Community College Low-Income and Minority Student Completion Study: Descriptive Statistics from the 1992 High School Cohort

ERIC Educational Resources Information Center

Bailey, Thomas; Jenkins, Davis; Leinbach, Timothy

2005-01-01

This report summarizes statistics on access and attainment in higher education, focusing particularly on community college students, using data from the National Education Longitudinal Study of 1988 (NELS:88), which follows a nationally representative sample of individuals who were eighth graders in the spring of 1988. A sample of these…

Educational Engagement and Early Family Formation: Differences by Ethnicity and Generation

ERIC Educational Resources Information Center

Glick, Jennifer E.; Ruf, Stacey D.; White, Michael J.; Goldscheider, Frances K.

2006-01-01

This paper examines how school engagement influences the timing of family formation for youth. We pay particular attention to variation across four racial/ethnic groups and by generation status, variation that reflects the diversification of U.S. society through immigration. Using data from the National Education Longitudinal Study (NELS), we…

Beyond Family and Ethnic Culture: Understanding the Preconditions for the Potential Realization of Social Capital

ERIC Educational Resources Information Center

Oseguera, Leticia; Conchas, Gilberto Q.; Mosqueda, Eduardo

2011-01-01

This article extends our conceptual understanding of social capital and school achievement through a comparative race and ethnic approach. Using the National Educational Longitudinal Study (NELS) 1988-1990 panel, this article develops a more comprehensive understanding of school achievement by exploring circumstances, which the authors call…

The Role of Schools, Families, and Psychological Variables on Math Achievement of Black High School Students

ERIC Educational Resources Information Center

Strayhorn, Terrell L.

2010-01-01

Using data from the National Education Longitudinal Study (NELS;1988/2000), the author conducted hierarchical linear regression analyses, with a nested design, to estimate the influence of affective variables--parent involvement, teacher perceptions, and school environments--on Black students' math achievement in grade 10. Drawing on…

Predicting Teachers' Sense of Efficacy and Job Satisfaction Using School Climate and Participatory Decision Making.

ERIC Educational Resources Information Center

Taylor, Dianne L.; Tashakkori, Abbas

This study examined the relationship of teacher decisional participation and school climate to teachers' sense of efficacy and their job satisfaction. Data came from the National Education Longitudinal Study of 1988 (NELS-88) project, involving 1,035 schools with eighth grade students, and from the 1990 follow up of 1,296 schools. The final data…

Application to College: A Comparison of Asian American and White High School Students.

ERIC Educational Resources Information Center

Goyette, Kimberly

This paper explores an important component of the high college enrollment of Asian American students: application to college while in high school. Using data from the 1988-1992 waves of the National Educational Longitudinal Study (NELS), rates of application to college are compared for Asian Americans and Whites and various Asian American ethnic…

Do Gender and Ethnicity Affect Civic Engagement and Academic Progress? Working Paper 53

ERIC Educational Resources Information Center

Davila, Alberto; Mora, Marie T.

2007-01-01

Using panel data from the National Education Longitudinal Study of 1988 (NELS), the authors first analyze how civic engagement (measured in terms of community service and participation in student government) undertaken at the high school level varies across race/ethnicity and gender. The findings indicate that female high school students tend to…

What Are the Odds of that? A Primer on Understanding Logistic Regression

ERIC Educational Resources Information Center

Huang, Francis L.; Moon, Tonya R.

2013-01-01

The purpose of this Methodological Brief is to present a brief primer on logistic regression, a commonly used technique when modeling dichotomous outcomes. Using data from the National Education Longitudinal Study of 1988 (NELS:88), logistic regression techniques were used to investigate student-level variables in eighth grade (i.e., enrolled in a…

Academic Achievement Trajectories of Adolescents from Mexican and East Asian Immigrant Families in the United States

ERIC Educational Resources Information Center

Jeong, Yu-Jin; Acock, Alan C.

2014-01-01

Drawing on the National Educational Longitudinal Survey 1988 (NELS:88), this study identified (1) the growth pattern of academic achievement of adolescent children from Mexican and East Asian immigrant families; (2) investigated to what extent ethnicity and family capital influenced the trajectories in the academic achievement of children from…

The Advantages of Single-Sex Catholic Secondary Schooling: Selection Effects, School Effects, or "Much Ado About Nothing?"

ERIC Educational Resources Information Center

LePore, Paul C.; Warren, John Robert

Data from the National Education Longitudinal Study of 1988 (NELS:88) were used to investigate whether there are differences between single-sex and coeducational Catholic secondary school students in academic and social psychological outcomes, whether any differences especially favor young women in single-sex Catholic secondary schools, and…

Interpreting 12th-Graders' NAEP-Scaled Mathematics Performance Using High School Predictors and Postsecondary Outcomes from the National Education Longitudinal Study of 1988 (NELS:88). Statistical Analysis Report. NCES 2007-328

ERIC Educational Resources Information Center

Scott, Leslie A.; Ingels, Steven J.

2007-01-01

The search for an understandable reporting format has led the National Assessment Governing Board to explore the possibility of measuring and interpreting student performance on the 12th-grade National Assessment of Educational Progress (NAEP), the Nation's Report Card, in terms of readiness for college, the workplace, and the military. This…

Apri Gli Occi E Hai Le Cervello Nel Capo: Open Your Eyes and Keep Your Brains in Your Head: Narrative Stories from Italian Immigrant Women--Pasqualina, Susan, Matilde, & Filomena

ERIC Educational Resources Information Center

Pace, Josefa

2013-01-01

This three and a half year longitudinal study focused upon the social and cultural identities of four Italian women. In understanding and interpreting their identities, ethnographic data was analyzed through discourse and narrative analysis and presented in ways that recognized the importance of caring for their lives (Brandt, 2013), staying close…

Science Proficiency and Course Taking in High School: The Relationship of Science Course-Taking Patterns to Increases in Science Proficiency between 8th and 12th Grades.

ERIC Educational Resources Information Center

Madigan, Timothy

This analysis uses data on science achievement and transcript reports of science course taking patterns of students from the National Education Longitudinal Study of 1988 (NELS:88) to estimate the relationship between science course taking and the change in science proficiency levels between 8th and 12th grades. It also explores the extent to…

Educational Sequelae of High School Misbehavior

ERIC Educational Resources Information Center

Finn, Jeremy D.; Fish, Reva M.; Scott, Leslie A.

2008-01-01

Despite the fact that misbehavior in school is a pervasive problem to educators and despite its adverse consequences, few researchers have examined the range of misbehaviors by students, their antecedents, or their consequences. The authors used data from the National Education Longitudinal Survey of 1988 (NELS:88) conducted by the National Center…

The relationship between constructivist supervisory practices, school climate, and student proficiency in reading, mathematics, and science: Evidence from NELS:88

NASA Astrophysics Data System (ADS)

Molnar, John Alexander

In an effort to improve instruction and student learning, school reform efforts have become prevalent. School reformers have examined many aspects of the school experience, including learning theories such as behaviorism and constructivism, the changing roles of teachers and supervisors, and even the concept of the school itself. The theoretical framework for this study centered around constructivist learning theory. The study itself focused on the application of constructivist learning theory to the supervisory process. The study examined five areas of interest: (a) teachers' perceptions of constructivist supervisory behavior; (b) teachers' perceptions of efficacy and control in the classroom; (c) teachers' perceptions of school climate; (d) teachers' perceptions of job satisfaction, and (e) the influences of each of the aforementioned on student proficiency in mathematics, reading, and science. Data for the study was drawn from the first follow-up survey of the National Educational Longitudinal Study of 1988 (NELS: 88). NELS: 88 investigated a wide variety of factors that influence the educational process. The first follow-up focuses on environmental factors that affect teachers and students. Variables were selected from the NELS:88 data set that represented the areas to be examined. Factor analysis and correlational analysis were applied to ensure that the variables were measuring distinct constructs and to determine ways they could be grouped for analysis. Multiple linear regression analysis was applied to determine relationships among the individual and composite variables, controlling for student and teacher demographic factors. The results of the study suggest that varying relationships do exist between constructivist supervisory practices and the constructs measuring school climate and job satisfaction. The results also suggest that varying relationships exist between each of these factors and student proficiency in mathematics, reading, and science. Specifically, school climate, job satisfaction, and student proficiency were influenced by constructivist supervisory practices that included teachers' freedom to experiment with teaching and teachers' control over texts and materials.

Dear Nel: Opening the Circles of Care (Letters to Nel Noddings)

ERIC Educational Resources Information Center

Lake, Robert

2012-01-01

This collection is a moving tribute to Nel Noddings, a fascinating and influential scholar who has contributed greatly to numerous fields, including education, feminism, ethics, and the study of social justice and equity. "Dear Nel: Opening the Circles of Care" presents contributions from renowned teachers, educators, and activists, such as David…

When Money Might Matter: Using NELS88 to Examine the Weak Effects of School Funding

ERIC Educational Resources Information Center

Grubb, W. Norton

2006-01-01

In this article, the author continues to develop the perspective of the improved school finance, an effort to move beyond the conventional framing of funding and resource issues, presented in the article by Grubb, Huerta, and Goe in this issue. Here, the author presents the results of use of the National Educational Longitudinal Survey of the…

The Gender Wage Gap among Young Adults in the United States: The Importance of Money versus People

ERIC Educational Resources Information Center

Fortin, Nicole M.

2008-01-01

Using two single-cohort longitudinal surveys, the NLS72 and the NELS88, I investigate the impact of four noncognitive traits--self-esteem, external locus of control, the importance of money/work and the importance of people/family--on wages and on the gender wage gap among these young workers. I find that gender differences in these noncognitive…

Just the Facts, Ma'am: Postsecondary Education and Labor Market Outcomes in the U.S. IRP Discussion Paper No. 1411-13

ERIC Educational Resources Information Center

Holzer, Harry J.; Dunlop, Erin

2013-01-01

In this paper, we provide a comprehensive and up-to-date snapshot of the most important postsecondary education and labor market outcomes in the United States using two nationally representative sources of data: the Survey of Income and Program Participation (SIPP) and the National Educational Longitudinal Survey (NELS). We find that postsecondary…

Investigations on the Antifungal Effect of Nerol against Aspergillus flavus Causing Food Spoilage

PubMed Central

Tian, Jun; Zeng, Xiaobin; Zeng, Hong; Feng, Zhaozhong; Miao, Xiangmin; Peng, Xue

2013-01-01

The antifungal efficacy of nerol (NEL) has been proved against Aspergillus flavus by using in vitro and in vivo tests. The mycelial growth of A. flavus was completely inhibited at concentrations of 0.8 μL/mL and 0.1 μL/mL NEL in the air at contact and vapor conditions, respectively. The NEL also had an evident inhibitory effect on spore germination in A. flavus along with NEL concentration as well as time-dependent kinetic inhibition. The NEL presented noticeable inhibition on dry mycelium weight and synthesis of aflatoxin B1 (AFB1) by A. flavus, totally restraining AFB1 production at 0.6 μL/mL. In real food system, the efficacy of the NEL on resistance to decay development in cherry tomatoes was investigated in vivo by exposing inoculated and control fruit groups to NEL vapor at different concentration. NEL vapors at 0.1 μL/mL air concentration significantly reduced artificially contaminated A. flavus and a broad spectrum of fungal microbiota. Results obtained from presented study showed that the NEL had a great antifungal activity and could be considered as a benefit and safe tool to control food spoilage. PMID:24453813

Correlates of change in student reported parent involvement in schooling: a new look at the National Education Longitudinal Study of 1988.

PubMed

Stone, Susan

2006-10-01

Using a subsample (2174 students, 174 schools) from the National Education Longitudinal Study of 1988 (NELS), this study drew on Eccles and Harold's (1996) framework of parent involvement in schooling to estimate the relative influence of key child, family, and school characteristics on change in three types of student-reported parent involvement in schooling between eighth and tenth grades: home communication about school, monitoring, and direct interactions with schools. It also examines relationships between changes in involvement, change in grade point average (GPA), and dropout. Overall, measured school effects accounted for a small proportion of the variation in changes in home communication and direct parent interactions with schools. Sustained home communication related to higher grades and lower likelihood of dropout, although the size of effects was small. (c) 2007 APA, all rights reserved

The Consequences of Unrealized Occupational Goals in the Transition to Adulthood

PubMed Central

Hardie, Jessica Halliday

2014-01-01

Do unmet occupational goals have negative consequences for well-being? Several social-psychological theories posit that aspirations become standards against which individuals judge themselves, thereby decreasing well-being when unmet. Yet other evidence points to young adults’ goal flexibility and resilience, suggesting unmet aspirations may not affect well-being. This paper tests these alternatives using data from the National Longitudinal Study of Youth 1979 (N=9,016) and the National Educational Longitudinal Study of 1988 (N=10,547) to examine whether the degree of match between adolescent occupational aspirations (NLSY) and expectations (NELS) and later attainment affect job satisfaction and depression. This paper also examines gender differences in the cost to unmet goals. Findings reveal a cost to falling short of one’s occupational goals, manifested in more depressive symptoms for men in the older cohort, and lower job satisfaction for both men and women across two cohorts born approximately 14 years apart. PMID:25131285

Caring to Care: Applying Noddings' Philosophy to Medical Education.

PubMed

Balmer, Dorene F; Hirsh, David A; Monie, Daphne; Weil, Henry; Richards, Boyd F

2016-12-01

The authors argue that Nel Noddings' philosophy, "an ethic of caring," may illuminate how students learn to be caring physicians from their experience of being in a caring, reciprocal relationship with teaching faculty. In her philosophy, Noddings acknowledges two important contextual continuities: duration and space, which the authors speculate exist within longitudinal integrated clerkships. In this Perspective, the authors highlight core features of Noddings' philosophy and explore its applicability to medical education. They apply Noddings' philosophy to a subset of data from a previously published longitudinal case study to explore its "goodness of fit" with the experience of eight students in the 2012 cohort of the Columbia-Bassett longitudinal integrated clerkship. In line with Noddings' philosophy, the authors' supplementary analysis suggests that students (1) recognized caring when they talked about "being known" by teaching faculty who "cared for" and "trusted" them; (2) responded to caring by demonstrating enthusiasm, action, and responsibility toward patients; and (3) acknowledged that duration and space facilitated caring relations with teaching faculty. The authors discuss how Noddings' philosophy provides a useful conceptual framework to apply to medical education design and to future research on caring-oriented clinical training, such as longitudinal integrated clerkships.

NASA Electronic Library System (NELS) database schema, version 1.2

NASA Technical Reports Server (NTRS)

Melebeck, Clovis J.

1991-01-01

The database tables used by NELS version 1.2 are discussed. To provide the current functional capability offered by NELS, nineteen tables were created with ORACLE. Each table lists the ORACLE table name and provides a brief description of the tables intended use or function. The following sections cover four basic categories of tables: NELS object classes, NELS collections, NELS objects, and NELS supplemental tables. Also included in each section is a definition and/or relationship of each field to other fields or tables. The primary key(s) for each table is indicated with a single asterisk (*), while foreign keys are indicated with double asterisks (**). The primary key(s) indicate the key(s) which uniquely identifies a record for that table. The foreign key(s) is used to identify additional information in other table(s) for that record. The two appendices are the command which is used to construct the ORACLE tables for NELS. Appendix A contains the commands which create the tables which are defined in the following sections. Appendix B contains the commands which build the indices for these tables.

Good things come in threes: single-parent multigenerational family structure and adolescent adjustment.

PubMed

Deleire, Thomas; Kalil, Ariel

2002-05-01

Using data from the National Educational Longitudinal Study (NELS), we found that teenagers who live in nonmarried families are less likely to graduate from high school or to attend college, more likely to smoke or drink, and more likely to initiate sexual activity. Not all nonmarried families are alike, however. In particular, teenagers living with their single mothers and with at least one grandparent in multigenerational households have developmental outcomes that are at least as good and often better than the outcomes of teenagers in married families. These findings obtain when a wide array of economic resources, parenting behavior, and home and school characteristics are controlled for.

An ecological perspective of science and math academic achievement among African American students

NASA Astrophysics Data System (ADS)

Stewart, Endya Bentley

Using data from the National Education Longitudinal Study of 1988 (NELS:88), path analytic procedures were performed to test an ecological model of the effects of family, individual and school characteristics on the academic African American students. A distinctive study is the inclusion of school computer use in the model. The study results show that several of the variables directly or indirectly affected 12th grade academic achievement. Furthermore, most of the individual influence variables were directly related to 12 th grade achievement. Two surprising findings from this study were the insignificant effects of family income and school computer use on 12 th grade achievement. Overall, the findings support the notion that family, individual, and school characteristics are important predictors of academic success among African American students.

NELS 2.0 - A general system for enterprise wide information management

NASA Technical Reports Server (NTRS)

Smith, Stephanie L.

1993-01-01

NELS, the NASA Electronic Library System, is an information management tool for creating distributed repositories of documents, drawings, and code for use and reuse by the aerospace community. The NELS retrieval engine can load metadata and source files of full text objects, perform natural language queries to retrieve ranked objects, and create links to connect user interfaces. For flexibility, the NELS architecture has layered interfaces between the application program and the stored library information. The session manager provides the interface functions for development of NELS applications. The data manager is an interface between session manager and the structured data system. The center of the structured data system is the Wide Area Information Server. This system architecture provides access to information across heterogeneous platforms in a distributed environment. There are presently three user interfaces that connect to the NELS engine; an X-Windows interface, and ASCII interface and the Spatial Data Management System. This paper describes the design and operation of NELS as an information management tool and repository.

NASA Electronic Library System (NELS) optimization

NASA Technical Reports Server (NTRS)

Pribyl, William L.

1993-01-01

This is a compilation of NELS (NASA Electronic Library System) Optimization progress/problem, interim, and final reports for all phases. The NELS database was examined, particularly in the memory, disk contention, and CPU, to discover bottlenecks. Methods to increase the speed of NELS code were investigated. The tasks included restructuring the existing code to interact with others more effectively. An error reporting code to help detect and remove bugs in the NELS was added. Report writing tools were recommended to integrate with the ASV3 system. The Oracle database management system and tools were to be installed on a Sun workstation, intended for demonstration purposes.

Extended Experience with Neuroendoscopic Lavage for Posthemorrhagic Hydrocephalus in Neonates.

PubMed

d'Arcangues, Charlotte; Schulz, Matthias; Bührer, Christoph; Thome, Ulrich; Krause, Matthias; Thomale, Ulrich-Wilhelm

2018-05-03

Previous studies have described neuroendoscopic lavage (NEL) as a procedure for the treatment of posthemorrhagic hydrocephalus in newborn infants. This report describes complications and results in an extended case series from 2 separate hospitals. Patient records were screened for NEL procedures performed on infants with posthemorrhagic hydrocephalus between September 2010 and May 2016 (minimum follow-up period of 12 months). Efficacy of blood removal-as assessed with cerebral ultrasound, complications, eventual shunt placement rate, and subsequent shunt revisions-were recorded. Fifty-six patients (35 male) underwent NEL at a postmenstrual median age of 31 weeks and 2 days (range, 26 weeks and 1 day to 52 weeks and 3 days) and a median weight of 1523 g (range, 734-4360 g). Median follow-up was 34 months (range, 12-80). Three patients died, and 31 patients required permanent ventriculoperitoneal shunting. There was no significant correlation between the need for ventriculoperitoneal shunting and gestational age (P = 0.05), birth weight (P = 0.07), age (P = 0.17), or weight (P = 0.59) after NEL. The median number of surgical interventions per patient was 2 (range, 1-7 interventions). Revision-free shunt survival was 63.6% at 12 and 56.2% at 24 months. NEL avoided shunt placement in 43% of newborn infants with posthemorrhagic hydrocephalus. In the shunted cohort, NEL may have also decreased the frequency of subsequent shunt revisions. The influence of NEL on neurodevelopment and safety remains to be investigated further in a multicenter setup. Copyright © 2018 Elsevier Inc. All rights reserved.

PLGA-PEG Nanoparticles Coated with Anti-CD45RO and Loaded with HDAC Plus Protease Inhibitors Activate Latent HIV and Inhibit Viral Spread

NASA Astrophysics Data System (ADS)

Tang, Xiaolong; Liang, Yong; Liu, Xinkuang; Zhou, Shuping; Liu, Liang; Zhang, Fujina; Xie, Chunmei; Cai, Shuyu; Wei, Jia; Zhu, Yongqiang; Hou, Wei

2015-10-01

Activating HIV-1 proviruses in latent reservoirs combined with inhibiting viral spread might be an effective anti-HIV therapeutic strategy. Active specific delivery of therapeutic drugs into cells harboring latent HIV, without the use of viral vectors, is a critical challenge to this objective. In this study, nanoparticles of poly(lactic-co-glycolic acid)-polyethylene glycol diblock copolymers conjugated with anti-CD45RO antibody and loaded with the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) and/or protease inhibitor nelfinavir (Nel) were tested for activity against latent virus in vitro. Nanoparticles loaded with SAHA, Nel, and SAHA + Nel were characterized in terms of size, surface morphology, zeta potential, entrapment efficiency, drug release, and toxicity to ACH-2 cells. We show that SAHA- and SAHA + Nel-loaded nanoparticles can target latently infected CD4+ T-cells and stimulate virus production. Moreover, nanoparticles loaded with SAHA + NEL were capable of both activating latent virus and inhibiting viral spread. Taken together, these data demonstrate the potential of this novel reagent for targeting and eliminating latent HIV reservoirs.

A two-domain protein triggers heat shock pathway and necrosis pathway both in model plant and nematode.

PubMed

Ruan, Lifang; Wang, Huihui; Cai, Ge; Peng, Donghai; Zhou, Hua; Zheng, Jinshui; Zhu, Lei; Wang, Xixi; Yu, Haoquan; Li, Seng; Geng, Ce; Sun, Ming

2015-11-01

The entomopathogen Bacillus thuringiensis is equipped with multiple virulent factors. The genome sequence of B. thuringiensis YBT1520 revealed the presence of a two-domain protein named Nel which is composed of a necrosis-inducing phytophthora protein 1-like domain found in phytopathogens and a ricin B-like lectin domain. The merging of two distantly related domains is relatively rare. Nel induced necrosis and pathogen-triggered immunity (PTI) on model plants. The Nel also exhibited inhibition activity to nematode. Microscopic observation showed that the toxicity of Nel to nematodes targets the intestine. Quantitative proteomics revealed that Nel stimulated the host defence. The Nel thus possesses dual roles, as both toxin and elicitor. Remarkably, the Nel protein triggered a similar response, induction of the heat shock pathway and the necrosis pathway, in both model plants and nematodes. The unusual ability of Nel to function across kingdom suggests a highly conserved mechanism in eukaryotes that predates the divergence of plants and animal. It is also speculated that the two-domain protein is the result of horizontal gene transfer (HGT) between phytopathogens and entomopathogens. Our results provide an example that HGT occurs between members of different species or even genera with lower frequency are particularly important for evolution of new bacterial pathogen lineages with new virulence. Bacillus thuringiensis occupies the same ecological niches, plant and soil, as phytopathogens, providing the opportunity for gene exchange. © 2015 Society for Applied Microbiology and John Wiley & Sons Ltd.

Eclipsing damped Ly α systems in the Sloan Digital Sky Survey Data Release 12

NASA Astrophysics Data System (ADS)

Fathivavsari, H.; Petitjean, P.; Jamialahmadi, N.; Khosroshahi, H. G.; Rahmani, H.; Finley, H.; Noterdaeme, P.; Pâris, I.; Srianand, R.

2018-07-01

We present the results of our automatic search for proximate damped Ly α absorption (PDLA) systems in the quasar spectra from the Sloan Digital Sky Survey Data Release 12. We constrain our search to those PDLAs lying within 1500 km s-1 from the quasar to make sure that the broad DLA absorption trough masks most of the strong Ly α emission from the broad-line region (BLR) of the quasar. When the Ly α emission from the BLR is blocked by these so-called eclipsing DLAs, narrow Ly α emission from the host galaxy could be revealed as a narrow emission line (NEL) in the DLA trough. We define a statistical sample of 399 eclipsing DLAs with log N(H I) ≥ 21.10. We divide our statistical sample into three subsamples based on the strength of the NEL detected in the DLA trough. By studying the stacked spectra of these subsamples, we found that absorptions from high ionization species are stronger in DLAs with stronger NEL in their absorption core. Moreover, absorption from the excited states of species like SIII are also stronger in DLAs with stronger NEL. We also found no correlation between the luminosity of the Ly α NEL and the quasar luminosity. These observations are consistent with a scenario in which the DLAs with stronger NEL are denser and physically closer to the quasar. We propose that these eclipsing DLAs could be the product of the interaction between infalling and outflowing gas. High-resolution spectroscopic observation would be needed to shed some light on the nature of these eclipsing DLAs.

[Anesthesia in single and bilateral sequential lung transplantation. Lung Transplantation Group].

PubMed

Della Rocca, G; Coccia, C; Pugliese, F; Pompei, L; Ruberto, F; Costa, M G; Venuta, F; Rendina, E A; De Giacomo, T; Pietropaoli, P; Gasparetto, A

2000-04-01

Anesthesia for lung transplantation: intraoperative complications and long term results. 52 patients were scheduled for 16 single lung transplantations (SLT) (9 fibrosis and 7 emphysema) and 36 bilateral sequential lung transplantations (DLT) (4 bronchiectasis, 6 emphysema, 3 fibrosis, 22 cystic fibrosis and 1 pulmonary hypertension). Anesthesia was induced with propofol or midazolam, and fentanyl or alfentanil. As muscle relaxant vecuronium bromide was used. Anesthesia was maintained with isoflurane, fentanyl in boluses or sufentanil continuous infusion in O2 100%. Prostaglandin E1 (20-300 ng/kg/min), inhaled nitric oxide (10-40 ppm), dobutamine (5-15 mcg/kg/min), norepinephrine (0.05-3 mcg/kg/min) and ephedrine (5-10 mg per bolus) were used for hemodynamic management. In 2 patients inhaled areosolized prostacyclin were administered. Mean pulmonary arterial pressure (mPA) and pulmonary vascular resistance (PVRI) increased after pulmonary artery clamping during first lung (mPA: 3347 nel DLT, 3643 nel SLT; PVRI; 375488 nel DLT, 377420 nel SLT) and second lung implantation (mPA: 3746; PVRI: 263553) and decreased after reperfusion of the first (mPA: 4737 nel DLT, 4329 nel SLT; PVRI: 488263 nel DLT, 420233 nel SLT) and the second lung (mPA: 4629; PVRI: 553260). Only in 9 cases (7 DLT and 2 SLT) C-P bypass was used. With a strong drug support with pulmonary vasodilators, positive inotropic and systemic vasoconstrictor drugs, in most patients we transplanted C-P bypass can be avoided. Intraoperative deaths were not observed. Two years actuarial survival is 65% for DLT and 60% for SLT.

UNCERTAINTY IN EARLY OCCUPATIONAL ASPIRATIONS: ROLE EXPLORATION OR AIMLESSNESS?

PubMed Central

Staff, Jeremy; Harris, Angel; Sabates, Ricardo; Briddell, Laine

2014-01-01

Many youth in the United States lack clear occupational aspirations. This uncertainty in achievement ambitions may benefit socioeconomic attainment if it signifies “role exploration,” characterized by career development, continued education, and enduring partnerships. By contrast, uncertainty may diminish attainment if it instead leads to “aimlessness,” involving prolonged education without the acquisition of a degree, residential dependence, and frequent job changes. We use nationally representative data from the National Education Longitudinal Study (NELS) to examine how uncertainty in occupational aspirations in adolescence (age 16) affects wage attainments in young adulthood (age 26). Results suggest that youth with uncertain career ambitions earn significantly lower hourly wages in young adulthood than youth with professional and non-professional aspirations, supporting the view that uncertainty heightens the risk of labor-market problems. PMID:25540465

Weeded Out? Gendered Responses to Failing Calculus.

PubMed

Sanabria, Tanya; Penner, Andrew

2017-06-01

Although women graduate from college at higher rates than men, they remain underrepresented in science, technology, engineering, and mathematics (STEM) fields. This study examines whether women react to failing a STEM weed-out course by switching to a non-STEM major and graduating with a bachelor's degree in a non-STEM field. While competitive courses designed to weed out potential STEM majors are often invoked in discussions around why students exit the STEM pipeline, relatively little is known about how women and men react to failing these courses. We use detailed individual-level data from the National Educational Longitudinal Study (NELS) Postsecondary Transcript Study (PETS): 1988-2000 to show that women who failed an introductory calculus course are substantially less likely to earn a bachelor's degree in STEM. In doing so, we provide evidence that weed-out course failure might help us to better understand why women are less likely to earn degrees.

The gender gap reloaded: are school characteristics linked to labor market performance?

PubMed

Konstantopoulos, Spyros; Constant, Amelie

2008-06-01

This study examines the wage gender gap of young adults in the 1970s, 1980s, and 2000 in the US. Using quantile regression we estimate the gender gap across the entire wage distribution. We also study the importance of high school characteristics in predicting future labor market performance. We conduct analyses for three major racial/ethnic groups in the US: Whites, Blacks, and Hispanics, employing data from two rich longitudinal studies: NLS and NELS. Our results indicate that while some school characteristics are positive and significant predictors of future wages for Whites, they are less so for the two minority groups. We find significant wage gender disparities favoring men across all three surveys in the 1970s, 1980s, and 2000. The wage gender gap is more pronounced in higher paid jobs (90th quantile) for all groups, indicating the presence of a persistent and alarming "glass ceiling."

Weeded Out? Gendered Responses to Failing Calculus

PubMed Central

Sanabria, Tanya; Penner, Andrew

2018-01-01

Although women graduate from college at higher rates than men, they remain underrepresented in science, technology, engineering, and mathematics (STEM) fields. This study examines whether women react to failing a STEM weed-out course by switching to a non-STEM major and graduating with a bachelor’s degree in a non-STEM field. While competitive courses designed to weed out potential STEM majors are often invoked in discussions around why students exit the STEM pipeline, relatively little is known about how women and men react to failing these courses. We use detailed individual-level data from the National Educational Longitudinal Study (NELS) Postsecondary Transcript Study (PETS): 1988–2000 to show that women who failed an introductory calculus course are substantially less likely to earn a bachelor’s degree in STEM. In doing so, we provide evidence that weed-out course failure might help us to better understand why women are less likely to earn degrees. PMID:29616148

Eclipsing damped Lyα systems in the Sloan Digital Sky Survey Data Release 12★

NASA Astrophysics Data System (ADS)

Fathivavsari, H.; Petitjean, P.; Jamialahmadi, N.; Khosroshahi, H. G.; Rahmani, H.; Finley, H.; Noterdaeme, P.; Pâris, I.; Srianand, R.

2018-04-01

We present the results of our automatic search for proximate damped Lyα absorption (PDLA) systems in the quasar spectra from the Sloan Digital Sky Survey Data Release 12. We constrain our search to those PDLAs lying within 1500 km s-1 from the quasar to make sure that the broad DLA absorption trough masks most of the strong Lyα emission from the broad line region (BLR) of the quasar. When the Lyα emission from the BLR is blocked by these so-called eclipsing DLAs, narrow Lyα emission from the host galaxy could be revealed as a narrow emission line (NEL) in the DLA trough. We define a statistical sample of 399 eclipsing DLAs with log N(H I) ≥ 21.10. We divide our statistical sample into three subsamples based on the strength of the NEL detected in the DLA trough. By studying the stacked spectra of these subsamples, we found that absorption from high ionization species are stronger in DLAs with stronger NEL in their absorption core. Moreover, absorption from the excited states of species like Si II are also stronger in DLAs with stronger NEL. We also found no correlation between the luminosity of the Lyα NEL and the quasar luminosity. These observations are consistent with a scenario in which the DLAs with stronger NEL are denser and physically closer to the quasar. We propose that these eclipsing DLAs could be the product of the interaction between infalling and outflowing gas. High resolution spectroscopic observation would be needed to shed some light on the nature of these eclipsing DLAs.

An in vitro evaluation of some unconventional ruminant feeds in terms of the organic matter digestibility, energy and microbial biomass.

PubMed

Al-Masri, M R

2003-04-01

In vitro organic matter apparent digestibility (IVOMAD), true digestibility (IVOMTD), metabolizable energy (ME), net energy lactation (NEL), microbial nitrogen (MN) and synthesis of microbial biomass (MBM) were estimated to predict the nutritive values of some agricultural by-products, drought-tolerant range plants and browses. The relationships between in vitro gas production (GP), and true or apparent digestibility. MN and MBM were studied utilizing an in vitro incubation technique. The values of IVOMAD, IVOMTD, ME, NEL, GP, MBM and MN varied with the studied experimental materials. The true fermentation of the outside part of Atriplex leucoclada produced a higher volume of gas than the middle or the inside parts, and this was associated with an increase in the values of IVOMAD, IVOMTD, ME and NEL. However, screening off the wood from olive cake to obtain olive cake pulp increased the IVOMAD, IVOMTD, ME, NEL and the volume of gas production from the true fermented material. One ml of gas was generated from the true degradation of 5 mg of wheat straw, Moringa oleifera, Alhagi camelorum, Eucaliptus camaldulensis and A. leucoclada, from 11 mg of Prosopsis stephaniana and olive cake pulp, and from 20 mg of olive cake or olive cake wood. The amount of MN or MBM produced from 100 mg of truly fermented organic matter depended on the kind of the fermented material and amounted to 0.7-2.9 mg or 8-34 mg, respectively. Crude fibre was negatively correlated to IVOMAD, IVOMTD, ME and NEL. Gas production was positively correlated to IVOMAD and IVOMTD but negatively correlated to MBM and MN.

Composite Overview and Composite Aerocover Overview

NASA Technical Reports Server (NTRS)

Caraccio, Anne; Tate, LaNetra; Dokos, Adam; Taylor, Brian; Brown, Chad

2014-01-01

Materials Science Division within the Engineering Directorate tasked by the Ares Launch Vehicle Division (LX-V) and the Fluids Testing and Technology Development Branch (NE-F6) to design, fabricate and test an aerodynamic composite shield for potential Heavy Lift Launch Vehicle infusion and a composite strut that will serve as a pathfinder in evaluating calorimeter data for the CRYOSTAT (cryogenic on orbit storage and transfer) Project. ATP project is to carry the design and development of the aerodynamic composite cover or "bracket" from cradle to grave including materials research, purchasing, design, fabrication, testing, analysis and presentation of the final product. Effort consisted of support from the Materials Testing & Corrosion Control Branch (NE-L2) for mechanical testing, the Prototype Development Branch (NE-L3) for CAD drawing, design/analysis, and fabrication, Materials & Processes Engineering Branch (NE-L4) for project management and materials selection; the Applied Physics Branch (NE-LS) for NDE/NDI support; and the Chemical Analysis Branch (NE-L6) for developmental systems evaluation. Funded by the Ares Launch Vehicle Division and the Fluids Testing and Technology Development Branch will provide ODC

The Role of School in the Upward Mobility of Disadvantaged Immigrants’ Children

PubMed Central

HAO, LINGXIN; PONG, SUET-LING

2014-01-01

How can we explain exceptional advancement by disadvantaged immigrants’ children? Extending segmented assimilation theory, this article traces the structural and relational attributes of high schools attended by young adults who reached their late twenties in 2000. Hypotheses are derived from theories in sociology of education and tested with four waves of data from the National Educational Longitudinal Study (NELS). The authors offer three major findings. First, an overwhelming majority of disadvantaged students attend public schools; some relational attributes are typical in public schools attended by disadvantaged students. Second, children’s upward mobility is shaped by the structural and relational attributes of their high schools. Most school effects are the same for disadvantaged and advantaged youngsters, and student-educator bonds and curriculum structure have even stronger positive effects for the disadvantaged. Finally, mobility patterns differ widely among Chinese, Mexicans, and whites. Mexicans are less likely to be exposed to favorable school attributes. PMID:25418989

A new genus and species of micro bee fly from the Earliest Eocene French amber (Diptera: Mythicomyiidae: Psiloderoidinae).

PubMed

Myskowiak, Justine; Garrouste, Romain; Nel, Andre

2016-05-26

Mythicomyiidae, or micro bee flies, are tiny flies (0.5-5.0 mm) that are found throughout most parts of the world except the highest altitudes and latitudes (Greathead & Evenhuis 2001). Including all extinct and extant taxa, the Mythicomyiidae currently comprise more than 380 valid taxonomic species distributed among 30 genera. The subfamily Psiloderoidinae is especially well represented among the fossil Mythicomyiidae by seven Cretaceous or Cenozoic genera. We here describe a new genus and a new species of this subfamily based on fossils from the Earliest Eocene of Oise (France). A Psiloderoidinae, Proplatypygus matilei Nel & DePloëg, 2004, is already described in this amber. Another mythicomyiid, Eurodoliopteryx inexpectatus Nel, 2006, is the most frequent bombylioid in this amber (Nel & DePloëg, 2004; Nel, 2006).

Studies on effective atomic numbers for photon energy absorption and electron density of some narcotic drugs in the energy range 1 keV-20 MeV

NASA Astrophysics Data System (ADS)

Gounhalli, Shivraj G.; Shantappa, Anil; Hanagodimath, S. M.

2013-04-01

Effective atomic numbers for photon energy absorption ZPEA,eff, photon interaction ZPI,eff and for electron density Nel, have been calculated by a direct method in the photon-energy region from 1 keV to 20 MeV for narcotic drugs, such as Heroin (H), Cocaine (CO), Caffeine (CA), Tetrahydrocannabinol (THC), Cannabinol (CBD), Tetrahydrocannabivarin (THCV). The ZPEA,eff, ZPI,eff and Nel values have been found to change with energy and composition of the narcotic drugs. The energy dependence ZPEA,eff, ZPI,eff and Nel is shown graphically. The maximum difference between the values of ZPEA,eff, and ZPI,eff occurs at 30 keV and the significant difference of 2 to 33% for the energy region 5-100 keV for all drugs. The reason for these differences is discussed.

Gamma shielding properties of Tamoxifen drug

NASA Astrophysics Data System (ADS)

Kanberoglu, Gulsah Saydan; Oto, Berna; Gulebaglan, Sinem Erden

2017-02-01

Tamoxifen (MW=371 g/mol) is an endocrine therapeutic drug widely prescribed as chemopreventive in women to prevent and to treat all stages of breast cancer. It is also being studied for other types of cancer. In this study, we have calculated some gamma shielding parameters such as mass attenuation coefficient (μρ), effective atomic number (Zeff) and electron density (Nel) for Tamoxifen drug. The values of μρ were calculated using WinXCom computer program and then the values of Zeff and Nel were derived using μρ values in the wide energy range (1 keV - 100 GeV).

Predictors of Student Persistence in the STEM Pipeline: Activities Outside the Classroom, Parent Aspirations, and Student Self-Beliefs using NELS:88 Data

NASA Astrophysics Data System (ADS)

Miller, Joelle A.

Focusing on Science, Technology, Engineering and Mathematics (STEM) literacy is a national priority for the United States. As competition increases internationally for scientific and technological innovations, the United States is concentrating on building its STEM capacity (Stephens, 2011). Despite the numerous STEM reform efforts there continues to be a decline in STEM graduates and STEM competencies (McNally, 2012; Langdon, Mckittrick, Beede, Doms, & Khan, 2011; Herschback, 2011). With attention focused on increasing STEM college majors and occupations among the student population, the current research investigation centered on the role of parent aspirations, student self-beliefs, and activities outside the classroom to determine the outcome of middle and high school students choosing a STEM college major. Research suggested that students formulate their degree attainment during their middle and high school years, and even earlier (Roach, 2006; Maltese & Tai, 2011); therefore, it was logical to investigate STEM persistence during middle and high school years. The study analyzed NELS:88, a longitudinal national public data set created by the National Center for Educational Statistics that used 12,144 participants. The students' self-reported data spanned over a 12-year period. Students completed five surveys in the NELS:88 data collection (NCES, 2011). Binary and multivariate logistical regressions determined if activities outside the classroom, parent aspirations, and student self-beliefs influenced STEM college majors. Conclusions of the study found significant relationships between the variables and STEM persistence. Individuals who participated in STEM activities after school were more likely to major in STEM (p<.001,Exp(B)=1.106). There was a significant positive relationship between parent aspirations and increased odds of choosing a STEM major (p<.0001, Exp(B)=1.041). There was a significant relationship between student self-beliefs and choosing a STEM major as students with higher self-beliefs had a decreased odds of choosing a non-STEM major (p<.05, Exp(B)=.988). When all three variables were considered together, self-beliefs were no longer significant (p<.166) but parent aspirations, (p<.0001, Exp(B)=1.034) and activities outside of the classroom (p<.0001, Exp(B)=1.097), both significantly predicted STEM participation. The results of the research inform policy makers in regard to funding decisions and the development of programs, especially ones that occur outside of the school day. The analysis may guide decisions for school administrators on how to influence student retention within the STEM pipeline. The findings add to existing research and provide a better understanding of predictors affecting student persistence in STEM.

Liver Hypertrophy After Percutaneous Portal Vein Embolization: Comparison of N-Butyl-2-Cyanocrylate Versus Sodium Acrylate-Vinyl Alcohol Copolymer Particles in a Swine Model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tsoumakidou, Georgia, E-mail: gtsoumakidou@yahoo.com; Theocharis, Stamatis, E-mail: theocharis@ath.forthnet.gr; Ptohis, Nikolaos, E-mail: nikptohis@yahoo.gr

2011-10-15

Purpose: Percutaneous portal vein embolization (PPVE) induces hypertrophy of the future liver remnant before hepatic resection. The ideal embolic material has not yet been determined. We compared N-butyl-2-cyanocrylate (NBCA) with sodium acrylate-vinyl alcohol copolymer particles using a swine model. Materials and Methods: Twelve pigs underwent PPVE. Six pigs (group A) were embolized with NBCA, and 6 pigs (group B) were embolized with sodium acrylate-vinyl alcohol copolymer particles. Computed tomographic volumetry of the embolized lobe (EL) and the nonembolized lobe (NEL), along with liver function tests, was performed before and at 14 and 28 days after embolization. Tissue samples from bothmore » lobes were taken 14 and 28 days after PPVE. Results: NEL-volume and NEL-ratio increases were significantly higher in group A at 14 and 28 days after PPVE (78 and 52% and 91 and 66%, respectively) than in group B (32 and 12% and 28 and 10%, respectively) (p < 0.05). Percent change of the EL-volume was significantly higher for group A at 28 days after PPVE. No statistically significant difference was found between the groups regarding hepatocyte proliferation on the NEL and apoptosis on the EL at both time intervals. Conclusion: PPVE using NBCA is more efficient and causes more NEL hypertrophy than microspheres.« less

Pre-EDIT: protocol for a randomised feasibility trial of elastance-directed intrapleural catheter or talc pleurodesis (EDIT) in malignant pleural effusion

PubMed Central

Martin, Geoffrey A; Tsim, Selina; Kidd, Andrew C; Foster, John E; McLoone, Philip; Chalmers, Anthony

2018-01-01

Introduction Non-expansile lung (NEL) is a common cause of talc pleurodesis (TP) failure in malignant pleural effusion (MPE), but is often occult prior to drainage. Reliable detection of NEL would allow patients to be allocated between intrapleural catheter (IPC) and TP. High pleural elastance (PEL) has been associated with NEL in observational studies. Pre-EDIT is a randomised feasibility trial of elastance-directed IPC or TP (EDIT) management using a novel, purpose-built digital pleural manometer (Rocket Medical, UK). Methods and analysis Consecutive patients with MPE without prior evidence of NEL or preference for IPC will be randomised 1:1 between EDIT management and standard care (an attempt at TP). The primary objective is to determine whether sufficient numbers of patients (defined as 30 within 12 months (or 15 over 6 months)) can be recruited and randomised to justify a subsequent phase III trial testing the efficacy of EDIT management. Secondary objectives include safety, technical feasibility and validation of study design elements, including the definition of PEL using 4D pleural MRI before and after fluid aspiration. EDIT involves PEL assessment during a large volume pleural fluid aspiration, followed by an attempt at TP or placement of an IPC within 24 hours. Patients will be allocated to IPC if the rolling average PEL sustained over at least 250 mL fluid aspirated (PEL250) is ≥ 14.5 cm H2O/L. Ethics and dissemination Pre-EDIT was approved by the West of Scotland Regional Ethics Committee on 8 March 2017 (Ref: 17/WS/0042). Results will be presented at scientific meetings and published in peer-reviewed journals. Trial registration number NCT03319186; Pre-results. PMID:29862030

An "Ideal" Home for Care: Nel Noddings, Thomas Hill Green, and an Ontological Support for a Phenomenology of Care

ERIC Educational Resources Information Center

Decoste, Jordan; Boyd, Dwight

2009-01-01

This paper is grounded in a deep appreciation of Nel Noddings' "ethics of care" as an important contribution to moral philosophy and moral education. We seek to offer some philosophical reflections that have the potential to strengthen this important alternative to mainstream ethics and to how moral education might be conceived and practiced…

Description of a bovine model for studying digestive and metabolic effects of a positive energy balance not biased by lactation or gravidity.

PubMed

Dänicke, Sven; Meyer, Ulrich; Winkler, Janine; Schulz, Kirsten; Ulrich, Sebastian; Frahm, Jana; Kersten, Susanne; Rehage, Jürgen; Breves, Gerhard; Häussler, Susanne; Sauerwein, Helga; Locher, Lena

2014-12-01

Physiological consequences of adaptation to and continued feeding of a high-energetic diet were studied in eight non-pregnant, non-lactating dairy Holstein cows over a period of 16 weeks. The first six weeks served as an adaptation period from the low energetic straw-based diet (3.8 MJ NEL/kg DM) to the high-energetic ration (7.5 MJ NEL/kg DM). Intake of dry matter (DM) increased with dietary energy concentration from 9 to 20 kg/d up to week 9 to 12 and decreased thereafter. The initial live weight (LW) of 550 ± 60 kg was increased linearly and corresponded to an average daily LW gain of 2.3 ± 0.3 kg. Energy balance increased approximately nine-fold to a maximum of 114 MJ NEL/d in week 10. Ruminal fermentation pattern was completely changed from an acetate dominating profile to a propionate based one, which was paralleled by a marked increase in the rumen fluid endotoxin concentration. Unlike blood glucose concentration, which increased continuously, that of cholesterol and triglycerides started to increase after an initial stagnation. In conclusion, both ruminal adaptation to a high-energetic diet and the continued feeding of such a diet induced digestive and metabolic adaptations in non-pregnant, non-lactating cows characterised by a progressing positive energy balance.

Re-examining the role of interscholastic sport participation in education.

PubMed

Yin, Zenong; Moore, Justin B

2004-06-01

The purpose of the present study was to examine the relationships of interscholastic sports participation with locus of control, self-concept, cognitive test scores, and school dropout in adolescents via a secondary analysis of National Educational Longitudinal Study 1988 (NELS:88). Subjects were 1,883 students who completed all measurements in 8th grade (1988), at Follow-up 1 (10th, 1990), and Follow-up 2 (12th, 1992). Scales utilized to measure locus of control, self-concept, and cognitive ability were developed by the National Center for Educational Statistics. Dropout was assessed through school records and contact with participants. At baseline and Follow-up 1, students self-reporting sport participation displayed higher self-concept and locus of control; however, these differences were no longer observed at Follow-up 2. Drop-out rate for boys at Follow-up 2 was significantly lower for students reporting interscholastic sport participation at baseline or at Follow-up 1. Similarly, drop-out rate for girls at Follow-up 2 was significantly lower for students reporting interscholastic sport participation at baseline or at Follow-up 1. These findings support the presumed positive role of sport participation for adolescents in American schools.

Expecting the Unexpected: a Comparative Study of African-American Women's Experiences in Science during the High School Years

NASA Astrophysics Data System (ADS)

Hanson, Sandra L.; Johnson, Elizabeth Palmer

Data from the National Educational Longitudinal Study (NELS) for the years 1988 to 1992 are used to explore the science experiences of young African-American women during the high school years. The comparison groups we use in trying to understand these experiences involve White women (for a race contrast) and African-American men (for a gender contrast). Within the context of a critical feminist perspective, it is argued that gender is constructed in a different way in White and African-American communities. Instead of expecting a disadvantage for young African-American women because of their gender and minority statuses, it is suggested that unique gender ideologies and work-family arrangements in the African-American community give these young women the resources and agency that allow them to compete with their White female counterparts and their African-American male counterparts in the science domain. Results from our analyses of the NELS data confirm these expectations. We find that on a majority of science measures, African-American women do as well as - and sometimes better than - White women and African-American men. For example, there are no differences between African-American women and men on attitudes toward science. And when compared with White women, African-American women tend to have more positive attitudes. When disadvantages appear for these young African-American women, they are more likely to be race effects then gender effects. The minimal gender effects in the science experiences of young African-Americans is in contrast to the more frequent male advantage in the White sample. A careful examination of family and individual resources shows that African-American families compensate for disadvantages on some resources (e.g., family socioeconomic status) by providing young women with an excess of other resources (e.g., unique gender ideologies, work expectations, and maternal expectations and involvement). And, unlike White parents, they sometimes provide more of these resources to their daughters than to their sons. Results do not support the popular notion that because minorities and women do less well in science African-American women will be especially disadvantaged in science. Implications of these findings are discussed.

Misura della sezione d'urto totale e Dello scattering elastico all'energia Nel centro di massa di $$\\sqrt{s}=1.8$$ TeV (in Italian)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Paoletti, Riccardo

La produzione di eventi elastici è stata misurata al Collider Tevatron del Fermi National Accelerator Laboratory (Batavia. 11.~ U .S.A.) alla energia nel centro di massa. di √s = 1800 GeV, nell'intervallo 0.06 < I t I< 0.24. Sono forniti dettagli sull'esperimento CDF che ha compiuto la misura e sui criteri di selezione degli eventi.

Synthetic progestins induce growth and metastasis of BT-474 human breast cancer xenografts in nude mice.

PubMed

Liang, Yayun; Benakanakere, Indira; Besch-Williford, Cynthia; Hyder, Ryyan S; Ellersieck, Mark R; Hyder, Salman M

2010-01-01

Previous studies have shown that sequential exposure to estrogen and progesterone or medroxyprogesterone acetate (MPA) stimulates vascularization and promotes the progression of BT-474 and T47-D human breast cancer cell xenografts in nude mice (Liang et al, Cancer Res 2007, 67:9929). In this follow-up study, the effects of progesterone, MPA, norgestrel (N-EL), and norethindrone (N-ONE) on BT-474 xenograft tumors were compared in the context of several different hormonal environments. N-EL and N-ONE were included in the study because synthetic progestins vary considerably in their biological effects and the effects of these two progestins on the growth of human tumor xenografts are not known. Estradiol-supplemented intact and ovariectomized immunodeficient mice were implanted with BT-474 cells. Progestin pellets were implanted simultaneously with estradiol pellets either 2 days before tumor cell injection (ie, combined) or 5 days after tumor cell injections (ie, sequentially). Progestins stimulated the growth of BT-474 xenograft tumors independent of exposure timing and protocol, MPA stimulated the growth of BT-474 xenograft tumors in ovariectomized mice, and progestins stimulated vascular endothelial growth factor elaboration and increased tumor vascularity. Progestins also increased lymph node metastasis of BT-474 cells. Therefore, progestins, including N-EL and N-ONE, induce the progression of breast cancer xenografts in nude mice and promote tumor metastasis. These observations suggest that women who ingest progestins for hormone therapy or oral contraception could be more at risk for developing breast cancer because of proliferation of existing latent tumor cells. Such risks should be considered in the clinical setting.

NASA Electronic Library System (NELS): The system impact of security

NASA Technical Reports Server (NTRS)

Mcgregor, Terry L.

1993-01-01

This paper discusses security issues as they relate to the NASA Electronic Library System which is currently in use as the repository system for AdaNET System Version 3 (ASV3) being operated by MountainNET, Inc. NELS was originally designed to provide for public, development, and secure collections and objects. The secure feature for collections and objects was deferred in the initial system for implementation at a later date. The NELS system is now 9 months old and many lessons have been learned about the use and maintenance of library systems. MountainNET has 9 months of experience in operating the system and gathering feedback from the ASV3 user community. The user community has expressed an interest in seeing security features implemented in the current system. The time has come to take another look at the whole issue of security for the NELS system. Two requirements involving security have been put forth by MountainNET for the ASV3 system. The first is to incorporate at the collection level a security scheme to allow restricted access to collections. This should be invisible to end users and be controlled by librarians. The second is to allow inclusion of applications which can be executed only by a controlled group of users; for example, an application which can be executed by librarians only. The requirements provide a broad framework in which to work. These requirements raise more questions than answers. To explore the impact of these requirements a top down approach will be used.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ge Junqiang; Hu Chen; Wang Jianmin

Recently, much attention has been paid to double-peaked narrow emission-line (NEL) galaxies, some of which are suggested to be related to merging galaxies. We make a systematic search to build the largest sample of these sources from Data Release 7 of the Sloan Digital Sky Survey (SDSS). With reasonable criteria for fluxes, FWHMs of the emission lines, and separations of the peaks, we select 3030 double-peaked NEL galaxies. In light of the existence of broad Balmer lines and the locations of the two components of double-peaked NELs distinguished by the Kauffmann et al. criteria in the Baldwin-Phillips-Terlevich diagram, we findmore » that there are 81 Type I active galactic nuclei (AGNs), 837 double Type II AGNs (2-Type II), 708 galaxies with double star-forming components (2-SF), 400 with mixed star-forming and Type II AGN components (Type II + SF), and 1004 unknown-type objects. As a by-product, a sample of galaxies (12,582) with asymmetric or top-flat profiles of emission lines is established. After visually inspecting the SDSS images of the two samples, we find 54 galaxies with dual cores. The present samples can be used to study the dynamics of merging galaxies, the triggering mechanism of black hole activity, the hierarchical growth of galaxies, and the dynamics of narrow line regions driven by outflows and a rotating disk.« less

Synthetic progestins induce growth and metastasis of BT-474 human breast cancer xenografts in nude mice

PubMed Central

Liang, Yayun; Benakanakere, Indira; Besch-Williford, Cynthia; Hyder, Ryyan S; Ellersieck, Mark R.; Hyder, Salman M

2010-01-01

Objective Previous studies showed that sequential exposure to estrogen and progesterone or medroxyprogesterone acetate (MPA) stimulates vascularization and promotes the progression of BT-474 and T47-D human breast cancer cell xenografts in nude mice (Liang et al, Cancer Res 2007, 67:9929). In this follow-up study, the effects of progesterone, MPA, norgestrel (N-EL) and norethindrone (N-ONE) on BT-474 xenograft tumors were compared in the context of several different hormonal environments. N-EL and N-ONE were included in the study since synthetic progestins vary considerably in their biological effects and the effects of these two progestins on the growth of human tumor xenografts are not known. Methods Estradiol-supplemented intact and ovariectomized Immunodeficient mice were implanted with BT-474 cells. Progestin pellets were implanted either simultaneously with estradiol pellets 2-days prior to tumor cell injection (i.e. combined), or 5-days following tumor cell injections (i.e. sequentially). Results Progestins stimulated the growth of BT-474 xenograft tumors independent of exposure timing and protocol, MPA stimulated the growth of BT-474 xenograft tumors in ovariectomized mice and progestins stimulated VEGF elaboration and increased tumor vascularity. Progestins also increased lymph node metastasis of BT-474 cells. Therefore, progestins, including N-EL and N-ONE, induce the progression of breast cancer xenografts in nude mice and promote tumor metastasis. Conclusions These observations suggests that women who ingest progestins for HT or oral contraception could be more at risk for developing breast cancer as a result of proliferation of existing latent tumor cells. Such risks should be considered in the clinical setting. PMID:20461021

USDA Nutrition Evidence Library: methodology used to identify topics and develop systematic review questions for the birth-to-24-mo population.

