U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Climate Research Facility boundary installation at the Kessler Atmospheric and Ecological Field Station, University of Oklahoma, to measure local magnetic field variations. It is a part of the nine stations of the Mid-continent MAgnetoseismic Chain (McMAC) placed as close to the 330° magnetic longitude as possible. This is the meridian in the world where land covers the greatest continuous range in magnetic latitude. Figure 1 shows the map of the magnetometer stations along the 330th magnetic meridian,more » including the Purcell (PCEL) station. The main scientific objective of the campaign is to detect the field line resonance (FLR) frequencies of the magnetic field line connected to the Purcell station. This magnetic field line extends from Purcell to the outer space at distances as far as 2 Earth radii (RE). To accurately identify FLR frequencies, however, simultaneous measurements at slightly different latitudes along the same meridian are necessary to allow the use of the cross-phase technique. This consideration explains the arrangement to operate magnetometers at the Americus (AMER) and Richardson (RICH) stations nearby. The measured resonant frequency can infer the plasma mass density along the field line through the method of normal-mode magnetoseismology. The magnetometer at the Purcell station can detect many other types of magnetic field fluctuations associated with the changes in the electric currents in the ionosphere and the magnetosphere, which by large are affected by the solar activity. In other words, the magnetic field data collected by this campaign are also useful for understanding space weather phenomena. The magnetometer was installed at Purcell’s ARM boundary facility in March 27, 2006. The construction of the triaxial fluxgate magnetometer used

Long-term course of opioid addiction.

PubMed

Hser, Yih-Ing; Evans, Elizabeth; Grella, Christine; Ling, Walter; Anglin, Douglas

2015-01-01

Opioid addiction is associated with excess mortality, morbidities, and other adverse conditions. Guided by a life-course framework, we review the literature on the long-term course of opioid addiction in terms of use trajectories, transitions, and turning points, as well as other factors that facilitate recovery from addiction. Most long-term follow-up studies are based on heroin addicts recruited from treatment settings (mostly methadone maintenance treatment), many of whom are referred by the criminal justice system. Cumulative evidence indicates that opioid addiction is a chronic disorder with frequent relapses. Longer treatment retention is associated with a greater likelihood of abstinence, whereas incarceration is negatively related to subsequent abstinence. Over the long term, the mortality rate of opioid addicts (overdose being the most common cause) is about 6 to 20 times greater than that of the general population; among those who remain alive, the prevalence of stable abstinence from opioid use is low (less than 30% after 10-30 years of observation), and many continue to use alcohol and other drugs after ceasing to use opioids. Histories of sexual or physical abuse and comorbid mental disorders are associated with the persistence of opioid use, whereas family and social support, as well as employment, facilitates recovery. Maintaining opioid abstinence for at least five years substantially increases the likelihood of future stable abstinence. Recent advances in pharmacological treatment options (buprenorphine and naltrexone) include depot formulations offering longer duration of medication; their impact on the long-term course of opioid addiction remains to be assessed.

The 2006-2007 Observing Campaign On VX Hydrae

NASA Astrophysics Data System (ADS)

Templeton, Matthew R.; Samolyk, G.; Dvorak, S.; Poklar, R.; Butterworth, N.; Gerner, H. S.

2009-12-01

We present the results of the 2006-2007 observing campaign on the double-mode delta Scuti star VX Hydrae. Nearly 8800 V-band CCD observations were obtained during the two observing seasons. Although the data were taken with small telescopes (0.3-m or less, using consumer-grade CCD cameras), the data quality is very high, enabling the detection of variability at the millimagnitude level at some frequencies. Analysis of the data yields only two primary pulsation frequencies: f(0) = 4.4765 c/d, and f(1) = 5.7899 c/d. The two modes have comparable amplitude, although the amplitude of f(1) appears to have increased slightly from 2006 to 2007 by 0.01 mag. Only two pulsation modes are detected, but at least 18 additional linear combination frequencies are also clearly detected, some having amplitudes as low as 1 mmag, resulting in an incredibly rich Fourier spectrum. We discuss the evidence for amplitude variation in VX Hydrae, along with prospects for future study of this and other similar delta Scuti stars by AAVSO observers.

Capturing the sensitivity of land-use regression models to short-term mobile monitoring campaigns using air pollution micro-sensors.

PubMed

Minet, L; Gehr, R; Hatzopoulou, M

2017-11-01

The development of reliable measures of exposure to traffic-related air pollution is crucial for the evaluation of the health effects of transportation. Land-use regression (LUR) techniques have been widely used for the development of exposure surfaces, however these surfaces are often highly sensitive to the data collected. With the rise of inexpensive air pollution sensors paired with GPS devices, we witness the emergence of mobile data collection protocols. For the same urban area, can we achieve a 'universal' model irrespective of the number of locations and sampling visits? Can we trade the temporal representation of fixed-point sampling for a larger spatial extent afforded by mobile monitoring? This study highlights the challenges of short-term mobile sampling campaigns in terms of the resulting exposure surfaces. A mobile monitoring campaign was conducted in 2015 in Montreal; nitrogen dioxide (NO 2 ) levels at 1395 road segments were measured under repeated visits. We developed LUR models based on sub-segments, categorized in terms of the number of visits per road segment. We observe that LUR models were highly sensitive to the number of road segments and to the number of visits per road segment. The associated exposure surfaces were also highly dissimilar. Copyright © 2017 Elsevier Ltd. All rights reserved.

Inflammatory markers in relation to long-term air pollution.

PubMed

Mostafavi, Nahid; Vlaanderen, Jelle; Chadeau-Hyam, Marc; Beelen, Rob; Modig, Lars; Palli, Domenico; Bergdahl, Ingvar A; Vineis, Paolo; Hoek, Gerard; Kyrtopoulos, Soterios Α; Vermeulen, Roel

2015-08-01

Long-term exposure to ambient air pollution can lead to chronic health effects such as cancer, cardiovascular and respiratory disease. Systemic inflammation has been hypothesized as a putative biological mechanism contributing to these adverse health effects. We evaluated the effect of long-term exposure to air pollution on blood markers of systemic inflammation. We measured a panel of 28 inflammatory markers in peripheral blood samples from 587 individuals that were biobanked as part of a prospective study. Participants were from Varese and Turin (Italy) and Umea (Sweden). Long-term air pollution estimates of nitrogen oxides (NOx) were available from the European Study of Cohorts for Air Pollution Effects (ESCAPE). Linear mixed models adjusted for potential confounders were applied to assess the association between NOx and the markers of inflammation. Long-term exposure to NOx was associated with decreased levels of interleukin (IL)-2, IL-8, IL-10 and tumor necrosis factor-α in Italy, but not in Sweden. NOx exposure levels were considerably lower in Sweden than in Italy (Sweden: median (5th, 95th percentiles) 6.65 μg/m(3) (4.8, 19.7); Italy: median (5th, 95th percentiles) 94.2 μg/m(3) (7.8, 124.5)). Combining data from Italy and Sweden we only observed a significant association between long-term exposure to NOx and decreased levels of circulating IL-8. We observed some indication for perturbations in the inflammatory markers due to long-term exposure to NOx. Effects were stronger in Italy than in Sweden, potentially reflecting the difference in air pollution levels between the two cohorts. Copyright © 2015 Elsevier Ltd. All rights reserved.

Diverse Long-Term Variability of Five Candidate High-Mass X-Ray Binaries from Swift Burst Alert Telescope Observations

NASA Technical Reports Server (NTRS)

Corbet, Robin H. D.; Coley, Joel B.; Krimm, Hans A.

2017-01-01

We present an investigation of long-term modulation in the X-ray light curves of five little-studied candidate high-mass X-ray binaries using the Swift Burst Alert Telescope (SWIFT-BAT). IGR J14488-5942 and AX J1700.2-4220 show strong modulation at periods of 49.6 and 44 days, respectively, which are interpreted as orbital periods of Be star systems. For IGR J14488-5942, observations with the Swift X-ray Telescope show a hint of pulsations at 33.4 seconds. For AX J1700.2-4220, 54 second-pulsations were previously found with XMM-Newton. Swift J1816.7-1613 exhibits complicated behavior. The strongest peak in the power spectrum is at a period near 150 days, but this conflicts with a determination of a period of 118.5 days by La Parola et al. AX J1820.5-1434 has been proposed to exhibit modulation near 54 days, but the extended BAT observations suggest modulation at slightly longer than double this at approximately 111 days. There appears to be a long-term change in the shape of the modulation near 111 days, which may explain the apparent discrepancy. The X-ray pulsar XTE J1906+090,which was previously proposed to be a Be star system with an orbital period of approximately 30 days from pulse timing, shows peaks in the power spectrum at 81 and 173 days. The origins of these periods are unclear, although theymight be the orbital period and a superorbital period respectively. For all five sources, the long-term variability, together with the combination of orbital and proposed pulse periods, suggests that the sources contain Be starmass donors.

Diverse Long-term Variability of Five Candidate High-mass X-Ray Binaries from Swift Burst Alert Telescope Observations

NASA Astrophysics Data System (ADS)

Corbet, Robin H. D.; Coley, Joel B.; Krimm, Hans A.

2017-09-01

We present an investigation of long-term modulation in the X-ray light curves of five little-studied candidate high-mass X-ray binaries using the Swift Burst Alert Telescope. IGR J14488-5942 and AX J1700.2-4220 show strong modulation at periods of 49.6 and 44 days, respectively, which are interpreted as orbital periods of Be star systems. For IGR J14488-5942, observations with the Swift X-ray Telescope show a hint of pulsations at 33.4 s. For AX J1700.2-4220, 54 s pulsations were previously found with XMM-Newton. Swift J1816.7-1613 exhibits complicated behavior. The strongest peak in the power spectrum is at a period near 150 days, but this conflicts with a determination of a period of 118.5 days by La Parola et al. AX J1820.5-1434 has been proposed to exhibit modulation near 54 days, but the extended BAT observations suggest modulation at slightly longer than double this at approximately 111 days. There appears to be a long-term change in the shape of the modulation near 111 days, which may explain the apparent discrepancy. The X-ray pulsar XTE J1906+090, which was previously proposed to be a Be star system with an orbital period of ˜30 days from pulse timing, shows peaks in the power spectrum at 81 and 173 days. The origins of these periods are unclear, although they might be the orbital period and a superorbital period respectively. For all five sources, the long-term variability, together with the combination of orbital and proposed pulse periods, suggests that the sources contain Be star mass donors.

Diverse Long-Term Variability of Five Candidate High-Mass X-ray Binaries from Swift Burst Alert Telescope Observations

NASA Astrophysics Data System (ADS)

Corbet, Robin; Coley, Joel Barry; Krimm, Hans A.

2017-08-01

We present an investigation of long-term modulation in the X-ray light curves of five little-studied candidate high-mass X-ray binaries using the Swift Burst Alert Telescope. IGR J14488-5942 and AX J1700.2-4220 show strong modulation at periods of 49.6 and 44 days, respectively, which are interpreted as orbital periods of Be star systems. For IGR J14488-5942, observations with Swift X-ray Telescope show a hint of pulsations at 33.4 s. For AX J1700.2-4220, 54 s pulsations were previously found with XMM-Newton. Swift J1816.7-1613 exhibits complicated behavior. The strongest peak in the power spectrum is at a period near 150 days, but this conflicts with a determination of a period of 118.5 days by La Parola et al. (2014). AX J1820.5-1434 has been proposed to exhibit modulation near 54 days, but the extended BAT observations suggest modulation at slightly longer than double this at approximately 111 days. There appears to be a long-term change in the shape of the modulation near 111 days, which may explain the apparent discrepancy. The X-ray pulsar XTE J1906+090, which was previously proposed to be a Be star system with an orbital period of ˜30 days from pulse timing, shows peaks in the power spectrum at 81 and 173 days. The origins of these periods are unclear, although they might be the orbital period and a superorbital period respectively. For all five sources, the long-term variability, together with the combination of orbital and proposed pulse periods, suggests that the sources contain Be star mass donors.

Near-Term Actions to Address Long-Term Climate Risk

NASA Astrophysics Data System (ADS)

Lempert, R. J.

2014-12-01

Addressing climate change requires effective long-term policy making, which occurs when reflecting on potential events decades or more in the future causes policy makers to choose near-term actions different than those they would otherwise pursue. Contrary to some expectations, policy makers do sometimes make such long-term decisions, but not as commonly and successfully as climate change may require. In recent years however, the new capabilities of analytic decision support tools, combined with improved understanding of cognitive and organizational behaviors, has significantly improved the methods available for organizations to manage longer-term climate risks. In particular, these tools allow decision makers to understand what near-term actions consistently contribute to achieving both short- and long-term societal goals, even in the face of deep uncertainty regarding the long-term future. This talk will describe applications of these approaches for infrastructure, water, and flood risk management planning, as well as studies of how near-term choices about policy architectures can affect long-term greenhouse gas emission reduction pathways.

Data Homogenization of the NOAA Long-Term Ozonesonde Records

NASA Astrophysics Data System (ADS)

Johnson, B.; Cullis, P.; Sterling, C. W.; Jordan, A. F.; Hall, E. G.; Petropavlovskikh, I. V.; Oltmans, S. J.; Mcconville, G.

2015-12-01

The NOAA long term balloon-borne ozonesonde sites at Boulder, Colorado; Hilo, Hawaii; and South Pole Station, Antarctica have measured weekly ozone profiles for more than 3 decades. The ozonesonde consists of an electrochemical concentration cell (ECC) sensor interfaced with a weather radiosonde which transmits high resolution ozone and meteorological data during ascent from the surface to 30-35 km altitude. During this 30 year time period there have been several model changes in the commercially available ECC ozonesondes and radiosondes as well as three adjustments in the ozone sensor solution composition at NOAA. These changes were aimed at optimizing the ozonesonde performance. Organized intercomparison campaigns conducted at the environmental simulation facility at the Research Centre Juelich, Germany and international field site testing have been the primary process for assessing new designs, instruments, or sensor solution changes and developing standard operating procedures. NOAA has also performed in-house laboratory tests and launched 28 dual ozonesondes at various sites since 1994 to provide further comparison data to determine the optimum homogenized data set. The final homogenization effort involved reviewing and editing several thousand individual ozonesonde profiles followed by applying the optimum correction algorithms for changes in type of sensor solution composition. The results of improved data sets will be shown with long term trends and uncertainties at various altitude levels.

Globally Increased Crop Growth and Cropping Intensity from the Long-Term Satellite-Based Observations

NASA Astrophysics Data System (ADS)

Chen, Bin

2018-04-01

Understanding the spatiotemporal change trend of global crop growth and multiple cropping system under climate change scenarios is a critical requirement for supporting the food security issue that maintains the function of human society. Many studies have predicted the effects of climate changes on crop production using a combination of filed studies and models, but there has been limited evidence relating decadal-scale climate change to global crop growth and the spatiotemporal distribution of multiple cropping system. Using long-term satellite-derived Normalized Difference Vegetation Index (NDVI) and observed climate data from 1982 to 2012, we investigated the crop growth trend, spatiotemporal pattern trend of agricultural cropping intensity, and their potential correlations with respect to the climate change drivers at a global scale. Results show that 82.97 % of global cropland maximum NDVI witnesses an increased trend while 17.03 % of that shows a decreased trend over the past three decades. The spatial distribution of multiple cropping system is observed to expand from lower latitude to higher latitude, and the increased cropping intensity is also witnessed globally. In terms of regional major crop zones, results show that all nine selected zones have an obvious upward trend of crop maximum NDVI (p < 0.001), and as for climatic drivers, the gradual temperature and precipitation changes have had a measurable impact on the crop growth trend.

A multifaceted approach to education, observation, and feedback in a successful hand hygiene campaign.

PubMed

Doron, Shira I; Kifuji, Kayoko; Hynes, Brooke Tyson; Dunlop, Dan; Lemon, Tricia; Hansjosten, Karen; Cheung, Teresa; Curley, Barbara; Snydman, David R; Fairchild, David G

2011-01-01

Prevention of health care-associated infections starts with scrupulous hand hygiene (HH). Improving HH compliance is a major target for the World Health Organization Patient Safety Challenge and is one of The Joint Commission's National Patient Safety Goals. Yet, adherence to HH protocols is generally poor for health care professionals, despite interventions designed to improve compliance. At Tufts Medical Center (Boston), HH compliance rates were consistently low despite the presence of a traditional HH campaign that used communication and education. A comprehensive program incorporated strong commitment by hospital leadership-who were actively involved in responsibilities previously only performed by infection preventionists and quality and patient safety staff-dedication of financial resources, including securing a grant; collaborating with a private advertising firm in a marketing campaign; and employing a multifaceted approach to education, observation, and feedback. This campaign resulted in a rapid and sustained improvement in HH compliance: Compared with the mean HH compliance rate for the six months before the campaign (72%), postcampaign HH compliance (mean = 94%) was significantly greater (p < .0001). Factors contributing to the success of the campaign included the development of the marketing campaign to fit this academic medical center's particular culture, strong support from the medical center leadership, a multifaceted educational approach, and monthly feedback on HH compliance. A comprehensive campaign resulted in rapid and sustained improvement in HH compliance at an academic medical center after traditional communication and education strategies failed to improve HH performance.

Long-term phenotypic evolution of bacteria.

PubMed

Plata, Germán; Henry, Christopher S; Vitkup, Dennis

2015-01-15

For many decades comparative analyses of protein sequences and structures have been used to investigate fundamental principles of molecular evolution. In contrast, relatively little is known about the long-term evolution of species' phenotypic and genetic properties. This represents an important gap in our understanding of evolution, as exactly these proprieties play key roles in natural selection and adaptation to diverse environments. Here we perform a comparative analysis of bacterial growth and gene deletion phenotypes using hundreds of genome-scale metabolic models. Overall, bacterial phenotypic evolution can be described by a two-stage process with a rapid initial phenotypic diversification followed by a slow long-term exponential divergence. The observed average divergence trend, with approximately similar fractions of phenotypic properties changing per unit time, continues for billions of years. We experimentally confirm the predicted divergence trend using the phenotypic profiles of 40 diverse bacterial species across more than 60 growth conditions. Our analysis suggests that, at long evolutionary distances, gene essentiality is significantly more conserved than the ability to utilize different nutrients, while synthetic lethality is significantly less conserved. We also find that although a rapid phenotypic evolution is sometimes observed within the same species, a transition from high to low phenotypic similarity occurs primarily at the genus level.

Long-term observing system for the oceanic regime of Filchner-Ronne Ice Shelf, Antarctica

NASA Astrophysics Data System (ADS)

Østerhus, Svein; Schröder, Michael; Hellmer, Hartmunt; Darelius, Elin; Nicholls, Keith; Makinson, Keith

2014-05-01

Long term observations of the flow of dense waters from their area of formation to the abyss of the World Ocean, and the return flow of warm waters, are central to climate research. For the Weddell Sea an important component of such a system entails monitoring the formation of High Salinity Shelf Water (HSSW) on the continental shelf north of Ronne Ice Front, the transformation to Ice Shelf Water (ISW) beneath the floating Filchner-Ronne ice shelf, and the flux of ISW overflowing the shelf break to the deep Weddell Sea. Equally important is the return flow of warm water toward the Filchner-Ronne Ice Shelf system. AWI, BAS and UNI/UIB operate a number of monitoring stations in the southern Weddell Sea. The systems build upon techniques and methods developed over several decades and have a proven record of high data return. Here we present plans for extending, integrating and operating the existing long term observatories to increase our knowledge of the natural variability of the ocean-ice shelf system, and to allow early identification of possible changes of regional or global importance. The S2 observatory at the Filchner sill was established in 1977 and continues to deliver the longest existing marine time series from Antarctica. As a key site for monitoring the ISW overflow S2 is a part of the global net of monitoring sites under CLIVAR Southern Ocean Observing System (SOOS) and OceanSITES. The existing S2 observatory consists of a sub-surface mooring carrying sensors for current velocity, temperature, salinity and dissolved oxygen measurements. Observations at the Filchner sill also show a seasonal inflow of relatively warm water that is able to reach Filchner Ice Front. New model results indicate that this flow of water might increase in the future and we have deployed a number of instrumented moorings in the Filchner Depression to estimate the heat flux towards the ice shelf. In 1999 we established Site 5 on Ronne Ice Shelf using a hot-water drill to access

Infectious disease control in a long-term refugee camp: the role of epidemiologic surveillance and investigation.

PubMed Central

Elias, C J; Alexander, B H; Sokly, T

1990-01-01

This report demonstrates the role of epidemiologic surveillance and investigation in the control of infectious diseases in a long-term refugee camp. The applications of simple epidemiologic methods in a refugee camp on the Thai-Cambodian border are described for a one-year period. The development of a Health Information Office facilitated the collection of demographic and vital statistics data, administration of a disease surveillance system, regular monitoring of hospital and outpatient discharge diagnoses, and investigation of disease outbreaks. This office also organized community health education campaigns and disease control efforts. Examples of specific disease investigations are provided to demonstrate the utility of epidemiologic surveillance in the control of infectious disease. We conclude that simple epidemiologic methods play an important role in health planning in long-term refugee camps. PMID:2356906

A Long-term study of three rotating radio transients

NASA Astrophysics Data System (ADS)

Bhattacharyya, B.; Lyne, A. G.; Stappers, B. W.; Weltevrede, P.; Keane, E. F.; McLaughlin, M. A.; Kramer, M.; Jordan, C.; Bassa, C.

2018-04-01

We present the longest-term timing study so far of three Rotating Radio Transients (RRATs) - J1819-1458, J1840-1419 and J1913+1330 - performed using the Lovell, Parkes and Green Bank telescopes over the past decade. We study long-term and short-term variations of the pulse emission rate from these RRATs and report a marginal indication of a long-term increase in pulse detection rate over time for PSR J1819-1458 and J1913+1330. For PSR J1913+1330, we also observe a two orders of magnitude variation in the observed pulse detection rates across individual epochs, which may constrain the models explaining the origin of RRAT pulses. PSR J1913+1330 is also observed to exhibit a weak persistent emission mode. We investigate the post-glitch timing properties of J1819-1458 (the only RRAT for which glitches are observed) and discuss the implications for possible glitch models. Its post-glitch over-recovery of the frequency derivative is magnetar-like and similar behaviour is only observed for two other pulsars, both of which have relatively high magnetic field strengths. Following the over-recovery we also observe that some fraction of the pre-glitch frequency derivative is gradually recovered.

Viability of long-term gene therapy in the cochlea.

PubMed

Atkinson, Patrick J; Wise, Andrew K; Flynn, Brianna O; Nayagam, Bryony A; Richardson, Rachael T

2014-04-22

Gene therapy has been investigated as a way to introduce a variety of genes to treat neurological disorders. An important clinical consideration is its long-term effectiveness. This research aims to study the long-term expression and effectiveness of gene therapy in promoting spiral ganglion neuron survival after deafness. Adenoviral vectors modified to express brain derived neurotrophic factor or neurotrophin-3 were unilaterally injected into the guinea pig cochlea one week post ototoxic deafening. After six months, persistence of gene expression and significantly greater neuronal survival in neurotrophin-treated cochleae compared to the contralateral cochleae were observed. The long-term gene expression observed indicates that gene therapy is potentially viable; however the degeneration of the transduced cells as a result of the original ototoxic insult may limit clinical effectiveness. With further research aimed at transducing stable cochlear cells, gene therapy may be an efficacious way to introduce neurotrophins to promote neuronal survival after hearing loss.

[Development of an incubation system for an inverted microscopy for long-term observation of cell cultures using chamber slides].

PubMed

Feicht, W; Buchner, A; Riesenberg, R

2001-05-01

Trifunctional bispecific antibodies open up new immunological possibilities in tumour treatment. Prior to clinical application, comprehensive investigations using animal models and in vitro examinations need to be done. To investigate long-term interactions between various immunologically active blood cells and individual tumour cells in the presence of antibodies, we developed an incubation system for experimental cell cultures on an inverted microscope. The system consists of a perspex box with a central moisture chamber with integrated water reservoir, external air circulation heating, and a CO2 supply. The sterile cell cultures are located in the wells of a slide positioned within a depression in the water reservoir. The newly developed incubation system enables continuous observation over the long term of experiments under optimal cell cultures conditions in combination with modern video techniques.

Short-term and long-term attentional biases to frequently encountered target features.

PubMed

Sha, Li Z; Remington, Roger W; Jiang, Yuhong V

2017-07-01

It has long been known that frequently occurring targets are attended better than infrequent ones in visual search. But does this frequency-based attentional prioritization reflect momentary or durable changes in attention? Here we observed both short-term and long-term attentional biases for visual features as a function of different types of statistical associations between the targets, distractors, and features. Participants searched for a target, a line oriented horizontally or vertically among diagonal distractors, and reported its length. In one set of experiments we manipulated the target's color probability: Targets were more often in Color 1 than in Color 2. The distractors were in other colors. Participants found Color 1 targets more quickly than Color 2 targets, but this preference disappeared immediately when the target's color became random in the subsequent testing phase. In the other set of experiments, we manipulated the diagnostic values of the two colors: Color 1 was more often a target than a distractor; Color 2 was more often a distractor than a target. Participants found Color 1 targets more quickly than Color 2 targets. Importantly, and in contrast to the first set of experiments, the featural preference was sustained in the testing phase. These results suggest that short-term and long-term attentional biases are products of different statistical information. Finding a target momentarily activates its features, inducing short-term repetition priming. Long-term changes in attention, on the other hand, may rely on learning diagnostic features of the targets.

Observation-based source terms in the third-generation wave model WAVEWATCH

NASA Astrophysics Data System (ADS)

Zieger, Stefan; Babanin, Alexander V.; Erick Rogers, W.; Young, Ian R.

2015-12-01

Measurements collected during the AUSWEX field campaign, at Lake George (Australia), resulted in new insights into the processes of wind wave interaction and whitecapping dissipation, and consequently new parameterizations of the input and dissipation source terms. The new nonlinear wind input term developed accounts for dependence of the growth on wave steepness, airflow separation, and for negative growth rate under adverse winds. The new dissipation terms feature the inherent breaking term, a cumulative dissipation term and a term due to production of turbulence by waves, which is particularly relevant for decaying seas and for swell. The latter is consistent with the observed decay rate of ocean swell. This paper describes these source terms implemented in WAVEWATCH III ®and evaluates the performance against existing source terms in academic duration-limited tests, against buoy measurements for windsea-dominated conditions, under conditions of extreme wind forcing (Hurricane Katrina), and against altimeter data in global hindcasts. Results show agreement by means of growth curves as well as integral and spectral parameters in the simulations and hindcast.

Long-term MODIS observations of cyanobacterial dynamics in Lake Taihu: Responses to nutrient enrichment and meteorological factors

PubMed Central

Shi, Kun; Zhang, Yunlin; Zhou, Yongqiang; Liu, Xiaohan; Zhu, Guangwei; Qin, Boqiang; Gao, Guang

2017-01-01

We developed and validated an empirical model for estimating chlorophyll a concentrations (Chla) in Lake Taihu to generate a long-term Chla and algal bloom area time series from MODIS-Aqua observations for 2003 to 2013. Then, based on the long-term time series data, we quantified the responses of cyanobacterial dynamics to nutrient enrichment and climatic conditions. Chla showed substantial spatial and temporal variability. In addition, the annual mean cyanobacterial surface bloom area exhibited an increasing trend across the entire lake from 2003 to 2013, with the exception of 2006 and 2007. High air temperature and phosphorus levels in the spring can prompt cyanobacterial growth, and low wind speeds and low atmospheric pressure levels favor cyanobacterial surface bloom formation. The sensitivity of cyanobacterial dynamics to climatic conditions was found to vary by region. Our results indicate that temperature is the most important factor controlling Chla inter-annual variability followed by phosphorus and that air pressure is the most important factor controlling cyanobacterial surface bloom formation followed by wind speeds in Lake Taihu. PMID:28074871

Origin of particulate matter and gaseous precursors in the Paris Megacity: Results from intensive campaigns, long term measurements and modelling

NASA Astrophysics Data System (ADS)

Beekmann, Matthias; Petetin, Hervé; Zhang, Qijie; Prevot, André S. H.; Sciare, Jean; Gros, Valérie; Ghersi, Véronique; Rosso, Amandine; Crippa, Monica; Zotter, Peter; Freutel, Fredericke; Poulain, Laurent; Freney, Evelyne; Sellegri, Karine; Drewnick, Frank; Borbon, Agnès; Wiedensohler, Aflred; Pandis, Spyros N.; Baltensperger, Urs

2016-04-01

Uncertainties on the origin of primary and secondary particulate matter and its gaseous precursors in megacities is still large and needs to be reduced. A detailed characterization of air quality in Paris (France), a megacity of more than 10 million inhabitants, during two one month intensive campaigns (MEGAPOLI) and from additional one year observations (PARTICULATE and FRANCIPOL), revealed that about 70% of the fine particulate matter (PM) at urban background is transported on average into the megacity from upwind regions. While advection of sulfate is well documented for other megacities, there was a surprisingly high contribution from long-range transport for both nitrate and organic aerosol. The data set of urban local and advected PM concentrations in the Paris area were used for a thorough evaluation of the CHIMERE model and revealed error compensation for the local and advected components of organic matter and nitrate. During spring time, CHIMERE simulations overestimate the sensitivity of ammonium nitrate peaks to NH3, because (i) they underestimate the urban background NH3 levels, probably due to neglecting enhanced NH3 emissions for larger temperatures, and because they overestimate HNO3. However, from an ensemble of mobile Max-DOAS NO2 column and airborne NOy measurements around Paris, no clear sign on a NOx emission bias in the TNO-Airparif data set was made evident. The origin of organic PM was investigated by a comprehensive analysis of aerosol mass spectrometer (AMS), radiocarbon and tracer measurements during two intensive campaigns. Primary fossil fuel combustion emissions contributed less than 20% in winter and 40% in summer to carbonaceous fine PM, unexpectedly little for a megacity. Cooking activities and, during winter, residential wood burning are the major primary organic PM sources. This analysis suggests that the major part of secondary organic aerosol is of modern origin, i.e. from biogenic precursors and from wood burning. Implementation

Linking Fine-Scale Observations and Model Output with Imagery at Multiple Scales

NASA Astrophysics Data System (ADS)

Sadler, J.; Walthall, C. L.

2014-12-01

The development and implementation of a system for seasonal worldwide agricultural yield estimates is underway with the international Group on Earth Observations GeoGLAM project. GeoGLAM includes a research component to continually improve and validate its algorithms. There is a history of field measurement campaigns going back decades to draw upon for ways of linking surface measurements and model results with satellite observations. Ground-based, in-situ measurements collected by interdisciplinary teams include yields, model inputs and factors affecting scene radiation. Data that is comparable across space and time with careful attention to calibration is essential for the development and validation of agricultural applications of remote sensing. Data management to ensure stewardship, availability and accessibility of the data are best accomplished when considered an integral part of the research. The expense and logistical challenges of field measurement campaigns can be cost-prohibitive and because of short funding cycles for research, access to consistent, stable study sites can be lost. The use of a dedicated staff for baseline data needed by multiple investigators, and conducting measurement campaigns using existing measurement networks such as the USDA Long Term Agroecosystem Research network can fulfill these needs and ensure long-term access to study sites.

Ownership and utilisation of long lasting insecticide treated nets following free distribution campaign in South West Nigeria.

PubMed

Aderibigbe, Sunday Adedeji; Olatona, Foluke Adenike; Sogunro, Oluremi; Alawode, Gafar; Babatunde, Oluwole Adeyemi; Onipe, Ambrose Itopa; Bolarinwa, Oladimeji Akeem; Ameen, Hafsat Abolore; Osagbemi, Gordon Kayode; Sanya, Emmanuel Olatunde; Olarinoye, Adebunmi Oyeladun; Akande, Tanimola Makanjuola

2014-01-01

Malaria has proven to be the most horrendous and intractable amongst the health problems confronting countries in the sub-Saharan Africa. This study aims to determine the ownership and utilisation of long lasting insecticide treated nets following free distribution campaign in a state in South West Nigeria. Multi-stage sampling technique was used to recruit 2560 households spread across the 16 LGAs of the state. Interviewer administered standardized questionnaire was used for the survey. Data analysis was done using Stata 10 software. Sixty eight point six percent (68.6%) of the households had at least one under-five child living in the household while 32.6% had at least one pregnant woman living in the household. A total of 2440 (95.3%) households received LLIN during the campaign. Overall, the utilization rate for all respondents was 58.5%. Despite the fact that 2440 households received LLINs during the campaign, only 84.3% of them were seen to have hung theirs during the survey. Coverage and ownership of LLINs increased significantly following the free distribution campaign. There was a discrepancy between net possession and net use with rate of use lower than possession. Post distribution educational campaign should be incorporated into future distribution campaigns to help increase net utilisation.

ESA airborne campaigns in support of Earth Explorers

NASA Astrophysics Data System (ADS)

Casal, Tania; Davidson, Malcolm; Schuettemeyer, Dirk; Perrera, Andrea; Bianchi, Remo

2013-04-01

comprised three airborne campaigns in Greenland from April to June 2012 separated by roughly one month and preliminary results showed the instrument capability to detect ice motion. CryoVEx 2012 was a large collaborative effort to help ensure the accuracy of ESA's ice mission CryoSat. The aim of this large-scale Arctic campaign was to record sea-ice thickness and conditions of the ice exactly below the CryoSat-2 path. A range of sensors installed on different aircraft included simple cameras to get a visual record of the sea ice, laser scanners to clearly map the height of the ice, an ice-thickness sensor (EM-Bird), ESA's radar altimeter (ASIRAS) and NASA's snow and Ku-band radars, which mimic CryoSat's measurements but at a higher resolution. Preliminary results reveal the ability to detect centimetre differences between sea-ice and thin ice/water which in turn allow for the estimation of actual sea ice thickness. In support of two currently operating EE Missions: SMOS (Soil Moisture and Ocean Salinity) and GOCE (Gravity field and steady-state Ocean Circulation Explorer), DOMECair airborne campaign will take place in Antarctica, in the Dome C region during the middle of January 2013. The two main objectives are to quantify and document the spatial variability in the DOME C area, important to establish long-term cross-calibrated multi-mission L-band measurement time-series (SMOS) and fill in the gap in the high-quality gravity anomaly maps in Antarctica since airborne gravity measurements are sparse (GOCE). Key airborne instruments in the campaign are EMIRAD-2 L-band radiometer, designed and operated by DTU and a gravimeter from AWI. ESA campaigns have been fundamental and an essential part in the preparation of new Earth Observation missions, as well as in the independent validation of their measurements and quantification of error sources. For the different activities a rich variety of datasets has been recorded, are archived and users can access campaign data through the

An European framework for the long term preservation of EO data

NASA Astrophysics Data System (ADS)

Forcada, E.; Albani, M.; Beruti, V.

2009-04-01

The need for accessing historical Earth Observation (EO) data series strongly increased in the last ten years, mainly for long term science and environmental monitoring applications. This trend is likely to increase even more in the future in particular for the growing interest on global change monitoring that requires data time-series spanning 20 years and more, and for the need to support the United Nations Framework Convention on Climate Change (UNFCCC). Content of EO data archives is extending from a few years to decades and their scientific value is continuously increasing hence is well recognized the need to preserve them without time limitation and to keep the archived EO data well accessible and exploitable as they constitute a humankind asset. The large amount of new Earth Observation missions upcoming in the next years will moreover lead to a major increase of EO data volumes. This fact, together with the increased demands from the scientific user community, marks a challenge for Earth Observation satellite operators, Space Agencies and EO data providers regarding coherent data preservation and optimum availability and accessibility of the different data products. Traditionally in Europe, there has been poor cooperation in this field with no common approach for long term preservation and access to EO space data even if cooperation and sharing are key aspects to be pursued for the benefit of the user community. Single organizations have difficulties to afford data preservation in the long term that calls for the need of optimising costs and efforts, identifying commonalities. In 2006, the European Space Agency (ESA) initiated a coordination action to share among all the European (and Canadian) stakeholders a common approach to the long term preservation of Earth Observation data. During 2007, the Agency started consultations with its Member States presenting an EO Long Term Data Preservation (LTDP) strategy targeting the preservation of all European

Long-term EEG in children.

PubMed

Montavont, A; Kaminska, A; Soufflet, C; Taussig, D

2015-03-01

Long-term video-EEG corresponds to a recording ranging from 1 to 24 h or even longer. It is indicated in the following situations: diagnosis of epileptic syndromes or unclassified epilepsy, pre-surgical evaluation for drug-resistant epilepsy, follow-up of epilepsy or in cases of paroxysmal symptoms whose etiology remains uncertain. There are some specificities related to paediatric care: a dedicated pediatric unit; continuous monitoring covering at least a full 24-hour period, especially in the context of pre-surgical evaluation; the requirement of presence by the parents, technician or nurse; and stronger attachment of electrodes (cup electrodes), the number of which is adapted to the age of the child. The chosen duration of the monitoring also depends on the frequency of seizures or paroxysmal events. The polygraphy must be adapted to the type and topography of movements. It is essential to have at least an electrocardiography (ECG) channel, respiratory sensor and electromyography (EMG) on both deltoids. There is no age limit for performing long-term video-EEG even in newborns and infants; nevertheless because of scalp fragility, strict surveillance of the baby's skin condition is required. In the specific context of pre-surgical evaluation, long-term video-EEG must record all types of seizures observed in the child. This monitoring is essential in order to develop hypotheses regarding the seizure onset zone, based on electroclinical correlations, which should be adapted to the child's age and the psychomotor development. Copyright © 2015. Published by Elsevier SAS.

Long-term use of short- and long-acting nitrates in stable angina pectoris.

PubMed

Kosmicki, Marek Antoni

2009-05-01

Long-acting nitrates are effective antianginal drugs during initial treatment. However, their therapeutic value is compromised by the rapid development of tolerance during sustained therapy, which means that their clinical efficacy is decreased during long-term use. Sublingual nitroglycerin (NTG), a short-acting nitrate, is suitable for the immediate relief of angina. In patients with stable angina treated with oral long-acting nitrates, NTG maintains its full anti-ischemic effect both after initial oral ingestion and after intermittent long-term oral administration. However, NTG attenuates this effect during continuous treatment, when tolerance to oral nitrates occurs, and this is called cross-tolerance. In stable angina long-acting nitrates are considered third-line therapy because a nitrate-free interval is required to avoid the development of tolerance. Nitrates vary in their potential to induce the development of tolerance. During long-lasting nitrate therapy, except pentaerythritol tetranitrate (PETN), one can observe the development of reactive oxygen species (ROS) inside the muscular cell of a vessel wall, and these bind with nitric oxide (NO). This leads to decreased NO activity, thus, nitrate tolerance. PETN has no tendency to form ROS, and therefore during long-term PETN therapy, there is probably no tolerance or cross-tolerance, as during treatment with other nitrates.

Using Long-Term Observations of VOCs from the CARIBIC Observatory to Refine Understanding of Transport and Chemistry in the UT/LS

NASA Astrophysics Data System (ADS)

Baker, A. K.; Thorenz, U. R.; Sauvage, C.; Riede, H.; Umezawa, T.; Williams, J.; Zahn, A.; Brenninkmeijer, C. A. M.

2014-12-01

Volatile organic compounds (VOCs) are ubiquitous trace components of the atmosphere, arising from a variety of natural and anthropogenic sources. Their wide range of lifetimes and specific source signatures make VOCs useful indicators of source region, photochemical histories and transport timescales of air masses. This is particularly true of the C2-C5non-methane hydrocarbons (NMHCs), which are predominantly anthropogenic in origin, have relatively well-known emission ratios, and lifetimes ranging from days to months. NMHCs are also frequently measured in an ensemble analysis, as is the case for whole air samples collected during deployments of the CARIBIC observatory (Civil Aircraft for the Regular Investigation of the atmosphere Based on an Instrument Container; www.caribic-atmospheric.com). Since 2005 the CARIBIC observatory operates from onboard a Lufthansa Airlines A340-600, where it is deployed monthly to make detailed observations of the atmosphere during a series of 2-6 long-distance commercial flights. The container operates at aircraft cruise altitudes of 10-12 km, placing the observations primarily in the upper troposphere and lowermost stratosphere (UT/LS). There is a dearth of information about distributions of VOCs in the UT/LS, and data is generally restricted to measurements during short-term field campaigns. However, when data are available, VOC studies have proven to be well-suited to investigations in the UT/LS, where air masses are remote from sources and background air is relatively homogeneous. Here we take advantage of the over 5000 measurements of VOCs from air samples collected during nearly 10 years of CARIBIC flights in order to better understand transport and chemistry in the tropopause region. First, we use NMHC observations to identify "hot spots" for rapid transport of boundary layer air to the UT via convection or warm conveyor belts by examining the relationships of shorter-lived species to longer-lived ones and comparison to

Plasma phenomena observed in the MAP/WINE campaign

NASA Technical Reports Server (NTRS)

Friedrich, M.

1989-01-01

The wealth of plasma data gathered in the MAP/WINE campaign allows insight into the generation of electron densities on a large, and the nature of the ions on a small scale. The associated measurements of winds and charged particles help to understand the morphology of the midlatitude ionization which turns out to correlate poorly with geomagnetic activity, but at least slightly with the prevailing winds. A somewhat clearer connection seems to exist between stratospheric warmings and radio wave absorption minima. On the local scale the interpretation of the rocket measurements of positive ions was helped by simultaneous observations of temperatures and atomic oxygen. The relevance of the description winter anomaly for high latitude electron density profiles are examined.

Visual working memory buffers information retrieved from visual long-term memory.

PubMed

Fukuda, Keisuke; Woodman, Geoffrey F

2017-05-16

Human memory is thought to consist of long-term storage and short-term storage mechanisms, the latter known as working memory. Although it has long been assumed that information retrieved from long-term memory is represented in working memory, we lack neural evidence for this and need neural measures that allow us to watch this retrieval into working memory unfold with high temporal resolution. Here, we show that human electrophysiology can be used to track information as it is brought back into working memory during retrieval from long-term memory. Specifically, we found that the retrieval of information from long-term memory was limited to just a few simple objects' worth of information at once, and elicited a pattern of neurophysiological activity similar to that observed when people encode new information into working memory. Our findings suggest that working memory is where information is buffered when being retrieved from long-term memory and reconcile current theories of memory retrieval with classic notions about the memory mechanisms involved.

Long-term urethral catheterisation.

PubMed

Turner, Bruce; Dickens, Nicola

This article discusses long-term urethral catheterisation, focusing on the relevant anatomy and physiology, indications for the procedure, catheter selection and catheter care. It is important that nurses have a good working knowledge of long-term catheterisation as the need for this intervention will increase with the rise in chronic health conditions and the ageing population.

A Unified Satellite-Observation Polar Stratospheric Cloud (PSC) Database for Long-Term Climate-Change Studies

NASA Technical Reports Server (NTRS)

Fromm, Michael; Pitts, Michael; Alfred, Jerome

2000-01-01

This report summarizes the project team's activity and accomplishments during the period 12 February, 1999 - 12 February, 2000. The primary objective of this project was to create and test a generic algorithm for detecting polar stratospheric clouds (PSC), an algorithm that would permit creation of a unified, long term PSC database from a variety of solar occultation instruments that measure aerosol extinction near 1000 nm The second objective was to make a database of PSC observations and certain relevant related datasets. In this report we describe the algorithm, the data we are making available, and user access options. The remainder of this document provides the details of the algorithm and the database offering.

K2 Campaign 5 observations of pulsating subdwarf B stars: binaries and super-Nyquist frequencies

NASA Astrophysics Data System (ADS)

Reed, M. D.; Armbrecht, E. L.; Telting, J. H.; Baran, A. S.; Østensen, R. H.; Blay, Pere; Kvammen, A.; Kuutma, Teet; Pursimo, T.; Ketzer, L.; Jeffery, C. S.

2018-03-01

We report the discovery of three pulsating subdwarf B stars in binary systems observed with the Kepler space telescope during Campaign 5 of K2. EPIC 211696659 (SDSS J083603.98+155216.4) is a g-mode pulsator with a white dwarf companion and a binary period of 3.16 d. EPICs 211823779 (SDSS J082003.35+173914.2) and 211938328 (LB 378) are both p-mode pulsators with main-sequence F companions. The orbit of EPIC 211938328 is long (635 ± 146 d) while we cannot constrain that of EPIC 211823779. The p modes are near the Nyquist frequency and so we investigate ways to discriminate super- from sub-Nyquist frequencies. We search for rotationally induced frequency multiplets and all three stars appear to be slow rotators with EPIC 211696659 subsynchronous to its orbit.

Long-term memory and volatility clustering in high-frequency price changes

NASA Astrophysics Data System (ADS)

oh, Gabjin; Kim, Seunghwan; Eom, Cheoljun

2008-02-01

We studied the long-term memory in diverse stock market indices and foreign exchange rates using Detrended Fluctuation Analysis (DFA). For all high-frequency market data studied, no significant long-term memory property was detected in the return series, while a strong long-term memory property was found in the volatility time series. The possible causes of the long-term memory property were investigated using the return data filtered by the AR(1) model, reflecting the short-term memory property, the GARCH(1,1) model, reflecting the volatility clustering property, and the FIGARCH model, reflecting the long-term memory property of the volatility time series. The memory effect in the AR(1) filtered return and volatility time series remained unchanged, while the long-term memory property diminished significantly in the volatility series of the GARCH(1,1) filtered data. Notably, there is no long-term memory property, when we eliminate the long-term memory property of volatility by the FIGARCH model. For all data used, although the Hurst exponents of the volatility time series changed considerably over time, those of the time series with the volatility clustering effect removed diminish significantly. Our results imply that the long-term memory property of the volatility time series can be attributed to the volatility clustering observed in the financial time series.

Shortwave Hyperspectral Observations During MAGIC Final Campaign Summary

DOE Office of Scientific and Technical Information (OSTI.GOV)

McBride, P. J.; Marshak, A.; Yang, W.

The Marine ARM GPCI1 Investigation of Clouds (MAGIC) field campaign was initiated to improve our understanding of low-level marine clouds that have a significant influence on the Earth’s climate. The campaign was conducted using an ARM mobile facility deployed on a commercial ship traveling between Honolulu, Hawaii, and Los Angeles, California, from October 2012 to September 2013. The solar spectral flux radiometer (SSFR) was deployed on July 6, 2013, through the end of the campaign. The SSFR was calibrated and installed by Warren Gore of NASA Ames Research Center, and the data is and will be analyzed by Drs. Alexandermore » Marshak and Weidong Yang of NASA Goddard Space Flight Center, Dr. Samuel LeBlanc of NASA Ames Research Center, Dr. Sebastian Schmidt of the University of Colorado-Boulder, and Dr. Patrick McBride of Atmospheric & Space Technology Research Associates in Boulder, Colorado.« less

Long-Term Post-CABG Survival: Performance of Clinical Risk Models Versus Actuarial Predictions.

