Priority of VHS Development Based in Potential Area using Principal Component Analysis

NASA Astrophysics Data System (ADS)

Meirawan, D.; Ana, A.; Saripudin, S.

2018-02-01

The current condition of VHS is still inadequate in quality, quantity and relevance. The purpose of this research is to analyse the development of VHS based on the development of regional potential by using principal component analysis (PCA) in Bandung, Indonesia. This study used descriptive qualitative data analysis using the principle of secondary data reduction component. The method used is Principal Component Analysis (PCA) analysis with Minitab Statistics Software tool. The results of this study indicate the value of the lowest requirement is a priority of the construction of development VHS with a program of majors in accordance with the development of regional potential. Based on the PCA score found that the main priority in the development of VHS in Bandung is in Saguling, which has the lowest PCA value of 416.92 in area 1, Cihampelas with the lowest PCA value in region 2 and Padalarang with the lowest PCA value.

Analysis of the characteristics and management of critical values in a newborn tertiary center in China.

PubMed

Wang, Zheng-Li; Du, Li-Zhong; Chen, Yi-Yu; Li, Lu-Quan; Lu, Qi; Liu, Ying; Cao, Lu-Ying; He, Yu; Yu, Jia-Lin

2017-02-01

Critical value reporting has been widely adopted by hospitals throughout the world, but there were few reports about neonatal critical values. This study aimed to analyze characteristics of the neonatal critical values considered at our center and to provide information on improving neonatal intensive care. A retrospective study of critical values at a newborn tertiary center in China was conducted to assess neonatal critical values according to test, distribution, reporting time, patient outcome and the impact to the therapy. In total, 926 critical values were recorded. Overall, 66.52% (616/926) of the items were reported within 24 hours of admission, 50.28% (465/926) during duty times and 54.75% (507/926) in the neonatal intensive care unit (NICU). The routine coagulation test was the most frequent source of critical values. Electrocardiography, blood gas analysis and therapeutic drug monitoring of drug levels were associated with the highest rates of treatment intervention (100%); routine coagulation tests were the lowest (23.14%). Sample quality was the main cause of false-positive critical values. The incidence of neonatal critical values peaked during the first 24 hours post-admission and during duty periods. Each newborn center needs to enact rapid treatment guidelines to address common critical values in order to facilitate clinical interventions. Periodically reviewing critical values could help to optimize clinical practices.

Attitudes toward neurosciences in medical students in Wuhan, China: a survey study.

PubMed

Lukas, Rimas V; Cooper, Brian; Morgan, Ivy; Brorson, James R; Dong, Hongmei; Sherer, Renslow

2014-01-01

Neurophobia is a well-described phenomenon among medical students in many countries. Little is reported concerning the perceptions of neurosciences among medical students in China. We surveyed senior medical students in Wuhan, China, on their perceptions of neuroscience. Students' self-assessments of knowledge in various specialties ranked neurology low, but not the lowest. Students' confidence in diagnosing neurological patients and managing neurological patients demonstrated significant correlation. A positive correlation was noted between confidence in these clinical parameters and the likelihood of specializing in neurology. Students reported bedside teaching and small group sessions as having the greatest value in learning neurology. The low, but not the lowest ranking of self-perceived knowledge in neurology by medical students in Wuhan, China, differs from findings reported in other countries. In this exploratory study the investigators hypothesize that the well-described phenomenon of neurophobia may exhibit a less pronounced influence in Wuhan, China. Copyright © 2014 Elsevier Inc. All rights reserved.

Novel measurement of spreading pattern of influenza epidemic by using weighted standard distance method: retrospective spatial statistical study of influenza, Japan, 1999–2009

PubMed Central

2012-01-01

Background Annual influenza epidemics occur worldwide resulting in considerable morbidity and mortality. Spreading pattern of influenza is not well understood because it is often hampered by the quality of surveillance data that limits the reliability of analysis. In Japan, influenza is reported on a weekly basis from 5,000 hospitals and clinics nationwide under the scheme of the National Infectious Disease Surveillance. The collected data are available to the public as weekly reports which were summarized into number of patient visits per hospital or clinic in each of the 47 prefectures. From this surveillance data, we analyzed the spatial spreading patterns of influenza epidemics using weekly weighted standard distance (WSD) from the 1999/2000 through 2008/2009 influenza seasons in Japan. WSD is a single numerical value representing the spatial compactness of influenza outbreak, which is small in case of clustered distribution and large in case of dispersed distribution. Results We demonstrated that the weekly WSD value or the measure of spatial compactness of the distribution of reported influenza cases, decreased to its lowest value before each epidemic peak in nine out of ten seasons analyzed. The duration between the lowest WSD week and the peak week of influenza cases ranged from minus one week to twenty weeks. The duration showed significant negative association with the proportion of influenza A/H3N2 cases in early phase of each outbreak (correlation coefficient was −0.75, P = 0.012) and significant positive association with the proportion of influenza B cases in the early phase (correlation coefficient was 0.64, P = 0.045), but positively correlated with the proportion of influenza A/H1N1 strain cases (statistically not significant). It is assumed that the lowest WSD values just before influenza peaks are due to local outbreak which results in small standard distance values. As influenza cases disperse nationwide and an epidemic reaches its peak, WSD value changed to be a progressively increasing. Conclusions The spatial distribution of nationwide influenza outbreak was measured by using a novel WSD method. We showed that spreading rate varied by type and subtypes of influenza virus using WSD as a spatial indicator. This study is the first to show a relationship between influenza epidemic trend by type/subtype and spatial distribution of influenza nationwide in Japan. PMID:22713508

Modeling and Optimization for Morphing Wing Concept Generation II. Part 1; Morphing Wing Modeling and Structural Sizing Techniques

NASA Technical Reports Server (NTRS)

Skillen, Michael D.; Crossley, William A.

2008-01-01

This report documents a series of investigations to develop an approach for structural sizing of various morphing wing concepts. For the purposes of this report, a morphing wing is one whose planform can make significant shape changes in flight - increasing wing area by 50% or more from the lowest possible area, changing sweep 30 or more, and / or increasing aspect ratio by as much as 200% from the lowest possible value. These significant changes in geometry mean that the underlying load-bearing structure changes geometry. While most finite element analysis packages provide some sort of structural optimization capability, these codes are not amenable to making significant changes in the stiffness matrix to reflect the large morphing wing planform changes. The investigations presented here use a finite element code capable of aeroelastic analysis in three different optimization approaches -a "simultaneous analysis" approach, a "sequential" approach, and an "aggregate" approach.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, James B.

We report the third in a series of ’exact’ quantum Monte Carlo calculations for the potential energy of the saddle point of the barrier for the reaction H + H{sub 2} → H{sub 2} + H. The barrier heights determined are 9.61 ± 0.01 in 1992/94, 9.608 ± 0.001 in 2003, and 9.6089 ± 0.0001 in 2016 (this work), all in kcal/mole and successively a factor of ten more accurate. The new value is below the lowest value from explicitly correlated Gaussian calculations and within the estimated limits of extrapolated multireference configuration calculations.

Response morphology and anatomy of tobacco (Nicotiana tabacum L.) plant on waterlogging

NASA Astrophysics Data System (ADS)

Nurhidayati, Tutik; Wardhani, Selfrina Puri; Purnobasuki, Hery; Hariyanto, Sucipto; Jadid, Nurul; Nurcahyani, Desy Dwi

2017-11-01

This study has conducted research on morphological and anatomical responses of some varieties of tobacco plants to waterlogging stress. Parameters measured were morphology, anatomy, and plants sensitivity index. Results were analyzed using two-way ANOVA followed by the Tukey test. The results show that waterlogging stress can reduce the growth of tobacco plants, including a decrease in plant height with the lowest value of 15.6 cm, root length reduction to the lowest value of 4.6 cm and plant dry weight reduction to the lowest value of 0.26 gr. But waterlogging stress can increase the number of adventitious roots with the highest value of 18.33. In addition, waterlogging stress can lead to the formation of aerenchyma tissue. The sensitivity index showed that plant varieties that are resistant to waterlogging stress are the varieties Kemloko 3 (index value of 0.03), varieties of Paiton 2 (index value of 0.18), and the varieties Kemloko 2 (index value of 0.42).

KEY COMPARISON Final report on APMP.EM-K6.a: APMP international comparison of ac-dc transfer standards at the lowest attainable level of uncertainty

NASA Astrophysics Data System (ADS)

Budovsky, Ilya

2010-01-01

The APMP international comparison of ac-dc transfer standards at the lowest attainable level of uncertainty, APMP.EM-K6a, started in 2000 and concluded in 2003. This comparison has offered the same range and frequencies as the key comparison CCEM-K6a with the view of providing the National Metrology Institutes (NMIs) of the APMP member economies with an opportunity to link the values of their standards for ac-dc transfer difference to the international reference values. The ac-dc difference of the travelling standard was measured with 3 V applied at standard frequencies of 1 kHz, 20 kHz, 100 kHz and 1 MHz, and optional frequencies of 50 kHz and 500 kHz. The travelling standard has not been damaged and has shown excellent stability. The results submitted by the overwhelming majority of the participants lie well within the reported uncertainty. At the standard frequencies the results have been linked to those of the CCEM-K6a key comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

The spectrum of singly ionized tungsten

NASA Astrophysics Data System (ADS)

Husain, Abid; Jabeen, S.; Wajid, Abdul

2018-05-01

The ab initio calculations were performed using Cowan's computer code for ground configuration5d46s incorporating other interacting even parity configurations 5d36s2 and 5d5, also for the three lowest excited configurations5d46p, 5d36s6p and 5d36s5f of odd parity matrix. The initial energy parameter scaling applied for Eav and ζ at 100% of the HFR values and Fk at 85%, Gk and Rk at 75% of the HFR values. The reported values of levels were taken from NIST ASD levels list. The levels were used to run least square fitted (LSF). This allowed adjusting the energy to the real values and hence a better prediction was achieved.

Accuracy of self-reported height, weight and waist circumference in a Japanese sample.

PubMed

Okamoto, N; Hosono, A; Shibata, K; Tsujimura, S; Oka, K; Fujita, H; Kamiya, M; Kondo, F; Wakabayashi, R; Yamada, T; Suzuki, S

2017-12-01

Inconsistent results have been found in prior studies investigating the accuracy of self-reported waist circumference, and no study has investigated the validity of self-reported waist circumference among Japanese individuals. This study used the diagnostic standard of metabolic syndrome to assess the accuracy of individual's self-reported height, weight and waist circumference in a Japanese sample. Study participants included 7,443 Japanese men and women aged 35-79 years. They participated in a cohort study's baseline survey between 2007 and 2011. Participants' height, weight and waist circumference were measured, and their body mass index was calculated. Self-reported values were collected through a questionnaire before the examination. Strong correlations between measured and self-reported values for height, weight and body mass index were detected. The correlation was lowest for waist circumference (men, 0.87; women, 0.73). Men significantly overestimated their waist circumference (mean difference, 0.8 cm), whereas women significantly underestimated theirs (mean difference, 5.1 cm). The sensitivity of self-reported waist circumference using the cut-off value of metabolic syndrome was 0.83 for men and 0.57 for women. Due to systematic and random errors, the accuracy of self-reported waist circumference was low. Therefore, waist circumference should be measured without relying on self-reported values, particularly in the case of women.

Iron monocyanide (FeCN): Spin-orbit and vibronic interactions in low-lying electronic states

NASA Astrophysics Data System (ADS)

Jerosimić, Stanka V.; Milovanović, Milan Z.

2018-04-01

The spin-orbit eigenvalues of low-energy quartet and sextet spatially degenerate electronic states of FeCN are reported, together with the combined effect of vibronic and spin-orbit interaction in the lowest-lying 14Δ and 16Δ states of FeCN, by using perturbational and variational method. Spin-orbit constants (ASO) have been calculated in the basis of: (a) two components of each degenerate state, (b) four components of 14Δ and 14Π (16Δ and 16Π) states, and (c) ten components of 16Δ, 16Π, 16Σ+, 14Δ, 14Π, and 14Σ+ states. The present calculations predict the values of ASO= -77 cm-1 for 16Δ and ASO= -108 cm-1 for 14Δ state in the lowest-energy spin-orbit manifolds of each state. The major perturbing state for the 14Δ state is the 14Π state (16Π for the sextet 16Δ). As expected, based on extremely small splitting and shallowness of the bending potential energy curves for the lowest-lying 4,6Δ states, the present study indicate that the vibronic coupling does not create significant splitting of the bending levels, but the influence of anharmonicity in the bending mode is more pronounced. However, the spin-orbit fine structure dominantly influences the spectra of this species.

Global trends in testicular cancer incidence and mortality.

PubMed

Rosen, Alexandre; Jayram, Gautam; Drazer, Michael; Eggener, Scott E

2011-08-01

Epidemiologic studies on testicular cancer have focused primarily on European countries. Global incidence and mortality have been less thoroughly evaluated. Our goal was to gain a better understanding of the most recent global age-standardized incidence and mortality rates for testicular cancer and to use these values to estimate a region's health care quality. Age-standardized incidence rate (ASIR) and age-standardized mortality rate (ASMR) for testicular cancer were obtained for men of all ages in 172 countries by using the GLOBOCAN 2008 database, reflecting the annual rate of cancer incidence and mortality per 100,000 men. These data were evaluated on a regional level to compare incidence and mortality rates. Global plots of these values were constructed to better visualize geographic distributions. Finally, the ratio of ASIR to ASMR was calculated as a method to assess each region's proficiency in diagnosing and effectively treating testicular cancer. ASIR and ASMR were analyzed by region, and each region's ratio of ASIR to ASMR was calculated. Testicular cancer ASIR is highest in Western Europe (7.8%), Northern Europe (6.7%), and Australia (6.5%). Asia and Africa had the lowest incidence (<1.0%). ASMR was highest in Central America (0.7%), western Asia (0.6%), and Central and Eastern Europe (0.6%). Mortality was lowest in North America, Northern Europe, and Australia (0.1-0.2%). The ASIR-ASMR ratio was highest in Australia (65.0%) and lowest in western Africa (1.0%). National reporting systems varied by country, and data quality may have fluctuated between regions. Testicular cancer incidence remains highest in developed nations with primarily Caucasian populations. Variable ASIR-ASMR ratios suggest markedly different geographic-specific reporting mechanisms, access to care, and treatment capabilities. Copyright © 2011 European Association of Urology. Published by Elsevier B.V. All rights reserved.

Enhanced spin-ordering temperature in ultrathin FeTe films grown on a topological insulator

NASA Astrophysics Data System (ADS)

Singh, Udai Raj; Warmuth, Jonas; Kamlapure, Anand; Cornils, Lasse; Bremholm, Martin; Hofmann, Philip; Wiebe, Jens; Wiesendanger, Roland

2018-04-01

We studied the temperature dependence of the diagonal double-stripe spin order in 1 and 2 unit cell thick layers of FeTe grown on the topological insulator B i2T e3 via spin-polarized scanning tunneling microscopy. The spin order persists up to temperatures which are higher than the transition temperature reported for bulk F e1 +yTe with lowest possible excess Fe content y . The enhanced spin order stability is assigned to a strongly decreased y with respect to the lowest values achievable in bulk crystal growth, and effects due to the interface between the FeTe and the topological insulator. The result is relevant for understanding the recent observation of a coexistence of superconducting correlations and spin order in this system.

76 FR 2313 - Atlantic Highly Migratory Species; Bluefin Tuna Bycatch Reduction in the Gulf of Mexico Pelagic...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-13

..., are the lowest observed values in the time series. The Commission may wish to protect the 2003 year... has implemented a series of management measures designed to regulate the incidental catch of BFT in... less well estimated, are the lowest observed values in the time series. The Commission may wish to...

Air Force KC-X Tanker Aircraft Program: Background and Issues for Congress

DTIC Science & Technology

2009-10-05

General ..................................................................................................................... 12 Best Value vs . Lowest...Druyan was a single “bad apple ” and that her actions did not negate the merits of leasing Boeing 767s for use as tankers. In February 2005, however...Force KC-X Tanker Aircraft Program: Background and Issues for Congress Congressional Research Service 17 Best Value vs . Lowest Cost The question of

HOMA-IR Values are Associated With Glycemic Control in Japanese Subjects Without Diabetes or Obesity: The KOBE Study.

PubMed

Hirata, Takumi; Higashiyama, Aya; Kubota, Yoshimi; Nishimura, Kunihiro; Sugiyama, Daisuke; Kadota, Aya; Nishida, Yoko; Imano, Hironori; Nishikawa, Tomofumi; Miyamatsu, Naomi; Miyamoto, Yoshihiro; Okamura, Tomonori

2015-01-01

Several studies have reported that insulin resistance was a major risk factor for the onset of type 2 diabetes mellitus in individuals without diabetes or obesity. We aimed to clarify the association between insulin resistance and glycemic control in Japanese subjects without diabetes or obesity. We conducted a community-based cross-sectional study including 1083 healthy subjects (323 men and 760 women) in an urban area. We performed multivariate regression analyses to estimate the association between the homeostasis model assessment of insulin resistance (HOMA-IR) values and markers of glycemic control, including glycated haemoglobin (HbA1c), 1,5-anhydroglucitol (1,5-AG), and fasting plasma glucose (FPG) levels, after adjustment for potential confounders. Compared with the lowest tertile of HOMA-IR values, the highest tertile was significantly associated with HbA1c and FPG levels after adjustment for potential confounders, both in men (HbA1c: β = 1.83, P = 0.001; FPG: β = 0.49, P < 0.001) and women (HbA1c: β = 0.82, P = 0.008; FPG: β = 0.39, P < 0.001). The highest tertile of HOMA-IR values was inversely associated with 1,5-AG levels compared with the lowest tertile (β = -18.42, P = 0.009) only in men. HOMA-IR values were associated with markers of glycemic control in Japanese subjects without diabetes or obesity. Insulin resistance may influence glycemic control even in a lean, non-diabetic Asian population.

Bimolecular reactions of carbenes: Proton transfer mechanism

NASA Astrophysics Data System (ADS)

Abu-Saleh, Abd Al-Aziz A.; Almatarneh, Mansour H.; Poirier, Raymond A.

2018-04-01

Here we report the bimolecular reaction of trifluoromethylhydroxycarbene conformers and the water-mediated mechanism of the 1,2-proton shift for the unimolecular trans-conformer by using quantum chemical calculations. The CCSD(T)/cc-pVTZ//MP2/cc-pVDZ potential-energy profile of the bimolecular reaction of cis- and trans-trifluoromethylhydroxycarbene, shows the lowest gas-phase barrier height of 13 kJ mol-1 compared to the recently reported value of 128 kJ mol-1 for the unimolecular reaction. We expect bimolecular reactions of carbene's stereoisomers will open a valuable field for new and useful synthetic strategies.

Reliability study of biometrics "do not contact" in myopia.

PubMed

Migliorini, R; Fratipietro, M; Comberiati, A M; Pattavina, L; Arrico, L

The aim of the study is a comparison between the actually achieved after surgery condition versus the expected refractive condition of the eye as calculated via a biometer. The study was conducted in a random group of 38 eyes of patients undergoing surgery by phacoemulsification. The mean absolute error was calculated between the predicted values from the measurements with the optical biometer and those obtained in the post-operative error which was at around 0.47% Our study shows results not far from those reported in the literature, and in relation, to the mean absolute error is among the lowest values at 0.47 ± 0.11 SEM.

Biological parameters in technogenic soils of a former sulphur mine

NASA Astrophysics Data System (ADS)

Siwik-Ziomek, Anetta; Brzezińska, Małgorzata; Lemanowicz, Joanna; Koper, Jan; Szarlip, Paweł

2018-04-01

This study was conducted on the soils originating from a reclamation area of the former sulphur mine in Tarnobrzeg, Poland. Soil was sampled 16 years after the completion of mining works with the open-pit method at Machów, as well as 7 years after sulphur mining via the `smelting' method in the Jeziórko mine was abandoned. Several biological parameters were examined: soil respiration, soil microbial biomass and the activity of rhodanese and arylsulphatase enzymes taking part in sulphur transformation within the site's soils. The soils showed a high total sulphur and sulphates content. The SO42- constituted a large fraction of total sulphur, in some cases, exceeding 80% or even 95% of total sulphur. The soil pH decreased due to the degrading effects of sulphur mining. In the soils studied from the locations with the lowest soil pH value, no activity of arylsulphatase was reported and the activity of rhodanese was lowest. The highest soil respiration values were recorded from the 0-5 cm layer in the areas covered with forest vegetation. A high soil respiration value at the waste heap at Machów wherein a very high concentration of Stot and SO42- was observed can be due to the ability of fungi to produce hyphal strands and to survive unfavourable conditions.

Measuring the Value of New Drugs: Validity and Reliability of 4 Value Assessment Frameworks in the Oncology Setting.

PubMed

Bentley, Tanya G K; Cohen, Joshua T; Elkin, Elena B; Huynh, Julie; Mukherjea, Arnab; Neville, Thanh H; Mei, Matthew; Copher, Ronda; Knoth, Russell; Popescu, Ioana; Lee, Jackie; Zambrano, Jenelle M; Broder, Michael S

2017-06-01

Several organizations have developed frameworks to systematically assess the value of new drugs. To evaluate the convergent validity and interrater reliability of 4 value frameworks to understand the extent to which these tools can facilitate value-based treatment decisions in oncology. Eight panelists used the American Society of Clinical Oncology (ASCO), European Society for Medical Oncology (ESMO), Institute for Clinical and Economic Review (ICER), and National Comprehensive Cancer Network (NCCN) frameworks to conduct value assessments of 15 drugs for advanced lung and breast cancers and castration-refractory prostate cancer. Panelists received instructions and published clinical data required to complete the assessments, assigning each drug a numeric or letter score. Kendall's Coefficient of Concordance for Ranks (Kendall's W) was used to measure convergent validity by cancer type among the 4 frameworks. Intraclass correlation coefficients (ICCs) were used to measure interrater reliability for each framework across cancers. Panelists were surveyed on their experiences. Kendall's W across all 4 frameworks for breast, lung, and prostate cancer drugs was 0.560 (P= 0.010), 0.562 (P = 0.010), and 0.920 (P < 0.001), respectively. Pairwise, Kendall's W for breast cancer drugs was highest for ESMO-ICER and ICER-NCCN (W = 0.950, P = 0.019 for both pairs) and lowest for ASCO-NCCN (W = 0.300, P = 0.748). For lung cancer drugs, W was highest pairwise for ESMO-ICER (W = 0.974, P = 0.007) and lowest for ASCO-NCCN (W = 0.218, P = 0.839); for prostate cancer drugs, pairwise W was highest for ICER-NCCN (W = 1.000, P < 0.001) and lowest for ESMO-ICER and ESMO-NCCN (W = 0.900, P = 0.052 for both pairs). When ranking drugs on distinct framework subdomains, Kendall's W among breast cancer drugs was highest for certainty (ICER, NCCN: W = 0.908, P = 0.046) and lowest for clinical benefit (ASCO, ESMO, NCCN: W = 0.345, P = 0.436). Among lung cancer drugs, W was highest for toxicity (ASCO, ESMO, NCCN: W = 0. 944, P < 0.001) and lowest for certainty (ICER, NCCN: W = 0.230, P = 0.827); and among prostate cancer drugs, it was highest for quality of life (ASCO, ESMO: W = 0.986, P = 0.003) and lowest for toxicity (ASCO, ESMO, NCCN: W = 0.200, P = 0.711). ICC (95% CI) for ASCO, ESMO, ICER, and NCCN were 0.800 (0.660-0.913), 0.818 (0.686-0.921), 0.652 (0.466-0.834), and 0.153 (0.045-0.371), respectively. When scores were rescaled to 0-100, NCCN provided the narrowest band of scores. When asked about their experiences using the ASCO, ESMO, ICER, and NCCN frameworks, panelists generally agreed that the frameworks were logically organized and reasonably easy to use, with NCCN rated somewhat easier. Convergent validity among the ASCO, ESMO, ICER, and NCCN frameworks was fair to excellent, increasing with clinical benefit subdomain concordance and simplicity of drug trial data. Interrater reliability, highest for ASCO and ESMO, improved with clarity of instructions and specificity of score definitions. Continued use, analyses, and refinements of these frameworks will bring us closer to the ultimate goal of using value-based treatment decisions to improve patient care and outcomes. This work was funded by Eisai Inc. Copher and Knoth are employees of Eisai Inc. Bentley, Lee, Zambrano, and Broder are employees of Partnership for Health Analytic Research, a health services research company paid by Eisai Inc. to conduct this research. For this study, Cohen, Huynh, and Neville report fees from Partnership for Health Analytic Research. Outside of this study, Cohen receives grants and direct consulting fees from various companies that manufacture and market pharmaceuticals. Mei reports a grant from Eisai Inc. during this study. The other authors have no disclosures to report. Study concept and design were contributed by Bentley and Broder, with assistance from Elkin and Cohen. Bentley took the lead in data collection, along with Elkin, Huynh, Mukherjea, Neville, Mei, Popescu, Lee, and Zambrano. Data interpretation was performed by Bentley and Broder, along with Elkin, Cohen, Copher, and Knoth. The manuscript was written primarily by Bentley, along with Elkin and Broder, and revised by Bentley, Broder, Elkin, Cohen, Copher, and Knoth. Select components of this work's methods were presented at ISPOR 19th Annual European Congress held in Vienna, Austria, October 29-November 2, 2016, and Society for Medical Decision Making 38th Annual North American Meeting held in Vancouver, Canada, October 23-26, 2016.

Contract Source Selection: An Analysis of Lowest Price Technically Acceptable and Tradeoff Strategies

DTIC Science & Technology

2016-06-01

thorough market research, acquisition professionals must decide at an early stage which source selection strategy (lowest price technically...minimizing risk and ensuring best value for all stakeholders. On the basis of thorough market research, acquisition professionals must decide at an early...price-based, market -driven environment from requirements development through properly disposal. Source selection must be 8 made on a ‘best value

Thermochemical properties for isooctane and carbon radicals: computational study.

PubMed

Snitsiriwat, Suarwee; Bozzelli, Joseph W

2013-01-17

Thermochemical properties for isooctane, its internal rotation conformers, and radicals with corresponding bond energies are determined by use of computational chemistry. Enthalpies of formation are determined using isodesmic reactions with B3LYP density function theory and composite CBS-QB3 methods. Application of group additivity with comparison to calculated values is illustrated. Entropy and heat capacities are determined using geometric parameters, internal rotor potentials, and frequencies from B3LYP/6-31G(d,p) calculations for the lowest energy conformer. Internal rotor potentials are determined for the isooctane parent and for the primary, secondary, and tertiary radicals in order to identify isomer energies. Intramolecular interactions are shown to have a significant effect on the enthalpy of formation of the isooctane parent and its radicals. The computed standard enthalpy of formation for the lowest energy conformers of isooctane from this study is -54.40 ± 1.60 kcal mol(-1), which is 0.8 kcal mol(-1) lower than the evaluated experimental value -53.54 ± 0.36 kcal mol(-1). The standard enthalpy of formation for the primary radical for a methyl on the quaternary carbon is -5.00 ± 1.69 kcal mol(-1), for the primary radical on the tertiary carbon is -5.18 ± 1.69 kcal mol(-1), for the secondary isooctane radical is -9.03 ± 1.84 kcal mol(-1), and for the tertiary isooctane radical is -12.30 ± 2.02 kcal mol(-1). Bond energy values for the isooctane radicals are 100.64 ± 1.73, 100.46 ± 1.73, 96.41 ± 1.88 and 93.14 ± 2.05 kcal mol(-1) for C3•CCCC2, C3CCCC2•, C3CC•CC2, and C3CCC•C2, respectively. Entropy and heat capacity values are reported for the lowest energy homologues.

Residual zonal flows in tokamaks and stellarators at arbitrary wavelengths

NASA Astrophysics Data System (ADS)

Monreal, Pedro; Calvo, Iván; Sánchez, Edilberto; Parra, Félix I.; Bustos, Andrés; Könies, Axel; Kleiber, Ralf; Görler, Tobias

2016-04-01

In the linear collisionless limit, a zonal potential perturbation in a toroidal plasma relaxes, in general, to a non-zero residual value. Expressions for the residual value in tokamak and stellarator geometries, and for arbitrary wavelengths, are derived. These expressions involve averages over the lowest order particle trajectories, that typically cannot be evaluated analytically. In this work, an efficient numerical method for the evaluation of such expressions is reported. It is shown that this method is faster than direct gyrokinetic simulations performed with the Gene and EUTERPE codes. Calculations of the residual value in stellarators are provided for much shorter wavelengths than previously available in the literature. Electrons must be treated kinetically in stellarators because, unlike in tokamaks, kinetic electrons modify the residual value even at long wavelengths. This effect, that had already been predicted theoretically, is confirmed by gyrokinetic simulations.

LPTA Versus Tradeoff: Analysis of Contract Source Selection Strategies and Performance Outcomes

DTIC Science & Technology

2016-06-01

methodologies contracting professionals employ to acquire what the DOD needs. Contracting professionals may use lowest price technically acceptable (LPTA) and...contract management process, source selection, lowest price technically acceptable, tradeoff 15. NUMBER OF PAGES 69 16. PRICE CODE 17. SECURITY...use lowest price technically acceptable (LPTA) and tradeoff strategies to procure requirements to maximize the overall best value to the government

OSD’s Obligation & Expenditure Rate Goals: An Examination of the Factors Contributing to the Interference

DTIC Science & Technology

2015-04-30

Proposal Prep Delays [F6]). For this particular factor, PCOs reported the highest impact while PMs ranked it as the lowest. Senior staff cited that Shortage...of Contracting Officers (F4) created the highest impact, while PCOs reported it had the lowest impact. With a 7% , it was the lowest among all six

Assessing values for health: numeracy matters.

PubMed

Woloshin, S; Schwartz, L M; Moncur, M; Gabriel, S; Tosteson, A N

2001-01-01

Patients' values are fundamental to decision models, cost-effectiveness analyses, and pharmacoeconomic analyses. The standard methods used to assess how patients value different health states are inherently quantitative. People without strong quantitative skills (i.e., low numeracy) may not be able to complete these tasks in a meaningful way. To determine whether the validity of utility assessments depends on the respondent's level of numeracy, the authors conducted in-person interviews and written surveys and assessed utility for the current health for 96 women volunteers. Numeracy was measured using a previously validated 3-item scale. The authors examined the correlation between self-reported health and utility for current health (assessed using the standard gamble, time trade-off, and visual analog techniques) across levels of numeracy. For half of the women, the authors also assessed standard gamble utility for 3 imagined health states (breast cancer, heart disease, and osteoporosis) and asked how much the women feared each disease. Respondent ages ranged from 50 to 79 years (mean = 63), all were high school graduates, and 52% had a college or postgraduate degree. Twenty-six percent answered 0 or only 1 of the numeracy questions correctly, 37% answered 2 correctly, and 37% answered all 3 correctly. Among women with the lowest level of numeracy, the correlation between utility for current health and self-reported health was in the wrong direction (i.e., worse health valued higher than better health): for standard gamble, Spearman r=-0.16, P = 0.44;for time trade-off, Spearman r=-0.13, P=0.54. Among the most numerate women, the authors observed a fair to moderate positive correlation with both standard gamble (Spearman r=0.22, P=0.19) and time trade-off (Spearman r=0.50, P=0.002). In contrast, using the visual analog scale, the authors observed a substantial correlation in the expected direction at all levels of numeracy (Spearman r= 0.82, 0.50, and 0.60 for women answering 0-1, 2, and 3 numeracy questions, respectively; all Ps < or = 0.003). With regard to the imagined health states, the most feared disease had the lowest utility for 35% of the women with the lowest numeracy compared to 76% of the women with the highest numeracy (P=0.03). The validity of standard utility assessments is related to the subject's facility with numbers. Limited numeracy may be an important barrier to meaningfully assessing patients' values using the standard gamble and time trade-off techniques.

Biological and Physical Conditions at a Newly Placed Gravel Bar Habitat in the Tombigbee River.

DTIC Science & Technology

1988-03-01

much lower than values reported for other lotic systems. The lowest biomass estimate in Table 7 (1.395 g AFDW/m2 for the Pine River, Mich.) is over twice...that were close to dense macroinvertebrate communities. The habitat at Columbus is unique because the riffles were constructed from barren substrates...AFDW/m Reference Pine River, Mich. Barber and Kevern natural, trout stream, 61.625 1.395 1973 Jun-Oct Mink Creek, Idaho 6.907* 10.811 Minshall 1981

Improved Potency of Indole-Based NorA Efflux Pump Inhibitors: From Serendipity toward Rational Design and Development.

PubMed

Buonerba, Federica; Lepri, Susan; Goracci, Laura; Schindler, Bryan D; Seo, Susan M; Kaatz, Glenn W; Cruciani, Gabriele

2017-01-12

The NorA efflux pump is a potential drug target for reversal of resistance to selected antibacterial agents, and recently we described indole-based inhibitor candidates. Herein we report a second class of inhibitors derived from them but with significant differences in shape and size. In particular, compounds 13 and 14 are very potent inhibitors in that they demonstrated the lowest IC 50 values (2 μM) ever observed among all indole-based compounds we have evaluated.

Heat and Moisture Transport in the Atmospheric Boundary Layer.

DTIC Science & Technology

1987-01-05

first part of the report is a review of recent work on the analytical treatment air flow over low hills, in which a framework has been established...concentration q, and also the nature of the vegetation. The lowest value of this ratio is zero, when the winds are moderate, the air if dry and all the energy is...increases the heat flux from the ground. (ii) In conditions where there is a strong, dry air flow over irrigated vegetation, ri >> ra, ri >> rst, then13

HOMA-IR Values are Associated With Glycemic Control in Japanese Subjects Without Diabetes or Obesity: The KOBE Study

PubMed Central

Hirata, Takumi; Higashiyama, Aya; Kubota, Yoshimi; Nishimura, Kunihiro; Sugiyama, Daisuke; Kadota, Aya; Nishida, Yoko; Imano, Hironori; Nishikawa, Tomofumi; Miyamatsu, Naomi; Miyamoto, Yoshihiro; Okamura, Tomonori

2015-01-01

Background Several studies have reported that insulin resistance was a major risk factor for the onset of type 2 diabetes mellitus in individuals without diabetes or obesity. We aimed to clarify the association between insulin resistance and glycemic control in Japanese subjects without diabetes or obesity. Methods We conducted a community-based cross-sectional study including 1083 healthy subjects (323 men and 760 women) in an urban area. We performed multivariate regression analyses to estimate the association between the homeostasis model assessment of insulin resistance (HOMA-IR) values and markers of glycemic control, including glycated haemoglobin (HbA1c), 1,5-anhydroglucitol (1,5-AG), and fasting plasma glucose (FPG) levels, after adjustment for potential confounders. Results Compared with the lowest tertile of HOMA-IR values, the highest tertile was significantly associated with HbA1c and FPG levels after adjustment for potential confounders, both in men (HbA1c: β = 1.83, P = 0.001; FPG: β = 0.49, P < 0.001) and women (HbA1c: β = 0.82, P = 0.008; FPG: β = 0.39, P < 0.001). The highest tertile of HOMA-IR values was inversely associated with 1,5-AG levels compared with the lowest tertile (β = −18.42, P = 0.009) only in men. Conclusions HOMA-IR values were associated with markers of glycemic control in Japanese subjects without diabetes or obesity. Insulin resistance may influence glycemic control even in a lean, non-diabetic Asian population. PMID:26005064

Regression Equations for Monthly and Annual Mean and Selected Percentile Streamflows for Ungaged Rivers in Maine

USGS Publications Warehouse

Dudley, Robert W.

2015-12-03

The largest average errors of prediction are associated with regression equations for the lowest streamflows derived for months during which the lowest streamflows of the year occur (such as the 5 and 1 monthly percentiles for August and September). The regression equations have been derived on the basis of streamflow and basin characteristics data for unregulated, rural drainage basins without substantial streamflow or drainage modifications (for example, diversions and (or) regulation by dams or reservoirs, tile drainage, irrigation, channelization, and impervious paved surfaces), therefore using the equations for regulated or urbanized basins with substantial streamflow or drainage modifications will yield results of unknown error. Input basin characteristics derived using techniques or datasets other than those documented in this report or using values outside the ranges used to develop these regression equations also will yield results of unknown error.

Comparison of different final impression techniques for management of resorbed mandibular ridge: a case report.

PubMed

Yadav, Bhupender; Jayna, Manisha; Yadav, Harish; Suri, Shrey; Phogat, Shefali; Madan, Reshu

2014-01-01

The history of complete denture impression procedures has been influenced largely by the development of impression materials from which new techniques and ideas arose. The purpose of this study was to compare the retention of complete dentures made by using different impression techniques like conventional, admixed, all green, and functional techniques. The results showed that there was significant difference in retention between the six techniques where functional technique showed the highest mean value of retention followed by elastomeric, all green, and admixed, while cocktail and green stick compound showed the lowest mean value. However, on clinical examination, the retention produced by the six techniques was satisfactory.

Comparison of Different Final Impression Techniques for Management of Resorbed Mandibular Ridge: A Case Report

PubMed Central

Yadav, Bhupender; Jayna, Manisha; Yadav, Harish; Suri, Shrey; Phogat, Shefali; Madan, Reshu

2014-01-01

The history of complete denture impression procedures has been influenced largely by the development of impression materials from which new techniques and ideas arose. The purpose of this study was to compare the retention of complete dentures made by using different impression techniques like conventional, admixed, all green, and functional techniques. The results showed that there was significant difference in retention between the six techniques where functional technique showed the highest mean value of retention followed by elastomeric, all green, and admixed, while cocktail and green stick compound showed the lowest mean value. However, on clinical examination, the retention produced by the six techniques was satisfactory. PMID:25180105

Quality ratings of frequency-compressed speech by participants with extensive high-frequency dead regions in the cochlea

PubMed Central

Salorio-Corbetto, Marina; Baer, Thomas; Moore, Brian C. J.

2017-01-01

Abstract Objective: The objective was to assess the degradation of speech sound quality produced by frequency compression for listeners with extensive high-frequency dead regions (DRs). Design: Quality ratings were obtained using values of the starting frequency (Sf) of the frequency compression both below and above the estimated edge frequency, fe, of each DR. Thus, the value of Sf often fell below the lowest value currently used in clinical practice. Several compression ratios were used for each value of Sf. Stimuli were sentences processed via a prototype hearing aid based on Phonak Exélia Art P. Study sample: Five participants (eight ears) with extensive high-frequency DRs were tested. Results: Reductions of sound-quality produced by frequency compression were small to moderate. Ratings decreased significantly with decreasing Sf and increasing CR. The mean ratings were lowest for the lowest Sf and highest CR. Ratings varied across participants, with one participant rating frequency compression lower than no frequency compression even when Sf was above fe. Conclusions: Frequency compression degraded sound quality somewhat for this small group of participants with extensive high-frequency DRs. The degradation was greater for lower values of Sf relative to fe, and for greater values of CR. Results varied across participants. PMID:27724057

Low-loss lateral-extensional piezoelectric filters on ultrananocrystalline diamond.

PubMed

Fatemi, Hediyeh; Abdolvand, Reza

2013-09-01

In this work, lateral-extensional thin-film piezoelectric- on-diamond (TPoD) filters with very low insertion loss (IL) values (<4 dB) are reported. Two different lateral-extensional modes of a resonant structure are coupled together to realize a two-pole filter. The filters of this work exhibit low IL values, with fractional bandwidth between 0.08% and 0.2%, and have a very small footprint. This paper reports on the lowest IL in the literature for lateral-extensional thin-film piezoelectric filters with 50 Ω terminations in the GSM frequency band (~900 MHz). The narrow-band filters of this work are fabricated on three ultrananocrystalline diamond substrates to achieve higher frequencies without excessive reduction in the feature size. The paper also thoroughly studies the parameters that affect the performance of such filters and then discussions are evaluated by the statistical data collected from the fabricated wafers.

Monitoring the clean-up operation of agricultural fields flooded with red mud in Hungary.

PubMed

Uzinger, Nikolett; Rékási, Márk; Anton, Áron D; Koós, Sándor; László, Péter; Anton, Attila

2016-12-01

In the course of the clean-up operation after the red mud inundation in 2010, red mud was removed from the soil surface in places where the layer was more than 5 cm deep. Before its removal, the red mud seeped into the soil. In 2012, soil samples were taken from depths of 0 to 20 and 20 to 40 cm on some of the affected areas. The parameters investigated were pH, organic matter, salt%, and the total and mobile fractions of various elements. The values recorded in 2012 were compared with those measured immediately after the removal of the red mud in 2010 and with the background and clean-up target concentrations. The pH values remained below the designated limit, while the salt content only exhibited values in the weakly salty range on areas at the greatest distance from the dam. In the central part of the inundated area, total Na contents above the 900 mg/kg target value were observed, but the Na content in the 0-20-cm layer generally exhibited a decrease due to leaching. The pH and As concentration also showed a decline on several areas compared with the values recorded in 2010. Total As and Co contents in excess of the target values were recorded on the lowest-lying part of the flooded area, probably because the finest red mud particles were deposited the furthest from the dam, where they seeped into the soil. Nevertheless, the mobility and plant availability of both elements remained moderate. The total contents of both Co and Mo, however, exhibited a significant rise compared with both the background value and the 2010 data. The monitoring of the cleaned-up areas showed that after a 2-year period element concentrations that exceeded the target values and could be attributed to the red mud pollution were only detectable on the lowest-lying areas.

Risk Analysis of Coastal Disaster of Semarang City, Indonesia

NASA Astrophysics Data System (ADS)

Sunaryo; Ambariyanto; Sugianto, Denny Nugroho; Helmi, Muhammad; Kaimuddin, Awaluddin Halirin; Indarjo, Agus

2018-02-01

Coastal areas are highly vulnerable to disasters, as they are affected by events occurring both on land and at sea. In the development of cities in these areas, information on vulnerability levels is needed as a consideration in determining policy. This study aims to identify potential vulnerability of Semarang city, and to investigate the potential of hazard and disaster risk levels of the city. The study was conducted in 17 villages in the northern coastal area of Semarang. The assessment approach used was score analysis to some variables, i.e geomorphology, erosion, coastal slope, waves and socio-economic aspects. The research showed that the highest level of coastal vulnerability in the Semarang city were at three villages i.e.Terboyo Kulon, Terboyo Wetan and Trimulyo with value of 4.5; while the lowest level were at the Maron beach, Marina beach and Tanah Mas with value of 2.8. The highest potential coastal hazard in the Semarang city were at two villages i.e. Tanjung Mas and Tambak Lorok with value of 4.5; and the lowest value were in the village of Randugarut, Karanganyar, Tugurejo, Marina beach and Tanah Mas with value of 1.25.The highest level of coastal risk in the Semarang city were in the Trimulyo village with value of 3.13; and the lowest level were in the Marina beach and Tanah mas with value of 1.32.

Corrosion of carbon steels, stainless steels, and titanium in aqueous lithium bromide solution

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guinon, J.L.; Garcia-Anton, J.; Perez-Herranz, V.

1994-03-01

Effects of lithium bromide (LiBr) concentration, pH, temperature, exposure time, and the action of some inhibitors on corrosion of several carbon (C) steels, stainless steels (SS), and a titanium (Ti) alloy were studied. Corrosion rates were determined by the polarization resistance method and compared to rates determined by weight-loss measurements. Pitting potentials (E[sub p]) were evaluated in neutral LiBr solution and with different inhibitors. Pit density and average pit depth depended on the metal tested, with lowest values for Ti, the next lowest values for type 316 SS (UNS S31600), and the highest values for UNS G41350 tempered steel.

The Development and Implementation of Career Information and Guidance Systems to Enhance Recruitment and Retention of ROTC Cadets for Army Careers

DTIC Science & Technology

1990-07-01

relations, variety, working conditions, cultural identity, physical prowess, and economic security. The measures of reliability were computed for the VS: 1...Prowess, Ability Utilization, and Physical Activity and the lowest scale scores on Cultural Identity, Social Relations, and Prestige. Those with neutral...and Cultural Identity and the lowest scale scores on Physical Prowess, Advancement, and Risk. Table 14 Highest and Lowest Rated Value Scale Dimensions

Oxidative stability and lipid oxidation flavoring volatiles in antioxidants treated chicken meat patties during storage.

PubMed

Sohaib, Muhammad; Anjum, Faqir Muhammad; Arshad, Muhammad Sajid; Imran, Muhammad; Imran, Ali; Hussain, Shahzad

2017-02-01

Chicken meat contains higher percentage of polyunsaturated fatty acids that are susceptible to oxidative deterioration ultimately leading towards lower consumer acceptability for chicken meat products. Accordingly, meat processing industries are looking for combinations of natural antioxidants to enhance the oxidative stability and consumer acceptability of meat based products. The present study aimed to investigate the influence of directly added quercetin dihydrate in combination with α-tocopherol on oxidative stability, color characteristics, total carbonyls and flavor volatile compounds in chicken meat patties. Considering the preliminary studies, 3 levels of quercetin dihdrate @ 25, 50 and 100 mg/kg meat in combination with α-tocopherol at the rate 100 and 200 mg/kg meat were added to develop chicken meat patties and were stored at refrigeration temperature for 7 days. The oxidative stability of the antioxidant treated patties was determined by measuring malonaldehydes using TBARS and total carbonyls assay. The color (Lightness, redness and yellowness) of the patties was determined by using Konica Minolta Color Meter. Moreover, the volatile compounds were measured through gas chromatography at various storage intervals. The results elucidated that quercetin dehydrate inclusion at the rate of 50 mg/kg meat as well as particularly 100 mg/kg meat decreased the oxidation by reducing generation of malonaldehydes and total carbonyls in treated patties. Highest value for TBARS at initiation of storage was reported in (T 0 ) as 1.93 ± 0.02 whereas lowest were reported in T 6 and T 5 as 0.37 ± 0.01 and 0.38 ± 0.03 that were increased to 3.47 ± 0.14, 0.90 ± 0.05 and 0.94 ± 0.34 at the completion of storage. Moreover, the lowest carbonyls also reported in T6 and the values at various storage intervals (1st, 3rd and 7th) were as 0.59 ± 0.025, 0.77 ± 0.015 and 1.02 ± 0.031, respectively. The antioxidants inclusion also inhibited volatile flavoring compounds particularly aldehydes like hexanal and pentanal in a dose dependent manner (p ≤ 0.05). Lowest hexanal values reported in T 6 as 2488 ± 103 followed by T 4 (3701 ± 111) at the start of the trial whereas highest in T 0 (control) as 54,768 ± 431 that were increased to 9569 ± 607, 112,550 ± 897 and 359,826 ± 1285, correspondingly. The hexanal, as a critical indicator for the determination of volatiles in meat based products, was decreased with the addition of antioxidants and its highest values were reported in control group. Quercetin dihydrate addition along with alpha tocopherol is a pragmatic choice to improve oxidative storability and volatile flavor compounds in cooked meat patties. The data obtained will help meat processor to better develop antioxidant enriched formulations to augment oxidative stability and quality of processed meat products.

Stable Isotopes of Precipitation During Tropical Sumatra Squalls in Singapore

NASA Astrophysics Data System (ADS)

He, Shaoneng; Goodkin, Nathalie F.; Kurita, Naoyuki; Wang, Xianfeng; Rubin, Charles Martin

2018-04-01

Sumatra Squalls, organized bands of thunderstorms, are the dominant mesoscale convective systems during the intermonsoon and southwest monsoon seasons in Singapore. To understand how they affect precipitation isotopes, we monitored the δ value of precipitation daily and continuously (every second and integrated over 30 s) during all squalls in 2015. We found that precipitation δ18O values mainly exhibit a "V"-shape pattern and less commonly a "W"-shape pattern. Variation in δ18O values during a single event is about 1 to 6‰ with the lowest values mostly observed in the stratiform zone, which agrees with previous observations and modeling simulations. Reevaporation can significantly affect δ values, especially in the last stage of the stratiform zone. Daily precipitation is characterized by periodic negative shifts in δ value, largely associated with the squalls rather than moisture source change. The shifts can be more than 10‰, larger than intraevent variation. Initial δ18O values of events are highly variable, and those with the lowest values also have the lowest initial values. Therefore, past convective activities in the upwind area can significantly affect the δ18O, and convection at the sampling site has limited contribution to isotopic variability. A significant correlation between precipitation δ18O value and regional outgoing longwave radiation and rainfall in the Asian monsoon region and western Pacific suggests that regional organized convection probably drives stable isotopic compositions of precipitation. A drop in the frequency of the squalls in 2015 is related to weak organized convection in the region caused by El Niño.

Evaluation of the pepsin digestibility assay for predicting amino acid digestibility of meat and bone meals.

PubMed

Davis, T M; Parsons, C M; Utterback, P L; Kirstein, D

2015-05-01

Sixteen meat and bone meal (MBM) samples were obtained and selected from various company plants to provide a wide range in pepsin nitrogen digestibility values. Pepsin digestibility was determined using either 0.02 or 0.002% pepsin. Amino acid (AA) digestibility of the 16 MBM samples was then determined using a precision-fed cecectomized rooster assay. The 0.02% pepsin digestibility values were numerically higher than the 0.002% pepsin values. The values varied from 77 to 93% for 0.02% pepsin and from 67 to 91% for 0.002% pepsin. The rooster AA digestibility results showed a wide range of values among MBM samples mostly due to the 4 samples having lowest and highest AA digestibility. A precision-fed broiler chick ileal AA digestibility assay confirmed that there were large differences in AA digestibility among the MBM samples having the lowest and highest rooster digestibility values. Correlation analyses between pepsin and AA digestibility values showed that the correlation values (r) were highly significant (P < 0.0001) for all AA when all 16 MBM samples were included in the analysis. However, when the MBM samples with the 2 lowest and the 2 highest rooster digestibility values were not included in the correlation analyses, the correlation coefficient values (r) were generally very low and not significant (P > 0.05). The results indicated that the pepsin nitrogen digestibility assay is only useful for detecting large differences in AA digestibility among MBM. There also was no advantage for using 0.02 versus 0.002% pepsin. © 2015 Poultry Science Association Inc.

A measurement of the proton structure function F2( x, Q2) at low x and low Q2 at HERA

NASA Astrophysics Data System (ADS)

Adloff, C.; Aid, S.; Anderson, M.; Andreev, V.; Andrieu, B.; Arkadov, V.; Arndt, C.; Ayyaz, I.; Babaev, A.; Bähr, J.; Bán, J.; Ban, Y.; Baranov, P.; Barrelet, E.; Barschke, R.; Bartel, W.; Bassler, U.; Beck, H. P.; Beck, M.; Behrend, H.-J.; Belousov, A.; Berger, Ch.; Bernardi, G.; Bertrand-Coremans, G.; Beyer, R.; Biddulph, P.; Bispham, P.; Bizot, J. C.; Borras, K.; Botterweck, F.; Boudry, V.; Bourov, S.; Braemer, A.; Braunschweig, W.; Brisson, V.; Brückner, W.; Bruel, P.; Bruncko, D.; Brune, C.; Buchholz, R.; Büngener, L.; Bürger, J.; Büsser, F. W.; Buniatian, A.; Burke, S.; Burton, M. J.; Buschhorn, G.; Calvet, D.; Campbell, A. J.; Carli, T.; Charlet, M.; Clarke, D.; Clerbaux, B.; Cocks, S.; Contreras, J. G.; Cormack, C.; Coughlan, J. A.; Courau, A.; Cousinou, M.-C.; Cox, B. E.; Cozzika, G.; Cussans, D. G.; Cvach, J.; Dagoret, S.; Dainton, J. B.; Dau, W. D.; Daum, K.; David, M.; Davis, C. L.; De Roeck, A.; De Wolf, E. A.; Delcourt, B.; Dirkmann, M.; Dixon, P.; Dlugosz, W.; Dollfus, C.; Donovan, K. T.; Dowell, J. D.; Dreis, H. B.; Droutskoi, A.; Ebert, J.; Ebert, T. R.; Eckerlin, G.; Efremenko, V.; Egli, S.; Eichler, R.; Eisele, F.; Eisenhandler, E.; Elsen, E.; Erdmann, M.; Fahr, A. B.; Favart, L.; Fedotov, A.; Felst, R.; Feltesse, J.; Ferencei, J.; Ferrarotto, F.; Flamm, K.; Fleischer, M.; Flieser, M.; Flügge, G.; Fomenko, A.; Formánek, J.; Foster, J. M.; Franke, G.; Gabathuler, E.; Gabathuler, K.; Gaede, F.; Garvey, J.; Gayler, J.; Gebauer, M.; Genzel, H.; Gerhards, R.; Glazov, A.; Goerlich, L.; Gogitidze, N.; Goldberg, M.; Goldner, D.; Golec-Biernat, K.; Gonzalez-Pineiro, B.; Gorelov, I.; Grab, C.; Grässler, H.; Greenshaw, T.; Griffiths, R. K.; Grindhammer, G.; Gruber, A.; Gruber, C.; Hadig, T.; Haidt, D.; Hajduk, L.; Haller, T.; Hampel, M.; Haynes, W. J.; Heinemann, B.; Heinzelmann, G.; Henderson, R. C. W.; Henschel, H.; Herynek, I.; Hess, M. F.; Hewitt, K.; Hiller, K. H.; Hilton, C. D.; Hladký, J.; Höppner, M.; Hoffmann, D.; Holtom, T.; Horisberger, R.; Hudgson, V. L.; Hütte, M.; Ibbotson, M.; İşsever, Ç.; Itterbeck, H.; Jacholkowska, A.; Jacobsson, C.; Jacquet, M.; Jaffre, M.; Janoth, J.; Jansen, D. M.; Jönsson, L.; Johnson, D. P.; Jung, H.; Kalmus, P. I. P.; Kander, M.; Kant, D.; Kathage, U.; Katzy, J.; Kaufmann, H. H.; Kaufmann, O.; Kausch, M.; Kazarian, S.; Kenyon, I. R.; Kermiche, S.; Keuker, C.; Kiesling, C.; Klein, M.; Kleinwort, C.; Knies, G.; Köhler, T.; Köhne, J. H.; Kolanoski, H.; Kolya, S. D.; Korbel, V.; Kostka, P.; Kotelnikov, S. K.; Krämerkämper, T.; Krasny, M. W.; Krehbiel, H.; Krücker, D.; Küpper, A.; Küster, H.; Kuhlen, M.; Kurča, T.; Kurzhöfer, J.; Laforge, B.; Landon, M. P. J.; Lange, W.; Langenegger, U.; Lebedev, A.; Lehner, F.; Lemaitre, V.; Levonian, S.; Lindstroem, M.; Linsel, F.; Lipinski, J.; List, B.; Lobo, G.; Lomas, J. W.; Lopez, G. C.; Lubimov, V.; Lüke, D.; Lytkin, L.; Magnussen, N.; Mahlke-Krüger, H.; Malinovski, E.; Maraček, R.; Marage, P.; Marks, J.; Marshall, R.; Martens, J.; Martin, G.; Martin, R.; Martyn, H.-U.; Martyniak, J.; Mavroidis, T.; Maxfield, S. J.; McMahon, S. J.; Mehta, A.; Meier, K.; Merkel, P.; Metlica, F.; Meyer, A.; Meyer, A.; Meyer, H.; Meyer, J.; Meyer, P.-O.; Migliori, A.; Mikocki, S.; Milstead, D.; Moeck, J.; Moreau, F.; Morris, J. V.; Mroczko, E.; Müller, D.; Walter, T.; Müller, K.; Murín, P.; Nagovizin, V.; Nahnhauer, R.; Naroska, B.; Naumann, Th.; Négri, I.; Newman, P. R.; Newton, D.; Nguyen, H. K.; Nicholls, T. C.; Niebergall, F.; Niebuhr, C.; Niedzballa, Ch.; Niggli, H.; Nowak, G.; Nunnemann, T.; Nyberg-Werther, M.; Oberlack, H.; Olsson, J. E.; Ozerov, D.; Palmen, P.; Panaro, E.; Panitch, A.; Pascaud, C.; Passaggio, S.; Patel, G. D.; Pawletta, H.; Peppel, E.; Perez, E.; Phillips, J. P.; Pieuchot, A.; Pitzl, D.; Pöschl, R.; Pope, G.; Povh, B.; Prell, S.; Rabbertz, K.; Rädel, G.; Reimer, P.; Rick, H.; Riess, S.; Rizvi, E.; Robmann, P.; Roosen, R.; Rosenbauer, K.; Rostovtsev, A.; Rouse, F.; Royon, C.; Rüter, K.; Rusakov, S.; Rybicki, K.; Sankey, D. P. C.; Schacht, P.; Schiek, S.; Schleif, S.; Schleper, P.; von Schlippe, W.; Schmidt, D.; Schmidt, G.; Schoeffel, L.; Schöning, A.; Schröder, V.; Schuhmann, E.; Schwab, B.; Sefkow, F.; Semenov, A.; Shekelyan, V.; Sheviakov, I.; Shtarkov, L. N.; Siegmon, G.; Siewert, U.; Sirois, Y.; Skillicorn, I. O.; Sloan, T.; Smirnov, P.; Smith, M.; Solochenko, V.; Soloviev, Y.; Specka, A.; Spiekermann, J.; Spielman, S.; Spitzer, H.; Squinabol, F.; Steffen, P.; Steinberg, R.; Steinhart, J.; Stella, B.; Stellberger, A.; Stier, J.; Stiewe, J.; Stöβlein, U.; Stolze, K.; Straumann, U.; Struczinski, W.; Sutton, J. P.; Tapprogge, S.; Taševský, M.; Tchernyshov, V.; Tchetchelnitski, S.; Theissen, J.; Thompson, G.; Thompson, P. D.; Tobien, N.; Todenhagen, R.; Truöl, P.; Tsipolitis, G.; Turnau, J.; Tzamariudaki, E.; Uelkes, P.; Usik, A.; Valkár, S.; Valkárová, A.; Valĺee, C.; Van Esch, P.; Van Mechelen, P.; Vandenplas, D.; Vazdik, Y.; Verrecchia, P.; Villet, G.; Wacker, K.; Wagener, A.; Wagener, M.; Wallny, R.; Waugh, B.; Weber, G.; Weber, M.; Wegener, D.; Wegner, A.; Wengler, T.; Werner, M.; West, L. R.; Wiesand, S.; Wilksen, T.; Willard, S.; Winde, M.; Winter, G.-G.; Wittek, C.; Wobisch, M.; Wollatz, H.; Wünsch, E.; Žáček, J.; Zarbock, D.; Zhang, Z.; Zhokin, A.; Zini, P.; Zomer, F.; Zsembery, J.; zurNedden, M.; H1 Collaboration

1997-02-01

The results of a measurement of the proton structure function F2( x, Q2) and the virtual photon-proton cross section are reported for momentum transfers squared Q2 between 0.35 GeV 2 and 3.5 GeV 2 and for Bjorken- x values down to 6 × 10 -6 using data collected by the HERA experiment H1 in 1995. The data represent an increase in kinematic reach to lower x and Q2 values of about a factor of 5 compared to previous H1 measurements. Including measurements from fixed target experiments the rise of F2 with decreasing x is found to be less steep for the lowest Q2 values measured. Phenomenological models at low Q2 are compared with the data.

Silicon Nanowire Field Effect Transistor Sensors with Minimal Sensor to Sensor Variations and Enhanced Sensing Characteristics.

PubMed

Zafar, Sufi; D'Emic, Christopher; Jagtiani, Ashish; Kratschmer, Ernst; Miao, Xin; Zhu, Yu; Mo, Renee; Sosa, Norma; Hamann, Hendrik F; Shahidi, Ghavam; Riel, Heike

2018-06-22

Silicon nanowire field effect transistor (FET) sensors have demonstrated their ability for rapid and label free detection of proteins, nucleotide sequences, and viruses at ultralow concentrations with the potential to be a transformative diagnostic technology. Their nanoscale size gives them their unique ultralow detection ability but also makes their fabrication challenging with large sensor to sensor variations, thus limiting their commercial applications. In this work, a combined approach of nanofabrication, device simulation, materials and electrical characterization is applied towards identifying and improving fabrication steps that induce sensor to sensor variations. An enhanced complementary metal-oxide-semiconductor (CMOS) compatible process for fabricating silicon nanowire FET sensors is demonstrated. Nanowire (30 nm width) FETs with aqueous solution as gates are shown to have the Nernst limit sub-threshold swing SS = 60 mV/decade with ~1.7% variations, whereas literature values for SS are ≥ 80 mV/decade with larger (>10 times) variations. Also, their threshold voltage variations are significantly (~3 times) reduced, compared to literature values. Furthermore, these improved FETs have significantly reduced drain current hysteresis (~0.6 mV) and enhanced on-current to off-current ratios (~10 6 ). These improvements resulted in nanowire FET sensors with lowest (~3%) reported sensor to sensor variations, compared to literature studies. Also, these improved nanowire sensors have the highest reported sensitivity and enhanced signal to noise ratio with the lowest reported defect density of 1x10 18 eV -1 cm -3 in comparison to literature data. In summary, this work brings the nanowire sensor technology a step closer to commercial products for early diagnosis and monitoring of diseases.

More choice in health insurance marketplaces may reduce the value of the subsidies available to low-income enrollees.

PubMed

Taylor, Erin A; Saltzman, Evan; Bauhoff, Sebastian; Pacula, Rosalie L; Eibner, Christine

2015-01-01

Federal subsidies available to enrollees in health insurance Marketplaces are pegged to the premium of the second-lowest-cost silver plan available in each rating area (as defined by each state). People who qualify for the subsidy contribute a percentage of their income to purchase coverage, and the federal government covers the remaining cost up to the price of that premium. Because the number of plans offered and plan premiums vary substantially across rating areas, the effective value of the subsidy may vary geographically. We found that the availability of more plans in a rating area was associated with lower premiums but higher deductibles for enrollees in the second-lowest-cost silver plan. In rating areas with more than twenty plans, the average deductible in the second-lowest-cost silver plan was nearly $1,000 higher than it was in rating areas with fewer than thirteen plans. Because premium costs for second-lowest-cost silver plans are capped, deductibles may be a more salient measure of plan value for enrollees than premiums are. Greater standardization of plans or an alternative approach to calculating the subsidy could provide a more consistent benefit to enrollees across various rating areas. Project HOPE—The People-to-People Health Foundation, Inc.

J1154+2443: a low-redshift compact star-forming galaxy with a 46 per cent leakage of Lyman continuum photons

NASA Astrophysics Data System (ADS)

Izotov, Y. I.; Schaerer, D.; Worseck, G.; Guseva, N. G.; Thuan, T. X.; Verhamme, A.; Orlitová, I.; Fricke, K. J.

2018-03-01

We report the detection of the Lyman continuum (LyC) radiation of the compact star-forming galaxy (SFG) J1154+2443 observed with the Cosmic Origins Spectrograph (COS) onboard the Hubble Space Telescope. This galaxy, at a redshift of z = 0.3690, is characterized by a high emission-line flux ratio O32 = [O III] λ5007/[O II] λ3727 = 11.5. The escape fraction of the LyC radiation fesc(LyC) in this galaxy is 46 per cent, the highest value found so far in low-redshift SFGs and one of the highest values found in galaxies at any redshift. The narrow double-peaked Ly α emission line is detected in the spectrum of J1154+2443 with a separation between the peaks Vsep of 199 km s-1, one of the lowest known for Ly α-emitting galaxies, implying a high fesc(Ly α). Comparing the extinction-corrected Ly α/H β flux ratio with the case B value, we find fesc(Ly α) = 98 per cent. Our observations, combined with previous detections in the literature, reveal an increase of O32 with increasing fesc(LyC). We also find a tight anticorrelation between fesc(LyC) and Vsep. The surface brightness profile derived from the COS acquisition image reveals a bright star-forming region in the centre and an exponential disc in the outskirts with a disc scale length α = 1.09 kpc. J1154+2443, compared to other known low-redshift LyC leakers, is characterized by the lowest metallicity, 12+log O/H = 7.65 ± 0.01, the lowest stellar mass M⋆ = 108.20 M⊙, a similar star formation rate SFR = 18.9 M⊙ yr-1, and a high specific SFR of 1.2 × 10-7 yr-1.

Usefulness of the 6-minute walk test as a screening test for pulmonary arterial enlargement in COPD

PubMed Central

Oki, Yutaro; Kaneko, Masahiro; Fujimoto, Yukari; Sakai, Hideki; Misu, Shogo; Mitani, Yuji; Yamaguchi, Takumi; Yasuda, Hisafumi; Ishikawa, Akira

2016-01-01

Purpose Pulmonary hypertension and exercise-induced oxygen desaturation (EID) influence acute exacerbation of COPD. Computed tomography (CT)-detected pulmonary artery (PA) enlargement is independently associated with acute COPD exacerbations. Associations between PA to aorta (PA:A) ratio and EID in patients with COPD have not been reported. We hypothesized that the PA:A ratio correlated with EID and that results of the 6-minute walk test (6MWT) would be useful for predicting the risk associated with PA:A >1. Patients and methods We retrospectively measured lung function, 6MWT, emphysema area, and PA enlargement on CT in 64 patients with COPD. The patients were classified into groups with PA:A ≤1 and >1. Receiver-operating characteristic curves were used to determine the threshold values with the best cutoff points to predict patients with PA:A >1. Results The PA:A >1 group had lower forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), FEV1:FVC ratio, diffusion capacity of lung carbon monoxide, 6MW distance, and baseline peripheral oxygen saturation (SpO2), lowest SpO2, highest modified Borg scale results, percentage low-attenuation area, and history of acute COPD exacerbations ≤1 year, and worse BODE (Body mass index, airflow Obstruction, Dyspnea, and Exercise) index results (P<0.05). Predicted PA:A >1 was determined for SpO2 during 6MWT (best cutoff point 89%, area under the curve 0.94, 95% confidence interval 0.88–1). SpO2 <90% during 6MWT showed a sensitivity of 93.1, specificity of 94.3, positive predictive value of 93.1, negative predictive value of 94.3, positive likelihood ratio of 16.2, and negative likelihood ratio of 0.07. Conclusion Lowest SpO2 during 6MWT may predict CT-measured PA:A, and lowest SpO2 <89% during 6MWT is excellent for detecting pulmonary hypertension in COPD. PMID:27920514

Cell-Free DNA in Metastatic Colorectal Cancer: A Systematic Review and Meta-Analysis.

PubMed

Spindler, Karen-Lise G; Boysen, Anders K; Pallisgård, Niels; Johansen, Julia S; Tabernero, Josep; Sørensen, Morten M; Jensen, Benny V; Hansen, Torben F; Sefrioui, David; Andersen, Rikke F; Brandslund, Ivan; Jakobsen, Anders

2017-09-01

Circulating DNA can be detected and quantified in the blood of cancer patients and used for detection of tumor-specific genetic alterations. The clinical utility has been intensively investigated for the past 10 years. The majority of reports focus on analyzing the clinical potential of tumor-specific mutations, whereas the use of total cell-free DNA (cfDNA) quantification is somehow controversial and sparsely described in the literature, but holds important clinical information in itself. The purpose of the present report was to present a systematic review and meta-analysis of the prognostic value of total cfDNA in patients with metastatic colorectal cancer (mCRC) treated with chemotherapy. In addition, we report on the overall performance of cfDNA as source for KRAS mutation detection. A systematic literature search of PubMed and Embase was performed by two independent investigators. Eligibility criteria were (a) total cfDNA analysis, (b) mCRC, and (c) prognostic value during palliative treatment. The preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines were followed, and meta-analysis applied on both aggregate data extraction and individual patients' data. Ten eligible cohorts were identified, including a total of 1,076 patients. Seven studies used quantitative polymerase chain reaction methods, two BEAMing [beads, emulsification, amplification, and magnetics] technology, and one study digital droplet polymerase chain reaction. The baseline levels of cfDNA was similar in the presented studies, and all studies reported a clear prognostic value in favor of patients with lowest levels of baseline cfDNA. A meta-analysis revealed a combined estimate of favorable overall survival hazard ratio (HR) in patients with levels below the median cfDNA (HR = 2.39, 95% confidence interval 2.03-2.82, p  < .0001). The total cfDNA levels are high in patients with mCRC and bear strong prognostic information, which should be tested prospectively by using a predefined cut-off value based on normal values in healthy cohorts. Finally, the potential use of cfDNA for detection of tumor-specific mutations was emphasized in a large individual patients' data meta-analysis. Reliable prognostic markers could help to guide patients and treating physicians regarding the relevance and choice of systemic therapy. Small fragments of circulating cell-free DNA (cfDNA) can be measured in a simple blood sample. This report presents the first meta-analysis of the prognostic value of total cfDNA measurement in patients with metastatic colorectal cancer. Data from 1,076 patients confirmed that patients with the lowest pre-treatment levels of cfDNA had a significantly higher chance of longer survival than those with higher levels. Cell-free DNA analysis can also be used for detection of tumor-specific mutations, and hold potential as a valuable tool in colorectal cancer treatment. © AlphaMed Press 2017.

Brain natriuretic peptide (BNP) may play a major role in risk stratification based on cerebral oxygen saturation by near-infrared spectroscopy in patients undergoing major cardiovascular surgery

PubMed Central

Hayashida, Masakazu; Matsushita, Satoshi; Yamamoto, Makiko; Nakamura, Atsushi; Amano, Atsushi

2017-01-01

Purpose A previous study reported that low baseline cerebral oxygen saturation (ScO2) (≤50%) measured with near-infrared spectroscopy was predictive of poor clinical outcomes after cardiac surgery. However, such findings have not been reconfirmed by others. We conducted the current study to evaluate whether the previous findings would be reproducible, and to explore mechanisms underlying the ScO2-based outcome prediction. Methods We retrospectively investigated 573 consecutive patients, aged 20 to 91 (mean ± standard deviation, 67.1 ± 12.8) years, who underwent major cardiovascular surgery. Preanesthetic baseline ScO2, lowest intraoperative ScO2, various clinical variables, and hospital mortality were examined. Results Bivariate regression analyses revealed that baseline ScO2 correlated significantly with plasma brain natriuretic peptide concentration (BNP), hemoglobin concentration (Hgb), estimated glomerular filtration rate (eGFR), and left ventricular ejection fraction (LVEF) (p < 0.0001 for each). Baseline ScO2 correlated with BNP in an exponential manner, and BNP was the most significant factor influencing ScO2. Logistic regression analyses revealed that baseline and lowest intraoperative ScO2 values, but not relative ScO2 decrements, were significantly associated with hospital mortality (p < 0.05), independent of the EuroSCORE (p < 0.01). Receiver operating curve analysis of ScO2 values and hospital mortality revealed an area under the curve (AUC) of 0.715 (p < 0.01) and a cutoff value of ≤50.5% for the baseline and ScO2, and an AUC of 0.718 (p < 0.05) and a cutoff value of ≤35% for the lowest intraoperative ScO2. Low baseline ScO2 (≤50%) was associated with increases in intubation time, intensive care unit stay, hospital stay, and hospital mortality. Conclusion Baseline ScO2 was reflective of severity of systemic comorbidities and was predictive of clinical outcomes after major cardiovascular surgery. ScO2 correlated most significantly with BNP in an exponential manner, suggesting that BNP plays a major role in the ScO2-based outcome prediction. PMID:28704502

Combined effect of pH and heating conditions on the physical properties of Alaska pollock surimi gels.

PubMed

Lee, Myeong Gi; Yoon, Won Byong; Park, Jae W

2017-06-01

Physical properties of Alaska pollock surimi paste were investigated as affected by pH (4.0 and 6.0-10.0) and heating conditions (slow and fast). The highest values of gel strength and deformability, as shown by breaking force and penetration distance, were obtained at pH 7.5-8.0, while the lowest values were at pH 10.0 followed by pH 6.0 and pH 6.5, respectively. Two-step slow heating process increased the breaking strength value nearly two times higher than one-step fast heating. The effect of pH was strikingly high at pH 7.5 when gels were prepared using 2-step heating, indicating the pH dependence of endogenous transglutaminase. However, the highest gel strength was obtained at pH 8.0 when gels were prepared in fast heating. Whiteness value (L - 3b*) increased significantly (p < .05) as pH increased from 6.0 to 6.5, but thereafter decreased significantly (p < .05) as pH increased. L* value (lightness) and b* value (yellowness) continuously decreased as the pH is shifted from 6.0 to 10. Fast heated gels showed the lowest yellowness, resulting in whiter appearance, probably due to the effect of reduced browning reaction. The uniqueness of this study was to measure the combined effect of pH and heating conditions on the gel texture and color. There were various studies dealing with pH or heating conditions independently. As the primary character for surimi seafood is gel texture and color. The highest values of gel strength and deformability, as shown by breaking force and penetration distance, were obtained at pH 7.5-8.0, while the lowest values were at pH 10.0 followed by pH 6.0 and pH 6.5, respectively. Two-step slow heating process increased the breaking strength value nearly two times higher than one-step fast heating. Whiteness value (L - 3b*) increased significantly as pH increased from 6.0 to 6.5, but thereafter decreased significantly as pH increased. L* value (lightness) and b* value (yellowness) continuously decreased as the pH is shifted from 6.0 to 10. Fast heated gels showed the lowest yellowness, resulting in whiter appearance. © 2016 Wiley Periodicals, Inc.