PubMed

Obbagy, Julie E; Blum-Kemelor, Donna M; Essery, Eve V; Lyon, Joan M G; Spahn, Joanne M

2014-03-01

The USDA's Nutrition Evidence Library (NEL) specializes in conducting food- and nutrition-related systematic reviews that are used to inform federal government decision making. To ensure the utility of NEL systematic reviews, the most relevant topics must be addressed, questions must be clearly focused and appropriate in scope, and review frameworks must reflect the state of the science. Identifying the optimal topics and questions requires input from a variety of stakeholders, including scientists with technical expertise, as well as government policy and program leaders. The objective of this article is to describe the rationale and NEL methodology for identifying topics and developing systematic review questions implemented as part of the "Evaluating the evidence base to support the inclusion of infants and children from birth to 24 months of age in the Dietary Guidelines for Americans--the B-24 Project." This is the first phase of a larger project designed to develop dietary guidance for the birth to 24-mo population in the United States.

[La diagnosi del disturbo da uso di alcol dal punto di vista psicologico].

PubMed

Coriale, Giovanna; Fiorentino, Daniela; Porrari, Raffaella; Battagliese, Gemma; Capriglione, Ida; Cereatti, Federica; Iannuzzi, Silvia; Mauri, Benilde; Galli, Domenica; Fiore, Marco; Attilia, Maria Luisa; Ceccanti, Mauro

2018-01-01

RIASSUNTO. Il disturbo da uso di alcol (DUA) è uno dei disturbi psichiatrici più comuni nella popolazione generale. Il DUA è caratterizzato da un pattern di bere eccessivo, che si mantiene nonostante gli effetti negativi che l'alcol ha sul funzionamento lavorativo, sulla salute, sulle problematiche legali, sull'educazione e sulla vita sociale. Attualmente, il modello bio-psico-sociale è quello che spiega meglio il DUA. Infatti, molte ricerche hanno fornito evidenze su come il DUA sia una patologia multidimensionale. Variabili biologiche, psicologiche e socio-culturali entrano in gioco nell'eziologia, nella natura, nel mantenimento e nel cambiamento nel tempo del disturbo. La fase diagnostica è un momento importante del processo di cura, perché il successo del trattamento dipende in larga misura dall'esattezza e dall'adeguatezza della diagnosi. La diagnosi clinica si basa su una valutazione globale del funzionamento del paziente e utilizza il colloquio e gli strumenti psicometrici come mezzo di raccolta di informazioni. Questo articolo fornirà una panoramica delle dimensioni psicologiche più importanti da valutare e sui migliori strumenti psicometrici da usare per una diagnosi adeguata.

[Ecological study on the mortality of residents in Manfredonia (Apulia Region, Southern Italy) from 1970 to 2013].

PubMed

Gianicolo, Emilio Antonio Luca; Mangia, Cristina; Cervino, Marco; Bruni, Antonella; De Marchi, Bruna; Biggeri, Annibale; Porcu, Rosa; Vigotti, Maria Angela

2016-01-01

OBIETTIVI: valutare lo stato di salute della popolazione residente nel comune di Manfredonia dal 1970 al 2013. DISEGNO: analisi descrittiva dell'andamento temporale della mortalità generale, per gruppi di cause, dal 1970 al 2013. SETTING E PARTECIPANTI: i dati di mortalità e le popolazioni residenti sono di fonte Istat. Sono state esaminate 55 cause di decesso. Le analisi sono disaggregate per sesso e periodo. PRINCIPALI MISURE DI OUTCOME: sono stati elaborati i rapporti standardizzati di mortalità (SMR%), con i rispettivi intervalli di confidenza al 90% (IC90%), e i tassi di mortalità standardizzati col metodo diretto (TSD ). RISULTATI: lo stato di salute misurato dal tasso di mortalità per tutte le cause migliora nel tempo: i TSD passano da 92 x10.000 negli anni 1970-1974 a 52 x10.000 nel biennio 2012-2013 negli uomini, da 70 x10.000 a 39 x10.000 nelle donne. Tuttavia, rispetto alla media regionale Manfredonia perde progressivamente il suo vantaggio, passando da -20% a -10% negli uomini, e da -20% a +1,5% nelle donne. Questo andamento è molto evidente per il complesso delle cause cardiovascolari, mentre i tumori maligni sono in generale nella media regionale. Nell'ultimo periodo disponibile per causa di decesso (2006-2011), la mortalità per infarto miocardico è stata più alta della media regionale (uomini: +35%; donne: +54%). I rapporti standardizzati di mortalità (SMR) mostrano tra gli uomini valori in crescita, in particolar modo rispetto al riferimento provinciale, con un eccesso a cominciare dal periodo 2006-2011 (22 decessi/anno e 19 attesi; SMR%: 117,2; IC90% 101,1-135,2; riferimento: provincia di Foggia). Anche tra le donne gli SMR% superano i riferimenti provinciali negli ultimi periodi esaminati (nel 2012-2013: 7 decessi/ anno e 4,2 attesi; SMR%: 116,4; IC90% 97,0-260,7; riferimento: provincia di Foggia). CONCLUSIONI: la mortalità a Manfredonia è diminuita in misura minore rispetto a quella osservata nei riferimenti provinciali e regionali. Il vantaggio che si osservava negli anni Sessanta si è, infatti, ridotto nel tempo, fino ad annullarsi negli ultimi anni. Dal 1970, Manfredonia ha progressivamente perso il vantaggio che aveva. Dagli anni Duemila, la mortalità per infarto del miocardio è in eccesso sulla media regionale e provinciale. Da casi documentati in letteratura si osserva che le popolazioni che sperimentano catastrofi di origine naturale o antropica possono fronteggiare un aumento di patologie cardiovascolari. La mortalità per tumore polmonare mostra un eccesso sulla media regionale, in particolare provinciale, a cominciare dal 2000, coerentemente con i tempi di latenza legati all'esposizione ad arsenico negli anni Settanta.

The Supervision Dance: Learning to Lead and Follow a Student Teacher

ERIC Educational Resources Information Center

Trout, Muffet

2008-01-01

This article chronicles the journey of a student teaching supervisor as she worked with one of her student teachers. Early in their relationship, the supervisor's assessment of the student teacher's dispositions for teaching triggered concern. In this self-study, the supervisor was guided by Nel Noddings' (2003) phenomenological description of…

Nationwide Participation in 4-H during the 1980s: Information from the Office of Education NELS:88 Study.

ERIC Educational Resources Information Center

Steele, Sara M.; And Others

A study examined national participation in 4-H Club activities during the 1980s. The study population was a carefully drawn sample of 24,500 eighth graders from more than 1,000 public and private schools throughout the country as well as their parents and teachers. The study established that, as of 1988, about one of every six eighth-grade…

Isolation and characterization of Candida albicans morphological mutants derepressed for the formation of filamentous hypha-type structures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gil, C.; Pomes, R.; Nombela, C.

1990-05-01

Several Candida albicans morphological mutants were obtained by a procedure based on a combined treatment with nitrous acid plus UV irradiation and a double-enrichment step to increase the proportion of mutants growing as long filamentous structures. Altered cell morphogenesis in these mutants correlated with an altered colonial phenotype. Two of these mutants, C. albicans NEL102 and NEL103, were selected and characterized. Mutant blastoconidia initiated budding but eventually gave rise to filamentous hypha-type formations. These filaments were long and septate, and they branched very regularly at positions near septa. Calcofluor white (which is known to bind chitin-rich areas) stained septa, branchingmore » zones, and filament tips very intensely, as observed under the fluorescence microscope. Wild-type hybrids were obtained by fusing protoplasts of strain NEL102 with B14, another morphological mutant previously described as being permanently pseudomycelial, indicating that genetic determinants responsible for the two altered phenotypes are different. The mutants characterized in this work seemed to sequentially express the morphogenic characteristics of C. albicans, from blastoconidia to hyphae, in the absence of any inducer. Further characterization of these strains could be relevant to gain understanding of the genetic control of dimorphism in this species.« less

Human-induced greening of the northern extratropical land surface

NASA Astrophysics Data System (ADS)

Mao, J.; Ribes, A.; Yan, B.; Shi, X.; Thornton, P. E.; Seferian, R.; Ciais, P.; Myneni, R. B.; Douville, H.; Piao, S.; Zhu, Z.; Dickinson, R. E.; Dai, Y. J.; Ricciuto, D. M.; Jin, M.; Hoffman, F. M.; Wang, B.; Huang, M.; Lian, X.

2016-12-01

Significant land greening in the northern extratropical latitudes (NEL) has been documented through satellite observations during the past three decades. This enhanced vegetation growth has broad implications for surface energy, water and carbon budgets, and ecosystem services across multiple scales. Discernible human impacts on the Earth's climate system have been revealed by using statistical frameworks of detection-attribution. These impacts, however, were not previously identified on the NEL greening signal, owing to the lack of long-term observational records, possible bias of satellite data, different algorithms used to calculate vegetation greenness, and the lack of suitable simulations from coupled Earth system models (ESMs). Here we have overcome these challenges to attribute recent changes in NEL vegetation activity. We used two 30-year-long remote-sensing-based leaf area index (LAI) data sets, simulations from 19 coupled ESMs with interactive vegetation, and a formal detection and attribution algorithm. Our findings reveal that the observed greening record is consistent with an assumption of anthropogenic forcings, where greenhouse gases play a dominant role, but is not consistent with simulations that include only natural forcings and internal climate variability. These results provide the first clear evidence of a discernible human fingerprint on physiological vegetation changes other than phenology and range shifts.

Human-induced greening of the northern extratropical land surface

NASA Astrophysics Data System (ADS)

Mao, Jiafu; Ribes, Aurélien; Yan, Binyan; Shi, Xiaoying; Thornton, Peter E.; Séférian, Roland; Ciais, Philippe; Myneni, Ranga B.; Douville, Hervé; Piao, Shilong; Zhu, Zaichun; Dickinson, Robert E.; Dai, Yongjiu; Ricciuto, Daniel M.; Jin, Mingzhou; Hoffman, Forrest M.; Wang, Bin; Huang, Mengtian; Lian, Xu

2016-10-01

Significant land greening in the northern extratropical latitudes (NEL) has been documented through satellite observations during the past three decades. This enhanced vegetation growth has broad implications for surface energy, water and carbon budgets, and ecosystem services across multiple scales. Discernible human impacts on the Earth's climate system have been revealed by using statistical frameworks of detection-attribution. These impacts, however, were not previously identified on the NEL greening signal, owing to the lack of long-term observational records, possible bias of satellite data, different algorithms used to calculate vegetation greenness, and the lack of suitable simulations from coupled Earth system models (ESMs). Here we have overcome these challenges to attribute recent changes in NEL vegetation activity. We used two 30-year-long remote-sensing-based leaf area index (LAI) data sets, simulations from 19 coupled ESMs with interactive vegetation, and a formal detection and attribution algorithm. Our findings reveal that the observed greening record is consistent with an assumption of anthropogenic forcings, where greenhouse gases play a dominant role, but is not consistent with simulations that include only natural forcings and internal climate variability. These results provide the first clear evidence of a discernible human fingerprint on physiological vegetation changes other than phenology and range shifts.

Human-induced greening of the northern extratropical land surface

DOE PAGES

Mao, Jiafu; Ribes, Aurélien; Yan, Binyan; ...

2016-06-27

Significant land greening in the northern extratropical latitudes (NEL) has been documented from satellite observations during the past three decades. This enhanced vegetation growth has broad implications for surface energy, water and carbon budgets, and ecosystem services across multiple scales. Discernible human impacts on the Earth’s climate system have been revealed by using statistical frameworks of detection–attribution. These impacts, however, were not previously identified on the NEL greening signal, owing to the lack of long-term observational records, possible bias of satellite data, different algorithms used to calculate vegetation greenness, and the lack of suitable simulations from coupled Earth system modelsmore » (ESMs). Here we have overcome these challenges to attribute recent changes in NEL vegetation activity. We have used two 30-year-long remote-sensing-based leaf area index (LAI) data sets, simulations from 19 coupled ESMs with interactive vegetation, and a formal detection and attribution algorithm. Our findings reveal that the observed greening record is consistent with an assumption of anthropogenic forcings, where greenhouse gases play a dominant role, but is not consistent with simulations that include only natural forcings and internal climate variability. These results provide the first clear evidence of a discernible human fingerprint on physiological vegetation changes other than phenology and range shifts.« less

Intensive Behavioral Intervention for School-Aged Children with Autism: Una Breccia nel Muro (UBM)--A Comprehensive Behavioral Model

ERIC Educational Resources Information Center

Fava, Leonardo; Vicari, Stefano; Valeri, Giovanni; D'Elia, Lidia; Arima, Serena; Strauss, Kristin

2012-01-01

Although, reviews and outcome research supports empirical evidence for Early Intensive Behavior Intervention in pre-scholars, intensive behavioral service provision for school-aged children with autism spectrum disorders (ASD) are less subject to research studies. In order to provide effective behavioral interventions for school-aged children it…

Ralstonia solanacearum novel E3 ubiquitin ligase (NEL) effectors RipAW and RipAR suppress pattern-triggered immunity in plants.

PubMed

Nakano, Masahito; Oda, Kenji; Mukaihara, Takafumi

2017-07-01

Ralstonia solanacearum is the causal agent of bacterial wilt in solanaceous crops. This pathogen injects more than 70 effector proteins into host plant cells via the Hrp type III secretion system to cause a successful infection. However, the function of these effectors in plant cells, especially in the suppression of plant immunity, remains largely unknown. In this study, we characterized two Ralstonia solanacearum effectors, RipAW and RipAR, which share homology with the IpaH family of effectors from animal and plant pathogenic bacteria, that have a novel E3 ubiquitin ligase (NEL) domain. Recombinant RipAW and RipAR show E3 ubiquitin ligase activity in vitro. RipAW and RipAR localized to the cytoplasm of plant cells and significantly suppressed pattern-triggered immunity (PTI) responses such as the production of reactive oxygen species and the expression of defence-related genes when expressed in leaves of Nicotiana benthamiana. Mutation in the conserved cysteine residue in the NEL domain of RipAW completely abolished the E3 ubiquitin ligase activity in vitro and the ability to suppress PTI responses in plant leaves. These results indicate that RipAW suppresses plant PTI responses through the E3 ubiquitin ligase activity. Unlike other members of the IpaH family of effectors, RipAW and RipAR had no leucine-rich repeat motifs in their amino acid sequences. A conserved C-terminal region of RipAW is indispensable for PTI suppression. Transgenic Arabidopsis plants expressing RipAW and RipAR showed increased disease susceptibility, suggesting that RipAW and RipAR contribute to bacterial virulence in plants.

Failure Analysis of Nonvolatile Residue (NVR) Analyzer Model SP-1000

NASA Technical Reports Server (NTRS)

Potter, Joseph C.

2011-01-01

National Aeronautics and Space Administration (NASA) subcontractor Wiltech contacted the NASA Electrical Lab (NE-L) and requested a failure analysis of a Solvent Purity Meter; model SP-IOOO produced by the VerTis Instrument Company. The meter, used to measure the contaminate in a solvent to determine the relative contamination on spacecraft flight hardware and ground servicing equipment, had been inoperable and in storage for an unknown amount of time. NE-L was asked to troubleshoot the unit and make a determination on what may be required to make the unit operational. Through the use of general troubleshooting processes and the review of a unit in service at the time of analysis, the unit was found to be repairable but would need the replacement of multiple components.

The Shipbuilding Technology Transfer Program, Program Summary Report

DTIC Science & Technology

1981-08-31

Davis Highway, Suite 1204, Arlington VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law, no person shall be...NAME OF RESPONSIBLE PERSON a. REPORT unclassified b. ABSTRACT unclassified c. THIS PAGE unclassified Standard Form 298 (Rev. 8-98) Prescribed...Information for this study was derived from source documentation sup- plied by IHI, information obtained directly from IHI consulting person - nel

Effects of partly replacing dietary starch with fiber and fat on milk production and energy partitioning.

PubMed

Boerman, J P; Potts, S B; VandeHaar, M J; Lock, A L

2015-10-01

The effects of partly replacing dietary starch with fiber and fat to provide a diet with similar net energy for lactation (NEL) density on yields of milk and milk components and on energy partitioning were evaluated in a crossover design experiment. Holstein cows (n = 32; 109 ± 22 d in milk, mean ± standard deviation) were randomly assigned to treatment sequence. Treatments were a high-starch diet containing 33% corn grain (mixture of dry ground and high-moisture corn; HS) or a high-fiber, high-fat diet containing 2.5% palmitic acid-enriched fatty acid (FA) supplement (HFF). Diets contained corn silage, alfalfa silage, and wheat straw as forage sources; HS contained 32% starch, 3.2% FA, and 25% neutral detergent fiber, whereas HFF contained 16% starch, 5.4% FA, and 33% neutral detergent fiber. Compared with HS, the HFF treatment reduced milk yield, milk protein concentration, and milk protein yield, but increased milk fat concentration, milk fat yield, milk energy output, and milk to feed ratio (energy-corrected milk/dry matter intake). The HFF treatment reduced the yield of de novo synthesized (< 16-carbon) milk FA and increased the yield of 16-carbon milk FA. Yield of preformed (> 16-carbon) milk FA was not different. The HFF treatment increased plasma concentrations of triglycerides and nonesterified fatty acids, but decreased plasma concentration of insulin. Compared with HS, the HFF treatment reduced body weight gain, change in body condition score, and fat thickness over the rump and rib. Calculated body energy gain, as a fraction of NEL use, was less for HFF than HS, whereas milk energy as a fraction of NEL use was increased for HFF. We concluded that the 2 treatments resulted in similar apparent NEL densities and intakes, but the HS treatment partitioned more energy toward body gain whereas the HFF treatment partitioned more energy toward milk. A high-fiber, high-fat diet might diminish the incidence of over conditioning in mid-lactation cows while maintaining high milk production. Copyright © 2015 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Economic impact of nutritional grouping in dairy herds.

PubMed

Kalantari, A S; Armentano, L E; Shaver, R D; Cabrera, V E

2016-02-01

This article evaluates the estimated economic impact of nutritional grouping in commercial dairy herds using a stochastic Monte Carlo simulation model. The model was initialized by separate data sets obtained from 5 commercial dairy herds. These herds were selected to explore the effect of herd size, structure, and characteristics on the economics and efficiency of nutrient usage according to nutritional grouping strategies. Simulated status of each cow was updated daily together with the nutrient requirements of net energy for lactation (NEL) and metabolizable protein (MP). The amount of energy consumed directly affected body weight (BW) and body condition score (BCS) changes. Moreover, to control the range of observed BCS in the model, constraints on lower (2.0) and upper (4.5) bounds of BCS were set. Each month, the clustering method was used to homogeneously regroup the cows according to their nutrient concentration requirements. The average NEL concentration of the group and a level of MP (average MP, average MP+0.5SD, or average MP+1SD) were considered to formulate the group diet. The calculated income over feed costs gain (IOFC, $/cow per yr) of having >1 nutritional group among the herds ranged from $33 to $58, with an average of $39 for 2 groups and $46 for 3 groups, when group was fed at average NEL concentration and average MP+1SD concentration. The improved IOFC was explained by increased milk sales and lower feed costs. Higher milk sales were a result of fewer cows having a milk loss associated with low BCS in multi-group scenarios. Lower feed costs in multi-group scenarios were mainly due to less rumen-undegradable protein consumption. The percentage of total NEL consumed captured in milk for >1 nutritional group was slightly lower than that for 1 nutritional group due to better distribution of energy throughout the lactation and higher energy retained in body tissue, which resulted in better herd BCS distribution. The percentage of fed N captured in milk increased with >1 group and was the most important factor for improved economic efficiency of grouping strategies. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Carotid baroreflex control of leg vasculature in exercising and non-exercising skeletal muscle in humans

PubMed Central

Melvin Keller, David; Fadel, Paul J; Ogoh, Shigehiko; Matthew Brothers, Robert; Hawkins, Megan; Olivencia-Yurvati, Al; Raven, Peter B

2004-01-01

Carotid baroreflex (CBR) function was examined in five men and three women (25 ± 1 years) using the variable-pressure neck collar technique at rest and during dynamic, one-legged knee extension exercise at 7 W and 25 W. The CBR exhibited control of leg vascular conductance (LVC) at rest and during exercise in both an exercising leg (EL) and a non-exercising leg (NEL) across a wide range of pressures from +40 Torr neck pressure (NP) to −80 Torr neck suction (NS). Specifically, increases in LVC (% change) in response to NS were no different across −20 to −80 Torr in either EL or NEL compared to rest, P > 0.05. However, CBR-mediated decreases in percentage LVC in response to NP were attenuated in EL at both 7 W (16 ± 1%) and 25 W (12 ± 1%) compared to rest (40 ± 3%; P < 0.05) as well as compared to responses in the NEL (36 ± 6% at 7 W and 36 ± 7% at 25 W; P < 0.05). This decrease in vascular responsiveness in EL was associated with a reduction in the gain of the percentage muscle sympathetic nerve activity (%MSNA)–%LVC relationship compared to rest (P < 0.05). Collectively, these data indicate that, despite a clear attenuation of the vascular response to MSNA in the exercising leg, CBR-mediated changes in mean arterial pressure were no different between rest and exercise. PMID:15388778

L'influenza dell'ambiente linguistico nel processo di acquisizione di un lessico bilingue (Influence of the Linguistic Environment on the Process of Acquiring a Bilingual Vocabulary).

ERIC Educational Resources Information Center

Cavosi, Ricciarda; Taeschner, Traute

1987-01-01

Addresses two questions: (1) When do children who are bilingual from birth become aware that they speak two languages? and (2) What are the factors that lead to this awareness? The subjects in the study described here were Italian/German bilingual children living in the Italian region of Alto Adige. (CFM)

Novel Wnt Regulator NEL-Like Molecule-1 Antagonizes Adipogenesis and Augments Osteogenesis Induced by Bone Morphogenetic Protein 2

PubMed Central

Shen, Jia; James, Aaron W.; Zhang, Xinli; Pang, Shen; Zara, Janette N.; Asatrian, Greg; Chiang, Michael; Lee, Min; Khadarian, Kevork; Nguyen, Alan; Lee, Kevin S.; Siu, Ronald K.; Tetradis, Sotirios; Ting, Kang; Soo, Chia

2017-01-01

The differentiation factor NEL-like molecule-1 (NELL-1) has been reported as osteoinductive in multiple in vivo preclinical models. Bone morphogenetic protein (BMP)-2 is used clinically for skeletal repair, but in vivo administration can induce abnormal, adipose-filled, poor-quality bone. We demonstrate that NELL-1 combined with BMP2 significantly optimizes osteogenesis in a rodent femoral segmental defect model by minimizing the formation of BMP2-induced adipose-filled cystlike bone. In vitro studies using the mouse bone marrow stromal cell line M2-10B4 and human primary bone marrow stromal cells have confirmed that NELL-1 enhances BMP2-induced osteogenesis and inhibits BMP2-induced adipogenesis. Importantly, the ability of NELL-1 to direct BMP2-treated cells toward osteogenesis and away from adipogenesis requires intact canonical Wnt signaling. Overall, these studies establish the feasibility of combining NELL-1 with BMP2 to improve clinical bone regeneration and provide mechanistic insight into canonical Wnt pathway activity during NELL-1 and BMP2 osteogenesis. The novel abilities of NELL-1 to stimulate Wnt signaling and to repress adipogenesis may highlight new treatment approaches for bone loss in osteoporosis. PMID:26772960

[Population health surveillance of the general population living near Turin (Northern Italy) incinerator (SPoTT): methodology of the study].

PubMed

Bena, Antonella; Chiusolo, Monica; Orengia, Manuela; Cadum, Ennio; Farina, Elena; Musmeci, Loredana; Procopio, Enrico; Salamina, Giuseppe

2016-01-01

Si intende qui descrivere il sistema di sorveglianza sugli effetti sulla salute (SpoTT) dell'inquinamento ambientale nelle aree circostanti l'inceneritore di Torino. SPoTT ha 3 linee di attività: 1. monitoraggio epidemiologico degli effetti a breve termine attraverso analisi temporali e misura della correlazione tra livelli giornalieri di emissioni dell'impianto e andamento degli eventi individuati dagli archivi dei dimessi (SDO), di pronto soccorso e di mortalità; sono coinvolti coloro che nel 2013-2018 risiedevano nell'area di ricaduta delle emissioni; 2. sorveglianza epidemiologica degli effetti a lungo termine, stimando tassi standardizzati di mortalità e morbosità; a ogni soggetto è attribuito il valore stimato di esposizione cumulato nel tempo caratteristico della residenza anagrafica; le informazioni sulla salute sono reperite dagli archivi SDO, di mortalità e dai certificati di assistenza al parto; sono studiati due decenni pre-post l'avvio dell'impianto: 2003-2012 e 2013-2022; 3. monitoraggio biologico con misurazione pre-post di metalli, PCDD/F, PCB, OH-IPA; sono coinvolti 196 residenti esposti e 196 di controllo di 35-69 anni, campionati a caso dalle anagrafi comunali; sono effettuate misure di funzionalità endocrina e respiratoria, pressione arteriosa, rischio cardiovascolare; l'esposizione cumulativa sarà stimata per ciascuna persona campionata integrando l'indirizzo di residenza, il tempo di permanenza in ciascun indirizzo e i dati ricavati dai modelli di ricaduta; sarà costituita una biobanca per future indagini di laboratorio; sono coinvolti anche 20 allevatori e i lavoratori dell'impianto. Una quarta linea di attività, non descritta in questo articolo, riguarda il monitoraggio della salute dei lavoratori addetti all'impianto. SPoTT è il primo studio in Italia su inceneritori e salute che adotta un disegno di studio longitudinale di adeguata potenza sia per i residenti sia per i lavoratori. I primi risultati sono attesi nel corso del 2016.

Prediction of physical and chemical body compositions of purebred and crossbred Nellore cattle using the composition of a rib section.

PubMed

Marcondes, M I; Tedeschi, L O; Valadares Filho, S C; Chizzotti, M L

2012-04-01

The goal of this research was to develop empirical equations to predict chemical and physical compositions of the carcass and the body using the composition of the 9th- to 11th-rib section (rib(9-11)) and other measurements. A database (n = 246) from 6 studies was developed and comprised 37 bulls (BU), 115 steers (STR), and 94 heifers (HF), of which 132 were Nellore (NEL), 76 were NEL × Angus crossbreds (NA), and 38 were NEL × Simmental crossbreds (NS). The right half carcass and the rib(9-11) from the left half carcass were analyzed for ether extract (EE), CP, and water. The remaining components were chemically analyzed to determine the composition of the body. A stepwise procedure was used to determine the variable inclusion in the regression models. The variables included were EE in the rib(9-11) (EER; %), CP in the rib(9-11) (CPR; %), water in the rib(9-11) (WR; %), visceral fat (VF; %; KPH and mesenteric fats), organs plus viscera (OV; %), carcass dressing percentage (CD; %), cold carcass weight (kg), and empty BW (EBW; kg). No sex or breed effects were found on EE and CP compositions of the carcass (C(EE) and C(CP), respectively; %); the equations were as follows: C(EE) = 4.31 + 0.31 × EER + 1.37 × VF [n = 241; R(2) = 0.83; mean square error (MSE) = 4.53] and C(CP) = 17.92 + 0.60 × CPR - 0.17 × CD (n = 238; R(2) = 0.50; MSE = 1.58). Breed affected water content in the carcass (C(W), %); the equations were as follows: C(W) = 48.74 + 0.28 × WR - 0.017 × EBW for NEL; C(W) = 46.69 + 0.32 × WR - 0.017 × EBW for NA; and C(W) = 38.06 + 0.48 × WR - 0.017 × EBW for NS (n = 243; R(2) = 0.67; MSE = 5.17). A sex effect was found on body chemical EE composition (BW(EE)); the equations were as follows: BW(EE) = 2.75 + 0.33 × EER + 1.80 × VF for BU; BW(EE) = 1.84 + 0.33 × EER + 1.91 × VF for STR; and BW(EE) = 4.77 + 0.33 × EER + 1.28 × VF for HF (n = 243; R(2) = 0.89; MSE = 3.88). No sex or breed effects were found on CP composition in the body (BW(CP)); the equation was as follows: BW(CP) = 14.38 + 0.24 × CPR (n = 240; R(2) = 0.59; MSE = 1.06). A sex effect was found for body water content (BW(W)); the equations were as follows: BW(W) = 38.31 + 0.33 × WR - 1.09 × VF + 0.50 × OV for BU; BW(W) = 45.67 + 0.25 × WR - 1.89 × VF + 0.50 × OV for STR; and BW(W) = 31.61 + 0.47 × WR - 1.06 × VF + 0.50 × OV for HF (n = 241; R(2) = 0.81; MSE = 3.84). The physical carcass composition indicated a breed effect on all components and a sex effect for fat in the carcass. We conclude that body and carcass compositions can be estimated with rib(9-11) for purebred and crossbred NEL animals, but specific equations have to be developed for different groups of animals.

Epigenetic clock analysis of diet, exercise, education, and lifestyle factors.

PubMed

Quach, Austin; Levine, Morgan E; Tanaka, Toshiko; Lu, Ake T; Chen, Brian H; Ferrucci, Luigi; Ritz, Beate; Bandinelli, Stefania; Neuhouser, Marian L; Beasley, Jeannette M; Snetselaar, Linda; Wallace, Robert B; Tsao, Philip S; Absher, Devin; Assimes, Themistocles L; Stewart, James D; Li, Yun; Hou, Lifang; Baccarelli, Andrea A; Whitsel, Eric A; Horvath, Steve

2017-02-14

Behavioral and lifestyle factors have been shown to relate to a number of health-related outcomes, yet there is a need for studies that examine their relationship to molecular aging rates. Toward this end, we use recent epigenetic biomarkers of age that have previously been shown to predict all-cause mortality, chronic conditions, and age-related functional decline. We analyze cross-sectional data from 4,173 postmenopausal female participants from the Women's Health Initiative, as well as 402 male and female participants from the Italian cohort study, Invecchiare nel Chianti.Extrinsic epigenetic age acceleration (EEAA) exhibits significant associations with fish intake (p=0.02), moderate alcohol consumption (p=0.01), education (p=3x10 -5 ), BMI (p=0.01), and blood carotenoid levels (p=1x10 -5 )-an indicator of fruit and vegetable consumption, whereas intrinsic epigenetic age acceleration (IEAA) is associated with poultry intake (p=0.03) and BMI (p=0.05). Both EEAA and IEAA were also found to relate to indicators of metabolic syndrome, which appear to mediate their associations with BMI. Metformin-the first-line medication for the treatment of type 2 diabetes-does not delay epigenetic aging in this observational study. Finally, longitudinal data suggests that an increase in BMI is associated with increase in both EEAA and IEAA.Overall, the epigenetic age analysis of blood confirms the conventional wisdom regarding the benefits of eating a high plant diet with lean meats, moderate alcohol consumption, physical activity, and education, as well as the health risks of obesity and metabolic syndrome.

Epigenetic clock analysis of diet, exercise, education, and lifestyle factors

PubMed Central

Lu, Ake T.; Chen, Brian H.; Ferrucci, Luigi; Ritz, Beate; Bandinelli, Stefania; Neuhouser, Marian L.; Beasley, Jeannette M.; Snetselaar, Linda; Wallace, Robert B.; Tsao, Philip S.; Absher, Devin; Assimes, Themistocles L.; Stewart, James D.; Li, Yun; Hou, Lifang; Baccarelli, Andrea A.; Whitsel, Eric A.; Horvath, Steve

2017-01-01

Behavioral and lifestyle factors have been shown to relate to a number of health-related outcomes, yet there is a need for studies that examine their relationship to molecular aging rates. Toward this end, we use recent epigenetic biomarkers of age that have previously been shown to predict all-cause mortality, chronic conditions and age-related functional decline. We analyze cross-sectional data from 4,173 postmenopausal female participants from the Women's Health Initiative, as well as 402 male and female participants from the Italian cohort study, Invecchiare nel Chianti. Extrinsic epigenetic age acceleration (EEAA) exhibits significant associations with fish intake (p=0.02), moderate alcohol consumption (p=0.01), education (p=3×10-5), BMI (p=0.01), and blood carotenoid levels (p=1×10-5)—an indicator of fruit and vegetable consumption, whereas intrinsic epigenetic age acceleration (IEAA) is associated with poultry intake (p=0.03) and BMI (p=0.05). Both EEAA and IEAA were also found to relate to indicators of metabolic syndrome, which appear to mediate their associations with BMI. Metformin—the first-line medication for the treatment of type 2 diabetes—does not delay epigenetic aging in this observational study. Finally, longitudinal data suggests that an increase in BMI is associated with increase in both EEAA and IEAA. Overall, the epigenetic age analysis of blood confirms the conventional wisdom regarding the benefits of eating a high plant diet with lean meats, moderate alcohol consumption, physical activity, and education, as well as the health risks of obesity and metabolic syndrome. PMID:28198702

School factors affecting postsecondary career pursuits of high-achieving girls in mathematics and science

NASA Astrophysics Data System (ADS)

Yoo, Hyunsil

This study examined the influences of secondary school experiences of high-achieving girls in math and science on their postsecondary career pursuits in science fields. Specifically, using the National Education Longitudinal Study of 1988 (NELS:88), the study investigated how science class experiences in high school affect science career persistence of high-achieving girls over and above personal and family factors. Selecting the top 10% on the 8 th grade math and science achievement tests from two panel samples of 1988--1994 and 1988--2000, this study examined which science instructional experiences (i.e., lecture-oriented, experiment-oriented, and student-oriented) best predicted college major choices and postsecondary degree attainments in the fields of science after controlling for personal and family factors. A two-stage test was employed for the analysis of each panel sample. The first test examined the dichotomous career pursuits between science careers and non-science careers and the second test examined the dichotomous pursuits within science careers: "hard" science and "soft" science. Logistic regression procedures were used with consideration of panel weights and design effects. This study identified that experiment-oriented and student-oriented instructional practices seem to positively affect science career pursuits of high-achieving females, while lecture-oriented instruction negatively affected their science career pursuits, and that the longitudinal effects of the two positive instructional contributors to science career pursuits appear to be differential between major choice and degree attainment. This study also found that the influences of instructional practices seem to be slight for general females, while those for high-achieving females were highly considerable, regardless of whether negative or positive. Another result of the study found that only student-oriented instruction seemed to have positive effects for high-achieving males. In addition, this study found that the lecture-oriented and experiment-oriented instructional practices were more likely to contribute to the choice of soft sciences for general and high-achieving females, while student-oriented instructional practices were more likely to contribute to the degree attainment in hard sciences for high-achieving females in science. The results should provide information for educational policies regarding school instruction and curriculum and career development targeted towards improving gender equity in science career pursuits.

IL TRAPIANTO ORTOTOPICO DEL FEGATO

PubMed Central

STARZL, THOMAS E.

2010-01-01

E’ormai noto che esiste la possibilità rivoluzionaria di utilizzare il fegato per il trattamento della stadio terminale delle epatopatie. Nel gennaio 1980 si celebra il decimo anna di sopravvivenza con fegato trapiantato (la più lunga della letteratura) di un paziente da noi trattato. Si tratta di uno dei 12 malati sottoposti a trapianto e seguiti per più di 5 anni. La nota positiva di questa tipo di trattamento è rappresentata dall’eccellente tenore di vita che i pazienti conducono e dalla riabilitazione sociale e professionale. La nota negativa è data, invece, dal fatto che i buoni risultati non vengono raggiunti con regolarità e non possono essere previsti con esattezza. In questa breve rassegna considereremo la esperienza da noi fatta presso l’Università di Denver nel Colorado, mettendo in risalto le cause dell’elevata mortalità precoce e le prospettive future di questa mezzo terapeutico. PMID:21572898

Augmenting Satellite Precipitation Estimation with Lightning Information

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mahrooghy, Majid; Anantharaj, Valentine G; Younan, Nicolas H.

2013-01-01

We have used lightning information to augment the Precipitation Estimation from Remotely Sensed Imagery using an Artificial Neural Network - Cloud Classification System (PERSIANN-CCS). Co-located lightning data are used to segregate cloud patches, segmented from GOES-12 infrared data, into either electrified (EL) or non-electrified (NEL) patches. A set of features is extracted separately for the EL and NEL cloud patches. The features for the EL cloud patches include new features based on the lightning information. The cloud patches are classified and clustered using self-organizing maps (SOM). Then brightness temperature and rain rate (T-R) relationships are derived for the different clusters.more » Rain rates are estimated for the cloud patches based on their representative T-R relationship. The Equitable Threat Score (ETS) for daily precipitation estimates is improved by almost 12% for the winter season. In the summer, no significant improvements in ETS are noted.« less

The Effectiveness of Acupuncture for Chronic Daily Headache: An Outcomes Study

DTIC Science & Technology

2009-12-01

1107 -t- 3 chan- nel transcutaneous electrical nerve stimulator ( TENS ) units. The negative or black lead was clipped onto the needle in.serted at...arc easily accessible for electrical tonification, especially for acupuncture naive subjects. They can also be used during an acute headache episode...ache, warmth, tingling, pressure, or radiation). Mild electrical tonification was applied to the 2 acu- puncture needles in tbe foot, using an ITO-IC

UNIVERSITY OF CALIFORNIA – CENTER FOR ENVIRONMENTAL IMPLICATIONS OF NANOTECHNOLOGY (UC-CEIN)

EPA Science Inventory

EPA GRANT NUMBER: 0830117
Title: University of California – Center for Environmental Implications of Nanotechnology (UC-CEIN)
Investigator: Andre E. Nel
Institution: University of California - Los Angeles
EPA Project Officer: Nor...

The energy and protein value of wheat, maize and blend DDGS for cattle and evaluation of prediction methods.

PubMed

De Boever, J L; Blok, M C; Millet, S; Vanacker, J; De Campeneere, S

2014-11-01

The chemical composition inclusive amino acids (AAs) and the energy and protein value of three wheat, three maize and seven blend (mainly wheat) dried distillers grains and solubles (DDGS) were determined. The net energy for lactation (NEL) was derived from digestion coefficients obtained with sheep. The digestible protein in the intestines (DVE) and the degraded protein balance (OEB) were determined by nylon bag incubations in the rumen and the intestines of cannulated cows. Additional chemical parameters like acid-detergent insoluble CP (ADICP), protein solubility in water, in borate-phosphate buffer and in pepsin-HCl, in vitro digestibility (cellulase, protease, rumen fluid) and colour scores (L*, a*, b*) were evaluated as potential predictors of the energy and protein value. Compared to wheat DDGS (WDDGS), maize DDGS (MDDGS) had a higher NEL-value (8.49 v. 7.38 MJ/kg DM), a higher DVE-content (216 v. 198 g/kg DM) and a lower OEB-value (14 v. 66 g/kg DM). The higher energy value of MDDGS was mainly due to the higher crude fat (CFA) content (145 v. 76 g/kg DM) and also to better digestible cell-walls, whereas the higher protein value was mainly due to the higher percentage of rumen bypass protein (RBP: 69.8 v. 55.6%). The NEL-value of blend DDGS (BDDGS) was in between that of the pure DDGS-types, whereas its DVE-value was similar to MDDGS. Although lower in CP and total AAs, MDDGS provided a similar amount of essential AAs as the other DDGS-types. Lysine content was most reduced in the production of WDDGS and cysteine in MDDGS. Fat content explained 68.6% of the variation in NEL, with hemicellulose and crude ash as extra explaining variables. The best predictor for RBP as well as for OEB was the protein solubility in pepsin-HCl (R 2=77.3% and 83.5%). Intestinal digestibility of RBP could best be predicted by ADF (R 3=73.6%) and the combination of CFA and NDF could explain 60.2% of the variation in the content of absorbable microbial protein. The availability of AAs could accurately be predicted from the rumen bypass and intestinal digestibility of CP.

Invited review: summary of steam-flaking corn or sorghum grain for lactating dairy cows.

PubMed

Theurer, C B; Huber, J T; Delgado-Elorduy, A; Wanderley, R

1999-09-01

Nineteen lactation trials (43 grain processing comparisons) are summarized, in addition to digestibility and postabsorptive metabolism studies. The net energy for lactation (NEL) of steam-flaked corn or sorghum grain is about 20% greater than the NEL for dry-rolled corn or sorghum. Based on lactational performance, steam-flaked sorghum grain is of equal value to steam-flaked corn, and steam-flaked corn is superior to steam-rolled corn. Steam-flaking of corn or sorghum compared to steam-rolling of corn or dry-rolling of corn or sorghum consistently improves milk production and milk protein yield. This result is because of a much greater proportion of dietary starch fermented in the rumen, enhanced digestibility of the smaller fraction of dietary starch reaching the small intestine, and increased total starch digestion. Steam-flaking increases cycling of urea to the gut, microbial protein flow to the small intestine, and estimated mammary uptake of amino acids. Steam-rolling compared to dry-rolling of barley or wheat did not alter total starch digestibilities in two trials, one with each grain source. Lactation studies with these processing comparisons have not been reported. Most cited studies have been with total mixed rations (TMR) and alfalfa hay as the principal forage. Additional studies are needed with lactating cows fed steam-flaked corn or sorghum in TMR containing alfalfa or corn silage. Optimal flake density of steam-processed corn or sorghum grain appears to be about 360 g/L (approximately 28 lb/bu).

Nextgen Navy eLearning Tracking

DTIC Science & Technology

2014-12-01

ELEARNING TRACKING by William E. Miller December 2014 Thesis Advisor: Man-Tak Shing Co-Advisor: Arijit Das THIS PAGE INTENTIONALLY LEFT......Navy’s eLearning (NeL) computer-based learning system relies on a Learning Management System (LMS) for content delivery and tracking learning

JPRS Report, East Europe.

DTIC Science & Technology

1988-03-02

months, an additional refrigeration storage plant with a freezer tun- nel. Using credit from the Swiss firm TRADAX, a horticultural combine in...it is not its therapeutic value, but rather that many mistakes have become clearer. The first mistake is that its proponents believed that the

Sviluppi di Ricevitori E di Componentistica Per Banda 3 mm Ad INAF-OA Cagliari

NASA Astrophysics Data System (ADS)

Navarrini, Alessandro

2017-11-01

L'INAF-OA Cagliari (OACa) sta sviluppando un ricevitore criogenico a basso rumore basato su un mixer SSB (Single Side Band) a superconduttore SIS (Superconductor-Insulator-Superconductor) per la banda 3 mm. Il ricevitore, acquistato da IRAM, è stato fortemente modificato per essere adattato al fuoco Gregoriano di SRT (Sardinia Radio Telescope). Lo strumento è caratterizzato da una nuova criogenia a ciclo chiuso 4 K (per evitare l'uso di elio liquido in antenna), da un nuovo oscillatore locale (di tipo ALMA Banda 3) e da un nuovo sistema di controllo e di monitoraggio basato su schede Raspberry ed Arduino sviluppato ad OACa. Verranno presentati i recenti sviluppi sul ricevitore, inclusi i risultati preliminari della misura della temperatura di rumore, che raggiunge un valore pari a Trec=66 K alla frequenza di 86 GHz, nonostante la criogenia non sia ancora ottimizzata. L'INAF-OACa è coinvolto nel progetto AETHRA (Advanced European Technologies for Heterodyne Receivers for Astronomy) nel quadro del programma Radionet/Horizon2020 per il quale sta contribuendo al WP1 (Work Package 1). Lo scopo del WP1 è di sviluppare e costruire un dimostratore di un array di ricevitori a doppia polarizzazione per la banda 3 mm basato su amplificatori criogenici a basso rumore (LNA) in tecnologia a semiconduttore MMIC. Nell'ambito del WP1 l'OACa ha in carico il progetto di un OrthomodeTransducer (OMT) in guida d'onda o in tecnologia planare per la banda 72-116 GHz che sia integrabile con amplificatori MMICs ed adatto all'integrazione in un array da installare nel piano focale di un radiotelescopio. Verranno presentati i design preliminari degli OMT per AETHRA, che sono basati su prototipi sviluppati in passato da OACa.

Aircraft Hydraulic Systems Dynamic Analysis

DTIC Science & Technology

1977-10-01

WHEQUT) for a Quincke tube resonator was revised. A similar subroutine was developed to simulate a hydraulic syscem acoustic filter available commer...input datt’l. Tlhe’ .il l t ’p. ol ý", nel-, r , ’li l t io (11 WAý: alq I SO ij•jI Ld t 0 t l• 11 ’ W11 I’ ( Quincke tube) subroutine. With these...studying pump hanger torque, precompression, decompression WHEQUT Subroutine 1) Revised, made corrections to, and ran Quincke tube subroutine (WHEQUT) b

Southeast Asia Report

DTIC Science & Technology

1986-08-19

Economic Minister Seeks Li eralized Imports (Julie C. Nel Castillo; BUSINESS DAY, 30 Jul 86) 25 IMF Agreement Blocks Intervention in Forex Market...IMF AGREEMENT BLOCKS INTERVENTION IN FOREX MARKET HK310416 Quezon City BUSINESS DAY in English 30 Jul 86 p 3 [By Daniel C. Yu] [Text] The government

Assessment of elder mistreatment in two American Indian samples: psychometric characteristics of the HS-EAST and the Native Elder Life-Financial Exploitation and -Neglect measures.

PubMed

Jervis, Lori L; Fickenscher, Alexandra; Beals, Janette

2014-04-01

Although elder mistreatment among ethnic minorities is increasingly gaining attention, our empirical knowledge of this phenomenon among American Indians remains quite limited, especially with respect to measurement. The Shielding American Indian Elders (SAIE) Project used a collaborative approach to explore culturally informed measurement of elder mistreatment in two American Indian elder samples (a Northern Plains reservation and a South Central metropolitan area). The project sought to investigate the performance characteristics of the commonly used Hwalek-Sengstock Elder Abuse Screening Test (HS-EAST), as well as to examine the psychometric properties of a new measure developed to capture culturally salient aspects of mistreatment in American Indian contexts--the Native Elder Life Scale (NELS). Using methods and samples comparable to those in the literature, the HS-EAST performed adequately in these Native samples. The NELS also shows promise for use with this population and assesses different aspects of elder mistreatment than does the HS-EAST.

U.S. EPA, Pesticide Product Label, , 05/08/1989

EPA Pesticide Factsheets

2011-04-21

... "'hare po •• 1bl •. ... ":" •• S 5?:-!:e":" n .. a=~. ;a:: .. r~~a .~~ ~. r, c~a:-g .. ra. ... Cont.et :rour !tate 'aatlelde or I:nel ron.ent.l Con:ro~ A9an:::T or Ha ...

The New Outspoken Atheism and Education

ERIC Educational Resources Information Center

Noddings, Nel

2008-01-01

In this essay, Nel Noddings calls upon U.S. public schools to equip students with a more nuanced understanding of religious vocabulary, history, and ideas. Examining recent books by outspoken atheists including Richard Dawkins, Daniel Dennett, Sam Harris, and Christopher Hitchens, Noddings argues that schools should help students "communicate…

Training Humans for the Human Domain

DTIC Science & Technology

2015-11-01

combat operations in Afghanistan had “been reduced by 60 percent since the scientists arrived in February [2007],” while Colo- nel David Woods of the...quested political asylum in the UK. With police and additional British Army personnel from another Scot - tish unit brought in to Bassingbourn to

ViNEL: A Virtual Networking Lab for Cyber Defense Education

ERIC Educational Resources Information Center

Reinicke, Bryan; Baker, Elizabeth; Toothman, Callie

2018-01-01

Professors teaching cyber security classes often face challenges when developing workshops for their students: How does one quickly and efficiently configure and deploy an operating system for a temporary learning/testing environment? Faculty teaching these classes spend countless hours installing, configuring and deploying multiple system…

United States Navy DL Perspective

DTIC Science & Technology

2010-08-10

United States Navy DL Perspective CAPT Hank Reeves Navy eLearning Project Director 10 August 2010 Report Documentation Page Form ApprovedOMB No...Marine Corps (USMC) Navy eLearning Ongoing Shared with USMC, Coast Guard 9 NeL Help Site https://ile-help.nko.navy.mil/ile/ https://s-ile

Aspetti deontologici e giuridici della Responsabilità professionale del chirurgo in Italia. Evoluzione storica a partire dal '900.

PubMed

Picardi, Nicola

2018-01-01

È pleonastico ricordare che ogni individuo raziocinante delle essere responsabile delle sue azioni: deve agire con la coscienza degli scopi che si propone evitando possibili conseguenze negative dei suoi atti. In ambito medico questo tipo di responsabilità è codificata con le norme della "deontologia". Per secoli l'arte terapeutica è stata praticata da individui dotati di una particolare vocazione ed una particolare cultura acquisita da Maestri dell'arte ancor prima che dalla propria esperienza, con nozioni di erboristeria e di elementari conoscenze anatomiche e di fisiologia, circondati da un'aura sacerdotale e da un rispetto derivante dal timore e dall'ammirazione per il coraggio e auspicabilmente dai successi, e facendo riferimento nell'occidente mediterraneo alle regole operative fissate nel Giuramento di Ippocrate, di significato tra il sacro ed il deontologico. Lo sviluppo delle tecniche anestesiologiche a partire dalla seconda metà dell'800 ha determinato l'ampliamento delle iniziative chirurgiche di tipo elettivo, a fianco con gli storici interventi in emergenza per la cura di lesioni traumatiche, ancor prima delle acquisizioni riguardanti le infezioni. Con l'espansione del campo di azione della chirurgia, le possibili complicanze ed i possibili insuccessi hanno fatto da contrappeso ai sentimenti di rispetto e di fiducia nei confronti dei chirurghi, giungendo a far assimilare in tali casi la loro opera quale causa all'origine di danni, provocati rientrando quindi nella categoria dei reati sottoposti alla Legge penale. Così, al termine deontologico di "responsabilità" valido per ogni iniziativa ed ogni professione, per i medici è venuto ad associarsi la qualifica di "professionale", con un significato di presunta colpevolezza. Da una parte le regole deontologiche si sono ampliate, ed hanno coinvolto direttamente il paziente nella fase decisionale delle terapie chirurgiche, formalizzate programmaticamente in moderni codici deontologici ed operativamente nel documento del "consenso informato". Per altro verso le leggi innovative del Codice Civile definito nel 1942, che al posto delle pene del codice penale introduceva il criterio della risarcibilità economica del danno in caso di riconosciuta "responsabilità professionale", ha determinato il coinvolgimento di altre figura professionali, e cioè di avvocati e di medici legali, oltre che delle organizzazioni assicurative, con detrimento alla serenità nell'espletamento delle professioni sanitarie e con l'insorgenza per reazione della cosidetta "medicina difensiva". La concretezza di queste problematiche hanno richiesto l'interessamento attivo della Giurisprudenza con una serie di sentenze, ed una formulazione di decreti e nuove leggi parlamentari, ancora in pieno assestamento nel corso del 2017, lasciano in qualche modo ancora irrisolti alcuni nodi.

Precollege science achievement growth: Racial-ethnic and gender differences in cognitive and psychosocial constructs

NASA Astrophysics Data System (ADS)

Muller, Patricia Ann

The purpose of this study was to gain a more complete understanding of the differences in science, mathematics and engineering education among racial-ethnic and gender subgroups by exploring factors related to precollege science achievement growth rates. Using Hierarchical Linear Modeling (HLM) and multi-wave, longitudinal data from the first three waves of the National Education Longitudinal Study of 1988--1994 (NELS:88/94), this study examined precollege science achievement growth rates during the 8th to 10th grade period and the 10th to 12th grade period for African American males, African American females, Latino males, Latina females, Asian American males, Asian American females, White males and White females. For the 8th--10th grade period, previous grades were significantly and positively related to science achievement growth for all subgroups; and socio-economic status and high school program were significantly and positively related to science achievement growth for all subgroups except one (Latino males, and Asian American males respectively). For the 10th--12th grade period, the quantity of science courses completed (science units) was the only variable that was statistically significant for more than one racial-ethnic by gender subgroup. Science units taken were significantly and positively related to 10 th--12th grade growth rates for all racial-ethnic by gender subgroups except Latino males. Locus-of-control was the only cognitive or psychosocial factor included from Eccles, Adler, Futterman, Goff, Kaczala, Meece and Midgley's (1983) theoretical framework for achievement behaviors that appeared to exhibit any pattern across race-ethnicities. Locus-of-control was positively related to 8th--10 th grade science achievement growth for females across all racial-ethnic subgroups, as well as for African American males. However, for both the 8 th--10th grade and 10th--12 th grade periods, there was no consistency across racial-ethnic or gender subgroups in effects of the remaining cognitive and psychosocial factors on science achievement growth rates. Cognitive and psychosocial variables were statistically significant only for specific subgroups, and did not generally exhibit any commonalities across gender, or by race. The findings accentuated the importance of disaggregating data and analyses by both race-ethnicity and gender.

Evaluation of Infrared Target Discrimination Algorithms.

DTIC Science & Technology

1983-04-01

application of this work is embodied in a computer program called PALANTIR , which Ref. 2 also describes in some detail. From a given set of narrow band spectral...chan- nels PALANTIR chooses a prescribed number of channels, picking those that will provide the least error when used in connection with a minimum

Transforming Ourselves/Transforming Curriculum: Spiritual Education and Tarot Symbolism

ERIC Educational Resources Information Center

Semetsky, Inna

2009-01-01

This paper is threefold. It is grounded in the philosophical work of two educational theorists: John Dewey and our contemporary Nel Noddings. It also brings into the conversation the ancient system of Tarot, arguing that its pictorial symbolism embodies intellectual, moral, and spiritual "lessons" derived from collective human experiences across…

USSR Report Military Affairs No. 1790.

DTIC Science & Technology

1983-08-17

tor- pedo and aviation depart- ments. The attending person- nel serving in the other subu- nits of a ship also play a signi- ficant role in...Yerakov and other officers, in a class on optical control, we watched a video recording of a past flying day: ^training flights, ground work, takeoff

Moral Life and Education

ERIC Educational Resources Information Center

Noddings, Nel

2016-01-01

Nel Noddings, Lee Jacks Professor of Education, Emerita, at Stanford University, agrees with Professors Lapsley and Woodbury that moral aims are central to education. She has argued that the main aim of education is to produce better people--better in "all aspects of a complete life: moral, physical, social, vocational, aesthetic,…

Framework for a Quantitative Systemic Toxicity Model (FutureToxII)

EPA Science Inventory

EPA’s ToxCast program profiles the bioactivity of chemicals in a diverse set of ~700 high throughput screening (HTS) assays. In collaboration with L’Oreal, a quantitative model of systemic toxicity was developed using no effect levels (NEL) from ToxRefDB for 633 chemicals with HT...