PubMed

Carr, Brendan M; Romeiser, Jamie; Ruan, Joyce; Gupta, Sandeep; Seifert, Frank C; Zhu, Wei; Shroyer, A Laurie

2016-01-01

Clinical risk models are commonly used to predict short-term coronary artery bypass grafting (CABG) mortality but are less commonly used to predict long-term mortality. The added value of long-term mortality clinical risk models over traditional actuarial models has not been evaluated. To address this, the predictive performance of a long-term clinical risk model was compared with that of an actuarial model to identify the clinical variable(s) most responsible for any differences observed. Long-term mortality for 1028 CABG patients was estimated using the Hannan New York State clinical risk model and an actuarial model (based on age, gender, and race/ethnicity). Vital status was assessed using the Social Security Death Index. Observed/expected (O/E) ratios were calculated, and the models' predictive performances were compared using a nested c-index approach. Linear regression analyses identified the subgroup of risk factors driving the differences observed. Mortality rates were 3%, 9%, and 17% at one-, three-, and five years, respectively (median follow-up: five years). The clinical risk model provided more accurate predictions. Greater divergence between model estimates occurred with increasing long-term mortality risk, with baseline renal dysfunction identified as a particularly important driver of these differences. Long-term mortality clinical risk models provide enhanced predictive power compared to actuarial models. Using the Hannan risk model, a patient's long-term mortality risk can be accurately assessed and subgroups of higher-risk patients can be identified for enhanced follow-up care. More research appears warranted to refine long-term CABG clinical risk models. © 2015 The Authors. Journal of Cardiac Surgery Published by Wiley Periodicals, Inc.

Long-Term Spectral Variability of the Spotted Star IN Com

NASA Astrophysics Data System (ADS)

Alekseev, I. Yu.; Kozlova, O. V.; Gorda, S. Yu.; Avvakumova, E. A.; Kozhevnikova, A. V.

2017-06-01

We present long-term (2004-2016) spectral observations (R = 20000) of IN Com in the regions of Hα, Hβ and He I 5876 Å lines. The unique feature of the stellar spectrum is the presence of the extended two-component emission with limits up to ± 400 km s-1 in the Hα line. Emission parameters show the rotation modulation with the stellar rotation period and a significant variability on the long-term scale. Similar emission is also observed in Hβ and He I 5876 Å lines. Our results allow us to conclude that observational emission profiles are formed in optically thin hot gas. It is a result of presence of a circumstellar gas disk around IN Com. Its size is not exceed several stellar radii. The matter for the disk is supported by stellar wind. Detected variability of Hα emission parameters shows evident relation with UBVRI photometric activity of the star. This fact allowed us to link the long-term spectral variability with cycles of stellar activity of IN Com.

Effect of aromatherapy massage on elderly patients under long-term hospitalization in Japan.

PubMed

Satou, Tadaaki; Chikama, Mizuki; Chikama, Yoshiko; Hachigo, Masato; Urayama, Haruna; Murakami, Shio; Hayashi, Shinichiro; Koikem, Kazuo

2013-03-01

To verify the effectiveness of aromatherapy massage on elderly patients under long-term hospitalization. Aromatherapy massage was performed twice a week for a total of eight times. Nursing home. Elderly women under long-term hospitalization. Questionnaire and measurement of stress marker levels (salivary amylase activity) before and after the first, fifth, and eighth aromatherapy massages. Questionnaire (Face scale, General Health Questionnaire-12 [GHQ-12]), measurement of salivary amylase activity. A decrease in stress after aromatherapy massage compared to before each massage was confirmed at all measurement times and with the stress marker. No marked reduction was observed in Face scale or saliva amylase activity as a whole over the long term, although decreasing tendencies were seen. Marked reductions in GHQ-12 were observed over the long term. Aroma massage appears likely to prove effective in reducing psychological stress among elderly patients under long-term hospitalization.

Long-term deconditioning of gas-filled surge arresters

NASA Astrophysics Data System (ADS)

Stanković, Koviljka; Brajović, Dragan; Alimpijević, Mališa; Lončar, Boris

2016-07-01

The aim of this paper is to identify parameters that influence the long-term deconditioning effect of gas-filled surge arrester (GFSA) and to provide practical recommendations for mitigating this effect. Namely, after some period of time, on order of hours or days, during which there is no activation due to overvoltage, the deconditioning of GFSA occurs. This effect was observed experimentally within the paper. The observed parameters that could influence the long-term deconditioning effect were the following: shape of voltage load, gas type, gas pressure, interelectrode distance, electrode material, electrode surface topography as well as GFSA design such as two- or three-electrode configuration. According to the results obtained, it has been shown that the occurrence of long-term deconditioning in an insulating system, insulated by a noble gas at a subpressure and with small interelectrode distances, is a phenomenon that always occurs when the insulating system is at rest for about an hour. It has been found that the type of noble gas does not influence the long-term deconditioning. Analysis of such insulating systems' parameters, with a prospect of being used as GFSAs, has demonstrated that this phenomenon is less pronounced at higher pressures (for the same value of the pressure (p) and interelectrode distance (d) product) and for electrodes with microscopically embossed surfaces. According to the results that were obtained by noble gases and their mixtures, as well as the results that were obtained by mixtures of SF6 gas with noble gasses, it can be claimed with confidence that the effect of the long-term deconditioning is an electrode effect. It has also been established that the deconditioning effect does not depend on the electrode material except in the case of electrodes made out of noble metals, which reduce the effect. Based on these results, it can be recommended that the working point of GFSAs be set (according to the DC breakdown voltage value) at a

Long-term care: long-term care insurance--2005. End of Year Issue Brief.

PubMed

Tanner, Rachel; Bercaw, Lawren

2005-12-31

As the "Baby Boom" generation approaches retirement, state and federal lawmakers are struggling to ensure that the nation's long-term care system will provide adequate services for the growing number of senior citizens. A 2003 Administration on Aging report predicted that the elderly population will double by 2030. Accordingly, policymakers must prepare for the impending squeeze on public health and Medicaid resources. Many consumers are exploring private long-term care insurance options as a means of preparing for the cost of eldercare. Yet, a lack of market uniformity has rendered the long-term care insurance industry somewhat difficult for consumers to decipher. In addition, senior care insurance is often costly, particularly for those over age 50.

Long-term stability of GOES-8 and -9 attitude control

NASA Astrophysics Data System (ADS)

Carr, James L.

1996-10-01

An independent audit of the in-orbit behavior of the GOES-8 and GOES-9 satellites has been conducted for the NASA/GSFC. This audit utilized star and landmark observations from the GOES imager to determine long-term histories for spacecraft attitude, orbital position, and instrument internal misalignments. The paper presents results from this audit. Long-term drifts are found in the attitude histories, whereas the misalignment histories are shown to be diurnally stable. The GOES image navigation and registration system is designed to compensate for instrument internal misalignments, and both the diurnally repeatable and drift components of the attitude. Correlations between GOES-8 and GOES-9 long-term roll and pitch drifts implicate the Earth sensor as the origin of these observed drifts. This results clearly demonstrates the enhanced registration stability to be obtained with stellar inertial attitude determination replacing or supplementing Earth sensor control on future GOES missions.

RVxK2: Simultaneous PRV Program with Kepler/K2 Campaign 16

NASA Astrophysics Data System (ADS)

Xuesong Wang, Sharon; RVxK2 team

2018-01-01

Introducing the RVxK2 program: simultaneous precise radial velocity (PRV) observations with Kepler/K2 Campaign 16, from Dec 7 2017 through Feb 26 2018 (website: rvxk2.com). K2 will provide short cadence photometric data on five carefully selected stars, including the brightest M dwarf in C16 field, a solar analog, and three bright G/K subgiants. K2 will also provide long cadence data on the next three brightest K or M dwarfs in the C16 field. Our campaign includes several precise RV instruments around the globe, including Keck/HIRES, APF, IRTF/iSHELL, SONG, MINERVA, PARAS, representing the first organized, extensive, simultaneous RV campaign with space photometry. Our primary science goal is to characterize and understand stellar jitter and stellar activity. This RV+K2 campaign will provide the community with an unprecedented dataset of RV spectra and precise photometry to study stellar jitter on a broad range of time scales, from minutes to 80 days. We will gather the first ever RV+photometry dataset aiming at characterizing stellar granulation, the most poorly understood term among all astrophysical sources of stellar jitter. This project will also enable the first asteroseismic studies with simultaneous precise RVs and photometry, while searching for planets in the brightest nearby G to M dwarfs in the field.

Ground-based observations of Saturn's auroral H3+: short- and long-term trends in thermospheric temperature

NASA Astrophysics Data System (ADS)

O'Donoghue, J.; Melin, H.; Stallard, T.; Moore, L.

2014-04-01

The observations presented here used the 10-m Keck telescope situated on Mauna Kea, Hawaii. They were designed to be an integral part of the Saturn Auroral Observing Campaign of April-May 2013 (to be published in the Icarus special issue of 2014). These overlap with observations performed by the Cassini spacecraft, Hubble space telescope and the NASA infrared telescope facility (IRTF). During the observations, Saturn's sub-solar latitude was 18 degrees, i.e. Saturn was well into northern springtime/ southern autumn. In three nights of data we have found 1) the northern hemisphere is on average ~50 K cooler than the southern. This is consistent with previous work, which suggests that magnetic field strength is inversely proportional to the total heating rate. 2) the combined northern and southern temperatures range typically between 380 and 500 K on time-scales of hours/days. 3) there may be a correlation between planetary period oscillation (PPO) phase and temperature in the northern main auroral oval.

Campaign Photometry During The 2010 Eclipse Of Epsilon Aurigae

NASA Astrophysics Data System (ADS)

Hopkins, Jeff; Stencel, R. E.

2011-01-01

Epsilon Aurigae is a long period (27.1 years) eclipsing binary star system with an eclipse that lasts nearly 2 years, but with severe ambiguities about component masses and shape. The current eclipse began on schedule in August of 2009. During the previous, 1982-1984 eclipse, an International Campaign was formed to coordinate a detailed study of the system. While that Campaign was deemed successful, the evolutionary status of the star system remained unclear. Epsilon Aurigae has been observed nearly continuously since the 1982 eclipse. The current Campaign was officially started in 2006. In addition to a Yahoo forum we have a dedicated web site and more than 18 online newsletters reporting photometry, spectroscopy, interferometry and polarimetry data. High quality UBVRIJH band photometric data since before the start of the current eclipse has been submitted. We explore the color differences among the light curves in terms of eclipse phases and archival data. At least one new model of the star system has been proposed since the current Campaign began: a low mass but very high luminosity F star plus a B star surrounded by a debris disk. The current eclipse and in particular the interferometry and spectroscopic data have caused new thoughts on defining eclipsing variable star contact points and phases of an eclipse. Second contact may not be the same point as start of totality and third contact may not be the same point as the start of egress and end of totality. In addition, the much awaited mid-eclipse brightening may or may not have appeared. This paper identifies the current Campaign contributors and the photometric data. This work was supported in part by the bequest of William Herschel Womble in support of astronomy at the University of Denver, by NSF grant 1016678 to the University of Denver.

Autonomous telemetry system by using mobile networks for a long-term seismic observation

NASA Astrophysics Data System (ADS)

Hirahara, S.; Uchida, N.; Nakajima, J.

2012-04-01

When a large earthquake occurs, it is important to know the detailed distribution of aftershocks immediately after the main shock for the estimation of the fault plane. The large amount of seismic data is also required to determine the three-dimensional seismic velocity structure around the focal area. We have developed an autonomous telemetry system using mobile networks, which is specialized for aftershock observations. Because the newly developed system enables a quick installation and real-time data transmission by using mobile networks, we can construct a dense online seismic network even in mountain areas where conventional wired networks are not available. This system is equipped with solar panels that charge lead-acid battery, and enables a long-term seismic observation without maintenance. Furthermore, this system enables a continuous observation at low costs with flat-rate or prepaid Internet access. We have tried to expand coverage areas of mobile communication and back up Internet access by configuring plural mobile carriers. A micro server embedded with Linux consists of automatic control programs of the Internet connection and data transmission. A status monitoring and remote maintenance are available via the Internet. In case of a communication failure, an internal storage can back up data for two years. The power consumption of communication device ranges from 2.5 to 4.0 W. With a 50 Ah lead-acid battery, this system continues to record data for four days if the battery charging by solar panels is temporarily unavailable.

[Radiometers performance attenuation and data correction in long-term observation of total radiation and photosynthetically active radiation in typical forest ecosystems in China].

PubMed

Zhu, Zhi-Lin; Sun, Xiao-Min; Yu, Gui-Rui; Wen, Xue-Fa; Zhang, Yi-Ping; Han, Shi-Jie; Yan, Jun-Hua; Wang, Hui-Min

2011-11-01

Based on the total radiation and photosynthetically active radiation (PAR) observations with net radiometer (CNR1) and quantum sensor (Li-190SB) in 4 ChinaFLUX forest sites (Changbaishan, Qianyanzhou, Dinghushan, and Xishuangbanna) in 2003-2008, this paper analyzed the uncertainties and the radiometers performance changes in long-term and continuous field observation. The results showed that the 98% accuracy of the total radiation measured with CNR1 (Q(cNR1)) could satisfy the technical criterion for the sites except Xishuangbanna where the Q(CNR1) was averagely about 7% lower than Q(CM11), the radiation measured with high accuracy pyranometer CM11. For most sites, though the temperature had definite effects on the performance of CNR1, the effects were still within the allowable range of the accuracy of the instrument. Besides temperature, the seasonal fog often occurred in tropical rain forests in Xishuangbanna also had effects on the performance of CNR1. Based on the long-term variations of PAR, especially its ratio to total radiation in the 4 sites, it was found that quantum sensor (Li-190SB) had obvious performance attenuation, with the mean annual attenuation rate being about 4%. To correct the observation error caused by Li-190SB, an attempt was made to give a post-correction of the PAR observations, which could basically eliminate the quantum sensor's performance attenuation due to long-term field measurement.

Asthma Medicines: Long-Term Control

MedlinePlus

... Size Email Print Share Asthma Medicines: Long-term Control Page Content Article Body Corticosteroids Synthetic versions of ... form, they are used exclusively for long-term control; they are not very effective for acute symptoms. ...

Long-term associative learning predicts verbal short-term memory performance.

PubMed

Jones, Gary; Macken, Bill

2018-02-01

Studies using tests such as digit span and nonword repetition have implicated short-term memory across a range of developmental domains. Such tests ostensibly assess specialized processes for the short-term manipulation and maintenance of information that are often argued to enable long-term learning. However, there is considerable evidence for an influence of long-term linguistic learning on performance in short-term memory tasks that brings into question the role of a specialized short-term memory system separate from long-term knowledge. Using natural language corpora, we show experimentally and computationally that performance on three widely used measures of short-term memory (digit span, nonword repetition, and sentence recall) can be predicted from simple associative learning operating on the linguistic environment to which a typical child may have been exposed. The findings support the broad view that short-term verbal memory performance reflects the application of long-term language knowledge to the experimental setting.

Predicting long-term graft survival in adult kidney transplant recipients.

PubMed

Pinsky, Brett W; Lentine, Krista L; Ercole, Patrick R; Salvalaggio, Paolo R; Burroughs, Thomas E; Schnitzler, Mark A

2012-07-01

The ability to accurately predict a population's long-term survival has important implications for quantifying the benefits of transplantation. To identify a model that can accurately predict a kidney transplant population's long-term graft survival, we retrospectively studied the United Network of Organ Sharing data from 13,111 kidney-only transplants completed in 1988- 1989. Nineteen-year death-censored graft survival (DCGS) projections were calculated and compared with the population's actual graft survival. The projection curves were created using a two-part estimation model that (1) fits a Kaplan-Meier survival curve immediately after transplant (Part A) and (2) uses truncated observational data to model a survival function for long-term projection (Part B). Projection curves were examined using varying amounts of time to fit both parts of the model. The accuracy of the projection curve was determined by examining whether predicted survival fell within the 95% confidence interval for the 19-year Kaplan-Meier survival, and the sample size needed to detect the difference in projected versus observed survival in a clinical trial. The 19-year DCGS was 40.7% (39.8-41.6%). Excellent predictability (41.3%) can be achieved when Part A is fit for three years and Part B is projected using two additional years of data. Using less than five total years of data tended to overestimate the population's long-term survival, accurate prediction of long-term DCGS is possible, but requires attention to the quantity data used in the projection method.

Long term attenuation statistics at 11.6 GHz in the three Italian Main Stations

NASA Astrophysics Data System (ADS)

Carassa, Francesco; Mauri, Mario; Paraboni, Aldo

1987-04-01

Results are presented from the 5-year attenuation-measurement campaign conducted with the SIRIO satellite at 11.6 and 17.8, which used near-continuous measurements at the lower frequency from the Italian ground stations at Fucino, Lario, and Spino d'Adda, and fewer measurements at the higher frequency from Fucino and Lario. The long-term statistics thus obtained have been applied in the design of the Italian domestic satellite system Italsat, which is to begin operating in 1989. Attention is presently given to annual worst month, time-of-day dependence, rain rate attenuation correlation, and frequency scaling statistics.

Long-term Trend of Satellite-observed Chlorophyll-a Concentration Variations in the East/Japan Sea

NASA Astrophysics Data System (ADS)

Park, J. E.; PARK, K. A.

2016-02-01

Long-term time-series of satellite ocean color data enable us to analyze the effects of climate change on ocean ecosystem through chlorophyll-a concentration as a proxy for phytoplankton biomass. In this study, we constructed a 17 year-long time-series dataset (1998-2014) of chlorophyll-a concentration by combining SeaWiFS (Obrview-2, 1997-2010) and MODIS (Aqua, 2002-present) data in the East Sea (Japan Sea). Several types of errors such as anonymously high values (a speckle error), stripe-like patterns, discrepancy originating from time gap between the two satellites were eliminated to enhance the accuracy of chlorophyll-a concentration data. The composited chlorophyll-a concentration maps, passing through the post-processing of the speckle errors, were improved significantly, by 14% of abnormal variability in maximum. Using the database, we investigated spatial and temporal variability of chlorophyll-a concentration in the East Sea. Spatial distribution of long-term trend of chlorophyll-a concentration indicated obvious distinction between northern and southern regions of the subpolar front. It revealed predominant seasonal variabilities as well as long-term changes in the timings of spring bloom. This study addresses the important role of local climate change on fast changing ecosystem of the East Sea as one of miniature oceans.

An idealised study for the long term evolution of crescentic bars

NASA Astrophysics Data System (ADS)

Chen, W. L.; Dodd, N.; Tiessen, M. C. H.; Calvete, D.

2018-01-01

An idealised study that identifies the mechanisms in the long term evolution of crescentic bar systems in nature is presented. Growth to finite amplitude (i.e., equilibration, sometimes referred to as saturation) and higher harmonic interaction are hypothesised to be the leading nonlinear effects in long-term evolution of these systems. These nonlinear effects are added to a linear stability model and used to predict crescentic bar development along a beach in Duck, North Carolina (USA) over a 2-month period. The equilibration prolongs the development of bed patterns, thus allowing the long term evolution. Higher harmonic interaction enables the amplitude to be transferred from longer to shorter lengthscales, which leads to the dominance of shorter lengthscales in latter post-storm stages, as observed at Duck. The comparison with observations indicates the importance of higher harmonic interaction in the development of nearshore crescentic bar systems in nature. Additionally, it is concluded that these nonlinear effects should be included in models simulating the development of different bed patterns, and that this points a way forward for long-term morphodynamical modelling in general.

Simultaneous lidar observations of the water vapor and ozone signatures of a stratospheric intrusion during the MOHAVE-2009 campaign

NASA Astrophysics Data System (ADS)

Leblanc, T.; McDermid, I. S.; Pérot, K.

2010-12-01

Ozone and water vapor signatures of a stratospheric intrusion were simultaneously observed by the Jet Propulsion Laboratory lidars located at Table Mountain Facility, California (TMF, 34.4N, 117.7W) during the Measurements of Humidity in the Atmosphere and Validation Experiments (MOHAVE-2009) campaign in October 2009. These observations are placed in the context of the meridional displacement and folding of the tropopause, and resulting contrast in the properties of the air masses sampled by lidar. The lidar observations are supported by model data, specifically potential vorticity fields advected by the high-resolution transport model MIMOSA, and by 10-day backward isentropic trajectories. The ozone and water vapor anomalies measured by lidar were largely anti-correlated, and consistent with the assumption of a wet and ozone-poor subtropical upper troposphere, and a dry and ozone-rich extra-tropical lowermost stratosphere. However, it is shown that this anti-correlation relation collapsed just after the stratospheric intrusion event of October 20, suggesting mixed air embedded along the subtropical jet stream and sampled by lidar during its displacement south of TMF (tropopause fold). The ozone-PV expected positive correlation relation held strongly throughout the measurement period, including when a lower polar stratospheric filament passed over TMF just after the stratospheric intrusion. The numerous highly-correlated signatures observed during this event demonstrate the strong capability of the water vapor and ozone lidars at TMF, and provide new confidence in the future detection by lidar of long-term variability of water vapor and ozone in the Upper Troposphere-Lower Stratosphere (UTLS).

Common Calibration Source for Monitoring Long-term Ozone Trends

NASA Technical Reports Server (NTRS)

Kowalewski, Matthew

2004-01-01

Accurate long-term satellite measurements are crucial for monitoring the recovery of the ozone layer. The slow pace of the recovery and limited lifetimes of satellite monitoring instruments demands that datasets from multiple observation systems be combined to provide the long-term accuracy needed. A fundamental component of accurately monitoring long-term trends is the calibration of these various instruments. NASA s Radiometric Calibration and Development Facility at the Goddard Space Flight Center has provided resources to minimize calibration biases between multiple instruments through the use of a common calibration source and standardized procedures traceable to national standards. The Facility s 50 cm barium sulfate integrating sphere has been used as a common calibration source for both US and international satellite instruments, including the Total Ozone Mapping Spectrometer (TOMS), Solar Backscatter Ultraviolet 2 (SBUV/2) instruments, Shuttle SBUV (SSBUV), Ozone Mapping Instrument (OMI), Global Ozone Monitoring Experiment (GOME) (ESA), Scanning Imaging SpectroMeter for Atmospheric ChartographY (SCIAMACHY) (ESA), and others. We will discuss the advantages of using a common calibration source and its effects on long-term ozone data sets. In addition, sphere calibration results from various instruments will be presented to demonstrate the accuracy of the long-term characterization of the source itself.

Long-term Outcomes of Bariatric Surgery: A National Institutes of Health Symposium

PubMed Central

Courcoulas, Anita P.; Yanovski, Susan Z.; Bonds, Denise; Eggerman, Thomas L.; Horlick, Mary; Staten, Myrlene A.; Arterburn, David E.

2017-01-01

Importance The clinical evidence base demonstrating bariatric surgery’s health benefits is much larger than it was when the NIH last held a Consensus Panel in 1991. Still, it remains unclear whether ongoing studies will address critical questions about long-term complication rates and the sustainability of weight loss and comorbidity control. Objective The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the National Heart, Lung, and Blood Institute (NHLBI) convened a multidisciplinary workshop in May 2013 to summarize the current state of knowledge of bariatric surgery, review research findings on the long-term outcomes of bariatric surgery, and establish priorities for future research directions. Evidence Review The evidence presented at the workshop was selected by the planning committee for both its quality and duration of follow up. The data review emphasized RCTs and large observational studies with long-term follow up, with or without a control group. Findings Several small RCTs showed greater weight loss and T2DM remission compared to non-surgical treatments within the first 2 years of follow-up after bariatric surgery. Large, long-term observational studies show durable (>5 years) weight loss, diabetes and lipid improvements with bariatric surgery. Still unclear are predictors of outcomes, long-term complications, long-term survival, micro- and macro-vascular events, mental health outcomes, and costs. The studies needed to address these knowledge gaps would be expensive and logistically difficult to perform. Conclusions and Relevance High-quality evidence shows that bariatric surgical procedures result in greater weight loss than non-surgical treatments and are more effective at inducing initial T2DM remission in obese patients. More information is needed about the long term durability of comorbidity control and complications after bariatric procedures and this evidence will most likely come from carefully designed

Long-term observations of the background aerosol at Cabauw, The Netherlands.

PubMed

Mamali, D; Mikkilä, J; Henzing, B; Spoor, R; Ehn, M; Petäjä, T; Russchenberg, H; Biskos, G

2018-06-01

Long-term measurements of PM 2.5 mass concentrations and aerosol particle size distributions from 2008 to 2015, as well as hygroscopicity measurements conducted over one year (2008-2009) at Cabauw, The Netherlands, are compiled here in order to provide a comprehensive dataset for understanding the trends and annual variabilities of the atmospheric aerosol in the region. PM 2.5 concentrations have a mean value of 14.4μgm -3 with standard deviation 2.1μgm -3 , and exhibit an overall decreasing trend of -0.74μgm -3 year -1 . The highest values are observed in winter and spring and are associated with a shallower boundary layer and lower precipitation, respectively, compared to the rest of the seasons. Number concentrations of particles smaller than 500nm have a mean of 9.2×10 3 particles cm -3 and standard deviation 4.9×10 3 particles cm -3 , exhibiting an increasing trend between 2008 and 2011 and a decreasing trend from 2013 to 2015. The particle number concentrations exhibit highest values in spring and summer (despite the increased precipitation) due to the high occurrence of nucleation-mode particles, which most likely are formed elsewhere and are transported to the observation station. Particle hygroscopicity measurements show that, independently of the air mass origin, the particles are mostly externally mixed with the more hydrophobic mode having a mean hygroscopic parameter κ of 0.1 while for the more hydrophilic mode κ is 0.35. The hygroscopicity of the smaller particles investigated in this work (i.e., particles having diameters of 35nm) appears to increase during the course of the nucleation events, reflecting a change in the chemical composition of the particles. Copyright © 2017 Elsevier B.V. All rights reserved.

Visual working memory buffers information retrieved from visual long-term memory

PubMed Central

Fukuda, Keisuke; Woodman, Geoffrey F.

2017-01-01

Human memory is thought to consist of long-term storage and short-term storage mechanisms, the latter known as working memory. Although it has long been assumed that information retrieved from long-term memory is represented in working memory, we lack neural evidence for this and need neural measures that allow us to watch this retrieval into working memory unfold with high temporal resolution. Here, we show that human electrophysiology can be used to track information as it is brought back into working memory during retrieval from long-term memory. Specifically, we found that the retrieval of information from long-term memory was limited to just a few simple objects’ worth of information at once, and elicited a pattern of neurophysiological activity similar to that observed when people encode new information into working memory. Our findings suggest that working memory is where information is buffered when being retrieved from long-term memory and reconcile current theories of memory retrieval with classic notions about the memory mechanisms involved. PMID:28461479

Long-term changes in lower tropospheric baseline ozone concentrations: Comparing chemistry-climate models and observations at northern midlatitudes

NASA Astrophysics Data System (ADS)

Parrish, D. D.; Lamarque, J.-F.; Naik, V.; Horowitz, L.; Shindell, D. T.; Staehelin, J.; Derwent, R.; Cooper, O. R.; Tanimoto, H.; Volz-Thomas, A.; Gilge, S.; Scheel, H.-E.; Steinbacher, M.; Fröhlich, M.

2014-05-01

Two recent papers have quantified long-term ozone (O3) changes observed at northern midlatitude sites that are believed to represent baseline (here understood as representative of continental to hemispheric scales) conditions. Three chemistry-climate models (NCAR CAM-chem, GFDL-CM3, and GISS-E2-R) have calculated retrospective tropospheric O3 concentrations as part of the Atmospheric Chemistry and Climate Model Intercomparison Project and Coupled Model Intercomparison Project Phase 5 model intercomparisons. We present an approach for quantitative comparisons of model results with measurements for seasonally averaged O3 concentrations. There is considerable qualitative agreement between the measurements and the models, but there are also substantial and consistent quantitative disagreements. Most notably, models (1) overestimate absolute O3 mixing ratios, on average by 5 to 17 ppbv in the year 2000, (2) capture only 50% of O3 changes observed over the past five to six decades, and little of observed seasonal differences, and (3) capture 25 to 45% of the rate of change of the long-term changes. These disagreements are significant enough to indicate that only limited confidence can be placed on estimates of present-day radiative forcing of tropospheric O3 derived from modeled historic concentration changes and on predicted future O3 concentrations. Evidently our understanding of tropospheric O3, or the incorporation of chemistry and transport processes into current chemical climate models, is incomplete. Modeled O3 trends approximately parallel estimated trends in anthropogenic emissions of NOx, an important O3 precursor, while measured O3 changes increase more rapidly than these emission estimates.

Trend analysis of evapotranspiration over India: Observed from long-term satellite measurements

NASA Astrophysics Data System (ADS)

Goroshi, Sheshakumar; Pradhan, Rohit; Singh, Raghavendra P.; Singh, K. K.; Parihar, Jai Singh

2017-12-01

Owing to the lack of consistent spatial time series data on actual evapotranspiration ( ET), very few studies have been conducted on the long-term trend and variability in ET at a national scale over the Indian subcontinent. The present study uses biome specific ET data derived from NOAA satellite's advanced very high resolution radiometer to investigate the trends and variability in ET over India from 1983 to 2006. Trend analysis using the non-parametric Mann-Kendall test showed that the domain average ET decreased during the period at a rate of 0.22 mm year^{-1}. A strong decreasing trend (m = -1.75 mm year^{-1}, F = 17.41, P 0.01) was observed in forest regions. Seasonal analyses indicated a decreasing trend during southwest summer monsoon (m= -0.320 mm season^{-1} year^{-1}) and post-monsoon period (m= -0.188 mm season^{-1 } year^{-1}). In contrast, an increasing trend was observed during northeast winter monsoon (m = 0.156 mm season^{-1 } year^{-1}) and pre-monsoon (m = 0.068 mm season^{-1 } year^{-1}) periods. Despite an overall net decline in the country, a considerable increase ( 4 mm year^{-1}) was observed over arid and semi-arid regions. Grid level correlation with various climatic parameters exhibited a strong positive correlation (r >0.5) of ET with soil moisture and precipitation over semi-arid and arid regions, whereas a negative correlation (r -0.5) occurred with temperature and insolation in dry regions of western India. The results of this analysis are useful for understanding regional ET dynamics and its relationship with various climatic parameters over India. Future studies on the effects of ET changes on the hydrological cycle, carbon cycle, and energy partitioning are needed to account for the feedbacks to the climate.

New Horizons: Long-Range Kuiper Belt Targets Observed by the Hubble Space Telescope

NASA Technical Reports Server (NTRS)

Benecchi, S. D.; Noll, K. S.; Weaver, H. A.; Spencer, J. R.; Stern, S. A.; Buie, M. W.; Parker, A. H.

2014-01-01

We report on Hubble Space Telescope (HST) observations of three Kuiper Belt Objects (KBOs), discovered in our dedicated ground-based search campaign, that are candidates for long-range observations from the New Horizons spacecraft: 2011 epochY31, 2011 HZ102, and 2013 LU35. Astrometry with HST enables both current and future critical accuracy improvements for orbit precision, required for possible New Horizons observations, beyond what can be obtained from the ground. Photometric colors of all three objects are red, typical of the Cold Classical dynamical population within which they reside; they are also the faintest KBOs to have had their colors measured. None are observed to be binary with HST above separations of approx. 0.02 arcsec (approx. 700 km at 44 AU) and delta m less than or equal to 0.5.

Long-term outcome of severe herpes simplex encephalitis: a population-based observational study.

PubMed

Jouan, Youenn; Grammatico-Guillon, Leslie; Espitalier, Fabien; Cazals, Xavier; François, Patrick; Guillon, Antoine

2015-09-21

Herpes simplex encephalitis (HSE) is a rare disease with a poor prognosis. No recent evaluation of hospital incidence, acute mortality and morbidity is available. In particular, decompressive craniectomy has rarely been proposed in cases of life-threatening HSE with temporal herniation, in the absence of evidence. This study aimed to assess the hospital incidence and mortality of HSE, and to evaluate the characteristics, management, the potential value of decompressive craniectomy and the outcome of patients with HSE admitted to intensive care units (ICUs). Epidemiological study: we used the hospital medical and administrative discharge database to identify hospital stays, deaths and ICU admissions relating to HSE in 39 hospitals, from 2010 to 2013. Retrospective monocentric cohort: all patients with HSE admitted to the ICU of the university hospital during the study were included. The use of decompressive craniectomy and long-term outcome were analyzed. The initial brain images were analyzed blind to outcome. The hospital incidence of HSE was 1.2/100,000 inhabitants per year, 32 % of the patients were admitted to ICUs and 17 % were mechanically ventilated. Hospital mortality was 5.5 % overall, but was as high as 11.9 % in ICUs. In the monocentric cohort, 87 % of the patients were still alive after one year but half of them had moderate to severe disability. Three patients had a high intracranial pressure (ICP) with brain herniation and eventually underwent decompressive hemicraniectomy. The one-year outcome of these patients did not seem to be different from that of the other patients. It was not possible to predict brain herniation reliably from the initial brain images. HSE appears to be more frequent than historically reported. The high incidence we observed probably reflects improvements in diagnostic performance (routine use of PCR). Mortality during the acute phase and long-term disability appear to be stable. High ICP and brain herniation are rare, but must

Reforming long-term care financing through insurance

PubMed Central

Meiners, Mark R.

1988-01-01

Until recently, insurance for long-term care was not viewed as feasible. This perception has changed dramatically in the past few years. Several models of long-term care insurance have begun to be tested. Although the application of insurance principles to long-term care is still new, the emergence of private market interest in developing long-term care insurance has been a catalyst to renewed public-policy support for reforming the way we pay for long-term care. States, in particular, have become interested in developing public-private partnerships to support the emergence of long-term care insurance that could help relieve the mounting pressure on Medicaid budgets. PMID:10312962

Long term hydrographic variability near Bermuda and relation to surface forcing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joyce, T.M.

1997-11-01

This paper provides an extremely brief description of long-term hydrographic observations at Bermuda. The time series of observations near the island goes back to 1922. A secular increase of temperature of approximately 0.5 C per century in the deep water pressure range has been observed; this depth layer is the only one observed at Bermuda to have such a long-term increase. Decadal time scale fluctuations have also been identified, and are correlated to decadal variations in the Labrador Sea. The recent period of decreasing temperature at Bermuda may be a reflection of the increased cooling in the Labrador Sea inmore » recent years. 2 figs.« less

Po-Basin Atmospheric Composition during the Pegasos Field Campaign (summer 2012): Evaluation of ninfa/aodeM Simulation with In-Situ e Remote Sensing Observations

NASA Astrophysics Data System (ADS)

Landi, Tony C.; Bonafe, Giovanni; Stortini, Michele; Minguzzi, Enrico; Cristofanelli, Paolo; Marinoni, Angela; Giulianelli, Lara; Sandrini, Silvia; Gilardoni, Stefania; Rinaldi, Matteo; Ricciardelli, Isabella

2014-05-01

Within the EU project PEGASOS one of three field campaigns took place in the Po Valley during the summer of 2012. Photochemistry, particle formation, and particle properties related to diurnal evolution of the PBL were investigated through both in-situ and airborne measurements on board a Zeppelin NT air ship. In addition, 3-D air quality modeling systems were implemented over the Po valley for the summer 2012 to better characterize the atmospheric conditions, in terms of meteorological parameters and chemical composition. In this work, we present a comparison between atmospheric composition simulations carried out by the modeling system NINFA/AODEM with measurements performed during the PEGASOS field campaign for the period 13 June - 12 July 2012. NINFA (Stortini et al., 2007) is based on the chemical transport model CHIMERE (Bessagnet et al., 2008), driven by COSMO-I7, the meteorological Italian Limited Area Model, (Steppeler et al., 2003). Boundary conditions are provided by Prev'air data (www.prevair.org), and emission data input are based on regional, national and European inventory. Besides, a post-processing tool for aerosol optical properties calculation, called AODEM (Landi T. C. 2013) was implemented. Thus, predictions of Aerosol Optical Depth and aerosol extinction coefficient were also used for model comparison to vertical-resolved observations. For this experiment, NINFA/AODEM has been also evaluated by using measurements of size-segregated aerosol samples, number particles concentration and aerosol optical properties collected on hourly basis at the 3 different sampling sites representative of urban background (Bologna), rural background (San Pietro Capofiume) and remote high altitude station (Monte Cimone 2165 ma.s.l.). ). In addition, we focused on new particles formations events and long range transports from Northern Africa observed during the field campaign. References Bessagnet, Bertrand, Laurent Menut, Gabriele Curci, Alma Hodzic, Bruno

Solar cycle and long term variations of mesospheric ice layers

NASA Astrophysics Data System (ADS)

Lübken, Franz-Josef; Berger, Uwe; Kiliani, Johannes; Baumgarten, Gerd; Fiedler, Jens; Gerding, Michael

2010-05-01

Ice layers in the summer mesosphere at middle and polar latitudes, frequently called `noctilucent clouds' (NLC) or `polar mesosphere clouds'(PMC), are considered to be sensitive indicators of long term changes in the middle atmosphere. We present a summary of long term observations from the ground and from satellites and compare with results from the LIMA model (Leibniz Institute Middle Atmosphere Model). LIMA nicely reproduces mean conditions of the summer mesopause region and also mean characteristics of ice layers. LIMA nudges to ECMWF data in the troposphere and lower stratosphere which influences the background conditions in the mesosphere and thereby the morphology of ice clouds. A strong correlation between temperatures and PMC altitudes is observed. Applied to historical measurements this give s negligible temperature trends at PMC altitudes (approximately 0.01-0.02 K/y). Trace gas concentrations are kept constant in LIMA except for water vapor which is modified by variable solar radiation. Still, long term trends in temperatures and ice layer parameters are observed, consistent with observations. As will be shown, these trends originate in the stratosphere. Solar cycle effects are expected in ice layers due to variations in background temperatures and water paper. We will present results from LIMA regarding solar cycle variations and compare with NLC observations at our lidar stations in Kühlungsborn (54°N) and ALOMAR (69°N), and also with satellite measurements.

Determinants of success and sustainability of the WHO multimodal hand hygiene promotion campaign, Italy, 2007–2008 and 2014

PubMed Central

Moro, Maria Luisa; Morsillo, Filomena; Nascetti, Simona; Parenti, Mita; Allegranzi, Benedetta; Pompa, Maria Grazia; Pittet, Didier

2017-01-01

A national hand hygiene promotion campaign based on the World Health Organization (WHO) multimodal, Clean Care is Safer Care campaign was launched in Italy in 2007. One hundred seventy-five hospitals from 14 of 20 Italian regions participated. Data were collected using methods and tools provided by the WHO campaign, translated into Italian. Hand hygiene compliance, ward infrastructure, and healthcare workers’ knowledge and perception of healthcare-associated infections and hand hygiene were evaluated before and after campaign implementation. Compliance data from the 65 hospitals returning complete data for all implementation tools were analysed using a multilevel approach. Overall, hand hygiene compliance increased in the 65 hospitals from 40% to 63% (absolute increase: 23%, 95% confidence interval: 22–24%). A wide variation in hand hygiene compliance among wards was observed; inter-ward variability significantly decreased after campaign implementation and the level of perception was the only item associated with this. Long-term sustainability in 48 of these 65 hospitals was assessed in 2014 using the WHO Hand Hygiene Self-Assessment Framework tool. Of the 48 hospitals, 44 scored in the advanced/intermediate categories of hand hygiene implementation progress. The median hand hygiene compliance achieved at the end of the 2007–2008 campaign appeared to be sustained in 2014. PMID:28661390

NASA's Earth Observing Data and Information System - Near-Term Challenges

NASA Technical Reports Server (NTRS)

Behnke, Jeanne; Mitchell, Andrew; Ramapriyan, Hampapuram

2018-01-01

NASA's Earth Observing System Data and Information System (EOSDIS) has been a central component of the NASA Earth observation program since the 1990's. EOSDIS manages data covering a wide range of Earth science disciplines including cryosphere, land cover change, polar processes, field campaigns, ocean surface, digital elevation, atmosphere dynamics and composition, and inter-disciplinary research, and many others. One of the key components of EOSDIS is a set of twelve discipline-based Distributed Active Archive Centers (DAACs) distributed across the United States. Managed by NASA's Earth Science Data and Information System (ESDIS) Project at Goddard Space Flight Center, these DAACs serve over 3 million users globally. The ESDIS Project provides the infrastructure support for EOSDIS, which includes other components such as the Science Investigator-led Processing systems (SIPS), common metadata and metrics management systems, specialized network systems, standards management, and centralized support for use of commercial cloud capabilities. Given the long-term requirements, and the rapid pace of information technology and changing expectations of the user community, EOSDIS has evolved continually over the past three decades. However, many challenges remain. Challenges addressed in this paper include: growing volume and variety, achieving consistency across a diverse set of data producers, managing information about a large number of datasets, migration to a cloud computing environment, optimizing data discovery and access, incorporating user feedback from a diverse community, keeping metadata updated as data collections grow and age, and ensuring that all the content needed for understanding datasets by future users is identified and preserved.

Management training in long-term care.

PubMed

Evashwick, Connie

2002-01-01

The education of health care administrators faces its most dramatic change since the inception of the field. Recent discussions at the national level call for major overhaul of curricula and teaching modalities, including moving education to position students for evidence-based practice. This paper presents recommendations for incorporating training about chronic and long-term care into health care management curricula. It asserts that all health care management students should have a basic knowledge of the fundamental policy, operating, and financing principles of long-term care. The majority of people using the health care delivery system today, and increasingly in the future, suffer from chronic conditions. Long-term care services, although less expansive in structure, far outnumber acute care services and health plans. They will grow in the future to meet the portending demand. To maximize job opportunities and to optimize performance in any job, health care administrators need to know about the long-term care delivery system. This paper delineates critical topics pertaining to long-term care, organized according to 11 fundamental management areas in which the field is developing core competencies. The contents were derived from a year-long process of asking stakeholders in the various facets of long-term care what topics they thought were essential for administrators to know. The topics delineated in this document represent the consensus about essential knowledge that all health care administrators should have about long-term care, whether specializing in long-term care or following a more general management career. The education of health care administrators faces its most dramatic change since the inception ofthe field. Recent discussions at the national level call for major overhaul of curricula and teaching modalities, including moving education to position students to perform according to evidence-based practice. It is thus timely to consider content, as

Are you Scared Yet?: Evaluating Fear Appeal Messages in Tweets about the Tips Campaign.

PubMed

Emery, Sherry L; Szczypka, Glen; Abril, Eulàlia Puig; Kim, Yoonsang; Vera, Lisa

2014-04-01

In March 2012, the CDC launched "Tips from Former Smokers," a $54 million national campaign featuring individuals experiencing long-term health consequences of smoking. The campaign approach was based on strong evidence that anti-tobacco ads portraying fear, graphic images, and personal testimonials are associated with attitudinal and behavior change. Yet it was also controversial; critics cited the danger that viewers might reject such intensely graphic messages. Tasked with informing this debate, our study analyzes the corpus of Tips campaign-related tweets obtained via the Twitter Firehose. We provide a novel and rigorous method for media campaign evaluation within the framework of the Extended Parallel Process Model. Among the relevant Tweets, 87% showed evidence of message acceptance, while 7% exhibited message rejection.

Long-term sickness absence due to adjustment disorder.

PubMed

Catalina-Romero, C; Pastrana-Jiménez, J I; Tenas-López, M J; Martínez-Muñoz, P; Ruiz-Moraga, M; Fernández-Labandera, C; Calvo-Bonacho, E

2012-07-01

Although adjustment disorder is frequently reported in clinical settings, scientific evidence is scarce regarding its impact on sickness absence and the variables associated with sickness absence duration. To report sickness absence duration and to identify predictors of long-term sickness absence in patients with adjustment disorder. This observational, prospective study included subjects with non-work-related sickness absence (>15 days) after a diagnosis of adjustment disorder. A stepwise logistic regression analysis was conducted to identify the best predictors of long-term sickness absence (≥ 6 months). There were 1182 subjects in the final analysis. The median duration of sickness absence due to adjustment disorder was 91 days. Twenty-two per cent of the subjects reported long-term sickness absence. After multivariate analysis, comorbidity (OR = 2.23, 95% CI 1.43-3.49), age (25-34 years old versus <25 years old: OR = 2.78, 95% CI 1.27-6.07; 35-44 years old versus <25 years old: OR = 3.70, 95% CI 1.71-7.99; 45-54 years old versus <25 years old: OR = 3.58, 95% CI 1.60-8.02; ≥ 55 years old versus <25 years old: OR = 6.35, 95% CI 2.64-15.31) and occupational level (blue collar versus white collar: OR = 1.52, 95% CI 1.10-2.09) remained significantly associated with long-term sickness absence. Comorbidity was the strongest predictor. It is possible to predict long-term sickness absence due to adjustment disorder on the basis of demographic, work-related and clinical information available during the basic assessment of the patient.

Long-term urban carbon dioxide observations reveal spatial and temporal dynamics related to urban characteristics and growth

NASA Astrophysics Data System (ADS)

Mitchell, Logan E.; Lin, John C.; Bowling, David R.; Pataki, Diane E.; Strong, Courtenay; Schauer, Andrew J.; Bares, Ryan; Bush, Susan E.; Stephens, Britton B.; Mendoza, Daniel; Mallia, Derek; Holland, Lacey; Gurney, Kevin R.; Ehleringer, James R.

2018-03-01

Cities are concentrated areas of CO2 emissions and have become the foci of policies for mitigation actions. However, atmospheric measurement networks suitable for evaluating urban emissions over time are scarce. Here we present a unique long-term (decadal) record of CO2 mole fractions from five sites across Utah’s metropolitan Salt Lake Valley. We examine “excess” CO2 above background conditions resulting from local emissions and meteorological conditions. We ascribe CO2 trends to changes in emissions, since we did not find long-term trends in atmospheric mixing proxies. Three contrasting CO2 trends emerged across urban types: negative trends at a residential-industrial site, positive trends at a site surrounded by rapid suburban growth, and relatively constant CO2 over time at multiple sites in the established, residential, and commercial urban core. Analysis of population within the atmospheric footprints of the different sites reveals approximately equal increases in population influencing the observed CO2, implying a nonlinear relationship with CO2 emissions: Population growth in rural areas that experienced suburban development was associated with increasing emissions while population growth in the developed urban core was associated with stable emissions. Four state-of-the-art global-scale emission inventories also have a nonlinear relationship with population density across the city; however, in contrast to our observations, they all have nearly constant emissions over time. Our results indicate that decadal scale changes in urban CO2 emissions are detectable through monitoring networks and constitute a valuable approach to evaluate emission inventories and studies of urban carbon cycles.

Placenta previa and long-term morbidity of the term offspring.