Culture and ethnicity influence outcomes of the Scoliosis Research Society Instrument in adolescent idiopathic scoliosis.

PubMed

Morse, Lee Jae; Kawakami, Noriaki; Lenke, Lawrence G; Sucato, Daniel J; Sanders, James O; Diab, Mohammad

2012-05-20

Retrospective comparative study. To report preoperative differences in the Scoliosis Research Society Outcomes Instrument (SRS-30) between multiple US ethnicities and native Japanese and Korean children with adolescent idiopathic scoliosis (AIS). The SRS-24 was developed in a US cohort with AIS. Comparative studies using the SRS-24 between US and Japanese patients showed differences, suggesting that culture might affect functional outcome. Preoperative SRS-30 outcomes were collected from 1853 children with AIS from 6 different ethnic groups: US white (1234), black (213), Hispanic (78), and Asian (29), as well as native Japanese (192) and Koreans (107). Analysis of covariance of 4 SRS-30 domains (pain, appearance, activity, and mental) was compared between groups adjusting for differences in age, sex, major curve magnitude, and body mass index. Pairwise comparisons of the 4 SRS-30 domains were adjusted for multiple comparisons, using Bonferroni correction. A P value of less than 0.05 was considered significant. Significant differences between ethnicities were found in all domains (P < 0.001). Whites reported more pain than Japanese or Koreans (Japanese = 4.52, Korean = 4.47, white = 4.04). Korean and Japanese patients had the lowest appearance scores (Japanese = 2.89, Korean = 2.73, US Asian = 3.55, Hispanic = 3.11, black = 3.47, white = 3.29). Koreans also had the lowest activity (Korean = 3.64, Japanese = 4.24, US Asian = 4.07, Hispanic = 4.02, black = 4.06, white = 4.16), mental (Korean = 3.70, Japanese = 4.23, US Asian = 4.05, Hispanic = 3.75, black = 4.03, white = 3.94), and total scores (Korean = 3.63, Japanese = 3.92, US Asian = 4.02, Hispanic = 3.75, black = 3.92, and white = 3.84). Culture and ethnicity influence SRS-30 outcomes in AIS. Whites reported more pain than Japanese and Koreans. Japanese and Koreans had the lowest appearance scores. Koreans additionally were distinguished by the lowest activity, mental, and total scores. These cultural and ethnic differences must be taken into account when counseling patients with AIS and studying functional outcomes.

Sensitivity of some nitrogen fixers and the target pest Fusarium oxysporum to fungicide thiram.

PubMed

Osman, Awad G; Sherif, Ashraf M; Elhussein, Adil A; Mohamed, Afrah T

2012-03-01

This study was carried out to investigate the toxic effects of the fungicide thiram (TMTD) against five nitrogen fixers and the thiram target pest Fusarium oxysporum under laboratory conditions. Nitrogen fixing bacteria Falvobacterium showed the highest values of LD(50) and proved to be the most resistant to the fungicide followed by Fusarium oxysporum, while Pseudomonas aurentiaca was the most affected microorganism. LD(50) values for these microorganisms were in 2-5 orders of magnitude lower in comparison with LD(50) value for Fusarium oxysporum. Thiram was most toxic to Pseudomonas aurentiaca followed by Azospirillum. The lowest toxicity index was recorded for Fusarium oxysporum and Flavobacterium. The slope of the curve for Azomonas, Fusarium oxysporum and Flavobacterium is more steep than that of the other curves, suggesting that even a slight increase of the dose of the fungicide can cause a very strong negative effect. Thiram was more selective to Pseudomonas aurentiaca followed by Azospirillum, Rhizobium meliloti and Azomonas. The lowest selectivity index of the fungicide was recorded for Falvobacterium followed by Fusarium oxysporum. The highest safety coefficient of the fungicide was assigned for Flavobacterium, while Pseudomonas aurentiaca showed the lowest value.

Effects of Surface Nonuniformities on the Mean Transverse Energy from Photocathodes

NASA Astrophysics Data System (ADS)

Karkare, Siddharth; Bazarov, Ivan

2015-08-01

The performance of photoinjectors is limited by the lowest value of the mean transverse energy of the electrons obtained from photocathodes. The factors that influence the mean transverse energy are poorly understood. In this paper, we develop models to calculate the effect of spatial work-function variations and subnanometer-scale roughness and surface defects on the mean transverse energy. We show that these can limit the lowest value of mean transverse energy achieved and that atomically perfect surfaces will be required to further reduce the mean transverse energy obtained from photocathodes.

STATISTICAL PROCEDURES FOR DETERMINATION AND VERIFICATION OF MINIMUM REPORTING LEVELS FOR DRINKING WATER METHODS

EPA Science Inventory

The United States Environmental Protection Agency's (EPA) Office of Ground Water and Drinking Water (OGWDW) has developed a single-laboratory quantitation procedure: the lowest concentration minimum reporting level (LCMRL). The LCMRL is the lowest true concentration for which fu...

Color distribution of a shade guide in the value, chroma, and hue scale.

PubMed

Ahn, Jin-Soo; Lee, Yong-Keun

2008-07-01

Shade tabs in a shade guide are matched to teeth in the order of value, hue, and chroma; therefore, information on the distribution of shade tabs is essential for clinical application of a shade guide. However, there is limited information on the color distribution as sorted by these 3 parameters of a recently introduced shade guide. The purposes of this study were to determine the color distributions of tabs from a shade guide in the value (CIE L*), chroma (C*(ab)), and hue scale, and to determine the distribution of step intervals between adjacent tabs by value and chroma. The color of shade tabs (n=29) from a shade guide (Vitapan 3D-Master) was measured to determine the distribution of shade tabs by the value, chroma, hue angle, and CIE a* and b* values. The distribution of the ratios of the value and the chroma of each tab, when compared with the lowest value tab or the lowest chroma tab, was also determined. The data for each color parameter were analyzed by a 3-way ANOVA with the factors of value, chroma, and hue designations of the tabs (alpha=.05). The value, chroma, hue angle, and CIE a* and b* values were influenced by the value, chroma, and hue designations of shade tabs (P<.001). The distributions of the chroma of the tabs within the same value group were relatively ordered, but the values of different value groups overlapped in several instances. Distributions for the CIE a* and b* values reflected the chroma designations in each value group. In the same value group, L, M, and R hue designations corresponded with the manufacturer's stated hue, such as a yellow hue for the L designation and a red hue for the R designation. The distance in the value and chroma scales between adjacent tabs was not uniform. The color distribution of the Vitapan 3D-Master shade guide was more ordered than previously reported color distributions of other, traditional shade guides. However, the interval in the color parameters between adjacent tabs was not uniform; therefore, shade tabs spaced equally, according to the color parameters, should be studied based on the observer's response data.

Toxicological Benchmarks for Screening of Potential Contaminants of Concern for Effects on Aquatic Biota on the Oak Ridge Reservation, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Suter, G.W., II

1993-01-01

One of the initial stages in ecological risk assessment of hazardous waste sites is the screening of contaminants to determine which, if any, of them are worthy of further consideration; this process is termed contaminant screening. Screening is performed by comparing concentrations in ambient media to benchmark concentrations that are either indicative of a high likelihood of significant effects (upper screening benchmarks) or of a very low likelihood of significant effects (lower screening benchmarks). Exceedance of an upper screening benchmark indicates that the chemical in question is clearly of concern and remedial actions are likely to be needed. Exceedance ofmore » a lower screening benchmark indicates that a contaminant is of concern unless other information indicates that the data are unreliable or the comparison is inappropriate. Chemicals with concentrations below the lower benchmark are not of concern if the ambient data are judged to be adequate. This report presents potential screening benchmarks for protection of aquatic life from contaminants in water. Because there is no guidance for screening benchmarks, a set of alternative benchmarks is presented herein. The alternative benchmarks are based on different conceptual approaches to estimating concentrations causing significant effects. For the upper screening benchmark, there are the acute National Ambient Water Quality Criteria (NAWQC) and the Secondary Acute Values (SAV). The SAV concentrations are values estimated with 80% confidence not to exceed the unknown acute NAWQC for those chemicals with no NAWQC. The alternative chronic benchmarks are the chronic NAWQC, the Secondary Chronic Value (SCV), the lowest chronic values for fish and daphnids, the lowest EC20 for fish and daphnids from chronic toxicity tests, the estimated EC20 for a sensitive species, and the concentration estimated to cause a 20% reduction in the recruit abundance of largemouth bass. It is recommended that ambient chemical concentrations be compared to all of these benchmarks. If NAWQC are exceeded, the chemicals must be contaminants of concern because the NAWQC are applicable or relevant and appropriate requirements (ARARs). If NAWQC are not exceeded, but other benchmarks are, contaminants should be selected on the basis of the number of benchmarks exceeded and the conservatism of the particular benchmark values, as discussed in the text. To the extent that toxicity data are available, this report presents the alternative benchmarks for chemicals that have been detected on the Oak Ridge Reservation. It also presents the data used to calculate the benchmarks and the sources of the data. It compares the benchmarks and discusses their relative conservatism and utility. This report supersedes a prior aquatic benchmarks report (Suter and Mabrey 1994). It adds two new types of benchmarks. It also updates the benchmark values where appropriate, adds some new benchmark values, replaces secondary sources with primary sources, and provides more complete documentation of the sources and derivation of all values.« less

Yttrium Iron Garnet Thin Films with Very Low Damping Obtained by Recrystallization of Amorphous Material

PubMed Central

Hauser, Christoph; Richter, Tim; Homonnay, Nico; Eisenschmidt, Christian; Qaid, Mohammad; Deniz, Hakan; Hesse, Dietrich; Sawicki, Maciej; Ebbinghaus, Stefan G.; Schmidt, Georg

2016-01-01

We have investigated recrystallization of amorphous Yttrium Iron Garnet (YIG) by annealing in oxygen atmosphere. Our findings show that well below the melting temperature the material transforms into a fully epitaxial layer with exceptional quality, both structural and magnetic. In ferromagnetic resonance (FMR) ultra low damping and extremely narrow linewidth can be observed. For a 56 nm thick layer a damping constant of α = (6.15 ± 1.50) · 10−5 is found and the linewidth at 9.6 GHz is as small as 1.30 ± 0.05 Oe which are the lowest values for PLD grown thin films reported so far. Even for a 20 nm thick layer a damping constant of α = (7.35 ± 1.40) · 10−5 is found which is the lowest value for ultrathin films published so far. The FMR linewidth in this case is 3.49 ± 0.10 Oe at 9.6 GHz. Our results not only present a method of depositing thin film YIG of unprecedented quality but also open up new options for the fabrication of thin film complex oxides or even other crystalline materials. PMID:26860816

Assessing Clinical Laboratory Quality: A College of American Pathologists Q-Probes Study of Prothrombin Time INR Structures, Processes, and Outcomes in 98 Laboratories.

PubMed

Howanitz, Peter J; Darcy, Theresa P; Meier, Frederick A; Bashleben, Christine P

2015-09-01

The anticoagulant warfarin has been identified as the second most frequent drug responsible for serious, disabling, and fatal adverse drug events in the United States, and its effect on blood coagulation is monitored by the laboratory test called international normalized ratio (INR). To determine the presence of INR policies and procedures, INR practices, and completeness and timeliness of reporting critical INR results in participants' clinical laboratories. Participants reviewed their INR policies and procedure requirements, identified their practices by using a questionnaire, and studied completeness of documentation and timeliness of reporting critical value INR results for outpatients and emergency department patients. In 98 participating institutions, the 5 required policies and procedures were in place in 93% to 99% of clinical laboratories. Fifteen options for the allowable variations among duplicate results from different analyzers, 12 different timeliness goals for reporting critical values, and 18 unique critical value limits were used by participants. All required documentation elements were present in 94.8% of 192 reviewed INR validation reports. Critical value INR results were reported within the time frame established by the laboratory for 93.4% of 2604 results, but 1.0% of results were not reported. Although the median laboratories successfully communicated all critical results within their established time frames and had all the required validation elements based in their 2 most recent INR calculations, those participants at the lowest 10th percentile were successful in 80.0% and 85.7% of these requirements, respectively. Significant opportunities exist for adherence to INR procedural requirements and for practice patterns and timeliness goals for INR critical results' reporting.

Circadian rhythm of blood and urinary copper in presumably healthy subjects of vegetarian food habit

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhattacharya, R.D.

Circadian rhythm of blood and urinary copper has been studied in presumably healthy subjects of a particular ethnic group in India who are vegetarians. A definite 24-hr variation has been observed for both blood and urinary copper. The peak for blood copper was 1500 hr and the lowest value was 0600 hr, with values of 0.185 mg/100 ml and 0.160 mg/100 ml respectively. The urinary peak and trough occurred at 0600 and 0300 hr, respectively. Remarkably higher 24-hr copper excretion values were noted (64.49 ..mu..g/day) with a range of 15-100 ..mu..g/day. The blood level of copper (0.134 mg/100 ml) remainedmore » within the range reported. One subject out of 25 deviated from the group with respect to circadian phasing and amplitude to urinary copper excretion. 20 references.« less

Alkaline precipitation in Bahia Blanca, Argentina

DOE Office of Scientific and Technical Information (OSTI.GOV)

Piccolo, M.C.; Perillo, G.M.E.; Varela, P.

1988-02-01

The spatial, meteorological, and seasonal factors associated with precipitation pH in Bahia Blanca and its surroundings are presented. From April 1984 to April 1985, 85 rain events were studied from 12 sites that represent significant land-use sectors of the city. Mean pH for all sites ranged from 6.5 to 7.2. The area is characterized by alkaline precipitation since most stations reported maximum values in excess of 7.6. The highest values of pH were observed under the influence of continental air masses, which have traveled over the pampas soil, thus introducing large amounts of alkaline cations. The lowest pH values weremore » obtained during the winter season when marine advection introduces high concentrations of spray. Stations located close to the estuary and the industrial park present the larger effect of sea spray but also of the incidence of an incipient atmospheric contamination.« less

Self-reported hepatitis A vaccination as a predictor of hepatitis A virus antibody protection in U.S. adults: National Health and Nutrition Examination Survey 2007-2012.

PubMed

Denniston, Maxine M; Monina Klevens, R; Jiles, Ruth B; Murphy, Trudy V

2015-07-31

To estimate the predictive value of self-reported hepatitis A vaccine (HepA) receipt for the presence of hepatitis A virus (HAV) antibody (anti-HAV) from either past infection or vaccination, as an indicator of HAV protection. Using 2007-2012 National Health and Nutrition Examination Survey data, we assigned participants to 4 groups based on self-reported HepA receipt and anti-HAV results. We compared characteristics across groups and calculated three measures of agreement between self-report and serologic status (anti-HAV): percentage concordance, and positive (PPV) and negative (NPV) predictive values. Using logistic regression we investigated factors associated with agreement between self-reported vaccination status and serological results. Demographic and other characteristics varied significantly across the 4 groups. Overall agreement between self-reported HepA receipt and serological results was 63.6% (95% confidence interval [CI] 61.9-65.2); PPV and NPV of self-reported vaccination status for serological result were 47.0% (95% CI 44.2-49.8) and 69.4% (95% CI 67.0-71.8), respectively. Mexican American and foreign-born adults had the highest PPVs (71.5% [95% CI 65.9-76.5], and 75.8% [95% CI 71.4-79.7]) and the lowest NPVs (21.8% [95% CI 18.5-25.4], and 20.0% [95% CI 17.2-23.1]), respectively. Young (ages 20-29 years), US-born, and non-Hispanic White adults had the lowest PPVs (37.9% [95% CI 34.5-41.5], 39.1% [95% CI, 36.0-42.3], and 39.8% [36.1-43.7]), and the highest NPVs (76.9% [95% CI 72.2-81.0, 78.5% [95% CI 76.5-80.4)], and 80.6% [95% CI 78.2-82.8), respectively. Multivariate logistic analyses found age, race/ethnicity, education, place of birth and income to be significantly associated with agreement between self-reported vaccination status and serological results. When assessing hepatitis A protection, self-report of not having received HepA was most likely to identify persons at risk for hepatitis A infection (no anti-HAV) among young, US-born and non-Hispanic White adults, and self-report of HepA receipt was least likely to be reliable among adults with the same characteristics. Copyright © 2015. Published by Elsevier Ltd.

Seasonal variability of equilibrium factor and unattached fractions of radon and thoron in different regions of Punjab, India.

PubMed

Saini, Komal; Singh, Parminder; Singh, Prabhjot; Bajwa, B S; Sahoo, B K

2017-02-01

A survey was conducted to estimate equilibrium factor and unattached fractions of radon and thoron in different regions of Punjab state, India. Pin hole based twin cup dosimeters and direct progeny sensor techniques have been utilized for estimation of concentration level of radon, thoron and their progenies. Equilibrium factor calculated from radon, thoron and their progenies concentration has been found to vary from 0.15 to 0.80 and 0.008 to 0.101 with an average value of 0.44 and 0.036 for radon and thoron respectively. Equilibrium factor for radon has found to be highest in winter season and lowest in summer season whereas for thoron highest value is observed in winter and rainy season and lowest in summer. Unattached fractions of radon and thoron have been found to vary from 0.022 to 0.205 and 0.013 to 0.212 with an average value of 0.099 and 0.071 respectively. Unattached fractions have found to be highest in winter season and lowest in rainy and summer season. Copyright © 2016 Elsevier Ltd. All rights reserved.

All-sky search for periodic gravitational waves in the O1 LIGO data

NASA Astrophysics Data System (ADS)

Abbott, B. P.; Abbott, R.; Abbott, T. D.; Acernese, F.; Ackley, K.; Adams, C.; Adams, T.; Addesso, P.; Adhikari, R. X.; Adya, V. B.; Affeldt, C.; Afrough, M.; Agarwal, B.; Agatsuma, K.; Aggarwal, N.; Aguiar, O. D.; Aiello, L.; Ain, A.; Ajith, P.; Allen, B.; Allen, G.; Allocca, A.; Altin, P. A.; Amato, A.; Ananyeva, A.; Anderson, S. B.; Anderson, W. G.; Antier, S.; Appert, S.; Arai, K.; Araya, M. C.; Areeda, J. S.; Arnaud, N.; Ascenzi, S.; Ashton, G.; Ast, M.; Aston, S. M.; Astone, P.; Aufmuth, P.; Aulbert, C.; AultONeal, K.; Avila-Alvarez, A.; Babak, S.; Bacon, P.; Bader, M. K. M.; Bae, S.; Baker, P. T.; Baldaccini, F.; Ballardin, G.; Ballmer, S. W.; Banagiri, S.; Barayoga, J. C.; Barclay, S. E.; Barish, B. C.; Barker, D.; Barone, F.; Barr, B.; Barsotti, L.; Barsuglia, M.; Barta, D.; Bartlett, J.; Bartos, I.; Bassiri, R.; Basti, A.; Batch, J. C.; Baune, C.; Bawaj, M.; Bazzan, M.; Bécsy, B.; Beer, C.; Bejger, M.; Belahcene, I.; Bell, A. S.; Berger, B. K.; Bergmann, G.; Berry, C. P. L.; Bersanetti, D.; Bertolini, A.; Betzwieser, J.; Bhagwat, S.; Bhandare, R.; Bilenko, I. A.; Billingsley, G.; Billman, C. R.; Birch, J.; Birney, R.; Birnholtz, O.; Biscans, S.; Bisht, A.; Bitossi, M.; Biwer, C.; Bizouard, M. A.; Blackburn, J. K.; Blackman, J.; Blair, C. D.; Blair, D. G.; Blair, R. M.; Bloemen, S.; Bock, O.; Bode, N.; Boer, M.; Bogaert, G.; Bohe, A.; Bondu, F.; Bonnand, R.; Boom, B. A.; Bork, R.; Boschi, V.; Bose, S.; Bouffanais, Y.; Bozzi, A.; Bradaschia, C.; Brady, P. R.; Braginsky, V. B.; Branchesi, M.; Brau, J. E.; Briant, T.; Brillet, A.; Brinkmann, M.; Brisson, V.; Brockill, P.; Broida, J. E.; Brooks, A. F.; Brown, D. A.; Brown, D. D.; Brown, N. M.; Brunett, S.; Buchanan, C. C.; Buikema, A.; Bulik, T.; Bulten, H. J.; Buonanno, A.; Buskulic, D.; Buy, C.; Byer, R. L.; Cabero, M.; Cadonati, L.; Cagnoli, G.; Cahillane, C.; Calderón Bustillo, J.; Callister, T. A.; Calloni, E.; Camp, J. B.; Canizares, P.; Cannon, K. C.; Cao, H.; Cao, J.; Capano, C. D.; Capocasa, E.; Carbognani, F.; Caride, S.; Carney, M. F.; Casanueva Diaz, J.; Casentini, C.; Caudill, S.; Cavaglià, M.; Cavalier, F.; Cavalieri, R.; Cella, G.; Cepeda, C. B.; Cerboni Baiardi, L.; Cerretani, G.; Cesarini, E.; Chamberlin, S. J.; Chan, M.; Chao, S.; Charlton, P.; Chassande-Mottin, E.; Chatterjee, D.; Cheeseboro, B. D.; Chen, H. Y.; Chen, Y.; Cheng, H.-P.; Chincarini, A.; Chiummo, A.; Chmiel, T.; Cho, H. S.; Cho, M.; Chow, J. H.; Christensen, N.; Chu, Q.; Chua, A. J. K.; Chua, S.; Chung, A. K. W.; Chung, S.; Ciani, G.; Ciecielag, P.; Ciolfi, R.; Cirelli, C. E.; Cirone, A.; Clara, F.; Clark, J. A.; Cleva, F.; Cocchieri, C.; Coccia, E.; Cohadon, P.-F.; Colla, A.; Collette, C. G.; Cominsky, L. R.; Constancio, M.; Conti, L.; Cooper, S. J.; Corban, P.; Corbitt, T. R.; Corley, K. R.; Cornish, N.; Corsi, A.; Cortese, S.; Costa, C. A.; Coughlin, E.; Coughlin, M. W.; Coughlin, S. B.; Coulon, J.-P.; Countryman, S. T.; Couvares, P.; Covas, P. B.; Cowan, E. E.; Coward, D. M.; Cowart, M. J.; Coyne, D. C.; Coyne, R.; Creighton, J. D. E.; Creighton, T. D.; Cripe, J.; Crowder, S. G.; Cullen, T. J.; Cumming, A.; Cunningham, L.; Cuoco, E.; Canton, T. Dal; Danilishin, S. L.; D'Antonio, S.; Danzmann, K.; Dasgupta, A.; Da Silva Costa, C. F.; Dattilo, V.; Dave, I.; Davier, M.; Davis, D.; Daw, E. J.; Day, B.; De, S.; DeBra, D.; Deelman, E.; Degallaix, J.; De Laurentis, M.; Deléglise, S.; Del Pozzo, W.; Denker, T.; Dent, T.; Dergachev, V.; De Rosa, R.; DeRosa, R. T.; DeSalvo, R.; Devenson, J.; Devine, R. C.; Dhurandhar, S.; Díaz, M. C.; Di Fiore, L.; Di Giovanni, M.; Di Girolamo, T.; Di Lieto, A.; Di Pace, S.; Di Palma, I.; Di Renzo, F.; Doctor, Z.; Dolique, V.; Donovan, F.; Dooley, K. L.; Doravari, S.; Dorosh, O.; Dorrington, I.; Douglas, R.; Dovale Álvarez, M.; Downes, T. P.; Drago, M.; Drever, R. W. P.; Driggers, J. C.; Du, Z.; Ducrot, M.; Duncan, J.; Dwyer, S. E.; Edo, T. B.; Edwards, M. C.; Effler, A.; Eggenstein, H.-B.; Ehrens, P.; Eichholz, J.; Eikenberry, S. S.; Eisenstein, R. A.; Essick, R. C.; Etienne, Z. B.; Etzel, T.; Evans, M.; Evans, T. M.; Factourovich, M.; Fafone, V.; Fair, H.; Fairhurst, S.; Fan, X.; Farinon, S.; Farr, B.; Farr, W. M.; Fauchon-Jones, E. J.; Favata, M.; Fays, M.; Fehrmann, H.; Feicht, J.; Fejer, M. M.; Fernandez-Galiana, A.; Ferrante, I.; Ferreira, E. C.; Ferrini, F.; Fidecaro, F.; Fiori, I.; Fiorucci, D.; Fisher, R. P.; Flaminio, R.; Fletcher, M.; Fong, H.; Forsyth, P. W. F.; Forsyth, S. S.; Fournier, J.-D.; Frasca, S.; Frasconi, F.; Frei, Z.; Freise, A.; Frey, R.; Frey, V.; Fries, E. M.; Fritschel, P.; Frolov, V. V.; Fulda, P.; Fyffe, M.; Gabbard, H.; Gabel, M.; Gadre, B. U.; Gaebel, S. M.; Gair, J. R.; Gammaitoni, L.; Ganija, M. R.; Gaonkar, S. G.; Garufi, F.; Gaudio, S.; Gaur, G.; Gayathri, V.; Gehrels, N.; Gemme, G.; Genin, E.; Gennai, A.; George, D.; George, J.; Gergely, L.; Germain, V.; Ghonge, S.; Ghosh, Abhirup; Ghosh, Archisman; Ghosh, S.; Giaime, J. A.; Giardina, K. D.; Giazotto, A.; Gill, K.; Glover, L.; Goetz, E.; Goetz, R.; Gomes, S.; González, G.; Gonzalez Castro, J. M.; Gopakumar, A.; Gorodetsky, M. L.; Gossan, S. E.; Gosselin, M.; Gouaty, R.; Grado, A.; Graef, C.; Granata, M.; Grant, A.; Gras, S.; Gray, C.; Greco, G.; Green, A. C.; Groot, P.; Grote, H.; Grunewald, S.; Gruning, P.; Guidi, G. M.; Guo, X.; Gupta, A.; Gupta, M. K.; Gushwa, K. E.; Gustafson, E. K.; Gustafson, R.; Hall, B. R.; Hall, E. D.; Hammond, G.; Haney, M.; Hanke, M. M.; Hanks, J.; Hanna, C.; Hannuksela, O. A.; Hanson, J.; Hardwick, T.; Harms, J.; Harry, G. M.; Harry, I. W.; Hart, M. J.; Haster, C.-J.; Haughian, K.; Healy, J.; Heidmann, A.; Heintze, M. C.; Heitmann, H.; Hello, P.; Hemming, G.; Hendry, M.; Heng, I. S.; Hennig, J.; Henry, J.; Heptonstall, A. W.; Heurs, M.; Hild, S.; Hoak, D.; Hofman, D.; Holt, K.; Holz, D. E.; Hopkins, P.; Horst, C.; Hough, J.; Houston, E. A.; Howell, E. J.; Hu, Y. M.; Huerta, E. A.; Huet, D.; Hughey, B.; Husa, S.; Huttner, S. H.; Huynh-Dinh, T.; Indik, N.; Ingram, D. R.; Inta, R.; Intini, G.; Isa, H. N.; Isac, J.-M.; Isi, M.; Iyer, B. R.; Izumi, K.; Jacqmin, T.; Jani, K.; Jaranowski, P.; Jawahar, S.; Jiménez-Forteza, F.; Johnson, W. W.; Jones, D. I.; Jones, R.; Jonker, R. J. G.; Ju, L.; Junker, J.; Kalaghatgi, C. V.; Kalogera, V.; Kandhasamy, S.; Kang, G.; Kanner, J. B.; Karki, S.; Karvinen, K. S.; Kasprzack, M.; Katolik, M.; Katsavounidis, E.; Katzman, W.; Kaufer, S.; Kawabe, K.; Kéfélian, F.; Keitel, D.; Kemball, A. J.; Kennedy, R.; Kent, C.; Key, J. S.; Khalili, F. Y.; Khan, I.; Khan, S.; Khan, Z.; Khazanov, E. A.; Kijbunchoo, N.; Kim, Chunglee; Kim, J. C.; Kim, W.; Kim, W. S.; Kim, Y.-M.; Kimbrell, S. J.; King, E. J.; King, P. J.; Kirchhoff, R.; Kissel, J. S.; Kleybolte, L.; Klimenko, S.; Koch, P.; Koehlenbeck, S. M.; Koley, S.; Kondrashov, V.; Kontos, A.; Korobko, M.; Korth, W. Z.; Kowalska, I.; Kozak, D. B.; Krämer, C.; Kringel, V.; Krishnan, B.; Królak, A.; Kuehn, G.; Kumar, P.; Kumar, R.; Kumar, S.; Kuo, L.; Kutynia, A.; Kwang, S.; Lackey, B. D.; Lai, K. H.; Landry, M.; Lang, R. N.; Lange, J.; Lantz, B.; Lanza, R. K.; Lartaux-Vollard, A.; Lasky, P. D.; Laxen, M.; Lazzarini, A.; Lazzaro, C.; Leaci, P.; Leavey, S.; Lee, C. H.; Lee, H. K.; Lee, H. M.; Lee, H. W.; Lee, K.; Lehmann, J.; Lenon, A.; Leonardi, M.; Leroy, N.; Letendre, N.; Levin, Y.; Li, T. G. F.; Libson, A.; Littenberg, T. B.; Liu, J.; Liu, W.; Lo, R. K. L.; Lockerbie, N. A.; London, L. T.; Lord, J. E.; Lorenzini, M.; Loriette, V.; Lormand, M.; Losurdo, G.; Lough, J. D.; Lovelace, G.; Lück, H.; Lumaca, D.; Lundgren, A. P.; Lynch, R.; Ma, Y.; Macfoy, S.; Machenschalk, B.; MacInnis, M.; Macleod, D. M.; Magaña Hernandez, I.; Magaña-Sandoval, F.; Magaña Zertuche, L.; Magee, R. M.; Majorana, E.; Maksimovic, I.; Man, N.; Mandic, V.; Mangano, V.; Mansell, G. L.; Manske, M.; Mantovani, M.; Marchesoni, F.; Marion, F.; Márka, S.; Márka, Z.; Markakis, C.; Markosyan, A. S.; Maros, E.; Martelli, F.; Martellini, L.; Martin, I. W.; Martynov, D. V.; Marx, J. N.; Mason, K.; Masserot, A.; Massinger, T. J.; Masso-Reid, M.; Mastrogiovanni, S.; Matas, A.; Matichard, F.; Matone, L.; Mavalvala, N.; Mayani, R.; Mazumder, N.; McCarthy, R.; McClelland, D. E.; McCormick, S.; McCuller, L.; McGuire, S. C.; McIntyre, G.; McIver, J.; McManus, D. J.; McRae, T.; McWilliams, S. T.; Meacher, D.; Meadors, G. D.; Meidam, J.; Mejuto-Villa, E.; Melatos, A.; Mendell, G.; Mercer, R. A.; Merilh, E. L.; Merzougui, M.; Meshkov, S.; Messenger, C.; Messick, C.; Metzdorff, R.; Meyers, P. M.; Mezzani, F.; Miao, H.; Michel, C.; Middleton, H.; Mikhailov, E. E.; Milano, L.; Miller, A. L.; Miller, A.; Miller, B. B.; Miller, J.; Millhouse, M.; Minazzoli, O.; Minenkov, Y.; Ming, J.; Mishra, C.; Mitra, S.; Mitrofanov, V. P.; Mitselmakher, G.; Mittleman, R.; Moggi, A.; Mohan, M.; Mohapatra, S. R. P.; Montani, M.; Moore, B. C.; Moore, C. J.; Moraru, D.; Moreno, G.; Morriss, S. R.; Mours, B.; Mow-Lowry, C. M.; Mueller, G.; Muir, A. W.; Mukherjee, Arunava; Mukherjee, D.; Mukherjee, S.; Mukund, N.; Mullavey, A.; Munch, J.; Muniz, E. A. M.; Murray, P. G.; Napier, K.; Nardecchia, I.; Naticchioni, L.; Nayak, R. K.; Nelemans, G.; Nelson, T. J. N.; Neri, M.; Nery, M.; Neunzert, A.; Newport, J. M.; Newton, G.; Ng, K. K. Y.; Nguyen, T. T.; Nichols, D.; Nielsen, A. B.; Nissanke, S.; Nitz, A.; Noack, A.; Nocera, F.; Nolting, D.; Normandin, M. E. N.; Nuttall, L. K.; Oberling, J.; Ochsner, E.; Oelker, E.; Ogin, G. H.; Oh, J. J.; Oh, S. H.; Ohme, F.; Oliver, M.; Oppermann, P.; Oram, Richard J.; O'Reilly, B.; Ormiston, R.; Ortega, L. F.; O'Shaughnessy, R.; Ottaway, D. J.; Overmier, H.; Owen, B. J.; Pace, A. E.; Page, J.; Page, M. A.; Pai, A.; Pai, S. A.; Palamos, J. R.; Palashov, O.; Palomba, C.; Pal-Singh, A.; Pan, H.; Pang, B.; Pang, P. T. H.; Pankow, C.; Pannarale, F.; Pant, B. C.; Paoletti, F.; Paoli, A.; Papa, M. A.; Paris, H. R.; Parker, W.; Pascucci, D.; Pasqualetti, A.; Passaquieti, R.; Passuello, D.; Patricelli, B.; Pearlstone, B. L.; Pedraza, M.; Pedurand, R.; Pekowsky, L.; Pele, A.; Penn, S.; Perez, C. J.; Perreca, A.; Perri, L. M.; Pfeiffer, H. P.; Phelps, M.; Piccinni, O. J.; Pichot, M.; Piergiovanni, F.; Pierro, V.; Pillant, G.; Pinard, L.; Pinto, I. M.; Pisarski, A.; Pitkin, M.; Poggiani, R.; Popolizio, P.; Porter, E. K.; Post, A.; Powell, J.; Prasad, J.; Pratt, J. W. W.; Predoi, V.; Prestegard, T.; Prijatelj, M.; Principe, M.; Privitera, S.; Prix, R.; Prodi, G. A.; Prokhorov, L. G.; Puncken, O.; Punturo, M.; Puppo, P.; Pürrer, M.; Qi, H.; Qin, J.; Qiu, S.; Quetschke, V.; Quintero, E. A.; Quitzow-James, R.; Raab, F. J.; Rabeling, D. S.; Radkins, H.; Raffai, P.; Raja, S.; Rajan, C.; Rakhmanov, M.; Ramirez, K. E.; Rapagnani, P.; Raymond, V.; Razzano, M.; Read, J.; Regimbau, T.; Rei, L.; Reid, S.; Reitze, D. H.; Rew, H.; Reyes, S. D.; Ricci, F.; Ricker, P. M.; Rieger, S.; Riles, K.; Rizzo, M.; Robertson, N. A.; Robie, R.; Robinet, F.; Rocchi, A.; Rolland, L.; Rollins, J. G.; Roma, V. J.; Romano, R.; Romel, C. L.; Romie, J. H.; Rosińska, D.; Ross, M. P.; Rowan, S.; Rüdiger, A.; Ruggi, P.; Ryan, K.; Rynge, M.; Sachdev, S.; Sadecki, T.; Sadeghian, L.; Sakellariadou, M.; Salconi, L.; Saleem, M.; Salemi, F.; Samajdar, A.; Sammut, L.; Sampson, L. M.; Sanchez, E. J.; Sandberg, V.; Sandeen, B.; Sanders, J. R.; Sassolas, B.; Saulson, P. R.; Sauter, O.; Savage, R. L.; Sawadsky, A.; Schale, P.; Scheuer, J.; Schmidt, E.; Schmidt, J.; Schmidt, P.; Schnabel, R.; Schofield, R. M. S.; Schönbeck, A.; Schreiber, E.; Schuette, D.; Schulte, B. W.; Schutz, B. F.; Schwalbe, S. G.; Scott, J.; Scott, S. M.; Seidel, E.; Sellers, D.; Sengupta, A. S.; Sentenac, D.; Sequino, V.; Sergeev, A.; Shaddock, D. A.; Shaffer, T. J.; Shah, A. A.; Shahriar, M. S.; Shao, L.; Shapiro, B.; Shawhan, P.; Sheperd, A.; Shoemaker, D. H.; Shoemaker, D. M.; Siellez, K.; Siemens, X.; Sieniawska, M.; Sigg, D.; Silva, A. D.; Singer, A.; Singer, L. P.; Singh, A.; Singh, R.; Singhal, A.; Sintes, A. M.; Slagmolen, B. J. J.; Smith, B.; Smith, J. R.; Smith, R. J. E.; Son, E. J.; Sonnenberg, J. A.; Sorazu, B.; Sorrentino, F.; Souradeep, T.; Spencer, A. P.; Srivastava, A. K.; Staley, A.; Steinke, M.; Steinlechner, J.; Steinlechner, S.; Steinmeyer, D.; Stephens, B. C.; Stone, R.; Strain, K. A.; Stratta, G.; Strigin, S. E.; Sturani, R.; Stuver, A. L.; Summerscales, T. Z.; Sun, L.; Sunil, S.; Sutton, P. J.; Swinkels, B. L.; Szczepańczyk, M. J.; Tacca, M.; Talukder, D.; Tanner, D. B.; Tao, D.; Tápai, M.; Taracchini, A.; Taylor, J. A.; Taylor, R.; Theeg, T.; Thomas, E. G.; Thomas, M.; Thomas, P.; Thorne, K. A.; Thorne, K. S.; Thrane, E.; Tiwari, S.; Tiwari, V.; Tokmakov, K. V.; Toland, K.; Tonelli, M.; Tornasi, Z.; Torrie, C. I.; Töyrä, D.; Travasso, F.; Traylor, G.; Trembath-Reichert, S.; Trifirò, D.; Trinastic, J.; Tringali, M. C.; Trozzo, L.; Tsang, K. W.; Tse, M.; Tso, R.; Tuyenbayev, D.; Ueno, K.; Ugolini, D.; Unnikrishnan, C. S.; Urban, A. L.; Usman, S. A.; Vahi, K.; Vahlbruch, H.; Vajente, G.; Valdes, G.; Vallisneri, M.; van Bakel, N.; van Beuzekom, M.; van den Brand, J. F. J.; Van Den Broeck, C.; Vander-Hyde, D. C.; van der Schaaf, L.; van Heijningen, J. V.; van Veggel, A. A.; Vardaro, M.; Varma, V.; Vass, S.; Vasúth, M.; Vecchio, A.; Vedovato, G.; Veitch, J.; Veitch, P. J.; Venkateswara, K.; Venugopalan, G.; Verkindt, D.; Vetrano, F.; Viceré, A.; Viets, A. D.; Vinciguerra, S.; Vine, D. J.; Vinet, J.-Y.; Vitale, S.; Vo, T.; Vocca, H.; Vorvick, C.; Voss, D. V.; Vousden, W. D.; Vyatchanin, S. P.; Wade, A. R.; Wade, L. E.; Wade, M.; Walet, R.; Walker, M.; Wallace, L.; Walsh, S.; Wang, G.; Wang, H.; Wang, J. Z.; Wang, M.; Wang, Y.-F.; Wang, Y.; Ward, R. L.; Warner, J.; Was, M.; Watchi, J.; Weaver, B.; Wei, L.-W.; Weinert, M.; Weinstein, A. J.; Weiss, R.; Wen, L.; Wessel, E. K.; Weßels, P.; Westphal, T.; Wette, K.; Whelan, J. T.; Whiting, B. F.; Whittle, C.; Williams, D.; Williams, R. D.; Williamson, A. R.; Willis, J. L.; Willke, B.; Wimmer, M. H.; Winkler, W.; Wipf, C. C.; Wittel, H.; Woan, G.; Woehler, J.; Wofford, J.; Wong, K. W. K.; Worden, J.; Wright, J. L.; Wu, D. S.; Wu, G.; Yam, W.; Yamamoto, H.; Yancey, C. C.; Yap, M. J.; Yu, Hang; Yu, Haocun; Yvert, M.; ZadroŻny, A.; Zanolin, M.; Zelenova, T.; Zendri, J.-P.; Zevin, M.; Zhang, L.; Zhang, M.; Zhang, T.; Zhang, Y.-H.; Zhao, C.; Zhou, M.; Zhou, Z.; Zhu, S.; Zhu, X. J.; Zucker, M. E.; Zweizig, J.; LIGO Scientific Collaboration; Virgo Collaboration

2017-09-01

We report on an all-sky search for periodic gravitational waves in the frequency band 20-475 Hz and with a frequency time derivative in the range of [-1.0 ,+0.1 ] ×10-8 Hz /s . Such a signal could be produced by a nearby spinning and slightly nonaxisymmetric isolated neutron star in our galaxy. This search uses the data from Advanced LIGO's first observational run, O1. No periodic gravitational wave signals were observed, and upper limits were placed on their strengths. The lowest upper limits on worst-case (linearly polarized) strain amplitude h0 are ˜4 ×10-25 near 170 Hz. For a circularly polarized source (most favorable orientation), the smallest upper limits obtained are ˜1.5 ×10-25. These upper limits refer to all sky locations and the entire range of frequency derivative values. For a population-averaged ensemble of sky locations and stellar orientations, the lowest upper limits obtained for the strain amplitude are ˜2.5 ×10-25.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yadav, Praveen Kumar, E-mail: praveenyadav@rrcat.gov.in; Nayak, Maheswar; Rai, Sanjay Kumar

The authors report the effect of argon ion to molybdenum atom ratio (r) on the microstructure of low energy (70 eV) argon ion assisted electron beam evaporated Mo thin films. Surface roughness, morphology, and crystallinity of Mo films are found to strongly depend on “r.” Increase of “r” from 0 to 100 induces gradual loss in crystallinity, reduction in surface roughness and systematic increase in density of the film. For “r” ∼ 100, average atomic density of the film approaches the bulk value (97%) with lowest surface roughness. Further, increasing “r” up to 170 reduces the atomic density, increases roughness, and increase inmore » crystallinity induced by low energy Ar ion beam. The observed surface roughness and grain size determined by x-ray reflectivity and glancing incidence x-ray diffraction correlate well with atomic force microscopy measurements. This study demonstrates that for r = 100 one gets lowest roughness Mo film with highest density and nearly amorphous microstructure. The growth model is discussed by structural zone model.« less

Is laser conditioning a valid alternative to conventional etching for aesthetic brackets?

PubMed

Sfondrini, M F; Calderoni, G; Vitale, M C; Gandini, P; Scribante, A

2018-03-01

ER:Yag lasers have been described as a more conservative alternative to conventional acid-etching enamel conditioning technique, when bonding conventional metallic orthodontic brackets. Since the use of aesthetic orthodontic brackets is constantly increasing, the purpose of the present report has been to test laser conditioning with different aesthetic brackets. Study Design: Five different aesthetic brackets (microfilled copolymer, glass fiber, sapphire, polyoxymethylene and sintered ceramic) were tested for shear bond strength and Adhesive Remnant Index scores using two different enamel conditioning techniques (acid etching and ER:Yag laser application). Two hundred bovine incisors were extracted, cleaned and embedded in resin. Specimens were then divided into 10 groups with random tables. Half of the specimens were conditioned with conventional orthophosphoric acid gel, the other half with ER:Yag laser. Different aesthetic brackets (microfilled copolymer, glass fiber, sapphire, polyoxymethylene and sintered ceramic) were then bonded to the teeth. Subsequently all groups were tested in shear mode with a Universal Testing Machine. Shear bond strength values and adhesive remnant index scores were recorded. Statistical analysis was performed. When considering conventional acid etching technique, sapphire, polyoxymethylene and sintered ceramic brackets exhibited the highest SBS values. Lowest values were reported for microfilled copolymer and glass fiber appliances. A significant decrease in SBS values after laser conditioning was reported for sapphire, polyoxymethylene and sintered ceramic brackets, whereas no significant difference was reported for microfilled copolymer and glass fiber brackets. Significant differences in ARI scores were also reported. Laser etching can significantly reduce bonding efficacy of sapphire, polyoxymethylene and sintered ceramic brackets.

Nonvascular thoracic magnetic resonance imaging: the current state of training, utilization, and perceived value: survey of the Society of Thoracic Radiology membership.

PubMed

Ackman, Jeanne B; Wu, Carol C; Halpern, Elkan F; Abbott, Gerald F; Shepard, Jo-Anne O

2014-07-01

The aim of the study was to determine the current state of training, utilization, and perceived value of nonvascular thoracic magnetic resonance imaging (MRI). The URL link for this anonymous, IRB-approved survey was e-mailed to all Society of Thoracic Radiology members with available e-mail addresses (733), of whom 693 were qualified to respond as per the survey's instructions. Survey questions focused on MRI training, interpretation volume, perceived value of thoracic MRI, and barriers to its utilization. Study data were collected and managed using Research Electronic Data Capture (REDCap) electronic data capture tools and analyzed with χ tests. The survey response rate was 27% (190/693). Thirty-seven percent (67/180) of respondents reported that they interpreted and reported zero thoracic MRIs and 64% (116/182) interpreted or reported <10 MRIs over the prior year. The perceived value of thoracic MRI was highest for chest wall and neurovascular involvement and evaluation of the mediastinum, particularly thymus, next highest for assessment of pleural or diaphragmatic lesions, and lowest for assessment of lung function with hyperpolarized gases. Seventy-three percent (121/166) of respondents felt it would be of value to increase utilization of thoracic MRI. Perceived obstacles to increasing thoracic MRI utilization included lack of: awareness of referring health care providers as to the value of thoracic MRI (59%, 98/166), radiologist proficiency or comfort with thoracic MRI (46%, 77/166), standardized protocols (38%, 64/166), technologist experience (38%, 63/166), and sufficient training during residency and/or fellowship (32%, 54/166). Twenty-five percent (41/166) of respondents reported insufficient thoracic MRI literature and limited CME courses and lectures in this field as an additional impediment. The majority of survey respondents reported limited experience in thoracic MRI interpretation, a recognition of thoracic MRI's value, and an interest in increasing its utilization. Improved education of radiologists, technologists, and referring clinicians would ameliorate the current state.

TH-CD-202-08: Feasibility Study of Planning Phase Optimization Using Patient Geometry-Driven Information for Better Dose Sparing of Organ at Risks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kang, S; Kim, D; Kim, T

2016-06-15

Purpose: To propose a simple and effective cost value function to search optimal planning phase (gating window) and demonstrated its feasibility for respiratory correlated radiation therapy. Methods: We acquired 4DCT of 10 phases for 10 lung patients who have tumor located near OARs such as esophagus, heart, and spinal cord (i.e., central lung cancer patients). A simplified mathematical optimization function was established by using overlap volume histogram (OVH) between the target and organ at risk (OAR) at each phase and the tolerance dose of selected OARs to achieve surrounding OARs dose-sparing. For all patients and all phases, delineation of themore » target volume and selected OARs (esophagus, heart, and spinal cord) was performed (by one observer to avoid inter-observer variation), then cost values were calculated for all phases. After the breathing phases were ranked according to cost value function, the relationship between score and dose distribution at highest and lowest cost value phases were evaluated by comparing the mean/max dose. Results: A simplified mathematical cost value function showed noticeable difference from phase to phase, implying it is possible to find optimal phases for gating window. The lowest cost value which may result in lower mean/max dose to OARs was distributed at various phases for all patients. The mean doses of the OARs significantly decreased about 10% with statistical significance for all 3 OARs at the phase with the lowest cost value. Also, the max doses of the OARs were decreased about 2∼5% at the phase with the lowest cost value compared to the phase with the highest cost value. Conclusion: It is demonstrated that optimal phases (in dose distribution perspective) for gating window could exist differently through each patient and the proposed cost value function can be a useful tool for determining such phases without performing dose optimization calculations. This research was supported by the Mid-career Researcher Program through NRF funded by the Ministry of Science, ICT & Future Planning of Korea (NRF-2014R1A2A1A10050270) and by the Radiation Technology R&D program through the National Research Foundation of Korea funded by the Ministry of Science, ICT & Future Planning (No. 2013M2A2A7038291)« less

Carbon and nitrogen abundances in metal-poor dwarfs of the solar neighborhood

NASA Technical Reports Server (NTRS)

Carbon, Duane F.; Barbuy, Beatrice; Kraft, Robert P.; Friel, Eileen D.; Suntzeff, Nicholas B.

1987-01-01

Intermediate-resolution C, N, and Fe abundance spectra for 83 subdwarfs in the lowest metallicity range (-1.5 to -3.2), obtained with the Lick Observatory 3.1-m Shane telescope, are analyzed. The effects of subgiants and binaries on the sample are examined. The relation between (B-V) and (V-K) and effective temperature is studied. C/Fe, N/Fe, and Fe/H abundances were determined using the model-atmosphere technique of spectrum synthesis. The derived abundance values are compared with data from previous investigations. It is observed that there is good correlation between the Fe/H abundance values derived from the intermediate-resolution spectra and those based on high-resolution spectra; C/Fe abundance values are constant; and there is an upturn in the C/Fe abundance values at the very lowest metallicities.

Quality Properties of Sausages Made with Replacement of Pork with Corn Starch, Chicken Breast and Surimi during Refrigerated Storage

PubMed Central

2015-01-01

This effect of replacing pork with corn starch, chicken breast and surimi on the chemical composition, physical, texture and sensory properties of sausage were investigated during storage. Five treatments of sausage such as; T1 (10:0:0, %), T2 (10:5:0, %), T3 (10:10:5, %), T4 (10:15:10, %) and T5 (10:20:15, %) were prepared with replacement of pork with corn starch, chicken breast and surimi. The sausage made with pork meat served as control (C). The sausage in the control had higher moisture and fat contents, but lower protein content than the treatments (p<0.05). The sausages in the T2 and T5 had decreased pH values after 3 wk storage (p<0.05). The lightness value was lowest in the T3, while the yellowness values were lowest in the T5 during the storage. The TBARS (2-thiobarbituric acid reactive substance) values were lowest in the control in all storage times (p<0.05). However, the sausage in the control had higher VBN (volatile basic nitrogen) value than the treatments during the 1 wk storage (p<0.05). All treatments had significantly higher hardness, cohesiveness, springiness, gumminess and chewiness values (p<0.05) than the control. The results indicated that corn starch, chicken breast and surimi can used as a pork replacer, that it also improves the physicochemical and texture properties of pork sausages. PMID:26761892

Effects of oxygen and antioxidants on the lipid oxidation and yellow discolouration of film from red tilapia mince.

PubMed

Tongnuanchan, Phakawat; Benjakul, Soottawat; Prodpran, Thummanoon

2012-09-01

Generally, biodegradable films from fish muscle protein become yellow after preparation. This discolouration is more likely associated with lipid oxidation and can be prevented by minimising the oxidation in the films. Thus, the effects of oxygen and antioxidants on lipid oxidation and yellow discolouration of film from red tilapia mince during storage were investigated. Both films prepared at pH 3 and 11, and kept under atmosphere containing 100% N(2) had the lowest TBARS value with the concomitant lowest b* and ΔE* values during storage (P < 0.05), when compared with other films kept in air and a 100% O(2) atmosphere. Films prepared at pH 3 and incorporated with antioxidants (Trolox and catechin) at all levels (100, 200 and 400 mg L(-1) film-forming solution) had the lowest TBARS value, b* and ΔE* values during storage, indicating the retardation of lipid oxidation and yellow discolouration in films. Nevertheless, films prepared at pH 11 had no difference in TBARS values, in comparison with control film, regardless of antioxidant incorporation. Coincidentally, increases in b* and ΔE* values were observed in those films. Lipid oxidation was the main factor inducing yellow discolouration of film exposed to oxygen and the incorporation of antioxidants in film prepared at acidic pH was able to prevent yellow discolouration of resulting film. Copyright © 2012 Society of Chemical Industry.

On the Q-dependence of the lowest-order QED corrections and other properties of the ground 11S-states in the two-electron ions

NASA Astrophysics Data System (ADS)

Frolov, Alexei M.

2015-10-01

Formulas and expectation values which are need to determine the lowest-order QED corrections (∼α3) and corresponding recoil (or finite mass) corrections in the two-electron helium-like ions are presented. Other important properties of the two-electron ions are also determined to high accuracy, including the expectation values of the quasi-singular Vinti operator and < reN-2> and < ree-2> expectation values. Elastic scattering of fast electrons by the two-electron ions in the Born approximation is considered. Interpolation formulas are derived for the bound state properties of the two-electron ions as the function of the nuclear electric charge Q.

Mass Spectra of Ds and Ωc in Lattice QCD with Nf = 2 + 1 + 1 Domain-Wall Quarks

NASA Astrophysics Data System (ADS)

Chiu, Ting-Wai

2018-03-01

We perform hybrid Monte Carlo simulation of lattice QCD with Nf = 2+1+1 optimal domain-wall quarks on the 323 × 64 lattice with lattice spacing a 0:06 fm, and generate a gauge ensemble with physical s and c quarks, and pion mass 280 MeV. Using 2-quark (meson) and 3-quark (baryon) interpolating operators, the mass spectra of the lowest-lying states containing s and c quarks (Ds and Ωc) are extracted [1], which turn out in good agreement with the high energy experimental values, together with the predictions of the charmed baryons which have not been observed in experiments. For the five new narrow c states observed by the LHCb Collaboration [2], the lowest-lying Ωc(3000) agrees with our predicted mass 3015(29)(34) MeV of the lowest-lying Ωc with JP = 1/2-. This implies that JP of Ωc(3000) is 1/2-.

Mexican American 7th Graders’ Future Work and Family Plans: Associations with Cultural Experiences and Adjustment

PubMed Central

Cansler, Emily; Updegraff, Kimberly A.; Simpkins, Sandra D.

2011-01-01

We describe Mexican American 7th graders’ expectations for future work and family roles and investigate links between patterns of future expectations and adolescents’ cultural experiences and adjustment. Adolescents participated in home interviews and a series of seven nightly phone calls. Five unique patterns of adolescents’ future expectations were identified (N = 246): Career Oriented, Independent, Family Oriented, Early, and Inconsistent. Career Oriented adolescents had the highest socioeconomic status and contact with the U.S. (e.g., generation status) whereas Family Oriented adolescents had the lowest. Cultural orientations, values, and involvement also varied across groups. For example, Career Oriented adolescents reported significantly higher familism values compared to Inconsistent adolescents. Clusters also differed on adjustment: Career Oriented and Family Oriented adolescents reported higher parental warmth and less risky behavior compared to Independent and Inconsistent adolescents. Findings underscore the multi-faceted nature of adolescents’ future expectations and the diversity in cultural experiences among Mexican origin youth. PMID:23338812

Latent profile analysis of students' motivation and outcomes in mathematics: an organismic integration theory perspective.

PubMed

Wang, Chee Keng John; Liu, Woon Chia; Nie, Youyan; Chye, Yen Leng Stefanie; Lim, Boon San Coral; Liem, Gregory Arief; Tay, Eng Guan; Hong, Ying-Yi; Chiu, Chi-Yue

2017-05-01

The purpose of the current study was to identify the motivation profiles at the intraindividual level using a latent profile analyses (LPA) approach. A total of 1151 secondary school students aged 13 to 17 years old from Singapore took part in the study. Using LPA, four distinct motivational profiles were identified based on four motivation regulations. Profile 1 has very low introjected and low autonomous motivation (6% of sample). Profile 2 had high external and identified regulations and very low intrinsic regulation (10%). Profile 3 consisted of students with high identified and intrinsic regulations (51%). Profile 4 had moderately low identified and intrinsic regulations (33%). The results showed that the four profiles differed significantly in terms of effort, competence, value, and time spent on math beyond homework. The best profile (Profile 3) reported highest scores in effort, value, competence and time spent on Math beyond homework. The worst profile (Profile 1) reported lowest scores in all the four outcome variables.

Predictive value of autoantibody testing for validating self-reported diagnoses of rheumatoid arthritis in the Women's Health Initiative.

PubMed

Walitt, Brian; Mackey, Rachel; Kuller, Lewis; Deane, Kevin D; Robinson, William; Holers, V Michael; Chang, Yue-Fang; Moreland, Larry

2013-05-01

Rheumatoid arthritis (RA) research using large databases is limited by insufficient case validity. Of 161,808 postmenopausal women in the Women's Health Initiative, 15,691 (10.2%) reported having RA, far higher than the expected 1% population prevalence. Since chart review for confirmation of an RA diagnosis is impractical in large cohort studies, the current study (2009-2011) tested the ability of baseline serum measurements of rheumatoid factor and anti-cyclic citrullinated peptide antibodies, second-generation assay (anti-CCP2), to identify physician-validated RA among the chart-review study participants with self-reported RA (n = 286). Anti-CCP2 positivity had the highest positive predictive value (PPV) (80.0%), and rheumatoid factor positivity the lowest (44.6%). Together, use of disease-modifying antirheumatic drugs and anti-CCP2 positivity increased PPV to 100% but excluded all seronegative cases (approximately 15% of all RA cases). Case definitions inclusive of seronegative cases had PPVs between 59.6% and 63.6%. False-negative results were minimized in these test definitions, as evidenced by negative predictive values of approximately 90%. Serological measurements, particularly measurement of anti-CCP2, improved the test characteristics of RA case definitions in the Women's Health Initiative.

Profiling nurses' job satisfaction, acculturation, work environment, stress, cultural values and coping abilities: A cluster analysis.

PubMed

Goh, Yong-Shian; Lee, Alice; Chan, Sally Wai-Chi; Chan, Moon Fai

2015-08-01

This study aimed to determine whether definable profiles existed in a cohort of nursing staff with regard to demographic characteristics, job satisfaction, acculturation, work environment, stress, cultural values and coping abilities. A survey was conducted in one hospital in Singapore from June to July 2012, and 814 full-time staff nurses completed a self-report questionnaire (89% response rate). Demographic characteristics, job satisfaction, acculturation, work environment, perceived stress, cultural values, ways of coping and intention to leave current workplace were assessed as outcomes. The two-step cluster analysis revealed three clusters. Nurses in cluster 1 (n = 222) had lower acculturation scores than nurses in cluster 3. Cluster 2 (n = 362) was a group of younger nurses who reported higher intention to leave (22.4%), stress level and job dissatisfaction than the other two clusters. Nurses in cluster 3 (n = 230) were mostly Singaporean and reported the lowest intention to leave (13.0%). Resources should be allocated to specifically address the needs of younger nurses and hopefully retain them in the profession. Management should focus their retention strategies on junior nurses and provide a work environment that helps to strengthen their intention to remain in nursing by increasing their job satisfaction. © 2014 Wiley Publishing Asia Pty Ltd.

Juvenile Arrests, 2000. Juvenile Justice Bulletin.

ERIC Educational Resources Information Center

Snyder, Howard N.

This bulletin examines the national and state juvenile arrest rate in 2000 using data reported annually by local law enforcement agencies nationwide to the FBI's Uniform Crime Reporting program. Results indicate that the murder rate in 2000 was the lowest since 1965; juvenile arrests for violence in 2000 were the lowest since 1988; few juveniles…

Ultra low power consumption for self-oscillating nanoelectromechanical systems constructed by contacting two nanowires.

PubMed

Barois, T; Ayari, A; Vincent, P; Perisanu, S; Poncharal, P; Purcell, S T

2013-04-10

We report here the observation of a new self-oscillation mechanism in nanoelectromechanical systems (NEMS). A highly resistive nanowire was positioned to form a point-contact at a chosen vibration node of a silicon carbide nanowire resonator. Spontaneous and robust mechanical oscillations arise when a sufficient DC voltage is applied between the two nanowires. An original model predicting the threshold voltage is used to estimate the piezoresistivity of the point-contact in agreement with the observations. The measured input power is in the pW-range which is the lowest reported value for such systems. The simplicity of the contacting procedure and the low power consumption open a new route for integrable and low-loss self-excited NEMS devices.

Quantitative structure-property relationships for octanol-water partition coefficients of polybrominated diphenyl ethers.

PubMed

Li, Linnan; Xie, Shaodong; Cai, Hao; Bai, Xuetao; Xue, Zhao

2008-08-01

Theoretical molecular descriptors were tested against logK(OW) values for polybrominated diphenyl ethers (PBDEs) using the Partial Least-Squares Regression method which can be used to analyze data with many variables and few observations. A quantitative structure-property relationship (QSPR) model was successfully developed with a high cross-validated value (Q(cum)(2)) of 0.961, indicating a good predictive ability and stability of the model. The predictive power of the QSPR model was further cross-validated. The values of logK(OW) for PBDEs are mainly governed by molecular surface area, energy of the lowest unoccupied molecular orbital and the net atomic charges on the oxygen atom. All these descriptors have been discussed to interpret the partitioning mechanism of PBDE chemicals. The bulk property of the molecules represented by molecular surface area is the leading factor, and K(OW) values increase with the increase of molecular surface area. Higher energy of the lowest unoccupied molecular orbital and higher net atomic charge on the oxygen atom of PBDEs result in smaller K(OW). The energy of the lowest unoccupied molecular orbital and the net atomic charge on PBDEs oxygen also play important roles in affecting the partition of PBDEs between octanol and water by influencing the interactions between PBDEs and solvent molecules.

Water quality of streams tributary to Lakes Superior and Michigan

USGS Publications Warehouse

Zimmerman, Jerome W.

1968-01-01

Water quality of streams tributary to Lakes Superior and Michigan was analyzed for 142 stations on 99 streams tributary to Lake Superior and 83 stations on 56 streams tributary to Lake Michigan during 1962-65. Concentrations of aluminum, copper, and iron were not affected greatly by flow or season. Magnesium, calcium, chlorides, total alkalinity, total hardness, and conductivity varied with the flow, temperature, and season; the lowest values were during the spring runoff and heavy rains, and the highest were during low water in late summer and the colder periods of winter. Concentrations of nitrate, silica, and sulfates were lowest in the spring and summer. Concentrations of tanninlike and ligninlike compounds were highest during the spring runoff and other high-water periods, and were lowest during freezeup when surface runoff was minimal. The pH values were highest from June to September and lowest during the spring runoff. Phenolphthalein alkalinity was detected primarily in the summer and coincided occasionally with low flows just before the spring thaw. Total hardness usually was lower in streams tributary to Lake Superior than in streams tributary to Lake Michigan. The total hardness was higher in the streams in Wisconsin than in the streams in Michigan along the west shore of Lake Michigan. It was lowest in the northernmost streams. The water quality of the streams in an area was related to the geological characteristics of the land.

Acute hypoxia in a simulated high-altitude airdrop scenario due to oxygen system failure.

PubMed

Ottestad, William; Hansen, Tor Are; Pradhan, Gaurav; Stepanek, Jan; Høiseth, Lars Øivind; Kåsin, Jan Ivar

2017-12-01

High-Altitude High Opening (HAHO) is a military operational procedure in which parachute jumps are performed at high altitude requiring supplemental oxygen, putting personnel at risk of acute hypoxia in the event of oxygen equipment failure. This study was initiated by the Norwegian Army to evaluate potential outcomes during failure of oxygen supply, and to explore physiology during acute severe hypobaric hypoxia. A simulated HAHO without supplemental oxygen was carried out in a hypobaric chamber with decompression to 30,000 ft (9,144 m) and then recompression to ground level with a descent rate of 1,000 ft/min (305 m/min). Nine subjects were studied. Repeated arterial blood gas samples were drawn throughout the entire hypoxic exposure. Additionally, pulse oximetry, cerebral oximetry, and hemodynamic variables were monitored. Desaturation evolved rapidly and the arterial oxygen tensions are among the lowest ever reported in volunteers during acute hypoxia. Pa O 2 decreased from baseline 18.4 (17.3-19.1) kPa, 138.0 (133.5-143.3) mmHg, to a minimum value of 3.3 (2.9-3.7) kPa, 24.8 (21.6-27.8) mmHg, after 180 (60-210) s, [median (range)], N = 9. Hyperventilation with ensuing hypocapnia was associated with both increased arterial oxygen saturation and cerebral oximetry values, and potentially improved tolerance to severe hypoxia. One subject had a sharp drop in heart rate and cardiac index and lost consciousness 4 min into the hypoxic exposure. A simulated high-altitude airdrop scenario without supplemental oxygen results in extreme hypoxemia and may result in loss of consciousness in some individuals. NEW & NOTEWORTHY This is the first study to investigate physiology and clinical outcome of oxygen system failure in a simulated HAHO scenario. The acquired knowledge is of great value to make valid risk-benefit analyses during HAHO training or operations. The arterial oxygen tensions reported in this hypobaric chamber study are among the lowest ever reported during acute hypoxia. Copyright © 2017 the American Physiological Society.

Association of δ13C in Fingerstick Blood with Added Sugars and Sugar-sweetened Beverage Intake

PubMed Central

Davy, Brenda M.; Jahren, A. Hope; Hedrick, Valisa E.; Comber, Dana L.

2011-01-01

A reliance on self-reported dietary intake measures is a common research limitation, thus the need for dietary biomarkers. Added sugar intake may play a role in the development and progression of obesity and related co-morbidities; common sweeteners include corn and sugar cane derivatives. These plants contain a high amount of 13C, a naturally-occurring stable carbon isotope. Consumption of these sweeteners, of which sugar-sweetened beverages (SSB) are the primary dietary source, may be reflected in the δ13C value of blood. Fingerstick blood represents an ideal substrate for bioassay due to its ease of acquisition. The objective of this investigation was to determine if the δ13C value of fingerstick blood is a potential biomarker of added sugar and SSB intake. Individuals aged ≥21 years (n=60) were recruited to attend three laboratory visits; assessments completed at each visit depended upon a randomly assigned sequence (sequence one or two). The initial visit included assessment of height, weight, and dietary intake (sequence one: beverage intake questionnaire [BEVQ], sequence two: four-day food intake record [FIR]). Sequence one participants completed an FIR at visit two, and non-fasting blood samples were obtained via routine finger sticks at visits one and three. Sequence two participants completed a BEVQ at visit two, and provided fingerstick blood samples at visits two and three. Samples were analyzed for δ13C value using natural abundance stable isotope mass spectrometry. δ13C value was compared to dietary outcomes in all participants, as well as among those in the highest and lowest tertile of added sugar intake. Reported mean added sugar consumption was 66±5g/day, and SSB consumption was 330±53g/day and 134±25 kcal/day. Mean fingerstick δ13C value was −19.94±0.10‰, which differed by BMI status. δ13C value was associated (all p<0.05) with intake of total added sugars (g, r=0.37; kcal, r=0.37), soft drinks (g, r=0.26; kcal, r=0.27), and total SSB (g, r=0.28; kcal, r=0.35). The δ13C value in the lowest and the highest added sugar intake tertiles were significantly different (mean difference = −0.48‰, p=0.028). Even though there are several potential dietary sources for blood carbon, the δ13C value of fingerstick blood shows promise as a non-invasive biomarker of added sugar and SSB intake based on these findings. PMID:21616200

Analysis of interspecies physicochemical variation of grain legume seeds

NASA Astrophysics Data System (ADS)

Rybiński, Wojciech; Rusinek, Robert; Szot, Bogusław; Bocianowski, Jan; Starzycki, Michał

2014-10-01

The paper presents an attempt to assess the reaction of seeds to mechanical loads taking into account their geometry expressed as seed thickness and 1000 seed weight. The initial material comprised 33 genotypes of grain legume plants and included cultivars registered in the country and breeding lines that are subject to pre-registration trials. The analysis of variance revealed significant diversity of the cultivars and lines of the species studied in terms of each of the analysed trait. The highest weight of 1000 seeds were obtained for white lupine seeds and peas, the lowest for andean lupine seeds. The maximum deformation and energy were obtained for white lupine seeds, the lowest for pea seeds, the maximum force and module the lowest values were determined for narrow-leafed lupine and pea. The highest values of protein were obtained for andean and yellow lupine, a fat content for andean and white lupine. The fatty acid profile as much as 70% or more were linoleic and oleic acids. Against the background of all the species are distinguished by white lupine seeds with a high content of oleic acid and the lowest of linoleic acid, for yellow lupine were obtained the inverse ratio of the two acids.

Physicochemical properties and digestibility of common bean (Phaseolus vulgaris L.) starches.

PubMed

Du, Shuang-Kui; Jiang, Hongxin; Ai, Yongfeng; Jane, Jay-Lin

2014-08-08

Physicochemical properties and digestibility of pinto bean, red kidney bean, black bean and navy bean starches were analyzed. All the common bean starches had oval and spherical granules with average diameter of 25.3-27.4 μm. Amylose contents were 32.0-45.4%. Black bean starch showed the highest peak viscosity, breakdown, final viscosity and setback, whereas red kidney bean starch showed the lowest pasting temperature, peak viscosity, breakdown, and setback. Pinto bean starch showed the highest onset and peak gelatinization temperatures, and the lowest gelatinization temperature range; whereas navy bean starch exhibited the lowest values. Amylopectin of red kidney bean had the highest molecular weight (Mw) and z-average gyration radius (Rz), whereas black bean amylopectin had the lowest values of Mw and Rz. The proportions of DP 6-12, DP 13-24, DP 25-36, and DP ≥ 37 and average branch-chain lengths were 23.30-35.21%, 47.79-53.53%, 8.99-12.65%, 6.39-13.49%, and 17.91-21.56, respectively. All the native bean starches were highly resistant to enzyme digestion. Copyright © 2014 Elsevier Ltd. All rights reserved.

Accuracy of HIV-related risk behaviors reported by female sex workers, Iran: a method to quantify measurement bias in marginalized populations.

PubMed

Mirzazadeh, Ali; Haghdoost, Ali Akbar; Nedjat, Saharnaz; Navadeh, Soodabeh; McFarland, Willi; Mohammad, Kazem

2013-02-01

We quantified discrepancies in reported behaviors of female sex workers (FSW) by comparing 63 face-to-face interviews (FTFI) to in-depth interviews (IDI), with corroboration of the directions and magnitudes of reporting by a panel of psychologists who work with FSW. Sensitivities, specificities, positive and negative predictive values (PPV and NPV) were assessed for FTFI responses using IDI as a "gold standard". Sensitivities were lowest in reporting symptoms of sexually transmitted infections (63.9 %), finding sex partners in venues (52.4 %) and not receiving HIV test results (66.7 %). Specificities (all >83 %) and PPVs (all >74.0 %) were higher than NPV. FSW significantly under-reported number of clients, sexual contacts and non-condom use sex acts with clients and number of days engaging in sex work in the preceding week. This study provides a quantified gauge of reporting biases in FSW behaviors. Such estimates and methods help better understand true HIV risk in marginalized populations and calibrate survey estimates accordingly.

Implant-Supported Fixed Partial Prostheses With Different Prosthetic Materials: A Three-Dimensional Finite Element Stress Analysis.

PubMed

Arinc, Hakan

2018-06-01

To evaluate the effects of prosthetic material on the degree of stress to the cortical bone, trabecular bone, framework, and implants using finite element analysis (FEA). A mandibular implant-supported fixed prosthesis was designed. Different prosthetic materials [cobalt-chromium-supported ceramic, zirconia-supported ceramic, and zirconia-reinforced polymethyl methacrylate (ZRPMMA)-supported resin] were used. FEA was used to evaluate stress under different loading conditions. Maximum principal (σmax), minimum principal (σmin), and von Mises (σvM) stress values were obtained. Similar σmax, σmin, and σvM values were observed in the cortical and trabecular bones and in implants under both loading conditions, with the exception of the ZRPMMA model, which showed the highest σmax, σmin, and σvM values in oblique loading. The ZRPMMA model had the lowest σvM value in the framework under both loading conditions. ZRPMMA had the lowest stress values in the framework, with increased stress values in the implants and bone tissue. Framework and veneering materials may influence stress values under different loading conditions.

Radical scavenging activity of selected medicinal plants from Limpopo province of South Africa.

PubMed

Chauke, A M; Shai, L J; Mphahlele, P M; Mogale, M A

2012-01-01

Plants collected from Limpopo province of South Africa were investigated for their antioxidative potential using the DPPH radical scavenging assay. Acetone extracts of Flueggea virosa had the highest antioxidant activity with an IC₅₀ value of 30 µg/ml, closely matching the ascorbic acid with an IC₅₀ value of 25 µg/ml. The lowest antioxidant readings were observed with extracts of Rhynchosia venulosa (root extract) and Ficus ingens (leaf extract). Acetone extract of Bridelia virosa leaves had the highest phenolic content (156 mg GAE/g extract), while the lowest content was recorded for R. venulosa root extract and leaf extract of F. ingens (8.3 and 17.7 mg GAE/g extract, respectively). There was a linear correlation between antioxidant activity and total phenolic content. Extracts with high phenolic content had low IC₅₀ values, while extracts with low phenolic concentrations had high IC₅₀ values.

Lowest Energy Electronic States of Rare Earth Monoxides.

DTIC Science & Technology

1980-09-01

CCSSON No. 3. RECtPIENT-S CATALOG NUMBER fLowest Energy Electronic States of Rare)J 1’Final $ cientific -, S. PERFORMING OR. REPORT NUMBER 7. ATHOR...Cambridge, Massachusetts 02139 Final Report 1 January 1977 - 15 August 1980 1 September 1980 Approved for public release; distribution unlimited AIR...IUncl ass i fie d SECUA.ITY CLASSIFICATION OF THIS PAGE rWhen Data Entered) READ INSTRUCTIONS ,j REPORT DOCUMENTATION PAGE BEFtORE COMPLETING FORM 2.GOT

Industry Financial Relationships in Orthopaedic Surgery: Analysis of the Sunshine Act Open Payments Database and Comparison with Other Surgical Subspecialties.