Calibrazioni a terra e prestazioni in volo di spettrometri ad immagine nel visibile e nel vicino infrarosso per l'esplorazione planetaria

NASA Astrophysics Data System (ADS)

Filacchione, Gianrico

2006-10-01

Nel corso dell’ultimo decennio l’esplorazione planetaria ha potuto beneficiare dei dati prodotti dagli spettrometri ad immagine: grazie a questa nuova classe di strumenti, realizzati per l’osservazione in remoto di superfici ed atmosfere planetarie, è possibile acquisire dati iperspettrali con elevati poteri risolutivi spaziali e spettrali. Il principale vantaggio offerto dagli spettrometri ad immagine, rispetto alle camere ed agli spettrometri puntuali, è rappresentato dalla capacità di misurare, identificare e mappare le unità composizionali delle superfici planetarie; queste informazioni permettono di investigare sia l’evoluzione geochimica delle superfici sia la dinamica e la composizione delle atmosfere. Sebbene i primi spettrometri ad immagine siano stati francesi (Phobos/ISM, Imaging Spectrometer for Mars) e statunitensi (Galileo/NIMS, Near Infrared Mapping Spectrometer), il nostro paese nel corso degli ultimi anni è stato in grado di proporre alla com unità spaziale internazionale degli strumenti dalle elevate prestazioni che sono stati infatti accettati come payload scientifici su diverse missioni interplanetarie: dai canali visibili di VIMS (Visual and Infrared Mapping Spectrometer) su Cassini (Nasa, JPL, ESA, ASI) e di OMEGA (Observatoire pour la Minéralogie, l’Eau, les Glacies et l’Activitè de Mars) su MarsExpress (ESA) ai due VIRTIS (Visible and Infrared Thermal Imaging Spectrometer) su Rosetta (ESA) e VenusExpress (ESA) fino a VIR-MS (Visible and Infrared Mapping Spectrometer) su Dawn (Nasa). In questo momento inoltre altri due spettrometri sono in avanzata fase di studio: JIRAM (Jovian InfraRed Auroral Mapper) su Juno (missione New Discovery Nasa) e VIHI (Visible and Infrared Hyperspectral Imager) integrato nel payload italiano di remote sensing SIMBIO-SYS di BepiColombo (missione cornerstone ESA). La realizzazione di uno spettrometro ad immagini da utilizzare su una missione interplanetaria richiede un’accurata analisi in fase progettuale e realizzativa dei parametri e de lle prestazioni strumentali; in generale infatti non solo sarà necessario mantenere le dimensioni, il peso, i consumi elettrici ed il data-volume entro i requisiti disponibili del satellite ma anche ottimizzare i disegni ottici, meccanici ed elettronici al fine di ottenere le massime prestazioni possibili in funzione della natura del target osservato e dei parametri orbitali della missione. Questa tesi descrive i metodi utilizzati per caratterizzare il funzionamento di spettrometri ad immagine per l’esplorazione planetaria. L’attività svolta ha riguardato sia la misura in laboratorio dei parametri strumentali fondamentali sia l’analisi dei dati in volo su cui verificarne ed eventualmente correggerne la risposta. Il funzionamento degli strumenti e la metodologia di calibrazione vengono descritti nelle due parti principali e nelle appendici di questa tesi per gli esperimenti Cassini-VIMS-V e Rosetta-VIRTIS-M. La prima parte è dedicata all’esperimento VIMS-V sul satellite Cassini, il cui disegno ottico, originariamente proposto da Francis Reininger, verrà successivamente riutilizzato e perfezionato su VIRTIS-M (Reininger et al., 1994; Miller et al., 1996). Il capitolo 1 contiene una descrizione dei parametri ottici, strutturali, termici ed elettronici di VIMS-V mettendone in risalto gli aspetti più innovativi del progetto. Vengono inoltre descritti la collocazione dell’esperimento sul satellite Cassini, il coallineamento con gli altri strumenti di remote sensing, i possibili modi operativi ed il formato dei dati scientifici. Il capitolo 2 riguarda il processo di calibrazione ed analisi dei dati in volo di VIMS-V. La procedura eseguita per calibrare radiometricamente lo strumento utilizzando i dati della superficie della Luna e per stimare il flat-field mediante i dati dell’atmosfera di Venere viene dettagliatamente descritta assieme agli algoritmi utilizzati per la rimozione di diversi effetti strumentali (read-out noise e tilt spettrale); alcuni di questi effetti sono stati caratterizzati e dettagliamente misurati in laboratorio utilizzando il modello spare (flight) di VIMS-V. Parte del capitolo è dedicata alla verifica della procedura di calibrazione su diversi target aventi caratteristiche spettroradiometriche note. Questi algoritmi di processamento sono correntemente utilizzati dal team scientifico di VIMS per calibrare i dati del canale -VIS rilasciati ufficialmente alla comunità scientifica internazionale attraverso il Planetary Data System (PDS) della Nasa. La seconda parte riguarda l’esperimento VIRTIS-M sul satellite Rosetta. Il capitolo 3 contiene la descrizione dello strumento mettendo in risalto l’evoluzione dal precedente progetto VIMS-V ed i problemi tecnologici e costruttivi da questo derivanti. I diversi modi operativi, la sequenza di acquisizione e di processamento dei dati nell’elettronica principale sono ampiament e discussi. Viene inoltre evidenziata la collocazione dello spettrometro sul satellite Rosetta. Nel capitolo 4 viene descritta l’attività di calibrazione effettuata in Galileo Avionica (Campi Bisenzio, FI, Italia) ed allo IAS (Orsay, Francia) subito dopo l’integrazione di VIRTIS ed il conseguente processamento dei dati necessario per ricavare i principali parametri di funzionamento (calibrazioni spettrali e geometriche, flat-field, funzioni di trasferimento, lampade di calibrazione interne). Nel capitolo 5 l’accuratezza di queste grandezze è stata verificata su i primi dati in volo ottenuti da VIRTIS-M durante la fase di commissioning e di cruise del satellite (Terra, Luna e Saturno); queste osservazioni sono inoltre state utilizzate per migliorare e verificare alcuni aspetti della procedura di calibrazione che non erano stati sufficientemente definiti durante i test a terra. L’appendice A riguarda il formato PDS (Planetary Data System) utilizzato per l’archiviazione dei dati e degli housekeepings ingegnerisitici e scientifici delle osservazioni; nell’appendice B è contenuta la descrizione del modello radiometrico teorico di VIRTIS-M utilizzato per stimare il rapporto segnale/rumore; nelle appendici C e D sono infine contenute diverse Tabelle non incluse nel testo delle parti principali a causa della loro lunghezza.

"Happiness and Education": Tilting at Windmills?

ERIC Educational Resources Information Center

Verducci, Susan

2013-01-01

This essay explores the question: Is Nel Noddings a visionary who sees past the constraints of contemporary education or is she, like Don Quixote, madly tilting at windmills in her description and defense of happiness as an educational aim? Viewing the educational aim of happiness as an ideal raises substantial challenges for the practicality of…

Conflicting Uses of "Happiness" and the Human Condition

ERIC Educational Resources Information Center

Fishman, Stephen M.; McCarthy, Lucille

2013-01-01

Nel Noddings claims that there is an important normative element in happiness. For support, she points to the Aristotelian idea of the "eudaimonic" life, a concept that is often translated into English as "the happy life". However, in light of the wide divergence between the Aristotelian view of "eudaimonia" as a life…

Essays on School Quality and Student Outcomes

ERIC Educational Resources Information Center

Crispin, Laura M.

2012-01-01

In my first chapter, I explore the relationship between school size and student achievement where, conditional on observable educational inputs, school size is a proxy for factors that are difficult to measure directly ( e.g., school climate and organization). Using data from the NELS:88, I estimate a series of value-added education production…

Peace Education: How We Come to Love and Hate War

ERIC Educational Resources Information Center

Noddings, Nel

2011-01-01

There is a huge volume of work on war and its causes, most of which treats its political and economic roots. In Loving and Hating War: An Approach to Peace Education, Nel Noddings explores the psychological factors that support war: nationalism, hatred, delight in spectacles, masculinity, religious extremism, and the search for existential…

A Flight Dynamic Model of Aircraft Spinning

DTIC Science & Technology

1990-06-01

r Zaw rate about body axes S Aircraft wing area V Flight path velocity 3 a Angle of attack Sideslip angle 6, Aileron deflection, positive when right...Tests, May/June 1983 PartI. Unpublished data report. 6. MARTIN, C.A. and SECOMB, D.A. ; RAAF BPTA Phase II Wind Tun - nel Tests: Rotary Balance Tests

An Empirical Test of Five Prominent Explanations for the Black-White Academic Performance Gap

ERIC Educational Resources Information Center

Oates, Gary L. St. C.

2009-01-01

The viability of five prominent explanations for the black-white performance gap ("academic engagement," "cultural capital," "social capital," "school quality" and "biased treatment") is examined using NELS data and a LISREL model that adjusts for clustering of students within schools. Empirical models have typically assessed these factors…

Quantitative Model of Systemic Toxicity Using ToxCast and ToxRefDB (SOT)

EPA Science Inventory

EPA’s ToxCast program profiles the bioactivity of chemicals in a diverse set of ~700 high throughput screening (HTS) assays. In collaboration with L’Oreal, a quantitative model of systemic toxicity was developed using no effect levels (NEL) from ToxRefDB for 633 chemicals with HT...

Caring in Teaching: A Complicated Relationship

ERIC Educational Resources Information Center

Barrow, Margaret

2015-01-01

This article addresses how developing caring relations with students at a community college effectively supports students' needs and ultimately success. At the same time, I discuss my own personal dilemmas while creating relationships that focus on students' needs. I use Nel Noddings' ethic of care theory to discuss how her ideas and the idea of…

75 FR 27372 - University of New Mexico; University of New Mexico AGN-201M Reactor; Environmental Assessment and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-14

... is housed in the Nuclear Energy Laboratory (NEL) located near the southwest corner of the University.... Therefore, license renewal should not change the environmental impact of facility operation. Data from the... analysis of human health and environmental impacts presented in this environmental assessment, the proposed...

Distanze dei pianeti e dei satelliti nel sistema solare dedotte da massa, raggio equatoriale e densità del corpo centrale.

NASA Astrophysics Data System (ADS)

Lupato, G.

1993-04-01

The author illustrates an empirical correlation linking planet distances from the Sun to some physical characteristics of the central body such as mass, equatorial radius, density. Such a formula is applicable, with good approximation, also to the major planet satellite systems.

[Trattamento della dipendenza da alcol. Alcol e giovani: punto di vista sociale].

PubMed

Alessandrini, Giovanni; Ciccarelli, Rosaria; Battagliese, Gemma; Lombardo, Giuseppe; De Rosa, Francesca; Messina, Marisa Patrizia; Vitali, Mario; Pisciotta, Fabiola; Nanut, Miriana; Attilia, Maria Luisa; Ceccanti, Mauro

2018-01-01

RIASSUNTO. Gli adolescenti rappresentano la fascia di età più vulnerabile ai danni causati dall'abuso di alcol, in quanto iniziare a bere in giovane età è associato a un aumento del rischio di dipendenza da alcolici in età adulta. I giovani tendono a bere grandi quantità di alcolici al fine di ricercare forti emozioni e nel tentativo di raggiungere il divertimento a ogni costo, tramite le proprietà psicotrope degli alcolici. Le cause che li inducono ad assumere questi comportamenti sono da ricercare nella non conoscenza degli effetti dannosi dell'alcol, nel rito di convivialità sociale (evenienza per la quale si attribuisce all'alcol la funzione di facilitatore dell'aggregazione tra giovani), nella mancanza di interessi personali, nella scarsità dei controlli e nelle abitudini familiari. Le azioni da intraprendere per limitare o arrestare il consumo nocivo di alcol nei giovani si devono basare su interventi finalizzati a ritardare l'età del primo contatto con le bevande alcoliche, mediante la realizzazione di campagne educazionali rivolte ai giovani stessi, ai loro familiari e alla società intera.

Identifying Voxels at Risk for Progression in Glioblastoma Based on Dosimetry, Physiologic and Metabolic MRI.

PubMed

Anwar, Mekhail; Molinaro, Annette M; Morin, Olivier; Chang, Susan M; Haas-Kogan, Daphne A; Nelson, Sarah J; Lupo, Janine M

2017-09-01

Despite the longstanding role of radiation in cancer treatment and the presence of advanced, high-resolution imaging techniques, delineation of voxels at-risk for progression remains purely a geometric expansion of anatomic images, missing subclinical disease at risk for recurrence while treating potentially uninvolved tissue and increasing toxicity. This remains despite the modern ability to precisely shape radiation fields. A striking example of this is the treatment of glioblastoma, a highly infiltrative tumor that may benefit from accurate identification of subclinical disease. In this study, we hypothesize that parameters from physiologic and metabolic magnetic resonance imaging (MRI) at diagnosis could predict the likelihood of voxel progression at radiographic recurrence in glioblastoma by identifying voxel characteristics that indicate subclinical disease. Integrating dosimetry can reveal its effect on voxel outcome, enabling risk-adapted voxel dosing. As a system example, 24 patients with glioblastoma treated with radiotherapy, temozolomide and an anti-angiogenic agent were analyzed. Pretreatment median apparent diffusion coefficient (ADC), fractional anisotropy (FA), relative cerebral blood volume (rCBV), vessel leakage (percentage recovery), choline-to-NAA index (CNI) and dose of voxels in the T2 nonenhancing lesion (NEL), T1 post-contrast enhancing lesion (CEL) or normal-appearing volume (NAV) of brain, were calculated for voxels that progressed [NAV→NEL, CEL (N = 8,765)] and compared against those that remained stable [NAV→NAV (N = 98,665)]. Voxels that progressed (NAV→NEL) had significantly different (P < 0.01) ADC (860), FA (0.36) and CNI (0.67) versus stable voxels (804, 0.43 and 0.05, respectively), indicating increased cell turnover, edema and decreased directionality, consistent with subclinical disease. NAV→CEL voxels were more abnormal (1,014, 0.28, 2.67, respectively) and leakier (percentage recovery = 70). A predictive model identified areas of recurrence, demonstrating that elevated CNI potentiates abnormal diffusion, even far (>2 cm) from the tumor and dose escalation >45 Gy has diminishing benefits. Integrating advanced MRI with dosimetry can identify at voxels at risk for progression and may allow voxel-level risk-adapted dose escalation to subclinical disease while sparing normal tissue. When combined with modern planning software, this technique may enable risk-adapted radiotherapy in any disease site with multimodal imaging.

Do the Groups to Which I Belong Make Me "Me"?: Reflections on Community and Identity

ERIC Educational Resources Information Center

Splitter, Laurance J.

2007-01-01

This article discusses the implications of some current philosophical thinking about groups, culture and the politics of identity (exploring the views of Anthony Appiah, Amartya Sen and Nel Noddings, among others) for education generally, and for issues of classroom organization in particular. My basic thesis is that, when we understand the…

Reconsidering Happiness in the Context of Social Justice Education

ERIC Educational Resources Information Center

Jackson, Liz; Bingham, Charles

2018-01-01

That happiness leads to lack of harm and suffering, representing both a good and a means to good, is promoted, for example, by educational philosophers such as Nel Noddings. But happiness should not be seen as an unproblematic goal, for education or otherwise. In this article, we critically investigate the importance of happiness in the…

Site Plan Safety Submission for Sampling, Monitoring and Decontamination of Mustard Agent, South Plant, Rocky Mountain Arsenal. Volume 1

DTIC Science & Technology

1988-10-01

agent areas and paints, causing the paint to peel , dissolve, or nel who do the visual inspections or place operations discolor, which may indicate...operated by licensed personnel. (6) Ensure that all downrange personnel have had their protective masks fit checked with amyl acetate ( banana oil). (7

Algebra? A Gate! A Barrier! A Mystery!

ERIC Educational Resources Information Center

Mathematics Educatio Dialogues, 2000

2000-01-01

This issue of Mathematics Education Dialogues focuses on the nature and the role of algebra in the K-14 curriculum. Articles on this theme include: (1) "Algebra For All? Why?" (Nel Noddings); (2) "Algebra For All: It's a Matter of Equity, Expectations, and Effectiveness" (Dorothy S. Strong and Nell B. Cobb); (3) "Don't Delay: Build and Talk about…

Touching the Challenge: Embodied Solutions Enabling Humanistic Moral Education

ERIC Educational Resources Information Center

Schwarz-Franco, Orit

2016-01-01

One of the main educational challenges we still face today--more than ever--is the humanistic challenge, namely how to promote humanistic moral values, how to strengthen in students the motivation to be morally active, and especially how to help them recognize the other as a human subject. I adopt Nel Noddings' approach of relational ethics of…

Risk Behaviors for Varying Categories of Disability in NELS:88

ERIC Educational Resources Information Center

Hollar, David

2005-01-01

A large body of research shows that youth with disabilities, who comprise about 13% of the country's school-aged population, report comparable to higher incidence rates of alcohol, tobacco, and other drug (ATOD) use than their peers. Furthermore, youth with disabilities who reported ATOD use or who engaged in binge drinking had significantly more…

Beyond Social Presence: Facelessness and the Ethics of Asynchronous Online Education

ERIC Educational Resources Information Center

Rose, Ellen

2017-01-01

In this position paper, I argue that a focus on achieving and increasing social presence in online courses tends to derail a consideration of the ethical implications and dimensions of the essential facelessness of asynchronous education. Drawing upon the work of Emmanuel Levinas and Nel Noddings, who contended that the face is the basis of…

Determinants of Academic Attainment in the United States: A Quantile Regression Analysis of Test Scores

ERIC Educational Resources Information Center

Haile, Getinet Astatike; Nguyen, Anh Ngoc

2008-01-01

We investigate the determinants of high school students' academic attainment in mathematics, reading and science in the United States; focusing particularly on possible differential impacts of ethnicity and family background across the distribution of test scores. Using data from the NELS2000 and employing quantile regression, we find two…

Physical function and self-rated health status as predictors of mortality: results from longitudinal analysis in the ilSIRENTE study.

PubMed

Cesari, Matteo; Onder, Graziano; Zamboni, Valentina; Manini, Todd; Shorr, Ronald I; Russo, Andrea; Bernabei, Roberto; Pahor, Marco; Landi, Francesco

2008-12-22

Physical function measures have been shown to predict negative health-related events in older persons, including mortality. These markers of functioning may interact with the self-rated health (SRH) in the prediction of events. Aim of the present study is to compare the predictive value for mortality of measures of physical function and SRH status, and test their possible interactions. Data are from 335 older persons aged >or= 80 years (mean age 85.6 years) enrolled in the "Invecchiamento e Longevità nel Sirente" (ilSIRENTE) study. The predictive values for mortality of 4-meter walk test, Short Physical Performance Battery (SPPB), hand grip strength, Activities of Daily Living (ADL) scale, Instrumental ADL (IADL) scale, and a SRH scale were compared using proportional hazard models. Kaplan-Meier survival curves for mortality and Receiver Operating Characteristic (ROC) curve analyses were also computed to estimate the predictive value of the independent variables of interest for mortality (alone and in combination). During the 24-month follow-up (mean 1.8 years), 71 (21.2%) events occurred in the study sample. All the tested variables were able to significantly predict mortality. No significant interaction was reported between physical function measures and SRH. The SPPB score was the strongest predictor of overall mortality after adjustment for potential confounders (per SD increase; HR 0.64; 95%CI 0.48-0.86). A similar predictive value was showed by the SRH (per SD increase; HR 0.76; 95%CI 0.59-0.97). The chair stand test was the SPPB subtask showing the highest prognostic value. All the tested measures are able to predict mortality with different extents, but strongest results were obtained from the SPPB and the SRH. The chair stand test may be as useful as the complete SPPB in estimating the mortality risk.

Prepartal Energy Intake Alters Blood Polymorphonuclear Leukocyte Transcriptome During the Peripartal Period in Holstein Cows

PubMed Central

Agrawal, A; Khan, MJ; Graugnard, DE; Vailati-Riboni, M; Rodriguez-Zas, SL; Osorio, JS; Loor, JJ

2017-01-01

In the dairy industry, cow health and farmer profits depend on the balance between diet (ie, nutrient composition, daily intake) and metabolism. This is especially true during the transition period, where dramatic physiological changes foster vulnerability to immunosuppression, negative energy balance, and clinical and subclinical disorders. Using an Agilent microarray platform, this study examined changes in the transcriptome of bovine polymorphonuclear leukocytes (PMNLs) due to prepartal dietary intake. Holstein cows were fed a high-straw, control-energy diet (CON; NEL = 1.34 Mcal/kg) or overfed a moderate-energy diet (OVE; NEL = 1.62 Mcal/kg) during the dry period. Blood for PMNL isolation and metabolite analysis was collected at −14 and +7 days relative to parturition. At an analysis of variance false discovery rate <0.05, energy intake (OVE vs CON) influenced 1806 genes. Dynamic Impact Approach bioinformatics analysis classified treatment effects on Kyoto Encyclopedia of Genes and Genomes pathways, including activated oxidative phosphorylation and biosynthesis of unsaturated fatty acids and inhibited RNA polymerase, proteasome, and toll-like receptor signaling pathway. This analysis indicates that processes critical for energy metabolism and cellular and immune function were affected with mixed results. However, overall interpretation of the transcriptome data agreed in part with literature documenting a potentially detrimental, chronic activation of PMNL in response to overfeeding. The widespread, transcriptome-level changes captured here confirm the importance of dietary energy adjustments around calving on the immune system. PMID:28579762

Language Characteristics and Academic Achievement: A Look at Asian and Hispanic Eighth Graders in NELS:88. Statistical Analysis Report.

ERIC Educational Resources Information Center

Bradby, Denise; And Others

This report examines the demographic and language characteristics and educational aspirations of Asian American and Hispanic American eighth graders and relates that information to their mathematical ability and reading comprehension as measured by an achievement test. Special attention is paid to students who come from homes in which a…

Army Sustainment. Volume 43, Issue 1, January-February 2011

DTIC Science & Technology

2011-02-01

pharmacist were even sent to the A medical Soldier wraps the feet of a child...requirements to supply person- nel. This helped the team to process demands for items that they were unfamiliar with. The pharmacist provided invaluable...Lieutenant General Daniel P. Bolger, the Army dep- uty chief of staff for operations, plans, and programs, said that the ability to conduct

Lista dei caratteri macroscopici per l’identificazione dei legni

Treesearch

Flavio Ruffinatto; Alan Crivellaro; Alex C. Wiedenhoeft

2016-01-01

L’identificazione dei legni costituisce il primo passo per ottenere conoscenze indispensabili in molti ambiti di studio. Ad esempio, prima di eseguire il restauro di un manufatto di interesse culturale è indispensabile conoscere il nome dei legni che lo compongono. Oppure, nel caso in cui si sospetti che un legno protetto da convenzioni internazionali sia stato...

Origini Concettuali di Errori che si Riscontrano Nel Confrontare Numeri Decimali e Frazioni=Conceptual Sources of Difficulties Concerning the Ordering of Decimal Numbers and the Comparison of Fractions.

ERIC Educational Resources Information Center

Bonotto, C.

1993-01-01

Examined fifth-grade students' survey responses to investigate incorrect rules that derive from children's efforts to interpret decimals as integers or as fractions. Regarding fractions, difficulties arise because only the whole-part approach to fractions is presented in elementary school. (Author/MDH)

Staircase Methods of Sensitivity Testing,

DTIC Science & Technology

1946-03-21

Mathematical Preliminaries ............. 32 b. Outline of the Investigation ..... .......... 35 8. The Possible Adjustments ...... ............... .. 36 9...bh Ar’Lied MathematIcs Pa-nel. ZCC, uU, -. for one decermntation !f tie per centtage point and the average nmber ee exp-li.-n. required far one such...accuracy per explosion. 32. II. TECOI4ICPJJ 7. Introduction. a. Some Mathematical Preliminaries. Expressed mathematically , the problem of sensitivity

Rethinking the Concept of Sustainability: Hiroshima as a Subject of Peace Education

ERIC Educational Resources Information Center

Ide, Kanako

2017-01-01

The article discusses a sustainable educational approach for developing a moral value of peace by using a historical event, the bombing of Hiroshima. To make the case, the article uses the care theory of Nel Noddings to discuss the interpersonal aspects of peace education. The article asks how care theory handles tragedies like Hiroshima and it…

Real-Time Optical Image Processing Techniques

DTIC Science & Technology

1988-10-31

pursued through the analysis, design, and fabrication of pulse frequency modulated halftone screens and the modification of micro-chan- nel spatial...required for non-linear operation. Real-time nonlinear processing was performed using the halftone screen and MSLM. The experiments showed the effectiveness...pulse frequency modulation has been pursued through the analysis, design, and fabrication of pulse frequency modulated halftone screens and the

Are School Uniforms a Good Fit? Results from the ECLS-K and the NELS

ERIC Educational Resources Information Center

Yeung, Ryan

2009-01-01

One of the most common proposals put forth for reform of the American system of education is to require school uniforms. Proponents argue that uniforms can make schools safer and also improve school attendance and increase student achievement. Opponents contend that uniforms have not been proven to work and may be an infringement on the freedom of…

Schooling for Democracy: A Common School and a Common University? A Response to "Schooling for Democracy"

ERIC Educational Resources Information Center

Reay, Diane

2011-01-01

This short paper is a response to Nel Noddings's article on schooling for democracy. Whilst agreeing with the basic premises of Noddings's argument, it questions the possibility of parity between academic and vocational tracks given the inequitable social and educational contexts the two types of learning would have to coexist within. Drawing on…

Inequalities at the Outset: Racial, Ethnic, and Socioeconomic Differences in Parents' Perceptions of Paying for College

ERIC Educational Resources Information Center

Warnock, Deborah M.

2016-01-01

Using NELS data I examine parents' perceptions of paying for college before their students enter high school. Findings suggest that racial wealth disparities may help explain differences in parents' perceptions of paying. In addition, Hispanics and low-income families are less likely to have information about financial aid and more likely to…

RBSE: Product development team research activity deliverables

NASA Technical Reports Server (NTRS)

1992-01-01

The GHG Functions and Extensions to be added to the NASA Electronic Library System (NELS) 1.1 product are described. These functions will implement the 'output request' capability within the Object Browser. The functions will be implemented in two parts. The first part is a code to be added to the Object Browser (X version) to implement menus allowing the user to request that objects be copied to specific media, or that objects be downloaded to the user's system following a specific protocol, or that the object be printed to one of the printers attached to the host system. The second part is shell scripts which support the various menu selections. Additional scripts to support functions within the GHG shell (X version) will also be created along with the X version of the GHG Shell as initial capability for the 27 Mar. prototype. The scripts will be composed of C shell routines that will accept parameters (primary file pathways). Certain limitations in functionality will invoke Mail instead of Oracle Mail since that has yet to be delivered and the NELS invocation will default to the X-Windows version instead of the ASCII version.

Il ruolo svolto dall’attività lavorativa sull’ipertensione arteriosa

PubMed Central

Barbini, N.; Gorini, G.; Ferrucci, L.; Biggeri, A.

2009-01-01

RIASSUNTO Introduzione I parametri di pressione arteriosa, sistolica (PAS) o diastolica (PAD) hanno costituito I’oggetto di numerosi studi, alcuni dei quali stabiliscono un’associazione tra I’aumnto di tali parametri e la mortalità, in particolare alle età medie. I fattori di rischio di ipertensione più frequentemente studiati sono il consumo di alcol, il fumo e I’origine etnica in riferimento sia alle differenze genetiche che nella condotta alimentare, mentre i fattori di origine professionale sono stati presi in considerazione più raramente e in maniera poco approfondita, inoltre sono state riferite notevoli differenze nelle pressioni arteriose medie di individui che svolgono professioni diverse. Sembra infatti che i “colletti blu” siano più a rischio dei “colletti bianchi”. Obiettivi Il nostro scopo è valutare se determinati rischi o vincoli connessi con l’attività professionale o determinati stili di vita rappresentano un fattore di rischio per l’ipertensione arteriosa in considerazioni dell’aumentare dell’età. Elementi specifici che rendano conto di questa relazione non sono stati ancora completamente chiariti e soprattutto i dati sulla popolazione italiana sono molto limitati. Metodi La metodologia di ricerca utilizzata è stata quella dell’indagine francese ESTEV (Derriennic, Touranchet, Volkoff) - VISAT (Marquie, Janson), studio epidemiologico longitudinale su oltre 23000 lavoratori attivata in Francia nel 1990 al fine di indagare gli effetti a lungo termine delle condizioni di lavoro, riferite all’intera vita professionale, sia sull’invecchiamento sia sulla salute dei lavoratori. Analoga indagine è stata avviata in Italia, nel 2000, in 6 Regioni, prendendo in esame i lavoratori dipendenti di diversi settori produttivi appartenenti a 5 coorti di età: da 32 a 52 anni con intervallo di 5 anni. Le rilevazioni sono state effettuate dai medici del lavoro di azienda attraverso 3 questionari: 1. sulle condizioni professionali (esposizione a determinati rischi o vincoli); 2. sugli stili di vita e la salute percepita secondo il Nottingham Health Profile; 3. sulle condizioni oggettive di salute. Per il presente lavoro saranno considerati solo alcuni parametri utili all’approfondimento epidemiologico nel settore cardiocircolatorio. Essi riguarderanno: 1) le condizioni di lavoro, 2) la valutazione soggettiva del lavoro, 3) costrizioni specifiche del lavoro vissute come più gravose con l’avanzare dell’età. Relativamente all’ipertensione, sono stati considerati ipertesi i soggetti che presentavano una PAS ≥160 mm/Hg e/o una PAD ≥90 mm/Hg nonché coloro in cura antipertensiva. Risultati I risultati si riferiscono a 1104 lavoratori, di cui 76% uomini e 24% donne. La prevalenza di ipertensione si è dimostrata più elevata nei maschi (33% Vs 22%). Le stime del rischio hanno evidenziato una associazione statisticamente significativa con alcuni fattori lavorativi come mantenere posture difficili (O.R. 1.71), lavorare in presenza di calore (O.R. 1.43), a contatto con agenti chimici (O.R, 1.31). stare a lungo seduti (O.R. 1.48), fare più cose contemporaneamente (O.R. 1.41), essere interrotti nel proprio lavoro (O.R. 1,35). non poter distogilere gli occhi dal lavoro (O.R.1.61). Conclusioni Noi abbiamo osservato che alcune caratteristiche fisiche del lavoro, ma soprattutto quelle di tipo organizzativo sono fortemente associate all’ipertensione arteriosa. Un elemento importante è sembrata la valutazione soggettiva del valore che i lavoratori danno del proprio lavoro: tale elemento è fortemente connesso con I’organizzazione del lavoro, pertanto è un possibile target di prevenzione (fattore di rischio modificabile). PMID:17886759

Distribution and Evolution of Yersinia Leucine-Rich Repeat Proteins

PubMed Central

Hu, Yueming; Huang, He; Hui, Xinjie; Cheng, Xi; White, Aaron P.

2016-01-01

Leucine-rich repeat (LRR) proteins are widely distributed in bacteria, playing important roles in various protein-protein interaction processes. In Yersinia, the well-characterized type III secreted effector YopM also belongs to the LRR protein family and is encoded by virulence plasmids. However, little has been known about other LRR members encoded by Yersinia genomes or their evolution. In this study, the Yersinia LRR proteins were comprehensively screened, categorized, and compared. The LRR proteins encoded by chromosomes (LRR1 proteins) appeared to be more similar to each other and different from those encoded by plasmids (LRR2 proteins) with regard to repeat-unit length, amino acid composition profile, and gene expression regulation circuits. LRR1 proteins were also different from LRR2 proteins in that the LRR1 proteins contained an E3 ligase domain (NEL domain) in the C-terminal region or an NEL domain-encoding nucleotide relic in flanking genomic sequences. The LRR1 protein-encoding genes (LRR1 genes) varied dramatically and were categorized into 4 subgroups (a to d), with the LRR1a to -c genes evolving from the same ancestor and LRR1d genes evolving from another ancestor. The consensus and ancestor repeat-unit sequences were inferred for different LRR1 protein subgroups by use of a maximum parsimony modeling strategy. Structural modeling disclosed very similar repeat-unit structures between LRR1 and LRR2 proteins despite the different unit lengths and amino acid compositions. Structural constraints may serve as the driving force to explain the observed mutations in the LRR regions. This study suggests that there may be functional variation and lays the foundation for future experiments investigating the functions of the chromosomally encoded LRR proteins of Yersinia. PMID:27217422

The Perfection of the Teacher through the Pursuit of Happiness: Cavell's Reading of J. S. Mill

ERIC Educational Resources Information Center

Takayanagi, Mitsutoshi

2016-01-01

Drawing upon Nel Noddings' contention that, if children are to be happy in schools, their teachers should also be happy, this paper tries to explore a way in which the obviously intimate but seemingly conflicting connections between students' and teachers' happiness can be understood from the viewpoint of Stanley Cavell's reading of J. S. Mill.…

Company Command: The Bottom Line

DTIC Science & Technology

1990-11-20

who engage in original research on national security issues. NDU Press publishes the best of this research . In addition, the Press publishes other...79 Stan dard Inslallation/Division Person-. nel Systems jSIDPERS)-SIDPEiIS Be- p orts- Non coinmmission ed Officer Evaluation fleports (NO-ERs--Offtcer... Non - combatant Evacuation Operation (NEO) xii and Prenaration for Overseas Moveizent (PO.MW-Finance The Bottom Line for Personnel and Administration

Trust-Management, Intrusion-Tolerance, Accountability, and Reconstitution Architecture (TIARA)

DTIC Science & Technology

2009-12-01

Tainting, tagged, metadata, architecture, hardware, processor, microkernel , zero-kernel, co-design 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF... microkernels (e.g., [27]) embraced the idea that it was beneficial to reduce the ker- nel, separating out services as separate processes isolated from...limited adoption. More recently Tanenbaum [72] notes the security virtues of microkernels and suggests the modern importance of security makes it

Attivita del Centro di Linguistica Applicata nel campo della lingua e della cultura italiana all'estero (Activities of the Italian Center for Applied Linguistics concerning Italian Language and Culture Abroad).

ERIC Educational Resources Information Center

Boriosi Katerinov, Maria Clotilde

1979-01-01

Outlines the activities of a recently created section of the Italian Center for Applied Linguistics (CILA), dealing with "Teaching Italian Abroad." Describes these activities as encompassing four areas: research, teaching methodology, consultation, teachers' training and bibliographical information. Lists statistical surveys, research papers, and…

Optimization of an Internally Finned Rotating Heat Pipe.

DTIC Science & Technology

1980-09-01

ICALC.GT~lI GO TO 1.0 C ** INPUT MODE *** C ELEMENT CONNECTIVITIES C READ (5,-420) NELOSNPANBAN WRITE (6,430) NELNSNl ,NBAN READ (5,440) ( IELt (ICOR(IEL,1...I=1,3),IEL=1,NEL) CWRITE (6,450) C wRITE(6,251) ( IELt (ICOR(IEL,IbtI=1,3), IELINEL) C C TihE CONDENSER GEOMETRY C READ (5,46C) CLI CANGL,RBASEI R21

OPSATCOM Field Measurements. Volume 1

DTIC Science & Technology

1976-06-01

ADVANCED RESEARCH PROJECTS AGENCY AF SPACE & MISSILE SYSTEMS ORGANIZATION -. TECHNICAL ý IBRARY (3) SKX (DR. D. BARRY) (3) OFFICE OF THE IRECTOR OF DEFENSE...FORCE CAMBRIDGE kL.LSEARCH CENTER DEFENs r FELFC’OMMUNICATI[NS& COMMAND & tECHNICAL LIBRAHY r’ONTROL SYSTEMS NATIONAL AERONAUTICS AND SPACE...STREET T NAVAL. ELECTRONIC SYSTEMS COMMAND SANTA MONICA, CA 90496 NELEX.031031 IT. B. HUGHES) (3) UNIVERSITY OF CALIFORNIA, SAN DIEGO NEL X 3102 (M

Competence: Analysis, Critique, Reassessment. A Report of a Conference Held May 18-20, 1980, under the Auspices of the College of Education, the Pennsylvania State University.

ERIC Educational Resources Information Center

Short, Edmund C.

A report provides summaries of 10 papers presented at a conference about teacher competence and effectiveness. In the first session, two speakers, Nel Noddings and Edward R. Fagan, present an analysis of the prevailing rhetoric in educational discourse and practice. The second session provides historical perspectives on the use of the term…

Asteroidi

NASA Astrophysics Data System (ADS)

Foglia, Sergio; Morbidelli, Alessandro; Masi, Gianluca; Carusi, Andrea

2006-10-01

Contents: Parte I: Asteroidi. 1. Introduzione. 2. Dinamica degli asteroidi. 3. Distribuzione degli asteroidi. 4. Proprietà fisiche degli asteroidi. 5. Interrelazioni nel Sistema Solare. Parte II: Le Osservazioni. 6. La pianificazione. 7. Astrometria. 8. Fotometria. Appendici: A. Tempo delle Effemeridi e Tempo Universale. B. Calcolo Effemeridi. C. Guida all'utilizzo del Minor Planet Software rel. 8. D. Determinazione della Coordinate Geografiche di una postazione di osservazione dalle Coordinate Metriche U.T.M. nella principale cartografia italiana.

[Trattamento della dipendenza da alcol. Alcol e persone senza fissa dimora: punto di vista sociale].

PubMed

Alessandrini, Giovanni; Ciccarelli, Rosaria; Battagliese, Gemma; Cereatti, Federica; Gencarelli, Simona; Messina, Marisa Patrizia; Vitali, Mario; De Rosa, Francesca; Ledda, Roberta; Mancini, Serena; Attilia, Maria Luisa

2018-01-01

RIASSUNTO. Il fenomeno delle persone senza fissa dimora sta assumendo in questi anni una rilevanza sociale devastante, con una prevalenza stimata in USA e in Europa compresa tra il 5,6% e il 13,9%. Queste persone hanno una scarsa qualità di vita, una limitata o assente vita sociale, sono spesso disoccupate o lavorano solo saltuariamente. Sono a rischio di problemi con la legge, sono spesso affette da dipendenza da droghe, da patologie psichiatriche e internistiche. L'alcol spesso non rappresenta la causa della loro condizione sociale, ma solo la conseguenza, contribuendo in questo modo al loro degrado bio-psico-sociale. Nel 2009 lo US Department of Housing and Urban Development's Homelessness Assistance Programs e nel 2010 la European Consensus Conference on Homelessness hanno segnato un grande passo avanti nella riabilitazione sociale di queste persone, utilizzando il concetto del "case management". In particolare lo Standard Case Management si è dimostrato in grado di migliorare la stabilità abitativa, di ridurre l'uso di droghe e di rimuovere le barriere lavorative. L'Assertive Community Treatment si è dimostrato, invece, in grado di migliorare la stabilità abitativa e ha un rapporto costo/beneficio migliore per i pazienti affetti da doppia diagnosi.

New Trends in Gender and Mathematics Performance: A Meta-Analysis

PubMed Central

Lindberg, Sara M.; Hyde, Janet Shibley; Petersen, Jennifer L.; Linn, Marcia C.

2010-01-01

In this paper, we use meta-analysis to analyze gender differences in recent studies of mathematics performance. First, we meta-analyzed data from 242 studies published between 1990 and 2007, representing the testing of 1,286,350 people. Overall, d = .05, indicating no gender difference, and VR = 1.08, indicating nearly equal male and female variances. Second, we analyzed data from large data sets based on probability sampling of U.S. adolescents over the past 20 years: the NLSY, NELS88, LSAY, and NAEP. Effect sizes for the gender difference ranged between −0.15 and +0.22. Variance ratios ranged from 0.88 to 1.34. Taken together these findings support the view that males and females perform similarly in mathematics. PMID:21038941

Southeast Asia Report.

DTIC Science & Technology

1987-04-01

such as palm oil and coconut oil . In 1985, for example, Malaysia alone exported 470,887 tonnes of palm oil and palm ker- nel oil to the EEC valued...SOUTHEAST ASIA REPORT CONTENTS INTER-ASIAN AFFAIRS ASEAN To Protest EEC Duties on Vegetable Oils , Fats (Hardev Kaur; BUSINESS TIMES, 18 Feb 87) 1...DAN (TAP CHI QUAN DOI NHAN DAN, Dec 86) 112 /12223 - f - ASEAN TO PROTEST EEC DUTIES ON VEGETABLE OILS , FATS Kuala Lumpur BUSINESS TIMES in

Does a Sentiment-Based Ethics of Caring Improve upon a Principles-Based One? The Problem of Impartial Morality

ERIC Educational Resources Information Center

Johnston, James Scott

2008-01-01

My task in this paper is to demonstrate, contra Nel Noddings, that Kantian ethics does not have an expectation of treating those closest to one the same as one would a stranger. In fact, Kantian ethics has what I would consider a robust statement of how it is that those around us come to figure prominently in the development of one's ethics. To…

An Analysis of Emergency Department Overcrowding at The Johns Hopkins Hospital

DTIC Science & Technology

2001-06-20

Jefferson 3rd floor (JEF3), Medical Care Progressive Unit ( MPC4 ), Nelson 4th floor (NEL4), Osler 4th floor (OSL4), Osler 5th floor (OSL5), and Osler...ranged from a low of 73.78% for OSL5 to a high of 94.60% for JEF3. The LOS for the DOM units ranged from 2.89 days for HAL5 to 10.39 days for MPC4

Upper Atmosphere Research Report Number 2

DTIC Science & Technology

1946-12-30

Laboratory personnel working under the direction 0-@. of U. S . Armj Ordnance and General Electric Company personnel. 45. *6 A", ., . . . . __V s ;... r.r.r...thanks are due to U. S . Army ordnance and General Electric Company person- nel for making the fin installation possible and for aid in recovering the...CONDUCTED IN THE-V-2 •....... . . . . . . A. Solar Spectroscopy - F. S . Johnson, J. J. Oberly, C. V. Strain and Re Tousey........ 44 1. Introduction

Il sistema multiplo di Spica osservato dal Padre Giovanni Battista Audiffredi nel 1753

NASA Astrophysics Data System (ADS)

Sigismondi, Costantino

2005-06-01

The multiplicity of Spica's system has been first observed in 1753 by the dominican father Giovanni Battista Audiffredi through a lunar occultation. Audiffredi noted that the emersion's duration from the bright lunar limb was not instantaneous. Nowadays Spica has five known components, four of them have been discovered by occultation. This observation is presented along with a general introduction of lunar occultations, Watts' profiles, Cassini regions and grazes.

Cooperation Helps Power Saving

DTIC Science & Technology

2009-04-07

the destination node hears the poll, the link between the two nodes is activated. In the original STEM, two radios working on two separate channels... hears the poll, the link between the two nodes is activated. In the original STEM, two radios working on two separate chan- nels are used: one radio is...Computer and Communications Societies. Proceedings. IEEE, vol. 3, pp. 1548–1557 vol.3, 2001. [2] R . Kravets and P. Krishnan, “Application-driven power

How to Select a Good Training-data Subset for Transcription: Submodular Active Selection for Sequences

DTIC Science & Technology

2009-01-01

selection and uncertainty sampling signif- icantly. Index Terms: Transcription, labeling, submodularity, submod- ular selection, active learning , sequence...name of batch active learning , where a subset of data that is most informative and represen- tative of the whole is selected for labeling. Often...representative subset. Note that our Fisher ker- nel is over an unsupervised generative model, which enables us to bootstrap our active learning approach

Aortopexy for the treatment of tracheomalacia in children: review of the literature

PubMed Central

2012-01-01

Abstract Severe tracheomalacia presents a significant challenge for Paediatricians, Intensivists, Respiratory Physicians, Otolaryngologists and Paediatric Surgeons. The treatment of tracheomacia remains controversial, but aortopexy is considered by most to be one of the best options. We conducted a review of the English literature relating to aortopexy. Among 125 papers, 40 have been included in this review. Among 758 patients (62% males) affected with tracheomalacia, 581 underwent aortopexy. Associated co-morbidities were reported in 659 patients. The most frequent association was with oesophageal atresia (44%), vascular ring or large vessel anomalies (18%) and innominate artery compression (16%); in 9% tracheomalacia was idiopathic. The symptoms reported were various, but the most important indication for aortopexy was an acute life-threatening event (ALTE), observed in 43% of patients. The main preoperative investigation was bronchoscopy. Surgical approach was through a left anterior thoracotomy in 72% of patients, while median approach was chosen in 14% and in 1.3% a thoracoscopic aortopexy was performed. At follow-up (median 47 months) more than 80% of the patients improved significantly, but 8% showed no improvement, 4% had a worsening of their symptoms and 6% died. Complications were observed in 15% of patients, in 1% a redo aortopexy was deemed necessary. In our review, we found a lack of general consensus about symptom description and evaluation, indications for surgery, though ALTE and bronchoscopy were considered by all an absolute indication to aortopexy and the gold standard for the diagnosis of tracheomalacia, respectively. Differences were reported also in surgical approaches and technical details, so that the same term “aortopexy” was used to describe different types of procedures. Whatever approach or technique was used, the efficacy of aortopexy was reported as high in the majority of cases (more than 80%). A subgroup of patients particularly delicate is represented by those with associated gastro-esophageal reflux, in whom a fundoplication should be performed. Other treatments of tracheomalacia, particularly tracheal stenting, were associated with a higher rate of failure, severe morbidity and mortality. Non english abstract La tracheomalacia severa rappresenta una sfida per Pediatri, Intensivisti, Pneumologi, Otorinolaringoiatri, Chirurghi Pediatri. Il trattamento della tracheomalacia è tuttora controverso. L’aortopessi è considerata da molti la migliore opzione terapeutica. Abbiamo condotto una revisione della letteratura di lingua inglese su tale argomento. Di 125 lavori, 40 sono stati inclusi nella revisione. Tra 758 pazienti (62% maschi) affetti da tracheomalacia, 581 sono stati sottoposti ad aortopessi tra il 1968 e il 2008. In 659 pazienti alcune comorbidità erano presenti. L’associazione più frequente era con l’atresia esofagea (44%), l’anello vascolare o un’anomalia dei grossi vasi (18%), la compressione da parte dell’arteria innominata (16%); nel 9% la tracheomalacia era idiopatica. I sintomi riportati sono stati variabili, ma l’indicazione più importante all’aortopessi sono stati eventi di ALTE, osservati nel 43% dei pazienti. Lo studio diagnostico preoperatorio principale è stato la broncoscopia. L’approccio chirurgico è avvenuto attraverso una toracotomia anteriore sinistra nel 72% dei pazienti, mentre un approccio mediano è stato scelto nel 14% e nell’1.3% dei casi è stato eseguito un approccio toracoscopico. Al follow-up (mediana di 47 mesi) la maggioranza dei pazienti sono migliorati significativamente, ma l’8% di essi non è migliorato, il 4% è peggiorato e il 6% è morto. Complicazioni sono state riportate nel 15% dei pazienti, nell’1% un nuovo intervento di aortopessi è stato necessario. In questa revisione abbiamo trovato che non c’è un consenso generale sulla valutazione e sulla descrizione dei sintomi, sulle indicazioni chirurgiche ed esami preoperatori, anche se le ALTE e la broncoscopia venivano considerate rispettivamente un’indicazione assoluta all’aortopessi e il “gold standard” diagnostico per la tracheomalacia. Venivano riportate differenze negli approcci chirurgici e nei dettagli tecnici, e lo stesso termine di aortopessi veniva usato per indicare diverse procedure chirurgiche. In ogni caso, indipendentemente dall’approccio o tecnica utilizzati, l’efficacia dell’aortopessi veniva riportata come elevata nella maggioranza dei casi (più dell’80%). Un sottogruppo di pazienti particolarmente delicato è rappresentato da quelli con reflusso gastroesofageo associato, nei quali sarebbe indicata una fundoplicatio. Altri trattamenti della tracheomalacia, quali stent tracheale, sembrano gravati da una maggiore percentuale di insuccessi, morbidità severa e mortalità. PMID:23110796

[Assessment of a project for integrated management of care given to patients with type-2 diabetes in the Local Health Authority 21 of Legnago (Veneto Region, Northern Italy) in the period 2010-2012].

PubMed

Marcon, Alessandro; Vaona, Alberto; Rigon, Giulio; Carazzolo, Marco; Del Zotti, Franco; Girotto, Sandro; Marafetti, Claudio

2016-01-01

OBIETTIVI: descrivere, nella ASL 21 di Legnago (VR), l'andamento di alcuni indicatori sanitari tra il 2009, anno precedente all'avvio di un progetto triennale per la gestione integrata dell'assistenza al paziente con diabete mellito di tipo 2, e il 2012, ultimo anno del progetto. DISEGNO: studio longitudinale trasversale ripetuto. SETTING E PARTECIPANTI: tutti i pazienti diabetici di tipo 2 della ASL 21, identificati nei database aziendali (in base a esenzioni per patologia, accessi al servizio diabetologico, consumo di farmaci antidiabetici e strisce per la determinazione della glicemia) e nelle cartelle cliniche dei medici di famiglia. PRINCIPALI MISURE DI OUTCOME: numero di test diagnostici e di follow-up erogati, consumo di farmaci, prestazioni specialistiche, accessi al pronto soccorso, ricoveri e mortalità. RISULTATI: nonostante un calo generalizzato (-3,1%) nei test erogati dalla ASL 21 ai suoi assistititi nel periodo 2009-2012, l'analisi ha documentato un marcato aumento per gli esami previsti nella gestione del diabete, quali curve da carico glicemico (+104,3%), emoglobina glicata (+19,0%) e microalbuminuria (+296,1%). I soggetti identificati come diabetici sono aumentati da 8.084 nel 2009 (5,2%) a 9.221 nel 2012 (5,9%). Sono stati osservati aumenti nella prevalenza di pazienti visitati presso un servizio diabetologico (dal 22,6% al 39,0%), nonché negli utilizzatori di metformina (dal 28,0% al 37,5%), insuline (dal 13,5% al 18,3%) e incretine (dall'1,4% al 9,0%). Il consumo di sulfaniluree è, invece, calato (dal 49,9% al 40,8%), come anche l'erogazione di alcune prestazioni specialistiche, gli accessi al pronto soccorso e i ricoveri, mentre il tasso di mortalità è rimasto stabile (29,6 decessi x1.000/anno). CONCLUSIONE: durante il periodo di implementazione del progetto sembra essersi verificato un aumento della sensibilità diagnostica e una maggiore presa in carico del paziente diabetico. Anche se la natura osservazionale dello studio non consente di dimostrare una relazione causa-effetto, i risultati sembrano supportare l'ipotesi che la gestione integrata della patologia migliori l'appropriatezza dell'assistenza.

Preliminary Evaluation of an Algorithm for Analysis of Stationary Random Data from a Multiple-Input Linear System.

DTIC Science & Technology

1979-07-01

nel for low-frequency filters with Lg92/Lgl = 4.4 for S/N1 = 1. 71. CASE 1, S/NF= 1, S/I1 1 M=5 M1=10 M1=20 C! a ip a a a a 00 2 3Ma a0 0 M𔃺 M 3...Gantmacher, The Theory of Matrices, VoZ . 1, Chelsea Publishing Co., New York, NJ.Y., 1959. 163

Advanced Teleprocessing Systems.

DTIC Science & Technology

1984-09-30

up delay depends on the amount of work (or the number of customers) ar- riving to the system at the beginning of the start-up period. 2) A system...types of systems are analyzed: 1) A system where the start-up delay depends on the amount of work (or the number of customers) ar- riving to the system...net- work where terminals are randomly distributed on the plane, are able to capture transmitted signals, and use slotted ALOHA to access the chan- nel

The Russian Military and the Georgia War: Lessons and Implications

DTIC Science & Technology

2011-06-01

establish- ing direct government-to-government contact with the unofficial governments in Abkhazia and South Os- setia , a step that Georgia claimed amounted...the peacekeeping forces in Abkhazia and South Os- setia , arguing that Russia had become a party to the conflict and therefore was unsuited to its...length of the highway from the army’s garrison in Vladikavkaz to the Roki Tun- nel, the only road avenue of approach into South Os- setia .17 While

Common Violations of the United States Code in Economic Crime Investigations. The Fraud, Waste and Abuse Monster.

DTIC Science & Technology

1983-11-15

person- nel in understanding the elements of the offense and the evidence necessary to establish or negate probable cause. For the benefit of OCONUS...gift, favor, entertainment, hospitality, transportation, loan, or other tangible benefit for which less than fair market value is paid. c...influenced. He may even refuse the offer, yet the offense is complete. Nor need the thing of value personally benefit the public official. However, the

Nourishing the Spirit, Reflection and Dialogue with Our Students on the Question of Intelligent Design: What Are We Likely to Encounter and How Might We Proceed?

ERIC Educational Resources Information Center

Zigler, Ronald Lee

2009-01-01

In her 1993 text "Educating For Intelligent Belief and Unbelief," Nel Noddings advocated an ambitious plan to challenge the students; she wished to engage them in a dialogue on the religious issues that define those questions, which "matter deeply to everyone." This was seen as a dialogue that can take place at all levels of education, but was…

Recruiting Policies and Practices for Women in the Military: Views From the Field

DTIC Science & Technology

2017-01-01

enough to apply for Office of Management and Budget clearance, which takes a minimum of six months and is required when federal funds are used to...Evelyn Dyer, Office of the Under Secretary of Defense for Personnel and Readiness/Readiness and Force Management /Military Person- nel Policy... Management and Budget OSD Office of the Secretary of Defense OUSD/P&R Office of the Under Secretary of Defense for Personnel and Readiness STEM science

Noise Effects Upon a Simple Timing Channel

DTIC Science & Technology

1990-12-21

used to quantify the resulting information flow across the chan- nel. Possible Trojan Horse strategies are also discussed. 14. SUBJECT TERMS 15. NUMBER...performed by a program referred to as a Trojan Horse . The Trojan Horse has the ability to instigate the delaying procedure to low, read high’s file. code it...and pass it through this delaying procedure. Such a means of communication between high and low, with or without the Trojan Horse in place, will be

Workshop on Permafrost Geophysics Held at Golden, Colorado on 23-24 October 1984.

DTIC Science & Technology

1985-05-01

south, southwest and northeast of Tuktoyaktuk Harbour and around Mallik Bay near Illisarvik. Ice contents are low to medi- * -’ um, with the ice...morainal deposits, to the southwest and northeast of Tuktoyaktuk and to the south of Mallik Bay. Massive ice of segregation and intrusive origin is...the southeast side of Mallik Bay, alongside Swan Channel and beneath the alluvial islands west of Mallik Chan- U nel. The map unit is less extensive

Dual Career Families within the Coast Guard Officer Corps.

DTIC Science & Technology

1981-09-01

as a Result of Your Combined Career/Job?............... 59 Table 4.15 What Would H-appen to Spouse’s Career if You were Transferred to a New Duty...children only represents seven percent of American households (U.S. News and World Report, 1979169). Eli Ginzberg, a Columbia University economist has...career which is mori compatible with his spouses. Because of the current shortage of personnel and the high cost of training new person- nel, more

Latinos in science: Identifying factors that influence the low percentage of Latino representation in the sciences

NASA Astrophysics Data System (ADS)

Miranda, Susan Jennifer

A mixed methods approach was used to identify factors that influence the underrepresentation of Latinos in the domain of science. The researcher investigated the role of family influences, academic preparation, and personal motivations to determine science-related career choices by Latinos. Binary logistic regression analyses were conducted using information from Latinos gathered from the National Education Longitudinal Study of 1988 (NELS: 88) administered by the National Center for Education Statistics. For the present study, data were analyzed using participants' responses as high school seniors, college students, and post-baccalaureates. Students responded to questions on school, work, parental academic influences, personal aspirations, and self-perception. To provide more insight into the experiences of Latinos in science and support the statistical analyses, nine students majoring in science in a private, urban university located in the northeastern part of the country were interviewed. Eleven variables related to parents' academic support and students' perceptions of parental support were taken together as predictors for two separate criteria from the survey. These results identified parents' level of education and the importance of academics to parents in their teen's college choice as significant predictors in determining college major in science. When the criterion was degree in science, the significant predictor was the frequency parents contacted high school as volunteers. Student interviews supported this information, demonstrating the importance of parental support in attaining a degree in science. Academic preparation was also analyzed. Students' reasons for taking science classes in high school was a significant predictor for science major; significant predictors for science degree were the emphasis placed on objectives in math and science classes and number of courses in biology and physics. Student interviews supported this information and demonstrated the influence their own motivation placed on their goals. Survey data were also obtained about the students' test scores and academic achievement. Data collected from the statistical and interview components of the study developed a greater understanding for the lack of Latinos in the sciences as influenced by personal and familial factors.