PubMed

Walfisch, Asnat; Beharier, Ofer; Shoham-Vardi, Ilana; Sergienko, Ruslan; Landau, Daniella; Sheiner, Eyal

2016-08-01

The long-term impact of placenta previa on term infants is unknown. We aimed to investigate whether abnormal placentation increases the risk for long-term morbidity of the term offspring. A population-based cohort study compared the incidence of long-term hospitalizations up to the age of 18 due to cardiovascular, endocrine, neurological, hematological, respiratory and urinary morbidity of children born at term in pregnancies diagnosed with placenta previa and those without. Deliveries occurred between the years 1991-2013 in a tertiary medical center. Multiple pregnancies, and fetal congenital malformations were excluded. Kaplan-Meier survival curves were used to compare cumulative morbidity incidence over time. A multivariable generalized estimating equation (GEE) logistic regression model analysis was used to control for confounders and for maternal clusters. During the study period 233,123 term deliveries met the inclusion criteria; 0.2% (n=502) of the children were born to mothers with placenta previa. During the follow-up period, children born to mothers with placenta previa did not have an increased risk for long-term cardiovascular, endocrine, hematological, neurological, respiratory, and urinary morbidity. Term offsprings of mothers diagnosed with placenta previa do not appear to be at an increased risk for long-term morbidity up to the age of 18. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Long-Term Multiwavelength Observations of GRS 1758-258 and the Advection-dominated Accretion Flow Model

NASA Astrophysics Data System (ADS)

Keck, John W.; Craig, William W.; Hailey, Charles J.; Harrison, Fiona; Hong, Jae Sub; Kahn, Steven M.; Lubin, Philip M.; McLean, Ryan; Pivovaroff, Michael J.; Seiffert, Michael; Wurtz, Ron; Ziock, Klaus P.

2001-12-01

We present a long-term multiwavelength light curve of Galactic black hole candidate GRS 1758-258 by combining previously published and archival data from Granat, ROSAT, the Compton Gamma Ray Observatory, the Rossi X-Ray Timing Explorer, BeppoSAX, ASCA, EXOSAT, and the Very Large Array. In addition, we include the first spectral results from the balloon-borne Gamma-Ray Arcminute Telescope Imaging System (GRATIS). In light of divergent analyses of the 1991-1993 ROSAT observations, we have reanalyzed these data; we find that the soft X-rays track the hard X-rays and that the fits require no blackbody component-indicating that GRS 1758-258 did not go to the high state in 1993. We offer an interpretation of these long-baseline data based on the advection-dominated accretion flow (ADAF) model for a system with m<~mcrit. We find that the 1990-1993 coeval hard and soft X-ray observations support the ADAF predictions. We discuss a new way to constrain black hole mass with spectral data and the ADAF theory and apply this technique to GRS 1758-258 to find M1>~8-9 Msolar at an assumed distance of 8.5 kpc. Further investigations of the ADAF model allow us to evaluate the model critically against the 1996 data and flux-flux diagram of Barret, McClintock, & Grindlay and to understand the limits of the latter's ``X-ray burster box.''

Long-term data archiving

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moore, David Steven

2009-01-01

Long term data archiving has much value for chemists, not only to retain access to research and product development records, but also to enable new developments and new discoveries. There are some recent regulatory requirements (e.g., FDA 21 CFR Part 11), but good science and good business both benefit regardless. A particular example of the benefits of and need for long term data archiving is the management of data from spectroscopic laboratory instruments. The sheer amount of spectroscopic data is increasing at a scary rate, and the pressures to archive come from the expense to create the data (or recreatemore » it if it is lost) as well as its high information content. The goal of long-term data archiving is to save and organize instrument data files as well as any needed meta data (such as sample ID, LIMS information, operator, date, time, instrument conditions, sample type, excitation details, environmental parameters, etc.). This editorial explores the issues involved in long-term data archiving using the example of Raman spectral databases. There are at present several such databases, including common data format libraries and proprietary libraries. However, such databases and libraries should ultimately satisfy stringent criteria for long term data archiving, including readability for long times into the future, robustness to changes in computer hardware and operating systems, and use of public domain data formats. The latter criterion implies the data format should be platform independent and the tools to create the data format should be easily and publicly obtainable or developable. Several examples of attempts at spectral libraries exist, such as the ASTM ANDI format, and the JCAMP-DX format. On the other hand, proprietary library spectra can be exchanged and manipulated using proprietary tools. As the above examples have deficiencies according to the three long term data archiving criteria, Extensible Markup Language (XML; a product of the World Wide

Consider long-term care as service alternative.

PubMed

Loria, L S

1987-04-01

The increasing demand for elderly care services, pressures on inpatient average length of stay and payment levels, and potential financial rewards from providing additional services, makes long-term care look attractive to hospitals. Long-term care, however, is not for every hospital. Before deciding to establish long-term care services, management should examine how the service fits within the hospital's strategic plan. The action plan below provides guidance in evaluating a decision to use hospital facilities for long-term care. Examine how long-term care services fit within the hospital's strategic plan. Study area demographics and competitors to assess the need and supply of long-term care services. Survey the medical staff, consumers and payers to determine attitudes, perceptions and interests regarding long-term care services. Develop a facility plan that identifies areas of excess capacity that can be most easily converted into long-term care with minimal effects on hospital operations. Prepare a financial feasibility analysis of the contribution margin and return on investment attributable to long-term care services. Include an impact analysis on hospital operations. Establish a management task force to develop a detailed implementation plan including assigned individual responsibilities and related timetable. Develop an effective marketing plan designed to generate increased patient market share.

DACCIWA Cloud-Aerosol Observations in West Africa Field Campaign Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chiu, J Christine; Blanchard, Yann; Hill, Peter

Interactions between aerosols and clouds, and their effects on radiation, precipitation, and regional circulations, are one of the largest uncertainties in understanding climate. With reducing uncertainties in predictions of weather, climate, and climate impacts in mind, the Dynamics-Aerosol-Chemistry-Cloud Interactions in West Africa (DACCIWA) project, funded by the European Commission, set out to improve our understanding of cloud-aerosol interactions in southern West Africa. This region is ideal for studying cloud-aerosol interactions because of its rich mix of natural and anthropogenic aerosols and diverse clouds, and because of the strong dependence on the regional and global climate of the sensitive West Africanmore » monsoon. The overview of DACCIWA is described in Knippertz et al. 2015. The interdisciplinary DACCIWA team includes not only several European and African universities, but also Met Centres in the UK, France, Germany, Switzerland, Benin, Ghana, and Nigeria. One of the crucial research activities in DACCIWA is the major field campaign in southern West Africa from June to July 2016, comprising a benchmark data set for assessing detailed processes on natural and anthropogenic emissions; atmospheric composition; air pollution and its impacts on human and ecosystem health; boundary layer processes; couplings between aerosols, clouds, and rainfall; weather systems; radiation; and the monsoon circulation. Details and highlights of the campaign can be found in Flamant et al. 2017. To provide aerosol/cloud microphysical and optical properties that are essential for model evaluations and for the linkage between ground-based, airborne, and spaceborne observations, the U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Climate Research Facility loaned two sun photometers to the DACCWIA team for the campaign from June 8 to July 29, 2016. The first sun photometer was deployed at Kumasi, Ghana (6.67962°N, 1.56019°W) by the University of

Long-Term Changes in Stratospheric Age Spectra in the 21st Century in the Goddard Earth Observing System Chemistry-Climate Model (GEOSCCM)

NASA Technical Reports Server (NTRS)

Li, Feng; Waugh, Darryn W.; Douglass, Anne R.; Newman, Paul A.; Strahan, Susan E.; Ma, Jun; Nielsen, J. Eric; Liang, Qing

2012-01-01

In this study we investigate the long-term variations in the stratospheric age spectra using simulations of the 21st century with the Goddard Earth Observing System Chemistry- Climate Model (GEOSCCM). Our purposes are to characterize the long-term changes in the age spectra and identify processes that cause the decrease of the mean age in a warming climate. Changes in the age spectra in the 21st century simulations are characterized by decreases in the modal age, the mean age, the spectral width, and the tail decay timescale. Our analyses show that the decrease in the mean age is caused by two processes: the acceleration of the residual circulation that increases the young air masses in the stratosphere, and the weakening of the recirculation that leads to the decrease of tail of the age spectra and the decrease of the old air masses. The weakening of the stratospheric recirculation is also strongly correlated with the increase of the residual circulation. One important result of this study is that the decrease of the tail of the age spectra makes an important contribution to the decrease of the main age. Long-term changes in the stratospheric isentropic mixing are investigated. Mixing increases in the subtropical lower stratosphere, but its impact on the age spectra is outweighed by the increase of the residual circulation. The impacts of the long-term changes in the age spectra on long-lived chemical traces are also investigated. 37 2

Vitamin D status among long-term survivors of testicular cancer.

PubMed

Schepisi, Giuseppe; De Padova, Silvia; Scarpi, Emanuela; Lolli, Cristian; Gurioli, Giorgia; Menna, Cecilia; Burgio, Salvatore L; Rossi, Lorena; Gallà, Valentina; Casadio, Valentina; Salvi, Samanta; Conteduca, Vincenza; De Giorgi, Ugo

2017-05-30

A correlation between disturbances in hormone levels and the onset of metabolic disorders has been reported in long-term survivors of testicular cancer (TC).We evaluated serum vitamin D levels and other biological parameters in a consecutive series of 61 long-term (≥3 years) unilateral TC survivors with a median a follow-up of 4 years and in a cohort of healthy males. Deficient vitamin D levels were observed in 10 (17%) of the 58 long-term unilateral TC survivors but were not reported in healthy males (p=.019, Fisher test). Median vitamin D levels were 18.6 ug/L in 58 assessable TC survivors and 23.6 ug/L in 40 healthy males (p=.031). In univariate logistic regression analysis, TC diagnosis was associated with inadequate levels of vitamin D (p=.047). Vitamin D levels were lower when follow-up was > 10 years, albeit this difference was not statistically significant (p=.074). Long-term (especially > 10 years) TC survivors may have difficulty maintaining optimal vitamin D levels. Larger studies are needed to better characterize vitamin D status and possible correlations with premature hormonal aging reported in long-term TC survivors.

TeV γ-ray fluxes from the long campaigns on Mrk 421 as constraints on the emission of TeV-PeV neutrinos and UHECRs

NASA Astrophysics Data System (ADS)

Fraija, N.; Marinelli, A.

2015-10-01

Long TeV γ-ray campaigns have been carried out to study the spectrum, variability and duty cycle of the BL Lac object Markarian 421. These campaigns have given some evidence of the presence of protons in the jet: (i) Its spectral energy distribution which shows two main peaks; one at low energies (∼1 keV) and the other at high energies (hundreds of GeV), has been described by using synchrotron proton blazar model. (ii) The study of the variability at GeV γ-rays and X-rays has indicated no significant correlation. (iii) TeV γ-ray detections without activity in X-rays, called "orphan flares" have been observed in this object. Recently, The Telescope Array Collaboration reported the arrival of 72 ultra-high-energy cosmic rays with some of them possibly related to the direction of Markarian 421. The IceCube Collaboration reported the detection of 37 extraterrestrial neutrinos in the TeV-PeV energy range collected during three consecutive years. In particular, no neutrino track events were associated with this source. In this paper, we consider the proton-photon interactions to correlate the TeV γ-ray fluxes reported by long campaigns with the neutrino and ultra-high-energy cosmic ray observations around this blazar. Considering the results reported by The IceCube and Telescope Array Collaborations, we found that only from ∼25% to 70% of TeV fluxes described with a power law function with exponential cutoff can come from the proton-photon interactions.

Long-Term Control Medications for Lung Diseases

MedlinePlus

... Asthma Medications Long-Term Control Medications Long-Term Control Medications Make an Appointment Ask a Question Refer Patient Long-term control medications are taken daily to control and prevent ...

Critical neural networks with short- and long-term plasticity.

PubMed

Michiels van Kessenich, L; Luković, M; de Arcangelis, L; Herrmann, H J

2018-03-01

In recent years self organized critical neuronal models have provided insights regarding the origin of the experimentally observed avalanching behavior of neuronal systems. It has been shown that dynamical synapses, as a form of short-term plasticity, can cause critical neuronal dynamics. Whereas long-term plasticity, such as Hebbian or activity dependent plasticity, have a crucial role in shaping the network structure and endowing neural systems with learning abilities. In this work we provide a model which combines both plasticity mechanisms, acting on two different time scales. The measured avalanche statistics are compatible with experimental results for both the avalanche size and duration distribution with biologically observed percentages of inhibitory neurons. The time series of neuronal activity exhibits temporal bursts leading to 1/f decay in the power spectrum. The presence of long-term plasticity gives the system the ability to learn binary rules such as xor, providing the foundation of future research on more complicated tasks such as pattern recognition.

Critical neural networks with short- and long-term plasticity

NASA Astrophysics Data System (ADS)

Michiels van Kessenich, L.; Luković, M.; de Arcangelis, L.; Herrmann, H. J.

2018-03-01

In recent years self organized critical neuronal models have provided insights regarding the origin of the experimentally observed avalanching behavior of neuronal systems. It has been shown that dynamical synapses, as a form of short-term plasticity, can cause critical neuronal dynamics. Whereas long-term plasticity, such as Hebbian or activity dependent plasticity, have a crucial role in shaping the network structure and endowing neural systems with learning abilities. In this work we provide a model which combines both plasticity mechanisms, acting on two different time scales. The measured avalanche statistics are compatible with experimental results for both the avalanche size and duration distribution with biologically observed percentages of inhibitory neurons. The time series of neuronal activity exhibits temporal bursts leading to 1 /f decay in the power spectrum. The presence of long-term plasticity gives the system the ability to learn binary rules such as xor, providing the foundation of future research on more complicated tasks such as pattern recognition.

Independence of long-term contextual memory and short-term perceptual hypotheses: Evidence from contextual cueing of interrupted search.

PubMed

Schlagbauer, Bernhard; Mink, Maurice; Müller, Hermann J; Geyer, Thomas

2017-02-01

Observers are able to resume an interrupted search trial faster relative to responding to a new, unseen display. This finding of rapid resumption is attributed to short-term perceptual hypotheses generated on the current look and confirmed upon subsequent looks at the same display. It has been suggested that the contents of perceptual hypotheses are similar to those of other forms of memory acquired long-term through repeated exposure to the same search displays over the course of several trials, that is, the memory supporting "contextual cueing." In three experiments, we investigated the relationship between short-term perceptual hypotheses and long-term contextual memory. The results indicated that long-term, contextual memory of repeated displays neither affected the generation nor the confirmation of short-term perceptual hypotheses for these displays. Furthermore, the analysis of eye movements suggests that long-term memory provides an initial benefit in guiding attention to the target, whereas in subsequent looks guidance is entirely based on short-term perceptual hypotheses. Overall, the results reveal a picture of both long- and short-term memory contributing to reliable performance gains in interrupted search, while exerting their effects in an independent manner.

Reforming Long-Term Care Funding in Alberta.

PubMed

Crump, R Trafford; Repin, Nadya; Sutherland, Jason M

2015-01-01

Like many provinces across Canada, Alberta is facing growing demand for long-term care. Issues with the mixed funding model used to pay long-term care providers had Alberta Health Services concerned that it was not efficiently meeting the demand for long-term care. Consequently, in 2010, Alberta Health Services introduced the patient/care-based funding (PCBF) model. PCBF is similar to activity-based funding in that it directly ties the complexity and care needs of long-term care residents to the payment received by long-term care providers. This review describes PCBF and discusses some of its strengths and weaknesses. In doing so, this review is intended to inform other provinces faced with similar long-term care challenges and contemplating their own funding reforms.

Murine model of long term obstructive jaundice

PubMed Central

Aoki, Hiroaki; Aoki, Masayo; Yang, Jing; Katsuta, Eriko; Mukhopadhyay, Partha; Ramanathan, Rajesh; Woelfel, Ingrid A.; Wang, Xuan; Spiegel, Sarah; Zhou, Huiping; Takabe, Kazuaki

2016-01-01

Background With the recent emergence of conjugated bile acids as signaling molecules in cancer, a murine model of obstructive jaundice by cholestasis with long-term survival is in need. Here, we investigated the characteristics of 3 murine models of obstructive jaundice. Methods C57BL/6J mice were used for total ligation of the common bile duct (tCL), partial common bile duct ligation (pCL), and ligation of left and median hepatic bile duct with gallbladder removal (LMHL) models. Survival was assessed by Kaplan-Meier method. Fibrotic change was determined by Masson-Trichrome staining and Collagen expression. Results 70% (7/10) of tCL mice died by Day 7, whereas majority 67% (10/15) of pCL mice survived with loss of jaundice. 19% (3/16) of LMHL mice died; however, jaundice continued beyond Day 14, with survival of more than a month. Compensatory enlargement of the right lobe was observed in both pCL and LMHL models. The pCL model demonstrated acute inflammation due to obstructive jaundice 3 days after ligation but jaundice rapidly decreased by Day 7. The LHML group developed portal hypertension as well as severe fibrosis by Day 14 in addition to prolonged jaundice. Conclusion The standard tCL model is too unstable with high mortality for long-term studies. pCL may be an appropriate model for acute inflammation with obstructive jaundice but long term survivors are no longer jaundiced. The LHML model was identified to be the most feasible model to study the effect of long-term obstructive jaundice. PMID:27916350

Development of Download System for Waveform Data Observed at Long-Term Borehole Monitoring System installed in the Nankai Trough

NASA Astrophysics Data System (ADS)

Horikawa, H.; Takaesu, M.; Sueki, K.; Araki, E.; Sonoda, A.; Takahashi, N.; Tsuboi, S.

2015-12-01

The Nankai Trough in southwest Japan is one of most active subduction zone in the world. Great mega-thrust earthquakes repeatedly occurred every 100 to 150 years in this area, it's anticipated to occur in the not distant future. For the purpose of elucidation of the history of mega-splay fault activity, the physical properties of the geological strata and the internal structure of the accretionary prism, and monitoring of diastrophism in this area, we have a plan, Nankai Trough Seismogenic Zone Experiments (NanTroSEIZE), as a part of Integrated Ocean Drilling Program (IODP).We have a plan to install the borehole observation system in a few locations by the NanTroSEIZE. This system is called Long-Term Borehole Monitoring System, it consists of various sensors in the borehole such as a broadband seismometer, a tiltmeter, a strainmeter, geophones and accelerometer, thermometer array as well as pressure ports for pore-fluid pressure monitoring. The signal from sensors is transmitted to DONET (Dense Ocean-floor Network System for Earthquake and Tsunamis) in real-time. During IODP Exp. 332 in December 2010, the first Long-Term Borehole Monitoring System was installed into the C0002 borehole site located 80 km off the Kii Peninsula, 1938 m water depth in the Nankai Trough.We have developed a web application system for data download, Long-Term Borehole Monitoring Data Site　(*1). Based on a term and sensors which user selected on this site, user can download monitoring waveform data (e.g. broadband seismometer data, accelerometer data, strainmeter data, tiltmeter data) in near real-time. This system can make the arbitrary data which user selected a term and sensors, and download it simply. Downloadable continuous data is provided in seed format, which includes sensor information. In addition, before data download, user can check that data is available or not by data check function.In this presentation, we briefly introduce NanTroSEIZE and then show our web�

Use of Satellite Observations for Long-Term Exposure Assessment of Global Concentrations of Fine Particulate Matter

PubMed Central

Martin, Randall V.; Brauer, Michael; Boys, Brian L.

2014-01-01

Background: More than a decade of satellite observations offers global information about the trend and magnitude of human exposure to fine particulate matter (PM2.5). Objective: In this study, we developed improved global exposure estimates of ambient PM2.5 mass and trend using PM2.5 concentrations inferred from multiple satellite instruments. Methods: We combined three satellite-derived PM2.5 sources to produce global PM2.5 estimates at about 10 km × 10 km from 1998 through 2012. For each source, we related total column retrievals of aerosol optical depth to near-ground PM2.5 using the GEOS–Chem chemical transport model to represent local aerosol optical properties and vertical profiles. We collected 210 global ground-based PM2.5 observations from the literature to evaluate our satellite-based estimates with values measured in areas other than North America and Europe. Results: We estimated that global population-weighted ambient PM2.5 concentrations increased 0.55 μg/m3/year (95% CI: 0.43, 0.67) (2.1%/year; 95% CI: 1.6, 2.6) from 1998 through 2012. Increasing PM2.5 in some developing regions drove this global change, despite decreasing PM2.5 in some developed regions. The estimated proportion of the population of East Asia living above the World Health Organization (WHO) Interim Target-1 of 35 μg/m3 increased from 51% in 1998–2000 to 70% in 2010–2012. In contrast, the North American proportion above the WHO Air Quality Guideline of 10 μg/m3 fell from 62% in 1998–2000 to 19% in 2010–2012. We found significant agreement between satellite-derived estimates and ground-based measurements outside North America and Europe (r = 0.81; n = 210; slope = 0.68). The low bias in satellite-derived estimates suggests that true global concentrations could be even greater. Conclusions: Satellite observations provide insight into global long-term changes in ambient PM2.5 concentrations. Satellite-derived estimates and ground-based PM2.5 observations from this study

Long-term observations of seafloor pressure variations at Lucky Strike volcano, Mid-Atlantic Ridge

NASA Astrophysics Data System (ADS)

Ballu, V.; de Viron, O.; Crawford, W. C.; Cannat, M.; Escartin, J.

2012-12-01

Lucky Strike volcano is a segment-center volcano on the Mid-Atlantic Ridge at 37°N. Extensive faulting reveals an important tectonic component in its formation, while a seismically imaged axial magma chamber reflector and active high-temperature hydrothermal vents reveal an important present-day magmatic component. Lucky Strike volcano has been the subject of long-term multidisciplinary seafloor observations to understand relations between magmatism, tectonism, hydrothermal circulation, biology and chemistry as part of the MoMAR (Monitoring of the Mid-Atlantic Ridge) program. Absolute pressure gauges have been recording on the volcano since 2007, to identify deformations associated with tectonism or magmatism. Deformation measurements are one of the principal means of determining volcanic activity, but the amount of deformation associated with volcanic events varies greatly between different volcanos. We installed two sites: one in the volcano's summit "lava lake" (1700 m depth) and another on the volcano's flank (2000 m depth). Pressure is recorded every thirty seconds, giving a data set that constrains movements on the scale from minutes to years. No major deformation event has been detected by the instruments since their installation (nor has any significant tectonic event been detected by a seismic network in place since 2007), so we concentrate here on the detection limit of these instruments and on variations in the long-period ocean wave climate. Using the statistical characteristics of the pressure signal, modeled by an auto-regressive process, we determine that a movement between the sites of 1 cm over less than 10 days is detectable; the detection threshold decreases to about 0.2 cm for the shortest time periods and increases for longer time periods due to instrumental drift. We compare the statistical characteristics and short- and long-term sensitivity of three different types of gauges used during the experiment: Paroscientific standard

SBUV/2 Long-Term Measurements of Solar Spectral Variability

NASA Technical Reports Server (NTRS)

DeLand, Matthew T.; Cebula, Richard P.

1997-01-01

The NOAA-11 SBUV/2 spectral solar data have been corrected for long-term instrument changes to produce a 5.5 year data record during solar cycle 22 (December 1988 - October 1994). Residual drifts in the data at long wavelengths are +/- 1% or less. At 200-205 nm, where solar variations drive stratospheric photochemistry, these data indicate long-term solar changes of 5-7% from the maximum of Cycle 22 in April 1991 through the end of the NOAA-11 data record. Comparisons of NOAA-11 data with UARS SUSIM and SOLSTICE for the period October 1991 - October 1994, when all 3 instruments were operating simultaneously, show that the observed long-term variations in 200-205 nm irradiance agree to within 2%. This result is consistent with predictions from the Mg-2 proxy index. The SBUV/2 instruments represent a valuable resource for long-term solar UV activity studies because of their overlapping data records. In addition to the NOAA-11 data presented here, the NOAA-9 SBUV/2 instrument began taking data in March 1985 and is still operating, providing a complete record of Cycle 22 behavior from a single instrument. Three additional SBUV/2 instruments are scheduled to be launched between 1997 and 2003, which should permit full coverage of solar cycle 23.

Long-term observations of cloud condensation nuclei in the Amazon rain forest

NASA Astrophysics Data System (ADS)

Pöhlker, Mira L.; Pöhlker, Christopher; Ditas, Florian; Klimach, Thomas; Hrabe de Angelis, Isabella; Brito, Joel; Carbone, Samara; Cheng, Yafang; Martin, Scot T.; Moran-Zuloaga, Daniel; Rose, Diana; Saturno, Jorge; Su, Hang; Thalman, Ryan; Walter, David; Wang, Jian; Barbosa, Henrique; Artaxo, Paulo; Andreae, Meinrat O.; Pöschl, Ulrich

2017-04-01

Size-resolved long-term measurements of atmospheric aerosol and cloud condensation nuclei (CCN) concentrations and hygroscopicity were conducted at the remote Amazon Tall Tower Observatory (ATTO) in the central Amazon Basin over a full seasonal cycle (Mar 2014 - Feb 2015). The measurements provide a climatology of CCN properties characteristic of a remote central Amazonian rain forest site [1,2]. The CCN measurements were continuously cycled through 10 levels of supersaturation (S = 0.11 to 1.10 %) and span the aerosol particle size range from 20 to 245 nm. The particle hygroscopicity exhibits a pronounced size dependence with lower values for the Aitken mode (κAit = 0.14 ± 0.03), higher values for the accumulation mode (κAcc = 0.22 ± 0.05), and an overall mean value of κmean = 0.17 ± 0.06, consistent with high fractions of organic aerosol. The hygroscopicity parameter, κ, exhibits remarkably little temporal variability: no pronounced diurnal cycles, only weak seasonal trends, and few short-term variations during long-range transport events. In contrast, the CCN number concentrations exhibit a pronounced seasonal cycle, tracking the pollution-related seasonality in total aerosol concentration. We find that the variability in the CCN concentrations in the central Amazon is mostly driven by aerosol particle number concentration and size distribution, while variations in aerosol hygroscopicity and chemical composition matter only during a few episodes. For modelling purposes, we compare different approaches of predicting CCN number concentration and present a novel parameterization, which allows accurate CCN predictions based on a small set of input data. In addition, we analyzed the CCN short-term variability in relation to air mass changes as well as aerosol emission and transformation processes. The CCN short term variability is presented for selected case studies, which analyze particularly interesting and characteristic events/conditions in the Amazon

GLOBE Aerosol Field Campaign - U.S. Pilot Study 2016

NASA Technical Reports Server (NTRS)

Pippin, Margaret; Marentette, Christina; Bujosa, Robert; Taylor, Jessica; Lewis, Preston

2016-01-01

During the spring of 2016, from April 4 - May 27, sixteen GLOBE schools participated in the GLOBE Aerosol Field Campaign - U.S. Pilot Study. Thirteen teachers from these schools had previously participated in the NASA LEARN program (Long-term Experience in Authentic Research with NASA) where they were GLOBE trained in Atmosphere protocols, and engaged in 1-3 years of research under the mentorship of NASA scientists. Each school was loaned two aerosol instruments for the Campaign duration, either 2 GLOBE sun photometers, 2 Calitoo sun photometers, or 1 of each. This allowed for students to make measurements side-by-side and in the case of the Calitoos, to compare AOT results immediately with each other for better consistency in data collection. Additionally, as part of the Field Campaign evaluation, multiple instruments allow for an assessment of the ease of use of each instrument for grade level of students, whether in middle school or high school. Before the Campaign, all GLOBE and Calitoo instruments were 'checked out' against an AERONET, then checked again upon return after the Campaign. By examining all data, before, during and after the Campaign, this gives an indication of instrument performance and proficiency obtained by the students. Support was provided to each teacher and their students at the level requested, via email, phone or video conferencing.

Long-term stellar variability

NASA Astrophysics Data System (ADS)

Pagano, Isabella

2010-02-01

Stars with significant subsurface convection zones develop magnetic loop structures that, arising from the surface upward to the external atmospheres, cause flux variability detectable throughout the whole electromagnetic spectrum. In fact, diagnostics of magnetic activity are in radio wavelengths, where gyrosincrotron radiation arises from the quiescent and flaring corona; in the optical region, where important signatures are the Balmer lines, the Ca ii IRT and H&K lines; in the UV and X ray domains, the latter mainly due to coronal thermal plasma. The zoo of different magnetic features observed for the Sun - spots, faculae, flares, CMEs - are characterized by different temporal evolution and energetics, both in quantity and quality. As a consequence, the time scale of variability, the amount of involved energy and the quality of the involved photons are used as fingerprints in interpreting the observed stellar variability in the framework of the solar-stellar analogy. Here I review main results from long-term multiwavelength observations of cool star atmospheres, with emphasis to similarities and differences with the solar case.

Opportunities for in-depth compositional studies of comets: Summary from semester 2017A observations and prospects for a 2018 observing campaign

NASA Astrophysics Data System (ADS)

DiSanti, Michael A.; Dello Russo, Neil; Bonev, Boncho P.; Gibb, Erika L.; Roth, Nathan; Vervack, Ronald J.; McKay, Adam J.; Kawakita, Hideyo; Cochran, Anita L.

2017-10-01

The period from late 2016 to mid 2017 provided unusually rich observational opportunities for compositional studies of comets using ground-based IR and optical spectroscopy. Three ecliptic comets - Jupiter-family comet (JFC) 45P/Honda-Mrkos-Pajdusakova, JFC 41P/Tuttle-Giacobini-Kresak, and 2P/Encke - as well as two moderately bright nearly istotropic comets from the Oort cloud (C/2015 ER61 PanSTARRS and C/2015 V2 Johnson) experienced highly favorable appritions.In the IR, very long on-source integration times were accumulated on all targets, primarily with the powerful new high-resolution, cross-dispersed iSHELL spectrograph at the IRTF (Rayner et al. 2016 SPIE 9908:1) but also with NIRSPEC at Keck II. This enabled accurate production rates and abundance ratios for 8-10 native ices, and spatially resolved studies of coma physics (H2O rotational temperatures and column abundances). The recent availability of iSHELL coupled with the daytime observing capability at the IRTF has opened a powerful window for conducting detailed compositional studies of comets over a range of heliocentric distances (Rh), particularly at small Rh where studies are relatively sparse. Our campaign provided detections of (or stringent abundance limits for) hyper-volatiles CO and CH4, which are severely lacking in compositional studies of JFCs.For all of these targets, optical spectra measured photo-dissociation product species using the Tull Coude spectrograph at McDonald Observatory, and ARCES at Apache Point Observatory. When possible optical and IR observations were obtained contemporaneously, with the goal of addressing potential parent-product relationships.We summarize our campaign and highlight related presentations. Prospects for investigations during the upcoming favorable apparitions of JFCs 21P/Giacobini-Zinner and 46P/Wirtanen will also be discussed, along with increased capabilities for serial studies (i.e., measurements at multiple Rh) of newly discovered (Oort cloud) comets

Conceptual Distinctiveness Supports Detailed Visual Long-Term Memory for Real-World Objects

ERIC Educational Resources Information Center

Konkle, Talia; Brady, Timothy F.; Alvarez, George A.; Oliva, Aude

2010-01-01

Humans have a massive capacity to store detailed information in visual long-term memory. The present studies explored the fidelity of these visual long-term memory representations and examined how conceptual and perceptual features of object categories support this capacity. Observers viewed 2,800 object images with a different number of exemplars…

Ground-based ELF/VLF chorus observations at subauroral latitudes—VLF-CHAIN Campaign

NASA Astrophysics Data System (ADS)

Shiokawa, Kazuo; Yokoyama, Yu; Ieda, Akimasa; Miyoshi, Yoshizumi; Nomura, Reiko; Lee, Sungeun; Sunagawa, Naoki; Miyashita, Yukinaga; Ozaki, Mitsunori; Ishizaka, Kazumasa; Yagitani, Satoshi; Kataoka, Ryuho; Tsuchiya, Fuminori; Schofield, Ian; Connors, Martin

2014-09-01

We report observations of very low frequency (VLF) and extremely low frequency (ELF) chorus waves taken during the ELF/VLF Campaign observation with High-resolution Aurora Imaging Network (VLF-CHAIN) of 17-25 February 2012 at subauroral latitudes at Athabasca (L=4.3), Canada. ELF/VLF waves were measured continuously with a sampling rate of 100 kHz to monitor daily variations in ELF/VLF emissions and derive their detailed structures. We found quasiperiodic (QP) emissions whose repetition period changes rapidly within a period of 1 h without corresponding magnetic pulsations. QP emissions showed positive correlation between amplitude and frequency sweep rate, similarly to rising-tone elements. We found an event of nearly simultaneous enhancements of QP emissions and Pc1/electromagnetic ion cyclotron wave intensities, suggesting that the temperature anisotropy of electrons and ions developed simultaneously at the equatorial plane of the magnetosphere. We also found QP emissions whose intensity suddenly increased in association with storm sudden commencement without changing their frequency. Falling-tone ELF/VLF emissions were observed with their rate of frequency change varying from 0.7 to 0.05 kHz/s over 10 min. Bursty-patch emissions in the lower and upper frequency bands are often observed during magnetically disturbed periods. Clear systematic correlation between these various ELF/VLF emissions and cosmic noise absorption was not obtained throughout the campaign period. These observations indicate several previously unknown features of ELF/VLF emissions in subauroral latitudes and demonstrate the importance of continuous measurements for monitoring temporal variations in these emissions.

Cognitive correlates of long-term cannabis use in Costa Rican men.

PubMed

Fletcher, J M; Page, J B; Francis, D J; Copeland, K; Naus, M J; Davis, C M; Morris, R; Krauskopf, D; Satz, P

1996-11-01

Cognitive correlates of long-term cannabis use have been elusive. We tested the hypothesis that long-term cannabis use is associated with deficits in short term memory, working memory, and attention in a literate, westernized culture (Costa Rica) in which the effects of cannabis use can be isolated. Two cohorts of long-term cannabis users and nonusers were studied. Within each cohort, users and nonusers were comparable in age and socioeconomic status. Polydrug users and users who tested positive for the use of cannabis at the time of cognitive assessment after a 72-hour abstention period were excluded. The older cohort (whose age was approximately 45 years) had consumed cannabis for an average of 34 years, and comprised 17 users and 30 nonusers, who had been recruited in San José, Costa Rica, and had been observed since 1973. The younger cohort (whose age was approximately 28 years) had consumed cannabis for an average of 8 years, and comprised 37 users and 49 nonusers. Short-term memory, working memory, and attentional skills were measured in each subject. Older long-term users performed worse than older nonusers on 2 short-term memory tests involving learning lists of words. In addition, older long-term users performed worse than older nonusers on selective and divided attention tasks associated with working memory. No notable differences were apparent between younger users and nonusers. Long-term cannabis use was associated with disruption of short-term memory, working memory, and attentional skills in older long-term cannabis users.

Tropospheric ozone long term trend observed by lidar and ECC ozonesondes at Observatoire de Haute Provence, Southern France.

NASA Astrophysics Data System (ADS)

Ancellet, G.; Gaudel, A.; Godin-Beekmann, S.

2016-12-01

Tropospheric ozone vertical profile measurements have been carried out at OHP (Observatoire de Haute Provence, 44°N, 6.7°E, 690 m) since 1991 using both UV DIAL (DIfferential Absorption Lidar) and ECC (Electrochemical Concentration Cell) ozonesondes. For the first time, ECC and lidar data measured at the same site, have been compared over a 24 year period. The comparison conducted reveals a bias between both measurement types (ECC - lidar) of the order of 0.6 ppbv. The measurements of both instruments have been however combined to decrease the impact of short-term atmospheric variability on the trend estimate. Air mass trajectories have been calculated for all the ozone observations available at OHP including ECMWF potential vorticity (PV) and humidity chnage along the trajectories. The interannual ozone variability shows a negligible trend in the mid troposphere, but a 0.36 ppbv/year significant positive ozone trend in the upper troposphere. The trends will be discussed using the variability of the meteorological parameters. Data clustering using PV and air mass trajectories is useful to identify the role of Stratosphere-Tropopshere Exchanges and long range transport of pollutants in the observed long term trends. In the lower troposphere, the interannual variability shows contrasted trends with an ozone decrease between 1998 and 2008, consistent with the NOx emission decrease, but a new period of ozone increase since 2008 which is not very well understood.

Observing Strategies for the Detection of Jupiter Analogs

NASA Astrophysics Data System (ADS)

Wittenmyer, Robert A.; Tinney, C. G.; Horner, J.; Butler, R. P.; Jones, H. R. A.; O'Toole, S. J.; Bailey, J.; Carter, B. D.; Salter, G. S.; Wright, D.

2013-04-01

To understand the frequency, and thus the formation and evolution, of planetary systems like our own solar system, it is critical to detect Jupiter-like planets in Jupiter-like orbits. For long-term radial-velocity monitoring, it is useful to estimate the observational effort required to reliably detect such objects, particularly in light of severe competition for limited telescope time. We perform detailed simulations of observational campaigns, maximizing the realism of the sampling of a set of simulated observations. We then compute the detection limits for each campaign to quantify the effect of increasing the number of observational epochs and varying their time coverage. We show that once there is sufficient time baseline to detect a given orbital period, it becomes less effective to add further time coverage—rather, the detectability of a planet scales roughly as the square root of the number of observations, independently of the number of orbital cycles included in the data string. We also show that no noise floor is reached, with a continuing improvement in detectability at the maximum number of observations N = 500 tested here.

Long-term effects of interference on short-term memory performance in the rat.

PubMed

Missaire, Mégane; Fraize, Nicolas; Joseph, Mickaël Antoine; Hamieh, Al Mahdy; Parmentier, Régis; Marighetto, Aline; Salin, Paul Antoine; Malleret, Gaël

2017-01-01

A distinction has always been made between long-term and short-term memory (also now called working memory, WM). The obvious difference between these two kinds of memory concerns the duration of information storage: information is supposedly transiently stored in WM while it is considered durably consolidated into long-term memory. It is well acknowledged that the content of WM is erased and reset after a short time, to prevent irrelevant information from proactively interfering with newly stored information. In the present study, we used typical WM radial maze tasks to question the brief lifespan of spatial WM content in rodents. Groups of rats were submitted to one of two different WM tasks in a radial maze: a WM task involving the repetitive presentation of a same pair of arms expected to induce a high level of proactive interference (PI) (HIWM task), or a task using a different pair in each trial expected to induce a low level of PI (LIWM task). Performance was effectively lower in the HIWM group than in LIWM in the final trial of each training session, indicative of a "within-session/short-term" PI effect. However, we also observed a different "between-session/long-term" PI effect between the two groups: while performance of LIWM trained rats remained stable over days, the performance of HIWM rats dropped after 10 days of training, and this impairment was visible from the very first trial of the day, hence not attributable to within-session PI. We also showed that a 24 hour-gap across training sessions known to allow consolidation processes to unfold, was a necessary and sufficient condition for the long-term PI effect to occur. These findings suggest that in the HIWM task, WM content was not entirely reset between training sessions and that, in specific conditions, WM content can outlast its purpose by being stored more permanently, generating a long-term deleterious effect of PI. The alternative explanation is that WM content could be transferred and stored

Long-term repetition priming with symmetrical polygons and words.

PubMed

Kersteen-Tucker, Z

1991-01-01

In two different tasks, subjects were asked to make lexical decisions (word or nonword) and symmetry judgments (symmetrical or nonsymmetrical) about two-dimensional polygons. In both tasks, every stimulus was repeated at one of four lags (0, 1, 4, or 8 items interposed between the first and second stimulus presentations). This paradigm, known as repetition priming, revealed comparable short-term priming (Lag 0) and long-term priming (Lags 1, 4, and 8) both for symmetrical polygons and for words. A shorter term component (Lags 0 and 1) of priming was observed for nonwords, and only very short-term priming (Lag 0) was observed for nonsymmetrical polygons. These results indicate that response facilitation accruing from repeated exposure can be observed for stimuli that have no preexisting memory representations and suggest that perceptual factors contribute to repetition-priming effects.

Determinants of success and sustainability of the WHO multimodal hand hygiene promotion campaign, Italy, 2007-2008 and 2014.

PubMed

Moro, Maria Luisa; Morsillo, Filomena; Nascetti, Simona; Parenti, Mita; Allegranzi, Benedetta; Pompa, Maria Grazia; Pittet, Didier

2017-06-08

A national hand hygiene promotion campaign based on the World Health Organization (WHO) multimodal, Clean Care is Safer Care campaign was launched in Italy in 2007. One hundred seventy-five hospitals from 14 of 20 Italian regions participated. Data were collected using methods and tools provided by the WHO campaign, translated into Italian. Hand hygiene compliance, ward infrastructure, and healthcare workers' knowledge and perception of healthcare-associated infections and hand hygiene were evaluated before and after campaign implementation. Compliance data from the 65 hospitals returning complete data for all implementation tools were analysed using a multilevel approach. Overall, hand hygiene compliance increased in the 65 hospitals from 40% to 63% (absolute increase: 23%, 95% confidence interval: 22-24%). A wide variation in hand hygiene compliance among wards was observed; inter-ward variability significantly decreased after campaign implementation and the level of perception was the only item associated with this. Long-term sustainability in 48 of these 65 hospitals was assessed in 2014 using the WHO Hand Hygiene Self-Assessment Framework tool. Of the 48 hospitals, 44 scored in the advanced/intermediate categories of hand hygiene implementation progress. The median hand hygiene compliance achieved at the end of the 2007-2008 campaign appeared to be sustained in 2014. This article is copyright of The Authors, 2017.

Short-term and long-term effects of violent media on aggression in children and adults.

PubMed

Bushman, Brad J; Huesmann, L Rowell

2006-04-01

To test whether the results of the accumulated studies on media violence and aggressive behavior are consistent with the theories that have evolved to explain the effects. We tested for the existence of both short-term and long-term effects for aggressive behavior. We also tested the theory-driven hypothesis that short-term effects should be greater for adults and long-term effects should be greater for children. Meta-analysis. Children younger than 18 years and adults. Violent media, including TV, movies, video games, music, and comic books. Measures of aggressive behavior, aggressive thoughts, angry feelings, physiological arousal (eg, heart rate, blood pressure), and helping behavior. Effect size estimates were combined using meta-analytic procedures. As expected, the short-term effects of violent media were greater for adults than for children whereas the long-term effects were greater for children than for adults. The results also showed that there were overall modest but significant effect sizes for exposure to media violence on aggressive behaviors, aggressive thoughts, angry feelings, arousal levels, and helping behavior. The results are consistent with the theory that short-term effects are mostly due to the priming of existing well-encoded scripts, schemas, or beliefs, which adults have had more time to encode. In contrast, long-term effects require the learning (encoding) of scripts, schemas, or beliefs. Children can encode new scripts, schemas, and beliefs via observational learning with less interference and effort than adults.

A phenomenological memristor model for short-term/long-term memory

NASA Astrophysics Data System (ADS)

Chen, Ling; Li, Chuandong; Huang, Tingwen; Ahmad, Hafiz Gulfam; Chen, Yiran

2014-08-01

Memristor is considered to be a natural electrical synapse because of its distinct memory property and nanoscale. In recent years, more and more similar behaviors are observed between memristors and biological synapse, e.g., short-term memory (STM) and long-term memory (LTM). The traditional mathematical models are unable to capture the new emerging behaviors. In this article, an updated phenomenological model based on the model of the Hewlett-Packard (HP) Labs has been proposed to capture such new behaviors. The new dynamical memristor model with an improved ion diffusion term can emulate the synapse behavior with forgetting effect, and exhibit the transformation between the STM and the LTM. Further, this model can be used in building new type of neural networks with forgetting ability like biological systems, and it is verified by our experiment with Hopfield neural network.

The Long-Term Budget Outlook

DTIC Science & Technology

2005-12-01

Revenues Under CBO’s Long-Term Budget Scenarios 56A-8. Real Gross Domestic Product Under CBO’s Long-Term Budget Scenarios 57A-9. Total Surplus or...scenarios suggest that total federal spending for Medicare and Medicaid in 2050 could range anywhere from 7 percent of gross domestic product (GDP)—a...see the Congressional Budget Office’s glossary of budgetary and economic terms, available at www.cbo.gov. 2. The future path of productivity growth

Comparison of two humidification systems for long-term noninvasive mechanical ventilation.

PubMed

Nava, S; Cirio, S; Fanfulla, F; Carlucci, A; Navarra, A; Negri, A; Ceriana, P

2008-08-01

There is no consensus concerning the best system of humidification during long-term noninvasive mechanical ventilation (NIMV). In a technical pilot randomised crossover 12-month study, 16 patients with stable chronic hypercapnic respiratory failure received either heated humidification or heat and moisture exchanger. Compliance with long-term NIMV, airway symptoms, side-effects and number of severe acute pulmonary exacerbations requiring hospitalisation were recorded. Two patients died. Intention-to-treat statistical analysis was performed on 14 patients. No significant differences were observed in compliance with long-term NIMV, but 10 out of 14 patients decided to continue long-term NIMV with heated humidification at the end of the trial. The incidence of side-effects, except for dry throat (significantly more often present using heat and moisture exchanger), hospitalisations and pneumonia were not significantly different. In the present pilot study, the use heated humidification and heat and moisture exchanger showed similar tolerance and side-effects, but a higher number of patients decided to continue long-term noninvasive mechanical ventilation with heated humidification. Further larger studies are required in order to confirm these findings.

Campaign datasets for Biomass Burning Observation Project (BBOP)

DOE Data Explorer

Kleinman,Larry; Mei,Fan; Arnott,William; Buseck,Peter; Chand,Duli; Comstock,Jennifer; Dubey,Manvendra; Lawson,Paul; Long,Chuck; Onasch,Timothy; Sedlacek,Arthur; Senum,Gunnar; Shilling,John; Springston,Stephen; Tomlinson,Jason; Wang,Jian

2014-04-24

This field campaign will address multiple uncertainties in aerosol intensive properties, which are poorly represented in climate models, by means of aircraft measurements in biomass burning plumes. Key topics to be investigated are: 1. Aerosol mixing state and morphology 2. Mass absorption coefficients (MACs) 3. Chemical composition of non-refractory material associated with light-absorbing carbon (LAC) 4. Production rate of secondary organic aerosol (SOA) 5. Microphysical processes relevant to determining aerosol size distributions and single scattering albedo (SSA) 6. CCN activity. These topics will be investigated through measurements near active fires (0-5 hours downwind), where limited observations indicate rapid changes in aerosol properties, and in biomass burning plumes aged >5 hours. Aerosol properties and their time evolution will be determined as a function of fire type, defined according to fuel and the mix of flaming and smoldering combustion at the source.

Long-Term Observation of Small and Medium-Scale Gravity Waves over the Brazilian Equatorial Region

NASA Astrophysics Data System (ADS)

Essien, Patrick; Buriti, Ricardo; Wrasse, Cristiano M.; Medeiros, Amauri; Paulino, Igo; Takahashi, Hisao; Campos, Jose Andre

2016-07-01

This paper reports the long term observations of small and medium-scale gravity waves over Brazilian equatorial region. Coordinated optical and radio measurements were made from OLAP at Sao Joao do Cariri (7.400S, 36.500W) to investigate the occurrences and properties and to characterize the regional mesospheric gravity wave field. All-sky imager measurements were made from the site. for almost 11 consecutive years (September 2000 to November 2010). Most of the waves propagated were characterized as small-scale gravity. The characteristics of the two waves events agreed well with previous gravity wave studies from Brazil and other sites. However, significant differences in the wave propagation headings indicate dissimilar source regions. The observed medium-scale gravity wave events constitute an important new dataset to study their mesospheric properties at equatorial latitudes. These data exhibited similar propagation headings to the short period events, suggesting they originated from the same source regions. It was also observed that some of the medium-scale were capable of propagating into the lower thermosphere where they may have acted directly as seeds for the Rayleigh-Taylor instability development. The wave events were primarily generated by meteorological processes since there was no correlation between the evolution of the wave events and solar cycle F10.7.