PubMed

Cvetanovich, Gregory L; Chalmers, Peter N; Bach, Bernard R

2015-08-05

Industry financial relationships for orthopaedic surgeons in the United States are now publicly reported in the Sunshine Act Open Payments database. We sought to present these data in a more easily understandable format and to describe how industry relationships in orthopaedic surgery compare with other surgical subspecialties. The Open Payments database was searched for all records of industry financial relationships for orthopaedic surgeons. Data analyzed included the value of reported financial relationships per surgeon, the type of financial relationship, and geographic region. Similar analytics were collected for neurological surgery, urology, plastic surgery, and otolaryngology. Data were normalized to the overall number of providers in each subspecialty in the United States from the American Medical Association 2012 data. For 12,320 orthopaedic surgeons, 58,127 industry financial relationships were reported, with a total value of $80.2 million. Royalties or licensing fees, which were received by 1.7% of U.S. orthopaedic surgeons, accounted for 69.5% of the total monetary value of payments to orthopaedic surgeons. Between August and December 2013, 50.1% of U.S. orthopaedic surgeons had a reported financial relationship. Orthopaedics had the second lowest percentage of physicians with industry financial relationships among the five surgical subspecialties studied. The overall value of payments per orthopaedic surgeon was higher than in the other subspecialties, driven by the large value of royalties and licensing. One-half of U.S. orthopaedic surgeons have industry financial relationships reported in the Open Payments database. Orthopaedic surgeons are less likely than most surgical subspecialists to receive industry payments, and the majority of the overall value of orthopaedic financial relationships is driven by a small number of orthopaedic surgeons receiving royalties and licensing for reimbursable innovation within the field. Copyright © 2015 by The Journal of Bone and Joint Surgery, Incorporated.

Species sensitivity distribution evaluation for selenium in fish eggs: considerations for development of a Canadian tissue-based guideline.

PubMed

DeForest, David K; Gilron, Guy; Armstrong, Sarah A; Robertson, Erin L

2012-01-01

A freshwater Se guideline was developed for consideration based on concentrations in fish eggs or ovaries, with a focus on Canadian species, following the Canadian Council of Ministers of the Environment protocol for developing guideline values. When sufficient toxicity data are available, the protocol recommends deriving guidelines as the 5th percentile of the species sensitivity distribution (SSD). When toxicity data are limited, the protocol recommends a lowest value approach, where the lowest toxicity threshold is divided by a safety factor (e.g., 10). On the basis of a comprehensive review of the current literature and an assessment of the data therein, there are sufficient egg and ovary Se data available for freshwater fish to develop an SSD. For most fish species, Se EC10 values (10% effect concentrations) could be derived, but for some species, only no-observed-effect concentrations and/or lowest-observed-effect concentrations could be identified. The 5th percentile egg and ovary Se concentrations from the SSD were consistently 20 µg/g dry weight (dw) for the best-fitting distributions. In contrast, the lowest value approach using a safety factor of 10 would result in a Se egg and ovary guideline of 2 µg/g dw, which is unrealistically conservative, as this falls within the range of egg and ovary Se concentrations in laboratory control fish and fish collected from reference sites. An egg and ovary Se guideline of 20 µg/g dw should be considered a conservative, broadly applicable guideline, as no species mean toxicity thresholds lower than this value have been identified to date. When concentrations exceed this guideline, site-specific studies with local fish species, conducted using a risk-based approach, may result in higher egg and ovary Se toxicity thresholds. Copyright © 2011 SETAC.

A dose-finding, cross-over study to evaluate the effect of a Nestorone®/Estradiol transdermal gel delivery on ovulation suppression in normal ovulating women.

PubMed

Brache, Vivian; Merkatz, Ruth; Kumar, Narender; Jesam, Cristian; Sussman, Heather; Hoskin, Elena; Roberts, Kevin; Alami, Mohcine; Taylor, Deshawn; Jorge, Aidelis; Croxatto, Horacio; Lorange, Ellen; Mishell, Daniel R; Sitruk-Ware, Regine

2015-10-01

This study aims to determine the lowest effective of three Nestorone (NES)/estradiol (E2) transdermal gel doses to ensure ovulation suppression in 90-95% of cycles. This was a randomized, open-label, three-treatment-period cross-over study to evaluate the effects of NES/E2 transdermal gel on ovulation inhibition, suppression of follicular growth and pharmacokinetic parameters. The doses were low (1.5 mg NES/0.5 mg E2), medium (3.0 mg NES/1.0 mg E2) and high (4.5 mg NES/1.5 mg E2). Participants applied gel daily to a fixed area on the abdomen for 21 consecutive days. They were interviewed regarding their experiences using the gel. Eighteen participants were randomized; 16 completed the study. Median NES C(max) values for low, medium and high dose groups at day 21 were 318.6 pmol/L, 783.0 pmol/L and 1063.8 pmol/L, respectively. Median maximum follicular diameter was higher with the lowest dose with 16.2 mm versus 10.0 and 10.4 mm with the medium and high doses, respectively. Among adherent participants, ovulation was inhibited in all dose groups, except for one participant in the medium dose (6.7%) that had luteal activity and an ultrasound image suggestive of a luteinized unruptured follicle. There were few reports of unscheduled bleeding, with more episodes reported for the lower dose. Adverse events were mild, and no skin irritation was reported from gel application. While all three doses blocked ovulation effectively and were evaluated as safe and acceptable, the medium dose was considered the lowest effective dose based on a more adequate suppression of follicular development. Further development of this novel contraceptive delivering NES and E2 is warranted and has potential for improved safety compared to ethinyl-estradiol-based methods. Copyright © 2015 Elsevier Inc. All rights reserved.

Determination of mercury in SRM crude oils and refined products by isotope dilution cold vapor ICP-MS using closed-system combustion.

PubMed

Kelly, W Robert; Long, Stephen E; Mann, Jacqueline L

2003-07-01

Mercury was determined by isotope dilution cold-vapor inductively coupled plasma mass spectrometry (ID-CV-ICP-MS) in four different liquid petroleum SRMs. Samples of approximately 0.3 g were spiked with stable (201)Hg and wet ashed in a closed system (Carius tube) using 6 g of high-purity nitric acid. Three different types of commercial oils were measured: two Texas crude oils, SRM 2721 (41.7+/-5.7 pg g(-1)) and SRM 2722 (129+/-13 pg g(-1)), a low-sulfur diesel fuel, SRM 2724b (34+/-26 pg g(-1)), and a low-sulfur residual fuel oil, SRM 1619b (3.5+/-0.74 ng g(-1)) (mean value and 95% CI). The Hg values for the crude oils and the diesel fuel are the lowest values ever reported for these matrices. The method detection limit, which is ultimately limited by method blank uncertainty, is approximately 10 pg g(-1) for a 0.3 g sample. Accurate Hg measurements in petroleum products are needed to assess the contribution to the global Hg cycle and may be needed in the near future to comply with reporting regulations for toxic elements.

In vitro activity of echinocandins against 562 clinical yeast isolates from a Romanian multicentre study.

PubMed

Mares, Mihai; Minea, Bogdan; Nastasa, Valentin; Rosca, Irina; Bostanaru, Andra-Cristina; Marincu, Iosif; Toma, Vasilica; Cristea, Violeta Corina; Murariu, Carmen; Pinteala, Mariana

2018-06-01

The study presents the echinocandin susceptibility profile of a multi-centre collection of pathogenic yeast isolates from Romanian tertiary hospitals. The 562 isolates were identified using ID32C strips, MALDI-TOF MS and DNA sequencing. Minimal inhibitory concentrations (MICs) of caspofungin (CAS), micafungin (MCA), and anidulafungin (ANI) were assessed and interpreted according to EUCAST guidelines. Minimal fungicidal concentrations (MFC) were determined by plating content from the clear MIC wells. The activity was considered fungicidal at MFC/MIC ≤ 4. The three echinocandins had strongly correlated MICs and high percentages of MIC essential agreement. Most often, MCA had the lowest MICs, followed by CAS and ANI. Against C. parapsilosis and C. kefyr, CAS had the lowest MIC values. The MIC50 values were between 0.03 and 0.25 mg/l, except C. parapsilosis. The MIC90 values were usually one dilution higher. MFCs and MICs were weakly correlated. ANI and MCA had the lowest MFC values. The MFC50 values were between 0.06 and 0.5 mg/l, except C. parapsilosis, C. guilliermondii, and C. dubliniensis. The MFC90 values were usually two dilutions higher. Based on EUCAST breakpoints, 47 isolates (8.4%) were resistant to at least one echinocandin, most often ANI. Most resistant isolates were of C. albicans, C. glabrata, and C. krusei. There were 17 isolates (3%) resistant to echinocandins and fluconazole and most belonged to the same three species. MCA and ANI had the highest rates of fungicidal activity. The high rates of echinocandin resistance and significant multidrug resistance make prophylaxis and empiric therapy difficult.

North Atlantic Basin Tropical Cyclone Activity in Relation to Temperature and Decadal- Length Oscillation Patterns

NASA Technical Reports Server (NTRS)

Wilson, Robert M.

2009-01-01

Yearly frequencies of North Atlantic basin tropical cyclones, their locations of origin, peak wind speeds, average peak wind speeds, lowest pressures, and average lowest pressures for the interval 1950-2008 are examined. The effects of El Nino and La Nina on the tropical cyclone parametric values are investigated. Yearly and 10-year moving average (10-yma) values of tropical cyclone parameters are compared against those of temperature and decadal-length oscillation, employing both linear and bi-variate analysis, and first differences in the 10-yma are determined. Discussion of the 2009 North Atlantic basin hurricane season, updating earlier results, is given.

No hospital left behind? Education policy lessons for value-based payment in healthcare.

PubMed

Maurer, Kristin A; Ryan, Andrew M

2016-01-01

Value-based payment systems have been widely implemented in healthcare in an effort to improve the quality of care. However, these programs have not broadly improved quality, and some evidence suggests that they may increase inequities in care. No Child Left Behind is a parallel effort in education to address uneven achievement and inequalities. Yet, by penalizing the lowest performers, No Child Left Behind's approach to accountability has led to a number of unintended consequences. This article draws lessons from education policy, arguing that financial incentives should be designed to support the lowest performers to improve quality. © 2015 Society of Hospital Medicine.

Discrepancies in describing pain: is there agreement between numeric rating scale scores and pain reduction percentage reported by patients with musculoskeletal pain after corticosteroid injection?

PubMed

Cushman, Daniel; McCormick, Zachary; Casey, Ellen; Plastaras, Christopher T

2015-05-01

Pain intensity is commonly rated on an 11-point Numerical Pain Rating Scale which can be expressed as a calculated percentage pain reduction (CPPR), or by patient-reported percentage pain reduction (PRPPR). We aimed to determine the agreement between CPPR and PRPPR in quantifying musculoskeletal pain improvement at short-term follow-up after a corticosteroid injection. Retrospective cohort study. Urban, academic, physical medicine, and rehabilitation outpatient interventional musculoskeletal and spine center. The agreement between CPPR and PRPPR was determined by concordance correlation coefficient (CCC) in subjects who had experienced improvement in musculoskeletal or radicular pain 3 weeks after a first-time injection at our clinic. Subjects who experienced unchanged pain (PRPPR = 0) were compared to CPPR with paired t-test. We examined 197 subjects with greater than 3/10 pain who underwent first-time fluoroscopic-guided corticosteroid injections. Ninety-three subjects reported higher PRPPR than CPPR values, and 41 subjects reported higher CPPR values. The CCC between CPPR and PRPPR was 0.44 (95% CI 0.35-0.54), with a precision of 0.54 and an accuracy of 0.81, and 95% limits of agreement ranging between -41% and +73%. Values for CCC, precision, and accuracy were higher for males compared to females and were highest in the youngest age group (18-40) and lowest in the middle age group (41-60). PRPPR may not agree with CPPR at 3 week follow-up, as these individuals tend to report a higher estimated percentage improvement compared to the value calculated from their pain scores. Wiley Periodicals, Inc.

Nuclear-spin optical rotation in xenon

DOE Office of Scientific and Technical Information (OSTI.GOV)

Savukov, Igor Mykhaylovich

We report that the nuclear-spin optical rotation (NSOR) effect, which has potential applications in correlated nuclear-spin-resonance optical spectroscopy, has previously been explored experimentally and theoretically in liquid Xe. Calculations of the Xe NSOR constant are very challenging because the result is sensitive to correlations, relativistic effects, and the choice of basis, with strong cancellation between contributions from lowest and remaining states. The relativistic configuration-interaction many-body-theory approach, presented here, is promising because this approach has been successful in predicting various properties of noble-gas atoms, such as energies, oscillator strengths (OSs), Verdet constants, and photoionization cross sections. However, correlations become stronger alongmore » the sequence of noble-gas atoms and the theoretical accuracy in Xe is not as high as, for example, in neon and argon. To improve the accuracy of the Xe Verdet and NSOR constants, which are calculated as explicit sums over the excited states, theoretical values for the several lowest levels are replaced with empirical values of energies, OSs, and hyperfine structure constants. We found that the Xe Verdet constant is in excellent agreement with accurate measurements. To take into account liquid effects, empirical data for energy shifts were also used to correct the NSOR constant. In conclusion, the resulting Xe NSOR constant is in a good agreement with experiment, although the liquid-state effect is treated quite approximately.« less

Nuclear-spin optical rotation in xenon

DOE PAGES

Savukov, Igor Mykhaylovich

2015-10-29

We report that the nuclear-spin optical rotation (NSOR) effect, which has potential applications in correlated nuclear-spin-resonance optical spectroscopy, has previously been explored experimentally and theoretically in liquid Xe. Calculations of the Xe NSOR constant are very challenging because the result is sensitive to correlations, relativistic effects, and the choice of basis, with strong cancellation between contributions from lowest and remaining states. The relativistic configuration-interaction many-body-theory approach, presented here, is promising because this approach has been successful in predicting various properties of noble-gas atoms, such as energies, oscillator strengths (OSs), Verdet constants, and photoionization cross sections. However, correlations become stronger alongmore » the sequence of noble-gas atoms and the theoretical accuracy in Xe is not as high as, for example, in neon and argon. To improve the accuracy of the Xe Verdet and NSOR constants, which are calculated as explicit sums over the excited states, theoretical values for the several lowest levels are replaced with empirical values of energies, OSs, and hyperfine structure constants. We found that the Xe Verdet constant is in excellent agreement with accurate measurements. To take into account liquid effects, empirical data for energy shifts were also used to correct the NSOR constant. In conclusion, the resulting Xe NSOR constant is in a good agreement with experiment, although the liquid-state effect is treated quite approximately.« less

Canaveral National Seashore Water Quality and Aquatic Resource Inventory

NASA Technical Reports Server (NTRS)

Hall, C. R.; Provancha, J. A.; Oddy, D. M.; Lowers, R. L.; Drese, J. D.

2001-01-01

Mosquito Lagoon is a shallow, bar-built estuary located on the east central Florida Coast, primarily within the KSC boundary. The lagoon and watershed cover approximately 327 sq km (79422 acres) .The Lagoon occupies 159 sq km (37853 acres). Water depths average approximately 1m. The lagoon volume is approximately 1.6 x 10(exp 8)cu m. Water quality in Mosquito Lagoon is good. Salinity data typically range between 20 ppt and 35 ppt. The lowest value recorded was 4.5 ppt and the highest value was 37 ppt. Water temperatures fluctuate 2 - 3 C over a 24 h period. Cold front passage can rapidly alter water temperatures by 5 - 10 C or more in a short period of time. The highest temperature was 33.4 C and the lowest temperature was 8.8 C after a winter storm. Dissolved oxygen concentrations ranged from a low of 0.4 mg/l to a high of 15.3 mg/l. Extended periods of measurements below the Florida Department of Environmental Protection criteria of 4.0 mg/l were observed in fall and spring months suggesting high system respiration and oxygen demand. Metals such as antimony, arsenic, molybdenum and mercury were report as below detection limits for all samples. Cadmium, copper, chromium, silver, and zinc were found to be periodically above the Florida Department of Environmental Protection criteria for Class II and Class III surface waters.

Combining hydrogen evolution and corrosion data - A case study on the economic viability of selected metal cathodes in microbial electrolysis cells

NASA Astrophysics Data System (ADS)

Brown, Robert Keith; Schmidt, Ulrike Christiane; Harnisch, Falk; Schröder, Uwe

2017-07-01

In this study, hydrogen evolution reaction (HER) catalytic and corrosion data is determined for selected metal cathode materials. The HER data was gathered using cyclic voltammetry (CV) in electrolytes with several pH values and varying current densities. Of the tested materials, the stainless steel alloy EN 1.4401/AISI 316 generally had the lowest HER overpotentials at the pH values 0.25, 7 and 9. At the higher pH values of 11 and 14 a custom NiMoFe alloy with a m/m% composition of 60-30-10 showed the lowest overpotentials. After each CV experiment, the electrolyte solution was analyzed to determine the corrosion of the metal cathodes. Results of corrosion measurements showed that the stainless steels EN 1.4401 had the lowest corrosion losses on average across all tested pH values. Combining HER and corrosion data revealed that: In the pH 9 electrolyte solution, EN 1.4401 was not always the best catalyst in terms of its overpotential, but it incurs the least material costs due to its lack of corrosion, this balance thereby making it the "best choice" under the given conditions. The combination of HER and corrosion data provides a more effective framework for discussing economic viability than either data set alone.

Revalidation of the isobaric multiplet mass equation for the A = 20 quintet

DOE PAGES

Glassman, B. E.; Pérez-Loureiro, D.; Wrede, C.; ...

2015-10-29

An unexpected breakdown of the isobaric multiplet mass equation in the A = 20, T = 2 quintet was recently reported, presenting a challenge to modern theories of nuclear structure. In the present work, the excitation energy of the lowest T = 2 state in Na-20 has been measured to be 6498.4 +/- 0.2 stat ± 0.4 syst keV by using the superallowed 0 + → 0 + beta decay of Mg-20 to access it and an array of high-purity germanium detectors to detect its gamma-ray deexcitation. This value differs by 27 keV (1.9 standard deviations) from the recommended valuemore » of 6525 ± 14 keV and is a factor of 28 more precise. The isobaric multiplet mass equation is shown to be revalidated when the new value is adopted.« less

Blister formation at subcritical doses in tungsten irradiated by MeV protons

NASA Astrophysics Data System (ADS)

Gavish Segev, I.; Yahel, E.; Silverman, I.; Makov, G.

2017-12-01

The material response of tungsten to irradiation by MeV protons has been studied experimentally, in particular with respect to bubble and blister formation. Tungsten samples were irradiated by 2.2 MeV protons at the Soreq Applied Research Accelerator Facility (SARAF) to doses of the order of 1017 protons/cm2 which are below the reported critical threshold for blister formation derived from keV range irradiation studies. Large, well-developed blisters are observed indicating that for MeV range protons the critical threshold is at least an order of magnitude lower than the lowest value reported previously. The effects of fluence, flux, and corresponding temperature on the distribution and characteristics of the obtained blisters were studied. FIB cross sections of several blisters exposed their depth and structure.

Metabolic flexibility: the key to long-term evolutionary success in Bryozoa?

PubMed

Peck, Lloyd S; Barnes, David K A

2004-02-07

Oxygen consumption (MO2) and activity were evaluated in Antarctic Bryozoa. Three species representing two different morphologies, flat sheet, laminar forms, Isoseculiflustra tenuis and Kymella polaris, and the bush form Camptoplites bicornis were used. In Bryozoa, activity is measured as the proportion of colony zooids with their lophophores extended. In I. tenuis and K. polaris, residual analysis showed that the percentage of zooids with extended lophophores was not correlated with colony MO2. Lophophore extension is, therefore, a poor measure of activity, and other costs (e.g. growth, reproduction, storage) probably form the major metabolic costs. MO2 per unit of ash-free dry mass (AFDM) in the laminar forms was low compared with other Antarctic marine invertebrates, but not lower than brachiopods and echinoderms. However, the lowest rate here, 16.8 microg O2 g AFDM(-1) h(-1) for a K. polaris colony, is (to our knowledge) the lowest for any animal so far reported. MO2 per unit of AFDM for C. bicornis, however, is among the highest reported for sessile or slow moving Antarctic marine ectotherms, with values similar to those for bivalve and gastropod molluscs. The highest rate, 527 microg O2 g AFDM(-1) h(-1) for one colony is (to our knowledge) the highest reported for polar animals of this type. Extreme diversity in metabolic strategy may explain the bryozoan long evolutionary record and great success in shallow marine environments worldwide.

A study of the stress wave factor technique for the characterization of composite materials

NASA Technical Reports Server (NTRS)

Henneke, E. G., II; Duke, J. C., Jr.; Stinchcomb, W. W.; Govada, A.; Lemascon, A.

1983-01-01

A testing program was undertaken to provide an independent investigation and evaluation of the stress wave factor for characterizing the mechanical behavior of composite laminates. Some of the data which was obtained after performing a very large number of tests to determine the reproducibility of the SWF measurement is presented. It was determined that, with some optimizing of experimental parameters, the SWF value can be reproduced to within + or - 10%. Results are also given which show that, after careful calibration procedures, the lowest SWF value along the length of a specimen will correlate very closely to the site of final failure when the specimen is loaded in tension. Finally, using a moire interferometry technique, it was found that local regions having the highest in plane strains under tensile loading also had the lowest SWF values.

Three approaches to define desired soil organic matter contents.

PubMed

Sparling, G; Parfitt, R L; Hewitt, A E; Schipper, L A

2003-01-01

Soil organic C is often suggested as an indicator of soil quality, but desirable targets are rarely specified. We tested three approaches to define maximum and lowest desirable soil C contents for four New Zealand soil orders. Approach 1 used the New Zealand National Soils Database (NSD). The maximum C content was defined as the median value of long-term pastures, and the lower quartile defined the lowest desirable soil C content. Approach 2 used the CENTURY model to predict maximum C contents of long-term pasture. Lowest desirable content was defined by the level that still allowed recovery to 80% of the maximum C content over 25 yr. Approach 3 used an expert panel to define desirable C contents based on production and environmental criteria. Median C contents (0-20 cm) for the Recent, Granular, Melanic, and Allophanic orders were 72, 88, 98, 132 Mg ha(-1), and similar to contents predicted by the CENTURY model (78, 93, 102, and 134 Mg ha(-1), respectively). Lower quartile values (54, 78, 73, and 103 Mg ha(-1), respectively) were similar to the lowest desirable C contents calculated by CENTURY (55, 54, 67, and 104 Mg ha(-1), respectively). Expert opinion was that C contents could be depleted below these values with tolerable effects on production but less so for the environment. The CENTURY model is our preferred approach for setting soil organic C targets, but the model needs calibrating for other soils and land uses. The statistical and expert opinion approaches are less defensible in setting lower limits for desirable C contents.

Self-reported hepatitis A vaccination as a predictor of hepatitis A virus antibody protection in U.S. adults: National Health and Nutrition Examination Survey 2007–2012

PubMed Central

Denniston, Maxine M.; Klevens, R. Monina; Jiles, Ruth B.; Murphy, Trudy V.

2015-01-01

Objectives To estimate the predictive value of self-reported hepatitis A vaccine (HepA) receipt for the presence of hepatitis A virus (HAV) antibody (anti-HAV) from either past infection or vaccination, as an indicator of HAV protection. Methods Using 2007–2012 National Health and Nutrition Examination Survey data, we assigned participants to 4 groups based on self-reported HepA receipt and anti-HAV results. We compared characteristics across groups and calculated three measures of agreement between self-report and serologic status (anti- HAV): percentage concordance, and positive (PPV) and negative (NPV) predictive values. Using logistic regression we investigated factors associated with agreement between self-reported vaccination status and serological results. Results Demographic and other characteristics varied significantly across the 4 groups. Overall agreement between self-reported HepA receipt and serological results was 63.6% (95% confidence interval [CI] 61.9–65.2); PPV and NPV of self-reported vaccination status for serological result were 47.0% (95% CI 44.2–49.8) and 69.4% (95% CI 67.0–71.8), respectively. Mexican American and foreign-born adults had the highest PPVs (71.5% [95% CI 65.9–76.5], and 75.8% [95% CI 71.4–79.7]) and the lowest NPVs (21.8% [95% CI 18.5–25.4], and 20.0% [95% CI 17.2–23.1]), respectively. Young (ages 20–29 years), US-born, and non-Hispanic White adults had the lowest PPVs (37.9% [95% CI 34.5–41.5], 39.1% [95% CI, 36.0–42.3], and 39.8% [36.1–43.7]), and the highest NPVs (76.9% [95% CI 72.2–81.0, 78.5% [95% CI 76.5–80.4)], and 80.6% [95% CI 78.2–82.8), respectively. Multivariate logistic analyses found age, race/ethnicity, education, place of birth and income to be significantly associated with agreement between self-reported vaccination status and serological results. Conclusions When assessing hepatitis A protection, self-report of not having received HepA was most likely to identify persons at risk for hepatitis A infection (no anti-HAV) among young, US-born and non-Hispanic White adults, and self-report of HepA receipt was least likely to be reliable among adults with the same characteristics. PMID:26116252

Effects of seawater acidification on early development of the intertidal sea urchin Paracentrotus lividus (Lamarck 1816).

PubMed

Moulin, Laure; Catarino, Ana Isabel; Claessens, Thomas; Dubois, Philippe

2011-01-01

The effect of pH ranging from 8.0 to 6.8 (total scale - pH(T)) on fertilization, cleavage and larval development until pluteus stage was assessed in an intertidal temperate sea urchin. Gametes were obtained from adults collected in two contrasting tide pools, one showing a significant nocturnal pH decrease (lowest pH(T)=7.4) and another where pH was more stable (lowest pH(T)=7.8). The highest pH(T) at which significant effects on fertilization and cleavage were recorded was 7.6. On the contrary, larval development was only affected below pH(T) 7.4, a value equal or lower than that reported for several subtidal species. This suggests that sea urchins inhabiting stressful intertidal environments produce offspring that may better resist future ocean acidification. Moreover, at pH(T) 7.4, the fertilization rate of gametes whose progenitors came from the tide pool with higher pH decrease was significantly higher, indicating a possible acclimatization or adaptation of gametes to pH stress. Copyright © 2010 Elsevier Ltd. All rights reserved.

A tool for assessing the quality of nursing handovers: a validation study.

PubMed

Ferrara, Paolo; Terzoni, Stefano; Davì, Salvatore; Bisesti, Alberto; Destrebecq, Anne

2017-08-10

Handover, in particular between two shifts, is a crucial aspect of nursing for patient safety, aimed at ensuring continuity of care. During this process, several factors can affect quality of care and cause errors. This study aimed to assess quality of handovers, by validating the Handoff CEX-Italian scale. The scale was translated from English into Italian and the content validity index was calculated and internal consistency assessed. The scale was used in several units of the San Paolo Teaching Hospital in Milan, Italy. A total of 48 reports were assessed (192 evaluations). The median score was 6, interquartile range (IQR) [5;7] and was not influenced by specific (p=0.21) or overall working experience (p=0.13). The domains showing the lowest median values (median=6, IQR [4;8]) were context, communication, and organisation. Night to morning handovers obtained the lowest scores. CVI-S was 0.96, Cronbach's alpha was 0.79. The Handoff CEX-Italian scale is valid and reliable and it can be used to assess the quality of nurse handovers.

Morphing Wing Weight Predictors and Their Application in a Template-Based Morphing Aircraft Sizing Environment II. Part 2; Morphing Aircraft Sizing via Multi-level Optimization

NASA Technical Reports Server (NTRS)

Skillen, Michael D.; Crossley, William A.

2008-01-01

This report presents an approach for sizing of a morphing aircraft based upon a multi-level design optimization approach. For this effort, a morphing wing is one whose planform can make significant shape changes in flight - increasing wing area by 50% or more from the lowest possible area, changing sweep 30 or more, and/or increasing aspect ratio by as much as 200% from the lowest possible value. The top-level optimization problem seeks to minimize the gross weight of the aircraft by determining a set of "baseline" variables - these are common aircraft sizing variables, along with a set of "morphing limit" variables - these describe the maximum shape change for a particular morphing strategy. The sub-level optimization problems represent each segment in the morphing aircraft's design mission; here, each sub-level optimizer minimizes fuel consumed during each mission segment by changing the wing planform within the bounds set by the baseline and morphing limit variables from the top-level problem.

Electron impact excitation of Kr XXXII

NASA Astrophysics Data System (ADS)

Aggarwal, K. M.; Keenan, F. P.; Lawson, K. D.

2009-09-01

Collision strengths (Ω) have been calculated for all 7750 transitions among the lowest 125 levels belonging to the 2s2p,2s2p,2p,2s3ℓ,2s2p3ℓ, and 2p3ℓ configurations of boron-like krypton, Kr XXXII, for which the Dirac Atomic R-matrix Code has been adopted. All partial waves with angular momentum J⩽40 have been included, sufficient for the convergence of Ω for forbidden transitions. For allowed transitions, a top-up has been included in order to obtain converged values of Ω up to an energy of 500 Ryd. Resonances in the thresholds region have been resolved in a narrow energy mesh, and results for effective collision strengths (ϒ) have been obtained after averaging the values of Ω over a Maxwellian distribution of electron velocities. Values of ϒ are reported over a wide temperature range below 107.3K, and the accuracy of the results is assessed. Values of ϒ are also listed in the temperature range 7.3⩽logTe(K)⩽9.0, obtained from the nonresonant collision strengths from the Flexible Atomic Code.

Effect of the raw material composition of fabrics on the Limiting Oxygen Index (LOI)

NASA Technical Reports Server (NTRS)

Jeler, S.; Ceric, B.

1986-01-01

The raw material composition of fabrics is one of the most important factors for LOI value. LOI value was determined in samples of varying composition composed of cellulose, protein, and synthetic fibers and their mixtures, based on ASTM D 2863-76. Cellulose fibers and their mixtures exhibited the lowest value, while synthetic fibers had the highest LOI value.

Concepts for improving the damage tolerance of composite compression panels

NASA Technical Reports Server (NTRS)

Rhodes, M. D.; Williams, J. G.

1981-01-01

The results of an experimental evaluation of graphite-epoxy composite compression panel impact damage tolerance and damage propagation arrest concepts are reported. The tests were conducted on flat plate specimens and blade-stiffened structural panels such as those used in commercial aircraft wings, and the residual strength of damaged specimens and their sensitivity to damage while subjected to in-plane compression loading were determined. Results suggest that matrix materials that fail by delamination have the lowest damage tolerance, and it is concluded that alternative matrix materials with transverse reinforcement to suppress the delamination failure mode and yield the higher-strain value transverse shear crippling mode should be developed.

The Aerodynamic Characteristics of Six Full-Scale Propellers Having Different Airfoil Sections

NASA Technical Reports Server (NTRS)

Biermann, David; Hartman, Edwin P

1939-01-01

Wind-tunnel tests are reported of six 3-blade 10-foot propellers operated in front of a liquid-cooled engine nacelle. The propellers were identical except for blade airfoil sections, which were: Clark y, R.A.F. 6, NACA 4400, NACA 2400-34, NACA 2rsub200, and NACA 6400. The range of blade angles investigated extended for 15 degrees to 40 degrees for all propellers except the Clark y, for which it extended to 45 degrees. The results showed that the range in maximum efficiency between the highest and lowest values was about 3 percent. The highest efficiencies were for the low-camber sections.

Far-Infrared Optical Conductivity Gap in Superconducting MgB2 Films

NASA Astrophysics Data System (ADS)

Kaindl, Robert A.; Carnahan, Marc A.; Orenstein, Joseph; Chemla, Daniel S.; Christen, Hans M.; Zhai, Hong-Ying; Paranthaman, Mariappan; Lowndes, Doug H.

2002-01-01

We report the first study of the optical conductivity of MgB 2 covering the range of its lowest-energy superconducting gap. Terahertz time-domain spectroscopy is utilized to determine the complex, frequency-dependent conductivity σ(ω) of thin films. The imaginary part reveals an inductive response due to the emergence of the superconducting condensate. The real part exhibits a strong depletion of oscillator strength near 5 meV resulting from the opening of a superconducting energy gap. The gap ratio of 2Δ0/kBTC~1.9 is well below the weak-coupling value, pointing to complex behavior in this novel superconductor.

Gram-scale cryogenic calorimeters for rare-event searches

NASA Astrophysics Data System (ADS)

Strauss, R.; Rothe, J.; Angloher, G.; Bento, A.; Gütlein, A.; Hauff, D.; Kluck, H.; Mancuso, M.; Oberauer, L.; Petricca, F.; Pröbst, F.; Schieck, J.; Schönert, S.; Seidel, W.; Stodolsky, L.

2017-07-01

The energy threshold of a cryogenic calorimeter can be lowered by reducing its size. This is of importance since the resulting increase in signal rate enables new approaches in rare-event searches, including the detection of MeV mass dark matter and coherent scattering of reactor or solar neutrinos. A scaling law for energy threshold vs detector size is given. We analyze the possibility of lowering the threshold of a gram-scale cryogenic calorimeter to the few eV regime. A prototype 0.5 g Al2 O3 device achieved an energy threshold of Eth=(19.7 ±0.9 ) eV , the lowest value reported for a macroscopic calorimeter.

Non-Research-Related Physician-Industry Relationships of Radiologists in the United States.

PubMed

Harvey, H Benjamin; Alkasab, Tarik K; Pandharipande, Pari V; Halpern, Elkan F; Prabhakar, Anand M; Oklu, Rahmi; Rosenthal, Daniel I; Hirsch, Joshua A; Gazelle, G Scott; Brink, James A

2015-11-01

To evaluate non-research-related, physician-industry financial relationships in the United States, in 2013, as reported pursuant to the Physician Payments Sunshine Act (a provision of the Affordable Care Act). In September 2014, CMS released the first five months (August 2013 to December 2013) of data disclosing physician-industry financial relationships. The frequency and value of non-research-related transfers in radiology were calculated and compared with those for 19 other specialties. Subanalyses of the frequency and value of such transfers in radiology were performed, based on state of licensure, radiologic subspecialty, nature of payment, manufacturer identity, and drug or device involved. A total of 7.4% (2,654 of 35,768) of radiologists from the United States had reportable non-research-related financial relationship(s) with industry during the 5-month period, the second-lowest level among the medical specialties evaluated. The average value of non-research-related transfers of value to radiologists, excluding royalties and licenses, was low ($438.71; SD: $2,912.15; median: $43.85), with <4% of radiologists receiving >$10 per month. Of all categories, that of food and beverage had the most transfers of value (86.0%; 5,655 of 6,577); royalties and licensure were associated with the greatest average value ($27,072.34; SD: $67,524.92). Although high-value relationships were rare, 57.8% (26 of 45) of radiologists who received a value >$1,000 per month held leadership positions in imaging enterprises. Less than 4% of radiologists have non-research-related financial relationships with industry that are valued at >$10 per month, suggesting that meaningful, deleterious effects of such relationships on radiology practice, if present, are infrequent. Copyright © 2015 American College of Radiology. Published by Elsevier Inc. All rights reserved.

Predictive Values of the New Sarcopenia Index by the Foundation for the National Institutes of Health Sarcopenia Project for Mortality among Older Korean Adults.

PubMed

Moon, Joon Ho; Kim, Kyoung Min; Kim, Jung Hee; Moon, Jae Hoon; Choi, Sung Hee; Lim, Soo; Lim, Jae-Young; Kim, Ki Woong; Park, Kyong Soo; Jang, Hak Chul

2016-01-01

We evaluated the Foundation for the National Institutes of Health (FNIH) Sarcopenia Project's recommended criteria for sarcopenia's association with mortality among older Korean adults. We conducted a community-based prospective cohort study which included 560 (285 men and 275 women) older Korean adults aged ≥65 years. Muscle mass (appendicular skeletal muscle mass-to-body mass index ratio (ASM/BMI)), handgrip strength, and walking velocity were evaluated in association with all-cause mortality during 6-year follow-up. Both the lowest quintile for each parameter (ethnic-specific cutoff) and FNIH-recommended values were used as cutoffs. Forty men (14.0%) and 21 women (7.6%) died during 6-year follow-up. The deceased subjects were older and had lower ASM, handgrip strength, and walking velocity. Sarcopenia defined by both low lean mass and weakness had a 4.13 (95% CI, 1.69-10.11) times higher risk of death, and sarcopenia defined by a combination of low lean mass, weakness, and slowness had a 9.56 (3.16-28.90) times higher risk of death after adjusting for covariates in men. However, these significant associations were not observed in women. In terms of cutoffs of each parameter, using the lowest quintile showed better predictive values in mortality than using the FNIH-recommended values. Moreover, new muscle mass index, ASM/BMI, provided better prognostic values than ASM/height2 in all associations. New sarcopenia definition by FNIH was better able to predict 6-year mortality among Korean men. Moreover, ethnic-specific cutoffs, the lowest quintile for each parameter, predicted the higher risk of mortality than the FNIH-recommended values.

Predictive Values of the New Sarcopenia Index by the Foundation for the National Institutes of Health Sarcopenia Project for Mortality among Older Korean Adults

PubMed Central

Kim, Jung Hee; Moon, Jae Hoon; Choi, Sung Hee; Lim, Soo; Lim, Jae-Young; Kim, Ki Woong; Park, Kyong Soo; Jang, Hak Chul

2016-01-01

Objective We evaluated the Foundation for the National Institutes of Health (FNIH) Sarcopenia Project’s recommended criteria for sarcopenia’s association with mortality among older Korean adults. Methods We conducted a community-based prospective cohort study which included 560 (285 men and 275 women) older Korean adults aged ≥65 years. Muscle mass (appendicular skeletal muscle mass-to-body mass index ratio (ASM/BMI)), handgrip strength, and walking velocity were evaluated in association with all-cause mortality during 6-year follow-up. Both the lowest quintile for each parameter (ethnic-specific cutoff) and FNIH-recommended values were used as cutoffs. Results Forty men (14.0%) and 21 women (7.6%) died during 6-year follow-up. The deceased subjects were older and had lower ASM, handgrip strength, and walking velocity. Sarcopenia defined by both low lean mass and weakness had a 4.13 (95% CI, 1.69–10.11) times higher risk of death, and sarcopenia defined by a combination of low lean mass, weakness, and slowness had a 9.56 (3.16–28.90) times higher risk of death after adjusting for covariates in men. However, these significant associations were not observed in women. In terms of cutoffs of each parameter, using the lowest quintile showed better predictive values in mortality than using the FNIH-recommended values. Moreover, new muscle mass index, ASM/BMI, provided better prognostic values than ASM/height2 in all associations. Conclusions New sarcopenia definition by FNIH was better able to predict 6-year mortality among Korean men. Moreover, ethnic-specific cutoffs, the lowest quintile for each parameter, predicted the higher risk of mortality than the FNIH-recommended values. PMID:27832145

Carbon Isotope Composition as an Indicator of DOC Sources to a Stream During Events in a Temperate Forested Catchment

NASA Astrophysics Data System (ADS)

Doctor, D. H.; Sebestyen, S. D.; Aiken, G. R.; Shanley, J. B.; Kendall, C.; Boyer, E. W.

2006-12-01

Increased DOC flux in streams and rivers is commonly observed during high runoff regimes, however DOC concentrations alone do not provide information about multiple sources or pathways of DOC to streams. In an effort to gain this information, we measured DOC concentrations and stable carbon isotope composition (δ13C-DOC) on samples collected at high-frequency during events at Sleepers River Research Watershed in Vermont, USA. During snowmelt and storm events, peaks in stream DOC concentration (up to 10.5 mg/L) were coincident with peaks in flow. Stream water δ13C-DOC measurements ranged between -23.7‰ and - 28.9‰ and indicated changing sources of DOC during events; the highest δ13C-DOC values occurred consistently at the lowest flows, and the lowest δ13C-DOC values occurred with peaks in discharge. Water samples collected from shallow wells and stacked soil lysimeters showed the highest DOC concentrations in the most shallow (<0.5 m) lysimeter waters, and the lowest concentrations in the deeper (>1.5 m) well waters. Wells and lysimeters exhibited a range of δ13C-DOC values similar to those observed in the stream; however, samples collected from shallow horizons at nested wells and lysimeters consistently showed lower δ13C-DOC values than those from greater depths. Maple leaf litter collected from across the watershed provided an end-member of fresh organic material, with average δ13C composition of -31.3±0.7‰ (n=57), which is lower than the lowest measured DOC values in any of the stream, well, or lysimeter waters. A subset of stream waters were fractionated onto XAD4 and XAD8 resins; the hydrophobic acid fraction (XAD8) had consistently lower δ13C values than the transphilic acid fraction (XAD4), and both of these were lower than those of the bulk DOC. Samples with lower δ13C-DOC values also exhibited higher SUVA-254 values, i.e. greater aromaticity. Thus, lower δ13C-DOC values are interpreted as an indicator of relatively "fresh", more aromatic and more biologically labile material while higher δ13C-DOC values indicate relatively more degraded material. Since lower δ13C-DOC values were observed in the shallowest well and lysimeter waters and in stream water during periods of highest DOC flux, we surmise that fresh DOC is mobilized to the stream along relatively shallow flowpaths during high flows, and that a second source of more degraded DOC supplies background concentrations to the stream at lower flows.

Rheological, physical and sensorial evaluation of cookies supplemented with dairy powders.

PubMed

Sert, Durmuş; Demir, M Kürşat; Ertaş, Nilgün

2016-04-01

The effect of dairy powders (skim milk powder, butter milk powder, sodium caseinate, yoghurt powder, milk powder and colostrum powder) on cookie quality was studied. Cookies were tested for aw, calorimetric energy, diameter, thickness, spread ratio, breaking strength, colour, dough consistency and sensory evaluation. The lowest aw values were obtained for cookies containing colostrum powder; also the highest calorimetric energy values were obtained from the colostrum powder-added cookies. Diameter values of cookies with the addition of skim milk powder, butter milk powder, yoghurt powder and milk powder were higher than that of sodium caseinate and colostrum powder. The lowest spread ratio was measured in the cookie samples with added skim milk powder. The addition of yoghurt powder gave the highest breaking strength of cookies. Cookies with sodium caseinate addition exhibited the highest lightness (L*) values than the other cookies with different dairy powders. Cookies prepared with butter milk powder received the highest scores for colour, appearance, texture, crispness and overall acceptability. © The Author(s) 2015.

Kepler Uniform Modeling of KOIs: MCMC Notes for Data Release 25

NASA Technical Reports Server (NTRS)

Hoffman, Kelsey L.; Rowe, Jason F.

2017-01-01

This document describes data products related to the reported planetary parameters and uncertainties for the Kepler Objects of Interest (KOIs) based on a Markov-Chain-Monte-Carlo (MCMC) analysis. Reported parameters, uncertainties and data products can be found at the NASA Exoplanet Archive . The codes used for this data analysis are available on the Github website (Rowe 2016). The relevant paper for details of the calculations is Rowe et al. (2015). The main differences between the model fits discussed here and those in the DR24 catalogue are that the DR25 light curves were used in the analysis, our processing of the MAST light curves took into account different data flags, the number of chains calculated was doubled to 200 000, and the parameters which are reported are based on a damped least-squares fit, instead of the median value from the Markov chain or the chain with the lowest 2 as reported in the past.

Association of δ¹³C in fingerstick blood with added-sugar and sugar-sweetened beverage intake.

PubMed

Davy, Brenda M; Jahren, A Hope; Hedrick, Valisa E; Comber, Dana L

2011-06-01

A reliance on self-reported dietary intake measures is a common research limitation, thus the need for dietary biomarkers. Added-sugar intake may play a role in the development and progression of obesity and related comorbidities; common sweeteners include corn and sugar cane derivatives. These plants contain a high amount of ¹³C, a naturally occurring stable carbon isotope. Consumption of these sweeteners, of which sugar-sweetened beverages are the primary dietary source, might be reflected in the δ¹³C value of blood. Fingerstick blood represents an ideal substrate for bioassay because of its ease of acquisition. The objective of this investigation was to determine if the δ¹³C value of fingerstick blood is a potential biomarker of added-sugar and sugar-sweetened beverage intake. Individuals aged 21 years and older (n = 60) were recruited to attend three laboratory visits; assessments completed at each visit depended upon a randomly assigned sequence (sequence one or two). The initial visit included assessment of height, weight, and dietary intake (sequence one: beverage intake questionnaire, sequence two: 4-day food intake record). Sequence one participants completed a food intake record at visit two, and nonfasting blood samples were obtained via routine fingersticks at visits one and three. Sequence two participants completed a beverage intake questionnaire at visit two, and provided fingerstick blood samples at visits two and three. Samples were analyzed for δ¹³C value using natural abundance stable isotope mass spectrometry. δ¹³C value was compared to dietary outcomes in all participants, as well as among those in the highest and lowest tertile of added-sugar intake. Reported mean added-sugar consumption was 66 ± 5 g/day, and sugar-sweetened beverage consumption was 330 ± 53 g/day and 134 ± 25 kcal/day. Mean fingerstick δ¹³C value was -19.94‰ ± 0.10‰, which differed by body mass index status. δ¹³C value was associated (all P < 0.05) with intake of total added sugars (g, r = 0.37; kcal, r = 0.37), soft drinks (g, r = 0.26; kcal, r = 0.27), and total sugar-sweetened beverage (g, r = 0.28; kcal, r = 0.35). The δ¹³C value in the lowest and the highest added-sugar intake tertiles were significantly different (mean difference = -0.48‰; P = 0.028). Although there are several potential dietary sources for blood carbon, the δ¹³C value of fingerstick blood shows promise as a noninvasive biomarker of added-sugar and sugar-sweetened beverage intake based on these findings. Copyright © 2011 American Dietetic Association. Published by Elsevier Inc. All rights reserved.

Agreement between child self-reported and parent-reported scores for chronic pain secondary to specific pediatric diseases.

PubMed

Díez Rodriguez-Labajo, A; Castarlenas, E; Miró, J; Reinoso-Barbero, F

2017-03-01

Parental report on a child's secondary chronic pain is commonly requested by anesthesiologists when the child cannot directly provide information. Daily pain intensity is reported as highest, average and lowest. However, it is unclear whether the parents' score is a valid indicator of the child's pain experience. Nineteen children (aged 6-18years) with secondary chronic pain attending our anesthesiologist-run pediatric pain unit participated in this study. Identification of highest, average and lowest pain intensity levels were requested during initial screening interviews with the child and parents. Pain intensity was scored on a 0-10 numerical rating scale. Agreement was examined using: (i) intraclass correlation coefficient (ICC), and (ii) the Bland-Altman method. The ICC's between the children and the parents' pain intensity reports were: 0.92 for the highest, 0.68 for the average, and 0.50 for the lowest pain intensity domains. The limits of agreement set at 95% between child and parental reports were respectively +2.19 to -2.07, +3.17 to -3.88 and +5.15 to -5.50 for the highest, average and lowest pain domains. For the highest pain intensity domain, agreement between parents and children was excellent. If replicated this preliminary finding would suggest the highest pain intensity is the easiest domain for reporting pain intensity when a child cannot directly express him or herself. Copyright © 2016 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

Global Intraurban Intake Fractions for Primary Air Pollutants from Vehicles and Other Distributed Sources

PubMed Central

2012-01-01

We model intraurban intake fraction (iF) values for distributed ground-level emissions in all 3646 global cities with more than 100 000 inhabitants, encompassing a total population of 2.0 billion. For conserved primary pollutants, population-weighted median, mean, and interquartile range iF values are 26, 39, and 14–52 ppm, respectively, where 1 ppm signifies 1 g inhaled/t emitted. The global mean urban iF reported here is roughly twice as large as previous estimates for cities in the United States and Europe. Intake fractions vary among cities owing to differences in population size, population density, and meteorology. Sorting by size, population-weighted mean iF values are 65, 35, and 15 ppm, respectively, for cities with populations larger than 3, 0.6–3, and 0.1–0.6 million. The 20 worldwide megacities (each >10 million people) have a population-weighted mean iF of 83 ppm. Mean intraurban iF values are greatest in Asia and lowest in land-rich high-income regions. Country-average iF values vary by a factor of 3 among the 10 nations with the largest urban populations. PMID:22332712

Impact of parenting styles on adolescents' self-esteem and internalization of values in Spain.

PubMed

Martínez, Isabel; García, José Fernando

2007-11-01

The relationship of parenting styles with adolescents' outcomes was analyzed within a sample of Spanish adolescents. A sample of 1456 teenagers from 13 to 16 years of age, of whom 54.3% were females, reported on their parents' child-rearing practices. The teenagers' parents were classified into one of four groups (authoritative, authoritarian, indulgent, or neglectful). The adolescents were then contrasted on two different outcomes: (1) priority given to Schwartz's self-transcendence (universalism and benevolence) and conservation (security, conformity, and tradition) values and (2) level of self-esteem (appraised in five domains: academic, social, emotional, family and physical). The results show that Spanish adolescents from indulgent households have the same or better outcomes than adolescents from authoritative homes. Parenting is related with two self-esteem dimensions--academic and family--and with all the self-transcendence and conservation values. Adolescents of indulgent parents show highest scores in self-esteem whereas adolescents from authoritarian parents obtain the worst results. In contrast, there were no differences between the priority given by adolescents of authoritative and indulgent parents to any of the self-transcendence and conservation values, whereas adolescents of authoritarian and neglectful parents, in general, assign the lowest priority to all of these values.

26 CFR 1.897-9T - Treatment of certain interest in publicly traded corporations, definition of foreign person, and...

Code of Federal Regulations, 2010 CFR

2010-04-01

... fair market value greater than the fair market value on that date of 5 percent of the regularly traded class of the corporation's stock with the lowest fair market value. However, if a non-regularly traded... if on the date it was acquired by its present holder it had a fair market value greater than the fair...

Trilateral interlaboratory with SSL (WLEDi) luminaire

NASA Astrophysics Data System (ADS)

Burini Junior, E. C.; Santos, E. R.; Assaf, L. O.

2018-03-01

The IEE/USP laboratory and two others, all belonging to RBLE (Brazilian Network of Test Laboratories) participated in a trilateral comparison performed from measurement independently of participants interaction. The results from electric and photometric measurements carried out on samples of Solid State Lighting - SSL, Inorganic White Light Emitting Diode (WLEDi) luminaires by three accredited laboratories were considered in order to point out mutual deviations and to verify the confidence in a bilateral comparison. The first analysis revealed a maximum deviation of 4.2 % between the luminous intensity attributed by one laboratory and the arithmetic mean value from three laboratories. The largest standard uncertainty value of 1.9 % was estimated for Total Harmonic Distortion of electric current THDi and the lowest value, 0.4 %, to the luminous flux. The extreme deviation for one parameter results was 7.2 % at maximum luminous intensity and the lowest was 1.7 % for luminous flux.

Partitioning of fluorotelomer alcohols to octanol and different sources of dissolved organic carbon.

PubMed

Carmosini, Nadia; Lee, Linda S

2008-09-01

Interest in the environmental fate of fluorotelomer alcohols (FTOHs) has spurred efforts to understand their equilibrium partitioning behavior. Experimentally determined partition coefficients for FTOHs between soil/water and air/water have been reported, but direct measurements of partition coefficients for dissolved organic carbon (DOC)/water (K(doc)) and octanol/ water(K(ow)) have been lacking. Here we measured the partitioning of 8:2 and 6:2 FTOH between one or more types of DOC and water using enhanced solubility or dialysis bag techniques, and also quantified K(ow) values for 4:2 to 8:2 FTOH using a batch equilibration method. The range in measured log K(doc) values for 8:2 FTOH using the enhanced solubility technique with DOC derived from two soils, two biosolids, and three reference humic acids is 2.00-3.97 with the lowest values obtained for the biosolids and an average across all other DOC sources (biosolid DOC excluded) of 3.54 +/- 0.29. For 6:2 FTOH and Aldrich humic acid, a log K(doc) value of 1.96 +/- 0.45 was measured using the dialysis technique. These average values are approximately 1 to 2 log units lower than previously indirectly estimated K(doc) values. Overall, the affinity for DOC tends to be slightly lower than that for particulate soil organic carbon. Measured log K(ow) values for 4:2 (3.30 +/- 0.04), 6:2 (4.54 +/- 0.01), and 8:2 FTOH (5.58 +/- 0.06) were in good agreement with previously reported estimates. Using relationships between experimentally measured partition coefficients and C-atom chain length, we estimated K(doc) and K(ow) values for shorter and longer chain FTOHs, respectively, that we were unable to measure experimentally.

Nonlinear association of BMI with all-cause and cardiovascular mortality in type 2 diabetes mellitus: a systematic review and meta-analysis of 414,587 participants in prospective studies.

PubMed

Zaccardi, Francesco; Dhalwani, Nafeesa N; Papamargaritis, Dimitris; Webb, David R; Murphy, Gavin J; Davies, Melanie J; Khunti, Kamlesh

2017-02-01

The relationship between BMI and mortality has been extensively investigated in the general population; however, it is less clear in people with type 2 diabetes. We aimed to assess the association of BMI with all-cause and cardiovascular mortality in individuals with type 2 diabetes mellitus. We searched electronic databases up to 1 March 2016 for prospective studies reporting associations for three or more BMI groups with all-cause and cardiovascular mortality in individuals with type 2 diabetes mellitus. Study-specific associations between BMI and the most-adjusted RR were estimated using restricted cubic splines and a generalised least squares method before pooling study estimates with a multivariate random-effects meta-analysis. We included 21 studies including 24 cohorts, 414,587 participants, 61,889 all-cause and 4470 cardiovascular incident deaths; follow-up ranged from 2.7 to 15.9 years. There was a strong nonlinear relationship between BMI and all-cause mortality in both men and women, with the lowest estimated risk from 31-35 kg/m 2 and 28-31 kg/m 2 (p value for nonlinearity <0.001) respectively. The risk of mortality at higher BMI values increased significantly only in women, whilst lower values were associated with higher mortality in both sexes. Limited data for cardiovascular mortality were available, with a possible inverse linear association with BMI (higher risk for BMI <27 kg/m 2 ). In type 2 diabetes, BMI is nonlinearly associated with all-cause mortality with lowest risk in the overweight group in both men and women. Further research is needed to clarify the relationship with cardiovascular mortality and assess causality and sex differences.

Engineered cost-effective growth of Co-based nanoflakes as a sustainable water oxidation electrocatalyst

NASA Astrophysics Data System (ADS)

Pourreza, M.; Naseri, N.

2017-11-01

Developing low-cost, scalable and reproducible synthesis methods for water oxidation reaction (WOR) catalysts is highly desirable and also challenging in energy, environmental and industrial applications. In this context, electrochemical deposition is known as an easy and cost-effective technique in nanomaterial growth. Herein, cobalt-based nanoflakes were grown on a flexible and commercially available steel mesh substrate by electrodeposition approach with a crystalline structure as a mixture of oxide, hydroxide and oxyhydroxide phases. For the first time, the correlation between electrodeposition parameters, time and current density, and morphological characteristics of the grown nanoflakes (density and aspect ratio based on SEM results) has been derived. According to a comprehensive study of the flakes’ electrocatalytic performance in WOR, the optimized sample fabricated with a moderate electrodeposition current density (7 mA cm-2) and duration time (2000 s) revealed the highest density (7.6  ×  108 cm-2) and aspect ratio (7.1) as well as the lowest values for overpotential (OP  =  324 mV) and charge transfer resistance (14 Ω). This designed array of Co-based nanoflakes also showed the lowest value of overpotential for bare cobalt-based WOR electrocatalysts reported yet. High and low values for deposition current density and/or deposition time had a negative effect on the sample surface, leaving some areas without any flakes or with incomplete and inefficient formation of nanoflakes with low densities and aspect ratios. A similar effect was observed for annealed samples in the range of 200-400 °C. Based on recorded overpotentials and extracted surface morphological parameters, a linear and logarithmic behavior in overpotential-flake density dependency was proposed for current density and time controlled systems, respectively.

Supply Chain Management: Are You Maximizing Your Procurement Activity?

ERIC Educational Resources Information Center

Dobbin, James; Jenkins, Mike

2000-01-01

Today's purchasing professionals recognize the need to reduce non-value-added procedures (clerical functions) while emphasizing strategic planning. Results-oriented supply-chain managers need superb communication, negotiation, and leadership skills to achieve long-term value and resist the lowest, first- cost bids. (Contains 13 references.) (MLH)

Development and molecular characterization of genic molecular markers for grain protein and calcium content in finger millet (Eleusine coracana (L.) Gaertn.).

PubMed

Nirgude, M; Babu, B Kalyana; Shambhavi, Y; Singh, U M; Upadhyaya, H D; Kumar, Anil

2014-03-01

Finger millet (Eleusine coracana (L.) Gaertn), holds immense agricultural and economic importance for its high nutraceuticals quality. Finger millets seeds are rich source of calcium and its proteins are good source of essential amino acids. In the present study, we developed 36 EST-SSR primers for the opaque2 modifiers and 20 anchored-SSR primers for calcium transporters and calmodulin for analysis of the genetic diversity of 103 finger millet genotypes for grain protein and calcium contents. Out of the 36 opaque2 modifiers primers, 15 were found polymorphic and were used for the diversity analysis. The highest PIC value was observed with the primer FMO2E33 (0.26), while the lowest was observed FMO2E27 (0.023) with an average value of 0.17. The gene diversity was highest for the primer FMO2E33 (0.33), however it was lowest for FMO2E27 (0.024) at average value of 0.29. The percentage polymorphism shown by opaque2 modifiers primers was 68.23%. The diversity analysis by calcium transporters and calmodulin based anchored SSR loci revealed that the highest PIC was observed with the primer FMCA8 (0.30) and the lowest was observed for FMCA5 (0.023) with an average value of 0.18. The highest gene diversity was observed for primer FMCA8 (0.37), while lowest for FMCA5 (0.024) at an average of 0.21. The opaque2 modifiers specific EST-SSRs could able to differentiate the finger millet genotypes into high, medium and low protein containing genotypes. However, calcium dependent candidate gene based EST-SSRs could broadly differentiate the genotypes based on the calcium content with a few exceptions. A significant negative correlation between calcium and protein content was observed. The present study resulted in identification of highly polymorphic primers (FMO2E30, FMO2E33, FMO2-18 and FMO2-14) based on the parameters such as percentage of polymorphism, PIC values, gene diversity and number of alleles.

Activity and physiological significance of the pleopods in the respiration of Callianassa californiensis (Dana) (Crustacea: Thalassinidea).

PubMed

Torres, J J; Gluck, D L; Childress, J J

1977-02-01

1. The pleopods of C. californiensis, a potential site for extrabranchial oxygen exchange, do not contribute significantly to oxygen consumption. 2. C. californiensis has a gill surface area of 4.13 +/- 0.72 cm2/g wet body weight, the lowest value yet reported for a totally aquatic crustacean. 3. C. californiensis, when placed in simulated burrow conditions, regulates the PO2 very loosely in its immediate microhabitat, using its pleopods. 4. Field studies of pH and PO2 values in burrows of C. californiensis indicate that animal movement may play a large part in water exchange between the surface and burrow. 5. Activity studies suggest that oxygen is not critical to C. californiensis on a short term basis. Perception of oxygen after long deprivation may signal the possibility of renewed feeding and activity at the surface of its burrow.

Role of polymer matrix on photo-sensitivity of CdSe polymer nanocomposites

NASA Astrophysics Data System (ADS)

Kaur, Ramneek; Tripathi, S. K.

2018-04-01

This paper reports the effect of three different polymer matrices (PVP, PMMA and PVK) and Ag doping on the photo-sensitivity of CdSe polymer nanocomposites. The results reveal that the photoconductivity is high for linear chain polymer nanocomposites as compared to aromatic ones with decreasing trend as: CdSe-PMMA > CdSe-PVP > CdSe-PVK. The large substituents or branches along the polymer backbone hinder the stacking sequences in CdSe-PVK nanocomposites resulting in lowest photoconductivity. On contrary, CdSe-PVK nanocomposite exhibit highest photosensitivity. The reason behind it is the low value of dark conductivity in CdSe-PVK nanocomposite and photoconductive PVK matrix. With Ag doping, no considerable effect on the value of photosensitivity has been observed. The obtained results indicate that the photo-conducting properties of these polymer nanocomposites can be tuned by using different polymer matrices.

Complexity of Exercise Behavior Among Older African American Women.

PubMed

Kosma, Maria; Buchanan, David; Hondzinski, Jan

2017-07-01

Despite the exercise benefits, disparities among diverse older adults continue to exist, where African American women have the lowest percentage of any population group in meeting national recommended activity guidelines. Drawing on the philosophical tradition of phronesis (practical reasoning) introduced by Aristotle, we studied perceptions of the exercise value among 14 older African American women. Three themes included: (1) exercise goals (e.g., effort exerted), (2) exercise reasons (e.g., health benefits, enjoyment and convenience, and activity recommendation), and (3) inactivity reasons (e.g., health issues, lack of motivation, and family responsibilities/priorities). Although most women reported being active, only three participants met the Healthy People 2020 guidelines for aerobic and muscle-strengthening activities, while two individuals were inactive. Exercise promoters should consider the values that motivate older African American women to exercise, such as the provision of accessible, nondiscriminatory exercise facilities, and not to exercise, such as concerns about neighborhood safety, in designing programs.

Interaural attenuation for Sennheiser HDA 200 circumaural earphones.

PubMed

Brännström, K Jonas; Lantz, Johannes

2010-06-01

Interaural attenuation (IA) was evaluated for pure tones (frequency range 125 to 16000 Hz) using Sennheiser HDA 200 circumaural earphones and Telephonics TDH-39P earphones in nine unilaterally deaf subjects. Audiometry was conducted in 1-dB steps using the manual ascending technique in accordance with ISO 8253-1. For all subjects and for all tested frequencies, the lowest IA value for HDA 200 was 42 dB. The present IA values for TDH-39P earphones closely resemble previously reported data. The findings show that the HDA 200 earphones provide more IA than the TDH-39P, especially at lower frequencies (

7 CFR 1415.10 - Compensation for easements and rental contracts acquired by the Secretary.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Secretary. (a) The Chief shall not pay more than the fair market value of the land, less the grazing value... compensation the lowest of: (1) The fair market value of the land encumbered by the easement as determined by... market analysis or market survey. (2) The amount corresponding to a geographical cap, as determined by...

Stable isotope records of inland California megafauna - new insights into Pleistocene paleoecology and paleoenvironmental conditions

NASA Astrophysics Data System (ADS)

Trayler, R. B.; Dundas, R. G.; Van De Water, P. K.; Fox-Dobbs, K.

2012-12-01

Paleodietary studies of California megafauna have focused primarily on the coastal late Pleistocene Rancho La Brea tar seeps (RLB) in Los Angeles, while other sites remain understudied. We examined two Pleistocene fossil localities from inland California (San Joaquin Valley) and report δ13C and δ18O values measured from tooth enamel of mammalian megafauna at both sites. The late Pleistocene McKittrick tar seeps in Kern County has a similar fauna to RLB. The middle Irvingtonian (~700,000 year old) Fairmead Landfill site, near Chowchilla, contains a megafaunal assemblage dominated by Equus, Camelops and Mammuthus. We used stable isotope values measured in carnivore and herbivore tooth enamel to investigate paleodietary and paleoecological patterns at both sites. δ13C values of tooth enamel is controlled by diet and can be used to investigate resource usage and partitioning among and between taxa. In large mammals δ18O ratios are controlled by drinking water, and by proxy, climate. Ontogenetic serial tooth δ18O and δ13C reveal seasonal trends in resource usage, from which we can infer patterns of forage availability. We sampled 85 individuals from 16 taxa; Arctodus, Bison, Camelops, Canis, Capromeryx, Cervus, Equus, Hemiauchenia, Homotherium, Mammut, Mammuthus, Miracinonyx, Panthera, Platygonus, Smilodon and Tetrameryx. Faunal δ13C differ significantly (p<0.001) between Fairmead and McKittrick, ranging from -13.5‰ to -8.2‰ and -11.8 to -0.7‰, respectively. No significant differences were detected in δ18O between sites (p=0.7). Fairmead δ13C values are consistent with an environment dominated by C3 vegetation. Platygonus and Camelops had the lowest and highest δ13C, respectively. Camelops exhibited the most variable δ13C among herbivores, though several other taxa are represented by single individuals, thus lacking dietary ranges. Among carnivores, Smilodon had the lowest δ13C values (-13.4‰) and Canis latrans the highest (-10.7‰). Carnivore δ13C values only partially overlap the observed range of herbivore values suggesting that not all herbivores were consumed with the same frequency. In comparison to Fairmead, δ13C values from McKittrick show a significant shift in isotopic values suggesting greater C4 plant availability from middle to late Pleistocene. Camelops showed the greatest shift towards C4 plants values, while Cervus had the most negative δ13C value indicating the presence of woodland C3 resources. Within the carnivore guild, Panthera and Arctodus had specialized diets trending towards forested habitats, while canids exhibit generalist diets. We serially sampled multiple teeth from both sites to investigate seasonality and temporal resource usage among megafauna. Equus from both localities showed little variation in δ13C, while at McKittrick Camelops diet included variable amounts of C4 resources throughout a seasonal cycle. We also report the first ever serial sampled Tetrameryx tooth; δ13C variation throughout the tooth is low suggesting a stable diet. Comparing similarly aged inland McKittrick and coastal RLB faunas reveal significant differences (p<0.001). Bison, Equus (Feranec et al., 2009) and Panthera show statistically similar dietary δ13C while Camelops, Canis dirus, Canis latrans and Mammut show significant differences from previously reported RLB analogs (Coltrain et al., 2004).

Standardized UV-vis spectra as the foundation for a threshold-based, integrated photosafety evaluation.

PubMed

Bauer, Daniel; Averett, Lacey A; De Smedt, Ann; Kleinman, Mark H; Muster, Wolfgang; Pettersen, Betty A; Robles, Catherine

2014-02-01

Phototoxicity is a relatively common phenomenon and is an adverse effect of some systemic drugs. The fundamental initial step of photochemical reactivity is absorption of a photon; however, little guidance has been provided thus far regarding how ultraviolet-visible (UV-vis) light absorption spectra may be used to inform testing strategies for investigational drugs. Here we report the results of an inter-laboratory study comparing the data from harmonized UV-vis light absorption spectra obtained in methanol with data from the in vitro 3T3 Neutral Red Uptake Phototoxicity Test. Six pharmaceutical companies submitted data according to predefined quality criteria for 76 compounds covering a wide range of chemical classes showing a diverse but "positive"-enhanced distribution of photo irritation factors (22%: PIF<2, 12%: PIF 2-5, 66%: PIF>5). For compounds being formally positive (PIF value above 5) the lowest reported molar extinction coefficient (MEC) was 1700 L mol⁻¹ cm⁻¹ in methanol. However, the majority of these formally positive compounds showed MEC values being significantly higher (up to almost 40,000 L mol⁻¹ cm⁻¹). In conclusion, an MEC value of 1000 L mol⁻¹ cm⁻¹ may represent a reasonable and pragmatic threshold warranting further experimental photosafety evaluation. Copyright © 2013 Elsevier Inc. All rights reserved.

Marginal Gaps between 2 Calcium Silicate and Glass Ionomer Cements and Apical Root Dentin.

PubMed

Biočanin, Vladimir; Antonijević, Đorđe; Poštić, Srđan; Ilić, Dragan; Vuković, Zorica; Milić, Marija; Fan, Yifang; Li, Zhiyu; Brković, Božidar; Đurić, Marija

2018-05-01

The outcome of periapical surgery has been directly improved with the introduction of novel material formulations. The aim of the study was to compare the retrograde obturation quality of the following materials: calcium silicate (Biodentine; Septodont, Saint-Maur-des-Fosses, France), mineral trioxide aggregate (MTA+; Cerkamed Company, Stalowa Wola, Poland), and glass ionomer cement (Fuji IX; GC Corporation, Tokyo, Japan). Materials' wettability was calculated concerning the contact angles of the cements measured using a glycerol drop. Cements' porosity was determined using mercury intrusion porosimetry and micro-computed tomographic (μCT) imaging. Extracted upper human incisors were retrofilled, and μCT analysis was applied to calculate the volume of the gap between the retrograde filling material and root canal dentin. Experiments were performed before and after soaking the materials in simulated body fluid (SBF). No statistically significant differences were found among the contact angles of the studied materials after being soaked in SBF. The material with the lowest nanoporosity (Fuji IX: 2.99% and 4.17% before and after SBF, respectively) showed the highest values of microporosity (4.2% and 3.1% before and after SBF, respectively). Biodentine had the lowest value of microporosity (1.2% and 0.8% before and after SBF, respectively) and the lowest value of microgap to the root canal wall ([10 ± 30] × 10 -3  mm 3 ). Biodentine and MTA possess certain advantages over Fuji IX for hermetic obturation of retrograde root canals. Biodentine shows a tendency toward the lowest marginal gap at the cement-to-dentin interface. Copyright © 2018 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

Evolution of collectivity near mid-shell from excited-state lifetime measurements in rare earth nuclei

NASA Astrophysics Data System (ADS)

Werner, V.; Cooper, N.; Régis, J.-M.; Rudigier, M.; Williams, E.; Jolie, J.; Cakirli, R. B.; Casten, R. F.; Ahn, T.; Anagnostatou, V.; Berant, Z.; Bonett-Matiz, M.; Elvers, M.; Heinz, A.; Ilie, G.; Radeck, D.; Savran, D.; Smith, M. K.

2016-03-01

The B (E 2 ) excitation strength of the first excited 2+ state in even-even nuclei should directly correlate with the size of the valence space and maximize at mid-shell. A previously found saturation of B (E 2 ) strengths in well-deformed rotors at mid-shell is tested through high-precision measurements of the lifetimes of the lowest-lying 2+ states of the 168Hf and 174W rare earth isotopes. Measurements were performed using fast LaBr3 scintillation detectors. Combined with the recently remeasured B (E 2 ;21+→01+) values for Hf and W isotopes the new data remove discrepancies observed in the differentials of B (E 2 ) values for these isotopes.

Early history of the moon: Implications of U-Th-Pb and Rb-Sr systematics

NASA Technical Reports Server (NTRS)

Tatsumoto, M.; Numes, P. D.; Unruh, D. M.

1977-01-01

Anorthosite 60015 contains the lowest initial Sr-87/Sr-86 ratio yet reported for a lunar sample. The initial ratio is equal to that of the achondrite Angra dos Reis and slightly higher than the lowest measured Sr-87/Sr-86 ratio for an inclusion in the C3 carbonaceous chondrite Allende. The Pb-Pb ages of both Angra does Reis and Allende are 4.62 X 10 to the ninth power yr. Thus, the initial Sr/87/Sr-86 ratio found in lunar anorthosite 60015 strongly supports the hypothesis that the age of the Moon is about 4.65 b.y. The U-238/Pb-204 value estimated for the source of the excess lead in "orange soil" 74220 is approximately 35 and lower than the values estimated for the sources of KREEP (600-1000), high-K (300-600), and low-K (100-300) basalts. From these and other physical, chemical and petrographic results it was hypothesized that (1) the moon formed approximately 4.65 b.y. ago; (2) a global-scale gravitational differentiation occurred at the beginning of lunar history; and (3) the differentiation resulted in a radical chemical and mineralogical zoning in which the U-238/Pb-204 ratios increased toward the surface, with the exception of the low U-238/Pb-204 surficial anorthositic layer which "floated" at the beginning of the differentiation relative to the denser pyroxene-rich material.

National Beef Tenderness Survey-2010: Warner-Bratzler shear force values and sensory panel ratings for beef steaks from United States retail and food service establishments.

PubMed

Guelker, M R; Haneklaus, A N; Brooks, J C; Carr, C C; Delmore, R J; Griffin, D B; Hale, D S; Harris, K B; Mafi, G G; Johnson, D D; Lorenzen, C L; Maddock, R J; Martin, J N; Miller, R K; Raines, C R; VanOverbeke, D L; Vedral, L L; Wasser, B E; Savell, J W

2013-02-01

The tenderness and palatability of retail and food service beef steaks from across the United States (12 cities for retail, 5 cities for food service) were evaluated using Warner-Bratzler shear (WBS) and consumer sensory panels. Subprimal postfabrication storage or aging times at retail establishments averaged 20.5 d with a range of 1 to 358 d, whereas postfabrication times at the food service level revealed an average time of 28.1 d with a range of 9 to 67 d. Approximately 64% of retail steaks were labeled with a packer/processor or store brand. For retail, top blade had among the lowest (P < 0.05) WBS values, whereas steaks from the round had the greatest (P < 0.05) values. There were no differences (P > 0.05) in WBS values between moist-heat and dry-heat cookery methods for the top round and bottom round steaks or between enhanced (contained salt or phosphate solution) or nonenhanced steaks. Food service top loin and rib eye steaks had the lowest (P < 0.05) WBS values compared with top sirloin steaks. Retail top blade steaks and food service top loin steaks received among the greatest (P < 0.05) consumer sensory panel ratings compared with the other steaks evaluated. Prime food service rib eye steaks received the greatest ratings (P < 0.05) for overall like, like tenderness, tenderness level, like juiciness, and juiciness level, whereas ungraded rib eye steaks received the lowest ratings (P < 0.05) for like tenderness and tenderness level. The WBS values for food service steaks were greater (P < 0.05) for the Select and ungraded groups compared with the Prime, Top Choice, and Low Choice groups. The WBS values and sensory ratings were comparable to the last survey, signifying that no recent or substantive changes in tenderness have occurred.