Improving Stochastic Communication Network Performance: Reliability vs. Throughput

DTIC Science & Technology

1991-12-01

increased to one. 2) arc survivabil.. ities will be increased in increments of one tenths. and 3) the costs to increase- arc si’rvivabilities were equal and...This reliability value is leni used to maximize the associated expected flow. For Net work A. a bIdget of (8)() pro(duces a tradcoff point at (.58.37...Network B for a buidgel of 2000 which allows a nel \\\\ork relial)ilitv of one to be achieved and a bidget of 1200 which allows for ;, maximum 57

JPRS Report, China, Red Flag, Number 5, 1 March 1988

DTIC Science & Technology

1988-05-20

film industry is that our productions fail to give a powerful driving force to the torrents of the time and reproduce the strong voice of the time...cadres and creative person- nel of our film industry must have the basic concept that in this great era of ours, films cannot do without a main...high tide in the film industry depend on this kind of "major productions." We may say that only when there has emerged a large number of outstanding

Individual Differences and Time-Sharing Ability: A Critical Review and Analysis.

DTIC Science & Technology

1982-03-01

number of subjects and variables will be discussed in section 2 ), no infallible specification method is available for use. However, a number of...82 P L ACKERMAN, W SCHNEIDER, C D WICKENS N00014-81-K-0034 UNCLASSIFIED HARL-ONRAO02 N I EENOMOE N 1.0 25 ~ 2 11111 _______11112.0~ MIRC f’ R NE,()L(31...GOVT ACCESSION NO. 3. RECIPIENT’S CATALOG NUMBER 8102 _ - 2 4. TITLE (end Subtitle) 5. TYPE OF REPORT & PERIOD COVERED Iudividual Differences and Time

Efficient Simulation and Novel Modeling by Using Generic Three-Dimensional Exact Solutions to Analyze Transport Dynamics in Turbulent Vortices

DTIC Science & Technology

2009-02-28

algorithm 16. SECURITY CLASSIFICATION OF: a. REPORT C b. ABSTRACT (’ c . THIS PAGE C 17. LIMITATION OF ABSTRACT SAR 18. NUMBER OF PAGES 16...further improved by in- cluding Fi^Fs ... obtained by very fast predictor - corrector scheme along / direction. 2 n/(El) 4 Fig. 1: Preliminary...by solving eq.l 1 with Euler predictor - corrector method. As a result, Uj can be evaluated from the expansion eq.9. • Step 2:- The normal

ASV3 dial-in interface recommendation for the Repository Based Software Engineering (RBSE) program

NASA Technical Reports Server (NTRS)

1992-01-01

The purpose of this report is to provide insight into the approach and design of the Cooperative User Interface (CUI). The CUI is being developed based on Hypercard technology and will provide the same look and feel as is provided by the NASA Electronic Library System (NELS) X-Window interface. The interaction between the user and ASCII-LIB is presented as well as the set of Hypercard Cards with which the user will work.

Research Plan for the Investigation of Cultural Resources in the Area of the Proposed Violet Site Alternative. New Lock and Connecting Channels, St. Bernard Parish, Louisiana

DTIC Science & Technology

1989-03-01

41& 993 FINAL REPORT August 1990 MUSEUM OF GEOSCIENCE Louisiana State University ¶ Baton Rouge bpioe to~t pbUc nelI Prepared for U.S. Army Corps of... Rouge , Louisiana 70803 P.O. Box 60267 New Orleans, LA 70160-0267 S.. NAME OF FUNDING/SPONSORING 8b. OFFICE SYMBOL 9. PROCUREMENT INSTRUMENT IDENTIFICATION...University Baton Rouge , LA 70803 TABLE OF CONTENTS List of Figures ................................. 2 Abstract ..................................... 4

Investigation of Sand-Cement Grouts

DTIC Science & Technology

1960-09-01

I -IEN NO Isis Table 1 InvestiiatLon of Sand-Cement Crouts Data on Lhe Physical Properties of the inely Divided Mineral Admixt)res Blaine Specific...Itoi, tuicrlt.nel, Caiftrnia; fl1; aish, Illinois; ;1iaricito, California; Lo’ss, Yisniasi~pi; bentornitoe, Wy~caing. Physical drnta for the raateriais...increase i’: tne a.cunt of .anj th-?t coul be puiped. As the diatomite had a specific ,i’face about 1C tines that of the loe33, it would appear that this

Air Force Flight Feeding. Volume 1. Evaluation of Current System and Alternative Concepts

DTIC Science & Technology

1989-07-01

3. How does ’show time’ (the time between actual pickup of meals and aircraft departure), affect flight kitchen food processing ? 4. What is the...inflexible meal heating process offered through use of convection ovens to reheat the frozen meals. Through discussions with active duty person- nel it...Fruit Punch Iced Tea, Hot Tea Milk Coffee Water Diet, Decaffeinated Drinks % of Responses 39.9 38.3 28.5 23.3 23.0 21.5 13.3 5.0 -59

Attività fotometrica di Plutone nel 2005

NASA Astrophysics Data System (ADS)

Bianciardi, Giorgio

2006-06-01

This report describes unfiltered CCD differential photometry of Pluto performed between 1 August and 10 September 2005. Results show that in the present year Pluto is maintaining a high photometric activity, higher than expected (maximum brightness variations of 0.29±0.02 magnitudes) in relation to the rotational period. Pluto's appearance is now drastically changing owing to viewing geometry and the next collapse of its atmosphere onto the surface. Amateurs too should dedicate particular attention to the photometric evolution of the planet.

The nutritive value of condensed wheat distillers solubles for cattle.

PubMed

De Boever, J L; Blok, M C; Millet, S; Vanacker, J; De Campeneere, S

2016-12-01

The chemical composition and the energy and protein value of five batches of condensed distillers solubles (CDS) originating from wheat were determined. The net energy for lactation (NEL) was derived from digestion coefficients obtained with sheep. The true protein digested in the small intestine (DVE) and the rumen degradable protein balance (OEB) were based on the rumen degradation rate (kd D ), the rumen undegradable fraction (U) and intestinal digestibility of undegraded protein (%DVBE) predicted by regression equations derived from a data set of 28 protein feeds with kd D , U and %DVBE determined in situ. The CDS is a by-product with a high, but very variable CP content (238 to 495 g/kg DM). The CP contained on average 81% amino acids, with glutamine as main component (on average 21.8% of CP) and a relatively good lysine proportion (3.0%). Further, CDS contains quite a lot of crude fat (mean±SD: 71±14 g/kg DM), glycerol (95±52 g/kg DM) and sugars (123±24 g/kg DM) resulting in a high organic matter digestibility (88.6±3.0%) and high NEL content (8.3±0.4 MJ/kg DM). The protein value showed a large variation, with DVE ranging from 122 to 244 g/kg DM and OEB from 50 to 204 g/kg DM. Wheat CDS is a rich source of minerals and trace elements with exception of calcium.

Prepartum nutrient intake alters palmitate metabolism by liver slices from peripartal dairy cows.

PubMed

Litherland, N B; Dann, H M; Drackley, J K

2011-04-01

We determined the effects of day relative to parturition and prepartum plane of nutrition on hepatic partitioning of palmitate metabolism to CO2, acid-soluble products (ASP), and esterified products (EP). Multiparous Holsteins (n=74) were fed different amounts of nutrients during the dry period in a 3 (far-off period diet)×2 (close-up period diet) factorial arrangement. During the far-off period (d -60 to -25) cows received a low-energy control diet fed ad libitum (100NRC) to meet National Research Council (NRC) requirements, a moderate-energy diet fed ad libitum to exceed NRC recommendations for net energy of lactation (NEL) by >50% (150NRC), or the same diet fed at restricted intake to provide 80% of NEL requirements (80NRC). During the close-up period (d -24 until parturition), cows were fed a diet for ad libitum intake to meet NRC recommendations or in restricted amounts to provide 80% of calculated NEL requirements. After parturition, all cows had ad libitum access to a lactation diet. Liver slices from biopsies on d -30, -14, 1, 14, and 28 relative to parturition were used to determine conversion of [1-(14)C] palmitate to CO2, ASP, and EP. Across diets, oxidation of palmitate to CO2 was decreased postpartum, whereas oxidation to ASP was increased at d 1 postpartum compared with other times. Conversion of palmitate to EP increased markedly postpartum, with the greatest rates at d 1 postpartum. Conversion of palmitate to CO2 and ASP on d 1 postpartum was lower and the proportion of palmitate metabolism as EP was greater for cows fed 150NRC than for those fed 100NRC or 80NRC. Hepatic triacylglycerol concentration at d 1 postpartum was greatest for cows fed 150NRC. Palmitate metabolism did not differ between close-up diets. Hepatic triacylglycerol was negatively correlated with tissue metabolism of palmitate to CO2 and ASP but positively correlated with metabolism to EP. Hepatic triacylglycerol was highly correlated with NEFA concentrations on the day of calving and d 1 postpartum but not with NEFA prepartum. In contrast, plasma BHBA postpartum was not correlated with hepatic palmitate metabolism by liver slices but was highly correlated with NEFA concentration prepartum. Excessive energy intake during the far-off dry period decreased hepatic palmitate oxidation and shifted palmitate metabolism toward greater esterification, consistent with greater hepatic triacylglycerol accumulation postpartum. Copyright © 2011 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Nutritional value of raw soybeans, extruded soybeans, roasted soybeans and tallow as fat sources in early lactating dairy cows.

PubMed

Amanlou, H; Maheri-Sis, N; Bassiri, S; Mirza-Aghazadeh, A; Salamatdust, R; Moosavi, A; Karimi, V

2012-01-01

Thirty multiparous Holstein cows (29.8 ± 4.01days in milk; 671.6 ± 31.47 kg of body weight) were used in a completely randomized design to compare nutritional value of four fat sources including tallow, raw soybeans, extruded soybeans and roasted soybeans for 8 weeks. Experimental diets were a control containing 27.4 % alfalfa silage, 22.5% corn silage, and 50.1% concentrate, and four diets with either tallow, raw soybean, extruded soybean, or roasted soybean added to provide 1.93% supplemental fat. Dry matter and NEL intakes were similar among treatments, while cows fed fat diets had significantly (P<0.05) high NEL intakes when compared to control with no fat. Supplemental fat, whether tallow or full fat soybeans increased milk production (1.89-2.45 kg/d; P<0.01) and FCM production (1.05-2.79; P<0.01). Milk fat yield and percentage of cows fed fat-supplemented diets were significantly (P<0.01 and P<0.05 respectively) higher than control. Between fat-supplemented diets, roasted soybean caused highest milk fat yield and extruded soybean caused lowest milk fat yield. There was no significant effect of supplemental fat on the milk protein and lactose content and yield. Feed efficiency of fat-supplemented diets was significantly (P<0.01) higher than control. Body weight, body weight change and BCS (body condition score) of cows, as well as energy balance and energy efficiency were similar between treatments. In conclusion, while there was no significant effect of fat sources on production response of cows, fat originating from heat-treated soybean help to minimize imported RUP (rumen undegradable protein) sources level as fish meal in comparison with tallow and raw soybean oil. In the Current study, there was no statistical significance among nutritional values of oil from extruded soybeans and roasted soybeans.

Cost-Benefit Analysis of a Bridge to Integrate the Management of Technical Information for Producing Technical Manuals and Training Courses

DTIC Science & Technology

2010-11-01

Philadelphia, and all Computer-Based Training (CBT) courses delivered by Navy eLearning (NeL), a part of the Naval Education and Training Command (NETC...concentrated exclu- sively on the benefit side—whether the Bridge would save money in producing future technical manuals and training courses. It...of $78.1 million in 10-year costs: a savings of $86.8 million in producing future HM&E manuals and NeL-delivered courses less $8.7 million in

Hydrodynamic Interactions during Launch and Recovery of a Small Boat from a Ship in a Seaway

DTIC Science & Technology

2014-11-28

during launch and recovery. The RHIB is based on a Zodiac H935, with properties given in Table 1 when loaded with 12 person- nel. Figure 1 shows the hull...and recovery of a small craft from a larger ship, wave-induced motions of the larger ship will influence dy- namic loads on the crane. The motions of... the small craft will be a major determinant of the safety of onboard personnel. This paper exam- ines wave-induced motions during launch and recovery

Excimer Laser Research.

DTIC Science & Technology

1975-08-01

and sample cylinder were repeatedly allowed to outgas at room temperature (under vacuum but valved off) and then cooled with liquid N_ snd pumped...i i I i | I I I I i I i i i | I I i i i i i l i | I l I I I 320 330 340 350 360 E7470 WAVELENGTH (nm) 2 2 Fig. 9 Densitometer Trace of XeF...2, Xs are within 10%. eFor Arl, Nel, NeBr, NeCl, and the helium halides the inert-gas ionization potential is so large that the Coulomb curve does

Digital, One Way, Acoustic Communication in the Ocean

DTIC Science & Technology

1990-09-01

compared with miliseconds) and that the chan- nel can be assumed to be very slowly time-varyingl. A different way to show the 3 rate of variation of...outputs of all the mark channels and all the space channels of the branch receivers and to compare them. Choosing the mark and the space at each branch...2 g -(T)A +A2"-fg()[ gT) g(ig (4.35) In the presense of specular multipath, the performance of the estimator is not only governed by the additve

An Airfield Too Far, the Army’s Search for a Runway

DTIC Science & Technology

1990-05-01

just to keep the war going. Pilots flew to the point of e>ý.austion--often nine to ten hours a day witho.t leaving their cockpits. If the British...ground controlled. approach radar (GCA) of post-World War II vintage, However, it does not have a radiation signature as a threat air defense radar. Using...AD-A241 034 zx.R WARL COLLEGE RESEARCH REPORT AN AIRFIELD TOO FAR, THE ARMY’S 5EARCH FOR A RUNWAY DTIC, LIEU.TENANT COLO-NEL KENT V. H~JFFORD, USA

Lightening Body Armor: Arroyo Support to the Army Response to Section 125 of the National Defense Authorization Act for Fiscal Year 2011

DTIC Science & Technology

2012-01-01

nel from fragmenting munitions, and the addition of SAPI will successfully defend against AK-47 ball ammunition. The ESAPI and XSAPI plates were...d ) Frequency of incidents of firefights 7.62 x 39mm ball Fragmenting munitions Threat X Threat Y Threat E Threat F Threat A Threat C Threat D...the threat in Afghani- stan today is primarily fragmenting munitions, 7.62mm x 39 ball bullets, and 7.62mm x 54R ball bullets. Current body armor

Mars astronomy: observations concerning Ares myth. (Italian Title: L'astronomia di Marte: osservazioni celate nel mito di Ares)

NASA Astrophysics Data System (ADS)

Colona, P.

2017-12-01

We show that the myth of Ares defeated by the giants Aloads is a description of how the planet Mars appears in the sky during its synodic revolution. This criptoscientific myth reported by Homer holds enough astronomical information to make sound this archaeoastronomical interpretation.The tale accounts for the length of the semiperiod of the Martian revolution and presents the notion that Mercury is the only planet which is always visible when Mars recovers after the solar conjunction.

77 FR 4407 - Modernization of Poultry Slaughter Inspection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-27

...The Food Safety and Inspection Service (FSIS) is proposing a new inspection system for young chicken and turkey slaughter establishments that would replace the current Streamlined Inspection System (SIS), the New Line Speed Inspection System (NELS), and the New Turkey Inspection System (NTIS). The Agency is also proposing several changes that would affect all establishments that slaughter poultry other than ratites, regardless of the inspection system under which they operate. This proposed rule is a result of the Agency's 2011 regulatory review efforts conducted under Executive Order 13563 on Improving Regulation and Regulatory Review.

Prevalence of Coronary Heart Disease Risk Factors in a Young Military Population

DTIC Science & Technology

1980-01-01

Junction Depression (>_ 1 mm) 1.9(4) 3.6(3) 2.4(7) nel. The most predominant factors found were obesity, Wolff - Parkinson White Syndrome 0.3(0) 0(0) 0.3...de- the outstanding technical assistance provided by Robert Mello, pression seen herein would appear to be relatively low Dan White . and Alice...Cooper, K. H., M. L, Pollock, R. P. Martin. S. R. White , 27. Mitchell, J. H., B. I. Sproule, and C. B. Chapman. 1958. A. C. Linnerud, and A. Jackson

The Martian Outflow Channels: Mgs Sheds New Light On Viking and Pathfinder Results

NASA Astrophysics Data System (ADS)

Lanz, J.; Jaumann, R.

The Mars Global Surveyor (MGS) Mission has, as most successful missions before, given stunningly new insights in the processes that shaped the Martian surface. But how do these findings and observations fit in the context of our pre-MGS knowledge? and do they fit at all? Combining data from the Viking, Pathfinder and MGS Missions, erosion processes in the circum-Chryse Region have been newly and extensively examined. Maximum discharge rates and flow velocities within the major outflow channels were calculated as well as sediment transport and sediment volumes eroded by the flows evaluating the erosion balance of the region. In a second step a detailed study of the available high resolution MOC-Images and lower resolution MOC and Viking context images was performed to evaluate the geologic and morphologic inventory of the outflow chan- nels. Focusing on morphologic and hydrologic differences to terrestrial outflow chan- nels as well as differences to earlier pre-MGS studies, theories and hypothesis con- cerning the outflow channels have been tested for their validity. New hydrologic cal- culations e.g. give different results than previously measured (e.g. Carr 1979, Robin- son &Tanaka 1990, Komatsu &Baker 1997). Maximum discharge rates are generally smaller (see also Williams et al. 2000), in some cases up to a factor of 2 to 3 (e.g. Ares Vallis), having a strong impact on the northern ocean theory. Some morphologic fea- tures that are typical for terrestrial flood features (such as inner channels, bar deposits, gravel dunes, etc) could not or not clearly be identified in any of the large outflow channels even in high resolution MOC-imagery. Younger resurfacing processes might have covered or obscured them. Others are hard to distinguish from non-fluvial, i.e. eo- lian, features from satellite images. Nevertheless, the overall absence of such features in the outflow channels is striking and shows again that processes on Mars differ sig- nificantly from those on Earth and similar features might well have different origins. A simple comparison of similarities only, will inevitably be misleading or incomplete.

[National epidemiological surveillance systems of mesothelioma cases].

PubMed

Ferrante, Pierpaolo; Binazzi, Alessandra; Branchi, Claudia; Marinaccio, Alessandro

2016-01-01

INTRODUZIONE: sebbene la relazione causale tra esposizione ad amianto e malattie neoplastiche sia ben nota, in molti Paesi il consumo del materiale è ancora rilevante e crescente. A causa della lunga latenza, nei Paesi dove è stato bandito (come in Italia) è oggi in corso un'epidemia di malattie correlate ad amianto. OBIETTIVI: descrivere i sistemi di sorveglianza dei mesoteliomi attivi nel mondo mediante un'analisi comparativa. è stata condotta una revisione bibliografica della letteratura disponibile sui sistemi di sorveglianza epidemiologica dei mesoteliomi attivi nel mondo, comparando metodi e risultati disponibili. RISULTATI: sistemi di ricerca dei casi incidenti e di analisi anamnestica dei soggetti ammalati sono attivi solo in Italia, Francia e Corea del Sud. I Paesi presso i quali sono attivi sistemi di rilevazione e controllo dei casi incidenti di mesotelioma sono quelli in cui vige il bando dell'amianto e che hanno sperimentato consumi rilevanti in passato. Non sono stati istituiti sistemi epidemiologici di sorveglianza in molti Paesi dove il consumo di amianto è ancora importante (inclusi Russia, Cina, India e Brasile). CONCLUSIONI: si conferma l'importanza dei sistemi di sorveglianza epidemiologica dei mesoteliomi per la sanità pubblica, il sostegno alle politiche di welfare e la prevenzione dei rischi. Lo sviluppo di progetti per tendere a una maggiore uniformità nei metodi di ricerca dei casi, di classificazione delle diagnosi e dell'esposizione e nelle tecniche di analisi dei dati potrebbe consentire una maggiore fruibilità dei dati aggregati. La disponibilità di dati internazionali confrontabili può essere di stimolo all'adozione di provvedimenti di bando internazionale.

Riferimenti, simboli e numerologia astronomica nel Canzoniere di Petrarca

NASA Astrophysics Data System (ADS)

Colona, Paolo

The astronomical knowledge of Petrarch and his use of astronomical references in the renowned Canzoniere are examined with a commented anthology of the most relevant astronomical verses in that work. We discuss the identification of the first two verses of the poetry "Solo et pensoso" as a precise description of the astrological type of Saturn. The repeated presence of an ancient astronomical symbol such as the division of the circle in 12 parts is highlighted. The coded presence in the Canzoniere of the most relevant astronomical numbers 7, 12 and 365 is also discovered and shown.

Gamma dosimetric parameters in some skeletal muscle relaxants

NASA Astrophysics Data System (ADS)

Manjunatha, H. C.

2017-09-01

We have studied the attenuation of gamma radiation of energy ranging from 84 keV to 1330 keV (^{170}Tm, ^{22}Na,^{137}Cs, and ^{60}Co) in some commonly used skeletal muscle relaxants such as tubocurarine chloride, gallamine triethiodide, pancuronium bromide, suxamethonium bromide and mephenesin. The mass attenuation coefficient is measured from the attenuation experiment. In the present work, we have also proposed the direct relation between mass attenuation coefficient (μ /ρ ) and mass energy absorption coefficient (μ _{en}/ρ ) based on the nonlinear fitting procedure. The gamma dosimetric parameters such as mass energy absorption coefficient (μ _{en}/ρ ), effective atomic number (Z_{eff}), effective electron density (N_{el}), specific γ-ray constant, air kerma strength and dose rate are evaluated from the measured mass attentuation coefficient. These measured gamma dosimetric parameters are compared with the theoretical values. The measured values agree with the theoretical values. The studied gamma dosimetric values for the relaxants are useful in medical physics and radiation medicine.

Dischi (E Jet) Nelle Stelle Massicce Giovani

NASA Astrophysics Data System (ADS)

Cesaroni, Riccardo

2017-11-01

In questo contributo verrà discussa l'importanza dei dischi e jet ad essi asso- ciati per la formazione delle stelle di tipo spettrale OB e verranno presentati i risultati recentemente ottenuti con ALMA in questo ambito. In particolare mostr- eremo che la struttura del disco sembra risentire della complessità dell'ambiente circostante e che la probabilità di rivelare un disco attorno alle stelle di più alta massa è massima in una fase evolutiva intermedia. Infine discuteremo la possibilità che il fenomeno di accrescimento dal disco sulla stella possa avvenire in maniera discontinua mediante "burst", probabilmente dovuti ad instabilità nel disco.

Academic Performance of Language-Minority Students and All-Day Kindergarten: A Longitudinal Study

ERIC Educational Resources Information Center

Chang, Mido

2012-01-01

This longitudinal study examined the effect of all-day kindergarten programs on the academic achievement of students from racial language minority and low socioeconomic class. The study employed a series of 3-level longitudinal multilevel analyses using a nationally representative database, the Early Childhood Longitudinal Study (ECLS). The study…

77 FR 39344 - Agency Information (Post-9/11 GI Bill Education Longitudinal Study Survey) Activity Under OMB Review

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-02

... DEPARTMENT OF VETERANS AFFAIRS [OMB Control No. 2900-New (Post-9/11 GI Bill Longitudinal Study Survey)] Agency Information (Post-9/11 GI Bill Education Longitudinal Study Survey) Activity Under OMB...-9/11 GI Bill Longitudinal Study Survey) in any correspondence For Further Information or a Copy of...

Tailored Panel Management: A Theory-Based Approach to Building and Maintaining Participant Commitment to a Longitudinal Study.

PubMed

Estrada, Mica; Woodcock, Anna; Schultz, P Wesley

2014-02-01

Many psychological processes unfold over time, necessitating longitudinal research designs. Longitudinal research poses a host of methodological challenges, foremost of which is participant attrition. Building on Dillman's work, we provide a review of how social influence and relationship research informs retention strategies in longitudinal studies. Objective: We introduce the tailored panel management (TPM) approach, which is designed to establish communal norms that increase commitment to a longitudinal study, and this commitment, in turn, increases response rates and buffers against attrition. Specifically, we discuss practices regarding compensation, communication, consistency, and credibility that increase longer term commitment to panel participation. Research design: Throughout the article, we describe how TPM is being used in a national longitudinal study of undergraduate minority science students. TheScienceStudy is a continuing panel, which has 12 waves of data collected across 6 academic years, with response rates ranging from 70% to 92%. Although more than 90% of participants have either left or graduated from their undergraduate degree program, this highly mobile group of people remains engaged in the study. TheScienceStudy has usable longitudinal data from 96% of the original panel. Conclusion: This article combines social psychological theory, current best practice, and a detailed case study to illustrate the TPM approach to longitudinal data collection. The approach provides guidance for other longitudinal researchers, and advocates for empirical research into longitudinal research methodologies. © The Author(s) 2014.

Anti-NGF Local Therapy for Autonomic Dysreflexia in Spinal Cord Injury

DTIC Science & Technology

2014-12-01

Liposome + NGF antisense OND 20cmH2O 40cmH2O 60cmH2O 20cmH2O 40cmH2O 60cmH2O 160 280 160 280 Ar te ria l b lo od p re ss ur e (m m Hg ) A B C D 9 V...5,11 Opening of the sensory ion chan- nels can be enhanced or suppressed by a wide variety of uro thelial and inflammatory-cell-derived regulators...observed in transgenic mice that exhibit uro - thelial NGF overexpression.20 It is unknown whether the urothelium or mast cells are the primary source

VII Workshop Italiano sulla fisica pp a LHC

NASA Astrophysics Data System (ADS)

LHCpp2016 è la settima edizione dell'incontro nazionale sulla fisica p-p a LHC. Questa serie di incontri è nata a Pisa nel 2003 con lo scopo di stimolare lo scambio di idee tra le comunità sperimentali di ATLAS, CMS e LHCB e la comunità teorica. Caratteristica fondamentale di questi incontri è la preparazione di larga parte dei talk in collaborazione tra i vari esperimenti e la comunità teorica. Largo spazio nella preparazione e presentazione dei talk viene dato ai giovani ricercatori. In questa settima edizione, che si tiene di nuovo a Pisa, vogliamo concentrare l'attenzione sulle potenzialità di scoperta offerte dai dati raccolti durante il runII di LHC.

An intercomparison of NEL and DHL water flow facilities using a twin orifice plate flowmeter assembly

NASA Technical Reports Server (NTRS)

Dejong, J.; Spencer, E. A.

1983-01-01

A 205 mm transfer standard orifice plate meter assembly, consisting of two orifice plates in series separated by a length of pipe containing a flow straightener, was calibrated in two water flow facilities. Results show that the agreement in the characteristics of such a differential pressure transfer standard package is within 0.17% over a 10:1 range from flow rates of approximately 8 to 80 l/sec. When the range over which the comparison was made was limited to that for which the calibration graphs gave straight lines, the agreement is 0.1% in 3 of the 4 calibrations (0.17% in the fourth).

Trajectories of Mental Health over 16 Years amongst Young Adult Women: The Australian Longitudinal Study on Women's Health

ERIC Educational Resources Information Center

Holden, Libby; Ware, Robert S.; Lee, Christina

2016-01-01

This article used data from 5,171 young women participating in the Australian Longitudinal Study on Women's Health, a nationally representative longitudinal cohort study, to identify longitudinal trajectory patterns of mental health across 6 surveys over 16 years of early adulthood, from age 18-23 to age 34-39. In addition, we identified both…

A Longitudinal Examination of Childhood Maltreatment and Adolescent Obesity: Results from the National Longitudinal Study of Adolescent Health (AddHealth) Study

ERIC Educational Resources Information Center

Shin, Sunny Hyucksun; Miller, Daniel P.

2012-01-01

Objectives: We sought to explore the association between childhood maltreatment (e.g., neglect, physical and sexual abuse) and longitudinal growth trajectories of body mass index (BMI) from adolescence to young adulthood. Methods: We used latent curve modeling to examine data from the National Longitudinal Study of Adolescent Health (N = 8,471),…

Coping with Memory Effect and Serial Correlation when Estimating Reliability in a Longitudinal Framework

ERIC Educational Resources Information Center

Laenen, Annouschka; Alonso, Ariel; Molenberghs, Geert; Vangeneugden, Tony; Mallinckrodt, Craig H.

2010-01-01

Longitudinal studies are permeating clinical trials in psychiatry. Therefore, it is of utmost importance to study the psychometric properties of rating scales, frequently used in these trials, within a longitudinal framework. However, intrasubject serial correlation and memory effects are problematic issues often encountered in longitudinal data.…

[Evaluation of mercury exposure in populations living near the industrial Augusta Bay (Sicily Region, Southern Italy)].

PubMed

Bonsignore, Maria; Andolfi, Nunzia; Quinci, Enza Maria; Madeddu, Anselmo; Tisano, Francesco; Ingallinella, Vincenzo; Castorina, Maria; Sprovieri, Mario

2016-01-01

OBIETTIVI: valutare e quantificare l'esposizione umana al mercurio (Hg) ed esplorare i fattori chiave che influenzano la contaminazione nelle popolazioni residenti in prossimità della Rada di Augusta, un'area a elevato rischio ambientale a causa degli effetti degli sversamenti incontrollati di Hg da parte di uno dei più grandi impianti cloro-soda d'Europa. DISEGNO: un campione di residenti nei comuni di Augusta, Priolo e Melilli (Sicilia orientale) è stato selezionato per lo studio di biomonitoraggio umano. Un questionario dettagliato è stato somministrato a ogni partecipante per raccogliere informazioni anagrafiche sulle abitudini di vita e alimentari. I livelli di Hg in sangue e capelli, usati come traccianti di esposizione a metilmercurio, sono stati messi in relazione al consumo di pesce locale. Il contenuto di Hg nelle urine è stato utilizzato per esplorare eventuali esposizioni atmosferiche a Hg inorganico. Una regressione lineare multivariata è stata applicata con l'obiettivo di esplorare i fattori che influenzano l'esposizione umana al Hg. L'approccio tossicocinetico è stato impiegato al fine di calcolare la dose settimanale provvisoria tollerabile ( provisional tolerable weekly intake, PTWI) e di predire le concentrazioni di Hg attese nel sangue degli individui con una dieta alimentare basata esclusivamente su pesce locale. 224 individui residenti nei comuni di Augusta, Melilli e Priolo. RISULTATI: eccessi di Hg sono stati misurati nel sangue e nei capelli del campione considerato. I più alti livelli sono stati rilevati ad Augusta, dove anche il consumo di pesce locale risulta maggiore. I valori di dose settimanale tollerabile provvisoria (PTWI) calcolati eccedono, nella maggior parte dei casi, le raccomandazioni internazionali, specialmente nei residenti ad Augusta. CONCLUSIONI: gli elevati livelli di Hg registrati nei campioni di sangue e capelli derivano, con ogni probabilità, dal consumo di pesce locale. Rispetto ad Augusta, gli individui di Priolo e Melilli subiscono un impatto più limitato. L'esposizione a Hg inorganico può essere considerata trascurabile.

Use of missing data methods in longitudinal studies: the persistence of bad practices in developmental psychology.

PubMed

Jelicić, Helena; Phelps, Erin; Lerner, Richard M

2009-07-01

Developmental science rests on describing, explaining, and optimizing intraindividual changes and, hence, empirically requires longitudinal research. Problems of missing data arise in most longitudinal studies, thus creating challenges for interpreting the substance and structure of intraindividual change. Using a sample of reports of longitudinal studies obtained from three flagship developmental journals-Child Development, Developmental Psychology, and Journal of Research on Adolescence-we examined the number of longitudinal studies reporting missing data and the missing data techniques used. Of the 100 longitudinal studies sampled, 57 either reported having missing data or had discrepancies in sample sizes reported for different analyses. The majority of these studies (82%) used missing data techniques that are statistically problematic (either listwise deletion or pairwise deletion) and not among the methods recommended by statisticians (i.e., the direct maximum likelihood method and the multiple imputation method). Implications of these results for developmental theory and application, and the need for understanding the consequences of using statistically inappropriate missing data techniques with actual longitudinal data sets, are discussed.

Feeding a higher forage diet prepartum decreases incidences of subclinical ketosis in transition dairy cows.

PubMed

Vickers, L A; Weary, D M; Veira, D M; von Keyserlingk, M A G

2013-02-01

A common feeding practice during the dry period is to switch dairy cows to an energy-dense diet 3 wk prepartum, but this practice may lead to the overconsumption of energy and increase the risk of metabolic disease postpartum. The aim of this trial was to compare the metabolic status of transition Holstein dairy cows fed a 77% forage diet (77F; NEl = 1.46 Mcal/kg; NDF = 41%) vs. those fed an 87% forage diet (87F; NEl = 1.41 Mcal/kg; 48% NDF). Approximately 60 d before calving, cows were dried off, housed in a free stall barn, and fed the 87F diet. Three weeks before expected calving, cows were randomly assigned to either the 77F treatment and switched to this diet (n = 45) or assigned to the 87F treatment and stayed on the dry cow ration until parturition (n = 42). After parturition, all cows were fed a common lactation diet (NEl = 1.59 Mcal/kg; 36% NDF). Dry matter intake was measured daily from 2 wk before to 2 wk after calving. Blood was sampled daily for 10 d postpartum. Subclinical ketosis was diagnosed using a threshold of β-hydroxybutyrate (BHBA) ≥ 1.0 mmol/L after calving. The percentage of cows pregnant and odds of being pregnant for each treatment group were determined at 60, 90, and 120 d in milk through ultrasound by the herd veterinarian. Cows on the 87F diet consumed less DM prepartum than those on the 77F diet (12.7 ± 0.3 kg/d vs. 15.4 ± 0.3 kg/d, P < 0.001), but no difference in DMI was detected after calving (19.7 ± 5.5 kg/d; P = 0.87). Although the calculated prepartum required energy intake was the same for the 2 treatments (15.3 ± 1.2 Mcal/d; P = 0.16), cows on the 77F diet consumed 4.5 Mcal/d more than those on the 87F diet (22.5 ± 0.5 Mcal/d vs. 18.0 ± 0.5 Mcal/d; P < 0.001). Postpartum concentration of BHBA was less for cows fed the 87F diet prepartum (0.49 ± 0.02 mmol/L vs. 0.59 ± 0.02 mmol/L; P = 0.02), and fewer animals on this diet were diagnosed subclinical ketosis (SCK; 49% vs. 17%; P = 0.001). Milk production tended to be less for cows fed the 87F diet prepartum (47.3 ± 0.4 kg/d vs. 48.8 ± 0.4 kg/d; P = 0.10) for the first 22 wk of lactation, which was significant for d 7 to 28 of lactation (44.6 ± 1.1 kg/d vs. 47.6 ± 1.0 kg/d; P = 0.05). Although sample size was small to draw strong conclusions on reproductive performance, at 120 d in milk, cows on the 87F diet were 0.3 times more likely to be pregnant (P = 0.03). These results indicate that feeding an 87F diet before calving can reduce rates of SCK in transition dairy cows.

In vivo and in vitro effects of the herbicide Roundup(®) on developmental stages of the trematode Echinostoma paraensei.

PubMed

Monte, Tainá C de C; Garcia, Juberlan; Gentile, Rosana; de Vasconcellos, Maurício Carvalho; Souza, Joyce; Braga, Brunna V; Maldonado, Arnaldo

2016-10-01

The exposure of wildlife and humans to toxic residues of Roundup(®) through agricultural practices or the food chain has been reported since the herbicide was found contaminating rivers. Glyphosate, N-(phosphonomethyl)glycine acid, is a nonselective post-emergent herbicide and is formulated as an isopropylamine salt with the surfactant taloamine polyethoxylate (POEA) representing the commercial formulation of Roundup(®). There is little knowledge about the effects of the herbicide on helminth parasites, particularly those whose life cycle is related to water bodies. Here we investigated the effects of the Roundup(®) on the food-borne trematode Echinostoma paraensei in experimental conditions using different developmental stages (eggs, miracidia, cercariae, metacercariae, newly excysted larvae (NEL), helminths at seven days and helminths at fourteen days). Three different herbicide concentrations were tested based on concentrations typically applied in the field: 225, 450 and 900 mg/L. Specimens were analyzed in vitro for hatching miracidia, mortality and excystment rate of metacercariae and in vivo for parasitic load and egg production. There was a significant difference in the hatching miracidia rate only for the newly embryonated eggs. The mortality of specimens and excystment rate of metacercariae were concentration-dependent. There was a significant difference in the miracidia mortality with respect to concentration until 56.3 mg/L. The same effect was observed for cercariae, and mortality was observed from 15 min onwards at concentrations of 225-900 mg/L. At low concentrations, mortality was detected after 30 min. The effects of the herbicide concentration on NEL and on helminths at seven and fourteen days showed a significant difference after 24 h. There was no significant difference in parasitic load and egg production after infection of rodents with exposed metacercariae. All developmental stages of the trematode E. paraensei were affected by Roundup(®) exposure under experimental conditions. These results suggest that dynamics of transmission of the trematode could be affected in the natural environments. The study also reinforces the usefulness of this trematode as a good model organism to test pesticides regarding human and environmental health. Copyright © 2016 Elsevier Inc. All rights reserved.

Effects of prepartal body condition score and peripartal energy supply of dairy cows on postpartal lipolysis, energy balance and ketogenesis: an animal model to investigate subclinical ketosis.

PubMed

Schulz, Kirsten; Frahm, Jana; Meyer, Ulrich; Kersten, Susanne; Reiche, Dania; Rehage, Jürgen; Dänicke, Sven

2014-08-01

Subclinical ketosis is a metabolic disorder which often goes undiagnosed and leads to constricted performance and an impairment of general condition. In the current study subclinical ketosis was characterised by a β-hydroxybutyrate (BHB) concentration of >1·2 mmol/l in blood serum. To generate this metabolic situation, an animal model was created. The model, based on group-specific interaction of dietary energy supply and body condition, is appropriate for testing the medical effectiveness of treating this kind of ketosis and its concomitants. During the trial, 18 dairy cows (primiparous and pluriparous) were assigned, according to their body condition score (BCS) 6 weeks before expected parturition, to a normal [6.78 MJ net energy for lactation (NEL)/kg dry matter; 20% concentrate] or to a high-energy feeding group (7·71 MJ NEL/kg dry matter; 60% concentrate). Therefore cows with the highest BCS were allocated to the high-energy group to enhance the contrast with the control group. Statistical analysis was done using the MIXED procedure of SAS. Effects were declared significant when P-values were ⩽0.05. Owing to the higher energy concentration and dry matter intake, the energy intake and balance was significantly higher in the high-energy feeding group, with strong effects on lipid metabolism and health in blood and liver post partum. Within the first 2 weeks after calving, 8 out of 9 cows (89%) of the high-energy group had BHB values indicative of subclinical ketosis. These cows also had significantly higher values of non-esterified fatty acids (NEFA), aspartate transaminase (AST) and glutamate dehydrogenase (GLDH) post partum, as well as a raised total lipid content of the liver. RQUICKI, a calculated parameter which is based on serum concentrations of glucose, insulin and NEFA to assess the insulin sensitivity, was not affected by treatment. Therefore, RQUICKI does not seem to be the right parameter for diagnosing decreased insulin sensitivity in cows affected by subclinical ketosis. The milk fat and the fat:protein ratio of the high-energy group was also higher, even though there was no decrease in milk yield for cows with subclinical BHB values.

Human Perivascular Stem Cells Show Enhanced Osteogenesis and Vasculogenesis with Nel-Like Molecule I Protein

PubMed Central

Askarinam, Asal; James, Aaron W.; Zara, Janette N.; Goyal, Raghav; Corselli, Mirko; Pan, Angel; Liang, Pei; Chang, Le; Rackohn, Todd; Stoker, David; Zhang, Xinli; Ting, Kang; Péault, Bruno

2013-01-01

An ideal mesenchymal stem cell (MSC) source for bone tissue engineering has yet to be identified. Such an MSC population would be easily harvested in abundance, with minimal morbidity and with high purity. Our laboratories have identified perivascular stem cells (PSCs) as a candidate cell source. PSCs are readily isolatable through fluorescent-activated cell sorting from adipose tissue and have been previously shown to be indistinguishable from MSCs in the phenotype and differentiation potential. PSCs consist of two distinct cell populations: (1) pericytes (CD146+, CD34−, and CD45−), which surround capillaries and microvessels, and (2) adventitial cells (CD146−, CD34+, and CD45−), found within the tunica adventitia of large arteries and veins. We previously demonstrated the osteogenic potential of pericytes by examining pericytes derived from the human fetal pancreas, and illustrated their in vivo trophic and angiogenic effects. In the present study, we used an intramuscular ectopic bone model to develop the translational potential of our original findings using PSCs (as a combination of pericytes and adventitial cells) from human white adipose tissue. We evaluated human PSC (hPSC)-mediated bone formation and vascularization in vivo. We also examined the effects of hPSCs when combined with the novel craniosynostosis-associated protein, Nel-like molecule I (NELL-1). Implants consisting of the demineralized bone matrix putty combined with NELL-1 (3 μg/μL), hPSC (2.5×105 cells), or hPSC+NELL-1, were inserted in the bicep femoris of SCID mice. Bone growth was evaluated using microcomputed tomography, histology, and immunohistochemistry over 4 weeks. Results demonstrated the osteogenic potential of hPSCs and the additive effect of hPSC+NELL-1 on bone formation and vasculogenesis. Comparable osteogenesis was observed with NELL-1 as compared to the more commonly used bone morphogenetic protein-2. Next, hPSCs induced greater implant vascularization than the unsorted stromal vascular fraction from patient-matched samples. Finally, we observed an additive effect on implant vascularization with hPSC+NELL-1 by histomorphometry and immunohistochemistry, accompanied by in vitro elaboration of vasculogenic growth factors. These findings hold significant implications for the cell/protein combination therapy hPSC+NELL-1 in the development of strategies for vascularized bone regeneration. PMID:23406369

Colorado Longitudinal Twin Study of Reading Disability

ERIC Educational Resources Information Center

Wadsworth, Sally J.; DeFries, John C.; Olson, Richard K.; Willcutt, Erik G.

2007-01-01

The primary objectives of the present study are to introduce the Colorado Longitudinal Twin Study of Reading Disability, the first longitudinal twin study in which subjects have been specifically selected for having a history of reading difficulties, and to present some initial assessments of the stability of reading performance and cognitive…

76 FR 65187 - Notice of Proposed Information Collection Requests

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-20

... careers. This study includes a new student assessment in algebraic skills, reasoning, and problem solving... School Longitudinal Study of 2009 (HSLS:09) High School Transcript Collection and College Update Field... Longitudinal Study of 2009 (HSLS:09) is a nationally representative, longitudinal study of more than 20,000...

A vector-product information retrieval system adapted to heterogeneous, distributed computing environments

NASA Technical Reports Server (NTRS)

Rorvig, Mark E.

1991-01-01

Vector-product information retrieval (IR) systems produce retrieval results superior to all other searching methods but presently have no commercial implementations beyond the personal computer environment. The NASA Electronic Library Systems (NELS) provides a ranked list of the most likely relevant objects in collections in response to a natural language query. Additionally, the system is constructed using standards and tools (Unix, X-Windows, Notif, and TCP/IP) that permit its operation in organizations that possess many different hosts, workstations, and platforms. There are no known commercial equivalents to this product at this time. The product has applications in all corporate management environments, particularly those that are information intensive, such as finance, manufacturing, biotechnology, and research and development.

Effetto black drop e istanti dei contatti nel transito di Venere sul Sole

NASA Astrophysics Data System (ADS)

di Giovanni, Giovanni

2005-04-01

Digital measurements of the chords common to the Sun and Venus during the transit of 8 June 2004 are reported. The time of the four contacts of the planet with the solar limb are calculated resolving the relative equations for entry and exit phases. The solutions were obtained with least square methods applied to experimental data with analytical functions used by different Authors during the Sun's eclipses. The well-known black drop effect was observed during the third contact. Atmospheric turbulence and optical effects interfere making timings uncertain by at least one second. There is also a comment about the numerical values and the estimate of the experimental errors. The observations were made by four high school students.

A Longitudinal Study of Adolescent Adjustment Following Family Transitions

ERIC Educational Resources Information Center

Ruschena, Eda; Prior, Margot; Sanson, Ann; Smart, Diana

2005-01-01

Background: This study examined the impact of family transitions, that is, parental separation, divorce, remarriage and death, upon the lives of Australian children and adolescents in a longitudinal study of temperament and development. Methods: Using longitudinal and concurrent questionnaire data, outcomes for young people experiencing…

77 FR 51788 - Notice of Submission for OMB Review; Institute of Education Sciences; Education Longitudinal...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-27

...; Education Longitudinal Study 2002 (ELS:2002) Third Follow-Up Postsecondary Transcripts (ELS:2002 PETS) and Financial Aid Feasibility Study (ELS:2002 FAFS) SUMMARY: The Education Longitudinal Study of 2002 (ELS:2002) is a nationally representative study of two high school grade cohorts (spring 2002 tenth-graders and...

The Impact of Mixing Modes on Reliability in Longitudinal Studies

ERIC Educational Resources Information Center

Cernat, Alexandru

2015-01-01

Mixed-mode designs are increasingly important in surveys, and large longitudinal studies are progressively moving to or considering such a design. In this context, our knowledge regarding the impact of mixing modes on data quality indicators in longitudinal studies is sparse. This study tries to ameliorate this situation by taking advantage of a…

Integrating Prospective Longitudinal Data: Modeling Personality and Health in the Terman Life Cycle and Hawaii Longitudinal Studies

ERIC Educational Resources Information Center

Kern, Margaret L.; Hampson, Sarah E.; Goldberg, Lewis R.; Friedman, Howard S.

2014-01-01

The present study used a collaborative framework to integrate 2 long-term prospective studies: the Terman Life Cycle Study and the Hawaii Personality and Health Longitudinal Study. Within a 5-factor personality-trait framework, teacher assessments of child personality were rationally and empirically aligned to establish similar factor structures…

77 FR 2349 - Proposed Information Collection (Vocational Rehabilitation and Employment Longitudinal Study...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-17

... DEPARTMENT OF VETERANS AFFAIRS [OMB Control No. 2900-New (VR&E Longitudinal Study Survey... Rehabilitation and Employment (VR&E) Program. DATES: Written comments and recommendations on the proposed [[Page... . Please refer to ``OMB Control No. 2900--New (VR&E Longitudinal Study Survey)'' in any correspondence...

Beyond Terman: Contemporary Longitudinal Studies of Giftedness and Talent.

ERIC Educational Resources Information Center

Subotnik, Rena F., Ed.; Arnold, Karen D., Ed.

This volume presents 16 papers describing recent longitudinal studies of giftedness. Papers have the following titles and authors: (1) "Longitudinal Study of Giftedness and Talent" (Rena F. Subotnik and Karen D. Arnold); (2) "The Illinois Valedictorian Project: Early Adult Careers of Academically Talented Male High School Students" (Karen D.…

Peer Victimization in Childhood and Internalizing Problems in Adolescence: A Prospective Longitudinal Study

ERIC Educational Resources Information Center

Zwierzynska, Karolina; Wolke, Dieter; Lereya, Tanya S.

2013-01-01

Traumatic childhood experiences have been found to predict later internalizing problems. This prospective longitudinal study investigated whether repeated and intentional harm doing by peers (peer victimization) in childhood predicts internalizing symptoms in early adolescence. 3,692 children from the Avon Longitudinal Study of Parents and…

Studying the Longitudinal Study. I. Introduction: Do Impromptu Essays Show Changes in Critical Thinking over the Span of College? Cautions and Insights from a Pilot Case Study.

ERIC Educational Resources Information Center

Clark, Francelia

The problematic results of longitudinal studies on college writing indicate the need for multidimensional studies to be able to explore perceptible changes in students' writing. Accordingly a small pilot case study, to explore the promise and the limitations of doing a longitudinal multidimensional study, investigated whether impromptu essays…

Longitudinal Changes in Access to Health Care by Immigrant Status among Older Adults: The Importance of Health Insurance as a Mediator

ERIC Educational Resources Information Center

Choi, Sunha

2011-01-01

Purpose: This longitudinal study examined the role of health insurance in access to health care among older immigrants. Design and Methods: Using data from the Second Longitudinal Study of Aging, the longitudinal trajectories of having a usual source of care were compared between 3 groups (all 70+ years): (a) late-life immigrants with less than 15…

Stress Process of Illicit Drug Use among U.S. Immigrants' Adolescent Children: A Longitudinal Study

ERIC Educational Resources Information Center

Choo, Hyekyung

2012-01-01

This study examined a full path model of stress process for predicting illicit drug use among Asian and Latino immigrants' adolescent children. Using 2-year longitudinal data (National Longitudinal Study of Adolescent Health) from a sample of adolescents with Asian or Latino immigrant parents (N = 2,353), the study explored structural…

Investigation of 2‐stage meta‐analysis methods for joint longitudinal and time‐to‐event data through simulation and real data application

PubMed Central

Tudur Smith, Catrin; Gueyffier, François; Kolamunnage‐Dona, Ruwanthi

2017-01-01

Background Joint modelling of longitudinal and time‐to‐event data is often preferred over separate longitudinal or time‐to‐event analyses as it can account for study dropout, error in longitudinally measured covariates, and correlation between longitudinal and time‐to‐event outcomes. The joint modelling literature focuses mainly on the analysis of single studies with no methods currently available for the meta‐analysis of joint model estimates from multiple studies. Methods We propose a 2‐stage method for meta‐analysis of joint model estimates. These methods are applied to the INDANA dataset to combine joint model estimates of systolic blood pressure with time to death, time to myocardial infarction, and time to stroke. Results are compared to meta‐analyses of separate longitudinal or time‐to‐event models. A simulation study is conducted to contrast separate versus joint analyses over a range of scenarios. Results Using the real dataset, similar results were obtained by using the separate and joint analyses. However, the simulation study indicated a benefit of use of joint rather than separate methods in a meta‐analytic setting where association exists between the longitudinal and time‐to‐event outcomes. Conclusions Where evidence of association between longitudinal and time‐to‐event outcomes exists, results from joint models over standalone analyses should be pooled in 2‐stage meta‐analyses. PMID:29250814

Future consequences of decreasing marginal production efficiency in the high-yielding dairy cow.

PubMed

Moallem, U

2016-04-01

The objectives were to examine the gross and marginal production efficiencies in high-yielding dairy cows and the future consequences on dairy industry profitability. Data from 2 experiments were used in across-treatments analysis (n=82 mid-lactation multiparous Israeli-Holstein dairy cows). Milk yields, body weights (BW), and dry matter intakes (DMI) were recorded daily. In both experiments, cows were fed a diet containing 16.5 to 16.6% crude protein and net energy for lactation (NEL) at 1.61 Mcal/kg of dry matter (DM). The means of milk yield, BW, DMI, NEL intake, and energy required for maintenance were calculated individually over the whole study, and used to calculate gross and marginal efficiencies. Data were analyzed in 2 ways: (1) simple correlation between variables; and (2) cows were divided into 3 subgroups, designated low, moderate, and high DMI (LDMI, MDMI, and HDMI), according to actual DMI per day: ≤ 26 kg (n=27); >26 through 28.2 kg (n=28); and >28.2 kg (n=27). The phenotypic Pearson correlations among variables were analyzed, and the GLM procedure was used to test differences between subgroups. The relationships between milk and fat-corrected milk yields and the corresponding gross efficiencies were positive, whereas BW and gross production efficiency were negatively correlated. The marginal production efficiency from DM and energy consumed decreased with increasing DMI. The difference between BW gain as predicted by the National Research Council model (2001) and the present measurements increased with increasing DMI (r=0.68). The average calculated energy balances were 1.38, 2.28, and 4.20 Mcal/d (standard error of the mean=0.64) in the LDMI, MDMI, and HDMI groups, respectively. The marginal efficiency for milk yields from DMI or energy consumed was highest in LDMI, intermediate in MDMI, and lowest in HDMI. The predicted BW gains for the whole study period were 22.9, 37.9, and 75.8 kg for the LDMI, MDMI, and HDMI groups, respectively. The present study demonstrated that marginal production efficiency decreased with increasing feed intake. Because of the close association between production and intake, the principle of diminishing marginal productivity may explain why increasing milk production (and consequently increasing intake) does not always enhance profitability. To maintain high production efficiency in the future, more attention should be given to optimizing rather than maximizing feed intake, a goal that could be achieved by nutritional manipulations that would increase digestibility or by using a diet of denser nutrients that would provide all nutritional requirements from lower intake. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

77 FR 20885 - Agency Information Collection (Vocational Rehabilitation and Employment Longitudinal Study Survey...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-06

... DEPARTMENT OF VETERANS AFFAIRS [OMB Control No. 2900-New (VR&E Longitudinal Study Survey)] Agency... Building, Room 10235, Washington, DC 20503 (202) 395-7316. Please refer to ``OMB Control No. 2900-New (VR&E....gov . Please refer to ``OMB Control No. 2900-New (VR&E Longitudinal Study Survey)''. SUPPLEMENTARY...

The Timing of Maternal Depressive Symptoms and Child Cognitive Development: A Longitudinal Study

ERIC Educational Resources Information Center

Evans, Jonathan; Melotti, Roberto; Heron, Jon; Ramchandani, Paul; Wiles, Nicola; Murray, Lynne; Stein, Alan

2012-01-01

Background: Maternal depression is known to be associated with impairments in child cognitive development, although the effect of timing of exposure to maternal depression is unclear. Methods: Data collected for the Avon Longitudinal Study of Parents and Children, a longitudinal study beginning in pregnancy, included self-report measures of…

National Prevalence Rates of Bully Victimization among Students with Disabilities in the United States

ERIC Educational Resources Information Center

Blake, Jamilia J.; Lund, Emily M.; Zhou, Qiong; Kwok, Oi-man; Benz, Michael R.