Trends in Streamflow Characteristics at Long-Term Gaging Stations, Hawaii

USGS Publications Warehouse

Oki, Delwyn S.

2004-01-01

The surface-water resources of Hawaii have significant cultural, aesthetic, ecologic, and economic importance. Proper management of the surface-water resources of the State requires an understanding of the long- and short-term variability in streamflow characteristics that may occur. The U.S. Geological Survey maintains a network of stream-gaging stations in Hawaii, including a number of stations with long-term streamflow records that can be used to evaluate long-term trends and short-term variability in flow characteristics. The overall objective of this study is to obtain a better understanding of long-term trends and variations in streamflow on the islands of Hawaii, Maui, Molokai, Oahu, and Kauai, where long-term stream-gaging stations exist. This study includes (1) an analysis of long-term trends in flows (both total flow and estimated base flow) at 16 stream-gaging stations, (2) a description of patterns in trends within the State, and (3) discussion of possible regional factors (including rainfall) that are related to the observed trends and variations. Results of this study indicate the following: 1. From 1913 to 2002 base flows generally decreased in streams for which data are available, and this trend is consistent with the long-term downward trend in annual rainfall over much of the State during that period. 2. Monthly mean base flows generally were above the long-term average from 1913 to the early 1940s and below average after the early 1940s to 2002, and this pattern is consistent with the detected downward trends in base flows from 1913 to 2002. 3. Long-term downward trends in base flows of streams may indicate a reduction in ground-water discharge to streams caused by a long-term decrease in ground-water storage and recharge. 4. From 1973 to 2002, trends in streamflow were spatially variable (up in some streams and down in others) and, with a few exceptions, generally were not statistically significant. 5. Short-term variability in streamflow is

Long-term seismic observations along Myanmar-Sunda subduction margin: insights for 2004 M w > 9.0 earthquake

NASA Astrophysics Data System (ADS)

Khan, Prosanta Kumar; Banerjee, Jayashree; Shamim, Sk; Mohanty, Manoranjan

2018-03-01

The present study investigates the temporal variation of few seismic parameters between the Myanmar (Zone I), Andaman-Nicobar-Northwest Sumatra (Zone II), Southeast Sumatra-West Indonesia (Zone III) and East Indonesia (Zone IV) converging boundaries in reference to the generation of 26 December 2004 M w > 9.0 off-Sumatra mega-earthquake event. The four segments are distinguished based on tectonics parameters, distinct geological locations, great earthquake occurrences, and the Wadati-Benioff zone characteristics. Two important seismic parameters such as seismic energy and b values are computed over a time-window of 6-month period during the entire 1976-2013 period for these segments. The b values show a constant decrease in Zones II, III, and IV, whereas the Zone I does not show any such pattern prior to the 2004 mega-event. The release of seismic energy was also gradually decreasing in Zones II and III till the 2004 event, and little similar pattern was also noted in Zone IV. This distinct observation might be indicating that the stress accumulation was dominant near the Sumatra-Java area located towards southeast of Zone II and northwest of Zone III. The released strain energy during the 2004 event was subsequently migrated towards north, rupturing 1300 km of the boundary between the Northwest Sumatra and the North Andaman. The occurrence of 2004 mega-event was apparently concealed behind the long-term seismic quiescence existing near the Sumatra and Nicobar margin. A systematic study of the patterns of seismic energy release and b values, and the long-term observation of collective behaviour of the margin tectonics might have had given clues to the possibility of the 2004 mega-event.

Long-term Accretion Variations of the Magnetic Cataclysmic Variable Star QQ Vulpecula

NASA Astrophysics Data System (ADS)

Cooper Rose, Sanaea; Kafka, Stella; Jorgenson, Regina; Carr, Derrick; Childs, Francesca; Christenson, Holly; Karim, Md. Tanveer; Konchady, Tarini; Walker, Gary E.; Honeycutt, R. K.

2017-01-01

Magnetic cataclysmic variable stars have brightness variations that repeat with each revolution of the two stars about the center of mass of the system. However, in the case of QQ Vulpecula (QQ Vul), this brightness variation pattern changes in the long term. This study makes use of two decades worth of data from the Roboscope Telescope as well as data from the American Association of Variable Star Observers (AAVSO) database to examine the long-term evolution of QQ Vul’s phase curves. Nightly observations using the Maria Mitchell Association's Vestal and Loines Observatories supplemented this analysis by clarifying short-term brightness variation. The long-term data was divided into four commonly observed behavioral types ranging from a double peaked curve of ~15.5 magnitude to a ~15.0 magnitude curve that had a primary minimum and a slow, linear rise in brightness in place of the secondary minimum. The nightly data kept within the confines of these categories, though the secondary minimum in the nightly data never vanished. No periodicity was found in the long-term variations. The model often invoked to explain the double peaked curve consists of single pole accretion in which a partial self-eclipse causes the secondary minimum and cyclotron beaming causes the primary minimum. However, the long-term variation may indicate a changing accretion rate, which may manifest itself in changes to the shape, size, or location of the accretion spot on the white dwarf such that it lessens or removes the secondary minimum. This project was supported by the NSF REU grant AST-1358980, the Massachusetts Space Grant, and the Nantucket Maria Mitchell Association.

Observational evidence of a long-term increase in precipitation due to urbanization effects and its implications for sustainable urban living.

PubMed

Wai, K M; Wang, X M; Lin, T H; Wong, M S; Zeng, S K; He, N; Ng, E; Lau, K; Wang, D H

2017-12-01

Although projected precipitation increases in East Asia due to future climate change have aroused concern, less attention has been paid by the scientific community and public to the potential long-term increase in precipitation due to rapid urbanization. A ten-year precipitation dataset was analysed for both a rapidly urbanized megacity and nearby suburban/rural stations in southern China. Rapid urbanization in the megacity was evident from satellite observations. A statistically significant, long-term, increasing trend of precipitation existed only at the megacity station (45.6mm per decade) and not at the other stations. The increase was attributed to thermal and dynamical modifications of the tropospheric boundary layer related to urbanization, which was confirmed by the results of our WRF-SLUCM simulations. The results also suggested that a long-term regional increase in precipitation, caused by greenhouse gas-induced climate change, for instance, was not evident within the study period. The urbanization-induced increase was found to be higher than the precipitation increase (18.3mm per decade) expected from future climate change. The direct climate impacts due to rapid urbanization is highlighted with strong implications for urban sustainable development and the planning of effective adaptation strategies for issues such as coastal defenses, mosquito-borne disease spread and heat stress mortality. Copyright © 2017 Elsevier B.V. All rights reserved.

Short-term Action Intentions Overrule Long-Term Semantic Knowledge

ERIC Educational Resources Information Center

van Elk, M.; van Schie, H.T.; Bekkering, H.

2009-01-01

In the present study, we investigated whether the preparation of an unusual action with an object (e.g. bringing a cup towards the eye) could selectively overrule long-term semantic representations. In the first experiment it was found that unusual action intentions activated short-term semantic goal representations, rather than long-term…

Drug-nutrient interactions in three long-term-care facilities.

PubMed

Lewis, C W; Frongillo, E A; Roe, D A

1995-03-01

To assess the risk of drug-nutrient interactions (DNIs) in three long-term-care facilities. Retrospective audit of charts. Three long-term-care facilities in central New York State. Fifty-three patients selected randomly from each facility. Data were collected from the medical record of each patient for a period of 6 months. A computerized algorithm was used to assess the risk for DNIs. Mean drug use, most frequently consumed drugs, incidence of potential DNIs, and the most commonly observed potential DNIs are reported. In facilities A, B, and C, respectively, patients consumed a mean of 4.86, 4.04, and 5.27 drugs per patient per month and were at risk for a mean of 1.43, 2.69, and 1.43 potential DNIs per patient per month. The most commonly observed potential DNIs were gastrointestinal interactions affecting drug bioavailability and interactions affecting electrolyte status. Patients in long-term-care facilities, who are primarily elderly and chronically ill and who consume multiple medications, are at notable risk for certain DNIs. Efforts need to be made to ensure appropriate pharmacologic and nutrition therapies as well as adequate and timely monitoring of patients in these facilities. Dietitians can play an important role in training other health professionals and in designing policies to prevent DNIs.

A role for autophagy in long-term spatial memory formation in male rodents.

PubMed

Hylin, Michael J; Zhao, Jing; Tangavelou, Karthikeyan; Rozas, Natalia S; Hood, Kimberly N; MacGowan, Jacalyn S; Moore, Anthony N; Dash, Pramod K

2018-03-01

A hallmark of long-term memory formation is the requirement for protein synthesis. Administration of protein synthesis inhibitors impairs long-term memory formation without influencing short-term memory. Rapamycin is a specific inhibitor of target of rapamycin complex 1 (TORC1) that has been shown to block protein synthesis and impair long-term memory. In addition to regulating protein synthesis, TORC1 also phosphorylates Unc-51-like autophagy activating kinase-1 (Ulk-1) to suppress autophagy. As autophagy can be activated by rapamycin (and rapamycin inhibits long-term memory), our aim was to test the hypothesis that autophagy inhibitors would enhance long-term memory. To examine if learning alters autophagosome number, we used male reporter mice carrying the GFP-LC3 transgene. Using these mice, we observed that training in the Morris water maze task increases the number of autophagosomes, a finding contrary to our expectations. For learning and memory studies, male Long Evans rats were used due to their relatively larger size (compared to mice), making it easier to perform intrahippocampal infusions in awake, moving animals. When the autophagy inhibitors 3-methyladenine (3-MA) or Spautin-1 were administered bilaterally into the hippocampii prior to training in the Morris water maze task, the drugs did not alter learning. In contrast, when memory was tested 24 hours later by a probe trial, significant impairments were observed. In addition, intrahippocampal infusion of an autophagy activator peptide (TAT-Beclin-1) improved long-term memory. These results indicate that autophagy is not necessary for learning, but is required for long-term memory formation. © 2017 Wiley Periodicals, Inc.

Murine model of long-term obstructive jaundice.

PubMed

Aoki, Hiroaki; Aoki, Masayo; Yang, Jing; Katsuta, Eriko; Mukhopadhyay, Partha; Ramanathan, Rajesh; Woelfel, Ingrid A; Wang, Xuan; Spiegel, Sarah; Zhou, Huiping; Takabe, Kazuaki

2016-11-01

With the recent emergence of conjugated bile acids as signaling molecules in cancer, a murine model of obstructive jaundice by cholestasis with long-term survival is in need. Here, we investigated the characteristics of three murine models of obstructive jaundice. C57BL/6J mice were used for total ligation of the common bile duct (tCL), partial common bile duct ligation (pCL), and ligation of left and median hepatic bile duct with gallbladder removal (LMHL) models. Survival was assessed by Kaplan-Meier method. Fibrotic change was determined by Masson-Trichrome staining and Collagen expression. Overall, 70% (7 of 10) of tCL mice died by day 7, whereas majority 67% (10 of 15) of pCL mice survived with loss of jaundice. A total of 19% (3 of 16) of LMHL mice died; however, jaundice continued beyond day 14, with survival of more than a month. Compensatory enlargement of the right lobe was observed in both pCL and LMHL models. The pCL model demonstrated acute inflammation due to obstructive jaundice 3 d after ligation but jaundice rapidly decreased by day 7. The LHML group developed portal hypertension and severe fibrosis by day 14 in addition to prolonged jaundice. The standard tCL model is too unstable with high mortality for long-term studies. pCL may be an appropriate model for acute inflammation with obstructive jaundice, but long-term survivors are no longer jaundiced. The LHML model was identified to be the most feasible model to study the effect of long-term obstructive jaundice. Copyright © 2016 Elsevier Inc. All rights reserved.

AMMA-CATCH a Hydrological, Meteorological and Ecological Long Term Observatory on West Africa : Some Recent Results

NASA Astrophysics Data System (ADS)

Galle, S.; Grippa, M.; Peugeot, C.; Bouzou Moussa, I.; Cappelaere, B.; Demarty, J.; Mougin, E.; Lebel, T.; Chaffard, V.

2015-12-01

AMMA-CATCH is a multi-scale observation system dedicated to long-term monitoring of the water cycle, the vegetation dynamics and their interaction with climate and water resources in West Africa. In the context of the global change, long-term observations are required to i) gain understanding in eco-hydrological processes over this highly contrasted region, ii) help their representation in Earth System Models, and iii) detect trends and infer their impacts on water resources and living conditions. It is made of three meso-scale sites (~ 1°x1°) in Mali, Niger and Benin, extending along the West African eco-climatic gradient. Within this regional window (5° by 9°), each of the three sites comprises a multi-scale set-up which helps documenting the components of the hydrologic budget and the evolutions of the surface conditions over a range of time scales: raingages, piezometers, river discharge stations, soil moisture and temperature profiles, turbulent fluxes measurements, LAI/biomass monitoring. This observation system has been continuously generating coherent datasets for 10 to 25 years depending on the datasets. It is jointly operated by French and African (Mali, Niger and Benin) research institutions. The data-base is available to the community through the website (www.amma-catch.org). AMMA-CATCH is a member of the French critical zone observatory network "Réseau des Bassins Versants", (RBV). AMMA-CATH participates to several global or regional observation networks, such as FluxNet, CarboAfrica, International Soil Moisture Networks (ISMN) and to calibration/validation campaigns for satellite missions such as SMOS (CNES, ESA), MEGHA-TROPIQUES (France/India) or SWAP(NASA). AMMA-CATCH fills a gap over a region, West Africa, where environmental data are largely lacking, and thus, it can usefully contribute to the international networking effort for environmental monitoring and research. Recent results on regional evolution of land cover, rainfall intensity and

Multifrequency Photo-polarimetric WEBT Observation Campaign on the Blazar S5 0716+714: Source Microvariability and Search for Characteristic Timescales

NASA Astrophysics Data System (ADS)

Bhatta, G.; Stawarz, Ł.; Ostrowski, M.; Markowitz, A.; Akitaya, H.; Arkharov, A. A.; Bachev, R.; Benítez, E.; Borman, G. A.; Carosati, D.; Cason, A. D.; Chanishvili, R.; Damljanovic, G.; Dhalla, S.; Frasca, A.; Hiriart, D.; Hu, S.-M.; Itoh, R.; Jableka, D.; Jorstad, S.; Jovanovic, M. D.; Kawabata, K. S.; Klimanov, S. A.; Kurtanidze, O.; Larionov, V. M.; Laurence, D.; Leto, G.; Marscher, A. P.; Moody, J. W.; Moritani, Y.; Ohlert, J. M.; Di Paola, A.; Raiteri, C. M.; Rizzi, N.; Sadun, A. C.; Sasada, M.; Sergeev, S.; Strigachev, A.; Takaki, K.; Troitsky, I. S.; Ui, T.; Villata, M.; Vince, O.; Webb, J. R.; Yoshida, M.; Zola, S.

2016-11-01

Here we report on the results of the Whole Earth Blazar Telescope photo-polarimetric campaign targeting the blazar S5 0716+71, organized in 2014 March to monitor the source simultaneously in BVRI and near-IR filters. The campaign resulted in an unprecedented data set spanning ∼110 hr of nearly continuous, multiband observations, including two sets of densely sampled polarimetric data mainly in the R filter. During the campaign, the source displayed pronounced variability with peak-to-peak variations of about 30% and “bluer-when-brighter” spectral evolution, consisting of a day-timescale modulation with superimposed hour-long microflares characterized by ∼0.1 mag flux changes. We performed an in-depth search for quasi-periodicities in the source light curve; hints for the presence of oscillations on timescales of ∼3 and ∼5 hr do not represent highly significant departures from a pure red-noise power spectrum. We observed that, at a certain configuration of the optical polarization angle (PA) relative to the PA of the innermost radio jet in the source, changes in the polarization degree (PD) led the total flux variability by about 2 hr; meanwhile, when the relative configuration of the polarization and jet angles altered, no such lag could be noted. The microflaring events, when analyzed as separate pulse emission components, were found to be characterized by a very high PD (>30%) and PAs that differed substantially from the PA of the underlying background component, or from the radio jet positional angle. We discuss the results in the general context of blazar emission and energy dissipation models. ).

MULTIFREQUENCY PHOTO-POLARIMETRIC WEBT OBSERVATION CAMPAIGN ON THE BLAZAR S5 0716+714: SOURCE MICROVARIABILITY AND SEARCH FOR CHARACTERISTIC TIMESCALES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhatta, G.; Stawarz, Ł.; Ostrowski, M.

Here we report on the results of the Whole Earth Blazar Telescope photo-polarimetric campaign targeting the blazar S5 0716+71, organized in 2014 March to monitor the source simultaneously in BVRI and near-IR filters. The campaign resulted in an unprecedented data set spanning ∼110 hr of nearly continuous, multiband observations, including two sets of densely sampled polarimetric data mainly in the R filter. During the campaign, the source displayed pronounced variability with peak-to-peak variations of about 30% and “bluer-when-brighter” spectral evolution, consisting of a day-timescale modulation with superimposed hour-long microflares characterized by ∼0.1 mag flux changes. We performed an in-depth searchmore » for quasi-periodicities in the source light curve; hints for the presence of oscillations on timescales of ∼3 and ∼5 hr do not represent highly significant departures from a pure red-noise power spectrum. We observed that, at a certain configuration of the optical polarization angle (PA) relative to the PA of the innermost radio jet in the source, changes in the polarization degree (PD) led the total flux variability by about 2 hr; meanwhile, when the relative configuration of the polarization and jet angles altered, no such lag could be noted. The microflaring events, when analyzed as separate pulse emission components, were found to be characterized by a very high PD (>30%) and PAs that differed substantially from the PA of the underlying background component, or from the radio jet positional angle. We discuss the results in the general context of blazar emission and energy dissipation models.« less

Dissociation between perceptual processing and priming in long-term lorazepam users.

PubMed

Giersch, Anne; Vidailhet, Pierre

2006-12-01

Acute effects of lorazepam on visual information processing, perceptual priming and explicit memory are well established. However, visual processing and perceptual priming have rarely been explored in long-term lorazepam users. By exploring these functions it was possible to test the hypothesis that difficulty in processing visual information may lead to deficiencies in perceptual priming. Using a simple blind procedure, we tested explicit memory, perceptual priming and visual perception in 15 long-term lorazepam users and 15 control subjects individually matched according to sex, age and education level. Explicit memory, perceptual priming, and the identification of fragmented pictures were found to be preserved in long-term lorazepam users, contrary to what is usually observed after an acute drug intake. The processing of visual contour, on the other hand, was still significantly impaired. These results suggest that the effects observed on low-level visual perception are independent of the acute deleterious effects of lorazepam on perceptual priming. A comparison of perceptual priming in subjects with low- vs. high-level identification of new fragmented pictures further suggests that the ability to identify fragmented pictures has no influence on priming. Despite the fact that they were treated with relatively low doses and far from peak plasma concentration, it is noteworthy that in long-term users memory was preserved.

Short-Term Impact Evaluation of a Social Marketing Campaign to Prevent Syphilis Among Men Who Have Sex With Men

PubMed Central

Darrow, William W.; Biersteker, Susan

2008-01-01

Objectives. We carried out an independent short-term impact evaluation of a social marketing campaign designed to reduce syphilis infections among men who have sex with men in south Florida in 2004. Methods. Venue-based surveys were conducted shortly after the campaign began and 6 months later to assess changes in exposure to campaign materials, awareness, knowledge about syphilis, perceptions of risk, sexual behavior, clinic visits, and testing and treatment for syphilis among participants. Results. Exposure to social marketing campaign materials increased from 18.0% at baseline to 36.5% at follow-up (P< .001). Awareness of syphilis and perceptions of risk increased among Broward County residents but not among Miami–Dade County residents. Risky sexual practices and patterns of recreational drug use did not change. No significant increases in knowledge, clinic visits, or testing or treatment for syphilis among participants were detected over the 6-month study period. Conclusions. None of the campaign objectives were fully met. The interventions were insufficient to produce a significant impact among men who have sex with men in south Florida. PMID:18172146

Short-term impact evaluation of a social marketing campaign to prevent syphilis among men who have sex with men.

PubMed

Darrow, William W; Biersteker, Susan

2008-02-01

We carried out an independent short-term impact evaluation of a social marketing campaign designed to reduce syphilis infections among men who have sex with men in south Florida in 2004. Venue-based surveys were conducted shortly after the campaign began and 6 months later to assess changes in exposure to campaign materials, awareness, knowledge about syphilis, perceptions of risk, sexual behavior, clinic visits, and testing and treatment for syphilis among participants. Exposure to social marketing campaign materials increased from 18.0% at baseline to 36.5% at follow-up (P< .001). Awareness of syphilis and perceptions of risk increased among Broward County residents but not among Miami-Dade County residents. Risky sexual practices and patterns of recreational drug use did not change. No significant increases in knowledge, clinic visits, or testing or treatment for syphilis among participants were detected over the 6-month study period. None of the campaign objectives were fully met. The interventions were insufficient to produce a significant impact among men who have sex with men in south Florida.

Compensation for PKMζ in long-term potentiation and spatial long-term memory in mutant mice.

PubMed

Tsokas, Panayiotis; Hsieh, Changchi; Yao, Yudong; Lesburguères, Edith; Wallace, Emma Jane Claire; Tcherepanov, Andrew; Jothianandan, Desingarao; Hartley, Benjamin Rush; Pan, Ling; Rivard, Bruno; Farese, Robert V; Sajan, Mini P; Bergold, Peter John; Hernández, Alejandro Iván; Cottrell, James E; Shouval, Harel Z; Fenton, André Antonio; Sacktor, Todd Charlton

2016-05-17

PKMζ is a persistently active PKC isoform proposed to maintain late-LTP and long-term memory. But late-LTP and memory are maintained without PKMζ in PKMζ-null mice. Two hypotheses can account for these findings. First, PKMζ is unimportant for LTP or memory. Second, PKMζ is essential for late-LTP and long-term memory in wild-type mice, and PKMζ-null mice recruit compensatory mechanisms. We find that whereas PKMζ persistently increases in LTP maintenance in wild-type mice, PKCι/λ, a gene-product closely related to PKMζ, persistently increases in LTP maintenance in PKMζ-null mice. Using a pharmacogenetic approach, we find PKMζ-antisense in hippocampus blocks late-LTP and spatial long-term memory in wild-type mice, but not in PKMζ-null mice without the target mRNA. Conversely, a PKCι/λ-antagonist disrupts late-LTP and spatial memory in PKMζ-null mice but not in wild-type mice. Thus, whereas PKMζ is essential for wild-type LTP and long-term memory, persistent PKCι/λ activation compensates for PKMζ loss in PKMζ-null mice.

Long-Term Variability of Airborne Asian Dust Observed from TOMS

NASA Technical Reports Server (NTRS)

Herman, J. R.; Hsu, N. C.; Seftor, C. J.; Holben, B. N.; Holben, B. N.; Einaudi, Franco (Technical Monitor)

2001-01-01

Recent studies suggest that airborne Asian dust may not only play an important role in the regional radiation budget, but also influence the air quality over North America through long-range transport. In this paper, we use satellite data to investigate the long-term variability of airborne Asian dust as well as the daily variation of the dust aerosol distribution. By combining the Total Ozone Mapping Spectrometer (TOMS) aerosol index with National Centers for Environmental Prediction (NCEP) wind data, our analysis shows a strong correlation between the generation of dust storms in the region and the passage of springtime weather fronts. This is consistent with earlier studies performed by other researchers. According to both the Nimbus-7 and Earth-Probe TOMS data the Takla Makan desert, the Gobi desert, and the and region of Inner Mongolia are major sources of the eastward-flowing airborne Asian dust. Heavily populated areas in eastern China (e.g., Beijing) are often on the primary path of the dust storms originating in these desert regions. The increasing desertification north of the Beijing region has served to exacerbate problems stemming from these storms. The time series derived from 20 years of TOMS aerosol index data shows the first significant satellite evidence of the atmospheric effect of increasing desertification, indicating that the amount of dust blown eastward has increased strongly during the past few years including the year 2000.

On long-term ozone trends at Hohenpeissenberg

NASA Technical Reports Server (NTRS)

Claude, H.; Vandersee, W.; Wege, K.

1994-01-01

More than 2000 ozone soundings and a large number of Dobson observations have been performed since 1967 in a unique procedure. The achieved very homogeneous data sets were used to evaluate significant long-term trends both in the troposphere and the stratosphere. The trend amounts to about plus 2 percent per year in the troposphere and to about minus 0.5 percent per year in the stratosphere. Extremely low ozone records obtained during winter 1991/92 are discussed in the light of the long term series. The winter mean of the ozone column is the lowest one of the series. The ozone deficit occurred mainly in the lower stratosphere. One cause may be the Pinatubo cloud. Even compared with the extreme winter mean following the El Chichon eruption the ozone content was lower. Additionally ozone was reduced by dynamical effects due to unusual weather situations.

Long-Term Evaluation of the AMSR-E Soil Moisture Product Over the Walnut Gulch Watershed, AZ

NASA Astrophysics Data System (ADS)

Bolten, J. D.; Jackson, T. J.; Lakshmi, V.; Cosh, M. H.; Drusch, M.

2005-12-01

The Advanced Microwave Scanning Radiometer -Earth Observing System (AMSR-E) was launched aboard NASA's Aqua satellite on May 4th, 2002. Quantitative estimates of soil moisture using the AMSR-E provided data have required routine radiometric data calibration and validation using comparisons of satellite observations, extended targets and field campaigns. The currently applied NASA EOS Aqua ASMR-E soil moisture algorithm is based on a change detection approach using polarization ratios (PR) of the calibrated AMSR-E channel brightness temperatures. To date, the accuracy of the soil moisture algorithm has been investigated on short time scales during field campaigns such as the Soil Moisture Experiments in 2004 (SMEX04). Results have indicated self-consistency and calibration stability of the observed brightness temperatures; however the performance of the moisture retrieval algorithm has been poor. The primary objective of this study is to evaluate the quality of the current version of the AMSR-E soil moisture product for a three year period over the Walnut Gulch Experimental Watershed (150 km2) near Tombstone, AZ; the northern study area of SMEX04. This watershed is equipped with hourly and daily recording of precipitation, soil moisture and temperature via a network of raingages and a USDA-NRCS Soil Climate Analysis Network (SCAN) site. Surface wetting and drying are easily distinguished in this area due to the moderately-vegetated terrain and seasonally intense precipitation events. Validation of AMSR-E derived soil moisture is performed from June 2002 to June 2005 using watershed averages of precipitation, and soil moisture and temperature data from the SCAN site supported by a surface soil moisture network. Long-term assessment of soil moisture algorithm performance is investigated by comparing temporal variations of moisture estimates with seasonal changes and precipitation events. Further comparisons are made with a standard soil dataset from the European

The requirement for enhanced CREB1 expression in consolidation of long-term synaptic facilitation and long-term excitability in sensory neurons of Aplysia

PubMed Central

Liu, Rong-Yu; Cleary, Leonard J.; Byrne, John H.

2011-01-01

Accumulating evidence suggests that the transcriptional activator CREB1 is important for serotonin (5-HT)-induced long-term facilitation (LTF) of the sensorimotor synapse in Aplysia. Moreover, creb1 is among the genes activated by CREB1, suggesting a role for this protein beyond the induction phase of LTF. The time course of the requirement for CREB1 synthesis in the consolidation of long-term facilitation was examined using RNA interference (RNAi) techniques in sensorimotor co-cultures. Injection of CREB1 small-interfering RNA (siRNA) immediately or 10 h after 5-HT treatment blocked LTF when measured at 24 h and 48 h after treatment. In contrast, CREB1 siRNA did not block LTF when injected 16 h after 5-HT treatment. These results demonstrate that creb1 expression must be sustained for a relatively long time in order to support the consolidation of LTF. In addition, LTF is also accompanied by a long-term increase in the excitability (LTE) of sensory neurons (SNs). Because LTE was observed in the isolated SN after 5-HT treatment, this long-term change was intrinsic to that element of the circuit. LTE was blocked when CREB1 siRNA was injected into isolated SNs immediately after 5-HT treatment. These data suggest that 5-HT-induced CREB1 synthesis is required for consolidation of both LTF and LTE. PMID:21543617

Long-Term Opioid Therapy Reconsidered

PubMed Central

Von Korff, Michael; Kolodny, Andrew; Deyo, Richard A.; Chou, Roger

2012-01-01

In the past 20 years, primary care physicians have greatly increased prescribing of long-term opioid therapy. However, the rise in opioid prescribing has outpaced the evidence regarding this practice. Increased opioid availability has been accompanied by an epidemic of opioid abuse and overdose. The rate of opioid addiction among patients receiving long-term opioid therapy remains unclear, but research suggests that opioid misuse is not rare. Recent studies report increased risks for serious adverse events, including fractures, cardiovascular events, and bowel obstruction, although further research on medical risks is needed. New data indicate that opioid-related risks may increase with dose. From a societal perspective, higher-dose regimens account for the majority of opioids dispensed, so cautious dosing may reduce both diversion potential and patient risks for adverse effects. Limiting long-term opioid therapy to patients for whom it provides decisive benefits could also reduce risks. Given the warning signs and knowledge gaps, greater caution and selectivity are needed in prescribing long-term opioid therapy. Until stronger evidence becomes available, clinicians should err on the side of caution when considering this treatment. PMID:21893626

Effect of long-term and short-term progestagen treatment on follicular development and pregnancy rate in cyclic ewes.

PubMed

Viñoles, C; Forsberg, M; Banchero, G; Rubianes, E

2001-03-01

The aim of this study was to evaluate the effect of the length of a progestagen treatment (12 d vs. 6 d) on follicular dynamics, estrus synchronization and pregnancy rate using medroxyprogesterone acetate (MAP) with or without an eCG dose at the end of MAP treatment. One hundred sixty Polwarth ewes were divided into four equal groups: long-term treated (LT, n=40); short-term treated (ST, n=40); long-term treated plus eCG (LTeCG, n=40); and short-term treated plus eCG (STeCG, n=40). Five ewes of each group were separated to undergo daily transrectal ultrasonography, and blood samples were taken for hormone determination. Until 96 h after sponge withdrawal the number of ewes in estrus was higher in both long-term-treated groups than in both short-term-treated groups but at the end of the observational period (144 h) no significant differences were found among groups. The pregnancy rate was higher in the ST group (87%) than in the other groups (LT, 63%; LTeCG, 67%; and STeCG, 58%; P< or =0.03). The ovulatory follicle emerged before sponge withdrawal in long-term-treated ewes (-3.8+/-0.4 d and -2.2+/-0.8 d for LT and LTeCG, respectively), whereas in short-term-treated ewes it emerges around sponge removal (0.4+/-1.1 d and 0.5+/-0.5 d for ST and STeCG, respectively; P< or =0.01). The ovulatory follicle in the LT group had a longer lifespan and attained a larger (P< or =0.05) maximum diameter than in the ST group. We conclude: a) that the lower pregnancy rate observed after long-term progestagen treatment was related to a slower follicular turnover that promoted the ovulation of persistent dominant follicles; (b) that short-term treatment resulted in a higher pregnancy rate probably due to the ovulation of newly recruited growing follicles; and (c) treatment with eCG had no advantage in association with long-term treatment and had a deleterious effect in combination with short-term treatment with MAP.

The NANOGrav Observing Program: Automation and Reproducibility

NASA Astrophysics Data System (ADS)

Brazier, Adam; Cordes, James; Demorest, Paul; Dolch, Timothy; Ferdman, Robert; Garver-Daniels, Nathaniel; Hawkins, Steven; Lam, Michael Timothy; Lazio, T. Joseph W.

2018-01-01

The NANOGrav Observing Program is a decades-long search for gravitational waves using pulsar timing which relies, for its sensitivity, on large data sets from observations of many pulsars. These are constructed through an intensive, long-term observing campaign. The nature of the program requires automation in the transfer and archiving of the large volume of raw telescope data, the calibration of those data, and making these resulting data products—required for diagnostic and data exploration purposes—available to NANOGrav members. Reproducibility of results is a key goal in this project, and essential to its success; it requires treating the software itself as a data product of the research, while ensuring easy access by, and collaboration between, members of NANOGrav, the International Pulsar Timing Array consortium (of which NANOGrav is a key member), as well as the wider astronomy community and the public.

Long-term eclipse timing of white dwarf binaries: an observational hint of a magnetic mechanism at work

NASA Astrophysics Data System (ADS)

Bours, M. C. P.; Marsh, T. R.; Parsons, S. G.; Dhillon, V. S.; Ashley, R. P.; Bento, J. P.; Breedt, E.; Butterley, T.; Caceres, C.; Chote, P.; Copperwheat, C. M.; Hardy, L. K.; Hermes, J. J.; Irawati, P.; Kerry, P.; Kilkenny, D.; Littlefair, S. P.; McAllister, M. J.; Rattanasoon, S.; Sahman, D. I.; Vučković, M.; Wilson, R. W.

2016-08-01

We present a long-term programme for timing the eclipses of white dwarfs in close binaries to measure apparent and/or real variations in their orbital periods. Our programme includes 67 close binaries, both detached and semi-detached and with M-dwarfs, K-dwarfs, brown dwarfs or white dwarfs secondaries. In total, we have observed more than 650 white dwarf eclipses. We use this sample to search for orbital period variations and aim to identify the underlying cause of these variations. We find that the probability of observing orbital period variations increases significantly with the observational baseline. In particular, all binaries with baselines exceeding 10 yr, with secondaries of spectral type K2 - M5.5, show variations in the eclipse arrival times that in most cases amount to several minutes. In addition, among those with baselines shorter than 10 yr, binaries with late spectral type (>M6), brown dwarf or white dwarf secondaries appear to show no orbital period variations. This is in agreement with the so-called Applegate mechanism, which proposes that magnetic cycles in the secondary stars can drive variability in the binary orbits. We also present new eclipse times of NN Ser, which are still compatible with the previously published circumbinary planetary system model, although only with the addition of a quadratic term to the ephemeris. Finally, we conclude that we are limited by the relatively short observational baseline for many of the binaries in the eclipse timing programme, and therefore cannot yet draw robust conclusions about the cause of orbital period variations in evolved, white dwarf binaries.

Using Workflow Diagrams to Address Hand Hygiene in Pediatric Long-Term Care Facilities1

PubMed Central

Carter, Eileen J.; Cohen, Bevin; Murray, Meghan T.; Saiman, Lisa; Larson, Elaine L.

2015-01-01

Hand hygiene (HH) in pediatric long-term care settings has been found to be sub-optimal. Multidisciplinary teams at three pediatric long-term care facilities developed step-by-step workflow diagrams of commonly performed tasks highlighting HH opportunities. Diagrams were validated through observation of tasks and concurrent diagram assessment. Facility teams developed six workflow diagrams that underwent 22 validation observations. Four main themes emerged: 1) diagram specificity, 2) wording and layout, 3) timing of HH indications, and 4) environmental hygiene. The development of workflow diagrams is an opportunity to identify and address the complexity of HH in pediatric long-term care facilities. PMID:25773517

Development of Download System for Waveform Data Observed at Long-Term Borehole Monitoring System installed in the Nankai Trough

NASA Astrophysics Data System (ADS)

Tsuboi, Seiji; Horikawa, Hiroki; Takaesu, Morifumi; Sueki, Kentaro; Araki, Eiichiro; Sonoda, Akira; Takahashi, Narumi

2016-04-01

The Nankai Trough in southwest Japan is one of most active subduction zone in the world. Great mega-thrust earthquakes repeatedly occurred every 100 to 150 years in this area, it's anticipated to occur in the not distant future. For the purpose of elucidation of the history of mega-splay fault activity, the physical properties of the geological strata and the internal structure of the accretionary prism, and monitoring of diastrophism in this area, we have a plan, Nankai Trough Seismogenic Zone Experiments (NanTroSEIZE), as a part of Integrated Ocean Drilling Program (IODP). We have a plan to install the borehole observation system in a few locations by the NanTroSEIZE. This system is called Long-Term Borehole Monitoring System, it consists of various sensors in the borehole such as a broadband seismometer, a tiltmeter, a strainmeter, geophones and accelerometer, thermometer array as well as pressure ports for pore-fluid pressure monitoring. The signal from sensors is transmitted to DONET (Dense Ocean-floor Network System for Earthquake and Tsunamis) in real time. During IODP Exp. 332 in December 2010, the first Long-Term Borehole Monitoring System was installed into the C0002 borehole site located 80 km off the Kii Peninsula, 1938 m water depth in the Nankai Trough. We have developed a web application system for data download, Long-Term Borehole Monitoring Data Site. Based on a term and sensors which user selected on this site, user can download monitoring waveform data (e.g. broadband seismometer data, accelerometer data, strainmeter data, tiltmeter data) in near real-time. This system can make the arbitrary data which user selected a term and sensors, and download it simply. Downloadable continuous data is provided in seed format, which includes sensor informations. In addition, before data download, user can check that data is abailable or not by data check function. In this presentation, we show our web application system and discuss our future plans for

Long-term follow-up of psilocybin-facilitated smoking cessation.

PubMed

Johnson, Matthew W; Garcia-Romeu, Albert; Griffiths, Roland R

2017-01-01

A recent open-label pilot study (N = 15) found that two to three moderate to high doses (20 and 30 mg/70 kg) of the serotonin 2A receptor agonist, psilocybin, in combination with cognitive behavioral therapy (CBT) for smoking cessation, resulted in substantially higher 6-month smoking abstinence rates than are typically observed with other medications or CBT alone. To assess long-term effects of a psilocybin-facilitated smoking cessation program at ≥12 months after psilocybin administration. The present report describes biologically verified smoking abstinence outcomes of the previous pilot study at ≥12 months, and related data on subjective effects of psilocybin. All 15 participants completed a 12-month follow-up, and 12 (80%) returned for a long-term (≥16 months) follow-up, with a mean interval of 30 months (range = 16-57 months) between target-quit date (i.e., first psilocybin session) and long-term follow-up. At 12-month follow-up, 10 participants (67%) were confirmed as smoking abstinent. At long-term follow-up, nine participants (60%) were confirmed as smoking abstinent. At 12-month follow-up 13 participants (86.7%) rated their psilocybin experiences among the five most personally meaningful and spiritually significant experiences of their lives. These results suggest that in the context of a structured treatment program, psilocybin holds considerable promise in promoting long-term smoking abstinence. The present study adds to recent and historical evidence suggesting high success rates when using classic psychedelics in the treatment of addiction. Further research investigating psilocybin-facilitated treatment of substance use disorders is warranted.

Rigidity and definition of Caribbean plate motion from COCONet and campaign GPS observations

NASA Astrophysics Data System (ADS)

Mattioli, Glen; Miller, Jamie; DeMets, Charles; Jansma, Pamela

2014-05-01

The currently accepted kinematic model of the Caribbean plate presented by DeMets et al. (2007) is based on velocities from 6 continuous and 14 campaign GPS sites. COCONet is a multi-hazard GPS-Met observatory, which extends the existing infrastructure of the Plate Boundary Observatory in North America into the Caribbean basin. In 2010, UNAVCO in collaboration with UCAR, was funded by NSF to design, build, and initially maintain a network of 50 new cGPS/Met sites and include data from another 50 existing sites in the Caribbean region. The current COCONet siting plan calls for 46 new stations, 21 refurbished stations, and 77 existing stations across 26 nations in the Caribbean region. Data from all COCONet sites flow into the UNAVCO archive and are processed by the PBO analysis centers and are also processed independently by the UTA Geodesy Lab using GIPSY-OASISII (v.6.2) using an absolute point positioning strategy and final, precise orbits, clocks, and Earth orientation parameters from JPL in the IGS08 frame. We present here our refined estimate of Caribbean plate motion by evaluating data from an expanded number of stations with an improved spatial distribution. In order to better constrain the eastern margin of the plate near the Lesser Antilles subduction interface, campaign GPS observations have been collected on the island of Dominica over the last decade. These are combined with additional campaign observations from the western Caribbean, specifically from Honduras and Nicaragua. We have analyzed a total of 117 sites from the Caribbean region, including campaign data and the data from the cGPS stations that comprise COCONet. An updated velocity field for the Caribbean plate is presented and an inversion of the velocities for 24 sites yields a plate angular velocity that differs from previously published models. Our best fitting inversion to GPS velocities from these 24 sites suggests that 2-plate model for the Caribbean is required to fit the GPS

Rigidity and definition of Caribbean plate motion from COCONet and campaign GPS observations

NASA Astrophysics Data System (ADS)

Mattioli, G. S.; Miller, J. A.; DeMets, C.; Jansma, P. E.

2015-12-01

The kinematic model of the Caribbean plate presented by DeMets et al. (2007) is based on velocities from 6 continuous and 14 campaign GPS sites. COCONet is a multi-hazard GPS-Met observatory, which extends the existing infrastructure of the PBO in North America into the Caribbean basin. In 2010, UNAVCO in collaboration with UCAR, was funded by NSF to design, build, and initially maintain a network of 50 new cGPS/Met sites and include data from another 50 existing sites in the Caribbean region. The COCONet siting plan is for 46 new stations, 21 refurbished stations, and 77 existing stations across 26 nations in the Caribbean region. Data from all COCONet sites flow into the UNAVCO archive and are processed by the PBO analysis centers and are also processed independently by the UTA Geodesy Lab using GIPSY-OASISII (v.6.3) using an APP strategy and final, precise orbits, clocks, and EOP from JPL in the IGS08r frame. We present a refined estimate of Caribbean plate motion by evaluating data from an expanded number of stations with an improved spatial distribution. In order to better constrain the eastern margin of the plate near the Lesser Antilles subduction interface, campaign GPS observations have been collected on the island of Dominica over the last decade. These are combined with additional campaign observations from the western Caribbean, specifically from Honduras and Nicaragua. We have analyzed a total of 117 sites from the Caribbean region, including campaign data and the data from the cGPS stations that comprise COCONet. An updated velocity field for the Caribbean plate is presented and an inversion of the velocities for 24 sites yields a plate angular velocity that differs from previously published models. Our best fitting inversion to GPS velocities from these 24 sites suggests that 2-plate model for the Caribbean is required to fit the GPS observations, which implies that the Caribbean is undergoing modest (1-3 mm/yr) deformation within its interior. Some

Long-term care in international perspective.

PubMed

Doty, P

1988-12-01

The findings of a study of long-term care policies in 18 countries are reported in this article. Initial data were collected by a questionnaire survey under the auspices of the International Social Security Association. These data were supplemented by published documents and government statistics obtained while researching long-term care for the International Social Security Association and, subsequently, for the Organization for Economic Cooperation and Development. The principal focus is a cross-national comparison of institutionalization rates for the elderly. Differences in use rates for medically oriented facilities are less than those for nonmedical residential long-term care facilities. Only a small amount of variation is related to demographic differences, such as older or more female elderly populations in those countries with higher institutionalization rates. Included also is a description of the modes of financing long-term care.

Effectiveness of media awareness campaigns on the proportion of vehicles that give space to ambulances on roads: An observational study.

PubMed

Shaikh, Shiraz; Baig, Lubna A; Polkowski, Maciej

2017-01-01

The findings of the Health Care in Danger project in Karachi suggests that there is presence of behavioral negligence among vehicle operators on roads in regards to giving way to ambulances. A mass media campaign was conducted to raise people's awareness on the importance of giving way to ambulances. The main objective of this study was to determine the effectiveness of the campaign on increasing the proportion of vehicles that give way to ambulances. This was a quasi-experimental study that was based on before and after design. Three observation surveys were carried out in different areas of the city in Karachi, Pakistan before, during and after the campaign by trained observers who recorded their findings on a checklist. Each observation was carried out at three different times of the day for at least two days on each road. The relationship of the media campaign with regards to a vehicle giving space to an ambulance was calculated by means of odds ratios and 95% confidence intervals using multivariate logistic regression. Overall, 245 observations were included in the analysis. Traffic congestion and negligence/resistance, by vehicles operators who were in front of the ambulance, were the two main reasons why ambulances were not given way. Other reasons include: sudden stops by minibuses and in the process causing obstruction, ambulances not rushing through to alert vehicle operators to give way and traffic interruption by VIP movement. After adjustment for site, time of day, type of ambulance and number of cars in front of the ambulance, vehicles during (OR=2.13, 95% CI=1.22-3.71, p=0.007) and after the campaign (OR=1.73, 95% CI=1.02-2.95, p=0.042) were significantly more likely give space to ambulances. Mass media campaigns can play a significant role in changing the negligent behavior of people, especially when the campaign conveys a humanitarian message such as: giving way to ambulances can save lives.

Effectiveness of media awareness campaigns on the proportion of vehicles that give space to ambulances on roads: An observational study

PubMed Central

Shaikh, Shiraz; Baig, Lubna A; Polkowski, Maciej

2017-01-01

Background and Objective: The findings of the Health Care in Danger project in Karachi suggests that there is presence of behavioral negligence among vehicle operators on roads in regards to giving way to ambulances. A mass media campaign was conducted to raise people’s awareness on the importance of giving way to ambulances. The main objective of this study was to determine the effectiveness of the campaign on increasing the proportion of vehicles that give way to ambulances. Methods: This was a quasi-experimental study that was based on before and after design. Three observation surveys were carried out in different areas of the city in Karachi, Pakistan before, during and after the campaign by trained observers who recorded their findings on a checklist. Each observation was carried out at three different times of the day for at least two days on each road. The relationship of the media campaign with regards to a vehicle giving space to an ambulance was calculated by means of odds ratios and 95% confidence intervals using multivariate logistic regression. Results: Overall, 245 observations were included in the analysis. Traffic congestion and negligence/resistance, by vehicles operators who were in front of the ambulance, were the two main reasons why ambulances were not given way. Other reasons include: sudden stops by minibuses and in the process causing obstruction, ambulances not rushing through to alert vehicle operators to give way and traffic interruption by VIP movement. After adjustment for site, time of day, type of ambulance and number of cars in front of the ambulance, vehicles during (OR=2.13, 95% CI=1.22-3.71, p=0.007) and after the campaign (OR=1.73, 95% CI=1.02-2.95, p=0.042) were significantly more likely give space to ambulances. Conclusion: Mass media campaigns can play a significant role in changing the negligent behavior of people, especially when the campaign conveys a humanitarian message such as: giving way to ambulances can save lives

Tracking Trends in Fractional Forest Cover Change using Long Term Data from AVHRR and MODIS

NASA Astrophysics Data System (ADS)

Kim, D. H.; DiMiceli, C.; Sohlberg, R. A.; Hansen, M.; Carroll, M.; Kelly, M.; Townshend, J. R.

2014-12-01

Tree cover affects terrestrial energy and water exchanges, photosynthesis and transpiration, net primary production, and carbon and nutrient fluxes. Accurate and long-term continuous observation of tree cover change is critical for the study of the gradual ecosystem change. Tree cover is most commonly inferred from categorical maps which may inadequately represent within-class heterogeneity for many analyses. Alternatively, Vegetation Continuous Fields data measures fractions or proportions of pixel area. Recent development in remote sensing data processing and cross sensor calibration techniques enabled the continuous, long-term observations such as Land Long-Term Data Records. Such data products and their surface reflectance data have enhanced the possibilities for long term Vegetation Continuous Fields data, thus enabling the estimation of long term trend of fractional forest cover change. In this presentation, we will summarize the progress in algorithm development including automation of training selection for deciduous and evergreen forest, the preliminary results, and its future applications to relate trends in fractional forest cover change and environmental change.