Study of the effect of electromagnetic fields on indoor and outdoor radon concentrations

NASA Astrophysics Data System (ADS)

Haider, Lina M.; Shareef, N. R.; Darwoysh, H. H.; Mansour, H. L.

2018-05-01

In the present work, the effect of electromagnetic fields produced by high voltage power lines(132kV) and indoor equipments on the indoor and outdoor average radon concentrations in Al-Kazaliya and Hay Al-Adil regions in Baghdad city were studied using CR-39 track detectors and a gauss-meter.Results of measurements of the present study, have shown that the highest value for the indoor average radon concentration (76.56± 8.44 Bq / m3) was recorded for sample A1(Hay Al-Adel) at a distance of (20 m) from the high voltage power lines, while the lowest value for the indoor average radon concentration (30.46 ± 8.44 Bq / m3) was recorded for sample A3 (Hay Al-Adil) at a distance of (50 m) from the high voltage power lines. The indoor gaussmeter measurements were found to be ranged from (30.2 mG) to (38.5 mG). The higest value for outdoor average radon concentration and the highest gaussmeter measurements were found for sample (1), with values (92.63 ±11.2 Bq / m3) and (87.24 ± 2.85 mG), directly under the high voltage power lines respectively, while the lowest outdoor average radon concentration and the lowest gaussmeter measurements were found in sample (4),with values (34.19 ± 6.33 Bq / m3) and (1.16 ± 0.14 Bq / m3),), at a distance of (120 m) from the high voltage power lines respectively. The results of the present work have shown that there might be an influence of the electromagnetic field on radon concentrations in areas which were close to high voltage power lines and houses which have used many electric equipment for a long period of time.

Mapping of Nitrate, Phospat And Zooxanthelae With Abundance Of Sea Urchins on Massive Coral Reef in Karimunjawa Island

NASA Astrophysics Data System (ADS)

Suryanti, S.; Ain, C.; Latifah, N.

2018-02-01

Coral reefs have high organic productivity because coral reefs can withstand nutrients and accommodate all external inputs. Many factors affect the life of corals, which is nitrate, phosphate and zooxanthellae. The purpose of this study are to know mapping of the content and the relationship between of nitrate, phosphate, zooxanthellae and abundance of sea urchins on massive coral reefs in Karimunjawa Islands. This research was conducted in May - June 2017 in three stations are Karimunjawa, Menjangan Kecil and Cemara Kecil Island. The method used in this research is survey method with quantitative approach. Results of mapping of nitrate contents on massive corals on all three islands showed the highest nitrate content on Cemara Kecil Island and lowest on Karimunjawa island, with a range of values 5.078-212.853 mg/kg. In mapping the distribution of phosphate content in the three islands showed the highest phosphate content in Menjangan Kecil island and the lowest on Karimunjawa island, with a range of values from 6.78-19.35 mg/kg. Zooxanthelae map shows that the highest and lowest distribution of zooxanthela content on Karimunjawa island, with a range of values 2.84-8.88 cell/cm2. The sea urchins found in Karimunjawa Islands during the study were Diadema setosum and Echinothrix calamaris with a range of values 5-147. Based on multiple regression analysis showed that the relationship between nitrate, phosphate and zooxanthela with abundance of sea urchins showed a strong correlation result with correlation value (r) is 0.64. These results can be an indicator of coastal environmental health, especially coral reef ecosystems.

Statistical procedures for determination and verification of minimum reporting levels for drinking water methods.

PubMed

Winslow, Stephen D; Pepich, Barry V; Martin, John J; Hallberg, George R; Munch, David J; Frebis, Christopher P; Hedrick, Elizabeth J; Krop, Richard A

2006-01-01

The United States Environmental Protection Agency's Office of Ground Water and Drinking Water has developed a single-laboratory quantitation procedure: the lowest concentration minimum reporting level (LCMRL). The LCMRL is the lowest true concentration for which future recovery is predicted to fall, with high confidence (99%), between 50% and 150%. The procedure takes into account precision and accuracy. Multiple concentration replicates are processed through the entire analytical method and the data are plotted as measured sample concentration (y-axis) versus true concentration (x-axis). If the data support an assumption of constant variance over the concentration range, an ordinary least-squares regression line is drawn; otherwise, a variance-weighted least-squares regression is used. Prediction interval lines of 99% confidence are drawn about the regression. At the points where the prediction interval lines intersect with data quality objective lines of 50% and 150% recovery, lines are dropped to the x-axis. The higher of the two values is the LCMRL. The LCMRL procedure is flexible because the data quality objectives (50-150%) and the prediction interval confidence (99%) can be varied to suit program needs. The LCMRL determination is performed during method development only. A simpler procedure for verification of data quality objectives at a given minimum reporting level (MRL) is also presented. The verification procedure requires a single set of seven samples taken through the entire method procedure. If the calculated prediction interval is contained within data quality recovery limits (50-150%), the laboratory performance at the MRL is verified.

Shear bond strength of one-step self-etch adhesives: pH influence

PubMed Central

Poggio, Claudio; Beltrami, Riccardo; Scribante, Andrea; Colombo, Marco; Chiesa, Marco

2015-01-01

Background: The aim of this study was to compare the shear bond strength of four one-step self-etch adhesives with different pH values to enamel and dentin. Materials and Methods: In this in vitro study, 200 bovine permanent mandibular incisors were used. Four one-step self-etch adhesives with different pH values were tested both on enamel and on dentin: Adper™ Easy Bond Self-Etch Adhesive (pH = 0.8-1), Futurabond NR (pH=2), G-aenial Bond (pH = 1.5), Clearfil S3 Bond (pH = 2.7). After adhesive systems application, a nanohybrid composite resin was inserted into the bonded surface. The specimens were placed in a universal testing machine. The shear bond strength was performed at a cross-head speed of 1 mm/min until the sample rupture. The shear bond strength values (MPa) of the different groups were compared with analysis of variance after that Kolmogorov and Smirnov tests were applied to assess normality of distributions. P < 0.05 was considered as significant. Results: In enamel shear bond strength, the highest shear bond strength values were reported with Futurabond NR (P < 0.01); however, no significant differences were found with Clearfil S3 Bond. The others adhesive systems showed lower shear bond strength values with significant differences between them (P < 0.05). When comparing the dentin shear bond strength, the lowest shear bond strength values were reported with Clearfil S3 Bond (P < 0.05), while there were no significant differences among the other three products (P > 0.05). Conclusion: The pH values of adhesive systems did not influence significantly their shear bond strength to enamel or dentin. PMID:26005459

Exciplex Formation between Silver Ions and the Lowest MLCT Excited State of the Tris(Bipyrazine)Ruthenium(2) Cation

DTIC Science & Technology

1988-07-11

OFFICE OF NAVAL RESEARCH Contract N00014-84-G-0201 Task No. 0051-865 0 Technical Report #21 Exciplex Formation Between Silver Ions and the Lowest...ELEMENT NO-. NO NO ~ ACCESSION NO 11. TITLE (include Security Classification) Exciplex Formation Between Silver Ions and the Lowest MLCT Excited State of... eXCiplexes with upIV to six silver ions per excited Cation. Lifetime, wavelength data are presented as a function of the [Agi/[Ru] ratio. An excited state

Calibration of satellite sensors after launch

NASA Technical Reports Server (NTRS)

Fraser, R. S.; Kaufman, Y. J.

1986-01-01

A simple and accurate method for the postflight calibration of satellite Visible Infrared Spin-Scan Radiometers (VISSR) is presented, and the results of inflight testing are reported. The calibration source for the VISSR with its effective wavelength of 610 nm is the radiance of sunlight, measured in calibrated reflectance units, scattered by the atmospheric gas above ocean which is far from land. Only the lowest 20 percent of the full-scale VISSR response is calibrated. VISSR testing aboard two geostationary operational evironmental satellites between 1980 and 1983 showed significant calibration coefficient variations of only + or - 12 percent and + or - 2 percent. Good agreement was found between values of aerosol optical thickness measured by VISSR and those measured from the ground.

Shock Hugoniot of single crystal copper

NASA Astrophysics Data System (ADS)

Chau, R.; Stölken, J.; Asoka-Kumar, P.; Kumar, M.; Holmes, N. C.

2010-01-01

The shock Hugoniot of single crystal copper is reported for stresses below 66 GPa. Symmetric impact experiments were used to measure the Hugoniots of three different crystal orientations of copper, [100], [110], and [111]. The photonic doppler velocimetry (PDV) diagnostic was adapted into a very high precision time of arrival detector for these experiments. The measured Hugoniots along all three crystal directions were nearly identical to the experimental Hugoniot for polycrystalline Cu. The predicted orientation dependence of the Hugoniot from molecular dynamics calculations was not observed. At the lowest stresses, the sound speed in Cu was extracted from the PDV data. The measured sound speeds are in agreement with values calculated from the elastic constants for Cu.

Ethnopharmacological importance of medicinal flora from the district of Vehari, Punjab province, Pakistan.

PubMed

Ahmed, Nadeem; Mahmood, Adeel; Mahmood, Aqeel; Sadeghi, Zahra; Farman, Muhammad

2015-06-20

Ethnopharmacological studies are important for the discovery of new drugs from reported indigenous flora. The current study was aimed to document medicinal flora and its therapeutic actions along with the relative importance in local health care system of the district of Vehari, Punjab province, Pakistan. Rapid appraisal approach (RAA) and semi structured interviews were used along with the group meetings with herbalists, local inhabitants and landowners to collect the relevant data. A total 77 medicinal plants belonging to 41 families disseminated among 71 genera were reported. Fabaceae was the predominant family over others with 9 reported medicinal plant species. Use frequency of leaves was at peak with 30.12% followed by stem 24.62%, fruit 14.22%, flower 12.97%, seeds 12.13%, bark 4.6% and pod 1.25%, in herbal preparations. Allium cepa exhibited the highest use value (0.90) while lowest use value (UV) was reflected by Aerva javanica (0.10). Documentation of various medicinal plants for the treatment of cancer, hepatitis and cardiac disorders is evidence in favor to highlight the value of medicinal flora. Unfortunately, no attention has been paid to this treasure in term of conservation and utilization in modern healthcare system, where these plants can be a best replacement of chemically synthesized drugs. It is also recommended that plants exhibiting high UV should be screened for detailed bio-active phytochemicals. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Adsorption, desorption and mobility of metsulfuron-methyl in soils of the oil palm agroecosystem in Malaysia.

PubMed

Ismail, B S; Ooi, K E

2012-05-01

Laboratory experiments were conducted to evaluate adsorption, desorption and mobility of metsulfuron-methyl in soils of the oil palm agroecosystem consisting of the Bernam, Selangor, Rengam and Bongor soil series. The lowest adsorption of metsulfuron-methyl occurred in the Bongor soil (0.366 ml g(-1)), and the highest in the Bemam soil (2.837 ml g(-1). The K(fads) (Freundlich) values of metsulfuron-methyl were 0.366, 0.560, 1.570 and 2.837 ml g(-1) in Bongor, Rengam, Selangor and Bemam soil, respectively. The highest K(fdes) value of metsulfuron-methyl, observed in the Bemam soil, was 2.563 indicating low desorption 0.280 (relatively strong retention). In contrast, the lowest K(fdes) value of 0.564 was observed for the Bongor soil, which had the lowest organic matter (1.43%) and clay content (13.2%). Soil organic matter and clay content were the main factors affecting the adsorption of metsulfuron-methyl. The results of the soil column leaching studies suggested that metsulfuron-methyl has a moderate potential for mobility in the Bernam and Bongor soil series with 19.3% and 39%, respectively for rainfall at 200 mm. However, since metsulfuron-methyl is applied at a very low rate (the maximum field application rate used was 30 g ha(-1)) and is susceptible to biodegradation, the potential forground water contamination is low.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Demidov, V. E.; Dzyapko, O.; Demokritov, S. O.

The room-temperature dynamics of a magnon gas driven by short microwave pumping pulses is studied. An overpopulation of the lowest energy level of the system following the pumping is observed. Using the sensitivity of the Brillouin light scattering technique to the coherence degree of the scattering magnons we demonstrate the spontaneous emergence of coherence of the magnons at the lowest level, if their density exceeds a critical value. This finding is clear proof of the quantum nature of the observed phenomenon and direct evidence of Bose-Einstein condensation of magnons at room temperature.

Influence of a diet enriched with virgin olive oil or butter on mouse gut microbiota and its correlation to physiological and biochemical parameters related to metabolic syndrome.

PubMed

Prieto, Isabel; Hidalgo, Marina; Segarra, Ana Belén; Martínez-Rodríguez, Ana María; Cobo, Antonio; Ramírez, Manuel; Abriouel, Hikmate; Gálvez, Antonio; Martínez-Cañamero, Magdalena

2018-01-01

The type of fat in the diet determinates the characteristics of gut microbiota, exerting a major role in the development of metabolic syndrome. We hypothesize that a diet enriched with extra virgin olive oil (EVOO) has a distinctive effect on the intestinal microbiome in comparison with an enriched butter diet (BT) and this effect is related to the physiological benefits exerted by EVOO. Swiss Webster mice were fed standard (SD) or two high fat diets enriched with EVOO or butter. Hormonal, physiological and metabolic parameters were evaluated. At the end of the feeding period, DNA was extracted from faeces and the 16S rRNA genes were pyrosequenced. Among the main significant differences found, BT triggered the highest values of systolic blood pressure, correlating positively with the percentage of Desulfovibrio sequences in faeces, which in turn showed significantly higher values in BT than in EVOO. EVOO had the lowest values of plasmatic insulin, correlating inversely with Desulfovibrio, and had the lowest plasmatic values of leptin which correlated inversely with Sutterellaceae, Marispirillum and Mucilaginibacter dageonensis, the three showing significantly higher percentages in EVOO. The lowest total cholesterol levels in plasma were detected in SD, correlating positively with Prevotella and Fusicatenibacter, both taxa with significantly greater presence in SD. These results may be indicative of a link between specific diets, certain physiological parameters and the prevalence of some taxa, supporting the possibility that in some of the proposed effects of virgin olive oil the modulation of intestinal microbiota could be involved.

Influence of a diet enriched with virgin olive oil or butter on mouse gut microbiota and its correlation to physiological and biochemical parameters related to metabolic syndrome

PubMed Central

Prieto, Isabel; Hidalgo, Marina; Segarra, Ana Belén; Martínez-Rodríguez, Ana María; Cobo, Antonio; Ramírez, Manuel; Abriouel, Hikmate; Gálvez, Antonio

2018-01-01

The type of fat in the diet determinates the characteristics of gut microbiota, exerting a major role in the development of metabolic syndrome. We hypothesize that a diet enriched with extra virgin olive oil (EVOO) has a distinctive effect on the intestinal microbiome in comparison with an enriched butter diet (BT) and this effect is related to the physiological benefits exerted by EVOO. Swiss Webster mice were fed standard (SD) or two high fat diets enriched with EVOO or butter. Hormonal, physiological and metabolic parameters were evaluated. At the end of the feeding period, DNA was extracted from faeces and the 16S rRNA genes were pyrosequenced. Among the main significant differences found, BT triggered the highest values of systolic blood pressure, correlating positively with the percentage of Desulfovibrio sequences in faeces, which in turn showed significantly higher values in BT than in EVOO. EVOO had the lowest values of plasmatic insulin, correlating inversely with Desulfovibrio, and had the lowest plasmatic values of leptin which correlated inversely with Sutterellaceae, Marispirillum and Mucilaginibacter dageonensis, the three showing significantly higher percentages in EVOO. The lowest total cholesterol levels in plasma were detected in SD, correlating positively with Prevotella and Fusicatenibacter, both taxa with significantly greater presence in SD. These results may be indicative of a link between specific diets, certain physiological parameters and the prevalence of some taxa, supporting the possibility that in some of the proposed effects of virgin olive oil the modulation of intestinal microbiota could be involved. PMID:29293629

Exploring Effects of C2 Warfare on C2 Ability in a Simulated Environment

DTIC Science & Technology

2011-06-01

Principal Axis Factoring, Oblimin rotation with Kaiser Normalization) included all prerequisites, but not the total value of C2 ability ( KMO = .84...Mission intent had the lowest value in this factor, a separate factor analysis was conducted on this factor ( KMO = .75; Bartlett’s test of

LES Is More: (When Evaluating Training)

ERIC Educational Resources Information Center

Ward, Sarah; Parkin, Godfrey; Medsker, Karen

2006-01-01

How paradoxical that evaluation, the main purpose of which is to establish value, often seems to return to the lowest value of anything that people do! Too commonly, in the authors' experience, evaluation is avoided or paid as little attention as possible. Due to its typically unloved nature, evaluation can be trapped in a low-level, minimalist…

Capture of complexity of specialty care in pediatric cardiology by work RVU measures.

PubMed

Bergersen, Lisa; Gauvreau, Kimberlee; McElhinney, Doff; Fenwick, Sandra; Kirshner, David; Harding, Julie; Hickey, Patricia; Mayer, John; Marshall, Audrey

2013-02-01

We sought to determine the relationship between relative value units (RVUs) and intended measures of work in catheterization for congenital heart disease. RVU was determined by matching RVU values to Current Procedural Terminology codes generated for cases performed at a single institution. Differences in median case duration, radiation exposure, adverse events, and RVU values by risk category and cases were assessed. Interventional case types were ranked from lowest to highest median RVU value, and correlations with case duration, radiation dose, and a cases-predicted probability of an adverse event were quantified with the Spearman rank correlation coefficient. Between January 2008 and December 2010, 3557 of 4011 cases were identified with an RVU and risk category designation, of which 2982 were assigned a case type. Median RVU values, radiation dose, and case duration increased with procedure risk category. Although all diagnostic cases had similar RVU values (median 10), adverse event rates ranged from 6% to 21% by age group (P < .001). Median RVU values ranged from 9 to 54 with the lowest in diagnostic and biopsy cases and increasing with isolated and then multiple interventions. Among interventional cases, no correlation existed between ranked RVU value and case duration, radiation dose, or adverse event probability (P = .13, P = .62, and P = .43, respectively). Time, skill, and stress inherent to performing catheterization procedures for congenital heart disease are not captured by measurement of RVU alone.

[Research of the Epworth sleepiness scale based on ruzzy comprehensive evaluation].

PubMed

Li, P; Lv, Y H; Ma, L; Yang, S H; Xiang, Y; Lei, Q; Du, G D; Huang, D J

2017-03-05

Objective: This research explores the effect of Epworth sleepiness scale (ESS) items on domestic patients. Method: Four thousand six hundred and thirty-three suspected OSAHS patients with snoring were selected from respiratory sleep center in the first people's hospital, Yunnan province, between January 2006 and December 2012. These patients filled in the ESS before PSG test. Firstly, these questionnaires were preprocessed, and the null and incorrect ones were deleted. Then, the fuzzy comprehensive evaluation was applied for the value of each item in ESS. Finally, the reliability was compared between before and after the removal of the lowest values. Result: Fuzzy comprehensive evaluation results show that the total value is 1.016, the item value of Sitting and talking to someone and In a car, while stopped for a few minutes in traffic is the lowest, which is 0.131. The result of reliability analysis shows that the value increases 0.2% after the two items being deleted. Conclusion: Some items of ESS are not suitable for Chinese patients, and they need to be deleted or modified to improve the screening efficiency. Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.

Ab initio studies of dissociative recombination

NASA Technical Reports Server (NTRS)

Guberman, Steven L.

1989-01-01

Quantum chemical calculations of the dissociative recombination of O2(+) and N2(+) are reported. An approach for calculating autoionization widths from high-principal-quantum-number Rydberg states is summarized, and an example is presented for the lowest dissociative state of O2. For O2(+), the 1Sigma(+)u state is the sole source of O(1S) from the lowest 10 vibrational levels of the ion. Rate coefficients for generating O(1S) and O(1D) at ionospheric temperatures are reported.

Variations in incubator temperature and humidity management: a survey of current practice.

PubMed

Deguines, C; Décima, P; Pelletier, A; Dégrugilliers, L; Ghyselen, L; Tourneux, P

2012-03-01

To describe and assess routine procedures and practices for incubator temperature and humidity management in France in 2009. A questionnaire was sent to all the 186 neonatal care units in France. The questionnaire return rate was 86%. Seventy-five per cent of the units preferred skin servo-control to air temperature control in routine practice. Air temperature control was mainly used for infants with a gestational age of more than 28 weeks and aged over 7 days of life. In general, thermal management decisions did not depend on the infant's age but were based on a protocol applied specifically by each unit. All units humidified the incubator air, but there was a large difference between the lowest and highest reported humidity values (45% and 100% assumed to be a maximal value, respectively). More than 65% of the units used a fixed humidity value, rather than a variable, protocol-derived value. We observed large variations in incubator temperature and humidity management approaches from one neonatal care unit to another. There is a need for more evidence to better inform practice. A task force should be formed to guide clinical practice. © 2011 The Author(s)/Acta Paediatrica © 2011 Foundation Acta Paediatrica.

Surface measurements of upper tropospheric water vapor isotopic composition on the Chajnantor Plateau, Chile

NASA Astrophysics Data System (ADS)

Galewsky, Joseph; Rella, Christopher; Sharp, Zachary; Samuels, Kimberly; Ward, Dylan

2011-09-01

Simultaneous, real-time measurements of atmospheric water vapor mixing ratio and isotopic composition (δD and δ18O) were obtained using cavity ringdown spectroscopy on the arid Chajnantor Plateau in the subtropical Chilean Andes (elevation 5080 m or 550 hPa; latitude 23°S) during July and August 2010. The measurements show surface water vapor mixing ratio as low as 215 ppmv, δD values as low as -540‰, and δ18O values as low as -68‰, which are the lowest atmospheric water vapor δ values reported from Earth's surface. The results are consistent with previous measurements from the base of the tropical tropopause layer (TTL) and suggest large-scale subsidence of air masses from the upper troposphere to the Earth's surface. The range of measurements is consistent with condensation under conditions of ice supersaturation and mixing with moister air from the lower troposphere that has been processed through shallow convection. Diagnostics using reanalysis data show that the extreme aridity of the Chajnantor Plateau is controlled by condensation in the upper tropical troposphere.

Distributions of phytoplankton carbohydrate, protein and lipid in the world oceans from satellite ocean colour.

PubMed

Roy, Shovonlal

2018-06-01

Energy value of phytoplankton regulates the growth of higher trophic species, affecting the tropic balance and sustainability of marine food webs. Therefore, developing our capability to estimate and monitor, on a global scale, the concentrations of macromolecules that determine phytoplankton energy value, would be invaluable. Reported here are the first estimates of carbohydrate, protein, lipid, and overall energy value of phytoplankton in the world oceans, using ocean-colour data from satellites. The estimates are based on a novel bio-optical method that utilises satellite-derived bio-optical fingerprints of living phytoplankton combined with allometric relationships between phytoplankton cells and cellular macromolecular contents. The annually averaged phytoplankton energy value, per cubic metre of sub-surface ocean, varied from less than 0.1 kJ in subtropical gyres, to 0.5-1.0 kJ in parts of the equatorial, northern and southern latitudes, and rising to >10 kJ in certain coastal and optically complex waters. The annually averaged global stocks of carbohydrate, protein and lipid were 0.044, 0.17 and 0.108 gigatonnes, respectively, with monthly stocks highest in September and lowest in June, over 1997-2013. The fractional contributions of phytoplankton size classes e.g., picoplankton, nanoplankton and microplankton to surface concentrations and global stocks of macromolecules varied considerably across marine biomes classified as Longhurst provinces. Among these provinces, the highest annually averaged surface concentrations of carbohydrate, protein, and lipid were in North-East Atlantic Coastal Shelves, whereas, the lowest concentration of carbohydrate or lipid were in North Atlantic Tropical Gyral, and that of protein was in North Pacific Subtropical Gyre West. The regional accuracy of the estimates and their sensitivity to satellite inputs are quantified from the bio-optical model, which show promise for possible operational monitoring of phytoplankton energy value from satellite ocean colour. Adequate in situ measurements of macromolecules and improved retrievals of inherent optical properties from high-resolution satellite images, would be required to validate these estimates at local sites, and to further improve their accuracy in the world oceans.

26 CFR 1.897-9T - Treatment of certain interest in publicly traded corporations, definition of foreign person, and...

Code of Federal Regulations, 2011 CFR

2011-04-01

... regulation that, if and when adopted as a final regulation will be added as new paragraphs (c)(2)(iii)(B), (k... had a fair market value greater than the fair market value on that date of 5 percent of the regularly traded class of the corporation's stock with the lowest fair market value. However, if a non-regularly...

26 CFR 1.897-9T - Treatment of certain interest in publicly traded corporations, definition of foreign person, and...

Code of Federal Regulations, 2013 CFR

2013-04-01

... dealers making a market in such interests. A broker or dealer makes a market in a class of interests only... had a fair market value greater than the fair market value on that date of 5 percent of the regularly traded class of the corporation's stock with the lowest fair market value. However, if a non-regularly...

26 CFR 1.897-9T - Treatment of certain interest in publicly traded corporations, definition of foreign person, and...

Code of Federal Regulations, 2014 CFR

2014-04-01

... dealers making a market in such interests. A broker or dealer makes a market in a class of interests only... had a fair market value greater than the fair market value on that date of 5 percent of the regularly traded class of the corporation's stock with the lowest fair market value. However, if a non-regularly...

26 CFR 1.897-9T - Treatment of certain interest in publicly traded corporations, definition of foreign person, and...

Code of Federal Regulations, 2012 CFR

2012-04-01

... dealers making a market in such interests. A broker or dealer makes a market in a class of interests only... had a fair market value greater than the fair market value on that date of 5 percent of the regularly traded class of the corporation's stock with the lowest fair market value. However, if a non-regularly...

[Impact on prevalence of schitosomiasis after runs of Three Gorges Reservoir Project in the section of Anhui province].

PubMed

Zhang, Shiqing; Wang, Tianping; He, Jiachang; Li, Huazhong; Tian, Xuegen; Gao, Fenghua

2015-07-01

To investigate the changes of water level and the distribution of snails in Anhui province before and after runs of the Three Gorges Reservoir Project, and to determine the relationship between the two factors and schistosomiasis transmission. The hydrologic data of Datong hydrologic station and the data of snail status and schistosomiasis morbidity in Anhui Province were collected. The data from 1991 to 2002 and 2003 to 2012 were considered as before and after the impoundment of the Three Gorges Reservoir Project. Based on the prevalence of schistosomiasis, the cases of people and cattle were speculated, and the average infection rate of people and cattle were calculated. The t-test was used to compare the difference of snail area and the density of living snails before and after the impoundment of the Three Gorges Project. The pearson method was used to analyze the relationship between water level and snail area. The spearman method was used to analyze the relationship between the water level and the distribution of snails. From 1991 to 2012, the range of the highest water level, the lowest water level, the difference between the highest and lowest water level, the mean in the abundant water seasons, the mean in the dry water seasons, and the difference between the abundant water seasons and the dry water seasons was 11.40-16.30, 3.68-5.20, 6.70-12.12, 9.92-14.40, 4.77-7.64 and 4.13-8.93 m, respectively. The snail areas was (28 613 ± 362) hm² and (29 477 ± 918) hm² (t = -3.00, P = 0.007), the density of living snails was 1.51 (1.15-2.43) and 0.43 (0.29-1.10) snails/0.11 m² (H = 4.28, P < 0.001) before and after the impoundment of the Three Gorges Project, respectively. The average infection rate of people and cattle was 1.68% (99 482/5 935 147) and 4.62% (13 923/3 011 33), and the average number of acute schistosomiasis cases was 328, before the impoundment of the Three Gorges Project; 0.60% (39 747/6 649 380), 1.65% (1 291/783 224) and 71 after the impoundment of the Three Gorges Reservoir Project, respectively. The snail areas had negative correlation with the highest water level, the difference between the highest and lowest water level, the mean in the abundant water seasons (r value was -0.514, -0.509 and -0.477; P value was 0.014, 0.015 and 0.025, respectively). The infection rate of people had positive correlation with the highest water level, the difference between the highest and lowest water level, the mean in the abundant water seasons (r value was 0.532, 0.587 and 0.446; P value was 0.011, 0.004 and 0.038, respectively). The infection rate of cattle had positive correlation with the highest water level, the difference between the highest and lowest water level (r value was 0.507 and 0.553; P value was 0.016 and 0.008, respectively). The number of acute schistosomiasis cases had positive correlation with the highest water level, the difference between the highest and lowest water level (r value was 0.481 and 0.486; P value was 0.023 and 0.022, respectively). Following the runs of the Three Gorges Reservoir Project, the change of water level in the section of Anhui Province affected the distribution of snails and the infection of people and cattle to some extent. The snail areas showed an upward trend, and the density of living snails, the infection rate of people and cattle showed a downward trend. The runs of Three Gorges Reservoir Project has certain role to reduce flood and helpful for schistosomiasis control.

Anthrax and the geochemistry of soils in the contiguous United States

USGS Publications Warehouse

Griffin, Dale W.; Silvestri, Erin E.; Bowling, Charlena Y.; Boe, Timothy; Smith, David B.; Nichols, Tonya L.

2014-01-01

Soil geochemical data from sample sites in counties that reported occurrences of anthrax in wildlife and livestock since 2000 were evaluated against counties within the same states (MN, MT, ND, NV, OR, SD and TX) that did not report occurrences. These data identified the elements, calcium (Ca), manganese (Mn), phosphorus (P) and strontium (Sr), as having statistically significant differences in concentrations between county type (anthrax occurrence versus no occurrence). Tentative threshold values of the lowest concentrations of each of these elements (Ca = 0.43 wt %, Mn = 142 mg/kg, P = 180 mg/kg and Sr = 51 mg/kg) and average concentrations (Ca = 1.3 wt %, Mn = 463 mg/kg, P = 580 mg/kg and Sr = 170 mg/kg) were identified from anthrax-positive counties as prospective investigative tools in determining whether an outbreak had “potential” or was “likely” at any given geographic location in the contiguous United States.

Measuring Uranium Decay Rates for Advancement of Nuclear Forensics and Geochronology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parsons-Davis, Tashi

Radioisotopic dating techniques are highly valuable tools for understanding the history of physical and chemical processes in materials related to planetary sciences and nuclear forensics, and rely on accurate knowledge of decay constants and their uncertainties. The decay constants of U-238 and U-235 are particularly important to Earth science, and often the measured values with lowest reported uncertainties are applied, although they have not been independently verified with similar precision. New direct measurements of the decay constants of U-238, Th-234, U-235, and U-234 were completed, using a range of analytical approaches. An overarching goal of the project was to ensuremore » the quality of results, including metrological traceability to facilitate implementation across diverse disciplines. This report presents preliminary results of these experiments, as a few final measurements and calculations are still in progress.« less

Electron transfer flavoprotein deficiency: functional and molecular aspects.

PubMed

Schiff, Manuel; Froissart, Roseline; Olsen, Rikke K J; Acquaviva, Cécile; Vianey-Saban, Christine

2006-06-01

Multiple acyl-CoA dehydrogenase deficiency (MADD) is a recessively inherited metabolic disorder that can be due to a deficiency of electron transfer flavoprotein (ETF) or its dehydrogenase (ETF-ubiquinone oxidoreductase). ETF is a mitochondrial matrix protein consisting of alpha- (30kDa) and beta- (28kDa) subunits encoded by the ETFA and ETFB genes, respectively. In the present study, we have analysed tissue samples from 16 unrelated patients with ETF deficiency, and we report the results of ETF activity, Western blot analysis and mutation analysis. The ETF assay provides a reliable diagnostic tool to confirm ETF deficiency in patients suspected to suffer from MADD. Activity ranged from less than 1 to 16% of controls with the most severely affected patients disclosing the lowest activity values. The majority of patients had mutations in the ETFA gene while only two of them harboured mutations in the ETFB gene. Nine novel disease-causing ETF mutations are reported.

A comparison of career satisfaction amongst dental healthcare professionals across three health care systems: Comparison of data from the United Kingdom, New Zealand and Trinidad & Tobago

PubMed Central

Naidu, Rahul; Newton, J Tim; Ayers, Katie

2006-01-01

Background The aim of this study was to compare the expressed levels of career satisfaction of three groups of comparable dental healthcare professionals, working in Trinidad, the United Kingdom and New Zealand. Methods Three questionnaire surveys were carried out of comparable dental healthcare professionals. Dental nurses in Trinidad and dental therapists in the UK and New Zealand. Questionnaires were sent to all registered dental nurses or dental therapists. Results Career satisfaction was lowest amongst Dental Therapists working in Trinidad and Tobago. Approximately 59% of the Therapists working in New Zealand reported stated that they felt they were not a valued member of the dental team, the corresponding proportion in the United Kingdom was 32%, and for Trinidad 39%. Conclusion Dental therapists working in different healthcare systems report different levels of satisfaction with their career. PMID:16536870

Internalization of values and self-esteem among Brazilian teenagers from authoritative, indulgent, authoritarian, and neglectful homes.

PubMed

Martínez, Isabel; García, José Fernando

2008-01-01

The relation between parenting styles and adolescent outcomes was analyzed in a sample of 1,198 15-18-year-old Brazilians. The adolescents were classified into 1 of 4 groups (Authoritative, Authoritarian, Indulgent, and Neglectful) on the basis of their own ratings of their parents on two dimensions: Acceptance/ Involvement and Strictness/Imposition. The adolescents were then contrasted along two different outcomes: (1) priority given to Schwartz Self-transcendence and Conservation values, and (2) level of Self-esteem (appraised in 5 domains: Academic, Social, Emotional, Family, and Physical). Results showed that Authoritative and Indulgent parenting is associated with the highest internalization of Self-Transcendence and Conservation values of teenagers, whereas Authoritarian parenting is associated with the lowest. On the other hand, adolescents with Indulgent parents have equal or higher levels of Self-esteem than adolescents with Authoritative parents, while adolescents raised in Authoritarian and Neglectful homes have the lowest scores in Self-Esteem.

Finite element analysis to compare complete denture and implant-retained overdentures with different attachment systems.

PubMed

Barão, Valentim Adelino Ricardo; Assunção, Wirley Gonçalves; Tabata, Lucas Fernando; Delben, Juliana Aparecida; Gomes, Erica Alves; de Sousa, Edson Antonio Capello; Rocha, Eduardo Passos

2009-07-01

This finite element analysis compared stress distribution on complete dentures and implant-retained overdentures with different attachment systems. Four models of edentulous mandible were constructed: group A (control), complete denture; group B, overdenture retained by 2 splinted implants with bar-clip system; group C, overdenture retained by 2 unsplinted implants with o'ring system; and group D, overdenture retained by 2 splinted implants with bar-clip and 2 distally placed o'ring system. Evaluation was performed on Ansys software, with 100-N vertical load applied on central incisive teeth. The lowest maximum general stress value (in megapascal) was observed in group A (64.305) followed by groups C (119.006), D (258.650), and B (349.873). The same trend occurred in supporting tissues with the highest stress value for cortical bone. Unsplinted implants associated with the o'ring attachment system showed the lowest maximum stress values among all overdenture groups. Furthermore, o'ring system also improved stress distribution when associated with bar-clip system.

Large Calcium Isotopic Variation in Peridotitic Xenoliths from North China Craton

NASA Astrophysics Data System (ADS)

Huang, S.; Zhao, X.; Zhang, Z.

2016-12-01

Calcium is the fifth most abundant element in the Earth. The Ca isotopic composition of the Earth is important in many aspects, ranging from tracing the Ca cycle on the Earth to comparing the Earth to other terrestrial planets. There is large mass-dependent Ca isotopic variation, measured as δ44/40Ca relative to a standard sample, in terrestrial igneous rocks: about 2 per mil in silicate rocks, compared to 3 per mil in carbonates. Therefore, a good understanding of the Ca isotopic variation in igneous rocks is necessary. Here we report Ca isotopic data on a series of peridotitic xenoliths from North China Craton (NCC). There is about 1 per mil δ44/40Ca variation in these NCC peridotites: The highest δ44/40Ca is close to typical mantle values, and the lowest δ44/40Ca is found in an Fe-rich peridotite, -1.13 relative to normal mantle (or -0.08 on the SRM 915a scale). This represents the lowest δ44/40Ca value ever reported for igneous rocks. Combined with published Fe isotopic data on the same samples, our data show a positive linear correlation between δ44/40Ca and δ57/54Fe in NCC peridotites. This trend is inconsistent with mixing a low-δ44/40Ca and -δ57/54Fe sedimentary component with a normal mantle component. Rather, it is best explained as the result of kinetic isotopic effect caused by melt-peridotite reaction on a time scale of several hundreds of years. In detail, basaltic melt reacts with peridotite, replaces orthopyroxene with clinopyroxene, and increases the Fo number of olivine. Consistent with this interpretation, our on-going Mg isotopic study shows that low-δ44/40Ca and -δ57/54Fe NCC peridotites also have heavier Mg isotopes compared to normal mantle. Our study shows that mantle metasomatism plays an important role generating stable isotopic variations within the Earth's mantle.

log gf values for astrophysically important transitions Fe II

NASA Astrophysics Data System (ADS)

Deb, N. C.; Hibbert, A.

2014-01-01

Aims: In a recent measurement, Meléndez & Barbuy (2009, A&A, 497, 611) report accurate log gf values for 142 important astrophysical lines with wavelengths in the range 4000 Å to 8000 Å. Their results include both solar and laboratory measurements. In this paper, we describe a theoretical study of these lines. Methods: The CIV3 structure codes, combined with our "fine-tuning" extrapolation process, are used to undertake a large-scale CI calculation involving the lowest 262 fine-structure levels belonging to the 3d64s, 3d7, 3d54s2, 3d64p, and 3d54s4p configurations. Results: We find that many of the 142 transitions are very weak intercombination lines. Other transitions are weak because the dominant configurations in the two levels differ by two orbitals. Conclusions: The comparison between our log gf values and the experimental values generally shows good agreement for most of these transitions, with our theoretical values agreeing slightly more closely with the solar than with the laboratory measurements. A detailed analysis of the small number of transitions for which the agreement between theory and experiment is not as good shows that such disagreements largely arise from severe cancellation due to CI mixing.

Exploring factors that might influence primary-care provider discussion of and recommendation for prostate and colon cancer screening.

PubMed

Kistler, Christine E; Vu, Maihan; Sutkowi-Hemstreet, Anne; Gizlice, Ziya; Harris, Russell P; Brewer, Noel T; Lewis, Carmen L; Dolor, Rowena J; Barclay, Colleen; Sheridan, Stacey L

2018-01-01

Primary-care providers may contribute to the use of low-value cancer screening. We sought to examine circumstances under which primary-care providers would discuss and recommend two types of cancer screening services across a spectrum of net benefit and other factors known to influence screening. This was a cross sectional survey of 126 primary-care providers in 24 primary-care clinics in the US. Participants completed surveys with two hypothetical screening scenarios for prostate or colorectal cancer (CRC). Patients in the scenarios varied by age and screening-request status. For each scenario, providers indicated whether they would discuss and recommend screening. Providers also reported on their screening attitudes and the influence of other factors known to affect screening (short patient visits, worry about lawsuits, clinical reminders/performance measures, and screening guidelines). We examined associations between providers' attitudes and their screening recommendations for hypothetical 90-year-olds (the lowest-value screening). Providers reported they would discuss cancer screening more often than they would recommend it ( P <0.001). More providers would discuss and recommend screening for CRC than prostate cancer ( P <0.001), for younger than older patients ( P <0.001), and when the patient requested it than when not ( P <0.001). For a 90-year-old patient, every point increase in cancer-specific screening attitude increased the likelihood of a screening recommendation (30% for prostate cancer and 30% for CRC). While most providers' reported practice patterns aligned with net benefit, some providers would discuss and recommend low-value cancer screening, particularly when faced with a patient request. More work appears to be needed to help providers to discuss and recommend screening that aligns with value.

Exploring factors that might influence primary-care provider discussion of and recommendation for prostate and colon cancer screening

PubMed Central

Kistler, Christine E; Vu, Maihan; Sutkowi-Hemstreet, Anne; Gizlice, Ziya; Harris, Russell P; Brewer, Noel T; Lewis, Carmen L; Dolor, Rowena J; Barclay, Colleen; Sheridan, Stacey L

2018-01-01

Background Primary-care providers may contribute to the use of low-value cancer screening. Objective We sought to examine circumstances under which primary-care providers would discuss and recommend two types of cancer screening services across a spectrum of net benefit and other factors known to influence screening. Patients and methods This was a cross sectional survey of 126 primary-care providers in 24 primary-care clinics in the US. Participants completed surveys with two hypothetical screening scenarios for prostate or colorectal cancer (CRC). Patients in the scenarios varied by age and screening-request status. For each scenario, providers indicated whether they would discuss and recommend screening. Providers also reported on their screening attitudes and the influence of other factors known to affect screening (short patient visits, worry about lawsuits, clinical reminders/performance measures, and screening guidelines). We examined associations between providers’ attitudes and their screening recommendations for hypothetical 90-year-olds (the lowest-value screening). Results Providers reported they would discuss cancer screening more often than they would recommend it (P<0.001). More providers would discuss and recommend screening for CRC than prostate cancer (P<0.001), for younger than older patients (P<0.001), and when the patient requested it than when not (P<0.001). For a 90-year-old patient, every point increase in cancer-specific screening attitude increased the likelihood of a screening recommendation (30% for prostate cancer and 30% for CRC). Discussion While most providers’ reported practice patterns aligned with net benefit, some providers would discuss and recommend low-value cancer screening, particularly when faced with a patient request. Conclusion More work appears to be needed to help providers to discuss and recommend screening that aligns with value. PMID:29844698

The lowest ionization potentials of Al2

NASA Technical Reports Server (NTRS)

Bauschlicher, Charles W., Jr.; Barnes, Leslie A.; Taylor, Peter R.

1988-01-01

Potential curves for the lowest two electronic states (X 2 sigma g + and A 2 pi u) of Al2(+) were computed using complete active space SCF/multireference CI wave functions and large Gaussian basis sets. The lowest observable vertical ionization potential (to Al2(+) X 2 sigma g +) of the Al2 X 3 pi u ground state is calculated to occur around 6.1 eV, in excellent agreement with the experimental range of 6.0 to 6.42 eV obtained in recent cluster ionization studies by Cox and co-workers. The second vertical ionization potential (to Al2(+) A 2 pi u) occurs near 6.4 eV, also within the experimental range. The adiabatic IP of 5.90 eV is in good agreement with the value of 5.8 to 6.1 eV deduced by Hanley and co-workers from the difference in thresholds between collision induced dissociation processes of Al3(+). The computed IP values are somewhat larger than those deduced from branching ratios in cluster fragmentation experiments by Jarrold and co-workers. The observation of an ionization threshold below 6.42 eV is shown to be incompatible with an Al2 ground electronic state assignment of 3 sigma g -, but the separation between the two lowest states of Al2 is so small that it is likely that both are populated in the experiments, so that this does not provide unambiguous support for the recent theoretical assignment of the ground state as 3 pi u.

Sub-Micrometer Zeolite Films on Gold-Coated Silicon Wafers with Single-Crystal-Like Dielectric Constant and Elastic Modulus

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tiriolo, Raffaele; Rangnekar, Neel; Zhang, Han

A low-temperature synthesis coupled with mild activation produces zeolite films exhibiting low dielectric constant (low-k) matching the theoretically predicted and experimentally measured values for single crystals. This synthesis and activation method allows for the fabrication of a device consisting of a b-oriented film of the pure-silica zeolite MFI (silicalite-1) supported on a gold-coated silicon wafer. The zeolite seeds are assembled by a manual assembly process and subjected to optimized secondary growth conditions that do not cause corrosion of the gold underlayer, while strongly promoting in-plane growth. The traditional calcination process is replaced with a non-thermal photochemical activation to ensure preservationmore » of an intact gold layer. The dielectric constant (k), obtained through measurement of electrical capacitance in a metal-insulator-metal configuration, highlights the ultralow k approximate to 1.7 of the synthetized films, which is among the lowest values reported for an MFI film. There is large improvement in elastic modulus of the film (E approximate to 54 GPa) over previous reports, potentially allowing for integration into silicon wafer processing technology.« less

On-demand generation of background-free single photons from a solid-state source

NASA Astrophysics Data System (ADS)

Schweickert, Lucas; Jöns, Klaus D.; Zeuner, Katharina D.; Covre da Silva, Saimon Filipe; Huang, Huiying; Lettner, Thomas; Reindl, Marcus; Zichi, Julien; Trotta, Rinaldo; Rastelli, Armando; Zwiller, Val

2018-02-01

True on-demand high-repetition-rate single-photon sources are highly sought after for quantum information processing applications. However, any coherently driven two-level quantum system suffers from a finite re-excitation probability under pulsed excitation, causing undesirable multi-photon emission. Here, we present a solid-state source of on-demand single photons yielding a raw second-order coherence of g(2 )(0 )=(7.5 ±1.6 )×10-5 without any background subtraction or data processing. To this date, this is the lowest value of g(2 )(0 ) reported for any single-photon source even compared to the previously reported best background subtracted values. We achieve this result on GaAs/AlGaAs quantum dots embedded in a low-Q planar cavity by employing (i) a two-photon excitation process and (ii) a filtering and detection setup featuring two superconducting single-photon detectors with ultralow dark-count rates of (0.0056 ±0.0007 ) s-1 and (0.017 ±0.001 ) s-1, respectively. Re-excitation processes are dramatically suppressed by (i), while (ii) removes false coincidences resulting in a negligibly low noise floor.

Lowest-energy cage structures of medium-sized ( ZnO )n clusters with n = 15 - 24

NASA Astrophysics Data System (ADS)

Tang, Lingli; Sai, Linwei; Zhao, Jijun; Qiu, Ruifeng

2015-01-01

Fullerene-like cage structures of medium-sized ( ZnO )n clusters with n = 15 - 24 were generated by spiral algorithm and optimized using density functional theory calculations. Most of these lowest-energy cage structures contain only four-membered and six-membered rings, whereas eight-membered rings were found in the lowest-energy cages of ( ZnO )n (n = 19, 20, 23, 24). Our best cage configurations either reproduce or prevail the previously reported ones. The size-dependent electronic properties were also discussed.

Lowest-energy cage structures of medium-sized (ZnO){sub n} clusters with n = 15 − 24

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tang, Lingli; Sai, Linwei; Zhao, Jijun, E-mail: zhaojj@dlut.edu.cn

2015-01-22

Fullerene-like cage structures of medium-sized (ZnO){sub n} clusters with n = 15 − 24 were generated by spiral algorithm and optimized using density functional theory calculations. Most of these lowest-energy cage structures contain only four-membered and six-membered rings, whereas eight-membered rings were found in the lowest-energy cages of (ZnO){sub n} (n = 19, 20, 23, 24). Our best cage configurations either reproduce or prevail the previously reported ones. The size-dependent electronic properties were also discussed.

The relationship between airborne small ions and particles in urban environments

NASA Astrophysics Data System (ADS)

Ling, Xuan; Jayaratne, Rohan; Morawska, Lidia

2013-11-01

Ions play an important role in affecting climate and particle formation in the atmosphere. Small ions rapidly attach to particles in the air and, therefore, studies have shown that they are suppressed in polluted environments. Urban environments, in particular, are dominated by motor vehicle emissions and, since motor vehicles are a source of both particles and small ions, the relationship between these two parameters is not well known. In order to gain a better understanding of this relationship, an intensive campaign was undertaken where particles and small ions of both signs were monitored over two week periods at each of three sites A, B and C that were affected to varying degrees by vehicle emissions. Site A was close to a major road and reported the highest particle number and lowest small ion concentrations. Precursors from motor vehicle emissions gave rise to clear particle formation events on five days and, on each day this was accompanied by a suppression of small ions. Observations at Site B, which was located within the urban airshed, though not adjacent to motor traffic, showed particle enhancement but no formation events. Site C was a clean site, away from urban sources. This site reported the lowest particle number and highest small ion concentration. The positive small ion concentration was 10%-40% higher than the corresponding negative value at all sites. These results confirm previous findings that there is a clear inverse relationship between small ions and particles in urban environments dominated by motor vehicle emissions.

Aquatic life at high altitude: respiratory adaptations in the Lake Titicaca frog, Telmatobius culeus.

PubMed

Hutchison, V H; Haines, H B; Engbretson, G

1976-07-01

Telmatobius culeus has a combination of behavioral, morphological and physiological adaptations which allows an aquatic life in cool (10 degrees C) O2-saturated (at 100 mm Hg) waters at high altitude (3812 m). The skin surgace area is increased by pronounced folds and the cutaneous capillaries penetrate to the outer layers of the skin. The erythrocyte volume (394 mu3) is the smallest reported for amphibians. The P50 (15.6 at ph 7.65 and 10 degrees C) is the lowest, and the erythrocyte count (729 - 103/mm3) the highest for an anuran. The O2 capacity (11.7 vol%), hemoglobin (8.1 g/100 ml), hemoglobin concentration (0.281 pg/mu3) and hematocrit (27.9%) measured at 18 degrees C and 3800 m are all elevated in comparison with most amphibians. The O2 dissociation curve is sigmoid (n = 2), the Bohr factor is small (deltalog P50/deltapH = -0.30) and the buffering capacity (-8.9 m M HCO3 - 1-1) is typical for an aquatic amphibian. The metabolic rate (14.1 mul -g-1-h-u) is the lowest reported for a frog and among amphibians only the giant salamanders (Amphiuma, Necturus and Siren) have lower values. If prevent from surfacing in hypoxic waters, the frogs ventilate the skin by "bobbing" behavior; if allowed to surface, they will ventilate the small lungs and the metabolic rate increases to 23 mul-g-1-h-1.

Quality of reporting in oncology phase II trials: A 5-year assessment through systematic review.

PubMed

Langrand-Escure, Julien; Rivoirard, Romain; Oriol, Mathieu; Tinquaut, Fabien; Rancoule, Chloé; Chauvin, Frank; Magné, Nicolas; Bourmaud, Aurélie

2017-01-01

Phase II clinical trials are a cornerstone of the development in experimental treatments They work as a "filter" for phase III trials confirmation. Surprisingly the attrition ratio in Phase III trials in oncology is significantly higher than in any other medical specialty. This suggests phase II trials in oncology fail to achieve their goal. Objective The present study aims at estimating the quality of reporting in published oncology phase II clinical trials. A literature review was conducted among all phase II and phase II/III clinical trials published during a 5-year period (2010-2015). All articles electronically published by three randomly-selected oncology journals with Impact-Factors>4 were included: Journal of Clinical Oncology, Annals of Oncology and British Journal of Cancer. Quality of reporting was assessed using the Key Methodological Score. 557 articles were included. 315 trials were single-arm studies (56.6%), 193 (34.6%) were randomized and 49 (8.8%) were non-randomized multiple-arm studies. The Methodological Score was equal to 0 (lowest level), 1, 2, 3 (highest level) respectively for 22 (3.9%), 119 (21.4%), 270 (48.5%) and 146 (26.2%) articles. The primary end point is almost systematically reported (90.5%), while sample size calculation is missing in 66% of the articles. 3 variables were independently associated with reporting of a high standard: presence of statistical design (p-value <0.001), multicenter trial (p-value = 0.012), per-protocol analysis (p-value <0.001). Screening was mainly performed by a sole author. The Key Methodological Score was based on only 3 items, making grey zones difficult to translate. This literature review highlights the existence of gaps concerning the quality of reporting. It therefore raised the question of the suitability of the methodology as well as the quality of these trials, reporting being incomplete in the corresponding articles.

Quality of reporting in oncology phase II trials: A 5-year assessment through systematic review

PubMed Central

Langrand-Escure, Julien; Rivoirard, Romain; Oriol, Mathieu; Tinquaut, Fabien; Rancoule, Chloé; Chauvin, Frank; Magné, Nicolas; Bourmaud, Aurélie

2017-01-01

Background Phase II clinical trials are a cornerstone of the development in experimental treatments They work as a "filter" for phase III trials confirmation. Surprisingly the attrition ratio in Phase III trials in oncology is significantly higher than in any other medical specialty. This suggests phase II trials in oncology fail to achieve their goal. Objective The present study aims at estimating the quality of reporting in published oncology phase II clinical trials. Data sources A literature review was conducted among all phase II and phase II/III clinical trials published during a 5-year period (2010–2015). Study eligibility criteria All articles electronically published by three randomly-selected oncology journals with Impact-Factors>4 were included: Journal of Clinical Oncology, Annals of Oncology and British Journal of Cancer. Intervention Quality of reporting was assessed using the Key Methodological Score. Results 557 articles were included. 315 trials were single-arm studies (56.6%), 193 (34.6%) were randomized and 49 (8.8%) were non-randomized multiple-arm studies. The Methodological Score was equal to 0 (lowest level), 1, 2, 3 (highest level) respectively for 22 (3.9%), 119 (21.4%), 270 (48.5%) and 146 (26.2%) articles. The primary end point is almost systematically reported (90.5%), while sample size calculation is missing in 66% of the articles. 3 variables were independently associated with reporting of a high standard: presence of statistical design (p-value <0.001), multicenter trial (p-value = 0.012), per-protocol analysis (p-value <0.001). Limitations Screening was mainly performed by a sole author. The Key Methodological Score was based on only 3 items, making grey zones difficult to translate. Conclusions & implications of key findings This literature review highlights the existence of gaps concerning the quality of reporting. It therefore raised the question of the suitability of the methodology as well as the quality of these trials, reporting being incomplete in the corresponding articles. PMID:29216190

Comparative evaluation of antiproliferative effects of Brazilian green propolis, its main source Baccharis dracunculifolia, and their major constituents artepillin C and baccharin.

PubMed

de Oliveira, Pollyanna Francielli; de Souza Lima, Ildercílio Mota; Munari, Carla Carolina; Bastos, Jairo Kenupp; da Silva Filho, Ademar Alves; Tavares, Denise Crispim

2014-04-01

This study evaluated the antiproliferative activity of the Brazilian green propolis and Baccharis dracunculifolia extracts and their major compounds artepillin C and baccharin in different tumor cell lines. The lowest IC50 values observed for Brazilian green propolis and B. dracunculifolia extracts were 41.0 ± 4.5 µg/mL for U343 and 44.9 ± 7.1 µg/mL for HepG2, respectively. Regarding artepillin C and baccharin, the lowest IC50 values were 20.1 ± 2.9 for U343 and 13.0 ± 1.5 µg/mL for B16F10, respectively. For the association of artepillin C plus baccharin, the lowest IC50 result was 35.2 ± 0.5 µg/mL for B16F10. Artepillin C and baccharin were more cytotoxic than both Brazilian green propolis and B. dracunculifolia extracts. No additive or synergistic effect was observed for the association of artepillin C plus baccharin. Georg Thieme Verlag KG Stuttgart · New York.

RADIATION STABILITY OF ORGANIC LIQUIDS. Semi-Annual Report No. 4 for July 1 to December 31, 1958

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wagner, R.M.; Towle, L.H.

1959-01-01

0 @ 4 2 7 1 8 3 7 1 7 6 TBP from 0 to 100 were irradiated with electrons to 300 to 400 whr/liter. The G(total acid) values obtained indicated that, from 0 to 60 wt, % TBP, the acid produc tion rate is proportional to wt, % TBP; above 60 wt, % TBP the acid production rate is lower. Normalized total acid G values, obtained by partition of the dose on a basis of wt, % TBP, ranged from 2.31 to 3.52. Seven TBP-Amsco solutions, ranging from 5 to 60 wt. % TBP, and samples of puremore » TBP and pure dibutyl phenylphosphorate (DBPP) were irradiated to 400 whr/liter, Five compositions of TBP, DBPP, Amsco, and tetralin were irradiated to 200 whr/liter. The amount of radiationinduced unsataration was measured for each of the above samples. The data indicated that unsaturation varied inversely with wt. % TBP. The DBPP exerted a small protective effect, as did tetralin, in reducing radiation damage to the Amsco. Diethyl carbonate, irradiated to 392 whr/liter, had a G(gas) value of 4.86, a--G (target destruction) value of 5.50, and a --G /sub M/(polymer) value of 2.80. Diethyl carbonate, after irradiation, extracts U better than virgin material and strips equally as well. The irradiated diethyl carbonate exhibited no difference from virgin material in emulsification tendency. Dibutyl phenylphosphorate-Amsco systems, at dose levels of either 200 or 400 whr/liter, showed that acid production is about proportioral to wt. % DBPP. Studies of DBPP-Amsco-tetralin systems at 200 whr/ liter indicated that tetralin is more acceptable than decalin for enhancing the solubility of the DBPP-uranium complex in Amsco, thus suppressing third-phase phenomena. Tetralin also reduced acid production from DBPP under irradiation. Tributyl phosphate, dibutyl phosphoric acid, and di-(2- ethylhexyl) phosphoric acid were irradiated in the pure state to 300 whr/liter. The G(gas) values were 1.9, 3.3, and 3.1, respectively, and the G(total acid) values were 2.3, 2.1, and 1.2. The--G values for target converted to polymer were 0.22 for the DBP, and 0.32 for the D2EHP. Tri-n-octyl phosphine oxide was irradiated in the pure state to 400 whr/liter. The G(gas) value of 1.82 was comparable to a value of 1.45 found previously at 2040 whr/1iter. Values of --G/ sub M/ for target and polymer were approximately double the values previously found at 2040 whr/ liter. Amines, including tri-lauryl amine, n-benzyl heptadecyl amine, tri-iso-octyl amine, Primene JM-T, and tri-oetyl-decyl-t-amine (Alamine) were irradiated to either 200- or 400-whr/liter doses. The Primene produced the lowest --G (polymer) value, (1.50) and the Alamine produced the highest -- G/sub M/(total target destroyed) value (3.49). An Alamine-tridecanol- Amsconitric acid system yielded the lowest G(gas) value (1.89) while the corresponding tri-lauryl amine system produced the highest (3.12). The most extensive emulsification occurred with the 0.5M tri-lauryl amtne-Amscotridecanol system while the n-benzyl heptadecyl amine system exhtbited the lowest emulsification tendency, The most efficient U extractant system observed was the Alamine-Amsco-tridecanol-nitric acid composition, at the 0.5M-Alamine level. A comparison was made of the quantity and composition of material removed from irradiated TBP-Amsco by various scrubbing media. A single scrub with 2M NaOH appears four times more efftcient than does a single scrub with satarated CaOH in removing acidic radiolysis products. The emulsification tendency of the scrubbed organic appears to increase with the quantity of acidic radiolysis products removed. Radiolysis products other than those of acidic natare (polymer) are apparently not removed by the scrubbing media investigated in this study. An ir« less

Exploring the influence of texture and composition on the thermal transport properties of mudstones

NASA Astrophysics Data System (ADS)

Kenderes, S. M.; Hofmeister, A. M.; Merriman, J. D.; Whittington, A. G.

2017-12-01

The thermal history of sedimentary basins depends strongly on the thermal transport properties of the rocks within the basin. Mudstones are compositionally diverse, varying both chemically and with modal mineralogy, which are known to affect the thermal transport properties of earth materials. To explore the influence of composition and texture on the thermal transport properties of mudstones, we have measured the thermal diffusivity (D) and isobaric heat capacity (CP) of 12 mudstones using the contact-free laser flash analysis (LFA) and differential scanning calorimetry (DSC). At 20°C, D values of the shales range from 0.318 to 1.214 mm2·s-1 and CP values range from 799 to 918 J·kg-1·°C-1 and at 300°C, D values range from 0.227 to 0.582 mm2·s-1 and CP values range from 1095 to 1344 J·kg-1·°C-1. The mudstones with the highest D values, and lowest CP values are green micaceous or calcareous siltstones respectively, whereas the mudstones with the lowest D values, and highest CP values are black, claystones with 9% organic carbon. This suggests that organic carbon content and, to a lesser extent, the grainsize influence the thermal transport properties of these rocks. The lower D values and higher CP values cause organic rich claystones to absorb and transmit heat differently than other types of mudstones. This is especially true at lower temperatures, where the difference in D values is much greater than at higher temperatures. Additionally, when compared to other sedimentary rocks, shales generally have lower D values and higher CP values. These results also highlight the necessity of using rock type specific values in heat transport numerical models.

Mercury conversion processes in Amazon soils evaluated by thermodesorption analysis.

PubMed

do Valle, Cláudia M; Santana, Genilson P; Windmöller, Cláudia C

2006-12-01

This paper reports on the speciation study and the Hg redox behavior in Amazon soils not influenced by gold mining and collected near Manaus, AM, Brazil. The samples were incubated by adding Hg(0) and HgCl(2) to dry soil. Solid phase Hg speciation analysis was carried out using a Hg thermodesorption technique with the aim of distinguishing elemental Hg(0) from Hg(II) binding forms. In the first case, we observed the conversion of Hg(0) to Hg(II) binding forms in the range of 28-68% and a correlation between the percent of oxidation and OM content. Samples incubated with Hg(II) showed the formation of Hg(I) and/or Hg(0) in the range of 19-69%. The lowest values corresponded to the samples with the lowest clay contents. The kinetics of conversion of Hg(0) as well as HgCl(2) were roughly fitted to the two first order reactions, a fast one and a slow one. It was not possible to evaluate differences between sampling sites and types of soils, but the mean half-life of the first order reaction obtained by the addition of Hg(II) was slower (t(1/2)=365d) than the one obtained by the addition of Hg(0) (t(1/2)=148d). Previous studies have shown the predominance of organically bound Hg in these samples. Thus, the kinetic difference between Hg oxidation and reduction in combination with the efficient retention processes by OM may explain the high background values found in Amazon soils.

Dietary sodium intake and prevalence of overweight in adults.

PubMed

Song, Hong Ji; Cho, Young Gyu; Lee, Hae-Jeung

2013-05-01

There has been no convincing evidence for a direct relation between sodium intake and being overweight. Therefore, we investigated the independent relationship between overweight and sodium intake in human subjects. Of those aged 19 to 64 years who participated in the 4th Korea National Health and Nutrition Examination Survey, a total of 5955 participants (54% female) were included. Subjects were excluded if they reported unrealistic daily total energy intakes or intentional dietary changes, were pregnant, or were diagnosed with hypertension, diabetes, renal failure, liver cirrhosis, or thyroid disease. Overweight was defined as having a body mass index of 25 kg/m(2) or higher. Sodium intake was calculated from 24-h recall and categorized into quintiles. Multivariate logistic regression was used to test the relationship between sodium intake and being overweight. Compared to men in the lowest quintile, men in the 4th and 5th quintiles had an increased risk of being overweight with odds ratios (ORs) of 1.37 (95% confidence interval [CI], 1.02-1.82) and 1.67 (95% CI, 1.23-2.27) respectively, after adjusting for confounding factors including soft drink and energy intake. The P value for trend of ORs in each quintile for men was 0.0033. In women, compared to the lowest quintile, the highest quintile had an OR of 1.31(95% CI, 0.96-1.79) and showed a marginally significant trend towards increasing risk of being overweight (P value=.058). Our findings suggest an independent relationship between high sodium intake and an increased risk of being overweight in adults. Copyright © 2013 Elsevier Inc. All rights reserved.

Gamma-ray Transition Matrix Elements in ^21Na: First TIGRESS Radioactive Beam Experiment

NASA Astrophysics Data System (ADS)

Hackman, Greg

2007-04-01

Modern shell model calculations should be expected to reliably reproduce the properties of the deformed five-particle nucleus ^21Na. However the lowest-lying B(E2) value deduced from lifetime and mixing ratio measurements disagrees with models by an unacceptably large factor of two. To measure the B(E2) values directly, a beam of ^21Na at 1.7 MeV/u from the TRIUMF ISAC facility was directed upon a 0.5 mg/cm^2 ^natTi target. Gamma-ray yield in coincidence with inelastically scattered heavy ions was measured with two TIGRESS high energy- and position-resolution germanium detector units and the BAMBINO highly segmented silicon detector system. The result resolves the discrepancy between the shell model and prior measurements. This represents the first radioactive in-beam experiment with TIGRESS.

Influence of micellar calcium and phosphorus on rennet coagulation properties of cows milk.

PubMed

Malacarne, Massimo; Franceschi, Piero; Formaggioni, Paolo; Sandri, Sandro; Mariani, Primo; Summer, Andrea

2014-05-01

The main requirement for milk processed in most cheese typologies is its rennet coagulation ability. Despite the increasing number of studies, the causes for abnormal coagulation of milk are not fully understood. The aim of this study was to ascertain relationships between milk characteristics and its rennet coagulation ability, focusing on the influence of calcium (Ca) and phosphorus (P). Ca and P are essential constituents of the micelles. Micellar P can be present as part of colloidal calcium phosphate (inorganic-P) or covalently bound to caseins as phosphate groups (casein-P). Eighty one herd milk samples (SCC<400 000 cell/ml) were classified as Optimal (8), Suboptimal (39) Poor (29) and Non-coagulating milk (5), according to their rennet coagulation parameters as assessed by lactodynamographic test. Samples were analysed for their chemical composition (basic composition, protein fractions, minerals and salt equilibria), physicochemical parameters (pH and titratable acidity) and rheological properties. Optimal milk was characterised by the highest contents of major constituents, protein fractions and minerals, lowest content of chloride and highest values of titratable acidity. Non-coagulating milk was characterised by the highest values of pH and the lowest of titratable acidity. At micellar level, Optimal milk showed the highest values of colloidal Ca, casein-P and colloidal Mg (g/100 g casein), while Non-coagulating milk showed the lowest values. Interestingly, there was no statistical difference regarding the content of colloidal inorganic-P (g/100 g casein) between Optimal and Non-coagulating milks. Overall, high mineralisation of the micelle (expressed as g inorganic-P/100 g casein) positively affect its rennetability. However, excessive mineralisation could lead to a reduction of the phosphate groups (g casein-P/100 g casein) available for curd formation.

The effect of cutting parameters on the performance of ZTA-MgO cutting tool

NASA Astrophysics Data System (ADS)

Ali, A. M.; Hamidon, N. E.; Zaki, N. K. M.; Mokhtar, S.; Azhar, A. Z. A.; Bahar, R.; Ahmad, Z. A.

2018-01-01

The effect of cutting parameters on the performances of ZTA-MgO ceramic cutting tool investigated. The aim of this project is to discover the effect of cutting speed and feedrate on the performance of the ZTA-MgO cutting tool via wear and surface roughness measurement. CNC turning machining performed using the cutting speed, Vc range from 354 to 471 m/min and the feed rate, f 0.1, 0.3 and 0.5 mm/rev while the depth of cut, d is kept constant at 0.2 mm. The flank wear, crater wear, and chipping were measured accordingly using optical microscope, Matlab programming and SEM. Surface roughness of machined stainless steel 316L surface were measured using the surface roughness tester (Mitutoyo MTR097-8. The result showing the increment trend of flank wear with increment of cutting speed and feed rate with the lowest value of flank wear, 0.061 mm achieved at Vc = 354 m/min and f = 0.1 mm/rev while the highest flank wear is 0.480 mm at Vc = 471 m/min and f = 0.5 mm/rev. The increasing pattern also observed in the crater wear results. The lowest area of crater wear is 2.2736 mm2 at Vc = 354 m/min and f = 0.1 mm/rev while the highest value is 4.8524 mm2 at Vc = 471 m/min and f = 0.5 mm/rev. As for the surface roughness, the higher the cutting speed, the lower the average roughness (Ra) value. Cutting speed, Vc = 471 m/min with f = 0.1 mm/rev has the lowest value of Ra which is 0.72µm.

Development of water quality criteria and screening benchmarks for 2,4,6 trinitrotoluene

DOE Office of Scientific and Technical Information (OSTI.GOV)

Talmage, S.S.; Opresko, D.M.

1995-12-31

Munitions compounds and their degradation products are present at many Army Ammunition Plant Superfund sites. Neither Water Quality Criteria (WQC) for aquatic organisms nor safe soil levels for terrestrial plants and animals have been developed for munitions compounds including trinitrotoluene (TNT). Data are available for the calculation of an acute WQC for TNT according to US EPA guidelines but are insufficient to calculate a chronic criterion. However, available data can be used to determine a Secondary Chronic Value (SCV) and to determine lowest chronic values for fish and daphnids (used by EPA in the absence of criteria). Based on datamore » from eight genera of aquatic organisms, an acute WOC of 0.566 mg/L was calculated. Using available data, a SCV of 0.137 mg/L was calculated. Lowest chronic values for fish and for daphnids are 0.04 mg/L and 1.03 mg/L, respectively. The lowest concentration that affected the growth of aquatic plants was 1.0 mg/L. For terrestrial animals, data from studies of laboratory animals can be extrapolated to derive screening benchmarks in the same way in which human toxicity values are derived from laboratory animal data. For terrestrial animals, a no-observed-adverse-effect-level (NOAEL) for reproductive effects of 1.60 mg/kg/day was determined from a subchronic laboratory feeding study with rats. By scaling the test NOAEL on the basis of differences in body size, screening benchmarks were calculated for oral intake for selected mammalian wildlife species. Screening benchmarks were also derived for protection of benthic organisms in sediment, for soil invertebrates, and for terrestrial plants.« less

Multilevel modelling of somatotype components: the Portuguese sibling study on growth, fitness, lifestyle and health.

PubMed

Pereira, Sara; Katzmarzyk, Peter T; Gomes, Thayse Natacha; Souza, Michele; Chaves, Raquel N; Santos, Fernanda K Dos; Santos, Daniel; Hedeker, Donald; Maia, José A R

2017-06-01

Somatotype is a complex trait influenced by different genetic and environmental factors as well as by other covariates whose effects are still unclear. To (1) estimate siblings' resemblance in their general somatotype; (2) identify sib-pair (brother-brother (BB), sister-sister (SS), brother-sister (BS)) similarities in individual somatotype components; (3) examine the degree to which between and within variances differ among sib-ships; and (4) investigate the effects of physical activity (PA) and family socioeconomic status (SES) on these relationships. The sample comprises 1058 Portuguese siblings (538 females) aged 9-20 years. Somatotype was calculated using the Health-Carter method, while PA and SES information was obtained by questionnaire. Multi-level modelling was done in SuperMix software. Older subjects showed the lowest values for endomorphy and mesomorphy, but the highest values for ectomorphy; and more physically active subjects showed the highest values for mesomorphy. In general, the familiality of somatotype was moderate (ρ = 0.35). Same-sex siblings had the strongest resemblance (endomorphy: ρ SS > ρ BB > ρ BS ; mesomorphy: ρ BB = ρ SS > ρ BS ; ectomorphy: ρ BB > ρ SS > ρ BS ). For the ectomorphy and mesomorphy components, BS pairs showed the highest between sib-ship variance, but the lowest within sib-ship variance; while for endomorphy BS showed the lowest between and within sib-ship variances. These results highlight the significant familial effects on somatotype and the complexity of the role of familial resemblance in explaining variance in somatotypes.

A stochastic algorithm for global optimization and for best populations: A test case of side chains in proteins

PubMed Central

Glick, Meir; Rayan, Anwar; Goldblum, Amiram

2002-01-01

The problem of global optimization is pivotal in a variety of scientific fields. Here, we present a robust stochastic search method that is able to find the global minimum for a given cost function, as well as, in most cases, any number of best solutions for very large combinatorial “explosive” systems. The algorithm iteratively eliminates variable values that contribute consistently to the highest end of a cost function's spectrum of values for the full system. Values that have not been eliminated are retained for a full, exhaustive search, allowing the creation of an ordered population of best solutions, which includes the global minimum. We demonstrate the ability of the algorithm to explore the conformational space of side chains in eight proteins, with 54 to 263 residues, to reproduce a population of their low energy conformations. The 1,000 lowest energy solutions are identical in the stochastic (with two different seed numbers) and full, exhaustive searches for six of eight proteins. The others retain the lowest 141 and 213 (of 1,000) conformations, depending on the seed number, and the maximal difference between stochastic and exhaustive is only about 0.15 Kcal/mol. The energy gap between the lowest and highest of the 1,000 low-energy conformers in eight proteins is between 0.55 and 3.64 Kcal/mol. This algorithm offers real opportunities for solving problems of high complexity in structural biology and in other fields of science and technology. PMID:11792838

Comparison of self-report-based and physical performance-based frailty definitions among patients receiving maintenance hemodialysis.