2012-01-01

This study examined the prevalence rates of bully victimization and risk for repeated victimization among students with disabilities using the Special Education Elementary Longitudinal Study and the National Longitudinal Transition Study-2 longitudinal datasets. Results revealed that a prevalence rate ranging from 24.5% in elementary school to…

Fears in Czech Adolescents: A Longitudinal Study

ERIC Educational Resources Information Center

Michalcáková, Radka; Lacinová, Lenka; Kyjonková, Hana; Bouša, Ondrej; Jelínek, Martin

2013-01-01

The present study investigates developmental patterns of fear in adolescence. It is based on longitudinal data collected as a part of the European Longitudinal Study of Pregnancy and Childhood (ELSPAC) project. A total of 186 Czech adolescents (43% girls) were assessed repeatedly at the age of 11, 13, and 15 years. The free-response method was…

Reducing Bias Due to Systematic Attrition in Longitudinal Studies: The Benefits of Multiple Imputation

ERIC Educational Resources Information Center

Asendorpf, Jens B.; van de Schoot, Rens; Denissen, Jaap J. A.; Hutteman, Roos

2014-01-01

Most longitudinal studies are plagued by drop-out related to variables at earlier assessments (systematic attrition). Although systematic attrition is often analysed in longitudinal studies, surprisingly few researchers attempt to reduce biases due to systematic attrition, even though this is possible and nowadays technically easy. This is…

Nonlinear Gompertz Curve Models of Achievement Gaps in Mathematics and Reading

ERIC Educational Resources Information Center

Cameron, Claire E.; Grimm, Kevin J.; Steele, Joel S.; Castro-Schilo, Laura; Grissmer, David W.

2015-01-01

This study examined achievement trajectories in mathematics and reading from school entry through the end of middle school with linear and nonlinear growth curves in 2 large longitudinal data sets (National Longitudinal Study of Youth--Children and Young Adults and Early Childhood Longitudinal Study--Kindergarten Cohort [ECLS-K]). The S-shaped…

Paternal Alcoholism, Family Functioning, and Infant Mental Health

ERIC Educational Resources Information Center

Fitzgerald, Hiram E.; Eiden, Rina Das

2007-01-01

The authors share results from two longitudinal studies exploring the impact of father's alcohol use on child development. The Michigan Longitudinal Study (MLS) has followed a sample of alcoholic families with 3-5 year old children for 20 years. The Buffalo Longitudinal Study (BLS) has followed a sample of alcoholic and nonalcoholic families…

Longitudinal multigroup invariance analysis of the satisfaction with food-related life scale in university students.

PubMed

Schnettler, Berta; Miranda, Horacio; Miranda-Zapata, Edgardo; Salinas-Oñate, Natalia; Grunert, Klaus G; Lobos, Germán; Sepúlveda, José; Orellana, Ligia; Hueche, Clementina; Bonilla, Héctor

2017-06-01

This study examined longitudinal measurement invariance in the Satisfaction with Food-related Life (SWFL) scale using follow-up data from university students. We examined this measure of the SWFL in different groups of students, separated by various characteristics. Through non-probabilistic longitudinal sampling, 114 university students (65.8% female, mean age: 22.5) completed the SWFL questionnaire three times, over intervals of approximately one year. Confirmatory factor analysis was used to examine longitudinal measurement invariance. Two types of analysis were conducted: first, a longitudinal invariance by time, and second, a multigroup longitudinal invariance by sex, age, socio-economic status and place of residence during the study period. Results showed that the 3-item version of the SWFL exhibited strong longitudinal invariance (equal factor loadings and equal indicator intercepts). Longitudinal multigroup invariance analysis also showed that the 3-item version of the SWFL displays strong invariance by socio-economic status and place of residence during the study period over time. Nevertheless, it was only possible to demonstrate equivalence of the longitudinal factor structure among students of both sexes, and among those older and younger than 22 years. Generally, these findings suggest that the SWFL scale has satisfactory psychometric properties for longitudinal measurement invariance in university students with similar characteristics as the students that participated in this research. It is also possible to suggest that satisfaction with food-related life is associated with sex and age. Copyright © 2017 Elsevier Ltd. All rights reserved.

Stability and change in adult personality over 6 years: findings from the Victoria Longitudinal Study.

PubMed

Small, Brent J; Hertzog, Christopher; Hultsch, David F; Dixon, Roger A

2003-05-01

Data from the Victoria Longitudinal Study were used to examine the 6-year longitudinal stability of personality in older adults. Personality was measured with the NEO Personality Inventory. The longitudinal sample consisted of 223 adults initially ranging from 55 to 85 years of age. Longitudinal confirmatory factor analyses were used to examine the stability of individual differences in change over time, and the stability of the longitudinal factor structure. The results indicated both substantial stability at the level of individual differences in change, as well as significant individual differences in change that were related to age and gender. Finally, the factor structure of personality was invariant over time but did not approximate simple structure for the five dimensions of personality. Our study of 6-year personality development provided both (a). a confirmation of early significant stability findings and (b). unique evidence for significant individual differences in late adulthood.

Why Missing Data Matter in the Longitudinal Study of Adolescent Development: Using the 4-H Study to Understand the Uses of Different Missing Data Methods

ERIC Educational Resources Information Center

Jelicic, Helena; Phelps, Erin; Lerner, Richard M.

2010-01-01

The study of adolescent development rests on methodologically appropriate collection and interpretation of longitudinal data. While all longitudinal studies of adolescent development involve missing data, the methods to treat missingness that have been recommended most often focus on missing data from cross-sectional studies. The problems of…

Reading Fluency from Grade 2-6: A Longitudinal Examination

ERIC Educational Resources Information Center

Lipka, Orly

2017-01-01

The goal of this study was to examine oral word reading fluency from a developmental perspective in a longitudinal study of students from second grade to sixth grade. The sample consisted of native English speaking students that took part in a large longitudinal study. Participants were assessed on cognitive and literacy measures such as working…

Early Predictors of Adolescent Depression: A 7-Year Longitudinal Study

ERIC Educational Resources Information Center

Mazza, James J.; Abbott, Robert D.; Fleming, Charles B.; Harachi, Tracy W.; Cortes, Rebecca C.; Park, Jisuk; Haggerty, Kevin P.; Catalano, Richard F.

2009-01-01

This study examined the longitudinal relationship of early elementary predictors to adolescent depression 7 years later. The sample consisted of 938 students who have been part of a larger longitudinal study that started in 1993. Data collected from parents, teachers, and youth self-reports on early risk factors when students were in 1st and 2nd…

77 FR 22068 - Proposed Information Collection (Post-9/11 GI Bill Education Longitudinal Study Survey) Activity...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-12

... DEPARTMENT OF VETERANS AFFAIRS [OMB Control No. 2900-New (Post-9/11 GI Bill Longitudinal Study Survey)] Proposed Information Collection (Post-9/11 GI Bill Education Longitudinal Study Survey) Activity... information needed to determine the long-term outcomes of Veterans participating in VBA's Post-9/11GI Bill...

Investigation of 2-stage meta-analysis methods for joint longitudinal and time-to-event data through simulation and real data application.

PubMed

Sudell, Maria; Tudur Smith, Catrin; Gueyffier, François; Kolamunnage-Dona, Ruwanthi

2018-04-15

Joint modelling of longitudinal and time-to-event data is often preferred over separate longitudinal or time-to-event analyses as it can account for study dropout, error in longitudinally measured covariates, and correlation between longitudinal and time-to-event outcomes. The joint modelling literature focuses mainly on the analysis of single studies with no methods currently available for the meta-analysis of joint model estimates from multiple studies. We propose a 2-stage method for meta-analysis of joint model estimates. These methods are applied to the INDANA dataset to combine joint model estimates of systolic blood pressure with time to death, time to myocardial infarction, and time to stroke. Results are compared to meta-analyses of separate longitudinal or time-to-event models. A simulation study is conducted to contrast separate versus joint analyses over a range of scenarios. Using the real dataset, similar results were obtained by using the separate and joint analyses. However, the simulation study indicated a benefit of use of joint rather than separate methods in a meta-analytic setting where association exists between the longitudinal and time-to-event outcomes. Where evidence of association between longitudinal and time-to-event outcomes exists, results from joint models over standalone analyses should be pooled in 2-stage meta-analyses. © 2017 The Authors. Statistics in Medicine Published by John Wiley & Sons Ltd.

Strategies for Longitudinal Analysis of the Career Paths of Beginning Teachers: Results from the First through Fourth Waves of the 2007-08 Beginning Teacher Longitudinal Study. Research and Development Report. NCES 2013-336

ERIC Educational Resources Information Center

Gray, Lucinda; Brauen, Marsha

2013-01-01

To learn more about the early career patterns of beginning teachers, the National Center for Education Statistics (NCES) of the Institute of Education Sciences within the U.S. Department of Education undertook the Beginning Teacher Longitudinal Study (BTLS). The ultimate purpose of this report is to develop a strategy for the longitudinal analysis…

Longitudinal axons are guided by Slit/Robo signals from the floor plate.

PubMed

Mastick, Grant S; Farmer, W Todd; Altick, Amy L; Nural, Hikmet Feyza; Dugan, James P; Kidd, Thomas; Charron, Frederic

2010-01-01

Longitudinal axons grow long distances along precise pathways to connect major CNS regions. However, during embryonic development, it remains largely undefined how the first longitudinal axons choose specific positions and grow along them. Here, we review recent evidence identifying a critical role for Slit/Robo signals to guide pioneer longitudinal axons in the embryonic brain stem. These studies indicate that Slit/Robo signals from the floor plate have dual functions: to repel longitudinal axons away from the ventral midline, and also to maintain straight longitudinal growth. These dual functions likely cooperate with other guidance cues to establish the major longitudinal tracts in the brain.

Using a Large Scale Computational Model to Study the Effect of Longitudinal and Radial Electrical Coupling in the Cochlea

NASA Astrophysics Data System (ADS)

Mistrík, Pavel; Ashmore, Jonathan

2009-02-01

We describe a large scale computational model of electrical current flow in the cochlea which is constructed by a flexible Modified Nodal Analysis algorithm to incorporate electrical components representing hair cells and the intercellular radial and longitudinal current flow. The model is used as a laboratory to study the effects of changing longitudinal gap junctional coupling, and shows the way in which cochlear microphonic spreads and tuning is affected. The process for incorporating mechanical longitudinal coupling and feedback is described. We find a difference in tuning and attenuation depending on whether longitudinal or radial couplings are altered.

College Women's Female Friendships: A Longitudinal View

ERIC Educational Resources Information Center

Aleman, Ana M. Martinez

2010-01-01

This article presents a longitudinal qualitative study of the cognitive value of female friendships formed in college and seeks to appraise the meaning of the phenomenon for the participants. To grasp the temporal effects of the longitudinal data in this study, the author examines and assesses the relevant developmental literature, particularly…

Lo Gnomone Clementino Astronomia Meridiana in Basilica

NASA Astrophysics Data System (ADS)

Sigismondi, Costantino

2014-05-01

Costruito per chiara volontà del papa 70 anni dopo il caso Galileo, lo Gnomone Clementino è un grande telescopio solare che non fa uso di lenti a 92 anni dall’invenzione del cannocchiale. Queste due caratteristiche basterebbero da sole a giustificare l’interesse verso questo strumento. L’astronomia meridiana è alla base dell’astrometria e dell’astrofisica moderna. Lo Gnomone Clementino sta oggi all’astronomia, come il veliero “Amerigo Vespucci” sta alla Marina Italiana. E’ possibile svolgere ogni genere di osservazione e studio su questo strumento, e dal 2002 vi tengo lezioni teorico-pratiche del corso di Storia dell’Astronomia e La Terra nel Sistema Solare della Sapienza, Università di Roma, Facoltà di Lettere e Filosofia. Questo testo aggiunge alcuni tasselli alla ricerca storica sulla meridiana, appoggiandosi, com’è naturale, sulle spalle di giganti che mi hanno preceduto in questi studi. In particolare la misura dell’azimut della meridiana, ed il suo inquadramento tra gli strumenti simili ed alcuni studi di astrometria sui dati del 1701-1703 di Bianchini, che sono apparsi fin’ora soltanto su riviste specializzate ed in Inglese vengono qui proposti in Italiano e semplificati, per valorizzare sempre più questa straordinaria opera d’arte e di scienza.

"Old Age and Loneliness: Cross-Sectional and Longitudinal Analyses in the Tampere Longitudinal Study on Aging"

ERIC Educational Resources Information Center

Jylha, Marja

2004-01-01

The purpose of this study was to examine whether older age is associated with increasing loneliness in people aged 60 and over. Data came from TamELSA, a population-based prospective longitudinal study in Tampere, Finland. The followup time was 20 years. Loneliness was measured by a single question--"Do you feel lonely?"--with the…

Higher Weight, Lower Education: A Longitudinal Association between Adolescents' Body Mass Index and Their Subsequent Educational Achievement Level?

ERIC Educational Resources Information Center

Larsen, Junilla K.; Kleinjan, Marloes; Engels, Rutger C. M. E.; Fisher, Jennifer O.; Hermans, Roel

2014-01-01

Background: The purpose of this study was to examine the association between adolescents' body mass index (BMI) z-scores and their subsequent level of schooling, extending previous longitudinal research by using objectively measured weight and height data. Methods: A longitudinal study with 3 study waves (1-year intervals) involving 1248 Dutch…

How Does Longitudinally Measured Maternal Expressed Emotion Affect Internalizing and Externalizing Symptoms of Adolescents from the General Community?

ERIC Educational Resources Information Center

Hale, William W., III; Keijsers, Loes; Klimstra, Theo A.; Raaijmakers, Quinten A. W.; Hawk, Skyler; Branje, Susan J. T.; Frijns, Tom; Wijsbroek, Saskia A. M.; van Lier, Pol; Meeus, Wim H. J.

2011-01-01

Background: In previous studies, maternal expressed emotion (EE) has been found to be a good predictor of the course of adolescent internalizing and externalizing symptoms. However, these studies have been cross-section as opposed to longitudinal. The goal of this study is to examine longitudinal data of perceived maternal EE and adolescent…

High School Longitudinal Study of 2009 (HSLS:09): Base-Year Data File Documentation. NCES 2011-328

ERIC Educational Resources Information Center

Ingels, Steven J.; Pratt, Daniel J.; Herget, Deborah R.; Burns, Laura J.; Dever, Jill A.; Ottem, Randolph; Rogers, James E.; Jin, Ying; Leinwand, Steve

2011-01-01

The High School Longitudinal Study of 2009 (HSLS:09) is the fifth in a series of National Center for Education Statistics (NCES) secondary longitudinal studies. The core research questions for HSLS:09 explore secondary to postsecondary transition plans and the evolution of those plans; the paths into and out of science, technology, engineering,…

Longitudinal joint study.

DOT National Transportation Integrated Search

2001-09-01

In previous years there has been a problem with longitudinal joint : deterioration, due in part to poor construction techniques. : The degradation of the longitudinal joints has increased the cost of : maintaining these projects and caused unnecessar...

Novel and emerging strategies for longitudinal data collection.

PubMed

Udtha, Malini; Nomie, Krystle; Yu, Erica; Sanner, Jennifer

2015-03-01

To describe novel and emerging strategies practiced globally in research to improve longitudinal data collection. In research studies, numerous strategies such as telephone interviews, postal mailing, online questionnaires, and electronic mail are traditionally utilized in longitudinal data collection. However, due to technological advances, novel and emerging strategies have been applied to longitudinal data collection, such as two-way short message service, smartphone applications (or "apps"), retrieval capabilities applied to the electronic medical record, and an adapted cloud interface. In this review, traditional longitudinal data collection strategies are briefly described, emerging and novel strategies are detailed and explored, and information regarding the impact of novel methods on participant response rates, the timeliness of participant responses, and cost is provided. We further discuss how these novel and emerging strategies affect longitudinal data collection and advance research, specifically nursing research. Evidence suggests that the novel and emerging longitudinal data collection strategies discussed in this review are valuable approaches to consider. These strategies facilitate collecting longitudinal research data to better understand a variety of health-related conditions. Future studies, including nursing research, should consider using novel and emerging strategies to advance longitudinal data collection. A better understanding of novel and emerging longitudinal data collection strategies will ultimately improve longitudinal data collection as well as foster research efforts. Nurse researchers, along with all researchers, must be aware of and consider implementing novel and emerging strategies to ensure future healthcare research success. © 2014 Sigma Theta Tau International.

Studies on mass attenuation coefficient, effective atomic number and electron density of some thermoluminescent dosimetric compounds

NASA Astrophysics Data System (ADS)

Önder, P.; Turşucu, A.; Demir, D.; Gürol, A.

2012-12-01

Mass attenuation coefficient, μm , effective atomic number, Zeff, and effective electron density, Nel, were determined experimentally and theoretically for some thermoluminescent dosimetric (TLD) compounds such as MgSO4, CdSO4, Al2O3, Mg2SiO4, ZnSO4, CaSO4, CaF2, NaSO4, Na4P2O7, Ca5F(PO4)3, SiO2, CaCO3 and BaSO4 at 8.04, 8.91, 13.37, 14.97, 17.44, 19.63, 22.10, 24.90, 30.82, 32.06, 35.40, 36.39, 37.26, 43.74, 44.48, 50.38, 51.70, 53.16, 80.99, 276.40, 302.85, 356.01, 383.85 and 661.66 keV photon energies by using an HPGe detector with a resolution of 182 eV at 5.9 keV. The theoretical mass attenuation coefficients were estimated using mixture rule. The calculated values were compared with the experimental values for all compounds. Good agreement has been observed between experimental and theoretical values within experimental uncertainties.

Gamma rays shielding parameters for white metal alloys

NASA Astrophysics Data System (ADS)

Kaur, Taranjot; Sharma, Jeewan; Singh, Tejbir

2018-05-01

In the present study, an attempt has been made to check the feasibility of white metal alloys as gamma rays shielding materials. Different combinations of cadmium, lead, tin and zinc were used to prepare quaternary alloys Pb60Sn20ZnxCd20-x (where x = 5, 10, 15) using melt quench technique. These alloys were also known as white metal alloys because of its shining appearance. The density of prepared alloys has been measured using Archimedes Principle. Gamma rays shielding parameters viz. mass attenuation coefficient (µm), effective atomic number (Zeff), electron density (Nel), Mean free path (mfp), Half value layer (HVL) and Tenth value layer (TVL) has been evaluated for these alloys in the wide energy range from 1 keV to 100 GeV. The WinXCom software has been used for obtaining mass attenuation coefficient values for the prepared alloys in the given energy range. The effective atomic number (Zeff) has been assigned to prepared alloys using atomic to electronic cross section ratio method. Further, the variation of various shielding parameters with photon energy has been investigated for the prepared white metal alloys.

Substance Use as a Longitudinal Predictor of the Perpetration of Teen Dating Violence

ERIC Educational Resources Information Center

Temple, Jeff R.; Shorey, Ryan C.; Fite, Paula; Stuart, Gregory L.; Le, Vi Donna

2013-01-01

The prevention of teen dating violence is a major public health priority. However, the dearth of longitudinal studies makes it difficult to develop programs that effectively target salient risk factors. Using a school-based sample of ethnically diverse adolescents, this longitudinal study examined whether substance use (alcohol, marijuana, and…

Transformative Learning in Medical Education: Context Matters, a South Australian Longitudinal Study

ERIC Educational Resources Information Center

Greenhill, Jenenne; Richards, Janet Noreen; Mahoney, Sarah; Campbell, Narelle; Walters, Lucie

2018-01-01

This longitudinal study followed the clinical learning journey of 20 medical students over 4 years, from the beginning of their clinical immersion, through one of the three different clinical placement models: block rotation, longitudinal integrated clerkship, or community- and hospital-integrated learning, and then into Year 4 and the intern year…

Executive Function in Early Childhood: Longitudinal Measurement Invariance and Developmental Change

ERIC Educational Resources Information Center

Willoughby, Michael T.; Wirth, R. J.; Blair, Clancy B.

2012-01-01

This study tested the longitudinal measurement invariance and developmental changes of a newly developed battery of executive function (EF) tasks for use in early childhood. The battery was administered in the Family Life Project--a prospective longitudinal study (N = 1,292) of families who were oversampled from low-income and African American…

Use of Missing Data Methods in Longitudinal Studies: The Persistence of Bad Practices in Developmental Psychology

ERIC Educational Resources Information Center

Jelicic, Helena; Phelps, Erin; Lerner, Richard M.

2009-01-01

Developmental science rests on describing, explaining, and optimizing intraindividual changes and, hence, empirically requires longitudinal research. Problems of missing data arise in most longitudinal studies, thus creating challenges for interpreting the substance and structure of intraindividual change. Using a sample of reports of longitudinal…

Cultural Orientation Trajectories and Substance Use: Findings from a Longitudinal Study of Mexican-Origin Youth

ERIC Educational Resources Information Center

Cruz, Rick A.; King, Kevin M.; Cauce, Ana M.; Conger, Rand D.; Robins, Richard W.

2017-01-01

Cultural adaptation may influence Latino youth substance use (SU) development, yet few longitudinal studies have examined cultural change over time and adolescent SU outcomes. Using longitudinal data collected annually across ages 10-16 from 674 Mexican-origin youth (50% female), the authors characterized cultural adaptation patterns for language…

A Longitudinal Study of Children's Social Behaviors and Their Causal Relationship to Reading Growth

ERIC Educational Resources Information Center

Lim, Hyo Jin; Kim, Junyeop

2011-01-01

This paper aims at investigating the causal effects of social behaviors on subsequent reading growth in elementary school, using the "Early Childhood Longitudinal Study-Kindergarten" ("ECLS-K") data. The sample was 8,869 subjects who provided longitudinal measures of reading IRT scores from kindergarten (1998-1999) to fifth…

Changes in HRM in Europe: A Longitudinal Comparative Study among 18 European Countries

ERIC Educational Resources Information Center

Nikandrou, Irene; Apospori, Eleni; Papalexandris, Nancy

2005-01-01

Purpose: To examine HRM strategies and practices and HRM position within organizations in various cultural, economic and sociopolitical contexts from a longitudinal perspective. Design/methodology/approach: The study uses the 1995 and 1999 Cranet data in a longitudinal methodological framework to explore the changes and trends in 18 European…

The Multiple-Institution Database for Investigating Engineering Longitudinal Development: An Experiential Case Study of Data Sharing and Reuse

ERIC Educational Resources Information Center

Ohland, Matthew W.; Long, Russell A.

2016-01-01

Sharing longitudinal student record data and merging data from different sources is critical to addressing important questions being asked of higher education. The Multiple-Institution Database for Investigating Engineering Longitudinal Development (MIDFIELD) is a multi-institution, longitudinal, student record level dataset that is used to answer…

Autism Spectrum Disorder and Autistic Traits in the Avon Longitudinal Study of Parents and Children: Precursors and Early Signs

ERIC Educational Resources Information Center

Bolton, Patrick F.; Golding, Jean; Emond, Alan; Steer, Colin D.

2012-01-01

Objective: To chart the emergence of precursors and early signs of autism spectrum disorder (ASD) and autistic traits in the Avon Longitudinal Study of Parents and Children, a prospective longitudinal cohort study of the surviving offspring of 14,541 pregnant women from southwestern England with an expected delivery date between April 1991 and…

An Analysis of Pedagogical Moves for Facilitating the Development of In-Service Middle-School Mathematics Teachers' Recognition of Reasoning

ERIC Educational Resources Information Center

Cipriani, Phyllis J.

2017-01-01

A constructivist approach for teaching and learning mathematics was the foundation for a longitudinal study at Rutgers University in 1987 (Maher, 2011). One of the objectives of the longitudinal study was to provide an environment where students solve problems in collaborative groups (Maher, 2011). Videos from the longitudinal study are stored in…

The Etiology of Variation in Language Skills Changes with Development: A Longitudinal Twin Study of Language from 2 to 12 Years

ERIC Educational Resources Information Center

Hayiou-Thomas, Marianna E.; Dale, Philip S.; Plomin, Robert

2012-01-01

The present study is the first long-term longitudinal examination of the etiology of individual differences in language from early childhood through to adolescence. We applied a multivariate latent factor genetic model to longitudinal data from the Twins Early Development Study in order to (a) compare the magnitude of genetic and environmental…

Retention of Children and Their Families in the Longitudinal Outcome Study of the Comprehensive Community Mental Health Services for Children and Their Families Program: A Multilevel Analysis

ERIC Educational Resources Information Center

Gebreselassie, Tesfayi; Stephens, Robert L.; Maples, Connie J.; Johnson, Stacy F.; Tucker, Alyce L.

2014-01-01

Predictors of retention of participants in a longitudinal study and heterogeneity between communities were investigated using a multilevel logistic regression model. Data from the longitudinal outcome study of the national evaluation of the Comprehensive Community Mental Health Services for Children and Their Families program and information on…

Using Hand Grip Force as a Correlate of Longitudinal Acceleration Comfort for Rapid Transit Trains

PubMed Central

Guo, Beiyuan; Gan, Weide; Fang, Weining

2015-01-01

Longitudinal acceleration comfort is one of the essential metrics used to evaluate the ride comfort of train. The aim of this study was to investigate the effectiveness of using hand grip force as a correlate of longitudinal acceleration comfort of rapid transit trains. In the paper, a motion simulation system was set up and a two-stage experiment was designed to investigate the role of the grip force on the longitudinal comfort of rapid transit trains. The results of the experiment show that the incremental grip force was linearly correlated with the longitudinal acceleration value, while the incremental grip force had no correlation with the direction of the longitudinal acceleration vector. The results also show that the effects of incremental grip force and acceleration duration on the longitudinal comfort of rapid transit trains were significant. Based on multiple regression analysis, a step function model was established to predict the longitudinal comfort of rapid transit trains using the incremental grip force and the acceleration duration. The feasibility and practicably of the model was verified by a field test. Furthermore, a comparative analysis shows that the motion simulation system and the grip force based model were valid to support the laboratory studies on the longitudinal comfort of rapid transit trains. PMID:26147730

Maintaining Superior Follow-Up Rates in a Longitudinal Study: Experiences from the College Life Study

PubMed Central

Vincent, Kathryn B.; Kasperski, Sarah J.; Caldeira, Kimberly M.; Garnier-Dykstra, Laura M.; Pinchevsky, Gillian M.; O’Grady, Kevin E.; Arria, Amelia M.

2011-01-01

Longitudinal studies are often considered to be a gold standard for research, but the operational management of such studies is not often discussed in detail; this paper describes strategies used to track and maintain high levels of participation in a longitudinal study involving annual personal interviews with a cohort of 1,253 undergraduates (first-time, first-year students at time of enrollment) at a large public mid-Atlantic university. PMID:22247739

[Health expenditure for prevention in Italy (2006-2013): descriptive analysis, regional trends and international comparisons].

PubMed

Signorelli, Carlo; Odone, Anna; Bianco, Daniela; Di Vivo, Natalia; Bevere, Francesco

2016-01-01

Il dato dell'Organizzazione per la cooperazione e lo sviluppo economico (OCSE) del 2012, che indicava l'Italia come il Paese con la più bassa spesa in prevenzione sanitaria, ha dato lo spunto per una raccolta sistematica e un'analisi critica dei flussi disponibili sulla spesa per le attività di prevenzione in Italia. Le statistiche correnti di spesa sanitaria sono raccolte centralmente dall'Agenzia nazionale per i servizi sanitari regionali (Agenas) attraverso i modelli di rilevazione dei costi dei livelli essenziali di assistenza (LEA) delle aziende USL. Le tre macroaree dei LEA sono: assistenza distrettuale, assistenza ospedaliera e assistenza sanitaria collettiva in ambiente di vita e di lavoro. Le spese per la prevenzione rientrano in quest'ultima e sono ripartite nelle seguenti voci: attività di prevenzione rivolte alle persone, igiene degli alimenti e della nutrizione, igiene e sanità pubblica, prevenzione e sicurezza negli ambienti di lavoro, sanità pubblica veterinaria, attività medico-legale per finalità pubblica. Tra il 2006 e il 2013, ultimo dato disponibile, la spesa per le attività di prevenzione del Servizio sanitario nazionale (SSN) è rimasta costante in rapporto alla spesa sanitaria totale (4,2%), pari a 4,9 miliardi nel 2013. Nel periodo di studio considerato (2006-2013) appaiono in aumento le spese per le attività rivolte alle persone (+8,7%), attribuibili soprattutto a vaccinazioni e screening, e in diminuzione le attività di igiene pubblica (-5,7%) e quelle della sanità pubblica veterinaria (-3,8%). I confronti internazionali indicano una spesa per la prevenzione del 2,9% rispetto alla spesa sanitaria totale, costante negli anni e nella media dei Paesi OCSE. Per la prevenzione, l'Italia spende tanto quanto i Paesi che non possiedono un servizio sanitario pubblico; il dato risulta inferiore del 5% rispetto alla programmazione nazionale, con poche eccezioni e molta variabilità regionale all'interno delle componenti delle voci di spesa. In questo contesto si sottolinea l'importanza di investire maggiori risorse nella pianificazione e nell'implementazione di interventi preventivi di provata efficacia e costo-efficacia.

Using Longitudinal Assessment Data to Improve Retention and Student Experiences

ERIC Educational Resources Information Center

Trosset, Carol; Weisler, Steven

2010-01-01

The Wabash National Study of Liberal Arts Education presents a longitudinal analysis of how students change on a number of scales that purport to measure many of the outcomes of liberal learning over the span of a college education. The Wabash Study is designed to collect information longitudinally from students at the beginning and end of their…

Predicting Family Poverty and Other Disadvantaged Conditions for Child Rearing from Childhood Aggression and Social Withdrawal: A 30-Year Longitudinal Study

ERIC Educational Resources Information Center

Serbin, Lisa A.; Temcheff, Caroline E.; Cooperman, Jessica M.; Stack, Dale M.; Ledingham, Jane; Schwartzman, Alex E.

2011-01-01

This 30-year longitudinal study examined pathways from problematic childhood behavior patterns to future disadvantaged conditions for family environment and child rearing in adulthood. Participants were mothers (n = 328) and fathers (n = 222) with lower income backgrounds participating in the ongoing Concordia Longitudinal Risk Project. Structural…

Longitudinal Pathways between Maternal Mental Health in Infancy and Offspring Romantic Relationships in Adulthood: A 30-Year Prospective Study

ERIC Educational Resources Information Center

Slominski, Lisa; Sameroff, Arnold; Rosenblum, Katherine; Kasser, Tim

2011-01-01

Longitudinal pathways between maternal mental health in infancy and offspring romantic relationship outcomes in adulthood were examined using a 30-year prospective longitudinal study of 196 mothers and their children. Structural equation modeling revealed that maternal mental health at 30 months was related to offspring relationship status and…

Longitudinal Associations between Observed and Perceived Neighborhood Food Availability and Body Mass Index in a Multiethnic Urban Sample

ERIC Educational Resources Information Center

Zenk, Shannon N.; Mentz, Graciela; Schulz, Amy J.; Johnson-Lawrence, Vicki; Gaines, Causandra R.

2017-01-01

Introduction: Blacks, Hispanics, and women of lower socioeconomic status tend to have a higher risk of obesity. Numerous studies over the past decade examined the role of the neighborhood food environment in body weight. However, few were longitudinal. Purpose: This longitudinal study examined whether multiple measures of neighborhood food…

Longitudinal Effects of Perceived Maternal Approval on Sexual Behaviors of Asian and Pacific Islander (API) Young Adults

ERIC Educational Resources Information Center

Hahm, Hyeouk; Lee, Jieha; Zerden, Lisa; Ozonoff, Al; Amodeo, Maryann; Adkins, Chris

2008-01-01

Data were obtained from the National Longitudinal Study of Adolescent Health to examine the longitudinal association between Asian and Pacific Islander (API) adolescents' perceptions of maternal approval of their sexual activity and contraception use, and four sexual outcomes during young adulthood. The study includes a nationally representative…

Longitudinal Relations between Ethnic/Racial Identity Process and Content: Exploration, Commitment, and Salience among Diverse Adolescents

ERIC Educational Resources Information Center

Wang, Yijie; Douglass, Sara; Yip, Tiffany

2017-01-01

The present study bridges the process and content perspectives of ethnic/racial identity (ERI) by examining the longitudinal links between identity process (i.e., exploration, commitment) and a component of identity content, salience. Data were drawn from a 4-wave longitudinal study of 405 ethnically/racially diverse adolescents (63% female) from…

LADES: a software for constructing and analyzing longitudinal designs in biomedical research.

PubMed

Vázquez-Alcocer, Alan; Garzón-Cortes, Daniel Ladislao; Sánchez-Casas, Rosa María

2014-01-01

One of the most important steps in biomedical longitudinal studies is choosing a good experimental design that can provide high accuracy in the analysis of results with a minimum sample size. Several methods for constructing efficient longitudinal designs have been developed based on power analysis and the statistical model used for analyzing the final results. However, development of this technology is not available to practitioners through user-friendly software. In this paper we introduce LADES (Longitudinal Analysis and Design of Experiments Software) as an alternative and easy-to-use tool for conducting longitudinal analysis and constructing efficient longitudinal designs. LADES incorporates methods for creating cost-efficient longitudinal designs, unequal longitudinal designs, and simple longitudinal designs. In addition, LADES includes different methods for analyzing longitudinal data such as linear mixed models, generalized estimating equations, among others. A study of European eels is reanalyzed in order to show LADES capabilities. Three treatments contained in three aquariums with five eels each were analyzed. Data were collected from 0 up to the 12th week post treatment for all the eels (complete design). The response under evaluation is sperm volume. A linear mixed model was fitted to the results using LADES. The complete design had a power of 88.7% using 15 eels. With LADES we propose the use of an unequal design with only 14 eels and 89.5% efficiency. LADES was developed as a powerful and simple tool to promote the use of statistical methods for analyzing and creating longitudinal experiments in biomedical research.

Age-related slowing of digit symbol substitution revisited: what do longitudinal age changes reflect?

PubMed

MacDonald, Stuart W S; Hultsch, David F; Strauss, Esther; Dixon, Roger A

2003-05-01

A previous investigation reported that cross-sectional age differences in Digit Symbol Substitution (DSS) test performance reflect declines in perceptual processing speed. Support for the tenability of the processing speed hypothesis requires examining whether longitudinal age-related change in DSS performance is largely mediated by changes in speed. The present study used data from the Victoria Longitudinal Study to examine patterns and predictors of longitudinal change in DSS for 512 older adults (M(age) = 68.37 years, SD = 7.43). On the basis of multilevel modeling, baseline DSS performance was poorer for older participants and men, with longitudinal declines more pronounced with increasing age and decreasing speed. In contrast to the present cross-sectional findings, statistical control of change trajectories in perceptual speed using the same data did not substantially attenuate age changes. These discrepancies suggest different sources of variance may underlie cross-sectional age differences and longitudinal age changes for DSS.

Making an unknown unknown a known unknown: Missing data in longitudinal neuroimaging studies.

PubMed

Matta, Tyler H; Flournoy, John C; Byrne, Michelle L

2017-10-28

The analysis of longitudinal neuroimaging data within the massively univariate framework provides the opportunity to study empirical questions about neurodevelopment. Missing outcome data are an all-to-common feature of any longitudinal study, a feature that, if handled improperly, can reduce statistical power and lead to biased parameter estimates. The goal of this paper is to provide conceptual clarity of the issues and non-issues that arise from analyzing incomplete data in longitudinal studies with particular focus on neuroimaging data. This paper begins with a review of the hierarchy of missing data mechanisms and their relationship to likelihood-based methods, a review that is necessary not just for likelihood-based methods, but also for multiple-imputation methods. Next, the paper provides a series of simulation studies with designs common in longitudinal neuroimaging studies to help illustrate missing data concepts regardless of interpretation. Finally, two applied examples are used to demonstrate the sensitivity of inferences under different missing data assumptions and how this may change the substantive interpretation. The paper concludes with a set of guidelines for analyzing incomplete longitudinal data that can improve the validity of research findings in developmental neuroimaging research. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

Inter-relationships among alternative definitions of feed efficiency in grazing lactating dairy cows.

PubMed

Hurley, A M; López-Villalobos, N; McParland, S; Kennedy, E; Lewis, E; O'Donovan, M; Burke, J L; Berry, D P

2016-01-01

International interest in feed efficiency, and in particular energy intake and residual energy intake (REI), is intensifying due to a greater global demand for animal-derived protein and energy sources. Feed efficiency is a trait of economic importance, and yet is overlooked in national dairy cow breeding goals. This is due primarily to a lack of accurate data on commercial animals, but also a lack of clarity on the most appropriate definition of the feed intake and utilization complex. The objective of the present study was to derive alternative definitions of energetic efficiency in grazing lactating dairy cows and to quantify the inter-relationships among these alternative definitions. Net energy intake (NEI) from pasture and concentrate intake was estimated up to 8 times per lactation for 2,693 lactations from 1,412 Holstein-Friesian cows. Energy values of feed were based on the French Net Energy system where 1 UFL is the net energy requirements for lactation equivalent of 1kg of air-dry barley. A total of 8,183 individual feed intake measurements were available. Energy balance was defined as the difference between NEI and energy expenditure. Efficiency traits were either ratio-based or residual-based; the latter were derived from least squares regression models. Residual energy intake was defined as NEI minus predicted energy to fulfill the requirements for the various energy sinks. The energy sinks (e.g., NEL, metabolic live weight) and additional contributors to energy kinetics (e.g., live weight loss) combined, explained 59% of the variation in NEI, implying that REI represented 41% of the variance in total NEI. The most efficient 10% of test-day records, as defined by REI (n=709), on average were associated with a 7.59 UFL/d less NEI (average NEI of the entire population was 16.23 UFL/d) than the least efficient 10% of test-day records based on REI (n=709). Additionally, the most efficient 10% of test-day records, as defined by REI, were associated with superior energy conversion efficiency (ECE, i.e., NEL divided by NEI; ECE=0.55) compared with the least efficient 10% of test-day records (ECE=0.33). Moreover, REI was positively correlated with energy balance, implying that more negative REI animals (i.e., deemed more efficient) are expected to be, on average, in greater negative energy balance. Many of the correlations among the 14 defined efficiency traits differed from unity, implying that each trait is measuring a different aspect of efficiency. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Chemical characterization, energy values, protein and carbohydrate fractions, degradation kinetics of frost damaged wheat (with severely overall weight loss) in ruminants.

PubMed

Yu, Peiqiang; Racz, Vern

2009-04-01

In Canada, frost damage can result in millions of tonnes of wheat that is not suitable for human consumption (such wheat is referred to as 'frozen') each year. There is a need to systematically evaluate the nutritive value of frozen wheat for ruminants. So far, little research has been conducted to determine the magnitude of the differences in nutritive value between frozen and normal wheat. The objectives of this study were to compare frozen wheat and normal wheat (AC Barrie) in terms of (i) chemical characteristics; (ii) protein and carbohydrate fractions; (iii) energy value; and (iv) rumen degradation kinetics. The results showed that the overall yield losses of the frozen wheat were around 24%. The frozen wheat was significantly lower (P < 0.05) in starch (47 vs. 62%DM), non-structural carbohydrates (60 vs. 70%DM), and non-protein N (63 vs. 93%SCP); and higher (P < 0.05) in crude fat (3 vs. 2%DM), acid (6 vs. 2%DM), neutral detergent fiber (22 vs. 10%DM), lignin (2 vs. 1%DM), acid (3 vs. 1%CP) and neutral detergent insoluble CP (19 vs. 14%CP). The frozen wheat was also lower in (P < 0.05) energy (TDN, DE(3X), ME(3X,) NEL(3X), DE(4X), ME(4X,) NEL(4X) for dairy; ME, NE(m), and NE(g) beef cattle). After partitioning of protein and carbohydrate (CHO) subfractions, the results showed that the frozen wheat was lower (P < 0.05) in the intermediately degradable CP (PB2: 47 vs. 59%CP); and higher in rapidly degradable CP (PB1: 12 vs. 2%CP) and unavailable CP (PC: 3 vs. 1%CP). The frozen wheat was also lower (P < 0.05) in intermediately degradable CHO (CB1: 60 vs. 77%CHO); and higher (P < 0.05) in slowly degradable CHO (CB2: 20 vs. 8%CHO) and unavailable CHO (CC: 5 vs. 2%CHO). The in situ results showed that the frozen wheat had different patterns in rumen degradation kinetics of protein and starch. The extent of the changes varied according to the specific nutrient examined. In conclusion, the frozen wheat differed in chemical characteristics, TDN and energy values, protein and carbohydrate fractions and in situ degradation behavior from normal wheat. The chemical and nutritional characterization of wheat was highly associated with climate condition (frost damage). The frost damage to the wheat reduced nutrient content and availability and thus reduced nutrient supply to ruminants.

Longitudinal Course of Depression Scores with and without Insomnia in Non-Depressed Individuals: A 6-Year Follow-Up Longitudinal Study in a Korean Cohort

PubMed Central

Suh, Sooyeon; Kim, Hyun; Yang, Hae-Chung; Cho, Eo Rin; Lee, Seung Ku; Shin, Chol

2013-01-01

Study Objective: This is a population-based longitudinal study that followed insomnia symptoms over a 6-year period in non-depressed individuals. The purpose of the study was to (1) investigate the longitudinal course of depression based on number of insomnia episodes; and (2) describe longitudinal associations between insomnia and depression, and insomnia and suicidal ideation. Design: Population-based longitudinal study. Setting: Community-based sample from the Korean Genome and Epidemiology Study (KoGES). Participants: 1,282 non-depressed individuals (44% male, mean age 52.3 ± 7.14 years) Measurements and Results: This study prospectively assessed insomnia, depression, and suicidal ideation with 4 time points. Individuals were classified into no insomnia (NI), single episode insomnia (SEI), and persistent insomnia (PI; ≥ insomnia at 2+ time points) groups based on number of times insomnia was indicated. Mixed effects modeling indicated that depression scores increased significantly faster in the PI group compared to the NI (P < 0.001) and SEI (P = 0.02) groups. Additionally, the PI group had significantly increased odds of depression as compared to NI or SEI (OR 2.44, P = 0.001) groups, with 18.7% meeting criteria for depression compared to the NI (5.3%) and SEI (11.6%) groups at end point. The PI group also had significantly increased odds of suicidal ideation as compared to NI or SEI (OR 1.86, P = 0.002) groups. Conclusions: Persistent insomnia significantly increases the rate in which depression occurs over time in non-depressed individuals, which ultimately leads to higher risk for depression. Additionally, having persistent insomnia also increased the risk of suicidal ideation. Citation: Suh S; Kim H; Yang HC; Cho ER; Lee SK; Shin C. Longitudinal course of depression scores with and without insomnia in non-depressed individuals: a 6-year follow-up longitudinal study in a Korean cohort. SLEEP 2013;36(3):369-376. PMID:23449814

A Longitudinal Study of Growth and Development and the Incidence of Physical Defects at Ages 9 and 10. A Progress Report to the Bernard van Leer Foundation on the Growth and Development Study of the Mt. Druitt Longitudinal Study.

ERIC Educational Resources Information Center

Clark, Anne; O'Brien, Peter

A longitudinal comparative study was made of the physical growth and development of Australian fourth-grade students from low, medium, and high socioeconomic groups. Specific questions addressed were (1) Do children differing in socioeconomic status differ in anthropometric characteristics and incidence of physical defects? (2) What is the…

Retention strategies in longitudinal studies with emerging adults.

PubMed

Hanna, Kathleen M; Scott, Linda L; Schmidt, Karen K

2014-01-01

The purpose of this report was to describe retention strategies that were useful and those that were not in a longitudinal study of emerging adults. A longitudinal study examining the transition to young adulthood among emerging adults with type 1 diabetes, which had success in retention, provided the context for describing retention strategies. A challenge in longitudinally designed studies is retention of participants because the loss decreases power for statistical analysis. Given that emerging adulthood is a period of instability, retention is particularly challenging among this population. However, longitudinal studies are the best way to understand developmental changes, and it is also important to increase our knowledge of health outcomes during emerging adulthood. Retention strategies used in the study are described, including promoting a positive relationship with participants, maintaining contact with participants, having a study staff with good interpersonal skills, using incentives, conveying respect for participants, and using user-friendly data collection. Useful strategies to promote a positive relationship included sending cards and newsletters to participants, maintaining consistency of contact person, and expressing appreciation for participant's time and effort. Useful strategies for maintaining contact with participants included obtaining contact information at every data collection point, maintaining birth dates and chart numbers in tracking databases, monitoring returned mail, and using Web search engines. Other useful strategies were providing incentives to participants, employing staff with good interpersonal skills, providing participants with choices when appropriate, and using user-friendly data collection. One strategy, using contests, was not found useful. Despite the challenges of conducting longitudinally designed studies with emerging adults, multiple retention strategies can be used that are useful to retention. It is feasible to conduct longitudinal studies with emerging adults despite the challenges.

A Primer on Longitudinal Data Analysis in Education. Technical Report #1320

ERIC Educational Resources Information Center

Nese, Joseph F. T.; Lai, Cheng-Fei; Anderson, Daniel

2013-01-01

Longitudinal data analysis in education is the study growth over time. A longitudinal study is one in which repeated observations of the same variables are recorded for the same individuals over a period of time. This type of research is known by many names (e.g., time series analysis or repeated measures design), each of which can imply subtle…

Spousal Interrelations in Happiness in the Seattle Longitudinal Study: Considerable Similarities in Levels and Change over Time

ERIC Educational Resources Information Center

Hoppmann, Christiane A.; Gerstorf, Denis; Willis, Sherry L.; Schaie, K. Warner

2011-01-01

Development does not take place in isolation and is often interrelated with close others such as marital partners. To examine interrelations in spousal happiness across midlife and old age, we used 35-year longitudinal data from both members of 178 married couples in the Seattle Longitudinal Study. Latent growth curve models revealed sizeable…

Future Orientation, Impulsivity, and Problem Behaviors: A Longitudinal Moderation Model

ERIC Educational Resources Information Center

Chen, Pan; Vazsonyi, Alexander T.

2011-01-01

In the current study, based on a sample of 1,873 adolescents between 11.4 and 20.9 years of age from the first 3 waves of the National Longitudinal Study of Adolescent Health, we investigated the longitudinal effects of future orientation on levels of and developmental changes in problem behaviors, while controlling for the effects by impulsivity;…

Recruitment Modeling Applied to Longitudinal Studies of Group Differences in Intelligence

ERIC Educational Resources Information Center

Madhyastha, Tara M.; Hunt, Earl; Deary, Ian J.; Gale, Catharine R.; Dykiert, Dominika

2009-01-01

In longitudinal studies data is collected in a series of waves. Each wave after the first suffers from attrition. Therefore it can be difficult to discriminate between changes in sample parameters due to a longitudinal process (e.g. ageing) and changes due to attrition. The problem is particularly vexing if one of the purposes is to compare…

What Alumni Value from New Product Development Education: A Longitudinal Study

ERIC Educational Resources Information Center

Cobb, Corie L.; Hey, Jonathan; Agogino, Alice M.; Beckman, Sara L.; Kim, Sohyeong

2016-01-01

We present a longitudinal study of what graduates take away from a cross-disciplinary graduate-level New Product Development (NPD) course at UC Berkeley over a 15-year period from 1996-2010. We designed and deployed a longitudinal survey and interviewed a segment of our NPD alumni population to better understand how well our course prepared these…

A Longitudinal Study of Midage Women with Indicators of Disordered Eating

ERIC Educational Resources Information Center

Fairweather-Schmidt, A. Kate; Lee, Christina; Wade, Tracey D.

2015-01-01

This longitudinal study of midage women has two main aims: to examine the effect of disordered eating (DE) on quality of life (QoL) among women, including a comparison with a younger cohort and to investigate the mediating roles of both depressive symptoms and social support on the longitudinal relationship between DE and QoL as potential…

Longitudinal Stability of the Beck Depression Inventory II: A Latent Trait-State-Occasion Model

ERIC Educational Resources Information Center

Wu, Pei-Chen

2016-01-01

In a six-wave longitudinal study with two cohorts (660 adolescents and 630 young adults), this study investigated the longitudinal stability of the Beck Depression Inventory II (BDI-II) using the Trait-State-Occasion (TSO) model. The results revealed that the full TSO model was the best fitting representation of the depression measured by the…

An air brake model for longitudinal train dynamics studies

NASA Astrophysics Data System (ADS)

Wei, Wei; Hu, Yang; Wu, Qing; Zhao, Xubao; Zhang, Jun; Zhang, Yuan

2017-04-01

Experience of heavy haul train operation shows that heavy haul train fatigue fracture of coupler and its related components, even the accidents are caused by excessive coupler force. The most economical and effective method to study on train longitudinal impulse by reducing the coupler force is simulation method. The characteristics of train air brake system is an important excitation source for the study of longitudinal impulse. It is very difficult to obtain the braking characteristic by the test method, a better way to get the input parameters of the excitation source in the train longitudinal dynamics is modelling the train air brake system. In this paper, the air brake system model of integrated system of air brake and longitudinal dynamics is introduced. This introduce is focus on the locomotive automatic brake valve and vehicle distribution valve model, and the comparative analysis of the simulation and test results of the braking system is given. It is proved that the model can predict the characteristics of train braking system. This method provides a good solution for the excitation source of longitudinal dynamic analysis system.

A Fast EM Algorithm for Fitting Joint Models of a Binary Response and Multiple Longitudinal Covariates Subject to Detection Limits

PubMed Central

Bernhardt, Paul W.; Zhang, Daowen; Wang, Huixia Judy

2014-01-01

Joint modeling techniques have become a popular strategy for studying the association between a response and one or more longitudinal covariates. Motivated by the GenIMS study, where it is of interest to model the event of survival using censored longitudinal biomarkers, a joint model is proposed for describing the relationship between a binary outcome and multiple longitudinal covariates subject to detection limits. A fast, approximate EM algorithm is developed that reduces the dimension of integration in the E-step of the algorithm to one, regardless of the number of random effects in the joint model. Numerical studies demonstrate that the proposed approximate EM algorithm leads to satisfactory parameter and variance estimates in situations with and without censoring on the longitudinal covariates. The approximate EM algorithm is applied to analyze the GenIMS data set. PMID:25598564

Early School Transitions and the Social Behavior of Children with Disabilities: Selected Findings from the Pre-Elementary Education Longitudinal Study. Wave 3 Overview Report from the Pre-Elementary Education Longitudinal Study (PEELS). NCSER 2009-3016

ERIC Educational Resources Information Center

Carlson, Elaine; Daley, Tamara; Bitterman, Amy; Heinzen, Harriotte; Keller, Brad; Markowitz, Joy; Riley, Jarnee

2009-01-01

The Pre-Elementary Education Longitudinal Study (PEELS), funded by the U.S. Department of Education, is examining the characteristics of children receiving preschool special education, the services they receive, their transitions across educational levels, and their performance over time on assessments of academic and adaptive skills. PEELS…

The Children Born in 2001 at Kindergarten Entry: First Findings from the Kindergarten Data Collections of the Early Childhood Longitudinal Study, Birth Cohort (ECLS-B). First Look. NCES 2010-005

ERIC Educational Resources Information Center

Flanagan, Kristin Denton; McPhee, Cameron

2009-01-01

Using data from the final two rounds of the Early Childhood Longitudinal Study, Birth Cohort (ECLS-B), a longitudinal study begun in 2001, this First Look provides a snapshot of the demographic characteristics, reading and mathematics knowledge, fine motor skills, school characteristics, and before- and after-school care arrangements of the cohort…

Presymptomatic and longitudinal neuroimaging in neurodegeneration--from snapshots to motion picture: a systematic review.

PubMed

Schuster, Christina; Elamin, Marwa; Hardiman, Orla; Bede, Peter

2015-10-01

Recent quantitative neuroimaging studies have been successful in capturing phenotype and genotype-specific changes in dementia syndromes, amyotrophic lateral sclerosis, Parkinson's disease and other neurodegenerative conditions. However, the majority of imaging studies are cross-sectional, despite the obvious superiority of longitudinal study designs in characterising disease trajectories, response to therapy, progression rates and evaluating the presymptomatic phase of neurodegenerative conditions. The aim of this work is to perform a systematic review of longitudinal imaging initiatives in neurodegeneration focusing on methodology, optimal statistical models, follow-up intervals, attrition rates, primary study outcomes and presymptomatic studies. Longitudinal imaging studies were identified from 'PubMed' and reviewed from 1990 to 2014. The search terms 'longitudinal', 'MRI', 'presymptomatic' and 'imaging' were utilised in combination with one of the following degenerative conditions; Alzheimer's disease, amyotrophic lateral sclerosis/motor neuron disease, frontotemporal dementia, Huntington's disease, multiple sclerosis, Parkinson's disease, ataxia, HIV, alcohol abuse/dependence. A total of 423 longitudinal imaging papers and 103 genotype-based presymptomatic studies were identified and systematically reviewed. Imaging techniques, follow-up intervals and attrition rates showed significant variation depending on the primary diagnosis. Commonly used statistical models included analysis of annualised percentage change, mixed and random effect models, and non-linear cumulative models with acceleration-deceleration components. Although longitudinal imaging studies have the potential to provide crucial insights into the presymptomatic phase and natural trajectory of neurodegenerative processes a standardised design is required to enable meaningful data interpretation. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Consistency between cross-sectional and longitudinal SNP: blood lipid associations.

PubMed

Costanza, Michael C; Beer-Borst, Sigrid; James, Richard W; Gaspoz, Jean-Michel; Morabia, Alfredo

2012-02-01

Various studies have linked different genetic single nucleotide polymorphisms (SNPs) to different blood lipids (BL), but whether these "connections" were identified using cross-sectional or longitudinal (i.e., changes over time) designs has received little attention. Cross-sectional and longitudinal assessments of BL [total, high-, low-density lipoprotein cholesterol (TC, HDL, LDL), triglycerides (TG)] and non-genetic factors (body mass index, smoking, alcohol intake) were measured for 2,002 Geneva, Switzerland, adults during 1999-2008 (two measurements, median 6 years apart), and 20 SNPs in 13 BL metabolism-related genes. Fixed and mixed effects repeated measures linear regression models, respectively, were employed to identify cross-sectional and longitudinal SNP:BL associations among the 1,516 (76%) study participants who reported not being treated for hypercholesterolemia at either measurement time. One-third more (12 vs. 9) longitudinal than cross-sectional associations were found [Bonferroni-adjusted two-tailed p < 0.00125 (=0.05/2)/20) for each of the four ensembles of 20 SNP:individual BL associations tested under the two study designs]. There was moderate consistency between the cross-sectional and longitudinal findings, with eight SNP:BL associations consistently identified across both study designs: [APOE.2 and APOE.4 (rs7412 and rs429358)]:TC; HL/LIPC (rs2070895):HDL; [APOB (rs1367117), APOE.2 and APOE.4 (rs7412 and rs429358)]:LDL; [APOA5 (rs2072560) and APOC III (rs5128)]:TG. The results suggest that cross-sectional studies, which include most genome-wide association studies (GWAS), can assess the large majority of SNP:BL associations. In the present analysis, which was much less powered than a GWAS, the cross-sectional study was around 2/3 (67%) as efficient as the longitudinal study.

Dimensions of integration, continuity and longitudinality in clinical clerkships.

PubMed

Ellaway, Rachel H; Graves, Lisa; Cummings, Beth-Ann

2016-09-01

Over the past few decades, longitudinal integrated clerkships (LICs) have been proposed to address many perceived short-coming of traditional block clerkships. This growing interest in LICs has raised broader questions regarding the role of integration, continuity and longitudinality in medical education. A study with complementary theoretical and empirical dimensions was conducted to derive a more precise way of defining these three underlying concepts within the design of medical education curricula. The theoretical dimension involved a thematic review of the literature on integration, continuity and longitudinality in medical education. The empirical dimension surveyed all 17 Canadian medical schools on how they have operationalised integration, continuity and longitudinality in their undergraduate programmes. The two dimensions were iteratively synthesised to explore the meaning and expression of integration, continuity and longitudinality in medical education curriculum design. Integration, continuity and longitudinality were expressed in many ways and forms, including: integration of clinical disciplines, combined horizontal integration and vertical integration, and programme-level integration. Types of continuity included: continuity of patients, continuity of teaching, continuity of location and peer continuity. Longitudinality focused on connected or repeating episodes of training or on connecting activities, such as encounter logging across educational episodes. Twelve of the 17 schools were running an LIC of some kind, although only one school had a mandatory LIC experience. An ordinal scale of uses of integration, continuity and longitudinality during clerkships was developed, and new definitions of these concepts in the clerkship context were generated. Different clerkship designs embodied different forms and levels of integration, continuity and longitudinality. A dichotomous view of LICs and rotation-based clerkships was found not to represent current practices in Canada, which instead tended to fall along a continuum of integration, continuity and longitudinality. © 2016 John Wiley & Sons Ltd and The Association for the Study of Medical Education.