Competitive short-term and long-term memory processes in spatial habituation.

PubMed

Sanderson, David J; Bannerman, David M

2011-04-01

Exposure to a spatial location leads to habituation of exploration such that, in a novelty preference test, rodents subsequently prefer exploring a novel location to the familiar location. According to Wagner's (1981) theory of memory, short-term and long-term habituation are caused by separate and sometimes opponent processes. In the present study, this dual-process account of memory was tested. Mice received a series of exposure training trials to a location before receiving a novelty preference test. The novelty preference was greater when tested after a short, rather than a long, interval. In contrast, the novelty preference was weaker when exposure training trials were separated by a short, rather than a long interval. Furthermore, it was found that long-term habituation was determined by the independent effects of the amount of exposure training and the number of exposure training trials when factors such as the intertrial interval and the cumulative intertrial interval were controlled. A final experiment demonstrated that a long-term reduction of exploration could be caused by a negative priming effect due to associations formed during exploration. These results provide evidence against a single-process account of habituation and suggest that spatial habituation is determined by both short-term, recency-based memory and long-term, incrementally strengthened memory.

Compensation for PKMζ in long-term potentiation and spatial long-term memory in mutant mice

PubMed Central

Tsokas, Panayiotis; Hsieh, Changchi; Yao, Yudong; Lesburguères, Edith; Wallace, Emma Jane Claire; Tcherepanov, Andrew; Jothianandan, Desingarao; Hartley, Benjamin Rush; Pan, Ling; Rivard, Bruno; Farese, Robert V; Sajan, Mini P; Bergold, Peter John; Hernández, Alejandro Iván; Cottrell, James E; Shouval, Harel Z; Fenton, André Antonio; Sacktor, Todd Charlton

2016-01-01

PKMζ is a persistently active PKC isoform proposed to maintain late-LTP and long-term memory. But late-LTP and memory are maintained without PKMζ in PKMζ-null mice. Two hypotheses can account for these findings. First, PKMζ is unimportant for LTP or memory. Second, PKMζ is essential for late-LTP and long-term memory in wild-type mice, and PKMζ-null mice recruit compensatory mechanisms. We find that whereas PKMζ persistently increases in LTP maintenance in wild-type mice, PKCι/λ, a gene-product closely related to PKMζ, persistently increases in LTP maintenance in PKMζ-null mice. Using a pharmacogenetic approach, we find PKMζ-antisense in hippocampus blocks late-LTP and spatial long-term memory in wild-type mice, but not in PKMζ-null mice without the target mRNA. Conversely, a PKCι/λ-antagonist disrupts late-LTP and spatial memory in PKMζ-null mice but not in wild-type mice. Thus, whereas PKMζ is essential for wild-type LTP and long-term memory, persistent PKCι/λ activation compensates for PKMζ loss in PKMζ-null mice. DOI: http://dx.doi.org/10.7554/eLife.14846.001 PMID:27187150

Long-term effects of interference on short-term memory performance in the rat

PubMed Central

Missaire, Mégane; Fraize, Nicolas; Joseph, Mickaël Antoine; Hamieh, Al Mahdy; Parmentier, Régis; Marighetto, Aline; Salin, Paul Antoine; Malleret, Gaël

2017-01-01

A distinction has always been made between long-term and short-term memory (also now called working memory, WM). The obvious difference between these two kinds of memory concerns the duration of information storage: information is supposedly transiently stored in WM while it is considered durably consolidated into long-term memory. It is well acknowledged that the content of WM is erased and reset after a short time, to prevent irrelevant information from proactively interfering with newly stored information. In the present study, we used typical WM radial maze tasks to question the brief lifespan of spatial WM content in rodents. Groups of rats were submitted to one of two different WM tasks in a radial maze: a WM task involving the repetitive presentation of a same pair of arms expected to induce a high level of proactive interference (PI) (HIWM task), or a task using a different pair in each trial expected to induce a low level of PI (LIWM task). Performance was effectively lower in the HIWM group than in LIWM in the final trial of each training session, indicative of a “within-session/short-term” PI effect. However, we also observed a different “between-session/long-term” PI effect between the two groups: while performance of LIWM trained rats remained stable over days, the performance of HIWM rats dropped after 10 days of training, and this impairment was visible from the very first trial of the day, hence not attributable to within-session PI. We also showed that a 24 hour-gap across training sessions known to allow consolidation processes to unfold, was a necessary and sufficient condition for the long-term PI effect to occur. These findings suggest that in the HIWM task, WM content was not entirely reset between training sessions and that, in specific conditions, WM content can outlast its purpose by being stored more permanently, generating a long-term deleterious effect of PI. The alternative explanation is that WM content could be transferred and

Long-Term Changes in Lower Tropospheric Baseline Ozone Concentrations:. [Comparing Chemistry-Climate Models and Observations at Northern Mid-Latitudes

NASA Technical Reports Server (NTRS)

Parrish, D. D.; Lamarque, J.-F.; Naik, V.; Horowitz, L.; Shindell, D. T.; Staehelin, J.; Derwent, R.; Cooper, O. R.; Tanimoto, H.; Volz-Thomas, A.;

Backcasting long-term climate data: evaluation of hypothesis

NASA Astrophysics Data System (ADS)

Saghafian, Bahram; Aghbalaghi, Sara Ghasemi; Nasseri, Mohsen

2018-05-01

Most often than not, incomplete datasets or short-term recorded data in vast regions impedes reliable climate and water studies. Various methods, such as simple correlation with stations having long-term time series, are practiced to infill or extend the period of observation at stations with missing or short-term data. In the current paper and for the first time, the hypothesis on the feasibility of extending the downscaling concept to backcast local observation records using large-scale atmospheric predictors is examined. Backcasting is coined here to contrast forecasting/projection; the former is implied to reconstruct in the past, while the latter represents projection in the future. To assess our hypotheses, daily and monthly statistical downscaling models were employed to reconstruct past precipitation data and lengthen the data period. Urmia and Tabriz synoptic stations, located in northwestern Iran, constituted two case study stations. SDSM and data-mining downscaling model (DMDM) daily as well as the group method of data handling (GMDH) and model tree (Mp5) monthly downscaling models were trained with National Center for Environmental Prediction (NCEP) data. After training, reconstructed precipitation data of the past was validated against observed data. Then, the data was fully extended to the 1948 to 2009 period corresponding to available NCEP data period. The results showed that DMDM performed superior in generation of monthly average precipitation compared with the SDSM, Mp5, and GMDH models, although none of the models could preserve the monthly variance. This overall confirms practical value of the proposed approach in extension of the past historic data, particularly for long-term climatological and water budget studies.

VLF campaign during the total eclipse of July 22nd, 2009: Observational results and interpretations

NASA Astrophysics Data System (ADS)

Chakrabarti, S. K.; Pal, S.; Sasmal, S.; Mondal, S. K.; Ray, S.; Basak, T.; Maji, S. K.; Khadka, B.; Bhowmick, D.; Chowdhury, A. K.

2012-09-01

A Total Solar Eclipse (TSE) provides us with an exciting opportunity to study the VLF propagation effects under a controlled experimental condition where the extreme ultraviolet and the X-rays from the sun are totally blocked by the moon. During the total eclipse of July 22nd, 2009, the Indian Centre for Space Physics conducted a VLF campaign to obtain the signal from a dozen of places in the Indian sub-continent. Six of these locations gave very good and noise-free data. In some of these data, the signal amplitude is found to be higher than that at non-eclipse condition, while in some other places, it is lower. We present the results of our campaign and give an interpretation of the results using the Long Wavelength Propagation Capability (LWPC) code in a perturbed waveguide both for the easterly and westerly propagation paths.

Business Students' Choice of Short-Term or Long-Term Study Abroad Opportunities

ERIC Educational Resources Information Center

Fitzsimmons, Stacey R.; Flanagan, David J.; Wang, Xiaodan

2013-01-01

Recent years have seen a proliferation of short-term study abroad opportunities. Although they are both supplementing and replacing semester-long study abroad programs, research has focused primarily on semester (long-term) programs. We draw on the theory of planned behavior (TPB) to explore factors that predict why students choose long-term and…

Evaluation of Long-term Soil Moisture Proxies in the U.S. Great Plains

NASA Astrophysics Data System (ADS)

Yuan, S.; Quiring, S. M.

2016-12-01

Soil moisture plays an important role in land-atmosphere interactions through both surface energy and water balances. However, despite its importance, there are few long-term records of observed soil moisture for investigating long-term spatial and temporal variations of soil moisture. Hence, it is necessary to find suitable approximations of soil moisture observations. 5 drought indices will be compared with simulated and observed soil moisture over the U.S. Great Plains during two time periods (1980 - 2012 and 2003 - 2012). Standardized Precipitation Index (SPI), Standardized Precipitation-Evapotranspiration Index (SPEI), Palmer Z Index (zindex) and Crop Moisture Index (CMI) will be calculated by PRISM data. The soil moisture simulations will be derived from NLDAS. In situ soil moisture will be obtained from North American Soil Moisture Database. The evaluation will focus on three main aspects: trends, variations and persistence. The results will support further research investigating long-term variations in soil moisture-climate interactions.

Seismic Study of the Subsurface Structure and Dynamics of the Solar Interior from High Spatial Resolution Observations

NASA Technical Reports Server (NTRS)

Korzennik, Sylvain G.

1997-01-01

We have carried out the data reduction and analysis of Mt. Wilson 60' solar tower high spatial resolution observations. The reduction of the 100-day-long summer of 1990 observation campaign in terms of rotational splittings was completed leading to an excess of 600,000 splittings. The analysis of these splittings lead to a new inference of the solar internal rotation rate as a function of depth and latitude.

Long-Term Hearing Results After Ossiculoplasty.

PubMed

Cox, Matthew D; Trinidade, Aaron; Russell, James Shep; Dornhoffer, John L

2017-04-01

To determine if the OOPS index is predictive of long-term hearing results after ossiculoplasty. Case series with retrospective chart review. Tertiary care otology practice. Adult and pediatric patients (3-88 years of age). Ossiculoplasty with cartilage tympanoplasty, with or without mastoidectomy. Primary outcome measures included short-term hearing results (pure-tone average air-bone gap [PTA-ABG] measured between 60 days and 1 year after surgery), long-term hearing results (PTA-ABG measured ≥5 years after surgery), and the rate of successful ABG closure to ≤20 dB. Secondary measures included the need for revision surgery, delayed tympanic membrane graft failure, worsening conductive hearing loss (after an initially satisfactory hearing result), and recurrence of cholesteatoma. There was no significant difference between adults and children for short-term hearing results (average post-op PTA-ABG was 18.9 dB vs. 19.8 dB, respectively; p = 0.544), long-term hearing results (average final PTA-ABG was 19.3 dB vs. 19.4 dB, respectively; p = 0.922), or rate of ABG closure to less than 20 dB (63.1% vs. 58.0%, p = 0.282). Spearman's rank-order correlation (ρ) identified a strong positive correlation between OOPS index score and average post-operative PTA-ABG (ρ = 0.983; p < 0.001; 2-tailed), as well as average long-term PTA-ABG (ρ = 0.950, p < 0.001; 2-tailed). The OOPS index makes it possible to accurately prognosticate hearing outcomes in adult and pediatric patients undergoing ossiculoplasty in both the short term and the long term.

Long Periodic Terms in the Solar System

NASA Technical Reports Server (NTRS)

Bretagnon, P.

1982-01-01

The long period variations of the first eight planets in the solar system are studied. First, the Lagrangian solution is calculated and then the long period terms with fourth order eccentricities and inclinations are introduced into the perturbation function. A second approximation was made taking into account the short period terms' contribution, namely the perturbations of first order with respect to the masses. Special attention was paid to the determination of the integration constants. The relative importance of the different contributions is shown. It is useless, for example, to introduce the long period terms of fifth order if no account has been taken of the short period terms. Meanwhile, the terms that have been neglected would not introduce large changes in the integration constants. Even so, the calculation should be repeated with higher order short period terms and fifth order long periods.

Short-term memory and long-term memory are still different.

PubMed

Norris, Dennis

2017-09-01

A commonly expressed view is that short-term memory (STM) is nothing more than activated long-term memory. If true, this would overturn a central tenet of cognitive psychology-the idea that there are functionally and neurobiologically distinct short- and long-term stores. Here I present an updated case for a separation between short- and long-term stores, focusing on the computational demands placed on any STM system. STM must support memory for previously unencountered information, the storage of multiple tokens of the same type, and variable binding. None of these can be achieved simply by activating long-term memory. For example, even a simple sequence of digits such as "1, 3, 1" where there are 2 tokens of the digit "1" cannot be stored in the correct order simply by activating the representations of the digits "1" and "3" in LTM. I also review recent neuroimaging data that has been presented as evidence that STM is activated LTM and show that these data are exactly what one would expect to see based on a conventional 2-store view. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Short-Term Memory and Long-Term Memory are Still Different

PubMed Central

2017-01-01

A commonly expressed view is that short-term memory (STM) is nothing more than activated long-term memory. If true, this would overturn a central tenet of cognitive psychology—the idea that there are functionally and neurobiologically distinct short- and long-term stores. Here I present an updated case for a separation between short- and long-term stores, focusing on the computational demands placed on any STM system. STM must support memory for previously unencountered information, the storage of multiple tokens of the same type, and variable binding. None of these can be achieved simply by activating long-term memory. For example, even a simple sequence of digits such as “1, 3, 1” where there are 2 tokens of the digit “1” cannot be stored in the correct order simply by activating the representations of the digits “1” and “3” in LTM. I also review recent neuroimaging data that has been presented as evidence that STM is activated LTM and show that these data are exactly what one would expect to see based on a conventional 2-store view. PMID:28530428

Long-term Follow-up of Psilocybin-facilitated Smoking Cessation

PubMed Central

Johnson, Matthew W.; Garcia-Romeu, Albert; Griffiths, Roland R.

2017-01-01

Background A recent open-label pilot study (N=15) found that two to three moderate to high doses (20 and 30 mg/70 kg) of the serotonin 2A receptor agonist psilocybin, in combination with cognitive behavioral therapy (CBT) for smoking cessation, resulted in substantially higher 6-month smoking abstinence rates than are typically observed with other medications or CBT alone. Objectives To assess long-term effects of a psilocybin-facilitated smoking cessation program at ≥12 months after psilocybin administration. Methods The present report describes biologically verified smoking abstinence outcomes of the previous pilot study at ≥12 months, and related data on subjective effects of psilocybin. Results All 15 participants completed a 12-month follow-up, and 12 (80%) returned for a long-term (≥16 months) follow-up, with a mean interval of 30 months (range = 16 – 57 months) between target-quit date (i.e., first psilocybin session) and long-term follow-up. At 12-month follow-up, 10 participants (67%) were confirmed as smoking abstinent. At long-term follow-up, nine participants (60%) were confirmed as smoking abstinent. At 12-month follow-up 13 participants (86.7%) rated their psilocybin experiences among the 5 most personally meaningful and spiritually significant experiences of their lives. Conclusion These results suggest that in the context of a structured treatment program, psilocybin holds considerable promise in promoting long-term smoking abstinence. The present study adds to recent and historical evidence suggesting high success rates when using classic psychedelics in the treatment of addiction. Further research investigating psilocybin-facilitated treatment of substance use disorders is warranted. PMID:27441452

The Spatiotemporal Structure of 20th Century Climate Variations in Observations and Reanalyses. Part 1; Long-term Trend

NASA Technical Reports Server (NTRS)

Chen, Junye; DelGenio, Anthony D.; Carlson, Barbara e.; Bosilovich, Michael G.

2007-01-01

The dominant interannual El Nino-Southern Oscillation phenomenon (ENSO) and the short length of climate observation records make it difficult to study long-term climate variations in the spatiotemporal domain. Based on the fact that the ENS0 signal spreads to remote regions and induces delayed climate variation through atmospheric teleconnections, we develop an ENSO-removal method through which the ENS0 signal can be approximately removed at the grid box level from the spatiotemporal field of a climate parameter. After this signal is removed, long-term climate variations, namely, the global warming trend (GW) and the Pacific pan-decadal variability (PDV), are isolated at middle and low latitudes in the climate parameter fields from observed and reanalyses datasets. Except for known GW characteristics, the warming that occurs in the Pacific basin (approximately 0.4K in the 2oth century) is much weaker than in surrounding regions and the other two ocean basins (approximately 0.8K). The modest warming in the Pacific basin is likely due to its dynamic nature on the interannual and decadal time scales and/or the leakage of upper ocean water through the Indonesian Throughflow. Based on NCEP/NCAR and ERA-40 reanalyses, a comprehensive atmospheric structure associated with GW is given. Significant discrepancies exist between the two datasets, especially in the tightly coupled dynamic and water vapor fields. The dynamic field based on NCEP/NCAR reanalysis, which shows a change in the Walker Circulation, is consistent with the GW change in the surface temperature field. However, intensification in the Hadley Circulation is associated with GW trend in the ERA-40 reanalysis.

Short-term and long-term plasticity interaction in human primary motor cortex.

PubMed

Iezzi, Ennio; Suppa, Antonio; Conte, Antonella; Li Voti, Pietro; Bologna, Matteo; Berardelli, Alfredo

2011-05-01

Repetitive transcranial magnetic stimulation (rTMS) over primary motor cortex (M1) elicits changes in motor evoked potential (MEP) size thought to reflect short- and long-term forms of synaptic plasticity, resembling short-term potentiation (STP) and long-term potentiation/depression (LTP/LTD) observed in animal experiments. We designed this study in healthy humans to investigate whether STP as elicited by 5-Hz rTMS interferes with LTP/LTD-like plasticity induced by intermittent and continuous theta-burst stimulation (iTBS and cTBS). The effects induced by 5-Hz rTMS and iTBS/cTBS were indexed as changes in MEP size. We separately evaluated changes induced by 5-Hz rTMS, iTBS and cTBS applied alone and those induced by iTBS and cTBS delivered after priming 5-Hz rTMS. Interactions between 5-Hz rTMS and iTBS/cTBS were investigated under several experimental conditions by delivering 5-Hz rTMS at suprathreshold and subthreshold intensity, allowing 1 and 5 min intervals to elapse between 5-Hz rTMS and TBS, and delivering one and ten 5-Hz rTMS trains. We also investigated whether 5-Hz rTMS induces changes in intracortical excitability tested with paired-pulse transcranial magnetic stimulation. When given alone, 5-Hz rTMS induced short-lasting and iTBS/cTBS induced long-lasting changes in MEP amplitudes. When M1 was primed with 10 suprathreshold 5-Hz rTMS trains at 1 min before iTBS or cTBS, the iTBS/cTBS-induced after-effects disappeared. The 5-Hz rTMS left intracortical excitability unchanged. We suggest that STP elicited by suprathreshold 5-Hz rTMS abolishes iTBS/cTBS-induced LTP/LTD-like plasticity through non-homeostatic metaplasticity mechanisms. Our study provides new information on interactions between short-term and long-term rTMS-induced plasticity in human M1. © 2011 The Authors. European Journal of Neuroscience © 2011 Federation of European Neuroscience Societies and Blackwell Publishing Ltd.

Long-Term Visual Training Increases Visual Acuity and Long-Term Monocular Deprivation Promotes Ocular Dominance Plasticity in Adult Standard Cage-Raised Mice

PubMed Central

Yusifov, Rashad

2018-01-01

Abstract For routine behavioral tasks, mice predominantly rely on olfactory cues and tactile information. In contrast, their visual capabilities appear rather restricted, raising the question whether they can improve if vision gets more behaviorally relevant. We therefore performed long-term training using the visual water task (VWT): adult standard cage (SC)-raised mice were trained to swim toward a rewarded grating stimulus so that using visual information avoided excessive swimming toward nonrewarded stimuli. Indeed, and in contrast to old mice raised in a generally enriched environment (Greifzu et al., 2016), long-term VWT training increased visual acuity (VA) on average by more than 30% to 0.82 cycles per degree (cyc/deg). In an individual animal, VA even increased to 1.49 cyc/deg, i.e., beyond the rat range of VAs. Since visual experience enhances the spatial frequency threshold of the optomotor (OPT) reflex of the open eye after monocular deprivation (MD), we also quantified monocular vision after VWT training. Monocular VA did not increase reliably, and eye reopening did not initiate a decline to pre-MD values as observed by optomotry; VA values rather increased by continued VWT training. Thus, optomotry and VWT measure different parameters of mouse spatial vision. Finally, we tested whether long-term MD induced ocular dominance (OD) plasticity in the visual cortex of adult [postnatal day (P)162–P182] SC-raised mice. This was indeed the case: 40–50 days of MD induced OD shifts toward the open eye in both VWT-trained and, surprisingly, also in age-matched mice without VWT training. These data indicate that (1) long-term VWT training increases adult mouse VA, and (2) long-term MD induces OD shifts also in adult SC-raised mice. PMID:29379877

Long-Term Visual Training Increases Visual Acuity and Long-Term Monocular Deprivation Promotes Ocular Dominance Plasticity in Adult Standard Cage-Raised Mice.

PubMed

Hosang, Leon; Yusifov, Rashad; Löwel, Siegrid

2018-01-01

For routine behavioral tasks, mice predominantly rely on olfactory cues and tactile information. In contrast, their visual capabilities appear rather restricted, raising the question whether they can improve if vision gets more behaviorally relevant. We therefore performed long-term training using the visual water task (VWT): adult standard cage (SC)-raised mice were trained to swim toward a rewarded grating stimulus so that using visual information avoided excessive swimming toward nonrewarded stimuli. Indeed, and in contrast to old mice raised in a generally enriched environment (Greifzu et al., 2016), long-term VWT training increased visual acuity (VA) on average by more than 30% to 0.82 cycles per degree (cyc/deg). In an individual animal, VA even increased to 1.49 cyc/deg, i.e., beyond the rat range of VAs. Since visual experience enhances the spatial frequency threshold of the optomotor (OPT) reflex of the open eye after monocular deprivation (MD), we also quantified monocular vision after VWT training. Monocular VA did not increase reliably, and eye reopening did not initiate a decline to pre-MD values as observed by optomotry; VA values rather increased by continued VWT training. Thus, optomotry and VWT measure different parameters of mouse spatial vision. Finally, we tested whether long-term MD induced ocular dominance (OD) plasticity in the visual cortex of adult [postnatal day (P)162-P182] SC-raised mice. This was indeed the case: 40-50 days of MD induced OD shifts toward the open eye in both VWT-trained and, surprisingly, also in age-matched mice without VWT training. These data indicate that (1) long-term VWT training increases adult mouse VA, and (2) long-term MD induces OD shifts also in adult SC-raised mice.

Educational network comparative analysis of small groups: Short- and long-term communications

NASA Astrophysics Data System (ADS)

Berg, D. B.; Zvereva, O. M.; Nazarova, Yu. Yu.; Chepurov, E. G.; Kokovin, A. V.; Ranyuk, S. V.

2017-11-01

The present study is devoted to the discussion of small group communication network structures. These communications were observed in student groups, where actors were united with a regular educational activity. The comparative analysis was carried out for networks of short-term (1 hour) and long-term (4 weeks) communications, it was based on seven structural parameters, and consisted of two stages. At the first stage, differences between the network graphs were examined, and the random corresponding Bernoulli graphs were built. At the second stage, revealed differences were compared. Calculations were performed using UCINET software framework. It was found out that networks of long-term and short-term communications are quite different: the structure of a short-term communication network is close to a random one, whereas the most of long-term communication network parameters differ from the corresponding random ones by more than 30%. This difference can be explained by strong "noisiness" of a short-term communication network, and the lack of social in it.

R Aqr observing campaign

NASA Astrophysics Data System (ADS)

Waagen, Elizabeth O.

2016-01-01

Dr. George Wallerstein (University of Washington) has requested AAVSO coverage of the long period/symbiotic variable R Aquarii beginning immediately in support of high resolution spectroscopic observations planned for 2016 January 19 and 21. Several other astronomers, including Drs. Lee Anne Willson (Iowa State University), Ulisse Munari (INAF, Astronomical Observatory of Padua, Italy), and Fred Walter (Stony Brook University) are studying R Aqr closely and additional spectroscopic and other observations are planned for the near future. R Aqr is both a Mira (M) and a symbiotic (ZAND) - it is a close binary system consisting of a hot star and a late-type star (the Mira), both enveloped in nebulosity. As a result, the very interesting light curve shows not only the Mira pulsation but also complex eclipse behavior as the two stars interact. The period of Mira variation is 387.0 days; the eclipse period is 43.6-44 years. The cause of the eclipse is unknown; several theories h! ave been proposed, including a focused accretion stream, a disk or cloud around the secondary, and a triggered mass loss that produces an opaque cloud. Careful investigation of this upcoming event should help to resolve this question. The last eclipse of R Aqr was in 1978. The next eclipse is predicted for 2022, but may be early. The current behavior of R Aqr suggests that the eclipse, which lasts for several years, may either be beginning or its beginning may be imminent. R Aqr was at minimum in early December 2015 at magnitude V=11.4, and is currently at visual magnitude 11.0. During this phase of the approximately 44-year eclipse cycle, at maximum it may be as bright as V 6.0-6.5 but is not expected to become brighter. Beginning immediately, nightly BVRI CCD and DSLR photometry and visual observations are requested. As R Aqr brightens towards maximum and is in range, PEP observations are also requested. Ongoing spectroscopy over the next several years will be interesting to see as the system

Dignity in long-term care: An application of Nordenfelt's work.

PubMed

Kane, Jennifer; de Vries, Kay

2017-09-01

The concept of dignity is recognised as a fundamental right in many countries. It is embedded into law, human rights legislation and is often visible in organisations' philosophy of care, particularly in aged care. Yet, many authors describe difficulties in defining dignity and how it can be preserved for people living in long term care. In this article, Nordenfelt's 'four notions of dignity' are considered, drawing on research literature addressing the different perspectives of those who receive, observe or deliver care in the context of the long-term care environment. A review of the literature was undertaken using the terms 'nursing homes', 'residential care' or 'long-term care'. The terms were combined and the term 'human dignity' was added. A total of 29 articles met the inclusion criteria from the United Kingdom (14), United States (2), Australia (1), Sweden (3), Hong Kong (2), Norway (3), Nordic (1), Taiwan (1), Netherlands (1). Ethical Considerations: Every effort has been made to ensure an unbiased search of the literature with the intention of an accurate interpretation of findings. The four notions of dignity outlined by Nordenfelt provide a comprehensive description of the concept of dignity which can be linked to the experiences of people living in long-term care today and provide a useful means of contextualising the experiences of older people, their families and significant others and also of staff in long-term care facilities. Of particular interest are the similarities of perspectives of dignity between these groups. The preservation of dignity implies that dignity is a quality inherent in us all. This links directly to the exploration and conclusions drawn from the literature review. Conversely, promoting dignity implies that dignity is something that can be influenced by others and external factors. Hence, there are a number of implications for practice. We suggest that two of Nordenfelt's notions, 'dignity of identity' and 'dignity of Menschenw

Long-term follow-up observation of the safety, immunogenicity, and effectiveness of Gardasil™ in adult women.

PubMed

Luna, Joaquin; Plata, Manuel; Gonzalez, Mauricio; Correa, Alfonso; Maldonado, Ivete; Nossa, Claudia; Radley, David; Vuocolo, Scott; Haupt, Richard M; Saah, Alfred

2013-01-01

Previous analyses from a randomized trial in women aged 24-45 have shown the quadrivalent HPV vaccine to be efficacious in the prevention of infection, cervical intraepithelial neoplasia (CIN) and external genital lesions (EGL) related to HPV 6/11/16/18 through 4 years. In this report we present long term follow-up data on the efficacy, safety and immunogenicity of the quadrivalent HPV vaccine in adult women. Follow-up data are from a study being conducted in 5 sites in Colombia designed to evaluate the long-term immunogenicity, effectiveness, and safety of the qHPV vaccine in women who were vaccinated at 24 to 45 years of age (in the original vaccine group during the base study [n = 684]) or 29 to 50 years of age (in the original placebo group during the base study [n = 651]). This analysis summarizes data collected as of the year 6 post-vaccination visit relative to day 1 of the base study (median follow-up of 6.26 years) from both the original base study and the Colombian follow-up. There were no cases of HPV 6/11/16/18-related CIN or EGL during the extended follow-up phase in the per-protocol population. Immunogenicity persists against vaccine-related HPV types, and no evidence of HPV type replacement has been observed. No new serious adverse experiences have been reported. Vaccination with qHPV vaccine provides generally safe and effective protection from HPV 6-, 11-, 16-, and 18-related genital warts and cervical dysplasia through 6 years following administration to 24-45 year-old women. Clinicaltrials.govNCT00090220.

Long-Term Follow-up Observation of the Safety, Immunogenicity, and Effectiveness of Gardasil™ in Adult Women

PubMed Central

Luna, Joaquin; Plata, Manuel; Gonzalez, Mauricio; Correa, Alfonso; Maldonado, Ivete; Nossa, Claudia; Radley, David; Vuocolo, Scott; Haupt, Richard M.; Saah, Alfred

2013-01-01

Background Previous analyses from a randomized trial in women aged 24–45 have shown the quadrivalent HPV vaccine to be efficacious in the prevention of infection, cervical intraepithelial neoplasia (CIN) and external genital lesions (EGL) related to HPV 6/11/16/18 through 4 years. In this report we present long term follow-up data on the efficacy, safety and immunogenicity of the quadrivalent HPV vaccine in adult women. Methods Follow-up data are from a study being conducted in 5 sites in Colombia designed to evaluate the long-term immunogenicity, effectiveness, and safety of the qHPV vaccine in women who were vaccinated at 24 to 45 years of age (in the original vaccine group during the base study [n = 684]) or 29 to 50 years of age (in the original placebo group during the base study [n = 651]). This analysis summarizes data collected as of the year 6 post-vaccination visit relative to day 1 of the base study (median follow-up of 6.26 years) from both the original base study and the Colombian follow-up. Results There were no cases of HPV 6/11/16/18-related CIN or EGL during the extended follow-up phase in the per-protocol population. Immunogenicity persists against vaccine-related HPV types, and no evidence of HPV type replacement has been observed. No new serious adverse experiences have been reported. Conclusions Vaccination with qHPV vaccine provides generally safe and effective protection from HPV 6-, 11-, 16-, and 18-related genital warts and cervical dysplasia through 6 years following administration to 24–45 year-old women. Trial Registration Clinicaltrials.gov NCT00090220 PMID:24391768

Estimating Causal Effects from Family Planning Health Communication Campaigns Using Panel Data: The “Your Health, Your Wealth” Campaign in Egypt

PubMed Central

Hutchinson, Paul L.; Meekers, Dominique

2012-01-01

Background Health communication campaigns – involving mass media and interpersonal communication - have long been utilized by national family planning programs to create awareness about contraceptive methods, to shift social norms related to fertility control, and to promote specific behaviors, such as the use of condoms, injectable methods or permanent sterilization. However, demonstrating the effectiveness of these campaigns is often complicated because the infeasibility of experimental designs generally yields statistically non-equivalent samples of campaign-exposed and unexposed individuals. Methods Using data from a panel survey of reproductive age women in Egypt, we estimate the effects of the multimedia health communication campaign “Your Health, Your Wealth” (“Sahatek Sarwetek”) on precursors to contraceptive use (e.g., spousal communication, birth spacing attitudes) and on modern contraceptive use. Difference-in-differences and fixed effects estimators that exploit the panel nature of the data are employed to control for both observed and unobserved heterogeneity in the sample of women who self-report recall of the messages, thereby potentially improving upon methods that make no such controls or that rely solely on cross-sectional data. Findings All of the estimators find positive effects of the “Your Health, Your Wealth” campaign on reproductive health outcomes, though the magnitudes of those effects diverge, often considerably. Difference-in-differences estimators find that exposure to the campaign increases the likelihood of spousal discussions by 14.4 percentage points (pp.) (SE = .039, p<0.001) but has no effect on contraceptive use. In contrast, the fixed effects, instrumental variables estimator, controlling for unobserved heterogeneity, finds a large, statistically significant effect on modern contraceptive use (27.4 pp., SE = 0.135, p = 0.043). Conclusions The difficulties of evaluating family planning communication

Long-term variations of the UV-B radiation over Central Europe since early 1960s, as revealed from the UV observations and reconstructed data

NASA Astrophysics Data System (ADS)

Krzyscin, J. W.

2003-04-01

A method of reconstruction of the UV variations for periods when UV-B measurements were not carried out is proposed. The reconstruction is based on observations of total (Sun+sky) radiation by a pyranometer, Dobson total ozone, sunshine duriation from the Campbel Stokes heliograph, and atmospheric column water content taken from NCEP/NOAA reanalysis. Modeled all-sky erythemaly weighted daily dose is calculated as a product of the cloud reduction factor (CRF) over UV range and clear-sky dose from a radiative transfer model. CRF over UV range is estimated from measured CRF for total solar radiation and the statistical dependence relating CRF over UV with that over whole solar spectrum. The measured daily UV doses and daily sum of total radiation taken at Belsk, Poland (52N, 21E) for the period 1976-2001 have been used to construct the regressions for various solar zenith angles. The time series of monthly means from the modeled daily UV doses follows the observed monthly means supporting the possibility of reconstruction of the UV time series for other periods. An inspection of the long-term stability of total radiation measurements is necessary to discuss trends in the reconstructed time series. We examine the data homogeneity analyzing the ratio of the observed to modeled total radiation for fully clear sky days that are selected from the daily values of sunshine duration measured by the Campbel-Stokes heliograph. Combining reconstructed and observed monthly means of the UV doses we found a positive trend in the UV radiation in the period 1980-1995 and almost constant UV level for other periods (early 60s up to 1980, and 1995-2001). The trend pattern suggests dominating role of the long-term total ozone forcing on the UV level with a small impact of the long-term changes in the cloud/aerosol properties.

Virtual Models of Long-Term Care

ERIC Educational Resources Information Center

Phenice, Lillian A.; Griffore, Robert J.

2012-01-01

Nursing homes, assisted living facilities and home-care organizations, use web sites to describe their services to potential consumers. This virtual ethnographic study developed models representing how potential consumers may understand this information using data from web sites of 69 long-term-care providers. The content of long-term-care web…

Natural history of diminutive colorectal polyps: long-term prospective observation by colonoscopy.

PubMed

Mizuno, Ken-Ichi; Suzuki, Yutaka; Takeuchi, Manabu; Kobayashi, Masaaki; Aoyagi, Yutaka

2014-04-01

Endoscopic removal of colorectal adenomatous polyps effectively prevents cancer. However, the treatment strategy for diminutive polyps (diameter ≤ 5 mm) remains controversial. Understanding the natural history of diminutive polyps is a prerequisite to their effective management. We prospectively examined the natural history of diminutive polyps by long-term surveillance colonoscopy. A total of 207 polyps detected in 112 patients from December 1991 through March 2002 were studied. To avoid potential effects on size and morphological characteristics, all polyps were selected randomly and were followed without biopsy. Polyp size was estimated by comparing the lesion with the diameter of a biopsy forceps. Mean follow up was 7.8 years (SD, 4.8; range, 1.0-18.6; median, 7.5; interquartile range 3.4-11.2). Twenty-four polyps were resected endoscopically, and the histopathological diagnosis was mucosal high-grade neoplasia (Category 4) for one polyp, and mucosal low-grade neoplasia (Category 3) for 23 polyps. Mean linear size of the polyps was 3.2 mm (SD, 1.0; range, 1.3-5.0) at initial colonoscopy and 3.8 mm (SD 1.6; range 1.3-10.0) at final colonoscopy (P<0.01). Left-sided polyps showed a higher growth rate than right-sided polyps, and a type IIIL2 pit pattern was associated with a lower growth rate than a type IIIL1 pattern. We clarified the natural history of diminutive polyps by long-term follow-up colonoscopy. The benign course of diminutive polyps should be considered in the design of treatment strategies. © 2014 The Authors. Digestive Endoscopy © 2014 Japan Gastroenterological Endoscopy Society.

Development of mobile sensor for volcanic observation "HOMURA": Test campaign at Kirishima Iwo-yama, SW Japan

NASA Astrophysics Data System (ADS)

Kaneko, K.; Ito, K.; Iwahori, K.; Anbe, Y.

2015-12-01

Monitoring volcanoes near active craters is important to know symptoms and transitions of volcanic eruptions. In order to observe volcanic phenomena near craters according to the circumstance, monitoring system with unmanned robots are useful. We have been trying to develop a practical UGV-type robot, and have completed a prototype, which we named "Homura". Homura is a small-sized, vehicle-type robot with six wheels (750 x 430 x 310 mm in dimensions and a weight of about 12 kg). Homura is remotely controlled with mobile phone radio waves; it can move in volcanic fields and send real time data of sensors equipped in the vehicle to the base station. We carried out a test campaign of Homura from Feb. 19th to Apr. 8th, 2015 at Iwo-yama to examine if Homura can work for a few month in natural volcanic fields. Iwo-yama is one of craters in the Kirishima volcanic field, SW Japan; the area within 1 km from the crater was an off-limit area from Oct. 24th, 2014 to May 5th, 2015 because volcanic seismicity there was active and eruption might occur. On Feb. 19th, we carried and put Homura at the rim of the crater. Unfortunately, mobile phone connectivity was not entirely stable around Iwo-yama. Then, we decided not to move Homura and only to obtain real time data of the sensors (a camera, CO2 gas sensor, and thermometer). After we returned to our office, we operated Homura for one to two hours every day until Apr. 8th. Although the weather was often bad (rain, fog, or cold temperature) during the test campaign, we could completely operate Homura without any trouble. On Apr. 8th, the battery in Homura ran down. After we collected Homura from Iwo-yama and recharged the battery, Homura perfectly worked again. The results of this campaign indicate that Homura stably operates for a long time in volcanic field. Homura is useful as simple monitoring station in volcanic fields where mobile phone connection is available.

The long-term use of cyproterone acetate in pedophilia: a case study.

PubMed

Cooper, A J; Cernovsky, Z; Magnus, R V

1992-01-01

This investigation reports the long-term use of the antiandrogen cyproterone acetate (CPA) in a pedophile, who was studied continuously over 38 months. Measures of sexual arousal, serum testosterone, and gonadotropin levels were significantly reduced by the drug as compared with placebo and no treatment; prolactin levels were significantly elevated. Some workers have observed that long-term administration of CPA (more than one year, which was then discontinued) produced enduring (in some cases apparently permanent) anti-libidinal effects; however, in the case described, within three weeks of stopping the drug, all measures had returned to pretrial levels. The importance of continuous long-term monitoring in sex offenders receiving an antiandrogen is discussed.

Prevalence of Long-Term Opioid Use in Long-Stay Nursing Home Residents.

PubMed

Hunnicutt, Jacob N; Chrysanthopoulou, Stavroula A; Ulbricht, Christine M; Hume, Anne L; Tjia, Jennifer; Lapane, Kate L

2018-01-01

Overall and long-term opioid use among older adults have increased since 1999. Less is known about opioid use in older adults in nursing homes (NHs). Cross-sectional. U.S. NHs (N = 13,522). Long-stay NH resident Medicare beneficiaries with a Minimum Data Set 3.0 (MDS) assessment between April 1, 2012, and June 30, 2012, and 120 days of follow-up (N = 315,949). We used Medicare Part D claims to measure length of opioid use in the 120 days from the index assessment (short-term: ≤30 days, medium-term: >30-89 days, long-term: ≥90 days), adjuvants (e.g., anticonvulsants), and other pain medications (e.g., corticosteroids). MDS assessments in the follow-up period were used to measure nonpharmacological pain management use. Modified Poisson models were used to estimate adjusted prevalence ratios (aPR) and 95% confidence intervals (CI) for age, gender, race and ethnicity, cognitive and physical impairment, and long-term opioid use. Of all long-stay residents, 32.4% were prescribed any opioid, and 15.5% were prescribed opioids long-term. Opioid users (versus nonusers) were more commonly prescribed pain adjuvants (32.9% vs 14.9%), other pain medications (25.5% vs 11.0%), and nonpharmacological pain management (24.5% vs 9.3%). Long-term opioid use was higher in women (aPR = 1.21, 95% CI = 1.18-1.23) and lower in racial and ethnic minorities (non-Hispanic blacks vs whites: APR = 0.93, 95% CI = 0.90-0.94) and those with severe cognitive impairment (vs no or mild impairment, aPR = 0.82, 95% CI = 0.79-0.83). One in seven NH residents was prescribed opioids long-term. Recent guidelines on opioid prescribing for pain recommend reducing long-term opioid use, but this is challenging in NHs because residents may not benefit from nonpharmacological and nonopioid interventions. Studies to address concerns about opioid safety and effectiveness (e.g., on pain and functional status) in NHs are needed. © 2017, Copyright the Authors Journal compilation © 2017, The American Geriatrics

Planning long lasting insecticide treated net campaigns: should households’ existing nets be taken into account?

PubMed Central

2013-01-01

Background Mass distribution of long-lasting insecticide treated bed nets (LLINs) has led to large increases in LLIN coverage in many African countries. As LLIN ownership levels increase, planners of future mass distributions face the challenge of deciding whether to ignore the nets already owned by households or to take these into account and attempt to target individuals or households without nets. Taking existing nets into account would reduce commodity costs but require more sophisticated, and potentially more costly, distribution procedures. The decision may also have implications for the average age of nets in use and therefore on the maintenance of universal LLIN coverage over time. Methods A stochastic simulation model based on the NetCALC algorithm was used to determine the scenarios under which it would be cost saving to take existing nets into account, and the potential effects of doing so on the age profile of LLINs owned. The model accounted for variability in timing of distributions, concomitant use of continuous distribution systems, population growth, sampling error in pre-campaign coverage surveys, variable net ‘decay’ parameters and other factors including the feasibility and accuracy of identifying existing nets in the field. Results Results indicate that (i) where pre-campaign coverage is around 40% (of households owning at least 1 LLIN), accounting for existing nets in the campaign will have little effect on the mean age of the net population and (ii) even at pre-campaign coverage levels above 40%, an approach that reduces LLIN distribution requirements by taking existing nets into account may have only a small chance of being cost-saving overall, depending largely on the feasibility of identifying nets in the field. Based on existing literature the epidemiological implications of such a strategy is likely to vary by transmission setting, and the risks of leaving older nets in the field when accounting for existing nets must be considered

Planning long lasting insecticide treated net campaigns: should households' existing nets be taken into account?

PubMed

Yukich, Joshua; Bennett, Adam; Keating, Joseph; Yukich, Rudy K; Lynch, Matt; Eisele, Thomas P; Kolaczinski, Kate

2013-06-14

Mass distribution of long-lasting insecticide treated bed nets (LLINs) has led to large increases in LLIN coverage in many African countries. As LLIN ownership levels increase, planners of future mass distributions face the challenge of deciding whether to ignore the nets already owned by households or to take these into account and attempt to target individuals or households without nets. Taking existing nets into account would reduce commodity costs but require more sophisticated, and potentially more costly, distribution procedures. The decision may also have implications for the average age of nets in use and therefore on the maintenance of universal LLIN coverage over time. A stochastic simulation model based on the NetCALC algorithm was used to determine the scenarios under which it would be cost saving to take existing nets into account, and the potential effects of doing so on the age profile of LLINs owned. The model accounted for variability in timing of distributions, concomitant use of continuous distribution systems, population growth, sampling error in pre-campaign coverage surveys, variable net 'decay' parameters and other factors including the feasibility and accuracy of identifying existing nets in the field. Results indicate that (i) where pre-campaign coverage is around 40% (of households owning at least 1 LLIN), accounting for existing nets in the campaign will have little effect on the mean age of the net population and (ii) even at pre-campaign coverage levels above 40%, an approach that reduces LLIN distribution requirements by taking existing nets into account may have only a small chance of being cost-saving overall, depending largely on the feasibility of identifying nets in the field. Based on existing literature the epidemiological implications of such a strategy is likely to vary by transmission setting, and the risks of leaving older nets in the field when accounting for existing nets must be considered. Where pre-campaign coverage

Long-term Lake Evaporation Measurements in Southeastern Brazil

NASA Astrophysics Data System (ADS)

Dias, N. L.; Cancelli, D. M.

2007-05-01

We report here for the first time the results of a long-term (37 months) campaign of lake evaporation measurements with the eddy-covariance (EC) method. The measurements were made at Furnas Lake, a large lake (1440 km2) in Southeastern Brazil (20° 44'S, 45° 58'W and 771.8 m ASL). Mean and maximum depths at the Maximum Normal Operating Level are 13 m and 90 m respectively. Taking advantage of a long drought during 2000--2001, a large metal tower was erected over the lake's dry bed. After the water level recovered, we were left with a stable platform for performing EC measurements in one of the lake's many basins. Fetch conditions over the prevailing wind directions were excellent (1000 m from the North, and more than 3000 m from the East), with the closest land at 420 m (from NE) and 440 m (from SW). Measurements included hourly means of water surface temperature, air temperature, specific humidity, downwelling solar radiation, net radiation, wind speed, and wind direction. 10-Hz eddy covariance measurements were made of turbulent fluctuations of 3 wind components, sonic virtual temperature, air temperature (with a fine-wire thermocouple) and of fluctuating specific humidity with a specially adapted capacitive hygrometer. The validation of this sensor to measure latent heat fluxes at high frequency was made on intensive field campaigns that deployed state-of-the art Ultra-Violet and Infra-Red fast-response hygrometers. Our data analysis indicates that atmospheric stability can be far from neutral, and that it plays a very important role in the mass-transfer and heat-transfer equations for the water vapor and sensible heat fluxes. We have also found that significantly different scalar roughenesses for water vapor and for sensible heat were necessary to calibrate properly the Monin-Obukhov Similarity Theory (MOST)-based transfer equations. Due to these differences, gradient-based Bowen ratios (as usually applied in the Energy Budget Bowen Ratio method in the absence

Memory Reactivation Enables Long-Term Prevention of Interference.

PubMed

Herszage, Jasmine; Censor, Nitzan

2017-05-22

The ability of the human brain to successively learn or perform two competing tasks constitutes a major challenge in daily function. Indeed, exposing the brain to two different competing memories within a short temporal offset can induce interference, resulting in deteriorated performance in at least one of the learned memories [1-4]. Although previous studies have investigated online interference and its effects on performance [5-13], whether the human brain can enable long-term prevention of future interference is unknown. To address this question, we utilized the memory reactivation-reconsolidation framework [2, 12] stemming from studies at the synaptic level [14-17], according to which reactivation of a memory enables its update. In a set of experiments, using the motor sequence learning task [18] we report that a unique pairing of reactivating the original memory (right hand) in synchrony with novel memory trials (left hand) prevented future interference between the two memories. Strikingly, these effects were long-term and observed a month following reactivation. Further experiments showed that preventing future interference was not due to practice per se, but rather specifically depended on a limited time window induced by reactivation of the original memory. These results suggest a mechanism according to which memory reactivation enables long-term prevention of interference, possibly by creating an updated memory trace integrating original and novel memories during the reconsolidation time window. The opportunity to induce a long-term preventive effect on memories may enable the utilization of strategies optimizing normal human learning, as well as recovery following neurological insults. Copyright © 2017 Elsevier Ltd. All rights reserved.