PubMed

Johansen, Kirsten L; Dalrymple, Lorien S; Delgado, Cynthia; Kaysen, George A; Kornak, John; Grimes, Barbara; Chertow, Glenn M

2014-10-01

A well-accepted definition of frailty includes measurements of physical performance, which may limit its clinical utility. In a cross-sectional study, we compared prevalence and patient characteristics based on a frailty definition that uses self-reported function to the classic performance-based definition and developed a modified self-report-based definition. Prevalent adult patients receiving hemodialysis in 14 centers around San Francisco and Atlanta in 2009-2011. Self-report-based frailty definition in which a score lower than 75 on the Physical Function scale of the 36-Item Short Form Health Survey (SF-36) was substituted for gait speed and grip strength in the classic definition; modified self-report definition with optimized Physical Function score cutoff points derived in a development (one-half) cohort and validated in the other half. Performance-based frailty defined as 3 of the following: weight loss, weakness, exhaustion, low physical activity, and slow gait speed. 387 (53%) patients were frail based on self-reported function, of whom 209 (29% of the cohort) met the performance-based definition. Only 23 (3%) met the performance-based definition of frailty only. The self-report definition had 90% sensitivity, 64% specificity, 54% positive predictive value, 93% negative predictive value, and 72.5% overall accuracy. Intracellular water per kilogram of body weight and serum albumin, prealbumin, and creatinine levels were highest among nonfrail individuals, intermediate among those who were frail by self-report, and lowest among those who also were frail by performance. Age, percentage of body fat, and C-reactive protein level followed an opposite pattern. The modified self-report definition had better accuracy (84%; 95% CI, 79%-89%) and superior specificity (88%) and positive predictive value (67%). Our study did not address prediction of outcomes. Patients who meet the self-report-based but not the performance-based definition of frailty may represent an intermediate phenotype. A modified self-report definition can improve the accuracy of a questionnaire-based method of defining frailty. Published by Elsevier Inc.

2014 CRL Build Study of Life Insurance Applicants.

PubMed

Fulks, Michael; Dolan, Vera F; Stout, Robert L

2016-01-01

Objective .- Determine the impact of build on insurance applicant mortality accounting for smoking, laboratory test values and blood pressure. Method .- The study consisted of 2,051,370 applicants tested at Clinical Reference Laboratory between 1993 and 2007 with build and cotinine measurements available whose body mass index (BMI) was between 15 and 47. Vital status was determined as of September, 2011 by the Social Security Death Master File. Excluded from the primary study were applicants with HbA1c values ≥6.5%, systolic BP ≥141 mmHg, albumin values ≤3.3 g/dL or total cholesterol values ≤130 mg/dL. Relative mortality was determined by Cox regression analysis for bands of BMI split by age, sex and smoking status (urine cotinine positive). Results .- A majority of applicants had BMI >24 (overweight or obese by WHO criteria). After the exclusions noted above, relative mortality does not increase by >34% unless BMI is <20 (<18 for female non-smokers age 18 to 59) or BMI is >34. BMI values in the range of 22 to 24 and 25 to 29, overall, had similar and the lowest relative risks. For most nonsmokers, risk was lowest in the lower of these two BMI bands but for smokers (and non-smoking males age 60 to 89) risk was lowest in the higher BMI band. Additional analysis showed limited reduction in relative risk by accounting for all laboratory test values as well as continuing the exclusions. Eliminating the exclusions resulted in only a modest increase in relative risk because the mortality rate of the reference band increased as well. Conclusion .- After excluding elevated HbA1c and blood pressure (associated with high BMI) and low albumin and cholesterol (associated with low BMI) which are usually evaluated separately, mortality varies by a limited degree for BMI 20 to 34. Accounting for the mortality impact of other test values, in addition to the exclusions noted, reduced mortality associated with high BMI to a limited extent, but had little impact on mortality associated with low BMI.

Effect of Self-etch Adhesives on Self-sealing Ability of High-Copper Amalgams

PubMed Central

Moazzami, Saied Mostafa; Moosavi, Horieh; Moddaber, Maryam; Parvizi, Reza; Moayed, Mohamad Hadi; Mokhber, Nima; Meharry, Michael; B Kazemi, Reza

2016-01-01

Statement of the Problem: Similar to conventional amalgam, high-copper amalgam alloy may also undergo corrosion, but it takes longer time for the resulting products to reduce microleakage by sealing the micro-gap at the tooth/amalgam interface. Purpose: The aim of this study was to evaluate the effect of self-etch adhesives with different pH levels on the interfacial corrosion behavior of high-copper amalgam restoration and its induction potential for self-sealing ability of the micro-gap in the early hours after setting by means of Electro-Chemical Tests (ECTs). Materials and Method: Thirty cylindrical cavities of 4.5mm x 4.7mm were prepared on intact bicuspids. The samples were divided into five main groups of application of Adhesive Resin (AR)/ liner/ None (No), on the cavity floor. The first main group was left without an AR/ liner (No). In the other main groups, the types of AR/ liner used were I-Bond (IB), Clearfil S3 (S3), Single Bond (SB) and Varnish (V). Each main group (n=6) was divided into two subgroups (n=3) according to the types of the amalgams used, either admixed ANA 2000 (ANA) or spherical Tytin (Tyt). The ECTs, Open Circuit Potential (OCP), and the Linear Polarization Resistance (LPR) for each sample were performed and measured 48 hours after the completion of the samples. Results: The Tyt-No and Tyt-IB samples showed the highest and lowest OCP values respectively. In LPR tests, the Rp values of ANA-V and Tyt-V were the highest (lowest corrosion rate) and contrarily, the ANA-IB and Tyt-IB samples, with the lowest pH levels, represented the lowest Rp values (highest corrosion rates). Conclusion: Some self-etch adhesives may increase interfacial corrosion potential and self-sealing ability of high-copper amalgams. PMID:27942548

Calculated electric dipole moment of NiH X2Delta

NASA Technical Reports Server (NTRS)

Walch, S.; Bauschlicher, C. W., Jr.; Langhoff, S. R.

1985-01-01

A calculated dipole moment of 2.39 D at R sub e = 2.79 a sub 0 is reported, obtained from complete active space SCF/configuration interaction calculations plus one natural orbital iteration. The calculation is in good agreement with the experimental value of 2.4 + or - 0.1 D measured for the lowest vibrational level. In agreement with Gray et al. (1985), it is found that the dipole moment is strongly correlated with the 3d electron population; the good agreement with experiment thus provides verification of the mixed state model of NiH. It is concluded that the electric dipole moment of NiH is a sensitive test of the quality of the NiH wave function.

O+OH-->O(2)+H: A key reaction for interstellar chemistry. New theoretical results and comparison with experiment.

PubMed

Lique, F; Jorfi, M; Honvault, P; Halvick, P; Lin, S Y; Guo, H; Xie, D Q; Dagdigian, P J; Kłos, J; Alexander, M H

2009-12-14

We report extensive, fully quantum, time-independent (TID) calculations of cross sections at low collision energies and rate constants at low temperatures for the O+OH reaction, of key importance in the production of molecular oxygen in cold, dark, interstellar clouds and in the chemistry of the Earth's atmosphere. Our calculations are compared with TID calculations within the J-shifting approximation, with wave-packet calculations, and with quasiclassical trajectory calculations. The fully quantum TID calculations yield rate constants higher than those from the more approximate methods and are qualitatively consistent with a low-temperature extrapolation of earlier experimental values but not with the most recent experiments at the lowest temperatures.

The uptake of plutonium-238, 239, 240, americium-241, strontium-90 and caesium-137 into potatoes.

PubMed

Popplewell, D S; Ham, G J; Johnson, T E; Stather, J W; Sumner, S A

1984-09-01

Transfer factors have been measured for 239 Pu + 240 Pu, 241 Am, 90 Sr and 137 Cs into potatoes grown in a blend of soil which included silt polluted with radioactive waste discharged into the Irish Sea. The experiment has been carried out over four seasons and attempts to assess the radiological consequences to the consumer which would arise if potatoes were to be grown in land heavily contaminated with the silt. During the course of the experiment plutonium and americium became less available for uptake, 90 Sr became slightly more available and 137 Cs remained nearly constant in its availability. The values of the transfer factors are among the lowest reported for these radionuclides into potatoes.

The two-dimensional kinetic ballooning theory for ion temperature gradient mode in tokamak

NASA Astrophysics Data System (ADS)

Xie, T.; Zhang, Y. Z.; Mahajan, S. M.; Hu, S. L.; He, Hongda; Liu, Z. Y.

2017-10-01

The two-dimensional (2D) kinetic ballooning theory is developed for the ion temperature gradient mode in an up-down symmetric equilibrium (illustrated via concentric circular magnetic surfaces). The ballooning transform converts the basic 2D linear gyro-kinetic equation into two equations: (1) the lowest order equation (ballooning equation) is an integral equation essentially the same as that reported by Dong et al., [Phys. Fluids B 4, 1867 (1992)] but has an undetermined Floquet phase variable, (2) the higher order equation for the rapid phase envelope is an ordinary differential equation in the same form as the 2D ballooning theory in a fluid model [Xie et al., Phys. Plasmas 23, 042514 (2016)]. The system is numerically solved by an iterative approach to obtain the (phase independent) eigen-value. The new results are compared to the two earlier theories. We find a strongly modified up-down asymmetric mode structure, and non-trivial modifications to the eigen-value.

[Harmonization of TSH Measurements.

PubMed

Takeoka, Keiko; Hidaka, Yoh; Hishinuma, Akira; Ikeda, Katsuyoshi; Okubo, Shigeo; Tsuchiya, Tatsuyuki; Hashiguchi, Teruto; Furuta, Koh; Hotta, Taeko; Matsushita, Kazuyuki; Matsumoto, Hiroyuki; Murakami, Masami; Maekawa, Masato

2016-05-01

The measured concentration of thyroid stimulating hormone (TSH) differs depending on the reagents used. Harmonization of TSH is crucial because the decision limits are described in current clinical practice guide- lines as absolute values, e.g. 2.5 mIU/L in early pregnancy. In this study, we tried to harmonize the report- ed concentrations of TSH using the all-procedure trimmed mean. TSH was measured in 146 serum samples, with values ranging from 0.01 to 18.8 mIU/L, using 4 immunoassays. The concentration of TSH was highest with E test TOSOH and lowest with LUMIPULSE. The concentrations with each reagent were recalculated with the following formulas: E test TOSOH 0.855x-0.014; ECLusys 0.993x+0.079; ARCHITECT 1.041x- 0.010; and LUMIPULSE 1.096x-0.015. Recalculation eliminated the between-assay discrepancy. These formulas may be used until harmonization of TSH is achieved by the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC).

Substantial reservoirs of molecular hydrogen in the debris disks around young stars.

PubMed

Thi, W F; Blake, G A; van Dishoeck, E F; van Zadelhoff, G J; Horn, J M; Becklin, E E; Mannings, V; Sargent, A I; van Den Ancker, M E; Natta, A

2001-01-04

Circumstellar accretion disks transfer matter from molecular clouds to young stars and to the sites of planet formation. The disks observed around pre-main-sequence stars have properties consistent with those expected for the pre-solar nebula from which our own Solar System formed 4.5 Gyr ago. But the 'debris' disks that encircle more than 15% of nearby main-sequence stars appear to have very small amounts of gas, based on observations of the tracer molecule carbon monoxide: these observations have yielded gas/dust ratios much less than 0.1, whereas the interstellar value is about 100 (ref. 9). Here we report observations of the lowest rotational transitions of molecular hydrogen (H2) that reveal large quantities of gas in the debris disks around the stars beta Pictoris, 49 Ceti and HD135344. The gas masses calculated from the data are several hundreds to a thousand times greater than those estimated from the CO observations, and yield gas/dust ratios of the same order as the interstellar value.

Variations of L- and D-amino acid levels in the brain of wild-type and mutant mice lacking D-amino acid oxidase activity.

PubMed

Du, Siqi; Wang, Yadi; Weatherly, Choyce A; Holden, Kylie; Armstrong, Daniel W

2018-05-01

D-amino acids are now recognized to be widely present in organisms and play essential roles in biological processes. Some D-amino acids are metabolized by D-amino acid oxidase (DAO), while D-Asp and D-Glu are metabolized by D-aspartate oxidase (DDO). In this study, levels of 22 amino acids and the enantiomeric compositions of the 19 chiral proteogenic entities have been determined in the whole brain of wild-type ddY mice (ddY/DAO +/+ ), mutant mice lacking DAO activity (ddY/DAO -/- ), and the heterozygous mice (ddY/DAO +/- ) using high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). No significant differences were observed for L-amino acid levels among the three strains except for L-Trp which was markedly elevated in the DAO +/- and DAO -/- mice. The question arises as to whether this is an unknown effect of DAO inactivity. The three highest levels of L-amino acids were L-Glu, L-Asp, and L-Gln in all the three strains. The lowest L-amino acid level was L-Cys in ddY/DAO +/- and ddY/DAO -/- mice, while L-Trp showed the lowest level in ddY/DAO +/+ mice. The highest concentration of D-amino acid was found to be D-Ser, which also had the highest % D value (~ 25%). D-Glu had the lowest % D value (~ 0.01%) in all the three strains. Significant differences of D-Leu, D-Ala, D-Ser, D-Arg, and D-Ile were observed in ddY/DAO +/- and ddY/DAO -/- mice compared to ddY/DAO +/+ mice. This work provides the most complete baseline analysis of L- and D-amino acids in the brains of ddY/DAO +/+ , ddY/DAO +/- , and ddY/DAO -/- mice yet reported. It also provides the most effective and efficient analytical approach for measuring these analytes in biological samples. This study provides fundamental information on the role of DAO in the brain and may be relevant for future development involving novel drugs for DAO regulation.

Mapping intramuscular tenderness variation in four major muscles of the beef round.

PubMed

Reuter, B J; Wulf, D M; Maddock, R J

2002-10-01

The objective of this study was to quantify intramuscular tenderness variation within four muscles from the beef round: biceps femoris (BF), semitendinosus (ST), semimembranosus (SM), and adductor (AD). At 48 h postmortem, the BF, ST, SM, and AD were dissected from either the left or right side of ten carcasses, vacuum packaged, and aged for an additional 8 d. Each muscle was then frozen and cut into 2.54-cm-thick steaks perpendicular to the long axis of the muscle. Steaks were broiled on electric broilers to an internal temperature of 71 degrees C. Location-specific cores were obtained from each cooked steak, and Warner-Bratzler shear force was evaluated. Definable intramuscular shear force variation (SD = 0.56 kg) was almost twice as large as between-animal shear force variation (SD = 0.29 kg) and 2.8 times as large as between-muscle variation (SD = 0.20 kg). The ranking of muscles from greatest to least definable intramuscular shear force variation was BF, SM, ST, and AD (SD = 1.09, 0.72, 0.29, and 0.15 kg, respectively). The BF had its lowest shear force values at the origin (sirloin end), intermediate shear force values at the insertion, and its highest shear force values in a middle region 7 to 10 cm posterior to the sirloin-round break point (P < 0.05). The BF had lower shear force values toward the ST side than toward the vastus lateralis side (P < 0.05). The ST had its lowest shear force values in a 10-cm region in the middle, and its highest shear force values toward each end (P < 0.05). The SM had its lowest shear force values in the first 10-cm from the ischial end (origin), and its highest shear force values in a 13-cm region at the insertion end (P < 0.05). Generally, shear force was lower toward the superficial (medial) side than toward the deep side of the SM (P < 0.05). There were no intramuscular differences in shear force values within the AD (P > 0.05). These data indicate that definable intramuscular tenderness variation is substantial and could be used to develop alternative fabrication and(or) merchandising methods for beef round muscles.

Validation of mothers' reports of dietary intake by four to seven year-old children.

PubMed Central

Basch, C E; Shea, S; Arliss, R; Contento, I R; Rips, J; Gutin, B; Irigoyen, M; Zybert, P

1990-01-01

The validity of mothers' recall of four to seven year-old children's diet was assessed among 46 first generation Latino immigrant families from the Dominican Republic by comparing intake recalled by the mother to unobtrusive home observations of children. Correlations were moderate to high for calories and for most nutrients. There were no differences in mean intake of total calories or in intake of most macronutrients and micronutrients assessed. At least two-thirds of the children in the lowest (or highest) quintile based on home observations were correctly classified into the lowest or second lowest (or highest) quintiles based on mother's reports for calories and most nutrients. For all food items that were both observed and reported, 51 percent of reported portion sizes were equivalent to observed portion sizes, 15.5 percent were smaller, and 33.5 percent were larger. There was fair to good agreement on the number of food items eaten, with the exception of vegetables. Mothers' recall appears to be useful for classifying children by intake of calories, macronutrients and micronutrients, but provides a somewhat less accurate measure of actual foods eaten, portion sizes, and nutrient levels consumed. PMID:2240296

Sizes of particles formed during municipal wastewater treatment.

PubMed

Lech, Smoczynski; Marta, Kosobucka; Michal, Smoczynski; Harsha, Ratnaweera; Krystyna, Pieczulis-Smoczynska

2017-02-01

Volumetric diameters Dv and specific surface area SpS of sludge particles formed during chemical coagulation and electrocoagulation of sewage were determined. The obtained aggregate-flocs differed substantially in both Dv and SpS values. The differences in Dv and SpS values of the analyzed particles were interpreted based on theoretical models for expanding aggregates. The most uniform particles were formed under exposure to: (a) optimal and maximal doses of PIX, (b) optimal doses of PAX, (c) maximal doses of the Al electro-coagulant. The lowest PIX dose produced the least uniform particles. Sludge aggregates-particles produced under exposure to minimal doses of PIX and the Al electro-coagulant were characterized by the lowest SpS values. Sludge particles coagulated by PAX and the particles formed at higher doses of PIX and the Al electro-coagulant had higher SpS values. The particles formed at all doses of the applied coagulants and electro-coagulants were generally classified into two size ranges: the main range and the secondary range. Most particles belonged to the main size range. An increase in the percentage of colloidal hydroxide particles in sewage sludge increased SpS.

[A four year study of the personal and interpersonal value systems of freshman nursing students at Yonsei University].

PubMed

Choi, Y S

1991-01-01

The purpose of this study was to determine the values of freshman nursing students and to determine changes each year over the four years of the study and to provide base data for curriculum and student guidance. The sample consisted of the freshman students who entered college of nursing from 1988 through 1991. The total sample was 358 students and data were collected during March of each of the four years. The data were analyzed using t-test, ANOVA and Pearson Correlation to examine the relationship between the subcategories of values and Duncan multiple range test to examine the relationship between the scores for each year and the demographic data. The instrument used in this study was the Survey of Personal Values and Interpersonal Values modified by UngYun Hwang and KyungHae Lee in accordance with L.V. Gordon's instrument. This tool provides scores on practical mindedness, achievement, variety, decisiveness, orderliness, goal orientation, support, conformity, recognition, independence, benevolence and leadership. The results of the study were as follows: 1. The nursing freshman students surveyed had the highest score for goal orientation (21.44) and the lowest for variety (17.13) on the SPV (Survey of Personal Values) and the highest score for benevolence (21.19) and lowest for leadership (17.00) on the SIV (Survey of Interpersonal Values). In accordance with the standardized scores for Gordon's SPV for other woman college students, the students in the study were between the 78%ile-97%ile and were in the 72%ile-97%ile for the SIV. 2. When t-test scores were compared, no significant variation was found between the years for each of the values (P less than .05). 3. A significant variation was found on variety, between 1989 and 1991 (P less than .05), and between 1988 and 1991. The highest score was in 1991 in both comparisons. Supporting was also higher for 1991 than for 1988 (P less than .05). 4. Religion and occupation of father did not show any significant differences (P less than .05). There was no significant difference in values according to the student's religion or the occupation of their father. Students born in the metropolitan area had a higher score on variety than those from the rural area and vice versa on regularity (P less than .05). The results of this study show that there is a higher score on values for Y University freshman than shown for freshmen in other universities reported from other research. To keep or promote values, it is very important that there be a systematic strategy of education and special educational programs.

First Results of Nitrate and its Stable Isotopic Composition in an Ice Core from Dome A, East Antarctica

NASA Astrophysics Data System (ADS)

Jiang, S.

2017-12-01

During the 21st Chinese Antarctic Research Expedition in 2004/2005 austral summer, a 109.91 m ice core (hereafter DA2005 core) was recovered at the site about 300 m away from the summit of Dome A. The top 100.42 m was analyzed for major chemical impurities and isotopic composition of nitrate. Dating was based on the volcanic stratigraphy and average annual accumulation rate. Results showed that the analyzed 100.42 m part of the core covers the last 2840 years before present, from 840 BC to AD 1998. Nitrate concentration in the DA2005 core varies between 2.86 μg kg-1 and 30.75 μg kg-1 throughout the 2840 years, with the mean concentration of 11.84 µg kg-1. Comparisons with previous Antarctic ice core nitrate records show that the DA2005 core has the lowest mean concentration of nitrate, which is consistent with the lowest accumulation rate at Dome A among these sampling sites. Decreased nitrate concentration during the period of Little Ice Age (AD 1500-1900) is observed in the DA2005 core. The δ15N(NO3-) values vary between 235.4 ‰ and 279.4 ‰, which suggest strong 15N enrichment in the DA2005 core. The sample covering the most recent time period (AD 1695-1838) has the lowest δ15N(NO3-) value. The Δ17O(NO3-) values span from 28.9 ‰ to 31.4 ‰, which is among the range ever observed. An increasing trend is seen during the period of AD 1225-1838, which corresponds to the time period when nitrate concentration remains low. The maximum Δ17O(NO3-) value occurs in the period AD 1695-1838, and the minimum value occurs in the period AD 62-166.

Marine Fog over the Western Pacific Marginal Seas Based Upon Ship Observations for 1950 - 2007

NASA Astrophysics Data System (ADS)

Dorman, C. E.; Koracin, D. R.

2016-12-01

An analysis is presented of the marine fog distribution over the western Pacific marginal seas based upon the International Comprehensive Ocean-Atmosphere Data Set (ICOADS) ship observations taken during 1950-2007. Fog occurrence is reported in routine weather reports that are encoded in an ICOADS ship observation. This includes the marginal seas of Okhotsk Sea, Japan Sea, Yellow Sea and South China Sea which have significant fog occurrences with values much greater than in the surrounding ocean with distinct seasonal trends but different generation mechanisms. The greatest occurrence is 55 % in Jun-Jul-Aug over the Okhotsk Sea followed by 28 % over the Japan Sea. This is seasonally controlled by the sea level pressure gradient moving air over a negative sea surface temperature gradient. During Dec-Jan-Feb, the SLP gradient reverses, moving cold, dry continental air over the Okhotsk and Japan Seas, eliminating any fog. The maximum fog over the Okhotsk Sea is over isolated locations with shallow water. In the Japan Sea, the most frequent fog occurs along the north side of the sea over a narrow shelf with the lowest SST of the entire Sea. In the Yellow Sea, the fog frequency peak is from Dec through May. In Mar-Apr-May the highest value is 18 % which is centered at 33 N 122 W while elevated values extend along the China coast to Taiwan. In Jun-Jul-Aug, highest values are mostly confined to the Yellow Sea. In Dec-Jan-Feb, decreased but significant fog occurrences extend along the entire China coast when the highest value in the Yellow Sea is 5 % and in South China Sea it is 6 %. The only other world marine fog occurrence analysis discovered by us is a US Department of Agriculture Jun-Jul-Aug marine fog frequency chart published in 1938 that does not show any fog in the Okhotsk Sea and misses most of the fog occurrence reported by ships in the Yellow Sea.

Mechanical properties and microstructures of glass-ionomer cements.

PubMed

Xie, D; Brantley, W A; Culbertson, B M; Wang, G

2000-03-01

The objective of this study was to determine the flexural strength (FS), compressive strength (CS), diametral tensile strength (DTS), Knoop hardness (KHN) and wear resistance of ten commercial glass-ionomer cements (GICs). The fracture surfaces of these cements were examined using scanning electron microscopic (SEM) techniques to ascertain relationships between the mechanical properties and microstructures of these cements. Specimens were fabricated according to the instructions from each manufacturer. The FS, CS, DTS, KHN and wear rate were measured after conditioning the specimens for 7 d in distilled water at 37 degrees C. One-way analysis of variance with the post hoc Tukey-Kramer multiple range test was used to determine which specimen groups were significantly different for each test. The fracture surface of one representative specimen of each GIC from the FS tests was examined using a scanning electron microscope. The resin-modified GICs (RM GICs) exhibited much higher FS and DTS, not generally higher CS, often lower Knoop hardness and generally lower wear resistance, compared to the conventional GICs (C GICs). Vitremer (3M) had the highest values of FS and DTS; Fuji II LC (GC International) and Ketac-Molar (ESPE) had the highest CS; Ketac-Fil (ESPE) had the highest KHN. Ketac-Bond (ESPE) had the lowest FS; alpha-Silver (DMG-Hamburg) had the lowest CS. Four GICs (alpha-Fil (DMG-Hamburg), alpha-Silver, Ketac-Bond and Fuji II) had the lowest values of DTS, which were not significantly different from each other; alpha-Silver and Ketac-Silver had the lowest values of KHN. The highest wear resistance was exhibited by alpha-Silver and Ketac-Fil; F2LC had the lowest wear resistance. The C GICs exhibited brittle behavior, whereas the RM GICs underwent substantial plastic deformation in compression. The more integrated the microstructure, the higher were the FS and DTS. Higher CS was correlated with smaller glass particles, and higher KHN was found where there was a combination of smaller glass particles and lower porosity. Larger glass particle sizes and a more integrated microstructure contributed to a higher wear resistance. The mechanical properties of GICs were closely related to their microstructures. Factors such as the integrity of the interface between the glass particles and the polymer matrix, the particle size, and the number and size of voids have important roles in determining the mechanical properties.

Adjusting to future demands in healthcare: Curriculum changes and nursing students' self-reported professional competence.

PubMed

Theander, Kersti; Wilde-Larsson, Bodil; Carlsson, Marianne; Florin, Jan; Gardulf, Ann; Johansson, Eva; Lindholm, Christina; Nordström, Gun; Nilsson, Jan

2016-02-01

Nursing competence is of significant importance for patient care. Newly graduated nursing students rate their competence as high. However, the impact of different designs of nursing curricula on nursing students' self-reported nursing competence areas is seldom reported. To compare newly graduated nursing students' self-reported professional competence before and after the implementation of a new nursing curriculum. The study had a descriptive comparative design. Nursing students, who graduated in 2011, having studied according to an older curriculum, were compared with those who graduated in 2014, after a new nursing curriculum with more focus on person-centered nursing had been implemented. A higher education nursing program at a Swedish university. In total, 119 (2011 n=69, 2014 n=50) nursing students responded. Nursing students' self-reported professional competencies were assessed with the Nurse Professional Competence (NPC) scale. There were no significant differences between the two groups of nursing students, who graduated in 2011 and 2014, respectively, with regard to age, sex, education, or work experience. Both groups rated their competencies as very high. Competence in value-based nursing was perceived to be significantly higher after the change in curriculum. The lowest competence, both in 2011 and 2014, was reported in education and supervision of staff and students. Our findings indicate that newly graduated nursing students - both those following the old curriculum and the first batch of students following the new one - perceive that their professional competence is high. Competence in value-based nursing, measured with the NPC scale, was reported higher after the implementation of a new curriculum, reflecting curriculum changes with more focus on person-centered nursing. Copyright © 2015 Elsevier Ltd. All rights reserved.

Toxicological benchmarks for screening potential contaminants of concern for effects on aquatic biota: 1994 Revision

DOE Office of Scientific and Technical Information (OSTI.GOV)

Suter, G.W. II; Mabrey, J.B.

1994-07-01

This report presents potential screening benchmarks for protection of aquatic life from contaminants in water. Because there is no guidance for screening benchmarks, a set of alternative benchmarks is presented herein. The alternative benchmarks are based on different conceptual approaches to estimating concentrations causing significant effects. For the upper screening benchmark, there are the acute National Ambient Water Quality Criteria (NAWQC) and the Secondary Acute Values (SAV). The SAV concentrations are values estimated with 80% confidence not to exceed the unknown acute NAWQC for those chemicals with no NAWQC. The alternative chronic benchmarks are the chronic NAWQC, the Secondary Chronicmore » Value (SCV), the lowest chronic values for fish and daphnids from chronic toxicity tests, the estimated EC20 for a sensitive species, and the concentration estimated to cause a 20% reduction in the recruit abundance of largemouth bass. It is recommended that ambient chemical concentrations be compared to all of these benchmarks. If NAWQC are exceeded, the chemicals must be contaminants of concern because the NAWQC are applicable or relevant and appropriate requirements (ARARs). If NAWQC are not exceeded, but other benchmarks are, contaminants should be selected on the basis of the number of benchmarks exceeded and the conservatism of the particular benchmark values, as discussed in the text. To the extent that toxicity data are available, this report presents the alternative benchmarks for chemicals that have been detected on the Oak Ridge Reservation. It also presents the data used to calculate benchmarks and the sources of the data. It compares the benchmarks and discusses their relative conservatism and utility.« less

Air temperature and humidity diversity in the Hornsund fjord area (Spitsbergen) in the period 1 July 2014 - 30 June 2015

NASA Astrophysics Data System (ADS)

Przybylak, Rajmund; Araźny, Andrzej; Wyszyński, Przemysław; Budzik, Tomasz; Wawrzyniak, Tomasz

2016-04-01

The article presents preliminary results of studies into the spatial diversity of air temperature and relative humidity (overground layer, 2 m a.g.l.) in the area of the Hornsund fjord (S Spitsbergen, approx. 77°N), based on data collected between 1 July 2014 and 30 June 2015. The Hornsund fjord runs latitudinal along approx. 40 km and its average width is about 10 km. Numerous glaciers flow into the fjord and the mountain ridges around it often exceed 700 m a.s.l. Data series obtained from 11 sites equipped with automatic weather stations (Vaisala, Campbell, Davis) or HOBO temperature and humidity sensors were used. Two sites (Hornsund HOR and the Hans Glacier HG4) have been operating for years, whereas 9 new ones (Bogstranda BOG, Fugleberget FUG, Gnålodden GNA, Gåshamnoyra GAS, Hyttevika HYT, Lisbetdalen LIS, Ostrogradskijfjella OST, Treskelodden TRE and Wilczekodden WIL) were established within the Polish-Norwegian AWAKE-2 project. Three of the sites (BOG, GAS and OST) were damaged by polar bears, hence their measurement series are shorter. A substantial spatial diversity was found in the air temperature and relative humidity in the area, mostly influenced by elevation, type of surface and distance from the Greenland Sea's open water. During the year (July 2014 - June 2015), the areas of HYT (-1.1°C) and WIL (-1.9°C) were the warmest. Both sites are located on the west coast of the fjord. The HYT demonstrates the most favourable temperature conditions, being orographically sheltered from the east and its cold and dry air masses. The coldest sites were the mountain-top site of FUG (-5.9°C) and the glacier-located HG4 (-4.3°C). The low temperature at FUG resulted from its elevation (568 m a.s.l.), whereas at HG4 (184 m a.s.l) the glaciated surface also added up to the result. In the analysed period, the annual course of air temperature in the area had a clear minimum in February, when the lowest mean monthly values ranged from -9.4°C at HYT to -15.1°C at FUG. The highest temperature was recorded at all the sites in July, when its highest mean values were observed at GAS and HYT (6.1°C and 6.0°C, respectively), while the lowest occurred at FUG (2.4°C) and HG4 (3.1°C). The other meteorological element considered was relative humidity, which positively correlates with the course of air temperature. During the year, the most humid sites were those located at the mountain top (FUG) and on the Treskelen peninsula (TRE), towards the end of the fjord (94% and 91%, respectively). The lowest RH values were measured at HOR and HYT (80% in both). In the annual course, the lowest RH was observed in February with the lowest mean monthly values (74%) at HOR and HYT, and the highest at FUG (88%) and TRE (87%). As with air temperature, the highest relative humidity occurred in July. Its lowest mean values were recorded at HOR (87%), and the highest - at FUG (96%).

Fatty acid composition and quality characteristics of low-fat cooked sausages made with beef and chicken meat, tomato juice and sunflower oil.

PubMed

Yılmaz, Í; Simşek, O; Işıklı, M

2002-10-01

Low-fat (5.9-10.3% fat) cooked sausages were produced with seven different formulations. Sausages produced with total replacement of fat with sunflower oil had significantly lower oleic acid (C18:1) and higher linoleic (C18:2) and behenic (C22:0) fatty acid contents. Their ratio of TUFA/TS was 3.65 compared to 0.95-1.14 for the other sausages. Also these sausages had the lowest moisture content, highest overall palatability and were less firm. Sausages with tomato juice had the lowest pH value, total aerobic count and nitrite content, but were firmer. Sausages produced with reduced beef contents had lower fat contents, lower stearic (C18:0) and higher oleic (C18:1) fatty acid contents than sausages of high beef content, their texture was very soft and had the lowest score for juiciness. Finally the sausages with chicken meat had the lowest fat and highest salt contents, and lower stearic (C18:0) and higher linoleic (C18:3) fatty acid contents than those made with beef . Also their colour was lighter, less red and more yellow and they had the lowest flavor intensity and overall acceptability.

The role of charge in the surfactant-assisted stabilization of the natural product curcumin.

PubMed

Wang, Zifan; Leung, Mandy H M; Kee, Tak W; English, Douglas S

2010-04-20

Colloidal solutions of surfactants that form micelles or vesicles are useful for solubilizing and stabilizing hydrophobic molecules that are otherwise sparingly soluble in aqueous solutions. In this paper we investigate the use of micelles and vesicles prepared from ionic surfactants for solubilizing and stabilizing curcumin, a medicinal natural product that undergoes alkaline hydrolysis in water. We identify spectroscopic signatures to evaluate curcumin partitioning and deprotonation in surfactant mixtures containing micelles or vesicles. These spectroscopic signatures allow us to monitor the interaction of curcumin with charged surfactants over a wide range of pH values. Titration data are presented to show the pH dependence of curcumin interactions with negatively and positively charged micelles and vesicles. In solutions of cationic micelles or positively charged vesicles, strong interaction between the Cur(-1) phenoxide ion and the positively charged surfactants results in a change in the acidity of the phenolic hydrogen and a lowering of the apparent lowest pK(a) value for curcumin. In the microenvironments formed by anionic micelles or negatively charged bilayers, our data indicates that curcumin partitions as the Cur(0) species, which is stabilized by interactions with the respective surfactant aggregates, and this leads to an increase in the apparent pK(a) values. Our results may explain some of the discrepancies within the literature with respect to reported pK(a) values and the acidity of the enolic versus phenolic protons. Hydrolysis rates, quantum yields, and molar absorption coefficients are reported for curcumin in a variety of solutions.

Alcohol and ischaemic heart disease in middle aged British men.

PubMed Central

Shaper, A G; Phillips, A N; Pocock, S J; Walker, M

1987-01-01

The relation between alcohol intake and ischaemic heart disease was examined in a large scale prospective study of middle aged men drawn from general practices in 24 British towns. After an average follow up of 6.2 years 335 of the 7729 men had experienced a myocardial infarction (fatal or non-fatal) or sudden cardiac death. No significant relation was found between reported alcohol intake and the incidence of such events. Though the group of light daily drinkers had the lowest incidence of ischaemic heart disease events, it also contained the lowest proportion of current smokers, had the lowest mean blood pressure, had the lowest mean body mass index, and contained the lowest proportion of manual workers. These characteristics are more likely to account for the apparent protective effect of alcohol against ischaemic heart disease than a direct effect of alcohol. Compared with the effects of established risk factors alcohol seems to be quite unimportant in the development of ischaemic heart disease. PMID:3105714

Trawl-based assessment of Lake Ontario pelagic prey fishes including Alewife and Rainbow Smelt

USGS Publications Warehouse

Weidel, Brian C.; Walsh, Maureen; Connerton, Michael J.; Holden, Jeremy P.

2017-01-01

Managing Lake Ontario fisheries in an ecosystem-context, requires reliable data on the status and trends of prey fishes that support predator populations. We report on the community and population dynamics of Lake Ontario pelagic prey fishes, based on bottom trawl surveys. We emphasize information that supports the international Lake Ontario Committee’s Fish Community Objectives. In 2016, 142 bottom trawls were collected in U.S. waters, and for the first time 46 trawls were conducted in Canadian waters. A total of 420,386 fish from 24 species were captured. Alewife were 89% of the total fish catch and 93% of the pelagic prey fish catch. The Rainbow Smelt abundance index in U.S. waters increased slightly in 2016 relative to 2015. Interestingly, the Rainbow Smelt abundance index from tows in Canadian waters was 35% higher than the U.S. index. Abundances of Threespine Stickleback and Emerald Shiners in both U.S. and Canadian waters were low in 2016 relative to their peak abundances in the late 1990s, but Cisco abundance indices suggest a recent increase in their abundance. This year, the reported Alewife abundance time series was truncated to only include values since 1997, which were collected with the same trawl and eliminated the need to adjust values for different trawls. The 2016 adult Alewife abundance index was the second lowest abundance ever observed in the time series. This value was expected to decline from the 2015 value since the indices of juvenile Alewife were low in 2014 and the lowest ever observed in 2015. The fall condition index of adult Alewife increased in 2016 and is consistent with lower abundance and reduced competition for zooplankton resources. The 2016 Age-1 Alewife index increased relative to 2014 and 2015, and suggested lake conditions were favorable for Age-1 survival and growth during the summer of 2015 and the 2015-2016 winter. Interestingly, the catch of adult and Age1 Alewife was higher in trawls conducted in Canadian waters relative to U. S. waters. The larger trawl catches in Canadian waters suggest there may be important spatial differences in lake-wide distribution of prey fishes in April when trawling is conducted. Future surveys should to continue to sample at the whole-lake scale to understand the year to year variability in spatial distribution and the physical or biotic factors driving those distribution differences.

Stable isotopes document the trophic structure of a deep-sea cephalopod assemblage including giant octopod and giant squid.

PubMed

Cherel, Y; Ridoux, V; Spitz, J; Richard, P

2009-06-23

Although deep-sea cephalopods are key marine organims, their feeding ecology remains essentially unknown. Here, we report for the first time the trophic structure of an assemblage of these animals (19 species) by measuring the isotopic signature of wings of their lower beaks, which accumulated in stomachs of stranded sperm whales. Overall, the species encompassed a narrow range in delta(13)C values (1.7 per thousand), indicating that they lived in closely related and overlapping habitats. delta(13)C values can be interpreted in terms of distribution with the more (13)C-depleted species (e.g. Stigmatoteuthis arcturi, Vampyroteuthis infernalis) having a more pelagic habitat than the more (13)C-enriched, bathyal species (e.g. Todarodes sagittatus and the giant squid Architeuthis dux). The cephalopods sampled had delta(15)N values ranging 4.6 per thousand, which is consistent with the species spanning approximately 1.5 trophic levels. Neither the giant octopod (Haliphron atlanticus) nor the giant squid reached the highest trophic position. Species delta(15)N was independent of body size, with large squids having both the highest (Taningia danae) and lowest (Lepidoteuthis grimaldii) delta(15)N values. Their trophic position indicates that some species share the top of the food web, together with other megacarnivores such as the sperm whale.

Zonisamide serum concentrations during pregnancy.

PubMed

Reimers, Arne; Helde, Grethe; Becser Andersen, Noémi; Aurlien, Dag; Surlien Navjord, Elisabeth; Haggag, Kathrine; Christensen, Jakob; Lillestølen, Kari Mette; Nakken, Karl Otto; Brodtkorb, Eylert

2018-05-04

To investigate the change in zonisamide (ZNS) serum concentration and its consequences in pregnant women with epilepsy. Six hospitals in Norway and Denmark screened their records for women who had been using ZNS during pregnancy. Absolute serum concentrations as well as concentration/dose (CD)-ratios were compared to non-pregnant values. Descriptive data on seizure control and obstetrical data were also collected. 144 serum concentrations from 23 pregnancies in 15 individual women with epilepsy were included (six on monotherapy). The mean ZNS serum concentration fell to a minimum of 58.6 ± 15.1%, while the C/D-ratio fell to as low as 55.1 ± 15.3% of the non-pregnant-value. The lowest values were seen in gestational months six to nine, and the individual nadir varied considerably (range: 24-81% of the non-pregnant value). Four out of ten previously seizure-free patients experienced breakthrough seizures. Gestational age, weight at birth and head circumference of the newborns were within the reference ranges. ZNS serum concentrations may fall by over 40% during pregnancy, with large interindividual variability. In some patients, this may lead to worsened seizure control. These findings are in line with reports on other AEDs and suggest that regular therapeutic drug monitoring and dose adjustments may be useful. Copyright © 2018 Elsevier B.V. All rights reserved.

Convergence of decision rules for value-based pricing of new innovative drugs.

PubMed

Gandjour, Afschin

2015-04-01

Given the high costs of innovative new drugs, most European countries have introduced policies for price control, in particular value-based pricing (VBP) and international reference pricing. The purpose of this study is to describe how profit-maximizing manufacturers would optimally adjust their launch sequence to these policies and how VBP countries may best respond. To decide about the launching sequence, a manufacturer must consider a tradeoff between price and sales volume in any given country as well as the effect of price in a VBP country on the price in international reference pricing countries. Based on the manufacturer's rationale, it is best for VBP countries in Europe to implicitly collude in the long term and set cost-effectiveness thresholds at the level of the lowest acceptable VBP country. This way, international reference pricing countries would also converge towards the lowest acceptable threshold in Europe.

The effects of selected pre-treatments on germination of seeds of Oriental hornbeam (Carpinus orientalis).

PubMed

Ozel, Halil Bariş

2016-07-01

In the present study, the effect of some pre-treatments implemented on seeds of Oriental hornbeam (Carpinus orientalis), which has wide geographical variation along Turkey on germination percentage values were investigated. For this purpose, 13 different pre-treatments were implemented to seeds obtained from 17 different populations. According to the obtained results (except control seeds), pre-treatments leading to lowest germination percentage value (8.1%) in Oriental hornbeam seeds was PT10: Keeping seeds for 90 min in sulfuric acid, while highest germination percentage (86.58%) has been obtained with pre-treatment PT13: Implementation of 40% dose of Baikal EM1 + Biohoumous mixture to the seeds, while lowest germination percentage (40.50%) was observed on seeds collected from P7 (Bartin-Kozcağiz) population, highest germination percentage was observed in seeds obtained from P17 (Artvin-Hopa) population.

Fatty acid profiles of five farmed Brazilian freshwater fish species from different families

PubMed Central

Canto, Anna Carolina Vilhena da Cruz Silva; da Costa, Marion Pereira; da Silva, Flávio Alves; Mársico, Eliane Teixeira; Conte-Junior, Carlos Adam

2017-01-01

The proximate composition and fatty acid (FA) profiles of five Brazilian freshwater fish species, namely Brycon cephalus (BC), Cichla ocellaris (CO), Prochilodus lineatus (PL), Leporinus friderici (LF) and Pseudoplatystoma corruscans (PCO), were investigated. CO and LF exhibited the highest (p < 0.05) moisture content, as well as one of the lowest (p < 0.05) lipid values, whereas BC presented the lowest (p < 0.05) moisture and, alongside PL, the highest (p < 0.05) lipid content. The predominant FAs in the evaluated fish species were palmitic, oleic, linoleic and docosahexaenoic acids. BC and CO presented high n-3 PUFA content, especially DHA, and demonstrated superior nutritional quality indices compared to the other evaluated fish species. Furthermore, a significant relationship was observed among these species, suggesting they possess similar nutritional lipid values. Thus, BC and CO were proven to be an excellent matrix with relevant lipid quality, desirable for human health. PMID:28614390

Characterising the variations in ethnic skin colours: a new calibrated data base for human skin.

PubMed

Xiao, K; Yates, J M; Zardawi, F; Sueeprasan, S; Liao, N; Gill, L; Li, C; Wuerger, S

2017-02-01

Accurate skin colour measurements are important for numerous medical applications including the diagnosis and treatment of cutaneous disorders and the provision of maxillofacial soft tissue prostheses. In this study, we obtained accurate skin colour measurements from four different ethnic groups (Caucasian, Chinese, Kurdish, Thai) and at four different body locations (Forehead, cheek, inner arm, back of hand) with a view of establishing a new skin colour database for medical and cosmetic applications. Skin colours are measured using a spectrophotometer and converted to a device-independent standard colour appearance space (CIELAB) where skin colour is expressed as values along the three dimensions: Lightness L*, Redness a* and Yellowness b*. Skin colour differences and variation are then evaluated as a function of ethnicity and body location. We report three main results: (1) When plotted in a standard colour appearance space (CIELAB), skin colour distributions for the four ethnic groups overlap significantly, although there are systematic mean differences. Between ethnicities, the most significant skin colour differences occur along the yellowness dimension, with Thai skin exhibiting the highest yellowness (b*) value and Caucasian skin the lowest value. Facial redness (a*) is invariant across the four ethnic groups. (2) Between different body locations, there are significant variations in redness (a*), with the forehead showing the highest redness value and the inner arm the lowest. (3) The colour gamut is smallest in the Chinese sample and largest in the Caucasian sample, with the Chinese gamut lying entirely the Caucasian gamut. Similarly, the largest variability in skin tones is found in the Caucasian group, and the smallest in the Chinese group. Broadly speaking, skin colour variation can be explained by two main factors: individual differences in lightness and yellowness are mostly due to ethnicity, whereas differences in redness are primarily due to different body locations. Variations in lightness are more idiosyncratic probably reflecting the large influence of environmental factors such as exposure to sun. © 2016 The Authors. Skin Research and Technology Published by John Wiley & Sons Ltd.

Cultural differences in family, marital, and gender-role values among immigrants and majority members in the Netherlands.

PubMed

Arends-Tóth, Judit; van de Vijver, Fons J R

2009-06-01

This study examined the size of differences in self-reported family, marital, and gender-role values in five cultural groups in the Netherlands (6338 Dutch mainstreamers and 422 Turkish, 369 Moroccan, 429 Surinamese, and 394 Antillean first- and second-generation immigrants). It was found that the three value scales were neither completely independent, nor could they be merged into a single value scale. The factor structures of all scales were identical for the five cultural groups, implying that the concepts can be compared. Age, sex, and notably education accounted for a substantial part of the cultural differences in all values. Cultural differences were larger for marital and family values than for gender-role values. Family and marital values yielded the same rank order of mean scores in the five cultural groups: Turks and Moroccans scored the lowest (having the most traditional values), followed by Surinamers, Antilleans, and Dutch mainstreamers. This rank order corresponds with the ethnic hierarchy of cultural groups that is based on the evaluation of ethnic groups by mainstreamers according to their liking of and likeness to ethnic groups. Generational differences were not found for family and gender-role values but first-generation immigrants in all groups had more traditional marital values than had second-generation immigrants. It was concluded that the theoretical framework based on a combination of three Hofstede dimensions (individualism-collectivism, power-distance, and femininity-masculinity), a model of the hierarchy of the ethnic groups in the Dutch society, and acculturation theory provided an adequate way to address family, marital, and gender-role value differences in the five cultural groups.

Apolipoprotein E polymorphism in Southern Iran: E4 allele in the lowest reported amounts.

PubMed

Bazrgar, Masood; Karimi, Mehran; Fathzadeh, Mohsen; Senemar, Sara; Peiravian, Farah; Shojaee, Ashraf; Saadat, Mostafa

2008-12-01

Apolipoprotein E (apoE) with three major alleles E2, E3 and E4 is one of the critical genes in lipid metabolism. Common apoE alleles are in association with an increase in risk for central nervous and cardiovascular diseases such as Alzheimer's disease, dementia, multiple sclerosis, atherosclerosis, coronary heart disease, hyperlipoproteinemia and stroke. ApoE3 is known as the most frequent allele in all populations, while association of apoE gene polymorphism with reported diseases have mostly been related to other two major alleles especially apoE4. To determine of apoE alleles frequencies in Southern Iran and comparison of those frequencies with other populations. DNA was extracted from the whole blood of 198 healthy unrelated candidates from population of Fars Province, Southern Iran, for apoE genotyping who were checked up by a physician. The frequencies of apoE alleles were compared with other populations by chi(2) test. The frequencies of E2, E3 and E4 were 0.063, 0.886 and 0.051 respectively. These values were similar to those reported from populations of Kuwait, Oman, Lebanon, India, Turkey, Greece, Spain, Sardinia Islands of Italy and two Iranian populations but were different from South of Italy and Caucasians in other Europe regions, American, American-Indian, African, East Asian and Saudi populations (P < 0.05). The frequency of E4 allele as a genetic risk factor for some multifactorial diseases in the population of Southern Iran is in the lowest reported amounts in the world. Iranian population has Caucasoid origin but differs from some Caucasian populations in Europe and America. The results of present study are in agreement with the historical evidences which show admixture of Iranian population with other populations and some studies based on genetic polymorphisms in the population of Southern Iran.

INSIGHT AND SELF-STIGMA IN PATIENTS WITH SCHIZOPHRENIA.

PubMed

Vidović, Domagoj; Brecić, Petrana; Vilibić, Maja; Jukić, Vlado

2016-03-01

Poor insight and high level of self-stigma are often present among patients with schizophrenia and are related to poorer treatment adherence, poorer social function and rehabilitation, aggressive behavior, higher level of depression, social anxiety, lower quality of life and self-esteem. Reports on a relationship between insight and stigma are controversial. We examined the relationship of the level of insight and self-stigma in a sample of 149 patients with schizophrenia. Insight was measured with the Scale to assess Unawareness of Mental Disorder and self-stigma with the Internalized Stigma of Mental Illness. Results showed 88.6% of the patients to have high or moderate insight, with a mean value of 2.73. General insight showed the highest level (2.58) and insight in positive symptoms the lowest level (2.9). The self-stigma score in general was 2.13, with stereotype endorsement being lowest (1.98). According to study results, 77.1% of patients felt minimal or low self-stigma across all subscales, except for stigma resistance subscale. Statistically significant correlation was found between insight and four subscales of self-stigma, while no correlation was found for the stigma resistance subscale only. These results imply the need of individually tailored antistigma and insight promoting programs for patients with schizophrenia.

Coffee Intake and Incidence of Erectile Dysfunction.

PubMed

Lopez, David S; Liu, Lydia; Rimm, Eric B; Tsilidis, Konstantinos K; de Oliveira Otto, Marcia; Wang, Run; Canfield, Steven; Giovannucci, Edward

2018-05-01

Coffee intake is suggested to have a positive impact on chronic diseases, yet its role in urological diseases such as erectile dysfunction (ED) remains unclear. We investigated the association of coffee intake with incidence of ED by conducting the Health Professionals Follow-Up Study, a prospective analysis of 21,403 men aged 40-75 years old. Total, regular, and decaffeinated coffee intakes were self-reported on food frequency questionnaires. ED was assessed by mean values of questionnaires in 2000, 2004 and 2008. Multivariable adjusted Cox proportional hazards models were used to compute hazard ratios for patients with incident ED (n = 7,298). No significant differences were identified for patients with incident ED after comparing highest (≥4 cups/day) with lowest (0 cups/day) categories of total (hazard ratio (HR) = 1.00, 95% confidence interval (CI): 0.90, 1.11) and regular coffee intakes (HR = 1.00, 95% CI: 0.89, 1.13). When comparing the highest category with lowest category of decaffeinated coffee intake, we found a 37% increased risk of ED (HR = 1.37, 95% CI: 1.08, 1.73), with a significant trend (P trend = 0.02). Stratified analyses also showed an association among current smokers (P trend = 0.005). Overall, long-term coffee intake was not associated with risk of ED in a prospective cohort study.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lin, Xiaomei; Lv, Xin; Wang, Limin

Graphical abstract: - Highlights: • Effect of CTAB on the morphology and crystallization of MnFe{sub 2}O{sub 4}. • The lowest coercivity of MnFe{sub 2}O{sub 4} polyhedron is 11.9 Oe. • MnFe{sub 2}O{sub 4} as anode for LIB shows good reversible capacity and cycle performances. - Abstract: The uniform different morphologies MnFe{sub 2}O{sub 4}, including cube, truncated cube, polyhedron and octahedron, were successfully synthesized via a solvothermal route using cetyltrimethylammonium bromide. The results of control experiments revealed that the concentration of cetyltrimethylammonium bromide was an important factor, which affected the morphology and crystallization of MnFe{sub 2}O{sub 4} submicro-crystals. All the preparedmore » samples exhibited soft-magnetic behavior at room temperature. Especially, the coercivity of MnFe{sub 2}O{sub 4} polyhedron with 200 nm diameter was 11.9 Oe, which was among the lowest values reported so far. Moreover, MnFe{sub 2}O{sub 4} submicro-crystals with special morphologies demonstrated higher reversible capacity (about 1000 mAh g{sup −1}) and different cycle performances. After 50 cycles, polyhedron structure remained 428 mAh/g. The MnFe{sub 2}O{sub 4} would have a potential application as anode material for lithium ion batteries.« less

Milk production and nutrient partitioning as measured by (13)C enrichment of milk components during C3 and C4 plant feeding in purebred Holstein and in Charolais × Holstein F2 crossbred cows.

PubMed

Hillal, Hany; Voigt, Jürgen; Metges, Cornelia C; Hammon, Harald M

2015-01-01

Nutrient partitioning was investigated in cows with different genetic merits for milk production by measuring (13)C/(12)C ratios (reported by delta values δ(13)C) in milk components in response to C3 (grass silage) and C4 diets (corn silage). We hypothesised that changes of δ(13)C in milk differ between Holstein (HOL; high milk production) and Charolais × Holstein cows with medium (CHM) and low (CHL) milk production. Changes of δ(13)C (Δδ(13)C) in milk components were estimated by calculating differences of δ(13)C due to switch from C3 to C4 feeding. After switch to C4 feeding, Δδ(13)C of lactose was greater in HOL than in CHL. Immediate Δδ(13)C of milk fat was the lowest in CHL. The maximal Δδ(13)C of casein was the lowest in HOL. The proportion of carbon in milk derived from diet increased with milk yield, indicating the main impact of the milk production level, but minor impact of breed, on nutrient partitioning towards the mammary gland.

40 CFR Appendix N to Part 50 - Interpretation of the National Ambient Air Quality Standards for PM2.5

Code of Federal Regulations, 2010 CFR

2010-07-01

... values in the composite site record are used in annual mean and 98th percentile calculations, however... highest to the lowest number. Using the left column of table 1, determine the appropriate range (i.e., row... column identifies the rank of the annual 98th percentile value in the descending sorted list of daily...

40 CFR Appendix N to Part 50 - Interpretation of the National Ambient Air Quality Standards for PM2.5

Code of Federal Regulations, 2011 CFR

2011-07-01

... values in the composite site record are used in annual mean and 98th percentile calculations, however... highest to the lowest number. Using the left column of table 1, determine the appropriate range (i.e., row... column identifies the rank of the annual 98th percentile value in the descending sorted list of daily...

Intracellular accumulation dynamics and fate of zinc ions in alveolar epithelial cells exposed to airborne ZnO nanoparticles at the air–liquid interface

DOE PAGES

Mihai, Cosmin; Chrisler, William B.; Xie, Yumei; ...

2013-12-02

Airborne nanoparticles (NPs) that enter the respiratory tract are likely to reach the alveolar region. Accumulating observations support a role for zinc oxide (ZnO) NP dissolution in toxicity, but the majority of in vitro studies were conducted in cells exposed to NPs in growth media, where large doses of dissolved ions are shed into the exposure solution. To determine the precise intracellular accumulation dynamics and fate of zinc ions (Zn 2+) shed by airborne NPs in the cellular environment, we exposed alveolar epithelial cells to aerosolized NPs at the air-liquid interface (ALI). Using a fluorescent indicator for Zn 2+, togethermore » with organelle-specific fluorescent proteins, we quantified Zn 2+ in single cells and organelles over time. We found that at the ALI, intracellular Zn 2+ values peaked 3 h post exposure and decayed to normal values by 12 h, while in submersed cultures, intracellular Zn 2+ values continued to increase over time. The lowest toxic NP dose at the ALI generated peak intracellular Zn 2+ values that were nearly 3 folds lower than the peak values generated by the lowest toxic dose of NPs in submersed cultures, and 8 folds lower than the peak values generated by the lowest toxic dose of ZnSO4 or Zn 2+. At the ALI, the majority of intracellular Zn 2+ was found in endosomes and lysosomes as early as 1 h post exposure. In contrast, the majority of intracellular Zn 2+ following exposures to ZnSO 4 was found in other larger vesicles, with less than 10% in endosomes and lysosomes. In conclusion, together, our observations indicate that low but critical levels of intracellular Zn 2+ have to be reached, concentrated specifically in endosomes and lysosomes, for toxicity to occur, and point to the focal dissolution of the NPs in the cellular environment and the accumulation of the ions specifically in endosomes and lysosomes as the processes underlying the potent toxicity of airborne ZnO NPs.« less

Analysis of storage possibility of raw and smoked breast meat of oat-fattened White Kołuda® goose based on their quality characteristics.

PubMed

Damaziak, K; Stelmasiak, A; Michalczuk, M; Wyrwisz, J; Moczkowska, M; Marcinkowska-Lesiak, M M; Niemiec, J; Wierzbicka, A

2016-09-01

Raw and smoked (spickgans) fillets of oat-fattened White Kołuda® goose were packed in: PET - ethylene terephthalate bags; VSP - 99% vacuum; MAP1 - 80% O2, 20% CO2; MAP2 - 70% N2, 30% O2; MAP3 - 30% O2, 40% N2, 30% CO2, and stored at a temperature of 2°C. On the day of packaging (0 d) and during storage of raw (5, 7, 10 d) and smoked fillets (5, 10, 15 d), the samples were analyzed for weight losses, physicochemical traits, and chemical composition. The study demonstrated the effect of storage time and packaging method on storage yield of raw and smoked fillets. In VSP, the raw fillets were characterized by the lowest amount of leakage, whereas spickgans were characterized by the highest storage yield and weight loss. The analysis of the effect of the modified atmosphere demonstrated the lowest weight loss of raw fillets at, simultaneously, the smallest amount of leakage in MAP1. The spickgans stored in MAP2 showed higher weight, higher yield after storage, and lower storage loss in all terms of analyses compared to MAP1 and MAP3. The greatest cooking loss at simultaneously the lowest pH values was determined for the samples stored in VSP. The WBSF values of raw fillets were decreasing along with storage time, in contrast to WBSF values of spickgans, in which case the value of this parameter increased compared to 0 d. Raw fillets stored in MAP1 and MAP3 were characterized by the most significant increase in the value of L*, by a decrease in the value of a* and an increase in that of b* parameter. Visual assessment of spickgans on 15 d of storage revealed the presence of white sediment on the surface of products, except for the samples stored in VSP. The study demonstrated the effect of storage time on the contents of protein and fat in raw fillets and on the contents of salt and fat in spickgans. © 2016 Poultry Science Association Inc.

Intracellular accumulation dynamics and fate of zinc ions in alveolar epithelial cells exposed to airborne ZnO nanoparticles at the air–liquid interface

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mihai, Cosmin; Chrisler, William B.; Xie, Yumei

Airborne nanoparticles (NPs) that enter the respiratory tract are likely to reach the alveolar region. Accumulating observations support a role for zinc oxide (ZnO) NP dissolution in toxicity, but the majority of in vitro studies were conducted in cells exposed to NPs in growth media, where large doses of dissolved ions are shed into the exposure solution. To determine the precise intracellular accumulation dynamics and fate of zinc ions (Zn 2+) shed by airborne NPs in the cellular environment, we exposed alveolar epithelial cells to aerosolized NPs at the air-liquid interface (ALI). Using a fluorescent indicator for Zn 2+, togethermore » with organelle-specific fluorescent proteins, we quantified Zn 2+ in single cells and organelles over time. We found that at the ALI, intracellular Zn 2+ values peaked 3 h post exposure and decayed to normal values by 12 h, while in submersed cultures, intracellular Zn 2+ values continued to increase over time. The lowest toxic NP dose at the ALI generated peak intracellular Zn 2+ values that were nearly 3 folds lower than the peak values generated by the lowest toxic dose of NPs in submersed cultures, and 8 folds lower than the peak values generated by the lowest toxic dose of ZnSO4 or Zn 2+. At the ALI, the majority of intracellular Zn 2+ was found in endosomes and lysosomes as early as 1 h post exposure. In contrast, the majority of intracellular Zn 2+ following exposures to ZnSO 4 was found in other larger vesicles, with less than 10% in endosomes and lysosomes. In conclusion, together, our observations indicate that low but critical levels of intracellular Zn 2+ have to be reached, concentrated specifically in endosomes and lysosomes, for toxicity to occur, and point to the focal dissolution of the NPs in the cellular environment and the accumulation of the ions specifically in endosomes and lysosomes as the processes underlying the potent toxicity of airborne ZnO NPs.« less

Intracellular accumulation dynamics and fate of zinc ions in alveolar epithelial cells exposed to airborne ZnO nanoparticles at the air–liquid interface

PubMed Central

Mihai, Cosmin; Chrisler, William B.; Xie, Yumei; Hu, Dehong; Szymanski, Craig J.; Tolic, Ana; Klein, Jessica A.; Smith, Jordan N.; Tarasevich, Barbara J.; Orr, Galya

2015-01-01

Airborne nanoparticles (NPs) that enter the respiratory tract are likely to reach the alveolar region. Accumulating observations support a role for zinc oxide (ZnO) NP dissolution in toxicity, but the majority of in-vitro studies were conducted in cells exposed to NPs in growth media, where large doses of dissolved ions are shed into the exposure solution. To determine the precise intracellular accumulation dynamics and fate of zinc ions (Zn2+) shed by airborne NPs in the cellular environment, we exposed alveolar epithelial cells to aerosolized NPs at the air–liquid interface (ALI). Using a fluorescent indicator for Zn2+, together with organelle-specific fluorescent proteins, we quantified Zn2+ in single cells and organelles over time. We found that at the ALI, intracellular Zn2+ values peaked 3 h post exposure and decayed to normal values by 12 h, while in submerged cultures, intracellular Zn2+ values continued to increase over time. The lowest toxic NP dose at the ALI generated peak intracellular Zn2+ values that were nearly three-folds lower than the peak values generated by the lowest toxic dose of NPs in submerged cultures, and eight-folds lower than the peak values generated by the lowest toxic dose of ZnSO4 or Zn2+. At the ALI, the majority of intracellular Zn2+ was found in endosomes and lysosomes as early as 1 h post exposure. In contrast, the majority of intracellular Zn2+ following exposures to ZnSO4 was found in other larger vesicles, with less than 10% in endosomes and lysosomes. Together, our observations indicate that low but critical levels of intracellular Zn2+ have to be reached, concentrated specifically in endosomes and lysosomes, for toxicity to occur, and point to the focal dissolution of the NPs in the cellular environment and the accumulation of the ions specifically in endosomes and lysosomes as the processes underlying the potent toxicity of airborne ZnO NPs. PMID:24289294

Intracellular accumulation dynamics and fate of zinc ions in alveolar epithelial cells exposed to airborne ZnO nanoparticles at the air-liquid interface.

PubMed

Mihai, Cosmin; Chrisler, William B; Xie, Yumei; Hu, Dehong; Szymanski, Craig J; Tolic, Ana; Klein, Jessica A; Smith, Jordan N; Tarasevich, Barbara J; Orr, Galya

2015-02-01

Airborne nanoparticles (NPs) that enter the respiratory tract are likely to reach the alveolar region. Accumulating observations support a role for zinc oxide (ZnO) NP dissolution in toxicity, but the majority of in-vitro studies were conducted in cells exposed to NPs in growth media, where large doses of dissolved ions are shed into the exposure solution. To determine the precise intracellular accumulation dynamics and fate of zinc ions (Zn(2+)) shed by airborne NPs in the cellular environment, we exposed alveolar epithelial cells to aerosolized NPs at the air-liquid interface (ALI). Using a fluorescent indicator for Zn(2+), together with organelle-specific fluorescent proteins, we quantified Zn(2+) in single cells and organelles over time. We found that at the ALI, intracellular Zn(2+) values peaked 3 h post exposure and decayed to normal values by 12 h, while in submerged cultures, intracellular Zn(2+) values continued to increase over time. The lowest toxic NP dose at the ALI generated peak intracellular Zn(2+) values that were nearly three-folds lower than the peak values generated by the lowest toxic dose of NPs in submerged cultures, and eight-folds lower than the peak values generated by the lowest toxic dose of ZnSO4 or Zn(2+). At the ALI, the majority of intracellular Zn(2+) was found in endosomes and lysosomes as early as 1 h post exposure. In contrast, the majority of intracellular Zn(2+) following exposures to ZnSO4 was found in other larger vesicles, with less than 10% in endosomes and lysosomes. Together, our observations indicate that low but critical levels of intracellular Zn(2+) have to be reached, concentrated specifically in endosomes and lysosomes, for toxicity to occur, and point to the focal dissolution of the NPs in the cellular environment and the accumulation of the ions specifically in endosomes and lysosomes as the processes underlying the potent toxicity of airborne ZnO NPs.

Handling the procurement of prostheses for total hip replacement: description of an original value based approach and application to a real-life dataset reported in the UK

PubMed Central

Messori, Andrea; Trippoli, Sabrina; Marinai, Claudio

2017-01-01

Objectives In most European countries, innovative medical devices are not managed according to cost–utility methods, the reason being that national agencies do not generally evaluate these products. The objective of our study was to investigate the cost-utility profile of prostheses for hip replacement and to calculate a value-based score to be used in the process of procurement and tendering for these devices. Methods The first phase of our study was aimed at retrieving the studies reporting the values of QALYs, direct cost, and net monetary benefit (NMB) from patients undergoing total hip arthroplasty (THA) with different brands of hip prosthesis. The second phase was aimed at calculating, on the basis of the results of cost–utility analysis, a tender score for each device (defined according to standard tendering equations and adapted to a 0–100 scale). This allowed us to determine the ranking of each device in the simulated tender. Results We identified a single study as the source of information for our analysis. Nine device brands (cemented, cementless, or hybrid) were evaluated. The cemented prosthesis Exeter V40/Elite Plus Ogee, the cementless device Taperloc/Exceed, and the hybrid device Exeter V40/Trident had the highest NMB (£152 877, £156 356, and £156 210, respectively) and the best value-based tender score. Conclusions The incorporation of value-based criteria in the procurement process can contribute to optimising the value for money for THA devices. According to the approach described herein, the acquisition of these devices does not necessarily converge on the product with the lowest cost; in fact, more costly devices should be preferred when their increased cost is offset by the monetary value of the increased clinical benefit. PMID:29259062

Information presentation features and comprehensibility of hospital report cards: design analysis and online survey among users.

PubMed

Sander, Uwe; Emmert, Martin; Dickel, Jochen; Meszmer, Nina; Kolb, Benjamin

2015-03-16

Improving the transparency of information about the quality of health care providers is one way to improve health care quality. It is assumed that Internet information steers patients toward better-performing health care providers and will motivate providers to improve quality. However, the effect of public reporting on hospital quality is still small. One of the reasons is that users find it difficult to understand the formats in which information is presented. We analyzed the presentation of risk-adjusted mortality rate (RAMR) for coronary angiography in the 10 most commonly used German public report cards to analyze the impact of information presentation features on their comprehensibility. We wanted to determine which information presentation features were utilized, were preferred by users, led to better comprehension, and had similar effects to those reported in evidence-based recommendations described in the literature. The study consisted of 5 steps: (1) identification of best-practice evidence about the presentation of information on hospital report cards; (2) selection of a single risk-adjusted quality indicator; (3) selection of a sample of designs adopted by German public report cards; (4) identification of the information presentation elements used in public reporting initiatives in Germany; and (5) an online panel completed an online questionnaire that was conducted to determine if respondents were able to identify the hospital with the lowest RAMR and if respondents' hospital choices were associated with particular information design elements. Evidence-based recommendations were made relating to the following information presentation features relevant to report cards: evaluative table with symbols, tables without symbols, bar charts, bar charts without symbols, bar charts with symbols, symbols, evaluative word labels, highlighting, order of providers, high values to indicate good performance, explicit statements of whether high or low values indicate good performance, and incomplete data ("N/A" as a value). When investigating the RAMR in a sample of 10 hospitals' report cards, 7 of these information presentation features were identified. Of these, 5 information presentation features improved comprehensibility in a manner reported previously in literature. To our knowledge, this is the first study to systematically analyze the most commonly used public reporting card designs used in Germany. Best-practice evidence identified in international literature was in agreement with 5 findings about German report card designs: (1) avoid tables without symbols, (2) include bar charts with symbols, (3) state explicitly whether high or low values indicate good performance or provide a "good quality" range, (4) avoid incomplete data (N/A given as a value), and (5) rank hospitals by performance. However, these findings are preliminary and should be subject of further evaluation. The implementation of 4 of these recommendations should not present insurmountable obstacles. However, ranking hospitals by performance may present substantial difficulties.

Electron impact excitation of Kr XXVIII

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aggarwal, K.M., E-mail: K.Aggarwal@qub.ac.u; Keenan, F.P.; Lawson, K.D.

2011-05-15

Collision strengths ({Omega}) are calculated for all 6328 transitions among the lowest 113 levels belonging to the 2s{sup 2}2p{sup 5},2s2p{sup 6},2s{sup 2}2p{sup 4}3l,2s2p{sup 5}3l, and 2p{sup 6}3l configurations of fluorine-like krypton, Kr XXVIII, using the Dirac Atomic R-matrix Code. All partial waves with angular momentum J{<=}40 are included, sufficient for the convergence of {Omega} for forbidden transitions. For allowed transitions a top-up is employed to obtain converged values of {Omega} up to an energy of 400 Ryd. Resonances in the thresholds region are resolved on a narrow energy mesh, and results for effective collision strengths (Y) are obtained after averagingmore » the values of {Omega} over a Maxwellian distribution of electron velocities. Values of Y are reported over a wide temperature range below 10{sup 7.1}K, and the accuracy of the results is assessed. In addition, effective collision strengths are listed for the temperature range 7.0{<=}logT{sub e}(K){<=}9.0, obtained from non-resonant collision strengths generated with the FAC code.« less

Copper detection in the Asiatic clam Corbicula fluminea: optimum valve closure response.

PubMed

Tran, Damien; Fournier, Elodie; Durrieu, Gilles; Massabuau, Jean-Charles

2004-02-25

When exposed to a contaminant, bivalves close their shell as a protective strategy. The aim of the present study was to estimate the maximum expected dissolved copper sensitivity in the freshwater bivalve Corbicula fluminea using a new approach to determine their potential and limit to detect contaminants. To take into account the rate of spontaneous closures, we integrated stress problems associated with fixation by a valve in usual valvometers and the spontaneous rhythm associated with nycthemeral activity, to optimize the response in conditions where the probability of spontaneous closing was lowest. Moreover, we used an original system with impedance valvometry, using lightweight impedance electrodes, to study free-ranging animals in low stress conditions combined with an analytical approach describing dose-response curves by logistic regression, with valve closure reaction as a function of response time and concentration of contaminant. In C. fluminea, we estimated that copper concentrations > 4 microg/l (95% confidence interval (CI95%), 2.3-8.8 microg/l) must be detected within 5 h after Cu addition. Lower values could not be distinguished from background noise. The threshold values were 2.5 times lower than the values reported in the literature.

Copper detection in the Asiatic clam Corbicula fluminea: optimum valve closure response.

PubMed

Tran, Damien; Fournier, Elodie; Durrieu, Gilles; Massabuau, Jean Charles

2003-11-19

When exposed to a contaminant, bivalves close their shell as a protective strategy. The aim of the present study was to estimate the maximum expected dissolved copper sensitivity in the freshwater bivalve Corbicula fluminea using a new approach to determine their potential and limit to detect contaminants. To take into account the rate of spontaneous closures, we integrated stress problems associated with fixation by a valve in usual valvometers and the spontaneous rhythm associated with nycthemeral activity, to optimize the response in conditions where the probability of spontaneous closing was lowest. Moreover, we used an original system with impedance valvometry, using lightweight impedance electrodes, to study free-ranging animals in low stress conditions combined with an analytical approach describing dose-response curves by logistic regression, with valve closure reaction as a function of response time and concentration of contaminant. In C. fluminea, we estimated that copper concentrations >4 microg/l (95% confidence interval (CI(95%)), 2.3-8.8 microg/l) must be detected within 5 h after Cu addition. Lower values could not be distinguished from background noise. The threshold values were 2.5 times higher than the values reported in the literature.

[Effects of tourism disturbance on plant diversity in Qingshan Lake scenic area of Zhejiang Province].

PubMed

Lu, Qing-Bin; You, Wei-Yun; Zhao, Chang-Jie; Wang, Xiang-Wei; Meng-Xiang, Xiu

2011-02-01

From May 2007 to June 2008, an investigation was made on the changes of plant community in Qingshan Lake scenic area of Zhejiang Province under the effects of tourism disturbance. With the increase of tourism disturbance, the importance value of the plants was mainly fastened on a few species such as Pinus hwangshanensis, apt to decrease for tree and shrub species and to increase for herb species, and the individuals of the plants increased. The values of richness index (D) and diversity index (H) were in the order of medium disturbance > slight disturbance > severe disturbance, while the evenness index (J) value was in the order of medium disturbance > severe disturbance > slight disturbance. At the same vegetation layers, only a few species such as Cinnamomum camphora existed under different disturbances, and thereby, the similarity index values were smaller than 0.500. Slight disturbance affected coniferous forest most, with the average values of D, H, and J being the lowest (1.188, 1.056, and 0.697, respectively); severe disturbance affected broadleaf forest and shrub-herbage most, with the D value (2.013) of shrub-herbage and the H value (1.286) and J value (0.807) of broadleaf forest being the lowest; while medium disturbance was favorable to the increase of plant diversity and to the normal exertion of ecosystem function. The eco-safety of the structural elements of plant community in the scenic area was threatened to some extent, resulting in the reduction of indigenous species such as Sinocalycanthus chinensis and the incursion of exotic species as Setaria viridis.