African experiences of humanitarian cardiovascular medicine: the Cardiac Centre of St. Elizabeth Catholic General Hospital, Shisong.

PubMed

Budzee, Sr Appolonia; Tchoumi, Jc Tantchou; Giamberti, Alessandro; Ambassa, Jc; Cirri, Sylvia; Butera, Gianfranco

2012-06-01

The cardiac centre of Shisong inaugurated few years ago is a good example of the mobilization of humanitarian resources from the north and south for the improvement of cardiovascular diagnosis and treatment in Africa. From the inauguration of the Center to December 2011, 23 surgical missions have been organized, (5 peadiatric and 18 adults) and 204 patients have been operated with the help of the partners: Associazione Bambini Cardiopatici nel Mondo and Cuore Fratello. The Catheterisation Laboratory has performed a total of 117 diagnostic and interventional procedures while 22 pace makers were implanted (12 single-chambers and 10 dual-chambers). Many problems and challenges are faced everyday but with the enthusiasm, the dynamism and the professional skills of the personnel, the help of the partners we see a bright future.

African experiences of humanitarian cardiovascular medicine: the Cardiac Centre of St. Elizabeth Catholic General Hospital, Shisong

PubMed Central

Budzee, Sr. Appolonia; Giamberti, Alessandro; Ambassa, JC; Cirri, Sylvia; Butera, Gianfranco

2012-01-01

The cardiac centre of Shisong inaugurated few years ago is a good example of the mobilization of humanitarian resources from the north and south for the improvement of cardiovascular diagnosis and treatment in Africa. From the inauguration of the Center to December 2011, 23 surgical missions have been organized, (5 peadiatric and 18 adults) and 204 patients have been operated with the help of the partners: Associazione Bambini Cardiopatici nel Mondo and Cuore Fratello. The Catheterisation Laboratory has performed a total of 117 diagnostic and interventional procedures while 22 pace makers were implanted (12 single-chambers and 10 dual-chambers). Many problems and challenges are faced everyday but with the enthusiasm, the dynamism and the professional skills of the personnel, the help of the partners we see a bright future. PMID:24282709

Microcracking, microcrack-induced delamination, and longitudinal splitting of advanced composite structures

NASA Technical Reports Server (NTRS)

Nairn, John A.

1992-01-01

A combined analytical and experimental study was conducted to analyze microcracking, microcrack-induced delamination, and longitudinal splitting in polymer matrix composites. Strain energy release rates, calculated by a variational analysis, were used in a failure criterion to predict microcracking. Predictions and test results were compared for static, fatigue, and cyclic thermal loading. The longitudinal splitting analysis accounted for the effects of fiber bridging. Test data are analyzed and compared for longitudinal splitting and delamination under mixed-mode loading. This study emphasizes the importance of using fracture mechanics analyses to understand the complex failure processes that govern composite strength and life.

The Multigroup Multilevel Categorical Latent Growth Curve Models

ERIC Educational Resources Information Center

Hung, Lai-Fa

2010-01-01

Longitudinal data describe developmental patterns and enable predictions of individual changes beyond sampled time points. Major methodological issues in longitudinal data include modeling random effects, subject effects, growth curve parameters, and autoregressive residuals. This study embedded the longitudinal model within a multigroup…

Longitudinal Variations of Low-Latitude Gravity Waves and Their Impacts on the Ionosphere

NASA Astrophysics Data System (ADS)

Cullens, C. Y.; England, S.; Immel, T. J.

2014-12-01

The lower atmospheric forcing has important roles in the ionospheric variability. However, influences of lower atmospheric gravity waves on the ionospheric variability are still not clear due to the simplified gravity wave parameterizations and the limited knowledge of gravity wave distributions. In this study, we aim to study the longitudinal variations of gravity waves and their impacts of longitudinal variations of low-latitude gravity waves on the ionospheric variability. Our SABER results show that longitudinal variations of gravity waves at the lower boundary of TIME-GCM are the largest in June-August and January-February. We have implemented these low-latitude gravity wave variations from SABER instrument into TIME-GCM model. TIME-GCM simulation results of ionospheric responses to longitudinal variations of gravity waves and physical mechanisms will be discussed.

Nuestra culpa: collective guilt and shame as predictors of reparation for historical wrongdoing.

PubMed

Brown, Rupert; González, Roberto; Zagefka, Hanna; Manzi, Jorge; Cehajic, Sabina

2008-01-01

Three studies examined the hypothesis that collective guilt and shame have different consequences for reparation. In 2 longitudinal studies, the ingroup was nonindigenous Chileans (Study 1: N = 124/120, lag = 8 weeks; Study 2: N = 247/137, lag = 6 months), and the outgroup was Chile's largest indigenous group, the Mapuche. In both studies, it was found that collective guilt predicted reparation attitudes longitudinally. Collective shame had only cross-sectional associations with reparation and no direct longitudinal effects. In Study 2, collective shame moderated the longitudinal effects of collective guilt such that the effects of guilt were stronger for low-shame respondents. In Study 3 (N = 193 nonindigenous Chileans), the cross-sectional relationships among guilt, shame, and reparation attitudes were replicated. The relationship between shame and reparation attitudes was mediated by a desire to improve the ingroup's reputation. Copyright 2008 APA, all rights reserved.

Longitudinal design considerations to optimize power to detect variances and covariances among rates of change: Simulation results based on actual longitudinal studies

PubMed Central

Rast, Philippe; Hofer, Scott M.

2014-01-01

We investigated the power to detect variances and covariances in rates of change in the context of existing longitudinal studies using linear bivariate growth curve models. Power was estimated by means of Monte Carlo simulations. Our findings show that typical longitudinal study designs have substantial power to detect both variances and covariances among rates of change in a variety of cognitive, physical functioning, and mental health outcomes. We performed simulations to investigate the interplay among number and spacing of occasions, total duration of the study, effect size, and error variance on power and required sample size. The relation between growth rate reliability (GRR) and effect size to the sample size required to detect power ≥ .80 was non-linear, with rapidly decreasing sample sizes needed as GRR increases. The results presented here stand in contrast to previous simulation results and recommendations (Hertzog, Lindenberger, Ghisletta, & von Oertzen, 2006; Hertzog, von Oertzen, Ghisletta, & Lindenberger, 2008; von Oertzen, Ghisletta, & Lindenberger, 2010), which are limited due to confounds between study length and number of waves, error variance with GCR, and parameter values which are largely out of bounds of actual study values. Power to detect change is generally low in the early phases (i.e. first years) of longitudinal studies but can substantially increase if the design is optimized. We recommend additional assessments, including embedded intensive measurement designs, to improve power in the early phases of long-term longitudinal studies. PMID:24219544

Bayesian analysis of longitudinal dyadic data with informative missing data using a dyadic shared-parameter model.

PubMed

Ahn, Jaeil; Morita, Satoshi; Wang, Wenyi; Yuan, Ying

2017-01-01

Analyzing longitudinal dyadic data is a challenging task due to the complicated correlations from repeated measurements and within-dyad interdependence, as well as potentially informative (or non-ignorable) missing data. We propose a dyadic shared-parameter model to analyze longitudinal dyadic data with ordinal outcomes and informative intermittent missing data and dropouts. We model the longitudinal measurement process using a proportional odds model, which accommodates the within-dyad interdependence using the concept of the actor-partner interdependence effects, as well as dyad-specific random effects. We model informative dropouts and intermittent missing data using a transition model, which shares the same set of random effects as the longitudinal measurement model. We evaluate the performance of the proposed method through extensive simulation studies. As our approach relies on some untestable assumptions on the missing data mechanism, we perform sensitivity analyses to evaluate how the analysis results change when the missing data mechanism is misspecified. We demonstrate our method using a longitudinal dyadic study of metastatic breast cancer.

Psychosocial predictors of non-adherence to chronic medication: systematic review of longitudinal studies

PubMed Central

Zwikker, Hanneke E; van den Bemt, Bart J; Vriezekolk, Johanna E; van den Ende, Cornelia H; van Dulmen, Sandra

2014-01-01

Objectives Several cross-sectional studies suggest that psychosocial factors are associated with non-adherence to chronic preventive maintenance medication (CPMM); however, results from longitudinal associations have not yet been systematically summarized. Therefore, the objective of this study was to systematically synthesize evidence of longitudinal associations between psychosocial predictors and CPMM non-adherence. Materials and methods PUBMED, EMBASE, CINAHL, and PsychINFO databases were searched for studies meeting our inclusion criteria. The reference lists and the ISI Web of Knowledge of the included studies were checked. Studies were included if they had an English abstract, involved adult populations using CPMM living in Western countries, and if they investigated associations between psychosocial predictors and medication non-adherence using longitudinal designs. Data were extracted according to a literature-based extraction form. Study quality was independently judged by two researchers using a framework comprising six bias domains. Studies were considered to be of high quality if ≥four domains were free of bias. Psychosocial predictors for non-adherence were categorized into five pre-defined categories: beliefs/cognitions; coping styles; social influences and social support; personality traits; and psychosocial well-being. A qualitative best evidence synthesis was performed to synthesize evidence of longitudinal associations between psychosocial predictors and CPMM non-adherence. Results Of 4,732 initially-identified studies, 30 (low-quality) studies were included in the systematic review. The qualitative best evidence synthesis demonstrated limited evidence for absence of a longitudinal association between CPMM non-adherence and the psychosocial categories. The strength of evidence for the review’s findings is limited by the low quality of included studies. Conclusion The results do not provide psychosocial targets for the development of new interventions in clinical practice. This review clearly demonstrates the need for high-quality, longitudinal research to identify psychosocial predictors of medication non-adherence. PMID:24851043

A Longitudinal Study of Progress in Vocabulary Size of Japanese EFL Senior High School Learners: A Comparison of the General and Commercial Courses

ERIC Educational Resources Information Center

Akase, Masaki; Uenishi, Koji

2015-01-01

The purposes of this study are (1) to longitudinally measure the receptive vocabulary size (VS) of Japanese EFL senior high school learners; (2) to investigate how the learners develop their VS; and (3) to describe the longitudinal developmental patterns of VS of each learner during their three years of high school. Kasahara's (2005) VS tests, a…

Statistical Properties of Longitudinal Time-Activity Data for Use in Human Exposure Modeling

EPA Science Inventory

Understanding the longitudinal properties of the time spent in different locations and activities is important in characterizing human exposure to pollutants. The results of a four-season longitudinal time-activity diary study in eight working adults are presented, with the goal ...

Modeling Longitudinal Data Containing Non-Normal Within Subject Errors

NASA Technical Reports Server (NTRS)

Feiveson, Alan; Glenn, Nancy L.

2013-01-01

The mission of the National Aeronautics and Space Administration’s (NASA) human research program is to advance safe human spaceflight. This involves conducting experiments, collecting data, and analyzing data. The data are longitudinal and result from a relatively few number of subjects; typically 10 – 20. A longitudinal study refers to an investigation where participant outcomes and possibly treatments are collected at multiple follow-up times. Standard statistical designs such as mean regression with random effects and mixed–effects regression are inadequate for such data because the population is typically not approximately normally distributed. Hence, more advanced data analysis methods are necessary. This research focuses on four such methods for longitudinal data analysis: the recently proposed linear quantile mixed models (lqmm) by Geraci and Bottai (2013), quantile regression, multilevel mixed–effects linear regression, and robust regression. This research also provides computational algorithms for longitudinal data that scientists can directly use for human spaceflight and other longitudinal data applications, then presents statistical evidence that verifies which method is best for specific situations. This advances the study of longitudinal data in a broad range of applications including applications in the sciences, technology, engineering and mathematics fields.

Vibration Measurement on Reticular Lamina and Basilar Membrane at Multiple Longitudinal Locations

NASA Astrophysics Data System (ADS)

Chen, Fangyi; Zha, Dingjun; Choudhury, Niloy; Fridberger, Anders; Nuttall, Alfred L.

2011-11-01

The longitudinal distribution of the organ of Corti vibration is important for both understanding the energy delivery and the timing of the cochlear amplification. Recent development on low coherence interferomtry technique allows measuring vibration inside the cochlea. The reticular lamina (RL) vibration spectrum demonstrates that RL vibration leads the basilar membrane (BM). This phase lead is consistent with the idea that the active process may lead the BM vibration. In this study, measurements on multiple longitudinal locations demonstrated similar phase lead. Results on this study suggests that there may be another longitudinal coupling mechanism inside the cochlea other than the traveling wave on BM.

Longitudinal Effects of Embryonic Exposure to Cocaine on Morphology, Cardiovascular Physiology, and Behavior in Zebrafish.

PubMed

Mersereau, Eric J; Boyle, Cody A; Poitra, Shelby; Espinoza, Ana; Seiler, Joclyn; Longie, Robert; Delvo, Lisa; Szarkowski, Megan; Maliske, Joshua; Chalmers, Sarah; Darland, Diane C; Darland, Tristan

2016-05-31

A sizeable portion of the societal drain from cocaine abuse results from the complications of in utero drug exposure. Because of challenges in using humans and mammalian model organisms as test subjects, much debate remains about the impact of in utero cocaine exposure. Zebrafish offer a number of advantages as a model in longitudinal toxicology studies and are quite sensitive physiologically and behaviorally to cocaine. In this study, we have used zebrafish to model the effects of embryonic pre-exposure to cocaine on development and on subsequent cardiovascular physiology and cocaine-induced conditioned place preference (CPP) in longitudinal adults. Larval fish showed a progressive decrease in telencephalic size with increased doses of cocaine. These treated larvae also showed a dose dependent response in heart rate that persisted 24 h after drug cessation. Embryonic cocaine exposure had little effect on overall health of longitudinal adults, but subtle changes in cardiovascular physiology were seen including decreased sensitivity to isoproterenol and increased sensitivity to cocaine. These longitudinal adult fish also showed an embryonic dose-dependent change in CPP behavior, suggesting an increased sensitivity. These studies clearly show that pre-exposure during embryonic development affects subsequent cocaine sensitivity in longitudinal adults.

A longitudinal multilevel CFA-MTMM model for interchangeable and structurally different methods

PubMed Central

Koch, Tobias; Schultze, Martin; Eid, Michael; Geiser, Christian

2014-01-01

One of the key interests in the social sciences is the investigation of change and stability of a given attribute. Although numerous models have been proposed in the past for analyzing longitudinal data including multilevel and/or latent variable modeling approaches, only few modeling approaches have been developed for studying the construct validity in longitudinal multitrait-multimethod (MTMM) measurement designs. The aim of the present study was to extend the spectrum of current longitudinal modeling approaches for MTMM analysis. Specifically, a new longitudinal multilevel CFA-MTMM model for measurement designs with structurally different and interchangeable methods (called Latent-State-Combination-Of-Methods model, LS-COM) is presented. Interchangeable methods are methods that are randomly sampled from a set of equivalent methods (e.g., multiple student ratings for teaching quality), whereas structurally different methods are methods that cannot be easily replaced by one another (e.g., teacher, self-ratings, principle ratings). Results of a simulation study indicate that the parameters and standard errors in the LS-COM model are well recovered even in conditions with only five observations per estimated model parameter. The advantages and limitations of the LS-COM model relative to other longitudinal MTMM modeling approaches are discussed. PMID:24860515

Longitudinal Changes in Serum Glucose Levels are Associated with Metabolic Changes in Alzheimer's Disease Related Brain Regions.

PubMed

Burns, Christine M; Kaszniak, Alfred W; Chen, Kewei; Lee, Wendy; Bandy, Daniel J; Caselli, Richard J; Reiman, Eric M

2018-01-01

The association between longitudinal changes in serum glucose level and longitudinal changes in [18F] Fluorodeoxyglucose-PET (FDG PET) measurements of Alzheimer's disease (AD) risk are unknown. To investigate whether variation in serum glucose levels across time are associated with changes in FDG PET measurements of cerebral metabolic rate for glucose (rCMRgl) in brain regions preferentially affected by Alzheimer's disease (AD). Participants are a subset of a prospective cohort study investigating FDG PET, apolipoprotein E (APOE) ɛ4, and risk for AD which includes data from baseline, interim, and follow up visits over 4.4±1.0-years. An automated brain-mapping algorithm was utilized to characterize and compare associations between longitudinal changes in serum glucose levels and longitudinal changes in rCMRgl. This study included 80 adults aged 61.5±5 years, including 38 carriers and 42 non-carriers of the APOE ɛ4 allele. Longitudinal increases in serum glucose levels were associated with longitudinal CMRgl decline in the vicinity of parietotemporal, precuneus/posterior cingulate, and prefrontal brain regions preferentially affected by AD (p < 0.05, corrected for multiple comparisons). Findings remained significant when controlled for APOE ɛ4 status and baseline and advancing age. Additional studies are needed to clarify and confirm the relationship between longitudinal changes in peripheral glucose and FDG PET measurements of AD risk. Future findings will set the stage on the use of FDG PET in the evaluation of possible interventions that target risk factors for the development of AD.

The Longitudinal Interplay of Maternal Warmth and Adolescents' Self-Disclosure in Predicting Maternal Knowledge

ERIC Educational Resources Information Center

Blodgett Salafia, Elizabeth H.; Gondoli, Dawn M.; Grundy, Amber M.

2009-01-01

This study examined the longitudinal associations among maternal warmth, adolescents' self-disclosure, and maternal knowledge during the transition to adolescence. Three years of self-report data were collected from 131 married mothers and their adolescents. Results from longitudinal analysis using adolescent reports indicated that greater…

Longitudinal Research with Sexual Assault Survivors: A Methodological Review

ERIC Educational Resources Information Center

Campbell, Rebecca; Sprague, Heather Brown; Cottrill, Sara; Sullivan, Cris M.

2011-01-01

Longitudinal research designs are relatively rare in the academic literature on rape and sexual assault despite their tremendous methodological rigor and scientific utility. In the interest of promoting wider use of such methods, we conducted a methodological review of projects that have used prospective longitudinal designs to study the…

Modeling a Longitudinal Relational Research Data Systems

ERIC Educational Resources Information Center

Olsen, Michelle D. Hunt

2010-01-01

A study was conducted to propose a research-based model for a longitudinal data research system that addressed recommendations from a synthesis of literature related to: (1) needs reported by the U.S. Department of Education, (2) the twelve mandatory elements that define federally approved state longitudinal data systems (SLDS), (3) the…

Multivariate Longitudinal Methods for Studying Developmental Relationships between Depression and Academic Achievement

ERIC Educational Resources Information Center

Grimm, Kevin J.

2007-01-01

Recent advances in methods and computer software for longitudinal data analysis have pushed researchers to more critically examine developmental theories. In turn, researchers have also begun to push longitudinal methods by asking more complex developmental questions. One such question involves the relationships between two developmental…

Longitudinal Multistage Testing

ERIC Educational Resources Information Center

Pohl, Steffi

2013-01-01

This article introduces longitudinal multistage testing (lMST), a special form of multistage testing (MST), as a method for adaptive testing in longitudinal large-scale studies. In lMST designs, test forms of different difficulty levels are used, whereas the values on a pretest determine the routing to these test forms. Since lMST allows for…

Accounting for dropout reason in longitudinal studies with nonignorable dropout.

PubMed

Moore, Camille M; MaWhinney, Samantha; Forster, Jeri E; Carlson, Nichole E; Allshouse, Amanda; Wang, Xinshuo; Routy, Jean-Pierre; Conway, Brian; Connick, Elizabeth

2017-08-01

Dropout is a common problem in longitudinal cohort studies and clinical trials, often raising concerns of nonignorable dropout. Selection, frailty, and mixture models have been proposed to account for potentially nonignorable missingness by relating the longitudinal outcome to time of dropout. In addition, many longitudinal studies encounter multiple types of missing data or reasons for dropout, such as loss to follow-up, disease progression, treatment modifications and death. When clinically distinct dropout reasons are present, it may be preferable to control for both dropout reason and time to gain additional clinical insights. This may be especially interesting when the dropout reason and dropout times differ by the primary exposure variable. We extend a semi-parametric varying-coefficient method for nonignorable dropout to accommodate dropout reason. We apply our method to untreated HIV-infected subjects recruited to the Acute Infection and Early Disease Research Program HIV cohort and compare longitudinal CD4 + T cell count in injection drug users to nonusers with two dropout reasons: anti-retroviral treatment initiation and loss to follow-up.

A mechanical analysis of conduit arteries accounting for longitudinal residual strains.

PubMed

Wang, Ruoya; Gleason, Rudolph L

2010-04-01

Identification of an appropriate stress-free reference configuration is critically important in providing a reasonable prediction of the intramural stress distribution when performing biomechanical analyses on arteries. The stress-free state is commonly approximated as a radially cut ring that typically opens into a nearly circular sector, relieving much of the circumferential residual strains that exist in the traction-free configuration. An opening angle is often used to characterize this sector. In this study, we first present experimental results showing significant residual deformations in the longitudinal direction of two commonly studied arteries in the pig: the common carotid artery and the left anterior descending coronary artery. We concluded that a radially cut ring cannot completely describe the stress-free state of the arteries. Instead, we propose the use of a longitudinal opening angle, in conjunction with the traditional circumferential opening angle, to experimentally quantify the stress-free state of an artery. Secondly, we propose a new kinematic model to account for the addition of longitudinal residual strains through employing the longitudinal opening angle and performed a stress analysis. We found that with the inclusion of longitudinal residual strains in the stress analysis, the predicted circumferential stress gradient was decreased by 3-fold and the predicted longitudinal stress gradient was increased by 5.7-fold. Thus, inclusion of longitudinal residual strains has a significant effect on the predicted stress distribution in arteries.

The Impact of Motherhood on the Career Pattern of Working Women: Differences in the Life Histories and Career Status of Employed Mothers and Working Women without Children.

ERIC Educational Resources Information Center

Owings, Jeffrey A.; And Others

A study compared employed mothers with working women who do not have children along dimensions reflective of their life histories and labor market experiences. It utilized data from two nationwide longitudinal surveys--the National Longitudinal Survey of Young Women aged 14 to 24 and the National Longitudinal Study of the High School Class of…

Longitudinal Brain Magnetic Resonance Imaging CO2 Stress Testing in Individual Adolescent Sports-Related Concussion Patients: A Pilot Study.

PubMed

Mutch, W Alan C; Ellis, Michael J; Ryner, Lawrence N; Morissette, Marc P; Pries, Philip J; Dufault, Brenden; Essig, Marco; Mikulis, David J; Duffin, James; Fisher, Joseph A

2016-01-01

Advanced neuroimaging studies in concussion have been limited to detecting group differences between concussion patients and healthy controls. In this small pilot study, we used brain magnetic resonance imaging (MRI) CO2 stress testing to longitudinally assess cerebrovascular responsiveness (CVR) in individual sports-related concussion (SRC) patients. Six SRC patients (three males and three females; mean age = 15.7, range = 15-17 years) underwent longitudinal brain MRI CO2 stress testing using blood oxygen level-dependent (BOLD) MRI and model-based prospective end-tidal CO2 targeting under isoxic conditions. First-level and second-level comparisons were undertaken using statistical parametric mapping (SPM) to score the scans and compare them to an atlas of 24 healthy control subjects. All tests were well tolerated and without any serious adverse events. Anatomical MRI was normal in all study participants. The CO2 stimulus was consistent between the SRC patients and control subjects and within SRC patients across the longitudinal study. Individual SRC patients demonstrated both quantitative and qualitative patient-specific alterations in CVR (p < 0.005) that correlated strongly with clinical findings, and that persisted beyond clinical recovery. Standardized brain MRI CO2 stress testing is capable of providing a longitudinal assessment of CVR in individual SRC patients. Consequently, larger prospective studies are needed to examine the utility of brain MRI CO2 stress testing as a clinical tool to help guide the evaluation, classification, and longitudinal management of SRC patients.

Configurations of high-frequency ultrasonics complex vibration systems for packaging in microelectronics.

PubMed

Tsujino, Jiromaru; Harada, Yoshiki; Ihara, Shigeru; Kasahara, Kohei; Shimizu, Masanori; Ueoka, Tetsugi

2004-04-01

Ultrasonic high-frequency complex vibrations are effective for various ultrasonic high-power applications. Three types of ultrasonic complex vibration system with a welding tip vibrating elliptical to circular locus for packaging in microelectronics were studied. The complex vibration sources are using (1) a longitudinal-torsional vibration converter with diagonal slits that is driven only by a longitudinal vibration source, (2) a complex transverse vibration rod with several stepped parts that is driven by two longitudinal vibration source crossed at a right angle and (3) a longitudinal vibration circular disk and three longitudinal transducers that are installed at the circumference of the disk.

Multiple Kernel Learning with Random Effects for Predicting Longitudinal Outcomes and Data Integration

PubMed Central

Chen, Tianle; Zeng, Donglin

2015-01-01

Summary Predicting disease risk and progression is one of the main goals in many clinical research studies. Cohort studies on the natural history and etiology of chronic diseases span years and data are collected at multiple visits. Although kernel-based statistical learning methods are proven to be powerful for a wide range of disease prediction problems, these methods are only well studied for independent data but not for longitudinal data. It is thus important to develop time-sensitive prediction rules that make use of the longitudinal nature of the data. In this paper, we develop a novel statistical learning method for longitudinal data by introducing subject-specific short-term and long-term latent effects through a designed kernel to account for within-subject correlation of longitudinal measurements. Since the presence of multiple sources of data is increasingly common, we embed our method in a multiple kernel learning framework and propose a regularized multiple kernel statistical learning with random effects to construct effective nonparametric prediction rules. Our method allows easy integration of various heterogeneous data sources and takes advantage of correlation among longitudinal measures to increase prediction power. We use different kernels for each data source taking advantage of the distinctive feature of each data modality, and then optimally combine data across modalities. We apply the developed methods to two large epidemiological studies, one on Huntington's disease and the other on Alzheimer's Disease (Alzheimer's Disease Neuroimaging Initiative, ADNI) where we explore a unique opportunity to combine imaging and genetic data to study prediction of mild cognitive impairment, and show a substantial gain in performance while accounting for the longitudinal aspect of the data. PMID:26177419

Application of pattern mixture models to address missing data in longitudinal data analysis using SPSS.

PubMed

Son, Heesook; Friedmann, Erika; Thomas, Sue A

2012-01-01

Longitudinal studies are used in nursing research to examine changes over time in health indicators. Traditional approaches to longitudinal analysis of means, such as analysis of variance with repeated measures, are limited to analyzing complete cases. This limitation can lead to biased results due to withdrawal or data omission bias or to imputation of missing data, which can lead to bias toward the null if data are not missing completely at random. Pattern mixture models are useful to evaluate the informativeness of missing data and to adjust linear mixed model (LMM) analyses if missing data are informative. The aim of this study was to provide an example of statistical procedures for applying a pattern mixture model to evaluate the informativeness of missing data and conduct analyses of data with informative missingness in longitudinal studies using SPSS. The data set from the Patients' and Families' Psychological Response to Home Automated External Defibrillator Trial was used as an example to examine informativeness of missing data with pattern mixture models and to use a missing data pattern in analysis of longitudinal data. Prevention of withdrawal bias, omitted data bias, and bias toward the null in longitudinal LMMs requires the assessment of the informativeness of the occurrence of missing data. Missing data patterns can be incorporated as fixed effects into LMMs to evaluate the contribution of the presence of informative missingness to and control for the effects of missingness on outcomes. Pattern mixture models are a useful method to address the presence and effect of informative missingness in longitudinal studies.

Higher education affects accelerated cortical thinning in Alzheimer's disease: a 5-year preliminary longitudinal study.

PubMed

Cho, Hanna; Jeon, Seun; Kim, Changsoo; Ye, Byoung Seok; Kim, Geon Ha; Noh, Young; Kim, Hee Jin; Yoon, Cindy W; Kim, Yeo Jin; Kim, Jung-Hyun; Park, Sang Eon; Kim, Sung Tae; Lee, Jong-Min; Kang, Sue J; Suh, Mee Kyung; Chin, Juhee; Na, Duk L; Kang, Dae Ryong; Seo, Sang Won

2015-01-01

Epidemiological studies have reported that higher education (HE) is associated with a reduced risk of incident Alzheimer's disease (AD). However, after the clinical onset of AD, patients with HE levels show more rapid cognitive decline than patients with lower education (LE) levels. Although education level and cognition have been linked, there have been few longitudinal studies investigating the relationship between education level and cortical decline in patients with AD. The aim of this study was to compare the topography of cortical atrophy longitudinally between AD patients with HE (HE-AD) and AD patients with LE (LE-AD). We prospectively recruited 36 patients with early-stage AD and 14 normal controls. The patients were classified into two groups according to educational level, 23 HE-AD (>9 years) and 13 LE-AD (≤9 years). As AD progressed over the 5-year longitudinal follow-ups, the HE-AD showed a significant group-by-time interaction in the right dorsolateral frontal and precuneus, and the left parahippocampal regions compared to the LE-AD. Our study reveals that the preliminary longitudinal effect of HE accelerates cortical atrophy in AD patients over time, which underlines the importance of education level for predicting prognosis.

A Study of Learning Strategies in Foreign Language Instruction: Findings of the Longitudinal Study.

ERIC Educational Resources Information Center

Chamot, Anna Uhl; And Others

Part of a larger research project, this longitudinal study analyzed differences between effective and ineffective high school and college language learners and changes in strategy uses over time. Related studies include a descriptive study, which identified learning strategies used in studying foreign languages, and a course development study, in…

Longitudinal bunch monitoring at the Fermilab Tevatron and Main Injector synchrotrons

DOE PAGES

Thurman-Keup, R.; Bhat, C.; Blokland, W.; ...

2011-10-17

The measurement of the longitudinal behavior of the accelerated particle beams at Fermilab is crucial to the optimization and control of the beam and the maximizing of the integrated luminosity for the particle physics experiments. Longitudinal measurements in the Tevatron and Main Injector synchrotrons are based on the analysis of signals from resistive wall current monitors. This study describes the signal processing performed by a 2 GHz-bandwidth oscilloscope together with a computer running a LabVIEW program which calculates the longitudinal beam parameters.

Peer Influence and Nonsuicidal Self Injury: Longitudinal Results in Community and Clinically-Referred Adolescent Samples

ERIC Educational Resources Information Center

Prinstein, Mitchell J.; Heilbron, Nicole; Guerry, John D.; Franklin, Joseph C.; Rancourt, Diana; Simon, Valerie; Spirito, Anthony

2010-01-01

Research suggests that adolescents' engagement in nonsuicidal self-injurious (NSSI) behaviors may be increasing over time, yet little is known regarding distal longitudinal factors that may promote engagement in these behaviors. Data from two longitudinal studies are presented to examine whether NSSI may be associated with peer influence…

Mathematics Anxiety in Young Children: Concurrent and Longitudinal Associations with Mathematical Performance

ERIC Educational Resources Information Center

Vukovic, Rose K.; Kieffer, Michael J.; Bailey, Sean P.; Harari, Rachel R.

2013-01-01

This study explored mathematics anxiety in a longitudinal sample of 113 children followed from second to third grade. We examined how mathematics anxiety related to different types of mathematical performance concurrently and longitudinally and whether the relations between mathematics anxiety and mathematical performance differed as a function of…

Longitudinal Predictors of Chinese Word Reading and Spelling among Elementary Grade Students

ERIC Educational Resources Information Center

Yeung, Pui-Sze; Ho, Connie Suk-Han; Wong, Yau-Kai; Chung, Kevin Kien-Hoa; Lo, Lap-Yan

2013-01-01

The longitudinal predictive power of four important reading-related skills (phonological skills, rapid naming, orthographic skills, and morphological awareness) to Chinese word reading and writing to dictation (i.e., spelling) was examined in a 3-year longitudinal study among 251 Chinese elementary students. Rapid naming, orthographic skills, and…

Parental Involvement, Parenting Behaviors, and Children's Cognitive Development in Low-Income and Minority Families

ERIC Educational Resources Information Center

Chang, Mido; Park, Boyoung; Singh, Kusum; Sung, Youngji Y.

2009-01-01

The study examined the longitudinal association of parental involvement in Head Start parent-focused programs, parenting behaviors, and the cognitive development of children by specifying two longitudinal growth models. Model 1 examined the longitudinal effects of the parental involvement in three Head Start parenting programs (parenting classes,…

Applying the Nominal Response Model within a Longitudinal Framework to Construct the Positive Family Relationships Scale

ERIC Educational Resources Information Center

Preston, Kathleen Suzanne Johnson; Parral, Skye N.; Gottfried, Allen W.; Oliver, Pamella H.; Gottfried, Adele Eskeles; Ibrahim, Sirena M.; Delany, Danielle

2015-01-01

A psychometric analysis was conducted using the nominal response model under the item response theory framework to construct the Positive Family Relationships scale. Using data from the Fullerton Longitudinal Study, this scale was constructed within a long-term longitudinal framework spanning middle childhood through adolescence. Items tapping…

Longitudinal Relations between Peer Victimization, Emotion Dysregulation, and Internalizing Symptoms among Early Adolescents

ERIC Educational Resources Information Center

Doyle, Sarah T.; Sullivan, Terri N.

2017-01-01

The current study examined longitudinal relations between overt and relational victimization, sadness and anger dysregulation, and depressive and anxiety symptoms across 6 months among an ethnically diverse sample of sixth graders (N = 485; 48% male; 65% African American). No direct longitudinal relations were found between peer victimization and…

Which language declines more? longitudinal versus cross-sectional decline of picture naming in bilinguals with Alzheimer's disease.

PubMed

Ivanova, Iva; Salmon, David P; Gollan, Tamar H

2014-05-01

In this study, we investigated dual-language decline in non-balanced bilinguals with probable Alzheimer's disease (AD) both longitudinally and cross-sectionally. We examined patients' naming accuracy on the Boston Naming Test (BNT: Kaplan et al., 1983) over three testing sessions (longitudinal analysis) and compared their performance to that of matched controls (cross-sectional analysis). We found different longitudinal and cross-sectional patterns of decline: Longitudinally, the non-dominant language seemed to decline more steeply than the dominant language, but, cross-sectionally, differences between patients and controls were larger for the dominant than for the non-dominant language, especially at the initial testing session. This differential pattern of results for cross-sectional versus longitudinal decline was supported by correlations between decline measures and BNT item characteristics. Further studies will be needed to better characterize the nature of linguistic decline in bilinguals with AD; however, these results suggest that representational robustness of individual lexical representations, rather than language membership, might determine the time course of decline for naming in bilinguals with AD.

Bayesian Covariate Selection in Mixed-Effects Models For Longitudinal Shape Analysis

PubMed Central

Muralidharan, Prasanna; Fishbaugh, James; Kim, Eun Young; Johnson, Hans J.; Paulsen, Jane S.; Gerig, Guido; Fletcher, P. Thomas

2016-01-01

The goal of longitudinal shape analysis is to understand how anatomical shape changes over time, in response to biological processes, including growth, aging, or disease. In many imaging studies, it is also critical to understand how these shape changes are affected by other factors, such as sex, disease diagnosis, IQ, etc. Current approaches to longitudinal shape analysis have focused on modeling age-related shape changes, but have not included the ability to handle covariates. In this paper, we present a novel Bayesian mixed-effects shape model that incorporates simultaneous relationships between longitudinal shape data and multiple predictors or covariates to the model. Moreover, we place an Automatic Relevance Determination (ARD) prior on the parameters, that lets us automatically select which covariates are most relevant to the model based on observed data. We evaluate our proposed model and inference procedure on a longitudinal study of Huntington's disease from PREDICT-HD. We first show the utility of the ARD prior for model selection in a univariate modeling of striatal volume, and next we apply the full high-dimensional longitudinal shape model to putamen shapes. PMID:28090246

Returning findings within longitudinal cohort studies: the 1958 birth cohort as an exemplar.

PubMed

Wallace, Susan E; Walker, Neil M; Elliott, Jane

2014-01-01

Population-based, prospective longitudinal cohort studies are considering the issues surrounding returning findings to individuals as a result of genomic and other medical research studies. While guidance is being developed for clinical settings, the process is less clear for those conducting longitudinal research. This paper discusses work conducted on behalf of The UK Cohort and Longitudinal Study Enhancement Resource programme (CLOSER) to examine consent requirements, process considerations and specific examples of potential findings in the context of the 1958 British Birth cohort. Beyond deciding which findings to return, there are questions of whether re-consent is needed and the possible impact on the study, how the feedback process will be managed, and what resources are needed to support that process. Recommendations are made for actions a cohort study should consider taking when making vital decisions regarding returning findings. Any decisions need to be context-specific, arrived at transparently, communicated clearly, and in the best interests of both the participants and the study.

Neuromapping: Inflight Evaluation of Cognition and Adaptability

NASA Technical Reports Server (NTRS)

Kofman, I. S.; De Dios, Y. E.; Lawrence, K.; Schade, A.; Reschke, M. F.; Bloomberg, J. J.; Wood, S. J.; Mulavara, A. P.; Seidle, R. D.

2016-01-01

In consideration of the health and performance of crewmembers during flight and postflight, we are conducting a controlled prospective longitudinal study to investigate the effects of spaceflight on the extent, longevity and neural bases of sensorimotor, cognitive, and neural changes. Previous studies investigating sensorimotor adaptation to the microgravity environment longitudinally inflight have shown reduction in the ability to perform complex dual tasks. In this study we perform a series of tests investigating the longitudinal effects of adaptation to the microgravity environment and how it affects spatial cognition, manual visuo-motor adaption and dual tasking.

Early Childhood Longitudinal Study, Kindergarten Class of 2010-11 (ECLS-K:2011): User's Manual for the ECLS-K:2011 Kindergarten-Second Grade Data File and Electronic Codebook, Public Version. NCES 2017-285

ERIC Educational Resources Information Center

Tourangeau, Karen; Nord, Christine; Lê, Thanh; Wallner-Allen, Kathleen; Vaden-Kiernan, Nancy; Blaker, Lisa; Najarian, Michelle

2017-01-01

This manual provides guidance and documentation for users of the longitudinal kindergarten-second grade (K-2) data file of the Early Childhood Longitudinal Study, Kindergarten Class of 2010-11 (ECLS-K:2011). It mainly provides information specific to the second-grade rounds of data collection. Users should refer to the "Early Childhood…

Early Childhood Longitudinal Study, Kindergarten Class of 2010-11 (ECLS-K:2011): User's Manual for the ECLS-K:2011 Kindergarten-Fourth Grade Data File and Electronic Codebook, Public Version. NCES 2018-032

ERIC Educational Resources Information Center

Tourangeau, Karen; Nord, Christine; Lê, Thanh; Wallner-Allen, Kathleen; Vaden-Kiernan, Nancy; Blaker, Lisa; Najarian, Michelle

2018-01-01

This manual provides guidance and documentation for users of the longitudinal kindergarten-fourth grade (K-4) data file of the Early Childhood Longitudinal Study, Kindergarten Class of 2010-11 (ECLS-K:2011). It mainly provides information specific to the fourth-grade round of data collection. The first chapter provides an overview of the…

Pre-Service Teachers' Beliefs about Language Teaching and Learning: A Longitudinal Study (Creencias de profesores principiantes acerca de la enseñanza y aprendizaje de lengua: un estudio longitudinal)

ERIC Educational Resources Information Center

Cota Grijalva, Sofía D.; Ruiz-Esparza Barajas, Elizabeth

2013-01-01

This paper contains the description of a research project that was carried out in the Bachelor of Arts in English Language Teaching program at a Mexican university. The study was longitudinal and it tracked fourteen students for four semesters of the eight semester program. The aim was to identify pre-service teachers' beliefs about English…

[Trattamento farmacologico del disturbo da uso di alcol. Evidenze scientifiche].

PubMed

Attilia, Fabio; Perciballi, Roberta; Rotondo, Claudia; Capriglione, Ida; Iannuzzi, Silvia; Attilia, Maria Luisa; Vitali, Mario; Alessandrini, Giovanni; Scamporrino, Maria Concetta Marcella; Fiore, Marco; Ceccanti, Mauro

2018-01-01

RIASSUNTO. La terapia farmacologica nei pazienti con disturbo da uso di alcol riveste un ruolo centrale nel progetto terapeutico, altamente contestualizzato in un approccio multidisciplinare. Sebbene i trattamenti non farmacologici per la dipendenza da alcol risultino ben strutturati e in continua evoluzione, dal punto di vista medico le possibilità di intervento sono realmente ristrette, con poche molecole a disposizione approvate per il disturbo da uso di alcol: nello specifico, l'acamprostato, il naltrexone e, più recentemente, il nalmefene tra gli anticraving; il disulfiram tra gli avversivanti. Nuovi approcci sperimentali stanno cercando di ampliare tale gamma attraverso l'utilizzo di farmaci off-label. Evidenze scientifiche devono supportare l'indicazione terapeutica, quest'ultima deve dimostrarsi "cucita" sulle esigenze del paziente e sulle comorbilità presenti tenendo conto del profilo bio-psico-sociale individuale. Fondamentale risulta il follow-up per valutare la ritenzione in trattamento e il monitoraggio degli outcome alcologici.

The South African Personality Inventory (SAPI): a culture-informed instrument for the country's main ethnocultural groups.

PubMed

Fetvadjiev, Velichko H; Meiring, Deon; van de Vijver, Fons J R; Nel, J Alewyn; Hill, Carin

2015-09-01

We present the development and the underlying structure of a personality inventory for the main ethnocultural groups of South Africa, using an emic-etic approach. The South African Personality Inventory (SAPI) was developed based on an extensive qualitative study of the implicit personality conceptions in the country's 11 official languages (Nel et al., 2012). Items were generated and selected (to a final set of 146) with a continuous focus on cultural adequacy and translatability. Students and community adults (671 Blacks, 198 Coloreds, 104 Indians, and 391 Whites) completed the inventory. A 6-dimensional structure (comprising a positive and a negative Social-Relational factor, Neuroticism, Extraversion, Conscientiousness, and Openness) was equivalent across groups and replicated in an independent sample of 139 Black and 270 White students. The SAPI correlated highly overall with impression-management aspects, but lower with lying aspects of social desirability. The SAPI social-relational factors were distinguishable from the Big Five in a joint factor analysis; the multiple correlations with the Big Five were .64 (positive) and .51 (negative social-relational). Implications and suggestions for emic-etic instrument and model development are discussed. (c) 2015 APA, all rights reserved.

Associations between aging-related changes in grip strength and cognitive function in older adults: A systematic review.

PubMed

Zammit, Andrea R; Robitaille, Annie; Piccinin, Andrea; Muniz-Terrera, Graciela; Hofer, Scott M

2018-03-08

Grip strength and cognitive function reflect upper body muscle strength and mental capacities. Cross-sectional research has suggested that in old age these two processes are moderately to highly associated, and that an underlying common cause drives this association. Our aim was to synthesize and evaluate longitudinal research addressing whether changes in grip strength are associated with changes in cognitive function in healthy older adults. We systematically reviewed English-language research investigating the longitudinal association between repeated measures of grip strength and of cognitive function in community-dwelling older adults to evaluate the extent to which the two indices decline concurrently. We used four search engines: Embase, PsychINFO, PubMed, and Web of Science. Of 459 unique citations, 6 met our full criteria: 4 studies reported a longitudinal association between rates of change in grip strength and cognitive function in older adults, 2 of which reported the magnitudes of these associations as ranging from low to moderate; 2 studies reported significant cross-sectional but not longitudinal associations among rates of change. All studies concluded that cognitive function and grip strength declined, on average, with increasing age, although with little to no evidence for longitudinal associations among rates of change. Future research is urged to expand the study of physical and cognitive associations in old age using a within-person and multi-study integrative approach to evaluate the reliability of longitudinal results with greater emphasis on the magnitude of this association.

Longitudinal muscle dysfunction in achalasia esophagus and its relevance.

PubMed

Mittal, Ravinder K; Hong, Su Jin; Bhargava, Valmik

2013-04-01

Muscularis propria of the esophagus is organized into circular and longitudinal muscle layers. Goal of this review is to summarize the role of longitudinal muscle in physiology and pathophysiology of esophageal sensory and motor function. Simultaneous manometry and ultrasound imaging that measure circular and longitudinal muscle contraction respectively reveal that during peristalsis 2 layers of the esophagus contract in perfect synchrony. On the other hand, during transient relaxation of the lower esophageal sphincter (LES), longitudinal muscle contracts independently of circular muscle. Recent studies provide novel insights, i.e., longitudinal muscle contraction of the esophagus induces LES relaxation and possibly descending relaxation of the esophagus. In achalasia esophagus and other motility disorders there is discoordination between the 2 muscle layers. Longitudinal muscle contraction patterns are different in the recently described three types of achalasia identified by high-resolution manometry. Robust contraction of the longitudinal muscle in type II achalasia causes pan-esophageal pressurization and is the mechanism of whatever little esophageal emptying that take place in the absence of peristalsis and impaired LES relaxation. It may be that preserved longitudinal muscle contraction is also the reason for superior outcome to medical/surgical therapy in type II achalasia esophagus. Prolonged contractions of longitudinal muscles of the esophagus is a possible mechanism of heartburn and "angina like" pain seen in esophageal motility disorders and possibly achalasia esophagus. Novel techniques to record longitudinal muscle contraction are on the horizon. Neuro-pharmacologic control of circular and longitudinal muscles is different, which provides an important opportunity for the development of novel pharmacological therapies to treat sensory and motor disorders of the esophagus.

Longitudinal Muscle Dysfunction in Achalasia Esophagus and Its Relevance

PubMed Central

Hong, Su Jin; Bhargava, Valmik

2013-01-01

Muscularis propria of the esophagus is organized into circular and longitudinal muscle layers. Goal of this review is to summarize the role of longitudinal muscle in physiology and pathophysiology of esophageal sensory and motor function. Simultaneous manometry and ultrasound imaging that measure circular and longitudinal muscle contraction respectively reveal that during peristalsis 2 layers of the esophagus contract in perfect synchrony. On the other hand, during transient relaxation of the lower esophageal sphincter (LES), longitudinal muscle contracts independently of circular muscle. Recent studies provide novel insights, i.e., longitudinal muscle contraction of the esophagus induces LES relaxation and possibly descending relaxation of the esophagus. In achalasia esophagus and other motility disorders there is discoordination between the 2 muscle layers. Longitudinal muscle contraction patterns are different in the recently described three types of achalasia identified by high-resolution manometry. Robust contraction of the longitudinal muscle in type II achalasia causes pan-esophageal pressurization and is the mechanism of whatever little esophageal emptying that take place in the absence of peristalsis and impaired LES relaxation. It may be that preserved longitudinal muscle contraction is also the reason for superior outcome to medical/surgical therapy in type II achalasia esophagus. Prolonged contractions of longitudinal muscles of the esophagus is a possible mechanism of heartburn and "angina like" pain seen in esophageal motility disorders and possibly achalasia esophagus. Novel techniques to record longitudinal muscle contraction are on the horizon. Neuro-pharmacologic control of circular and longitudinal muscles is different, which provides an important opportunity for the development of novel pharmacological therapies to treat sensory and motor disorders of the esophagus. PMID:23667744

LIFESPAN: A tool for the computer-aided design of longitudinal studies

PubMed Central

Brandmaier, Andreas M.; von Oertzen, Timo; Ghisletta, Paolo; Hertzog, Christopher; Lindenberger, Ulman

2015-01-01

Researchers planning a longitudinal study typically search, more or less informally, a multivariate space of possible study designs that include dimensions such as the hypothesized true variance in change, indicator reliability, the number and spacing of measurement occasions, total study time, and sample size. The main search goal is to select a research design that best addresses the guiding questions and hypotheses of the planned study while heeding applicable external conditions and constraints, including time, money, feasibility, and ethical considerations. Because longitudinal study selection ultimately requires optimization under constraints, it is amenable to the general operating principles of optimization in computer-aided design. Based on power equivalence theory (MacCallum et al., 2010; von Oertzen, 2010), we propose a computational framework to promote more systematic searches within the study design space. Starting with an initial design, the proposed framework generates a set of alternative models with equal statistical power to detect hypothesized effects, and delineates trade-off relations among relevant parameters, such as total study time and the number of measurement occasions. We present LIFESPAN (Longitudinal Interactive Front End Study Planner), which implements this framework. LIFESPAN boosts the efficiency, breadth, and precision of the search for optimal longitudinal designs. Its initial version, which is freely available at http://www.brandmaier.de/lifespan, is geared toward the power to detect variance in change as specified in a linear latent growth curve model. PMID:25852596

The effect of ball impact location on racket and forearm joint angle changes for one-handed tennis backhand groundstrokes.

PubMed

King, Mark; Hau, Agnes; Blenkinsop, Glen

2017-07-01

Recreational tennis players tend to have higher incidence of tennis elbow, and this has been hypothesised to be related to one-handed backhand technique and off-centre ball impacts on the racket face. This study aimed to investigate for a range of participants the effect of off-longitudinal axis and off-lateral axis ball-racket impact locations on racket and forearm joint angle changes immediately following impact in one-handed tennis backhand groundstrokes. Three-dimensional racket and wrist angular kinematic data were recorded for 14 university tennis players each performing 30 "flat" one-handed backhand groundstrokes. Off-longitudinal axis ball-racket impact locations explained over 70% of the variation in racket rotation about the longitudinal axis and wrist flexion/extension angles during the 30 ms immediately following impact. Off-lateral axis ball-racket impact locations had a less clear cut influence on racket and forearm rotations. Specifically off-longitudinal impacts below the longitudinal axis forced the wrist into flexion for all participants with there being between 11° and 32° of forced wrist flexion for an off-longitudinal axis impact that was 1 ball diameter away from the midline. This study has confirmed that off-longitudinal impacts below the longitudinal axis contribute to forced wrist flexion and eccentric stretch of the wrist extensors and there can be large differences in the amount of forced wrist flexion from individual to individual and between strokes with different impact locations.

Correlation between longitudinal, circumferential, and radial moduli in cortical bone: effect of mineral content.

PubMed

Macione, J; Depaula, C A; Guzelsu, N; Kotha, S P

2010-07-01

Previous studies indicate that changes in the longitudinal elastic properties of bone due to changes in mineral content are related to the longitudinal strength of bone tissue. Changes in mineral content are expected to affect bone tissue mechanical properties along all directions, albeit to different extents. However, changes in tissue mechanical properties along the different directions are expected to be correlated to one another. In this study, we investigate if radial, circumferential, and longitudinal moduli are related in bone tissue with varying mineral content. Plexiform bovine femoral bone samples were treated in fluoride ion solutions for a period of 3 and 12 days to obtain bones with 20% and 32% lower effective mineral contents. Transmission ultrasound velocities were obtained in the radial, circumferential, and longitudinal axes of bone and combined with measured densities to obtain corresponding tensorial moduli. Results indicate that moduli decreased with fluoride ion treatments and were significantly correlated to one another (r(2) radial vs. longitudinal = 0.80, r(2) circumferential vs. longitudinal = 0.90, r(2) radial vs. circumferential = 0.85). Densities calculated from using ultrasound parameters, acoustic impedance and transmission velocities, were moderately correlated to those measured by the Archimedes principle (r(2)=0.54, p<0.01). These results suggest that radial and circumferential ultrasound measurements could be used to determine the longitudinal properties of bone and that ultrasound may not be able to predict in vitro densities of bones containing unbonded mineral. Published by Elsevier Ltd.

Education does not slow cognitive decline with aging: 12-year evidence from the victoria longitudinal study.

PubMed

Zahodne, Laura B; Glymour, M Maria; Sparks, Catharine; Bontempo, Daniel; Dixon, Roger A; MacDonald, Stuart W S; Manly, Jennifer J

2011-11-01

Although the relationship between education and cognitive status is well-known, evidence regarding whether education moderates the trajectory of cognitive change in late life is conflicting. Early studies suggested that higher levels of education attenuate cognitive decline. More recent studies using improved longitudinal methods have not found that education moderates decline. Fewer studies have explored whether education exerts different effects on longitudinal changes within different cognitive domains. In the present study, we analyzed data from 1014 participants in the Victoria Longitudinal Study to examine the effects of education on composite scores reflecting verbal processing speed, working memory, verbal fluency, and verbal episodic memory. Using linear growth models adjusted for age at enrollment (range, 54-95 years) and gender, we found that years of education (range, 6-20 years) was strongly related to cognitive level in all domains, particularly verbal fluency. However, education was not related to rates of change over time for any cognitive domain. Results were similar in individuals older or younger than 70 at baseline, and when education was dichotomized to reflect high or low attainment. In this large longitudinal cohort, education was related to cognitive performance but unrelated to cognitive decline, supporting the hypothesis of passive cognitive reserve with aging.

Beginning Postsecondary Students Longitudinal Study: 1996-2001 (BPS:1996/2001) Methodology Report.

ERIC Educational Resources Information Center

Wine, Jennifer S.; Heuer, Ruth E.; Wheeless, Sara C.; Francis, Talbric L.; Franklin, Jeff W.; Dudley, Kristin M.

2002-01-01

Describes the procedures and results of the full-scale Implementation of the final followup interview with the Beginning Postsecondary Students Longitudinal Study 1996/2001. This study follows a cohort first interviewed in 1996 in their first year of postsecondary education. (SLD)

Suprasegmental Phonology Development and Reading Acquisition: A Longitudinal Study

ERIC Educational Resources Information Center

Calet, Nuria; Gutiérrez-Palma, Nicolás; Simpson, Ian C.; González-Trujillo, M. Carmen; Defior, Sylvia

2015-01-01

Previous studies implicate suprasegmental phonology in reading acquisition. However, little is known about how suprasegmental sensitivity develops or how it contributes to reading. Here, 130 Spanish primary-school children participated in this 2-year longitudinal study. Nonlinguistic rhythm, lexical-stress sensitivity and metrical-stress…

What is learned from longitudinal studies of advertising and youth drinking and smoking? A critical assessment.

PubMed

Nelson, Jon P

2010-03-01

This paper assesses the methodology employed in longitudinal studies of advertising and youth drinking and smoking behaviors. These studies often are given a causal interpretation in the psychology and public health literatures. Four issues are examined from the perspective of econometrics. First, specification and validation of empirical models. Second, empirical issues associated with measures of advertising receptivity and exposure. Third, potential endogeneity of receptivity and exposure variables. Fourth, sample selection bias in baseline and follow-up surveys. Longitudinal studies reviewed include 20 studies of youth drinking and 26 studies of youth smoking. Substantial shortcomings are found in the studies, which preclude a causal interpretation.