Complex network structure influences processing in long-term and short-term memory.

PubMed

Vitevitch, Michael S; Chan, Kit Ying; Roodenrys, Steven

2012-07-01

Complex networks describe how entities in systems interact; the structure of such networks is argued to influence processing. One measure of network structure, clustering coefficient, C, measures the extent to which neighbors of a node are also neighbors of each other. Previous psycholinguistic experiments found that the C of phonological word-forms influenced retrieval from the mental lexicon (that portion of long-term memory dedicated to language) during the on-line recognition and production of spoken words. In the present study we examined how network structure influences other retrieval processes in long- and short-term memory. In a false-memory task-examining long-term memory-participants falsely recognized more words with low- than high-C. In a recognition memory task-examining veridical memories in long-term memory-participants correctly recognized more words with low- than high-C. However, participants in a serial recall task-examining redintegration in short-term memory-recalled lists comprised of high-C words more accurately than lists comprised of low-C words. These results demonstrate that network structure influences cognitive processes associated with several forms of memory including lexical, long-term, and short-term.

Observations and Modeling of the Green Ocean Amazon: Sounding Enhancement Field Campaign Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schumacher, Courtney

2016-05-01

The goal of this campaign was to provide higher temporal sampling of the vertical structure of the atmosphere during the two intensive observational periods (IOPs) of the GoAmazon 2014/15 campaign. The U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Climate Research Facility’s first ARM Mobile Facility (AMF1) baseline launches for 2014 and 2015 was 4 sondes/day at 2 am, 8 am, 2 pm, and 8 pm local time (LT) (6, 12, 18 and 0 Coordinated Universal Time [UTC]). However, rapid changes in boundary layer and free tropospheric temperature, humidity, and wind profiles happen throughout the diurnal cycle over Manaus,more » Brazil's complex forest canopy with resulting responses in aerosol, cloud, and precipitation characteristics. This campaign increased sampling to 5 sondes/day for the 2014 wet and dry season IOPs by adding a launch at 11 am (15 UTC) to capture rapid changes in boundary layer properties and convective cloud growth during that time. The extra launch also corresponded to the time of day the ARM Gulfstream (G-1) and German HALO aircraft most often flew, thus providing useful measurements of the large-scale environment during the flights. In addition, the extra launch will significantly add to the quality of AMF1 instrument retrievals and variational analysis forcing data set during the IOPs.« less

Long-term outcomes of acute kidney injury.

PubMed

Coca, Steven G

2010-05-01

The goal of this review is to summarize the recent plethora of data that relate to long-term outcomes after acute kidney injury (AKI). Surviving patients with AKI are still at high risk for long-term adverse outcomes, even if serum creatinine returns to normal. After adjusting for potential confounders, many recent studies have demonstrated that AKI is independently associated with chronic kidney disease, end-stage renal disease, and premature death. Unfortunately, definitive evidence from randomized controlled trials demonstrating that prevention or treatment of AKI prevents long-term adverse outcomes is not yet available. AKI is clearly a prognostic marker for poor long-term outcomes, but more studies will be needed to determine whether AKI is truly causal and whether or not the risk is modifiable.

An analysis of the effects of a campaign supporting use of a health symbol on food sales and shopping behaviour of consumers.

PubMed

Mørk, Trine; Grunert, Klaus G; Fenger, Morten; Juhl, Hans Jørn; Tsalis, George

2017-03-09

Since 2009, the green Keyhole symbol has been a joint Nordic initiative for signalling healthfulness of specific food products. In 2014, the Danish Ministry of Food, Agriculture and Fisheries carried out a campaign aimed mainly at men over 35 with a low level of education, encouraging them to use the Keyhole in their shopping process. The objective of the study is to evaluate the campaign by measuring its effect on consumer behaviour in the store. The impact of the Keyhole campaign was measured in selected retail stores. Sales data were analysed to ascertain whether sales of Keyhole labelled products changed during and after the campaign. Observations and interviews were conducted in the same stores. The campaign had a positive effect on sales of Keyhole-labelled products in two out of three retail chains investigated. In these two retail chains, sales of Keyhole labelled products rose by about 20%. In the third chain, there was a slight decrease of sales of Keyhole labelled products. The effect differed considerably between product categories. Analysis of the interview data indicated that by the end of the campaign, shoppers with a short education had a higher likelihood of mentioning health as a purchase motive, and there was a higher general tendency to look for nutrition information. Results suggest that the campaign did have effects on shopper behaviour and that it is possible to address shoppers with a short education by a tailored campaign. However, long-term effect of the campaign was not ascertained.

Statistical analysis of Brazilian electoral campaigns via Benford's law

NASA Astrophysics Data System (ADS)

Gamermann, Daniel; Antunes, Felipe Leite

2018-04-01

The principle of democracy is that the people govern through elected representatives. Therefore, a democracy is healthy as long as the elected politicians do represent the people. We have analyzed data from the Brazilian electoral court (Tribunal Superior Eleitoral, TSE) concerning money donations for the electoral campaigns and the election results. Our work points to two conclusions that combined may be in conflict with the democratic principle: money is the determining factor on whether a candidate is elected or not (opposed to representativeness); secondly, the use of Benford's Law to analyze the declared donations received by the parties and electoral campaigns shows either possible manipulations in the declarations or a significant number of donations that might not have been spontaneous from the donors. The better term that describes Brazil's government system is plutocracy (govern by the wealthy).

Long term landslide monitoring with Ground Based SAR

NASA Astrophysics Data System (ADS)

Monserrat, Oriol; Crosetto, Michele; Luzi, Guido; Gili, Josep; Moya, Jose; Corominas, Jordi

2014-05-01

In the last decade, Ground-Based (GBSAR) has proven to be a reliable microwave Remote Sensing technique in several application fields, especially for unstable slopes monitoring. GBSAR can provide displacement measurements over few squared kilometres areas and with a very high spatial and temporal resolution. This work is focused on the use of GBSAR technique for long term landslide monitoring based on a particular data acquisition configuration, which is called discontinuous GBSAR (D-GBSAR). In the most commonly used GBSAR configuration, the radar is left installed in situ, acquiring data periodically, e.g. every few minutes. Deformations are estimated by processing sets of GBSAR images acquired during several weeks or months, without moving the system. By contrast, in the D-GBSAR the radar is installed and dismounted at each measurement campaign, revisiting a given site periodically. This configuration is useful to monitor slow deformation phenomena. In this work, two alternative ways for exploiting the D-GBSAR technique will be presented: the DInSAR technique and the Amplitude based Technique. The former is based on the exploitation of the phase component of the acquired SAR images and it allows providing millimetric precision on the deformation estimates. However, this technique presents several limitations like the reduction of measurable points with an increase in the period of observation, the ambiguous nature of the phase measurements, and the influence of the atmospheric phase component that can make it non applicable in some cases, specially when working in natural environments. The second approach, that is based on the use of the amplitude component of GB-SAR images combined with a image matching technique, will allow the estimation of the displacements over specific targets avoiding two of the limitations commented above: the phase unwrapping and atmosphere contribution but reducing the deformation measurement precision. Two successful examples of D

Developing a Mass Media Campaign to Promote Mammography Awareness in African American Women in the Nation's Capital.

PubMed

Wallington, Sherrie Flynt; Oppong, Bridget; Iddirisu, Marquita; Adams-Campbell, Lucile L

2017-12-26

This study developed and examined the reach and impact of a culturally appropriate mass media campaign pilot, designed to increase awareness about the importance of mammography screening and the available community mammography services for low-income African American women ages 40 and above. We conducted formative research using focus groups to inform campaign development, resulting in five emergent themes-good breast health, holistic views of healthiness, cancer fatalism, fear of mammogram machines, and mammogram affordability. The campaign targeted specific low-income African American communities in the District of Columbia via print ads in Metro stations and on buses, print ads in the Washington Informer, and online ads on a local TV network website. Data were collected before, during, and after campaign implementation to assess reach and impact. Reach was measured by number of impressions (number of people exposed to the campaign), while impact was assessed via online ad click-through rates, website use and referrals, and mammography center calls. The campaign was successful in reaching the target audience, with a total combined reach from all media of 9,479,386 impressions. In addition, the mammography center received significant increases in new website visitors (1482 during the campaign, compared to 24 during the preceding period) as well as 97 calls to the dedicated phone line. Further research involving a more long-term investment in terms of funding and campaign run time, coupled with a more robust evaluation, is needed to assess if culturally appropriate mass media campaigns can generate increased mammography screening rates and decrease breast-cancer-related mortality.

Coronal magnetic structures observing campaign. I - Simultaneous microwave and soft X-ray observations of active regions at the solar limb

NASA Astrophysics Data System (ADS)

Nitta, N.; White, S. M.; Kundu, M. R.; Gopalswamy, N.; Holman, G. D.; Brosius, J. W.; Schmelz, J. T.; Saba, J. L. R.; Strong, K. T.

1991-06-01

Using simultaneous microwave and soft X-ray measurements made with the Very Large Array (VLA) at 6 and 20 cm and the X-ray Polychromator (XRP) aboard the Solar Maximum Mission (SMM), we have studied two active regions near the solar limb. These observations were taken as part of the Coronal Magnetic Structures Observing Campaign (CoMStOC), a collaboration designed to study the magnetic field in the solar corona. The images in soft X-rays and at 20 cm wavelength are similar: both show peaks above the active regions and extended bridge of emission 200,000 km long connecting the two regions. The brightness temperature of the 20 cm emission is lower than that predicted from the X-ray emitting material, however; it can be attributed to free-free emission in cooler (<106 K) plasma not visible to XRP, with an optical depth ˜1. The 6 cm emission is concentrated at lower altitudes and in a ˜160,000 km long bundle of loops in the northern active region. Comparison of the 6 cm map with the potential magnetic field lines computed from photospheric magnetic fields (measured 2 days earlier) indicates that the 6 cm emission is associated with fields of less than ˜200 G. Such fields would be too weak to attribute the observed 6 cm emission to gyroresonance radiation. Analysis of the 6 cm loop bundle indicates that it is strongly asymmetric, with the magnetic field in the northern leg ˜2 times stronger than in the southern leg; the 6 cm emission most likely arises from a combination of hot ( ≥ 2 × 106 K) and cool plasmas, while the 20 cm emission becomes optically thick in the cooler (˜9 × 103 K) plasma. We estimate an Alfvén speed ˜7000 km s-1 and ratio of electron gyrofrequency to plasma frequency ˜1.0 in the northern leg of the 6 cm loop.

Dysglycemia and long-term mortality: observations from the Israel study of glucose intolerance, obesity and hypertension.

PubMed

Bergman, Michael; Chetrit, Angela; Roth, Jesse; Dankner, Rachel

2015-05-01

We describe the relationship between dysglycemia and long-term mortality and elucidate the relationship between blood glucose levels during an oral glucose tolerance test (OGTT) and haemoglobin A1 (HbA1) and mortality. A cohort of 1410 individuals was followed for 33 years since 1980. Fasting and post-OGTT glucose parameters were used to categorize the cohort according to baseline glycemic status. The mortality rate increased from 43% in normoglycemic individuals to 53.3, 61.7, 72.9 and 88.0% in those with impaired fasting glucose (IFG), impaired glucose tolerance (IGT), IFG/IGT and diabetes, respectively. The highest mortality rate, compared with the normoglycemic category, was observed in individuals with IFG/IGT and diabetes according to a Cox proportional hazard model (HR = 1.38, 95%CI 1.10-1.74 and HR = 2.14, 95%CI 1.70-2.70, respectively), followed by individuals with IGT and IFG, but this did not reach statistical significance. We speculate that the IFG group may represent a mixture of individuals en route from normal to the next two categories as well as another cohort whose glucose levels are stably set at the upper reaches of the normal distribution. Significant differences were found between 1 and 2 h glucose values (p < 0.001). Fasting, 60 and 120 min glucose values were positively associated with increasing HbA1 quintiles (p < 0.05). The mean HbA1 was significantly higher in those who died (p = 0.01). The highest mortality (58.8%) was observed in the upper HbA1 quintile that was also associated with the highest prevalence of the metabolic syndrome (17.2%). This study shows a continuous relationship between the severity of dysglycemia and long-term mortality and should promote the early recognition of prediabetes. The 1 h post-load glucose level was continuously associated with increasing HbA1 concentrations and may therefore serve as an early marker for abnormalities in glucose tolerance. An elevated 1 h post-load glucose level may

Long-Term Dynamics of Autonomous Fractional Differential Equations

NASA Astrophysics Data System (ADS)

Liu, Tao; Xu, Wei; Xu, Yong; Han, Qun

This paper aims to investigate long-term dynamic behaviors of autonomous fractional differential equations with effective numerical method. The long-term dynamic behaviors predict where systems are heading after long-term evolution. We make some modification and transplant cell mapping methods to autonomous fractional differential equations. The mapping time duration of cell mapping is enlarged to deal with the long memory effect. Three illustrative examples, i.e. fractional Lotka-Volterra equation, fractional van der Pol oscillator and fractional Duffing equation, are studied with our revised generalized cell mapping method. We obtain long-term dynamics, such as attractors, basins of attraction, and saddles. Compared with some existing stability and numerical results, the validity of our method is verified. Furthermore, we find that the fractional order has its effect on the long-term dynamics of autonomous fractional differential equations.

Beyond Traditional Newspaper Advertisement: Leveraging Facebook-Targeted Advertisement to Recruit Long-Term Smokers for Research

PubMed Central

Warrick, Adam

2016-01-01

Background Smokers are a stigmatized population, but an important population to reach for the purpose of research. Therefore, innovative recruitment methods are needed that are both cost-effective and efficacious in recruiting this population. Objective The aim of the present article was to evaluate the feasibility of Facebook-targeted advertisement to recruit long-term smokers eligible for lung cancer screening for a descriptive, cross-sectional survey. Methods A social media recruitment campaign was launched using Facebook-targeted advertisement to target age and keywords related to tobacco smoking in the Facebook users profile, interests, and likes. A 3-day newspaper advertisement recruitment campaign was used as a comparison. The study that used both recruitment methods aimed to test the psychometric properties of 4 newly developed lung cancer screening health belief scales. Data were collected via cross-sectional survey methodology using an Web-based survey platform. Results The Facebook-targeted advertisements were viewed 56,621 times over an 18-day campaign in 2015 in the United States. The advertisement campaign yielded 1121 unique clicks to the Web-based survey platform at a cost of $1.51 per completed survey. Of those who clicked through to the study survey platform, 423 (37.7%) consented to participate; 92 (8.2%) dropped out during completion of the survey yielding a final study pool of 331 completed surveys. Recruitment by newspaper advertisement yielded a total of 30 participants in response to a 3-day advertisement campaign; recruitment efficacy resulted in 10 participants/day at $40.80 per completed survey. Participants represented current (n=182; 51%) and former smokers (n=178; 49%) with a mean age of 63.4 years (SD 6.0). Cost of the advertisement campaign was $500 total for the 18-day campaign. Conclusions Recruitment by Facebook was more efficacious and cost-effective compared with newspaper advertisement. Facebook offers a new venue for

Beyond Traditional Newspaper Advertisement: Leveraging Facebook-Targeted Advertisement to Recruit Long-Term Smokers for Research.

PubMed

Carter-Harris, Lisa; Bartlett Ellis, Rebecca; Warrick, Adam; Rawl, Susan

2016-06-15

Smokers are a stigmatized population, but an important population to reach for the purpose of research. Therefore, innovative recruitment methods are needed that are both cost-effective and efficacious in recruiting this population. The aim of the present article was to evaluate the feasibility of Facebook-targeted advertisement to recruit long-term smokers eligible for lung cancer screening for a descriptive, cross-sectional survey. A social media recruitment campaign was launched using Facebook-targeted advertisement to target age and keywords related to tobacco smoking in the Facebook users profile, interests, and likes. A 3-day newspaper advertisement recruitment campaign was used as a comparison. The study that used both recruitment methods aimed to test the psychometric properties of 4 newly developed lung cancer screening health belief scales. Data were collected via cross-sectional survey methodology using an Web-based survey platform. The Facebook-targeted advertisements were viewed 56,621 times over an 18-day campaign in 2015 in the United States. The advertisement campaign yielded 1121 unique clicks to the Web-based survey platform at a cost of $1.51 per completed survey. Of those who clicked through to the study survey platform, 423 (37.7%) consented to participate; 92 (8.2%) dropped out during completion of the survey yielding a final study pool of 331 completed surveys. Recruitment by newspaper advertisement yielded a total of 30 participants in response to a 3-day advertisement campaign; recruitment efficacy resulted in 10 participants/day at $40.80 per completed survey. Participants represented current (n=182; 51%) and former smokers (n=178; 49%) with a mean age of 63.4 years (SD 6.0). Cost of the advertisement campaign was $500 total for the 18-day campaign. Recruitment by Facebook was more efficacious and cost-effective compared with newspaper advertisement. Facebook offers a new venue for recruitment into research studies that offer the potential

Fondaparinux in the initial and long-term treatment of venous thromboembolism.

PubMed

Pesavento, Raffaele; Amitrano, Maria; Trujillo-Santos, Javier; Di Micco, Pierpaolo; Mangiacapra, Sara; López-Jiménez, Luciano; Falgá, Conxita; García-Bragado, Fernando; Piovella, Chiara; Prandoni, Paolo; Monreal, Manuel

2015-02-01

Even in the absence of evidence on its long-term efficacy and safety, a number of patients with venous thromboembolism (VTE) receive long-term therapy with fondaparinux alone in everyday practice. We used the Registro Informatizado de Enfermedad Tromboembólica (RIETE) registry to compare the rate of VTE recurrences and major bleeding at 10 and 90 days in patients with and without cancer. For long-term therapy, fondaparinux was compared with vitamin K antagonists (VKA) in patients without cancer and with low-molecular-weight heparin (LMWH) in those with cancer. Of 47,378 patients recruited, 46,513 were initially treated with heparin, 865 with fondaparinux. Then, 263 patients (78 with cancer) were treated for at least 3 months with fondaparinux. After propensity-score matching, there were no differences between patients receiving initial therapy with heparin or fondaparinux. Among patients with cancer, there were no differences between fondaparinux and LMWH. Among patients without cancer, the long-term use of fondaparinux was associated with an increased risk of major bleeding (3.24 % vs. 0.95 %, p<0.05). An unexpected high rate of major bleeding was observed in non-cancer patients treated with long-term fondaparinux. Our small sample does not allow to derive relevant conclusions on the use of fondaparinux in cancer patients. Copyright © 2014 Elsevier Ltd. All rights reserved.

The Womanly World of Long Term Care: The Plight of the Long Term Care Worker. Gray Paper.

ERIC Educational Resources Information Center

Older Women's League, Washington, DC.

Long-term care workers (those who are paid to provide custodial care for long-term patients in nursing homes or at home) must care for a growing number of increasingly disabled or dependent persons. They are working for agencies and institutions under growing pressure to increase productivity. They face new training and competency requirements,…

Long-term Response of Cerebrospinal Fluid Pressure in Patients with Idiopathic Intracranial Hypertension - A Prospective Observational Study.

PubMed

Gafoor, V Abdul; Smita, B; Jose, James

2017-01-01

Idiopathic intracranial hypertension (IIH) is increased intracranial pressure (ICP) with normal cerebrospinal fluid (CSF) contents, in the absence of an intracranial mass, hydrocephalus, or other identifiable causes. The current knowledge of the treatment outcome of IIH is limited, and the data on the natural history of this entity are scant. The objective of the study is to study the treatment response of IIH by serially measuring the CSF opening pressure and to delineate the factors influencing the same. A prospective observational study in a cohort of fifty patients with IIH in whom CSF opening pressure was serially measured at pre-specified intervals. The mean CSF opening pressure at baseline was 302.4 ± 51.69 mm of H 2 O (range: 220-410). Even though a higher body mass index (BMI) showed a trend toward a higher CSF opening pressure, the association was not significant ( P = 0.168). However, the age of the patient had a significant negative correlation with the CSF pressure ( P = 0.006). The maximum reduction in CSF pressure occurred in the first 3 months of treatment, and thereafter it plateaued. Remission was attained in 12 (24%) patients. BMI had the strongest association with remission ( P = 0.001). In patients with IIH, treatment response is strongly related to BMI. However, patients with normal BMI are also shown to relapse and hence should have continuous, long-term follow-up. The reduction in CSF pressure attained in the first 3 months could reflect the long-term response to treatment.

Long-term weather predictability: Ural case study

NASA Astrophysics Data System (ADS)

Kubyshen, Alexander; Shopin, Sergey

2016-04-01

The accuracy of the state-of-the-art long-term meteorological forecast (at the seasonal level) is still low. Here it is presented approach (RAMES method) realizing different forecasting methodology. It provides prediction horizon of up to 19-22 years under equal probabilities of determination of parameters in every analyzed period [1]. Basic statements of the method are the following. 1. Long-term forecast on the basis of numerical modeling of the global meteorological process is principally impossible. Extension of long-term prediction horizon could be obtained only by the revealing and using a periodicity of meteorological situations at one point of observation. 2. Conventional calendar is unsuitable for generalization of meteorological data and revealing of cyclicity of meteorological processes. RAMES method uses natural time intervals: one day, synodic month and one year. It was developed a set of special calendars using these natural periods and the Metonic cycle. 3. Long-term time series of meteorological data is not a uniform universal set, it is a sequence of 28 universal sets appropriately superseding each other in time. The specifics of the method are: 1. Usage of the original research toolkit consisting of - a set of calendars based on the Metonic cycle; - a set of charts (coordinate systems) for the construction of sequence diagrams (of daily variability of a meteorological parameter during the analyzed year; of daily variability of a meteorological parameter using long-term dynamical time series of periods-analogues; of monthly and yearly variability of accumulated value of meteorological parameter). 2. Identification and usage of new virtual meteorological objects having several degrees of generalization appropriately located in the used coordinate systems. 3. All calculations are integrated into the single technological scheme providing comparison and mutual verification of calculation results. During the prolonged testing in the Ural region, it was

Differences in the verbal fluency, working memory and executive functions in alcoholics: Short-term vs. long-term abstainers.

PubMed

Nowakowska-Domagała, Katarzyna; Jabłkowska-Górecka, Karolina; Mokros, Łukasz; Koprowicz, Jacek; Pietras, Tadeusz

2017-03-01

The aim of the study was to assess differences in verbal fluency, working memory and executive functions in two subgroups of alcohol-dependent patients, those undergoing short-term abstinence (STA) and those undergoing long-term abstinence (LTA), and to compare the level of cognitive functions in patients after long-term abstinence with healthy subjects. The study group consisted of 106 alcohol-dependent patients (53 immediately after drinking at least 3 days and 53 after at least one-year abstinence). The control group comprised 53 subjects, whose age, sex and education levels matched those of the patients in the experimental group. The dependence intensity was assessed using SADD and MAST scales. The neuropsychological assessment was based on the FAS Test, Stroop Test and TMT A&B Test. The results obtained for alcohol-dependent patients revealed significant disturbances of cognitive functions. Such results indicate the presence of severe frontal cerebral cortex dysfunctions. Frontal cortex dysfunctions affecting the verbal fluency and working memory subsystems and the executive functions also persisted during long-term abstinence periods. No significant correlations between the duration of dependence, quantity of alcohol consumed and efficiency of the working memory and executive functions were observed in alcohol-dependent subjects after short-term or long-term abstinence. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

Coordinated Multiwavelength Observations of PKS 0528+134 in Quiescence

NASA Astrophysics Data System (ADS)

Boettcher, Markus; Palma, N.

2011-01-01

We report results of an intensive multiwavelength campaign on the prominent high-redshift (z = 2.06) gamma-ray bright blazar PKS 0528+134 in September - October 2009. The campaign was centered on four 30 ksec pointings with XMM-Newton, supplemented with ground-based optical (MDM, Perkins) and radio (UMRAO, Medicina, Metsaehovi, Noto, SMA) observations as well as long-term X-ray monitoring with RXTE and gamma-ray monitoring by Fermi. We find significant variability on 1 day time scales in the optical regime, accompanied by a weak redder-when-brighter trend. X-ray variability is found on longer ( 1 week) time scales, while the Fermi light curve shows no evidence for variability, neither in flux nor spectral index. We constructed four simultaneous spectral energy distributions, which can all be fit satisfactorily with a one-zone leptonic jet model. This work was supported by NASA through XMM-Newton Guest Observer Grant NNX09AV45G.

Biomass Burning Observation Project (BBOP) Final Campaign Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kleinman, LI; Sedlacek, A. J.

2016-01-01

The Biomass Burning Observation Project (BBOP) was conducted to obtain a better understanding of how aerosols generated from biomass fires affect the atmosphere and climate. It is estimated that 40% of carbonaceous aerosol produced originates from biomass burning—enough to affect regional and global climate. Several biomass-burning studies have focused on tropical climates; however, few campaigns have been conducted within the United States, where millions of acres are burned each year, trending to higher values and greater climate impacts because of droughts in the West. Using the Atmospheric Radiation Measurement (ARM) Aerial Facility (AAF), the BBOP deployed the Gulfstream-1 (G-1) aircraftmore » over smoke plumes from active wildfire and agricultural burns to help identify the impact of these events and how impacts evolve with time. BBOP was one of very few studies that targeted the near-field time evolution of aerosols and aimed to obtain a process-level understanding of the large changes that occur within a few hours of atmospheric processing.« less

Observations of an Intermediate Layer During the Coqui II Campaign

NASA Technical Reports Server (NTRS)

Bishop, R. L.; Earle, G. D.; Herrero, F. A.; Bateman, T. T.

2000-01-01

NASA sounding rocket 21.114, launched March 7, 1998, during the Coqui II campaign, provided neutral wind and plasma density measurements of a weak intermediate layer. The layer was centered near 140 km and had an approximate peak plasma density of 2200 cc. The measured winds were typically less than 40 m/s, in agreement with wind shear formation theory and coincident density observations. The data obtained during the flight allow us to explore the plasma density structure and wind field morphology of the intermediate layer. Coupled with simultaneous data from Arecibo Observatory, the upleg and downleg density profiles provide three spatially separated measurements that enable the first detailed investigation of the horizontal extent and variation of an intermediate layer.

Long-term studies of dopamine agonists.

PubMed

Hubble, Jean P

2002-02-26

Dopamine agonists have long been used as adjunctive therapy for the treatment of Parkinson's disease (PD). In more recent years these drugs have also been proved safe and effective as initial therapy in lieu of levodopa in the treatment of PD. Long-term levodopa therapy is associated with motor complications, including fluctuating response patterns and dyskinesia. By initially introducing a dopamine agonist as symptomatic drug therapy, it may be possible to postpone the use of levodopa and delay or prevent the development of motor complications. Recently, four clinical trials have explored this hypothesis by comparing the long-term response and side effects of levodopa with dopamine agonist therapy. The drugs studied have included ropinirole, pramipexole, cabergoline, and pergolide. In each of these projects, the occurrence of motor complications, such as wearing off and dyskinesia, was significantly less in the subjects assigned to initiation of therapy with a dopamine agonist. The addition of levodopa could be postponed by many months or even several years. Therefore, these long-term studies of dopamine agonists support the initiation of a dopamine agonist instead of levodopa in an effort to postpone levodopa-related motor complications. This therapeutic approach may be particularly appropriate in PD patients with a long treatment horizon on the basis of age and general good health. The extension phase of the long-term study comparing pramipexole with levodopa is ongoing, and follow-up information may help to establish the value of this treatment strategy.

Nitrogen Dioxide long term trends at mid and high latitudes by means of ground based observations

NASA Astrophysics Data System (ADS)

Bortoli, D.; Petritoli, A.; Giovanelli, G.; Kostadinov, I.; Ravegnani, F.

2003-04-01

The interactions between mid- and high latitudes atmospheric changes are going to be one of the main issue for the future of stratospheric and tropospheric chemistry research. A more detailed study of the ozone trends as well as a wider comprehension of the interactions with lower and higher latitudes are maybe the main arguments to which scientist should address their works in order to build-up a more detailed picture of what scenarios we have to face in the near future. GASCODs type spectrometers (Gas Analyzer Spectrometer Correlating Optical Differences) are installed at the "Ottavio Vittori" research station (44.11N, 10.42E, 2165 m asl) since June 1993, at the Italian Antarctic Station (74.69S, 164.12E) since December 1995 and at the STIL-BAS station (42.42N, 25.63E) since 1999. The instruments measure zenith scattered solar radiation between 407 and 464 nm. Nitrogen dioxide total column is retrieved with DOAS methodology. The seasonal trend of NO2 vc values is reported and it shows the expected behaviour: maximum values during the summer period while the minimum occur in the winter season in both the hemispheres. A typical behaviour of the AMPM ratio at high latitudes is highlight. A Fourier analysis is proposed as a tool to investigate the long-term components of nitrogen dioxide stratospheric amount. Results are presented and the NO2 trend is evidenced and commented. ACKNOWLEDGMENTS: The author Daniele Bortoli was financially supported by the Subprograma Ciência e Tecnologia do 3° Quadro Comunitário de Apoio. The National Antarctic Research Program (PNRA) and the Quantification and Interpretation of Long-Term UV-Vis Observations of the Stratosphere (QUILT) project supported this research.

Morphometric analysis of long-term dentoskeletal effects induced by treatment with Balters bionator.

PubMed

Bigliazzi, Renato; Franchi, Lorenzo; Bertoz, André Pinheiro de Magalhães; McNamara, James A; Faltin, Kurt; Bertoz, Francisco Antonio

2015-09-01

To evaluate the long-term effects of the standard (Class II) Balters bionator in growing patients with Class II malocclusion with mandibular retrusion by using morphometrics (thin-plate spline [TPS] analysis). Twenty-three Class II patients (8 male, 15 female) were treated consecutively with the Balters bionator (bionator group). The sample was evaluated at T0, start of treatment; T1, end of bionator therapy; and T2, long-term observation (including fixed appliances). Mean age at the start of treatment was 10 years 2 months (T0); at posttreatment, 12 years 3 months (T1); and at long-term follow-up, 18 years 2 months (T2). The control group consisted of 22 subjects (11 male, 11 female) with untreated Class II malocclusion. Lateral cephalograms were analyzed at the three time points for all groups. TPS analysis evaluated statistical differences (permutation tests) in the craniofacial shape and size between the bionator and control groups. TPS analysis showed that treatment with the bionator is able to produce favorable mandibular shape changes (forward and downward displacement) that contribute significantly to the correction of the Class II dentoskeletal imbalance. These results are maintained at a long-term observation after completion of growth. The control group showed no statistically significant differences in the correction of Class II malocclusion. This study suggests that bionator treatment of Class II malocclusion produces favorable results over the long term with a combination of skeletal and dentoalveolar shape changes.

The essential value of long-term experimental data for hydrology and water management

NASA Astrophysics Data System (ADS)

Tetzlaff, Doerthe; Carey, Sean K.; McNamara, James P.; Laudon, Hjalmar; Soulsby, Chris

2017-04-01

Observations and data from long-term experimental watersheds are the foundation of hydrology as a geoscience. They allow us to benchmark process understanding, observe trends and natural cycles, and are prerequisites for testing predictive models. Long-term experimental watersheds also are places where new measurement technologies are developed. These studies offer a crucial evidence base for understanding and managing the provision of clean water supplies, predicting and mitigating the effects of floods, and protecting ecosystem services provided by rivers and wetlands. They also show how to manage land and water in an integrated, sustainable way that reduces environmental and economic costs.

Exploiting Orbital Data and Observation Campaigns to Improve Space Debris Models

NASA Astrophysics Data System (ADS)

Braun, V.; Horstmann, A.; Reihs, B.; Lemmens, S.; Merz, K.; Krag, H.

The European Space Agency (ESA) has been developing the Meteoroid and Space Debris Terrestrial Environment Reference (MASTER) software as the European reference model for space debris for more than 25 years. It is an event-based simulation of all known individual debris-generating events since 1957, including breakups, solid rocket motor firings and nuclear reactor core ejections. In 2014, the upgraded Debris Risk Assessment and Mitigation Analysis (DRAMA) tool suite was released. In the same year an ESA instruction made the standard ISO 24113:2011 on space debris mitigation requirements, adopted via the European Cooperation for Space Standardization (ECSS), applicable to all ESA missions. In order to verify the compliance of a space mission with those requirements, the DRAMA software is used to assess collision avoidance statistics, estimate the remaining orbital lifetime and evaluate the on-ground risk for controlled and uncontrolled reentries. In this paper, the approach to validate the MASTER and DRAMA tools is outlined. For objects larger than 1 cm, thus potentially being observable from ground, the MASTER model has been validated through dedicated observation campaigns. Recent campaign results shall be discussed. Moreover, catalogue data from the Space Surveillance Network (SSN) has been used to correlate the larger objects. In DRAMA, the assessment of collision avoidance statistics is based on orbit uncertainty information derived from Conjunction Data Messages (CDM) provided by the Joint Space Operations Center (JSpOC). They were collected for more than 20 ESA spacecraft in the recent years. The way this information is going to be used in a future DRAMA version is outlined and the comparison of estimated manoeuvre rates with real manoeuvres from the operations of ESA spacecraft is shown.

Soil respiration is not limited by reductions in microbial biomass during long-term soil incubations

USDA-ARS?s Scientific Manuscript database

Declining rates of soil respiration are reliably observed during long-term laboratory incubations, but the cause is uncertain. We explored different controls on soil respiration during long-term soil incubations. Following a 707 day incubation (30 C) of soils from cultivated and forested plots at Ke...

Conceptual Distinctiveness Supports Detailed Visual Long-Term Memory for Real-World Objects

PubMed Central

Konkle, Talia; Brady, Timothy F.; Alvarez, George A.; Oliva, Aude

2012-01-01

Humans have a massive capacity to store detailed information in visual long-term memory. The present studies explored the fidelity of these visual long-term memory representations and examined how conceptual and perceptual features of object categories support this capacity. Observers viewed 2,800 object images with a different number of exemplars presented from each category. At test, observers indicated which of 2 exemplars they had previously studied. Memory performance was high and remained quite high (82% accuracy) with 16 exemplars from a category in memory, demonstrating a large memory capacity for object exemplars. However, memory performance decreased as more exemplars were held in memory, implying systematic categorical interference. Object categories with conceptually distinctive exemplars showed less interference in memory as the number of exemplars increased. Interference in memory was not predicted by the perceptual distinctiveness of exemplars from an object category, though these perceptual measures predicted visual search rates for an object target among exemplars. These data provide evidence that observers’ capacity to remember visual information in long-term memory depends more on conceptual structure than perceptual distinctiveness. PMID:20677899

Evaluation of a national universal coverage campaign of long-lasting insecticidal nets in a rural district in north-west Tanzania.

PubMed

West, Philippa A; Protopopoff, Natacha; Rowland, Mark W; Kirby, Matthew J; Oxborough, Richard M; Mosha, Franklin W; Malima, Robert; Kleinschmidt, Immo

2012-08-10

Insecticide-treated nets (ITN) are one of the most effective measures for preventing malaria. Mass distribution campaigns are being used to rapidly increase net coverage in at-risk populations. This study had two purposes: to evaluate the impact of a universal coverage campaign (UCC) of long-lasting insecticidal nets (LLINs) on LLIN ownership and usage, and to identify factors that may be associated with inadequate coverage. In 2011 two cross-sectional household surveys were conducted in 50 clusters in Muleba district, north-west Tanzania. Prior to the UCC 3,246 households were surveyed and 2,499 afterwards. Data on bed net ownership and usage, demographics of household members and household characteristics including factors related to socio-economic status were gathered, using an adapted version of the standard Malaria Indicator Survey. Specific questions relating to the UCC process were asked. The proportion of households with at least one ITN increased from 62.6% (95% Confidence Interval (CI) = 60.9-64.2) before the UCC to 90.8% (95% CI = 89.0-92.3) afterwards. ITN usage in all residents rose from 40.8% to 55.7%. After the UCC 58.4% (95% CI = 54.7-62.1) of households had sufficient ITNs to cover all their sleeping places. Households with children under five years (OR = 2.4, 95% CI = 1.9-2.9) and small households (OR = 1.9, 95% CI = 1.5-2.4) were most likely to reach universal coverage. Poverty was not associated with net coverage. Eighty percent of households surveyed received LLINs from the campaign. The UCC in Muleba district of Tanzania was equitable, greatly improving LLIN ownership and, more moderately, usage. However, the goal of universal coverage in terms of the adequate provision of nets was not achieved. Multiple, continuous delivery systems and education activities are required to maintain and improve bed net ownership and usage.

Long-term Efficacy of Vedolizumab for Crohn's Disease.

PubMed

Vermeire, Severine; Loftus, Edward V; Colombel, Jean-Frédéric; Feagan, Brian G; Sandborn, William J; Sands, Bruce E; Danese, Silvio; D'Haens, Geert R; Kaser, Arthur; Panaccione, Remo; Rubin, David T; Shafran, Ira; McAuliffe, Megan; Kaviya, Arpeat; Sankoh, Serap; Mody, Reema; Abhyankar, Brihad; Smyth, Michael

2017-04-01

Vedolizumab is a gut-selective α4β7 integrin antagonist therapy for ulcerative colitis and Crohn's disease. The GEMINI long-term safety [LTS] trial is an ongoing open-label study investigating the safety of vedolizumab. We present interim exploratory analyses of efficacy in patients with Crohn's disease. Patients from the C13004, GEMINI 2 and GEMINI 3 studies and vedolizumab-naïve patients could enrol in GEMINI LTS and received vedolizumab every 4 weeks. Data were collected from May 22, 2009 to June 27, 2013. Outcomes of clinical response and remission, defined by the Harvey-Bradshaw Index, and health-related quality of life [HRQL] were assessed for up to 152 weeks of treatment in the efficacy population. Among patients with response at week 6 in GEMINI 2 who received vedolizumab continuously, 83% [n=100/120] and 89% [n=62/70] of patients with available data were in remission after 104 and 152 weeks, respectively. Increased dosing frequency from every 8 weeks [GEMINI 2] to every 4 weeks [GEMINI LTS] improved outcomes in patients who had withdrawn early from GEMINI 2, with 47% [n=27/57] experiencing clinical response and 32% [n=18/57] in remission at week 52 of GEMINI LTS [up from 39% and 4% before the dose increase]. Similar improvements were observed regardless of prior tumour necrosis factor [TNF] antagonist exposure. Long-term benefits of HRQL were also observed. The clinical benefits of vedolizumab continued with long-term treatment regardless of prior TNF antagonist exposure. Increased dosing frequency might improve outcomes in patients who lose response to conventional 8-weekly dosing. Copyright © 2016 European Crohn’s and Colitis Organisation (ECCO). Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com

Long-term tinnitus suppression with linear octave frequency transposition hearing AIDS.

PubMed

Peltier, Elisabeth; Peltier, Cedric; Tahar, Stephanie; Alliot-Lugaz, Evelyne; Cazals, Yves

2012-01-01

Over the last three years of hearing aid dispensing, it was observed that among 74 subjects fitted with a linear octave frequency transposition (LOFT) hearing aid, 60 reported partial or complete tinnitus suppression during day and night, an effect still lasting after several months or years of daily use. We report in more details on 38 subjects from whom we obtained quantified measures of tinnitus suppression through visual analog scaling and several additional psychoacoustic and audiometric measures. The long-term suppression seems independent of subject age, and of duration and subjective localization of tinnitus. A small but significant correlation was found with audiogram losses but not with high frequency loss slope. Long-term tinnitus suppression was observed for different etiologies, but with a low success rate for sudden deafness. It should be noted that a majority of subjects (23) had a history of noise exposure. Tinnitus suppression started after a few days of LOFT hearing aid use and reached a maximum after a few weeks of daily use. For nine subjects different amounts of frequency shifting were tried and found more or less successful for long-term tinnitus suppression, no correlation was found with tinnitus pitch. When the use of the LOFT hearing aid was stopped tinnitus reappeared within a day, and after re-using the LOFT aid it disappeared again within a day. For about one third of the 38 subjects a classical amplification or a non linear frequency compression aid was also tried, and no such tinnitus suppression was observed. Besides improvements in audiometric sensitivity to high frequencies and in speech discrimination scores, LOFT can be considered as a remarkable opportunity to suppress tinnitus over a long time scale. From a pathophysiological viewpoint these observations seem to fit with a possible re-attribution of activity to previously deprived cerebral areas corresponding to high frequency coding.

Changing consumer attitudes to energy efficiency: Midterm results from an advertising campaign

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peters, J.S.; Seiden, K.; Baggett, S.

As utilities move away from rebates and incentives, many choose to use educational campaigns as a means to continue energy efficiency acquisition efforts. Measuring these effects is difficult and has long been considered nearly impossible by many in the evaluation community. Given the difficulty of observing behavior changes associated with education campaigns, this project sought to measure the likelihood that consumers exposed to a campaign will take the action. A model of behavior change, the theory of planned behavior developed by Icek Ajzen demonstrates that such is possible. This paper reports on the results of a longitudinal panel study ofmore » an energy efficiency mass-market educational campaign, using the Ajzen model with results from a five-wave survey of 1,200 targeted consumers and a control group of 1,200. The first wave collected pre-campaign data in Spring 1997. The authors compare these baseline data with data collected from the second and third survey waves, which were performed in Fall 1997 and Spring 1998, respectively.« less

Observational and Modeling-based Study of Corsica Thunderstorms: Preparation of the EXAEDRE Airborne Campaign

NASA Astrophysics Data System (ADS)

Defer, E.; Coquillat, S.; Lambert, D.; Pinty, J. P.; Prieur, S.; Caumont, O.; Labatut, L.; Nuret, M.; Blanchet, P.; Buguet, M.; Lalande, P.; Labrouche, G.; Pedeboy, S.; Lojou, J. Y.; Schwarzenboeck, A.; Delanoë, J.; Bourdon, A.; Guiraud, L.

2017-12-01

The 4-year EXAEDRE (EXploiting new Atmospheric Electricity Data for Research and the Environment; Oct 2016-Sept 2020) project is sponsored by the French Science Foundation ANR (Agence Nationale de la Recherche). This project is a French contribution to the HyMeX (HYdrological cycle in the Mediterranean EXperiment) program. The EXAEDRE activities rely on innovative multi-disciplinary and state of the art instrumentation and modeling tools to provide a comprehensive description of the electrical activity in thunderstorms. The EXAEDRE observational part is based on i) existing lightning records collected during HyMeX Special Observation Period (SOP1; Sept-Nov 2012), and permanent lightning observations provided by the research Lightning Mapping Array SAETTA and the operational Météorage lightning locating systems, ii) additional lightning observations mapped with a new VHF interferometer especially developed within the EXAEDRE project, and iii) a dedicated airborne campaign over Corsica. The modeling part of the EXAEDRE project exploits the electrification and lightning schemes developed in the cloud resolving model MesoNH and promotes an innovative technique of flash data assimilation in the french operational model AROME of Météo-France. An overview of the EXAEDRE project will be given with an emphasis on the instrumental, observational and modeling activities performed during the 1st year of the project. The preparation of the EXAEDRE airborne campaign scheduled for September 2018 over Corsica will then be discussed. Acknowledgements. The EXAEDRE project is sponsored by grant ANR-16-CE04-0005 with support from the MISTRALS/HyMeX meta program.

Long-term course of orthostatic tremor in serial posturographic measurement.

PubMed

Feil, K; Böttcher, N; Guri, F; Krafczyk, S; Schöberl, F; Zwergal, A; Strupp, M

2015-08-01

Primary orthostatic tremor (OT) is a rare neurological disease of unknown pathophysiology characterized by a high-frequency tremor mainly of the legs when standing. The aim of this study was to examine its long-term course by subjective estimation and objective recording by serial posturography and to obtain further standardized epidemiological and clinical data on patients with OT. A clinical cohort of 37 patients with the diagnosis of primary OT was screened for this longitudinal follow-up study. Eighteen patients consented to participate. During study visit all patients underwent a standardized neurological examination and completed subjective scales and scores. Posturographic recordings at follow-up were compared to prior clinical posturographic measurements in 15 cases. In our cohort the mean duration of symptoms was 14.1 ± 6.8 years. Subjectively, 78% of patients reported progression of the disease. Posturographic data (5.4 ± 4.0 years) revealed a significant increase of the total sway path (standing on firm ground with eyes open) from 2.4 ± 1.3 to 3.4 ± 1.4 m/min (p = 0.022) and of the total root mean square values from 9.8 ± 4.3 to 12.4 ± 4.8 mm (p = 0.028). None of these observations are explained by aging of the patients. Mean frequency of the tremor did not change over time (14.7 ± 1.9 Hz vs. 14.9 ± 2.0 Hz at follow-up). Clinically, most patients had signs of cerebellar dysfunction and a substantial portion also showed proprioceptive deficits in the long-term course. This long-term follow-up study indicates, that primary OT is a progressive disorder. Furthermore, the clinical observation of cerebellar dysfunction in most OT patients in the long-term course might indicate an important role of the cerebellum in its pathophysiology. Copyright © 2015 Elsevier Ltd. All rights reserved.

Sounding rocket/ground-based observation campaign to study Medium-Scale Traveling Ionospheric Disturbances (MSTID)

NASA Astrophysics Data System (ADS)

Yamamoto, Mamoru; Otsuka, Yuichi; Abe, Takumi; Yokoyama, Tatsuhiro; Bernhardt, Paul; Watanabe, Shigeto; Yamamoto, Masa-yuki; Larsen, Miguel; Saito, Akinori; Pfaff, Robert; Ishisaka, Keigo

2012-07-01

An observation campaign is under preparation. It is to launch sounding rockets S-520-27 and S-310-42 from Uchinoura Space Center of JAXA, while ground-based instruments measure waves in the ionosphere. The main purpose of the study is to reveal seeding mechanism of Medium-Scale Traveling Ionospheric Disturbances (MSTID). The MSTID is enhanced in the summer nighttime of the mid-latitude ionosphere. The MSTID is not only a simple reflection of atmospheric waves to the ionosphere, but includes complicated processes including the electromagnetic coupling of the F- and E-regions, and inter-hemisphere coupling of the ionosphere. We will measure ionospheric parameters such as electron density and electric fields together with neutral winds in the E- and F-regions. TMA and Lithium release experiment will be conducted with S-310-42 and S-520-27 rockets, respectively. The observation campaign is planned in summer 2012 or 2013. In the presentation we will overview characteristics of MSTID, and show plan and current status of the project. We also touch results from the sounding rocket S-520-26 that was launched on January 12, 2012. We will show results of the rocket-ground dual-band beacon experiment.

Long-Term Dynamic Monitoring of the Historical Masonry FAÇADE: the Case of Palazzo Ducale in Venice, Italy

NASA Astrophysics Data System (ADS)

Noh, J.; Russo, S.