Postoperative Decrease in Platelet Counts Is Associated with Delayed Liver Function Recovery and Complications after Partial Hepatectomy.

PubMed

Takahashi, Kazuhiro; Kurokawa, Tomohiro; Oshiro, Yukio; Fukunaga, Kiyoshi; Sakashita, Shingo; Ohkohchi, Nobuhiro

2016-05-01

Peripheral platelet counts decrease after partial hepatectomy; however, the implications of this phenomenon are unclear. We assessed if the observed decrease in platelet counts was associated with postoperative liver function and morbidity (complications grade ≤ II according to the Clavien-Dindo classification). We enrolled 216 consecutive patients who underwent partial hepatectomy for primary liver cancers, metastatic liver cancers, benign tumors, and donor hepatectomy. We classified patients as either low or high platelet percentage (postoperative platelet count/preoperative platelet count) using the optimal cutoff value calculated by a receiver operating characteristic (ROC) curve analysis, and analyzed risk factors for delayed liver functional recovery and morbidity after hepatectomy. Delayed liver function recovery and morbidity were significantly correlated with the lowest value of platelet percentage based on ROC analysis. Using a cutoff value of 60% acquired by ROC analysis, univariate and multivariate analysis determined that postoperative lowest platelet percentage ≤ 60% was identified as an independent risk factor of delayed liver function recovery (odds ratio (OR) 6.85; P < 0.01) and morbidity (OR, 4.90; P < 0.01). Furthermore, patients with the lowest platelet percentage ≤ 60% had decreased postoperative prothrombin time ratio and serum albumin level and increased serum bilirubin level when compared with patients with platelet percentage ≥ 61%. A greater than 40% decrease in platelet count after partial hepatectomy was an independent risk factor for delayed liver function recovery and postoperative morbidity. In conclusion, the decrease in platelet counts is an early marker to predict the liver function recovery and complications after hepatectomy.

Nonlinear absorption properties of AlGaAs/GaAs multiple quantum wells grown by metalorganic chemical vapor deposition

NASA Technical Reports Server (NTRS)

Lee, Hsing-Chung; Kost, A.; Kawase, M.; Hariz, A.; Dapkus, P. Daniel

1988-01-01

The nonlinear absorption properties of the excitonic resonances associated with multiple quantum wells (MQWs) in AlGaAs/GaAs grown by metalorganic chemical vapor deposition are reported. The dependence of the saturation properties on growth parameters, especially growth temperature, and the well width are described. The minimum measured saturation intensity for these materials is 250 W/sq cm, the lowest reported value to date. The low saturation intensities are the result of excellent minority carrier properties. A systematic study of minority carrier lifetimes in quantum wells are reported. Lifetimes range from 50-350 ns depending on growth temperature and well width. When corrected for lateral diffusion effects and the measured minority carrier lifetime, the saturation data suggest that saturation intensities as low as 2.3 W/sq cm can be achieved in this system. The first measurements of the dependence of the exciton area and the magnitude of the excitonic absorption on well width are prsented. The growth of MQW structures on transparent GaP substrates is demonstrated and the electroabsorption properties of these structures are reviewed.

Dynamic Changes in Phenolics and Antioxidant Capacity during Pecan (Carya illinoinensis) Kernel Ripening and Its Phenolics Profiles.

PubMed

Jia, Xiaodong; Luo, Huiting; Xu, Mengyang; Zhai, Min; Guo, Zhongren; Qiao, Yushan; Wang, Liangju

2018-02-16

Pecan ( Carya illinoinensis ) kernels have a high phenolics content and a high antioxidant capacity compared to other nuts-traits that have attracted great interest of late. Changes in the total phenolic content (TPC), condensed tannins (CT), total flavonoid content (TFC), five individual phenolics, and antioxidant capacity of five pecan cultivars were investigated during the process of kernel ripening. Ultra-performance liquid chromatography coupled with quadruple time-of-flight mass (UPLC-Q/TOF-MS) was also used to analyze the phenolics profiles in mixed pecan kernels. TPC, CT, TFC, individual phenolics, and antioxidant capacity were changed in similar patterns, with values highest at the water or milk stages, lowest at milk or dough stages, and slightly varied at kernel stages. Forty phenolics were tentatively identified in pecan kernels, of which two were first reported in the genus Carya , six were first reported in Carya illinoinensis , and one was first reported in its kernel. The findings on these new phenolic compounds provide proof of the high antioxidant capacity of pecan kernels.

Relationship between literacy skills and self-reported health in the Nordic countries.

PubMed

Lundetræ, Kjersti; Gabrielsen, Egil

2016-12-01

This study investigated the association between literacy skills and self-reported health among Danish ( n = 7284), Finnish ( n = 5454), Norwegian ( n = 4942) and Swedish ( n = 4555) participants aged 16-65 years. Logistic regression models were used to assess the association between literacy skills and self-reported health after adjusting for sex, age and educational level. Nordic participants aged 16-65 years with literacy skills at the lowest level reported sub-optimal health more often (28-37%) than those with literacy skills at the highest level (7-9%). After adjusting for sex, age and educational level, the likelihood of reporting sub-optimal health was 1.99-3.24 times as high for those with literacy skills at the lowest level as for those with literacy skills at the highest level. These results suggest that poor literacy skills increase the likelihood of experiencing poor health in the Nordic countries, even after controlling for educational level.

40 CFR 1065.205 - Performance specifications for measurement instruments.

Code of Federal Regulations, 2014 CFR

2014-07-01

... are all determined with the same collected data, as described in § 1065.305, and based on absolute... meters to allow noise to be measured at the lowest calibrated value instead of zero flow rate. [79 FR...

Fault detection and diagnosis of diesel engine valve trains

NASA Astrophysics Data System (ADS)

Flett, Justin; Bone, Gary M.

2016-05-01

This paper presents the development of a fault detection and diagnosis (FDD) system for use with a diesel internal combustion engine (ICE) valve train. A novel feature is generated for each of the valve closing and combustion impacts. Deformed valve spring faults and abnormal valve clearance faults were seeded on a diesel engine instrumented with one accelerometer. Five classification methods were implemented experimentally and compared. The FDD system using the Naïve-Bayes classification method produced the best overall performance, with a lowest detection accuracy (DA) of 99.95% and a lowest classification accuracy (CA) of 99.95% for the spring faults occurring on individual valves. The lowest DA and CA values for multiple faults occurring simultaneously were 99.95% and 92.45%, respectively. The DA and CA results demonstrate the accuracy of our FDD system for diesel ICE valve train fault scenarios not previously addressed in the literature.

Revision Roux-en-Y Gastric Bypass to Biliopancreatic Long-Limb Gastric Bypass for Inadequate Weight Response: Case Series and Analysis.

PubMed

Buchwald, Henry; Oien, Danette M

2017-09-01

The long-limb Roux-en-Y gastric bypass (LLRYGB) was introduced in 1987 as a salvage operation for inadequate weight loss after a standard Roux-en-Y gastric bypass (RYGB). We report on 53 consecutive patients (44 females) with conversion of a failed RYGB to a LLRYGB performed by a single surgeon between 2002 and 2014. No patient had an ascertainable anatomic abnormality to explain his/her weight regain. LLRYGB revision consisted of a 75-cm to 100-cm alimentary Roux limb and a 75-cm to 100-cm common channel; after 2011, in suitable patients, the Roux limb was lengthened to greater than 250 cm. Average values for weight (lbs) were as follows: pre-original RYGB = 329; lowest measured after RYGB = 196; at time of LLRYGB = 285; and at 1, 2, 3, 4, >5 years post LLRYGB = 225, 207, 199, 197, 195, for a sustained weight loss >90 lbs. Average values for BMI (kg/m 2 ) were as follows: pre-original RYGB = 54.3; lowest measured after RYGB = 32.3; at time of LLRYGB = 47.2; and at 1, 2, 3, 4, >5 years post LLRYGB = 37.1, 34.4, 33.0, 32.8, 31.4, for a sustained BMI reduction >16.5 kg/m 2 . Zero operative mortality; 3 (5.7%) late deaths; 7 (13.2%) 30-day complications; 33 (62.3%) long-term complications with 23 (43.4%) needing TPN; and 14 (26.4%) requiring operative revision. A salvage LLRYGB procedure can be performed safely and is weight successful, but fraught with long-term nutritional problems and a high necessity for revision. A Roux segment over 250 cm may improve outcomes.

Recovery Efficiency, False Negative Rate, and Limit of Detection Performance of a Validated Macrofoam-Swab Sampling Method with Low Surface Concentrations of Two Bacillus anthracis Surrogates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Piepel, Gregory F.; Hutchison, Janine R.; Kaiser, Brooke L. D.

The performance of a macrofoam-swab sampling method was evaluated using Bacillus anthracis Sterne (BAS) and Bacillus atrophaeus Nakamura (BG) spores applied at nine low target amounts (2-500 spores) to positive-control plates and test coupons (2 in × 2 in) of four surface materials (glass, stainless steel, vinyl tile, and plastic). Test results from cultured samples were used to evaluate the effects of surrogate, surface concentration, and surface material on recovery efficiency (RE), false negative rate (FNR), and limit of detection. For RE, surrogate and surface material had statistically significant effects, but concentration did not. Mean REs were the lowest formore » vinyl tile (50.8% with BAS, 40.2% with BG) and the highest for glass (92.8% with BAS, 71.4% with BG). FNR values ranged from 0 to 0.833 for BAS and 0 to 0.806 for BG, with values increasing as concentration decreased in the range tested (0.078 to 19.375 CFU/cm2, where CFU denotes ‘colony forming units’). Surface material also had a statistically significant effect. A FNR-concentration curve was fit for each combination of surrogate and surface material. For both surrogates, the FNR curves tended to be the lowest for glass and highest for vinyl title. The FNR curves for BG tended to be higher than for BAS at lower concentrations, especially for glass. Results using a modified Rapid Viability-Polymerase Chain Reaction (mRV-PCR) analysis method were also obtained. The mRV-PCR results and comparisons to the culture results are discussed in a separate report.« less

Recovery Efficiency, False Negative Rate, and Limit of Detection Performance of a Validated Macrofoam-Swab Sampling Method with Low Surface Concentrations of Two Bacillus anthracis Surrogates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Piepel, Gregory F.; Hutchison, Janine R.; Deatherage Kaiser, Brooke L

The performance of a macrofoam-swab sampling method was evaluated using Bacillus anthracis Sterne (BAS) and Bacillus atrophaeus Nakamura (BG) spores applied at nine low target amounts (2-500 spores) to positive-control plates and test coupons (2 in. × 2 in.) of four surface materials (glass, stainless steel, vinyl tile, and plastic). Test results from cultured samples were used to evaluate the effects of surrogate, surface concentration, and surface material on recovery efficiency (RE), false negative rate (FNR), and limit of detection. For RE, surrogate and surface material had statistically significant effects, but concentration did not. Mean REs were the lowest formore » vinyl tile (50.8% with BAS, 40.2% with BG) and the highest for glass (92.8% with BAS, 71.4% with BG). FNR values ranged from 0 to 0.833 for BAS and 0 to 0.806 for BG, with values increasing as concentration decreased in the range tested (0.078 to 19.375 CFU/cm 2, where CFU denotes ‘colony forming units’). Surface material also had a statistically significant effect. A FNR-concentration curve was fit for each combination of surrogate and surface material. For both surrogates, the FNR curves tended to be the lowest for glass and highest for vinyl title. The FNR curves for BG tended to be higher than for BAS at lower concentrations, especially for glass. Results using a modified Rapid Viability-Polymerase Chain Reaction (mRV-PCR) analysis method were also obtained. The mRV-PCR results and comparisons to the culture results will be discussed in a subsequent report.« less

Psychosocial correlates of physical activity and sedentary leisure habits in young adolescents: the Teens Eating for Energy and Nutrition at School study.

PubMed

Schmitz, Kathryn H; Lytle, Leslie A; Phillips, Glenn A; Murray, David M; Birnbaum, Amanda S; Kubik, Martha Y

2002-02-01

Low levels of physical activity (PA) and highly sedentary leisure habits (SLH) in youth may establish behavioral patterns that will predispose youth to increased chronic disease risk in adulthood. The purpose of this paper was to examine associations of demographic and psychosocial factors with self-reported PA and SLH in young adolescents. A general linear mixed model predicted self-reported PA and SLH in the spring from demographic and psychosocial variables measured the previous fall in 3798 seventh grade students. PA and SLH differed by race, with Caucasian students reporting among the highest PA and lowest SLH. Perceptions of higher academic rank or expectations predicted higher PA and lower SLH. Depressive symptomatology predicted higher SLH scores but not PA. Higher self-reported value of health, appearance, and achievement predicted higher PA and lower SLH in girls. Girls who reported that their mothers had an authoritative parenting style also reported higher PA and lower SLH. Determinants of PA and SLH appear to differ from each other, particularly in boys. Development of effective programs to increase PA and/or decrease SLH in young adolescents should be based on a clear understanding of the determinants of these behaviors. Copyright 2002 American Health Foundation and Elsevier Science (USA).

The hydrodynamic theory of detonation

NASA Technical Reports Server (NTRS)

Langweiler, Heinz

1939-01-01

This report derives equations containing only directly measurable constants for the quantities involved in the hydrodynamic theory of detonation. The stable detonation speed, D, is revealed as having the lowest possible value in the case of positive material velocity, by finding the minimum of the Du curve (u denotes the speed of the gases of combustion). A study of the conditions of energy and impulse in freely suspended detonating systems leads to the disclosure of a rarefaction front traveling at a lower speed behind the detonation front; its velocity is computed. The latent energy of the explosive passes into the steadily growing detonation zone - the region between the detonation front and the rarefaction front. The conclusions lead to a new definition of the concept of shattering power. The calculations are based on the behavior of trinitrotoluene.

Abrupt GaN/p-GaN:Mg junctions grown via metalorganic chemical vapor deposition

NASA Astrophysics Data System (ADS)

Agarwal, Anchal; Gupta, Chirag; Alhassan, Abdullah; Mates, Tom; Keller, Stacia; Mishra, Umesh

2017-11-01

An improvement in the suppression of surface riding of magnesium from p-GaN:Mg into subsequent layers was achieved via low temperature flow modulation epitaxy. In particular, the slope of the Mg concentration drop was reduced to 5 nm/dec for a growth temperature of 620 °C — the lowest value ever reported for metalorganic chemical vapor deposition. The electrical quality of the top layer was verified by creating a two-dimensional electron gas on top of the buried p-GaN layer, which exhibited a mobility of 1300 cm2 V-1 s-1. In addition, layers grown using flow modulation epitaxy were shown to block the propagation of Mg more efficiently than samples in which an ex situ wet etch was used.

A Molecular Ni-complex Containing Tetrahedral Nickel Selenide Core as Highly Efficient Electrocatalyst for Water Oxidation.

PubMed

Masud, Jahangir; Ioannou, Polydoros-Chrysovalantis; Levesanos, Nikolaos; Kyritsis, Panayotis; Nath, Manashi

2016-11-23

We report the highly efficient catalytic activity of a transition metal selenide-based coordination complex, [Ni{(SeP i Pr 2 ) 2 N} 2 ], (1) for oxygen evolution and hydrogen evolution reactions (OER and HER, respectively) in alkaline solution. Very low overpotentials of 200 mV and 310 mV were required to achieve 10 mA cm -2 for OER and HER, respectively. The overpotential for OER is one of the lowest that has been reported up to now, making this one of the best OER electrocatalysts. In addition, this molecular complex exhibits an exceptionally high mass activity (111.02 A g -1 ) and a much higher TOF value (0.26 s -1 ) at a overpotential of 300 mV. This bifunctional electrocatalyst enables water electrolysis in alkaline solutions at a cell voltage of 1.54 V. © 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Characterization and spatial distribution of mangrove forest types based on ALOS-PALSAR mosaic 25m-resolution in Southeast Asia

NASA Astrophysics Data System (ADS)

Darmawan, S.; Takeuchi, W.; Nakazono, E.; Parwati, E.; Dien, V. T.; Oo, K. S.; Wikantika, K.; Sari, D. K.

2016-06-01

The objective of this research is to investigate characteristics of mangrove forest types and to identify spatial distribution of mangrove forest based on ALOS PALSAR mosaic 25m- resolution in Southeast Asia. Methodology consists of collecting of ALOS PALSAR image for overall Southeast Asia region, preprocessing include converting DN to NRCS and filtering, collecting regions of interest of mangrove forest in Southeast Asia, plotting, characterization and classification. Result on this research we found characteristics of mangrove forest on HH values around -10.88 dB to -6.65 dB and on HV value around -16.49 dB to -13.26 dB. On polarization of HH which the highest backscattering value is mangrove forest in Preak Piphot River Cambodia, Thái Thủy Thai Binh Vietnam, and Vạn Ninh tp. Móng Cái Quảng Ninh Vietnam whereas the lowest backscattering value is mangrove forest in Thailand area. On polarization of HV which the highest backscattering value is mangrove forest in Preak Piphot River Cambodia, Sorong and Teluk Bintuni Indonesia whereas the lowest backscattering value is mangrove forest in Subang Indonesia, Giao Thiện Giao Thuỷ Nam Định, Vietnam and Puyu Mueng Satun Thailand. Based on characterization, we create a rule criteria for classification of mangrove areas and non mangrove area. Finally we found spatial distribution of mangrove forest based on ALOS PALSAR 25m-resolution in Southeast Asia.

Reconfiguring redundancy management

NASA Technical Reports Server (NTRS)

Gelderloos, H. J. C. (Inventor)

1982-01-01

A redundancy management system is described wherein input signals from a sensor are provided redundantly in parallel so that a primary control signal may be selected. Median value signals for groups of three sensors are detected in median value selectors of selection filter. The detected median value signals are then also compared in a subtractor/comparator to determine whether any of them exceed the others by an amount greater than the signal level for a failed sensor. If so, the exceeding detected medium value signal is sent to a control computer as the primary control signal. If not, the lowest level detected medium value signal is sent as the primary control signal.

Estimating procedure for major highway construction bid item cost : final report.

DOT National Transportation Integrated Search

1978-06-01

The present procedure for estimating construction bid item cost makes use of the quarterly weighted average unit price report coupled with engineering judgement. The limitation to this method is that this report format provides only the lowest bid da...

Diffusion-weighted magnetic resonance imaging using different b-value combinations for the evaluation of treatment results after volumetric MR-guided high-intensity focused ultrasound ablation of uterine fibroids.

PubMed

Ikink, Marlijne E; Voogt, Marianne J; van den Bosch, Maurice A A J; Nijenhuis, Robbert J; Keserci, Bilgin; Kim, Young-sun; Vincken, Koen L; Bartels, Lambertus W

2014-09-01

To assess the value of diffusion-weighted magnetic resonance imaging (DWI) and apparent diffusion coefficient (ADC) mapping using different b-value combinations for treatment evaluation after magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) of uterine fibroids. Fifty-six patients with 67 uterine fibroids were treated with volumetric MR-HIFU. Pre-treatment and post-treatment images were obtained using contrast-enhanced T1-weighted MRI (CE-T1WI) and DWI using b = 0, 200, 400, 600, 800 s/mm(2). ADC maps were generated using subsets of b-values to investigate the effects of tissue ablation on water diffusion and perfusion in fibroids treated with MR-HIFU. Four combinations of b-values were used: (1) all b-values; (2) b = 0, 200 s/mm(2); (3) b = 400, 600, 800 s/mm(2); and (4) b = 0, 800 s/mm(2). Using the lowest b-values (0 and 200 s/mm(2)), the mean ADC value in the ablated tissue reduced significantly (p < 0.001) compared with baseline. Calculating the ADC value with the highest b-values (400, 600, 800 s/mm(2)), the ADC increased significantly (p < 0.001) post-treatment. ADC maps calculated with the lowest b-values resulted in the best visual agreement of non-perfused fibroid tissue detected on CE images. Other b-value combinations and normal myometrium showed no difference in ADC after MR-HIFU treatment. A decrease in contrast agent uptake within the ablated region on CE-T1WI was correlated to a significantly decreased ADC when b = 0 and 200 s/mm(2) were used. DWI could be useful for treatment evaluation after MR-HIFU of uterine fibroids. The ADC in fibroid tissue is influenced by the choice of b- values. Low b-values seem the best choice to emphasise perfusion effects after MR-HIFU.

Grazing Impact of the Copepod Calanus sinicus on Phytoplankton in the Northern East China Sea in Late Spring

NASA Astrophysics Data System (ADS)

Kim, Garam; Kang, Hyung-Ku

2018-03-01

We investigated the feeding habits of Calanus sinicus during its four developmental stages as copepodite 4 (CIV), copepodite 5 (CV), adult males and females in early June 2015 at 12 sampling stations along the southern coast of Korea to the northern East China Sea, to better understand the role of C. sinicus in controlling phytoplankton stocks. Ingestion rate, daily ration as body carbon, population ingestion rate, and grazing impact were estimated using the gut pigment method. The mean biomass of CVs was the greatest (13.5 mg C m-3) and that of adult males was the lowest (0.7 mg C m-3). The ingestion rate per C. sinicus individual tended to increase with developmental stage, with the highest rate in adult females (519 ng chl ind-1 d-1) and the lowest rate in CIVs (305 ng chl ind-1 d-1). A significant correlation was found between ingestion rate and temperature, but not salinity or chlorophyll-a concentration. The daily ration of C. sinicus as body carbon significantly decreased with increased body weight, with the highest value found in CIVs (66.4%) and the lowest value in adult males (30%). Despite the high ingestion rate of the adults, the mean grazing impact of C. sinicus on phytoplankton biomass, in terms of chlorophyll-a concentration, was the highest in CVs (2.6%), followed by CIVs and adult females, and was the lowest in adult males (0.1%). The higher grazing impact of copepodites than adults underscores the importance of evaluating copepodite stages in the feeding studies of marine food webs.

The Effect of Herbaceous Legume of Feed in In-Vitro Digestibility

NASA Astrophysics Data System (ADS)

Ratnawaty, S.; Hartutik; Chuzaemi, S.

2018-02-01

This study was carried out to evaluate in-vitro digestibility of herbal legumesin feed. The materials used in this study were three types of herbal legumes namely Clitoria ternatea Q5455 (CT Q5455), Clitoria ternatea cv. Milgarra (CT cv Milgarra) and Stylosanthes seabrana (S. seabrana), The treatments were P0 = 100% Grass; P1 = 50% Grass+ 50% CT Q5455, P2 = 50% Grass + 50% CT cv. Milgarra, P3 = 50% Grass + 50% S. seabrana. The result showed that the treatments had a significant effect (P <0.05). The highest dry matter (DM) digestibilitywas in P1 (60.35%) and P3 (60.22%). The DM digestibility of the highest raw materials was in CT cv. Milgarra (73.49%) and the lowest one was in S. seabrana (63.90%). The treatments had a very significant effect (P <0.01) on the organic matter (OM) Digestibility. The highest OM digestibility wasin P1 (63.04%) and P3 (61.89%). The highest value of OM digestibility of raw materials was in CT cv. Milgarra (73.90%) and the lowest one was in S. seabrana (63.85%). The treatmentshad a significant effect (P <0.05) on the crude protein (CP) digestibility. The average CP digestibility of feed was at the same value in all treatments but in CT Q5455 (67.25%). The treatmentshad a significant effect (P <0.05) on the total digestible nutrients (TDN). The highest TDN was in P1 (66.19%) and the lowest one was in P0 (51.38%). Average TDN of the highest raw material was in CT cv. Milgarra (77.59%) and the lowest was in S. seabrana (67.04%).

Fundamental supply of skin blood flow in the Chinese Han population: Measurements by a full-field laser perfusion imager.

PubMed

Fei, W; Xu, S; Ma, J; Zhai, W; Cheng, S; Chang, Y; Wang, X; Gao, J; Tang, H; Yang, S; Zhang, X

2018-05-08

Skin blood flow is believed to link with many diseases, and shows a significant heterogeneity. There are several papers on basal cutaneous microcirculation perfusion in different races, while the data in Chinese is vacant. The aim was to establish the database of absolute fundamental supply of skin blood flow in the Chinese Han population. With a full-field laser perfusion imager (FLPI), the skin blood flow can be quantified. Cutaneous perfusion values were determined in 17 selected skin areas in 406 healthy participants aged between 20 and 80 years (mean 35.05 ± 11.33). Essential parameters such as weight, height were also measured and values of BMI were calculated. The perfusion values were reported in Arbitrary Perfusion Units (APU). The highest cutaneous perfusion value fell on eyelid (931.20 ± 242.59 in male and 967.83 ± 225.49 in female), and pretibial had the lowest value (89.09 ± 30.28 in male and 85.08 ± 33.59 in female). The values were higher in men than women on the bank of fingertips, nose, forehead, cheek, neck and earlobe (P < .05). Perfusion values on stretch and flexion side of forearm had negative correlation with age (P = .01 and P = 4.88 × 10 -3 , respectively) in male. Abdomen was negatively correlated with BMI in both gender (P = .02, respectively). Skin blood flow values vary with skin regions. There is a tendency to measure higher perfusion values in men than in women. And the values are irrelevant with age or BMI. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Copper complexation capacity in surface waters of the Venice Lagoon.

PubMed

Delgadillo-Hinojosa, Francisco; Zirino, Alberto; Nasci, Cristina

2008-10-01

Total copper (Cu(T)), copper ion activity (pCu) and the copper complexation capacity (CuCC) were determined in samples of seawater collected in July 2003 from the Venice Lagoon. Cu(T) and CuCC showed considerable spatial variability: Cu(T) ranged from 1.8 to 70.0nM, whereas the CuCC varied from 195 to 573nM. pCu values varied from 11.6 to 12.6 and are consistent with those previously reported in estuarine and coastal areas (10.9-14.1). The range of Cu(T) values compares well with those reported in the past in the lagoon and in the adjacent Adriatic Sea. The highest concentrations of Cu(T) were found in samples collected near the industrial area of Porto Marghera, whereas the lowest were measured near the Chioggia and Malamocco inlets, where an intense tidally-driven renewal of seawater takes place. Although CuCC showed a high degree of spatial variability, the values recorded in the Venice Lagoon are comparable to those reported in other estuarine systems. In addition, CuCC was positively correlated with dissolved organic carbon (DOC), suggesting that organic ligands responsible for Cu complexation are part of the bulk organic matter pool in the lagoon. The CuCC:Cu(T) molar ratio was, on average 55:1, indicating that a large excess of complexation capacity exists in the Venice Lagoon. The high levels of CuCC and the narrow range of pCu indicates the importance of the role played by organic ligands in controlling the free ion Cu concentrations in the lagoon, and as a consequence, regulating its availability and/or toxicity.

Microbiological and chemical properties of litter from different chicken types and production systems.

PubMed

Omeira, N; Barbour, E K; Nehme, P A; Hamadeh, S K; Zurayk, R; Bashour, I

2006-08-15

Chicken litter is produced in large quantities from all types of poultry raising activities. It is primarily used for land application, thus it is essential to analyze its properties before it is released to the environment. The objective of this study is to compare the microbiological and chemical properties of litter generated from layer and broiler chickens reared under intensive and free-range production systems. The microbiological analysis consisted of the enumeration of total bacteria, total coliforms, Staphylococcus species, Salmonella species and Clostridium perfringens. Chicken litter from layers reared under intensive and free range systems showed lower mean total bacterial count than the litter collected from chicken broilers reared under either of the two systems (P=0.0291). The litter from intensive layers had the lowest mean total coliform counts (P=0.0222) while the lowest Staphylococcus species count was observed in the litter from free-range layers (P=0.0077). The C. perfringens count was the lowest in chicken litter from intensively raised broilers and layers (P=0.0001). The chemical properties of litter from the different chicken types and production systems were compared based on determination of pH, electrical conductivity, carbon, nitrogen, phosphorus, potassium, cadmium and zinc. Litter from free-range broilers showed the highest pH value (P=0.0005); however, the electrical conductivity was higher in the litter from both intensive and free-range layers compared to the litter from both broiler production systems (P=0.0117). Chicken litter from intensive systems had higher nitrogen content than litter from free-range systems (P=0.0000). The total phosphorus was the lowest in free-range broiler litter (P=0.0001), while the total potassium was the lowest in litter from intensively managed broilers (P=0.0000). Zinc appeared higher in litter from layers compared to that from broilers (P=0.0101). The cadmium content was higher in the litter from free-range broilers and layers compared to that in the litter from intensively managed systems (P=0.0439). Staphylococcus species in the litter as well as cadmium concentrations seem to be the most critical parameters presenting risks on the environment and on human health. Based on the lowest coliform counts (an indication of water pollution), the high nutrient levels and the low cadmium values, litter from intensively managed layers appears as the most suitable for application on agricultural soils.

Acoustic radiation force impulse (ARFI) elastography for detection of renal damage in children.

PubMed

Göya, Cemil; Hamidi, Cihad; Ece, Aydın; Okur, Mehmet Hanifi; Taşdemir, Bekir; Çetinçakmak, Mehmet Güli; Hattapoğlu, Salih; Teke, Memik; Şahin, Cahit

2015-01-01

Acoustic radiation force impulse (ARFI) imaging is a promising method for noninvasive evaluation of the renal parenchyma. To investigate the contribution of ARFI quantitative US elastography for the detection of renal damage in kidneys with and without vesicoureteral reflux (VUR). One hundred seventy-six kidneys of 88 children (46 male, 42 female) who had been referred for voiding cystourethrography and 20 healthy controls were prospectively investigated. Patients were assessed according to severity of renal damage on dimercaptosuccinic acid (DMSA) scintigraphy. Ninety-eight age- and gender-matched healthy children constituted the control group. Quantitative shear wave velocity (SWV) measurements were performed in the upper and lower poles and in the interpolar region of each kidney. DMSA scintigraphy was performed in 62 children (124 kidneys). Comparisons of SWV values of kidneys with and without renal damage and/or VUR were done. Significantly higher SWV values were found in non-damaged kidneys. Severely damaged kidneys had the lowest SWV values (P < 0.001). High-grade (grade V-IV) refluxing kidneys had the lowest SWV values, while non-refluxing kidneys had the highest values (P < 0.05). Significant negative correlations were found between the mean quantitative US elastography values and DMSA scarring score (r = -0.788, P < 0.001) and VUR grade (r = -0.634, P < 0.001). SWV values of the control kidneys were significantly higher than those of damaged kidneys (P < 0.05). Our findings suggest decreasing SWV of renal units with increasing grades of vesicoureteric reflux, increasing DMSA-assessed renal damage and decreasing DMSA-assessed differential function.

Earthquake hazard analysis for the different regions in and around Aǧrı

NASA Astrophysics Data System (ADS)

Bayrak, Erdem; Yilmaz, Şeyda; Bayrak, Yusuf

2016-04-01

We investigated earthquake hazard parameters for Eastern part of Turkey by determining the a and b parameters in a Gutenberg-Richter magnitude-frequency relationship. For this purpose, study area is divided into seven different source zones based on their tectonic and seismotectonic regimes. The database used in this work was taken from different sources and catalogues such as TURKNET, International Seismological Centre (ISC), Incorporated Research Institutions for Seismology (IRIS) and The Scientific and Technological Research Council of Turkey (TUBITAK) for instrumental period. We calculated the a value, b value, which is the slope of the frequency-magnitude Gutenberg-Richter relationship, from the maximum likelihood method (ML). Also, we estimated the mean return periods, the most probable maximum magnitude in the time period of t-years and the probability for an earthquake occurrence for an earthquake magnitude ≥ M during a time span of t-years. We used Zmap software to calculate these parameters. The lowest b value was calculated in Region 1 covered Cobandede Fault Zone. We obtain the highest a value in Region 2 covered Kagizman Fault Zone. This conclusion is strongly supported from the probability value, which shows the largest value (87%) for an earthquake with magnitude greater than or equal to 6.0. The mean return period for such a magnitude is the lowest in this region (49-years). The most probable magnitude in the next 100 years was calculated and we determined the highest value around Cobandede Fault Zone. According to these parameters, Region 1 covered the Cobandede Fault Zone and is the most dangerous area around the Eastern part of Turkey.

Agreement between children and parents demonstrated that illness-related absenteeism was validly reported by children.

PubMed

Denbæk, Anne Maj; Bonnesen, Camilla Thørring; Andersen, Anette; Holstein, Bjørn Evald; Laursen, Bjarne; Due, Pernille; Johansen, Anette

2016-01-01

To examine the agreement between children's and parents' reporting of illness-related absenteeism from school and to examine predictors for disagreement between children and parents. A total of 8,438 schoolchildren aged from 5 to 15 years (grade 0-8) and one parent of each child were invited to participate in the Hi Five baseline study. The response rate for children answering a questionnaire was 89% (n = 7,525), and 36% of the parents (n = 3,008) participated in a weekly illness registration study using text messages (short message service) over a period of 22 weeks. Text messages and questionnaire data were linked at the individual level, leaving 2,269 child-parent pairs in the analysis, corresponding to 27% of the eligible sample. The agreement between children's and parents' reports of illness-related absenteeism was good, with high absolute agreement and slight to moderate Ƙ values. Agreement was lowest for 6- to 8-year-olds and highest for 11- to 12-year-olds. Children's reports of illness symptoms and parents' reports of their children's illnesses in the preceding week were strong predictors for children reporting illness-related absenteeism when parents did not. Illness-related absenteeism can be reported by children, and children report higher prevalence of illness-related absenteeism than parents. Copyright © 2016 Elsevier Inc. All rights reserved.

Microstructure, Pitting Corrosion Resistance and Impact Toughness of Duplex Stainless Steel Underwater Dry Hyperbaric Flux-Cored Arc Welds

PubMed Central

Hu, Yu; Shen, Xiao-Qin; Wang, Zhong-Min

2017-01-01

Duplex stainless steel multi-pass welds were made at 0.15 MPa, 0.45 MPa, and 0.75 MPa pressure, simulating underwater dry hyperbaric welding by the flux-cored arc welding (FCAW) method, with welds of normal pressure as a benchmark. The purpose of this work was to estimate the effect of ambient pressure on the microstructure, pitting corrosion resistance and impact toughness of the weld metal. The microstructure measurement revealed that the ferrite content in the weld metal made at 0.45 MPa is the lowest, followed by that of 0.75 MPa and 0.15 MPa. The analysis of potentiodynamic polarization tests at 30 °C and 50 °C demonstrated that the pitting corrosion resistance depends on the phases of the lower pitting resistance equivalent numbers (PREN), secondary austenite and ferrite. The weld metal made at 0.45 MPa had the best resistance to pitting corrosion at 30 °C and 50 °C with the highest PRENs of secondary austenite and ferrite. The weld metal made at 0.15 MPa displayed the lowest pitting corrosion resistance at 30 °C with the lowest PREN of secondary austenite, while the weld metal made at 0.75 MPa was the most seriously eroded after being tested at 50 °C for the lowest PREN of ferrite, with large cluster pits seen in ferrite at 50 °C. The impact tests displayed a typical ductile-brittle transition because of the body-centered cubic (BCC) structure of the ferrite when the test temperature was lowered. All the weld metals met the required value of 34 J at −40 °C according to the ASTM A923. The highest ferrite content corresponded to the worst impact toughness, but the highest toughness value did not correspond to the greatest austenite content. With the decreasing of the test temperature, the drop value of absorbed energy was correlated to the ferrite content. Additionally, in this work, the weld metal made at 0.45 MPa had the best combined properties of pitting resistance and impact toughness. PMID:29258262

Microstructure, Pitting Corrosion Resistance and Impact Toughness of Duplex Stainless Steel Underwater Dry Hyperbaric Flux-Cored Arc Welds.

PubMed

Hu, Yu; Shi, Yong-Hua; Shen, Xiao-Qin; Wang, Zhong-Min

2017-12-18

Duplex stainless steel multi-pass welds were made at 0.15 MPa, 0.45 MPa, and 0.75 MPa pressure, simulating underwater dry hyperbaric welding by the flux-cored arc welding (FCAW) method, with welds of normal pressure as a benchmark. The purpose of this work was to estimate the effect of ambient pressure on the microstructure, pitting corrosion resistance and impact toughness of the weld metal. The microstructure measurement revealed that the ferrite content in the weld metal made at 0.45 MPa is the lowest, followed by that of 0.75 MPa and 0.15 MPa. The analysis of potentiodynamic polarization tests at 30 °C and 50 °C demonstrated that the pitting corrosion resistance depends on the phases of the lower pitting resistance equivalent numbers (PREN), secondary austenite and ferrite. The weld metal made at 0.45 MPa had the best resistance to pitting corrosion at 30 °C and 50 °C with the highest PRENs of secondary austenite and ferrite. The weld metal made at 0.15 MPa displayed the lowest pitting corrosion resistance at 30 °C with the lowest PREN of secondary austenite, while the weld metal made at 0.75 MPa was the most seriously eroded after being tested at 50 °C for the lowest PREN of ferrite, with large cluster pits seen in ferrite at 50 °C. The impact tests displayed a typical ductile-brittle transition because of the body-centered cubic (BCC) structure of the ferrite when the test temperature was lowered. All the weld metals met the required value of 34 J at -40 °C according to the ASTM A923. The highest ferrite content corresponded to the worst impact toughness, but the highest toughness value did not correspond to the greatest austenite content. With the decreasing of the test temperature, the drop value of absorbed energy was correlated to the ferrite content. Additionally, in this work, the weld metal made at 0.45 MPa had the best combined properties of pitting resistance and impact toughness.

High resolution absorption spectrum of CO2between 1750 and 2000 Å. 2. Rotational analysis of two parallel-type bands assigned to the lowest electronic transition 13B2←

NASA Astrophysics Data System (ADS)

Cossart-Magos, Claudina; Launay, Françoise; Parkin, James E.

The absorption spectrum of CO2 gas between 175 and 200 nm was photographed at high resolution some years ago. This very weak spectral region proved to be extremely rich in bands showing rotational fine structure. In Part 1 [C. Cossart-Magos, F. Launay, J. E. Parkin, Mol. Phys., 75, 835 (1992), nine perpendicular-type bands were assigned to the lowest singlet-singlet transition, 11A2 ← ν'3 (b2) vibration. Here, the parallel-type bands observed at 185.7 and 175.6 nm are assigned to the lowest triplet-singlet transition, 13B2 ← TMPH0629math005 ν'2 (a1) vibration. The assignment and the rotational and spin constant values obtained are discussed in relation to previous experimental data and ab initio calculation results on the lowest excited states of CO2. The actual role of the 13B2 state in CO2 photodissociation, O(3P)+CO(X1Σ+) recombination, and O(1D) emission quenching by CO(X) molecules is reviewed.

[Foliar water use efficiency of Platycladus orientalis sapling under different soil water contents].

PubMed

Zhang, Yong E; Yu, Xin Xiao; Chen, Li Hua; Jia, Guo Dong; Zhao, Na; Li, Han Zhi; Chang, Xiao Min

2017-07-18

The determination of plant foliar water use efficiency will be of great value to improve our understanding about mechanism of plant water consumption and provide important basis of regional forest ecosystem management and maintenance, thus, laboratory controlled experiments were carried out to obtain Platycladus orientalis sapling foliar water use efficiency under five different soil water contents, including instantaneous water use efficiency (WUE gs ) derived from gas exchange and short-term water use efficiency (WUE cp ) caculated using carbon isotope model. The results showed that, controlled by stomatal conductance (g s ), foliar net photosynthesis rate (P n ) and transpiration rate (T r ) increased as soil water content increased, which both reached maximum va-lues at soil water content of 70%-80% field capacity (FC), while WUE gs reached a maximum of 7.26 mmol·m -2 ·s -1 at the lowest soil water content (35%-45% FC). Both δ 13 C of water-soluble leaf and twig phloem material achieved maximum values at the lowest soil water content (35%-45% FC). Besides, δ 13 C values of leaf water-soluble compounds were significantly greater than that of phloem exudates, indicating that there was depletion in 13 C in twig phloem compared with leaf water-soluble compounds and no obvious fractionation in the process of water-soluble material transportation from leaf to twig. Foliar WUE cp also reached a maximum of 7.26 mmol·m -2 ·s -1 at the lowest soil water content (35%-45% FC). There was some difference between foliar WUE gs and WUE cp under the same condition, and the average difference was 0.52 mmol·m -2 ·s -1 . The WUE gs had great space-time variability, by contrast, WUE cp was more representative. It was concluded that P. orientalis sapling adapted to drought condition by increasing water use efficiency and decreasing physiological activity.

Consumer Attitudes Toward Storing and Thawing Chicken and Effects of the Common Thawing Practices on Some Quality Characteristics of Frozen Chicken

PubMed Central

Benli, Hakan

2016-01-01

In this study, a survey was conducted to both evaluate the consumers’ general attitudes for purchasing and storing the raw chicken and determine the thawing practices used for defrosting frozen chicken at home. About 75% of the consumers indicated purchasing chicken meat at least once a week or more. Furthermore, the majority (82.16%) of those who stored at least a portion of the raw chicken stated freezing the raw chicken meat at home. Freezing the chicken meat was considered to have no effect on the quality by 43.49% of the consumers while 56.51% thought that freezing had either negative or positive effects on the quality. The survey study indicated that top five most commonly used thawing practices included thawing on the kitchen counter, thawing in the refrigerator, thawing in the warm water, thawing in the microwave, and thawing under tap water. In addition, an experimental study was conducted to determine the effects of these most commonly used thawing practices on some quality characteristics of the chicken meat including pH, drip loss, cooking loss, color analysis and textural profile analysis. Although, L* value for thawing on the kitchen counter was the lowest, after cooking, none of the thawing treatments have a significant effect on the color values. Thawing in the microwave produced the highest drip loss of 3.47% while the lowest drip loss of 0.62% was observed with thawing in the refrigerator. On the other hand, thawing in the microwave and refrigerator caused the lowest cooking loss values of 18.29% and 18.53%, respectively. Nevertheless, there were no significant differences among textural parameter values of the defrosted and then cooked samples using the home based thawing practices, indicating similar quality characteristics among the samples. PMID:26732333

Heat resistance of thermoduric enterococci isolated from milk.

PubMed

McAuley, Catherine M; Gobius, Kari S; Britz, Margaret L; Craven, Heather M

2012-03-15

Enterococci are reported to survive pasteurisation but the extent of their survival is unclear. Sixty-one thermoduric enterococci isolates were selected from laboratory pasteurised milk obtained from silos in six dairy factories. The isolates were screened to determine log(10) reductions incurred after pasteurisation (63°C/30 min) and ranked from highest to lowest log(10) reduction. Two isolates each of Enterococcus faecalis, Enterococcus faecium, Enterococcus durans and Enterococcus hirae, exhibiting the median and the greatest heat resistance, as well as E. faecalis ATCC 19433, were selected for further heat resistance determinations using an immersed coil apparatus. D values were calculated from survival curves plotted from viable counts obtained after heating isolates in Brain Heart Infusion Broth at 63, 69, 72, 75 and 78°C followed by rapid cooling. At 72°C, the temperature employed for High Temperature Short Time (HTST) pasteurisation (72°C/15s), the D values extended from 0.3 min to 5.1 min, depending on the isolate and species. These data were used to calculate z values, which ranged from 5.0 to 9.8°C. The most heat sensitive isolates were E. faecalis (z values 5.0, 5.7 and 7.5°C), while the most heat resistant isolates were E. durans (z values 8.7 and 8.8°C), E. faecium (z value 9.0°C) and E. hirae (z values 8.5 and 9.8°C). The data show that heat resistance in enterococci is highly variable. Copyright © 2011 Elsevier B.V. All rights reserved.

Tribological characteristics of perfluoropolyether liquid lubricants under sliding conditions in high vacuum

NASA Technical Reports Server (NTRS)

Masuko, Masabumi; Jones, William R., Jr.; Helmick, Larry S.

1993-01-01

Tribological characteristics of three PFPE's (Fomblin Z, Demnum, and Krytox) were studied under high vacuum using a four-ball apparatus with 440C steel specimens. Fomblin Z and Demnum exhibited initial scuffing-like high friction whereas Krytox did not. Steady state friction with Fomblin Z was the lowest among the three oils. Frictional values for Demnum and Krytox were almost the same. The lowest wear rate in air was provided by Krytox regardless of load, and low wear rates in vacuum at high load were achieved with Krytox and Demnum. Results are explained by reactivity and pressure-viscosity characteristics of the oils.

Phase Formation and Superconductivity of Fe-TUBE Encapsulated and Vacuum-Annealed MgB2

NASA Astrophysics Data System (ADS)

Singh, K. P.; Awana, V. P. S.; Shahabuddin, Md.; Husain, M.; Saxena, R. B.; Nigam, Rashmi; Ansari, M. A.; Gupta, Anurag; Narayan, Himanshu; Halder, S. K.; Kishan, H.

We report optimization of the synthesis parameters viz. heating temperature (TH), and hold time (thold) for vacuum-annealed (10-5 Torr) and LN2 (liquid nitrogen) quenched MgB2 compound. These are single-phase compounds crystallizing in the hexagonal structure (space group P6/mmm) at room temperature. Our XRD results indicated that for phase-pure MgB2, the TH for 10-5 Torr annealed and LN2-quenched samples is 750°C. The right stoichiometry i.e., MgB2 of the compound corresponding to 10-5 Torr and TH of 750°C is found for the hold time (thold) of 2.30 hours. With varying thold from 1-4 hours at fixed TH (750°C) and vacuum (10-5 Torr), the c-lattice parameter decreases first and later increases with thold (hours) before a near saturation, while the a-lattice parameter first increases and later decreases beyond a thold of 2.30 hours. The c/a ratio versus thold plot showed an inverted bell-shaped curve, touching the lowest value of 1.141, which is the reported value for perfect stoichiometry of MgB2. The optimized stoichimetric MgB2 compound exhibited superconductivity at 39.2 K with a transition width of 0.6 K. In conclusion, the synthesis parameters for phase pure stoichimetric vacuum-annealed MgB2 compound are optimized and are compared with widely-reported Ta tube encapsulated samples.

Children of divorce-coping with divorce: A randomized control trial of an online prevention program for youth experiencing parental divorce.

PubMed

Boring, Jesse L; Sandler, Irwin N; Tein, Jenn-Yun; Horan, John J; Vélez, Clorinda E

2015-10-01

Evaluate an online coping skills program to prevent mental health problems in children and adolescents from divorced or separated families. Children ages 11-16 (N = 147) whose families had filed for divorce were recruited using public court records. Participants were blocked by risk-score and randomly assigned to either a control (Internet self-study condition, Best of the Net (BTN) or the experimental intervention, Children of Divorce-Coping With Divorce (CoD-CoD), a 5-module highly interactive online program to promote effective coping skills. Program effects were tested on measures of children's self-reported coping and parent and youth reports of children's mental health problems. Significant main effects indicated that youth in CoD-CoD improved more on self-reported emotional problems relative to BTN youth (d = .37) and had a lower rate of clinically significant self-reported mental health problems (OR = .58, p = .04). A significant Baseline × Treatment interaction indicated that the 55% of youth with highest baseline problems improved more than those in BTN on their self-report of total mental health problems. A significant interaction effect indicated that CoD-CoD improved youth coping efficacy for the 30% of those with the lowest baseline coping efficacy. For the 10% of youth with lowest parent-reported risk at baseline, those who received BTN had lower problems than CoD-CoD participants. CoD-CoD was effective in reducing youth-reported mental health problems and coping efficacy particularly for high risk youth. Parent-report indicated that, relative to BTN, CoD-CoD had a negative effect on mental health problems for a small group with the lowest risk. (c) 2015 APA, all rights reserved).

Comment on "Atomic structure calculations and identification of EUV and SXR spectral lines in Sr XXX" by A. Goyal, I. Khatri, S. Aggarwal, A.K. Singh, M. Mohan [J Quant Spectrosc Radiat Transf 2015;161:157

NASA Astrophysics Data System (ADS)

Aggarwal, Kanti M.

2015-11-01

Recently, Goyal et al. [1] reported energies and lifetimes (τ) for the lowest 113 levels of the 2s22p5, 2s2p6, 2s22p43ℓ, 2s2p53ℓ and 2p63ℓ configurations of F-like Sr XXX. For the calculations they adopted the multi-configuration Dirac-Fock (MCDF) and the flexible atomic code (FAC). Additionally, they also listed radiative rates (A- values), oscillator strengths (f- values) and line strengths (S- values) for four types of transitions, namely electric dipole (E1), electric quadrupole (E2), magnetic dipole (M1) and magnetic quadrupole (M2), but only from the ground to the higher excited levels. However, there are two clear anomalies in their reported data. Firstly, the f-values listed from FAC in their Tables 3-6 are larger than from MCDF by a factor of two, for all transitions. This is because they have blindly listed the output from FAC without realising that, unlike MCDF, FAC lists ωf where ω is the statistical weight, and happens to be exactly 2 in the present case. Secondly, their lifetime for level 2 (2s22p51/2 o 2P) is incorrect. This is because the dominant contributing transition for this level is 1-2 M1 for which A=3.25×106 s-1, listed (correctly) in their Table 5, and this leads to τ=3.08×10-7 s, and not 1.54×10-7 s, as listed in their Table 1.

Health-related quality of life in Indian children: A community-based cross-sectional survey

PubMed Central

Raj, Manu; Sudhakar, Abish; Roy, Rinku; Champaneri, Bhavik; Joy, Teena Mary; Kumar, Raman Krishna

2017-01-01

Background & objectives: There are limited data on health-related quality of life (HRQOL) related to Indian children. The objective of this study was to construct a generic HRQOL reference for children aged 2-18 yr from a community setting. Methods: The study was a community-based cross-sectional survey. A total of 719 children/adolescents in the age group of 2-18 yr were enrolled using stratified random cluster sampling. A total of 40 clusters (cluster size 18) were selected for the study. The data contained child self-report and parent proxy report from healthy children and their parents/caretakers. The Pediatric Quality of Life Inventory 4.0 (PedsQL4.0) Generic Core Scale was used to collect HRQOL data. Questionnaires were self-administered for parents and children aged 8-18 yr. In the age group of five to seven years, parents assisted the children in filling questionnaires. Results: The mean HRQOL total scores from child self-report and parent proxy report were 87.50±11.10 and 90.10±9.50 respectively, for children aged 2-18 yr. Social functioning had the highest scores and emotional functioning had the lowest scores for the entire sample and subgroups. The mean values for HRQOL in the current study were significantly different from the reference study for both child (87.39 vs. 83.91, P<0.001) and parent proxy reports (90.03 vs. 82.29, P<0.001) when compared between children aged 2-16 yr. Interpretation & conclusions: The study provided reference values for HRQOL in healthy children and adolescents from Kerala, India, that appeared to be different from existing international reference. Similar studies need to be done in different parts of India to generate a country-specific HRQOL reference for Indian children. PMID:28862185

Level of Agreement and Factors Associated With Discrepancies Between Nationwide Medical History Questionnaires and Hospital Claims Data.

PubMed

Kim, Yeon-Yong; Park, Jong Heon; Kang, Hee-Jin; Lee, Eun Joo; Ha, Seongjun; Shin, Soon-Ae

2017-09-01

The objectives of this study were to investigate the agreement between medical history questionnaire data and claims data and to identify the factors that were associated with discrepancies between these data types. Data from self-reported questionnaires that assessed an individual's history of hypertension, diabetes mellitus, dyslipidemia, stroke, heart disease, and pulmonary tuberculosis were collected from a general health screening database for 2014. Data for these diseases were collected from a healthcare utilization claims database between 2009 and 2014. Overall agreement, sensitivity, specificity, and kappa values were calculated. Multiple logistic regression analysis was performed to identify factors associated with discrepancies and was adjusted for age, gender, insurance type, insurance contribution, residential area, and comorbidities. Agreement was highest between questionnaire data and claims data based on primary codes up to 1 year before the completion of self-reported questionnaires and was lowest for claims data based on primary and secondary codes up to 5 years before the completion of self-reported questionnaires. When comparing data based on primary codes up to 1 year before the completion of self-reported questionnaires, the overall agreement, sensitivity, specificity, and kappa values ranged from 93.2 to 98.8%, 26.2 to 84.3%, 95.7 to 99.6%, and 0.09 to 0.78, respectively. Agreement was excellent for hypertension and diabetes, fair to good for stroke and heart disease, and poor for pulmonary tuberculosis and dyslipidemia. Women, younger individuals, and employed individuals were most likely to under-report disease. Detailed patient characteristics that had an impact on information bias were identified through the differing levels of agreement.

Health-related quality of life in Indian children: A community-based cross-sectional survey.

PubMed

Raj, Manu; Sudhakar, Abish; Roy, Rinku; Champaneri, Bhavik; Joy, Teena Mary; Kumar, Raman Krishna

2017-04-01

There are limited data on health-related quality of life (HRQOL) related to Indian children. The objective of this study was to construct a generic HRQOL reference for children aged 2-18 yr from a community setting. The study was a community-based cross-sectional survey. A total of 719 children/adolescents in the age group of 2-18 yr were enrolled using stratified random cluster sampling. A total of 40 clusters (cluster size 18) were selected for the study. The data contained child self-report and parent proxy report from healthy children and their parents/caretakers. The Pediatric Quality of Life Inventory 4.0 (PedsQL4.0) Generic Core Scale was used to collect HRQOL data. Questionnaires were self-administered for parents and children aged 8-18 yr. In the age group of five to seven years, parents assisted the children in filling questionnaires. The mean HRQOL total scores from child self-report and parent proxy report were 87.50±11.10 and 90.10±9.50 respectively, for children aged 2-18 yr. Social functioning had the highest scores and emotional functioning had the lowest scores for the entire sample and subgroups. The mean values for HRQOL in the current study were significantly different from the reference study for both child (87.39 vs. 83.91, P<0.001) and parent proxy reports (90.03 vs. 82.29, P<0.001) when compared between children aged 2-16 yr. The study provided reference values for HRQOL in healthy children and adolescents from Kerala, India, that appeared to be different from existing international reference. Similar studies need to be done in different parts of India to generate a country-specific HRQOL reference for Indian children.

Application Values of T-SPOT.TB in Clinical Rapid Diagnosis of Tuberculosis.

PubMed

Zhu, Feng; Ou, Qinfang; Zheng, Jian

2018-01-01

This paper aims to explore the application value of tuberculosis-specific enzyme-linked immunospot assay (T-SPOT.TB) in the diagnosis of tuberculosis. Fifty one patients with tuberculosis (TB) admitted to Wuxi No.5 People's Hospital, Wuxi, China from June 2015 to June 2017 were selected as the TB group, and 40 patients without tuberculosis admitted in the same period were randomly selected as the non-TB group. Patients in the two groups received T-SPOT.TB, TB antibody (TB-Ab) test and mycobacterium TB deoxyribonucleic acid (TB-DNA) test, and the results were compared. Comparisons of the sensitivity of the three methods showed that the sensitivity of T-SPOT.TB was the highest, followed by TB-DNA from sputum samples, and that of TB-Ab was the lowest. The specificity of TB-Ab was the highest, followed by T-SPOT.TB, and that of TB-DNA from sputum samples was the lowest. In the receiver operating characteristic (ROC) curve analysis, the area under curve (AUC) of T-SPOT.TB (0.896) was the highest, followed by TB-DNA from sputum samples (0.772), and that of sputum smears (0.698) was the lowest. T-SPOT.TB can quickly and accurately determine the presence of tuberculosis infection, and it is a non-invasive examination, which can further assist in the diagnosis and guide the treatment.

Choose Wisely: the Quality of Massage Education in the United States

PubMed Central

Menard, Martha Brown

2014-01-01

Background Assessing the quality of postsecondary education remains a difficult task, despite many efforts to do so. No consensus or standard definition of educational quality has yet been agreed upon or developed. Purpose This study evaluated the quality of massage education in the United States using three closely-related questions to frame the evaluation: 1) Is accreditation improving the quality of education for massage therapy? If not, then what do we need to do to improve it? 2) Does accreditation by COMTA specifically improve quality of education compared to other vocational accrediting agencies that do not require curriculum competencies specific to massage? 3) Would adding competencies at an “advanced” level, or specific degree levels, be helpful in advancing massage therapy in the eyes of other health professions? Setting United States Participants Members of a national massage education organization, members affiliated with the educational arm of two national professional associations, and members of two national education organizations in complementary and integrative health care (CIHC). Research Design Mixed methods evaluation using three data sources: existing gainful employment data from the US Department of Education, analyzed by type of massage program and accreditation agency to determine average and relative value for cost; numbers of disciplinary actions against massage practitioners reported by state regulatory agencies, and a qualitatively developed survey administered to two different groups of educators. Results Average tuition cost across all reporting schools/programs was $13,605, with an average graduation rate of 71.9%. Of the schools and programs that reported student loan data, 84% of students received federal financial aid. Median loan amount was $8,052, with an average repayment rate of 43.4%. Programs in corporate-owned schools had the highest average cost, highest median loan amount, and lowest repayment rate, while community college programs had the lowest average cost, lowest graduation rate, and lowest median loan amount. Repayment rate data were not available for community colleges. Of the five states and the District of Columbia that require school accreditation, there were 208 disciplinary actions from 2009–2011. The remaining 28 regulated states that do not require school accreditation reported 1,702 disciplinary actions during the same period. Seventy-five percent of massage educators and 58% of CIHC educators stated that the current quality of massage education is inconsistent, with only 10% of massage educators and 8% of CIHC educators agreeing that current educational quality is adequate. Fifty-six percent of massage educators and 40% of CIHC educators agreed that educational quality needs to improve if massage therapists want to be considered comparable to other allied health professionals. Both groups suggested specific areas and means of improvement, including raising admission requirements and offering an academic degree. Conclusions Accreditation appears to improve the quality of massage education; however, more consistent methods for calculating tuition costs, educational outcomes, and classifying severity of disciplinary actions are needed. Both quantitative and qualitative evidence indicates that the current quality of massage education in the US is inconsistent and less than adequate. Specific areas of improvement needed for massage therapists to be perceived as comparable to other allied healthcare providers are described. PMID:25184011

Hyaluronic acid injections protect patellar tendon from detraining-associated damage.

PubMed

Frizziero, Antonio; Salamanna, Francesca; Giavaresi, Gianluca; Ferrari, Andrea; Martini, Lucia; Marini, Marina; Veicsteinas, Arsenio; Maffulli, Nicola; Masiero, Stefano; Fini, Milena

2015-09-01

Having previously demonstrated that detraining affects patellar tendon (PT) proteoglycan content and collagen fiber organization, we undertook the present study with two aims: to improve knowledge on the adaptation of PT and its enthesis to detraining from a histological and histomorphometric point of view, and to investigate the hypothesis that repeated peri-patellar injections of hyaluronic acid (HA) on detrained PT may reduce and limit detrained associated-damage. Twenty-four male Sprague-Dawley rats were divided into 3 groups: Untrained (n=6), Trained (n=6) (10 wks-treadmill) and Detrained (n=12). In the detrained rats, the left tendon was untreated while the right tendon received repeated peri-patellar injections of either HA or saline (NaCl). Structure and morphology of PTs (modified Movin score, tear density, collagen type I and III) and enthesis (cell morphology, chondrocyte cluster formation, tidemark integrity, matrix staining and vascularization) were evaluated. The left PT and enthesis of the Detrained groups showed altered structure and morphology with the highest Movin score values, the highest percentage of collagen III and the lowest of collagen I; the lowest score values were observed in the Trained and Detrained-HA groups. Detrained-NaCl PTs showed the highest collagen III and the lowest collagen I values with respect to Detrained-HA PTs. This study strengthens previously published data showing the alteration in tendon and enthesis morphology due to discontinuation of training, and provides new data showing that treatment with HA is effective in the maintenance of the structural properties of PT and enthesis in Detrained rats. Such beneficial effects could play a significant role in the management of conservative and rehabilitation strategies in athletes that change type, intensity and duration of training.

Effect of thermal aging on the tensile bond strength at reduced areas of seven current adhesives.

PubMed

Baracco, Bruno; Fuentes, M Victoria; Garrido, Miguel A; González-López, Santiago; Ceballos, Laura

2013-07-01

The purpose of this study was to determine the micro-tensile bond strength (MTBS) to dentin of seven adhesive systems (total and self-etch adhesives) after 24 h and 5,000 thermocycles. Dentin surfaces of human third molars were exposed and bonded with two total-etch adhesives (Adper Scotchbond 1 XT and XP Bond), two two-step self-etch adhesives (Adper Scotchbond SE and Filtek Silorane Adhesive System) and three one-step self-etch adhesives (G-Bond, Xeno V and Bond Force). All adhesive systems were applied following manufacturers' instructions. Composite buildups were constructed and the bonded teeth were then stored in water (24 h, 37 °C) or thermocycled (5,000 cycles) before being sectioned and submitted to MTBS test. Two-way ANOVA and subsequent comparison tests were applied at α = 0.05. Characteristic de-bonded specimens were analyzed using scanning electron microscopy (SEM). After 24 h water storage, MTBS values were highest with XP Bond, Adper Scotchbond 1 XT, Filtek Silorane Adhesive System and Adper Scotchbond SE and lowest with the one-step self-etch adhesives Bond Force, Xeno V and G-Bond. After thermocycling, MTBS values were highest with XP Bond, followed by Filtek Silorane Adhesive System, Adper Scotchbond SE and Adper Scotchbond 1 XT and lowest with the one-step self-etch adhesives Bond Force, Xeno V and G-Bond. Thermal aging induced a significant decrease in MTBS values with all adhesives tested. The resistance of resin-dentin bonds to thermal-aging degradation was material dependent. One-step self-etch adhesives obtained the lowest MTBS results after both aging treatments, and their adhesive capacity was significantly reduced after thermocycling.

Predictive Value of Different Expressions of Forced Expiratory Volume in 1 Second (FEV1) for Adverse Outcomes in a Cohort of Adults Aged 80 and Older.

PubMed

Hegendörfer, Eralda; Vaes, Bert; Andreeva, Elena; Matheï, Catharina; Van Pottelbergh, Gijs; Degryse, Jean-Marie

2017-02-01

Forced expiratory volume in 1 second (FEV 1 ) is proposed as a marker of healthy ageing and FEV 1 expressions that are independent of reference values have been reported to be better at predicting mortality in older adults. We assess and compare the predictive value of different FEV 1 expressions for mortality, hospitalization, and physical and mental decline in adults aged 80 and older. Population-based, prospective, cohort study. The BELFRAIL study, Belgium. A total of 501 community-dwelling adults aged 80 and older (mean age 84.7 years). Baseline FEV 1 expressed as percent predicted (FEV 1 PP) and z-score (FEV 1 Z) using the Global Lung Function Initiative 2012 reference values; over lowest sex-specific percentile (FEV 1 Q), and height squared (FEV 1 /Ht 2 ) and cubed (FEV 1 /Ht 3 ). Mortality data until 5.1 ± 0.2 years from baseline; hospitalization data until 3.0 ± 0.25 years. Activities of daily living, battery of physical performance tests, Mini-Mental State Examination, and 15-item Geriatric Depression Scale at baseline and after 1.7 ± 0.2 years. Individuals in the lowest quartile of FEV 1 expressions had higher adjusted risk than the rest of study population for all-cause mortality (highest hazard ratio 2.05 [95% Confidence Interval 1.50-2.80] for FEV 1 Q and 2.01 [1.47-2.76] for FEV 1 /Ht 3 ), first hospitalization (highest hazard ratio 1.63 [1.21-2.16] for FEV 1 /Ht 2 and 1.61[1.20-2.16] for FEV 1 /Ht 3 ), mental decline (highest odds ratio 2.80 [1.61-4.89] for FEV 1 Q) and physical decline (only FEV 1 /Ht 3 with odds ratio 1.93 [1.13-3.30]). Based on risk classification improvement measures, FEV 1 /Ht 3 and FEV 1 Q performed better than FEV 1 PP. In a cohort of adults aged 80 and older, FEV 1 expressions that are independent of reference values (FEV 1 /Ht 3 and FEV 1 Q) were better at predicting adverse health outcomes than traditional expressions that depend on reference values, and should be used in further research on FEV 1 and aging. Copyright © 2016 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved.

Accuracy evaluation of contour next compared with five blood glucose monitoring systems across a wide range of blood glucose concentrations occurring in a clinical research setting.

PubMed

Klaff, Leslie J; Brazg, Ronald; Hughes, Kristen; Tideman, Ann M; Schachner, Holly C; Stenger, Patricia; Pardo, Scott; Dunne, Nancy; Parkes, Joan Lee

2015-01-01

This study evaluated the accuracy of Contour(®) Next (CN; Bayer HealthCare LLC, Diabetes Care, Whippany, NJ) compared with five blood glucose monitoring systems (BGMSs) across a wide range of clinically occurring blood glucose levels. Subjects (n=146) were ≥ 18 years and had type 1 or type 2 diabetes. Subjects' glucose levels were safely lowered or raised to provide a wide range of glucose values. Capillary blood samples were tested on six BGMSs and a YSI glucose analyzer (YSI Life Sciences, Inc., Yellow Springs, OH) as the reference. Extreme glucose values were achieved by glucose modification of the blood sample. System accuracy was assessed by mean absolute difference (MAD) and mean absolute relative difference (MARD) across several glucose ranges, with <70 mg/dL evaluated by MAD as the primary end point. In the low glucose range (<70 mg/dL), MAD values were as follows: Accu-Chek(®) Aviva Nano (Roche Diagnostics, Indianapolis, IN), 3.34 mg/dL; CN, 2.03 mg/dL; FreeStyle Lite(®) (FSL; Abbott Diabetes Care, Inc., Alameda, CA), 2.77 mg/dL; OneTouch(®) Ultra(®) 2 (LifeScan, Inc., Milpitas, CA), 10.20 mg/dL; OneTouch(®) Verio(®) Pro (LifeScan, Inc.), 4.53 mg/dL; and Truetrack(®) (Nipro Diagnostics, Inc., Fort Lauderdale, FL), 11.08 mg/dL. The lowest MAD in the low glucose range, from CN, was statistically significantly lower than those of the other BGMSs with the exception of the FSL. CN also had a statistically significantly lower MARD than all other BGMSs in the low glucose range. In the overall glucose range (21-496 mg/dL), CN yielded the lowest MAD and MARD values, which were statistically significantly lower in comparison with the other BGMSs. When compared with other BGMSs, CN demonstrated the lowest mean deviation from the reference value (by MAD and MARD) across multiple glucose ranges.

What causes EBRI retirement readiness ratings to vary: results from the 2014 Retirement Security Projection Model.

PubMed

VanDerhei, Jack

2014-02-01

RETIREMENT INCOME ADEQUACY IMPROVED SLIGHTLY IN 2013: Due to the increase in financial market and housing values during 2013, the probability that Baby Boomers and Generation Xers would NOT run short of money in retirement increases between 0.5 and 1.6 percentage points, based on the Employee Benefit Research Institute (EBRI) Retirement Readiness Ratings (RRRs). ELIGIBILITY FOR PARTICIPATION IN AN EMPLOYER-SPONSORED DEFINED CONTRIBUTION PLAN REMAINS ONE OF THE MOST IMPORTANT FACTORS FOR RETIREMENT INCOME ADEQUACY: RRR values double for Gen Xers in the lowest-income quartile when comparing those with 20 or more years of future eligibility with those with no years of future eligibility, while those in the middle income quartiles experience increases in RRR values by 27.1-30.3 percentage points. FUTURE SOCIAL SECURITY BENEFITS MAKE A HUGE DIFFERENCE FOR THE RETIREMENT INCOME ADEQUACY OF SOME HOUSEHOLDS, ESPECIALLY GEN XERS IN THE LOWEST-INCOME QUARTILE: If Social Security benefits are subject to proportionate decreases beginning in 2033 (according to the values in Figure 8), the RRR values for those households will drop by more than 50 percent: from 20.9 percent to 10.3 percent. LONGEVITY RISK AND STOCHASTIC HEALTH CARE RISK ARE ASSOCIATED WITH HUGE VARIATIONS IN RETIREMENT INCOME ADEQUACY: For both of these factors, a comparison between the most "risky" quartile with the least risky quartile shows a spread of approximately 30 percentage points for the lowest income range, approximately 25 to 40 percentage points for the highest income range, and even larger spreads for those in the middle income ranges. A GREAT DEAL OF THE VARIABILITY IN RETIREMENT INCOME ADEQUACY COULD BE MITIGATED BY APPROPRIATE RISK-MANAGEMENT TECHNIQUES AT OR NEAR RETIREMENT AGE: For example, the annuitization of a portion of the defined contribution and IRA balances may substantially increase the probability of not running short of money in retirement. Moreover, a well-functioning market in long-term care insurance would appear to provide an extremely useful technique to help control the volatility from the stochastic, long-term health care risk, especially for those in the middle income quartiles.

Wetting of polymer melts on coated and uncoated steel surfaces

NASA Astrophysics Data System (ADS)

Vera, Julie; Contraires, Elise; Brulez, Anne-Catherine; Larochette, Mathieu; Valette, Stéphane; Benayoun, Stéphane

2017-07-01

A comparative study of the wetting of three different commercial polymer melts on various coated and uncoated steel surfaces is described in this report. The wettability of steel and coatings (three different titanium nitride coatings, TiN, TiNOx, TiNOy, a chromium coating, CrN, and a diamond-like carbon coating, DLC) used for mold in polymer processing is determined at different temperatures between 25 °C and 120 °C. Contact angle measurements of melted polypropylene (PP), Acrylonitrile Butadiene Styrene (ABS) and Polycarbonate (PC) on steel and on the different coatings were performed to investigate the wetting behavior under closer-to-processing conditions. Recommendations for good measurement conditions were proposed. Moreover, the surface free energy of each melt polymer was determined. The works of adhesion between all polymers and all substrates were established. Among all tested polymers, the lowest value of the works of adhesion is calculated for ABS and for PC thereafter, and the highest value is calculated for PP. These results will be particularly important for such applications as determining the extent to which these polymers can contribute to the replication quality in injection molding.

Total arsenic in raw and boiled portions of Norway lobster (Nephrops norvegicus) from the central Adriatic Sea.

PubMed

Visciano, Pierina; Perugini, Monia; Manera, Maurizio; Abete, Maria Cesarina; Tarasco, Renata; Salese, Carmine; Amorena, Michele

2013-12-18

The distribution of total arsenic in different portions of Norway lobster (Nephrops norvegicus L., Crustacea) was studied both in fresh samples and after a boiling process. All individuals (n = 80) were selected of medium standard commercial size (13-15 cm). The highest mean concentrations (26.86 ± 1.57 mg/kg wet weight (ww)) were found in the raw brown meat of the crustacean, probably due to its detoxification role, whereas the lowest mean values (15.97 ± 0.85 mg/kg ww) were in the raw exoskeleton. The raw white meat reported mean values of 16.09 ± 0.61 mg/kg ww. The levels of arsenic contamination detected in the boiled portions showed a significant (p < 0.01) decrease compared to the raw portions, as a consequence of solubilization phenomena. In fact, a large amount of arsenic from raw lobsters was transferred to the corresponding boiling broth. In the most commonly consumed portion, the white meat, only slight losses (7.22%) in total arsenic content were observed compared to the raw portion.

Fast Turn-Off Times Observed in Experimental 4H SiC Thyristors

NASA Technical Reports Server (NTRS)

Niedra, Janis M.

2006-01-01

Room temperature measurements of the turn-off time (t(sub q)) are reported for several packaged, npnp developmental power thyristors based on 4H-type SiC and rated 400 V, 2 A. Turn-off is effected by a 50 V pulse of applied reverse voltage, from a state of a steady 1 A forward current. Plots of t(sub q) against the ramp rate (dV(sub AK)/dt) of reapplied forward voltage are presented for preset values of limiting anode-to-cathode voltage (V(sub AK,max)). The lowest t(sub q) measured was about 180 ns. A rapid rise of these t(sub q) curves was observed for values of V(sub AK,max) that are only about a fifth of the rated voltage, whereas comparative t(sub q) plots for a commercial, fast turn-off, Si-based thyristor at a proportionately reduced V(sub AK,max) showed no such behavior. Hence these SiC thyristors may have problems arising from material defects or surface passivation. The influence the R-C-D gate bypass circuit that was used is briefly discussed.

Revalidation of the Isobaric Multiplet Mass Equation for the A =20 quintet

NASA Astrophysics Data System (ADS)

Glassman, Brent; Perez-Loureiro, D.; Wrede, C.; Allen, J.; Bardyan, D.; Bennett, M.; Brown, A.; Chipps, K.; Febbraro, M.; Fry, Cathleen; Hall, O.; Hall, M.; Liddick, S.; O'Malley, P.; Ong, W.; Pain, S.; Schwartz, S.; Shidling, P.; Sims, H.; Thompson, P.; Zhang, E.

2016-03-01

An unexpected breakdown of the Isobaric Multiplet Mass Equation (IMME) for the A =20, T =2 quintet was recently reported based on a precise measurement of the 20Mg mass and adopted data on the other members. The adopted value for 20Na presented the greatest deviation from the IMME fit and was based on relatively imprecise beta delayed proton decay measurements. We used the superallowed 0+ to 0+ beta decay of 20Mg to feed the lowest T =2 state in 20Na, and the high purity germanium detector array SeGA to detect its gamma-ray de-excitation for the first time. Using the gamma-ray energies, we were able to precisely measure the excitation energy to be 6498.4 +/-0 .2stat+/-0.4syst keV. By incorporating this newly measured value we find that the IMME is revalidated. We gratefully acknowledge the NSCL staff for technical assistance and for providing the 20Mg beam. This work was supported by the National Science Foundation (USA) under Grants No. PHY-1102511, No. PHY-1419765, and No. PHY-1404442.