What is Learned from Longitudinal Studies of Advertising and Youth Drinking and Smoking? A Critical Assessment

PubMed Central

Nelson, Jon P

2010-01-01

This paper assesses the methodology employed in longitudinal studies of advertising and youth drinking and smoking behaviors. These studies often are given a causal interpretation in the psychology and public health literatures. Four issues are examined from the perspective of econometrics. First, specification and validation of empirical models. Second, empirical issues associated with measures of advertising receptivity and exposure. Third, potential endogeneity of receptivity and exposure variables. Fourth, sample selection bias in baseline and follow-up surveys. Longitudinal studies reviewed include 20 studies of youth drinking and 26 studies of youth smoking. Substantial shortcomings are found in the studies, which preclude a causal interpretation. PMID:20617009

Separation-Individuation of Late Adolescents : A Longitudinal Study

ERIC Educational Resources Information Center

Aslan, Sevda; Gelbal, Selahattin

2016-01-01

The aim of this study was to demonstrate the change in separation-individuation between late adolescents in the first, second, third and fourth year of higher education. The study sample used for this longitudinal study consisted of 148 students attending class studies, computer education and science education departments of Kirikkale University.…

Longitudinal Surveys of Australian Youth (LSAY) 1998 Cohort: Wave 12 (2009)--Questionnaire. Technical Report 58A

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2010

2010-01-01

The Longitudinal Surveys of Australian Youth (LSAY) program studies the progress of several groups of young Australians as they move from school into post-secondary education and work. This technical paper contains the questionnaire for the LSAY 1998 cohort Wave 12 (2009) data set. [For the accompanying frequency tables, "Longitudinal Surveys…

Examining the Longitudinal Biliterate Trajectory of Emerging Bilingual Learners in a Paired Literacy Instructional Model

ERIC Educational Resources Information Center

Sparrow, Wendy; Butvilofsky, Sandra; Escamilla, Kathy; Hopewell, Susan; Tolento, Teresa

2014-01-01

This longitudinal study examines the biliteracy results of Spanish-English emerging bilingual students who participated in a K-5 paired literacy model in a large school district in Oregon. Spanish and English reading and writing data show longitudinal gains in students' biliterate development, demonstrating the potential of the model in developing…

Academic Motivation, Self-Concept, Engagement, and Performance in High School: Key Processes from a Longitudinal Perspective

ERIC Educational Resources Information Center

Green, Jasmine; Liem, Gregory Arief D.; Martin, Andrew J.; Colmar, Susan; Marsh, Herbert W.; McInerney, Dennis

2012-01-01

The study tested three theoretically/conceptually hypothesized longitudinal models of academic processes leading to academic performance. Based on a longitudinal sample of 1866 high-school students across two consecutive years of high school (Time 1 and Time 2), the model with the most superior heuristic value demonstrated: (a) academic motivation…

Optimal Assignment Methods in Three-Form Planned Missing Data Designs for Longitudinal Panel Studies

ERIC Educational Resources Information Center

Jorgensen, Terrence D.; Rhemtulla, Mijke; Schoemann, Alexander; McPherson, Brent; Wu, Wei; Little, Todd D.

2014-01-01

Planned missing designs are becoming increasingly popular, but because there is no consensus on how to implement them in longitudinal research, we simulated longitudinal data to distinguish between strategies of assigning items to forms and of assigning forms to participants across measurement occasions. Using relative efficiency as the criterion,…

Exploring Structural Dynamics within and between Sensory and Intellectual Functioning in Old and Very Old Age: Longitudinal Evidence from the Berlin Aging Study

ERIC Educational Resources Information Center

Ghisletta, Paolo; Lindenberger, Ulman

2005-01-01

Cross-sectional and longitudinal analyses of age-heterogeneous samples have revealed correlational links between and within intellectual, sensory, and sensorimotor domains. Due to basic limitations of cross-sectional designs and a reluctance to disentangle antecedent-consequent relations in longitudinal designs, the functional significance and…

The natural course of anxiety disorders in the elderly: a systematic review of longitudinal trials.

PubMed

Sami, Musa Basseer; Nilforooshan, Ramin

2015-07-01

The anxiety disorders are a prevalent mental health problem in older age with a considerable impact on quality of life. Until recently there have been few longitudinal studies on anxiety in this age group, consequently most of the evidence to date has been cross-sectional in nature. We undertook a literature search of Medline, PsycINFO, the Cochrane trials database and the TRIP medical database to identify longitudinal studies which would help elucidate natural history and prognosis of anxiety disorders in the elderly. We identified 12 papers of 10 longitudinal studies in our Review. This represented 34,691 older age participants with 5,199 with anxiety disorders including anxious depression and 3,532 individuals with depression without anxiety. Relapse rates of anxiety disorders are high over 6 year follow-up with considerable migration to mixed anxiety-depression and pure depressive mood episodes. Mixed anxiety-depression appears to be a poorer prognostic state than pure anxiety or pure depression with higher relapse rates across studies. In community settings treatment rates are low with 7-44% of the anxious elderly treated on antidepressant medications. To our knowledge this is the first Systematic Review of longitudinal trials of anxiety disorders in older people. Major longitudinal studies of the anxious elderly are establishing the high risk of relapse and persistence alongside the progression to depression and anxiety depression states. There remains considerable under-treatment in community studies. Specialist assessment and treatment and major public health awareness of the challenges of anxiety disorders in the elderly are required.

Longitudinal muscle of the esophagus: its role in esophageal health and disease.

PubMed

Mittal, Ravinder K

2013-07-01

The muscularis propria of the esophagus is organized into circular and longitudinal muscle layers. The function of the longitudinal muscle and its role in bolus propulsion are not clear. The goal of this review is to summarize what is known of the role of the longitudinal muscle in health, as well as in sensory and motor disorders of the esophagus. Simultaneous manometry and ultrasound imaging reveal that, during peristalsis, the two muscle layers of the esophagus contract in perfect synchrony. On the contrary, during transient lower esophageal sphincter (LES) relaxation, longitudinal muscle contracts independent of the circular muscle. Recent studies have provided novel insights into the role of the longitudinal muscle in LES relaxation and descending relaxation of the esophagus. In certain diseases (e.g. some motility disorders of the esophagus), there is discoordination between the two muscle layers, which likely plays an important role in the genesis of dysphagia and delayed esophageal emptying. There is close temporal correlation between prolonged contractions of the longitudinal muscles of the esophagus and esophageal 'angina-like' pain. Novel techniques to record longitudinal muscle contraction are reviewed. Longitudinal muscles of the esophagus play a key role in the physiology and pathophysiology of esophageal sensory and motor function. Neuro-pharmacologic controls of circular and longitudinal muscle are different, which provides an opportunity for the development of novel pharmacological therapies in the treatment of esophageal sensory and motor disorders.

Early Childhood Longitudinal Study, Kindergarten Class of 2010-11 (ECLS-K:2011). User's Manual for the ECLS-K:2011 Kindergarten-First Grade Data File and Electronic Codebook, Public Version. NCES 2015-078

ERIC Educational Resources Information Center

Tourangeau, Karen; Nord, Christine; Lê, Thanh; Wallner-Allen, Kathleen; Hagedorn, Mary C.; Leggitt, John; Najarian, Michelle

2015-01-01

This manual provides guidance and documentation for users of the longitudinal kindergarten-first grade (K-1) data file of the Early Childhood Longitudinal Study, Kindergarten Class of 2010-11 (ECLS-K:2011). It mainly provides information specific to the first-grade rounds of data collection. Data for the ECLS-K:2011 are released in both a…

Longitudinal research and data collection in primary care.

PubMed

van Weel, Chris

2005-01-01

This article reviews examples of and experience with longitudinal research in family medicine. The objective is to use this empirical information to formulate recommendations for improving longitudinal research. The article discusses 3 longitudinal studies from the Nijmegen academic family practice research network: 1 on the prognosis of depression and 1 each on the prognosis of and outcomes of care for type 2 diabetes mellitus. The Nijmegen network has recorded all episodes of morbidity encountered in Dutch family medicine since 1971 in a stable practice population. This network's experience is evaluated to identify lessons that may help other practice-based research networks (PBRNs) in pursuing longitudinal research. In terms of external conditions (conditions related to the general setting), the stability of a population and a high level of continuity of care substantially enhance the ability to perform longitudinal research. In terms of internal conditions (conditions related to the PBRN), motivation of family physicians and their staff to conduct ongoing data collection, and their ownership of the data are key for success. Other critical internal conditions include standardization of data; collection of data by clinician-friendly means; training of family physicians and their staff in data collection, as well as meetings for discussion of this task; provision of feedback to practices on the research findings; use of standard procedures to promote adherence to data collection; availability of facilities for regular measurement of patients' health status or chart review; and use of mechanisms for tracking patients who leave the practice area. Insight from existing experience suggests that longitudinal research can be enhanced in PBRNs. The best way forward is to build longitudinal data collection by drawing on lessons from successful studies. Primary care research policy should advocate for a role of longitudinal research and stimulate its development in PBRNs under favorable population circumstances.

The ONS Longitudinal Study--a prestigious past and a bright future.

PubMed

Goldring, Shayla; Newman, Jim

2010-01-01

This issue of Population Trends includes a number of articles and reports resulting from research based on the ONS Longitudinal Study (ONS LS). They have been drawn together in one issue to highlight the value of this type of study for demographic research.2009 marked the 35th anniversary of the establishment of the ONS LS. The study now contains data from the last four censuses (1971 to 2001), linked to vital events data since 1971, for a sample of one per cent of the population of England and Wales.More recently, sister studies have been established in Scotland and Northern Ireland. The Scottish Longitudinal Study (SLS) started with 1991 Census data and the Northern Ireland Longitudinal Study (NILS)started with 2001 Census data.The lead article in this issue comes from an exemplar project that was established to explore how to utilise the three studies to carry out UK-wide longitudinal analysis. Two different methods were used to analyse socio-economic and country level differences in health and mortality across the studies. The article summarises the results of this analysis, reports on the relative strengths of the different methods used, and draws attention to a number of new resources that have been developed by the project researchers as aids to using all three studies.This is an excellent example of collaborative working across the UK, involving researchers from the Centre for Longitudinal Study Information and User Support (CeLSIUS) at the London School of Hygiene and Tropical Medicine, the Longitudinal Studies Centre - Scotland (LSCS) at the University of St.Andrews and the Northern Ireland Longitudinal Study - Research Support Unit (NILS-RSU) at Queen's University Belfast. The project also involved collaboration between ONS, the General Register Office for Scotland (GROS) and the Northern Ireland Statistics and Research Agency (NISRA) to ensure the secure transfer and handling of data from the three studies so that it could be brought together in one place for analysis.The other ONS LS-based articles and reports in this edition largely focus on research into issues related to families and households, as summarised below: A collaborative project involving Ben Wilson (ONS) and Rachel Stuchbury (CeLSIUS) comparing the stability of partnerships involving marriage and cohabitation.A project looking at transitions in children's experience of living in a workless household and how this varies by ethnic group, submitted by Lucinda Platt (Institute for Social & Economic Research, University of Essex).An article on the effect of a change in the census definition of a child between 1991 and 2001 submitted by Emily Grundy, Rachel Stuchbury and Harriet Young (CeLSIUS).The remainder of this introductory article will focus on the ONS LS, its history and some examples of its use, and gives a summary of planned developments over the coming years. Please refer to the contact details at the end of the article if you require further information on any of the three longitudinal studies.

A Semiparametric Approach to Simultaneous Covariance Estimation for Bivariate Sparse Longitudinal Data

PubMed Central

Das, Kiranmoy; Daniels, Michael J.

2014-01-01

Summary Estimation of the covariance structure for irregular sparse longitudinal data has been studied by many authors in recent years but typically using fully parametric specifications. In addition, when data are collected from several groups over time, it is known that assuming the same or completely different covariance matrices over groups can lead to loss of efficiency and/or bias. Nonparametric approaches have been proposed for estimating the covariance matrix for regular univariate longitudinal data by sharing information across the groups under study. For the irregular case, with longitudinal measurements that are bivariate or multivariate, modeling becomes more difficult. In this article, to model bivariate sparse longitudinal data from several groups, we propose a flexible covariance structure via a novel matrix stick-breaking process for the residual covariance structure and a Dirichlet process mixture of normals for the random effects. Simulation studies are performed to investigate the effectiveness of the proposed approach over more traditional approaches. We also analyze a subset of Framingham Heart Study data to examine how the blood pressure trajectories and covariance structures differ for the patients from different BMI groups (high, medium and low) at baseline. PMID:24400941

Learning-based subject-specific estimation of dynamic maps of cortical morphology at missing time points in longitudinal infant studies.

PubMed

Meng, Yu; Li, Gang; Gao, Yaozong; Lin, Weili; Shen, Dinggang

2016-11-01

Longitudinal neuroimaging analysis of the dynamic brain development in infants has received increasing attention recently. Many studies expect a complete longitudinal dataset in order to accurately chart the brain developmental trajectories. However, in practice, a large portion of subjects in longitudinal studies often have missing data at certain time points, due to various reasons such as the absence of scan or poor image quality. To make better use of these incomplete longitudinal data, in this paper, we propose a novel machine learning-based method to estimate the subject-specific, vertex-wise cortical morphological attributes at the missing time points in longitudinal infant studies. Specifically, we develop a customized regression forest, named dynamically assembled regression forest (DARF), as the core regression tool. DARF ensures the spatial smoothness of the estimated maps for vertex-wise cortical morphological attributes and also greatly reduces the computational cost. By employing a pairwise estimation followed by a joint refinement, our method is able to fully exploit the available information from both subjects with complete scans and subjects with missing scans for estimation of the missing cortical attribute maps. The proposed method has been applied to estimating the dynamic cortical thickness maps at missing time points in an incomplete longitudinal infant dataset, which includes 31 healthy infant subjects, each having up to five time points in the first postnatal year. The experimental results indicate that our proposed framework can accurately estimate the subject-specific vertex-wise cortical thickness maps at missing time points, with the average error less than 0.23 mm. Hum Brain Mapp 37:4129-4147, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Are Sibling Relationships Protective? A Longitudinal Study

ERIC Educational Resources Information Center

Gass, Krista; Jenkins, Jennifer; Dunn, Judy

2007-01-01

Background: Although the protective effects of familial and parental support have been studied extensively in the child psychopathology literature, few studies have explored the protective quality of positive sibling relationships. Methods: A two-wave longitudinal design was used to examine the protective effect of positive sibling relationships…

A longitudinal, collaborative, practice-based learning and improvement model to improve post-discharge heart failure outcomes.

PubMed

Anagnostou, Valsamo K; Bailey, Grant; Sze, Edward; Hay, Seonaid; Hyson, Anne; Federman, Daniel G

2014-01-01

Practice-based learning and improvement is one of the Accreditation Council of Graduate Medical Education's core competencies fortrainees. Residencyprograms have grappled with how to accomplish this goal. We describe our institution's unique, longitudinal post-graduate year process and project. West Haven, VA Medical Center. Yale University School of Medicine junior residents on ambulatory electives and faculty preceptor. Longitudinal program aimed to decrease re-admissions for hospitalized patients with congestive heart failure. We feel that our longitudinal project is a novel innovation worthy of further study.

First trimester maternal adiposity is associated with infant body fat at age 2 weeks: A longitudinal follow-up study

USDA-ARS?s Scientific Manuscript database

Maternal obesity has been shown to be associated with childhood obesity risk in both experimental and epidemiological studies. However, longitudinal studies carefully evaluating other contributors to fetal and infant body fat accretion are lacking. The objective of this study was to evaluate the eff...

Community College Students: Goals, Academic Preparation, and Outcomes. Postsecondary Education Descriptive Analysis Reports.

ERIC Educational Resources Information Center

Hoachlander, Gary; Sikora, Anna C.; Horn, Laura

This document profiles the goals, preparation, and outcomes of community college students using three data sources: the 1999-2000 National Postsecondary Student Aid Study, the 1996/01 Beginning Postsecondary Students Longitudinal Study, and the National Educational Longitudinal Study of 1988, Fourth Follow-up. This study addresses the following…

A comparison of response rates in the English Longitudinal Study of Ageing and the Health and Retirement Study

PubMed Central

Cheshire, Hayley; Ofstedal, Mary Beth; Scholes, Shaun; Schroeder, Mathis

2013-01-01

Survey response rates are an important measure of the quality of a survey; this is true for both longitudinal and cross-sectional surveys. However, the concept of a response rate in the context of a panel survey is more complex than is the case for a cross-sectional survey. There are typically many different response rates that can be calculated for a panel survey, each of which may be relevant for a specific purpose. The main objective of our paper is to document and compare response rates for two long-term panel studies of ageing, the English Longitudinal Study of Ageing (ELSA) and the Health and Retirement Study (HRS) in the United States. To guide our selection and calculation of response rates for the two studies, we use a framework that was developed by Peter Lynn (2005) and present several different types of longitudinal response rates for the two surveys. We discuss similarities and differences in the study designs and protocols and how some of the differences affect comparisons of response rates across the two studies. PMID:24432049

Calorimetria nucleare in collisioni tra ioni pesanti ad energie intermedie

NASA Astrophysics Data System (ADS)

Spezzi, L.

2002-07-01

Nel presente lavoro di tesi ci si e' occupati di uno studio sistematico di misure di temperatura ed energia di eccitazione in sistemi nucleari formati in reazioni tra ioni pesanti ad energie intermedie. La temperatura a stata misurata tramite due diversi metodi: rapporto tra le rese di isotopi che differiscono di uno stesso numero di nucleoni ( d/t-3He/4He , 3He/4He -6Li/7Li) - temperatura isotopica -, e rapporto tra le popolazioni degli stati eccitati in frammenti instabili (5Li e 6Li) che decadono in particelle leggere in coincidenza - temperatura di emissione. Le misure in esame sono state effettuate presso i Laboratori Nazionali del Sud per i sistemi 93Nb+93Nb, 93Nb+116,124Sn, 116,120Sn+116,124Sn e 116Sn+93Nb ad energie comprese tra 17 e 40 A MeV. L'apparato di rivelazione era costituito da un odoscopio ad alta granularite (96 telescopi Si (50micron)-Si(300micron)-CsI(Tl) ) e basse soglie di rivelazione, utilizzato sia per identificare risonanze in frammenti eccitati che per misure di rese di isotopi di frammenti con 2<=Z<=6, e dal multirivelatore FIASCO che, grazie alla misura contemporanea di posizione e tempo di volo dei frammenti provenienti dal proiettile (PLF - Projectile Like Fragments) e dal bersaglio (TLF - Target Like Fragment), e' stato utilizzato per misurare direttamente l'energia di eccitazione del sistema in studio. Analisi precedenti, condotte nell'ambito di varie collaborazioni, hanno messo in evidenza la possible esistenza di una transizione di fase liquido-gas del primo ordine nella materia nucleare. In tale contesto, ci siamo occupati di una verifica della curva calorica nucleare, ovvero della correlazione esistente fra temperatura ed energia di eccitazione del sistema, indagando, nel contempo, sulla sua dipendenza dalla massa del sistema che si frammenta. Si e' effettuato, inoltre, un confronto fra i due diversi metodi di misura della temperatura (temperatura isotopica e di emissione): l'andamento plateau-like della curva calorica e' stato confermato sia dalle temperature isotopiche che dalle temperature di emissione. Le "temperature limite", ovvero quelle relative all'andamento plateau-like della curva calorica, misurate per i vari sistemi studiati, sono state confrontate con quelle attualmente disponibili in letteratura, confermando la dipendenza dalla massa del sistema di tale grandezza.

A Longitudinal Study of Gender-Related Cognition and Behaviour

ERIC Educational Resources Information Center

Campbell, Anne; Shirley, Louisa; Candy, Julia

2004-01-01

Gender schema theory proposes that children's acquisition of gender labels and gender stereotypes informs gender-congruent behaviour. Most previous studies have been cross-sectional and do not address the temporal relationship between knowledge and behaviour. We report the results of a longitudinal study of gender knowledge and sex-typed behaviour…

Longitudinal Studies--Are They Worth It?

ERIC Educational Resources Information Center

Cowley, Judith

A longitudinal study of otitis media in young children, begun in 1981, aimed to provide information on the incidence and prevalence of otitis media in young children in the Newcastle (England) region and to follow their academic progress. Subjects selected for the study were kindergartners in five schools and represented an ethnically homogeneous…

The Stability of General Intelligence from Early Adulthood to Middle-Age

ERIC Educational Resources Information Center

Larsen, Lars; Hartmann, Peter; Nyborg, Helmuth

2008-01-01

Early cross-sectional studies suggested that cognitive functions begin to decline in young adulthood, whereas the first longitudinal studies suggested that they are mainly stable in adulthood. A number of more contemporary longitudinal studies support the stability hypothesis. However, drop out effects have the consequence that most longitudinal…

Giftedness, Trauma, and Development: A Qualitative, Longitudinal Case Study

ERIC Educational Resources Information Center

Peterson, Jean Sunde

2014-01-01

A qualitative, longitudinal, phenomenological case study explored how a gifted female experienced various life events and aspects of development during adolescence and young adulthood (ages 15-30 years), particularly as related to multiple traumatic experiences, which were revealed late in the first year of the study. Additional experiences, well…

A Longitudinal Study of the Determinants and Outcomes of Career Change

ERIC Educational Resources Information Center

Carless, Sally A.; Arnup, Jessica L.

2011-01-01

The present longitudinal field study investigated the antecedents and consequences of an actual career change. The framework for this study was Rhodes and Doering's (1983) model of career change. We examined the effect of individual and organisational characteristics on career change behaviour. The individual characteristics were: traits (Openness…

76 FR 78906 - Notice of Submission for OMB Review

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-20

... assessment in algebraic skills, reasoning, and problem solving and, like past studies, will survey students... Education Sciences Type of Review: Revision. Title of Collection: High School Longitudinal Study of 2009... Estimated Annual Burden Hours: 24,607. Abstract: The High School Longitudinal Study of 2009 (HSLS: 09) is a...

75 FR 62806 - Notice of Proposed Information Collection Requests

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-13

... math courses, majors, and careers. This study includes a new student assessment in algebraic skills... Review: Revision. Title of Collection: High School Longitudinal Study of 2009 (HSLS:09) First Follow-up.... Total Estimated Number of Annual Burden Hours: 615. Abstract: The High School Longitudinal Study of 2009...

Muscle Fiber Size and Function in Elderly Humans: A Longitudinal Study

USDA-ARS?s Scientific Manuscript database

Cross-sectional studies are likely to underestimate age-related changes in skeletal muscle strength and mass. The purpose of this longitudinal study was to assess whole muscle and single muscle fiber alterations in the same cohort of 12 older (mean age: start of study=71.1+/-5.4 yrs and end of study...

Longitudinal Surveys of Australian Youth (LSAY) 1998 Cohort: Wave 12 (2009)--Frequency Tables. Technical Report 58B

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2010

2010-01-01

The Longitudinal Surveys of Australian Youth (LSAY) program studies the progress of several groups of young Australians as they move from school into post-secondary education and work. This technical paper contains the frequency tables for the LSAY 1998 cohort Wave 12 (2009) data set. [For the accompanying questionnaire, "Longitudinal Surveys…

Longitudinal Surveys of Australian Youth (LSAY): 2006 Cohort Wave 4 (2009)--Frequency Tables. Technical Report 56B

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2010

2010-01-01

The Longitudinal Surveys of Australian Youth (LSAY) program studies the progress of several groups of young Australians as they move from school into post-secondary education and work. This technical paper contains the frequency tables for the LSAY 2006 cohort Wave 4 (2009) data set. [For the "Longitudinal Surveys of Australian Youth (LSAY):…

Longitudinal Surveys of Australian Youth (LSAY): 2006 Cohort Wave 4 (2009)--Questionnaire. Technical Report 56A

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2010

2010-01-01

The Longitudinal Surveys of Australian Youth (LSAY) program studies the progress of several groups of young Australians as they move from school into post-secondary education and work. This technical paper contains the questionnaire for the LSAY 2006 cohort Wave 4 (2009) data set. [For the "Longitudinal Surveys of Australian Youth (LSAY):…

Testing a Longitudinal Model of the Relationships among High Risk Youths' Drug Sales, Drug Use and Participation in Index Crimes.

ERIC Educational Resources Information Center

Dembo, Richard; Wothke, Werner; Seeberger, William; Shemwell, Marina; Pacheco, Kimberly; Rollie, Matthew; Schmeidler, James; Livingston, Stephen; Hartsfield, Amy

2002-01-01

Baseline, one-year and two-year follow-up interviews were obtained from 164 arrested youths processed at a juvenile assessment center in a prospective longitudinal study. A structural equation model that included cross-sectional and longitudinal associations among drug (alcohol and marijuana), drug sales and index offenses was supported by the…

Motor and sensory function of the esophagus: revelations through ultrasound imaging.

PubMed

Mittal, Ravinder K

2005-04-01

Catheter based high frequency intraluminal ultrasound (HFIUS) imaging is a powerful tool to study esophageal sensory and motor function and dysfunction in vivo in humans. It has provided a number of important insights into the longitudinal muscle function of the esophagus. Based on the ultrasound images and intraluminal pressure recordings, it is clear that there is synchrony in the timing as well as the amplitude of contraction between the circular and the longitudinal muscle layers of the esophagus in normal subjects. On the other hand, in patients with spastic disorders of the esophagus, there is an asynchrony of contraction related to the timing and amplitude of contraction of the two muscle layers during peristalsis. Achalasia, diffuse esophageal spasm, and nutcracker esophagus (spastic motor disorders of the esophagus) are associated with hypertrophy of the circular as well as longitudinal muscle layers. A sustained contraction of the longitudinal muscle of the esophagus is temporally related to chest pain and heartburn and may very well be the cause of symptoms. Longitudinal muscle function of the esophagus can be studied in vivo in humans using dynamic ultrasound imaging. Longitudinal muscle dysfunction appears to be important in the motor and sensory disorders of the esophagus.

The Effects of Magnetic-Field Geometry on Longitudinal Oscillations of Solar Prominences: Cross-Sectional Area Variation for Thin Tubes

NASA Technical Reports Server (NTRS)

Luna, M.; Diaz, A. J.; Oliver, R.; Terradas, J.; Karpen, J.

2016-01-01

Solar prominences are subject to both field-aligned (longitudinal) and transverse oscillatory motions, as evidenced by an increasing number of observations. Large-amplitude longitudinal motions provide valuable information on the geometry of the filament channel magnetic structure that supports the cool prominence plasma against gravity. Our pendulum model, in which the restoring force is the gravity projected along the dipped field lines of the magnetic structure, best explains these oscillations. However, several factors can influence the longitudinal oscillations, potentially invalidating the pendulum model. Aims. The aim of this work is to study the influence of large-scale variations in the magnetic field strength along the field lines, i.e., variations of the cross-sectional area along the flux tubes supporting prominence threads. Methods. We studied the normal modes of several flux tube configurations, using linear perturbation analysis, to assess the influence of different geometrical parameters on the oscillation properties. Results. We found that the influence of the symmetric and asymmetric expansion factors on longitudinal oscillations is small.Conclusions. We conclude that the longitudinal oscillations are not significantly influenced by variations of the cross-section of the flux tubes, validating the pendulum model in this context.

Victimization Mediates the Longitudinal Association Between Depressive Symptoms and Violent Behaviors in Adolescence.

PubMed

Yu, Rongqin; Branje, Susan; Meeus, Wim; Koot, Hans M; van Lier, Pol; Fazel, Seena

2018-05-01

Despite evidence of a positive link between depressive symptoms and violent behaviors, the pathways underlying this longitudinal association remain unknown. Depressive symptoms might drive and reinforce victimization which in turn could increase risk of individuals becoming violent towards others. Thus, we tested whether victimization mediated the link between depressive symptoms and violent behaviors using a 6-year longitudinal study of a community sample of adolescents. The sample included 682 Dutch adolescents (54% boys) from an ongoing longitudinal study RADAR (Research on Adolescent Development and Relationships). From ages 13 to 18 years, depressive symptoms, victimization experiences, and violent behaviors were annually assessed. We conducted longitudinal mediation analyses to test pathways to violence in adolescents with depressive symptoms. Longitudinal analyses revealed that victimization mediated the association between depressive symptoms and violent behaviors from early to late adolescence. As part of this, we found that adolescents' depressive symptoms predicted victimization, and this victimization increased risk of subsequent violent behaviors. In conclusion, links between depressive symptoms and violent behaviors are potentially important to understand adolescent development. Decreasing the occurence of victimization is likely to be an important target for the prevention of violent behaviors in adolescents with depressive symptoms.

Composite marginal quantile regression analysis for longitudinal adolescent body mass index data.

PubMed

Yang, Chi-Chuan; Chen, Yi-Hau; Chang, Hsing-Yi

2017-09-20

Childhood and adolescenthood overweight or obesity, which may be quantified through the body mass index (BMI), is strongly associated with adult obesity and other health problems. Motivated by the child and adolescent behaviors in long-term evolution (CABLE) study, we are interested in individual, family, and school factors associated with marginal quantiles of longitudinal adolescent BMI values. We propose a new method for composite marginal quantile regression analysis for longitudinal outcome data, which performs marginal quantile regressions at multiple quantile levels simultaneously. The proposed method extends the quantile regression coefficient modeling method introduced by Frumento and Bottai (Biometrics 2016; 72:74-84) to longitudinal data accounting suitably for the correlation structure in longitudinal observations. A goodness-of-fit test for the proposed modeling is also developed. Simulation results show that the proposed method can be much more efficient than the analysis without taking correlation into account and the analysis performing separate quantile regressions at different quantile levels. The application to the longitudinal adolescent BMI data from the CABLE study demonstrates the practical utility of our proposal. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

Racial and Ethnic Differences in Longitudinal Patterns of Family Mealtimes: Link to Adolescent Fruit and Vegetable Consumption.

PubMed

Surjadi, Florensia F; Takeuchi, David T; Umoren, Josephine

2017-03-01

To examine the longitudinal patterns of family mealtimes across racial/ethnic groups and to investigate whether the associations between longitudinal patterns of family mealtimes, baseline family and demographic characteristics, and healthy food consumption in adolescence differ by race/ethnicity. Data from the Early Childhood Longitudinal Study spanning from kindergarten to eighth grade were used for this study. Longitudinal patterns of family mealtimes and their link to baseline characteristics and healthy food consumption in adolescence, as defined by fruit and vegetable intakes, were determined using latent growth curves. From childhood to adolescence, family mealtimes were stable among Asian families. Although Hispanic families displayed a downward pattern, mealtimes declined more steeply in non-Hispanic white and black families. The links among family mealtimes, baseline characteristics, and healthy food consumption were not observed equally across racial/ethnic groups. Differences in longitudinal patterns of family mealtimes and in the association between family mealtimes and adolescent healthy food consumption across racial/ethnic groups call for targeted intervention in this nutritionally vulnerable period. Copyright © 2016 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

The Daskop Granophyre Dyke: Inhomogeneous clast distribution and chemistry

NASA Astrophysics Data System (ADS)

Kovaleva, Elizaveta; Huber, Matthew S.; Somers, Andrew; Bateman, Stuart

2017-04-01

The Vredefort Granophyre is present in the central basement of the Vredefort impact structure as a set of dykes up to 9 km long and up to 65 m wide and is considered to be the remnant of the impact melt sheet (e.g. French et al. 1989; French and Nielsen 1990). The dykes intruded into the floor of the structure's core during the crater modification and settling stages (e.g. Therriault et al. 1996). Granophyre is typically considered a well-homogenized and uniform melt (e.g., Nel 1927; Gibson and Reimold 2008). This study presents new insights into the chemical variety and inhomogeneous clast distribution of the Vredefort granophyre. The Granophyre dyke on the farm Daskop is located in the core of the impact structure and hosted by granitic gneiss of the Archean basement. The clast distribution was mapped in the eastern half of the dyke. Additionally, non-destructive geochemical methods (handheld µXRF and LIBS systems) were used to obtain chemical analysis of the dyke along strike. The map of clast distribution in the granophyre dyke reveals an inhomogeneous content of clasts, with a consistently higher concentration of clasts along the southern contact. This distribution suggests that either 1) the dyke orientation is non-vertical, allowing gravitational settling to affect the distribution of the clasts after the dyke intruded; or 2) that clasts were preferentially entrained along the southern margin of the dyke. Clast frequency also differs along strike. Many elongated clasts are oriented parallel to the dyke walls, indicating flow. We have also documented linear structures resembling flow channels. These structures are strictly parallel to the dyke walls and have a finer texture than the host granophyre. These may represent differentiation of the melt during crystallization. Chemical inhomogeneity of granophyre dyke has also been documented along strike. Such chemical variation may reflect local differences in the relative amounts of target rocks incorporated into the melt (e.g. French and Nielsen 1990). References French B.M., Nielsen R.L. (1990) Vredefort bronzite granophyre: chemical evidence for origin as a meteorite impact melt. Tectonophysics 171:119-138. French B.M., Orth C.J., Quintana L.R. (1989) Iridium in the Vredefort Bronzite Granophyre - Impact melting and limits on a possible extraterrestrial component. Proceedings, 19th Lunar and Planetary Science Conference. pp.733-744. Gibson R.L., Reimold W.U. (2008) Geology of the Vredefort impact structure, a guide to sites of interest. Pretoria: Council for Geoscience. 181 p. Nel L.T. (1927) The geology of the country around Vredefort - An explanation of the geological map. Pretoria: South Africa Geological Survey. 134 p. Therriault A.M., Reimold W.U., Reid A.M. (1996) Field relations and petrography of the Vredefort Granophyre. South African Journal of Geology 99:1-21.

Adventive hydrothermal circulation on Stromboli volcano (Aeolian Islands, Italy) revealed by geophysical and geochemical approaches: Implications for general fluid flow models on volcanoes

NASA Astrophysics Data System (ADS)

Finizola, A.; Ricci, T.; Deiana, R.; Cabusson, S. Barde; Rossi, M.; Praticelli, N.; Giocoli, A.; Romano, G.; Delcher, E.; Suski, B.; Revil, A.; Menny, P.; Di Gangi, F.; Letort, J.; Peltier, A.; Villasante-Marcos, V.; Douillet, G.; Avard, G.; Lelli, M.

2010-09-01

On March 15th 2007 a paroxysmal explosion occurred at the Stromboli volcano. This event generated a large amount of products, mostly lithic blocks, some of which impacted the ground as far as down to 200 m a.s.l., about 1.5 km far away from the active vents. Two days after the explosion, a new vapour emission was discovered on the north-eastern flank of the volcanic edifice, at 560 m a.s.l., just above the area called "Nel Cannestrà". This new vapour emission was due to a block impact. In order to investigate the block impact area to understand the appearance of the vapour emission, we conducted on May 2008 a multidisciplinary study involving Electrical Resistivity Tomography (ERT), Ground Penetrating Radar (GPR), Self-Potential (SP), CO 2 soil diffuse degassing and soil temperature surveys. This complementary data set revealed the presence of an anomalous conductive body, probably related to a shallow hydrothermal level, at about 10-15 m depth, more or less parallel to the topography. It is the first time that such a hydrothermal fluid flow, with a temperature close to the water boiling point (76 °C) has been evidenced at Stromboli at this low elevation on the flank of the edifice. The ERT results suggest a possible link between (1) the main central hydrothermal system of Stromboli, located just above the plumbing system feeding the active vents, with a maximum of subsurface soil temperature close to 90 °C and limited by the NeoStromboli summit crater boundary and (2) the investigated area of Nel Cannestrà, at ~ 500 m a.s.l., a buried eruptive fissure active 9 ka ago. In parallel, SP and CO 2 soil diffuse degassing measurements suggest in this sector at slightly lower elevation from the block impact crater a magmatic and hydrothermal fluid rising system along the N41° regional fault. A complementary ERT profile, on May 2009, carried out from the NeoStromboli crater boundary down to the block impact crater displayed a flank fluid flow apparently connected to a deeper system. The concept of shallow hydrothermal level have been compared to similar ERT results recently obtained on Mount Etna and La Fossa cone of Vulcano. This information needs to be taken into account in general fluid flow models on volcanoes. In particular, peripheral thermal waters (as those bordering the north-eastern coast of Stromboli) could be contaminated by hydrothermal and magmatic fluids coming from regional faults but also from the summit.

Cross-Sectional Analysis of Longitudinal Mediation Processes.

PubMed

O'Laughlin, Kristine D; Martin, Monica J; Ferrer, Emilio

2018-01-01

Statistical mediation analysis can help to identify and explain the mechanisms behind psychological processes. Examining a set of variables for mediation effects is a ubiquitous process in the social sciences literature; however, despite evidence suggesting that cross-sectional data can misrepresent the mediation of longitudinal processes, cross-sectional analyses continue to be used in this manner. Alternative longitudinal mediation models, including those rooted in a structural equation modeling framework (cross-lagged panel, latent growth curve, and latent difference score models) are currently available and may provide a better representation of mediation processes for longitudinal data. The purpose of this paper is twofold: first, we provide a comparison of cross-sectional and longitudinal mediation models; second, we advocate using models to evaluate mediation effects that capture the temporal sequence of the process under study. Two separate empirical examples are presented to illustrate differences in the conclusions drawn from cross-sectional and longitudinal mediation analyses. Findings from these examples yielded substantial differences in interpretations between the cross-sectional and longitudinal mediation models considered here. Based on these observations, researchers should use caution when attempting to use cross-sectional data in place of longitudinal data for mediation analyses.

Sleep-wake profiles predict longitudinal changes in manic symptoms and memory in young people with mood disorders.

PubMed

Robillard, Rébecca; Hermens, Daniel F; Lee, Rico S C; Jones, Andrew; Carpenter, Joanne S; White, Django; Naismith, Sharon L; Southan, James; Whitwell, Bradley; Scott, Elizabeth M; Hickie, Ian B

2016-10-01

Mood disorders are characterized by disabling symptoms and cognitive difficulties which may vary in intensity throughout the course of the illness. Sleep-wake cycles and circadian rhythms influence emotional regulation and cognitive functions. However, the relationships between the sleep-wake disturbances experienced commonly by people with mood disorders and the longitudinal changes in their clinical and cognitive profile are not well characterized. This study investigated associations between initial sleep-wake patterns and longitudinal changes in mood symptoms and cognitive functions in 50 young people (aged 13-33 years) with depression or bipolar disorder. Data were based on actigraphy monitoring conducted over approximately 2 weeks and clinical and neuropsychological assessment. As part of a longitudinal cohort study, these assessments were repeated after a mean follow-up interval of 18.9 months. No significant differences in longitudinal clinical changes were found between the participants with depression and those with bipolar disorder. Lower sleep efficiency was predictive of longitudinal worsening in manic symptoms (P = 0.007). Shorter total sleep time (P = 0.043) and poorer circadian rhythmicity (P = 0.045) were predictive of worsening in verbal memory. These findings suggest that some sleep-wake and circadian disturbances in young people with mood disorders may be associated with less favourable longitudinal outcomes, notably for subsequent manic symptoms and memory difficulties. © 2016 European Sleep Research Society.

Accelerated longitudinal designs: An overview of modelling, power, costs and handling missing data.

PubMed

Galbraith, Sally; Bowden, Jack; Mander, Adrian

2017-02-01

Longitudinal studies are often used to investigate age-related developmental change. Whereas a single cohort design takes a group of individuals at the same initial age and follows them over time, an accelerated longitudinal design takes multiple single cohorts, each one starting at a different age. The main advantage of an accelerated longitudinal design is its ability to span the age range of interest in a shorter period of time than would be possible with a single cohort longitudinal design. This paper considers design issues for accelerated longitudinal studies. A linear mixed effect model is considered to describe the responses over age with random effects for intercept and slope parameters. Random and fixed cohort effects are used to cope with the potential bias accelerated longitudinal designs have due to multiple cohorts. The impact of other factors such as costs and the impact of dropouts on the power of testing or the precision of estimating parameters are examined. As duration-related costs increase relative to recruitment costs the best designs shift towards shorter duration and eventually cross-sectional design being best. For designs with the same duration but differing interval between measurements, we found there was a cutoff point for measurement costs relative to recruitment costs relating to frequency of measurements. Under our model of 30% dropout there was a maximum power loss of 7%.

A novel pattern of longitudinal muscle contraction with subthreshold pharyngeal stimulus: a possible mechanism of lower esophageal sphincter relaxation.

PubMed

Leslie, Eric; Bhargava, Valmik; Mittal, Ravinder K

2012-03-01

A subthreshold pharyngeal stimulus induces lower esophageal sphincter (LES) relaxation and inhibits progression of ongoing peristaltic contraction in the esophagus. Recent studies show that longitudinal muscle contraction of the esophagus may play a role in LES relaxation. Our goal was to determine whether a subthreshold pharyngeal stimulus induces contraction of the longitudinal muscle of the esophagus and to determine the nature of this contraction. Studies were conducted in 16 healthy subjects. High resolution manometry (HRM) recorded pressures, and high frequency intraluminal ultrasound (HFIUS) images recorded longitudinal muscle contraction at various locations in the esophagus. Subthreshold pharyngeal stimulation was induced by injection of minute amounts of water in the pharynx. A subthreshold pharyngeal stimulus induced strong contraction and caudal descent of the upper esophageal sphincter (UES) along with relaxation of the LES. HFIUS identified longitudinal muscle contraction of the proximal (3-5 cm below the UES) but not the distal esophagus. Pharyngeal stimulus, following a dry swallow, blocked the progression of dry swallow-induced peristalsis; this was also associated with UES contraction and descent along with the contraction of longitudinal muscle of the proximal esophagus. We identify a unique pattern of longitudinal muscle contraction of the proximal esophagus in response to subthreshold pharyngeal stimulus, which we propose may be responsible for relaxation of the distal esophagus and LES through the stretch sensitive activation of myenteric inhibitory motor neurons.

Generation of double giant pulses in actively Q-switched lasers

NASA Astrophysics Data System (ADS)

Korobeynikova, A. P.; Shaikin, I. A.; Shaykin, A. A.; Koryukin, I. V.; Khazanov, E. A.

2018-04-01

Generation of a second giant pulse in a longitudinal mode neighbouring to the longitudinal mode possessing minimal losses is theoretically and experimentally studied in actively Q-switched lasers. A mathematical model is suggested for explaining the giant pulse generation in a laser with multiple longitudinal modes. The model makes allowance for not only a standing, but also a running wave for each cavity mode. Results of numerical simulation and data of experiments with a Nd : YLF laser explain the effect of second giant pulse generation in a neighbouring longitudinal mode. After a giant pulse in the mode with minimal losses is generated, the threshold for the neighbouring longitudinal mode is still exceeded due to the effect of burning holes in the population inversion spatial distribution.

Continuity of Genetic and Environmental Influences on Cognition across the Life Span: A Meta-Analysis of Longitudinal Twin and Adoption Studies

PubMed Central

Tucker-Drob, Elliot M.; Briley, Daniel A.

2014-01-01

The longitudinal rank-order stability of cognitive ability increases dramatically over the lifespan. Multiple theoretical perspectives have proposed that genetic and/or environmental mechanisms underlie the longitudinal stability of cognition, and developmental trends therein. However, the patterns of stability of genetic and environmental influences on cognition over the lifespan largely remain poorly understood. We searched for longitudinal studies of cognition that reported raw genetically-informative longitudinal correlations or parameter estimates from longitudinal behavior genetic models. We identified 150 combinations of time points and measures from 15 independent longitudinal samples. In total, longitudinal data came from 4,538 monozygotic twin pairs raised together, 7,777 dizygotic twin pairs raised together, 34 monozygotic twin pairs raised apart, 78 dizygotic twin pairs raised apart, 141 adoptive sibling pairs, and 143 non-adoptive sibling pairs, ranging in age from infancy through late adulthood. At all ages, cross-time genetic correlations and shared environmental correlations were substantially larger than cross-time nonshared environmental correlations. Cross-time correlations for genetic and shared environmental components were low during early childhood, increased sharply over child development, and remained relatively high from adolescence through late adulthood. Cross-time correlations for nonshared environmental components were low across childhood and increased gradually to moderate magnitudes in adulthood. Increasing phenotypic stability over child development was almost entirely mediated by genetic factors. Time-based decay of genetic and shared environmental stability was more pronounced earlier in child development. Results are interpreted in reference to theories of gene-environment interaction and correlation. PMID:24611582

Longitudinal and transverse right ventricular function in pulmonary hypertension: cardiovascular magnetic resonance imaging study from the ASPIRE registry

PubMed Central

Rajaram, Smitha; Capener, Dave; Elliot, Charlie; Condliffe, Robin; Wild, Jim M.; Kiely, David G.

2015-01-01

Abstract Right ventricular (RV) function is a strong predictor of outcome in cardiovascular diseases. Two components of RV function, longitudinal and transverse motion, have been investigated in pulmonary hypertension (PH). However, their individual clinical significance remains uncertain. The aim of this study was to determine the factors associated with transverse and longitudinal RV motion in patients with PH. In 149 treatment-naive patients with PH and 16 patients with suspected PH found to have mean pulmonary arterial pressure of <20 mmHg, cardiovascular magnetic resonance imaging was performed within 24 hours of right heart catheterization. In patients with PH, fractional longitudinal motion (fractional tricuspid annulus to apex distance [f-TAAD]) was significantly greater than fractional transverse motion (fractional septum to free wall distance [f-SFD]; P = 0.002). In patients without PH, no significant difference between f-SFD and f-TAAD was identified (P = 0.442). Longitudinal RV motion was singularly associated with RV ejection fraction independent of age, invasive hemodynamics, and cardiac magnetic resonance measurements (P = 0.024). In contrast, transverse RV motion was independently associated with left ventricular eccentricity (P = 0.036) in addition to RV ejection fraction (P = 0.014). In conclusion, RV motion is significantly greater in the longitudinal direction in patients with PH, whereas patients without PH have equal contributions of transverse and longitudinal motion. Longitudinal RV motion is primarily associated with global RV pump function in PH. Transverse RV motion not only reflects global pump function but is independently influenced by ventricular interaction in patients with PH. PMID:26401257

Longitudinal and transverse right ventricular function in pulmonary hypertension: cardiovascular magnetic resonance imaging study from the ASPIRE registry.

PubMed

Swift, Andrew J; Rajaram, Smitha; Capener, Dave; Elliot, Charlie; Condliffe, Robin; Wild, Jim M; Kiely, David G

2015-09-01

Right ventricular (RV) function is a strong predictor of outcome in cardiovascular diseases. Two components of RV function, longitudinal and transverse motion, have been investigated in pulmonary hypertension (PH). However, their individual clinical significance remains uncertain. The aim of this study was to determine the factors associated with transverse and longitudinal RV motion in patients with PH. In 149 treatment-naive patients with PH and 16 patients with suspected PH found to have mean pulmonary arterial pressure of <20 mmHg, cardiovascular magnetic resonance imaging was performed within 24 hours of right heart catheterization. In patients with PH, fractional longitudinal motion (fractional tricuspid annulus to apex distance [f-TAAD]) was significantly greater than fractional transverse motion (fractional septum to free wall distance [f-SFD]; P = 0.002). In patients without PH, no significant difference between f-SFD and f-TAAD was identified (P = 0.442). Longitudinal RV motion was singularly associated with RV ejection fraction independent of age, invasive hemodynamics, and cardiac magnetic resonance measurements (P = 0.024). In contrast, transverse RV motion was independently associated with left ventricular eccentricity (P = 0.036) in addition to RV ejection fraction (P = 0.014). In conclusion, RV motion is significantly greater in the longitudinal direction in patients with PH, whereas patients without PH have equal contributions of transverse and longitudinal motion. Longitudinal RV motion is primarily associated with global RV pump function in PH. Transverse RV motion not only reflects global pump function but is independently influenced by ventricular interaction in patients with PH.

Inspiring our future citizens and scientists: follow the Blue Paths (Percorsi nel Blu)!

NASA Astrophysics Data System (ADS)

Mioni, Erika; Stroobant, Mascha; Merlino, Silvia; Traverso, Roberto

2016-04-01

Very often we hear about scientific communication and education as separate and disconnected domains: in fact while the first one is seen more as a moment of disclosure for disseminating results and latest achievements and consequences (a look to our direct future), the second is, instead, identified as a formative moment in the long term, that often is based on obsolete and dated programs that refer to the past. What would happen if these two domains were, instead, considered as inseparable? As stated by Andrea Schleicher (OECD): "Schools have to prepare students for jobs that have not yet been created, technologies that have not yet been invented and problems that we don't know will arise." How to manage this challenge? The European Commission has proposed seven recommendations to follow for improving Science education and to bring more and more young people closer to STEM (Science, Technology, Engineering and Mathematics) disciplines. Especially three of them (Reccomendation n. 1, 4 and 7) pin out the to-do list for improving communication an education in Science, indicating that "a primary goal of science education across the EU should be to educate students both about the major explanations of the material world that science offers and about the way science works. Moreover teachers of science of the highest quality should be provided for students in primary and lower secondary school; moreover the emphasis in science education before 14 should be on engaging students with science and scientific phenomena (extended investigative work and 'hands-on' experimentation and not through a stress on the acquisition of canonical concepts). Last but not least: good quality teachers, with up to date knowledge and skills, are the foundation of any system of formal science education. Systems to ensure the recruitment, retention and continuous professional training of such individuals must be a policy priority in Europe". Blue Paths (Percorsi nel Blu) is a transversal project of Biological Sciences, carried out in a pilot school of La Spezia (ISA 2 "2 Giugno"), and that since several years involves students aged 4 to 18 years (and their families) in a long-term training program for environmental awareness and marine scientific research. The project is aimed at monitoring marine biocenosis (flora and fauna) from the upper and middle shore, using and integrating the Reef-Check Protocol (C.E.M. Coastal Environment Monitoring Protocol) with a new approach that motivates students to science, continuously over the years and bringing them closer to the work of Marine Scientists, raising awareness on biodiversity loss and the pollution within a specific area such as that of the Pelagos Sanctuary in the North Tyrrhenian and Ligurian Seas. Blue Paths (Percorsi nel Blu) is, hence, an example of education with a wider communication spectrum (not focused only to form a single class of students, but a whole community) and made possible thanks to a network of partners (including technology clusters, Institutions, Museums, Research Centers, Marine Protected Areas etc.). The presence of the network has allowed the enhancement of the Project under different points of view, including: - transformation in a participatory research project (the scientific results obtained by students are real products of research) of citizen science; - increase of educational opportunities (peer education, intergenerational education, tutoring); - increased visibility thanks to the participation in European projects for the Science Communication (European Researchers' Night project funded by the European Commission under the Marie Sklodowska-Curie actions); - enrichment of students' curriculum thanks to an adequate and real acquisition of key skills for future careers that can also inspire their actions as future citizens.

A long term study of pulmonary function among US refractory ceramic fibre workers

PubMed Central

LeMasters, Grace K; Hilbert, Timothy J; Levin, Linda S; Rice, Carol H; Borton, Eric K; Lockey, James E

2010-01-01

Background Cross-sectional studies have shown declines in lung function among refractory ceramic fibre (RCF) workers with increasing fibre exposure. This study followed current and former workers (n=1396) for up to 17 years and collected 5243 pulmonary function tests. Methods Cumulative fibre exposure and production years were categorised into exposure levels at five manufacturing locations. Conventional longitudinal models did not adequately partition age-related changes from other time-dependent variables. Therefore, a restricted cubic spline model was developed to account for the non-linear decline with age. Results Cumulative fibre >60 fibre-months/cc showed a significant loss in lung function at the first test. When results were examined longitudinally, cumulative exposure was confounded with age as workers with the highest cumulative exposure were generally older. A longitudinal model adjusted by age groups was implemented to control for this confounding. No consistent longitudinal loss in lung function was observed with RCF exposure. Smoking, initial weight and weight increase were significant factors. Conclusion No consistent decline was observed longitudinally with exposure to RCF, although cross-sectional and longitudinal findings were discordant. Confounding and accelerated lung function declines with ageing and the correlation of multiple time-dependent variables should be considered in order to minimise error and maximise precision. An innovative statistical methodology for these types of data is described. PMID:20798015

Longitudinal Relationships Between Productive Activities and Functional Health in Later Years: A Multivariate Latent Growth Curve Modeling Approach.

PubMed

Choi, Eunhee; Tang, Fengyan; Kim, Sung-Geun; Turk, Phillip

2016-10-01

This study examined the longitudinal relationships between functional health in later years and three types of productive activities: volunteering, full-time, and part-time work. Using the data from five waves (2000-2008) of the Health and Retirement Study, we applied multivariate latent growth curve modeling to examine the longitudinal relationships among individuals 50 or over. Functional health was measured by limitations in activities of daily living. Individuals who volunteered, worked either full time or part time exhibited a slower decline in functional health than nonparticipants. Significant associations were also found between initial functional health and longitudinal changes in productive activity participation. This study provides additional support for the benefits of productive activities later in life; engagement in volunteering and employment are indeed associated with better functional health in middle and old age. © The Author(s) 2016.

Dynamic Bayesian network modeling for longitudinal brain morphometry

PubMed Central

Chen, Rong; Resnick, Susan M; Davatzikos, Christos; Herskovits, Edward H

2011-01-01

Identifying interactions among brain regions from structural magnetic-resonance images presents one of the major challenges in computational neuroanatomy. We propose a Bayesian data-mining approach to the detection of longitudinal morphological changes in the human brain. Our method uses a dynamic Bayesian network to represent evolving inter-regional dependencies. The major advantage of dynamic Bayesian network modeling is that it can represent complicated interactions among temporal processes. We validated our approach by analyzing a simulated atrophy study, and found that this approach requires only a small number of samples to detect the ground-truth temporal model. We further applied dynamic Bayesian network modeling to a longitudinal study of normal aging and mild cognitive impairment — the Baltimore Longitudinal Study of Aging. We found that interactions among regional volume-change rates for the mild cognitive impairment group are different from those for the normal-aging group. PMID:21963916

Mixed-effects location and scale Tobit joint models for heterogeneous longitudinal data with skewness, detection limits, and measurement errors.

PubMed

Lu, Tao

2017-01-01

The joint modeling of mean and variance for longitudinal data is an active research area. This type of model has the advantage of accounting for heteroscedasticity commonly observed in between and within subject variations. Most of researches focus on improving the estimating efficiency but ignore many data features frequently encountered in practice. In this article, we develop a mixed-effects location scale joint model that concurrently accounts for longitudinal data with multiple features. Specifically, our joint model handles heterogeneity, skewness, limit of detection, measurement errors in covariates which are typically observed in the collection of longitudinal data from many studies. We employ a Bayesian approach for making inference on the joint model. The proposed model and method are applied to an AIDS study. Simulation studies are performed to assess the performance of the proposed method. Alternative models under different conditions are compared.

Cohort profile: the Motorik-Modul Longitudinal Study: physical fitness and physical activity as determinants of health development in German children and adolescents.

PubMed

Wagner, Matthias O; Bös, Klaus; Jekauc, Darko; Karger, Claudia; Mewes, Nadine; Oberger, Jennifer; Reimers, Anne K; Schlenker, Lars; Worth, Annette; Woll, Alexander

2014-10-01

The Motorik-Modul (MoMo) Longitudinal Study aims to contribute to long-term improvement in the health of German children and adolescents by focusing on: (i) the development of physical fitness and physical activity (including period effects); (ii) the individual and physical/social environmental determinants of the development of physical fitness and physical activity; and (iii) the impact of physical fitness and physical activity on the development of physical and mental health. The MoMo Longitudinal Study began with a nationwide representative sample of 4529 children and adolescents who ranged in age from 4-17 years at the study baseline (2003-2006). The first survey wave of the MoMo Longitudinal Study was conducted between 2009 and 2012, with two subsequent survey waves to be conducted between 2014 and 2016 and 2018 and 2020, respectively. The MoMo Longitudinal Study includes a physical fitness test profile, a physical activity questionnaire, and subjective and objective measures of health from the German Health Interview and Examination Survey (KiGGS). Data access is provided on request (alexander.woll@kit.edu). For further information, including a complete list of publications please visit www.motorik-modul.de. Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2013; all rights reserved.