2017-08-01

Long-term dynamic monitoring of the masonry façade of Palazzo Ducale known as Doge's palace in Venice, Italy was performed from September 2010 to October 2012. This article demonstrates the results of preliminary analysis on the data set of the first 12-month long monitoring campaign for out-of-plumb dynamic responses of the medieval façade of the monument. The aim of the analysis of the dynamic signals is to validate the data set and investigate dynamic characteristics of the vibration signature of the historical masonry wall in the long-term. Palazzo Ducale is a heavily visited heritage due to its high cultural importance and architectural value. Nevertheless, little is known about the dynamic behaviour of the double-leaf masonry façade. In this study, the dynamic properties of the structure are presented by dynamic identification carried out with the effect of the ambient vibration measured at four different locations on the façade and portico level. The trend and intensity of the vibration at each measurement locations are identified over the year. In addition, the issue on eliminating the noise blended in the signals for reliable analysis are also discussed.

Long Term TOA - M Data and Information

Atmospheric Science Data Center

2017-09-06

... A Long-Term TOA and Constrained Surface Radiation Budget Project A Long-Term TOA and Constrained Surface Readiation ... Budget Experiment (ERBE) and Clouds and the Earth's Radiant Energy System (CERES), that span nearly 30 years to date.   The ...

Cessation Outcomes Among Quitline Callers in Three States During a National Tobacco Education Campaign.

PubMed

Vickerman, Katrina A; Zhang, Lei; Malarcher, Ann; Mowery, Paul; Nash, Chelsea

2015-07-16

Antismoking mass media campaigns, such as the Centers for Disease Control and Prevention's Tips from Former Smokers (Tips) campaign, increase the number of tobacco users calling tobacco quitlines. Few studies have investigated long-term tobacco use cessation for callers during antismoking media campaigns. Studies have suggested that callers during campaigns may be less committed to quitting and have lower quit rates. This study examines tobacco user cessation outcomes 7 months after quitline enrollment during the 2012 Tips campaign (March 19 through June 10, 2012). We analyzed data for 715 tobacco users who enrolled in the Nebraska, North Carolina, or Texas state quitline multiple-call programs during the 2012 Tips campaign and responded to a 7-month postenrollment survey (38.5% survey response rate). We used multivariable logistic regression analyses to determine whether 7-day and 30-day point prevalence abstinence rates 7 months after enrollment were related to level of exposure to the campaign. In multivariable models, only lower nicotine dependence and higher call completion were associated with higher odds of 7-day and 30-day abstinence 7 months after enrollment. Tips campaign exposure was not associated with abstinence. Once enrolled in quitline counseling, quitline callers achieved similar outcomes regardless of Tips campaign exposure levels. While the campaign did not appear to directly affect odds of tobacco abstinence through quitlines, antismoking mass media campaigns such as Tips are valuable in increasing tobacco users' exposure to quitlines and thus increasing their likelihood of making a quit attempt and eventually achieving tobacco abstinence.

Long-term biological investigations in space.

PubMed

Lotz, R G; Fuchs, H; Bertsche, U

1975-01-01

Missions in space within the next two decades will be of longer duration than those carried out up to the present time, and the effects of such long-term flights on biological organisms are unknown. Results of biological experiments that have been performed to date cannot be extrapolated to results in future flights because of the unknown influence of adaptation over a long period of time. Prior experiments with Axolotl, fishes, and vertebrates by our research team (in part with sounding rockets) showed that these specimens did not appear to be suitable for long-term missions on which minimization of expense, technique, and energy is required. Subsequent investigations have shown the suitability of the leech (Hirudo medicinalis), which consumes blood of mammals up to ten times its own weight (1 g) and can live more than 2 years without further food supply. Emphasis in the experiments with Hirudo medicinalis is placed on metabolic rhythm and motility. Resorption and diffusion in tissue, development, and growth under long-term effects of cosmic proton radiation and zero-gravity are other focal points. The constancy of cellular life in the mature animals is a point in favor of these specimens. We have also taken into account the synergistic effects of the space environment on the problems just mentioned. The life-support system constructed for the leech has been tested successfully in four sounding rocket flights and, on that basis, has been prepared for a long-term mission. Long-term investigations out of the terrestrial biosphere will provide us with information concerning the degree of adaptation of certain physiological and biochemical functions and as to what extent biological readjustment or repair processes can occur under the specific stress conditions of space flight.

Arctic springtime observations of volatile organic compounds during the OASIS-2009 campaign

NASA Astrophysics Data System (ADS)

Hornbrook, Rebecca S.; Hills, Alan J.; Riemer, Daniel D.; Abdelhamid, Aroob; Flocke, Frank M.; Hall, Samuel R.; Huey, L. Gregory; Knapp, David J.; Liao, Jin; Mauldin, Roy L.; Montzka, Denise D.; Orlando, John J.; Shepson, Paul B.; Sive, Barkley; Staebler, Ralf M.; Tanner, David. J.; Thompson, Chelsea R.; Turnipseed, Andrew; Ullmann, Kirk; Weinheimer, Andrew J.; Apel, Eric C.

2016-08-01

Gas-phase volatile organic compounds (VOCs) were measured at three vertical levels between 0.6 m and 5.4 m in the Arctic boundary layer in Barrow, Alaska, for the Ocean-Atmosphere-Sea Ice-Snowpack (OASIS)-2009 field campaign during March-April 2009. C4-C8 nonmethane hydrocarbons (NMHCs) and oxygenated VOCs (OVOCs), including alcohols, aldehydes, and ketones, were quantified multiple times per hour, day and night, during the campaign using in situ fast gas chromatography-mass spectrometry. Three canister samples were also collected daily and subsequently analyzed for C2-C5 NMHCs. The NMHCs and aldehydes demonstrated an overall decrease in mixing ratios during the experiment, whereas acetone and 2-butanone showed increases. Calculations of time-integrated concentrations of Br atoms, ∫[Br]dt, yielded values as high as (1.34 ± 0.27) × 1014 cm-3 s during the longest observed ozone depletion event (ODE) of the campaign and were correlated with the steady state Br calculated at the site during this time. Both chlorine and bromine chemistry contributed to the large perturbations on the production and losses of VOCs. Notably, acetaldehyde, propanal, and butanal mixing ratios dropped below the detection limit of the instrument (3 parts per trillion by volume (pptv) for acetaldehyde and propanal, 2 pptv for butanal) during several ODEs due to Br chemistry. Chemical flux calculations of OVOC production and loss are consistent with localized high Cl-atom concentrations either regionally or within a very shallow surface layer, while the deeper Arctic boundary layer provides a continuous source of precursor alkanes to maintain the OVOC mixing ratios.

Lidar observation campaign of sugar cane fires and industrial emissions in the State of São Paulo, Brazil

NASA Astrophysics Data System (ADS)

Landulfo, E.; Jorge, Maria Paulete M. P.; Held, Gerhard; Guardani, Roberto; Steffens, Juliana; dos Anjos F. Pinto, Sergio; Andre, Iara R.; Garcia, Gilberto; Lopes, F. J. S.; Mariano, Glauber L.; da Costa, Renata F.; Rodrigues, Patricia F.

2010-10-01

Brazil has an important role in the biomass burning, with the detection of approximately 100,000 burning spots in a single year (2007). Most of these spots occur in the southern part of the Amazon basin during the dry season (from August to november) and these emissions reach the southeast of the country, a highly populated region and with serious urban air pollution problems. With the growing demand on biofuels, sugarcane is considerably expanding in the state of Sao Paulo, being a strong contributor to the bad air quality in this region. In the state of Sao Paulo, the main land use are pasture and sugarcane crop, that covers around 50% and 10% of the total area, respectively. Despite the aerosol from sugarcane burning having reduced atmospheric residence time, from a few days to some weeks, they might get together with those aerosol which spread over long distances (hundreds to thousands of kilometers). In the period of June through February 2010 a LIDAR observation campaign was carried in the state of Sao Paulo, Brazil, in order to observe and characterize optically the aerosols from two distinct sources, namely, sugar cane biomass burning and industrial emissions. For this purpose 2 LIDAR systems were available, one mobile and the other placed in a laboratory, both working in the visible (532 nm) and additionally the mobile system had a Raman channel available (607 nm). Also this campaign counted with a SODAR, a meteorological RADAR specially set up to detect aerosol "echoes" and gas-particle analyzers. To guarantee a good regional coverage 4 distinct sites were available to deploy the instruments, 2 in the near field of biomass burning activities (Rio Claro and Bauru), one for industrial emissions (Cubatao) and others from urban sources (Sao Paulo). The whole campaign provide the equivalent of 30 days of measurements which allowed us to get aerosol optical properties such as backscattering/extinction coefficients, scatter and LIDAR ratios, those were used to

Embolization of renal angiomyolipomas: short-term and long-term outcomes, complications, and tumor shrinkage.

PubMed

Lee, Shen-Yang; Hsu, Hsiang-Hao; Chen, Yung-Chang; Huang, Chen-Chih; Wong, Yon-Cheong; Wang, Li-Jen; Chuang, Cheng-Keng; Yang, Chih-Wei

2009-11-01

This study retrospectively evaluated outcomes, complications, and tumor shrinkage in renal angiomyolipomas after transcatheter arterial embolization (TAE). All renal angiomyolipoma patients who underwent TAE between August 2000 and December 2008 and had short-term (long-term (>6 months) follow-up images were evaluated. Complications and tumor relapse after TAE were reviewed. The sizes of embolized tumors were measured to calculate size reductions and reduction rates after TAE. Differences in tumor size, size reduction, and reduction rate between different time points (pre-TAE, short-term follow-up, and long-term follow-up) and groups (completely and incompletely embolized) were determined. Eleven renal angiomyolipoma patients who had undergone TAE were included. Seven (63.6%) patients had postembolization syndrome and one had abscess formation following TAE. Two patients had a tumor relapse (18.2%). The mean tumor size was 8.57+/-2.66 cm on pre-TAE images. The mean size reduction was 3.1 cm (33.3%) and 3.8 cm (43.0%) at short-term and long-term follow-up. Tumor sizes differed significantly between pre-TAE and short-term (p=0.004) or long-term images (p=0.022) but not between short-term and long-term images (p=0.059). Results stratified by the completeness of embolization indicate that only the short-term size reduction rate differed significantly (p=0.025), while the long-term reduction rate and short- and long-term follow-up tumor size and size reduction were comparable between the two groups. In conclusion, selective TAE is effective for tumor shrinkage in most renal angiomyolipomas, with acceptable complication and relapse rates. Tumor shrinkage occurring within 6 months after TAE may reflect the long-term effect of TAE.

Global estimation of long-term persistence in annual river runoff

NASA Astrophysics Data System (ADS)

Markonis, Y.; Moustakis, Y.; Nasika, C.; Sychova, P.; Dimitriadis, P.; Hanel, M.; Máca, P.; Papalexiou, S. M.

2018-03-01

Long-term persistence (LTP) of annual river runoff is a topic of ongoing hydrological research, due to its implications to water resources management. Here, we estimate its strength, measured by the Hurst coefficient H, in 696 annual, globally distributed, streamflow records with at least 80 years of data. We use three estimation methods (maximum likelihood estimator, Whittle estimator and least squares variance) resulting in similar mean values of H close to 0.65. Subsequently, we explore potential factors influencing H by two linear (Spearman's rank correlation, multiple linear regression) and two non-linear (self-organizing maps, random forests) techniques. Catchment area is found to be crucial for medium to larger watersheds, while climatic controls, such as aridity index, have higher impact to smaller ones. Our findings indicate that long-term persistence is weaker than found in other studies, suggesting that enhanced LTP is encountered in large-catchment rivers, were the effect of spatial aggregation is more intense. However, we also show that the estimated values of H can be reproduced by a short-term persistence stochastic model such as an auto-regressive AR(1) process. A direct consequence is that some of the most common methods for the estimation of H coefficient, might not be suitable for discriminating short- and long-term persistence even in long observational records.

Results of the 2017 Mexican Asteroid Photometry Campaign - Part 1

NASA Astrophysics Data System (ADS)

Sada, Pedro; Loera-Gonzalez, Pablo; Olguin, Lorenzo; Saucedo-Morales, Julio C.; Ayala-Gómez, Sandra A.; Garza, Jaime R.

2018-04-01

We report the results for the first semester of the 2017 Mexican Asteroid Photometry Campaign. Asteroid 1218 Aster (synodic period of 3.1581 ± 0.0002 h and amplitude of 0.35 mag) was well observed and showed slight variations of its lightcurve at the end of the seven week observing window. An uncertain, but long, period of 93.23 ± 0.02 h and amplitude of 0.36 mag were estimated for 2733 Hamina from sparse data. Asteroid 8443 Svecica was also well observed and yielded a period of 20.9905 ± 0.0015 h and amplitude of 0.65 mag. Observations of NEA (143404) 2003 BD44 also resulted in an uncertain and long period of 78.617 ± 0.009 h and amplitude of 0.66 mag with a sparsely covered lightcurve.

Long-term modulation of cosmic rays during solar cycle 21

NASA Technical Reports Server (NTRS)

Fenton, A. G.; Fenton, K. B.; Humble, J. E.

1985-01-01

A preliminary result concerning the rigidity dependence of the longer-term solar cycle modulation is reported. The long-term modulation, using monthly mean intensities and referred to November 1977 as a normalizing level, appear to be in accordance with the exponent gamma = 1, provided only Brisbane and Hobart data are used. Darwin data do not conform to this pattern except perhaps during the early years of the cycle until about the end of 1980, since when the Darwin long-term intensity has been largely steady, apart from Forbush-type decreases and the as yet unidentified vector from the observed SI vector. The true SI vector of galactic origin can be obtained. The resultant vector has the amplitude of 0.031% and the phase of 2.3h. The present result seems to be consistent with those so far reported.

Beryllium sensitization and disease among long-term and short-term workers in a beryllium ceramics plant.

PubMed

Henneberger, P K; Cumro, D; Deubner, D D; Kent, M S; McCawley, M; Kreiss, K

2001-04-01

Workers at a beryllium ceramics plant were tested for beryllium sensitization and disease in 1998 to determine whether the plant-wide prevalence of sensitization and disease had declined since the last screening in 1992; an elevated prevalence was associated with specific processes or with high exposures; exposure-response relationships differed for long-term workers hired before the last plant-wide screening and short-term workers hired since then. Current workers were asked to complete a questionnaire and to provide blood for the beryllium lymphocyte proliferation test (BeLPT). Those with an abnormal BeLPT were classified as sensitized, and were offered clinical evaluation for beryllium disease. Task- and time-specific measurements of airborne beryllium were combined with individual work histories to compute mean, cumulative, and peak beryllium exposures for each worker. The 151 participants represented 90% of 167 eligible workers. Fifteen (9.9% of 151) had an abnormal BeLPT and were split between long-term workers (8/77 = 10.4%) and short-term workers (7/74 = 9.5%). Beryllium disease was detected in 9.1% (7/77) of long-term workers but in only 1.4% (1/74) of short-term workers (P = 0.06), for an overall prevalence of 5.3% (8/151). These prevalences were similar to those observed in the earlier survey. The prevalence of sensitization was elevated in 1992 among machinists, and was still elevated in 1998 among long-term workers (7/40 = 18%) but not among short-term workers (2/36 = 6%) with machining experience. The prevalence of sensitization was also elevated in both groups of workers for the processes of lapping, forming, firing, and packaging. The data suggested a positive relationship between peak beryllium exposure and sensitization for long-term workers and between mean, cumulative, and peak exposure and sensitization for short-term workers, although these findings were not statistically significant. Long-term workers with either a high peak exposure or work

Observations of Cygnus X-2 with IUE: Ultraviolet results from a multiwavelength campaign

NASA Technical Reports Server (NTRS)

Vrtilek, S. D.; Raymond, J. C.; Garcia, M. R.; Verbunt, F.; Hasinger, Guenther; Kuerster, M.

1989-01-01

The observations of the low-mass x ray binary, Cyg X-2, taken with the International Ultraviolet Explorer (IUE) in a campaign conducted in June and October of 1988 are reported. A direct relationship between the strength of the UV continuum and line emission and the placement of the x ray spectrum in one of three branches of the so-called Z-shaped curve is found by comparison with simultaneous x ray observations. All three previously known x ray spectral states are detected; the UV continuum and line emission increase monotonically along the Z with the least emission in the horizontal branch, and the most in the flaring branch. Emission lines due to HeII, CIV, NIII, NIV, NV, SiIV, and MgII are observed.

Long term ocular and neurological involvement in severe congenital toxoplasmosis.

PubMed

Meenken, C; Assies, J; van Nieuwenhuizen, O; Holwerda-van der Maat, W G; van Schooneveld, M J; Delleman, W J; Kinds, G; Rothova, A

1995-06-01

This study was set up to determine the long term ocular and systemic sequelae in patients with severe congenital toxoplasmosis. Cross sectional and retrospective study of 17 patients with severe congenital toxoplasmosis. In addition to chorioretinitis (100%), the most common abnormal ocular features were optic nerve atrophy (83%), visual acuity of less than 0.1 (85%), strabismus, and microphthalmos. In 50% of cases we observed iridic abnormalities and about 40% developed a cataract. Overt endocrinological disease, diagnosed in five of 15 patients, included panhypopituitarism (n = 2), gonadal failure with dwarfism (n = 1), precocious puberty with dwarfism and thyroid deficiency (n = 1), and diabetes mellitus and thyroid deficiency (n = 1). The observed endocrinological involvement was associated in all cases with obstructive hydrocephalus with a dilated third ventricle and optic nerve atrophy. The recognition of long term ocular, neurological, and endocrinological sequelae of congenital toxoplasmosis is important for medical management of these severely handicapped patients.

Long term ocular and neurological involvement in severe congenital toxoplasmosis.

PubMed Central

Meenken, C; Assies, J; van Nieuwenhuizen, O; Holwerda-van der Maat, W G; van Schooneveld, M J; Delleman, W J; Kinds, G; Rothova, A

1995-01-01

AIMS--This study was set up to determine the long term ocular and systemic sequelae in patients with severe congenital toxoplasmosis. METHODS--Cross sectional and retrospective study of 17 patients with severe congenital toxoplasmosis. RESULTS--In addition to chorioretinitis (100%), the most common abnormal ocular features were optic nerve atrophy (83%), visual acuity of less than 0.1 (85%), strabismus, and microphthalmos. In 50% of cases we observed iridic abnormalities and about 40% developed a cataract. Overt endocrinological disease, diagnosed in five of 15 patients, included panhypopituitarism (n = 2), gonadal failure with dwarfism (n = 1), precocious puberty with dwarfism and thyroid deficiency (n = 1), and diabetes mellitus and thyroid deficiency (n = 1). The observed endocrinological involvement was associated in all cases with obstructive hydrocephalus with a dilated third ventricle and optic nerve atrophy. CONCLUSION--The recognition of long term ocular, neurological, and endocrinological sequelae of congenital toxoplasmosis is important for medical management of these severely handicapped patients. PMID:7626575

Long-term adherence to apomorphine infusion in patients with Parkinson disease: a 10-year observational study.

PubMed

Kimber, Thomas E; Fang, Jing; Huddy, Lynda J; Thompson, Philip D

2017-05-01

Patients with Parkinson disease (PD) commonly experience motor fluctuations and dyskinesias in response to oral dopaminergic medications. Affected patients may benefit from device-assisted therapy, such as medication infusion or deep brain stimulation surgery. This is the first Australian study of the long-term adherence to apomorphine infusion (AI) in patients with PD. To assess the adherence to AI in patients with PD in a single centre over a 10-year period and to find the reasons for discontinuation in patients who discontinued AI. This is an observational study of patients with PD treated with AI between 2004 and 2014. Outcome measures included changes in motor function and quality of life following AI, change in dose of other dopaminergic medications following AI, duration of infusion, adverse effects, reasons for cessation of AI and subsequent treatment after cessation. Mean duration of AI was 21.65 months. No patient achieved apomorphine monotherapy, and the mean reduction in the levodopa-equivalent dose of other dopaminergic medications after AI was 22.7%. The benefit of AI on motor function and quality of life was rated as 'much improved' or 'better' in 83% of patients. The most common reasons for discontinuation of AI were adverse effects and inadequate motor benefit. Most patients who discontinued AI were subsequently treated with another device-assisted therapy. AI is an effective therapy for severe motor response complications in PD, especially in the short and medium term. However, many patients cannot be maintained on AI in the longer term. © 2017 Royal Australasian College of Physicians.

Focused campaign increases activity among participants in Nature's Notebook, a citizen science project

USGS Publications Warehouse

Crimmins, Theresa M.; Weltzin, Jake F.; Rosemartin, Alyssa H.; Surina, Echo M.; Marsh, Lee; Denny, Ellen G.

2014-01-01

Citizen science projects, which engage non-professional scientists in one or more stages of scientific research, have been gaining popularity; yet maintaining participants’ activity level over time remains a challenge. The objective of this study was to evaluate the potential for a short-term, focused campaign to increase participant activity in a national-scale citizen science program. The campaign that we implemented was designed to answer a compelling scientific question. We invited participants in the phenology-observing program, Nature’s Notebook, to track trees throughout the spring of 2012, to ascertain whether the season arrived as early as the anomalous spring of 2010. Consisting of a series of six electronic newsletters and costing our office slightly more than 1 week of staff resources, our effort was successful; compared with previous years, the number of observations collected in the region where the campaign was run increased by 184%, the number of participants submitting observations increased by 116%, and the number of trees registered increased by 110%. In comparison, these respective metrics grew by 25, 55, and 44%, over previous years, in the southeastern quadrant of the United States, where no such campaign was carried out. The campaign approach we describe here is a model that could be adapted by a wide variety of programs to increase engagement and thereby positively influence participant retention.

Radio observations of GRB 100418a: Test of an energy injection model explaining long-lasting GRB afterglows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moin, A.; Wang, Z.; Chandra, P.

We present the results of our radio observational campaign of gamma-ray burst (GRB) 100418a, for which we used the Australia Telescope Compact Array, the Very Large Array, and the Very Long Baseline Array. GRB 100418a was a peculiar GRB with unusual X-ray and optical afterglow profiles featuring a plateau phase with a very shallow rise. This observed plateau phase was believed to be due to a continued energy injection mechanism that powered the forward shock, giving rise to an unusual and long-lasting afterglow. The radio afterglow of GRB 100418a was detectable several weeks after the prompt emission. We conducted long-termmore » monitoring observations of the afterglow and attempted to test the energy injection model advocating that the continuous energy injection is due to shells of material moving at a wide range of Lorentz factors. We obtained an upper limit of γ < 7 for the expansion rate of the GRB 100418a radio afterglow, indicating that the range-of-Lorentz factor model could only be applicable for relatively slow-moving ejecta. A preferred explanation could be that continued activity of the central engine may have powered the long-lasting afterglow.« less

Absorption/transmission measurements of PSAP particle-laden filters from the Biomass Burning Observation Project (BBOP) field campaign

DOE Office of Scientific and Technical Information (OSTI.GOV)

Presser, Cary; Nazarian, Ashot; Conny, Joseph M.

Absorptivity measurements with a laser-heating approach, referred to as the laser-driven thermal reactor (LDTR), were carried out in the infrared and applied at ambient (laboratory) nonreacting conditions to particle-laden filters from a three-wavelength (visible) particle/soot absorption photometer (PSAP). Here, the particles were obtained during the Biomass Burning Observation Project (BBOP) field campaign. The focus of this study was to determine the particle absorption coefficient from field-campaign filter samples using the LDTR approach, and compare results with other commercially available instrumentation (in this case with the PSAP, which has been compared with numerous other optical techniques).

Absorption/transmission measurements of PSAP particle-laden filters from the Biomass Burning Observation Project (BBOP) field campaign

DOE PAGES

Presser, Cary; Nazarian, Ashot; Conny, Joseph M.; ...

2016-12-02

Absorptivity measurements with a laser-heating approach, referred to as the laser-driven thermal reactor (LDTR), were carried out in the infrared and applied at ambient (laboratory) nonreacting conditions to particle-laden filters from a three-wavelength (visible) particle/soot absorption photometer (PSAP). Here, the particles were obtained during the Biomass Burning Observation Project (BBOP) field campaign. The focus of this study was to determine the particle absorption coefficient from field-campaign filter samples using the LDTR approach, and compare results with other commercially available instrumentation (in this case with the PSAP, which has been compared with numerous other optical techniques).

Biases in Long-term NO2 Averages Inferred from Satellite Observations Due to Cloud Selection Criteria

NASA Technical Reports Server (NTRS)

Geddes, Jeffrey A.; Murphy, Jennifer G.; O'Brien, Jason M.; Celarier, Edward A.

2012-01-01

Retrievals of atmospheric trace gas column densities from space are compromised by the presence of clouds, requiring most studies to exclude observations with significant cloud fractions in the instrument's field of view. Using NO2 observations at three ground stations representing urban, suburban, and rural environments, and tropospheric vertical column densities measured by the Ozone Monitoring Instrument (OMI) over each site, we show that the observations from space represent monthly averaged ground-level pollutant conditions well (R=0.86) under relatively cloud-free conditions. However, by analyzing the ground-level data and applying the OMI cloud fraction as a filter, we show there is a significant bias in long-term averaged NO2 as a result of removing the data during cloudy conditions. For the ground-based sites considered in this study, excluding observations on days when OMI-derived cloud fractions were greater than 0.2 causes 12:00-14:00 mean summer mixing ratios to be underestimated by 12%+/-6%, 20%+/-7%, and 40%+/-10% on average (+/-1 standard deviation) at the urban, suburban, and rural sites respectively. This bias was investigated in particular at the rural site, a region where pollutant transport is the main source of NO2, and where longterm observations of NOy were also available. Evidence of changing photochemical conditions and a correlation between clear skies and the transport of cleaner air masses play key roles in explaining the bias. The magnitude of a bias is expected to vary from site to site depending on meteorology and proximity to NOx sources, and decreases when longer averaging times of ground station data (e.g. 24-h) are used for the comparison.

Deficits in long-term recognition memory reveal dissociated subtypes in congenital prosopagnosia.

PubMed

Stollhoff, Rainer; Jost, Jürgen; Elze, Tobias; Kennerknecht, Ingo

2011-01-25

The study investigates long-term recognition memory in congenital prosopagnosia (CP), a lifelong impairment in face identification that is present from birth. Previous investigations of processing deficits in CP have mostly relied on short-term recognition tests to estimate the scope and severity of individual deficits. We firstly report on a controlled test of long-term (one year) recognition memory for faces and objects conducted with a large group of participants with CP. Long-term recognition memory is significantly impaired in eight CP participants (CPs). In all but one case, this deficit was selective to faces and didn't extend to intra-class recognition of object stimuli. In a test of famous face recognition, long-term recognition deficits were less pronounced, even after accounting for differences in media consumption between controls and CPs. Secondly, we combined test results on long-term and short-term recognition of faces and objects, and found a large heterogeneity in severity and scope of individual deficits. Analysis of the observed heterogeneity revealed a dissociation of CP into subtypes with a homogeneous phenotypical profile. Thirdly, we found that among CPs self-assessment of real-life difficulties, based on a standardized questionnaire, and experimentally assessed face recognition deficits are strongly correlated. Our results demonstrate that controlled tests of long-term recognition memory are needed to fully assess face recognition deficits in CP. Based on controlled and comprehensive experimental testing, CP can be dissociated into subtypes with a homogeneous phenotypical profile. The CP subtypes identified align with those found in prosopagnosia caused by cortical lesions; they can be interpreted with respect to a hierarchical neural system for face perception.

Deficits in Long-Term Recognition Memory Reveal Dissociated Subtypes in Congenital Prosopagnosia

PubMed Central

Stollhoff, Rainer; Jost, Jürgen; Elze, Tobias; Kennerknecht, Ingo

2011-01-01

The study investigates long-term recognition memory in congenital prosopagnosia (CP), a lifelong impairment in face identification that is present from birth. Previous investigations of processing deficits in CP have mostly relied on short-term recognition tests to estimate the scope and severity of individual deficits. We firstly report on a controlled test of long-term (one year) recognition memory for faces and objects conducted with a large group of participants with CP. Long-term recognition memory is significantly impaired in eight CP participants (CPs). In all but one case, this deficit was selective to faces and didn't extend to intra-class recognition of object stimuli. In a test of famous face recognition, long-term recognition deficits were less pronounced, even after accounting for differences in media consumption between controls and CPs. Secondly, we combined test results on long-term and short-term recognition of faces and objects, and found a large heterogeneity in severity and scope of individual deficits. Analysis of the observed heterogeneity revealed a dissociation of CP into subtypes with a homogeneous phenotypical profile. Thirdly, we found that among CPs self-assessment of real-life difficulties, based on a standardized questionnaire, and experimentally assessed face recognition deficits are strongly correlated. Our results demonstrate that controlled tests of long-term recognition memory are needed to fully assess face recognition deficits in CP. Based on controlled and comprehensive experimental testing, CP can be dissociated into subtypes with a homogeneous phenotypical profile. The CP subtypes identified align with those found in prosopagnosia caused by cortical lesions; they can be interpreted with respect to a hierarchical neural system for face perception. PMID:21283572

The ESA SSA NEO Coordination Centre contribution to NEO hazard monitoring and observational campaigns

NASA Astrophysics Data System (ADS)

Micheli, Marco; Borgia, Barbara; Drolshagen, Gerhard; Koschny, Detlef; Perozzi, Ettore

2015-08-01

The NEO Coordination Centre (NEOCC) has recently been established in Frascati, near Rome, within the framework of the ESA Space Situational Awareness (SSA) Programme. Among its tasks is the coordination of observational activities related to the NEO hazard, and the distribution of relevant and up-to-date information on NEOs to both the scientific community and general users through its web portal (http://neo.ssa.esa.int).On the observational side, the NEOCC is linked to an increasingly large worldwide network of collaborating observatories, ranging from amateurs observers to large professional telescopes. The Centre organizes observation campaigns, alerting the network to suggest urgent or high-priority observations, and providing them with observational support.The NEOCC is also directly obtaining astrometric observations of high-priority targets, especially Virtual Impactors (VIs), on challenging objects as faint as magnitude 26.5, thanks to successful collaborations with ESO VLT in Chile and the INAF-sponsored LBT in Arizona. In addition, the Centre carries out regular monthly runs dedicated to NEO follow-up, recovery and survey activities with the 1-meter ESA OGS telescope in Tenerife.From a service perspective, the NEO System hosted at the NEOCC collects data and information on NEOs produced by various European services (e.g. NEODyS, EARN) and makes them available to a variety of users, with a particular focus on objects with possible collision solutions with the Earth. Among the tools provided through the web portal are the Risk List (a table of all known NEOs with impact solutions), a table of recent and upcoming close approaches, a database of physical properties of NEOs and the so-called Priority List, which allows observers to identify NEOs in most urgent need of observations, and prioritise their observational activities accordingly.The results of our recent observation campaigns and some major recent improvements to the NEO System will presented and

Early nutrition and health: short- and long-term outcomes.

PubMed

Gruszfeld, Dariusz; Socha, Piotr

2013-01-01

Maternal diet, nutritional status during pregnancy, and the early diet of the offspring play an important role in later health. The short- and long-term outcomes of early nutrition have been extensively studied in recent decades. One of the most commonly investigated nutritional interventions is breastfeeding, which is associated with a number of positive short- and long-term outcomes. A short-term effect of breastfeeding is reduced morbidity and mortality in children from poor living conditions and in preterm infants. Breastfeeding is associated with better cognitive development and also has a long-term protective effect on obesity risk, prevalence of type 2 diabetes, and a lowering effect on blood pressure. Selected nutrients have undergone extensive investigation to show their role in disease prevention or improved development, e.g. protein intake in infancy seems to be associated with a later risk of obesity or docosahexaenoic acid supplementation has a positive impact on cognitive function. Another consideration is the fast catch-up growth in small for gestational age infants as an important factor associated with adult risk of cardiovascular problems. On the other hand, high protein and energy intake seems to be positively associated with some indicators of cognitive development. Most of the evidence comes from observational studies that cannot exclude potential confounders. Animal studies demonstrate causality but should not be directly extrapolated to humans. The number of randomized controlled studies is increasing but long-term follow-ups are necessary to obtain convincing results. The majority of these trials compare different infant formula compositions and macro- or micronutrient supplementation. One of the major questions is to define a critical (or opportunity) window and a mechanism of nutritional influence on several health outcomes. Copyright © 2013 S. Karger AG, Basel.

Long-term dizziness handicap in patients with vestibular schwannoma: a multicenter cross-sectional study.

PubMed

Carlson, Matthew L; Tveiten, Øystein Vesterli; Driscoll, Colin L; Neff, Brian A; Shepard, Neil T; Eggers, Scott D; Staab, Jeffrey P; Tombers, Nicole M; Goplen, Frederik K; Lund-Johansen, Morten; Link, Michael J

2014-12-01

(1) To characterize long-term dizziness following observation, microsurgery, and stereotactic radiosurgery (SRS) for small to medium-sized vestibular schwannoma (VS) using a validated self-assessment inventory; and (2) to identify clinical variables associated with long-term dizziness handicap. Cross-sectional observational study. Two independent tertiary academic referral centers: one located in the United States and one in Norway. All patients with sporadic VS of less than 3 cm who underwent primary microsurgery, SRS, or observation between 1998 and 2008 were identified. Subjects were surveyed via a postal questionnaire using the Dizziness Handicap Inventory (DHI) and a VS symptom questionnaire. The overall survey response rate was 79%. A total of 538 respondents (mean age, 64 years; 56% female) were analyzed, and the mean time interval between treatment and survey was 7.7 years. Pretreatment variables associated with greater dizziness handicap included female sex, older age, larger tumor size, preexisting diagnosis of headache or migraine, and symptoms of dizziness predating treatment. Significant posttreatment features strongly associated with poor long-term DHI scores included frequency and severity of ongoing headache. On multivariable analysis, treatment modality did not influence long-term dizziness handicap. At a mean of approximately 8 years following treatment, over half of patients with VS reported ongoing dizziness. The authors have identified several baseline features that may help predict the risk of lasting dizziness. Treatment modality does not appear to influence long-term DHI score. We found a strong association between posttreatment headache and poor dizziness handicap. Future study is needed to further define this relationship. © American Academy of Otolaryngology—Head and Neck Surgery Foundation 2014.

Searching for signposts: Adaptive planning thresholds in long-term water supply projections for the Western U.S.

NASA Astrophysics Data System (ADS)

Robinson, B.; Herman, J. D.

2017-12-01

Long-term water supply planning is challenged by highly uncertain streamflow projections across climate models and emissions scenarios. Recent studies have devised infrastructure and policy responses that can withstand or adapt to an ensemble of scenarios, particularly those outside the envelope of historical variability. An important aspect of this process is whether the proposed thresholds for adaptation (i.e., observations that trigger a response) truly represent a trend toward future change. Here we propose an approach to connect observations of annual mean streamflow with long-term projections by filtering GCM-based streamflow ensembles. Visualizations are developed to investigate whether observed changes in mean annual streamflow can be linked to projected changes in end-of-century mean and variance relative to the full ensemble. A key focus is identifying thresholds that point to significant long-term changes in the distribution of streamflow (+/- 20% or greater) as early as possible. The analysis is performed on 87 sites in the Western United States, using streamflow ensembles through 2100 from a recent study by the U.S. Bureau of Reclamation. Results focus on three primary questions: (1) how many years of observed data are needed to identify the most extreme scenarios, and by what year can they be identified? (2) are these features different between sites? and (3) using this analysis, do observed flows to date at each site point to significant long-term changes? This study addresses the challenge of severe uncertainty in long-term streamflow projections by identifying key thresholds that can be observed to support water supply planning.

42 CFR 412.536 - Special payment provisions for long-term care hospitals and satellites of long-term care...

Code of Federal Regulations, 2010 CFR

2010-10-01

... December 29, 2007, was co-located with an entity that is a provider-based, off-campus location of a... hospital or the satellite facility from any individual hospital not co-located with the long-term care... from any individual hospital not co-located with the long-term care hospital or with the satellite of a...

Short-term and long-term treatment outcomes with Class III activator

PubMed Central

Ryu, Hyo-kyung; Chong, Hyun-Jeong; An, Ki-Yong

2015-01-01

Objective The purpose of this retrospective study was to investigate short-term and long-term skeletodental outcomes of Class III activator treatment. Methods A Class III activator treatment group (AG) comprised of 22 patients (9 boys, 13 girls) was compared with a Class III control group (CG) comprised of 17 patients (6 boys, 11 girls). The total treatment period was divided into three stages; the initial stage (T1), the post-activator treatment or post-mandibular growth peak stage (T2), and the long-term follow-up stage (T3). Cephalometric changes were evaluated statistically via the Mann-Whitney U-test and the Friedman test. Results The AG exhibited significant increases in the SNA angle, ANB angle, Wits appraisal, A point-N perpendicular, Convexity of A point, and proclination of the maxillary incisors, from T1 to T2. In the long-term follow-up (T1-T3), the AG exhibited significantly greater increases in the ANB angle, Wits appraisal, and Convexity of A point than the CG. Conclusions Favorable skeletal outcomes induced during the Class III activator treatment period were generally maintained until the long-term follow-up period of the post-mandibular growth peak stage. PMID:26445717

Hippocampal Focal Knockout of CBP Affects Specific Histone Modifications, Long-Term Potentiation, and Long-Term Memory

PubMed Central

Barrett, Ruth M; Malvaez, Melissa; Kramar, Eniko; Matheos, Dina P; Arrizon, Abraham; Cabrera, Sara M; Lynch, Gary; Greene, Robert W; Wood, Marcelo A

2011-01-01

To identify the role of the histone acetyltransferase (HAT) CREB-binding protein (CBP) in neurons of the CA1 region of the hippocampus during memory formation, we examine the effects of a focal homozygous knockout of CBP on histone modifications, gene expression, synaptic plasticity, and long-term memory. We show that CBP is critical for the in vivo acetylation of lysines on histones H2B, H3, and H4. CBP's homolog p300 was unable to compensate for the loss of CBP. Neurons lacking CBP maintained phosphorylation of the transcription factor CREB, yet failed to activate CREB:CBP-mediated gene expression. Loss of CBP in dorsal CA1 of the hippocampus resulted in selective impairments to long-term potentiation and long-term memory for contextual fear and object recognition. Together, these results suggest a necessary role for specific chromatin modifications, selectively mediated by CBP in the consolidation of memories. PMID:21508930

[Long-term service-dependent patients in mental health care: connection to urbanisation].

PubMed

Dieperink, C J; Pijl, Y J; Mulder, C L; van Os, J; Drukker, M

2008-01-01

In view of the increased rate of psychiatric morbidity in urban areas there is likely to be a relation between urbanisation and the extent to which patients use the care services. It is not yet known whether this relation is particularly strong in the case of long-term service-dependent patients with mental health problems. To investigate the possible relation between the prevalence of long-term service-dependent patients and the degree of urbanisation and to find out if there are differences in the strength of this relation in the case of different types of long-term patients and between these patients and other psychiatric patients. Data were collected from three psychiatric case registers and from the Statistics Netherlands (cbs). Distinctions were made between three types of long-term patients: 'long stay', 'residential & outpatient' and 'outpatient'. The population was divided into five categories according to the degree of urbanisation in the area of residence. Data were analysed using Poisson regression analysis, corrected for differences in age, sex, marital status and the amount of care available. The incidence rate ratios for the categories 'long stay', 'residential & outpatient' and 'outpatient' and for other patients were significantly higher for each category of urbanisation than for non-urbanised municipalities. There was also a significant positive linear relation. For long stay patients no significant relation was found with the degree of urbanisation. The total ratios for long-term patients were higher than the ratios for other types of patients. The ratios for residential and outpatient were higher than the ratios for outpatient. The prevalence of long-term service-dependent patients in mental health care increases with the degree of urbanisation and this increase is stronger than the increase observed for other patients. Furthermore, the relation with urbanisation for the category residential and outpatient is stronger for the category

Long-term record of top-of-atmosphere albedo generated from AVHRR data

NASA Astrophysics Data System (ADS)

Song, Z.

2017-12-01

Top-of-Atmosphere (TOA) albedo is a fundamental component of Earth's energy budget. Previously, long-term accurate TOA albedo products did not exist due to the lack of stable broadband observations. With a new albedo estimation methodology based on multispectral observations, TOA albedo since 1981 has been retrieved using data from the Advanced Very High Resolution Radiometer (AVHRR), which provides the longest record of satellite observations across the globe. To develop the long-term TOA albedo record, the instantaneous TOA albedo was calculated by the direct estimation method, which was built on training data pairs from coincident AVHRR TOA reflectance and Moderate Resolution Imaging Spectroradiometer (MODIS) TOA albedo. The instantaneous TOA albedo was then converted to daily mean and monthly mean albedo based on the diurnal curves from geostationary satellites. The TOA albedo results (AVHRR-TAL) were compared with Clouds and the Earth's Radiant Energy System (CERES) flux products for 2007. The monthly mean AVHRR-TAL agreed well with the CERES products, with a root mean square difference (RMSD) of 0.032 and a bias of 0.013. In addition, AVHRR-TAL showed similar seasonal variations to those seen in the CERES products. Further analysis on long-term time series showed good consistency between the two datasets (R2 > 0.95 and relative RMSD < 4%) from 2000 to 2015. Although some calibration issues remain to be solved, our datasets show the potential ability to observe the global TOA albedo from 1981 to the present.

[Psychosocial issues of long-term cancer survivors].

PubMed

Weis, J; Faller, H

2012-04-01

Although cancer incidence rates are increasing, recent statistical studies suggest that cancer patients are showing higher cure rates as well as improved overall survival rates for most cancer locations. These advances are explained by improved strategies in early diagnoses as well as improved cancer therapies. Therefore, the number of long-term cancer survivors has also increased, but only few studies, especially within the last years, have focused on psychosocial issues of this subgroup. Some studies show that overall quality of life of long-term cancer survivors is quite high and comparable to that of the normal population. Nevertheless, a substantial percentage of former patients shows reduced quality of life and suffers from various sequelae of cancer and its treatment. This review focuses on the most common psychosocial issue of long-term survivors such as reduced psychological wellbeing, neuropsychological deficits and cancer-related fatigue syndrome. Finally, recommendations for problem-oriented interventions as well as improvement of psychosocial care of long-term survivors are given.

Micro patterned surfaces allow long-term digital holographic microscopy live cell imaging

NASA Astrophysics Data System (ADS)

Mues, Sarah; Lilge, Inga; Schönherr, Holger; Kemper, Björn; Schnekenburger, Jürgen

2017-07-01

During long-term imaging, cells move out of the field of view. We have generated functionalized substrates containing rectangular areas, which were capable in keeping cells over the whole observation period.

A security/safety survey of long term care facilities.

PubMed

Acorn, Jonathan R

2010-01-01

What are the major security/safety problems of long term care facilities? What steps are being taken by some facilities to mitigate such problems? Answers to these questions can be found in a survey of IAHSS members involved in long term care security conducted for the IAHSS Long Term Care Security Task Force. The survey, the author points out, focuses primarily on long term care facilities operated by hospitals and health systems. However, he believes, it does accurately reflect the security problems most long term facilities face, and presents valuable information on security systems and practices which should be also considered by independent and chain operated facilities.

Long-Term Care Financing: Lessons From France

PubMed Central

Doty, Pamela; Nadash, Pamela; Racco, Nathalie

2015-01-01

Context An aging population leads to a growing demand for long-term services and supports (LTSS). In 2002, France introduced universal, income-adjusted, public long-term care coverage for adults 60 and older, whereas the United States funds means-tested benefits only. Both countries have private long-term care insurance (LTCI) markets: American policies create alternatives to out-of-pocket spending and protect purchasers from relying on Medicaid. Sales, however, have stagnated, and the market's viability is uncertain. In France, private LTCI supplements public coverage, and sales are growing, although its potential to alleviate the long-term care financing problem is unclear. We explore whether France's very different approach to structuring public and private financing for long-term care could inform the United States’ long-term care financing reform efforts. Methods We consulted insurance experts and conducted a detailed review of public reports, academic studies, and other documents to understand the public and private LTCI systems in France, their advantages and disadvantages, and the factors affecting their development. Findings France provides universal public coverage for paid assistance with functional dependency for people 60 and older. Benefits are steeply income adjusted and amounts are low. Nevertheless, expenditures have exceeded projections, burdening local governments. Private supplemental insurance covers 11% of French, mostly middle-income adults (versus 3% of Americans 18 and older). Whether policyholders will maintain employer-sponsored coverage after retirement is not known. The government's interest in pursuing an explicit public/private partnership has waned under President François Hollande, a centrist socialist, in contrast to the previous center-right leader, President Nicolas Sarkozy, thereby reducing the prospects of a coordinated public/private strategy. Conclusions American private insurers are showing increasing interest in long-term

Long-Term Memory and Learning

ERIC Educational Resources Information Center

Crossland, John

2011-01-01

The English National Curriculum Programmes of Study emphasise the importance of knowledge, understanding and skills, and teachers are well versed in structuring learning in those terms. Research outcomes into how long-term memory is stored and retrieved provide support for structuring learning in this way. Four further messages are added to the…

Aerosol Optical Thickness comparisons between NASA LaRC Airborne HSRL and AERONET during the DISCOVER-AQ field campaigns

NASA Astrophysics Data System (ADS)

Scarino, A. J.; Ferrare, R. A.; Burton, S. P.; Hostetler, C. A.; Hair, J. W.; Rogers, R. R.; Berkoff, T.; Cook, A. L.; Harper, D. B.; Hoff, R. M.; Holben, B. N.; Schafer, J.; McGill, M. J.; Yorks, J. E.; Lantz, K. O.; Michalsky, J. J.; Hodges, G.

2013-12-01

The first- and second-generation NASA airborne High Spectral Resolution Lidars (HSRL-1 and HSRL-2) have been deployed on board the NASA Langley Research Center King Air aircraft during the Deriving Information on Surface Conditions from Column and VERtically Resolved Observations Relevant to Air Quality (DISCOVER-AQ) field campaigns. These included deployments during July 2011 over Washington, D.C. and Baltimore, MD and during January and February 2013 over the San Joaquin Valley (SJV) of California and also a scheduled deployment during September 2013 over Houston, TX. Measurements of aerosol extinction, backscatter, and depolarization are available from both HSRL-1 and HSRL-2 in coordination with other participating research aircraft and ground sites. These measurements constitute a diverse data set for use in characterizing the spatial and temporal distribution of aerosols, aerosol optical thickness (AOT), as well as the Mixing Layer Height (MLH). HSRL AOT is compared to AOT measured by the Distributed Regional Aerosol Gridded Observation Networks (DRAGON) and long-term AERONET sites. For the 2011 campaign, comparisons of AOT at 532nm between HSRL-1 and AERONET showed excellent agreement (r = 0.98, slope = 1.01, intercept = 0.037) when the King Air flights were within 2.5 km of the ground site and 10 min from the retrieval time. The comparison results are similar for the 2013 DISCOVER-AQ campaign in the SJV. Additional ground-based (MPL) and airborne (CPL) lidar data were used to help screen for clouds in the AERONET observations during the SJV portion. AOT values from a Multi-Filter Rotating Shadowband Radiometer (MFRSR) located at the Porterville, CA site during the SJV campaign are also compared to HSRL-2 AOT. Lastly, using the MLH retrieved from HSRL aerosol backscatter profiles, we describe the distribution of AOT relative to the MLH.