Nutritional composition of minor indigenous fruits: cheapest nutritional source for the rural people of Bangladesh.

PubMed

Tariqul Islam Shajib, Mohammad; Kawser, Mahbuba; Nuruddin Miah, Mohammad; Begum, Parveen; Bhattacharjee, Lalita; Hossain, A; Fomsgaard, Inge S; Islam, Sheikh Nazrul

2013-10-01

In line of the development of a food composition database for Bangladesh, 10 minor indigenous fruits were analysed for their nutrient composition comprising ascorbic acid, carotenoids and mineral values. Nutrient data obtained have been compared with published data reported in different literatures, book and United States Department of Agriculture-National Nutrient Database for Standard Reference. Ascorbic acid was highest in Wood apple and lowest in Roselle. Monkey jack contained the highest amount of carotenoids, zinc and copper. Content of calcium, magnesium and phosphorous were found highest in Antidesma velutinum. Potassium was the highest in Wood apple followed by in Moneky jack. It was noted that most of the minor fruits have much higher amount of ascorbic acid than the national fruit - Jack fruit ripe, the king fruit - Mango ripe of Bangladesh and exotic fruits - Apple and Grapes. The nutrient values of these minor fruits would make awareness among the people for their mass consumption for healthy life and to grow more minor fruit trees from extinction in order to maintain biodiversity. Copyright © 2012 Elsevier Ltd. All rights reserved.

Use of an electronic medical record for the identification of research subjects with diabetes mellitus.

PubMed

Wilke, Russell A; Berg, Richard L; Peissig, Peggy; Kitchner, Terrie; Sijercic, Bozana; McCarty, Catherine A; McCarty, Daniel J

2007-03-01

Diabetes mellitus is a rapidly increasing and costly public health problem. Large studies are needed to understand the complex gene-environment interactions that lead to diabetes and its complications. The Marshfield Clinic Personalized Medicine Research Project (PMRP) represents one of the largest population-based DNA biobanks in the United States. As part of an effort to begin phenotyping common diseases within the PMRP, we now report on the construction of a diabetes case-finding algorithm using electronic medical record data from adult subjects aged > or =50 years living in one of the target PMRP ZIP codes. Based upon diabetic diagnostic codes alone, we observed a false positive case rate ranging from 3.0% (in subjects with the highest glycosylated hemoglobin values) to 44.4% (in subjects with the lowest glycosylated hemoglobin values). We therefore developed an improved case finding algorithm that utilizes diabetic diagnostic codes in combination with clinical laboratory data and medication history. This algorithm yielded an estimated prevalence of 24.2% for diabetes mellitus in adult subjects aged > or =50 years.

Inorganic particle analysis of dental impression elastomers.

PubMed

Carlo, Hugo Lemes; Fonseca, Rodrigo Borges; Soares, Carlos José; Correr, Américo Bortolazzo; Correr-Sobrinho, Lourenço; Sinhoreti, Mário Alexandre Coelho

2010-01-01

The aim of this study was to determine quantitatively and qualitatively the inorganic particle fraction of commercially available dental elastomers. The inorganic volumetric fraction of two addition silicones (Reprosil Putty/Fluid and Flexitime Easy Putty/Fluid), three condensation silicones (Clonage Putty/Fluid, Optosil Confort/Xantopren VL and Silon APS Putty/Fluid), one polyether (Impregum Soft Light Body) and one polysulfide (Permlastic Light Body) was accessed by weighing a previously determined mass of each material in water before and after burning samples at 600 ºC, during 3 h. Unsettled material samples were soaked in acetone and chloroform for removal of the organic portion. The remaining filler particles were sputter-coated with gold evaluation of their morphology and size, under scanning electron microscopy (SEM). Flexitime Easy Putty was the material with the highest results for volumetric particle fraction, while Impregum Soft had the lowest values. Silon 2 APS Fluid presented the lowest mean filler size values, while Clonage Putty had the highest values. SEM micrographs of the inorganic particles showed several morphologies - lathe-cut, spherical, spherical-like, sticks, and sticks mixed to lathe-cut powder. The results of this study revealed differences in particle characteristics among the elastometic materials that could lead to different results when testing mechanical properties.

Low-dose caffeine discrimination and self-reported mood effects in normal volunteers.

PubMed Central

Silverman, K; Griffiths, R R

1992-01-01

A caffeine versus placebo discrimination procedure was used to determine the lowest caffeine dose that could produce discrimination and self-reported mood effects in normal volunteers. During daily sessions under double-blind conditions, caffeine-abstinent subjects orally ingested a capsule containing 178 mg caffeine or placebo. Before beginning discrimination training, the compounds were identified to subjects by letter codes. Fifteen, 30, and 45 min after capsule ingestion, subjects guessed the capsule's letter code. Correct guesses at 45 min earned money. After each session, subjects received a supplementary capsule containing caffeine or placebo to ensure that, within each phase of the study, subjects received the same daily dose of caffeine equal to the training dose. Five of the 15 subjects acquired the caffeine versus placebo discrimination within the first 20 sessions (greater than or equal to 75% correct); 6 other subjects acquired the discrimination with additional training. Nine subjects who acquired the discrimination were subsequently trained at progressively lower caffeine doses. In general, the lowest dose to produce discrimination (greater than or equal to 75% correct) was also the lowest dose to produce self-reported mood effects: 4 subjects showed discrimination and self-reported mood effects at 100 mg caffeine, 2 at 56 mg, 1 at 32 mg, and 1 at 18 mg. One of these subjects also showed self-reported mood effects at 10 mg. The present study documents discriminative stimulus and self-reported mood effects of caffeine at doses below those previously shown to affect any behavior in normal volunteers. PMID:1548451

Cardiovascular diseases and hard drinking waters: implications from a systematic review with meta-analysis of case-control studies.

PubMed

Gianfredi, Vincenza; Bragazzi, Nicola Luigi; Nucci, Daniele; Villarini, Milena; Moretti, Massimo

2017-02-01

This systematic review with meta-analysis, performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines, aims at evaluating the potential correlation between magnesium and calcium concentration in drinking waters and the risk of cardiovascular diseases (CVD), which impose a considerable burden in high-income countries. Included studies were of the case-control studies type. From an initial list of 643 potentially eligible articles, seven studies were finally retained in the quantitative analysis. Since each one of them assessed different ion concentrations, subjects exposed to the highest concentration versus those exposed to the lowest concentration were compared. By including an overall figure of 44,000 subjects, the result suggests a protective effect of the ions on CVD prevention, with an effect-size (ES) of 0.82 (95% confidence interval CI = [0.70-0.95], p-value = 0.008) for calcium, and ES = 0.75 (95% CI = [0.66-0.86], p-value = 0.000) for magnesium. Hard water consumption seems to be protective against CVD. However, the high heterogeneity (I 2 = 75.24, p-value = 0.001 for calcium; I 2 = 72.96, p-value = 0.0024 for magnesium) and the existence of publication bias limits the robustness and generalizability of these findings. Further high-quality studies are needed to reproduce and confirm these results.

The Evolution of the Shared Services Business Unit.

ERIC Educational Resources Information Center

Forst, Leland

2000-01-01

Explains shared services, where common business practices are applied by a staff unit focused entirely on delivering needed services at the highest value and lowest cost to internal customers. Highlights include accountability; examples of pioneering shared services organizations; customer focus transition; relationship management; expertise…

Conformal versus confining scenario in SU(2) with adjoint fermions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Del Debbio, L.; Pica, C.; Lucini, B.

2009-10-01

The masses of the lowest-lying states in the meson and in the gluonic sector of an SU(2) gauge theory with two Dirac flavors in the adjoint representation are measured on the lattice at a fixed value of the lattice coupling {beta}=4/g{sub 0}{sup 2}=2.25 for values of the bare fermion mass m{sub 0} that span a range between the quenched regime and the massless limit, and for various lattice volumes. Even for light constituent fermions the lightest glueballs are found to be lighter than the lightest mesons. Moreover, the string tension between two static fundamental sources strongly depends on the massmore » of the dynamical fermions and becomes of the order of the inverse squared lattice linear size before the chiral limit is reached. The implications of these findings for the phase of the theory in the massless limit are discussed and a strategy for discriminating between the (near-)conformal and the confining scenario is outlined.« less

Diffusion-weighted MR imaging of the pancreas: optimizing b-value for visualization of pancreatic adenocarcinoma.

PubMed

Fukukura, Yoshihiko; Shindo, Toshikazu; Hakamada, Hiroto; Takumi, Koji; Umanodan, Tomokazu; Nakajo, Masanori; Kamimura, Kiyoshisa; Umanodan, Aya; Ideue, Junnichi; Yoshiura, Takashi

2016-10-01

To determine the optimal b-value of 3.0-T diffusion-weighted imaging (DWI) for visualizing pancreatic adenocarcinomas Fifty-five patients with histologically confirmed pancreatic adenocarcinoma underwent DWI with different b-values (b = 500, 1000, 1500, and 2000 s/mm(2)) at 3.0 T. For each b-value, we retrospectively evaluated DWI findings of pancreatic adenocarcinomas (clear hyperintensity relative to the surrounding pancreas, hyperintensity with an unclear distal border, and isointensity) and image quality, and measured tumour-to-pancreas signal intensity (SI) ratios. DWI findings, image quality, and tumour-to-pancreas SI ratios were compared between the four b-values. There was a significantly higher incidence of tumours showing clear hyperintensity on DWI with b-value of 1500 s/mm(2) than on that with b-value of 1000 s/mm(2) (P < 0.001), and on DWI with b-value of 1000 s/mm(2) than on that with b-value of 500 s/mm(2) (P < 0.001). The tumour-to-distal pancreas SI ratio was higher with b-value of 1500 s/mm(2) than with b-value of 1000 s/mm(2) (P < 0.001), and with b-value of 1000 s/mm(2) than with b-value of 500 s/mm(2) (P < 0.001). A lower image quality was obtained at increasing b-values (P < 0.001); the lowest scores were observed with b-value of 2000 s/mm(2). The use of b = 1500 s/mm(2) for 3.0-T DWI can improve the delineation of pancreatic adenocarcinomas. • Diffusion-weighted imaging (DWI) has been used for diagnosing pancreatic adenocarcinoma • The techniques for DWI, including the choice of b-values, vary considerably • DWI often fails to delineate pancreatic adenocarcinomas because of hyperintense pancreas • DWI with a higher b-value can improve the tumour delineation • The lowest image quality was obtained on DWI with b-value = 2000 s/mm (2).

Effects of Zr, Ti, and Al Additions on Nonmetallic Inclusions and Impact Toughness of Cast Low-Alloy Steel

NASA Astrophysics Data System (ADS)

Bizyukov, Pavel V.; Giese, Scott R.

2017-04-01

A microalloying of the low-carbon and low-alloy cast steel was conducted with Zr, Ti, and Al that were added to the steel in four combinations. After heat treatment, the samples were tested for impact toughness at room temperature using the Charpy method. The highest values of impact toughness were obtained in the group treated with Zr, while Zr-Ti and Zr-Ti-Al groups showed moderate toughness values; the lowest values were observed in the Zr-Al group. Difference among the treatment groups was observed in the fracture mechanisms, morphology, and area distribution of the inclusions. High toughness values achieved in the trials treated with zirconium corresponded with smooth ductile fracture. The metal treated with a combination of zirconium and titanium had a relatively small area occupied by inclusions, but its toughness was also moderate. Lowest impact toughness values corresponded with the larger area occupied by the inclusions in the trials treated with aluminum. Also, a connection between the solubility product [Al][N] and impact toughness was established. The study also provides a qualitative description and quantitative analysis of the nonmetallic inclusions formation as a result of microalloying treatment. The precipitation sequence of the inclusions was described based on the thermochemical calculations for the nonmetallic compounds discovered in the experimental steel. A description of the size distribution, morphology, and composition was conducted for the oxides, nitrides, sulfides, and multiphase particles.

Frictional resistance of self-ligating versus conventional brackets in different bracket-archwire-angle combinations

PubMed Central

MONTEIRO, Maria Regina Guerra; da SILVA, Licinio Esmeraldo; ELIAS, Carlos Nelson; VILELLA, Oswaldo de Vasconcellos

2014-01-01

Objective To compare the influence of archwire material (NiTi, beta-Ti and stainless steel) and brackets design (self-ligating and conventional) on the frictional force resistance. Material and Methods Two types of brackets (self-ligating brackets - Smartclip, 3M/Unitek - and conventional brackets - Gemini, 3M/Unitek) with three (0, 5, and 10 degrees) slot angulation attached with elastomeric ligatures (TP Orthodontics) were tested. All brackets were tested with archwire 0.019"x0.025" nickel-titanium, beta-titanium, and stainless steel (Unitek/3M). The mechanical testing was performed with a universal testing machine eMIC DL 10000 (eMIC Co, Brazil). The wires were pulled from the bracket slots at a cross-head speed of 3 mm/min until 2 mm displacement. Results Self-ligating brackets produced significantly lower friction values compared with those of conventional brackets. Frictional force resistance values were directly proportional to the increase in the bracket/ wire angulation. With regard to conventional brackets, stainless steel wires had the lowest friction force values, followed by nickel-titanium and beta-titanium ones. With regard to self-ligating brackets, the nickel-titanium wires had the lowest friction values, significantly lower than those of other materials. Conclusion even at different angulations, the self-ligating brackets showed significantly lower friction force values than the conventional brackets. Combined with nickel-titanium wires, the self-ligating brackets exhibit much lower friction, possibly due to the contact between nickel-titanium clips and wires of the same material. PMID:25025564

Thymic function, anti-thymocytes globulins, and cancer after renal transplantation.

PubMed

Ducloux, Didier; Bamoulid, Jamal; Courivaud, Cécile; Gaugler, Béatrice; Rebibou, Jean-Michel; Ferrand, Christophe; Chalopin, Jean-Marc; Borg, Christophe; Tiberghien, Pierre; Saas, Philippe

2011-07-01

Prolonged CD4 T cell lymphopenia after polyclonal antithymocyte globulins (ATG) is associated with an increased rate of cancers. Here, we examined whether pre-transplant thymic function estimated by TREC levels is predictive of cancer occurrence following ATG treatment. The impact of TREC on cancer occurrence was analyzed in 115 consecutive incident renal transplant recipients having received ATG. Mean follow-up was 7.5±2.6years. After ATG induction, patients with the lowest pre-transplant TREC values had lower post-transplant CD4(+) and CD4(+) CD45RA(+) CD45RO(-) T cell counts, and a higher frequency of T cells with a regulatory phenotype (CD127(+)CD4(+)CD25(+)Foxp3(+)). Log-transformed pre-transplant TREC values were significantly lower in patients who developed cancer after transplantation (p<0.0001). The cumulative incidence of cancer was higher in patients having the lowest pre-transplant TREC values (T1 [low]: 47.4%, T2 [medium]: 12.5%, and T3 [high]: 2.7%; p<0.0001). In multivariate analysis, pre-transplant TREC value was the only predictive factor of cancer (HR, 0.39; 95% CI, 0.16 to 0.97, for one log (TREC/10(6) PBMC); p=0.046). Pre-transplant thymic function is associated with an increased rate of post-transplant cancer in patients having received ATG. Omitting ATG in recipients with low pre-transplant TREC values should be considered. Copyright © 2011 Elsevier B.V. All rights reserved.

Systematic evaluation of tumoral 99mTc-MAA uptake using SPECT and SPECT/CT in 502 patients before 90Y radioembolization.

PubMed

Ilhan, Harun; Goritschan, Anna; Paprottka, Phillip; Jakobs, Tobias F; Fendler, Wolfgang P; Bartenstein, Peter; Hacker, Marcus; Haug, Alexander R

2015-03-01

The aim of this study was to evaluate the (99m)Tc-macroaggregated albumin ((99m)Tc-MAA) uptake of primary and secondary liver tumors in a large patient cohort before (90)Y radioembolization. We included 502 patients during the years 2005-2013 (55% male; mean age, 62 ± 11 y), who were examined with (99m)Tc-MAA SPECT or SPECT/CT before planned radioembolization. The patients had colorectal cancer (CRC; n = 195, 38.8%), neuroendocrine tumors (NET; n = 77, 15.3%), mammary cancer (MAM; n = 68, 13.5%), hepatocellular carcinoma (HCC; n = 59, 11.8%), cholangiocellular carcinoma (CCC; n = 40, 8.0%), or urologic tumors (URO; n = 14, 2.8%). SPECT with coregistered contrast-enhanced CT or MR imaging and SPECT/CT images of these patients were analyzed using dedicated software with regard to the (99m)Tc-MAA uptake of the liver tumors. Regions of interest were drawn around the lesions manually and quantified the uptake of up to 3 lesions per patient and also adjacent healthy liver tissue without evidence of tumor. We quantified maximum and mean counts per pixel and calculated tumor-to-background ratio (TBR). Data are reported as mean ± SD. Lesion uptake was classified as being homogeneously high (grade 1), heterogeneously high (grade 2), equal to that of the liver (grade 3), or low (grade 4). Grade 1 uptake was seen in 230 of 1,008 lesions (with the highest rates in sarcoma [47%], MAM [37%], and NET [32%]), grade 2 in 706 lesions (with the highest rates in CRC [77%], HCC [75%], and CCC [74%]), grade 4 in 57 lesions (with the highest rates in pancreatic cancer [17%], sarcoma [SAR] [13%], and MAM [8%]), and grade 3 in only 15 lesions. In quantitative analysis, the mean TBRmax of all lesions was 4.8 ± 4.1 (range, 0.2-50.1), with the highest values in HCC (6.0 ± 4.7; range, 1.4-21.6), NET (5.4 ± 4.9; range, 0.8-43.0), pancreatic cancer (4.0 ± 2.8; range, 0.9-12.2), and CCC (4.7 ± 2.9; range, 0.9-11.6), and the lowest values in SAR (3.5 ± 1.8; range, 0.8-2.7) and MAM (3.6 ± 2.2; range, 0.9-11.6). The mean TBRmean was 1.9 ± 1.0 (range, 0.1-7.2), with the highest values in NET (2.2 ± 1.2; range, 0.2-7.2), HCC (2.1 ± 1.2; range, 0.3-6.3), and CCC (2.0 ± 1.0; range, 0.2-6.3) and the lowest values in MAM (1.7 ± 0.8; range, 0.2-4.1), CRC (1.8 ± 0.9; range, 0.4-6.6), and SAR (1.7 ± 1.1; range, 0.3-3.9). The (99m)Tc-MAA uptake of different tumor entities shows a wide variation, with generally highest values for NET, HCC, and CCC and lowest values for MAM, CRC, and SAR. However, the variation of uptake within the different tumor entities is high. © 2015 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Fatigability and functional performance among older adults with low-normal ankle-brachial index: Cross-sectional findings from the Baltimore Longitudinal Study of Aging.

PubMed

Martinez-Amezcua, Pablo; Matsushita, Kunihiro; Simonsick, Eleanor M; Ferrucci, Luigi; Schrack, Jennifer A

2018-05-01

Peripheral artery disease (PAD) is associated with poor mobility and fatigue, but the relationship between preclinical ankle-brachial index (ABI) and early markers of fatigue and functional decline has not been defined. 570 adults, 50 and older, from the Baltimore Longitudinal Study of Aging (N = 570), with normal values of ABI (1-1.39), were classified into ABI tertiles. Perceived fatigability was assessed after a 5-min, treadmill walk (1.5 mph) using the Borg rating of perceived exertion (RPE, range 6-20). Functional evaluation included the Health, Aging and Body Composition Physical Performance Battery (HABC PPB), time to complete a 400-m corridor walk (LDCW), and VO 2 peak (ml/kg/min). High RPE and poor walking endurance (PWE) were defined as RPE≥10 and taking >5 min for the LDCW, respectively. Differences between tertiles in fatigability and functional measures were tested adjusting for demographics, behavioral characteristics, self-reported fatigue, and medical history. Mean LDCW time and RPE were greater for participants in the lowest tertile compared to those in the highest; mean VO 2 peak and HABC PPB scores were lower, suggesting hierarchical associations between fatigability, functional performance, and ABI (p < 0.05 for all). Odds of PWE were greater for those in the lowest ABI tertile compared to the highest; odds of reporting high RPE were greater for those in the middle tertile. Lower ABI is associated with poorer physical function and increased fatigability, suggesting that early changes in ABI may infer greater risk of functional decline, even among those who may not progress to PAD. Copyright © 2018 Elsevier B.V. All rights reserved.

[Frequency of childhood asthma in various Italian regions. Results from ISAAC. Collaborating group of ISRDCE (Italian Studies of Respiration Disorders in Childhood and the Environment)].

PubMed

1997-01-01

In the framework of ISAAC-International Studies on Asthma and Allergies in Childhood--the SIDRIA collaborative project--Studi Italiani sui Disturbi Respiratori nell'Infanzia e l'Ambiente--was established in order to estimate the prevalence of asthma, rinithis and eczema in ten geographic areas in Italy. Data collection spanned from October 1994 to March 1995. Overall 18,737 children 6-7 years old in the primary schools and 21,846 adolescents 13-14 years old in the secondary schools entered the study. The parents of pupils in both age groups filled in standardised questionnaires at home; furthermore both a traditional and a video questionnaire was administered at school to the adolescents. The overall response rate was 96.3%. Based on the interviews to the parents a prevalence of asthma of 9.0% in both age groups was estimated, with the lowest values in Cremona (4.6% children; 6.2% adolescents) and the highest in Roma (11.1% children; 10.4% adolescents). Parents also reported a higher prevalence of wheezing (7.7%) and dyspnea (5.3%) in the last year among children than among adolescents (4.7% and 3.4% respectively). Through the direct interview of the adolescents higher prevalence of asthma (10.4%), wheezing (10.3%) and dyspnea (7.8%) were estimated. Within a narrow range of variability, the reported prevalence of asthma and asthmatic symptoms in Trento and Cremona were the lowest and those in Roma, Empoli and Siena the highest. Nor an urban-rural neither a north-south gradient was detected. A higher prevalence of the same disorders was observed among females than males in the youngest age group, but this difference was no more evident among the adolescents.

Control of multiwall carbon nanotubes dispersion in polyamide6 matrix: An assessment through electrical conductivity

NASA Astrophysics Data System (ADS)

Kodgire, Pravin V.; Bhattacharyya, Arup R.; Bose, Suryasarathi; Gupta, Nitin; Kulkarni, Ajit R.; Misra, Ashok

2006-12-01

The homogeneous dispersion of carbon nanotubes (CNT) remains a hindrance in exploiting the exceptional properties associated with CNT in polymer/CNT composites. Here we present for the first time the key role of sodium salt of 6-aminohexanoic acid (Na-AHA) in assisting debundling the multiwall carbon nanotubes (MWNT) through specific interactions leading to homogeneous dispersion within polyamide6 (PA6) matrix during melt-mixing. The composite fabricated via this route exhibits low electrical percolation threshold of 0.5 wt% at room temperature, the lowest reported value in this system so far. FTIR and Raman spectroscopy reveal the existence of 'cation-π' interaction between Na-AHA and MWNT. The phenomenon of reactive coupling between amine functionality of Na-AHA and acid end group of PA6 during melt-mixing is also established.

Masking properties of ceramics for veneer restorations.

PubMed

Skyllouriotis, Andreas L; Yamamoto, Hideo L; Nathanson, Dan

2017-10-01

The translucency and opacity of ceramics play a significant role in emulating the natural color of teeth, but studies of the masking properties and limitations of dental ceramics when used as monolayer restorations are lacking. The purpose of this in vitro study was to determine the translucency of 6 materials used for veneer restorations by assessing their translucency parameters (TPs), contrast ratios (CRs), and potential to mask dark tooth colors. Ten square- or disk-shaped specimens (0.5-mm thickness, shade A2) were fabricated from Vitablocks Mark II (VMII; Vita Zahnfabrik), IPS e.max CAD LT (EMXC LT; Ivoclar Vivadent AG), IPS e.max CAD HT (EMXC HT; Ivoclar Vivadent AG), IPS Empress CAD LT (EMP LT; Ivoclar Vivadent AG), IPS e.max Press LT (EMXP LT; Ivoclar Vivadent AG), and CZR (CZR; Kuraray Noritake Dental Inc). Their luminance (Y) values over black and over white tiles were measured, followed by their color (CIELab) over black tiles and white tiles and shaded A2 (control group), A3.5, A4, and B4 acrylic resin blocks. All measurements were performed using a spectrophotometer in 2 different areas on each specimen. Then CRs, TPs, and color differences (over shaded backgrounds) were determined. Data were subjected to 1-way and 2-way ANOVA (α=.05) for analysis. Mean CR values of EMXP LT were significantly higher than those of the other tested materials, whereas VMII and EMXC HT had the lowest values (P<.001). Mean TP values over black and over white backgrounds of VMII and EMXC HT were significantly higher than those of the other tested materials, while EMXP LT and EMXC LT revealed the lowest values (P<.001). Background shade A4 displayed the highest mean effect (expressed in ΔE* values) on the color of the ceramic materials, whereas shade B4 demonstrated the lowest mean background effect (P<.001). Significant differences in translucency among the tested ceramics were revealed (P<.001). The EMXC LT and EMXP LT groups were the least translucent under the conditions of this study (P<.001). All tested ceramics exhibited poor masking properties against the A4 background. The color differences of most tested ceramics were more acceptable when tested against the B4 background (ΔE*≤3.3). Copyright © 2016 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

Determination and validation of an aquatic Maximum Acceptable Concentration-Environmental Quality Standard (MAC-EQS) value for the agricultural fungicide azoxystrobin.

PubMed

Rodrigues, Elsa Teresa; Pardal, Miguel Ângelo; Gante, Cristiano; Loureiro, João; Lopes, Isabel

2017-02-01

The main goal of the present study was to determine and validate an aquatic Maximum Acceptable Concentration-Environmental Quality Standard (MAC-EQS) value for the agricultural fungicide azoxystrobin (AZX). Assessment factors were applied to short-term toxicity data using the lowest EC 50 and after the Species Sensitivity Distribution (SSD) method. Both ways of EQS generation were applied to a freshwater toxicity dataset for AZX based on available data, and to marine toxicity datasets for AZX and Ortiva ® (a commercial formulation of AZX) obtained by the present study. A high interspecific variability in AZX sensitivity was observed in all datasets, being the copepoda Eudiaptomus graciloides (LC 50,48h  = 38 μg L -1 ) and the gastropod Gibbula umbilicalis (LC 50,96h  = 13 μg L -1 ) the most sensitive freshwater and marine species, respectively. MAC-EQS values derived using the lowest EC 50 (≤0.38 μg L -1 ) were more protective than those derived using the SSD method (≤3.2 μg L -1 ). After comparing the MAC-EQS values estimated in the present study to the smallest AA-EQS available, which protect against the occurrence of prolonged exposure of AZX, the MAC-EQS values derived using the lowest EC 50 were considered overprotective and a MAC-EQS of 1.8 μg L -1 was validated and recommended for AZX for the water column. This value was derived from marine toxicity data, which highlights the importance of testing marine organisms. Moreover, Ortiva affects the most sensitive marine species to a greater extent than AZX, and marine species are more sensitive than freshwater species to AZX. A risk characterization ratio higher than one allowed to conclude that AZX might pose a high risk to the aquatic environment. Also, in a wider conclusion, before new pesticides are approved, we suggest to improve the Tier 1 prospective Ecological Risk Assessment by increasing the number of short-term data, and apply the SSD approach, in order to ensure the safety of aquatic organisms. Copyright © 2016 Elsevier Ltd. All rights reserved.

Direct observation of methyl rotor and vib-rotor states of S0 toluene: a revised torsional barrier due to torsion-vibration coupling.

PubMed

Gascooke, Jason R; Virgo, Edwina A; Lawrance, Warren D

2015-01-14

We report a two dimensional, laser induced fluorescence study of the lowest 345 cm(-1) region of S0 toluene. Methyl rotor levels of 00 up to m = 6 and of 201 up to m = 4 are observed. The rotor levels of 00 and 201 have quite different energy spacings that are well fit by a model that includes strong torsion-vibration coupling between them. The model requires that the rotor barrier height be revised from -4.84 cm(-1) (methyl hydrogens in a staggered conformation) to +1.57 cm(-1) (eclipsed conformation). However, the 3a2″ state lies below the 3a1″ state as expected for a staggered conformation due to energy shifts associated with the torsion-vibration coupling. It is shown that the rotor wave-functions exhibit little localization at the torsional energy minima. The variation in the m = 0 wavefunction probability distribution with torsional angle is shown to be very similar for the previously accepted negative V6 value and the torsion-vibration coupling model as this coupling shifts the phase of the wavefunction by 30° compared with its phase for V6 alone. The presence of a strong Δυ = ± 1 torsion-vibration coupling involving the lowest frequency vibrational mode provides a potential pathway for rapid intramolecular vibrational energy redistribution at higher energies.

Fluid intake of Latin American children and adolescents: results of four 2016 LIQ.IN 7 National Cross-Sectional Surveys.

PubMed

Gandy, J; Martinez, H; Carmuega, E; Arredondo, J L; Pimentel, C; Moreno, L A; Kavouras, S A; Salas-Salvadó, J

2018-06-01

The primary aim of this survey was to report total fluid intake (TFI) and different fluid types for children (4-9 years) and adolescents (10-17 years) in Mexico, Brazil, Argentina and Uruguay. The second aim was to compare TFI with the adequate intake (AI) of water from fluids as recommended by the USA Institute of Medicine. Data were collected using a validated liquid intake 7-day record (Liq.In 7 ). Participants' characteristics, including age, sex and anthropometric measurements were recorded. A total of 733 children and 933 adolescents were recruited. Over 75% of children in Uruguay met the IOM's recommended intake. Fewer children in Argentina (64-72%) and Brazil (41-50%) obtained AI and the lowest values were recorded in Mexico (33-44%), where 16% of boys and 14% girls drank 50% or less of the AI. More adolescents in Argentina (42%) met the AIs than other countries; the lowest was in Mexico (28%). Children and adolescents in Mexico and Argentina drank more sugar sweetened beverages than water. Large numbers of children and adolescents did not meet AI recommendations for TFI, raising concerns about their hydration status and potential effects on mental and physical well-being. Given the negative effects on children's health, the levels of SSB consumption are worrying.

Injectable self-healing carboxymethyl chitosan-zinc supramolecular hydrogels and their antibacterial activity.

PubMed

Wahid, Fazli; Zhou, Ya-Ning; Wang, Hai-Song; Wan, Tong; Zhong, Cheng; Chu, Li-Qiang

2018-04-07

Injectable and self-healing hydrogels have found numerous applications in drug delivery, tissue engineering and 3D cell culture. Herein, we report an injectable self-healing carboxymethyl chitosan (CMCh) supramolecular hydrogels cross-linked by zinc ions (Zn 2+ ). Supramolecular hydrogels were obtained by simple addition of metal ions solution to CMCh solution at an appropriate pH value. The mechanical properties of these hydrogels were adjustable by the concentration of Zn 2+ . For example, the hydrogel with the highest concentration of Zn 2+ (CMCh-Zn4) showed strongest mechanical properties (storage modulus~11,000Pa) while hydrogel with the lowest concentration of Zn 2+ (CMCh-Zn1) showed weakest mechanical properties (storage modulus~220Pa). As observed visually and confirmed rheologically, the CMCh-Zn1 hydrogel with the lowest Zn 2+ concentration showed thixotropic property. CMCh-Zn1 hydrogel also presented injectable property. Moreover, the antibacterial properties of the prepared supramolecular hydrogels were studied against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) by agar well diffusion method. The results revealed Zn 2+ dependent antibacterial properties against both kinds of strains. The inhibition zones were ranging from ~11-24mm and ~10-22mm against S. aureus and E. coli, respectively. We believe that the prepared supramolecular hydrogels could be used as a potential candidate in biomedical fields. Copyright © 2018 Elsevier B.V. All rights reserved.

Intra-abdominal temperature distribution during consolidation hyperthermic intraperitoneal chemotherapy with carboplatin in the treatment of advanced stage ovarian carcinoma.

PubMed

Rettenmaier, Mark A; Mendivil, Alberto A; Gray, Crystal M; Chapman, Amber P; Stone, Michelle K; Tinnerman, Erin J; Goldstein, Bram H

2015-06-01

Hyperthermic intraperitoneal chemotherapy (HIPEC) involves the continuous heating and circulation of chemotherapy throughout the abdominal cavity in an attempt to enhance cytotoxicity. Despite the potential of this chemotherapy procedure, there are scant anatomical temperature distribution studies reporting on this therapeutic process. We prospectively evaluated the temperature of select anatomical (e.g. upper abdominal, mid-abdominal and supra-pubic) sites in 11 advanced stage ovarian cancer patients who were treated with consolidation HIPEC carboplatin (AUC 10). The temperature of the aforementioned anatomical regions and the inflow/outflow tubing was measured at baseline and at 15-min intervals until the procedure's completion. The lowest observed mean composite temperature was 41.1 °C at the supra-pubic site whereas the highest temperature was 42.6 °C, in association with the inflow/outflow tubing. During the various time intervals we also ascertained that the lowest composite temperature was 40.9 °C at baseline (i.e. time 0), whereas the highest value (41.8 °C) occurred at multiple time periods (e.g., 15, 45 and 60 min). The HIPEC temperature variation amongst the various abdominal sites and time intervals was minimal. We also discerned that uniform temperature distribution throughout the abdominal cavity was facilitated when the abdomen was both maximally distended with fluid and a high flow rate was maintained.

An ab initio study on the four electronically lowest-lying states of CH 2 using the state-averaged complete active space second-order configuration interaction method

NASA Astrophysics Data System (ADS)

Yamaguchi, Yukio; Schaefer, Henry F., III

1997-12-01

Four electronically lowest-lying ( X˜ 3B 1, ã 1A 1, b˜ 1B 1, and c˜ 1A 1) states of CH 2 have been investigated systematically using ab initio electronic structure theory. Complete active space (CAS) self-consistent-field (SCF) second-order configuration interaction (SOCI) and state-averaged (SA) CASSCF-SOCI levels of theory have been employed. The CASSCF reference wave function was constructed by minimizing the total energy of a specified state, while the SACASSCF reference wave function was obtained by minimizing the equally weighted total energy of the four ( X˜ 3B 1, ã 1A 1, b˜ 1B 1, and c˜ 1A 1) states. The third excited state ( c˜ 1A 1 or 2 1A 1) is of particular theoretical interest because it is represented by the second root of CASSCF and SOCI Hamiltonian matrices. Theoretical treatments of states not the lowest of their symmetry require special attention due to their tendency of variational collapse to the lower-lying state(s). For these four lowest-lying states total energies and physical properties including dipole moments, harmonic vibrational frequencies, and associated infrared (IR) intensities were determined and compared with the results from the configuration interaction with single and double excitations (CISD) method and available experimental values. The CASSCF-SOCI method should provide the most reliable energetics and physical properties in the present study owing to its fully variational nature in the molecular orbital (MO) and CI spaces for a given state. It is demonstrated that the SACASSCF-SOCI wave functions produce results which are quite consistent with those from the CASSCF-SOCI method. Thus significantly increased application of the SACASSCF-SOCI method to the excited states of a wide variety of molecular systems is expected.

Earthquake hazard analysis for the different regions in and around Ağrı

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bayrak, Erdem, E-mail: erdmbyrk@gmail.com; Yilmaz, Şeyda, E-mail: seydayilmaz@ktu.edu.tr; Bayrak, Yusuf, E-mail: bayrak@ktu.edu.tr

We investigated earthquake hazard parameters for Eastern part of Turkey by determining the a and b parameters in a Gutenberg–Richter magnitude–frequency relationship. For this purpose, study area is divided into seven different source zones based on their tectonic and seismotectonic regimes. The database used in this work was taken from different sources and catalogues such as TURKNET, International Seismological Centre (ISC), Incorporated Research Institutions for Seismology (IRIS) and The Scientific and Technological Research Council of Turkey (TUBITAK) for instrumental period. We calculated the a value, b value, which is the slope of the frequency–magnitude Gutenberg–Richter relationship, from the maximum likelihoodmore » method (ML). Also, we estimated the mean return periods, the most probable maximum magnitude in the time period of t-years and the probability for an earthquake occurrence for an earthquake magnitude ≥ M during a time span of t-years. We used Zmap software to calculate these parameters. The lowest b value was calculated in Region 1 covered Cobandede Fault Zone. We obtain the highest a value in Region 2 covered Kagizman Fault Zone. This conclusion is strongly supported from the probability value, which shows the largest value (87%) for an earthquake with magnitude greater than or equal to 6.0. The mean return period for such a magnitude is the lowest in this region (49-years). The most probable magnitude in the next 100 years was calculated and we determined the highest value around Cobandede Fault Zone. According to these parameters, Region 1 covered the Cobandede Fault Zone and is the most dangerous area around the Eastern part of Turkey.« less

Estimating added sugars in US consumer packaged goods: An application to beverages in 2007-08.

PubMed

Ng, Shu Wen; Bricker, Gregory; Li, Kuo-Ping; Yoon, Emily Ford; Kang, Jiyoung; Westrich, Brian

2015-11-01

This study developed a method to estimate added sugar content in consumer packaged goods (CPG) that can keep pace with the dynamic food system. A team including registered dietitians, a food scientist and programmers developed a batch-mode ingredient matching and linear programming (LP) approach to estimate the amount of each ingredient needed in a given product to produce a nutrient profile similar to that reported on its nutrition facts label (NFL). Added sugar content was estimated for 7021 products available in 2007-08 that contain sugar from ten beverage categories. Of these, flavored waters had the lowest added sugar amounts (4.3g/100g), while sweetened dairy and dairy alternative beverages had the smallest percentage of added sugars (65.6% of Total Sugars; 33.8% of Calories). Estimation validity was determined by comparing LP estimated values to NFL values, as well as in a small validation study. LP estimates appeared reasonable compared to NFL values for calories, carbohydrates and total sugars, and performed well in the validation test; however, further work is needed to obtain more definitive conclusions on the accuracy of added sugar estimates in CPGs. As nutrition labeling regulations evolve, this approach can be adapted to test for potential product-specific, category-level, and population-level implications.

Analysis of biological factors for determination of air pollution tolerance index of selected plants in Yamuna Nagar, India.

PubMed

Sharma, Manju; Panwar, Neeraj; Arora, Pooja; Luhach, Jyoti; Chaudhry, Smita

2013-05-01

Air pollution tolerance index (APTI) calculated for various plant species growing in vicinity of three different industrial areas (Paper mill, Sugar mill, Thermal Power Plant) and Yamuna River belt of Yamuna Nagar. Studies were carried out to determine the physiological response of ten plant species. The leaf samples collected from these plant species were used to determine their plant APTI by calculating the ascorbic acid, total chlorophyll, pH, and relative water content for all selected sites. Highest pH, relative water content, ascorbic acid and total chlorophyll was observed in Castor (9.86), Parthenium (96.99%), Ficus benghalensis (14.90 mg g(-1)) and Amaranthus (7.08 mg g(-1)) at Yamuna river, Thermal power plant, Yamuna river and paper mill respectively. It was concluded that out of ten species studied only one species (Ficus benghalensis) showed moderately tolerant response in all selected sites, while other species showed sensitive response. According to observed APTI values, Ficus benghalensis showed the highest value (21.65) at sugar mill followed by thermal power plant (19.38), Paper mill (17.65) and Yamuna River (17.61). The lowest APTI values were reported in Oxalis corniculata (6.42) at Yamuna River belt followed by Malvestrum at sugar mill (7.71).

Estimating added sugars in US consumer packaged goods: An application to beverages in 2007–08

PubMed Central

Ng, Shu Wen; Bricker, Gregory; Li, Kuo-ping; Yoon, Emily Ford; Kang, Jiyoung; Westrich, Brian

2015-01-01

This study developed a method to estimate added sugar content in consumer packaged goods (CPG) that can keep pace with the dynamic food system. A team including registered dietitians, a food scientist and programmers developed a batch-mode ingredient matching and linear programming (LP) approach to estimate the amount of each ingredient needed in a given product to produce a nutrient profile similar to that reported on its nutrition facts label (NFL). Added sugar content was estimated for 7021 products available in 2007–08 that contain sugar from ten beverage categories. Of these, flavored waters had the lowest added sugar amounts (4.3g/100g), while sweetened dairy and dairy alternative beverages had the smallest percentage of added sugars (65.6% of Total Sugars; 33.8% of Calories). Estimation validity was determined by comparing LP estimated values to NFL values, as well as in a small validation study. LP estimates appeared reasonable compared to NFL values for calories, carbohydrates and total sugars, and performed well in the validation test; however, further work is needed to obtain more definitive conclusions on the accuracy of added sugar estimates in CPGs. As nutrition labeling regulations evolve, this approach can be adapted to test for potential product-specific, category-level, and population-level implications. PMID:26273127

Effect of charge on the conformation of highly basic peptides including the tail regions of histone proteins by ion mobility mass spectrometry.

PubMed

Akashi, Satoko; Downard, Kevin M

2016-09-01

The first systematic and comprehensive study of the charging behaviour and effect of charge on the conformation of specifically constructed arginine-rich peptides and its significance to the N- and C-terminal basic tail regions of histone proteins was conducted using ion mobility mass spectrometry (IM-MS). Among the basic amino acids, arginine has the greatest impact on the charging behaviour and structures of gas phase ions by virtue of its high proton affinity. A close linear correlation was found between either the maximum charge, or most abundant charge state, that the peptides support and their average collision cross section (CCS) values measured by ion mobility mass spectrometry. The calculated collision cross sections for the lowest energy solution state models predicted by the PEP-FOLD algorithm using a modified MOBCAL trajectory method were found to best correlate with the values measured by IM-MS. In the case of the histone peptides, more compact folded structures, supporting less than the maximum number of charges, were observed. These results are consistent with those previously reported for histone dimers where neutralization of the charge at the basic residues of the tail regions did not affect their CCS values.

Economic value of big game hunting in southeast Alaska

Treesearch

Cindy Swanson; Michael Thomas; Dennis M. Donnelly

1989-01-01

Surveys in southeast Alaska in 1984 and 1985 were the basis for estimating net willingness to pay of hunters. Net willingness to pay was highest for resident deer hunters ($331) and lowest for nonresident moose hunters ($55). Relationship between willingness to pay and expenditures is discussed.

Value-added service in health care institutions.

PubMed

Umiker, W

1996-12-01

In today's highly competitive atmosphere, the survival of health care institutions depends largely on the ability to provide value-added services (VAS) at the lowest possible cost. Managers must identify their customers and delineate the needs and expectation of those customers. A strategy for satisfying these needs and expectations is essential. While technical advances and reasonable charges are important, a successful "high-tech," "high touch" approach demands the combination of process reengineering and employee training in customer relations.

Olfactory Threshold of Chlorine in Oxygen.

DTIC Science & Technology

1977-09-01

The odor threshold of chlorine in oxygen was determined. Measurements were conducted in an altitude chamber, which provided an odor-free and noise...free background. Human male volunteers, with no previous olfactory acuity testing experience, served as panelists. Threshold values were affected by...time intervals between trials and by age differences. The mean threshold value for 11 subjects was 0.08 ppm obtained by positive responses to the lowest detectable level of chlorine in oxygen, 50% of the time. (Author)

Behavior of total tropospheric ozone, nitrogen oxide and carbon monoxide column over western Indian region by exploring space based satellite observations

NASA Astrophysics Data System (ADS)

Vyas, B. M.; Saxena, Abhishek; Shekhawat, M. S.

2018-05-01

Monthly, seasonal and annual variation of major atmospheric pollutant levels, such as Total Tropospheric Ozone (TO), Total NO2 columnar content (TNO2) and Total CO columnar content (TCO) have been presented first time for eleven district sites of Rajasthan state located in the western tropical Indian region. The study is based on collection of above air pollutant data retrieved from space based satellite measurements by exploring OMI and MOPITT data for a three year period from Jan 2009 to December 2012. A clear, distinct seasonal dependence in TO, TCO and TNO2 column content values have been noticed all over selected measuring location. The maximum average seasonal TO is observed in pre-monsoon and their minimum value in the monsoon months. However, in TCO and TNO2 case, the highest TCO and TNO2 level is seen rather in the winter and their respective lowest value in monsoon season. Thus, their seasonal variability of TNO2 and TCO in their ranges have been systematically found to be reduced and obeyed the following descending order, i.e., winter> post-monsoon> pre-monsoon> monsoon seasons. As far as concerned with their annual values, the observed values of all considered atmospheric pollutants are almost found in the same levels with slight discrepancies over their lower air pollutant levels recorded in hot, arid, rural as compared to the prevailing elevated value at urban region. The more detail investigation of comparison of present observations with earlier reported similar studies over other Indian regions and their possible explanation is also discussed.

[Differences on the contribution of specific components of the metabolic syndrome between hypertensive Latin American and Spanish patients].

PubMed

de la Sierra, Alejandro; Piskorz, Daniel; Plavnik, Frida; Saavedra, Leonardo

2009-06-13

The aim of the present study was to evaluate possible differences in the impact of the components of metabolic syndrome (MS) on hypertensive patients from countries in Latin America and Spain. Cross-sectional study in 632 hypertensives with MS recruited in Argentina, Brazil, Spain, Mexico, Chile, Venezuela and Colombia. Demographic and clinical data, as well as the impact of every single component of the MS were evaluated and compared depending on the country they came from. Mean age was 55(14) years, with 54% females. Thirty-eight percent presented 3 MS criteria, 40% presented 4 criteria, and 22% all the 5 criteria. There were no differences among countries in relation to triglyceride mean values. Subjects from Brazil, Mexico, and Spain showed the highest values of fasting plasma glucose. Women from Venezuela and Brazil showed the highest values of waist circumference and women from Venezuela and Chile the lowest values of HDL-cholesterol. With respect to the proportion of patients with each component alteration, those from Venezuela showed the highest proportion of hypertriglyceridemia (83%) and low HDL-cholesterol (77%), whereas those from Spain exhibited the lowest (56% and 40%). The impact of the components of MS is relatively homogeneous in Latin-America and Spain. However, some differences are detected, with atherogenic dyslipidemia being the predominant factor in Venezuela and abnormal fasting plasma glucose the main one in Spain.

Nutrient composition, mineral content and the solubility of the proteins of palm weevil, Rhynchophorus phoenicis f. (Coleoptera: Curculionidae)

PubMed Central

Omotoso, O.T.; Adedire, C.O.

2007-01-01

Adult (ADS) and larva stages of palm weevil Rhynchophorus phoenicis were analyzed for their nutritional potentials using proximate and mineral contents as indices. The early larva stage (ELS) contains the highest moisture content of 11.94% while ADS has the least value of 4.79%. The late larva stage (LLS) has the highest protein content of 10.51% while ADS contains 8.43%. Ash content is highest in ELS with a value of 2.37% and lowest in ADS with a value of 1.43%. ELS and LLS have the highest (22.14%) and lowest (17.22%) fibre contents respectively. The values of potassium, magnesium and iron in ELS were (455.00±21.21), (60.69±2.57) and (6.50±3.40) mg/kg while LLS recorded (457.50±10.61), (43.52±1.37) and (6.00±1.10) mg/kg and ADS recorded (372.50±24.75), (53.31±1.88) and (22.90±3.70) mg/kg. Chromium, phosphorus, nickel, calcium, lead, manganese and zinc were also detected. Copper was not detected in any of the samples. In all the developmental stages the protein solubilities were pH dependent with the minimum protein solubilities occurring at acidic pH while the maximum protein solubilities occurred at alkaline pH. PMID:17542059

Arsenate (As V) in water: quantitative sensitivity relationships among biomarker, ecotoxicity and genotoxicity endpoints.

PubMed

Silva, Valéria C; Almeida, Sônia M; Resgalla, Charrid; Masfaraud, Jean-François; Cotelle, Sylvie; Radetski, Claudemir M

2013-06-01

It is useful to test ecotoxicity and genotoxicity endpoints in the environmental impact assessment. Here, we compare and discuss ecotoxicity and genotoxicity effects in organisms in response to exposure to arsenate (As V) in solution. Eco(geno)toxicity responses in Aliivibrio fischeri, Lytechinus variegatus, Daphnia magna, Skeletonema costatum and Vicia faba were analyzed by assessing different endpoints: biomass growth, peroxidase activity, mitotic index, micronucleus frequency, and lethality in accordance with the international protocols. Quantitative sensitivity relationships (QSR) between these endpoints were established in order to rank endpoint sensitivity. The results for the QSR values based on the lowest observed effect concentration (LOEC) ratios varied from 2 (for ratio of root peroxidase activity to leaf peroxidase activity) to 2286 (for ratio of higher plant biomass growth to root peroxidase activity). The QSR values allowed the following sensitivity ranking to be established: higher plant enzymatic activity>daphnids≈echinoderms>bacteria≈algae>higher plant biomass growth. The LOEC values for the mitotic index and micronucleus frequency (LOEC=0.25mgAsL(-1)) were similar to the lowest LOEC values observed in aquatic organisms. This approach to the QSR of different endpoints could form the basis for monitoring and predicting early effects of pollutants before they give rise to significant changes in natural community structures. Copyright © 2013 Elsevier Inc. All rights reserved.

Chaetognatha of the Namibian Upwelling Region: Taxonomy, Distribution and Trophic Position

PubMed Central

Bohata, Karolina; Koppelmann, Rolf

2013-01-01

In October 2010, the vertical distribution, biodiversity and maturity stages of Chaetognatha species were investigated at four stations located off Walvis Bay, Namibia. Seventeen species were detected and classified as pelagic, shallow-mesopelagic, deep-mesopelagic and bathypelagic species based upon the weighted mean depth derived from their average vertical distribution. High abundances of Chaetognatha were found in the upper 100 m at all stations of the Walvis Bay transect with a maximum value of 20837 ind. 1000 m−3 at the outer shelf station near the surface. The community was dominated by species of the Serratodentata group. Furthermore, the distribution of Chaetognatha did not seem to be influenced by low oxygen concentrations. Stable isotope ratios of carbon and nitrogen in Chaetognatha were determined for seven different areas located off northern Namibia. The values of δ15N ranged from 6.05 ‰ to 11.39 ‰, while the δ13C values varied between −23.89 ‰ and −17.03 ‰. The highest values for δ15N were observed at the Walvis Bay shelf break station. The lowest δ13C values were found at the Rocky Point offshore station, which was statistically different from all other areas. Stable isotopes of carbon and nitrogen were determined for four taxa (Sagitta minima, Planctonis group, Sagitta enflata, Sagitta decipiens). In this case, the δ15N values ranged from 6.17 ‰ to 10.38 ‰, whereas the δ13C values varied from −22.70 ‰ to −21.56 ‰. The lowest δ15N values were found for S. minima. The C- and N-content revealed maximum C-values for S. decipiens and maximum N-values for the Planctonis group. The C:N ratio of Chaetognatha ranged between 5.25 and 6.20. Overall, Chaetognatha are a diverse group in the pelagic food web of the Benguela Upwelling System and act as competitors of fish larvae and jelly fish by preying on copepods. PMID:23342016

Vacuum ultraviolet spectroscopy of the lowest-lying electronic state in subcritical and supercritical water

NASA Astrophysics Data System (ADS)

Marin, Timothy W.; Janik, Ireneusz; Bartels, David M.; Chipman, Daniel M.

2017-05-01

The nature and extent of hydrogen bonding in water has been scrutinized for decades, including how it manifests in optical properties. Here we report vacuum ultraviolet absorption spectra for the lowest-lying electronic state of subcritical and supercritical water. For subcritical water, the spectrum redshifts considerably with increasing temperature, demonstrating the gradual breakdown of the hydrogen-bond network. Tuning the density at 381 °C gives insight into the extent of hydrogen bonding in supercritical water. The known gas-phase spectrum, including its vibronic structure, is duplicated in the low-density limit. With increasing density, the spectrum blueshifts and the vibronic structure is quenched as the water monomer becomes electronically perturbed. Fits to the supercritical water spectra demonstrate consistency with dimer/trimer fractions calculated from the water virial equation of state and equilibrium constants. Using the known water dimer interaction potential, we estimate the critical distance between molecules (ca. 4.5 Å) needed to explain the vibronic structure quenching.

Vacuum ultraviolet spectroscopy of the lowest-lying electronic state in subcritical and supercritical water

DOE PAGES

Marin, Timothy W.; Janik, Ireneusz; Bartels, David M.; ...

2017-05-17

The nature and extent of hydrogen bonding in water has been scrutinized for decades, including how it manifests in optical properties. Here we report vacuum ultraviolet absorption spectra for the lowest-lying electronic state of subcritical and supercritical water. For subcritical water, the spectrum redshifts considerably with increasing temperature, demonstrating the gradual breakdown of the hydrogen-bond network. Tuning the density at 381°C gives insight into the extent of hydrogen bonding in supercritical water. The known gas-phase spectrum, including its vibronic structure, is duplicated in the low-density limit. With increasing density, the spectrum blueshifts and the vibronic structure is quenched as themore » water monomer becomes electronically perturbed. Fits to the supercritical water spectra demonstrate consistency with dimer/trimer fractions calculated from the water virial equation of state and equilibrium constants. As a result, using the known water dimer interaction potential, we estimate the critical distance between molecules (ca. 4.5 Å) needed to explain the vibronic structure quenching.« less

Food, feeding and absorption efficiencies of the sand dollar, Mellita quinquiesperforata (Leske)

NASA Astrophysics Data System (ADS)

Lane, Jacqueline M.; Lawrence, John M.

1982-04-01

The sand dollar, Melitta quinquiesperforata, is a ciliary-mucoid feeder, selective for <62 μm (silt-clay) size fraction of surface sediments. Lipid is the primary component of the organic fraction of silt-clay; levels were highest in May and June (17%) and lowest in December and January (8%). Mellita absorbed primarily lipid from the silt-clay; absorption efficiency of all biochemical components was highest in May and June (67 and 61%) and lowest in December and January (negative values). M. quinquiesperforata fed almost continuously with rate of feeding being higher in small animals and at warmer, summer water temperatures. There was significantly more food in the gut at night than in the day.

Effect of Diwali Firecrackers on Air Quality and Aerosol Optical Properties over Mega City (Delhi) in India

NASA Astrophysics Data System (ADS)

Sateesh, M.; Soni, V. K.; Raju, P. V. S.

2018-06-01

In this paper, the variations of aerosol properties due to crackers burning during Diwali event (11th-18th 2012) over mega city Delhi were investigated. The sky radiometer POM-2 aerosol optical property data from Skynet-India along with ambient air pollution data were critically analyzed. The aerosol optical depth (AOD) at 500 nm was 1.60 on 13th November, the Diwali day, and its value a maximum of 1.84 on 16th November. Due to stable atmosphere over Delhi during post Diwali, aerosols accumulate and remain in the atmosphere for longer time, which leads to higher AOD on 16th November. A lower value of single-scattering albedo (SSA) was observed at a longer wavelength (1020 nm) during the entire period that clearly indicates the dominance of absorbing-type black carbon aerosol. SSA showed a steep decrease after 16th November. Asymmetry parameter decreased to a maximum of 0.79 for the shorter wavelength at 340 nm and 0.632 is reported at the higher wavelength 1020 nm. Asymmetry parameter showed a decrease in value just after Diwali on 14th November, this suggesting the dominance of fine-mode aerosol from anthropogenic activities. The lowest value of the refractive index (1.4527) on 14th and 15th November indicates the higher loading of absorbing-type aerosol which may be associated with firecracker burning of Diwali festival. The significant correlation with the value of r = 0.9 was observed between sky radiometer and MODIS AOD with a standard deviation of 0.31 and an RMSE of 0.17 during the event. Radiative forcing and heating rate were estimated using SBDART. The maximum average concentrations 2641 and 1876 μg/m3 of PM10 and PM2.5, respectively, were observed on the Diwali night. A highest of 109 ppb surface ozone was reported in the night at 23:00 IST, which can be attributed to burning of the firecrackers.

[Oxidative metabolism of main and accessory olfactory bulbs, limpic system and hypothalamus during the estral cycle of the rat (author's transl)].

PubMed

Sánchez-Criado, J E

1979-06-01

The in vitro oxidative metabolism of hypothalamus, olfactory and limbic systems from female rats in the estrous cycle have been measured. The accessory olfactory bulb becomes most active during diestrous when the hypothalamus reaches its lowest values.

Analysis, comparison, and contrast of two primary maintenance contracting techniques used by the Florida Department of Transportation [summary].

DOT National Transportation Integrated Search

2016-12-01

A common method of government contracting is seeking the lowest bid that meets project specifications. While this assures that money is saved upfront, it may not ensure other project values, such as delivery time, ability to address unforeseen situat...

Analysis of dermoscopy teaching modalities in United States dermatology residency programs

PubMed Central

Chen, Yun An; Rill, Joanne; Seiverling, Elizabeth V.

2017-01-01

The use of dermoscopy in dermatology residency programs is on the rise (over 94% of chief residents reported using a dermatoscope in 2013) [1]. Despite increased use (100% of our surveyed residents reported using a dermatoscope), dermoscopy training is one of the aspects of United States dermatology residency training with the lowest resident satisfaction [2]. Diagnostic accuracy with dermoscopy is highly correlated with the amount of dermoscopy training the user has undertaken [3]. We sought to analyze dermoscopy use in US Dermatology residencies to better understand resident dermoscopy utilization and teaching modalities. We found residents learn dermoscopy via multiple teaching modalities. The most commonly reported dermoscopy teaching modality was didactic lectures, followed by time in clinic with a dermoscopy expert. Of the different teaching modalities, time in the clinic with a dermoscopy expert was reported to be the most effective. We also found that the majority of dermatology residents receive didactic dermoscopy lectures and clinical dermoscopy training on the differentiation of benign nevi from melanoma using dermoscopy, the detection of basal cell carcinoma, and the identification of seborrheic keratosis. However, few residents receive dedicated training on the use of dermoscopy in the evaluation of inflammatory dermatoses and skin infections despite dermoscopy’s demonstrated value in both areas [4–7]. PMID:29085718

The black hole candidate MAXI J1659-152 in and towards quiescence in X-ray and radio

NASA Astrophysics Data System (ADS)

Jonker, P. G.; Miller-Jones, J. C. A.; Homan, J.; Tomsick, J.; Fender, R. P.; Kaaret, P.; Markoff, S.; Gallo, E.

2012-07-01

In this paper we report on Expanded Very Large Array radio and Chandra and Swift X-ray observations of the outburst decay of the transient black hole candidate MAXI J1659-152 in 2011. We discuss the distance to the source taking the high inclination into account and conclude that the source distance is probably 6 ± 2 kpc. The lowest observed flux corresponds to a luminosity of ? erg s-1. This, together with the orbital period of 2.4 h reported in the literature, suggests that the quiescent X-ray luminosity is higher than predicted on the basis of the orbital period-quiescent X-ray luminosity relationship. It is more in line with that expected for a neutron star, although the outburst spectral and timing properties reported in the literature strongly suggest that MAXI J1659-152 harbours a black hole. This conclusion is subject to confirmation of the lowest observed flux as the quiescent flux. The relation between the accretion and ejection mechanisms can be studied using the observed correlation between the radio and X-ray luminosities as these evolve over an outburst. We determine the behaviour of MAXI J1659-152 in the radio-X-ray diagram at low X-ray luminosities using the observations reported in this paper and at high X-ray luminosities using values reported in the literature. At high X-ray luminosities, the source lies closer to the sources that follow a correlation index steeper than 0.6-0.7. However, when compared to other sources that follow a steeper correlation index, the X-ray luminosity in MAXI J1659-152 is also lower. The latter can potentially be explained by the high inclination of MAXI J1659-152 if the X-ray emission comes from close to the source and the radio emission is originating in a more extended region. However, it is probable that the source was not in the canonical low-hard state during these radio observations and this may affect the behaviour of the source as well. At intermediate X-ray luminosities, the source makes the transition from the radio underluminous sources in the direction of the relation traced by the 'standard' correlation similar to what has been reported for H 1743-322 in the literature. However, MAXI J1659-152 remains underluminous with respect to this 'standard' correlation.

When the lowest energy does not induce native structures: parallel minimization of multi-energy values by hybridizing searching intelligences.

PubMed

Lü, Qiang; Xia, Xiao-Yan; Chen, Rong; Miao, Da-Jun; Chen, Sha-Sha; Quan, Li-Jun; Li, Hai-Ou

2012-01-01

Protein structure prediction (PSP), which is usually modeled as a computational optimization problem, remains one of the biggest challenges in computational biology. PSP encounters two difficult obstacles: the inaccurate energy function problem and the searching problem. Even if the lowest energy has been luckily found by the searching procedure, the correct protein structures are not guaranteed to obtain. A general parallel metaheuristic approach is presented to tackle the above two problems. Multi-energy functions are employed to simultaneously guide the parallel searching threads. Searching trajectories are in fact controlled by the parameters of heuristic algorithms. The parallel approach allows the parameters to be perturbed during the searching threads are running in parallel, while each thread is searching the lowest energy value determined by an individual energy function. By hybridizing the intelligences of parallel ant colonies and Monte Carlo Metropolis search, this paper demonstrates an implementation of our parallel approach for PSP. 16 classical instances were tested to show that the parallel approach is competitive for solving PSP problem. This parallel approach combines various sources of both searching intelligences and energy functions, and thus predicts protein conformations with good quality jointly determined by all the parallel searching threads and energy functions. It provides a framework to combine different searching intelligence embedded in heuristic algorithms. It also constructs a container to hybridize different not-so-accurate objective functions which are usually derived from the domain expertise.

When the Lowest Energy Does Not Induce Native Structures: Parallel Minimization of Multi-Energy Values by Hybridizing Searching Intelligences

PubMed Central

Lü, Qiang; Xia, Xiao-Yan; Chen, Rong; Miao, Da-Jun; Chen, Sha-Sha; Quan, Li-Jun; Li, Hai-Ou

2012-01-01

Background Protein structure prediction (PSP), which is usually modeled as a computational optimization problem, remains one of the biggest challenges in computational biology. PSP encounters two difficult obstacles: the inaccurate energy function problem and the searching problem. Even if the lowest energy has been luckily found by the searching procedure, the correct protein structures are not guaranteed to obtain. Results A general parallel metaheuristic approach is presented to tackle the above two problems. Multi-energy functions are employed to simultaneously guide the parallel searching threads. Searching trajectories are in fact controlled by the parameters of heuristic algorithms. The parallel approach allows the parameters to be perturbed during the searching threads are running in parallel, while each thread is searching the lowest energy value determined by an individual energy function. By hybridizing the intelligences of parallel ant colonies and Monte Carlo Metropolis search, this paper demonstrates an implementation of our parallel approach for PSP. 16 classical instances were tested to show that the parallel approach is competitive for solving PSP problem. Conclusions This parallel approach combines various sources of both searching intelligences and energy functions, and thus predicts protein conformations with good quality jointly determined by all the parallel searching threads and energy functions. It provides a framework to combine different searching intelligence embedded in heuristic algorithms. It also constructs a container to hybridize different not-so-accurate objective functions which are usually derived from the domain expertise. PMID:23028708

Analysis on storage off-gas emissions from woody, herbaceous, and torrefied biomass

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tumuluru, Jaya Shankar; Lim, C. Jim; Bi, Xiaotao T.

Wood chips, torrefied wood chips, ground switchgrass, and wood pellets were tested for off-gas emissions during storage. Storage canisters with gas-collection ports were used to conduct experiments at room temperature of 20 °C and in a laboratory oven set at 40 °C. Commercially-produced wood pellets yielded the highest carbon monoxide (CO) emissions at both 20 and 40 °C (1600 and 13,000 ppmv), whereas torrefied wood chips emitted the lowest of about <200 and <2000 ppmv. Carbon dioxide (CO₂) emissions from wood pellets were 3000 ppmv and 42,000 ppmv, whereas torrefied wood chips registered at about 2000 and 25,000 ppmv, atmore » 20 and 40 °C at the end of 11 days of storage. CO emission factors (milligrams per kilogram of biomass) calculated were lowest for ground switchgrass and torrefied wood chips (2.68 and 4.86 mg/kg) whereas wood pellets had the highest CO of about 10.60 mg/kg, respectively, at 40 °C after 11 days of storage. In the case of CO₂, wood pellets recorded the lowest value of 55.46 mg/kg, whereas switchgrass recorded the highest value of 318.72 mg/kg. This study concludes that CO emission factor is highest for wood pellets, CO₂ is highest for switchgrass and CH₄ is negligible for all feedstocks except for wood pellets, which is about 0.374 mg/kg at the end of 11-day storage at 40 °C.« less

Analysis on storage off-gas emissions from woody, herbaceous, and torrefied biomass

DOE PAGES

Tumuluru, Jaya Shankar; Lim, C. Jim; Bi, Xiaotao T.; ...

2015-03-02

Wood chips, torrefied wood chips, ground switchgrass, and wood pellets were tested for off-gas emissions during storage. Storage canisters with gas-collection ports were used to conduct experiments at room temperature of 20 °C and in a laboratory oven set at 40 °C. Commercially-produced wood pellets yielded the highest carbon monoxide (CO) emissions at both 20 and 40 °C (1600 and 13,000 ppmv), whereas torrefied wood chips emitted the lowest of about <200 and <2000 ppmv. Carbon dioxide (CO₂) emissions from wood pellets were 3000 ppmv and 42,000 ppmv, whereas torrefied wood chips registered at about 2000 and 25,000 ppmv, atmore » 20 and 40 °C at the end of 11 days of storage. CO emission factors (milligrams per kilogram of biomass) calculated were lowest for ground switchgrass and torrefied wood chips (2.68 and 4.86 mg/kg) whereas wood pellets had the highest CO of about 10.60 mg/kg, respectively, at 40 °C after 11 days of storage. In the case of CO₂, wood pellets recorded the lowest value of 55.46 mg/kg, whereas switchgrass recorded the highest value of 318.72 mg/kg. This study concludes that CO emission factor is highest for wood pellets, CO₂ is highest for switchgrass and CH₄ is negligible for all feedstocks except for wood pellets, which is about 0.374 mg/kg at the end of 11-day storage at 40 °C.« less

Nutritional Physiology of the Khapra Beetle, Trogoderma granarium Everts (Coleoptera: Dermestidae) Fed on Various Barley Cultivars.

PubMed

Seifi, S; Naseri, B; Razmjou, J

2016-02-01

The Khapra beetle, Trogoderma granarium Everts (Coleoptera: Dermestidae), is known as one of the mostserious pests of grains in many parts of the world. In this study, the effect of nine barley cultivars (‘Bahman’,‘CB-84-10’, ‘Fajr 30’, ‘Makuyi’, ‘Nosrat’, ‘Yousof’, ‘13A1’, ‘18A1’, and ‘19 A1’) and a wheat cultivar (‘MV17’, as a control) was determined on the nutritional indices and digestive enzymatic activity of T. granarium at 33 6 1C,relative humidity of 6565%, and a photoperiod of 14:10 (L:D) h. The highest and lowest values of larval weight gain of sixth instar were detected on wheat (0.757±0.068 mg) and cultivar Bahman (0.342±0.071 mg). Also, T. granarium larvae fed on cultivar Bahman had the lowest value of efficiency of conversion of ingested food(10.90±2.09%) as compared with wheat and other barley cultivars. Also, the highest midgut amylolytic and proteolytic activities of sixth instar were on cultivar Bahman (0.364±0.024 mU/mg and 80.54±1.73 U/mg, respectively)and the lowest activities were on cultivar Nosrat (0.043±0.004 mU/mg and 7.15±0.01 U/mg, respectively).It is concluded that barley cultivar Bahman was the most unsuitable host for feeding of T. granarium.

Health and mineral nutrition status of yaks in southern Mustang, Nepal.

PubMed

Kumagai, Hajime; Nakajima, Mitsumi; Anzai, Hiroki; Sakai, Takashi; Oishi, Kazato; Hirooka, Hiroyuki; Shah, Manoj Kumar

2017-08-01

Biochemical values and mineral concentrations in blood plasma were investigated to evaluate the statuses of health and mineral nutrition among yaks in Mustang District, Nepal. In total, 118 plasma samples of female yaks collected in April and September/October of 2013-2015 were offered. Seventy-four percent of yaks showed lower plasma total-cholesterol concentrations than the lowest limit of reference range (100 mg/dL) and the values in spring (83.41 mg/dL) were lower (P < 0.05) than those in autumn (95.05 mg/dL). All the yaks had lower plasma albumin concentrations than the lowest limit of reference range (3.0 g/dL) and 66% of yaks showed lower plasma inorganic phosphorus concentrations than the critical level of phosphorus deficiency (4.5 mg/dL). Thirty-five percent of yaks showed lower plasma calcium concentrations than the lowest limit of normal range (8 mg/dL) and the concentrations were lower in spring than in autumn (P < 0.01). Seventy-five percent of yaks presented lower copper concentrations than the critical level (0.65 mg/L) and the concentrations were lower in spring than in autumn (P < 0.01). Since the low plasma total-cholesterol might have indicated shortage of dry matter and energy intake, attention should be paid to the nutritional statuses of energy, phosphorus, calcium and copper in winter and early spring. © 2016 Japanese Society of Animal Science.

The effect of silver (Ag) addition to mechanical and electrical properties of copper alloy (Cu) casting product

NASA Astrophysics Data System (ADS)

Felicia, Dian M.; Rochiem, R.; Laia, Standley M.

2018-04-01

Copper have good mechanical properties and good electrical conductivities. Therefore, copper usually used as electrical components. Silver have better electrical conductivities than copper. Female contact resistor is one of the electrical component used in circuit breaker. This study aims to analyze the effect of silver addition to hardness, strength, and electric conductivity properties of copper alloy. This study uses variation of 0; 0.035; 0.07; 0.1 wt. % Ag (silver) addition to determine the effect on mechanical properties and electrical properties of copper alloy through sand casting process. Modelling of thermal analysis and structural analysis was calculated to find the best design for the sand casting experiments. The result of Cu-Ag alloy as cast will be characterized by OES test, metallography test, Brinell hardness test, tensile test, and LCR meter test. The result of this study showed that the addition of silver increase mechanical properties of Cu-Ag. The maximum hardness value of this alloy is 83.1 HRB which is Cu-0.01 Ag and the lowest is 52.26 HRB which is pure Cu. The maximum strength value is 153.2 MPa which is Cu-0.07 Ag and the lowest is 94.6 MPa which is pure Cu. Silver addition decrease electrical properties of this alloy. The highest electric conductivity is 438.98 S/m which is pure Cu and the lowest is 52.61 S.m which is Cu-0.1 Ag.

The undergraduate preparation of dentists: Confidence levels of final year dental students at the School of Dentistry in Cardiff.

PubMed

Gilmour, A S M; Welply, A; Cowpe, J G; Bullock, A D; Jones, R J

2016-09-23

Objective To investigate the self-reported confidence and preparedness of final year undergraduate students in undertaking a range of clinical procedures.Methods A questionnaire was distributed to final year dental students at Cardiff University, six months prior to graduation. Respondents rated their confidence in undertaking 39 clinical procedures using a 5-point scale (1 = can undertake on own with confidence, 5 = unable to undertake). Students also responded yes/no to experiencing four difficulties and to three statements about general preparedness.Results 71% (N = 51) responded of which 55% (N = 28) were female. Over half reported being 'anxious that the supervisor was not helping enough' (57%) and 'relying heavily on supervisor for help' (53%). Eighty percent 'felt unprepared for the clinical work presented' and gender differences were most notable here (male: 65% N = 33; females: 93% N = 47). Mean confidence scores were calculated for each clinical procedure (1 = lowest; 5 = highest). Confidence was highest in performing 'simple scale' and 'fissure sealant' (mean-score = 5). Lowest scores were reported for 'surgical extractions involving a flap (mean-score = 2.28)', 'simple surgical procedures' (mean-score = 2.58) and the 'design/fit/adjustment of orthodontic appliances' (mean-score = 2.88).Conclusions As expected complex procedures that were least practised scored the lowest in overall mean confidence. Gender differences were noted in self-reported confidence for carrying out treatment unsupervised and feeling unprepared for clinical work.

Black chrome on commercially electroplated tin as a solar selecting coating

NASA Technical Reports Server (NTRS)

Mcdonald, G. E.

1977-01-01

The reflectance properties of black chrome electroplated on commercially electroplated tin were measured for various black chrome plating times for both the solar and infrared spectrum. The values of absorptance and emittance were calculated from the measured reflectance values. The results indicate that the optimum combination of the highest absorptance in the solar region and the lowest emittance in the infrared of the black chrome plated on commercially electroplated tin is obtained for a black chrome plating time of between one and two minutes.