The Influence of Social Conditions Across the Life Course on the Human Gut Microbiota: A Pilot Project With the Wisconsin Longitudinal Study.

PubMed

Herd, Pamela; Schaeffer, Nora Cate; DiLoreto, Kerryann; Jacques, Karen; Stevenson, John; Rey, Federico; Roan, Carol

2017-12-15

To test the feasibility of collecting and integrating data on the gut microbiome into one of the most comprehensive longitudinal studies of aging and health, the Wisconsin Longitudinal Study (WLS). The long-term goal of this integration is to clarify the contribution of social conditions in shaping the composition of the gut microbiota late in life. Research on the microbiome, which is considered to be of parallel importance to human health as the human genome, has been hindered by human studies with nonrandomly selected samples and with limited data on social conditions over the life course. No existing population-based longitudinal study had collected fecal specimens. Consequently, we created an in-person protocol to collect stool specimens from a subgroup of WLS participants. We collected 429 stool specimens, yielding a 74% response rate and one of the largest human samples to date. The addition of data on the gut microbiome to the WLS-and to other population based longitudinal studies of aging-is feasible, under the right conditions, and can generate innovative research on the relationship between social conditions and the gut microbiome. © The Author 2017. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

A Longitudinal Investigation into L2 Learners' Cognitive Processes during Study Abroad

ERIC Educational Resources Information Center

Ren, Wei

2014-01-01

The present study longitudinally investigates the cognitive processes of advanced L2 learners engaged in a multimedia task that elicited status-equal and status-unequal refusals in English during their study abroad. Data were collected three times by retrospective verbal report from 20 Chinese learners who were studying abroad over the course of…

A Longitudinal Study of Junior High School Students' Conceptions of the Structure of Materials

ERIC Educational Resources Information Center

Margel, Hannah; Eylon, Bat-Sheva; Scherz, Zahava

2008-01-01

This longitudinal study investigated the progression in junior high school (JHS) students' conceptions of the structure of matter while studying a new instructional approach dealing with "Materials." In particular, we studied the progression of students' learning along two dimensions: (a) the conceptual model; and (b) the context of application.…

Social Class Differentiation in Cognitive Development: A Longitudinal Study.

ERIC Educational Resources Information Center

Golden, Mark; And Others

In an effort to isolate the emergence and causes of social class differences in intellectual performance, this longitudinal study was undertaken as a follow-up on a cross-sectional study that yielded no social class differences on the Cattell Infant Intelligence Scale for 12-, 18-, and 24-month-old black children. In the present study, 89 children…

A Longitudinal Study of Pubertal Timing and Extreme Body Change Behaviors among Adolescent Boys and Girls

ERIC Educational Resources Information Center

McCabe, Marita P.; Ricciardelli, Lina A.

2004-01-01

Recent studies have examined the prevalence of disordered eating and other health risk behaviors among adolescent boys and girls. However, these studies generally have not examined predictors of these behaviors, and have not embedded the investigations within a theoretical framework. This study employed a longitudinal design to evaluate the…

"Many Moons": Understanding Teacher Learning from a Teacher Education Perspective. Issue Paper 88-5.

ERIC Educational Resources Information Center

McDiarmid, G. Williamson; Ball, Deborah Loewenberg

The Teacher Education and Learning to Teach Study of the National Center for Research on Teacher Education combines case studies of teacher education programs with longitudinal studies of teacher learning. In this paper, the development of the theoretical framework on which instrumentation for the longitudinal study is based is discussed.…

A Longitudinal Study of Middle and Secondary Level Science Textbook Vocabulary Loads

ERIC Educational Resources Information Center

Groves, Fred H.

2016-01-01

Middle and secondary science textbooks have long been a primary support for instruction, often leading to heavy emphasis on domain-specific vocabulary. A longitudinal study was conducted to compare vocabulary loads of science textbooks published since 2010 to results of two previous studies going back to 1983. In each study, textbooks chosen…

Family and Psychosocial Risk Factors in a Longitudinal Epidemiological Study of Adolescents.

ERIC Educational Resources Information Center

Cuffe, Steven P.; McKeown, Robert E.; Addy, Cheryl L.; Garrison, Carol Z.

2005-01-01

Objective: To study the association of family and social risk factors with psychopathology in a longitudinal study of adolescents. Method: From 1986 to 1988, 3,419 seventh through ninth graders were screened with the Center for Epidemiologic Studies Depression Scale. The top decile scorers and a random sample of the remainder were interviewed…

A longitudinal analysis of the impact of childhood stress on weight status among Chinese youth.

PubMed

Tanenbaum, H C; Li, Y; Felicitas-Perkins, J Q; Zhang, M; Palmer, P; Johnson, C A; Xie, B

2017-05-01

Limited research has explored longitudinal impact of stress on negative health outcomes, including overweight and obesity in Asian societies. Using data from a longitudinal school-based health promotion study conducted in Wuhan, China from 1999 to 2004, this study investigated the longitudinal effects of childhood stress exposure, including stressors related to school, family, peers, violence and health on overweight, and obesity risk during the transition to adolescence among 2179 Chinese adolescents. Results showed that health stressors were consistently related to higher BMI Z score for both boys and girls baseline, it also predicted higher likelihood of overweight status over time for girls. This finding highlights a particularly challenging time period for girls, suggesting a particular challenging time they face at the intersection of puberty and demanding school environment.

Problematics of Time and Timing in the Longitudinal Study of Human Development: Theoretical and Methodological Issues

PubMed Central

Lerner, Richard M.; Schwartz, Seth J; Phelps, Erin

2009-01-01

Studying human development involves describing, explaining, and optimizing intraindividual change and interindividual differences in such change and, as such, requires longitudinal research. The selection of the appropriate type of longitudinal design requires selecting the option that best addresses the theoretical questions asked about developmental process and the use of appropriate statistical procedures to best exploit data derived from theory-predicated longitudinal research. This paper focuses on several interrelated problematics involving the treatment of time and the timing of observations that developmental scientists face in creating theory-design fit and in charting in change-sensitive ways developmental processes across life. We discuss ways in which these problematics may be addressed to advance theory-predicated understanding of the role of time in processes of individual development. PMID:19554215

Psychosocial work characteristics and sleep quality: a systematic review of longitudinal and intervention research.

PubMed

Van Laethem, Michelle; Beckers, Debby G J; Kompier, Michiel A J; Dijksterhuis, Ap; Geurts, Sabine A E

2013-11-01

The objective of this study was to review longitudinal and intervention studies examining the association between psychosocial work characteristics (eg, job demands, job control, and social support) and sleep quality. Our main research aims were to examine whether (i) psychosocial work characteristics are a predictor of sleep quality, and (ii) sleep quality, in turn, is a predictor of psychosocial work characteristics. A systematic literature search resulted in 20 relevant papers, of which 16 were longitudinal studies and 3 were intervention studies (1 study was discussed in separate papers). To quantify results, we assessed the strength of evidence of all examined associations and subsequently evaluated the studies' research quality based on predefined quality criteria. One intervention and three longitudinal studies studies were categorized as being of high-quality. In longitudinal studies, we found consistent and strong evidence for a negative relation between job demands and sleep quality as well as evidence for a positive relation between job control and sleep quality. Other psychosocial work characteristics were examined in an insufficient number of (high-quality) studies. Moreover, both intervention studies as well as studies investigating reversed and reciprocal relations are rare, which further limits the possibility of drawing conclusions on causality. Based on the current literature, it can be concluded that high job demands and low job control are predictors of poor sleep quality. More high-quality research is needed to examine the possible causal relationship between these and other psychosocial work characteristics with sleep quality, in addition to research focusing on reversed and reciprocal relations.

A Longitudinal Study of Motivation in Foreign and Second Language Learning Context

ERIC Educational Resources Information Center

Ordem, Eser

2017-01-01

Although motivation has been one of the most commonly studied subjects in second and foreign language learning in recent decades, it still remains an enigma for learners and teachers. This longitudinal study aimed to follow a student (N = 1) studying German in both second and foreign language environment for three years. The study was descriptive,…

Differences in Causal Estimates from Longitudinal Analyses of Residualized versus Simple Gain Scores: Contrasting Controls for Selection and Regression Artifacts

ERIC Educational Resources Information Center

Larzelere, Robert E.; Ferrer, Emilio; Kuhn, Brett R.; Danelia, Ketevan

2010-01-01

This study estimates the causal effects of six corrective actions for children's problem behaviors, comparing four types of longitudinal analyses that correct for pre-existing differences in a cohort of 1,464 4- and 5-year-olds from Canadian National Longitudinal Survey of Children and Youth (NLSCY) data. Analyses of residualized gain scores found…

The Meaningful Identity: A Longitudinal Look at the Interplay between Identity and Meaning in Life in Adolescence

ERIC Educational Resources Information Center

Negru-Subtirica, Oana; Pop, Eleonora Ioana; Luyckx, Koen; Dezutter, Jessie; Steger, Michael F.

2016-01-01

Identity formation in adolescence is closely linked to searching for and acquiring meaning in one's life. To date little is known about the manner in which these 2 constructs may be related in this developmental stage. In order to shed more light on their longitudinal links, we conducted a 3-wave longitudinal study, investigating how identity…

Effects of Maternal Parenting and Mother-Child Relationship Quality on Short-Term Longitudinal Change in Self-Regulation in Early Adolescence

ERIC Educational Resources Information Center

Moilanen, Kristin L.; Rambo-Hernandez, Karen E.

2017-01-01

The purpose of the present study was to explore the degree to which short-term longitudinal change in adolescent self-regulation was attributable to maternal parenting and mother-child relationship quality. A total of 821 mother-adolescent dyads provided data in the 1992 and 1994 waves of the Children of the National Longitudinal Survey of…

RECRUITMENT AND RETENTION ISSUES FOR A LARGE LONGITUDINAL STUDY OF CHILDREN'S ENVIRONMENTAL HEALTH

EPA Science Inventory

Recruitment and Retention Issues for a Large Longitudinal Study of Children's Environmental Health *D Lobdell, S Gilboa, P Mendola (US Environmental Protection Agency, Research Triangle Park, NC, 27711)

An understanding of the most effective recruitment techniques and rete...

A Longitudinal Study on Learner Career Advancement in MOOCs

ERIC Educational Resources Information Center

Wang, Yuan; Paquette, Luc; Baker, Ryan

2014-01-01

In this paper, we present progress towards a longitudinal study of the post-course career advancement of MOOC learners. We present initial results and analysis plans for how to link this to in-course behaviour, towards better understanding the goals of all MOOC learners.

RECRUITMENT AND RETENTION ISSUES FOR A LONGITUDINAL STUDY OF CHILDREN'S ENVIRONMENTAL HEALTH

EPA Science Inventory

A better understanding of the most effective recruitment techniques and retention strategies for longitudinal, community-based, children's environmental health studies is needed. A series of 18 focus groups were conducted across the U.S. in February 2003. Pregnant women and exp...

Sex Stratification, Technology and Organizational Change: A Longitudinal Case Study of AT&T.

ERIC Educational Resources Information Center

Hacker, Sally L.

1979-01-01

Recent technological displacement in AT&T affected workers differentially by sex. This longitudinal analysis of changes in AT&T's organizational structure addresses the tendency of organizational research to ignore the variable of sex in the study of change. (Author/RLV)

School Climate, Discrimination, and Depressive Symptoms among Asian American Adolescents

ERIC Educational Resources Information Center

Wang, Cixin; Atwal, Kavita

2015-01-01

The current study examined a multidimensional, developmental, and transactional model for depressive symptoms among Asian American adolescents using longitudinal data from 1,664 Asian American adolescents in the Children of Immigrants Longitudinal Study (CILS). Specifically, the relationships among school climate, acculturation, perceived…

Teacher Questionnaire [ETS Head Start Longitudinal Study].

ERIC Educational Resources Information Center

Educational Testing Service, Princeton, NJ.

This 147-item questionnaire was used to collect data on those Head Start and other preschool teachers who were teaching Longitudinal Study target children. Areas of requested information included: demographic characteristics, education and experience, attitudes toward minority-groups and economically disadvanted children's motivation and learning…

DEMONSTRATION OF LOW COST, LOW BURDEN EXPOSURE MONITORING STRATEGIES FOR USE IN LONGITUDINAL COHORT STUDIES

EPA Science Inventory

A large longitudinal cohort study designed to evaluate the association between children's exposures to environmental agents and health outcomes presents many challenges for exposure monitoring. Exposure of the child must be measured for multiple chemicals through multiple path...

An ultrastructural study of calcitonin gene-related peptide-immunoreactive nerve fibers innervating the rat posterior longitudinal ligament. A morphologic basis for their possible efferent actions.

PubMed

Imai, S; Konttinen, Y T; Tokunaga, Y; Maeda, T; Hukuda, S; Santavirta, S

1997-09-01

The present study investigated ultrastructural characteristics of calcitonin gene-related peptide-immunoreactive nerve fibers in the posterior longitudinal ligament of the rat lumbar spine. To provide a morphologic basis for assessment of the afferent and, in particular, efferent functions of calcitonin gene-related peptide immunoreactive nerves in the posterior longitudinal ligament and their eventual role in degenerative spondylarthropathies and low back pain. Previous studies using light-microscopic localization of sensory neuronal markers such as calcitonin gene-related peptide have reported the presence of sensory fibers in the supporting structures of the vertebral column. Meanwhile, accumulating research data have suggested efferent properties for calcitonin gene-related peptide, i.e., a trophic action that alters the intrinsic properties of target cells not through transient action of synaptic transmission, but through long-lasting signal transmission by the secreted neuropeptides. To verify such trophic, paracrine actions of the calcitonin gene-related peptide-containing fibers in the posterior longitudinal ligament, however, ultrastructural details of the terminals and their spatial relationship to their eventual target structures have to be elucidated. Rat posterior longitudinal ligaments were stained immunohistochemically for calcitonin gene-related peptide. Light-microscopic analysis of the semithin sections facilitated subsequent electron microscopy of specific sites of the posterior longitudinal ligament to determine ultrastructural details and nerve fiber-target relationships. The rat lumbar posterior longitudinal ligament was found to be innervated by two distinctive calcitonin gene-related peptide immunoreactive nerve networks. In immunoelectronmicroscopy, the fibers of the deep network had numerous free nerve endings, whereas those of the superficial network showed spatial associations with other non-calcitonin gene-related peptide immunoreactive components of the network. In both systems, naked axons not covered by the Schwann cells made close spatial contact with smooth muscle cells: of blood vessels and resident posterior longitudinal ligament fibroblasts. The ultrastructural characteristics of the innervation of the rat posterior longitudinal ligament would be compatible not only with a nociceptive function, but also with neuromodulatory, vasoregulatory, and trophic functions, as has already been established in some visceral organs.

Longitudinal Associations between Externalizing Behavior and Dysfunctional Eating Attitudes and Behaviors: A Community-Based Study

ERIC Educational Resources Information Center

Marmorstein, Naomi R.; von Ranson, Kristin M.; Iacono, William G.; Succop, Paul A.

2007-01-01

This study investigated longitudinal associations between externalizing behavior and dysfunctional eating attitudes and behaviors. Participants were girls drawn from the community-based Minnesota Twin Family Study and assessed at ages 11, 14, and 17. Cross-sectional correlations indicated that the strength of the associations between externalizing…

Prospective Prediction of Nonsuicidal Self-Injury: A 1-Year Longitudinal Study in Young Adults

ERIC Educational Resources Information Center

Glenn, Catherine R.; Klonsky, E. David

2011-01-01

Nonsuicidal self-injury (NSSI) has become a significant public health problem. Although numerous studies have examined cross-sectional psychological correlates of NSSI, there has been little research examining predictors of NSSI over time. The present study examined cross-sectional and longitudinal correlates of NSSI in 81 young adult…

Power of Models in Longitudinal Study: Findings from a Full-Crossed Simulation Design

ERIC Educational Resources Information Center

Fang, Hua; Brooks, Gordon P.; Rizzo, Maria L.; Espy, Kimberly Andrews; Barcikowski, Robert S.

2009-01-01

Because the power properties of traditional repeated measures and hierarchical multivariate linear models have not been clearly determined in the balanced design for longitudinal studies in the literature, the authors present a power comparison study of traditional repeated measures and hierarchical multivariate linear models under 3…

Individual Differences in Pronoun Reversal: Evidence from Two Longitudinal Case Studies

ERIC Educational Resources Information Center

Evans, Karen E.; Demuth, Katherine

2012-01-01

Pronoun reversal, the use of "you" for self-reference and "I" for an addressee, has often been associated with Autism Spectrum Disorder (ASD) and impaired language. However, recent case studies have shown the phenomenon also to occur in typically developing and even precocious talkers. This study examines longitudinal corpus data from two…

Continuing and Ceasing Leisure Activities in Later Life: A Longitudinal Study

ERIC Educational Resources Information Center

Strain, Laurel A.; Grabusic, Carmen C.; Searle, Mark S.; Dunn, Nicole J.

2002-01-01

Purpose: This study examined changes in leisure activities of older adults over an 8-year period, and associated sociodemographic and health characteristics. Design and Methods: Data were from a longitudinal study conducted in Winnipeg, Manitoba, Canada; 380 respondents were interviewed in-person in both 1985 and 1993. Changes in ten specific…

Language and Ageing--Exploring Propositional Density in Written Language--Stability over Time

ERIC Educational Resources Information Center

Spencer, Elizabeth; Craig, Hugh; Ferguson, Alison; Colyvas, Kim

2012-01-01

This study investigated the stability of propositional density (PD) in written texts, as this aspect of language shows promise as an indicator and as a predictor of language decline with ageing. This descriptive longitudinal study analysed written texts obtained from the Australian Longitudinal Study of Women's Health in which participants were…

Homeschooling Education: Longitudinal Study of Methods, Materials, and Curricula

ERIC Educational Resources Information Center

Hanna, Linda G.

2012-01-01

In a comprehensive study of two-hundred fifty homeschooling families in urban, rural and suburban areas of the Commonwealth of Pennsylvania, the researcher examined all aspects of the instruction, materials and curricula employed by the families in a ten-year longitudinal study from 1998 through 2008. The researcher conducted interviews and…

PRELIMINARY PARTICULATE MATTER MASS CONCENTRATIONS ASSOCIATED WITH LONGITUDINAL PANEL STUDIES "ASSESSING HUMAN EXPOSURES OF HIGH RISK SUBPOPULATIONS TO PARTICULATE MATTER"

EPA Science Inventory

The NERL Particulate Matter Longitudinal Panel Studies were used to characterize temporal variations of personal exposure to PM and related co-pollutants, including that of PM measured at ambient sites. These studies were fundamental in understanding the associations between p...

A Longitudinal Study of the Correlates of Children's Social Behavior.

ERIC Educational Resources Information Center

Feldhusen, John F.; And Others

Reported was an 8 year longitudinal study of social and antisocial behavioral correlates in 1550 third, sixth, and ninth grade children identified as either aggressive-disruptive or prosocial by their teachers. A more intensive study was made of 192 aggressive-disruptive and 192 prosocial children. Data included interviews, individual tests (such…

The Need for Large-Scale, Longitudinal Empirical Studies in Middle Level Education Research

ERIC Educational Resources Information Center

Mertens, Steven B.; Caskey, Micki M.; Flowers, Nancy

2016-01-01

This essay describes and discusses the ongoing need for large-scale, longitudinal, empirical research studies focused on middle grades education. After a statement of the problem and concerns, the essay describes and critiques several prior middle grades efforts and research studies. Recommendations for future research efforts to inform policy…

Investigating Sexual Abuse: Findings of a 15-Year Longitudinal Study

ERIC Educational Resources Information Center

McCormack, Bob; Kavanagh, Denise; Caffrey, Shay; Power, Anne

2005-01-01

Background: There is a lack of longitudinal large-scale studies of sexual abuse in intellectual disability services. Such studies offer opportunities to examine patterns in disclosure, investigation and outcomes, and to report on incidence and trends. Methods: All allegations of sexual abuse (n = 250) involving service users as victims or…

Latino Parental Involvement in Kindergarten: Findings from the Early Childhood Longitudinal Study

ERIC Educational Resources Information Center

Durand, Tina M.

2011-01-01

Parental involvement in children's schooling is an important component of children's early school success. Few studies have examined this construct exclusively among Latino families. Using data from the Early Childhood Longitudinal Study (ECLS-K), the present investigation (N = 2,051) explored relations between Latino parents' home and school…

Positive Socialization Mechanisms in Secure and Insecure Parent-Child Dyads: Two Longitudinal Studies

ERIC Educational Resources Information Center

Kochanska, Grazyna; Woodard, Jarilyn; Kim, Sanghag; Koenig, Jamie L.; Yoon, Jeung Eun; Barry, Robin A.

2010-01-01

Background: Implications of early attachment have been extensively studied, but little is known about its long-term indirect sequelae, where early security organization moderates future parent-child relationships, serving as a catalyst for adaptive and maladaptive processes. Two longitudinal multi-trait multi-method studies examined whether early…

A Longitudinal Investigation of Project-Based Instruction and Student Achievement in High School Social Studies

ERIC Educational Resources Information Center

Summers, Emily J.; Dickinson, Gail

2012-01-01

This longitudinal study focused on how project-based instruction (PBI) influenced secondary social studies students' academic achievement and promoted College and Career Readiness (CCR). We explored and compared student achievement in a PBI high school versus a traditional instruction high school within the same rural school district. While…

A Longitudinal Study of Judge Leniency and Consistency.

ERIC Educational Resources Information Center

Lunz, Mary E.; O'Neill, Thomas R.

This retrospective longitudinal study was designed to show grading leniency patterns of judges within and across clinical examination administrations. Data from 17 different administrations of the histology examination of the American Society of Clinical Pathologists over 10 years were studied. Over the 10 years there were 4,683 candidates and 57…

Preparing the Next Generation for Electoral Engagement: Social Studies and the School Context

ERIC Educational Resources Information Center

Callahan, Rebecca M.; Muller, Chandra; Schiller, Kathryn S.

2010-01-01

In an era of accountability focused primarily on academic outcomes, it may be useful to reconsider the other original aim of U.S. schools: citizenship development. Using longitudinal, nationally representative data (Adolescent Health and Academic Achievement Study [AHAA] and the National Longitudinal Study of Adolescent Health [Add Health]), we…

How Teachers' Self-Efficacy Is Related to Instructional Quality: A Longitudinal Analysis

ERIC Educational Resources Information Center

Holzberger, Doris; Philipp, Anja; Kunter, Mareike

2013-01-01

This study extends previous research on teachers' self-efficacy by exploring reciprocal effects of teachers' self-efficacy and instructional quality in a longitudinal panel study. The study design combined a self-report measure of teacher self-efficacy with teacher and student ratings of instructional quality (assessing cognitive activation,…

Impaired Perception of Syllable Stress in Children with Dyslexia: A Longitudinal Study

ERIC Educational Resources Information Center

Goswami, Usha; Mead, Natasha; Fosker, Tim; Huss, Martina; Barnes, Lisa; Leong, Victoria

2013-01-01

Prosodic patterning is a key structural element of spoken language. However, the potential role of prosodic awareness in the phonological difficulties that characterise children with developmental dyslexia has been little studied. Here we report the first longitudinal study of sensitivity to syllable stress in children with dyslexia, enabling the…

Lewis Terman: Genetic Study of Genius--Elementary School Students

ERIC Educational Resources Information Center

Jolly, Jennifer L.

2008-01-01

Although the field of gifted education generally recognizes the foundational work of Lewis Terman, rarely does one stop to examine the details of his longitudinal study and their connection to present-day gifted education. This article reexamines the beginnings of Terman's longitudinal study with a focus on elementary-school-aged children.…

THE INFLUENCE OF PARTICULATE MATTER OF AMBIENT ORIGIN UPON INDOOR RESIDENTIAL MASS CONCENTRATIONS INVOLVING SENSITIVE SUBPOPULATIONS-RESULTS FROM LONGITUDINAL PANEL STUDIES

EPA Science Inventory

The US EPA has completed field data collections from a series of longitudinal particulate matter (PM) exposure panel field studies. These studies were conducted in Baltimore, Maryland (1998), Fresno, California (1999), and Research Triangle Park (RTP), North Carolina (2000-2001) ...

Conditions for Ubiquitous Computing: What Can Be Learned from a Longitudinal Study

ERIC Educational Resources Information Center

Lei, Jing

2010-01-01

Based on survey data and interview data collected over four academic years, this longitudinal study examined how a ubiquitous computing project evolved along with the changes in teachers, students, the human infrastructure, and technology infrastructure in the school. This study also investigated what conditions were necessary for successful…

Longitudinal Study of Low and High Achievers in Early Mathematics

ERIC Educational Resources Information Center

Navarro, Jose I.; Aguilar, Manuel; Marchena, Esperanza; Ruiz, Gonzalo; Menacho, Inmaculada; Van Luit, Johannes E. H.

2012-01-01

Background: Longitudinal studies allow us to identify, which specific maths skills are weak in young children, and whether there is a continuing weakness in these areas throughout their school years. Aims: This 2-year study investigated whether certain socio-demographic variables affect early mathematical competency in children aged 5-7 years.…

A Longitudinal Study of School Districts' Sustained Improvement

ERIC Educational Resources Information Center

Sampson, Pauline M.

2011-01-01

In this longitudinal study of one region in the state of Texas, there was an examination of district leadership and the sustaining of high student achievement for their districts. The results of this study suggest that sustained improvement of student achievement is very difficult. The districts that had sustained improvement had stable district…

Evidence for a General ADHD Factor from a Longitudinal General School Population Study

ERIC Educational Resources Information Center

Normand, Sebastien; Flora, David B.; Toplak, Maggie E.; Tannock, Rosemary

2012-01-01

Recent factor analytic studies in Attention-Deficit/Hyperactivity Disorder (ADHD) have shown that hierarchical models provide a better fit of ADHD symptoms than correlated models. A hierarchical model includes a general ADHD factor and specific factors for inattention, and hyperactivity/impulsivity. The aim of this 12-month longitudinal study was…

Longitudinal Comparison between Male and Female Preschool Children with Autism Spectrum Disorder

ERIC Educational Resources Information Center

Postorino, Valentina; Fatta, Laura Maria; De Peppo, Lavinia; Giovagnoli, Giulia; Armando, Marco; Vicari, Stefano; Mazzone, Luigi

2015-01-01

Epidemiological studies have highlighted a strong male bias in autism spectrum disorder (ASD), however few studies have examined gender differences in autism symptoms, and available findings are inconsistent. The aim of the present study is to investigate the longitudinal gender differences in developmental profiles of 30 female and 30 male…

National Longitudinal Transition Study 2012: Design Documentation. NCEE 2017-4021

ERIC Educational Resources Information Center

Burghardt, John; Haimson, Joshua; Lipscomb, Stephen; Liu, Albert Y.; Potter, Frank; Waits, Tiffany; Wang, Sheng

2017-01-01

The National Longitudinal Transition Study 2012 (NLTS 2012) is the third in the series of NLTS studies sponsored by the U.S. Department of Education to examine youth with disabilities receiving services under the Individuals with Disabilities Education Act (IDEA), a long-standing federal law last updated in 2004. Under IDEA, youth with…

State and Local Implementation of the "No Child Left Behind Act." Volume III--Accountability under "NCLB" Interim Report

ERIC Educational Resources Information Center

Le Floch, Kerstin Carlson; Martinez, Felipe; O'Day, Jennifer; Stecher, Brian; Taylor, James; Cook, Andrea

2007-01-01

This report presents findings about accountability from two longitudinal studies, the National Longitudinal Study of "No Child Left Behind" (NLS-"NCLB"), and the Study of State Implementation of Accountability and Teacher Quality Under "No Child Left Behind" (SSI-"NCLB"). The research teams for these two…

Social Class and Japanese Mothers' Support of Young Children's Education: A Qualitative Study

ERIC Educational Resources Information Center

Yamamoto, Yoko

2015-01-01

The impact of social class backgrounds on young children's educational experiences has attracted increasing attention in early childhood research. However, few longitudinal studies related to social class and parental involvement in young children's education are available, especially in East Asian contexts. In this longitudinal qualitative study,…

Emotional and Behavioural Problems in the Context of Cyberbullying: A Longitudinal Study among German Adolescents

ERIC Educational Resources Information Center

Schultze-Krumbholz, Anja; Jakel, Anne; Schultze, Martin; Scheithauer, Herbert

2012-01-01

Although many studies have reported on internalising and externalising problems related to cyberbullying roles, there is a lack of longitudinal research in this area. This study reports (1) cross-sectional data from 412 German middle-school students to examine differences between cyberbullies, cybervictims and cyberbully-victims compared to…

Rehabitilation and extension of a khettara for a sustainable use of underground water resources

NASA Astrophysics Data System (ADS)

Pilia, A.; Spanu, V.; Concollato, C.; Calzolai, E.; Valenilla, A. M.

2009-04-01

As one of the major effects of soil degradation resulting from antropogenic factors and influenced by climate variations, desertification represents a significant environmental issue in arid and semi-arid areas. Owing to a lack of resources to tackle the problem, the consequences of desertification drastically affect the population of developing countries. One of the areas affected by this problem is the desert area of Hassi Labiad, near to Merzouga, in the South- East of Morocco, close to the border with Algeria, where the Erg Chebbi desert begins. From a geological point of view the studied zone extends across coarse sand dunes from Quaternary (Erg Chebbi Desert), which lies on a basement constituted by clay schist with sandstone intercalations and mauve- grayish sandstone from Lower Viséen (Carboniferous). Basement outcrops are identified in the area. In this area, the hydrological supply has been guaranteed for thousands of years by an ancient irrigation system, used in these area since about 1000 BC, the so called khettara. This system, from its creation by the Persians, has been diffused across the whole arabic culture; it's based on the picking up of water through underground draining channels from shallow acquifers with an altitude above sea level, which are higher than the irrigation areas to which water is brought. This system worked until a few years ago when, due to touristic development in the area, many groundwater pumping wells were created; the overpumping caused the decrease of groundwater level. Therefore, there was no more intersection between the khettara channel and the aquifer; and it became necessary to find a new intersection point by prolongating the ketthara principal channel. This project has been promoted and directed by the UNDP, the local ONG AHT Hassi Labiad in collaboration with Bambini nel Deserto NGO, and Osservatorio Mediterraneo Onlus. Basically, it consisted of a hydrogeological study in order to check the feasibility of the extension and the optimal peculiarities for the new channelling, for a sustainable use of underground water resources. The methodology consisted principally of topographic and water level measurements through wells and piezometers. Most of these measurements were made in water wells that already exist, due to the existence of the old khettara, while in the areas where enough density of measurement points is not found, new piezometres have been realised. Moreover, an analysis of rain gauge data and a valuation of the quantity of the underground water taken from the system have been carried out, in order to make a first hydrogeological balance. From the achieved results with the hydrogeological study an extension of the khettara of 230 m with a E-W direction has been made, that allowed to reintercept the alluvial ground water and to create a drainage system able to pick up the underground water in a sustainable way, also during the driest period of the year. Work carried out with a Bambini nel Deserto project, with the financial support of UNDP, the local ONG AHT Hassi Labiad in collaboration with Osservatorio Mediterraneo Onlus.

Longitudinal Analysis of Academic Burnout in Korean Middle School Students.

PubMed

Kim, Boyoung; Lee, Minyoung; Kim, Keunhwa; Choi, Hyunju; Lee, Sang Min

2015-10-01

The purpose of the study was to investigate the longitudinal relationships between the initial values and slopes of three dimensions of burnout syndrome (i.e. emotional exhaustion, cynicism and academic inefficacy). The study utilized four-wave longitudinal data from a total of 367 (81.6% response rate) middle school students in South Korea. Comprising a 6-month interval survey, the first survey was conducted in June 2010, the second in December 2010, the third in June 2011 and the fourth in December 2011. All participants were 13-year-olds at the first and second surveys, and 14-year-olds at the third and fourth surveys. The Maslach Burnout Inventory-Student Survey was used for each survey to assess the level of academic burnout. The longitudinal data were analysed using latent growth modelling. The results of the study indicated that high initial values (intercept) for emotional exhaustion were associated with a higher rate of increase (slope) in cynicism and academic inefficacy. On the other hand, high initial values for cynicism and academic inefficacy were associated with a lower rate of increase in the other dimensions. This longitudinal study should promote understanding of burned-out students and contribute to the literature by informing the design of prevention programmes for academic burnout. Copyright © 2014 John Wiley & Sons, Ltd.

Tracking brain damage in progressive supranuclear palsy: a longitudinal MRI study.

PubMed

Agosta, Federica; Caso, Francesca; Ječmenica-Lukić, Milica; Petrović, Igor N; Valsasina, Paola; Meani, Alessandro; Copetti, Massimiliano; Kostić, Vladimir S; Filippi, Massimo

2018-01-18

In this prospective, longitudinal, multiparametric MRI study, we investigated clinical as well as brain grey matter and white matter (WM) regional changes in patients with progressive supranuclear palsy-Richardson's syndrome (PSP-RS). Twenty-one patients with PSP-RS were evaluated at baseline relative to 36 healthy controls and after a mean follow-up of 1.4 years with clinical rating scales, neuropsychological tests and MRI scans. Relative to controls, patients with PSP-RS showed at baseline a typical pattern of brain damage, including midbrain atrophy, frontal cortical thinning and widespread WM involvement of the main infratentorial and supratentorial tracts that exceeded cortical damage. Longitudinal study showed that PSP-RS exhibited no further changes in cortical thinning, which remained relatively focal, while midbrain atrophy and WM damage significantly progressed. Corpus callosum and frontal WM tract changes correlated with the progression of both disease severity and behavioural dysfunction. This study demonstrated the feasibility of carrying out longitudinal diffusion tensor MRI in patients with PSP-RS and its sensitivity to identifying the progression of pathology. Longitudinal midbrain volume loss and WM changes are associated with PSP disease course. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Longitudinal Study of Body Mass Index in Young Males and the Transition to Fatherhood

PubMed Central

Garfield, Craig F.; Duncan, Greg; Gutina, Anna; Rutsohn, Joshua; McDade, Thomas W.; Adam, Emma K.; Coley, Rebekah Levine; Chase-Lansdale, P. Lindsay

2017-01-01

Despite a growing understanding that the social determinants of health have an impact on body mass index (BMI), the role of fatherhood on young men’s BMI is understudied. This longitudinal study examines BMI in young men over time as they transition from adolescence into fatherhood in a nationally representative sample. Data from all four waves of the National Longitudinal Study of Adolescent Health supported a 20-year longitudinal analysis of 10,253 men beginning in 1994. A “fatherhood-year” data set was created and changes in BMI were examined based on fatherhood status (nonfather, nonresident father, resident father), fatherhood years, and covariates. Though age is positively associated with BMI over all years for all men, comparing nonresident and resident fathers with nonfathers reveals different trajectories based on fatherhood status. Entrance into fatherhood is associated with an increase in BMI trajectory for both nonresident and resident fathers, while nonfathers exhibit a decrease over the same period. In this longitudinal, population-based study, fatherhood and residence status play a role in men’s BMI. Designing obesity prevention interventions for young men that begin in adolescence and carry through young adulthood should target the distinctive needs of these populations, potentially improving their health outcomes. PMID:26198724

Optimising qualitative longitudinal analysis: Insights from a study of traumatic brain injury recovery and adaptation.

PubMed

Fadyl, Joanna K; Channon, Alexis; Theadom, Alice; McPherson, Kathryn M

2017-04-01

Knowledge about aspects that influence recovery and adaptation in the postacute phase of disabling health events is key to understanding how best to provide appropriate rehabilitation and health services. Qualitative longitudinal research makes it possible to look for patterns, key time points and critical moments that could be vital for interventions and supports. However, strategies that support robust data management and analysis for longitudinal qualitative research in health-care are not well documented in the literature. This article reviews three challenges encountered in a large longitudinal qualitative descriptive study about experiences of recovery and adaptation after traumatic brain injury in New Zealand, and the strategies and technologies used to address them. These were (i) tracking coding and analysis decisions during an extended analysis period; (ii) navigating interpretations over time and in response to new data; and (iii) exploiting data volume and complexity. Concept mapping during coding review, a considered combination of information technologies, employing both cross-sectional and narrative analysis, and an expectation that subanalyses would be required for key topics helped us manage the study in a way that facilitated useful and novel insights. These strategies could be applied in other qualitative longitudinal studies in healthcare inquiry to optimise data analysis and stimulate important insights. © 2016 John Wiley & Sons Ltd.

Flowing together: a longitudinal study of collective efficacy and collective flow among workgroups.

PubMed

Salanova, Marisa; Rodríguez-Sánchez, Alma M; Schaufeli, Wilmar B; Cifre, Eva

2014-01-01

The aim of this study is to extend the Channel Model of Flow (Csikszentmihalyi, 1975, 1990) at the collective level (workgroups) by including collective efficacy beliefs as a predictor of collective flow based on the Social Cognitive Theory (Bandura, 1997, 2001). A two-wave longitudinal lab study was conducted with 250 participants working in 52 small groups. Longitudinal results from Structural Equation Modeling with data aggregated at the group level showed, as expected, that collective efficacy beliefs predict collective flow over time, both being related reciprocally. Findings and their theoretical and practical implications in the light of Social Cognitive Theory are discussed.

[The clinical effect and disquisition of anterior cervical approach surgery with posterior longitudinal ligament hook pliers and posterior longitudinal ligament nip pliers].

PubMed

Kuang, Ling-hao; Xu, Dong; Sun, Ya-wei; Cong, Jie; Tian, Ji-wei; Wang, Lei

2010-09-21

To study the clinical effect of anterior cervical approach surgery to removal posterior longitudinal ligament (PLL) with posterior longitudinal ligament hook pliers and posterior longitudinal ligament nip pliers. To retrospectively analyzed anterior cervical approach surgery treatment 73 patients who were cervical spondylosis myelopathy. All patients removal PLL with self-make instrument, According to JOA grade to evaluate effect of operations. Full patients removal PLL were in succeed, in shape of extradural has renew, the JOA grade were increase, (12.8 ± 3.2) vs (8.3 ± 1.9). Removal PLL were increase effect of downright decompress in anterior cervical approach surgery, Operations become safety agile and reduce the complications with self-make instrument.

Immersion angle dependence of the resonant-frequency shift of the quartz crystal microbalance in a liquid: effects of longitudinal wave.

PubMed

Yoshimoto, Minoru; Kobirata, Satoshi; Aizawa, Hideo; Kurosawa, Shigeru

2007-06-19

We investigated the effects of the longitudinal wave on the immersion angle dependence of the resonant-frequency shift, deltaF, of the quartz crystal microbalance, QCM. In order to study exactly the effects, we employed the three types of cells: normal cell, cell with the glass beads and cell with sponge. The longitudinal wave exists in the normal cell. On the other hand, both the cell with the glass beads and the cell with sponge eliminate the longitudinal wave. As results, we have found that the tendencies of deltaF are the same in the three types of cells. That is, we conclude that the longitudinal wave does not have effects on the immersion angle dependence of deltaF.

LONGITUDINAL STUDY OF SEMEN QUALITY AFTER INTERMITTENT EXPOSURE TO AIR POLLUTION

EPA Science Inventory

LONGITUDINAL STUDY OF SEMEN QUALITY AFTER INTERMITTENT EXPOSURE TO AIR POLLUTION. J. Rubes*, D. Zudova*, Veterinary Research Institute, Brno, CR, S.G. Selevan*, US EPA/ORD/NCEA, Washington, DC, D.P. Evenson, South Dakota State University, Brookings, SD, and S.D. Perreault, US ...

Health Benefits of Volunteering in the Wisconsin Longitudinal Study

ERIC Educational Resources Information Center

Piliavin, Jane Allyn; Siegl, Erica

2007-01-01

We investigate positive effects of volunteering on psychological well-being and self-reported health using all four waves of the Wisconsin Longitudinal Study. Confirming previous research, volunteering was positively related to both outcome variables. Both consistency of volunteering over time and diversity of participation are significantly…

A Method For The Longitudinal Study Of Behavioral Development In Infants And Children: The Early Development Of XXY Children

ERIC Educational Resources Information Center

Walzer, Stanley; And Others

1978-01-01

This report summarizes preliminary results from a behavioral study of 13 male infants who were ascertained to have an XX Y sex chromosome complement at birth and who are being followed longitudinally through early ontogenesis. (CM)

A Longitudinal Study of the Talent Search Program

ERIC Educational Resources Information Center

Brewer, Ernest W.; Landers, Jama McMahan

2005-01-01

This longitudinal study examined the impact of participation in the federally funded Talent Search program at The University of Tennessee, Knoxville. The Talent Search program provides career exploration and counseling services to low-income students with the potential to be first-generation college graduates. Postsecondary education enrollment…

Sport Involvement and Educational Outcomes of High School Students: A Longitudinal Study

ERIC Educational Resources Information Center

Hwang, Seunghyun; Feltz, Deborah L.; Kietzmann, Laura A.; Diemer, Matthew A.

2016-01-01

This study examined the relations among sport involvement and social and personal influences on high school students' educational expectations and attainment, using National Education Longitudinal Survey-88. Athletic engagement, educational expectations of significant others, peer support for academics, parental involvement in academics, and…

Flexitime in an Army Medical Center.

DTIC Science & Technology

1981-04-01

and Costigan (1973) conducted a longitudinal study of employee responses to the four day week in a medium-sized pharmaceutical company. The patterns...New York, New York, 1979. Nord, W.R. and Costigan, R. Worker adjustment to the four - day week : a longitudinal study. Journal of Applied Psychology, 58

Individual and Environmental Characteristics Associated with Cognitive Development in Down Syndrome: A Longitudinal Study

ERIC Educational Resources Information Center

Couzens, Donna; Haynes, Michele; Cuskelly, Monica

2012-01-01

Background: Associations among cognitive development and intrapersonal and environmental characteristics were investigated for 89 longitudinal study participants with Down syndrome to understand developmental patterns associated with cognitive strengths and weaknesses. Materials and Methods: Subtest scores of the Stanford-Binet IV collected…

On the confounds among retest gains and age-cohort differences in the estimation of within-person change in longitudinal studies: a simulation study.

PubMed

Hoffman, Lesa; Hofer, Scott M; Sliwinski, Martin J

2011-12-01

Although longitudinal designs are the only way in which age changes can be directly observed, a recurrent criticism involves to what extent retest effects may downwardly bias estimates of true age-related cognitive change. Considerable attention has been given to the problem of retest effects within mixed effects models that include separate parameters for longitudinal change over time (usually specified as a function of age) and for the impact of retest (specified as a function of number of exposures). Because time (i.e., intervals between assessment) and number of exposures are highly correlated (and are perfectly correlated in equal interval designs) in most longitudinal studies, the separation of effects of within-person change from effects of retest gains is only possible given certain assumptions (e.g., age convergence). To the extent that cross-sectional and longitudinal effects of age differ, obtained estimates of aging and retest may not be informative. The current simulation study investigated the recovery of within-person change (i.e., aging) and retest effects from repeated cognitive testing as a function of number of waves, age range at baseline, and size and direction of age-cohort differences on the intercept and age slope in age-based models of change. Significant bias and Type I error rates in the estimated effects of retest were observed when these convergence assumptions were not met. These simulation results suggest that retest effects may not be distinguishable from effects of aging-related change and age-cohort differences in typical long-term traditional longitudinal designs.

Study of the longitudinal space charge compensation and longitudinal instability of the ferrite inductive inserts in the Los Alamos Proton Storage Ring

NASA Astrophysics Data System (ADS)

Beltran, Chris

Future high intensity synchrotrons will have a large space charge effect. It has been demonstrated in the Proton Storage Ring (PSR) at the Los Alamos National Laboratory (LANL) that ferrite inductive inserts can be used to compensate for the longitudinal space charge effect. However, simply installing ferrite inductors in the PSR led to longitudinal instabilities that were not tolerable. It was proposed that heating the ferrite would change the material properties in such a way as to reduce the instability. This proposal was tested in the PSR, and found to be true. This dissertation investigates and describes the complex permeability of the ferrite at room temperature and at an elevated temperature. The derived complex permeability is then used to obtain an impedance at the two temperatures. The impedance is used to determine the amount of space charge compensation supplied by the inductors and predict the growth time and frequency range of the longitudinal instability. The impedance is verified by comparing the experimental growth time and frequency range of the longitudinal instability to theoretical and computer simulated growth times and frequency ranges of the longitudinal instability. Lastly, an approach to mitigating the longitudinal instability that does not involve heating the ferrite is explored.

Longitudinal dependence of the seasonal variations of the topside ionospheric and plasmaspheric electron content: observations and model results

NASA Astrophysics Data System (ADS)

Zhang, Man-Lian; Liu, Libo; Ning, Baiqi; Wan, Weixing

2016-07-01

Radio signals transmitted from GPS satellite going through the ionization zone above the Earth will be refracted by the ionized components in the ionosphere and the plasmasphere, which would produce additional transfer delay and generate extra errors in satellite navigation and positioning, etc. These errors have strong relation with the total electron content (TEC) along the signal's travelling path. Therefore TEC is one of the most important parameters required by many users for different modern usage purposes. The topside ionospheric and plasmaspheric electron content makes a large contribution to TEC. In the present study, data for the year 2008 of the topside ionospheric and plasmaspheric electron content (PEC) between the height of 800-20200km above the Earth derived from the upward-looking TEC measurements of the precise orbit determination antenna on board the COSMIC low Earth orbit (LEO) satellites to the GPS signals are used to study the longitudinal dependence of the seasonal variations of PEC. A comparison study of the observed PEC with the IZMIRAN_Plas model results is also made. Our study showed that PEC shows different seasonal variations at different longitudinal sectors: for the 240°E-60°E longitudinal sector, PEC shows a strong annual variation with lowest value in the June solstice and highest value in the December solstice months; In contrast, very weak seasonal variations are observed for PEC at 60°E-240°E longitudinal sector; Comparison study showed that this longitudinal dependence feature of the observed PEC's seasonal variation is not well captured by the IZMIRAN_Plas model result. Acknowledgments This research was supported by the National Natural Science Foundation of China (NSFC No. 41274163)

Sample size determination for mediation analysis of longitudinal data.

PubMed

Pan, Haitao; Liu, Suyu; Miao, Danmin; Yuan, Ying

2018-03-27

Sample size planning for longitudinal data is crucial when designing mediation studies because sufficient statistical power is not only required in grant applications and peer-reviewed publications, but is essential to reliable research results. However, sample size determination is not straightforward for mediation analysis of longitudinal design. To facilitate planning the sample size for longitudinal mediation studies with a multilevel mediation model, this article provides the sample size required to achieve 80% power by simulations under various sizes of the mediation effect, within-subject correlations and numbers of repeated measures. The sample size calculation is based on three commonly used mediation tests: Sobel's method, distribution of product method and the bootstrap method. Among the three methods of testing the mediation effects, Sobel's method required the largest sample size to achieve 80% power. Bootstrapping and the distribution of the product method performed similarly and were more powerful than Sobel's method, as reflected by the relatively smaller sample sizes. For all three methods, the sample size required to achieve 80% power depended on the value of the ICC (i.e., within-subject correlation). A larger value of ICC typically required a larger sample size to achieve 80% power. Simulation results also illustrated the advantage of the longitudinal study design. The sample size tables for most encountered scenarios in practice have also been published for convenient use. Extensive simulations study showed that the distribution of the product method and bootstrapping method have superior performance to the Sobel's method, but the product method was recommended to use in practice in terms of less computation time load compared to the bootstrapping method. A R package has been developed for the product method of sample size determination in mediation longitudinal study design.

Estimating correlation between multivariate longitudinal data in the presence of heterogeneity.

PubMed

Gao, Feng; Philip Miller, J; Xiong, Chengjie; Luo, Jingqin; Beiser, Julia A; Chen, Ling; Gordon, Mae O

2017-08-17

Estimating correlation coefficients among outcomes is one of the most important analytical tasks in epidemiological and clinical research. Availability of multivariate longitudinal data presents a unique opportunity to assess joint evolution of outcomes over time. Bivariate linear mixed model (BLMM) provides a versatile tool with regard to assessing correlation. However, BLMMs often assume that all individuals are drawn from a single homogenous population where the individual trajectories are distributed smoothly around population average. Using longitudinal mean deviation (MD) and visual acuity (VA) from the Ocular Hypertension Treatment Study (OHTS), we demonstrated strategies to better understand the correlation between multivariate longitudinal data in the presence of potential heterogeneity. Conditional correlation (i.e., marginal correlation given random effects) was calculated to describe how the association between longitudinal outcomes evolved over time within specific subpopulation. The impact of heterogeneity on correlation was also assessed by simulated data. There was a significant positive correlation in both random intercepts (ρ = 0.278, 95% CI: 0.121-0.420) and random slopes (ρ = 0.579, 95% CI: 0.349-0.810) between longitudinal MD and VA, and the strength of correlation constantly increased over time. However, conditional correlation and simulation studies revealed that the correlation was induced primarily by participants with rapid deteriorating MD who only accounted for a small fraction of total samples. Conditional correlation given random effects provides a robust estimate to describe the correlation between multivariate longitudinal data in the presence of unobserved heterogeneity (NCT00000125).

A novel pattern of longitudinal muscle contraction with subthreshold pharyngeal stimulus: a possible mechanism of lower esophageal sphincter relaxation

PubMed Central

Leslie, Eric; Bhargava, Valmik

2012-01-01

A subthreshold pharyngeal stimulus induces lower esophageal sphincter (LES) relaxation and inhibits progression of ongoing peristaltic contraction in the esophagus. Recent studies show that longitudinal muscle contraction of the esophagus may play a role in LES relaxation. Our goal was to determine whether a subthreshold pharyngeal stimulus induces contraction of the longitudinal muscle of the esophagus and to determine the nature of this contraction. Studies were conducted in 16 healthy subjects. High resolution manometry (HRM) recorded pressures, and high frequency intraluminal ultrasound (HFIUS) images recorded longitudinal muscle contraction at various locations in the esophagus. Subthreshold pharyngeal stimulation was induced by injection of minute amounts of water in the pharynx. A subthreshold pharyngeal stimulus induced strong contraction and caudal descent of the upper esophageal sphincter (UES) along with relaxation of the LES. HFIUS identified longitudinal muscle contraction of the proximal (3–5 cm below the UES) but not the distal esophagus. Pharyngeal stimulus, following a dry swallow, blocked the progression of dry swallow-induced peristalsis; this was also associated with UES contraction and descent along with the contraction of longitudinal muscle of the proximal esophagus. We identify a unique pattern of longitudinal muscle contraction of the proximal esophagus in response to subthreshold pharyngeal stimulus, which we propose may be responsible for relaxation of the distal esophagus and LES through the stretch sensitive activation of myenteric inhibitory motor neurons. PMID:22173917

Thermal study of longitudinal and torsional ultrasound phacoemulsification: tracking the temperature of the corneal surface, incision, and handpiece.

PubMed

Jun, Bokkwan; Berdahl, John P; Kim, Terry

2010-05-01

To evaluate the change and difference in the corneal surface, incision, and handpiece temperatures during longitudinal and torsional ultrasound (US) phacoemulsification with standard incisions (2.75 mm) and microincisions (2.20 mm) and the thermal effect on wounds. Department of Ophthalmology, Duke University, Durham, North Carolina, USA. In this prospective study, human cadaver eyes had simulated phacoemulsification. Group 1 had a 2.75 mm incision with 100% longitudinal US; Group 2, a 2.20 mm incision with 100% longitudinal US; Group 3, a 2.75 mm incision with 100% torsional US; and Group 4, a 2.20 mm incision with 100% torsional US. During phacoemulsification, the corneal incision was evaluated by surgical microscopy and scanning electron microscopy (SEM) and images of the corneal surface, incision, and handpiece were captured with an infrared camera. Twelve eyes (3 each group) were evaluated. The maximum incision temperature was higher in the longitudinal groups than in the torsional groups. With the same US modality, the maximum microincision temperature was higher than the maximum standard incision temperature. After application of full power for 40 seconds, wound burn was observed in all eyes in the longitudinal groups and no eyes in the torsional groups. On SEM, there was more extensive loss of Descemet membrane in the longitudinal groups than in the torsional groups. Incision temperature was influenced by US modality and was significantly lower with torsional US than with longitudinal US. Using torsional US with smaller incisions may decrease the risk for wound burn in eyes with denser cataracts. (c) 2010 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

A longitudinal model for functional connectivity networks using resting-state fMRI.

PubMed

Hart, Brian; Cribben, Ivor; Fiecas, Mark

2018-06-04

Many neuroimaging studies collect functional magnetic resonance imaging (fMRI) data in a longitudinal manner. However, the current fMRI literature lacks a general framework for analyzing functional connectivity (FC) networks in fMRI data obtained from a longitudinal study. In this work, we build a novel longitudinal FC model using a variance components approach. First, for all subjects' visits, we account for the autocorrelation inherent in the fMRI time series data using a non-parametric technique. Second, we use a generalized least squares approach to estimate 1) the within-subject variance component shared across the population, 2) the baseline FC strength, and 3) the FC's longitudinal trend. Our novel method for longitudinal FC networks seeks to account for the within-subject dependence across multiple visits, the variability due to the subjects being sampled from a population, and the autocorrelation present in fMRI time series data, while restricting the number of parameters in order to make the method computationally feasible and stable. We develop a permutation testing procedure to draw valid inference on group differences in the baseline FC network and change in FC over longitudinal time between a set of patients and a comparable set of controls. To examine performance, we run a series of simulations and apply the model to longitudinal fMRI data collected from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database. Overall, we found no difference in the global FC network between Alzheimer's disease patients and healthy controls, but did find differing local aging patterns in the FC between the left hippocampus and the posterior cingulate cortex. Copyright © 2018 Elsevier Inc. All rights reserved.

Longitudinal Care Improves Cessation in Smokers Who Do Not Initially Respond to Treatment by Increasing Cessation Self-Efficacy, Satisfaction, and Readiness to Quit: A Mediated Moderation Analysis.

PubMed

Burns, Rachel J; Rothman, Alexander J; Fu, Steven S; Lindgren, Bruce; Vock, David M; Joseph, Anne M

2016-02-01

The Tobacco Longitudinal Care study was a randomized controlled trial for smoking cessation. It demonstrated that longitudinal care for smoking cessation, in which telephone-based counseling and nicotine replacement therapy were offered for 12 months, was more effective than the standard 8-week treatment. This study aims to identify for whom and how longitudinal care increased the likelihood of abstinence. Mediated moderation analyses were utilized across three time points. There was a trend towards smokers who did not respond to treatment (i.e., were still smoking) by 21 days being more likely to be abstinent at 6 months if they received longitudinal care rather than usual care. Similarly, those who did not respond to treatment by 3 months were more likely to be abstinent at 12 months if they received longitudinal care. At both time points, the likelihood of abstinence did not differ across treatment conditions among participants who responded to treatment (i.e., quit smoking). The effect on 6-month outcomes was mediated by satisfaction and readiness to quit. Cessation self-efficacy, satisfaction, and readiness to quit mediated the effect on 12-month outcomes. The effect of treatment condition on the likelihood of abstinence at 18 months was not moderated by response to treatment at 6 months. Smokers who did not respond to initial treatment benefited from longitudinal care. Differential effects of treatment condition were not observed among those who responded to early treatment. Conditional assignment to longitudinal care may be useful. Determining for whom and how interventions work over time will advance theory and practice.