Long-term mortality after community-acquired pneumonia--impacts of diabetes and newly discovered hyperglycaemia: a prospective, observational cohort study.

PubMed

Koskela, Heikki O; Salonen, Päivi H; Romppanen, Jarkko; Niskanen, Leo

2014-08-21

Community-acquired pneumonia is associated with a significant long-term mortality after initial recovery. It has been acknowledged that additional research is urgently needed to examine the contributors to this long-term mortality. The objective of the present study was to assess whether diabetes or newly discovered hyperglycaemia during pneumonia affects long-term mortality. A prospective, observational cohort study. A single secondary centre in eastern Finland. 153 consecutive hospitalised patients who survived at least 30 days after mild-to-moderate community-acquired pneumonia. Plasma glucose levels were recorded seven times during the first day on the ward. Several possible confounders were also recorded. The surveillance status and causes of death were recorded after median of 5 years and 11 months. In multivariate Cox regression analysis, a previous diagnosis of diabetes among the whole population (adjusted HR 2.84 (1.35-5.99)) and new postprandial hyperglycaemia among the non-diabetic population (adjusted HR 2.56 (1.04-6.32)) showed independent associations with late mortality. New fasting hyperglycaemia was not an independent predictor. The mortality rates at the end of follow-up were 54%, 37% and 10% among patients with diabetes, patients without diabetes with new postprandial hyperglycaemia and patients without diabetes without postprandial hyperglycaemia, respectively (p<0.001). The underlying causes of death roughly mirrored those in the Finnish general population with a slight excess in mortality due to chronic respiratory diseases. Pneumonia was the immediate cause of death in just 8% of all late deaths. A previous diagnosis of diabetes and newly discovered postprandial hyperglycaemia increase the risk of death for several years after community-acquired pneumonia. As the knowledge about patient subgroups with an increased late mortality risk is gradually gathering, more studies are needed to evaluate the possible postpneumonia interventions to

Long-term mortality after community-acquired pneumonia—impacts of diabetes and newly discovered hyperglycaemia: a prospective, observational cohort study

PubMed Central

Koskela, Heikki O; Salonen, Päivi H; Romppanen, Jarkko; Niskanen, Leo

2014-01-01

Objectives Community-acquired pneumonia is associated with a significant long-term mortality after initial recovery. It has been acknowledged that additional research is urgently needed to examine the contributors to this long-term mortality. The objective of the present study was to assess whether diabetes or newly discovered hyperglycaemia during pneumonia affects long-term mortality. Design A prospective, observational cohort study. Setting A single secondary centre in eastern Finland. Participants 153 consecutive hospitalised patients who survived at least 30 days after mild-to-moderate community-acquired pneumonia. Interventions Plasma glucose levels were recorded seven times during the first day on the ward. Several possible confounders were also recorded. The surveillance status and causes of death were recorded after median of 5 years and 11 months. Results In multivariate Cox regression analysis, a previous diagnosis of diabetes among the whole population (adjusted HR 2.84 (1.35–5.99)) and new postprandial hyperglycaemia among the non-diabetic population (adjusted HR 2.56 (1.04–6.32)) showed independent associations with late mortality. New fasting hyperglycaemia was not an independent predictor. The mortality rates at the end of follow-up were 54%, 37% and 10% among patients with diabetes, patients without diabetes with new postprandial hyperglycaemia and patients without diabetes without postprandial hyperglycaemia, respectively (p<0.001). The underlying causes of death roughly mirrored those in the Finnish general population with a slight excess in mortality due to chronic respiratory diseases. Pneumonia was the immediate cause of death in just 8% of all late deaths. Conclusions A previous diagnosis of diabetes and newly discovered postprandial hyperglycaemia increase the risk of death for several years after community-acquired pneumonia. As the knowledge about patient subgroups with an increased late mortality risk is gradually gathering

Long-Term Effectiveness of Adalimumab in Patients with Rheumatoid Arthritis: An Observational Analysis from the Corrona Rheumatoid Arthritis Registry.

PubMed

Pappas, Dimitrios A; Kremer, Joel M; Griffith, Jenny; Reed, George; Salim, Bob; Karki, Chitra; Garg, Vishvas

2017-12-01

Current recommendations for the management of rheumatoid arthritis (RA) focus on a treat-to-target approach with the objective of maximizing long-term health-related quality-of-life in patients with RA. Published studies from randomized clinical trials have reported limited data regarding the long-term efficacy and safety of adalimumab in patients with RA. This study aims to evaluate the long-term (10+ years) persistency and effectiveness of adalimumab in patients with RA in a real-world setting. Included in this study were biologic-naïve adults with RA initiating adalimumab during follow-up enrolled in the Corrona RA registry. More than 10 years of data on persistency of adalimumab and rheumatologist-supplied reasons for discontinuation were examined. Among patients who persisted on adalimumab over the years, clinical [e.g., clinical disease activity index scores (CDAI), physician global assessment, tender joint count, and swollen joint count] and patient-reported outcomes (PRO), such as physical function, pain, fatigue, and morning stiffness, were examined. Of 1791 biologic-naive patients treated with adalimumab who had ≥1 follow-up registry visit, 64.1% were still on therapy at 1 year and 10.2% were still on therapy by the end of year 12. Among patients who persisted on adalimumab for at least 1 year (77.1% female, mean age 53.9 years), 67.0% were in low disease activity (LDA)/remission (CDAI ≤10) and had clinically meaningful improvements from baseline in all clinical assessments and PROs. Initial improvements in LDA/remission and in clinical and PRO assessments observed at year 1 were sustained in those patients who remained on adalimumab over 10 years of follow-up. Among patients who discontinued adalimumab, 61.6% were not in LDA/remission and 41.9% switched to another biologic within 12 months after discontinuing adalimumab. Real-world data demonstrate a sustained effectiveness of adalimumab in the treatment of RA for patients who remained on

Long-term care financing: options for the future.

PubMed

Mulvey, Janemarie; Li, Annelise

2002-01-01

The aging of the baby boomers will have an enormous impact on the future of long-term care costs. This article projects the magnitude of that impact, discusses sources of financing, and considers the cost and feasibility of three options for financing future long-term care services. The authors investigate the alternatives of increasing personal savings, raising payroll taxes and expanding employer-sponsored private long-term care insurance coverage, respectively.

Century long observation constrained global dynamic downscaling and hydrologic implication

NASA Astrophysics Data System (ADS)

Kim, H.; Yoshimura, K.; Chang, E.; Famiglietti, J. S.; Oki, T.

2012-12-01

It has been suggested that greenhouse gas induced warming climate causes the acceleration of large scale hydrologic cycles, and, indeed, many regions on the Earth have been suffered by hydrologic extremes getting more frequent. However, historical observations are not able to provide enough information in comprehensive manner to understand their long-term variability and/or global distributions. In this study, a century long high resolution global climate data is developed in order to break through existing limitations. 20th Century Reanalysis (20CR) which has relatively low spatial resolution (~2.0°) and longer term availability (140 years) is dynamically downscaled into global T248 (~0.5°) resolution using Experimental Climate Prediction Center (ECPC) Global Spectral Model (GSM) by spectral nudging data assimilation technique. Also, Global Precipitation Climatology Centre (GPCC) and Climate Research Unit (CRU) observational data are adopted to reduce model dependent uncertainty. Downscaled product successfully represents realistic geographical detail keeping low frequency signal in mean state and spatiotemporal variability, while previous bias correction method fails to reproduce high frequency variability. Newly developed data is used to investigate how long-term large scale terrestrial hydrologic cycles have been changed globally and how they have been interacted with various climate modes, such as El-Niño Southern Oscillation (ENSO) and Atlantic Multidecadal Oscillation (AMO). As a further application, it will be used to provide atmospheric boundary condition of multiple land surface models in the Global Soil Wetness Project Phase 3 (GSWP3).

VizieR Online Data Catalog: M67 variable stars from Kepler/K2-Campaign-5 (Gonzalez, 2016)

NASA Astrophysics Data System (ADS)

Gonzalez, G.

2017-06-01

M 67 was observed continuously between 2015 April 27 and July 10 during the Kepler/K2-Campaign-5 (hereafter, 'Campaign-5 field'). It includes 28 850 long-cadence, 204 short-cadence, and several other special targets. Several data products for the Campaign-5 field were released to the public on the NASA Barbara A. Mikulski Archive for Space Telescopes (MAST) website on 2015 October 30 (https://archive.stsci.edu/k2/). We downloaded tar files containing all the long-cadence light-curve (CLC) files of the Campaign-5 targets from the MAST archive. In addition, we downloaded the comprehensive K2 input catalogue (EPIC) for the Campaign-5 field. We supplemented the NASA K2 data with ground-based data, of which Nardiello et al. (2016, Cat. J/MNRAS/455/2337) is our primary source. Nardiello et al. (2016, Cat. J/MNRAS/455/2337) list the positions and white-light magnitudes for 6905 objects in the M 67 field, but they only list BVRI magnitudes, proper motions and membership probabilities for a subset of this large sample. Cross-referencing (using coordinates) the Campaign-5 input catalogue with the Nardiello et al. (2016, Cat. J/MNRAS/455/2337) catalogue resulted in 3201 matches. Of these, 639 have light curves available in the MAST Campaign-5 archive. This will be the working sample. (1 data file).

Antibiotic Use and Need for Antimicrobial Stewardship in Long-Term Care.

PubMed

Wu, Lisa Dong-Ying; Walker, Sandra A N; Elligsen, Marion; Palmay, Lesley; Simor, Andrew; Daneman, Nick

2015-01-01

Antimicrobial stewardship may be important in long-term care facilities because of unnecessary or inappropriate antibiotic use observed in these residents, coupled with their increased vulnerability to health care-associated infections. To assess antibiotic use in a long-term care facility in order to identify potential antimicrobial stewardship needs. A retrospective descriptive study was conducted at the Veterans Centre, a long-term care facility at Sunnybrook Health Sciences Centre, Toronto, Ontario. All residents taking one or more antibiotics (n = 326) were included as participants. Antibiotic-use data for patients residing in the facility between April 1, 2011, and March 31, 2012, were collected and analyzed. Totals of 358 patient encounters, 835 antibiotic prescriptions, and 193 positive culture results were documented during the study period. For 36% (302/835) of antibiotic prescriptions, the duration was more than 7 days. Cephalosporins (30%; 251/835) and fluoroquinolones (28%; 235/835) were the most frequently prescribed antibiotic classes. Urine was the most common source of samples for culture (60%; 116/193). Characteristics of antimicrobial use at this long-term care facility that might benefit from further evaluation included potentially excessive use of fluoroquinolones and cephalosporins and potentially excessive duration of antibiotic use for individual patients.

Role of calcitonin gene-related peptide in cardioprotection of short-term and long-term exercise preconditioning.

PubMed

Sun, Xiao-Juan; Pan, Shan-Shan

2014-07-01

To examine the role of calcitonin gene-related peptide (CGRP) in cardioprotection of short-term and long-term exercise preconditioning (EP). Male Sprague-Dawley rats were, respectively, subjected to continuous intermittent treadmill training 3 days or 3 weeks as short-term or long-term EP protocols. The myocardial injury induced by isoproterenol (ISO) was performed 24 hours after short-term and long-term EP. The myocardial injury was evaluated in terms of the serum cardiac troponin levels and the hematoxylin-basic fuchsin-picric acid staining. Additionally, serum CGRP levels, CGRP expression in the dorsal root ganglion (DRG), and heart were analyzed as possible mechanisms to explain short-term and long-term EP-induced cardioprotection. Both short-term and long-term EP markedly attenuated the isoproterenol-induced myocardial ischemia with lower serum cardiac troponin levels. Short-term EP does not alter serum CGRP levels and CGRP expression in the DRG and heart. Long-term EP significantly increases serum CGRP levels and CGRP expression in the DRG and heart. The results indicate that short-term EP does not increase the synthesis and release of CGRP. Therefore, the cardioprotective effect of short-term EP does not involve CGRP adaptation. Furthermore, long-term EP increases CGRP synthesis in the DRG and promotes CGRP release in the blood and heart. Hence, CGRP may play an important role in the cardioprotective effect of long-term EP.

[Attention therapy for children - long-term affects of the ATTENTIONER].

PubMed

Jacobs, Claus; Petermann, Franz

2008-11-01

A high percentage of children are affected by attention deficit disorders. For a large proportion the cardinal symptom is inattention; in particular, deficits in selective attention prevail. The ATTENTIONER offers an effective training method for the treatment of selective attention deficit. In 2007, long-term effects of therapy were already reported by Jacobs and Petermann, who examined children ten weeks after therapy on average. In the current study three measurements were conducted: pre-intervention, post-intervention, and at follow-up ten to 76 months after post-intervention. Significant long-term effects on measures of selective attention were observed. At follow-up the majority of patients achieved average results which were not clinically relevant. For most children stable therapy effects can be achieved with the ATTENTIONER.

Assessing the Impact of Different Measurement Time Intervals on Observed Long-Term Wind Speed Trends

NASA Astrophysics Data System (ADS)

Azorin-Molina, C.; Vicente-Serrano, S. M.; McVicar, T.; Jerez, S.; Revuelto, J.; López Moreno, J. I.

2014-12-01

During the last two decades climate studies have reported a tendency toward a decline in measured near-surface wind speed in some regions of Europe, North America, Asia and Australia. This weakening in observed wind speed has been recently termed "global stilling", showing a worldwide average trend of -0.140 m s-1 dec-1 during last 50-years. The precise cause of the "global stilling" remains largely uncertain and has been hypothetically attributed to several factors, mainly related to: (i) an increasing surface roughness (i.e. forest growth, land use changes, and urbanization); (ii) a slowdown in large-scale atmospheric circulation; (iii) instrumental drifts and technological improvements, maintenance, and shifts in measurements sites and calibration issues; (iv) sunlight dimming due to air pollution; and (v) astronomical changes. This study proposed a novel investigation aimed at analyzing how different measurement time intervals used to calculate a wind speed series can affect the sign and magnitude of long-term wind speed trends. For instance, National Weather Services across the globe estimate daily average wind speed using different time intervals and formulae that may affect the trend results. Firstly, we carried out a comprehensive review of wind studies reporting the sign and magnitude of wind speed trend and the sampling intervals used. Secondly, we analyzed near-surface wind speed trends recorded at 59 land-based stations across Spain comparing monthly mean wind speed series obtained from: (a) daily mean wind speed data averaged from standard 10-min mean observations at 0000, 0700, 1300 and 1800 UTC; and (b) average wind speed of 24 hourly measurements (i.e., wind run measurements) from 0000 to 2400 UTC. Thirdly and finally, we quantified the impact of anemometer drift (i.e. bearing malfunction) by presenting preliminary results (1-year of paired measurements) from a comparison of one new anemometer sensor against one malfunctioned anenometer sensor due

Merging of long-term memories in an insect.

PubMed

Hunt, Kathryn L; Chittka, Lars

2015-03-16

Research on comparative cognition has largely focused on successes and failures of animals to solve certain cognitive tasks, but in humans, memory errors can be more complex than simple failures to retrieve information [1, 2]. The existence of various types of "false memories," in which individuals remember events that they have never actually encountered, are now well established in humans [3, 4]. We hypothesize that such systematic memory errors may be widespread in animals whose natural lifestyle involves the processing and recollection of memories for multiple stimuli [5]. We predict that memory traces for various stimuli may "merge," such that features acquired in distinct bouts of training are combined in an animal's mind, so that stimuli that have never been viewed before, but are a combination of the features presented in training, may be chosen during recall. We tested this using bumblebees, Bombus terrestris. When individuals were first trained to a solid single-colored stimulus followed by a black and white (b/w)-patterned stimulus, a subsequent preference for the last entrained stimulus was found in both short-term- and long-term-memory tests. However, when bees were first trained to b/w-patterned stimuli followed by solid single-colored stimuli and were tested in long-term-memory tests 1 or 3 days later, they only initially preferred the most recently rewarded stimulus, and then switched their preference to stimuli that combined features from the previous color and pattern stimuli. The observed merging of long-term memories is thus similar to the memory conjunction error found in humans [6]. Copyright © 2015 Elsevier Ltd. All rights reserved.

Planning long-term vegetation studies at landscape scales

USGS Publications Warehouse

Stohlgren, Thomas J.

1995-01-01

Long-term ecological research is receiving more attention now than ever before. Two recent books, Long-term Studies in Ecology: Approaches and Alternatives, edited by Gene Likens (1989), and Long-term Ecological Research: An International Perspective, edited by Paul Risser (1991), prompt the question, “Why are these books so thin?” Except for data from paleoecological, retrospective studies (see below), there are exceptionally few long-term data sets in terrestrial ecology (Strayer et al. 1986; Tilman 1989; this volume). In a sample of 749 papers published in Ecology, Tilman (1989) found that only 1.7% of the studies lasted at least five field seasons. Only one chapter in each of the review books dealt specifically with expanding both the temporal and the spatial scales of ecological research (Berkowitz et al. 1989; Magnuson et al. 1991). Judging by the growing number of landscape-scale long-term studies, however, such as the Long-Term Ecological Research (LTER) Program (Callahan 1991), the U.S. Environmental Protection Agency’s Environmental Monitoring and Assessment Program (EMAP; Palmer et al. 1991), the U.S. Army’s Land Condition-Trend Analysis (LCTA) Program (Diersing et al. 1992), and various agencies’ global change research programs (CEES 1993), there is a growing interest to expand ecological research both temporally and spatially.

Long-term Behavioral Tracking of Freely Swimming Weakly Electric Fish

PubMed Central

Jun, James J.; Longtin, André; Maler, Leonard

2014-01-01

Long-term behavioral tracking can capture and quantify natural animal behaviors, including those occurring infrequently. Behaviors such as exploration and social interactions can be best studied by observing unrestrained, freely behaving animals. Weakly electric fish (WEF) display readily observable exploratory and social behaviors by emitting electric organ discharge (EOD). Here, we describe three effective techniques to synchronously measure the EOD, body position, and posture of a free-swimming WEF for an extended period of time. First, we describe the construction of an experimental tank inside of an isolation chamber designed to block external sources of sensory stimuli such as light, sound, and vibration. The aquarium was partitioned to accommodate four test specimens, and automated gates remotely control the animals' access to the central arena. Second, we describe a precise and reliable real-time EOD timing measurement method from freely swimming WEF. Signal distortions caused by the animal's body movements are corrected by spatial averaging and temporal processing stages. Third, we describe an underwater near-infrared imaging setup to observe unperturbed nocturnal animal behaviors. Infrared light pulses were used to synchronize the timing between the video and the physiological signal over a long recording duration. Our automated tracking software measures the animal's body position and posture reliably in an aquatic scene. In combination, these techniques enable long term observation of spontaneous behavior of freely swimming weakly electric fish in a reliable and precise manner. We believe our method can be similarly applied to the study of other aquatic animals by relating their physiological signals with exploratory or social behaviors. PMID:24637642

Validation of the TOLNet lidars during SCOOP (Southern California Ozone Observation Project)

NASA Astrophysics Data System (ADS)

Leblanc, Thierry; Granados-Munoz, Maria-Jose; Strawbridge, Kevin; Senff, Chris; Langford, Andy; Berkoff, Tim; Gronoff, Guillaume; DeYoung, Russel; Carion, Bill; Chen, G.; Sullivan, John; McGee, Tom; Jonhson, M.; Kuang, S.; Newchurch, Mike

2018-04-01

Five TOLNet lidars participated to a validation campaign at the JPL-Table Mountain Facility, CA in August 2016. All lidars agreed within ±10% of each other and within ±7% of the ozonesondes. Centralized data processing was used to compare the uncertainty budgets. The results highlight the TOLNet potential to address science questions ranging from boundary layer processes to long range transport. TOLNet can now be seen as a robust network for use in field campaigns and long term monitoring.

Effect of routine repeat transurethral resection for superficial bladder cancer: a long-term observational study.

PubMed

Grimm, Marc-Oliver; Steinhoff, Christine; Simon, Xenia; Spiegelhalder, Philipp; Ackermann, Rolf; Vogeli, Thomas Alexander

2003-08-01

We determined the long-term outcome in patients with superficial bladder cancer (Ta and T1) undergoing routine second transurethral bladder tumor resection (ReTURB) in regard to recurrence and progression. We performed an inception cohort study of 124 consecutive patients with superficial bladder cancer undergoing transurethral resection and routine ReTURB (83) between November 1993 and October 1995 at a German university hospital. Immediately after transurethral resection all lesions were documented on a designed bladder map. ReTURB of the scar from initial resection and other suspicious lesions was performed at a mean of 7 weeks. Patients were followed until recurrence or death, or a minimum of 5 years. Residual tumor was found in 33% of all ReTURB cases, including 27% of Ta and 53% of T1 disease, and in 81% at the initial resection site. Five of the 83 patients underwent radical cystectomy due to ReTURB findings. The estimated risk of recurrence after years 1 to 3 was 18%, 29% and 32%, respectively. After 5 years 63% of the patients undergoing ReTURB were still disease-free (mean recurrence-free survival 62 months, median 87). Progression to muscle invasive disease was observed in only 2 patients (3%) after a mean observation of 61 months. These data suggest a favorable outcome regarding recurrence and progression in patients with superficial bladder cancer who undergo ReTURB. ReTURB is suggested at least in those at high risk when bladder preservation is intended.

PRESCRIPTION LONG-TERM OPIOID USE IN HIV-INFECTED PATIENTS

PubMed Central

Silverberg, Michael J.; Ray, G. Thomas; Saunders, Kathleen; Rutter, Carolyn M.; Campbell, Cynthia I.; Merrill, Joseph O.; Sullivan, Mark D.; Banta-Green, Caleb; Von Korff, Michael; Weisner, Constance

2011-01-01

Objectives To examine changes in use of prescription opioids for the management of chronic non-cancer pain in HIV-infected patients and to identify patient characteristics associated with long-term use. Methods Long-term prescription opioid use (i.e. 120+ days supply or 10+ prescriptions during a year) was assessed between 1997 and 2005 among 6,939 HIV-infected Kaiser Permanente members and HIV-uninfected persons in the general health plan memberships. Results In 2005, 8% of HIV+ individuals had prevalent long-term opioid use, more than double the prevalence among HIV-uninfected individuals. However, the large increases in use from 1997 to 2005 in the general population were not observed for HIV-infected individuals. The strongest associations with prevalent use among HIV-infected individuals were female gender with a prevalence ratio [PR] of 1.8 (95% CI=1.3, 2.5); Charlson comorbidity score of 2 or more (compared with a score of 0) with a PR of 1.9 (95% CI=1.4, 2.8); injection drug use history with a PR of 1.8 (95% CI=1.3, 2.6); substance use disorders with a PR of 1.8 (95% CI=1.3, 2.5). CD4, HIV RNA, and AIDS diagnoses were associated with prevalent opioid use early in the antiretroviral therapy era (1997), but not in 2005. Conclusions Long-term opioid use for chronic pain has remained stable over time for HIV patients, while use increased in the general population. The prevalence of prescribed opioids in HIV patients was highest for certain subgroups, including women, and those with a comorbidity and substance abuse history. PMID:21677568

The 2005 British Columbia Smoking Cessation Mass Media Campaign and short-term changes in smoking.

PubMed

Gagné, Lynda

2007-01-01

The objective of this study was to evaluate the impact of the 2005 British Columbia Ministry of Health Smoking Cessation Mass Media Campaign on short-term smoking behavior. National cross-sectional data are used with a quasi-experimental approach to test the impact of the campaign. Findings indicate that prevalence and average number of cigarettes smoked per day deviated upward from trend for the rest of Canada (P = .08; P = .01) but not for British Columbia. They also indicate that British Columbia smokers in lower risk groups reduced their average daily consumption of cigarettes over and above the 1999-2004 trend (-2.23; P = .10), whereas smokers in the rest of Canada did not, and that British Columbia smokers in high-risk groups did not increase their average daily consumption of cigarettes over and above the 1999-2004 trend, whereas smokers in the rest of Canada did (2.97; P = .01). The overall poorer performance of high-risk groups is attributed to high exposure to cigarette smoking, which reduces a smoker's chances of successful cessation. In particular, high-risk groups are by definition more likely to be exposed to smoking by peers, but are also less likely to work in workplaces with smoking bans, which are shown to have a substantial impact on prevalence. Results suggest that for mass media campaigns to be more effective with high-risk groups, they need to be combined with other incentives, and that more prolonged interventions should be considered.

Zeitgeists and development trends in long-term care facility design.

PubMed

Wang, Chia-Hui; Kuo, Nai-Wen

2006-06-01

Through literature analysis, in-depth interviews, and the application of the Delphi survey, this study explored long-term care resident priorities with regard to long-term care facility design in terms of both physical and psychological needs. This study further clarified changing trends in long-term care concepts; illustrated the impact that such changes are having on long-term care facility design; and summarized zeitgeists related to the architectural design of long-term care facilities. Results of our Delphi survey indicated the following top five priorities in long-term care facility design: (1) creating a home-like feeling; (2) adhering to Universal Design concepts; (3) providing well-defined private sleeping areas; (4) providing adequate social space; and (5) decentralizing residents' rooms into clusters. The three major zeitgeists related to long-term care facility design include: (1) modern long-term care facilities should abandon their traditional "hospital" image and gradually reposition facilities into homelike settings; (2) institution-based care for the elderly should be de-institutionalized under the concept of aging-in-place; and (3) living clusters, rather than traditional hospital-like wards, should be designed into long-term care facilities.

Long-term weight loss maintenance for obesity: a multidisciplinary approach

PubMed Central

Montesi, Luca; El Ghoch, Marwan; Brodosi, Lucia; Calugi, Simona; Marchesini, Giulio; Dalle Grave, Riccardo

2016-01-01

The long-term weight management of obesity remains a very difficult task, associated with a high risk of failure and weight regain. However, many people report that they have successfully managed weight loss maintenance in the long term. Several factors have been associated with better weight loss maintenance in long-term observational and randomized studies. A few pertain to the behavioral area (eg, high levels of physical activity, eating a low-calorie, low-fat diet; frequent self-monitoring of weight), a few to the cognitive component (eg, reduced disinhibition, satisfaction with results achieved, confidence in being able to lose weight without professional help), and a few to personality traits (eg, low novelty seeking) and patient–therapist interaction. Trials based on the most recent protocols of lifestyle modification, with a prolonged extended treatment after the weight loss phase, have also shown promising long-term weight loss results. These data should stimulate the adoption of a lifestyle modification-based approach for the management of obesity, featuring a nonphysician lifestyle counselor (also called “lifestyle trainer” or “healthy lifestyle practitioner”) as a pivotal component of the multidisciplinary team. The obesity physicians maintain a primary role in engaging patients, in team coordination and supervision, in managing the complications associated with obesity and, in selected cases, in the decision for drug treatment or bariatric surgery, as possible more intensive, add-on interventions to lifestyle treatment. PMID:27013897

Two Long-Term Intermittent Pulsars Discovered in the PALFA Survey

NASA Astrophysics Data System (ADS)

Lyne, A. G.; Stappers, B. W.; Freire, P. C. C.; Hessels, J. W. T.; Kaspi, V. M.; Allen, B.; Bogdanov, S.; Brazier, A.; Camilo, F.; Cardoso, F.; Chatterjee, S.; Cordes, J. M.; Crawford, F.; Deneva, J. S.; Ferdman, R. D.; Jenet, F. A.; Knispel, B.; Lazarus, P.; van Leeuwen, J.; Lynch, R.; Madsen, E.; McLaughlin, M. A.; Parent, E.; Patel, C.; Ransom, S. M.; Scholz, P.; Seymour, A.; Siemens, X.; Spitler, L. G.; Stairs, I. H.; Stovall, K.; Swiggum, J.; Wharton, R. S.; Zhu, W. W.

2017-01-01

We report the discovery of two long-term intermittent radio pulsars in the ongoing Pulsar Arecibo L-Band Feed Array survey. Following discovery with the Arecibo Telescope, extended observations of these pulsars over several years at Jodrell Bank Observatory have revealed the details of their rotation and radiation properties. PSRs J1910+0517 and J1929+1357 show long-term extreme bimodal intermittency, switching between active (ON) and inactive (OFF) emission states and indicating the presence of a large, hitherto unrecognized underlying population of such objects. For PSR J1929+1357, the initial duty cycle was fON = 0.008, but two years later, this changed quite abruptly to fON = 0.16. This is the first time that a significant evolution in the activity of an intermittent pulsar has been seen, and we show that the spin-down rate of the pulsar is proportional to the activity. The spin-down rate of PSR J1929+1357 is increased by a factor of 1.8 when it is in active mode, similar to the increase seen in the other three known long-term intermittent pulsars. These discoveries increase the number of known pulsars displaying long-term intermittency to five. These five objects display a remarkably narrow range of spin-down power (\\dot{E} ˜ {10}32 {erg} {{{s}}}-1) and accelerating potential above their polar caps. If confirmed by further discoveries, this trend might be important for understanding the physical mechanisms that cause intermittency.

How long-term dynamics of sediment subduction controls short-term dynamics of seismicity

NASA Astrophysics Data System (ADS)

Brizzi, S.; van Zelst, I.; van Dinther, Y.; Funiciello, F.; Corbi, F.

2017-12-01

Most of the world's greatest earthquakes occur along the subduction megathrust. Weak and porous sediments have been suggested to homogenize the plate interface and thereby promote lateral rupture propagation and great earthquakes. However, the importance of sediment thickness, let alone their physical role, is not yet unequivocally established. Based on a multivariate statistical analysis of a global database of 62 subduction segments, we confirm that sediment thickness is one of the key parameters controlling the maximum magnitude a megathrust can generate. Moreover, Monte Carlo simulations highlighted that the occurrence of great earthquakes on sediment-rich subduction segments is very unlikely (p-value≪0.05) related to pure chance. To understand how sediments in the subduction channel regulate earthquake size, this study extends and demystifies multivariate, spatiotemporally limited data through numerical modeling. We use the 2D Seismo-Thermo-Mechanical modeling approach to simulate both the long- and short-term dynamics of subduction and related seismogenesis (van Dinther et al., JGR, 2013). These models solve for the conservation of mass, momentum and energy using a visco-elasto-plastic rheology with rate-dependent friction. Results show that subducted sediments have a strong influence on the long-term evolution of the convergent margin. Increasing the sediment thickness on the incoming plate from 0 to 6 km causes a decrease of slab dip from 23° to 10°. This, in addition to increased radiogenic heating, extends isotherms, thereby widening the seismogenic portion of the megathrust from 80 to 150 km. Consequently, over tens of thousands of years, we observe that the maximum moment magnitude of megathrust earthquakes increases from 8.2 to 9.2 for these shallower and warmer interfaces. In addition, we observe more and larger splay faults, which could enhance vertical seafloor displacements. These results highlight the primary role of subducted sediments in

The effectiveness of vaccine day and educational interventions on influenza vaccine coverage among health care workers at long-term care facilities.

PubMed

Kimura, Akiko C; Nguyen, Christine N; Higa, Jeffrey I; Hurwitz, Eric L; Vugia, Duc J

2007-04-01

We examined barriers to influenza vaccination among long-term care facility (LTCF) health care workers in Southern California and developed simple, effective interventions to improve influenza vaccine coverage of these workers. In 2002, health care workers at LTCFs were surveyed regarding their knowledge and attitudes about influenza and the influenza vaccine. Results were used to develop 2 interventions, an educational campaign and Vaccine Day (a well-publicized day for free influenza vaccination of all employees at the worksite). Seventy facilities were recruited to participate in an intervention trial and randomly assigned to 4 study groups. The combination of Vaccine Day and an educational campaign was most effective in increasing vaccine coverage (53% coverage; prevalence ratio [PR]=1.45; 95% confidence interval [CI]=1.24, 1.71, compared with 27% coverage in the control group). Vaccine Day alone was also effective (46% coverage; PR= 1.41; 95% CI=1.17, 1.71). The educational campaign alone was not effective in improving coverage levels (34% coverage; PR=1.18; 95% CI=0.93, 1.50). Influenza vaccine coverage of LTCF health care workers can be improved by providing free vaccinations at the worksite with a well-publicized Vaccine Day.

Long Term Observations of B2 1215+30 with VERITAS

NASA Astrophysics Data System (ADS)

Aliu, E.; Archambault, S.; Arlen, T.; Aune, T.; Beilicke, M.; Benbow, W.; Bird, R.; Bouvier, A.; Buckley, J. H.; Bugaev, V.; Cesarini, A.; Ciupik, L.; Connolly, M. P.; Cui, W.; Dumm, J.; Errando, M.; Falcone, A.; Federici, S.; Feng, Q.; Finley, J. P.; Fortin, P.; Fortson, L.; Furniss, A.; Galante, N.; Gérard, L.; Gillanders, G. H.; Griffin, S.; Grube, J.; Gyuk, G.; Hanna, D.; Holder, J.; Hughes, G.; Humensky, T. B.; Kaaret, P.; Kertzman, M.; Khassen, Y.; Kieda, D.; Krawczynski, H.; Krennrich, F.; Lang, M. J.; Madhavan, A. S.; Maier, G.; Majumdar, P.; McArthur, S.; McCann, A.; Moriarty, P.; Mukherjee, R.; Nieto, D.; O'Faoláin de Bhróithe, A.; Ong, R. A.; Orr, M.; Otte, A. N.; Park, N.; Perkins, J. S.; Pohl, M.; Popkow, A.; Prokoph, H.; Quinn, J.; Ragan, K.; Reyes, L. C.; Reynolds, P. T.; Richards, G. T.; Roache, E.; Saxon, D. B.; Sembroski, G. H.; Skole, C.; Smith, A. W.; Soares-Furtado, M.; Staszak, D.; Telezhinsky, I.; Tešić, G.; Theiling, M.; Varlotta, A.; Vassiliev, V. V.; Vincent, S.; Wakely, S. P.; Weekes, T. C.; Weinstein, A.; Welsing, R.; Williams, D. A.; Zitzer, B.; VERITAS Collaboration; Böttcher, M.; Fumagalli, M.; Jadhav, J.

2013-12-01

We report on VERITAS observations of the BL Lac object B2 1215+30 between 2008 and 2012. During this period, the source was detected at very high energies (VHEs; E > 100 GeV) by VERITAS with a significance of 8.9σ and showed clear variability on timescales larger than months. In 2011, the source was found to be in a relatively bright state and a power-law fit to the differential photon spectrum yields a spectral index of 3.6 ± 0.4stat ± 0.3syst with an integral flux above 200 GeV of (8.0 ± 0.9stat ± 3.2syst) × 10-12 cm-2 s-1. No short term variability could be detected during the bright state in 2011. Multi-wavelength data were obtained contemporaneously with the VERITAS observations in 2011 and cover optical (Super-LOTIS, MDM, Swift/UVOT), X-ray (Swift/XRT), and gamma-ray (Fermi-LAT) frequencies. These were used to construct the spectral energy distribution (SED) of B2 1215+30. A one-zone leptonic model is used to model the blazar emission and the results are compared to those of MAGIC from early 2011 and other VERITAS-detected blazars. The SED can be reproduced well with model parameters typical for VHE-detected BL Lac objects.

Disability in long-term care residents explained by prevalent geriatric syndromes, not long-term care home characteristics: a cross-sectional study.

PubMed

Lane, Natasha E; Wodchis, Walter P; Boyd, Cynthia M; Stukel, Thérèse A

2017-02-10

Self-care disability is dependence on others to conduct activities of daily living, such as bathing, eating and dressing. Among long-term care residents, self-care disability lowers quality of life and increases health care costs. Understanding the correlates of self-care disability in this population is critical to guide clinical care and ongoing research in Geriatrics. This study examines which resident geriatric syndromes and chronic conditions are associated with residents' self-care disability and whether these relationships vary across strata of age, sex and cognitive status. It also describes the proportion of variance in residents' self-care disability that is explained by residents' geriatric syndromes versus long-term care home characteristics. We conducted a cross-sectional study using a health administrative cohort of 77,165 long-term care home residents residing in 614 Ontario long-term care homes. Eligible residents had their self-care disability assessed using the RAI-MDS 2.0 activities of daily living long-form score (range: 0-28) within 90 days of April 1st, 2011. Hierarchical multivariable regression models with random effects for long-term care homes were used to estimate the association between self-care disability and resident geriatric syndromes, chronic conditions and long-term care home characteristics. Differences in findings across strata of sex, age and cognitive status (cognitively intact versus cognitively impaired) were examined. Geriatric syndromes were much more strongly associated with self-care disability than chronic conditions in multivariable models. The direction and size of some of these effects were different for cognitively impaired versus cognitively intact residents. Residents' geriatric syndromes explained 50% of the variation in their self-care disability scores, while characteristics of long-term care homes explained an additional 2% of variation. Differences in long-term care residents' self-care disability are

Ms. Hisako Koyama: From Amateur Astronomer to Long-Term Solar Observer

NASA Astrophysics Data System (ADS)

Knipp, Delores; Liu, Huixin; Hayakawa, Hisashi

2017-10-01

The path to science for a girl of any nationality born in the early twentieth century was formidable-to-nonexistent. Yet paths were forged by a few. We present the little-known story of one of Japan's premier solar observers and her contribution to the world's understanding of sunspots and space weather cycles. Ms. Hisako Koyama, born in Tokyo in 1916, became a passionate amateur astronomer, a dedicated solar observer, and a long-serving staff member of the National Museum of Nature and Science, Tokyo. As a writer for amateur astronomy journals she advised many on the details and joys of sky viewing. She created a consistent, extended record of sunspots. Her multidecade archive of sunspot drawings is one of the "backbones" for the recent international recalibration of the sunspot record that provides insight into space weather reaching back to the early 1600s. We detail her contributions to the citizens of Japan as an ambassador of astronomy and her international contribution to understanding the symmetries and asymmetries of the solar cycle. We comment on the value of her continuous record of sunspots and on her tenacity in promoting a science that links to space weather.

Long-Term Monitoring of Global Climate Forcings and Feedbacks

NASA Technical Reports Server (NTRS)

Hansen, J. (Editor); Rossow, W. (Editor); Fung, I. (Editor)

1993-01-01

A workshop on Long-Term Monitoring of Global Climate Forcings and Feedbacks was held February 3-4, 1992, at NASA's Goddard Institute for Space Studies to discuss the measurements required to interpret long-term global temperature changes, to critique the proposed contributions of a series of small satellites (Climsat), and to identify needed complementary monitoring. The workshop concluded that long-term (several decades) of continuous monitoring of the major climate forcings and feedbacks is essential for understanding long-term climate change.

Long Term Care Aide/Homemaker. Resource Handbook.

ERIC Educational Resources Information Center

Illerbrun, Marley

This handbook provides basic information for preparing individuals to work as long-term care aides and homemakers. It is written both for college students in long-term care aide/homemaker programs and for individuals already employed in these occupations. Health care agencies giving orientation training for new employees and inservice training for…

Developmental Dyslexia and Explicit Long-Term Memory

ERIC Educational Resources Information Center

Menghini, Deny; Carlesimo, Giovanni Augusto; Marotta, Luigi; Finzi, Alessandra; Vicari, Stefano

2010-01-01

The reduced verbal long-term memory capacities often reported in dyslexics are generally interpreted as a consequence of their deficit in phonological coding. The present study was aimed at evaluating whether the learning deficit exhibited by dyslexics was restricted only to the verbal component of the long-term memory abilities or also involved…

78 FR 36449 - State Long-Term Care Ombudsman Program

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-18

... 0985-AA08 State Long-Term Care Ombudsman Program AGENCY: Administration on Aging, Administration for... Act, the State Long-Term Care Ombudsman program. This proposed rule replaces AoA's 1994 Notice of... highlighted the difficulty of determining State compliance in carrying out the Long-Term Care Ombudsman...

Stellar activity cycles from long-term data by robotic telescopes

NASA Astrophysics Data System (ADS)

Oláh, K.

2014-03-01

automated photometry+manual data from the literature, resulting in the detection of positive correlation between the rotational rates and cycle length(s) in the sense that faster rotating stars have shorter cycle(s). The long-term, B-V and U-B color index changes of active stars were thoroughly studied by Messina (2008). Direct connection between the magnetic behavior and the orbit of a system containing an active star is seldom observed; such examples are presented by Strassmeier et al. (2011) and Oláh et al. (2013). Based on the data from the DASCH (Digital Access to a Sky Century at Harvard) project, three active K-giants' long-term variability on the timescale of decades to 100 years have beed discovered by Tang et al. (2010). The ASAS database was used to study the cyclic behavior of field M-dwarf stars by Savanov (2012) who found no correlation between the rotation rates and cycle lengths of these objects, suggesting a different type of dynamo to those that drive the dynamo in the RS CVn systems and related active stars, e.g., in Oláh et al. (2009). Recently, Vida & Oláh (2013) determined cycles on the timescale of a year on fast rotating, late-type dwarf stars measured by the Kepler space telescope. However, despite the extremely high precision and time cadence, the Kepler data do not allow to study very long- term phenomena, such as the activity cycles of solar-like stars, due to the limited lifetime of the mission. One of the most important factors in studying stellar activity cycles is time, which cannot be overtaken by any means. It needs systematic, uninterrupted observations for dozens of years, preferably with the same instrument, to avoid systematic effects in the observed long-term variations. Another point is that most of the known magnetically active stars are quite bright objects needing a small telescope to be observed. The construction of automated photometric and spectroscopic telescopes is one of the major, and at the same time low

Influence of a counteradvertising media campaign on initiation of smoking: the Florida "truth" campaign.

PubMed Central

Sly, D F; Hopkins, R S; Trapido, E; Ray, S

2001-01-01

OBJECTIVES: The purpose of this study was to assess the short-term effects of television advertisements from the Florida "truth" campaign on rates of smoking initiation. METHODS: A follow-up survey of young people aged 12 to 17 years (n = 1820) interviewed during the first 6 months of the advertising campaign was conducted. Logistic regression analyses were used to estimate the independent effects of the campaign on smoking initiation while other factors were controlled for. RESULTS: Youths scoring at intermediate and high levels on a media effect index were less likely to initiate smoking than youths who could not confirm awareness of television advertisements. Adjusted odds ratios between the media index and measures of initiation were similar within categories of age, sex, susceptibility, and whether a parent smoked. CONCLUSIONS: Exposure to the "truth" media campaign lowered the risk of youth smoking initiation. However, the analysis did not demonstrate that all such media programs will be effective. PMID:11211631

Advancing an ethical framework for long-term care.

PubMed

Carter, Mary Whelan

2002-02-01

This article represents an effort to formulate an ethical framework for long-term care with the explicit purpose of providing a catalyst to promote further discourse and expand consideration of what an ethic of long-term care might entail. Grounding the discussion, an introduction to traditional ethical philosophy is presented, focusing mainly on the fundamentals of deontological and teleological ethical theories. Attention then shifts to a review of the more frequently cited principles found in the long-term care ethics literature, followed by a critique of the current reliance upon principlism to resolve ethical dilemmas in long-term care. In response to this criticism, an agent-driven ethical framework stressing dignity and respect for personhood, drawn from the philosophy of Immanuel Kant, is advanced.

Long-term memory, sleep, and the spacing effect.

PubMed

Bell, Matthew C; Kawadri, Nader; Simone, Patricia M; Wiseheart, Melody

2014-01-01

Many studies have shown that memory is enhanced when study sessions are spaced apart rather than massed. This spacing effect has been shown to have a lasting benefit to long-term memory when the study phase session follows the encoding session by 24 hours. Using a spacing paradigm we examined the impact of sleep and spacing gaps on long-term declarative memory for Swahili-English word pairs by including four spacing delay gaps (massed, 12 hours same-day, 12 hours overnight, and 24 hours). Results showed that a 12-hour spacing gap that includes sleep promotes long-term memory retention similar to the 24-hour gap. The findings support the importance of sleep to the long-term benefit of the spacing effect.

Mooring-based long-term observation of oceanographic condition in the Chukchi Ses and Canada Basin of the Arctic Ocean

NASA Astrophysics Data System (ADS)

Kikuchi, Takashi; Itoh, Motoyo; Nishino, Shigeto; Watanabe, Eiji

2015-04-01

Changes of the Arctic Ocean environment are well known as one of the most remarkable evidences of global warming, attracting social and public attentions as well as scientists'. However, to illustrate on-going changes and predict future condition of the Arctic marine environment, we still do not have enough knowledge of Arctic sea ice and marine environment. In particular, lack of observation data in winter, e.g., under sea ice, still remains a key issue for precise understanding of seasonal cycle on oceanographic condition in the Arctic Ocean. Mooring-based observation is one of the most useful methods to collect year-long data in the Arctic Ocean. We have been conducting long-term monitoring using mooring system in the Pacific sector of the Arctic Ocean. Volume, heat, and freshwater fluxes through Barrow Canyon where is a major conduit of Pacific-origin water-masses into the Canada Basin have been observed since 2000. We show from an analysis of the mooring results that volume flux through Barrow Canyon was about 60 % of Bering Strait volume flux. Averaged heat flux ranges from 0.9 to 3.07 TW, which could melt 88,000 to 300,000 km2 of 1m thick ice in the Canada Basin, which likely contributed to sea ice retreat in the Pacific sector of the Arctic Ocean. In winter, we found inter-annual variability in salinity related to coastal polynya activity in the Chukchi Sea. In collaboration with Distributed Biological Observatory (DBO) project, which is one of the tasks of Sustaining Arctic Observing Network (SAON), we also initiated year-long mooring observation in the Hope Valley of the southern Chukchi Sea since 2012. Interestingly, winter oceanographic conditions in the Hope Valley are greatly different between in 2012-2013 and in 2013-2014. We speculate that differences of sea ice freeze-up and coastal polynya activity in the southern Chukchi Sea cause significant difference of winter oceanographic condition. It suggests that recent sea ice reduction in the Pacific

Randomized controlled trial evaluating the temporal effects of high-intensity exercise on learning, short-term and long-term memory, and prospective memory.

PubMed

Frith, Emily; Sng, Eveleen; Loprinzi, Paul D

2017-11-01

The broader purpose of this study was to examine the temporal effects of high-intensity exercise on learning, short-term and long-term retrospective memory and prospective memory. Among a sample of 88 young adult participants, 22 were randomized into one of four different groups: exercise before learning, control group, exercise during learning, and exercise after learning. The retrospective assessments (learning, short-term and long-term memory) were assessed using the Rey Auditory Verbal Learning Test. Long-term memory including a 20-min and 24-hr follow-up assessment. Prospective memory was assessed using a time-based procedure by having participants contact (via phone) the researchers at a follow-up time period. The exercise stimulus included a 15-min bout of progressive maximal exertion treadmill exercise. High-intensity exercise prior to memory encoding (vs. exercise during memory encoding or consolidation) was effective in enhancing long-term memory (for both 20-min and 24-h follow-up assessments). We did not observe a differential temporal effect of high-intensity exercise on short-term memory (immediate post-memory encoding), learning or prospective memory. The timing of high-intensity exercise may play an important role in facilitating long-term memory. © 2017 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.