Theoretical study of triplet state properties of free-base porphin

NASA Astrophysics Data System (ADS)

Loboda, Oleksandr; Tunell, Ingvar; Minaev, Boris; Ågren, Hans

2005-06-01

This paper presents results and analysis of various properties of the triplet state of free-base porphin (FBP) as calculated by density-functional theory. The radiative lifetime of phosphorescence lines and microwave signals in optical detection of magnetic resonance (ODMR) spectra are obtained using the B3LYP hybrid density-functional and the quadratic response method. The zero-field splitting (ZFS) in the lowest triplet state, a3 B2u, of FBP is calculated as an expectation value of spin-spin coupling operator using the self-consistent field wavefunction. The second-order contribution to ZFS from the spin-orbit coupling operator is found to be almost negligible. The interpretation of the ODMR spectrum is completed by computing the hyperfine tensors of the 14N, 13C and hydrogen atoms in the lowest triplet state. The most intense phosphorescence emission corresponds to the Tz-spin-sublevel of the a3 B2u state, where the z-axis lies in the N-H direction of the FBP molecule in a qualitative agreement with ODMR data. The results indicate that the observed decay of the lowest triplet state of FBP molecule is determined by non-radiative deactivation. The calculated radiative rate constant for the Tz-spin-sublevel kz = 2.65 × 10-3 s-1 is in agreement with the value kz ≃ 2 × 10-3 s-1, estimated by van Dorp et al. [W. van Dorp, W. Schoemaker, M. Soma, J. van der Waals, Mol. Phys. 30 (1975) 1701] from kinetic analysis of microwave-induced fluorescent signals. The correct prediction of the spin quantization axis of the most active spin sublevel and of its radiative lifetime in the lowest triplet state of the FBP molecule is taken as a proof of capability of the quadratic response time-dependent density-functional theory.

Epitaxial growth of GaSb on V-grooved Si (001) substrates with an ultrathin GaAs stress relaxing layer

NASA Astrophysics Data System (ADS)

Li, Qiang; Lai, Billy; Lau, Kei May

2017-10-01

We report epitaxial growth of GaSb nano-ridge structures and planar thin films on V-groove patterned Si (001) substrates by leveraging the aspect ratio trapping technique. GaSb was deposited on {111} Si facets of the V-shaped trenches using metal-organic chemical vapor deposition with a 7 nm GaAs growth initiation layer. Transmission electron microscopy analysis reveals the critical role of the GaAs layer in providing a U-shaped surface for subsequent GaSb epitaxy. A network of misfit dislocations was uncovered at the GaSb/GaAs hetero-interface. We studied the evolution of the lattice relaxation as the growth progresses from closely pitched GaSb ridges to coalesced thin films using x-ray diffraction. The omega rocking curve full-width-at-half-maximum of the resultant GaSb thin film is among the lowest values reported by molecular beam epitaxy, substantiating the effectiveness of the defect necking mechanism. These results thus present promising opportunities for the heterogeneous integration of devices based on 6.1 Å family compound semiconductors.

Novel Solid-State Solar Cell Based on Hole-Conducting MOF-Sensitizer Demonstrating Power Conversion Efficiency of 2.1.

PubMed

Ahn, Do Young; Lee, Deok Yeon; Shin, Chan Yong; Bui, Hoa Thi; Shrestha, Nabeen K; Giebeler, Lars; Noh, Yong-Young; Han, Sung-Hwan

2017-04-19

This work reports on designing of first successful MOF-sensitizer based solid-state photovoltaic device, perticularly with a meaningful output power conversion efficiency. In this study, an intrinsically conductive cobalt-based MOFs (Co-DAPV) formed by the coordination between Co (II) ions and a redox active di(3-diaminopropyl)-viologen (i.e., DAPV) ligand is investigated as sensitizer. Hall-effect measurement shows p-type conductivity of the Co-DAPV film with hole mobility of 0.017 cm 2 V -1 s -1 , suggesting its potential application as hole transporting sensitizer. Further, the energy levels of the highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO) of Co-DAPV are well-matched to be suitably employed for sensitizing TiO 2 . Thus, by layer-by-layer deposition of hole conducting MOF-sensitizer onto mesoporous TiO 2 film, a power conversion efficiency of as high as 2.1% is achieved, which exceeds the highest efficiency values of MOF-sensitized liquid-junction solar cells reported so far.

Respiratory load perception in overweight and asthmatic children.

PubMed

MacBean, Victoria; Wheatley, Lorna; Lunt, Alan C; Rafferty, Gerrard F

2017-05-01

Overweight asthmatic children report greater symptoms than normal weight asthmatics, despite comparable airflow obstruction. This has been widely assumed to be due to heightened perception of respiratory effort. Three groups of children (healthy weight controls, healthy weight asthmatics, overweight asthmatics) rated perceived respiratory effort throughout an inspiratory resistive loading protocol. Parasternal intercostal electromyogram was used as an objective marker of respiratory load; this was expressed relative to tidal volume and reported as a ratio of the baseline value (neuroventilatory activity ratio (NVEAR)). Significant increases in perception scores (p<0.0001), and decreases in NVEAR (p<0.0001) were observed from lowest to highest resistive load. Higher BMI increased overall perception scores, with no influence of asthma or BMI-for-age percentile on the resistance-perception relationships. These data, indicating elevated overall respiratory effort in overweight asthmatic children but comparable responses to dynamic changes in load, suggest that the greater disease burden in overweight asthmatic children may be due to altered respiratory mechanics associated with increased body mass. Copyright © 2017 Elsevier B.V. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Feldman, U.; Space Science Division, Naval Research Laboratory, Washington, DC 20375-5320; Doschek, G.A.

We list observed parity-forbidden and spin-forbidden lines in the 500-1600 A range emitted by solar coronal plasmas and derive improved energy levels from their wavelengths. The lines, emitted by astrophysical abundant elements, belong to transitions within the ground configurations of the type ns{sup 2} np {sup k}, for n = 2, 3 and k = 0-5, and between the lowest term of the first excited configuration 2s2p {sup k+1} and the 2s{sup 2}2p {sup k} ground configurations for k = 0, 1, 2. For each line we give the newly measured wavelength, and the measured or predicted wavelength from themore » NIST Atomic Spectra Database (ASD) (which except for a few cases includes the previously reported compilation of Kaufman and Sugar [J. Phys. Chem. Ref. Data 15 (1986) 321]), and the values of the transition probability taken from the ASD and CHIANTI database. The list contains measured wavelengths of 136 lines of which over 100 were not available for the Kaufman and Sugar compilation. In addition we provide energy levels that were derived from the reported lines.« less

Low plastic ingestion rate in Atlantic cod (Gadus morhua) from Newfoundland destined for human consumption collected through citizen science methods.

PubMed

Liboiron, Max; Liboiron, France; Wells, Emily; Richárd, Natalie; Zahara, Alexander; Mather, Charles; Bradshaw, Hillary; Murichi, Judyannet

2016-12-15

Marine microplastics are a contaminant of concern because their small size allows ingestion by a wide range of marine life. Using citizen science during the Newfoundland recreational cod fishery, we sampled 205 Atlantic cod (Gadus morhua) destined for human consumption and found that 5 had eaten plastic, an ingestion prevalence rate of 2.4%. This ingestion rate for Atlantic cod is the second lowest recorded rate in the reviewed published literature (the lowest is 1.4%), and the lowest for any fish in the North Atlantic. This is the first report for plastic ingestion in fish in Newfoundland, Canada, a province dependent on fish for sustenance and livelihoods. Copyright © 2016 Elsevier Ltd. All rights reserved.

Anaerobic digestion of wastewater from the fruit juice industry: experiments and modeling.

PubMed

Zerrouki, Souhaib; Rihani, Rachida; Bentahar, Fatiha; Belkacemi, Khaled

2015-01-01

Anaerobic digestion of wastewater from the fruit juice industry was carried out in a batch digester. To study the effect of the pH values as well as the nutrient medium on the fermentation process, different parameters were monitored under mesophilic temperature, such as cumulative biogas volume, chemical oxygen demand (COD), total sugar, and biomass growth. It was found that for all cases, the COD concentration decreased with time. The lowest value reached was obtained when the nutrient medium was added; it was about 110 g/L after 480 h. In such cases, the COD removal reached about 80%; the highest cumulative biogas volume of about 5,515.8 NmL was reached after 480 h testing; and the lowest value reached was about 2,862.3 NmL in the case of peach-substrate containing sodium sulfite. The addition of nutrient medium improved the cumulative biogas production as well as the COD abatement. Measurement of the biogas composition highlighted three gaseous components, namely, methane (56.52%), carbon dioxide (20.14%), and hydrogen sulfide (23.34%). The modified Gompertz equation and the first-order kinetic model were used to describe the cumulative biogas production and the organic matter removal, respectively. A good agreement was found between simulated and experimental data.

Potential of antioxidant and toxicity of some medical plants used by sub-ethnic communities of Bahau in East Kalimantan

NASA Astrophysics Data System (ADS)

Rohim, P.; Arung, E. T.; Kusuma, I. W.

2018-04-01

The purpose of this research is to assay the potential antioxidant and toxicity of several plants from Bahau, a sub-ethnic in East Kalimantan in regard to their utilization as traditional medicines. This research includes phytochemical analysis, DPPH radical and superoxide radical scavenging activity as well as toxicity assay using Artemiasalina shrimp larvae. The results of the extraction showed the highest yield was 2,91% obtained from avung tanaq (Ficus uncinata), while the lowest is 1.14% obtained from tevoqsalah (Saccharum sp.) species. The result of phytochemicals showed that all plants contain alkaloid and carbohydrate. While carotenoids, saponins, triterpenoids and steroids were absence in all plant extracts. The DPPH radical scavenging activity test showed that the lowest IC50 value of kayog kue (Dictamnus albus) by 23.96 μg/mL. The superoxide radical scavenging activity assay showed IC50 values of all extract samples were >100 μg/mL. The toxicity assay showed that LC50 values of all samples of extract tested were >1000 μg/mL. The present research suggested good potential activity of some plants from Bahau ethnic and further research oriented to wide uses of the plants as herbal products is needed.

Effects of indigo carmine intravenous injection on oxygen reserve index (ORi™) measurement.

PubMed

Isosu, Tsuyoshi; Yoshida, Keisuke; Oishi, Rieko; Imaizumi, Tsuyoshi; Iseki, Yuzo; Sanbe, Norie; Ikegami, Yukihiro; Obara, Shinju; Kurosawa, Shin; Murakawa, Masahiro

2017-10-03

To retrospectively investigate the effects of indigo carmine intravenous injection on oxygen reserve index (ORi™) in 20 patients who underwent elective gynecologic surgery under general anesthesia. The study subjects were patients who underwent elective gynecologic surgery under general anesthesia between April 2016 and January 2017, and were administered a 5-ml intravenous injection of 0.4% indigo carmine for clinical purposes during surgery with ORi monitoring. Changes in ORi within 20 min after indigo carmine injection were observed. A relevant decrease in ORi was defined as ≥ 10% reduction in ORi from pre-injection level. ORi rapidly decreased after indigo carmine intravenous injection in all patients. In 10 of 19 patients, ORi decreased to 0 after indigo carmine injection. The median lowest value of ORi was 0 (range 0-0.16) and the median time to reach the lowest value of ORi was 2 min (range 1-4 min) after injection. ORi values returned to pre-injection levels within 20 min in 13 of 19 patients, and the median time to return to pre-injection levels was 10 min (range 6-16 min) after injection. During ORi monitoring it is necessary to consider the rapid reduction in ORi after intravenous injection of indigo carmine.

Larvicidal, pupicidal and adulticidal activities of non-polar solvent extract of Cymbopogon nardus (Linn.) whole plant against a mosquito, Culex quinquefasciatus (Say.).

PubMed

Ilahi, Ikram; Yousafzai, Ali Muhammad

2017-11-01

The present research is aimed to investigate the susceptibility of Cx. quinquefasciatus larvae (2nd and 4th instars), pupae and adults during exposure to various concentrations of C. nardus n-hexane extract. Increase in mortality of larvae and pupae was observed with increase in concentration of the extract solution (R2>0.90). LC50 values of extract for 2nd and 4th instar larvae were 451.8 and 599.6 ppm, respectively. The LC90 values of extract for 2nd and 4th instar larvae were 2519.6 and 3017.7 ppm, respectively. The LC50 and LC90 values of extract during pupicidal activity were 1307.7 and 2257.9 ppm, respectively. During CDC bottle bioassay, mosquito adult knockdown was observed after exposure to various concentrations (0.15% to 1.25%) of C. nardus n-hexane extract. The KDT50 values at highest (1.25%) and lowest (0.15%) concentrations were 100.9 and 184.2 minutes, respectively. After 24 hours exposure period, the highest extract concentration (1.25%) caused 62.5±6.5% mortality. During filter paper impregnation bioassay, the KDT50 value at highest concentration (0.13 mg/cm2) was 94.4 minutes and at lowest concentration (0.017 mg/cm²) was 178.9 minutes. KDT90 values at these concentrations were 176.7 and 290.1 minutes, respectively. After 24 hours of recovery period, the filter papers impregnated with highest extract concentration (0.13mg/cm2) caused 60±8.2% mortality.

An evaluation of freshwater mussel toxicity data in the derivation of water quality guidance and standards for copper

USGS Publications Warehouse

March, F.A.; Dwyer, F.J.; Augspurger, T.; Ingersoll, C.G.; Wang, N.; Mebane, C.A.

2007-01-01

The state of Oklahoma has designated several areas as freshwater mussel sanctuaries in an attempt to provide freshwater mussel species a degree of protection and to facilitate their reproduction. We evaluated the protection afforded freshwater mussels by the U.S. Environmental Protection Agency (U.S. EPA) hardness-based 1996 ambient copper water quality criteria, the 2007 U.S. EPA water quality criteria based on the biotic ligand model and the 2005 state of Oklahoma copper water quality standards. Both the criterion maximum concentration and criterion continuous concentration were evaluated. Published acute and chronic copper toxicity data that met American Society for Testing and Materials guidance for test acceptability were obtained for exposures conducted with glochidia or juvenile freshwater mussels. We tabulated toxicity data for glochidia and juveniles to calculate 20 species mean acute values for freshwater mussels. Generally, freshwater mussel species mean acute values were similar to those of the more sensitive species included in the U.S. EPA water quality derivation database. When added to the database of genus mean acute values used in deriving 1996 copper water quality criteria, 14 freshwater mussel genus mean acute values included 10 of the lowest 15 genus mean acute values, with three mussel species having the lowest values. Chronic exposure and sublethal effects freshwater mussel data available for four species and acute to chronic ratios were used to evaluate the criterion continuous concentration. On the basis of the freshwater mussel toxicity data used in this assessment, the hardness-based 1996 U.S. EPA water quality criteria, the 2005 Oklahoma water quality standards, and the 2007 U.S. EPA water quality criteria based on the biotic ligand model might need to be revised to afford protection to freshwater mussels. ?? 2007 SETAC.

Validity of self-reported family history of cancer: A systematic literature review on selected cancers.

PubMed

Fiederling, Jonas; Shams, Ahmad Zia; Haug, Ulrike

2016-10-01

Evidence regarding validity of self-reported family history of cancer (FHC) has been reviewed only for breast, colorectal, prostate, ovarian, endometrial and uterine cancer. We aimed to systematically review studies assessing validity of self-reported family history for the remaining cancer sites. We searched the Medline database for relevant studies published by January 2016. We extracted information on the study design and the positive predictive value (PPV) of self-reported FHC, defined as the proportion of reported cancer diagnoses among relatives that was confirmed by a reference standard (as a measure of over-reporting). We also extracted information on sensitivity of self-reported FHC (as a measure of underreporting). Overall, 21 studies were included that provided information on the PPV of self-reported FHC for relevant cancers and four studies also provided information on sensitivity. The PPV was highest (mostly >70%) for pancreatic, lung, thyroid and urinary system cancers and for leukemia and lymphoma, while it was lowest for stomach and liver cancer. Sensitivity was highest (>70%) for pancreatic cancer, lung cancer, brain cancer, melanoma, leukemia and lymphoma. For several cancers, sample sizes were low and the number of studies limited, particularly regarding sensitivity of self-reported FHC. In conclusion, for some cancers (e.g., pancreatic cancer, lung cancer, leukemia, lymphoma) self-reported FHC can be considered sufficiently valid to be useful, for example, in preventive counseling. For several cancers, it is not sufficiently studied or the pattern is inconsistent. This needs to be taken into account when using self-reported information about FHC in clinical practice or epidemiological research. © 2016 UICC.

Impact of smoking reduced nicotine content cigarettes on sensitivity to cigarette price: further results from a multi-site clinical trial.

PubMed

Smith, Tracy T; Cassidy, Rachel N; Tidey, Jennifer W; Luo, Xianghua; Le, Chap T; Hatsukami, Dorothy K; Donny, Eric C

2017-02-01

To assess the impact of a reduction in the nicotine content of cigarettes on estimated consumption of reduced nicotine cigarettes and usual brand cigarettes at a variety of hypothetical prices. Double-blind study with participants assigned randomly to receive cigarettes for 6 weeks that were either usual brand or an investigational cigarette with one of five nicotine contents. Ten sites across the United States. A total of 839 eligible adult smokers randomized from 2013 to 2014. Participants received their usual brand or an investigational cigarette with one of five nicotine contents: 15.8 (primary control), 5.2, 2.4, 1.3, or 0.4 mg/g. The Cigarette Purchase Task was completed at baseline and at the week 6 post-randomization visit. Compared with normal nicotine content controls, the lowest nicotine content (0.4 mg/g) reduced the number of study cigarettes participants estimated they would smoke at a range of prices [mean reduction relative to 15.8 mg/g at a price of $4.00/pack: 9.50, 95% confidence interval (CI) = 6.81,12.19]. The lowest nicotine content also reduced the maximum amount of money allocated to study cigarettes and the price at which participants reported they would stop buying study cigarettes [median reduction relative to 15.8 mg/g, 95% CI = $8.21 (4.27,12.15) per day and $0.44 (0.17,0.71) per cigarette, respectively]. A reduction in nicotine content to the lowest level also reduced the maximum amount of money allocated to usual brand cigarettes (median reduction relative to 15.8 mg/g: $4.39 per day, 95% CI = 1.88,6.90). In current smokers, a reduction in nicotine content may reduce cigarette consumption, reduce the reinforcement value of cigarettes and increase cessation if reduced nicotine content cigarettes were the only cigarette available for purchase. © 2016 Society for the Study of Addiction.

Effects of Pre and Post-Rigor Marinade Injection on Some Quality Parameters of Longissimus Dorsi Muscles

PubMed Central

Fadıloğlu, Eylem Ezgi; Serdaroğlu, Meltem

2018-01-01

Abstract This study was conducted to evaluate the effects of pre and post-rigor marinade injections on some quality parameters of Longissimus dorsi (LD) muscles. Three marinade formulations were prepared with 2% NaCl, 2% NaCl+0.5 M lactic acid and 2% NaCl+0.5 M sodium lactate. In this study marinade uptake, pH, free water, cooking loss, drip loss and color properties were analyzed. Injection time had significant effect on marinade uptake levels of samples. Regardless of marinate formulation, marinade uptake of pre-rigor samples injected with marinade solutions were higher than post rigor samples. Injection of sodium lactate increased pH values of samples whereas lactic acid injection decreased pH. Marinade treatment and storage period had significant effect on cooking loss. At each evaluation period interaction between marinade treatment and injection time showed different effect on free water content. Storage period and marinade application had significant effect on drip loss values. Drip loss in all samples increased during the storage. During all storage days, lowest CIE L* value was found in pre-rigor samples injected with sodium lactate. Lactic acid injection caused color fade in pre-rigor and post-rigor samples. Interaction between marinade treatment and storage period was found statistically significant (p<0.05). At day 0 and 3, the lowest CIE b* values obtained pre-rigor samples injected with sodium lactate and there were no differences were found in other samples. At day 6, no significant differences were found in CIE b* values of all samples. PMID:29805282

Effects of Pre and Post-Rigor Marinade Injection on Some Quality Parameters of Longissimus Dorsi Muscles.

PubMed

Fadıloğlu, Eylem Ezgi; Serdaroğlu, Meltem

2018-04-01

This study was conducted to evaluate the effects of pre and post-rigor marinade injections on some quality parameters of Longissimus dorsi (LD) muscles. Three marinade formulations were prepared with 2% NaCl, 2% NaCl+0.5 M lactic acid and 2% NaCl+0.5 M sodium lactate. In this study marinade uptake, pH, free water, cooking loss, drip loss and color properties were analyzed. Injection time had significant effect on marinade uptake levels of samples. Regardless of marinate formulation, marinade uptake of pre-rigor samples injected with marinade solutions were higher than post rigor samples. Injection of sodium lactate increased pH values of samples whereas lactic acid injection decreased pH. Marinade treatment and storage period had significant effect on cooking loss. At each evaluation period interaction between marinade treatment and injection time showed different effect on free water content. Storage period and marinade application had significant effect on drip loss values. Drip loss in all samples increased during the storage. During all storage days, lowest CIE L* value was found in pre-rigor samples injected with sodium lactate. Lactic acid injection caused color fade in pre-rigor and post-rigor samples. Interaction between marinade treatment and storage period was found statistically significant ( p <0.05). At day 0 and 3, the lowest CIE b* values obtained pre-rigor samples injected with sodium lactate and there were no differences were found in other samples. At day 6, no significant differences were found in CIE b* values of all samples.

[Density, size structure and reproductive activity of the pink conch Eustrombus gigas (Mesogastropoda: Strombidae) in Banco Chinchorro, Mexico].

PubMed

Cala, Yuself R; Navarrete, Alberto de Jesús; Ocaña, Frank A; Rivera, José Oliva

2013-12-01

The pink conch Eustrombus gigas is an important fisheries resource. At the regional level in the Caribbean, over-exploitation and habitat destruction have caused a decrease in the abundance of this resource. In order to provide necessary information for the species management in Mexico, this work aimed to analyze the total density, adult density, size structure and reproductive behavior of pink conch population at Banco Chinchorro during 2009-2010. Data from three seasons were obtained (rainy, dry and cold fronts periods) in three areas: Norte (North), Centro (Center) and Sur (South). The organisms were separated into two groups: (a) the criteria based upon legal harvest in Mexico: legal size conchs (siphonal length > 200 mm) and illegal size conchs (siphonal length < 200 mm), and (b) the criteria based upon sexual maturity using the 15 mm lip thickness standard: lip < 15 mm as juvenile conch and lip > or = 15 mm as adult conch. Copulation, spawning, egg masses and aggregations were evaluated as reproductive evidences. The highest total density was observed during the dry season with 384ind./ha, and the lowest during the rainy season with 127ind./ha. The highest density was reported at Sur (385ind./ha) and the lowest at Norte (198ind./ ha). The highest adult density was observed during the rainy season (8.33ind./ha), and the lowest occurred in the dry season (6.1 ind./ha). Adult density values were 5.55, 7.05 and 8.33ind./ha for Centro, Sur and Norte areas, respectively. Adult densities were lower than the threshold needed for reproduction, and 42% of the population may be vulnerable to fishing, as they had the minimum size for catch (Lsi 200 mm). Furthermore, only 2.2% of the population reached a Gl > 15 mm as sexual maturity indicator. During the study period, only six evidences of reproductive activity were observed. The smaller densities reported at Banco Chinchorro may cause reproduction events to be almost absent which in turn is sufficient evidence to show that the Allee Effect is acting on the queen conch population and there is an urgent need of fishery closure. Three important points were proposed for management of queen conch at Banco Chinchorro: total closure of fishing, systematic assessment of the conch population and the implementation of conch fishing refuge.

Sociodemographic status and self-reported BMI-related morbidity in Koreans.

PubMed

Lee, Kayoung

2010-03-01

This study examined whether the relationship between body mass index (BMI) and the morbidity of chronic diseases differs by marital status, education, and income level. From a nationally representative sample of 5,526 adults from the third Korean National Health and Nutrition Examination Survey (2005), data regarding measured height and weight to classify BMI category (< 23, 23-24.9, > or = 25), self-reported sociodemographics (marital status, education, income, age, sex, and residence area), health behaviors (smoking, alcohol use, exercise, sleep, stress perception, and depression), and morbidity from at least one chronic disease were collected. Education, income, and marital status were significantly associated with morbidity regardless of adjustment for BMI and health behaviors. After adjusting for BMI, other sociodemographic factors, and health behaviors, the odds ratio (95% confidence interval) of morbidity was 2.9 (2.4-3.7) for those in the married group and 2.9 (2.1-4.0) for those in the separated/divorced/widowed group, 2.0 (1.6-2.5) for those in the lowest education group, and 1.3 (1.2-1.6) for those in the lowest income group. When the BMI category and sociodemographic factors were combined, the odds ratios were elevated for those in the combination group with higher BMI and lower sociodemographic position. Korean subjects who were married, in the lowest education group, or in the lowest income level had a higher risk of morbidity in relation to BMI.

Social Inequality and Visual Impairment in Older People.

PubMed

Whillans, Jennifer; Nazroo, James

2018-03-02

Visual impairment is the leading cause of age-related disability, but the social patterning of loss of vision in older people has received little attention. This study's objective was to assess the association between social position and onset of visual impairment, to empirically evidence health inequalities in later life. Visual impairment was measured in 2 ways: self-reporting fair vision or worse (moderate) and self-reporting poor vision or blindness (severe). Correspondingly, 2 samples were drawn from the English Longitudinal Study on Ageing (ELSA). First, 7,483 respondents who had good vision or better at Wave 1; second, 8,487 respondents who had fair vision or better at Wave 1. Survival techniques were used. Cox proportional hazards models showed wealth and subjective social status (SSS) were significant risk factors associated with the onset of visual impairment. The risk of onset of moderate visual impairment was significantly higher for the lowest and second lowest wealth quintiles, whereas the risk of onset of severe visual impairment was significantly higher for the lowest, second, and even middle wealth quintiles, compared with the highest wealth quintile. Independently, lower SSS was associated with increased risk of onset of visual impairment (both measures), particularly so for those placing themselves on the lowest rungs of the social ladder. The high costs of visual impairment are disproportionately felt by the worst off elderly. Both low wealth and low SSS significantly increase the risk of onset of visual impairment.

Patient-reported sleep difficulty and cognitive function during the first year of dialysis.

PubMed

Kutner, Nancy G; Zhang, Rebecca; Huang, Yijian; Bliwise, Donald L

2008-01-01

Research in the general population indicates that sleep fragmentation is detrimental for cognitive function, but little attention has been given to this issue in dialysis patients. We hypothesized that patients with self-reported persistent sleep difficulty would have an increased risk of scoring lower on a cognitive function measure at follow-up compared to their score at baseline. Sleep difficulty and cognitive function were reported by a large national patient cohort near the start of dialysis and at a 9- to 12-month follow-up. Logistic regression was used to investigate the risk of scoring lower on a cognitive function measure at follow-up as a function of self-reported sleep difficulty, controlling for patients' sociodemographic, clinical and treatment characteristics, including depressed mood. At follow-up, cognitive function scores were lower among 35.8% of the cohort. Patients with self-reported persistent sleep difficulty had the lowest average cognitive function score. Men with reported persistent sleep difficulty, regardless of presence of depressed mood, had a significantly increased risk of a lower cognitive function score at follow-up. Women with reported persistent sleep difficulty as well as depressed mood had significantly increased risk of a lower cognitive function score. The potential impact of sleep difficulty and depressed mood on the cognitive function of dialysis patients emphasizes the importance of evaluating and treating these risks and highlights the value of continued research to improve our understanding and management of these issues.

Superconductivity in metastable phases of phosphorus-hydride compounds under high pressure

NASA Astrophysics Data System (ADS)

Flores Livas, Jose; Amsler, Maximilian; Sanna, Antonio; Heil, Christoph; Boeri, Lilia; Profeta, Gianni; Wolverton, Crhis; Goedecker, Stefan; Gross, E. K. U.

Recently, compressed phosphine was reported to metallize at pressures above 45 GPa, reaching a superconducting transition temperature (Tc) of 100 K at 200 GPa. However, neither the exact composition nor the crystal structure of the superconducting phase have been conclusively determined. In this work the phase diagram of PHn (n = 1 , 2 , 3 , 4 , 5 , 6) was extensively explored by means of ab initio crystal structure prediction methods. The results do not support the existence of thermodynamically stable PHn compounds, which exhibit a tendency for elemental decomposition at high pressure even when vibrational contributions to the free energies are taken into account. Although the lowest energy phases of PH1 , 2 , 3 display Tc's comparable to experiments, it remains questionable if the measured values of Tc can be fully attributed to a phase-pure compound of PHn. This work was done within the NCCR MARVEL project.

Vibration characteristics of 1/8-scale dynamic models of the space-shuttle solid-rocket boosters

NASA Technical Reports Server (NTRS)

Leadbetter, S. A.; Stephens, W.; Sewall, J. L.; Majka, J. W.; Barret, J. R.

1976-01-01

Vibration tests and analyses of six 1/8 scale models of the space shuttle solid rocket boosters are reported. Natural vibration frequencies and mode shapes were obtained for these aluminum shell models having internal solid fuel configurations corresponding to launch, midburn (maximum dynamic pressure), and near endburn (burnout) flight conditions. Test results for longitudinal, torsional, bending, and shell vibration frequencies are compared with analytical predictions derived from thin shell theory and from finite element plate and beam theory. The lowest analytical longitudinal, torsional, bending, and shell vibration frequencies were within + or - 10 percent of experimental values. The effects of damping and asymmetric end skirts on natural vibration frequency were also considered. The analytical frequencies of an idealized full scale space shuttle solid rocket boosted structure are computed with and without internal pressure and are compared with the 1/8 scale model results.

Instantaneous stroke volume in man during lower body negative pressure /LBNP/

NASA Technical Reports Server (NTRS)

Loeppky, J. A.; Richards, K. L.; Greene, E. R.; Eldridge, M. W.; Hoekenga, D. E.; Venters, M. D.; Luft, U. C.

1982-01-01

Results of an examination of the instantaneous time course of the stroke volume (SV) and cardiac output (Q) in response to the onset and release of -50 torr lower body negative pressure (LBNP) are reported. Six male subjects were sealed into a LBNP box up to the iliac crest while being monitored by echocardiograph for centerlamina blood velocity, fluid displacement, stroke volume, heart rate, and leg volume. Particular use was made of pulsed ultrasonic Doppler velocity meters for measuring the blood velocities and flow dynamics. Measurements were made of the subjects continuously beginning from 20 sec prior to and one min after LBNP onset and release. A linear fall in the SV was observed with LBNP at 49% of the baseline value after 33 sec. A 62% drop, the lowest, was detected after 8 min of LBNP. The leg volume was inversely related to Q for the duration of the experiment.

Experimental observation of an extremely dark material made by a low-density nanotube array.

PubMed

Yang, Zu-Po; Ci, Lijie; Bur, James A; Lin, Shawn-Yu; Ajayan, Pulickel M

2008-02-01

An ideal black material absorbs light perfectly at all angles and over all wavelengths. Here, we show that low-density vertically aligned carbon nanotube arrays can be engineered to have an extremely low index of refraction, as predicted recently by theory [Garcia-Vidal, F. J.; Pitarke, J. M.; Pendry, J. B. Phys. Rev. Lett. 1997, 78, 4289-4292] and, combined with the nanoscale surface roughness of the arrays, can produce a near-perfect optical absorption material. An ultralow diffused reflectance of 1 x 10(-7) measured from such arrays is an order-of-magnitude lower compared to commercial low-reflectance standard carbon. The corresponding integrated total reflectance of 0.045% from the nanotube arrays is three times lower than the lowest-ever reported values of optical reflectance from any material, making it the darkest man-made material ever.

Chemical composition and antibacterial activity of the essential oil from Agathis dammara (Lamb.) Rich fresh leaves.

PubMed

Chen, Zhifen; He, Daohang; Deng, Jingdan; Zhu, Jiaying; Mao, Qiuping

2015-01-01

The essential oil of fresh leaves from Agathis dammara (Lamb.) Rich was extracted using hydro-distillation, and GC-FID and GC-MS were used to analyse the essential oil. Nineteen compounds were identified, among which the major components were limonene (36.81%), β-bisabolene (33.43%) and β-myrcene (25.48%). In the antibacterial test, disc diffusion method and micro-well dilution assay proved that the essential oil had significant antibacterial activities. The inhibition zones against Staphylococcus aureus and Pseudomonas aeruginosa were 23.7 and 23 mm, respectively, which demonstrated that the inhibition effects were greater than positive control (10 μg/disc streptomycin). And the lowest MIC value of the essential oil was found against S. aureus (1.25 mg/mL) and Bacillus subtilis (1.25 mg/mL). This is the first report on the antibacterial activities of A. dammara essential oil.

Variation of magnetoimpedance of electrodeposited NiFe/Cu with deposition current density

NASA Astrophysics Data System (ADS)

Mishra, A. C.; Jha, A. K.

2017-12-01

An investigation about influence of deposition current density on electrodeposited magnetic film is reported in this paper. Ferromagnetic NiFe thin films were electrodeposited on copper wires of 100 μm diameter for various electrdepostion current densities ranging from 10 to 60 mA/cm2 maintaining equal thickness in all films. The composition of deposited film varied with deposition current density and in particular, a composition of Ni79Fe21 was achieved for a current density of 20 mA/cm2. The surface microstructure of the film deposited at the current density of 20 mA/cm2 was found to have excellent smoothness. The coercivity of the film was lowest and highest value of magnetoimpedance was measured for this film. The influence of current density on film composition and hence magnetic properties was attributed to the change of deposition mechanism.

Gravity resonance spectroscopy constrains dark energy and dark matter scenarios.

PubMed

Jenke, T; Cronenberg, G; Burgdörfer, J; Chizhova, L A; Geltenbort, P; Ivanov, A N; Lauer, T; Lins, T; Rotter, S; Saul, H; Schmidt, U; Abele, H

2014-04-18

We report on precision resonance spectroscopy measurements of quantum states of ultracold neutrons confined above the surface of a horizontal mirror by the gravity potential of Earth. Resonant transitions between several of the lowest quantum states are observed for the first time. These measurements demonstrate that Newton's inverse square law of gravity is understood at micron distances on an energy scale of 10-14  eV. At this level of precision, we are able to provide constraints on any possible gravitylike interaction. In particular, a dark energy chameleon field is excluded for values of the coupling constant β>5.8×108 at 95% confidence level (C.L.), and an attractive (repulsive) dark matter axionlike spin-mass coupling is excluded for the coupling strength gsgp>3.7×10-16 (5.3×10-16) at a Yukawa length of λ=20  μm (95% C.L.).

Reduction of shunt current in buffer-free IrMn based spin-valve structures

NASA Astrophysics Data System (ADS)

Kocaman, B.; Akdoğan, N.

2018-06-01

The presence of thick buffer layers in magnetic sensor devices decreases sensor sensitivity due to shunt currents. With this motivation, we produced IrMn-based spin-valve multilayers without using buffer layer. We also studied the effects of post-annealing and IrMn thickness on exchange bias field (HEB) and blocking temperature (TB) of the system. Magnetization measurements indicate that both HEB and TB values are significantly enhanced with post-annealing of IrMn layer. In addition, we report that IrMn thickness of the system strongly influences the magnetization and transport characteristics of the spin-valve structures. We found that the minimum thickness of IrMn layer is 6 nm in order to achieve the lowest shunt current and high blocking temperature (>300 K). We also investigated the training of exchange bias to check the long-term durability of IrMn-based spin-valve structures for device applications.

Revised Atomistic Models of the Crystal Structure of C-S-H with high C/S Ratio

NASA Astrophysics Data System (ADS)

Kovačević, Goran; Nicoleau, Luc; Nonat, André; Veryazov, Valera

2016-09-01

The atomic structure of calcium-silicate-hydrate (C1.67-S-Hx) has been studied. Atomistic C-S-H models suggested in our previous study have been revised in order to perform a direct comparison of energetic stability of the different structures. An extensive set of periodic structures of C-S-H with variation of water content was created, and then optimized using molecular dynamics with reactive force field ReaxFF and quantum chemical semiempirical method PM6. All models show organization of water molecules inside the structure of C-S-H. The new geometries of C-S-H, reported in this paper, show lower relative energy with respect to the geometries from the original definition of C-S-H models. Model that corresponds to calcium enriched tobermorite structure has the lowest relative energy and the density closest to the experimental values.

Inertial focusing dynamics in spiral microchannels

PubMed Central

Martel, Joseph M.; Toner, Mehmet

2012-01-01

This report details a comprehensive study of inertial focusing dynamics and particle behavior in low aspect ratio (h/w ∼ 1/1 to 1/8) spiral microchannels. A continuum of particle streak behavior is shown with longitudinal, cross-sectional, and velocity resolution, yielding a large analyzed parameter space. The dataset is then summarized and compared to prior results from both straight microchannels and other low aspect ratio spiral microchannel designs. Breakdown of focusing into a primary and secondary fluorescent streak is observed in the lowest aspect ratio channels at high average downstream velocities. Streak movement away from the theoretically predicted near inner wall equilibrium position towards the center of the channel at high average downstream velocities is also detailed as a precursor to breakdown. State diagrams detail the overall performance of each device including values of the required channel lengths and the range of velocities over which quality focusing can be achieved. PMID:22454556

Analysis of PVA/AA based photopolymers at the zero spatial frequency limit using interferometric methods.

PubMed

Gallego, Sergi; Márquez, Andrés; Méndez, David; Ortuño, Manuel; Neipp, Cristian; Fernández, Elena; Pascual, Inmaculada; Beléndez, Augusto

2008-05-10

One of the problems associated with photopolymers as optical recording media is the thickness variation during the recording process. Different values of shrinkages or swelling are reported in the literature for photopolymers. Furthermore, these variations depend on the spatial frequencies of the gratings stored in the materials. Thickness variations can be measured using different methods: studying the deviation from the Bragg's angle for nonslanted gratings, using MicroXAM S/N 8038 interferometer, or by the thermomechanical analysis experiments. In a previous paper, we began the characterization of the properties of a polyvinyl alcohol/acrylamide based photopolymer at the lowest end of recorded spatial frequencies. In this work, we continue analyzing the thickness variations of these materials using a reflection interferometer. With this technique we are able to obtain the variations of the layers refractive index and, therefore, a direct estimation of the polymer refractive index.

Interannual variability in energy exchange and evapotranspiration over two semi-arid grasslands in Arizona

NASA Astrophysics Data System (ADS)

Meyers, T. P.; Krishnan, P.; Scott, R. L.; Kennedy, L.; Heuer, M.

2011-12-01

Continuous eddy correlation measurements of energy and water vapour above two semi-arid grasslands in southern Arizona, USA during 2004 to 2007 were examined to explain the factors controlling the seasonal and interannual variability in energy exchange and evapotranspiration (E). The study sites, a post-fire site (AG) and an unburned site (KG), received 43% to 87% of the annual precipitation (P) during the North American monsoon season (July-September) with the lowest values in the drought years of 2004 and 2005. Irrespective of the differences in temperature, surface albedo, vegetation cover and soil characteristics both sites responded similarly to changes in environmental conditions. The seasonal and interannual variations in the partitioning of net radiation to turbulent fluxes were mainly controlled by P and associated changes in soil water content (θ) and vegetation growth. Drastic changes in albedo, vegetation growth, energy fluxes occurred following the onset of the monsoon season in July. During dry or cold periods of autumn, winter and spring, sensible heat flux was the major component of energy balance whereas latent heat flux dominated during the warm and wet periods of summer. The July-September values of P, E, Priestly-Taylor coefficient and canopy surface conductance reached their lowest and the Bowen ratio reached its highest values in 2004 at AG and in 2005 at KG. During July-September, monthly E was linearly correlated to the monthly mean θ and the broadband normalized vegetation index (NDVI), whereas during May-June the relationship between NDVI and E were not significant. Annual E varied from 264 to 322 mm at AG and from 196 to 284 mm at KG with the lowest value during the severe drought year at the site. July-September E had positive correlation with total P, NDVI and the number of growing season days during that period. Annual P explained more than 80% of the variance in annual E. The study suggested strong coupling between soil water conditions and vegetation on energy exchange and E.

Altered blood glucose concentration is associated with risk of death among patients with community-acquired Gram-negative rod bacteremia.

PubMed

Peralta, Galo; Sánchez, M Blanca; Garrido, J Carlos; Ceballos, Begoña; Mateos, Fátima; De Benito, Inés; Roiz, M Pía

2010-06-22

Altered blood glucose concentration is commonly observed in patients with sepsis, even among those without hypoglycemic treatments or history of diabetes mellitus. These alterations in blood glucose are potentially detrimental, although the precise relationship with outcome in patients with bacteremia has not been yet determined. A retrospective cohort study design for analyzing patients with Gram negative rod bacteremia was employed, with the main outcome measure being in-hospital mortality. Patients were stratified in quintiles accordingly deviation of the blood glucose concentration from a central value with lowest mortality. Cox proportional-hazards regression model was used for determining the relationship of same day of bacteremia blood glucose and death. Of 869 patients identified 63 (7.4%) died. Same day of bacteremia blood glucose concentration had a U-shaped relationship with in-hospital mortality. The lowest mortality (2%) was detected in the range of blood glucose concentration from 150 to 160 mg/dL. Greater deviation of blood glucose concentration from the central value of this range (155 mg/dL, reference value) was directly associated with higher risk of death (p = 0.002, chi for trend). The low-risk group (quintile 1) had a mortality of 3.3%, intermediate-risk group (quintiles 2, 3 and 4) a mortality of 7.1%, and the high-risk group (quintile 5) a mortality of 12.05%. In a multivariable Cox regression model, the hazard ratio for death among patients in the intermediate-risk group as compared with that in the low risk group was 2.88 (95% confidence interval, 1.01 to 8.18; P = 0.048), and for the high risk group it was 4.26 (95% confidence interval, 1.41 to 12.94; P = 0.01). Same day of bacteremia blood glucose concentration is related with outcome of patients with Gram-negative rod bacteremia. Lowest mortality is detected in patients with blood glucose concentration in an interval of 150-160 mg/dL. Deviations from these values are associated with an increased risk of death.

Altered blood glucose concentration is associated with risk of death among patients with community-acquired Gram-negative rod bacteremia

PubMed Central

2010-01-01

Background Altered blood glucose concentration is commonly observed in patients with sepsis, even among those without hypoglycemic treatments or history of diabetes mellitus. These alterations in blood glucose are potentially detrimental, although the precise relationship with outcome in patients with bacteremia has not been yet determined. Methods A retrospective cohort study design for analyzing patients with Gram negative rod bacteremia was employed, with the main outcome measure being in-hospital mortality. Patients were stratified in quintiles accordingly deviation of the blood glucose concentration from a central value with lowest mortality. Cox proportional-hazards regression model was used for determining the relationship of same day of bacteremia blood glucose and death. Results Of 869 patients identified 63 (7.4%) died. Same day of bacteremia blood glucose concentration had a U-shaped relationship with in-hospital mortality. The lowest mortality (2%) was detected in the range of blood glucose concentration from 150 to 160 mg/dL. Greater deviation of blood glucose concentration from the central value of this range (155 mg/dL, reference value) was directly associated with higher risk of death (p = 0.002, chi for trend). The low-risk group (quintile 1) had a mortality of 3.3%, intermediate-risk group (quintiles 2, 3 and 4) a mortality of 7.1%, and the high-risk group (quintile 5) a mortality of 12.05%. In a multivariable Cox regression model, the hazard ratio for death among patients in the intermediate-risk group as compared with that in the low risk group was 2.88 (95% confidence interval, 1.01 to 8.18; P = 0.048), and for the high risk group it was 4.26 (95% confidence interval, 1.41 to 12.94; P = 0.01). Conclusions Same day of bacteremia blood glucose concentration is related with outcome of patients with Gram-negative rod bacteremia. Lowest mortality is detected in patients with blood glucose concentration in an interval of 150-160 mg/dL. Deviations from these values are associated with an increased risk of death. PMID:20569435

Effects and Satisfaction of Medical Device Safety Information Reporting System Using Electronic Medical Record.

PubMed

Jang, Hye Jung; Choi, Young Deuk; Kim, Nam Hyun

2017-04-01

This paper describes an evaluation study on the effectiveness of developing an in-hospital medical device safety information reporting system for managing safety information, including adverse incident data related to medical devices, following the enactment of the Medical Device Act in Korea. Medical device safety information reports were analyzed for 190 cases that took place prior to the application of a medical device safety information reporting system and during a period when the reporting system was used. Also, questionnaires were used to measure the effectiveness of the medical device safety information reporting system. The analysis was based on the questionnaire responses of 15 reporters who submitted reports in both the pre- and post-reporting system periods. Sixty-two reports were submitted in paper form, but after the system was set up, this number more than doubled to 128 reports in electronic form. In terms of itemized reporting, a total of 45 items were reported. Before the system was used, 23 items had been reported, but this increased to 32 items after the system was put to use. All survey variables of satisfaction received a mean of over 3 points, while positive attitude , potential benefits , and positive benefits all exceeded 4 points, each receiving 4.20, 4.20, and 4.13, respectively. Among the variables, time-consuming and decision-making had the lowest mean values, each receiving 3.53. Satisfaction was found to be high for system quality and user satisfaction , but relatively low for time-consuming and decision-making . We were able to verify that effective reporting and monitoring of adverse incidents and the safety of medical devices can be implemented through the establishment of an in-hospital medical device safety information reporting system that can enhance patient safety and medical device risk management.

Color of Cultures of Staphylococcus epidermidis Determined by Spectral Reflectance Colorimetry

PubMed Central

Brown, Richard W.

1966-01-01

Brown, Richard W. (National Animal Disease Laboratory, Ames, Iowa). Color of cultures of Staphylococcus epidermidis determined by spectral reflectance colorimetry. J. Bacteriol. 91:911–918. 1966.—A colorimeter with a reflectance attachment was used to study pigment production by Staphylococcus epidermidis strains grown on a medium containing Trypticase Soy Agar (BBL) and cream. The color of each culture was first characterized by reflectance colorimetry for dominant wavelength, purity, and luminous reflectance (Y) and was then classified visually into 1 of 10 color grades. There was not complete agreement in grading colors by the two methods, inasmuch as cultures that were considered more pigmented in relation to other cultures by the reflectance method were sometimes graded visually as less pigmented, and vice versa. Nevertheless, when the cultures were visually graded as being more pigmented, there was a concomitant increase in the average values of dominant wavelength and purity with a decrease in Y for the cultures in each higher grade. Thus, the nonpigmented cultures had the lowest dominant wavelength and purity values but the highest Y (brightness) values, whereas the most pigmented cultures had the highest dominant wavelength and purity values, but the lowest Y values. These results indicated that the cultures did not produce pigments of different hues (greenish-yellow, yellow, yellowish-orange) each with high, medium, and low degrees of purity and brightness. The value (1 − z), where the chromaticity coordinate z = Z/(X + Y + Z), was found to be proportional to the purity value. An inverse relationship between the tristimulus Z and purity values was also demonstrated. All cultures tested by the reflectance method were also classified according to the type of spectral absorption curve obtained with pigments extracted from the cultures with methanol. A comparison of these methods indicated that determining the type of spectral absorption curve would be better for differentiating strains of S. epidermidis, whereas the use of the reflectance method would be better for determining differences of pigment production within strains. PMID:5932106

Albumin and all-cause mortality risk in insurance applicants.

PubMed

Fulks, Michael; Stout, Robert L; Dolan, Vera F

2010-01-01

Determine the relationship between albumin levels and all-cause mortality in life insurance applicants. By use of the Social Security Death Master File, mortality was determined in 1,704,566 insurance applicants for whom blood samples were submitted to Clinical Reference Laboratory. There were 53,211 deaths observed in this healthy adult population during a median follow-up of 12 years. Results were stratified by 6 age-sex groups: females: ages 20 to 49, 50 to 69 and 70+; and males: ages 20 to 49, 50 to 69 and 70+. The middle 50% of albumin values specific to each group was used as the reference band for that group. The mortality in bands representing other percentiles of albumin values higher and lower than the middle 50% were compared to the mortality in the reference band for each age-sex group. The highest percentile bands represent the lowest albumin values. Relative risk exceeded 150% of each age- and sex-specific reference band for all groups between the 90th and 95th percentile of albumin values. This translates into 150% risk thresholds at approximately 3.8 mg/dL for all females and for males 70+, and 4.1 mg/dL for males ages 20 to 69. Conversely, the highest 25% of albumin values were associated with approximately a 20% reduction in risk in males and a variable 10% reduction in risk in females when compared to the middle 50% of albumin values. Excluding those with total cholesterol < or = 160 mg/dL, or with AST, GGT or alkaline phosphatase elevations, had little impact on relative risk except at the lowest 0.5% of albumin values. When stratified by age and sex, albumin discriminated between all-cause mortality risks in healthy adults at all ages and across a wide range of values independent of other laboratory tests.

Reference ranges of handgrip strength from 125,462 healthy adults in 21 countries: a prospective urban rural epidemiologic (PURE) study.

PubMed

Leong, Darryl P; Teo, Koon K; Rangarajan, Sumathy; Kutty, V Raman; Lanas, Fernando; Hui, Chen; Quanyong, Xiang; Zhenzhen, Qian; Jinhua, Tang; Noorhassim, Ismail; AlHabib, Khalid F; Moss, Sarah J; Rosengren, Annika; Akalin, Ayse Arzu; Rahman, Omar; Chifamba, Jephat; Orlandini, Andrés; Kumar, Rajesh; Yeates, Karen; Gupta, Rajeev; Yusufali, Afzalhussein; Dans, Antonio; Avezum, Álvaro; Lopez-Jaramillo, Patricio; Poirier, Paul; Heidari, Hosein; Zatonska, Katarzyna; Iqbal, Romaina; Khatib, Rasha; Yusuf, Salim

2016-12-01

The measurement of handgrip strength (HGS) has prognostic value with respect to all-cause mortality, cardiovascular mortality and cardiovascular disease, and is an important part of the evaluation of frailty. Published reference ranges for HGS are mostly derived from Caucasian populations in high-income countries. There is a paucity of information on normative HGS values in non-Caucasian populations from low- or middle-income countries. The objective of this study was to develop reference HGS ranges for healthy adults from a broad range of ethnicities and socioeconomically diverse geographic regions. HGS was measured using a Jamar dynamometer in 125,462 healthy adults aged 35-70 years from 21 countries in the Prospective Urban Rural Epidemiology (PURE) study. HGS values differed among individuals from different geographic regions. HGS values were highest among those from Europe/North America, lowest among those from South Asia, South East Asia and Africa, and intermediate among those from China, South America, and the Middle East. Reference ranges stratified by geographic region, age, and sex are presented. These ranges varied from a median (25 th -75 th percentile) 50 kg (43-56 kg) in men <40 years from Europe/North America to 18 kg (14-20 kg) in women >60 years from South East Asia. Reference ranges by ethnicity and body-mass index are also reported. Individual HGS measurements should be interpreted using region/ethnic-specific reference ranges.

Evaluating Thermally Damaged Polyimide Insulated Wiring (MIL-W-81381) with Ultrasound

NASA Technical Reports Server (NTRS)

Madaras, Eric I.; Anastasi, Robert F.

2002-01-01

A series of experiments to investigate the use of ultrasound for measuring wire insulation have been conducted. Initial laboratory tests were performed on MIL-W-81381/7,/12, and /21 aviation wire, a wire that has polyimide (Kapton Registered Trademark) layers for insulation. Samples of this wiring were exposed to 370C temperatures for different periods of time to induce a range of thermal damage. For each exposure, 12 samples of each gauge (12, 16, and 20 gauges) were processed. The velocity of the lowest order axisymmetric ultrasonic guided mode, a mode that is sensitive to the geometry and stiffness of the wire conductor and insulation, was measured. The phase velocity for the 20-gauge MIL-W-81381/7 wire had a baseline value of 3023 +/- 78 m/s. After exposure to the high temperatures, the wire's phase velocity rapidly increased, and reached an asymptotic value of 3598 +/- 20 m/s after 100 hours exposure. Similar behavior was measured for the 16 gauge MIL-W-81381/21 wire and 12 gauge MIL-W-81381/12 wire which had baseline values of 3225 +/- 22 m/s and 3403 +/- 33 m/s respectively, and reached asymptotic values of 3668 +/- 19 m/s, and 3679 +/- 42 m/s respectively. These measured velocity changes represent changes of 19, 14, and 8 percent respectively for the 20, 16, and 12 gauge wires. Finally, some results for a wire with an ethylene tetrafluoroethylene insulation are reported. Qualitatively similar behaviors are noted ultrasonically.

12 CFR 324.152 - Simple risk weight approach (SRWA).

Code of Federal Regulations, 2014 CFR

2014-01-01

... (that is, between zero and -1), then E equals the absolute value of RVC. If RVC is negative and less... the lowest applicable risk weight in this section. (1) Zero percent risk weight equity exposures. An....131(d)(2) is assigned a zero percent risk weight. (2) 20 percent risk weight equity exposures. An...

Electrochemical testing of suspension plasma sprayed solid oxide fuel cell electrolytes

NASA Astrophysics Data System (ADS)

Waldbillig, D.; Kesler, O.

Electrochemical performance of metal-supported plasma sprayed (PS) solid oxide fuel cells (SOFCs) was tested for three nominal electrolyte thicknesses and three electrolyte fabrication conditions to determine the effects of electrolyte thickness and microstructure on open circuit voltage (OCV) and series resistance (R s). The measured OCV values were approximately 90% of the Nernst voltages, and electrolyte area specific resistances below 0.1 Ω cm 2 were obtained at 750 °C for electrolyte thicknesses below 20 μm. Least-squares fitting was used to estimate the contributions to R s of the YSZ bulk material, its microstructure, and the contact resistance between the current collectors and the cells. It was found that the 96% dense electrolyte layers produced from high plasma gas flow rate conditions had the lowest permeation rates, the highest OCV values, and the smallest electrolyte-related voltage losses. Optimal electrolyte thicknesses were determined for each electrolyte microstructure that would result in the lowest combination of OCV loss and voltage loss due to series resistance for operating voltages of 0.8 V and 0.7 V.

Investigation of AWG demultiplexer based SOI for CWDM application

NASA Astrophysics Data System (ADS)

Juhari, Nurjuliana; Susthitha Menon, P.; Shaari, Sahbudin; Annuar Ehsan, Abang

2017-11-01

9-channel Arrayed Waveguide Grating (AWG) demultiplexer for conventional and tapered structure were simulated using beam propagation method (BPM) with channel spacing of 20 nm. The AWG demultiplexer was design using high refractive index (n 3.47) material namely silicon-on-insulator (SOI) with rib waveguide structure. The characteristics of insertion loss, adjacent crosstalk and output spectrum response at central wavelength of 1.55 μm for both designs were compared and analyzed. The conventional AWG produced a minimum insertion loss of 6.64 dB whereas the tapered AWG design reduced the insertion loss by 2.66 dB. The lowest adjacent crosstalk value of -16.96 dB was obtained in the conventional AWG design and this was much smaller compared to the tapered AWG design where the lowest crosstalk value is -17.23 dB. Hence, a tapered AWG design significantly reduces the insertion loss but has a slightly higher adjacent crosstalk compared to the conventional AWG design. On the other hand, the output spectrum responses that are obtained from both designs were close to the Coarse Wavelength Division Multiplexing (CWDM) wavelength grid.

Preload evaluation of different screws in external hexagon joint.

PubMed

Assunção, Wirley Gonçalves; Delben, Juliana Aparecida; Tabata, Lucas Fernando; Barão, Valentim Adelino Ricardo; Gomes, Erica Alves; Garcia, Idelmo Rangel

2012-02-01

This study compared the maintenance of tightening torque in different retention screw types of implant-supported crowns. Twelve metallic crowns in UCLA abutments cast with cobalt-chromium alloy were attached to external hexagon osseointegrated implants with different retention screws: group A: titanium alloy retention screw; group B: gold alloy retention screw with gold coating; group C: titanium alloy retention screw with diamond-like carbon film coating; and group D: titanium alloy retention screw with aluminum titanium nitride coating. Three detorque measurements were obtained after torque insertion in each replica. Data were evaluated by analysis of variance (ANOVA), Tukey's test (P < 0.05), and t test (P < 0.05). Detorque value reduced in all groups (P < 0.05). Group A retained the highest percentage of torque in comparison with the other groups (P < 0.05). Groups B and D retained the lowest percentage of torque without statistically significant difference between them (P > 0.05). All screw types exhibited reduction in the detorque value. The titanium screw maintained the highest percentage of torque whereas the gold-coated screw and the titanium screw with aluminum titanium nitride coating retained the lowest percentage.

Antioxidant capacity, total phenolics and nutritional content in selected ethiopian staple food ingredients.

PubMed

Forsido, Sirawdink Fikreyesus; Rupasinghe, H P Vasantha; Astatkie, Tess

2013-12-01

The total antioxidant capacity, total phenolics content (TPC) and nutritional content of five types of enset (Enset ventricosum) flour in comparison with four staples (teff [Eragrostis tef], wheat, corn and tapioca) were evaluated. Teff, corn and "amicho" (corm of enset) had the highest ferric reducing antioxidant power (FRAP). The FRAP and TPC of teff (1.8 mmol Trolox equivalence/100 g dry matter (DM) and 123.6 mg gallic acid equivalent/100 g DM, respectively) were over 4-fold larger than the lowest obtained from "bulla" (dehydrated juice of pseudostem of enset). Corn had the lowest IC(50) value of 1,1-diphenyl-2-picrylhydrazyl radical scavenging (10.27 mg DM mL(-1)). Teff had the highest crude fat content (3.71%) and some mineral profile (P, Mg, Mn and Cu). Enset products had higher fiber, Ca, K, Mg and Mn content as compared to wheat and corn. Ethiopian staple teff has a potential for developing value-added food products with nutritional and health benefits.

Properties of duck meat sausages supplemented with cereal flours.

PubMed

Yang, H S; Ali, M S; Jeong, J Y; Moon, S H; Hwang, Y H; Park, G B; Joo, S T

2009-07-01

Duck meat sausages were prepared using 10% beef fat (FDS) and 10% hydrated cereal flours including rice (RDS), wheat, corn, millet, and barley to replace fat. Control duck sausages (DS) were also prepared only with duck meat and duck meat plus 10% beef fat. Results showed that protein and fat contents significantly decreased and total expressible fluid reduced with the addition of cereal flours in duck sausage batters. The FDS had higher fat content and lower pH compared with others. Duck sausages with 10% supplemented wheat flour showed the lowest cooking loss among sausages and had similar redness and chroma values to FDS and DS. Texture analysis indicated that hardness of duck sausage significantly decreased when cereal flours and beef fat were added. In particular, RDS showed the lowest values for all texture measurements compared with others. Result of moisture absorption capacity suggested that the decrease in hardness in RDS was due to higher moisture retention for rice flour treatment. Sensory evaluation indicated that DS had significantly lower overall acceptability than RDS, due to its off-flavor, whereas RDS had higher overall acceptability than DS.

Reduced transition probabilities along the yrast line in 166W

NASA Astrophysics Data System (ADS)

Sayǧı, B.; Joss, D. T.; Page, R. D.; Grahn, T.; Simpson, J.; O'Donnell, D.; Alharshan, G.; Auranen, K.; Bäck, T.; Boening, S.; Braunroth, T.; Carroll, R. J.; Cederwall, B.; Cullen, D. M.; Dewald, A.; Doncel, M.; Donosa, L.; Drummond, M. C.; Ertuǧral, F.; Ertürk, S.; Fransen, C.; Greenlees, P. T.; Hackstein, M.; Hauschild, K.; Herzan, A.; Jakobsson, U.; Jones, P. M.; Julin, R.; Juutinen, S.; Konki, J.; Kröll, T.; Labiche, M.; Lopez-Martens, A.; McPeake, C. G.; Moradi, F.; Möller, O.; Mustafa, M.; Nieminen, P.; Pakarinen, J.; Partanen, J.; Peura, P.; Procter, M.; Rahkila, P.; Rother, W.; Ruotsalainen, P.; Sandzelius, M.; Sarén, J.; Scholey, C.; Sorri, J.; Stolze, S.; Taylor, M. J.; Thornthwaite, A.; Uusitalo, J.

2017-08-01

Lifetimes of excited states in the yrast band of the neutron-deficient nuclide 166W have been measured utilizing the DPUNS plunger device at the target position of the JUROGAM II γ -ray spectrometer in conjunction with the RITU gas-filled separator and the GREAT focal-plane spectrometer. Excited states in 166W were populated in the 92Mo(78Kr,4 p ) reaction at a bombarding energy of 380 MeV. The measurements reveal a low value for the ratio of reduced transitions probabilities for the lowest-lying transitions B (E 2 ;4+→2+) /B (E 2 ;2+→0+) =0.33 (5 ) , compared with the expected ratio for an axially deformed rotor (B4 /2 = 1.43).

Density scaling for multiplets

NASA Astrophysics Data System (ADS)

Nagy, Á.

2011-02-01

Generalized Kohn-Sham equations are presented for lowest-lying multiplets. The way of treating non-integer particle numbers is coupled with an earlier method of the author. The fundamental quantity of the theory is the subspace density. The Kohn-Sham equations are similar to the conventional Kohn-Sham equations. The difference is that the subspace density is used instead of the density and the Kohn-Sham potential is different for different subspaces. The exchange-correlation functional is studied using density scaling. It is shown that there exists a value of the scaling factor ζ for which the correlation energy disappears. Generalized OPM and Krieger-Li-Iafrate (KLI) methods incorporating correlation are presented. The ζKLI method, being as simple as the original KLI method, is proposed for multiplets.

Vibration analysis of three guyed tower designs for intermediate size wind turbines

NASA Technical Reports Server (NTRS)

Christie, R. J.

1982-01-01

Three guyed tower designs were analyzed for intermediate size wind turbines. The four lowest natural frequencies of vibration of the three towers concepts were estimated. A parametric study was performed on each tower to determine the effect of varying such tower properties as the inertia and stiffness of the tower and guys, the inertia values of the nacelle and rotor, and the rotational speed of the rotor. Only the two lowest frequencies were in a range where they could be excited by the rotor blade passing frequencies. There two frequencies could be tuned by varying the guy stiffness, the guy attachment point on the tower, the tower and mass stiffness, and the nacelle/rotor/power train masses.

Characterisation of capillary ionic liquid columns for gas chromatography-mass spectrometry analysis of fatty acid methyl esters.

PubMed

Zeng, Annie Xu; Chin, Sung-Tong; Nolvachai, Yada; Kulsing, Chadin; Sidisky, Leonard M; Marriott, Philip J

2013-11-25

Due to their distinct chemical properties, the application of ionic liquid (IL) compounds as gas chromatography (GC) stationary phases offer unique GC separation especially in the analysis of geometric and positional fatty acid methyl ester (FAME) isomers. Elution behaviour of FAME on several commercialised IL capillary columns including phosphonium based SLB-IL59, SLB-IL60, SLB-IL61 and SLB-IL76 and imidazolium based SLB-IL82, SLB-IL100, and SLB-IL111 as well as a general purpose column SLB-5ms, were evaluated in gas chromatography-mass spectrometry (GC-MS) analysis. The phases were further characterised by using a linear solvation energy relationship (LSER) approach according to the equivalent chain length (ECL) index of FAME. Among all tested IL columns, elution temperatures of saturated FAME increased as their McReynolds' polarity value decreased, except for IL60. ECL values increased markedly as the stationary phase polarity increased, particularly for the polyunsaturated FAME. The LSER study indicated a lowest l/e value at 0.864 for IL111, displaying phase selectivity towards unsaturated FAME, with higher peak capacity within a carbon number isomer group. s and e descriptors calculated from LSER were validated by excellent correlation with dipole moments and lowest unoccupied molecular orbital (LUMO) energies, with R(2) values of 0.99 and 0.92 respectively, calculated using GAUSSIAN. Copyright © 2013 Elsevier B.V. All rights reserved.

Thyme and basil essential oils included in edible coatings as a natural preserving method of oilseed kernels.

PubMed

Riveros, Cecilia G; Nepote, Valeria; Grosso, Nelson R

2016-01-15

Sunflower seeds are susceptible to developing rancidity and off-flavours through lipid oxidation. Edible coatings and essential oils have proven antioxidant properties in different food products. The purpose of this study was to evaluate the combined effect of using an edible coating and thyme and basil essential oils to preserve the chemical and sensory quality parameters of roasted sunflower seeds during storage. 50% DPPH inhibitory concentration (IC50) values of 0.278 and 0.0997 µg mL(-1) were observed for thyme and basil, respectively. On storage day 40, peroxide values were 80.68, 70.28, 68.43, 49.31 and 33.87 mEq O2 kg(-1) in roasted sunflower seeds (RS), roasted sunflower seeds coated with carboxymethyl cellulose (CMC) (RS-CMC), roasted sunflower seeds coated with CMC added with basil (RS-CMC-A), thyme (RS-CMC-T) and butylated hydroxytoluene (RS-CMC-BHT), respectively. RS-CMC-T and RS-CMC-BHT presented the lowest peroxide values, conjugated dienes and p-anisidine values during storage. RS-CMC-BHT, RS-CMC-T, and RS-CMC-A showed the lowest oxidized and cardboard flavour intensity ratings. On storage day 40, roasted sunflower flavour intensity ratings were higher in RS-CMC-T and RS-CMC-A. Thyme and basil essential oils added to the CMC coating improved the sensory stability of this product during storage, but only thyme essential oil increased their chemical stability. © 2015 Society of Chemical Industry.

Ab initio study of the positronation of the CaO and SrO molecules including calculation of annihilation rates.

PubMed

Buenker, Robert J; Liebermann, Heinz-Peter

2012-07-15

Ab initio multireference single- and double-excitation configuration interaction calculations have been performed to compute potential curves for ground and excited states of the CaO and SrO molecules and their positronic complexes, e(+)CaO, and e(+)SrO. The adiabatic dissociation limit for the (2)Σ(+) lowest states of the latter systems consists of the positive metal ion ground state (M(+)) and the OPs complex (e(+)O(-)), although the lowest energy limit is thought to be e(+)M + O. Good agreement is found between the calculated and experimental spectroscopic constants for the neutral diatomics wherever available. The positron affinity of the closed-shell X (1)Σ(+) ground states of both systems is found to lie in the 0.16-0.19 eV range, less than half the corresponding values for the lighter members of the alkaline earth monoxide series, BeO and MgO. Annihilation rates (ARs) have been calculated for all four positronated systems for the first time. The variation with bond distance is generally similar to what has been found earlier for the alkali monoxide series of positronic complexes, falling off gradually from the OPs AR value at their respective dissociation limits. The e(+)SrO system shows some exceptional behavior, however, with its AR value reaching a minimum at a relatively large bond distance and then rising to more than twice the OPs value close to its equilibrium distance. Copyright © 2012 Wiley Periodicals, Inc.

Characterization of the major histopathological components of thyroid nodules using sonographic textural features for clinical diagnosis and management.

PubMed

Chen, Shao-Jer; Yu, Sung-Nien; Tzeng, Jeh-En; Chen, Yen-Ting; Chang, Ku-Yaw; Cheng, Kuo-Sheng; Hsiao, Fu-Tsung; Wei, Chang-Kuo

2009-02-01

In this study, the characteristic sonographic textural feature that represents the major histopathologic components of the thyroid nodules was objectively quantified to facilitate clinical diagnosis and management. A total of 157 regions-of-interest thyroid ultrasound image was recruited in the study. The sonographic system used was the GE LOGIQ 700), (General Electric Healthcare, Chalfant St. Giles, UK). The parameters affecting image acquisition were kept in the same condition for all lesions. Commonly used texture analysis methods were applied to characterize thyroid ultrasound images. Image features were classified according to the corresponding pathologic findings. To estimate their relevance and performance to classification, ReliefF was used as a feature selector. Among the various textural features, the sum average value derived from co-occurrence matrix can well reflect echogenicity and can effectively differentiate between follicles and fibrosis base thyroid nodules. Fibrosis shows lowest echogenicity and lowest difference sum average value. Enlarged follicles show highest echogenicity and difference sum average values. Papillary cancer or follicular tumors show the difference sum average values and echogenicity between. The rule of thumb for the echogenicity is that the more follicles are mixed in, the higher the echo of the follicular tumor and papillary cancer will be and vice versa for fibrosis mixed. Areas with intermediate and lower echo should address the possibility of follicular or papillary neoplasm mixed with either follicles or fibrosis. These areas provide more cellular information for ultrasound guided aspiration

Comparison of diagnostic classification systems for delirium with new research criteria that incorporate the three core domains.

PubMed

Trzepacz, Paula T; Meagher, David J; Franco, José G

2016-05-01

Diagnostic classification systems do not incorporate phenomenological research findings about the three core symptom domains of delirium (Attentional/Cognitive, Circadian, Higher Level Thinking). We evaluated classification performances of novel Trzepacz, Meagher, and Franco research diagnostic criteria (TMF) that incorporate those domains and ICD-10, DSM-III-R, DSM-IV, and DSM-5. Primary data analysis of 641 patients with mixed neuropsychiatric profiles. Delirium (n=429) and nondelirium (n=212) reference standard groups were identified using cluster analysis of symptoms assessed using the Delirium Rating Scale-Revised-98. Accuracy, sensitivity, specificity, positive and negative predictive values (PPV, NPV), and likelihood ratios (LR+, LR-) are reported. TMF criteria had high sensitivity and specificity (87.4% and 89.2%), more balanced than DSM-III-R (100% and 31.6%), DSM-IV (97.7% and 74.1%), DSM-5 (97.7% and 72.6%), and ICD-10 (66.2% and 100%). PPV of DSM-III-R, DSM-IV, and DSM-5 were <90.0%, while PPV for ICD-10 and TMF were >90%. ICD-10 had the lowest NPV (59.4%). TMF had the highest LR+ (8.06) and DSM-III-R the lowest LR- (0.0). Overall, values for DSM-IV and DSM-5 were similar, whereas for ICD-10 and DSM-III-R were inverse of each other. In the pre-existing cognitive impairment/dementia subsample (n=128), TMF retained its highest LR+ though specificity (58.3%) became less well balanced with sensitivity (87.9%), which still exceeded that of DSM. TMF research diagnostic criteria performed well, with more balanced sensitivity and specificity and the highest likelihood ratio for delirium identification. Reflecting the three core domains of delirium, TMF criteria may have advantages in biological research where delineation of this syndrome is important. Copyright © 2016. Published by Elsevier Inc.

Pier and contraction scour prediction in cohesive soils at selected bridges in Illinois

USGS Publications Warehouse

Straub, Timothy D.; Over, Thomas M.

2010-01-01

This report presents the results of testing the Scour Rate In Cohesive Soils-Erosion Function Apparatus (SRICOS-EFA) method for estimating scour depth of cohesive soils at 15 bridges in Illinois. The SRICOS-EFA method for complex pier and contraction scour in cohesive soils has two primary components. The first component includes the calculation of the maximum contraction and pier scour (Zmax). The second component is an integrated approach that considers a time factor, soil properties, and continued interaction between the contraction and pier scour (SRICOS runs). The SRICOS-EFA results were compared to scour prediction results for non-cohesive soils based on Hydraulic Engineering Circular No. 18 (HEC-18). On average, the HEC-18 method predicted higher scour depths than the SRICOS-EFA method. A reduction factor was determined for each HEC-18 result to make it match the maximum of three types of SRICOS run results. The unconfined compressive strength (Qu) for the soil was then matched with the reduction factor and the results were ranked in order of increasing Qu. Reduction factors were then grouped by Qu and applied to each bridge site and soil. These results, and comparison with the SRICOS Zmax calculation, show that less than half of the reduction-factor method values were the lowest estimate of scour; whereas, the Zmax method values were the lowest estimate for over half. A tiered approach to predicting pier and contraction scour was developed. There are four levels to this approach numbered in order of complexity, with the fourth level being a full SRICOS-EFA analysis. Levels 1 and 2 involve the reduction factors and Zmax calculation, and can be completed without EFA data. Level 3 requires some surrogate EFA data. Levels 3 and 4 require streamflow for input into SRICOS. Estimation techniques for both EFA surrogate data and streamflow data were developed.

Annual nitrate drawdown observed by SOCCOM profiling floats and the relationship to annual net community production

NASA Astrophysics Data System (ADS)

Johnson, Kenneth S.; Plant, Joshua N.; Dunne, John P.; Talley, Lynne D.; Sarmiento, Jorge L.

2017-08-01

Annual nitrate cycles have been measured throughout the pelagic waters of the Southern Ocean, including regions with seasonal ice cover and southern hemisphere subtropical zones. Vertically resolved nitrate measurements were made using in situ ultraviolet spectrophotometer (ISUS) and submersible ultraviolet nitrate analyzer (SUNA) optical nitrate sensors deployed on profiling floats. Thirty-one floats returned 40 complete annual cycles. The mean nitrate profile from the month with the highest winter nitrate minus the mean profile from the month with the lowest nitrate yields the annual nitrate drawdown. This quantity was integrated to 200 m depth and converted to carbon using the Redfield ratio to estimate annual net community production (ANCP) throughout the Southern Ocean south of 30°S. A well-defined, zonal mean distribution is found with highest values (3-4 mol C m-2 yr-1) from 40 to 50°S. Lowest values are found in the subtropics and in the seasonal ice zone. The area weighted mean was 2.9 mol C m-2 yr-1 for all regions south of 40°S. Cumulative ANCP south of 50°S is 1.3 Pg C yr-1. This represents about 13% of global ANCP in about 14% of the global ocean area.